LOCUS       DAYAKB010000001       121322 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.001, whole genome shotgun sequence.
ACCESSION   DAYAKB010000001 DAYAKB010000000
VERSION     DAYAKB010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 121322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 121322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..121322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.001"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(194..2263)
                     /locus_tag="ACGI3L_000001"
     CDS             complement(194..2263)
                     /locus_tag="ACGI3L_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFG9195742.1"
                     /translation="MKNYEIKNHTIEVDFSNYRINKRLLDYFIYNENDVKTAYIEAIL
                     KNKDEIIDLSEYDRVLVSITKSDGQKVNGECEVVDAENGIVEIELSRQALASVGINTF
                     QLSLVKDGTLLNTTNLYYRVEEGMINDDDITSTDEYGVLLVIIAQAEEIIKNNKELTK
                     RVEQLEITILGNEEVRDKAEQIRIYNEDIRNIQEEEREFNELTRQNQEANREESIQNM
                     QIQVDDKLTDCQLQLDEMIDAKSKEIDNIVDDKMLDVQVQTDKKFQDLDTRANNTFDL
                     YDKTFEDKLTDNQEQIDYKLDEVNQAISNVEDCIDESTTKLDTKIKEVDDKIVEVNTA
                     KTDMTTTVSNKITEFENRFEELESLDARGELIQARESVDGTVKDTLKDRLTYDFEKVN
                     EKIAEMTSAATNVAFSKSYVESDWIADGEYFKLTVNHNLVTENIFVAILDEVTKKSMT
                     NSYTIVDSNTIEIFNELAINVRVTVVNGNTNKEVIPNTINDNITTLDSTYSSVKIDAK
                     FDESLTKINENKSNIATNLEKINLIQSKVGSSELSTVSKNISDAVNELDASVKILQEG
                     GNLGQQLDSLKAKYDALSDKVLDILIYLELESGAVDEVGQWYDNLTDSKGILSIEGLR
                     LDTDRRRIFGSEGNVIFNKIDIPFSCYKVKYIHELDDNFIETISNTSTNAGANSIELE
                     KFSYEVK"
     gene            complement(2275..2430)
                     /locus_tag="ACGI3L_000002"
     CDS             complement(2275..2430)
                     /locus_tag="ACGI3L_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195743.1"
                     /translation="MEVNLQKAYTVAFEEIKSLYNELILYKALNMQQQEEIENLKKEL
                     EEQNKEQ"
     gene            complement(2432..4354)
                     /locus_tag="ACGI3L_000003"
     CDS             complement(2432..4354)
                     /locus_tag="ACGI3L_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098024 - virus tail, fiber [Evidence
                     IEA];
                     GO_process: GO:0019062 - virion attachment to host cell
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HFG9195744.1"
                     /translation="MILDNSPADSWIRITGVIVTYNNTLYQVVDTETNKKYIYWDADN
                     PGTLKVSNVRLPEGNTQFLVVVNDNGKHTEVPINSSIFDISFDGNSRKNTEEQIWGLY
                     ETDEKHNEKFVVIEKDIDGIHQTVLEVQEDASHIKENMSLIDQRAENVNILVKEVTKN
                     FGGSQENITLRENINKAIIKLNADLGTFSSNMSNYFNDNEVTDEEKEKIDIELNLLDT
                     DKASLYTELQKLIDRTTGVDLVAINTSKTALDAASTNLNSIINSVISDSIITPSDRIL
                     AINANAQYNLKINELKNTVDKIYITGMGGSISEEFSQINATAKEIKLEVAKVDGATKT
                     NAAEIKLTKDDITMMVTRNNSGSIVGIKPDKIEFGFNDISNYVEISRSGLTVNQGAIA
                     CDILTTPSGHEPIIRLFGSSRSGFAIDARQSDGSSQASAIRLKYDSNNYFWVGYDTAE
                     IYVDGEEHFIVERDDTFVRCGGATFTFTNGDSLGVGYSFYPERSVTDLGCERYKWRYL
                     YARSTLSESDKKFKENIVYIKDIKNRTRSSITPTPFLDFIRDDFKPATFDYIAEKDRT
                     IADSQIGFIANDFKDSYVGKTFLYDYGEENGLMFSPSGYTTVVATALQEEIQKREELE
                     MIINELNEKINNLGGY"
     gene            complement(4356..6071)
                     /locus_tag="ACGI3L_000004"
     CDS             complement(4356..6071)
                     /locus_tag="ACGI3L_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195745.1"
                     /translation="MHFNVNLKQIKSDYTLTIHKMNKSFLGQIPINFLNSIKRELGGV
                     DEIQLTIPKYITDRFLFNKIINPIFEEVKEERLICLNNKEYFVVKNVVTTDDKLKVVT
                     AKSKEVKLGKIDVNIEDYGLQMFTKDEEASIISLNDYLKQETGWKLGYVDDSIAYETD
                     SEGNKREKVRWQESINSNWLDYFNNELKEQFECIADFDTYNNLVNLYHIDSFGDNIQL
                     YLSHDNYIKSLERTTNSDDIVTRLKLEGSEDMDIIGATVTGYDYIENYSYFLDNKEMS
                     EELSRAIKKYQEMNEIREPIWRELIDTKLKKQRERDSKSNEWLHVIETIKAKKDIKKT
                     YDNPEHKDEVNSAKLAVEISELEDKKVILDVQIKHLEEEIAKLDESIKDINILCKRET
                     STDEDGYLIFNEALLDELNEFLYYDTYTNDAFLKVEDLIAEGKRQLSLKCIPTKEWTL
                     DVINFLDRIIDINFRQHWKGDLSLGDIIVLHSKESKEEELVYFTSFTQNFKNGKLDTL
                     ELTLSNKKVKEDDKRTIADYLTKAEHATRTLNSKRHLFIQQQKKRINLPDEYIPKKNI
                     QKELM"
     gene            complement(6129..6464)
                     /locus_tag="ACGI3L_000005"
     CDS             complement(6129..6464)
                     /locus_tag="ACGI3L_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFG9195746.1"
                     /translation="MKWNIFYTKDSHKDLKKLDNSQKKQVLKAIEKVSYNPLPSPDGY
                     GKPLGNKGNNNLTNCFKIKLRGIGIRVVYNLVMENNIMRIIVISVREDSLVYDIASER
                     VKEMATTTE"
     gene            complement(6464..6799)
                     /locus_tag="ACGI3L_000006"
     CDS             complement(6464..6799)
                     /locus_tag="ACGI3L_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFG9195747.1"
                     /translation="MLNNRDLLMANMLNTIVPISRFNKGEANKIFDEVKKSGSKIVVK
                     NNIPTCVLITPEKYEEMINAIEDYKLLLETEKRMKNINEEELISQSELMKDLDISEKD
                     LENIEVDFE"
     gene            7140..7301
                     /locus_tag="ACGI3L_000007"
     CDS             7140..7301
                     /locus_tag="ACGI3L_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195748.1"
                     /translation="MEYLVLFLIMIIMITRIIIHLTKLIDAILNLKASIRKLKNHQTG
                     GSSDSESNT"
     gene            complement(7540..13647)
                     /locus_tag="ACGI3L_000008"
                     /pseudo
     CDS             complement(7540..13647)
                     /locus_tag="ACGI3L_000008"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            complement(13931..15409)
                     /locus_tag="ACGI3L_000009"
     CDS             complement(13931..15409)
                     /locus_tag="ACGI3L_000009"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195749.1"
                     /translation="MVEEFKIKTSIELDDKEAREKLEKLKNSGQDKPIKLNLKIGELD
                     KLSQQAEQLKGIFNKAFKIDSTALSNLKQIESTMKEINKLSRRSQDSLLGGGSGNTGN
                     INNEQQDLIRQYKEISNVVSRLQNQMRTGLGDSSIERTTEQIERLKRQLDSVYAQMNS
                     SSQARMDMFDASRATRDLADMNRSLSRIEDMATQASARLNGLGDNIDTDKVNRLRNEL
                     QELKQIASRNIDLNLDVGNIVNRIQEINQEVRNLERVDSLRSNFSRIEDSIRQAFGNE
                     RVEAFRRSLEQLQGSAGNLNGDFNNIFDRLTREMRDARQEAERLNNTVSKGGGFFNDF
                     YSSIASYSIGDMLGDALTDGIRSMKDVILELDSSMTDLKKVAEPTDIDSTSELDKIRE
                     KAIQTAKDVGMSASQVQESIASSLQAGIGGMQESIAAARQSMILANVGDMDVEGASSA
                     VNTIINGFRIEPLKEMQVQVGNTTKKTTELTAAMDMLNCLAC"
     gene            complement(15471..16454)
                     /locus_tag="ACGI3L_000010"
     CDS             complement(15471..16454)
                     /locus_tag="ACGI3L_000010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195750.1"
                     /translation="MFKKILLIGIVSILGFGVVGCSDSNKNEVVKKEKKEVSLEGLTH
                     IMKNYDKMTDYSIDKFSNEEENDFNKENCIIDDNDEKTKEALEITDKTSKDMNELIAL
                     SKEYKKNDLNDTKKKFEDRMDEFKSDINSYMVDITPFETPESLLKELEEKENEKIIWK
                     ERKFFIIDKKLDSKFMDSENRPINSWFKSNYDLRKFQIDFQNTVLTGNEQLKKNFDNI
                     KMNIDDNNSHELLKNQTKLKKIIKYWGSELYAMNSYIRSNEITLSGNMNILLSKFEEE
                     IRCYRTIESSFSHDLKSTKQNLDNDSTMMPSYIESAEKYYNDIKEMETYWN"
     gene            complement(16684..17394)
                     /locus_tag="ACGI3L_000011"
     CDS             complement(16684..17394)
                     /locus_tag="ACGI3L_000011"
                     /inference="COORDINATES: protein motif:HMM:NF021378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9195751.1"
                     /translation="MEEYSGRLIFIGVVVGSFIVYCFIKNAIDNAREKEARLERIAER
                     NREKTKVEKAIQKNISMAKCQAFGNSNSDSVILSNNGKISIIHAGFKTAVKKNIEDLV
                     SIKFNMQVSEKNQMRIISIVPTYDKYTFVEKIYLTLIFELNTYEVFYIPEHKNINNAD
                     IQEKIKEMERFKLVVENEAAKFKNAKIESNNDIKKDDDDISKISNSLKELHSLKDQEI
                     LTEEEFNEKKKVLLEKIK"
     gene            complement(17494..18534)
                     /locus_tag="ACGI3L_000012"
     CDS             complement(17494..18534)
                     /locus_tag="ACGI3L_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HFG9195752.1"
                     /translation="MDIINKENVKRIISFNNELFGEIRTVEIDGKMYFVATDIAKALG
                     YAKPNNAIERHCRYTLKQGVPHPQSKTKTLEVNIIPEGDVYRLITNSELASAEKFERW
                     VFDEVLPSIREHGAYMTNEALEKAINDPDWTIKLLTELKKERATKEKLRVEQEKNKPK
                     LELANAIESSSSSILIAQLSKILNQNGVDIGQNRLFEWMRNNEYLIRKKRADHNTPTQ
                     KSMDLKVLEVSESTGVDKDGNTIVRYTPIVTGKGQIYFLNKILKENSQVLKRFMINND
                     YIKGVMVEIGKTYAIYDHEYYGFIGILKSVRNEKIRVEEIGDISRSRDIPICMIDYIE
                     EASKEDINKYLK"
     gene            18793..19242
                     /locus_tag="ACGI3L_000013"
     CDS             18793..19242
                     /locus_tag="ACGI3L_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195753.1"
                     /translation="MIGEKLKQLRIKNNLKQSDLARILDVTQGAVGMYENDKRTPSPE
                     LIVKLAEYFNVTTDYLLGHTKTNYSVSANIPGMPSIVCEDNSIYDILDGKKDIKSLKD
                     MNKFLENTDYNNEVKEVLKKYMQLDEMDRKAIERMIDNAYERLKEDN"
     gene            complement(19577..19735)
                     /locus_tag="ACGI3L_000014"
     CDS             complement(19577..19735)
                     /locus_tag="ACGI3L_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195754.1"
                     /translation="MGRCKFKPIQATPELSGKDAELFIEQVFTKPSQKEMERNERLLN
                     IITSCRTL"
     gene            complement(19905..20177)
                     /locus_tag="ACGI3L_000015"
     CDS             complement(19905..20177)
                     /locus_tag="ACGI3L_000015"
                     /inference="COORDINATES: protein motif:HMM:NF025574.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS-like domain-containing protein"
                     /protein_id="HFG9195755.1"
                     /translation="MIIKFLEFGKSLGTRQLGKKIRTDIINSIKKGEKVIFDFNGVSI
                     ISNSFADECFGKILEEMELQTLVNNTEFKDTNDNIRIIIKSVLRKY"
     gene            complement(20192..21109)
                     /locus_tag="ACGI3L_000016"
     CDS             complement(20192..21109)
                     /locus_tag="ACGI3L_000016"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195756.1"
                     /translation="MNSQNIECINLSKIGNIRGLLNVLDKYKELSSNDTLYLNIDCNG
                     MIFPEYLCILVSWIKFLEYKGIKVVKKILNENDYVSRINFYNEIGYDYIENFNRHNGN
                     GKFIEITRIDNTNTNYIVNNIMNVIKCNIELHDTVFDCLNYCLFEVVDNINEHSESPI
                     GGYIVVQNYPQKNILKIAIVDSGLGIYNTLKNSGKEEYKNINESDALKCSIKEKNSRF
                     QKRGYGLYHTSNFMKHNKGIMSMHSGNSTLSINNGKIKTYSSGFWQGLIVYFNINTNK
                     SVDINDIFDGKENIPISVNESDDILNGYL"
     gene            complement(22235..22675)
                     /locus_tag="ACGI3L_000017"
     CDS             complement(22235..22675)
                     /locus_tag="ACGI3L_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195757.1"
                     /translation="MEFKSLDELVAYTKNKIAASMPEVGKEMKEIMKEEVNKQVYSGY
                     TPVGEWNPNVWGGRTGQLLDAIDVTELSSNSVTSEIQNNGNWVDAFTRNSAFPMERLE
                     KGKVWGVGGYRPQTNIMEESNSKAQERVPKCFKSKMNELGVPVK"
     gene            complement(22676..23125)
                     /locus_tag="ACGI3L_000018"
     CDS             complement(22676..23125)
                     /locus_tag="ACGI3L_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195758.1"
                     /translation="MNKIQVDKLIQDEVRAIIPIVDESGKEEYIEVRNPDKETKEEIL
                     NKIWVGMESPDLALSQEDILEMLIDKLTNIELNIEIEDLINGNISSELENVMYYIGQI
                     ENELTASLLMNTEIKLGQMKNEILQDRVLKETEEIEKMNNIKDKVVN"
     gene            complement(23139..23924)
                     /locus_tag="ACGI3L_000019"
     CDS             complement(23139..23924)
                     /locus_tag="ACGI3L_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail domain-containing protein"
                     /protein_id="HFG9195759.1"
                     /translation="MVFLDDKFLFDNISSESMNIKLVTLGDDEILNEYGLPYEEAIKS
                     DSTFNKNPCYSEDETTIEPITLQFCLCSEHGEAYEWDDYTLENICNWFWQREFKPFIS
                     YDNIEEIYYLKARKIIKRYTKDKKGVLEIEFQPYTNYAYRSFQKVITVKDTREIKLNN
                     VSNVDEEYAPVIDIECLKEGDITIRNSTISDNEEDNLVISGLELNEKITIDNLYYTVL
                     NSSGENRFNIVNRKWIRLRRGVNILKFTGNCKVSIKCKYPIIK"
     gene            complement(24021..24839)
                     /locus_tag="ACGI3L_000020"
     CDS             complement(24021..24839)
                     /locus_tag="ACGI3L_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195760.1"
                     /translation="MKRFAVKDAGNVIVKNKVTGEVLFYSQDLNAFNFKMDSESVYAK
                     AKGANTIAFDGAITASLTMEQEVIQMAQLAMLLSSDIDEKTAKVGKRKVLTSDSTKKV
                     TLENIKPVANSISVYSIESDGISIIKKLQFTSSVTGANTEITISTADFNAGDKVAVFY
                     LEEIPKAKVVKIKEESTAPNYVVEAEVMVKTVDGEYMVLYMSVPNAKAQRSIELNLTA
                     ENPSGFNMTLDVLPDENKEYATFTFIGDENLNPARMASMLGVELEDEKDTKPKK"
     gene            complement(24884..25687)
                     /locus_tag="ACGI3L_000021"
     CDS             complement(24884..25687)
                     /locus_tag="ACGI3L_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195761.1"
                     /translation="MLENYYITGLPIKLSETLGTVYQPTIEELIKFDMANLEIVNPFL
                     VLEKSYSQLCNEESFELKCKYDAIPILDLMMLTSRRDSSEEIELLSDKIKKSLSILYK
                     TDIKNIEYMNKIKIGILIKFDDKKKNAFISREDFGLISDLILEMFCIDKKNLFKDDED
                     KWIENTGSEREKQLIAHFKEKERKKREKEAYHLCDYINVVQNIDGYVPIDVILKMTYW
                     QLINVYKTKIQFKNYNESLGYAWSFKYQTDMDKMKHWSKEIKIPLSTVK"
     gene            complement(25687..26181)
                     /locus_tag="ACGI3L_000022"
     CDS             complement(25687..26181)
                     /locus_tag="ACGI3L_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195762.1"
                     /translation="MAFPNKMISNIGTTLMSNQDFAKFMIYNNESQKDILSMPDIKNP
                     VKELRNKKVFFNRRVEKVLKEADVSVYITLFKYNLYKDRSRIIKTTNIEIGVVCHDEC
                     QDTFNGLRDAALVCCIVDTITENEEIAGIGKIKLESCSPMFNLDTSYNGFSIVVSSES
                     FGDM"
     gene            complement(26196..27185)
                     /locus_tag="ACGI3L_000023"
     CDS             complement(26196..27185)
                     /locus_tag="ACGI3L_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195763.1"
                     /translation="MSYLSDIKKRIGLGCSTPKEKRILQLRLSFKKYLKETPTCIEVQ
                     ITDIDEICITEDTKRAVVAINDITNNDKRALDEKNLLVESDLDVDVGCYLFYDNCYWL
                     TIFKEHKEMDTYKHFIIKRCNQFFNYKYKGQMYKIPIAVENLTLYSDGMADNKYTSIS
                     DTKRQLYFGSNPVTKTIDIDTRIMLTGKTVFRVTSINDFEYNGRETGADGLIKAICLQ
                     DALISKDDTINNIAWNDLSENDSVIIPFSKIMGYEVINLGEENEYIIDHFQGVKWLLD
                     KQYRYCNIINQDEKKCVIQANTLAKYSGSEALLLAKDKDTNEIIDTKKITLRG"
     gene            complement(27187..27816)
                     /locus_tag="ACGI3L_000024"
     CDS             complement(27187..27816)
                     /locus_tag="ACGI3L_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195764.1"
                     /translation="MGTPLVKIYKKFLDAINDEEMLLLSNEIIEKMMYSYLEDAIVDF
                     NQCKKDLTIKYVDEKGEEIIPAAQLSYTSNYSNKNAEITLMGKDTKEEYELDKDYTIS
                     FEDEKFIISFVVETTEEIIFKYKYLGEIVSDLDLEEIKILSYGMQIHWLQPKINREEN
                     LKQMLTDSDYNAKSGANMLAKLQAREEQLRTRFNKYQQRYMLKNFEGWN"
     gene            complement(27831..28463)
                     /locus_tag="ACGI3L_000025"
     CDS             complement(27831..28463)
                     /locus_tag="ACGI3L_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195765.1"
                     /translation="MARAKKENISKTEVKANTLEKDIKSTLNKKEARLNRLELQRKLK
                     QKKQEIDIEIKNISTWDVDYIDPREKQQIFSLSKVGSKDSTEFIDLDTLYRIVRRSPG
                     FFEEHRLIISDVDSLDVECTPMDIIDFLGLNSLYEHIRNPNEDYLEYFLSDKVDINSF
                     EKILNKNNVELTRRLAERAIDLHKKKKFDSGLKAKLLAKRIGIEDLYLFS"
     gene            complement(28516..29526)
                     /locus_tag="ACGI3L_000026"
     CDS             complement(28516..29526)
                     /locus_tag="ACGI3L_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195766.1"
                     /translation="MATAKTLKRIAHELYTDTFREYTDRDGNTITYRDAESAIKNKLK
                     EMMGGEKYNYYKFQENKWGFYNLISELISDDINRLNEEVFSPFCDFENFDLGDKKEFT
                     VENTNLFKVANIADGVNSTRRQRLLNKKVPTTAFKLSVAIYEEAERFITGRINWVVFV
                     NRVSDSYHYDIARRIAKTFEGAYSTINAKFQATGNSDKVLLELIAKVEGATGKKPIIY
                     GTPLALSNLEGVQTDLEKEEKRKYGFIQTFRGGYKVLSLPNAYDENAAEGKEWALDNK
                     AIYVIPDGEKIIKLGTEGDVLVIENTDEKERDDQQIEYFMAQKIHLGVVTAAKFGVYK
                     IQ"
     gene            complement(29614..30111)
                     /locus_tag="ACGI3L_000027"
     CDS             complement(29614..30111)
                     /locus_tag="ACGI3L_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195767.1"
                     /translation="MKKDKAIIQTDKVKNPDVLTGKYVVPSEDTNPINLENGAVINIG
                     ELEDTEYGRDTHKIYKVTNDTLDWGIVDDPATMYDERLDERDYEVSPGQICRCRRLKK
                     GDEVTISLLHIADKSIAVKDKLQLKSDSFQFEKLPTADAKTPVAEVLELWNYEGQDSV
                     TIKVL"
     gene            complement(30126..31559)
                     /locus_tag="ACGI3L_000028"
     CDS             complement(30126..31559)
                     /locus_tag="ACGI3L_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195768.1"
                     /translation="MKKIKILKLPCNLKHYSDKKKLEELNSNLLPVYIYVMHEGTNPN
                     GTKFYEEAIDKAEPTLKNVPILGYVKINEDGKYDFDGHNVLTQVVQTDEGFILEEYYE
                     ERIIGVIPETNKYEKVEIDGQKYVKCKGYIYKSYSNHAYDIIMDSDEIEISMEIDIND
                     YQLDDSDGFYNIKDYVYHGITCLGSDVKGAMGSNCCLTKFSRKINYKEEISKICSEIY
                     ALEHGEGEKNLPNKNQKLNKNSEGYALAVSNLSTEIRNKLKEYKVETENWYGEKVEVQ
                     AFYYNDLIPEENIAIVEDEINWGYYYGIPYIVNEDAVILDYENKKSYIQTWREKQEGE
                     IVQVFSRQEKLKKEIIEKFTEKQKEISNLKASLEPLQAFKEEKEFELFKSKVDDVAQK
                     FELAEDEIKDIKIKAYNKEITLDEYKKELGYIFALKTLSNKQSEKENFSINDDKNNTI
                     KIPISNNNDSFSEPEEISFIKKYSDKE"
     gene            complement(31566..31757)
                     /locus_tag="ACGI3L_000029"
     CDS             complement(31566..31757)
                     /locus_tag="ACGI3L_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195769.1"
                     /translation="MSKFIYAFSEDDKKLLMEKGYRFICENKLNNKTLYVFENKSKLI
                     NNFSNEEMKRFIFTSKIRF"
     gene            complement(31760..33238)
                     /locus_tag="ACGI3L_000030"
     CDS             complement(31760..33238)
                     /locus_tag="ACGI3L_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195770.1"
                     /translation="MGKKNNNKSKSKDNNSTQNQINMLNAQIGKYASVKESTTLATEM
                     YKLRSISRDKLRKALSNPYQISNTDILQDASMILKATSGTYRRVLNLISNMNTFDHIL
                     YPKDISRLKTKEKITKAYMNSASQLEKYNIKFTSAWITEKVLELGEVYLYKIEDNSGM
                     VLQQIPAKFCMITMIENNVMRYAINIKKLTDKNIISFPEEIKNIYKKYKSNLLTREEL
                     IDNTYFQLSDKAVAFNYDLDSVKGVPFFCFIFDDLMELEDMKDLKSTNAVIESIKLIH
                     QKIPFGKNDEPLVDLNLIPIYHNSTKANLPKGTAITTNPLELETHTLSDGKSKINDYV
                     KEAKEFIFDNAGINTALLNSDKINNESILNGIIADSLIPMRIQQMIENWVNFELNKDK
                     KANLFNMKFIGTTHFNKMNLSKQYREDMGYGGSKSLFIASTGFTPLQAINTLQAEKLM
                     GFDEFLIPQQTSHTQSSGRPDKSDIGTDNGNSTQAKGNGEND"
     gene            complement(33255..35003)
                     /locus_tag="ACGI3L_000031"
     CDS             complement(33255..35003)
                     /locus_tag="ACGI3L_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195771.1"
                     /translation="MRTKYEKRELSSNDSSRNLLESIGEYWGAFYLANPHRFCMDYFG
                     FNLHLFQQILIYMMMKSDQFVFIASRGLGKSWLLGVFCCVIAVLKPGTCVLIAAKRKK
                     QAKLLITSKILGDLYLKSDTLKREIKSFQVNAQEVSIDFWNGSRIEAVVSNDDARGYR
                     ANVLIVDEYRMVDEGTVNDVLVPFLTNPRQPGYLQNPKYRYMQEENKEIYLSSGWYSQ
                     HWSYKKFMETVKGMLSGEDMFACSIPFTCSLEHGLLTKKRILKEMKKESMSDASFMME
                     YCGVFYNESDDAFFKSSWVNPCRVLESMFYPPSDIEYLENKKKRDKKYHLNKIKGEIR
                     IIGADIALARGVKNDNSIYTLMRMLPNEGTYKRCVVHIEAYNGMEAEKQAIRLKQLFS
                     DFQADYMILDTQGIGTTVWSYIQKANYDSDRDEWYDAYTCFNEDNTVDKSLAKKSLPV
                     VYSMKAYADENHKMAMSLRDVLTNRTLELPISDIEAKEMILEKEMIKADEIDKKAELE
                     AKYIAPYLQTTALVNELINLEYSADGGKIKIKEKSGARKDRYSSLAYTNFLADYLEEK
                     EKRKNRNNQKTVMIYW"
     gene            complement(34993..35892)
                     /locus_tag="ACGI3L_000032"
     CDS             complement(34993..35892)
                     /locus_tag="ACGI3L_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195772.1"
                     /translation="MAISKTKCLNCGEEKYTDRYFWKSHSEIFTLNKRLPVCKECFRA
                     RFLLLNGCYNGELVKALKHICFNFDVYFDEKLAKELADKKNKDELIDEYMKIINRNSK
                     YKGKTSLDNLLKEIYTGNNNDKNIVINDEIKLKWGRGFDDYEYKILERKYKEYKEYYE
                     PESLTERKLFEEICIIELEKDKSREKGDMKAFNDLSKLVSSKMQDAEIKPSQKKKAGD
                     SQDDTFGMKMMIYEKNKPVKDRLKEYEDVDGFEAYVNKHMKKPLAVALGLATGKYSIN
                     DGDKDIKFKDDVRDILEGNKNED"
     gene            complement(36023..36607)
                     /locus_tag="ACGI3L_000033"
     CDS             complement(36023..36607)
                     /locus_tag="ACGI3L_000033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195773.1"
                     /translation="MSNNSIRLENRENIVEQIIEVSEILSEFIYELSKEIDKIIVYSV
                     GGNHDRVLPKKDENLDKDNFTLLIDEYIKLRIKSLGNVIFQENIYDNDIIVAKICGNT
                     CFAVHGDKDKMSTAIPKLTSLIKLIPDYIFMAHLHNCKEDNYGESEICVNGSFSGTDS
                     YAKNLRLSSHAMQKLMIFNESGRICTYNINLSKL"
     gene            complement(36728..37891)
                     /locus_tag="ACGI3L_000034"
     CDS             complement(36728..37891)
                     /locus_tag="ACGI3L_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFG9195774.1"
                     /translation="MIKTHRVKLKLTKSQFELVREKQMESANCWNYIINLSKNYYFQH
                     KQWISNYDIQKLIKGKFNLSGQTIQAISTKFCANRKTISELRKKGNSKAKYPYKIKKF
                     YIIPLKNQDIRTNKQGNLKLTLSAGRYLELDFNVENIKTAEIVWRNGYYLYYTFDDGI
                     INPTPKGNNTVGVDLGEIHSIASITNEGIGFIISNREGRSIKQFRNKMYAYISKRLSR
                     CKKGSRQYKRLWKLKNTIRTKTDNQLINLYHQTTRKFIDFCVEQQVCEIVLGDIKGIE
                     KNTKKKKRLNRINRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPQGRTYSCTCGYKTHRDIVGAWNILNKKHKYNLVDFKINHNQPINLKVSTI"
     gene            complement(37972..38310)
                     /locus_tag="ACGI3L_000035"
     CDS             complement(37972..38310)
                     /locus_tag="ACGI3L_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195775.1"
                     /translation="MSIIKAVGRFQGNILERNEQRIEMIRFVKQDSNLLVIIKKFLDN
                     VKDYNLKNVRYIIENELFFERVSIDVICRYMDLLNRCVNIEDDFEEIYKLKAEVGFRR
                     TMDCLFRQVH"
     gene            38523..38945
                     /locus_tag="ACGI3L_000036"
     CDS             38523..38945
                     /locus_tag="ACGI3L_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195776.1"
                     /translation="MFGERLKELRIKFGLKQYELAEILNVSQSTIGMYENDQRTPPAE
                     SIVKLAEYFNVTTDYLLGHTKTNYSVDTDKTKIQSIIDSLASYESIKFPKEKFSSLDE
                     YIDFINSDEDIKETIKMYIRLDKEDKKAIRRIIENSLK"
     gene            complement(39046..39234)
                     /locus_tag="ACGI3L_000037"
     CDS             complement(39046..39234)
                     /locus_tag="ACGI3L_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195777.1"
                     /translation="MKNNKGTILEKCEVIKQEDGTYKFIEHTKNGDNEVLSSDVFDQY
                     IGKTDLNITIRLSETIVQ"
     gene            complement(39607..40224)
                     /locus_tag="ACGI3L_000038"
     CDS             complement(39607..40224)
                     /locus_tag="ACGI3L_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195778.1"
                     /translation="MVKYNVHKALAEKKLLEDKIDRCISNFKIVGTKKGSDKNVYETK
                     TSVEDFNVEVSSRYQQIEDLIYNYNALDKAINISNAITNVQIGNKNYTVLEAIKRKNS
                     IELDKSLLRQMVSNYDCMMSEVNRRNEEVQKNTDRMFEEKEKSKDGAELISFYKKQQE
                     WSLVDPLKVREKIEKLRDEIEEFEKEVDFALSTSNALTIIDVDLK"
     gene            complement(40280..40370)
                     /locus_tag="ACGI3L_000039"
     tRNA            complement(40280..40370)
                     /locus_tag="ACGI3L_000039"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40335..40337),aa:Ser,seq:gct)
     gene            complement(40938..41216)
                     /locus_tag="ACGI3L_000040"
     CDS             complement(40938..41216)
                     /locus_tag="ACGI3L_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFG9195779.1"
                     /translation="MKKVDFLKEVAEELGVSQIRVREILDVIEKKRNEVLQDGEELTL
                     MGVKYLTKIQKGKEGEITLKDGTKKPWKTEEKRVPKLKIAKSLKDAII"
     gene            complement(41350..42792)
                     /locus_tag="ACGI3L_000041"
     CDS             complement(41350..42792)
                     /locus_tag="ACGI3L_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195780.1"
                     /translation="MIYNNNNFYEEIDGKSAQDYIKNLDYSIDNSKDRIKYIEERLGV
                     KHTWFEESNRNYIDTFYNTLTKRNENIITRVKYQEKKQFNDKFWENIFEQTSDSPLDK
                     DGVYYVTIDGEEVVMDYNRFITWCGYNQINPIEYINVKNPFSNSNGTWEYTHHNTSKI
                     KLILNKDDSIYSTSNIAKTLEIMGSYILSVDDKPKETKIRIYNSKELFDRACQEEALL
                     NKIAPANGGNINSNTSNKDGFLEDNSFAFFQLPKNYKKIKDIKVKPKDIKKYPIIKTY
                     SDTYEWYKAKYKELGHKQLSKEELKLKRMVRKNLNALKNDMTDVKNSIERPIIWKAPL
                     ADAGSPEWDYLDMFDKSHVKELLKIQKGNDLQDDLTCIVMDLNNIISKIEFTTVQKDI
                     LNLYRKDKSLEFISNLMNITPQAINNQINKIVNKIIDAYEKNYEENYYYISVCKGKYK
                     KCSRCGKIKLLSRFDKNGKKGYRSNCKNCN"
     gene            complement(42795..43043)
                     /locus_tag="ACGI3L_000042"
     CDS             complement(42795..43043)
                     /locus_tag="ACGI3L_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195781.1"
                     /translation="MKEKKIELIYLEDLDESEKTGVHKNRYQILNEEYEQMIDTYTEM
                     SKRSSYDIVNERHKEDFKDELWDYDDTDYDDGLQGKEV"
     gene            complement(43221..44084)
                     /locus_tag="ACGI3L_000043"
     CDS             complement(43221..44084)
                     /locus_tag="ACGI3L_000043"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195782.1"
                     /translation="MKRGEVLEIGKRKKSFSPEQRAIINNKKELPYHNFKLGGFVFCT
                     YVKNELLFNEVNISKANISRLIYLATYLNYNTGEENLLVRYSQFKEMIPIDRKNMREI
                     LNLKDRAFRNFLADVKKCELLYESNNKFYINPKYFTKGIPNFENKEYTRIYINTSRFL
                     FEHCTPRQHKQLSYIYQLIPYIHFESNILCLNPHETDISKIKKISLYKICQLLNISTI
                     KQDMNKFKKELLRFYIKVEDDKYYFFKYVIVEGNNKNTDYFIINPCVIWKGNNLNLAK
                     KTIDLCFFNCI"
     gene            complement(44356..44628)
                     /locus_tag="ACGI3L_000044"
     CDS             complement(44356..44628)
                     /locus_tag="ACGI3L_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195783.1"
                     /translation="MKKSSSFYLEEDIFGEIEKYQNDKNISSRNTALERIILEWKNLQ
                     EENKLLKQCLGNGVYRTNKKTNVTEEKKDIKRENPIIKNIFNNMPD"
     gene            complement(44641..45555)
                     /locus_tag="ACGI3L_000045"
     CDS             complement(44641..45555)
                     /locus_tag="ACGI3L_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195784.1"
                     /translation="MEENYQVIGLDIGRGYVKGYSKYNGMVKECLFKSVFGDGRNIDF
                     EKYENPIYIDFESVSYFVGSLAEKESITPIRNSDDSKVSFTMRILVAAALNEIAVADE
                     VKLMMGVPYKSFRKTTLKEVVDTYKGKTFKVKDKIKGGHKEIKISDISIFREGDAALF
                     HTLEGKVNEDKAVGMVSIGFRSTEMSFFEKGFVFNDKLSDTLEAGNQDALTMVQKQLK
                     DRGIIRELNEIDSSNDYDELKKVAYIMASESTAQRISSKWKNIDEMDVYVSGGTALHM
                     TFDNRFKVSKDAQMATAKGLFEVGMEQF"
     gene            complement(45977..46165)
                     /locus_tag="ACGI3L_000046"
     CDS             complement(45977..46165)
                     /locus_tag="ACGI3L_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195785.1"
                     /translation="MESGLFVSRILCVVLSFPHFKKIADGFTDEIALYFPHKTNIYLK
                     IFLRFLLLNYILNKENIK"
     gene            46661..46819
                     /locus_tag="ACGI3L_000047"
     CDS             46661..46819
                     /locus_tag="ACGI3L_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195786.1"
                     /translation="MRITKGKIKELIELCHQLEKLFVQVFKSLEHILISLCSCIGWLL
                     ILIYIIKH"
     gene            47072..47263
                     /locus_tag="ACGI3L_000048"
     CDS             47072..47263
                     /locus_tag="ACGI3L_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195787.1"
                     /translation="MKLEKLIDIRKEKKYSQEDIARMLDISLRNYHRKEKGENQFTVS
                     ELEKICSYLDIESKELLDI"
     gene            complement(47477..47788)
                     /locus_tag="ACGI3L_000049"
     CDS             complement(47477..47788)
                     /locus_tag="ACGI3L_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195788.1"
                     /translation="MNRLRELRKEKGYSTQQVGELLGVHYVTIQNYETNRRKIDNETL
                     IKLSNIYNVSIDYILCLTDNRENIQLEEEEKQLLNNYRELDTKSKTIVQEQVNTLKKL
                     L"
     gene            48520..48822
                     /locus_tag="ACGI3L_000050"
     CDS             48520..48822
                     /locus_tag="ACGI3L_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195789.1"
                     /translation="MDEKILELLQKMDTSINDIQGEIKWINTRLDVMESDIKDLKTGQ
                     VEIKDDLKEIKGDILKLDLKTEDTRRNIKLMQLDINKIETITNYNLNDIATLKAIK"
     gene            48917..49105
                     /locus_tag="ACGI3L_000051"
     CDS             48917..49105
                     /locus_tag="ACGI3L_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195790.1"
                     /translation="MYEQRKAKVIFNKGAGNSRGESYTNRVTIPTTWIKHMDITKLDR
                     EVLLTFDGNKIVIEKIDE"
     gene            49227..49940
                     /locus_tag="ACGI3L_000052"
     CDS             49227..49940
                     /locus_tag="ACGI3L_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFG9195791.1"
                     /translation="MLNIYITNLGKYNEGELIGEWAELPINEEELQEILDRIGINEEY
                     EEYFITDFETDIEGLEISEHSNIEQLNELAMKLERLEEYEIEELKALLERGYIDFYDM
                     IESDICSLSDNYTFIQLDDRSQLDDENLGRSYIEEIYCGDLSYIENIAYYFDIEAFSR
                     DLRFDKDMIIENLYEEDIEYYENMTDIEFAENYIERLGDIEELGQETLERYFNYELYG
                     TDLRYENICIASNYLAIVS"
     gene            50008..50148
                     /locus_tag="ACGI3L_000053"
     CDS             50008..50148
                     /locus_tag="ACGI3L_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195792.1"
                     /translation="MKKLIIKIKSLFKKDLDSSYWSTTESIILKCGNSNQLELLKQAN
                     KL"
     gene            50161..50397
                     /locus_tag="ACGI3L_000054"
     CDS             50161..50397
                     /locus_tag="ACGI3L_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195793.1"
                     /translation="MVNYSEYMTATDLINICDLLEGKIIGEAGTYNSLYVRLGNLIGL
                     DWALKGGELRQQLIQNINNMMYLDNKNKMQYKEF"
     gene            50432..50728
                     /locus_tag="ACGI3L_000055"
     CDS             50432..50728
                     /locus_tag="ACGI3L_000055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195794.1"
                     /translation="MKKIINGYSIYKDGTWCEVIKEGKFIFAGSVNEKLSYEDIYIAL
                     TAKLEFRLHGKLLLSYSLYGTFQGEKQSTLELLAYENNCNINDIEVKQVVENIQ"
     gene            50865..51410
                     /locus_tag="ACGI3L_000056"
     CDS             50865..51410
                     /locus_tag="ACGI3L_000056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195795.1"
                     /translation="MKKIANLNKEELKIIWEKNSQLREDVRKACEDNDMYWIDEILCH
                     LNKSLDDWSIGFYNDNYIKIEDNHKFLLELKSVCEKFSFLSEEEQRPLEYAISLIDKL
                     HCMDFENKRFNMLENKINNMVKKLEEKVIEEFNKMTEPLDKEYLLENFIEFYVEAYLN
                     DNEFYIDNEYVLYEKIIKSYA"
     gene            51436..51699
                     /locus_tag="ACGI3L_000057"
     CDS             51436..51699
                     /locus_tag="ACGI3L_000057"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195796.1"
                     /translation="MLANQIKGIKTSLETSSLRELKGYIKDLRKALSGYKYKNKIDEI
                     TEYQIDKLCYKIDNTDIFDLKYKEIEKYIDSLILILDFIFMEM"
     gene            51737..52321
                     /locus_tag="ACGI3L_000058"
     CDS             51737..52321
                     /locus_tag="ACGI3L_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195797.1"
                     /translation="MNEYILISYTKGEGTCDHCGRTIKNIATIKNNVTGEVFHVGLTC
                     VEKIMKLNVTFYKALSREIKKHYKCMEYYSKGLDIETNLNKIVKNNTKYKEGSYAYKS
                     NEQMLEDAIAEVAWSLARMIDSCMRMNKLSKSGLIDIDILNSLFIKYKEYMSKFDENY
                     NKNKYKYKSCYTMKPLKVILDENEDLKELYKSMQ"
     gene            52625..53146
                     /locus_tag="ACGI3L_000059"
     CDS             52625..53146
                     /locus_tag="ACGI3L_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195798.1"
                     /translation="MKFKNIVMGMLLGLIIVGVSGVTKVKAAELDNFYIESTDRVIEV
                     LEDESIVLYDTKEQVYNFYPICMGDWNYSFKNKKDLDSAVATYKELSSNINHLSNIYV
                     VNKLNDNGNIKVFLNDGSSIVYIKQDNKYYFYPSCMGDWYLTLDSKIYLTNCINTYIE
                     YYYSLSTGGGTNE"
     gene            53139..53369
                     /locus_tag="ACGI3L_000060"
     CDS             53139..53369
                     /locus_tag="ACGI3L_000060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195799.1"
                     /translation="MNNNDKLSILNQLEYIENDIDARNEMIEKFKDLLVKYPKSRDIR
                     RYIKQQTQFLNGIRYIYDNLDILKNMINNDKK"
     gene            53540..54349
                     /locus_tag="ACGI3L_000061"
     CDS             53540..54349
                     /locus_tag="ACGI3L_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFG9195800.1"
                     /translation="MNKLKVKGKQKFMNLEIPVIEGGFGEDKKCMTDKTISEIHNQPN
                     FKIRERIKDNIKRFKEDIDYIDLKVIRDTDDNLELLQTLGYSKMQISKADNIFLLSER
                     GYSKLIKIMDTDLAWEIHDKIMDEYFSMRKKLNDPFENLSPELKVIIKLEQRQAELES
                     GQHELEEKVNVLYDFSTIDYNQQETIRSLVNRMVIQVYQCLNFSAYEDAKLRKRVYFS
                     LWKDYRKKFGVNSYKNTAKKNYDNAIKFIENWEPNYDLSNEIYMFQKVENI"
     gene            54636..55343
                     /locus_tag="ACGI3L_000062"
     CDS             54636..55343
                     /locus_tag="ACGI3L_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9195801.1"
                     /translation="MIENKFIEKLKYTKNIPNSLYKDLRHNFLFHSNKIEGSTFTSES
                     LQDLIEHNIVKGDHTLDDVITTVNSSYVFETVIDTLGEYLTEKYIKDLHGQLMYNSNI
                     HNMGLSGIYKKIPNRIIGTNSVLAQPFEVEPKMLELIEWYNNLKDITLKDLAEFHYRF
                     EIIHPFQDGNGRIGRFILLKQILENNLKLIIISSDTVDDYRQALKGCHNEYYKPLEQY
                     FESLDDYKEKNKDLWSF"
     gene            complement(55585..55884)
                     /locus_tag="ACGI3L_000063"
     CDS             complement(55585..55884)
                     /locus_tag="ACGI3L_000063"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195802.1"
                     /translation="MVIKVNFGGNYSPDYIYVPNEISLKKYEIRNEFHIWIDNTEDEH
                     PFWCYENGVQIGLHYRGDAIVYWLNNYILKNANDKARLIESFSNKKLDYDLIINL"
     gene            complement(56080..56262)
                     /locus_tag="ACGI3L_000064"
     CDS             complement(56080..56262)
                     /locus_tag="ACGI3L_000064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195803.1"
                     /translation="MLKTLFILLAVFVIIKLSILIFKDALKFLNMFESKNESFIGWLF
                     LCILALVIYNLIDIIL"
     gene            56458..57030
                     /locus_tag="ACGI3L_000065"
     CDS             56458..57030
                     /locus_tag="ACGI3L_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFG9195804.1"
                     /translation="MTWNDLKNNDITYIVEYINNKLNNSKSLTKVAIGLGVSESSIRK
                     YLTKRGYKRINDEYVFIGDNSMTKVVNNRQQSNNDNTFNMTIEDDNNHNIVIDNQFKN
                     NIVSLAKDYDKIQDVLNWFENKEDTNVIEVVQDGIKIDLHSKDAIRTTVRLNKDAWNL
                     FDEFCGKFREFNKSDLMSMALLEYIKKYDK"
     gene            57163..58089
                     /locus_tag="ACGI3L_000066"
     CDS             57163..58089
                     /locus_tag="ACGI3L_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195805.1"
                     /translation="MNYNLKNENVLSELLQNEDEKTRIGILKVYKVLIFWFAKEGKLV
                     EEENDYIVEIVGNDKEEIVRDMSQNKTYNAIMAIIFKINKIFKTLNYDIHFSKPKNLV
                     AEFDLSKYLTQDEVLQVCSKLTNAQDKFIIYAAFCGLIGKDAEDLRGIKIKDIDLEKR
                     LIKLKDTEFKLDKFLFDFTKDTLEQKEYKQYLEQDSNAAEFYLFNSNSEYLIKTKPDA
                     RYGNGLKEMGYSTIRKRLLIINDYLDNKVQLNFTNLKISGIMHQMHLNEKKYTQSGYW
                     TNKSLKEFKEDNNLNFKIQEVLSIYKQKYIKE"
     gene            58094..59662
                     /locus_tag="ACGI3L_000067"
     CDS             58094..59662
                     /locus_tag="ACGI3L_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195806.1"
                     /translation="MSKDVKENISNEQKDLNKINLIYHIIYDNDRFKMITRKYFEIFR
                     LKGMSAEEISLKFEEFLYSLISDKFKKINTVNDVKKLRNQENSSSLKLKKRWSDMTLD
                     SLSEDTKSSRKKSSKYLKKELEIVESEYLKNGRIISAGVKNPKELKEQRKDFLDEWKS
                     SSSYNICDYPYLQELSTSKINSAFIHDILMCITEVLKDDYDFDINKIAIKTPPHISPG
                     IFLPFTKGKRYSHLNVKKNENEYMSDDYSAKNLSGKQMNFFYKFSIGQDENIENLKLE
                     LINPDTEKRALPKIYLDKQDLEIIRFVYTYSHMNSFSFYLGDLVKYLGLSDGKKNYIN
                     IKNRLLKLPYYTFYSNQTNDKGELKYEISFNLFSSTTIVNDENNNNRELVKITKSFIE
                     EVERVNTDIMYRNELEKLQLTQSINLAYFLEGRRSFLISCGEDIKNKSFRYDIEDLKF
                     DVHLNKSKTVKQNMEYLELGFNEIKENQFIIKDYKRGNSYFDVYFYEDFEKRKRLINN
                     TILSLPDYMIENKS"
     gene            60136..60402
                     /locus_tag="ACGI3L_000068"
     CDS             60136..60402
                     /locus_tag="ACGI3L_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HFG9195807.1"
                     /translation="MSLKYKDKEFVLVEKKNINELDNSNIKYIDLKDKQYYVVTQGKK
                     PKRFNLEDIKNIKKDLDNGISLRKCATKWNCSTRTIQDIKNNIY"
     gene            60478..61656
                     /locus_tag="ACGI3L_000069"
     CDS             60478..61656
                     /locus_tag="ACGI3L_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195808.1"
                     /translation="MQELKPVARISKSKLKDILDVFKTSIRKVEKIDYSACNSCAIKN
                     NPSFDSHKLNEFCSNCPKLKTISEFSYVTEKETELGTIEIVTNESKCMALSKSAIKQY
                     LAYHFIVSNKNYVRKAVSFQNIADICNVSIVTARHNHNVLLRVGLVYSTEIKRGKFDI
                     VIDEEYKNHLKKEDGGKGYLTMSLDTLNHLLSFENVNELKLEIKKLIWADAKGSKLGK
                     RIRFKKDNLISILPEYIKKSNKRTEAFLRSSKTLFDVSNDTIDTKRYETKETISEKYT
                     EPIRIQISKFFDNTGCSLSSNYSKVLSQINLDRYNLFEEDLRSKLDMEKDIIINDLVG
                     LSVQYGVTRVLAALDYMFNKYTFDEEDINYNEIRNPGAFIRTLIVQSINKNGSLAIAI
                     "
     gene            62418..62558
                     /locus_tag="ACGI3L_000070"
     CDS             62418..62558
                     /locus_tag="ACGI3L_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195809.1"
                     /translation="MSEGKINKEKLMKLGNMLSELKRNNKDKFTNYKSEVEKYENKKR
                     GA"
     gene            complement(62569..62907)
                     /locus_tag="ACGI3L_000071"
     CDS             complement(62569..62907)
                     /locus_tag="ACGI3L_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195810.1"
                     /translation="MNKRLKTLRKELGLNQTQMGNKLFLSQDHISSLETGRRDLTDRI
                     INDICKEFNVNENWLRTGEGDIFQDPTLDMDFDDDIKEMLRMISKLSPEAQKRLYNVA
                     EVFLEEENKK"
     gene            63070..63225
                     /locus_tag="ACGI3L_000072"
     CDS             63070..63225
                     /locus_tag="ACGI3L_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195811.1"
                     /translation="MHKKKMNQKELELLGKMFLKIKKIDKQKFGELKGSVKTSLEYEY
                     ILVNKIR"
     gene            complement(63381..63713)
                     /locus_tag="ACGI3L_000073"
     CDS             complement(63381..63713)
                     /locus_tag="ACGI3L_000073"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195812.1"
                     /translation="MYTRVKQIREKLKLNQAEFAKKIGLSQSTLAMIEVNKRTFSDKH
                     IKLICSEFGVSENWLRTGEGDMFASSPYEKEFLNIFDSLTSDTKEYLLLMAKELLKTQ
                     NKLLNSKK"
     gene            63877..64020
                     /locus_tag="ACGI3L_000074"
     CDS             63877..64020
                     /locus_tag="ACGI3L_000074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195813.1"
                     /translation="MEDIITTEMKNTFLNLSVNNQLEILNLAKTIKKIEDALNIEDNE
                     NYN"
     gene            64051..64845
                     /locus_tag="ACGI3L_000075"
     CDS             64051..64845
                     /locus_tag="ACGI3L_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFG9195814.1"
                     /translation="MNNLRIKGKQKFIDLEIPIIEGGFGESKKCMTDKAISEIHNMRN
                     ADIRRRISDNLKRFKNNIDYIDLKRVHETHTLIELGYSKQSITQADNIFLLSERGYSK
                     LIKIMDTDLAWEIHDKIMDEYFNMREQLTDSYMIQDSIERAKRWIEEEKERLLLKETI
                     QVQQPKVEYHDKVLNPDKLVTTTDIAKDLGMTAQALNKLLHLNRIIYPERINGRIKCW
                     KPYKNYLWLIPEYADFKITEHDTQLKWTEIGRKWLIEFVENIKKIS"
     gene            64909..65133
                     /locus_tag="ACGI3L_000076"
     CDS             64909..65133
                     /locus_tag="ACGI3L_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195815.1"
                     /translation="MIKQILNKRGSLLNLASEYLTEQDYLKFQGWYTHRYSKMDAYDA
                     SINEYLNYKNDKKLITYVFNLKFQEALIEI"
     gene            65157..65693
                     /locus_tag="ACGI3L_000077"
     CDS             65157..65693
                     /locus_tag="ACGI3L_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195816.1"
                     /translation="MNYNYVTKIDLKYGNTQFGFEKYSDALDKYRELKEEFKYVPCII
                     KLHSYVAHQDLYVKEIKADGFEKKYLDIKNLIKLFKEHKQNISDELSLCDKKKEEVLH
                     VIEEMNLDTASLNDKIDTIKELKNTLAKRRLVKYELNKYFAFCNTLYEIEEELKKYES
                     KYKQKENQGKSRFKKNKK"
     gene            65702..65842
                     /locus_tag="ACGI3L_000078"
     CDS             65702..65842
                     /locus_tag="ACGI3L_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195817.1"
                     /translation="MEEYYFNLIKKLCAERKIHKGWFRNIEKCGCGGKCNKKNCKMLE
                     KL"
     gene            65853..66086
                     /locus_tag="ACGI3L_000079"
     CDS             65853..66086
                     /locus_tag="ACGI3L_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195818.1"
                     /translation="MENQIELTEKDIENTLSALNIIKYICIKSKHCKNCPLGYMKNLD
                     EHNCMLYELIDKGLLPCDWSVKKVTRLLDTTEE"
     gene            66105..66392
                     /locus_tag="ACGI3L_000080"
     CDS             66105..66392
                     /locus_tag="ACGI3L_000080"
                     /inference="COORDINATES: protein motif:HMM:NF021182.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFG9195819.1"
                     /translation="MELDFRIWNGFRMIHGEELRLLTEEMFIKSGYSEQYYNDICIPR
                     VEDLKIMQYIGLKDCFEKKIFQYDIVKFIFDGVWKVCLVNLSLPKRSNSYI"
     gene            66529..66723
                     /locus_tag="ACGI3L_000081"
     CDS             66529..66723
                     /locus_tag="ACGI3L_000081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195820.1"
                     /translation="MDEMIIRVKMGEPLPTLGKIIKCTTCLTNEEKCFKVNKICKLSW
                     INDRNSEGLIVECKGKYIKY"
     gene            66930..67484
                     /locus_tag="ACGI3L_000082"
     CDS             66930..67484
                     /locus_tag="ACGI3L_000082"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003950 - NAD+ ADP-ribosyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HFG9195821.1"
                     /translation="MSKKDKLSIFISLILRHKPETIGIKLDDYGYADVNELIEKINNT
                     GRNINIEILEQIVKEDNKQRYSFNDDRSKIRANQGHSINVEVELKELEPPKCLYHGTA
                     TRFLENIKKEGIIRQSRLYVHLSNDIDTAVKVGKRHGVPVVLKINTGKMYENGYKFYL
                     SENNIWLCKYIPFEYVEKISRVVK"
     gene            67511..67837
                     /locus_tag="ACGI3L_000083"
     CDS             67511..67837
                     /locus_tag="ACGI3L_000083"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195822.1"
                     /translation="MDFNFRKICEKDELTDDFIIKICQLSHEEFGGTIYVPCNIHPCG
                     WDELEVPNPKDLDSDKLMEEFLLEYKFECENISSNIYDSDHPFIGKTLREILMIVDCR
                     FIIGVI"
     gene            67852..68628
                     /locus_tag="ACGI3L_000084"
     CDS             67852..68628
                     /locus_tag="ACGI3L_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195823.1"
                     /translation="MENIELTPRDYFEDIKNKKQKNTNENLDIVYENSLILLNKYIVT
                     GQKKGAKKLMFLLECIEKERNVIELGIDTFVYKEDIEKYIDDISKNTVKIIELENYER
                     EIPDEIVEIIEKTKDIFDKMYVLFTDYTGKITKEISKERRDKDPILFGVFSDEKSRAI
                     VDRFYYLGDWEDEYCDLTLEKMINDYKKKGRQDILKHIITPKSLDELKKELDSLEKNN
                     DTYKQVANIKPLPTTKNSSVEPPKLNIFKKIKNRVFKNEK"
     gene            68618..69019
                     /locus_tag="ACGI3L_000085"
     CDS             68618..69019
                     /locus_tag="ACGI3L_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195824.1"
                     /translation="MKSNVDLTENRDFRDVRGRGINILGIEDAPNRMLSFSDFGIGRL
                     YGKNLEFEFNKNEVFLTGNANDREEKKFLILCEENKVCVRCGDELREGWDKVSIELCN
                     ECYEMLDVEYKNKKIIRELFFRDRDVNIELL"
     gene            69208..69528
                     /locus_tag="ACGI3L_000086"
     CDS             69208..69528
                     /locus_tag="ACGI3L_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195825.1"
                     /translation="MFIKSFRCIFRHKFSRIKDCQLITTRSQQYTCKIWMCKYCGQIV
                     AGSTPVYHPNMKVNEYCVKCEFSACANNYEGYCNSKDKEIEFKSICLKGNKEILQCKN
                     FDLE"
     gene            69559..69744
                     /locus_tag="ACGI3L_000087"
     CDS             69559..69744
                     /locus_tag="ACGI3L_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195826.1"
                     /translation="MKINVHVKTNKIGSDCELEFEIDDDDLKDMSDEEREDYIDKIAW
                     DYVFENFIDWNWYEVED"
     gene            69787..70734
                     /locus_tag="ACGI3L_000088"
     CDS             69787..70734
                     /locus_tag="ACGI3L_000088"
                     /inference="COORDINATES: protein motif:HMM:NF013623.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195827.1"
                     /translation="MNKDNLETIIEGYKVFNPDWTCRNFKYEVGKTYEHDGDIEVCEA
                     GFHFCQKAIDCFNYYSFDNKNKVAKIEAIGLIKTDGDKSVTNKITIVKEIEWEELLNI
                     VNIGNNNTGYGNTGNHNTGNHNTGNHNTGYRNTGDYNTGNGNTGYRNTGDCNTGYRNE
                     GNYNAGNYNAGYCNTGYCNEGNYNTGNYNSGNCNSGDWNIGDYNSGVFCTDVPKIRMF
                     NKETDLTYEDWMNSDARNILKRNSYLTKWIHIDDMTEEEKENNPGYEINNGYLKVFIF
                     EEMCKNMWDSLTEEEKKIIIEIPNFDADIFKEITGIEVI"
     gene            70858..71490
                     /locus_tag="ACGI3L_000089"
     CDS             70858..71490
                     /locus_tag="ACGI3L_000089"
                     /inference="COORDINATES: protein motif:HMM:NF019481.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HFG9195828.1"
                     /translation="MAKYDLLLKLNNILFKMEKHCDEMIKNNNDKELRTCTNCEFAYY
                     GSYVESGCVCTDIEGFGIHDMVKRIIEKNKEKIDLERKIKYPAIYKHFKGGFYTVMGI
                     SKAVTGDELDNIFKNMGCINRLDVLEYRFGSRHTETRHTETRENVIIYRDNKGNLYHY
                     KDVDNNTNLVIYKTLYDGTGAYARPIEMFFSKIDKEKYPNYTQKYRFEEV"
     gene            71493..72605
                     /locus_tag="ACGI3L_000090"
     CDS             71493..72605
                     /locus_tag="ACGI3L_000090"
                     /inference="COORDINATES: protein motif:HMM:NF023645.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidoligase family protein"
                     /protein_id="HFG9195829.1"
                     /translation="MPTFNRYRIEDLSGLQNERWRSEDSRNICLADWIPGNISHNSNP
                     TIVDQFNDELGGLANEFTQWNMGDFFAQFTPIKKVKIGDVARKYLNPHYYIPDEFNFN
                     NITNDESLYLGIELEVDNGGKSEENAKFIQEFLGEKNCYIVGDGSLLDGLEIVTHPCT
                     LQYHKKLEYKDLFEELKEKGYKSHDTSTCGYHIHINRDFFSSDLTIQDLCITKILYLI
                     EKYWKYVTVIARRRSNQYSKRFGIKDNESMFELLIKAKGSYVSKYNVVNLQHSKTIEF
                     RMFRGTLKYETFIATMEFVHNLAYICKDTSLEDIQNIEFQDILNVYQTEYLLLYFNNR
                     IENMNNTVDLEDEYKENLRRRIFIRDEWSLFHESLM"
     gene            72672..73682
                     /locus_tag="ACGI3L_000091"
     CDS             72672..73682
                     /locus_tag="ACGI3L_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFG9195830.1"
                     /translation="MDIKSRLESKEYNFLREEERLKNRMILPPIVRSFAYGTNIDTPE
                     HISDLDIRGIYLNSVQEILTMNCINKPYENKQTDTVIYPLKQIITLLLNVNPNVIEIL
                     GTRKEDLFVCTEEGKLLKDNVDLFLTKRAANSFGGYAISQLRRLQNALARDNYEQKEK
                     EEHIMNSVKRQMKTFEDRYKVVSEEEIKLYIEESKRTDLEEEIFIDVNLRKYPLRDLK
                     GMWSEMNNILKDYSKLNHRNNKKDELHLNKHAMHLIRLFLMGIEILEGKGINTYREND
                     KEFLLDIRKGKYTYNEIFEMVNELDKNFKYAEKNSCLPNSPDMKKVNELVMYMTNRVL
                     NR"
     gene            73832..74182
                     /locus_tag="ACGI3L_000092"
     CDS             73832..74182
                     /locus_tag="ACGI3L_000092"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195831.1"
                     /translation="MNINKLKKIKERKTKRWNIEKITNRINDHMNIQEDIEKWDKFET
                     PIISKEVDFYLLKIGFQYGRNNGRNVLVGIKDMRHISISKVNSNLLSIDIYKFIKQED
                     GKFSEFKAHEYIEK"
     gene            74236..74637
                     /locus_tag="ACGI3L_000093"
     CDS             74236..74637
                     /locus_tag="ACGI3L_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HFG9195832.1"
                     /translation="MKELLEVKKIFDSLASTSSRKEKERILEKYKNNRMFVECLQFLL
                     DSNILTGISKNKICKNLNNTGHNELENIYDMLDYLIKNNTGRNIDVKTIQVFASKDEK
                     LKDFIFNLATKSIKLGITYKTVDKIMPGLII"
     gene            74737..75240
                     /locus_tag="ACGI3L_000094"
     CDS             74737..75240
                     /locus_tag="ACGI3L_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195833.1"
                     /translation="MTDKIIIASVDGEEMIFRTEMKKLEKGDSLIVSVNGVKRLALFI
                     RYISTCEEYIEDIAFQKVDEILYENTIAKEKERVKKVFKDKCMKNYKPIVNTEIDSYL
                     RECGFNCDGRQFFKSIDNTQILISRDCDKDVLTVSKGLTITKTDITNKNLITVIKIIN
                     NSLLIVR"
     gene            75300..77525
                     /locus_tag="ACGI3L_000095"
     CDS             75300..77525
                     /locus_tag="ACGI3L_000095"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HFG9195834.1"
                     /translation="MKNVIKRDGRIVPFDEKKIINAIEKSFLSLRNKGKSEVFDRELA
                     TLIAKKIKNKPCEKMHIEDIQDIIEFSLMASKKKDVAKEYITYREKRNIARGRKTYND
                     YMSIVNTESNDITKENANMNADTPAGMMMKFASEATKTFTDHVLLSEEAKEAMMDNYI
                     HIHDKDYYPTKSLTCIQHPLDKIFNNGFRAGHGSSRPTKRIETSSILGCISLETVQNE
                     MHGGQAIPAFDFYNAPSVRKTFIEEIKNIEIKDDIDLSHLYNIEIEDYIIKDLKELDS
                     EKRNVQHAINRTVWRVHQSMESFIHNMNTIHSRGGNQVVFSSINYGTDTSAEGRCIIR
                     EILKSTYEGVGNGETPIFPIQIWKVKEGVNYNPTDRNYDLYELACKVSAKRFFPNFLN
                     LDATFNKHVKWKMCDPNRYIYEVATMGCRTRVFEDLHGEKTSIGRGNLSFTTLNLVKM
                     ALEAKEKYPNNEANRVAEFIFLLDKYSDVVARQLYDRYLFQCTAKAKQFPLLMSGLWK
                     NSENLNPNDDVSEVLKHGTLGVGFIGLAECLIALIGEHHGESEKAQKLGLEIISLLKS
                     KVEKYKKKYNLNYSVLGTPAEGLSGKFTQKDKKIFGEIKNITDKDYYTNSSHVPVWYN
                     CNVEHKAKIEAPYHELEGGGHIFYVELDGDATHNPKAIMKVVDLMKKYNMGYGSVNHT
                     RSRCMNCGFENADSELKECPKCGSNSINIIQRITGYLVGTTDSWNNAKLAELKDRVTH
                     G"
     gene            77518..78015
                     /gene="nrdG"
                     /locus_tag="ACGI3L_000096"
     CDS             77518..78015
                     /gene="nrdG"
                     /locus_tag="ACGI3L_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFG9195835.1"
                     /translation="MDKDYIYILDIKHDTIVDGEGFRTSIYCSGCNHMCRGCHNPQSW
                     DIKNGTLTKVLDIYKEIISNKFSDVTFSGGDPLLQLQGFVHLAKLIKKNTNKTIWCYT
                     GFKFEELITDNEKLELLKLIDVLVDGKFEEDKKSLELIFKGSSNQRIIDVQKTLYEKQ
                     IVLYE"
     gene            78050..78181
                     /locus_tag="ACGI3L_000097"
     CDS             78050..78181
                     /locus_tag="ACGI3L_000097"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195836.1"
                     /translation="MTKEEFITKFLKEQQRRIKVLYYEVENFKMDRRFNERKKSRRH"
     gene            78216..78623
                     /locus_tag="ACGI3L_000098"
     CDS             78216..78623
                     /locus_tag="ACGI3L_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195837.1"
                     /translation="MYFETDIIKNKNTVNKIIKYCGGNTEKLKDWLKEIENKSISSLE
                     ELKEYPLKRNYKFVFSKEEAPNLDKLIKMKLRDNCLEKCEICSLENLLSMLNDEILDL
                     NKEDISYEDNIEWIENCKEELIKLKVGSICIDW"
     gene            78644..79180
                     /locus_tag="ACGI3L_000099"
     CDS             78644..79180
                     /locus_tag="ACGI3L_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195838.1"
                     /translation="MRFWCENCNKYFNAEETLQEYNYFLNEDIIVCPSCKKDLIPIAR
                     ETELSLGFDSDTNQLTYVEYDSSDYSLLRKVNADVEDVVKPIIHYIRNLNKNSLDLNG
                     ITITMNGNREGKRLDGLNYEEGVVMDNLINAWNGFCKLKRQHPSELGDFQNAIHQAQQ
                     VLGLRVLRNDYPKGWIKK"
     gene            79201..79599
                     /locus_tag="ACGI3L_000100"
     CDS             79201..79599
                     /locus_tag="ACGI3L_000100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195839.1"
                     /translation="MSTKTILKNIDIKDDKAAERLISALEESENKQDSDWDIKKMLEL
                     IDNLPCPHIIYGTPKALSKLENILNILKIDKANSHHVQNFIEVPVRDLSEYCNYENNK
                     SLFDDSVLYIVPRGTKLKVYGGEYRHVTLK"
     gene            79633..79803
                     /locus_tag="ACGI3L_000101"
     CDS             79633..79803
                     /locus_tag="ACGI3L_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195840.1"
                     /translation="MTKYKIEDRTNLIIHQSKKYNVKFILIPENEDKREMLKKVLRCL
                     KKERIVFLLKVS"
     gene            79941..81983
                     /locus_tag="ACGI3L_000102"
     CDS             79941..81983
                     /locus_tag="ACGI3L_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195841.1"
                     /translation="MEFNNFKKQVQERFNKMTTGISYIYEVDLDKDRLWNLYLDSFPE
                     GTNEIFRERREYDCSCCRQFIKNIGNVVTIKDNKISSIWDIDTDCPTFKPVVKALSEY
                     VKSHNINDIYVSKFKKIGTDKNFENTSEKVYEWNHLYIELPDRFVDKTNKSVGDIKGR
                     IRDVKNVFKRSLDEISEDSVSIVLDLINQKSLYKGEEWQNPLIEFLKYKRNYIKLQTE
                     TDKQNFAWEQSVKAGVVIGKMRNHSIGTLLLDISEGVELDKAVNRYEKIVAPSNYKRP
                     KAIYTKKMLDEAKKTITELGYMDSLQRRHATIDDITVNNILFVNKDSAKQMGEFDIFD
                     EMSKGIGIDSKKFSKVEELNIEEFIQNVLPTSKEVELLLENRHIDNFVSLIAPVNKDA
                     KSMLKWDNNFGWAYAGNMTDSSMKENVKNAGGKVDGVLRFSIQWNDTEFDNNDLDAHC
                     IEPNGNHIYFGNKTNYSTTGMLDIDIMHPKRGNVAVENITWSDINKMRLGTYKFYVNN
                     YSKRSGISGFRAEIEFNGEIYSFDYNKPLRDGENVMVAEVTLDIGNRFKIKPLLPSNV
                     SNKEIWGLTTNQFIPVSVIMNSPNYWDGQQGIGNKHYFFMLKDCINEETVNGFYNEYL
                     KNDLNVHRKVFEALGSKMSVPFSENQMSGLGFSSTRRNEVIVKVRGSYERILKIKF"
     gene            82006..82386
                     /locus_tag="ACGI3L_000103"
     CDS             82006..82386
                     /locus_tag="ACGI3L_000103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195842.1"
                     /translation="MENVFEMATRNKFRFEFRGLISVEDLWDLKLEQLDEVYKTLTTD
                     MKKANEESLLKIKTKDQKEVELKIKIVKYIVELRLAEIENRNKEKKKKEQKQHILELI
                     NKKENQELENKSIEELKSMINSLE"
     gene            82464..82685
                     /locus_tag="ACGI3L_000104"
     CDS             82464..82685
                     /locus_tag="ACGI3L_000104"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195843.1"
                     /translation="MDSKIEVGSIWGLEDWIAQPQYVGTKVKVVSISYIEEFNKRLIT
                     FMEIEEKEEDTWIDADWEDVFLNDFFKLD"
     gene            82736..83059
                     /locus_tag="ACGI3L_000105"
     CDS             82736..83059
                     /locus_tag="ACGI3L_000105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195844.1"
                     /translation="MNNKVLIHLTNGAIVDITTEQGYSSGCETCDYGTRYITDLMIIY
                     KNKKKDIIRDESMYDYGISLSSIMKVILNHQEDIEKLKEEEVAEFIKNKLENEHDCDE
                     LKIFN"
     gene            83175..83525
                     /locus_tag="ACGI3L_000106"
     CDS             83175..83525
                     /locus_tag="ACGI3L_000106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195845.1"
                     /translation="MCKFCDSIKDMKKHETRRVRISSVGIKGKDTTYESIELLDQEEY
                     FDISFYKFKEGNINLSVEHNLIVKDSNQNIKLNVDRFAGGIPFKYCFLCGEKLSSESI
                     DFENYIDNLMILEE"
     gene            83717..84184
                     /locus_tag="ACGI3L_000107"
     CDS             83717..84184
                     /locus_tag="ACGI3L_000107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195846.1"
                     /translation="MFDMIINKEIFKYNNENIYDTLINSFSNETHEDDIKQGETIIIF
                     TTNKQLVYKELIRAAIKNKYTLIKHRNRIKHNIEIELKVLNTDRLIKFLIFDRDINYQ
                     ELRGYRGECVIVDVNTSNKTIQNFITEQIKLVLLFMNVYKKEYKPFHGVLLFK"
     gene            84204..84563
                     /locus_tag="ACGI3L_000108"
     CDS             84204..84563
                     /locus_tag="ACGI3L_000108"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195847.1"
                     /translation="MNINTNYVSTNMIVMDISKGHNIEITKAMVEKSIHTFKNAPVIY
                     NPNQELSDYRDADRVNDFCKDEVVGIIMDVAIVDNQVIGKILWYDNCHIKEKYDNWYI
                     SLSDDKSEFILKGVEIS"
     gene            84616..85869
                     /locus_tag="ACGI3L_000109"
     CDS             84616..85869
                     /locus_tag="ACGI3L_000109"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HFG9195848.1"
                     /translation="MEIKGKYNKAKIFTDNVDSTTISQIINLCNQKEFKESSIRIMPD
                     CHAGKGCTIGTTMTISNKVVPNLVGVDIGCGMATIPLEKYINNINYTKLDKIIRDYIP
                     HGFKIHNKSREKLLKNLFNIDINNLRCEVNKNRAYMSLGTLGGGNHFIEVDKSEKGQM
                     YLTVHTGSRNLGKQIADYYQDKAIKYCIEKYKKSYDDAKEFLISTLKKDNKEHLINKY
                     LKDLSDRKLNKPHDDLCYLENDLMEDYLHDMSIAQKYAAANRMVIIADILFKYNSLDV
                     NYDHFIRDIKCDVIECIHNYIDMDSKILRKGAISANKDETVIIPVNMRDGIILGKGKG
                     NSEWNYSAPHGAGRILSRGKAKEKISLDEFEESMKEIFTTCVGQSTLDEAPQAYKPIE
                     NILNNIGDTIEIMEVLKPIYNFKSN"
     gene            85911..86813
                     /locus_tag="ACGI3L_000110"
     CDS             85911..86813
                     /locus_tag="ACGI3L_000110"
                     /inference="COORDINATES: protein motif:HMM:NF013528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFG9195849.1"
                     /translation="MIKLITHNDLDGVGCCIIAKYILREQIDVNYCNYKNINDVVLDT
                     LKNHDKYEQILITDISVNEDVAKKLDRIKNKVQLLDHHPTALFLNNYDWANVEIECNK
                     GKTCGTQMLFNYLQRCYDDTSESTLKYFIELVRRYDTWEWKDKYNDLDAKYLNDLMYI
                     MGIEDFIMDMLTKIDSDEMCLFDKLSLKLLEIKQKEIDRYVEKKDENIMVKEILGYNA
                     GIVFAENHISELGNKLSELHPELDFIVIINREIISYRTIKDNINLSEIAKVFGGGGNP
                     KASGSQIDESCIDNYIKDIFNIKS"
     gene            86921..87199
                     /locus_tag="ACGI3L_000111"
     CDS             86921..87199
                     /locus_tag="ACGI3L_000111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195850.1"
                     /translation="MMIDKFNYELYNEFPHLSPIIELYNLNIEYIREVVSILINTDMT
                     FQRFKYSKSRVECSMKAYIISPNSKLSVVFAYDCELNGIDLDNLKAII"
     gene            87246..87656
                     /locus_tag="ACGI3L_000112"
     CDS             87246..87656
                     /locus_tag="ACGI3L_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195851.1"
                     /translation="MCKFCESIIDNTKDILLTSRSRLLEDNTCEIIAEDNCNNCYDGC
                     YEYFKLNGYKSRGNIYVNIDYYKNIRKIIVAPCSESVHINYCPYCGKQVSKDIKDFNC
                     IPGHIVDVRYKNGDVYDYDMEKSVQEVMDNANNN"
     gene            87687..87860
                     /locus_tag="ACGI3L_000113"
     CDS             87687..87860
                     /locus_tag="ACGI3L_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195852.1"
                     /translation="MNLWSKIEEPVMRAVGGIVFNIWGNVCFSIYYIEENKQIELEIY
                     DRPYRYEGKKNSC"
     gene            87970..88113
                     /locus_tag="ACGI3L_000114"
     CDS             87970..88113
                     /locus_tag="ACGI3L_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195853.1"
                     /translation="MNKGIKNYITAVNYLLDNLEYMMEDDEFNNEKLQKRIDVIRKFE
                     REL"
     gene            88115..88420
                     /locus_tag="ACGI3L_000115"
     CDS             88115..88420
                     /locus_tag="ACGI3L_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195854.1"
                     /translation="MGKIKNGEIDTEDYRLFKNIQKEKDRVYSKYINEEYIMEEFINY
                     LRLEDKDYTTEILERYARYIDENLDNRCPYCVYNICSEHDNCFDGILENLKEKIKIK"
     gene            88578..88778
                     /locus_tag="ACGI3L_000116"
     CDS             88578..88778
                     /locus_tag="ACGI3L_000116"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195855.1"
                     /translation="MIKERFKAKDSFNMDEFTKIWLMDFKEDFDLSLKKMIENTIKKS
                     IKDTYEETERAITNIENLINKL"
     gene            88983..89267
                     /locus_tag="ACGI3L_000117"
     CDS             88983..89267
                     /locus_tag="ACGI3L_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5052 family protein"
                     /protein_id="HFG9195856.1"
                     /translation="MKKFLLTGLLGTMLIAMSGCTGIQSSMKDAESDVSGLNRTVNVY
                     SDNGEVLKTYTSKSMRVKDGDGGTITLDFDGKRVIICNAHVVIEENSSNK"
     gene            89464..89598
                     /locus_tag="ACGI3L_000118"
     CDS             89464..89598
                     /locus_tag="ACGI3L_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195857.1"
                     /translation="MILNIATIFNLGCMVANYLQDNTNGILLNGFCLIALLLLNNDLD
                     "
     gene            89625..89777
                     /locus_tag="ACGI3L_000119"
     CDS             89625..89777
                     /locus_tag="ACGI3L_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195858.1"
                     /translation="MKITISIEEAMDIIKQHYENKGIEIKDLSFNLEKTGMVRNIKFK
                     GEIILK"
     gene            89988..90410
                     /locus_tag="ACGI3L_000120"
     CDS             89988..90410
                     /locus_tag="ACGI3L_000120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9195859.1"
                     /translation="MSYPTAIQEFSNQEISIDTVDIRDDSRANIKQDYLKFQPKEKYD
                     VIITNPPFNLSLDIINKALNDVREGGFVIMLLRLNYLGGKVRQRLWGNNMPKYIFVHN
                     RRMSFTDDGKTDSIEYAHFVWQKGYNPKFSQLKVLISQ"
     gene            90436..90648
                     /locus_tag="ACGI3L_000121"
     CDS             90436..90648
                     /locus_tag="ACGI3L_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195860.1"
                     /translation="MEINRRRCEYAARTGRYPNSLILWEGYYSLLNIQYIEDKTRGYI
                     TKFNGMDVIKCNDFLKIELFEKNINN"
     gene            90677..93748
                     /locus_tag="ACGI3L_000122"
     CDS             90677..93748
                     /locus_tag="ACGI3L_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFG9195861.1"
                     /translation="MRYNNYHSHKIYSNIRSLDVITKPQQYIDRAIKLGQNTYFTTEH
                     GYQGNVYEAKTLCDEYKLKMIIGAEFYYVNDINEKDRGNYHLIVIAKNNDGYKQINKA
                     LSLANKNGYYYKPRIDEKILFEIFKPGDVVITTACVAGILKLENREELILKLKNYFKN
                     NFFLEVQSHPHKTQALHNKDVLELSNKYNIDIIHANDSHYIYPEESKYRTKFLKAKGI
                     NYPEEDGFILDYPNSEDIFKRYEKQNVLTKQEVERALKNTLIFDECEEITLINDDIKL
                     PSISKNPNKELKEILNKEWLEKRKNIPKNRWNEYLDAIRYEFDIIEKTHMEDYFIIDY
                     KIVQRAKQEYNGLLTKTGRGSAPSFIITNLLGLTEIDRLNAPVPLFPTRFMSVERILS
                     AKSLPDIDLNAEDAEPFIQSTRDLLGEENCAWMISYKPLQDASAFRLWCKANDMKLSE
                     YDEVAKNLDKYTNDVFWKDVIKESKVFVGVVESVSFSPCSMLIYDRPIDEEVGLLKTK
                     DGVCCNIDGYYCDKYKYLKNDYLTVKVWSLIRKICELANISIPTIEELNILLDAKTYD
                     IYKDKLTCTINQVDSDYATNLASKYKISSVAETSAFVASIRPGFASLLDNFINRESYT
                     TNVKELDILLEDSYHYLMYQESIMKYLIWLGIEESESYDIINKIKKKRFKEKELKELH
                     IKLKNNWIKKVGTENNFEDTWQVVNDAASYSFNASHSLSYAYDSLYCAYLKSHYPLEY
                     YTVAFNLYNEDTERTRKLTDEIEYFSIKLENPKFRFSKSEYFFNRDTNSIYKGIESIK
                     FLNSDIGEYLYSLKDNKYDSFLELLIDLQGHINSKQLSILIKLDFFEEFGKSNKLLET
                     YDIYNSIYSKKQFKRDNLPCDINTMRKYSNKETEKIFKEVDTKELCSYLESQIENTDI
                     PTNEKIQAHFEFVGSCNIKDSNSNPRYCLVIDIDTKYSPKVTLYNISSGNIKIFKVSK
                     PIFEDNKIDVYDLVYLKSIKEKAKSKKVDGKWIRSNTETEWWIQEYWKIEN"
     gene            93851..94102
                     /locus_tag="ACGI3L_000123"
     CDS             93851..94102
                     /locus_tag="ACGI3L_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195862.1"
                     /translation="MISILIDEQRYYSLLEEKKDLSMRIDELKEENAFLKQENEEYEE
                     ILNEWECVRKEIVATCKKKEILGEKPSELEMVLQKIEDI"
     gene            94102..94422
                     /locus_tag="ACGI3L_000124"
     CDS             94102..94422
                     /locus_tag="ACGI3L_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195863.1"
                     /translation="MSVNKIYEKKEYIIIKSKSGYIVYNTNKEFKEGHTHLKSYNAAK
                     TAIDLVIKRRLPKSYSIYFLTSLMRISNDVQYIKHISDIVYIRNNKGLKEKYINSKNI
                     KKNY"
     gene            94497..95618
                     /locus_tag="ACGI3L_000125"
     CDS             94497..95618
                     /locus_tag="ACGI3L_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HFG9195864.1"
                     /translation="MKSYKEKQFLVFEFEDGKNVKYNLATGEYVGKSGRIVKDVCTQL
                     RGYNLHEVINSFEDENYKCFLNFVDGRVNRSKSSRAWGRRVERIRNIGSFLNEINNYS
                     EYEQLFSAGLKKIIYPIHCDIKSIPKGLISICRNYSITLSDRLIQGYSKNPNLYNNLL
                     SLELNSIRKTNLISILDSGYDRMIFDRLIDIYKYKPQSLINYIDNLMTYEALNGLEST
                     LNELYDYVVMMSVISDKYEKYPRHFLTTHKIASRNYNRLKTQFEEEVFNKRIDKSLEY
                     SYQDYKFIYPKNTNEIKDEAVQQNNCVSSYIQNVIDGKCHILFMRKKDNLSKSLVTIE
                     VRNGKIVQAKGKYNRDVNEREQEAIDKYNNRIERMKKIC"
     gene            95612..95737
                     /locus_tag="ACGI3L_000126"
     CDS             95612..95737
                     /locus_tag="ACGI3L_000126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195865.1"
                     /translation="MLIEGTKIRLMKEIQGFEILKHQLLAMIQMSLNTIKVLSYV"
     gene            95823..95978
                     /locus_tag="ACGI3L_000127"
     CDS             95823..95978
                     /locus_tag="ACGI3L_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195866.1"
                     /translation="MTCKLKDICENKNTDCDYCCYNPNTYLEDAFEWNGEGKEPSSEE
                     LDDALAE"
     gene            96022..96582
                     /locus_tag="ACGI3L_000128"
     CDS             96022..96582
                     /locus_tag="ACGI3L_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195867.1"
                     /translation="MRWRNILVTSVLVMGSSIHIFANTKEMSTSRMDKNIVADTAKNI
                     NLMYKYEWEQHKNSSEYKLEIKRINLEKGLGIKIEKLIPVTWEVSYYTSLNCENSKYG
                     AITATGEKLQYGFVANNHLKFGTKILVDGNLKVVKDRGSNKYFGNSNAIDVFVPKLEG
                     ESDYKYYKRVNNMGRHYKEGYIIVEG"
     gene            96594..97262
                     /locus_tag="ACGI3L_000129"
     CDS             96594..97262
                     /locus_tag="ACGI3L_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195868.1"
                     /translation="MNVNGIKIPGIIDVSNVYVYGIKESIIASGYPMYEQQVIDMKKI
                     NISEKDLKRANQLGKSKQGSGHDCFSKGIIIQMDLQWSEYMWRQWDRYHHNDYVSSQS
                     KMHRLSKFNLDDMCNKYVDKNTINFLNELIHEYNNFEELKLNNSNNIILRNGEKVEVT
                     KETLWKIIISNCPSGLMLTARVTLNYLQIKSMINQRENHKMEEWRILCDFFKTLPKYK
                     ELMM"
     gene            97308..98201
                     /locus_tag="ACGI3L_000130"
     CDS             97308..98201
                     /locus_tag="ACGI3L_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195869.1"
                     /translation="MAEKRINYNQVFVSGEVLDILNIARMNQGTGQEAIRFTLKVETA
                     PNESVNVDYFTSMFKSDGSPNQMFLGIETIANEIKTRAEDGKGDIVRCVCSLDNNLYY
                     KDGEKKERFQISGTFCNREKYDDKGNPIDDKGEVVKSIKASQVWRVYTLIENIEEKED
                     DLGKYLEIKGLINKYGKQGCNMTFRIHNEDMIEGFKSLYKIGDVGLLEGTVKSMVVSK
                     SAGFGSRIKKSAFTFLEIEGGDEPLKDGDKIFSDKNYPFTDKNIEAMREKIKEKDEKE
                     KQRDIDKNGKTIEISDDDVPF"
     gene            98241..98798
                     /locus_tag="ACGI3L_000131"
     CDS             98241..98798
                     /locus_tag="ACGI3L_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HFG9195870.1"
                     /translation="MEVKEKTMNDGFKKVVNEEIKTYISNLYSDRIDGLKESDSQIEI
                     TKALIAFHLDIESIPKDNTNPFFRSKYANLDTILKAVNPLLAKHDLILMQSAEDAGND
                     KVYIKTKLKHSSGEYIESNSAPFKPAKTNDIQARGALETYLRRYAVQSVLALSFEEDD
                     DGNSLTNKSKGKSEEENSTIKKSRV"
     gene            98859..99410
                     /locus_tag="ACGI3L_000132"
     CDS             98859..99410
                     /locus_tag="ACGI3L_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195871.1"
                     /translation="MNCKCRFCKKKLNTNDAYKVEHITSGGNKQNRYYCNEQEYRKEQ
                     QDIYFWKQCQLGIDYIMGYTVINNQKNKMLQEIIKGGYTREELYDCIIEKKDEVIELL
                     NYRKDIEEEYPKLCYVFTILKGSIRDITIKNKQMKYEKENERIYKEVEKSEEYYEIIA
                     PKKVIYNKRQSLFDKVKGVYQDE"
     gene            99451..100977
                     /locus_tag="ACGI3L_000133"
     CDS             99451..100977
                     /locus_tag="ACGI3L_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaB-like helicase C-terminal domain-containing
                     protein"
                     /protein_id="HFG9195872.1"
                     /translation="MVLGTMLKSLTLFSEYKISESDFIIDKVKFFFSLGRIMSKTHNE
                     LDEISVAKFVSSNKLKSEYERYGGWNSLSSAMEYGKETNIAAYIDDLAKNNLLIALDK
                     RGFNVIKEMEHNGLKFIPFEIFQSMKCREVEEFYEGLISSCSVNSIKNNMKVENLLLT
                     KDDREKLKQKTEAGTPYNIIFEYTEKEIGLSNNEESKYIYSLPILSNRTNGIGKGGGI
                     NIIAGFSGIGKTTLLFFNYILAMIYRGEKIVIFANEQKSQYFKSMLVSFIAYNIFNYH
                     DLDRNKIDNGDFTDFEEDLMEKIEKFLRDRCFAENLKFIYMEEFEISEILRKSKELVT
                     HQGFTGIAVDTFKSEDSSDAHYTGKLIENSKLLDSFGNKYNVITMLSMQLLTAQENKS
                     SYLSAGDLSEAKAVKNVCGLLKLMRKVVNELELDSTNKKFFLKPYKLKYNKLKKTTER
                     EYIQFDAKDLQKEYRLLFLNKSRRGQDGDVILLRFYGKTGRLEEIGRCEKVYRGQLSY
                     "
     gene            100987..102048
                     /locus_tag="ACGI3L_000134"
     CDS             100987..102048
                     /locus_tag="ACGI3L_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHC2 zinc finger domain-containing protein"
                     /protein_id="HFG9195873.1"
                     /translation="MEIKDLTNEQVINFMEYLGSDLSPKSNDRQLIFNTCLCHNGDSY
                     KLFYYTESKTFHCYSSCGHIGSLIDLLIHINKYEFKDAINEIKDFFGISNQPMLRKGF
                     RIKKKVEQIHDIKDIQIELLPTPKKPYVYKTFQQVPIEEWENENISFEVLKTYQVYYN
                     LYENQIVIPHFCWHDRARPVGIRVRNLDEDKAKSFGKYIPLWYDNRCYNHRLSLNLYG
                     LNVNKKSIKNSKKVIVFEGEKSVLQMATMYKNNPSVAICGSNFSREQKKILIDLGIEE
                     LIIAFDRQFKVKDDEEYVIWRDKIYKLVQDIKDVVNISVIWDKYNLLGYKDSPSDKGK
                     TIFEKLLKNRINIENFVKQ"
     gene            102166..102618
                     /locus_tag="ACGI3L_000135"
     CDS             102166..102618
                     /locus_tag="ACGI3L_000135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195874.1"
                     /translation="MKIMSISIDLLLKNMCICILDNGHIRELSNRDIIADKFIFEIYK
                     IFNNHNCDKLVLDTSGIGIAYYQDLEKYIDKNKLIGIYLTEKNNSNKILMNFLNDESF
                     YNLGLEICVKNNGGRIYPDMSKYDEIERGIIECIMLANYYSNPSIESE"
     gene            102944..103750
                     /locus_tag="ACGI3L_000136"
     CDS             102944..103750
                     /locus_tag="ACGI3L_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195875.1"
                     /translation="MNIFNKKYGRNVKITEAEPPSPPPKQPNFDMDNIQYDKEMKRKL
                     LEMEKIKIDSEMKKNSEEWIWIEGYKGTDRDMKCRNFQYELNKTYSVEEIHRGNINIY
                     DYGFHLCLDLKDVFRCYNLNLSNRFFKVKALVRREDKYKYEMEQSFSSIRPGAKCSIG
                     AKEIILFRELTFEELKQDIQDKFPKINNELEWNLIKKLGIYKYYNKIFINKMKEIGYS
                     DIFSQVLFDEYHPLINPHRTMNILDKAIAYSKENLSKDMIIYLLMKEGCR"
     gene            103747..103899
                     /locus_tag="ACGI3L_000137"
     CDS             103747..103899
                     /locus_tag="ACGI3L_000137"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195876.1"
                     /translation="MIVFELLIIIFIAILMVTIFLSCLLVSISMIPKIIDEIKDIIDK
                     IKKEKK"
     gene            103901..104095
                     /locus_tag="ACGI3L_000138"
     CDS             103901..104095
                     /locus_tag="ACGI3L_000138"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195877.1"
                     /translation="MEFKKELEVMEDSEIKFIQSLNRINNNIRINEETKICLEKEIYA
                     SSRVLSMLCDLNEIYSKQNK"
     gene            104131..104658
                     /gene="yyaC"
                     /locus_tag="ACGI3L_000139"
     CDS             104131..104658
                     /gene="yyaC"
                     /locus_tag="ACGI3L_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HFG9195878.1"
                     /translation="MDILKISYNNLNAVSKISDVLRDIVNEDTLIVCIGSDRVLADSL
                     APMIGTIMEKSNIKNKIFGVLGDSIDALNLEQKIQAIKNNYTNSNIIAIDAGISKISD
                     KGTIIISNKPVKPGLGVDKKLLEVGDYSIVGIIGRNKYDIYDTSDPELILDLADVISK
                     SLISILLEKEERMIV"
     gene            104655..104909
                     /locus_tag="ACGI3L_000140"
     CDS             104655..104909
                     /locus_tag="ACGI3L_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195879.1"
                     /translation="MIQEVRQEILLKNGLILYTGDLVEIKYKSDEDVIEHTCKGKIKE
                     AKELFIKLDTSKKYKTSERMIYSWELKEIKKVDDEDEKDN"
     gene            104893..105150
                     /locus_tag="ACGI3L_000141"
     CDS             104893..105150
                     /locus_tag="ACGI3L_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195880.1"
                     /translation="MKKIINSKYRALYLFIFFLIFNLIYSLYFGRNTEIGFYSSTSCI
                     EEYILDIITSIGLFFSMMLAGFDVTENFINSLRDYCEEDAK"
     gene            105140..105370
                     /locus_tag="ACGI3L_000142"
     CDS             105140..105370
                     /locus_tag="ACGI3L_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195881.1"
                     /translation="MQSEVNKLELKDYISKVELNDMPLTLDNKYMLNEISISEDSKIF
                     AVKDTSGITSYYTEIEFNKLFRGINSILENII"
     gene            105445..106284
                     /locus_tag="ACGI3L_000143"
     CDS             105445..106284
                     /locus_tag="ACGI3L_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFG9195882.1"
                     /translation="MEKELYSFSKLNAFNTCPFQYYLTYVKNLNREQSCYGYYGNELH
                     SLLEQLQQRKITNQEAIQKYNEVIEYANLMDYNFPTPNSRINYLECILHYIENFVPIE
                     CDRYYIEEYFEFDINGITMRGYIDLYYIIGNKIYVIDYKSSSKFSKKDLPKKSMQLIL
                     YAMYLKEKYPDKIIEYVAFDMCKYMNNEKGVLIERNKIDSINDYERAIVKIKYTKELE
                     KQLIDFVVDTVTQIKQLDSNDESVWCKSDDKSNQFFCKTLCSHYNKGCKHKENKSFRK
                     SKS"
     gene            106322..106642
                     /locus_tag="ACGI3L_000144"
     CDS             106322..106642
                     /locus_tag="ACGI3L_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195883.1"
                     /translation="MNIPKQVKVGGLFYKIEETEEPILVNNQLCYGLADYGTETIKLS
                     NNLQSERVKEATFLHELFHCIFRDRCIESEDEEYLVDVLSKGLHQVIIDNPNIFELKV
                     SIDG"
     gene            106635..107216
                     /locus_tag="ACGI3L_000145"
     CDS             106635..107216
                     /locus_tag="ACGI3L_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFG9195884.1"
                     /translation="MDKLKNIFVFLGYSGSGKDSIVTEISKQFNIPILISHTTRPPRN
                     YLEIINKTYYFVDNKFFKKEKNNFIEMRKYIVHDGSTWLYGIHKSELENKKYALTIVD
                     ASGYKALEKYFTGTKTKLVPFFINADEDTIRKRLIDRGDNLKEIERRLVDDKIKFKEF
                     LNSENYIVIANNLSITNAVEQVKIHMKEGIQWS"
     gene            107207..107701
                     /locus_tag="ACGI3L_000146"
     CDS             107207..107701
                     /locus_tag="ACGI3L_000146"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFG9195885.1"
                     /translation="MVLALDVSMSSTGWAVINRNKNILKYGKIVTKKDKFKSEDERMC
                     YICNAIQELIITHNIQIVLIEDQFTSRNSKTILSLRKLLGAIMRTVKLNNIEIEYMYP
                     VSIRKYLLNNGKAKKEEVAAYVRENIIDIGEYIDRTCKAKTSDIYDAIALGIAYLNKL
                     DTNR"
     gene            107725..108228
                     /locus_tag="ACGI3L_000147"
     CDS             107725..108228
                     /locus_tag="ACGI3L_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFG9195886.1"
                     /translation="MSINVKIKKLNQNAIVPSYAREGDSGIDLYTLKDTVIPAKSAVA
                     ISTGISLEIPYGYEMQVRPRSGISLKGMFFTRYVTIYDKVQPKKQIRKIFVAHPTVRL
                     GTVDSGYRGEIKIITYNEEDFDILIPKHTKLAQGVFQQVPRAILKVVDELTSSERGSN
                     GFGSTGI"
     gene            108393..108566
                     /locus_tag="ACGI3L_000148"
     CDS             108393..108566
                     /locus_tag="ACGI3L_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195887.1"
                     /translation="MYRYDDYVNLINDLELPKEIRNKCVRVIMTLENMQDIMVVHKFK
                     TYVVNEKYIEKVA"
     gene            108686..109435
                     /locus_tag="ACGI3L_000149"
     CDS             108686..109435
                     /locus_tag="ACGI3L_000149"
                     /inference="COORDINATES: protein motif:HMM:NF019976.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HFG9195888.1"
                     /translation="MFKEIFEKVFMSEEVSKTVKEVNNIIKDTKIQVKGGFGELRLDF
                     ILSRLGKDYIIIKDIIVPGSNKTTQIDSIVISMYGIFVIECKNFSGYIYGNDKDKVWT
                     QIVGKTKNTFYNPVRQNYAHIKAIENIIGNKYNIYSIIVFSDKATLKNVMISGNNIIV
                     INESEILSTISKCKDVTIDKEEIKIIRDKIFDCMKTTNQNTREHVRNLKNITEEDKCP
                     RCQIGHLIKRKGQYGEFWGCSQYPKCKYTRK"
     gene            109724..110836
                     /locus_tag="ACGI3L_000150"
     CDS             109724..110836
                     /locus_tag="ACGI3L_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9195889.1"
                     /translation="MNAFIRKRNKNYVVYLEFRDDESGKRKQKNMGAFDKKRDANKRL
                     AEVKDSIYKDSFLVPNEITLAGFLLDFLEKYKDNISASTYKSYIAICKNHINPSIGKY
                     RLQELRNIHIQNYIDDLAGNLNPQTIKVHINVLRLAIKRAYRIKLIKENIIDGIESPR
                     IKKFKNEIYDKEHMLKLLEVAKGTNLELPISLAIGLGLRLSEVLGLTWDNIDFDENTI
                     TVNKITSRLDGSVILKEPKTESSVRKIFAPIELMNLLKNYRLEQNKKLLRSIVRNEYN
                     LLFFDRKGNPIAEDVMSKKFRKFLENNDLPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNINTTLNVYSHVLKEMDKEASDRISENLFKAN"
     gene            111073..111207
                     /locus_tag="ACGI3L_000151"
     CDS             111073..111207
                     /locus_tag="ACGI3L_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195890.1"
                     /translation="MENLMMSIIAGVIASYIYDKLKCHSERPTKSGWELNIKFHKNKH
                     "
     gene            111413..111790
                     /locus_tag="ACGI3L_000152"
     CDS             111413..111790
                     /locus_tag="ACGI3L_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9195891.1"
                     /translation="MYLRKLSKSELIVMKFIWNLDTKVKSYQIINYMKEKYSWSEKTT
                     LKTLSKLSNKRFIYVQETSQCTYYTISIKEDKYHEFISQKIHKLLGCNSIKSLLASLF
                     QEELTDEKITSLEEWVKNWEEEE"
     gene            complement(111931..113193)
                     /locus_tag="ACGI3L_000153"
     CDS             complement(111931..113193)
                     /locus_tag="ACGI3L_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9195892.1"
                     /translation="MKFKRKALTLAIISSIVMSSTLLVSAKELKFRPPAHRIQGANKY
                     ETAGLIADRRKYTQAIIINTDKSLADGLSASGLAGASNSPILLTKQNSIPNSTLKRLD
                     KFKKIYLIGGVNSISKNVENILKNKKIKVIRIEGKDRIDTSYNVAKEISNLKKVDEVY
                     FTNAYQGEADSISISPVAAKYKNPVVLTNGKNIPFKTDGVKTYAIGGTASINDSLVNS
                     TKATRIGGVDRLDTNEKIIKHFYKDELKHPNQICIVSSDNLIDALLSSTIHKEYPVFL
                     VNETNDKSLVTSANFPIIIGDIKNEILDQCLTPDYMLTGNTKRSDISKALDAIYKAKG
                     SKAHEYCYTYNYGNSRYKKAENIDFPHYEFEIISVKNVKQDESSTDGSDTYTDKEDSI
                     KTVGTLIVNSETLEVYEYSFDTQKLTKI"
     gene            complement(113348..113668)
                     /locus_tag="ACGI3L_000154"
     CDS             complement(113348..113668)
                     /locus_tag="ACGI3L_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9195893.1"
                     /translation="MQKIPQAELKVMKFIWNKNDIVTSKEVMEAMESEYNWKATTTLT
                     LLSRLTIKRFLDSERIKRITHYTILITKEEYKIFETKRFLEEVHSNSIESLISSLEDC
                     YKNK"
     gene            complement(113806..114156)
                     /locus_tag="ACGI3L_000155"
     CDS             complement(113806..114156)
                     /locus_tag="ACGI3L_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9195894.1"
                     /translation="MLEDEIYNVIGKRIRNYRRKAGYNQNTLAKKAGLFPAYIGQIER
                     GESKASLRSIFKIANALEIPLEVLFENIIQNENDVETLSSEAYELIDSLTVKEQKAII
                     RLIKEIIEYRKFEE"
     gene            complement(114437..115375)
                     /locus_tag="ACGI3L_000156"
     CDS             complement(114437..115375)
                     /locus_tag="ACGI3L_000156"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9195895.1"
                     /translation="MATFEKRSKRIKIEGNINKNNEKLIKGFLQAKKIAGLSEKTIYV
                     YKCDLYTWAKYLHDEMEDLLIEDCTEDDIMEYISFRMEDNHVNRIKVIFSGISSLYDH
                     LRRKRIVTENPVSLIERPKKGLPVVEKHFLNIEQAKELQDKLSKRDDLQLEVYINFAL
                     STAGRVTATSNLRWDNIDFDNRVCENIKEKGGKIVDFYFSEKVKDLLLKLKEVRKKED
                     IVNDYVFLVKYDKEYHKATSNVLRSWAKKAGKLIDIDNLAPHSLRRSFATIAKANNLP
                     LEDISTILNHESTDTTKIYIKEDKGKISKSKDMIGL"
     gene            complement(115410..115721)
                     /locus_tag="ACGI3L_000157"
     CDS             complement(115410..115721)
                     /locus_tag="ACGI3L_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195896.1"
                     /translation="MLSKEMVELLSQYGYTAILLMVLMLWLGKYLEKNRQLEQDDRKK
                     ERAYFSREIKEQRTLFGNTIDKFDDKLDKFAEALNTNNSRLERVETDITKIKDKLETR
                     D"
     gene            complement(115722..115973)
                     /locus_tag="ACGI3L_000158"
     CDS             complement(115722..115973)
                     /locus_tag="ACGI3L_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9195897.1"
                     /translation="MDIMQFIPENLIMLIGGLYILGTFIKESNIKNKYIPFILLVIAM
                     ISSCLFMKELSIEAVFEGILCWGASIGINQIQVQNRKEK"
     gene            complement(115985..116602)
                     /locus_tag="ACGI3L_000159"
     CDS             complement(115985..116602)
                     /locus_tag="ACGI3L_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFG9195898.1"
                     /translation="MNILDKSTATLEQVFSYLDTLKNNSNPPHFLCGAIVPIIYKEAE
                     KKGVNPVIAIAQAFVETGYFNFGRVLNPSYCNMCGLKGNKGGGDLDPTAHTRFNCWED
                     GVSAFIDHLALYAGAKGYPKYSELVGKVEYKVNGTTLDPRHFPYLHGEAKTVESLSGK
                     WCPDMNYGKSIINICNKISSMKVENNDVKLEQIKTKVKELNEILG"
     gene            complement(116614..117429)
                     /locus_tag="ACGI3L_000160"
     CDS             complement(116614..117429)
                     /locus_tag="ACGI3L_000160"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9195899.1"
                     /translation="MNIKTLTIHAGHNPDNKIGSGAIGNIKESTEARNVLKELLPLAQ
                     KECKVYDCTCNNGTSQSDILNKIIAKCNSYNTDLNVSIHFNSGGGRGVEVLVYNLNDK
                     ETVEIASRICKKITETYHAKGDKDFKNRGVKEKKTLAFLRRTKAKSILVECCFVDTSD
                     TKKYNAKDMAIDIYEGIFNKSVAGKPQDNKVKYAIVYEGEVDKVIAQLMAMNYKTNEV
                     SVCDLENYVPGHCENLYVIGGASSKIKTSERFTKLQGDDRWATLHKVLDFIGK"
     gene            complement(117508..117678)
                     /locus_tag="ACGI3L_000161"
     CDS             complement(117508..117678)
                     /locus_tag="ACGI3L_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195900.1"
                     /translation="MYNILKRMIEQKNYETREELQTKLDVFYAMNRIKESEYTELTNL
                     LNKEDTLVEPII"
     gene            complement(117704..118030)
                     /locus_tag="ACGI3L_000162"
     CDS             complement(117704..118030)
                     /locus_tag="ACGI3L_000162"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195901.1"
                     /translation="MDIEKKIEILIEYGFENDLNNIDNYFIADGKKIFTPVIKNGELI
                     KTGEQVYNEWLELQNNPPKSEPSIEEINADKITILIENQKQQDSLLVDNAYRIAMLEL
                     NTNNVL"
     gene            complement(118045..119946)
                     /locus_tag="ACGI3L_000163"
     CDS             complement(118045..119946)
                     /locus_tag="ACGI3L_000163"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195902.1"
                     /translation="MIYKDLLKKVNDIENLKEVDNIKCSTDTGEYTIENSKKGYLTNF
                     NVEGKTLIDLWGKTSSDFSLWKATFVDGKINILTENDIRYSNFFTINYTSYKPDTIYT
                     IIVDVDKNTLPSTSGIYIHSLGEENSVFIPNLTNIAIPGGVIGKFKYTFTTISDLNDC
                     NVVLRSVLDNDTLTSGYEISLKITILEGDYTDINIDYSNELLSVGQRDKIEFLSYQYS
                     GINIFNKNADFKDNYILQYLSGEELISEASNHKYTLDYIEIEPDTEYTFYNCSRNICW
                     YDINKSFITASLNERIIGDKDIFYIARSPKNAKYLRVTIIKDLHDNGNKTIITKGNKY
                     DKKTIPYTLRSLPNGIKDEIVYKNDKYYLIKRCEEHTYTDIGNLNLSHVYDNTLQFMG
                     TLTPQAVVDSLDIAYVLCNNLNGKSRNDFNNNDIEGCSTTGSGDIAFKILKSKLTTQD
                     GNGFSEWIKNNPITIIYQLSKPQEIELTSLNLEQYNNQTKFICNTGIVIPDISFESTQ
                     NLGSHIEVIRNNIKNYNVRIDFPFSINFLNGWQPYLGYASSVGNYCTNNNFVTINATI
                     NGGVTTAGTIIGKIPSKYAPRKNIIVIFQTTDGKYYNGIIRTNGEIEIYYNDITYRSW
                     LYLYVNYLI"
     gene            complement(119974..120156)
                     /locus_tag="ACGI3L_000164"
     CDS             complement(119974..120156)
                     /locus_tag="ACGI3L_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195903.1"
                     /translation="MNINNVVVRILAERILSRGLNPLKNRPFELDDVTNEDYRKAVED
                     CIIKESGVVERVETTK"
     gene            complement(120156..120449)
                     /locus_tag="ACGI3L_000165"
     CDS             complement(120156..120449)
                     /locus_tag="ACGI3L_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195904.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGN
                     IDYSKQYIESINPITKEPILKDIPIYLSEEEKRIQELENQILLNENEKVGGLL"
     gene            complement(120463..>121322)
                     /locus_tag="ACGI3L_000166"
     CDS             complement(120463..>121322)
                     /locus_tag="ACGI3L_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195905.1"
                     /translation="LTKIEYFIDDILKETITTDLTTEKTINYTLEDNALHILKIVVTD
                     SNNTTAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALKNIEAS
                     LNNTLVELSEKIKTSFDSSDASVQDLMNQLTQANNTISQLNSKYKYATGTAYARENSS
                     LIACVYDPNTSHTVTETSPYWLDLNGIGFIPDIFFAECEYEPHSNAFYKYFVFAIKNT
                     FPISNNTGFVVNIAFNKEYGDESFKLRGALYTLGKRHVSMDNNGVRVPSLSTLNDFRA
                     YKWHAIKFK"
BASE COUNT        45002 a        15520 c        16469 g        44331 t
ORIGIN      
        1 aaacattata accacacgcc cagatacttc tgtctatctt tataccgaaa gtataaccac
       61 tacctggact tattactata tctacaaaat cataattatc aaaatctttg ttaaattcat
      121 caaagtatat atctgtatct aaatatcttc cacgttgtaa gattttattt tctttcatta
      181 aatcattcct ttcctattta acttcataag aaaatttttc aagttctata ctattagctc
      241 cagcatttgt acttgtgttt gaaatggtct ctataaagtt atcatctaat tcatgtatgt
      301 atttcacttt ataacaagaa aaaggaatgt ctattttatt aaaaataaca ttcccttcac
      361 taccaaatat tcttcttctg tctgtgtcta atcttagacc ttcaattgat aaaatacctt
      421 ttgaatcagt taaattatca taccattgac ccacttcatc cactgcacca gattctaatt
      481 ctaaataaat taatatatct aagactttat cagataaagc atcatacttg gcttttaaac
      541 tgtctaattg ttgacctaaa tttccacctt cttgcaaaat tttaacacta gcatctaatt
      601 catttactgc gtctgatata tttttagata ctgtacttaa ttcactcgaa ccaactttac
      661 tttgtattag atttattttc tctaagttgg tagctatatt acttttattt tcatttatct
      721 tagttagact ctcatcaaat tttgcatcaa ttttaacact agagtaagta ctatctagtg
      781 ttgttatatt atcatttatt gtatttggta taacctcttt atttgtattc ccatttacaa
      841 ccgttactct tacatttata gctagttcat tgaatatctc tattgtatta gaatctacta
      901 tagtataaga attagtcata cttttcttag ttacttcatc taatatagct acaaatatgt
      961 tttctgtaac aagattatgg ttaactgtaa gcttaaaata ttctccatca gcaatccaat
     1021 ctgattcaac ataagattta ctaaaagcta cattagttgc agcagaagtc atttctgcta
     1081 ttttctcgtt aactttctca aagtcatatg ttaatctatc ctttaaagta tcctttacag
     1141 ttccatcaac actttctcta gcttgtatta attcgcctct agcatcaaga ctttctaatt
     1201 cttcaaacct attttcaaat tcagttattt tattactaac agttgttgtc atatcagttt
     1261 tagcagtatt tacttcaact attttgtcat ctacttcttt tatctttgta tctaattttg
     1321 tagtactttc atcaatacaa tcttctacat tagatatagc ttgatttact tcatcaagtt
     1381 tgtaatcaat ttgctcttgg ttatctgtaa gtttatcttc aaatgtctta tcatacaaat
     1441 caaaagtatt attagctcta gtgtctaagt cttgaaactt cttgtctgtc tgaacttgaa
     1501 catcaagcat tttatcatcg actatattat ctatttcttt agacttagca tctatcattt
     1561 catctaattg gagttggcaa tctgtaagtt tatcatcaac ttgaatttgc atattctgaa
     1621 tggattcttc acgatttgcc tcttgatttt gacgtgttaa ctcattaaac tctctttctt
     1681 cttcttgtat gtttcttata tcttcattat aaatcctaat ctgctctgct ttatccctaa
     1741 cttcttcatt tccaagtata gttatttcaa gctgttcaac tcttttagtc aactctttat
     1801 tattttttat aatctcttct gcttgggcta ttattaccaa taatactcca tattcatcag
     1861 ttgaggtgat atcatcatca ttaatcatac cctcttcaac tctataataa agatttgtag
     1921 tattgagtaa agttccatct ttcacaaggg atagttgaaa tgtatttata ccaacagaag
     1981 caagtgcttg tcggctaagt tctatctcta caataccatt ttctgcatct acaacttcac
     2041 attcaccatt aaccttttgt ccatcacttt ttgtaatgct aactaaaact ctatcatatt
     2101 cagataaatc tattatttca tctttatttt tcaatatagc ttcaatataa gctgttttaa
     2161 catcattttc attataaata aaataatcta gcaatctttt gtttattcta taattactaa
     2221 agtcgacctc tatggtatga ttctttattt cataattttt caaagtatca catcctattg
     2281 ttctttattt tgttcttcta gttctttttt caagttctca atttcttctt gttgttgcat
     2341 gttgagtgct ttataaagta ttagttcatt atataaactt tttatctctt caaatgctac
     2401 tgtatatgct ttttgtaaat ttacttccat attaatatcc tcctaaatta ttaattttct
     2461 cgtttaattc attaattatc atctctaatt cttctctttt ttgtatttct tcttgaagtg
     2521 cagttgctac aacagttgta taaccagatg ggctaaacat taatccattt tcttctccat
     2581 agtcatatag aaatgttttt ccaacataac tatctttaaa atcattagct ataaacccta
     2641 tttgactatc tgcaattgtc ctatcttttt ctgctatata atcaaatgtt gctggtttaa
     2701 aatcatctct tataaaatct aaaaatggtg ttggagtgat acttgaacga gttctattct
     2761 taatatcttt tatgtatact atattctctt taaacttttt atcagattca ctcagagtag
     2821 aacgagcata taaatatctc catttataac gctcacaacc taaatcagtt acagaacgct
     2881 ctggataaaa tgaatatcct acacctaaac tatctccatt tgtaaatgta aaagtagctc
     2941 caccacatct tacaaaagta tcatctcttt caacaataaa gtgttcttct ccatcaacat
     3001 aaatctcagc agtatcatat cctacccaaa aataattatt gctatcatat tttaatctta
     3061 ttgctgaggc ttgactagaa ccatctgatt gtcttgcatc tattgcaaat ccagacctgc
     3121 tacttccaaa taatctgatt attggttcat gtccagatgg agtagttaat atatcacatg
     3181 ctatagctcc ttgatttact gttagaccac tcctgcttat ctctacataa tttgatatat
     3241 cattaaatcc aaattcaatt ttatcaggtt taattcctac aattgagcca gagttattcc
     3301 tcgtaaccat catggttata tcatctttag ttaatttaat ttcagcagca tttgttttag
     3361 ttgcaccatc aacttttgct acttctaatt ttatttcttt agctgtagca tttatctgtg
     3421 aaaattcctc tgatatactt ccacccatac ctgttatgta aattttatcg actgtatttt
     3481 taagttcatt tatctttaag ttatattgag catttgcatt tatagctaaa attctgtctg
     3541 aaggtgtaat tatactatct gaaataactg aattaattat agagtttaga ttggtacttg
     3601 ctgcatccaa tgctgttttt gaagtgttta ttgctactaa gtctactcca gtagttctat
     3661 caataagttt ttgtagctct gtatataaac ttgctttgtc tgtatctaat aaattaagtt
     3721 caatatcaat cttttctttt tcttcatctg taacttcatt atcattaaaa taattagaca
     3781 tattagaact aaatgtacct aaatctgcat ttaacttaat tatagcttta tttatgtttt
     3841 ctcttaatgt tatattttct tgtgaaccac caaaattttt agtaacttct tttactaata
     3901 tatttacatt ttcagctctt tggtctataa gagacatatt ttcttttata tgagatgcat
     3961 cttcttgtac ttctaaaact gtttgatgta ttccatctat atctttttca ataactacaa
     4021 acttttcatt atgcttttca tcagtctcat ataatcccca aatctgttct tctgtatttt
     4081 ttcttgaatt accatcaaat gaaatatcaa aaatagaaga atttatagga acttctgtgt
     4141 gttttccatt gtcatttaca actactaaaa attgtgtgtt tccctctggt aatcttacat
     4201 tagaaacttt taatgttcct ggattatcag catcccagta tatatatttt ttatttgtct
     4261 ctgtatctac tacttgataa agtgtattgt tgtaggtaac aattactcca gtaattctaa
     4321 tccatgaatc tgctggtgaa ttatctaata tcaatttaca tcagctcctt ttgtatattt
     4381 ttcttaggaa tatattcatc tggtagatta attcttttct tctgttgctg aataaataaa
     4441 tgtctcttag agtttaatgt tctcgttgcg tgttcagctt tagtcaaata gtcagctata
     4501 gtccttttgt catcttcttt tactttttta ttacttaaag ttaattctaa agtatccaat
     4561 ttcccatttt taaaattttg agtaaaagat gtaaaataga ctaattcttc ttctttagat
     4621 tctttgctat gtaacactat aatatctccc agacttaaat cacccttcca atgttgtcta
     4681 aaattaatat ctattattct atctaagaag tttataacat ccagagtcca ctctttggtt
     4741 ggaatacatt ttaaacttaa ttgtctctta ccttctgcta ttaaatcttc aacttttaaa
     4801 aaagcatcat ttgtataagt gtcataatag agaaactcat ttaactcatc caatagagcc
     4861 tcattaaata ttaaatatcc atcctcatca gtcgaggttt ctctcttaca aagaatattt
     4921 atatctttta tactttcatc taactttgct atctcttctt ctaaatgttt tatttgaaca
     4981 tctaatatga cctttttatc ttctagttca cttatttcta ctgctaactt agctgaattt
     5041 acttcatctt tatgttctgg attatcataa gttttcttta tatccttttt agcctttata
     5101 gtctctatta catgtaacca ttcattactt ttactatcac gttctctctg tttcttaagt
     5161 tttgtatcta ttagttctct ccaaattggt tctcttattt cattcatttc ctggtatttc
     5221 tttatagctc tactaagttc ttcactcatt tctttattgt ctaagaaata agaataattc
     5281 tcaatgtaat catatcctgt aactgtagct cctattatat ccatatcttc actaccttca
     5341 agcttcagtc tagttactat atcatcacta tttgtagttc tttcaagtga ttttatgtag
     5401 ttatcatgag ataaatataa ctgaatgtta tctccaaaac tgtctatatg atacaaatta
     5461 actaaattat tataagtgtc aaaatcagct atacactcaa attgttcttt tagttcatta
     5521 ttgaaataat ctaaccaatt agaattaata ctctcttgcc atcttacttt ttctctctta
     5581 ttaccttcac tatcagtttc ataagcaatt gaatcatcca cataaccaag tttccagcct
     5641 gtctcttgtt ttaaataatc attaagagat ataatagatg cttcttcatc tttggtaaac
     5701 atctgtaatc catagtcctc aatattcaca tcaatttttc ctagtttaac ttctttagat
     5761 ttagctgtta ctacttttaa tttatcgtct gtagtcacaa cattcttaac tacaaaatat
     5821 tctttattat taagacaaat aagacgttct tcttttactt cttcaaaaat gggatttatt
     5881 attttattaa ataaaaatct atctgtaata tattttggaa tggtcagttg tatttcatct
     5941 actccaccaa gctcacgctt tatagaattt aaaaagttga ttgggatttg acctaaaaat
     6001 gatttgttca tcttgtgaat ggttaatgtg taatcagatt ttatctgttt aagattcaca
     6061 ttaaaatgca tattttatca ccttctttac ataaaaataa ctcatctaat gatgagttat
     6121 aaatattttt attcagttgt agttgccatt tcttttactc tttcacttgc aatgtcataa
     6181 actaaactat cttctctgac tgatattact attattctca taatattgtt ttccattact
     6241 aaattataaa ctactcttat tccaatacct cttaacttta tcttaaaaca atttgtgaga
     6301 ttattattcc ctttattacc taatggttta ccatatccat caggactcgg tagagggtta
     6361 taagaaactt tttcaattgc ctttaaaact tgtttttttt gagaattatc taattttttt
     6421 aaatctttat gtgaatcttt tgtataaaaa atattccatt tcattattca aaatccacct
     6481 caatattttc aaggtctttt tcactaatat ccaaatcttt cataagctca ctttgagata
     6541 ttaattcttc ttcatttata tttttcattc ttttttctgt ttcaagaaga agtttgtagt
     6601 cttctatggc atttatcatt tcttcgtact tttcaggtgt aatcaaaaca catgttggaa
     6661 tattattttt cacaacaatt ttacttccag atttttttac ttcatcaaat attttatttg
     6721 cttccccttt gttgaatcga gaaataggaa ctatagtatt caacatatta gccatcagta
     6781 aatctctatt gttcaacata ataacacctc ctaatagtat atataaatta taacataacc
     6841 attaatattt atcaattaat taatatataa atacatcaat aaatttaact ataataattt
     6901 attttagtat aaaaagagcc acttgtttaa ggtggcaata gataagtagt aattcttgtg
     6961 taaaattttt aaattttctg ttatctgtat tatatcttta ttctactcct gtcgtcaata
     7021 taatattaaa tttaacatta tggaaaaata tggtataata tttttagaga ctacagttta
     7081 gactattagg gtgatggctc tttagttaaa atccccagta agaaaggggg gggaagacta
     7141 tggagtactt agttttgttt ttaataatga taattatgat tacaagaata atcattcatt
     7201 tgacaaagct aatagatgca atcttaaact tgaaagcatc tattaggaaa ctaaagaatc
     7261 accagactgg cgggtctagt gattctgaaa gtaatacata aatctattct ttttattgtt
     7321 aactttaaga actacaccct acagcaaata gtttgtagtc tctttttttt atgtctttat
     7381 gatataaatt tatatcattt atattactat tatatcataa atacgttttt tataaacaat
     7441 attttttatt agataaatat atattttcaa aaaaaatctg actataaatt ataaacgtaa
     7501 gtaaatgagt gaataataaa taaagaccaa ttacatatat taagacctag tattagaaat
     7561 aatttttttg ttattttctt caatcatttt cctcatcttc ttttcaaatt caggcattac
     7621 atctttagtt acattccctt gtacaacaac aaatggtgaa ttataattaa ctgctgatat
     7681 tggagatgca cttcttgaac gagaatttga aggtggtgtg taattaggca tagcaaattt
     7741 acttaaatct aattcatcta atatgtcatt aatatcttct aatgtctctt taccttcttt
     7801 taacttatca agccattctt gtttagtgac ggaacccatt gctaacatgc catcttcata
     7861 tttattaata tattcaataa tagcatcttg aagtttctta acttctccat caagacctac
     7921 aaatttacca cttgaaattg cttcattaat taaatcaact aaattttcat ctgagtattt
     7981 tttctctaac tcttctttta acttatctgc ttcttcttgt agtctgtcag attccttgtc
     8041 atacatatcg ttaacttggt cgtctacatg gtcttgtact aaatcctgta atttcttctg
     8101 ttcttctttt aattgttttt gtaaatcttt aagtttcttc tgaccactta aagaactatc
     8161 tctttcagct attgctattt gtttttctaa atcacttatt acatcttgtt gttcttcata
     8221 atcatcttta tatttggctt cttttcttga atcattgtaa gcatcttgtt gctttttaag
     8281 agaatcaatt ttagctttag tttctttatc tatttcttta agtctctctt caagctcttt
     8341 tttatacatg tctctaattt tttcttgtag gctttgagct tctttaagct ggtctttata
     8401 agcatcttga atttctttat ttaatgcttc aatttcttcc ttagattcag caatttcctt
     8461 attggcatca ggtattttat ttatcaataa atccaaatat ccctctgctg cctcttccat
     8521 tctcttaaat tcttcatcag tcatgttctt tttaagttga tttttatgtt gaatgaagtt
     8581 agttatatcg ccattatctc taaatgtaaa tccatagcct tgtagctttt gttgtagctc
     8641 tttttgtgtt tcttgaagat atgctgttgt ttcagatagt tctttagcct tcttggccat
     8701 taactctttt ttcttttcta acaactctat ctgctcatca cctgtagcat ttttaagtaa
     8761 tacatctatc attgctattt cattatttac ttgctctaca tctttgtaca tagaagtcca
     8821 tgtggaattc ttattaagtt tccacatttc ttcttgtgct ttccttaact cctcattgtg
     8881 ttctttaatt ttattattgt attcttccca ttcttgctca catttaggca gttctgtaaa
     8941 tgtaacttta atatattctt caaggacttt cttagtttct tccaactctt tttttctgga
     9001 ttcatctttt ttattttctt tgtcaccaga ctttgaattt aatttgtcta attctttttc
     9061 tattgatatt aacttttctt catagttagt tagatttcca gtatcatcaa acttaaagcc
     9121 cattttcttt tcttttaatc tatttttaag tctgttactt tcagctttat atccatcttg
     9181 ttgttgtttt attaaatctt tttgttgagc aaataattta ttttgctcct gtaagtattt
     9241 aatcttctca tcacctgtag catgttccat ttttttgtct aatagagcta tttcatttgt
     9301 tactgctgat atagcatttt ctaactcttt aaataattct atactatatt ttacagatga
     9361 gtctattgtg tcattgttta ttgtaacttt aggtttgatt actttgaaag cggatgtggc
     9421 tcttgatact gctcttgaga ataaggatgg ttttggtgtt acaggagttt cgtcacttat
     9481 tggtgctggt tctgatgttc taggttgagc taatagatta gctggaattg gagttacatt
     9541 agtaacagag gtacgttcag ttttattggt cttatctgaa ctatttcctc ctcctccacc
     9601 accagaacta ttagtcactt tattagttac aaatgtagta gtgaatgttt ttcctgcata
     9661 atttgattta aatgactcta ttttcctaat aagccctgat atgttctttg cagcagttgc
     9721 agttaatgca ctaaatgtag tctttatagt ttttccacca tatcggctaa cataactttg
     9781 tactttggct aacaaacctg atacattttt tgctgcttgt gcagtttcag ttctaaatac
     9841 aagtgtagat actttcaaag ctaagaattg ttttactcta gctataagtc ctgaaatatt
     9901 cttagcccct tgttcagttg aagtactaac atttatatga taattacctt gcccaatttc
     9961 ttgtgctttt tgtgataatt gatttaattg tttggatgct tgttctgcac ctgtagcttc
    10021 aatagtagga gtggcttttt cattattaag ttcatctaac ttttgttttg tattgtcaat
    10081 ttcatcttta ccagagttgt ttatggataa ctcaataacc ttagttggat ttgtattttc
    10141 tataaaattg gttgcttgtt caacttcagt ttctccttct gtctttattt gtacagttga
    10201 agttactgtt ttattatcta actcatccat tttttgttta gtactgttaa gcccttcttc
    10261 attagtaact tgaggactta caattggaat ataagattca tttccatatt catctaatat
    10321 tctcatgcac tgaacaactt tttcactatt attaacttga ggatttaaat taggagtgta
    10381 tgttttatta ccattcttat ccaatgtttc tatgcattca actacttgtg attctccatt
    10441 tacttctgca tttactaaaa ggtcagcctt agttccatct gcattttgaa ctgtattaac
    10501 agttttctct gcattttctc ctccttcaac ttctattcca agttgttttt ttatttctgg
    10561 aggtaaattg tttataaatt cttgtacatt tttagctttt tcaagttggt ctaaattatt
    10621 tactataaaa tcaataacag cttccttttt atcatttgga acgttattaa gaatttcatc
    10681 tatctcattt agcttatctg gatttttatt aattatttca aatatagttt cttttttatt
    10741 tggagcttta tctattaagt tttgtaatgt gtctaattta tctataccta ttacttctgt
    10801 ttctatcttt tttttgagat tatcaggtaa aatatcatag actttttttg cttcagtcaa
    10861 tcctttttta tctacatcta tatcatattt taaactcatt ggagcagata ttttttttct
    10921 agcttcctct aaagaattta catctttaaa agcatctgca caatctgtag taaaagacaa
    10981 ctttgtatct tcatttttaa atctatccaa ctgttctttt aatacactca agtctttttt
    11041 tgcgaaatct agtcctttat tattaatttc agtcacaatt ttatctgatt taaaagtatc
    11101 ttgtttgaat ttttctaact cttttaattc ctttttagct ttttctccat ttacactagg
    11161 tgtgatttca ggagcattgt ctcctgtaaa agcatttgca aattgctcat ttaatgcttg
    11221 aaccatattt cctggcaatg caggtaactt atcactgatt tttagtccat ttttaagaat
    11281 gtcatctgtt aattgtaatt tacccttaaa taagtcattt aattgtttaa caacatcatc
    11341 agataattga ccttcgtttt gcaacgtagt tgttacttgt agggctaatt gagcctgagc
    11401 ttctatttgt gaatcttctc caaatgtgaa tccatttatt atatctttta gttgttgtgg
    11461 taaatcttga ccagcttctc cactttgtat atcttcaagc agttttacat tgattttacc
    11521 attgacttct aaattttgag aaaaatcatt taatgcatca aattgatttt taagctttat
    11581 tgcaagactg tctttgtttt caagttcagc taaagatgaa ccataacttt tcaagaaagt
    11641 atgtaatttc atactggcta agtctaatcc agaaaaacct tgttgtaatc caataagcca
    11701 agtatcagca cttatacttc caccacttag cttttgaagt tcatttgcta aaccttgtag
    11761 ttccttagta tattggttca tatcgccaga tgcttgataa tttatgttag catcagttat
    11821 cttcttattc cactggtcta atttttcaac aggaattgac tcacttattt tatcaaaagc
    11881 acttataatg ctattctgtt gtcctacact atagtcatgc caattcatat tagctacaag
    11941 ctcattcatt ttacttttct tttgttcaga ttgtttagca tatgttttag atatatcaga
    12001 attagttaat ctattaatcg cccttttctg cattacctct tcttcttcat tatatttttc
    12061 atattcagta agaagttttt gatgatgttc tgcaaaatct gtttcttgtt gattgtaagc
    12121 cttttttaat gcttctgttt gttctttaaa attagattta cttaaagcat ttttaaataa
    12181 attatgctca tcttcaagaa ctttatcaag ttttttcttt tctttatcaa ggtctttttt
    12241 tgtatctggt gcagtctttg atgtagttat tgcaagttca tcttcttgag actttaaaag
    12301 tttatttttt tcttctatag cctttcttaa tttattaatg acctcatcta agttaccact
    12361 catatttaga atagggtcat tattctcatc tacacccaat actaattctg gtgctatatc
    12421 tgcaatttgt tgtttaagtt cgctaaatct ttcagtttca tcagcagtct tttcggtctt
    12481 actagctaaa ttattgtact cttctgatat accttctaaa ctctttttct tttgttgcaa
    12541 ggagcttatc tcgcttgtag tagttccaat aacttctttt tgtttttctg ctaatttttc
    12601 atacttgtga atagtatcat ctatccattg tattccttta gatatagcaa aagtagccaa
    12661 acctatcata gccccgttca acaaacttgt tgctatattt aatgttccaa taccaataga
    12721 agtcctagat aaactttttc ttaatgctcc caaacctgtt cctgctctag taattacatt
    12781 tgctccatta gcaccagcta catttgccgc cattactgca tgtctaaatg attgtagtat
    12841 tgtagttgta gctttaatag gagttcctat catatttaaa ggatttataa gtctagccac
    12901 atttctagta ccatttgtca ttcccatacc agagaataac gtttttaaag tcataaaact
    12961 tcctattaat gctggtgttg ttaattttaa tctttctaat gtttttataa cactatttat
    13021 tccattagat acagatatta aaccatctaa aaatccatat gttgtatttg aattaaatac
    13081 attttggaat atatctgccc atattgtttt caactcattt aaacgccctg caagactatc
    13141 taaatattgt ttgttttcag cctcagccga accaaattga agcccctgac tgaattcttc
    13201 ccttatttct ttaaaagtct cataattacc cattaaggat tggaatatag ctgcttgttg
    13261 cttacctgct attgcttcag ctaatccttt ttgttcatcc tctctgagtt ctccccattt
    13321 gcctttcaac tcatctaaga gctgaaccat attcttcaat tcgccagtat ctttattttt
    13381 ataaattgtg attccagcta tttcctttaa gccttttgca gttttattta aagaaagtgt
    13441 accatcatca gctgaaactt tcatacctgc taaatttatt gcgacacttt ttaaaccatt
    13501 acctactttt tctggatttt gtatcgcttc atttgttgct gttatcatac ccactgtgtc
    13561 acctaaactg acgccatact catgaagtac actacctcca cgtttcatcg cttcggcaac
    13621 acctgctgtt ccaattgcat aattattccc tgcatagttt caaattgtta ccctacaagc
    13681 tttttatctt gtagttctta catttcttat tcatgtaagt tcagcatata ttttcatctt
    13741 caagattact tgttcagatg gaggacactc gtgggaaaat tatattctat gctattttaa
    13801 acataaaaat agcataggtt catttcctat gcgttacggt gattaaagtc ttttaattct
    13861 ttaatttacc tcggtggtaa catctcagtc ttcaccgatt ttgccccctc ataatattag
    13921 atatttctat ctaacacgcc aaacaattta gcatatccat tgcagcagtt aattctgttg
    13981 ttttctttgt agtatttcca acctgcactt gcatttcttt taaaggttca attctaaatc
    14041 catttattat tgtgtttact gctgaagaag caccttcaac atccatgtcc cctacattgg
    14101 caagtatcat tgattgtctt gcagcagcaa tactttcttg catacctcca attcctgctt
    14161 gtaaagaaga tgctattgat tcttgaactt gtgatgcact cattcctaca tctttagctg
    14221 tttgtattgc tttttccctt atcttatcta actcagatgt gctatcaata tctgttggtt
    14281 ctgcaacctt tttaaggtca gtcatagagc tatcaagctc taatataaca tctttcatag
    14341 acctaattcc gtcagttaaa gcatctccta acatatctcc aatcgaatat gatgctatag
    14401 atgaataaaa atcattaaaa aatcctccac cctttgaaac tgtattattt aatctttcag
    14461 cttcttgtct cgcgtctctc atttctcttg ttagtctatc aaatatattg ttaaaatcac
    14521 catttagatt tcctgccgaa ccttgaagtt gctctaaaga acgtctaaaa gcttcaactc
    14581 tctcattccc aaatgcctgt ctaatagaat cttctattct gctgaaatta gaccttaagc
    14641 tatcaactct ttctaaattt ctaacttctt gatttatctc ttgtattcta ttaactatat
    14701 tacctacatc aagatttaaa tctatatttc tactagctat ctgttttaat tcttgtaact
    14761 cattcctaag tctatttact ttatctgtat ctatattatc gcctaatcca ttaagcctag
    14821 cagatgcttg tgttgccata tcttctattc ttgaaagact tctattcata tcagctaaat
    14881 ctcttgttgc tcttgaagca tcaaacatat ccattctagc ttgagatgat gaattcattt
    14941 gtgcatacac tgaatccaat tgtcttttta atctttcaat ttgctctgtt gttctttcaa
    15001 ttgaactatc ccctaaacct gtcctcatct gattttgaag cctagacaca acatttgaaa
    15061 tttctttata ttgtcttatt aaatcttgtt gttcattatt tatatttcct gtatttccag
    15121 agccaccacc aagtaaacta tcttgacttc ttctacttag tttatttatt tctttcatag
    15181 tagattcaat ttgctttaaa ttacttaaag cagtactatc aatcttgaaa gctttattaa
    15241 atatgccttt tagttgttct gcttgctgtg ataacttatc taattcacct attttcaaat
    15301 ttaatttaat aggcttatct tgaccactat tttttaactt ttctaatttt tctctagctt
    15361 ctttgtcatc aagttcaata ctggttttaa ttttaaactc ttcaaccatc tactcaactc
    15421 ctttttttgt ataaaaaaag acagtcaatt gactgcctta atgtttttat ttaattccaa
    15481 taagtttcca tttcttttat gtcattataa tatttttctg cactttctat ataagaaggc
    15541 atcattgtac tatcattatc taaattctgt tttgtcgatt ttaaatcatg tgagaatgaa
    15601 gattctatag tcctataaca cctaatttct tcttcaaatt tagaaagaag tatattcata
    15661 ttcccactca aagtaatttc attacttcta atatatgaat tcatagcata taattctgaa
    15721 ccccaatatt ttataatttt ttttaattta gtctgattct ttaataattc atgagagtta
    15781 ttatcatcaa tattcatttt tatgttatca aagttttttt tcaactgttc atttcctgtt
    15841 aatactgtat tttgaaaatc tatctgaaat tttcttaagt cataattact tttaaaccaa
    15901 ctatttattg gcctgttttc cgagtccata aatttactat ctaatttttt atcaatgata
    15961 aaaaattttc tctccttcca aataatcttc tcattttcct tttcttcaag ttcttttaac
    16021 aaactttcag gtgtttcaaa tggagttata tctaccatat aagaattaat atctgatttg
    16081 aattcatcca ttctatcttc aaatttcttt tttgtgtcat ttaaatcatt ctttttgtat
    16141 tctttagata aagcaatcaa ttcattcata tctttagatg ttttatctgt aatttctaat
    16201 gcctcttttg ttttttcatc attgtcatct attatgcaat tctctttatt aaaatcattt
    16261 tcctcttcat tagaaaattt atctatagaa taatctgtca ttttatcata gtttttcata
    16321 atatgagtaa gcccttctaa tgatacctct tttttttctt tttttactac ttcattttta
    16381 ttactatcac tacatcctac aactccaaat cctaatatac tcacaatccc aatcaataat
    16441 atcttcttaa acataacatc ccccttatat tctgatacat taattatatc aagaatatac
    16501 gattaggaaa attattacaa ttcgacatta ttttcttttg ctgacgcttg taatgatgct
    16561 aattgttgtc tagctttttt atcatcaagt tctatactgg tcttaatctt aaattcttct
    16621 gccatttaac caactccttt ttaaagcata aaaaaagaca gttagtatac tgtcttaata
    16681 tttttattta attttctcta ataatacttt tttcttttca ttaaattctt cttctgttaa
    16741 tatctcttgg tctttcaaac tgtgtaattc ttttaatgaa tttgaaattt ttgatatatc
    16801 atcatcatct ttttttatat cattattgct ttctatttta gcatttttaa atttagctgc
    16861 ttcattctct acaactaatt taaatctttc catttctttt attttttctt gaatatctgc
    16921 attatttata tttttatgtt ctggaatata aaatacttca taagtattaa gttcaaatat
    16981 caaagttaaa tatatttttt ctacaaaagt atatttatca tatgtaggaa ctatagatat
    17041 tattctcatt tgattttttt cactaacttg catgttaaac ttaatgctta ctaaatcttc
    17101 tatatttttt ttaactgctg tcttaaatcc agcatgaatg atagatattt ttccattatt
    17161 acttaatatc acactgtcac tgtttgaatt accaaaagct tgacatttag ccattgaaat
    17221 atttttttgt atagcctttt ccacctttgt tttttctcta tttctttctg ctattctctc
    17281 taatctagct tctttttctc tagcattatc tattgcattt tttataaaac aataaacaat
    17341 aaaagaacct acaactactc ctataaagat taaacgtcct gaatattctt ccataatatc
    17401 tccccctatc ctgatacatt aattatatca agtctaaagg aaaatttata ctacaaaaag
    17461 gaaatagaag ccaaaacttc tatttccata acatcatttc aaatatttat taatatcttc
    17521 tttactagct tcttctatgt aatctatcat acagattgga atgtctctac tcctagaaat
    17581 atctccgatt tcttctactc ttattttctc atttcttaca ctctttaata ttccaataaa
    17641 tccatagtac tcatggtcat atatagcata tgttttgcct atctcaacca ttacaccttt
    17701 tatgtaatca ttatttatca taaatctctt aagtacctga ctattctctt tcaatatttt
    17761 attaagaaaa tatatttgtc cttttccagt tacaatagga gtgtatctaa ctatagtatt
    17821 cccatcttta tctacaccag tactctcaga aacttctaat acttttaaat ccattgactt
    17881 ttgagttgga gtattatggt cagctctttt cttcctaatt agatattcat tatttctcat
    17941 ccactcaaat aatctatttt gccctatatc tactccattt tgatttaata tcttagatag
    18001 ttgagcaatt agtattgagc ttgatgaact ttctatagcg ttagctagtt caagtttagg
    18061 tttatttttc tcttgctcta ctcttaattt ttctttagta gctctctctt ttttaagttc
    18121 tgtaagtaat tttatagtcc aatctgggtc attgattgcc ttctctaatg cttcattagt
    18181 catataagct ccatgttctc ttattgatgg aagaacttca tcaaataccc aacgctcaaa
    18241 tttttcagca cttgctaatt cgctatttgt aattaaccta tacacatcac cttctggtat
    18301 tatattcact tccaaagttt tagttttact ttgtgggtga ggtactccct gttttagggt
    18361 atacctacaa tgcctttcaa ttgcattatt tggctttgca tatccaagag cttttgctat
    18421 atctgttgca acaaaataca ttttaccatc aatctcaact gttcttattt ctccaaacaa
    18481 ttcattgtta aagcttatta ttctttttac attttcttta ttaattatgt ccataattaa
    18541 tacctcctta tagtttttta taaggaaata gtatataata atattaggtt gaatcataat
    18601 tatataccta aggggctatt caaacttgat aggggagaat agcccctttt cctatcctta
    18661 tttattttta taacgtttag tattttataa tacttattgt tatatttata ttatattgcc
    18721 aacattttgt tatgtcaagt atatatttta taactttttg tgttataata tatgtatagg
    18781 aggtcttaga acatgattgg agaaaaatta aaacaactta gaattaaaaa taacttaaag
    18841 caatccgatt tggcaagaat attagatgta acacaaggag ctgtaggtat gtatgaaaat
    18901 gataaaagaa ctccatctcc agaattgata gttaaactag ctgaatactt taatgtcact
    18961 acagattatc ttttaggtca tacaaaaacc aactattcag tcagtgcaaa tatacctggt
    19021 atgccatcaa tcgtatgtga agataattcc atctatgata tacttgatgg gaaaaaagac
    19081 attaaatctt taaaagatat gaataaattc ttagaaaata ctgattacaa taatgaagtc
    19141 aaagaagttc ttaaaaaata tatgcaacta gatgaaatgg atagaaaagc tatagagaga
    19201 atgatagata atgcatatga acgactaaaa gaggataatt aatatacacc tctttttttt
    19261 ataccatatt agcccaatgt tggaatttta acatgcgtcc acagtggatg ccatttatta
    19321 tatttctatt ctcctttagt gaagaattat tatatcaaca ggagttatta atttggtata
    19381 tcctcaatcc tatcacactc aaagtagtga ccactcaaac atcaaaataa gctcttatgg
    19441 tggctaaaca ccaaacaaaa tgttcctctc aggaacactt gttgaaattc caatactttc
    19501 aaccataaaa atcaacctct tatgttcgat tctaagcaat taaggtataa acacaagcag
    19561 tcatttttac aaaaccttag agagtcctac acgaagttat aatgtttaaa agtctttcat
    19621 ttctttccat ttccttttga cttggcttgg taaatacttg ttctataaat agttcagcgt
    19681 ctttacctga tagttcagga gttgcttgta ttggcttaaa tttgcaccta cccatatcat
    19741 cacctccata atttttaaca aataaaaata accccttata ttcaaaatag taagggatta
    19801 ttttttataa ctttaaaaaa atatatgtac tactttataa gataatgtta attatttctt
    19861 ttaatctatc ctaaaaaatc attttcacaa aatatataaa catattaata ttttcttagt
    19921 acagacttta taataattct tatattatca tttgtatctt taaactcagt attattaact
    19981 aatgtttgta gctccatttc ctctagtatc ttaccaaaac attcatcagc aaaagaattt
    20041 gagataattg atacaccatt aaaatcgaaa attacttttt ctcctttttt gatgctattt
    20101 attatgtcag ttcttatttt ttttcctaat tgtcttgttc ctagagattt tccaaattcc
    20161 aaaaacttta taatcataat tttatcactc cttataaata tccatttaaa atatcatctg
    20221 attcattaac agagattgga atgttttctt ttccatcaaa tatatcatta atatctacac
    20281 ttttgtttgt atttatatta aagtaaacaa ttaatccttg ccaaaatcca gaagaataag
    20341 ttttaatttt tccattatta atgcttaatg tactattgcc tgaatgcata gacattattc
    20401 ctttattgtg tttcataaaa tttgaagtat gatataaacc atatcccctc ttttgaaatc
    20461 ttgaattctt ttcttttatt gaacatttta aagcatcact ctcatttata tttttatatt
    20521 cttcttttcc tgaatttttt aacgtattat atatacccag tccgctatct actattgcaa
    20581 tttttagtat atttttctgt ggataatttt gaactacaat gtaaccacca attggagatt
    20641 ctgaatgctc atttatatta tcaacaactt caaacaagca ataattaaga caatcaaaaa
    20701 cagtatcatg taattcaata ttacatttga ttacattcat tatattatta actatataat
    20761 ttgtatttgt attgtctatt cttgttatct caatgaattt tccatttcca ttatgcctat
    20821 taaaattttc tatataatca tatccaattt cattgtaaaa attaattctt gaaacataat
    20881 cattttcgtt caatattttc tttaccactt ttattccttt atattctaaa aatttaatcc
    20941 aagaaaccag tatacatagg tattcaggaa atatcatgcc attacagtct atgtttaaat
    21001 ataaagtatc attacttgat aattccttat atttatctaa tacatttaat aatcctctta
    21061 tgttacctat tttacttaaa tttatacact caatattctg agaattcata taaaacacct
    21121 catttgttat agtattatta ttattataac aaataagtta atcaaaaacg tttttattaa
    21181 ttaaatttat ttaatattct atccttttac ttttaattct atacaaccta taaaatattt
    21241 ttacatttct atgaatataa tttgatattt tatcaaaatc taaaaatcca cttacgtttt
    21301 caaattttaa attcagttac atgtagaaat ctcttcaata aaaaaacaat ctaaattaat
    21361 tgtctttaat atttattaat acatcttgat atttatatta taataagaat tacaaaaaac
    21421 gattaatgaa taatgtattg caatagaata aaccttctat tatcctaaaa taatagaagg
    21481 tttattctat cttcacacct tagagatgta ctatagcctc tcgctaataa actagaaact
    21541 agttatgtct taaatcaaac acattataaa atgtgtatta tggccactcg ccttatctat
    21601 attaatataa taataaacat cttataaatt ttacaattta atctctaaaa cctatattat
    21661 aacttataca ttcatcatct acaaaataaa ttatatcatt gaacataaag aagctataat
    21721 catttttctt tgcctggtta gccattttta ttatgtctcc agtccaaata tcatcatcat
    21781 aattatatat taaatatttt ggaatattga ctttattatt tgtaaaacta tcttttttta
    21841 attcttactt ttctattatc ttaccacaag attccctaaa atgtatatta ggataatcta
    21901 attttcttgt aacctctaat acttcctcga tatattcaaa tttaaatgtt aattaaaaca
    21961 attatacctc tctccttata tcaatatgtt atatacaagt atatttcaca atatacttgt
    22021 atatgttttt gtatcaatca atgtattaga acattgagaa acaattctaa accgcttatc
    22081 taagcaaatc aactaaacta cctatctagg ctaaattgct cactatatgt tagagcatca
    22141 ccgcttttta attttccact tatgatatac atctactagt ggataacata caacccttag
    22201 aaaactctat aacttaatag acactcgata ttatctattt tactggtacg cctaattcat
    22261 tcattttaga cttaaaacac ttaggtactc tctcttgtgc tttagaatta ctctcttcca
    22321 ttatatttgt ttgaggtcta tatccgccaa caccccagac tttccccttt tctaatcttt
    22381 ccattggaaa tgctgaattg cgtgtaaatg catccaccca atttccatta ttttgtatct
    22441 ctgaagtgac agaattagaa gagagttctg taacatctat agcatctaat aattgtcctg
    22501 ttctacctcc ccaaacatta ggattccatt ctccaactgg agtataacca gaataaacct
    22561 gtttatttac ttcttccttc ataatttctt tcatttcttt tccaacttct ggcatagatg
    22621 cagcaatctt attttttgta taggcaacta gttcatctaa tgatttaaat tccatctaat
    22681 tcactacctt atctttaata ttattcatct tttcaatttc ttcagtttct tttaaaactc
    22741 tatcctgtaa tatctcattc ttcatctgac ctagcttaat ttcagtattc attaataaag
    22801 atgcagttaa ttcattttct atttgaccta tgtaatacat tacattttct aattcactag
    22861 atatattgcc atttattaaa tcttctattt caatatttaa ctctatatta gtcaatttat
    22921 caatcaacat ttcaagaata tcttcttgag acaatgctaa atcaggactc tccataccaa
    22981 cccatatttt atttaatatc tcttctttag tctccttatc aggatttcta acttctatat
    23041 attcctcttt accactttca tctacaattg gtattatagc cctaacttca tcttgtatta
    23101 atttatctac ttgtatttta ttcatatcta tctctccctt attttattat tggatattta
    23161 cacttaatag aaactttaca gtttccagta aacttcaata tatttacacc tcttcttaac
    23221 ctaatccact ttctattaac aatattaaac ctattctcac cagaactatt taaaacagta
    23281 tagtataaat tatctattgt tattttttca tttaattcta atccacttat aactaaattg
    23341 tcttcttcat tatcgctgat agtagaattt ctaatagtta tatctccttc ttttagacat
    23401 tcaatatcaa ttactggagc atattcttca tctacattag acacattatt tagtttaatt
    23461 tcccttgtat ccttgacggt tataactttt tgaaagctcc tataagcata atttgtatat
    23521 ggttgaaact ctatttctaa cacacctttt ttatcttttg tatatctttt tattatcttt
    23581 ctcgctttga gatagtatat ttcttctata ttgtcataac tgataaaagg tttaaattct
    23641 ctctgccaaa accaattaca tatgttttct agcgtatagt catcccactc ataagcctcc
    23701 ccatgttcgc tacacaaaca gaattgtagt gttataggtt caatagtagt ttcatcctct
    23761 gagtaacaag gatttttatt aaaagtacta tcagatttaa tcgcttcttc gtagggcaat
    23821 ccatattcat ttagtatttc atcatcacct aaagtaacta atttaatgtt catggattca
    23881 cttgaaatat tatcaaataa aaacttatca tctaaaaata ccactttatc accttctttc
    23941 atttttttaa gttcaaatcc gattaaaacc agatttaaac gtaaaaaaat aacccctact
    24001 cttttgagta gggcatttta ctatttctta ggtttagtat ctttttcatc ttctaattca
    24061 acacctagca ttgaagccat tctagcagga ttaagatttt catctcctat aaatgtgaat
    24121 gtagcatact ctttattttc atctggtaaa acatctaatg tcatattaaa tccagatgga
    24181 ttctcagcag taagatttaa ctctatactt ctttgtgctt ttgcatttgg aacactcatg
    24241 tataaaacca tatattcacc atccacagtt ttaaccatta cctcagcttc tacaacgtaa
    24301 tttggtgcag tagattcttc ttttattttt acaacttttg cttttggtat ttcttctaaa
    24361 tagaatactg ctactttatc tcccgcatta aaatcggctg tagatattgt tatttctgta
    24421 ttagctcctg taactgatga agtgaattgt aattttttaa ttatagatat tccatcactt
    24481 tctatactat atacagatat gctatttgca actggcttta tattttctaa agtaactttc
    24541 ttagtactat cagatgttaa tacttttctt ttcccaacct ttgcagtttt ctcatctata
    24601 tcagaagata ataacatcgc taattgtgcc atttgtatta cttcttgttc cattgttaaa
    24661 cttgctgtta ttgctccatc aaaagctatt gtatttgcac ctttagcttt tgcataaact
    24721 gattctgaat ccatcttaaa attaaaagca tttaaatcct gtgaataaaa caatacttct
    24781 cctgttactt tattttttac tattacatta cctgcatctt tcactgcaaa tcttttcata
    24841 ttataaaatc atcctctcat tttttgcata aaaaatagca ctgctattta acagtgctaa
    24901 gtggtatttt tatctcttta gaccaatgct tcattttatc catatctgtt tgatatttaa
    24961 atgaccatgc atagcctaaa ctttcattat agtttttaaa ttgtatctta gtcttataaa
    25021 cattaattaa ttgccaataa gtcattttta aaataacatc tattggtaca tatccatcta
    25081 tgttttgaac tacatttata taatcacata agtgatatgc ttctttttct cttttctttc
    25141 tttccttctc tttaaagtgt gcaatcaact gtttttctct ttcagagcca gtattttcaa
    25201 tccacttatc ttcatcatct ttaaataaat tctttttatc aatacaaaac atctctaaaa
    25261 ttaaatctga tattagtcca aaatcctctc tacttataaa agcatttttc tttttatcat
    25321 caaatttaat taaaatacca attttaatct tattcatata ttcaatattt ttaatatcag
    25381 ttttatataa tatagataaa gattttttta tcttatcact aagtaactca atttcttcag
    25441 aagaatctct tcttgatgtt aacatcatca aatctaagat aggtatagca tcatatttac
    25501 atttcaattc aaatgattcc tcgttacata gctgagaata gctcttttca agtactaaaa
    25561 atggattaac tatctctaaa ttagccatat caaatttaat aagttcttca atagtaggtt
    25621 gatatacagt tcctaatgtt tcacttagct taattggtaa tcctgtaata taataatttt
    25681 ccaacattac atatcaccaa aactttcaga tgatacaact atgctaaatc cattataact
    25741 tgtatctaaa ttaaacatgg gggaacagct ctctaatttt atttttccta tacctgctat
    25801 ttcctcattt tcagtgattg tgtccactat acaacatact aatgcagcat ctcttagtcc
    25861 attaaaagta tcttggcatt catcatggca tactacacca atttcaatat tagtagtttt
    25921 tattattcta cttctatctt tataaagatt atatttaaat aatgttatgt aaacagaaac
    25981 atctgcttct tttaatactt tttctactct tctattaaaa aacactttct tgtttctaag
    26041 ctctttaact ggatttttta tatcaggcat ggataaaata tctttttgtg attcattatt
    26101 ataaatcata aatttagcga agtcttgatt tgacattaga gttgttccta tattacttat
    26161 catcttgtta gggaaagcca tatagaccca tatatctacc cccttagtgt tattttttta
    26221 gtatctatta tttcatttgt atctttatct ttagccaata gcaaggcttc tgagccagaa
    26281 tacttagcca atgtattagc ctgtataaca catttttttt catcttgatt aattatatta
    26341 caatacctat attgcttgtc taagagccat ttaactcctt gaaaatggtc tattatgtac
    26401 tcattttctt ctcctagatt tattacttca taacccataa ttttactaaa aggaataatc
    26461 acactatcgt tttcagataa atcattccaa gctatattat ttattgtatc atcttttgaa
    26521 atcaatgcat cttgtaaaca aatagcttta ataagaccat ctgctcctgt ttctctgcca
    26581 ttatactcaa agtcattaat actagtaact ctaaatacag ttttaccagt taacattatt
    26641 ctagtgtcaa tatctatagt tttagtgaca ggattacttc caaaataaag ttgtcttttt
    26701 gtatctgaga tagaagtata tttattatct gccataccat cagagtataa ggttaaattt
    26761 tcaacagcta tagggatttt atacatctga cctttatatt tataattaaa aaactgattg
    26821 catcttttta ttatgaaatg tttgtatgta tccatttctt tatgttcttt aaatatagtt
    26881 aaccaataac aattatcata gaaaagataa caacccacat ctacatctaa atcagattca
    26941 actaatagat ttttttcatc taaagctctt ttatcattat tagttatatc attaattgca
    27001 actacagctc ttttagtatc ttctgttata caaatttcat ctatatcagt tatttgtact
    27061 tcaatacagg ttggtgtttc ttttaggtat ttcttaaaac ttaatctaag ttgtaatatt
    27121 cttttttctt taggagttga acaaccaagt ccaattcttt tttttatgtc acttaagtaa
    27181 ctcatgctag ttccatcctt caaaattttt tagcatgtat ctttgttgat atttattaaa
    27241 tctagttctc aattgttctt ctcttgcttg aagtttagcc aacatattag cacctgattt
    27301 agcattataa tcagaatcag ttagcatctg ttttaaattt tcttctctat ttatcttagg
    27361 ttgtaaccaa tgtatttgca taccatatga taatatttta atttcctcta aatctaaatc
    27421 agatactatc tctcctaaat atttgtattt gaaaattatc tcttctgtag tttctacaac
    27481 aaaacttatt ataaattttt catcttcaaa gcttattgta taatctttat ctaattcgta
    27541 ttcttctttt gtatcttttc ccatcaaagt tatctctgca tttttattac tataattaga
    27601 tgtataactt agttgagcag caggaataat ttcctcgcct ttttcatcaa catattttat
    27661 agtcaaatct tttttacatt gattaaaatc aactatagca tcttctaaat aactgtacat
    27721 cattttttct attatttcat ttgatagtaa taacatctct tcatcattaa tagcatccaa
    27781 aaacttttta tatattttta caagtggagt acccaaatat tccaccacct ttaactaaac
    27841 aagtacaaat cttctattcc aattctttta gctaatagtt tagcctttag cccagaatca
    27901 aactttttct ttttatgtaa atctattgcc ctctcagcta atcttcttgt taactcaaca
    27961 ttatttttat ttaatatttt ttcaaaagaa tttatatcaa ctttatcaga taagaaatat
    28021 tctaaatagt cttcattagg atttcttata tgttcatata aactattcaa tcctagaaaa
    28081 tctattatgt ccattggggt acattcaaca tctaaagaat ctacatccga aattattaat
    28141 ctatgttctt caaaaaaacc tggacttctt ctcactattc tataaagagt atctaaatct
    28201 ataaattcag ttgaatcttt tgaacctact ttagataaag aaaaaatttg ttgtttttct
    28261 cttgggtcaa tataatcaac atcccatgtg gatatatttt ttatttctat atctatttcc
    28321 tgtttttttt gttttagctt tctttgtagt tctaatcggt ttaatctagc ttctttttta
    28381 tttaaagtag actttatatc tttttctaaa gtattagctt tgacttctgt tttagaaata
    28441 ttttcttttt tagctcttgc cataataatc tccctcccat aaaaaaagaa ggtggttatc
    28501 caccttctaa ttcaattatt gtattttata aactccaaat ttagcagcag ttacaactcc
    28561 taaatgtatt ttttgagcca taaaatattc tatttgttgg tcatctcttt ctttttcatc
    28621 agtattttct atgaccaata catctccttc agtaccaagt ttgattatct tctctccatc
    28681 aggtattaca tagatagcct tattatctaa agcccactct ttaccttctg ctgcattttc
    28741 atcataagca tttggtaaac taagtacttt atatccacct ctaaatgttt gtataaaacc
    28801 atattttctt ttttcttctt tttctaaatc agtttgaaca ccttctaaat tacttaatgc
    28861 aagtggagta ccatatataa taggcttttt accagtagcc ccttctacct tagctatcaa
    28921 ttccaataat actttgtctg aattacctgt agcttgaaac ttagcattta ttgttgaata
    28981 tgcaccttca aatgtttttg ctattcttct agcaatatca taatgatatg aatctgatac
    29041 cctattcaca aatacaaccc aatttattct tcctgttata aatctctctg cttcttcata
    29101 tatagcaaca gataatttaa atgctgttgt aggaactttt ttgttaagta atctttgtct
    29161 tcttgtacta ttaacaccat ctgctatatt tgcaacttta aataaattag tattttcaac
    29221 agtaaattct tttttatctc ctaaatcaaa attctcaaaa tcacaaaatg gactaaatac
    29281 ttcctcattt aatctattaa tatcatcaga tattaattct gatattaaat tataaaatcc
    29341 ccatttattt tcttggaatt tataataatt atatttttct cctcccatca tttcttttaa
    29401 tttattcttt attgcacttt cagcatctct atatgttatt gtgtttccat ctctatctgt
    29461 atattctcta aatgtatctg tatatagctc atgagctatt ctctttaaag tttttgctgt
    29521 tgccattaat ttacacactt ccttttctat ttttttgcat aaaaaaataa cagttataga
    29581 ctgttatctc ctgtttgtta attttatttg attttataaa acttttattg taaccgaatc
    29641 ttgaccttca tagttccata attctaatac ttctgctact ggagttttag catctgctgt
    29701 aggcaatttt tcaaactgaa acgaatcaga ttttaattgt aacttgtctt ttactgcaat
    29761 acttttatct gctatatgta atagagatat agttacctca tctccttttt ttagtcgtct
    29821 acatctacat atctgaccag gagaaacttc gtaatctctt tcatctaatc tttcatcata
    29881 catagttgct gggtcatcaa ctatacccca atctaatgtg tcatttgtaa ctttatatat
    29941 tttatgggta tccctaccat actccgtgtc ttcaagttct ccaatattta ttacagcacc
    30001 attttctaaa tttattggat tggtatcctc tgatggaaca acatatttac ctgttaaaac
    30061 atcaggattt tttactttat ctgtttgtat tattgcttta tctttcttca tgtaaattcc
    30121 tcctattatt ctttatctga atattttttt ataaaagata tttcttctgg ttcactaaaa
    30181 ctatcattat tattacttat aggtattttt atcgtattat ttttatcatc atttatacta
    30241 aaattttcct tttcgctttg tttattgcta agagttttta atgcaaatat gtaacccaat
    30301 tctttcttgt attcatctaa tgtgatttcc ttattataag cttttatttt tatatcttta
    30361 atttcatctt ctgctaattc aaatttttga gctacatcat caactttaga tttaaataac
    30421 tcaaattctt tttcttcttt gaatgcctgt aatggctcta aactggcttt taaattagat
    30481 atttcttttt gtttttcagt aaatttctct attatttctt tttttaattt ttcttgtcta
    30541 ctaaaaacct gtactatttc tccttcttgt ttttccctcc aagtttgtat atatgatttt
    30601 ttattttcat aatccaaaat gacagcatct tcattaacta tatatggaat gccataataa
    30661 tacccccagt taatttcatc ttcaactata gcaatattct cttctggtat taaatcatta
    30721 taataaaaag cttgtacttc aactttttca ccataccaat tctcagtttc gactttgtat
    30781 tcttttaact tatttcttat ttcagtacta agattactca ctgctaaagc atatccttca
    30841 gaatttttat taagtttttg attcttattt ggcaaattct tttccccctc tccatgttct
    30901 aatgcataaa tttctgagca tatttttgat atttcttctt tataattaat ttttcttgaa
    30961 aatttagtta aacaacaatt tgaacccata gctcccttta catcagaacc aagacatgta
    31021 attccatgat atacatagtc ttttatatta taaaatccat ctgaatcatc taattgataa
    31081 tcatttatat ctatttccat tgaaatttct atttcatcag aatccataat tatatcgtaa
    31141 gcatgattgc tatatgattt atatatatat cctttacatt taacatactt ctgcccatca
    31201 atttcaactt tttcatattt atttgtttct ggtataacgc caattattcg ttcttcataa
    31261 tattcttcta atataaaccc ttcatctgtt tgaactactt gtgttaaaac attatgacca
    31321 tcaaagtcat attttccatc ttcatttatt tttacatatc ctagaattgg aacatttttt
    31381 aatgttggtt cagctttatc aatagcttct tcataaaatt tagttccatt tggatttgta
    31441 ccttcatgca taacatagat atacactggc aaaagattac tatttagttc ttccaatttt
    31501 tttttatctg aataatgttt taaattacaa ggtaatttta atatttttat ttttttcacc
    31561 tccttttaaa aacgtatttt gctagtaaat ataaatcttt tcatttcttc attactgaaa
    31621 ttatttatta attttgattt attttcaaaa acatataaag tcttattatt caacttgttt
    31681 tcacatataa aacgatatcc tttttccatt aataatttct tatcatcttc agaaaaagca
    31741 tatataaact tactcataat taatcattct ccccatttcc ttttgcttga gtagaattac
    31801 cattatctgt ccctatatca gatttatctg gtctaccact gctttgagta tgagatgttt
    31861 gttgaggtat taaaaactca tcaaatccca ttaatttttc tgcttgtaaa gtgtttatag
    31921 cttgaagtgg agtaaaccca gtacttgcaa taaacaagct tttactccct ccgtatccca
    31981 tatcttctcg atactgtttg gataaattca ttttattaaa gtgagtagtt ccaataaact
    32041 tcatattaaa taaatttgcc ttcttgtctt tatttagttc aaagttaacc caattttcta
    32101 tcatttgttg aatcctcata ggaattaagc tatctgcaat aataccattt aagatagatt
    32161 cattatttat cttgtcagag ttaagtaagg ctgtatttat tccagcgtta tcaaatataa
    32221 actcttttgc ttcttttaca taatcattta ttttagattt tccatctgaa agagtatgtg
    32281 tttccaactc taaaggattt gtagttattg ctgttccttt tggtaaattt gcttttgttg
    32341 aattgtggta tatgggaatt aaattaaggt ctactagtgg ttcatcattt ttgccaaatg
    32401 gtatcttttg atgtattaat ttaatacttt ctattactgc atttgtgctt tttaaatctt
    32461 tcatatcttc aagctccatt aaatcgtcaa atataaagca aaaaaatgga actcctttca
    32521 ctgaatctaa atcataatta aatgctactg ctttatcact taattgaaaa tatgtattat
    32581 caattaattc ttctcgtgta agtaaattag atttatattt tttatatatg tttttaattt
    32641 cttctggaaa ggatattatg tttttgtcag taagtttttt tatatttata gcgtatctca
    32701 ttacattatt ttctatcatt gttatcatac aaaattttgc tggtatctgt tgtaaaacca
    32761 tccctgaatt atcttctatc ttatataaat aaacctctcc taattccaat actttttcgg
    32821 ttatccaagc tgatgtaaat tttatattat atttttctaa ttgactcgcc gaattcatat
    32881 atgcttttgt tattttttct tttgttttta atctacttat gtcttttggg tataagatat
    32941 ggtcaaaagt attcatatta gatattaaat ttaaaactct tctatatgta ccagatgtag
    33001 cttttaatat catacttgca tcctgaagta tatctgtatt tgaaatttga tatggattgg
    33061 agagagcttt tcttaatttg tctctactta tacttcttaa cttatacatt tctgttgcta
    33121 atgttgtgga ttcttttact gaggcatatt ttccaatttg agcatttagc atattgattt
    33181 gattttgtgt agaattgttg tctttagact tgcttttatt attatttttt ttgcccactt
    33241 attcacctca tctcttacca ataaatcata acagtttttt gattatttct attttttctt
    33301 ttctcttttt cttccagata atctgctaag aaattcgtat aagccaaact agaatatcta
    33361 tcttttcttg ctccactttt ttcctttatt ttaatttttc ctccatcagc actatattct
    33421 aaatttatta actcattcac taaagccgtt gtttgaagat aaggggcaat atattttgct
    33481 tctaattctg cctttttatc tatttcatct gcctttatca tttctttttc taatatcatt
    33541 tcttttgctt caatatcact tataggaagt tctaaggttc tatttgtaag gacatctctt
    33601 aaagacatag ccattttatg attttcatca gcgtaagctt tcatggaata tacaacagga
    33661 agtgattttt ttgctagtga cttgtcaaca gtattatctt cattaaaaca tgtgtaagca
    33721 tcataccatt catctctatc tgaatcataa tttgctttct gtatatagct ccatacagtt
    33781 gttcctatac cttgtgtatc taatatcata taatctgcct gaaaatctga aaataattgt
    33841 tttaatctta ttgcttgttt ttcagcttcc ataccattat aagcttctat atggacaaca
    33901 catcttttat atgtgccttc atttggaagc atcctcatca aagtataaat agaattatca
    33961 ttcttaactc ctctggctaa agctatatct gcaccaataa tccgtatttc tccttttatc
    34021 ttattaagat gatatttctt atctcttttt ttcttatttt caagatactc tatatcacta
    34081 ggaggataaa acatactttc taatacccta catggattca cccaagatga cttgaagaaa
    34141 gcatcatctg attcattata aaacactcca caatactcca tcatgaaaga agcatcactc
    34201 atactctctt ttttcatttc tttaagtatt ctttttttag ttaatagtcc atgttctaaa
    34261 gagcaagtga atggaatact acatgcaaac atatcttcac cactaagcat accttttact
    34321 gtttccataa actttttata actccaatgc tgagaatacc agcctgaact aagataaatt
    34381 tctttattct cttcttgcat atatctatat ttaggattct gtaaatatcc tggttgtctt
    34441 gggtttgtta aaaatggaac taaaacatca ttcacagttc cttcatccac cattctatat
    34501 tcatcaacaa taagaacatt agctctgtaa cctcttgcat catcattaga tacaacagct
    34561 tctattctac ttccattcca aaaatctata gatacttctt gtgcatttac ttggaaactt
    34621 ttaatttctc ttttcagagt atctgatttt aaatataaat cacctaaaat tttacttgta
    34681 ataagtagtt ttgcttgttt ctttcttttt gctgctatta aaacacaagt acctggtttt
    34741 aatacagcta taacacaaca aaacactcct agaagccatg attttcccag tccacgagaa
    34801 gcaatgaata caaattggtc agacttcatc atcatataaa ttaatatctg ttgaaataaa
    34861 tgtagattaa acccaaagta atccatacag aatctatgtg gatttgcgag ataaaaagca
    34921 ccccaatact ctcctatact ctctagtaga tttcgggatg aatcattaga tgacagctct
    34981 cttttttcat atttagtcct catttttatt accttctaaa atgtctctta catcatcttt
    35041 aaatttaata tctttatcgc catcatttat cgaatactta cctgtagcca aacctaatgc
    35101 aacagcaagt ggttttttca tatgtttatt tacataagct tcaaatccat ctacatcttc
    35161 atattccttt aacctatcct ttacaggttt atttttttca tatatcatca ttttcattcc
    35221 aaatgtatca tcttgcgaat ctccagcttt ctttttctga ctaggcttta tttcagcatc
    35281 ttgcatttta cttgatacta atttagataa atcattaaaa gctttcatat ctcccttttc
    35341 tcttgattta tctttttcta attcaataat acaaatctct tcaaacaatt ttctttcagt
    35401 taatgactct ggttcataat attctttata ttccttatat tttctttcta agattttata
    35461 ctcataatca tcaaaacctc ttccccattt taatttaatt tcatcattta tgactatatt
    35521 tttatcatta ttatttcctg tatatatttc tttcaataaa ttatctaaag atgtctttcc
    35581 cttatatttt gaatttctat taataatttt catatattca tctattaatt catctttatt
    35641 ttttttatct gcaagttctt tagctaattt ttcatcaaaa taaacatcaa agttgaaaca
    35701 tatatgtttt agtgccttta caagttctcc attgtaacac ccatttaata gtaaaaacct
    35761 agctctaaaa cattctttgc atactggaag tcttttattt aaagtaaata tttcactatg
    35821 acttttccaa aaatatctat ctgtatattt ttcttcacca caattcaaac attttgtttt
    35881 actaattgcc attcataaca tcaccaccat taaaaaagac cactagagat ttaattctct
    35941 agcggttaat agggagattc aactcaatta agagctgagt taaatttaca atataaactt
    36001 aactcagctc ttaataaata acttatagct tacttaaatt tatattgtaa gtacatattc
    36061 tcccactttc attaaatatc attaattttt gcattgcgtg tgaacttaat cttagattct
    36121 tagcataaga atccgttccg gagaaacttc catttacaca tatttcactt tctccataat
    36181 tatcttcctt acaattgtgt agatgagcca taaagatata atcaggaatt aattttataa
    36241 gagaggtcag tttaggaatt gctgtagaca ttttatcttt atctccatgt actgcgaaac
    36301 atgtatttcc acatatttta gctactatta tgtcattatc atatatattt tcttggaata
    36361 ttacattgcc taaactttta attcttagct ttatatattc atctattaat agtgtaaaat
    36421 tatctttatc taaattttca tcttttttag gaagaactct atcatgattt ccaccaactg
    36481 aataaacaat aattttatca atttctttag ataattcata tataaattca ctaagtattt
    36541 cagatacttc tataatttgt tcaactatat tttctctatt ttctaacctt atagaattat
    36601 ttgacactct cccctagatt tatctatggg gattcttggt gactaacgca cttatttata
    36661 cttaaacagt aaaacagagg tgattacaaa gccaagctac ttggacggtg tcttcgccac
    36721 tactacctta tatagtagat acttttaaat taattggttg gttgtggttt attttaaaat
    36781 caactaaatt atatttatgt tttttattta aaatattcca tgcaccaact atatctctat
    36841 gagttttata accacaagta caactatatg ttctgccttg tggtttgtgt tttttagaac
    36901 actttgggca agtttgagaa gtgtagtttt ctttaactaa cttaacttct attccttgct
    36961 cttttgcttt atatttaata tagtctttaa tgcgaccata ctccatttga gatatttttt
    37021 gtctattaat tctatttaat cttttcttct tttttgtatt tttctcaatc ccttttatat
    37081 ctcctaaaac tatttcacat acttgttgtt ctacacaaaa gtctataaac tttctcgttg
    37141 tttgatggta taaatttatt aattgattat ctgttttagt tctaatagtg ttttttaatt
    37201 tccataatct cttatattgc ctactacctt ttttacatct acttaatctt ttagatatat
    37261 aagcatacat cttatttcta aattgtttaa tacttctacc ttctctatta gatattataa
    37321 atccgatacc ttcattagtt atactagcta tcgaatgtat ttctcctaag tctacaccta
    37381 ctgtgttgtt acctttcggt gttggattaa tgattccatc atcaaatgta taatacaaat
    37441 aatatccgtt tcgccatact atttcagcag tctttatatt ttcaacatta aaatctaact
    37501 ctaaatatct acctgcactt aatgttaatt ttaaatttcc ttgcttatta gttcttatat
    37561 cttgattttt caatggtatt atatagaact ttttaatttt gtatgggtac tttgcttttg
    37621 aattgccctt ttttctaagt tctgatattg tttttctatt cgcacaaaat tttgttgata
    37681 tagcttgaat tgtttgtcct gataaattaa atttaccttt aattagtttt tgaatatcat
    37741 aattagaaat ccattgttta tgttgaaagt agtagttttt tgataaatta attatgtaat
    37801 tccagcagtt agcactttcc atttgcttct ctcttactag ttcaaattgt gatttagtta
    37861 attttaattt aactctatgt gtttttatca tttcttctta gtcctaactt taatgtattt
    37921 agaatttaaa atactttatt tatatcattt tattttatac aatatatcat atcaatgtac
    37981 ttgtctaaat aagcagtcca tagtcctcct aaaacccacc tctgccttca atttatatat
    38041 ctcttcaaag tcatcttcta tattaacaca tctattcaat aaatccatat acctacatat
    38101 gacatcaata gaaactctct caaagaacaa ttcattctca attatgtatc ttacattctt
    38161 caaattataa tcttttacat tatctaagaa cttcttaatt ataactaata agttactatc
    38221 ttgctttaca aaccttatca tttcaattct ttgttcattt ctttctaata tattcccctg
    38281 aaaccttccc acagccttga ttatactcat acccagtctc cttatattaa catttgtatt
    38341 ttttataaga aacctcactc tttgtctaaa gtttgtaagt cttcttttta attactaaaa
    38401 gtaattttat cacttaaagt aatttatatt tttataatac actccacata atgtaatgtc
    38461 aagtataata ttttattact ttatgtggta taataattat aaagatactt ggaggtgaaa
    38521 aaatgtttgg agaaagatta aaagaactta gaattaagtt tggattaaag caatatgaat
    38581 tagctgaaat attaaatgtg tcacaaagta ctataggtat gtatgaaaat gaccaaagaa
    38641 ctcccccagc agagtccata gttaaactag ctgaatactt taatgtcact acagattatc
    38701 ttctaggtca tactaaaact aattattcag ttgatacaga caaaacaaaa attcaatcaa
    38761 tcattgattc tttagcttca tatgaatcaa ttaaatttcc aaaggaaaaa tttagctctt
    38821 tagatgaata tattgatttt attaactctg atgaagatat taaagaaaca ataaaaatgt
    38881 atataagact agataaggaa gacaaaaaag ctataagaag aattatagaa aattcattga
    38941 agtaataacg aagaggataa agcatactct tcttctttat ttgctatagt ttaatgtgat
    39001 aatatctccc taatattaag taaaaataaa tagtccaata ttgatttatt ggactattgt
    39061 ttcacttaat cttattgtta tgtttaaatc tgtttttcca atatactggt caaaaacatc
    39121 actagataac acttcattat cgccattttt tgtatgctct ataaatttat aagtaccatc
    39181 ttcttgtttt attacttcac atttttctaa aatcgttcct ttattatttt tcatatattt
    39241 tctcctttat ttttatgtta tctatatctc tactgggaat atatttattt gcaaattagg
    39301 cagccttgta gctaacaata gctaatataa gttaacgcat ttagcattta tcaaggattt
    39361 tctataactt ttttatttta tttttactat tttaataatt taatctttta tccttgagat
    39421 tttatatttg aatttttaac tttaagcttt atatctattg ttctctttta tacagtacaa
    39481 tcgtttcgtt tgtatgtacc catcactttt atataagtag tttgattttt aacccaaaat
    39541 caactgggaa cttataattt atgttattcg cctaacctgc aaattaaaaa atagcccaat
    39601 taaggactat tttaaatcta catctataat tgtaagtgca tttgatgtac tcaatgcaaa
    39661 atcaacttct ttttcaaatt cttctatttc atcccttaat ttttctattt tctctcttac
    39721 ttttaaaggg tctactaaag accattcttg ttgtttttta taaaatgaaa taagttctgc
    39781 tccatcttta cttttttctt tttcctcaaa cattctgtct gtattttttt gcacttcttc
    39841 atttctacga tttacttcag acatcataca atcatagtta ctaaccattt gtctcaacaa
    39901 ggatttatct aattctatac tattttttct ttttattgct tctaaaactg tataattttt
    39961 attaccaatt tgaacatttg ttatagcatt agagatatta attgctttat ctaatgcgtt
    40021 ataattatat attaaatctt ctatttgttg gtatctactt gaaacttcta cattaaaatc
    40081 ttctacactt gtttttgttt catatacatt tttatcagag ccttttttag tacctacaat
    40141 tttaaaatta ctaatgcatc tatctatctt atcttctaat aacttctttt ctgctaaagc
    40201 tttatgaaca ttatatttaa ccataaaaac atctcccttt taattaagat attatttaaa
    40261 aataacaaac tttttttatt ggaagagagg aagggatttg aaccctcgta tcaaattaat
    40321 tgacctaata gtttagcaaa ctatcctctt taccacttga gtacctctcc atatttctat
    40381 aaattacaaa cagcaagtcg agtatcgcta ccttcgacca tggtcaagtg ctgtatttta
    40441 aaactccgac agctcggata gcgtggctgt tttttcacac taaagaatct tttttaattg
    40501 tccactattt ggtagaacat caccactttt ttataaataa atccacataa aaattactta
    40561 gttcaaaaga ctatttgatt tattcacaat ttcttcagtt ttttattagc caggtacacc
    40621 aacaaactcc tctaatttta aaaagcagaa gtagaatctg ttacctcaaa ttctacttct
    40681 ttattcttac acctttaagg catactaggg cattcaccgt atctatttca agttatatgt
    40741 tgctcatcaa cctcgtgtat atttgccacg ctatattcat tttagcagca tcatcatctt
    40801 atatttgtaa aatacctatt accagccact agagcttctc aaaatgagct atctctgcta
    40861 attgtattaa tttttagcat attctaggtt tgctgccata tgtcaccata tgaaagggat
    40921 tttaacccat acactctcta tatgattgca tcttttaaag atttagctat ttttaatttt
    40981 ggaactcttt tttcctcagt tttccaaggt tttttagttc catctttaag agttatttct
    41041 ccttctttac ctttttgtat tttagttagg tatttaactc ccatcaacgt caattcttca
    41101 ccatcttgta gtacttcgtt tctttttttt tctatcacat caagtatctc tcttactctt
    41161 atctgtgata cacctaattc ttctgctact tcttttaaaa aatctacttt tttcatatct
    41221 tcttaatctc ccttttctta tataattttc atttgataat agtaaggaat aattttatta
    41281 tttttattaa ccccttacat aagtaatatg ttttaagcga ccctttttta aaccactttt
    41341 ccccaccagc taattacagt ttttacaatt tgagcgatat ccctttttac catttttatc
    41401 aaacctagat agcaacttaa tttttccaca tctgctacat tttttatatt ttcctttaca
    41461 aacagatata taataataat tttcttcata gtttttctca tatgcatcta ttattttgtt
    41521 cactatttta tttatttgat tatttattgc ttgaggagtt atattcatta aatttgaaat
    41581 aaactctaat gatttatctt ttctatataa atttaaaata tctttttgta ctgtggtaaa
    41641 ctcaatttta gatataatat tatttaaatc cataactata catgttaaat catcttgcaa
    41701 atcattaccc ttttgaatct ttaaaagctc tttaacatgt gatttatcaa acatatctaa
    41761 atagtcccat tctgggcttc ctgcatctgc taatggtgct ttccatataa ttggtctctc
    41821 tatagaattt ttaacatcag tcatatcatt ttttaatgca tttaaatttt tcctaaccat
    41881 tctcttaagt tttaactctt ctttacttaa ttgtttatgt cctaattctt tatatttagc
    41941 tttataccat tcataagtat ctgagtatgt ttttataatt ggatattttt taatatcttt
    42001 aggtttaact tttatatctt ttattttttt atagttttta ggtaattgaa aaaatgcaaa
    42061 ggaattgtct tctaggaatc catctttatt agaagtgttt gaatttatat ttccaccatt
    42121 tgcaggtgct attttattta gaagtgcttc ttcctgacat gctctatcaa ataactcttt
    42181 tgaattgtat attcttattt tagtttcctt aggtttatca tctactgaga gtatatagct
    42241 ccccattatt tctaatgttt ttgctatatt agaagtagaa tatatactgt catctttatt
    42301 taatatcaac ttaattttcg atgtattatg atgtgtgtac tcccatgtac cattactatt
    42361 actaaaagga tttttaacat ttatatattc gattggatta atttgattat agccacacca
    42421 agtaatgaat ctattataat ccataactac ttcttctcca tcaatagtaa cataatatac
    42481 accatcttta tctaaaggac tatctgatgt ttgctcaaat atattttccc aaaatttatc
    42541 attgaattgt tttttttctt gatatttcac tctagtaata atattctcat ttctctttgt
    42601 aagagtatta taaaatgtat ctatataatt tctatttgac tcttcaaacc acgtgtgttt
    42661 tacccctaat cgttcctcta tgtatttaat tctatctttg ctattgtcta tgctataatc
    42721 taaattcttt atgtaatctt gtgcagattt gccatctatt tcttcataaa aattgttatt
    42781 attatatatc aatattatac ctcctttcct tgcaatccat catcataatc tgtatcatca
    42841 taatcccata gttcatcctt aaaatcctcc ttatgccttt catttacaat atcatatgaa
    42901 gaccttttac tcatctctgt gtatgtatct atcatttgtt catattcctc atttaatatt
    42961 tgatacctat ttttatgtac gcctgttttc tctgattcat ctaaatcttc taaatatatt
    43021 aattctattt ttttctcttt catacttctc cttttctata ttataagatt ttaaattaat
    43081 tttcttggtc acatttctgt gccgtttttt tgccttttgg tcacatttct gtgccacccc
    43141 taaatttaat tttttaactg tttttcctat atttttgtta atttttacag ttcattacct
    43201 cttattctta gacagacttt ctaaatacaa ttaaaaaagc ataaatcaat tgttttcttt
    43261 gctaaattta aattatttcc cttccatatt acacaaggat ttataatgaa atagtctgta
    43321 tttttgttat tcccttcaac gattacatat ttaaaaaaat aatatttatc atcttctacc
    43381 tttatataaa atctaagtaa ttccttttta aatttgttca tatcttgttt tattgtacta
    43441 atatttaata attgacaaat tttatataaa ctaatttttt ttatttttga aatatctgtt
    43501 tcatgagggt ttaaacataa gatattactc tcgaaatgta tatatggtat gagttgatat
    43561 atataactta attgtttatg ttgtcttggt gtgcaatgtt caaaaagaaa tctactagta
    43621 tttatatata ttcttgtata ttctttattt tcaaaattag gaattccttt agtaaaatac
    43681 tttggattta tataaaattt attattagat tcatataata actcacattt ttttacgtct
    43741 gctaaaaaat ttctaaatgc cctatcttta agatttaata tttctctcat gttttttcta
    43801 tctataggaa tcatttcttt aaactgagaa tatctaacca ataaattttc ttctcctgta
    43861 ttatagttta gatatgttgc gagatatatt aatctactta tattagcttt acttatattt
    43921 acttcattaa ataataattc atttttaaca taagtacaaa atacaaaacc tcctaattta
    43981 aaattatggt atggtaattc ttttttatta ttgataatag ccctttgctc tggagaaaaa
    44041 ctcttttttc tctttccaat ttcaagtacc tcacctcttt tcatcccttt atgctccaat
    44101 atttctcctg ttcttttgtc tgttacaata acatctttta taaattcatt acctctaact
    44161 ataaatatct acctcttttc ttataaattt tatttcaatt acaagataaa aaccatcttg
    44221 caattgttct tcgcaacatg ttgcttcaga aattttatta ccctctatgt tctatttcta
    44281 ttatatcata taccctctat gttctcaata ttttttttaa tatctaccca aaatttcttg
    44341 agtagatatt ttcttttaat ctggcatatt attaaatata ttcttaataa taggattttc
    44401 tctttttata tctttttttt cttcagtaac atttgtcttt ttatttgtcc tatatacacc
    44461 attgcctaaa cattgtttta ataatttatt ttcttcttga agatttttcc actctaatat
    44521 tattctttcc aaagctgtat ttctactgct tatattttta tcattttgat acttttctat
    44581 ttcaccaaat atatcttctt ctaaataaaa gctagatgat tttttcatat aatatcactc
    44641 ctagaattgt tccataccta cttcaaataa tcctttagct gtagccattt gtgcatcttt
    44701 agaaacttta aatctattat cgaatgtcat atgtaatgct gtacctccac ttacatatac
    44761 atccatttca tctatgttct tccatttaga agatattctt tgagctgtgc tttcagaagc
    44821 cataatgtaa gcaactttct taagttcatc ataatcatta gaactatcta tctcattaag
    44881 ctctcttatt attcctctat cttttagttg cttctgaacc attgttaaag catcttgatt
    44941 tccagcttct aatgtgtctg atagtttatc attaaataca aaaccttttt caaagaaaga
    45001 catctcagta cttctaaaac ctattgaaac catgccaacc gctttatctt catttacttt
    45061 tccttctaat gtatgaaata atgcagcgtc tccttctcta aaaattgata tatcagatat
    45121 ttttatttct ttatgtccac cttttatttt atcttttact ttaaatgttt tacctttata
    45181 tgtgtctaca acttctttta atgttgtttt cctaaatgat ttatatggaa cgcccatcat
    45241 taattttact tcatcagcta cagctatttc attaagagca gcagcaacta atattctcat
    45301 tgtaaaagat actttagaat catcagaatt tcttataggt gttatacttt ctttttctgc
    45361 taatgaacca acaaagtaac ttacactttc aaaatctatg tatattggat tttcatattt
    45421 ctcaaaatct atgtttcttc catcaccaaa tactgatttg aataaacatt ctttaaccat
    45481 tccattgtac ttactatatc cttttacgta tcctcttcct atatctaagc ctataacttg
    45541 gtaattttct tccattttca ttcctcctaa gtaaatattt gctaaatata ttataccata
    45601 taaaaacttg ataattacat taaatttgca caaaaattca actataaaat gacatttttt
    45661 agttattagt taaaattagc actaaattag aactatatat aatttaaatt taaaccaata
    45721 atttatcatt aaaaattttt agttaatatt taaattatat atcaactatt tccaaaccaa
    45781 taaatcaatt tctttaacta cactatttat gtttttttag atgtcaattt taattttaag
    45841 taaaatattg aaacttattt tcttacagac gacattttca ttctaattta ataaatcttc
    45901 ctatatttca agttattttt tgtatttaat atttttatat gtattagtta tttttatgta
    45961 atcaatacat acacttttat tttatatttt ccttgttgag aatgtaattt aagagtaaaa
    46021 atctaagaaa tatctttaga taaatatttg ttttatgagg aaaatacaga gctatttcgt
    46081 ctgtaaatcc gtctgcaatt tttttgaaat gtggaaatga aaggactaca cacaaaatcc
    46141 tactgacaaa caagccactt tccataaaat accccctact tcatttttat ttattttaat
    46201 atgtaaaata ctttatttac tttatttaat taataaaagt attactttta tcttatttta
    46261 aaaatctatg tttttgtcag taaaaaagga cataaaaatt agtattttat gccatttttc
    46321 taaaacctag cattttcaat acttacaaca cctatacttt ctattttgtc agtaaaatgt
    46381 cagtcattat aattcttaga ctacaaacct gttgtaatca ctgtatttca atttttagtt
    46441 attgatatct atataaaata ttatttgcta tagaataaat ttttttatta tggattataa
    46501 agtcttatat acatcatttt agcattaatc tgacatcgtc gaatatcaac tcacaacctc
    46561 attgccatat ttttcttgac aaatttgtca ttattgtata taatttaatt aagataagaa
    46621 ttaatcttat ctatacaatt caatattagg gggtgacgtt atgagaataa caaaaggcaa
    46681 aataaaagag ctaatcgagt tgtgccacca acttgaaaag ctctttgtac aagtatttaa
    46741 atcacttgaa catattttga tttctttatg ttcttgtatc ggttggttat taatacttat
    46801 atacataatt aaacattaat aaccaatgca atatacctat aaaaatatat ctctataggt
    46861 atattgtaac acacctaata ttgaaagtaa acgaggtgac gacatgagtc aacatattaa
    46921 aaacacttta aaaataataa agatactagg tttattattc ttcttatatt ttgcacttag
    46981 agcaatatat attgtttatc tttaatatct ttattgagtt gcttaatgta taagtaactc
    47041 ttttttgtta taatattaat gaggtgatag catgaaatta gaaaaattaa ttgatataag
    47101 aaaagaaaaa aaatattctc aagaggatat tgctagaatg ttagacatat ctttaagaaa
    47161 ttatcacaga aaagaaaaag gagagaatca atttacagta agtgaactag aaaaaatatg
    47221 tagctattta gatatagaat caaaagaact acttgacata tagtaatata atctactcaa
    47281 ggtagtactt aacattaaat aaaataattt aataatataa aatagactag ctataatcta
    47341 gtctatttta ttataataac atattgtaca agccatttaa atccattcta agcacatttc
    47401 aatgcattca ccttatgttt atacctttaa tctttaaaat taaatataaa aataagctag
    47461 acatatatac tctagcttac agtaattttt ttaatgtgtt gacttgttct tgtactattg
    47521 ttttactctt agtgtctaac tctctataat tatttaatag ttgtttttct tcttcttcta
    47581 gttgtatatt ttctctattg tctgtaagac ataatatata atctatactt acattatata
    47641 tattagataa ttttataagc gtctcattgt caatttttct tctgtttgtt tcatagtttt
    47701 gtattgttac ataatgtacg cctaatagtt ctcccacttg ttgagttgaa tatccttttt
    47761 cttttcttag ctctctcaat ctattcatta aatcacctct taattctaaa tataacatat
    47821 tataaattta attacaattg tattcaaaac ggtatgtttt atatatgaca ttatttaaaa
    47881 cattttgttt tgttttttat attttatatt gacaatcaaa acattttgtt ttataattaa
    47941 atcatagcaa gggagaacaa gaaaacacaa agccacctct caaatgaagt aacaggcaaa
    48001 gaaccttctt aaaactctag ctaatatctt aaagggttct attaaaaaat attaaactac
    48061 tattaaaaaa ttactacctt taagttgacc ttttaaatgg tgtgaatggt gaaaggcaca
    48121 caacacaaat attgcacata gttttttctt cattttttaa ctacaaaaat gaattagtca
    48181 taccagttgg tgaggtgttc ccaacattaa gtaattaaat aaataaaatt aataaaggtt
    48241 tccaattaaa gcctacaaaa aattgaggta tcaacttagt tgcttctata atggcactca
    48301 atacaattta atatgacata gcagttgtga ggtactgcgt tataaaaagt actaaagatt
    48361 gagcattaaa attatagttt gtactgcttg acacctacat ggttataaac tatttaatat
    48421 ttactagtat aatttaaact atttattaga ttattttagt aagtgttaga atacaacact
    48481 taaattatga tataataata aaataggagt gtgaacggca tggatgaaaa aatattagaa
    48541 ttattacaaa aaatggatac tagtattaat gatatacaag gagaaataaa atggattaat
    48601 actagattag atgtcatgga aagcgacatt aaggacttaa agactggaca agttgaaatt
    48661 aaagacgact taaaagaaat aaaaggtgat atattaaaat tagatttaaa aacagaggat
    48721 acaagaagaa atataaaact tatgcaatta gatattaata aaatagaaac tattactaat
    48781 tataatctga atgacattgc aacacttaaa gcaattaaat agtaatacat aaaaagacac
    48841 ttgaattatt gagtgtcttt tctacaagct cttagtatgg tattattaaa caataatatc
    48901 attggaggta taacgaatgt atgagcagag aaaagcaaaa gtaatattca ataaaggagc
    48961 tggtaattct aggggagaat catatacgaa tagggttaca attccaacta catggataaa
    49021 acatatggac ataactaaac tagacaggga agttttattg acttttgatg gtaataaaat
    49081 agtaatagaa aaaatagatg agtagataaa aaatctactc aaaaaaatac ttgacaactc
    49141 gtgacgagtc gattataatt aaatcataaa ataaaatttt ttacaaaatg actagtaacg
    49201 agtcagtaaa aagggaggat ataaaaatgc taaatatata cataactaat ttagggaaat
    49261 ataacgaagg tgaactaata ggggaatggg ctgaacttcc aataaacgag gaagaattac
    49321 aagaaatatt agatagaata gggataaatg aagaatatga ggagtatttc ataacagatt
    49381 ttgaaacaga tatagaaggg ttagaaataa gtgaacatag caatatagag caactgaatg
    49441 aattagcaat gaaacttgag aggttagaag aatatgagat tgaagagtta aaagctttac
    49501 ttgaacgtgg atacattgat ttttacgaca tgattgaaag tgatatttgt agcttatcag
    49561 ataattatac ttttatacaa cttgacgaca ggtcacaatt ggatgatgaa aatttaggac
    49621 gtagttacat agaagaaata tattgtggtg atttatctta tatagaaaat attgcttact
    49681 actttgacat agaagcattt tcaagagatt tacgttttga taaagacatg attattgaaa
    49741 atttatacga agaagatata gaatattatg aaaatatgac agatattgaa tttgcagaga
    49801 attatattga acgattagga gatattgaag agttaggtca agaaacactt gaaagatact
    49861 ttaattatga gctatatgga actgacttac gttatgagaa tatttgtata gcatcaaatt
    49921 atttagctat agtttcttaa ataaaaagtt ttagggcgtt ctttaaaaac gccacttcca
    49981 ataaaaaatt gaaaggggaa taaaattatg aaaaaattaa taatcaagat aaaatcattg
    50041 tttaaaaagg atttagatag tagctattgg agtactacag aaagtattat tttaaaatgt
    50101 ggaaacagca atcaattaga attattgaaa caagctaata aattataagg aggtaataac
    50161 atggtcaatt attctgaata tatgactgca acagacttaa taaatatatg tgacctttta
    50221 gaaggtaaaa taataggaga agcaggaact tataattctt tatatgtcag actaggaaat
    50281 ttaatcggat tagattgggc tttaaaagga ggagaattga gacagcaatt aatacaaaat
    50341 attaataata tgatgtattt agataataaa aataaaatgc aatataaaga attttaagta
    50401 aaaaataatt aatttatagg aggaaaataa aatgaaaaaa ataataaatg gatattcaat
    50461 atataaagat ggaacatggt gcgaagtaat aaaagaagga aaatttatct ttgctggttc
    50521 tgtaaatgaa aaactatcat atgaagatat atatatagct ttaactgcaa agttagaatt
    50581 tagattacat ggtaagttac tactttcata tagtctgtat ggtacatttc aaggggagaa
    50641 acagtccaca ttagaacttt tagcatatga aaataattgt aatataaatg acattgaagt
    50701 taaacaagtt gttgaaaata tacaatagtc tgcaaattca aaaaggaaac aaaatattaa
    50761 atttaataga ttacataagt tactatcatt gtcgatataa agttatatat taattgataa
    50821 tgatagtaat ttgataaaac aaacatatta ggggaggtat aaaaatgaaa aaaatagcta
    50881 atttgaataa agaggaatta aaaataatat gggagaaaaa tagtcaacta agggaggatg
    50941 taaggaaagc ttgcgaagac aatgacatgt attggataga tgaaatatta tgccatctta
    51001 ataaatcatt agatgattgg tctattggat tttacaatga taattatata aaaatagagg
    51061 ataatcataa atttttatta gaacttaaat ctgtatgtga aaaattttct tttttatcag
    51121 aagaagaaca gagacctctc gagtatgcga tttcattaat tgataaatta cattgtatgg
    51181 attttgaaaa taaaagattt aatatgttgg aaaataaaat taataatatg gtcaaaaaac
    51241 ttgaagaaaa agtaattgaa gaatttaata agatgacaga gccattggac aaagaatatt
    51301 tattagaaaa ttttattgaa ttttatgttg aagcctatct caatgataat gaattttata
    51361 tagataatga gtatgtgtta tacgaaaaaa ttattaaaag ttatgcttaa aagaatgtaa
    51421 ttggagggtt ttaaaatgtt agcaaatcag ataaaaggta ttaaaacatc acttgaaaca
    51481 agcagcttaa gagaactaaa aggatacata aaagatttaa gaaaagcact atcaggatat
    51541 aaatataaga ataaaataga tgaaattaca gaatatcaaa tagataaatt atgttacaaa
    51601 attgataata cagatatatt tgacttgaaa tataaagaaa tagaaaagta tatagatagt
    51661 ttaattttga tacttgattt tatctttatg gaaatgtaat caaaagaatg attttaatat
    51721 aactggaggt ttaagcatga atgagtatat tttgataagt tatacaaaag gcgaaggaac
    51781 ttgtgaccac tgtggaagaa ctataaaaaa tatagctaca ataaaaaata atgttacagg
    51841 agaagttttt catgttggat taacatgtgt agaaaaaata atgaaattga atgttacatt
    51901 ttacaaagca ttgtcgagag agataaaaaa acattacaaa tgcatggagt actacagtaa
    51961 gggtttagat atagagacaa atcttaataa aatagtgaag aataatacta aatacaaaga
    52021 aggttcttat gcttataaat ctaatgaaca aatgttagaa gatgcaattg cagaagtggc
    52081 ttggtctttg gctcgtatga tagatagttg tatgagaatg aataaactta gtaagtctgg
    52141 attgatagat atagatatat tgaacagttt gtttatcaag tataaggaat atatgagtaa
    52201 atttgatgaa aattacaata aaaacaaata taaatataaa agttgttata ctatgaaacc
    52261 tttaaaagta atattagatg aaaatgaaga tttaaaagaa ctatataaaa gtatgcaata
    52321 aatgtatgta ggcgatgaat taatgacaat gaattttata tagatgagga ttatatttta
    52381 tataaaagag tgtcatatct ttaatatagg acatgaagta ataaaagagt ttaaaattat
    52441 atttttaata tgatatatga gttatcaaat cactatcatt atagctatat tattataatt
    52501 taaatgataa tgatagtgat ttgataaaaa ggttttaaag attgtaaaaa tacattaaga
    52561 tgattttcaa acagcttata gaggcttgta cggggtcata attataaact aggaggatat
    52621 aaaaatgaaa ttcaaaaata tagttatggg aatgttatta ggtttaatca ttgtaggagt
    52681 ttcaggagta acaaaagtta aggctgctga attagataat ttttatatag agtccacaga
    52741 tagagttatt gaagttttag aagatgaaag tatagtttta tatgatacta aagagcaagt
    52801 ttataatttc tatccaattt gtatgggaga ctggaactat agctttaaaa ataaaaaaga
    52861 tttagatagc gcagttgcaa cttacaaaga gctatcaagt aatataaatc atttaagtaa
    52921 tatatacgtg gttaataagt taaatgacaa tggaaacatt aaagtatttt taaatgatgg
    52981 aagttcaatt gtttatataa aacaggataa taaatattac ttttatcctt cttgtatggg
    53041 tgactggtac ttaacattgg atagtaaaat ttatttaact aattgtatta atacttatat
    53101 agaatattat tattccttgt caactggagg tggcacaaat gaataataat gataagttat
    53161 ctatattaaa tcaattggaa tacatagaaa atgatattga tgcaagaaat gaaatgattg
    53221 aaaaatttaa ggacttattg gtcaaatatc caaagagtag agatataaga agatatataa
    53281 aacaacaaac tcaattttta aatggtatta gatatatata tgataattta gatattttga
    53341 agaatatgat aaataatgac aagaagtgag aacattacta gacataacaa tgtctactga
    53401 atgtcaaaga gattcattta gtaaatacaa agttattatg tcaattttta attaaattgt
    53461 aatttaacat aaaaatgtag ttactatttt aaaactcata ataactacat ttaataattt
    53521 aaaaagggag atggaaaaag tgaataaatt aaaagttaaa ggaaaacaaa aatttatgaa
    53581 tttagaaata ccagttatag aaggtggttt tggtgaagat aaaaaatgta tgacggataa
    53641 gactatatca gaaatacata atcagcctaa ttttaagata agagagagaa taaaggataa
    53701 tataaaaaga tttaaagaag acatagatta tatagattta aaagttatcc gtgacacgga
    53761 tgacaattta gagctattac aaacacttgg atatagtaaa atgcaaatat caaaagctga
    53821 taatatattt ttattatctg aaagaggata ttcaaaatta attaagataa tggatactga
    53881 tttagcttgg gaaatacacg ataaaataat ggatgaatat tttagtatga gaaaaaagtt
    53941 aaatgaccct tttgaaaact tatctccaga gttaaaagtt ataatcaaac tagaacaaag
    54001 acaagcagaa cttgaatctg gtcaacatga attagaggaa aaagttaatg tcctatatga
    54061 tttttctact atagactaca atcaacaaga aactattaga agtttggtaa atagaatggt
    54121 aatacaagta tatcaatgtt taaatttttc agcttatgaa gatgctaaat taagaaaaag
    54181 agtatacttt tcactatgga aagattatag aaaaaaattt ggtgttaata gctataagaa
    54241 cactgctaaa aagaactatg acaatgcaat taaattcata gaaaactggg agcctaatta
    54301 tgatttaagc aatgaaatat acatgtttca aaaagttgaa aatatataag aataatgatt
    54361 ggagattatt atgatatgtt atgtcaaaga tatacatact ataagcctat atgatgcttt
    54421 tagatggcat acaatggggt tgtcattcat tattaaagat ggtaaattaa aaggttttac
    54481 aatgtaacta attaattgag aagagaatta tgataacatt cttttctcaa ttaattatca
    54541 ttcctaataa ataaagttca aaagatagtg taaaagataa tacattttgt taatattagt
    54601 aatataaaat aaatttaaaa atggagatga atatattgat tgaaaataag tttatagaaa
    54661 aattaaaata taccaaaaac ataccaaact ctttatacaa agacttaaga cataattttt
    54721 tatttcattc aaataaaata gaaggaagta cattcacaag tgaaagttta caagatttaa
    54781 ttgagcacaa cattgtaaaa ggtgaccata ctttagatga tgttataaca acagtaaatt
    54841 caagctatgt atttgaaact gtaatagata cattgggcga atacttaact gaaaagtaca
    54901 taaaggattt acatggacaa cttatgtata attcaaatat tcataatatg gggctatctg
    54961 gtatatacaa aaaaatacca aatagaataa taggaactaa tagtgtatta gcccaaccat
    55021 ttgaagtaga accaaagatg ttagaactta ttgagtggta taataattta aaagatatta
    55081 cattaaaaga cttagcagaa tttcattata gatttgaaat cattcatcct tttcaagatg
    55141 gcaatggaag aataggaaga tttatattac ttaaacaaat acttgagaat aatttgaaat
    55201 tgattataat atcgagtgat actgtagatg attatagaca ggctttaaaa ggttgtcata
    55261 atgaatatta taaaccttta gagcaatatt ttgaaagttt agatgactac aaagaaaaaa
    55321 ataaagattt atggagtttt taacctaata attaaacaaa tgaatggaag tgaaaactat
    55381 gctttacaga acggaagatt taaatacttt tgcaggtatt ggaagttcta aaggtgttta
    55441 ttgtcaactg ccactaccct aaagggtagt agcttgtaaa agctagttga atagcctaag
    55501 tttacactac gttatgtaag aatatatagc tactttagaa tactttaaac ttaaaggaat
    55561 attccacata ttaaaatact ctttttacaa atttataatt aaatcataat ctaacttttt
    55621 atttgaaaaa ctttcaatta accttgcttt atcattagca ttctttaaaa tgtagttatt
    55681 taaccaataa actatcgcat cacccctata atggagtcca atttggactc cattttcata
    55741 acaccaaaaa ggatgctcat cttctgtatt gtcaatccaa atatgaaatt cgtttctaat
    55801 ttcatatttt tttaaactaa tttcattagg aacatatata taatcaggac tatagttgcc
    55861 accaaaattt acttttataa ccataattat agtctccttt ttaaataatt ataacatatt
    55921 ttataaaaaa ctggtaatta cacttgtagt ttaattccaa aatatagcat tctacaagtg
    55981 tatctaaatt tattaaagca aaaatataaa aaaataaagg atactatata tttaaatgca
    56041 ataatttttg tatttaaata taaaaactca tatatttatc tataatatta tatctattaa
    56101 attataaata actaaagcca atatacataa gaataaccac ccaataaagc tttcattctt
    56161 actttcaaac atatttaaaa attttaatgc atctttaaat atcaaaatag atagttttat
    56221 aattacaaaa actgctaata gaataaacaa tgttttaagc atatatttct ccttaataaa
    56281 taatttaaaa tcttatttaa tataaatttt gtttaaatta atctgttatt tataaataaa
    56341 ttatatcaaa gtttgttgca ctttagaaat atatgtaaat aaaaactatt agtcaactgg
    56401 ttaatatggt atgacaacaa taatctcatg tagtatactt aatttagagg tgagtatatg
    56461 acttggaatg atttaaaaaa caatgatata acatatatag ttgaatatat taataataag
    56521 ttaaataata gtaagagttt gactaaagtt gctatagggc ttggtgtgtc tgaaagtagc
    56581 ataagaaaat accttactaa aagaggttat aaacgtataa atgatgagta tgtgtttatt
    56641 ggtgacaata gtatgacaaa agtagtaaac aatagacaac agagtaataa tgataataca
    56701 tttaatatga caatagaaga tgacaacaat cacaacatag taattgacaa ccaatttaaa
    56761 aataatatag tctctttagc aaaagactat gataaaatac aagatgtatt aaattggttt
    56821 gagaataaag aagatacaaa tgtaatagaa gttgtacagg atggtattaa gattgattta
    56881 cattcaaaag atgctataag gactacagtt aggttgaata aagatgcatg gaatttattt
    56941 gatgagtttt gtggaaaatt cagagagttt aataagtctg atttaatgag tatggcttta
    57001 ttagaataca taaagaagta tgataaataa aaatgacaat aaaatcgtag ttttaattta
    57061 aataacctca ttattttgag gttatttttt ttattttcta tttaaaacgg agaaggtaaa
    57121 tgttataata tatatataat taaaaaaagg atgtttgaat ttatgaatta taatttaaaa
    57181 aatgaaaatg tattatcaga gctattacaa aatgaggatg aaaaaacaag gattggtata
    57241 ctcaaagttt ataaagtgtt aatattttgg tttgctaaag aaggaaagct tgttgaggaa
    57301 gaaaatgact atattgttga gatagtaggt aatgataaag aagaaattgt gagagatatg
    57361 agccagaata aaacatacaa tgccataatg gctataattt ttaaaattaa taagatattt
    57421 aaaactttaa attacgatat tcacttttct aaaccaaaaa atttagtcgc tgaatttgat
    57481 ttatcaaaat atctaacaca agatgaagta cttcaggtat gtagtaagct aactaatgca
    57541 caagataagt ttataattta tgcagctttt tgtggtctta ttggtaaaga tgctgaagac
    57601 ctaaggggta taaaaataaa agacatagat ttagaaaaaa gattaataaa gttaaaggat
    57661 acagaattta agctggacaa gttcttattt gattttacaa aagatacatt agaacaaaaa
    57721 gagtataaac aatatttgga gcaagacagc aatgctgctg aattttatct atttaattct
    57781 aattctgaat atttaattaa aactaaacca gatgctagat atggaaatgg attaaaagag
    57841 atgggatact caacaattcg caaaagatta cttattatta atgattattt agataataaa
    57901 gtacagttga atttcaccaa tttaaaaatt tctggtatta tgcatcaaat gcatctaaat
    57961 gaaaaaaaat atactcaatc tggatattgg actaacaaaa gcttgaaaga gtttaaggag
    58021 gataacaatt taaacttcaa aatacaagaa gttctatcta tttataagca aaaatatatt
    58081 aaggagtaac cttatgagta aagatgttaa agaaaacata agtaatgaac aaaaagattt
    58141 aaataaaata aatttaatct atcatattat atatgacaat gatagattta aaatgataac
    58201 aagaaaatat tttgaaattt ttagattaaa gggtatgtct gctgaagaaa taagtttaaa
    58261 atttgaagaa tttctatatt ctcttatttc agataagttt aaaaagataa atacagtaaa
    58321 tgatgttaaa aaattaagaa atcaagagaa ctcatcatca ttaaaactta agaagagatg
    58381 gtctgatatg actttagatt ctctaagtga agatactaaa tcttcaagaa aaaaaagcag
    58441 taaataccta aaaaaagaat tagaaattgt tgaaagtgaa tatttaaaaa atggaagaat
    58501 cattagtgct ggagtaaaaa atccaaaaga attaaaggag caaagaaaag attttttaga
    58561 tgagtggaag tcaagctcta gttataacat atgtgattac ccatatttac aagagttaag
    58621 tactagcaaa ataaattccg catttataca tgatatacta atgtgtataa cagaagtact
    58681 aaaagatgat tatgattttg atattaataa aattgcaatc aaaactccac cacatatttc
    58741 acctggaatt tttttacctt tcacaaaagg taaaagatac tcgcacttga atgttaaaaa
    58801 aaatgaaaat gaatacatgt cagacgacta tagtgctaag aatctttcag gtaaacaaat
    58861 gaattttttc tataagtttt caattgggca agatgaaaat attgaaaatc ttaaactaga
    58921 gctaataaat cctgatacag aaaaaagggc tttgccaaaa atatatttag ataaacaaga
    58981 ccttgaaatt attagatttg tttatactta tagccacatg aactcttttt cattttattt
    59041 aggcgattta gtaaagtact taggactttc agatggaaaa aagaactata ttaatatcaa
    59101 aaatagactc ttaaaattac cttattatac tttttattcg aatcaaacta atgataaagg
    59161 cgaattaaag tatgagatta gttttaattt gttttctagt acaacaatag taaatgatga
    59221 aaacaataat aatagagagt tggttaaaat cacaaaatct tttattgaag aagtcgaaag
    59281 agttaataca gatataatgt atagaaatga acttgaaaaa ttacaattaa cacagtcaat
    59341 taatctagct tatttcttag agggtagaag gtcttttctt atatcttgtg gtgaggatat
    59401 aaaaaataaa agttttagat atgacataga agatttaaaa tttgatgttc atcttaataa
    59461 aagtaaaaca gtaaagcaaa atatggagta tttagaacta ggttttaatg agataaaaga
    59521 aaatcaattt ataattaaag actataaaag aggaaattct tattttgatg tttatttcta
    59581 tgaagatttt gaaaaaagaa aacgtcttat aaataatact atactttctt tacctgacta
    59641 catgatagaa aataaatctt aaaaatggcc atatattctc cgtacttaac aaaaaatgtc
    59701 gaatttattt taaataaact taataaaaaa agtaaaatga ccgtatattc tccgtactta
    59761 acaaaaaata gatttttcaa aaaaactaaa tgaccgtata tcttccgtac ttaacaaaaa
    59821 atagaccttt ttttaattat ttccttgtcg aaaaattttt tttgtaacat attttttact
    59881 tttcttagta atttcaaatc tcacgtcttc tgaaatcact atgtctgagc taaatgaccg
    59941 tatcagctcc gtacttaaca gaagacgttg aaaccactct atttgagcta aatgaccgta
    60001 tcagctccgt acttaacaaa tatagacata aatttatttt ttgggtaaga taaatttgag
    60061 taaaaggaat catcaccaaa atggctatat cagctccgta cttctgaaat tattgatttt
    60121 tcaaaggaga aaattatgag tcttaaatat aaagataaag aatttgtact tgtagaaaaa
    60181 aagaatataa atgaattaga taactctaat ataaaatata ttgacctaaa ggacaagcag
    60241 tattatgtgg ttacacaagg caaaaaacct aaaagattta acctagaaga tattaaaaat
    60301 ataaaaaaag atttagataa tggcataagt ttaagaaagt gtgcaacaaa atggaactgt
    60361 agcactagga ctatacagga tataaaaaat aatatttatt aatatacaga ggtatttatt
    60421 tactttatac ctcattaaga ttataataat catatataga gaaaggagga ttataaaatg
    60481 caagaattaa aaccagttgc tagaatatca aagtcaaaac taaaagatat attagatgtt
    60541 tttaaaactt ctataagaaa agtagaaaaa atagattatt ctgcttgtaa ttcttgtgca
    60601 ataaaaaata atccttcttt tgatagtcat aaattaaatg aattttgttc aaattgtcct
    60661 aaattaaaaa ctatatcaga gttttcttat gttacagaaa aggaaacaga actaggtaca
    60721 atagaaattg taactaatga aagtaaatgt atggctttaa gtaaaagtgc tataaaacag
    60781 tatttagcat atcattttat agtatctaat aaaaattatg ttagaaaagc agtatccttc
    60841 caaaatatag ccgatatatg caatgtttcc attgttacag ccagacataa ccataatgta
    60901 ttactacgag ttggattagt ttattctaca gaaataaaaa gaggtaaatt tgatatagtc
    60961 atagatgaag agtacaaaaa ccatcttaaa aaagaagatg gtggaaaagg ttacttaact
    61021 atgtcattag atactttaaa tcacttatta agttttgaaa atgtaaatga gttaaaactt
    61081 gaaattaaaa aattaatttg ggctgatgct aaaggaagta agttaggtaa aagaatacga
    61141 tttaaaaaag acaatcttat ttctatactt ccagaataca taaagaaatc aaacaagcgt
    61201 acagaagcct ttttaagaag ttctaaaact ttatttgatg taagtaatga cacaatagat
    61261 acaaagcgtt atgagacgaa agaaactatc tcagagaaat atacagaacc aattagaata
    61321 caaatatcga aattctttga taatactggt tgttctttga gttctaatta tagtaaagtg
    61381 ttatctcaga taaatttaga tagatataat ttatttgaag aagatttaag aagtaaatta
    61441 gacatggaaa aagatattat tataaatgac ttagttggat tgtcggtgca gtatggagtt
    61501 actagagttt tagcagcatt agattatatg tttaataaat atacatttga tgaagaagat
    61561 ataaattata atgaaatacg taatcctggt gcatttataa gaacattgat tgttcagagc
    61621 ataaataaaa atggaagttt agcaatagca atttaatata tggagtagtt caaaaaaatg
    61681 attttggcta ctcctattag tgtttgtatt caaattataa aatacttaaa tagagctata
    61741 aagagcgtga aatctctatt agctctattt ttttatgcct attttaatga aattatatac
    61801 acaatagaaa gttttttata catattacta atttaatttt acaataataa tatatattta
    61861 ttcaatttat taagaaactt attaaaaaaa aatactaata catcaacaag atgttaatat
    61921 tgaaatttat attttatttt attccttaca atcacttcga tttatagttt tttctgactt
    61981 tctaattatt ggttttaatt attactttta atttttgttt taaattctga aaaacattta
    62041 ttatttatac tttaataaat taaaagataa ataatatcga atatatgttc ttgaaatatc
    62101 gaacaaaaag agttataata ataatgtgct aaaaataatt ggtatatatc ttgcacacat
    62161 aacaagaaca tatgtttgca aaacggttaa ttgtttatat ttctatctat tttttatgtc
    62221 ttatactata aagttaaata taaaattaag ataaatatta ttaataataa atagtttgaa
    62281 aattacaaaa atatgtcgat agctggtaaa aaatggaaga actacttgga tagaatgtat
    62341 gttacaatgt aattaattaa gtgtaaaggg gaagtattta taataggtat actttatttt
    62401 tctaaggggg aaagtttatg tcagaaggaa aaattaacaa agaaaaatta atgaagctag
    62461 gtaatatgct gtcagaatta aaaaggaata ataaagataa atttacaaat tataaatctg
    62521 aagttgagaa atatgaaaat aaaaaaagag gagcataaca tcctcttttt acttcttatt
    62581 ttcttcctct aaaaaaacct cagctacatt gtataatctt ttttgtgctt ctggacttaa
    62641 tttacttatc attcttaaca tttctttaat atcatcatca aaatccatat ctaaagttgg
    62701 gtcttgaaat atatcccctt ctcctgttct taaccaattt tcgtttacat taaattcttt
    62761 gcatatatca ttgattattc tatctgttaa atctctccta cctgtttcta gtgaggaaat
    62821 gtggtcttga gatagaaata atttatttcc catctgtgtt tgattcagcc ctaattcttt
    62881 tcttaaagtt ttcaatcttt tattcaatat tatcacctcc ctctttaaaa tatattatca
    62941 tataaaatat gtctttgcaa taaaattgat ataaaatatg tcaaaaacat attacctgtt
    63001 gacaatatgc taatgacata atataattta aatatggaat gtcaaagaca taaaaaggag
    63061 tgataatatt tgcataaaaa aaagatgaat caaaaagagc ttgagttatt agggaaaatg
    63121 tttttaaaaa taaaaaaaat agataaacaa aaatttggag agttaaaagg ttctgttaaa
    63181 acatcgcttg aatatgaata tattttagtt aataaaatta gataagtata catacgtaca
    63241 ttgaaaactg aatattcaca caaataaaaa gtgcaaccat aaattaacaa attttataat
    63301 cgcacttctt catttattta aaacatggat atacttagtt tcttttttat aaaagagtag
    63361 cttagctact cttttataaa ttatttttta gaattcagta acttattttg agttttaagc
    63421 aactcttttg ccattaataa aaggtattct tttgtatcag aagttaaaga atcaaaaatg
    63481 ttaagaaatt ctttttcgta tggagaggaa gcaaacatat ctccctctcc tgttcttaac
    63541 caattttcac tgacaccaaa ttcagaacaa attaatttta tatgtttgtc actgaaagtt
    63601 cttttattaa cttctatcat tgctaatgtt gattgactta agcctatctt ttttgcaaat
    63661 tctgcttgat taagtttcaa tttttctctg atttgtttta ctctagtata cacatgtttg
    63721 cccctttcac ttattttgta attaaataat atcacaataa tattacaaat gcaattaaaa
    63781 tataaaaaat aatattacaa ataaaatata aaagtattga ctttaacttc atttgtaatt
    63841 ataattaaat tacaaatgaa gttgagaggt gatgtaatgg aagatataat cacaactgaa
    63901 atgaagaata catttttaaa tttatcagta aataatcaat tagaaattct taatcttgct
    63961 aagactatta aaaaaataga agatgcttta aatattgaag acaatgagaa ttataattaa
    64021 aaaatgaaat gattaaggag aggatttgaa ttgaataatt taagaatcaa gggaaaacaa
    64081 aaatttatag atttagaaat tcctattata gaaggaggat ttggagaaag taaaaaatgt
    64141 atgacagaca aagctatatc tgaaatacat aatatgagaa atgctgatat aagaaggaga
    64201 atatctgata atttaaaaag gtttaaaaat aatattgatt atatagattt gaaacgtgtg
    64261 catgagacgc acacgttgat agaattaggt tattccaagc aatctataac tcaagctgat
    64321 aatatatttt tattatctga aagaggttac tcaaaactaa ttaagataat ggatactgat
    64381 ttagcttggg aaatacacga taaaataatg gatgaatatt tcaatatgag agaacagctt
    64441 acagatagtt atatgattca agattctatt gaaagagcta aaagatggat agaagaagaa
    64501 aaagaaagat tattacttaa agaaacaatt caagttcaac aacctaaagt agaatatcat
    64561 gataaagtat taaatcctga caaattagtt acgacaacag atattgcgaa agatttagga
    64621 atgacagcac aagcattaaa taaattacta catttaaaca gaattatata tccagaaaga
    64681 ataaatgggc gaataaaatg ttggaaacca tataaaaatt atttatggtt gatacctgaa
    64741 tatgcagatt ttaaaataac agaacatgat acgcagctta aatggactga gataggtaga
    64801 aaatggttaa tagaatttgt agagaacatt aaaaaaataa gttaaatcaa gaagttaaaa
    64861 tgtaccttga aaagtagata tttaaaaata taaaagatag gtgattaaat gataaaacaa
    64921 atactaaata aaagaggtag tctattaaat ctagcaagtg agtatttgac agaacaagac
    64981 tacctcaagt ttcaaggatg gtatacacat agatatagta agatggatgc ttatgacgct
    65041 tctataaatg aatatttaaa ttataaaaac gacaaaaaat taataacgta tgtatttaat
    65101 ttaaaatttc aagaagctct catagaaata taatattact aaacatggtg attgaaatga
    65161 attataatta tgtaactaaa attgacttga aatatggaaa tacacaattt gggtttgaga
    65221 aatatagcga tgctttagat aagtacagag aacttaaaga agaatttaag tatgttccat
    65281 gtattataaa acttcattca tatgtagcgc accaagattt atatgtgaaa gaaattaaag
    65341 ctgatggttt tgaaaagaaa tatttagata ttaaaaattt aataaaattg tttaaagaac
    65401 ataaacaaaa tatatcagat gaactaagtc tttgtgataa gaaaaaggaa gaagtattac
    65461 atgtaataga agaaatgaat ttagacacag cttctttaaa tgataagatt gataccatta
    65521 aagaattaaa aaacacttta gctaagagaa ggttggttaa atatgaacta aataaatact
    65581 ttgccttttg taatacatta tatgaaattg aagaagagtt aaaaaaatat gaatctaaat
    65641 ataaacaaaa agaaaatcaa ggaaaaagca gattcaaaaa aaataaaaaa taggtgatta
    65701 gatggaagaa tattatttta acttaataaa aaagctttgt gctgaaagaa aaatacacaa
    65761 aggttggttt agaaatattg aaaaatgtgg ttgtggaggt aaatgtaata agaaaaattg
    65821 taagatgtta gaaaaattat aaggagatac atatggaaaa tcaaattgaa ttaacagaaa
    65881 aagatataga aaacacttta agtgctttaa atattattaa atatatttgt ataaaatcta
    65941 aacattgcaa aaattgtcct cttggatata tgaaaaatct tgatgaacat aattgtatgc
    66001 tatatgaatt aatagacaag ggtttacttc catgtgattg gtctgtaaaa aaagttacaa
    66061 gattgttaga tacgacagaa gaataaaaca aaggagctgg ttaagtggag ttagatttca
    66121 gaatttggaa tggatttaga atgatacatg gagaagaatt aagattacta acagaagaga
    66181 tgtttataaa aagtggatat tctgaacaat actataacga tatttgtata ccaagagtag
    66241 aagatttgaa aataatgcaa tacatagggc taaaagattg ttttgaaaaa aagatatttc
    66301 aatatgatat tgttaaattt atctttgatg gtgtttggaa agtatgttta gtaaatttat
    66361 ctttgccaaa aaggagcaac agttacattt gaaagcatag gtggaaaata tacttttaat
    66421 ttaagtgaaa cattttcaaa agataggaaa ttagaaatca taggtaattt ttatgaaaat
    66481 aaagatgtaa tcaaaaaata taatcttagt attgaatagg agaagaaaat ggatgaaatg
    66541 ataattaggg tgaaaatggg agaaccatta ccaacactag gaaagataat caaatgtact
    66601 acatgtttaa ctaatgaaga gaaatgtttt aaggttaata agatatgtaa attaagttgg
    66661 attaacgata ggaatagtga agggttaatt gtagaatgca aaggtaaata tattaaatat
    66721 taataagaat aatgaagtta aaatcaagat tttaatagaa aaggagtgat taaaaatgaa
    66781 gaaaaatcca ataaaaatta aaaaatgtga ctgtggtgga gatatatatg aacttaatac
    66841 acaattaggc actatgtatc aatgtaaaag ttgtggcgag atgtatagat agtgctgaaa
    66901 tattagctaa agaagatgag gtgaagtcaa tgagtaaaaa agataagtta tctattttta
    66961 taagtttaat attaagacat aaaccagaaa ctattggaat taaattagat gactatggat
    67021 atgcagatgt taatgaattg attgaaaaaa taaataatac tggtagaaat attaatatag
    67081 aaatccttga gcaaatagtt aaagaagata ataagcagag gtacagtttt aatgatgata
    67141 gaagcaagat tagagcaaat caaggacatt caattaatgt tgaggttgaa ttgaaagaat
    67201 tagaaccgcc aaaatgtctt tatcatggaa cggctactag atttttagag aatattaaaa
    67261 aggaaggtat tattagacaa agtagactgt atgtacactt atcaaatgat atagatacgg
    67321 ctgttaaggt tgggaaaagg catggtgtac ctgtagtttt aaaaattaat acaggaaaaa
    67381 tgtatgaaaa tggttataaa ttttatttat ctgaaaataa tatttggtta tgtaagtata
    67441 taccatttga atatgtagag aaaataagta gagtagttaa ataaaattat agaaaatagg
    67501 aggttattga atggatttca attttagaaa gatttgtgaa aaagatgaac ttactgatga
    67561 ttttattata aaaatttgcc agttgtcaca tgaggagttt ggaggcacta tttatgtacc
    67621 atgtaatatt catccatgtg ggtgggatga gttggaagtt ccgaatccaa aggatttaga
    67681 ttcagataaa ttaatggaag aatttttatt agaatataaa tttgaatgtg aaaatatttc
    67741 gagcaatatt tatgatagtg accatccatt tataggcaaa acattgagag agattcttat
    67801 gatagtggat tgtagattca taattggtgt tatataagga gggtattaaa tatggaaaat
    67861 atagaattaa cacctagaga ttattttgag gatataaaaa ataaaaagca aaaaaataca
    67921 aatgaaaatc ttgatatagt atatgaaaac tctttgattc ttttaaacaa atatattgta
    67981 actggtcaaa aaaagggtgc taagaaatta atgtttttac ttgaatgtat tgaaaaagaa
    68041 agaaatgtaa tagagctggg aatagataca tttgtgtata aagaagatat agaaaaatat
    68101 attgatgata tatctaaaaa tacagtaaaa ataatagaac ttgaaaatta tgaaagagaa
    68161 ataccagatg aaatagtaga aataatagaa aaaacaaaag atatatttga taaaatgtat
    68221 gttttgttta ctgattatac aggtaaaatt acaaaggaga taagcaaaga gagaagagat
    68281 aaagacccaa tattatttgg tgttttttca gatgagaaaa gcagagctat tgtagataga
    68341 ttttattatc ttggagattg ggaggatgag tattgtgatt taacattaga gaaaatgata
    68401 aatgattata agaaaaaagg aagacaagac atattaaaac atataattac acctaaatca
    68461 ttagatgagt taaaaaaaga attagattct ttagaaaaaa ataatgatac atataagcaa
    68521 gttgccaata taaagccatt acctactaca aaaaactcta gtgtagaacc acctaaatta
    68581 aatatattta aaaaaataaa aaatagagtg tttaaaaatg aaaagtaatg ttgatttaac
    68641 agagaatagg gattttagag atgtaagagg aagaggcatc aatattttag gtatcgaaga
    68701 tgcgccaaat agaatgttga gttttagtga ttttggaatt ggacgtcttt atggtaaaaa
    68761 tttagaattt gaatttaata aaaatgaagt atttttaact ggaaatgcta atgacagaga
    68821 agaaaaaaag tttcttatcc tttgtgaaga aaataaggtt tgtgttagat gtggtgatga
    68881 attaagagag gggtgggata aagtaagcat agaactatgt aatgaatgtt atgaaatgtt
    68941 agatgttgag tataaaaata aaaagataat tagagaatta ttttttagag atagagatgt
    69001 aaatatagag ttactttaaa aaatatataa gaaaaataag tagaggagga atttatatga
    69061 aagatgtttg attatatagc tgggatgatg agtgctttgg aagtgatgaa tacgaaagta
    69121 gagaggaagc tattcaagga gctaataaaa ctagtatttt tagtgatgac aacagtatga
    69181 caagaataat gagaatataa aggagtgatg tttattaaaa gttttagatg tatattcaga
    69241 cataagtttt caaggataaa agattgtcaa ttaattacaa caaggagtca gcaatatacc
    69301 tgtaaaattt ggatgtgtaa atattgtgga caaattgtag ctggttcaac tcctgtttat
    69361 catcctaata tgaaagtcaa tgagtattgt gtaaagtgtg agttttcggc atgtgcaaat
    69421 aattatgagg gatattgtaa ctctaaagat aaagaaattg aatttaagtc tatttgctta
    69481 aaaggtaata aagagatttt gcagtgtaaa aattttgatt tggaataaaa tttagcttaa
    69541 gtaggagaat tttagaatat gaaaataaat gtacatgtta aaactaataa aattggttca
    69601 gactgtgagc tggagtttga aatagatgat gatgatttaa aagatatgtc tgatgaagag
    69661 agagaggatt atatagataa aatcgcatgg gattatgttt ttgaaaattt tatagattgg
    69721 aattggtatg aggtcgaaga ttaagttaaa acaatagttt taattattta taaaggagga
    69781 tttaatgtga ataaagataa tttagaaaca attatagaag gttataaggt atttaatcca
    69841 gattggactt gcagaaattt taaatatgaa gtaggtaaga cttatgaaca tgatggagat
    69901 atagaagtat gtgaagctgg atttcatttc tgtcaaaaag caattgactg ttttaactat
    69961 tattcttttg ataataaaaa taaagttgct aaaattgaag caatagggtt aattaagact
    70021 gatggtgata aatctgtcac aaataaaatt acaatagtga aagaaattga gtgggaagaa
    70081 ttattaaata ttgtaaatat agggaataac aatacaggat atggtaatac aggaaatcat
    70141 aatacgggaa atcataatac aggaaatcat aatacaggat atcgtaatac aggagattat
    70201 aatacaggaa atggtaatac aggatatcgt aatacaggag attgtaatac aggatatcgt
    70261 aatgaaggaa attataacgc aggaaattat aacgcaggat attgtaatac aggatattgt
    70321 aatgaaggaa attacaatac aggaaattat aactcaggga attgtaactc aggagattgg
    70381 aacataggag attataattc aggggtattt tgtacagatg ttccaaaaat caggatgttt
    70441 aataaagaaa ctgatttaac atatgaggat tggatgaata gtgatgcacg aaatatttta
    70501 aaaagaaata gttatttaac aaaatggatt cacattgatg acatgacaga agaagaaaaa
    70561 gaaaataatc caggatatga aattaataat ggttatttaa aggtgtttat atttgaggag
    70621 atgtgcaaga acatgtggga tagcttaact gaggaagaaa agaaaattat tatagaaata
    70681 ccaaattttg atgctgatat ttttaaagag ataaccggaa tagaagtaat ttaaattaaa
    70741 aataaaggaa tgcaacatag tggataaaca agaatataca aattgttgtg gtaattgtaa
    70801 agaatgtgat gaatatcata agatgttatg taattcatta tatgaggagg aataagaatg
    70861 gctaaatatg atttattgct aaaattaaat aatattttat tcaagatgga aaaacattgc
    70921 gatgaaatga ttaaaaataa taacgataag gaattgagaa cctgtactaa ttgcgaattt
    70981 gcttattatg gtagttatgt tgaaagtgga tgtgtttgta cagatattga aggatttggc
    71041 atacatgata tggtaaaaag aattattgaa aaaaataaag aaaagattga tttagaaaga
    71101 aaaataaagt atccagctat atataaacat tttaaaggcg gattttatac agttatggga
    71161 attagtaagg ctgttactgg tgatgaactt gataatatat ttaaaaatat gggatgcata
    71221 aacagactgg atgtacttga atatagattt ggttctaggc atacagaaac taggcataca
    71281 gaaactaggg aaaatgtaat tatatacaga gacaataaag gcaatttata tcattataaa
    71341 gatgttgaca ataatacaaa tttagtaata tataaaactt tatatgatgg aactggagct
    71401 tatgcaagac ctattgaaat gtttttttct aaaattgata aagaaaaata tcctaattat
    71461 actcaaaaat acagatttga agaggtgtaa atgtgccaac atttaataga tatagaatag
    71521 aagatttaag tggattgcaa aatgaaaggt ggagaagtga agactccaga aatatatgct
    71581 tagctgattg gattcctgga aacatctcac acaattccaa tcctacaatt gttgaccaat
    71641 ttaatgatga acttggaggt ctagcaaatg aatttacaca atggaatatg ggagattttt
    71701 ttgctcaatt tactccaata aaaaaagtta aaataggaga tgtggcaaga aaatatttga
    71761 atccgcatta ttatattcct gatgaattta attttaataa tattacaaat gatgagagtc
    71821 tatatttggg aatagaatta gaagtagata atggtggtaa aagtgaagaa aatgcaaagt
    71881 ttattcagga atttttagga gaaaagaatt gctatattgt tggtgatgga agtttacttg
    71941 atggcttaga aatagtaact catccttgta ccctacaata tcataaaaaa ttagaatata
    72001 aagatttatt tgaagaatta aaagaaaagg gatataaatc tcatgataca tcaacttgtg
    72061 gttatcatat acacattaat agagattttt ttagcagtga tttaactata caagacttat
    72121 gtattacaaa gattttatat ttaatagaaa aatattggaa atatgtaaca gtaatagcta
    72181 gaagaaggtc aaaccaatat tctaaaagat ttggaattaa agataatgaa agtatgtttg
    72241 aacttttaat taaagcaaag gggagttacg tatctaaata caatgtggtt aatttacaac
    72301 atagtaaaac aatagagttt aggatgttta gaggaacatt aaaatatgaa acttttatag
    72361 caactatgga atttgtacat aatttagctt atatatgtaa agatacatct ttagaagata
    72421 tacaaaatat agaatttcaa gatatattaa atgtatatca aacagaatat ctattgttat
    72481 attttaataa tagaattgaa aatatgaata atactgttga tttagaagat gaatataaag
    72541 aaaatcttag aaggagaatt tttattagag atgaatggtc actttttcat gagagcttaa
    72601 tgtaataaat ataaattata agatactaaa tagctcataa tacgtgactt actatataag
    72661 gaggtataat tttggacatt aaatcaaggt tagaatcaaa agaatataat tttcttagag
    72721 aagaagaaag attaaaaaat agaatgatac ttcctccaat tgtaagaagt tttgcatatg
    72781 gaactaatat agatactcct gagcatatat ctgatttaga cataagaggg atatatttaa
    72841 attcagtaca agaaatatta actatgaatt gtataaataa gccatatgaa aataaacaaa
    72901 cagatacagt tatatatcca ttaaagcaaa taataacatt attattaaat gtgaatccaa
    72961 atgtaataga aatattaggt acgagaaaag aagacttatt tgtttgcact gaagaaggga
    73021 agcttttaaa agataatgta gatttatttt taactaaaag agctgctaat agttttggtg
    73081 gatatgcaat atctcaacta agaagattac aaaatgcttt agcaagagat aattatgaac
    73141 aaaaagaaaa agaagaacac ataatgaaca gtgtaaaaag gcaaatgaaa acatttgaag
    73201 atagatataa agtcgtatct gaggaagaaa taaaattgta tattgaagaa tctaaaagaa
    73261 cagatttaga agaagaaatt tttatagatg ttaatctgag aaagtatcca cttagagatt
    73321 taaaaggtat gtggagtgaa atgaataata tactaaaaga ttattctaaa ttaaatcata
    73381 gaaataataa aaaagatgaa ttacacctta ataaacatgc tatgcattta attagattat
    73441 ttttaatggg tatagaaata ctagaaggaa aagggattaa tacatataga gagaatgata
    73501 aggagttttt attagatata agaaagggaa aatataccta taatgaaata tttgagatgg
    73561 taaatgaatt agataaaaac tttaagtatg cagaaaaaaa ttcttgtcta cctaattctc
    73621 cagatatgaa aaaagtaaat gaactggtca tgtatatgac taatagagta ttaaacagat
    73681 agataatcaa agaggtataa acatgagcgt aatcaataaa aaaaataaag acattcattt
    73741 ttatgaagag aaaatatcta ttcctaatga gctatagatt tattttaata agtggttgga
    73801 aactagcaaa atcaaataag gaggtattag tttgaatata aataaattaa aaaaaataaa
    73861 agaaaggaaa acaaaaagat ggaatataga aaaaattact aataggataa atgaccatat
    73921 gaatattcag gaggatatag aaaaatggga taaatttgaa acaccaatta ttagtaagga
    73981 ggtagatttt tatttattga aaataggatt tcaatatgga aggaataatg ggaggaatgt
    74041 cttggtagga attaaggata tgcgtcatat atcaataagt aaagttaatt ctaacttatt
    74101 atcaatagat atatataaat ttattaaaca agaagatggc aaatttagtg aatttaaagc
    74161 acatgaatat atagaaaagt aattaaaaca tttgttttaa tgtgatttta cctagtagat
    74221 acaaggaggt ttttaatgaa agagctttta gaagtaaaaa aaatatttga tagtttagca
    74281 tctacatcta gtagaaaaga aaaagagaga atattagaaa aatataaaaa taatagaatg
    74341 tttgttgaat gtttacaatt tctactagat tcaaatattc tcactggaat atctaagaat
    74401 aaaatatgta agaatttaaa taatactggt cataatgaat tagagaacat atatgatatg
    74461 cttgactatt taattaagaa taatactggc agaaatatag atgtaaaaac aatacaagta
    74521 tttgccagta aagatgaaaa attaaaagat tttattttta atttagctac aaaatcaatt
    74581 aaattaggaa taacatataa gactgtagac aaaataatgc caggtttaat tatctaataa
    74641 attttgtatt ttttacaaaa aactattgag aacatagagg ttatatgata taataaaaat
    74701 atattgagaa cagagaagtt aaagaggggc aatgagatga ctgacaaaat aataatagca
    74761 agtgtagatg gagaggaaat gatatttaga actgaaatga aaaagttaga aaaaggagat
    74821 agtcttatag tttctgtaaa tggtgtaaaa agattagctc tattcattag gtatataagt
    74881 acttgtgaag aatatataga agatatagca tttcaaaaag tagatgaaat attatatgaa
    74941 aacacaattg ccaaagaaaa agaaagagtt aaaaaggtat ttaaagataa gtgtatgaaa
    75001 aattataaac ctattgttaa tacagaaata gactcttatt tgagagaatg tggtttcaat
    75061 tgtgatggta gacaattttt caaaagtata gacaatacac aaattttaat tagcagggat
    75121 tgtgataaag atgttttgac tgtatcgaaa ggtttgacaa taactaaaac agatataaca
    75181 aataaaaatt taattacagt tattaaaata ataaataata gtctattaat agttaggtaa
    75241 tagaaataaa tattgaactt ttaataagaa aaaagatttt aaataaaagg agtgatttaa
    75301 tgaagaatgt tattaaaaga gatgggagga tagttccctt tgatgaaaag aaaataataa
    75361 atgcaataga aaaaagcttt ttatcattaa ggaacaaagg aaaaagtgaa gtatttgata
    75421 gagaattagc aacactaata gctaaaaaaa taaaaaataa accatgtgaa aaaatgcata
    75481 tagaagatat acaagatata atcgaattta gcttaatggc tagtaaaaag aaagatgtcg
    75541 ctaaagaata tataacatac agagagaaaa gaaatatagc aagaggaaga aaaacttata
    75601 atgattatat gtctattgta aatactgaaa gtaatgatat aactaaagaa aatgcaaata
    75661 tgaacgcaga tactccagca ggtatgatga tgaagtttgc aagtgaagct actaaaactt
    75721 ttactgacca tgtactttta tctgaagaag caaaagaagc aatgatggat aattatatac
    75781 atatacatga taaagactat tatcctacga aatcattgac ttgtatccaa catcctttag
    75841 ataaaatttt taataatggt tttagagcgg gacatggctc tagtagacct actaaaagaa
    75901 tagagacttc aagtatatta ggatgtatta gtttagagac tgtacaaaat gaaatgcatg
    75961 gaggacaggc gataccagct tttgattttt ataatgctcc gagtgtaaga aaaacattta
    76021 tagaagaaat aaaaaatata gaaataaagg atgatattga tttatctcat ttatacaata
    76081 tagaaataga ggattatata attaaggact taaaagaatt agacagcgaa aaaagaaatg
    76141 ttcaacatgc tataaacaga actgtatgga gagttcatca atcaatggag tcatttatac
    76201 ataatatgaa cacaattcat tcaaggggtg gaaatcaggt cgtgtttagt tctataaatt
    76261 atggtacaga tacttcagca gaaggtagat gtataataag agaaatacta aaatctactt
    76321 atgaaggagt cggaaatgga gaaacaccaa ttttcccaat tcaaatctgg aaagtgaaag
    76381 aaggtgtgaa ctataatcct actgatagaa attatgactt atatgaatta gcatgtaaag
    76441 tatcagctaa aagatttttt cctaattttt taaatttaga tgcaaccttc aataagcatg
    76501 taaaatggaa aatgtgcgac ccaaacagat atatttatga agtagcaaca atggggtgtc
    76561 gtacaagggt atttgaagat ttgcatggag aaaaaacaag tataggaaga ggaaatctat
    76621 cttttacgac tcttaattta gtaaaaatgg cattagaggc taaagaaaaa tatccaaata
    76681 atgaagctaa tagagttgca gagtttattt ttcttcttga taaatattca gatgtagtag
    76741 caagacaatt atatgataga tacttatttc aatgtactgc taaagcaaaa cagtttccac
    76801 tattaatgag tgggttatgg aaaaactcag aaaatttaaa tccaaatgat gatgtaagcg
    76861 aagttttaaa gcatggaaca cttggggtag gatttatagg tctagcagaa tgtttaatag
    76921 ctcttatagg tgagcatcat ggtgaaagcg aaaaggcaca aaaattaggt ttagaaatca
    76981 tatcacttct aaagtctaaa gtagaaaaat ataaaaagaa atataacctc aattattctg
    77041 tattaggcac acccgcagaa ggtctttctg gaaaatttac tcaaaaagat aaaaaaatat
    77101 ttggagaaat aaaaaatatt acagacaaag attattatac taatagttct catgttccag
    77161 tttggtataa ctgcaatgtt gaacataaag cgaaaataga agcaccttac catgaattag
    77221 aaggtggtgg ccacatattt tatgttgaat tagatgggga tgcaacacat aatcctaaag
    77281 ctataatgaa agttgtggat ttaatgaaaa agtacaatat gggatatggt tctgtaaatc
    77341 atacaagaag tagatgtatg aattgtggtt ttgaaaacgc agattcagag ttaaaagaat
    77401 gtcctaaatg tggcagcaat agtataaata ttatccaaag aattacaggt tatttagttg
    77461 gaactacgga tagctggaat aatgcaaaat tagctgagtt aaaggataga gtcacacatg
    77521 gataaagact atatttatat tttagatata aaacatgaca caattgttga tggagaaggg
    77581 tttagaacat ctatttattg ttctggatgt aatcatatgt gtagaggctg ccacaatcct
    77641 caatcttggg atataaaaaa tggaacttta actaaagtat tagatattta taaggaaatc
    77701 atttcaaata aattttcaga tgtaacattt tcaggaggag acccacttct acaactgcaa
    77761 ggatttgttc atttagctaa attaattaaa aagaatacaa acaaaacaat atggtgttat
    77821 acaggtttta agtttgagga actcataaca gacaatgaaa agctagaatt gttaaaatta
    77881 atagatgttc ttgtggatgg aaaatttgaa gaagataaaa aatctttaga gttgattttt
    77941 aaaggttcgt caaatcaaag gataattgat gttcaaaaaa cattgtatga aaaacaaata
    78001 gtattatatg aataagagag gcttagccct ctctttggag gtaaatgtta tgaccaaaga
    78061 agaatttatt actaaatttc ttaaagagca gcagagaaga ataaaggttt tatattatga
    78121 agttgaaaat ttcaagatgg atagaaggtt taatgagagg aaaaagtcta ggagacatta
    78181 aaatgtttct tttaatataa ggaggaagta gctatatgta ttttgaaacg gacattataa
    78241 aaaataagaa tactgtaaat aaaataataa aatattgtgg tggaaatact gaaaaattga
    78301 aagattggct aaaagaaata gaaaataaaa gtatcagtag tttagaagaa ttaaaagaat
    78361 atccattaaa aagaaattat aaatttgtat tttccaaaga agaagctcct aatttagata
    78421 agcttataaa aatgaaacta agagataatt gtttagaaaa atgtgagatt tgtagtttag
    78481 aaaatctctt aagtatgcta aatgatgaga ttttagattt aaataaagaa gatatctctt
    78541 atgaagataa tattgaatgg attgaaaatt gtaaagaaga actaattaaa ttaaaggtag
    78601 gaagtatttg catagattgg tagaaaaata aaggagtgat actgtgagat tttggtgtga
    78661 gaattgtaat aaatacttca atgcggaaga aacattacaa gaatataatt atttcttaaa
    78721 tgaagatata atagtatgtc ctagttgcaa aaaagattta atacctatag ctagggaaac
    78781 agaattatca ttaggttttg atagtgatac aaaccaatta acttatgttg aatatgattc
    78841 tagtgattat agtttactta gaaaggtaaa tgcagatgtt gaagatgtag taaaacctat
    78901 aatacattac ataagaaatt taaataaaaa tagtttagat ttaaatggaa ttacaataac
    78961 aatgaatggt aatagagaag gaaaaagact tgatggatta aattatgaag aaggagtggt
    79021 tatggataat ttgataaatg catggaatgg attttgcaaa ttaaaaagac agcatccttc
    79081 tgagctagga gattttcaaa atgctataca tcaagctcaa caagtattag ggttaagagt
    79141 tttaagaaat gattatccaa aaggttggat taaaaaataa atataataag gagagaaacc
    79201 atgtctacaa aaactatatt aaaaaatata gatataaaag atgataaagc agcagaaaga
    79261 ctaatatcgg ctttggaaga atcagaaaat aaacaagatt cagattggga tattaaaaaa
    79321 atgttggaac taatagacaa tcttccttgc cctcatatta tatatggaac tccaaaagca
    79381 ttaagtaaat tagaaaatat tttaaatatc ttaaaaatag acaaagcaaa ttctcatcat
    79441 gttcaaaatt ttatagaagt accagtaaga gatttaagtg aatattgtaa ttatgaaaat
    79501 aataaatctc tctttgatga tagtgtgctg tacattgtac caagaggtac aaagttaaaa
    79561 gtatatgggg gagaatatag gcatgttact ttgaaataga tgaggatata tgtgtatcaa
    79621 aaggaggttt gaatgaccaa atataaaata gaagatagaa ctaatcttat aattcatcaa
    79681 tctaaaaaat ataatgttaa gtttatctta attccagaaa atgaagataa aagagaaatg
    79741 cttaaaaaag ttttaagatg cttaaagaag gaacgtattg tgtttctatt gaaggtaagt
    79801 taagcagtga ggaagtagaa ttaggaaatg ttacaataac aatgtttgta gatggaaata
    79861 ttattttaaa aatggatgtg ttgaaatatc tggtgagtat aaagttgaat agataaataa
    79921 aattagaggg gagaatgaat atggaattta ataattttaa aaaacaagtt caagagagat
    79981 ttaataaaat gacaactgga atctcttata tatatgaagt agatttagat aaagataggc
    80041 tgtggaattt atatttagat agttttccag aaggtacaaa cgaaatattt agagagagaa
    80101 gagaatatga ttgctcttgt tgtaggcaat ttattaaaaa tataggaaat gtagtaacta
    80161 taaaggataa taaaatatca tcaatctggg acatagacac agattgtcct acatttaaac
    80221 ctgttgtaaa agcactatct gaatatgtta aatctcataa tataaatgat atatatgtaa
    80281 gtaaatttaa gaaaatagga actgataaaa attttgaaaa cacatctgaa aaagtatatg
    80341 aatggaatca tttatatata gaattacctg atagatttgt ggataaaact aataaatctg
    80401 taggagatat taaaggaaga attagagatg ttaagaatgt atttaaacgt tcattggatg
    80461 aaataagcga agatagtgta tctatagtgc tagacttaat aaatcaaaag tctctctata
    80521 agggggagga atggcaaaac ccattgatag aatttctaaa atataaaaga aattatatta
    80581 aattacaaac tgaaactgat aagcaaaatt tcgcatggga acaatctgta aaagctggag
    80641 ttgttatagg taaaatgaga aatcatagta ttggtacttt attacttgat atatcagaag
    80701 gagttgaatt agataaagct gtaaatagat atgaaaaaat agtagctcca tctaactata
    80761 aaagaccaaa ggcgatatat actaaaaaaa tgttagacga agcaaagaaa actataactg
    80821 aactaggata tatggattca cttcaaagaa gacacgctac aatagatgat attactgtaa
    80881 ataacatatt atttgttaat aaggattcag caaaacaaat gggagaattt gatatatttg
    80941 atgaaatgtc taaaggcata ggtatagatt ctaagaagtt ttcaaaagta gaagaattaa
    81001 atatagaaga gtttattcaa aatgttctac caacatcaaa agaagttgaa ctgttattag
    81061 aaaatagaca tatagacaat tttgtatcat taatagcacc agttaataag gatgccaaat
    81121 caatgttgaa atgggataat aactttggat gggcttacgc tggaaatatg acagatagta
    81181 gcatgaagga gaatgttaaa aatgcaggtg gaaaagtaga tggcgtatta agatttagta
    81241 ttcaatggaa tgataccgaa ttcgataaca acgatttaga tgctcattgt atagaaccaa
    81301 atggaaatca tatatatttt ggtaataaaa cgaattactc tacaactggt atgttagata
    81361 tagatataat gcatccaaaa agaggtaatg ttgcagttga aaatataact tggtctgata
    81421 taaacaaaat gagattaggt acatataagt tttatgtaaa taattactcg aagagaagtg
    81481 gaatatctgg atttagagct gaaatagagt ttaatggtga aatttattca tttgattata
    81541 acaaaccttt aagagatgga gaaaatgtaa tggttgctga agtaacgtta gatataggta
    81601 atagatttaa aattaagcca ttgttacctt ctaatgtttc aaataaagaa atatggggat
    81661 taactacaaa tcaatttata cctgtaagtg taataatgaa ctctcctaat tattgggatg
    81721 ggcaacaagg aataggaaat aaacattatt tctttatgtt gaaagattgt ataaatgaag
    81781 aaacagtaaa tggtttttat aatgaatatc taaaaaatga tttaaatgta catagaaaag
    81841 tttttgaagc actaggaagt aaaatgtctg ttccttttag tgaaaatcaa atgagtggat
    81901 tagggtttag ctctaccaga agaaatgaag taattgtaaa agttagagga agttatgaaa
    81961 gaatattaaa aataaaattc taaagagaga gaggtaaata atagtatgga aaatgtattt
    82021 gagatggcaa caagaaataa atttagattt gaatttagag gattaatttc agttgaggat
    82081 ttatgggatt taaaattgga gcagttagat gaagtataca aaaccttaac aacagatatg
    82141 aaaaaagcta atgaggagag cttattaaag ataaaaacaa aagaccaaaa ggaagtagaa
    82201 ttaaaaataa aaatagttaa atatatagta gagttaagac ttgcagaaat agaaaataga
    82261 aataaagaaa agaagaaaaa agaacaaaag caacatatat tagagctaat aaataagaag
    82321 gaaaatcaag aattggaaaa taaatcaata gaagaattaa aatcaatgat taatagttta
    82381 gagtagttct agtaaaagat gctcttgttt aatagagcat ctttgaataa aaaacagatt
    82441 ctaataagaa agggtgttag aatgtggata gtaaaataga agttggaagc atatggggat
    82501 tagaagattg gatagcacaa cctcaatatg taggaacaaa agttaaagtg gtttctattt
    82561 catatataga agaatttaat aaaagactta taacgtttat ggaaattgag gaaaaagaag
    82621 aagatacttg gatagatgca gattgggaag atgttttttt aaatgatttc tttaaattag
    82681 actaattaaa acaacagttt taaataaata aaatttaaaa ggaggattaa taaatatgaa
    82741 taataaagta ttgatacatt taacgaatgg agcaatagta gatataacaa cagagcaagg
    82801 atactcaagt ggatgtgaaa catgtgacta tggtacccgt tatataacag acttaatgat
    82861 aatatataag aataaaaaga aggatattat aagagatgaa tcgatgtatg attatgggat
    82921 atctttgtca tctattatga aggttatctt aaatcatcaa gaagatatag aaaagttaaa
    82981 agaagaggag gtagcagaat ttataaaaaa taaattagaa aatgagcatg attgtgatga
    83041 attaaaaata ttcaattaaa atacaggatt taatatcaat agaaaattta gtgctagttt
    83101 tataataaaa gttttggaat atgctaaaat gaatataagt aaaagggtga tataattatt
    83161 agttggaggt aaatatgtgt aaattttgtg acagtataaa agatatgaaa aaacatgaaa
    83221 ctagaagagt aagaatttct tctgtaggaa tcaaaggaaa agatactact tatgagagta
    83281 tagaactttt agaccaggaa gagtattttg atattagttt ttataaattt aaagaaggga
    83341 atataaattt atcagtagaa cacaatctaa ttgtcaaaga ttcaaatcaa aatataaagt
    83401 taaatgtgga tagatttgca ggaggaatac catttaaata ttgtttttta tgtggggaaa
    83461 aattaagtag tgaaagtatt gattttgaga attacataga taatttgatg attttagaag
    83521 aataggattt aattaaaaat gagcacatta ataatataag tgtaaattga cttatattat
    83581 taatgtgaaa ttataatact aggagttatt tttatagtat tataatttga aatgaaaaag
    83641 tgagaaatag ctattgatgg taaatttgac aagaataaat agtttagatt ttacaagaaa
    83701 ggagcttaga taaaacatgt ttgatatgat aataaataaa gaaatattca aatacaacaa
    83761 tgaaaatatt tatgatacat tgataaatag tttttctaac gaaactcatg aagatgatat
    83821 taaacaagga gaaacaataa taatttttac tacaaacaaa caacttgtct acaaagaatt
    83881 aataagagca gctataaaaa ataaatatac tctaataaag catagaaata gaatcaaaca
    83941 taatatagaa atagagttaa aagttcttaa cacagataga ttaataaaat ttttaatatt
    84001 tgatagggat ataaattatc aggagttgag agggtacagg ggtgaatgtg taatagtaga
    84061 tgtaaacact tcaaataaaa ctatccaaaa tttcattaca gagcaaataa aactagtctt
    84121 actttttatg aatgtatata aaaaagaata taagcctttt catggagttt tactatttaa
    84181 ataaaattaa aaaggagaat atgatgaata ttaatactaa ttatgtaagc acaaatatga
    84241 ttgttatgga tatatccaaa ggccataata tagaaataac taaagctatg gttgaaaaat
    84301 ctatacatac ttttaaaaat gcaccagtta tatataatcc aaatcaagaa ttatcagatt
    84361 atagagatgc tgatagagta aatgattttt gtaaagatga agttgtagga attataatgg
    84421 atgtagcaat agtagataac caagttatag gaaaaatact atggtatgac aattgtcata
    84481 ttaaagagaa atatgataat tggtacatta gtttaagcga tgataaatcc gaatttattt
    84541 taaagggggt cgagatatct taaaagatta ttaaaggagt gtagatatgt taaaaaagga
    84601 ttggaaggag aataaatgga aattaaagga aaatataata aagcaaaaat atttacagat
    84661 aatgtagata gtacaacaat aagtcaaata ataaatttat gtaatcaaaa ggaatttaaa
    84721 gaatctagta taagaattat gcctgattgt catgctggta aaggatgtac aataggaacg
    84781 acaatgacta taagtaataa agtagtgcca aatctggtag gggtggatat aggttgtgga
    84841 atggctacta ttccattaga aaaatatatt aataatataa attatacaaa attagataag
    84901 attataagag attatattcc tcatggattt aaaatacata ataagtcaag agaaaaacta
    84961 ttaaagaatt tatttaatat agacataaat aatcttagat gcgaggtgaa taaaaataga
    85021 gcatatatgt cgttaggaac tttaggtgga ggcaatcact ttatagaagt tgataaaagt
    85081 gaaaaaggtc aaatgtatct tactgttcat acaggttcaa gaaatttagg aaaacaaata
    85141 gctgattatt accaagacaa agctataaaa tattgtattg aaaaatataa aaagtcatat
    85201 gatgatgcaa aagagttttt aatatctact ctaaaaaaag acaataaaga acatttgata
    85261 aataaatatt tgaaagacct tagtgataga aaattgaata agccacatga tgatttatgt
    85321 tatttagaaa atgatttaat ggaagattat ttacatgata tgagtatagc tcaaaaatac
    85381 gctgctgcaa atagaatggt tataattgcg gatatattgt ttaaatataa cagcctagat
    85441 gtaaattatg accattttat aagagatatt aaatgtgatg ttatagaatg tattcataac
    85501 tatatagata tggatagtaa aatacttaga aaaggagcaa tttctgcaaa taaagatgaa
    85561 acagtaataa ttccagtaaa catgagagat gggattatat taggaaaagg taaaggtaat
    85621 tctgagtgga attattcagc accacatgga gcaggaagaa ttttatcaag aggaaaagct
    85681 aaagaaaaaa tatctttaga tgaatttgaa gaatctatga aagaaatatt tacaacttgc
    85741 gtaggtcaat caacattaga tgaagcacca caagcataca aacctataga gaacatctta
    85801 aacaatatag gagatactat tgagataatg gaggtgttaa agccaattta taattttaaa
    85861 agcaattaga atcttgttat ttaaataaaa tcaaaaggag aaaaaaggat atgataaaat
    85921 taataacaca taatgattta gatggtgtag gttgctgtat tatagcaaag tatattttac
    85981 gagaacaaat agatgttaac tattgtaatt ataaaaatat aaatgatgta gtattagata
    86041 cattaaaaaa tcatgataaa tatgaacaaa tattaataac agatatatca gtaaatgaag
    86101 atgttgccaa gaagttagat aggattaaaa ataaagttca attgcttgac catcatccaa
    86161 cagcactatt tttaaataat tatgattggg ctaatgtaga aatagagtgt aacaaaggca
    86221 aaacatgtgg gactcaaatg ttatttaatt atttacaaag atgctatgat gatacttcag
    86281 aatctacatt aaaatatttt atagaacttg ttagaaggta tgatacatgg gaatggaaag
    86341 ataaatataa tgatttagat gccaaatatt taaatgattt aatgtatatt atgggaatag
    86401 aggattttat aatggacatg ttaactaaaa tagatagtga tgagatgtgt ctatttgata
    86461 aattaagttt aaaattatta gaaataaaac aaaaagaaat agatagatat gtagagaaaa
    86521 aagatgaaaa tataatggtt aaagaaattc taggatataa tgcaggaatt gtatttgcag
    86581 aaaatcatat aagcgaatta ggaaataaat taagtgagtt acatccagaa cttgatttta
    86641 tagttataat taatcgagaa atcatttcat atagaactat aaaagataat ataaatttaa
    86701 gtgaaatcgc taaagtattt ggaggtggag gaaatccgaa agcatcagga agtcagattg
    86761 atgagagttg tatagataat tacataaaag atatatttaa tataaaatct taattttaaa
    86821 tggaggtata tatgaaattt gaaaacaaca tgattaaata caatttagat ttaataacta
    86881 tgatatgtaa gatgaaacta ataatttatg aggtgtaata atgatgatag ataaattcaa
    86941 ttatgaatta tataatgagt ttccacattt atcaccaata atagaattgt ataatttaaa
    87001 tatagagtac ataagagaag ttgtaagtat acttatcaat acagatatga catttcaaag
    87061 gtttaaatat tccaaatcta gagttgagtg ttctatgaaa gcgtatatta tttcacctaa
    87121 tagtaagcta agtgttgtat ttgcatacga ttgtgaatta aatggaattg acttagacaa
    87181 cctgaaggca attatatgag tataaacaaa taaaaataat actttacaag aaaggtaaat
    87241 tgaatatgtg taagttttgt gaaagtataa ttgataatac aaaagatata cttttaacct
    87301 caagaagtag attattagaa gataatacat gtgaaattat agcagaagat aattgtaata
    87361 attgctatga tggatgttat gaatatttca aactaaacgg atataaaagt agaggaaata
    87421 tatatgttaa tattgactac tacaaaaata ttagaaaaat aatagttgct ccatgttcag
    87481 aatcagtaca tataaactat tgtccatatt gtggtaaaca agtttctaaa gatataaaag
    87541 attttaattg tattcctggt catatagtag atgttagata taaaaatggt gatgtatatg
    87601 attatgatat ggaaaagtct gtacaagaag tcatggataa tgcaaataat aattaaataa
    87661 aatgatactt ttaatagggg ataaatatga atctttggtc taaaattgaa gaaccagtga
    87721 tgagagcagt aggtggaata gtatttaata tatggggaaa tgtttgtttt tccatatatt
    87781 acatagaaga aaataaacaa atagagttag aaatatatga tagaccttat agatatgaag
    87841 gtaaaaaaaa tagttgttga gaagttattt gattacaagt taataaatgc agattataaa
    87901 gaaatacatg atattgtttc tatgatagaa agatttttac tagaaaatta ttaaaaggag
    87961 atatttaaaa tgaataaagg aattaaaaac tatataacag cagtgaatta cttacttgat
    88021 aatttagagt atatgatgga ggatgacgaa tttaataatg aaaagttaca gaaaagaatt
    88081 gatgtaatta gaaaatttga aagagaatta taagatggga aaaataaaaa atggagaaat
    88141 agatactgaa gattataggc tttttaaaaa cattcaaaaa gaaaaagata gagtatatag
    88201 taagtacatt aatgaagaat acataatgga agaattcata aactacttaa gattggaaga
    88261 taaagattat actacagaaa tattagaaag atatgcacga tatattgatg aaaatttaga
    88321 caatcgttgt ccatattgtg tatataatat ttgtagtgaa catgataatt gttttgatgg
    88381 aatacttgaa aatttaaaag aaaaaattaa aataaaataa atattttaat atgaaaggat
    88441 gttgtgataa taagtataag agaaattatg gaaatagata tagaaaatct atcaatgaag
    88501 cagcatgaag tgattaaaat atagaattat taaaaaaata tgatacatat atatataaga
    88561 aggggcatta tagagaaatg ataaaagaga gatttaaagc aaaagatagc tttaatatgg
    88621 atgagttcac taaaatttgg cttatggatt ttaaagaaga ttttgattta agcttaaaga
    88681 aaatgataga aaatacgata aaaaaatcaa taaaagatac ttatgaagaa acagaaaggg
    88741 cgataacaaa tatagaaaat cttataaata aactataagt caaaatatta ctaacgacac
    88801 ctctaatata agattagtta tagaggaaat ctattattag agaaggcata gattgcgtca
    88861 ctggaacaat tcaagttaaa aacttagata atcatatcaa ataaaatctt ttacaacaaa
    88921 tcaaaatttc taaaataaat tcttattaat aattcaatta aaactaaagg agtgaaatta
    88981 tattgaaaaa gtttttatta acagggttat taggaacaat gttaatagcc atgtctggat
    89041 gtacaggaat acaaagttca atgaaagatg ctgaaagtga tgtatcaggg cttaatagaa
    89101 ctgtaaatgt atattcagat aatggcgagg tattaaaaac atatacaagt aaaagcatga
    89161 gagttaaaga tggagatggt ggtactataa cactagattt tgatggtaaa agggtgatta
    89221 tatgtaatgc tcatgtagta atagaagaaa attcatctaa taaataaagg agagttaaat
    89281 gtttaaaatt ttaaaaacaa ttcttataat aatttgggta gtagatattt taaacttccc
    89341 acaatttcaa ttcttagata caacatatcc aatcaatacc ttagcatggt tgctaatctg
    89401 gattcttata ccatcgagta gtatatatat tgacaaaaaa gaataaaaga aaggagtatt
    89461 aatttgattt taaatattgc tacaattttt aatttaggtt gtatggtggc taattacttg
    89521 caagataata ctaatgggat actacttaat ggattttgtc ttatagcatt attattattg
    89581 aataatgact tagattaaaa gtattatttt aaggagatta aaagatgaaa ataacaatat
    89641 caattgaaga agcaatggat attattaaac aacactatga gaataaagga attgaaatca
    89701 aagacttaag ttttaattta gaaaaaactg gaatggttag aaatattaaa tttaagggag
    89761 aaataatact taagtaggag atatttatat ttgttaaaaa aaaggggaag atatttataa
    89821 gtagtacaaa tagaagtgat gctagaagtt tccatataag tgattattat agaactccaa
    89881 ttactaaaat caaagagttt ttaactgagt tcagtagata tgaaaatata ctcaattcaa
    89941 atataaaaat attagaccca tgtgcaggtg gagataatac aaatccaatg agctatccaa
    90001 ctgcaatcca agaattttca aatcaagaaa tttcaataga tacagtagat ataagagatg
    90061 attcaagagc aaatataaag caagattatt taaagtttca gccaaaagaa aaatacgatg
    90121 taattattac taatcctccc tttaatttaa gcttggatat aattaataaa gctttaaatg
    90181 atgtaagaga aggtggtttc gttattatgc tgctaagatt aaattatctt ggaggaaaag
    90241 taagacaaag gctgtgggga aataatatgc ctaaatacat atttgttcac aatagaagaa
    90301 tgagttttac agatgatgga aagacagata gcatagaata tgctcatttt gtatggcaga
    90361 aggggtataa tccaaaattt tctcagttaa aagtattaat aagtcaatga aatagaggtg
    90421 taaagtttat tagagatgga aataaataga agaagatgtg agtatgctgc cagaacagga
    90481 agatatccta attctcttat tttgtgggaa ggttactata gccttcttaa tatccaatat
    90541 atagaggata aaacaagagg atatattact aaatttaatg gcatggatgt tataaaatgt
    90601 aatgactttt taaaaataga attatttgaa aagaatatta ataattaaaa tttgtttttt
    90661 aagttgaggt gatgagttga gatataataa ttatcatagt cataaaattt attcaaatat
    90721 aaggtcgtta gatgtaatta ctaaaccaca acaatatata gatagagcaa taaaactagg
    90781 tcaaaataca tattttacga cagaacatgg atatcaagga aatgtatatg aggcaaaaac
    90841 tttatgtgat gaatataaat taaaaatgat tattggagca gaattttact atgtaaatga
    90901 tataaatgag aaagatagag gaaattatca tttaatagta atcgctaaaa ataatgatgg
    90961 ttacaagcaa ataaataaag ctttaagttt agctaataaa aatggatatt actataaacc
    91021 aagaatagat gaaaaaatat tatttgagat atttaaacca ggggatgtag ttattactac
    91081 tgcatgtgta gctggaatat taaaacttga gaatagagaa gaattaatac taaaactaaa
    91141 gaattatttt aaaaataatt tctttcttga agtacaatct catcctcata aaactcaagc
    91201 tttgcacaat aaggatgttt tagaattaag caacaaatat aatatagata taatacacgc
    91261 caatgacagt cattatattt atccagaaga atcaaaatat agaactaaat ttcttaaagc
    91321 taaaggtata aattatcctg aagaagacgg ttttatttta gattatccaa attcagagga
    91381 tatatttaaa agatatgaaa aacaaaatgt attaacaaag caagaagttg aaagagcatt
    91441 aaaaaatact ctaatatttg atgagtgtga agaaatcacc ttaataaatg atgatataaa
    91501 attaccatca atatctaaaa atccaaataa agaactgaaa gaaatattaa ataaagaatg
    91561 gttagagaaa agaaaaaata tacctaaaaa tagatggaat gaatacttag atgctataag
    91621 gtatgaattt gatattatag agaaaactca tatggaggat tactttatta tagattataa
    91681 aatagttcaa agagcaaaac aagaatataa tggtcttctt actaaaacag ggagaggttc
    91741 agcaccttca tttataataa ctaatctttt agggcttact gaaatagata gattaaatgc
    91801 tccagtacca ttattcccta ctagatttat gagtgttgaa agaatactat cagcaaaatc
    91861 tttgccagat atagatttaa atgctgaaga tgctgaacca tttatacaat caactagaga
    91921 tttattagga gaagaaaatt gtgcatggat gataagttat aagccattac aagatgcttc
    91981 agcttttagg ctatggtgta aagcaaatga tatgaaacta tctgagtatg atgaagtagc
    92041 taaaaactta gataaataca caaatgatgt tttttggaaa gatgtaataa aggaatcaaa
    92101 ggtatttgta ggagtagtag aaagtgtttc tttctcacca tgctctatgc ttatatatga
    92161 tagaccaatt gatgaagaag taggattatt aaaaactaag gatggggtat gttgtaatat
    92221 agatggatat tattgtgata agtataaata tttaaaaaat gattatttaa cagtgaaagt
    92281 atggtcatta ataagaaaaa tttgtgaatt agcaaatatt agtattccta caattgaaga
    92341 actaaacatc ttattagatg ctaaaaccta tgacatatat aaggacaaat taacttgcac
    92401 tataaatcag gtagattcag actatgctac aaacctggca tctaaataca aaatatctag
    92461 tgtggcggaa acaagtgcat ttgtagctag tatcagacca ggatttgcat ctttattaga
    92521 caattttatt aacagagagt catatacaac taacgttaaa gaactagata tattattaga
    92581 agatagttat cattatctta tgtatcaaga atcaataatg aaatatttaa tatggttagg
    92641 aatagaggaa tctgagagtt atgatattat aaataagatt aaaaaaaaga gatttaagga
    92701 aaaagagttg aaagaattgc atatcaaact aaaaaataac tggattaaaa aagtcggaac
    92761 tgaaaataat tttgaagata catggcaagt tgtaaacgat gctgcctcat attcctttaa
    92821 tgcttcacat agtctttcat atgcatatga cagcttatac tgtgcatacc ttaagtcaca
    92881 ttatccattg gaatattata ctgtagcatt caatttatat aatgaagata cagagagaac
    92941 aagaaaatta acagatgaaa tagagtattt tagtattaaa ttagaaaatc ctaaatttag
    93001 attttcaaaa tctgaatact tctttaatag agacacaaat agtatttaca agggcattga
    93061 atctattaaa tttttaaatt ctgatatagg agagtatcta tattctctta aagataataa
    93121 atatgattca tttttagagc tattaataga tttgcagggg catataaact ctaaacaatt
    93181 atctatactg attaagctag atttctttga ggaatttgga aagtccaaca aacttttaga
    93241 gacttatgat atctataact caatctatag taaaaaacaa tttaaaagag ataatttacc
    93301 atgcgatata aataccatga gaaaatactc taataaagaa acagaaaaaa tatttaaaga
    93361 agttgataca aaagaattat gttcttatct tgaaagtcaa attgaaaata cagatatacc
    93421 aaccaatgaa aaaatacaag ctcattttga gtttgtgggt tcatgtaaca taaaagatag
    93481 caattcaaat ccaaggtatt gtttagtaat agatatagat actaaatatt ctcctaaagt
    93541 cacattgtat aatataagtt caggaaatat aaagattttc aaagtaagta aacctatttt
    93601 tgaggataat aaaattgatg tttatgattt agtttattta aaatcaatta aagaaaaagc
    93661 taaaagtaaa aaagtagatg gaaaatggat taggagcaat acagaaacag aatggtggat
    93721 acaagaatat tggaaaatag aaaattaaga atatgacctc gtatatgcgt ttctaagagt
    93781 ttacataaga gtctgcttgt atttatacat tgatttctta aaatggcata tacgaagttg
    93841 gtgaaaggta gtgatttcaa tacttataga tgaacaaaga tattatagct tattggaaga
    93901 aaaaaaagac ctaagtatga gaatcgatga attaaaagag gaaaatgctt ttttaaaaca
    93961 agaaaatgaa gagtatgaag aaattcttaa tgagtgggaa tgtgtaagaa aagaaattgt
    94021 agcaacttgt aaaaaaaaag aaatattagg tgaaaaacca agtgaattag aaatggttct
    94081 tcaaaaaata gaggatatat aatgagtgta aataaaattt atgagaaaaa agaatacatt
    94141 attatcaaat caaaatctgg atatatagtt tataatacaa ataaagagtt taaagaaggc
    94201 cacactcact taaaaagtta taatgctgct aaaacagcta tagatttagt tattaagaga
    94261 aggcttccta aaagttattc tatttatttt cttacaagtt tgatgagaat atctaatgat
    94321 gtacaatata taaaacatat aagcgatatt gtatatataa gaaataataa aggactaaaa
    94381 gaaaaatata taaattctaa aaatattaaa aaaaactatt gagaacatag aaggtatatg
    94441 atatactatg aatataacaa gaacatagaa ggtaaaaagg aggtagtgat taatatttga
    94501 aatcttataa agaaaaacag tttttagtat ttgaatttga agatgggaag aatgtaaagt
    94561 ataatttggc aacaggagaa tacgttggta aatctggaag gattgtaaaa gatgtgtgta
    94621 ctcaacttag aggatataat ttacatgagg taataaattc ttttgaagat gaaaattata
    94681 agtgtttttt aaattttgta gatggaagag taaatagaag taagagtagc agagcttggg
    94741 gaaggagggt tgaaagaata agaaatatag gaagtttttt aaatgaaata aataattatt
    94801 ctgagtatga acaattattc tcagcaggat taaaaaaaat aatttatccg atacattgtg
    94861 atattaagag tatacctaaa ggtcttattt ctatctgtag gaattatagt attactttga
    94921 gtgaccgatt gatacaaggg tatagtaaaa acccaaattt gtataataat ttattaagtt
    94981 tagaattgaa ttcaataaga aaaactaatt taatttcaat tcttgattct ggttatgata
    95041 gaatgatatt tgataggtta atagacatat ataaatataa acctcaatca cttataaatt
    95101 atatagataa tctgatgaca tatgaagcat taaatgggct tgaaagcact ctaaacgaat
    95161 tatatgacta tgttgttatg atgagtgtaa taagtgataa atatgaaaaa tatccaagac
    95221 atttcttaac aactcataaa atagcatctc gaaattataa tcgtcttaaa actcaatttg
    95281 aagaagaagt atttaataaa agaatagaca agtcactaga atattcatat caagattata
    95341 aatttatata ccctaaaaat acaaatgaaa ttaaagatga agcagtacaa caaaataatt
    95401 gtgtaagtag ttatattcaa aatgttatag atggaaaatg tcatatatta tttatgagaa
    95461 aaaaggataa tctaagtaaa agtttagtaa caattgaagt tagaaatggc aaaatagtcc
    95521 aagctaaagg taaatataat agagatgtca atgaaagaga gcaagaagca attgataaat
    95581 ataataatag aatagaaagg atgaagaaaa tatgttaata gaaggaacta aaataagatt
    95641 aatgaaagaa atacaaggtt ttgagatttt aaagcatcag ctacttgcca tgattcagat
    95701 gagtttgaat acaataaagg tattaagtta tgtctagcaa gaattgaagt taaaaaagca
    95761 aagaaacagg tgaatttagt attagatgaa ataaataata aataaattta ggaggtctaa
    95821 aaatgacttg taaacttaaa gatatatgtg aaaataagaa tactgattgt gattattgtt
    95881 gttataatcc aaatacatat ttagaggatg cttttgaatg gaatggagaa ggaaaagaac
    95941 cgtctagtga agaattggat gatgctcttg cagaataaat aagtatttaa aatgataatt
    96001 ttaatatgat tggaggtctt tatgaggtgg agaaatatat tagtaacaag tgttttagta
    96061 atgggtagta gcatacatat atttgctaat actaaagaaa tgagtactag caggatggat
    96121 aaaaatattg tagcagatac agctaaaaat attaacttaa tgtataaata tgagtgggag
    96181 caacacaaaa acagttctga atataaatta gaaatcaaga gaattaattt agaaaagggg
    96241 ttaggaataa aaatagaaaa attgattcct gtaacatggg aagtaagtta ctatacttct
    96301 ttaaactgtg aaaatagtaa atatggagct attacagcta caggagaaaa attacaatat
    96361 gggtttgtgg ccaataatca tcttaaattc ggaactaaaa tattagttga tggaaattta
    96421 aaggtggtta aagatagagg ttctaataaa tattttggta attctaatgc tatagatgta
    96481 tttgtaccaa aattagaggg ggagagtgat tataaatatt ataagagagt aaacaacatg
    96541 ggaagacatt ataaagaagg atatattata gttgaaggtt aggagttgat aaattgaatg
    96601 taaatggaat aaaaatacca ggaattattg atgtgtcaaa tgtgtatgtt tatggaatta
    96661 aagaaagcat aattgcaagt ggttatccga tgtatgaaca acaggtaata gatatgaaaa
    96721 aaataaacat ttcagaaaaa gatttaaaaa gagcaaatca attaggcaaa tcaaaacaag
    96781 gttcaggtca tgattgcttt tctaaaggaa ttatcattca aatggattta caatggtcag
    96841 aatatatgtg gagacaatgg gacagatatc atcataatga ttatgtgtct agtcaaagta
    96901 aaatgcatag attatctaaa tttaatcttg atgatatgtg taataaatat gttgataaaa
    96961 atacaataaa ttttctaaat gaattaattc atgagtacaa taactttgaa gaattgaaat
    97021 tgaataattc taataatatt attcttagaa atggagaaaa agttgaagtc acaaaagaaa
    97081 ctctttggaa aatcataata tcaaattgcc catcaggatt gatgctaact gcaagagtta
    97141 cattaaatta tctacaaata aaatctatga taaatcaaag agaaaatcat aaaatggagg
    97201 aatggagaat tctgtgtgac ttttttaaaa cactaccaaa atataaagaa ttaatgatgt
    97261 aatagttttg ttagcaatta aattttaaat ataaaggaga agtgggtatg gcagaaaaaa
    97321 gaataaatta taatcaagta tttgtatcag gagaagtttt agacatttta aatatagcta
    97381 gaatgaatca aggaactggc caagaagcta taagatttac cttaaaggtt gaaacagcac
    97441 caaacgaatc ggtaaatgta gattacttta catcaatgtt taagtcagat ggttcaccaa
    97501 atcaaatgtt tttaggaata gagacaatag ctaatgaaat aaaaactaga gcagaagatg
    97561 gaaaaggtga tattgttaga tgtgtttgtt cattagacaa taacttatat tataaagatg
    97621 gtgaaaagaa agagcgattc caaatatcag gaactttttg caatagagaa aaatatgatg
    97681 acaaaggtaa tcctattgat gacaaaggcg aagtagtaaa gtcaataaaa gcgagtcagg
    97741 tctggagagt atatacatta attgaaaata tagaagaaaa agaagatgat ttaggtaagt
    97801 atttagagat taagggttta attaataaat atggtaagca aggttgtaat atgacattta
    97861 gaatacataa tgaagatatg atagaaggat ttaaaagttt atataaaata ggagatgttg
    97921 gccttcttga aggtacagta aaatctatgg ttgttagtaa atcagcagga tttggttcaa
    97981 gaattaaaaa aagtgctttt acatttttag aaatagaagg tggcgatgaa cctttgaaag
    98041 atggagacaa aatatttagt gataaaaatt atcctttcac agataagaat atagaggcaa
    98101 tgagagaaaa aataaaagaa aaagatgaaa aagaaaaaca aagagatatt gataaaaatg
    98161 gtaagacaat tgagataagt gatgatgatg taccatttta aattataaat taaataatct
    98221 attaaaaagg agagatgtga atggaagtta aagaaaaaac aatgaatgat ggtttcaaga
    98281 aagtggtaaa tgaggaaata aagacgtata tatcaaattt atattcagat agaatagacg
    98341 gattaaaaga gagtgatagt caaattgaga taacaaaagc attaatagcc tttcatttag
    98401 atatagaatc aattccaaag gataatacaa acccattttt caggtctaaa tatgcaaacc
    98461 ttgatacaat tcttaaagca gtaaatccat tattagcaaa acatgattta atactaatgc
    98521 aatcagcaga agatgcaggt aatgataaag tatatataaa aactaaacta aagcattcat
    98581 caggcgaata catagagtca aattctgcac catttaaacc agctaaaact aatgatatac
    98641 aagctagagg agcattggaa acttatttga gaagatatgc agttcaatca gtattagcat
    98701 tatcattcga ggaagacgat gatggaaatt ctttaacaaa caaatcaaag ggtaaatcag
    98761 aggaagaaaa ttcaactatt aagaaaagta gagtgtaaat aaaattgcta cctcttaaat
    98821 gaggtagcaa taaatacata acataaggag gggaaatctt gaattgtaag tgtaggtttt
    98881 gtaaaaagaa attaaataca aatgatgctt ataaagtaga gcatattaca tctgggggaa
    98941 ataagcagaa tagatattat tgcaatgaac aggaatatag aaaagagcaa caggatatat
    99001 atttctggaa acaatgtcaa cttggaatag attatattat gggatataca gttataaata
    99061 atcaaaaaaa taagatgtta caagagataa taaaaggtgg ttatacgaga gaagaattat
    99121 atgattgcat cattgagaag aaagatgaag ttatagaatt acttaactat agaaaagata
    99181 tagaagaaga atatcctaaa ttatgttatg tgtttacaat attgaaagga agtattagag
    99241 atataacaat taaaaacaag caaatgaaat atgaaaaaga aaatgaaagg atatacaaag
    99301 aagtagagaa aagtgaagaa tattatgaaa taattgctcc taaaaaagta atttataata
    99361 aaagacaaag tttatttgac aaagtgaaag gagtgtatca agacgagtag ttatgaaaaa
    99421 ataatagagg ataggggtat tatagaaaca ttggttttag gcacaatgtt aaaatcatta
    99481 actcttttta gtgaatataa aattagcgaa agtgacttta taatagataa ggtaaaattc
    99541 tttttctcgt taggaagaat aatgtctaaa acacataacg agcttgatga aataagtgta
    99601 gctaaatttg tatcttcaaa taaactcaaa tctgaatatg aaagatatgg tggttggaat
    99661 agcttatcat ctgctatgga gtatggaaaa gaaactaata tagcagcata tattgatgat
    99721 ttagctaaga ataatttact aattgcttta gataaaagag gttttaatgt aataaaagaa
    99781 atggagcata atgggttaaa atttattcca tttgaaatat ttcaatctat gaaatgtaga
    99841 gaagtggaag aattttatga ggggttaata tcttcatgta gtgtaaattc tataaaaaat
    99901 aatatgaaag ttgaaaatct tttacttact aaagatgata gagaaaaatt aaagcaaaaa
    99961 actgaagcag gaacacctta taatattata tttgaataca ctgaaaaaga aataggattg
   100021 agtaataatg aagaatctaa gtatatatat agcttaccaa tattatcaaa taggactaat
   100081 gggattggta agggtggtgg tataaatata atagcagggt tttcaggcat aggaaaaact
   100141 actttactat tttttaatta catattagct atgatatata gaggagagaa gatagtcata
   100201 tttgcgaatg aacaaaaatc tcaatatttt aagagtatgt tagtatcgtt tatagcatat
   100261 aacatattta attatcatga tttagataga aataaaatag ataatggaga ttttacagac
   100321 tttgaagaag acttaatgga aaaaatagaa aaatttttaa gagatagatg ttttgcagag
   100381 aatctaaaat ttatctatat ggaagaattt gaaatatctg aaatactaag gaaaagtaaa
   100441 gaacttgtta cacatcaggg atttactgga atagcagtgg atacatttaa atcagaagat
   100501 tcgtcagatg cacattatac aggaaaatta attgaaaatt ctaaattact cgatagtttt
   100561 gggaacaaat ataatgtaat aactatgtta tctatgcaat tacttacagc tcaagaaaat
   100621 aaaagctcat atctttcggc aggagatttg tcagaagcga aagctgtcaa aaatgtatgt
   100681 ggtttattaa aacttatgag aaaagtagta aatgagttag aattagattc tactaacaag
   100741 aaattctttt taaaaccata taaattaaaa tataataaat taaaaaagac tactgaaaga
   100801 gaatatatcc agtttgatgc aaaagatttg caaaaagaat atagattatt atttttaaat
   100861 aagtcaagaa gaggtcaaga tggagatgta attttactaa gattttatgg taagactggt
   100921 agattagaag agataggaag gtgtgagaag gtctacagag gacaattgtc atactaggtg
   100981 atgactatgg aaataaagga tttgactaat gaacaggtga taaattttat ggaatattta
   101041 ggttcggact tatctcctaa aagcaatgat agacagttaa tattcaatac ttgtttatgt
   101101 cataatggtg attcatacaa attattttat tatacagaaa gcaaaacgtt tcattgctat
   101161 agttcttgtg gccatatagg tagcttaata gatttattaa tacacataaa taaatatgag
   101221 tttaaagatg ctattaatga aataaaagat ttctttggta tttcaaatca accaatgcta
   101281 agaaaaggat ttagaataaa gaaaaaagta gaacagatac atgatattaa agatatacaa
   101341 atagaattac ttcctacccc taaaaagcca tatgtatata aaacttttca gcaagtccca
   101401 attgaagagt gggaaaatga aaacatatct tttgaagtcc ttaaaacata tcaagtatat
   101461 tataatctat atgaaaatca aatagtaatt ccacatttct gttggcatga tagagctagg
   101521 cctgttggta ttagagttag aaacttagat gaagataagg ctaaaagttt tggcaaatat
   101581 attccattat ggtacgacaa taggtgctat aatcatagat taagtcttaa tctatatgga
   101641 ttaaatgtaa ataaaaaatc tatcaaaaat tctaaaaaag ttattgtatt tgaaggtgaa
   101701 aaatcggtgt tacaaatggc tactatgtat aaaaataatc cctctgtagc tatatgtggg
   101761 agtaatttta gtagagagca aaaaaagata ttaatagatt taggtattga agaattaatc
   101821 atagcttttg atagacaatt taaagttaaa gatgatgaag aatatgttat atggagagat
   101881 aagatatata aattagttca agatattaaa gatgtagtga atataagtgt aatatgggat
   101941 aaatataatt tattgggtta caaagatagt cctagcgata aaggaaagac aatatttgaa
   102001 aaactattaa aaaacagaat taatatagag aactttgtta aacaataaaa aagtaaagaa
   102061 attaatttta tgagaaaatc tttattgttt agggatttat tagcagatgc taaataaaat
   102121 atgtgtttta atatgagtca gaataacaaa tagaggagag ataagatgaa aataatgagc
   102181 ataagtatag atttactatt aaagaatatg tgtatttgta ttcttgataa tggacacatt
   102241 cgagagttat ccaatagaga tataatagct gataaattta tctttgaaat ttataaaatt
   102301 tttaataatc ataattgcga taaactagtg ttagatacat caggaattgg aattgcctat
   102361 tatcaagatt tagagaaata tatagataaa aataaattaa ttggtattta cttaacagaa
   102421 aagaataatt ctaataaaat actaatgaat ttccttaatg atgagtcatt ttataatcta
   102481 ggactagaga tttgtgtgaa aaataatgga ggtagaatat acccagatat gtctaaatac
   102541 gatgaaatag aaagggggat tattgagtgt attatgttag caaattatta tagtaaccca
   102601 tcaatagaaa gtgagtaata tattttaata tgaattggag gtaggttgca tgataaattt
   102661 ttcaataaag gacgtacata tgggagatag attatattgt atgaataata taggaaatta
   102721 taaaaaaggt gaaatttata cagttagtga tactagtttt tttcaactct tccataagat
   102781 taaaggagaa aattgcttac caattgatta ttattttata cacttaccaa aaaaaagaag
   102841 aattagaaag taatcctaag tcaatgacta aagaagaaat agaagatgaa ttaggatata
   102901 aaattaaaat aacgtctaaa taataaagtg aggtgatatt acattgaata tattcaataa
   102961 aaaatatggt agaaatgtaa aaataacaga ggcagaacct ccttctcctc ctcccaaaca
   103021 accaaacttc gatatggata atatacaata tgataaagaa atgaaaagaa agctattaga
   103081 aatggaaaaa ataaaaatag actcagaaat gaaaaaaaat agtgaagaat ggatttggat
   103141 tgaaggatat aagggtacag atagagatat gaaatgtaga aactttcagt atgaactaaa
   103201 taaaacttat agtgttgaag aaatacatag aggaaatata aatatatatg actatggatt
   103261 ccatttgtgt ttagatttaa aagatgtttt cagatgttat aatttaaatt taagtaatag
   103321 atttttcaaa gtaaaagcct tagttagaag agaggataaa tataagtatg agatggaaca
   103381 atctttttca tcaatacgtc caggagcaaa atgtagcata ggtgctaaag aaataatact
   103441 ttttagagaa ttaacttttg aagaattaaa acaagatatc caagacaagt ttcctaaaat
   103501 aaacaatgaa ctggaatgga atcttatcaa aaaattaggt atttataaat attacaataa
   103561 aatatttata aataaaatga aagaaattgg ttattcagat attttttcac aggttttatt
   103621 tgatgaatat catccgttaa taaatccaca tagaactatg aatatacttg acaaggcaat
   103681 tgcatattca aaagaaaatt tatctaaaga tatgataata tatttgctta tgaaagaagg
   103741 ctgtagatga tagtatttga attattaata ataatattta ttgctatatt aatggtaact
   103801 atatttcttt catgtttgct tgtttcaatt agtatgattc ctaaaataat agacgaaata
   103861 aaagacatta ttgataaaat taaaaaagag aaaaaataat atggagttta aaaaggaatt
   103921 agaagttatg gaagattcag aaattaaatt tatacaaagt ttaaatagaa taaataataa
   103981 tatccgaata aatgaagaaa caaaaatatg tttggaaaaa gaaatttatg cttcttctag
   104041 ggttctaagt atgctttgtg atttaaatga aatatattct aaacagaata aataacacat
   104101 taaaaagtta gttttaatag gaggtgttct atggatatat taaaaatcag ttacaacaat
   104161 ctaaacgctg tatcaaaaat atctgatgta ctaagggata ttgtaaatga ggatacttta
   104221 atagtatgta taggtagtga tagagtttta gctgactcat tagctcccat gattggaact
   104281 ataatggaaa aatctaatat taaaaataaa atatttggag tactaggaga ttcaatagat
   104341 gctttaaatt tagaacaaaa aatacaagca ataaaaaata attatacaaa ttcaaatata
   104401 atagccattg atgctggtat aagtaaaatt tcagataaag gaacaattat aattagcaat
   104461 aaacctgtta aaccaggttt aggggtagat aagaagttac tagaagttgg tgattattca
   104521 atagttggga ttataggtag aaataaatat gatatatatg atacttcaga ccctgaactt
   104581 atacttgatt tagctgatgt tatatcgaaa tctttaatat ctatattatt agaaaaagaa
   104641 gaaaggatga ttgtatgata caggaagtca gacaagaaat actattaaaa aatggtttga
   104701 ttttatatac aggtgatttg gtagaaataa aatacaaatc agatgaagat gtaatagaac
   104761 atacttgtaa aggtaaaatt aaagaagcaa aagaattatt tattaaatta gatacaagta
   104821 agaaatataa aacttctgaa agaatgattt attcttggga attaaaagaa ataaaaaagg
   104881 tggatgatga agatgaaaaa gataattaat agtaaatata gagcattata tttatttata
   104941 ttttttctaa ttttcaattt aatatatagt ttatattttg gaaggaatac ggagattgga
   105001 ttttattcta gtacatcttg catagaagaa tatatactgg atattataac ctctatagga
   105061 ctatttttct caatgatgtt agctgggttt gatgttacag aaaactttat aaacagttta
   105121 agggattatt gtgaagaaga tgcaaagtga ggtgaataaa ttggaattaa aggattatat
   105181 aagtaaagta gaattaaatg acatgccatt gaccttagac aataaataca tgttaaatga
   105241 aataagcata tctgaagata gcaaaatctt tgctgtaaaa gacacatcag gaataacatc
   105301 ttattatact gaaatagaat ttaataaact atttagagga attaatagca tcctagagaa
   105361 tattatctaa tatatatttt taaggaactg agggttgaga gctattaatt aatagctctc
   105421 tatttttttg aaaggggaga attaatggaa aaggaactat acagctttag taaattaaat
   105481 gcatttaaca catgtccatt tcagtactat cttacatatg taaaaaattt aaatcgagaa
   105541 caaagttgtt acggttatta tggcaatgaa ttacatagtt tactagaaca attacaacaa
   105601 agaaaaataa caaatcaaga agctattcaa aaatacaatg aagttataga atatgcaaat
   105661 ctaatggatt acaattttcc tacaccaaat tcaagaatta attatttaga atgtatatta
   105721 cattatatag aaaattttgt accaattgaa tgtgatagat actatataga agaatatttt
   105781 gagtttgata ttaatggaat tacaatgagg ggatatatag acttatatta tataataggt
   105841 aataaaattt atgttataga ttataaatcg agtagtaaat tttctaaaaa agacctacct
   105901 aaaaaatcaa tgcagcttat cttatatgca atgtatctta aagaaaaata tccagataaa
   105961 ataattgaat atgtagcttt tgatatgtgt aaatatatga ataatgaaaa aggagtatta
   106021 attgaaagaa ataagattga tagtataaat gattatgaaa gagctatagt aaaaattaaa
   106081 tatactaaag aactagagaa acaattaatt gattttgttg ttgatacagt tactcaaata
   106141 aaacagctag attccaacga tgagagcgtt tggtgcaaaa gtgatgacaa aagtaatcag
   106201 tttttttgta aaactttatg ctctcattat aacaagggtt gcaaacataa ggaaaacaag
   106261 agttttagaa aatcaaaatc ataataaaat gtagatttta ataagattgg agagtgttta
   106321 aatgaatata ccaaagcaag taaaagtagg aggtttattc tataaaatag aagagacaga
   106381 agaacctatt ttagtaaata atcaattatg ttatggatta gctgattatg gaactgaaac
   106441 aataaaatta tctaataatc tacaatcaga aagagtaaaa gaagctactt tcttacatga
   106501 gttattccat tgtatattta gagatagatg tatagagagt gaagatgagg aatatttagt
   106561 agatgtatta agcaagggac ttcatcaagt gattattgat aatcctaata tatttgaact
   106621 taaggtgagt atagatggat aaattaaaaa atatatttgt atttttaggt tattctggct
   106681 caggtaaaga tagtatagta acagaaattt caaagcaatt caatattcca attctaatat
   106741 cacatacaac aagacctccc cgtaattact tagaaatcat taataaaacc tattattttg
   106801 tagataataa attctttaag aaagaaaaaa ataactttat agaaatgaga aagtatatag
   106861 ttcatgatgg cagcacttgg ctatatggta tacataaatc tgaattagag aataaaaaat
   106921 atgctttgac tatagtagat gcaagtggat ataaagcact agaaaaatat tttacaggaa
   106981 caaaaactaa gttagtacca ttttttataa acgcagatga agatactata agaaaaagat
   107041 taatagatag aggtgataat cttaaagaaa tcgaaagaag attagttgat gataagatta
   107101 aatttaaaga gtttttaaat agtgaaaact acattgtaat agcaaataac ttaagtataa
   107161 ctaatgcagt agagcaagtt aaaatacata tgaaagaggg gattcaatgg tcttagcctt
   107221 agatgtatcc atgtcctcaa ctggatgggc agttataaat agaaataaga atatattaaa
   107281 atatggaaaa atagtaacta aaaaagataa attcaagtct gaagatgagc gaatgtgtta
   107341 tatctgtaat gcaattcaag agttaattat aactcataat attcaaatag tcttaattga
   107401 agaccaattc acttcaagaa actctaaaac aattcttagt ttaagaaaac tcttaggagc
   107461 aataatgagg actgtaaaat taaataatat agagattgaa tatatgtatc cagtttctat
   107521 tagaaaatat ctcctgaata atggtaaagc taaaaaggaa gaagtagctg catatgtaag
   107581 agaaaacatt attgatattg gagaatatat tgataggact tgtaaggcta aaacaagtga
   107641 tatatatgat gctatagcac ttggaatagc ttatttaaac aaacttgata ctaatagata
   107701 attttaaaaa gggagattaa attaatgagt ataaatgtta aaataaagaa attaaatcaa
   107761 aatgcaatag tgccatctta tgcaagagaa ggtgatagtg gaatagattt atatacacta
   107821 aaagatacgg tgattccagc taaatcagca gtagcaatat ctacaggtat atcattagaa
   107881 attccatatg gatatgaaat gcaagtcaga cctagaagtg gtataagctt aaaaggaatg
   107941 ttttttacaa gatatgtgac tatatatgat aaagtgcaac ctaaaaaaca aattagaaaa
   108001 atttttgtag cacatccaac tgtaagatta ggtacagtgg attcaggata tagaggtgaa
   108061 attaaaataa ttacatataa tgaagaggat tttgatattt taattcctaa acatactaaa
   108121 cttgcacaag gagtatttca acaagttcca agagctatat taaaagtggt agatgaattg
   108181 actagctctg aaagaggaag taatggattt ggaagtacag gtatatagat gaataagtat
   108241 ataatcctag aaaaatataa ttattactat gatgacaaat gtatgacatt atatcattta
   108301 gaaaatatct atacaggatt aagattttct attgaaaaaa ttgaattaga gtactataat
   108361 atatcctaga ctaactttgg gaggagtatt aaatgtacag atatgatgat tatgtaaatt
   108421 taataaatga cttagaatta ccaaaagaaa ttaggaataa atgtgttaga gttataatga
   108481 cactagagaa catgcaggat attatggtag tacataagtt taagacttat gttgttaatg
   108541 aaaaatatat tgaaaaagta gcataaaata attaagtcat ctattaattt aggtgacttt
   108601 tttgcattta tgtcgaatat ttcatctact tcatattgta ttagatgcta taattaaaat
   108661 atatgtcgaa aggtagatgg tgaggatgtt taaggagata tttgaaaagg tatttatgtc
   108721 agaagaagtt agtaaaactg taaaagaagt taataatatt attaaggata ctaagataca
   108781 agtaaaaggt ggatttggag aacttagatt agattttata cttagcagat taggcaaaga
   108841 ttacataata attaaagaca ttattgtacc aggctcaaat aagactacac aaattgatag
   108901 tattgtgatt tctatgtatg gaatatttgt tatagaatgt aaaaatttta gtggatatat
   108961 ttacggaaat gataaagata aagtatggac tcaaattgta ggaaaaacta aaaatacatt
   109021 ctataatccg gtaagacaaa attatgctca tattaaagca atagaaaata taataggaaa
   109081 taaatataat atatattcaa taattgtttt ttcagacaaa gctacactaa aaaatgtaat
   109141 gataagtgga aataatatta tagttataaa tgaaagtgag atattaagta caataagtaa
   109201 atgtaaagat gtgactattg ataaagaaga aataaaaatt atcagagata aaatttttga
   109261 ttgtatgaaa accactaatc aaaatactag agagcatgtt agaaatttaa aaaatattac
   109321 tgaagaggat aagtgcccta gatgtcaaat tggacatttg attaaaagaa aaggtcagta
   109381 tggtgaattt tggggatgta gtcagtatcc aaaatgtaaa tacactagaa aataaaaaac
   109441 aacctcttaa attcgatttt aaggctttgt aaaaattaat gcttataatt aatcctgttc
   109501 ggaaaatcga ttgcttaaaa tggaaaatat ataaaaataa tagcgtgata gtgtaaggca
   109561 tagaattgtg tattctatgt cttatttctt tataattaag taatttcaat aattatataa
   109621 ataaaagaat taaaaaagtc agttgaaagt cagctaaaat gactattttt tgcctcctct
   109681 gtatggtata ataagtatat gaattttcat aggagggata accatgaacg cttttataag
   109741 aaaaagaaat aaaaattatg tagtgtactt agaatttaga gatgatgaat caggaaaaag
   109801 aaaacaaaaa aatatgggag catttgataa aaaaagagat gctaataaaa gattggctga
   109861 agttaaggac agtatatata aagatagttt tcttgtccca aatgaaatca ctctagctgg
   109921 atttctatta gactttcttg aaaaatataa agataatatt tcggcatcta catataaaag
   109981 ctatattgct atttgtaaaa atcatattaa tccttctatt ggaaaatatc gtcttcaaga
   110041 gttgagaaat attcatatac agaattatat agatgattta gctggtaact taaaccctca
   110101 aactattaaa gtacatataa atgtattgag acttgcaata aagagagcgt atagaattaa
   110161 gttaataaaa gaaaatatta tagatggaat agagagtcca agaattaaaa aatttaaaaa
   110221 tgaaatttat gataaagagc atatgttaaa attattagaa gtagctaaag gaactaatct
   110281 tgagcttcct attagtttgg ctataggtct aggattgaga ctttcagaag ttttgggatt
   110341 aacttgggat aatattgatt ttgatgaaaa tacaataaca gtaaataaga taactagtag
   110401 attagatggt tctgttatac ttaaagagcc aaagacagaa agctctgtta gaaaaatatt
   110461 tgcaccaata gagcttatga atttactaaa aaattatagg ctggagcaga ataagaagtt
   110521 attgagaagt attgttagaa atgaatataa cttactattt tttgatagaa aagggaatcc
   110581 aattgctgaa gatgtaatga gtaagaaatt tagaaaattc ttagagaata atgacttgcc
   110641 tcatattaga tttcatgact taagacattc gcacgttact ttacttataa attctaaagt
   110701 acctataaaa gttatatctg aaagggtagg acattcaaat attaatacta ctcttaatgt
   110761 atattctcat gtacttaaag aaatggacaa agaagcttct gatagaatat ctgaaaactt
   110821 atttaaggct aattaataat tattatcaat aaatacaaaa ttaataataa aagcaaaggt
   110881 ataaacataa aggggaattt ttacaaagcc ttagaatggc atatagagcg tcagatttta
   110941 gaagatatta aaattttata tttccaatat ttatgatata ataaacatag caaggaataa
   111001 atatttgaaa aaagctgtga gtggtgtttc catagaaatt tcctcacttt cttatgaaag
   111061 gaggtgaaaa ctatggaaaa tctaatgatg agtattatag ctggtgttat agctagttat
   111121 atctacgata aattaaaatg ccactctgag cgaccaacta agagtggctg ggaacttaat
   111181 attaagttcc ataaaaacaa acattaataa ctaattaatg gaaacatcac tcaaagttaa
   111241 gtaaaatatg tttccttgct tttattatac cacaaattaa gaatattaaa acaaaatttt
   111301 gtaaatacat acttaattat caatttaatc atttggaaaa aattggattt gattgtatga
   111361 aattattgct gtaatattta aattaaataa acaaatgatg ggagagataa ttatgtattt
   111421 aagaaaatta tcaaagtcag aattaattgt aatgaaattt atatggaatt tagatacaaa
   111481 agtaaaatca tatcaaatca ttaattatat gaaagaaaaa tatagttggt cagaaaaaac
   111541 aacattaaaa actttatcta agttatcaaa taaaaggttc atatatgttc aagaaacaag
   111601 tcaatgtaca tactatacaa tttcaattaa agaagataag tatcatgaat ttatatcaca
   111661 aaaaatacat aagctcttag ggtgcaattc tataaaaagc cttttagcat cattgtttca
   111721 agaagaatta acagatgaaa aaataacttc attggaagaa tgggtaaaaa actgggaaga
   111781 agaggaataa agataatata tactattcct taaaaatcta tttaaagaat aattgaaatt
   111841 ttgattttaa tataatttct ttaatcaact ctaacataca aaaataagac tcttttcaat
   111901 attaactaaa gagccttatt ttataattga ttatatttta gttaactttt gtgtatcaaa
   111961 actatactca tatacttcta atgtttcaga atttacaatt agagttccta ctgttttaat
   112021 gctatcttct ttatcagtat aagtatcaga accatcagtg ctagattcat cttgtttaac
   112081 atttttaaca ctgattattt caaactcata gtgtggaaaa tctatatttt cagctttttt
   112141 atatcttgag ttaccataat tatatgtata acaatattca tgtgcttttg aaccttttgc
   112201 tttatatata gcatctaaag cttttgagat gtcacttctt ttagtattac cagttaacat
   112261 ataatctgga gttaagcatt ggtctaaaat ttcatttttt atatcaccta ttattattgg
   112321 gaaattagca ctagtaacta atgatttgtc attagtttca tttactaaaa atacaggata
   112381 ttctttgtgt attgtagaag ataatagtgc atctattaaa ttatcagaac ttacaataca
   112441 tatttgattt ggatgtttta attcatcttt ataaaaatgc ttaattattt tttcattagt
   112501 gtcaagtcta tcaacaccac caattctagt tgcttttgta ctgttcacta aagagtcgtt
   112561 tattgatgct gttcctccaa tagcatatgt ttttacccca tctgttttaa atggtatatt
   112621 ctttccattt gttaatacaa ctggattttt atatttagca gcaactggag atatacttat
   112681 agaatcagct tctccttgat aagcatttgt aaaatatact tcatcaacct tttttagatt
   112741 gcttatttct tttgcaacat tataacttgt gtctattctg tcttttcctt ctatcctaat
   112801 aacctttatt tttttgtttt ttagtatatt ttctacattt ttgcttatag aattaactcc
   112861 acctattaaa tagatttttt taaatttatc taatctttta agagtagaat ttggtataga
   112921 attttgttta gtaagtaata ttggcgagtt agaagctcca gctaaaccac tagcactcaa
   112981 cccatctgca agacttttat ctgtgtttat aattattgct tgggtgtatt ttcttctgtc
   113041 tgctattaaa cctgctgttt catacttatt tgctccttgt attctatgag ctggaggtct
   113101 aaattttagt tctttagctg aaactaataa tgtgctagac atgacaatag aagatattat
   113161 agctaaggtt aatgcttttc ttttgaattt catattgtaa aatcctccca tccttttata
   113221 ctatgaatga tagtgtatat tattttagtt gtcaactctc tatgtatatt ttcttatata
   113281 tataagaata aattgtatta attatatcgt tacgaaaact ttttgtatat aataaaagtt
   113341 cacttcttta tttattctta taacaatcct ctaaagaact aattaagctt tctatagaat
   113401 tagaatgtac ttcttctaaa aatctctttg tttcaaatat tttatattct tcttttgtaa
   113461 taagtattgt ataatgtgta attcttttta tcctctcaga atctaaaaaa cgtttaatag
   113521 tgagtcttga aagaagagtt agtgtagttg tcgccttcca gttatattct gattccatag
   113581 cttccataac ttcttttgat gttactatat cattcttatt ccatatgaat ttcataactt
   113641 ttaattcagc ttgtggtatt ttttgcatgg atatgtacat tcctttctgc aattaaaata
   113701 tcaacatata tagacgttaa aataataaaa tatatgttat aagtatatat taacataaag
   113761 taaaagaaga tgtctcaatc ttaagacatc ttctttatta aatttttatt cttcaaattt
   113821 tcgatactca attatttctt ttatcaatct aattatcgct ttttgttctt ttactgttaa
   113881 actatcaatt aactcatagg cttcagacga aagagtttca acatcatttt cattctgtat
   113941 aatattttca aataaaactt ctaaaggtat ctctaatgca tttgcaattt taaaaattga
   114001 acgaagtgat gctttacttt cacctctttc aatttgacca atataagcag gaaacaaacc
   114061 agccttcttt gctaatgtat tttgattata ccctgctttt cttctataat ttcttattct
   114121 tttaccaatt acattatata tttcatcttc taacattttt atcattcctt attagattat
   114181 attagtttat ttatcttaat gatatgttat acatgtcaaa aatatactta tataacatgt
   114241 aatattatta aatatatatt atataagtat gtatatattt aataagaagc tattgtagac
   114301 aaaaaaataa agccctttaa agaaaactca tttaagagta atccttaaag ggcttattat
   114361 ttatctatct ctttttctta ccttttttac gacttttaca tgccatgata tcacttcctt
   114421 tctactttat atctatttat aaacctatca tatctttaga cttagaaatt ttgcctttgt
   114481 cttcttttat ataaatctta gttgtatcag tggattcgtg attgaggata gttgatatat
   114541 cttcaagtgg taaattattc gctttagcta tagttgcaaa acttcttctt aatgaatggg
   114601 gagctaagtt atctatatct attaatttac cagctttctt agcccaactt cttaatacat
   114661 tagatgtagc cttatgatat tctttatcat atttaactaa gaaaacataa tcatttacta
   114721 tatcttcttt ttttctaact tctttaagct ttagtaataa atcttttact ttctcactaa
   114781 aataaaaatc tactattttc ccaccttttt ctttaatatt ttcacatact ctattatcaa
   114841 agtctatatt atcccatctt aaattacttg tggctgtaac tctaccagca gttgatagag
   114901 caaaatttat ataaacctct aattgtaaat catctcgttt tgataactta tcttgtagct
   114961 ctttagcctg ttctatattc aagaaatgtt tttccacaac aggtaaaccc tttttaggtc
   115021 tttcgattag agatactgga ttctctgtaa caattctctt ccttctaaga tggtcatata
   115081 gagatgaaat gcctgaaaat attactttta ttctattaac atgattgtcc tccatcctaa
   115141 atgaaatata ttccattata tcgtcttcag tacaatcttc gattaataaa tcctccattt
   115201 catcatgcag atatttagcc caagtatata agtcacattt atatacatat atagtttttt
   115261 cacttaaacc agctattttc ttagcttgaa gaaatccttt aattaacttt tcattatttt
   115321 tatttatgtt gccttctatc ttaattcttt tacttctttt ttcaaatgtt gccaaatact
   115381 tcacttcctt ataaaaaaga ctagagaaat taatctctag tctctaattt atctttaatt
   115441 tttgttatgt ctgtttcaac tctttcaagt ctgctgttat tagtatttaa tgcttcagca
   115501 aatttatcta atttatcatc aaacttatct attgtattac caaataaagt tctctgctct
   115561 ttaatttctc ttgaaaaata agctctttct ttttttctat catcttgttc tagttgtcta
   115621 ttcttttcta aatattttcc aagccataac atcaatacca ttaaaagtat ggctgtatac
   115681 ccatactgac ttaataattc aaccatttct ttagataaca tctacttttc ctttctgttc
   115741 tgtacttgta tttgatttat ccctatagat gctccccaac acaaaatacc ttcaaagaca
   115801 gcttctattg acagctcttt cataaacaaa caactgctta tcattgctat aactaacaag
   115861 ataaaaggta tgtatttatt tttaatatta gattctttta taaatgttcc taatatgtaa
   115921 agcccaccta ttaacattat taaattttca ggtataaatt gcattatatc catgtgattt
   115981 cctcctatcc aagaatctca tttaattctt ttactttagt ttttatttgc tctaatttta
   116041 catcattgtt ttctaccttc attgaactta tcttattaca tatatttatt atgcttttgc
   116101 cataattcat atctggacac catttgcctg ataaactttc tactgtttta gcttctccat
   116161 gtaaatatgg aaaatgtcta gggtctaatg tagttccatt tactttatat tcaactttac
   116221 caactaattc actatatttt ggatatccct tagctccagc atataatgct agatggtcaa
   116281 taaatgctga tactccatcc tcccaacaat taaatcttgt atgagctgtt gggtctaaat
   116341 ctcctccacc tttatttcct ttaagaccac acatattgca ataagaagga tttaaaactc
   116401 taccaaaatt aaaatatcca gtttctacaa atgcttgagc aattgcaata actggattta
   116461 cacctttttt ctctgcttct ttatatataa ttggtactat agctccgcat aaaaaatgtg
   116521 gtggattaga gttatttttt aatgtatcta aatacgaaaa gacttgttct agtgtagctg
   116581 ttgatttatc taatatattc aattcattac ctcctacttg cctataaaat ctaacacttt
   116641 atgaagtgta gcccatctat catcaccttg taacttagtg aatctctcgc tagttttaat
   116701 tttactggat gctccaccaa ttacatatag gttttcacaa tgtccaggaa cataattttc
   116761 caaatcacat acagagactt cattagtctt ataattcatg gccattaatt gggctataac
   116821 tttatctacc tcaccctcat aaactattgc atatttcact ttgttatctt gtggtttacc
   116881 agctacagac ttattaaata ttccttcgta aatgtctatg gccatatctt tagcattata
   116941 ttttttagtg tcagatgtgt ctacaaagca gcactcgact aaaattgact ttgccttcgt
   117001 tcttcttaaa aatgctagag ttttcttttc tttaactcca cgatttttaa aatctttatc
   117061 accttttgca tgataagttt cagttatttt tttacatatt cttgatgcta tttcaacagt
   117121 ttctttgtca tttaaattat aaactaaaac ttctactcct cgaccaccac cactgttgaa
   117181 atggatactt acatttagat cagtattata tgaattacat ttagctataa ttttattcaa
   117241 tatatcactt tgagaagttc cattgttaca agtacagtca taaactttac attccttttg
   117301 agctaaaggt aataactctt ttagtacatt tcttgcttct gtagattcct ttatatttcc
   117361 tattgctcca gaacctatct tattatctgg attatgtcct gcatgaattg ttaatgtttt
   117421 tatattcaaa attaccactc cttttaatta aaagagaatt gaaattaatc aatcctctaa
   117481 aattgacata aaaaaaacct ttatacttta gataataggt tctactagtg tatcttcttt
   117541 atttaataaa tttgttaact ctgtgtattc actttccttt atcctgttca tagcgtaaaa
   117601 tacatctaac ttagtctgca attcttctct agtttcataa ttcttttgtt caatcattct
   117661 ttttaaaata ttatacatgt tgtttcctcc attttttata gttttataac acgttatttg
   117721 tgttaagttc taacatagca attctataag cattatctac taataaactg tcttgttgct
   117781 tttgattttc tattaaaatt gtaattttat ccgcatttat ttcttctata cttggctctg
   117841 atttaggtgg attattttgt aattctaacc actcattata aacctgttct cctgttttaa
   117901 ttagctctcc gttttttatc actggagtaa atattttttt accatctgca ataaagtaat
   117961 tatctatatt atttaaatca ttctcaaatc catattctat taaaatttct attttctttt
   118021 ctatatccat cttatttttc ctttctaaat taaatagttt acatataaat acaaccaact
   118081 acgataagtt atatcattat aatatatctc aatttctcca tttgtacgaa tgattccgtt
   118141 ataatacttt ccatctgttg tttgaaatat tactattatg tttttacgag gtgcatattt
   118201 tgaaggtatc tttccaatga tagtacctgc cgttgtaaca cctccattaa tagttgcatt
   118261 aattgttaca aagttattat ttgtgcaata gtttccaaca gaactagcat atccaagata
   118321 tggctgccac ccattaagaa agtttattga aaatggaaaa tcaattctaa cattgtaatt
   118381 ttttatatta tttctgataa cttctatatg acttcctaaa ttttgtgtac tttcaaaact
   118441 aatgtctggt atcacaatac ctgtgttgca aataaattta gtttgattat tatattgttc
   118501 taaatttagt gatgttaatt caatttcttg tggttttgaa agttgataga taatagttat
   118561 tggattattt tttatccatt cactaaaccc atttccatct tgtgtagtaa gtttactttt
   118621 taatatttta aatgctatat caccactacc agtagttgag catccctcta tgtcattatt
   118681 gttaaaatca tttctacttt ttccatttaa attattgcat aaaacatatg ctatgtctaa
   118741 actatctaca acagcttgag gagttaatgt tcccataaat tgcagagtat tatcatatac
   118801 atgtgataaa ttaagatttc caatatcagt ataagtatgt tcctcacatc tttttattaa
   118861 gtaatattta tcatttttat aaactatttc atcttttatt ccatttggta aacttcttaa
   118921 tgtatatgga attgtctttt tatcatattt atttccttta gttataattg ttttattccc
   118981 attatcatgt aaatctttta ttatagtaac tcttagatac tttgcatttt tagggcttct
   119041 agcaatataa aaaatatctt tatctcctat tattctttcg tttaatgatg ctgttataaa
   119101 acttttattt atatcatacc aacaaatatt tctactacaa ttataaaaag tatactctgt
   119161 atctggttct atttctatat agtctagggt atatttatga ttactagctt cagaaataag
   119221 ttcctctcca ctaagatatt gtaaaatata attatcttta aaatcggcat tcttattaaa
   119281 gatattaatt ccactatatt gataacttaa aaattctatt ttatctcttt gcccaacact
   119341 taatagttca ttagagtaat ctatattaat atctgtataa tctccttcta atatggtaat
   119401 tttcaaactt atttcataac cagatgtaag tgtatcgtta tctaaaacac tccttaaaac
   119461 aacattacaa tcatttaagt ctgatattgt tgtaaatgta tatttaaatt taccaattac
   119521 tcctcctggt atagctatat ttgtcagatt aggaataaat actgaatttt cttcgcctaa
   119581 gctatgaata tatattccac ttgtactcgg taaagtgttt ttatcaacat caactatgat
   119641 tgtatatatg gtatctggtt tatatgaagt gtaattgatt gtaaaaaaat tagaatatct
   119701 tatatcattt tctgttagta tatttatttt tccatccaca aaagttgctt tccataaaga
   119761 aaaatctgaa ctagtttttc cccataaatc aattaatgtc tttccttcta cattaaaatt
   119821 agttaaatag ccctttttac tattttctat agtatattct cctgtatcag tactacattt
   119881 tatattgtca acctccttga gattttctat atcattgacc tttttaagta aatctttata
   119941 tatcaaatta aaacacctct cttcacaaaa cccctatttt gtagtttcta ctctttctac
   120001 tactccactt tctttaatta tacaatcttc tactgctttt ctataatcct cgttagttac
   120061 atcatctaat tcaaaaggtc tattttttaa aggattcaat cctctactta aaatcctctc
   120121 tgctaatatt cttactacaa cattatttat attcattata atagccctcc tactttttca
   120181 ttttcattta gtaatatttg attttctaac tcttgtattc tcttttcttc ttcgcttaaa
   120241 tagattggaa tatcttttaa aataggttct tttgttattg gatttataga ttctatatac
   120301 tgtttactat agtctatatt tccatattca acatcaatat aatgtaattc tgttattgta
   120361 tcatgctcta atatatctcc tgttgcttct cctgtttgga gtaatatttt accagtttgg
   120421 tcgtaaatta ttctatttgc tctattcatt ttatcacctc atttatttaa attttatcgc
   120481 atgccattta tatgctctaa aatcatttag agtgcttagt gaaggtactc taactccatt
   120541 attatccatg gaaacatgtc ttttgccaag ggtatataaa gctcctcgta atttaaaaga
   120601 ttcatcacca tattccttgt taaaagcaat attaactaca aacccagtat tattagaaat
   120661 gggaaaagta tttttaattg caaaaacaaa atacttataa aaagcattcg aatgtggttc
   120721 atattcacat tcagcaaaaa atatatcagg aataaatcca attccattta aatcaagcca
   120781 ataagggctc gtttctgtaa cagtatgaga agtattaggg tcatatacac atgcaattaa
   120841 ggatgaattt tctctagcat aagcagttcc tgttgcatat ttatacttag aatttaactg
   120901 tgatatagta ttattagctt gtgttaactg gttcatcaaa tcctgcacac tagcgtctga
   120961 actatcaaaa cttgttttta ttttctctga caactcaaca agtgtattat ttaaacttgc
   121021 ttctatattc tttaatgcta aagtatttat aatacttgtt ttcccaactt taaatcctgc
   121081 attaacctca actaattttg ttgatatatc atttaaattt acattttcgg gtagtggcat
   121141 tatattctta cttatactta atactttttc tgctgtagta ttattactgt ctgtaacaac
   121201 tattttaagt atgtgtagtg cattatcttc taatgtgtag ttaattgttt tctctgttgt
   121261 taaatctgtt gttatagttt cttttagtat atcatctata aagtattcta ttttagttaa
   121321 ta
//
LOCUS       DAYAKB010000002       100519 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.002, whole genome shotgun sequence.
ACCESSION   DAYAKB010000002 DAYAKB010000000
VERSION     DAYAKB010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 100519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100519
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.002"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            439..2109
                     /gene="pdcB"
                     /locus_tag="ACGI3L_000167"
     CDS             439..2109
                     /gene="pdcB"
                     /locus_tag="ACGI3L_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase PdcB"
                     /protein_id="HFG9195906.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2231..2965)
                     /gene="pflA"
                     /locus_tag="ACGI3L_000168"
     CDS             complement(2231..2965)
                     /gene="pflA"
                     /locus_tag="ACGI3L_000168"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFG9195907.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNIDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3125..5356)
                     /gene="pflB"
                     /locus_tag="ACGI3L_000169"
     CDS             complement(3125..5356)
                     /gene="pflB"
                     /locus_tag="ACGI3L_000169"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFG9195908.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            5715..6710
                     /locus_tag="ACGI3L_000170"
     CDS             5715..6710
                     /locus_tag="ACGI3L_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HFG9195909.1"
                     /translation="MFITVVLFLVGFLLITKGADIFINCTVEIGKKTNISEIILGATI
                     VSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICNTGLALGLVVFISPFNVDKKMFF
                     SKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIFYMVNNYRSVVGKSDTKNRNIKN
                     NTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMMIIGSQILIESGVIIASFLNIPQ
                     GIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNILGANILNIVSVIAVSAIPNNIP
                     ILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGILMLFTYFLYISILYFMYII"
     gene            6801..8414
                     /locus_tag="ACGI3L_000171"
     CDS             6801..8414
                     /locus_tag="ACGI3L_000171"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9195910.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            8689..10674
                     /locus_tag="ACGI3L_000172"
     CDS             8689..10674
                     /locus_tag="ACGI3L_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9195911.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            10679..11113
                     /locus_tag="ACGI3L_000173"
     CDS             10679..11113
                     /locus_tag="ACGI3L_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFG9195912.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKNLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11142..11702
                     /locus_tag="ACGI3L_000174"
     CDS             11142..11702
                     /locus_tag="ACGI3L_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFG9195913.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            11766..12266
                     /locus_tag="ACGI3L_000175"
                     /pseudo
     CDS             11766..12266
                     /locus_tag="ACGI3L_000175"
                     /inference="COORDINATES: protein motif:HMM:NF015569.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIB"
     gene            12306..12725
                     /locus_tag="ACGI3L_000176"
     CDS             12306..12725
                     /locus_tag="ACGI3L_000176"
                     /inference="COORDINATES: protein motif:HMM:NF019286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIB"
                     /protein_id="HFG9195914.1"
                     /translation="MAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFP
                     LLSPFLGPGAVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAE
                     AEPDTVQVGVPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            12766..13131
                     /locus_tag="ACGI3L_000177"
     CDS             12766..13131
                     /locus_tag="ACGI3L_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFG9195915.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13232..14005
                     /gene="srlD"
                     /locus_tag="ACGI3L_000178"
     CDS             13232..14005
                     /gene="srlD"
                     /locus_tag="ACGI3L_000178"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HFG9195916.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14354..16498
                     /locus_tag="ACGI3L_000179"
     CDS             14354..16498
                     /locus_tag="ACGI3L_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HFG9195917.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            16586..16921
                     /gene="spoIIAA"
                     /locus_tag="ACGI3L_000180"
     CDS             16586..16921
                     /gene="spoIIAA"
                     /locus_tag="ACGI3L_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045152 - antisigma factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HFG9195918.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            16935..17363
                     /gene="spoIIAB"
                     /locus_tag="ACGI3L_000181"
     CDS             16935..17363
                     /gene="spoIIAB"
                     /locus_tag="ACGI3L_000181"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA];
                     GO_process: GO:0042174 - negative regulation of
                     sporulation resulting in formation of a cellular spore
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HFG9195919.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            17386..18150
                     /gene="sigF"
                     /locus_tag="ACGI3L_000182"
     CDS             17386..18150
                     /gene="sigF"
                     /locus_tag="ACGI3L_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HFG9195920.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAIKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            18430..18867
                     /gene="spoVAC"
                     /locus_tag="ACGI3L_000183"
     CDS             18430..18867
                     /gene="spoVAC"
                     /locus_tag="ACGI3L_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HFG9195921.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            19034..20047
                     /gene="spoVAD"
                     /locus_tag="ACGI3L_000184"
     CDS             19034..20047
                     /gene="spoVAD"
                     /locus_tag="ACGI3L_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HFG9195922.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            20061..20423
                     /gene="spoVAE"
                     /locus_tag="ACGI3L_000185"
     CDS             20061..20423
                     /gene="spoVAE"
                     /locus_tag="ACGI3L_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HFG9195923.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            20606..21622
                     /locus_tag="ACGI3L_000186"
     CDS             20606..21622
                     /locus_tag="ACGI3L_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9195924.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            21997..22839
                     /locus_tag="ACGI3L_000187"
     CDS             21997..22839
                     /locus_tag="ACGI3L_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HFG9195925.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            22854..23318
                     /locus_tag="ACGI3L_000188"
     CDS             22854..23318
                     /locus_tag="ACGI3L_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195926.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            23332..24477
                     /locus_tag="ACGI3L_000189"
     CDS             23332..24477
                     /locus_tag="ACGI3L_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9195927.1"
                     /translation="MNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPELAFEEYKSQ
                     KALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPGMGHACGHNI
                     IGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFNNVDAALILH
                     PSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSVNSMRLHLKD
                     YARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKGAAISTGTNV
                     EIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGNLTHEIPAIQ
                     AYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            24521..25456
                     /locus_tag="ACGI3L_000190"
     CDS             24521..25456
                     /locus_tag="ACGI3L_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HFG9195928.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(25730..28423)
                     /locus_tag="ACGI3L_000191"
     CDS             complement(25730..28423)
                     /locus_tag="ACGI3L_000191"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFG9195929.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDGGGNNGGGSTTPPDGGGTPAT"
     gene            28637..29335
                     /gene="yunB"
                     /locus_tag="ACGI3L_000192"
     CDS             28637..29335
                     /gene="yunB"
                     /locus_tag="ACGI3L_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HFG9195930.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(29547..30554)
                     /locus_tag="ACGI3L_000193"
     CDS             complement(29547..30554)
                     /locus_tag="ACGI3L_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HFG9195931.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            30782..31666
                     /locus_tag="ACGI3L_000194"
     CDS             30782..31666
                     /locus_tag="ACGI3L_000194"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9195932.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            31868..33418
                     /locus_tag="ACGI3L_000195"
     CDS             31868..33418
                     /locus_tag="ACGI3L_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9195933.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            33447..34094
                     /locus_tag="ACGI3L_000196"
     CDS             33447..34094
                     /locus_tag="ACGI3L_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFG9195934.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(34236..34496)
                     /locus_tag="ACGI3L_000197"
     CDS             complement(34236..34496)
                     /locus_tag="ACGI3L_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HFG9195935.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFRYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            34713..35996
                     /gene="hflX"
                     /locus_tag="ACGI3L_000198"
     CDS             34713..35996
                     /gene="hflX"
                     /locus_tag="ACGI3L_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFG9195936.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYANLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDADLDEEDFNIYREYILEK"
     gene            36004..36681
                     /locus_tag="ACGI3L_000199"
     CDS             36004..36681
                     /locus_tag="ACGI3L_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HFG9195937.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            36767..37210
                     /locus_tag="ACGI3L_000200"
     CDS             36767..37210
                     /locus_tag="ACGI3L_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9195938.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            37515..38159
                     /locus_tag="ACGI3L_000201"
     CDS             37515..38159
                     /locus_tag="ACGI3L_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFG9195939.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(38245..38622)
                     /locus_tag="ACGI3L_000202"
     CDS             complement(38245..38622)
                     /locus_tag="ACGI3L_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFG9195940.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(38622..39008)
                     /locus_tag="ACGI3L_000203"
     CDS             complement(38622..39008)
                     /locus_tag="ACGI3L_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFG9195941.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            39187..39942
                     /gene="nadE"
                     /locus_tag="ACGI3L_000204"
     CDS             39187..39942
                     /gene="nadE"
                     /locus_tag="ACGI3L_000204"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HFG9195942.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            40025..40744
                     /locus_tag="ACGI3L_000205"
     CDS             40025..40744
                     /locus_tag="ACGI3L_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9195943.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(40911..41915)
                     /locus_tag="ACGI3L_000206"
     CDS             complement(40911..41915)
                     /locus_tag="ACGI3L_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFG9195944.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            42181..43077
                     /locus_tag="ACGI3L_000207"
     CDS             42181..43077
                     /locus_tag="ACGI3L_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HFG9195945.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            43198..44460
                     /locus_tag="ACGI3L_000208"
     CDS             43198..44460
                     /locus_tag="ACGI3L_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFG9195946.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            44536..45729
                     /locus_tag="ACGI3L_000209"
     CDS             44536..45729
                     /locus_tag="ACGI3L_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HFG9195947.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            46358..47152
                     /locus_tag="ACGI3L_000210"
     CDS             46358..47152
                     /locus_tag="ACGI3L_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HFG9195948.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDVAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            47247..48587
                     /locus_tag="ACGI3L_000211"
     CDS             47247..48587
                     /locus_tag="ACGI3L_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFG9195949.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            48724..49956
                     /locus_tag="ACGI3L_000212"
     CDS             48724..49956
                     /locus_tag="ACGI3L_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HFG9195950.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     TLIESGIVTMNKEACEIC"
     gene            49996..51138
                     /gene="acrC"
                     /locus_tag="ACGI3L_000213"
     CDS             49996..51138
                     /gene="acrC"
                     /locus_tag="ACGI3L_000213"
                     /EC_number="1.3.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0043958 - acryloyl-CoA reductase (NADH)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acryloyl-CoA reductase"
                     /protein_id="HFG9195951.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            51149..51943
                     /locus_tag="ACGI3L_000214"
     CDS             51149..51943
                     /locus_tag="ACGI3L_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HFG9195952.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            51957..52976
                     /locus_tag="ACGI3L_000215"
     CDS             51957..52976
                     /locus_tag="ACGI3L_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFG9195953.1"
                     /translation="MRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLAD
                     QLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKK
                     PEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATI
                     VCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVN
                     LTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTT
                     VRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEMI
                     ESLNR"
     gene            53075..54451
                     /locus_tag="ACGI3L_000216"
     CDS             53075..54451
                     /locus_tag="ACGI3L_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HFG9195954.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(54783..55127)
                     /locus_tag="ACGI3L_000217"
     CDS             complement(54783..55127)
                     /locus_tag="ACGI3L_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195955.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            55615..56625
                     /locus_tag="ACGI3L_000218"
     CDS             55615..56625
                     /locus_tag="ACGI3L_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HFG9195956.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            56761..57249
                     /locus_tag="ACGI3L_000219"
     CDS             56761..57249
                     /locus_tag="ACGI3L_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HFG9195957.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            57425..59353
                     /locus_tag="ACGI3L_000220"
     CDS             57425..59353
                     /locus_tag="ACGI3L_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9195958.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            59530..59940
                     /locus_tag="ACGI3L_000221"
     CDS             59530..59940
                     /locus_tag="ACGI3L_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFG9195959.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            59962..60264
                     /locus_tag="ACGI3L_000222"
     CDS             59962..60264
                     /locus_tag="ACGI3L_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HFG9195960.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(60481..61173)
                     /locus_tag="ACGI3L_000223"
     CDS             complement(60481..61173)
                     /locus_tag="ACGI3L_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HFG9195961.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(61199..62386)
                     /locus_tag="ACGI3L_000224"
     CDS             complement(61199..62386)
                     /locus_tag="ACGI3L_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9195962.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            62722..64599
                     /locus_tag="ACGI3L_000225"
     CDS             62722..64599
                     /locus_tag="ACGI3L_000225"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9195963.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            64956..66362
                     /locus_tag="ACGI3L_000226"
     CDS             64956..66362
                     /locus_tag="ACGI3L_000226"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9195964.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            66390..67238
                     /locus_tag="ACGI3L_000227"
     CDS             66390..67238
                     /locus_tag="ACGI3L_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9195965.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            67899..68591
                     /locus_tag="ACGI3L_000228"
     CDS             67899..68591
                     /locus_tag="ACGI3L_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9195966.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            68588..69523
                     /locus_tag="ACGI3L_000229"
     CDS             68588..69523
                     /locus_tag="ACGI3L_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9195967.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            69671..70594
                     /locus_tag="ACGI3L_000230"
     CDS             69671..70594
                     /locus_tag="ACGI3L_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9195968.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            70578..71348
                     /locus_tag="ACGI3L_000231"
     CDS             70578..71348
                     /locus_tag="ACGI3L_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9195969.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            71358..72140
                     /locus_tag="ACGI3L_000232"
     CDS             71358..72140
                     /locus_tag="ACGI3L_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9195970.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            72517..73053
                     /gene="rbr"
                     /locus_tag="ACGI3L_000233"
     CDS             72517..73053
                     /gene="rbr"
                     /locus_tag="ACGI3L_000233"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HFG9195971.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            73085..73474
                     /locus_tag="ACGI3L_000234"
     CDS             73085..73474
                     /locus_tag="ACGI3L_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HFG9195972.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            73511..73897
                     /locus_tag="ACGI3L_000235"
     CDS             73511..73897
                     /locus_tag="ACGI3L_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HFG9195973.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            74024..75466
                     /locus_tag="ACGI3L_000236"
     CDS             74024..75466
                     /locus_tag="ACGI3L_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HFG9195974.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            75763..76578
                     /locus_tag="ACGI3L_000237"
     CDS             75763..76578
                     /locus_tag="ACGI3L_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9195975.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            77180..78364
                     /locus_tag="ACGI3L_000238"
     CDS             77180..78364
                     /locus_tag="ACGI3L_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195976.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(78741..79868)
                     /locus_tag="ACGI3L_000239"
     CDS             complement(78741..79868)
                     /locus_tag="ACGI3L_000239"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9195977.1"
                     /translation="MKGKITMDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEG
                     KDVIAEAQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESK
                     DVSILAAYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQ
                     MLLMGFKNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLN
                     NIKQEVVETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLH
                     SDIAQSKRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIG
                     RTGRAGEEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            80313..81506
                     /gene="nifV"
                     /locus_tag="ACGI3L_000240"
     CDS             80313..81506
                     /gene="nifV"
                     /locus_tag="ACGI3L_000240"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004410 - homocitrate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HFG9195978.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            81531..83456
                     /locus_tag="ACGI3L_000241"
     CDS             81531..83456
                     /locus_tag="ACGI3L_000241"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HFG9195979.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            83478..84473
                     /locus_tag="ACGI3L_000242"
     CDS             83478..84473
                     /locus_tag="ACGI3L_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HFG9195980.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            84798..85271
                     /locus_tag="ACGI3L_000243"
     CDS             84798..85271
                     /locus_tag="ACGI3L_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9195981.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            85305..85799
                     /locus_tag="ACGI3L_000244"
     CDS             85305..85799
                     /locus_tag="ACGI3L_000244"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9195982.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            85896..86417
                     /locus_tag="ACGI3L_000245"
     CDS             85896..86417
                     /locus_tag="ACGI3L_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9195983.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            86606..86917
                     /locus_tag="ACGI3L_000246"
     CDS             86606..86917
                     /locus_tag="ACGI3L_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9195984.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            86945..87631
                     /locus_tag="ACGI3L_000247"
     CDS             86945..87631
                     /locus_tag="ACGI3L_000247"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HFG9195985.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            87863..88747
                     /locus_tag="ACGI3L_000248"
     CDS             87863..88747
                     /locus_tag="ACGI3L_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFG9195986.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            88846..90021
                     /locus_tag="ACGI3L_000249"
     CDS             88846..90021
                     /locus_tag="ACGI3L_000249"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HFG9195987.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            90149..91003
                     /locus_tag="ACGI3L_000250"
     CDS             90149..91003
                     /locus_tag="ACGI3L_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9195988.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            91047..92282
                     /locus_tag="ACGI3L_000251"
     CDS             91047..92282
                     /locus_tag="ACGI3L_000251"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFG9195989.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            92383..93324
                     /locus_tag="ACGI3L_000252"
     CDS             92383..93324
                     /locus_tag="ACGI3L_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HFG9195990.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(93543..93896)
                     /locus_tag="ACGI3L_000253"
     CDS             complement(93543..93896)
                     /locus_tag="ACGI3L_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFG9195991.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            94192..95103
                     /locus_tag="ACGI3L_000254"
     CDS             94192..95103
                     /locus_tag="ACGI3L_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HFG9195992.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            95363..95797
                     /locus_tag="ACGI3L_000255"
     CDS             95363..95797
                     /locus_tag="ACGI3L_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6323 family protein"
                     /protein_id="HFG9195993.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            95820..97355
                     /locus_tag="ACGI3L_000256"
     CDS             95820..97355
                     /locus_tag="ACGI3L_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6179 domain-containing protein"
                     /protein_id="HFG9195994.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGMTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            97439..98806
                     /locus_tag="ACGI3L_000257"
     CDS             97439..98806
                     /locus_tag="ACGI3L_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9195995.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            98841..99065
                     /locus_tag="ACGI3L_000258"
     CDS             98841..99065
                     /locus_tag="ACGI3L_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015759013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HFG9195996.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGVTMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(99515..99913)
                     /locus_tag="ACGI3L_000259"
     CDS             complement(99515..99913)
                     /locus_tag="ACGI3L_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsmA family protein"
                     /protein_id="HFG9195997.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(99916..100359)
                     /locus_tag="ACGI3L_000260"
     CDS             complement(99916..100359)
                     /locus_tag="ACGI3L_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9195998.1"
                     /translation="MILLKSNYDCFRIAMLLKELYSKTMYTVEENFKENGLTHQQIIV
                     IKLIAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTT
                     GFEFATNFKIKMQESFDDIFKNCDENELSDLVKNLRNILAKVKER"
BASE COUNT        38121 a        11456 c        18098 g        32844 t
ORIGIN      
        1 ttatagatga tgaagaaata tcaaaatctt atattatagg aagagacact tctttgccaa
       61 aatctataga aaagcaatac caaatccaaa gagaataggc gaagaaaaaa ataaaataaa
      121 ttcaagagta atagaaaagt tttatagaat aaagaactga taactcttta tataacgaaa
      181 aatagaattt taagagaaaa tgatttaata aatgatttaa catggtgttt tagcaggtaa
      241 aaataaatca ccagtaatga ttatagaaaa attactttat gaatctcaaa aaacttagtt
      301 aagagtaaga gatttgataa gataactaaa gttggggaaa tgtgtttgat gagacaaaaa
      361 attagtaaaa tagtataatc taaataagga tattttgttg attaaactac actaatagta
      421 atattgtagg gggaaaagat gagagaagaa tcgaactctt taagtttaga ccatatagaa
      481 attttctttg aacttttatc tcaaagtaca gaagattata tatttttttg ggatataaat
      541 aggaataaat ttaaaatttc ttcagcaatt tttgatgaat ttaacttaag taaagagata
      601 gaatctgatt tggtcaattg ttggagtaaa attgtttatc cggatgatgt tcaaatatgg
      661 aaagatgata tacaagaatt actacatgga aaaaaaggtg agcacaattt agaatatagg
      721 ttgattaata aatataaaga aatagtatgg atttcttgta gaggtaaagt ttatgtgtcg
      781 gatgacccaa aaactatatt tctagtcggg agaataaaga atattggtga aaaaaataaa
      841 tttgattcta tcacaggaac gtggaataga gaacaatttg aacatagaat gaattatctt
      901 ataaaagaga aaatttataa aaatggtgct atgtttatta tggatattga taattttaaa
      961 aatataaatg aaaaatatgg acattcttat ggtgacaaag tattgcgtgc aattgctact
     1021 gaagtattag aatatcttcc aaaagatgta agattgtata ggttagatgg agatgaattt
     1081 gcattttttt accctatgtg tactaaagaa actatagaga aaatatatga aaagatacag
     1141 atgtatacaa atactcagca tgaaattgaa tcaaataagt actattgcac agtgactgca
     1201 ggcgttgcta tgtatccaga agatggagat aattatttag atttatttaa acatgctgat
     1261 attgcattgg atatagcaaa aattagtggt aaaaatagaa ttaagttttt ttcacaagag
     1321 ctctatgaaa ataaactaaa ggtaatttca atgcaacaaa aactaagaga gtgcgttgaa
     1381 aataatttta atgattttga gttgtttttt caaccccagg taaatgctgt tacaaaagag
     1441 gtaatagggg cagaggtact tttaagatgg cattcgagta cttatggaga agtatctcct
     1501 gttgaattta taccaatact agaacagagt aatttaatta taccagttgg gaagtggatt
     1561 ataaaagaag ctgtaaaaca gtgtaaagaa tggcataaaa taaatccaga ctttaaaata
     1621 tctgtaaatg tatcgtatat tcagttaaag gaagattttt ttagagattt tatagtagaa
     1681 tgtttagtag agtatcaatt aagacctgaa tttttaattt tggaattaac agagaattgt
     1741 tggataccag atataaattt actaaatgat aaatttatta gtttaaaggg tataggagta
     1801 tatattgcaa tagatgactt tggtacagga tattcatctt taaattacct taaagaactg
     1861 tctgttaata taataaaaat tgaaagaagt tttgttaaga atattacata taatagttat
     1921 gaatatactt ttcttgaata tattattaaa ttagctcata ttataaattt aaaagtttgt
     1981 gttgagggaa tagagtctta tgaagagtat gatatagtaa aaagcttagg tgtagatatt
     2041 attcagggtt ttttatttgg aagacctgta agtgcctctg aattttataa atttcagcta
     2101 tcaaagtgat gtatataaaa tgagatatat agtatataaa aatagggcaa agtggaagtt
     2161 ttgaagttta ttaaaaattt acactttacc ctattttgtt atgtcttcta taaaggatta
     2221 atatactaca ctaactatta tatactttca ctccaaattt agagattatt tcactagctt
     2281 tttggacatc ttccttagtg gcatcaggaa catcttttag ttcataatcg atacctaaac
     2341 tttcccattt gtgtattccc atagaatggt atggtagcaa ttcaaatctt tctacatttt
     2401 tcaatgtagc tacaaattga cctagttttt ctaaattatc tatatcatca gtaatgccag
     2461 gaactaaaac atgtcttatc catacaggaa tatttcttga ttctaagtgt ctagcaagtt
     2521 ttaatgcctt atccatacca acaccagtca aatcaataga tttttcctca accatatgtt
     2581 ttaaatcaag taaaaccaaa tcaatattat ctaaaactgg gtctatagtt tctatatcta
     2641 caaatccaga tgtatccaag caagtgtgta tatcattttc ttttgctttt ttaaataatt
     2701 cacttaaaaa ttctggttga agagtggatt caccaccaga ggcagttata cctccaccag
     2761 aaaacttcat aaaagaagta tacttaagag catccgttat tatttcatca actgtgtatt
     2821 cttttcctga tttaatatcc catgtatccc tgttatgaca gtatttgcat ctaagaggac
     2881 acccctgaaa aaataatata tatcttattc ctggtccatc tacagtacca aacgtttcta
     2941 tagaatgtat ctttccctta atcatagagt tcacctcaca atatatttta ataaccttat
     3001 caatagttat aatatttctc taaaaaaggc catcttatac cagaaataat tcaaatataa
     3061 gatagccttt tatttttatt ttttacacag tagtaatctt agttaaagta taaaaattta
     3121 aagactaagc cattttaccg tggaatgttc tgtttataac atctaattgt tgctctttag
     3181 ttaattttat gaagttaact gcatatccag atactcttat agttaattgt ggatattctt
     3241 ctggatgttc catagcatct tctaaagtag ctctatcaaa tacatttaca tttaagtgat
     3301 gagcattttg agcgaagtat ccatccatca ttgcagaaag attgtttatt ctttcagtca
     3361 tatcttttcc taaagcacca ggtactatag agaaagtatt agatatacca tcttgagcat
     3421 gttcatatgg taatttagca actgaagata atgaagctaa agcaccatta gtatctctac
     3481 catgcattgg gttagcacca ggagcaaatg gagcaccagc tcttctacca tctggtgtat
     3541 taccagtttt cttaccataa acaacatttg aagttattgt aagtatagat tgagttggat
     3601 aagaatttct ataagtttta ttctttctta ttttattcat aaagctttca actaactcta
     3661 cagctatact atcaactcta tcatcattat ttccgtattt tggataatct ccttctattt
     3721 caaaatcaac agctattcct tgttcatttc taatagtttt aaccttagca tgttttatag
     3781 cagataatga gtctgcacaa actgataacc cagccatacc acaagccata gttctaaata
     3841 tatctctatc atgtaatgcc atttctaatg cttcataaga atatttatca tgcatataat
     3901 gtattacatt taaagtattt acatataatg ttgctaacca atcagtgaat ggttcaaatt
     3961 tactcataac ttcatcataa tctaagtact cagaagttat aggttcaaat cttggtccaa
     4021 cttgaacacc agatttctca tctacaccac catttatagc gtataataaa gttttagcta
     4081 agttaactct agctccaaag aactgcattt gtttaccaat tctcattgca gatacacaac
     4141 aagctatacc atagtcatct ccccagtatg ctctcattaa atcatcattt tcatactgta
     4201 ctgaacttgt atctatagat actttagaac agaaatcttt gaatccttga ggtaatttag
     4261 ttgaccatag aactgttaag tttggttctg gagaaggtcc taatgtatat agagtattta
     4321 acattctaaa tgagttttta gtaactaatg ttctaccatc tattcccata cctcctatac
     4381 actcagttac ccaagttggg tctccagaga ataggttatt gtaatcagga gttcttagga
     4441 acttaaccat tcttaatttc ataacaaaat ggtccatata ctcttgtaat tcttcttctg
     4501 ttacgattcc agcttttaaa tctctttcaa agtatatatc taagaaagta gatgttctac
     4561 ctaaagacat tgcagcacca ttttggtctt taacagcacc taaataacca aagtataacc
     4621 attgtacagc ttcttttgag ttagttgctg gttttgatat atcaaatcca taagattcag
     4681 ccattttttt aagttcattt aaagctgata tttgctcagt tatttcttct cttaatctga
     4741 taacttcctc atccatgcaa gaaacttcta atgatttctt ttgctcattt ttatcttcta
     4801 ttaaagcatc aacaccgtat agagcaactc ttctgtagtc accaattatt ctacctctac
     4861 cataagcatc tggaagacct gttattatac cagattttct agcagctctc atttctggag
     4921 tataaacatc aaaaactcct tggttgtgtg tttttctgta tttagtaaat atatctttta
     4981 tttctgggtc taattcatat ccaaaagctt cacatgaatt ttcaaccatc tttataccac
     5041 catatggcat gacagctctt tttaaagggg catccgtttg taacccaact attgtttcta
     5101 attctttatc taaatatcct ggagcatatg cagctattcc agaaacagtt tttgtatcaa
     5161 catctaaagt accaccattt tctctttctt ttttaaatag gaccattgct tcgtcccata
     5221 attttttagt attttcagtg gcaccagcta agaaagagtc atttccctca tatggagaat
     5281 agtttaattg tataaactct ctaacattta tttctttagt ccatcttcct gttttaaatc
     5341 cttgccatgc attcattaag tatttcctcc ttagatttaa atgataaata atactattaa
     5401 aattaatttt tatatactta atttatttta tatatttttt taaaaatata ttttctaata
     5461 taataatagc atattattcg tatcctgtat acataaaaaa taaaaaattg tcgctttaaa
     5521 gtataaaaca gattatatgt taataatgtg gtgaaattat acccatatat aaataaaata
     5581 aaacaaataa atagctaatt aaggagaaaa tattttttat tttttgttta ggataaataa
     5641 attttattat ggaaaaaaga aaaagcatac atcttcacaa actgaatatt tatttaatag
     5701 ggggaggtga tagattgttt atcacagtgg tattattttt agtaggtttc ctattaatta
     5761 ctaaaggcgc agatatcttt ataaattgta ctgtagagat aggtaaaaaa acgaatatat
     5821 cagaaattat acttggagct actatagtta gttttgcaac aacattacct gagtttacag
     5881 tgtctctact tgcttctatt gatggtcata ctactatgag tttaggaaat gcagttggtt
     5941 ctataatatg taatacaggg ttagcattag ggttggttgt ttttataagt ccatttaatg
     6001 tagataaaaa aatgtttttt tctaagtctt tactattaat agtatccgtt atagttttaa
     6061 ttttattgag tttagatgga gttataacaa gaggtgattc attattactt ataataatat
     6121 taatctttta tatggttaat aattatagaa gtgtcgttgg aaaatctgat actaaaaata
     6181 gaaatattaa aaataacact attaaagaca tatctactaa aaaagggaaa aattatagag
     6241 gtttttccgt attagaaatt gtaaaaatac tattactttt tgctacagga ttgataatga
     6301 tgataatagg ttcacaaatc cttatagaga gtggagtaat aatagctagt tttttaaata
     6361 tacctcaagg tatagtaagt ttaactataa tagcacttgg aacttctctg ccagagatag
     6421 tttcgtcgat tactgctata agaaaaaatc atcatgaaat atcagtagga aatattttgg
     6481 gtgcaaacat attgaatata gtatcagtaa tagctgtatc agcaatacca aataacatac
     6541 caatactatc tcaaaataga caattggata taccattcat gatattatta ttattaatag
     6601 taataatacc aacacttaaa tctaataaac ttagtagaat acaaggtata ttgatgttat
     6661 tcacatattt tctgtacata tcaattttgt atttcatgta tattatttaa ctatactgtt
     6721 taaaatatta attgcagaat atcctaaaaa agtatataat ggataggtta agattaattg
     6781 ataacggaga ggaataatat atgaatataa caaagtttga agatttacca ataagtgagg
     6841 gaataaaaaa agctatagct gaaatggggt ttgaagaacc atctcctata caagcacagt
     6901 ctatacctgc gattttgtca ggtaaagacg ttataggaca agctcaaact ggtacgggaa
     6961 aaacagctgc ttttagtatc cctatactag aaacaataga cccaaataat agaagtttac
     7021 aagctgtagt gctttgtcca acaagagaac tggcaataca agtatcaaca gaaataagaa
     7081 agttagctaa gtattcgcac ggaataaaga cattacctat atatggtggt cagccaatag
     7141 atagacaaat aaaatctcta aagagtggtg tgcaagttgt aataggtaca ccaggacgta
     7201 caatagacca tatcaatcgt aaaacattaa agatggataa tgtaaaaatg attatattag
     7261 atgaagcaga tgaaatgcta gatatgggat ttagagaaga tatagaaatg attttaagta
     7321 agattccaga agaaagacaa acaactttct tttcagctac tatgccaaga ggaattttgg
     7381 aattaactaa gagatatcaa aaagacccag agcatataaa agttgttaga aaagaactta
     7441 cagtttcaaa tacaaagcaa tactatatag aaactaggtc atcaaataaa ttagaagtat
     7501 tatgtagatt agtagatgta tatgacccta aactatctgt tgttttctgt aatactaaga
     7561 gaaaagcaga cgaattggta ggagatttac aagcaagagg atattttgca gatgcattac
     7621 atggtgactt aaaacagact caaagagata tagtaatgga taagtttaga aatggtacaa
     7681 tagatatact tgttgctact gatgttgcag ctagaggtat agatgttgat gatgttgaat
     7741 gtgtattcaa ctatgactta ccacaagatg aagaatatta cgttcataga attggtagaa
     7801 ctggtcgtgc tggtagagaa ggtatgtcat ttacttttgt atttggaaaa gaaatgagaa
     7861 agatgaaaga tatagaaaga tatactaaat ctaaactaat aaagcataat ataccaacaa
     7921 taactgatgt tgaagagaaa aaagtaggta ctttctttgc acaagttaaa caaactatag
     7981 aagaaggtca cttaactaaa caattacaat ggttagaagg tttctgtaat gatgaagatt
     8041 atgcaatggt tgatatagct gctgcacttg taaaactatc tctaggtgaa gaaatgaaag
     8101 aagaaataat agaagaaaaa cctagaagag agcgtggaga tagaaaaggt ggtactggag
     8161 ctaaagatgg tatgattaga ttatttatca atattggtag aaatcaaaga gtacaagcaa
     8221 aagatatagt tggtgccata gctggagaag ttggaatacc aggtaaagta gtaggtacta
     8281 tagatatata tgataagtat acttttgttg aaatacctaa aaaagatgca aaaacagtaa
     8341 ttgaaaagat gaaagatatt aagataaaag gtaataagat taatatagaa aaagcaaata
     8401 agaagaaaaa ataacgtata gtatacaaaa ctataattag aaaatatata aaataatata
     8461 ttggatattt aaaaagcctg atgtgttttc aaaacagata gtagataatc tgtaagagtt
     8521 aacagcataa ggcttttctt gttttatatg atgttataat tttccagatt gttgtgaaaa
     8581 atgtatatta gttccttttt ttcaaatctg atttgaaaaa gagaatatta attatctata
     8641 tagtttagat tataataaaa aatgtaagat aacaaagggg agaaaaagat gtcaatgact
     8701 tatatggacc ctagggtttt tttgatttta gaaatggtgt tagaagaaga cacaaatact
     8761 ctagaacaat tttcaaatgt tttgggtgtt agtactagga ctatcagaaa ctatataaac
     8821 cagattaatc gagaattaaa aggtggtatt gctaaaatag ttaaaaatga aaaaggtaca
     8881 tatagtataa gaattgagga tgaaagtaaa ttaattgaga ttgtaaattt taatagagga
     8941 aagctatcaa attttataaa tttaaattca cctgatgaaa gaataaatta tgttcttgat
     9001 attttaacta tgaccaacaa tccaattacc atagatgatt tggctgaaga gatatgtata
     9061 ggaagaacaa cattaataaa ggatttaaaa aaagcagaca gaattttagc tgaatatgat
     9121 ttagaattaa aaaggaagcc aaatataggt atgattttag ttggtgaaga aatggatata
     9181 agattattaa tccttgatag attgtatgaa aattatattg atgtcttgga aaacgttaat
     9241 cagataaatt tagttaaaga ttatgatatt gaatgtctta gagatgaatt aaaaaagtta
     9301 tttaaaaaag aagaactcta cataacagaa caggtcttga gagatgttga aagatatata
     9361 atcatgtctg tcttaagaaa tctaaatggg tacaaatttg aaaagataga taagagattt
     9421 gaagtgataa gatgttcaga tgaatatact ttaggattaa agctcaaagc tttattggaa
     9481 aagatattta atatagtttt aaatgaaaaa gaaaccatat ttttgacaat gccattaata
     9541 ggtagaaaag ctcctagtac aaaattagca cttagcagta taaagataaa tgatagcgta
     9601 aaggaagttg tagatgaagt aactagtttt ttattagaga cctcagggat tgattttaaa
     9661 gaagataaaa agcttataga aaatttggaa tatcacttgt attttgcact taatagaatg
     9721 agattcaaca taagggtaaa aaatcctctt ttacaagaaa taaaggaaag atatacattt
     9781 ccatatagtg ttgcaaagat agctgcaatg ataattgagg aaaagtttga cttgaaaata
     9841 tgtgaccacg aaataggata tatagcatta cattttggaa gttattttga aaaaaattca
     9901 agaaaagttc taaatgtaaa tagggtagct gttgtttgtg gaacaggtct tgggactgca
     9961 caacttatta gaataaagat aggaaaaata cttggagaaa gtgtagaagt aaatactttt
    10021 tctgatatag aagctaaagc taatttagat ttattaaagt attatgattt agtatttaca
    10081 acagtagatt tcaaaacaga cttagatgtt ccaattttta gagtaaatgc gttatttaat
    10141 gaagaaagta taaagaaaga gatagaaaat gcaatacttt tgaaaaatag tataaatctt
    10201 aagtctataa aaaagattga aaaaaatatc ccttttatag gtaaattaat tgaagaggat
    10261 aagttcttta tattgaataa gagtacgttt atggaaaatt tagaagatat gttagaaaaa
    10321 ttagttcata aaggaattat tgatatagag ttcaaaaaaa aggtattaaa aagagaaaag
    10381 aaatcttcaa cagcattaga taattatata gcattgcctc actcagttaa tactaatggg
    10441 gaaaatcttt atctggcatt tggaatatta gaaaaaccag tgatttggga tacaaaggaa
    10501 attagaataa taatattgat gataattcca gataagaatg tagatagtac agacctgata
    10561 ataaaaagtt atgaagaagt acttgaagta gggagagata aaaagatggt agaagaactt
    10621 gctaaggcaa aatcatttga tgaattttat aaaataatta ccaagaggag gtaataatat
    10681 ggacccagta atttttatta tagcatcact tattacagtg tatttattaa atatttttct
    10741 tggatactta cagcttaaag attttaataa aaattatatt gaactaaaaa gaaaaggaag
    10801 agtggcaatt ggcagaaaaa aaggaagaat ttcatcgggt acaattgtgt tgatacttat
    10861 aaatgatgat ggtgtgattg tcgagactag aaaaatgcaa ggtgttacag tattggcaag
    10921 agtaaagtca tttgaaggtt tggtaggaaa gaacttagag tatatagaaa aatcagattt
    10981 aactgtttac aataaactac ttaaaaaagc aatactagat gcagtcaaac agtacataac
    11041 atttgagaaa aataaatgtg aagatacaaa taatctgagt actgatgaag agtgtaggat
    11101 ggaagtagtt taaaaaaata tatttataag gaggagttaa tatgacgcaa ttttttcaag
    11161 tattagcaag tggtgcagat agttttatga atttatttag ggcaggtggg caacaatttg
    11221 taggttttgt aacagatata gtaccacttt tagtagcatt attagttaca atgaatgcaa
    11281 ttatcaactt tattggtaca gatagagtcg agagacttgc aaaaaaatgt tctgcaaata
    11341 tatttactag atatttgata ttaccagtcc ttggtacatt tgtatttgca aacccaatga
    11401 cactatcatt aggaagattc ttgccagaaa agtttaaacc tagttacttt gcagcagcaa
    11461 gcttttcatg ccatacaatg aatggattat tcccacatat caatccaggt gaactattta
    11521 tatatctagg aattgcaaat ggtataacaa ctttgggatt ctcaacagca gatttagcag
    11581 ttagatattt gttagtgggt atagttgcaa actttattaa aggtgtagtt actgactata
    11641 caacaaaatt tgtagagaaa caacaaggaa tagcattaaa ttcagatata aagattggat
    11701 aattacttta aggtataaat aaatttttca aataaaaaga tagtgtatag aggaggataa
    11761 attatatggc atttaacaaa gttaaaatag taaaaggttc tggaggatgg ggtggaccat
    11821 tgataataga accaacagaa aagaagaata aggtagtata tgtgactggg ggagcaaagc
    11881 cagaaactgc agtaaaaata gctgaactta caggatgtga gttaatagat ggattttcac
    11941 agggtgttaa agatgatgaa atcgcatgtg taataataaa ttgtggtgga acattgagat
    12001 gtggtatata tcctcaaaag aaaataccga ctataaatat aatgaaaaca ggaaaaagtg
    12061 gaccattagc aatgtttata aaagaagata tatatgtttc aggggtaaaa ccaacaaatg
    12121 tagagcagtt ataattgagg tagtaggagg gaagaaatat ggcttatgat actaaaaaga
    12181 agataagtga gcagagtcaa ggaattgttg caaaaatagg tatagcacta ggaaatgtga
    12241 caagtactct ttttcaagct ggtagggata ctatagatac attaatacat actatactgc
    12301 cttttatggc tttcgttgca gtcctaatag gtataataaa tcaatcaggt ataggaaatt
    12361 gggtagccaa tttacttact ccattaatcg gaaatgttgg aggtttagtt gtcttatcaa
    12421 taatatgttc atttccgttg ttgtctccgt ttcttggacc aggagctgtt atagctcaga
    12481 tagtgggagt attggttggt acagaaatag gaaaaggaaa tattccacca agtttagcat
    12541 taccagcatt gtttgcaata aactcacaag cagcttgtga ctttatacca gtaggtcttg
    12601 gtcttgcaga agctgaacct gatacagttc aagtaggagt tccgtcagtt ttatattcta
    12661 gatttttaac aggtgcacca actgttctat tagcatggtt agcaagcttt gggttatata
    12721 aatagaagaa tactttataa ataattagag agaggttcag ttgatatgga attaatatac
    12781 agtactcaaa taaataaaat aggagataat gcaaatgaat ttttacaaca taatatgttt
    12841 gtaactttca aagataatgc tcctcaagag ttagaaaatt actgttatat acattctgaa
    12901 aataatttag taaaagaaat acttacggat gatgtgctat caataaataa tgttgattac
    12961 aaaattactt ctgttggtga gttagtaaac caaaatcttt cagaattagg tcatataaca
    13021 tttaagttta caggtgaaaa agatggagca attggaggaa ccttatatct tgaagaaaaa
    13081 gaaatagcac ctattggcgt aggtactata ctaaaaataa ttagaaaata aaatttaaaa
    13141 cgaatctaat catattataa gtaaattata gataaaagtc aatttaacta atcaagttaa
    13201 cttttaatgt gataaaaaag gggaaatgaa aatgagaaaa gtggctttag tcgttggagg
    13261 aggaagaagt ttaggtgaat atttatctaa acatttagct aaagtaggtt atgatgttgc
    13321 tattgcagat ttaaatgaag acaacgcaaa aaaagtagct gaagaaataa aaactgaatt
    13381 tggttgtaaa tctgtaggat atagttgtaa tgccatagat gaaagacagg ttataagtac
    13441 tgtcaaagct attgaaaatg attttgatag aatagattta ttagtgtaca atgcaggagt
    13501 ggctgtaagt aaaaaaataa ctgattttgg atacaaagat tttaaattta ttgtagacgt
    13561 aaatttaaat gggtactttc tatttgcaag agaagtatct aaagtcatga tagcaaaagg
    13621 tattgagggt agaataatac agataaattc aaaatcaggt agagtgggaa gcaagcataa
    13681 ttcaggatat tcagcaggta aatttgctgg agtaggactt actcaaagtt tagcgctaga
    13741 tttggcagaa cataagataa ctgtaaatgc actgatgctc ggtaatttac ttgattctga
    13801 tatgtttgaa agtttaattc ctcaatatgc agtaaaattg ggaatacctg aatcagaagt
    13861 caagcaagtt tatatagata aagtaccttt aaaaagaggg tgtagattta tagatgttgc
    13921 aaatatgctt acattttatg cttcaaagga agctgaatac tgcactggtc aatctataaa
    13981 tattactggt ggacaagtta tgtaaggttt ttatggagtg tctcaagatg aactctttag
    14041 ttcatgaggc acttttttgt ataaaattaa atatattttc agcatttaaa caatgaaaaa
    14101 gaggtttatc tttattttga gatagcctca tttttgtaat taaaaaacat agtgtttaag
    14161 taaacatata agattgttag ttttttaaaa gagaattttt taataatatt atatttatga
    14221 agtattttta aacttatttt gataaaatat agctatgttt tatatactgt agttttgaac
    14281 atagaaagtt taataaatta tagtatatat gttaattttt aataaggtaa gaaagtagaa
    14341 agaaggatat tttatggata taataaaaaa attaagtcat gggtgtacat tagattgtca
    14401 tgactgttgt aaattcaatg tttatactaa aggaaataat gtagtaaaaa ttgaaggaga
    14461 taaaaatcat ccttatacaa aaggttttat atgcaaaaaa gggatggccc atttagatag
    14521 attaaatcat aaagatagaa taaagactcc tatgcttaaa gttgatggag tatggaaaga
    14581 gatttctttt gataaagcta tagaaataat ggcagaaaag cttacatact ataaagaaaa
    14641 gtatacatca aagtctgtca tgcattatga ccaatatgga agtgggtctg tgctaaaata
    14701 cataggagat atatttttta atttttatgg aggtgttagc agacataaag gtggtccctg
    14761 ttggagtgca gggatgcatg ctcaaaaata tgattttgga gtagctaaga gtcatgctat
    14821 agaagatatg ttaaatagta aaagtatatt tgtgtgggga aaaaatccag catatactac
    14881 aattcatact atgcaaataa ttaaaaaagc taaagaaaaa gggataaaga tagtagtgat
    14941 tgaccccata tatacaaaaa cagctcaaat agcagataag tatgtacaag taaatcctgg
    15001 aacagatgga gctttagcta tagctatggc aaaaattata gtagaagata aattatatga
    15061 tgaagaatat ataaactcgt atgttattgg ttttgaagaa tataaaaaat atttatcttc
    15121 attggaatta agttttttaa ttgatgaatg tggtgttaaa gagaatgata taagagagtt
    15181 agtggattta tatactaaca aatattcaag tataaatgtt ggatatgggc ttcaaaaata
    15241 taaaaatggt ggaaacacaa taagagcaat agatgcttta ggtgctataa ctggtcaaat
    15301 aggatttagt ggtggagggg taaactatgc taataaagtt tatccgagtg ttataaattc
    15361 tgacccttac aatagccaat catatggtga agatagggag ttttatgtaa gtaatatcag
    15421 taaatttata gaagaatctt taaaaaatac atcaaataaa gtaaattatg catcagatga
    15481 acttgatatg acatcaaata aagtaaatta tgtatcagat gaacttgata taacatcaaa
    15541 taaaacagat tatatatcaa atgaattgta taatttatct aataagtcaa tcaaaggtaa
    15601 tattcctata aagatggctg taataactaa aagtaatatg ctgaatcaac tgccagattt
    15661 agtagaattg gagagggtgt tttcaaaaat tgaatttaaa gtatgttttg atatgtttat
    15721 aactgataca gctactttat gtgacatgtt tataccgtgt acaaatacac tagagagtga
    15781 agatataatt tatagctcaa tgaccaatcc atatataacc tataatgaaa gagctgtaaa
    15841 gccagcacat aaattgatgg atgaatatta cttctttatg gagctagcta aaaagatggg
    15901 attaaatgat tatccttttg tagaaaagag aacttattta gaaaaagtga ttgaaccact
    15961 taagcgtttt gacaaaaatc tggatataga aaaacttaaa aacaattact ttactataca
    16021 taaccctgtt gcttgggaag ataagaagtt tgagactcca tctggaaaat acgagcttta
    16081 ttcagaaagt ataaaaaact tgggaataag tccaacacct gtatatataa gcaataaata
    16141 taaagaaata gaagataaaa atatttcttt tagattatta actaatcatc atgcagatac
    16201 tttatttagt cagcatttta tggacaaaaa atctatagct caagcatata taaatcggag
    16261 aatggctaaa aaagtaggta ttgaggacaa agatattgtg atattgaggt caaaaaaagc
    16321 aaaaataaat gtacaaataa atatagatga tggagtaggt aattatatag taaaaatgta
    16381 tgttggttgg tggaagaaac atggaaatcc taatagttta acagacactg gtatatcaga
    16441 ttttgggggt caggtaacat ataatgaaag tatggtagaa ataatacgac aaaactagtt
    16501 aaatttcatt gaaggaataa aaatataatt atagaattga ttaaaagtta ctatttttac
    16561 aaaactattg aaggagggat ttttgatggt aaattattcc ttagaacata agaatctata
    16621 catagaattt atgtgctcag aactagacca ccatgtagcc aatgaaataa gggaagaaat
    16681 agataactta ttaagtgtaa atcaagtaaa aaatgttgta tttaattttg aaaatattaa
    16741 ttttatggat tcttcaggta taggcgtcat cataggtaga tataaaaaga tttctaatga
    16801 agggggacga gtttcagtaa ttaatataag ttcacgagtt aagaagattt ttgatttatc
    16861 tgggttaaat aaaattattg gcatttatga tacgtatgaa gaagctctaa gttctttgta
    16921 gggaggagta tgtgatgaat aatattatgg aagttaaatt ttcggcaata tctgaaaatg
    16981 aaagtttagc aagagttata gtagcatcct ttgcagctaa gttagaccca acagtagatg
    17041 agttagtaga tataaaaact gctgtctctg aggctgttac gaatgctata atacatggat
    17101 atgaagaaga cagttctaag tttgttttct taagatgtga gatagaagga aatactataa
    17161 agattatagt tgaagatgaa gggtatggaa tagaaaatgt ggagaaggca atggaaccac
    17221 tttatacatc aaaaccagaa cttgatagat caggaatggg attcacagta atgaaaagct
    17281 ttatggacga tgtagaggta agttctgtaa aagataatgg gactagaatt gaaatgacta
    17341 aaaaaataaa tgtgcctaaa taaagtccaa aagtgaggtt ttattatgga agtaactgtt
    17401 gccagagaag aaaaaaaacc tcttcttagt catgaagaga ctctagaact tattgaaaaa
    17461 gttcaaaatg gagatgaaga ggcaaaagaa atattaatat caagcaattt aggtctagtt
    17521 aggagcgttg tatctagatt tttaaatata ggatatgata gagaagattt atttcagtta
    17581 ggttctatag gcttaataaa atcaatatat aaatttgacc caaaatttaa tgtaaaattc
    17641 tctacttatg cagtaccaat gattttaggt gaaataaaga gatacttaag agatgatggt
    17701 atgataaaag tatcaaggtc gttaaagcaa atagctataa aggcaaagat ggaaagtgaa
    17761 gctttaacta aaaaattagg tagagagccg agtatagaag aattagctaa agcaatagat
    17821 gtagaaaaag aagatttagt aatggctatg gaagctaatt tcaatgttga gtatttgcaa
    17881 ggagttattc atgaagagga aggttctcca atatgcctta ttgataaaat aagcatgaaa
    17941 ggagaaagtg aagaagaaaa agtagtggat aacatattgt taaaagacat acttggaaga
    18001 ctggataaga gagagcgtca aataatagtt ctcagatact ttgaagacat gactcaaagt
    18061 gaaataggag agatgctcaa tatatcacaa gttcaagtat ctaggataga gaagaaagta
    18121 ttgtctaagt taaaagaata tatatcgtga taatacttat gatatgtaga ataataaaat
    18181 ataataaata tattactaaa ataaaatgta ataacttttt atgttaagtt tttaaattat
    18241 taaaagatat taaaataata aaaagcatta aaaaagtaaa aatataaaaa caaggtgtct
    18301 ttatggaaaa atagattttt tctttattag gcatcttttt tattttttga ccaaacttta
    18361 gatagtcaaa ataaataata ggtttatttt tttaaaatta acaaataata ctttagagag
    18421 gtgtttagta tggataaaaa ttataaaaaa tatgtagacc aaataagccc aaaacctaca
    18481 tatttaaaaa actatacact tgcatttatt gtaggtggaa ttatttgtat gatagggcaa
    18541 gcaataaatg atttgtatat gaaagttgga ggtcttgata aactaggtgc tagttctgca
    18601 acatcaataa cattaatatt tataggggca tttttaactg gattaggagt ttacgaccta
    18661 ataggaaaaa gagctggagc tggttctata attccaataa caggttttgc taactcaata
    18721 gtatctccag caatggagta taaaagagaa ggctatgtat taggtgtagg tgcaaactta
    18781 tttaaaattg caggaccagt tttagtttat gggataggtt cttctatttt atgtggaatt
    18841 atttattata tttttaagat gttttagatg atttttattt aatttaaatt ttattaatta
    18901 tgaagaaggt ataaaatctg aaaatagcta ctaaagtaac taattgaaaa ataattctgc
    18961 agatttaatt aatattttta attaatatta aaaatttgaa tagtaaaatg caaaattaaa
    19021 aaggtgtgaa aatatgaaaa ataaaagaat tggaaaaaga acagtcaagt tagaaaataa
    19081 accaaccata atatcaactg gaactatagt aggtcctaag gaaggtgaag gaccactaaa
    19141 ggactatttt gatatgatta tgactgacga tttatatggt gaaaagactt gggaattagc
    19201 tgaaagtaaa atggtagaga ctgcatctca acaagctatc caaaaggcag gtaaaaaatt
    19261 gtcagatgta aattatatgc taggtggcga tttaataaat caaatagttc cagcatcctt
    19321 tgcagcaaga gaactggcta ttccattttt aggtatatat ggagcttgtt ctacaatggc
    19381 agaaggtctt tgtataggtt ctatgcttat agatggtggt tttgctgatt tagtactgtc
    19441 aggtacatca agtcactatt gtacagcaga aagacaattt agattcccac ttgaacttgg
    19501 aaatcaaaaa ccaatgacag cccagtggac agttacagga gcaggaagtg tattattagc
    19561 tcctaatgga gacggtccaa aagtaaagta tgttactgtt ggtaaagtaa tagatgaggg
    19621 tattgatgat ggtaataata tgggaccagc tatggctcca gcagcaatag atactatcta
    19681 ctcttacttt gaagatacta atgatgaccc aaatagcttt gatataattg ctactggaga
    19741 tttaggtact cttggaaaac agatagcaga agactttcta aaagaaaaag gtgtagatat
    19801 atcaaaagtt tatactgact gtggtataga gatgtttaac cttaaagaac aagatgtcca
    19861 ctgtggtgga agtggatgtg ggtgttcagc tacagtgttt gcaggatata tatatgataa
    19921 gttgagaaaa aaagaattta acaaagtaat gcttgtatca acaggagcac tactttcacc
    19981 gacaagtaca ctacaaaagc agacaatacc atgtgttgca catgcagtag taatagtaaa
    20041 tgagtaggaa gtgatataat atgttaatgg actatgtaag agtatttatt gtaggtggaa
    20101 ttatatgttt aatagcccaa gtaatgatgg attatttcaa aatgcaaact ccatatgtta
    20161 tggtaacgta tgtaacaact ggtgtagttt taacttttct aggactttat gagccattag
    20221 ttaagtttgc agcagcaggt gcaacagttc ctataatagg atttggatat tcacttgcta
    20281 caggagtaat aaaatcaatt caaagtgatg gttttttagg tattttttta ggaggtacaa
    20341 ctgctacagc tggtggaata gcagcagcta tattctttgg atatattatg tcagtagtat
    20401 ttactccaaa agcaaaacca taaatcttta ttaaaagaat aataagtttt tgaaataata
    20461 actttttata aagcaggtgg atatctttta gattccacct gttttttata taaagaagcg
    20521 tttacataat tgaagttgac aattatttac aacatagtgt agtattatat tatcaaaata
    20581 aaatgaagtg aagtagggga taaagatggt aactattaaa gatattgcaa ggaatctagg
    20641 tatcagttat tcaactgttt ctaggtgctt aaacaataat cctaatgtat ctgaaaaaac
    20701 aaaaaagaaa gtggtagaag aggcaaatag actagggttc cattttaatg taaatgcaag
    20761 aaatttagca aaaaaagaaa ctaacaggat aggggtaatc ttttcaaata attttaatca
    20821 tcaagatact agaaagtttt ttagtgatat aatggatagt tctataaatt ctattgagac
    20881 taataaatac gattttataa tacagcctaa taataacatt agtggtgata gtaatgtata
    20941 taaaatggta aatggacaaa tggttgacgg attagtaatt gtgtctcaat caataaaaaa
    21001 agaagagtat gattttttaa aagacaataa ttttccacat gtatttatat attttaaacc
    21061 atcttttata ggagaagtag ataatttctt ttgggacgat aacgtgtatg gaggttatat
    21121 agctaccaag catttaattg accatggtca taaagatata ataacagtaa cttcagatga
    21181 taagagttca aaaatgcatg aagatagaac caagggatat ttgaatgcta tggaagaagc
    21241 aaatttaaag acagaagtca ttaaatctaa aatggatttt gaatctcaag ttgaattttt
    21301 agaaaaatac attgataaaa taaaaaaagc ttcagctata tttgtacaac aagatgtacc
    21361 agcgatttct ataatacaag agttaaaaac tacttatggt ataaatgtac cagaagatat
    21421 ttccataata gggtataata atattgaatt aatatcatat tttaggtcgc atttatcaac
    21481 aatagatgac ccaagagagc aagttataaa aaatggagta gatagtttag taaatataat
    21541 aaataaaaag agtacagaac acattccaag aaaattatat ccaaggttaa taatacgaaa
    21601 tagcgttaaa agaataaagt agtaagcttt taagtatcaa acgtttatta aaaatattat
    21661 agattatgtg aagtttttta acaaataata taaataaaaa ttaaaaggag taggtgtata
    21721 taagtacatt gtactccttt atttattgag atagttttta taatatgaat gaataatttt
    21781 attcaattat ttgaaaatcc gttattttaa caatataaat taataaatta tttgtatttt
    21841 atatcatgaa tctataatat ttttttgatt cataactaaa agtatataaa aatgatgaat
    21901 aaatatatat tatacattat caatgatagg ttatataata aaatcactaa caattatatt
    21961 ataagaaaat tataaaaatt acaaggaggt atagaaatga aagaaaaagc agggattaga
    22021 aatgccataa tagcagcctt tataatcaca atattggcag aattaattgg acctatttca
    22081 tttaaagtta tgggaattaa tgtaacttta cttagtatac tatgggctat attcatagga
    22141 atggctgttt ctcctcattt attagggaga gttataccag ccttaaaaaa gtttataggg
    22201 gataatgaaa taaatgtatc tccatattta ttatctttga cactatatcc attagggata
    22261 atgtttggaa ttaatgcagg gcctaaagtt ggtatattac ttcaagcagg accagcactt
    22321 ttattacaag aatttggtca tatgggtaca atgttgatag cattacctgt tggagtagca
    22381 ttaggtcttg gaagaagtgc attaggtggt actttttcat tatgtcgtga cacagcacta
    22441 ggaattattg gagataagta tggattaaac tcaccagaag gtataggaac actaggaact
    22501 tacataagtg gtagtatatt tggaacatta ttattttcat ttttagcacc agtgggtgta
    22561 cttttaggat ttcatccata tgctttagca atggcatcag gaatgggtag tggttcaatg
    22621 atgggagctg caacagcatc attaatgaat acagttccac aaatgtcaga gcagatttta
    22681 gcatattcag ctactagtgg attgattaca gctgttactg gaatatatat agaattattc
    22741 ttatctttac cagtagccaa ctactattat agcaaagtag ctccagttat tgaaagattt
    22801 agaggaagaa aaacaagaag aacaagtaat aaattgtaaa ggaggatata tatatggaaa
    22861 aaacttttaa gactattatg gagcagataa aaatagtatt gtttatatat attattattt
    22921 gctttggaca aatgatagca cttaagactc aggctcaaga tttgttgatt ggaagtgtat
    22981 ctggattttt gttggtgata attgctatta taataaagaa ttttgttaaa aaacctaatt
    23041 taccaggttt tgcatgggct acattagttg catttgtttt atcgcttcca atatctccag
    23101 tgggggatat catagcaaca aatgtaggga aaatcaattt tatgtctaca gtaacaccat
    23161 tattagcttt tgcaggaatc tctgtaggta atcaattaga tatattaaag actttgagtt
    23221 ggaagttagt agttatatca tttatagtta tgacatctac ttactttggt tctgctttta
    23281 tatctcaaac agttttaaga ttaaatggaa tgctttaagg aggtagtaaa tatgaatgaa
    23341 ttaaaagcaa aaattaaaga ggaaataaag ttattatctg aagagaaaaa gacatcattt
    23401 gaaaaagttt ctgactattt attttcaaat ccagaattag catttgagga gtataagtca
    23461 caaaaagcat tatgtgattt gttagaagaa aatgaattta atgtaactaa aggtgtagga
    23521 ggattagaaa catcttttga agctgtgtat tcaaatggaa ctaatgggaa aacagttgct
    23581 tttttagctg aatatgatgc acttccagga atgggacatg catgtgggca caatatcata
    23641 gggacaagtt ctgttggtgc aggtatcata ttaaaagaaa tcatgaaaaa acataatata
    23701 gaagggactg taaaggtttt tggaacacct gcagaagaaa gagtaggtgg aaaaataact
    23761 atgattaaag aaggtgtatt taataatgta gatgctgcat taattttaca tccaagtgat
    23821 gcttcaatgc ctgatgatat atcatttgct caagttaatt taaaatttga ttttactggt
    23881 aaggcatcac atgctgctgc ttttccttgg gaagggaaaa gtgccttaag tggagtaata
    23941 gcactattta acagtgtaaa tagcatgaga ttacatctta aagattatgc aagagtacat
    24001 ggaattataa ctgatggagg tagcatacat aatataattc ctgaaaaatc tacagctata
    24061 tttaatgtaa gagccttaag tatagaatat ttaaatgaga tttgtgaaat gcttaaaaat
    24121 tgtgctaaag gagctgcaat ttctactgga actaatgtag aaatagttca attagatgaa
    24181 atatacaaag agattaagaa tgattctgaa ttagtgaata tagttagaca aaattttgaa
    24241 gttttgggtg aagactatgt tgaaagagat ttaagtcaag gtataggttc aactgataca
    24301 ggaaatttaa ctcatgagat acctgcaata caagcatata taaaattaaa agaaaatact
    24361 gcaactcata cagatgaatt tgctgttgca gctggtggtg aagaaggcag agtagcactt
    24421 ataaaagcaa ttaaggtgtt agcaatgtgt ggagtagata ttttgtatag taaataatat
    24481 ataattttaa aatatattaa gaaaggaaat cggattagac atgatattaa aacaagtaat
    24541 agaggtttat gacattttag ataaagcaaa tgctaatggg gaagaagtaa aaacttactt
    24601 acaaggttat ggtgaagtag atgtaactgt aaaagaattg tcttcaagta aaggttcaac
    24661 agatttagta aagcttacaa ttcctggaaa aaatggaaaa ttaaaaggtg gagatgctcc
    24721 tactcttggt attttaggta gactaggagg gattggagca agaccagaag ttataggttt
    24781 tgtctcagat ggtgatggag cattggtagc aattgcagtg gctgctaaac ttttggatat
    24841 gcaacgaaaa ggggatatat tagatggtga tgttgtaatt tcaactcata tttgcccaga
    24901 tgctccaact aaagaacact atcctactcc ttttatggat tctccaattg atatgatgac
    24961 tatgaatgaa aatgaagttg atagtagttg tgatgcaata ctttctatag atactactaa
    25021 aggaaataga gtaatcaata ctagaggatt tgcaatatcg ccaactgtta aagaaggcta
    25081 catattaaaa actagtgata accttttaga tattatgcag actgtaacag ggaaatctcc
    25141 atttgtattc cctttgtcta ttcaagatat aacaccatat ggaaataatc tgtatcactt
    25201 aaatagtatt ttacaaccag cagtagctac agatgcacca atagtaggag tagcaattac
    25261 aacagagatg cctgttgctg gatgtgctac aggtgcaact aattttagtg atttagattc
    25321 agctgggaga tttgcaattg aagttgccaa gctatttggt agaaataagt gtgatttcta
    25381 tgataaagaa gagtgggaaa tgcttattaa gagatatggc aaattaaata gatttcaaac
    25441 atttggtata cagtaattag aaaaatatta agtttatata atttgtgata taactattta
    25501 agaatatata aacaattagg aataaaagta agaataaagc acttagttaa aaactttaaa
    25561 aataaaatat ttatttgttt atataaaaag gaggattctg gttattggga ttctcttttt
    25621 tatgaataca aataatatat tgtaattata aaaaaaggag cgtttcaaag tgattttttt
    25681 aatcaccttg agacaactcc ttatattttt atttaaattc tattttttat taagttgctg
    25741 gagttccacc accatcagga ggagtagtag agccaccacc attatttcca ccaccatcag
    25801 gaggagtagt agagccacca ccattgtttc cgccattatc aggaggagta gtagagccac
    25861 caccattatt tccgccatta tcaggaggag tagtagagcc accaccattg tttccgccat
    25921 tatcaggagg tgtagaaccg ccaccattat cacctgtgtt attattgtta ttattatttt
    25981 cttctggttg gttattgtct ggtttttttg tatcttcaga tgatggttga gaacttactt
    26041 tagtaggagc agtaccttca ataaatgctg ctttagagcc agaagattgc tttcctccat
    26101 cctctaaatt aatttttgta aaatatacat ttttaggaac ttcaaattca gtaaccgtta
    26161 aattagcatg tattttttcc ataatttttt cccatagttt tgcagtacta gtacttccat
    26221 gtggtacttc tctacgtttt atagtgttac cagaatcatc ttttctacca gcatcatctc
    26281 caatataagt tgcaccaaca taataaggag tgtaaccgac aaaccaagca tcatatgcac
    26341 tatttgtagt acctgtttta cctgctacag gcattccctt tggaagtgta gcaacaccac
    26401 cagtaccttc agtaattacg ctttctaaca tatctgtaac aacataagct acttcagggt
    26461 ctacaacttt atgttcttca ggagcatttt taactaataa ttgaccatca aaggtagtta
    26521 tagtagtaaa aatagaaggt tctacataaa taccgtgatt tgccaatgta ccataagcag
    26581 cagccatttg aagtggagta ataccattcg ccataccacc tagtgtcaat gatgggaatt
    26641 ttctatcact tgcttcagat gaacctgagt gattattctt taaagttgtt ataccaaagt
    26701 tctttaagta atccatcatt atatctacac attcatcata agagtctcca agcatttcag
    26761 cagttttgac agctatcgtg tttgaagatt tagcaagtgc tttacgtaaa ctcatagaac
    26821 catgaccagc agtagtagtt cttggattcc atttattatt ttcttcaaac ttatatcctc
    26881 ctcgagaatc acttagagca gttgcttgtg ttatttttag agtatcaata gctggcgtat
    26941 atattgctaa aggttttata gaagaacctg gctgatgagg gttagtagca cgatttaaag
    27001 tttttctacc acttatattt cttcctccag ctagtgctct tatttcacca tttttataat
    27061 ctaagattac cattgcagct tgcggttggc taactccatc aggaccgacc atatgtcctg
    27121 ggaaattgct atttctatca aattcttctt ctaaagcatc ttgcatttta gggtctatag
    27181 ttgtgtttac aattagacca ccattgtaga ataagttttg agcttcatca tttgtatgtc
    27241 cttgttccat taaagcattt ataacttcac tttcgataag gtcttctaca gatgaagaaa
    27301 ctttatctga tgattgaggc aattttattt ctattttagc tttgattgct tcatcatatt
    27361 cactttgttt tatatatttc aattctaaca ttttctttaa aacaatttct tgtctttttt
    27421 tagcttcagg attacttaca gcctttctaa caactaatgt acctgctttt aattgtctat
    27481 aagtatcatt agatataagc tcccaagatt ttattttttc aatcatatca aagtccactt
    27541 gagtagggtc atctaaatca tcatcagttg tgttaacaaa aaataataat ttattctcta
    27601 aatcctcctt agtttcattt ccctctaact tagaagtttt ataggctgaa aatcttgatg
    27661 gatttttagt tgaaccagca agaagtgctg actctgctag agtaaggtca gctgcagact
    27721 tatcaaaata accacgtgca ccagcctcag cacctgctag acctctacca acgaagaagt
    27781 tatttaaata agtttctagt attttatctt tacttactgt tttactcatc tcatgtgcat
    27841 agtaaatatc ctttatttta cgaggtatag tttgctgttc agttgttaac agcattttgg
    27901 atacctgcat aggaatagta ctaccacctt gcttagtacc tgtaagggtc tttaatactg
    27961 acctaaataa acctttaata tcgacaccct tatgctcata aaaacgctca tcttctattg
    28021 caattacagc atgttgaaga taaggggaaa tcttatctaa tggaacgggt gtctttttat
    28081 ttacacttgg agctgtagat aatgtttttc cattagcgta tttaatagta gttgtttggt
    28141 tcgtctgttt atctaaaaca gcttctgtaa ctggagttac atctcttagt gacgcaaata
    28201 ctagaccagc agtacctgct gtaccaacaa ctagtaaaac taaaaatact atcccaaata
    28261 ctcttagttt tttaaattta tcgctttttt tagatttttt cttgtttttt gttgaacgag
    28321 tcttgttagc tgaagttcta ttaattggtt tatttgtatt accagatgag ctaacttttt
    28381 ttctcctgat tttatttcca tttttatcat tatcgttatt cataagattt taacctcctt
    28441 acttaatgca atattataac acaaatagga gtagttttgt aattaataga aaaaatgaat
    28501 ttgctataat attctgtaca ttgtatatgt ataaacgtaa tatattaaaa agtctatatt
    28561 tttattttat ttatttttga caaatattat aaaaattatg ccaaagctac atataaataa
    28621 ataggagggg ataattttga atagaatagt agatagaaaa acaaaaaatg aatttagaaa
    28681 aatcatagct atttttttag taattctttt cttgtctgta tttataggca gttttatata
    28741 tatagataaa actttaagac cgacaataac agttttagca gagactaaag ctcttgaact
    28801 agcaaatagg tcgataaata aagctgttgc tgagatggta gaaggaaaaa taaattatga
    28861 agatttaatg gatatacaac ttgataataa tggtaaaata actatgatac aagcaaacac
    28921 tataatgatg aatgaaattg catctgcaat agctttagaa atacaagatg aattaaaaaa
    28981 ggataagaca gcaagttctt acatacctat aggaacagca ttaggaagtc ctatattagc
    29041 taaatacggt cctaaacttg aagtatctat tgaacctata ggaacagtat cagtaaactt
    29101 taaaacggaa tttgagtctt caggtataaa tcaaactaga catagaatat atttagaagc
    29161 tcaaacacaa gttaaagtag taataccact tataacttca acaaaacaaa ttaaagctca
    29221 aatacctatt tgtgaaacta taatagtagg tgatgttcca gaaagttatg taaatattcc
    29281 agaaaaaaat ctaggaaatg ttttacctaa cactggaaag aataccaaca agtaatgtaa
    29341 agttgtatat ttttaaataa attcaaaata atagtttata aataaaattt ttggaaataa
    29401 tattaatata attttaataa aaatttatat tttatactat gtaaaatatc taatatattt
    29461 ggtctgtagg ttaaataaaa gtacctttag accaaatata ttattaataa cttaataaca
    29521 tcttaaaact tatttattta tattatttac aacatccatt taataaatac accataacct
    29581 acagctgggt cgttttcaat tgcatgtgac actgctccga ttattttatt atcttgaact
    29641 attggagtac cactcatacc ttgtacaata ccaccagttt gagctaaaag ctttttatct
    29701 gtaattttaa ttttaaaact tttactttct ggatgttttt ggttttctat atctataatt
    29761 tcaatattat attttttaca cttattaaag ttatcttgta aaattatttg agcttttcct
    29821 aatttaactt catctaaaga tgctacttta tattttttta acttggaaat atcaaagtta
    29881 ttaatttgac ctcttattcc aaaatcagta ttttctgtaa agctaccaat aatattttct
    29941 cgttttgcat ttatacatcc aacactacct ttataagatt tttctatatt aaggtgctta
    30001 gttgtagaaa ttgaacctgt tttaataggt atttttcttg cattaccaac acttattgga
    30061 tgacctacag ctccaaactc tgatgtatct ggattgatat acgttaaagt agcaaatcca
    30121 gaaagtaaat tgttaaaact aattttttct aatatgtgtt tggtagtttt cattgttata
    30181 agttgtccac ctctatttaa taaaatagat acttgttttt cttctggtaa agcatttaag
    30241 gtattggcaa agtcactata tccatcaact tcagcattat ttacctttac tatagcatca
    30301 cccaatctaa atggagatgc ttctccagga tttctaacta tgatattttt taattctgcg
    30361 tcaatttgaa gtacgtttcc aattggtatt aaatattcag gttcattttt ttgtaaattt
    30421 tgtgcataaa ttaaattatt tgagaaaaaa tataataaaa ataaaaatgt taaaacaatt
    30481 gtaaattttg acttagctaa gttggttttt ttacttaaag tattattttt aaaatgaaaa
    30541 tttttaagtt gcataaaaca cctctttctt attaaattat tttaataata gaattgaagt
    30601 tttcttgctg cttctatatt atgttgtgca agaatcatgt tttgatgctt ggaaaactag
    30661 ctcaataaca ccttagtttt cataaaaata aataaaataa atagtgtata tgataaaata
    30721 aatacatatt catataaata aaaataaaca ataactgtct agcataagaa aggagcaaaa
    30781 aatgaaaaaa tatagattgt tagttacttg tataattgcc atgggaatca taattatagg
    30841 aacatcaaat ccagttagca atttttacaa gactacaaat ttgattagtt caggaaatat
    30901 cacaaatgaa aaagcagata aagatgaaaa ttcaaacaaa aataataaag ataaaaatga
    30961 agacaaatct aattctaaaa gtaataaaga taagtcatca gaggacaaat cgtcagataa
    31021 taaaaatgaa attcaaaaaa ataaaaaact tttaatttgt atagacccag ggcatcaagg
    31081 aaaaggagat agcaatttag aaccagtagc tccaggttct tcctctaaaa aagcgagagt
    31141 atcttcagga acagagggta ttgctacaaa aaagccagaa tatgttttaa acttagaagc
    31201 atctcttgtt ttaaagagta tattagaatc taaaggttat aatgtaataa tgactagaga
    31261 gacacatgat gtaaatataa gtaattcaga aagagcaata cttgctaatg acaaaaaagc
    31321 agatatggtt gtaagaatac atgcagatag tttaaataat tcttcaaaaa ctggagcatc
    31381 tatattgatt cctgaaaaag atggaaaata tacagctcct atatatgaag aaagtaataa
    31441 atgtgctgaa tttatcaaac agaatatgga acaatcaggt atacaaatca atggaatcgt
    31501 tcaaagaggt gatttgactg gattcaactg gtcaaaagta ccagctgtat tagtagaaat
    31561 gggatttatg agtaactata atgaagacca aatgatgtca aatccagact accaaagaaa
    31621 aatgatgcag tgtatagctg atggattgga tgcgtatttt aaataagata tgaatagaga
    31681 aaaagttagg ttggtattat ttgcctaatt tttatctcta ttttttattg tacataacac
    31741 aaagaagaag tttattttag gttaaattgt cgtaaatata actaaaaata ttgggaatac
    31801 ttgatttaag tttaaaaaga atatattata gtatagaatg tgtaaaattt ttttgagagg
    31861 tgttgaaatg ctagtagtag aaaatgtgag tcatggattt ggtgcgagaa caatattaga
    31921 aaatgtatcc tttagactta gaaaaggtga acatattgca ctagttggtg ctaatggaga
    31981 aggaaaatcg agttttttaa atataataac aaagaagctt atgccagatg ctggaaatat
    32041 aaaatggtct tcaagagcta cagtaggtta cttagaccaa catacggtat taagcaaggg
    32101 aaaaactata agagaagtgc ttagagaggc ttttaagcat atgtttgact tagagcaaga
    32161 aatgattgct atgtatgaca aaatgggaga agctagtgat gatgaaatga gtaagcttct
    32221 tgaagaaaca gcagagatac aaactatact tgaaaatagt ggtttttata tgatagatgc
    32281 aaagatacaa gaagttgcaa atggtcttgg tcttggagaa attggtcttg ataaagatgt
    32341 aactgactta agtggagggc aaagaacaaa agtacttctt actaaacttc tacttgaaaa
    32401 tccaactatt cttatattgg atgagcctac aaactattta gacgaagagc atataacatg
    32461 gcttactaag taccttcaag agtatgagaa tagttttgtc ttagtttctc atgatattga
    32521 atttataaat aatacatgta atgtaatata tcatatggaa aatggagagt taaatagata
    32581 taaaggaaat tatgatgaat ttgtaagact taatgatata aagaaacgtc aagaagaaca
    32641 agcttatgat aaacaagttg aagaaagaaa aagactagag gattttgtag ctagaaataa
    32701 agctagagta gcaactagag gaatggctaa cagtaggcaa aagcaacttg ataagatgga
    32761 aatattagaa agaccaaaag aaaaaataaa acctactttt gcttttaaag atgctagagc
    32821 agctagtaaa ataatttttg aaacagaaaa tttagtttta gggtatgatg aagcattgac
    32881 aaaaccactt aatttccatt tagaaagagg aaaaaagatt gccttaaaag gaatgaatgg
    32941 tattggaaaa tctaccctat taaaaacttt acttggaata ataaaaccat ttgaaggaaa
    33001 tgttaaatta ggtgactatt tggaagttgg atattttgaa caagagagtt caagagaaaa
    33061 tagtaataca cctatggatg aagtttggag tgaatttcca gggcttacaa actttgaagt
    33121 tagacaggct cttgcaaaat gtggacttac aaatgaacat ataacgagtc aaatgagagt
    33181 attaagtggt ggagaagctg ctaaggttag actttgcaaa gtaatgttaa aaaatataaa
    33241 tttcttagta ttagatgagc ctacaaatca tttagatgtt gaggcaaaag atgaattgaa
    33301 gaaggctatc aaagagttta agggaacagt tcttttagta tgtcatgagc cagaatttta
    33361 ttcagaaatt gttgatgatg tatggaatat agaagatttt acaactaaaa tcgtgtagtg
    33421 atttaactta ttgctggggg gatttcatga aaaagtttct aaatgtactt ttttcaattt
    33481 gtattagtat tgttataata gtaggtgtta ttaattttac tgttggattt aaacaacttt
    33541 attattttga cattgattac ttaaatatat cagagttatc tggtttatct aaagatgata
    33601 taaaattgaa ctacgattat ctaattgatt ataacttaaa taagaatgtg tctgagttca
    33661 aattaccaac attaaaatct tctccacaag ggaagataca ttttgaagaa gtcaggaata
    33721 tatttcaaaa tataaataaa ttagctaaat tattattggt agtttcttta gtaggaatta
    33781 tattgagtgt aaaaaataaa aatataaaaa tcttaaaaac tacatcaata acacttataa
    33841 ttatgccatt attattaaca gttccaattt tattaaattt tgaaaagtca tttattattt
    33901 ttcataaatt attatttaga aatgattatt ggatatttaa tcccgattta gacccagtta
    33961 taaatatatt gccagaggaa tttttttttc actctggaat gatgatttta atattaattt
    34021 tgttagtaag tatagtactg tttgtaatgt ataaattatg taaatcttta tcaataaaaa
    34081 tatttcaatg ttaaatagag ggatattttt atttccaaaa taagataata aaaaaggatt
    34141 agattaaaag ttatacaata aaaatagctg tgcaataata tttagactat gaaagtagtt
    34201 gaaaaatatt tatgcacagc tatttataat agaatttact ttttactagt gattttaact
    34261 aaatcttgaa atttactcat aatgtaattg taattatctt ttttatgagg taatatacaa
    34321 ctactgcaat ctttgatacc tttatctgta tacctaaagt ttccaccaca gttttctcct
    34381 aaagcataca aaggacaata gcaaaataga cagttaaact cttctggttt attagtttta
    34441 tgacaaggga aaaattcgca atctttgtga ttaaaaaact tataattttc gcccatattt
    34501 tcctcctaat taaataaaat ttaaattttt tatactatat aagattttgg tgataatata
    34561 attatactaa ataattttat gaatagtcga taatatagta ttattaatca tagtattaat
    34621 ggtataatta gtcaacagaa aaataatgta aaaataatgt aagtgtattt tgtaattaga
    34681 atatgtttta taacaaaaaa tgaggtgatt aagtgaaaga aattcaagaa aaagcacttc
    34741 ttgtaggtct gaatttgact acaatagtga aaaaaaatga tgatatagac actaatgaat
    34801 ctatggaaga attaaaagaa ctaacaaaag ctgctggggc agaagttgta ggtagcttaa
    34861 ttcaaaataa acactctgta gatgcagctt attatatagg aaaaggtaaa gtagaagaaa
    34921 taagagccta tagtgactct ttagatgcta ctttagtaat ttttaatgat gaattatctg
    34981 gtgctcaaat cagaaatata gagaatgttg ttggaagaaa agtaatagat agaactactt
    35041 taattttaga tatatttgct caaagggcac ttagcaaaga aggtaaatta caagttgaat
    35101 tagcacaatt aaaatataga ttgccacgac tttatggaat gggtggtgag atgagtagaa
    35161 caggtgcagg gattggtact agaggtcctg gagaacaaaa actagaaata gataagagac
    35221 atatacttaa taaagcagca gatataagac gtgaacttaa agaagtaaaa aagaatagag
    35281 agacacagag agttaagcgt ttaaagtcaa atataccgat tgtagcactt gttgggtata
    35341 caaatgcagg aaaatctacc ctgttgaacg aattaataaa gacacacaag gattatgaac
    35401 aagaaaaaga agtttttgta aaagatatgc tttttgcaac tttagatgta actttgagaa
    35461 aggctctttt gccgaataaa aaagaatttt tagtagtaga tactgttgga tttgtaagta
    35521 aacttcccca tgatttagta gaagcgttta aggcaacatt ggaagaagta cagtatgcaa
    35581 atttaatctt acatgtaatt gatgcaacaa atactagtta tgaattgcaa aaaagtacga
    35641 ctgaaggtgt attaaaagaa cttggtgtaa atgataaaaa acatatactt gtatataata
    35701 aagtggacaa gctagaattg gatatatacc ctaaaagtca agaagatatt gtgtatattt
    35761 ctgcaaaaca aggcataaat atggataagt tattaaatat gatagaaatt gctttaatgg
    35821 aaaatactta ttcagtaagt ttgatgttac cttatgagag aggtgatata tttagtagaa
    35881 taaaagataa atataatgtg gagaattttg agtatgggga aagtggtata acgctagatg
    35941 cagatttaga tgaagaagat tttaatatct atagagagta catactagaa aaataggttg
    36001 aatatggata taaactggga aaatatagat aatcttgaag attattttat aacctatctt
    36061 ctttataaag aatctaaaac agtatctcaa attagtaaaa ttagaaatat ttcaagtact
    36121 gaagcaagtg agcaacttat acaagcaaag ttaaaaataa aggaaatgca aaaagatgat
    36181 tttgaggcat ctaaggatat tttggataaa tttctagaac tagataaaat taagagactt
    36241 gattttatgg atagcttaga tgacgaaaaa atggtatact ttaagagaaa ggttttcaaa
    36301 agaatccttg tagaaaaaaa tgctgaagat ttaattgttt taatttgggc gacaggtgag
    36361 ctaaaagatg ataggttttt gaaattgctt catcagctca caaaccacag acactcagat
    36421 attagaagaa taacttattc agcaatcaga aagattgaat caccaagtag tagagaagta
    36481 ctgcaaaaag gtctctacga caaaaatgca cagactaggc agtactgtgc aaaagctctt
    36541 tcaaaattgg gagatgaaaa cagtttaaag attttacagc agttgaaaga caagaataag
    36601 aattttgaaa aagaatatgt gcttagagct tatgacgaag ccattaagtc attggaaaat
    36661 gcaaaaaatt tgaaaaagta attttttatt aaagcaattt gtttacttaa tgatgtattt
    36721 ctaaagttta acaaggtaat aaataaatta atgggagggg tttcaaatga tagtaagacg
    36781 ttgtgcaggt ggagtagtgt tttatgctaa taaagtactt attgtaaaaa atgatagggg
    36841 tgaatggaca cttccaaaag gaaagatact aggaggggga cttccatatg agagtgctgt
    36901 tcaaagagtt aaagtagaaa ctggcataga tgctaaaatg atagatgtgg ctggcgatac
    36961 tatgtatgaa tttttctcaa gaagtagaca acaagaagtt tgtaatgcaa taatgtggta
    37021 tgttatggaa gcttgtaaca ctgattgtgt acttgctcct gaatttcaag aaggtggatt
    37081 ttataaagta aaggatgctt tagaaatgtt atcacatcat aaagagcaag ctttagtaga
    37141 agtatcttat aaaaagttta aggaattaaa gaaattagtt tcagagggcg atgatgttcc
    37201 agcaaattaa ttgtgaattt agaggattct gaggaaggga tagccccttc cttttttaat
    37261 tgaagcagtt ttaagcgtaa attatatagt ctctttaaac tatgatttat caatttagag
    37321 atttagtagt ttatatttaa aatcagtaag atatatttaa aataaaaatt aaaaagtata
    37381 caattttatt atataattgt cttatgatgt tgattaaaga agtattaaaa gtccatttat
    37441 ttttaaatag aatgatttta taaatatata tttgatgtgt atattagaaa atgattaaaa
    37501 taggaggaaa tacaatgagc aattacagga cattacatga atttggaacg gatgaaataa
    37561 cgattgaaaa gtctgttttt attggatatg ctaagcctat aaagagtgaa gaagaagcat
    37621 tagagtttat aaatgaaata aagaaaaagc ataaagatgc aactcataat gtgtgggctt
    37681 atactgtagg taaaaatatg aatatacaaa gatatagtga tgatggagaa ccacaaggaa
    37741 cagctgggat acctacatta gaggttataa aaaaagaaga tttgagagat gtagcggttg
    37801 ttgttactag gtattttgga ggaacaaaat taggtgcagg tggtctagtt agagcttata
    37861 caaaaggtgc taaactggga cttgaagcag gtaagataat ttataaggta atgtatcaag
    37921 aagttaaggt taagatagat tatactcaac ttggaaaagt gcaaaatgag ttaatgaatt
    37981 tggggtattt tataaaagat actgtatatg aggataatgt tgaaatagta gtatattcaa
    38041 gattagaaga tgtagagaaa ttatcagaaa aaatgattga tataacaagt ggaacaggaa
    38101 aaatagtttt aggagaggaa ttttatttgt ctgaacaaaa tggagaaatt ttaatataat
    38161 ctaaaaggtt attagaatag ttaatacctc aaatagccaa ttagtatttt taagtgaaaa
    38221 gccattaaat tgatttaatc taaatcaatt taatggcttt ttatcggatt ttgcacagaa
    38281 tccttttttt acttcaaata aaccgactaa aagtaaaaat atcccaaata ttttttttaa
    38341 tatatctgaa gacagataat tagctaatag tgaaccaaat acagctccta aaaccccaaa
    38401 cacagctata ggtataacca atttaaaaat tacattttta ttttttatat gtatagcaag
    38461 tgctataagt gtcataggga tagatgaaag taaatttacg ctttgtgcta ttttagtgtc
    38521 tatgccagca agtaaaacga gtgcaggtat aaggattgtt cctccaccca ttcccattcc
    38581 tccaataatt cctgcaaaaa atccaattag agcaaataac attaaaacac catccttaat
    38641 gctgcaatta tcataattat tccaaaagaa attctaagaa actttccagt aaccttattt
    38701 agtaatttag ctcctataat accaccaaga atacttccaa ctgcaacttt aattgttaag
    38761 ttaacatcat aagtaccttt agatacatat aaaacagaac ttgctgtcgt taagaatatt
    38821 attatagaaa gagcagttgc atgagattta tgttcttcta ccttaacgat gtcatttaat
    38881 attggaacta aaagagtacc tcctccagaa ccaaaaactc catttataaa tcctgtaaaa
    38941 actccaatta tcgtattttt taaattaaaa tcaaagtatt ttttctttaa atcatcagtt
    39001 tttttcataa aaatcacctt ctgaaatagt tttaccaaaa taggcaaatt atatttatat
    39061 aaaataagat taaatataat ctttcatgtt tgtttaattt tgcataaaaa aaaacatatt
    39121 aaaacaacat attaatatat ggtataatat attaaaacaa agtagcaaat ttgagaggag
    39181 ataacaatgt caaatataaa aatacaaata gacaaaactg tagaatggct tataaataag
    39241 gttaatgagg caaatgcaaa aggattaatt gttggtgtat ctggaggaat tgattcggca
    39301 gtagttgcta atttaattaa aaaggcattt ccagaaaact ctatgggagt tataatgagc
    39361 ataaaaagta atcctcaaga tagagaagat gcacttaagg ttatagaggg atgtgatata
    39421 gaataccttg atttagacct tatagaacca caaagtgcta tattagacat ggtagtagga
    39481 aatttaaaag ataaacattt atatagagaa gaatatttaa agatgacaga tgcaaactta
    39541 agagcaagag taagaatgag tacaatttat acaattgcta acaatctagg atatctggtt
    39601 gttggtacag acaatgctgc agaaatacac acaggatatt ttactaaatt tggtgatggt
    39661 ggagttgata ttttacctat tgcaaattta actaaaggag aggtgtatga atgggcaaaa
    39721 gagcttggtg ttcatgaaga tttaataaac aaagctcctt cagcaggtct ttgggaaggt
    39781 caaacagatg aagatgaaat gggaactact tacaatatga tagatgctgt attagaaggt
    39841 agattggatg aagttcctaa aagagaccaa gagataattg aaagacttca tagattaagt
    39901 gaacacaaga gaaaaacgcc tgcacaacct cctaagttct aatttactat ttataagatt
    39961 tgtgataaaa tttacaagtg atgaaaatta gaataattaa ttgtacgtat taaggagtgg
    40021 aaatatggga cgtataggta atataattaa tagaaaaggt aaacaagatg ctcaaagagc
    40081 aaagatattt actaaacatg ctagagcaat agcagttgca gctaaggaag gtggagcaga
    40141 cccagagtac aatgcagcgt taaaaacagc tatagaaaaa gctaaggcag ataatatgcc
    40201 aaatgataat atagatagag ctatcgctaa aggtgctgga gcaggtgctg gagaagacta
    40261 tgaaactata gtttatgaag gatatggacc tggtggagtt gctgttatag tagaaacttt
    40321 aactgacaac aaaaacagaa ctgctggtaa cgtaagatac tattttgaca aaaacggagg
    40381 aaacttagga actagtggat gtgtgtcttt catgtttgat aaaaaaggac aaatattagt
    40441 tggtttagga gatggagttt cagaagaaga attgatggat gttgcattag aagcaggagc
    40501 tgaagatttc ataacagaag aagatggtta tgaaataata actacaccag aagatttttc
    40561 tagtgttcgt gatgagttaa aagctaaagg atatgagttt atatctgctg atgtgaagat
    40621 gatacctcaa actacaactg tattgactga agaatctcat ttaaaaatga tgaataaatt
    40681 agttgatatg cttgaagaag atgatgatgt tcaagatata tatcataact gggaagtaga
    40741 ataaatagta taagcatatt gaaatttata agtattgaat caattttaac atgtgataaa
    40801 ttttatagaa taagaaacac taaaatagac atacgcacct ctaacctata tttgcataat
    40861 aatatgtaag cataggtaag gggtgttttt atatttatag gttaagaaat ttaaagtaaa
    40921 ttttgagctg gactcgattg tctataaata attgatgggt atataacttg ttgctgaata
    40981 ccatttatac gcccagttac tgtatcaata atcatcctaa gactacgttc tgctgtctct
    41041 tccattttta aatctataac tgtcaaagga ggaatacttc ttgccattag tcgtgaaggt
    41101 ccattacttg ctgcaaatat ttgaatatcc tctccaatta caattcccga ttcatgaaat
    41161 gcattcatca taccaagagc taccacatca tgattacaaa aaattacttt ttttagtgaa
    41221 ttttttgcaa gcattttttg agcaatatca tatccactat ctattttatt agaacaataa
    41281 tatatagaat ctgatagatg tattccatgt tctttacatg tttttaaaaa agatttaccc
    41341 cttaaagtca tacatgtaaa ggaagttggg ttgaatacaa cagcaatatc atttttacca
    41401 ttttgaatag catgtaaagc tgctatacga ccagtttcct cattatcaat agatacactt
    41461 gaaaaaccag gtatttcacg atttacaaca actacaggaa ttttaggttt attttttact
    41521 agatattcta tatcatcagc attgatacct gttaaaacaa ttccatcata ataattattt
    41581 gcaaaaaagt attcatcatc acatagatga ccaactttgt aaggtcgtat gatgatattt
    41641 atgtttaaat gttctaaaga aattatgtgg tttattgctt gaagtatatt ggttgatgcc
    41701 aactcaaatc cctcatcctg ccaataaaaa gctattttaa tattattatg tttaatagga
    41761 gtagagcgtt tatatccaag cttatcagct gaatttaata taagctcttg tgtatgtagc
    41821 ggaatcctgc gttcatttcc tttaccactt aagacgtacg agacagttgc tgaagaaaga
    41881 ccacagtctt ttgcaatatc tttgattgtt gccatgataa aatcctcctt aaatagttgc
    41941 ttaaatttgc ttataccaat aatcttaaca tatattcaac taaagaacaa tattctacaa
    42001 ggtgcatatt ttacaggatt agaataaata aattaaaaaa aacttcttac ttatgttgac
    42061 ataatttagt ttataggatt ataatatgct taaataagct tatgattaac ttgaattaag
    42121 caaagttaag caggaacatg caatgctagc ttgcaatgtg actgcaaagg gggaaaaggt
    42181 atgagtaagg taaatatatt tgaagttggt cctagagatg gatttcaaaa cctgaaagag
    42241 tttttagaaa ctgataaaaa gcttaagatt attgatggtc ttattgcttc tgggattaaa
    42301 caacttgaaa ttagttcatt tgtaagccca aaagcaatac ctcagatgaa agatgcaaaa
    42361 gaagtagcaa cttattgtgt agaaaaatat cctgatgtga aactttatgc attagttcca
    42421 aatttatatg gtgctaaagt tgcatgggag tgtggtataa gagatatatc ctatgttata
    42481 tctttgagtg aaactcataa taaaaaaaat ataaatcgta cccatgaaga gtctattgat
    42541 gagcttaaaa aaataatgaa tacttatcca gacatgaata tatgtattgg aatggctact
    42601 gtatttggat gtccttttga aggtttacca aaaattgaag atgccataag atttgctaaa
    42661 cgcctttggg aaaacggtat cagggagata aatctagcag atacaatagg gattgctgac
    42721 cctaagcaag taagagaaac tattagtgca ttagttgaag ctttaccaga atgcagatgg
    42781 caagtacata ttcatgatac tagaaatatg ggaatggtta atactcttgt ggctattgaa
    42841 tctggaatta ctactgttca gtctacactt ggaggattag gaggatgccc atttgctcct
    42901 ggagcatctg gcaatactgc aactgaagat ttagtatata tgcttgaacg tatggggtat
    42961 gatacaggag ttgattttgt taaacttctt gaattatcaa aatatcagaa gagttttgta
    43021 aatggagtat atagtggtca tcatgtaaat ataaagtctg atagttgtaa ttgttagttc
    43081 tattgattaa tcgattaaaa aaatatgctg attggtaaaa tagatttatt gataaaaaat
    43141 ataaattata aaatacatta tctaataaaa caaataaaaa aattgagggg gattagtatg
    43201 gatattatag ctttactttt atttttagga gttattatta ttgcatttgt acgtaagaat
    43261 aatgcaggta ttttggctct agctattggt gtcatagctg ttagaatttt tggaatggat
    43321 gataaagaac tttatggagc tataagcaac tcaatgttta ctacacttgt tggtataaca
    43381 ctactctttg caatagtgaa ctcaacagga gcattaaagc ttgttgcaga aaaaattgta
    43441 gctgcttctg gtaaacgtgt ttggcttata cctatagcag tttttatagc aggatttgtt
    43501 gttgctggtg ttggacctgg ggcaattcca gcacttgcaa ttatcccagc aatggctgtt
    43561 cctgtagcca taacagttgg ttataatcct gtaatgcttg cacttatagg tgaatgtgga
    43621 ttaatggcag gtcgtatgac tcctattact ccagaaggtc aaattataac aaccgttgca
    43681 gaaggggttg gaattgaaaa tgttatgcct actatcttag cctgtcaaac tctttctaca
    43741 attgtatttt caatagtatt gtttataatt ttcaaaggat ataaacttaa aaaacctata
    43801 aatgttatag atagtaagca aatagaaaaa ttcaatataa agcagataat ttctctaata
    43861 agcatagtag ttatgattgc ttttatcata atttttgata tgaatgttgg gcttgcagct
    43921 tttgcagttt cagctgtact tatttttttc aatattgctg atgaaggaga atgtatcaaa
    43981 tcaattccat ggagcacgat agtaatggtt cttggagtag gtgcaatgat gacaatcgta
    44041 gatgcagcag gaggtattga cttgatgagt aatgcattat catcactgat gaatagtaaa
    44101 acagctactc caattatgag tatttcagca ggacttatgt ctatggttag ttctgcttta
    44161 gcagtagttt atccaactat gatgcctatg tgtgttgaca tagctaaggc agttggagga
    44221 gtagacccac tagcacttat tgctgcagtt ggtgttggag gttctcttgc tggtgtaagc
    44281 ccactttcta ctggtggggc attgatttta gcagctatgg gttcaagtaa gaaagacttt
    44341 aataaggaag aacaaaataa ggtttttgta cagcttttca ttatgagtgc agttggctta
    44401 ttggttattg cagtagtatc aatattatca tttaatgcaa taacacattt aatgaactaa
    44461 ttagaataac tgaaaataaa tcattaaatt taacttttaa tattaatcaa tataatataa
    44521 tttggagggg aagttatgaa aaaaggagca ttaagcaata taaaggtact tgaccttaca
    44581 agagttcttg caggtccata ttgtacaatg atgttggcgg attttggagc tgatgttata
    44641 aaaatagaga tgccaagaaa aggtgatgat acaagaggtt ttggaccttt tgtaaatgga
    44701 gagagtttat actatgcaaa tataaataga aataaaaaag gtatcactct aaaccttaaa
    44761 tcagaagaag gaaaaaatat atttttagaa atggtaaaac atgctgatgt tgtagtagaa
    44821 aattacagac caggtgtaat ggaaaagtta ggtctgggtt atgatgagtt ggctaaagtt
    44881 aacaatcaaa taatttatgg agctgtatca ggatttggat gttatggacc atattcagaa
    44941 cgtccaggtt atgatattat tgcacaggca atgggtggtc ttatgagtat aacagggcaa
    45001 gaaggaggag aaccaacgag agttggtaat gctatgggtg atgtactagg tggaatgaat
    45061 ttaactattg gtatactcac agcactcaac gctagaaaaa taataggaaa aggacaaaga
    45121 gtagatgttt ccctcgttga ttctgttgta tcgtctctcg aaactggtat acagagatac
    45181 tttgattcag gacaacctga acttatgggt aatagatatg cttcagccta tccttatgac
    45241 tcttttaagg caagtgatgg aagttttgta ataggctgtg gtaatgacaa actttttgaa
    45301 aagttatgta aaaaagttct ttttagagaa gaccttttaa tagatgagag atttaaaaca
    45361 aatcttaatc gttgtgaaca ttacaaggct cttaaaccag aaatagaaaa atggtctgtt
    45421 aagcatacaa taaaagaagc agttgactta atatcagagg ctggagttcc tgctgctcct
    45481 atctataatc ttgattgtgt tacaacagat gaacatatag caaaagcaag agaaatgatt
    45541 gtagatatta gtcatcctat tataggaaat atgaaagtca atggaaatcc agttaagttg
    45601 atgacaacaa aagctaaaat tgatatgcca gcaccatctc taggggaaag taacgaggag
    45661 atttataatg gttggcttgg ttttgatagt gataaaataa aagatttaaa agaaaatgga
    45721 gttatttgat taaaaaatag ctaaacacac ttgtgacttt agtcatggga ggttcagtta
    45781 gaataatatc aaaaaatatt aaatcaatac tgtaaataaa atatagaatt gtcagaagca
    45841 tttaagatgg gaaaagctac ttagacattg agtctttgtg gcttttccta ttttcattaa
    45901 gaattttata ttatcagaat agatatgtac taaactaaag tattaacaat ttaaattaat
    45961 agaaaataaa ctacctaatt atgttgaata aagactactt tagtgaaaat aaacttatag
    46021 agatgctatt taaattattt taatggaaat atcaaaaatg agactgcatt ctcaaaaatg
    46081 agactgcgtt ttttaagtat tttctcgaaa atgagacaaa aatattgttt tatgggtttt
    46141 attgaagaaa aattcttctg tgaattacaa tttaatcaat tttaaagttg aaaattatta
    46201 aaaatttagt gaaatttatg tatatttcgt ttattttatt aaaaataaca attttttact
    46261 aaaaataaag aacttcaatg gtgattggca tagtacttgc tattttatat taacaagaaa
    46321 tgtagaaaaa ataacaatgt ataatggggg gaatatgatg gaatctgtaa tggaaaattt
    46381 gaacaatctt aaggtggagg ttaaggacaa agtctgtgtt attactataa atagacctaa
    46441 agctttaaat gctcttaata gtgacactct tagggaacta tcacaagtta ttgatgtagt
    46501 atcagaaaat gaggcaatat taggagttat tattactgga gaaggtaaag tttttgtagc
    46561 cggtgctgat atacgccaga tgcaaaacta taaaagtgag gaaggcagaa aatatgcagg
    46621 ttatgctcag ggaatttttg ataaaattga agctcttgag aaaacagtaa tagcagcagt
    46681 taatggatat gcattaggtg gtggatgtga acttgctatg agttgtgata ttagaattgc
    46741 atcagaaaag gctatatttg gacaacctga agttaattta ggagttattc catgttttgg
    46801 tggaactcaa agattatcaa gacttgttgg aactggaata gctaaagagt taatttttac
    46861 ggggagacaa gtaaatgcag aagaagctaa atctattgga cttattaata aagtggttcc
    46921 aagtgattta cttttagaag agtctatgaa gatgatgaac caaatagttg aaaaagcgcc
    46981 aatagcaata agatatgcaa aagttgttat taacaaaggg atagatatgg atttaaagaa
    47041 tgctcttgaa ctagagaaag atgttgcagg tttaactttt gctacaagag ataagcaaga
    47101 aggaatgaat gcatttatag aaaagagaaa gccagttttt gaaaataaat agctattata
    47161 actaaaattg gaacaatgta gaatatattc aaaatctaaa tttcgtgaaa aaatacatat
    47221 agtttaattt taaaaggagt taatttatga atacgggagt aattataagt ttagtaggga
    47281 ttatcatagc tctatctctt ctagttgtaa tggttatgaa gggaataaat atttttatta
    47341 tagcaattgt atgttcatca ttagttgcta taacaggaag cctaaatgtg tatgatgcac
    47401 ttaaagtgga ttatatgaca gggtttgttg gatttcttca ggcaaatttc tttattttcc
    47461 taacagggac attaatggga aaaataatgg agattactgg tggagcaaaa tctattgcta
    47521 agatgattgt aagatggatt gggaaggata aagcactact ttctattcca atagcttgtg
    47581 gaatattagc ctatggtgga gtaagtgttt tcgttgtaag ttttgcagtg tttccgatag
    47641 ctttagaaat ttttaaagaa gctgatttgc cacgaagatt tataccagca gctttgactt
    47701 ttggatgctc aacttttgct atggttgcac caggggcacc acaaattcag aatattgttc
    47761 cagcatcaac attagggaca gatattatgg ctggagcagt aaatggtttt atatcatgtg
    47821 cagtaatgtt tatagttgga agtacaattt tgtacaaaat ggtttcaaaa gaaaaagcca
    47881 atggtggtca ttttatagca catgaatcag atatatttga tgaagcagaa gcaactaatt
    47941 ctaagagaga aaatggtccc aatggtgtaa ttgccttaat tccattgata gtgtcgattt
    48001 taataattaa tgtaaaagtt aatggaaaag cgatagtacc aattgaggtg ggagtattta
    48061 ttggagcttt attagtatat ttattgttaa ataaatatca agataatact aaaatagttg
    48121 gacatgttgg tgatgcatgt aaaactacag tagtagcaat atgtaatact tgtgctgtag
    48181 ttgcatttgg ttcagtagta aaatcagcag ttggttttga cttcatagtt aatgctatga
    48241 ctaatattcc tggtcctcct attgcagggg ctgcagttgg aactacagtt attgcaggta
    48301 tttgtgggtc agcttcaggt ggactaggaa ttgcagctcc acttcttgga ccagtatttt
    48361 tagccaaggg tgtttccgct gcagcattaa ctaggactat ggcaatttca tcagcagcat
    48421 tagattcact tccacacaat ggatatattg ttactgtaac aaatggtctt tgtaaagaaa
    48481 cacataagga tgcctatatg ccaatattct gggtaactgt tttaacccca tttattggaa
    48541 ccatagtagc agtcctactg tttacaatgt tcccgggatt gccataggag aaaagataaa
    48601 aggtataaat tatattttga tattataaaa tcaattttca aaatatatac aataaatttc
    48661 atgttttaat actgtaaata tgtatttaaa ataacaaatt gaccatataa ggaggaattg
    48721 aaagtgttaa ataaaccatt agagggagtt aaggttattg acctaacgta ttttgtagca
    48781 ggtccaggga cttctaaaat attagctgac tggggtgctg acgttattaa ggtagagcca
    48841 agctttggag acccaggaag aaagacaggg gcaacaatga caatgccaat agatgattat
    48901 aataatcctt tttacagcac atataattca aataaaagag gtttgtctat aaatcttaag
    48961 agtgaaactg gaattgaaat tatggataag cttttaagcg aagcaaacgt atttgtttca
    49021 agttatagaa caggagcatt aaaaagacta ggtcttgatt atgaatcatt aagtaaaaag
    49081 catccacacc ttatctgggg tcagataaat ggttttggcg attttggacc tgctaaggat
    49141 aatgcaggat ttgatacagt tgccttttgg gcaagaagtg gggctatgct tgatatagca
    49201 gaaaaagata caagtccaat aaatccacct atagcctttg gagatgcaac aacttcttgt
    49261 agtttatctg gaggaatatg tgcagctttg taccagcaag ctaagactgg aaaaggacaa
    49321 aaagtaatgg catctttatt tgggcaagca atatggaatg catcatcttt attagcatct
    49381 acacagttta gtgatgagta tccaaaaact agaaaaaatg ctatttcacc agtaataaat
    49441 tcttatcgtt gtaaggatgg aaagtggata ttcttaagta ttttagagca tgaaagatat
    49501 tttgaggcac tttgtagatt atttggaaga gaagacttaa taaaagaaga gaaatttgca
    49561 tcttcagtag aaagtaagaa aaatgctaca gaacttatta atattttaga tggtgaattt
    49621 gcaaagttta ctcaaaatga gatggttgaa aaacttactg ctgctgatat agctcatgaa
    49681 aaaattcaac atgttaatga tgtagtgact gatgaacagg ctattgctaa taactatata
    49741 tatgaacata caagtaaaga tggaaataag acaatgcttg catctactcc agttaaattt
    49801 ggaaatattg aagttaacat gacttgtgat gctccactta taggagaaca ttcagatgag
    49861 atattgagag aacttggata cagtgattct gatatagaga ctctaattga atctggaatt
    49921 gtaacaatga ataaagaagc atgtgaaata tgttaataaa catgtgaagt atgttaataa
    49981 ataggaggga attttatgga ttttagatta acagaagcac aattaatgct tcaaagagta
    50041 gcaaaagaat ttgcagagaa tgaaatagca ccaatagctg ctgaaacaga taaaacaggt
    50101 atttttccaa gggagctttt tagcaaaatg gctaaaatag gatttaatgg aattggaaca
    50161 cctgtagagt atagtggttc tggtggggca gatatagaaa aggtaattgt tgttactgag
    50221 attgccaaaa aatgtgcagc atctgcagca atattatcaa tacacacaat atatgctcaa
    50281 gctattttga aatttggtac tgaggaacaa aagaaaaaat accttccaat gatggctgaa
    50341 ggtgggtgtg taggtgcttt tgccttaacc gaacctaatg ctggttcaga tgctgcgaga
    50401 gctgcaacaa ctgcaattat tgatgaagaa actgatgaat atgttttaaa tggaactaag
    50461 tgttttattt ctggtggagg tcaagcagaa tcattaataa tatttgcatt gacagaccca
    50521 tcaaagggaa taaagggaat gtctgctatc attgtcgaca aaggtactcc aggtttttca
    50581 ataggaaaaa ttgaagaaaa aatgggtatt catggttcag aaactgcaga gttaatattt
    50641 gataactgta gagttccaaa gtctaactta ttaggaaaag aaggtaaagg atttaatata
    50701 gctatgactt gtttagatgg agcaagaatt ggagttggag ctcaagctgt aggaattgct
    50761 gaaggggctt tagaagaaag tatcaaatat tctaaagaaa gagtccagtt tggcaagcca
    50821 atttcagctt tgcaaggtat tcaatggtat atagcagata tggcgacaat ggtggaatca
    50881 gcaaaattat tagtatatta tgctgcagat ttgaaagcta gaggagaaaa acacactaaa
    50941 gaagctgcta tggcaaaata caatgcgtca cgtactgcaa gagaggttac aaatttagcc
    51001 cttcaaatcc atggtggata tggatatatg aaggattatc cattagagag aatgtacaga
    51061 gatgccaaaa taacagaaat ttacgaaggt acttcagaaa tacacaaagt tgttatttca
    51121 agagcagtac taggatagga ggaaaagaat gaatatagtt gtttgcttaa agcaagttcc
    51181 agatactaat gaagttaaaa taaataaaga gacaggtact ctaataagag atggtgtacc
    51241 aagtataatc aatccagatg atagaaatgc tttagaagaa gctctaaaaa tgaaagatga
    51301 actaggagca gtgattaagg ttataagcat gggacctcct caagctaaaa gtgctttaaa
    51361 agaagctttg gcaatgggag ctgatgaagc ttatttaatc tcagatagag cttttggtgg
    51421 ttcagatact tgggctacat ctacaattat tgctgctgct atagagaagg ttggaaagta
    51481 tgatgtaata ttctgcggaa gacaagctat agatggagat acagctcagg ttggaccaga
    51541 ggttgcagaa tttttaggga taccacaagt tacttatgcg aaagaagtaa aggttcaaga
    51601 tgacaaatta ctagtaactc gttatacaga gacaggggat tatttaatag aagcaaagat
    51661 gccagtttta ttaactgcta taaaagagtt aaacaatcca agatatccaa gtgtcaaggg
    51721 aatcttagaa gcttataata atggagatgc aaagattact gtattaacac ttgcagattt
    51781 agatgttgat acaactcaaa ttggattaaa gggttcacct acaaacgttt ataagtcttt
    51841 tgtaccagtt aaagacaagc ataatgaaat aatagaaggt ataaataaaa aagaaaaagc
    51901 tgagaaacta atagaaatac tattcgattt gaaactagta taggagtgtt aagatgatga
    51961 gagcaaaagt taatcaaggt ataaatttaa atgattataa tggtgtttgg gtaataggag
    52021 agcaaaggga aggtaaaatt aatcctgtta cgatagaact tattggtgaa ggaagaaagc
    52081 ttgctgacca attaggaaaa gagcttgcag ttgtgatagc tggatatgaa gtagagaaag
    52141 aagtgaagga attacttcac tatagtgttg ataaagtata ttacatcaat gaccctcttc
    52201 ttaaagattt cactactgat ggatatgcaa tttcaattgc aaatttaatc gaaagaaaaa
    52261 agccagaggt tgtattggtt ggtgctactt ctataggaag agatatagcg cctagaattg
    52321 caggtaaggt tggaacaggt ctaactgctg actgtacaaa acttgaaata gattcaacag
    52381 ataataagtt attacaaaca agaccagcat ttggtggaaa tttaatggcc actattgttt
    52441 gtccaaaaaa tagaccacag atgtcaacag ttcgtccagg agttatggca aaagctgtaa
    52501 gaaacgaatc agagactgga attttagaag ttgttactcc agaacttact gaaaaaatga
    52561 ttagaactag attagtagag atacttccac aagaaaagaa atctgtaaat ctaactgatg
    52621 ctagaataat agtatcaggg ggaagaggat taaaaagagc agaaggattt gagcttataa
    52681 aagaattggc tgataaattg ggggcagaga ttggtgcttc aagagcagca gtagattcag
    52741 ggtggataga acattctcat caagtgggac aaacaggaac tactgttaga ccagaactat
    52801 acattgcatg tggaatatct ggagcaatac aacatttagc aggtatgagt gattctaaat
    52861 atatagttgc tataaataaa gatgcaaaag cccctatttt tagtatatgt gactatggaa
    52921 tagtaggaga tttatatgaa attatacctg aaatgataga atcattaaat aggtaacttt
    52981 tagaaaacat tgaatatgta gaatgataag tcttataata ttgtattgta agacttatta
    53041 tttttgctga aggttatagt ggggagatga aacaatgaaa gagcagtggt ataaggatat
    53101 atttgcaaga gtattatcta tgactgatga tggttttatt gttgtaaata caagtggagt
    53161 aataatagat attaatgata aatattgtga ctttttagga aaagaaagaa aagatataat
    53221 aggacaaaat atacaaagta ttataccaaa tacaaaaatg ctagatgtta tgaaaaataa
    53281 gtattgtgaa gaaggagcta tacatcatta ttcaggtgga aatacaaaag aaaaaagtgt
    53341 aatagtaagt aggtcttatg tggaaaatga caatggagaa gtagttgcag gagtagctca
    53401 agttaaattt agattgcaat catttgatgt agctaaaaag ttaatgtcag aatatatgga
    53461 gctccaatat tataaagagc agtttaagga taactgtggt tttgacaagc tcataggtga
    53521 aaatagagac ttcatagaac ttaagaaaac aggtgtgaaa gcttctaaaa caaactttcc
    53581 agtactttta acgggtgaaa caggcacagg taaagaagtt tttgctagag caattcacaa
    53641 taatagcagt aggtcagata aacctatggt tagtataaat tgcgctgcaa taccagaaga
    53701 attattagag tcagagctat ttggctatga cgaaggagct tttacaggag caaaaaaggg
    53761 tggtaaaaaa ggtaaatttt tagttgcgaa taatggtaca atctttttag acgagatagg
    53821 tgacatgcct ttgaccatgc aagcaaaact tttaagagtt cttcaggaaa gtgagataga
    53881 accagtggga ggtcttaaaa ctataaagat agatgtaaga gtaatctctg ccacaagaaa
    53941 gaatttaagt aaaatggttg aagagggatt atttagagaa gacctatact atagattaaa
    54001 tgtaataaac attcatatga tggaattgaa ggacaggcaa gatgatattt tattgctagc
    54061 aaattatata ttaaacaaat taaatgttga atacaaggaa ttgaaggttt taagtgataa
    54121 ggttaaaaat tgttttatta actatacttg gccgggaaat ataagagaac tacaaaatgt
    54181 aataaaaagt gcctatgctg taagtgatga tatggtcatt atgatgtgtg accttccatc
    54241 taagatggat aatatcagca gagtagctca atgtaatgtg gatagcaatt gttcaattca
    54301 tgaaatggtt gagaattatg aaaagagctt aattattgat gtgttaagga agtataattg
    54361 gaaatgttct aaggcagcag aggttatggg aatacacaag agtcttttat ataagaaaat
    54421 aaaaaagtat gaaattgaat taaataatta agataacttg aattaaggca atgctaaaaa
    54481 agcgccctta ttcaaagcga actgtataaa ctgttttatg cagttaaaac gtgtaaaagt
    54541 agatgtgaag tactaatgtc aatcattagt acttttttat tatatttata attactatct
    54601 atatttcagt atcttttgat atctaagatt attatgttta atttagtata taacaaaacc
    54661 ctcttagtta tggacagttt tttatatttt aactgtctac taagagggga tagtttagtt
    54721 taaatttaga gtaaatttta tctagcattt ataaaaaata ttttgaatag cttttttgtt
    54781 atttagtcat aattttctac ttctttatca agttctttgc cacaagaatc acacttatat
    54841 atagcattgt atccgtaatc atattcatca actattttct tttgtctaaa tacaccacca
    54901 cactcacata ggaaaccaat ttttataagt gtaacgataa attgtgattt tataaatttt
    54961 atatcattgc atttatcgtt agtgtaaaat gtataaatat aagagttatc gcactcatct
    55021 cttaattcaa atctttcaat atatgtgtta ttttttaatt cctcaaattc ttctttagtt
    55081 aaatatgatt tttgttgcaa ttcatgtaaa cgcttaattt ggtccattat ttatatcctc
    55141 ccaataattt tagtatttta agcttagata aggaatctaa gttttattaa atttatccca
    55201 aggaattatt taaatcatat ttagttttat taattacaac atatataaat tacacgaaaa
    55261 taaaactaat tgtaaaaata atatcctgtg aaaacctaaa ctactaaccc cttactaacc
    55321 cgaaaactaa aaaaagaaaa tatatccaaa tataagtgat atataaataa agatgtttca
    55381 tataaattta actttaaata ttctgacaat aatatatata aatatattat agttaaaata
    55441 taccacatat tttgggtatt gtatactgga attagagtaa ttaatttatt ttttaacata
    55501 caaatgattt tatgaaaaaa aacaagactc aaaaattttt atattctttg atagaataaa
    55561 attgagagta aatttattga attttataaa atttataagg ggtgagtcta agatatgcat
    55621 gaagataaaa atgatatatt tgaatcaata gatactgagg attttgataa taaaacagaa
    55681 gaagaatgtt tagagctagt aagaaaaaat ggattgaatt taatatacat aaaaaatcaa
    55741 acagaagaga tatgtctaga ggctgttaga caaaattgta atgcaataaa atgtgttcag
    55801 aatcagacag aaaaaatatg tatagaagca gttaaacaag attggagaat gttagaattt
    55861 gtggaagagc caacagaaga aatttgcatg ttggctatta accaagatgg aacagcatta
    55921 aaatatatag aaaatcagac agaggagtta tgcttaagag ccgttgaaaa aaatggtgca
    55981 gctttggagt atgtaaaaga acaaacagaa gaaatatgta tagaagcagt tagaaacagc
    56041 gaatttggat tggcaagagt gaaaaatcaa acagaaaaaa tatgtatgga agcagttaag
    56101 cattgtagct ataatctaaa atgggtagaa aatcaaacag aagaaatatg tatggaagca
    56161 gtgagacaaa atgggcttga tttgaaattt gtaaaaaatc aaacagaaac aatctgttta
    56221 agagcagtaa gacaaaatgg aatggcatta gaatttgtaa aggaacagac tgttggtata
    56281 tgcttaaagg cagtaagaca atatggaatg gcattaaaat ttgtaaagga acaaacagaa
    56341 gaaatttgta cagaagctat aaaacaagat aaaagagcac ttagttttgt aaaaggagat
    56401 aaggaaaaat ataaggctct atatgataat aatgaaccat ttgcaaagag atatgttaga
    56461 aatgtaatag aaaaagaaaa cagagcattg attaaaaaag gagaagaaaa tgcaaaaatc
    56521 aaaattgcag gaaaacttta tgatagaggc atgtcttttg aagatatatc agatatagtt
    56581 gagattgaaa taagcaagtt aaaagtgagt ttaggtgttt tttaaagtaa taaatgtagg
    56641 tgttttttat gggaaatagt taataaaaaa ataatcgact agctctttgt aggacagcaa
    56701 aattagtgat ataatttgat gtataataaa ttatttttat tagataaggg ggaattaaag
    56761 ttgaagatta cagtattata ccaaacaaga agtggaaaca cagaaagggt cgctaagctg
    56821 atagaagagg gcgctaaaaa ggtggatgga gtagatgtaa agcttatgag acttgataat
    56881 attgatttag attatttaaa tgaaagtaaa gcagtaatat ttggaacacc tacttattta
    56941 gcaaatacaa cttgggaagt aaaaaaatgg tttgatgaag attcaaaaaa agttaattta
    57001 gctggaaaat taggagctgt ttttgctaca tgtgattata tatgtggagg tccagatgtt
    57061 gcgatactta ctatagtagg acatttgatg gttaaaggga tgcttgtgta ttctggaggt
    57121 ggttctttag gaaagccatt tatacattta ggacatgtac attcaattga aggtccagag
    57181 ttacaagatg agaaggctat aatatttggt gaaagaattg ctactaaggc aaaagaacta
    57241 tttgcttaat ttctatatgc atagtaatga ttagagtaaa tttagggttt taatggagat
    57301 ttgaagtaaa agttataaaa taaaaaattt tccataaaat tactcaagat gaattataat
    57361 ataattataa ataaattata ttattaaaat atttaaaatc aaacgtcaat agcgagggaa
    57421 gtttatggta tggcatatag aatatgagat tttttctgca attatagtta tttttttaat
    57481 ggtatacttt tttagaagta aatttatacc tactttacaa aacaaaatat attgtgcact
    57541 tttaatattc tcatttttat ttataatttc aaatatttta ggttcatttt gtctaaataa
    57601 tatagacaaa attccaattt ttattacttt tttattgaat cagatatact tattgttatt
    57661 gccaatacca gcagcacttg tatcatttta tgttatggct attatttatc aagatataag
    57721 gtatatgaaa aaaagattat tatttttatc tataccactt ataatttgta taatcttatc
    57781 tattacaaat ccttttacgc atattctatt tggattgtca aaagaaacag gttatatacg
    57841 aggttgtgga tatgttgcaa cttttgcatc ttttttcttt tatgcaatat attcagcatt
    57901 tttatctttt aaatatagaa aagcaatgca tgaatcaaaa atatgggcta ttagaggttt
    57961 tcttatagtt tcaattgtgg caattatctt acaggcaatt tttttacagt atcttcttac
    58021 aggaactgca tgtgcatgta gtttactttt gacatatctt tctatgcaga atcgaggtct
    58081 tattattgat gaccttactg gtgtactcaa tagacaatct tttattcaag agctagattt
    58141 gaatatcaat actgaacaat caggatttat tattacaatt gcgcttgatg attttaagtt
    58201 tatgaatgaa acttttggaa caaaaaatgg agatattgca ctaaaagaag ttggaaaata
    58261 tttgattcag atacatgatg taaaccatgt atatagaata gggggagata tattttctat
    58321 tgttgtcaat agtcaattag gtatagaacc agatgatatt atcagaaaga tagaagaaag
    58381 atttaaaaag ccttggctag tagaagagat aagttttaat ttagcaacta gtattgctgt
    58441 tgtttattac ccagaaaatg cagaaacgac agaagatgta attgttgcta tagatttctc
    58501 tatacatgaa gcaaaacgct ctgagtcaag gcgagttgtt tatgcagatg cgtctataag
    58561 tgaaaagata aagaagaaac atgttattaa aaattgttta aaagaagcat taaaaaatga
    58621 tgggtttgaa gtgtactacc aacctatatt ttctaatagc aggggcaggt ttacttcagc
    58681 agaggcatta cttaggctag aacacaaaga gttaggtttt atacctcctg atgaatttat
    58741 tccaattgca gaacaaacag gattgattaa ctcaattgga ttagtagtct ttgagaaggt
    58801 atgtagattt atagctagtg atgagtttga agatttaaaa ttggataata tagctgtgaa
    58861 tctttctgta gtacaatgta tgcaaaaaaa cttagctgat gatttacttt atcttatgaa
    58921 taaatataat gtatcaccaa ctaaatttaa acttgaaatt actgagactg tggctatggg
    58981 ctcttttaat ataattaaag aaacaatgga aagattaatt gatttaggtg ttaagtttgc
    59041 acttgatgat tttggaattg cttattctgg agttactaat atgctttctt taccattttc
    59101 agtaattaag ttagataaga gtttgatttg gtctatgaat gaagatagta ggcataaact
    59161 tacagttgag acgattatag cacttataaa taaattgaat atgaaggctg tagcagaagg
    59221 tgttgaaacc attaagtgtg ctgaagattt aatagctatg gagtgtgaat atttgcaagg
    59281 gtattatttt tctaaaccag ttccagaaga tgtttttaaa aatttgttga aagaaaatac
    59341 ttttacaagt taacaccctt tattttttta attacaactt tgttcattga cactgccagc
    59401 gatatattat aaaattaaca caataataaa tattaaattt attatacata ttattaatat
    59461 taattaatgg agtaaagatt tattatatat tttatttaat tatcctaaag tgagaaagga
    59521 agatgtgaca tgaataaaaa gaaaatatta gtgccaattg atgggacaga aagaagtatg
    59581 cattctttgg aatttataaa aggaatattt aaaaaagatg aagttgaagt agaaataatg
    59641 aatgtaaaag aactagtatt tattgatggc atatccctgg ctgaagagat aaaaaattct
    59701 gaaaatttag gaagaagaat cttggataaa gcagcagaga taatgggaga gtatgatgtt
    59761 aaagtacatt ttacttttgg atatccagga gatgagataa ttagaaaagc aaaagaagat
    59821 aatgtagatt ttatagttat gacaaaatct actaaaaaag gtcttacaag aatgataggt
    59881 tcagtaacag caagtgtagt taaacaagca aaatgtatag tgatgattgt accggagtag
    59941 aattagaaag gtatttgaaa tatgaataaa aagatagtag cagtttgtga aagtgaaaga
    60001 agtttaaatt ctcttaagac agctgcaaat gatttaggat ttgatttagt ttatgaaatt
    60061 caagaaaatg ataatataaa aaatgaactt tctatttatg atatagaaga tgcatccata
    60121 gtgttatttg ttacaagtga ttctatagaa agcatagaga agattgatag atttatagat
    60181 agagaatttt atgaagttga tccaaagtat ataatagagg atgcaaaatc tatagtaagt
    60241 gaaattttaa tagacttaaa ttaatcgtgg gtgtcgcact aagaatagag cgacgccttt
    60301 ttatatattt tacacaagaa ataaagaggt tgtatcaaaa tatagataag agtctttttc
    60361 attgttgaaa tgatgaaaat atatttgatt tcatacaaaa aagagtacct cataactaaa
    60421 aagttcactt tgagacactc catttttata tgttagttgc atttaaggta aaatagaagt
    60481 ttaatcatgt tgaaataact gaattacatc ttctaaatga ttgtacattg atgtataacc
    60541 taagtaagag tctttactat caaatgcaat cattatcttg ttatggtggc taatcatatc
    60601 cttgagagaa tttctatatt taaaaccaaa gtattggtta gaagaaactg ttttaggtat
    60661 taactcataa tattttataa aaattggatt atgagaagct aaaattatct ctttgtgaaa
    60721 ttgcaagtca gcatcataac attcttctat caaaccatga gaaaccttat ccaattcctc
    60781 tattgacttt aggtaagtat attttatttt ttgaagttct ttagatgtag catttaaaat
    60841 tgctagttta gtagcttcgc tttcgataag ttgtcttgct cttaaagatt ctacataaaa
    60901 ttcttgtatg ttatgatttt tatagatttc accatcatca aataggtcaa cttttttaaa
    60961 tccttcaact ataggacttg aataaggcac agctctaagt attccttcct tacagagtat
    61021 atttatggca tttcttacag gtattctact tatgttaaat aggtcagcaa tctttctctc
    61081 acttggtaat ttactattaa ttttaaaagt tccatttaga atgtttaatt taatataatc
    61141 aataattttt tcagtggcat ttaagctttt cataaaaact cctaaacata taattttttt
    61201 atgattgtat tatatcatag ttaagagtta aatctacttt tttataatat gtataagaca
    61261 ggatagaggc caaaatagct ataatagcca agataaagta tccatattgt attgaagtat
    61321 attccgatat tttaccaact atcattggaa atacagacat tcctatagca taaattgctt
    61381 gaaaaaaacc cattgcagta gatttctgat gttttggtac atttttcata gactcgctag
    61441 taaggtaaga aaggagtata cctgtagata tacctggtag tacttgtagt acaaatatta
    61501 tattaatatt ttttattgtt ggaactaaaa agcaataggc tgaaactaaa ataaaaacta
    61561 aaggaatcca aaattttggt ccatacttag tacaaaattt agtagaagca aagccagaag
    61621 aagcaacagc acacaccatg taaaatatag aagatagacc tatgagggta gaactagaac
    61681 ctaagttttt aagaatttga gtagtaaatg acattgttgt agacatttga ataccctgtt
    61741 gaattaatgc cataaaggaa aaaaatacaa gtcttttatc cttgcagata gataaatatt
    61801 ttttaattga tattttttca ggtatttttt tagaattatg attttttata tttaaggcta
    61861 gaatcgttcc aataactgaa gacaatacac tcatgataca taaggctgtc attcctaatt
    61921 tttcataaaa taaagtactc ataacaaatc caatcaacat tcctagattg tttaccaata
    61981 ttatcgtact tgtagctttt tgttgatgtt ctgtagaaaa aaagttggta tagtgaacca
    62041 tgtaagaaat ccaagttgat gatgatattc cagataaaat gttagctata agaaaaccat
    62101 tgcctccagg agaaaagact cttataagag atgctaaacc agcaaagaaa attccagaca
    62161 gtataaatat tttatgttta tttatggaat cagcaaatac tccaacagga agccttaata
    62221 aacattgtga tattccatat gcacctatta ttataccaat catatttgta gatacattac
    62281 atgcacttaa atatggattt tggaaaggta tatatacata ttgtgaaaac cagaaaaatg
    62341 taacaataga aagtaaaagt aatttttgat tagatatttt tttcatatta tcctccatgt
    62401 ggtattttta taatgcaaat aatataccat ttagattttt taatcaagta ctttctctat
    62461 taaaaaaaat ttaaatatat aattattatt tacaaaaaaa ttatacttta tagttgaatt
    62521 aagaaaacgc ttatgatact ataaagttaa caaatttgaa tatataacag tagacgtgtt
    62581 actggtaatg caggcaagat cgaatcaatt tttatagatt atctatagag tactatgggt
    62641 ataatctatt tatttggttc gatttttttg tttaattggc cataaaacaa aaagcctata
    62701 gttgaaaatg gaggattttt tatggattat aaaaatatag ctcaagaaat tctactaaat
    62761 gtaggaggaa aagagaatgt aaatgaagtg actcattgta tgacaagact tagatttaaa
    62821 gtcaaaagcg cttctaaagt gaataaggat aaattatcta aaactgaagg agtaataact
    62881 gttgttgaga gtatgggtca aatacaagtt gtaattggaa ataaagtaaa aaaagtatat
    62941 gatgaggtca taaaaattgt acctcaatca aataacatag gtaaaaagaa tgaaagtcaa
    63001 gaaaagcaag gtataattaa ttctatatta tcagcagtag ctggtatatt tacacctaca
    63061 atacctgcta tagcaggggt tggtatgatt aaaggtattt tatcagttct tgctatgtat
    63121 tatatgaata aaaatggagt agatataaaa gaaacgcaaa gctatattat cttaaatgct
    63181 atggctgatt ctatattcta ttttatgcct attatactag gatatactgc ggctaaagta
    63241 tttaatgcaa ataaaataat atctatggta ttaggagcta cactttgtta tccaactttt
    63301 actgctttga tggcaggtga agaatctgtt agatttttag gattggcagt aacaaaagct
    63361 acgtatacat catctgttat tccaataatt attgctatat gggctctttc atacgttgaa
    63421 aaagtattag aaaagtatat acctgaggta attaaaataa taatggttcc aactttatca
    63481 ttggtagtaa tgttacctgc aacattattt ttatttggac caatcggaat ttatatagga
    63541 aatgtcataa acttttctta taagtatatt tatgaattaa gcccagcatt gtgtggagca
    63601 tttgtaggtg ggttatggtg tgtgttagtt atatttggtg ctcatagagc attattacca
    63661 ataggtataa gtgatgttgc tcaaacagga agacaaaatt tattggcgtt tgcaggagct
    63721 gcaaactttt cacaagcagg ggctgctcta ggagtattct ttaaaactaa aaatcaagga
    63781 ctaaaaacaa tttctatgtc tgcaactata acagctttat ttggtataac tgaacctgca
    63841 atatacggtg ccaatcttag attaaaaaaa cctatggtat gtgccgtaat atgtggtgca
    63901 tttggaggtg cgataatggg aatgggtgga gcttatggta atgcatttgc aaaccaaggt
    63961 gttttaacta tacctgtata tgctgaagca ggtgcattag gtttcttaag ttatctaggt
    64021 ggttgtgcta tagcattttt tggttcagct atttcaactt atctagttgg atttgaagat
    64081 ttggaagagt cttctaataa ggaaaattca tctataaaag tagaaacgaa ggatggtgtt
    64141 attgatataa cttcacctgt agagggcgaa tgtatagaat tgtcagaagt aaaggatgat
    64201 gtatttgctt caaaagctat gggagaaggt atagctgtgt tacctacaaa aggagtaata
    64261 acagccccta ctgattgtga agtagcttct ttatttccaa cattacatgc aataggatta
    64321 aaattagata atggagcaga aatgttaata catgttggaa tcaatacagt agagttaaat
    64381 ggtaaatact ttacaaaaca tgttaatcaa ggagatttag tgaaaaaagg tgataaactt
    64441 atatcgtttg atatagataa aataaaaaag gctggttatg atgtaactac gccagttata
    64501 gtaaacaata catttgattt tgggcaagta gtttcttgta aatctagtta tgtttcaacc
    64561 aatgataata taatttcatt agtattagct ggtaattaag ttaatttgac tagagataag
    64621 taaattgatt taaaaggaaa taagtaaatc aacaattaaa tacatctaaa agtaagttta
    64681 ttgcaatgaa ttgttaaaga aaataattaa tatggagtaa atctattgca atgaagtaac
    64741 aaagaaaata attaatatag agtaagttta ttgtaatgaa ttgttaaaga aaagagttaa
    64801 tatagagtaa gtttattgta atgaattgtt aaagaaaata attaatatag ggtaaatcta
    64861 tctcaatgaa ataacaaaga aaagagttaa tatagagtga acttattgca atgaatcaac
    64921 aaagaaaata atcaatataa aaaggagaaa tatttatgaa tacaggattt ccaaaagact
    64981 ttttatgggg agcatcatct tctgcatttc aagtggaagg agcttgggat aaagacaata
    65041 aaggaaaaac cgtagccgac tataattctt ttaaaaagtc tcatttacag gcagatacta
    65101 aagtcgcatc agacttttac cataattatg aagaagatat tgaattaatg aaagaattag
    65161 ggatgaaaac atatcgtttt tcaatttcat gggcaagaat aataccagat ggtgaaggag
    65221 agataaacca gaaaggttta gaattttata ataagataat agacaaactg atagagtgtg
    65281 atattgagcc attcgtaact ttataccatt ttgaccttcc atttaaatta gtagagaaat
    65341 ataatggttg ggaaagtaga gaaactgtct atgcttttga aagatttgct aaaatatgct
    65401 ttaagcattt tggagatagg gtaaagtatt ggcaacctca taatgaacag aatttaattg
    65461 ttagagtgga ggagagaatt aatatatatg atgaaacaga ttcatggaag atagataaaa
    65521 tgcgtgctca gatggattat aatctttgct tagcacatgc attagcagtc aatgcatgtc
    65581 atgagatgat aaaagaaagt aaaattggag cagcagtatc atcatctgta acatatcctc
    65641 ttacttctaa gccagaagat gtatatgcag ctagaatgaa tgataatttt aaagtgtact
    65701 atatgcttga tatgcatcat tatggagaat atccagggta ttatatgaag tatcttgaaa
    65761 aaagaaatat agttcctcac atggaagatg gggataaaga gatacttaaa aaagctaaaa
    65821 tggattttat agctgtaaat tattatagga caaattgtgc agaagcttta cctgaagatt
    65881 cacaacatcc atttggatta agagaaggaa ctgttgattt tagtatgtat ggactattta
    65941 aaatgtcaat gaatcctaac ttagaggctt ctgagtatgg agcagcaata gacccatcag
    66001 gtcttagagt tgccttaaat gaatattggc aaagatatca cttacctgtt ataataacag
    66061 aaaatggtct aggagctaaa gatatattag aagatggaaa aattcatgat gactatcgta
    66121 tagactattt aagaagtcat ataaatgcat gtaaactagc tattgaagat ggtgtagaga
    66181 tgattggata ttgtccatgg tcatttacag accttttaag ttcttctcaa ggttttaata
    66241 agcgttatgg acttgtttat ataaatagaa ctgaccatga agttttagat ttaaaaagaa
    66301 tcaagaaaga tagtttttac tggtataaag aagttataga gaacaatgga atagtaaaat
    66361 aaacataaat atatattgag ggttttagta tgtacattac aaaggtatta aataattcgt
    66421 tgctacttgc aaaggatgat aatgatgaag aaataatatt gatggggaaa ggcattggcc
    66481 ataattataa ggccgggtct gagttaaata aaaaagatat agaaaagatt tttgttcttc
    66541 atgatgaaaa tataaaaaag agtattatac aattggcaac agaaatagat gcagaatatt
    66601 ttggtatagc tcaaatgata attgcatatg gaatagaaaa atataactta aaacttatga
    66661 accatatata tttggcctta actgaccaca ttgcctttgc agtgagacgt tttaaagaag
    66721 gtataatgat tgaaaatcac tatttgttcg aaatcaagga atttaatcca aaagagtatg
    66781 atataggaaa atatgctatt actgttttta aggaggttct tggtttagac ctaccagaag
    66841 aagagattgg taatatagca ggccatttta taaatgcaca acaagataat ccttatagtg
    66901 atagaaataa gagaagtgct aaaattgtaa atgctatttt gcaaatagtt cattatcact
    66961 tttctattgt atataataaa gagtcatttt attataggag atttgtaatg catctaaagg
    67021 ccttttcaca aagatttctg gctaatgaac catcaagaga aaaaatagat tttatatatg
    67081 agcaagttca aaaaaattgt aaggaagagt atgaatgtgt gaaaaaggta ggagcttata
    67141 tgtataagga atactccaga gaattaccaa gacaagagga gttatatttg atgattcata
    67201 ttcataagat tttaggagaa ttatgcgaaa atagttagaa tatcttaata tgctagtaat
    67261 attataaaaa attaaaaatt aactgcactt taaatatgaa taattgcatt acttaagggg
    67321 gttgtcttaa aattgatttt tttaattaaa tttgaagctc aactcctttt ttaaaccttt
    67381 atatcattac aactttaatg tttatacgac tgtactttag atgtatatct actttttaca
    67441 tttctcaaca tgcaaaccta ccattttttg cagtatgtta attgaaataa accattgagt
    67501 taaccctaaa tttattctgg acttatagga atagttccaa agatacttta aaatattttc
    67561 tggaataatt gcttatttca catatgtttt attgtgatgt tttgatttaa taaattcttc
    67621 aactctgtat atagtaaatg tattatcatg tttgttttat tcaagcacac ttataatacg
    67681 cttgattttt tcacaatgat gaaatatact aatgggtgtt ataggtataa gaatcgcatt
    67741 acacttgaag aagtaagtga taaatgaggt ataaatcctc atatgataaa ctactatttc
    67801 attgaggaac atattctaag tgatgtcaag atactacaat atgactaaat tcctagtgat
    67861 aaaaaagtct acgaatgagt gtagaaaggg gaactaagat gaataaagtt ttaattatag
    67921 atgatgataa agatctttgt attttgttaa aaaagagtat ttcaattgaa cagattgaag
    67981 caaactattg ccattctggg agagatggac tggttgaact ttcaaaacaa gattatcagt
    68041 tagtagttct agatgtgatg atgccaggta tggatggttt tgaaactatg gaacaaatac
    68101 gaaaatatag cagtattccc atcttaatgc tgacatcaaa aagcgataat tacagcaaag
    68161 tgcatggatt gcgagctggt gcagatgact atctaaccaa accatttgaa attacagaat
    68221 ttactgctcg tgtactgtct ttaatccgac gttacacccg ttttaatcca aaaaatgagg
    68281 agccacagca actttctttc aaaggtttgt tgattgacct tgaccagcat acagttacta
    68341 ccaatggcga acctatgttg cttccaccca aggaatttgg tgtacttctt tactgtgcaa
    68401 ggcatcaggg taagattttg acaaaacagc agatttatga agccgtgtgg ggtgagccat
    68461 atgtatatga tgacagcaat atcatggcta ttatcagtcg cctaagaaaa aaaattgaac
    68521 tagacccatc atctcccatc tatttgcaaa caataaaagg aattgggtat caattcaaca
    68581 cggaggtatg aaaatggatg aacaaacgat aattcttttc ttactcttgc tgtcgattgg
    68641 tctacttttt ctttccatat ttgctttttc caagcttggg catatttaca agcgcctaaa
    68701 agatatagag gagatactgg ctgatgtaca aattggagac gaaaatcgta aaatactaat
    68761 taagccatgt gatgttatgg ctccattggt ttatcagctt aatgagattg tctacgatta
    68821 tgaaaataag ttactttctc tgaaaaagtc ggataaagct agcaaacaac ttatgacaag
    68881 tttatctcat gatgttcgta caccattaac aactctgatt ggttatctgg atgctgtaca
    68941 cagtggtata gttatcgaac aagagcggga ggaatacctt gaaatcgcta ggcgtagagc
    69001 ctacgacctc aaggattaca ttgatgttct ttttgactgg tttcggttga actctgatga
    69061 atttacgctg tcaatagaat ctgtggaaat tgcagagttg tcacgcaata ttttgaaaga
    69121 ctggattcct atattccatg aaaagaaact gaattttgaa attgatattc cagaaaatcg
    69181 actaatggta aacctcgacc cagatggata ttcccgtgtg gtcaataatc tggttcaaaa
    69241 tgttcttgct cacagtaagg ctcggcaaat caagattacc atgagtgagg attccagaat
    69301 ggtattactc cgtgttgagg atgatggtgt tgggattgcc agagaaaatt taccacatat
    69361 ttttgagcga ctgtataagt gtgataaagg acgttcagaa aaaggaagtg gtcttggtct
    69421 atctattgtc agtcaaatgg tggagcgaat gggtggtcag gtttccgtag aaagtgagat
    69481 tggaaagtat accgtattta cagtgagctt accattaata taaaattgtt tttcccccat
    69541 gtgacatgta tacacatggg gattttttgt aagttataaa gttgcaaggt taatacaagg
    69601 ttgttgcaag gttaatgtaa gattgaggtg gtatgataac tttaataaac aaaggaggct
    69661 tttattattt atgaataatt taattattga aacaaaaaat ctcactaagc aatatggtgc
    69721 tcaaaagagc gtttctaatt tgaatattca cgttcagaaa ggtcgcattt acggattgct
    69781 aggaagaaac ggtgcgggta agacgacaac tatgaaaatg ttattgggtc taacaaaacc
    69841 aactactgga gaaattaaaa tatttggtca ggacattcac aataacgaga agaagcttct
    69901 tcctcgaatt ggatgtttga ttgaatcacc agggttttat cctaatctga caggaacaga
    69961 aaatctcaaa atctttgcaa ggcttagagg aataccaaaa aaaaatgcag tagaatcagc
    70021 actggatgta gtcggtttgc caaacaatga caaaaagtta ttttctcaat actctcttgg
    70081 tatgaaacag aggttggcga ttgctcttgc cattatgcat gacccacaac tgttgatttt
    70141 ggacgagcct atcaatggac ttgatcctat tggtattgca gaagtaagaa cgtttattcg
    70201 tgatctctgc acagaacgag gtaaaactat tttgatttcc agtcacattc tttctgaaat
    70261 tgccttgttg gcagatgaca ttggcattat tgaccatggt attttgttgg aggaagaaag
    70321 tcttgcccaa ttagaagaaa aaaacagtaa atacatacat tttgctgtat ctgatgcagc
    70381 acaggcagca aggcttctgg aaacccaact taacctgaaa aatttcaaag tagcagataa
    70441 ttacaatatt atgctatatg atacagatgt ttctgttgca gaaataaatc gtgctttcat
    70501 tctaaacaac attgaggtat cagaatctca tttatgcgaa gatactcttg aagattactt
    70561 caagaaagta acagggggtg aaggaattgc ttgatataat ttcatgtgaa ttttcaaaac
    70621 tcaagcggtt aaaatttata ctgatttcta ttttaggtgc ttgcttattt ccaattcccg
    70681 caacaatttt gattgcaaag gacaacttgc cctttgagca attgttcaaa ttagttgtca
    70741 attttggata ttttttgcta ttaccaattg tattaagtat tgttgctagc caactatttt
    70801 ttatagaaag agataatgat gtattaaaaa atcttgcaac agtgccagtg caaaaaggaa
    70861 aactggctct ggcaaaattg gctgtgttgc tgtttatatc attgttctac tctgttgcag
    70921 ggttaggagc tactatcatt ggaggtttca ttgttggaat agtagagggg gttgctgtaa
    70981 aattaggaat gagcattgct tttggaatta tgttttttgt tactgtactt cctgttgtgg
    71041 tactcattgt atatttcaat cgcagctata ttttttctat tatactttct tttgtatatg
    71101 ctattttcaa ttttagtata tccttaaata ttatcaattt tgaaccaaat aacccaatat
    71161 taagtgtatt acctgctcct gttataatgc gttggtggat ggcattttgg ggagatccca
    71221 ctggcgaata cacggcactt agacagccat atttgctctc aactcctgct tgtgtaggta
    71281 ttttatgttt gataaccatt atagcagtcc tgctgatttg tatgatatac aaaaagcagg
    71341 agaattagga ggtatctatg cttgatataa ttactacaga atttcaaaaa ataaaaagat
    71401 ataatattct atggattggt gttgttgctg ttctgttttc agcactattg gcagtttttc
    71461 aggttgtaag ttcacacggc agtgaccctc taacgtatga gagctttgca aacggagtta
    71521 tctggaataa tttcagtctt agttttccat ttgggattac acttattgga ggatatctta
    71581 ttaaccgtga atatacagac caaaccttaa aaaacatcct aactgttcct atttcattac
    71641 gcaaattgct agtgggaaaa ttaattgcgg ttggaggaat tactgtattg ttaagtcttt
    71701 tcagcttctt atgcacattt attttggggt tgttgttttg caatatcaat atatctgtta
    71761 cactcgttgt aaaatcctta gttcagattt tgtctgttaa tctgtattgt tatgttgctg
    71821 ttttgccgat tattgcttat tttggtcgta aacaaaatgc atttctgacg ggtgtaggga
    71881 ttgcatttgt atacggtttt tgtggtgtgt ttgttgctgg aagaaatctg acagactttt
    71941 atccaatcac agcaggtctt ggtctagttg gatacaacaa tggtgctggt actgtttatc
    72001 agccacttat cggtgctatg actttgattg taattctaat cttgacaact attctacttg
    72061 tatttacacc taattatgat aaagttatga ccatatctaa gaaaaaaggg ataaagcata
    72121 aaaagtattc tcataaataa cataaatatt gtttctatta tttaagttgc tagacagtga
    72181 aaagaaaaaa tctgtcgtac agtgtctata tgctcatgta ttcaagaagc tacagttttg
    72241 atttttcata actgtagctt ctttttgtat ttattaaatc acgactatca taatacttgc
    72301 aataggtata gcgacaagag agagtactgt catatgtgtt ttatatatta cattaagtat
    72361 attctaaaat atatgtttta aataatatat ttgaaaatag gaatatttaa ataaaaaaaa
    72421 taatattata tatagttgac aaaaattggc aaatgagata atatataaat atagaaatag
    72481 taatcattac tattattaaa aagggaggaa ttaattatga acttaaaagg aactaaaaca
    72541 gaaaagaatt taatggcagg atttgcagga gagtcagaag caagaaataa atatacatac
    72601 tacgcttcaa aagcaagaaa agaaggttat aatcaaatag ctgctatatt tgaagaaact
    72661 gctaacaatg aaaaggaaca tgctaaatta tggtttaaac ttttacatga tggtatgcct
    72721 tcaacagagg aaaatttaaa ggatgcagca gcaggtgaaa actatgaatg gactgatatg
    72781 tatgcaaaat ttgctaaaga agctagagaa gaaggatttg acaagatagc ttatttattt
    72841 gaagctgttg gaaaaataga gaaagagcat gaagaaagat acttaaagct tttagaaaac
    72901 ttaaatgaag gaaaaatatt taaaagagat gaagaagttg tttggcaatg tcaaaactgt
    72961 ggtcatgtgt atgtaggtac tgaagcacca gaaaaatgcc cagtatgtga ccatccaaaa
    73021 gcgtatttca atataaaagc tgaaaattat taaaaattat cattattaaa aaggaatgtt
    73081 aactatgaaa ttttctaaac aacgagaact gattttaaat gaaatattaa ataatccggt
    73141 tcatcctact gcggattacc tatatgaaaa cttaaaaaaa gataatccaa atttaagctt
    73201 aggaactgtg tatagaaatt tagctcagct aacggaacat ggctttataa gaaaggttag
    73261 tattccaggg tatccagata gatttgatgg tcgaatagat aatcactatc atatcatatg
    73321 tgaagtatgt ggagaggtat acgatttaga atccgaagtt cttaataatt tacaagaatt
    73381 aatatctgag gagacagaca taaaaataac atcttataac ataagtttta aagggatttg
    73441 taataattgt aaaaggtgta gccaagtagg ttagttttca aattctaaaa ataattaatg
    73501 aggtgagttt atgtgtagtg aacaaaaatt ttttatatgt gagacttgtg gaaaccttgt
    73561 aggaatgata caaagtggtg gtgtacctat tttctgttgt ggaaaaccta tgaaggaact
    73621 tgttcctaat acaacagatg cagcagttga aaaacatgta cctgtaattg aagtggatgg
    73681 aaataatgtt actgttaaag taagtagcac aactcatcca atgactaaag aacatcatat
    73741 agcatgggtg tatcttatga ctgaacaagg tggtcaacgc aaatgtctag cagtagatgg
    73801 agaacctgta gttaaatttg ctttgaatga tgatgataaa gtgatttctg cctatgctta
    73861 ctgtaattta catggattat ggaaggctga actgtaatat ttaaataaat tgagtcaaaa
    73921 aggaggctat aaatgtattt tcatacaaat agcctcctat aaatttatat aaattcaagt
    73981 tttaattttg tttaatgtca atataatata aggagaaaat aatatgtcaa tttataaatg
    74041 tagtgtttgt ggatatattt atgatgaatc taagaatgat aaaacatggg atgaattaag
    74101 tgaagattgg gaatgccctg tatgtacaaa aggtcgtagt tattttggaa agataagtac
    74161 tgtttactat gaagaagatg aaaagatagc agaagacata gttgaagatg aatctaaatt
    74221 aaatactgaa aaagagggag atttaaatta cttaagtaca tatttaagaa gagatgatga
    74281 agttgagaaa catatggata taattcacga aatggctgtt acaggaaaat ctataataga
    74341 acctatgaga actaaactac cagtaatttc ttgggatgat attttaatta tgggtgctca
    74401 attaaatcca ttacctttaa atgagcatga tgaagtaaat acaacaacaa taataggaaa
    74461 aaaagcaaag aaacctatga ttatagaaaa tccagtttat atttcccaca tgtcatttgg
    74521 agctttgtct aaagaactaa aaatagcttt agcaaagggt gcagcccaaa ataagacagc
    74581 tatgtgtagt ggtgaaggag gtatattacc agaagagaag gaagcttcat acaagtatat
    74641 ttttgagtat gtaccaaata aatatagtgt aactgaagaa aatcttaaaa attctgatgc
    74701 tatagagata aaaattggtc aaggaacaaa acctggtatg ggaggtcatc ttcctggcga
    74761 aaaagtaact gaagaaatag caaaagtaag aaataagcct gtaggtcaag atgtaataag
    74821 tccatcttgt tttgaggaaa tacaatccaa agaagattta aagaaacttg tagatgaact
    74881 tagagaagtt tcagaagggc gtccaatagg tgttaaaatt tcagcaggtc atattgaaaa
    74941 agatatggaa tttatagctt atgctaaacc tgattttgta actattgatg gtcgtggtgg
    75001 agctactgga gcaagtccaa agttgcttaa agatgcaact tcaattccaa caatatttgc
    75061 tctttatcgt gctagaaaat acatagatac acatggatta gatatagatt tggttataac
    75121 aggtgggctt cgtatatcta ctgattttgc taaggcaatt gctatgggtg ctgatgcagt
    75181 tgctattgca agttctgctc ttatggcagc ggcgtgtcaa caatatcgta tatgtggttc
    75241 tggtaagtgt cctgtaggag tagctactca ggatgaggaa ttgagaaaaa gattacatat
    75301 agaaaacagt gctaatagag tggcaaactt tttaaatgta agtttagaag aacttaagac
    75361 ttttgctaga atttctggtc ataaagatat acatgattta agtgttgatg atttatatac
    75421 tgttaactct gaaatatcaa attatacaaa catacagcat gtatagattg aagtttgaaa
    75481 ctattagatt ttagatagct ataaaagtaa atgataaata tattttataa aagagagtgt
    75541 cttaaaatga actttttagt tcataagtca ctcttttttt tatgaagcca aatatattta
    75601 tcattttagc aatgaaaaag aatcttatct ctttattttg agatagactc cttctattta
    75661 tgaaaattaa agatattaaa ttgtaaaata ttctgtgatg tcgtactatt aaactaaaga
    75721 ttctgtactt taaagtaaat aaaaatttaa ggagtgatta ttatggaaag attgaagata
    75781 caagttttag ttgacaataa tacttatatt gatagatact ttgttggaga accagcagta
    75841 agctattata ttgagattga tggaaatagg attttgtttg actcagggta ttcagatgta
    75901 ttcatatcaa acgctgaaaa attaaatata gatttaggaa atttaactca tgttgttttt
    75961 tctcatgggc ataatgacca tacaagaggt atccagtttc tagaaaatag gtatgattta
    76021 tctacagttg aacttatttc acatcctaac tgttttatac ctagaaaaca tggagagaaa
    76081 agcataggag ctccattttc tgctgaggaa attaaaaata tttttatgta taatcctaag
    76141 gataagccat ttaatctaag taagaattgt gtgtttttag gtgaaatacc ttctataaat
    76201 gattttgaaa aaagagctaa aattggtaaa tgtaaaatag gagatttgtg ggaagatgat
    76261 tatgttttag atgattctgc tatagtttgt aaaactgata aaggtatttt tattgttaca
    76321 ggatgttctc atagtggaat ttgtaatata gtagagtatg ctaaaaaggt atgtggagat
    76381 gatagagtta ttggtatact aggtggtttt catctttttg aattgaataa taggttagat
    76441 agtacaatac aatatttgga taaagaagaa atgagaatgt tgtacccttg tcactgtgtt
    76501 tcttttaagg taaaagcgaa gatgaatgaa atattgaata taaatgaagt tggagtaggg
    76561 ctgaccataa gtatatagta tttgaaagta tataagattt aagttgaagg ttaaaaagat
    76621 attttctata gaaaatatct tttttgttac gtttatttta agagaaatca atatactttt
    76681 atatgaaata ttgtaaaaaa atttattttt aatgagaata tattttcatt aataaacaat
    76741 tttattatgt attaataatg ttagaataaa tataaataaa tcaaagttac ttacattaca
    76801 gtatattttt tcacaaaata tattgattta ttcttttaaa gtttgataat tccaatgaat
    76861 gtaataaaag aaggaatttt atactatacg attattatta tataataata aagaaaaaat
    76921 tatataataa taaagaaaaa atgtataata tttaacatta aaaaagatat ttcataaaat
    76981 taaaaaacaa agtgaatttg aatactattt aaaaaataaa ataaatatat aaaaaatatt
    77041 taatataaag gtggaaataa gttgaaaatg taaagtcatt ggaaaaatat agttgaattt
    77101 aatgagcaaa aatgttattg ttttatcaat aaagtgttaa aataaaaact ttcaatatca
    77161 ttttagggag gatgatttca tgcaaaaaag tgtaaagaaa gcaaaagtaa cgggctctat
    77221 gttagctatt tttggtgttg caagcgttct ttttagttca catgcaggag gaggatttgc
    77281 tacagggaat caagaaactc agtactatgt gcagtatgga tggacagcac cacttatggc
    77341 aattttagca atgattatac ttactgctac catgagagaa gttatcataa tgtataataa
    77401 taacaattgt aggaattata aggatttatt ttgtgagctt tggagaccat atccaaaact
    77461 tgaaataata tgggagatat attactatct aatggtttta atagctgtaa gtgctgttat
    77521 agcaggtgca gcagcagtat ttcaaagtat aggagtaaat tattttgtag ctgtatttat
    77581 tattggagtt gtacttcttg tctttactat atttggtgct atgcttgtat ctaaagcagc
    77641 tacagcaatg acaatagcta ttctagtatg tactcttact atttttattg ttggtataaa
    77701 agctaaagta ccagaaataa ctgaaatatt atcaaataga acgagtttca cacctggcta
    77761 tatcaagcca atacttaata cttttattta tgcaggtttt caatcggttg ttatacctac
    77821 acttgcagga tgttcaagac cacttcttaa gaactcaaaa gaagctacta aggcaatgat
    77881 aatttcattt gttatgaatg caattgcatt aggacttgct gtaactatgc taatgggatg
    77941 gtatagagaa attattgctg ctgggcaaac aacactccct actctttatg ttgcaggtca
    78001 atctggaaat catactatat acataattta taatgttgca ttattccttt gtttaatgtc
    78061 tacaggagta actactatat ttggtcttgt aaatagattt gaagaccata aagcactttc
    78121 tttcctttct tcaagaatga aaagaagggt atttacagct tgtgcaataa tggtagtgtc
    78181 aatgcttata tcacttacag gattaagtaa tattgttaaa tatggatatg gatattgtgg
    78241 ttatcttggt ctattcacta tagtaattcc atttcttaca ctaggacatt ataagaataa
    78301 gaagtttgca aaggaaaatc cagaagctaa atggccagcg gaattaaatg aaaatgtaaa
    78361 ttagatgtag tagcaaaaaa tattgctaaa gagaatacta taaataagaa tactatagat
    78421 aatatatctg catgtttatt aagattattt gcaaaatcta atattaaaca actataaaca
    78481 agcaatataa aactaagaat aaaagataaa aagagggtat ctcaaaatgg acttttagtt
    78541 tataaggcac tcttttttat atgaagtcaa atatattttc attattttga caataaaaga
    78601 gactaatcct actttggata gcctcttttt tctttaatat aaaatagtat aacagcaaag
    78661 tatagattga tacatgtttt ctgtagcttt ctatatatta cagtgtttgt gtggcattgg
    78721 tattttaagc aatctataaa ttataattct ataattcttc tactaatttt agattctata
    78781 gccgtctcta tttcacttaa cattcgttca tttttagggt caataaaagc acatgtatag
    78841 ccttcttcac cagctctacc agttctacca atacggtgga tgtagtcttc tggtgtttct
    78901 ggtaaatcgt aattatatat atgacttact ccagatatat caagaccacg agaagctaca
    78961 tctgtagcta ttaagtattg tatatctaaa tttctaaatg atttcattat tctttctcgt
    79021 tttgattgag caatatcact atgaagtttt tgacaattat atcctcttat agcaagagct
    79081 tcttcaagat tgtcaaccct tctcttagtt ctacaaaata ttattgccat aaaaggatta
    79141 tcttcatcta gtaccttaca taaggcatct aatttttttc tatctgtagt ttctactact
    79201 tcttgtttta tattattaag agtgatttct tctttttgaa tagaaactac aacaggattt
    79261 tttgtgtatc tataagctaa tttttttact tgagaattta tagttgcaga aaagcatagt
    79321 gtttgctttt tgtttgaagt ctcttttaaa atagcttcca cttcattttt aaatcccata
    79381 agcaacattt ggtctgcttc atctaaaaca aaagtcttta acttactaag gtctattgtt
    79441 tttctattta gatggtctaa aagcctacct ggtgtagcta taatcatatg aatatttcct
    79501 tttagtttct ttatttgaga accaatatct tttcctccat atgctgcaag aatacttaca
    79561 tctttagatt ctttaagttt catagcttct tctgttattt gaatagctag ttctcttgta
    79621 ggagaaagta taagtacttg tatatcattt atatctaatg atatattttc aaatatcgga
    79681 agtaaaaaag ctagtgtttt tcctgttcca gtttgagctt ctgctattac atcttttcct
    79741 tcttttatta gtttaatact ttctttttgt ataggtgtag gtgttgttat tcctgatttt
    79801 tttagaatat ttattgtatt ttcactaatc cctaagcttt tgaaatccat tgttatctta
    79861 cctttcatga aaaattttct tttttattaa ccaattaata atatcatatt tgtaagtatt
    79921 tttagtaaat tttttaatta ttatttatat agcttaaaaa tatattaaga tactttaaaa
    79981 tggaatgtaa cttaaattaa attttagtag gaattttata ggtttatttt taaaggtttt
    80041 ttgaaaataa atctatttaa aaattaaatt aaaatgcaag aaaaacataa taactttcat
    80101 ttttaagaag ttttcacaaa aaagaaaaaa tatagtgcaa taaatgatac aaagtaatat
    80161 aatagattac aagatatgaa aagctaaaaa aataaattgc aaatgaaatt aaaatgaata
    80221 aaaaataaaa aaataatcat aagttagaag tatcaatgaa aaataagact taatgttttt
    80281 aaaattaaaa gtatactaag gggggcatta atatgtgcgt tatatcaaaa gatagagcaa
    80341 aggaaataaa aatagtagat actactttaa gagatggaga gcaaacagct ggggttgtat
    80401 ttgcaaatag agaaaaaata atgattgctg aaatgttaag tgacctaggt gttgaccaaa
    80461 ttgaagttgg tatacctact atgggtggag atgaaaaaaa tgtaataaag cacatatgta
    80521 gtagaaattt aaaatcagat ataatggctt ggaatagagc agtaataaaa gatgttgaag
    80581 aatctatttc ttgtggtgtt gatgcagtag ctatatcaat atcagtatct gacattcata
    80641 tagaaaataa attgagaact tctagaggct gggttttaga aaatatggct aaaacagttg
    80701 aatttgcaaa gaaaaatgga ttatatgttt cagtaaatgg agaagatgct tcaagagcag
    80761 atatagactt cttaactgaa tttataaatg ttggaaaaca agcaggggca gatagattta
    80821 gatactgtga tacagtagga gttatgaatc ctttttctat aaagaatgca atagaaactc
    80881 tttatgaaag aactaatttt gatatagaaa tgcatacaca taatgacttt gggatggcaa
    80941 ctgcaaatgc acttgcagga atagcagcag gagcaaatta tgttggtgtt acagtaaatg
    81001 gattaggtga aagagcagga aatgcagcat tagaagaagt tttaatggca cttaagtgtg
    81061 tttataaatg tgatttaaat aatatagata ctagaaaatt tagaggaata tgtgagtatg
    81121 tagcacaggc atcaggaaga atacttccta catggaaacc agtagttggg gataatatgt
    81181 ttatacatga atctggtata catgcagatg gagctttaaa agacccacat aactatgaac
    81241 catttgaccc aagtgaagta aatcttgaaa gaaaaatagt aataggtaaa cattcaggaa
    81301 gagctgcagt tgtaaataag ttgagtgaat atgaaatgta tatttctcca gaaaacgcta
    81361 ccaagctatt aaatgctata agagctacat ctataagatt aaaaagaagt ttaatggata
    81421 aagaaattct tcaattatat tgtgatatac tagcacatga gaaaggcaca acagaagaag
    81481 aagcagttag aggttcatat atttaagata taattgttta ggaggaaaat atgggagata
    81541 atatagttta taaaataatt aaaaaacata tagtagatgg agaagctgtt gctggaagtt
    81601 caattggtat aaaaatagac caaactttaa cacaagattc tactggaaca atgacatatc
    81661 ttcaactaga agctatggga atagataaag taaagactaa aagaagtgtg gcatttgtag
    81721 accataatat gttacaacaa ggatttgaaa atgcagacga ccataagtat atacaaacag
    81781 tggcagataa atatggagtt tatttctcta agccaggaaa tggtatttgt catcaagtat
    81841 ttttagaaag attttcaaca ccaggagata cacttttagg ttctgatagc cacacaccta
    81901 ctgctggagg tgtgggcatg atggctattg gagctggtgg attagatgtt gctttagcca
    81961 tggcaggagg agcatactat ataaaagcac caaaagtctg taaggtgaat ctagttggaa
    82021 aattaaataa tatggtatca tcaaaagata taatattaga agtgttaaga aaacaaactg
    82081 taaaaggtgg agtaggtaaa gtttatgaat atggtggaga aggtgtcaaa agcctatctg
    82141 ttccacaaag agctacaata acaaatatgg gggctgaact tggagcaact acttcaatct
    82201 tcccaagtga tgaaaaaaca ctagaatttt ttaagagtca aggaagagaa gacgcatggg
    82261 tagagctaaa accagatgca gatgcagttt atgatgaaga gattactata aacttggatg
    82321 aattaaaacc attagctgca aaacctcata gcccagacaa tgtagatgaa gttgaaaata
    82381 taggcaagat taaaatagac caagtggcaa taggaagttg tacaaattct tcttatgaag
    82441 acttaatgaa agtagcacaa atcctgaaag gaaataaagt acataaggat gtgagtttgg
    82501 taatagcacc aggttcaaga caagttatgg agatgattgc tagaaatggg gctttggcag
    82561 atataataag tgctggagct agaatactag aaaattcttg tggtccatgt attggtatgg
    82621 gtcaatctcc aggtactgac tctgtgtctt taagaacttt caatagaaat ttctatggta
    82681 gaagtgggac tttgtcagca caagtatatt tagtaagtcc agaagtggca gcagtaagtg
    82741 caatcaaggg agtgcttaca gacccaagag aatttgatat taaatttaca aatttagatg
    82801 taaatgagtt tttgatagat gatagcatga taattaaacc tgctgatgta ggaagtgatg
    82861 tagaagtagt tagaggacct aatataaaac ctttccctct taatacagag ctaagtcagt
    82921 ctataggtgg aaaagttata ttaaagacag aagataatat aactactgac catataatgc
    82981 catcaaatgc taagttactt ccttttagaa gtaatatacc gtatcttgca aactattgtt
    83041 tcaatactgt agatacagaa tttcctcaga gagcaaaaga caataatggt ggatttatag
    83101 ttggtggaga taattatggt caaggttcaa gtagagaaca tgcagcttta gcaccattat
    83161 atctaggtgt taaaggggta atagttaaga gctttgcaag aatccacaag gctaacttga
    83221 taaatagtgg tataattcca atggagtttt gtgatgagaa agattatgaa aatatatctc
    83281 ttttagataa tctggagata ccaaatattt tagacaatct aggtagtgga attttagaag
    83341 ttaagaatac aactaaagga acttctttta aggtcaaagt agaattgtca gcaaaagaag
    83401 ttgatgtatt aaaagctggt ggaaaattaa actacactaa aaatcaagct aattaatatg
    83461 aaaagaggga atattgaatg tataaagtga cacttatacc aggagatgga ataggaccag
    83521 aagttgcgaa agctatgaaa aaggtagtag aagctactgg agtagaaata gaatgggaag
    83581 aagttaatgc aggagaggca gttattgaag agtatggtac tccacttcct gaatatatta
    83641 tagatagtat aaaaaagaac aaaatagcta taaaaggccc aattactact cctgtaggta
    83701 aaggatttag gagtgtaaat gtaactttaa gacaggcatt agatttgtat gtcaacttaa
    83761 gacctattaa aagttttaag gggataaaat caagatatga agatgttgat ttagtggttg
    83821 taagagaaaa tacagaagat ttatatgctg gaatagaaca taaaataggt gattatgcag
    83881 ctgaaagtat aaagataata acaagaagtg caagtgaaag aatcgttgat tttgcatgta
    83941 actatgttaa agataataag agaaaaaaag ttacagctat acataaggca aatataatga
    84001 aaatgtctga tggattgttt ttagatgtgt ttagagaagt tgcatcaaaa catggtgtag
    84061 aatatgatga tttgattgta gatgcagcag ctatgaactt agttttaaat ccagaaaatt
    84121 atgatgtaat ggtaatgcca aatctttatg gagatatact atcagattta ggtgctgggc
    84181 ttgttggagg tttaggtata attccaagtg caaatattgg taaagattgt gcgatatttg
    84241 aagctgttca tggaagtgct ccacaaatag caggtcaaaa taaggctaat ccaacagcac
    84301 ttattcaatc atcagtaatg atgcttagat acttaggtga atatgaaaat gcacaaaaaa
    84361 tagaaacagc tttagaaaaa gtatttcttg aaggaagtaa attgactgta gatttaggtg
    84421 gctcagcttc tactacagag tttgcggatg aggtgtgtaa gtatattgta tagattttat
    84481 ttagggaaaa agtaaaatat agattgaaga aaagaggctt tctcaaaata gagataagcc
    84541 ttttttattg gaatgataaa atatatttga ttttatacaa aagagagttc ctcataaacg
    84601 aaaaagttaa ttttgggata tccattttaa ttttaaaatt aattgattaa tacgcaaaga
    84661 aagattaaat aaatttatta tttttaattg aactttcaac caaaatatgg taaaatttaa
    84721 aaagttgaac tttcaactaa aaatgaaaat attgattatg tgaaattcta taaaacagaa
    84781 actatttgac tttagccatg gtagtttcag tggaggtgtg tttgattaag actttagata
    84841 gtaatatatt aagagaagta ggtactttat ctagagcagt aaattcaata aatgatatta
    84901 agtacaagga attaaagtta caaaaaggac aatttacatt tttgacaaga atctgtgaaa
    84961 atcctggtat aaatcttgtg gaattatcaa atatgttaaa ggtagacaag gctacaacaa
    85021 ccaaggctat acaaaaatta ataaaggcag gatatgtaga taaaaagcag gataagtttg
    85081 ataaaagagg atataattta actccaactg ataaatcttt ggaagtttat gagttgataa
    85141 ttgaagaaga gaatagaagt atagagatat gttttgataa ttttacagat gaagaaaaac
    85201 aagtggtaac taagttatta gaaaaaatga gcaaaaacgt agaaaatgaa tggtttaaag
    85261 taaagagata gtaaataaat acattaactt aaggagatat ttttatgatt agaaaagcga
    85321 atatgaatga tttagaaagc attatgaaaa ttataaaatc tacagtggaa gaaatgaaga
    85381 cttataataa tacacaatgg gatgaaaact atccattaga aaaagacttt gtttcagata
    85441 ttaagaaaca agatttatat atttatgaag tggatggaga agtagcaggg tttatatgtc
    85501 ttaattatga agagccagaa gaatatttag gcttaaattg gtcatctaat aaaaaagcaa
    85561 tggtaataca tagaatggct gtaaatccaa actttagaaa gacaggaata gcatctaagt
    85621 tagttgattt tgctgaaaaa ttagctgtag aaaacaatgt atcatactta aagagcgata
    85681 catattcaat aaactcaaaa atgaatttat tacttacaaa gtgtggtttt ataaaaatcg
    85741 gagaaatgag ttttttagga aaggagaaat ctttctactg ttatgataaa atattataaa
    85801 gagcatttat aatacaaggg gtaaataata gattttcagc attagtaagg gcataatata
    85861 acctagtata tgctattatg aaagggatga tttatatgat tggatttcta aagaaaagaa
    85921 gaagtattag aaaatacaag gatgttgaag tagaaaaaga aaaattagat aaaatattaa
    85981 aagctgctct tttagctcca tcatcaaagg ggcttagaac atgggaattt atagtggtag
    86041 atgataaaga aaagctaatt aatttatctc aatgtagaac taaaggtggt ggatttttct
    86101 taaaaaatgc acctttagct attgtaatta ttgcagataa agaaaaaaat gatgtttgga
    86161 tagaggatgc aagtatagct gcttcataca tacaacttca agctcatgaa ctaggtttag
    86221 gttcttgttg gatacaagta agaaatagaa tgcatgatga taatatagaa gctgataagt
    86281 acattagaga agaattaaaa gtacctagca agtacagtgt agaatgtata atttctatag
    86341 gatatcctga tgaagaaaag aaagcatacg gtgactctga tttagactat aaaaaggttc
    86401 attttaacaa cttttagtat ataatatgtt gtattaagac attatatttt tttctattgt
    86461 taatatatac ttaaaattgt aaaaatatat ctgaatttta ctaacttatc taggggttat
    86521 gtacaaggat tttaaagata aatatagaaa ttaatgttta taatcgatac ataacttgag
    86581 taacaaaatt taaggaggtt aaagtatggg tatatttaaa acaaaaatgg atgaggactg
    86641 gaaagtaaac tacattaaag agtttaatga aatgagagat tcttatgaga gtaaacttca
    86701 aaaaaaacag tttgaggtag atagtttgaa atcagaattg gatagactaa gaagctataa
    86761 aaatagcctt aagccaaaag aaaaacaaat tactgatgat gatataaata atataaagag
    86821 tttaagaaga gatggcttaa gctataaaga aatttcaaat caaacaagtt ggagcaaagc
    86881 aactgtaagt agggtattaa atggacttta cgattagcat atacatgggg tgatttaaat
    86941 tgggatgaag tatagttaca aaaaatgcat aatagattct attttattga tgtttatagt
    87001 tcaaatatta aggatgattt tgaattatgt acttctaagt caatttgaat ttactcttga
    87061 aaattttaat attataaact taatttcttt tacattagtt ggtttatcgt taattttatt
    87121 tttaaaagat aattctttgt ataacaaggt tagaaataga aaaatcacag aagcttttga
    87181 agaaaataaa aacaatatac ttattgaaaa gtgtaagctg atactttttg ttgtggtttt
    87241 atctttagca ataattgtaa cttattgtac taagggatat gtacttttta atgtaactat
    87301 gatgactttg tctgtattga tagtcccaat atttgaagag ttatttttta gagaatatat
    87361 atggaactat ctaagtaatt ttataaagtc aaagagtaaa attatctgta taacatctat
    87421 actatctgga atttataata taggatacat agatgttata agaaattatg taatattgta
    87481 taacaattca agctacacct ttgaagttat tatttcaaaa attatgatag gtactgtttt
    87541 tggtattgta cttggattag ttaagtatag gtttagagat gtagggtttt gtatattatt
    87601 gaggagctta tttgctatat ttattaggta gatagtataa tcggtttata aggttgtttt
    87661 aaatttaatt ttaaatcaac cttattttat ttgtgtttta taaagcactt atatattaat
    87721 aactaataaa tttaataaaa attatttgaa tatttttaaa atatataaat atgtattgac
    87781 atataaatat tatgaattac aatttatata aactaataaa aattaaataa tattaatcaa
    87841 cttattgaat ggaggaataa aaatgaaatt tgtgactttt tgtagtagca atgaagaaaa
    87901 aataggtgta tttaattcag aaacaaatag tatatatgaa attaatagtt taggattaag
    87961 taaattatat actgatatga atgattttat tgaaaacgta tctacaggag atttagaaaa
    88021 aataaaaaac aattcatttg aaaacgcaaa gtgttataag ttagaagaag ttaaattatg
    88081 ttccccaatt gtaagaccta aaaaagatat tatatgttta ggtctaaact ataaagacca
    88141 tgtcaatgaa atcccagatg gagttataaa aaacgtagtt atgccagatt atccaattta
    88201 tttttctaag agagcagaca aaataattgg agtggatgat aagataagct tacatggaga
    88261 tttggtagag aagttggact atgaatcaga acttgcagta atcataggta aagaaggtat
    88321 aaatatatca aaagaagatg cttatgaata tatatttgga tatacaatag taaatgatat
    88381 aagtgaaaga gcacttcaag ataaacatgt tcaatggttt agaggaaaaa gcttagacac
    88441 acatacatct atgggacctt gtatagtaca taaagaagaa tttgaacatc ctttaaaatt
    88501 agatataagt agtgtagtaa atggagaagt aagacaagat tctaatacag agtactttat
    88561 atttgatata cctactataa taaatgattt atcaagagga atgactctaa agccaggaga
    88621 tataatttca actggaactc cagcaggggt tgctatgggg atgaatcctc aagtatattt
    88681 aaagcatggc gatatagttg aatgtaaagt cgaaggaata ggagttttaa aaaatatagt
    88741 tgattaatgg ataaatatgc catataattt tattagtacg aataatttaa ttaatatagg
    88801 attaatcaaa cttatgatta atttattata gagagggatg agtatatggc aagagaacta
    88861 gaattaaagt atggctgtaa tccaaatcaa aaaccatcaa agatttatat gaagaatgga
    88921 gaacttccta tagaggtatt aaatggaaaa cctggataca taaatttttt agatgcattt
    88981 aatagttggc aacttgtgaa ggaattaaaa gaagctacag gtcttccagc agcaacttca
    89041 tttaaacatg taagtccagc aggagcagca gtaggggtac ctttatcaga tactttaaag
    89101 caaatatatt ttgttgatga tttagagctt tctccattag cttgtgctta tgcaatggca
    89161 agaggagcag atagaatgtc ttcttatggc gattttatag cactttcaga tgtatgtgat
    89221 aaggagactg caactattat agcaagagag gtttctgatg gtataatagc tccaggatat
    89281 acagatgaag cccttgaaat attaaaagga aagcgtaaag gtaactataa tattgtaaaa
    89341 atagatgaaa attatactcc tgaacctatt gaaacaaagg atgtttatgg aattactttt
    89401 gaacaaggta gaaatgaaat attaataaat gaagacctat taaaagatat tccaactgat
    89461 aataaaattt ttacagatag tgcaaaacgt gatttaatta tagctcttat tacattaaaa
    89521 tatacacaat caaattctgt ttgttatgct aaagatggac aagtaatagg ggtaggtgca
    89581 ggtcaacaat cacgtattca ttgtactaga cttgcaggta acaaagctga tacttggtat
    89641 cttcgtcaac atcctaaagt attaaactta aaatttaaaa aggatatagg tcgtccagat
    89701 agagataaca ctattgatgt atatctttct gatgattata tggatgtgct tgctgatggc
    89761 atatggcaaa acttttttga agaaaaacca gagcctctaa ctggagaagg aaaaagagca
    89821 tggcttaaaa ctttaacagg agtagcactt ggttcagatg catttttccc atttggagat
    89881 aatatagaac gtgcaaaaag aagtggggta agttttatag cacaaccagg tggttctatt
    89941 cgtgatgata atgttatatt aacttgtaat aagtataaca tagtcatggc atttactaaa
    90001 aatagattat tccatcatta aaatactgaa agtataaaga taatatagat taagtaaaaa
    90061 tctacaacaa gttttgttgt agattttttt atttgctgta taattttaaa tagaacttta
    90121 tttttagata ttcaatttgg aggttgatat ggctttaaat ataagaaact atagcctatt
    90181 atgtaatcaa ggaacagcta aatttaatga agatgtagtc ggtataaatc catttggggc
    90241 atgggtttta gatggtgcta caggacttaa tggaaaaaat ttagtgtcaa ctgaaagtga
    90301 cgcaaggtgg tatgttcagt ggtggaatag gtatttatat aaaaatataa ataaagaaga
    90361 atcattaaag agtattatta atactggaat aatagaagta aaaaaagagt atgaactaag
    90421 attaaatggg tttaaggttg aaaaattaga tttaccatct agttctatag ttgttgtaaa
    90481 atttcatgaa aataaagtag agtatttttt attaggagat tgtgctttgt ttattaaaaa
    90541 tggagattcc aaagttataa aagataggag tatttgtaaa tttgataata ctgtatttga
    90601 tgaaatgagt aaactttcta acttggaaga gatggctttt gatgagatta gaactagtgt
    90661 tatggataca atagtaagca atagattgaa gaaaaataca aaagagggct attggatatt
    90721 ggattttgat gaggaagctg tggaaaattc tatatatgga tacattgaaa taaaaaaaga
    90781 ttttcaattg atgctaacga gtgatggttt tacaagtgca tgtgatagat ataatctaat
    90841 aaaagaagaa gaattgatac gtatagcaga aaaatttggt ataggatata tacataataa
    90901 agtaagggat tttgaagata atgactataa agcggttaaa gtgccaagat ttaaagtaaa
    90961 agatgattca tcttgtttat atttagatat atataatgat tagactgtat aaaactattt
    91021 aattttagaa aggaggcaag tgaaaagtga aaattcttca tataataaca caaaaaccaa
    91081 atagtacagg tagtggtata tatttgtctg gtatgataaa agggttcgaa aaaatcggtc
    91141 ataagcaagc tgtaattgca ggtatagatg taaatgatga tgtaaattgt tttccaagtg
    91201 aagtaagttt ttatccagta aagtataatt gtggggagtt aaattttcct gttgtaggta
    91261 tgagtgattc tatgccatat gaaagtacaa gatataaaga tttaaatata gacatgataa
    91321 atagattgaa atatcaattt aaagtaaata tagataaggc tatgaatgat tttaaaccag
    91381 aacttataat atgtcatcat ttgtacctct taactgcatt tgttagggaa atggtaaaag
    91441 atataaaggt tatgtctatt tgtcatggaa cttgtttaag acagttaaat accattgatt
    91501 tagagaaaga atacataata gcaaatataa ggaaattaga tttaatattt gctcttcatg
    91561 aaaatcagaa atatgatatt ataaagactt ttggagtaag tgaaagtaaa gtagttgtaa
    91621 ttggtagtgg ttataatgat gatatatttt ataataaaaa ttataaaata aaggatgata
    91681 aaataaaaat agtatttgca ggtaagatat gtaaatcaaa gggactgatt ccatttataa
    91741 aagctatatc taaattaaaa tatagtaaag atttaataga agtcaatttt gcaggtactg
    91801 gaagcgatat cgaatcatat aatgagatag ttaaactggc aagtaagtct ccatttaaaa
    91861 tgaatttcct aggaaagtta gaacagagag atttagctga gctattcaac aggtcacaaa
    91921 tatttgtgtt accatcattt tatgagggat taccagttgt agttttagaa gctttatctt
    91981 gtggcacaga tgtaatcact actgatattc ttggtgttaa agagtggatt ggtagtgaga
    92041 ttaataattc tggaaagata gaatatgttt ctctaccttt tatggagaaa gaaggtattc
    92101 caaaagatga agagttatat gattttgaaa ataatttgta taatgcaata gattctaaga
    92161 tacaatcttt attgaataac tcaaataaga aaacatctgt agatatgtca aaaaaaacgt
    92221 gggatggctt agcatataga ataaatgaag ttattttaat ggatgaattg tgtttagtct
    92281 aaaattattt aaattataaa aaagtgtaac tatttttaca ctatttttaa atgattttat
    92341 attatactaa tactaaatat atttgtttta gggaggtaat ttatgaggat tagtaaaaag
    92401 gtattggcgt taggtatttc agcattactg ttaagtgtta gttttccaac atcaataaac
    92461 gcactagata agattgaaaa tattcaagga gtagataaat atgaaacagc tgggcttatt
    92521 tcagataagc aagattttac aacagcagtt cttatcaatg cagactctac aatggtagat
    92581 gggattgctg caagtggtct tgcaggagta aataatgcag ctattttatt aactaataag
    92641 gatgatatac cagaagcaac acttcaaaga ctgaatagag ttactaagat atatgtaata
    92701 ggtggagaaa attctataag taaagatgta gaaaaaatgt tacttatgag aagaatgcaa
    92761 gttataagaa ttgatggtgt agatagagta gatacaagtt ataaaattgc aggtgaaata
    92821 gaaaaaatta aaaacagtga taagatgttt ttagtaaatg gatttaagga tgaagctgat
    92881 gcagtaagtg ttgcatctgt tgcttataga gatggagctc ctataatatt gacaaaagat
    92941 ataccttcag cagaagaaga cacagactta gacccatggt ttggagtttc tcctgttcca
    93001 gtatatgcta ttggaggaga gtctacatta agtgattaca tagtgagcag atatagagca
    93061 actagaattg gtggtgttga tagatatcaa actaataaaa atgttattga aaagttctat
    93121 aatggagcaa aagagttcta tataacaagt ggagatgatt tagtttatgc tttagttgca
    93181 tcaccacttg caaaaaatgc tcctgttgtt ttagtttcaa ataaaagtga taagagtata
    93241 ttaagtggag ctagtaaagt aacagcaata ggtataagtg ataagagtat tatagagcaa
    93301 tgtttggatg ctgtaaagaa gtaatggagt gttattagta aaatgaatat atacattgaa
    93361 aattagtaga ttgttcattt tataatggta taaaatatat gggaagaggc tatcaaatgg
    93421 agataagcct ctttttcatt gttaaaatta tgaaaagata ctttatttta tataaaaaag
    93481 tatcttatga actaaatgtc tattttgaga cactatctac ttttcttata ttatattatt
    93541 ttttatatgg aataaatttc ataagtatta tcttccttta atttttctaa ccaaaccatc
    93601 tctaaaatat ctagttcttc taaatagtct ttctctgttt tgttatcatc atgttttata
    93661 agttctaaaa cttcaaatgt aaatgctttt tcaccatatt ttttccattc attatttaat
    93721 tcttttatca tacatgagcc agcaccaagc tgaaatttga gagagttaaa tttgcttttt
    93781 atgtcattac tttttccaag gtaaatcttt ttagtaatat cattttttat tatgaataca
    93841 cctgtgtcaa atttcatttc tttgtataat tgttttaatt cacgttttct atccatgatt
    93901 ttagatacct ctctttataa ttgatatgta atatgtaagt gtaaaaatat attacatatc
    93961 aattataaag agattaattt tatatgtaaa tagtttttat aaatttaatt atgaattagt
    94021 catcaataaa caagaaattt agctgtaaaa atccattata aaggctatta taaattttaa
    94081 tatgctaaaa atataaaaag aatagttgac agtgtagaaa atatggaata aactaaaagt
    94141 gtaatagtaa tatgaagtta tatattacat tgaaaggtgt gaatgattat tatgaataaa
    94201 aaaatagaat taatagggaa ttttgcaagt gattggatta ggtatagtga ttatgaatat
    94261 aaaattactg aagaagatga attatatata gttccaacag aagatgctgt gtttaccatg
    94321 tataacccat ttgatgtagc agatgatata atagtagata taattcgcat aggacaagag
    94381 gcattacaag atatatcaaa agagacaaaa gaaatgaaac taaagaaaga agtacttgaa
    94441 tttgtaaaaa agtatggatt attgggttta atatattcaa gtgtatataa tagagatata
    94501 gttggagaag aaagagtact gatgattgaa aagaattata ttacaaaaga gaatatattg
    94561 agtacagatg aatatgtaaa catgtttata ccatttgcaa gtgatgaaga tgtgtatttt
    94621 aaaaagtata gaaggggtat agatgtatca aagagagaag aatctccaaa gttttttgga
    94681 aagagaccat tgattttaga tttagtattt tcaaagttct acactgaaca actagattgg
    94741 attgtaagtt ttgctaaaga tatgtgtaag cattttaatc aaatttgtgt atataaaaat
    94801 acatctaatc tattaactga aagtgttact attatgtctg gagggtttaa tcctcaaaag
    94861 ataggatttt ctataagcca attagataaa ccaattattg catgggagtt tgattctttg
    94921 aaaacagcta ttgagactat ctatgccttt gcaattacaa gtgaaccttc ttctttaaat
    94981 aaatgcaagt actgtggtaa aatttatatt cctacaaatt ctaaatctca atactgttca
    95041 ccttcttgta gaaattgctc aaatgtaaag aaaagtagaa gtagagccaa aaaagataaa
    95101 taaaattaat aaatatatca ttgtttagat tttagtaaat aactactgaa ttaaaagttg
    95161 ttatagaaaa ttatatatct aaatgatggt atttttttgt tgagaaaatt gaaaagttta
    95221 attgagatag taattttgag ttgacaaaaa ccacttttaa cactactatt ataagtggtt
    95281 ggtaaaataa tatacattaa tttaagtata gcataaaaaa caaaaaaagt caatggaaaa
    95341 aataaaaaag gagaatttaa aaatgatatc acctattatt ttgagttcta taaatcagaa
    95401 tttaaaggaa atagaaagaa atgaactgct tgaaactaat atagaatctg gagattatgg
    95461 tctagctctt tctgaatctg atgtaaaaga tataataaat tcgagagata atactttaaa
    95521 ggggtatgga agaatagaat tagatataaa agttacaaaa cagttaatag aaaatatata
    95581 tacatcacaa tatacaaatg tggacaatta tttagaggct attaatgata tgcaagaaat
    95641 tttttattat ttaaaaaatg aaactgatga caagatatgt gatgatgaga ttatagaaat
    95701 actgggtgaa ttttatgaaa aattttcagg caatatggac aatgtaagag gagaagcaga
    95761 cgaatttgca aagaaattta aatttggaga agtttaatat atgataggag agattttgta
    95821 tgttaaataa tttaagtaat attaatataa acgaaaataa tttaataaag aaccaatatt
    95881 ccatatctct acttaaggaa tgtctaaatt gtaaagtgat agatgaaaga gaagtatata
    95941 atatacaaca agaagtatct ctaatactta tggacttgat taaaaaatat acaaatggtc
    96001 aaagcacatc agtaaaaaca gaagttgccg aaaaactgtt gatttcaata tggtatgcta
    96061 ttgatgcata tataaataag cttggagata tagaaaaaag agttgtggag ttgactgcta
    96121 agaatgttaa aaaagtgtac cttggaggca ttgaaatatt agaggaagag ttagttaggc
    96181 taaaagattt ttataaacta atgatgagta gaaaattgga tactaattca atagcatata
    96241 atgatacctt gatggagtta tcaagtttct ttaaaagtta tattgtaaaa tttgaagctc
    96301 aggacgttcc agtaagtata gattatccat tggcactaga tgatatggat gttaagggta
    96361 tttattatgt gaagaattat attgagagta tagatataga aaatagattt tgtaacctat
    96421 ttaagaaaaa agatagagaa aaattatttt atgactatgg gatgacttat aaaatagatt
    96481 gtgatgttat acttgtaaat ttatttgaac ttattatgaa taattgtatt ttttctacta
    96541 ttttaggaaa tgaagtgact aatttagaaa tttcaaaata tgagtatgaa tttttagaaa
    96601 aacaatttaa aaatatgtac aataatatta ctgaagataa agttatagac tctgaagaaa
    96661 gtaatataat tgaattgatt gaagtagatg atagttttaa cactgaagta gatagtaatt
    96721 tggattataa tgattttgaa gaaattaaca gagaaattag aataaataaa aaaataactt
    96781 tactacttat ggaagcaatt gaagtattaa taaaaagatt aagcatagaa gatgaagatg
    96841 taataagata tattaaaaaa tatgaaaaga tatttattga atctgtgcta agctcaataa
    96901 aaagtaacac ttttaaaagt atggtaactg tgagtaaaaa taaaaaggaa cacttagaag
    96961 attatattgt tgatgatgaa agtaaattgg atgatgaatc gtttagagag atattcaatg
    97021 agatattaga tagtacatct ataattgaaa aaataagaat aataaaggaa aatatcaatg
    97081 ctaaaaaaga ctttatcgat attcttgaat ctgaatgttt atttggagaa gagtatttaa
    97141 tgttgtttgc atcattaagt gaattagaat tggcaatatt gggtagtgta gtattttatg
    97201 aagatattag aatgagagaa attaatatat tagaatttat gttaaatgag aaaactgaaa
    97261 ctactttatg gaagatagag tacattaaat ttatgaagag gcaaagtgaa gataagatat
    97321 actccataga agagcatatg aataaaatta attaacaaaa aattgtgaat aaatagaatg
    97381 ttagtatata atataatctg taaagcatat caaaaataca tatatttgga ggaaaattat
    97441 gaaagagtat atcataaata atgttgaaga aataagagaa gaattaattg atttatctaa
    97501 gaaaatatgg gaaaatccag aattagcctt tgaagaaaag tatgcaagta gcattcaaaa
    97561 agaataccta aagtcaaaag gatttaaaat tgaagaagta gaaaatttac ctactggatt
    97621 tatagcaagt tttggagagg gtaaacctgt gattggcata cttggagaat atgatgcttt
    97681 accagagcta tcacaatgtg taagtgcaga aagaaagcca ttggtagaag gaaaagctgg
    97741 acatggatgt gggcacaacc tgttgggtgt agcaggtgta ggagcagttg tttctataaa
    97801 aaaattaata gaagaaaata aatttaatgg aacaataaaa tattttggtt gtcctgctga
    97861 agaagaaggt ggaggaaaga cagttatgtg tataaatggc tgttttgatg atgtagattg
    97921 tgcatttaca tggcatcctt ttgatataaa tgcaccttgg agaggtggaa gtctggcaaa
    97981 cttatctgta aaatttaaat ttaaagggat aacagcccat gcagctcaag ctcctcataa
    98041 tggtagaagc gcacttgatg ctgttgaaat tatgaatgtt ggagctaatt atttgagaga
    98101 acatgttatt gactctataa gaatgcacta tgttataact aatggtggtg gaagacctaa
    98161 tgtagttcct ggatttgctg aaagttggta ctttattaga ggtaaaaaag caaaggatgc
    98221 agaacacgtt cttgatagat taataaaagt agctcaagga gcagcaatga tgacagaaac
    98281 tgaaatggag tataaggtta cagatggaat atatgactat ataccaaacc aatgtttgac
    98341 tgatttagtt tatgacaata tggtttttgt tggttgccct aaaaatactc ctgaagaaga
    98401 agaatttgca aaaaagttgt gtgatactct tactagagaa gaaagattag gtgtagcaac
    98461 atcattacaa aatgataaat ctattgtaga aagctatata cacaaggaaa tagttgacgg
    98521 tgacaaagat aaaggactag ctggttctac tgatgttgga gatgtaagtt atgtaatacc
    98581 agtggctcaa tttgcaatgg cagcttggcc tgttggaatt gcaagtcata catggcagtc
    98641 atgttcatca gcaggttcaa atataggatt ttctgctatg ataaattcag ctaaagtact
    98701 ggcttgtagt gcttatgatg tatttatgga tactaaaatt attgatgaag caaaaattga
    98761 atttgataaa tcattagatg gacaaaaatt taaaccattg gtataatttt gctaataaaa
    98821 tatttctggg gggaatagct atgagagaaa aagttgaaaa agtgcttgag gaaaagataa
    98881 aaccagtatt acaaagagat ggtggagatg tagagcttat agatgtaaat gaaaatggtg
    98941 tggttttagt tagactacaa ggggcatgta gtgggtgtcc aggagtgact atgacaatca
    99001 aagctattat tgaaaatgtt ttggtgagtg aagttccagg agtaactcaa gtattaggtg
    99061 tttaatagtt agcgtttatt aaatgtatgt tatacataag tatttaataa agaagtaaaa
    99121 aaaatagtga agcaatatat atgaaaaagt atgagaaaga taataaaaca ttatagaaat
    99181 aatgaaatat ttcatatgta tatgaagaaa taagaaaaaa tagtgaagca atatatatat
    99241 gaaaaagtat gagaaagata ataaaacatt tatagaaata atggaatatt tcatatatac
    99301 atatgaagaa atagtaaaac aatatatata tgaaaaagtg tgagaaaata ataaaatact
    99361 atagaaacaa ttaaatattc tatataggta ttaagaaaca tgaaagaaat aatggagtat
    99421 tataaataaa tatgtaaaag tgtgaaagaa ggatgtagat aaatttgtct tatacaaatt
    99481 tacctacagt atttcttaca cactttttat tttactatcc agccatacca ataaacatac
    99541 ctataaaata tggaactaac catatagtcc atacaactat actaaactta tgaaagaatt
    99601 ttttcttttc ctcatcatct ttgtatagga caaaagtagc ccaacttgca tgaaaaagca
    99661 taagcacaat tgcaagaaga cctgtaatac tatgaaggtt ttgtgataaa gcagatttta
    99721 cttcaaaagt atggctgttg gctatgttac tcattgtaaa tgttcctaaa gtatcaaata
    99781 taaaaccaag ccaaaatata attacatgtt tcttttttaa aatttttgcc tttctttctc
    99841 caaatacacc tatagtgtag aaaattaaag ctgatgttat aaatactatt gcaagtatta
    99901 atttataatt cataattatc tctcctttac ttttgccaat atatttctaa gattttttac
    99961 taagtcactc aattcgtttt catcacaatt tttaaaaata tcatcaaaac tttcttgcat
   100021 tttaatttta aaatttgtgg caaattcaaa tcctgttgtt gtaaacttaa cgtatgtatt
   100081 tcttttatca ttagatttct tgaatttttc tatatatcca atctgttcta atctgctgat
   100141 tatgcctgaa accgtacctt tagctaaaga catttcatca catagttgtg atattgtaag
   100201 ttcttgatta tgagctatca gttttataac tataatctgt tggtgtgtta atccattttc
   100261 tttaaaattt tcttctactg tgtacatagt tttagaataa agttctttta agagcatggc
   100321 tattctaaaa cagtcataat tacttttcaa taaaatcacc tcttaaatgg tttgcataca
   100381 aactaatata atatactttt cttatatagt caacctaaaa ttttataatt ttatagaaaa
   100441 taatgaagaa tagaatataa aaattttatt ttaggtataa ataaaataat ttgatgaaat
   100501 tttaacaatt tttaaaaag
//
LOCUS       DAYAKB010000003        98172 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.003, whole genome shotgun sequence.
ACCESSION   DAYAKB010000003 DAYAKB010000000
VERSION     DAYAKB010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 98172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98172
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.003"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            489..3131
                     /gene="adhE"
                     /locus_tag="ACGI3L_000261"
                     /gene_synonym="adhC"
     CDS             489..3131
                     /gene="adhE"
                     /locus_tag="ACGI3L_000261"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFG9195999.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3491..3832)
                     /locus_tag="ACGI3L_000262"
     CDS             complement(3491..3832)
                     /locus_tag="ACGI3L_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196000.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(3859..4530)
                     /locus_tag="ACGI3L_000263"
     CDS             complement(3859..4530)
                     /locus_tag="ACGI3L_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196001.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4542..7118)
                     /locus_tag="ACGI3L_000264"
     CDS             complement(4542..7118)
                     /locus_tag="ACGI3L_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9196002.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            7326..8261
                     /locus_tag="ACGI3L_000265"
     CDS             7326..8261
                     /locus_tag="ACGI3L_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9196003.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            8280..9017
                     /locus_tag="ACGI3L_000266"
     CDS             8280..9017
                     /locus_tag="ACGI3L_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9196004.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(9202..14259)
                     /locus_tag="ACGI3L_000267"
     CDS             complement(9202..14259)
                     /locus_tag="ACGI3L_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HFG9196005.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(14284..14703)
                     /locus_tag="ACGI3L_000268"
     CDS             complement(14284..14703)
                     /locus_tag="ACGI3L_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196006.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(14937..15188)
                     /locus_tag="ACGI3L_000269"
     CDS             complement(14937..15188)
                     /locus_tag="ACGI3L_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196007.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            15277..16008
                     /locus_tag="ACGI3L_000270"
     CDS             15277..16008
                     /locus_tag="ACGI3L_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HFG9196008.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            16067..16978
                     /locus_tag="ACGI3L_000271"
     CDS             16067..16978
                     /locus_tag="ACGI3L_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9196009.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            17029..17841
                     /locus_tag="ACGI3L_000272"
     CDS             17029..17841
                     /locus_tag="ACGI3L_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFG9196010.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            17950..18642
                     /locus_tag="ACGI3L_000273"
     CDS             17950..18642
                     /locus_tag="ACGI3L_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9196011.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            18729..19670
                     /locus_tag="ACGI3L_000274"
     CDS             18729..19670
                     /locus_tag="ACGI3L_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196012.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            19707..20864
                     /locus_tag="ACGI3L_000275"
     CDS             19707..20864
                     /locus_tag="ACGI3L_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HFG9196013.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            21016..21576
                     /locus_tag="ACGI3L_000276"
     CDS             21016..21576
                     /locus_tag="ACGI3L_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFG9196014.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            21604..22095
                     /locus_tag="ACGI3L_000277"
     CDS             21604..22095
                     /locus_tag="ACGI3L_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196015.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            22324..22875
                     /locus_tag="ACGI3L_000278"
     CDS             22324..22875
                     /locus_tag="ACGI3L_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9196016.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            22961..23893
                     /locus_tag="ACGI3L_000279"
     CDS             22961..23893
                     /locus_tag="ACGI3L_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFG9196017.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            23948..24811
                     /locus_tag="ACGI3L_000280"
     CDS             23948..24811
                     /locus_tag="ACGI3L_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFG9196018.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            25058..26920
                     /locus_tag="ACGI3L_000281"
     CDS             25058..26920
                     /locus_tag="ACGI3L_000281"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9196019.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            26923..28389
                     /locus_tag="ACGI3L_000282"
     CDS             26923..28389
                     /locus_tag="ACGI3L_000282"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9196020.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASAIATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            28413..29249
                     /locus_tag="ACGI3L_000283"
     CDS             28413..29249
                     /locus_tag="ACGI3L_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9196021.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            29815..31398
                     /gene="asnB"
                     /locus_tag="ACGI3L_000284"
     CDS             29815..31398
                     /gene="asnB"
                     /locus_tag="ACGI3L_000284"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFG9196022.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDRYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(31463..32059)
                     /locus_tag="ACGI3L_000285"
     CDS             complement(31463..32059)
                     /locus_tag="ACGI3L_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HFG9196023.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEIAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(32086..32613)
                     /locus_tag="ACGI3L_000286"
     CDS             complement(32086..32613)
                     /locus_tag="ACGI3L_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HFG9196024.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            complement(32975..33973)
                     /locus_tag="ACGI3L_000287"
     CDS             complement(32975..33973)
                     /locus_tag="ACGI3L_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HFG9196025.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            34650..35849
                     /gene="hadA"
                     /locus_tag="ACGI3L_000288"
     CDS             34650..35849
                     /gene="hadA"
                     /locus_tag="ACGI3L_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HFG9196026.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            35888..36688
                     /gene="hadI"
                     /locus_tag="ACGI3L_000289"
     CDS             35888..36688
                     /gene="hadI"
                     /locus_tag="ACGI3L_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HFG9196027.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            36703..37929
                     /gene="hadB"
                     /locus_tag="ACGI3L_000290"
     CDS             36703..37929
                     /gene="hadB"
                     /locus_tag="ACGI3L_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HFG9196028.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            37929..39056
                     /gene="hadC"
                     /locus_tag="ACGI3L_000291"
     CDS             37929..39056
                     /gene="hadC"
                     /locus_tag="ACGI3L_000291"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HFG9196029.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            39104..40237
                     /gene="acdB"
                     /locus_tag="ACGI3L_000292"
     CDS             39104..40237
                     /gene="acdB"
                     /locus_tag="ACGI3L_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative isocaproyl-CoA dehydrogenase AcdB"
                     /protein_id="HFG9196030.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            40270..41055
                     /gene="etfB"
                     /locus_tag="ACGI3L_000293"
     CDS             40270..41055
                     /gene="etfB"
                     /locus_tag="ACGI3L_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HFG9196031.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            41074..42111
                     /locus_tag="ACGI3L_000294"
     CDS             41074..42111
                     /locus_tag="ACGI3L_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFG9196032.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            42594..44225
                     /locus_tag="ACGI3L_000295"
     CDS             42594..44225
                     /locus_tag="ACGI3L_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9196033.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(44360..45286)
                     /gene="fba"
                     /locus_tag="ACGI3L_000296"
     CDS             complement(44360..45286)
                     /gene="fba"
                     /locus_tag="ACGI3L_000296"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0030388 - fructose 1,6-bisphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HFG9196034.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            45616..45945
                     /locus_tag="ACGI3L_000297"
     CDS             45616..45945
                     /locus_tag="ACGI3L_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HFG9196035.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESIDLAFTVFEKEKY
                     YENGEHF"
     gene            45945..46667
                     /locus_tag="ACGI3L_000298"
     CDS             45945..46667
                     /locus_tag="ACGI3L_000298"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFG9196036.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            46694..48055
                     /gene="rlmD"
                     /locus_tag="ACGI3L_000299"
     CDS             46694..48055
                     /gene="rlmD"
                     /locus_tag="ACGI3L_000299"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFG9196037.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVLL
                     RRK"
     gene            48447..50516
                     /locus_tag="ACGI3L_000300"
     CDS             48447..50516
                     /locus_tag="ACGI3L_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9196038.1"
                     /translation="MQLTKIILSNYRCFGEEPTTIEINNLTGFIGHNSSGKTALLSAL
                     MKLFGEKSSDRIIERSDFHIPESIDPDSISKNELYIEAQFEFPELERGKDSISIPVFF
                     KNMVVSEPGGKPYLRIRLEANWEKSSNPEGSIDSNVYYITSTTEEINPEDKRNIKRYE
                     LDQIKMIYVPAIRRPDEQLKNVSGTIISRLLNGISWSEQTKARIKTKASETEEIFFEE
                     KGVESLKKSLETQWNSYHKDIRYSNPKINFNSTDLETILKKVEVTFSPTGTHRDYRVE
                     ELGDGLRSLFYLSLVNTFLEIEEEILKSINDGKEEDIFTLIPPVLTIVAVEEPENHIS
                     PHLLGRVVEKLNFISTKENSQTILTSHSPAIVKRIEPTDIRYFRICKEYECTKVKSII
                     LPNEEKEAEQFKFVKESVLAYPELYFAKLVVLGEGDSEEIIIKQMIELKAESVDSSEI
                     SIVPLGGRHVNHFWRLLNDLEIPFITLLDLDRERDGGGWGRIKYAIQQLINIGHDKNV
                     LLYTCEGISQDNEFKEMHTWDVTDTENMAKWIEMLKGYDVYFSAPLDIDFAMLQSFKD
                     KYISALTSAEGPRIKDHGKIQDIVINEDAEDESLKAAYKDRIDSDIKSTLKQEGGDGS
                     TYTEGEKELMIWYSYFFLGRGKPTTHLSLFSNNTDIDFESFPYCLKEFVNSIIEKMID
                     DSGGGRK"
     gene            50513..52378
                     /locus_tag="ACGI3L_000301"
     CDS             50513..52378
                     /locus_tag="ACGI3L_000301"
                     /inference="COORDINATES: protein motif:HMM:NF012789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFG9196039.1"
                     /translation="MKRNWVSKEDWSPAAGFRLEVEAMNTVINDKNTLVVAGPGAGKT
                     ELLAQRACFLLETNTCRYPKKILAISFKKDAAENLKERLELRCGKELASRFESKTYDA
                     FAKEIVDRFRNSLDEAYRPLNNYNIAENRDVRRAFEIAGLNFRGNQTEFNKVYGNKLS
                     INKLPLHTDFVDKIFIDAWNVLLKGNKDTNFVSSLTFGMISRLAEYLIRTNRYIKKAI
                     EMTYSHVFLDEFQDTKSIQYDLVKACFFKTETIITAVGDGKQRIMLWAGARKSIFEDF
                     QNDFLSQKRTLIMNHRSAPRLVEIQKAMYNSLNEEAIDLKTNEKWNYEDGEVYLRLFE
                     DYIKEADILSEEIVELVETGIEINEICILVKQSVDIYSKEIINKLSERNIKARNEAMY
                     QEILKEDIIKTLVSLFRLSLSDRNPDDWDYIYDILGELYGIDEGYNPKILNDFITKVE
                     LMINDLKVNLNITDEKQFSDLVDSKVEYISYEKFASKFQKYKSKDYFDDLVDKFKKLV
                     WIEYNETKDWIKAIDNFEGKNSIPIMTIHKSKGLEYDTIFFVGLEDSAFWNFKNQPDE
                     DRCAFFVALSRAKRRIDFTFSLDRPAGFSNSQKHYCINEFYELFDNTEIVKKIEY"
     gene            52502..52696
                     /locus_tag="ACGI3L_000302"
     CDS             52502..52696
                     /locus_tag="ACGI3L_000302"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196040.1"
                     /translation="MKKKTKISKKIVSFIMVFITIVTTILTSSVSAYASELDMSEQTG
                     FNYLGISPITGKKLIITFIV"
     gene            52699..53316
                     /locus_tag="ACGI3L_000303"
     CDS             52699..53316
                     /locus_tag="ACGI3L_000303"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196041.1"
                     /translation="MDNKIVFCVEPGIKTSSGGGYISEELGDKFISTTLPNYHKRKAE
                     ILEKVNRHNILPSWNNEKVAVKSGETIELEDKNGIIREMQLESNNTGTDILLEENTLK
                     ITANKNSNSGVISYIKIPKNEVGISIVYRKHNYQSLSEFHMESSMSANLNINVIKLGI
                     VKVKKIDEGTGKELANAKLRFEYDGDSKEIITGSNEIASIEDIIG"
     gene            53308..53829
                     /locus_tag="ACGI3L_000304"
                     /pseudo
     CDS             53308..53829
                     /locus_tag="ACGI3L_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901831.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            53942..54103
                     /locus_tag="ACGI3L_000305"
     CDS             53942..54103
                     /locus_tag="ACGI3L_000305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196042.1"
                     /translation="MAIAIIGVYLGFKREFSKLIGFLVVALIAVGLVFNTAGVKDILL
                     ELFNKIIGV"
     gene            54343..54570
                     /locus_tag="ACGI3L_000306"
     CDS             54343..54570
                     /locus_tag="ACGI3L_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196043.1"
                     /translation="MDIVKVFANNVRKYRNKKGLSQEAFAEKAGLHRTYICAIERKKR
                     SIALDNVQKIADALEIETYLLFIEGEEKECL"
     gene            54567..57506
                     /locus_tag="ACGI3L_000307"
     CDS             54567..57506
                     /locus_tag="ACGI3L_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFG9196044.1"
                     /translation="MKKLPIEKLIENLGFSGSKNLVNIDMLTKLDISKHDVKTLKVIN
                     PYAIYLVNSKPFILFIESSFEEKKLQQISKLIWNAQIPIAFICDSNSVKIFNGKALDL
                     KSYLIEEIYNQSIEDFSEESEFSYLKISDPLFWDQYTKQYTKTHLNDYLLDNITSLTN
                     KLKKKYKVKFATKLVLRLIFIRYLIDRGVDIAYKNFNHDIKASQKELLKITKNKVELY
                     ELFKYLKEKFNGNLFELNDEINNTCLTDEVFILLSDFLSGKISIDNGQMSLFSMYDFN
                     IIPVELISNIYEILLGKEIRNKDNAFYTPNYLAEYILDKTTLEFLKNNRQYKILDPSC
                     GSGVFLVNSFRRIIDMNLGDKLFCEDDKLLKELLLSNIYGIDINEDAIDVTIFSLYLT
                     ILDYKDPKILSEFKLPNLKGCNLIASDFFDDNKLESLKKINFDFIIGNPPWGSVSDGL
                     HLDYCNKNGYNDMQQNKEISRSFIFRAKDFSSRNTVCSFVVHSKILYTQKKPSKKFRE
                     FLLKKSQIFSVVEMSSVRKLVFKNADAPAAVISFKYNESEENLNNRIIYTSLKPNVFF
                     KLFNIIVIEKYDVKYISQKLLLENDWAWKTIVYGFSKDIDIIMNIKKKYQTVNEIILK
                     NSFVHGTGIQINGNESHDATHLKGKWYVDSKKGIDSFYVDINKGKELTQDKMRRPKAN
                     QQEIFIPPYVLLKKGVDTKTYRYRAAFSNDAFVYSDAVTGICGKKDNLTTLYCLTGML
                     NSSFYSYLNIMLGTSIGIEREQGFSTEIFTYPAIESDEIANLVVKIQEATKLEKTTMF
                     LNEKNSCKYIKQLDKLILKSFNLNDDKFIDYAINIQIPELTNSKSTNIYRKITKEDLI
                     NYSECFKEQFSSIYRRVGKSISISVYPKILNRFTVFELEVTDEKTDREIMVKAEADNN
                     MELFTKIIRYDYNDVFHQIRDIIHFGENSFYIIKPNCYKYWHPAIAEMDLADVLDQIL
                     SDTGGEE"
     gene            57506..58180
                     /locus_tag="ACGI3L_000308"
     CDS             57506..58180
                     /locus_tag="ACGI3L_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196045.1"
                     /translation="MGGFKNSSLNFYLKQGLYEIIIDGLIDCCLLMSKSCIEQSRKIL
                     NHEEKIRTHLVENYLENDIERRKTSLSKQHLRFEVEAQENYDNKNESYEGRVDIKVIS
                     KDTLADRRAYYIIECKRIDGKETLNKKYITEGVQRFITEKYSSHYGKNIMLGFIVKDI
                     NIQSNIQKINSLNQNILYTYIDTDMLTVRSDSENNYAVCESKYKVKSKLLLLNHIFYN
                     FSSIIR"
     gene            58341..58757
                     /locus_tag="ACGI3L_000309"
                     /pseudo
     CDS             58341..58757
                     /locus_tag="ACGI3L_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003455547.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            58717..61164
                     /locus_tag="ACGI3L_000310"
                     /pseudo
     CDS             58717..61164
                     /locus_tag="ACGI3L_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            61304..61726
                     /locus_tag="ACGI3L_000311"
     CDS             61304..61726
                     /locus_tag="ACGI3L_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196046.1"
                     /translation="MRLEDIIDKESYEEKYDDLTVEIKKLSKEKKTLKASLINEKSIK
                     ARLREFRKILERNELLEKFDRYVFASIVDKVIVGVINEDGIVDPYKITFVYKTSFDDK
                     QDGHKFINKSPLETYSKDNNDNKKKCSYTNNETLRDCS"
     gene            62264..63298
                     /locus_tag="ACGI3L_000312"
     CDS             62264..63298
                     /locus_tag="ACGI3L_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HFG9196047.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            63385..63588
                     /locus_tag="ACGI3L_000313"
     CDS             63385..63588
                     /locus_tag="ACGI3L_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HFG9196048.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            63759..64919
                     /locus_tag="ACGI3L_000314"
     CDS             63759..64919
                     /locus_tag="ACGI3L_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HFG9196049.1"
                     /translation="MKLSKILLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            65177..65317
                     /locus_tag="ACGI3L_000315"
     CDS             65177..65317
                     /locus_tag="ACGI3L_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196050.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            66266..67666
                     /locus_tag="ACGI3L_000316"
     CDS             66266..67666
                     /locus_tag="ACGI3L_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HFG9196051.1"
                     /translation="MNQEIFFKIMNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMN
                     RHDILTNSFFDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGREITAINTTIPID
                     IKGEFVGALEISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAI
                     AKSKKACKSDASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGIL
                     FGTSKGGFTGAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTK
                     DIPIDVRIIATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFI
                     SKYNKKLNKKVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINL
                     NDYYNLKENKESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMN
                     RQNLQYKIKKYNIKIL"
     gene            67922..68989
                     /gene="ord"
                     /locus_tag="ACGI3L_000317"
     CDS             67922..68989
                     /gene="ord"
                     /locus_tag="ACGI3L_000317"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-diaminopentanoate dehydrogenase"
                     /protein_id="HFG9196052.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     NVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTIVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            69133..69441
                     /gene="ortA"
                     /locus_tag="ACGI3L_000318"
     CDS             69133..69441
                     /gene="ortA"
                     /locus_tag="ACGI3L_000318"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtA"
                     /protein_id="HFG9196053.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            69434..70864
                     /gene="ortB"
                     /locus_tag="ACGI3L_000319"
     CDS             69434..70864
                     /gene="ortB"
                     /locus_tag="ACGI3L_000319"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtB"
                     /protein_id="HFG9196054.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSYFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            70942..71316
                     /locus_tag="ACGI3L_000320"
     CDS             70942..71316
                     /locus_tag="ACGI3L_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HFG9196055.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            71310..73514
                     /gene="oraE"
                     /locus_tag="ACGI3L_000321"
     CDS             71310..73514
                     /gene="oraE"
                     /locus_tag="ACGI3L_000321"
                     /EC_number="5.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ornithine 4,5-aminomutase subunit OraE"
                     /protein_id="HFG9196056.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            73514..74923
                     /locus_tag="ACGI3L_000322"
     CDS             73514..74923
                     /locus_tag="ACGI3L_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlmL-related ornithine degradation protein"
                     /protein_id="HFG9196057.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            74908..75972
                     /gene="orr"
                     /locus_tag="ACGI3L_000323"
     CDS             74908..75972
                     /gene="orr"
                     /locus_tag="ACGI3L_000323"
                     /EC_number="5.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine racemase Orr"
                     /protein_id="HFG9196058.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            76002..77423
                     /gene="nhaC"
                     /locus_tag="ACGI3L_000324"
     CDS             76002..77423
                     /gene="nhaC"
                     /locus_tag="ACGI3L_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFG9196059.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            77852..78316
                     /locus_tag="ACGI3L_000325"
     CDS             77852..78316
                     /locus_tag="ACGI3L_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9196060.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            78550..78912
                     /locus_tag="ACGI3L_000326"
     CDS             78550..78912
                     /locus_tag="ACGI3L_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9196061.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            79507..80367
                     /locus_tag="ACGI3L_000327"
     CDS             79507..80367
                     /locus_tag="ACGI3L_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9196062.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            80625..82739
                     /locus_tag="ACGI3L_000328"
     CDS             80625..82739
                     /locus_tag="ACGI3L_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFG9196063.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REKYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            83280..84233
                     /gene="blaCDD"
                     /locus_tag="ACGI3L_000329"
     CDS             83280..84233
                     /gene="blaCDD"
                     /locus_tag="ACGI3L_000329"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HFG9196064.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            84577..85260
                     /locus_tag="ACGI3L_000330"
     CDS             84577..85260
                     /locus_tag="ACGI3L_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196065.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            85257..87917
                     /locus_tag="ACGI3L_000331"
     CDS             85257..87917
                     /locus_tag="ACGI3L_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9196066.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(88098..89279)
                     /locus_tag="ACGI3L_000332"
     CDS             complement(88098..89279)
                     /locus_tag="ACGI3L_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9196067.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(89279..89941)
                     /locus_tag="ACGI3L_000333"
     CDS             complement(89279..89941)
                     /locus_tag="ACGI3L_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196068.1"
                     /translation="MAKILLLEDNDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(90073..90711)
                     /locus_tag="ACGI3L_000334"
     CDS             complement(90073..90711)
                     /locus_tag="ACGI3L_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9196069.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            90890..91495
                     /locus_tag="ACGI3L_000335"
     CDS             90890..91495
                     /locus_tag="ACGI3L_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9196070.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            91999..92748
                     /locus_tag="ACGI3L_000336"
     CDS             91999..92748
                     /locus_tag="ACGI3L_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9196071.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            92745..93509
                     /locus_tag="ACGI3L_000337"
     CDS             92745..93509
                     /locus_tag="ACGI3L_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9196072.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            93608..94429
                     /locus_tag="ACGI3L_000338"
     CDS             93608..94429
                     /locus_tag="ACGI3L_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9196073.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            94443..96107
                     /locus_tag="ACGI3L_000339"
     CDS             94443..96107
                     /locus_tag="ACGI3L_000339"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFG9196074.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            96112..97986
                     /locus_tag="ACGI3L_000340"
     CDS             96112..97986
                     /locus_tag="ACGI3L_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFG9196075.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT        37843 a        11137 c        16824 g        32368 t
ORIGIN      
        1 aaaataactt atagagatta gaataatttt agtttatata ttttttaaaa ctatacagtt
       61 gttataaaaa gaaaaattgc atacaagtca aaaataagtg ttattttata aaaatacgac
      121 aaaaatttta tttactactt atacaaataa catgcaaata acatataaaa tttaataagt
      181 aaaaaaaatg aaagatataa attatcattt tagtatttta tttagtcgaa gtaaattatt
      241 caaatgaaat atatctcatt tagataaaaa attttagtaa aagtaaaaaa aataatatat
      301 ttgttaaaaa ataaattgac aaaatattca gaaaaaaact tcttgaccta agagagtaaa
      361 ataaataaaa tctaaggtat agagatgaaa tctataaaat tattttaagt ataagttaaa
      421 aatatagatg atgcatttaa gatttataaa aattagagat gcataattat tttagggagg
      481 tttttagtat ggagaaaaaa gaaaaggtag tagaaaaatc aaatgttgaa gtatgtagtc
      541 ctgaaattgt caacagtgtt gaaacattaa gaatgagatt agaagaaatt agattggcac
      601 aaaaagaatt tgcaacattt acgcaagaac aggtagataa gattttctta gctgcttcaa
      661 ctgcagctaa tcaacaaaga atacctctag caaaaatggc agtggaagag actggtatgg
      721 gtattgttga agataaggtt ataaaaaacc attttgcctc agaatatatc tataatgctt
      781 ataaagatac taaaacttgt ggtgtcatag aaaaagatga agcatttggt tttacaagaa
      841 ttgctgagcc agtaggtgtt ttatcagcag ttataccaac aactaatcct acatcaactg
      901 caatattcaa atccctaata gcactaaaaa ctagaaatgg tataattttc tctcctcatc
      961 caagagctaa aaactgtact atagaagcag ctagagttgt acatgatgca gcagttaagg
     1021 caggagcacc aaaaggactt ataggttggg tagatgttcc ttcgattgaa ttaactaatg
     1081 ttgtcatggc agaggcagac cttatattag ctactggtgg acctggaatg gttaaatctg
     1141 catactcttc aggtaaacca gctgtcggag ttgggcctgg aaatgtacct gcaataatag
     1201 atgagagtgc agatataaaa atggctgtaa gttcaatctt agtatcaaaa tcattcgata
     1261 atggtatgat atgtgcttcc gagcaagctg taatagtacc agaaaaaata tatgaagaag
     1321 ttaaaaaaga atttaaatat cgtggagcac atttcctaaa taaagaagaa actgaaaaag
     1381 taggaaaagt agtaataatt gatggttcat taaatgccag aatagttgga caaccagcac
     1441 atgtaatagc caaaatggcg gatgtagaag ttccaaaaac agctagaata ataattggtg
     1501 aagtagaatc tgttgaatta aatgaacctt ttgcacatga aaaactttct cctgtacttg
     1561 caatgtacaa gtctaaaagt tttgaagatg cagttgctaa agcagaaaaa ttagttgcag
     1621 atggaggcta tggtcataca tcttcattat atgcagactc tataaatcat ccagagagag
     1681 tagaaaagtt tgtaaatgct atgaagactt gtagagtatt agttaatact ccatcatcac
     1741 aaggtggtat aggtgattta tataacttta aattggcacc gtctcttact cttggttgtg
     1801 gttcttgggg tggaaactca gtatctgaaa acgttggagt aaaacatttg cttaatatca
     1861 agacagtagc tgaaaggaga gagaatatgc tttggttcag agcaccagaa aaggtttatt
     1921 tcaaaaaagg atgtttaggt gtagcagcaa gagaatttaa ggatgttatg gataaaaaga
     1981 aagcatttat agtaacagat tctttcctat ataataatgg atatactaag aaattaactg
     2041 atttattaga tgagatggga attaagcata ctacattctt tgatgtagct ccagacccaa
     2101 cattagcttg tgcaagagaa ggagctaaag ctatggctga tttccaacca gatttaataa
     2161 tagctgtagg tggaggaagt gcaatggatg ctggtaagat aatgtgggta atgtatgagc
     2221 atccagaagt agatttccaa gacttagcta tgagatttat ggatataaga aaaagagtat
     2281 atgtatttcc taagatgggt gaaaaagcgt attttgctgc tatcccaact tcagcaggaa
     2341 ctggttcaga agtaactcca tttgcagtta taactgacca agattcaggt gtaaagtacc
     2401 cattagcaga ttatgaatta atgccaaaca tggctataat tgatgctgat atgatgatgg
     2461 agatgccacc aagattaaca gcagcatcag gtgttgatgc tttaacacat gcattagaag
     2521 catatgtatc tatgttaaga actgaaccag ctgacggtct agcactacaa gcaggtaaaa
     2581 taatatttga atatttacct cgtgcatata aaaatggaaa gaatgataaa gaagcaagag
     2641 aaaaaatggc aatggcatct actatggcag gaatgtcttt tgcaaatgcc ttcttaggaa
     2701 tatgtcactc tttagcacat aaattaggtg cattccacca tgttcaacac ggtgttgcaa
     2761 atgcattatt aataaatgaa gtaatcaagt tcaattgtgc agaagctcca aataagatgg
     2821 gtgcattctc acaatacaga tatcctgatt gcatacaaag atatgctgaa tttgcttctt
     2881 ttgcaggtat taaaggaagt acagaccaag aaaaagtaga taatcttata aaagcaatag
     2941 atgaactaaa ggcaaaagta ggtcttccta agactataaa agaggctgga gtagaagaat
     3001 ctaaattctt agaaagattg gatgctatgg ttgaacaagc ttttgatgac caatgtacag
     3061 gtgctaatcc tagataccca ttgatgagtg aattaaaaga gatatatcta aaagtttatt
     3121 atggtaaata atatctattg tgcaacatag gttctattgg gtttgtatat aaattattag
     3181 atttgaatat aaatagagtt ttattagaga cacgtagaag taactataaa taatagatta
     3241 taatttaaat tctaaatgga aatgataaaa agtcagtaat ttaatggtaa tttcgaatat
     3301 gtgtatttaa tcaattaact ttaaaattag tcggaaaatt tttttattac atataatttt
     3361 aaagcataat atataaaaaa ctttatgaaa aaattataaa aatattcaga aaattctatt
     3421 gactaattta tttatcatga tataataagt ttagaaaaga aaaaaattgg ggcctattaa
     3481 ggccccctta ctattttttg atagatttat ttaaaattac tttctcattt tgatttttta
     3541 tatttattat agagtcagta taatccactt caaagttggc aaaagcagag aataaatcta
     3601 tatctcttaa caaatgaatt gtcatacatt gattgttctt atttagcctt agaatcaatg
     3661 ctcttacaaa tggaaattgt attctagaat taaataagtt agaaccatca gtatctatat
     3721 ctaagctacg ataattaata tctataaata tatctacatc ttcattttct tctcttatta
     3781 ttctgtagtc aaaatccaag tttaaattta aattacctaa aatcaataac atttaaatcc
     3841 tcttttctat aaatagtttt agagtgttaa tttaagctct ccatctatta tagatataat
     3901 tctatctgct tttctagcaa tattttcatt atgtgttatt attataagtg tttggttata
     3961 tttttttata gaacttttta gtaaatccat gacttcttct gtagttttac tgtccaaatt
     4021 tcctgttggt tcatctgcta ggattatact tggttttgca gataaagcac gtgcaatagc
     4081 aactctttgc tgttgaccac cagataattg gttgggaaga tgatttttcc tttcattaag
     4141 acccaataaa tttataaggt catcaatata ttctttatct atttttttat tgtctaactt
     4201 tagtggtaat tctatatttt cctttacatt taatacagga attaagttat actgttgaaa
     4261 gacaaatcct accttttgtc ttctatatct tgctaattct ttatctgaaa gacaacatat
     4321 atctttacca tctaccttta tagtaccatt acttggtctt tcaagaccac ctactaaatg
     4381 tagaaatgta cttttcccac ttccacttgg tccaattata gcaacaaatt cgcctttatt
     4441 tatttttaaa tttgcattct ttagtgcatg tacagatgtt tccttttttc cataaatctt
     4501 acctaagtta atagtttcca atataggcat aattattcct cctattctgt aatgtttata
     4561 gcttcaacta tactaatttt atttatcttt cttgatggaa tatatgtagc tagaatacct
     4621 acaattatat ttgctacaac aactagtata tatattttgt aatctattga aaatcccaat
     4681 ccatatgata caaagccctg catataatac attttaaatt gtattataat tcctgacacg
     4741 atagtaatta tacttgagag tacaccatat aatattcctt cataaagtat catattttta
     4801 aagcctctct cagagatacc aatagctctt aacattccaa attcactagt tcttgaagtt
     4861 aagttataac ttatgttgtt tattatgtta agtacactga ttatgaacat tattgctact
     4921 ataccataac tataaatcat agttctagat gtcatcttat cagaattttc tttttctacc
     4981 atcatatcta ctgttgtagt tccaggaact tcacttccaa ttttacctaa aaggttattt
     5041 atttttttct tgtttgcatt ttcattaagg tctgcataaa ctaagttata cttatctaca
     5101 ccagttaatt tttttaggta ttcgctactc gttattacat ctacaccatc atctccagag
     5161 tacataccat tatctgcaaa aggataactt ataatagctc caactttaaa ttcatattct
     5221 aagtattcat aattatcttt tagactttca taaagacctg tatccatccc accctttgga
     5281 tatttgactt ttatagtatc acctactttt atatctacag ctggtgttcc ttcaccagga
     5341 gtaaaagtct ttgtgtattt ctgtgtttta gaaatttctg gtacatatac aatagctaaa
     5401 ttttcttttt tcattttttt caagtttata tttccactta ctaagtattt ttctaatgac
     5461 tttatcatct catcattata accttttagc ttttgcttta gtgtatattt gccagtagtc
     5521 ttatttttta tgaacagagg atttagctta taataaggag ttgaatttat agcttcgtag
     5581 taatctaatc tatttatttt atttacctct attcttgtgt ttaagatact agcagttttg
     5641 actttgtcaa ttccatctat attttttatt ttatctatct gattatcatt aaaccctttt
     5701 atatctttaa aagaagtatt gttaccaatt tcattgagat aaacatttga tagaataaaa
     5761 tctgcattca tatatgtttg ttcttgagta gatttgtttt gcacatctaa aaaagaatat
     5821 ttataattgt cttttatgac gattatacct cctatactca tagataatac aattataatg
     5881 aacccctttt tatttctaaa gatgtttttc gcagatatag attttgttac tgacatattt
     5941 aaagttaatt ttgatattaa ataattaact ttggttacat ttttatcagc tccaaaagtt
     6001 tttctgatag catcaatagg agaaattctt cttattttta agtatgtaaa gaaacttata
     6061 attagtatta ttagtattgt acatgcaatt gataagagaa ttattttatc tggaataaca
     6121 aaaggtgtaa catttatatt tccttcaaat tgaatatttc ctacagacct attaaatatt
     6181 tgtgcacctc ccatacctat acatatacct ataggcattg ctattagagc aagtatgaaa
     6241 agttcataaa gcataagttt gaaaatccta aagttggtgg aaccaatagc tcttaagacg
     6301 ccatattcct gtactctttg gtatattgat ataacataga tactatatat tacaatacca
     6361 gcaaatagac tcatagcaat tgcaacgtat ttacttgaat tatctaaagt accgtttttc
     6421 atagtagatt ctataagcat tgagtttctt cctatacttt tctcatctaa catagcattt
     6481 tttattatat tgtctatgtt tgtatttata tcactgcctt cattaaattc aatataagtt
     6541 gtaaaatcat tcagttctga ttcattgaga ttagaaaaaa tttcacattg tccctttttt
     6601 ttctctataa atctatcttc aaggattcca acaactttaa aagtttctgg attttctttt
     6661 tgatataatt taaaagtaag gttttgattt atctctggtt ttaagcccat actatttaaa
     6721 atccatttct cgactaccac ctcattgcta gcttttggaa atcgaccttt tataagttta
     6781 gaatgactag tcaaataatt tttatttgta tatagtatgt ttataggtaa tttttcatta
     6841 acatctgtag acgcatagta agatgttata cccagatttt taatatcttt gctagatttt
     6901 atggacttta attgattttt ctttatattt ttaaagtata catggtcagt tccaagctct
     6961 cttttcaatc tatctacatc tgcttgctga gcacttcttg agagagtacc aataccaaca
     7021 acgagtgatg tagcaagaat tatactcaca acaattgcta aagacctagc tttataactt
     7081 tttatatacc ttagtactat tttcaaatta tctttcatat ttaccacttc ctttcttaac
     7141 taaatcaatt atatatttat ctaaaatata tagcaaagta agtattttca aattttaagt
     7201 agttaattgt acaaattcat ctgtattttt acaagtttaa ttaatatata tgtaaatttt
     7261 aactttttac ataatttttt taaaatgata taatccctat ataaattgta gaggggaggg
     7321 gaatcatgga taacaatttt gtatttccta tagtaatact aactttgttt atatttagca
     7381 atcttataat gaataagtat aaattttaca aagaattaga catattaaaa agaggcatat
     7441 taacattttt tatatcgtgt tttgcattga ttttatttat ggagggcact aaatatatac
     7501 aattaaggtt aggatatagt tttttacttg aaggagtatt aaatattata ctttttttgg
     7561 ttttaattat tttaagtttt tatacaggct ttaaagttat aagattgata aataataata
     7621 atgaacagga atataaatta caaaaactag atagtaaaat aaatcataag gataatataa
     7681 ttatcaaatt aagaagtcaa aaacatgact atttgaaaca tttgcaagta gtgtattctc
     7741 tattaaatac tgggctagat gaagatgcca aagaatatat aatgaatata tcaaatagct
     7801 ttaaatcaaa aaattcaagg tatggaaaag tatcttattt agatgctata gcttcattaa
     7861 aatacgagga atgtcttgaa aaggatatat cttttgatgt ctacattcaa gattttatgg
     7921 ataatttaga gattgaacct aatgatatga gttcagtact attaaacata atagataatg
     7981 caatagagtc tttgtctact ataaaaaaag aaaagaagta tataagatta catgcatatg
     8041 aagatgaatt tcagtatatt atagctataa aaaataatgg tcctaaaata cataatgttg
     8101 aaagtatatt ttggaatgga tttagtacta aagaaggaca agatagggga tatgggctac
     8161 atttagttaa aaatatatta gataagtatg attatagtat acttgtaaat agtgatgatt
     8221 ttttaactga atttgtaatc ttaatcccaa aatattatta gttaggagga gaaaagtcta
     8281 tgataaaagt tttgatttgt gatgatgata agattgtaag agatgatata gcaaatatag
     8341 ctaaagagtc tggatatgta gattatgtta aaaaagttaa ggatggtata gaggcaattg
     8401 aatttataaa aaatgagaaa atagatttat tgattattga cattgatatg ccatataaaa
     8461 atgggattga ttctgctgaa gaaattcttt ctatagataa ggatatacat atagtatttg
     8521 tgacgggttt cgctgattat agtcttgaaa gctttaaagt gcatcctata gattttgtag
     8581 ttaaaccatt taaaaaagaa aaaatacttg attcaattaa catagcaata gaccatatta
     8641 actcccataa gattgctaat aataatttta tagaagacac cctttttgta tataaaataa
     8701 ggaagcagat acatatgatt aattttgatg atatagttat gtttgagaaa aattcaagag
     8761 caattaatct acacactaaa gatgaagata taataaagtt ttatgagaac tttgatgatt
     8821 taaaaaaacg cctacctcct aatttcttta tgacccatag acaatacata gtaaatctaa
     8881 gatttataca taaggttata cctataaata aatcttcatt agagataagg tttataaatt
     8941 ttcaagaaaa tgccatatta aacaaatctc tagaaaaaga ttttttatat agattttata
     9001 gggttaaaag attctagtga agatagaaga aaaatacttt ttgtgtgata taataagtac
     9061 cgtaaagata atgtataaga gaagtttata taaaaattat ttgtaattat gatttaatct
     9121 atataaatta cagtatagta tatattggac tttctaattt ttttaagaaa gtccaatata
     9181 ttttagagat agtttttata cttataaatt acttaagata ctagggtctt taatcttact
     9241 atcttcagca agtaatagta tcttagacat aatctcagca gttttagggt cttcatcagc
     9301 gaatggaagg aatatcttac ctctactttg agaatgtata ggaagtatat tcaaagcacc
     9361 catccctttt ttatgtacaa taccagaacc catatgcaca gaatactcac ctaaattacc
     9421 tgctataaga gcatgagagc cttcaaaatt gacattgtta atttttaata ataataaaag
     9481 ttctttagca attgctatac gcatctctac agtagaatgg ctagtttcag ggtcaacacc
     9541 accagcatga gcgacactta caacaaggtc tatatcacgc ataacttctg agaatagaat
     9601 tggaggtata gaagctaatt ctaaactttt ataagttttt ctatcaaaaa attctactgt
     9661 ttcaatagta ggaggctcta tatctgctgg tgaaaaccaa tctgcaagtg caaacatctt
     9721 tgccactata ttttctttat aaaatacttt ctgtaatccc tcttcataat cgacagtcca
     9781 aagctgattt ctaagaagtg ctacagtttt ctttggctga atttggtgac cagcatatct
     9841 gcgagatata gttttttcag ataattcatc actgtttatt ctataatact cacggaatac
     9901 ttgcttaaat ggttgaacaa tttgcttact aaataaatca tgttggaact cactccactt
     9961 accagattca aacaaatgaa ctggatgtgc aagttttaat ttattttttg ccgtcaactt
    10021 ataagtttca ccttctatat tgcaaataaa gaacttagac ttatcattat aaacatatcc
    10081 aatattatca tcacataccc atactagatt tttaatcaaa gggcagataa ctggattttt
    10141 atagatattg gcaatttctt taactgtaaa tactatttca tttttcatag cttgttctaa
    10201 actctgtttt gcacgagaat actgactctt taaatctttt tggacagatt taagttcaag
    10261 tacatatgga tgtttagcaa tagcttttgg tatactcttt aaagacttgt tgcctttttg
    10321 aactttagta gatgcttttc cgttttcatc aacatctatc caaattgaag taccatcaat
    10381 atcttttggt ttaaatagat gagcaacttc atttagtttt tcagtctcaa gagcccacat
    10441 catacgattt acatctccaa atccagcact tctagctaga ttttctagcg ctatagtaca
    10501 agcttttgat tcactttcac gacgttgtgc accaaattgc ttgctttctt tagcaaactt
    10561 ttgaataaat tcataacgga aagttgcttc ttttaggtct ccttttttca taggaagtaa
    10621 agagaaactt ctcaatttat cttgatttct atttgtttca atttctttca tcaacatgtc
    10681 tttatcaagc ttaccaagtg tagcatcagc atagagttgt gcacgtctat gagagttacc
    10741 accactagtt atatatttag ctgacttgta aagtatattg aatctttctt ccccaatagt
    10801 tttatatgaa tctaaaaacc aatctacatc aaatgcacca tcaatgaaac tacgtggtga
    10861 aataggggag aatagagcaa cctctgattc tttttgtgca gagaagcctt catttatatg
    10921 tgcatggaag taccaaattg tacttttcag acccttccag tttaaatatt tttcaattat
    10981 gtttacccat tgaggggcat acatagcaga ttctatcaat cttaactcag taatgtcggt
    11041 atttttaagt aaacttttta atttttttga atcatcttct ttagtaggat agcaattttt
    11101 aagtagagaa cttaaaacat ctttttttga ataattgcta ccatatgaat atcctctctg
    11161 gaaagtttct ttaccaagag cgaccaaaat atttacaaaa taatttatac cttcaaagta
    11221 ttgtatatta ttagctagat tagacacttc tgttggcata tcacctctac gtgattcaat
    11281 ttctataatt cggtttgtaa cagtttttaa attatcttta agccaagggt acttttctaa
    11341 tgtgtcgcca gcccatctag gatttgtcaa tgttcttatt atatttgatg cgttgtatcc
    11401 acttatcatt tctctattaa cttgctcttc agtcattaat cctaattcat gtgcacgagc
    11461 aaacacattt atgctagtat agaaaggaaa cttatattct agcaactgat aatttgaaaa
    11521 cgtagtgtag aaaaacttag taaaagaaat atcatcataa ataaacgaat gtgctttatc
    11581 aagccaatag tttaaaatag gggcatttaa agcagggcag tattcatttt gtctgtaata
    11641 gtttttagta aattcaactc tttgtttttt acattgttct atagtcaata agtttctaag
    11701 tttatagtat atttctaaac aatagttaaa tatttcttta tggtcaaact catttagtaa
    11761 aactcttaaa agttttcttg taagtccatt aaatttaagt ttttcaagtt ttgtatatat
    11821 tttattttgt tttttagagt caaggacatt tgaatatata gatgaaaacc aacttttttc
    11881 tgtttcatta tatccacatg tacttatact ataaaataag atatcaagta ttaatttgta
    11941 atctaagtca agttttttac tagtttctct ccaaagctct gctaatggat aattatcaag
    12001 agtatcatta gaaactttat atttaatagg agtcaagtta taagtagaat aacctaaaag
    12061 tactttgtct acattacctg accatctttc aacttcatat tcataatctg cattttcagt
    12121 aataagttca tcaaattttt cataaacttt tattatttta tttatatccg tatcgagaat
    12181 tttttttgct tctttttttg ttgctacaga aacagaatcc tcacgagtag ataaacttat
    12241 atttgagata attttattaa gctttgatga gctattagaa tcatctttaa aatcaaattg
    12301 ttctggaatt tgaactttgt tttcagggtt atatattcca aaaccatttt ctttgcagta
    12361 atcatttttt gctttaccta acaaattatc aattagtatt tgaacttgag atgtattctt
    12421 tttagattta tcaatatcct ctataagtaa aataagctta ttatatagtt cttgtctagc
    12481 agtattgtct tttaataagt ttacaatttc aagacctcca aggcattttt gagaatttga
    12541 agattttatc agtgaagaag caatattttc caaatttgaa tcatcttgtt caagtaaaat
    12601 ttttattact gtttgtctaa tagagcttgt ctttaaagac aatagattgg ttatcttatc
    12661 taattctaca tctgttagct caagctttct aagtagactc aataccgttt ctctattgga
    12721 aacactctta tcacttaaac attccaataa aaattcacgt tgtctatctg tctttggttc
    12781 atttacaaaa ttgactataa gtgaagctct taaatctgaa ctcataagat gacaattttc
    12841 cataagcaca tctataaatt gagcattcat atcgtatgct gttaaagtca tcatacattt
    12901 aagtatttca tgagaagaaa tttcaatcca agtccatgga aatacacttc ctgaaaatga
    12961 ttttgtcttt gaatttaaaa tttctaaagt atgttttaaa ctttcaaatt gttcttttct
    13021 agcatcaaag tctttgtcaa taggagtgtt tgacaagtca aaattagttt ctctgttttg
    13081 ccaactatag tagtagccaa cagaaccttc tacatagaaa tttgtaatta cccatgctag
    13141 tatctctaaa tcatcaccct taatgttttt agatgctata gaatgtttaa aatatgtact
    13201 ttctgtatgc gataaaaagt aaagagctac aagtttttta tatttttcct gacaagaaag
    13261 taagttttca ataagagagt aagagtcata tatgttgtaa gttgcagtag cccataaggc
    13321 aaaataaatt tcaagattat cattgctatt aattgattct atacggaact tttcatcagt
    13381 caatgattta tatgaaagtt ctaaacattt acgtattatt ccaggttttt ggtctgaaaa
    13441 accaagtcct gtccatgtat ccaaggctct tataacagaa ctaaatcgct ctaaattgtt
    13501 gtccaaaata gtttttaaca tgtatattga tgcagaaatt gtaccctcat ctaaactctc
    13561 tacaatttgc tgtctaagtc cttcttgttg tttggctgcc aaaagaagtt tagaaagcat
    13621 ttcatagcat ttatcactat gactcttcat gataccaatt atcatttgtc ttgtaagtag
    13681 agcagtttga ttttctccaa atattacttc ttctaaagca cttattactt tttgatttcc
    13741 tttgtctatt tctagtgcta ttttatcact cattatagag tcatagtaca agaccttatt
    13801 tggaagagta agataatcta taactgaaaa atcataataa attaaatcaa catagtttga
    13861 aataaacctt ataatacctc taaaataatc cacaagttta tttgagcgat accctttacg
    13921 ataatatcct cctgaatatg tataatccat ctttctttta attaattggc aaagttcttc
    13981 tacttgttca gaagtaaata ttaattctaa tgcatttttt aaaggtccag aaaggagctc
    14041 gtccatattt ttaatttcgt agtagtggca attgtagtat ttctttatca tatttaagaa
    14101 tttgtcttca ggttctctat aatagtatga actattttct atgcagtccc aaagagactt
    14161 tgctaagtcg tagtactgtt ttgaagaaga tttagtaaaa ttatttttaa aattttcaat
    14221 tattttagga tttttttcta ctctagtacg ttctaacatt tatgtacctc caaattattt
    14281 attttaaaac attcttccag caagcaaggt aagtcttata aaagtaaata tatctccact
    14341 tttcagattt atagaggaat cgagtttttc aataacatcc tcatttataa gcactttgta
    14401 gattccatct tcaaatgcct gtaacgctac ctctattgcc ttttctacag attgtttatt
    14461 ctcattgtaa atagagccaa atccaacttt tccaatatca gcttgagatt caatttcttc
    14521 attagttaag aagtttatta ttgatttttc tgggattttc tcattatatt caagaacatt
    14581 tttagataca atttcagaga tagcttcttt taggcaattg atgttgtcag atacatcaaa
    14641 aggggtaagt tctagcatag gtttgcgttt gccaacagcc ttaactctaa aataaatttg
    14701 cataaaatca cctcgcaaaa tattaattat gtatttagaa atttaaaaat ttatctattt
    14761 gttatattat atcattttgt gaattattaa tgtgaattat ggaattattt tacaaaaaat
    14821 agaaaaaaag ctatcttaaa gtctaaaaaa gcaataaaag ataactttta actataatta
    14881 tatagaatta taactgtaca tttattaaat tttaatttta gaattatttt tgataactat
    14941 ctttttttat ttataaattt tgctcctaaa tattttttga tatcttcttc aggagaaaag
    15001 tcatcaataa gtatttcttt cccagtgtct tcaaatacta caagaacttc acagtcacct
    15061 tgtaagaaaa attttctaac tgtatcttct ttaacttctc taacttttat tacattcttt
    15121 ttttcttttt caaagtcttt tgtgtaataa cttcccatca tattaattat ttttgtatat
    15181 ctattcataa aatacctcca tatgcgatta aatttaaaaa atatgttata ataattgttt
    15241 gtattaactt aataattata acaaggagta ataataatga ctagtataaa aaataaagat
    15301 attttaaatt gtatagatta ttccattaaa aataagctct ttgacaaact aaatgatgta
    15361 tataagtcct tgccagtagg aaattgttct ggatgtggaa attgttgtat ggagtcagta
    15421 ggtataaatt taattgagtt cttgaatata ttttgttatc ttgaagatag agttgattta
    15481 aaaaaaagct gtataagtaa aatattagat tattattttg aggagtatac aagaaagaac
    15541 ccatgtccat ttaaagatac taataataga tgtttaatat atgaagttag accattaaat
    15601 tgtaggatgt ttggacattg gaaaaaagag gattataata aaaatttaga taatgttatt
    15661 gagaaaaata ataactatag agagttaatg aaaaagcaat atggatttga aataaatgat
    15721 gaagtagtaa attacaggat agattattgt gatagattta ttccaaataa agattattta
    15781 agtaaatcta agagattaag cttttttgat gagcttatga tattagactc aaatatttat
    15841 tcaagtggaa atatagatat agactttagg gatagaggta tagttgaata ttttatagag
    15901 tcattacttt atagaaattt agcatataat gtgaaaataa ggatatctaa agaatacaaa
    15961 ataagaaaaa gaactataga tagaataaaa aggattgttc ttgtatagtt ttatattagt
    16021 aagtaataaa ttgtatcata aatattgtca aaatgaggtg aagaaggtga atcttacaaa
    16081 agtaaaagga aatacctttt ttataaaagg tggcacgaat acaggaatat atgtatttga
    16141 agataacaca gcacttatga tagacccagg gttatgtggt tcaagaccta ggagagtaaa
    16201 taaagtatta gatgaaaata atatacaggt tagatatatt ataaatactc atggtcatga
    16261 tgaccactat ggagcttgta atcaatttaa agaatattat aaagatgtgt gtataatgtc
    16321 atctgaatac gataaattat atatagaaaa tccagaattg ttttcaaagt atattgttgg
    16381 gggaaagagc aatgtattta tggataatat cttaaaaaat aaaatgttgg atgatataaa
    16441 aatagataaa tctatagaag ctggaaaaat tgaattaaac aatgaaatgt ttgatataat
    16501 tgaatttcag ggtcatacac ctggtagtat agctgttttg acgaaggata atgtgatttt
    16561 tgttggcgat ttattgatag gagatgaaat tctatcaaaa tacgatttct tgtttctata
    16621 tgatatacaa gaacaaataa attcattaga aaaattaaaa aatatagatt ttgagtactt
    16681 agttttaggg catggcaagc aagttatatc gaaagaagat tcttataaat taatagaaaa
    16741 acatttgaat gctttaaaaa aatatttata tcaaataaga gagttgcttg tagaaccgaa
    16801 atctttagaa attttattaa aaaacattat aaataacaat aatttaagca ataattataa
    16861 agagtatcat ttttttaaat cttcgttagt atctgtcata agttacttag ttgatttaga
    16921 agaaataggg tatatattgg aaaatggaga attgctttac tatacaaaaa caaaataaat
    16981 tatgataaaa taaagaaggt cataaaaaac aaataaaggg tgagcaatat ggaatacgaa
    17041 aaatggaatg agatactagc accttatgaa catgcagtag aggaattgaa aataaaattt
    17101 aaaaatataa gaaaagaata tttagcaaaa ggtgaatatt ctcccataga gtttgtcaca
    17161 ggtagaacaa aaaaaatatc ttccataata tctaagttaa aaaggataaa tgcaaaagat
    17221 atagaaactg aaattgatga tattgctggt ataagaataa tgtgccagtt tgttgaggat
    17281 atatatgcta tagttgattt gataaaagta agaaatgata tgactataat aggagaaaaa
    17341 gattatatta caaattacaa agatagtggt tatagaagct atcatgttat aataaaatac
    17401 cctataaact ccattgcggg ttcaaaggaa attatatgtg aaatacaaat aagaactctt
    17461 gcaatgaatt tctgggctac aatagaacat tcattaaaat ataaatatga ccattacata
    17521 cctgagactc ttgctgaaag gcttagaaga gcatctgatg ctgcctttct tttagaccaa
    17581 gaaatgagtg aaataagaga ggacataatg aaagctcagg ctatgtacca aatgaagtct
    17641 atagctatta gagatacttt aaatagaata caagagttat atgacttggg tgatacacat
    17701 aaagctatgc agtaccaaag aaaacttgat agaactgaaa cagataaaaa tataactgaa
    17761 attttggaat taaaacaaga aatagatata ttattagagc aatataagga tactaaggta
    17821 gatgataaag tagttcagta aaaactactt gtagaaaatt tgctaaatat taatggggct
    17881 gcctcttaat ggaaaataat ttctaaaaag agacagccta tttagtgtaa ttaagaaagg
    17941 aatgatatta tgagtttgta tgctataggt gatttacatt tttcaacatc agtcaataag
    18001 ccaatgaata tctttggaag taattgggat ggtcatgaaa agaaaattat agataattgg
    18061 aaagaagttg ttaaggaaga agatatggtc ttagtactag gagatacatc ttggggaatt
    18121 aatttatccg aagctaaaaa agatttagat ataataagca aacttccagg tcagaaaata
    18181 cttataaagg gaaatcatga ttactggtgg acaaccgtta caagtttaaa taagctatat
    18241 gaagacatgc gttttattca gacaaatttt tatgaatata aagattatgc aatttgtgga
    18301 ggtaggggct ggatatgtcc taatgatgtt aaatttgatg agactgatga aaaagtttat
    18361 aaaagagaag aacatagact tagactatca ttagaatctg ctcgtaaaag tggtcactca
    18421 aaaataattg tgattactca ttatcctcct acgaatgata aattggaaga atctttattt
    18481 acaaagttat ttgaagaata taatgttgaa aaggtgattt atggtcactt gcatggtaaa
    18541 gaatctttta aaatgggatt gaaggggatt cgaaatggag tagaatatac attagcatct
    18601 tgtgactata cagaatttaa tttaataaaa gttcacgatt aaaaaacata aattggtaaa
    18661 tactataaga tacatgatta aaaataaata tttgagggat ttcggttttg agaaaggaga
    18721 cacgacttat gaggtggata ttagttttta tatttttata tcttattcct ttagtagtga
    18781 tattcagaaa ttacaagaat tttaagaggt cttgtatcta cagtagtatt tatgtggtat
    18841 tagctacaac aataatgata agtaatattt atatgagtgg acttaataaa ataaaagagt
    18901 ctatgtatta tcacaattat atttctgatg agacatatga tgaaaagtat gtatcaaatt
    18961 ttaaggaaaa agaaagtact gatttaaaac aggataataa aaagaatgaa gaaatatcaa
    19021 ataataaaaa tttaaacaac aaacaagata gaaatataca aaataaagaa agtaatgaag
    19081 aaggaagtaa tgatataaaa gaaaagaata attctgatag taatgtttca gtgaataata
    19141 aatcagaaaa acaagaagat aatacaaaag aaaataataa atatacaagt aaagaaaaaa
    19201 atagtgaaga tataaaaaaa atagatatgg aaagtatagg aatttttaag aaagaaattt
    19261 ataatataga aagagcagct ttagttccaa tgagagaatg tataccttac actaaggata
    19321 tagcaaaaaa tataactaaa ttatctagta taaaaaaaga tgttacaaat gccagaaaca
    19381 agtgtaaaga agttgtaaaa gaatatgaaa atatgcagat tccagaactt tctaaggaga
    19441 agtatacaga aacattgagt aatgctagag atgacgtaaa gaaagcatat gagcttagag
    19501 aaaaatctat ggaaagtgct ttgaaattaa taaatactaa aagccctaaa tatataggga
    19561 agataacaga atatcttgat ttatcagata agcagataga aagttttaaa aatagattga
    19621 acgatttaaa agaagaaata aataattcag aaacaaataa tattaattaa taagatttaa
    19681 agatataagt taaaagggag attatgatga ataaacagag tataggaaaa ctaaatatgt
    19741 tttttatggg gattactcaa agaaaccttg ataataggga tttttttatt gagttagagg
    19801 tgatttttaa atctggaaga aaagagttta aaggaattgc aatagaggaa gataataaat
    19861 ataaatttaa ttttaaagga aaatcagatt tatatacgtt taatgagttg cttaagaata
    19921 tttctaaaga ggcagaaaat tatgatggat tagtatttaa atatgttgag cgaggaacta
    19981 ttgttgtaat tgaaggagac aataagaagg taaatgtaaa atatttagat aataaggaag
    20041 aagtacctaa aatagatgaa tttacggcat ctcaaataaa aaacagagat tattatgtaa
    20101 aagtaggaca agcaaatgca cttttaaaag aaattggagt acttacaaaa gatggtaaga
    20161 taaaaaatga taaaataaga aaatacaatc agatagacca ttttgttgaa ttgatagata
    20221 gtattttaaa agaaataaag gataaagact gtataactat cttggattgt gcttgtggaa
    20281 aatcttactt aagctttgtc ttaaattttt atataaaaga agtattgaag aaaaactgtt
    20341 attttatagg aatagattat tcagatgtag ttatagaagc atcaaaaaat atggctaaaa
    20401 acttgggtta taaaaatatg tcatttataa aagaggattt gactaattat acacctaata
    20461 gggatgttga ccttgtaata agtctacatg cttgtgatac agctacagat atggcaatag
    20521 gtctaggaat tagagcaaaa tctgaagcta tagtagtagt accatgttgt cataaggagt
    20581 tattagggca atatagatat gaagctatgg aaccaatatt aaaacatggt gtatttaaag
    20641 ctagatttgc agatttaata actgatggtt taagaacatt gttattggag ggcaatggat
    20701 atgatacttc tgtagtagaa tacatatctc cacttgatac accaaaaaat ttaatgataa
    20761 gagcgataaa aactaaaacg aataatgaca aagcattaaa agaatataaa gaactgaaat
    20821 cacaatttgg agtggaacca accttagaaa aacttatata ttagttaaaa atgtaaaatt
    20881 tacgaaaagc ttgcttaaat atgcaagctt tttggtatta tataggtata gtcatatcca
    20941 gagttttgat ttataattaa agctgtgcta taatatttga ttaatcaaat caataaatgt
    21001 tacatggagg taaaaatgaa caaattgaat atatgtattg atatagatgg aacaataaca
    21061 agcccttatc attttcttcc atacctaaat gatatcttta ataaaaatat aactgaagca
    21121 gagtgtataa cacataattg ggaagaattg tatggttcgg gaataagaga tgtgtatgcg
    21181 gagtttaata ataagtatat acactcatat gatgaagcaa agattgtaga gggtgctaca
    21241 gaggtaatta gcacattatc taaaggacat aatttatctt ttgtaacggc tagacatgag
    21301 tgtttaactg atgtaactaa aaattggcta tcgagacaag gattttcaga tatagatgtt
    21361 tacttattag gaagtgatta taaagttgaa aaggcaagag aactgagttg tgacatattt
    21421 atagaagata atcctttaaa ctcagtgcaa ctagctgatg atggtgttaa agtaatactt
    21481 ctggatacta actataataa agatgttaaa catcaaaata tagttagagt tagtaattgg
    21541 atagatattg aaaagattat aaaacaaggt atttaaagat ttgtagattg aaagggggag
    21601 catatgatag atttaaaaat tgaaaataga aaaggaaaaa tccatgtaaa gagcagtgaa
    21661 ataaaagaca ttttagaatt acgtccagac ttcgaatatg tacaagatat atcaaatact
    21721 ataaatcaag aaaatatatt ggtatttgat tgccagttga caggaaattc ttttgatatg
    21781 gatgatttag atatagaaga aatattggaa gagttaggtg aagaaataga tgagtcttat
    21841 ttcagtgttt tatttgaaga tgtaagagcg tatttaaaag atgctactga tgagatagaa
    21901 gcagacttac aggataatta cttatttgat aatttgagat gttattttga tatatacaat
    21961 ataaatcaag aatttacaga ttttaagttt gtatttttag tttcttttaa agatataaaa
    22021 atttcttcat tagcaaacct agctaagatt gtttctaaga gacagcttat aggtgcatct
    22081 aagttttata gttaaaatga aatattatta taataaaagc tagtaacctt gtaaaaatat
    22141 aggttactag ttttttattt attcattttc acaaaatttc agaaaactat ttacattcta
    22201 aaaaaagtaa tgtatattaa acataatgta cattataatg gataaaaagt ttctattaaa
    22261 ttactaagtt tatttaataa tcaaaataat ttatcttata ttagtatgta ttagggggta
    22321 tttatgcaaa gtttaaatga aataattgct gaaaatttaa aaaagataag gaaagaaaaa
    22381 catcttagtt tagacaagat tgcacaactt agtggtgtaa gtaagagtat gctatctcaa
    22441 attgaaaagt gtgaggtaaa tcctactata tctactttga agaaaataac taatgggcta
    22501 aaaatttcat ttacatcatt gatggagagg caggaaagtg acatagaatt gattcaaaaa
    22561 agtgatatag accattttat tgaagataat ggaaagtata taagttatcc aatatttcca
    22621 tttgactcca aaagaagatt tgagatattt atgattgaaa tagaagaagg tggaaattta
    22681 gattcaaatg ctgaacttcc aggaacacaa gagtttataa ctgtttttag tggcgaagta
    22741 accattaaaa taaatggaga agattacatt gtatctagtg gaaattctat aagatttaaa
    22801 gctgatgtat cacatatata tagaaactca ggcaaaggta tagctaaaat gagtatggta
    22861 gtatattata tataaataat ttaatggaat tagagtgata tttagatgat tttaggtatg
    22921 aagatatatt atatttaagt tataggagtg tgatttatgg atgaataata aaaaagcagt
    22981 ttttttcttt tgcagtgatt taaagaaaga cccagtagcc agtaatgtga taaaatgttg
    23041 tgaagaaata atggatttaa atcaaactga tattgttatt gatgataatt ttgtattaga
    23101 gtttaaggat aaaaacaata acttatttca ttttgtaaaa acaaaagatg taataagtca
    23161 taattataaa tattatcttc caattttaaa tagacatttt agagattatg attttgcagg
    23221 agttgtaaat tggcatgagg gagaaaatgc tccagaacat atcctaacag ctcatacaat
    23281 tggagatgtt ccaacaggag aatttggaaa ttcaaatcca agatacttta aaaatctaat
    23341 caatgctatt gaggatataa aaaatgaaaa tctacttgat gaatttacta cattaacaga
    23401 agcaactcac tggtctggaa caacatatgg tgaagaatct aaattaatta cagaatattc
    23461 tgtacctatg ttggatattg agataggaag tagtagtgat agttttaata atagtatagc
    23521 aatacaggta ttggcaaaat cattaattag agtatttgat tgtgatgaac ctttgaagac
    23581 tttgttatgt gttggagggg tacattttga gaaatctttc tcagatatta taaaaaataa
    23641 agaatataac atatcaattg gacatgtatt gccaaatcaa tggattgtaa gtggaatgta
    23701 tgatgatgaa tctggatttg agaaactaga aaagtgtata aatagcattg aaggaggaat
    23761 tgattgtata gtttttcatg ataaattaaa aggtacctat aaagagcaat gccgtaaact
    23821 aggtgaaaaa cttaatgtac ctgtatttaa acataaaata ttaaaaaatc caaaagactt
    23881 acctatatgg tagtcttata cagttaatat aacaataagt cggattaatt tttaagcgag
    23941 gtcaaaaatg atattatctt attttgcatt attaattaga gtagtgctat tagcttttga
    24001 aagagtagtt gtaagattat taggtgatga agaaggagat atttataaaa atatagcttc
    24061 atcatttcta tttttcttta tagggggagt atgtttactt ccatttagca taatggatag
    24121 agttagtgat tggtcgtttt taataccatg ttatataagt agtttagtct attcaattgg
    24181 ttcagtagcg tatgtaacgt ctttagcaac tggggaagtt tcacttgtta ctccaataaa
    24241 tagtttaaat tcattgtttt tactgctttt atcagttata tttttaggtg aaggtttaag
    24301 tttagcaaaa gttgcaggaa tcataattat gattggtgga gtgtttatat taaaaaaagt
    24361 aagttctttt ttaaagaatg tctctgtaat ttttaacaat ttaccatgta gattaatgtt
    24421 tttatacata tttttgcagt cagtaggaag agtattggat aaggcttttt ttgtacaagt
    24481 atctcctata ttatattcaa ctatactgta ttttttcgta ggtttaaatt tatttatctt
    24541 tttagcattt aaaaagaaac aaaaaataat ttgtgagatt tttactaata aaaaggggct
    24601 ttcaatttta agtggtgcta ttaatggata ttcttattta gcattattaa ttgctttaaa
    24661 taatctagaa cttagtatag cagagccatt ttctcaagta tctatgataa taactttaat
    24721 acttgctcat tttatattca aagaaaatat aaaagaaaaa ataccaggtt caattttgat
    24781 actaattggt gggtggctac tgttacttta attgacataa aaaatgaatt ataaaggtgc
    24841 tattagttag tatcagaaaa tttaaaaaag tattgacaat tcttttaggc aaatgttaat
    24901 ataataatac aaaatagtat aaatagaaga catgttactg gtaatgcagg caggatcgaa
    24961 tatattgctt tgatttttca aggtgtttat ataggttctg ccttttttgc atcttgaatg
    25021 gccattcata aaaaattatg gagaaggaga ttacaagatg aattataaaa aaactgccat
    25081 tgacattatt gaacaagttg gtggttcaaa aaatatttta gctttagaac actgttcaac
    25141 tagactacgc tttaagttga ttgatagaag taaagtcaat caagatgctt taaaaaaagt
    25201 acaaggtgtt atgagtatag ttaatggggc acaatttcaa gttgtcattg gaaatagtgt
    25261 tgttgatgtg tatgatgaaa ttttaaaagt ttgcccttta gatacaaatg atagtactgt
    25321 aaaaactgaa gaaaaaataa acttaggaac aagatttata gaatttatta ttaatatttt
    25381 tcaaccactg atttttgcta ttgcaggagc tggtatttta aaatcactgt tgatgttatt
    25441 agcaatgttt aatattttaa aatcagattc tactatatat acattattag ttgctatttc
    25501 agatgcaaca ttctatttcc tacctcttat ggtagctgta actactgcca atgtattgaa
    25561 atgtaatcgt ttagtagcta ttgccgctgt aggatactta ttgcttccag caacaacaac
    25621 tgctttaagt gaaggtgttg aactatttgg atttacaatt ccaaacattg cctataatgc
    25681 acaggttttc ccggctatct tatgtgtgtc tttcttggca acaatggaga aaatttttaa
    25741 caagtattca ccaaaaccaa ttcgaacttt ctttgttcct atgatgtctt tggcaattac
    25801 tgttccaatt actctaacta ttttaggtcc tttaggatat aacgttggta caatttttac
    25861 aaccattatt ttattcttat ataacaaaat gggattctta gttgtaggat tacttgctgc
    25921 ttttcttcca tttatggttg caacaggaat gcacaaagca ctaatacctt attcaattaa
    25981 tacaattgga aagttgggtt atgaagcttt atatatgaca tcttcattag cccacaatat
    26041 ttctgaaagt ggtgcttgtt ttgcagtagc cttgcgaaca aaagatgaaa cattaaaaca
    26101 aacagcatta tctgcaggaa tttctgcctt gatgggaatt acagagccag ctttatatgg
    26161 tattacctta caacataaaa gagcaatgtt aggtgttgta ttctcaagtg caatttctgg
    26221 taccttttta ggattatttg cagtaaaagg atttgtaatt gttggaccag ggcttgccag
    26281 tatgagtatg tttattgacc caaacaatgg aaacaatttg atttttgcga gtattggttt
    26341 tgttattgca atattaggct cgtttattat tacactgatt atttggaagg aagatacaaa
    26401 tacagtagag tcatcaattg gagatgttgt tgaagaagag ctagaagaag aaaaagaagt
    26461 aaatatctta gtaactccag tagaaggaaa agtaatagat ttaagtaagg ttaatgatga
    26521 actatttgca agtaagactt tgggagatgg agttgcaatt ataccaacca atggaaattt
    26581 atacgcacct tgtgattcag aagttgtgat gttatttgaa acaaaacatg caattggttt
    26641 aagaacaaaa aatggggctg agattttgat tcatattgga ataaatactg taagtatgaa
    26701 tggagatgga tttaaaacat ttgttaagac aggcgataat gtaaaagaag gagatttatt
    26761 aattcaattt gatttagaca aaatctcaca tgctaattta gattcaactg ttatgattgt
    26821 aaacaataat ggagcagatt atgcttataa agtgttaaac cagtcttatg gcaatgtaaa
    26881 aaaaggaagt atcttgtttg atgtaaaggg aggaatataa atatgagaaa atttccagaa
    26941 ggatttcttt ggggaggagc tacagctgct aatcaatttg aaggtggttg gaatttaggt
    27001 gggaaagggt ggtctgtatc agatgtagca aaggcacact ttgatgcaga tgtgaaagat
    27061 tataaatcta ataatgaaat cacaacaaaa gatatagaag aaggattagc acatcctgaa
    27121 gatgaagtaa attatccaaa acgtcatggt agtgattttt atcatcacta taaagaagat
    27181 attgctctaa tggcagaaat gggatttaag acatatcgaa tgagtattgc ttggtctcgt
    27241 atttttccaa atggagatga taaagagcca aatgaagaag gtttacagtt ttatgatgat
    27301 gtatttgatg agttgataag ttatggaatt gaaccacttg ttactatgtc acattatgaa
    27361 ccaccattaa atatcgtttt aaactatgat ggatggtatt cacgacaagt tatcaatatg
    27421 tttgttaggt atgtagaaac tatctgtgaa agatataaaa acaaagtgaa atattggctt
    27481 acatttaatg aagttgattc tatgattcgt catccgtaca ctactggtgg tttagttcga
    27541 gaccgtttta aggataaaaa ctttgaggaa gttatttttc aagctatgca tcatcaattt
    27601 gtagctagtg ccattgcaac aaaaatttgc catgagatta ttccaaattc aaaagtaggg
    27661 tgtatgttaa caaaattaac gtattatcca tatacatgta gaccagaaga tgttttggca
    27721 actcaacaaa aaatgagaag tatttatgca tatagtgata cgcaggtttt tggtgagtat
    27781 ccagtatatt tactgtcgta ttttaaaaat aataacattc aaatagtaaa agaagaacat
    27841 gatgatgaaa ttatgaaaaa gtatccagta gattttattt cattctctta ctatatgtct
    27901 tcttgtgagg cagctgatac aactggatta gatattacac ctgggaatac gttattagct
    27961 gtaaaaaatc cttatttaga aatgagtgaa tggggttggc aaattgattc aataggtcta
    28021 cgtatatctt tgattgaatt atatgataga tacagaaagc ctttatttat agttgaaaat
    28081 ggattgggag ctaaagatat tttaactgaa gataaaaaag ttcatgacca atatagaatt
    28141 aattatttaa aagaacactt taaatgtatg ttagatgcga ttatcgaaga tggcgttgaa
    28201 ctttggggat atacttcatg gggttgtatt gatttggtca gtgaatcaac gaaacaaatg
    28261 tcaaaacgtt atggatatat ttatgtggat gctgatgact atggaaaggg gacatataat
    28321 cgatataaga aagatagttt ttattggtat aaaaaggtaa ttgaaaataa tagtatagat
    28381 tttaaatgac caatagaagg tgagcaaata aaatgaacta cataataaag aaagttttga
    28441 actcgagcgt tgttttagtt catgatgcaa agtataatga atttattttg ctagggaaag
    28501 gaattggata tggtaaaaaa acaggagaat atatttgtgg ttccaatgat aatcaaatgt
    28561 ttgtccctgt tgaaaataca aaatcaaaac aatttttaga attaatggat gatattcctg
    28621 tcgacatttt aaagataaca caggaaataa tagtagaggc agaaaagtta ttgaactcat
    28681 cttttaataa aaacttatac ttaatattag cagaccattt taactttgca attgaaagga
    28741 tgcgtaaagg aataaaaatt acaaatcgag tattttggga aataaaaaat tattatccaa
    28801 atgagtttaa ggttggaatg gttgcaattt atatggtaga ggagagattg ggcattcaat
    28861 taccagagga agaagcagct aacattgctt tccattttgc aaatgctatg gcttcagatg
    28921 gaaattcata tgatacgatt aagtatgcca aagtaattgg agaaataatt aatatttttg
    28981 ttttttcttt gaatagaacc ttagataaaa agagtatgca ttatatgaga tttataacac
    29041 atataaaatt ttttgtggaa agattttttt cagatagtat gttaagcagt ggtgatgatt
    29101 tattatttaa tcaaatgaaa aggtcaaatc caaaagaaat gttaattgca ttaaaagtta
    29161 gagatttttt agaaaagaaa tatggaaaaa agttaacaaa tgaggaaata gctttcttgg
    29221 ttgtacatat cgcacgagtt aagcaataga gtgaattact aatattatct tatacgtcta
    29281 catggtagaa aattgaaaga aggtaaagta tataaagaaa ctgagacata ttattttgtt
    29341 gttcattatg tttattttat gagtgtatcc tgttaaaaat ttaagttaat atttataatt
    29401 aaaatataca aatagttaaa ataagtttat gtggttatga atttatttta actatttttt
    29461 tgtttaatgg aaaatatgtt ttataactag aattttattt ttaattaatt ataatacaaa
    29521 aaactttata aaatcttcag aatttcttaa agaatatgta agtaacataa gatatattat
    29581 atttagttgg taatataaag ggggcaatat ttatgaagaa taaaaaattc aatgttataa
    29641 cactgataat acttgataat catatttatg ccattaataa agagcagatt agtactaatt
    29701 caaaaagaat ttactttgaa aaaagtcgat ttttcagtga ttataagtga ataaatatat
    29761 ataaacattt aataaattta gaagttaaat gttttaatac gaaaggatac acatatgata
    29821 aatttagaag aaaagtattt aacacgaaaa gacacatata tgataaaaat tctagaatac
    29881 aatgggcata ttcgaaactg gaaagttctt tgtgaagaac ttggaatcga ttcttcatta
    29941 tgtagagatg agcgtgaacg agcaatttta gtggaagcat ataagacatg gggatatgat
    30001 atggcaaatc acatgcatgg aatgtttgct tttgcattat gggatactgt ggaaaagaaa
    30061 ctcttctgcc taagagacca gtttggggta aaacctttct attattatga gactgaaaat
    30121 gggaagcttc tctatggttc atctattcgt aagattatgg agcaaccagg atttgtgaaa
    30181 gagttaaatg aagacatgtt acagatttat atgtctttca catatgtagc aggtgaaaat
    30241 acattcttcc gtggagtaaa gaagcttatg ccaggacatt accttgtcta tcagaataaa
    30301 acagtatgta ttggtcgtta ttggaaacct gaatttcatc ctgaccacag caagtctatt
    30361 gaggaatgga cggatgaaat tcatacaaca cttcagaaaa ttatgccaga ggtaaaatca
    30421 gagaatgaaa ctgcagagtt attcctatca ggaggtgttg attcatctta tatattggca
    30481 atgtcagata tagaaaaaac aggttcatgt ggttatgagg aagagcgttt tgatgaatca
    30541 aaattagcac aacagacagc taatattctt gggtgtaaaa attcgagata tataattaca
    30601 cctgaagagt attttgcgtc agtaccttat gtaatgtacc atatggagca accaactgga
    30661 gatgcatctg ctatcgtttt tgctattgga tgcaaggcag cagctgaaaa cacaaatatc
    30721 tgttactctg gagaaggagc agatgagttt tttggtggat ataatatata ccataaggca
    30781 gagtgttatg gagagaattt gaagacattt tatattggaa atacaaacat tatgaatgag
    30841 ggtgagaaaa gaaaaattct taagaaatac aatcctgatg tgcttcctat tgaagtggta
    30901 aaaggaattt atgaagaaac agaagaacta gatacactta ctaacatgtc aaatgtagat
    30961 attcaaatat ggttggaagg agatatttat tttaatatag ataaaatgag tactgcagta
    31021 ggattggaag tcagaatgcc tcttacagat acaagaatat ttgatattgc atccagaata
    31081 ccatcagaat ataaagtgaa aggaaaagag aataaaattg cctttcgtac agctgcatca
    31141 aaaacattac cagaagagat tgcttttaga aataaattag gatttattgt gccaattcgt
    31201 atatggatgg ctgatgaccg atataataag gatatccgag ataaattcaa tagtgagata
    31261 gcagataaat tctttaacat agatgagatt aatgagattt ttaatgacta cattagtgga
    31321 aactctgata attggagaaa gatttggatg atttacacat tcctagtgtg gtatgaaatc
    31381 tattttgtaa aatgttaata caagaggaag aatcacctga aataccattc aggtgattct
    31441 taatgtttta taattttact tgctaattct tatgtctaac tcttaatggt atatcaagtt
    31501 tttttgccag ttgtttagat tcttctattt cttctggaga tatttcatct actactgaaa
    31561 aagctacttc ttttatatat tttttgcaat ctcttgcaaa atctaacata taatcaaatg
    31621 atttttctcc aaactttggt tgagtaactc tattataagc ttctttattt ggggcattaa
    31681 gacttattga tactgcatct ataacatttt ttaacagaat agctgttttt ttgttatgta
    31741 ttaaatcact tagaccattt gtatttattc ttatctttat gctacttttt tcttttataa
    31801 actttgctat ctctatcaat tcatttattc tcattaatgg ttcgccatat ccacaaaata
    31861 cgatttcatc atagtcgtct aaattgtatt tattgaaggc ttcttttact tcatctacac
    31921 ttggctcatg ctccaaccat aaactaccac tatttgcaac ttcatctttt tcgtttctta
    31981 tacaaaaaac acaactacat ggacatgtat tagttatatt tacatagata ctattttcaa
    32041 ttgtatataa gatattcata attttccctc cataaattta aattcttaat taaaataacg
    32101 ttttttaaaa tcaagtttat caagtgccat acctaagatt ataaaaacaa taaaacttcc
    32161 tattggctgt aataagccaa gtaagctcat tacaaatgca cttgtaaaac ttccaataat
    32221 tataccttca gcaaacatgt ataaaactaa tcctactata cctgctacaa ccgaagcaac
    32281 tatatttctc ttatttatta tcttgtcact tttagaagtg aaaaataata caagtattgg
    32341 ttttatgatt atagttggta ttacccagat agcagcacct gtagataaat cagctagacc
    32401 agcaccaatt gcagaagcag ctatagcata gtttgttggc aaaatagttg cagctagata
    32461 aataaaagca tctcctatat gaacatatcc attgtttcca ccaactggaa tatgtaatat
    32521 atatgctatt gtcaggcata ttatggatgc aaataatgct gaagtaacaa tataggtagt
    32581 ttttttagaa gtaactttat tcattttttc caatatactc cctccctaaa aatccagagc
    32641 taacataatt gttatgtttt cttataaata tattaatatt aatcatacaa ttttcatagt
    32701 ttgttaggtg ttttttttgt aaaatacaga ttgtacccat tcaaatgtat ataattagaa
    32761 aagtaaaaat aggtaaaatg tatagagtag gagtagttag aataagttaa tataaattta
    32821 atttggtatg aataagaaga gtacaagttt aatataaaaa ataatataag agagtctact
    32881 caatatatac tgagctgact ctcttatatt tgggaaatta aaggctattt tgttagataa
    32941 tagctaatta atgaaaaaat atatttataa aatactaatt tactctatta gtagcagttc
    33001 ctgtttttat aacttctaca gcactactta aactagaata aactatattt tcaatcgctg
    33061 tactagtgaa gaaaccaagg tgatgagtga atataacttg ttccatagaa agaagtttat
    33121 ttatttctgg gtcagttaat tctccaggat tcattttttt gtttaagaac aatccttcag
    33181 tttcaaatgt atcaagggca gcagctctaa tttttcctga ctctagtgct tctattaaat
    33241 cccctgtatt aattaaacca ccacggccag tatttactat gtaagctcca tccttcatta
    33301 tagctagagt atctttattt atcatatgtt ttgttccttc aagtaaagga gtatgtaatg
    33361 ttataaggtc agcttctttt agaaggtctt ctaaagaatc tttgtaagtt aatatatcat
    33421 ttaaatcact atttggatat tggtcaaatg caattacatt agctcctagg cctttgaata
    33481 attttgcaga agtagcacct atttttcctg tacctataac accaactgta atagatctaa
    33541 cttctgttcc aagaagttca gctatccaac ggtaatcacc ttcacagact tttttcttta
    33601 ctagaggagt ctttcttaaa aggttcatag cttgagtaac agctaattca gctattgcat
    33661 taggtgaata agaaggaacg tttgtaacga taagtccatt ttcattaact aaatcaaaat
    33721 gtatcatgtc aacccctgca gttcttgaag ctataacttt aaccccagca tcttttaaag
    33781 tttcataaat ataaggatta tctatatagt tagtttgttg tatagatata ccatcatacc
    33841 ctttagcttt aactacattt tcttcagtca tgttttcagg ataaatatcc acttgaacat
    33901 ccttatgttc ttcagaccat ttttttatta ctggttcttc ataatcgcgt gctccaaata
    33961 ctagtatttt catatcaata ccctcctgta attattaaat tattatggta atttttcatt
    34021 tagaaataat atgtagcata taaggttata ttttttatac aaaattttta aggttaaaaa
    34081 tttagttttg aaattgtttt ccctgtgtta ttttgatatt tagtaatttt ttatttaatg
    34141 taataattac tctaaaattt atcaaagaaa ttgttatttt ttagattaaa tattattaaa
    34201 aaattatcta agtttgaaat tagttaacta acttgctgat taattacaat gataacatgt
    34261 gtttttgagt ttagcaatga aaactttttt tgaaatgtca agctttttca taaaaaaata
    34321 tataaaaaaa acttttataa gcatagaaag aatagcaaaa tgcaatggat agtggcaaga
    34381 tgccacgata tgaaaaagat tattcaattg catattgtta aaaaacattc aaatcaagcg
    34441 atattttgat taaatataaa gttggcacga taaatgctta acaatatagg tgtaagacaa
    34501 taaaacaata aaaaataatt ttaataattt ttaagttatt ttagataaga ttaggaactt
    34561 tgacatcaga cagttaatat cagaaaaaag tattttatga gtgatttaat cgaaatttta
    34621 taattgatac tattaaggag gaaaacgtta tgcttttaga aggagttaaa gtagtagaac
    34681 tttcaagttt catcgcagca ccatgttgtg caaaaatgtt aggtgactgg ggtgcagagg
    34741 ttattaagat tgaacctata gaaggtgatg gaataagagt tatgggtgga acatttaaat
    34801 ctccagcatc agatgatgaa aaccctatgt ttgaattaga aaatggaaat aaaaagggtg
    34861 taagtattaa tgtaaaatca aaagaaggag tagaaatatt acataaatta ttatcagaag
    34921 cagacatatt tgtaactaat gttagagttc aagcattaga aaaaatgggt atagcttatg
    34981 accaaataaa agataagtat ccaggattaa tattctctca aatattagga tatggtgaaa
    35041 aaggaccttt aaaagataaa ccaggatttg actatactgc atacttcgca agaggaggag
    35101 ttagccaatc tgttatggaa aaaggaacat ctccagcaaa tacagcagca ggatttggtg
    35161 accactatgc aggtctagca ctagcagcag gaagtttagc agcattacat aaaaaagctc
    35221 aaactggtaa aggtgagaga gtaacagtaa gtcttttcca tacagctata tatggaatgg
    35281 gaacaatgat aacaacagca caatacggaa atgaaatgcc tttatcaaga gaaaatccaa
    35341 acagcccatt aatgactaca tataaatgta aagatggaag atggattcaa ttagctttaa
    35401 tacaatacaa caagtggtta ggcaaattct gtaaggttat aaatagagaa tatatattag
    35461 aagatgatag atataataac atagattcaa tggttaatca tgttgaagat ttagttaaga
    35521 tagttggaga agctatgtta gaaaaaacat tagacgagtg gtcagcttta ttagaagaag
    35581 cagacttacc atttgaaaaa attcaaagct gtgaagattt attagatgac gaacaagctt
    35641 gggcaaatga cttcttattt aagaaaacat acgatagcgg aaatacaggt gtcttagtta
    35701 atactccagt tatgtttaga aatgaaggaa ttaaagaata tacaccagca ccaaaagtag
    35761 gtcaacatac tgtagaagta ttaaaatctt taggctacga tgaagagaaa ataaataact
    35821 ttaaagatag taaagttgta agatattaat tagtaattct agatttttta aaaggagaat
    35881 gctaaagatg tacacaatgg gattagatat aggttcaact gcatcaaagg gagtaatctt
    35941 aaagaatggg gaagatattg tagcttctga aacaatatcc tctggtactg ggactactgg
    36001 accatcaaga gttttagaaa aattatatgg caagacaggt cttgcaagag aagatattaa
    36061 aaaagttgta gttacaggat atggaagaat gaactattca gatgctgata agcaaataag
    36121 tgaattaagc tgtcatgcta gaggggtaaa tttcataatt ccagagacaa gaaccattat
    36181 tgacataggt ggtcaagatg caaaggtatt aaaattagat aataatggaa gactattaaa
    36241 ctttcttatg aatgacaaat gtgctgcagg tacaggaaga tttttagatg taatggcaaa
    36301 aataatagag gttgatgtat ctgaactcgg aagtatatct atgaattctc aaaatgaagt
    36361 atcaataagc agtacatgta cagtatttgc agagtctgag gttatatcac atttatctga
    36421 aaatgcaaaa attgaagata tagtggcagg tattcatact tcagtagcaa agagagtttc
    36481 tagcctagta aaaagaatag gagtacaaag aaatgtagtt atggttggtg gagttgctag
    36541 aaatagtggt attgtaagag ctatggcaag agaaatcaac acagaaatta ttgtacctga
    36601 tatacctcaa ttaactggtg ctttaggagc agcgttatat gcttttgatg aagcaaaaga
    36661 atcacaaaaa gaagtgaaaa atatataaaa agagggatga aaatgtctga aaaaaaagaa
    36721 gctagagtag taattaatga tttattagct gaacaatatg caaatgcatt taaagctaaa
    36781 gaagaaggaa gacctgtagg ttggtcaaca tcagtatttc ctcaagagtt agcagaagta
    36841 tttgacttaa acgtattata tccagaaaac caagcagctg gagtagcagc taaaaaaggt
    36901 tctttagaat tatgtgaaat agctgaatct aaaggatatt ctattgacct atgtgcatat
    36961 gcaagaacaa attttggtct tttagaaaat ggtggatgtg aagctttgga tatgccagct
    37021 ccagatttcc tactttgctg taacaatata tgtaaccaag ttataaaatg gtatgaaaat
    37081 atttcaagag aattagatat acctttaata atgattgata caactttcaa taatgaagac
    37141 gaagttactc aatcaagaat agattatatt aaagctcaat ttgaagaagc tataaaacaa
    37201 ctagaaatta tatcaggaaa gaaatttgac cctaagaagt ttgaagaagt aatgaaaata
    37261 tcagctgaaa acggaagact atggaagtat tctatgagtt taccagcaga ttcttctcct
    37321 tctccaatga atggatttga cttatttact tacatggctg taatagtttg tgctagaggt
    37381 aaaaaagaaa ctacagaagc atttaagtta cttatagaag aattagagga caacatgaaa
    37441 actggtaaat cttctttcag aggggaagaa aaatacagaa taatgatgga aggtatacct
    37501 tgttggccat atataggata caagatgaaa acattagcta aatttggagt taacatgaca
    37561 ggtagtgttt acccacatgc ttgggcatta caatatgaag ttaatgattt agatggaatg
    37621 gcagtagcat atagtactat gtttaacaat gtaaacctag accgtatgac aaaatataga
    37681 gttgattctt tagtagaggg taaatgtgat ggagcattct atcatatgaa cagaagctgt
    37741 aaacttatga gtttaataca atatgaaatg caaagaagag cagctgaaga aactggatta
    37801 ccatatgctg gatttgatgg tgaccaagca gaccctagag ctttcactaa tgctcaattt
    37861 gaaacaagaa ttcaaggttt agttgaagta atggaagaaa gaaaaaaact taatagaggt
    37921 gagatataat ggaagctatt ttatctaaaa tgaaagaagt agttgaaaat ccaaatgcgg
    37981 ctgtaaaaaa atataaaagt gaaactggta aaaaagctat aggttgtttc ccagtttatt
    38041 gcccagaaga aattatacat gcagctggaa tgcttccagt tggtatatgg ggagggcaaa
    38101 cagaattaga tttagctaaa caatatttcc ctgcatttgc atgttcaata atgcaatcat
    38161 gtttagaata tggattaaaa ggtgcttatg atgaattatc tggagttatt ataccaggta
    38221 tgtgtgatac actaatttgt ttaggacaaa actggaaatc agcagtacct catataaaat
    38281 atatatcatt agtacaccca caaaatagaa aacttgaagc tggtgtaaaa tacttaatca
    38341 gtgagtacaa aggcgtaaaa agagaacttg aagaaatttg tggatatgaa atagaagaag
    38401 caaaaattca tgaaagtata gaagtttaca atgaacatag aaaaactatg agagactttg
    38461 ttgaagtagc ttataaacat tctaatacta taaaaccatc aataagaagc ttagtaatta
    38521 agagtgggtt ctttatgaga aaagaagaac atactgagct agtgaaagat ttaatagcaa
    38581 aattaaatgc tatgccagaa gaagtctgtt ctggaaagaa agttttatta acaggtatat
    38641 tagctgattc taaagatata ttagacattt tagaagacaa caatatatca gttgtagctg
    38701 acgacttagc acaagaaaca agacaattca gaacagatgt accagcaggt gatgatgcgt
    38761 tagaaagatt agcaagacaa tggtcaaaca tagaaggatg ttcattagct tatgacccta
    38821 agaaaaaacg tgggtcactt atagtagatg aagttaaaaa gaaagatata gatggtgtta
    38881 tcttctgtat gatgaaattc tgtgacccag aagaatacga ttatccttta gttagaaaag
    38941 atatagaaga tagtggaata cctactttat atgttgaaat cgaccaacaa actcagaata
    39001 atgaacaagc cagaactcgt attcaaactt ttgctgagat gatgagttta gcgtaagttc
    39061 attaaaataa atttactata aaatatgaaa attggaggaa gctatgttat ataacaaaga
    39121 acaagaactt ttaagaaaag cagtaagaga ttttgttagt aaagaattag atactttacc
    39181 agcagaaatg gataaaacag gtgtaatgcc taaggaatta atcaaaaaat tagctgatgc
    39241 aaaatttata agcagtaata tcccagaaga atatggtggt gggggagcag gatatgtttc
    39301 ttacgctata gtaatggaag aaatagctag aagatgtgct tcaacagcta cttttgttac
    39361 agctggttct tctcttgctt cattaccaat actttacaat ggtactgaag agcaaaaaca
    39421 aaaatactta aaaggtatag caacaggtga attaatagga gcatttggtt taactgagcc
    39481 aggagctggt tctgatgcag gtggacaaca aacaacagca gaattagttg gagaccacta
    39541 tatattaaat ggtagaaaaa ctttcataac taatggacca ttctgtgatg tagctatagt
    39601 aatagcagtt acagatagaa gtaaaggact tagaggaaca tcagcgttta tagtagaaag
    39661 taaatgggat ggtttctcaa caggagctca tgaagataag atgggtataa gaggaactga
    39721 aacttctgac ttaatatttg aaaacgttaa agttccaaaa gaaaacttac ttggaaaaga
    39781 aggtcaagga tttaagatag caatgggtac tctagaagtt ggtagaatag gtgttgctgc
    39841 cttagctcta ggaatagctc aaggtgcttt agatgaagct gttaaatata caaaacaaag
    39901 agttcaattt ggtaagccta tagctaaatt ccaaaatact caatttacta tagctgacat
    39961 ggaaacaaaa gtttgtgcag ctagaggatt agtttatgat gcagcacaaa agagagatgc
    40021 aggaatgaga gttgctcaag aatctgctat ggctaaatac tatgcatcag aaattgcaaa
    40081 tgaagttgct tataaagcat tacaacttca cggtggatat ggatttataa aagattatga
    40141 aatcgaaaga atgtacagag atgctagaat cgtatcaata tacgaaggaa catcagaagt
    40201 tcaaaaaatg gtaatttcat caaacgtatt aaaataataa ataatctaat gaaattggag
    40261 gtatagactt tgaaaatatt agtttgcgta aaacaagttc cagatactaa cgaagtaaga
    40321 ataaataaag aaacaggtac tcttataaga gatggagttc caagtatatt aaacccagat
    40381 gatgcaaatg cattagagga agctttaaaa attaaagatg agcatgatga tgtaactata
    40441 acagttataa caatgggacc tcctcaagca gactttatgc taagagagtg tttagctatg
    40501 ggtgctgatg atgcaatatt attaagtgat agagcatttg gaggagctga tacttgggct
    40561 acatcaaata ctattgcagc gggaatatct aaagtaggtg actatgacat aatatttgca
    40621 ggaagacaag caatagatgg agatactgca caagttggac cacaaattgc agagaaatta
    40681 gacattcctc aagttacata tgtacaagat ttcaaaatag aaggaaaaga tataatagtt
    40741 caaagacaat tagaagatgg atacgaatta ataaaagtaa gtacacctgt acttttaaca
    40801 gcagtaaaag agttaaatac acctagatac atgtctgttg ataaaatagt aaaagcatat
    40861 aaacatgatg taaaagtttg gacaattgat gatttagatg taaataaaga agaagttggt
    40921 ttaaaagcat caccaactaa agtatttaga tcatttactc ctgaaccaag aggaaaagga
    40981 gaaatcttag aaggtaaagc tgatgaaata gctagtaaaa taataatcgg tctaaaacaa
    41041 aagcacatta tataagttgg aggagtacaa actatgaatg atataaaaga tttaagttct
    41101 tataaaaacg tatggatatt tgcagaacaa agagaaggaa aaatagctcc agtagttata
    41161 gaattattag gagaaggaag aaaattagct aaagaagtag atgcagaact ttgtgcaata
    41221 ttattaggaa aagatgttga tggattagct aaagaattaa tcacttttgg agctgacaaa
    41281 gtttatgttg cagatgatgc tcttttagaa aaatatacaa ctgatgcata tacaaaagta
    41341 ataaaagatg caatagatga aataaaacca gaaataatgc ttttcggagc aactcatata
    41401 ggtagagact tagcacctag aatagcttca agagttggaa ctggattaac agctgactgt
    41461 actaagttag aaatagaccc agaagataag aaaataaaac aaactcgtcc agcatttggt
    41521 ggaaacataa tggctacaat catttgtcca aaccatagac ctcaaatgtc tacagttaga
    41581 cctggtgtta tggataaagc tgaaaaagac gaaacaagaa ctggtgaagt tatagcatta
    41641 gactacaaaa taactcaaga tgatataaga actactgttt tagaaacagt taaaactaag
    41701 aaagatttag tatctcttac agatgcaaat gttatagtat caggtggtct aggattaggt
    41761 ggaccagaag gatttgaaat gcttaagaaa ttagctgaca aattaggtgg agtagttggt
    41821 tcttctcgtg cggctgttga tgctggatgg atagaccatt ctcaccaagt aggtcaaaca
    41881 ggaactactg ttaaaccaaa cctatatata gcttgtggta tatcaggagc aatacaacat
    41941 ttagcaggta tgcaatcatc agatttcata attgctataa acaaaaaccc agcagctcca
    42001 attttagaaa tcgctgacta tggagtagtt ggagacttac atgaaatagt tccaatgctt
    42061 atagaaaaat tagatagcgt tgatgattta ttagaagcta taaaagctta atagatacaa
    42121 actatataaa tattactgat tgaataagtc ttattagtta gtaacataat tattaaccct
    42181 ttgataagtt attgctagtg tgtatttgtc agttattaaa aagtctgttt gaataaaatt
    42241 ttataataca agataatctg gataatcctt atatgtatat tgcttacaaa ttgtgagtta
    42301 tattctgtaa ggattatctt tgttttttta aataaatctt aaatttaatt aaattgtatt
    42361 aaatagacaa ataattacta aatatgtgat aaaatacaat taaaagcaaa atgaaatttt
    42421 taacaaacta taatcattaa aattatatct tagttacgtt ttaatgaaat aaactacttg
    42481 aaaagacgaa tattataagg agttgattat atgtgctgat ggtatttatt gtaagcaaac
    42541 aataaatttt gtatgtagtt caataaatta cttaatgaaa ggtgcgaata ttaatggata
    42601 ataatttaat agggcttata gaacatgtag aaaatccagc cattttatgt aaagaatcag
    42661 gcgaaataat atactgtaat catctaatag atagtatttt tagttttcta gatataaaaa
    42721 agcctagaaa tataaatgaa ttagattcaa attttgacaa aacagaaata ctgacagata
    42781 gtaaaaagaa aatagctttc agagagttaa ggatgactgc acatatatac aatatgaaag
    42841 ataataataa tgaaaataat atagtttatt tatttgagaa gtctctaata tctgataaag
    42901 taattgaaga tataatagag catatagatg aagttgttgt tgtgtttaac aaagatgggg
    42961 taattgaaaa gatgaacact gtcagtgatg agatattacc ttttaaaaga actgaggtac
    43021 ttggtagaaa tataacagac cttgtgagac aaggattagt tgaagaacca ataatattaa
    43081 acatgcttaa agtgaagaaa aagatttata gaaatatcgt ttacccagat gggaagctta
    43141 ttgcatatac ggcagttcca agatgggatt ctaagggaaa gcttacagga ggagtactaa
    43201 cagggagaga tatttcaagg gttattaagc ttgaatctca gataaaatat agtgatatat
    43261 cagaagacac agagtatata agtcaaagta agattatgga caatataaaa aaagttgtta
    43321 agagagctgc agcctcagat tcttctatat ttataaatgg agaatcaggt gtaggaaaag
    43381 aaataatagc aagaacaata tataagtata gttcaaggag agacaaacct tttatagcta
    43441 taaactgtgg agctatacca aatgaattat tagagtcaga gttttttgga tatgaagaag
    43501 gttcttttac tggagctaag aaaaaaggta aaaagggact ttttgaagag gcgaatggtg
    43561 gaactatttt cttggatgag ataggtgagt taccaatgca gatgcaaaaa aaattactta
    43621 gggttataca agaaaatact attactagaa taggtggtag taagcctata aaaatagatg
    43681 ttagatatat aagtgctact aatatttctc atgaagacct tagaaataac cttaaattta
    43741 gacaagattt gtactataga ttaagtgtta ttccagtaaa aatacctcct cttagagaaa
    43801 gaaaagagga tatagtacca ttagtaaatt atttcttaaa actttacaat gaaaagtaca
    43861 atagagaagt agaagtttcg cctaaagtta ttgagttatt agaagaatat tcttggccag
    43921 gaaacataag agaattaaaa aacatcattg aaagatttgt agtattatca gctaaaaatg
    43981 taattggaga agatgaattt aacatgctga taaatttaga tatgattgat aatgaaacag
    44041 atgatttatc accaatagtg gtaaatggaa ttatgaatct taatgatgca tataaaatag
    44101 tggaccaaat aatgataagt aaggctataa ataagtatgg ttcaataaca aaggctgctg
    44161 aagttatagg tatatatcct tctaccatcc atagaaagat aaagagtgga catattcacg
    44221 tttagctgtc agtttaaaaa gacaatataa ttaaaatatt ataagataca taatttatac
    44281 aacttaaaag agatggctta aaaataaatt taattacttt aagtcatctc ttttctttta
    44341 taaatattta aaagttatat tagtttatag agttagcaga acctaaaaca tcatctatct
    44401 tgctttcaac tacagcttgt atagcatctc taccagcacc aatgtatttt cttgggtcaa
    44461 attcttttgg attttcagct aagaattttc tgatagcagc agtcatagct agtcttaagt
    44521 cagtatccat gtttatttta caaacagcca tagaagatgc ttttcttaac atatctacag
    44581 gtacaccttt agcaccagct atatttccac caaattcatt acatgtagca acagcgtttt
    44641 ggtcaacagc agatgcacca tgaagaacta ttgggaaacc tggtaatttg ctttggattt
    44701 cttctagtat atcgaatctt aatttagctt ctcctttgaa tttgaaagca ccatgagaag
    44761 ttccaatagc tattgctaat gaatcaacac ctgttctttc aacgaactca actgcctcag
    44821 ctggttgagt atacttgtga acatcagaag taacatcatc ttctgttcca gctagaacac
    44881 caagttctgc ttcaacaaca acacctttag agtgtgcata ttcaacagct tctttagtta
    44941 ttctaacatt ttcttcaaag tcaaaatgag aaccatctat cataactgaa gagaaaccag
    45001 catcaataca agttttaata gcatccatat ttggaccatg gtctaagtga agagctacat
    45061 ctacacctat ttcatcagaa gcagccttaa ccatttcaac taatgtatga ggtccagcat
    45121 atttaacagc tgacatagaa gcttgtatca taacataaga atttttagct ttagcagctt
    45181 ttaaaacacc ttgtaattgt tctaagtcac ttatgttaaa tgcacctata gcaaatccac
    45241 cttcgtaagc ttttttaaac atttcttttg tagtaattaa tgccatttta aactcctcct
    45301 attaactttt aaaatttacc catcacttat attataacgt taaatcaaaa aaagtatata
    45361 gtaaattgta ataactataa attacaagta taatgttaaa tagaagacaa taggattaaa
    45421 taaaataata aagaatataa acaatttagg aaaactagct atataatgct aactataagg
    45481 gtaggaacta ccttattagt ttggagatac tgataacaat agttgccttg accaagaagt
    45541 taccacttca aacgttatcg aaaggaatta agtggatgat aattcactaa aaatttaaaa
    45601 taaaggagat aaactatgcc acagataaaa ataagaggaa ttaatgaaaa tgatatatgt
    45661 aaaataagtg aaaaaatgat aaatgattta gttgaagctg taaaatgtcc aagagactac
    45721 tttgaaatag aatgtataaa gtcagttgca ataagagatg gtaaaatagc agatgtatat
    45781 ccttttgttg aagtagcttg gtttgataga ggacaagaag tacaagatat agtagcaaga
    45841 ataataactg atagtataag aaataattta gatgtagaaa gtatagattt agcatttaca
    45901 gtatttgaaa aagaaaaata ttatgagaat ggagagcatt tttaatggct aaaaagcaac
    45961 gtatagataa aattctttca aatttaggtt atggaagtag aagtgaaata aagaagtatt
    46021 gtaaacaagg gtctgtagta gtaaatggaa gtgaagtttc aaatccagga actcaagtag
    46081 acactgaaaa tgatgagata ttatttaatg gagaagaagt tatatataga gaatatatat
    46141 atttgatgat gaataaacct gatggatata tatcagcaac tacagataaa tatgacccaa
    46201 cagtattaga tttaattgat ttatcatact tagcttttga accatttcct gttggaaggt
    46261 tagataaaga cacagaggga ttattagttt taactaatga tggaaagctt tctcatagag
    46321 ttttatctcc taagaagcat gtgcctaaga cttattatgc aaaaattgat ggagtagtta
    46381 ctgaagaaga tgtagaagct tttttagaag gtgtagtgct tgatgacgga tataaaacta
    46441 tgccatcaca gttaaatata ttaaaaagtg atgatgaatc agaaatagag cttacaatac
    46501 atgaaggtaa gtttcaccaa gtaaaaagaa tgtttgaaag cgtaggcaaa aaagtagtat
    46561 acttaaaaag attgtctatg ggcaatttaa aattggatga aagtttagag ttaggtgagt
    46621 atagagagtt aacagatgaa gaagtaaaat tgattgaaga aagataataa agatactata
    46681 gtaaattgga ggaatgtctg tgaagaaaaa agatgttata gaatttgaag tagataaaat
    46741 ggaatttggt ggtacatctt taagccaagt tggagataga gttatccata tgaagggtgg
    46801 aataagtggt caaaaggtga gagctggagt taaaaaagtt agaagtaaga aagctgaagt
    46861 taagatgata gaattattag agaactcacc acttgaaact gaagaaactt gcaagcactt
    46921 tagagagtgt ggaggatgta cactattgtc tgtgccatat gaaaaacaat tagaaataaa
    46981 agaaaaacaa gttatggatt tatttttaaa gcaagattta tttggatttc agtttttagg
    47041 gatagaagga agtccagaaa acaaatatta tagaaataag atggaatata cttttggaga
    47101 tgaagtaaaa aatggacctt tgacattagg tcttcataaa aaaggaaagc atatagatat
    47161 acaaactgtt gaggagtgta tgttggttga tgaagacttc tcaaagatat tagtttctag
    47221 tgtagagttt ttcaatgaaa aaaagcttcc ttattataga acaatgaatc acaaaggata
    47281 tttgagacat cttgtagtta gaaaagggat tcatactaat gagattatgg ttaatatagt
    47341 aacttcttct caagaagatt ttgatatgta tgagtttaaa gatatgcttt tagggattga
    47401 tttaaaagct gagttagtag gtgtacttca tactattaat gatggtttag cagatgcagt
    47461 ccaatgtgat gagttaagag tattgtatgg aagagattat atacaagaag aaattttagg
    47521 tcttaagttt aagatttcac cattttcgtt tttccaaacc aatactaagg gagcagaggt
    47581 tctttatagt attgctaggg attttattgg agattacaat gataaagttg tatttgactt
    47641 gtatagtggt actgggtcta ttggacaggt tatggctggt gctgctaaga aagtgtatgg
    47701 tattgagata gttgaggaag ctgttgttgc tgctaatgag aatgctaagt tgaatggact
    47761 tactaattgt gagtttattg ctggggatgt ggctaaggtt gttaaggatt taaaggacaa
    47821 gcctgatttg attattgttg accctcctag accaggcatt cataaggatg ctattaggga
    47881 tatttgtgga tttggtgcta aggagattgt ttatatttct tgtaatccta agtctttggt
    47941 tgttgatttg gttgatttta aggggtatgg ttatgagatt aagatggtta agtgtatgga
    48001 tatgttccca aatacgccac attgtgagac tgtagtgttg ctacgtcgaa aataatgcta
    48061 gaaatcttga gctttagaca gtttcataga catataatat ttagattaga gggtaataaa
    48121 attaggaata aagaattgaa aaggtgtttt gatgtgtctg tagttatata tatggagtgt
    48181 gggaatacga aataaaaaaa gttttaatta tagaaataga tattaaattt ataaatttaa
    48241 tatctatttt ttatgtgaaa atatatttaa tctaaagaat gatatttcat aaaaaaaatt
    48301 aaatatattt ttaaaatatt tacaatagag ttatttttta ttcgtataat aatagaaata
    48361 ttttagcata agatgtataa taaaggaaaa aatacagaat taaaaaacat aagatagata
    48421 agtggactta ggggagagaa attattatgc aattgacaaa aataattctt agtaactata
    48481 ggtgttttgg agaagaacct acaactattg aaattaataa tttaactgga tttataggtc
    48541 ataatagcag tggtaaaact gctttattaa gtgcacttat gaaacttttt ggagaaaagt
    48601 ctagtgatag aattattgaa agatcagatt tccatatacc tgaaagtatt gatccagata
    48661 gtatttctaa gaatgaatta tatattgaag cacaatttga gtttcctgaa ttggagagag
    48721 gtaaagacag catatctata ccagtatttt ttaaaaatat ggttgttagt gaaccaggtg
    48781 ggaaacctta tttaagaatt agacttgaag caaattggga gaaaagctca aatcctgaag
    48841 gaagtattga ttcaaatgta tactatataa catctacaac agaggagata aatcctgaag
    48901 ataagcgtaa tatcaaaaga tatgagcttg atcaaataaa gatgatttat gtacctgcca
    48961 ttaggagacc agatgaacag ttaaaaaatg tctcaggaac aataatttca agattattaa
    49021 atggtataag ttggtcagaa caaacaaagg caagaattaa aacgaaagca agtgaaacgg
    49081 aggaaatttt ctttgaagaa aaaggggttg aatcattaaa gaaatcactc gaaactcaat
    49141 ggaatagtta tcataaggat attagatatt ctaatccaaa gataaacttc aatagtactg
    49201 atttagagac aattttaaaa aaagttgaag taactttttc acctacaggg acacatcgag
    49261 attatcgggt tgaagagctt ggagatgggt tacgttcttt attttatctt tcacttgtaa
    49321 atacattttt agaaattgaa gaagaaattc taaaatctat taatgatggt aaagaagaag
    49381 atatatttac attaataccg cctgtattaa caattgttgc ggttgaagaa ccagaaaatc
    49441 atatttcacc tcatctttta ggaagggtag ttgaaaaatt aaattttatt tctacaaaag
    49501 aaaattcaca gacaatattg acatcacatt caccagcaat agtaaaaaga attgaaccaa
    49561 cagacataag gtattttagg atttgtaagg aatatgaatg tacaaaagtg aagtcaatta
    49621 tattaccaaa tgaagaaaag gaagcagaac aatttaaatt tgtaaaggaa tcagtattag
    49681 catatcctga actttatttt gcaaaacttg ttgtattggg cgaaggtgat agtgaagaga
    49741 tcattattaa gcagatgatt gaattaaaag cagaatctgt agattcatca gaaatttcaa
    49801 tagtaccatt aggtggtagg catgttaatc atttttggcg tttattaaat gatttagaaa
    49861 ttccatttat tactttgtta gatttagata gagaacgaga tggaggtggt tggggacgta
    49921 taaagtatgc aatacaacaa ttaataaata ttggtcatga taagaatgta ttactttata
    49981 catgtgaagg aatttcacaa gataatgaat ttaaagagat gcatacttgg gatgtaactg
    50041 atactgaaaa tatggctaaa tggattgaaa tgctaaaagg ttatgatgtt tatttttcag
    50101 ctccgttaga tatagatttt gcaatgttac aaagttttaa agataaatat atttcagcat
    50161 taacaagtgc ggaaggtcct aggataaaag atcatggaaa aatacaagat attgtgatca
    50221 atgaagatgc tgaagatgaa tcattgaaag ctgcttataa agatagaata gatagtgata
    50281 ttaaatcaac cttaaaacaa gaaggtggtg atggatctac ttatactgag ggagagaaag
    50341 aactaatgat atggtattca tatttctttt taggaagagg taaaccaact actcatttat
    50401 ctttattttc taataatact gatatagatt ttgaaagttt tccatactgt ctaaaggagt
    50461 ttgtaaatag tattattgaa aagatgatag atgattcagg gggtggaaga aaatgaagag
    50521 gaattgggtt agtaaagaag attggagtcc agcggctgga ttcagactag aagttgaagc
    50581 gatgaataca gttattaatg ataagaatac acttgttgta gctggtcctg gcgctggaaa
    50641 aacagagtta ttagctcaga gagcctgctt tttactagag actaatacct gtagatatcc
    50701 taaaaaaatc cttgctatta gttttaaaaa ggatgctgct gaaaatttaa aagagcgttt
    50761 agaattgaga tgtgggaaag aattagcttc aagatttgaa tcaaagacct atgatgcttt
    50821 tgcaaaagaa atcgtagata gatttagaaa tagtttagat gaagcatata gacctttaaa
    50881 taattacaat atagctgaaa atcgtgatgt tagaagagca tttgagatag caggattaaa
    50941 tttcagagga aatcaaactg aatttaataa agtatatgga aataaactat cgataaataa
    51001 attgccttta catacagatt ttgtagataa gatttttata gatgcttgga atgtactact
    51061 taaaggcaac aaagatacta attttgtaag ttcacttact tttggtatga tatcacgttt
    51121 agccgaatat ttgataagaa ccaataggta tattaagaaa gcaattgaaa tgacttatag
    51181 tcatgtgttt ttagatgagt ttcaagatac taaatctatt caatatgatc ttgttaaagc
    51241 ttgttttttt aaaacagaaa caataattac tgctgtaggg gatggcaaac aacgaattat
    51301 gttatgggct ggtgctagaa agtcaatatt tgaagatttt caaaatgatt ttttaagtca
    51361 aaaaagaaca ttaattatga atcatcgttc agcgccaaga cttgtagaga ttcaaaaagc
    51421 aatgtataac agtttgaatg aagaggcaat tgatttaaaa actaatgaaa agtggaatta
    51481 tgaagatgga gaagtgtatt taagactttt tgaggattat ataaaagaag ctgatatact
    51541 tagtgaggaa atagtcgaat tggtggaaac aggtatagaa attaatgaaa tatgtatatt
    51601 agtaaaacag agcgtagata tttattcaaa agagattata aataaacttt ctgaacgtaa
    51661 tattaaggcg cgtaatgaag caatgtatca ggagatatta aaagaagata taataaagac
    51721 actggtttcg ctttttaggt tgtcgttaag tgatagaaat cccgatgatt gggattatat
    51781 ttacgatatt ctaggtgaat tatatggaat agacgaaggg tataacccta aaatattaaa
    51841 tgatttcatt accaaagtag aattaatgat taatgatctc aaggtaaatt taaatattac
    51901 tgatgaaaaa caattttcag atttagttga ttctaaggtt gaatatattt catatgaaaa
    51961 atttgcatca aagtttcaaa aatataaatc taaagattat tttgatgatt tggtagataa
    52021 atttaaaaag ctggtatgga ttgaatataa tgaaactaaa gattggatta aagcgattga
    52081 taactttgaa ggtaaaaatt caattccaat aatgacaatt cataaaagta aaggacttga
    52141 atatgatact atcttttttg ttgggttaga agattcagca ttttggaatt ttaaaaatca
    52201 accagatgaa gatagatgtg cattttttgt tgcattatca agagctaaaa gaagaattga
    52261 ttttacattt agcttagata gaccagcagg attttcgaat tcacagaagc attattgtat
    52321 taatgaattc tacgaattgt ttgataatac tgagattgta aaaaagatag agtattgatt
    52381 aagatgataa aaactttagt atattatatt ttaagatatt agttatataa gtagacattg
    52441 aatttatgta tttgatgtct attttttata taaaaatata ttaaagaaag gatgaatttg
    52501 catgaagaaa aaaacaaaaa tatctaaaaa gattgtaagt tttattatgg tttttataac
    52561 tatagttact actatactta catcatcagt ttcagcttat gctagcgagt tggatatgag
    52621 tgaacagaca ggctttaatt atttaggtat tagtccaatt acaggaaaaa aattaatcat
    52681 aacatttatc gtatgaagat ggataataaa attgtatttt gtgtagagcc aggaattaaa
    52741 acttcaagtg gaggaggata tatatcggag gagttaggag ataaatttat atctacaaca
    52801 cttccaaatt atcataaaag aaaagctgaa atacttgaga aggtaaatag acataatata
    52861 ttaccttcat ggaataatga aaaagttgca gttaaaagtg gagaaacaat tgagttagaa
    52921 gataagaatg gtattattag agaaatgcaa ttagaatcaa ataatactgg aacagatata
    52981 ttacttgaag aaaatacttt gaaaattaca gcaaataaaa attctaattc aggagttatt
    53041 agttatataa agattcctaa aaatgaggtt ggaatatcaa tagtttatcg taagcataac
    53101 tatcaaagct tatcagaatt tcatatggaa agttcgatga gtgcaaattt aaatataaat
    53161 gtaatcaagt taggaattgt taaagtaaaa aagattgatg aaggcacagg aaaggaatta
    53221 gcaaatgcaa aacttagatt tgagtatgat ggtgatagta aagaaattat aacgggttct
    53281 aatgaaattg ctagtataga agatattatt ggttgattaa aaagtgaagt atacttttgt
    53341 atctatgaaa aagactataa gcaatatata aaattagata tacctattga tgaagcaaaa
    53401 ataaaaaata gatttgaaat aaggttaaaa aatgaaagag catatcatgc agcagttgat
    53461 ttgttagcaa atagagatga agaaaagaca gcattttcaa ttattaatcg ttatatacgt
    53521 tttgttgata aagatgatga aaaaattaga agtgaatgga aaactaatga tcagtggagt
    53581 tattttattg gtgaaggtag agcgaagtta aaactaacaa caaatccaga accatataat
    53641 attcaaaaaa ctttaaattg gttatcaaga caagttgcac caacgttaaa aacaattaaa
    53701 aggttagata gtttgaacaa ctcaacatta attgagggct taataaggta tgcaagacta
    53761 acagataaac ataaaaaaat aattgaacaa aattcagtaa atgttgaaga cattatttat
    53821 gatgaataaa aaaatgtaat tagtattgca gattttaata taaaagaagg gagatatacg
    53881 aatgaatttt ggtcaaaatt tatataatta gtttttatca aatgcacaat cattggtatt
    53941 aatggctata gctataattg gtgtatattt aggatttaag agagagtttt caaaacttat
    54001 aggattttta gtagttgcat taattgcagt agggcttgtg tttaatacag caggagttaa
    54061 agatatatta ttggagctat ttaataaaat aataggtgtg taaggattaa aagagaatag
    54121 aaaattatga gtatatgatg aagggttcta ataagtttta ttaaaatata tattgaaaga
    54181 caagtagagc tatttcgagt tattacatgt aatgctaata tatataactg cattttggaa
    54241 attaaataca taattagaaa tagcaaattt tataggtgac ttattaatat gtttacttat
    54301 tgtatactat ttgatatatt taatatgagg tgattcttga aaatggacat agtgaaagtt
    54361 tttgctaaca atgtgagaaa atatagaaat aaaaaaggtc tatcacaaga agcttttgct
    54421 gaaaaagctg gattgcatag aacttatatt tgtgctattg aaagaaaaaa gagaagtatt
    54481 gctttagata atgtgcagaa aattgctgat gcgcttgaga ttgagactta cttactattt
    54541 atagaaggtg aggagaaaga atgtctatga aaaaattacc aatagaaaag cttatagaaa
    54601 atttaggttt ttcagggtca aagaatcttg tgaatataga tatgcttaca aaattagata
    54661 tatctaaaca tgatgtaaaa actttaaaag ttataaatcc ttatgcaatt tatttagtaa
    54721 atagtaagcc atttatatta tttatagagt cttcttttga agaaaaaaaa ttacaacaaa
    54781 ttagtaagct tatatggaat gctcaaatac caattgcttt tatatgcgat tctaattctg
    54841 ttaaaatatt taatggaaaa gctttggatt taaagtcata tttaattgag gaaatatata
    54901 atcaatctat tgaggatttt tcggaagaat ctgagttttc ttatttgaaa atatctgatc
    54961 cattattttg ggatcaatac actaaacaat ataccaaaac gcatttaaat gattatttgc
    55021 tagataatat tacttcattg acaaataaat taaagaaaaa atataaggtg aaatttgcaa
    55081 cgaagcttgt tctaagatta atatttatta gatatttaat cgatagaggt gtcgatatag
    55141 cttataaaaa ttttaatcat gatattaaag cttcacaaaa agaactgcta aagattacta
    55201 aaaacaaagt tgaattatat gaactgttta aatacttaaa agaaaagttt aatggtaatt
    55261 tatttgagtt aaatgacgaa attaataata cttgtttaac agatgaagtg tttattttac
    55321 tatctgattt tttatcaggt aaaataagta ttgacaatgg acaaatgtct ttattttcaa
    55381 tgtatgactt taatatcata ccagttgaac taattagtaa tatatacgaa attcttttag
    55441 gaaaagaaat tcgtaataaa gataacgcat tctatactcc gaattactta gcagaatata
    55501 ttttagataa aacaacactt gaatttctga aaaataatag gcaatacaaa attctagatc
    55561 cttcttgtgg atcaggagta tttttagtaa atagttttag acgtattatt gatatgaatt
    55621 tgggtgataa acttttttgt gaagatgata aacttttaaa agaactttta ttatctaata
    55681 tttatggaat tgatatcaat gaagatgcta tcgatgttac tattttctcg ttatatctaa
    55741 ctattttaga ttacaaagac cctaagatat tatcagaatt taaactgcct aatttaaaag
    55801 ggtgtaattt aatagcgagt gatttttttg atgataataa attggagagt ttaaagaaaa
    55861 ttaactttga ttttatcatt ggaaatccgc cttggggaag tgtctcagat ggattacatt
    55921 tagattattg caataaaaat ggctataatg atatgcaaca aaacaaagaa atcagtagaa
    55981 gttttatttt tagagcaaaa gattttagct ctagaaatac agtatgttct tttgtagtgc
    56041 attctaaaat actatatact caaaaaaagc catcaaaaaa attccgtgaa tttttgctta
    56101 aaaaaagtca aatatttagt gtagttgaaa tgtcatctgt aagaaaatta gtgtttaaaa
    56161 atgcagacgc tcctgcagca gttatatcat ttaagtataa cgaaagtgaa gaaaatttaa
    56221 ataatagaat catctataca tctttaaaac caaatgtatt ttttaaatta tttaacatta
    56281 ttgtaattga aaaatatgat gttaaatata tttcacaaaa actattattg gagaatgatt
    56341 gggcttggaa aactattgtg tatggattca gtaaagatat agatataatt atgaatatca
    56401 aaaaaaaata tcaaactgta aatgaaatta ttttgaaaaa cagttttgtt catggaacag
    56461 ggatacaaat caatggtaat gaaagccatg atgcgacaca tttaaaagga aagtggtatg
    56521 ttgattcaaa gaaaggaata gattcattct atgttgatat aaataaaggg aaagaactta
    56581 ctcaagataa aatgagaaga cctaaggcta atcagcaaga aatatttatt cctccatatg
    56641 tattattaaa aaagggagtt gacacgaaaa catatagata tagagcagca ttttcaaatg
    56701 atgcatttgt atattcagat gcagttacag gaatatgtgg aaaaaaagat aatttaacta
    56761 cactttattg cttgactggt atgcttaact cttcttttta ctcatactta aatataatgc
    56821 taggtacatc aattggaata gaaagagaac aaggattttc aacggaaatt tttacgtatc
    56881 cagcaataga aagtgatgaa attgctaatc tggtagtaaa aatacaagaa gcgactaaat
    56941 tagaaaaaac aactatgttc ttgaatgaaa aaaatagttg taagtatatc aaacaattag
    57001 ataagttaat tttgaagtct tttaatttaa atgatgataa atttattgac tatgcaataa
    57061 atattcaaat tcctgagctt acaaattcta agtcaactaa catatataga aaaataacta
    57121 aggaagattt aattaattat agtgaatgtt tcaaagaaca gttttcatcg atatatcgta
    57181 gggttgggaa aagtatttca atttcggtat atccaaaaat attaaatcgt tttacagtat
    57241 ttgaactaga agtaacagat gaaaaaacag atagagagat tatggttaaa gcagaagctg
    57301 ataataatat ggagttgttt acgaaaataa ttagatatga ttataatgat gtttttcatc
    57361 aaattagaga tattattcat tttggagaaa attcatttta tatcataaag cctaattgct
    57421 ataaatattg gcatcctgct atcgcagaaa tggatcttgc tgatgttttg gatcagattt
    57481 tatctgatac agggggtgaa gaataatggg aggatttaaa aattcttcac taaactttta
    57541 tttaaagcaa gggctttatg aaataattat agatggatta atagactgtt gtttacttat
    57601 gagcaaatca tgtattgaac aatctagaaa aatattaaat cacgaagaaa agataagaac
    57661 gcatttagtt gaaaattatt tagaaaatga tattgaaaga agaaaaacat ctttatctaa
    57721 acaacatcta agatttgaag tagaagcaca agaaaattat gacaacaaaa atgaatctta
    57781 tgagggtagg gttgatataa aagttatatc taaagacact ttagcggata gaagggctta
    57841 ttatatcatt gaatgtaaaa ggatagatgg taaggaaact ttaaataaaa aatatataac
    57901 cgaaggtgta caacgattta ttactgagaa atattcttcg cattatggca aaaatataat
    57961 gcttggattt atagtaaaag atataaatat ccagagcaat atacaaaaaa ttaattcact
    58021 gaatcagaac atattatata catatataga tacagatatg ttgacagtta gaagtgattc
    58081 tgaaaataat tatgctgttt gtgaaagtaa atataaagta aaatctaaac tactattgtt
    58141 aaatcatatt ttttataact tttcgagtat aataagataa tcttatgaat ataaaatatt
    58201 actatgttaa aattatagtt tggttttgat aatattataa aaataagttt aagaataaaa
    58261 tataaaggaa aaaaggggcg tagcactatt ttttagtgtg acagcccctt taattttaaa
    58321 atcggtaagg aggagtgtat ttgaaaaaaa ttaagtcata tacagggatt ttgaatgtgg
    58381 agaaggttat atatgcaata aatgattttc agcttccatt tccagttact tttacgcaga
    58441 tgacatggtt tgtattaaca ctttttataa ttatattatt tggtaagtta cctccattat
    58501 ttatgataga aggagcattt ttaaagtatc ttggcatacc aatttttata acttagttta
    58561 tgtctcaaaa gacttttgat ggaaagaaac catatggatt tttaaagtca ataatactat
    58621 attcattaag acctaaaata acatacgcag gaaaaaacat taaatttaaa aataaaatta
    58681 ttgatgaaaa tataactata gtaaggagtg aattatatgt tcccgataaa atatatagag
    58741 aacaatcttg tatttaataa ggaaggagaa tgttttgcat attatgaatt aataccatat
    58801 aattattcat tcttataagc tgaacaaaaa tttattgtac atgataattt taggcaatta
    58861 atatcacaaa gtagaaatgg taaaattcat gcacttcaaa tagccactga aagttctata
    58921 agagttacac aagaaaggtt aaagaaaaat attacaggaa aattaaaaga aattgcttat
    58981 gaaaaaatag acgagcaaac agaggcactt gtttctatga ttggcgataa tcaaattgat
    59041 tatcgttttt ttattgggtt taagctttta gttacagaga aagaaatgaa tataaagagt
    59101 ataaaaaagt caatattagc taatctatca gattttatat atgatgttaa taataaattg
    59161 atggatgact ttgtcagtat aaataatgat gaaattatga gatttttaaa aatggaaaag
    59221 ttattagaaa ataaaatctc aagaagattt aaagttagaa ggttagataa aaatgatttt
    59281 ggatatttaa ttgaacataa ttatggaaag aaaggcacag tttttgaaga ttatcaatac
    59341 catttaccta caaagaaact taaaagagaa acattagtaa agaaatacaa tcttataaag
    59401 ccaactagat gtcttataga agagaagcaa agatacttaa aaattataca tgaggattca
    59461 gaaagttttg tagcttattt tactattgaa attattattg gagaaatgaa ttttccatct
    59521 agtgagatat tctattatca gcaacaacag tttgcatttc ctattgatac tagtatgaat
    59581 gtggaaattg taacaaataa aaaggcttta actacagtta gaaataagaa aaaagaatta
    59641 aaagatttag acaatcatgc ttggcagtca gggaatgaaa cagtaacaaa tgtagtagaa
    59701 gcattagagg ctgtaaatga gcttgtaaat aatttaaatc aaacaaaaga atcaatgtat
    59761 aagttaagct atgtaattag ggtatcagca gatagcattg atgaattaaa acgccgttgt
    59821 gatgaagtta aagattttta tgacgattta aatataaaat tagtacgcct aatgggagat
    59881 atgataggat ttcacaatga atttatacct tcaagcaaaa ggtatataaa tgattatatt
    59941 caatatgtaa ctagtgattt tctagcagga ttagggtttg gagcaactca atagcttgga
    60001 gagaacgaag gaatatatat tggatatagt ttagatacag gaagaaatgt ctatcttcaa
    60061 ccatctcttg caagtcaagg agtaaaagaa tctgtaacta atgcgttggt agcagcattc
    60121 tttggatttt taggaggtgg gaaatcattt gctaataact tacttgttta ctattcagta
    60181 ttgtttggag ggcaagctgt tttggtggat ccaaaagctg aacgtggcaa atggaaagaa
    60241 aatttaccag atatatatca tgaagtaaat attgttaatt taacaagtga tatagaaaat
    60301 aagggaatgc tagatcctta tgtaattatg aaagaagtaa aagatagtgg aagtctagct
    60361 attgatatat taacttttct tacaggaata agtagtcatg atggagagca gtttcctata
    60421 cttagaaaat caatcataaa tgttactcaa gacaaatgca gaggactttt gaaggtaata
    60481 gatgaattaa ggaaagataa ttctcaaata tcaaataata ttgcagatca tattgaaagt
    60541 tttacagatt atgattttgc acaattactt ttctcagatg gaaatattaa aggctcaatt
    60601 aatctagaaa aacaaatgaa tataatacaa gttgcagatc ttgttttacc gaataaagat
    60661 actttatttg aagaatatac aacaatggaa agtctttcag tagctatgtt gatagtaatt
    60721 agtacttttg cattagattt tatccataca gatagaagta cttttaaaat agtagattta
    60781 gatgaagctt ggacatttct taatgtagca caaggaaaaa ctttatctaa taaattagtt
    60841 agagcaggat gtgctatgaa tgcaggagtg tattttgtaa ctcaaaatgc aggtgatgta
    60901 tcagatgaaa atttaaaaaa caatattgga ttaaaatttg cattcagaag cacagatatc
    60961 aatgaaatta agagaatact tgaatttttt ggagttgata aggaagatga gaataatcaa
    61021 aaaaggttaa gagagttaga gaatggacag tgtttaatac aagatttata tggacgagtt
    61081 ggggtaatac aaatacatct agtttttcaa gaactcctta ctgcatttga tacaagacca
    61141 cctataagaa aagaggtgga ttaatgaaat cgaaagtatt tagaaattta agctggataa
    61201 ctattttaat agtagtactt ttactatttt ttatttatat aaatttatag atttagagaa
    61261 acaaatagat acattagata agaaaagaaa aaaactcata gatatgagat tagaagatat
    61321 aattgataaa gaatcatatg aagaaaagta tgatgattta acagttgaaa taaagaaact
    61381 tagtaaagag aaaaaaactc ttaaagcatc attaataaat gaaaagagta taaaagcaag
    61441 acttagagaa tttagaaaga tacttgaaag aaatgaattg ttagaaaaat ttgatagata
    61501 tgtatttgca agtatagtag ataaggttat agttggagtt attaatgaag atggtatagt
    61561 tgatccttat aaaataactt ttgtttataa aactagcttt gatgataaac aagatggaca
    61621 taaatttata aataagagtc cgttagaaac gtattcaaaa gataacaacg ataataaaaa
    61681 gaagtgttca tatactaata atgagacatt gcgagactgt agttaaactt attagagaat
    61741 aacaaggttt cagactttta tattgtgtct taaaagtaga tttgccacct atttgccacc
    61801 ataattattt ttgggtggca aatttattct acaatgattt caaaaatatt taccgtctgg
    61861 tttctcatgt tgttagttac atgtaaatat gtatccatag ttgttgaagt tttagcatgt
    61921 ccgagtatat gctggatatc ttttatatta gtaccatttt ctaataacat agtatcaggg
    61981 tttttaaaat aaagtgtgta ttcttctaaa gtagtgataa ttaaaatatc aaatatcact
    62041 atacaaagga aagtgcacgc tttttatgtt taacaaaaac gaaatattaa aaaacttatt
    62101 gaagaatatg atgtcaaaac aactacagat attcaagata tgctaaaaga tttatttaca
    62161 aatacaattc atcaaatatt tacattgtcg aattttagcg gtttaaacat aatatattga
    62221 ctgatataat aaaatcatag aatattttag ggggaaatag attatgttta agaaaaagtt
    62281 aatagctgtt gcaatgagta taactatgat tagtgtaggg agcttttcgt atgctcattc
    62341 aggaagaact gattcatcag gaggtcatcg tgataataaa aataaatctg gattaggaag
    62401 ttatcactat cattgtggtg gttatccagc tcatttacat aataatggtg gttgtcctta
    62461 tactggagga ggaagcagtt ctggaacaac aacttcggtt aataatgaag aaaagcaaaa
    62521 gaggtctgtt ggagaaaaag gatataatca agggtatgaa gatgggtata aaggaaatta
    62581 tagttcatca aattatagtg gagattatag tgatacatat gaatcaaagt actcagaagg
    62641 atatgaaaaa ggtaaggcta aattagaaga ggaagaaaag gtggctaaag agactggata
    62701 taatttaggg cttacaggtg ctaaatctaa taatacatat gaaaaagaag ttttaaaaaa
    62761 tgcttatgat accggatatt caactggata caatgaatat aagactaaaa agatagaaga
    62821 atataaagct aaagggatag aggatagcaa taaagataag gaaaaaatga catttgaaga
    62881 aaacatagat tctgaattta tagatgctta taataatgct tatgacgaaa tacaagaaca
    62941 attaaaaaat gattacacta ctcaaggatt tgagagtgct atcaaaggag aaagatttga
    63001 cacatcaact ataggtaatg ttaaatatgc taattggttt aaagaaggat atgataatgg
    63061 taaggttaag ttacctaaag caaaagaaag tgtatataat caaggttaca atgaagaaga
    63121 ttttagtata ccagatgaaa tgaagtctat tgaaactaag ttaaaaggtg tatatgatga
    63181 aggtttagaa aaaagagaag aagagaaaag tagaaatgct acttatgggg ttggagctgg
    63241 aacagcagct gtagttgctg gagtagtata taagaagaaa aaacgtaaaa agatatagat
    63301 gctagatata ccaatgatga caagtgtata acaaatataa ttttaagtat aaatatttaa
    63361 aatatagaag ggaaggttat atctatggga tttaacttta ggaaaagcat aaatctagga
    63421 ggaggactca aattaaattt aggtaagaag agtgtaggta taagtgctgg tgttaaaggt
    63481 gctagagtgt cagttaattc aaaaggaaga aaatcagcta cattgagtat acctggaact
    63541 ggaatatcat atacaaaaac tagtacaaag aaacgtaaac ctaaataaat atttgatata
    63601 ctaagaaata gactgttaca aatagtctat tttttagtat atagatttaa aaagtgacaa
    63661 aattttgaaa tataaactaa tttcataaag gaaaatatta ttttatgtag aattataata
    63721 tttaagtaat attataaaat ttataggagg atttcattat gaaattaagc aaaatactat
    63781 tggcaatagg gatgtctgtt tcattattga ttgctagttg tccaacatca aacgctctta
    63841 gttctattaa ttcaataaaa ggtacaaata agtatgaaac agcaggttta atagcagata
    63901 aacaaaatta tgatattgca atacttatta attctgaaaa tggattatct gatggattgt
    63961 cagcaagtgg attgtcagga gctaaaaatg ccccaatatt gttaactaag aaagatacaa
    64021 tcccttcaga aacattaaaa agattagaaa aggtaaaaga agtatatcta attggaggaa
    64081 aaaattcgat aggagcatca gttcagaaaa tattaagtga taaaaaaata agcataaata
    64141 gaataagtgg aactgataga atagatacaa gtcataaagt tgcaaaagaa ataggaagag
    64201 taagtacggt taaaaaagta atattaacta atgcttttaa aggcgaacca gatgctatga
    64261 gtgttgcttc tatagcagtt agagataaat ctccaatagt attaactgat ggaaatacta
    64321 caagttttgc tacagatgga ttagaaactt atgcaattgg tggaaaagtc agtatgagtg
    64381 ataagttaat aaatgaaact aaagcaacaa gaataggtgg agtagataga tacgatacaa
    64441 ataaacaaat aataaataaa ttttataatg gctcaaaaga attttacata gcaagtggga
    64501 ctgatttagt ttattcttta gttggttcta caattgcaca aaaaacacct atagtgttag
    64561 ttggaaatgg aagtaataag agtatattaa aaaatgcaag taaaataact gctattggaa
    64621 atattgatga tgttgttata aaacaatgtt taaatataac taataatgtt ggggattcaa
    64681 atacaggtat tgtaaaagat actaattcaa ataatacgaa caaaccaagt aatgagccta
    64741 gctctaataa tcctggatta actgataaaa gtacagtata tgtaactcct aatggaaaat
    64801 catatcatct aacaaaaaat tgttctacac taaaaagaag taaaacaata aataaagtaa
    64861 cattaaaaca agctaagtca caaggtaaaa tagatccttg taatgtttgt gtaaaataat
    64921 gtattagcca aatatatatt aaaaaagaca attaattaag attgtctttt ttattgaaga
    64981 aatataaatt tatattatgt attattaaaa aaaattatta attataaaaa ataataataa
    65041 agacgataag tattaaaatt ttatgtttcc aatatttatg atataattaa tatggcaagg
    65101 aataaatatt tgaaaaagct atgagtggtg tttccatgga agtttcttca ctttcttatg
    65161 agaggaggtg aaaactatgg aaaatctaat gatgagtatt ataactggtg ttatagccag
    65221 ttacatttac gataaattaa agagccactc tgagcgacca actaagagtg gctgggaact
    65281 taatataaag ttccagaaaa gtaaatcttc aaaataattt gttgaaggaa acatcactca
    65341 aagttaagta aaatatgttt ccttgctttt attatatcac aaattaaaaa tattaacaca
    65401 aaattttgtg aatatatact tattattgtt ctaaaaaaat atgtaaataa ttgatttgat
    65461 tgcatggaat tattgatgta atatttaagt taaatataca caatctcaat taaagaagat
    65521 aagtactata aattcatatc aaaaaaatac ataaactttt aagttataat tttataaaaa
    65581 gtcttttagt atcattattt caagaggaat tatcatatga aaaaataact tcattagaaa
    65641 agtggataaa aaactggtaa gaagatgact aaagattaca tatactatta cttaaattaa
    65701 aaatttaata taatttataa tgtatacaat ttattataaa aaatttaatt ttaattttct
    65761 atttttgata ctataatata taatcttgat aatttaatta aaaatctaga ttttacatac
    65821 caaactggtt tcttatttcg ctatctttac ttatgaactc atatattcct ataaaggtta
    65881 ttttagaaaa agttggttat ttaaacatta ataccacaat ttctatagat tgtttggtga
    65941 ataatctata attatattat ggactaaaaa atccaatgag ctaatttatt gtttttttat
    66001 atttgagaga ttacaactta ttagtttgta tatctctttt tttaataaaa tcaataatat
    66061 ataaaactat tggcatattt aatgacaatt caaatattgt atataaccat aatgaaagat
    66121 atataaataa aattttaaat atacttaaaa atatattaat ataatgtaca taaaaaatat
    66181 cataaatata tgataagata aatacaatag caacatttta ttaatttttt gggtttttat
    66241 atatttaggt actggggtga tatagttgaa ccaagagata ttttttaaaa taatgaatga
    66301 aatattggaa aatattgatg aaggggtaca ttttgttaat aaagacggga aaactataat
    66361 ctacaataat tctgtacaaa aaatggaaaa aatgaacaga cacgatattt taaccaattc
    66421 attttttgat atagtcaaca aaatgaaaat aaacaggagt acactattag aagttttgga
    66481 aaaaagggaa gttatcaaag acaatattca aaaatatctg gataaaaatg gaagagagat
    66541 aacagcaatt aatactacaa taccaattga tattaaaggc gagtttgtag gggcacttga
    66601 gatatcaaag aatatgacaa cgatagaaaa tttactaaac agaaattata aaaaaaattt
    66661 agtcaataaa gttagtatta gacaaaaaaa gggttatgaa tttgatgata ttttagggga
    66721 aagtaatttg attaaagaag caatagctaa atctaagaaa gcttgcaagt ctgatgcttc
    66781 agtatttata tacggtgaaa ctggaacggg taaagagtta tttagccagt ccattcacta
    66841 tggaagtaat aggaaaaact atccatttat agcacaaaat tgtgcagctt tgccggaatc
    66901 actattcgaa ggtattcttt ttggaactag caagggagga tttacaggag caatagatag
    66961 gccaggctta tttgaacaag ctaacaaagg gacattgtta ttggatgaga taaattccat
    67021 gcctattatg ttacaggcta aactattaag ggttttacaa gaaggttatg taagaagggt
    67081 tggaggaact aaggatatac ctatagatgt aagaattatt gcaacgacaa atgaaagtcc
    67141 aaaggtaatt ttaaacgagc ataaaatgcg aaaagattta tattataggc ttaacataat
    67201 tcatataaaa attcctcctc ttagagatag aaaagaggac atacctctat tgtgcaaaaa
    67261 atttatttca aagtataata aaaagttaaa taaaaaagta gtaggaattt cagatgaagc
    67321 tattaaaatt ttaaaaaatt acgattggca aggtaacata agagagctag aaaacataat
    67381 ttattgtact atgagtatga tggaagatga ggtacaaata gaaacaagta tgattaatct
    67441 aaacgactat tacaatctta aagagaataa agagagtaac aattattctt taaacgattt
    67501 ggaggacaaa acacttagta agattatcag tgagatagaa gaaaagtata tatatgaatc
    67561 attagaaaag gcatcttaca atataactaa agctgcatca attttaggta tgaataggca
    67621 aaatttacag tataaaataa aaaaatataa tatcaaaata ttataaataa gcaagataaa
    67681 aaaacaaaat caaagtaaaa taaaaaagca aaatagagga gcaaaattat tataaaagag
    67741 caaaatattt tgctcttttt tttatttctc ataagaaata ttatttttta tttatgaaaa
    67801 tacataataa aataattata gtttcaacgt ttcaataaat atttacttta attttaaagt
    67861 tggcacgatt tatgctttaa ctaattattg agaatatata aatttttagg agggtgtata
    67921 tatgagaaaa gtaagagtag gaatatgggg atttggagct atgggaatag gtatggctaa
    67981 tatgattcta aagaaagaag gtatagaaat agtatctgtt tgtagtagaa gtacttcagg
    68041 aaaaagtatg tataatgttt taggaattga aagaggagaa agaccagaag ttattatcaa
    68101 taaaaattat gaagaagttt ttagagaaaa aagtgtagat gttgttttgt tagcaactga
    68161 ttcatttact aaaaaggctt ttgataaaat aattttctta ttaaatagaa aaataaatgt
    68221 tatatcaaca gcagaacaaa tggcatatcc acaagctgat gatgcagatt tagctaaaaa
    68281 aatggatgaa gttgcaaagg aaaatggagt aagtatactt ggaacaggaa taaatccagg
    68341 atttgtatta gatttactag tattggcgct ttcaggcact tgtgaagaag ttactagtat
    68401 aaaagctaag agagtaaatg atttatctcc atttggaaag tctgttatgg aggaacaagg
    68461 tgttggagta acaagggaag aatttataaa aggtgtagaa gataagacta tagcaggtca
    68521 tgtaggtttt gtagaatcaa taaatatgat agctgatgga ttaggttgga aattagataa
    68581 gatagaacaa acaaaagagc caataatgac tatagtagat agaaaatcta agtacggaga
    68641 ggcattggct ggaaatgttg ctggttgtag acaatgtgga tatggatatg taaatggaga
    68701 agttttaatt gaaatggagc atccacaaca gataatacca gaagcagaag gtattaaaac
    68761 aggagactat gtatcaataa aaggtatacc aaacattgat ttacaaataa atcctgaaat
    68821 acctggagga gtaggtactt atgcaatgat agtaaactct attccattaa taataaatgc
    68881 tagaccaggt cttaaaacta tgttggatat accagtacct agagcaataa tgggagatat
    68941 aagaaatcag atagaagttg aattggaaga agaatcaaag gctaattagt aagataacag
    69001 ctaactaatt agtaagatag caactagcta attagtaaga taacagttag ctaattggta
    69061 aaataatgtt taatttaaaa taacagtaaa ttaattagta aggcaatagt caattaataa
    69121 ggggatgaaa aaatggatgc taaaattaat gattgggtta ttatacacaa tatagtattg
    69181 actccagaag aaagagctcc acaagttcca gaggatacta agaaagtatc cttagaaatg
    69241 tgggttaaag gttttataca aagtgatgct tctataggcg acttagtaga agttaaaaca
    69301 attacaggca gacttgtaaa aggtaattta cttaaaataa atccatatta tactcatgat
    69361 tatggtaaat gtataccaga gttactccaa ataggaatcc aagctaaaga aatattattt
    69421 ggaggtgtat ataatgaata attcaacatc aatgaaagat atgagttatc aagctgttat
    69481 gggaagaaat aacgaaataa tgaaaaatgc aatcggattg gattattctt attttgaaca
    69541 agagggaata gggtttgatt atgagaaaat gatgagtgaa acaggatata cattacaaga
    69601 tattgaagca attcaatcac agtatgctgt tggaaatact cctttaatag agcttaaaaa
    69661 tttgactaaa ttagctagaa aatgtgctaa agaaggtaaa ggagctagaa tatttgtaaa
    69721 agatgaagca atgaatgcat ctggtagttt taaagcaaga agagcagcta ctgcagtata
    69781 tcatgccaaa caaatgggat ataaaggtgt aatagcagct actagtggta actatggtgc
    69841 agctgtagca tcacaagcgg caatgcaggg attaaaatgt ataatagttc aagaatgtta
    69901 tgattctaat ggtgtaggtc aacctgaaat tatagaaaaa gcacgaaaat gtgaggcata
    69961 tggagcagaa gttgttcagt taactgttgg accagagtta ttttatacgt tcttagtttt
    70021 attagaagaa acaggctatt ttaacgcatc attatattca ccatttggaa ttgcaggtgt
    70081 agaaacttta ggttatgagt tagctatcca atttagagaa aagtataaaa aagaccctga
    70141 tatagttgtt tgtacaaatg caggtggtgg taatcttact ggaactgcaa gaggattgat
    70201 aaaagctggt tctattaata ctaaagtagt aggagcaagt gtagatttaa aaggattaca
    70261 catggctagt gataatcaat ttaataaaaa atcatttaca acaggacata caggttttgg
    70321 gataccatac tgtacatggc ctgataggtc agatgtacct aggtctgcag ctagaccact
    70381 tagatatatg gatagatatg tattagtaaa acaaggagaa gttttttata caactgaatt
    70441 attggcacag ctagaaggta tagaaagagg tccagcagga aatacatctt tagcagcagc
    70501 attctcttta gctcaagagt tagatgagga taaagttata gtggtacaag aaacagaata
    70561 tacaggcgca ggtaaacata tatgtccaca gcttactttt gcaagagaaa atggaataga
    70621 tataaaattt ggaaatccaa gagaagaaat tgcaggagta aacttaatat taccagaaag
    70681 accagaatta ttgaaatgtg ttgatattga tatgaataaa ataagaaagt catttataaa
    70741 aaattgtata tctaataatc acattgataa tattgataag ctaagtaatc gagatataga
    70801 atttttaatg gaagaagtaa aaagttcaag agattttgtt gttgatgtat taaataattt
    70861 atagtaatta ttgtttttta atttaatata aaataaaaat tcagaaaatt cgattaaatc
    70921 aatacgaatg gaggaatgtt catgaaaaaa agagaggatg attttgaagt tagaagaaaa
    70981 catcttcaag aactgagtga tgatgagtta aaagaaaggt tttggagttt agctacccag
    71041 atagtagaac caatgataga acttggtaaa aagaatacaa caccatcaat agaaaggtct
    71101 gtcttgttga gaatgggatt ttcttctctt gaagtaaaac ctattttaga aggggttatg
    71161 gaaagaggtc ttataggtaa aggagcaggg catgtagttt ataaattggc taaatctaaa
    71221 aatataacgg ttagagaagc aggtttgtta ttagttaagg gtgaatattg ggatgaagtt
    71281 acatgtttat ttagagaagg ggtagaatca tgttaaagga aaataaaaaa ttggatatag
    71341 actatatatt aaaagatttg gataaatata aaccaaaacg aagaggttgg gtttggagag
    71401 aacacttgga aaatcttgaa atgggacctt ttaaatataa agactgtaca aaacctttaa
    71461 agaagagtgt agggctacca tcatctaagt atttcaataa tatagaccct caaccaagtc
    71521 cagttattac tactgaaata gcttctggta gatttgagga tgatataaga agaatgagaa
    71581 tggcagctca tcatggagct gaccatctaa tggttatcag aactgctgga caatcacatt
    71641 ttgatgggct tatagaagga actccacaag gtataggtgg agttccaata acaagaaaac
    71701 aagtaagagc tcaaaggaag gctcttgatt ttatagaaga agaagttggt agacctatta
    71761 attaccattc atatgtaagt ggtgttgctg gtcctgaagt agcagtaatg tttgctgagg
    71821 aaggagtcaa tggagcacat caagacccac aatataatgt tctgtatagg aatataaaca
    71881 tggtaaggtc ttttgtagat gcttgtgagg caaagaaaat aatggctttt gccaatatag
    71941 ctcaaattga tggagcacat aatgctaatg ctactgctag agaagcatgg aaggtaatgc
    72001 ctgaacttat ggttcaacac gctttaaact ctatattttc agaaaaaata ggtatagata
    72061 aaagtaatat atgcttatca acagttccac caacagcacc tccagcacca tgtttaaaaa
    72121 tagacttacc ttacgctgtt gcacttagag agttatttag tgattataag atgagagctc
    72181 aaatgaatac taaatatatg gaatcatcaa ctagagaagc aacagttact catgtattaa
    72241 acttattaac atcagtatta actagagctg acatacaatc aactataaca cctgatgaag
    72301 gtagaaatgt accttggcat atatacaata tagaagcatg tgatacagca aagcaagctt
    72361 tagttggtat ggatgggctt atggatatga tagaacttaa agatgtgggt gaattaagag
    72421 acaaagcaag agaacttaaa gaaagagctg tattatatat ggaagaaata tctgaagttg
    72481 gtggatattt tgaatctgtg gaacaaggat tttttgttga ttctggaaat tatccagaaa
    72541 gaaatggtga tggaatatct agaaaaataa aaggtggagt tggtgaaggt actgtttatg
    72601 aaagagaaga agattattta gcacctgtaa ctgctcactt tggatacaat aatgtagctc
    72661 aatatgatga aaatgctata gataatccat caatgttaat agatggatgt acatttgaaa
    72721 atccagacaa aataatatat attgatgagc ttgacgattt tgataatgta gaaaatagac
    72781 taaaagaatc atatgagtac agaaatggaa ctaaaattaa gcctgaaatg gaatggtgtg
    72841 cagatggaat tgtaatgata acaatgatgc ttcctactga taaaagaaca gcagagtttg
    72901 cagctttgga atttgtcaaa aaaatgaact tacaagaaat tgaggtcata agtagagaag
    72961 ttatgcatga atctgaaggg actagaatag aagtgaaagg aagagttccg tttgatatag
    73021 atttaaacaa tttagtaata ccagaagaac ctaaggtact aactgatgaa gaaataagag
    73081 cagatataga agaaaaacct atgaaaatag tttcagctac ggttggagaa gatgaacatt
    73141 cagttggttt aagagaaata atagatataa aacatggagg tattgaaaaa tatggcatag
    73201 aatgccacta tctagggact tctgtacctg tagaaaaatt ggtagatgca gcgattgaac
    73261 tgaatgcaga tgcaatactt gcatctacaa taataagtca tgatgatatt cactataaaa
    73321 acatgaaaaa attacacgat tattgtgtag aaaaaggtat aagagataaa gtaatgattg
    73381 cgtgtggagg aacacaagta acacctgaaa tagctgttga acaaggcata gatgctggat
    73441 ttggaagaaa cagtaaaggc atacatgtag ccactttctt agttgaaaaa agaagagaaa
    73501 tgagtaataa ataatggaaa atagcaaggt ttctttaaaa atagatgtgt tggtagctga
    73561 aattggaagt actactacag tggtaaatgc tttccacgat attaatacta acaatcctat
    73621 atttttgggt caaggtcaag ctccaacaac agtgtttgaa ggtggcgatg taagaaatgg
    73681 cttatcaggt gctattaaag atttagctaa taaattatct gtagatgata tagagtataa
    73741 tgatatgttt gcaacttcta gtgcagctgg tggattaaaa atgactgttc atggattagt
    73801 ctatgatatg acagtaaaag cagctaaaga agcagcttta ggggctggag ctgttattcg
    73861 tcaaataaca tcaggtagaa ttaaaagaac tgatttaaat aaaataaaag aaataaaccc
    73921 aaacataatt ttaatagctg gtggagtcga ttatggagaa agagatacag ctatttataa
    73981 tgcagaaatg atagcttcta tgaatctagg cataccagtt atatatgctg gtaatgttga
    74041 aaatcaagag gaaataaggt taatatttga agatactaat tataagcttt atataactga
    74101 aaatgtatac cctaaaatag atttattgaa tatagaacct acaagaagaa tcattcaaag
    74161 tgtatttgaa gaacacataa ctacagcacc aggaatgaaa tacattaaag aaatggttaa
    74221 tgaaaatatt actccaaccc caggagctgt aatggaagct tctaaacttt tatataaaaa
    74281 tattggagat ttattaactc tggatgtagg tggagcaact actgatgtac attctgttac
    74341 agatggaagt gactatatta ataaaatttt ggttaatcct gaacctactg caaagagaag
    74401 tgttgagggg gatttaggtg tatatgtaaa tatgaagaat atagtagaag ttataggtaa
    74461 agaaaactta caaagtgaac tatctataga tattgatgca gtaatagaga attatcctcc
    74521 aataccaaaa tcaaaagaag aaatattatt tgttgagagg ttgacaaaag aagctgttgt
    74581 taaagctatg ctaagacatt caggaaaaat aagaaatatc tatggaacaa ctggaaaagt
    74641 caaaattgca gaagggaaag atttaacaga agtaagatat atagttggta cagggggagc
    74701 acttactagg ctccctagta gaattgaaat attagataat atgctcaaat acaataaaaa
    74761 taatgaatta ctatttccaa aggaaaaaac aaagatatta atagataatg actatattat
    74821 ggcatctatg ggtgttttat ctaaaaaata tgaagaagca tctcttaagc tcctgttaaa
    74881 aagtttgaat tttgaggagg aaagattatg tatcctaggt tagaaataga tatagaaaag
    74941 ttaaagcata atgcaaaatt aatttcgcag atgtgtcatg aaagaaatat taagatatct
    75001 tttgttacta aatcattttg tgcacaaaaa gaaatagtag aagaaatatg tagtgaagga
    75061 atagaccata tagcagattc aagaatacaa aacttaaaaa atttacaaga tataaatcta
    75121 cctaagatat tgattagaat cccaatgtta agtgaattag aagaagttat caattattgc
    75181 gatattagtt ttaactcaga attaggaaca ataaagaaat taaatgaatt atgtgaaagt
    75241 aaaaatatta ttcataagat agttcttatg tttgacttag gcgatttacg agaaggatac
    75301 ttttatgaag aagacttttt tagtaatgta agagagatag taagattaaa aaatattgaa
    75361 ataattggta tagctacaaa cttaacctgt tatggagcta ttataccatc tagggaaaat
    75421 ataggcagac tggtaagtat agcaaaaaga atggaagaaa aatttggaat aaatctagaa
    75481 atagtatctg gaggtaattc aagttctatt catctgttga taaataataa tatgccagaa
    75541 ggtattacta atttgagaat aggcgagtcc attctacttg gtagagaaac ggcatacggt
    75601 gaaaatataa atggaacata tcaagatgca tttaaattaa tatgccaagt agttgaatgt
    75661 aaagaaaaac catcagttcc tattggagaa ataggagttg atgcctttag aaataaacct
    75721 gtttatgaag ataagggaat cttaaaaagg gcaatcatag ctataggtaa acaagatata
    75781 aatattgact ctttaattcc aatagacact gatataaaaa tattaggggc aagttcagac
    75841 cacatgatac tagatgtaag taacacaaaa tatgattata aattaggtga caatttagaa
    75901 tttttattaa cttatggggg tatcatgtca tctagtacga gcaaatatgt ttcaaaaaaa
    75961 attatagtgt agtgtttaaa taattaggag gaaactattt tatgaaagag cgagaatgta
    76021 gaaaagcaag tctgtttgat gcaatgatac caattacttg tttgatatta tttttaagtc
    76081 taggagtatt agtgtatggt tcatcacctc atgtaccact aataggagca gcagcagtag
    76141 caggacttgt ggctgtatat agacttggat ttaaatggaa agagttagaa ttaagtatgt
    76201 ttaatagtat aaagatggca atgcaagcaa tcttaatcat aattataata ggcgtactta
    76261 taggaacttg gatagtaagt ggagtagttc catgtatgat ttactgggga ctaaaaattt
    76321 tatcaccaaa tattttttta gtagcatcaa cattagtctg tgcaatagta tctcttgcga
    76381 caggttcatc ttggagcaca atgggtacag taggagtagc tcttttaggc attggtcaaa
    76441 gtttaggtat gccaattgga ttaatcgtag gttctataat atctggagct tactttggag
    76501 ataaactatc acctttatct gaaacgacta acttagctcc agcaatggca ggaacagatt
    76561 tgtttacaca tataaaatat atgctatatt cgactatacc atcattatta atttgtttag
    76621 taatttatgg tgtaattgga atgaagtatt caggtcaagc actagatata aaacaaatag
    76681 aattaattag gtctacatta gattctacat ttaatacttt atcaccagta ttattattag
    76741 ctccagcaat agtaattgga ttggttgtat ttaaagttcc tgctatacca gggcttatag
    76801 taggtgctgt attgggagta ttgtttgcag tagtttttca aggagaatct atgaatacga
    76861 tattagatgc agcacaaaat ggatatgttt cgtcaacaca aatacaggag gtagatgctt
    76921 tattatctaa aggtgggatt atgaatatga tgtccactgt atccttaaca atatgcgctt
    76981 tatctcttgg aggtatttta gaaaaaacag gtatgcttga agtagtagca tcttctttac
    77041 taagattagc aaagggtgta tttggaacag tattatgtac tatggtaact tgtacaatta
    77101 ccaatataat agcaggtgaa caatatctat ctatagttat accaggaaga atgtataata
    77161 aggaatataa aaagagaggt atacatccta agatgttgtc gagagcttta gaagatagtg
    77221 gaactttaac ctctccatta gtaccatgga atacatgcgg ggcgtatata acagcaacat
    77281 taggtgtatc tgcactaaca tatggtccat acgctttatt aaatattata aatccaatag
    77341 tatctttagt attaattgca tgtaagttta aaatagcaag aatagaagat gaacctgaaa
    77401 cttgtttaaa ttttgatgtt tgataataga taacttatgt aagaacgtag gaactagggg
    77461 ggtagcctgt ggggaattag taagacatat tttagtgtgc gaaattctat aaatcagtaa
    77521 tcttgtgact ttagccatgg gaggttcaga ttagtaaatt tatagtttta tattagtcta
    77581 tattttgatc ttttaattgt ttgtataaat tttttataga aaaagatttc ttttagactt
    77641 gcctaaaaat taggcaagtc ttttaagtat gttctgatta taagagcact gtgtgacaag
    77701 aatgatgaga ttatttttgc tatactttcg atataagaaa tggaaggagg ttatgtttta
    77761 tattcatatg aaataattag ttacacagta aattttcgta taatttggta taaaaagatt
    77821 agaaatgaaa ataaagtaat ggaggaataa aatgactaga atatccaata taacaatagc
    77881 tgaacaatct gagtactgtt ttttggcaat acgaaaaaca attgacttta tggtagagtt
    77941 ttcagagttt tcaaaacaaa gttttgaaaa aatttctaaa tatctggagg agagaggaat
    78001 tttatcttca ggagcaccga ttgtatgttt tcataacatg gatttagcaa aattggatgt
    78061 tgaagtaggg tttcctgtag ccacttatat agatgggaaa aatgagattc tacaaaggat
    78121 tgttcctgca cagaaaataa taactgcaat tgatttagga ccttatgaat tacaagaccc
    78181 tactttagaa gacttatttt catgggcaaa tagcaatgga tataaacttc atggcgatat
    78241 atattaccag tatttaaatg atatcaatcg tccagctagt gaatatctta cgaaaatgat
    78301 gttacccatt atatagaaag ttaaagatta tcgtttgtta gttgataatt agaagaacat
    78361 ttactgctac tacataaatt ttatcctaaa taatatcaag gtgatttaat ttatgtattc
    78421 taatgtaacc ccaatatatt gttaaggtct acttaagatg ctcaaaaggc tatgcttaat
    78481 ttattgttat ataatttgta gagtggtata atttagaggt aatattatat agatatatag
    78541 ggggaaaata tgaaaatata tgatatatta acacgttttt atattcaaga tatagaaaaa
    78601 gccatacctt tttatgaaaa tcttttaaaa gaaaaatgtt ctttgcgttt ttcctataaa
    78661 gaagttgggt tggaattagc gcaaatagga aatgttttac tattatctgg ttctgatgat
    78721 gctcttaaac catttataga aacaaaatct acttttatgg ttgattctgt tgatgaatgg
    78781 agaagttatc tattggataa tggagcagtt gtagtaagag ataagaaaaa agttcctaca
    78841 ggatataata tgacattgag acatccagat ggtacaatta tagaatatgt tcaacataca
    78901 aagcaggatt agttaaaaac agattttact actgagcaac taattagaat ctattcttag
    78961 acgtacaatt tattattttt ggtattaaca gattataagt caaattataa tatttcaaaa
    79021 tagaatagaa atttatttac ataaaagaga gtgtttaaaa atgaactttt tagttcatga
    79081 agcactcttt tttgtatgaa atcaaataca tcaatatata aaataaactg atgaagagct
    79141 taaattaaaa taaaaagatt cataacagga ccccattaaa ctttaagata gggtaagttt
    79201 gtaatcatat taaataattg taaaaagctg tttttagtcg tataatataa atatttatca
    79261 tttaattaag gaatataaaa ggaatctaat aagaagaaaa taataaataa ctttttagat
    79321 ttactaaatg aaaagttatt gaaaattaaa ggattagagt ctttaatcag aaagtaaaaa
    79381 gtaatatatt aaatttatga attgaaaact taaacaacaa atttgtttat aaaatagcaa
    79441 gattcattaa atataactaa gtaataattg atataatgtt gcatggataa aaggagggaa
    79501 gctgcaatgt cttacaaagt aattaatgtc ataactgcta ttgactatat agaggagcat
    79561 ttatcagaaa agctggattt agatatagtt gctaatgctg ttcattactc aaaatatcac
    79621 ctgcatagaa ctttcacaac ttctgttggt ctaacaatgc atgattacat aaagcggaga
    79681 aagttgacag aagcagcaaa attattggta ttttcaaaga aaccaattat tgaaattgca
    79741 ttgatagctg gatatgaaag tcaacaggca ttcacttcta tatttaaagc tatgtataaa
    79801 aaatctccaa ataaatatag gaaagaacaa gaattttatc ctttgcagct aagatttgtt
    79861 ttgaaaaaag ataacctatt ttcaaagaat gtactagagt tggaaaaaga aattaaactt
    79921 gcaagtatgt ctgacatacc attatggatg aatttagtga gattagtcat agatggattt
    79981 ccaaatttgc aagaggaaga atatatatat caattagaac agtatatttt agaagaaaga
    80041 gctttaatat taaaacttaa taatgtcgct attgcaaata tggtgtttaa tagagaaact
    80101 agaagtattg atttttttgg aatacatcca cagtatcgta attcagacat tgcacaagtg
    80161 tttttgaaga aagttattga agatttcttg atagatacag atatttcaat tactaccttt
    80221 cgagagggtg acaaagctga tacaggacat agagatatga taaagaagtt gggctttgca
    80281 gaagcagaat tgcttgtgga atttggatat cctactcaaa aatttattct tccttgtgta
    80341 gaagaaagag ataatagaca aaattaattg tagattaaat gaaaagttta ccacatattt
    80401 tttgtttgaa ttattttata tataagagca tttctgcttt taatgtattt tgcttgtaag
    80461 tgtacttatg gtaataaata tagaaagatt tagtttttta aaaaaggaac tttaaagcta
    80521 aaaagctaac atttaagtta aatagcaaga atgattaaaa actccaaaac acaattaagt
    80581 ataatgattc agtgtaagta cttaattaac aaaggaggat ttaaatgtct gaaaataaac
    80641 aagtagtaaa ttgcgatatt attgcatcta attctaaaca taatatgtgt gaatatgatg
    80701 cagagttatt aacttttttt ccagatgaga ttgcacatct aatagagata aataacaagc
    80761 tagacaatgc ttttaagaaa gctgaaaatc ttgttgacaa gcttgataag gattatatgg
    80821 acgctaaaat gtatatggta aaaaatcgtg gtgaaataga cccacatgaa atgtttcaaa
    80881 atgaacaagg actaaaacaa atagataact atggggcttt tatggtaaaa gttcgagata
    80941 agattaataa aatcaaagat tctccatact ttgctagaat agattttagg ctgaaagata
    81001 tggatgatga atctaagtat tatattggta gatttgcatt tgattatgaa gatgagctta
    81061 taatacttga ctggcgttct ccaattgcca gtatgtttta tgattatgaa atcggaaaag
    81121 ctggatatga tgctccaata ggatgggtgg atggagaaat aacaagaaaa cgacaattta
    81181 aaattaaaaa tggaaaatta gaatatgcac tagaaagttc cattaatata caagatgata
    81241 ttcttcaaaa agaacttagt cacacttcag atgaaaaaat gaagtcaatc atttcaacaa
    81301 tacaaaagga acaaaatcaa attattagaa atgataaagc tgatacactg attattcaag
    81361 gggtagctgg ttctgggaaa acatctatag cattacacag aattgctttt cttctttatc
    81421 gatttaaaga taaaatatca gcaaataatg taattatcct atcacctaat aaagtctttg
    81481 gagactatat ttccaatgtc cttcctgagc ttggagaaga gccattatgt gaattaagtt
    81541 ttgaaaatat agcagaggta caattagata gagttattaa ttttgaaagt gagaaagacc
    81601 cattagaaat aaatgatgct aaatggtctg aaagagtgcg ttttaaatct acacttgatt
    81661 ttgtaaaact tattgatgat tatataaaac aaatgccaaa taagattttt attccaaaag
    81721 actacacttt tggaagtttt acagctaaaa gtgactggat acagagtaga tttgaggcat
    81781 ataacagata tccagttaag aagagattag agaaggtagc tgaagacatt cattataaat
    81841 ttgaatcaga taatattatg gaagaagatt taccaaaggt aaaaagtata cttaaaagtt
    81901 tgaatggaat gttgacaata aaaaatactc ttacactata taaggatttc tttaaacaaa
    81961 tgaatatatc aaacatgttt gtgatggcaa caaaaaaaac tcttgaatgg tcagatgtat
    82021 acccatttat atatattcat gctgcatatg aaggtataca agaagataag attataagac
    82081 atgttgttat tgatgaaatg caggattaca cacctattca atatgctgta ataaacttac
    82141 tttttaagtg taaaaagact attcttggag attttggaca attggttaat cctaatcaca
    82201 ctcatacact agatgatatg aaacagctat ataatgatgg ggaactagtt atgttgaata
    82261 agagttaccg ttctactttt gagattatta atttcgccaa aaagattcaa gacatatctt
    82321 cattagagcc tattgaacga catggtgaag aaccagcttt attaaaatgt aataacgagc
    82381 aagatgaaat aaataagata aaaatagaaa ttgaagaatt taaaaagagt gataatgcga
    82441 ctcttggtat tatattaaag acagataatg acgctaaagc tgtatatgat gcgttaagag
    82501 aaaaatatag tgttcactta atatcttctg aaagttctag ctttacaaaa ggagtatcca
    82561 taacttctat taaaatgtca aaaggtttag agtttgatga agttattgta ccttcagtaa
    82621 ataataaaac atattatagt gattatgacc gcagtttgtt atatattgct tgtacacgag
    82681 ctatgcataa acttaagttg acatatactg gtgaattgac tcaacttata gatatgtaga
    82741 ttatatactt attatgtaag tgtttactta tataaatata acctgtcaat aaaattcatt
    82801 aataaatcaa taaaaacaat atttgtaaaa gtaaaagcta taaattatat attaaatttt
    82861 ataatttata gcttttataa tactgcttat cttaatcctc ccaatagcaa aataatttta
    82921 aacatgccat attttataaa tgtaataaca attatacaat taaaataact ttcccaaact
    82981 aacttgacat ttaaaactta ctattgtaat atttaaatat tacaatagta agttttaaat
    83041 gtggaatcaa ttattatatc acaaattaaa aggaggacag gatgttatta atagttactt
    83101 aattatcttc gcaataggtt taatcaacat aattgtacta ggtgaagaaa atataagaga
    83161 tacagctatt catttagtct tgtttcttat aagtagaacc tagattggag tatattacaa
    83221 ataatgtcta ctattttaat agtaggttat aaatttaaat atgggagatg atataaatta
    83281 tgaaaagaaa aaagaatttt atttggatag ctatcttatt ggttggtgta gttatggtaa
    83341 tgtattatgt agggaaaaaa cataacgata taaatcaaaa aactgataag aattatataa
    83401 aatctgaatt aaataagtct gaattaaata aatccaaaat tgaaaacaat aataaaaaca
    83461 aaaaagaaaa aattaatatg gttgactata gtgattgttt tgaaggtatt agtggaggag
    83521 ctatttttta taatactaaa aataaagaat ataatatata taacaaagaa ttaattgaaa
    83581 caagaaggtc accatgttct acttttaaaa tagtttcaac tttaattggt ttagaaaaag
    83641 gggtaataaa ctcaaaagaa tcagttatgg gatatgatgg tacagagtat ccaaataaaa
    83701 attggaataa aaatcttagt ttagaagagg catttaagga gtcttgtgtt tggtactaca
    83761 aaaaattgat agataaagtt gatgctaaat ctgtccaaaa cattttagat gatttaaagt
    83821 atgggaattg cgatattagc gaatgggaag gagatttaaa aaatggaaag ggacatttaa
    83881 atggattttg gttagaatct tcattacaaa tatctccaaa agaacaagtg caaacaatgg
    83941 caaaaatatt tgagggagat acaaacttta aaaaagagca tattaatatt ttaagagata
    84001 ttatgaaaat agatgtaaat gataaaaaca taaatgtata tggaaaaact ggaacaggat
    84061 ttgatgaaaa aaataaacgt gtggatgcat ggtttgttgg tatgctagag cgtgaaggtg
    84121 acacctatta ttttgctatt aaatcagatg attccaataa agaaattaca gggccaaagg
    84181 taaaggaaat tgcaattaat ataattaaga aatattatag tgtaagggaa taaacttaat
    84241 tttatttgta aatattattt acctatagtc tgtaatattt attaaataat tttactaaat
    84301 tgagtctata tagagcaaaa ctcctttagt acataaaata cttgctattg attattaaat
    84361 tgaataccta tagatttaaa gttaatacct tttaaagact atgtaatata ttaaaagtat
    84421 aaataaaata tattgcatag tttttgtttt atattataat tttaaataat gtgcaaaaac
    84481 taaacaatat ttttaatagt aatttatatt tgtattcatg tcactataat gtcattttag
    84541 gttgctaaaa tttaaccata aaggagatga ttgtatatgg aaatattaaa atgtgaaaat
    84601 ctcacaaaaa tatatggttc aaatcaaacc agagtgacag cccttaataa tgtaaattta
    84661 tcagttcaaa aaggtgattt tgtatccatt gtaggagcat ctggttctgg caaatctaca
    84721 ttgttacatc tgcttggggg agtagataga cctacatctg gaaagattta tgttgaagat
    84781 acagaaatat caagtttaaa ggaagaagct cttgcagttt ttagacgtag aaaagtaggt
    84841 cttatttatc aattttataa tcttatacct acccttgatg ttagaaaaaa tatattatta
    84901 cccatgttac ttgataaaag aaaggtggat gaggatagat tctctgagat tgtatctata
    84961 ttgggattat ctgatagatt aaaccatctt ccaagtcaac tttcaggtgg acaacaacaa
    85021 agggtatcta tagctagaag tttaatctat agaccagcta ttttattagc agatgagcca
    85081 actggtaatc ttgatagaaa aaattcagaa gaaattgtag acttgttaaa cttatcaaat
    85141 aaacgattta atcagacaat acttcttatt actcatgatg agaaaatagc actagaggca
    85201 aatcgtattg taactatgga agatggagtg attgtctctg aaaaggtggt gaagaaatga
    85261 atattcttca agaatacacc ttagactttg tacgacgcaa taaacgtagt agtatagcta
    85321 taatgttagc tatattactt actacaacca tgatgtcttc tttgtgtgga ctgttgtata
    85381 ccatgtggac agattttata aaactttcaa ttgagaaaga aggtaactgg catggtgaat
    85441 tgtttgacta tacttatgga agtgacttac cattaattga aaatttttct tcagttgatg
    85501 atgtaatggt aaaaggacaa tggtatgtag gcaaaattaa tgatgagaaa agagattata
    85561 taatttatag aaatgctaca tcagagtatt ggaattctat gccagaaaag gatactataa
    85621 tagagggtcg tcgaccaaat aatgctaatg aaattgcatt atcaaaacaa tattttgaga
    85681 ataatccaag tgtaaaaatt ggtgataaaa ttactctccc aataggagat agaatcctaa
    85741 atggaaagcc tcttgaaccc atagccccaa aatcgaaagg ggaaagtttt aaaaaaattt
    85801 cagaggctac attgacaata gtaggaaagg tagatgtttc tacttcatca gtaatacctg
    85861 catatacagc tcttggatat cttgataaaa caagtataaa acctaatgat agtataactg
    85921 tgtacttgcg atttaaaaat ataagagaca cgtataagga acttccaaaa cttgctaaat
    85981 cattgggatg gaagactaat gaatatggaa aatacaatct taaatacaat agtaattatc
    86041 ttttaaagat gttagtcttt tcaccagaac agaaagcatc tatgagtagt atatcaaaat
    86101 tttcaactcc tattatgtat cttacaatag caatttttac agtagccgtg tttgtaatgg
    86161 tgatttacaa cgcgttttca ctgtctgcaa atgctagact tactcaatta gggatattat
    86221 ctagtgttgg tgcatcacca aaacaaatta aaaggtctgt agtgtttgaa ggctttttac
    86281 tgacaattat accattacca ataggtttat ttttaggatg gttattgtgt aataggctta
    86341 tagtttatgt taattcagtt aattatcata ctgatgttcc agaagtggta tttacttatg
    86401 gtattcctgc ttttctgcca gcagttttac ttacaatagt aacagtctgg atttctgcac
    86461 ttataccagc acgaaaagta tcaaagatat ctcctataga agcaatacga caaggagata
    86521 gtgttaaaat caaaaagtcg cataaatatt cattaggaaa gatatttgga atagaaggag
    86581 aacttgcatc aaacgcacta cgtgctcgta aaaaatctta tcgtactgca acaatatctt
    86641 taacattatc ttttttatta cttacatgtt ttttgcatat aattgcaaat caagaaggag
    86701 caaaagctgt ttatggaagt gataattata aggaccaaag agatatagca gtttatttgg
    86761 aaaatagtga acctgtagag tctgctttca ttgaaaaatt agataataca gaaggtgtaa
    86821 aaagttcact atattatcaa aaaatgtctg cttccacttg gttgactgaa aaagatgctt
    86881 caaaagaact tgcgaaaaat ggaggattta aaaatatagc ttcatctaaa aagtactctc
    86941 ctatagaacg tgatggcaag tttcgtataa tttcaaatat aattgggctt gatgataaga
    87001 gttttacaga atattgtagg caaatttctg tagacccaaa gttattttat gatacaaaaa
    87061 atccaacctc aattgtatat aataaggagg aagatattaa tcgtagtaca cgtagaaata
    87121 aagtatatat agattattta aatctttcaa taggagataa cattaaatta aatgaaaaag
    87181 tatatgacga agataaaggg gattatactt acaacatgaa agtgggagct attacaagca
    87241 cacttcctaa aatagtagat actagttcaa agtatacatt aatgcaaata gttccaatgt
    87301 ctatggtgca ggaaatatct aaaaattatg atgaagtaag taggttacgt tcaaataggc
    87361 tgataggagt atttaaagta aataatcgtg aggacattcc tagagtaaga gaaaaattag
    87421 agtccattta taataaagac tatggttcag gagattatag tattgaggat gttttagaaa
    87481 gtgaaaaaca aaaggctagt ggaataaaga ccatgaattt aatagtaggc tttattacag
    87541 gtttattggc tatgattgga ttatcaaatg tacttgctac agtgtcagga aatattagaa
    87601 gtagacgaca agagtttgct atgttgcgtt ctgttggatt atctccagaa ggcataaaaa
    87661 agatgcttat tttggaaggt ttattcttag gaattacacc attactactt agtattcctg
    87721 tgcaaatagg aatagtgtat gcttttctac gtataaatga aatatatttt atagagtatt
    87781 taccatttgc acctatatct acaataatag gttttactat attgatactt tttattgtaa
    87841 tagcatcata tatgacagga tacaagcagt tgaagaatga aaatatagta gaatctataa
    87901 aaaatgaaac aatataaaca aaatctattt gaacttattt aaaggtttcg atttaagact
    87961 acttacaagt atagggatag ttaagttgtt tgtttaataa aaccttaaat gtaaatagaa
    88021 gtatattact aaaacaatag ataacataga atatagatat agctggatta taggtatttt
    88081 acctataatc cagcatttta tgtgtaaaat ttaattatga atcttgcacc accattatgg
    88141 caattttctg catgtagagt accattttga cgttctataa tagactttga tagagcaagc
    88201 cctataccaa tactgtcctt actagcattt ttaccacgat aaaatctatt aaaaatatat
    88261 ggaagttctt cctgagcaaa ccccttacca ttatcttcta tgataatctc aacatataga
    88321 ggattttgac tataataagc aactatatat ccaccatctt ctatatgctc actacaattt
    88381 ttaagaatat ttaaaagagc ttctaaagtc caattaatat cgatttcaaa ttctaccgaa
    88441 ggagaagcct cgatagtaaa tgtctgatgt ttttctctta aagaaccttc tataggctca
    88501 attgcataag taagaagaga atgtacatct ataagtttgc tttcaaatat taaagtactt
    88561 gcatccaatt ttgataatgt aagtaaagat gaaactagtc tctcaagtct tgagatttga
    88621 tttgtaagtc tgttaatata atctatttct tcatctggac aattttctga aagtaattgt
    88681 gccataagtg acatagaggt aattggagtc ttaagttgat gagcaatatc tgcaaggtta
    88741 tctgaaagag tttgtctttc ttttaaagca aattcttttg aacaacgaag ttccccaact
    88801 gttttatata tctcatcttc aaggtgagaa aattcatctt cacatcgtaa aagtacagac
    88861 tcttttccta aattcacttc ttctaagtat tgagtaagat tgtttattct actcagtttt
    88921 tgcttatttg ttctatgttt gattatatat acaactgtag ccattgttga aattatacca
    88981 aacgatatca ctagaaaata aaaaaagttt ttactccaaa atgtactttt agaatatcca
    89041 tgttttgata aaatttcatt tcctgtttta aaatccttat cactagaatt tttcagtgat
    89101 tttagtatac tttctgtaga cttaggattg tactcatatg atgcaccaag agccttagac
    89161 agtacattgt attcattaaa agaagttata gttgttagaa ttacactcaa taaaaaagtt
    89221 acaattaagc agaatattat aaaaacaact gtactgttga tatttcttgg agttttcact
    89281 agttgtcctc cattctatat cctatgcctc ttaatgtttt tatacaaggt ggatttttta
    89341 atttttctct aagacgtttt attgtaacag taagagtgtt atcatttacg aaattaccat
    89401 ctacatccca gagcatttct agtaactttg tacgagtcat agctctattt ttattttcca
    89461 taagacttag aagaagttta tattctcctg ctgtcaaagg tacttcaaca ttatctaaat
    89521 atgctttgac ttcaacctta ttcaagctta tattttcaca tgtaatagta ttgttagtat
    89581 ttgaatgagt tcttctaaga actgcattaa ttctggattg aagtactgag agcaaaaacg
    89641 gtttaaccac atagtcatct gcacccatat ctaatccacg tataatgtct ttttcatcat
    89701 cacggactgt caaaaatatc actggagtat cttctatact tttaacatat tggcaaaact
    89761 cgtatccaat accatcaggt agatttaaat caagcagaat taaatcaata gttttatcaa
    89821 aatttttttt agcttcagca atcgtattat aacaacatac agtgtgattt ttcttttcaa
    89881 gggaagtttt tattccaaat gtaattgtat cattatcttc taaaagaagt attttagcca
    89941 tttactttta atcctttcag taatttagtt attccattaa ctaagttatt agttttatgt
    90001 ttaatatttt tcatattaga gatagaaaaa attatcattt aagtatataa actttaattt
    90061 ataaacttag gtttatgctt taattgaatc tattaaaaga gcaagagttg tttcaataaa
    90121 tttttcctca tctatattaa agttgttcag gtatgatttt cctgttacag atagtaaatt
    90181 aaaaaatcct gtaagtgtaa atattgatga atacataaga gtaggtattt caatatcatg
    90241 cctaatactt ctatcatttt ttccaatttc aaacattcct tgtatttcat caaacataaa
    90301 tttattaaaa gaaaaaaact tttctttaaa cagcatatca gtatccgatt tttcagagtt
    90361 tacaatacca atcattccca taaggcataa tagagaaggt tctacagagt aaaatttatg
    90421 aaaagcaaag tatgaaagtt ttattttttc aaaccctgtt ttgccttttg cactttctat
    90481 tttaacatta tcccaaagtc ttttatatcc tcttaagaca acagcaaaga ataaatcttc
    90541 tttacatgaa aagtacttgt atatggtgcg tttagtatat tcaacttctt ttgctaattc
    90601 attcatagtt gtattatcaa atccattaag acaaaataat ttttctgcct tatcaataat
    90661 ctcattttct ctttgtattt tttctttatc tctttttgat aattctgaca tataaattat
    90721 tcctttctat tgataaaaaa gtatactgat ggtatattta tgtaaatata atatttgtat
    90781 acctatagta tactttaata aaaaataaaa ttaatatcaa gtattataac tatttataac
    90841 tttattaatt aattatatag gtaaaatacc aaataagggg aatttattta tgaagataaa
    90901 agaaaatgta ttaatgttag atagtactcg tggctcaaat tgttttattg tgtttgataa
    90961 agaaattatt cttatagaca caggtcttcc ttttatgggg aaaaatataa ttaaagaatt
    91021 aaaaacactt ggcattaaac ttacagatat taagcatatt ttattaactc atcatgatgt
    91081 tgaccatata tctaatatta aattattgaa agaaaaaaca ggagcaaaag tatgggctca
    91141 tgtagaggat atacctttta ttataggaga gaaggataga cctgggttta agaagtttat
    91201 tggaaaggca atttccagaa ggctcattaa ggatgttgaa ccttatggag agaatatgca
    91261 gattgggaat ataaaaatta tccatactcc tggtcatact ccagggcatg tctgcatgat
    91321 ttttgaagat gtattatttg caggtgattt agtcaaaaat aagaatggaa atatagttcc
    91381 ttatcctaat ccatggaatt gggattataa aaagatgatg aaatctataa gagaattgga
    91441 taatttaaaa tatgaatgga tatgtatgtc tcatggaact ccttgtatta aataataaaa
    91501 attaacatgg attaatagag gcgtagttgc ttgtatgtat gataataatt tacagcttct
    91561 ttttaatata tcatgtatat ttgtagctgt aagcatattt ataacaatac ttacaatttt
    91621 gtattttaac atctataata ataattttag ctttgttaac tatgaaattt acttaaagaa
    91681 gtaaatattc aagtagtagt aattattaaa taagataaaa aataaatggc agatgaatta
    91741 aagtaatttc taccatggaa aatacttttg agttagaaaa aactctattt tagagtatga
    91801 agagatgaag cttccgaaga aagcaatatc taaagtacat gttcgaaagg ataagtactt
    91861 tttggtgcct gcttttagca ggttattttt attttaataa aaataaaatc aaatgattat
    91921 tttatcctta ttatttaaaa ctcttcccta gaaaaagcaa ctaatgtata ttaaaataat
    91981 atttagggag tggaaaaaat gagattagaa tcgttagtta accaaaatta tgataattta
    92041 aatgaaaatg ataaaattat tattaaacaa atattgattt gtcaaagaga ataccgtaat
    92101 ttttcgtgtg aaaaaattgc aaatgaatgt aatgtttcta gagctacttt attaaggctt
    92161 tgtagaaaaa ttggattaga ttcattctct gatttaaagt atttacttaa aaataatcaa
    92221 ctagaatttg ttaataatga taataatttt catgatgttt gcgagaatta tcgactatta
    92281 atgaatgaat tacaaaaaat atcatttcaa gatatttgta aaataatata tgatgcagaa
    92341 acaatttata tttatgggac aggtaatgaa cagaaaagtt tagctcaaga aataaagaga
    92401 atatttcttt cagtaggtaa atgtgttatt gacttatttg atataggtga aattgaattt
    92461 atgagagaat catttcaaaa aagtgattta tttattatca tttctttgtc tggagaaaca
    92521 aaagcaggaa ttgaaattgc aaaatttatc aacaatcata tacatacgat ttctttaact
    92581 aggcttgata ataatacaat tgcaacactt tgtgagtata atctgtatgt tgaaactcaa
    92641 aaacttgata cattacaagc tatatcttat gaagtcgtag gagcatttta tgctctatta
    92701 gatttgcttc atatgaatta catagagtat agaaggagaa aagaatgaaa attgaaggac
    92761 ttttcaataa atattataat tcatttacag caaatgataa gtatatctgt gagtgtattc
    92821 ttaatcataa agaagattgt attaaacttt ctatagatga atttgcagac aaataccata
    92881 tatctacaag tgcactttct cgttttgctc aaaaactaca attacctgga tatagtgaat
    92941 taagagttat tatacgctta aatgaaacag aagtagaata taaaaatcaa agtaaacacc
    93001 aattaatgga ttgctataat aaggtgataa atgatataga gaagaaggat tgttcgatta
    93061 tgtttgaaag aatgaaaaag gcaaatcgta taatcgtctt tggagaaggt tattctcagg
    93121 aaagagttgc taaagagatg aaaaggattt tcttaccaac agggaaaatt atatatgatg
    93181 tttatggtta tgatatgatt caggcactta atcattttat aaaaacagat gatatgattt
    93241 tctttatttc attgaatgga gatgcatcta caattattga ttttgctaaa gaaatgagaa
    93301 tgaaaggaat ttatatggtt tctattacaa aaatgataag taatccttta gcaagattat
    93361 gtgatgaaaa cctgtatatt caatctatat ctatttctgt agataaacaa ctggactacg
    93421 atgtaacaac accttatttt attttaattg aactgcttta tattaaatac aagatgtatt
    93481 tagaaagtga acatattccc cgaaaatgaa aatttgtgct aaaaatgaac atatttttta
    93541 aaagatatca aaatattgat atcttttttt ttgaatgcta ttatgatttt gatagtaaga
    93601 aaggaagatg aaattgtaca aattattaat acttgatata gatggtacgc ttagagatga
    93661 ggtatatgga atcccagaat ctgcaaagca tgctatacgt ttatgtcaaa agaatcattg
    93721 cagtgttgtt atttgtactg gaagaagtat gggtacaata caagatgatg ttttatcatt
    93781 aggagttgat ggatatattg caggaggagg taattacatt caatatcatg gtgaattact
    93841 ttataatcaa tcttttaatc aaagattgat aaaggaagtt gtttgtttat taaaaaatag
    93901 agaagttgct ttttcgattg agagtcagga aaaagttttc atgaatcaaa aagccaaaga
    93961 aatatttgaa acaatgaatc agttgaaagg aactaattct tgtataaata aacaacatat
    94021 ccaagaaaaa ataacatatg aaaataacat tgaagagtat aagtcacaag atatacataa
    94081 aatttgttta tggtcaaatg aaaaggtatt tgacgaagtg aaagatatac tacaagataa
    94141 aatggaatta gcacagagag atatttctag tcagtattat gaaattattc aaaaagattt
    94201 tcataagggc aaagcaatta agagattaca agaaagatta ggagtaactc aaaaagaaac
    94261 catatgtttt ggtgatggtc aaaatgacat tgtcatgttt caagcatcag acgttacaat
    94321 tgcaatgaaa aatagtcatc aacaacttaa agatatagcg acatctatat gtgaggacat
    94381 attcgataat ggaatttata aagaattaaa aagaagaaat atcatataaa aaggagtaat
    94441 ttatggaaaa gaaatggtgg caaaaagaaa tcgtttatca aatttatcca agaagctttc
    94501 aagatagtaa taatgatgga attggagatt tacagggaat tatttctcgt ttagattatt
    94561 taaaagattt aggtattaca tcattgtggt tatgtccaat ttttaaatca cctatggatg
    94621 ataatgggta tgatattagt gattatttgg atattgcaag tgaatttgga agtatggaag
    94681 atttaaaaga gttaattaaa aaaagtaaag atagaggaat caaaattata ttagatttag
    94741 ttcttaatca tacaagtgat gaacatcctt ggtttcaaga agcattaaaa aatccagaaa
    94801 gtccttatca tgattattat atttttaaaa aaggaaacga tttgccaaat aactggaggt
    94861 ctgtttttgg tggaagtgtt tgggaaaagg tagagaatag agacgaatat tattttcatt
    94921 cttttggaaa aaaacaacct gaccttaatt gggaaaatcc aatattaaga agtgaacttt
    94981 accaaatgat taatacctgg tctcaaatgg gagtggcagg atttagagtt gatgctatta
    95041 cattcatcaa aaagaattta agttttcaaa gtttagaaag tgatggtgtt gatggtcttg
    95101 ttaaatgtac aaaaacagtt agaaatcagc ctggaataga aaaaatgctt tatgaattaa
    95161 aagaaaatac gtttaaaaaa tatgattgta tgactgttgc tgaagcagca ggtattagct
    95221 atgaccagtt aggtgatttt attggagaag atggtttctt ttcaatggtc tttgacttta
    95281 aacatgctga cttagatgtt gcttctggta gtgagtggtt taaaagaatt tcatggacaa
    95341 ttccagattt aagaaaatgc attttagata gtcaaatgta tgttcaggaa catggatggg
    95401 cagctaattt tattgaaaat catgaccaac caagagctac aacaaagtat cttttgcaat
    95461 acgaaaggaa tgatgatgca gtaaaaatgt tgggagcaat gtatttcttt ttaagaggaa
    95521 ccccatttat ttatcaggga caggaattag gaatgacaaa ttttaaaaga gataccataa
    95581 atgattttaa tgatttatct agcattgacc aatactatcg ttcaatagat gaaggttact
    95641 cagaagaaga agcgttagaa tttgtgaatt taagaagccg agataatgca agaacgccat
    95701 ttccatgggc agataaagaa aatgcaggtt tttcagatac aacaccatgg ttaaaggtta
    95761 ttgaaaatta taaagatatt aatgcacaga gtcagattaa caattcagag agtattttag
    95821 aattttataa aaagatgata aagttgagac aagatagtga gtattctgat tgtttgattt
    95881 atggttcaat agaacctatt gatatagaaa gtgatgatat tattgcgtat agaaggcaat
    95941 tagatttggt agttattgat tgttattata atttttctga taaacctgta gaaataagag
    96001 tagaagaaaa atatgatatt gtattccaaa atttagatga tataaatcta ttaaataaaa
    96061 cagtgcgttt gaaaccattt catgcagtat tattgaaagt gaggtagaaa aatgaataaa
    96121 tataataaaa tagcaaatga gcttattaaa attattggtg aagataatat tatttctatt
    96181 acacattgtg ccacaagatt aagagtgatg gttaaagata gagaaattat taatgataag
    96241 aaagttgaaa aagttgatga ggttaaaggg gttttcttta cttctggaca gtatcaaatt
    96301 attttaggaa caggaatagt taataaagtt tatgcagaag ttgaaaaaat gggattaaaa
    96361 actttatcaa aaaaagaaca agatgaatta gttaaaaata atgaaactgg atttaagaaa
    96421 gttatgagaa ctctagcaga tatatttgtt cctattattc cagttattgc agcaacagga
    96481 ttattcttgg gattaaaggg ttgtttgttt aatgataatg tacttggatt atttggaatg
    96541 tcttctgcaa atattccatt gtatattcag acacttgttt cggttcttac agaaacagca
    96601 tttgcttttt taccagcaat tattgtatgg tcagcattta aagtatttgg aggaacacct
    96661 gttattggac ttgttattgg acttatgtta gtttccccaa tacttcctaa tgcatattct
    96721 gttgctgacc catcaaatga aattgaagca attatggcat ttggatttat tcctattgta
    96781 ggttgtcaag gaagtgtttt aacagctatt gttacagcat ttattggagc taatcttgaa
    96841 aaatggttcc gtaaacatat gcctaatgta ttagacctta ttttcacacc attttttgtt
    96901 atgctaataa caatgttagt tattttgtta ggtgtaggcc ctataatgca tacaatagaa
    96961 ttaaaaatgg ttgatatcat cagcttattg attgatttgc ctttaggaat tggaggattt
    97021 attattggat ttacatatcc attagctgtt attactggct tacatcatac ttatgtaatg
    97081 attgaaacat cactattagc aaatacagga tttaatgccc ttattactct ttgtgcaatg
    97141 tatggatttg cgaatattgg aacatgtcta gcatttatga aaaaatctaa aaataatcaa
    97201 gttaaacaaa ctgcagttgg agcaatgcta tctcaacttt ttggtataag tgagcctgtt
    97261 ttatttggga ttcagcttcg atataattta aagcctttga ttattatgtg tgcatcttca
    97321 ggtttaggag cagcaatatt atcaatttta catattcaat ctaattcata tggattagca
    97381 gttttacctt cttatttaat gtatatctat gatggatata atttaatcac atacttatta
    97441 gcatcaatat ttgtggttgc attctgcttt attgtaacat gtttatttgg agtgcctaaa
    97501 gaagctataa atgaagatga agacgaagaa ttagtgttta atgaaaataa tgaaaacttt
    97561 gtgtctccag ctaaggggaa aattgttgca ttagaaaatg taccagatga aacattttct
    97621 aaaaaaatgt taggtgatgg ttttgctatt gatattatag atggaaaaat tgtttctcct
    97681 atttcaggta aattagaaac agtggtttca agtggacatg catttgggat taaaggaact
    97741 aatggagaag tattaattca tgttggaatt gatacagttg cattaaatgg agatggcttt
    97801 gatattgctg ttaaacaagg agatatggtt aaacagggag atgttcttgt taatgttgat
    97861 ttaaagagaa tacatgaatt aggaaagtct actttaacaa tggtattgtt tccagatggt
    97921 aagaaggtaa atattttgga tataaacaag gatgtaaaaa taggtcaaag aatatgtgtt
    97981 gagtagtagg tgatatgtaa tgactacaaa agaagattat caagagtaat tcaatctttt
    98041 taaagtatga gaaataattc ataaactcta aaacaattaa agaggttgtt tcaaaataga
    98101 gattgtattg cacccaaatt gttgaaatga tgaaaatata tttaacttca tacaaaaaat
    98161 taaatagtgg ca
//
LOCUS       DAYAKB010000004        95742 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.004, whole genome shotgun sequence.
ACCESSION   DAYAKB010000004 DAYAKB010000000
VERSION     DAYAKB010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 95742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.004"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            766..903
                     /gene="rpmH"
                     /locus_tag="ACGI3L_000341"
     CDS             766..903
                     /gene="rpmH"
                     /locus_tag="ACGI3L_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFG9196076.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            981..1325
                     /gene="rnpA"
                     /locus_tag="ACGI3L_000342"
     CDS             981..1325
                     /gene="rnpA"
                     /locus_tag="ACGI3L_000342"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFG9196077.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            1357..1608
                     /gene="yidD"
                     /locus_tag="ACGI3L_000343"
     CDS             1357..1608
                     /gene="yidD"
                     /locus_tag="ACGI3L_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFG9196078.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            1640..2347
                     /locus_tag="ACGI3L_000344"
     CDS             1640..2347
                     /locus_tag="ACGI3L_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFG9196079.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            2316..2945
                     /gene="jag"
                     /locus_tag="ACGI3L_000345"
     CDS             2316..2945
                     /gene="jag"
                     /locus_tag="ACGI3L_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFG9196080.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            3057..4436
                     /gene="mnmE"
                     /locus_tag="ACGI3L_000346"
     CDS             3057..4436
                     /gene="mnmE"
                     /locus_tag="ACGI3L_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFG9196081.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            4531..6426
                     /gene="mnmG"
                     /locus_tag="ACGI3L_000347"
     CDS             4531..6426
                     /gene="mnmG"
                     /locus_tag="ACGI3L_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFG9196082.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            6419..7138
                     /gene="rsmG"
                     /locus_tag="ACGI3L_000348"
     CDS             6419..7138
                     /gene="rsmG"
                     /locus_tag="ACGI3L_000348"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFG9196083.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKDEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            7301..8086
                     /gene="noc"
                     /locus_tag="ACGI3L_000349"
     CDS             7301..8086
                     /gene="noc"
                     /locus_tag="ACGI3L_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0032466 - negative regulation of
                     cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HFG9196084.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            8221..8994
                     /locus_tag="ACGI3L_000350"
     CDS             8221..8994
                     /locus_tag="ACGI3L_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9196085.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            8996..9859
                     /locus_tag="ACGI3L_000351"
     CDS             8996..9859
                     /locus_tag="ACGI3L_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFG9196086.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            9892..11034
                     /locus_tag="ACGI3L_000352"
     CDS             9892..11034
                     /locus_tag="ACGI3L_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9196087.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(11168..11743)
                     /locus_tag="ACGI3L_000353"
     CDS             complement(11168..11743)
                     /locus_tag="ACGI3L_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HFG9196088.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            12003..13295
                     /gene="rstA"
                     /locus_tag="ACGI3L_000354"
     CDS             12003..13295
                     /gene="rstA"
                     /locus_tag="ACGI3L_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin production/motility transcriptional
                     repressor RstA"
                     /protein_id="HFG9196089.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            13400..14002
                     /gene="yedF"
                     /locus_tag="ACGI3L_000355"
     CDS             13400..14002
                     /gene="yedF"
                     /locus_tag="ACGI3L_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HFG9196090.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            14075..14338
                     /locus_tag="ACGI3L_000356"
     CDS             14075..14338
                     /locus_tag="ACGI3L_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HFG9196091.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            14353..14538
                     /locus_tag="ACGI3L_000357"
     CDS             14353..14538
                     /locus_tag="ACGI3L_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFG9196092.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            14641..15837
                     /locus_tag="ACGI3L_000358"
     CDS             14641..15837
                     /locus_tag="ACGI3L_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9196093.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            16051..16329
                     /gene="rpsF"
                     /locus_tag="ACGI3L_000359"
     CDS             16051..16329
                     /gene="rpsF"
                     /locus_tag="ACGI3L_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFG9196094.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            16366..16800
                     /locus_tag="ACGI3L_000360"
     CDS             16366..16800
                     /locus_tag="ACGI3L_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9196095.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            16819..17046
                     /gene="rpsR"
                     /locus_tag="ACGI3L_000361"
     CDS             16819..17046
                     /gene="rpsR"
                     /locus_tag="ACGI3L_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFG9196096.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            17189..17509
                     /locus_tag="ACGI3L_000362"
     CDS             17189..17509
                     /locus_tag="ACGI3L_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFG9196097.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            17517..18473
                     /locus_tag="ACGI3L_000363"
     CDS             17517..18473
                     /locus_tag="ACGI3L_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HFG9196098.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            18484..20478
                     /locus_tag="ACGI3L_000364"
     CDS             18484..20478
                     /locus_tag="ACGI3L_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFG9196099.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            20479..20928
                     /gene="rplI"
                     /locus_tag="ACGI3L_000365"
     CDS             20479..20928
                     /gene="rplI"
                     /locus_tag="ACGI3L_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFG9196100.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            20947..22275
                     /gene="dnaB"
                     /locus_tag="ACGI3L_000366"
     CDS             20947..22275
                     /gene="dnaB"
                     /locus_tag="ACGI3L_000366"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFG9196101.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            22480..22788
                     /locus_tag="ACGI3L_000367"
     CDS             22480..22788
                     /locus_tag="ACGI3L_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196102.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            22870..24159
                     /locus_tag="ACGI3L_000368"
     CDS             22870..24159
                     /locus_tag="ACGI3L_000368"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFG9196103.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            24485..24560
                     /locus_tag="ACGI3L_000369"
     tRNA            24485..24560
                     /locus_tag="ACGI3L_000369"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24518..24520,aa:Lys,seq:ttt)
     gene            24567..24641
                     /locus_tag="ACGI3L_000370"
     tRNA            24567..24641
                     /locus_tag="ACGI3L_000370"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24600..24602,aa:Glu,seq:ttc)
     gene            24646..24721
                     /locus_tag="ACGI3L_000371"
     tRNA            24646..24721
                     /locus_tag="ACGI3L_000371"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24679..24681,aa:Val,seq:tac)
     gene            24755..24829
                     /locus_tag="ACGI3L_000372"
     tRNA            24755..24829
                     /locus_tag="ACGI3L_000372"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24787..24789,aa:Thr,seq:tgt)
     gene            complement(25212..26204)
                     /locus_tag="ACGI3L_000373"
     CDS             complement(25212..26204)
                     /locus_tag="ACGI3L_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9196104.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(26213..27271)
                     /locus_tag="ACGI3L_000374"
     CDS             complement(26213..27271)
                     /locus_tag="ACGI3L_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFG9196105.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            27396..28859
                     /locus_tag="ACGI3L_000375"
     CDS             27396..28859
                     /locus_tag="ACGI3L_000375"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HFG9196106.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            28961..29758
                     /locus_tag="ACGI3L_000376"
     CDS             28961..29758
                     /locus_tag="ACGI3L_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9196107.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            29771..31873
                     /locus_tag="ACGI3L_000377"
     CDS             29771..31873
                     /locus_tag="ACGI3L_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9196108.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            31941..32420
                     /gene="rlmH"
                     /locus_tag="ACGI3L_000378"
     CDS             31941..32420
                     /gene="rlmH"
                     /locus_tag="ACGI3L_000378"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFG9196109.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            32569..32880
                     /locus_tag="ACGI3L_000379"
     CDS             32569..32880
                     /locus_tag="ACGI3L_000379"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196110.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            32928..33245
                     /locus_tag="ACGI3L_000380"
     CDS             32928..33245
                     /locus_tag="ACGI3L_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9196111.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            33458..34159
                     /locus_tag="ACGI3L_000381"
     CDS             33458..34159
                     /locus_tag="ACGI3L_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9196112.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            34383..35684
                     /locus_tag="ACGI3L_000382"
     CDS             34383..35684
                     /locus_tag="ACGI3L_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9196113.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            35821..36915
                     /locus_tag="ACGI3L_000383"
     CDS             35821..36915
                     /locus_tag="ACGI3L_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFG9196114.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIILLDFIEPWSKFKLILEGE"
     gene            36917..38050
                     /locus_tag="ACGI3L_000384"
     CDS             36917..38050
                     /locus_tag="ACGI3L_000384"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HFG9196115.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELRRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            38068..39177
                     /locus_tag="ACGI3L_000385"
     CDS             38068..39177
                     /locus_tag="ACGI3L_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HFG9196116.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLRGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            39242..39982
                     /locus_tag="ACGI3L_000386"
     CDS             39242..39982
                     /locus_tag="ACGI3L_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HFG9196117.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGILSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            39987..40979
                     /locus_tag="ACGI3L_000387"
     CDS             39987..40979
                     /locus_tag="ACGI3L_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HFG9196118.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYITTGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(41167..42048)
                     /locus_tag="ACGI3L_000388"
     CDS             complement(41167..42048)
                     /locus_tag="ACGI3L_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9196119.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            42321..43709
                     /locus_tag="ACGI3L_000389"
     CDS             42321..43709
                     /locus_tag="ACGI3L_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LVIVD repeat-containing protein"
                     /protein_id="HFG9196120.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYANGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            43737..44690
                     /locus_tag="ACGI3L_000390"
     CDS             43737..44690
                     /locus_tag="ACGI3L_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9196121.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            44750..44974
                     /locus_tag="ACGI3L_000391"
     CDS             44750..44974
                     /locus_tag="ACGI3L_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196122.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            44967..45479
                     /locus_tag="ACGI3L_000392"
     CDS             44967..45479
                     /locus_tag="ACGI3L_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HFG9196123.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            45511..46365
                     /locus_tag="ACGI3L_000393"
     CDS             45511..46365
                     /locus_tag="ACGI3L_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HFG9196124.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            46899..47693
                     /locus_tag="ACGI3L_000394"
     CDS             46899..47693
                     /locus_tag="ACGI3L_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9196125.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            47797..48603
                     /locus_tag="ACGI3L_000395"
     CDS             47797..48603
                     /locus_tag="ACGI3L_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFG9196126.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            48665..49186
                     /locus_tag="ACGI3L_000396"
     CDS             48665..49186
                     /locus_tag="ACGI3L_000396"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFG9196127.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            49601..51688
                     /locus_tag="ACGI3L_000397"
     CDS             49601..51688
                     /locus_tag="ACGI3L_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9196128.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            51703..51990
                     /locus_tag="ACGI3L_000398"
     CDS             51703..51990
                     /locus_tag="ACGI3L_000398"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196129.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            52017..53288
                     /locus_tag="ACGI3L_000399"
     CDS             52017..53288
                     /locus_tag="ACGI3L_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFG9196130.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            53346..53945
                     /locus_tag="ACGI3L_000400"
     CDS             53346..53945
                     /locus_tag="ACGI3L_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9196131.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQEYLKWHPAGSLGKSIREGI"
     gene            53950..54855
                     /gene="dapA"
                     /locus_tag="ACGI3L_000401"
     CDS             53950..54855
                     /gene="dapA"
                     /locus_tag="ACGI3L_000401"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFG9196132.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKSQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            54961..55593
                     /locus_tag="ACGI3L_000402"
     CDS             54961..55593
                     /locus_tag="ACGI3L_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HFG9196133.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGLNIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNVRKI"
     gene            56070..58577
                     /locus_tag="ACGI3L_000403"
     CDS             56070..58577
                     /locus_tag="ACGI3L_000403"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9196134.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            58919..61081
                     /locus_tag="ACGI3L_000404"
     CDS             58919..61081
                     /locus_tag="ACGI3L_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFG9196135.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            61086..61703
                     /locus_tag="ACGI3L_000405"
     CDS             61086..61703
                     /locus_tag="ACGI3L_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196136.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            61892..62236
                     /locus_tag="ACGI3L_000406"
     CDS             61892..62236
                     /locus_tag="ACGI3L_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFG9196137.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            62806..63672
                     /locus_tag="ACGI3L_000407"
     CDS             62806..63672
                     /locus_tag="ACGI3L_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFG9196138.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPINK
                     ESGKPCINLQPDFKCSVHNSLIKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESMMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            63785..64189
                     /locus_tag="ACGI3L_000408"
     CDS             63785..64189
                     /locus_tag="ACGI3L_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HFG9196139.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            64353..64802
                     /locus_tag="ACGI3L_000409"
     CDS             64353..64802
                     /locus_tag="ACGI3L_000409"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9196140.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(64958..65335)
                     /locus_tag="ACGI3L_000410"
     CDS             complement(64958..65335)
                     /locus_tag="ACGI3L_000410"
                     /inference="COORDINATES: protein motif:HMM:NF018663.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9196141.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            65606..66514
                     /locus_tag="ACGI3L_000411"
     CDS             65606..66514
                     /locus_tag="ACGI3L_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HFG9196142.1"
                     /translation="MNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKCMNV
                     PIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSINAF
                     IKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINRLPV
                     LIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDIETL
                     NTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKYYLE
                     KTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            66998..68416
                     /locus_tag="ACGI3L_000412"
     CDS             66998..68416
                     /locus_tag="ACGI3L_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HFG9196143.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            68492..69304
                     /locus_tag="ACGI3L_000413"
     CDS             68492..69304
                     /locus_tag="ACGI3L_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9196144.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            69727..70344
                     /locus_tag="ACGI3L_000414"
     CDS             69727..70344
                     /locus_tag="ACGI3L_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HFG9196145.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(70501..70953)
                     /locus_tag="ACGI3L_000415"
     CDS             complement(70501..70953)
                     /locus_tag="ACGI3L_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HFG9196146.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            71401..72759
                     /locus_tag="ACGI3L_000416"
     CDS             71401..72759
                     /locus_tag="ACGI3L_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9196147.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            73032..73412
                     /locus_tag="ACGI3L_000417"
     CDS             73032..73412
                     /locus_tag="ACGI3L_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9196148.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            73537..73737
                     /locus_tag="ACGI3L_000418"
     CDS             73537..73737
                     /locus_tag="ACGI3L_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196149.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            73933..74661
                     /locus_tag="ACGI3L_000419"
     CDS             73933..74661
                     /locus_tag="ACGI3L_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196150.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            74683..75600
                     /locus_tag="ACGI3L_000420"
     CDS             74683..75600
                     /locus_tag="ACGI3L_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HFG9196151.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            75742..76926
                     /locus_tag="ACGI3L_000421"
     CDS             75742..76926
                     /locus_tag="ACGI3L_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9196152.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTYLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            77033..77221
                     /locus_tag="ACGI3L_000422"
     CDS             77033..77221
                     /locus_tag="ACGI3L_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFG9196153.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            77370..78020
                     /locus_tag="ACGI3L_000423"
     CDS             77370..78020
                     /locus_tag="ACGI3L_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9196154.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            78123..79061
                     /locus_tag="ACGI3L_000424"
     CDS             78123..79061
                     /locus_tag="ACGI3L_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFG9196155.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            79183..79938
                     /locus_tag="ACGI3L_000425"
     CDS             79183..79938
                     /locus_tag="ACGI3L_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9196156.1"
                     /translation="MKKYNISENGALIKNDSIESKSESVKVVQISDTQIGSFYSTKNL
                     KKVANKINTLNPDIIVFTGDLIDYSNKNPSVDEITTILSSMNARLGKFSVFGNHDYMY
                     KLPRYYRQIMKNSNFNLLVNENKKIKLKDDKYINILGVDEILNGNPNIKYLESQIDNK
                     SFNLLLAHEPDLVDMLSKDTMNLVLSGHSHGGQIRLPIKGALVTPPYGRKYTKGFYDI
                     NGNHLYVSSGLGSTKLPFRFFNIPEIIEFNIII"
     gene            complement(80223..80957)
                     /locus_tag="ACGI3L_000426"
     CDS             complement(80223..80957)
                     /locus_tag="ACGI3L_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFG9196157.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            81082..81798
                     /locus_tag="ACGI3L_000427"
     CDS             81082..81798
                     /locus_tag="ACGI3L_000427"
                     /EC_number="3.4.17.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9196158.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            81932..82624
                     /locus_tag="ACGI3L_000428"
     CDS             81932..82624
                     /locus_tag="ACGI3L_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196159.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            82614..83795
                     /locus_tag="ACGI3L_000429"
     CDS             82614..83795
                     /locus_tag="ACGI3L_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9196160.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            84077..84532
                     /locus_tag="ACGI3L_000430"
     CDS             84077..84532
                     /locus_tag="ACGI3L_000430"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFG9196161.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            84522..85247
                     /locus_tag="ACGI3L_000431"
     CDS             84522..85247
                     /locus_tag="ACGI3L_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 dependent-methionine synthase
                     activation domain-containing protein"
                     /protein_id="HFG9196162.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            85219..87600
                     /locus_tag="ACGI3L_000432"
     CDS             85219..87600
                     /locus_tag="ACGI3L_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HFG9196163.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(87805..89034)
                     /locus_tag="ACGI3L_000433"
     CDS             complement(87805..89034)
                     /locus_tag="ACGI3L_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFG9196164.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            89635..90549
                     /locus_tag="ACGI3L_000434"
     CDS             89635..90549
                     /locus_tag="ACGI3L_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9196165.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            90573..91208
                     /locus_tag="ACGI3L_000435"
     CDS             90573..91208
                     /locus_tag="ACGI3L_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HFG9196166.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            91584..92300
                     /gene="pyrF"
                     /locus_tag="ACGI3L_000436"
     CDS             91584..92300
                     /gene="pyrF"
                     /locus_tag="ACGI3L_000436"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFG9196167.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            92326..93369
                     /gene="carA"
                     /locus_tag="ACGI3L_000437"
     CDS             92326..93369
                     /gene="carA"
                     /locus_tag="ACGI3L_000437"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFG9196168.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            93422..>95742
                     /gene="carB"
                     /locus_tag="ACGI3L_000438"
     CDS             93422..>95742
                     /gene="carB"
                     /locus_tag="ACGI3L_000438"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HFG9196169.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIM"
BASE COUNT        38059 a        10179 c        16950 g        30554 t
ORIGIN      
        1 tgtattttta atggtacgat gtttttaaaa aaggtattaa aacttactga agttaagtca
       61 ccttttatta attgtagggt tttgtcccat aaagaaacta tatccataat ataaacctcc
      121 gaacagaata attaatattt tccacaaagt tattaacaga aaagcaaaaa tatatataaa
      181 ttttacagaa taactaaatt tatggataat ggtgttgata aattaataat agtataaatt
      241 attaaaaaaa tatgaaaaga tataaacaat atgtagataa agttataaat aacataaaca
      301 tacaataaat ggtgattata actagagtat tgtcagtaat cttaaaagtt atacacaaaa
      361 gtatccacaa gctgtgaata atttctaata agttgataac atttatgcac attatcaaca
      421 agtatattta taatatcaaa atatatgtca aacttcaatg atttgtaact aatttatcca
      481 caatattaac taattgttga taaaaatata aacatgttaa aattacttta tttgtgtata
      541 taattgaaaa aaataattta gaataaaatt aaatagattt ttactagtat tttcaataaa
      601 aaaaatacat aatatatata tggtagattt tgtgatataa gcgtcccaaa aactcgttga
      661 caacagtagt aaaagtattt ataattatat gtgttatgtt tactttgagg gtaaagttat
      721 tatttttata aacggaaaat aaaatctgaa aggcggtgca aaataatgag taaaagaact
      781 tatcaaccaa aaaagagaca aagaagtaaa gaacatggtt tcagaaaaag aatgaagacg
      841 tctaacggaa gaaacgtgtt aaagagaaga agagctaaag gaagaaatag attaactcat
      901 taattacaaa agggccgctg caaaggtggc ctttttgtgt aaataattac aattcatagc
      961 tgtgtttatg gaggttaact atggacttta ataggactaa agggttgaaa aaagactctg
     1021 attttagaaa agtatataaa cacggcaaat cttttgcaaa caaatattta gtaatatata
     1081 tacttaaaaa taaatcagat tatagtagag taggtatttc tgtttcaaaa aaagtaggaa
     1141 aagctattac taggaataga gtaagaagat taataaaaga agcctacaga ttaaatattg
     1201 atgaaaaaat taagcctgga tatgatatag tatttatagc aagggtatct agtaaggatg
     1261 ctacttttaa agacatagac aagtctataa aaaatttagt taaaagaacg gatatttcta
     1321 tttaattgta tgctataaat atggaggtta atgactttga ataaaataat ttatatatta
     1381 aaggaaataa gtaagtattt atcgaattta tgtatttatt tagtgagatt ttatcaaaag
     1441 tatatatctc ccttaaaggg acctacctgt agattttatc caacttgctc acaatattca
     1501 atagaggcgt ttaagaaata tggatttgta aaaggtatgt atttaacgat aagaagaatt
     1561 ttaaaatgtc atccttttca tccaggaggt tacgaccctc taaaataaaa gagagtaact
     1621 attaggaggt ataaaaaaat tgaatataat aggaaatttc ttaggattga ttcttaaggt
     1681 aatatttgaa tttgttaatc attatggtat ttctataata ctttttacga tacttgtaaa
     1741 gattatttta ttaccattaa caattaagca gactaagtca acaaaggcaa tgcaagatat
     1801 acaacctcgt ataaaagaga tacaagaaaa atataaaaat aagccagaaa aacaaaatga
     1861 agaaattgtt aagttatatg gagaagctaa aattaatcca ctatctggtt gtttaccttt
     1921 attaatacag tttcctatat taataggatt atttagcgtt ttgagagaac cagttgctca
     1981 tggcgttttt gcaaacaaag ctgcattttt agcagctgac aatgggtttt tatggataaa
     2041 aagcttaaca tcaccagatt atgtattagc agtattttca ggagcaagtg catatgtcat
     2101 gcaaaaagta atgacaccaa aagatcagtt acaaggctct atgaaagtaa tgacatatgt
     2161 aatggcaggt atgtctttct attggggatt tatattccca gcaggactta cattgtactg
     2221 gacagtaagt aacttattct caatagctca atattactta ataatgaatc ctttaaaagc
     2281 taaactggct gctaactcta aggaggaaaa agttaatgag aaaaagccta aaattaataa
     2341 aaagtaagag taaagaggaa gctataagta aagctatagc agagttgaat ttaaaagcag
     2401 aggatataga agtagaaata cttgaaaatc caagtaaagg gtttttaggt tttataggtg
     2461 ctaaagatgg tacttatgaa atttttgtta tcgagaggga agtagatgta gctaaaaatt
     2521 ttatagaggt aatgttgaaa aatgcaaatg ttgatgccaa agtcaatgta tctcaaaaag
     2581 ataatttaat catggttgat attgaaggca aagaagctgc aagtttaatt ggtagaagag
     2641 gggaaacttt agattctatt caatttttga ctggattagc tcttaataaa ataaataaag
     2701 attctcatac aagagtactt gtagatatag aaaattatag atcaaaacga gaagaatctt
     2761 taataagata tgctaataaa gttgctagag aagtagcgaa aacaagaaaa actaaaaaat
     2821 tagattatat gaatccatat gagagaagaa taatacattc agctcttcaa aatgacaaat
     2881 atgtaattac atatagtgaa ggaaccgatc catatagaag attagtaatt gagtgtaaaa
     2941 gataaagtca acctcctaaa cattaggggg ttttattttt taatattatt aaatcattaa
     3001 tgattggtta aatgtaaatc tatatgtaaa aaattatgaa ttaagaggtg ataaatttgt
     3061 ttatagatga tacaattgca gcaatagcta cagcacctgg agaaggtggt ataggtatac
     3121 ttagaataag tggagaaaaa gctttgaagg ttgcagaaga aatctttaaa tctatgtctg
     3181 gaaagagtat tgaagaatac aataagagaa cattaatata tggaaatata gtggataatg
     3241 aaaatataat tgatgaagtt ttattggcat atatgaaagg accaaattcc tatacaggag
     3301 aagatgttat agaaattaat tgccatggtg gatttatttc ggtaaagaag atattagaat
     3361 taatactatc aaaagatgtt agattagcag aggctggtga gtttactaaa agagcattct
     3421 taaatggaag aatagattta tctcaagcag aggctgtaat tgatgttata aaagccaaaa
     3481 ctgatatagc tcatgaagtt gctcaaaatc aattagaagg ttctttatca aagaagataa
     3541 gagaattgag agataaagtc actgagatat tagctcatgt agaagttgct atagattatc
     3601 ctgaggaaga tattgagcat ataacatatc aaactcttaa agaaaaaact gatgaactta
     3661 aaaaagacat taaaaaatta tatgatacag ctgaaagtgg aaaaatactt agagaaggct
     3721 taaagacggt aattgttggg aaaccaaatg taggtaaatc ttcactactt aattctattt
     3781 taggagagaa tagagcaata gttactgata taccaggaac tactagagat gttatagaag
     3841 agtttgtaaa cataaaaggt atacctttaa aaattgttga cacagcaggt ataagagata
     3901 ctgatgatat tgttgaaaaa ataggtgttg aaaagtctaa agaatcattt actagtgcag
     3961 atttgatagt aatggtttta gatgcatcta gaaagttgtc agaagaagat atagagatat
     4021 tagaaaaact taaggataaa caaacaatag tgctgttaaa taagaatgat ttgaaacaag
     4081 agattgaaga agaaaaaata cttaaatatg tagaaaataa tagtataata aaaatatcag
     4141 ctttacaaca agaaggaata gaagaattgc aagataaaat agagtctatg gtatataaag
     4201 gtagtatcaa aaataattct agtttagtag taacaaattc aagacataaa gatgcactta
     4261 gtaaagcata taaatctgca acagatgctt taattgcttt ggaacaaagt atgccatttg
     4321 actttgtaga agtcgattta aaaaatatat gggactatct tggatatatt aatggtgata
     4381 cagtaacaga ggatttacta gataatatat tccataattt ctgtattggt aagtaatgta
     4441 caaaagtaaa cttgttttta ttatagagat ttttaaaaaa tttgaagtgt ttctcatgaa
     4501 acattaattt tgaaaagaaa ggaattataa atgataaagt ttgaagcagg aaaatatgat
     4561 gttatagtag tcggagcagg acatgctgga tgtgaagctg ctttggctac tgcaagaatg
     4621 ggatataaaa ctttgataat aacaatgtct ttggattcca tagcattaat gccttgtaat
     4681 ccatcaattg gagggactgg taaaggtcaa ttagttaaag aaatagatgc cttaggtggt
     4741 cagatgggat taaatataga caagacatat atacaaagta gaatgttaaa tactgccaaa
     4801 ggtccagcgg tacactcttt aagagcacaa gcagataaat ttaaatatca tgaagaaatg
     4861 aaaaagacat tagaagatga accaaatctt gatatagcta tggatgaagt tgtagaaata
     4921 cttcatgaag gaaatgttgt aataggagtt ggaactaaac taggatgttc atttaaatct
     4981 aaagctgtaa tattggccac tggagtttat ctgaactcaa agatatatat gggtgaagtt
     5041 gcattttatg aaggtcctaa tgcattgggg tatgcaaaat atcttacaga tagcttagtt
     5101 gagcttggcc ttagaatgag aagatttaag acgggaactc cagcaagagt tcatagagat
     5161 agtatagact tctctgtaat gtctttacaa gagggtgatg aaaaagtaac tccattctca
     5221 tttatgaatg aaaatataga aaaaaaacaa gaaccttgtt atttaacaag aactacagaa
     5281 gaaactcaaa aagttatact ggataattta aaaaggtctg ctatgtatag tggagtaata
     5341 gaaagtactg gtccaagata ctgtccttct atagaagata aagtagtaag atttagtgat
     5401 aaaacatcac atcaattatt tatagaacca gaagggttaa atactaaaga aatgtatata
     5461 caaggaattt caactagttt accttttgaa gttcaattag atatgtacaa aactataaag
     5521 ggacttgaaa attgtaagat aatgagacct gcatatgcta ttgaatatga ttgtgttgac
     5581 ccaactcaac taaaaataag tttggaaata aagggtgttg agaacttatt tagtgcaggg
     5641 caatttaatg gaacttctgg atacgaggaa gcagcagctc aagggcttat ggctggtata
     5701 aatgcagtta gaaagataga aggaaaagag ccatttgtat tagaccgttc agaagcttat
     5761 ataggtgtct tattagatga ccttgttact aaaggaacta acgagcctta cagaatgatg
     5821 acatcaagag cagaatatcg actatattta agacaagata atgcagatat gagattaact
     5881 caaaaaggtt atgatatagg attagttaaa aaagatagat atgaaaggtt cctaaataaa
     5941 aaggctgctg tagagaaaga atttgaaaga ctaaaaaatg aaagagttac accaaaagaa
     6001 gtaaatagtt tgttagaaga aaaaggagca acaccaataa aggttggaat atctctatat
     6061 gaatttttaa agagaccaga ggttacttac gaattgcttg aagaattagg gaaaggcgct
     6121 ggagaagatg tttcaagaga agttaaagaa cagtgtgtaa taataactaa atatgaaggt
     6181 tatatagaga aacaattgaa acaaatagac caatttaaaa aacttgagaa taaaaagctg
     6241 gatgagaaaa taaattattc atctatagaa ggtcttagat tagaggctag acagaaacta
     6301 gatgatataa aacctatttc aatagggcaa gcatctcgta tatctggtgt ttctccagct
     6361 gatatatcag ttttacttat atacctagaa caaatcagaa gaactagagg tggcaaaggt
     6421 gaataatata gaacttctga aaaacgggat tgaaggtttt aatatagata cgaatgacag
     6481 tatgttagaa aaatttaaaa tctatagaga gatattagtt gactggaata aaaagatgaa
     6541 tcttactgga atagaagatg aaaaagaagt gtatataaaa cattttttag actctatttc
     6601 agctgtaaag aatggatata taaaaaatgg gatgtctata atagatgttg gtacaggtgc
     6661 tggttttcct ggaataccat tgaaaatatg tttagatagc ttagaactta ctttgttaga
     6721 ttcgttaaat aaaagaataa actttttaga ggaagttagt agagtactag agttagataa
     6781 tattacattt atacatggaa gagctgaaga ttttggtaaa gatgaagact atagggaaaa
     6841 atatgatgtt gctacggcaa gagctgttgc tggattaccg attcttatgg aattttgtgt
     6901 accatttgta aaagttggag ggtattttat ttgcttaaaa ggtccgaatg ctaatttaga
     6961 gctagaagaa tcacaaaagg ctattgatgt tttaggattg gagtatattg aaaaaataga
     7021 tgtagagtta ccagaggtag atttaaatca taatatatta gtttttaaaa aagtgatgga
     7081 aacaccagtt aagtacccta gaaaagctgg taaaccagcc aaaaatccta ttaagtaatg
     7141 aaaaatttat tattggtaag cttaattatt tctcaggaaa taattaagct tactgtaaaa
     7201 aaacaaaaat aaaggaatta ttaaagtaga tgcagaaata aatttgtatg tacatataga
     7261 gaacaaaaat aatttatatc taaaataaga gaggtatgtt atggaagata aaagagttat
     7321 ggagatacct atagaagatg tagttccaaa tccatatcaa ccaagaaaaa tattttcaca
     7381 agtttcattg gaggaattga gcaattctat aaaggtatat ggtataattc aacctataac
     7441 agttagagca aaagatggca aatatgaact aattgcagga gaaagaagat taagagcagc
     7501 taaattagca gagcttaaaa ccataccagc aattataaat aatatgaacg atgaatcttc
     7561 tgctgttcta gcgttattag aaaatttgca acgagaagac ttaaatttca ttgaagaagc
     7621 aattggttat gaaaacttaa taaaagaaca tgcttttact caacagcaat tagcagaaaa
     7681 attgggcaaa aatcaatcta ctgtagcaaa taagcttaga atattaaagc ttccaaacga
     7741 tataaaaatg aagctaatag agaataattt aacagaaaga catgctagag catttcttaa
     7801 actaccaagt gaagatttaa tgcaaagtgt gttagacaaa gtcataaaaa atgaattgac
     7861 tgttaaaaaa acagaaaaat tgatacaaga tgtattagaa gaaactaaag ttcaagaaga
     7921 gcctgataaa aaacagaata taaagggtgc tatgagtata agaatttaca taaatactat
     7981 aaagcaggcc tttgatgcta tatcaaatac aggaattgat gctaagtata atgaaataga
     8041 taagggagat tatatggaag ttgttgtaaa aatccctaaa aaatagagat tactgcttac
     8101 cagtaatctt tttttgtaat ataagccttg taatataaat tgatttatag acattattta
     8161 tacttaaaaa acacctattc aacatttaaa attaatttaa ttcttaaagg ggggaacatc
     8221 atgggcaaag ttatagctgt attcaatcaa aagggtggag tcgggaaaac tacaacaaat
     8281 gtaaatttaa gtgctagctt aggaactttg ggaaagaaaa tattagtatt agatttagac
     8341 ccacaaggaa atacaactag tggatatggt attaataaaa acgaagtaga aaatacaatc
     8401 tatgaaatta tgttagatgg gttacatatt aaagaagcaa taataagtac tgaatttgag
     8461 aatgtagatg tagttccatc agctactgaa ctatcaggtg cagagataga gcttacatct
     8521 aaaactaata gagagtatat tttaaaaaat tccataaaag cggtaataga tgaatatgat
     8581 tatatatttt tagattgtcc accctcactg gggatgctta caataaattg tttaactgct
     8641 gtagatagtg ttttaattcc aatacaatgt gaatattatg ctttagaagg tgttagtcaa
     8701 ttaatggaga ctataaaatt agtaaaatca agattaaatg ctgatataga aattcaaggt
     8761 gttgttttaa gtatgtttga tggaagagct aatttatcaa tacaagtagt tgaagaagtt
     8821 aagaaatact ttaaaggtag tgtatataca actttaattc caagaaatgt aagacttgca
     8881 gaagctccaa gtcatggaaa acctgtaatt tattatgata aaagatgtag agggtctgta
     8941 gcttatttgg agctagcaga agaatttata gatttagaag aggaggaatg gtagtatgga
     9001 gaataagtct aaaagaagta atagattagg tagaggtctt agtgcattga taccagaaat
     9061 taaaggagaa acttcagaaa aagaaatagt caacatagat atagacaaaa tatatccaaa
     9121 cgaagttcaa cctagaaagc aatttgatga agaaaagata aaagtattgt cggattctat
     9181 aaaaaattat ggtgttttac agccaatagt ggttaaaatg gatgaaaata ataaatatat
     9241 gataatagct ggagaaagaa gatttagagc atcaaaactt gcaaataaaa atcaaatacc
     9301 tgctataatt aaagatatag atatgaaaga tataatggag atagccttaa ttgaaaactt
     9361 acagagggaa gatttaaatt caatagaaga ggctctagca tataagagtt taatagagca
     9421 ttacaatgta actcaggaag aaatatcaga agctgttggg aagagtagac ctcatataac
     9481 taatacacta agacttttaa atcttggaca agatgttata gaaatgatag acagtggtag
     9541 aatcacagca ggccatggta aggctttatt gagaattgca gataaagatt tgcaacttca
     9601 aatagcgaaa aaaatagaag aagaagaact ttctgtaaga gaagtcgaaa atatagctaa
     9661 aaaaatatct gaaaataaac aagaagaacc taaaaaatct aaacctaagg atgtatttat
     9721 tttagatgtt gaagataaac ttagaaatat atttggaaca aaggtgaata tttctaaagg
     9781 aaagaaaaaa ggtaaaatag agatagaata ctataatgat gatgatttaa atagtattgt
     9841 atcaatgctt cttgaataga acaaaaatat aaaacagaga ggaagattgt tatgatttat
     9901 ttagataatg ctgcaactac atatccaaaa ccagaaagag tgtataatgc tgttttagat
     9961 tgtatgaaaa attattgtgc aaatccaggt agagcaggcc ataaacttgc tatgagagct
    10021 gctagggaga tatatgatac aagagagaat atagctaagt tgttcaatgt aagtaatcct
    10081 atgaatatag tatttacatc taatgcaaca gattctttaa atttagcgat aaaaggtgta
    10141 ttacaagaag gagaccatgt aataacaacg tctatggagc ataattcagt aataagacct
    10201 ataaaagcat tggaaaaaag gggtattgaa aatactgtag taaaatgcga ttatgaggga
    10261 tttttagatt atgaagattt agaaaaatca ataaagagta atactaaact gattgtaaca
    10321 acacatgcgt ctaatgtatg tggaacttta atagatataa aaaaagttgg agaaatagct
    10381 aaaaaacata atatactatt tttagtagat gcatcacaaa cagcaggtgt ttatgatata
    10441 gacgtaaatg aatgtaatat agatatgttg gcaatgccag gtcataaatg cttatttgga
    10501 cctcaaggaa caggtatatt atatgtaaga gaagggttga acttaaatat attaaaagaa
    10561 ggtggaacag gtagtaaatc agaagaaata gttcaaccag agttattccc agataaatat
    10621 gaatcaggaa ctcataatac tccaggtata gcaggtctta accaaggtat actatttata
    10681 tttgaaagag gaatcaacaa tataagacaa catgaagaag aattatgtca atatatgata
    10741 gacaaattag aggaagtacc agatataaag atatatggac caaaggacag taaaaaaaga
    10801 gcatcagtaa tagctctaaa tataggagat atggattctg gagaggttac tttcttatta
    10861 gatagtgatt ataatatagc gactagatca ggaatacatt gttcaccact agcacatacc
    10921 actttaggta ctttaaaaca aggtgcagta aggtttagta taggatattt caacacaaaa
    10981 gatgagatag ataaagcagt ggaagctttg aaaaaaattt caaaaaataa atagcatgag
    11041 atttaataat atagaaataa aaaaagggga tatttcaaaa taaaaatttg aatcatctcc
    11101 ttttttgtac aaaaaagaaa aggggttcct aagaacctct aatctatttg ataatagttt
    11161 caagaaatta ctttaagtaa tctccttctt caagaactat atgaccactt tcgtaattag
    11221 aaccatcaac agtaattttt atttgttcaa cattcatatt ttttatgtaa gtacgagcaa
    11281 ctgaatcaag cattaaagtt tctgcatcac tacctaagtt tgactttgta aagtcagagc
    11341 taacatctaa tataccagtt tttacaccat caatgtcttt tgtagtaaat gaatttaatt
    11401 ttgcagattc tggaacaact ttaagttttt gaagttcttc aaataaagtg ttctcatcaa
    11461 ttttatttaa atcaacttta ttttcaatta aatctgtctt atctacatca aaagagtaaa
    11521 tagtagctga ttgagtttta gtttcttctt ttggagtagg tttagctttg ttattaggaa
    11581 cctctttttc agtattgttt tcttcttttg gttgctcaac atttgtattg ctcttagttt
    11641 cttttttaga tgaatcactt ccattttgag cattagtaca accaactgcg aatatagata
    11701 tagataatat acttaacact aacattattt tcttattttt cataaaaatt tctcctctct
    11761 taaaaactat tcttatatat aattatagtc gttatgagca aatatatgaa tacaaaatag
    11821 taacaaattt aaaaaatgat ttatttaaat taataaaact caaaataaac taaattttag
    11881 tcatttttat gggaaatcat ttaatgtaca gtgaaaatat tgtaaaataa aagtagtgtt
    11941 tttaaaataa atataagtta taattatatt ataaaaaaat gtcttcaaaa ggtgggaata
    12001 gtatggaaat tttgagctta ggagaaaaga ttaaaaaatt aagaaaagaa aaaaacatga
    12061 cattaaaaga attagctgga gataggataa cagcagcaca aataagccat atagagaggg
    12121 ataaatctca tactagttat gaactgttgg aatatctagg cgataagcta gatgtaagtg
    12181 tagaatactt attagagacc aaggaaatgc aatcaaaaaa gataactgat aatttaatac
    12241 tacagagcga aatttatata aaagaaaatg aattaaacaa ggctgaggac caaataaaag
    12301 aagttttaga tatatgtaag agatacgatt taatggagaa ctatggcaga tgtaattttt
    12361 taatggctaa tattaatttg aaaaaatcta attataatga tgctatagaa aactttgaaa
    12421 aggcattgta cttctttata aaaaatagtg atagtgaaaa tatacttaag tgttatttaa
    12481 acatagggaa aatatatatg caggaagact tttataaagg tgctataagc cactttaatt
    12541 ttgcagagga aattttgtca gagaataaat ttgaggatgt taacatacac aaggaactat
    12601 atagtaagat ggcatattgt tacataaaac tagataatcc aaatatgtca ttgaagtaca
    12661 tagaaaagat aaatgaaata gataatagaa atgatagaaa agaagatgtc gatattttgg
    12721 tgttaaaagc aaataatatg cttgagattg gaaaatatga agaatcaaga gattacttta
    12781 aaaaagcact aaaaatactt gagagtgagg ataataaaac tggattagca aatgtgtatt
    12841 taacaatttg tgatgtttac agaaaaatag gtgaaacaga tagagtactt gaatattcac
    12901 aaaaggtata tgacataaag aaaaatgatg aagatgaata catgatgtca ggattattta
    12961 agataataga agcatatata gataaagaag attatgattt agctagaaaa tattgtaaga
    13021 tagccttagc ttcatcaata aaaaataaaa ataaattcaa tgaatataaa gcattgagat
    13081 tctatgctaa tatgtataaa aatcagaatg aagtaactct tgcaattgaa tatctgatta
    13141 aatgcataaa aatagtatca gatttaggca acaatagaat attggccaat ttatatatag
    13201 acttaggtca attatattca aatatatcaa aagaaaaaga gttagaatat tatcaaaaag
    13261 gtgtatttat gtacaaaaat ttagaaataa tgtagggtaa ataaacctat aagggtatag
    13321 aaacaatcta taacaagcaa gataatatct atgataaaat ataaattgta tgaatatttt
    13381 taaggagatg aatcagacaa tgagtataaa aatagatgcg agagggcttg cttgtcctaa
    13441 accagttata aatacaaaaa gagaattgga taacctagaa gaaggtgttg tagttacaat
    13501 agtcgataat gaaacagcta aggagaatat attaaaactt gctaaatctt taagttgtga
    13561 agcaaatatt gttgacgaaa aagagaattt tatatctata gaaattagaa aaggtaaaaa
    13621 tatactagat aaacaaaatg ttgtagataa taaagaaagt gaattagaca atacatgtat
    13681 atttatatct tcagataaga tgggacttgg aaatgacgaa ttaggaaaag tgttaataaa
    13741 aggatttata tatacattaa cagaatctaa accttatcct aagtatgtac ttttagttaa
    13801 tggaggagta aaattaagtg ctgaaaatga agaaaccata gaaaatctaa aaatacttga
    13861 gaatatgggt gtagaagttt tatcttgtgg tacttgttta gattattata atttaaaaga
    13921 caaattacaa gtaggtacag ttacaaatat gtatactata gttgagacat taaagaatgc
    13981 atcaaatacc atttctatat aatgtatgtt tgtttaataa tataaaatta ataataaaga
    14041 ttaactcaaa tagatagtca gaaaggatta agtaatgaat caaatgtata tagtgtcatt
    14101 taattcgaca catcatgcga taagatcaga aaagttattt ggtgaaaata gtctaaaagt
    14161 aatggctctt ccaacaccaa gagaaataac agcaagttgt ggaatatcaa ttaaattttc
    14221 ttttgaagat atggaaaaga taaaaactat tttagttgaa aataatgtag atataaaagg
    14281 aatttattgt ataagtaaat tagaaaatgg ctcaaaagaa gtagagaagt tagattagga
    14341 ggctaattat ttatgccaat ggatttaaaa ataggtgata ttgttgaatt aaaaaagcaa
    14401 catgcatgtg ggtgtaaaga gtttgaaatc ataagaacgg gaatggatat aaagataaaa
    14461 tgtactaaat gttcaaggct aataatgctt gatagagaga ccttagaaaa gagagtaaaa
    14521 aagctaataa aaaagtgata aaaatttaac acttaaaaaa tgtcaaatac cgtatattaa
    14581 tatccaaaat tttggtataa taagaattga agaaaacatt ttcatggggg tgctttaatt
    14641 atggcagtta aatatgcaaa aagaatgcaa ggattacaag gatcagaaat acgtgagctt
    14701 ttaaaactta ctcaacaacc acaaataata tcttttgctg gtggaatgcc ggctccagag
    14761 ttatttccag ttgaggaaat gaaaaaagta tcagttgcag tgcttgaaga aaatggaaga
    14821 tcagctatgc aatatactac aacagaagga tatgaaccat taagagaaaa aatagcagct
    14881 agaatgaatg ataaaaacaa aactaatgta aacaaagatg atatattagt tacaagtggt
    14941 tctcaacaag gtctagattt tgcaggaaaa gtatttattg atgagggtga tgtaatttta
    15001 tgtgaaagtc catcttacat aggagctata aacgcattta aatcttatca acctaaattc
    15061 atagatgttc caacagattc tgatggaatg ataatggaag aattagaaaa gatactagaa
    15121 acaactgata gaataaaaat gatttatgta atacctgact tccaaaatcc aacaggaaga
    15181 acttggccac ttgaaagacg taaaaaattc atggaaatag taaataaatt tgaaatacca
    15241 gtaatagaag ataatccata tggagattta agatttgaag gagagacttt accatcttta
    15301 aaatcaatgg atacaaaagg attagtaata ttcttaggaa ctttctctaa aatattctgc
    15361 ccaggataca gattaggatg gacttgtgct tctccagaaa ttttatctaa gtttaacttt
    15421 gcaaaacaag gtgcagactt acaagcatca actatatctc aaatggaagt aagcaaattt
    15481 atggatatgt atgacctaga tgcacatgtt gacaaaataa aagcagttta tgttaaacgt
    15541 agagatgtaa tgcttaagac tatggaagaa gagttcccag aaggattagt atttactcat
    15601 ccagaaggtg gattatttac atgggtagag cttccaagta atttaaatgc taaagaatta
    15661 atgccaaaat gtttagataa gaatgttgct tatgttgctg gaggaggatt cttccctaat
    15721 ggtggtagag aaaatacttt cagacttaac tattcaaata tgccagaaga aaaaataata
    15781 gaaggtataa aaaatatagc agctgtatta aaagaagcta tgggtgtaga agcttaatta
    15841 aaaataataa cttatatata atacaaggga tggttgttgc catcccttgt ttgtttgaaa
    15901 agtatataat tcaccttata ctaaactttg tccaaaattt aaattgacag aaataagaat
    15961 aaatgataaa atgtgtaggt atgagatttt agtctcattt ctctgctcta agagtgtaga
    16021 gccgttaagt ccaaagggag gtgaattata gtgagaaatt atgaattagt ttatgtggta
    16081 aagccaaact ctgatgaaga agtaagagag gctatactaa acaaagttaa ggaagttgtt
    16141 gcaactgacg gagaaatagt taaagttgat acttggggaa ctaaaaaatt agcttatcca
    16201 atagctaagt ttacagaagg tttctatgta ttagttaact tcaaatcagc agtagacgtt
    16261 cctaaagaga tagacagaaa cttaaagata aatgaaaacg taataagaca catgatagtt
    16321 gttgcttaat aactggtttt attataaaaa ataggtggtg tttttatgaa tcaagttgta
    16381 ttagtgggaa ggttgactag agaccctgaa ttaagataca tcccaggtac aggaacacca
    16441 gtggcatcct ttacaatagc cattgataga gactatgtaa aaaaagatgg atctaaagaa
    16501 actgatttta tacctgttga agtaatgggt aaatctgctg aattttgtgc taactacata
    16561 actaaaggta gattagtagc acttcaagga tctataagag tagacaatta tcagacacaa
    16621 tcaggtgaaa agagaacttt tacaaaagta agtactagat cagtacaagc tttggatagt
    16681 aagaataaat cggaaaattc atatagagag agtgctccag cttttgagcc aagctttgaa
    16741 cctcaaggtt tagacccaca aggtttccaa gctatagatg atgacgatat accattttaa
    16801 aaaggaggga aaaaagtcat gatgaataaa aaaagacgta agaaaaaaag agtttgtcaa
    16861 ttttgtgctg acaaaaacgc taaaatagat tacaaaagta ctcaaagatt acaaaagtat
    16921 ataactgaaa gaggaaagat attaccaaga agaatatctg gaacttgtgc taagcatcaa
    16981 agagaattaa cagttgctat aaaaagagcg agaaatatag cacttttacc atatacatta
    17041 gactaaaaaa atgagccttg tgctcatttt ttattatatg tatttatata tctaaatgag
    17101 gcgagctata aagctcgttt ttttgtttat atacttaaat atattattat ttatgatata
    17161 atattatata ttaaggaggg ttgtaaacgt gaaaatagat aaaggttctg agataacgag
    17221 aaacataaag ataatagaat ggatgaaaac agaaatatta atgagtgtaa gtgatttgtt
    17281 taatttattg tttaaagggg taaaaccatt agatgaagca attcaagata ctttagcaaa
    17341 tataataatg ataacatatc tcttagcaaa gagattagga attagtttta gagatgtgga
    17401 ttataaagtc aaggaaaaaa taaaaattgg tatagatgag gaccatagcg ttgaaagatg
    17461 gtatggagat ttatctaatt taaaaaaaca tatggataat agggagtgat attaaattga
    17521 ataataaaat tagactatct aaggcaatgt ctataatagt tttagctata ataatcgctt
    17581 tagtaatagc ctatattcca atgctaggaa tatttagtat gttagcagct gttccatatg
    17641 taattatagg tgctattact gatagaaagt attctcttat atctattttg gttacatttt
    17701 gtgtactgat tctatttgca gacatttctt atgcattaaa tatatgtata atgtattctt
    17761 taccaggtat agtaatagga aagatgctaa agagaagctt tgaacaagag gacagtaata
    17821 aattcgaacc gatatatggt ggaaccataa tatttgtact ttcaatgctt gtatattttt
    17881 ttgtattaaa gacattttta aatgtgaatc tattagatga agtttctaag atgatatcag
    17941 aaattgtaaa tattcaaaaa aatagttttt ctgcaactga acttaaagtg tttgataaaa
    18001 tgaagccaga tgagattgta agttatttta caaatatgct accaatgatg ttatttttac
    18061 aagggttgtt atcagcgttt gtcacatatt atttgagtgt attttttata aaaaggatta
    18121 caaagatgaa tataagattt cctaagtttg ctgattttta tttaccggga aatgctatac
    18181 tcacaacttt cttactttat ttattagtct tatttattca aattattggt tcaaaattat
    18241 atacagaatt aataatgact aatttacagc tagtttttaa tttaatgttt gtaattcaag
    18301 gtatagcagt ttgcatttat ttcttaaaga aatggataag acagggacca aataaaatta
    18361 tgtttttttc agggataatt ttatgtttat ttggatttat gggaatatct tttgttggta
    18421 tggtagatag tataattgac tttagaaagg taagaagcta taaatccact taggaggata
    18481 gaaatgagta ataaacaaac ctttaaatta aatatgccag aaataaattt atatataatt
    18541 gttattggta tttctagtat aattttgctt tattacaact tgtatgtagg gtgtttattt
    18601 ttctgtattt ttgtatatat ggtttttcac aattggagaa ctactaatat tagacgtcat
    18661 gaatggacag agtatattca aaatttatct ttagatatag atgaaacaac taaaaaagcc
    18721 ataataaatc ttccaatacc attatgtatt ttagaatttg atggaaatat atcctggtat
    18781 aatggaaagt tttatgatat gattggtcaa aaagatttac ttgataaaaa tatagaggat
    18841 atagttaaaa atcttaattt aagaaaagta ttaaatgaaa ataaagagat gtacacagaa
    18901 ataaactata aagaaaaaga atatacaata atttataatg ttataaaaaa tgatcaagaa
    18961 aaaaatccta aatatttgat gatattatac tggatagaca agactgaata tttaaaagta
    19021 aaacaaaatt atgatgatga aaaaaatgca atgatgctaa tacaagtaga tggatatgat
    19081 gaagtattaa aaagtgcagc agaagataag agagctttaa ttaatgttga agtagagaaa
    19141 atactttctg ctttagaatt aaattcaaat ggtgcattga gaagaacttc aaaagacaaa
    19201 ttcttcttgg taatgcataa aaaagagtta aaaaaattgg aagctgagaa gttttctatt
    19261 ttagatacaa taagacatat tgattatgga aataatcttc ctgttactat aagtatagga
    19321 attggtatag atggagatac attaaatgag aacctaaaac ttgctacggg tgctctcgat
    19381 ttagcacttg gtagaggtgg tgaccaggct gttgtaaaaa caaaagataa atttgtgttt
    19441 tatggaggaa aatctaaagc tgtagaaaag aaaaccaaag taaaatccag attaataggt
    19501 catgctttaa gagaggttat acaacaaagt gaccaagttt atataatggg acataaatat
    19561 cctgatatgg atgctatggg agcagcagtt ggtgtttatg atatatgtaa atcctgtaac
    19621 aaaactgcaa acatagtttt acaatctgta aatgaatcta tagaaatatt tataaataaa
    19681 ataaatgaaa ataattacta taaaaagttg tttattggaa aagaggaagc tattgacaac
    19741 tgcactaaaa atacattagt tgtagtagtt gatactcata gaccaaatta tactgaatgt
    19801 gaagaactgt taaagctatc agagaaggta gtagttatag accatcatag aagaggtgta
    19861 gagtttataa atgatgcagt gcttttattc catgagatat atgtatcctc aacgtgtgaa
    19921 atggttacag agttagttca gtatatggat gaagatgtaa caataaataa acttacagct
    19981 gaagggcttt tagcaggtat aagtctagat actaaaaact ttgcattcaa aacaggtgtt
    20041 agaacttttg aagctgcttc ttaccttaga aaagttggag cagatactat agaggtaaag
    20101 aaattcttca attctgatgt aaaagatttc ataataaaag ctgaaataat tcaaagtact
    20161 aaaataatta ataatagaat atgtttagca tattcaagta ctgagataga tagtataaat
    20221 gttataatag ctcaaactgc tgatgagtta ttaaatatca aagaagtaga agcttccttt
    20281 gtattaggtg aaaaagatga tactatattt ataagtgcga ggtctttagg acaaataaat
    20341 gtacatgtac ttatggaaaa attaggaggc gggggacaca tagatatagc tggagcacag
    20401 ttaaaaaatg tttctctaaa agaagcttat aagatggtaa ataaaataat agaggagtat
    20461 ttggaggagg aagaatagat gaaagttata ttattaaaag acgtaaaagg aactggtaaa
    20521 aagggagaaa tgaaagaagt aagtgatgga tatgcaagaa atttcttatt tcctaaaaag
    20581 atggctgtgc aagcagatag tgtagcaata aaagaattaa atgaaaagaa taaatctaaa
    20641 gaaataaaag cacaaaaaga gtatgaagaa gcagttttat taggtaagca aatggaagaa
    20701 attaatatag aaatatattc aaaagcagga gaaggtggaa gattatttgg ttcaataact
    20761 tctaaagaaa ttgctgagca attaaagaaa caaaaagaca tagatgtaga taaaagaaaa
    20821 atattattag atgaaccaat aagatcttta ggttcaactt tcgtagaaat aaaaatacat
    20881 caaaaagtaa ctactaaaat aagagtggat gtaaaagaaa aacagtaata actagaggtg
    20941 attaagatgg aagatatgac gagaattcct cctcatagtg tagaatcaga acaatcaata
    21001 ttgggttcta tacttctaga taaagatgct ataataacgg ttacagaaac tataaagcct
    21061 gatgatttct ataaagaggc tcacaaaata atatatgaat gtatgataac tttaagtaat
    21121 aaaggtgagc ctatagactt gataacatta acagaagaac taagaaaaca agggcatctt
    21181 aatgatattg gaggaatcag ttatattaca agtctttcta ctatagtacc gacgacttca
    21241 aatgtaaaat actatgctga tatagtaaaa gaaaagtctg tacttagaaa gcttataaaa
    21301 gcttctaatg aaataataaa tctaggatat agtggagcaa ctaagattga agatgtttta
    21361 gaacaagctg aaaagagtat atttgatata tcacaggaga aaactagtga tgattttaaa
    21421 tctataaact tagttttgat ggatgcctat gatatgatag aaaaattata cactaacaag
    21481 agtgatgtca ctggtataac tactggtttt aaagatttaa acaaaaaaat aaatggtctt
    21541 caaaggactg atttaatatt aattgcagct agaccagcaa tgggtaaaac tgccttttct
    21601 ttaaacttgg ttcaaaatgc agccttaaaa ggtgatgcct ctgtagctgt atttagttta
    21661 gagatgtcta aggaacaatt agtacaacgt atgttatctt cacaatctag tgtagaatta
    21721 aaaaaaataa agactggaac acttaatgat aatgattggc ctagaattat agatgctatg
    21781 gcagtattat cagatgccaa aatacacata gatgatactc ctggtataaa aatatcagaa
    21841 ctaaggtcaa agtgtagaaa gttaaaaata gaaaaaggac tagatttagt gcttattgat
    21901 tatcttcaac ttatggaagg tgaaggtaat aatgaaagca gacaacaaga gatatctaag
    21961 atatcaaggt cactaaaaat attagcaaaa gaattaaact gtcctgtagt agcactatct
    22021 cagttatcac gtgcaccaga acaaagagca gaccatagac ctatgttatc tgatttaaga
    22081 gagtctggag caatagaaca ggatgcagat atagttatgt tcttatacag ggacgaatat
    22141 tatcatgctg attctgagag taaaaatata ggagaagtaa taatagcaaa aaatagacac
    22201 ggtgaaactg gttctgtgga acttgtttgg cttggtgaag ttcaaagatt tggggataag
    22261 ttgagagacc tataatctaa cgaatatcca cagaacgtcc tttctttcta caggaaaaat
    22321 gtggatacat gtcactaaat atgtccaaac attgaaattt agctaaaaaa ctatccacac
    22381 tatccacaga tggcctgttg ataagtgtga ataagtagat aaagcaagct tttggcttgc
    22441 tttatctgtg tataaatatt aattattagg aggaataata tggaaaaaat aagcttaaaa
    22501 tatatatatc ccaatataat taaagtactt gatgaaataa acttatttag agtaattgac
    22561 aataatttaa gagaatctat tgttgtttat gctaataatg tggataatca gtatcatata
    22621 aacatgacta atacaaactt tggaaatata attaacatat gtaaattaga aaaactttta
    22681 gatgtggata aatttatgga aaaagttata aaatatgaaa aagaaataat agagaaagaa
    22741 gagttttcaa aaatagaaga atatatgtta aatattggag aatactaaaa aagttgaaaa
    22801 aaatacgaat gtttgataga ataagtaagt aaagtgttcg agagtatata aaatatagag
    22861 gtgaattaca tgaaaacagt tgcaattgtt ggttctcaat ggggagatga aggtaaaggt
    22921 aaagttatag attatcttgc tactcaagca gatgtagtag taagagggca aggtggaaat
    22981 aatgcaggac atacattagt tgtagaaggt aaaaaatacg cattacatct aattccatct
    23041 ggagttttaa atccaaatac agtgaatata atcggaaatg gaatagtgtt tgaccctaaa
    23101 ggatttttag aagaattgga aatgtttaaa acggataata taagtacaga aaatataaaa
    23161 ataagtgata gagcacatgt catattccca tatcataaag aactagatgc attgtcagaa
    23221 gaagccagag gcgatttaaa gataggtaca acaaaaaaag gtattggacc ttgttatatg
    23281 gataaaacag agagatctgg tattagaata tgtgacttaa tggataaaga taaatttgct
    23341 ataaaattaa aagctcaaat agatgctaaa aatgaaatag ttaaaaatat atatggaaaa
    23401 gaagaattat ttgattttga aactatatat aacgaatatc taggatatgc agagcaaata
    23461 agaaaatatg tggcagatac gtctgttatt gtatatgatg cagtaagagc aggtaaaaaa
    23521 gtattgtttg aaggagcaca agggacttta ttagatttag atttaggaac ttatccattt
    23581 gttacatctt ctcatccaac atctggtgga tttgcaattg gtgcaggtat agggccaaat
    23641 atgataaaag acgttgttgg tatagtaaaa gcatatacta caagagttgg agaaggaccg
    23701 tttgttacag agcaaataaa tgaaactgga gataagataa gagaacaagg acatgaattt
    23761 ggggtaacta ctggtagacc aagaagatgt gggtggtttg atgcagttat agttaagtat
    23821 gcagctagag ttaatggatt gactagtatt tcatttatgt tacttgatgt attaactgga
    23881 tttgataaga taaaagtttg tacgtcttat aaaatgggcg ataagataat aacggatttc
    23941 ccagcttcat tagatgattt agcaaaatgt gaacctgtat atgaagaatt agatggatgg
    24001 aatgaagata taactcaaat agataacttt gatgaccttc cagaaaatgc aaagaaatat
    24061 gtagcaaaaa tagaagaact agttggagta agtgtagata tggtttctgt tggtccaaat
    24121 agagctcaaa ctataataag aagaaatata tttgcttaat attttatcaa ttaaataatt
    24181 taaaatagtt gaagaagagt atctcaagat aatgtttata gttattagag atgctctttt
    24241 atatttgact tacattgatt ttttattaag ttaaagctac ttatacatat tctaactgaa
    24301 attaaagttg aatttatgta gatacatata ggttttttaa aaagaatttt gttgaaaata
    24361 aatggctaaa gatgatttta attatattct aaaaaaagta aaaaaaacta ttgactaaaa
    24421 attatataga cgctataata taacttgtga gtgaaagaaa cgacgaaaaa agtcgaaaaa
    24481 atgtggtcta ttagctcagt cggtagagca cctgactttt aatcagggtg tcccgcgttc
    24541 gagtcgcgga tagatcacca aaatatggct cgttggtcaa gaggttaaga caccgccctt
    24601 tcacggcggt aacaggggtt caattcccct acgagtcacc agtatgggac tatagctcag
    24661 ctgggagagc acctgcctta caagcagggg gtcacaggtt cgagccctgt tagtcccacc
    24721 aaattttgaa ttagagataa atactagatt atatgctggt gtggctcaac ggtagagcag
    24781 ctgacttgta atcagcaggt tgtaggttcg attcctatca ccagctccac aaagtacata
    24841 aattcaaatt aatataattt tctatgttac aggatacttt taagtatctt tttttaattt
    24901 catttttatt gtattaaaaa tgaaattaaa catacaacaa aattttgaat tacttgcaat
    24961 gtgatagttt taaatataaa atttagaatc attctagcat aatattatgt aatatagcaa
    25021 atttaattta tagtatcaat aaatatagac tactaagaat gtaaatgatt tgttagatta
    25081 aggtacatta gatatgtaaa tagaaaaata aaaagtatgt tttaatttat gtgatataag
    25141 ttttaaacag agaagcaagt ttgctcttac ctctctattt aaaaataaaa aaatgttttt
    25201 taagggctat tttatttaaa tctttcccat ctcaaatcat ctccagtaaa ttctaaaatc
    25261 ctaaacttat ctaatattct agagagagtt ctttgagtgt aagtatttcc tatttgagat
    25321 ggtgttaagt tggttgaaat aatgattttt ttaccagcaa caagtcttgt atttacaata
    25381 ttgaagattt ctccactagt aaaagaatta ttaagttcag ttccaaggtc atctattatt
    25441 aataaatcac aatcaaacaa gtttttataa ttatcttcac ttatttgatt atttgtgtct
    25501 cttctaaatt tataatcttc aagaatatct aaaattctaa aagaagtttg atagattaca
    25561 acattgcctt tatctaacaa ttcctttgca atacaattgc acatataggt ctttcctagt
    25621 ccagtagaac cataaaacag tagattttca ctattatcct tcttaaaatc atgaacaaaa
    25681 ttttcgcaga tacttaaatt atttagcata ttttctctag gagatatttc accatcagag
    25741 cctttcttag gagaaaatat attcaagtta aaattcgaaa aattttcctg acttaaaatc
    25801 ctatctaaat tagacatttt ataagcttca tttacaattt cttgtttgag gcaagaacat
    25861 ttttctccat taggtaaaaa tcctttatct ttacaagaaa tacattgaaa ctttatttcc
    25921 aagtaatcaa gaggtatgtt actttcagct aaaagtcttt ctttctttac ttttaaagat
    25981 tctatattct ctttagtctt ctttacaatt tcatctttag acttaggatt taaaagtact
    26041 atcttagcta aactgagacc tattttagaa atttcatcat ctatagattt tatctcaggg
    26101 attctattat atacctcatt ttttctatgt tctaataaga gttcattatc atctcttctc
    26161 ttagcatatt tagcaagtat ttttcttatt ttatcctcat tcatttaatc acctacttaa
    26221 acttttcttt ttgacttttt ttaataatct catcgagctc atcagaggta tactgagtga
    26281 atgtttcgtt gaaattatga aacttagttt ttttgtaagt attgttgttt tgagtagtat
    26341 taatctgctt cttattaata ttctccttaa ctatacgttc ttcctctttt tgctttaaat
    26401 catttaaatt ttttatattt ttttcattcc aatttttaat tataccattt atataagata
    26461 tacttgggtt tgaaatattc ttagacttag aacatgcatt tattatcaaa tctatatcca
    26521 tattaaattt atcaaaccag gtgtccataa gttctttttc tgattttgat ggttgtcttg
    26581 aaaatcccaa ttcattgaaa atcgttttat ataaaatata tcgttcactt cttaccaaaa
    26641 agctttcttc aacatctttt ggcgtatata aatttgaatc ataccaattt ctaataatgc
    26701 cttcaatgta tttaactggc tttgatgtac cagttttatc tttgacgtat tcatatgcgc
    26761 aaagtatcat atcggggctc atattgtatt tattcattat atccataata ctcatctttt
    26821 cacttgggtc gagatatcgc ccaactattt tatttataga attaaacatt tttctaatac
    26881 ttggattttc agaagtagat acaactttat ctgtattaga ttttatagat gaattattgc
    26941 ttaatatatt ctcaatatag aaatttttta aatctaaaaa ttctattgaa taattaaaat
    27001 tatcatattc ttcattgtca tgtattttta taatcttctt ttcttcccag aatttccaag
    27061 cagataacac atcagacaat ggtatattta ggtttttggc tattgaatta ttgtcgaact
    27121 taggattaga agtaatatca catgcttgtc tatatcctaa aagataaact tttacgtata
    27181 acccgtccgc cattggcata aatatatcta taaagatatt gggaatagtg atttcaccta
    27241 aatctatttc attgctttct ttaaaaaaca ttttatcacc tcagattaaa ttatatcatt
    27301 ttttatatta tatttgtctg taaacaaata aaaggtcaca agattagcat gtaaatattt
    27361 tctaaaagta ttcattttga aaaggaggag atattttggt tataaaattc aaccaaaaag
    27421 taagaagaac attatcagta gcgattctat ttatggtatt aataataggt tgctttatag
    27481 aaaaggatga cagtttagaa acatacaaag aaaaaactaa ttcaaaaata aatcagtata
    27541 atatggatgt tatatttgat gatgagacta agaggttaat gtgcaatcag aatgttgact
    27601 acataaataa tacaaaatca aacatagata aaatatattt ccatatatat ccgaatgctt
    27661 tttccaagaa agattttgct ccttttgaaa aaagtgaaat gacaagggct tatcctaatg
    27721 gatttaacga aggatatata gatataaaga atatattaaa taataatagt aaaatggagt
    27781 ataaaattaa aggagacaaa aatgacatat tagaaataga attagggaaa gagttaaaac
    27841 caaatgaaag aatgtcatta gatataaaat ataacgtaaa aataccaaat tcaattggaa
    27901 gatttggata tggagaaaat actataaatg ttactaattg gtttcctata gcttgtgtaa
    27961 atgatgaaag gggatggaat ttaaagagtt atgaaactat tggcgaccca ttttatagtg
    28021 agactagcga ttttcatgtg aaactattga ttccaaataa atataaaatt gctcatacag
    28081 gaaaacttat tgatgataaa catgataata agaaaatgct atatgaaata gaagctgaaa
    28141 acgttagaga ttttgcattt atactaagta gtaaatttga tgtaaacaaa gtagattcaa
    28201 agggagtagc tatcaataca tataatttaa ataaaaagct ttctaaaaaa gcaactgaag
    28261 tggcaaaaga ttcaataaat atatttagtg aattatttgg aaagtatcct tacaaagaat
    28321 tttctgttgt agcaagtgac ttttttatag gggggatgga ataccctatg cttgttatga
    28381 tagaccaaag tttatataat gaaaaaaatg aatttttact agaatatgtt attgcccatg
    28441 agacagcaca tcaatggtgg tattctgctg ttggaaatga tgaaataagt gaaccctggt
    28501 tagatgaagc acttactgaa tattctacaa tagtttattt tgaacaaaag tatggtaaag
    28561 atatggcaaa caagcttata aaaactatgg agatacagac aaaaagttat ttgagtgaaa
    28621 atatatttaa gccagcaaat gagtataaaa attctactga atacagcttg aatgtttata
    28681 caaaaggcgc aatagcattt aatgaaataa gaaaagaagt tggagataaa gtattctttg
    28741 agactttaaa tgagtactat aataaatata agcataaaaa tgctaatgga agagcttttg
    28801 tggaactatg gaatagtaaa ggtgtagata taaataagat tataagtgaa tgtaagtaaa
    28861 tagtgaatgt aagtaaattt tgtgcagagt attaaatttt atttaatact ctgttttttt
    28921 ggtataatat aatttataag gcagaaaaag aggtgaagga atgctaaagt attgttcagt
    28981 agggagtggt agtagtggta attgccacta tatagggtat aaaaatacta atatactagt
    29041 agatgcagga ttaagtggca agagaataac tacaggtctt aaagacattg gtgtagatgc
    29101 agataaatta aaaggaatat ttataacaca tgagcatgtt gaccatataa aaggagcagg
    29161 tatattatca agaaagtttg atataccagt atttgctaat ataaaaacat ggtgttctat
    29221 gaaggacaaa ttaggtgaca tcaaagataa aaatatgaaa gtatttgaaa atgataaaac
    29281 ctactcatta ggtgatatca tagtaagacc tttttcaata gaacatgatg cgtctgaccc
    29341 agttggatat aatttttata cagagagtga tgaaaaaatg tctatagcta ctgatatagg
    29401 atgtataact caaaatataa aaaaacatct atataaatct aaattagtag tattggaatc
    29461 aaattatgac cctaatatgc ttatgatggg ttcatataca tatgctttaa agaaaagagt
    29521 aatgtcaagt actggtcatt tatccaatga agatgcagct aatttctgcg ttgaacttat
    29581 taatgaaggt acagaatcta tattattagc acatttaagc aaagaaaata attttcctga
    29641 gttagcgtat gagacttcaa aaggagtatt agcatcaaat gatatagtag ttggacaaga
    29701 tgtaaaacta gatgtactat cacgaaatga tgtttctaat gtttatgaga tgaagtagag
    29761 gtgaataact ttgctaaaga gaaattttga aaatgttgag gataataaaa ttttatactc
    29821 tataaagcag ggtatgattt tagcgatacc tgctattatg actggttcaa ctgctcttgt
    29881 aattttgaat cttccaataa aggcttatca agaatattta tcaggcttgt ttaatggaga
    29941 ggttacaaat attcttaact ttataaatga ttctacttta ggaattattt cattaataat
    30001 attattaaca ataagctata gttatggaaa aatatatggg agcaagtata cagtacttgt
    30061 tcctatagtt gcaatgtgct cttttttagt attttcacat ggtaatgagc ttaattctta
    30121 tatagaaata tttaaaacaa agtggttatt tacatctata attgtttcta tgacatcttc
    30181 tgtattgttt gtaaaactta cagaatcttt tgttacaagt gtaaagtttc atacagaagg
    30241 ggctgatgca gactttaata tggtagtttc ggctatagtt cctttcataa tagtagtatt
    30301 tttgttttct atttttagag tggtaatgat aagtctaatt ggcagttcaa actttcaaga
    30361 tatattttat aatttatttt caaatgtttt taataaaatg ggaacaaacc ttatgagtgc
    30421 tctgttgttt atttttttaa tgcactttat gtggtttttt gggattcatg gtagtaatgt
    30481 attagatacc gtcgcaaaaa atttatttga aaatagtatg gcaattaaca taaatttagt
    30541 taataataat caattaccaa cagaaatttt tactaagacc ttttttgata caatggtttt
    30601 attgggagga tgtggctctt tactatgttt agtaattgca atttttctta gtgaaaaacg
    30661 tataaatgta agaaagttag ctaaaattgc ttcaatacca gctcttttta atatcaatga
    30721 gatgctagtt ttcgggatac caattgtttt taactatatt atgtttgtac cttttgtaat
    30781 tactcctata atcttaaccg ttacaagtta tgtggctatg tctacaggta ttgtaccatg
    30841 tacagtttca gctgtagaat ggacctcacc tatattttta agtggatata tgtctacagg
    30901 ttcaataaga ggtagtttgt tgcaagtatt taatttatgt gttggtgtta tgatttatat
    30961 tccgtttata aaaatgtcgc aaaatagata tacatatatg tttaaaaata atatagaaaa
    31021 tttaacaaac ttattaaaaa ggtatgaatt aacaggtgaa cagcctaatc ttctaaacca
    31081 taatggtaaa ataggttcaa tttcaaaaat gttggcatca gacttgaagt ttgctatgaa
    31141 aagaggagaa atagagcttt tttatcaacc acaagtcaat tataatggaa atgttgtggg
    31201 agcagaggga ttacttagat ggaaacattc aataggaggg ttcatttatc caccactagt
    31261 tataattttg gctaaagaag aagggttctt agatgagctt ggagagtata ttattaataa
    31321 agcatgtatt gatttaaaga agagtgaaaa gctattgaga aatcctgtta agttctctgt
    31381 aaatatatct ccagaccaac ttgatgaccc taagttacca gagcaaataa aaaatatcat
    31441 tagtagtaat gatataaatc ctaatatgtt aggtatagaa ataacagagc aaattgcatt
    31501 atcaggttca caaataatta ttgaacgtat caatgcgata cataacttgg gaataaagtt
    31561 aattatggat gattttggga tggggcatag ctctcttata tatcttcaaa ataataactt
    31621 tgatatagtt aaattggatg gttcattagt taaagagata cttacaaata aaagaagtag
    31681 tgaaattata atgactattg taaatctttc aaaaaattta gattttgata tagttgttga
    31741 gtatgttgaa aatatagacc aaagggataa gttatatggt ttaggatgtg aaatatatca
    31801 aggatattat tatagcaaag caataccttt tgaagagttt gtagaatatg caaatcaaga
    31861 aagagagata taattttata agagcttgta aattctagta atgcatagat ttgtaataaa
    31921 attaagttta ggagaaatat atgaatataa gtatagtagt agtaggtaaa attaaagaaa
    31981 aatatttaaa attaggtatt gatgagttta agaaaaggct ttctaagtat tgtaagttag
    32041 aaattataga gttggatgat gaaaaagctc cagagaattt gagtgttaag gaaatggaaa
    32101 ttataaaaga caaagaagga aagaaaattt tagggaagat aaagcataat agttatgtta
    32161 tagccttggc tattgatggt aagggtttat cctctgaaga gcttgctaag actatgagtg
    32221 atttagcagt tagaggtaat agtagtctct gttttataat aggaggttct ttagggcttt
    32281 ctgatgaggt tttaggaagg gctgattata ggttatcctt ttctaagatg acttttcctc
    32341 atcagatgat gagattgata ttgttagaac agatttatag ggcttatagg ataaataatg
    32401 gagaaccgta tcataaataa atgatacggt ttttgttaat ttgacactta ataatattaa
    32461 aataacaaaa aagtattgaa agtatattgc atttaaggta gaattaaata aaatattata
    32521 acattataat gtttatatgg ttgttaataa aaatttggag gaaaatatat gataaaaata
    32581 atgttggcct gttcagcagg aatgtctaca agtttattag ttactaaaat ggaaagtgca
    32641 gctaaagaaa atggtataga gtcgcaaatt tgggcaatac cagaatcaac tatacaaaat
    32701 gaaatagaaa aatgtgatgt attattacta ggaccacaag ttagatatgt attacctaag
    32761 gctcaagaaa ttgctaagcc atataatata ccagtagaag ttataaatat gatgcactat
    32821 ggaacagtta atggagaagc tgttttaaat agagcgatag aacttaacaa cactaagtaa
    32881 tataaattat aatgtatttt taatatataa attgggagaa tcaaaggatg gatgaaaaga
    32941 ctatagaaat atcttttaat ataataggtt atgcaggtga aggtaaagga ttagcttttg
    33001 aagcaataaa agaggctaag aatggaaata tagaaaaagc aaaagaatta ttaaaagagt
    33061 ctagggaagt tataaataaa gcacatagat atcaaacaga attaatacaa aacgaagcta
    33121 gtggaaacag gactgaaata agtgtcatac ttatacatgc acaggaccac ttaatgaatg
    33181 gcatgaattt tcaacagtta gctgaggaaa tcgttgattt acatttgaaa ttacaagata
    33241 aataaaaatt aaagataata aattaagaga gttcttaaaa gatacattat gtgtagcaca
    33301 ctaattgtta gattattgat tcaatattta gtgagtaata cattaggatt attttgagga
    33361 ctctttttat atttagttta aagttaataa atatttatta ttaataatat aagattatat
    33421 gttataatat tataacatat aatttaagag gtgaatcatg ttaagaaatc aaccattata
    33481 tatacaagtt gtagatatat taaagcaaaa aatattaaat aacgaatata aaattgatga
    33541 aaatattcca acagaaaggg agttagagca agagtttgga gtcagtaaaa ttactattag
    33601 aaaagctatt gagatattag aatcagaagg atatgtagag aaaaaaagtg gaaaagggac
    33661 aaaagtaata agtaatagcc tttttaataa gctatcaaaa gcagagtctt tttcaagtat
    33721 acttttatct aaaggtcata agttatctaa agagactatt tcaattgaaa aaataataaa
    33781 tgatacaaat tcacaagtat ttagtatatt tggagaaaaa tgtagcaaga ttactagaat
    33841 gtattattta gatagtaagc catatatatt ttttactcat tatattcctt ttgatgaaaa
    33901 tctaactgtt gaaagtttta ataatgaaag ttctttatat atgtacttat ataggagaaa
    33961 tataaatata actagatttg aagatgaatt ttttatagaa gaatcagaac tagaggtatc
    34021 aaaggcttta aatctagcta aagacatatt attaggaaga aaaagaaaga cctatgatga
    34081 gaatgataat atagttgagc tatcatttgc aagatataat acagaagtac aaaactatgt
    34141 aattaaatac gaaatataat aagaatcctg agtttattga aatgataata tgctcaggat
    34201 ttttgtttag ttgtaaaaat aaaaaatatt ataacattat aatgtttaca accaaacatt
    34261 ataatgttat aatattttta ataaacaagt gatattatca attacataaa aattagttta
    34321 tgttatgaaa tcgttattgc attataaata aaggataata tcaataatac agggggataa
    34381 ctatggaaaa attcgcaagt tttttagagc gcaagattat gcctgtagca gcgaagataa
    34441 gtaatcagag acatatgaga gctgtaagag caggtataat agcaacatta ccactaacaa
    34501 tagtggggtc atttttcaca atattattaa acatacctat tgatgcttat atggatttta
    34561 tagctccatt taaagcaata ttagatatac catttagata tactgtagga tttttatctc
    34621 tatatgctac ttttgggata gcatcatcac ttgctaaaag ctacgattta gatacaacag
    34681 gtgttggtat gcttgcagtt atggcatttt tagtttctac aatagttcca actcaagtag
    34741 ttgaaccagt aggtggagtt atagaagctg gtagatggat ggatatggca aaacttaatt
    34801 cgccatcatt atttggagct atcgtaacat cattaattac agttgaaata tatcgtttta
    34861 tgaaggaaaa gaatattaca attaagatgc cagcaggagt tccagtagag gtttcaaatt
    34921 catttactgc attattaccg acagcagtaa ttttaatgtt attctgggta ataagacata
    34981 ttctaggatt tgatataagt gttgcactaa gcgctatgtt atcaccttta aaaggattct
    35041 tatcaggaaa tagtttaggt ggtgggttac tgacagtatt cctaataact ttattctggg
    35101 tacttggaat acatggtcca gctataatgg gaccagtaat aagacctata tgggacatgt
    35161 ctatagcaga aaatataact gcattcacag aaggagtatc agctcatgca atgccaaaca
    35221 tatttacaga acaattttta cagtggtatg tatggatagg gggagcaggg gctactcttg
    35281 cattagttgt aatgtttatg ttttctaagt cacaatatct aaaaagttta ggtagattag
    35341 gatttttacc agggttattc aacataaatg aacctataat atttggagca ccaatagtta
    35401 tgaatccaat actagggata ccatttataa ttggacctat aataatgaca attctatcat
    35461 atgttcttac tattacaggg gttataccta tgatggtagc aagattacca tttgcaatgc
    35521 cagcaccaat agcagcagta atgagtacta actggagtat actagcaggt atcttagtat
    35581 taatcaactt tgtgatatca tttgctgttt attatccatt cttcaaagtt tttgaaaaac
    35641 aacaattaca aagagaacaa gaagaaatga gtgaaaattt ataaaaatac atagatatag
    35701 aggttttgta ctatataaaa tatagaaaaa gcttataagt tattaagggt gaaggtagga
    35761 ggaatgacct ttgcctttaa ttttatatat tttaaataat gtaatttgag gaggagaaag
    35821 atggaaagaa gattaggaat atcagtatat ccagagcata gtaacatgga agatgataag
    35881 gcatatataa aaatggcttc aaaatacgga tttaaaagaa tatttatgtg catgctttca
    35941 attacaagac ctaaggaaga agttaaaaaa cattttaaag agattataac ctatgcaaga
    36001 gaattaggat ttgaagtaat ccttgatata gctccaaaca tatttgatat attacaaata
    36061 tcttatgatg atttaacatt ttttagtgag ttaaatgcta gtggaataag gcttgactat
    36121 ggatatgatg gaagtaaaga agctatgatt tctttcaatc catatgattt aaaagtggaa
    36181 ctaaatatga gtaatgatgt agcatacttg gataatataa ttacttacaa gccaaatgta
    36241 aataatatat atggttgtca caatttttat cctcaaaggg gtacaggctt gccatatgat
    36301 ttttttgtaa gatgttcaaa tagatttaaa aagtatggaa taagaactgc tgcttttgtt
    36361 aattcaaaat acgcaacaat agggccttgg aatataaatg atgggctgtg tacgcttgaa
    36421 atgcatagaa acttagatat tgctacagca accaagcact tattcgcaac aggattgatt
    36481 gatgatgtaa ttgtagggaa tgcatatgca agtgaagatg aattaaaaag aatgtctgaa
    36541 gtaaataaat atcaagttgt atttaatgta gtaactgaag aaaaaacttc tgaagtagaa
    36601 aagacaataa tggcaaatga gcaacacttt agaagagggg atataaccaa ccaagtagca
    36661 aggtctacag aagtaagaaa aaaatatgct aaagaaaatt tccctaagca tgataatacg
    36721 accatcttta aaagaggaga tgtagtgatt ggtaatgatg actttggaaa gtataaaggg
    36781 gaattacagt tgatacttca agattgtgca gatgaaagaa aaaataaggt gggtagaata
    36841 aaggaagacg aaataatact tttagacttt attgaacctt ggagtaaatt taaacttatt
    36901 ttagagggag agtaaagtga agatagacat attaataaaa tgtggaaaaa cagtagataa
    36961 aagtataatt gatatagcta tattagacga taaaataata gaagtaaaaa atcagataga
    37021 tgattctaag tatcaggcaa atcaaattat aaacctagat ggagaaaaat ttattagtgc
    37081 tggttggata gatatacata cgcactgcta cgaaagacta gacctttata aggattatcc
    37141 agatgaggtt ggaataaaaa gcggtgttac tactgtagta gatgcaggaa caacaggagc
    37201 tttagatata ggtaaatttt atgaagatac taaaaaatat aaaacaaatg tatatgcttt
    37261 aataaatatt gctaagcagg gaataacatc tcaagatgaa ctttcaagta tgatgaatat
    37321 tgatgaatat gaacttagaa gagcagttaa aaaatacaaa gattttgttg ttggaatcaa
    37381 agctagaatg agtaaaagtg ttgtaatttc aaatgatgtt gaacctttaa aagtagctaa
    37441 aagaataaaa aatgaactta atctacctat gatggttcac tttgggagtt ctcctccaac
    37501 gatagaggat atatttgact atatggaaaa aggagatata ttaacccata tatataatgg
    37561 aaagccaaat ggaatactta gaggcaatga ggttaaaaaa gaaatcatag aagctagaga
    37621 aagaggtata atccttgatg taggtcatgg aaccgaaagt tttagtatgg atattgcaat
    37681 gaaatctaag gatgcaggaa tttttccaga cactataagt acagatatat atattaaaaa
    37741 tagaataaat ggtccagtgt ataatctatc tacaacaatg gaaaagttta tatatatggg
    37801 ctattcactt gaagatataa tagataaagt tactaaaaat gcagcagatg caataagttt
    37861 aaaaaataaa ggtttaataa aagaaggata tgatgctgat ttaactatat ttgatgtggt
    37921 taatgaagaa aaagaacttc aagattcttt gaataagtca gtaatcacaa gtacgtctat
    37981 aaagccaaga gcagtagtag tcaatggaga atatttaaat ataggtaagt ctataggaga
    38041 gaatgagtag aagggagaaa ctattgtatg agtagtatat ttgaaaaata ctctgtaaga
    38101 cgtgttataa atgcttcagg caaaatgact atactaggag tatcaacagt agataaggaa
    38161 gttattgaag caataggtga agggtgtaaa aatttcttta taatagaaga acttataaat
    38221 aaaacaggtg aatatatagc aaatttatta gggtgtgaaa gtgcactaat agtttctagt
    38281 gcatctgctg ggattgcaca gagtgtggga gcaatgatag caaaagatga tatgagtcta
    38341 gtttacaatg taaataatcc taagaaacaa gttaaaaggg aaataataat tccaaaggga
    38401 cataatgttg attatggagt tccagtagaa gtaatgataa gacttagagg aggagaagtt
    38461 gttgaggccg gttatgctaa tatgtgtaac aaggaacata taataagaga gataaatgaa
    38521 aatacagcag caattatgta tattaaatct catcattgtg ttcaaaagag tatgctaagt
    38581 gtattagatg cagtacaagt tgctaaagaa tataatttac ctttgatagt agatgcagca
    38641 gcagaagaag atttaaatgt atattatgaa ttgggagcag acctagtgat atacagtggt
    38701 gctaaggcta tagagggtcc tagctcaggg ttagtaatag gtaagaaaaa atacatagat
    38761 aatgtaaagc ttcaatcaaa gggtatagga agagctatga aaataggaaa agaaaatatt
    38821 gtaggtctaa catgtgcaat tgagagatat ataagtaatg ataaagtaac tttaaaagaa
    38881 atggaggata agctaaatcc atttatagac aagataaata ctataaaggg agtgagtgct
    38941 agtataacta gggattcagc aggtagagaa atacttcgtg gagaaattga ctttaatgaa
    39001 gatataataa ataagtcaac acaacaaatt ataaatgaac ttagaagtgg agagatagct
    39061 atatacacta gagactataa ggctaatgaa ggcaagattg agattgatat aagaagtgta
    39121 actggaagtg atttagatac tatttataat aggataaaaa atatagtaga aagttagagt
    39181 gtagagtaag tgacattata atgatttaat aaattaaatt ttaccaatgg aggggataaa
    39241 tatgaattgt ataccacaat attataaaaa tagagtttgt ttaaatgttc ttgcaggaag
    39301 cataaaaaat gctaaagaag tatatgatgc ttgtgacggg catgtattga taggaatact
    39361 atcaaagaat tatagcactg tagaagcagc tattgaagat atgaaaaaat actcaaagga
    39421 aatagataat gcaatatctg tggggcttgg agctggagac ccaaatcagt caaatatggt
    39481 atctcagatt tctaaagaac ttcagccaca acatataaat caagtgttta caggtgtggc
    39541 tacgtctaga gcattgcttg gtcaaaatga tagtataata aatggattag tttctccaac
    39601 tggtaaacca ggatttgtaa aaatatccac aggtccatta agttcaaaag aaaaagatgg
    39661 tatagttcct atagaaacag caatagctat gatgaaagat atgggaggaa gctcaattaa
    39721 gttttttcca atgggagggc ttaaaacaaa ggatgaatat atagaagttg caaaagcttg
    39781 tgcaaagcat aatttttatt tagaaccaac agggggtata gacttagata acttcaaaga
    39841 gatagttcaa attgcacttg atgctggtgt agaaaaagtt atacctcatg tttatacatc
    39901 aataattgat aaagaaacag gtgaaacgaa agtggaagat ataggagtac tttataaaat
    39961 aatgaaagaa ttattgggat agatttatga atatattagc ttttggtgaa ataatgatga
    40021 gactttcagt acctgactac aagttcttaa cacaaaccaa tgaactaaat tatataacta
    40081 caggcacggg attaaatata ttatctggac ttaaaaactt tggatacaat acctatatgt
    40141 tgacaaagtt gcctaataat aatgtaggta aagcatcaag tgcaaatata agaaagcttg
    40201 gagtaaaaga tgactttatc acgtatggag ggaatcatat aggagtgtat tttcttgaaa
    40261 atgggtatgg agaaagacct tctgaagtga cttatttgaa taggttaaat agttcatttt
    40321 gtgagagtaa attacaagat tatgatattg ataaatgttt agaagaaatg gatatagtcc
    40381 atatttgtgg tattgctatg caacttacag attcagttaa agagattgct ttagaactag
    40441 ctagaaaatc ttatgaaaag gggataaaag tattctttga ttttaatttt agacaatcat
    40501 taaatccaga aaggacttat gatgatttag taaatgatta taagaaaata ctaccatatt
    40561 gtcatgggct gtttgctagt tatagagata taaataagat acttaatata gatagtctaa
    40621 atataaaatc tagttcagaa ttgattaaaa aagagtatga tatagatatt gtagctggaa
    40681 ctatgagaag atttgatgat atgaataata gatttataaa gggatatata tcaaatgatg
    40741 atggttattt tgaaagtagg gagtataagc tagaaatata tgacagggtt ggtgccggag
    40801 atggatatgt agcaggaatt atatattcat atttggaaaa tatgaagagt gaagatatag
    40861 ttgagtttgg ggttgctagt tcggtgttag ctcatacaac ttatggggat aattctttag
    40921 taagcacagg tcatgtactt agactgatga ataatgaaaa aatagatata ttgagataat
    40981 acatttgtat ataataaaat ttttatcttt tttagacaca tttttgactt gcttatattt
    41041 gttaaacaga gttattttta atgattataa atattaaatt aaaagttaaa taataaaata
    41101 gtagaaaata gcattaacta tagaaaaaat ggttaatgct atttttatcg ttaatattga
    41161 ttaattttat attatagaaa tgaacttttc taatgctgga tttgtatttt ttttattcca
    41221 tacaactaca acttcaattc tattttctac ttcttttata ggtactattg caatatcacg
    41281 ttctatcatt gtatctgtaa cacaaaatga aggtaaaatg gatattccca tgttagaaga
    41341 taccaatgat tcaatagtat taagattatt tgaacgttgt accacattag gtacaaaccc
    41401 tgcttcacga tatctattct gtatcattga cttttgtcca tactcatccc ctgtttcctt
    41461 tacaaaaata aatttatcat gttgtaattc aattaaatcg atagaatcct cattgtaaag
    41521 tggatgacca ggaggtaaaa gagctaccaa agaatatctt tctacagttt tatattcaaa
    41581 atcttttaat ggttgatttt ctggattaat aacaaaagcg aggtccatag aattattttt
    41641 tactaagttt aaaagttcgg ttatttcatt agtacaaata tccatagata tattagggta
    41701 tgtattagaa aattctttta aatattgttg aagtttgttt ttttcatatc ctattaaggt
    41761 tccaatgctc aaagttccaa aaaaaccatg tgcaaattgt tgtgtttttg caatagcatc
    41821 attgatattt tttattatag tacgtgcctc agataaaaaa acttttccag ctggtgttag
    41881 ttcaacatga cgtttacttc ttgtaaatag agttacattt atttgttctt ctaaagcttt
    41941 tatttgctgt gtaacagcag tttgagaaat ataaaatttt tctgctgttt tggtaaaact
    42001 tagattttct gctacagata taaaatattc taattgttta gtattcaaat aatcacccct
    42061 atttaaactt gattgtttgt aaaccttatt tatctataat taaagcttat tatagtataa
    42121 gaaaatttac ttttaaagaa tattagaaaa tatttgtata aaaatatatg ttttaagtat
    42181 atctttacat tagattttat aaatttatta ataagaataa cttatatatt ccaatgaaaa
    42241 cgatattgga tttaagtaag tttgtctcat aaaatgaaag tatatcaatt gataatactt
    42301 taaataagaa gggagaaaaa atggaagata aattttatgc aaaaggcaac ggaaataacg
    42361 gatatattaa aaatcttgaa gtttgttcct ttaataactt agatggaact tgtggaatgt
    42421 ttcaaatggc tctgtacaaa agagatgaaa aatactattt atatggatgc tgttttggag
    42481 gaaataaaaa aaatggagta atgattagcg atattacaga cccttataat ccacaattta
    42541 taaaacattt tcaaatgtta gaccctaaag agtatcctac aacaacaact cccaaaattc
    42601 aaatagcaga tgatttaatg atagtagcaa tgagttgtgg aagtggacca ggagcacttg
    42661 ttgaccaagc taaattagca aatattaagt gtgaagcagg aattagaata tatagtttaa
    42721 aagaagaccc tttaaatcct aagtttttag gatattggga ttgtggctta aagcatgtaa
    42781 tgggtgttca tagattcatg tacaatggtg gaagatatgt acatttatca agtgattgtg
    42841 ttggctttga aggtctgatt tatagggtca tagatataat aaatcctact aatccagtgg
    42901 aaataggtaa atggtggaga ccagaccaat atgcaaatgg atatccaaat agaacttttg
    42961 atgcaggagc acctcattgc ccagaattta tggataaagg atggcttcat ggacctccat
    43021 ttgtaagaga cggaaaagca tattgtggtt atggaggagc tggtttagtt gtattagatg
    43081 ttgaagattt aacaagacca agatgcttag gtgaattgcc atttatgcct gcattttcta
    43141 gtagacttgc aggtgcaaga actcatacag cattaccatt gccaggaaga gatttagtcg
    43201 ttgttcaaaa tgagggagaa agattccagt tctttaaacc agataacatt acagatgttc
    43261 aagctatgaa taatatacat atggttgatg ttagtgaccc aacaaaacca acattaattg
    43321 ctcaatttcc atatcctgaa gttccaaaag atttccctta tcctaacttt aatgttgcgg
    43381 gattaggaaa accagggcca tttggcccac ataatcttca tgaaccaatg gataataagc
    43441 catggttaga gcaaagagga gatagagtat attgctgtta tttccatgca gggctaaggg
    43501 tttatgatgt atcagaccca tattatatca aagagctagc atattttata ccaccaaatc
    43561 caaataaaac accagaagaa tcttatttcc caggattccc aggaccacgc ttggcagtaa
    43621 cagaagatct tatcgttgat gatagaggct acatcatcat agatgcttta gatgatggat
    43681 tctatatatt aaaaatgaaa gaagattaaa taaatactaa agagggagag ttgaaaatga
    43741 aaatactagg tatttctttt ggaacaaaaa atggaaataa tgacacaatg tgtaaagttg
    43801 cacttaaagg tgccaaagaa gcaggggctg aagtagaatt tattcaaatg tcatctatta
    43861 acattaaaca ttgtactgga tgttgtgcgt gtgttaaaac tttattatct gggaaaggta
    43921 gtatgtgtgt attaaaagat gattttgaat ggttgcttga caaaatgaaa gatgcagatg
    43981 gtatagtagt ttcagaccct atttttgaag aaggggcatc aggattattc catactataa
    44041 tggaccgttt tggacccaga gcagatagag gaaataacat tataggaaca aaagttgcag
    44101 aagctatagg aggaaaaatt ccagattcaa gaatgcttaa tgataaagta atatcattta
    44161 tgggaatagg aggttctgac tggggtacaa gagttcaatg tgaacatgct atgctagctc
    44221 tcataccaat gtggaaagtt atagataatg cttggttccc atgggcaaag gaattagtaa
    44281 tggatgatac aaggcttgtt caagttcatc aaattggttt aaatatagtt gaagcagcaa
    44341 aagattttga aaaagcttca tatcaaggag aagaaggtgt atgtccacat tgccacaata
    44401 gattattcta ccttgagcca ggtactaaaa aggcaatttg tgctctatgt ggtatagttg
    44461 gagagttaga tactataagt ggaaaaacta tatttagttt tccagaagag caattaggtc
    44521 atgctcatga tactttacca ggtaagttta tacatggtga tgatattaag aaaatggaag
    44581 gtcattatgc agaagttcgt aaaacacaag aatttaaaga aagaaaaaca tcttataatt
    44641 ttatagagcc attaactaaa gaaaagcaag ctggagtttc attaggataa taattaaaat
    44701 actaagactc ttttttaagg tatgttagat gttataggag gcttattgta tgaatgaaaa
    44761 gtcaagtttt aaacaaattg aaattatttt agcagttatt tttttggtac ttacatatta
    44821 caaggttaga ttaactccag catttattgt tatatttata ccactatatt taagttattt
    44881 tgcagtatct atgattgtaa atcaaatagc aattaagcta ttggagataa ggcaagctag
    44941 ggaagctact aattacaata taggaaatgg atagaaagaa aaaagaaata ttaacactgt
    45001 ctatggggat tgctttacta cctcctttat gggcagtatt agcaccttat ataggaataa
    45061 aaactggagc tgtagcacta atctgtgcag gattatatgt aactaatggt aataaacaaa
    45121 aagatggatt aaaaataatg tttggttttt ggtgtggaga tttatgggca gtgttagcca
    45181 ttttaattat gggatatatg aatttcaatc aaaacctaga attattttta acacttagta
    45241 tattaggttt ttttgcagtt gtaattgcat ccttatttga aaaaataatt ttcctaccat
    45301 catggctttg tggttgggct ataggtctaa ctattatgac aggtgaaaat attattaatt
    45361 tacaagatat ttgtattcaa attgctgtag ctatggcagt aggagtatgg tacgtgggtg
    45421 caggtgtaga tttgtttaca atatatattt tgagtaaaga taggaaaaag ggaaattgaa
    45481 agcatgtgaa tatactttga ttataggaga atggctatgg gttttgaatt taaaataatg
    45541 agaagtttaa tatatgtagg acttgccaag gaagaatata gacctaagct aatggactgg
    45601 ttatatcgtc accatattcc agatagtatt agcacttttg gaccatattg tactaaatat
    45661 gccttttatc aagcatatcc tacaccaaat gaaggtgagc gttttggtgc acgtaagatg
    45721 caactaacag aacattattg gcttgtagat gaacatatgc ctgagatggc aaatagaatt
    45781 atgacagaat atatgcctat ggatgttcta cgttggcaag ggtgtatacc agatgtagaa
    45841 aataaaaggg ttcatgaaaa tgcagaaagt ggagatgcag gacgtgcagt aggtggagat
    45901 aatggatgtc caccatttat atttgccttt gttccaataa actgggaaga agactttaga
    45961 ggaaaaggac gtactgtaca agatggacca aactatcgtt ggcaatttat gattaagtat
    46021 ccagatggta tctctaaaga agaaggagaa aaatggttct atgatgaggt agtgccatac
    46081 tttacaaact gttgctatgt taatcgtttt gtcagtagta aaataatgat taattatgga
    46141 gcaactgctt ttgaccgtgt atcagaacta tggtttgaag gggaagaaga atggtataaa
    46201 gctgtggttg aagagacaaa gtcgtttatt aaaaaaccag aatgggcaca agaagaggag
    46261 ttcccatatt taaaaccaca attcaatatc gcatcagtat tcttaggtga tatagcaact
    46321 atggatgcat actcacagta tcgtggatat ataccaatga gataaaaatt atagtttgtg
    46381 ataagtagag gaggcattta ctcttactgg tagaagaaga cttattgtat ccttaaaagt
    46441 aggtgaatat atagttttat atttaaattt atataaaact aagactaata aatatgaaac
    46501 aatagaatta gaataatttg ataatatttg ttaaaagagc atttagaatg tgtttaaaga
    46561 ttaagatatt ccttttatgg tagcagatag ttgaaataat aaaactgtta tcatgaaagg
    46621 aatattttta tgtataggaa atttttaaaa ataaaagtta aatatgttta agaacatctt
    46681 aaagtgaaag aatcattgtt agaaatatgt agacaatata gtctttataa cgtatcatat
    46741 taacaagttt acgcttggat tatgaaataa aaagagtaat tccaaaggtt gtaaatacta
    46801 tgctgacttt gatacttcaa agtttaggtg attttgtaat tgttaataga aatacgttta
    46861 atgagcataa agaatttatc taataatagg agaatataat gtatacaatt ggacaagtat
    46921 ctaaattttt aggaatatct agagatacac taaaatttta tgaggacaaa ggattagtaa
    46981 atcctaagaa aaatgatgaa aatggatata gaatatataa tcaggttgat atctatgata
    47041 ttgcaacaat aaacttttat agagaaattg atatagaaat taaaaagatt caagaaataa
    47101 gaaaaagtaa gagtataaac aatttagaac tcttactaga agagaaggaa caaatcatac
    47161 taaaagagat agaatataaa aagcttctct taaaaaaggt tcagttagtc aaagaagatt
    47221 gtgacaaaat aaaaacatat tttggaaaat acacaataaa agaaatgaag cctttggaag
    47281 taaaaggtaa aataaaacat gttactaact atgaggaata tgaagcctta aaagagaata
    47341 caaacaactt aaaaaaagca gttacattaa ctgatttaag aagagtaata aattttaatg
    47401 aagaaggtat aatagaagaa aaatttataa ttgtaaggga agtagatgac tacaacaaaa
    47461 tcatagaagg tgaagttcta tctcatccca attgtattta tactattatt gaagatggca
    47521 gatggtcaac tggaggagaa aatattgata ataaagtgga agacagatta agagaaatag
    47581 caatagaaaa tgaatgtgaa ttacttggaa tagtctatgt taatatattg cttactactt
    47641 atgaagaagg gattgagcgt atatttttag agatttatgc acctataaaa taatataaaa
    47701 gcattgacct gggacttact cataggttta aactcatgat ataagcagtt ataacttata
    47761 tagcaattaa atattaattt gaaatgagga ttacttatga gaacagagaa atcattaaaa
    47821 aggcctatag ccagttttat tattctaaca aatataattt ttttaccact ttttttattg
    47881 gtagtagtga ctataatgtt aaaacttcca acagtgatat ctgacattgc gttgtgtata
    47941 tcagcgtggt catccacttt tgcatttatg atattattta aaaaaattta tccaggtaag
    48001 aaatttttag tacacgtaaa agatagattt agaaataaac ttaaattttc aacagtatct
    48061 ataataatta gtatacaagt cctaatagct gtagtagtta tatttatatt agcatctaaa
    48121 aatcatggaa taatgcctaa ctttacagtt tcatcatggg gagcatttat atatttattt
    48181 ttaaaaaatt tatttgcagg atcattaggt gaggaattag gttggagagg atttgttcaa
    48241 aatcatcttc agaaaagaca ttctccttta aaagcatcca taatagtagg tttttggtgg
    48301 gggatgtggc atttaccaat atggtttaca acaggattca aaggacttga tttaataaaa
    48361 tatattatat tttttatgat tgcaattata tcaatcagta ttataatgac aactttttat
    48421 aatctaaata aaactttgat aatacctatt gtaatacatc aactatttaa ttttttaata
    48481 gggataatta atggagattt aatagagctt ataaattact atgcaatgtt atatttaata
    48541 tttgcaattg cattaatagt tataaatcca ggaaatgtat tatataaaaa tattagagag
    48601 taatatatat ctttatggta agatataaag atattattag aagaacatcc aaggaggaat
    48661 aaacatggtt ttactgattg ttgatgcaca aaagttaata acaaacgaga ggttatataa
    48721 atttaatgaa tttgtagtaa atgtagaaaa tttaattgat acagctagaa aaaataatat
    48781 agaagtaata tatgtacgtc atgatgatgg agttgaaaat gaattgacta aaggtaaaaa
    48841 tggctttgaa atatacgaaa aatttaaacc atgtaatgga gaaaaaatat ttgataaaaa
    48901 agtaaatagt gcttttaaag aaactggtct attagaatac ctaacaaata atggtgaaaa
    48961 agatattatt attgctggtc tccaaacaga ttattgtatt gatgccacta taaaatgtgg
    49021 atttgaacat ggatttaata taatagttcc agcttattca aatacaactg ttgacaattt
    49081 ttttatgtca gcagaacaat catataaata ctacaatgaa tttatatgga atgaaagata
    49141 tgcgaagtgt atttcattag aggaaacact tagaaaaatg aaataaaaat agagtatgaa
    49201 ttgtatatgt acataagttg atttcataaa aaaggatgtt aaattccaag ttaaaaatta
    49261 gattaaatat attatattat agataaggca catcaatttt attttaaatt aatgtgcttt
    49321 ttaattgtag taatttattt ataatcaata tgatttttat tatttaaatc aatttttctt
    49381 gagtttcttt gtctaaagaa acttttttta tttataaaat ctacagttat attatagtat
    49441 ctattttaga gaagtttaat ttttgtatca atctaaaaca aaagttatac ttaaatgaaa
    49501 ttgaaaacga taaaattctc aaataaaata agtattgtgg aggtgatgaa agaatccaat
    49561 gataatatga agactaatct taataagaaa gtaggggtta atggtagtgg acaaagaaat
    49621 tgtatcaatt ctccagattt tattaaatag cacattgatt acaactaatg gattacaaga
    49681 ggagtctaat tcatcaaaga gacaaattac ttatagaata aataaaatca atgacatgct
    49741 taaagtaaaa aatgtaccac ttatatgttt aagagctgat aaagatatta tcgttagaaa
    49801 agaaacaaaa aaagcaatta aagaaatttt agaaaaaaac tattctaaga atacttatta
    49861 ttttagtaag acagaaagac ttttatatat gtatttaatg ctttttatta acatggatga
    49921 tatttcaatt aatcatttta taaattctat aaaagtaagt aggtctactg taaatcttga
    49981 tttcaaggat ttgataccag agcttgaaaa gaagaacatt aaagttaaga acaatcgtat
    50041 aaatggatat tacatagttg gcaatgagat ggaaattagg agagtgctta ttaaaaatat
    50101 tatagaaact ttgtctaatg agaaaagttc aagagtattt gatattttta ttaaagaata
    50161 taatttagat agttttgaag aggctaaaaa aattatatta aagctaataa aaaaatatga
    50221 aattactttt gttgaagata gattagtaga atttatatat atatttatct ttctaaaggc
    50281 aaggatgtat tcaactagaa tagttactca ggaaaatgta gatattccta atatttcagt
    50341 tatgagttca atgaaggagt ataaatttgc taaggaatta ttagaagtat atgggagtga
    50401 agataagata aagcctcaca atataatgta tattagtgct tggattttag gtatatcagt
    50461 aggaaattat gaagaagata cagaagataa ggatgtaatt tcaaaaattg taaataaaat
    50521 gatgacaaag tttggatatt taagcggagt ttactatata agccaagaaa aaatatttaa
    50581 acaattatat tctcatttta gacctgccta ctatagactt ttatttaaat tacctattta
    50641 taatccgatt tgtgaaaaag taaaagaaga atataaatta gtttatagaa ttgtaagtaa
    50701 tgcaatgaaa gagttttgcg gattatttgg agaagaaatt caggaagaag agttagcata
    50761 tcttacaatg cactttgcaa cacttttttc aaataaaaaa gaatttgatg gttttagaaa
    50821 aagaatagca ttaatagttt gttcaaatgg cgttggtagt tcagctattt tacatgcaga
    50881 acttacaaac ttatttcctg acttacactt tataccaatg tcggaatcag ttggattaga
    50941 aaatataagt gaacctgtag atattgtatt tactactaat tataacgcag agggtttaaa
    51001 aacagatgta ccagtaatta aagtaagccc tgttatgacc acaaaagaaa aatataagat
    51061 tacacgtgaa gtgtatattc aattaggtga tattttttta agacaaccta aaatagatga
    51121 ggttatggat ataataaaaa aatatgcaaa tgtaacctct gaaagtattc tttcaagtga
    51181 gctattagct tattttacac agatagagaa ttttacatct aaggaaggag aggggcctat
    51241 gctaagtgag attactaatg aaacactagt aaaaataaag gtaaaagcta agaattggga
    51301 ggaagctatt agacagtcag cttctgtatt agttgaaaat aacaaagtaa ctgaagggta
    51361 tgtagatgct atgattaact cagcaaaagc atctggacca tacatagtaa ttacaaaaca
    51421 tgttgcactt ccacatgcta gaccagaagc tgggtcaaaa gagattgcaa taggcattgc
    51481 tactttagat agtcctattg agtttgggaa taacgaaaac gaccctgtaa aatatgtatt
    51541 ttgtctaagt gcaatagaca ataatagcca tttacgtgct atgtctgagc tagttgaact
    51601 attggaagaa gatgagtttt ttaaggtttt agatagtgct aaagaagcta aagaaattat
    51661 tgattttata aaaacacacg aattataaag gaggatttaa ttatgtataa aattttaatc
    51721 gcatgtagag caggagttgg ctcaagttta atgttaaaaa taaagactca acaaattatt
    51781 aaggaaaata actttccaat tgaagtagaa catggttcat tggattcact aaatggattc
    51841 aatggagatg ctgtagaaac attaattgat gttgctgaag aattaaaaaa taaaaatttg
    51901 aagtttgata taattgggat tcacaatatt gttgaccgta atgaaataaa gacagcacta
    51961 gaaaaattcc ttgcttcaaa agagggataa atttaagatg ataaggagga atatttatgg
    52021 agtttattat tagtttgctg agtacacctg ctgttttgct tggcgtagtt gcatgtatag
    52081 gattgattct tcaaaagaaa tcagctgttg aagtatttac aggctcttca aaaacactta
    52141 tcggtttttt gatatttggt attggtgcct ctgctatgac aggagcactt caaaatttca
    52201 ataaactgtt ccaacatggc tttggaatta ctggtgttat agcttcacca gaagcagcta
    52261 cagcacttgc acaaggtaca tatggttttg cagtttcatg tacattaatt cttggattca
    52321 tattaaattt agtatttgca cgtattacaa agtttaagaa tattttcttt acaacaggtc
    52381 atagtttgtt cttttcttgt gtattagttt taattatgaa agcacatgga tttgataata
    52441 caatcactat tttaataggt ggaactatct tagggtttat gtctgctgca ctacctcaat
    52501 tctgtcaacc atttatgcgt gaattaacag gtggcgacga acaagctatt ggtcacttta
    52561 acatgattgg ttatggttta tcaggttata ttgggcgttt attttcaaaa cataaagatg
    52621 atacaacaga gactatagaa tttcctaagt ggttatcaat attcagagac ttcttaatgg
    52681 gtctatccat agttatgtta atcttatttt atattgcaac attaaaagct ggtcaagcat
    52741 ttactcaaga aattgctggt tcaacacatt ggttggtttt tccgcttata gaggcattta
    52801 catttgtggc aggtatgtca atattgatgt caggagttcg tatgttctta gctgaaataa
    52861 ctgcagcatt tgtaatcatt tcagaaaagt atattccagg ttcacgtcct gcgctagatg
    52921 ttccaaccgt atttccatat gcaccaaatg cagttattat tgggtttata tcagcatatg
    52981 ctgctggtct attagcaatt gctattatgg catcatttcc tagtatattt cctgtagtaa
    53041 ttattccagc tgctcacata tgtttcttct caggaggtac agctgcaata tttggcaata
    53101 cttcaggagg atggagaggg gctattgctg ggtcatttgt tgtggggtta ttacttgcat
    53161 ttttaccagt tatactatat ccagtttatg ggactcttgg tatagaagga gcaactttcc
    53221 ctaatattga ttacaacgta gttggttcga tattacataa tattttacaa tttataaaac
    53281 ctatttagac taaattatat aaaagtatag tcatagttac tatgatttca aggaggatac
    53341 atcttatgga aaatacatta tctgaatttt tagataatat atctaatgaa ttgtcagaat
    53401 ttattgcctc aatagatgag acatctataa ataaagcatg cgaattaatt cttgaagctg
    53461 aaaaaaatca cggacgtgta catgtgactg gtattggcaa accaggacat gtatcgggat
    53521 atatttcatc attgctttca tctactggaa cgtcagcata tatattgcat ggtacagaag
    53581 cagtacatgg gtcaagtggt caagtagttg aaggagatgt tgttattgca atatcaaata
    53641 gtggtgaaac tcaagagtta aaagcaactc ttaagactct aaaagtaaat ggagcaaaga
    53701 taattggtgt aagtggtaat gagagttcat ttttaaaaaa tatttctgat atattcctgt
    53761 ttgcaggtgt taagcaggaa ggagattgtc tcaataaagc tcctcgtgct tcaattttag
    53821 ctgaaacaat aatattacaa tcattaagtg ttgtattaca atatgctaaa ggtcttaata
    53881 cacaggagta tttgaagtgg catccagcag gaagtcttgg aaagtctatt agagagggaa
    53941 tataatttta tgaaatataa agggattata tgtgcaatga taacaccatt tgatgaaaat
    54001 caaaatatta attcacaagc aacatgtcaa ttaattgatt atttgattga aaagggaatt
    54061 tatggattat ttattttggg cactaatggt gaatgtcatg tattaacaga tgatgaaaaa
    54121 gttgaatttg caaagattgt tattaatcat acaaataatc gtgtacctgt ttttgttgga
    54181 acagggggta attcaactcg tgaagttgta gatttatcta agagaatgga agcgattgga
    54241 gcaagtgcat tatctattat tacaccatac tttgttacac caacacaaca ggaattaatc
    54301 ttacattaca aaactattgc taattcagtt aatttaccta ttataatgta taatatgcca
    54361 ggtaagactg gaattaatat tgaaccagag tcagtacgtg aattatcaaa gataaagaat
    54421 attgttggaa ttaaggatag tagtggtaaa cttgacaaca tgaaagctta tattgaagca
    54481 acgaagaatg agaattttag tgtgttttca ggctcagatt cacttattct ggatagtcta
    54541 aaagctggta gccaaggagc tgttgcagca acaacaaact tcctcacaga gattggtatc
    54601 tctatctatg aaaactttat gaaaggggat ttggaagaag ctcaaaaatc tcaaagtagt
    54661 atagaagaac ttcgacgtat actgaaactt ggaacaattc catctgttat gaagaaaact
    54721 attgtcttga atggaattaa tgttggaact gcacgacttc ctgtaactga accaactggg
    54781 gaagtacttg aagaaattaa acgagtagtt gaaaattata ggacaatact taataaaagt
    54841 agtgagaata gataatataa atagggaaat tacactggta tataattaat atatatatta
    54901 taaaacatga ctaaaattaa tgaataagta aagtggtttg atgagtatag aggtgataat
    54961 atgaaaaaga tgaatataac caaaagaatg tcagaatgtg gggctcttgc aattgtaaga
    55021 gaagaaaatc ttaaccgtgc atgtgaaatt gctgaaggat gtataaaagg tggtataaca
    55081 gttatagaaa tgagttatac cctaaataat gctggagaaa taattcaagg gcttaataaa
    55141 aagtatggtg aaatactttg tgtgggagca ggaacagttt tggatagtga aacagctcgt
    55201 catgctatat tacatggagc ccaatttatt attgcaccaa attataatga aggtgtagcg
    55261 aagatttgca atagatatca gattccttat gctccaggat gtacatcatt gactgaggca
    55321 gtagacgcac taagtttagg agcaactttt ataaaagctt tcccaatatc agatttctat
    55381 ggacctaaac tagtaaaggt atttaagaca ccaatacctg atatgccagt tttagcaagt
    55441 ggagggctta atattgaaaa cctacatata tggttagaaa atggagttga tgtatgtgga
    55501 tttggtggtt tattaactaa aggttctgtt gaagatattg ctaaaaatgc taacaagatt
    55561 cgtgaaatca ttaaaaatgt aagaaaaatt taacataggg ctgtatcata gtatcttata
    55621 attactatga tacagccttt ttaatattat tcaaatttaa aacagtttac atttctatta
    55681 tattacatat aatttcagta attttatctt aatttttcta tctggaaaaa aatgatttaa
    55741 aacttaagtt atgatataat ttcattaaaa gaaggcgatt tttagtaaat atgagaaaat
    55801 aatgtgtttt taggggaaaa gttaaataca gatttaagtg aacaagaatc gataattaag
    55861 atattaaatg gtgaataggg catcaaaaaa attactaaat taaaagtttt agagggagaa
    55921 tcttagcaag tgtgtgtgaa aattcaattt caaacaaaaa taattgtaaa tgaaatcaat
    55981 ttatacacgt tgaagattca cttttatcat tatattaaaa agcagagtga attaaaagtg
    56041 agtctaaaga taggaggata attaaaacaa tgaaagaaga cattaggtta catcgaatgt
    56101 gtaaaaaaga acaagcaaca aagaatgaag ttatatcaga ggatattcta aaatctatga
    56161 gtattggggt cagtaaacat tttttagatg attcatttac aataatatgg ggaaatacat
    56221 cattctatca attattagga tatacagaag aagaattttt agttaaattt tctagtttaa
    56281 aagattatta tgaacagaat ctttatcatt ttgaatctat gaaaaatcat tttttagagg
    56341 cttatcatca tggcgaaaag agtatagaat atcaaatttg catttcagca aataatggag
    56401 accctgtttg ggtaataatg actggtatat taattgaatc acaagataat gagaaatcaa
    56461 tggtctatat attgtattca aaaattaatg agttaaaaat aaagcaagaa gaactatctg
    56521 atatggaaaa agagagtaca gagaatttta aatggatgat gtcagagtat gctgggaatg
    56581 tttatattag cgatatggat acatatgaat tactatactt aaataagcac tcatgcaata
    56641 ctttacaggc atcagcaaat gaacttattg gaagaaaatg ttatgaggta attcaaggta
    56701 gaacttcgcc atgtccgttt tgtacaaatt cgtatttaaa aaaagatgac atatatgaat
    56761 gggaatttta taataaaaaa ctgaaacgaa catttataat taaagaccgt atgttgaatt
    56821 ggcaagggcg aagagttcgt attgaattat cttatgatat gtatagtgct gaatataaat
    56881 tagcaaaaaa agatcaggaa agagaatcaa ttttgaaaac tattccagca ggaatggtta
    56941 gattagatgc aagagattat cttactatac tttggtgtaa tgatatattt ttgaatatga
    57001 ttgaatatac aaaggaacag tttgcagagg aacttaataa tcaatgtgga tatttatttt
    57061 ctgaagatta taaacgtagt aagaaactgg cacaagattt gaaggagtct ggggataatg
    57121 ttgtatttga agcaaaaata tatacacgtt caagggaaga acgtatatgg actgttacat
    57181 tgtgttatat cagtggggaa gacagttggg atggaatacc atctttttat agtataggta
    57241 ttgacataac aaaggaaaga aaacagattg agaaattaca gcatatatca gagaaagatg
    57301 cattaacagg aatttataat cgtgctgaga ctgaaaggca gattaagaaa tattttgaaa
    57361 aaaatttaaa tgttatgggt gcactgttta tgattgatac agataatttt aaacagatta
    57421 atgatacaga agggcatatg attggagata tagtacttac tgagatggca tcaggtatga
    57481 aaaaaataat gcgtgacagt gatgttgttg gaagaatagg tggagatgag tttacaattt
    57541 ttatgaagaa tatttcctca gttaaagatg cagaaaagaa agcagaagaa ctattgtata
    57601 tgttccgtca tctatttcag aaagaaaaaa gttttctaaa agtaacttgt agcataggaa
    57661 tagctatata tccaaaggat ggtactacat tcaaggaaat atatgcaaga gctgataaag
    57721 ccctgtatca agcaaaaaat atgggaaaaa ataattatgt aatctacaac caagattatt
    57781 ttaaagaatt agaagaattt gattgttctt ctcttggtac agttattgat tcagaaaaac
    57841 aatacgctga atatcctgat aatcttacac gttatatatt ccgtatgctt tatcagactg
    57901 atgatataga ccaggcgatt aatatgatac ttgaggttgt tgggaaacag tttgatgtaa
    57961 gtcgtgttta tatttttgaa aatacagaag atggtagata tacttctaat acttatgaat
    58021 ggtgtaatga aggaatctct tctcaaatgg cttatttgca aaacagcaat tatcaagact
    58081 atgaggatta tgaaaagctt tttgaggatg aattagtttt ttattgtcga gatatccata
    58141 cattaagtcc taaactagaa gaattgtttt ctagtcaagg tatccactct acacttcaat
    58201 gtgcatataa agaagataga gttttcagtg gatttgttgg atttgatgaa tgcacaggac
    58261 tacgtctatg gtcacaagag gaaataagta cattatcatt gatttctcaa attatatcaa
    58321 tgtttttaca acgtaaaaaa aataataaac ttaatcaaca gattcaacaa taccagaata
    58381 ttttagataa tattgaccag tgtatttgtg tgattaataa agaaaataat tttttattat
    58441 atgtaaataa aaaatttaaa aatacatatt ctaaattcca aattggacaa ccttattatc
    58501 ttgattctat agatattcat aagatatcca ttatatggaa taaaaaagaa gcatacctat
    58561 gtactagcac gatttaatgg taaagtaaag tttatattgg acttaaatta aatttcgttt
    58621 taaataagat attattttag ttgcttactg aaaagactag aatctatatt aatgaattat
    58681 actaatttta taccactatt aaaatattgt ttgctaaaaa taaaaaatag ccttaaaaca
    58741 gttgattata aaaaattaac tgctttaagg ctatttttat ctttgtgacg aaatagacac
    58801 ttgccattta gaatgtgaca atatagtagt tgtttagaaa aggcacaaag cattatactt
    58861 taactaaagt aaaatgtatt ttgcttttag aataaaaaca attaggaggg agctataatt
    58921 gaaaaagata atatatgtat tatttacaat tgaactatta atagtatctt tattaggtct
    58981 aaatatagtt aaagataatg aaattaataa tattttatat aacgatacaa caagtatatc
    59041 tgtaatgttt aaagattata aaaagttaaa taaaaattat agtaagtgga ttaaagatat
    59101 tgcagatgaa aataatgtgg ctatatcaaa gtatgttttt aataataatg aaaaattatc
    59161 tatatatacg actgatacaa gtttgaataa caatataaag ttaaaatcag gaaaatttcc
    59221 taatactaat tcaaatgaat ttattagtaa tataaacact aataatagta atcaagtagg
    59281 taaattctca actatgagta aagacatatc aattttaatt agggattttg gtaaaataag
    59341 tgaagttgga gaatcaggaa tcttatatat ttcaactcaa aatgaagata caataaataa
    59401 aatattaaga gaactaaatg tagacagaag tatttttgta gcaagattac atgatagata
    59461 tgttaactca aatttatact taaatccttc aataattaga gatttaatac taattatcct
    59521 ttgtttcttg gctacaataa tacattattc aattagtgtg agtagagagg cttctatttt
    59581 aagattaaat ggatactcta agctagatat aattgctaga gttataaaaa atatacttag
    59641 aattatgatt ttatcatctg tcacagcatt attaatatat ataatctata ttttaaaatt
    59701 aaatataggt gttagagcat gcttatactt tgctatgttt tcgattatat gtattttgat
    59761 aaatattttg atatctatat taatagttgg ttttaatagt agaagttcta aatatgtgct
    59821 atctctaaat ggaaaaaaat cttatggttt tgtaaatata atgcatttca cattgaaaat
    59881 tgtatttgta tcatttctta tattatccat aaataactgt attttaaatt ataatatgct
    59941 acaaactcag ttaggaaatc tatctgagtg ggataaagca aaaaatgttt ataatcttac
    60001 tcttaaagat acaggcgaac aatctttagg aaaggaagaa gtaattaaaa atgccaagat
    60061 taaaggtttc tataaaaatt tggtagaaga aaaagatgct ttcttaatag attcaactaa
    60121 ttttgaaaaa cttgaagatg gaagttacat gtatgaaata aattcaaagg gtaaaaaccc
    60181 agaagtaagt caatatggta aaaatataaa aataaataaa aactatctta aagttaaccc
    60241 tatttactca aatggcaaag aaatatttaa tctaatcgat tatgacgata agactataaa
    60301 tttattagtt cctaaaaagt tacaagtaca tgaaaatgag attaaaaaag agtttagaga
    60361 attattttat tttgaaaaaa tagaagtaga aaatatgtac aataaagagt taaatagaga
    60421 gttaaataaa acaaagaagt ccgatttaaa tgttaatata atatatgtag ataataatca
    60481 aagctatttt acttataact cccttgttat ggatgacaat aggaatctca ttgatgaccc
    60541 aatagcaata gttgacatag ataatattga tgattctttt tatctttctt atatatctag
    60601 atgtgtatat tttaattcta agaaattaga tgcccttgca gatataagta gcattattga
    60661 agctcaaggt gtagaagcgc atatccaaag tttacatgct gtttataatg agtatggttt
    60721 agaaataaat aaactagaaa aatatttgaa tagtgaaatt tttactataa taataatagc
    60781 aatatcaaac ttaatgatta cctacaatat agtagctagc tactatgaaa gaaataaata
    60841 taagttatat attaaaaaaa tatttggtta ctcaactaca gctagaagta tgttgttaat
    60901 agtctcatta atattaacaa acattattcc aataggcatt atatcaacaa gagtagattt
    60961 aagtaataat attatcttat ttggacttct aatattagtt atagaagtaa ttgtatctat
    61021 tgtattagac aagattatct caaatagttc atttaataaa attataaaag gagaacatta
    61081 aaaagatgat ttcattaata aatatatcta aaaaatttaa agataaatct ataatagaca
    61141 aatttaacct agaaatttct aagggcgagt ttgtagcgat aacaggaaat agtggttcag
    61201 gtaagacaac tttacttaat ataatgggat tattagaaaa acctaattct ggtgatatta
    61261 taataaataa tataaaaaat ccaaatagta aacagataag aattttacaa agggattttt
    61321 atggctatct atttcaaaat tatgctttaa ttgagaatga aaatgttgaa aataacttga
    61381 aaattgcttt aaagtatcaa aaaaatatca atcataatga aaaaataaat tacgcacttg
    61441 agtctgtagg tcttagaaaa tacaataaaa aaaagatata cgaattgagt ggaggagaac
    61501 aacaaagggt agcattagca agagtaatat taaaagaatg tgaagtaata tttgcagatg
    61561 aacctacagg taatttagat aaaaaaaata gagacatagt atttgatata cttaaaagtc
    61621 taaataagaa tggtaaaact atcgtatttg taactcatga tttagattta tcggagcagg
    61681 cagatagagt tataaaattg taataatata aactataata aatataagaa agagattaca
    61741 gctaaattaa gtttaataat aatacgaata gaatttaaac attaagtaaa ttagtagttt
    61801 gtaaatataa gtataatatg atatcataaa ggctcaaaag aaattttata taataagaaa
    61861 tctaaaaata acaaatggag gacatataaa gatggaaaat ttaccaaatt gcccgaaatg
    61921 taattcagaa tatacttatg aagatggaac tcttttagtt tgtccagaat gctctcatga
    61981 gtgggcatta ggattgggag ctgaagaaga ttcaaatatt atcaaagatg taaatggaaa
    62041 tgtattaaat gatggagatt ctgttacagt aattagagac cttaaagtaa aaggaagttc
    62101 atcatctata aagattggaa caaaagtgaa aaatatccgt ttaatccatg actcatcaga
    62161 tggacatgat atagaatgta agatagatgg ttttggagct atgaagctaa agtcttctgt
    62221 tgttaaaaaa gcgtaatatt ataaataagc tgtagtgttt attgtttttc agtacagtat
    62281 aaaaccataa gaatctatta agtaataaaa gtttgtttat ttatctttat attttcttat
    62341 ggttttatta aatataaatt ttattgaaca ccaaaatatt ctctcctcta caaataagcc
    62401 aatcttattt aaactaatat actttgtact atttatactg aaattgtaaa tttaaatgct
    62461 atgttattta ggtttgtata gttaatttat atatttctga ttttataaat tgtatttatt
    62521 attatatctt gattctaaaa tcattaaaaa tttcaacttc tataaagatt tacaatttat
    62581 caaatacatt atgagtatat aaacaattta ttattacagt gctacattta aaataagtct
    62641 tagtataaag gtattgttac aagtataaag aaacttatgt atgctattgg aataaataat
    62701 accttaaatt ataattaaga ataagaactg ttaaataagg gacttgatta tcatttagtt
    62761 atagataata taatattaaa aataaagttt aagaggagaa aaaatatgat agatatacat
    62821 aaaaatatat atgataataa gttatttgag gagctaaaga ttgactgtaa gaagtgcttt
    62881 ggactttgct gtgtagctct ttatttttct gcttcagatg gatttcctat caataaggaa
    62941 tcaggaaaac cctgtattaa tttacaacca gattttaaat gttctgtaca taatagtctt
    63001 attaagcgag gttttaaagg gtgtactgca tatgattgtt ttggttcagg tcaaaaagta
    63061 gcacaagtaa catataaggg gatagactgg atgcaatcac cagaactaac aaatcaaatg
    63121 tctgaagtgt ttttaattat gagacaatta catgaaatgt tatggtatct taaagaagca
    63181 tctgtattaa atatatcaga tacaatcaaa tcaaaaattg atttaataat tgaagaaact
    63241 gaaaagataa ctaatatggg cccagaacag ataattaatt tggatatcat atcacataga
    63301 acaaaggtta atttattatt atcacaagcg agtgagtcta tgatgggaaa ggttaaatca
    63361 tttatcaaga cttctactct taaaaacatg aaaaaattaa gtaaaaatat agatttaata
    63421 ggagcagacc ttagaaaaat aaatctaata ggagcagatt taagaggtag atttctaata
    63481 gcagcaaatt taagaaatac agatttgagt ggggcaaatt taataggagc agacttaaga
    63541 gattgtgata ttagaggtgc taatcttgaa aatagtatat ttttaacaca attacaagta
    63601 aatactgcaa aaggagattc tagtacgaag ttaccagctt cactaatacg ccctaaatac
    63661 tgggaaaaat aattaaatta atacataatt ttacaaaata tgaacttttt tgactttaat
    63721 tcatattata cattagagat tctttacaag aatttcttaa tataatatag ggagagatat
    63781 aaaaatgagt tatcaaaatt ataaatgtga aagagattat gtgtatgatg attataaata
    63841 caataagtgc aacaagtgct ataatgatta tgaggaaatg acacatgttc atgaatattc
    63901 agaaagtgtt aagttagcag aagaatgtga ggatagacat aaccaccgtg cagcaggggt
    63961 tactggtgaa gttataccaa taaatggagg tacaaatcat gttcataaaa taaatgataa
    64021 tgtagatttc cttgaccatt tccataagat atgtgttaca acagggccag caattagaat
    64081 acctggaact gataaacaca ttcacttaat atgtggagaa actactgtta atgatggtca
    64141 ttgtcataaa ttccttttta ctactcaaat agaagcacct ttagtataag ctgatgtgaa
    64201 ttattgtagt gaatttgcta gattatagta taatatataa tagataatat ttaaacttaa
    64261 tgaggactat gatatttaac cttcgtagtc ctttctaagt tttgtataaa aaagtgttat
    64321 gcaattaaaa gtgatatagg gaggaaattt ttatgaaatc tggaataatt cttgaaatga
    64381 aacaaataaa ttcaacagaa tatgacgaaa tgttgcaagt ctgggaatca tcagtaagag
    64441 caacgcatga ttttttaaca gaaaaagata ttgaatcttt gataccatta gttgagattg
    64501 gacttaaaga agtagaaaat atagtttgta taaaagataa tgatataata aagggcttta
    64561 taggaataga taaagataaa attgagatgc tctttataga agataaatat agaggaaatg
    64621 gtattggtaa aaaattaata aaatatgcta tagataaata caatgtaaaa tatgttgatg
    64681 taaatgagca gaataaaaaa gctgtaggat tttatattca cttaggattt aaagtgtttg
    64741 ataggtctga aatagatgga caagggaacc catttccaat actacatatg aaattaattt
    64801 aaagttatac ttcccactta ttcgcaaaaa tatttactta aatttttata caaataaaag
    64861 tcgtgacagt cttaggacac gactttttta ctacactatt aaattgaaat ttatctgttc
    64921 tatattatga ttattagatg tagttttttt attttaacta tgtacttaaa taccaagtat
    64981 acccatacct atcaagtact tcagcagcgc catcattttg atgtggtggt gggtgtggta
    65041 aaaattcttg tacaagtgta ccaccttcgg caagttttac agatatttct tctatcgctt
    65101 ctcgagatgg tagaacaaca caaatcgcca tgccagaaat tacaacaggc ttgtctgtat
    65161 ccgcacccat tatacaacct tcgtattttg tgaaagtaac acttgcgtgc ataataggat
    65221 tgtttggatt gctgtctaat cgcgcaaata tagtttttcc tcctccgaaa gcctcagcat
    65281 aaaaattaaa tgctttttca caagtaccat taaatattaa atatggagtt agcatgacca
    65341 atatatcctc cttgatatag aataatttat agttgcacct gataatctaa attatgattt
    65401 agtaaattgt atcataggga aaccttgaag tatataattt tttattatta tattatacaa
    65461 atttattaat ttaaaaaaat gttatatgta cggaaggttt acaggataaa atataataaa
    65521 aagattaagg tgacattata aaaaatgtat attgacattg acgctacgta attgtatata
    65581 ctttgtctta aaggagatgg taaatatgaa tattatagaa attcgctcag ataaaatata
    65641 caagaagata atggatgcac caataaacaa aaaagaagat atatacagat atgaattaat
    65701 gaagcctttt gaatttaagt ggaagtgtat gaatgttcca atagttgcta gacagaaagg
    65761 tggatatgat gtaattatag caagtgaaat gttaggggtt ttatcgccta aggatattga
    65821 tgaaaagcaa aaaaagaata taaatgtgtt atctgctgat aaaatttggg gcacttgcaa
    65881 agaaaccata gaaaactcta taaatgcttt tataaaagaa gggtatgatt taaacattaa
    65941 ggactataaa tattcaatat tattggcgaa tccaaatagt ccttatacaa tattaagtga
    66001 tggatactgg ggtgatggtg ggattcctgg atatatattt ctatcattgg ttcctaatga
    66061 atatactatc aatagattac cagtattaat agcacatgaa tgtaatcaca atattagatt
    66121 tcagtttata gagtggaata ataatataac attagaagaa atgatgataa atgaaggtct
    66181 tgcagaaaat tttgcaacat ggatgtttgg agaggaaatg ttaggacctt gggtcagtag
    66241 aacagatatc gaaacattaa atacttatat aaagccaata ataaaaagtg ctttaaaaga
    66301 aactggattt caaaatataa catcttatct ttatggtgat gatatagcta aaatgcaagg
    66361 atattttcca gtagggttgc cttattgtgc aggatatgct tgtggatatt atatgattaa
    66421 gtattattta gaaaagacaa ataaatcaat aatcgaagcg actttattgc cttatagtga
    66481 gataatcgaa gcagtaaaag agttttggga ataaatttta taaattgcat aatttgaaat
    66541 aaattatgca attattttat ttttaagaaa aaataaattg acaataattt ataagaaata
    66601 tacaataata tatataaaga aatatttcaa tatttaaaag ttttaagatt tcatatctag
    66661 agtagctaac attacatgtt agtttcttgt tacttatcta attactttat atttcgtagt
    66721 tatatataaa attactataa aaaatgaaat atattaaaca atcaactgaa aaatgaaatg
    66781 ttaataaaaa aaaattcaaa ttataaatat taaatgaata taattaaaac aaatatataa
    66841 atttaagtat aacactcaca ttttaatgta ttgtgaaatt tttgttgaac tttatgtacc
    66901 ataacttata aaatttatgt catgttatat ttgaataagt aataaaattg tagatgtaaa
    66961 ttaatctaca aaatttatat gaaatggagt tgatgctatg acagaattaa tgattataag
    67021 tgggttagta ctattgattt gtataacttc tagcaaggta ttgtataaat ttggagtacc
    67081 aatattattg atttttatct tactagggat gttatttggg tctgatggga tggtaggaat
    67141 ctattttgat aactatgaac tgacaaaaca attatgttct attggactaa tatttataat
    67201 gttttttgga gggtttggaa caaactggaa tatggctaaa cctgttgcta taccttctat
    67261 attaatgtct tcactgggtg taataattac ggctggggtt acaggtatgt tttgccacat
    67321 ggtaatagga actagtttac ttgaaggttt attaattggg gcaattgcag cttcaacaga
    67381 tgctgcatct gtgtttgctg tgttgcgttc tcaaaaacta aacttaaagg gttcacttgc
    67441 atcattatta gaagttgaaa gtggaagtaa tgacccaata gcgtatatgc tgacactaat
    67501 tcttttgaca ttgatgaata attctggggt agaacttatt gcaccaatgg taataaaaca
    67561 aatagctttt gggttagcta taggatttat actagcaaaa ttatctgttt atattttaag
    67621 acattcaaac ttcgagatag aaggatttta tactatattt ataacagcta ttgcaatact
    67681 ttcttatgca tttagcgagt atcttggagg aaatggatat ttaagtgttt acatttcagg
    67741 tattattata ggaaatagta ggatacctct taaaaaaagt ttggttcatt tctttgatgg
    67801 aatttcatgg attatgcaaa taatgttatt ctttatgtta ggattgttat ctttcccttc
    67861 taagttacca aatgtatttg gtatagcaat ggccatatct atattcatga tagttattgc
    67921 aagaccatta gcaacattta tagttctagc aaaatttaaa ttctcaaata aagaaaaatt
    67981 attcatatcg tgggtaggtc ttagaggtgc ggcttcagta gtttttgcaa tttatgctgt
    68041 tactcaagga gtagccatag agaatgacat attccatata atatttttta tagcgttgct
    68101 ttcagtagga atacaaggtt cattgatacc aactgtagcc agaaagttgg atttagttga
    68161 tgataataca cctgtattaa aaacatttaa tgattatgat ggagaaatta gctctaaact
    68221 tatcgaagta aatgttgatg agggtaataa atgggctaat aagagtataa tagattctaa
    68281 tataccagac gatatattaa tagttatgat aaaaagaaag gaacaggttt taatacctaa
    68341 aggttcaacc attataaaaa caggggatat tttggtattg agtggagata gaattgaaga
    68401 attaatacaa ttataattta ttttgtattg actttaacct aaggggaaag tttaaactta
    68461 aattaatcaa atctaatgcg caggtgatga gatgttttct ataggaatgt tttctaaaat
    68521 aaataaaata actacaaaga cattaaggta ttatgaagat atagggttgt taaaaccaga
    68581 atatgtagat gaatttacaa aatataggta ttatacaaca gagcaattac ctaaattaca
    68641 tcagataata actttaaaac aaatgggttt atcattagct gagataaaaa aagctgtaga
    68701 aaatcctgaa gaagttgaaa atattttaat gaataaagaa aaagaaatgt tggatgtaat
    68761 taaaagtgaa gaatataaaa taattaaact acgtaattac cttatgaatt tgaaaggaga
    68821 agtcaatatg aatgatgtaa ttattaagtc tttaccaaaa gttaaagttg cttctatgag
    68881 aaaagtgtta aaggggtatg atgaactttt taatctattt ccaaatgtaa tggctgaaga
    68941 aatgatgaaa acagggtgta catgtgcagt tcctgattat tgttttaata tatatcatga
    69001 tggtgaatat agagagactg atatggatgt tgaaatgtgt caagctataa atgatttaaa
    69061 ggaagatacg gatatattaa aatttaaaga attagatgca gttgaaaatg cagtttgtat
    69121 attacacaat ggtccatatt caacattagg aaaaacttac gcagatgcat ttaaatggat
    69181 agaggataat aaatataaag tggttggaaa tcctagagaa tcttatatag atggtatatg
    69241 gaataaagag agtgaagaag actggttgac agaagttcag ataccagtga aacgcatgtt
    69301 ataatatgtc tacaaagtat aaataagaat aaaaaaggtg gtgtctcaaa gtaaacattt
    69361 tagtttatga gacactcttt ttcatatgaa atcaagtata tttttataat tacgattatg
    69421 aaaaaaggct tatctatatt tttagacagc ctcttatttt tttattataa tagttttcta
    69481 aagatgctct atttataaat ttttattaaa gactttataa ataattgtat ttaatataca
    69541 aaatatatat aaatattgat gttttatata taaagttgta tattttttta aggatataaa
    69601 gtaaaaaaat atacaatatc aagaaaaaaa gatattgggt atttaaagta atactttatt
    69661 taattttaag taaatcgggt atctacatat atagatacta atttcaaaga ataggagggt
    69721 gtttatatgg aaatattcgc aataggacat tcaaattatc catatgataa gcttattaat
    69781 atgataaaaa aatatgacat aaattgtgta gttgacatta gagaaactcc atattctaaa
    69841 tataatattc aatacaataa agaggcattt aacgaatctc ttagaaattc cggattttta
    69901 tatatataca tgggaaaaga atttggagct aaaagaacta ataaagatgt atatacgcaa
    69961 gaaggttatg cagattttga gaaagtagca aaagaagata tttttttaaa cggaatagaa
    70021 agattaaaaa agggttgtca aatgggttat aggatagttt tattaggagc tatgcaagaa
    70081 cctataagat gtcatagaag tatcttggtg ggaaaagtat taaataaaga aggttttgat
    70141 gtaaaatata taatgcatga aggaaatttg gcatatcagg aagatataga ggaatcatta
    70201 ttggataagt attttagtga tagaaagcaa ctgagtattg acaatttatt agggagtgca
    70261 ttaacgagag aagaaatgat acaagaaggt tataagctag ctaataaaga aataggatat
    70321 agaactgaga aactaggtaa ataaaaatat acaaatagat aaaatacagt acttatctta
    70381 agtaaaataa tattatgaat ttataatagc taggcatgat gtgccaatta aaaatattct
    70441 agttatttaa taatatcatt aaatttaggg tattttttaa tagcacatca tgttgcagtt
    70501 ttaaaaaata aaatctctaa tattgccata atcaactgtt ctattaagag taggatgact
    70561 agatataaat ctaactgtaa tttttgaatt taacaaacaa ggatttgaaa ttaaaaatac
    70621 tctatctcca ttgacaatag aagtaatagc tactggcaaa atatctacaa atgtatcata
    70681 tctgttttta gcaatttgat aaggataatt tcctacaaaa acaaatagat ttaaatcata
    70741 tatattatca gtaaaccaag cccattgacc ataaactttg tcaatattca ttgtgcctaa
    70801 accaagtgta tcaaagtatg ttgctatagt taaataaata ttttccatgt tttctaaata
    70861 tgaaacagta tatcttctga aacgtatggg tgctgtggaa gaaataggat aaaccatatt
    70921 tacatttaga ttatttgcat ttaaattaac caaagtatca catcctaaaa ttagtctata
    70981 aaatacaata tttaaatgga tgcgattttg ttacatctaa agtgtaatat tttatatatt
    71041 gaaaaagtgg taaaagtttg gatgattaaa taatattata aaaaatatat aaaatgtact
    71101 tattgttatt gctacacgat agtgatacaa tattaacgaa atatagctac ttttaataat
    71161 aacggaaaat atttatatta aattaataaa tattttaaat gtggtatcca taaaaaataa
    71221 taaacataag ataattataa agatatactg tgttcaaatg atattaaaca agatttatat
    71281 tatttgaaag cagtatatta taatgcgaac aatacaattc taaactttgc attgtcaatt
    71341 tacagttcga taaactaatt aaaaattaaa tttatataaa gagggaaaag aggaataggg
    71401 atgtttataa ggaaaaatgt tataaagtta gcaattccta taatgataga gcagacgttt
    71461 gtcatgcttt taggagtatt taatacaatg atggcaggtc atattgggga agaagctgta
    71521 tctgcagttg gaatggttga ttcaataaac aatatattta tatctgtatt tgctgcacta
    71581 tctgttggag ctactgttgt tgtagctcaa caaataggaa aaaaagatag tgaaaaggtg
    71641 aatgaaacta ttaagcaggc tctagtgtct ggagtaatat tatcctttac aataacaata
    71701 ttgatgtggg tttttagaac tggtgtaatt aatttatttt atggttccgc agaagaattg
    71761 gtaaaatcaa atgcaaaatt atacatagag tttacattat ttacgtatcc atttattgcg
    71821 acacaacaaa tagcaaatgg tattttaaga gggtgtggag atgtaaagaa acctatgtat
    71881 gtgactatgt ttatgaatat agtaaatgta acattgggat atatacttat atatggtatt
    71941 gatttaaatc ctctaggaat aaatttgcaa acaccatcct atggcataac aggtgcagct
    72001 atatctattg ctatagctag aataattgga tgtatagtaa ttataagagc tttatttaaa
    72061 ggaaacgaat ttatatctat gggtaaaata tttccattta agattgatgt tgaaactcaa
    72121 aagtctatat ttaatatagg aataccagct ggagttgaac aactactttt taatgcaggt
    72181 aaattgattg ttcaagtatt tatagttact atgggaacat cagcaattgc atccaatgca
    72241 ataggaatgt caattgcatc cataataaat gtaattggga atgctttagc tttgtctgct
    72301 acaaccttgg tgggacagta tataggacgt ggagatatta aaggagctaa gagtacttta
    72361 ttatatttaa ctaaatttgc aacaatttgt ttatttatag taggagctat atttatacca
    72421 attgcaccct ggatttcaag tatgtatact caaaatgcta gtgtaattga catctcaaca
    72481 caattaattc gaagtgattg tttagctatg gtaatatggc ctatatcctt tgtattatca
    72541 gcagggctaa agggagccgg tgatactaga tatacaatga tgactgcagt aataggtatg
    72601 tggattttta gaatttttac aggttacgta ttgggggttg tattagaatt tggagtgtta
    72661 ggaatttgga taggtatgta tactgattgg cttgttagag ggactttata ttgtttaaga
    72721 ttaagaggaa caaagtggct aaaacacaaa gttgcataga atatatgaaa tcacttttag
    72781 atggataact ctatttagaa gtgatttttt atgtagttat tatcataatt ataagtatga
    72841 tatataaggt gattaaatta cataaataaa ggctataata gtatggatat tataaattat
    72901 atattgagca gaattacata atttggcgat aaatattaga aatatatatc tatagaaaat
    72961 aatatatatg ggtatattat taaatataaa aaatattagg tatttattta ataataaagg
    73021 tgggtattgt tatgataaat aaaataggaa aaataactct ctatgtaaat aatcaagagg
    73081 atgcaaagtt attttggaca gaaaaattga actttgtagt aacttatgaa aaggaaatgg
    73141 gtccaaatat gaaatgggtg gaagtagcac caagtaaaaa tgaatttaca acatttgtgt
    73201 tgtatgataa aaatctaatg atgaagcaaa acaaagagat aaatgtatct catccatcaa
    73261 taattttaag tacaagagat attaatggaa cttatgaaca aatggcaaat aacgaggttg
    73321 aggttgggga attaatggag atgccatatg gaaggatgtt ttcttttaaa gaccaagatg
    73381 gaaatgatta tttggtcaga gaggataaat aattttacaa agtattaaat ttactcaata
    73441 tctgatataa ttagagacaa taattattat aaactagtct aggattagaa ttatataatt
    73501 aaaaattaag tgtaaatttt gagtagaggt gataaaatgt ttaagaaaat ggcagtacta
    73561 aaagatatag caactaaaat aggtcgtaaa aaagcgtatg aactattaga aatggttgaa
    73621 ggtaatgatg cctttgtagc tgaggtaaag ataaaaaaga atggaataga atctaaaaaa
    73681 gaagaaatta tgttaaaaga taatcaaaaa ataatattag agtatataga aggttaaatt
    73741 ttaaatacat ataagttgat atactaaatt tctgagatga gtttacataa aactcatctt
    73801 ttttactttt caataacttt gttttattat ttaatataca ttttatctcc ttagagttgc
    73861 tgatatataa aaattactga tataataaaa gaatggatat taatgtaata ttttatagaa
    73921 aagaggggta ttatgcttga aataaaaaat ctttccttta atgttgagtc taacaatgag
    73981 gaactaggaa taataaatga tgttagcctt tcatttgaga ggggaaaact tattgttatc
    74041 acaggtccaa atggtggagg aaaatctaca attgctaagc ttattatggg aattgaaaaa
    74101 gctacgagtg gtcagataat tttagatgga gaagatataa caaatcttag tattacagaa
    74161 agagcaaaaa aaggaatagg atacgcattt caacaaccac caagaataaa aggtatgaca
    74221 gttgaaaatt tacttacact tgctcatgga aaaccattgt ctactgatgt atgttgccaa
    74281 taccttacag atgttggatt gtgttcaaaa gactatttaa atcgtgaagt tgataactct
    74341 ctttctggag gggaaatgaa aagaattgag atagcaactc tttttgctag agatttaaag
    74401 gtttctatat ttgatgaacc tgaagcaggg atagaccttt ggagctttgg aaaactcaat
    74461 gaaagtttta agaaaataca tgaagagtct aatcagacta taatcataat ttctcaccaa
    74521 gaaagaatat tagagttagc tgatgaaata attgttctac aagatggttc agtaaaaagc
    74581 catggaacaa aagaggctat attacctgaa atcatgtgtc aagttaattc aagttgtgaa
    74641 ttaatgaaag acatgaatta attagaaagg aaggcaaatt aaatgaacaa aatagattta
    74701 aatcttttag aaaaagttgc tgaacttcgt ggaactccat taggagcata caatatacgt
    74761 aaaaatgggc aaggagtaga gagacattca actgaaaatg taactataat tcctaaaact
    74821 gataaacctg gaatagatat tatagtaaag ccaaatacaa aaggagaaaa tgtacatata
    74881 ccagtaatag taacagaggc tggtgtacag gatatggtat ataatgattt tgaaattgga
    74941 gaaaatgcag atgttgttat aattgctggg tgtggtatac ataactgtgg ttgtgatgat
    75001 agtgaacata atggtataca tagatttttc ttacgtaaag gagctcgact aaaatatgta
    75061 gaaaaacatt atggtgaagg tgatggagaa ggaaagagaa ttttaaatcc agttactatt
    75121 gtcaatatgg atgaggattc atattgtgaa atggaaacaa ttcaaattaa gggtgtagat
    75181 tcaactaaaa gagaaatgga tgcaaaccta ggtaaaggag ctaaaatagt tgtatttgag
    75241 aaattattaa ctcatggtaa tcaagttgca gaatctaata tgaaggttat cttagagggt
    75301 gaaaactctt ctgctcaagt agtttctcgt acagttgggc aagataattc taagcaaaag
    75361 tttaatcctt gtgttattgg ggattccctt tgttctgcac atgttcaatg tgattcaata
    75421 attatgggaa attctcaaat tagtgctata cctgaaattg ctgcaaatca tccagatgct
    75481 cttttagtac atgaagcagc tattggaaag attgcaggag accaaatact aaagatgatg
    75541 acattaggtc ttactgaaga agaagccgag caacaaatac ttaattgctt cttaaagtaa
    75601 attaaagatt ttatttaatt taatataatt aatatagtat aatatagtga ataagtctaa
    75661 aatattttta tttttaggct tattttcttt atgtaagaaa agctattaga gaaattatat
    75721 tgtaattagg atgtggaata aatgaaaaat ttacttataa gaaatgggac aataatatct
    75781 ccaacagatg gtatcaaatt tgaaaaaaga gatatcttgg ttttacatgg gaaaatatat
    75841 gctattggat tgaaccttaa agagaaaata agaaaagaaa aattacttac aaataaagag
    75901 ttcgagataa taaatgccga taatatgtat atttccccag gatttataga tgttcacacc
    75961 cattgttata agagaaaatt acctacaggt atggattctg attcaattgg aattgaaaaa
    76021 ggttctacag ttatatttga tgcaggtaca gctggtccct caaactacta tgattttaaa
    76081 aaaaagtata tggatgagtg taaaacagaa gtatattctt ttttaaatgt tacaaatgag
    76141 ggactaaata tattgaatga atcaacttat ttagatgtta taaattttga caaggttgag
    76201 tcaattgtag aaaaaaatat agaaaagata aagggtataa aagtaaaagc gagtaaattt
    76261 caatctaatg aaagtggtat agatataatt aagaaatcaa agcaagttgc taaaaaatta
    76321 aatttaccct tagtggtata tataggagag tatccatcat atatagatga agtaatgaat
    76381 attttgggaa aaggagatgt ggttacaccg gtatatggaa atagtacaaa tggaatcctt
    76441 aaagaatctg gcacattaag aaaatcagta ataaatgcaa agaatagagg agtattgttt
    76501 gatgtatgtc atggagtgga ccaatttgat tttaaagttt ttaaaaaagc aataaagcaa
    76561 ggtttagagc ctgacctaat aagtactgat atgcatataa aaaacatgaa agacgtaaac
    76621 tattctcttt taaatgttat aaataaaatt atggaacttg ggatatccct agaaaagtgt
    76681 atagaaaaag taactgaata cccaacaaag attttcgatt tacatggaaa taaaggcaga
    76741 ataaagattg gtggagaagg tgattttaca atatttacaa tggaggagtg taatgatatt
    76801 ataaaagact acaataataa tgaacttgtt ttaaataaaa aattaagatt gcaatatact
    76861 gtaaaatcat ggatgaaaag cagtgaagtt tatagacatg gatacgaaaa tactataata
    76921 aactaaacaa tagtgataaa ataataaata tatgtttaaa ttggtatata ttggataaat
    76981 atctaaggaa acaacaatta aaaaataata attttagggg aggtatttta gtatgaaagc
    77041 atttgttgat aaggatgtat gtgtagcttg tggagcatgt ataggaacat gtccagacgt
    77101 ttttagtatg agcgatgaag ggcattcagt agcaattgaa ggagaaatac cagcagattt
    77161 acaagattta tgtaaagaag ccgaagaagg atgtccagtt tcagctataa cagttaaata
    77221 gagctgttta aatttatttt taaaataaat atataagatt taattggtac ttaagctata
    77281 gtattagaaa tttctattac tatagctttt taaaatagat aaacttaata tataagatat
    77341 tactttttac aaatatggag gactgaaata tgaaaaaaaa ttatgaaata gtattattcg
    77401 atttagatgg aacacttaca gaccctaaag aaggaataac aaagtctatt cagtattctt
    77461 taaatagctt tggcataaaa gaagatttgg aaaacttaga ccaatttata ggaccaccat
    77521 tacatgatac tttcaaggag tattataaat ttgaagataa aaaagctaaa gaagctgttg
    77581 aaaagtatag agaatatttt gctgataaag ggatatttga aaataaaatt tatgagaata
    77641 tgaaagagat attagaaatg ctctataaaa atggtaaaat attattagta gcaacttcta
    77701 agccaacagt ttttgcagaa actatactta gatattttga tatagataga tattttaaat
    77761 atatagcagg tagcaatctt gatggtacaa gagtgaataa aaatgaagtt atacaatatg
    77821 tactagacct atgtaatgta aaagataaag ataaagttat tatggttgga gatagaaagt
    77881 atgacataat tggagctaaa aaaataggta tagattctat tggagtattg tatgggtatg
    77941 gttcttttga agagattagt gaaagtgaac ctacttatat tgtcgaaaat gtagagtcta
    78001 taaaagatat tttgttataa atatctttta tagacaaaaa tattacaaaa tggtgtcgca
    78061 tatttaaaaa tatgatatta tagttaagga agtcatttaa aaaagaggag gatgcactta
    78121 aaatgaaatc tattttaatt atgggtggaa gcgacttcat aggttctgca cttgctaagc
    78181 gcttgattaa atgtgggtat caaattgata tacttacaaa tggtaaaaag gaaatagatt
    78241 ataatggttt taaagaacat ctaatttgtg atagaaaagt tcgaaaagat atggaaaaca
    78301 ttatcacagg aagaaaatat gattacatat atgatatgac agcatataca aaagaagatg
    78361 taagtaatct gattgatttt ataagcatgg ataacttaaa aaagtatata gtattgtcag
    78421 caggagcagt atataaagat agtggaagaa atataaaaga agaaaatgag aaaggtgaaa
    78481 atgaaaactg gggaaaatat gggttaaata aaaaagaggc tgaagatttt attataaata
    78541 gccctatacc atatataatt attagaccaa cttacatata tggtgaaaat aataatttat
    78601 atagagagta ttatttcttt gaaaaaatag aaaaaaatga aaagatacca gtaccaaaag
    78661 gaaaacaagt tagtaatcaa tttatatata ttggggattt ggtaaaggta ttggaaagca
    78721 taatgaaaaa tcctcatgta agagaggcct ataatgtgac aaatccacag ttaatttctt
    78781 gggatgacct tatatataca tgtggagaaa ttattggcaa agaacctata ataaaatatg
    78841 tagatatgga aaaagtagag tttagagaaa gaacgtattt cccatttaga aatatagact
    78901 ttaatcttga tataaataag cttattgaac atgggcttta tataccaaac gtgttactaa
    78961 aagaaggtct tacagcaaca tataaatggt tttcagcaaa taagccaaaa atgcatgaca
    79021 gaaaaatgaa caaagttgag tctgtaatgc aaatagttta aaaaaataaa taagtaggta
    79081 gatattttga actcaaaaat taagtatttt ttaaaatttt ttatcttaat atttattttg
    79141 atttttatat actcagttgc gatagagccg agtctattaa ttgtgaaaaa atataatata
    79201 agtgaaaatg gagcattgat aaaaaatgat tcaattgaga gtaaatctga aagtgtaaaa
    79261 gtagttcaaa tttcagatac tcaaataggt agtttttatt caactaagaa tctcaaaaaa
    79321 gtagctaata agattaacac tttgaatcca gatataatag tatttactgg tgatttaatt
    79381 gattactcca ataaaaatcc aagtgtagat gaaattacaa ctattttatc aagtatgaat
    79441 gctaggttgg gaaaattttc agtatttggc aatcatgatt atatgtataa acttcctagg
    79501 tattataggc agattatgaa aaattccaac ttcaatcttt tagtaaatga aaataaaaaa
    79561 ataaaattaa aagatgataa atatattaat atattaggtg ttgatgaaat attaaatgga
    79621 aatcctaata taaaatatct ggagagtcaa atagataata aaagttttaa tttattgtta
    79681 gcacatgaac cagatttagt agatatgctt agtaaagata caatgaattt agttctatct
    79741 gggcatagtc atggtggtca aataagatta cctattaagg gagcattagt tactcctcca
    79801 tatggaagga aatatactaa agggttttat gacataaatg gaaatcattt atatgtgagt
    79861 tcgggtcttg gaagtacaaa gttaccattt agatttttta atataccaga gataatagaa
    79921 tttaatatta taatctaaca taaaatattt agaaaatata attttgcttt ttataatatg
    79981 tagatgtata tactgtaaaa atggattaaa ccagtagatt gaatgaatta atagattaaa
    80041 ttaatatata aaatatttaa gttataatta atgtattaga caaaataaat actattaaga
    80101 actattaaaa tatagattaa agataataac atataataaa taaaaaagta agattgtgta
    80161 gattatataa agattattta caattaatac aatcttgctt ttttatttaa aaattttaat
    80221 tattatttaa aattttttat cttctcttta tcccatataa acaatttctc agaattattt
    80281 aaagcaccaa atacatttct tttaaaatca ggcatctctt tatttaaatt agcaataaga
    80341 ttttttatgt actctctcct agtatgacca tttgcagggc agggatttgt gataatagga
    80401 tagttagaat cttttgaaat tttcttagtc atatactctt ctatgtaaac cataggtctt
    80461 ataactgtta aatcctgtct gtctaggtat gtctttgggg aaaaacaatt tactctaccc
    80521 tcataaaaca tagacattaa aaatgtctca attgcatcat ctttatgatg accaagagct
    80581 actttattac atccaagttt tttagcatta tcgttcaaag cacctcttct taaattagca
    80641 cacaatgcac aaggattctt ttcttgtctt atatcaaata caatttcttt tatgtcagtt
    80701 tgaaattcat aaaaaggaac atttatttct ttacacaatt tatctagtgg agaattatca
    80761 acacctccag tatttaatgt tatggctatc aattcaaagt tttgtggaga aaatctttga
    80821 taacttttaa gtatatgaag tagagttaaa ctatcttttc caccagaaag tccaaccgca
    80881 attttatcat tttcttgtat catatcaaaa tcttgtatag ccttacgagc tttacttaga
    80941 agtttttgta tagacatttt atcaccatcc tttaaaaata ttaaatttaa gatttattta
    81001 agatttactt ataaaatact taagtcttat actctaaaat taacattata gcaaacataa
    81061 caaaaaggag aagatttaat tatgaaaaaa tttaaattaa taggagccat tattttagta
    81121 gtatttataa gtgtatttat atctaaagat agattactta agaaagataa agatccaata
    81181 gtagctgctc aacatgattc agaacaagat gttgaggcaa attctcaaaa taaaaatcac
    81241 tcaaatagta tatcaaatat attattggta aacaagacaa atggaattag caaaaactat
    81301 actcctgaaa atattactaa ggtaaacata ccttttgttg aagaagcaac agaggaagaa
    81361 aaacaaatgg caggagaacc tgcaaaggca gttgaagatt tagttaagca agctaattca
    81421 gaaggaatac agtttttagg gtcttcagca tacagatctt atgatactca actggatact
    81481 tatacaagaa gggtaaaatc tcaggggcga gaaaaggcag atgcgtatgt agcaaagcct
    81541 ggttacagtg agcaccaaac tggactttgt attgatttaa caaatccaga aagatggttt
    81601 gttggaagta caaaagaagc taaatggttg gcagaaaatg ctcacaagtt tggatttata
    81661 ataagatatc ctgaaggtaa agaagatata acaggtacag catatgaacc atggcatatt
    81721 agatatgttg gtaaggatgc tgccgaggaa atttattcaa aaggattaac tttagaagaa
    81781 tatttacaaa ataaataata taaatgtgta aataatttgt attatattgg aaatttagaa
    81841 attaataaat ttatagatta cactaactaa aatatagtat aattttatat gaataaagct
    81901 atatacaaag attaagttag gatgtgtaaa aatgaataat acagttcttg ttgtggatga
    81961 tgaaaaggaa ataagagacc ttatagagat atatctttta aatagtggat ataatgtaat
    82021 taaagctgaa gatggaaaag aggctctaga tattttaaaa aaggaaaata ttcatttaat
    82081 gatattggat ataatgatgc ctaaaatgga tgggatagaa gtttgtagaa aagttagaga
    82141 aagtttgaat ataccaatac ttatgttaag tgcaaaatca gaagacatgg ataaaataca
    82201 agggataatg actggtgcag atgattattt gacaaaacca tttaacccac ttgaacttac
    82261 tgtgagagtg aagtcgctga ttagaagagc atattatttt agtggtgcta ataatgaaga
    82321 taaagatgtc ataaaggttg gagtagtaat tatagataag gaaaaacata gtgtaacagt
    82381 ggctggaaat gaaataattt tgacatcaag agaatttgat atattatatt tactagcaaa
    82441 taataaaggc agagtatata gtacagaaga aatatttgaa aaggtatgga aagagaaata
    82501 ttaccaatct aataatactg taatggttca tatgagcaga ataagggata aaattgaaaa
    82561 atatacagat ggagaaaaaa taattcatac tgtatgggga gtaggatata aaattgaaaa
    82621 ataaaagttt attaaatcat atgtttcgac ccatattaga tcttataata agctgtgctt
    82681 taacttcaat gcttatttta acaagtatgt atataataaa atcattatat gtcaatagtg
    82741 atatgtctgt agttaatcaa cttgtatatc aagcaagaga tttcagaagt cttatagggt
    82801 atgatttatt ttatccattt ttatttacaa tcacatcatt agcaatttat tccatgatat
    82861 cgtacaagag aaataagcaa attgtagatt ttataagaaa gactaataga aaaaatcaaa
    82921 aattagaaat cattaaaagt gctgtaaatt taatggatga aggtaactta gaaaaaagta
    82981 tagatattga gtatgattta gatatattaa aggataaaga aaaggatgat attgatgaac
    83041 tagcacataa aatcaataat atagtccatc aacttagaaa tataactatt gaagagagac
    83101 aagctcagca gacaaaaaca gatttaataa caaatgtgtc acatgactta agaacacctt
    83161 tgacatccat aatgggttat ttaggagtga tagaagaagg taagtataaa gatgaagttc
    83221 agatgatgta ttatgttgat attgcatatg aaaaatcgaa aaatttaaat gttcttataa
    83281 atgatttgtt tgaattgact aaaatgcaaa ataatacaat aaaattaaac aaaatagaaa
    83341 taaatttagt agagttatta agtcaagtag tatctcaatt tgaaatttat tttaaacaag
    83401 aatttatggt tagtagaatt aattttaatg aagaaaaatt aattgtaaaa gctgatccaa
    83461 ataaattggt aagagcattt gaaaatctta taactaatgc tgtgaaatat ggaaaagatg
    83521 ggcattatgt agatatagtc acagagaaaa aggaagatat ggcggttgta aaagtgataa
    83581 attatgggga accaattcca gtgttagatt taccaaatat atttgataga ttttatagag
    83641 ttgaaaaatc gagaaataga aatgttggag gttctggatt gggtcttgcg attacaaaaa
    83701 atattgtaaa tttacatgat ggagaaatta ctgtttcaag cgataaatat caaactgtgt
    83761 ttgaagtaca actgccaata atacaatcag cttagttata aaataaaagt acgattatgt
    83821 gatataaata ttataacaat aaagtgttta caaaaataaa aaagtaatat ataatttaag
    83881 tcagtttaat aagatactta tcaagagtta ggggagagag ttagctcagt gatcctatac
    83941 caacctttta tcaggtggtc ctgctaacaa cgatgagatg acttgaaata atatactctt
    84001 cttatcaata atagatagga agagtttttt ttagaattaa tgtaacaaat tttaaagtat
    84061 aatggaggat taaataatgg aaaaagtaga aagttttaag ctagaccata caaaagtaaa
    84121 agctcctttt gtaagaaagt gtagtgtact tgatggagta aagggagata aagtaactaa
    84181 atttgacttg agatttttac agccaaatgt agaaagtttt ggaactgctg ctatgcacgg
    84241 tttagagcat cttttagcta cttatttaag agatacatta gatggtgtaa tagacttatc
    84301 tccaatggga tgtagaacag gattttattt aatactatgg ggagatgtag atgccaaaac
    84361 agttaagatt ggtttagaag aagcattaaa aaaagttctt gaatcagata aaatgccagc
    84421 agctacagct atagaatgtg gaaactacag agacttatct ttatttgggg caaaggaata
    84481 tgcaaaagat gttttagata aaggattttc tttaaatata tatggagaat aatttaattg
    84541 gaagagaaga tataagcata aatcaaagtg aagttttaag atatttacaa tatagaggtc
    84601 aagagataga taaagacctt aaatatacta ttgatgaatg tgtagctata actaaaaata
    84661 aaataaatcc tagatattta tctaggattt atcctattaa aataaataaa gataatgttg
    84721 tagaattaga gggaacaaat ttaacattag agagtaaaga tgtatatgaa cttttaaaag
    84781 aatgtaatga gtgtgtaatt atggcagcta ctatagggat agatatagaa aaagaaataa
    84841 gacgacactc ttattcaaat ttaacaaaag gactaataat tgattcatgt ggaacaacag
    84901 caatagaaga agtgtgtgac attgttcaaa ataatttaga aaaggttttt ttaaagcaag
    84961 ataaatttat aactatgcga tatagcccag gatatggaga tttaccaata gaaaaaaata
    85021 tagatatatt aaacgttttg aatgctcaaa aacaaatagg tctaacaatt acttctaatg
    85081 gaattatgat accgagaaag tcagtagtgg ctattatagg tatttctaat acaagaataa
    85141 ataaatctaa gaaagaaaag tcgtgtgaaa attgtaaaaa ctatagaaac tgtacatata
    85201 gaaaaggagc gaactcttgt ggaaataaga caatatctga aaaataatat attaatattt
    85261 gatggtgcaa tgggaacaat gcttcaacaa aaagggttaa agttaggtga aaatccagaa
    85321 gtatttggtc ttcaaaatcc agataaactt atagaaatac atacagcata cttagaggca
    85381 ggttcgaatg taattcttac aaatactttt ggatgtaatg aactaaaatt agatagtaag
    85441 tatactgtag aagaagtgat tgacaatgct gttttggtgg ctagaaaagc tatagaaaat
    85501 gtagataata ctaaaccaag atatgtagct ttagatattg gtcctatagg agaaatgcta
    85561 gagcctatgg gtactttaag ttttgataaa gcatatgaaa tatttaaaag acaagtacta
    85621 caaggcgtta aatctggagt tgatgtaata gtaatagaga ctatgatgga tttatatgaa
    85681 gctaaagtag ctgtattagc agcaaaagaa aactctgatt tacctatttt ctgtactatg
    85741 acatttgatg aaggtggaag aagttttact ggatgtatgc cagaatgtat ggtggctact
    85801 atagaaggtc taggtgtaga tgcaatagga gttaattgtt cattaggacc taaacaactt
    85861 ttaccaatag ttgaaaaaat agcatcaaga gctacagtcc ctgttatggt tcaagcaaat
    85921 gcaggtcttc caaatatagt tgatggagag gctatatatg atgttgatgc aaaagaattt
    85981 tttgaagggg ttaaaaagtt cgttgaagtt ggtgctacta taataggtgg atgttgtggt
    86041 acgaatccaa gttttataaa agaaatatct gagaatataa attctgttac aaagggatgt
    86101 atcgagaaaa ttgataaatg tgtagtctgt tcaccatcaa aatttgtgga agtacaatcg
    86161 cctacagttg ttggagaaag attgaatccc acaggtagaa aatctctaca agaagcatta
    86221 aaaaatgaaa atgttgatta tgctataaat ttaggtttag aacaagtaaa tgctggagca
    86281 caaatacttg gagtaaatgt tggtcttcca gagattgatg aaaaaaaact aatgccaaaa
    86341 ttaataagag agattcaagc agtagtagat acacctttac aagttgattc ttccaatgta
    86401 gaggccttag agcaaggact tagatattat aatggtagaa caatagtaaa ctctgtaaat
    86461 ggcaaagagg agtctttaga aagtatatta ccaatagtta aaaagtatgg ttcatgtgtg
    86521 gttggactta cacttgatga aaaggggata cctaaaaagg ctgaagaaag atttgaaata
    86581 gcaaaaagga tagttaatag agcagtttct tatgggataa aaccaaaaga tatatttata
    86641 gactgtttat cattaactgt ttcagcacaa caagaagaag caatagaaac tataaaagct
    86701 ataacaatgg taaagacact aggagtaaaa actatattag gtgtttcaaa tatttcattt
    86761 ggtcttccaa ataggaaagc acttaatgct tcttttctaa cattagcttt aggggcaggg
    86821 cttgatttag caattataaa tccaaatgaa tatagtatga tggaagctat caattctttt
    86881 aaaatattaa ataacacaga taaaggatgt ataaactata taaatcaata tagcaatata
    86941 aataattcaa aaaaatcgga ttcatctaca aagattgata aagatttgcc cttggatatt
    87001 ttagttgaaa gaggattaaa agatgaagca aaaaatgtaa cactgaatct tttaaaagag
    87061 aaggatgaaa attatatatt agatgagatt ttaattcctg ctcttgataa agtaggaaaa
    87121 agatatgata gtggagatat atttttacca caattgattc aatcagcaga aacggtaaaa
    87181 gtttcattaa atacaataaa ggaaacttta ttaagtaaaa gtagcaataa tgtatccaaa
    87241 ggaaaaataa tagttgctac agtaaaaggt gatatccatg atattgggaa aaatatagta
    87301 aaaataatgc tagaaaatta tggatatgaa gttatagatt taggtaaaga tgtccctatt
    87361 gaagaagtag tggaagttgc taaaaagaga aatataaaat tagtaggatt aagtgcactt
    87421 atgactacga ctgttcaaag tatgaaagat acaattcagg cactgagaga taatgagata
    87481 aatgcaaagg tatttgtagg aggtgcagtt ttgacagaag aatacgctga agaaatgggt
    87541 gctgattatt attcaaagga tgcaaagtct gctgttgaaa tagcaaagtt aaatttttag
    87601 catataaatt aaaataaagg ttttactaaa taggatattt tatatataat ataaatataa
    87661 gttttagata cttatgttta aaacaatagg aattaatcta taataatgag attaattaat
    87721 ataaaaaata tttatcatca acattaaaaa gggctgggaa gtctggtata acttccatca
    87781 gcccttttta gttaaaatca tatgttaaaa agcccaatta ccatttttaa aaatctgtat
    87841 ttgctttcca tcataagtct caccaataat atccatatca gcagaaccaa tcataaaatc
    87901 tacatgtgtt aaactgtcat ttacaccatg ttcatctaat tcttcatctt ttaaattgtt
    87961 tccaccttcc agacaagtct tataagcaga accaattgca aagtggcaag aagcattttc
    88021 atcatataga gtattataaa aaattatatc cgtattggat attggtgagt tgtatggaac
    88081 aagagcaact tctcctaaat aatgagagcc ttcatccgtt tcaataagtt tttctagtgt
    88141 atctagtccc ttttcagcag agaaatctat tattttacca tctttaaatg ttaagaagaa
    88201 attgtcaatt atgtttccac cataaacaag aggttttgta ctataaacag ttccatttac
    88261 tttaaactta tgtggcattc caaaaatctc ttcagttgga atattcggat taaaacttat
    88321 tccattaggg tctttggatg ctccacttag ccaaacatga ccctttggca agtctagagt
    88381 caaatcagtt tttgaggatt tatattttaa agttttaaag ttatttttat ttagaaagtc
    88441 cattttagat ttaagatttt cattatgttc ttcccatgct tttatagggt cctgaccatc
    88501 tactcttgaa catttaaata tagcatccca cagtttttct attgctttat cttctgataa
    88561 atttggaaac actttttttg cccaatcttt tgttggcaca gagactatac tccatttaca
    88621 tttatcagtt agagtgtaag aacgccattc ttttaaagct tttccagatg ccttctgaaa
    88681 atttgcaact ctttcagggt caacatcttt taataaatct ggattttggg catagactga
    88741 taaaaatgcc ccaccttctt ttgctatatc tacatattgt tctgctgtcc atttggggaa
    88801 ctcatgaaat gcttcatctg gagcatataa gtatttaata agagtacttt cttcatcaga
    88861 ccactctata taaacatttt tagcaccaca tttatatgct tctttaagtg catttcttgc
    88921 aaaatcagca cattctattg gtgactttat aagtagaatt tgacctggct gtatgttaac
    88981 tccaactttt attgctaatt cagcgtattt ttctaaattt ctatttaaat tcatatttat
    89041 cctcctatat ttttaatatt gaataactta taaagtatta taacattact tatgttttta
    89101 atattgaaca acttataaaa tattataact ttacttagat tttgggtcat attcaaaata
    89161 tttatacttt atagattgag aaataaaaaa aatattttaa ttaaaacaaa ttatgaggat
    89221 aacaaactta tttaagtagt atgttttttg ttgataataa tattaaagta gaaataaaaa
    89281 tactttttta gtgaaaagct atacaagaat accgaaaaaa acttataata taataatgag
    89341 atagatattt ataaatgaaa aaaaattttt ctggcaaagc ttaattaaaa aggtaatagc
    89401 tagtgttgtt atttaaatta gcatagaaaa tcaaataaaa aaattatgct aatgtataga
    89461 cattgataag gtagaattta agccttttga atgctatatt aaactagagt agatattctt
    89521 atgaatttca aaatagggca ggaggaaaaa ggaaataaaa ctataaaaaa tataaagtat
    89581 ttatataaat ttatagagtt tatacgtcag aagatttcag ttaggagggc ataaatggag
    89641 ctttatgaag ccatttttta tagaaaatct gtaagaaatt tttccagtaa aaagataaaa
    89701 aagccattga tggaagaaat aaaaagaagt tgtaaaaatt tagaatactt aaatgaagat
    89761 ttaaatatta aagcacatgt tgttgataga ggtcatataa tacatttttt gatggggaag
    89821 gaatgtaaag taaaggcacc tcattatata gtagttacat cagacaaagg tgaggactat
    89881 ttacagaata taggatttgc tacagaaggt gtagttttgc gccttacaac attgggaata
    89941 gctacttgct ggttggaagg aaacttaaag agagaagata tcttggaatt tgtagatatt
    90001 gggaataaga attttgaaga agatgaggaa gatgatttag attatctagc tggaataaaa
    90061 acagaagaag atgatgaaaa caaaatagaa aatccttata taataatagc atttggatat
    90121 ccagcaaaaa atgaagagtt gtttaggacg agatatgcta gacctgatag aaagccagta
    90181 aaagatatga taaataagat aaataggaat agaaagtgga aagatatctt agaattgaca
    90241 agaagagctc catctgtaaa aaattctcaa ccgtggtatt tccataagga tgaacgaggt
    90301 cttcatttat ttgaaaagag acctaagaaa cactgtgaag atatgaataa ggttagctta
    90361 ggtgtagcct taagacattt tgatatagct tgtataaaaa ataaaataga tgtttcatat
    90421 gaaaaacttc ctataaggaa taaaatagga aaatcatatt ttataactgt agtcgagcat
    90481 gtgaaaccag aagaagaaac ccaagaagaa aatgtaactc tagaaaaaga agaatcgcaa
    90541 gatgaataaa attttggaag gggatattgg atatgtataa gtgtggaaaa tgtaatctta
    90601 gaggctgttc taatggaaat atggataaat taatgaagat atgtccaact agagaaattg
    90661 aactacaaca aaaagcaaag caactttatg aagaagaaga gaatagaaaa atagcttata
    90721 atgctggatt agttgaagca gaggggtatt gtcaatatac tagactaaaa gagattatag
    90781 agtttgctaa aaagtgtggt tataaaaaga ttggcatagc attttgtatt ggactaaaaa
    90841 gagaaatgca aacagtgcaa aaaatatttg aacatcatgg gtttgaagta ttttctgtta
    90901 tatgtaaaaa tggggcaatg cctaagagta caattggact agaagcatct caaacaatat
    90961 caaagtgttc agatgaggta atgtgcaatc caataggaca agctttattt ttaaatgaag
    91021 ctaaggttga ccttaatgta attcttggat tatgtgttgg tcacgatact ttagccatga
    91081 aatatatgga agctcctata acaactttag ttgtcaaaga tagagtaact gggcataatc
    91141 cagttgctgc aatatataat gcagaatcat attttgagaa aaaattgttt gataaagatg
    91201 aagaataatt caaagactta ttgacataaa aagcaattag tggtttaatt ataaaaaaga
    91261 taaaacttta aattatccta tagatacata aagttatata aataaagaaa aatattacag
    91321 ctaaattcct taaagtagtc cagagagact aaagggttat agataatgtt agtatataac
    91381 ctctagtaaa tcttctagag gtttttgatg agtataaaat aaaaatttaa atataataaa
    91441 gtcttttaaa ctagtccaga gagactggga aagatatctc atagctaatg aatagagtta
    91501 tgtatagata aaatccttat gcctcttttg gtgtgaggat ttttttatga ttatttaggc
    91561 tttattaaaa aggagatgta aaaatgataa atggtaaaga aaaattgata gttgcaattg
    91621 atactgacga atttgataaa gctaaagaac taatagacag attagaagat agtgtagaca
    91681 tatttaaggt agggctagag caatacgttg ccacaaaagg taaaacaata gattatctta
    91741 aagaaaaagg gaaaaaaata tttttagacc ttaaattcca tgatatacca aatactatga
    91801 aaagtgcagt gaaagctgca gtgagagata atgtttggtt aatgacaata catgtatcag
    91861 atatggaagg aatgagacaa tgtgcactaa ttgctaggga agaagcagaa agattaaata
    91921 tagaaaagcc attagtagtt ggagtaacag ttttaacttc attaagcaac caagatttac
    91981 aggacatagg atgtaatatg acaacagaag agttagctat aaagagagct aaactggcaa
    92041 aagaatcagg aatagatggg gttgtttgtt cagcgcaaga agtagataaa atagtagaag
    92101 catgtggaac tgattttata acagtttgcc caggaataag acctaaatca gcagaggttg
    92161 gagaccaaaa aagagttgta actccatcag atgcaataaa aaaaggtgct cattatttag
    92221 ttgttggaag acctataaca aaagcagaaa atccaagaga atcagctatt aatattgtaa
    92281 gagaaataga aaatgcttag ataaaatatt tgggaggtag cttacatgaa ggggaaatta
    92341 attttagaag atggaacagt atttgaagga aaagcatttg gatatctaaa ggaagctatt
    92401 ggagaagttg tatttaatac ttcaatggct gggtatggag aactattgac agatgcaact
    92461 tattatggac aaatagttac tatgacttat ccacttatag gaaactatgg aataaattta
    92521 gaagatgttg aatcaaataa ggtgcaagta aaaggactta ttgtaagaga aaaaagtgat
    92581 aacccaaata attttagatg tgaaatggat atagacacat atctaaagca aaataaggta
    92641 ataggacttg aaggaataga tacaagagca ttaactaaaa ttattagaaa caatggaact
    92701 aagagaggaa ttataacttt agaaaatgta tcattacaag atgttcagtc taaattagaa
    92761 gagcattgta acaaagattc agtaaaaaat gttacaagaa aagaaattga aaatataaaa
    92821 ggtactggag ctaaagttgt agttatagac tttggtgtta aaaatagtgt actagagtct
    92881 cttaaggctt gtaactgtga tataactata gtaccagcaa tgactacagt agaagaaatt
    92941 ttaaatataa atcctgactt aatcttatta tctaatggcc caggaaatcc agaggatata
    93001 aatgatatag ttgaaaatat aaaaaaatta ataggcaaaa agccattgac aggaataggt
    93061 ttaggacatc aaattttagc attggcatta ggaggaaaga cttcaaagct tgtatttgga
    93121 catagaggag gtaatcaccc agttaaatgt ttagaaactg gaaaggtatt tataacttct
    93181 caaaatcatg gatataatgt ttcagaaatg ccagaaaata cagaagtaac tcacataaat
    93241 ttaaatgaca atactataga aggaatgaga cataaggaat taccaatata tagtgttcaa
    93301 tacattccag aatacacaac aaaagaagat ttagattgta tatttaataa attcttagca
    93361 ttaatataga tttagtatta tttacagata gtaaaaacca tttagataag gagaaaaatt
    93421 tatgcctaaa ttagatagta taaagaaaac tttagtatta gggtcaggac caataataat
    93481 aggtcaagct gcagagtttg actattcagg aacacaagct tgccagtctt tgaaagagga
    93541 aggaattgaa gttgtattaa taaatagtaa tccagccact ataatgactg ataaagaagt
    93601 ggcagataaa atatatatag aaccattaac aatagaattt atagaaaaaa taatagaaaa
    93661 agaaagacca gacagtttac ttgcaggtat gggtggacaa acagggctaa acctagcagt
    93721 tgaactttat gaaaaaggca tactagataa atatggagta aagataatag gtacttcagt
    93781 agaatctatc aaaaaaggtg aagatagaga tatatttaga gaagtaatga aagaaataaa
    93841 tcagcctgta atagttagtg atatagttac agatttacaa gcaggtcttg attatgcact
    93901 tacaattggt tatccagtag ttgtaagacc agcatacaca ctaggtggaa ctggtggggg
    93961 tatagctgat aatgaggaag aattaagaga aatactttca catggtctac aattaagtcc
    94021 tgttggacaa gtattaattg aaaagagtat aaaaggttgg aaagaaatag aatatgaggt
    94081 aataagagat tcaaagggaa attgtatagt tgtatgtaac atggaaaata tagacccagt
    94141 cggagttcat acaggagaca gtatagttgt tgctccaact caaactttaa gtaacaaaga
    94201 atgtgcaatg cttaaaaaag catctttaga tatattaaat gcagtagaag ttcaaggtgg
    94261 ttgtaacgtt caatttgcac ttaatccaca tagttttgaa tatgcagtta tagagataaa
    94321 tccaagagtt agtaggtcat cagctttagc atcaaaagct acaggatatc caatagctaa
    94381 agtttcgtca aaaatagctt taggttatac tttagatgag atagaaaatg cagtaactaa
    94441 aaaaacttat gcttgttttg aaccaactat agattatgtg gtggcaaaaa taccaaaatg
    94501 gccttttgat aaatttaaaa aagcaaatag aaaattagga actaagatga tggcaactgg
    94561 tgaaattatg agtataggaa gtaactttga ggctgctatt cttaaaggga taagatcact
    94621 tgaaacagga aaatattcat tagttcacac accatctgag gagagaagca ttgaggaatt
    94681 aaagaaaaga gttgtagtac ctgatgatga gagactattt gatttagctg aaatgataag
    94741 aagaggctat aaagtagaaa tgatagaaca aattacaggt atagataaat ggtttataaa
    94801 taaatttaaa tggatagtag agcaagaaga aaaattaaaa gttatgaaaa ttgaagattt
    94861 aactaaagac tatcttcttg aattaaagaa aaagggattc tctgataaag gtatatctga
    94921 cctaatgaag ataagtccag aaaaattata tgaattgaga agtctataca atataaaacc
    94981 agcatataaa atggttgata cttgtgcagg tgagatagat gctatatctc cttactatta
    95041 ttcaacttat gagcaatatg atgaggtagt tgttagtgat aagaaaaagg tgatagtatt
    95101 aggttctggt ccaataagaa taggtcaagg tatagaattt gactattgtt cagttcactg
    95161 tgtaaaatct ttaagaaaaa tggacataga aactataatc ataaacaata accctgaaac
    95221 tgtaagtaca gactttgata catcagataa gctgtatttt gaaccattaa cagaagaaga
    95281 agttttaagt ataatagaaa aagaaaagcc agaaggtgta atactacagt ttggtggaca
    95341 aacagctata aaattggcta aatttttaca tgaaaaaaat atacctatat tgggaactga
    95401 ttttgatgat atagatgcag cagaagatag agaaaaattt gatgatttac tagagagact
    95461 agatataaat agaccaaaag gaaagggtgt atggtcactt aacgaaggta ttgaagttgc
    95521 taatgagtta ggttatccag tattagttag accatcttat gtacttggtg gtcaaggtat
    95581 ggaaataact tataacgaag aaaaattatc tcaataccta caagatgcat ttgatagaga
    95641 ccataaaaat ccagtactta tagataaata tctaactggt agagaaatag aagtagatgc
    95701 tatatgtgat aaggaagata tattgatacc tggtataatg ga
//
LOCUS       DAYAKB010000005        91755 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.005, whole genome shotgun sequence.
ACCESSION   DAYAKB010000005 DAYAKB010000000
VERSION     DAYAKB010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 91755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91755
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.005"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1071
                     /locus_tag="ACGI3L_000439"
     CDS             <1..1071
                     /locus_tag="ACGI3L_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFG9196170.1"
                     /translation="YIVNLSKEYYFEHKQWIKKNDIQKLIKGKYNLHSQTIQAISDKF
                     DANRKTISELRKKGNTKAKYPYKTKKFYIIPFKASAINRNAKGNLKLSMSKGRYLELD
                     FNVENIKTAEIVWRNGYYLYYTFDNELNGVVAKGTNTVGVDLGEIHSIASVTNKGVGL
                     ILSNREGRSIKQFRNKMYAYISKRLSKCKKGSRQSKKLWRLKNKIRSKTDNQLMNLYH
                     QTTRKFIDFCVEQKVCEIVLGDIKGVEKDTKKKKRLNRVNRQKISQMEYGRIKDYIKY
                     KAKEQGIEVKLVKENYTSQTCPKCSKKHKPTGRTYSCTCGYETHRDIVGAWNILNKKH
                     KYGLVDFRINHKQPINLKVSTV"
     gene            complement(1455..1967)
                     /locus_tag="ACGI3L_000440"
     CDS             complement(1455..1967)
                     /locus_tag="ACGI3L_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9196171.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            2417..2893
                     /gene="purE"
                     /locus_tag="ACGI3L_000441"
     CDS             2417..2893
                     /gene="purE"
                     /locus_tag="ACGI3L_000441"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFG9196172.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDNNLRG"
     gene            2899..3597
                     /gene="purC"
                     /locus_tag="ACGI3L_000442"
     CDS             2899..3597
                     /gene="purC"
                     /locus_tag="ACGI3L_000442"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFG9196173.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            3609..4976
                     /gene="purF"
                     /locus_tag="ACGI3L_000443"
     CDS             3609..4976
                     /gene="purF"
                     /locus_tag="ACGI3L_000443"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFG9196174.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            4970..6046
                     /gene="purM"
                     /locus_tag="ACGI3L_000444"
     CDS             4970..6046
                     /gene="purM"
                     /locus_tag="ACGI3L_000444"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFG9196175.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMERYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAVAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            6040..6633
                     /gene="purN"
                     /locus_tag="ACGI3L_000445"
     CDS             6040..6633
                     /gene="purN"
                     /locus_tag="ACGI3L_000445"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFG9196176.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            6626..8158
                     /gene="purH"
                     /locus_tag="ACGI3L_000446"
     CDS             6626..8158
                     /gene="purH"
                     /locus_tag="ACGI3L_000446"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFG9196177.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            8169..9419
                     /gene="purD"
                     /locus_tag="ACGI3L_000447"
     CDS             8169..9419
                     /gene="purD"
                     /locus_tag="ACGI3L_000447"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFG9196178.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            9444..13250
                     /locus_tag="ACGI3L_000448"
     CDS             9444..13250
                     /locus_tag="ACGI3L_000448"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFG9196179.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKETSIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            13456..14328
                     /gene="rfbD"
                     /locus_tag="ACGI3L_000449"
     CDS             13456..14328
                     /gene="rfbD"
                     /locus_tag="ACGI3L_000449"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFG9196180.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            14437..15306
                     /gene="rfbA"
                     /locus_tag="ACGI3L_000450"
     CDS             14437..15306
                     /gene="rfbA"
                     /locus_tag="ACGI3L_000450"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFG9196181.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            15355..15912
                     /gene="rfbC"
                     /locus_tag="ACGI3L_000451"
     CDS             15355..15912
                     /gene="rfbC"
                     /locus_tag="ACGI3L_000451"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFG9196182.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            15950..16933
                     /gene="rfbB"
                     /locus_tag="ACGI3L_000452"
     CDS             15950..16933
                     /gene="rfbB"
                     /locus_tag="ACGI3L_000452"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFG9196183.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            16963..17631
                     /locus_tag="ACGI3L_000453"
     CDS             16963..17631
                     /locus_tag="ACGI3L_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HFG9196184.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVNQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            17640..18068
                     /locus_tag="ACGI3L_000454"
     CDS             17640..18068
                     /locus_tag="ACGI3L_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HFG9196185.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            18092..18406
                     /locus_tag="ACGI3L_000455"
     CDS             18092..18406
                     /locus_tag="ACGI3L_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFG9196186.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVKVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            18557..18832
                     /gene="flgM"
                     /locus_tag="ACGI3L_000456"
     CDS             18557..18832
                     /gene="flgM"
                     /locus_tag="ACGI3L_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HFG9196187.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            18837..19253
                     /locus_tag="ACGI3L_000457"
     CDS             18837..19253
                     /locus_tag="ACGI3L_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HFG9196188.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGNDISMSEVVENSNDGYLKEIYTDLKRILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            19271..20581
                     /gene="flgK"
                     /locus_tag="ACGI3L_000458"
     CDS             19271..20581
                     /gene="flgK"
                     /locus_tag="ACGI3L_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HFG9196189.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            20600..21532
                     /gene="flgL"
                     /locus_tag="ACGI3L_000459"
     CDS             20600..21532
                     /gene="flgL"
                     /locus_tag="ACGI3L_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HFG9196190.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            21548..21940
                     /gene="fliW"
                     /locus_tag="ACGI3L_000460"
     CDS             21548..21940
                     /gene="fliW"
                     /locus_tag="ACGI3L_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006417 - regulation of translation
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HFG9196191.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            21934..22146
                     /gene="csrA"
                     /locus_tag="ACGI3L_000461"
     CDS             21934..22146
                     /gene="csrA"
                     /locus_tag="ACGI3L_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HFG9196192.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            22168..22563
                     /gene="fliS"
                     /locus_tag="ACGI3L_000462"
     CDS             22168..22563
                     /gene="fliS"
                     /locus_tag="ACGI3L_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HFG9196193.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            22563..22919
                     /gene="fliS"
                     /locus_tag="ACGI3L_000463"
     CDS             22563..22919
                     /gene="fliS"
                     /locus_tag="ACGI3L_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HFG9196194.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            22940..24463
                     /gene="fliD"
                     /locus_tag="ACGI3L_000464"
     CDS             22940..24463
                     /gene="fliD"
                     /locus_tag="ACGI3L_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HFG9196195.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            24466..24801
                     /locus_tag="ACGI3L_000465"
     CDS             24466..24801
                     /locus_tag="ACGI3L_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HFG9196196.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            24903..25775
                     /locus_tag="ACGI3L_000466"
     CDS             24903..25775
                     /locus_tag="ACGI3L_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HFG9196197.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            25868..28009
                     /locus_tag="ACGI3L_000467"
     CDS             25868..28009
                     /locus_tag="ACGI3L_000467"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196198.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            28033..29910
                     /locus_tag="ACGI3L_000468"
     CDS             28033..29910
                     /locus_tag="ACGI3L_000468"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196199.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            29903..32017
                     /locus_tag="ACGI3L_000469"
     CDS             29903..32017
                     /locus_tag="ACGI3L_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196200.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDRIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            32026..33021
                     /locus_tag="ACGI3L_000470"
     CDS             32026..33021
                     /locus_tag="ACGI3L_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0044038 - cell wall macromolecule
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HFG9196201.1"
                     /translation="MNNIHINKFEKSCERNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            33113..34345
                     /locus_tag="ACGI3L_000471"
     CDS             33113..34345
                     /locus_tag="ACGI3L_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFG9196202.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            34365..35309
                     /locus_tag="ACGI3L_000472"
     CDS             34365..35309
                     /locus_tag="ACGI3L_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HFG9196203.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ELFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            35403..35810
                     /locus_tag="ACGI3L_000473"
     CDS             35403..35810
                     /locus_tag="ACGI3L_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HFG9196204.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            35888..36988
                     /locus_tag="ACGI3L_000474"
     CDS             35888..36988
                     /locus_tag="ACGI3L_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HFG9196205.1"
                     /translation="MNLLLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHF
                     EEEFANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGAT
                     PVFVEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDC
                     AQSHGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGS
                     EKRYYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKI
                     ENNCTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNI
                     AENYSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      37297..37387
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            37796..38113
                     /gene="flgB"
                     /locus_tag="ACGI3L_000475"
     CDS             37796..38113
                     /gene="flgB"
                     /locus_tag="ACGI3L_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HFG9196206.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            38121..38525
                     /gene="flgC"
                     /locus_tag="ACGI3L_000476"
     CDS             38121..38525
                     /gene="flgC"
                     /locus_tag="ACGI3L_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030694 - bacterial-type flagellum basal
                     body, rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HFG9196207.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            38535..38852
                     /gene="fliE"
                     /locus_tag="ACGI3L_000477"
     CDS             38535..38852
                     /gene="fliE"
                     /locus_tag="ACGI3L_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HFG9196208.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            38877..40427
                     /gene="fliF"
                     /locus_tag="ACGI3L_000478"
     CDS             38877..40427
                     /gene="fliF"
                     /locus_tag="ACGI3L_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body MS-ring/collar protein
                     FliF"
                     /protein_id="HFG9196209.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            40440..41510
                     /gene="fliG"
                     /locus_tag="ACGI3L_000479"
     CDS             40440..41510
                     /gene="fliG"
                     /locus_tag="ACGI3L_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HFG9196210.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            41494..42234
                     /locus_tag="ACGI3L_000480"
     CDS             41494..42234
                     /locus_tag="ACGI3L_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliH/SctL family protein"
                     /protein_id="HFG9196211.1"
                     /translation="MTLLNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFR
                     DEVIKEAIESAEIRKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYT
                     QKAKDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESM
                     SDLLKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGN
                     AIIQKENGRIIVGIDCAMEKLKEELLGE"
     gene            42238..43557
                     /gene="fliI"
                     /locus_tag="ACGI3L_000481"
     CDS             42238..43557
                     /gene="fliI"
                     /locus_tag="ACGI3L_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HFG9196212.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            43589..44035
                     /gene="fliJ"
                     /locus_tag="ACGI3L_000482"
     CDS             43589..44035
                     /gene="fliJ"
                     /locus_tag="ACGI3L_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HFG9196213.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDNVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            44063..45268
                     /locus_tag="ACGI3L_000483"
     CDS             44063..45268
                     /locus_tag="ACGI3L_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HFG9196214.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNNKFEDNLYKTTDHKNV
                     KDRRETSKQNVSSDRPGNSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNLELNGANTNNPNDIE
                     NLDIMKLRELLENNASEDIQVISKTTENDTKSIDLYSFDSNRMDTLNSNKQKDDSSDI
                     LEKLAGLNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSNQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            45286..45894
                     /locus_tag="ACGI3L_000484"
     CDS             45286..45894
                     /locus_tag="ACGI3L_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook capping FlgD N-terminal
                     domain-containing protein"
                     /protein_id="HFG9196215.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEDEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVDVKYEKLLKIGEVEANSGEENDSSEQESPEEV"
     gene            45921..46904
                     /locus_tag="ACGI3L_000485"
     CDS             45921..46904
                     /locus_tag="ACGI3L_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HFG9196216.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            46917..47120
                     /locus_tag="ACGI3L_000486"
     CDS             46917..47120
                     /locus_tag="ACGI3L_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HFG9196217.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            47120..47938
                     /locus_tag="ACGI3L_000487"
     CDS             47120..47938
                     /locus_tag="ACGI3L_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HFG9196218.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEINEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            47928..48623
                     /locus_tag="ACGI3L_000488"
     CDS             47928..48623
                     /locus_tag="ACGI3L_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HFG9196219.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKEDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPKLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            48635..49078
                     /gene="fliL"
                     /locus_tag="ACGI3L_000489"
     CDS             48635..49078
                     /gene="fliL"
                     /locus_tag="ACGI3L_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HFG9196220.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            49093..49467
                     /locus_tag="ACGI3L_000490"
     CDS             49093..49467
                     /locus_tag="ACGI3L_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HFG9196221.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            49468..50133
                     /gene="fliP"
                     /locus_tag="ACGI3L_000491"
     CDS             49468..50133
                     /gene="fliP"
                     /locus_tag="ACGI3L_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HFG9196222.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            50146..50415
                     /gene="fliQ"
                     /locus_tag="ACGI3L_000492"
     CDS             50146..50415
                     /gene="fliQ"
                     /locus_tag="ACGI3L_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HFG9196223.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            50427..52241
                     /locus_tag="ACGI3L_000493"
     CDS             50427..52241
                     /locus_tag="ACGI3L_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HFG9196224.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLINNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKSFIDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPIAMTLLAFTLLVPTLFSYVVNTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            52250..54325
                     /gene="flhA"
                     /locus_tag="ACGI3L_000494"
     CDS             52250..54325
                     /gene="flhA"
                     /locus_tag="ACGI3L_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HFG9196225.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            54303..55316
                     /gene="flhF"
                     /locus_tag="ACGI3L_000495"
     CDS             54303..55316
                     /gene="flhF"
                     /locus_tag="ACGI3L_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HFG9196226.1"
                     /translation="MTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFSK
                     KDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLNQ
                     EIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTIA
                     KLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMK
                     DCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNV
                     NFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLGV
                     ESI"
     gene            55313..56191
                     /locus_tag="ACGI3L_000496"
     CDS             55313..56191
                     /locus_tag="ACGI3L_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HFG9196227.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVGVCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            56205..56906
                     /locus_tag="ACGI3L_000497"
     CDS             56205..56906
                     /locus_tag="ACGI3L_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9196228.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDTEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            56922..57344
                     /locus_tag="ACGI3L_000498"
     CDS             56922..57344
                     /locus_tag="ACGI3L_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HFG9196229.1"
                     /translation="MIQIILIVVSILIIVTIVINLQKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            57329..57514
                     /locus_tag="ACGI3L_000499"
     CDS             57329..57514
                     /locus_tag="ACGI3L_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HFG9196230.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            57555..58328
                     /locus_tag="ACGI3L_000500"
     CDS             57555..58328
                     /locus_tag="ACGI3L_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HFG9196231.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            58349..59110
                     /locus_tag="ACGI3L_000501"
     CDS             58349..59110
                     /locus_tag="ACGI3L_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HFG9196232.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGKDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            59133..60014
                     /locus_tag="ACGI3L_000502"
     CDS             59133..60014
                     /locus_tag="ACGI3L_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFG9196233.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNECIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            60017..60391
                     /locus_tag="ACGI3L_000503"
     CDS             60017..60391
                     /locus_tag="ACGI3L_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFG9196234.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            60423..61826
                     /locus_tag="ACGI3L_000504"
     CDS             60423..61826
                     /locus_tag="ACGI3L_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9196235.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYNSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            61942..63879
                     /gene="htpG"
                     /locus_tag="ACGI3L_000505"
     CDS             61942..63879
                     /gene="htpG"
                     /locus_tag="ACGI3L_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HFG9196236.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            64267..65397
                     /locus_tag="ACGI3L_000506"
     CDS             64267..65397
                     /locus_tag="ACGI3L_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFG9196237.1"
                     /translation="MNFNYNLPVNILFGSGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIKKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            65624..66646
                     /gene="splB"
                     /locus_tag="ACGI3L_000507"
     CDS             65624..66646
                     /gene="splB"
                     /locus_tag="ACGI3L_000507"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006290 - pyrimidine dimer repair [Evidence
                     IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HFG9196238.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            66828..67739
                     /locus_tag="ACGI3L_000508"
     CDS             66828..67739
                     /locus_tag="ACGI3L_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9196239.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            67754..68170
                     /locus_tag="ACGI3L_000509"
     CDS             67754..68170
                     /locus_tag="ACGI3L_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HFG9196240.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(68270..68662)
                     /locus_tag="ACGI3L_000510"
     CDS             complement(68270..68662)
                     /locus_tag="ACGI3L_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9196241.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            68803..69198
                     /locus_tag="ACGI3L_000511"
     CDS             68803..69198
                     /locus_tag="ACGI3L_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFG9196242.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            69601..69807
                     /locus_tag="ACGI3L_000512"
     CDS             69601..69807
                     /locus_tag="ACGI3L_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196243.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(70119..70862)
                     /locus_tag="ACGI3L_000513"
     CDS             complement(70119..70862)
                     /locus_tag="ACGI3L_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HFG9196244.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            71028..73595
                     /locus_tag="ACGI3L_000514"
     CDS             71028..73595
                     /locus_tag="ACGI3L_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9196245.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            73825..74229
                     /locus_tag="ACGI3L_000515"
     CDS             73825..74229
                     /locus_tag="ACGI3L_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9196246.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            74253..74750
                     /locus_tag="ACGI3L_000516"
     CDS             74253..74750
                     /locus_tag="ACGI3L_000516"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196247.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            74753..75154
                     /locus_tag="ACGI3L_000517"
     CDS             74753..75154
                     /locus_tag="ACGI3L_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9196248.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            75172..75660
                     /locus_tag="ACGI3L_000518"
     CDS             75172..75660
                     /locus_tag="ACGI3L_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFG9196249.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            75687..76442
                     /locus_tag="ACGI3L_000519"
     CDS             75687..76442
                     /locus_tag="ACGI3L_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9196250.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            76442..77305
                     /locus_tag="ACGI3L_000520"
     CDS             76442..77305
                     /locus_tag="ACGI3L_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9196251.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            77352..77831
                     /locus_tag="ACGI3L_000521"
     CDS             77352..77831
                     /locus_tag="ACGI3L_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HFG9196252.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            77896..79203
                     /locus_tag="ACGI3L_000522"
     CDS             77896..79203
                     /locus_tag="ACGI3L_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9196253.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            79531..79653
                     /locus_tag="ACGI3L_000523"
     CDS             79531..79653
                     /locus_tag="ACGI3L_000523"
                     /inference="COORDINATES: protein motif:HMM:NF021468.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HFG9196254.1"
                     /translation="MLSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDENGE"
     gene            80163..81257
                     /locus_tag="ACGI3L_000524"
     CDS             80163..81257
                     /locus_tag="ACGI3L_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196255.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            81262..81462
                     /locus_tag="ACGI3L_000525"
     CDS             81262..81462
                     /locus_tag="ACGI3L_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLD nuclease N-terminal domain-containing
                     protein"
                     /protein_id="HFG9196256.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            81459..82379
                     /locus_tag="ACGI3L_000526"
     CDS             81459..82379
                     /locus_tag="ACGI3L_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9196257.1"
                     /translation="MMNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKT
                     TTMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCG
                     EITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDE
                     PTSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLS
                     EIKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTV
                     ISTLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            82376..83134
                     /locus_tag="ACGI3L_000527"
     CDS             82376..83134
                     /locus_tag="ACGI3L_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFG9196258.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTIYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            83382..84455
                     /locus_tag="ACGI3L_000528"
     CDS             83382..84455
                     /locus_tag="ACGI3L_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HFG9196259.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            84525..84788
                     /locus_tag="ACGI3L_000529"
     CDS             84525..84788
                     /locus_tag="ACGI3L_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196260.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            84994..85971
                     /gene="bioB"
                     /locus_tag="ACGI3L_000530"
     CDS             84994..85971
                     /gene="bioB"
                     /locus_tag="ACGI3L_000530"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HFG9196261.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            86191..87213
                     /locus_tag="ACGI3L_000531"
     CDS             86191..87213
                     /locus_tag="ACGI3L_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9196262.1"
                     /translation="MNFLSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKI
                     MKEKNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNT
                     DEDAKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETL
                     KGIVKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYN
                     PAYVFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVV
                     GFDDIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRD
                     STKESE"
     gene            87255..88145
                     /gene="rbsK"
                     /locus_tag="ACGI3L_000532"
     CDS             87255..88145
                     /gene="rbsK"
                     /locus_tag="ACGI3L_000532"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFG9196263.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            88193..89155
                     /locus_tag="ACGI3L_000533"
     CDS             88193..89155
                     /locus_tag="ACGI3L_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFG9196264.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            89209..90720
                     /locus_tag="ACGI3L_000534"
     CDS             89209..90720
                     /locus_tag="ACGI3L_000534"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HFG9196265.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            90704..91702
                     /locus_tag="ACGI3L_000535"
     CDS             90704..91702
                     /locus_tag="ACGI3L_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9196266.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
BASE COUNT        37364 a         9443 c        16804 g        28144 t
ORIGIN      
        1 tacatagtta acttatctaa agaatactat tttgaacata aacaatggat taaaaagaat
       61 gatatacaaa agttaatcaa aggtaagtac aatcttcata gtcaaactat tcaagctata
      121 tcagataaat ttgatgcaaa tagaaagact atatcagaat taagaaaaaa aggtaatact
      181 aaagcaaaat atccatacaa gactaagaaa ttttatataa taccttttaa agctagtgct
      241 attaatagaa atgctaaagg caacttaaaa ttatcaatgt caaaaggcag gtatttagaa
      301 ttagatttta atgttgagaa tataaaaact gctgaaatag tatggcgaaa tggatattat
      361 ttatactaca cttttgacaa tgaattaaat ggagttgtag ccaaaggcac taataccgta
      421 ggtgtagact taggggaaat acattcgata gctagtgtaa caaataaagg tgtagggctt
      481 attctatcta atagagaagg cagaagtatt aaacaattta gaaataagat gtatgcttat
      541 atatctaaaa gattaagtaa atgtaaaaaa ggtagtagac aatcaaagaa gttatggaga
      601 ttaaaaaata agataagaag taaaacagat aatcagttaa tgaatttata tcatcaaaca
      661 actagaaagt ttatagactt ttgtgtagag cagaaggtat gtgaaatagt tcttggggat
      721 ataaaagggg ttgaaaaaga tactaagaaa aagaaaagat taaacagagt taatagacag
      781 aaaatatctc aaatggagta tggtcgaata aaggactata taaaatataa agcaaaagag
      841 caaggtattg aagttaagtt agttaaagaa aactacactt ctcaaacttg cccaaagtgt
      901 tctaaaaaac acaaaccaac tggtagaact tatagttgta cttgtggtta tgaaactcat
      961 agagatatag ttggtgcttg gaatatttta aataaaaagc ataaatatgg tttagtagat
     1021 tttagaataa atcataagca accaataaat ttaaaagtat ctaccgtttg agccatgtgt
     1081 gggcgaataa ctttaaggta gtagtggcga agacaccgtc cgaagtagct tggctttgta
     1141 accacctctg ttgtactgtt taagtataaa taagtgtgtt agccaccaag aatccccttg
     1201 ctttagctat ggggagtgtg tcaataaaat actttaatga aaaatagcta actttaattg
     1261 taggatattc ttaatatatt tgaaataaat aaaaatattg aaggatataa tattcaactg
     1321 gtatataaat aataaatgat agttaaattt taccttagag gctaattagg tgtttagtca
     1381 aagctaatgc ctttagaata caaatgtatt ctaaaggcat ttttactatg tattttcatt
     1441 tatattacta aacattatct atttttatat acatttctat gtattttatt ttcatcaaat
     1501 cggtctataa actcattttt ttcttcacta tatccaatag atataagtgc ataaggaact
     1561 aattttaatg gtaagtctaa agtttgtcta actttattta ccactttatt tttaggaaat
     1621 actcctgccc aacaagcagc tagaccttga ttagtaactt ctaataataa attttgtgtg
     1681 caagcaccta aatcttgtat ccatttacca ggttttaaga atttatctct atttccaagc
     1741 actactatac ataatggtgc aaattctata tgctttgctc tatgctgtga ctttgagagc
     1801 tgtttcagca gttccttatc atctactata ataaattccc aaggttgagc attttttgat
     1861 gaaggtgctt gcatagctga ttttagtatt tcagttattt tatcttcttc tatattttta
     1921 tctatatatg ttcttattga acgtctattt tttataactt ctaacataca gattctcctt
     1981 taaataaaat tatttctatt tatataatat cattacttta aattttagct attacttata
     2041 taaagaataa actttgtgtt ggttttatct aagtaaaagt aacattcaga actaaaaaac
     2101 aagactataa atccaaagta ttaattaaaa aagaagtaat aaaaaataat atacaagatt
     2161 taaaaaagag tattgggctt aaaatttaat tagaaaacca attttgagat aatctgtttt
     2221 ttattttaac aaaaaaacat aaataaagtt cgatacgtag cgaatgaaaa aattacaaga
     2281 aatatttttt ttaaaaaatt tcaaaaaaga gttgataata tatgtatatt aatataaaat
     2341 ttaaggtgta taattcgtat aataatacga atgatttgta gtgtaaaata acttataaac
     2401 ggagagggga agtctaatga aagtagcagt agttatgggt tcaaaatcag attatccaaa
     2461 attagaagaa gggataaaac tgcttgaaaa atatggaata gaagttgtag caagagcatt
     2521 atcagctcat agaacaccag aacaactttc aatattccta aaagaaatag aagatgatac
     2581 tgatgtaata atagcagcag caggaaaagc agcacactta ccaggtgtaa tagcttcaca
     2641 aacattaatt cctgtaatag gattacctat taaatcatca actatggatg gactagactc
     2701 acttttatca atagttcaaa tgccaaaagg aatcccagtt gcaacagtta caatagactt
     2761 aggtttaaac gcagctttat tggcattaca aataatgact ttaaaatacc caaaattaaa
     2821 agaggatttg aaatcatata gagaagagat ggcacaaaag gtgttagaag acgacaataa
     2881 tttaaggggg tagcagaaat gttattatat gaaggaaaag caaaacaagt atattctaca
     2941 gataatgaaa atgaatatgt tgtttattat aaagatgatg caacagcatt taatggagaa
     3001 aaaaaagcag aaatatcttc aaaaggtata ctaaataata agatatcaac aataatcttt
     3061 gaaatgttaa aagaaaataa tataaatact cactttataa aaagtttatc agatagagaa
     3121 atgttagtta aaaaagtaga gattttacca ttagaagtaa tagtaagaaa tattgctgct
     3181 ggttctatct gtaaaagagt tggtcttgaa gaaggtgtag ttttcgatga gccaattttt
     3241 gaaataagct acaaaaatga tgcttatggt gacccaatgc taaatgatga ttatgcagtg
     3301 gcaatgaagt tagcaactag agaagagtta aaattcttaa gagaagaaac tttaaaaata
     3361 aatgagttac taaaagcatt tttcttaaaa ttaaacctaa agttagttga ctttaaaata
     3421 gaatttggta aggattctga aggaaatata atattggcag atgaagtatc accagacact
     3481 tgtagacttt gggatgtaaa tacaaatgaa aagttagata aggacagatt tagaaaagac
     3541 cttggagacc ttgtagaagg ttatacggaa gtactttcaa gaatgaataa taaataggag
     3601 gcaaatgtat gtgtggagtt ttagggattt actctaataa agatgtaact aaagaactat
     3661 attattcttt atattctatg caacacaggg ggcaagaaag ctgtggttta gctcttttag
     3721 atgatggaga aattaagtac aaaaaagata tgggattagt tggagatgtt tttaaggaaa
     3781 atgaattatc taagttaaaa ggaaatatag ggattggaca tgttagatat tcaacagctg
     3841 gaggaagtca tgtttctaat tgtcaacctt tagttggaag ttgtagaaaa agacaattag
     3901 ccatagctca taatggaaat ctagttaatg caaattattt aaaagatatg ctagaagaag
     3961 atggatatat gttccaaact aattcagata cagaagtgat tttatatata cttgctagat
     4021 attacaaagg ggatatagta gaaagtttaa aagtgacaat ggattatata aaaggtgcat
     4081 atgctcttgt aataatgagt caagaagaat tggttgcagt tagagaccca catggattca
     4141 gacctcttgt acttggtaaa aagggtgatg aatatatatt tgcatcagaa aattgtgcaa
     4201 tagatatact tggcggagaa gttataagag atgtagagcc aggagagata atagtagtca
     4261 aagatggaga actaaaatca tatttttatt cagaaaatta taaaccagtt aagaaaagtt
     4321 gtatatttga acacatatac tttgcaagaa atgatgcaac tatagacaat gtaaatgcat
     4381 atgaatttag aattaaatgt ggtgagagat tagctcagaa tgaaactgta aaggcagata
     4441 tggtagttcc agttccagat tcaggttggc caggagctat tggttatgca aatgctagtg
     4501 gattaaaaat aagtgaaggc ttagttaaaa atagatatgt aggaagaaca tttataaaac
     4561 ctacacaaga agaaagagaa atagcagtaa aaataaaatt aaatcctctt tcaacaataa
     4621 taaaaggaaa atctataatt ttagtagacg actcaattgt aagaggaact acatctaaac
     4681 aattagtaaa atctttaaga gaagcaggtg caaaagaaat tcatcttaga ataacttctc
     4741 ctccagtagc ttactcttgt tactatggaa tagatactcc aaatcgctct aaattaattg
     4801 catcaagtaa caacgtagaa gaaatgagag aatatattgg atgtgatagt ttaaaattcc
     4861 tagatataga aggaatgtta gatgcaacag aacataagtc tactttctgt aaagcttgtt
     4921 ttgatggaga atacccagtt aagaaaattg ataaggagga actactttca tgttaacata
     4981 taaagaatca ggtgtagata tagatgaagg aaatagagca gtagacctta taaaaggtaa
     5041 aataaaagga acttatgatg gaaatgtagt tggagattta ggtaacttca gtggattata
     5101 cagtttaaaa gattttgtag gtatgaaaga accagttttg cttgcatcta cagatggtgt
     5161 tgggactaag ttaaaaatag ctcagatgat ggacaagcat gatactgttg gaatagattt
     5221 agttgcaatg tgcgtgaatg atttaatttg tcaaggagca aaaccattat tcttccttga
     5281 ctatatagct cttgggaaat tagtgcctga gcatatagaa aaaatagttg gtggaattgc
     5341 agatggttgc aaaatgtctg gttgtgcact aattggtgga gaaactgctg aaatgcctgg
     5401 aatgtatgga gaagatgact atgatttagc aggattttct gtgggaatag cagacaaaga
     5461 aaagattgtt tctggaaaca atgttaaatc aggagatgta ttggttggta tatcttcaag
     5521 tggagtacac agcaatggat tttcttttat aagaaagata tttttagaaa cttacaatta
     5581 taaaatggaa cgatatgttg aagaactagg aatgacagtt ggagaagcac ttttaacacc
     5641 aactaaaata tatgttaaat tagctttaga tgtattagct aaacatgaca taaaagctgt
     5701 agctcacata actggtggag ggcttataga aaatataaca agagttatac ctaaaggatt
     5761 aggactagat atcaataaaa aatcttggga gaagcctcct atatttaaaa tgatagaagg
     5821 ttttaatgct gttgatgaga gagaacttca taagagtttt aacatgggta ttgggctagt
     5881 tttaatagta gataaagaaa atgctgatga tgttgtaaac tttataaata atagagaaaa
     5941 tgacaatgct gattatgtag ataaaaaata tagtgaatta ttagaagata aagcttatat
     6001 aattggtgaa gtagtagata gtcatgaagg tgtagaatta tgctaaatat aggagtttta
     6061 atatctggtg ggggaacaaa tttacaagca gttatagatg gtactgagtc tggagaaata
     6121 aaaggtcagg ttaaagtagt tatctcaagt aagcaaggtg cttatgggct agagagagct
     6181 aaaaatcata acataaaagc aatttgtgaa actgatgaag acaagataat agaaattctt
     6241 aaggaaaata aaatagattt agtagttttg gctggttatt taaaaataat cagcccaaag
     6301 ctggttaatg agtttagaaa caaaatgata aacatacatc catcattaat tccttcattt
     6361 tgtggagctg gattctatgg agaaaaagtt catcaaggtg ttatagatta cggagctaaa
     6421 gtaactggtg ctacagttca ttttgttgat gaaggtgctg atactggacc aatcataatg
     6481 caagatgtag ttaaggtaaa tcaagatgat gatgcaaaga cacttgcaaa aagagtgtta
     6541 gaagttgaac ataggatttt aaaagaaagt ataagtcttt tttgtgaaaa taaattaaaa
     6601 cttcaaggta ggagagtgtt tataaatgag taagagagct ttaataagtg taactgacaa
     6661 gactggtgta gtggaatttg ctaaagagtt aaataaatta gattatgaaa ttatatctac
     6721 aggaaataca tttaaaacat taaaagaaaa tggtgttaat gtaatgcaag ttgaagatgt
     6781 tacaaatttt ccagaaatat tagatggaag agtaaaaaca ttaaatccat atatacatgg
     6841 tggtatactt tataaaagag ataaagaatc tcatgtagaa actgtaaatg aacataaaat
     6901 acattcaata gatttagtag ctgtaaatct atatgatttt gaaggaactt taaaagctgg
     6961 aaaaagtcat gatgaaataa ttgaaaatat agatattggt ggaccatcta tgatacgttc
     7021 tgctgccaaa aactataagg atgtaatagt agtagtagat ataaaagatt atgattctat
     7081 aatagaaaaa ttaaaaacag atacaatgac attagaagac agaaaaaaat tatcatataa
     7141 agctttctca actacaggaa gatatgatgc gttaatatct agttattttg ctggagaagt
     7201 tggagatacg tatcctgaca tattaaattt aactttccaa aaagaacaaa ctttaagata
     7261 tggagaaaat ccacatcaaa atggtttctt atattcacag tcaaatgcaa aaaatccaat
     7321 cttaaattat gagcaattag gcggtaaaga actttctttt aacaacttaa atgatttaca
     7381 tggatgttta gaagtaatga gagaatttaa agatagtgaa gaagtagttt cagtagctat
     7441 aaaacatgct aattcatgtg gggtaggttt aggaaaagat gcttttgaag catatacaaa
     7501 atgttatgaa gcggataagg tttcaatatt tggaggaata gtaggaataa cttctactat
     7561 agataaagct acagcagaga aattaaatga aatattctta gaaatagtag tagcatatga
     7621 ttttgaacca gaagctttag agatacttaa acaaaagaaa aatctaagaa tattaaaatt
     7681 agctaaaata gaaaatagtt tacaaccata tgaaatgaaa tatttagatg gaaaattatt
     7741 gatacaagat agaaacaata tattagcaga aaaaagtgaa aatgtaacaa aggaaaaacc
     7801 aacagatgca caacttaagg acatggaatt tggtatgaga gtagtaaaaa atatgaaatc
     7861 aaatgcaatt gcaatagtaa aaaatggaca aactctagct ttaggttgtg gacaaacatc
     7921 aagaatttgg gcattaaaaa atgctcttga aaataacaaa gataaagatt ttacaggagc
     7981 tgttttagcg tcagacgcat ttttcccatt tgatgattgt gtaacattag ctcatgaata
     8041 tggaatatca gcagtagttc aaccaggtgg ctctataaaa gataaagatt caatagaagc
     8101 ttgtgacaag tatgatatgg ttatggtatt tacaggaata agacacttca aacactaagg
     8161 aggatattat gaagatattg gttgtaggcg gtggcggaag agagcatgct atatgctgga
     8221 aactaagcaa agaaaaaaat gtagaaaaaa tttattgtgc accaggtaat gcaggaattg
     8281 caaacgtagc agaatgtgta aatataggtg atactaatat agaagaactt ttaaaatttg
     8341 ccaaagaaaa tgaaataggt ctgacaatag taggaccaga agtaccacta gttatgggaa
     8401 tagtagatga gtttgaaaaa gaaggattaa gagtatttgg acctaataaa aaatgtgctc
     8461 aacttgaagg aagtaaagct ttttcaaaag aatttatgat aaaacataac atacctactg
     8521 caaaatataa agaatataca aacttagaag aagctatatc agaaatagat agttttggat
     8581 atccagtagt aataaaagcg gacggattag ctgctggaaa aggtgttgta atacctgaaa
     8641 atagagaaga tgctatagca actttaaaag aaatgatgtc agataagaag tttggagctg
     8701 ctggagataa aatagtaatt gaagagtttt taaaaggaat agaaacttca attctagcat
     8761 ttgtagataa tgatacaata gttcctatgg caagtgcaaa agaccataaa aaagtaaaca
     8821 actatgagca aggtccaaac actgggggaa tgggaacttt ttcacctagt gaaatatata
     8881 cagaagaatt agcaaataaa gtaaaagaga cagtattaga aaaaacttta gaaggcttca
     8941 aaaaagatgg acttaatttt aaaggtattt tatttgttgg tcttatgata actgaagatg
     9001 gagaaaaagt acttgaatat aatgtaagat ttggagaccc tgagacacaa tctgttttat
     9061 ttagattaga aacagattta catgagataa tggaagctat actagataat aagttaaaag
     9121 atatagaaat aaactatagt gatgatgaag ctgtatgtgt tatgcttaca tcaggagggt
     9181 atccagacag ttatgaaaaa gggaaaatta taactggtct tgaaaacttg gatgatgata
     9241 tagtagtatt ccatagtggc actaagatgt ttgatggtaa tttggttacc aatggaggaa
     9301 gagtaattgg tataactgca aagtcaacta cagttaagga tgcagcagaa aaagtttatg
     9361 aaaacataaa gaagataaac tttgaaggaa tgcactatag aacagacata ggaagataat
     9421 ttttctaaaa tggaggataa ggtatgttga atactgaaaa taaagactca atggttagaa
     9481 gagtattagt tgaaaaaaga gaaggttttg accttgaggc taaagcttta aaaaaagact
     9541 tagtagaaag tttacacata gataatatag aaaatttaag aatattaaat agatatgatg
     9601 tagaaggaat atcagaagaa gtttatgaaa atgcagcaaa gacaatattc tctgaaccaa
     9661 atttagatgt agtatattat gaagaaatac caaaattaaa tgatgaaaga gtatttgcaa
     9721 tagaatttct tcctggtcaa tacgaccaaa gaggtgattg ggcagctcaa tgtgtacaaa
     9781 ttgtaaatca agggataaga cctgctatta atacagcaaa agtttatata ttatcaggca
     9841 aaataactga tgaagagttt tctaaaataa aagattactg tataaatcca gtagatagta
     9901 gagaagcatc tttagaaaaa ccagaaacgt taaaaatgga aactgaaata ccaacaacag
     9961 ttgaagtatt agatggattt atagatttag atgaaaatgg attaaaaaca tttgtaagtg
    10021 aaaaaggatt agcaatgact ttaggagact tacaacacgt tcaaaaatac tttaaagata
    10081 cagaaaagag aaatccaact ataacagaaa taaaagtatt agatacttat tggtctgatc
    10141 attgtagaca tactactttt atgactgaaa tagaaaatgt aaagatagaa gatggtaagt
    10201 ttaatgatat agtaaaagaa gcgtatcaaa tgtatcttaa ctcaagagac aatgtatatg
    10261 tgaacagaca taaagatata tgtttaatgg atatagccac tgttgcagta aaagaattaa
    10321 agaaaaatgg gaaattaaat gacctagatg aaagtgaaga aataaatgca tgtagtataa
    10381 acgtagatgt tgaagttgat ggtaagatgg aaaaatatct agtaatgttt aaaaatgaaa
    10441 ctcacaacca tccaactgaa atagaaccat ttggtggagc agctacttgt ttaggaggag
    10501 ctataagaga cccattatca ggaagaagtt atgtttatca agcaatgcgt gttacaggaa
    10561 gtgctgaccc aagaacgact ttagaagata ctttacctgg aaaacttatg caaagaaaaa
    10621 taactacaga agctgctcat ggatatagtt catatggtaa ccaaataggt cttacaactg
    10681 gacaagttgc agaagtatat gatgaaaact ttgttgcaaa gagaatggaa ataggtgcag
    10741 ttatagcagc agcaccaaaa gagaatgtag taagagaaag acctgaagca ggagatgtaa
    10801 tcgttcttct tggaggaaaa acaggaagag atggctgtgg aggagcaact ggttcatcta
    10861 aagaacatag tgaagagtca atcttaactt gtagtgcaga agttcaaaaa ggagatgctc
    10921 ctaacgaaag aaaaatacaa agattcttta gaaataaaga agttgctcaa atgataaaaa
    10981 gatgtaatga ttttggagca ggtggagttt gtgttgctat aggagagatt gctgatagct
    11041 tagatataaa cttagactta gttcctaaaa aatatgatgg acttgatgga actgagcttg
    11101 caatttcaga gtcacaagag cgtatggcag tagccataaa aaaagaaaat aaagataaat
    11161 ttatacaatt agcagtagaa gaaaacttag aagctacgca tgtagctaca gtaacagata
    11221 caggatattt aagaatgttc tggaatggaa aagcaattgt agatataaat agagagtttt
    11281 tagatacaaa cggagtaaaa caaactactg atgttcatgt tactaaagta gatgaagaaa
    11341 atacattctt tagctctaat gaaatagtaa aagatgttaa gtgtgcaagt atgaaagaca
    11401 agtttacaaa agtactatct gaccttaatg tttgttctca aaaaggatta gtagagatgt
    11461 ttgataatac aattggtggt aatacagtac ttatgccatt tggaggaaag tatcaagcga
    11521 ctccaacaca aggtatggtt gctaagatac cagtacttgg aggagaaact aatacttcta
    11581 caataatgac ttatggatac aatccaaagg taggaaaatg gagcccattc catggtgcct
    11641 tgtatgcagt agtagaatct gtgtgtaaat tggttgctat tggaggaaat tatagtacaa
    11701 caagacttac attccaagag tattttgaaa aacttggtaa caatccagaa aaatggggta
    11761 aaccattctc agcactttta ggagcatttt atgcacaaag taaatttgag atacctgcta
    11821 taggtggaaa agacagtatg tctggtacat ttaaagatat tgaagttcca ccaacattag
    11881 tttcatttgc tgttgacaca gtagatgcga agaaagtagt atctccagaa tttaaaaaag
    11941 cagactcaaa agtagtaatg ttatgtgtaa acaaggcaga aaatgatgtt gtagattttg
    12001 aggaattaaa gagaaactta gataaagtaa gagaacttat acatggaaat aaagttttat
    12061 caacatatgc attaggattt gcaggtgtag gtgaagcaat aagtaaaatg gcttttggta
    12121 ataaaatagg atttaagttt agtgaagagg ctgaaaaagc atttacagat gataaattat
    12181 ttgaggctag ttatggaaat atagtacttg aattagcaaa tgatgattta agtatgttag
    12241 aaggatacaa ttatgttgtg cttggaagta cagttaaaga aactagtata tttatcaaag
    12301 gtgaagaact tgcattagat gaattatata aagcacattg tagtacttta gagcctatat
    12361 tcccaactaa aacagaagaa gtaaaatcaa agatagaaac tataagttat atatcacaag
    12421 gagaagctaa aaaatcatca ttaagtatag ctactccaag agtatttata ccagcattcc
    12481 ctggaacaaa ctgtgaatat gactctgcaa gagcatttga aagagcagga gctaatgcaa
    12541 gtataagagt atttaagaat ttaacttata aagacataga agattctata gatacaatag
    12601 taaacgaaat aaaatcttct caaataataa tgttaccagg tggatttagt gctggtgatg
    12661 agccagatgg ttctggtaaa tttatagcta ctgtatttag aaatcctaga gtgcaagaag
    12721 ctataaatga atttttaact caaaaagatg gactaatgtt aggtatctgt aatggattcc
    12781 aagtattaat taaattaggg ttagttccat atggagaaat aagagttcca agtgaaagtg
    12841 ctccaacact tacttacaat aatattggtc gccatcaagc taagattgct agaactagaa
    12901 tttcatctaa taaatctcct tggttagctc aaactaatgt tggagatatt cataatatag
    12961 caatttctca tggagaaggt aagtttgttg ccagtgaaga tgttatgaga gaattaattg
    13021 ctaatggaca agtagcaact caatatgttg actttaataa tgaagctact tatgatattg
    13081 agtttaatcc aaatggttca ttctatgctg ttgaaggtat aactagtgct gatggtagag
    13141 tgtttggtaa aatgggacat tctgaaagaa ttggtgagga agtatataag aatattatag
    13201 gtgaaaaaga ccaaaagata tttgaatctg gagttaaata ttttagataa agctttgatg
    13261 tttaattgat agctagaata tataatttag atatttagat ttaaagagat gtaataatat
    13321 gatgataatc atttaatatt acatctcttt tttatttatc taagaaataa taagttcaac
    13381 ctaagttaaa atacaagctg tgttataatt aattattaag taaaattgaa tatttattgg
    13441 aggacaacat aattaatgaa aatattaata acagggtcta atggtcaatt aggaaaagaa
    13501 ttggttaacc aattagaagc aatcaatcaa agtataaacc aaccaaaata tgttatatta
    13561 gctacaacaa gaagtgattt ggacatatcc aatcagacta atgtagataa ttttattttg
    13621 cataataaac ctgatgtagt tgtaaactgt gcagcatata caaaggttga tgcatgtgaa
    13681 gataatatcg aaattgcata caaaataaat gctttaggag tgagaaatct agcaatagca
    13741 tcagaaaaag ttaatgctaa gcttattcac atatcaactg actatgtatt caatggtttt
    13801 tctaaatatc catataggga agacaataaa actgaaccca attctgtata tggaaaaagt
    13861 aaacttatgg gagaaaaatt tgttgaacaa ttctcacata agtactttat attgagaaca
    13921 gcatggttat atggtaatgg gaataatttt gtaaagacca tgataaaact ttctttagaa
    13981 aataaagagg ttaatgtggt taatgaccag tttggaactc caacaagtac agtagactta
    14041 gcaaaaatta taataaaaat catggaaaca gaacattatg gagtttatca tgctacatgt
    14101 gaaggtgagt gtagttggta tgattttgcc aaaaagatat ttaaactaaa aaatatagat
    14161 ataaaagtaa atccaattaa gagtaacgaa tttaaatgta aggctccaag accactatat
    14221 tctgtattgg ataattttat gttgaagtta attggtttaa attcttttag aaagtgggaa
    14281 gaatccattg aagaatattt agaaagatat gatataaatg aaaagtaaat gtattatttt
    14341 gagaaaagaa aataagatat tataaaaaat ataaatattt cttttattta tccgataatc
    14401 ataatatgac aaaaacaaat ttaaggatgg aaaaagatga aaggaattat tttagcagga
    14461 gggtctggta caagactata tcctataaca aaatgtatat caaaacaaac acttccaata
    14521 tacgataaac caatgatata ttaccctatg tcggttctta tgttggcagg gatacaagat
    14581 atattaataa tatctacacc aagagatata aaagcatttg aagaattatt tggagatgga
    14641 agttcactag ggcttaacat aacatatgca attcaggaga aagcaaatgg aattgcagaa
    14701 gcgtttataa taggagaaga atttatagga aatgacagag tgtctcttgt attaggggat
    14761 aatatatttt atggatatgg atttagtgaa aggttggaga atgcagttaa aagaaaagga
    14821 gcaactatat ttgggtatca tgtaagtaat ccaaattcgt ttggagttgt agaatttgat
    14881 aaggatttta atgtattgtc aatagaagaa aaacctacag ttcctaaatc taattatgct
    14941 ataccaggat tatattttta tgataatgat gttgtagaga tagcaaagct agttgaaccg
    15001 tcagatagag gtgaattaga aataacctct ataaacagtg aatatctaaa acgaggaaaa
    15061 ctaaaagtgg aacttctagg aagaggtatg gcttggcttg atactggtac acataaaggt
    15121 ctattggatg cttctaatta tgttgaagtg gttcaaacaa gacagggact gtatatagca
    15181 tgtttagaag agattgcata tacaaaagga tatataagta gagaacaatt aatgaaacta
    15241 gccaagccac tgataaaaac tgaatatggt caatatctat taaaattggc tagtgaagat
    15301 atgtaatatg gtagataaaa tttattataa attttattaa gggagtttat tataatggga
    15361 aaaatcaatg ttataaagac taaaatagaa ggattatata tagtcgaacc aaatgtattt
    15421 tatgatgaaa gaggatattt tatggaaagc tataataaaa aggattttat agagcagggt
    15481 cttgatatgt gttttattca agataatgag tctagctcaa gaaaaggcgt tttaagagga
    15541 atgcattttc aggttaaata tcctcaagga aaattagtca gagttacaga gggagaagtt
    15601 ttcgatgttg cagttgattt aaggaaagat tcacaaacat ttgggaaatg ggaaggtgta
    15661 atattgtctg ataagaataa aaaacaattt tatattccag aagggtttgc acatggattt
    15721 ttagttttat cagaaaaagc agtatttagt tacaaatgta caaattatta ttacccagaa
    15781 tttgagaatg gctttatatg gaatgacaag caaatatcta ttgagtggcc tttaaaagga
    15841 attgaagaaa tatttttatc agaaaaggac aaaaaacaaa aaagttttaa agatatttgt
    15901 acaagacgtt aataaaaatt tattagaatt aacatttagg agaaaaaata tgaaaaaaat
    15961 actgataact ggaggagcag gatttattgg gagtaatttt atacattata tgcttaacaa
    16021 gtatgtagat tattttattg ttaacctaga cttgttgact tatgctggta atttagagac
    16081 attaatagaa atacaagaca attccaatta taaatttgtt aaaggagata tttcaaatag
    16141 ggagcaggtg tataagctat ttgaagaaga aaggtttgat atagttgtta actttgctgc
    16201 tgaatctcat gtagataggt cagttgagaa tcctgattta tttattaaaa caaacattat
    16261 aggaacacaa gtacttttag atgcatctat aaaatatgga gttaaaaggt atcatcaaat
    16321 atctacagac gaagtgtatg gtgatttacc aattgataga aaggatttat tctttacaga
    16381 acaatcttct atcaatccaa gttctccata ttcagcttct aaagcatcag cagatttatt
    16441 ggtaagttct tattatagaa catatggatt gttaacaact atatctaggt gttccaacaa
    16501 ttatgggcca tatcattttc ctgaaaaatt gattcctctt atgattttaa atgctttgga
    16561 aaacaaacaa ttgccagtat atgggaatgg ggaaaatgta agagattggt tacatgtata
    16621 tgaccattgt actgctatag acttaataat acataaagga aatatagggg agatttacaa
    16681 tataggaggt cataatgaaa gaagtaatct agaagtagta aaaatgatat taaatctttt
    16741 aggtaaatct gaagagttaa tatcctatgt aaatgataga cctggtcatg atttaagata
    16801 tgctattgat gcaactaaaa tagagaatga gttaggttgg aaggcaaaat atgactttga
    16861 tttgggtata aaagaaactg ttaagtggta tatagaaaat gaatcttggt ggaaagctgt
    16921 tttatcagta taactttaaa atttagaaag gggcgtttta tattgaatga gataagttca
    16981 ctaattaata tattagcatt gactcaatta tctggtagta atactacaaa tcaatgtaat
    17041 tgtacatata ataattcatc tggatttgat atgattatga tgaccttgtt aaaagcatta
    17101 tcacaaaata atcaacatac ttctaatagc tacaatttat tgtctaattc tgagaattta
    17161 tttaatgaac ttgataatgt agtaaataat accactagta gatttataga tgttgataca
    17221 aaagataaaa atgtaaagtt gagaattgaa aatgctgtaa atcaagcatc aaaaaaatat
    17281 aacgtagatt caaatcttat aaaagcaata attaaagttg aatcagattt taatccaaat
    17341 accgtttctt ctgctggtgc taagggtctt atgcaactta tgccagaaaa ctgcagagac
    17401 ttaggggtta cagacccttt taatatagaa cagaatatag atgctggaac tagacatatt
    17461 aaggaataca ttgatatgtt tggagggagc atagaaatgg gattgatggc atataatggt
    17521 ggtcctggaa gaatgaaaag tagaggagta gaatcaatct ctgacctgta taaaatgcca
    17581 aaagaaacac aaaattatat tcctaaggtt atgaaatatt atagagggta ggctttatta
    17641 tgggaataaa tatagataag ctaaacataa gtccaagtat aaatatggag gttaaaaaac
    17701 taaaagagag taataaattt tctgacaaat taaactcttt aaaacaatct tcttcattgg
    17761 aagatataaa acgaaatttg gaaagtgtaa aaaaggcagg agaaaggctt gtacttactc
    17821 aaaactatgg cgatattagt atatataaaa atgcagtaaa agaataccta aaatctgttg
    17881 tagataatat gtattcactt gataaaaata gtagcttttg ggagcatcag tattataaga
    17941 atgtaaagat tgttgatagt aaacttgagg atatgactag taagttaatt agtgaagaaa
    18001 aagaaaacat agatattgtt tctactgttg acatgataca aggcttattg atagatatgt
    18061 atagataagg ttatacaagg agaaaaattt tatgaatagc aaaaaagagg atatatatga
    18121 attgaatttt gggcaattaa tagaagaaaa atctggtgtt atagaagaaa atcaaaatgt
    18181 ttttaatgca aaagtaaagg tagctgtttc tataggaaat acaacagaaa caataaaaaa
    18241 tatattagat ttaaaagaag gctctataat aaaattaagt aagaatgtgg atgaaaaatt
    18301 agatatatat gcaaacgata gattgtttgc ttatggagaa agcattatta caaatgagaa
    18361 gttatctgta agattatcta aaatagaaga ttcagatgta aattagcatt ttaaatatat
    18421 ccctttagtc tattctgtat gagtttagct aaggggatat ttttataaaa aatttaaaat
    18481 atgtgtgaat tatataaata tttttatttt atgagcgata actaaattat aagtatgtaa
    18541 ttttggaggt gaaactatgg atattaaaaa tgtaagttca aatattgtag tgaataatta
    18601 tttaaagaat acatctggta taaaaaaagt ggaagaggtt aaaaaaatta ataaaacaga
    18661 caagatagag ttatctaaat ttgcaaagga aatggcaagt gtgtcaaata tgagtgatga
    18721 gaatattaga aataaaaaag tcgatgaaat aaaaaatgca ttagaaaatg gaacttacaa
    18781 aataaaacca aaagaaattg cgaaaaaaat gatagaggat atgcgaggat aaagtcatga
    18841 ttacagactt aaaagttata atatatgaag aaaaaaatat aattagtaag atgatggaat
    18901 tattaaaaga acaatttgat tatatagttg aaaaagactt agaaaattta aatatgttaa
    18961 atcctaaact agaagatatt agcagggagc ttgcatccat agaaataaag agaagacaac
    19021 tttttggtaa tgatatttca atgagtgaag ttgttgaaaa tagtaatgat ggatatttaa
    19081 aagaaatata tacagacttg aaacgcattc ttgctttagc taaaaatcaa caagaatcaa
    19141 atgattctct aataaagaaa gaacttattt ttacgaaaaa aatgattaat ttcataaaac
    19201 cagctgataa gcaaactaca acttataatt cttatggaaa tattagaaaa taaatattag
    19261 gaggagaaat atggcaggat tattttccat tttaaataca gctaattcag gaatgaatgc
    19321 gcaccaaaaa gcaatacaga caatttctca taatataagt aatctagata cagacggtta
    19381 ttctaggcaa aggaccgagt ttgctacaaa tagtccaatg tatatgccta gtttgagtaa
    19441 ttcaattgca agaggacaat tagggactgg agtacatgta acggatgtaa caagagctag
    19501 aaatagtttt tatgattacc aatttagggc agaagctcat aagtatggta agacagtttc
    19561 aaaatatgat tattacaata ctatagaaac tatactaaac gaaccatcag actatggaat
    19621 atctgcaggt atagatgatt tttttaaagg atgggagtca ttatcaaagg atataaatag
    19681 tgacagtaaa aaaagtctag tggtagaaaa cgcatctaat ttagcaactt taataagtga
    19741 aagttataag aagcttgata agttaaaaga agatatagat tctaatatag acactgagat
    19801 aaaacaaata aatgacatgt taaaaagtct tgaagattta aataaatcta ttgatattat
    19861 atctggttct ggctctacac caaatgattt gcttgatgaa agagatagaa ttttagataa
    19921 cttgagtttt aaactagact ttgaaaatag tgatgttaaa aatatgcttg cagatggtaa
    19981 attagaactt aatgaattaa aaaatccaga tggaacttgg aaaacaggta tatcagggac
    20041 cttacaaggc ttgtttgaaa tgcatggtaa gattgataca tataaaagcg atttaaaaga
    20101 tgtatctgat ggattagcta aacagataaa tgatgtttat aatacgtctg caggaataac
    20161 agtaacagat ttttttataa cttcaaatgt agatggtgaa gatattataa agataaatcc
    20221 agctataaag agtaacccaa atgaattaaa gcttactgct gatgaagctt caaaaattgc
    20281 taagttaaag gatgaaaaaa tagatattgg ggtggctggt ggaaaagtaa gtacaataag
    20341 tgaccactat aaagcctttg cagaatcaat cggtttagat tctcaaaaag taaatcaaga
    20401 tgaagcaaat caacgtaaaa ttataaataa tattgataac tcaagaatga gtgtttcagg
    20461 tgtatctttg gatgaagaaa tgacagagct tataaaaata caacgttcat atcaagctag
    20521 tgcaaaagtt atgtcaacag ctgtgcaact actggatgtt gtaataaatg gaataattta
    20581 atagaagggg gaatttataa tgagagtcag tacaggtatg atgtctagca gctatctaaa
    20641 ctcactacaa gataatctac aaagattgga taaggttaat agacaagtta atacaacaaa
    20701 agaaataaac aagctatcag ataatccata taaagcaata aagatattaa actcaaaaag
    20761 tgaaataaag actatggaga cttatgttga gaattgtaaa gatacaggga attggttaga
    20821 aactactgat actgcattag atcagcttgg aaaattatta tcagacataa agaaaacttt
    20881 ggtggcaagt ggtgatggtg catactcaga tgatgaatta aagactctta gtaatgaaac
    20941 taatgaaaaa atgaaagaaa ttgcaaatgc tttaaatgca acacatgaag ggaagtacat
    21001 attttcaggt tcaaatacgg gggtaccacc tgttgaatgt atagataatg ctgatggttc
    21061 agtgagttta aagtttaatt ctagtctaaa tcttaataaa ttaaatgact ctttgagtat
    21121 ggatatagct caaggaataa gtgtagatta taacgttaaa ttgagtagcc ttggatttga
    21181 cccaacaaaa actgacccat ttgaagagtt aaataacata tcaaaaaaat tagcaaatcc
    21241 agatgctgat gctataaaag agcttacaac aacttgtttg ggcgatatgg aacaactaat
    21301 agaaaataca gtaaatgtta ggtctatata tgggacaaaa gcaaatacag tagaggctat
    21361 gaaggaaaaa aacgatgata gtttgataca gttaaaggat attttgtcac aaaatgaaga
    21421 aatagattat ggtgaaaaac ttgttcaatt aaaggcagca gagttaactt atcaagcttc
    21481 actacaaaca ggaggaaagt tatttaatgt atctatatta gattacatat aataaaataa
    21541 cgcagatatg atgaaggtta cattaaaaaa aggtatatta ggttttgaaa atttaaaaga
    21601 atatgagctt ttagatatag aagataatga ttatttaaaa gaatttaatt ctactgaaga
    21661 agaaggtata ggatttgttg ttgtatctcc atttgagatt atcaatgaat atgaaatagt
    21721 tttaaatcag gaaacaatag aaaaactaga agtgaaatct ccaaaggatg ttgtattatt
    21781 taatataatt actcttggtc agacatttga agaatcaact gtgaacatga aagctcctat
    21841 agtgataaat ataaaaacta attttggaat gcaaataatt ttacaggatg ataaatattc
    21901 aataaggcat ccattattga gaggtgataa tggatgctag taatttcaag aaaaaaagat
    21961 gaagcagtac ttataggaga aagcatagaa gtaaaaattg taggagtaga tggaaacaat
    22021 gtaaaactag ctatatcagc gcctaacaat ataagtatat taagaaaaga aatatacgaa
    22081 aaagtaaaga gtgagaatat aaaagctaca aataaaaata taaaaatttt aaagtcatta
    22141 aaataataag cttggaggaa gtaatatatg tatggagaaa atccttataa ttcttataaa
    22201 caaaatgctg tttttatggc atcaaaggaa caattgttac ttatgcttgt tgatggagca
    22261 gtaaaatata ccaaaatagc cagagcagct atcttagata aaaatacaca gaaagcgcat
    22321 agagaacttg taagagttca ggatatattt acagaactaa tggttacatt agaccaaaat
    22381 gcaggacaat gggcaaagga tatgtacaaa gtttatgatt ttgtaagata tgaactttca
    22441 agagccaata ttagaaaaga catccaggta atagataatg tgttacctgt aatagaacaa
    22501 attaaagata catggcatga agctgataaa aaaagtaaag aagaaagaag taggtacaaa
    22561 taatggaatt aaatttagct gaattagata agttatcaaa agaggaatta ctattgatgc
    22621 ttgtagatgg cacagtaaaa tataccaata tatccaaaga agctctttta aataacgact
    22681 atttgaaagc acataatgaa cttgtaagag ttcaaaatat atttacagaa ctaatgacta
    22741 cattagacca aaatgcagga caatgggcaa aggatatgta taaagtttat gaatttataa
    22801 aatctgaatt agcaatagct gatgaaaata aagatattaa aataattgat gatatattgc
    22861 caatagtaaa acaaattaga gatacatggc atgaagttta caatcaacta aaaatataat
    22921 tagatggagg gataaaggta tgtcaagtat aagtcctata agagttacag gtctttcagg
    22981 aaattttgat atggaaggca taatcgaagc tagtatgatt agagacaagg aaaaagttga
    23041 taaagcaaaa caagaacaac aaatcgttaa atggaagcaa gaaatatata gaaatgttat
    23101 acaagaatca aaagatcttt atgataaata tctaagcata aattctccta atagtatagt
    23161 aagtgaaaaa gcatactctt ctacaagaat aaccagttct gatgaaagta ttatagtagc
    23221 aaaaggttca gctggtgcag aaaaaataaa ttatcaattt gcagtttctc aaatggctga
    23281 accagcaaaa tttactatta aattaaattc aagtgaacct attgttcgac agttccctcc
    23341 aaatgccagt ggagcgagtt ctttaactat aggagatgta aatataccaa tatctgaaca
    23401 agatactaca agtactattg taagtaagat aaactccctt tgcgcagata atgatataaa
    23461 ggcttcttat agtgagatga caggtgaatt gattatttca agaaaacaga ctggttcgtc
    23521 atcagacatt aatttaagag taattggaaa tgacaattta gctcagcaaa ttgctaatga
    23581 taatggtatc acatttataa atgatgctgg tggaaacaaa gtggcaaatg tatatggaaa
    23641 gaatctagaa gctgatgtaa ctgatgaaca tggaagagta actcatataa gtaaagaaca
    23701 aaattcattt aatatagata atattgacta taatgtaaat tcaaaaggaa ctgcaaagtt
    23761 gacttctgtc actgatactg aagaagctgt taaaaatatg caagcatttg tggatgatta
    23821 taataaactg atggacaagg tctatggttt agttactact aaaaaaccaa aagattatcc
    23881 gcctcttaca gatgcccaaa aagaagatat gacaactgaa gaaatagaaa aatgggaaaa
    23941 gaaagctaaa gaaggtatac ttagaaatga tgatgagtta agaggttttg ttgaagatat
    24001 tcaatctgca ttttttggag atggaaaaaa tattattgca ttaagaaaac taggtatcaa
    24061 tgaaagtgaa aattacaata aaaaaggtca aatatcattt aatgcagata ctttttcaaa
    24121 ggctcttata gatgatagtg ataaggtata caaaacacta gcaggttatt cttcgaatta
    24181 tgatgataag ggaatgtttg aaaagctaaa agatattgta tatgaatatt ctggaagttc
    24241 aacttctaaa cttcctaaaa aagcaggtat agaaaaaact gcttctgcta gtgaaaatgt
    24301 atattcaaaa caaattgcag agcaagaaag aaatataagc aggttagttg aaaaaatgaa
    24361 tgataaagag aaaagacttt atgctaaata ttcagcctta gaatctttgt tgaatcagta
    24421 ttcttcccaa atgaattatt tctcacaagc acagggtaat taattatgga taaattaaaa
    24481 gaaaaattaa atttatataa agatatatct ttacaaatta taaatttgat tgaaaaggaa
    24541 gaatatataa agataagtat taagttaggt gaaagacaag agattataaa tagtgtaagt
    24601 gaaattgata gaaatgattt tatacagctt tataatagaa tggaattaat tgaaattgat
    24661 agcaggataa gagatatttt acaaggacaa ttattagaag taaaaaaaga attacatgag
    24721 tataagctta ctaaacaagt gaacacaatg tattataact taaatagaga aaaagtaaat
    24781 atttttaata aaaaagtata aagttatgta ccatcttgtc cgattatata aatgaagaat
    24841 taataaaaaa gattaaaagt agaaatgaca aggatgtcaa ctatactaag gagggtaaaa
    24901 taatgagagt taatacaaat gtaagtgctt tgatagcaaa taaccaaatg ggaagaaacg
    24961 taaatgcaca aagtaagtct atggagaagc tatcttctgg tgttagaatt aagagagctg
    25021 ctgacgatgc tgctgggctt gctatatctg agaaaatgag agctcaaata aaaggtttag
    25081 accaagcagg aagaaacgtt caagatggta tatctgttgt acaaacagca gaaggtgcat
    25141 tagaagaaac tggtaacata ctacaaagaa tgagaacttt atcagtacaa tcttcaaatg
    25201 aaactaatac tgctgaagaa agacaaaaga tagctgatga gttactacaa ttaaaagatg
    25261 aagttgaaag aatatcaagc tcaattgagt ttaatggtaa gaaattactt gatggaagtt
    25321 ctacagaaat aagattacaa gttggagcaa actttggaac aaatgttgca ggaacatcta
    25381 acaacaacaa tgaaataaaa gttgctctag taaatacttc aagtataatg agtaaagcag
    25441 gtataacaag ttctacaata gcaagcttaa atgcagatgg aacttctgga acaaatgcag
    25501 ctaaacaaat ggtatctagc ttagatgtag ctcttaaaga attaaataca tcaagagcaa
    25561 aattaggggc acaacaaaat agactagaat caactcaaaa caacttaaat aatactatag
    25621 aaaatgttac agcagctgaa tcaagaataa gagatacaga tgttgcttca gaaatggtta
    25681 acttatctaa aatgaatata ttagttcaag catcacagtc aatgcttgct caagctaatc
    25741 aacaaccaca aggagtttta caattattag gataaaataa ttttgtatat tggatataga
    25801 agaaagggta aggctttgct ttactccttt ctttttttac aaatatactt ttgaaaggaa
    25861 aatttatatg ttacttagta tagttatgat tgttaaaaat gaagaaaaaa tacttgaaaa
    25921 aactttaaaa tcattaacca cattaagaaa ttctatagaa agtgaactta taatagtcga
    25981 tacaggttct acagatgata ctataaaaat atctaagaag tacacggaaa aagtgtattt
    26041 tcataattgg aataatgatt tttctagtat gagaaatata tcaatatcct atgctaaagg
    26101 tgaatggtta cttatattag atgcagatga aatactaatt gattcttcaa ctattgtaaa
    26161 attttttaaa gatggtcttg ataaaaaatt taattctgct tcaatacaat taaaaaatct
    26221 ttactcatat gataaaaaat tatatggata ttgttcagtg cttagacttt ttaaaaacgt
    26281 tgattttaga taccatggta aagtacatga acaaccaata tacaaaaacc ctatatttaa
    26341 taatgttgct gattttgaac attatggata tttgtttgaa gatgaagaaa taagattaaa
    26401 taaggtgaaa agaaatgaaa aactattatt tcaagagtta aaagagaatg ataattctcc
    26461 atatacaaac tatcaattag ggaaaaattt tattatatta ggaaaatatc aggaggcttt
    26521 atactatctt gagaaatctt atgaattata ttctaaacta gaattggcac ctggttactt
    26581 gataacaagc cttgtaaaaa catatttata tttaggaaaa cataagaagt gtgaaagatt
    26641 gtgcttaaag tatattaaga aagacatgaa taatattgat atatattatt atattgcaca
    26701 agcacaagta gatttaggaa agtatgaaaa tagtatagat tcgtataaga gatatattta
    26761 cttgttagat aattatgaaa taagtacaca agcaaatagt ttattttcag acactgatac
    26821 tgtagggctt agagatgagg ctattattac actgataaag atttattata agcttgaaaa
    26881 atatgagttt gtaatttcag agtataataa cattgaagat gtggaaaaga aaaagaatgt
    26941 gtactttagc ttatttatgt cactatataa attgaataga tttgaagata taaaaaatta
    27001 ttataaagaa gtttcaaatt ctaaaattga aaaaaatagt ttttatagaa atatagaaga
    27061 agttataaat aatattaaag aggatgaaaa agagtatgta tataaaatcc tttgtgacat
    27121 tgaaggtaat tatggcattt taaatcaaat aaggataaat aaatgtgtat ctatagataa
    27181 atgtaaagaa atactcaatg aagaaaagga aataatttat gcatatatta taaaaatagc
    27241 ttttgaagag aagattgatt tactagatat tttttatgaa atggaatatg tatggataga
    27301 gaaatatcta aaatatcttt tagcattaga aagaagtttt aatttagtac tatataagta
    27361 cataattagt cgtccaaata catcagatat ggaaaagata agagtatata aagctatatc
    27421 taaagtagtt ttagaaagta taagcttaag tgatgaaaaa tataaggaga ttttttatct
    27481 ttatataatg tattcttata agtacataag atacatatat agcaatttaa gtgattttga
    27541 attaataaaa tttgtttgta atgatttaga taagttcact atagaattta agcatctact
    27601 tgatattaaa aataaagtaa ataatgctaa tgaaaaatta gagtatatac atagtatgag
    27661 gaaattacta aatgagtatc ctttttataa taaaataata aaaatactta taggtgaatt
    27721 agaagaaaat ataaaagaaa gtgaagaatt taaggattta aaagatagtt ttattattag
    27781 tatagaaaat atgattgaaa ctggcaaaat aaatgatgcg aaattattgg tagatgacta
    27841 ttcaaaaaca tttgtggatg atataaagat tttaaatata aagggaattt tatacatgtt
    27901 tgaaaataag cttgataaag ctgattttat gttaaaaaag gcattatcat tagatgtaga
    27961 aaatgaagat actatatata atatagaata cttaaaaagt ttaagataag tcaaaaatag
    28021 gagaattgaa gaatgaatat accaatagtg gttaatgaaa aatctaaaga cataataaaa
    28081 gattggcaat atacatgtac aaatgaagat ataaaattta caagcataat aatattgaca
    28141 tataatcaaa tagaatatac taaattatgt attgaaagta ttaggaaatt taccccaaag
    28201 aataaatatg aaataataat aattgataat aactcttctg atggaacagt tgagtggtta
    28261 aagggacaat ctgatataaa atctgtgtat aataacaaaa acttaggatt tccaaaagga
    28321 tgcaatcaag gtattgagtt agctactggt gaaaacatat tgttgttaaa taatgatgta
    28381 atagttactc caaattggct ctataatttg aataaagctt tatggtctca agataatata
    28441 ggtgctgtag gacctattac gaatgcatgt tcatattatc agcaaattga tgttgattat
    28501 aagtcaattg aggacatgtt tatatttgca cacaaaataa ataaatctaa tattaaccta
    28561 tggaaatata gattgaagtt agttggattt tgcatgttaa taaaaaaaac tgttctggat
    28621 aatgtagggg ttttagatga attattcaca cctggaaatt ttgaagatga tgatttatct
    28681 tttaggatga tagagtcagg atataagtta ttattatgcc aggatacttt tatacaccat
    28741 tttggaagtg tgtcttttaa agaaaatcgt aataaatata cagatataat gtatattaat
    28801 agaagaaaat ttgaaactaa gtggggattt aatccagaat atagtggaat gataagaaca
    28861 gatttgattt ctaaaataga tgatagtttg gaggcaaata ttaatgtttt agaaatagga
    28921 tgcggtatag gggctactct tttagaaata aaaaatatat ataaaaatgc atcaatatat
    28981 ggaatagaaa ttagtgagtc agcaggtaaa cttgcaaagt atagtgcaga tgtacttata
    29041 gcaaatatag aaaaagtaaa attggattat aaaaaagatt tttttgatta tataatattg
    29101 ggagatgtac ttgaacattt gattgaccca tggaagatag tcaatgaatt gaaacaatat
    29161 ctaaagaagg atggttatct ggtatctagt ataccaaata ttatgcatgt ttctgtttta
    29221 agaaatcttg tgttaggtaa ttttacatat gaagattcag gaattttgga caagactcat
    29281 ttaaggtttt ttacattaaa tgagataaca aaaatgttta atgatagtaa ttacataatt
    29341 aatagtatta cagctactag tatgccactt tcggaaattg ataatagctt cattgataca
    29401 atatgtaagg aaagctgtaa agaaatgaga caacagtacg aatcttatca atatatagta
    29461 aaagcctcta aaatcctaga tactaaaaga tattctagta ttagtatgat taatttaaaa
    29521 tacgctttaa tgagaattga taatgaatta gatgtagata gtaatttaag ttatatattt
    29581 gataattata atataactga accatgtttt gttgatgata ttgaatatct aattgataca
    29641 tttgtgataa ataaagcaac tctattaaat agattaggag ttgaggcatt taacagaggt
    29701 ctaggagatt ttagtataaa catgtttatg acagtattag agatggatag agatgatatt
    29761 gactcaatat ataatataac aagtgtatta tgtgaattag aagaatttga tactgcttat
    29821 aatttaatta aaaatagtag cgaaaaagta cagagtgaaa gtgatataca agagatactt
    29881 tgttttattg aggggaagaa atatgaataa tgataagata tgttttataa cctgtgtaaa
    29941 tgatgaaagg ctttatgaag aatgtcttgt atatataaat agcctagaca ttcctaaaaa
    30001 ctttagtata gaaacagtag ctttaagagg agccgattct attgcctctg cttataataa
    30061 agctatgaga gaaacagatt ctaagtataa ggtatactta catcaagata cttttataat
    30121 taataaaaat ttcatacatg atattttaga gatatttaaa aaaaatacag atgtcggaat
    30181 gattggtgta gctggagtaa aagatatgcc tgtgaatgga atttggtggg attctgataa
    30241 aaaagcaggg aaagtatatg atagtcatac aggtaaaatg gatatttatg aatttagtaa
    30301 ctttgaagaa tgttttaatg aagttatggc tatagatgga ttaattatga ttactcaata
    30361 tgatgtattt tggagagagg ataagtttga tgggtggcat ttttatgatt tgtcacagag
    30421 tatggagttt agacaaaata aatacaaagt tattgtacca aaacaaaata agccttggtg
    30481 tatgcatgat tctggagtag taaatataaa taatggatat gatgaatata ggataaaatt
    30541 tgtaaaagag tacataaatc ttgatttata tagagaaaat ttttatgaat ttgataagaa
    30601 gaaagcaagt accatactta agagtaataa gcatgtaatg gattgtatga aagaggagct
    30661 tacagaacaa ttaagattaa agaattacaa ggatgtttta ggtattgttt ctaaaattgc
    30721 tcatttttct gtttttaatc atactggttt gtattcttgt gaagaatgtg agagagcatt
    30781 gctagaatgt gcaaataatt taccagaaat agaaaatacg aaattattta caaaaaaaga
    30841 tttaaaaaga agaaaagtat tacatgtttt aagtgaagga tattcaacag gaggtcatac
    30901 aagactagtt aaaaattgga ttgaaattga caaagactct gttcattcag ttgtaactac
    30961 atggcaatca gatacactgc cagactggtt attaaaagca ataaatgata gtggtggcga
    31021 agttatatct ttggatttaa tttcagatga ttatttaaaa agagctgtag ctttgaggaa
    31081 aatagcttat gactgggctg atatagttat tttatatgtt catatgtggg atacaatacc
    31141 tgttgttgct tttggagttg atgggaaaat acctatttta catgttaatc actatgatag
    31201 tactttttgg ttagggacaa gtattgcaga tattgtcatt gattttagcg aagctagtca
    31261 attaattaca ttagataaaa gaggcataga taaatctgaa atattaccaa tgccattaaa
    31321 agaaaaagaa gtattttcaa aatctgaagt tagaaaacga tataatttag aggatgatgt
    31381 gacaataata ttgactattg ctagtgaaag aaaatacaat agtgtaaatg atattaatta
    31441 ctttaaaatt gctaaaacat tgattgaaaa tacagataat acaattatta ttgttgtagg
    31501 agttgataca gagaatctct attggaaaac tttaagtaac gttacagata atagagttat
    31561 atgttttgga acaacagcaa atatagacga tttttacaag atttcggata tatatatgga
    31621 gtctttcatg gtaggaagtc atacttcaaa actagatgca attttatatg atttaattcc
    31681 tgttaagttt aaaaatgaag tttcaccaat ttttacaaat atgtggaatt ttatagataa
    31741 gtttgattat aagaatataa aagaggttat agatatgata aaaaggtaca atactagtga
    31801 atttgacagg gataggataa aagaaaaaca atcggaaata aaacattttg ttatagataa
    31861 acactgtatt gaaataaaaa actatataga caaaatatat aatgaagcta atcatcataa
    31921 agttaagtat gatttatata aaaatgatga aatcgaggac tatcagcttt ttgtagcatt
    31981 atatggctat atggtaaaaa ataaaaacat gtcataggtg gtaaaatgaa caatattcat
    32041 atcaataaat ttgaaaaaag ctgtgaaaga aactgggatt attttgtaga aaataaatct
    32101 ataaatggta catttctgca aactagaaat ttccttaatt atcatgagga gggaaaattc
    32161 actgaccact cattaataat atgtaaaggt gaagaaatac tagcagtcgt acctgcatgt
    32221 gaaacttatg aagatggtga aagaatattt ttttctcatt tagggagtac ttttggtggt
    32281 attataataa gaagtggttt taatgatatt aggcatgtaa atgccattac aaataagtta
    32341 gaaatatatt tacgggaaca aaatttcgat aaagtatatt taaaaaatac atcaagaata
    32401 ttttgtaaag aggatacttc attactagaa tattttttat ttaagaataa ttacatgttt
    32461 tatgatgaat taagtatgtt tttagaatta agtaagtata aagaagatat attagccaat
    32521 tttaaataca gtaaaagaag agattttaaa tattctttga agaataatct tacctttaaa
    32581 agactgtata gtgatgaaga tatagtttgt ttttttaatt tactttctaa ttgtttagat
    32641 agtaaaggag ctaaagtaat acattcagta gaagaacttt tggagtttaa aaataataga
    32701 ttaaaagata ttgtagaatt ttatgcagta tatattgatg acattatgat ttgtgggagc
    32761 atggtattta actttcaaga aagagtttat catactcaat atctagcatc aaattcgaca
    32821 tataataaat attatccaat gatattttta tactataatc taataaaaga tgctttagag
    32881 agaaatttta agtatctttc ttttggaatt agcactctaa atagaggcaa atacttagac
    32941 gagggtttag ctacatttaa agaaggtttt ggttcaagtg caatttgtaa cagaacatac
    33001 tataaaaata taaataagtg agaatcatgt tttatagagt ttttagaata tagtaaatat
    33061 ctagtactct aacattacat aaaaataatt agtttataaa gaaggtttgt atatgaaaag
    33121 attaatgatt ttaggctcaa ttaagtattt tgagaatatt gttatatcag ctaaaaaaga
    33181 gggaatatat acgattgttt gtgataatag aattgatact cctgcgaaaa agatttgtga
    33241 tgaagcaata gatgttgatg tatttgattt tgataaaata aaaagtatag ctatagataa
    33301 aaagatagat ggaattttaa ctggatttac agattcttta atgaaaccat atgtttatat
    33361 tgcaaatgaa ctaaatttac catgtgtgat ttcttgcaat caacttgaat ctgtaactaa
    33421 caaggctatt atgaaaaaat attttaaaaa taatgcaata cctacaactg attactgtat
    33481 tattgaaagt ctaaaagatt tagaaaaaat acaaggatta aattttccac ttgtaataaa
    33541 acctgttgat ggttatggtt caagaggtgt atattttgta tcaaatatag aagaattaat
    33601 agaaaaattt gaatattcta aggaagcctc acaagatgga caagtaataa ttgaggaatt
    33661 ttatgaaagt gaggaaatac aaggactagc ttgggttcat aatggagagt cacatgtatt
    33721 ttatattgga gatagagagc ttgtaaacat acatacagga agagctggaa aaccagatag
    33781 attactttat ccatcaaagt attgttttca atatgaggag gaaataaaat ctatatatca
    33841 aaatataaca caggcttttg atataaaaaa tggacctctt tatgtacaaa tgttagtggg
    33901 agcatatgga ataaaggtat ctgaagtaat gccaagatta cctggaggtt gtgactatat
    33961 ggctatttct caaataacag atttagacat aggaagttta tttgcaaact ttagtgtgaa
    34021 taatgaagta aattttgatg aaataaagaa atataatatg catctatcaa aatgtgtata
    34081 tgcattacca atatacataa gacccgggac aataaaaaag ataaataata tagataaaat
    34141 agaaaactta gattatgtca ctcaatttct attactagta aaagaaggag atacaataga
    34201 attatatgaa gatgagagac aggattgtgg aagagtttat ggaatagcaa ataatatatt
    34261 tgatgcaaat ataaaaaaga aatgtattca tgaaatgata gaaatacttg atgaaaataa
    34321 tgaaaatatg atagaaaatt tttaaataag ggagtatgat agatatgaag ctaataactc
    34381 atgaacaaat tatgtcatta aacatttctc agaaacaagg atatgagtgg ataaaagaat
    34441 ctttcttaac aaaaaaagat tgtcaattac caccaaaaat aagcatggta gaagaaggac
    34501 atgtatttta caatgtaatg ccatccctaa atcataatca tatgattggt ggaataaaaa
    34561 tggttacaag attgccaggg agaaatccaa gtttaaactc agagatattt ctatacaata
    34621 tggaagatgc taaattaaag gctattttgg atggtaatta tattacagct tttaggactg
    34681 ctgctgttgc tgccttggct atcgatacat ttgctaaaaa agattttaat actattgcta
    34741 ttatgggttt aggtgtaact gcttctgcta taatgaatat gctttcatat actcttaaag
    34801 ataaaaatat aaatataaag ttacttaaat ataaagacca agcagagttg tttgtaaaaa
    34861 agtatgaaaa aaatgaacaa tttagttttg aaatatgtga tacacatgaa gaacttattg
    34921 tagattcaga tgtagttatt tctactgtga catatacaga tgaatattta tcagaattta
    34981 aatggtttaa aaaaggtgct ttattattac ctgtacatgt tatgggattt ggaaatgttg
    35041 attatctatt tgataaagta tatttagatg attataatca tttgaaacat ctagaaaata
    35101 tagatagata taaatattct tgtgaatttt atgatgtttt aagtaaacaa gctaaaggaa
    35161 gagaaaatga tgatgagaga ataatatctt acaatatagg tttgtcaata catgatatat
    35221 tatttgcaaa taaaatttac gaattgtgtg aaacactaag ctgtgaagaa atagaattaa
    35281 aagaaccaaa agaaaaatat tggatatagt ttatttcatt catatttaca atagtttatt
    35341 gtaaatatga atatgaagta atatattgtt agaaaattag catgaatagg atagataaat
    35401 ttatggataa atataattta attaggttcg tatctattgg aaacgaatat ataggaaatt
    35461 tagttgcatt agaatcaaat aaagtaatac cttttgatat aaagagagtt tattacatat
    35521 atgatgtacc aaacaatgta aagagaggat ttcatgcaca caaaaacttg gaacaagtac
    35581 tagtttgcct aaatggaagt gtgaagataa aatgttatga tggtgtaaaa gagactatat
    35641 ttaatttaca taaaaatgat gttggattat atataggaac gggagtgtgg catgagatgt
    35701 ttgattttga tgaaaaaact gttttaattt ctatagcatc tgaacattat aatgaagaag
    35761 attatattag agactataaa gaatttttaa agtatttaaa taatgtgtag ttattataca
    35821 attagtgatg tattttctta attaaataaa tttaagatag ccacatagag aatagataga
    35881 ttaggatgtg aatttattgt tggttaaatt taataattta ttaaaacagt tccaaactca
    35941 taaagaagaa tatgaacaga agattaagga tgtaatggaa agtggatatt atatccttgg
    36001 aaatgaagta aagcattttg aagaagaatt tgctaactat gtaggtagca aatattgtgt
    36061 tggtttagcc agtggtttag atgcactgat aattgctttt agagcattag gaataagcaa
    36121 aggtgatgaa gtaatcgtgc aatcaaatac atatattgct agtgttatgg gaatcagtat
    36181 aaatggagca acaccagtat ttgtagaacc aaatgaatat tataatatag attcatctaa
    36241 gatagaagaa aagataaata gcaaaacaaa agctatatta gtagtgcatt tatatggtca
    36301 agcaagtaat atgaaagata tacaagaatt atgtgataag tataacttgt atttaattga
    36361 agattgtgct caatctcatg gagctaaata tgatggaaaa atgacaggaa catttggtga
    36421 tataggttgt tttagttttt atccaagtaa aaatttgggt gcatttggag atgcaggagc
    36481 tatagtaact agtaatgagg aaatagctga taaagtgaaa attcttagaa actatggctc
    36541 agaaaagcga tattataata aatttgtcgg atataattca agattggacg aaattcaggc
    36601 aggtttatta agagtaaaac ttaaatatct aaatgaaatt gaaattgaaa aatcaaaaat
    36661 cgtagataga tatcttaatg aaattaataa tcccaaagtc atacttccaa agatagaaaa
    36721 taattgtact catgtatggc atttatttgt tttacaagtt gaaaaacgag atacatttat
    36781 ggaatactta aagaaaagtg gtatagagtc tataatacat tatccgatac caccacatct
    36841 atctgaagca tatgcttatt tgggatataa aaaggggagt tttaatatag ctgagaacta
    36901 ttcagataaa gttgttagta tacctttatt tattggtatg gaagatgaag aagttagtta
    36961 tataattaaa attataaatg aatattaaac tactcataat aatatcaaaa ataaattttt
    37021 tatatatcat ttatttaaat ttcgttaatt gacattttta aatattgata tattgtacaa
    37081 ataaaattga aatatatgga aaaatataga attaagatga gatttgtctt atatttttat
    37141 aaattaaaaa tattttcaaa gagtttatta taaaattgta aactatagtg tttataatct
    37201 ttgtaattat tggtaattaa atttaaaaaa taaaatattt aattatacac aaaaaagata
    37261 tttaaaaaat ttgttattta ttgtatactt aagttaaaac taaataggca aatctagaga
    37321 aatctagtga cgcaaagcta tagggactaa ggtttatata cataaactat gtcagccagt
    37381 tgccaaaaag agtcctaggt gtattgtata cctaagaaaa gtctataatg actgcctttt
    37441 tggcagtcat tttgttatgg aaaaatcact ttatttcagt agaaaataca cataataaca
    37501 tattttacca attataacat aaaataaaga aaaattatct caaaaagtta ctattttaca
    37561 aaaaagagca acttttcgaa gaaatattta aatacatatt aaaatttttt tatattttca
    37621 tgggacttca ttaaaaaaat attagttttc ttactaaatt gatacattat tgtattaatg
    37681 taatggaaat gcgattaatt taaataaata aagaagtcat tttttgtaat atagcaactt
    37741 catttttttt attaataaac aaaatagata aaatatattt tgaggagggg tgagtgtgaa
    37801 tacatatgac attataaaaa tgggattaga tgcaactaat ctaagaagtc agacaatagc
    37861 aaataatata gcaaatataa atactgaagg atataaaaga cattatataa cttttgaaga
    37921 aacactaaat gatgctatgc ctaaaataga agaaaaaaca gacaattcta aaggtttaag
    37981 agtagatggt aataatgtag acatagaaga agaaaaagta aatcaagcaa tggcaacatt
    38041 acaatataat gctttgataa gttttgcaaa tggaaaaata gcaatgacca aatcaataat
    38101 aagtgggagg taattagaag atgagtgtgt tcagtggaat gagaatatct gctagtggat
    38161 taacagcaga aagtttgaaa atggatatca tatcatccaa tgtagctaat ataaatgcta
    38221 caagaggtcc aaatggagaa gcatatagga gaaaagttgt ttcatttgaa gaaaactatg
    38281 ataataaatt aggtatgcta ggagtaaaag ttacatctgt tgaagatgat aaatcacctc
    38341 ttaaagaagt atatgaccca tctcatccag atgcaaagcc aaatggatat gtagaatatc
    38401 caaatgtaaa tatattggta gaaatgacag atttaataac agcttcacga gcatatgatt
    38461 ctaacgtaga tacattgaat gctcagaagt ctatgatatc aaaagctttg gaaataggaa
    38521 agtagggata aattatgcca attacacaaa ttaacaattt aatgcaaggt gcaaagttag
    38581 ataatttgat tggagaagca aagccattaa ctcttaataa taaagaagaa aaaaagaatt
    38641 ttgaagatgt aataatagat actatagata aagttaattt tcaacaagta acagcagatg
    38701 atatgaaaga aaaatttata aaaggcgaag atgtttctat gcatgaagtt atgttaatag
    38761 gtcaagaagc acaactatct atgcaatatt taatagaagt tagaaataag attcatgatg
    38821 catatcaaga aatgaataag gtgcaaattt agccttttga acaggagtaa taatcaatga
    38881 taaccagttt taaaaataag attaaggagc aagttgctaa atctaggaca aagataagtt
    38941 ctttaaaaaa gggaactaaa atagcattag gtataggggt tattgctata tgtttagcgc
    39001 tagtatttac agcaatatct gcgagcaaaa ataagtatgc agtcttattt tcagaactag
    39061 atgctcaaga tgctgcagat atatcagcag agctagagtc taaaaagata gatactaagg
    39121 taaaaggaag tacgatttat gtacctagaa cagaagttga taagttaagg ctggagttag
    39181 cgccaagtct tacaggtggt tctaaaggat ttgcactaat ggatgatagt tcatcaatag
    39241 ggcttactga tgaagaattt cagattaaga aacaaagaat gatacaaggt gaaatagaaa
    39301 aaacaataaa gagttttcca caagtggaag acactagagt acatataaca tttggagagt
    39361 catcagtatt tgagaaggag gctgttccag ggagtgcagc agtttatttg atgctaaaac
    39421 cagggacgac tttagaaaaa aaccaaataa agtctgttat ggcacttata tcaggaagcg
    39481 ttacaaatat accagagaaa aatgttcagg ttattgataa caaaatgaat ttattatctg
    39541 aaggtatttt ggaggatgaa aatgttgatg aaaataatca accaataaat agtggcatta
    39601 gtgttgataa aaataaggca tctgaacaag cattgaataa acaactagaa aagtctattt
    39661 tagaaatgct agaaccgata tttggtaagg gaaaggtgaa agctacagta aatgctgatt
    39721 taagttttga tacagctgaa aaaactgaga taaaaattga ccctgataaa gttgcaataa
    39781 aggagacaag gtcgaaaaat tcatctaaat ctgctgcaaa taatgttcaa ggtgtagatg
    39841 ctaacatgaa taaccaagga aataacaatg gtactaatac agaagatagt ttagatgaga
    39901 gttttgagta tgaaacaggt aagattgaaa ctcacactat agttgcgcct ggagaactta
    39961 atagattgac agcttctgtt gcaatagatg gaaaaatagc taaaggtgtt caagctgatg
    40021 tagaggatat tgttaataat gctataggta tggatggagc gaggggagat actcttagcg
    40081 ttgtttcaat ggtatttgac ccagaaggta agaaagaggc taaacaagag ctggaagaga
    40141 ttaaaaaaga aggatttaaa aagaacataa taaaagcagt tattggagta gtagcagtaa
    40201 tagcagttgg agctattgga tacttaatat ataagaaaag aagtgaacga gaagatatgg
    40261 attatgaaga tgaagattat atttctaaat ctgattctgt tgataggaag gataatcctc
    40321 tattaggaga tgacccagaa ctgacattag aggaagctgt taaaatgtat gcagaagaaa
    40381 agccagacca agtaacagag ataataaaga cttggttaaa tgagtaaggg ggatagaaag
    40441 tgtccacgga aattacaaat gttaatgcgt ttgacttaag tgatataaat gaaagtgata
    40501 agaatgagaa ggtagaaggt gagggtttaa aaaaagctgc tgtattatta atgacattag
    40561 gcccaaatgt gtctagtgat ataataaaaa gcttgcctga taaacaagtt caaaaaatag
    40621 gtttggaaat tgcaaatatt tcttcaatag cttcaaaaga aagaagagaa atcttaaaag
    40681 agtttgtaga aataaatagg gcaaaagatt atgttataga aggtgggctt gaatatgcaa
    40741 gagagttatt aagtaatgct ttaggaaatg ttaaagcaaa caaattactt gaaggtatat
    40801 caataaatac aagtacaaag ccttttaaac atattataaa actagatgta aagaagatat
    40861 tagaaatact taggaatgaa agtgcacaaa ctatagccgt tttacttgca catatggaac
    40921 cagaaaatgg agcagaagtt ttatcatact tagattttga tttacaaaat gaagtagcta
    40981 tgagaataag ctcaatgggt tcaatatctc cagaagtaat aaaggtaatt gaaagttcat
    41041 tagaagataa attacattca ataagtggtg atgattttaa tgattatgga ggggtgtcta
    41101 ccttagttca aatattgatt aattctgata gaaaaacaga aaagaatatt ttgggaacta
    41161 ttgaagaaca aaacccggat ttagcagctc aaattaaatc tcatatattt gtctttgaag
    41221 atattgtcaa gttagatgat ataagcatac aaaaagtgtt aaaagaagtg actatgaaag
    41281 atttagtata tgccttaaaa ggtgtagatg atgagatttc agatgctata tatagaaatc
    41341 aatcttctag agcagcagat gcacttaaag aagaaatgga aatggttggt gttataaagg
    41401 ttacacaagt tgaggcttct caacaaaaga tagctaatat cgtaagaaaa cttgaaagag
    41461 aaggtgccat aactattgta aggaattttg gtggtgactt tgttgaataa taagattatt
    41521 aaaagtaaaa aagcattata taaaggagtg ctagatttaa ccataataga taaagttaga
    41581 gtgggagaat caaatgtaaa taaagaaaat gattgtagat ttagggatga ggtaataaaa
    41641 gaagctatag aatctgctga gataagaaag aatgagatat tagaagaagc aaaaatgaat
    41701 gcacaaaata tagaaaagca agcatatgaa aaagggtata gtcaaggtca aaaaaatgga
    41761 tatgaagatg gatataaaga gtcatatgat gaatataccc aaaaagctaa agatgaagca
    41821 gattttataa aaaatcaggc agacttaata ctattacaag ctaatgagaa gatgactgag
    41881 tacataaaag aaaaaaataa agagattgta agacttgcta ttaatatggc tagttctgtt
    41941 ctaaaaaagc atttcgaaga tgaagaatct atgagtgatt tgttaaagca aattattcaa
    42001 gattatgaag gaagtagttc atttatagta agatgtaatt ctttctataa agataatata
    42061 gagaaagagt ttgaattatt caaagaggaa acatcactaa aatcaagtgt atttgttatt
    42121 gcagatgata gtatagataa aggcaatgct attatccaaa aggaaaatgg aagaataata
    42181 gttggtattg attgtgctat ggaaaaacta aaagaagaat tgcttggtga ataaagtatg
    42241 tataaaactg atatatctat agattttgac aaaataaata agaaaataga aaatttagaa
    42301 ctcactatat cagaaggtag agtaaagaag ataataggac ttactgtaga agttgaagga
    42361 ataaaagctt ttgttgggga gttatgcgtt atatacaacc aagttaataa accagtgaat
    42421 tgtgaagtag taggttttaa agataaagaa gtcatattaa tggcgttggg agaattaaca
    42481 ttgatagcac ctggttgtaa agttatttct aaggggatac ctttaagtgt tatgtgtagt
    42541 gataatttac taggtaaagt acttgatggt cttggaaatc ctatagacaa ctcagatgct
    42601 gttttaggag atagatacaa cctgaacaat gaacctcctg acccaatgaa gagaaaaaag
    42661 atacgaaata taatggaaac aggtgtaaga gcaatagatg catttactac ttgtggtgaa
    42721 ggacagagaa tcggcatatt tgcaggaagt ggagtaggta agagtacgac tctaggtatg
    42781 attgctagga atgcaaaagc agatgtaaat gtaattgctc ttattggaga aagaggaaga
    42841 gaagtactag attttattga taaagattta ggtgaagagg gaatgaaaaa atctgttgtt
    42901 gtgtgtgcaa catcagataa agcccctcta gttaggttaa aaggtgctct tactgctact
    42961 gcaatagcag aatattttag agaccaaggc aaaaaagtaa tacttatgat ggattcagta
    43021 actagatttg ctatggcaca aagagaagtt ggtgtagcaa taggagagcc accagctcaa
    43081 aaaggatata caccatctgt atttgcaatg ttgccaaaac ttatggagag aacagggaca
    43141 tcagataaag gttctataac tgcattttat acagtattag ttgatggaga tgactttaat
    43201 gagccaatag cagatacaac aagagggata cttgatggtc atatagtttt atctagagac
    43261 ttggcaaata agaatcacta tccttctata gatgtattaa acagtttaag taggcttatg
    43321 aatgaaattg cttcaaaaga agacataaaa atagcgtctt ttgcaagaga catgcttgct
    43381 gagtatagag aagcagaaga tttgataaat ataggtgcat atgcttcagg tacaaacaaa
    43441 aaaatagatg aagcaatcta ttatcatgag catattatta attttttaaa acaaggaata
    43501 aatgaaaaga gttcttttaa tgaaactata agtagtttaa gaagaatctt tgaataaaca
    43561 atttaaaaaa atatttgaat aggttgtgat ggaattggat aaaaatttta agtttagatt
    43621 acagaaagtt ttagacttaa aaataaaaga tgaagaagag ataaaaatgg aatttgctaa
    43681 gattcaacaa aaaaaaatag atatagaaac taatttagaa aacttagaaa gtaattacag
    43741 caaatattct ataagtaaaa ataatgataa tgttcaaaat caaaaaataa ctattaacta
    43801 tttgctagct ttaaacaact ctataatgga tttatcagaa gaactggata agtcgacaaa
    43861 tgaacttgaa aaagctagaa aacagcttat aagcaaacag atagagagaa agtcattaga
    43921 aaaattaaaa gaaaaaaaat atggacagta ttataaagaa gaacagttaa aagaacaaag
    43981 cactaatgat gagtttgcaa gcatgagtta tttgagaaat agacaagttc tataaaataa
    44041 taggaagtga ggatattatt gtatgaagat acaagcagat tcttataata ttattaaaga
    44101 tattgggaat agaaaaaact catctaagaa taaaaatata aaaaataata aatttgaaga
    44161 taatctatat aagacaacag accataaaaa tgttaaagat agaagagaaa caagtaagca
    44221 aaatgttagt tcagatagac cgggaaatag tgataatgag tgtcatttag atgaagataa
    44281 aagtaatcac ttagaagatg aaaatacata tgaaaaagat tgtagtaaga ataatgaagc
    44341 tttacagcaa ttactgaatc ttttaaaaga gaattataaa aaagataaag atataaacac
    44401 tatattgaat aatataaaaa aactaagtat atcagatgaa ttaaaacaag aacttaagct
    44461 taataaaaat atattgaata aaattgcaaa tcaaaattta gagttaaatg gagctaatac
    44521 aaataaccct aatgatatag aaaatttaga cataatgaag ttaagagaac ttttagaaaa
    44581 taatgctagt gaagatattc aagtaattag taaaactaca gaaaatgata ctaaaagcat
    44641 agacttatac agttttgata gtaatagaat ggatactctt aactcaaata aacagaaaga
    44701 tgatagttct gatattttgg aaaaactagc agggttaaat ggaaataaga gtggaaattt
    44761 tggacaagta ataaataaaa gcgttgatat gaataaaatt aaaaatgata atgttaattt
    44821 aaaacagata gaatctaatg taatggatga ttctataaaa gctattaagc atatgaaaac
    44881 aaatgatata caagaattga caattaaatt aagaccaaaa gaattaggag atatgaacat
    44941 acaattatta aaagatggtg aaagtatgag agctgttgtg actgttttca ataaagatgt
    45001 ctttgactct ataaataaaa acatagcaga tttaaagcaa catcttgaac ttacaaatgt
    45061 aaatataaaa gatgtatcag tgcaaatgca tagcgataat acaaatacat ctgatacctt
    45121 tgataaagca tttgaacaac agaatagaca aaataaccaa gaaaacatga gtaatcaaaa
    45181 tacaaatgat aagcgtaaca atgtagtcat agaagatgag attaaagaaa atattattga
    45241 tgatgataga gtagatttac tagcttagta agggggaagt attgcatgta cggaatagca
    45301 acggctttgg caggaactca ggtaaactat aggtcaaata acttaagcca acttgaaaga
    45361 aatattaatg atattgccaa caaacaagtt agaagtaaag gaaatcagac agtaacagac
    45421 aatgggactc caattatagg acaaggtgat gatgctgata aagacttgtt tatgaagatt
    45481 cttgtagcac agatgggtaa tcaagaccca atgaatccac aagacccaac ggagtatgta
    45541 tcacaattag cacagtttgc aactttagaa aaaatgtcag ctatgaatga taagctagat
    45601 atacttttag ccttaagtaa ctctactcta ataaactctg ctttgagtat ggcaacatca
    45661 ttaattggta aagaagtaga agtatctggg gaagaagatg aagatgaaaa cattgtagga
    45721 gtagtaaagt ccacatacat aaaagatggg gaagtacact tagaattaga agtagatgga
    45781 agtgacaaaa ctgtagatgt taaatatgaa aaattactta aaataggaga ggtagaggca
    45841 aattcaggag aagaaaatga ctcttcagaa caagaatctc cagaagaagt ataatattaa
    45901 atgggaaaag aggtaaattt atgataaaag caatgtattc aggtgtaagt ggaatgaaag
    45961 caaatcaaac aaaactagat gtaatcggta acaatgtagc caacgctgga actacttctt
    46021 ttaagaaaag ttcagctaga ataacagatt cattttatca aactgtacta tatgcaagtg
    46081 ctccaacagc ggcattaggg ggaacaaact taggacaagt aggtgtaggt agtaagatat
    46141 caagtataaa caaagatatg acacaaggaa atgtacaacc aactaataga ccatctgatt
    46201 taatgataga tggagatgga tatcttccag tagtaagaca aggaacagtt atgtatacga
    46261 gagatggttc ttttaattta gatacaggat ttaaagcagc tgatggtgct ttgaagaata
    46321 ttaaaggtgg aagacttgta aatggtgatg gatatatgtt acaaggtatg atttatgatg
    46381 gggaatataa agctgatact ggagaatttg ttaaaaaggg tgatgctaaa ggaaaagagc
    46441 ctattgtaat accacttcaa agtataagtc ctaaggatgg aacagttcaa aatgtactag
    46501 agtataatat atcaaaggat ggaacagtag aatttttatt gagtgatggt caaagaactc
    46561 aatttgtcta tgatatacct gatggtgcta aggtaggaga tacacctgct ggaatagata
    46621 aattaaaagg tacaatacaa aaagtgcaaa catatgcatt ccaaaatcca gcaggactag
    46681 atgcagaagg aggaaacttg ttcaagccat cagcaaactc aggagaccca caaatagcag
    46741 gagctacagg cacaataata caaggagcta tagaagcttc caatgtagat atagcagaag
    46801 aatttacaga aatgataata gcaagtaggt ctttccaagc aaacagtaaa ataatatcga
    46861 catcagacga aatacttcaa gaaataataa atcttaagag atagtaggta catattatga
    46921 taagagtaac ggatttaaac ggaagaaaat acatattaaa ttcagatctt atagtgagaa
    46981 ttgactccgt gccagaaagc aggattctcc ttacaacagg agaaaaaaat cttgtaaaag
    47041 agtcagtaga tgagatagta gataaagtaa taaagtataa aagaaaaata aatgtaggtt
    47101 atattaggag tgaaaaataa tgaaaaaaac agattcacta acattcattg gactaatatt
    47161 atctacagta ttagttttat ttggagcagt aaaaggaagt agttcaggat tgaaaagttt
    47221 tttcgatttt gcatctatat taatcacagt atttgggtca tttggagctt tgatgattac
    47281 atttactatt gacgatataa aacttataaa agatgctcta caatactcat tcaagacaat
    47341 gaatatatcg aaattagact tattaaatca atttaaaaca ctttctaaaa aagcaagaag
    47401 agaaggactt ttatctatag aaagtgatgt aatgaaaata caagacccat ttatgaaaaa
    47461 aggattagag ttatgtattg atggtcttga aataaatgaa ataaggtcta tactagagct
    47521 cgaaatagat tctgttgaag aaaccaataa cagatattct aaactattta aaacttgggg
    47581 gactttcgca cctgcatttg gtatgttggg aactctaata ggtttaatac aaatgttatc
    47641 cgaccttaca tctccagatt taatagcatc tggtatggga aaagcattaa ttacgacatt
    47701 ttatgggtct ttacttgcca atatcgcttt gaacccaatt gcatataata tagatgagaa
    47761 gactgaaaaa gaaatttatg taaaggaaat gatgctggag gggataataa gcatacaatc
    47821 tggagagagc agcatagtag ttgaggaacg tttagctaca tacctttcaa ataatgagaa
    47881 gttagaaatt atgaaatcca ataaaaatac agaaagagca atgagtaatg gcgcgtaaaa
    47941 aaaataagaa aaaggatgag ataaatccag atgcatggtt ggctacttat gcagatacga
    48001 taacactgat tcttacattt tttgtgttat tgtatgctac atcagttgta gatatggaaa
    48061 aatttaaaaa tatagcagat gcgttaaaag gtcagttttc tgggacaagt atgtttagta
    48121 caggttcaag tacaagtgag aaatctccaa tagagagtgt tttagtggat aaaaatgata
    48181 agtcaaattt agaacaggat ttaaaagata aagttaataa ttctaactta caaaatagtg
    48241 taacagtcaa agatgatagt agagggattt tactagagct agatgattca attttatttg
    48301 actctgggat ttctgaatta aaagaagata gtaaagccac tcttaataaa gtatacgata
    48361 tgataaagat gatgaaaaat aagatagtta tagaaggcca tactgataat gtacctgtaa
    48421 aatcaagtac gcatgaatcc aattgggatt tatcttctag tagagcagta agtgttgtaa
    48481 gatactttgt agaagaaaag ggcatggacc ctaaactatt ttcggcaaca ggatgtggag
    48541 agtaccaacc tttggtatca aatgaaacag caaagggaag agctgagaat agaagagtta
    48601 atatacttat aactattgac taggaggaag aggtttgttc aaaaataaaa aaattattat
    48661 aattattttg atactgatta ttttctcagc aggagcaggt ttttttatat taggagaagg
    48721 tggaaataaa caaattgaca agattgcagg tttgtttatt ccaacaggga aaggcaaaga
    48781 tgaagtaaag accgaaaatc ttgacttaga agagatggta ttgaagctag ctgatgaagg
    48841 tgtaagatat ttaaaagtat caataactgt atcttatgat tcttcatata aagatataga
    48901 aaaaaatacg cctttaatta gggataatat tataaattgt tttatggcaa aaagggcaga
    48961 tgattttact gctgataatt taaagaacat aaaagaagaa attaaaaata cattaaatat
    49021 acaactaggt gaaaatgtaa ttcaaaatat atatttcaca aatatagtag tgcaataaaa
    49081 ggatggtaag acatgatact ttatttacta aaaatattaa tatgtatccc aataatttta
    49141 atattgatag tcttatcttt aaaaattagc caaggaactt tattaaaaaa atataatgat
    49201 aaatatataa aaatactaga tattgtaaat ataagtaaaa acaatagcat aataatttta
    49261 aaaataggtg aagaaggatg cattatggca tcttcttctt ctagcatgag taaaataaaa
    49321 gatttgacca aagaagaaat attaagaata gaaaacgaca ttaaagaaag aaattttaaa
    49381 attcaagatt ttaaaatgga aagaattaaa aagaaatatg atttcagtag atatattgga
    49441 aaatttacaa aaaaggaaga taagtaaatg gaactattat caaaattacc tttggctgat
    49501 gtaccatata caagttcaat gcaattgttt ttatttctaa ctgcattaat gtttttacca
    49561 tttgtaatgt tcatgatgac aagctttgtc agaatagtta taagtttatc atttttgaaa
    49621 tcagcattag gagcacagca agcaattcca agtcaaattt tggtagggct tgcaatagta
    49681 ttgacaatat ttataatgag accagtatta aatgagataa acgaaaaggc attacaacca
    49741 tatatgaaag aagaagttac tatggaagaa gctatgaagg aagcagaagg acctattaaa
    49801 gaatttttat taaagcaaac cagacagaca gatttagatt tatttgtaga gcaagctggt
    49861 ttaaaagaaa agaaattaac tcgtgaaaat ataccattat ctgttgtagt tccagcattt
    49921 gctataagtg aactaaaaac tgcttttcaa ataggttttt taatatatat accatttttg
    49981 ataatagacc ttgttgtggc aagtgttttg atgtctatgg gtatgtttat gttacctcca
    50041 gttatgatat cattaccatt taaattatta ttatttgtaa tggtggatgg atggaacttg
    50101 atagtaaaaa cattgatatt gggatttgga taggagaaaa atagtatgag tgaatttatg
    50161 ataatgagtg ttcttaaaaa tggcatgttt acaggagcta tgattgcagc tccagtgcta
    50221 attgtttctc ttgtagtggg gcttttaata agtgtatttc aagccacaac tcaaatccaa
    50281 gagcaaactt tgacttttgt accaaaacta atagcaattc ttttagtagt agctattggt
    50341 ggaagctgga tgttacatac tcttattagc tttacttcgg agatattcaa tatgatgtct
    50401 ctcataacta aataagtagg atatatatga tttttgtatt tattagaata gtagcattct
    50461 ttggaacatt aaggatacta tttccagctg gtacacctgc tttatttaag tcgctctttg
    50521 caatcattat atcaatcttg atttcaagta ctatgcaaat tgaatatgca acaaatatag
    50581 acaacattgt attgtttacc ttatatggta taaatgagac cataactggg attatgcttg
    50641 gatatataac caatctatgt ttttatagta tcagaatggc tggttctatg atggaccaac
    50701 agatgggatt atcaatgatt aatatgtttg acccaaattc aatgactcag acaactttaa
    50761 tcaataatct tatgaactgg acagcactta tgatattttt tagcatggat ggtcatcatg
    50821 ttttaattag aggcataagg tatagttttg agttaattcc aatagggaaa tcattcatag
    50881 ataataatat agattatata ataaacatat ttgtgcagtg ctttttaact ggattcaaaa
    50941 tagcaatacc tattgtactt tgtctgctta tggcagattt tatattaggg cttatatcaa
    51001 gaagtgtacc tcaactaaat gtaatgataa ttggtatgcc attaaaaata ctggttggta
    51061 ttgcattatt tatcatatca atacctttaa ttgtcaatca aataagtcat ttattaagtc
    51121 aaataccaaa gatgtatgag ggaacttttg cactagctcc tatgtttttt atgggttcaa
    51181 cagataaaac agaagaagct actccaaaga aaaagggaga acaaagaaaa aaaggtaata
    51241 tagcaaagag taaagaatta cccattgcaa tgactctact tgcattcact ttattagtac
    51301 ctacattatt ttcatatgta gtgaatacac ttaaatcttc tcttaattat tttttgagtc
    51361 tagattttta tatgaacata aattattcaa gtatagagaa attagttata gcaggattaa
    51421 tggatttttt taagatattt ttaccaatag ctattccatt cttagtttta ggtatagtcg
    51481 caaacctatt tcaagtagga atactgttta ctggtgaaac tttaaaaccc aatttatcaa
    51541 aattaaatcc aattagtgga ttcaaaaaca tgttttctat gagaagtttg tcaaccttaa
    51601 taaaagatac agcgattata tctattttgg cttacatagg atatacattc ttccaagata
    51661 attatttaga tatattaaag ttaggtaaca tatacctgcc aactttaatg tacacagtta
    51721 aagatttagt atattcaata ttaagtaaga tttgtgtagc tatgatagtt atagcagttg
    51781 cagattatgt ttatcaaaga tacagtcata aaaagcaact tagaatgaca aaacaagaag
    51841 ttaaagatga atataaaaac tcagaaggag acccagaaat aaaagctaag ataaaacaaa
    51901 aacaaagaca aatttcgtct caaagaacca tgcaagcagt accaagtgct actgtaatag
    51961 taaccaatcc cacccactta tctatagcag tgagatatga aaaagggaaa gaccaagctc
    52021 cagtagtggt ggcaaaaggt gcagattatt tagcttttaa aataagggaa attgcaaagg
    52081 gaaatgacat acctataata gaaaataaac ctattgctag gttgttatat aagcaagtag
    52141 aaatagacca agaaattcca gaggacatgt atcaagcttt tgcagagata ttagtagcag
    52201 tatataaaat caaaaataga tacaaagtcc ccaaaaggta ggataagtaa tgaataagtt
    52261 taatttaaag gaaaatatgg acgtaatagt ggcatttggt gttgtaggga ttgttcttat
    52321 gatgatagtg ccgttaccta catttatatt agatatttta ctggcaatta acataagttt
    52381 atctgtgcta attttactaa tgacactatt tacaacaaat gtacttgatt tatctatatt
    52441 tccaacagtg ttacttgtga caacactatt tagattggga ttaaatcttt catcaactag
    52501 attgatttta acacagggat atgcaggtga agttatagag gcatttggaa gttttgttgt
    52561 aggtggaaat tacgtagtag gaataattat attcttaatt atattaattg ttcaatttgt
    52621 tgttataacc aatggttctg gaagagtatc tgaagtaaca gctagattta cgttagatgc
    52681 catgccaggt aagcagatga gtatagatgc agatttaaat gcaggagtta tagatgacaa
    52741 aactgctaga aaaagaagaa aagagcttca gcaagaagca gatttttatg gctctatgga
    52801 tggagcaaat aagtttgtaa agggagatgc catagcaggt cttatagtaa cagcaataaa
    52861 cataataggt ggaattgtaa taggagctgt aatgctgaat atgactctta tgggtgcagc
    52921 acagacatat gtaagactta ctatagggga tggtcttgta agccagatac ctgctctatt
    52981 aatatctaca tcagcaggta taatcgtaac aagagcttct actgatgaaa actttggtgg
    53041 attagtaggt aaacagttaa cagcaatacc aaaagcagta atgatgactg gctgtgttct
    53101 aatcgtactt ggtatgatgc ctggattacc taaaccagca tttttttcac taggtatagg
    53161 tgctatagca gcaggttact ttttaggaag agaaaagaaa gatactttag aagacttgga
    53221 gtttgaaaaa cctgatatgg taaatccaga taaaaatgaa gtagaagatg taacaaactt
    53281 aataaatgta gaatcaatag aagtagaaat tggatatggt ttaatatctt tagctgatga
    53341 atcagcagga ggagatttac ttcagagaat agcatcaata agaagacaat gtgcaataga
    53401 catgggtata gtcgtacaac ctataagaat aagagataat ttacagttaa atccaaacca
    53461 atacaatata aaaataaaag ggaatgtagt tggtgggtat gagataatgc ctaatatggt
    53521 tttatgtatg gatcctatga atcaaggatt tagtatattt ggaataaaga caattgagcc
    53581 tacttttgga atagaggcac tttggataga aagtgacaag gtagaagatg cagagctaaa
    53641 gggttataca gttgtagatt catccacaat acttataact cacttactag atataataaa
    53701 atcaaatgca cacgaattac tgggaagaca agaagttaag actattatag atgcagcaag
    53761 agaaaattat agtgctgtag tagatgaatt gataccagat ttaatgacac ttggtgaaat
    53821 tcaaaaagta cttaaaaatc tgttaagaga aaaagtaaat ataaaggata gagttacaat
    53881 acttgagaca cttgcagacc agtctagaaa tacaaaagat atagagcttc ttactgaata
    53941 tgtaagaata gctttggcta gaagtatttg taataattta gttgatgaag ataaggcaat
    54001 tgtagtggct acattgtctc cagaaactga agaattggta tctaataatt tacaaaggtc
    54061 tgtaaatgga acttatccag cagttgaccc agaaaataca aataaaatat ttgagagtat
    54121 acaagaagta atgaacaatg tatatttcaa tcataatata ccagtaatag tagtatcacc
    54181 aaagataaga gctccattta gaaaattagt tgaaattgta tatcctaatt tgactgtatt
    54241 atcattaaat gaaataccta acgatattaa aatcaaagca gaaggtgtgg tgagcatata
    54301 tgatgacgaa aaagtataca gctaacacaa ttcaagatgc tatgaatcta gccaaaatgg
    54361 aattgggtga caatattaca ttaatagata aaaaagaggt aagaaaatct ggaataagag
    54421 gcattttttc aaagaaagat attgaattga ctattggatg ggaaaagaaa gataatttag
    54481 aacaaaaaga tttaaaacga gagatagaac aactaaagtc aattataaat aatatggggt
    54541 ttgataataa aaatgataat gatatagata aaatatgcaa gaatttacta aacttagatt
    54601 taaatcaaga aattgtagaa tttataaaag ctgatttaca agaaatgaag ttcaatggaa
    54661 ttgatacaag taaaaattta gtagaaagtc taaagaaaaa gattaaaata gaaaatcaag
    54721 caataaatgg taaaattgct ttagttggac caccaggagt aggtaaaacg actacaatag
    54781 caaagttggc tgccaaatta gtttttgagg aaaataaaaa agtaggagta ataactatag
    54841 atacatacag gattggtgct gtagaacagt taaagatata tactgatata atgaatattc
    54901 cttttaaagg ggtaataagc cctgatgaga tggaattggc acttgatgag atgaaagatt
    54961 gtgatgttgt attaatagat acaacaggta gaggctataa aaactctatg caaatattag
    55021 aaatcaaaaa tcttatagat aaagctgaaa ctgataatat acatttagtt ttgaactgta
    55081 caacaagaga aagtgataca aaagcaatta tagattcata tagaaatgtg aattttaaaa
    55141 gcttaataat tacaaagtta gatgaaacaa taacatatgg ctcaatattt aacataatga
    55201 attatgcaca aaaaccaata tcatatatta caacaggaca aaatgttcct gatgatatta
    55261 taaaacctaa tgaagataag attataagat tactattagg agttgaaagt atatgataga
    55321 ccaagctcaa attttgagaa aaatggcaat ggaaaaaaga ggttctgatg agattatagt
    55381 agagaatgag aatatgccta agataattac aatagcttct ggtaaaggcg gcgttggaaa
    55441 gagtaatctc gctacaaatt tgtctatatg cttaaccaaa cttgataaaa aagttcttat
    55501 attagatgca gatataggaa tgtctaatat agatataata atgggggtaa atgtaaaagg
    55561 gactataatt gatgtaatta atggcgaaaa aaatatagaa gatataattt cacagactaa
    55621 gtatggtgta aatataatat ctggaggttc tgcccttaat catatagaag actttacaga
    55681 agctcaaaga aataagttta tacatagcat agaacagatt cacaatgtgg attttataat
    55741 aattgataca ggagctggta tgagcaaaag cctattgtca tttatatact gtagtactga
    55801 atttttctta ataacaactc cagaaccgac atcattgact gacgcatata gtttattaaa
    55861 agctataagt aattttggca taaagaaaag tgcaaatata ataatcaata gggtaattga
    55921 tttagaagaa gcgaaatcta catacaaaag aataaaaatg gttgtggaca aatttctaaa
    55981 ccttaatctg gaattgtatg gatatataat agatgacaaa aaagtaggtg tatgtgtaaa
    56041 aaaacagata ccattcattt tagaatatcc tacaagtatt gcatcaaaat gtattatagc
    56101 tatagcaaag agaatggtaa gtcagtcaag agaagatatt gttgataata aaagttttct
    56161 aagaaagatg tttagtatat ttaaaagcta aggaggcgta gttaatgaat agagaagaat
    56221 taataaaaga gaatatgcct cttgtaaaga gtatagcaag aaaatttttt ataccaggga
    56281 aaggttttga atatcaagac ttagtaaata gtggagtcat tggattgatt gatgcaataa
    56341 ataaatttga tactgaaaaa ggagcaaagt tttctagtta ctcttatata aagataaaat
    56401 ctgctatatt agatgaaatt agaaatcaaa gtccaatttc taaacataat ctaactaaag
    56461 taaataagta taatagagtg gtagaaaagt tgcaatctaa attattaaga gagccaactt
    56521 catatgaaat tgcaaaagaa ttaaaggttt cagaaaaaga acttcatgat atcgaaagta
    56581 atatagatat gttaaatatt gtatcattaa actatgtaat ctttgaagat acaaatgaaa
    56641 ctgtacaaga tgtaataagt gatagagaag aggaagctcc agaaaatata atagaagaag
    56701 aagaaaagtt agagattcta tccaaagcaa ttagtaattt aaatgaaaga gaaaaattaa
    56761 tactttcact gtactattat gaagatttaa atctaaagga gatagggaaa gtgctaggtg
    56821 tttcagaatc aagagtttca caactccaca gaaaatcaat aagaaactta agaaacaaga
    56881 taaaagaact taaatattct atatagatgg tgattgataa gatgatacaa attatattaa
    56941 tagtagtgtc tattttaata atagtaacta tagttataaa tttacagaag gaatcaaaaa
    57001 ataaagataa cagatacttt gataaaatat ttgagcaaga atatgaagca aatgatagat
    57061 taataattgc agaaaaaaga agattctttt tagacaaagt acttgcagaa aaaagaatta
    57121 atagtcatat aaaagtttat gaaaattata acctaataaa ggctaatgaa gaaagaaagg
    57181 aaaacatatt tatagaatca aaaaaggaag taagacaaga aaatgagtta tctcttaaag
    57241 tgaaacatct tataagttca ggttatgatg atgtggaaat atgtaagatg ctagatattg
    57301 gaaaggggga actgttatta ataaggagtt gttacaaaat ataaggatat tattatgtga
    57361 taaaaaagta ttcttaggaa taggtattgg tatattaata tcaactttat gtataatgct
    57421 ttttagtaat aatgatatga gtaaggcaga gatagaaaaa aaggccagag cgttaggcat
    57481 gaaatataca agtgagatga aagttttaga atagatgata ctgtttagac atttacaaaa
    57541 aaggaggtca taatgtgata agaggattat atacagcagt ttctgctatg ataactaatc
    57601 aacaaaagca aaatgttgtt gtcaataacc tagctaatat ggatacaaat ggatataaaa
    57661 gtaaacaact tttgactaaa agttttgatg aattaaagtt ggagggttac aataactacg
    57721 caaatggaac taaacaaaag cagattatag gcgatataag tccaggtatt tctatggatg
    57781 aaactatcac aaattttaat caaggaccta taaaaactac tgataataaa atggatgtag
    57841 ctattcaagg taagggattt tttctagtta gtgatgcagc tggaaatcaa ttttacacta
    57901 gaaatgggaa cttcagaaca gacaatcaag gtgaccttat aacaagtgaa gggtattatg
    57961 tacttgggac gaatactgct actggtgctg taggtcatat aaatgtagga aatcaaaaat
    58021 ttgaagtggc aaaagataat acaatatcac tagacggaaa tgctatgtat aaatttaata
    58081 ttgtagattt taataactac aataacttaa aaaaagaagg agataactta tattctggag
    58141 gaggagctat gaaagtaaat aatgcactta caatacaaag tgcgatagag tcctctaatg
    58201 tagatatggt atctgaaatt aataatatga tgacaatatc aagagaatat gaggcaaatc
    58261 aaaagataat tcaggctatg gattctaaat tagcaaaaat agcaagtgag attggttcag
    58321 taagataggt aataggaggt gaatttttat gtacacaatg ttttatacta gtaaaacagc
    58381 tttatcagca aatcaaagta aactagatat aatatctaac aatatagcaa attctgattc
    58441 aacaggatat aaaaaaataa atatggaata ttctgattta gtggatgaag tactaaatag
    58501 accatcatac cctacaaatg gtaaagatat atcgactgga acaggagcta aggcaacagc
    58561 tcccatgaga aattatgaac aaggtgcatt ggctcctaca gatagtaaga gtaatttggc
    58621 gatagatgga gaaggattct ttagagtgat aagaaaagat ggtacatatg catatacaag
    58681 aaatggtgga tttaatgtag atgctttagg taagattgta gatgataatg gaaatatatt
    58741 agatgtccaa tttgatgcag gatataacta taataataca aatatagata gtacaaacct
    58801 gacagtttca agaaatggag agctattcgt agataataaa aaaataggaa aaattaactt
    58861 atatcaacct ataggaactc aaaattttat atctgaagga gatagtttat ttgtcgcaac
    58921 tgatgcagca cagattaaac aagttgagaa agtcgatata gttcaaggct atagagagag
    58981 gtcaaatgtt tctttacaag aagaatttgt tgacttaata gccactcaaa gagcatttca
    59041 aatgaactca aagggaataa agacagcaga tgaaatgtgg caaatagcga ataatttaag
    59101 agctaaataa ttatgtaagg agaggaatat tcatgaatga tatgaaagag tacgattttg
    59161 gcaaacctca gagttattca agagaaaatt taacttgttt aaatttttta ttagctgaat
    59221 tttgtaaaaa atataaaaac tatataattt atgaacttaa gtgtaattct agtatggttg
    59281 ttgatagtat agaccaagta aattatcaga cttttttaga tagagtaact tcttcatgcg
    59341 tagtagtaca aaatgcaatg gaacctgtta tgaaaaactt ttcttttaga atagatagaa
    59401 gtgtagctga tatgtggatt gatataactt ctggaggaac tggagttgta aaggataatg
    59461 atagagagct tacagaactt gataaaaaag tgcttttaca ccttatggat gatttagtaa
    59521 gaaatatgca cttatttgag ggttttgaaa atatacaagt attggataca catacacata
    59581 ttaatttgcc acaattatgt tctccaactg caccagtatg cgttgtagat ttaaaagtgc
    59641 taaatgataa tgagtgtatt ggaagtgttt ctctttgttt tccatacaat ggtttagagg
    59701 ctctgttaga aagtatatct gttatagaat tttttgataa tgatgtagga gatgattcag
    59761 aggaatttac ccaaaaaatc tataatagtg tatctaatat agaattatca gttattgcag
    59821 agataggaaa agtatcaatt aatgttgagg atttacttaa actagaagtt ggagatgtaa
    59881 tagtaacaaa taaaaaaata aatgattata tagatatatt tgtagaaaat tcaaaatcat
    59941 acacagcaac accaggattt atatcaagta aaaaaggtgt aaaaataaat gatgctgttg
    60001 gaaaagaggt gtagttatgg acaatagtaa tcttatttca gatgaagaag caaagatgtt
    60061 attaaatgat aaagttgaaa gtgaagttga tggagatgat gagttagcct tagatgtctc
    60121 tgaagttaat cgaaataata tacaaaggat acttgacctt aagttagaat tatctgtagt
    60181 tataggaaga actaagatga ctctaagaga tattttaaat ttacataaag gttctcttat
    60241 tgaactggat actttagcag accaagatgt ggaaatacta atagataata aggttttggc
    60301 ttatggaaaa gtagtggtgg tagatttaaa ttttggtgta aagataacaa gtatagtaag
    60361 tgaagaagac atggtaaaat ctcttgttta gagataacat caattaatac ttaaggcatg
    60421 aggtggtact tattttaaac ttaaatgata taaaaaaaga tatactaaaa ctcaataaaa
    60481 aagactcatg ttctctatat aatgaatcta ttaataatat aaataataat tgtatatcaa
    60541 ctggattaaa atttttaaaa caagcaagag atttaaaccc agatgatgtt gatatattaa
    60601 atctcacagg tcttgtaaac ttactaaaat gtaattttga tgatgctgta gaaagtttct
    60661 ataagagttc actttgtgaa aaaactgctc tgtgtgaaaa gtatataaac atgcttacat
    60721 ctgaggagtt tttaattttc tttgaaaagt acaatcaact tataaggtta ataaataaag
    60781 gaatgtataa agaagctata caagggttta aactcataac tgaccaatac tgtgatttaa
    60841 tagaacctta tgagttgctt gccttactgt atgacaagga agaagaatat ataaaatttg
    60901 atgaatgttt agaagtattg aagattattg ataaggaaaa ttatttatta aatcaagaaa
    60961 ataacacatt agatatgtat aatagtgcta atatacaaac taaaagtaat ataaaagtag
    61021 atgattataa gaatgagttc ttacataaaa gtagtagtaa ccataaaatt aatgattata
    61081 atgatgtaac taaagaaaag agttcaagca aaaaccagaa aagttcagat tctaataaga
    61141 aaaaaagtat taaaaaaaat aagtacctat atatagccat aatattagga atattattag
    61201 taggacaaag tatatataat tcttataaga tgaataattt aactgataaa atatctaaaa
    61261 ataatgaaac taaaaatgaa gagtcaatag attctaactt gactaagaaa gaaaataata
    61321 tagaagaaaa tgaagatatg agtaaggctt ctaatataaa taagagtaat aaaaacatta
    61381 ataaagagga tgatgtaaaa tctaaaaaaa atactgtaga aaatgaagat gataaagatt
    61441 ctgacttatt tacagaggat gaattgatgt ctaaggcgaa tactttaaaa tcagaaaaga
    61501 aaactaaatc ttctatacaa ctatataaga aagttgcaga tataggtgaa aataaaggga
    61561 atacatctga agcaacttat caagttgcta ttctcagtga aaagttaaaa gactataaaa
    61621 ctgctgaaga atattataaa atgtatgtag aaaattactc agaaaaagat gcttattttg
    61681 atgaatctta ttataattta ggtatgatgt actataacaa tggtgattta aaaaattcta
    61741 aattgacatt aaagaagttg gttaataagg taccaaatag tatgtataat aattcaaaag
    61801 taaaagaaat tttaaaagaa gaatagttaa attagataag aaaaataaat tattttattt
    61861 taaaataata tgattataat atattgacat accattttaa aaaatttaaa atattaatta
    61921 taaaatgagg agggataaaa aatggaattt gaaaaaggga gtatttcaat tcatacagaa
    61981 aatatttttc ctataattaa aaaatggtta tactctgata aagacatatt tataagagag
    62041 cttataagta atggatgtga tgcagtaagt aaacataaaa gacttgtatc actaggagaa
    62101 atatcagaaa ataagtcatc agattataaa attacagtat ctgtaaataa aggagaaggt
    62161 acacttaaat ttattgacaa tggaattggt atgactgaag aagagataaa aaaatacata
    62221 aatcaagttg ctttttcagg tgctgaagat ttctttaata aatataagga taaaatggaa
    62281 gagtcaaatg atataatagg tcattttgga ttaggatttt attctgcatt tatggtgtct
    62341 aaaaaggtac aaatagatac actttcatat acagaaggag cgactcctgt aagatggata
    62401 tctgaaggtg gtacagaata cgaaatatct gaatcagatg ctagaaatga tagaggaact
    62461 actataacac tatttattga tgatgatagt aaagaatttt tagatgaatt tactgtaaga
    62521 ggaataataa ataaatactg ttctttctta ccagtagaaa tatatttaga agatgttgaa
    62581 agattagaaa gagaagctaa agaagcagaa gaaaaagcta aaaaacaaaa ggaagatgga
    62641 aaagaagaga ttgtagatgc aaaagtaatt gagcctttaa acgacactaa tcctctatgg
    62701 ttaaaatctc caaaagactg tactgatgag gagtataaag agttttatag aaaggtattc
    62761 aatgtatttg atgaaccttt attttggata catttaaatg tagattatcc tttcaattta
    62821 aagggtatac tttacttccc taaattaaaa aatgagtttg aactgactga aggaaaagta
    62881 aaattataca acaatcaagt gtttgtggct gacaatataa aagaagttat accagaattt
    62941 ttacttttat taaaaggagt tatagactgc ccagacttac cattaaatgt atcaagaagt
    63001 ttcttacaaa atgacaggga tgtaagcaaa atttctaaac atataattaa aaaagtagct
    63061 gataagttaa aatctctttg taaaaatgaa agagaagaat acaataagtt ttgggatgat
    63121 atacaaatat ttattaaata tggttgctta aaagatgaaa gtttctatga gaaggtaaaa
    63181 gaatgtatat tattcaaaac tattgatgat gagtatataa cattacaaga ttatttagaa
    63241 aagtgtaagg acaaacatga aaataaggta ttttatgtaa gtgataaaga acagcaatct
    63301 caatacatta aactatttaa agaatacgac ttaagtgctg ttgttttaaa ctcatcaata
    63361 gatactcatt ttatttcatt tatggaatat aaagagaatg gagttaagtt taatagaata
    63421 gatgcagacc tttctgatgt attaaaagat aaaaatgaaa ataaagatag tgaagaaaac
    63481 aaagaagaga tagctaagat agaaggtctg tttaaagaag ctgttggaga aagagtgaag
    63541 aattattctg tagaaggatt gaaaaatgaa gacactccag ctatggtgtt agtatcagaa
    63601 caatctatta gaatggcaga aatgcagtca agatttgctg gaatggattt aggaatgaat
    63661 tttgaagaag aaaaaactct tgtaataaat gagaacagtc caataatcaa aaaattggtt
    63721 tctcttaaag atgatgagga aaagaaagat aagattacgc ttatttgtaa ccagatagca
    63781 gatttagctt tactttctaa taaagaatta aagccagatg agttagattc atttgtacaa
    63841 agaagtaata agcttatgag tcttttgata gaattataag attgaatttg aatacattga
    63901 agcaaattta taaaaagtat tcaatatcag tgataagaaa gaagtgtctc aaaatgaact
    63961 tttcagttca tgaggcgctt tttttatgtg aaattaaatt tattttaatc atttcaacaa
    64021 tgaaaaatat atttatctct attttgagac agaccgttct ttattttttt atctttggtt
    64081 aatttttaaa tatttaagta ggttctaata aaaaactcta tttagttaaa tatagttaac
    64141 ttgatatata ataagataat acatataatt aagtaaaaga ttgtttttta gtttatgttt
    64201 aaatacataa ttacactttg ttaaaaacat aaaattatta ctaaagtaga aataggaggt
    64261 tttagcatga attttaatta taatttgcca gtaaatatct tatttgggag cggcagaatt
    64321 aatgatgtgg gaaaagaagt atctaaatat ggcaaaaaag tattgatagt aacaggtaaa
    64381 aatagtacaa agaaaactgg attacttgat aaaacaatag atttactaaa agactctaaa
    64441 atagaatatg aagtttttga tagagtagaa caaaatcctc ttataactac tatatattca
    64501 ggagtagaaa ttataaaatc aactggatgt gattgtgttt taggtcttgg tggtggaagc
    64561 attatggatg ctgccaagag tatagctttt tcttataaaa acccaggaga tttaaatgat
    64621 tatatatttg gaattagaca aggtgaagaa gctttaccta taatcttagt tccaacaaca
    64681 tcaggtacag gtagtgaagg aaattgtttt gcagtactta caaattcaga aactaaagat
    64741 aaaaaatcta taaagaagaa tagtatgtat gcaaaagcat caataattga cccagaactt
    64801 atggttacaa tgccaaaaca tataattgca tcagttggat ttgatgcact tgcccataat
    64861 atggaagcat atctttctaa tggaagaaac cctcttgcag atgtacaagc tatttatggg
    64921 attgaactta tatcagaaaa cctaataaag gtatataatg atgttaatga tttagaagca
    64981 tgggaaaaaa taacacttgc aagtactatt ggaggaatga cgattggtac agcgggtaca
    65041 gccttgccac atggaatgga gcatcctgta agtggtctta gagatgtaat gcatggaaaa
    65101 ggacttgcag ctttgactcc tactattata gaaagttcat gggatagtga tattgaaaga
    65161 tttggtaata tttcaaaggt attaggagga acttgtgcag aagattgttc agatgcaatt
    65221 agaaatttcc ttaaaaaaat agatttagat ataaagctaa gtgatttagg tattaaaaaa
    65281 tcagatatag attggttaac tgataattgt atgaaaatat cagttgcaaa tattaagaga
    65341 catccaaagt attttaataa ggaacaaata aaggaaatgt accataagtc tttataattt
    65401 gactttacat atttagtttt atataaaaat tataaattaa taataaaaaa ttataagtaa
    65461 ttaatagtaa aaaaattgtg tatagaagtt atatatataa taaatttgtc ttaagctttt
    65521 attttacttt ctaataaata aaggagttta aaaaagggaa gattaattaa gtaatatttt
    65581 ataaaattct tcgatttaaa aactttaagt agaggtgaaa taaatgttta atcccaaaag
    65641 aataatattc gaaaaaggaa ctttagacac tgatgtgggt aaaaaaatat acaataaatt
    65701 tagagataat aaagatgtag agataattaa tatatcatca aataggatta aagaacatat
    65761 tccaggtgaa aatctatatg aacaatatag aagtgggaag cagactatgg tagttgggat
    65821 tagaaaaagt ctgaagtttc aaacatgtaa accttctgct aattatcaac taccacttgt
    65881 cagtggatgt atgggaagat gtgagtattg ttatttgaac acacaattag gtgataaacc
    65941 atttataagg gtgtttgtaa atgtagatga aatacttgaa cagacaaaaa aatatattga
    66001 agatagaaag ccacaggtaa ccatatttga aggggcagct acatcagacc cagttccagt
    66061 agagccatat actaattctt tgaagaaaac aatagagttt tttggaagag aggaaaaagg
    66121 aagatttaga tttgttacta aatacagtga tgtggatagc ttattggatg ctgaacataa
    66181 taatcataca gaaatacgat ttagtatcaa tactcctaga attataaatg aacatgagca
    66241 ttatacagcc tctgcaaata aaagaataga gtcagctgta aaacttgcta gggctggtta
    66301 tcagattggt ttcataatag cacctgtgtt tttatatgaa ggttggaaag aagagtataa
    66361 aaatctgatt ataagtataa aagaagcttt accaaaggat tttgataaaa aaattatatt
    66421 tgaagttata tctcatagat atacaactaa agcaaaaaat agaatactag agatttatcc
    66481 agatacacta ttgccaatgg aaaatgaaga tagaaagttt aaatacggtc aatttggata
    66541 tggtaagtac gtgtatgata aagaacaatt agatgatatg aaagagttct ttcttaagga
    66601 aataaatgga gtatttaaaa atagtttaat aaaatatata atatagcaaa tcttacctaa
    66661 agatttgcta tattttattt ttatatattt tatgtttata ataaagcaat gagatttagc
    66721 attatcatat aagaaaatta aaaagggcac tatctatcaa gaacattttt tctagttttg
    66781 atactataaa ggataagagt aacaaaaata tcaggaggag ttatagtatg catgcatggg
    66841 agtctattca aattacattg gatttaatag aagcaaattt atcagaagaa atatcaatta
    66901 atgaattagc aaataaagca aatttatcac cattttacta tcaaagacta tttaaaagat
    66961 tggtaaataa gactgtaatg gagtatataa agcttcgtcg tcttgcaaga gcttctgaat
    67021 acttagcaga acataagaat cgtatacttg atgtagcttt aaattttgga tttgctagtc
    67081 atgagacatt tacacgttcc tttaaaaaag catatggatt aactccagaa aaatatagag
    67141 caaatccagt aaaactcaat cattttatta agccagaatt aattttaaat tatgctatgg
    67201 ttgatgaagg tgttccactg attgcagatg atatagtgat tgaagtcaat cgtaagacat
    67261 tgagtaatcc aaggacattt gttggaatag aaatagaagt acctatttgc cagttggtgg
    67321 gcggtgaaac aactggaatt gcaatagtag aggaattatg gatgaaactt ggaagtcaaa
    67381 gacataatat accaaatcaa attccaggtg gaaatgaatt tgctgctctt tatatgggaa
    67441 atgcaaaaga aggaaattgt atgtatatgg caggtgtaga ggtagagtca ggtacatcag
    67501 tagaaggata tagtactttt gagttgccag ctaaagaata tttagtatgt ggatttgagg
    67561 cagaaaactt taatgagtta gttaattcag ctgtttttaa agcagataaa tttatggaaa
    67621 gatggatgaa gaaacataat ttaacaacta ctgattttgc aattgagatg tattacccca
    67681 ctacacctga agcagcatat ctggaacatt ggattgttcc ggttcctatt gaacaataga
    67741 aaggatgatg aatatgaatt ggcaagatgc gttttttcaa gatactaaac ctacatttga
    67801 gcaaattaat gaatttatta ataatccatt atgggacaag ttaaataaaa ctttggtttc
    67861 tacttataat gtagaaccta agcttgaata cagtaaatgt tcaatgcaaa gaggttggaa
    67921 tgtaaaatat aaaaaaagag gtaaatcact atgtacttta tatccacaag aaggttattt
    67981 taaagctttg gttattgtaa gtgaaagcaa tagagtagag gttgatttat ttattaatac
    68041 ttgttgtgat tatatcaaaa aaatatataa tgaggtaaac ttttttaatg gaagtaaatg
    68101 gctaatgatt caagtagata gtttattggt attaaacgat atgcttgaac taattaaatt
    68161 tagagcttaa catatagaac aggatgaata tataagtcat cctgttttta tattcaatca
    68221 gataaattaa tatatagtct ataatatgaa taatttagta aatttaaatt tactttatct
    68281 ttctacattc tttgcaacta agtccacatg tgtttttttc ttgcatatta gtagcacccc
    68341 aattagcaaa ttgttgtaaa ataggcacaa tacttttacc tttacttgtt aatgtatatt
    68401 caacttttgg aggaatttca ttatattgtt tacgatgaac aataccagta gactctaaat
    68461 cttttaatga ttgagctagc atagtatttg taatgccatc caattttctt tttatgctac
    68521 tatatctaat tggattttca actgctaaca tacatataat aggtaatttc cacttaccac
    68581 cgacaatgtc taatgcataa cggattggac aggttaattc ttcaacgttt ttagttatat
    68641 ttttttcagt atttatactc attttaatta ctccttagtt atagtagtat cttttttata
    68701 ctttatcaga aaaaactgca tacttgtttt ttctgtattt tatattaaaa ttatatcaaa
    68761 ggataatcct taatacaagt atttaaaagg ggtgtaagaa ttatgaaagc attagaattt
    68821 ttgaacaagg caggagttta ttatttagca acagttgatg agaacaatca agcacatgtg
    68881 cgtcctttag gatttgttat ggaatacaat ggtaaactta cattttgcac atctaatcaa
    68941 aaggatatgt ttaagcaact tatttttaat ccaaaggttg aactttgttg tatagaccaa
    69001 aaccttaata ctctacgtat tttaggtgaa gcagtatttg ttacatcaaa agaaacacaa
    69061 gctaaggcac ttgaaataat gccaagttta ggtcagatgt actctgtagg agatggtaag
    69121 tttgaaatat tctctattga taaggcaaaa gttagttgtt gttcaatgag tggtaaaaag
    69181 attgatgtag agctttaatt ataattgaat cgacatccat agcgaaaatt aagaaaacgt
    69241 tattactgaa atattgatag atttaattta aatgcaataa aaagattttt aactaatgaa
    69301 tatgtaaaaa tttttagtta ttagatgtgt atttcaataa tgatatacta ttttgaataa
    69361 ttacatacta gaaataagat aattaaaatt tactttataa tgggatagat ttcttttaaa
    69421 aaatatttta actataattg atttttattt aatctgaaaa aaatattatg actataaaaa
    69481 attgctactt attatttgga tatttttata tataaataat aagtagcatg actttataca
    69541 ttaataatga tagaatataa attaatagat aagatatgat tttaaaagga gtgatataag
    69601 atgagtaaat atagttcttt atgggaatat gttaagaaaa acaatagtca atcgtttaaa
    69661 ttaacttttg aagaaataaa agatattgct gggatagaga tagaccattc gtttttgaaa
    69721 tataaaaagg aattaaatga atatggatat caagtaggaa aaatctcttt aaaagagaag
    69781 actgttattt tcgataaaat tggttaagac ataaataatt acatataata aaataatttg
    69841 tattgatgat tattacaaat aaaaataaag taaaccttat ataagattta ctttatttta
    69901 gatgattctt ttttttagct ttatactata aggtatataa aactaagctt attaaaaatg
    69961 ttataatttc tattgctatc atagaccata tcaatccatc aagttcataa aagtaattaa
    70021 gctttattaa atagcttctt tattataatt tctttatttc atataatata aatagtatta
    70081 aaatttttat gggagttaaa gtaagcatgt attattactt agatatttgt ataatcaaca
    70141 tctagtaatt tacctttttg atgaaaatga ttaataagtt ttttaggata attcattatt
    70201 aattcatctg gaaaattaat ttcctttaag atattttcag aatactcata gttacctatg
    70261 tcaaaacaaa tgtgagcatc tgaagttagt atgattttag caccatattt tttgcaaagt
    70321 gtagcaatat acttacagtt atccgagcta ccatttcttg acacgccttt aatagaacaa
    70381 ttatttattt ctattaagat attcttttct atagctaatt taatgattaa ttcatagtcg
    70441 attgggtagt ttgggtttcc aaggtgtcct aatatttcaa tattatcatg cttatttatt
    70501 gcatttatta aagctttagt attattctct aatgtatttg gagaaaacac agcttcgtga
    70561 aatgacaaga taagataatc taaccgagga attacaaaag gctctaggtc tatgtttcct
    70621 ttaatatcta gtatatttgc ttcacagcct cttaaaatta taatgttatt tatgattctt
    70681 gggatatttt gaatgttgtg aaagtaccat ctgtggggag aaccaggcat cttaggacca
    70741 tgttcagatg tacctagtat cttaattcca ttttctttac aataattaat attttctagt
    70801 aaagtgctat agccatgacc actgactata gagtgggtgt gtaaatctga taaaaaattc
    70861 atataaattc ctcctctata aaagatgagg gtaacgtaat ttatattata aaacgaatag
    70921 gaaagaaaat caatagttac ataattagac aaaaatatta aaatattgta gaattaagct
    70981 taataataaa tgtttaacag tattactgct tataggggag gttaactatg acacaaaaga
    71041 agctatcaag gaaagaaaaa gttttaattt gcttgaaaag gttaacagaa gaacacttga
    71101 actttaataa tggcattaga tttggatttg atgcagaata tatagctact gaagtaggta
    71161 taaatagaag taatgctagt aaggaattaa atcaattaat aaaagaaagt atcattataa
    71221 agataaaggg taagcctgtt cagtacttat ataaagaaag tattgagagt attttaggaa
    71281 agaaactaaa taaagggata tttgataata ttaactctat aaacgaatat agtgaaaatg
    71341 attctatcaa agatgagtat attttagaga gtataaaaaa agagaacaat atttttaatt
    71401 tagtaggatg tgatggaagt ttaagatccc aaatagaaca ggctaaagca gcagtaatat
    71461 atccacctaa ggggttgagt acattaataa taggacctac aggagttggt aaatctatat
    71521 ttgcagaata tatgtataag tatagtttaa ctataaaaga agatagtgat aatgcaccat
    71581 ttatcatatt taactgtgct gattattctg ataatcagca attattatta gcgcagcttt
    71641 ttggatatgt aaaaggagca tttactggag ctgataaaga taagtatggt attgtacatg
    71701 aagctaataa tggagtattg tttttagatg aagttcatag attatctgca gagggacaag
    71761 aaatgctatt tctgcttatg gataaaggga tatatagaag gttaggagag gctaataagg
    71821 tacacgagtg tagagttatg ataattgcag ccactacaga agacccagaa acagcaatgt
    71881 tggaaacgtt tttaagaaga atacctgtaa ctataaagat tccgtcttta gaggaaagag
    71941 gctttcaaga gagaatgaag cttatatgtt atttttttaa agaagagagt gttaggattg
    72001 gtgttaagtt aaaggtttca aaagaagtta ttaaggcatt tattttatat aagtgtaagg
    72061 gaaacatagg ccaattaaaa agcgatatac aattaatttg tgcaagagct tttttagatt
    72121 atatgaccta taaaagggaa tgtgtatatg taaggctctc tcttctacca aataatatta
    72181 gagaatcatt atatggaaat aatagaaaag aggagtttgt acaaaatttc agttttattg
    72241 gaaaagatga tattattttt ttaccagaag aaaaggattt tgaaagtgaa aatttattaa
    72301 tagaaaataa aaaatatgat ttagattttt atggaatgat aaaagaaact tggaataaac
    72361 ttcaacaaga aggtattaaa gagtcacaaa ttagaagtgt tatagatgga gacatacaga
    72421 agtattccta taatttaatg aatactttta tatataatag tagtaatcaa acagcttata
    72481 acaacattgt taatgattca attgcaacta ctgtaaaata tattttacaa aagcatgata
    72541 aatggagcaa aagagaagga ttagataaat taataaaagc tatagcttta catattcaga
    72601 atttaattga aagaataaag attggaaata tagtaaagca tcctaataaa gatgaaatta
    72661 tgaaggaaag agcatatgaa tataacatag caaaagaaat attatctaac atgtcattaa
    72721 tgtatggagt agagtttcca gaagatgaag caattttttt agcaacattt ctttatttat
    72781 cgtatgtggg attaaatgag gagagtatag caatattagt cataatgcat ggtgaatcta
    72841 cagcatctag catggtgaat gtagccaata ctttactgga ttgtaaccat gcagtggcaa
    72901 ttaatatggg attagaagat agagttcagg atattttagt acaagctgta gaaatagcca
    72961 ataaaattga taaaggaaag ggaattttaa ttttaactga tatggggtct attttaacat
    73021 ttgctaaagt tattcgtgat gctacaggaa aagaagtaaa agcaatagat atggtaagta
    73081 cacctattgt aatagaagca actagaaagg ctctaactcc agaaatgaca ttagagaaat
    73141 tatattttaa tattatagaa tctataaaga aacattatgg agatatggaa gttacatatg
    73201 ctgaaaaaga taatggtggt agatattttg atagattact aattgataat attagtaaaa
    73261 ctttgacttt tttaaatggg gaaaaggctt attttatatt aaaagaagta attaatagaa
    73321 ttagtgaaca ctattcttta gtaattcaag atgaactttt agtaaagttt atatttcatt
    73381 gttcatgtat gattgaaaga gtaataataa aagagtcttt agtttataaa tcatatgaag
    73441 aaagaattag tagaaataaa gaattatatt tagttataaa agaaagtttt aagctagtag
    73501 aagagacatt cgatataatt atttcagata tggaatatgc aaatatatta gatatatttg
    73561 aatcacaata tgatacagat aaattcaaaa gttgatacaa aatttaaaaa tagccaaaag
    73621 gctatctttt ttttactttt tttgatacag atttgataca ggttgaaaaa atcttttgat
    73681 acatatcgaa ataataagtt tttaaaaaaa attgaataaa aagttttgat taaatcctgt
    73741 aaaatagcca tttgttattg atacacataa gttggcacgg caattgctta tataaaaagt
    73801 gacaagaaaa gtgaggtgaa attggtgata ggaataatag ttatgactca tgggagtttt
    73861 agtgaagaaa ttataaaaag ctgtgaactt attgcaggac cagcagaaag aacagcagca
    73921 attaaactaa ataggaatga taatattgaa gacttaaata aaaattttgt agaaaagtta
    73981 aatgaattag atgaaggtga cggagtttta gtattagctg acctattagg aggttcgcca
    74041 agtaatgttg caagtttaaa ccttaaaaaa ggtggcaagt ttcatgcact tactggagta
    74101 aatcttccaa tgctacttga agctttaatt aatagagagg gaaaaagttt agaagagtta
    74161 gcagaagcat gtattgaagc aggacaaact ggtataaaca atattaacaa agttcttagc
    74221 tcaatgtaat agaaaaagga gtttgattaa aaatgtcttt agtaaaatat tgcagatgtg
    74281 atgatagatt aatacatggt caagttatat ataaatgggt taagcatcta ggtgtaaaaa
    74341 agatagtagt agtagatgat gaaacaacca atgatgttat tgctaaaggt ttgataaaaa
    74401 tggcagcacc aaagaatatt gatttatcaa tattaactgt aagtgaatca aggagatatt
    74461 tttataataa tcaagctgat gataacgttt ttgtattaat taaaaattta gatactgcaa
    74521 atagaatgat agaagaaggg attaatatca aaaaacttat tgttggaaga atacctacag
    74581 gaataggaaa aaagaaaata tctcaaaatg tatacattaa taaaaaagag tttcttttaa
    74641 tagatgaatt tattaaaaag aatattaatg tatcaattca aatggtacct gatgaagaag
    74701 aagtagaatt aaaccaaaat attaatcgct ataaaggaga gtttatttag caatgaataa
    74761 atataaggta atcatactgt gccatggaac ttggggaaaa gtcttagtag aagaaacaaa
    74821 taaaaacttt ggattgtcaa atcaatatga agttttatca ctaagttctg aaaaagatgt
    74881 ttctgtattt atgaaagagg ttgaagaagt agtagataaa gaagatgtga aaattataat
    74941 atcagattta tatggaggat ctacatcaag tgttgcaata gctgttgcta taagaagagg
    75001 aatagatgca ataaatggac ttagcttaca gacaatttta atcgtagatg aagaattaag
    75061 caaagaagat aaattacata cattaccaga aagaatcgtc aaaaaaaata ataacctttg
    75121 tgtggattta attaaagaat ttaaaaaaat ataaattatg aggtgaatat aatggcaaaa
    75181 ataacattag taagagtaga ccacagatta attcatgggc aagttataac aaaatgggta
    75241 aaaatcgctc aagctcaaaa aataataata gttgatgact tcttaggtca agatgaattt
    75301 atggctgaca tatataaaat ggcagcacca tcaggagtag aagtagttat tttaacagca
    75361 gaagatgcgg gacaagcatt ccaaaacaac actttaggag ataaaaatat atttattcta
    75421 tttaaaaatg ttgatatggc aaataaggct tataaagctg gacttaaata tgaaaagatt
    75481 caattaggag gtattccaaa tgaagcagga aagaaaatgg tgtttacagc tgtttcatta
    75541 ggaaatgagg atgtagaaca acttaatgaa cttaatgaaa atggggttga aatagtccta
    75601 caagttatac cagaggaatc atctatgaca tatgaaaatg cgttaaagaa atttaaataa
    75661 aaaatataaa ttaggaggaa ttataaatgg aatctgtttt gatgttggca attgtaacag
    75721 gattatggta ttggtttgca gcaggtcttg cagggtatac ccttttctca acactaaagt
    75781 ctcctttatt tataggtttt agccttggat tactttgggg tgatgtaaca actggtatga
    75841 ttgttggtgc aagtatagaa atggtttatc taggaatggt cgcagcaggg ggaaatattc
    75901 catcagataa atgtctagct gctcttattg caataccagt agcacttcaa actggtgtta
    75961 atgcagaagt tgcagtatct attgcggtac ctttaggtgt tataggagta ttagttaata
    76021 acttaagaag aactggtaat gctgtattgg ttcataaggc agataagtat gctgaagaag
    76081 gtaatacaaa aggcatctgg agatgtgcaa cactttattc tttaatattt gggtttgttt
    76141 taaggtttcc aatagttttt gtatgtaact tttttggagc agatttagtt caatcattat
    76201 tagatgttat accacaatgg ttaatgaatg gattaacagt aatgggcggt atattacctg
    76261 cattaggttt tgcaacaaca atatttacta taggtaaaaa taaattttta ccaatgttta
    76321 ttataggatt ttttatggtt caatattttg aaatatcaat tactgcagct gcaatatttg
    76381 gtgtttgtat agctctttta attaccttta tgaaagaaga caaaagggta ggtgaagtat
    76441 aatgcaagaa ataaaaaata aagaagttaa aaatggacaa ggtccaactg aagttaataa
    76501 gacaagagta cttacaaaga aagatgtaac aaaaacatat ctaagatggt ggtggacagc
    76561 agaattatcc aactcttttg aaagaatgca agcattagca gtttgtgcaa gtttcactcc
    76621 ggctttagaa aagttatata agagaaaaga agatttagta gatgcgttaa agagacactt
    76681 acaatttttt aatactcaag ctatatgggg aggattaatt cacggtacag ttttagctat
    76741 ggaagaagag aaagctactg aaggaaaaat cccaggagaa gttatttcag gtgttaagaa
    76801 tggtcttatg ggacctttgg ctggaattgg agatacttta gattttggta catttcaaac
    76861 aatattctta gctttaggtg cttcatttgg agcagaagga agtgttatag gtgcattttt
    76921 cccaataatg tttagtatat tactattttg cgaaggttat tacttatttc atttaggata
    76981 ttctttaggt agagattcaa ttaagaaaat tctatcaggt ggtattgtca ataagataat
    77041 tgatggtgct tcaattctag gaatgtttat gatgggagca ttatctgcaa ctacagttaa
    77101 gctttcaact ccgctatcat ttgatattgg tggtaaagca attgttgttc aagatacatt
    77161 aaatatgatt gctccaggtt tattaccact tggtgttgta ttcttcgtat attggggaat
    77221 gaaatacaag aagtggacaa taactaagtt attagtaatt ttagttgtat tagcattggt
    77281 agggtcattc attggaatat tctaattcac agtgattaaa atatagaatt taattttagg
    77341 aggagaaaga aatgtcagaa aaaatgtata cagaaaagga atatttagaa ggaattagag
    77401 gagcaacagg agaaagagca gtatggttct atcttcttat gaaagaagct gaaaaattag
    77461 gagctaatcc agatgatata tgtaaagaag caatatatgg atttggtaaa atgagaggtc
    77521 aaaaatataa cgtagcagat actccaggaa aaatggcaga aatgttatat aacagtaaag
    77581 gacaaaaagt gtttgaaatg gaattagtag aaaatacaga tgagaatggc gttttaaaat
    77641 tccatcactg tccattagat gctgcttgga aagaatatgg attaactaaa gaagaaagaa
    77701 aagaaatttg tagattagct tgttatgggg attatggaag agttgactgc gcacaaggtg
    77761 ttaaattaga ttttgctcaa aaatgtgctc atgatgatga agtttgtgaa ttagtattta
    77821 caaaaaaata atttttaatg ctaaaagcct gttctttaag gacaggcttt aaaaagatag
    77881 aaagtaggtt gatttatgga tataagcaga agtgtagata atagtttaaa tagaaccata
    77941 gaatttctaa aagaattgat aaaaattgat tcacaacaag gtgaacctat ttcacaatgt
    78001 ccttttggta taggacctaa aaaatcttta gataaaactt tagattactg tgctagttta
    78061 ggttttagtg ttaaaaatat tgataattat attggatatg cagaaattgg agagggagag
    78121 gaattaatag ggattccaat gcatttagat atagttccac caggagaggg gtggagtgta
    78181 gacccatttt cgggagcagt aattgacaat attatttatg gaagaggtgt aatagataat
    78241 aagggtgctg tatctatgct tatacatgta ttgaaaaaca tagaggatat gtatcctaca
    78301 attaataaaa gaataagatt aatttttggt acaaatgagg agacaggtat gaaatgtatc
    78361 aaatattact tagataaagg tgaagaaatt ccaagtatgg gatttactcc agatgctatg
    78421 tatccagtgg ttaatggaga aaaaggaagg gttcatataa ggatagaaaa agaaattaaa
    78481 attgacaaaa gtaaacctta cataatagta aggggaggaa ctaaagaaaa tgttgttcca
    78541 tctcattgta ctgcaaaaat tattaatgga attatttcag agttaactac taaaggagta
    78601 gctgtacatg caagtaatcc tgaaaaggga gaaaatgcta tatctaaaat ggtaataaag
    78661 atagttgagg ataatatgga ttttcagcat agagaagata tcgaattagt ttcaaaatac
    78721 ctttgtagtg attattatgg agatgcatta gggattaatc aatatgatga ggtattcaaa
    78781 aacactacct taaatttagg aatattaaaa gtaaatgagg aaaaaatcgt atgtgagtta
    78841 gatataaggt atggtaaaaa tatagtttta aacaatataa tagatagatt caaaaaggtt
    78901 ttttgtaatg gttggaaaat agaggttatt gctcataaag acttacatta tgtggatgag
    78961 agtaatttag tacttaaaaa attattagaa gcctatgaag aagtaacaga tgaaaatgga
    79021 tatacaattg ctatgggtgg tggcacatat gcaagttggt ttaaagatat ggtggcgttt
    79081 ggacctaagt tcttagcgta taaaactggt ggtcatggag tagatgaaag agtaccaata
    79141 aatcatatac gaaagaatat ggagatatat actttggctt taataaaact attagaattg
    79201 taaaagaaga agagacttta tgtgcaaatt tacagatatc ttaaaaagag agataaaacg
    79261 agttcaacct tatttaaatg ttcaacacca tcaaatgggg ctgtctcaaa atagagataa
    79321 gcctcttact tattgttgaa atgatgaaaa tatattttac ttcatacaaa aaagagtgcc
    79381 ttatgaagta aaaagttaat tttgagacac cctcatttga tgatgttgaa gagaaaataa
    79441 gtatgaaatt attaaaaaag atgattttat aaaagttaag gttgaaaaga aaagttaatt
    79501 gaatggaatt agataaatgg agaaggatgt atactatcta ataaaataac aaaagagtgt
    79561 tataaagttg gttatatgat tagagaaaag tctattgata cttatccaga tagtggatgg
    79621 ggatttatga cttgggatga aaatggagaa taataaaaat tatagtttat acagtttaat
    79681 aagatatatg tacaagcagt taatctaaat gattgactgc ttttctttta tagattttta
    79741 tataatagac aaataccaat acatgatagt tgcctgttat aattagagaa ataaatacga
    79801 ataataactt tataaaagaa ttaaatggaa aatcgaagag ttatattcag tattttaaaa
    79861 agaatatgaa atgagaaatg aaaataaggt gtttatatta aaagaggttt tacacaaaat
    79921 atttaaaaac gtgataaata aaaactgtat ttagatagat taactattag ttttatataa
    79981 tatggatttt atttacaaag tttacatatt ttacaaaaga gattaaagat aaatttaaat
    80041 atatatttta tatacttgtt tatttgtttc tctgtggttg attttttcgt caaaagtcaa
    80101 cttcaaatcg cttgttagct ttacatgttt aaggatataa ttatacataa ggagggattg
    80161 acatgaatga attaaacatc gcaaaaacgc tgattttaaa gcgtaaagaa aaaggaatta
    80221 cacaagatga acttgcaaat tatataggcg tttctaaagc ttctgtatct aaatgggaaa
    80281 ctggacaaag ctatcctgac ataacttttt taccgcaact cgcgacatat ttcaacatta
    80341 ccgttgatga gttaatatgt tatgaacctc aaatgatgaa ggaagatatt aataaactgt
    80401 ataataaact gtgcaaagac tttacggtta aaccatttga tgaagtcatg gatgaaataa
    80461 gagaaatcat aaaaaaatat tattcatgtt ttcctttgat ttttcggatg ggtcttttaa
    80521 tagttaatca ctatgatatt gtagatgaaa aaaagcgtga actattaatt agtgaagcat
    80581 tagaaatatt tattcgtata caggaaactt gtaatgacat agatatttgc cgtcaagcaa
    80641 aaagtatgga ggcaacttgt tatatattgt taaatcaacc catacaagtg attgatttat
    80701 tgcaaaacag caattttccc atgataaatg aatctatact tcttgcacag gggcaaatga
    80761 tgaatggtca aatggatgaa gcgagagaaa catttcaact tggtgcatat cagaacctta
    80821 tatcattagt ccaaaaccta gtgggtattt tgcaaaatgc agataaatta caaatgaagg
    80881 aaatagaaag acgtattcta gcaatttcag atatatttga gcttgataca ttatctcctg
    80941 ctattatgct ttcttcatat ttaacacagg cacaaattaa tttaatacat ggtgataatg
    81001 aaggagctat taaatcatta cgaaaatatg tagatttagc aacacgtgat atatacccaa
    81061 ttataataca tggggatgac ttttttaata aacttgacag atggatttct gaaattggaa
    81121 caggtattac acgtgatgat acaatcgtaa aagcaggtat tgttgctgct attaaaaata
    81181 atccaatgtt ttctgtatta agtgaaaaca aagaatacaa atttcttata gaaaaattat
    81241 ctttattgga ggaataagat tatggaaaat ttgatggaat acttaccact tttggttcct
    81301 gttattattt tagatttaat acttataatt actgcacttg ttcatgtatt gagacatcca
    81361 aattataaaa ttggaaataa ggcaatatgg attattgtag tactgtttat tagtctaata
    81421 ggaccaattt tgtattttac aataggaaga ggtgaagaat gatgaatatt gtctcaataa
    81481 atggattatc aaaaggtttt ggtaatcgaa agataataga taatttaaat tttactgtac
    81541 cagaagggtc agtctttggg tttgtaggta agaatggtgc aggtaagact acaacaatga
    81601 aaatggtact tgggttactt aaaccagata gtggaactat agatgtttgt ggtgagaaag
    81661 tgacctatgg gaaaacaagt tctaatcgtc atgtaggtta tctgcctgat gttccagagt
    81721 tttacaacta tatgagacca cttgaatatc tttctctttg tggtgaaatt acgggacttt
    81781 caaaaaaaga aatacagata aggagtgaag agttgttatc acttgtgggt cttggaaatg
    81841 aaaagagacg aataggtggg ttttctcgtg gaatgaagca acgacttggt atagctcaag
    81901 ctttgctttc acgccccaaa ttacttattt gtgatgaacc aacaagtgca cttgaccctg
    81961 ttggtcgaaa agaaatatta gatattatgc ttaaaatcaa agactcaaca actgtaatat
    82021 tttcaacaca tatactatca gatgttgaaa gaatctgtga ccatgttgct atattaaaca
    82081 aaggaagcat tgcccttagt ggtacacttt cagaaataaa aagtatgcac ggaaaggata
    82141 gacttttact ggagtttgca agtaatgatg aaattcaaaa gtttaagtct agtgatggta
    82201 ttaaatcctt actaaaagat tcagaagaaa ctaatatgga aattgttttg catggtaaag
    82261 atataaaagc aatacaaaaa acagttatat ctacactcgc agaaatgaat ctttgtccag
    82321 taaagatgga actaatagaa ttatcacttg aaaatttatt tttggaggta gtaaagtgag
    82381 agaatacata gcatttacaa aaaaagaatt taaagagaat ttaagaaatt ataaattatt
    82441 tagtttaatt attttatttc taatatttgg tataagtagt cctatttctg caaaatttat
    82501 gccagacttg attgctcatt ttgcaccgac tttaaaagtt actgctgcac caactgcttt
    82561 agattcttgg acacaatttt ttagcaatat ctctggtctt ggtatgagtt taactctaat
    82621 tattttttgt aatattttat caaatgaata ttctaaaggg acacttgtta ttatgctgac
    82681 taaaggttta tcacgttcat ctatagtatt gtctaaattc tctgttacgg tgattattat
    82741 gacaattggt ttttggttga gttttttatt tgcttatggc tatacaatat atttttggcc
    82801 aactgcaaat cttaatcata ttatattttc agcatttaat ttatggctta taggaattat
    82861 gtatattagt gtattaattc ttgggtgtgt actatttaga ccagcatttg ccagtgtttt
    82921 acttgtattg gtggcaactc ttttattgag tttaatttct attcctaaac agattgcacc
    82981 ttatactcct aatttcttga tgtcaaaaaa tatagacttg atttcaggga aagtggcaat
    83041 gccagaattt attattccaa ttattataac agttcttatt tctgtagtat gtttactagc
    83101 agctgttatt ttatttaata aaaaaccagt ttaataatac ctttatcaca aggtaaagta
    83161 atcttatgtt gttaaaaact acacctaaaa atcaaaaaga cttggactta agtttcaagt
    83221 ctttttgatt tttaatatat agaattaagt gtagaaaata atacaaataa tattatttgt
    83281 atcaaataaa tataagaata tttaattatg ttaaaatata ctaaaaatta ctttaaaagt
    83341 gataaaatta gtataagtaa atattttaaa ggggtgtaga tatggaaaag tcaaaagtat
    83401 atttttgtga tttatactca aattcgcaaa ataaaaacgt accaaacaat gtaagaagat
    83461 tatttgatga agcaggattc aaagatttaa tagaaaagaa tgaccaagtt gcaattaaac
    83521 ttcactttgg agaaaaggga aatactacat atatgagtcc tgtggcagtt agacaagtgg
    83581 ttgataaggt taaagactgc gaaggaaagc catttttaac agatacaaat acactgtata
    83641 cagggagtag aacaaattct gtagaccatc ttacaactgc tatagaaaat ggatttgctt
    83701 atgcagttgt aaatgcacca gtaataattg cagatggatt atatagtaga aattatgaga
    83761 atgtaaaaat agacaaaaaa cattttgaaa gtgtaaaaat aggtggagaa atttataatt
    83821 cttctgcaat gatagtaatg agtcatttta aaggtcatga agcagcaggt tttggaggag
    83881 cattaaaaaa cttagctatg ggatgtgcaa gtgcagcagg aaaacaaatg caacattctg
    83941 atgttactcc agtagtaaag gaaaagaagt gtgtaggttg tggaaagtgt gttaattctt
    84001 gtcctacaaa agctataagt atagtggata aaaaagcagt tatagattct gatgtatgtt
    84061 atggatgtgg agaatgtcca actgtctgtc caactagagc agtaactata caatgggaaa
    84121 gtgactcaga tgtgtttgtc gaaaagatgg cagaatacgc ttatggagca gtatcaaata
    84181 aaaaagacaa ggtagggtat ataacttttg ttatgaatgt aactccactt tgtgattgtg
    84241 taccttggtc aggtagacca attgcccatg atataggaat attagcatca acagaccctg
    84301 tagctattga acaagcatgc tatgatttga tttgtaagga aatgggtcat gatgttttca
    84361 aacatgaaca tcctcatgta aatggaacta gaataataga ctatgcatgt gaaatgggta
    84421 tgggaagtaa agaatatgaa ttaataaaat tataagaata gtagcactta aatgcatata
    84481 attattgtaa gagaaatcta aaagtatcaa aggagtatgc atttatgaaa atttactatg
    84541 agaaggaaaa cagcaagaag gctaatgtaa acaatattcc aagtgtattt gcgtttaatt
    84601 ttctaagaaa ctttttgact agcaaagagt atgaggaaac tagaaaagaa tattttataa
    84661 ataatctaac aaaaagtcag gttaatcaag ccatgaagga tttaaaatgg ctatttagag
    84721 aatatgaagg cttagaggtt attacaatgg aaagcttgga tggagttaag acaaggatag
    84781 ttttataaac cagtaagaat tatattctaa taaaaaatac tgttttaata ataatatgta
    84841 taatccattt actaatatta ttttgaagca gtattttttt gtgtatagta aacttgtgtc
    84901 taaaataaag ttgaccaata aatgttatat atgcaatact atatataata agtaaactac
    84961 ataaaaatat taagttgaca aataggagga tatatggaaa aatacataat aaaattaaaa
    85021 aataaagtat tgagagaaaa agaaataagt tatgaagaag ctcttaattt aataagcctt
    85081 gatacaaata ataaaaacga ttttgatatt ctattaaaat ctgcaaatga aataagagaa
    85141 tattttatgg gaagaaaagc agatttatgt acgataatga atgctaaatc tggcaaatgt
    85201 agtgaagact gtaaattttg tgctcaatca tctcattata aaactggtgt agaagaatat
    85261 tcattattag attacaatga aatcttaaat agagctaaag agatggagag taaaggagtg
    85321 catagattct cattggttac aagtggtaaa ggtatgtcag gaaaggagtt taataatatt
    85381 ttaaatatct atgaaggatt gagggaaaat actaatttaa aattatgtgc atctttaggt
    85441 attatagatt atgagcaagc taaaatgttg aagtcagcag gtgtgactac atatcaccac
    85501 aatgttgaga cgtgtagaga taattttcat aatatatgta caacacacac atataaagat
    85561 aggataaaaa ctataaaaga tgctaaaaaa gctgggctag atgtatgtgt aggtggtata
    85621 attggaatga atgagagtga agaacagaga ctaaaaatgg cttttgaaat acgagaatta
    85681 aatgtaaaat catttccaat aaacatttta aatcctatta agaatacacc aatggaaaat
    85741 tatgatgtat tagaaccaat ggaaatacta aaaacaacag cagtatttag gtttataatt
    85801 cctaatgtgt acataaggta tgctggtgga aggctatcat taaagggata tgacaaagtt
    85861 ggatttaatg ggggagtaaa ttctgcaatt gttggtgatt atttgacaac tgttggaagt
    85921 gggattgaaa atgataaaaa aatgattata gagcaaggat ttgaacttta ataaatactg
    85981 cttaaattaa ttaatatact tttagataat tataaaagta tattaatttt tttttgcaga
    86041 ttaatttaaa tattaaaatt gaattataag ttgcaatatt ttgaaaaaag ggaaaaatat
    86101 caaaatttat ataaaatggt tgcaaatgga aaaaagatgt gatagtatct aggtaaccgg
    86161 ttaagtaaaa cggtttccta aattttgggg gtgaacttct tgagtataac tataaaagaa
    86221 attggcgaat tggctggtgt ttctaaaaca actgtgtcaa aagtcattaa taataaagat
    86281 gaaaatataa gtcaggcaac aagagaaaaa attttgaaaa taatgaagga aaaaaattat
    86341 gtaccaaata aattagcaca aagtttagta actaaaaaaa ctaatactat agggcttctt
    86401 ataccagata tacgaaatcc attctttaca gatgtatcaa gaggtgtaga agacaaagct
    86461 aatgaagaag gttacaatat aattttatgt aatacagatg aagatgctaa aaaagaatat
    86521 gaaggaataa gaacactatc agagaggatg atagatggaa ttatatttgc agcatcttca
    86581 aatacaaact ggaaagaagc aaattataaa gatataaaaa taccaactgt cttgattgat
    86641 aagaagataa gtatgaacaa agaaacctta aaaggaattg ttaaaataaa taactttgaa
    86701 ggggcctata tagctacaaa acatttatta gatattggaa ataagaaaat aatataccta
    86761 agtggtccac ttcaaaatga aatagcagta gatagattag aaggatataa aaaggctcta
    86821 atcgagtgta atttaagcta caatcctgct tatgtatttg aaggaaaata taagattgaa
    86881 tggggacaag aatttataaa aaatttagaa aagatagatt ttgatgcaat attttgtgca
    86941 aatgatttga ttgcaatagg tgtcataaga ggtcttaaag aaagaggatt aagtatacca
    87001 aatgatataa gtgtcgtggg atttgatgat attcaaacat caagtctaat aagcccttct
    87061 cttaccacag taaaacagcc gtcttatgat ataggatata aagccagtga aatattgata
    87121 aattgtttaa gaggagataa aaaagaatcg tttgatgaat tgattttcaa accagaattg
    87181 gtcataagag attcaacaaa agaaagtgaa taacagcacg agagacataa atagatatgt
    87241 aaaggagtaa tgtaatggga aatatagttg tcataggaag tgtaaacatg gacatggtat
    87301 gttctgtaga taaaagacca gaaaaaggag aaacagtatt aggtaatagt ttttttacat
    87361 cacctggagg aaaaggggct aatcaagcta tctcagcttc taaactagga gcaaatgtaa
    87421 aaatgatatc atgcataggg gaagatggct taggagagga gttaataaga aattttagaa
    87481 cgaataaagt tgattatagc ttagtatcca gaaataatca caaaagttct ggtgttgctg
    87541 ttataacatt atgtgaaaat gataatagta ttgttgttgt accagggact aatgagctag
    87601 tagatataga attaattaaa aagaatgaag aagagataaa gaatgcagat atagtattgc
    87661 tacaattaga gattccatta aaaacaataa attatgtagt gaatttctgt tttgaaaata
    87721 ggattagggt tttattaaat ccagcaccag cagtaaaact aaatgaagat ataatagaaa
    87781 aagtaactta cttaacacca aatgaacatg aatataagat agtttttgac acaaatgaag
    87841 ggatagaaga agtattaaaa aaatatccaa ataaacttgt aataacagaa ggaaaaaatg
    87901 gagctagatt ttatgatggt gaggaaatca agcatgtatc ttgtataagt gttgatgttc
    87961 aagataccac aggagcagga gatacattta atggagcatt ggcagtggct ataacagaag
    88021 ggaaaaattt atatacagca gtagaatatg cagtagtagt atcaggtctt tctgtaacta
    88081 aactaggtgc acaatctggt atgccctata aagaagatgt tgaaaagtat ttaaataata
    88141 aataaaaatc taatttgttc aaatttaaaa ctattaaaaa tggaggttaa ttatgagagt
    88201 gagaaaaatt ttatctttag gaattgctgg aatactagca ataggaatgt taacagggtg
    88261 ttcaatggaa ggaccaagta aatcagataa taaaggtggt tcagacaaga aagatttaac
    88321 tattggagta tctacaataa ctcttcaaca tcaatttttt atagatattg atgagggaat
    88381 aaaagaaaaa gctaaagaat taggtgtgaa agttatagta aatgacccag accaagatgt
    88441 agctaagcaa acatcagcaa tagaagattt tatacaacag aatgtagatg gaatgatagt
    88501 acttggaact gataattcgg ctatagtacc agcagtagaa ggagcatttg aaaaaatgcc
    88561 agtagttaca gtagatgctg tattaaatac tgaaaatatt acaagttatg taggaacagt
    88621 tagttatgat gctggtaaaa aattagggga atacactaaa aaatacatag atgaaaagtt
    88681 aggtggaaag tcagaaatag caatagtgac agatttaaaa tctcaaatac aaatgcagag
    88741 aatagatgga tttaaagatg cattaaaagg ttcagcaaat gttaagatat taaattcaca
    88801 accaggatat gacagagaag aatctcttaa tacagtagaa aacttaattc aatctaatcc
    88861 agatgtagat ataatatatg caacagctga aaatagtgta ctaggagcta aagctgcact
    88921 tgaatctgca aaaaataagg atgttaagat tgtaggattt gacttaactg aagaagcatc
    88981 aagtggaata acagatggaa ctattcttgc tatgattcaa caacaaccta aagagatggg
    89041 acgtttagct gtagaagcag tagtaaaagc tataaaaggg gaaaaggtag aaaagaatat
    89101 accagtacca gctttacttt atgataagga aaatataaaa gactttaaga attagtaaaa
    89161 taaaatgaga ttatttgaaa gaaatcctat ttaaaaagga gtgtcattat gagtaatata
    89221 attctgaagt taagtaatat tgctaaagaa tttcctggtg tcagagcatt agataatgtt
    89281 aattttgagt tatttcatgg cgaagttcat gcactactgg gtgaaaatgg tgctggtaaa
    89341 tcaacaatga taaagatttt aactggggca cattcgaaaa cttctggaaa atttattttt
    89401 gaaggcaaag aaatagagaa tatatcccca gatatctcta aaaagatagg tataaatgcc
    89461 atatatcaag aactaacagt ttttgacgaa ttaacagtag cacaaaatat ttttatggga
    89521 aaagaaataa atggcaaagt cttaaccaat gacaaaaaaa tgaatgaaga agctaaaaag
    89581 attttcgata atatgggaat agatataaat ccaaatagtt tagtcaaaga gcttagtata
    89641 gctcaaaaac aaatggtaga aatagcaaga gttttatcat cagaaactaa agtattaata
    89701 atggatgaac ctacttcttc aataagtaaa aaagagactg aaatactttt tagacttata
    89761 aatgatttaa aagagagtgg agttagtata atatatatat cccataggat ggaagaactc
    89821 tttgagattt gtgacagaat aactataatg cgagatggga aaacgatttc gactttaaat
    89881 accaaagatg tatcgtctga ggaagaatta gttaatttaa tgatagatag aaagctagac
    89941 caatttttcc caaaaagaaa agtagaaata aaagaagaaa ttatgcgagt ggaaaatcta
    90001 actaagaaca atgtttttaa tgatattagc tttaatataa gaaaaggtga aatattggga
    90061 ataggtggac tagttggaag taagagaagt gaaatagtag aagctatatt tggacttaga
    90121 acatatgatt ctggaaaaat atatttaaac aatgaagaag taaagtttaa aactccatca
    90181 gatgcaatag aaaatggact aggattaata acagaagata gaaaaggtac tggattgttt
    90241 ttacaaatga gtgtcaaaga aaatacaact atggctgggt taaaaaagat atctaagttt
    90301 aaatcaatta tagatagaaa aaaggaaaaa gagattttag aaaaatacat agaagcttta
    90361 aagataaaaa caccacatat gaatcaagtt atacaaagtt taagtggtgg aaaccaacaa
    90421 aaagctataa tagcaagatg gcttttatta caaccagata tattgattat ggatgaacca
    90481 accagaggta tagatgtaaa tgctaaggca gagatataca atctaatggg agatttagtg
    90541 gagagtggtg taagtataat aatgatatct tctgaaatac cagaattaat atcaatgagt
    90601 gacagaataa tggttatgag agaaggtcat ataagtggat ttttagaagg tgaagaaatg
    90661 gttgaaaata atgtattaaa attggctttc ggaggtaaaa ttaatgagtt caataactaa
    90721 gcataaagaa gaaaaatctt ctccattatt gacaaaatta acaagtgtat ttagagacca
    90781 agggagtgca gctgtaggac ttgtaataat ttttataata atgagtgtag cttcatctaa
    90841 ctttttaact ttagataatt taattaatgt tggaagacaa atatcaataa atgcaatact
    90901 tgcagtaggt atgacatttg taataattac aggaggaata gatttaagtg taggagcagt
    90961 aattgcttta gtaggtacat tttgggctac aacagtagtg aattataatg cacctatatg
    91021 ggtaggtatg atacttgcat tagcaatagg gacaatttta ggagtcataa aaggtgcaat
    91081 tatttcaaca caaaaactac ctccattcat tgtaacttta gccatgttaa cgataataag
    91141 tggggcaagc tttgtattta caggaggaag acctatatca gtaaatacag atgcatttaa
    91201 gatgctcggt agaggatata ttggaccaat accaatacca gttataatta tgattatagt
    91261 tgtaatagca ggacattttc tattaaaaag aactaatttt ggacgtcatg tacatgcagt
    91321 aggtggaaat gaagaggccg ctagattatg tggagtaaaa gtaaataaag ttatagtaaa
    91381 agtatacgca ctagctggac tactaacagc attagctggg ataatactat catcacgttt
    91441 ggcatcaggt tcaccaactg ttggagatgg agcagaattg gatgctatag cagccgttgt
    91501 gcttggtggt actaatatga tgggtggttc tggttctata gtaggtacat gtataggtgt
    91561 cggaataata ggaatattag gaaatggatt aaacttatta agtgtatctt catataatca
    91621 aatgattata aaaggtttgg taatgttatt tgctatatgg ataaataata taaaattaaa
    91681 aaaatcagct aaatctaaat agtaattaaa ttttagctta taaactataa aaattattaa
    91741 gtttttgtat atatt
//
LOCUS       DAYAKB010000006        88493 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.006, whole genome shotgun sequence.
ACCESSION   DAYAKB010000006 DAYAKB010000000
VERSION     DAYAKB010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 88493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.006"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..410
                     /locus_tag="ACGI3L_000536"
     CDS             <1..410
                     /locus_tag="ACGI3L_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4004 family protein"
                     /protein_id="HFG9196267.1"
                     /translation="IANMFMKKDINKEFDIDFILSKEVICNYTKEIFQNLYKKEQSIG
                     KKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKIYLFRKFGVPFVVG
                     CLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(710..1297)
                     /gene="rbr"
                     /locus_tag="ACGI3L_000537"
     CDS             complement(710..1297)
                     /gene="rbr"
                     /locus_tag="ACGI3L_000537"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HFG9196268.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(1383..1820)
                     /locus_tag="ACGI3L_000538"
     CDS             complement(1383..1820)
                     /locus_tag="ACGI3L_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9196269.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            1924..2922
                     /locus_tag="ACGI3L_000539"
     CDS             1924..2922
                     /locus_tag="ACGI3L_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HFG9196270.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(3042..3968)
                     /locus_tag="ACGI3L_000540"
     CDS             complement(3042..3968)
                     /locus_tag="ACGI3L_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HFG9196271.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            4353..5957
                     /locus_tag="ACGI3L_000541"
     CDS             4353..5957
                     /locus_tag="ACGI3L_000541"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9196272.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            6773..8044
                     /gene="serS"
                     /locus_tag="ACGI3L_000542"
     CDS             6773..8044
                     /gene="serS"
                     /locus_tag="ACGI3L_000542"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFG9196273.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            8322..9827
                     /locus_tag="ACGI3L_000543"
     CDS             8322..9827
                     /locus_tag="ACGI3L_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFG9196274.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            9941..10639
                     /locus_tag="ACGI3L_000544"
     CDS             9941..10639
                     /locus_tag="ACGI3L_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9196275.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            10924..12012
                     /locus_tag="ACGI3L_000545"
     CDS             10924..12012
                     /locus_tag="ACGI3L_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196276.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            12251..13441
                     /locus_tag="ACGI3L_000546"
     CDS             12251..13441
                     /locus_tag="ACGI3L_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9196277.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            13532..15034
                     /locus_tag="ACGI3L_000547"
     CDS             13532..15034
                     /locus_tag="ACGI3L_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HFG9196278.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            15106..16362
                     /gene="glyA"
                     /locus_tag="ACGI3L_000548"
     CDS             15106..16362
                     /gene="glyA"
                     /locus_tag="ACGI3L_000548"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFG9196279.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            16534..19308
                     /locus_tag="ACGI3L_000549"
     CDS             16534..19308
                     /locus_tag="ACGI3L_000549"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HFG9196280.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(19373..19558)
                     /locus_tag="ACGI3L_000550"
     CDS             complement(19373..19558)
                     /locus_tag="ACGI3L_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFG9196281.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            19933..21111
                     /locus_tag="ACGI3L_000551"
     CDS             19933..21111
                     /locus_tag="ACGI3L_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFG9196282.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      21238..21323
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            21441..24359
                     /locus_tag="ACGI3L_000552"
     CDS             21441..24359
                     /locus_tag="ACGI3L_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HFG9196283.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     ENENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNLGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      24545..24630
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            24730..25392
                     /gene="zmp1"
                     /locus_tag="ACGI3L_000553"
     CDS             24730..25392
                     /gene="zmp1"
                     /locus_tag="ACGI3L_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HFG9196284.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(25514..26476)
                     /locus_tag="ACGI3L_000554"
     CDS             complement(25514..26476)
                     /locus_tag="ACGI3L_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9196285.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(26646..27836)
                     /locus_tag="ACGI3L_000555"
     CDS             complement(26646..27836)
                     /locus_tag="ACGI3L_000555"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFG9196286.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            28142..28588
                     /gene="bilQ"
                     /locus_tag="ACGI3L_000556"
     CDS             28142..28588
                     /gene="bilQ"
                     /locus_tag="ACGI3L_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin utilization transcriptional regulator
                     BilQ"
                     /protein_id="HFG9196287.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            28590..29684
                     /gene="bilR"
                     /locus_tag="ACGI3L_000557"
     CDS             28590..29684
                     /gene="bilR"
                     /locus_tag="ACGI3L_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin reductase"
                     /protein_id="HFG9196288.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            29772..30302
                     /gene="bilS"
                     /locus_tag="ACGI3L_000558"
     CDS             29772..30302
                     /gene="bilS"
                     /locus_tag="ACGI3L_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein BilS"
                     /protein_id="HFG9196289.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(31238..32614)
                     /locus_tag="ACGI3L_000559"
     CDS             complement(31238..32614)
                     /locus_tag="ACGI3L_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196290.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDEKDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDSIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            32882..34054
                     /locus_tag="ACGI3L_000560"
     CDS             32882..34054
                     /locus_tag="ACGI3L_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9196291.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYAIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            34068..34715
                     /locus_tag="ACGI3L_000561"
     CDS             34068..34715
                     /locus_tag="ACGI3L_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HFG9196292.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            34717..35226
                     /locus_tag="ACGI3L_000562"
     CDS             34717..35226
                     /locus_tag="ACGI3L_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HFG9196293.1"
                     /translation="MSQQNTGNVIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(35590..36702)
                     /locus_tag="ACGI3L_000563"
     CDS             complement(35590..36702)
                     /locus_tag="ACGI3L_000563"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFG9196294.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            37066..37266
                     /locus_tag="ACGI3L_000564"
     CDS             37066..37266
                     /locus_tag="ACGI3L_000564"
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFG9196295.1"
                     /translation="MVGGGDIVKLFMKDNLIDDYYIYILTIILGRGISLFKSGIDKTN
                     LNFKKASNIGELVKLEYSKKQK"
     gene            37511..39238
                     /locus_tag="ACGI3L_000565"
     CDS             37511..39238
                     /locus_tag="ACGI3L_000565"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196296.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            39238..41028
                     /locus_tag="ACGI3L_000566"
     CDS             39238..41028
                     /locus_tag="ACGI3L_000566"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196297.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(41190..41498)
                     /locus_tag="ACGI3L_000567"
     CDS             complement(41190..41498)
                     /locus_tag="ACGI3L_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196298.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(41760..42308)
                     /locus_tag="ACGI3L_000568"
     CDS             complement(41760..42308)
                     /locus_tag="ACGI3L_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196299.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(42411..43082)
                     /locus_tag="ACGI3L_000569"
     CDS             complement(42411..43082)
                     /locus_tag="ACGI3L_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9196300.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            43475..44383
                     /gene="garR"
                     /locus_tag="ACGI3L_000570"
                     /pseudo
     CDS             43475..44383
                     /gene="garR"
                     /locus_tag="ACGI3L_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
     gene            44519..45901
                     /locus_tag="ACGI3L_000571"
     CDS             44519..45901
                     /locus_tag="ACGI3L_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate:H+ symporter"
                     /protein_id="HFG9196301.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            45972..47408
                     /locus_tag="ACGI3L_000572"
     CDS             45972..47408
                     /locus_tag="ACGI3L_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HFG9196302.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNGGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(47594..48448)
                     /locus_tag="ACGI3L_000573"
     CDS             complement(47594..48448)
                     /locus_tag="ACGI3L_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HFG9196303.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(48716..49039)
                     /locus_tag="ACGI3L_000574"
     CDS             complement(48716..49039)
                     /locus_tag="ACGI3L_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HFG9196304.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNKNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            49242..49871
                     /locus_tag="ACGI3L_000575"
     CDS             49242..49871
                     /locus_tag="ACGI3L_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196305.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            50183..50692
                     /gene="ruvC"
                     /locus_tag="ACGI3L_000576"
     CDS             50183..50692
                     /gene="ruvC"
                     /locus_tag="ACGI3L_000576"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFG9196306.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            50685..51287
                     /gene="ruvA"
                     /locus_tag="ACGI3L_000577"
     CDS             50685..51287
                     /gene="ruvA"
                     /locus_tag="ACGI3L_000577"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFG9196307.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            51394..52413
                     /gene="ruvB"
                     /locus_tag="ACGI3L_000578"
     CDS             51394..52413
                     /gene="ruvB"
                     /locus_tag="ACGI3L_000578"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFG9196308.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            52731..53756
                     /gene="queA"
                     /locus_tag="ACGI3L_000579"
     CDS             52731..53756
                     /gene="queA"
                     /locus_tag="ACGI3L_000579"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFG9196309.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            53768..54253
                     /locus_tag="ACGI3L_000580"
     CDS             53768..54253
                     /locus_tag="ACGI3L_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HFG9196310.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            54332..55453
                     /gene="tgt"
                     /locus_tag="ACGI3L_000581"
     CDS             54332..55453
                     /gene="tgt"
                     /locus_tag="ACGI3L_000581"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFG9196311.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            55587..55880
                     /gene="yajC"
                     /locus_tag="ACGI3L_000582"
     CDS             55587..55880
                     /gene="yajC"
                     /locus_tag="ACGI3L_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFG9196312.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            55938..56300
                     /locus_tag="ACGI3L_000583"
     CDS             55938..56300
                     /locus_tag="ACGI3L_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HFG9196313.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            56366..56509
                     /gene="scfA"
                     /locus_tag="ACGI3L_000584"
     CDS             56366..56509
                     /gene="scfA"
                     /locus_tag="ACGI3L_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HFG9196314.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            57135..59030
                     /locus_tag="ACGI3L_000585"
     CDS             57135..59030
                     /locus_tag="ACGI3L_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HFG9196315.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            59492..60895
                     /locus_tag="ACGI3L_000586"
     CDS             59492..60895
                     /locus_tag="ACGI3L_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HFG9196316.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      61067..61152
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            61276..67239
                     /locus_tag="ACGI3L_000587"
     CDS             61276..67239
                     /locus_tag="ACGI3L_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M60 family metallopeptidase"
                     /protein_id="HFG9196317.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSDSESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDEQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSKSTLE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELARYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRIEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDANTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     gene            67449..69329
                     /locus_tag="ACGI3L_000588"
     CDS             67449..69329
                     /locus_tag="ACGI3L_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HFG9196318.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKVTINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGSGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGDDRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNDKLPQKTVEELK
                     RLNPSKVVVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            69696..71297
                     /locus_tag="ACGI3L_000589"
     CDS             69696..71297
                     /locus_tag="ACGI3L_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HFG9196319.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPAITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDNKVFEHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKSVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            71516..73114
                     /locus_tag="ACGI3L_000590"
     CDS             71516..73114
                     /locus_tag="ACGI3L_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9196320.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVADQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLKPNIEGTVDTSKAGTYVLNVSAFDNFGQKCEINVNVKVIINTSTKDPNS
                     YEFKAMVSNEMYNLVNSYRKEKGKKSLRELDSLAGMANAWSKYMDEKKIFAHEIDGKN
                     AAEVFSGFGMRTDENIAYLPMNVKSVYTSKDAKEIAKSVFDLWKKSSKYNDNMLKEEF
                     YSFGFGMYVSNQREVNATMEFLNS"
     gene            73407..75587
                     /gene="slpA"
                     /locus_tag="ACGI3L_000591"
     CDS             73407..75587
                     /gene="slpA"
                     /locus_tag="ACGI3L_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HFG9196321.1"
                     /translation="MNKKNLAVVMSAVTVIGSAAPVFAAAEDSFPNGNTTVSSSKYSD
                     IERILKKYVADGVTGITVNFFDKKGNPKGVSISSLEASQISYVKDEIKDLKAGEYAKI
                     SVKITDGTEKKYDDTLLKELDSNAVVTKVGTATTVKIVDQDGNSIENDAKLKLQKYDT
                     TTSAYVDGATKDEVLAATKAAVKTSKFTDKTGNNATGTVAITATYADAVAGAIKLKYD
                     TQAAVAPTLDTAVASLDGTKEIYDFSKPVITVNTTDGTSKLSFEKTGEKVGAVESNVT
                     VIAASDETVTISGDAKEKAEALAKKYVFKDTELEDAYKTVTASDFEKTDNDYYEVVLY
                     PTGKRLNTASTYASSNYKPELPTSDRVDTPAIITLRSTNKNNLKSALDELRTYNNSYS
                     NNSVLAGDDRIETAIEISKDSYNADGGIKGDYVEANEVVLVGSQSIVDGLVASPLAAV
                     KDAPLLLTSKDKLDSSVKSEIKRVMGLDDKTGITSKKTVYIAGGENSVSKEVANELKD
                     MGLKVERLSGDDRYATSLEIADEIGLNHNKVFVVGGTGLADAMSIASVASNKEMPIVV
                     VDGKGKDLSTDAKDFIGSAYVDIIGGKSSVSEDMEDAIDDATGKSPERVSGDDRQDTN
                     AEVIKTYFEKDNSDSVISTGVKNFYVAKDGSTKEDQLVDALAIAAVAGHNEAPIVLAT
                     DSLSSDQSVAISKVTNSDDSKKLTQVGKGIADSVIKRIKDLLEL"
     gene            75823..78168
                     /gene="secA"
                     /locus_tag="ACGI3L_000592"
     CDS             75823..78168
                     /gene="secA"
                     /locus_tag="ACGI3L_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFG9196322.1"
                     /translation="MSVLDTILDKADEQEIRRLNVIVDKIESLEKDIENMSDDELKKM
                     TDLFRDRLKKGETLDSLLPEAFAVAREASKRVLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVVTVNDYLAQRDKELMQPVYEFLGMSVGVIIADLI
                     PEVRKVQYNCDITYGTNNEFGFDYLKDNMVTKKFDKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGEGDEDSKLYELANSFIKTIKEEDYELDRKDKTVALKESGIDKAESFFGIKN
                     LTDIENIELYHHINQALRGHKLMEKDVDYVVVNQEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKDESKTMATITFQNFFRLYNKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPIIRADLHDKVFRTEKEKYQAVVEEVIRIHKTKQPILIGTVSVEKSEMLSGMLKK
                     EGIKHQVLNAKENDKEALIVSKAGKLGSVTIATNMAGRGTDIALGAGDKEEESRVKEL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKSIEKLMKR
                     PNSNKNNSIESKSLTKAIERAQKGVEGKNFELRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIQVDIQNMVKDIIKEAAAEYLTKRKRDYYGYFKHLYNTFMPADTLLIPDLDNKS
                     IEDIIDSTYEISKRVYDLKKMVVGLDKITEMEKIVLLKVVDQYWVEHIDAMEQLKQYV
                     GFKSYAQKDPFKEYAMEGYEMFESLNKNIRETTIQYLYKFN"
     gene            78512..80383
                     /locus_tag="ACGI3L_000593"
     CDS             78512..80383
                     /locus_tag="ACGI3L_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HFG9196323.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            80490..81197
                     /locus_tag="ACGI3L_000594"
     CDS             80490..81197
                     /locus_tag="ACGI3L_000594"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFG9196324.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAKEIILKYLEEYPEAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDDLELNKTQYVHAP"
     gene            81228..83345
                     /locus_tag="ACGI3L_000595"
     CDS             81228..83345
                     /locus_tag="ACGI3L_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9196325.1"
                     /translation="MQISKKIISLLTAAFLSIVLPSNVVNASNKDSLIGSGRWETAIK
                     ISQNGWLRSDNAVLVNDNSIADALSATPFAKLKDAPILLSGSKELDFRTKSELKRLGV
                     KNVFLVGGSNALGVNVENELKSEKITVERIFGNDRYETSLKLAEKLNNEKDISDIIVV
                     NGEKGLADAVSVGSIAAQNYMPIILSDSNLGVEVANKFIKAQNIKNSYIIGGLNSISN
                     EIEKNLPNSKRISGNNRNETNANVIKEFYKETDLRNAYITKDGMKKQSDLIDSLSVGV
                     LAAKNNSPVVLVGNKIDSIQKDVLNTKIFSTVTQVGGIGNENVYKDILDMQEETKYTV
                     ETIEELDSALKKVDANDIIKFRPDKKISESFKLETEKAIKVDLYGEYSQSITINMPNG
                     ELNNTGDISKTLILKDIKDGTLTNSGYINQMDISDDNGCKIENENNGQIWIVTIFSSA
                     KDVNIRNDGTITKIDNDSSSTNIRNSGKIDTVSGNKEPGISGNKPNTNNTDKDDDSDT
                     AAGLSPKISACSPLENNQIMLTVPQKPKNSNYKIYYRVLSYKPSAMRVGDRININDWD
                     LVEDTEPLKVNAKNGSYIEVVEIDYTRKKVSRWGRAGATDDGFKIVANGIKSTVSVDE
                     NSKVTISVTGYNGNKVYYRIKTTKPEAMNVGDEIDSSWKSTSNSDIILEGNKVNGLYV
                     ELASGENNKVEKWGATDKIEIVS"
     gene            complement(83410..83826)
                     /locus_tag="ACGI3L_000596"
     CDS             complement(83410..83826)
                     /locus_tag="ACGI3L_000596"
                     /inference="COORDINATES: protein motif:HMM:NF016060.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFG9196326.1"
                     /translation="MEENFLILKKHLETILYLFFGALTVLINIITYLFFTRIINFTFL
                     LSNSLSWSIAVLFSYITNKFFVFKSEKTEFLFLLKEFVSFLSCRLFSGFIEILLMYLM
                     IDLFSLNDILVKIGTNIIVIILNFVFSKVVVFKHRN"
     gene            84001..86412
                     /locus_tag="ACGI3L_000597"
     CDS             84001..86412
                     /locus_tag="ACGI3L_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9196327.1"
                     /translation="MRKYKLKKLSKLLVLLTVCFLIVSTIPVSAEKNKILTGVETAEY
                     SESYLQYLEDVKNGDIAKYNGVIPTPYEMEGTTLKTNVRSSLPASYKSSVSYDPRKLD
                     LTTPAKDQGKLNTCWAFSGMSTLEAYLKLKGYGTYDLSEEHFRWWSTGGIHGWNLTDM
                     TGSSNVTAIGYLTAWAGPKLEKDIPYNFKSEDEGATRPQNMDTAPTQFNVTDVVRISK
                     DKTSVKNAIMQYGAVTSGYAHYSAYLSDDENSYNCNDKSEPLNHSVSIVGWDDNYSKD
                     KFKPSVRPESNGAWLVKSSWGEFNSEKGFFWISYEDKTLLKDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            86709..88286
                     /locus_tag="ACGI3L_000598"
     CDS             86709..88286
                     /locus_tag="ACGI3L_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HFG9196328.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT        35081 a        10022 c        15452 g        27938 t
ORIGIN      
        1 atattgcaaa tatgtttatg aaaaaggata ttaataaaga atttgacatt gattttattc
       61 tcagtaaaga agttatatgt aattatacca aagaaatatt tcaaaattta tataaaaaag
      121 aacaaagcat aggtaaaaaa gaactgctta tattgagcat aatagagaag tttttagtta
      181 aatctataat aacttttgaa gagttaaaat tgatagtgaa tataatagaa gaaaatttta
      241 catcaatata caatgaaagt ggaaagattt atttgtttag aaagtttgga gttccattcg
      301 tagtaggatg tctggattat aaaaaagtaa agtttgaaaa agatgtagtt aagattattg
      361 aggttgactt gacaaaagaa ataaatgata taagtataaa gttatcatag tgtattatct
      421 tatataatgt attataataa tctacttaaa atacacttta tttaaatatt tagtttaaag
      481 atgagatttt atgtgagtgt gtaaaagtta aagatagatt taagtaggtt atagggatta
      541 gtaaacaata aaatgaacca tgatgaacta ctataaattg tatttaaact acattttcta
      601 cttatagtaa tatcaatggt tcattttatt gttattaaga taatacagta tttataaaaa
      661 tacttgatat aaatatagta aattgtttaa atagaattat tgccttaatt tattcaaata
      721 atgagttttt aaaatctaag aaatatcctt gtggatgaag acatacagga caagctttag
      781 gagcttcttt acctatatgt atatggccac aatgtgtaca tatccattgt atatcttcat
      841 ttcttctgaa taaagtacct tcttctaaat cagtagcata tctaccaaat ctatcaccat
      901 gaactttttc tatttcagct atattttcaa ataacttagc tatagattca aatccttctt
      961 cacgtgctgt ttttccaaag tttttatata catcatccca ctcttgaagc tcattatgtt
     1021 gtgcagcttt aaggtgttgt gctgtcttgt catataaatc tacagggtat gctcctgata
     1081 tacttatatt ttcaccagca aattctttta atttagaaaa gaattgtttt gcatgtgatt
     1141 tttcttggtc agcagtgtaa ttaaataaag actctattat atataatcct tctttttttg
     1201 ctacagatgc agaaatattg tatctatttc tagcttgact ctcacctgca aaagctctta
     1261 ataaattttc tttagtttta ctatctttta aattcatatt ctacctctct atcacaataa
     1321 atttttacaa tatttgattc tttttattta ttattccaat aggagatata attatgctca
     1381 atttagtcag catttttaaa attatcatta atttttttta aaattctaag aaattcttgt
     1441 ttttcatttt ctgtaatatt atggtatgcc gtctctttaa cttgtgttga gatgctatta
     1501 aaagtatctt ctataagcag tgcctttttt gtaagcttta tatacgtgat acgtttgtca
     1561 tttgtacatt tttgtctttc taaatatcct aggtttataa gtttattaac caacactgta
     1621 acagtggatt tatcttttcc tattttagct gcaatttctt tcattgtaag tattccatta
     1681 ttttcataaa gtgcagttaa aatatttcca tgagtaggta ttaactcacc taaaccattt
     1741 ttactgagtt tattttcaat gaatttaatc atactagcct ttgttttact tatgaaatgt
     1801 acaatatatt tatcttccat aaattattct ccaatcttta atctatttaa attagtttga
     1861 cataaaacta tttataaact ataattagtt taacataaaa ctaaatgtat tgggaggaaa
     1921 tttatgaata aaaaatttaa atcactatat attacagaag aagaaggaaa ttttagaaga
     1981 aatatagttg aaagagaagt ggatacattg ccagaaggcg aagttctaat aaaagtaaaa
     2041 tattcttctc taaattacaa ggatgcactt tctgcaaatg gtaataaggg tgttacgaga
     2101 aagtatcctc atacaccagg aattgatgca tctggtatag tagaatctag tagttgtgat
     2161 gattttaaaa ttggagaaga agttttagta acaggttatg acttgggaat gaatacttct
     2221 ggtggttttt cagaatacat aagagttcct tctagttggg tagttaaact tcctaaaaat
     2281 ctttcactaa aagaagcaat ggattatggt acagcagggt ttacagcagc tttatctgtg
     2341 tataaattta tagattctgt agacaagaat atgggagatg tattagtcac tggtggtact
     2401 ggaggagttg ctgtaattgc aactaaaata ttgattaaat taggttattc agttgtagtt
     2461 tcaacaggaa aattagaaga acaaaaagaa gtattactaa acttaggtgt taaagatgtt
     2521 atacataggt cagaagtgga tgataactca ggaagacctc tgcttagacc aagatgggct
     2581 ggagtaatag atacagtagg aggaaatact ctagcaacag caataaagac aactaattat
     2641 tgtggagcag taacaacttg tggtaatgca ggaggagttg attttacaag ttcagtatat
     2701 ccatttatct taaagggaat tactttatat ggtatagatt ctgtggattg cccaatgaac
     2761 ttaagattaa aaatatggga tttattatca aatgaatgga aattagatga tttagatgat
     2821 atggtaaatg tagtatcatt ggaagagtta aatgatagta tagattcaat aatggcagga
     2881 aaacatgttg gaagaacagt agttgattta gaaaaaatat aggtgaataa atttataatt
     2941 aggattatag gttttaagca aaaatgagat acttgaaatt tacttgtgag tatctcattt
     3001 ttttatgtaa aaagatttat gtagatgttt gtgtaaaaag attattcatg aacaattaat
     3061 tcaaatacat ctggtcttga atagtgacct tctgaatcaa aatctagtct actaagtact
     3121 attttttcta ggtctaaatc agctattagc atttcttctt tattgaaaat aggacctgct
     3181 acatattttc caaaagggtc aactatacaa cttcctcctg gacacataat ttctggttct
     3241 gcatctagct ctttatagta gttaaggtca gttggataca tatttttttc aacatattga
     3301 ttgcatccaa ttacaaaaca tcttccttct aaagcaatat gcttcatagt tgcttgccac
     3361 tcttctcttg aatctgcagt aggggctatg taaagtttta cacccttagc ataaagagct
     3421 gttctagcta atggcatata attttcccaa caaatcaacg aacccatttt tccatatgga
     3481 gtatcaacta ctgtaagagt acttccatct ccttctcccc aaatacatct ttctgttcct
     3541 gtaggtttaa gttttctgtg tttaccaatt agcttacctt ctggagagaa aaataagttt
     3601 gtgcaataaa gggtacaatt tatatcatta ccatctcttt ctgttatacc cattgataga
     3661 tatactcctg cttcttgtgc tgcttttcct aataaatctg ttgtagcact aggaactggt
     3721 acagaattat catagtatct tttccaatct tctctacctt ccattgttct acttccaaca
     3781 acaaatccaa atgaaagacc tcttggatat gcaggtatga atgcttcagg gaaaactacg
     3841 atatttgccc cttttctacc agcttcttta attaatccta atgctttttc aacagttttt
     3901 tctaaatcca ttatgactgg tgacgcctgg acaacagcaa ttcttacatt tttattttcc
     3961 ttgctcataa aaacctccta aaaaatattt aaattttttg cattgaatag attacatgag
     4021 atgttatttg agaactaaga tacttatatt gtgaataata atgtaactgt atatttaaaa
     4081 taatacatca tgatttaaaa aattacaatt gtacagatat aattgagttt agatatttaa
     4141 atttaacaac ttataatatt ttttcaatta gtataaagcc tattaatttg tcttatttac
     4201 aatgaatagt atttacttct tggcaaacaa taattaaaaa taaaactttt atatgattaa
     4261 actctaaaga aaaagtttat aaagaagata atataattaa gcagaaaata atgaaaaaaa
     4321 tttattaaag tagacaacgt aaggagaatt ttatgaaaga aaaaatttat tacaatggaa
     4381 atatcatcac aatggaagat tcaatatgtg gagatgctat tcttataaaa gacaaaataa
     4441 taaaaaagat aggaacaaaa gaagaagtat ttgctttgaa aaataaagat acagaaatta
     4501 tagatttaca aggtaagaca ttgatgccat cttttataga ttcacatagt cacttgatag
     4561 cttttgctac tactctaaag ctagttcctt tagaagatgc aaccagtttt aaagacatag
     4621 taaaaaaaat acaggatttc aaagagtcga ataatataaa aaaaggagac tggataattg
     4681 gattttcata tgataataat tttttagaag aaaataagca tccagataag agtgtactcg
     4741 atagtgcatc ttcagaaaat ccaatactaa tttcacatgc ttctggtcat atgggagttg
     4801 caaatacatt ggggttaaaa cagcttggtg ttaccaatga aacacgtgac ccagaaggtg
     4861 gacatatagg tagagtagaa ggcagtgaag aaccaaatgg atatttagaa gaaaatgcat
     4921 tttttaatgt agcatctaaa ataaaacaac catcatcaaa tgagattttt aattcaattg
     4981 aaaaagcaca gaacatatat ctaagctatg gtattacaac agctcaagaa ggtttaatgg
     5041 aagaaaatca atttaacatt ttaaaagcaa tggcaaatca aaataaatta aaaatggatg
     5101 ttgtaggata tgtaaatttg aaaaaaagta agtctgtagc agataataat agggagttta
     5161 taaaaaaata tataaataga tttaaaatag gaggttataa gattttctta gatggttctc
     5221 cacaaggtaa gacagcatgg ttgagtagac catatgaaaa ttcagatgat ggttattgtg
     5281 gatatcctat atacaaagat gaagaagtag aaaagtttat agatatttca ctaaaagaaa
     5341 agatgcaact cttaactcat tgtaatggag atgcagcagc agaccagttg atagatgcgt
     5401 ttgagaaagt tttaaattta aaagagcaaa gtagtgaaaa tcatataaga ccagttatga
     5461 tacatgctca aacagtaaga gaagaccaga ttgatgatat gaaagtaata aatatgatac
     5521 cttcatactt tgtagctcac acatattatt ggggtgatat tcatatcaaa aaccttggag
     5581 aagatagagc gtttaagatt agcccactta aaacaactat agaaaaggga ttaatttaca
     5641 ctcttcatca ggatacacca gtaatagcac ctaatatgct ggaaacagta tggtgtgctg
     5701 tcaatagaat tacaaaaaaa ggtatacaaa taggagaaaa tgaaaagata agcccattag
     5761 atgctttaaa gggtgttact ataaatgcag catatcaata ttttgaagaa gataaaaaag
     5821 gttcaattaa agaagggaaa ttagctaatt tgataatctt agatgaaaac ccacttacaa
     5881 tcgaccctat gaaaataaaa gatattaaag tattgcagac tataagagaa ggagaagtat
     5941 tgtattcttt gaagtagatg aaagttagat attttataat ctataaaaaa tagttttata
     6001 taataagtta ggtagaatta aataagatta cagttaaatc aacaattata tttttattaa
     6061 attttaatta ttgtattgaa gatttataag tataatttta ttgattctac ctttttaaat
     6121 aactgtcgat ttattaaagt tatctatgta ctatattaaa caattaagta gttattaatt
     6181 gaacttatta gtttattaaa aaactatgta tattactttg cagtaagact ttggaactaa
     6241 atctataata gcaaatttaa atttattaaa tagattacct tataacattt catataaaat
     6301 atattgtgaa tctgagaaaa ttactatttt tctttgagta ttttttgtaa gcagttctaa
     6361 aagattcaat ttcataccta ttacttgaat cattcattaa aataattcta atttaaaaaa
     6421 taattctatc caaataatag atatatagga ctatgttata atataaaaaa atttatataa
     6481 aagttaataa ctatacaaga ttgataaaga aaaagtcaaa atagataatt gattagcaaa
     6541 atagatataa ttataatgaa gttaaatcta gcaatattct cctaaaatta aattacattt
     6601 atttaattaa atataatttg acaatggaca aaaaagtgag taaaatataa ataaaataaa
     6661 aataacaggt tcggataaag aaaaaggttt cttaacctca agcataaagt atattatcta
     6721 agttatttga gattaagaga taaatccaat cttaggtact gaggaggaaa aaatgcttga
     6781 tataaaaaga ataagagaaa atttagattg tataaaaaaa gcaatggaaa gaaggggcga
     6841 aaaagacttt aaccttgatg aagtagttaa gttagatgat gaaagaagaa agattcttca
     6901 agaagttgaa gttatgaaaa atgaattaaa tacagcatct aaaaatatac caaatcttat
     6961 aaaagaaggt aaagatgtag aaaatgaaaa gattaaacta aaagagttat ctgataaaat
     7021 taaggtaata gaccaaaatc ttaaagaagt agaagataag atggaatacc tattaatgag
     7081 aataccaaat gtaccacatc cagaagtacc acaaggtgaa actgatgaag ataatgttga
     7141 agtaagaact tggggaaaga ctactacctt tgattttgaa tctaaggctc attgggaaat
     7201 tggaacagaa ttaggtatac ttgattttga aacagctagt aaaataactg gttcaagatt
     7261 tactctttac aaaggattag gtgctagatt agagagagca ttattaaatt tttacttaga
     7321 cacgaataca aaagtaaatg gatatacaga agttattcca ccatttatgg caaatagaaa
     7381 tagtttttta ggtacaggac agttacctaa gtttgaagaa gatatgttta aaatagaagg
     7441 tatggactat tttatgattc caacatcaga agttccttta actaatatac atgctaatga
     7501 aatacttaaa tttgaacaat taccgataaa ttatacagct tatactccat gttttaggtc
     7561 agaagctggt tctgctggaa gagatacaag aggtttagta agacaacatc agtttaacaa
     7621 agtagaaatg gttaaaatag ttgcaccaga agaatcttac aatgagttag aaaagcttac
     7681 taacaatgcg gaaactatgc tacaattatt gaatctgcct tatagggtag taaagatatg
     7741 tacaggtgat ttaggattta cggcttcttt taaatatgat gtagaagttt ggatgccaag
     7801 ttacaatagg tatgttgaga tttcatcttg ttcaaactgc gaagatttcc aagctagaag
     7861 agcaggaata agatttaaaa gagataaaga ttctaaagct gaatatgtac acacattaaa
     7921 tggctctggg ttagctattg gaagaagtgt tgcagctata ttagaaaatt atcaacaaga
     7981 agatggttct gtggttgttc ctgaagtttt aagaccatat atgggagttt ctgttattaa
     8041 gtaagagtta aattatgtat ttttaagcaa tacaataata tagaggtaat aaaaaataat
     8101 taatataaaa gtgatacaat aatatagaag taataaaaaa atagttaata taaaagtgat
     8161 acaataatat agaagtaata aaaaaaaata attaatataa aaatgtgtac aaactaatga
     8221 atattgatat agtaagctat catatgaaag agtatgtaca catttttttt actaattttt
     8281 cacaatatga acataaataa tttacaggaa aggaatcttt tatgaaaatt caaaatactg
     8341 agtggggata tattgaatgg aaacatactt atgatgaaaa taatccaaaa caagctatga
     8401 atatatacat tgcagtaact atgcctggta agaaacattt taatcatgtt cattatggtc
     8461 aagagcagat gatatatatt ttagagggag agggtttgta tattataaat ggagtttgga
     8521 agccatttta tcaaggtatg attttttata tagaatctgg tagcacacat gaaactataa
     8581 atacaggtga tagagaaata aaagaactta ttgtttcaaa taatgtagat gatgtaggag
     8641 agagtgaagt tatagatatt aatcctaata attatttaaa gaagaccttg ataaattata
     8701 gtgaaagtac attaaatttg tatgcagcag tagaatcaat tcgtggtcaa tttatagacc
     8761 cgtttaaaat tccattaatt atatatgatg attcatggaa tatagtttta aaaaatcctt
     8821 attttccact tttttgtttt gaaaaatgta atcctatgaa atttcctcaa aattgtgatt
     8881 gtatgaatca aaaaagtagc aatcaatttg tatgtgaata tgggataact atatataata
     8941 taccaatact gtacaaaagc aatagcatag gtgttataag aggagggtat gtactattat
     9001 ctgatttgaa tttagataca gagcataata atttatatga tattccagag ggagctgcta
     9061 gaagtataaa acgcctcttg aaacaaatat ctaaaaatat aataaatttt tgctctttta
     9121 atgatataag aaaggattta caagaaaaag agaagactat agcaagaaca tatcattatg
     9181 gagagcaact tgaaatgaat ttaaaagtag ctcaagatat ggttactaat ttaagaataa
     9241 atcatcactt tttatttaat acattaaatt caatggcaag catagcacta gatgatggta
     9301 gttatgattt gtatagtgca ataatagatt tatcaagaat gtttagatat acaatgaggt
     9361 ctgatttaag atttgtagaa ttagaatctg aaatattata cattaaaaat tatttgaatt
     9421 tacagaaatt acgttatgga gatgcactta aagtaaaata tcttattcca gagaagttat
     9481 ataacctttc tgtgcctttt aactttattc aacctattgt agagaatgca tttacacatg
     9541 gatttagaga tattgacaca gaaaagcgaa ttgaaataat tgcaagatta gattctcagt
     9601 atgctattat agagattcat aataatggaa ctatcttaga tggaaataat atagacaaaa
     9661 taaaggcagg tattcgtagt aataatggtc atggtttgtc tttaatatat acaaaattca
     9721 catctgctta tggaaataat tttgatatgg atataaagtc gagtgataat gaaggaactt
     9781 acataatgat taaaattcct attgaaaatt ataaggagta tgtatagaac ttgtgaaaaa
     9841 ttaataagtt ttataaatgt taagaaatat attagatgtt tttatgttgt tttatatatc
     9901 ttactttttt atattattaa gctaaaaggg aggtattctc atgagaagag cactaataat
     9961 agatgatgaa gaagctgttc taaaaataat aacacatttt atagaaatga aagatatgcc
    10021 aataaaaatt gttggtaaag caacatctgg tgatgaagca gtagataaaa tcattggttt
    10081 agagccagac atagttttta tagatattca aatgccaata tacaacgggt tagaagtaat
    10141 agaaaaaaca tctcatttat ctaaaaaaat aaactttgta gtaataactg catttaacta
    10201 ttttgaatat gctcaaaaag ctttgagatt aaatgtaaaa gatatactcc ttaaaccatt
    10261 ggatatgaaa gaatttacta agtctgtaga aaaaattatt ggatatcaat ataccaataa
    10321 tgatttatta aatgagatac tggaatatat aaatctaaac tatagcaatg acttaaagtt
    10381 aaatgattgt gctagattat ttttaaccaa tccatctaat atatctagga tttttaaaag
    10441 taatttaaat acaactttta tatcatatct aaatcatata agaatagaaa aatctattga
    10501 gttacttgaa aatactacaa aaagtataaa tgagattgca gaaatagttg gatataatag
    10561 cctaaataac ttttataaaa actttaagat agaaaaagga atgactccaa aagtttataa
    10621 actgaacact aaaaattgaa attgataaat aaaaagtcaa tatagataat tgtttgagtg
    10681 tgtctgaata agtatacttt aattatgata aaaattaaag cgctttaaac atatttaata
    10741 atattaaacc ttataaaagc tgtacctatt tatataaaaa aatatatata aataaaaaga
    10801 aaaagatata caaaataaaa aaagtgaatt aaatactgtt tcaaaaagac agaattttca
    10861 tttaatttac tgagagttta tatttcttaa aggaaggtaa ctttataatg gaggtaattt
    10921 aatatgtcag acaaagtgaa tatgaaaaat attatctgta ttgcaggcgc ttatctagca
    10981 acagcaattg gttctgggtt tgctactggt caagaaattc tacaattttt tgcctcacaa
    11041 gggtatatgg gtttaattgg agcattaata tcaatggtat tgttttcatt tcttggtgct
    11101 gaagttataa ctagaggtag agaattaaaa cttaaagaac caacaagaat ttacactttt
    11161 tattgtggga agattttagg aaaattttac gaatggttta gtccaatatt tttatttggg
    11221 attcttatag taatgatttc aggtgcaggc tcaactttaa ctgaatacta tggtataaat
    11281 ccttacttag gaagagtatt gatggctgtt gctactttaa ttacagtgtc tatgggttta
    11341 gaaaaattag taagcatact tggacgtatt ggaccagtga tagcagtatt tacaattgct
    11401 gttggattaa taagcttgtt taagcatttt gatggtttat ctatggttgg agaagctatg
    11461 aaaaatattg aagttacaaa agcatcagaa agtccaatcg tttctggtgt aatatataat
    11521 acattaaata ttattgtaat gattgttttt ttaacaggaa tgggagcttc tattgaaagt
    11581 aaaaaggatg ctttttgggg aggtttatta ggtggaatag tgtttatgac tgctggtata
    11641 gttatgtatt tggctatgat ttcagatata ggaaatttgt atatgaaaga aataccatca
    11701 ctttatttag cagataatat atctcctatt gtaggtgtat gtttttcagt tgcattaata
    11761 ttaggtatct acacaacagc tgttccactt ttatggtctg taaccaatag aattgttgaa
    11821 gatgaacatc ctaaatttaa attggtaaca acagtaatag ctattttggc ttgtatagga
    11881 ggttttttac cgtttggtaa actagtaaac attttatatc catatacagg ttatatgggg
    11941 cttttaattt tagtctgtat ggtgtataaa gcaattacat gtagaaaaaa atcaacacaa
    12001 agtcaggaat agagccactt attaatagtt tttatttaaa gaaatttttt atataatccg
    12061 aatttaaaaa gtcaaaatag ttaaataaat tgtaaaatat gataatatat ttaattaaaa
    12121 taatatagta aaatataaat ataaactaaa attaaattta taaaaaatat ctttataaag
    12181 attattaact tatataattt gtagttaaat tataaaaaat aaaaaaataa aattttggag
    12241 aggtgttagt atgcatgaac ttattttaat ctcagaaaag tataaagaag atattttaga
    12301 tttttttaca gatattcata tgcaccccga attaagtttt aaagaattta ggactacaaa
    12361 agctataaaa gatttattag tgagtttaga catagaaata ttagatttag gaatggaaac
    12421 aggagttgtt ggattattaa aagggaagta tgatggtccc acagtagcac taagaggaga
    12481 tattgatgca ttgccaatat atgaagaggt tgatattaag tataaatcca gatatgatgg
    12541 tataatgcat gcatgtgggc atgatataca cacgtcttgc cttgtaggat gtgcatatgt
    12601 attgtctcat attagagata gtcttcatgg aaatgtaaag tttatatttc aaccagccga
    12661 agaagtcaat aaaggtgcga agatgctagt ggaacgagga gtaatggaaa atccaaaagt
    12721 tgatgctata tttggacttc ataatcatcc agatatacct tgtggaaaaa taggtgttaa
    12781 gttaggtggg ttaatggcag cagtagacac tattaagata gaagtaaatg gatttggagg
    12841 tcacggaggt atacccaaca gaacaataga ccctatagta gcatcaagtg caattataat
    12901 gggtattcaa accatagtaa gcagaaacat aagtccatta gaatcagctg ttatatcaat
    12961 aggtactata aatggaggga ctgcaaataa tgtaatttca gaaaaggtag atatgacagg
    13021 cacatgtaga agctttagta atgaagtacg aaagaaaata tcagaaaatt tagaaaatat
    13081 agtttgtgag atagctcgtg gatatcaagc aactgcaaag ctagattatt tatttgattt
    13141 accagctgtt ataaatagta aagagatgta cgcaatagct tgtaagtctg tgtgtgattt
    13201 gtattcagaa gatgctatag ttgatccaat accttctaca ggaggggaag atttttctat
    13261 attcatggaa aaagccccag gattttttta ctggttaggg gtaggcaaca aagaacaaga
    13321 ttgtatatat cagtggcata atcctaaatt taaagctgat aaaaattcta tattggtagg
    13381 tacaaatgta ctatgtcagt ctgttataaa ttatatggat aaattaaaaa ataaaattta
    13441 agatagagca ttctggagat aaagtttatg agggggtatt agtttgagga aaattaattc
    13501 acaggaaaaa aacaaagata gtggattatt gatgagggca ctaaatgttg tagagagagc
    13561 aggaaataaa cttccagacc cagtaaccat atttttatta ctatgtataa ttgttgtaat
    13621 attgtcagca gttatatcta atttaggagt agaagaaata catccttcta caaaagaagt
    13681 tgtaaaggta gtaaatctac tagagaaaga gcagattcaa tcatatttag gtagcatagt
    13741 tacaaacttt cagtcatttg ctcctttagg attagtactg gttacaatgc ttggagcagg
    13801 tgttgctgag aaatctggat ttatggaagt gttaatgaaa aagggtataa gtaaagttcc
    13861 acaaaaactt gtaactgtag caatcgtatt tgcaggtatg ttgtcacata cagcagcaga
    13921 tgtaggattt ataatattac caccacttgc agcacttgtg tttttaggaa ttggaagaca
    13981 tcctcttgta ggtatgtttg cagcttttgc aggtgttgca gggggatttg cagcaaatgt
    14041 tatgcttagt actacagatg tattgttagc tggatttaca ataccagcag ctcaaatgat
    14101 ggacccatct taccaaggca atccagcaat gaatctttat tttgctttta tatcagcgat
    14161 agttttaact tttgcaggag catttgtaac tgaaaaattt atagctcctc gttttacaaa
    14221 atataatgat tcaacaaatg ataaggatat acaggaattg agtgaacttg aaaataaggg
    14281 tataaaatac gctttattat cattgttagt tgtagtagta gtgatagttg ccttatgtat
    14341 aggtgacaat gcatttatga aagatccaga gactggttct atactatcta gtaatgcacc
    14401 tttaatgaaa ggtatagttc ctataatcac tattatattt ttaactccag gattagtgta
    14461 tggaaaagta agtaagaaga taaaaagtga caaagattta gtatctatga tgggtagtag
    14521 tatgagtgat atgggtggat atatagtcct agcatttata gcatcccagt ttattaattt
    14581 atttaatctt agtaacttag gaacaatttt atcaataaca ggagcaaaat tactagcaga
    14641 gtcgggaata cctagctatg gattgataat aggatttata ttgctatctg gatttatcaa
    14701 tttatttgta ggaagtgctt ctgcaaaatg ggcgatttta gcacctatat ttgttcccat
    14761 gtttatgcta ctagacttta atccagcatt aactcaaata gcttatcgta ttggagatgc
    14821 ttcaacaaat ccaataagtc cactttttcc gtattttcca gttatattgg cctttgccag
    14881 aagatatgat aaagatatag gtataggtac tgtcatatcg aatatgattc catactcagt
    14941 ggtatttaca ttaatagaaa taataatatt gttactattc atgggtattg gcataccatt
    15001 aggacctggt ggaggaatat cttacgtttt atagaccgtt ataataaatt tatcaatgaa
    15061 gattaaacta ataaaatata ttctttaatt aagaggagga ttattatgtt aaaaacaaca
    15121 aaaatttcag acccagagtt atacaagatt gtagctgatg agttggttag acaagaacac
    15181 aatattgaga tgatagcttc tgaaagtaca gcaccaacag aagtacttga attaagtgga
    15241 tgtgtattta caaataaaac agaagaaggc tatccagggg ctcgttttca agcaggttct
    15301 gaagaagcag ataaacttga aaccctagca ataaaacgtg caaaagaagt atttggagca
    15361 gaacatgtaa acgtacaacc gtattcaggt tctacagcta actattgtgt atattcatca
    15421 atattaaaac caaatgacac tgttttaagt atgcgtcttg accaaggtgg acacttgaca
    15481 catggtagcg cagttaattt tttacatgac atttataaat atgaatttta tggggtagac
    15541 ccaaatactg gacgtataga ttatgatgct cttgaagcaa aggcaaaaga atgtagacca
    15601 aaacttataa ttgcaggggc aagttcatat ccaagattaa tagattatga aagaatatca
    15661 aaggttgcaa aagaagtagg agcttacttt atggtagata tggcacatgt tgcaggatta
    15721 gtcgcagcga aagtaatacc tagtcctgta ccttatgcag attttgtttc ttcatctacg
    15781 acaaagactt tctgtggacc aagaagtggt attgtacttt gtaaagcaga acatgcaaag
    15841 aaactcgata aaggtgtttt tccaggaaca ttaggttcta tacatcttaa tacagttgca
    15901 gcaaaagcct tttcactatt atatttaagt acagataaat ttaaaaagat aatggagcaa
    15961 gttgtagtaa atgctcagac tctagcttct gaactgattt cacatggttt tagtattgta
    16021 agtggaggta ctgataatca tatagtaatg gttgacttaa gaagtaagaa tcttacagga
    16081 aaacaatttg aaaaagctct tgaatatgta ggaataacag ttaataaaaa tgttatacct
    16141 gacgacccac aatcaccatt tgtaactagt ggtgttcgta taggtcttac atcaatatct
    16201 caaagaggtc tgaaagaaaa agaagttata cagatagcag ggataatgaa taaggtagca
    16261 gaaaatattg ataataaaga agtattagat gaatgtaaag cagaggcaca agaacttata
    16321 tctaagtttc cattatatcc agaagggtat tttgaagatt aaatattttg atttgtatag
    16381 ctcacaattt ataaagcctg taacataaaa tttaataata tataaccact ataaggtgtt
    16441 gattaatcaa caccttattt tttttgaaaa gtaatataca agctatcata agcatataat
    16501 tccttataga taattaacaa gggggataaa gttatgaggt attataataa acctaccaaa
    16561 gaagtattaa aatacttaaa aacaaatcca gaaattggac ttgatgataa tgaggtagaa
    16621 gaaaggaagc ttagatatgg attaaatgaa tttactataa aagaaggtag aacattttgg
    16681 gacgagttgg gagaaagttt gacagaacct atgatattaa ttctcatagg agcagcagta
    16741 ataagttctt ttgtgggaga attacatgac gcattaggta ttttaggggc tatttttatt
    16801 ggaatttcta taggcataat aactgaagga aaatctaaaa aagcagctca tgccctgtca
    16861 aaattaacag aaaatataga agtaaaggtg cttagaaatg ggaagataat taaaatatca
    16921 aaaaatgatt tagtaccagg agatattgta tatatagaaa ctggggatat gataccagca
    16981 gatggaagac ttatacagtc tataaatttg aaacttagag aagatatgct aacaggagaa
    17041 tctgatgatg tagctaagaa tgctgatgct gtattagata tggaagtagt ttattctaaa
    17101 acagaaataa tcgaacagga tgcaatacct gcaaagcaag tcaatatggt atttggaggg
    17161 actcttgtag catatggtag gggcataatg gttgtcactc atactggtga taagacagag
    17221 atgggtaaga tagcacagaa tttatcaaat gaagaccagc aaactccact tcaaattaaa
    17281 ttagggaagt tgggtgctaa aatagcagga atatcaggca taatagctac tttattgtgt
    17341 atgtttatga ttatacagat gcagagaaaa ggtatgttaa ttttagatac aagcagtata
    17401 ttatctttct tacaatcatt agaacctgct aaaaatgcat atatggtttg tattgcatta
    17461 atagttgcaa ctgttccaga aggtttgcca actatgataa atattacctt agctataaca
    17521 atgcaaaaga tggcaaagat aaatgcatta gtaacaaaga aagaagcctg tgaaactata
    17581 ggttctgttt ctgtaatatg ttccgacaaa acagggactt taacacaaaa caaaatgatg
    17641 gtagaggtag catatgttga tggtaaatat ataagtggag gagagtatca aagtaatagc
    17701 tattttgaac aaaactgtat agtaaattca actgcagata tagaaaaaga agataattca
    17761 tttaaatata taggaagcgc aacagagtgt gcattacttt tatatcataa tgataagaac
    17821 tataatgaaa tgagaaaaca aacgtatttg atatcacaaa taccatttag ttcagaagaa
    17881 aagaagatgt caacattaat tcgtcaagag gattcagata tattactttc aaaaggtgct
    17941 ccagaagtat tattaaaaaa atgttcttat gtacaacaag gaaaaaatat tgttccaata
    18001 actccaaaag tagaaaaaag tattttagat gagattaaga agttacaaat taaatctatg
    18061 agaacattag gatttgctta taaaaaaatg agtaattcta aaacagaagt tgcaatgact
    18121 tcagaaggtg aattgaattt aataggaaat tcaagaagtt atatgaagga agataattta
    18181 gtttttagtg gatttgtagg aatagtggac ccattgagag aaggggtcaa agattccatt
    18241 gataaagcat ttaatgcagg agtagatgta aaaatgctta caggagataa tataaataca
    18301 gcaacagcta ttggaaatga attaggatta ttaaatgatg ggaaaaaggc agttgaagca
    18361 acatatatag atgtattgac agataaagaa ttgagagaag aaatcaaagg aatatctatt
    18421 gttgcaagaa gtaaaccaga tacaaaaatg agaatagttt cagcacttca aaaaagtggc
    18481 gaagttgtag ctgtaacagg tgatggtata aatgatgccc cagcacttag tcaagcagat
    18541 gttggaattg caatgggtat ttcaggaaca gaagtatcta aaaatgcagc agatataata
    18601 ttgactgatg atagctttag tactatagta gagggaataa aatggggaag aggtatatat
    18661 gagaactttc aaagatttat acagtttcag cttactgtaa atatagtagc atttataatt
    18721 gctataatat ctcaacttac tggtaaggat atgccattta ctacaataca attattatgg
    18781 gtaaatataa taatggatgg tcctccagcc ctagcattag gattagaacc tgttagagat
    18841 tatgtattga aaagaaaacc aataaataga cattctggaa taatagctag gtctatgttt
    18901 gtaaatatta ttataaatgc aattcttata attacaattg tatttactca atcagctttt
    18961 aatatattgg gagctacatc agaagaacaa ggtactgtta tattttcttt atttgcattc
    19021 agtgcccttt ttaatgcatt aaattgtaga gagtttggtt taaatagtac aataccaaat
    19081 ttctttaaaa ataaactggc attgcaaata atagtagtta cagggataat tcaaataata
    19141 tttacacaag tgttccagag tttctttaat tctgtttctt tggactttga tatgtggata
    19201 aagataatac tatttgcatc cactatccta ttgtcaaatg aatttgtaaa gctaattctt
    19261 agaacaatga aaaatagtag aactatgaac tttaatagta aaaattaatt cttatgaaac
    19321 cgtaaagtac tatatattgt aactttgcgg tttttgtttg tttaatgttg ttttatatta
    19381 ccattttcat atttaatttt ttattaatct gaacacaatc ttccattgta attgcttcat
    19441 ctgtgtcaac acattcaaag tcaatatcta atttttgtaa tattttatat gcctcttttt
    19501 gcaaaggagt atcaaattta ataggtgatt ttgtgtaaat atcactgata aaaaacatga
    19561 tttatttcat tcctttccat ttaaaatctt atagttatag tgtatcataa ggttataaaa
    19621 tatagataaa tatagtataa atttaaaata tgtacagaca aaacaaaaaa atcatattct
    19681 aagtaatact tgggaaaaat gatattatca taataaataa tctttgtaaa aacttatata
    19741 gaatctatta aacagacact aagccataaa aactttacta aatataaaat tcgtatctaa
    19801 atagatatat agaataatat tttactgaag tagagtgatt tttaagaatt ttatatataa
    19861 attatgttat cataaataaa gatatagatt ataaaatttg ttaataaaat aaagggcagg
    19921 gaggtaagtt tcatgttttc caaaatccta gtcaaaacat ttatcagaga tagcgaaaac
    19981 gttcaaaata cagatgttag aaataagtat ggttatgtag ctggtgtagt aggtatatta
    20041 tccaatttac ttttatttgt gataaaggta ttcataggaa tgctcacatc tagtatagct
    20101 ataatggctg atgcatttaa taatctttct gatatggcat cttcagcaat aactatgata
    20161 ggttttaaat tagcaagtaa gccagctgat aaagaacacc cttttggtca tggaagaata
    20221 gagtatttat cagcattaat agtagcattt atggtgatgt tggttggact tcaatttgta
    20281 aagtcatcta tagaaaggat agtaaatcca attcctgtaa aatttgaagt aataccactt
    20341 atacttttaa ttgcatctat aatgattaaa atctggttga gtcgttttaa taaatttatg
    20401 ggaaataaaa ttgattcttc agccttaaaa gcagtttcac ttgatgcttt aggagatgta
    20461 tttacttcaa gttgtgtagt tatatcattt attgtagcta gatttactaa ttttcccata
    20521 gatggatatg ttggtatcgt agtatcatta gtgatacttt atgctggttt ctctcttgta
    20581 aaagatacta taaatcctct tttaggggaa gcaccggatg aagaaatggt aaattctatt
    20641 atagagctat tgttatctta taaatatata ataggtacac atgatttaat tattcataac
    20701 tatggagttg gtagatgtat tgcatctata catgcagaaa ttccatccaa catagatata
    20761 atggaaatac atgaaattat agatactgca gagagagaaa tatctgaaaa attagatata
    20821 tatctagtaa ttcacatgga cccaatatgt cttgaagata aagaagttat gtcagccaaa
    20881 aaagaacttg aagaaatact taagaaaaat agtcttgtaa aatctatgca tgattttaga
    20941 atagttggaa aaggaagcaa gaagaattta atatttgata tagtagttaa tccttccgaa
    21001 ttttccaaaa acatgtcaga agatgactta aaagaagata taacaaaatt agttaaggag
    21061 ataaatcctg aatataattg tgtaattgtt gtagataagg attttattta attattaatt
    21121 aatctcatca taaggtaaaa aatgtaaaaa ggatagacaa tagtatagag gcataatata
    21181 atagaagtat ataattgtat ttttaatata aataaagcaa ttttaattgt ttttatgaaa
    21241 tattatagag atgttgaagt atattctatt attgggcacc ttatggatat actgagtcag
    21301 tggtgcaacc ggctatgaat ataaatttat ttattttcat agcttttttt gtataatttt
    21361 ttagtaaaaa ttactttata tacgatatta atggaagatt agattataaa ttataggtaa
    21421 cctaaagggg tgagatttac atgaagaaag gaaatagaaa ggcattatta attagtttaa
    21481 ttatgatttt aagtatggtg gtgtctacaa tatatccaac tgtatcttat gcttcggaat
    21541 taggagagaa tagtcagatt caaagtggtt caactaattc atcaactgga gaggagaagg
    21601 aaagcgacaa taaaaagcca gaacagactc cagagaaaga taaggcaaca gataataaaa
    21661 aaccagaaca gaccccagag gaagaaaaac caacagataa taaaaaacca gaacagaccc
    21721 cagaagaaga taagtcaaca gataataaaa agccagagca aactccagaa ggagaaaagc
    21781 caatagataa taaaaagcca gagcagatac cagaagaaga taagtcaaca gataataaaa
    21841 agtcagaaca agctttagaa gatgaaaaac cactagacaa taaaaataca gaaaaaactc
    21901 cagaggaaga taatctatta gaaaatgaaa atttattgaa agttttagaa gaagaactta
    21961 atgaagaaaa tgaagactat ggatttgttg taaaaattaa taacaataca atagaaacgg
    22021 aatcaatgaa aaaaatatca tttaatttaa cttatactcc aacatcaaaa ggaatacaag
    22081 caggagattc aataactttt aaggtgccag atgtattcaa taaagttaat ttagattata
    22141 caagtgaatg ctttgataaa acagaaagta atggagagta tacacttaca tttagagaat
    22201 tacctaatgg ccaaagtgta atgcaaggta aaataggttt ggaagcatat gttaaaaagg
    22261 ttgatgaaga tactaatgca aaaatacata ttgaaactac tggaaaaata gaaagtggaa
    22321 gtggagatat agatgtagaa ataaaacctg gagataaaac ggatgttcca gatgctaaag
    22381 gaacacttaa aaagcttgtt gaaggaaaaa aatcaactac tgtatttatg ccagttaaaa
    22441 ataaagatat aaattacagt atacaagtaa atgaaaagca ggaagagtta aaagatatta
    22501 ttttgtatga tgagcttcct gaaggattga cattgataaa tggttctgta agtgtagtaa
    22561 caagtgatgg aaaagaagtt agtgatttta atattgaaca gagtaaaaat tctatttcag
    22621 ttaatcttgg aaatatagat aaatcgtata ctgttaagta taaggctaga atcagtgaca
    22681 aaaatgcaaa acatggtaat aaatataaga atgtagctag gattgaatct gatggtaaga
    22741 agatacaaga agatgatgct actgtaagta tatttgatag aggagatgat tatcttctta
    22801 ctaaaggaca ttcaggagca acaaatatta ctcaagttgg tcaagtaata aactatcaga
    22861 tttcaataaa tgatgataaa tcaccaataa gtaatgttgt tataacagat aatataccag
    22921 aaggcatgag attaactact tcaggagaag ctgggcatga ttttagagtt gtagaaattc
    22981 caatgaatgg gagctggact ccttggagta aagaaaaaat tgccaataat atttcatata
    23041 aagtagaaga aaaaagaaat gaaagtgggc aagtagataa agttataact ggatttacaa
    23101 ttaatctcag taaagaagaa gtggaatcaa agttttttat agcttataca ttaaaggtaa
    23161 ttagtattga agatagctat ataaatagag ctgttcttga tgcaaataat agtgaaattg
    23221 ataaaaatga tgagataaac tttaagaaaa attctggatt aataagcgca aaaaaagaag
    23281 ttgataaaaa agttttaaat agtagtgata accagattgt taaatacaaa atcaatatgt
    23341 caacttatgg ggtttatgat gcaggacaag taaatctttt agatgaagta aactcagctc
    23401 tagaaatatc taatataaaa tattctgata atcttgaact taaaaaagaa gctggagatg
    23461 gaaaaaatac aataagatta gtaaataaat acgaatttaa acagataaaa gaaggggaac
    23521 ctgtgcaaag ttgggttaca tttgatgcag acttcacaaa tgtaaaagtt ggggagacta
    23581 tacgaaatgt ggctcagatt aatggttcaa gtcctccagg agtagagact actaagcaag
    23641 gttatgcttt tgaagctaaa aaagtggatg ctttagataa aaatgtactt tcaggtgcta
    23701 agttcaattt agaagatgca tttggaaata tagtagttaa ggatttagtt agtgatgaag
    23761 atggtataat tcaatctagt ataaaaaaac caggaacata ttatttagtg gagataatgg
    23821 ctccaagtgg atatgaaaaa ctgaaggata aaattaaggt tgaaattggt aataaagata
    23881 ttggtagaat agtggatatt ggaaatatag aaaacataag acaagaaaat ccaccagtaa
    23941 atccaccagc accaccaaat acagatgaac caatagtaaa tccaccagta ccaccaagca
    24001 cagataaacc aaggaaacca tcaagttcat ctgatacaga ggatactata gttataaatc
    24061 caccaatacc accatcagaa gatataataa atccgccaat accagaggta ttgaatccgc
    24121 cagtaccacc atcagaagag atgatagaaa ctcctgttaa acagattatt ccaataccag
    24181 aagtagtaaa gccatcagtg tcagaagaaa aaaataataa agttaaagat gatactttgg
    24241 taaatccacc agtaccacca aaaacagggg atagtactac aattattgga gaaatacttt
    24301 tggttatagg agctattgta ggacttatcg tattaagaag aaataaaaat acaaattaga
    24361 ccctaacatt ataaaaaata taagttatat taaaaaatat cttctaaaac aatatttaat
    24421 aatgaaaata ttgttagaag atattttttt ttgaagattt atgtaaaaaa ataataactt
    24481 tttagaaaaa agttccaaag ggatatagac aattaaaaag atataagcta taatatagat
    24541 ataaaattaa atgaggcaaa actagggaaa cctagtcacg caaagctata ggggctaaag
    24601 tttagtaaac catgccagcc agttgccgaa aagagtaaaa atttcttttt gtatatacaa
    24661 agatactctt gggtatcttt tttattttga aatttattac tcccggccta actcaaagga
    24721 gggaataata tgagaccaag taaaaaatta ttaatagcta taatatcaat attcttaata
    24781 agttcagttc cagtaagtgc acatgcagat agtactacta tacaacaaaa taaagacaca
    24841 cttagtcaaa tagtagtttt tccaactgga aattacgata aaaacgaagc taatgctatg
    24901 gtaaatagat tagctaatat agatggaaag tatttaaatg cattaaagca aaataactta
    24961 aaaataaaat tattaagtgg aaagttaaca gatgaaaaag aatatgctta tttaaaaggt
    25021 gtagttccta agggatggga aggtactgga aaaacttggg atgatgttcc aggtttaggt
    25081 ggaagtacag tagctcttag aataggattt agtaacaaag gtaaagggca tgatgcaata
    25141 aatttagaat tacatgaaac agcacatgca atagaccata tagtattaaa tgatatatct
    25201 aaatcagcac aattcaaaca aatatttgct aaagaaggtc gttctttagg taatgtaaac
    25261 tacttaggtg tatatccaga agaatttttt gcagaatcat ttgcatatta ctatttaaat
    25321 caagatacaa atagtaagtt aaaatcagct tgtccacaaa cttatagctt tttgcaaaat
    25381 ttagctaaat agagttttaa taaatttaaa ataaatataa ataaagagat gctattataa
    25441 tagcatctct tttatattgc gtttaaatct aataaatttt gtcttatgta taactatgat
    25501 agattatcaa ttactactcc ttatacaagg cttcaacgtg tttattatgc atttgagtaa
    25561 ttatcgtagg tataatagaa attattgaac caattactat caataaaatt cctataacca
    25621 tgtttatagg gataatttct ttaagtatta ataatgctag tattggagat attactggtt
    25681 taaagaagaa tactaaagat gtaagactag tagatgtagc ttccattgcc ataaagtaaa
    25741 gcgcataacc aacacctgta acaaatacga atacataaat cataatgggc atattgtgta
    25801 aggtatatcc actaaaaata gggatatttg caaatacatg aagcttattt ttatttaata
    25861 tatctgcgat aaaattaatt ttagtgagta aaaccaatat caacatttcc aaactaccaa
    25921 atataaagct aaagcaggtt acaactattc caccaaattt taaggttttt cttttaccaa
    25981 atacagtata cattgaaaaa ataatagcag aagataatgt taagaatatt ccactaagag
    26041 ttagttttgt atgcaatgga tttattataa ctataattcc aagaacttct aatataagtg
    26101 aaattacatt gtgcctatat attttttcct tcaaaattaa gtaagctaaa agcattacaa
    26161 agactggatt acaactgaac aaaacagcaa ctacagatgc ctttgtgttt agaacagcaa
    26221 gttgatacaa tgacatactt actactacac acataaaacc taaaaatgca aagtatttta
    26281 agtctgattt tgtaatagaa agactaagag ctcttaatct ttttacagca aaaggtagta
    26341 agactaaacc gccaacaaaa aatcttgata aagttatttg taagggatta aagtcattag
    26401 tgacagtttt tagactaatt tccattgaac taaaaaataa ggtagtcagt attatataaa
    26461 cataaccttt tttcaagtca aacacctcct tgtaatttat attagtacta tagataagaa
    26521 tattcaagca tattggaata atatggtatg tataaaatat agtacataaa attataaact
    26581 accttaatat agaatgtaag tattctatac taaggtagtt aattatttga attactttga
    26641 tttagttatt ttaaattata taatttggct aatttttcaa atgctggtaa agaactttta
    26701 actttatcat aagatacaca atatgatact ctaaaatgac ctggacaacc aaaagaagaa
    26761 cctggtacta ataataaatt aaattgtttt gcatcattgc agaatttttt atcatcttca
    26821 attggagctt ttgggaacaa atagaatgta ccattaggtt taacacaaga atatcccata
    26881 tcgattaaac tattatatag aaggtcaaaa ttctttttat aaatatttac atcaacttct
    26941 gcatctaaac ttcttgcaat aaccctttga aaaagagaag gagcatttac aaatccaagt
    27001 attctatttg caacatttaa tgaagacata acatcatcaa aatcatccat ttgcccatta
    27061 gcaacaatat atcctatacg ttcaccaggt agagataatg atttactata agagtatcct
    27121 ataaatgaat ttctatagta ttttagtaca caaggaactt tggcaccatc ataaattatt
    27181 tctctatatg gctcatcaga aattaggtat atgcttgtat taaattcttt ttgttttgaa
    27241 tccaataatt ctccaagatt ttttaataat tcttcagaat atatgacacc agtaggatta
    27301 tttggagtgt ttattattaa agctcttgtt tttggagtaa tagcattttt tagagcatct
    27361 aaatctggtt caaaagtctc tatatttgta ggaacttcta ttaattttcc atcatagttt
    27421 tctgtataat ttttatactc accaaaatac ggtgcaaaag caataacttc atcaccagga
    27481 tttaaaagag tttttaaaat aatatttaga ccaccagcag caccacaagt cataattaaa
    27541 ttttctcttg taagatttaa tccatctttt ttatttatgt gttcagcaat agcatctctt
    27601 acatcctcat atcctgagtt gttcatatat ccatgaacta aatttggaga ttcttcattt
    27661 aaaatatcat ttataactgc tttaatagtc tctggaggtt caacacttgg atttcctata
    27721 ctaaaatcaa aaacattttc ctcaccataa atatcagaaa gtttctttcc ttcttcaaac
    27781 atagctctta taacagaact atttgcaact aaagtttgca ttttattaga tatcatatgt
    27841 aacactcctt tttatagatt tatattgctt atgtatatat taccatattt ttactgaatt
    27901 tagacaattt tcgaaaaatt acttgtttga aaatataaac ttttatataa aatatattta
    27961 tgtacagtac atattaaaaa ttccaatttc taattttatc atgattattt tatataatag
    28021 ttttttaaag aattaataaa acatagattt agagaataaa atattcttga ctatattaat
    28081 tgtttaatat aatatagttg atatagtcaa acatattata attatagaag ggaaatttaa
    28141 gatggatttt aaaaatttac agtatgaaag tttgtcatat attatttgta acttgcaaaa
    28201 aaactttaaa ctttattgtg aaaaatgttt aaaaccatat aaacttacga atggtctata
    28261 tttctattta atttatatta ataaaaatag gaattgttct ttgaatgatg tttctacaga
    28321 atttgaagtt gataaagctc atacaacaag aactatatct aggttagaac aagatggata
    28381 catagaaaaa atccaaaacc ctaatgatag tagagctttt cagttgagag taacagataa
    28441 gggtgaggaa gtattagggg atataaaaaa catattttca aagtgggata atcacataaa
    28501 aaaagagttc tcggatacag aatataaaga actggtaaag aatttacatg tggtaaagga
    28561 tataaaaaca gctgtggagg aagaatagga tgtattgtaa tttattaaaa ccaattaaaa
    28621 ttggaaattt ggaattaaaa aatagagtat cttttgcacc tacaagcatg ggtcttaaat
    28681 tggaagaaaa aattaaaaag ttttctgata ttgctaagtc aggagtagct ctgattactc
    28741 taggagatgt atctattaga cctagttttc ataaggtagc tataagccta tcggatgaag
    28801 atggagtcat gaaatacaag aaaattgtag atgaaataca caattctggt gcaaaggtat
    28861 cagcacaact attttgttca gattatgatg ttaatttaat taaagatact atgaatatgg
    28921 gaattacttc acatgatgag ataaaaaaaa taatgaatga cggagtaaaa gattacataa
    28981 caaatatgcc caaagaagaa attaaaaata ttataaattt atttaaagta acagcattga
    29041 atgcaaaaaa agcaggtttt gacatgattc aaattcatgg tgataggctt gtaggaagtt
    29101 tttcatcaag tatatttaat aatagaaatg atgaatatgg tagaacgtgt gataatagaa
    29161 gtagatttgc aagcgaaata attagtagta tccgagatga agttaaggac attccaatag
    29221 actataaatt tgcaataaga caagaaaatc ctcattatgg aaatgcagga gttttacttt
    29281 cggaagttga gtattttgtt aaaaaatttg aatccctagg tgtaaacagt tttcatgtaa
    29341 cacttgcaaa tcattcaaaa ttagaagata ctataccaac caataatcat ccttacttta
    29401 aagaagaagg ctgtttttta tatttagctg atgaagtaaa gaaacacaca aatcttccag
    29461 tatgtggggt tggaaaattg tctagcccag attttataga aagtattatt tcaaataata
    29521 gagtagatat ggtttctatg tcaagacaat tactagcaga tagtaattgg ttacagaaag
    29581 taaaagatgg aagagtagat gagattaaaa agtgctgtta ttgtaataag aagtgtgcag
    29641 atgctttaca aacacgctct cagtttggat gtatactaga ttagaatatc cttataaaaa
    29701 taaataattt gttaaggtta atatattttt ggtgatttag ataaatattt agataaagag
    29761 gaggagacat catgaaaagt ttagttttat attcaagttt aactggaaat actaaaaaga
    29821 ttgcttatac tatatatgat gaaattcaag aagaaaaaga cattaaagat gtaaatgaat
    29881 tagttgatta tggtattgac tatgaaaatt atgatatagt attcttaggc tattgggtgg
    29941 acaagggaat ttgtgataaa aattcaaaac aagtgcttga aaatattcac aataaaaaga
    30001 tagcactatt tggaacaatg ggagcaagta aaaaaggaag ttatggagct agtataatag
    30061 aaaagataga atcaattatc ccaaaagata atgaaatact aggttcattc atatgtcaag
    30121 gtaagatagc agaaggattg aaagcaaaat ataaagagat gttaaaactt tctcctgaca
    30181 acgaacatat tcgccaacaa ttaaataacc atgaggaatc tcaaagtcat ccagatgaac
    30241 aagaaatata tgaagccagt atgtttgcaa aaaatatgat gattaaagct agtattgtgt
    30301 agtagttaaa caataagttc atataagata tagaataaat aatttagtaa aaaagtatag
    30361 caaataattt gctatgcttt ttttatgaaa tcaaaaaaat aataaaaata cttgactgta
    30421 aaccttgttt atacattatt ttatagaaaa taagatagtt ttaaatataa aaaaagatat
    30481 attattgaaa ggagatatta ttgtatgaaa acttataaaa gataattagt ttgattttaa
    30541 gatatactaa atatacaatt ttatagagtg aaaatattta agactatatt atagttataa
    30601 attaatagaa tagagaggta gtgtttaaat tgcaataaca gtatttcaaa agttgccacc
    30661 tcaaattcct atccaatgga ataatggtgt agctaattat gtagataaaa aatttattta
    30721 tgcctaccct gtcatttgtg ttgtattcag aatactttta cgtccattta tatggagatg
    30781 gttacaaata catgcttttt atagtgatac tattgcagat tatttaacga attttatgtg
    30841 ttttgtagcg ttgtctatag aaatattctc tatatttttt atttacaata ttgtcagaca
    30901 tgttacaata attattttta tagatatact tgtatttatt gctttactga taataggtgt
    30961 gtataaatta tttaaaaaat acaattaatt tttaaaaata agtaataagt gatagtgtaa
    31021 aaagtagcca ctgcaaatta tggattgtag tggctatttt attatttgta tatgaaatta
    31081 ttttgttttt ctaataagtt acgatatatt atggtttatt tcactgataa aaggtttagg
    31141 tattttaaag taaaaagttg tatattctaa taaaatttaa acattttgat tctttaaaat
    31201 tagagaaaat acattgcttt tattaaaaaa ttaaatatta agaatttaat ttctgcatct
    31261 tatttagaaa agataagaaa tcaactttat atattttttt tggccttcct ctttgattat
    31321 cgagttttgt atttacaata gttgcaattc ctgctttata taagatactc aatattctat
    31381 tagcacttct aagagttatg ttcatatagt ctgctaatat ttctgctgac acattatttg
    31441 aatttctatc attaatcata cacatgattt tagatacatt tgtattagat agaggtataa
    31501 aagaagcaac tttattggct attgagctat cttcaatatt attagaattt ttatttgaat
    31561 ataaagggcc tattgtatca ttagtatcat ttactataaa agtacagttt ccattcaaag
    31621 aagcagattt accattagct tgacgagcat tttgctctgc atgaatattt gtatttccaa
    31681 tgccccaacc tatatttaag ctatatttaa tttcttttaa atcttctgaa ataaaaaaat
    31741 ctgtatagtt attggtcata ttgtttaaca tttctttagt agtgtgtatc tctattttca
    31801 tatcattttt tttgacctga actccataga atccatgtct tgatagagaa tttaatatag
    31861 tgttatatat ttgattttgt atctcatcat ttttaaatat caaatcttca tttatgtact
    31921 ctgaactatt tactgtaact atacaagttg cagatttatt tttgtctaag ttttgtaatg
    31981 ttatttcatt caccagagat ttaaatgtat tcaggattga ttctgtagat ggaaccatgt
    32041 aaatagaatc atatccaagt ttattaagtt cacaactaat gatgtaattt ctagtaaaag
    32101 aaaggttaat cttattatct cgcaataagt ctaaatgtat ttccaataat ttatcattta
    32161 attttttaaa gtcatataca ggttgaggga tattaaaatc tttaattgta tatggacatt
    32221 tattagagtc tattaatgaa tatatatcat aataattgtt gtcctctctt aaaaaatcca
    32281 taaatgattt tgtaaagtca atatcttttt ggctatttaa taatttgaat aagtatttat
    32341 aaaaatcttt ttcatcaagc tttaaaaaat ttaatggaac ttttatgtct tttatattta
    32401 ttataagttc actatatgga actataccac tgcatacaaa tccatcaaaa ttatctactt
    32461 gctcatagta tatattaggt aaattattaa aaggattctc ccctttaagc tcaataaatg
    32521 taatttcaca agtatcattt aattctttaa gagcttgttt aaacttatct gacataaaat
    32581 aagatgttgt caaaaaacca attttatatt tcataaaacc tcctttaaaa tttcgagagt
    32641 attgtaacta atcaatcaat ttataacctc attttataat agtagataaa acgcgtcaat
    32701 ttattttaca aaaggaaaat tgaaagaaaa atcagaaaat ataaaaaaga ctgaaaaata
    32761 tgttgactgt caagaataat tgtgctattt tgtaattaag gactagtctt ttaagatttc
    32821 ctaaaataaa cttagatttt aggaaagaaa tacattttat ttgaaaataa aggagaagat
    32881 tatgaataca tatttaaatg aaatttctaa gtttgttgat gagaatagag aagaaatagt
    32941 ttcattatgg aaagagattg ttaatatgga aagctataca cattgtaaag aaagcgtaaa
    33001 taaattggct aagagattaa agtttgagtt tgaaaaagaa ggtttagatt gcgagttagt
    33061 agatgttgga gataatggta gtacattgat aggtacactt ggttccaata tagataaaaa
    33121 gccaataatt ttttcaggtc acatggatac tgtctttgaa acaggtacat ttggagagaa
    33181 tccatttaaa ataatagaag gaaaagcata tggcccaggt gttttagata tgaagggtgg
    33241 tataataatt tccttatatg ctattaaagc attaaataaa ataggataca aagaaagacc
    33301 aataaaaata gtattttctg gagatgaaga gataggacat aaggattcaa caggtgcaga
    33361 tgttatattg agggaagcaa aaggtggtct ttgtgctttt aatatggaaa ctggattagt
    33421 agataatagt ttgtgtgtag gtagaaaagg aagaatagga tgtaatatac atgtaaaagg
    33481 tgtagaaaca cacgcaggta atgattttga aggtggaaga aatgctatag aagaaatggc
    33541 taataagata ctacgcatac aaaaattgac taatttagat gttggaacta cagtaagtgt
    33601 aagtgtgatt aagggtggaa gagtggaaaa ttctattcca gaagattgta gtataaaagt
    33661 agaccttaga tttgaaaaag tagaagaaat ggagaatgtt aaagaacaag ttagagagat
    33721 atgtaaagaa acttacatag aaggaacttc tacagaagtt aattttataa gtgaaatgat
    33781 gccatttgaa actacagaag atgttatgag atttcataca tttgtaaatg aagtgtcaaa
    33841 agaaaatgga tttggagaat taaatgctaa gagacttgga ggtagttcag atgcaagtta
    33901 tttaactatt gcaaacgttc ctacaatctg ttcatttggt gtaagaggag aatggaacca
    33961 cacatcaaga gaatatgcag tagtagattc tatgtttgag agggtgaaat taatttctac
    34021 agttatttta aacttagata aatttgaggt ataaaggggg attttatatg gatgtaacag
    34081 ctggagataa taaggtaaca tggaaagggt atttatcttt atttgtattg atagtattat
    34141 tttcaggagt gtttaaagat agtcaaggct tccttaaagc attagatttt gctaatctga
    34201 caggttcatt tggtactatt gcagatggtg tagactttat gggtaaagga ggaacgggag
    34261 caaaagatgg tttcttattt gctctgactt tgattccaac tgtctgtttt gctgtaggtc
    34321 ttatagatgt agttgaatct atgggaggaa tgaaagcggc atcaaagata tttaatccat
    34381 tgcttagacc tctgcttggt atacctggaa tagcaggaat agcatttgta tcttcattta
    34441 ctagttcaga tgtagcctca ataatgacga aagaattatt tgaaagtggg gaaataacag
    34501 atgatgaaag aactatattt gtagcatatc aatatgctgg ttcagctgtt atactgaaca
    34561 caataaatac tcaagctcca cttttaccaa tagcattatt ggcattaggt ccaataatac
    34621 ttatagagat attctgtaaa atacttggtg ctaatctagt tagattaatc ataggtgtaa
    34681 gaaataaaaa gaataaggct aaggaggctg tgtagtatga gtcaacaaaa tactggaaat
    34741 gtaattgtaa atagtaaacc taagaaaact gctgttgaga tatttatggg gggagcaaaa
    34801 aaaggttttt acataggtgt tgaacagata ttaccagcca tgataatggg ttatgtaata
    34861 gtgcagtttt tacaattaac tggtttagtt gatattttag gaaatatttt tggaccagta
    34921 atgggtattt ttggactacc tggggaatct gttgtagttt tgatagcagc attctttgct
    34981 aaggcagcag gagcagctac agctgcaaac ttatttgcac aaggtctaat cactgcacca
    35041 caagcaacca tattaattat gccatgtatg ttaatgggta ctctagttgg tcattatgcc
    35101 agaatagtgc ttgtagcaaa tgccagtact aagtatagaa tgttactgtt ggcagttcct
    35161 atatttgatg caatagtggg gatgttgata gtaagagttt tactcactgt tatgggatta
    35221 atgtaaataa cataaaatta taacctaact ataaatgata tataagaatt aatatataca
    35281 aggattaatg agtagtaatt gatatatagt aataaactaa gatagtaatt aatgtgtata
    35341 ttaattaaaa aaagagagta tctcaaagtg aactttttag ttcatgagat actctttttg
    35401 tatgaaatca agtatatttt cataatttca acaatgaaag agaggcttat ctctattttg
    35461 agacagcctc ttcttttaaa tttatatttc tagaatttat gttttttatt tatccaacat
    35521 taacattagt tattagcaat aattttaaga aaaatatact ttcatgttaa tatcagaata
    35581 aatgtgtttt taaaggatga tttgttttga attttcacga atatctactt ctatgacttt
    35641 ttctattgta tctcctctaa aacctaataa attacttgtc aagtttgcag tggaacaaga
    35701 atgattaggt ataattctta ttctatcacc aatttttata tcagtttcac catttacttt
    35761 aatttttcca acttcttctg aaagtgaatc aatagtaagt tctggatgtc cacataccct
    35821 accataacca acaatactac tatttccatg tgcaccttta tcaagtccaa ggcacttact
    35881 tccacaatca attaaatagt atccactgct attttttgag attacagtgc acacaacagt
    35941 aagagcacac atatcttcag tagcacaacc taaacctatc tgtatagcat catagtatac
    36001 atagtttcca ggtcttacag cagttatagt tttagaagca gcttcagatt caactgttgg
    36061 agtactacca gaagcgacaa tttctatatt aaatccatta tcagttagag ctttgtatgc
    36121 tttctccata gaagaatctt cttgaacaca aacatctgga acaccttctg gagaactaca
    36181 accatacact tgacctggat gcgaacttat accaacaatc ttgatgtttt ctagcttaga
    36241 aatttcagta gcaagttcaa ccactttttc tggttcaacc ccaaaacggt gtaagccaca
    36301 atctacaata ataagtagct tgcactctat ttttgattta gaaaaagctt cactataagc
    36361 cttagcacat tctatattat ctgtagcaca gattaaattt atttttgatg ccatagtcac
    36421 aattctattt atatttactt ctcccatgta aggataagcc aacataatat cttcaaaacc
    36481 tgcttttatc agagcttcac cttcatcaag tgttccaact agaaaaccac tagcacctgc
    36541 atttttttga agtctcgcta tgtaagtact tttatgtgtc ttaagcatag gccaaagttg
    36601 tttattatta tttgtacaaa tttgttgaat tttatctata ttcttttcta actggtctaa
    36661 atctagcaaa aaatttggag tagcgacttc tgaaattttc atgttattta ccacctttca
    36721 acaaaagtaa attaactata agtattataa ttattatatt agtaatatcg gctttataat
    36781 attaatagct tataattata ttatagaact agcgttaaca gagagcaata tttatttgta
    36841 ataattagaa ttttcaataa gttagtgtag ttttaaatta tttatataat atatttttaa
    36901 ttttatacaa agtttattta aattagtttg aggatttatt aatagggtat tattgaatga
    36961 gtaaaaaagt gatgtttaca tagaataatc acactataaa ttaatttaga acctaaaaaa
    37021 ttaattgagc aaattggaaa agagaaggat aaaaaagata tttggatagt tggtggaggc
    37081 gatatagtaa aattatttat gaaagataac ttaattgatg attattatat atatatattg
    37141 acaataatat tggggagagg gatttcacta tttaagtctg gtatagataa gactaatttg
    37201 aattttaaga aagctagtaa tattggagaa cttgtaaaat tggaatacag taaaaaacaa
    37261 aaataaatta catgccaatt tgttacaatg ttatgaaacg aagcatttaa aagacttttg
    37321 gctatatgaa ttgacattac ttgtcaaata tgttaacata taagcgactt gtcggagggt
    37381 gtattaaaaa gaatatgctg gagaagagag tgcgttaact cttttctcct ttttttataa
    37441 aattaagcat ttataaattt agtattatta catgattaca ctatctcaaa aattaagaaa
    37501 ggagaaaaat atgaaattaa ttttaagtta tttaaagaat tataagttat taatagtatt
    37561 aaacatactg gctatattta gttttgcatt agtcgagttg gggattccaa ctataatagc
    37621 taaaataatt gacaatggta ttgcaaatca gaatatagct tacataaaac aaatgggaat
    37681 agtgattgtt attatttcta ttataggggt tgtaggtagt atattgttgg gttattgttc
    37741 tgctaaggta tcaacaagtg taaccagaga tataagaaat gacatatttg agaaatcaca
    37801 agaattttca catactgaat acaataaatt tggaatttct tcaatgatta caagaacaac
    37861 gaatgatgca tttcaaattc aacaatttgt taatatacta ctaaggactg ccttattaac
    37921 tccagttatg ttcattataa gtataataat gacaattaga acaagtgtgg aactttctat
    37981 agtattggct atatcagtac cttttataat tattggagta gcaataatag caaaagtatc
    38041 tcaggcaata tcttcaaaac aacaaaaagg actagataaa ttaaacctta tatcgagaga
    38101 aaatttaact ggaataagag taattagagc ttttggaaat gatgattatg aaacagagcg
    38161 atttgaaaaa acaaatacat attatgctaa tgtttctaag aaactattta agcttatgtc
    38221 aattactcaa ccagcattct ttttactatt aaatatagct gttttggctg tattttggat
    38281 ttcaagtgag aagataaata ttggagagct tcaagttgga cagttggttg catttttgga
    38341 atatcttttc catgccatgt tttcaattat gcttttttca atggtattta ttatgtatcc
    38401 aagagcagag gtatctgcaa atagaataaa agaactatta aatgaagaac cattgataaa
    38461 aaatcctgaa aatggaatta aggatactga aaataagggt atcatagaat ttgataatgt
    38521 aacttttacc tatccagatg gagaagcttc tgtacttaag gatatttcat ttactgcaaa
    38581 aacaggtgaa acagtcgctt ttataggaag tactggtagt gggaaaagta ctctaattaa
    38641 cttgatacct agattttatg atgtaacaga aggtagcatt aagataaatg gagtagatat
    38701 aagagaatat gatttaaaag ctttaagaaa aaagatagga ttcatacctc aaaaatcact
    38761 gctttttact ggtagcatag caaataatat tagatttggg aaacataagg caggagagtc
    38821 agaattagaa tattccgcaa aagttgcaca agcatatgag tttatatcaa aaaaacctag
    38881 aaagtttgat gaattgatta gtgaaggtgg agcaaatgta tcaggaggtc aaaaacaaag
    38941 actttctatt gcaagggcta ttataagaag acctgaaata tacatttttg atgatagttt
    39001 ttctgcactt gactttaaaa ctgatgcaat acttcgtgct aaattgaaga aggaaacaaa
    39061 agatgcaatt gtattgattg ttgcccagag aattagttct attattgatg ctgataagat
    39121 tatagtactc aatgaaggac aagttgtagg aatgggaact cataaagaat tattaaaaaa
    39181 ctgtgaaata tactatgaaa ttgcaacatc tcagttaaaa aaggaggaat tagaataatg
    39241 aaaaagtcta aaggttttaa gaaaacaatt ggtagacttc ttccatttgt aaagaaatat
    39301 aaattttcct ttattatagc tattatatgt ataatttcag cagctactat gaatgcactt
    39361 gcacctaaaa ctgaaggatt gataataaca caattgacta aagatgtaat tagtatcgca
    39421 aaaggagtac caggggcttc cgtaaatttt gattatgtaa caaaaatatt ggtgatttta
    39481 gcatgtatat attttgccaa tgcaattttt acgtatactt caagttttct acttacgaat
    39541 gctattcaaa acacaatgag agatttaaga aatgaagtcg aaaataaaat aagaagattg
    39601 cctattagtt attttgatag taatagtttt ggagatgtat taagtcgtat atcaaatgat
    39661 gtagatacaa tatcaaatgc attgcagcag agttttatgc aaattgtaaa ctcaatctta
    39721 gtcataattt tggcactttc aatgatgttt acaattaata tatatatggc tcttatagct
    39781 ctttttataa ttccaattag ttattttgta tctaaatttg tagtaaaaaa atctcaaagt
    39841 agattttcat tgcaacaaaa tgctcttgga aaattaaatg gaaaagtaca agaaatgtat
    39901 actggattta atgaaataaa actatatggt aaagaagaag attctataaa agaatttaaa
    39961 aaagtaaatc aagaactttg tgaaaatgga tttaaggcac aatttatatc aagtatgatg
    40021 aatcctatgg tttcattagt aacttacttt ggaattgcag ctgtggcagt tgtcggttct
    40081 atatatgcag taagtggagg aataacagta ggaaatttac aagcatttgt gcgttatata
    40141 tggcagataa atcagccact ttcacaaatg actcagttat ctacagtaat acaatcttct
    40201 tttgcagcta tagaacgtgt atttgaaatt ttagacgaag aagaggaaat acctgatgtt
    40261 gaaaatccag ttaagataga aaatgtaaaa ggaaatgtta catttgagca tgttaatttt
    40321 ggatatggag aaaattcaac tttaatagaa gatttaaatg cagaagtaaa aagtggtcag
    40381 atggtagcta ttgttggacc tactggagca ggtaaaacaa cattaataaa cttattgatg
    40441 aggttttatg atgtaaagaa aggtgctatt aaaattgatg gagtagatat aagagatatg
    40501 aaacgtaaag atttgcgttc aatgtttggt atggtgcttc aagatacatg gttatttaat
    40561 ggaaccattt ttgaaaatat agaatatggt agatttgggg ctactaaaga agaaattata
    40621 caagcagcaa aagtagcaaa tgttcatcac tttataacca ctcttccaga tggatacaat
    40681 atgtttttaa atgaagaagc atctaatata tctctagggg aaaaacagct tttaaccata
    40741 gctagagctt ttatatcaga cccttcaata ttgatacttg atgaagctac gagttctgtt
    40801 gatactaggc tggaacttat gcttcaaaaa gcaatgagaa atcttatgaa tggtagaact
    40861 agttttgtta tagcacatag actttctaca attcgcaatg ctgacttgat tttagttatg
    40921 aataatggaa gtattataga gcaggggaat catgatgaat taatggaaaa gggtggattt
    40981 tatgagaagc tttataatag ccaatttgca gacaaagaat cagaatagat aacataaact
    41041 tttgtataaa attttgtatc aaattcaaat attaatcata taattaaaaa gagtatcagt
    41101 aagttgtttt tttatagatt tactgatact ctttgatttt aagactaaag gtacttatga
    41161 ttggtactta taattcacaa ctagtcttgt tacatctgat aaccagaatt acagtacttt
    41221 tcttttttac ctttttgttc tctaacatat aacaattcgc ttaacttatc aatgtaataa
    41281 ccatcatcac ttatgcgaat taaactagtc agataatatc catctttgct tctaggaatc
    41341 tttttattta ttgctaaatc aatagctgtc tttgctgctt caaaatgctt taaatgtgta
    41401 tgaccttctt caaaactctt tctagtatta taaactacat aacctttttt aacttgaaaa
    41461 actataaatt ctttcttttc atatatttta ttaaacattc aatcagccct tctcaagata
    41521 gttttatagc ataacattag aagcttctaa aaaattttac aaagaacata aatattttat
    41581 aaattataaa tctaaaacta taatttataa agataacttt ctgattattt atatgataat
    41641 tcatatagat taaaagtaaa ttatctttag gttaaacaaa agtaaaataa aagactagtt
    41701 ataatattta tatgaaaaag tacaaaatat agtatatgaa tatagaaaat ttaaatcatt
    41761 tatttacagt ttttatttcc ataagtatat ttaccttcag ataccttgtc atcatggaaa
    41821 tatattcttt cacaactttt atctccccat agaatgtttt ttgttatttt atgggacgta
    41881 tctcctgtaa atacttcagc tacagtagta tctgtaacat cacagtaaag agaagcaaat
    41941 tttttaaacc aaggattttc ctcaaatctt aaaagccaag aagctccata ggggcaatgt
    42001 aactcttcaa attcaggaac ccatcctaga aatggaacat cagttgtgct aataatattg
    42061 tctgcgatta attcatctcc attttcatga gctctctctc tcatagcaat agctctttct
    42121 tcagaccttt caaataaaac ttttcttaat atttcgctag ttttatcttc accaaactct
    42181 tcaaataaca ctttggaaaa ataaaaatat aaatcaccaa aatgtttgca tgccatacga
    42241 acttcttcaa tagcataatc tttgtcaata gtttcattag ttacaacatc ttcgttcaaa
    42301 aaaatcactc cttagaataa gtattagtta caatataatt atagaatatt ttttataaat
    42361 taggaaatta atttgagata gatatatttt taataaatga aagtataata ctaaaataac
    42421 ttattgttac aaaaatcttc taaattaatg tatttaggag tttccatatg aatgagagta
    42481 gttctgtaaa tatcttcaat acatccattt gcaatattat taaaaatatc tgtgtgctct
    42541 tttaatgttg tttcaagcct tccttcatgt gacaatgaat cgagagctaa tttttttatt
    42601 ctgtacatat aattgttaaa cattttgtca aattcagtat tttgagcata tgaaactata
    42661 gttgtgtgaa ataatgtatc gtattctgca aatgagttta aatttttatc acctaataaa
    42721 atatcttttt gtttatctaa aagatgtttt aatttactta tagtttctac tgctctagct
    42781 tctttgtatt gacttgtaat taaaaaagta caaaatcctt ctattgcaga gcgtatttgg
    42841 aatatctcta caatttcatt tgctgtaatt tgatggattc taaatccttt gcttgggatt
    42901 atatctataa atccatcttg actaagtctt tgaagagcat ctcttatagg tgttctagag
    42961 atacctattt cactagcaag ttttgtttca gaatatattt cattttctat catttctcca
    43021 gatagtatca attcttttaa gtagtcatat gcttgttctt gtaatctttt aaatgtagcc
    43081 atacttaata atacccccct aaacaatata aaaatacaaa aacttatata attttaagca
    43141 tacaacatag tgaaaataag gtcaatcttt tgcaatttaa attgcagata agattaaaaa
    43201 atataaaaaa ttattgaagt gtgaagcatg attaacatta aaggcagatt aattaaaact
    43261 aattgaaatt agttaaaata caaaactgta aaagtagtat attatatttg aaaacaatag
    43321 tatgtattaa aacttatata ggatgactaa atataataaa tgactttaaa aattactatt
    43381 tattgttaaa ataaatactt ttatatttta tattgaccgg tatactggta tgtagtatac
    43441 tctaaaacat aaaaaacgtt ttcaaaaatg tgaagatatg gagggttata aaatgaaatt
    43501 gggatttatt ggattaggga taatgggaaa gccaatggca aaaaatttat taaaagatgg
    43561 atgtaatctt ttggtgtatg acattaataa atctgctgtg gatgaactta tatcatgtgg
    43621 agcaaaatac gcaagtgttt tagaaatggg tcaagaatgt gatattgtat ttacaatcct
    43681 tccaaatgga actattgtgc aggatatatt gtttgggatg gatggattgg caaaaacttt
    43741 aaaagaagga agtatagtag tcgatatgag ttcagttact cctacagaat caatattgtg
    43801 tgcaaataaa ttaaaagata tgggcttaga atttatagac tcaccagtaa gtggagggga
    43861 gccaaaagcg attgatggta cacttgcttt tatggctggt ggtaaggaag aaatttataa
    43921 gaaagtagag ccatttttta atataatggg aagctcatct attttaattg gagataatgg
    43981 tagtggaagt gttacaaaac ttacaaacca agtaatagtt aatttgacga tagcagcagt
    44041 ttctgaggca tttgtacttg cagcaaaagc aggtgcagac ccagaaaaag tatataaggc
    44101 aataagagga ggcctagctg gtagtacaat attggatgtg aagataccaa tgattatgaa
    44161 tcgtgatttt aaaccaggtg gaaaaatatc tattaatttg aaagatatta agaatgtaat
    44221 gcaaacagca cacaatttag atgtaccact acctatgaca agtcaattat tagaaattat
    44281 gcagacatta aaagtacatg gacatttgga agatgaccat agtggaatag cacagtattt
    44341 tgaaaagttg gcaggtgttg aaataaaaaa acacgataat taatatttaa atatatcaat
    44401 ataattaaat acatattatt aggattagat tatataaata cagcgaggtt aagttatcat
    44461 agtaaaagaa aaataaaatt gataaataat aaagtagaat gataaagggg taaagattat
    44521 gattacagga tatggacttt tgatagcatt tgttatatct ataggaattt tacttgtatc
    44581 gattattaaa tttaaagtaa atccgttttt ggcattactg ataacatcta taattacagg
    44641 ctttatggtt agaatgccta taaatgaaat atcaaccaca atatcgactg gatttggaaa
    44701 tacattaggt agtataggta ttgtaattgg acttggaata atatttggaa atattctttc
    44761 agaatcaaga gcaacagaat ctattgcaaa ggggttgtta gctaagaccg gagaaaaaaa
    44821 cagtgcttta gcagtaacta cagcaggttt tttaatttca attccagttt ttatggatgc
    44881 agcttttgtt ataatgatgc ctataattaa gtatgtttcg agagtaacta agaaatctct
    44941 aatggttttt gtatgtgcct taggagttgg gactatagta ggtcatgcac ttgtaatacc
    45001 tacaccagga cctttggcag ttgcagcaaa tgtaaatgca aatgtaggta gttttatact
    45061 ttattctata attgttgctt ttccagcagc tcttataggt ggatggattt atggaaaacg
    45121 ttttgaaaaa tatccagctt atgctattga tgagaatgat agagaaaaaa atttagagca
    45181 gggaaaagat agcataaaaa ttgaagatga tgattcttct aaagtaccag gttttggaat
    45241 ttctatgttt tctttattgt tcccaatact tcttatactt atatcaaatg tatttagtat
    45301 gttcttagaa aaaggttcta caatgagtgg agtacttgca tttataggag ataaaaacat
    45361 agcaatactt cttggaatat tggtggcaat aggattttta aagaaataca taaataaacc
    45421 tatgggagat gtagttattg aagctgctga ttcagcaggg ctaatattat tgataacagg
    45481 gtcaggtggt gcgtttggca gtgttataaa tgcaagtggt ataggtaact tcttagttga
    45541 tactatgtct ggtcttagta tatcagttgt agtacttgga ttcttattaa gtgccttgct
    45601 tagaatttct caaggttctg ctactgtagc cttagtaaca acatcatcaa ttttaggacc
    45661 tacaattttg gcaactggaa tgtcaccagt tttagtaggg cttgctatat gtgctggagg
    45721 agttggtttc tcccttccaa atgattctgg attctgggta ctttcaagat ttagtggatt
    45781 atcagttaaa gatactttaa actcttggac aattggagga accattgctg gagttgtagc
    45841 atttataatg gttttattgc ttagtgttat aaatggaatt ataccacttc caggtctata
    45901 aataacaaac tattgtttat atcatataaa ttatatttag actatacaaa ttacataaag
    45961 gggcgtttta aatgagagaa gtaaaaccaa ttagcataga tatacttaat acttttaaac
    46021 aagtagatga ggatagatta aataaacttc ttgcagatga gcttaagcat ttagatagaa
    46081 aaattgttgt attagatgat gacccaacag gtgtacaaac agttcatgat atttctgttt
    46141 atactgattg ggataaggat agtatggaac aaggctttaa tgagaaaaat agtatgtttt
    46201 ttatacttac caattcaagg ggatttactg ttgctcaaac tacaaaagca cataaagaaa
    46261 tttcaaagaa tattgtggat gtatcaaaga aagttaataa ggattttata atcataagtc
    46321 gtagtgattc tactatgaga ggacattatc ctcttgaaac taatttatta aaaagcgaag
    46381 tagagagatt atcggggaag ttatttcagg gtgaaataat aatgccattt tttaaagaag
    46441 gtggtaggtt tactatagat aatgtacatt atgttaaaga aggagaaata cttgtaccag
    46501 caggaatgac tgaatttgca aaagataaat cttttggata taaatcatct gatataggtg
    46561 agtggtgtga agaaaagaca aatggaaagt acaaatctag tgatatgata tatatttcgt
    46621 caaaagaact tagagagcta aatattgaag ctataacaga aaaacttaaa aaagctgaag
    46681 gattcaataa aattattgta aatgcaaccg attatgtaga tgtaaaggta tttacaattg
    46741 cgtttatacg agcagtaaat ggtggtaagg aatttatgtt tagaagcgct gctgccataa
    46801 caaaagtact tggcggagtg agtgacaagg aactacttac taaggatgaa ttagtatcaa
    46861 aaggtaatac caatggagga attatacttg ttggttcaca tgtgaataag actacccaac
    46921 agttagaaga acttaaaaat tgtaaatatc cgatagaatt tatagaattt aatcaacatt
    46981 tagttcttca agaaaatggt ctaaaaaatg aggtaaaaag agttataaaa gttgtagagg
    47041 aaaaaataag cagtggtaaa actgttgctg tttatactag acgagagcgt tttgacttgg
    47101 atacgaatga taaagataaa cagcttatga tttctgtaga aatatcagat gcagttacca
    47161 gtataattgg tatgcttaat gtaagaccaa attttattat agctaagggt ggaattactt
    47221 ctagtgatgt tggtactaaa gcactaagag taaaaaaagc tacagtaatg ggacagataa
    47281 aacctggtat accagtatgg atgacaggca aagaaagcaa atttcctaat atgccatata
    47341 taattttccc tggaaatgtg ggagagatta gcacacttag agaatcagtt gagatattga
    47401 tggggtagta tattagtgta ttgaagttta aacgcttaaa tttactgagt taaaattaaa
    47461 ataaactaaa attataaatt aagattaaaa ataatagtat attaattagg gtttagagta
    47521 ttttacaaaa aatattctaa accttaatct tatgtattag tatttttatt atttaactta
    47581 tgtgtttatt ttattattta tcttttttaa ttgatttaat attttctttg attttattta
    47641 aaatatctgt atgcttatta gagcttatgt tggggaatgc tttgattata cgtctatgaa
    47701 gtaatttgtg gttagacagc aaagtattaa gtttattttt tagctcatca atacgatttt
    47761 tagcatagcg ataattttct ttttctttaa gtatttcaaa cctatcttcc aaagtatcca
    47821 gtctattttc aactaaagat tcaagtttgt tttctatagt ttcttgtgta ataagtttgt
    47881 agtattcttt cttatctttt aattccttaa ttataagatt gatttgtttt aacttaccat
    47941 ttaattgtaa aattgtatgg actgtgataa ctaaatctaa aacaaaataa atttctatag
    48001 atatagcaaa tataaatagc acatttttag agatagagtt aataaagtca accacaatag
    48061 gatgtactat aagcattaca atcaatgata atacaccaaa cataagtgag ttttccagac
    48121 aaactcttcc atgaatatta aatttatgtt tagaataatc ccaccaagtc atattaaata
    48181 ttttttctaa aataaagctc gtacagtact ccattatgct agttataatt atactaaaca
    48241 aaaataacaa aggaatattg tgtacaaaag gagtcaaggt agcaactatt gctaatgctc
    48301 caaatccata tatagggcaa aatggaccat ttaaaaaacc tctatttaca aattgttttt
    48361 gtaaaactga acaatatgta gtttcacaac accatcctat aaagctataa attacaaaat
    48421 aaagaaattg aatataaaat gtactcataa gcacctcatt tctagttagt ataacactat
    48481 atactcgata ttttattttt atgattaatt tactaaattc aatttacata ttgattatac
    48541 caatttatag aaatttatca aatttaatta cagttagaac attataaaca tggttataat
    48601 aatgaaattt tatttaaaat aaataagggt gtcaagtata atcaaactaa tagttgtaga
    48661 tactctacac tatgttagtt taattacatt tgacaccctt atatttatac tatgactatt
    48721 tacattcgaa actagagcaa catgtttcaa tataaaggtt tactctatca gtttcaggag
    48781 caaccaatat attatcaagt gtacataagc taccatcttt gttgtattta caatttttta
    48841 cagtacaaac taattcctca caatttttat tattaacgtt gctagataaa ttactataaa
    48901 tagattcatc taaaaatgaa ctacaacaag tatgtctgtc attgtgagct ttttcaccat
    48961 ttataaaaat tttatctgca taacatatat ggctgttgtt atgtgaacag ttaattacat
    49021 tacagtttat tctttccaaa gttattacct cctaaacgat tatttattat aaattatgtc
    49081 catataatta caagaatata accattaaga gaaaactacc ttttagaaaa tatctattct
    49141 tagagtaatt tgaaatataa atatattttc ttctaaaatt tacctaaatt gtataaaaac
    49201 ttacagcttg gagaaaataa tagaaaaagg aggcgtaatc aatgtttgaa aagaagaaaa
    49261 aagaattatt tccttggaaa atatctgcct taatactggt tggagtattt gtattaagta
    49321 gcggagttta tatagggaca agattaaaac acaatggagt tcaaactggt gaagttgtaa
    49381 gtactagtgc gaatatgaat gaaaagtcaa aagaagcttt tggattaaat aaaaattgtg
    49441 aagtttggct tcaaagtgaa ggcgaaaatg aaactaacta taagagaaca cttacaatgg
    49501 caggaatagt tccagagtca ttattagata agacgaagtc agaaatagta tcatatttta
    49561 aaaaagaata tccaactaaa aaaataaaga gtatggataa aaatgaaatc atattggtag
    49621 aatctaaata tagtgataat aaagatgtac aagcaatgga tgttactata aaaggtaaat
    49681 atactattga aaatgataat ggaaatatag cactatataa atatgatgat agcggaagta
    49741 aaacattagt agaaaaaaca aaaataagag tagattcact tcctaaaaca gttcaagatg
    49801 aaatcaaaaa aggtgtagtt atggatactg aagaagaggc ctattcaaga ttagaagact
    49861 ttgcaagtta atagtaaatt aatattattt taagttaaat actaagtaaa ttaataataa
    49921 ataatttaat attaaataga ttagtattaa aattgtagtc acatttaatt cctataaaaa
    49981 tacaataatt tatttgtaat aaatataaaa gttatattga ggtaaaatct tgctttgata
    50041 taactttttt atttgatttt atattttaca tagagcattt tatgatttgt taatattatt
    50101 tatgatataa tgatttagaa cataagtttt tatgagaaat acattttggt atttctttta
    50161 tttttagggg gaattttaaa aaatgataat attggggatt gacccaggta tagccatagt
    50221 tggatatggt ataattgaat acaaaaatag caagtttaaa gcaatcgatt atggagcagt
    50281 tacaacacct gcccatatga atatatcgag aagattggaa cttgtgtata aaggaattga
    50341 tacaatagta aagaattaca atatagatga agttggaatg gaagaattat tctttaacaa
    50401 gaatgtaaaa acagctataa cagttgcaca agctagaggt gttactatgc ttgcatgtgc
    50461 tcataatggg aagcctgtat atgaatacac tccacttcaa gtaaaacaag gtgtagttgg
    50521 atatgggaga gcagataagg cacaagttca acagatggta acttcatttt taagtctaaa
    50581 aaaagttcca aaaccagatg atgttgcaga tgctttagct gtggctattt gccatgctca
    50641 ttcaaacaaa cttgaaaaaa ctctaaagaa tataggtggt aagtatgtat agttatataa
    50701 aaggtacagt agaagaaatt tatatagaca gtatagttgt tgaaaataat gggataggat
    50761 ataaaataaa tgtatcatcc aatacaataa tgaatttaca agtgggagaa gccacaaaaa
    50821 tatatactaa attaattgta agagaagatg atatgagtct ttgtggtttt gtaagtaggg
    50881 aagaacttaa gatgtttgaa ttactaacat ctgtatctaa aataggacct aaggtggcgc
    50941 tttcaatact atcatttgca tcaccagcac agttaggagc atatatttta agtgaagaca
    51001 ttggaaaatt atccaaagct cctggtgttg gtaaaaagac agcagaaaga atcgtcttag
    51061 agcttaagga taaggtagac aaaaataaca tagagtttga accaacgtta ttatcacaaa
    51121 aacctacctt gatatcacaa gatgagtctg tagatgcact tgtagcttta ggctatactt
    51181 tgtcggaatc aaaagaggca gttcaaaaat gtaaaaaaga tggtatgaat acagaagcta
    51241 ttataaagaa agcacttaca tatataatga gtaaatcctt gaaatagtat ttggatttta
    51301 taatatttgg attttaaaac aatatttaag gagtttatgt aaatttgaaa atatataaag
    51361 tagattttca aaagtacgag aggaggggta taaatgcaag gttttgaaga tgaaaatagg
    51421 ataataactt ctacaatgaa gatggaagat atagatatag aaaacagttt aagaccaaaa
    51481 actttagaag attatttggg tcaagaaaaa tccaaagaac aacttagtat atttatagaa
    51541 gcagctaaat cgagaaatga gcagttagac catgtgcttt tatatggacc accaggtctt
    51601 ggaaaaacta cactagcaag tataatagcc aatgagatgg gggtaaattt aagaattacg
    51661 tcaggacctg caatagaaag agctggagat ttggcagcca tacttacgaa tttaaatgaa
    51721 aatgatgttt tatttataga tgagattcat agaatcaata gaagtgttga agaagtttta
    51781 tatccagcaa tggaggattt ttgcctagat ataataatag ggaaagggcc atctgctaga
    51841 agcataagac ttgaccttcc taaatttaca cttattggag ctactacaag agctggtatg
    51901 cttacaaatc cacttagaga tagatttggt gttatttgta aattggacta ttatacagtt
    51961 gatgaacttt caaaaatagt acttaggtct tcaagcatct tagatgcaga gatacagtct
    52021 aatggagcat tagaacttgc aaaacgttca agagggactc caaggatagc aaatagatta
    52081 ctaaaaagag ttagagattt tgcacaagtc agagctgatg gaaaaataac tgataaagtg
    52141 gcaaaagatg ctctggaact tttaggagtc gatagtttgg gtctcgattt tgtagatgag
    52201 aagcttctta tgactataat agaaaaattt agaggaggac cagtgggttt agatacattg
    52261 gcagcttcta tcggagaaga tagaaataca atagaagatg tatatgagcc atatttgctt
    52321 caattaggat ttataaatag aggtcctaga ggaagagtag ctatgccatt agcatatgaa
    52381 cacttaaaaa ttccatatcc caatgaaaaa taaaaataga ttatacgagt atttataaaa
    52441 taaaagagtc attaaattaa aatatttcta aaatggctaa aaattcaaac atatccacaa
    52501 aatggtaatt atatctgtag atactgtgga taaacacgat aaaaattgtg tgtattgtat
    52561 ctatatattg tggataaggc atgtatatcg tggaaaaata tctatatatt gtggatatgg
    52621 tgtctgttaa aaatagcaat ttcttgatag attatggtaa tattgtggaa aataagttgt
    52681 ttttttgata ttattgtagc tggagaaatt ttaagagagg aagtttaaca ttgaaaacaa
    52741 gtgattttaa atttgactta ccacaggaac ttatagctca agttcctata gaagatagag
    52801 ctagctcaag attgatggta ttagataaag agacaggtaa tattgaacat aaagtattta
    52861 gagatataat agaatattta aatccaggag attgcttagt attaaataat actagagtta
    52921 taccagctag attaatagga gagaagcttg aaactggagg taaaatagag tttttattat
    52981 taaaaagaac agaggaagat acttggcagg ctttagtaaa accaggaaaa agagcaaaag
    53041 tagggactaa attttctttt ggaaatggaa agctaattgg agaagttgta gatttatcag
    53101 atgaaggttc aagaattata aaattccatt atgatggaat ttttgaagaa atattggatg
    53161 aacttggaaa tatgccacta cctccatata tcactgctag actagatgaa aaagaaagat
    53221 accagactgt ttattcaaag cataatggtt cagcagcagc acctacagca ggattacatt
    53281 ttacagaaga attgttaaat aaaataaaag aaaaaggtgt agatatagcc tttgtaactc
    53341 tacatgttgg cttaggaact tttagaccag taaaagtaga ggatgtttta aatcacaaga
    53401 tgcattcaga atattatatg gttagccaag aagcagctga caaaataaat agagcaaagg
    53461 aaaatggaaa aaatgtaata tgtgttggta ctactagttg tagaactata gaatcagctt
    53521 gtaatgagga tggaaagatg aaagaaacta gtggatggac agaaatattt atatatccag
    53581 gttataaatt taaagtttta gataaactta ttactaattt tcacttacca gagtctacac
    53641 taataatgtt agtaagtgct atttgtggaa aggataatgt tttaaatgca tataatgagg
    53701 cagtaaaaga aagatataga ttcttcagtt ttggagatgc tatgattata aagtagggag
    53761 gtaatagatg catagtttac aaaaacaaaa aaagaataac cctatattaa agattgcttt
    53821 tatatttgaa cgtgttttag cagtagtagt tctaatagca gtatttttag gaactataga
    53881 tgttctaaga cttatgtggg gagcatatat agttgatttt caaaatccag tacaatacag
    53941 tcagcttaat gattttttag cacaaatatt acttttagta ataggtgttg aacttgtagt
    54001 aatgctatct cttcatatac caggagcatt tattgaggca ttactttacg caattgctag
    54061 aaaaatgttg ctactgccta aaaatgaagg tatgatagat gttttaatag gagttatagc
    54121 tatagcagga ctatttgcta taaaaaagtt tttagtaaca aaagacaaga gtgctcttaa
    54181 tataatgagt attcatgatg aagaagcaat taaggaacaa cagaacaaag aagacgaaga
    54241 taaatctatt tagacaataa attatatgaa tagcttatta caaatatatc ttaagaaata
    54301 atgagaaata aatatgatta aggagaactt tatgtacgca gtaagatacg aattgataaa
    54361 gacttgtaag cagagtggtg caaggttagg aagattacac actccacatg ggattattga
    54421 aacaccaata ttcatgccag ttggaactca agcaactgta aaatctatga caccagaaga
    54481 attaaaagag attggttcac aaataatact tagtaacaca taccatttat atatgagacc
    54541 aggtcatgaa cttataaaaa gagctggtgg tcttcataag tttatgaatt gggataaacc
    54601 aatacttaca gatagtggag ggttccaggt atttagtcta gggcctttaa gaaagataaa
    54661 agaagaaggt gtagaattta ggtcacactt agatggttca aaacattttc taactccaga
    54721 aaaagctatg gaaatacaaa atgcattggg ttcagacata atgatggcat ttgatgagtg
    54781 tgcaccatac ccatcagata gagaatatgt aaaaaattct ttagaaagaa caacaagatg
    54841 gttaaaaaga tgtaaagatg cccataataa taccgacaag caagctttat ttggtataat
    54901 acaaggtggg atgtataaag acttaaggga acaatcagcg aaagaaataa ctaatattga
    54961 tttaccagga tatgctattg gtggacttag tgttggagaa ccaaaaccac ttatgtatga
    55021 cgtgttagag catacaactc cacttatgcc aaaggataaa ccaagatacc taatgggagt
    55081 tggtagtcca gatgacttag tagaaggtgt tataagagga gtagacatgt ttgattgtgt
    55141 cctacctact cgtatcgcta gaaatggaac tgcaatgact agccaaggta aagtagtagt
    55201 tagaaatgca acttatgctg aagactttac tccacttgac cctgaatgtg attgttatgc
    55261 ttgtaaaaac tattcaagag cttatataag acaccttata aaagcaaatg aaatactggg
    55321 tgcaagatta ataactactc ataatcttca ctttttatta aatttaatga aacaaataag
    55381 acaagcgata atggaagata gattacttga ttttagaaat gaattttttg caaaatatgg
    55441 atatgaaata taggttttgc actattaatt ataatcattt taatatataa tattcaatag
    55501 tactcaaaga tagagaaagt aaattgttat ataaacattt attatgattt acaaaagagt
    55561 ataatttaca aaggagtgaa aaattaatgc cacagcaaca aataattatg agtataggtc
    55621 tatgggtagt agtaatcgca atcttttatt tcctaatgat tagacctcaa aagaaaaaag
    55681 acaaacaatt aaaagaaatg agaagtagcc taagtgtagg agacaaggtc attacaatag
    55741 gtggaatagt agctaatgta gctaaagttg aagatgatgt tgtaatatta gaattaggac
    55801 caaatagaac taaagttcca tttgaaaaat gggctatagg aactgttaaa tctaaaaaag
    55861 aagaaataga agaagactaa attagtaatt taaaagcctt ttctcgaata tatattaatt
    55921 tgagaggagg tttttttatg ggaaaatcta attatatttt taaaggtcta ggatatgcat
    55981 atataataac tttggctgtt ttattagtgt ataacttatt tttgacattt acagatattg
    56041 gtggagataa tataactatg gtctcatcat ttataactac tatttctgca gctataggag
    56101 ggttttacac ttcaaaacac atgaaagaaa aaggacttat gtatgggctt ttagtaggac
    56161 ttttgtacat agtatgtatt tttttgactg tgtttttagc acaagaaaag tttgtatttg
    56221 aagtagggat gatttataag ttattgttaa tatcagcagc aggaggcatt ggaggcgtat
    56281 tgggtgtcaa ctttaaatag agtttatatt aaagtagttt tatgatataa tcaataggaa
    56341 acaattagaa atggaggcgt tgaaaatgga aaataaacat gtaaaaactt tatctcaagc
    56401 tactttaaag caaagtgctg caaaaggtgg atgtggagag tgtcaaactt cttgtcaatc
    56461 agcttgtaaa acttcttgta cagttgcaaa tcaagagtgt gaaagataga aaattattga
    56521 tttagttgtt tgtaagaggg tatctcaaag tgattctttt atcattatga ggtatcctct
    56581 tttattttca attattatat aaaaatatat attctattta tgtaaaatta aatttgattt
    56641 cttatcgttt aattatgcaa aaatatctaa tcatataaga gcatttattt taaagtagct
    56701 actcttatat tttatttttt atcaattaca tgtattagaa taatttttaa ttttaaactc
    56761 taatttatga tgatttttat aatatgttat atattttaat atatggagat agatattaat
    56821 ttagtgatat atatttaagt aataagagta aagcaaaaat tagtgcatag tagtatataa
    56881 aaatggagtt tgaatacttt tgttagtata tgattgttta gtagaaaatc actataaaat
    56941 aggatttcta tctttgagca taattataga gagctaagca gggggaaggg gttcaagaag
    57001 atattattag tgtttgtgtt agtaaattat gtaaacacat aaaatatatt gaaaaataat
    57061 attatatata atattattta tgtgtgggaa atacgaatat aaaaaataaa aaataatatt
    57121 cggaggacat aaatatgtta agcaacaaaa agagaagtat ggcaatagta atggcaggtg
    57181 ctacagttat gagtgcagca gcaccaatat tcgcagacaa tactgtgaca gaaaatgttg
    57241 ataaaaatta cacagtaagt gcgaaagatt ctgctaaact aatcgaagag gttagaaaag
    57301 cattagaagt taagtttgaa gatacaaaag caggagcaaa tgtaaatgat agagtttacg
    57361 atataaaagt agacaatgta aacttaacta atgcaactca attacaaaat aagataaact
    57421 ctttaacaga agggcaaagt ttaaaagtta ctattcaaga taaaggacat caagtgttag
    57481 gtggaaaagt agttgactat aaaattgaaa actacaaaac tgctcaagaa atagtagatg
    57541 cagttaatgc ttacaatgca actttagcag aagattctga taacaagtta acagcaacta
    57601 taaaatctac aaatacagtt gaagtaaaaa gagcaaaaga ttcagcaaat gttattacat
    57661 taaatgtagg agaccaacat ttagatttct caaaagtgat aacatcagaa gaaggtactt
    57721 ttgaaggtta tgaaaagagt tatagtgaca tagattcaaa agaattacat acgataacag
    57781 ttaaaaacgc agatttacaa gacatatcag cagaagaatt atttgatgga attagattaa
    57841 ctacattagg aagagaaata gttaataaag ttaaaaatgg atatgcttta acatttgaaa
    57901 atgaagcaat ccttactcaa gaacaagaag atagtgatga taaagataaa ccagaaaaat
    57961 caagctttga tatagtttta agcaaggcaa atgaaaagcc agaaacaata agtgtttcaa
    58021 gtaaaaacca taagttagtt agagacttac acaaagtatt aactgatgta aaaggtggaa
    58081 aagaattaaa agtagaagtt ttatctggtg attcaagatt tacaacagca gtagaagtta
    58141 gtaaagagag attcaaagat ggagaagcag aagctataat tttagttgga gaagatgcta
    58201 tagttgatgg attagcatca gcaccacttg cctctcaaaa aaatgcacca atattattat
    58261 ctaaaaaaga ttcactacca tcagaaatag aagctgaaat attaagagta cttggaagta
    58321 atctatcttc taagaaaata tatatagtag gtggagaatc taaagtatca aaagaaactg
    58381 aagaaaaact ttctaaatta ggtgtaagta aagttgagag agtttctgga gaagatagat
    58441 ttgaaacttc tttagaaata gcaaaacaat taaaagatac atttaagact gcttttgtag
    58501 taggtggaaa tggagaagct gatgctatga gtatatcagc tagagctgct caatttggtg
    58561 ctccaataat agttacaggt aacgaattag atgcaaatgc tgaaaaatta ttaaaaggaa
    58621 aagaattaga aatagtgggt ggagaaaatt ctgtatcaaa agaagttgaa gacaaattag
    58681 ttgatataga tttaaataat aaagttgaaa gattagctgg agaaaataga aaagatacta
    58741 atgctaaagt aatcaataaa tactatgcag gtgcaactaa agcatatgta gcaaaagatg
    58801 gttatgtagg tggaaatgga caattagttg atgcacttac agcagcacca cttgcagcta
    58861 gttcaaaggc tccaatagta ttaactacag aagaactttc taaatcacaa gaagaagtag
    58921 ttgagttaag acttaagaat gctactaagt tagtacaaat aggtgaagga atagctaaaa
    58981 acgctattga aaaaatagca gaaaaaataa acttatttac taagaactaa taagatatag
    59041 gaattaatat taaaagtttg tttagataat atatgattat acaatgcgtt aatatgtaag
    59101 acatagtgta gatattataa aatatacaaa taacaagata aaataataaa aataaggtgt
    59161 ctcatttaga attagattga gataccttat tttatttttt gattataatg ttgagaaatt
    59221 catattgcaa aaattattat aaaaagatac ttcttataat gattaaacat cttattaaca
    59281 taaattattt tgaacttata acttaattaa ataaaataaa ttataatgtt ttgaatttat
    59341 agagaataaa aactttaggt atattgtttg agttgtatgg ataactatgg tatcatatat
    59401 aaaatatggt aacaaaattg taacttttga ttaaaaataa gtatgagtac taataaaaaa
    59461 tatgaaaagt acattggggg tagaaaataa tatgaagaat agtaaaaaga tattagctat
    59521 aggacttaca ctatttttag taatggtaaa tactcctatg gtaaatgcgt tgacatcagt
    59581 tgagcaaata aaagggaatg acagatatga gacagcagca aaaatagcag ataagcaaaa
    59641 ctacaataca gcaatactaa tcaactcaga taatagctta gcagatggtc taagtgcaag
    59701 tggtttagct ggagccttaa atgcgcctat tttgatgaca aaacaaaatc agattccaaa
    59761 cacaactatg gaaagattaa acaaagcaaa gactgtgtat ataataggct cagaatcaac
    59821 aataagtaaa aatgttgaga atcagttact atccaaaaag aaggttgtac aaagaatctt
    59881 tggtgaaaat agatttgata caagtataaa aatagctgaa aaaatcaaag aaattaagcc
    59941 aatagataaa gtaattatag ccaatggatt tacaggagaa gcagatgcga taagtgcatc
    60001 accagtagct gctagagatg gagtacctat aatacttaca gatggaaata gtgtgggatt
    60061 tgacacgaca ggcttaaaga gttatgcgct tggttctagt gaaataatca gcgacgaatt
    60121 agttaagagc acaaattcta ttagattggg tggcacagat agatttgaaa ctaataagat
    60181 agttatacaa gagttttata aaaatagtaa agaattttat ctaagtaaag gcttacaatt
    60241 aacagacgct ttggctgcct ctacaatagc aaaaaatgct cctgtagttt tagttgaaaa
    60301 tggcagtaac aagagtattt taagtggtgc agacaaattg actgtactag gaggcataaa
    60361 tcagaatgtt atcaagcaat gtataaatca agcttcacca aatcaacaag gtttatatta
    60421 caatccaaat gatagagcat ttaaagagag aataaagggt aaagtatatg ctcttacaaa
    60481 gcagtataga aaagagaatg gagtaagagc gttatctgta gcaagcagat tagagggttt
    60541 agcaaatgat tggtctaatt taatggcaaa taagaagact ttatctcata cgataaatgg
    60601 aaaaaattca tattctactt ttttgaaata cttagattgg agtgagatta aacctggata
    60661 tatagcagtt caaggtgaaa atataattaa atataaaatt ccagataaac ctgtatatac
    60721 aaatagagat gcagatgata taggaaactt tatttttaat gagtggaaga caaatccaga
    60781 agaaggaact aacatgttgc ataaagggta tgaaataatg ggatttggta tagctataac
    60841 aggagataag aatctatatg ctacacatga attttatgga agatataaag aataagaaaa
    60901 tatacacaaa attatgcttg taaggaagct atataaataa ttaaattata atggaaaata
    60961 acatttatat taataaatta atataaatgt tattttttta taatttaatc taaaaaaatt
    61021 gtattaaaaa gtttaaatat agtataaaat gggtaagaaa gtagtgaaaa ttaaatggca
    61081 aaattaggga aatctaatga cgcaaaacta tagggattaa agcttttaaa gccatatcag
    61141 ccagttgcta aaaagagtaa agtcttttta ttttataatt aagattctct ttgagtgtct
    61201 ttttttattg tctgaaactt atagtattta aattcatgaa aaattagata tttattaagg
    61261 gaggattgtt atttcatgaa aaaggcaata tcttgtgtac tagcagtatc tatgtgtagt
    61321 gcaccactaa acgtttttgc agaacctata ttagagggga agctaagggc agttgaaaaa
    61381 tcagttacag aaaagttaag ggggagtctt gaagtagatt taaatttttc actgccaata
    61441 aaaaatagcg attcagaaag tatgactaat atgcagttac gattaaaaga tgatagtaac
    61501 aatagtggaa taataaagct tggagaaaaa gattcaggaa cagtaaatgt tgggacagat
    61561 aatatagaat atactataaa aaaattatct gcaagtagaa gtgaaataaa aaataaagat
    61621 gagaatatat catattataa tattgtattt aataatttac ctgttggaaa atacaatgta
    61681 gaagtctctg gagatggatt taagaacaaa gaaattaaag acattgatat atcaagttat
    61741 tcacaaagag tcttattaag caatagagca agtgtagata ataaaaataa acctttaaat
    61801 tatgaattgt tcttaatggg tgatgtaaat ggagacggta aagtagataa gagtgattat
    61861 aataaggttt tagagaatat agattcaaat aaaagagaat ttgatttaaa tagagatgga
    61921 aaggtagata ttgttgactt agattatgta cagaaaaatt taggacaaag tgaagatgca
    61981 aaaagcctag aaagtatagt atctaccaat cctatagtag atacaagtaa ggttgaatta
    62041 aaaggaaata gtgatgtaga tattaatggt aatgtagaaa atttatttag tggagaaaat
    62101 aatggagtta caatatcttc aaaaaatgat gaaatatctg aggaaaaacc agcagtaatg
    62161 gatatagctt tatcagaagc acttaatatg gaagtcatca atataaaagc tccagaaggt
    62221 actgctccag caaaaggaat agttgaggtt actgacaaag atggtaatgt tcaacagatt
    62281 ccttatgaaa acaaagaata tatgaaaaac ttaaaagatg aggagcaaca agaggaagta
    62341 aataacgaac aagaagaagt aaatcaagaa gaagtaaata ataaagatga aaatataaac
    62401 cagactgata ataactcaaa taataaagat gaaaataatg atgaacaaca ggaaaatagc
    62461 gataaacaag aagtaaactc taataccaat caagataaaa ataatgataa agaaaattca
    62521 tcaatggata aacctaattc agatgaagat actccaaaag aagagggtaa tatcagtaaa
    62581 gatgataact ctacaacatc tacatatagt aagtcaacat tagaaacata tgcagatgtt
    62641 caaaatagtg atatagtaat aaatcttggt aaacaagtag cagtaaaaaa gataactata
    62701 aaaataacag ctacaacagc aaacgataga aatcttgcag aaatatcaaa agttgaattt
    62761 ttaaacaatg tatataaaga aataccaaag ccagagatga atatacctaa aataaataaa
    62821 atatcgacta gcactgctgt tggaaatgaa aaagtatctt tttattggaa taatgaagta
    62881 aatgtatcag catacgaact tatactagat aaaattgata gtaagggaaa agtattatct
    62941 actaaaaaat tacaaaccag taaaaataca atagaagtta gagatataga agcatatgga
    63001 ctatataggg ttagcataca atctttaaat ggagattggt ctagtggtta taaagatgca
    63061 acaccagaaa acttagacgg agtaccagaa aatgtagatt caaactataa acctatacaa
    63121 tttagcccag atagtatatt agaatttcaa gttgttccag acacaaaacc agaaccacca
    63181 gaaggtataa atgttaaagg taaatttaaa tctcttgatg taagctggaa aaatcataaa
    63241 caagctaaag attttgactt gtactataaa gaaaaaggct ctaatgggtc ttggataaaa
    63301 tacaatgata agcttattcg tgggacaagt tcaaagatag aaggtcttaa ggataataca
    63361 acatatgaag ttagaatgac agctactaac cacttgggaa ctagtggaat gtctaaaaca
    63421 tatataggta caactgaaag catggatgca ccaacaacac ctaactatag attaattaat
    63481 actcctaaag agaatggtgg atttggaata ccaacaaatc acattgtaga tgttacttat
    63541 ccagcaggat atgacaaaag tgaatatagt gataaaaatc catttgataa attcaatgta
    63601 gtagatgggg actttacaac acattggaca ttcccaacat ataatgcagc tgagggaacg
    63661 aatagaggac caataataac ttttgataaa tcttatacta tggatacttt tatggctaca
    63721 cctcgttttg atgtttctga taagacaata aatgactttg aggtacgata ttgggatgaa
    63781 aatggtcaat tacacaatct gggggatgtt ccttttgaaa caaagacaga ccctgtaaat
    63841 aataataagt atgtaatggt tagattaaaa gaaccaataa ctgctaccaa gatacaagta
    63901 agtgtttgtt catcctattc atataagtct aatatatcag aacttaagtt ttatgagtat
    63961 gacagtatag aagatgatgt aagaaatcta tttatggatg acctacaagt tgaattaaaa
    64021 gaagatgtaa ctcaagaaaa aataactgaa ttaaaagata gattaaatac tccagataaa
    64081 gctagtggag aatatcatcc atataagaca gttattgaga gagaattaaa attagctcaa
    64141 gacttatata atgatagagc cacacttact gatgtaacta ctgtaaatca agaaataaat
    64201 aaattaggaa aatataaaga taaaaacgga cagtatactg taaattccaa taatttaggt
    64261 atgcaaaatg actggcaggc attaggagta gctgctagag caggagatga aatcacagta
    64321 tatgttggaa gtaaaagtgg aaaaactcct aagttgatat atacacagta ctatggagaa
    64381 tctggtgcat ataagagtgg agaaataaat cttaacactg gaaaaaatgt aattcaatta
    64441 agcaaacttc atagtttaga tatagaatgt ggaggaagtt tatacataag atacgctgaa
    64501 gatactccaa gtggaggaga tataaaagta cgtgtagcag gagctactaa gataccacac
    64561 cttaatctaa atggaacaat aaatgataag agtcctgcgg gagtttctga atctaagaaa
    64621 aagataaaag catatataga agaattagct agatataaag atgctgtaaa aggagaacca
    64681 tattatccag gaacaaatgt tggtaattca tatggatatt cagaaaaaac tggtgtgtta
    64741 aacactacag atattgaaag tgataaagta acattaaatg ttcctgcaac agctgtatat
    64801 caagggatat caaaaggaaa tgctgattta aatacacaag tagatagatt atataatagt
    64861 atgcttgcat gggaacaaat aatggattta gtttactcag aaagaggagt atttaaaaca
    64921 caagatttag atggtaatgg aactgtagat gataatgaat ttaacttaac taaaaatgat
    64981 atggctccaa aatctcgtat gaacataaaa taccaaagaa tgtttattgg agcatttatg
    65041 tatgcttctg gattacatgt aggagtagaa tatggttcag ttccagggct tatgaatgga
    65101 gtacctttcc aaatagatga tagtggaaaa gctacaggag gaaacttatt tggatgggga
    65161 ataggtcatg agataggaca tgttacagat attggaaaga tgacatatag cgaaactagt
    65221 aacaatgtac ttgctttact tgctcagacc tttgatgata agacacattc aagaattgaa
    65281 ggttcaacaa tggataagat atatgagcat gtaacttcaa atagcttagg tataccaagc
    65341 aatgtatttg aaaggcttgg aatgttatgg caattacatc tagcttatga tgatgatttt
    65401 acgggttcaa tgttaaagaa taactcagat gctgatttaa gtaatgatac attctatgca
    65461 aagatttcaa gaaaatacag agcactttca agtagtgacc caattaatag tttgccaaaa
    65521 gaccaaatgc tagtagcaat ggcatcaagt gttgttgaaa aagatttaag agattacttt
    65581 aaggcatggg gagtagaaat tacaccagaa ttaaacagta taatggatag taagaactac
    65641 gaaaaagaat caagaaagat acaatatgta aatgacgaag ctagaagaaa gattttaaat
    65701 gaaaatatag ctagtatggc aaaagatact aaagtaagtg ctagtttttc tgatggaata
    65761 caaagtggtt ctctagttaa atctaataaa atatctatag acctagatgt agataaggat
    65821 aaagataaga tactaggata cgaaataata agaagtgatg gaaattattt agatggtgaa
    65881 aatggaacac aggtaaaata cagaacagtt ggatttgtgg atgcaaaagg aaatagtaag
    65941 actaaattta ctgataatat atctcctctt aataacagag catttacata taaggtagtt
    66001 gcatatgatt atcacctaaa tccaacagaa gaatttgaag ttggtactgt aaaattatca
    66061 gatgaaggga aaataaataa atcagcatgg tcattcataa caaatactgt ttctgacggt
    66121 gatgttagaa ctgaaaatga ctcacatgga ccattacaaa atcctgaaat tgataatata
    66181 aaagataatg atgcaaatac tacatataaa ggaaagataa taagtaaagc agagtggaac
    66241 aaagaccctc aaaaagaccc tgatataaat gtagaggaaa atccatatat aatagtagac
    66301 atgaaagaaa cattacctat agtaggacta aaatatacaa aaccagagac agaagctagg
    66361 aagttctcat taaaaggatt atttaacttt agaaagaata ctagcacaac atacaatcct
    66421 ttaactaatt acaaaataca agtaagtaat gataaaaaga actgggaaga tgtaagtcaa
    66481 ggaacttttg aatatggaca agatttagtt ggtggaggaa aagaccaaga taatgaagct
    66541 agagttacat ttaataaaga tggtaaactt tggacatacc aagctagata tgtaaaacta
    66601 atctcaaata ataagtctaa tatagaagtt gcagaattag atataatagg acctccaggt
    66661 gataatatag aaattggcac aatgaataat gcagacgaaa ctcgtactaa tggaattgga
    66721 aaattagcag aagattatgt atatcaaagt gatgactcta gcacaagtga agatgaaaca
    66781 ggtaagattc cagcgggttc aatagttatt acaggtgaat acagtggaaa tccagcattt
    66841 aatttaccac tacttataga taaaaacaat aagactatat ctggagaagc acttttattt
    66901 gcagaagttc cagaaaaagg tgaactaggt gaaatcagta aaggtacatg ggtttactat
    66961 atgccaaaag aaaactttga ttctttaagt gataaggtta aggctgaact atatagatac
    67021 aatgaccttc aaggagatac tccagtaggt caaagatttg taagtgatac aatgtatgta
    67081 cctgtaggag ctaagaatta tgatgagtta aagacaataa gtcttactga tagtaatagt
    67141 aaagctagaa aagctacaag aaattctatt gatatcagta ataagaaggt tataactgta
    67201 agcaataaag taaagggtaa tattgttaga gataaatagt aggtggaact ctaaaaacgt
    67261 aaaaatacta acactaacat tgtatatcta ataagattag gtactagaat agttttaaaa
    67321 tagtagatat taaaagtaaa gtatataaat gtaatcataa atttagggta atttataaat
    67381 taaatataaa agctaggtgg ataagtaaat ttatccactt agttaatgat agataaggac
    67441 gggtgttaat gagtaaaaga aaatctttta taagaactat agcagtatca actatggcag
    67501 tagctgtaac tggtagtgct acatgtgcat atgcagctcc agttttacaa ggaacaaaaa
    67561 cgtatgagaa agtaaatact atagatatat ctgtggactc agtagaaaac atagtatatt
    67621 catttcaagc cagtataaaa gtacaaggtg aggttgaagt agtagataat gagcagaaag
    67681 aaaagattac ttggtctgat aatataaaat ctcagataaa aagtggaaat gcaaatgcta
    67741 cttgtagagc agaatacaac aaatcaagta atacaactac attagatata tatgttacat
    67801 caaatgaaga cttactagac ggaaatagat tgaatatagg aagaatatct gtaaaaaaat
    67861 ctggaagtaa ctcaaatgct gactataaag ttttaggaaa aggaacaaat gataaaccag
    67921 ctttaaaaat tgtaacatat aacaacaaaa cagtggatta tgaaaatata agctctgatg
    67981 aaggattaat atttaccctt attaatgaga gtgaagtaaa accgattggg ggaactggtt
    68041 ctagtaaaaa tgaccctgaa aagtataagg tagagaaaag tgaagcactt gaatatttat
    68101 taaacaatat taggataaac tattctattg ttagtaaaga aacacaagaa agtggttcaa
    68161 atgtaatatt aaaacttgga ttagcacaaa aaacaactaa gggaagaaaa gttacaataa
    68221 acaaatatgt tgaagttaca cttccaaaaa gtttagaata catagttgaa aatgaattat
    68281 caaaaccgga tgaattacca ccagataatg gtagtggtgg aaataatggt ggaggaagta
    68341 attcaggcgg ctcatctagt ggtggaagct ctggaggagg aaattcaagt gattctacat
    68401 ctaatgtcac agtcaaaaaa ttaaaaggtg atgatagatt tgagacagct atcaaaatat
    68461 ctcaaagtgg ttggacaaaa tcagatacag ttgtaatagt aaatggagaa gataaaagta
    68521 tggtggatgg gcttacagct acaccacttg ctagtgtaaa aaactcaccg attcttttat
    68581 catcaaatga taaacttcct caaaaaactg tagaagaatt gaaaaggcta aatccatcaa
    68641 aagtagttgt gataggtgga aacaactcaa tgccaaattc agttgttgaa gctatcaaag
    68701 ctgtaaattc aaaaatatca gtacaaagaa taggtggaga tacaagatat caaacttcta
    68761 ttaatatagc aaaagaaata gataagacga ataatgtaag caagttgtat ataggagcag
    68821 gaaatggaga agctgattca ttatcaatag catcactggc tggtaaagaa aaaactccaa
    68881 tagtacttac acaaaaagat ggtgtagata atgaagctga acaatttatt aaatcaaata
    68941 aggtgtcaaa tatatatttt attggtggag tagaaaaaat atctaacaag gctattgaac
    69001 aagttggaaa aatagcaaac aaagatatat caaacaatag ggtggcaggt caaactagac
    69061 aagagacgaa tgccaaagta atagataaat tctactctca atctaagcta gatggagttg
    69121 tagttgcaaa tcaagataaa cttatagatg ctttagcagt tggaccatta gcagctaaaa
    69181 acaattcacc agttatactt gctacaaata cgttagataa atcacaagaa tcgtcattaa
    69241 aaggtaaaaa ttcatcaaag ttgtttgaag taggtggagg aatagcctca tctgtaatag
    69301 acaagattaa gagtttaatt gaaaaataaa tattaagtaa atagaaaata agaatgtatt
    69361 tagatataaa gttatatatt taaatgcatt cttattttat tttcattatc ttaacaatct
    69421 aataatattg aggttaaaat gtataataat ttgagctata ttaagtttaa ttttaaataa
    69481 agcagatatc ttttatatat ataaatataa attcaatttt gaatatgttt aaaaagaagt
    69541 taaaaataat tttttaaatt taataaaata aaacactaat atatagacga gatatattca
    69601 tatcatatat actctataat atatggaaaa taaagagaaa ataaatggaa aataatcaca
    69661 atataaatat aaaatataaa aatcatcagg gggatatgaa aatgaacaaa aaaatattat
    69721 cattaggtct agcagtatca ttaatcttag taaacttcaa aagtgtaaat gcatcatcag
    69781 tagtagaaaa aatatacggt aaagatagat atgaaacagc agcaaagata gctgataaac
    69841 agacttatga aacagtaatt ttagtaaata cagaaaaatc acttgcagat ggattaagtg
    69901 caagtggatt atcgggagct acaaaagctc caatactatt tacacaacaa aataagatac
    69961 cagcagacac aaatagatgt ctaaaaaata tcaaaaaagc atatataata ggtacagaag
    70021 atactataag taaatcagta gaaaaagaac tagattctaa aaatatagaa gtcaaaagaa
    70081 ttggtggaga agatagacta aaaacaagct atttaatagc taaagaaata gcaactataa
    70141 aaaaagttga taaagtacta ctaactaatg catatagtgg agaagcagat gcaatgagtg
    70201 tatcatcagt agctactaga gatggagctc caatcatact tacagatgga aagagtgtgc
    70261 cttttgatgt aaaaaatatt caatcatatt gtataggttc agaggagata atgagtaatc
    70321 ctctagttaa aaatacaaac tcagtaagaa tagaaggaac tgaccgattt gaaactaaca
    70381 aaaacgtaat agactacttt tttaatagtg cagatggatt ctatgtatca gatggatacc
    70441 aattagtaga tgcaatagca gctgcaccac ttactaaaaa ctctccaatg gtactagtaa
    70501 atgatggaag cgataaaact gtattagaag gagctaagaa tataacctct gtaggtgaaa
    70561 tagatgagaa ggtaatacaa caatgtataa gtgcttcaaa gtcaaatgga caacccccag
    70621 caattacagt tggaagtaca gaggtatata agggtgaaaa gtttgacact ggcaagttaa
    70681 atatagtagc taaagataac actgggaagg tattaccaat agaagttgat gggtttatag
    70741 atacaaatag agtaggtaca tacatattga cattaaaagc tacagacgaa tggggaaaaa
    70801 gtacaggaaa aagagtagaa ataaaagtgt tggatgataa atctcatgat tacaacagcc
    70861 cagaatttaa aaaaatggta tctactgaaa tgtataactt aatcaattcc tatagaaaag
    70921 aaaaaggtaa agagcctttg gtagtatcta gtaagctaga aggtatggca aatgcatggt
    70981 ctaagtatat gatggataac aaagtttttg aacattatat agatggcaaa aatgctccac
    71041 aagtattttc tgagtttgga atgagaagtg aggaaaatat agcatatatt tatatagatt
    71101 ctaagagtgt tcaaacaact caagatgcaa aagacttggc aaaggctata tttgaagtgt
    71161 ggaagaaatc tccagaatac aatgcaaaca tgcttagtga tgagttttat agtactggat
    71221 ttgggcttta tatattatct gatggtcaag tgcatgctac tcaagagttt ttaaatggca
    71281 atgaaggtag cttgtaaaaa attccataaa tcttgttttt ttgttaattt actgatatta
    71341 taaaatgaaa atcacatcta aagtactttt tgtaatctgt tttattattg ctttacaggt
    71401 tatggtattt taggtgtttt ttgttttagt agtttataaa ttttgaggga atcactactg
    71461 agggtgtaat ttatgattag ctgaattata taaaaaaatt agtaggagga gttcgatgaa
    71521 ggtaaataag agagtattat caataggatt gacaatatca ttaataatgg caggagcacc
    71581 aaatatcaat gcactttcga gtatagaaaa gatacaaggg aaagatagat atgagacttc
    71641 tgcattgata gcagataaac aaatatatga tacagtcata ttagtaaata ctgataattc
    71701 tatagtagat ggattaagtg caagtggatt atctggagtt gtaaaagctc ctataatgtt
    71761 agtgcaaaga gataagatac caacagatgt tgaaaaaaga ctaaaggatg ttaagaatgc
    71821 ttatgttata ggtacagagg atacaatagg taaatctgta gaaaatcaac ttaagaataa
    71881 agggattgaa gttaaaagaa ttggtgggga agatagaata aagactagct atcttatagc
    71941 taaggagatt tcagctatta aaccagtaaa tgatggtgat aaggtttttc ttgtaaatgg
    72001 atacacaggt gaggctgatg caatgagtgt atcttctgta gctgctagag atggagttcc
    72061 tgttatactt actgatggaa agagtatacc atttaaggtt gatggcgttc aatgttattc
    72121 tcttgggtca gaggagataa tgagtaatga acttgtgagt aagactaatt ctgttaggat
    72181 tgctggtaaa gatagatttg aaactaataa gaaggttata caacgctttt ataaaggaac
    72241 aaagaagttt tatgtttctc aagggtataa gttagttgat gctgtggctg gttctccgtt
    72301 ggctaaggac aaacctatag tacttgttaa tgatggaagt gataagagtg tgcttagagg
    72361 tgctgatgaa gttacttctt taggtggaat ggataagaag gttgctgacc aatgtattag
    72421 ttctgcatct gataaaaata caatgcctac aatcactgct aatgatgtag agatttctgt
    72481 aggggataag tttgataata gtatgttgaa tatagttgcc actgattatt atggaaataa
    72541 tttgaagcct aatattgagg gaactgtgga taccagtaag gcaggaacgt atgttttaaa
    72601 tgtaagtgct tttgataatt ttgggcaaaa gtgtgagatt aatgtaaatg tcaaagtaat
    72661 tataaacaca agtacaaaag accctaatag ttatgagttt aaggctatgg tatctaatga
    72721 aatgtataat ctagttaatt catatagaaa agaaaaaggt aagaaaagtt taagagaatt
    72781 agattcttta gctggaatgg caaatgcatg gtctaagtat atggatgaga agaagatatt
    72841 tgctcatgaa atagatggga aaaatgcagc tgaagtattt tctggctttg gaatgagaac
    72901 tgatgaaaat attgcatatt tacctatgaa tgttaagtct gtatatacat ctaaagatgc
    72961 aaaagagatt gctaagtctg tatttgattt atggaagaag tcttctaagt ataatgataa
    73021 tatgttaaag gaagagtttt atagttttgg ctttggaatg tatgtttcta atcaaagaga
    73081 agttaatgct acaatggaat ttttaaatag ttagagtata tattaatatt ttatggtaga
    73141 aaatattaat atatattgat taaatcagat aaataaatgt attaataaaa ttaaaattga
    73201 aaatttaatt taaaaaatat gaaatagcaa aaaaaagggg aaaaatgttg aaagaaaatt
    73261 ctattaattt tgcataaatt attgaaattc tattttatat agtctatcat aagagtgtga
    73321 gaaatatttg gtttatatga acatggaatt ttaatgtaca taattaaaga gatgtaatta
    73381 atataatgtt gggaggaatt taaggaatga ataagaaaaa tttggcagtt gtaatgtctg
    73441 ccgttacagt aatcggatca gcagcaccag ttttcgctgc agcagaggat agttttccaa
    73501 atggaaatac cactgtatct agtagtaagt atagtgatat agaaagaata cttaaaaaat
    73561 atgttgcaga tggtgtaaca ggcataacag ttaacttttt tgacaaaaaa ggaaatccaa
    73621 aaggggtatc tatatcaagt ttagaagcaa gtcaaataag ttatgttaaa gatgaaatta
    73681 aagatttaaa agctggagaa tatgcaaaaa tatctgtaaa aattacagat ggaacagaaa
    73741 aaaaatatga tgatacatta ttaaaggaac ttgatagtaa tgctgtagtt actaaagttg
    73801 gtactgcaac aacagttaag attgtagatc aagatggaaa ttcaatagaa aatgatgcta
    73861 aattaaagtt acaaaaatat gatacaacta cgtcagctta tgtagatgga gctactaaag
    73921 atgaagtttt agcagctaca aaggcagcag tcaaaacttc aaaatttact gataagactg
    73981 gtaataatgc tacaggaaca gtagctatta cagcaacata tgctgatgca gtagctggtg
    74041 caattaaatt aaaatatgat acacaagcag cagtagcacc tactttagat acagcagtag
    74101 catctcttga tggtactaaa gagatatatg attttagtaa accagttata acggttaata
    74161 ctactgatgg tacatcaaaa ttaagttttg aaaaaactgg agaaaaagtt ggagcagttg
    74221 aatcaaatgt aacagttata gcagcatcag atgaaacagt tacaatatct ggagatgcaa
    74281 aagaaaaagc agaagcttta gctaaaaaat atgtatttaa agatactgaa ttagaagatg
    74341 catataagac agtaacagca agtgattttg aaaaaactga caatgattat tatgaggtag
    74401 ttctttatcc aacaggtaaa agattaaata cagcttcaac atatgcatca tctaactata
    74461 agccagaatt acctacaagt gatagagtag atactcctgc tataataaca ttaagatcta
    74521 ctaataagaa taacttaaaa tcagctttag atgaattaag aacttataat aattcttatt
    74581 caaataattc tgtattagct ggtgatgata gaatagagac tgcaatagaa ataagtaaag
    74641 actcttataa tgcagatgga ggaattaaag gagattatgt agaagctaat gaggtagtat
    74701 tagtaggatc acaatcaata gtagatggtc tagtagcttc acctttagct gctgttaaag
    74761 atgctccatt attattaact tcaaaagata agttagattc atcagtaaaa tctgaaataa
    74821 agagagtaat gggattagat gataaaactg gtataacatc taaaaagact gtttatatag
    74881 ctggtgggga aaattctgta tctaaagaag tagcaaatga attaaaagat atgggattaa
    74941 aagttgaaag attatctggt gatgatagat atgctacatc tttagaaatt gctgatgaaa
    75001 taggtttaaa ccataataaa gtatttgtag ttggtggtac tggattagca gatgcaatga
    75061 gtatagcatc agttgcttct aataaagaaa tgccaatagt agtagttgat ggaaaaggaa
    75121 aagatttatc aactgatgca aaagacttta taggaagtgc ttatgtagat ataataggtg
    75181 gaaaatctag tgtttctgaa gacatggaag atgctataga tgatgctaca ggtaagagtc
    75241 cagaaagagt tagtggagat gatagacaag atactaatgc agaagttata aaaacttatt
    75301 ttgaaaaaga taatagtgac agtgtaatta gcacaggtgt taaaaacttc tatgttgcta
    75361 aagatggttc tacaaaagaa gatcaattag tagatgcgtt agcaatagca gcagtagcag
    75421 gtcacaatga agctccaata gttttagcaa ctgatagttt atcttctgac caatcagtag
    75481 caataagtaa agttacaaat tctgatgatt ctaagaaatt gactcaagtt ggtaaaggaa
    75541 tagcagattc agttattaag agaataaaag atttattaga attataagat aaaattaaac
    75601 tataaataag agggaacttc tttgaagaag ttctcttttt tataaaaaga aattaaaaaa
    75661 ggaactaaaa atagttcctt tttttgtgag aaatacctaa ataattaaag atgtaattta
    75721 tttaagtatg attattatac tataaataaa aataattgtc tactattcta taattttaag
    75781 gtataatagt aattgtatga taaaaaagga ggtaaattaa atatgtcagt tttggataca
    75841 atattggata aagcagatga gcaggaaata agaaggctta atgtgatagt tgataaaata
    75901 gaatctttag aaaaagatat agaaaatatg tctgatgacg aattaaaaaa aatgacagac
    75961 ctatttagag atagattaaa aaaaggagaa actttagata gtttattacc agaagcattt
    76021 gcagtggcaa gagaagcttc aaaaagagtt ttaggaatgc gtcaatatag ggttcaatta
    76081 attggaggca ttgtaattca tcaaggaaaa atagcagaaa tgaaaactgg tgaaggtaaa
    76141 actttggtag aagttgcacc tgtttatcta aatgctttaa caggtaaagg tgtgcatgtt
    76201 gttacagtaa atgactatct agcacaacgt gataaagagc taatgcaacc agtgtatgag
    76261 tttttaggta tgtctgtagg agtaattatt gcagatctta tacctgaagt tagaaaagtt
    76321 caatacaatt gtgatattac ttatggtaca aataatgaat ttggatttga ttatttaaaa
    76381 gataatatgg taactaaaaa gtttgataaa gtacaaagag agttgaattt tgccatagtt
    76441 gatgaggttg actcaattct tatagatgaa gctagaactc cacttataat tgctggagag
    76501 ggtgatgaag attcaaaact ttatgaatta gcaaattcat ttataaaaac aataaaagaa
    76561 gaagattatg aattagatag aaaagataag accgtagctc taaaggaaag tggtattgat
    76621 aaggcagaat cattttttgg gattaaaaat cttacagata tagaaaatat agaattatat
    76681 catcatataa atcaggctct taggggtcac aaacttatgg aaaaagatgt tgattatgtt
    76741 gttgttaatc aagaagtaat gatagttgat gaatttacag gaagagtaat ggatggaaga
    76801 agatatacag atggcttaca ccaagctata gaagcaaaag aaggggtaga aataaaagat
    76861 gaatctaaaa ctatggctac aattacattc cagaatttct ttagattata taataaactt
    76921 tctggtatga cagggactgc taaaactgaa gaaggagaat ttgaatcaat ttataaatta
    76981 aatgttgtac aaattcctac taacaaacca attataagag cagatcttca tgataaagtg
    77041 tttagaacag agaaagaaaa gtatcaagct gttgtagaag aagtaataag gatacataaa
    77101 acaaaacagc caattcttat tggtactgtt tctgttgaga aatcagaaat gttatctggt
    77161 atgcttaaga aagaaggaat aaaacatcaa gttctaaatg ctaaggaaaa tgataaagaa
    77221 gcattgatag tgtcaaaggc tggtaagttg ggttcagtaa ctattgcaac taatatggca
    77281 ggtagaggaa cagatattgc tttaggagca ggtgataaag aagaagaaag tagagtaaag
    77341 gaattaggag gactttatgt aataggaact gagagacatg aatctagaag aatcgataat
    77401 cagcttagag ggcgttctgg acgtcaaggt gatccaggaa catcaaggtt ttttgttagt
    77461 cttgaagatg atgtaatcaa attgtatggt ggaaaaagta tagagaaact aatgaaacga
    77521 ccaaattcaa ataaaaataa ttctattgaa agtaaatctc ttacaaaggc aatagagaga
    77581 gctcaaaaag gggtggaagg taaaaatttt gaattaagga aaaatgttct taaatatgat
    77641 gatactataa atgaacaaag aaaagtaatc tataacgaaa gaaataaagt tctaaatgat
    77701 gaagatatac aagtagatat tcaaaacatg gttaaagata taataaaaga agctgctgct
    77761 gaatatttaa caaaaagaaa gagggattac tatggatatt ttaagcatct ttataataca
    77821 tttatgccag ctgatacctt actaatacct gacttagata ataaaagtat tgaggatata
    77881 attgatagta cttatgaaat atcaaaaaga gtttatgatt taaaaaagat ggtagtaggc
    77941 cttgacaaaa taaccgaaat ggaaaaaatt gttcttttaa aagtagttga tcaatattgg
    78001 gtagaacata tagatgctat ggagcaatta aaacaatatg taggatttaa atcatatgct
    78061 caaaaagatc ctttcaaaga atatgctatg gaaggttatg agatgtttga atcattaaat
    78121 aaaaatataa gagagacgac tatacagtat ttatataaat ttaattaaga aatttaaact
    78181 gtataggaaa aagaggctga taatcagcct ctttttctat gtgagaaata cggaaaaaag
    78241 agatgcttga aatttctttc ttccatttaa tattatacta taaagaagat gaaaagtcta
    78301 ttagttataa actggattat taaaaaaaat tacaattttg ttactttttt gtatacgtaa
    78361 atattaaaaa aataaaatat aagaaaaagt ttatatcttt tggttaatta ttacaataag
    78421 tctcatttat tgaaataata tcaaatatat attataattg gtaaataagg aaaaaataat
    78481 aaaaatttga attttttagg gggaaaatac catgaataaa aaaaatcttt ctgtaattat
    78541 ggctgctgca atgataagta catcagtagc tccagttttt gctgcagaaa ctacacaggt
    78601 aaaaaaagaa acaataacta agaaagaggc tacagaatta gtttcgaaag ttagaggttt
    78661 aatgtctcaa aagtatacag gaggttctca agttggacaa ccaatatatg aaataaaagt
    78721 tggtgagact ttatcaaaat taaaaataat aactaatata gatgaattag agaaattagt
    78781 aaatgctttg ggagaaaata aagaacttat tgtaactata acagataaag gacatataac
    78841 aaatagtgca aatgaagtag ttgcagaagc aactgaaaaa tatgaaaatt cagcagacct
    78901 ttccgctgag gctaattcta taacagaaaa agctaaaact gaaaccaatg gaatttataa
    78961 agttgcagat gtaaaagctt catatgatag tgctaaagat aagttagtta taactttaag
    79021 agataaaaca gaaacagtaa cttctaaaac tatatatgta ggtattggtg atgaaaaagt
    79081 tgatttaaca gcaaatccag ttgattcaac tggaacaaat ttagaccctt ctgcagaagg
    79141 atttagagta aataaaatcg ataaactagg tgtagcagga gctaaaaata ttgatgatgt
    79201 ccaattggcc gaaataacta taaaaaatag tgacctaaat acagtttcac cacaagattt
    79261 atatgatgga tatagattga ctgttaaagg taatatggta gcaaatggta catcaaagtc
    79321 aattagtgat atttcagcaa aagattcaga aacaggaaaa tataaattta ctattaagta
    79381 tactgatgca tctggaaaag caacagagct tactgtagaa agtaccaatg aaaaagattt
    79441 aaaagatgcc aaagctgcat tagaaggtaa ttcaaaggtt aaattgatag ctggagatga
    79501 tagatatgca actgcagtgg ctatagcaaa acaaacaaaa tatactgaca atatagttat
    79561 agttaattca aataaactag ttgacggatt agcagctaca ccacttgctc aatctaaaaa
    79621 agcacctata ttattagcat ctgataatga aataccaaaa gtaactttag attatataaa
    79681 agatataatt aagaaaagcc catcagctaa aatatatata gtaggtggag aatcagcagt
    79741 atcaaataca gctaaaaagc aattagaatc agtaactaag aatgttgaaa gactagctgg
    79801 agatgataga catatgactt ctgtagcagt agcaaaagct atggggtctt ttaaagatgc
    79861 atttgtagta ggcgcaaaag gggaggctga tgctatgagt atagctgcta aagctgctga
    79921 acttaaggct cctataatag taaatggttg gaatgatcta tcagcagatg ctatcaaatt
    79981 gatggatgga aaagagattg gcatagttgg tggctctaat aatgtatcta gccaaattga
    80041 aaatcaactt gcagatattg ataaagatag aaaagttcaa agagttgaag gagaaacaag
    80101 acacgatact aatgctaaag ttatagaaac atattatggc aaattagata aactatatat
    80161 agcaaaagat ggatatggaa ataatggtat gctagtagat gcattggcag caggacctct
    80221 agcagcaggt aaaggtccaa tacttctagc taaaactgat ataacagact cacaaaagaa
    80281 tgcacttagt aaaaaattaa atcttggtgc agaagtaact caaataggta atggagttga
    80341 attgacagta atacaaaaga tagctaaaat actaggttgg taataactta tactgtggag
    80401 aagattcctt aattaataca ggaatctttt tctataatta tgctatttat tgtaaattat
    80461 aacattttat aaagtaggag gatgtagtag tggtagatgc aactttgttt tttacaccac
    80521 atcaagatga tgaaacctta agtatgggaa gtgctataat tgaacatgtt gaaaaaagtg
    80581 atacacatgt catattgtgc acagatggta gtaaatctat aataagaaaa gttttggatg
    80641 atggagggtc atgttcttat catattaaag atgttcataa atactcttta tcagaaagtg
    80701 aattttcaaa agatagagat gaagaattta aggatagctg tgaagcaatg ggtgtaaaag
    80761 aaagtaatat acatatagaa gataatagag ctcatgatgg tgagttaagc aaagaaaagg
    80821 caaaggaaat aatacttaaa tacttagaag aatatccaga agcaaaagta aaaactgtta
    80881 ctccgtttaa agctagtgga atacatgaag atcatagagc attaggagaa gctgcactag
    80941 agttatatag agaaggaaaa ataaaagatt taagatttta tgtagaacca tatgactata
    81001 aggattttaa aaaagttaat ccaaatgtag aagtctggaa ggtattacct agtcaagagg
    81061 agaagttatt aagtgcgatg aatgcatata agaaatggaa tcctgaaagt ggacattatg
    81121 ctataggata ccattcagta aaatctcatt ttgatgattt agaattaaat aaaacacagt
    81181 atgtacatgc tccataaaat tatatttaaa ttaggaggag ataattaatg caaatatcaa
    81241 aaaaaataat atctttatta acagcagcat ttttatcaat tgttttacct agtaatgtgg
    81301 taaatgcatc taataaagac agtttaatag gttcaggtag atgggaaaca gcaataaaaa
    81361 taagccaaaa cggttggtta agatctgata atgctgtatt agtgaatgat aactcaatag
    81421 cagatgcatt atctgcaact ccatttgcta aattgaaaga tgcacctatt ttactatctg
    81481 gaagtaaaga attggatttt aggacaaaat cagaactaaa aaggcttgga gtaaaaaatg
    81541 tatttttagt aggaggttca aatgcactag gtgtaaatgt agaaaatgaa ttaaaatcag
    81601 agaaaataac agttgaaaga atttttggga atgatagata tgaaacatcc ttaaaattgg
    81661 ctgaaaaatt gaataatgaa aaagatattt ctgatataat tgtagtaaat ggagaaaagg
    81721 gattagcaga tgctgtaagt gttggttcaa tagcagctca aaattacatg ccaattatac
    81781 tttcagattc aaaccttgga gttgaagtag ctaataaatt tataaaagcc caaaatataa
    81841 aaaattctta tattattgga ggattaaatt ccatttctaa tgaaatagaa aaaaatttac
    81901 caaattctaa gaggatatca ggaaataata gaaatgaaac aaatgctaat gttataaaag
    81961 aattttataa agaaacagat ttaagaaatg catatataac caaggatgga atgaaaaaac
    82021 aaagtgattt aatagattca ctatcagttg gagtgttggc tgcaaaaaac aattctccag
    82081 tggtattagt aggaaataaa attgattcta ttcagaaaga tgtactaaat actaagatat
    82141 ttagtacagt tactcaggtt ggtggaatag gaaatgaaaa tgtctataaa gatatattgg
    82201 atatgcaaga agaaactaaa tatacagttg aaacaattga agaattggat tctgctttaa
    82261 agaaagtgga tgctaatgat attataaagt ttagacctga taaaaaaata agtgaatctt
    82321 ttaaattaga gactgaaaaa gctataaagg ttgatttata tggagaatat agtcagtcaa
    82381 taactataaa tatgccaaat ggagagttga ataatacagg tgatataagt aaaacattga
    82441 tacttaaaga tataaaagat ggaactttaa ctaattcagg atatataaat caaatggaca
    82501 tttctgatga taatggttgc aagattgaaa atgaaaataa tggacaaata tggattgtaa
    82561 caatatttag ttctgcaaaa gatgtaaata taagaaatga tggaactata acaaagatag
    82621 ataatgattc ttcaagtact aatataagaa attcgggaaa gattgatact gttagtggaa
    82681 ataaagaacc aggaataagt ggcaataaac ctaacactaa taatacagat aaagatgatg
    82741 atagtgatac agcagcagga ttatctccaa agataagtgc atgttctcct cttgagaata
    82801 atcaaattat gttaactgta cctcagaaac ctaaaaattc aaattataaa atttattata
    82861 gagttttgtc atataaacca tcagctatga gggttggtga tagaattaac ataaatgatt
    82921 gggacttggt tgaagatacg gaaccattaa aagtaaatgc taagaatgga tcatatatag
    82981 aagttgttga aattgattat acaagaaaga aagtttcaag atggggaaga gctggtgcga
    83041 cagatgatgg ttttaaaata gtagcaaatg gaataaaatc aactgtttct gttgatgaaa
    83101 attctaaagt aactattagt gtaactggat acaatggtaa taaagtttac tatagaataa
    83161 agactacaaa accagaagct atgaatgtag gagatgaaat agactccagt tggaaaagta
    83221 cttctaatag tgatataatt ttagaaggaa ataaggtaaa tggactttat gtagaattag
    83281 catcaggaga aaataataaa gttgaaaaat ggggagcaac agataaaata gaaattgttt
    83341 cttaaagcta ataaggagtt gtttttttta ggcaactcct tattctgcat aaagataaat
    83401 ataataatgt taatttctat gcttaaaaac tactaccttg ctgaagacga agtttaaaat
    83461 tatcacaatt atattagtgc ctatttttac taagatatca tttaaagaaa ataaatcaat
    83521 cattaaatac ataagtaata tttctataaa accagaaaat aaacgacaag ataaaaaaga
    83581 tacaaattct tttaatagaa ataaaaactc agttttttca cttttgaata caaaaaattt
    83641 gtttgttata tatgaaaata aaactgctat agaccaagat agagagtttg ataataaaaa
    83701 agtaaaatta ataattcttg taaaaaatag gtaagtaata atgtttatta aaactgttaa
    83761 agcaccaaaa aaaagatata atattgtttc tagatgtttt tttaatatca aaaaattttc
    83821 ctccattatt tggtatatat tattatgtaa ttagtatacc acatattaat caataaatat
    83881 gcagtataaa atagtatttt atatatgtat aattataatt cctattttta taaaaataaa
    83941 atatgaccta gatttagaaa tctgatataa taaaaattaa atacatacaa gggggtaaat
    84001 atgagaaagt ataaattaaa aaaattgtca aagctactgg tgttgttgac agtttgtttt
    84061 ttaattgtgt caacaatacc tgtctcagca gaaaaaaata aaattctgac tggagtagaa
    84121 actgcagagt attctgaatc atatcttcaa tacttggaag atgtaaaaaa tggagatata
    84181 gcaaaatata atggagtaat accaactcct tatgaaatgg aaggaacaac acttaaaact
    84241 aatgtaagaa gtagtcttcc agcatcatat aaatcaagtg tatcatatga tccaagaaaa
    84301 ttagatttaa ctacaccagc aaaagaccaa ggaaaactta atacatgttg ggctttttct
    84361 ggaatgtcaa cactagaagc atatttgaaa ttaaaaggtt atggaactta tgatctttca
    84421 gaagagcatt ttagatggtg gtcaactgga ggaatacatg gatggaactt aactgatatg
    84481 acaggtagtt cgaatgtaac tgcaattgga tatcttacag cctgggcagg acctaagctg
    84541 gaaaaagaca ttccatataa ttttaaatca gaagatgaag gagcaactag gcctcaaaat
    84601 atggatactg cacctacaca atttaatgta acagatgttg taagaattag taaagataaa
    84661 acttctgtta aaaatgcaat aatgcaatat ggtgcagtga catcaggata tgcacactat
    84721 tcagcctact taagtgatga tgaaaattcg tataattgta atgataaaag tgaaccttta
    84781 aatcattctg tttcaattgt aggatgggat gataattatt caaaagataa gttcaaacca
    84841 agtgttagac cagaatcaaa tggagcatgg ttagtaaaaa gtagttgggg agaatttaac
    84901 tcagaaaaag gctttttctg gatttcttat gaagacaaaa ctcttttaaa agatacagat
    84961 aactacgcaa tgaaatcagt atcaaaacca gatagcgata aaaaaatgta ccaacttgaa
    85021 tatgctggtc ttagcaagat aatgtcaaat aaagtaacag cagcaaatgt atttgatttt
    85081 agcagagatt ctgaaaaact tgactctgtt atgtttgaaa cagattctgt aggagcaaaa
    85141 tatgaagtat attatgcacc agtagtaaat ggagttcctc aaaacaattc aatgacaaaa
    85201 cttgcaagtg gaacagtatc atattctgga tacataaatg tacctactaa ttcttacagc
    85261 ttaccaaaag gtaaaggagc aatagtagta gttatagaca acacagcaaa tcctaataga
    85321 gaaaaatcaa ctttagcata tgaaactgat atagatggat actatctata tgaggctaaa
    85381 gcaaacttag gtgaaagcta catacttcaa aacaataaat ttgaagatat aaatacatat
    85441 agtgaatttt ctccttgtaa ctttgttata aaagctataa caaaaacatc ttctggacaa
    85501 gctacttcag gagaatcttt aactggagca gatagatatg aaacagcagt taaagttagt
    85561 caaaaaggat ggacttcttc acaaaatgca gtattagtaa atggagatgc aatagtggat
    85621 gctttaacag ctacaccatt tacagcagca attgactctc caattctttt gacaggaaaa
    85681 gataacttag attcaaaaac taaggcagag ttacaaagat taggaactaa aaaagtttat
    85741 ctaataggtg gagaaaattc tttaagcaag aatgtacaaa ctcaacttag taatatgggt
    85801 atatcagtag aaagaatttc aggtagtgat agatacaaga ccagtatatc tctagctcaa
    85861 aagttaaata gtataaaatc tgtttcacaa gttgcagtgg caaatggtgt aaatggactt
    85921 gcagatgcaa taagtgttgg tgcagcagct gctgataaca atatgccaat aatacttact
    85981 aatgaaaaga gtgagttgca aggtgctgat gagtttttaa attcatctaa aataactaag
    86041 tcttatataa ttggtggaac agctacttta tcatcaaatt tagaaagtaa gctttcaaat
    86101 ccaacaagac ttgcaggaag taatagaaat gaaactaatg ctaagataat agataaattc
    86161 tatcctagct cagatttgaa atatgctttt gttgttaaag atggttcaaa gagtcaagga
    86221 gacttgatag atggactagc agtaggagca ttaggtgcta aaactgattc accagtagtt
    86281 ttagttggaa ataagttaga tgaaagtcaa aaaaatgtac ttaagtctaa gaaaatagaa
    86341 actcctatta gagttggtgg aaatggaaat gaaaatgctt ttaatgaact aaatactctt
    86401 ttaggaaaat agtgaatgga aagatagtaa ggatatacat tttattatta aaaaatattc
    86461 aatagaagtt tataaatata aaataacaaa acggggtgtc tcaaaatgaa ctttttagtt
    86521 catgaggcac tcttttttgt tgttttatat ttttatcatt taaataatga aaaataggat
    86581 tgtctatatt tttagatagt tttcttatta ttgatgaaaa atgtaataat tttaaactgt
    86641 aaaatagtgt aaagttattt tataatataa atatagtaag attttaaaca aaataagggg
    86701 gaataataat gaaagcacca aaaactattt taacaatact gacaatagcg cttactttaa
    86761 gtagcatttc tataatacca tcatatgcac ttacagagga aaaattaata ggtaatggta
    86821 gatatgaaac tgctgtaaag ataagtcaaa aggcatacag ttctagtcct aatgtagtgc
    86881 tagttaatga caattcatta gctgatgcac tttcagctac accatttgca aaggctaaag
    86941 gagcaccaat acttttgaca gaaagtgata agctagatga taggactgaa aaagagataa
    87001 aacgtctagg agctaaagat atttatttga taggaggtac tgctgtactt aataaagata
    87061 tagagaacaa gttaaaaagt aatggactta atgtagaaag aattaatggt aaggatagat
    87121 atgaaacttc actgattttg gctaataagc ttaaggatat aaaagatatt aaggaagttg
    87181 ctgtagtaaa tggtgaaaaa ggattgagtg atgctgttag cgttggggca ccagcagctc
    87241 aaaataagat gcctataatt ttgtctagtc ctaaggacgg agtagaagca tttgataaat
    87301 ttataaggga tgagaaagtt ataaaagcat atgtaattgg aggtacaaat tctgtttcaa
    87361 gagctgtaga aaagagtctt cctaatgcag aaagagtgag tgggaaagat agaaatgaga
    87421 ctaatgctaa ggtcatagaa aagttttaca ctgatacaaa tttaagtaat ttatatgtaa
    87481 ctaaggatgg tagtaaaaat gagaatcaac taatagactc gttagctgtt ggagtattgg
    87541 ctgcaaaaaa tgagtctcct gttgttttgg ttggtaataa attaaacaca aaacaaaggg
    87601 acatacttag tactaaaaaa ttaaatacta taacacaggt aggtggaaat ggaaatgaag
    87661 aagcttttga tgaaattaaa agtctacaag aaaaaactgt gtttgaagca aaaactgttg
    87721 aggaattaac tgatatgata aatatagcaa gtcctaatga tattataaac tttaaaccaa
    87781 aagagaatac tgtaaatgaa gcttttagaa tggtaacaaa taaaccaata actgtgaata
    87841 taaagggtga ttgttcaaag actcttacag tagatatgcc taatggtgaa gtgaataact
    87901 atgctacttt ggtaaatgtt atagttagaa atattggaga aggtggattt aataaccatg
    87961 atacaatcac tatattgtca gttcgtgaca aaaatggtag agttatagaa aatactagaa
    88021 attcagatat agatacgttg atgatattag cttctgctaa tgatacaaaa ttgattaatg
    88081 atggatatat aggaaaactt atagataatt catctaatag tgatataact aataatggta
    88141 ctatagataa aaaagttaat caggttgaag atttagaggc taaagtagat tcaattgaaa
    88201 aagctataga ttctataagt caaaaagtca ataaaataca agatatacta gataagcttg
    88261 gatttctaaa gaaatttctt agctaagaat atatatattt aagtgaagtg tttgttgtaa
    88321 ttgttctaaa gttatgtagt taaacaggtt tatatacaaa tagatttata gataaatatg
    88381 tagtttagta tatatttgaa taagctttgg ggaggtaaca tggggattgg aattgaatgt
    88441 aacaaaaaaa taaataaaag tattgacaaa actagaataa agaaaaataa tct
//
LOCUS       DAYAKB010000007        86125 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.007, whole genome shotgun sequence.
ACCESSION   DAYAKB010000007 DAYAKB010000000
VERSION     DAYAKB010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 86125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86125
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.007"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            83..1486
                     /locus_tag="ACGI3L_000599"
     CDS             83..1486
                     /locus_tag="ACGI3L_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9196329.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1577..1817
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1860..2558
                     /locus_tag="ACGI3L_000600"
     CDS             1860..2558
                     /locus_tag="ACGI3L_000600"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFG9196330.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2581..3582
                     /gene="trpS"
                     /locus_tag="ACGI3L_000601"
     CDS             2581..3582
                     /gene="trpS"
                     /locus_tag="ACGI3L_000601"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFG9196331.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4234..5801)
                     /locus_tag="ACGI3L_000602"
                     /pseudo
     CDS             complement(4234..5801)
                     /locus_tag="ACGI3L_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(5794..6319)
                     /locus_tag="ACGI3L_000603"
                     /pseudo
     CDS             complement(5794..6319)
                     /locus_tag="ACGI3L_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ia"
     gene            complement(6708..7454)
                     /gene="cdtR"
                     /locus_tag="ACGI3L_000604"
     CDS             complement(6708..7454)
                     /gene="cdtR"
                     /locus_tag="ACGI3L_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HFG9196332.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
     gene            8320..9522
                     /locus_tag="ACGI3L_000605"
     CDS             8320..9522
                     /locus_tag="ACGI3L_000605"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9196333.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            9527..10105
                     /locus_tag="ACGI3L_000606"
     CDS             9527..10105
                     /locus_tag="ACGI3L_000606"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196334.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGI"
     gene            10118..10297
                     /locus_tag="ACGI3L_000607"
                     /pseudo
     CDS             10118..10297
                     /locus_tag="ACGI3L_000607"
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
     gene            10443..11864
                     /locus_tag="ACGI3L_000608"
     CDS             10443..11864
                     /locus_tag="ACGI3L_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HFG9196335.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            12130..12612
                     /locus_tag="ACGI3L_000609"
     CDS             12130..12612
                     /locus_tag="ACGI3L_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HFG9196336.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            12667..13446
                     /locus_tag="ACGI3L_000610"
     CDS             12667..13446
                     /locus_tag="ACGI3L_000610"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9196337.1"
                     /translation="MKKIICGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            13756..14202
                     /gene="lspA"
                     /locus_tag="ACGI3L_000611"
     CDS             13756..14202
                     /gene="lspA"
                     /locus_tag="ACGI3L_000611"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFG9196338.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLVDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            14171..15118
                     /locus_tag="ACGI3L_000612"
     CDS             14171..15118
                     /locus_tag="ACGI3L_000612"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFG9196339.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            15478..16011
                     /gene="pyrR"
                     /locus_tag="ACGI3L_000613"
     CDS             15478..16011
                     /gene="pyrR"
                     /locus_tag="ACGI3L_000613"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFG9196340.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            16295..17506
                     /locus_tag="ACGI3L_000614"
     CDS             16295..17506
                     /locus_tag="ACGI3L_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFG9196341.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            17805..19457
                     /gene="cplR"
                     /locus_tag="ACGI3L_000615"
     CDS             17805..19457
                     /gene="cplR"
                     /locus_tag="ACGI3L_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Contributes to intrinsic pleuromutilin, lincosamide
                     and streptogramin A resistance; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein CplR"
                     /protein_id="HFG9196342.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(19672..21447)
                     /locus_tag="ACGI3L_000616"
     CDS             complement(19672..21447)
                     /locus_tag="ACGI3L_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT RNA binding domain-containing protein"
                     /protein_id="HFG9196343.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            21743..22777
                     /gene="ltaE"
                     /locus_tag="ACGI3L_000617"
     CDS             21743..22777
                     /gene="ltaE"
                     /locus_tag="ACGI3L_000617"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HFG9196344.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            23064..23894
                     /gene="dapF"
                     /locus_tag="ACGI3L_000618"
     CDS             23064..23894
                     /gene="dapF"
                     /locus_tag="ACGI3L_000618"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFG9196345.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            23898..24779
                     /locus_tag="ACGI3L_000619"
     CDS             23898..24779
                     /locus_tag="ACGI3L_000619"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFG9196346.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            24809..25426
                     /gene="gmk"
                     /locus_tag="ACGI3L_000620"
     CDS             24809..25426
                     /gene="gmk"
                     /locus_tag="ACGI3L_000620"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFG9196347.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            25429..25695
                     /gene="rpoZ"
                     /locus_tag="ACGI3L_000621"
     CDS             25429..25695
                     /gene="rpoZ"
                     /locus_tag="ACGI3L_000621"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFG9196348.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            25700..26899
                     /gene="coaBC"
                     /locus_tag="ACGI3L_000622"
     CDS             25700..26899
                     /gene="coaBC"
                     /locus_tag="ACGI3L_000622"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HFG9196349.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            27174..29663
                     /gene="priA"
                     /locus_tag="ACGI3L_000623"
     CDS             27174..29663
                     /gene="priA"
                     /locus_tag="ACGI3L_000623"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFG9196350.1"
                     /translation="MKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVIKIGHRILVPFGK
                     GNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWMKNRYLCTYIECI
                     NLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVEKVIDSKGKIKVD
                     KLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESDKIDDYIEQNKIN
                     VGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLEFKDYYREPKSIY
                     KSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVYMEIIEFALNQGL
                     DSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAVKAGKVRVLIGAR
                     SALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNITLILGSATPSIE
                     EYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSLKLQKEIRYAIEE
                     NNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRCHYCGYEKEIPKE
                     CPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGALDEILNKFKDKEA
                     DVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLITQVSGRAGRADKE
                     GKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNMLSVVVSGEDERLV
                     IKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQILFKDENIEINLLK
                     GIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            29681..30121
                     /gene="def"
                     /locus_tag="ACGI3L_000624"
     CDS             29681..30121
                     /gene="def"
                     /locus_tag="ACGI3L_000624"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFG9196351.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            30136..31065
                     /gene="fmt"
                     /locus_tag="ACGI3L_000625"
     CDS             30136..31065
                     /gene="fmt"
                     /locus_tag="ACGI3L_000625"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFG9196352.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            31075..31827
                     /locus_tag="ACGI3L_000626"
     CDS             31075..31827
                     /locus_tag="ACGI3L_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HFG9196353.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDIMDIEKAIGFLTGKNILVCN"
     gene            31896..32597
                     /locus_tag="ACGI3L_000627"
     CDS             31896..32597
                     /locus_tag="ACGI3L_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFG9196354.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            32659..33984
                     /gene="rsmB"
                     /locus_tag="ACGI3L_000628"
     CDS             32659..33984
                     /gene="rsmB"
                     /locus_tag="ACGI3L_000628"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFG9196355.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            33992..35023
                     /gene="rlmN"
                     /locus_tag="ACGI3L_000629"
     CDS             33992..35023
                     /gene="rlmN"
                     /locus_tag="ACGI3L_000629"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFG9196356.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            35043..35795
                     /locus_tag="ACGI3L_000630"
     CDS             35043..35795
                     /locus_tag="ACGI3L_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFG9196357.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            35812..37827
                     /gene="prkC"
                     /locus_tag="ACGI3L_000631"
     CDS             35812..37827
                     /gene="prkC"
                     /locus_tag="ACGI3L_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861606.1"
                     /note="PrkC, as found in Clostridium difficile, has a
                     kinase domain, two PASTA domains, and a C-terminal
                     Gly-rich repeat region; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing Ser/Thr kinase PrkC"
                     /protein_id="HFG9196358.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            37935..38672
                     /locus_tag="ACGI3L_000632"
     CDS             37935..38672
                     /locus_tag="ACGI3L_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFG9196359.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            38770..39654
                     /gene="rsgA"
                     /locus_tag="ACGI3L_000633"
     CDS             38770..39654
                     /gene="rsgA"
                     /locus_tag="ACGI3L_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFG9196360.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            39659..40330
                     /gene="rpe"
                     /locus_tag="ACGI3L_000634"
     CDS             39659..40330
                     /gene="rpe"
                     /locus_tag="ACGI3L_000634"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFG9196361.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            40339..40980
                     /locus_tag="ACGI3L_000635"
     CDS             40339..40980
                     /locus_tag="ACGI3L_000635"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFG9196362.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            41111..41740
                     /locus_tag="ACGI3L_000636"
     CDS             41111..41740
                     /locus_tag="ACGI3L_000636"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9196363.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            41795..42451
                     /locus_tag="ACGI3L_000637"
     CDS             41795..42451
                     /locus_tag="ACGI3L_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9196364.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            42865..43581
                     /locus_tag="ACGI3L_000638"
     CDS             42865..43581
                     /locus_tag="ACGI3L_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196365.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            43553..45889
                     /locus_tag="ACGI3L_000639"
     CDS             43553..45889
                     /locus_tag="ACGI3L_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9196366.1"
                     /translation="MLDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGG
                     AENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDT
                     YDGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVL
                     DTTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSY
                     GVNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYG
                     YGNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTL
                     SRIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNL
                     TYWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINL
                     KEKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQL
                     LDVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNV
                     SHDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSG
                     DVYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENL
                     IINISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTE
                     GSGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(46206..48884)
                     /gene="mngB"
                     /locus_tag="ACGI3L_000640"
     CDS             complement(46206..48884)
                     /gene="mngB"
                     /locus_tag="ACGI3L_000640"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HFG9196367.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDKYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIVKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(48959..50065)
                     /locus_tag="ACGI3L_000641"
     CDS             complement(48959..50065)
                     /locus_tag="ACGI3L_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFG9196368.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            complement(50179..50487)
                     /locus_tag="ACGI3L_000642"
     CDS             complement(50179..50487)
                     /locus_tag="ACGI3L_000642"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFG9196369.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            complement(50490..50942)
                     /locus_tag="ACGI3L_000643"
     CDS             complement(50490..50942)
                     /locus_tag="ACGI3L_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9196370.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            51176..53104
                     /locus_tag="ACGI3L_000644"
     CDS             51176..53104
                     /locus_tag="ACGI3L_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9196371.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSENSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            complement(53364..54125)
                     /locus_tag="ACGI3L_000645"
     CDS             complement(53364..54125)
                     /locus_tag="ACGI3L_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9196372.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLCYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            54344..54820
                     /locus_tag="ACGI3L_000646"
     CDS             54344..54820
                     /locus_tag="ACGI3L_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFG9196373.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKVLTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            54918..55070
                     /locus_tag="ACGI3L_000647"
     CDS             54918..55070
                     /locus_tag="ACGI3L_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HFG9196374.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(55230..55418)
                     /gene="rpmB"
                     /locus_tag="ACGI3L_000648"
     CDS             complement(55230..55418)
                     /gene="rpmB"
                     /locus_tag="ACGI3L_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFG9196375.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            55779..56129
                     /locus_tag="ACGI3L_000649"
     CDS             55779..56129
                     /locus_tag="ACGI3L_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFG9196376.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            56148..57791
                     /locus_tag="ACGI3L_000650"
     CDS             56148..57791
                     /locus_tag="ACGI3L_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFG9196377.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            57872..59929
                     /gene="recG"
                     /locus_tag="ACGI3L_000651"
     CDS             57872..59929
                     /gene="recG"
                     /locus_tag="ACGI3L_000651"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFG9196378.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            59988..60542
                     /gene="rsmD"
                     /locus_tag="ACGI3L_000652"
     CDS             59988..60542
                     /gene="rsmD"
                     /locus_tag="ACGI3L_000652"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFG9196379.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            60544..61041
                     /gene="coaD"
                     /locus_tag="ACGI3L_000653"
     CDS             60544..61041
                     /gene="coaD"
                     /locus_tag="ACGI3L_000653"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFG9196380.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            61045..61569
                     /locus_tag="ACGI3L_000654"
     CDS             61045..61569
                     /locus_tag="ACGI3L_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196381.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            61913..63832
                     /locus_tag="ACGI3L_000655"
     CDS             61913..63832
                     /locus_tag="ACGI3L_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9196382.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENIL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            63845..64132
                     /locus_tag="ACGI3L_000656"
     CDS             63845..64132
                     /locus_tag="ACGI3L_000656"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196383.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            64265..65524
                     /locus_tag="ACGI3L_000657"
     CDS             64265..65524
                     /locus_tag="ACGI3L_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFG9196384.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLMGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            65527..66267
                     /locus_tag="ACGI3L_000658"
     CDS             65527..66267
                     /locus_tag="ACGI3L_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9196385.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            66590..67900
                     /locus_tag="ACGI3L_000659"
     CDS             66590..67900
                     /locus_tag="ACGI3L_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFG9196386.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLISS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            67998..68915
                     /locus_tag="ACGI3L_000660"
     CDS             67998..68915
                     /locus_tag="ACGI3L_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9196387.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            68931..69740
                     /locus_tag="ACGI3L_000661"
     CDS             68931..69740
                     /locus_tag="ACGI3L_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9196388.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            69798..71546
                     /locus_tag="ACGI3L_000662"
     CDS             69798..71546
                     /locus_tag="ACGI3L_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HFG9196389.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKVREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     RYDKVKKYVLELLDRV"
     gene            71850..72830
                     /locus_tag="ACGI3L_000663"
     CDS             71850..72830
                     /locus_tag="ACGI3L_000663"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HFG9196390.1"
                     /translation="MFFLSISFIGFYLVIRDNSDTVKMQRGINIGNALESPKDFPWDV
                     KMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKIDKYVDYALDKDLIV
                     VLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELLNEPKENLSSQLLNE
                     YIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVVSFHYYEPNDFAFQG
                     NIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIFLGEFGITKEAPEVS
                     RRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILSALIEKR"
     gene            72835..75141
                     /locus_tag="ACGI3L_000664"
     CDS             72835..75141
                     /locus_tag="ACGI3L_000664"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196391.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTTS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            75152..76228
                     /locus_tag="ACGI3L_000665"
     CDS             75152..76228
                     /locus_tag="ACGI3L_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196392.1"
                     /translation="MKTLKVFFCSTKYLILVFIFFINTTFISSATSDKILDLSFKKIE
                     TDLNSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNFYIEIQNKNKSSQR
                     INLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEFEGKIYVNFNSLIN
                     EESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKLRFLNNIKIIGDEE
                     VQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTLSNKAKPGQIILQV
                     NVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMKKINFMNNIITFVR
                     ILFVSLVIICFGIYLYWKKCSKTK"
     gene            76246..77664
                     /locus_tag="ACGI3L_000666"
     CDS             76246..77664
                     /locus_tag="ACGI3L_000666"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HFG9196393.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            77679..78887
                     /locus_tag="ACGI3L_000667"
     CDS             77679..78887
                     /locus_tag="ACGI3L_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196394.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(78961..80349)
                     /locus_tag="ACGI3L_000668"
     CDS             complement(78961..80349)
                     /locus_tag="ACGI3L_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HFG9196395.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IGFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            80690..82024
                     /locus_tag="ACGI3L_000669"
     CDS             80690..82024
                     /locus_tag="ACGI3L_000669"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HFG9196396.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREISYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(82166..83083)
                     /locus_tag="ACGI3L_000670"
     CDS             complement(82166..83083)
                     /locus_tag="ACGI3L_000670"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFG9196397.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            83291..84175
                     /locus_tag="ACGI3L_000671"
     CDS             83291..84175
                     /locus_tag="ACGI3L_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HFG9196398.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            84388..>86125
                     /locus_tag="ACGI3L_000672"
     CDS             84388..>86125
                     /locus_tag="ACGI3L_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HFG9196399.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVED
                     IKIENKSARLIGKEEALKYKLDSVVSKKVDKIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTG"
BASE COUNT        33310 a         9325 c        14752 g        28738 t
ORIGIN      
        1 tcagtttaat aataatgaat ctattttatt aattttgaaa ttaaatttaa aataattaat
       61 agagagggga aattaaatta ggatggaaaa gaaaaaaata ggcctatgga gtttggtatt
      121 tatgaatgta tcagctttat atggtataag atggatagct aaatctacag catcaagctt
      181 tggtttagga ttaggtgcaa tacctatgtg gttattattc tcatttatat actttgtacc
      241 aggagcttta atttgtgctg aattagcttc tacatatcaa aaaggtgatg gaggtcttta
      301 cgattgggtt aaggaagcct ttggagaaaa gtatggattt ttagtttctt ggttaaactg
      361 gacagctaaa atattttggt attcttcatt tttaactttc ttagcagtaa atgtttctta
      421 tacaatagga aatccagccc ttgctgataa taagatgttt gtacttatat tatctttaat
      481 aatattctgg gcattatctc ttatagcaac taaaggaata agttttacaa aaatatttac
      541 taatacaggt gcattaggtt caacaatacc aagtgctata cttataatat tttcatttgt
      601 agcagtattt gtgttgaaaa aacatgatat agcttctaca tacacaatag cttcaatgac
      661 tccaaaactt aatatggatg catttgttgc tatatcagct ataatgtttg gtttagcagg
      721 agcagagact gctgctaact tcataacaga aatagataag cctgaaaaga acttccctaa
      781 ggcaatatta atatcagctg gaatagtagc ttcattatat gtattaggtt caattgcaat
      841 aacaatgata ataccaccag accaaattac tgcttctaaa ggtgtattag atgcactttc
      901 tgctgtttgt gcgtctttag gaattggttc ttggttggtt caattaatag cttttggtat
      961 agctttttca gtattaggag caatagttct ttacatagca tcaccaataa aaatgttatt
     1021 tggtagtgtt aaaaaaggaa tatttccaga tagtttagta gaggtaaatg aacacaagat
     1081 accttctaaa gcagttatac ttcaagcaat aatagttact ataatactat tggtgactac
     1141 attaatgcct tctgttgatg ctatatacaa tgttcttgta actatgacag cattaactgc
     1201 attattccca tatgtattgt tatatgcttc ttatattaaa ctaagaaaag agagaccaga
     1261 tgaaattaga ccttatacta tggcaaaatc aacaagtact tgcctaggtt tagcaaaaat
     1321 ggttttagtt gtaactgtag tgggtatatt attatctgca gcaccagtta tgcctacatt
     1381 tgctgaaaat gttatatatg agatagagat gattggtgga ggtcttctag ttatattatc
     1441 tggtctatgg ttatggaata gatatgaaaa gaaaacagct aaataaaatg tattttaaaa
     1501 atttcttttg gatattataa tatatagttg acaatttata gtgtaaggaa tattataaaa
     1561 taaagaaatt aataaattaa atcctgagat aagaaatagt aaataaatat atttttgcac
     1621 agagaattaa ggatgctgag aacttaataa aaagtattta ttgaatgggt ctttgaggag
     1681 taaaatgaaa tgtaatttaa tattacagag tatttgatat cgtgtatgca cgttatagca
     1741 tatattaaga tatatatatt caattttgag tgtatataaa tttaggtggt accacggaaa
     1801 atatatccgt cctattgatt taggacggat tttttaatat agaaaattta ggaggaaaaa
     1861 tgaacgtaat aggaattata ggtgcaatgg atgaagaagt tagtatttta gttgatttaa
     1921 tggatattag agagactata aaaaaagcta gcttagaatt ttataaggga attttggaag
     1981 gtaagaatgt agtgttagta aagtgtggca taggtaaggt taactctgct ctttgtgccc
     2041 agatactaat aagcgaattt aaggttgatg ctattgttaa tacaggtgtt gcaggagctt
     2101 taaacgaaaa acttgatgtt aatgatatag taatatcaac tgatgctata cagtatgatg
     2161 tagacactac agcatttgga gaccctaagg gagttatacc aagaatgaag acttctgtat
     2221 ttaaagcaga tgaaagactt atagatgctg cttacaaatc ttctgtggaa gaagtaaaga
     2281 ctcataaagt attaaaagga agagtagtta caggagataa atttataaat tctaaagaat
     2341 taaaagaaga attagtaaat gattttggtg gatattgtgg agaaatggaa ggtggagcta
     2401 tagctcatgt atgctattta aataatactc catttgtaat aataagagca atgtctgata
     2461 aggcagatgg aagtgctgat gttacttatg atgtatttgt acatgatgct gccaataact
     2521 ctaaagacat agttttaaat atgttaaaat caatataaat atataaggag gtacaaaaaa
     2581 atgagtgaaa aaaaagttat atttagtggt gcacagccat caggcaaaat gactttagga
     2641 aattatttag gagctataaa aaactggact gaacttcaag acaattatga ttgttattat
     2701 agtatagttg atttgcatgc aataacagta cctcaagacc ctaaagtttt aagagccaat
     2761 actatagaat tacttgctca atatatagct tgtggattag acccagaaaa aaatactata
     2821 tttatacaat cacatgtcaa agagcatgtt gaacttatgt gggtattgaa tactatgact
     2881 tatatgggtg aattaagtag aatgactcaa ttcaaagata aatcacaaaa gagtgaagca
     2941 aatctaaatg caggtttatt cacatatcca gttcttatgg ctgctgacat attgttgtat
     3001 caaactgacc tagttccagt tggagatgac caaaaacaac atttagaatt agctcgtgat
     3061 ttagcaaata gatttaataa tagattttca cctacttttg tagttccaga aggatactac
     3121 ccaaaaggtg gagcaagagt gatgagtttg caagagccaa ctaaaaaaat gagtaaatcc
     3181 gattcaaatg aaaatgcatt tatactatta gcagatgatt cagattctat aaagagaaag
     3241 ataaaaagaa gtgttactga ttctttaggt gttgtaaaat acaatgatga acaaccaggt
     3301 attaaaaatc taattgatat atattctaat ttaagtaaaa agagtgtaga agagattgta
     3361 aacatgtatg aaggaaaggg ttatggcata tttaaagaag atgtggctga agtagtatca
     3421 gaagctttaa gacctataag agaaaaatat gttgaccttc ttaataataa agattattta
     3481 gaaaaaatat atagtatggg agcagaaaaa gccgaaaaac aagctagaaa aactcttaga
     3541 aaagtttata aaaaagttgg atttatagag agaagatact aattattagc tatctttact
     3601 tgataaataa attttaaagt tattaaaaag gtatatgata tgaaagagag agtctcaaag
     3661 tgaacttttg ttcatgaggc actctttttt gtatgaaata aaatatattt taatcatttc
     3721 aacaatgaaa aagaggatta tctctatttt gagacagcat cttttgataa taaaaaaaga
     3781 tgagcttttg ctcatctcaa aggggttaga ttattcttac tttggggaaa gtagaataaa
     3841 ggtaaaagtt aactgatgtc aactttgtct tttttgcata tcactactga gcataaaaaa
     3901 atcagaaaac catagccttc tgaaacaact tctaacatac attgtatttt atacccaata
     3961 tgtaatttat gagttaattt taactcttat aatgaaaatt gtcaataata tatcaaaaaa
     4021 atatttttta aatttatata attaaatgaa tttatgttta tatataggtg atatgataca
     4081 gataattatc tttttaatac aatatagttc taaaaaagaa tatattagaa gaagataata
     4141 tttaaataaa aaatacctta taaagttaat tttttaatac tttataaggt aaatacatat
     4201 tgtattgtgg ggataaattt aaatcatttg atactaatca acactaagaa ccaataactc
     4261 tctatcatct tgagtaattg tatatattct taatttcttg tatgtcataa tattttctcc
     4321 acctgtaaaa taactcctaa gattaacaca atcagtttta ggttgatttg tatctcctaa
     4381 ataattacgc aattctttat ctttagtttc aatatcttta aatccaaaat attgtaaagt
     4441 agcttcaact ctatattttt ggacataatc gagagcttct ttattagttt atgttggtgt
     4501 aaaatacata ccatttatat aagcctttat tgtacttgga ttaaatttaa aatctgcaga
     4561 atatatttta tgtgtaacta ttatttcttg aacagttgga attttaactt ctggttcatc
     4621 aagtatttca ggagtactat ttagctctgt aatagataag ttatctaagt atattgtatc
     4681 actatcaatt aatgctatat ttatattaga agaatctttt tcagtagttt caaattcata
     4741 actaaatttt gtatatcctt gttctagtac caaataatcc gttttttctt cttttacttt
     4801 tatatttaca attattgaat tatatgttaa aggatttttt gaattttact aaaaacataa
     4861 cgtttataag gttttagttc agacataggt attttaatct tcgtctcacc atttaatcta
     4921 tttgctgagc cttttaaacc atcttgattt gtagtattaa cattactcca tatactaggg
     4981 taattattgt aatcatcaaa attagtaaag taagttggtg tttttataag tatattcatt
     5041 cctctttcaa gtttaacatt acatatttgt ttatcagaca aagtttttaa actgtcttta
     5101 atcttattgc ctatattatc atcaaatatg agttcaacac aactttcatc tattggtata
     5161 ttattaaaat ataacaaacc atctttttta gtagtgccaa aagttttttc aattgcttct
     5221 ccaattgtaa gttcaggtgt tttatcttct gggacctgta aacttttagc agtaattctt
     5281 cttttgtaag attcattttc tgtatctaat ataatagata cagaaatact gtcaatttga
     5341 cctatatcgt cttaccaact atttcattct gttactattt gtccagaacc attttttgta
     5401 ccaaaatttc cacttacttg tgttgtttct aatttaattt gctttccatc atctaatttt
     5461 tttaattaat tataatttat aggaatcagt ctagaactaa attgatacat tgtgttaaga
     5521 gccataggtg aaaatccttt tttgagataa gtatttccag gagatagatt attgccaatt
     5581 tgattttctt gtgctttgat agttgataat gcatctccat ctaacactaa atttgttgtt
     5641 ggtgtcactt tgtacatagg tgcagtacct gtgttgtagt atctaatatt tgcatttata
     5701 tatgcagatt ctcctttgtt tatacttaat ccagtatttc atgattatcc attgctattt
     5761 tgaacagcag ttgaattatc tgttgtatgg taataatttg tcttgtatag tttctttaaa
     5821 ctcattaaat ttttctaatg aaatttcgtt ttgatttttt gttcttatta ctttattaaa
     5881 tgcaaatttt tctggagatt caaaataata tacatacata ggtttatcta ttttattttt
     5941 tgatatagca tttcgaagtt ctctatattc tttttctcaa gaatttgctt ctatttgata
     6001 atcataaaaa taatttcttg tctgagaata tttgcttatc tctatagaat cttttttata
     6061 tgatcctaat acttcttttt cagatttttc aagtttttga tcttttcttt ctcattcttt
     6121 agccttttct ttatctttaa aaaaatcctt ctgatctttc tataggagcc ttgtaagtag
     6181 tattacaaac ttttccacta tagctttgta aatcttgtgc ataaatgtta ttaggtaaca
     6241 aactacctaa agttagatat aatatcaaca atatagatat acaattacta atacttttat
     6301 gtttcctaaa ttttttcatt tattctccct acaaatatta gtttagttaa cttttgaatt
     6361 ttaatttatt tagattatat aatctaaata agaatttttt atataaattt cataaaatat
     6421 gtaggtatat atcataaaaa tatgtattta tatgatatgt cagtacaaaa taacaactga
     6481 atattttaaa gagactattt cgtactttta tgatttaatg agctatctta tcgaatcata
     6541 atctaggaac aattgttata atatctaata gtagttatat atgatatagt cagtatgtgt
     6601 tttttcacaa tatgattatt atatagagga ttcttaggga ttactctttt tgtataaaaa
     6661 agagatggtt caaattttta tcttgagaca tctccttttt ctatttatta tgttttaata
     6721 atattcttta aaatatttct atatgtatta gatatacgac atatatggcc attactcatt
     6781 ttaatattat ttttctttag gtcgagagaa acaatatgat atttattaac tacaaaagat
     6841 ttatgtacac ggataaagca tgcatctaaa tctggtaaag actttaaact tttatagaat
     6901 tcaaatattc tagaagtagt cactaatttt attttatgtg gaatagtgct tgtttcaaaa
     6961 tatataactt catcaaatga aattttccat agtgagaaat ctgaatagat agtaaaaaaa
     7021 ttagagcgat aatttttttc tttaatgtat cttttgtgag caattttaat acaagctttt
     7081 attttacttt cagcaatttc catatcatgt tttagtataa agtccataac ttctaaccta
     7141 taatcgaaga tccctaaaat catttctata tgatttgtaa gaaatatgat tggactaata
     7201 taatctgatt ctctaatttt ttgtgctatc cataatccat cacataattc attacttatc
     7261 ttatattttg cgtctacaac tataaaatat attcttactt tatttttttc agtaagctct
     7321 tttaataaca aatttgcatt atgatataat cttacaacat cattatcaaa accttctttt
     7381 attaaaatat tatttatttt ttcttttagt ttcattccaa aacaaacatc attatcaaag
     7441 attaatatat ccactaaata ccctcctata aaaaattcaa aagtaaaaaa acaaaagtat
     7501 tttatagaaa atacataaaa taacactagg agataaataa gattaaggat agttagaatt
     7561 aaggtatatt tatgcttgtt tatatagtat atcttatact tatagtttac aataataaag
     7621 taaattaaat caatatatta ttataaaaaa tttatttata ttaaataata tgttttatat
     7681 taacttagat aataaaaatt ttctggaatt tttattctta tacgtgataa aaatagttat
     7741 aactatgtat ttcagaaaat aaaatttata ggtatttttt ttagaagaat tatttaacaa
     7801 taattataga agtaactttc aaggttgaca aattattatg gtaaatatac attataataa
     7861 tttattgtca aacatattat tttaaatatg ggatttattt actttatcga tatacggcta
     7921 tataataaat atataacaga gagatgataa tgtgtgttta acacaattaa atcaaatgag
     7981 atatttgaac aaagaatagt ataaaatttt taaagaaata tgttgtatga gtaagaatct
     8041 acataatatt gtattatatg atattcgaaa gtattatttc taagaaaaga gatttctaaa
     8101 gtataaaatt aaatactaga attgtaaagt taataataac tacaagttat tacaagctta
     8161 tgctagctag tattagttgt taatagaagt acaactattt cttatttaat taaaagatta
     8221 aatgtggaaa gttttgtgat aggattactt caaatatgta atttataaca accataataa
     8281 atttagagtg tgtaaaaatt tattttttaa agggggatta tgaaaacatc aattttaatc
     8341 gcattaatag aaaagacaag ccttattgta gtattgtttc ttctaataac aaagttaaaa
     8401 atatttaagc agatatttca aaaggaagaa tatagtttta atgacttggt ctgtatagca
     8461 ttagttttta cttttttagc catatttgga acttatagtg gtataaatta tatggggtca
     8521 atagtaaaca ctagaataat atctatagta tcaggtggca ttttatttgg tccgatggta
     8581 ggtattacag caggagtttt ttcagggatt catagatatt ttatggatat tggggggata
     8641 acatctgttc catgtctttt atcaagtata ctagcaggtg tattatcagg atttctatat
     8701 aagaggatac caaaacaaca tagagtaatg tatggaatat tggtaggcat gatttctgaa
     8761 agttttacta tattacttat atacttaata tcatatccac attctttagc aattcaaata
     8821 atcggtggaa tatatttacc tttaatagtt gggcagattg gaataggatt tgttatatct
     8881 atagtagagg ggattgagaa agataaaaaa gatatagaag cgagaaataa agcagaaata
     8941 aaagcacttc aaagacaaat taatccacat tttttgttta attccctaaa cacaatagct
     9001 tcatttataa gatttagtcc agataaggct agagagttaa taataaattt atcaacttat
     9061 ctaagatata atcttgaata tagtgataac ttaattgata taaataaaga gattgaacaa
     9121 gttaaatctt ttgtagagat agaaaaagct aggtttggag aattactaac tgtatcttat
     9181 gatatagaag atgtaaatat aaagattcca agtttgatta tacaaccatt agtggaaaat
     9241 gcaataatac atggtatttt agaaagtggt agagctggtg tagtgaaaat atccataaaa
     9301 aagttaccgt attcattaga aaatactgtg agaatatcaa tagaggataa tggtataggt
     9361 ataagtgagg aaattataaa taatgtatat caagataata tgccagaaaa taagattggg
     9421 ctttataatg tacatttaag gcttaaactg atgtatggaa gagggcttaa tataagaaga
     9481 atagataatg ggactttgat agtattttat gtaaaggagt agaagtatga gagctataat
     9541 agtggaagat gaatttccag caagaaagga attgagatat tttattgaaa ataaaagtgg
     9601 aatcgaggta gtaagtgaat ttaccaatgg tatagaggtg ttagacttta ttcaggaaaa
     9661 taaaatagat gtaatttttt tagatataaa tatacctcat cttgatggaa tgctacttgc
     9721 aaaaacatta aatcagttta aatcaagacc taaaattgtt tttataacag catatgaaag
     9781 ttatgcagta gatgcttttt ctttggatgt atttgattat atattgaaac catattctga
     9841 agagagaatt atttctatgc tgaataaatt agaaaaaagt gagatgagtg atattgaact
     9901 atttaatgta aatagtaatt tatacaaata taagaaggaa gcagtaaatc aggagataga
     9961 agaaataaca cataaaatta gcctttggaa aggtgataaa ttagttgtaa tagatattga
    10021 tgatatatat tactgtgaag ctaatgaaag gcagacattt atatatactg agaaagaaaa
    10081 gtttatatta aaagaaggca tataagaagt cgaaaatctt ataaatgata aaacattttt
    10141 tagaacacat aggtcttata tcgtaaactt aaccaaagta aaagaaatta taccatggtt
    10201 taataataca tacatattaa aattaaaaaa tagtgattat gaagtaactg taagtagaag
    10261 caaagtaaaa gaatttaggc tgttaatgca tatataaagt catttcatgt acttaaatat
    10321 gcacttaatg taattaatat ttatattagc ataaaaaagt attactattt gaactggaaa
    10381 tagttttctt aaactcataa aaatttataa agcaattata taaaaactaa ggggatgaat
    10441 ttatggtaag ctttttaggt tcaatagtag tacttatagt aggttatttt gtctatggta
    10501 cttttgtaga aaaggttttt ggaaccaatg acaaaaatca aactccagct atagcttgta
    10561 gggatggagt agattatgtg ccaatgaaat ggaagagaat ctttttaatt cagtttctaa
    10621 atatagcagg gttaggtccg atatttggag ctatacaagg agcattattt ggaccatcag
    10681 catttttatg gattgtgttt ggaacaatct ttgctggtgg agtacacgat tttgcttcag
    10741 gatatctatc aatgaaaaac aaaggtacat ctgcatcaga gttggtaggc ctttatctag
    10801 gaaatggtgc aaaaatagca atgagaatat ttagtgttat tcttttagta ttggttggag
    10861 ttgtatttgt aacaggtcca gcaggattat taaagacatt gacaggtgta aacgcacaaa
    10921 tatgggttgg agtgataata ctttattata ttatggctac tgttttacca atagataaat
    10981 tgattggtaa aatatatcct ttatttggag cagcattatt aattatggca gtaggtgtag
    11041 ctggaggatt aataataaag gggtataaca taccaaatat aaatttacaa aatatgaatc
    11101 caaatggaac acctttattc ccatacttat ttataacaat agcatgtgga gcaatatcag
    11161 gttttcatgc aactcaatca ccacttatgg cgagatgtgt tgagaaagag agtgaggcaa
    11221 gaccagtatt ttatgggtca atggttgcag aaggtataat agctttagtt tgggcagcag
    11281 cagccatgtc atatttccat ggcatacctc aacttaatgt gatatttaat gatggtggag
    11341 cagcaacagt agtaaataca gtatctgttg gattaatggg gcctattgga ggagctttag
    11401 ctatacttgg agttgtggca tgtcctataa cttctggaga tacagcattt agaagtgcta
    11461 ggctgacaat agcagatgca atgaattata atcaagatgc agtcaaaaat agatttttaa
    11521 tagctttacc attattcgca gttggtgttg ctcttacatt tatagatttt aatataattt
    11581 ggagatattt ctcttgggca aatcaaacac ttgcaatgat aatgttgtgg actggttctg
    11641 catatttagt caaagcaaat aaaaaccatt atataactac attaccagca ctttttatga
    11701 ctgtagtaac atttagttat ataatgcaag caaaagaagg atttagacta ccagttaata
    11761 tatctaatgg aataggtgtt attgtagcaa taattcttgg tcttttattc tttaaaaaag
    11821 caaaacatat taaagaacaa aataatcata aattggcaag ttagtaaaat aataactata
    11881 aaaattaaaa aattgtattt aaattatgtt caaagaagag actatctcaa aatagagata
    11941 agtctctttt ttattgctga aaggataaaa atatatttga tttcatataa aaaagagggt
    12001 taaatgaact aaaaatttca ttttgagaca ttccattttt cgaatcaaat cttattttta
    12061 ttgtatgttt aatttacttt tccacatact atttttatga tgtaaatatt aaaattagag
    12121 gtgttaaaaa tggatactaa aaaatataaa gataaattat tgaaagaaag agaaaattta
    12181 actaatttag tagaggatat gaaagataat actttatttg gagatacaac taaacataca
    12241 agtgaaaagt attcatcagg agaattatct agttatgata atcatatagg agacatggga
    12301 acagatttat atatgcaaaa tatgcaaaac agtctaataa atcatgaaga gggaagattg
    12361 tatcaaatag acttagcatt atctaaaata gagaatggaa catatgggat ttgtgattta
    12421 tgtcataatc aaatagattt agaaagattg gatatattgc cagatacaag tttatgtaat
    12481 gattgtgcaa agaaggaaaa taatttatta ggtgatgcaa tgcaaaaccc tgatgtagaa
    12541 gattctaact tttattcaga agacctaaca aatttaactg atttaaataa aaatggaata
    12601 ttgagagatt aaaaaactga cattataaaa tatattgcta gaatgaatta gaaaagaggt
    12661 aatgacatga agaaaataat atgtggtata tgtatatgtt tattatctat agtaggtgta
    12721 tatacatata atcataatac acataatcaa gatagttcaa aagaagcata tagtttaaat
    12781 gacaatataa aagacgatta tgaagatgta ataataaaaa aaggaaatga ggatgaaaaa
    12841 attttagcat tgacttttga tgatggtcca gatgaggatt ttacaccaca agtacttgat
    12901 atattaaaga aaaatgatgt aaaagcaact ttttttgtag ttggagaaaa agtagaatat
    12961 aacaaagaat tattaaaaag acaatatgat gaggggcatg aaatagggaa tcatacattt
    13021 acacatataa atgttgcaaa aaatagttat agtagtgttg aaaaagaaat aacagatacg
    13081 caaaatatta taaaaagtgt gataggagta gaaccaaaga tatttagacc tccatataga
    13141 gccatgagta aaagtgtctg tgatattata gtttctaaag gaatgaatat aattctttgg
    13201 tcaaacttag accctagaga ttggtctaac cctggagtag atgcaattat aaatactatc
    13261 cttacaaagg tccaaaatgg taatataata cttttacatg attataacac taaaagaaat
    13321 gataaatcac aaactataca agctttagaa gtagtaattc ctaaattaaa agagagagga
    13381 tataaattcg taacagtatc tgaacttata caacatttag ataaaaataa gcaagtgcaa
    13441 aagtaaaaat atttgtttga agattagtgg tgattgtaag tttaaattac agacatcatt
    13501 aatctttaat ctataaaata cacaaaaaat attgattagt atggtatttt taaatttttt
    13561 atacataatg atatgatttt aaatatgtag aaatctacaa tataaaaaaa gtagtactat
    13621 tttaaatttt gttctagctt tattaagaaa atacaatttt aataaagttg ctctttagag
    13681 catttttttt gtataataat aatagtgtgc ttcaaataaa attggttttt aaataattta
    13741 tagggggaaa aatcattgct atatatatta ataataattc tactcatagg tttagaccaa
    13801 ctgtctaaaa tatgggtatt gaataatttg gtggatgtat caacaatacc aataataaat
    13861 aatgtatttc atttaactta tgtcgaaaat agaggtgcag catttggatt attacaaaat
    13921 aatcaatgga tatttataat tgttgcatta cttgcaacgg tatttggatt atactatctt
    13981 aatacaagga aagtacatat atttggaagg ttgggaatta tattaattat atctggtgca
    14041 ttgggaaatc tagttgatag agtacgatta ggttttgtgg tagattactt cgactttaga
    14101 gttatatggg aatatgtatt caatgtagct gatgtatttg tagttgtagg aactgtgttt
    14161 ttatgtatat atgttttatt ttttgaaagt aaaagtaggt gatataatgg atgaagtaaa
    14221 agagttttta gtacttgaag aggaagaaga agttagactt gatatttatc tagcagaaca
    14281 attaggtgat atgtcaagaa gttatataca aaaaattata aaagatggaa aagtaaaggt
    14341 taataataaa gtagaaaaag ctagatatct ggttaaagag gaagataata ttgttataga
    14401 gataccagaa cctaaagtat tagaagtttt acctcaagat attccaatag atattgtata
    14461 tgaagatgat gatgtcttaa taataaataa acctcaggat atggttgtcc atcctgctcc
    14521 tggaaactat gaaaatacgt tagtaaatgg gattttatat cattgtaaag ataagttgtc
    14581 atcaataaat ggagttatta gacctggtat agttcataga atagacaaag atacttctgg
    14641 tcttcttatg atagctaaga acaattatgc acataatttt ctagcagaac agttaaagga
    14701 acatactata actagggagt atgaatttat atgctatggt gtggttaaag aagataaaat
    14761 aactgttgat aaacctatag ggagaaatcc taaggataga ttaaaaatgg ctgtagtaaa
    14821 agatggaaaa aatgcaatca ctcactttga agttgtagaa agatttgata agtttacaca
    14881 tatgagagct aggcttgaaa ctggtagaac tcatcaaata agagttcatg ctttgtctat
    14941 aaatcaccca cttttaggtg attatgtata tggtccaaaa gaaactaaat ttaaattaaa
    15001 aggacaaact ttgcacgcta agaagttggg atttatacat cctactacta aggaatatat
    15061 cgaatttaat tcagaattac ctgagtattt taaggaagtt attaaaaaga taaaataacc
    15121 atttgtataa tacttataaa tcattttttg tttttatata agtaaataaa tttagtgaaa
    15181 tttaaataaa atatcttata ttaaagtatt ttgtttaaaa aagcttgaaa aatttgaaat
    15241 ataaatatat aatttgagtt gatagattaa aaaattatct ttaaacgata cagagatatc
    15301 gtaagacaat tgctaaatta cactgtatat tttttatata agagcttctt gtcttgtgat
    15361 gagaagtttt tttgttgttt aaattgaaat tttaaataaa aataaattta taaaaaatta
    15421 aaagaaagga gtagatttgt caaatagata tattatatct ttgacaataa ttatgatatg
    15481 gtagaaaaag ctcaattaat ggatgaaaag gcaatagcaa gagcaattac tagaataagt
    15541 catgaaataa ttgaaagaaa taaaggtgta gaaaatctag ttttagttgg aataaagact
    15601 agaggtgtgc caattgcaaa tagaatttct aagaaaatag aacaaataga aggaacaaaa
    15661 gtagatacag gagatattga tataactttg tatagagatg atttggaaaa aattcatgtt
    15721 gaacctgtag ttaaaggaac ttatttagat tttaatgtaa atgataagac agtagtttta
    15781 gttgatgatg ttttatacac tggaagaact gtgagagctt cactagatgc tattatagat
    15841 ataggaagac ctaaatcaat acaattagca gtgctagtgg acagagggca tagagagttg
    15901 cctataagag cagattatgt aggaaaaaat gtacctactt ctagacatga aattatatct
    15961 gtcagtttat tagaaattga tggagaagat tcagttacaa tcaaagaata attattttta
    16021 agtattatat aaaagcttag cattgaatag tcagggagga ggataaagct tacatagatt
    16081 gcacaaaata aatattataa ttttatggat gtgagtctta atgtagtttt tattctcctt
    16141 tatttgagtt tttgatgtcg taaaatgtaa aataatgata aattatataa taagtatata
    16201 gaggttaaaa aatagaatct agggaatgat aattaattaa aaggtattaa ttaaacagag
    16261 gatttattta tatataataa ttttggaggt ttttatgaaa aaaacgataa tgtctttaca
    16321 acatctatta gccatgtttg gagcgacagt attagttccc attttgacag gttttaatcc
    16381 gtcagttgca attttctgtg ctggtgttgg tacattgata tttcattttt gtacagaagg
    16441 aaaagtacct gcctttttag gttcaagttt tgcgtttata ccagttatac tagcagctaa
    16501 agaggcgtat ggtggagatt tagcatatgc tcaaggtggt ataatagtag caggattaat
    16561 ttatattata atgtcgatta tagtaaaagt agttggtgta aataaaatta aattatattt
    16621 tcctgcacaa gttacaggag ctatgatagt agttatagga ttaaatttat tgccaacagc
    16681 ttttagtatg gcttcagcca attttgtgat agcatttata actttagcaa tagcaatttt
    16741 aaccaataag tttggtagag gatttataaa acaattagga atattaatag cagttttttc
    16801 tgggtatata atctgtttga tattaagatt agtagatata actactatta cagaagcaag
    16861 tttatttgca atacctaact ttacagttcc taagttcagt ttaggagcaa tagtgattat
    16921 atctccagtt gtattagctg tatttatgga acatatagga gatatgacta ctaatggtgc
    16981 tgtagtaggt aaaaacttta tagaaaatcc tggattaaat agaacattac ttggggatgg
    17041 atttgcgact atagttgcag ggtgtttagg aggaccagca aatacaactt atggagaaaa
    17101 tacagcagta cttgctataa ctaaaaacta tgacccttca atacttagac gtacagcaat
    17161 atttgctata ttgcttgcat gtgtaggcaa gtttggtgga tttcttcaaa gtataccagg
    17221 ttcagttatg ggtggaatta gtataatgct attttcgatg ataacttatg taggattaaa
    17281 aactataagg gacagttctt gtgtagaaag taaaataaat atattaatca tagcagttat
    17341 attattaata ggtcttggaa caacatattt atctaataaa ggtatttctg ttggaatccc
    17401 tataacaagt acagtaaaga taactggtct tagtttagct gcaattgttg gaattgtatt
    17461 aaacagaatt ttaaataatc aggactttaa agttgaagaa gaataaattt aaagaataag
    17521 ttgtatattg aataactaaa attagttaat tttctataga catttgtaat taatgttgat
    17581 ataatgatta aaaataaatg aaagaaaggg caaggtaact aggacaatga gaatataatc
    17641 tattttttat aatttaaagt attgtaattt ttgaaaagcc tattttggtg gctttatttg
    17701 caatgcttaa attaaggaga gtagattata gtctatacgt ttatttgtta tgcctattta
    17761 tagaatctct ccttatattt aagtgtgtta aggagggatt ttttatgttg ttagtaaaag
    17821 tagagaattt aaagaaatat tatgcagata aattaatttt ggatatagat aaacttgaaa
    17881 tattagaaaa tgacaaaata ggtctagttg gttcaaatgg tcaaggaaaa acaacattat
    17941 taaaagcaat attgggagaa atagaaattg atgaaggata tacttacctt acagaaagct
    18001 attcttatat aagtcagagt gaaaataata ttgaaacatg tagtcatagt aaggagaaga
    18061 gtcttttaaa tgctccagat aaatttgaag aacacttatc aggaggggaa aaggttaagt
    18121 taaaaatagc agatgcgctg agtaataaga aaaatatcat aatagctgat gagccaactt
    18181 caaacttaga taaaaaaagc attggggttt tggaagatat gtttaaaagg catgagggag
    18241 cattattatt aatatctcat gatagacgtt ttctggatga gttatgtaca actatattag
    18301 aactagaaga tggaaaacta aaagcttaca aaggcaatta cactgattat ttaatgcaaa
    18361 aagatgaaga agtaaaaaga gctgattttg agtatcaaga atatgttaaa gagaaaaaaa
    18421 ggcttgaaaa agctctttta tataaaaaag ctttaagtga tggcataaga aaaacaccaa
    18481 aaagaatggg taattcagaa gctaggttgc acaaaatggg tggtcagact aataagaaaa
    18541 agttggactc aaatgtgaag gctataaaaa gcagaattga taaacttgag gtaaagaata
    18601 aacctaaagt ttctaaagaa atgaacatta agattcaaga tggtatggag ataattagta
    18661 aaaatctagt agaggtaaaa gatatgactc taaagttaga aaataagctc ctgttagata
    18721 atgtttcctt taagataaaa agaggtaaaa agatagcatt attaggtgat aatgggtgtg
    18781 gaaaaagtac tctgataaaa gaaatattgg ctgataaaaa tgacaatata aaaataaata
    18841 acaaggtaaa agtaggttat tttgaccaaa atcaaagttt attagatgag gaaaagagtg
    18901 ttctatacaa tactaaagtt aatagttcat ttgatgaatc ttttataagg ataaacttaa
    18961 gcctatttgg gtttaaaggt gatgatgtct acaaaaaagt aaaagtactt agtggtggag
    19021 aaaaggtaaa aatagcacta tgtaaaataa tattggaaga taataatttt ttagtatttg
    19081 atgaaccaac aaattactta gatataaaat ctatggaagc actggaaaag gcactgataa
    19141 atactgataa aactatgctt atagtgtctc atgatagagt atttgtatca catatttgta
    19201 actatattat agagataaaa gatgctaaaa taagggagtt tgattgtaat tatgacgaat
    19261 atacaattag cagaaataaa aaaactccta gtagagaaaa ccaaatcaaa aaagaaaatc
    19321 ttctagtatt agaaaataga cttacaactg ttatatctat gttatctata gaaaaagata
    19381 atctaaaaaa agaattgtat gaatcagaat ataatgaatt actaaaacaa atcaataaat
    19441 taaaaaatag cttttagtgt taacttttta attacatcta tataagaaga ctgaaaatat
    19501 ttgttgggaa tataagtata gttattaaaa cagaaaagta ttttgttaga aaattaaaag
    19561 taagctaatt agaaagtggc cttattattg tactttataa gaaggccact atttttattt
    19621 agaatgataa tgtgtagttg tctaacattt attttgtatt tagtgcagaa tttattcaga
    19681 tttaacctta agcttggcta ctgtttcttc ttcaggagta acataaatag tactgttagt
    19741 ttcataaata accatacctg gtttagaacc actaggtttt ttcacatttt ttctcttagt
    19801 atagtctaca ggcacctgag aagaaagttt tgacttacta aagaatgctg ctagcatagc
    19861 tccttcaaat acagtattat cagggacttc cttaccagca cactttatta ttacatgaga
    19921 accaggaata ttctttgtat gcatccataa gtcatcatta tcagcaagtc ttagtgtaag
    19981 atagtcattt tgcttattgt ttttaccaac caatatttta aatccatcag aagaaacaaa
    20041 ttcatgaggt tttgtagatg ggatagtatc ctttttactg tttttctttt gagtcttgat
    20101 gtatccaacc ttagcaagtt cttcttttat atcttgtaat tcagctaaat tttcacagtt
    20161 ttcaatactt aaaattatgt tttctaagta atctatttct tccttattta aggaaatttg
    20221 atgagatatc tcgactttag catgtttcat tttgttatac tttttaaagt atttttgagc
    20281 attttcagat ggtgtcaagt ttttatttaa ttctattgtt acatcattac aattttcatc
    20341 atagaagtta gcaacttcaa tactttccat acctttttct accatataaa tatatgaagt
    20401 aatcaattct ccttttatct tataaatgtc tgcattttcg gattctgata attcttcttc
    20461 ttgtttttta agtttattat aaagtctatc aagcttaaca gatatactct tctttaaatc
    20521 agatgaacgt tgattaattc tatctttaat atccttagtt ctatagaaat cttccagaat
    20581 acgagacata ctatccttat ttatatatga taaatcgcta aataatgtaa ggtttataca
    20641 actgaaatca actaccttat ccaccttttt atctataata atgcaaggag agtatttgtt
    20701 agaatttata tcattgaata aattacaaaa tactttgtgt aaagaatcaa attgttcatc
    20761 agatatatcc tttatgatag cattttgatt tacacctgct ctgtagcaaa tttctttagc
    20821 tataataggg cttataccta gaaatttaga atatatagac ttaaagatag gtccttccaa
    20881 ttcctctagg tttttaataa acaaatcctt agatatatca tcaagagggt tgagtttgtt
    20941 ttgttctggt ggcaatgaat aatcatgacc aggtaaaact tgacgaactc tacttatgct
    21001 aaaagggact ctttttatag aatctataat tttattttct tcaccatgag ttattattat
    21061 gttgctatgt cttcccataa tttcaatcat aatattttta actgtctttt cttttaattc
    21121 atctaaagat tcaacactta tttttattat tctttcaaaa cctatttgag aaatttctac
    21181 tatatttcca ccttgtatgt attttctaag taacatacaa aacataggcg cttttagagg
    21241 gttttctttt tgataattac ttgtaagata aactctagga tttgaggcac ttgcacttaa
    21301 aaccaatcta aaattttctt tattatttct tatattaaaa attacctcat catcttcagg
    21361 ttgatgtatc ttatctattt ttccacctgt aagttttgat gataattcat cgactattga
    21421 atgtataact aatccatcta atgccattta tagcacccct ttctttgacc aaaatgagtc
    21481 agtaaattaa ttatacacat aatatacgct ttgtgactag ggggaattta aacaatagag
    21541 attaatattt aaattgtata attatttata tttattagag aggaaacttt atttttaaaa
    21601 ttaataattt aaagtagatt aaatataaag taaatatagt ataattattg tgtagagtat
    21661 aagctatgaa agtatatgaa ctttacagaa aaaatcaatt ttaaggttct atagtatata
    21721 aatatgaaag aaggttgaaa aaatgagatt tatcgattta agaagtgata ctgttactat
    21781 gcctactgac gaaatgagag aagctatggc aaaggctcct gttggagatt caatctttag
    21841 agatgaccct actgtaaata aacttgaaga attagcagca gctaaagttg gaaaagaaga
    21901 tgctattttc cttccaagtg gaacttttgg gaatcaatta gctctattta ctcattgcct
    21961 aagagggcaa gaaataatta ttggtaaagg ttatcacatt gtgactcatg aggttggggc
    22021 acctgctgta atagctggag ttcagcttag aactatagat gaagacgaaa gtggagctct
    22081 aaatcctgaa cttgttgaaa aggcaattag aagagatgac atacatgaac cacagacagg
    22141 gcttatatgt gtagaaaatg catattcagg tggaacagtt gtgagtcttg ataatttaag
    22201 agaaattaaa aaaatagctg agaaacataa cttaccagta catttagatg gagcaagatt
    22261 atttaacgca gcattaactt tgggtgtaga agctaaagaa atagcaaagt gttgtgatag
    22321 tgttatgttc tgtgtgtcaa aaggtttagc tgcaccaatg ggttctatac ttgctggaaa
    22381 taaagaattt atagcaaaag ctagaagaaa gcaaaaagtt atgggtggag gaatgagaca
    22441 agtaggtata gttgcagcag ctggtataat tgccattgaa aaaatgactt taagattgaa
    22501 tgaagaccat gaaaatgcaa aatatttagc ttgtgaatta aataaaattg atggcattga
    22561 agtaaacaat gttaatccag atataagtat ggtatttttt aagatgagtg aagatattat
    22621 aaaagaggat gttttaataa aagaattttt tgaaagaaat ataaaaatta ataaaatgga
    22681 aaatggtgaa tatagatttg taactcatgt agatattact aaggaagatt tagactatgt
    22741 tttaaaaaca cttaaagaat taataggtgt atgttaatag atatctacta gaaggattat
    22801 agctagttac cagatgttta attaaaaaat tcatagacag tttaaataaa acatacataa
    22861 aattcatata gaaatattaa tatataaaca tagaaagaac tagcttaaaa acataatata
    22921 attaccctaa ttgtaatggc aactctccct cacatcctca aattatagtt gtcattacaa
    22981 aacttttccc ataaattata agtttatggg aattttttta tgttataata gtttaagtgt
    23041 taatttacga aggagcgata cttatgaaat tttggaaact acatggaata ggaaatgatt
    23101 ttatagcaat agatggaaga ttcgaccaga taaatccatc tgattatact gctttagcaa
    23161 aaaaagtatg ccatagaaga ttttctgtag gagcggatgg attgttagtt gtgaaagatt
    23221 caaaagttgc agatgtagaa atggtatatt ataattctga tggttcaaga gcagctatgt
    23281 gtggaaatgg ccttagatgt ttttgtaaat ttgtttatga taattgtata gttaaaaaag
    23341 aaagttttac agtagataca ttagatggta taaaagatat aaaagtaaat cttactaata
    23401 gagaaataaa ctctataaga gtcaatatgg gaaaaggaag ttttatagct aaggacgttc
    23461 ctgtacttac aaataaagaa cgttttgtgc aagaaagtat aaaggtttta gatagggagc
    23521 ttaaagttac ttctatgttg atgggggttc ctcatacagt agttatagta gatgaattag
    23581 atgtagatga tgtttgtaaa tatggaaaag agattgaaaa taataaaata tttcctgaaa
    23641 aaacgaatgt aaattttgta aaggtagaag ataagtataa tatacatgtt tatacttggg
    23701 aaagaggttg tggatatact ttaggttgtg gtactggtat gactgcatca gcaatagtgt
    23761 gcaatttact taatatggta gaaagtagtg taaatgtaac gtctcaaggt ggaacagtta
    23821 aaatagatgt aggagatttc tcttatatga caggtccagc agtaaaaata tgtgaaggta
    23881 ttttggaggt ttaattaatg gctataagta tgactggttt tggaagagga gaatacaagg
    23941 atgataatta ttacttttta gtagagtgta aaacgataaa tcataagtat tcagatataa
    24001 acatacgtct tccaagaaaa atttcatttt tagaggataa agttagaaat ttagtaaaaa
    24061 attatgtaaa aagaggaaga gtagatttat acataaagtt tgacttatta ggcaaagaag
    24121 atgtaaactt aaattttgat gagggattag catctcagta tatagacata ctaaaagaaa
    24181 taaaaaataa atttgatatt atagatgata ttagcgttat gaatgttgca aagtttcctg
    24241 atattgtgaa aatagaagaa aaggaagaag atgaagattt attgtggtca atgttgaatc
    24301 aagcagttga agatgcatta atcaaattaa gagaaatgag aagtgaagaa ggtaaaaaat
    24361 tagctgaaga tattgccatg agatgtgatt tattaaaaaa tcatatagaa gagattgaaa
    24421 aatattcaag tagtgttgta gaagattata gagaaaaatt gaatttgaga ataagtgaat
    24481 tactggatga cccaagtata atagatgaga atagattagc acaagaagtt gcaatatatg
    24541 cagataaaag cagtataaca gaagaaatag ttagatttaa aagtcatata gggcaactta
    24601 aaaatactat atttaaagac gactctatag gtagaaaaat agatttctta atacaagaga
    24661 tgaatagaga aactaacact ataggttcga agtcatctga tataaatata actaatttag
    24721 tagtagaagt aaaaagcgaa ttggaaaaaa taagagaaca aatacaaaat atagagtaag
    24781 aatacaatat tagaagggga atgcttaaat gtttgtgaaa aaaggattat tgctagttgt
    24841 atcaggacca tcaggtgcag gaaaaggtac tatttgcaaa gaactactta aagaaaatga
    24901 tacaataaaa ctttctgtat cagctactac aagaaaaccc agaactggag aagttgatgg
    24961 agtaaattat ttcttcataa gtaaggaaaa gtttgaagag atgatagaaa aaggtgagtt
    25021 tttggagtat gctcaaattt atgataattt ttatggaact ccaaaagcgg caataatgga
    25081 atgtttagaa aaaggacaag atgtattact ggagattgaa atgcaaggag caaaacaaat
    25141 aaaagaagtt tgcccagagg gagtatttat atttgtacta ccaccatcac ttaaagaatt
    25201 aaaaaataga attgttggaa gaggtacaga aacagaagct gaaatagaga agagatttag
    25261 ctgtgcatat gaagaaatta aaatgattaa ggattatgat tattttatat ttaatgaaga
    25321 tgtaaaaaca tctgctaaag aaatagaagg tataatatca tctgaaaaga ataaagttag
    25381 cagatataaa aatattataa tagagaaatt taaggaggaa ttataattat gttaaaacca
    25441 tctatcaatg aggtactaga aaaaatagac aacagatact atttagtagg gactgtttca
    25501 aagagagcaa gaaaattaat tgatggagaa gaaccatatg tttcaaataa aactaaggaa
    25561 aagcctgtat gtgtagcaac taaagaagtt gcaagtggaa aaataacata tagattattg
    25621 acagaagagg aaatagagat agaagaagct agacatcatg ctgagcaaca ccaacaaatt
    25681 tcagaagagg agtaaggtca tgctaaaaga taaaactgtt gtaattggca taagtggcgg
    25741 tatagctgca tataaggctt gtgatgttgt aagtaagtta aaaaaactaa atgcaaatat
    25801 ccatgttata atgacaaaat cagcaacaga atttgttaaa ccacttacat ttcaatcgct
    25861 gagtcaaaat tatgtagtag aagatatgtt tgaagaacca aaaacttggg aagttgaaca
    25921 tatatcatta gcaaaaaaag cagatttatt cttaatagtg ccagcaagtg caaatgttat
    25981 aggcaagatt gcaaatggta tagctgacga tatgttgaca actactgtta tggcaacaaa
    26041 agcacaggtt cttatagcac cagctatgaa tactaatatg tatgaaaatc caattgttca
    26101 aaaaaatata caaactttaa agagctttgg atataaattt attgaaccgg aaagtggaag
    26161 gcttgcatgt ggagatattg gaacaggtaa actagctaat ccagatataa tagtagagga
    26221 agttttgact aatcttacta aagagcaaga tttaaaaggt caaagtatga tagttacagc
    26281 tggtccaact gtagagagta tagacccagt aagatattta actaataggt cttctggtaa
    26341 aatgggatat tctatagcaa gagaagctat agctagaggt gctgatgtaa cattaatatc
    26401 aggtcctaca aatctttcta ttccacaaaa tcttaaaaaa tttgttcaaa tagagtcagc
    26461 acaagatttg tatgaagcag tagtatcaaa tttaagtgaa aataaaatag taattcaaag
    26521 tgcagcagtt gcagattata aaccaaaaac ttattctgac aaaaaaatta aaaagaagaa
    26581 tgatgattta tcaatagaac taagtagaaa ttatgatatt gcttatgaaa taggaaaaat
    26641 aaaagaagat aagatactaa ttggatttgc agctgaaact aatgacctta tagaacatgc
    26701 caaaggaaaa ataaaaaaga aaaatttaga ttttattgtg gcaaatgatt taactaaaga
    26761 aggtgctggt tttagagctg atactaatat tgtaaaaata atagatgtag agggaaatat
    26821 tactgagtat cctaagatga aaaaagaaga agtagccaat gttattttag ataaagttaa
    26881 agcgttgctt gagaaataag acctttttta aatatgatat ttgtgtattt tatcacagct
    26941 aaagtggctg aaagctgcaa tttaatttta gcgagtaaaa actcgcaaat gtcagttaaa
    27001 ttgtagtttt cagcatttat tttgtcataa agtataaaat ataattaata gttaattatt
    27061 aaaataaagt taatattaat aacttgaaat tgcttataaa ttctgagatt ttaatatctt
    27121 gtaaagtata ttaaaatatg aacaatatat taaatttaag tagaggtttt ataatgaaaa
    27181 aatatgcaaa ggtaatagtt agaagtaata ctatatatac agataattta tttacatatc
    27241 aaattcctgt atttttatct gatgtaataa aaattgggca cagaatatta gtaccatttg
    27301 gaaaaggtaa taaaccaaca gaagcctttg tatttcaatt tacagatagc ttagatgaaa
    27361 aaataaaaat aaaagaaatt attgatatat tagatgaaaa tccgatattt agaaaagaag
    27421 atttagagtt ggtttattgg atgaaaaata gatatttgtg tacttatata gaatgtataa
    27481 atttgatata tccaaaggga tacaaattaa ataattataa agtagtccta ttaggtgaaa
    27541 gtttaagtgg attaaatgat attgaattga aggaaaaaat atcaacttta agtgataaaa
    27601 atagagaaat agtagagaaa gtgattgata gtaaaggtaa aattaaggtt gataagttaa
    27661 aatatatacc aaacttaaat agttctttgt acacaatgaa taagaatgga attataaaat
    27721 tatgttggga atataaaaat cacaaaaatg aaaagaaggt atgttatata tctttgagtt
    27781 tagaaagtga taagattgac gattatatag agcaaaataa aataaatgtg ggaagtaaac
    27841 aaaaagagat attaagtttt cttaaaaata atgaaaatgt agagataaat gatttattgg
    27901 atttattaaa tgcttcaaaa caaagtataa attctctaag taagaaaaag ctaataaccc
    27961 tagaatttaa ggattattat agagagccaa aaagtattta caaatccgta ctaaaaagta
    28021 taaaattaaa caatgagcaa caagaagcag ttgatgagat aaagtcgaat atgtttgtag
    28081 atgataaaaa accatactta attcatggag taactggaag tggaaaaact gaagtttaca
    28141 tggaaataat agaatttgct ctaaatcaag gcttagacag tatattctta gtacctgaga
    28201 tagcattaac tcctcaaaca atagataggc taaagagtag gtttggagat ttggttggag
    28261 tgttccacag taaactatct gaaggagaaa aacatgatgt ttacaaagct gtcaaagcag
    28321 gtaaagtaag agtgttaatt ggagctaggt cagctttatt tgcacctttt aattccttag
    28381 gcttaataat aattgatgaa tgtcatgagt catcatataa gtctgagaag aatccaaaat
    28441 ttaatgctat agaagttgct agatttatgg cattaaaaaa taatataact cttattttag
    28501 gttcagcaac gccctcaatt gaagagtatt atagggcaaa atctggagaa tacaaactta
    28561 taaatataaa aagtagagca aatgataagc ctcttccaaa cattgaagtg gtagacatga
    28621 aagatgagtt agataaagga aatagaagta tatttagttt gaaattacaa aaagaaatac
    28681 gttatgcgat tgaagaaaat aatcaagtaa tactattttt aaacagaaga ggttatgcaa
    28741 attttgtatc ttgtagaaag tgtggatatg tgtttcaatg tgaaaattgt gatatatctt
    28801 taacttatca taagaaaagc aatactggaa gatgccacta ttgtggatat gagaaagaaa
    28861 ttccaaaaga gtgtcctgaa tgtaaaagta cttatgttaa gccatttgga gttggaactc
    28921 aaaaaattga agaggaatta aaatatattt ttccagatat aaaaactttg agaatggata
    28981 aagatacaac ttcaaaaaaa ggtgctttag atgagatact aaataaattt aaagataaag
    29041 aagcagatgt acttattgga acacagatgt taagtaaagg gctggatttt gagaatgtaa
    29101 ctttagtagg tattttgtct gcagacatga tattaaattt tccagacttt aaaagttttg
    29161 aaactacatt tcaattgata actcaagtct ctggaagagc agggagagct gataaagagg
    29221 gaaaagtagt acttcagact tatgacactg aacactatgc tattaagcat gctattgaat
    29281 atgattatga gggtttttat gaagatgaga taaaaataag aaaagcattt ggatattctc
    29341 cttttaataa tatgttaagt gtagttgtta gtggtgaaga tgaaagacta gtgataaaaa
    29401 atataaaaaa tatgcatgca tcattgattt atttattaga aaaaaggggt ataaatgatt
    29461 taggatttat attaggtcca aatccatgtt caatatcaaa aataaatcaa aattatagat
    29521 ggcaaatact ctttaaagat gaaaatattg aaattaatct cttaaagggt ataataaaat
    29581 atatatgtat aacaaaacga gatttgatat ttgataagaa tatcaatgta tctatagata
    29641 ttaatccaaa cagtgtatta taaatttagg aggaattata atggctttaa gacaaatagt
    29701 tcaaatagga gaaccagtat taagaaaaaa atcaaaaaag gttgaaaaaa ttgatgaaaa
    29761 gataatacaa ttattagatg atatggcaga aactatgtat gatgcagatg gtgttggact
    29821 ggctgcacct caagttggaa tattaaaaag agtagtagta atagatattg gagaagagct
    29881 tatagaactt ataaatcctg aaataataga aacatctggg gagcaaatag atgaggaagg
    29941 atgtttaagt gttgttggag aagcgggaaa tgttagaaga ccaaattatg taaaggtcag
    30001 agctttaaat agaaatggtg aaacaataga gttagaggga gaagaacttt tagctagagc
    30061 attttgtcat gagatagacc acttagatgg aattttgttt gttgacaaaa tagaaaagta
    30121 gtaggagttg atttgatgaa aatagtattt atgggaactc ctgatatagc agttccatgt
    30181 ttacaaaaaa taatagatga gaagtatgaa atattgggtg ttgtaactca accagataaa
    30241 ccaaaaggaa gaggtaaaaa actaggtatg agtccagtaa aagaactggc aattgaaaat
    30301 aatatacctg tatatcaacc agtaaaggct agagataaag aatttataga taaaattaaa
    30361 tctttaaatc cagatgtaat agtagttgta gcttttggac agatacttcc aaaagaaata
    30421 ttagagattc ctaaacttgg atgtataaat gttcatgttt ctttacttcc aaaatataga
    30481 ggtgcggcac ctataaattg ggtaataata aatggtgaag aaaagactgg tgttacaact
    30541 atgtatatgg atgaagggct agatactgga gatatgatac taaagacaga agtaaatctt
    30601 gatgaaaata taacagcagg agaacttcat gataaaatga tgaatatagg cgcagaaact
    30661 ttaaaagaaa cattaagatt aattgaagaa ggaaatgctc caagagaagt acaaaatcat
    30721 gaagaatttt cctatgcgcc aataatgaat aaatcattag gtaacataga tttttcaaaa
    30781 agtgccagag aaatacacaa tttagttaga ggagtaaatc catggccaag tgcctatact
    30841 acctataatg atgtcataat gaaagtttgg aaaactaaag tgttagatga aaaaagcaca
    30901 aaagatgtag gtacaataat tgatgtaagc aaagatggga taaaagtaag tactatagat
    30961 aatgtacttt taattgaaga aattcagatg ccgaataaaa agagaatgtt ggttggtgaa
    31021 tatataaaag ggaatactat agaaactggt ttagtattgg gttaggtgaa aagtatgaca
    31081 gatataaaga agtatttaac aagtgttggg attttgattt taatattagg aattttgata
    31141 ggagttgtta atttttttat aataagttta actcaaatat tctccttgat gataaatatt
    31201 ataataatat cactaatact tataatacta tgttcaacag cagttactta tagagtaatt
    31261 aaaggaaagt atgttaactc aaatataatg aaaataaatt ttaatattgt cagtggatta
    31321 tttcctatta tatctttcat tgcatcatca tttggtatgt caaaaagtga tattagaaga
    31381 atatatataa agttaaataa tgaatatata tacagtaata aatataattt taatccagag
    31441 gatataataa ttttaatacc tcattgtatt caagagaata gttgtaaatt aaaagttact
    31501 aatgatatag ataattgtaa agaatgtgga agatgcaaca taggagaatt aattaagcta
    31561 aaggaaaaaa ctaatgtaaa aatatttgta gctactggag gaaccctagc tagaaaaatt
    31621 ataatggata ataaacctaa agctgttgta gctgttgcat gtgaaagaga tttgacatct
    31681 ggaatacaag atattaagaa aattcctgtt ttaggtgtat ttaacaaaag acctaatgga
    31741 ccttgtgtaa atactaatgt agacattatg gatattgaaa aagctatagg ctttttaaca
    31801 ggaaaaaata tattagtttg taattaaact gtttttaagt gaagtgaata ttaagaggat
    31861 gtataataaa aatatatttt aggagagtgt tatttatgta ccctgtatat ggcggttttt
    31921 ggggatttga cccaacaatg gttgtattaa ttccagctat attacttact atatatgcac
    31981 aatttaaagt gagttcaaca acaaataagt atttaagagt aaatacacgt cgaggatata
    32041 ctggagagca aacagcaaga agagtacttg attcaaatgg tttgtatgat gtaaagatag
    32101 aaatggttag agggcatcta agtgaccatt atgacccaag aagaaaggct gtaaggttgt
    32161 cagaagatgt atattatgga acatctataa cttctgttgc agtagctgca catgagtgtg
    32221 gtcatgccat acaacatgct aaaggttatg cacctcttca aataagaagt agtttagtac
    32281 cagtagtgaa ttttgcttca agtatatctt ggtttttaat atttttagga tttattatgg
    32341 ctggtccatt tttaaaaatt ggtatactat tgttttcggc ttcagtgtta ttccaaataa
    32401 taacattgcc tgtagaattt aatgcttcaa gtagagcaat cgttcaactt gggaatttag
    32461 ggattataga tgaaagtgag tcaagacaaa gtagaagagt actttcagca gcagctttaa
    32521 catatgttgc agcagcattg gtttcaatac ttcaattact tagattgtta ctaatagctc
    32581 aaagaagaaa tgactaaaag taaagtgggt tgtttagaaa caaccctttt ttatgtttaa
    32641 taaaagggag aaatttatat ggatgcaaga gaagttggat ttaaagtatt atgtgatata
    32701 gaaaaaaatg acaattattc aaatattgca ataaataagc attttaaaaa tttagaaata
    32761 agtgatatgg atagaggact tgcaacagag ttaatttatg gagtaataga aaataaatat
    32821 tatttagatt atataatcaa taaactttca aaaataaagg taaaaaaaat gtcaacttat
    32881 gttaaaatct ttttaagaat gggaacatat cagattttat ttttagatag tatatcagat
    32941 tatgcagcag ttaatgaaac tgtaaaatta tctaagaaat atgataaaaa atcttctggt
    33001 ttcataaatg ctattcttag aaatgaaata agagctaaag agactataat ggacataact
    33061 gaggaagata gtgtaaaata cttatctata aagtattcct ataactcttg gattataaaa
    33121 aactggatag ataaatttgg acaagaattt gctgaagatt tgttggaagc aaataatgaa
    33181 aagcctagta tctatataag aacgaataca cttaaaataa gtagagaaga acttattgaa
    33241 aaattaagtg aaatgggtat tgtatgttta aaagttccta tggtagaaga agctattaaa
    33301 gtcgaaaaaa tgaaaaatat agaaaaaaat gaattattta aggctggttt atttacaatt
    33361 caagatataa gttctatgat agtagggaaa gtaattaatc caaaagaagg ttcatttgtt
    33421 ttggatgtat gtagtgctcc tggagggaaa tctactcact tagctacttt aatgaacaat
    33481 actggtcaag tagtagctag agatattttt gagcataaac taaagcttat aaactctact
    33541 gtaaatagat tggggcttaa aaatgtgttt gtagaaagat ttgatgcttc tgagattgat
    33601 gaaaatagta taagtaaatt tgattatgtt ttagcagatg ttccttgctc tggttttggt
    33661 ataataagac gtaaaccaga aattaagtat aagaaagaag aagagttaaa agacatcact
    33721 tctatacaaa agaaaatttt agaaaatgca tctaaatatg tcaaagttgg tggaacttta
    33781 gtatatagta catgtacaat tcaagatgtg gagaatataa atatagttac ttcttttgtt
    33841 gaagaaaatc acaactttga atttgttcca attgatacag taaatgtaga cttagacaat
    33901 caagataaag gatatttaaa gatatatcct aatattcatg gtatagatgg ttttttcata
    33961 gcaaaattaa agagaataag gtagtgagag aatggaaaag aaaaagatag tattaaaaaa
    34021 ttttactgaa gatgaactta aagagtttat gaaaactata gatgaaaagc cctttagagg
    34081 aagtcaaata ttctcttgga tatataaggg tgcaaaaact tttgatgata tgaacaatat
    34141 accaaaaagt ttgagaaata aattagaaga ggtttcatgt atagggcata tagatataga
    34201 attaaagtta gaatctaagg tagataatac aaaaaaatat ttgtttttat tagatgatgg
    34261 aaatataata gaaactgtga tgatggatta tgatagtaga gttactgtct gtgtttctaa
    34321 ccaagtaggt tgtaggatgg gatgtaattt ttgtgcatct acaatggatg gattaattag
    34381 aaacttagag ccatgggaaa ttttagacca agttattaaa attcaagaag atactggtaa
    34441 gagggtatca aatcttgtat tgatggggag tggtgagcca cttgataact ttgaaaatac
    34501 aaaacaattt ttaaaaataa ttaacgaaaa aaatggtctt aatatagggt atagacatat
    34561 aactctttca acttgtggaa tagtacctaa aatgtatgag ttggcagact tagaaatagc
    34621 tataaattta gctttatcac ttcattcacc atatgatgaa gaacgaagaa aaattatgcc
    34681 tgtagcaaat gcttattcta ttgaagaaat attgaatgca tgtagatatt atataaaaaa
    34741 gacaaataga agggttacat ttgaatattc tcttataaaa ggagtaaatg actcagaaaa
    34801 agaagcaaag gcattagcta agctcctaaa aggtatgcta tgtcatgtaa atttaattcc
    34861 aataaataaa gttgaagaaa gagaatacga aaaaccagat aaagcattta tttataaatt
    34921 tagggatagt ttggagaaga acaatatacc tgccacagtt aggatgtcta tgggttctga
    34981 tattagtgga gcttgtgggc aattgagaag aaaatacaag taatttgtaa ggaggaagtc
    35041 gtatggttta tagttgtgcc tcccatatag gaaaaataag aaaaaacaat gaagactatt
    35101 gtgagggaga agttatagat acagaacatg gtccaatagg aatatttgcc atagctgatg
    35161 gaatgggtgg acataaaaaa ggtgaagtcg ccagtaaatt agcagtagaa aatataattg
    35221 attttctaaa agaaaactta ttacaacatg ataatgtaaa aatagactat atagatgata
    35281 tattaaaaca ggcttataat aatgtaaact caattgtgca caaaaaatct atggaagata
    35341 tagaatttga aggaatggga actacattag ttacggctat agtgtataat aatgtcttat
    35401 atgtggcaaa tgttggagat agcagatgtt atttgttaac agatgaaaaa tttgataaaa
    35461 taactataga ccattccgtg gttgaagaac ttatgatggc ccatgtcatt acagaagaag
    35521 aggcaagaag acatccacag aggaatagaa taactagagc aattggaaca gatgatatgg
    35581 ttgttgtaga tatttttaag aaagaaatca aaaaaagtga tataatactt cttgcgacag
    35641 atggattaac tgggtttatt gatgatgaag atataagaga tttaatatta gattatgaat
    35701 atgagagaac tagtaatata agtgaagaat tgataagtat ggccaatgat gtttctggta
    35761 aagataatgt ttcggttata gtgataaaag tataattagg acggtgatat tgtgggagat
    35821 acaattttag gaaatcgata tgaaatcatc aggaagattg gtgatggagg aatggccttt
    35881 gtatatgagg ctaaagacag attattaaac aggactgttg cacttaaagt acttagacct
    35941 gaatttgtag atgatgatga atttctaaca aagtttaaaa gagaggcaga agcagtagca
    36001 agtctttcac atccaaatat agtaaatgtt tatgatgttg gtgaagatgg aaaagttcac
    36061 tacattgtaa tggagtttgt agatgggaag aatctaaaag agattataca agatgaaggt
    36121 atattagatg aatatactgc attagatata acaaaacaaa tagctatggc acttagtgca
    36181 gcgcacaaaa aggggattat acatagagat ataaaacctc ataatattct catatcaaat
    36241 gaaggaagag tagtaaaagt ggctgatttt ggtatagcca aagctgtttc aaattcaaca
    36301 atgactaata ttggtagtat aataggttca gtgcattatt tttcaccaga gcaagctaaa
    36361 ggtaaatttg taactaataa tgctgacctg tattctctag gtatagtttt atatgaaatg
    36421 ttgataggaa aagttccatt taggggagat agtccaattt ctatagcact tcaacacatt
    36481 aatgatgata tagactttac atcagaagaa aaagttagga ttcctcaaag tgtaagaact
    36541 acaataaaaa agcttacaga aaaatctagt gcagatagat atcaaactgc tgaagaattg
    36601 atagaagata tagagtatat agaaaaaaat attgatttag attttataaa agaatatgat
    36661 gattttgcaa ctaagaaaat tgatgaaaaa gaaattaata aagttgtaaa tccaacactt
    36721 gcaaaaccag ctcctgaaaa agtggttaag cctgttgaag tagctgattt ggatgatgat
    36781 gaagattact atgatgattt ttatgaagaa gatgatgatg aagatgaaga agaggaagag
    36841 ataatgagag ctaaaaagaa tcagagacct aagagtactc caagtaagag aactaagaaa
    36901 aagaagaaaa aacaggaaag cccaaaatct agaagaagat taaaagtaat tgcggctgtt
    36961 ttgatactga tattgtgtgc tcaagtattc ttagcatata agtttttatt tgctggaggg
    37021 tttggcaata aatctttgac tgttcctaat cttgtaaata tgacattaga agaagctcaa
    37081 agtgctgttg aaaaagaagg attatacctg agtgtaaaaa gtgaagagta taatagtgaa
    37141 gttgatgaaa attgtataat atcacagaca cctgaaggtg gaagtacaaa tgtcaaaaag
    37201 ggtgatacta taaatgttgt cgtaagtaaa ggttcaagtc aggcatctgt tcctaatgta
    37261 gtgggactta ctttgagtaa tgcaaaacaa cttattgaag aaaataactt aaaagtggga
    37321 actgttaagt atgaatacag ctcaatatat aaagaaggta cagttttaag tcagagtccg
    37381 ggtgctggct catcaagagc tcaggaaggt gatgaggtaa acctatatgt aagcaaaggt
    37441 tcagaaaaat caaatacaca gactccaaca gtaccagata aaaaaccaac aacaccagag
    37501 aataatacac caacagaacc tggttcaaac tcaggaaaca gtggtggaaa ttcaggaggc
    37561 tcaaattcag gaaatagtgg tggaaactca ggcaataatg gaagtaactc aggaggttca
    37621 aactcaggaa atagtggtgg aaactcagga ggctcaaact caggagataa tggaggaagt
    37681 tcaggaggct caaactcagg agacaatgga ggaagttcag gaggttcaaa ctcaggagac
    37741 aatggagata gttcaggagg ctcaaactca ggagataatg gaggaacttc atcaggaact
    37801 ggcgcaaaca ttggtaaaac agaataaata ttaataaaat aagagctgtc cttttataga
    37861 aaatattttc tttaaagggc agtttgtttt gtataaaata ctgaattggt tataatataa
    37921 ggagaaaagt atttatgaag aagaaaacag ttttaattac aggaggagct agagggattg
    37981 gtaaagctat gtctaaagct tttgcaaaag aaggttacaa tgtattagta aattttaata
    38041 agtcagaaaa tgaagctaaa gagttgtaca ctatattaaa tgaaaaaaat ttttctgtaa
    38101 aactttttaa ggctgatatt tcaaatagag aagatgtaga ggatatggta gattattgta
    38161 taaaagaatt tggaggattg gatgtacttg taaacaatgc tggtgtaagt caagataagt
    38221 tgtttacaga tataactgat gaagattggg ataatatgat gaatattaat ttaaaaggaa
    38281 gcttttattg ttcacaagtt gctttaaaat acatgatatc agaaaaaaaa ggaaatataa
    38341 ttaatatatc ttcaatctgg ggtatatcag gtgcgtcttg tgaagtgcat tattctataa
    38401 caaaagcagg cataataggt atgacaaagg cattagctaa agaagtagga ccatcaaata
    38461 ttagagtaaa tagcatagct ccaggtgtca ttaatactga catgttatct ggatataatg
    38521 aggaagatat agacgctctt gtggaagaaa cccctctaat gaggctagga actccagaag
    38581 atatagcaaa ttgtgctatt ttcttggcat cagacaaatc aaattttatc actggtcagg
    38641 taattagtcc aaacggagga tttgttattt aaaaaaaatg tggtattata taaaaatagg
    38701 aaagaataac acgatatact actcataaac agtatgtgtt tatataaatt ttataaaggg
    38761 aggcatttga tgctagaagg aaaaattata aaggggatta gtggatttta ttatgtagat
    38821 acttataatg gtatttatga atgtaaggct agagggatat ttagaaagca gaaaataaca
    38881 cctttggttg gtgatagagt caaaataagc attgttgatg aaaatgaaaa aaagggtatc
    38941 ttagaagaaa tcgacagtag agatacagaa cttataagac ctcctattgc aaatgtagat
    39001 aaagcattaa tagtattcgc aataaaaaat cctaaaccaa acttatctct tttagataga
    39061 tttatagttt tggcagaaaa agaaaattta gaaactgtaa taatccttac aaaagcagat
    39121 ttagatgata atgatacatt agaaactgtt aaaaatatat atgaacttag tggctataaa
    39181 gtcattcctg taagcaatat tactaagtta aatatagata aagtaaaaga agaattaaaa
    39241 gaaaatgtag tagtgtttgc aggaccatct ggagttggaa aatcaagctt attaaatgaa
    39301 atagatgaaa attttaaact tcaaacagga gttgtaagtg ataaaataaa aaggggaaaa
    39361 catactactc gtcacgctga acttttaaaa ttagaatttg gtggaatggt tgcagataca
    39421 ccaggtttta gttcccttgc ccttgaagat atagaggaag ttgaacttaa agattatttt
    39481 atagaatttg ataaatttaa tgattgtaag tttggttcaa agtgtattca tgaaaatgaa
    39541 cctaattgtg ctataaaaga agctgttaca aatggagaaa tatctaaaga aagatatgat
    39601 agttatatac agctgctaca tgaaataaga caaaataata gtaggaggta ttagaaacat
    39661 gattaaatta gcaccatcaa tattatcagc agattttgca aaattattag aagatgtaag
    39721 aaaagtagaa agtgcaggat gtgaatatct tcatatcgat gtaatggatg gacactttgt
    39781 accaaacatt acattaggac cacttgtagt caaaagttta aagaaagaaa atataaatat
    39841 ggtatttgat gctcatctta tgatagaaaa tccagaccag tatattgaag aatttgtaaa
    39901 agcaggatgt gatataataa ctgttcacca ggaggcttgt gttcatctac atagaactat
    39961 acaaaatata aaatcacatg gaataaaagc tggtgtagta cttaatccag ctacaccagt
    40021 agatacgatt aaacatgtac tacctgattt agatatggta ttattaatgt ctgttaaccc
    40081 tggatttgga ggacaatcat ttattccttg tgttttagat aagattaaag agttaaaagc
    40141 tattatagat agtcaaggat taaacattga tatagaagtt gatggtggta taagccctaa
    40201 aaacgtagcc gaagttgtac aagcaggagc taatgtaata gtagcaggtt ctgcaatatt
    40261 tggaagtgat gacattcaag aaacagttaa tttatttaga aagaatgctt ctcttgaaga
    40321 attagtttaa atttaataat gaaaatctgt attgttttaa atggcgaaat tgaagattac
    40381 gaagttacaa gagatattat aattaaggaa tgttatgact gcataatatg tgcagatgga
    40441 ggggcaaatc acacttataa aatggaaata atgccagatt atatattagg agatttagat
    40501 tcagtagaag aagaaaagat aaacttctat aaaaataaag gtgttaaatt tgaaaaattt
    40561 ccatctaaaa aagatgagac tgatacagag ctttgtcttt ttttagctaa gacacttaaa
    40621 gcaaatcata ttgatttttt tggtgcttta gggggaagga ttgaccacac tcttgcaaat
    40681 ataaagctat tatattattt aaaagaagat ggtatatatt ctaggatact ttctgataaa
    40741 gaagagatgt atatagttga aaatgaggaa atttcattgt atggaaaccc aggggacact
    40801 atttctgtaa tagctataaa tggtgatgct aagggtgtaa cacttactgg cttagaatac
    40861 cctctcgata attattatat gaaatactct gtacctattg gaatatcaaa tgttatgttg
    40921 agtaattctt gtaagattaa agtagagcaa ggctgtgtac ttgtagttag aaatttataa
    40981 aatttgattt tgacaattgg ttttatattg tagagcagat acaatcaagt aaaatatatt
    41041 tatgattgta tctgcttttt agtatataat tataaatata taataaactt tgacataagg
    41101 gggatttttt gtggtagata gtattatttt tgatttagat ggaacattgt gggattcaac
    41161 tgaagaagta tgcaaagtct ggcaggatgt tttaagtgag cataaggaaa tagaattaag
    41221 tgtcacaaaa gatttattta gaagtcttat ggggctttct tttgaggaaa tagcaaatcg
    41281 tttatttcca aatttaagtg aagaagaaag aatgaattta ttgaatgaat gttctttgaa
    41341 agaatgtgac tatttatctg aaaatggagc taaattattt gatgatatag aagatactct
    41401 taaattacta tctaaaaaat ataaattatt tatagtaagt aattgtcaag ctggatatat
    41461 agaatctttt ttaaaagcac ataaactaga acagtatttt atagattttg aatgtcctgg
    41521 taatactggt ttgcataaag gagaaaataa taaacttata attgaaagaa ataaattaat
    41581 aaatccaatc tatgttggtg atacgcaagg tgatgcaaat agtgctaagt ttgtaggtat
    41641 accttttata tatgccaaat atgggtttgg gaatgtagat gtatatgatt attttataga
    41701 ttcatttaaa gatttgttag aacatgatat attaaaataa gatgagttta aaaattatat
    41761 taaaataata aaaaagttat ggggggattt aaaaatggaa ttacaagata ctatttttaa
    41821 aagacaaagt gtaagaaagt ttaaaaatca agatgtatca gatgaagata ttttaaaaat
    41881 gataaaagca gcaggtgcag caccatcagg caagaatatt caaaactggc attttgttgt
    41941 tataaaacgc cgtgatttaa tggaaaagat agcagatgtg ataactaaaa agcaacaaga
    42001 aatacttgta gaaatggata aagtatcagt ggataaggct aatagattta gaaaatttgt
    42061 taaaaatttt acactatttt acttaaaagc tccagtttta gtattagttt ttacaaaggt
    42121 atataatcca tcaggatatt atgaattaga gcttatagat gcacctaagg agactataga
    42181 taaattattt ataagaaatc caggtatgca gagtctaggt gctgcaattg aaaactttac
    42241 actatcagca attgaacttg gatatggttc ttgttggttg acaagtcaaa actatgcagc
    42301 agatgagata gaagctgttt tagaagcaga aactggtttt gaaaagggag agtatttttt
    42361 aggtgcaatg ttagctcttg gagtgccaga ggacaatttg aagagtccat ctaaaaaacc
    42421 agtagaagaa atatgtacat ttataaaata aaagtcaagg acattttaaa atcgaagtaa
    42481 attaaaaaca aaataaatta aaaataaata tttaaaaaat taaaaagtag gttttattga
    42541 tattaatttt atatttcaaa tcattgattt aattaataca ataagaacta ctttttttgt
    42601 atattaattt taaatatatt taaatcttta gaaaatcttt agaaaagtat atgtaatatc
    42661 ttaagttttt aattttaata ttaagtatat aaaacaaaat gaaaaaatat taaatttaaa
    42721 ctagaaggag gtttctaaga tggacattaa atacaaataa ccagaacaaa agatataaat
    42781 atatatataa atggaaaaac ttctatcata ttgtataatc atatatgtaa agaaaattta
    42841 taaattaata taaaggagat tagaatgaat tcatataata ttttggtggt agaagatgaa
    42901 aaggagatag cagatgctat agaaatatat ctattaaatc aaggatataa tgtttttaag
    42961 ggatacaatg gattagaagg tcttaaggtt atagaaaacc aagaaataca tttagctata
    43021 gttgatataa tgatgcctaa aatggatggt ataacactta caatgaagct tagagaaaac
    43081 tataattttc cagtaataat gctatctgca aaatcagagg aagttgacaa aataatgggg
    43141 cttaatatag gagcagacga ttatgtaaca aaacctttta agccattaga actattggct
    43201 agagttaatt cacaacttag aaggtacact aagtatctaa acatggttgg aaataaagag
    43261 caaaaggtag aaagtgacga tagtgtgttt gcaataggcg gattagaatt aaatgaaaat
    43321 acaaaagaag ttagtattga tggaaagtat ataaaaacaa ctcctataga atttaaaata
    43381 ctaagtttac ttatgagaaa tgcaggaaga gttttttctg ctgatgaaat atatgaaaga
    43441 gtttggaatg agaatgctgt aaatacagat acagttatgg tacatgtgag gaatataagg
    43501 gaaaagatag aaattgaccc aaaaaatcct aaatatttaa aggtggtgtg gggtgttgga
    43561 tacaaaattg aaaaaattta aagataaata tatagttact attatagttt ttatacttat
    43621 gttatcagca tcattaggta tgattagtca atattctact atacaagcaa gtgctaaagg
    43681 tggagcagag aatccatttg aacaggaaag ctttgtagat agtatatata aaggaagtta
    43741 tgttttatat cataatatga aggaagaaca agaaggtaag atgatacaac catcaaaact
    43801 atttatcaat gaagaaacta tgaactatat aaaaaatgta agtaaagaaa aagatactta
    43861 tgatggttca gaaacttact atacagatga tagtattaat gcagatttta atgaaaactt
    43921 tgaaaattgg gagcatttca ttaaagcgtc aggaaagaat ttaaagtact atttagttga
    43981 taaagaaagc aattttgaat tttttaatga taataaagaa ttaggagtac ttgatacaac
    44041 aaaaaatgat gcttcaaaag aaaattctga tgaaaatcag tcaaaaaata cagaaatgaa
    44101 tgatgaggaa agacaaaagc agattacaga tataaaagaa aactatagat tctacgttgt
    44161 aatgaatttt gataaagatg gaaaagtaaa tattgtggat tcttatggag taaatcaaaa
    44221 aattattaat caaatgttgt tatctaaagc aagagaagat ttaatggata caagtttagg
    44281 aggaaattca atttcatata agttatctcc aataaaaaat ataacattag tatatgctgt
    44341 acctaaagta ataagtaaag gtgatagtgt agagtatggt tatggaaata cttattttga
    44401 tgatggtata atttcatata taagcaatgt agaaaataat tcttattata agatttctgg
    44461 aatgatttta aaaattatat tagctatagt tgttattgta gctttagcat tcccatatag
    44521 aaaatctaaa gagttgctag gatttgatac attatcaaga ataccgttag agatactctt
    44581 tattgctctt gctattatac aggggcttgt agatttatat cctactgtta taataagtaa
    44641 taccttgagt gggaattatg tagagtacct tataaacaat gacataagtg ctaaaatggc
    44701 tagtatattg gtaagtttaa tgaatttaac ttattggttt gtaatattct caataatatt
    44761 tgtatttata atacttttaa aacatatttt aaatgttgga ataagagagt attttacaaa
    44821 acatactgtg acaggaatgt tttttgtatg gctaaaaaaa gcaggaaaaa cagttattaa
    44881 tcaaattaga acaataaatc taaaagaaaa gccaaataaa actatagtta caattttggg
    44941 aataaattta ttgattatag ttataatgtg tagtatgtgg ttctttggaa taatactcgc
    45001 attaatatat tcagtagtat tatttaaaat actgtcagat tactctaaaa agacaatata
    45061 tgaatataat caacttttag atgttacaaa gaaaatttca gatggaaact tagatgtaaa
    45121 tatggaaaaa gatttaggat tttttaatcc tataaaagac gaattaggaa atattcaaac
    45181 tggatttaaa aaagctgttg acgaagaggt taagagtcaa aagatgaaaa cagagcttat
    45241 atcaaatgta tcacatgact taaaaacacc tctaacatct ataatcactt atatagattt
    45301 attaaaagat gaaagtataa cagatgaaaa tcgtaagttg tatattgata cattagacag
    45361 aaagtcacaa agattgcaac atctaataga agatttgttt gaagtaagca aggcaaatag
    45421 tggagatgtt tatttgaata tagtaaatgt ggatattgta tctctaatga agcagacact
    45481 tttagaatta gatgacaaac ttgcagattc atctctaata gtaaagaata acttttctaa
    45541 tgaaaaaata atattaccat tagatagtca gcgtacattt agagtatttg aaaatcttat
    45601 aataaatata agcaaatatg caatgccaaa ttcaagagtg tatattgata ttttagaaac
    45661 agataataaa gtaaatatta tgcttaaaaa tatgtctgca tctgagattg attttagtgt
    45721 agatgatata atggagagat ttgtaagagg agataaatca cgtaacacag aaggttctgg
    45781 tcttggttta gcgatagcaa aaagttttat agaattacag ggtggtaaga tgaatataag
    45841 tgtggatggt gatttattta aagttacaat tacttttaac aaaaattaga ttagacttct
    45901 ttaataatta taaagtctat aggataaaag agtctggaaa tatttatgtg tattctttaa
    45961 ataaaaattt ataggtattg ttttaaaata atttgtaagc attatttcaa aacagcttat
    46021 aaatgttatt ttaaaacaga atgttgattt atttaaaaaa ggtgaatcct aatatacaag
    46081 gttcaccttt ttattttaca aaatgttatt tagtgttaca gagcttataa atagcataat
    46141 atctggcttt actattaaca tggtactagc aatttatttt gaaatcttgt ataagctatt
    46201 ttatattatt taattactat tgtttgtact ttacaatgtg ataaagaatt tacctctaca
    46261 gttttagtat ttactttaag cttgctagta ttatcataga tttcgtcgag cattgcacta
    46321 taagcatcat tgacattttt attgatgtta agacttccct tagcatcctc atttttcata
    46381 ccattgaaga ttctaactac aattccatct cctttttctt ctttctttat tgcacttact
    46441 gtgaaatttg aattatttac attcatcaaa ctaaattcat tttcatatat ttgtttttcg
    46501 tcattgaatg caaatataag tctaccattt aaaaaatcag catattcata tatttgtata
    46561 ggtgttaaga atctcttagc tgtattagct acatttgctt catcaaattt attgttatat
    46621 atgtaaagac caaagtcaaa gtttaactct ttaagtaatt gtgcatctgg tgttgctatt
    46681 attttttctc cagaagctct tcctggtcta taaagtaaat tttctcttcc catatatcca
    46741 aatgacctga atagtgttaa tgctattgta tctaaattat caccaactat ttgatattct
    46801 cttacacaac cagttattaa tgctattcct ctttgtccat cctctaaagt aacaaaactt
    46861 tgcattggtt cgatagttat aggtttttct tgccatgagt aattgtctct tttccacaat
    46921 gcaaggtctt tttctaatac tgttggtctt tgtattattc caaattgttg atctgctata
    46981 gaaaacttag atgctatttc tgtattaaat aaaactctta ctctatgaga tagtgcttgg
    47041 ttatttttta tattaacatt aaacttaatt atttgttctt taggttctaa ggtgattttc
    47101 attgttactg gcattttcac agaaacttta cctatagccc tttcttccag tgaagctggt
    47161 atggtcaatg aatatttaag tatcatttct tcttgaatgt ttgattttag cacttctact
    47221 gaagatacag aatctaaaga tgaaacataa atatcttttc ttggaggaga atagttgtat
    47281 gaatctccat catctccatt gtcttcaatt acagcttggt ttttataagt cttattagat
    47341 tctttatcta atatttctaa tgaaccattt ttattggctg ttattttgta gtatttgttt
    47401 tctatttcct tgcaattact tgtttctatt tcacatttat ttttagtatc caattcaaaa
    47461 actagttgag tatatcccat tggtggtata tcttttactg aaagtgcaat ttttgctcta
    47521 tatacagttt tgggtatata tattttttta cttgggttta atcttattgt ttgagttaat
    47581 atataatttg taatatcttc tttttctttt attatataat taagaatttt tccattttta
    47641 ttctttatca caaaatcttg acctggaata taagtatcaa attctacaac ttcatttctg
    47701 acttctggga atccattgaa tactgttaat gttatttctt cattattatt tttgatttga
    47761 gtacttataa gtctcatatg caaatctaat aaatttatac tcaaatctct ggcttgtttg
    47821 tatcttgtgt atacatcctc atttgttgtg tcactattac aagaacctat gctgtcatga
    47881 gctgcatttt caaacataag tttccatata tcttttataa ctaggtgagg gtattcattt
    47941 ccaagtgaat aacttaatgt taataacggt tcaagtacat ttgtaatata attttctaat
    48001 ttgttattca ttattttaag gtctgacctt gaggagaata tggatttgtg tattctcata
    48061 tgtttagcat ttaaaaattc acctttaagc tctgtaaatt catttctttc atttcttact
    48121 gaatctatat agttttctat atcacttatt tcgtattcat tttcattatc tatttcatta
    48181 gcttttttta atatatcagg aaggtttttt cttattggtg cttggtcaaa tccatttgga
    48241 aaatatacgt tattagtaga agctttaacc ttaagtttta cgattatatc ttttaaatat
    48301 tcttttaaat ctgaatcatc ttctggtata ttacctccat agtaataacc aaatggtatt
    48361 tgaactgcta atacttttga accatcagaa cctttccata taaactctgt tgtatctacc
    48421 atatcatcag aaactccacg ccaaaataat gaactatcta ttccaaaacc tctgtatatt
    48481 tgtggcattt gagctgattg cccaaaagaa tctggtacat atccaaccct cataggttca
    48541 ccaaattcat tgcatctatc tattccatag taaaggtttc taattataga ttctcctgat
    48601 ataaccaatt ggtctgtttg agtataccaa ggtccaataa ctaatcttct tctttgaact
    48661 aaatctctta ttctatattt atcctgaggt ctccatttta aataatcatc taagagagaa
    48721 gcttgtgcat ccatagtaaa gtatttaaag tcttcttttt cttccaatat gtctaatata
    48781 tcttgaaaat ctttcattaa atatattttt gaccttgatg ttgtaaaata ccattctcta
    48841 tcccaatgac tgtgtggaac tacatgtact tttgtctttt tcataaaaat cctcccaaaa
    48901 tttaattgag aattgagagt acactcaatt ctcaattatc taaaattaag tttttaattt
    48961 acattatatc taactctatt tcatcaaatt ctgtattttc cgtagtttca tcttcattga
    49021 agtctactaa agttgttgat aatattgcta ttactaaagc tccaaatatt gcacctacta
    49081 agtaagccca tccagaacct attgatataa atccatataa tccaccaact ggaggcatta
    49141 tagcatgtac acctaacaaa gctgataatc ctacacccaa agcgcatcct atcatattaa
    49201 caggaactaa ttttaatgga tttgttaaag tgaaaggaat tgcaccttct gttattccaa
    49261 ttatacccat aactatattg ccttttcctg tttcagctaa tgcattggaa aattttgatt
    49321 ttcttatgaa tgtagctaaa ccatatccta gtggaggtat aactattgcg cagtttacca
    49381 atatcgctgg tagatagatt ccctctaaca ataatgcatt tcctgccatc caagctgctt
    49441 tatttactgg tccacctaaa tcgaatccta tcattgcgcc taaaattaaa gccaatacca
    49501 ccgaatttgt tccattttga cacatttcag ctacccaagc atttaatgaa gtatttatgt
    49561 ttcctaaagg tcctgctaat acaacactca ttaaaaaacc agttaatcca actgttataa
    49621 gtggcattat tataagtggc atcattcctg atgctgaccc agatatttta atttttttct
    49681 ttaaaaactt acaaacatac ccagcaaaga aacctgctat tactgctcct aagaatcctg
    49741 cattagtatt acttgctatg agcccaccaa taaaacctgc acccatagct ggtttctcac
    49801 ctattgaaaa tgctataaat cctgctaata ccgtatttaa tagacctatg ccagtccaac
    49861 caacttgttc cattaagtaa agaatatgat aaaaaccaga tacattttta taagcatcta
    49921 aacttgttat acccactgct aaagctgtaa gctttgggat agctacaact aaagatgagc
    49981 ctattacaag tggcaacata tatgagatac ctgtcattaa gtgtccctta agttcactta
    50041 aaagagattt atttttttta ctcattttta atcctcctat ataagtttgt tatatttttt
    50101 gataatatgt tataattaca ttagacaatt ttttaatttt tgatttttct cattctatat
    50161 tagagtgaga tttttttatt aagaaatagc ttctatacac tttgttaaga cagcttctgg
    50221 tttttttaac gctataccta ttttgacttt tatcactttt ttaccatcaa atctttccat
    50281 tccagatata gtttggtcag atgctataag tataaagtcc gcatcttgtg cttcttcttt
    50341 tgttatagta tttactcgtc ccatagcacc ttgttgttct actttgattt catgacccat
    50401 ttttgatgca gcttgttcta aagcttttgc tgccataggt gtgtgtgcta atcctgctat
    50461 acatgatgtt atagctacta ttttcataat tattcctcct tcattttatt agttatatat
    50521 tttactaaat gacttgcatc actagcattt ttaacttcac ttgtaaaatc atcctccatt
    50581 aaacatgtgg ctaatttaga tagagttttc aaatgtatat ttccttcatt tttatgtggg
    50641 gctaacaaac taaatacata tctaacctta ctatcatcta aagttttcca ttctaactcg
    50701 ttagttgttt taatatagag tatggaagct tcctttacat ttacactctt tgtatgaggt
    50761 atcgcaaatc catcttttat tcctgttgga aattcatttt ctctttttag aaggtctttt
    50821 aaaagagcct ctttattagt tgtaatacct agtatataag cactatctgc aataaaattt
    50881 aatacttctt ctttgctttt taagtcttta tctataaata tatatttttc ttgtagtacc
    50941 atatattttt ccactccatt cataatgtct taacttatat ttatattgta atcattatcc
    51001 taattaaatt aaatataact aatttccact tcgacatgga aatttatatt atgataataa
    51061 ctaatttcca tatagaagtg gaaataaatt attataatac aattttatta gagtaattgt
    51121 attatatgag tgtaaatagt ataatttaga agaaattcta taagggggga tatttatgca
    51181 caagagattg ctcacgttgt ttaaattatt aaatgaaagt gatgataaaa ttacttgtaa
    51241 aactttaagt aatcatttaa aagtgagtga gagaactata agaaatgata ttacttctat
    51301 aaatggaact ttagagaaaa atggtgctat tattaaaata aaaaaaggag aaggatatta
    51361 tatagatatt cttaatttag cattatacca acagtatcta gcattaatat ctgatgatat
    51421 tatggattca agtgaaatac cagattctcc tatagaaaga aatcaatata ttttaaaata
    51481 tattctctat aacaatacat atataaaact agaagattta gctaatagct tgtatgtgag
    51541 taaatttaca atactaaatg acataaaaag aataaagcct attttgtcaa agtataattt
    51601 aatattagtt tctaagccat attatggagt taaagttgaa ggtaaggaaa tagatattcg
    51661 aagatgtatt tctaataata tgataaatag gaattttgaa aactatataa ttggaattac
    51721 agatagagaa atagaattat ttaataatgt agatttaata gagcttcaaa gggtagtgtt
    51781 aagtgaaatt aataaattta atatcaattt cctagatttt aatctaaaaa actttattat
    51841 ccatttagct attactgtaa gtagaatact tgatggttac tgcttagata atgttttaga
    51901 tgttgtttta acagattttc aatcgaatac aactgttgaa aatatattta attatattga
    51961 gagtaaatat actataatta tttcaaaggc agacagagtt tatctatata atcattttat
    52021 aactaaaagt tctcttttgg ataacgtttc caatagggta gatactaaaa ttatagagta
    52081 tgttgaagaa attttagaag taatcaacaa tcaatatact tttgacctta gaaatgatag
    52141 tgtattattt gatgatttag tactgcactt taaatcaatt ctcaattcta aatcttataa
    52201 tttaaataag gtgaatcccc ttataaatac aataaagagt aattatcctt tagcatttga
    52261 aataacttta aatgctatag aaaaagtttt taaaaatagt atttactctt taacagaaga
    52321 tgaaattgga tatgtatccc tgcatatagg tgctggaata gagagatttt ttcaaagtaa
    52381 tattaagtgt aaaaacgtag tattagtatg tggttcaggg tatggttcaa gtaggttatt
    52441 agaggttcaa ttaaacaaag tttttcatga taaaataaat atacttcaat gtctatcatt
    52501 taatcaattt ttagctagtg aattgtcaga tgtagatata ataatatcga caattccttt
    52561 aaatcatgat agtattccta ttgtattagt ggatttaaaa ctattaaaaa aagatataga
    52621 gaatatatct aagtcaatca ctaataattc ccatatttat agtaatcttt tggacaattt
    52681 ctttgataaa aatttattta ttgttaatcc taaaatcaaa gataaagatg agcttataaa
    52741 gttgatgtgc aacaaattaa ctcaaagtga aattgtattt ccatcatttg ctgaatctgt
    52801 attttacaga gaaagtttat cttctaccaa tatagatgat tttttagcta tacctcatcc
    52861 tatggaatta agctctataa gaactaagat ttgtatttcc atattgaatg aaccaatata
    52921 ttggagtgaa aattctactg ttaaattaat catgatgttg gctataaata aagatgatta
    52981 tataaaaata aactccattt atgatatcct tttaaagata attcatgaca atgatattag
    53041 agatagtata tctaattgta atgattttga taattttctt tccataatca agtctatagt
    53101 atagattttt atattacata agttttaaaa actttaataa aatatttttt gtttttagca
    53161 taaatagtat aagtaagttt tgtataattt gttattattt tgtattgatt ataattatta
    53221 tacaataaag attctgtctc aaaatagaga gagaaacctg tttttcattg ataaaatgat
    53281 aaaaatatat ctgatttcat acaaaaaaga gtgtctcatg aactaaaaag ttcattttga
    53341 gacaccacct ttattatttt atattattta tctcttgtat atattactat agcatccctt
    53401 aaaaacttag ctaatccagg ttgttctcta tcataatatg atgtaaaacg ttcatcatat
    53461 acatacatct gtgctagaga ggaatgagct tctttagagt atgtgttcca agtgtaacac
    53521 aaccatttat gatgtaattt tgcaacttcc tgagccagtt cactagaggc atcaccagtt
    53581 ttaaaagctt ttttaagttt actaattatt tcgatattta ggttttgcca attttcataa
    53641 tcttgcttag acatattttt aagtttttta tttgatgtat ctataatatc tttaccatat
    53701 ttctctctaa tttcagttcc ataatttttt tcattttcat caatcatctt ttctttaaaa
    53761 ccttcaaatt tttctatatc tgtcatagtg tattttccct ccttcagagc tatagtttta
    53821 gttacatttt ctattagtaa atcaatttgc tttcttttgg ctagtaattt attatggtgt
    53881 tcttttaacg cacttaaact atcgaagttt ggtgaattta taatgttttt tatattttct
    53941 aagttaattc ctaattctct ataaaaaagt atttgttgaa gtttattaac ttcattttga
    54001 ccatatatac gataacctga agaatttatt ttaagtggct taagaagacc tatttcatca
    54061 taatatctaa gtgttctagt acttatacca gctagtttac ttaatttttg aactgtatat
    54121 tccataagta gtacctccta taaattaaat atacactttt acgcaacgta aatgtcaata
    54181 cattaaaata taaaaattta tatcttttaa taaaaatata aaaaaatatc tttactggat
    54241 attttacaca caactgtcaa tactcactag tgaaaattaa aaaataaaat ttatagacta
    54301 tctttactaa aaaatagaag gtctatagtc taggaggaac tgtatgaatt taaaaagaag
    54361 caatgaaaaa cgagaagagt acagaagaat gtattcagat aaagaaagtt ttttaagttt
    54421 gattcaaaat tttacaagtg tctcaatagc aaaagtatta actcttaaaa atatagagtt
    54481 agaaacatct tttatatgtg aatataaagg aaaagaagtt gatataattt ataaggtatt
    54541 ttctaaaagc ggcaaagtat cacattatat agtgttagaa tttcaaacag aaatggatac
    54601 tgaaattgtc ccaagattga aatcgtatag agaacaaatt tggaaaagtt ttattatgaa
    54661 aaaaagcctt gaagaaatag aagataaaaa ttttaaactt cctaaagtta taccagttgt
    54721 tttatatagt ggacctgaaa ggttaagtag aaaaaaagga attttggata ttgtagaatc
    54781 tatatcggag ttcagtaata attctagtat gaaaaattaa aattacataa tgtgtttatt
    54841 ggtctaaaat ggaaaactgt cgcataaact tgaatatgaa aatatttata gatacaggtt
    54901 ctatgtggag gtgttccatg agaaataaca agtctaaggt attgctagga atactttgtc
    54961 tagcaacagg aatggctgta attctgtcaa tgttgcttcc tggctggatt tggtcagcac
    55021 ttaccgcatt aatacttatt ggatgtggag cattattatt tttttgttaa aatagtttta
    55081 actataaagt gtggggtgag tattgatgaa agtagtaaca ataaaattac caaaatggat
    55141 ttcaagtata atcctaaaat ttatgagaaa gagtaaaaat gattaaatta aaaagcctac
    55201 ttacggaagt aggcttttaa acgtggttac taagctcttt caattttacc agaacgtaaa
    55261 catctagtac aaacttttac tctcttagga gctccatcta taatcgctct tacgcttctt
    55321 aagttagctg accatgttct tttattatgt ttatttgagt gtgatacttg gtttccagaa
    55381 accttacctt taccacatac gctacatact tttgccatct acgcacacct ccttaaaatg
    55441 ataactattt aaagactaaa aacatattta tattatcata aataacaaaa atttgcaata
    55501 gaaatatata tttgccttac acatattgaa gaatttctta ttatcatata aaattatata
    55561 tataatttta tataaagtaa atatatttgg aaaataatta ttatttttct ttgaatatat
    55621 atactataga agaaatttta tccaaaaact tttctaggtt taaattatac catatttata
    55681 gtatgatatg attataattt tatataataa ataagtaaaa atagtaaaaa ataaattaag
    55741 aaatgttttt aataaaaata agcttaaggg ggtcaaccat gagtgcaaag gtaacgaatc
    55801 aatatggaaa tatagaaata gataatcaag taatagctca agtcgtatat agagctgcaa
    55861 tggaaagtta tggcttagta ggtttagcat ataagtctaa aggaatagta gagctattaa
    55921 aaggcgagaa cgcaactaaa ggtgtaagag ttgaggaagt agaagaagat gccatagcaa
    55981 tcgaacttta tgttataata caatatggta caaatatatc tactgttgcc aataatataa
    56041 tagatagagt aaaatatgta gttgaaaaaa tgactggcgt aagagttact agaattgata
    56101 ttaatgtaca aggaataaga gttaagtaat ttcataggag gaaacaaatg attcaatata
    56161 tagatggtaa aaggttaagg gagatgttta tttcaggtgc aaacaatctc caaaacaata
    56221 aagagttagt tgacaagtta aatgtattcc ctgtaccaga tggagataca ggaactaata
    56281 tgtcattaac aatatcttat gccttaaaag aattagcaaa agttgaaaat gataatatat
    56341 cagatatcgg aaaagcatta tctaaaggtt ctttaatggg agctagagga aactcaggag
    56401 ttatactttc acaaataatc agaggtatag ctaaatctat agaaggaaaa agtaaattat
    56461 caacagaaga tttagcaaaa gcttttaaaa atggttcaga cacagcatat aaagctgtaa
    56521 taaaaccaat tgaaggaact atacttactg tagttagaga aagtggagag tttgcaataa
    56581 aaactgcgaa aaaagagaaa gatgtagtaa agtttttaag tatgcttgtg aaggaatcaa
    56641 attcttcatt agaaagaact ccagaccttc taaagaatct aaaagaagct ggtgtggttg
    56701 actctggtgg aaagggtctt gtacttatat atgaaggaat gttagcttct ataaaaggcg
    56761 ataacataga aataaaaaat gttgacctag atactaatat ttcaacaagt atggattttg
    56821 caaagagtac tactagcaca gatgatataa aatattgcta ttgtacagaa tttattttag
    56881 aaagttctaa ggtagaagat actaaaataa gagacataat gatggcttat ggtgatagcc
    56941 tagcagtagt tggagatgat ggagtcataa aggtacatgt acacactaat gacccaggaa
    57001 atgtacttca agaagctcta aagtacggtc aattattaac tataaaaata gaaaatatga
    57061 agttacaaca tgaaaataca ttactggatg tagaagaaaa gaaagaaaat gatagtgaac
    57121 ctttagaaga agaaaaagag tttgggttta tagctacttc tatgggtgaa ggtttggcaa
    57181 atatatttaa agatttcgga gttgaccata taatagaagg tggtcaaact atgaatccaa
    57241 gtactgaaga ttttatgaat gctataaagc atataaatgc taaaaatata tttattttcc
    57301 caaataacag caatataata atggctgcta atcaggcaaa agaattgagt gataaaaata
    57361 taatagttat acctacaaaa aatacgcctc aaggatttgc tgcattagta acttttaatg
    57421 gagaattaag cgaagatgaa aataaagaag ctatgatgaa tgctttaaac tcagttaaat
    57481 caggtcaagt aacttttgct gttagggata cagtgatgaa tgaaattgat gttaaagaag
    57541 gtaatataat tggaattgca gaaggaaatt tattatcagc aggagattat gtggatgaag
    57601 taacatcaaa ccttattgaa aagttggttg atgaagatac tgctataata acattattct
    57661 ttggtgaaga tgttacagaa tctcaagcaa atgaactacg tacttcttta gaagaaaagt
    57721 ttgaagatgt agatgtagag ttatattatg gaggacaacc tctttattat tacttaattt
    57781 cagttgaata atgattataa gaacctgtat gaccaagtag cttttataaa attggttgta
    57841 caggattttt gtgtagtagg tgatatattt gttggattta tataaagatg ttcaatatgt
    57901 taagggaata ggacctaaaa aagcagataa attaaataaa ctgggtatat ttacactaaa
    57961 agacctattg tattattttc caagacaatt tgaagataga aataatctaa agaaaatagc
    58021 acaattagaa gatggtgaga aagttacgat aaaagcagta atatcaagta taaatacatt
    58081 tagcccaaaa gaaggtatga ctttaacaaa gattgatgta aaagatgaga caggctcggc
    58141 taaattagtg ttttttaata agagttatat aaaaaatact tttcgtccag gagattcaat
    58201 attagttttt gggaaggtta agaaaaaatt taataactta gaacttacat catgtgaatt
    58261 agaatatctt actaattcac ctaagaatac atgtagattt atgcctgtgt accagcttac
    58321 atacggtgtt acaaataaag aaattatgag tataattaga acagtacttg aagataaaga
    58381 attaattata caagaatata tgccacaaag aattatagaa aaatataggc tatgtagtat
    58441 agattttgca gttagaaaca tacattcacc aagtagtaag gaatcattaa aaatagcttt
    58501 atatagaatt gtatttgaag aattacttat actacaacta gggttgtttg tatttaaaag
    58561 tggcagaaat aaagaagatg gaataaagtt tgaaacaagt aaagacttaa aaaaaataat
    58621 aagtgcttta ccatttaaac tgactaaagc tcaaaacagg gcattagatg aaattataca
    58681 agatatgaat ttagagaaaa taatgaatag attggtacaa ggtgatgtag ggagtggtaa
    58741 aacagtagta gctctcttag cacttgcaaa ttgtgtttta aatggttatc agggcgcttt
    58801 gatggcacct acagagatat tagcagggca acattatatt tcacttactg agtctctaaa
    58861 agattttgga ataaatgtag gtctattaat aggtagtctt acaaaaaaac aaaaggatac
    58921 agtattggaa caaataaaga ataatgagat tgatatatta ataggtacac atgcactaat
    58981 tgaagataag gttgaattta ataatattgg tttagttata acagatgaac aacatagatt
    59041 tggtgttatg caaaggagca aactttcatt gaaaggagca aatcctgata tattagtaat
    59101 gacagcaaca ccaataccaa gaactttagc acttatactc tatggagatt tagatatttc
    59161 tattatagat gaacttcctc caggaagaca gccaatagaa acaattgcta ttgaaaaaag
    59221 taagcgagat agagcatata ataatcttgt aagaagagag gttgaatcag gaagacaagt
    59281 gtacattgta tgtcccttgg tagaagaaag tgaagccata gaagccaaat cagcagttga
    59341 acttgttgag gagttaagag cggaatattt tcacgactta aggcttgggt tgcttcatgg
    59401 taaaatgaag tcaagtgaaa aagatgaagt aatgagactt tttaaagata aagaaataga
    59461 tattttagtt tcaacaacag taatagaagt tggtgtcaat gtgccaaatg caacattaat
    59521 gataatagaa aatgcagaaa gatttggact tgcacaatta catcagctta gagggcgagt
    59581 tggaagaggt agtcataaat cgtattgtgt actaatttat gattctaaaa cagatgtatg
    59641 tagacaaaga atggctataa tggaagagac caatgatggt tttaagattt cagagaagga
    59701 tttagaaata agaggacctg gggaattttt tgggacaagg cagcatggtc ttccagaact
    59761 taaggtagca aacttattta agcatataaa aatactgaag ttagcacagc aagaagctcg
    59821 atatatattg ggtgaagata ataatctaca attaaaagaa aacatggcac tcaaaaaaga
    59881 aattatagat aaatttaaag atacattgaa agaaatttca ttaaattaat tttaaattgt
    59941 gttaaaatat tactaatgta ataatgtgct gaagggagat tgtcatattg agagtaattt
    60001 caggaaaagc gagaggatta aaactaaata ctccaaaaaa tgaagatgta aggccaacta
    60061 cagatagagt aaaagagtct ctatttaata tgataaattc atatataatg gaaagtgaag
    60121 ttctggattt atttgctggg actggttctt taggaataga gtgcttatct aggggtgcca
    60181 agtcatgtac ttttgtagat attagtaagg aaagcataga tattgttaag tccaatataa
    60241 aaaaggcaag agttgaaagt gaaagtatta ttttaaacct tgattttaag actgcaatag
    60301 ataaacttaa attacaaaat agtaaatttg acataatttt tatggaccct ccgtattata
    60361 aaaatatgtt tatagaagct attgaaaaaa ttgataattc taatctattg aacgaagatg
    60421 gaataatagt tgtagaacat gatacgaatg atttatttcc agataagata tgtaaattgg
    60481 agaaaactag agataagaaa tatggaaata ctacattaac tttttataag atggaggcat
    60541 aatatggaaa ataaacctag aaaagctata tttgcaggaa gttttgaccc aattactaat
    60601 ggacatttag atattatttg cagggcttcg aagttatttg acgaattaca aataggagta
    60661 ttaaataatc ctaataaaaa gggtctattt agctttgatg aaagagtaaa acttatagaa
    60721 aaaagtacaa gccatttaaa taatataaaa gttgtgactt ttgatggttt attaataaat
    60781 tactgtcagg aaaatgggat tggagcatta gttagaggtg tgagaagtgg tgctgatgtt
    60841 gattatgaac ttcagatggc acatatgaat agagagctta atccagatat agagactata
    60901 attttaccaa gttgtacaaa atattcattt ataagttcat ctttaataaa agaggttttg
    60961 ctctttgatg ctgatataaa aaatttggtt ccaaagattg ttttggaaga attaaagaaa
    61021 aaaactagtg ggggtaattg atatatgaag atagatttag aaatgattga actatttgag
    61081 cagttagagg agatatttag aagtgcttct acaatccctt tctcacataa atgcacagtg
    61141 gataaagatg aggttttagc aataattaat gatataagaa ctttaatacc agaagaagta
    61201 acacaggcag tatggattaa taaagaaaga aataaaataa taagtcaagc taagcaagat
    61261 gctacaaata tagttgaaca agcgaaaaaa gaagctgaga gaatacaaca agaatatcaa
    61321 gataatatag aggaattaaa gaaaaattct gaagatgtag taaaggcata tgtagaatcc
    61381 agtgaacctg ttgttcaagc agaccaaaga gcaaaagata tagttgatag agctgagaga
    61441 atagccaatg agataagaat tgggtcaatt gaatatgcag aggatgtgct ttctagtgtt
    61501 gagtataatt taagagaaat attagaagaa gtaaaaagag ataaagctga acttagacct
    61561 aaaaaataaa ttttaaataa ataaaaatgg agctatcaca caaaaaattc caatttatgt
    61621 gtgatagctc tcttttaata tagcaatttt ttgttatata attgtgcttt ttagattact
    61681 tatatcttat tttgatatta taatgtagtt taatctttta tttgttgaaa tcaacttatt
    61741 tatttgtata aataatatag gttattttca aattttttta ataattttac cactgtcttc
    61801 ttttagatta gagttagact gtgcaaaatt ataaaataat actaaatcat gtgcaattat
    61861 ttggtatggc actacatgta gaaaatatag ataataaaat taaggaggta gtatgaagga
    61921 aagggctaaa aaaatattag attttattat taaaaataac aatgtaacat cacaagaact
    61981 acaagaaaag tttaatgttt caaagagaac tatttattac gatattctag ctataaatga
    62041 acaactagga aaaagtggta atataaaaaa tgtaaaacac aaatttatat ttgaaggtaa
    62101 tttatgtgat gcaaggaaaa taatttcaac tgaagaagat aaatttttag atagtgatta
    62161 cagaaaaact tttatattaa acaagatatt acttggcgaa aaaatatcaa tagaaaaact
    62221 aacaaatgaa atgttacttt caaaaaacac agtagtacaa acaataactg atgtaaaaaa
    62281 ataccttcaa acaatggggt taagattaga gtataaggga aagtacaaaa ttataggtga
    62341 tgaatacgtt attagagagc tgtttctgat aattgttcaa gaaaatatat tggaaattaa
    62401 ttctataagt gaggaagtaa gtagtttcga tacaaaagga catataaaac ttactgatta
    62461 ttctttatta aatctaacta agtttgtgga atttctaaat aaaaggataa gagatgggaa
    62521 aacattatac tcatataaat atctaaatga agctaaaaaa attagttact ttagtaattg
    62581 taaagaactt ttatgtgaag aagctaatga aaatgaacaa gcctatatat gcacttacat
    62641 aagttcactt cccagcttaa atagtgaagt taaggaagat gttgttgaag aatatgtaga
    62701 taaacttata gataagtttg aagtaaatac agcaataaaa ttagaaagta agcatgagtt
    62761 taagaaaaat attttaaggc acctccattc ttcttacaac agaatacgat ttaagtttcc
    62821 tattagaaat ccaatgttag atgagactaa gtataaacat gagtcacttt ataaaattat
    62881 aaaatcaatt atagaaaatg aagaagagtt tcctgtattt gaggggataa gagaagaaga
    62941 aataggattt atagcagcgt attttggagg atatttaaga gggtctaggg ataatggtct
    63001 aagaagaaat aaagtcttac tagtttgtcc taatggtctt atggtatcaa agagtttgga
    63061 aatacaacta tataaataca taccaaccat agaaatagta ggtatagtat ccattaagca
    63121 actaaaagaa gtaaatgtat actacgatta cataattaca actatagata tacaaaatgt
    63181 aaacaacgta attgttgtaa atcctctttt aacatcatca gatgttcaat tacttatgaa
    63241 caaactaata agtgtaaaag aaaacgagaa gtatttcaat cttgaattaa taatacaagc
    63301 tataagaaaa aatggagtta tcaataatga agaagcacta aaagctgatt tattaaacat
    63361 aatacacaag atagatgaag gagagatgta tcaaccaatg ttaaaggaat taattaatgc
    63421 agaaagggtc aatataataa aaagtgttag agattggaaa gaagcaataa aaatagcctc
    63481 aaagccattg ttagaagata actctataga agagttatat atagaaaata tgataaagtc
    63541 agttgagaaa tatggaccat atattgtttt agctgataga tttgctctac cacatgcaag
    63601 ttctaaagaa ggagtaaaca agcttgctat gtctttacta atagtagaag atgaagttga
    63661 tttattagga aaaccagtaa atatatttat ggtattagct gctgtagata acactactca
    63721 cattagagca ttagcatcac tatcagagat gatgtacgag gaagaaaatg taaaactaat
    63781 aattaatggt gataaaagtt caatactaga acttataaat aagcaaaatt aggaggaatg
    63841 aaaaatgaag atattagcag tatgtggttt tggtgtaggt tcatcaatgg tattaaaaat
    63901 gacaatacaa aaggctctaa agcagttagg tatagaatgt gaagtagaaa atacagatat
    63961 aaattcagct agaggtgctg attgtgactg tatattcaca agtcaagaat tgttaaatga
    64021 attaaaagga acttgtaatg tagatgtata tccagttaaa aagtacatgg atttagcaga
    64081 agtcacagaa gttgttcaaa cttttttaag tgataaaaat gataagaaat agtataagtt
    64141 ttaaaaagta aatttaagtt aatcagaata aaataaaaac ttactaaatt caaaaatagt
    64201 aagaaagaga ggagggattt agtggtagaa aacttaaaca gttgacctat cactaaaaaa
    64261 tataatgctt gattttattt caaataatat tttacgtaat ccatctatgt taattggatt
    64321 aatagcagca tttggtcttg tactacagaa gaagaaagca tctgatgtta taaaggggtc
    64381 actacttgca gctttcggaa ttataattat ggagactgga acaggtatgt tagttagttc
    64441 aatagcacca attaatggag ctttccaaag tataagtggt ggtgcagtaa caaaaggttt
    64501 aagtgatgtt acttttactg caagttatgg tggaattata ggtttagcaa tgtttgcggg
    64561 tttagctatt cacctaatga tagcaagatt tactcctatt aagacaatct ttttaacagg
    64621 tcacatgctt tattggttcc cattcatatt tgtagcttca ggagttgaag ctggattaaa
    64681 tggtggagta ttaatagctt ttgcagcagt attatcagca ctctattggt caataatgcc
    64741 ttggttatta agaaaatatg tgtttgatgt tataggagat gattctttta cattaggtca
    64801 tccatctggt tgtttagcac ttatatcagg atttgttgct aaattagtag gaaataaaga
    64861 aaaatctaca gaagatataa acatacctca aagtttatca ttttttagag aaatatctat
    64921 aagtggtgga atggcagtgt ttttaatgtt tatagttgtt gggatagtaa taccaggtgc
    64981 gtttaaagat agtaatgagt ttattggaac gtatgcaata aagcaaggtc tttcttttgg
    65041 agcaggtctt ataataatgc ttcatggggt aagaatgcta ataaatcaaa taatgccagc
    65101 atttcaaggt atatctgaaa aagttgtgcc aaatgcacta cctgcttttg actgtccaat
    65161 attatttaat tataaaccaa atgctgtatt aatgggattc ttagttgcta tgctaacatc
    65221 tacagctatg attttaatat gtaactactt taatgtattt aatttgctac ttataccact
    65281 tgttataact tcattctttg agtgtggagc agcagcagta ataggagaat cacaaggtgg
    65341 tatacgtgga gctataatag gtacagctat agctgcaata tttatggtag ttttagtagg
    65401 aatatctgct gtaatttact caggaactat tcaaaattgg atactaatat ttggaggtaa
    65461 tgacctttca ttatttggta taatcagtag gtttataggt tcactatttg gaggaatatt
    65521 atagatatga aatttaaata catagatgag ataagaagat taattgatat aatagaaaac
    65581 gaagaaaaag tcaatatgga aaaagcagta caaatctttg ttgaagcaat agaaagtaaa
    65641 aatgctatat tttcatttgg agcttcacat gcaggaatat taacagaaga attattctat
    65701 agagcaggtg gctgtgttct tataaatcca gtatttgcaa aatctctaat gttagataca
    65761 gcgcctataa ctcacacaag taagatggaa agattagaag gatatggtac agctctagct
    65821 gataaaactc caattaaaaa aggagatgta gttatagttc attcagtatc tggtagaaat
    65881 ccagtaagta tagagtttgc tatgaaagct aaggaaaata aggcaatagt aatatgtata
    65941 actaatttaa gttactcaaa aagtgtatct tcaagacatt cttcaggaaa aaaactttat
    66001 gaagtatgcg atttagtgat agataatcat ggtcaaaagg gagatgcctg tgtagagata
    66061 gatggattaa accaaaaagt tagtccaact tctactgtaa tagcaactac tgtgatgaac
    66121 tctattatag ctcaagctac tcaggaatta gttaataaag ggctaaagaa tcctccgatt
    66181 ttctatagtg caaatattga tggtggagat gagttaaata agaagatttt tgatgaatat
    66241 aaaagtgtaa ttcattatga atattaaggt taaaaaaata tgttaatgaa ctttgaagtt
    66301 tatcaacaaa gaatattaat aatatataat aaatgctatc atttaaaagc tgtaggtaaa
    66361 aatctacagc tttttattat tgtagattaa aaagatgcgt aattaaattt taaattggag
    66421 aaaataaatt ggaaggtatc aattataaat attagaaacg ttgtcataga aaaaaactat
    66481 attaaaaaaa agtacataga aaaaactgat tagacaataa atacatgctt tgataatatt
    66541 ttaaatggag tgaaaatgtg tagaattata atgaaaaaag aaaataaaaa tgaaaaaaga
    66601 aaataaaatg gagggaataa aagtgggtat gttaaaaaaa ttatgttcac tagctatggt
    66661 agcaattatg actacaacac ttataacagg gtgttcaagt ggaaatggaa aagattcaaa
    66721 aaaggatggc gaaaaagaaa aactagttct ttggatgcca ccagtagaaa ataatatgaa
    66781 ggaagtttgg gaccctattt tagataaatt tgaggaaaaa aataactgtg aagtagattt
    66841 acagataatt ccttgggata attattctga aaaatttgca acagctataa gtgctggcga
    66901 aggtccagat gtaggatata tgtatgcaga aatgtatcca cagtttatag aaagtggagc
    66961 agtagaagat ttgactaact atgcaactaa agaggataaa gagcaatcta tttatataaa
    67021 aacatctgaa atgatgggtg gaatgtatgg tatgccattc caagcagcaa atccaggggt
    67081 attatactat aacaaggata ttttagagaa actaggagaa aaacctccta aaacatggga
    67141 agattttaaa agaatttgta aaaaagcaac gcaagatact gatggtgatg gaaagataga
    67201 ccaatgggga ttagctcagg gatggggagc taaaactttt ggtaacttaa actggaactg
    67261 gtatccttat ttatggcaag ctggtggaga tatatttaat gatgatttaa aatcggttaa
    67321 atttaatgat aagagtggtt tagaagcagc taagttctta aaagaattac aagcatatgt
    67381 gcctgaagat tctttatcta aagatagtaa tgaaatgata gaaagtgtat ttggaccagg
    67441 gaaagcagca tttacaataa tgttatcttc tgctgcaaca agtgtatttg atgaatcatt
    67501 cccggattta aattggggat ttgtaactgg actagaagat aagaaagcag caacttttgg
    67561 agcagtagac catttatctt taatctcatc tgcgaaaaat aaagaacttg catacaagtt
    67621 aatacaacat atgttaagtg ttgaatcaat gacagaattt cataaagcaa taccaagagc
    67681 accaataaca aaaggtgaac catatcaagg tgatgaaaga ttcaaagaaa tggtggaaaa
    67741 tgacaaaaat gtatatagac cattagtagt aggacctcat ggagttgaaa tatatgaata
    67801 tttatggaaa gaacttcaaa ctatgatttc aggagataaa actccaaaac aagcgttaga
    67861 tgatgctgca aaatattcaa atgatttatt agcacaataa aagtttaaag ctgtaatatg
    67921 ttgtaaagta ctttacagat taaaattagc attgtattta taaatacaat gctaatattt
    67981 atattggaga ggataaaatg gaaaacttag ttagagagtt tgaagaaaat tcaaaaagaa
    68041 aaaaaacaaa attaaatatt aaaccatata tgtatatatt gccattggga ataattttag
    68101 tggcgtttta tgtgatacca ataataatgt caatatactt tagttttaca aagtataata
    68161 ttattagtcc agctactttt ataggtttag aaaattataa aaaattattt acagatgaaa
    68221 cattaaaagt atctattata aatactatta aatttactgt tgttgtagta ccttgccaaa
    68281 ctatattatc attgattttg gctgtttgga ttacaggaaa aggaaatagt aaaatagctt
    68341 catttgctaa aggtgctata tttataccag tattatcatc tatggttttg ataggtatgg
    68401 tatggagggc tttattgaat ggagaaggtt ctattatata tcaggtatta ggtgcctttg
    68461 gaatagaatc atctaaactt ttaggagata gtaagacagc attacctaca cttatgttta
    68521 tatctatgtg gaaaaatata gggtatttca tggtaattta tatttcagct ataatgaatt
    68581 taccaaaaca ctgctatgaa gtagcgaagg ttgatggggc tacaaaactt caagaattta
    68641 taaaaataac tgtaccttta ttgaaaccaa ctacaataat ggttgtattt ttagggtcga
    68701 tatggtcatt acaagtattt gacttaattt atactgtgac aggtggaggt ccaggtatat
    68761 ctactatgag tatagttatg catgcattta acttaaactt taaaaacttt aattctggat
    68821 atgcaatgac tgtagcaaac gtattatttt tgttaatagc agtagtttcg attttacaaa
    68881 ataagcttgt aaaacgagac aattcagatt tttagaaagg taggtataat atgaaaacag
    68941 caagaagatt attaagtgat ggtttacttt tatttatagc gtgtgcaagt ttggtacctt
    69001 ttatatacat gttgataata tcattgaaga taacatataa ctcatatagt ttggatatat
    69061 ctttttcaac agtaaccctt caaaactata tagatatttt tactaaaaaa ggatttgcac
    69121 aatatttttt taatacagca atagtatctt tttcaggtgt attattaaat ttagtattta
    69181 gtacattagc aggatattct tttgcgaaga tggattttaa aggtagtgat aagttatttt
    69241 tatttatgat aatgacttta attatacctt cccaagttac aatgatacca ctatatataa
    69301 taatgaaaca cttaggatgg ataaatagtt atcttgcact tattatgcca ataccaactg
    69361 catttggcgt atttataatg agacaagcta ttttaggagt accaaaagag ttattagaat
    69421 cagcaaagat agatggttgt tcggatttta gaattttaat acaaatagtg ttgcctttaa
    69481 ttaaaccagc attaattaca ctagcaatat ttacttttat gggagcatgg aacgagttta
    69541 tgtggcctct tatagctaca actaaagatg caatgagaac attaacagtt ggattatcta
    69601 ctcttaagac attccagata actaattatg gacagatgat ggcaggggct acaataacat
    69661 ttttacctcc atttattttc tatttgattt tacagagtaa atttgttgaa ggtgtgtctt
    69721 tgtctggtat aaaaggttaa atagtctaat ttaataatat ataaagaaac ttatataaat
    69781 atggaggaat ttaaactatg gaaatttcat atgtactgaa agattgcaca ttcaaacaca
    69841 ataaatactc agttgtagaa gctgaaactt ggaaagataa ggatttggat attgtagtag
    69901 ctaaaggtga aaaatttgca tttcaaatta tgttaaaagc aacagaagaa tttaattgta
    69961 caattgataa aagtagtgct atatcatgga aaggcctggg aaatagagta aggttagcat
    70021 taaatatgcc taatagttta gaaaataatt ttagtataaa tatattagga tatgttcaag
    70081 atgatacaaa ggcatttgtg aatgatgcta ttttaaggga taaagatgtg ttagtagagc
    70141 aatatttgcc tcaaacattt tggattgaag gtcaagtacc agaagatttt gaagaaaata
    70201 accttgatat aggtattgat atatttaaaa gctttggata tgaagatgaa gaaaaagttt
    70261 gtacaattga tgttcctgta aaagtaagaa atgttgtgct aaagccttta gatgaaagca
    70321 agttcttttt agatttatgg caacatccaa gctgtttagc tagaatgtat aaagttgagt
    70381 tatggtctga tatacatttt gaaatagtcg ataactattt aaaagaatta gcatctttag
    70441 gagaaaaagt tgcaacagtt atagtttcag attatccatg ggcagggcaa agttgttata
    70501 aagtttataa aaatccatca aacttatatg aatataacat ggtaagtgta tcaaaaggat
    70561 tggatggaaa gattaaatgt aactttgaga gtatggatag gtatataggc atagctgata
    70621 agtataaaat ggctaaggag atagatttat ttggtctatt aggtaattgg tgtgctggtg
    70681 agtttggaaa tcctgtagaa ggttataagg accctataag agtaagatat tttgatgaaa
    70741 aggataaagt atttaaattt ataaacaata caaatgattt aaaagaatat ataggattag
    70801 tattaaatca tttaatagag tgtggattat gggacagagt aaggattata gctgatgaac
    70861 caaataatcc agaagtagtc aaagagtgta tagaatttat aaattctact gtaggtactc
    70921 atcaagttaa atataaatca gcaactcacg accaaaactt tttagacaga gctaaagatg
    70981 aaattgatga tatgtcaata aatttaaaac ttactataca aaattataaa gatatagaaa
    71041 gtcttaagaa aaaaatcaat gacaagggtg ggatattgac ttggtttgta tgctgttttc
    71101 cagaaaaacc aaatagtttt ttaagttctc cttttgtaga aaatagaata ataggatggt
    71161 atacttatta ctttggtctt gatggatttt taagatggga ctataattta tggacagaag
    71221 acccttggaa agattcaagt tacaaattcc ctatttggaa agctggagat atgttctttg
    71281 tttatcctgg aaaagattta aagccagtta gaagtgtcag aatggagaat ttaagatttg
    71341 gaatacagga ttttgagtta tttacaatgt tagaaaaaga aaaggtaaga gagtatatag
    71401 aagttgagct tatgcaagaa ttattaaata aaaaagaaaa tgctgaaatt aaaggttttg
    71461 gtgacataga actaggatat tcacttgata attggagata tgataaagtt aaaaaatatg
    71521 tattagagtt gttagacaga gtataaaaaa tataagagtg tctcaaaatg aactttttag
    71581 ttcatgaggc actctttttg tatgaaatca atatagtttc attgtttcaa caatgaaaaa
    71641 taggattatt tctattctaa gacagccctt tagtttttta gttgtattca atgttttaaa
    71701 actaactata aacgctataa agtttataaa tgacaataat tatatataac atgatgtact
    71761 ttaatttgct ataataggga ttgaataata ttatatggaa gataacattg tttgggggga
    71821 ttaatataaa aagaataggt attattataa tgtttttttt aagtatatct tttattggat
    71881 tttatcttgt aataagagat aacagtgata cagttaagat gcaacgaggg ataaatatag
    71941 gtaatgcact agaatcacct aaggattttc cgtgggatgt aaaaatgtca aataagtttt
    72001 ttgatgatat aaaagatgca ggttttgaca cagtacgtat accagtaagg ttttctgatt
    72061 atacgtcaga ttctgataat tttaaaattg atgaagaatt ttttaaaaag attgataaat
    72121 atgtagatta tgcattggat aaagacttaa tagttgtgtt ggatttacac cattttgaag
    72181 aaattatgaa agaaccaaga gttcataaag aaaagttttt aaaaatatgg caacagatag
    72241 ctaataggta tcaaaaatat gataaaaaat tggtatttga attattaaat gaacctaaag
    72301 aaaatttatc ttcacaatta ctaaacgaat acattgaaga agcaataaag ataattagaa
    72361 aaactaaccc caaaagaact attatagtag gaccatataa tttctatcaa attgattatt
    72421 tgaatgaatt aaatattcct aaagattcta atatagtagt ttcttttcac tattacgagc
    72481 caaatgattt tgcatttcaa ggaaatatct atcataaggg atttgagcac ttaagcaata
    72541 ttacttggga aggaacaaat gaacaaatgg attatttaaa aaaaaggttt gatactgtgg
    72601 aaaattgggc aaataaaaat aaggtaaaaa tcttcttggg tgaatttgga ataacaaaag
    72661 aggcaccaga agtttcaaga agagcatgga taaaagctgt aagagaagaa gctgaaaaac
    72721 gaaacttttc atgggcttat tgggagcttg catctggatt tggtatatac aatcaaattg
    72781 aagggacttg ggatagagat atattaagtg cattaataga aaagaggtga ttttatgaag
    72841 aaaaattcaa aaaagatact tataacttta actattatta ctaatgtcat atatatattg
    72901 tggagaattt tttacacagt acctaaagaa gaagggaagt ttgccttaat atgtgccata
    72961 atacttcttt ttgtagagat aatgggtatg atggaaatgt ttgtgcatta ttatggtatg
    73021 tcaaatattg agtatcctga aaaaccaatc ataagtgaag aactttatcc acatgtagat
    73081 gtatttattg caacatataa tgaatctgtt gatttggtta gaaaaactgt aaatggatgt
    73141 attcatatgc agtatccaga taagaaaaag gtacatatat acatatgtga tgatggaaat
    73201 cgtgaagaaa tgcgtattct agcagaaaaa atgggtgtaa attacataac tagaactgaa
    73261 agagaaggag caaaagctgg aaatttaaat aatgcaatgc aacatacaac ttctcctttg
    73321 attgctacat ttgatgcaga tatgatacca atgcatgact ttttaattgc tacagtacca
    73381 tactttttaa aaaatgagca agctaaaaaa gatggagaaa aagaggagta tgaaaaggtt
    73441 ggttttgtgc aaactccaca gagtttttat aatccagatt tgttccaatt taatctgcac
    73501 tctgaaggaa ggattccaaa tgagcaagat tatttttaca gagatattca attggctaga
    73561 aataggacaa attctgtaat ttatggtggt agtaatacag ttatttcaag ggaagcactt
    73621 gaagaagttg atggatttta tacttattct attacagaag attttgcaac aggtatctta
    73681 attcaaagta aggggtatag atgttatgct attccagaag tacatgcatc aggtttatct
    73741 cctacagatt taaaaagtct tattaagcaa cgtgaaagat gggcacgtgg atgtatacaa
    73801 actggtagac gtctaaatat tttgtttagg agaggtttag gtttttggca gaaaataagt
    73861 tatatttctt caattactta ttggtatgca agtataaaac gctttgtata tataatggca
    73921 cctattttat tttctgtgtt taatgtgatt gtagtaaaat gtacgttact tcaagtattg
    73981 gtattttggt tgccaatgta tattttaagt agtttatctc ttaaaatatt ttctcaaaat
    74041 ataagaaata ctagatggac caatatatat gaaactataa tgtttcagtc tttaatgcca
    74101 gcagtaatac ttgaaacgtt tgcaatatct aaaaataaat tttcagtaac aaataagagt
    74161 aaattagaag aaaatagaat gtataagttt ttacagggaa taccttattt tatttacatg
    74221 gtcttatcta tcataggaat tttaaaaatg tttgtagcaa tatttaaaat gagttcaatg
    74281 acatattcag ttgtattatt ttggttgatt ggaaaccttt ttaaccttgt tatggctaca
    74341 ttatttatat cagggagaca gcagttaaga aagtctgagc gttatattgc tgaaattgat
    74401 tttaagttaa agcaaaattc ttatgttctt tcttcaaaaa caattgatat atcagaaaat
    74461 gggtttgcat ttttgctaga aaatccagaa tatatttcac cagaagaaga gtttgaggta
    74521 gagtttagag aaaaatctgg aaatgaaatg tatatagcca atatgaaagc aaagattgtt
    74581 aatgttgtgg aagtaaattc aaagtggaaa tatgcagctt atattacaca tattgaagat
    74641 agtgaaatag ataattggat gtgtattgtt cacgatagaa tacctacttt accaatgaca
    74701 atatctaatc aactaggttt ctttgatgat ttgcaaatta atgtgaaaaa acgtattgaa
    74761 aaaactagaa cattatcacg aagaagtcca agaatcaata tgaattttca gatggatata
    74821 aaaaatacag gtaaattaag aatagtgaat tttaattatc aatatgtatt attaaatttt
    74881 gagaataaaa gtatttatcc taaagaaata gcattggaaa ttaatgaaaa tattgtgtta
    74941 gaatgtgatt tgtgtgaggg taaaattgat gaaagaggta tcttatataa agtaaataac
    75001 attgacagca taatgcaaaa tttcttttta agagatgaaa tgatggattg gatattacaa
    75061 aataagacaa ttcttgtttc aaagcctagt gaaaagaagg aaaaaagtat agatgagttt
    75121 gaacccatgg aatatattta ggagagatga aatgaagact ttaaaagtgt ttttttgttc
    75181 tacaaaatat cttattttgg tgtttatttt ttttataaat actactttta taagttcagc
    75241 aacaagtgat aaaattttag atttgtcctt taaaaagata gagactgact taaattctaa
    75301 gattacatat gaagatacag gtgtaaaaat agaaacggat agttctaaaa gcgataagga
    75361 acgttattta tatatttacc aaaatataaa agaaaattgg agcatgtata ataattttta
    75421 tattgaaatt caaaataaaa ataaaagttc tcagagaata aatttaagca tacaaagtaa
    75481 aaatatgctt gaatttagat taaaagaagg tagtgaagta tttttagaag gtaaaaatat
    75541 aatatattca gataaaataa aagaaggatg catagaagta ccaggtgaat ttgaaggcaa
    75601 aatttatgtg aactttaata gccttataaa tgaggaaagt aatgttgtgc tggactcaaa
    75661 tatgctttca aacattgtta gttggggaat tacgtttatt ccatctgatg aagaacataa
    75721 tattgttatt ataaaaaaga tatctttatt gtctgaagag aaattaagat ttttaaataa
    75781 tattaaaata attggcgatg aagaagtaca aataccagta ttgggtcaaa gtataagtca
    75841 gtatgaagta ttaggtctta aaagtgattc taaaattaag tactctctta tgggaaaaca
    75901 agataatgta agcatatctc aaaaaggtaa attaacatta agtaataaag ccaaacctgg
    75961 acaaattatt ttacaagtta atgttgatga taagtttaaa attggaaaga aaataacatt
    76021 aactgagtct tggagtgtta ataaaaaaga taaggatggt gttccatata cattagtata
    76081 tcctgagcaa tcaccaacag tacaagatat gaaaaaaata aactttatga ataacatcat
    76141 aacgtttgtt cgaattttat ttgtatctct agtaataata tgctttggaa tatatttata
    76201 ttggaaaaaa tgttcaaaaa ctaagtaaag agaggaggtt agattgtgtt attttcaagt
    76261 ttaatttttt tattttattt tttacctata actttggttt tatattatgt atttaggttt
    76321 aaccgaacga tacagaacat gatattgctt gctgttagtt tattttttta tgcttgggga
    76381 gagccaaaat ttgttgttat catgatagtt tccataataa tgaactatat atttggttta
    76441 ctggtagata gatataggga aagtaaaata aaagtaaaag tttttttagt tttgatgtgt
    76501 gcatacaata taggtgtttt atttatattt aaatatctag cttttgcgct aagaaatatt
    76561 agtgaactta ttagtactga attgactata cctagtattg ttttacccat aggaatttca
    76621 ttttttacat ttcagggaat gtcttatgtt atagatgtat atcgtagaca tggagaagtc
    76681 caaaagaacc ctttttatgt gggattgtat atagcatttt tcccacaatt aatagcaggt
    76741 cctatagtta gatatgagag tgtggcagaa caaattctca atagaaaaga aacttggaat
    76801 aaattttcta ttgggacttg taggtttata acaggtctag gtaaaaaagt attaatttca
    76861 aataacatgg ctatagtagc agactatatt tacactatga atagtcaagg agaaatagct
    76921 gcatcacttg catggcttgg ttcaatagcc tatactctgc aaatattctt tgatttttct
    76981 gcttattcag atatggctat aggcttaggt cttatgtttg gttttaaatt tgaagagaac
    77041 tttaattatc catatatatc aaaatcaatt agtgagtttt ggagaagatg gcacatttct
    77101 ttgggaatgt ggtttaagag ctatatatac tttccgcttg gaggttctag agtagcaaat
    77161 aaagatatta tgattagaaa tatgtttata gtgtggttat ttactggaat atggcatgga
    77221 gcagaatgga catttgtaat ttgggggatt ttaaactttg ttttcctaat tatagagcga
    77281 tttataatgt ttgaaaagat tgaaaatcac aattttataa aacatattta tgctttatta
    77341 gtagttaatt ttgggtgggt attatttagg tcacctaatt taaaagaagc atataattat
    77401 tttaaagcta tgtttggagg caatggagct atatggagtg attatacata tatgttttta
    77461 aaagaatact gggttttctt tatatttgca tttattttta gtgtacctat tgcaaagaaa
    77521 atcaataagt ttgttgttga acaagctaaa tatagtatga tatttaacgt attttatcca
    77581 atctcagcta ttttattgtt ttttatttct gtgacatatt tagtaactgg aagctataat
    77641 ccatttattt attttaattt ttagttggga ggaaaagtat gaatagattt tttaaagtaa
    77701 gattaataac tgcaattatg ttcttaatta ttttattcgc tttctctatc tttaatgttt
    77761 gttattctgg aaaagatacg atacaggaaa taaaaaattc aatagctgaa aaaagtagtt
    77821 taaaagatac aatatcatct attgataata cagtgaatga caaagtaata tacaaaaata
    77881 cgttcattga aacttatggc tatttacaaa aattaatggg taaaaatgag ttttcaaaat
    77941 ttagtgttgt aaaagatact tctggaaaga tgcattatac atattttgct aaagctccaa
    78001 atccagttgg tgtgatagca gatagggtaa gaaaattttc tgatgaaatg gaaaagcaaa
    78061 acactaaatt ggtttaccta atgactccag ataagtatat aaaaggagtg acaaaatttc
    78121 caaaaggaat accttattct tatagtaatg agacagcaga taatttttta aatcaactaa
    78181 aaaagtataa tgtggactat attgatttta gagaaaatat tttaaagagt ggtattccaa
    78241 aagatgattt attttttaaa acagaccatc actggaaagt agaaacttct ttttgggcat
    78301 ttggagaatt agttgagcaa cttaataaaa aatacaatat gaatttagat gaaaatcatt
    78361 attatagaga taaggacaat tataattcaa ttgtatatcc taagtcattt cttggttcta
    78421 tgggaagaaa gactggtatc ttatatggtg gtatagatga ttttacatta atttatccta
    78481 aatttaagac taattatact tattatacag attctaaatc tcaaaaattt gaattaaaag
    78541 gaaggtttga agagagttta atattatcat atccttttaa tgcagacctt gatttaatgg
    78601 atggtcaatc agataagtat tttacatatt tattggggaa cagaccatta gttaaaataa
    78661 aaaatataga aaatccagat ggattaaaag tgctgtttgt taaagattct ctaattgtac
    78721 caacagcagc atttttttcc tctgtttgtt catctataga tatgatagac cctagatatt
    78781 atgatggaga tatactagaa tatgcaaaat cccatgacta tgactttgtt tttatatctg
    78841 tatatcccca aaatcttaca aaagaatttt ttccgttttg tgagtaaatt tctaaaaaag
    78901 ttttctgata aaataaatgg ctaactggta aaaagttagc catttatttt gagtgttatt
    78961 ctaagaaata ttttttttac taaatacttc tttatctatt tttccaagtg attttcctac
    79021 agtaattgat gataccatag caccattaac atttatcata gtacgtccca tatctagtat
    79081 agggtctatt gcaagtatac caccaactaa tggaaaataa gaaccaagac caactccaga
    79141 gataacaact gaaacggcca ttgtagcagt tcctggaaga ccagctattc caaacgaact
    79201 aattgttata acaattaaca acataacata aaagctcata tccatgttta ctccagccat
    79261 attggcaagt gttacagcca ttaaagcagg atatatacct gcacaaccat tcatacccat
    79321 atttgcacct aaacttgctg taaagcttga tacaccctca tcaactccgt gattttgtac
    79381 tagactttct atcgttacag gcaatgttcc taaactagaa cgtgaagtaa atgccagaag
    79441 taaagcttca gttgaatttt ttatataagt aatgggattt agaccattta aagttataaa
    79501 aattaaatgt ataataaata atattgcaac tgatatataa agagctaata taaactgtaa
    79561 aacagatact attgaactaa taccttgtga agttattgta tttgcaagca gagcaaccac
    79621 agcataaggc ataaatttaa taacagtcat agacacactt acaattattt tgtaagatgc
    79681 ttctataaaa cctataaatg gttttattgt ttcaaaatgt tttttactta atctctttat
    79741 tgaggtagct ataaatgtag caaatattat tgtagctaca atatttccat ttgccatagc
    79801 cattacagga ttagatggta gtaatcctct taaagtatcc acaagagagt ttatttcttt
    79861 aagttcttga ttttcaacta aagtaggcat attagctcct acacctaact tcattatatt
    79921 tgcaacgata attccaacaa ttgcagctat agcagtagta gcaagaagca tacctaaaga
    79981 tttaaatgtc agagttccaa gattgttatc tttcatattt ataattactt ttataatgga
    80041 taagaaaact aaaggtacta ctaacatttt taataagtcc ataaatccag aaccaaatag
    80101 gctataccac ttacttactt cttgtagcca aatgacttga gttgtatcat taggaaaacc
    80161 agcaaaagct tgtattatga ttcccaatat gagtcctagt actgtagcat atattgttct
    80221 caatgaaaat tttatttttt tcttttcaaa ttgtctaaca ataaagaacg tacctagaag
    80281 taatattatg aaaaaaattg ttttaaaatc tgtaatcata agaaattgtg ataaaaatga
    80341 actttccaat atttttctcc ttttatttaa aaataaattt ttctaagttt aaatgatatc
    80401 aatatattaa aaaaatgtca atattatatc acaatttact taaatagagt aaaacaagtt
    80461 gattttgaaa aatgtgatta agtacagaaa aatagggtat aataaatgtt taaagaattt
    80521 gaattgtggt aagaaaataa aaaatagctt ttataagatt tgatttcaaa ttaaaatgtg
    80581 ttaaataaat aactaaaaat tattataaaa aatgttttca tagaatatat atcaaatgaa
    80641 aagcttaaaa taagtgaaga aattaactag acatcaaagg agagataaaa tgagagtaat
    80701 aataattggt ggtgttgcag ctggtatgag tgctgcagca aaattaaaaa gaataaaacc
    80761 tgagtatgaa gttgttgttt atgaaaaaac tgaaatagta tcttttggtg cttgtggatt
    80821 accatacttt gttggtggat tttttaatga tgctgatgaa ttattagcaa gaacaccaga
    80881 gaaacttaga gaagctggaa ttgatttaaa tatatttaga gaagtcgttg aggttgatag
    80941 tgaatctaag aaaataaaag taaaaaacat aaaaacagat gaaatatatg aagattacta
    81001 tgataaattg atgatagcaa ctggagcaag aagtattatg cctcctataa aaaacataaa
    81061 attaaagaat gtttctacat taaaaagttt atatgatgga gaatatttaa aaaaactttt
    81121 aagtaatgaa gataataaaa gagtgacaat aataggagct ggttttatag ggttagaagc
    81181 agttgaggca tgtaagaaat taggtaaaga tgtagatgta attcagttag aagatagaat
    81241 attgccacaa gtatttgata aggaaatgac ggatgtatta gaagaagaaa taaatagaca
    81301 taatgttaat ttgcacttag atgaaatggt tgtagaactt tgtggagaag ataaagtaga
    81361 aaaagttata acaaacaaag gggaaataga tacagatgta gtaataattg ctactggcgt
    81421 gagacctaat accgagtttt tgtcaaatac taatataaaa atgctaaaaa atggagctat
    81481 agtagttgat gagtatggaa gaacttctgt agaagatata tactctgctg gagattgtgc
    81541 aactataaag aatatagtaa gtaatgaaaa tgtatatgtt cctttagcta ctggagctaa
    81601 taaattgggt aggatagtag gagaaaacct agcaggaaga gaaatatctt atcaaggttc
    81661 actatcttca agctgtataa aaattatgga tatggaggca gcatcaactg gaattacaga
    81721 aaggcaagct aaagatttag gcataaatgt caaatctaaa tttatttctg attataatca
    81781 aactcattat tatccaggaa gaaataaaat atatgtaaag cttatttatg atgcagatac
    81841 aaaagttatt ttaggcggac aagtggctgg gtttaaggat gctgtccaaa gagcaaatgt
    81901 attggcagct gctatctttg gaaaaatgac cacaaatcaa cttggaatgt tagatttatg
    81961 ttatgctcca ccatttgcaa gaacatggga tgttttaaat gtagctggaa atgtatctaa
    82021 ataatattta gattatagct aatatagttg acaagcaatt aagggaatga atttacctaa
    82081 actattttta tcatggtaaa attcattcct aaatttttat tccaaatttt tattccaaat
    82141 ttttagaaat aaggattcca ttaaattatt catcaaaatt taaacgcaag cttaatctat
    82201 cttctccaag aatagtattt tcaaaaacat tagtagcatt ttctaaatac atactaggta
    82261 tgtctaaaga aggactaaaa tgagtcagta aaagttgttt gacatttcca agttttgcaa
    82321 gattagcagc ttctctaaaa gtcatatgtt tgtttctaac agcttttgat atatctaaat
    82381 catcaccata catggcttca catataaata aatcactatc ttttatgaaa tctggtattg
    82441 attctatagg tcttgtatcg gttgtaagac ttatcttaac tccctttctc aattctccta
    82501 agaccatatc tggagtgtat tgttttgaat ctaaaactat attttgacct tcttggagtt
    82561 tgttccataa tattttagga acttcgtttt tagttgcctt atctatatca aatttagggt
    82621 ttcttctaaa attaaaactg tatcctaaac actctataga gtgttctaaa ctgattgttg
    82681 aaatttctaa atttcttaaa actttattat ctaaagaaaa attgccttga gggttttcta
    82741 taatttttaa agtgtatggt acatattcta ctaaatttct catagaacgt atacaatcga
    82801 ctattccaac tggaccaact atagttaaat cacttgtacg accactattc ccaattgttg
    82861 ataaaagtcc taaaagtcca aatatatggt caccatgtaa atgggttata caaatcaagt
    82921 ctatatcttt aaagccacat ttttttagct tcatagatac ctgagtacct tcaccacagt
    82981 caattagtat ttttctacct ttatagttta taaatacaga ggatagaaat ctgtttggca
    83041 taggtacatt tccaccacat ccaagtaaag ttaaatctat cattttttcc cctttctaaa
    83101 attaacacaa atctgttgtt tgtttttatt atgatatcct attataatta ttttaacatt
    83161 aaatataaca ataaatgtgt atttgagtca agaaatattg tcaaataaag tttttatata
    83221 gcaatgtata aaaatttgga aaacgaaaag tgaaaattat atttaggagt atttaaagga
    83281 ggaaaattta atgaaagtat taaagaaaat tactattttg tcattaatta cattaacctt
    83341 agttggttgt agtaacggag aagagaaaaa agtggttgaa ggttctaaga aaactcaaaa
    83401 ttctaaaaaa gatgaacagc ctataatagt acataaagat gcaaatatat tgaaagatag
    83461 gtatgagcca ccaaaaggat ttaaaagagt tgatgtagaa aaaggtagtt ttgaatcatt
    83521 tcttaggaat actaagctaa aaaattatgg agagaaagta aagtattatg atggaagaac
    83581 taaggaatca aaaggtattt atgatagtgt atttgatgtt gatattggaa atagagattt
    83641 acatcaatgt gcagatgcaa ttatgcttat gagagcagaa tacttgtatc agaataaact
    83701 atatgatgaa ataagttttg attttgttga tggttttaag gcgaagtatt caaaatgggc
    83761 acaaggatat agaatttcag taaaagatag tggttcaagc tggtataaag caactgaata
    83821 ttcaacatct tatgagagtt tcagaaagtt tatggatata gtgtttgcat attcaggaac
    83881 gttatctctt gaaaaagaat tggagcctgt aaaagttgag gatatgaaaa taggagatgt
    83941 gtttatagtt ggtggaagtc caggacatgc aagtataatt atggatatgg cagaaaatga
    84001 aaagactggt gaaaaggtat ttatgatagc ccaaagctat atgcctgcac aacaaacgca
    84061 acttcttatt aatcgtaaaa atccaaattt gagtccttgg tatagtttag attttgaagg
    84121 tgatttgaca atacctcaat ggacttttaa aagagaccag ttgaaaagat tttaaaataa
    84181 taattttata taataaaaga aaaatataga tgtgaaaaaa tgtaattaga ttaaaactaa
    84241 ttggatatgg acaaaattaa attgatagat aaatattaaa aattacacta attaatctta
    84301 ctatagttta atatttatct aaaaagtttt atgtaaaata taaattttat attaaagcta
    84361 aaactaattt gaggaggcta atttatattg aagattagaa ggtatttaat tttggtaatt
    84421 ataattctaa ttacaacaag tcagagtttt atttcttatg ggctagagcg atttgaagaa
    84481 ataaccattt ttcacactaa tgatatacat ggaagatatg ctgaaggtga tgaccatata
    84541 caaataggaa atctagccac attgaaaaaa gaaactccaa actcaatttt agtagatgca
    84601 ggagattgtt tgcatggact tccaatagta aatatggata gagggaaaag tgcaattgaa
    84661 ttaattaaat gtgctggata tgactatatt actcctggaa atcatgactt taattatgga
    84721 aaagatagac tgtttgagtt atctaaaagt gctaatttag gagagaatac tttaaaattt
    84781 ttatcatcaa atatttttga aaatgggaaa aaagtttttg atagtaatga tataaaagaa
    84841 atagatggaa taaaaatagg attttttgga ctctcaaccc aggaaacaaa gagcaaaact
    84901 ggatttaaaa atgtggaagg attagagttt aaaaatccta tagaaagtgc aacagaacaa
    84961 gtaaatgaat taaaaggaaa gggtgccaat gtaatagttg caatatgtca tattggtaca
    85021 aatagtttaa gtaagccaaa tagtatagat atagcaaatg aggttcaagg aattgatttg
    85081 attattgatg gacacagcca cactaagttt gaaaatggta aacaagtggg tgatacattg
    85141 attgtaagtg caggacaata tttagaaaat attggcgaga taaaactaac tttggatact
    85201 aatgatgtag aagatataaa aatagaaaat aaatcagcta gattaattgg aaaagaagaa
    85261 gcattaaagt ataagcttga ctccgttgta agtaaaaagg ttgataaaat aaaagaacaa
    85321 caagaaaaaa tattagataa agttataggg gtaactacaa atactctaga tggttcatat
    85381 gaaaatgtaa ggacaaaaga aactaatttg ggtaatttaa taagtgacat tttactagat
    85441 aaaactaagg ctgatatttc tttatttaat ggagggaata ttcgagatac gatagaaaaa
    85501 ggcaatataa caagaagaga tattgtagat gtatttcctt ttagcaatac tatagttacc
    85561 aaagaactta caggagcaca gattaaagat gtattggagc atggagtaaa actttatcca
    85621 gaaaaaagtt cagccttttt gcaagtggga ggaatttcat attactttaa tcctaaacaa
    85681 aaagaaggcg aaaaaataac aaatattcaa aaagaaggaa agccattaga tttaaataaa
    85741 aagtatgtag ttgcaacgaa tgattatata gcatcaggtg gagatgaatt tccttgtttt
    85801 tcaaaagagc cagtactaaa ggaatttgga aatttagaga gtgcagtcat tgaatatata
    85861 gagtacaaaa aagaaatatc aaaaaatgta gatggaagaa ttggtattaa atctaaagat
    85921 gagttaataa gcaagaatca tgagagtgat ttgatattaa gtgaaaatga aaaaaatatc
    85981 aatgataatg aagagaatct atctaataat ataaaaagct ctgatagtga taaaaataaa
    86041 agcttagata aaacaagttc tagagaaagt tctaatctag gaatatctaa aagagaagct
    86101 aaagaaaaat ctcctaaaac aggag
//
LOCUS       DAYAKB010000008        81195 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.008, whole genome shotgun sequence.
ACCESSION   DAYAKB010000008 DAYAKB010000000
VERSION     DAYAKB010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.008"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1143
                     /locus_tag="ACGI3L_000673"
     CDS             <1..1143
                     /locus_tag="ACGI3L_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HFG9196400.1"
                     /translation="ISNNAVDSKLMNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQ
                     LRHAVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILF
                     GFFLNYLGNPDLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTF
                     IIVGYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCT
                     MGCVLLKENIGEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGI
                     LLSIFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTL
                     VEWTTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1397..3421
                     /locus_tag="ACGI3L_000674"
     CDS             1397..3421
                     /locus_tag="ACGI3L_000674"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9196401.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGSGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3641..4327
                     /locus_tag="ACGI3L_000675"
     CDS             3641..4327
                     /locus_tag="ACGI3L_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFG9196402.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4422..5477
                     /locus_tag="ACGI3L_000676"
     CDS             4422..5477
                     /locus_tag="ACGI3L_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HFG9196403.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5592..7148
                     /gene="murJ"
                     /locus_tag="ACGI3L_000677"
     CDS             5592..7148
                     /gene="murJ"
                     /locus_tag="ACGI3L_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFG9196404.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7194..8900
                     /locus_tag="ACGI3L_000678"
     CDS             7194..8900
                     /locus_tag="ACGI3L_000678"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFG9196405.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8922..9995
                     /locus_tag="ACGI3L_000679"
     CDS             8922..9995
                     /locus_tag="ACGI3L_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HFG9196406.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10007..10729
                     /locus_tag="ACGI3L_000680"
     CDS             10007..10729
                     /locus_tag="ACGI3L_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196407.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10745..11902
                     /locus_tag="ACGI3L_000681"
     CDS             10745..11902
                     /locus_tag="ACGI3L_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HFG9196408.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11905..12744
                     /locus_tag="ACGI3L_000682"
     CDS             11905..12744
                     /locus_tag="ACGI3L_000682"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9196409.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12759..13934
                     /locus_tag="ACGI3L_000683"
     CDS             12759..13934
                     /locus_tag="ACGI3L_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HFG9196410.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13963..14712
                     /locus_tag="ACGI3L_000684"
     CDS             13963..14712
                     /locus_tag="ACGI3L_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9196411.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14734..15642
                     /locus_tag="ACGI3L_000685"
     CDS             14734..15642
                     /locus_tag="ACGI3L_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9196412.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15690..16442
                     /locus_tag="ACGI3L_000686"
     CDS             15690..16442
                     /locus_tag="ACGI3L_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9196413.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16396..17763
                     /locus_tag="ACGI3L_000687"
     CDS             16396..17763
                     /locus_tag="ACGI3L_000687"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HFG9196414.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17769..18860
                     /locus_tag="ACGI3L_000688"
     CDS             17769..18860
                     /locus_tag="ACGI3L_000688"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196415.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18944..20857
                     /locus_tag="ACGI3L_000689"
     CDS             18944..20857
                     /locus_tag="ACGI3L_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFG9196416.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21059..21763
                     /locus_tag="ACGI3L_000690"
     CDS             21059..21763
                     /locus_tag="ACGI3L_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9196417.1"
                     /translation="MNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMSA
                     TVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDYL
                     TIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRVS
                     RSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMAP
                     GTNYARRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="ACGI3L_000691"
     CDS             22065..24176
                     /locus_tag="ACGI3L_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HFG9196418.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="ACGI3L_000692"
     CDS             complement(24374..25339)
                     /locus_tag="ACGI3L_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFG9196419.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="ACGI3L_000693"
     CDS             complement(25624..26580)
                     /locus_tag="ACGI3L_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFG9196420.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="ACGI3L_000694"
     CDS             26948..27736
                     /locus_tag="ACGI3L_000694"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9196421.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="ACGI3L_000695"
     CDS             complement(27859..28329)
                     /locus_tag="ACGI3L_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HFG9196422.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="ACGI3L_000696"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="ACGI3L_000696"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HFG9196423.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29236..30060
                     /locus_tag="ACGI3L_000697"
     CDS             29236..30060
                     /locus_tag="ACGI3L_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9196424.1"
                     /translation="MSKGNNNNNSRNKSKKTSHLNRKKRKLNKKKLAVLICFTVLFLF
                     IAFKATQGVVALVKSMDKSNKTNQQQNVNSEQFDLGNEEENKKKKYTVFIDPGHGGND
                     KGTESKTSNRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSS
                     ADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVEN
                     NFEVLRESNMPAILIECGFLTTPSEEQKIINEKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30375..31922
                     /locus_tag="ACGI3L_000698"
     CDS             30375..31922
                     /locus_tag="ACGI3L_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9196425.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31925..32323
                     /locus_tag="ACGI3L_000699"
     CDS             31925..32323
                     /locus_tag="ACGI3L_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFG9196426.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32363..34096
                     /locus_tag="ACGI3L_000700"
     CDS             32363..34096
                     /locus_tag="ACGI3L_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFG9196427.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34328..35539
                     /locus_tag="ACGI3L_000701"
     CDS             34328..35539
                     /locus_tag="ACGI3L_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9196428.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35732..35992
                     /locus_tag="ACGI3L_000702"
     CDS             35732..35992
                     /locus_tag="ACGI3L_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HFG9196429.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36346..38058
                     /gene="ptsP"
                     /locus_tag="ACGI3L_000703"
     CDS             36346..38058
                     /gene="ptsP"
                     /locus_tag="ACGI3L_000703"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFG9196430.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(38850..39515)
                     /locus_tag="ACGI3L_000704"
     CDS             complement(38850..39515)
                     /locus_tag="ACGI3L_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196431.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            39859..41289
                     /locus_tag="ACGI3L_000705"
     CDS             39859..41289
                     /locus_tag="ACGI3L_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HFG9196432.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            41657..42235
                     /locus_tag="ACGI3L_000706"
     CDS             41657..42235
                     /locus_tag="ACGI3L_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HFG9196433.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITISSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            42265..42411
                     /locus_tag="ACGI3L_000707"
     CDS             42265..42411
                     /locus_tag="ACGI3L_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HFG9196434.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            42707..44086
                     /gene="scfB"
                     /locus_tag="ACGI3L_000708"
     CDS             42707..44086
                     /gene="scfB"
                     /locus_tag="ACGI3L_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HFG9196435.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            44115..44612
                     /locus_tag="ACGI3L_000709"
     CDS             44115..44612
                     /locus_tag="ACGI3L_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFG9196436.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            44910..46574
                     /locus_tag="ACGI3L_000710"
     CDS             44910..46574
                     /locus_tag="ACGI3L_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC1 kinase family protein"
                     /protein_id="HFG9196437.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEAIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            46587..49037
                     /gene="recJ"
                     /locus_tag="ACGI3L_000711"
     CDS             46587..49037
                     /gene="recJ"
                     /locus_tag="ACGI3L_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFG9196438.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            49050..49562
                     /locus_tag="ACGI3L_000712"
     CDS             49050..49562
                     /locus_tag="ACGI3L_000712"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFG9196439.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            49636..51843
                     /locus_tag="ACGI3L_000713"
     CDS             49636..51843
                     /locus_tag="ACGI3L_000713"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFG9196440.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            51868..52317
                     /gene="dtd"
                     /locus_tag="ACGI3L_000714"
     CDS             51868..52317
                     /gene="dtd"
                     /locus_tag="ACGI3L_000714"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFG9196441.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            52332..52946
                     /locus_tag="ACGI3L_000715"
     CDS             52332..52946
                     /locus_tag="ACGI3L_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9196442.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            53037..54593
                     /locus_tag="ACGI3L_000716"
     CDS             53037..54593
                     /locus_tag="ACGI3L_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HFG9196443.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            54583..55845
                     /gene="hisS"
                     /locus_tag="ACGI3L_000717"
     CDS             54583..55845
                     /gene="hisS"
                     /locus_tag="ACGI3L_000717"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFG9196444.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            55919..57706
                     /gene="aspS"
                     /locus_tag="ACGI3L_000718"
     CDS             55919..57706
                     /gene="aspS"
                     /locus_tag="ACGI3L_000718"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFG9196445.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            58165..59397
                     /locus_tag="ACGI3L_000719"
     CDS             58165..59397
                     /locus_tag="ACGI3L_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HFG9196446.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMNCFGIKDK"
     gene            59411..60217
                     /locus_tag="ACGI3L_000720"
     CDS             59411..60217
                     /locus_tag="ACGI3L_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HFG9196447.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(60329..61198)
                     /locus_tag="ACGI3L_000721"
     CDS             complement(60329..61198)
                     /locus_tag="ACGI3L_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9196448.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            61570..62997
                     /locus_tag="ACGI3L_000722"
     CDS             61570..62997
                     /locus_tag="ACGI3L_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HFG9196449.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVEIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(63074..63343)
                     /locus_tag="ACGI3L_000723"
     CDS             complement(63074..63343)
                     /locus_tag="ACGI3L_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196450.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(63346..64788)
                     /gene="nhaC"
                     /locus_tag="ACGI3L_000724"
     CDS             complement(63346..64788)
                     /gene="nhaC"
                     /locus_tag="ACGI3L_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFG9196451.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(64813..65979)
                     /locus_tag="ACGI3L_000725"
     CDS             complement(64813..65979)
                     /locus_tag="ACGI3L_000725"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9196452.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(66204..68324)
                     /locus_tag="ACGI3L_000726"
     CDS             complement(66204..68324)
                     /locus_tag="ACGI3L_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9196453.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQNFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            68557..68958
                     /locus_tag="ACGI3L_000727"
     CDS             68557..68958
                     /locus_tag="ACGI3L_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196454.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            69001..69294
                     /locus_tag="ACGI3L_000728"
     CDS             69001..69294
                     /locus_tag="ACGI3L_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFG9196455.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            69309..69749
                     /locus_tag="ACGI3L_000729"
     CDS             69309..69749
                     /locus_tag="ACGI3L_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HFG9196456.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(69841..70314)
                     /locus_tag="ACGI3L_000730"
     CDS             complement(69841..70314)
                     /locus_tag="ACGI3L_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9196457.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(70314..71102)
                     /locus_tag="ACGI3L_000731"
     CDS             complement(70314..71102)
                     /locus_tag="ACGI3L_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9196458.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            71430..72674
                     /gene="glyA"
                     /locus_tag="ACGI3L_000732"
     CDS             71430..72674
                     /gene="glyA"
                     /locus_tag="ACGI3L_000732"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFG9196459.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALITSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            72997..74094
                     /locus_tag="ACGI3L_000733"
     CDS             72997..74094
                     /locus_tag="ACGI3L_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196460.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            74085..74783
                     /locus_tag="ACGI3L_000734"
     CDS             74085..74783
                     /locus_tag="ACGI3L_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9196461.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            74786..75850
                     /locus_tag="ACGI3L_000735"
     CDS             74786..75850
                     /locus_tag="ACGI3L_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFG9196462.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            76033..76737
                     /locus_tag="ACGI3L_000736"
     CDS             76033..76737
                     /locus_tag="ACGI3L_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196463.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            76730..78052
                     /locus_tag="ACGI3L_000737"
     CDS             76730..78052
                     /locus_tag="ACGI3L_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HFG9196464.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            78239..79612
                     /locus_tag="ACGI3L_000738"
     CDS             78239..79612
                     /locus_tag="ACGI3L_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196465.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(79984..80922)
                     /gene="pdaA"
                     /locus_tag="ACGI3L_000739"
     CDS             complement(79984..80922)
                     /gene="pdaA"
                     /locus_tag="ACGI3L_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HFG9196466.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        31849 a         8878 c        13995 g        26473 t
ORIGIN      
        1 atttcaaata atgctgtaga ttctaaactt atgaatagta ggattaaatc aatagatata
       61 ataagagggc tatcaatagc cctcatgata gtctgcaata atcctgggac ttggatgaga
      121 atgtatcctc aattaagaca tgctgtatgg catggtgtaa cacttgcaga ttttgcattt
      181 cctttttttg ttatatcttt aggtgttaca attccaatat caataaatag taaactaaaa
      241 aataataaat ccacactgag tataatactt agtatattca agagaagtat cttattgata
      301 ttatttggat ttttcttaaa ttacctagga aatcctgatt tagatactgt aagaatactt
      361 ggagtacttc aacgtatggg attagtctat tttgtgacta gtttagtata tttactacta
      421 aaaaaattaa atgttggaag tactgctaca ataattactt ttctatgtat atctacattt
      481 ataatagttg ggtactacat attagcaaaa ccttatggat ttgagctaga aggttctctt
      541 gcacagttag tggatttaca tttcttcaag ggacatttgt acaagccgga atttgaacca
      601 gatggttttt taactagtat agtagcaatt tcttcaggta tgttgggatg cactatggga
      661 tgtgtacttt taaaagaaaa cataggagaa tataaaaaat tctttaaaat actggttatg
      721 agcataatcc tgctaatagg tgcttttatc tttaatcagt attttccatt taataaaaga
      781 ttatggtcta gctcatttgt acttttaatg gctggcagtt atggtatatt actgtcaata
      841 ttttatttta tatgcgacat caaaaataaa agtaaaatat ttaccccaat aatagcactt
      901 ggaagtagcc ctatttttac atatatgtgc cttgaaatat tgagtcatgt tttttggaat
      961 gttccaaaac ttacgaacaa agtcgattat ccaactacct tggtagagtg gactacatat
     1021 gaacttataa caccttgggc aggtacaact tgggattctc ttatattttc tttattgtat
     1081 gtcctattct gggttatagt aatgtctata atgtacaaga aaaaaatatt tattaaaatt
     1141 tagtgcaata tttttagatg ataaagtctt tgatttgttc aaatatacgg aaactatcaa
     1201 atataatcaa aatttctcct cgataaaatt taaaaaccat gccataaaag attacaaaaa
     1261 gtttacaatt tgtaattttt tgtgctataa tgaaaaaaga tttacataat attgaattta
     1321 tgtaatataa aacaagctta agatgtatta aaaaagattt aaagatttaa agaaccaaaa
     1381 aattaggggg gatatgatga aaaaaacaac aaaattattg gcaacaggaa tgttgtctgt
     1441 agcaatggtg gcaccaaatg tagctttagc ggctgaaaat actactgcaa atacagaatc
     1501 taattcagat attaatataa atttacaaag aaaaagtgta gtgttaggaa gtaaatctaa
     1561 tgcaagtgta aaatttaaag aaaaattaaa tgctgattca ataacattaa attttatgtg
     1621 ttatgatatg ccacttgaag ctactttaaa ttacaatgaa aagacagatt catatgaagg
     1681 tgtaataaac tataacaaag acccagaata cttaaatgta tgggaacttc aaagcataaa
     1741 aataaatggt aaagatgaac agaaagtttt aaacaaagaa gacttagagt ctatgggatt
     1801 aaatcttaag gattatgatg ttacacaaga gtttataata agtgatgcaa attcaacaaa
     1861 agcagtaaat gaatatatga gaaaaacttc tgcaccagta aaaaaacttg ctggagctac
     1921 tagatttgaa actgctgttg agataagcaa acaaggttgg aaagatgggt ctagtaaggt
     1981 tgtaatagtt aatggagaat tagcagcaga tggaattaca gctactccac ttgcatctac
     2041 atatgacgca ccaatattac ttgcaaataa agatgatata ccagaaagta caaaagcaga
     2101 gttaaaacgt ctaaatccaa gtgatgtaat aattataggt gatgatggtt cagtttcaca
     2161 aaaggcagtg tctcaaatta aatctgctgt aaatgtaaat gtgactcgta ttggtggagt
     2221 tgatagacat gaaacatctt tacttatagc aaaagaaata gataagtatc atgatgttaa
     2281 taaaatatac atagcaaatg gatatgctgg tgaatatgat gctcttaata tttcatcaaa
     2341 agctggtgaa gaccaacaac ctataatatt agctaataaa gattctgtac cacaaggtac
     2401 atataattgg ttatcctcac aaggtttaga agaagcttat tacataggtg gtagtcaaag
     2461 tttatcatca aaaattatag accaaatatc taaaatagca aaaaatggta cttcaaaaaa
     2521 tagagtttct ggagcagata gacatgaaac aaatgcaaat gtaattaaga ctttctatcc
     2581 agataaagag ttgagtgcaa tgttagttgc aaaatctgac ataatagttg attcaataac
     2641 agcaggacct ttagcagcta aattaaaagc tccaatactt ataactccaa aaacttatgt
     2701 ttctgcatac catagtacaa acttatcaga aaaaacagca gaaacagtat atcaaattgg
     2761 tgatggaatg aaagatagtg ttataaattc tatagcatct agtttatcaa aacacaatgc
     2821 accaacagaa ccagataatt caggttcagc agcaggaaaa actgtagtga tagacccagg
     2881 tcatgggggt tctgattcag gggcaacaag tggattaaat ggtggagcac aagaaaagaa
     2941 atatactctt aatacagcat tagcaactac tgaatattta cgttcaaaag gtataaatgt
     3001 tgttatgact agagatacag ataaaacaat ggctttagga gaaagaacag cattatcaaa
     3061 tactataaag ccagatttat ttacaagtat acattacaat gcgtctaatg gatctggtaa
     3121 tggtgtggaa atttattaca aagtaaaaga taaaaatggt ggaacaacta agactgcagc
     3181 atcaaatatc ttaaaaagaa tactagaaaa atttaatatg aaaaatagag gaatcaagac
     3241 aagaacactt gataatggaa aagattacct atatgtgtta agaaataata attatccagc
     3301 aatacttgtt gaatgtgcat ttattgacaa taagagcgat atggataagt taaatactgc
     3361 agaaaaagta aaaacaatgg gaactcaaat tggaatagga atagaagata cagtaaaata
     3421 aaatagaaaa tattaaagca aaacatatca tctcctgtta taatgtaaaa tataacaaga
     3481 gatgatatat ttttgtaaag aatcaaattg tttacaatga tgtttcttgt attgataatc
     3541 tgctcattat tgagtataat atagaaataa gtcaaaaata agatagaaat aagttgaaat
     3601 taagaattaa aaaaattttt attccaatat ggaggtaact atgtctggat atactaatga
     3661 tgagtgtgaa atacctaaaa ttaaaagcta tccaggggca gataaagaaa ttgcaagtga
     3721 gattgactat agcatagtaa aaggaacagt tttattcgac ttgtaccaaa gaattatgga
     3781 tttagtttta tctataatag gacttgtgat aggtttacct ttaatagcaa tatttggaat
     3841 tcttattaaa atagaggaca aaggaccaat aacttataag caagaaagac taggaaaatg
     3901 cgggagaaga ttctatatat ataaattgag atctatgaga acagacgcag aaaaatttgg
     3961 cgcacaatgg gctgaaaaag atgatcctag aataactaag gttggaaagt ttattaggaa
     4021 aactagaatt gatgagattc cacagctgtt taatatatta aagggggaca tgggcttaat
     4081 aggtcctaga ccagagagac cgaactttac tgttcaattt aatgaggaaa tacctggatt
     4141 tatcaacagg ctcgctataa aacctgggct tacaggttgg gcacaagtaa atggtggata
     4201 cgaaatcact cctgaagaaa aacttaaaga agatatttac tatataaaaa ataggagtat
     4261 attacttgac tttaagatac tctttaaaac tgttaaagta gtattgacag gagacggagc
     4321 tagataattt taaaatatta gattactaat caatgaaaaa gctctttaaa aagagctttt
     4381 ttattgtcaa aaaatacaaa aaagaaaagg aatgagaact tatgattaaa aaaatttcta
     4441 ctatattatc gttagttttg ttaatctcta tttctagtac gataggagta tttgcagatg
     4501 caaatcccaa aagagaattg atagaaggga gtataccaga gatttcgaca gaattaaata
     4561 aaagagcatt taaggattct aaagaagtaa ttcttgtaaa tgaagagtca attgtagata
     4621 gtataagtgc aacaccttta gcatatgcaa aaaatgctcc aatagttgta actaagagta
     4681 aaaatcttgg tagagtaaca agaaattatc taaaagaact aggtccagag aaggttacga
     4741 tagtaggtgg tttaaaggca gtatctaaag atgctgaacg taatatagaa aaaatgggaa
     4801 tgaaagtaga aagaataaga gggaaagaca gatatgatac atctttaaag atagctagag
     4861 aaatgtatag aacagtagga tttgatgaag catttttact tagctcaaca acaggattag
     4921 agaacgccat atctgtatat tcttatgccg ctaaaagtgg aatgccaata atatgggcta
     4981 aagatgaagg gtttgaggaa caaattgatt tcttaaaagg caaaaatctt aaaaaaatat
     5041 atgcattagg tgattcaaaa gagtttattg cagagattga ttctaactta aaaaatatag
     5101 aaggaataaa gcaaataaat aagtcaagta caaatgttga tttaataaag aagttttatg
     5161 atgaaaaaga tataaagaaa atctatactg ctagattaga ctttggtagt agatctgatg
     5221 taaacgaata tatttctttg ggagtagtat cagcaaaaga aaatatgcca atactgattt
     5281 gtagtgataa cttaagtcgt gcacaagata aattcttgaa agatagcaat ataaatgatg
     5341 tagttgaagt tgggtataca gtaggtgatt atagtctatt taagagcata tttaatctaa
     5401 cattcttatc ttgtatagta ttaatactat tattactatt gattacattt agggcactta
     5461 gatatgagtc gaaatagttt ttgatttata aggaagcttt tcataggtta aatttactta
     5521 attagaataa tgtttataag cagttttaaa agttctactt ttagagttta aattagataa
     5581 ggagaaagaa gatgtcaaaa acagctaaag cagcattgtg gattatggca gccactatgt
     5641 tttcaaaagt attaggtttc cttagagaac ttgtacttgc aaatttctat gggacaggta
     5701 tgtatgcaga cgtatttgta ttaacattaa atatacctgg tttaatcata gcagtcatag
     5761 gctctgcagt tgctacaact tatataccta tgtactttga gacaaagaaa agactcggag
     5821 atgaaggtgc cttaaaattt actaataatg ttttaaatat atgctatata atggctatag
     5881 taatagctat tattggtctt ttatttacag agcaatttgt tacagtattt gcagcaggat
     5941 ttagaaacga ccctgctaag ttccaagcag caatattatt tactaaaata atgatttcag
     6001 gagttttatt cctgagtgga agtaagatat ttagttcgtt tttacaggtg aatgacagtt
     6061 ttgtaattcc tgggcttata ggaatcccat ataatattat aataatagca gcaatagcac
     6121 taagtgcagg taaaaatgta tggatactgc cagcaggagc actattggct atggcaagtc
     6181 agctattgtt tcaactgcca tttgcgttta agaagtccta caagtataag ccatatataa
     6241 atttaaagga tgagtccata aaagagttag tcaacctagt attgcctatg ttggtaggag
     6301 tagctgttgg acagttaaat atatttgttg accgattatt ggcaaccact ttgggtgatg
     6361 gaaagttgtc tgctcttaac tatgcaaata ggctaaatga gtttgttatg gcattatttg
     6421 ttacatctat aataacagtt atatatccta aactagcaaa aatgtctggt aaagataata
     6481 aagaaggatt tataagtact attgtaaaat cttcaaattg tattatattg gtggtgcttc
     6541 ctatatctat aggagctatt atattagcag agcctcttgt tagaatatta ttccaaaggg
     6601 gtaaatttga tgcgttatca acagacctta catctatagc gcttagatta tattcactag
     6661 gtttattggc ttgtggagta agagatgtct tatatagggc attttactct ctttcagata
     6721 caaaaacgcc aatgataaat ggaagtatag ctttaataat aaatatagtt cttaatttaa
     6781 tattgataag accattgggt catgcaggta ttgctatatc aactagtaca tcaaacataa
     6841 ttacagttat attattattt atatctctta aaaagaaaaa tggatatttt ggaggggata
     6901 aaattataaa gactggtcta aaaagtttgg tagcatctgg tgtgatggca gtagctactt
     6961 tattgatata taataatcta tatgcattta tgggttcagg aacaattaaa gaaattatat
     7021 cagttggagc tggagtatta ggtggagctt ctgtatatac tgtattgata gttttattta
     7081 aggtagaaga gatggattta gcttttgaat ttttaagaaa aggaaaacaa aaactactta
     7141 gaagatagat aattaccttg aaattttaaa ttagagtcag aaaggatgaa aatatggatt
     7201 ataagaataa ttatgagatg tggttaaatt ctccttattt tgatgaacaa acgaaaaatg
     7261 agctattaag tataaaagat gatgaaaaag aaatacaaga tagattttat aaaaatttag
     7321 agtttggaac aggtggttta agaggtataa taggagcggg aactaataga atcaatattt
     7381 atactgttag acgtgcgaca ctgggcgttt taaattatat catgaaaact caaggagaag
     7441 aaggtaagca aaagggaata gttatagcac atgatagtag atacatgtct agggagtttt
     7501 gtatagaagt agcaaagact ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat
     7561 taaagcctac accagaactt tcttttgctg ttagatattt aaagtgtgct atgggaatag
     7621 taataacagc aagtcataat cctaaagaat acaatggata taaagtatat gactcagatg
     7681 gtggtcaaat ctgtatagat atggcaaatg atataatagc agaagttaat aagattgatg
     7741 attacagtac tattaaaagt atagattttg aagaagcttt atctaaaaat ttaataacta
     7801 tattagataa tgaagtagat gatgagttta taaaagctgt taagaagcaa gttttaagac
     7861 aaaatataat agatgaatac gggaaaaaat taaaaataat atatacacct attcatggta
     7921 caggaaataa gccagtaaga aaagtcttaa atgaatgtgg ctttgaaaat gtaatggtag
     7981 ttaaggagca agaattgcca gattctaatt tttcaacagt aaagtatcct aatcctgaag
     8041 aaaagtcagt gtttaatata gctattgaaa tggcaaagaa caatggcact gatttgataa
     8101 taggaacaga ccctgattgt gatagagtag gtatcgttgt aaaagattca agtggtgaat
     8161 atgtagtctt aaatggaaat caagtcggtt cacttttagt tagatatata ttagagagtt
     8221 tagttgaaga aaataaactt cctaaaaaca atcctacaat aataaaaact atagttacat
     8281 cagaactagg tgcaaaaata gcaaaggctt ataatgtaga ttgtttaaat actttaacag
     8341 gatttaaatt tataggagaa aaaataaaag cgtttgaaga aagcaatgat agaagtttta
     8401 taatgggata tgaggaaagc tatggttact taattggaac tcatgctaga gataaagatg
     8461 gtgttgtatc ttcacttatg atatgtgaaa tggcagcata ctattcttca aaaggtatga
     8521 acttgtatga agctttgata gatacatata ataaatttgg atactacaaa gaggacttaa
     8581 agtcagtaac tttaaaaggc atagatggaa taaaaaaaat aaaagagatg atgctttact
     8641 ttagaagtgt taaaatagat aatgtggctg atgtaaaagt agataaaatt ttagactata
     8701 aagatggtgt tgatgattta cctaagtcag atgtacttaa atttttactt gaagatggct
     8761 cttggatagc tataagacct tcaggtacag aacctaaaat taaattttac tttggagcaa
     8821 attcagacaa tcaagaagat gtagaattta agttgaacaa tttaatatct tatatattaa
     8881 atgtagtgga ttctatataa aaagctaagg ggagataaat aatgaaagta tacaatgtca
     8941 taatggctgg aggaggagga actcgtttct ggccacttag tagacaagaa gtacctaaac
     9001 agcttataaa tttaagtgga gaagatgctt taataaacga aactataaac agaatagatt
     9061 ctctagcaaa aaaagatgat ttatttatag taaccaatga gaagcaattg gaagctttaa
     9121 aggatatagt aaaagataaa tgtttggata gtaatatatt gccagagcca tgtgccagaa
     9181 atacagcagc agctataggt tttgcagcat ttaacataat gaaaaaatat ggtgatggtg
     9241 ttatgtgtgt atatccagct gaccattata taaaagatga aaaagaattt aaatctattt
     9301 tggaaaaagc tatctatata gcagaaaata atgataaact agtaactatt gggataactc
     9361 ctacatttcc atcaacagga tatggataca taaattttaa tagagaaaat actatagaag
     9421 atgttgcata tgaggtagtg gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat
     9481 atgtaaactc taaaaagtat gtatggaata gtggaatgtt cgtatggaag gtatctaaaa
     9541 tactagaaga ttttaagaga tacttgccaa aagtatatga aaaattagaa gatataagta
     9601 aatacttagg aacaaaagaa gaaatggaaa aaataaaaga aatataccca actatacaat
     9661 caatctctat agattatggt attatggaaa gaagtaatga tgttatagta gttcctggtg
     9721 attttggatg gaatgatgtt ggttcttggg attctctagg tgcaatatat ccaactgatg
     9781 atgaaggtaa tatcaaaaga ggtgaaaata ttactataga tactaaaaat tcaattatat
     9841 attcagatga caaattaata tcaacaatag gtattagtga tttgatagta gtatctacaa
     9901 atgatgcagt tatggtttgt agaaaagata aagctcaaga tgtcaaaaaa atagtagagc
     9961 agttaaaaga agaagataga caagaatata tgtaggaggt gttcatttga ttcctaaaaa
    10021 aatacattat gtatggtttg gtggtccaaa aggaaatata gaaaatatat gtataaattc
    10081 ttggaaagaa aagcttccag aatatgagat agtagagtgg aatgaaaaaa actttgatat
    10141 agagaaagaa ataaaaggaa ataagttttt ggaagaatgt tataaaagaa aactttgggc
    10201 attcatatct gattatacaa gaataaaagt actctatgaa caaggtggag tttatatgga
    10261 tacagatatg caaatattaa aggatataac tcctctttta gaaaataata ggctaatctg
    10321 tgggtatgaa gatgatagag agtatataaa tggtgctata ataggtgtag aaaaaggaca
    10381 tcctttttta aaagacttat tggagtatta tgaaaaagaa gtacttactt cttcattgtt
    10441 tacaatacca aagataatga ctcatcttat ggaaaagaat tataagaaga ttgacccaaa
    10501 taattatgaa gaaggaatac gtgtttacga caaagaatat ttttatcctt ttggatttaa
    10561 agaagacttt acaccagaat gtataacaga aaacactttt gggatacatt ggtggggaaa
    10621 aagttgggct aaaaagagaa attatttctt agaaagcaaa cacttaacag gtgtaaataa
    10681 gatatggaag tgttgtaaaa tatttgcaag taatacttta cgaagctaaa agggagaaag
    10741 taaaatgaag actttaaatg atgatagaaa tattatgatt agaaaatatc tttatatatt
    10801 tgttttgttt atcatattac ttagaaagta tatgatatca tttattgacc caaatatgga
    10861 tatagggatg attaaatcag cgttatttta ttcttcaata ggaatactaa tgctactttt
    10921 tttatttgac aagagaaaaa gtataacaga aatggtacta gttggagttt gtgtcttact
    10981 ttatttatta aatagggaag gagctatatt attaatcgtt ttattagctg tatcagctaa
    11041 gcaaatagat gataaattta tagttaaaaa ttatttaata atatcagcat gttttttaat
    11101 ggtagctata ttattattta atctatttcc ttcattgata tttaatcagg aagtccacta
    11161 tagatatata gaaaaaatag atatgcttgt tacaagaatg gattttggac ttggtaatcc
    11221 aaatagtgta ttttatcata tggttactat atatgcagca tatatattct taagatataa
    11281 agattataat aaatgggata gaataatttt atttggttct gcattttttg tttatcaaac
    11341 cacatatagt agaactggat ttttcactat attagcagga ttaatatttg tagaaataat
    11401 aagatggata gatataaaaa aaataaaagg actaccaatg ctcctaaaga cattaccgat
    11461 aatacttact ttatttagtg taattattgg tacagtattt gataaaagca ctttattaaa
    11521 tagattatta gcaagtagac ctaagttctg gcatgtatac ttggctgaaa aggggaattt
    11581 tctaaaacct tttggaaatt catatagtcc tgctataaaa gcaactaatc cattagatag
    11641 ttcttatgta tatataatta gtgtactagg agtagttgct tgtatattat ttatgtattt
    11701 gatgtataaa ggaatagaaa gctttataga aaaagataaa aaagcatatt tagtagcttt
    11761 atttatattt ttactatact cttttgcaga aaatttatta ttagaagctt catttagttt
    11821 tgcagtagta ttactaataa aagaagtgat attaaatgat aaaagggaaa tagatttgtg
    11881 gaagatgaaa agtaggaggt agtaatgtta atatcattaa taatgccaac attaaataga
    11941 tatgatgata tatacttact tatggacagc ttagaaaatc aaacttacaa aaactttgaa
    12001 cttatagtag tagaccaaaa tgataatagc aaagttaaag aaatagttga taaatacatt
    12061 gataagttag atataaagta tataaaaagc tctaaaaaag gattgagtta taacagaaat
    12121 gtaggcatag acaatgctgt agggcaaatt ataggtttcc ctgatgatga ttgtgtctac
    12181 gaaaatgata cattagaaaa agttataaat ttctttaata aaaataaaga ttataaaata
    12241 tacagttgca aaactatgga ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga
    12301 acttgtgata tcacaagttc caacgttttg gatactataa catccataac tttttttatt
    12361 gattttgaag gtaaagacta tacaagattt gatgagaaat tgggtgttgg tggagagttt
    12421 ggtgctggtg aagagataga ttatgtttta aacttattga gtttaggttt taaaggaaaa
    12481 tactttggaa atgatataat ttaccatcct gcaaaaaaac attctaaatc taaagaaaag
    12541 tatcaaaaag attataacta tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc
    12601 tatagaaaaa attataagtt tgcaaaagtt atggtatcaa aacttgtaag aaatatagga
    12661 ggtcttatat tgagttccaa tagagattat catagtgcca ctataaaagg aagaattaat
    12721 ggatttagac agtacaagtt ataatgagga tggtgtttat ggacaaggtt aaatttttaa
    12781 taaatatgct tttggctttt tttatatatc catttaataa gcataagttt aatggtagag
    12841 atatctggct tataggtgga cattcagggg atatatacaa tgataattca aagttttttt
    12901 atgagtatat gctaaaagaa cataatgatg tagaaactta ttgggtagta aataaagaca
    12961 gtaaagtatt tgataaaatt ccaggcaaaa aattaataag aggaagtgta gaaaactatc
    13021 tgtattatta caattcaaaa gctatagtat tttcacatgc accatcagca gatatagcac
    13081 catacaattt tgctgtacct gttcttaatt attttcataa aaaaacgata aaagtgtttt
    13141 taaatcatgg gactataagt tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata
    13201 ttatagataa cctatataaa agctataata tagttacagc aagttctgaa tttgaaagaa
    13261 atgttatggt aaatgattgg ggaatgttag atgactcagt ttatataatt ggaaatgcaa
    13321 gatatgacaa tttaccaaca aatgaagttg cacaaactcg agatatatta tatactccta
    13381 catggagaga ttggataaaa tttagttcag gaaaatttac ggatacagat tattttaaaa
    13441 atataatgaa ttttttaaat gatgacaaat taaataaaat attagatgag aaagatataa
    13501 atgtaaaaat ttatatgcat catcttatgc atgagtttat agatgatata aaagaaaata
    13561 taacaggaaa acgaattgtg tttttagata aaggggtaac tctagcaaat gaaatcagaa
    13621 aatcagctgc aaatataact gattattcaa gtgtagccat agactttttg tatatgaata
    13681 gacctatttt gttttaccaa ttcgatttgg atgaatatat ggaaaaagtt gattcatata
    13741 tagatttaaa aagtgaaatg tttgggtctt tggcttataa taatgatgaa gccgtgaata
    13801 aacttattga tattattgaa aataattttg aggttatgga taaccaaaaa aatgaaagaa
    13861 ataagttttt cagatataat gataataaga actgcaagag gatatatgat tgtgtattaa
    13921 gtaaaattaa ataaatattt tataaatgat gaggaaggta atatgaagaa gaatttagta
    13981 tctataatta ctcccatgta taattctgaa aaatttattg aagcaaccat aaaatcagta
    14041 ttaaaccaaa cttatcaaga atgggaaatg ttaattattg atgattgctc aacagataat
    14101 agtcctaata tagtcaaatc ttatatgcaa caggatagta gaataaaatg tataaagact
    14161 gagactaata agggtgtctc taatgctaga aatttagcac taagtaaggc aacaggacaa
    14221 tttatagctt ttttagatag tgatgaccaa tggaatagta gtaagttaga aaaacaagta
    14281 aattttatgt tagaaaatga ctatgtaatt tcatttactt catatgaact gatggatgaa
    14341 aatgataaaa aattaaacaa agtaataaaa gttccaccta atgtagatta tagaagatta
    14401 ttaaaaggaa atatcttagg atgtcttact gttgtgattg ataagtctaa attggatttt
    14461 gaaataagaa tgagtggtgt aagacatgaa gattatgttt tatggttatc gatattgaaa
    14521 aaagggcata ttgctcatgg aataaatgaa gttctagcat tatatagaaa atctagtaat
    14581 tccctaagtg gtaataaaat aaaagctgct atgtggactt ggaatatata tagaaatata
    14641 gaaaaaatac ctttatacaa agctatatac tactttatta attatggaat aaacggaatc
    14701 aaaaaaagtt agacagagag gaagatttaa ttaatgtata aatataaatt tactgtattt
    14761 actccgacgt ataacagagc tcatttactt gaaaatttgt acaatgattt aaaagctcaa
    14821 acttatgatt tcaatgattt tgaatggttg attgttgatg atggaagtag cgacagtact
    14881 aaagagttag ttgaaaaatt tatatcagaa aataaattaa atataagata tatatacaaa
    14941 gaaaatggag gaaaacatac tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta
    15001 tttttcattg tagatagtga tgatggttta attaaagatt ctcttgaaat tgctaatgat
    15061 gagtgggatt ctttagagaa taaagaagga tttagtggag ttgttggact ttgtgtatat
    15121 ccaagtggag atttgatagg gacagaaatg cctgaagata agaaaatatg tcactttgca
    15181 gacctatatt ttaagtatgg cgttaaggga gataaaagca tagtatttgt aactgatgag
    15241 cttataaaat ttccttttcc agaaagaaaa gaagtgagat ttttaccaga aagtgtagta
    15301 tggaatgaaa tgtctaaata ctataaagtt atatgtgtaa ataaacctat gataataaga
    15361 gattatttgg atgatggttt gactaagaat atattaagta aaaatgcatt aagaggtaga
    15421 gcattagagt ttttatattt aataaatcaa aatacatatc cattaagtag atatccatat
    15481 atgtggataa aaaattacat aaatttagcc agatactcat tgttgtctga tagtcattat
    15541 tttggtgaat taagaaaagt atctgataaa ttgttgtatt tagcattatt cccattagga
    15601 tattacaaat atattggaca aagaaaatta gtatctaagt aaacttgttg gtatagtact
    15661 gctagttgct atataaggag agtaaaaata tgaatgagcc tttagtatcg ataattactc
    15721 ctgtttataa ttcagaagag tttttatcag agacgataaa gtcaatccaa aatcaaactt
    15781 ataaaaattg gcagctttta ttagtggatg attgttctaa ggacaattca agtgaaatta
    15841 taaaaagttt tcgaaaagaa gatgctagaa taaaatatat aaagcttgaa aaaaattctg
    15901 gagctgcagt atctagaaat gttggtatta agaatgcgga aggtcgattt attgcatttg
    15961 tagatagtga tgatttatgg gatagtagaa aattagagat tcagatagaa tatatgttaa
    16021 aagaaaatgt aggtttttct tttacatctt atagatatat gagacaagat gggtcaaaaa
    16081 cgaataaggt tgcaagagct cctaagaaaa ttgactatga aggattactt agaaatacta
    16141 taataggatg ttctacagtg gtcattgata aggagattgt aggagagttc agcatgcctt
    16201 tggtaagaag aggacaagat actgcaacct ggttacagtt acttaaaaag gaaaaatatg
    16261 catatgggat tcaagaagat ttagtgaatt acagattagt tggaaattct atatcaagta
    16321 acaagataaa agcattaaaa cgaacttgga atacttatag aaatgttgaa aatttaagtt
    16381 taccaaaaag tctatatgta ttttgtttct atgtttttaa tgccattaaa aaaagagtat
    16441 aagttttata tacttggagg taaaaaaatg aaaatagcta tagctgggac gggatatgta
    16501 ggtttggtta caggtgtttg tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat
    16561 gtagatgaac aaaaagttaa atcaatgaaa cttggaatag cacctatata tgaagaaggc
    16621 ctagaagaac ttatggttaa aaattacaac agaggaagaa tagattacac tacagactat
    16681 aaaaaagctt atgaagatgt agatgtaata ttaatagctg taggtacacc tgagagaagt
    16741 gatggttcag ccaacctaga ttatataaag gcagttgcaa agcaaatagc tgaaactgtg
    16801 acaaaagata ctctagtagt aataaaatct acagttccaa ttggtacaaa tgaagagata
    16861 gaagattata taaatagaaa cctaaaaaat gatgtaaaag tagaacttgc atctaatcca
    16921 gagtttttat cacaaggaac agcagtaaaa gatactctac atgcttcaag aatcgttata
    16981 ggtgtagaaa gtgaatgggc tagagaaata ttagaggaaa tctataagcc ttttaatcaa
    17041 cctataatag ttacaaatag aaatagtgct gagatgataa aatacgcatc aaataacttc
    17101 ttagctctta aaatatcatt tatgaatgat attgcaaatc tttgtgaaat agcaggagct
    17161 aacatagaag atgtagcttt aggaatgagt tatgatgata gaataggaag taagttttta
    17221 aaggcgggaa taggatatgg tggttcttgc tttccaaaag acacaaaagc tcttcactgg
    17281 ttatctgaac ataatggtta tgaattaaaa acagtaaaag ctgcaataga agttaatgaa
    17341 agtcaaaaac ttaaattagt tagaaaggca tctaagttag tagagagctt tcaagatatg
    17401 aaggttgctg ttttaggttt gacttttaag ccagacactg atgatataag agaagcacca
    17461 tctataccaa atataaaata tttgctcgaa agaggggcaa gagttactgt atacgaccca
    17521 attggtgtaa ataatactaa gaaaatattt ggtgactcta tactttatgc tgattctgta
    17581 gatgatgcga tagaagatgc agagatatgt tttataatga cagaatggaa agatgtatta
    17641 aattatgata tacataagta taaggaaaag atgaaaaatc ctttagtcct tgatggaaga
    17701 aattgttata aaattaaaga tatggaagag ttaggaattg agtattattc gataggaagg
    17761 taaatattat gaagactgtt tgttatttag ctgatgggtc aaatcctcat actttaaaat
    17821 ggtgtagttt ttttaaaaat aaaggatatg acattcatgt aatctcttta aatggaggtc
    17881 acatggaagg aataaaaatt tataattttg gttctaatgt agaagaacta aaaaatgaaa
    17941 atatttctaa aaaaacggga tacttaggtt caataaagca gataaagaag ctagtaaatg
    18001 aaataaagcc agatatattg catgcacagt atgcaagtag ttatggattt ataggaagtc
    18061 tacttgggta tcatccatat attatttctg tttggggtac tgatatttat gatttcccta
    18121 ataatggttt tatacaaaaa caaattataa aacataactt tagaaaagca gactatatct
    18181 tttcaaatag tagagatatg gctaaagagg ctaataaata tacagctaaa catgtagatg
    18241 taaccttttt tggagtagat atggataggt ttaagcctat ggaagtagaa aaagaagacg
    18301 cttttgtaat aggaattata aagagtttag aaaaaaaata tggaatagaa tatttaatac
    18361 aagcatttaa gatgcttaaa gatgaatata aagataagaa aataattctt aaaataggtg
    18421 gctctggaag tcagatggac aacctaataa atttagctaa agaattgggt atagaaaatg
    18481 atgttcagtt tttaggaaga atatctccag aaaatgtaag caagactttt aattcttttg
    18541 atgtaactgt atttccttct ttaagagagg gatttggagt ggcagctata gaatcagaag
    18601 catgtgaagt acctgttata gttacaaatg taggaggaca tccagaatct gtatgggaaa
    18661 atgaaactgg cttaattgta gaaccaaaac aaccagaaga aataaaaaat gctataataa
    18721 aactaatgga aaatgatgaa cttagactta atatgggtaa gaaagggcgt caatttgtta
    18781 gagaaaatta tgaggttaat ttaaacttta atgatataga aaaaatttat gattctatat
    18841 ttgataaata taaaaaataa aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg
    18901 cttaggtgcg tagcttttgc tgtttaaagg agggcttcta gttatgcgag aaagtataga
    18961 tttagagaaa gaaagctttt ttaataggct ttttaaaaaa tataaattta gacatttaac
    19021 actattaatt ctagatattt gtagcgtact agtagcgttt cgaatgtctt taagcttgac
    19081 aggtaattta aatgcattta ccactaatga tataataatt tcagcgtgta tatatatagt
    19141 acttcatata gtatcattta gattgtttaa gtgctacaac acattatgga gatatgcagg
    19201 agaagaagaa attatatcta tttttgtggc aactttagct tatttaattc cgatttatat
    19261 aataaataaa ttattagggt ttgattatcc tataatgttt tatgtattaa atacaatatt
    19321 tattataatg tttacaagtg gcgcaagaat agcctataga gctataagaa tagtcatgaa
    19381 caagacatat tctagaggaa aggtttcaaa tatccttata attggtgcag gagatgcagg
    19441 agaaatggtt atacaggaac taaaaagaaa tccagaactt aaaaaagtag cagtggctat
    19501 aattgatgat gataaaaata aaattggaag aataatccac aatgtgaaaa ttgtaggaac
    19561 aacttcagat ataaaagatg tggtagaaaa gtacaatgta gatgagataa tcttttcaat
    19621 agcaaacata gagaaacgta gaaaaaaaga gattattgat atatgtaaaa acactaactg
    19681 taaaataaag acaataccag gaatttacga aattatagat ggaaaagttg atataaaaca
    19741 gattagagaa gtagagatag aagacttgtt gggtagagag cctataaaaa caaatttaag
    19801 agagataagt aattacattg agggaaaagt aatcctaata actggaggag gaggctcaat
    19861 tggttcagag ctttgcagac agattgcagg atttaatcct aaagagctta ttatagttga
    19921 taattatgaa aataatgctt actcaataca acaagaattg cttagaaaat ataaaaataa
    19981 attagattta aaaacagtaa tagcatcaat aagagaagaa aaaagaatgg atgaaatatt
    20041 taataaatat aaaccagaag tggtatttca tgcagcagca cataaacatg ttcctcttat
    20101 ggaatcgagc cctggcgaag ctataaagaa taatatattt ggaactttaa acatagctgg
    20161 cttgtcttca aaatatagag ctaagaaatt tgtccttata tctacagata aggctgtaaa
    20221 ccctactaac ataatgggag ctactaaaag agctgctgaa atgattatac agactatgaa
    20281 tgctgaaagc cagactgaat ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg
    20341 tagtgtaatt ccacttttta agaagcaaat tgaagatggc ggaccagtga cagttactca
    20401 tccagatatt attagatatt ttatgacaat accagaagca gtaggcttag ttatacaagc
    20461 tggggctatg gctaaaggtg gagaaatatt tgtacttgat atgggagaac ctgtaagaat
    20521 attggattta gcaaaaaact taattaaatt cagtggattt gagccagatg ttgatataaa
    20581 aattgaattt tctggtctta gaccaggaga aaagttgtat gaagaactac ttatgtcaga
    20641 agaaggtctg ttggatacag agcataaaaa gatttttatt ggtagaccaa tagatgttga
    20701 tagagaaaaa ataacaaaat acttaaaact tttaagagaa attactaaca atgaagaggt
    20761 tgaaaaaata gatggtatta tgagggaatt agtgccaact tatattaaac cagaagatgc
    20821 taatatcaaa gaaattgcaa caactagaga aaagtagaat atatttctaa tttgtaacca
    20881 gggggagcaa aaagaaacaa atatatacta aaaagaaaca aaagattaca aaaagattac
    20941 aaaaagatta caaaaaaggt tgcaatttat tttgatgtaa gatagaatgt taattaggaa
    21001 ttggaaacga aggaacaaaa tgttaaattt tcgaaaggat taggtatttg agattatgat
    21061 gaatattaaa aataaaaaac atatattgaa aaaatttata gctatggtgt taatagcagg
    21121 agttgtcaca gtagaagcag gagcaataac ggctagtgca gcagagccaa ctaattcacc
    21181 tatgagtgca acagtagacc agtgtgattt tttaaatgta agaagtggag ctagtgcaaa
    21241 tgatgcagta gtaggaaaga taaacacagg agacaaagtt gaagttttag aattacattc
    21301 aaatggatgg attaaaataa aaagtgttga caatgttaca ggatgggtaa atggagatta
    21361 tttaactatt caaggtggaa atgtagatgc aaaggtacaa aatgttttaa acttagcatt
    21421 taagcaacaa ggtaagccat ataaatgggg agcaactgga ccaaattctt ttgattgttc
    21481 tgggttcact tcttatgtct ataaaaatgg agcaggagtt aatttaccaa gagtatcaag
    21541 atcacaagca acagtaggaa agaaagtatc aagagcagaa ttaaaaccag gagatttagt
    21601 tttctttggt tcaggtggtt caataaatca cgttggattg tatgtaggag attctaaatt
    21661 catacattca ccacaaacag gagatgtagt aaaagttact agcatggctc caggaactaa
    21721 ttatgcaaga agacttataa ctgctacacg tgttttacaa taataataga tattgattta
    21781 cataggattg aatattaaca ttaaatatat aattacattt aatgttttac atagagattt
    21841 aagagtttag taatattaaa atagtgatga acgttataaa aacagcaaag aagataaatt
    21901 tctttgctgt tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgctgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaat
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggatgattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatcgagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg tataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtattagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttga aagtaaaaga tgcttatttt ataggtggta
    23821 atctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactactcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatga
    24241 taaattagaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatgttgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtcg cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ctttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatatata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagtaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 attaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagcatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgcaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggtcagta cttattatgc aaagtttaaa attgtagaag atttgacgaa
    27361 agtagaagga gacatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 tataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgcc ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatagat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaaatcctt tgcatcaaag atttttgatt cctttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagacc ctggactaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatctcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatggttg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agacttgata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actaatcaac aacaaaatgt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttgcaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tatagttata aaattttaaa
    30241 aaataaattt agtataatgt aatgtagtta tttatatgtg attttaactt gcattgattt
    30301 gctatcaatt gtgctttata attagtatat ataaagttta actgtaagat aatttaaaaa
    30361 ataggggaat ttatatgaat aaaaatagca tgacaagaat ttacagttta aataaaataa
    30421 tttttattat aattggaatt ttaggaatag ttttactcac aagacatatt gaggtagata
    30481 ttaaagtttt aattttaatt ttattaacct tgtttagtat aaatgtattt atttcatatc
    30541 ttaaaattaa gttgtatgag gataaaatta atttaggatt gataaataat tcagataagt
    30601 ttataaatat tactaaagat gagaacttcc taaaacatgt tcaaaattat attatcagta
    30661 atgaaaaaga aaactgtgta atggcttgtt ttgatttatg tagactcaaa cttataaatg
    30721 atatatatgg ttatgagcta ggggatgaag tgttaaataa tattttaagt aacttaaaaa
    30781 attattttgg aaaagaagct atttatggaa agttaaaaag tgatgttttt gtattaataa
    30841 taaagcttga aaatagggaa cagaagattc cttatttagt aaatcttatt aagaataaaa
    30901 ttgtgatact aagtcagatt gacagtttta aaatggatat aaatattgag gcttctattg
    30961 gaatttataa atttaacaat aatgaaattg atataaaaaa agctatagat aatgctgata
    31021 tggcaagact taaatcaaaa ggactaaagc acatagagta tgtagaattt gataatgcta
    31081 tggaagaaga aatacaatca attatgaaaa tagagagaga tttattcttg gctattaaaa
    31141 ataaagagtt tgtaattcac tatcaaccta aagttgattc aagtacaggt aacattatag
    31201 gttcagaggc attgataaga tggttgcacc catcattagg catggttgga ccaaataagt
    31261 ttatacctat agctgaaaaa aatggtctga taaacaatat tggtagatgg ctaattcaag
    31321 aagtttttat taccattaac aagtggattt cagaaggtat aaatgtctta ccagtctcaa
    31381 taaatctttc tagagtagaa ctatataaaa atgatttagt tgattttttt aaactgatgt
    31441 ttaatacata taatattcca aaagaactta tagaattaga aattacagaa acgacagcac
    31501 taagagatgt aaaatttata agtgaaaggc tttatgagat taaatcttta ggtatgaata
    31561 tatcattaga tgattttgga gtaggtaatt caaattttat caaccttaag gggataccac
    31621 tagatattat aaaaattgat aggtcactta tattggatat agttacaaat acaaaaacaa
    31681 agtttatggt gaaagcaatt gttaaccttt cacatgattt aaacgtaact gttatatgtg
    31741 aaggggtaga ggatatgcat caggtcaaag tcttaagtga actgggatgt aatttcatac
    31801 aaggttatgt attttttaaa cctttggatg agatgaatta taaaaaactt cttactgacg
    31861 gaagttatat aaatctgaaa gatactcttt tagataaatg catgacagtt gaggaggagt
    31921 aaggatgatt tcagaagatg tagattattc aataagaatc ataagagcta tatttaataa
    31981 tggagaagat aaaccaatag atgctaaaat gatattaaaa agtgaagata taccaatact
    32041 aacactatac agactgctta gaaagctttg tgcaaacaat attcttactt ttaacaaaga
    32101 agatggcaag acatacatgt taaatgtgtc attggataca ataagtctaa gaactattgt
    32161 agaagtaatt gatggaaaaa tatatataaa taaatgtacg agatatgtat ctaattgcag
    32221 taattgctta aaaggttgta aagtaaatcg tgaattgcta gaaatagaaa aagaaattta
    32281 taaactttta tcgagaaaat ctataagaca aatactagaa taaaaaattt tcagctatga
    32341 taataattgg aggttttcgg ttatggatga tatatctcaa gataattttc tactgtctaa
    32401 agagtatgag aatagcttag atgtagatac taaaaaagca agtggaatat attatactcc
    32461 taaaataatt gtagattata ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa
    32521 tccatatcca cgaatacttg atatttcctg tgggtgtgga aattttcttt tagaagtata
    32581 tgatatttta tatgacttat ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga
    32641 aaattattgg actgttgata acatacaccg tcatatatta aactattgta tatatggtgc
    32701 tgatattgat gaaaaagcta taagtatatt aaaagatagc ttaacaaata aaaaggtagt
    32761 aaatgattta gatgaatctg atataaagat taatctattt tgttgtgata gtcttaaaaa
    32821 gaaatggcga tataagtttg attacatagt gggtaatcca ccctatattg gtcataaaaa
    32881 acttgaaaag aaatataaaa aatttctcct agaaaaatat agtgaagttt ataaggataa
    32941 agctgactta tatttttgtt tttataaaaa gattatagat attttaaagc aaggagggat
    33001 tggcagtgtt ataactccaa gatatttttt agaaagtcta tcaggtaaag atttaagaga
    33061 atatattaaa tcaaatgtca atgttcaaga aatagtggat tttttaggtg caaatatatt
    33121 taaaaatata ggggtatcta gttgtattct aacttttgat aagaaaaaaa caaaagagac
    33181 atatatagat gtatttaaaa tcaaaaatga ggatatatgt ataaataaat ttgaaacatt
    33241 ggaagaactt ctaaagagta gcaaatttga acattttaat ataaatcaga gattgctatc
    33301 tgacgaatgg atacttgtaa ataaagatga tgaaactttt tataataaga tacaagaaaa
    33361 atgtaaatat agcttggaag atatagcaat aagttttcaa ggaataatta cagggtgtga
    33421 taaagcgttt attttaagta aagatgatgt aaagttgaac cttgtagatg ataaattttt
    33481 aaaatgttgg ataaaaagta agaatataaa taaatatata gtagataaaa gtgaatatag
    33541 gctaatatac tcaaatgata tagataatga gaatacaaat aaaaggatac tagatgaaat
    33601 tatagggcta tataaaacaa aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa
    33661 atggtatgaa cttcaatggg gtagagaaaa gcttttcttt gaaagaaaaa agataatgta
    33721 tccttataaa tcaaatgaaa atagatttgc tatagattat gataataatt tttcaagtgc
    33781 agatgtatat tcttttttta taaaagaaga gtatttagat aaattttcat atgaatatct
    33841 agttggaatt ttaaattcca gtgtttatga taaatacttt aaaataactg ctaaaaaaat
    33901 gagtaaaaat atatatgatt actatcctaa taaggttatg aagataagga tttttagaga
    33961 taataattat gaagagatag agaatttatc aaagcaaata atatcaattt tattaaataa
    34021 gtctatagat aaaggaaaag tagaaaaatt gcagataaaa atggataact tgataatgga
    34081 ttctttaggt atataagcag ttgtaagtat taaaaaatta taatctttta attgtttatt
    34141 taaatttaga aataaaaagt tagccatata aaaaatatta aaaatatata cttttcaata
    34201 tttttttgat aaaataagaa tgaatttgtg caattttatt tttctccaat aactaaaaat
    34261 agttttttga attaatattt gcttaagaat aaaaatcaga aacgtttttg atatagtagg
    34321 tgataatatg aaaggattag ttttagaagg tggaggaaca aaaggagcct accaaatagg
    34381 tgcatataaa gctttaagag agcttggtat agagtttcaa ggagtaactg gcacatcaat
    34441 tggtgcttta aatggagcat atatagttca aaatgatatt gaagtaatgg aagatatttg
    34501 gttaaattat gactatactc attttatgaa tattgataga gaaacctatg agaggtttaa
    34561 aaatgtagat ttcactacta aaaatctcaa tgcagtgttt gagcttataa ataaagctag
    34621 aaaaaatgaa ggtatagata taagcccatt aagacaacta atggagacaa cattaaatga
    34681 agacataata aggaaatcaa aaaaagactt tggacttgtt acggtctggt gggataaaaa
    34741 aattaatcca tatccattgt atatcgaaga tatacctaaa ggaagattga ttgattattt
    34801 aattgctagt tccagtttgc ctatttttca aacgaacatg atggatgata agttgtatct
    34861 tgatggaatg ttttgtgata acatgccaat aggactcttg gaagacaaag gttatgaaga
    34921 tgttgttgta attaggttga ttgatgattt tattgggaaa atgaatctaa atcgacatca
    34981 aaatataaat ataaaaacta taataccatc agaatatcta ggaggttctc ttaataaaga
    35041 tagagataat gtagaaaaaa acatccgact aggttactta gatactatga aagcatatga
    35101 aagatgcact ggaattaagt attattttga tgtagagtat aaatataatg aagaatattg
    35161 ttttgataaa tttagaagta tgagcaatga aacaatacaa tatatctgta atttattgaa
    35221 tataaaaaga gatgcttcac ttagaaccgt tatggaaagt gtaataccaa agcttggtga
    35281 ggtgcttgga ttgccaaagg atttttcata taaagatttg ttttactgta tatatgaaaa
    35341 gaaacttgaa gaaaataata taaacaggat aaaattatat gattttaaca aggttataga
    35401 tgttgtaaat acaaatattg attctaatag aaatttagct tctaattttg aagttagacc
    35461 taaaattagt attaaaaaga acaaaaacac aaaattattg acaaattgta ttataaaaga
    35521 cataaaaaat caaagttaaa taaaaaacaa aaaaaaattt gtaattatac tcgaaaaaag
    35581 tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg accataggac
    35641 aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt aaaaaatata
    35701 aaatgtaaag tttataggag gatttaaaaa aatggaaaaa gtagttagta tcaaaaatgc
    35761 aagtggatta catgctagac cagcaggaat gtttgttaag aaggcagctg aatttaaatc
    35821 aacagtagag gttgtagcaa aagacaaaac tgtaaatgca aaatcaataa tgggaataat
    35881 gagtttaggt ttagctcaag gagaagaatt aaagttagtt gtaaatggag aagatgaaga
    35941 agtagcttta gctgcaatgg ttgaattagt tgaaagtgga tttggagaat agatataata
    36001 attttttaaa aatttgatat ttagaatcta atattactta aagtaaagta acagagaagt
    36061 attaaacata tacagaccaa catttgtaga tatttaattt ctttgttact ttcatgttta
    36121 tttaatcaga agattaagac tattgttaat tgggtataaa aatataaata ttttagaaaa
    36181 tgaaataaga tatttttaat cataaattca gagtaaaaat acagtaacaa atagtttata
    36241 aaattttata aaaaattata agtaaataaa actataaaaa tgtaaattat ttatataaat
    36301 ttataaagtt tatgtgctag atgatatttt ttaggaggta gggttatggc ttacaaagga
    36361 ataggtgctt ctcctggtgt tgctttaggg aaagcgttag tagttgaaca tagtgaatta
    36421 gtaattgaaa aaaaatctat agataatgtt gaagctgaaa ttgctaaatt agaagatgca
    36481 gttgcagttt ctaaagaaga attagtaaaa gttaaggaaa aggcttctga agaattagga
    36541 gcagaggaag cagaaatatt tgaagcacat ttattagttt tagaagaccc agagttaatt
    36601 ggttctgcaa tagataaaat taaaactgaa agtgtaaatg cagagtatgc tttaaatgaa
    36661 ataaaagaga tgtttgttag catgtttgag tctatggaca atgagtacat gaaagaaaga
    36721 gcggcagata taaaagatgt tacaaataga atacttagac atatattagg aattaaagtt
    36781 gttgatttat ctgctttaag cgaagaagtt gtattaatag cacatgattt aactccatca
    36841 gacacagcaa ctatgaataa aaaaatggtt ttaggatttt taactgatat aggtggaaga
    36901 acttctcata ctgctatcat gtctagaact ttagaaatag ctgcaatcgt tggattaaat
    36961 gatataactt caaaagttaa ggatggagat tttgtggttt tcaatggaga cacaggtgaa
    37021 gtaatcgtga atcctgatga agagactata aataaatata ctgaattaaa agctaagtat
    37081 gaagatgaga gaaaagcatt acagctatta aaaggaaaac catctgtaac tttagacgga
    37141 aaacatgtgg aattagctgg taacatagga acacctaacg atatagaagg tctaataaag
    37201 aatgatgctg aaggtgttgg tctttataga acagaatttt tatacatgga tagagattct
    37261 ttcccaacag aagaaataca atatgaagca tataaagctg tattagaagg aatggatgga
    37321 aagcctatag ttataagaac attggatata ggtggagata aagaattaag ttatttaagt
    37381 atggaacctg aaatgaatcc attcttaggt tacagagcaa taagactttg cctagataga
    37441 aaagatatat ttaagactca attgagagct ttatatagag ctagtgttca tggaagatta
    37501 agaatcatgt tcccaatgat ttcatcttta gaagagttgt tacaagctaa agaagttgta
    37561 aaagaagttt tagcagaact tgattctgaa ggtgtggctt atgctaaaga tgtagaaatt
    37621 ggtatgatga tagaagttcc atctgctgct gtgatatctg atgtattggc taaacacgta
    37681 gatttcttct ctataggaac taatgattta attcaataca cttgtgcagt tgatagaatg
    37741 aatcaaaaga taagctatct ttacaatcaa tttaatccag ctgttttaag acttataaag
    37801 actgttatag acaatgcaca taaagaaggc aaatgggcag gtatgtgtgg agaatctgct
    37861 ggagaccaaa aaatgatacc aatactttta ggtatgggat tagacgagtt ctctatgtct
    37921 ccaatatcaa tacttcctgc tagaaagtta ataacttcag ttaaagagtc agatatgaaa
    37981 aaattagctg atgatgtact taatatgggt actgctgaag aaataaaaag ctatatagaa
    38041 aagactttta atatataatt aatgttatat agttactaaa attcattttt ctaaataaca
    38101 aaattatatt ttacgaatta aaaaggagat gtttcaaaat aaaaatttga agcatctctt
    38161 ttttataaaa gattactaag aattacttaa tctttgtaat agtcattttg tgaaaaagca
    38221 aaactgcatt gtggctatag tatatatgga tgttattatc aataaaagta ctattaaaat
    38281 gaagattcat tctcaaatga tatcaaaagt agttgtgatg gagtaagata atattttgtg
    38341 atttaatagt aaaaattaaa aaaatatggt attgaaaaat aattaaaagt atttaataat
    38401 agaattaggg aagaataagt ttataagtaa aaataattga ttactagtta ataaaataaa
    38461 tgtgatatcc aaataaatcc taaatctaat ttgagtttta atatagatag tctaaagttt
    38521 gattattaaa gatttaattg taagttgtta cagttgatga tattgattag agattaaagt
    38581 ttagagtaga aagttacctt aaatttaaaa atgcaagata acccaatcta aaaattataa
    38641 tcactcaata ggtttaagga tttatttgtt tattataaat aggagggtgt ctcaaaatga
    38701 actttttagt ttatgaggca ctctctttta tatagaatta aatatatttt attatttcaa
    38761 caatgaaaaa gaagcttatc tctattttga gacagcctct ttgtatacta ttattaattt
    38821 aatcaataac ataatttaaa actatattat tagttaagat ttcctgcttt attagtaaat
    38881 aattctttaa tagcattgtt tctggaaact aaatcgttat cagagttgtt tgtttttttc
    38941 ataatcactg aataacgttt tttatttata aaaaatatta aaatcttatc atcatcaaaa
    39001 ttgtattctt tatatctgtc aatagactca taacctagat ttagaatgtt tttgtctttt
    39061 atactatcta catctaaaat atatgatggg tcagccttta gtaatatatt aattaaacat
    39121 ttttcttcac cagcacagaa taactccatc ttacttgata tagatttaga ttgctctgaa
    39181 gttatttttg caggaataag gttgtcattg tcatctctta gaagataacc atgtgtgtct
    39241 tgttgatata ctaaattaac ctttttctta ggaacactaa tcattttatc taaatgtaca
    39301 taatgatgat tttcaacaaa accttcattt aatatttcaa caaagttatt aattttacct
    39361 aggcaaaaag attctataga ttctttacag aatttatttg taaatggtat tatgtttacg
    39421 ttttcctcgt ctgtattcca tgctatagca taatccaacg aatatacttc ttcctctata
    39481 tctgcaaaat tatattgtac tatgtttcct ttcaaaatta ctcgacctcc atcttataat
    39541 atatttaata tactttataa aacttatatt atatttaaat aatatcataa attgaataaa
    39601 tatgatatag taaataagaa aaaatttgaa aaaaatcact ataaatgagt aataaatata
    39661 aatagtgtat actaatggga tggaaaatgt ccactattaa ctttattacc ccacatatat
    39721 aagataaaat tattaatata aaatataatc tatcgacaat gaatagactt ttaaataaac
    39781 ttaatataaa attaattaaa taagtgctta aaaacgattt actttaatga tagaatcata
    39841 ttaaaggagg ataattttat ggatataaag aataaaatta aatctatatt tttaccagaa
    39901 aaaaatgact atttagatga tgaagaattt gagtatgata tagaaaataa tgaagaagat
    39961 ttaaaggaag ataacaaagt acatttaaat gatttaagca gagtaaaata tgattacaga
    40021 gagttaaaag acatagaaaa ccaaacagaa gagatgtgtc tgctagcagt aaagcaggat
    40081 ggtactataa ttgagtttgt aaaggacaag acttataaag tatgtatgga agcagtaaaa
    40141 cagacatata aatctcttaa gtatataaca aatcaaaatg aggatatttg tatagaagca
    40201 gtaaaacaga actacagagc tttgtactac ataaataata agacagaaaa tgtactaatt
    40261 gaggctataa aaaatgcatc aacttatgat gtcatggaag tatttaaatt tgtggaagag
    40321 caaacagaag atgtatgtct agcatttata gaaagggcat ctaaaaatga tgttgcagag
    40381 atattaaaag gaataaaaga gcaaactcca gccatatgtt tagaagctgt aaaaaaagat
    40441 ggaaaatctt tagcttatgt aaaggaacaa agtaatagta tatgtttaga agctgtaaaa
    40501 gaaaactaca gtgcactatc ttgtgtaaaa gagcaaactg aagaaatatg tatagaagca
    40561 gtaaaacaga atgactttgc attgtattat gtaaatgaac agacagaaaa aatatgcatg
    40621 gaagcagtaa aaagaagtta tatggctcta cagtatgtaa ataagcaaac agaagagatt
    40681 tgtttggaag cagtaagaat tgatggaaga gcattacagt acgtaaaaga gcaaacagaa
    40741 gaaatttgct tggagtcagt tagacaaaat ggaaaagtac tgcaatatgt aaaaaaacag
    40801 actgaaaata tatgtataga agcagtaaga ggttcatttg aagaacttga aataaaagaa
    40861 atattaagtt atgtaaagat accaacagaa agaatatttg tagaagcagt aaagcaaaat
    40921 ggaaaaattc ttaaatatgt agaaaatcag acagaattaa tatgtttaga ggcagtaaga
    40981 gaaaactata atgctttagc ttatgtaaag gaacaaacag aaaagatttg tttagaagca
    41041 gttaatcaaa gttatgaagc gcttaaatat gtgaaagaac aaacagaaga agtttgtcta
    41101 aaagcagtaa aacaagatta tagaatgttg aaatatgtaa ataatcaaac agaaaaaata
    41161 tgtttagaag cagtaaagca aaattataga gctttagaat ttgttgataa tcaaacagaa
    41221 aaagtttgtc ttgaagcagt aaaacagaat agaaaagcac tacagtatgt aaaacaaaaa
    41281 caaagttaaa aggctaaaat atatggggaa tatatgcaaa taaataaaat ttgatatttt
    41341 gtaataaata aaatgggtat ctcaaaagga actttttagt ttgtgaggta ctctttttat
    41401 atgaaatgaa atatattttt agccttttaa caaaggggaa aaggtttgtt tctattttga
    41461 cataggcttt ttatgcatat aaagcttgat aaaattgttt tattataatt gttttgttat
    41521 ataaataata agaagaaaat tatataggtc tttttttgac cagttttaca tttttaacaa
    41581 ctagttttgt aaagtatatt gaattttctc aaaaaagaat gtactctata tatgtaaaat
    41641 ttttttggag gtaaaaatgt ttaaaagata tgctgaaaaa atgacatctg ttttaatttg
    41701 taataatatg atagataata atgaatctaa agtctattct tatggatttg aaatattaat
    41761 agctttcata gttaatataa ccaccatgct gtttataggt tttttatttg gtaaatttac
    41821 atatgtatta ttttttttaa tgtgttattg tccaataaga caattttcag gagggtatca
    41881 tgcagacaat tattttagat gcttattaac ttttattttt ataattttat ccacaatctt
    41941 aattatagaa aatataaata tagacttatt taaaaatatt attatgatta ttgcaagtgt
    42001 tagttgggtt ggaatttgtg ttctgtgccc aatagaacat aggagtaacc ctataagtga
    42061 tagggaaaag ttggtttata agaaaactgc tatatttata tctacagtag tgttattgat
    42121 aacaatttca agtctttctt tgagtatatt tgtagattat ttcacatata gcgcatttgc
    42181 catgttttgg atttttgtga tgttagtatt aggtaagtta aaagctaaag tataagtaaa
    42241 atatgtatga gggagagtta agttatgaaa aagtttattg taagatttat gaagtttgct
    42301 agctcattgg cacttagcac tgctattttg tcagctaata gtacctgtcc ttggattatt
    42361 catcagccta aagtacccaa agaaatcagc aatctaaaga agacaaatta aatacaagca
    42421 cttatttata caaaattatc aggaaaaaag aaattattat attttaataa gattaaaaca
    42481 atataaaatc agatacaaaa tttattttat aggagcctaa tacctatttg gtaatatatt
    42541 agtgcgccaa tttaggggga tatagtgtat ttaatgaaat gacttacgga gagtaagtca
    42601 tttttgtatt gtatgtattt tatgtaaact tatgatataa tgaagggtaa agtttaatta
    42661 aaataataaa aaactttagt atagatagta atttaggagg tagggtatga gtatgataca
    42721 taaattttct atgaatggat ataatatcgt tttagatgtg aatggtggag ctgttcatgt
    42781 gttagatgat gttgcatacg atttgttaga tttttataaa gaaaaaagta aagaagaaat
    42841 attagagata ttaaaatcaa aatatcaaga agaaaaaata aatgaagcat atgaagaaat
    42901 attaaatttg gaaaaagagg gtcttttata tacagaagat acatatcaat atcatccaag
    42961 ctttgtacat agagagcctg tagtaaaagc tttatgttta aatgtagctc atgattgtaa
    43021 cttaaaatgt aaatactgtt ttgcagctca aggtgatttt ggaggagaaa aagaacttat
    43081 gagttttgaa gttggtaagg cagcaattga ctatttgatt gctaattcag gaagtagaaa
    43141 gaacctagag atagatttct ttggtggaga gcctttgatg aactttgaag ttgtaaaaca
    43201 actggttgac tatggaagaa gtgtagaaaa agattataat aaaaatataa gatttacaat
    43261 aactacaaat ggtgtactgc taaatgatga gattatagat tatataaatg aaaatatgca
    43321 taatgtagtt ttaagtttag atggaagaaa agaagttaat gataatatga gaccaacttt
    43381 aaatgataaa ggaagttatg atattacatt accacgattt aagaaacttg tggaaaaaag
    43441 agcaaaagat aagtattatt atataagagg tacttttaca agagataatt tagatttttc
    43501 aaaagatgtt atgcattttg cagatttagg atttaaatta acctctgtag agccagtcgt
    43561 tggagatgag agtaatccat atgcacttag agaagaagat ttacctaaga tatttgaaga
    43621 gtacgaaaaa tttgctgtag agtatgcaga tagacaatta caaggagatg gatttaaatt
    43681 tttccatttt atgatagacc taaatcaagg tccatgtgta ataaagagaa taactggatg
    43741 tggagctgga aatgagtatc tttctgtaac tccaaatgga gatatctatc catgtcatca
    43801 atttgttgga aatgaagaat ttaaaatggc aaatatattt gatgaagaaa tagtacttcc
    43861 agaaaattta aaaaatatgt ttagagaagc tcatgtatat actaaagaag agtgtaaaca
    43921 atgttggaat aagttttact gttcaggtgg atgtcatgca aatgcgataa actttaataa
    43981 tgacatatca aaaccatatg aattaggatg tgaaatgcaa agaaaacgta cagagtgctc
    44041 tataatgata caagctaagt taatgttaga aggagcaacc aactaaattt atattttaaa
    44101 ggagttgttt atatatgatt agagattatt tagaagataa acctttaatt gacgaaagtg
    44161 tatttgtggc aaaatcagca gatgtaattg gaaatgttaa aataggcaaa gattcaagta
    44221 tatggtacaa tgcagtagtt aggggtgatg aaggaccaat aactattgga gaaaacacta
    44281 atatacaaga ttgttctata gtgcatggag atacagaaac tataattggt aacaatgtaa
    44341 cagttgggca taggtctata gttcatggtt gtaaaattag tgataatgtg ttaattggta
    44401 tgggttcaat aatattggat aatgctgaaa taggagaata tactctgata ggagcaggta
    44461 cactaattac atctaataag aagtttccgc caggtgtttt gataatgggt tctcctggta
    44521 aggttgttag agagcttaca gaagaagata aaaaatatat tgatgaatct tatgaatggt
    44581 atttagaggc agcacaaaat caaaaatatt agtttaaaga gtggttgttt caaaacatat
    44641 ttaaatctgt tttgaggcaa ccactaattt attttattag attttgttga tattttagtt
    44701 ttcaaaaagt atttgattaa accagatata aaatgtcaaa aataaaaatt aactgagtta
    44761 aataatttta ataaaattgg tagtatatgt gataaaatta aatattaaag aggatatagg
    44821 atattagaat atcaattggt gaaataatgt catatacgat aaattaaggt gtaagttttt
    44881 gggtatacct atcttaggag tgaaaagatt tgagaataag ttatagaaat ttaaagcgat
    44941 atagagaaat tggatatgtt ttaataaagt atggttttag ttttattgta gaaagactaa
    45001 atatagaagg aattgcctat aaaataccac tatttgaccc accagaagaa ataaaaaata
    45061 tgacaactgg tgagagaatg aaaagagttt tagaagaact aggacctaca tatataaaaa
    45121 taggacagat attgagtaca agaaaagact tgttagacca ggatataatt gatgaaatat
    45181 caaaactcag agatgatgta gagaaatttg attcaaatat agctattgat atatttaaag
    45241 aagaagtggg tttaagtata gaagaaatat tcttagaatt taaagaagaa gcaatagcag
    45301 cagcttcaat tggtcaagtt tatgaaggtg tacttaaaac gggagaagaa gtaatcgtaa
    45361 aaattcaaag accaaatata gagaaaataa taaaatctga tttagagatt cttagaacta
    45421 ttgcaaatac tttaaaagat ttaaaaaagg attttaattt agatttagta cagatgattg
    45481 aagaatttca aactcaatta atgagggaac ttgattatac atttgaagct ataaatgcaa
    45541 ctaaattctc taggatattt aaaaatagtg atgaagtata tatacctaaa gtatattcag
    45601 aatataatac taagaaaatt ttagtaatgg agaaagttaa tggtacaaag ttaagtgatg
    45661 tagaaaaaat aaggagacta ggttataaca caaaaactat tgttgaaata ggcgttaggt
    45721 cattttttac acaggtatta tctcatggat tttttcatgc agacccacat ccaggtaata
    45781 tattcgtagt tgctaaaaat aagatagcat atatagattt tggaatgatt ggaattattg
    45841 ataataaaac tttaaaccaa ttaaatgaaa ttgcattagc aggtgtagaa aagaatgttg
    45901 acaagataat atatctattg atagaaatgg atgcattaaa tggagaggct gatattaagg
    45961 gacttagaca ggatttactt tatctaatac attattacta tgatatttct atagaaaaaa
    46021 taaatgtaac agatatatta aatgaactat ttaggttttt tagacagtat aaaatagtca
    46081 tgcctgcaca atttgtaact cttgcaaaga cagttataac attagaagga acaagtagaa
    46141 ctttaaacac agatttttct tttggttcta tgggaaaaga gtttatgaaa catcattata
    46201 agagtaaatt taaccctaaa aatgttgttt taagttcaag acaaaatgta gaagaaatat
    46261 tactggacat aaaaactatt ccaaagcaat taaaagcaat tttaaaaaat atagaaagaa
    46321 ataatataaa aatgcaaatt gaagatgtta aaatgacgag gttagaaaat tgtataatag
    46381 agctaacatc tcaaatatct ttgagtttag tgttggcatc tattatagta ggttcttctc
    46441 ttataattgc atctccaaat atagaaaata atatatggat aaaatttact gcaatagcgg
    46501 gtttctttat atcctttata ataggccttt gcttagttat aagaagtatt aggtcaaaat
    46561 acaaaaaaga ttagggggaa ttaaatttga aaaaatggat attgaagtat aaaggtaaga
    46621 tagaggaaag tgaatttagc aaaaaactta atatttcccc ggaaatctgc caaattttaa
    46681 aaaatagagg gatatgtact gaaaaagatt cagagatatt tatgaatcca tctttagatt
    46741 atttaagaga ccctttttta atgaaagata tgcaaaaagc tgttgataga ataaagttag
    46801 cagttgagaa gaacgaaaaa atttggattt acggagatta tgatgttgat ggtgtatcat
    46861 ctacatctat cttgtgctta tattttaaga gtataggtta caatgttgat tactatattc
    46921 ctaatagatt agaagaaggg tatggtataa atgaagatgc tattaagctt ataagctcta
    46981 ggggatgtga cttgattata agtgttgact gtggaattac atcagtgtct gaggtcaata
    47041 cagcgaatga tttgggcata gatgttataa ttacagacca tcatgaatgt caaagtgaaa
    47101 ttccatcagc ctttgcagta ataaatccaa aacaagaaga ttgtaattat ccatttgatt
    47161 cactatgtgg atgtggtgta gcatttaaaa tgattcaagc cttgactcca aaagaagaat
    47221 ttaaaactag tatgtataat tatttggaaa tagtaacact agcaactatt tgtgatattg
    47281 ttccacttat agatgaaaat agaataattg taaaaaatgg tttaaaatca atgaaagaag
    47341 gcaaaaatat tggattaagg gagcttataa aagtttgtgg tgtagaaagt gataagatag
    47401 gttcttctca tataggtttt gcaataggtc ctaggataaa tgcttcaggt cgattgggat
    47461 attcttactt aggagtagag ctatttacta ctcaatcaca agaagaggca gtagaaatag
    47521 ctagtatatt ggaagaaaaa aataatgaaa gacagatgat agaagctaag atgtatcatg
    47581 aagctgagga aatgctaaag tctaatagca gatacaatga tgacaaggtg ttggttttag
    47641 ctaaagaggg ttggcaacat ggaataatag gaattgtagc atcaaagtta actgaaaaat
    47701 actacaaacc aacaattctt ctaggtatag aaaatgggga ggctactggt tcagcgaggt
    47761 caataaaagg atttaatata tttgaagctc tcataaagtg caaagacttg atgactaagt
    47821 ttggtggtca tgaacaagca gcagggttat ccttggattc agacaatgta gaaattttag
    47881 caaatgaaat aaataaattt gcagattata atttaactga agatgatatg atagagaatg
    47941 taaatgttga gtttgaatta caagaaaatg taataaattt aaatcttgta gaagaattac
    48001 ataagttaga accctttgga ttaaataatc ctaatcctag atttatagtt agaaattata
    48061 ttttaaaaga tttgaaagtt ataggtaaga atcaacaaca tctgaaatta agcatagaaa
    48121 aagagaaaag ctatgaatgt ataggattta atatgagtca tttaaaatca atgtataaag
    48181 taggagacaa ggtagatgta ctattccaat tagatgaaaa taactatatg ggaaatagga
    48241 aagtacaatt tttacttaaa gatatacgat tggctcgacc taaaagtgca agtaatgaca
    48301 aactttcatt gaaattaatg tcaaaaataa taccaaaaga tactcaaagc ctgtataata
    48361 tatctgtgtc tgattttgaa ttatttgatg gaaatacaga tataaatata tttgattatt
    48421 ttgaaaaaga tacactaata atatctaatt ctataaatgg attttataga gcaatgtcag
    48481 atatatcact tatagatttg gattttaaca taaattacaa tattattgaa gatgttagca
    48541 aaaatactga taaattagag cttatatttt ctcctaatat tgataaaata gacttaaaaa
    48601 gatataataa tattattctt tatgattatt tatacaataa aggcgaatat tcgtatatat
    48661 atgagaataa aagagaagaa agtgaaatta taaaatatta taataaaaca gacctattat
    48721 atttaaagaa tgtagttagt aatatagttc catcaagaga tgaatttata acaatttata
    48781 aacaagcact cataaaaaaa gaaattgatt tggatatggt aaatataagg gaaactttta
    48841 atgtaattcc attaaagttt tttacgatat taaatgtatt tagagaatta aatttacttg
    48901 actttaattt aaattatgaa aaaaattctg tactcataag aatattgcca aaaccacaga
    48961 aaaaattaga cttaaatgag agtttaatac tcaataatct aaaaaattta gaaaaacaat
    49021 acaatagcag ttattaggag gcgtttccca tggatttaaa aaactttata aggaatattg
    49081 atgatttccc aaagccaggc atagatttta aagatgtgac aactctattt aaagatggag
    49141 atgcatttaa atatgcagtg gattctatag ttgaagaatt gaaagataaa gatgtagatt
    49201 tagtaatagg accagaagca agaggatttt tgatgggtac acctgtagca tatgctttag
    49261 gagtaggatt tgttccaatt agaaaacctg gaaagttacc aggtgaagtt gagagttatg
    49321 agtatggatt agagtatggt acagatactt tagagataca taaggatgca attaaaaagg
    49381 gtcaaaaagt agcaatagta gatgatttat tggctactgg tggaactatg gaagccgctg
    49441 ccaagcttgt agaaaaatta ggtggagaag tagtttctat gcaatttttg attgagctaa
    49501 aattcttaaa tgggagagaa aagttgtcta actatgatgt taattctctt ataaaatact
    49561 agtactttta taatagttgg tataacacca actattttca tatatattaa aattttatac
    49621 aaaataggtg gttatatgca tgataaagaa ttacaagaaa taattgaaaa aataaaagtt
    49681 tatgcaccta atgcaaattt tgaaatggtt gaaaaagcct ataatcttgc aaaaaaagcg
    49741 catgaaggac aatatagaaa atctggggaa ccatacttta ttcatccatt agcagttgca
    49801 aatattttaa tagagatgga attagatatt gaaactataa cagcaggttt acttcatgat
    49861 gttgtagaag atacagaata tacctatgaa gacataaaaa aagaatttgg caaagaagta
    49921 gcggatttgg ttgatggagt aactaaactt ggtcaaataa aatatcgttc gaaagaagaa
    49981 actcaatctg aaaatttaag aaaaatgttt ttggcaatgg cgaaggatat aagggttata
    50041 cttataaaac ttgctgatag attgcacaac atgagaacat taaaatacat gcctccagaa
    50101 aaagcaaagt ataaagcaaa agagacactt gaaatttatg gtggtatagc tcatagatta
    50161 ggaatttcca agataaagtg ggaactagaa gacagagcat taagatttat ggacccagaa
    50221 gggtattatg atttagttag tagagtatca atgaagagaa gtcaaagaga ggattatatt
    50281 caaggaattg ttgaacttct taaagataag tttaaagatt taagtatacc atgtgatgta
    50341 tatggtagac caaagcattt ttacagtata tatagaaaga tgcaaaaaaa acataagact
    50401 tttgaagaga tttttgattt aacagcagta aggatattgg ttgataatgt aaaggattgc
    50461 tatgcagtac ttggtatagt tcatacatta tggagaccta ttccaggaag atttaaagat
    50521 tatatagcaa tgccaaaacc caatatgtat caatcattac acaccactgt tgtaggtcct
    50581 gatggagaac ctttagagat acaaataaga actcatgaga tgcataatat agctgaaaat
    50641 ggtatagcag cccattggaa atataaagaa ggtatctcta gcaaagaatc aaaggttgaa
    50701 gaaaaacttc aatggttgag acagatgatg gagtgggaaa aagatttaaa agacccacaa
    50761 gagtttatgg atgcacttaa agaagatgta tttaatagtc aagtttatgt atttacgcca
    50821 aaaggagacg taattgaatt accagcagaa tcaacaccta tagattttgc ctatagggtt
    50881 catacaaatg taggcaataa atgtgtagga gctaaaattg atggaagaat agttcctatt
    50941 gattataagc ttcaaaatgg taatattgtc gaggtactta catcatctaa ttctaatgga
    51001 ccaagtaggg attggcttaa tatagtgaag accccaaatg caaaaagtag aattagacaa
    51061 tttttcaaga aggaaagaag agaagaaaat gttgaccgtg gaaatacaat attagaaaga
    51121 gaatttaaga agcatgatat accacaaaaa gaccctcttg ttgaaaaata tatggcatta
    51181 gttgctaaga aatttaatca gccaagtgtt gaggacttaa ttgccactgt aggttatggt
    51241 ggtataatgt catctcaagt ggtatctaag gtaaaagacc tatatttaaa agaggttaaa
    51301 aaagctaaaa aggaacaaca gatacaagaa gaagatttaa ataaacacaa tataagtgaa
    51361 acagaataca gtaaaaagag aaagaaaaac gcatcacaag gaattatagt aaaagggctt
    51421 gacaatatct tagtaagatt tgctaagtgt tgtaatcctc ttccaggaga tgaaattgta
    51481 ggatatatta ctaagggtag gggagtagcc atacacagag ctgattgccc aaatgcaaac
    51541 aataatggtg atttcttcca aaatagattg gtggaggttt catggagttc agcaggaaaa
    51601 ggtaagtttg aagcggaaat tcaaataaaa gctattgata gaagaggaat tgttaatgaa
    51661 ataactcata ttgttgcaat ggataaactt agtttaaacg gaataaatgc aagaaaaggt
    51721 aaggatagta ttgtaagtat aaacttactt gtagaggtta atgacacaga ggaattaaaa
    51781 attctaatga aaaaattaaa agcaattcct ggtgtagaaa gtatttatag aatgacaaat
    51841 tagagttaaa ataataggga ggaaactatg agagcagtag tgcaaagagt atcttcatct
    51901 aaagttacag tagatgaaaa cactataggt caaataaata aggggttact agtattgtta
    51961 ggagtgactc atgatgataa atcaagtgat gtagattata tgattgataa aatattgaat
    52021 ctgagaattt ttgaagatga aaatgacaag atgaatttat ctctaatgga tataggtgga
    52081 gagcttttag tagtatctca atttacttta tatggagatt gcagaaaagg aagaagacct
    52141 ggatttagta atgcagctag gccagaactt gcaaataacc tttatgaaga atttgtaaaa
    52201 aaagcaaaag ataaaggtgt gacagttggt acaggtcaat ttgcagctca tatgatggta
    52261 gagttaacta atgatggtcc agtaacaata ctattagact caagtaaatc tttttaaggg
    52321 ggaaaacttt aatgattata aaaaaatttg tagatagtta ttttggagta aatacttatg
    52381 tattaggtga tgaaaagact aaaaaatgtg cagttataga cccaggtgga agtttagtag
    52441 agacattaag ttttgtaaaa gaaaatgaat taaatattga atatattatc cttactcatg
    52501 ggcatggaga ccatatagga tatgttaagg atattaaaga aaaaactggt gctaaagtag
    52561 ttgcacatgt tgatgaaaaa gaattattaa atgacaaaaa taaaaatcta agttatacaa
    52621 tgagatgtgg agcgcaagag tttgatgcag atatctatgt aaatgataaa gacaagcttg
    52681 aacttggtga attaaaaatg actttcttgc atactccagg acatactcaa ggatgtatgt
    52741 gtataagagt tgaagatgaa atgttcacag gagatacttt gtttgctgga agtattggta
    52801 gaactgattt atatagtgga gactttaacc aaatggaaaa atcacttaag aaattatgta
    52861 aatatgaaga tgctgttaga gtatatcctg gacatggacc aaccagtact ctaggggttg
    52921 aaaagaagac aaatccttac atgtaatttt atattagtat ttaaaaaagt ataaaatatt
    52981 taataactat attagtgagg gggttcttct actgttaaat agaaggagtt aagttgatgt
    53041 tgtatgtttt tttaaaagga catgattata agtatgaagt agcagaactt ataaaattgt
    53101 ttactagtga atttaagttt aaagactcta atgctaacaa taatatagag tcaaagcatt
    53161 taataaatag attgatttat gagaatggtg tattattctc aagtactgaa tactatgaaa
    53221 atggaaactt aaagtacgag tcaatacaga atatagaaaa tatgaatctt gaatttttag
    53281 atggatttga tagcagcaaa acgattgaag aatttcttaa tagcctagat agtgaaagta
    53341 agaggaactt taaaaagctg tgtaaagaaa atatcaaaaa aagcatgttt ttagtgctta
    53401 aacaagtatt taattcttat gtaccatggg gaattttgac tggtattaga ccagtcaaaa
    53461 ttgtccacaa tttaatggat aaaaagctag atgataatag cataagaacc attctaaaag
    53521 ataattattt tataatagat gagaaaatag atttagctct tgaaatagct aaaagagagc
    53581 gattatttat gtatcctata gataaaaata aaatttctct ttatgtaagt attccatttt
    53641 gtccaactag atgtgtatat tgttcatttc cttcaaattc attaaaacaa tttggacatt
    53701 taaaaagaga atatgtttat aaattgattg aagaaattaa ggggtttgcc aaagttatta
    53761 aggatactaa gaaagaagtt gaaactctat atattggtgg tggaactcca actacacttg
    53821 atgaggaaga attggatttg cttataaatt cattgttcaa tgaattagat ttaagtaaaa
    53881 ttaaagaatt tactgtagaa gcaggtagac ctgacactat tacagaacaa aaactaagag
    53941 tgttaaaaaa acacaatgtt agtagaatta gtataaatcc tcaaactatg aatgatgata
    54001 ccttggtaaa gattggaaga gagcatagag tatctgattt agtagattgc tttaatatgg
    54061 ctcgtagaat gggatttgat aatataaata tggatataat tttaggtctt atagatgaag
    54121 acttaaatat ggtaaagaac acattggagg agataaaaaa actttctcct gaaagcctta
    54181 cagttcatac attagccata aagagagcat ctaacttaaa tataaatatg gataggtata
    54241 aagaacatct aacacaatat gaagaaatgg taaaaatgat agatttatca atgaaatatg
    54301 caaaagatat gggattaaat ccatattata tgtacagaca aaaacatatg ttgggaaatt
    54361 tagaaaatat aggttatgct aaagaaggat atgagtgcat ttataatata cagattatgg
    54421 aagaaaaaca aagtaactat gcattaggtg caggtgctat atcgaaattt gtctatgtag
    54481 atgaagatag aattgaaaga gtagaaaatg taaaaaatgt tgaacaatac attgaaagag
    54541 tagatgaaat gataaaaagg aagaaagaag aggtatataa aaatgttgac taaagctcct
    54601 agaggaacta aagacataac tccaaaagag gcttacaaat ggcgttatgt agaaaataaa
    54661 tttagagaaa tatgtgcttt atatggatat gaagaaatgg taacacctat atttgaacat
    54721 acagaacttt tcaagagaag tgttggagat actacagata tagttcaaaa agaaatgtat
    54781 tcttttaaag ataaaggtga tagagaaatt accctaaagc cagaaggtac agcaggtgta
    54841 gtaagagcat ttatagaaaa taaattatat gcagatactc aaccaacaaa attattttat
    54901 gtgacacctt gttttagata tgaaagacca caagctggta gacaaagaca atttcaccaa
    54961 tttggaatag aagcacttgg aagtgatact ccttcaatgg atgctgaaat aatcgcacta
    55021 gctgttcaat tttttaatga agttggatta aatgatttgg tagtgagtat aaattcagtt
    55081 ggctgtccag tttgtagaaa agagtacaat gctttattaa aagagtatct tgactcaaaa
    55141 gctgatatat tgtgtgatac ttgcaatgag agaagagaaa aaaatccaat gagggttata
    55201 gactgtaaaa atcctacatg taaagaaaat atcaaagata taccatttat tgcagaccat
    55261 ttgtgtgatg attgtaaatc tcactttgat aaacttcaag aatacttaaa ggaaatgaat
    55321 ataaactttg taattgataa aacaatagtt agaggcttag attactatag aaaaactgct
    55381 tttgaaatta tatctaatga tataggagct caaagtactg tatgtggtgg aggaagatat
    55441 gatggtcttg ttgaacaatt aggaggacca aaaggtataa gtggaattgg gtttggacta
    55501 ggaattgaaa gacttttact tacacttgaa ggtaatggaa ttgaaataga aaaccctcaa
    55561 tctacggata tatttatagt aactataggt gaagaagcaa atacaagaag ctttaaattg
    55621 ttaaaagact tgagacaaaa tcatataagt gcagataaag accatataga gagaagtgtt
    55681 aaagcacaat ttaaatattc agataaaata aattcaaaat ttacaatagt aattggagat
    55741 gatgaactta aaaatgacac tgcgacatta aaaaatatga aaacatcaga gcaaactact
    55801 gtaaaattaa gtacattagt tgaagaatta aagcaaaagc tgtaaaataa gaaagtatga
    55861 tgttttgtgt attagataaa tatatagcat taaaattaaa taaaatggag gtagtatctt
    55921 ggaaacttta aagggtttaa agagaactca ctactgtgga gagttgagag aaaaaaacat
    55981 aaatgaagaa gtcgtactta tgggatgggt acagaaaaaa agaaatttag gtggtcttgt
    56041 atttgttgat ttaagagata caagtggatt atgtcaaata gtttttgata cagatgtaga
    56101 taaagaagct tttgaaaaag ctgaaaaatt aggggctgaa tttgtaatag ctgtaaaagg
    56161 aaaagtatgc gaaagacaat ctaaaaaccc taatatgcca actggtgata tagaaatatt
    56221 tgcaactgaa cttagacttt taaacaagtc agaaactccg cctatttata taaaagatga
    56281 tgatgatgtt tctgaagcac taagattaaa atatagatac ttagatttaa gaaaaccatc
    56341 tatgcaaaga aatttaaaat taagacataa agtaatgaat attacaagaa attacttatc
    56401 aaacaataga ttttgcgaaa tagaaacacc atttttaata gctccaacac cagaaggagc
    56461 aagagattat ctagtaccaa gtagagttaa tccaggaaaa ttttacgcat taccacaatc
    56521 accacaatta tataaacaat tattgatggt aagtggtatg gatagatatt tccaaatagt
    56581 taaatgcttt agagatgaag acttaagagc agatagacaa ccagagttta cacaaataga
    56641 ctgcgaaatg tcttttgttg agcaagaaga tgttatgagt atgattgaag gtttgcttga
    56701 agcgatattt aaagaagttt tagatgtaga attggcactt ccacttccta agatgactta
    56761 tgcagaagct atgtctaaat atggttcaga taaaccagat actagatttg ggtatgagtt
    56821 aacagatata tctgatgttg tttgtaactg tggatttaaa gtgtttgctg atgctacaca
    56881 accaggaaaa agtgttagag gtataaacgt aaaaggcaaa gctgacgact ttactagaaa
    56941 acaaatatca tcactagaag aacatgctaa gacatataga gcaaaaggtc ttgcttggat
    57001 gaaagtagga caagaaggag taacttctcc aatagcaaaa ttcttcaatg aagaagaaat
    57061 gaacgctata cttacaagaa tgaatgctga agtaggagat ttacttttat ttgtagctga
    57121 taaaaactca atagtatttg atgctttagg acaagttaga cttgaagtag caaataggct
    57181 taatctattg gataaaaatg tatataactt actatgggta actgagttcc cagtttttga
    57241 agaagatgaa gaaacaggca cattctcagc aatgcatcac ccatttacat cacctatgga
    57301 tgaagattta gacaagttag aagaaggtga taagtcatct ttaagagcga aagcttatga
    57361 tattgtattg aatggttatg aaataggtgg aggaagtgtt agaatatcaa attctgatgt
    57421 tcaatcaaga atgtttaaag cacttggttt tacagaggaa agagctaatg aaaagtttgg
    57481 ttatttatta gaagcattta aatatggtac tcctcctcat gctggtctag cttttggtct
    57541 tgatagactt gttatgttac ttgcaggaac tgataatata agagaagtta ttgcattccc
    57601 taaaaatcaa aatgctgttt gccctatgac aaatgctcct acattggcgg aagatgagca
    57661 attagaagaa ttaagtataa aagttgatat aaaagataat gaataatatg tagttgcaag
    57721 aaactaaaat gtaaaaagtc tggatataaa atatatttat attcagactt tttttattag
    57781 aattatttta tattttttct ctatatattt tcataaatta tacttatatt cttaaccaat
    57841 ataattaaaa tactatgttt aaaaatttta cataaacttg gttgttttag aaactacttc
    57901 tgtaacgagt acacgatttt aattaaagaa tatataacaa atttgaaata agtctaatat
    57961 atgacttaat agattaaatt aaaataataa atttggacta tttatctatt tataacttaa
    58021 attatatcaa attgataaca aactagatat tatacttttt tgtagaatag aattacaatt
    58081 atataaagaa aaattctatt aatagtgaaa aaaaagtaga aaaaagtaga aattattctt
    58141 ttataaagaa agggagggat aatattgcaa gagagagaag aattagtttt aaatccagtt
    58201 ccaaaagagg aaagagttgg atggttagct ccattgttta atatgcttgg ttctaacata
    58261 gctatatctg aactaatggt tgggggaact ttaattttag gaatgactct ttctaatatg
    58321 attattacat caattatagg gaacttaata ttagttgcaa ttattatgat acaaggttat
    58381 ataggttaca aagaagggtt aaatacgtat gtattagcta agggggcatt tggagagata
    58441 ggaggaaagt atcttatatc tctattactt ggtataacta gttttggatg gtttggtgta
    58501 caagcagggg ttgcaggact atcagtacaa aagatattcc caagtgtaaa cctaacatta
    58561 gttacagtta tacttggatt atttatggtt gtttttgcac tgtatggttt taaagctatg
    58621 gctaaattta attacttagt tataccacca cttatgatat taatggtgtg gggagttttt
    58681 aaagcttttt ctacttatgg agttgaagct atttataatt atactcctca aacaactatg
    58741 agtatggttg aaggtcttaa tattgtagta ggtcttgtta tagttggtgc aattatatca
    58801 cctgaccagt taagatatac gagacgagta aaagacattt ggattatcag ttttttaggt
    58861 ctagggatta tttcattatt ccaacaagtt gcagctggtg taatgtctat gggagcacct
    58921 acttgggata taacagaagt attggctaat ttaggttttg gatgggtagc gtttgttatt
    58981 ttaatacttg catcttggtc tacaaacgta tcaaatgctt attctggtgg attagcatta
    59041 aaaactattt ttccaaatgt aaaaagaaat gttttgactt tagttgcagg tctaataggt
    59101 acaataatag cagctactgg tataatattt aaatttcagt catttttatc tttcttggga
    59161 atcgcagttc ctgcaatagc aggaattatg tggtgtgagt attattttat acaaggaaga
    59221 acttataagc atagagaagg aataaattgg attgcagtaa taagttggtt aataggtttt
    59281 gcagcgtcgt attatagttc aaaaataaat ttcttaatac ctccgataaa tggaattgta
    59341 gtgagtatgg ttatttatta tatattaatg aattgttttg gaatcaaaga taaataaagg
    59401 gggcaattac atgggtcgta aggtgaaaat aggtataatt caacaacaca gtgtacttgg
    59461 aaatgttaaa aaaaatatag aaaaagcagt agagatgata gatgacttag gaaaacaagg
    59521 ggcagatata atttgtttac cagaactatt tgctacagga tataatttag agtctttagg
    59581 tggagttaaa acattagaat taataagaga acataataag tacatagagg aatcaatgtc
    59641 agaagctgct aaaagaaata atgtatacct gatatctcca tatggaacct tagaaaaagg
    59701 gtctacacat gtttataatt cagcagttat atttgataga aaaggtaaga ttatgggaga
    59761 atactgtaaa aatcatctgt ggtcattaga agcagtatac tttaaaggag gggaaaaagt
    59821 agaggtatat gatgctgatt ttggtagatt tggtgtaatg atatgttatg atgcaggttt
    59881 tccagaagta tccagagaat tgacattaaa aggttctgaa ataatattta taccatctgc
    59941 atggagaata caagatgaag atatgtggga tttaaatgta tctcaaagag ctttagagaa
    60001 cactgtatat acagtaggtg taaatttagt aagtaatgac tctaatttaa tactatttgg
    60061 aaagagtaaa atatgcaatc ctagaggtac tgtaataact caattagata catacaggga
    60121 aaaatatgta ttatcagaga ttgatttaga tgaaataaaa aagtataggg aagatatccc
    60181 ctatttgaaa gacagaaaaa gtagctataa catataattc tatactataa tacaagttca
    60241 atataaaatg ataaaaagag gatgtatcaa tattaagatt aaatttatta tactttgata
    60301 tatcctcttt aatattatca actttgattt aaatattttt aaaatagttg ataagaaagt
    60361 ttttgaacaa caacacagct ttagattcat agttttcgct aaaccatgaa agatttaaat
    60421 atcttttaaa ttcaatatct ttgatatgta acaacttaat ctcagggtct tgagataatc
    60481 cccatgattt tccacatata aatccaactc cttgaagtga ttttataaga gcataaattg
    60541 tatatggtga atcagactca aatgctattt tgggtttgaa attagctgat tcgcacagga
    60601 tatcaattac ctctctataa ttctcaccct tcgttataac tataaagttt tcatctgaaa
    60661 cttcgcttag atatacttca tcctttaatg ataaaggatg gtttattgaa actcctaata
    60721 gtatttcttc gcatgttaaa gttatgctat tttctgagtt tagctttgta aatgaagaag
    60781 atatgtacaa atcaaaatca ctttttttat aagatgatgg caaagtatgt gacacattaa
    60841 aagtaatatt gggatatagt tttctgaaat tactcaaaag tgatggtaac acattagccg
    60901 ctgcaggaga taatatcttt acttctcctg aattttccaa agaagtgtct tgtaactcct
    60961 tttttgaact ttctactaaa tctaaaatgc tatctactct ttttagaaac aatcttccat
    61021 actcatttaa aacaatatat cttccttttc tgtcaaataa ctgaactcca agttcttttt
    61081 ctaaggaaga tatagttttg cttaaagctg gctgtgctat atttaacttg tgtgatgctt
    61141 ttgttatgtg ctccattcta gcaacagttt gaaaatactt aagatgcaat aaatccatag
    61201 tataaaatac acctctttta atatgacttg agttatatca attttataat caactccaca
    61261 ttatacatta taatataaag tttatataat aaactacaat atattaaaaa gttatttaaa
    61321 ttgttattta tattttgtac ataatctaat taaaaaaagt aactttaaat ggttaactaa
    61381 ggaaatattg ttacaaactt tagttatata aaaaattcgt ttgatgagca aagtattaat
    61441 gtcaagtaag aataaaagct tattagataa gaaaaataat attttataat aatgatgtta
    61501 cttaaattat tatgttatac tattttaaat aggaaacatt tagatactat aattttaggg
    61561 ggagtcaaga tgaaattaac taaatcaata tcatcaatgc tgtgcttatc tctagtttta
    61621 agcttatcac cagtagcata tgcaaatgaa ataagtagaa caacagttga gaatacttta
    61681 gtaggtcagg atagatatca aactgctgtt gaagtaagta aaaaaggatg gagtagtgca
    61741 aatgaggctg tagttgtaaa tagtgaatct attgtagatg cattagctgt aacaccattt
    61801 gctaaattaa aaaatgctcc tatattattg acagaaaaaa ataatctaaa ttcacaaact
    61861 gagaaagaat taaaaagatt aggagttaaa aaagtttata taattggtct atctagttct
    61921 gtatcaaatg atgtgcaaaa acagttagaa tctaataatt taactactga tagagttggt
    61981 ggtagtgata gataccaaac agctttgagt atagctaaaa aaatagaagg attaaaagat
    62041 atatcagaaa tagctgtagt aaatgggtac acaggtcttg cagatgcagt tagtatagct
    62101 tctgtagctg ctactaatgg aatggttata cttccagtat ctgatgcatc tggtatatct
    62161 agctttaaag attttataga atctaagaat ataaataaat catacataat aggctctact
    62221 aatgctgtat cagataaaat aaaacaaagt ttacctaatt cagaaagaat aggtggagca
    62281 gatagaaatg aaactaatgg taaagtaata gaaaagtttt atacatctaa taaattaaac
    62341 aatgtatttg tggctaagga tggaatgaaa aatcaaaatc aacttataga cgctttagca
    62401 gtaggagtac tagcatcaaa agaaaattct cctgtactaa tcgtaggaga acaattaagt
    62461 gcaacacaaa agagtgtatt ttcgaataaa aatgctacct ctataactca agttggtagt
    62521 ggaggaaatg aaaatgcatt taaagaatta aaagatttac aggcaaatag taacaataag
    62581 agagtaatgt atgtaactaa tacagataag gtaaatataa gaaatgatgc tacaatagaa
    62641 gcttctgtta taggatatct aaataatggt gatgaagtag aagttttaga tgtgttaaaa
    62701 actggatggg tagaaataaa atacaatgaa ggtattggat atgttagtgg gtcttatttg
    62761 acaaataata agcctgataa tagtaatgaa aatataaaaa taaagtatgt aaaagaaaaa
    62821 gatggtctaa atgttaggaa aggaccaagt acagaagatg aaaaaatagg tcacctttca
    62881 tatggaagca aagtagaaac aatagaaatg tttgctactg gatgggtaaa aataaagtat
    62941 aatggtggat atggttatgt aagtaatgat tacttatctg atacaccagt tatttaatta
    63001 taagtaacaa taaaaaaact gctttaattt gtaaagcagt ttttttataa aaatttaagt
    63061 ctaataacta tttctatttt gataccttaa tcctgggatt tattattatg gatattatca
    63121 acatacaaac actccaaatc cagtgtctaa ttccaaactt agatattaat aaattcagtc
    63181 ctgctatggt aaataagcag tatttaatta caattaaaag tgtatttata gaaagcccct
    63241 tcatagaaag tatcctaaat ccaataatag acattctaag tcctataaat gccaataata
    63301 tacctgcaat atcctgaatt aagtaatagt attcaaattt catattcaat caactcttct
    63361 ctgagcagta tcaaatattt ctaactcttc aatttcatca tctgtgtatg taagcatagt
    63421 aaaaccagtt acaccataaa taaatgaaat tataggtgta atccaactta agaaacaata
    63481 tggaataaat tctagtgggc ttacaccaag agtctgagca cagaaaacag catttgaatt
    63541 ccatggtatt aatggaccac caagtgtagc tgtatcttct ataattctag atagattttg
    63601 tggttttaat ttaaattctt tgtatattgg agacattaga gttccgacaa atacagaagt
    63661 gaacatcatt gatgaactaa atgcatttgc aaagtaactt actataaaag tagacccaac
    63721 caatttagtt cttgattttc ctattttagt tataagaggt tgaagcagta cttctaagaa
    63781 tccagttttt tggagaatac cagcaataac gaaaactaca aatactagta aaacggtttc
    63841 agccatactc attattccac cacgatttaa tagtttgtcg gcatagacaa atccagtatc
    63901 tatagtaaat cctgatagca tgtaatttaa aacatcacct attttttctc cttcttgaaa
    63961 tactgctata ataagtccca tgatagctga acttagtata gatataatgg gtggcttttg
    64021 tagcaataaa agtaataata aaaatattat tggaatcatt gctactaaac caatatgaaa
    64081 gtttgaattt aatacatcct tgatttgatt tatttgaaca tagtctatag tattatttga
    64141 atacttaaat ccaattactg tatacagaac tatacatatt acgtatgcag gtcctgtggt
    64201 ataaaacata tgcttcatat gtgtaattac atctgtctta caaactgctg cagctaagtt
    64261 tgtagaatct gatagaggtg acatcttatc tccaaagaaa gcaccagaaa tgactgcacc
    64321 agctgttaaa ccaagaggaa tacccatact agtaccaata ctcatcattg ctataccaga
    64381 agttccaaga gtcccccaag atgtaccagt agcaacagaa gttaatgaac atacgattaa
    64441 tgttgtaagc agaaaatatt taggggttat tattgttagt ccactatata ctactgttgg
    64501 tattgtacca gcagctatcc aagctgctat tagtacacca acagaaagta taattaagtt
    64561 tgattgaaag gcatctttac caacttcaaa tccaaaagct tctatttcat cattagtata
    64621 accaagtttc atagctgcag gaactactat aagccatgaa agtaaaaaca ttgtagttat
    64681 agaagcatta aatacaacta taccaactga tgttagagct attattgcaa gcattactaa
    64741 caaggaatat ctaaatgaag gtatttttct ttctgtattc attttcatag tgcaaattct
    64801 ccttaaatat ttttagttaa ttgcattttt tattcttata agagcttctt caagcatact
    64861 tcttggacaa gctaagttta ttctttgata cccacttcct ccaatgccaa agctgtttcc
    64921 ttgatttaga gcaactttac ctttttgtac aagtatactt tctagttcct catcacttaa
    64981 tccaagtgca ctaaagtcta cccataataa ataagtacct tctggttttc taactttaag
    65041 ttttggcata ttttcattta tatattttat agcaaaatct atattagatt ctaaatattc
    65101 taaaaatgat tctagccaag attcaccatt attatatgaa gcttcagttg caactaagct
    65161 aaagcaatta tttctcttta tatcaattct ggtaaaggca tcatctaaca atttatagtc
    65221 tttttcatca ggtagtatta catatgatga ttgaagacca gctatattaa aagttttagt
    65281 tggagccata caagtaattg tatttttttc aaattcttta gaaatagatg ccataggaat
    65341 atgcttatgt ttttttaata taatgtcact atgtatttca tcagatatga tttttacatt
    65401 atgcttaaga caaatatctc ctagtttttt taattcatct tttgtccata ctctaccaac
    65461 tggattatga ggattacaaa gtatgaataa ttttacatct ttaatcttgt tttcaatgtc
    65521 ttcataatcc attatgtagt ttccattttc tagtttttgt aatgggctta taattagttc
    65581 tctattgtta ttttttacaa cactattaaa agggctgtaa actggttctt gtatcattat
    65641 tttatcattt gcttttgtga gttcatttat taaaagactt atagctggga taacacctgg
    65701 actataaatt aaccactcac tttttatttt ccagttatgt ctcctatcta gccagtttac
    65761 tatagattca ttgtaagaat ctggtcttgt tgtgtagcca taaatctctt gttctagtct
    65821 attttttaag gaatcaatta tacaaggtgc agccttaaaa tccatgtcag ccacccacat
    65881 aggaagtaaa tcattagttc catacttttt ttccatttct gaccatttag atgaaaaatt
    65941 attgcttcta tcaacaatct cattaaaatt ataattcatt gtaaatacct ccagtaattt
    66001 taattttatg ttaataatat taagcaaaca acgtgccaat attgataata aaaaatattt
    66061 attcacaagt taatatttaa tattaagtaa tttcagagca tagataagat aaaaatatta
    66121 attatactta aaactttgtg gaaaaggtta tttctaataa atttttaaat atatgaaaat
    66181 gtaattaaat aggttaaata ggtttaactg tttaacttgt tagacctatt tatatttttt
    66241 agaaattcta ctccttttga tgttataatt gaacctccac gaccaacaag tatgtctaca
    66301 agcccaaagt tttgtagttc taaaagcata tttctaatct gttgttctgt caaaaatcta
    66361 ttttcctcta aagctatttt acataagctt tttctaccta ttctttcttt taaatcataa
    66421 gcctttttta aattatccaa tataaatatg tattcatcta gtgacctttt aaaattatag
    66481 tcgtatttca tgatgttttt gtctttgcca atgttgaatt gatacttttt tatattatca
    66541 cttactttat tacaaacggt tctactataa tttgaatcta tagtatctaa tatatattca
    66601 ggtaaatcac atatttctat aatatctttt tccaagtaac agaagtattc tcctaagttt
    66661 cttaattctc ttacatttcc ttcccatcta tacattttaa agatttcttt tacttcctca
    66721 cttagaataa aattacatgg aatatcatat tttaatgaac caaaaatttc aaatatatca
    66781 gcaggtcttt ccctaagtgg atgtatttta aggggaagaa cattcaacct aaaatataaa
    66841 tctcttctaa acatattttt agatacaagt tcttttaaat ttctattagt agctgcaatt
    66901 attcttacat caatgtcaat gacattatta gaaccaatac gtcgtacttg tttttcttgt
    66961 atgactctaa gtaatttaga ttgagaattt aaatccattt ctccaatttc gtctaaaaat
    67021 atagttccat tgttggctaa ttcaaataaa ccaattttcc cacctttttt agcaccagta
    67081 aaagcccctt catcatagcc aaataattca ctttgcagta gattttcttg aaaagtacta
    67141 caatttactg cgacaaaagg accatctttt ctcctagaag cactatgaat ggattgagca
    67201 aataattctt taccagtacc actttcacca attataagga tagatgaatt tgattgagcc
    67261 attttattag caattttttt tgtattaata gtttgtatac tagaacctaa tatgtcatca
    67321 aatgtgtatt tactgatatt accagagttt actagttgtg ctcttaattt agcttgcttt
    67381 ttttctaatt gagaaaactt tgtcatcttt agtataaatc catcaaatac atttaattgt
    67441 atatgtttaa tctctaaatt tatatcaata tgatttattt taatcaattt ctcaaaaaat
    67501 ggagttttat tggtcaatat gctttgaaaa ttgatgtctt ttatgcaatc accaacaaat
    67561 gagtcaatca tttcatttgc atttatagac aaaatttttc tagccatatg attatagaat
    67621 tgaattattc catcgttatt tgtgcatata attccatcat caattataga tagcaacaaa
    67681 tcaaattgtc tttcaaactt atttgcatct aacaataact cacctgtact ataacttgta
    67741 ggaattattt tttctacgta tttttttatt aggtcatctt ttattagatg ttttaatttg
    67801 gtttttgtag caatttcaac aatacaactt aaatctatta ttctgtattt taaatctata
    67861 acttcacaat ttttaaactt aggcaagatt ttttcgccag gagttaggat tacagcatct
    67921 gtgggagtaa actcaatctc tggatagcag ggcaggatat ttatattgtc tattcctaat
    67981 ctatgtatta aagaaattgt ttctattgcc atatctttac ttaagttata tacataaata
    68041 attttatctt tttctaattt ggatatcata tcaatactgt tcttttcaaa tgtcaactta
    68101 ggaacaatga tttgagcatc atagtgagat aattttacta tttcatcata ttttaaataa
    68161 gcagatagga gtataagttt ttctttaaaa aactttaaat ttccctcttc aaatgagtat
    68221 aaatttatct ttagattatc acctaagaat tgccttattt gattttcata aatttctcca
    68281 gcgtcttttt ttaaacttac aatagctaat tccatttgtt tcattttaac ctctcataca
    68341 aatttgactt attttagatt acataataat taaattagat taaataatat tatttaatta
    68401 ttattataaa tttattatag actacacatt gaagtaaaag aagtagctaa aattattcct
    68461 tttatttttg ttttttgtat ctatttggta taatagtatt agagcgtata ataatttagg
    68521 caaaattttt taaggaagac tagaggagaa tataaaatga aaaaatgtct ttactgtaat
    68581 agggatataa agtcaccaaa taataaatta gctataaaat atgatgacaa tatgaatata
    68641 tatccatgtc gtgcagaatg taaggaaaaa attgaagaat atatagcaaa aaaacctaca
    68701 tataagttta taaatatatt agaggttctt ttaggtgtgg gcggaatatt ctgctttttg
    68761 agtaaatgga ctattgcagc ccaagttgta cttggaattg atgcactggt tatattttta
    68821 ttcccattgg caggatttaa aatgaatgga aagttaagta tggaacaaac taagaatcaa
    68881 agtaggtcta ttgcaatatc aattttggca tttatagtaa taataactgt attatatttt
    68941 aaacaagttg gtaagtagag cataattgta taagacatca ttagagtatg aggtgagttt
    69001 atggaagaaa gaaaattagc accaaacaat gagagggaag ctctcataaa aagattaaaa
    69061 agaatagaag gtcaagttaa gggtatacaa aagatggtgg aacaagaacg ttattgtgtt
    69121 gatatattgg ttcaaatatc tgctataagg tctgctataa atagagtagg cacaattatc
    69181 ttagagaatc atataaaagg atgtgtagca gaaagtatta aacatgatga tgctgataaa
    69241 actgaagaga tgataaaaga gcttatggat actataaata aatttacaaa ataaggaggc
    69301 ggttagttat gaatcaacaa ggatttatta tggaaattgt tgatgataga actgcaaagt
    69361 taaaaatgca aagacattca gcttgtgctg cttgtggaaa atgtgctact acaaattcag
    69421 cagagtcaaa agaaatatta gtagaagtag acaacacaat tggtgcaaaa gttggtgacc
    69481 atgtagaagt gagtatggat aatatgaatg tattaaaagc agctgtaatg gcttatataa
    69541 tacctcttat agcacttctt gtaggaacaa tagggactta ttatatattg ggggcaattg
    69601 gaatgacaac tggagttgaa gccataagtg gattagttgg aatttgtctt acaataatct
    69661 gttatttata cttaaagaag aatgacaaaa aatttagaga cagtagagaa tttataccag
    69721 taataacaag aatattaatt gacctttaag ataattataa ttaaaaaata gcaatgtact
    69781 ttttaaataa atactcaata cgtatttgta gagtttaagt acattgctat ttttatattt
    69841 ttattttgat tttctgtaag gaataaagtt ttttctgatt tttaaaagat tcaatgttct
    69901 tacaaaagaa gttacaacta atacaccaag tgctattgca gcacttagaa atagcgcatc
    69961 tgtacctttt gacatagcca aagaataatt tttctgaatc aaagacaaca ttgtattata
    70021 tagcccaatt cctggtatta gaggaagaat acctggaatt acgaacacaa tagctggttg
    70081 ctttagtttt cttgctaaag tctcactgca cgctgagacc aaagcagcag cgataaaacc
    70141 tgcaaaaact gcatttgtag taaaattaaa taaataaaca tatacaatcc aaccaattcc
    70201 gccagttact ccagctggaa gaagtagata tagtggagca ttaaagaaaa cagcaaatcc
    70261 agcagttgca acacctgaaa ataaaaaatg caaaatcata gacatatcag tcattagaaa
    70321 ggacctccta ttctatacca tgtatcaagg acaaaaccaa ctccagaagc aattgcaata
    70381 ataatcatag cagcatcaaa agcacgagaa attcctgata ttaaattccc tgatattaaa
    70441 tctctaatag cttttataaa agcaactcct gggagtagtg gcattatagc gccgactata
    70501 agcattttag ggtcatctaa aatgcctatt tcaactagta gaactcctga aagtgcaatt
    70561 aaaaaagaag atactaaaca ggaaaatgca gatattgcac ttatcttcat cgttttatca
    70621 taagtaattg cagcaaagat tgctattata aacgtaagta taaaatttaa tacataattc
    70681 cctccaagca aacaagcaaa acaagcagat gcaattcctg tacaagagta aaataaccat
    70741 aaaggataag gttttacatc ttggatttca taaagacgtg caatggcatt atcaatatca
    70801 tactctttgt cactaacaaa ttctcgagaa aaactgttta ataaagaaat cttatttaag
    70861 tttatacctc ttgattgaat cgttttcata aacgaaaagc catcaaattt ctcatctgaa
    70921 ataattatta ctgtaggagt tgtaaaaata tttacatgat aaaaccctct tgacctgcat
    70981 attctaagga cactgtcttc aaccctagat gtttcagctc cattttttat catcagttcc
    71041 cctacaaata gagctagttt tagaatattt ttcttatatt caagttcctc attttgattc
    71101 ataaatacac ctccaaatta aaaaacgtaa tattgaaatt atatcaaatt tttaagtaat
    71161 attccttaat atctatacaa atatattatc ttttttttgt ttcaaaatag tcacatttaa
    71221 attatatcca attaaaagaa ttagacaata ttatttatta tattttaact taaaaataaa
    71281 gaaagtaact atgttaaata tggaaaaatg gcaaaacact tgactattaa ttggtaaagg
    71341 actataataa taaattatca tattgataaa aacgaaaatt atgaaatgtc tgtaaaaata
    71401 aaatttaaat aataactagg aggagtaata tgtttgagaa cttgaaaaaa gcggaccctg
    71461 agatttatga aagtatgaaa agagagttaa aaagacaaca aagaaatatt gaattaatag
    71521 catcagaaaa catagtatca gttccagtaa tggaaactat gggaagtcat cttacaaata
    71581 agtatgcaga aggttactca ggcaaaagat attatggtgg atgtgaatac atagatgaag
    71641 ttgaaactct tgcaatagat agaatcaaaa aaatatttgg agcagaacat gctaatgttc
    71701 aacctcactc tggagcaaat gcaaatattg gtgtatattt tgctatgtta aaaccaggtg
    71761 atgttgttat gggaatgaat ttatctcaag gtggacattt aactcatggt gctccagtta
    71821 atatttctgg tcaatattat aaattttatg aatatggtat agataaagac agtggactta
    71881 tagattttga tgaagttaga aagatagcac atgaagtaaa acctaaaatg atagttgcag
    71941 gagcaagtgc atatcctaga gaaatagatt ttaaaaagtt tagagagata gctgatgagg
    72001 ttggagcatt gcttatggta gatatggctc atatagcagg tcttgtggct gctggtcttc
    72061 accaaaatcc atgtgaagtg gctgattttg ttacaacaac aactcacaaa actttaagag
    72121 gacctcgagg gggtgttatt ctttgtaaag aaaaatatgc taaagacata gacaaagcaa
    72181 tattccctgg tattcaaggt ggacctcttg aacatataat tgcttctaag gcagtttgct
    72241 ttaaagaagc tttaagtgat gagtttaaag aatatcaggt acaagttgct aaaaatgcaa
    72301 aagccttagc tgaagaactt attaaaagag attttaaatt gatttctgga ggtacagata
    72361 atcatttaat actattagat ttgactaata aaaatataac tggtaaagca gcagaaaaga
    72421 gattggatga tgcttatata acagctaata aaaatacaat tccatttgac ccaaatggtg
    72481 ctcttattac aagtggaata agacttggta ctccagctgt aactactaga ggtatgaaag
    72541 aagaagatat ggcaataatc gctgaggcta tagacctatg tttaacttat gatgaagaat
    72601 ctaaggctag aacattggtt gttggtttaa ctgaaaaata tcctttatat gaagaatata
    72661 atattatgga ttaattataa agaacaacta aataaaatac atttaaataa ttacaatgat
    72721 tgtgtatgta tttgaatata gttagatata aaaaaggtgt ctcaaaatga actttttagt
    72781 ttatgaggca cttttttgta tggaatcgaa catatttgtg ttatttaaat aataaaaaat
    72841 atggttatct ctatttttag atggtctctt tgtatttttt aattaaaact ttaagatttc
    72901 ttaagaatta tactaggttt ttctaaagat ttaaagtcta tacttataag tatagtaatc
    72961 atatgaaaag aaaagcttta acgaggaggg aatcttatga aggtattaat tcttacagga
    73021 aaatttggta tgggtcatta ctcagcatca aattctttaa gtgaagatat aaaagcaaaa
    73081 tttgataatt cagaaataat aattaaagat atatttgagt acattatgcc taactattca
    73141 gataaaatgt acaagacttt ttctattctt gtaaatcggg gaagtagtct ttataattta
    73201 ttttataaat gtgctgaaaa tggaaagaaa gatataaaat ttactttttc agattatttt
    73261 ttaaataaat tagatacatt acttcatgaa gtacaaccaa cagtagttat ttcaactttt
    73321 ccattttgtt ctcaattagt atcaagatat aaggaaaaat ataactcaaa tcttccttta
    73381 ataacatgta taactgatat aagtagtcac tcagaatgga ttagtaaaaa tacagactgt
    73441 tatttagtag ctagtaaatc tactaaggaa gaacttgttt ttaaaggaat agatgaatct
    73501 aagattaaag ttaatggtat tccagtaaaa aaagaattta aaagaataga acatgtaaat
    73561 cattcaacta aaaaaaatat tcttataatg ggtggaggat taggattact gcctaaatca
    73621 gaacaatttt acaaagaatt aaatagttta gaaggagtaa aaactactgt aataactggt
    73681 aataataaaa aaatgtacta taaactatat ggtagatatg aaaatataga ggtagtaggt
    73741 tacaccaatg aagtatataa atatatgaaa gattctgacc ttattatttc taaaccaggt
    73801 ggaataacac tatttgaaac aatttattca gaacttccaa tattggcatt taatccattt
    73861 ttacaacaag agatagataa tgctagtttt atattaaata atgaaattgg gagaatactt
    73921 ggtaaaaata aaaaatacta tgtagatgag ataaaagatt taatttatga tgatgctact
    73981 cttaaagaaa tgagcagtaa catgaaagaa ttaaaaaaac aatttgataa taatacctta
    74041 gagaatattt tattttcact tgatgaacaa ggagcgtgta gagaatgtat gtagtaggtt
    74101 taattatcgt tgttgcattg atttttttag tccattcaat tatacctaca tactataata
    74161 aactattaaa taaagaggta ttaaaaaata tggctggaga aaatgaaatt gcacttacat
    74221 ttgatgatgg tccagataag agatatacag aaaaattact agatgtgtta aaagaaaatg
    74281 atatacaagc tatgtttttt gtagtagcaa agaatgctga aaaagagcct gaaattataa
    74341 aaagaatgtt gagagaaaat catatagttg gtttacattc attggaacac agaaatgcat
    74401 ggctttatag ttatagttat gttaaaaaag attttattga aagtacaaat ataatgaaaa
    74461 atttaggtgt agatgtaaac tactatcgtc caccatgggg tcatactaat atattttcaa
    74521 attcatttgt taaaaaatat aatctaaaaa tgactttgtg ggatgtaatg gcagaagatt
    74581 gggagaaaga tagtacagta gacattatta taaacaagtt aatgagtaga acaaaagaaa
    74641 attctataat ttgtttacat gatgcaggtg aaaattcagg tggtgcagta ggtgcacctg
    74701 agcgtactat tgaagcttta aagatagcta ttccaaaact taaagccagt ggtttaaagt
    74761 tcgtaacacc agaaaggatg tagttatgat aagtaaaact gaaaagaaaa ataaatgcct
    74821 aggtagtgta gcttttttag ttttactaat gggcataaca ggatattttg tttttagagg
    74881 gcagtcagtt gaatcattga taaaatcatt aaaaggtgca agccctatgt ttatactaat
    74941 tggatttgca atgatgttta tatatgttgc ctgtgaaggt ataaatatat acttaggtat
    75001 gaaagcttta aaccaaaaga ctactctttt aaaatgtatg ggatatgctt ttattggatt
    75061 ttattttagt tctattacac cttcagcatc aggtggtcaa ccagcacaag tttattatat
    75121 gaaaaaagac gatataaata tatcatattc ttcacttata ctattagtca ttgttgttat
    75181 tcaccaagta gttatactgg catatagtgg aataatgttc attatggaac gtgagtttat
    75241 attaaataat gtaagtggta tgaacatttt actaatatat ggtgtaataa caaatgttgc
    75301 tcttgtcatt ggagtaattg caattatatt ttcaaaaaaa cttgtaaaca attttataat
    75361 atcaataaca aatttattag gtaagttaag aataataaaa gatgttgaaa gttcaagaaa
    75421 agttataata tctcaaattg aagagtatgt taaaggtgct caatatataa agcagaatcc
    75481 aaaacttgta gtccaaattt tagtcataac tattgtacaa ataacagcta tgtttttagt
    75541 tcctttcttt gtatacaaag cttttcatct atcaacatat actgtatttg agatattagc
    75601 gatacaatcc ttgcttaata ttgctgtttc ttcattacca ttgccagggg ctgttggagc
    75661 ttctgaaaat agttttatga cattatttaa gatatttttc cctggtcact tattagttcc
    75721 ggcaatgtta cttagtaggg gaataagttt ttatgcattt gtagctataa gtggattgat
    75781 atgtatagta gtacatgtaa aatcttctga aaaagtaaaa gcagtgaaaa aagttgctta
    75841 tgtaagataa tattatatag attattttta ttaatatgtc aatttgtgtg tatattttaa
    75901 ttaagcttta aacatattta caggagtaga aactattaaa acgtgtgaca ttgctaagct
    75961 tttgctaata aagtataata ttttatatag tttgaaatat ttaagaaata tagcaaaaaa
    76021 aggagcttgg tgatgaataa agagattcca aaaaaaattt tagtagctga tgataatcct
    76081 gagattaggg aaatcgtaga aatactttta actggtgaag gttatgaagt tattatggca
    76141 acgaatggag aagaagctgt aaacttagta gatagtacga ttgatttgat tattttggat
    76201 gttgtaatgc ctgtaaaaac aggatttgtt gcatgtaatg aaattagaga aaaaacgaca
    76261 gcaccaatat tatttttaac tgcaaaaact caagactctg ataaagttat tggattttca
    76321 gcaggaggag atgactattt atcaaagcct ttttcatatt ctgaactaat ttcaagagtt
    76381 aagtctctac ttagacgtta ttatatatac cagggaaagg aaaaggaaag agagccaaat
    76441 atattaaaaa caaaagagtt atgtgtcaat ttagatactc aagatgttac actaaatgga
    76501 gaacctgtgt ttttgacaac tatagaatat agtatattaa ttcttatgtt gaaaaataga
    76561 aaaaaagttt tttcgtctga aaatttatat gaaactattt gggatgagca gtatttttat
    76621 acagcaaata atacaataat ggttcatatt agaaatttaa gaaaaaagtt agaaaaagac
    76681 caaaaaaatc cacaatatat aaaaaccgca tggggaaagg ggtattatat tgattaacaa
    76741 aattaagcca tctaagttgg gagttatact attgatatat gtagtaatct cagctgcagt
    76801 ggctttcatt ttaaatatac cattttactc tgctgttgaa tctatagtaa aagatgtatc
    76861 agaagggaaa gtatatttta aaagagaagt aaatcaactt atggataatt ttcaaactta
    76921 tgtgaataac aatggtataa gagcagatga tggagatgat atagcaaaat ggaatagtga
    76981 taattggttt gtttctatga agatatataa aggaaataag gttttttatg atacattata
    77041 ctatcctaat gaagtacctg ataagagtga ggaaaatgag ttttatagca gtcccatggc
    77101 tagaaactat gagatacaat tttctgatat taaagctaat atagttgtag tagctttatt
    77161 tagatttaga tttcaaaatt ttatagaagc aatttctatt acatttatgg cacttacatt
    77221 tattataaca tttttactgt tgtttagtag aaagataaag tacctaagga aaatagaaat
    77281 gggtataaag atagtagaga gtggcagttt aaagtataga ataccagtaa aaggtaatga
    77341 tgaattatca tcacttgcat ctagtattaa tgagatgagt catacattgg agaatcaact
    77401 tataaaagaa agggagatga agaataaaaa taaagatata gtaacttcaa tatcacatga
    77461 tgttagaact ccattaacgt cagtaatttg ttatttagat ttgattaaag accataaata
    77521 caatagtcct gagcaattgg aacaatacat aaaaaatgta aggtctaaag catatcaaat
    77581 aaaagattta acagatgacc tttttacgca ttttgttaat tctggagagg aagtttcaaa
    77641 agggtatgaa aaaataaatg ctaatgaatt tatttttcaa ttacttttag atagttcata
    77701 tacattggag gagaaaggat ttcatataac aatagaaaat gaactttata accaatatca
    77761 tatttatgta gatgttacac aatttagaag gatatttgat aatttatgtt ctaatataat
    77821 aaaatatgct aggaaagata agcctatagt atttttaatt aaagtagagg attctaaatt
    77881 actaattata caaaaaaata gagtaagtaa tttttctaag aatgtagaaa gttttggaat
    77941 tggtataaag aattgtgaga aaatagttgc atatcataat ggaagcataa atgtaaattc
    78001 agatgataaa gaatttgcta ttgaaatatc tattccagca aaagaatcat aaaaatttaa
    78061 attatatatt gtgtaattgc tattatatat tgtgtaattg cttatgtaaa attctatgaa
    78121 gcaggaagca tgtgacttta gttatgggat gttcaatatt gtgtacctct aggcaagtaa
    78181 caagtttact tacaagacca tataatatta ttatcttaaa aaaaggggac ataataatat
    78241 ggttttgaca ggagcacatt atatttacat tctatttatg gtaattatat taattactat
    78301 gattatgaaa aaggatacaa tagtaccatg tatattaggt gtttttttta tggggttgtt
    78361 ctttgaaaaa aacatttttg gtgctataac agcagtgttt aactctttta ttatatcttt
    78421 aaatgagttg ggtccaatta tcttgattat agctattatg gttgcattat ctaaagccct
    78481 agaagccaat aatgctatac agtatatggt gagaccattt tcgagagtta taaaaaattc
    78541 taatacagca ttttttgtaa ctggatttgt tatgttagtt ctttcttggt ttttctggcc
    78601 aactccagct gttgccttag ttggagctgt atttttacct gttgctatga gagctgggct
    78661 accagcaatt ggtgttgcag tagcattaaa tttatttggt catggtcttg ccttgtctac
    78721 agactttgtt attcaaggag ctccaagtat aacagctggt gcagcaggtg ttgcagtatc
    78781 atatgttata aatgatggta tgattttgtt ttgggtgatg ggaatcgtaa ccatatctat
    78841 ggcattttat acattaaaaa gagatattaa caaaggaatg tttagagaag aactaaaagg
    78901 ttttgaaagt gaagaagtag aagagttcaa tggaaaatct aaaatagcaa ctattttagt
    78961 agctctggga tttcttgctg atataattgc tatgtatata tttgacctaa aaggaggaga
    79021 tgcatcagct cttttgggtg gaacagcagt atttttaata ataattataa atgttataaa
    79081 ttttggcaaa gatagtcttg aaaatgtatg tgagaatata attgatggtt ttgtgtttgg
    79141 gataaaaata tttggagcaa ttataccaat agcagcattt ttctatatgg gtgaagttgc
    79201 accattgaca ggtgtatttg gaaaagtatt agcaccaggt tcacaaggtt tattatcaga
    79261 tataggcata gctctttctc aaacaatacc acttaataaa tttgccgtat caggtataga
    79321 aactgtagtg ggagcaataa ctgggcttga tggttctgga ttttctggga tttcattagt
    79381 tggttcactt gcctctgtat ttggaactgc tataaatgca agtgttggtg cactagctgc
    79441 attaggacaa atcagtggta tatgggtagg tggaggctgt ctagttcctt ggggtcttat
    79501 ttcagcagcg gcaatttgtg gagttagtcc aatagaattg gcaaagcgaa actttgtccc
    79561 agttataacc ggattggttg taacaaccat agtagcaatg tttattattt aataaatcga
    79621 ataaatcttt aattgtataa attaaaaata gatgtgtagc tataatttat tataattgtt
    79681 ttactaattc taagccatac atctattttt attgatattt ttattagtat tctttaataa
    79741 aataatattt ttcattatac tatacataac atctaaatat aacatctaaa atactgttat
    79801 ctatatttaa tatcttgcca aattttttga tgttttattg ccctgtccca ccaacatata
    79861 taagctatca caagttttta cctatactat caccaaacaa aaattctaat tttaatttat
    79921 tattttataa cctatattat attaactata ttagtttgta gactttagat gtaattataa
    79981 atattaatac tccaagagtt caaattcata tcctagtttt cttgcatttg atataaaatc
    80041 atttaaaatt tctgtactag ttttggaaac tgcatgtagt aacaagatag aaccatcatg
    80101 tagattatcc attatttttt gcgttgcttc ttcatgtgat ggttgtttat cagtatccca
    80161 gtctctgtat gcaaaactcc aaaatacagt cttgtatcct aaatttttag tcattgccaa
    80221 gcttttttct gagtattttc ccataggagg tctaaaaaat ttaaccatat ctttcccagt
    80281 tacatcttta tataactttt caacatcata taattcgtca ttaaagtttt ttagattgct
    80341 tgtttttgtt ggcatagatg gatgggtttt actatgattt ccaactatat gtccctcaga
    80401 aaccattctt tttactaaat ctttattttc ttttatatat ggagctgtaa caaaaaaaac
    80461 tgctttaacc tgattttgtt ttagagtgtc gagtattttt gtagtgtatc cattttcata
    80521 accttcatca aatgtaagat atagtgtttt ttgaccatct tttgtaggtc cattgtatag
    80581 ggcatcatag tcagaaaatt taaattcaat gtccgtattt acttctggtg ttttatgctt
    80641 attgtttggt atataaaacc aatcaagagt agtgttatct aaagaagata catctaattt
    80701 attattatca ttattagtag tggcttttga tggtttatct gttccgtctg aaactattac
    80761 attggaagta tctttaccac tatctatttt ttccttatct tcttgtaact gtgtttcctt
    80821 attttgattt tcgttttgat tgttttgtga atttgaacat ccaacaataa aaaaaataga
    80881 aatagaaagt agtgttaaat aatgcaatac ttttctaaac attttgaagc tcctttctaa
    80941 attaataata attgcatata ataataatta tatgattaat tacaattgca tatagtatta
    81001 ttataattgg aaattactat taataatagt tatatcttta aaaataaggt cacaatagta
    81061 tgacaaaggg tgaataatca ataaatttaa aaaaaaatga aaaaaatagt tgaccatatt
    81121 atgagaagat gttattataa taaatgtgct caacaagaag taacaaaata acaagcacaa
    81181 agaagttaat tgaat
//
LOCUS       DAYAKB010000009        81038 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.009, whole genome shotgun sequence.
ACCESSION   DAYAKB010000009 DAYAKB010000000
VERSION     DAYAKB010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81038
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.009"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..185
                     /locus_tag="ACGI3L_000740"
     CDS             <1..185
                     /locus_tag="ACGI3L_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase"
                     /protein_id="HFG9196467.1"
                     /translation="KECFNLKDLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPEL
                     NEKEILKEKALNIYTF"
     gene            418..1731
                     /locus_tag="ACGI3L_000741"
     CDS             418..1731
                     /locus_tag="ACGI3L_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9196468.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            1903..3078
                     /gene="hemW"
                     /locus_tag="ACGI3L_000742"
     CDS             1903..3078
                     /gene="hemW"
                     /locus_tag="ACGI3L_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFG9196469.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            3181..4200
                     /gene="hrcA"
                     /locus_tag="ACGI3L_000743"
     CDS             3181..4200
                     /gene="hrcA"
                     /locus_tag="ACGI3L_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFG9196470.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            4230..4850
                     /gene="grpE"
                     /locus_tag="ACGI3L_000744"
     CDS             4230..4850
                     /gene="grpE"
                     /locus_tag="ACGI3L_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFG9196471.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            4942..6789
                     /gene="dnaK"
                     /locus_tag="ACGI3L_000745"
     CDS             4942..6789
                     /gene="dnaK"
                     /locus_tag="ACGI3L_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFG9196472.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            7000..8154
                     /gene="dnaJ"
                     /locus_tag="ACGI3L_000746"
     CDS             7000..8154
                     /gene="dnaJ"
                     /locus_tag="ACGI3L_000746"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFG9196473.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            9120..10055
                     /locus_tag="ACGI3L_000747"
     CDS             9120..10055
                     /locus_tag="ACGI3L_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9196474.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            10091..11464
                     /locus_tag="ACGI3L_000748"
     CDS             10091..11464
                     /locus_tag="ACGI3L_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9196475.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(11652..12419)
                     /locus_tag="ACGI3L_000749"
     CDS             complement(11652..12419)
                     /locus_tag="ACGI3L_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HFG9196476.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDFI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(12449..13558)
                     /locus_tag="ACGI3L_000750"
     CDS             complement(12449..13558)
                     /locus_tag="ACGI3L_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196477.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRNLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            13816..14553
                     /gene="cas6"
                     /locus_tag="ACGI3L_000751"
     CDS             13816..14553
                     /gene="cas6"
                     /locus_tag="ACGI3L_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HFG9196478.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPINFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            14558..16033
                     /locus_tag="ACGI3L_000752"
     CDS             14558..16033
                     /locus_tag="ACGI3L_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196479.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENRLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYSFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKRMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            16053..17066
                     /locus_tag="ACGI3L_000753"
     CDS             16053..17066
                     /locus_tag="ACGI3L_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HFG9196480.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            17082..17879
                     /gene="cas5"
                     /locus_tag="ACGI3L_000754"
     CDS             17082..17879
                     /gene="cas5"
                     /locus_tag="ACGI3L_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HFG9196481.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYIKMGKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVKLKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            17906..20314
                     /locus_tag="ACGI3L_000755"
     CDS             17906..20314
                     /locus_tag="ACGI3L_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HFG9196482.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            20755..21702
                     /gene="prmA"
                     /locus_tag="ACGI3L_000756"
     CDS             20755..21702
                     /gene="prmA"
                     /locus_tag="ACGI3L_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFG9196483.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            21721..22479
                     /locus_tag="ACGI3L_000757"
     CDS             21721..22479
                     /locus_tag="ACGI3L_000757"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFG9196484.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEIILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNSVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            22481..23779
                     /gene="mtaB"
                     /locus_tag="ACGI3L_000758"
     CDS             22481..23779
                     /gene="mtaB"
                     /locus_tag="ACGI3L_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0061712 - tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HFG9196485.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            23822..24172
                     /locus_tag="ACGI3L_000759"
     CDS             23822..24172
                     /locus_tag="ACGI3L_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HFG9196486.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            24335..24514
                     /gene="rpsU"
                     /locus_tag="ACGI3L_000760"
     CDS             24335..24514
                     /gene="rpsU"
                     /locus_tag="ACGI3L_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFG9196487.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            24544..24987
                     /locus_tag="ACGI3L_000761"
     CDS             24544..24987
                     /locus_tag="ACGI3L_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFG9196488.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            25098..25595
                     /locus_tag="ACGI3L_000762"
     CDS             25098..25595
                     /locus_tag="ACGI3L_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFG9196489.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            25788..26351
                     /gene="raiA"
                     /locus_tag="ACGI3L_000763"
     CDS             25788..26351
                     /gene="raiA"
                     /locus_tag="ACGI3L_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFG9196490.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            26564..26800
                     /locus_tag="ACGI3L_000764"
     CDS             26564..26800
                     /locus_tag="ACGI3L_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HFG9196491.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            26813..28156
                     /gene="yqfD"
                     /locus_tag="ACGI3L_000765"
     CDS             26813..28156
                     /gene="yqfD"
                     /locus_tag="ACGI3L_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HFG9196492.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            28095..29210
                     /locus_tag="ACGI3L_000766"
     CDS             28095..29210
                     /locus_tag="ACGI3L_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFG9196493.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            29267..29728
                     /gene="ybeY"
                     /locus_tag="ACGI3L_000767"
     CDS             29267..29728
                     /gene="ybeY"
                     /locus_tag="ACGI3L_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFG9196494.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            29734..30453
                     /locus_tag="ACGI3L_000768"
     CDS             29734..30453
                     /locus_tag="ACGI3L_000768"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFG9196495.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            30572..30973
                     /locus_tag="ACGI3L_000769"
     CDS             30572..30973
                     /locus_tag="ACGI3L_000769"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFG9196496.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            31037..31930
                     /gene="era"
                     /locus_tag="ACGI3L_000770"
     CDS             31037..31930
                     /gene="era"
                     /locus_tag="ACGI3L_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFG9196497.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            31942..33321
                     /gene="mgtE"
                     /locus_tag="ACGI3L_000771"
     CDS             31942..33321
                     /gene="mgtE"
                     /locus_tag="ACGI3L_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFG9196498.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            33394..33549
                     /locus_tag="ACGI3L_000772"
     CDS             33394..33549
                     /locus_tag="ACGI3L_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HFG9196499.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            33515..34288
                     /gene="recO"
                     /locus_tag="ACGI3L_000773"
     CDS             33515..34288
                     /gene="recO"
                     /locus_tag="ACGI3L_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFG9196500.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            34281..34880
                     /locus_tag="ACGI3L_000774"
     CDS             34281..34880
                     /locus_tag="ACGI3L_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HFG9196501.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            35040..35918
                     /gene="glyQ"
                     /locus_tag="ACGI3L_000775"
     CDS             35040..35918
                     /gene="glyQ"
                     /locus_tag="ACGI3L_000775"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFG9196502.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            35918..37984
                     /gene="glyS"
                     /locus_tag="ACGI3L_000776"
     CDS             35918..37984
                     /gene="glyS"
                     /locus_tag="ACGI3L_000776"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFG9196503.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(38150..39697)
                     /locus_tag="ACGI3L_000777"
     CDS             complement(38150..39697)
                     /locus_tag="ACGI3L_000777"
                     /EC_number="1.8.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HFG9196504.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEKLFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNKEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            39977..40744
                     /locus_tag="ACGI3L_000778"
     CDS             39977..40744
                     /locus_tag="ACGI3L_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFG9196505.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            41027..41224
                     /locus_tag="ACGI3L_000779"
     CDS             41027..41224
                     /locus_tag="ACGI3L_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9196506.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            41253..42329
                     /gene="vorB"
                     /locus_tag="ACGI3L_000780"
     CDS             41253..42329
                     /gene="vorB"
                     /locus_tag="ACGI3L_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HFG9196507.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            42332..43051
                     /locus_tag="ACGI3L_000781"
     CDS             42332..43051
                     /locus_tag="ACGI3L_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HFG9196508.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            43064..43603
                     /locus_tag="ACGI3L_000782"
     CDS             43064..43603
                     /locus_tag="ACGI3L_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HFG9196509.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            43760..44818
                     /gene="buk"
                     /locus_tag="ACGI3L_000783"
     CDS             43760..44818
                     /gene="buk"
                     /locus_tag="ACGI3L_000783"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HFG9196510.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            44836..45729
                     /locus_tag="ACGI3L_000784"
     CDS             44836..45729
                     /locus_tag="ACGI3L_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HFG9196511.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            45759..46967
                     /locus_tag="ACGI3L_000785"
     CDS             45759..46967
                     /locus_tag="ACGI3L_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9196512.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            46991..48250
                     /locus_tag="ACGI3L_000786"
     CDS             46991..48250
                     /locus_tag="ACGI3L_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9196513.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            48895..50358
                     /locus_tag="ACGI3L_000787"
     CDS             48895..50358
                     /locus_tag="ACGI3L_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFG9196514.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            50414..51550
                     /locus_tag="ACGI3L_000788"
     CDS             50414..51550
                     /locus_tag="ACGI3L_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9196515.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            51786..52901
                     /locus_tag="ACGI3L_000789"
     CDS             51786..52901
                     /locus_tag="ACGI3L_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C45 family autoproteolytic
                     acyltransferase/hydrolase"
                     /protein_id="HFG9196516.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            53053..53922
                     /locus_tag="ACGI3L_000790"
     CDS             53053..53922
                     /locus_tag="ACGI3L_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HFG9196517.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSRRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            54298..54843
                     /locus_tag="ACGI3L_000791"
     CDS             54298..54843
                     /locus_tag="ACGI3L_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFG9196518.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            54856..55869
                     /locus_tag="ACGI3L_000792"
     CDS             54856..55869
                     /locus_tag="ACGI3L_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFG9196519.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            56091..58064
                     /locus_tag="ACGI3L_000793"
     CDS             56091..58064
                     /locus_tag="ACGI3L_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9196520.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSINEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            58133..58492
                     /locus_tag="ACGI3L_000794"
     CDS             58133..58492
                     /locus_tag="ACGI3L_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFG9196521.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            58527..58883
                     /locus_tag="ACGI3L_000795"
     CDS             58527..58883
                     /locus_tag="ACGI3L_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFG9196522.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            58920..60212
                     /locus_tag="ACGI3L_000796"
     CDS             58920..60212
                     /locus_tag="ACGI3L_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFG9196523.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDIDLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            60648..61286
                     /locus_tag="ACGI3L_000797"
     CDS             60648..61286
                     /locus_tag="ACGI3L_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196524.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            61293..62135
                     /locus_tag="ACGI3L_000798"
     CDS             61293..62135
                     /locus_tag="ACGI3L_000798"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFG9196525.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            62196..64823
                     /gene="ppdK"
                     /locus_tag="ACGI3L_000799"
     CDS             62196..64823
                     /gene="ppdK"
                     /locus_tag="ACGI3L_000799"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HFG9196526.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            65037..65282
                     /locus_tag="ACGI3L_000800"
     CDS             65037..65282
                     /locus_tag="ACGI3L_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9196527.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(65571..66881)
                     /locus_tag="ACGI3L_000801"
     CDS             complement(65571..66881)
                     /locus_tag="ACGI3L_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HFG9196528.1"
                     /translation="MNKKMSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSD
                     SNKRTSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFP
                     YDQIGLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMK
                     LKKDLGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEY
                     RFESFRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVA
                     PTKPEQGNLTDDEYKVLTDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFN
                     TENGLVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGL
                     ITLTDYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(66903..70037)
                     /locus_tag="ACGI3L_000802"
     CDS             complement(66903..70037)
                     /locus_tag="ACGI3L_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HFG9196529.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            complement(70041..71264)
                     /locus_tag="ACGI3L_000803"
     CDS             complement(70041..71264)
                     /locus_tag="ACGI3L_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFG9196530.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPSILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            71516..72001
                     /locus_tag="ACGI3L_000804"
     CDS             71516..72001
                     /locus_tag="ACGI3L_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9196531.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            complement(72112..74340)
                     /locus_tag="ACGI3L_000805"
     CDS             complement(72112..74340)
                     /locus_tag="ACGI3L_000805"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFG9196532.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            74453..74884
                     /gene="dut"
                     /locus_tag="ACGI3L_000806"
     CDS             74453..74884
                     /gene="dut"
                     /locus_tag="ACGI3L_000806"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFG9196533.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            75144..76334
                     /locus_tag="ACGI3L_000807"
     CDS             75144..76334
                     /locus_tag="ACGI3L_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9196534.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(76569..77141)
                     /locus_tag="ACGI3L_000808"
     CDS             complement(76569..77141)
                     /locus_tag="ACGI3L_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9196535.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(77170..77436)
                     /locus_tag="ACGI3L_000809"
     CDS             complement(77170..77436)
                     /locus_tag="ACGI3L_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HFG9196536.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(77436..77645)
                     /locus_tag="ACGI3L_000810"
     CDS             complement(77436..77645)
                     /locus_tag="ACGI3L_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HFG9196537.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            77914..78774
                     /locus_tag="ACGI3L_000811"
     CDS             77914..78774
                     /locus_tag="ACGI3L_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFG9196538.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            78822..79850
                     /locus_tag="ACGI3L_000812"
     CDS             78822..79850
                     /locus_tag="ACGI3L_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFG9196539.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVVYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            80221..80727
                     /locus_tag="ACGI3L_000813"
     CDS             80221..80727
                     /locus_tag="ACGI3L_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HFG9196540.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT        31389 a         9011 c        14300 g        26338 t
ORIGIN      
        1 aaaaggagtg ctttaatctt aaagatttag ctattaatgg aaaagatttg atatctatag
       61 gtataaaacc aggtaaagat ataggatata ttttaaataa gatgcttgaa atagtcataa
      121 ataatccaga gttaaatgaa aaagaaatac taaaagaaaa agcattaaat atatatacat
      181 tttagattca aatataaaaa atttaattac tttaaaaaac atagaataaa atacttattt
      241 agataaaata aataattttt agagaatatt ttagaagtta cgattgtatg atttttaaat
      301 gcataggcat ttactctagg actatagact aatataaaaa aaaactttgg gaatactaaa
      361 accataaatt tataaaatta atattttata tactgtaaaa cagtgaggag ggacagtatg
      421 catactcaac tacaaaagac tattggtctt tcagcagctc tttctactgt tgtaggtatg
      481 gttataggtt cgggagtttt ttttaagcca caagcaatat acactacaac taatggagct
      541 ccaggtctag gtattatagc gtggctttta ggtggtttta taacaataac tgctgggctt
      601 acagctacag aaatttcagc tgctatacca aaaactggtg gtatgatgat ttatatcgaa
      661 gaaatatatg gagaaaagtt aggtttttta actggatgga tgcaaactgt attatttttc
      721 ccaggtacat cagcggcatt aggagtaata tttgctcaac aagcatctga acttttagga
      781 atgagcccaa ataatatggc aaatgtactt cctatagcaa ttggagttat actattttta
      841 gcgttattaa atataatagg ttcatcctta ggaggaaaag ttcagacagt agccactatt
      901 ggaaagatga tacctttaat tttaataata gtctttggat ttattaaagg tcaaagtagt
      961 gaagtattaa atccatttgt aggagatggt gtaaatgcat caaatgcact tggacaagta
     1021 ttaatagcta ctttgtttgc atatgatggt tggataaatg ttggagctat atcaggagaa
     1081 atgaagtctc cagagaaaga tttaccaaga gcaatagttg gtggtttatc attagttatg
     1141 gcagtttata ttataataaa tatagcttat ctttgggtag taccagcaag tgaattagca
     1201 acagttactt ccccagctac attagtagca acaagattgt ttggaaatat aggtggaaaa
     1261 gtaataactg tgggtatatt aatatcagta tttgggacat tgaatggata tttattaaca
     1321 ggttcaagga taccttatac attagctgaa atgggaactt taccagcatc taaaactctt
     1381 ttaaaagtaa attctggagg ttctcctgta aattcaatac tacttataac tgtgttagcc
     1441 tgtgtatatg cattatctgg tcaatttaat cttttgacag acttaacaat attttcaata
     1501 tgggtatttt atgtattgac ttttataggt gttatgaggc ttagaagaca aaagccagat
     1561 ttacacagac catataaagt ccctttatat ccaataatac caattatagc tatattaggt
     1621 ggactgtttg taataataaa tcaaatattg acttcaacag tcatatcttt aggcggaata
     1681 tttataacac tattaggttt accagtttat tattatatga aaaaaagata actacttaat
     1741 ttaagttaga taaatttggg taaaggtgaa aattaacttt tatccaaatt ttttatactg
     1801 ttatacaata taagtattat atattgcttg atgtgctatt ttgtttgatt tataatttag
     1861 taattgatgt tttaagataa tttaagaaat gaggagtgaa agatgctagg actttatgta
     1921 catattccat tttgtgtgaa aaaatgtaag tattgtgatt ttaattctta taaaatggac
     1981 atagattcaa aaaaaagata tatagaagac ttaaaaatag aaatggaatt atatagtaat
     2041 aaattatata aagataataa atataaaaat aaagaatgct gtagtctaaa taaaaatgac
     2101 aaaataacga gtatatttgt agggggaggt acacctagta tactaacctc tgatgaaata
     2161 agagaagtat ttataagtat aaaagaaatg tttgatatag atgagaatgc agaaataact
     2221 atagagtgta atcctgggac attaacatta gaaaaattaa aaactatgaa agagattggc
     2281 ataaatagac ttagtatagg gctacaagct attcaagaaa agcatttgaa ctttatagga
     2341 agaatacata cttatgaaga atttgagaaa aactataaag atgcattaag tgtaggtttt
     2401 aaaaatatta atatagattt aatgtacagt cttccaaatc aaactctatg tgattggaag
     2461 gaaactcttg aaaaagttgt acacttaaat ccaacacata tatcagctta ttcccttata
     2521 ctagaagaag gaactgaact atacaatatg tatgaaagta ataaatttga acttatagat
     2581 gaaaatgtag atatagaaat gtatgagtat acaataaact atttaaagtc aaaaggatat
     2641 aatcaatatg aaatatcaaa ctactcaaaa gaaggctata attgtgagca taatatttta
     2701 tattgggaat gtgaacatta tatagggatt ggagcaggag cttctggcta tattaatgag
     2761 aacagataca ataatgtaga atctttagaa gattatcatt taagtttggt aaaaagagaa
     2821 aaaccaatac aagaaaatga aattctttct gagaaagata tgatagaaga aaagatattt
     2881 atggggctta gaatgaataa aggcataaaa tttgaagatt ttaaaaaaaa atttggaata
     2941 gattttagag agaagtataa taagcaaata gaaatgctat tagctagaaa gcttataaat
     3001 cagagctttg aaggtataca attaactcaa aaaggaagag aaatatctaa tagtgtattt
     3061 atagaattta tggaataatt tttaaggtgt tgacaaaata aatttataat ggtatataat
     3121 atatataatc tttttagcac tcgaacttag tgagtgctaa cagctaggag gtataataat
     3181 atggaattaa atgaaagaaa attaaatatc ctcaaagcta tagttaaaga ttatatagaa
     3241 acagctgaag ctataggttc tagaacaata tctaaaagac atgatttagg tgttagtgct
     3301 gctaccataa gaaatgaaat ggctgacctt gaagaattag ggtatttaat tcagcctcat
     3361 acttctgcgg gtagagttcc atctgaaaaa ggctataagt tatatgtaaa ctctcttatg
     3421 agtaaaagcg aattggatga taatgataag attcttattg aacaatgtat gaatcataat
     3481 ataaatcata taaaagaatt gattcatgaa acttctaagc tattatcgca actaacaaac
     3541 tatacaactg tagcagttac taagagttta ataaatcaaa gtgttataaa gcacatacag
     3601 ttggttgcta tgaatgacaa taatatttta cttatagttg taacagataa aggggactta
     3661 aaaaaagcta accttacaac taatgtatat ttagatcaat ctaagttaaa tttgatttct
     3721 gataatctta caaggaagct cttaggtaaa agtataacag atttggatga taatctaatt
     3781 gcttttatta aatacgaaat aagtgagtat tctgggctta tagatgagct tttaaatgct
     3841 ttgaactcaa atatgaaaga agaagatttt tctctatcat taaatggagc tactaacata
     3901 tttagttatc cagaatttaa tgatgtatta aaagcaaagt catttttaaa tatgttggaa
     3961 aaaaaggaaa caatagctga cataattaaa tcaaagggaa tacaaaaaga caatctaaat
     4021 ataataattg gtagtgataa tgattgtgaa ctggcacagg attgtagtat agttacagca
     4081 acttataatg tagatagaga cttggttggg cgaataagct ttataggccc taccagaatg
     4141 gattatgcta gaatttactc tataataaat tatatgagtt tattaattaa tagaaagtaa
     4201 agaaatttta aattgcgagg tgtaaagtct tggataaaaa aaatgagcaa caggaagtaa
     4261 gagaagaaaa tgatacttct attaaccaag aatcggaaac tcaagtagag ttagaagagg
     4321 aagttgttaa tgaagaatgt gaaacatcaa gtgaaaaaac tgatgaaaaa gaagttgatg
     4381 atgaaaatgt aacagatata aattctaagt tagcagaaaa aaaattgcag gatgagttgg
     4441 atgaattaaa tgataaatat caaagacttc aagccgaata tgcaaactac agaagaagaa
     4501 ctcaacaaga gaaagagaca ataggcgtat ttgcaaatga aaaaataata actgaattga
     4561 taccagttat agatagtatg gaaagagcct tagatgcatg tgaagataag gaagatacta
     4621 tgtataaggg tataagcctt gtacataaac aattaataga cactttagta aaatttggag
     4681 tagaagaaat agaagcagaa tctaaggaat ttgaccctaa tctacatcta gcagttatgc
     4741 aagaaagtgt agatggagtt gaagcaaatc aaatagtaat ggtacttcaa aaaggatata
     4801 agctaggaac taaagttgta agaccttcaa tggttaaagt ttcttgctaa gtataaatta
     4861 aaggttaaat tatttaacct aatataaaat attaaaataa gtaaaactta attatataat
     4921 tactcgagga ggattttagt catgggaaaa ataataggaa tagatttagg aacaacaaat
     4981 tcatgtgttg cagtgttaga aggtggagaa gcacaaataa tagcaaatag tgaaggtatg
     5041 agaactactc catcagtagt agcatttaca aaagatggtg aaagaatagt tggagaacct
     5101 gcaaaaagac aagcagttac aaatgcagat aaaacaataa cttctataaa aactcatatg
     5161 ggaactgatt ataaagtaaa tatagatgga aaatcatata ctccacaaga aatatcagca
     5221 ataatattac aaaaattaaa atcagatgca gaaagttact taggacaaac agtaacagaa
     5281 gcagttataa cagtaccagc ttactttaca gatgctcaaa gacaagcaac taaagatgct
     5341 ggtagaatag cagggcttga tgttaagaga ataataaatg agccaacagc agcagctctt
     5401 gcttatggta tggataaatt agaccaagaa aagaaaatat tagtatttga cttaggtgga
     5461 ggaacttttg acgtatctat acttgaaata ggagatggaa cttttgaagt tttagctaca
     5521 gctggtaaca atagattagg tggagatgac tttgaccaaa tagtaataga ttatttagca
     5581 gaggaattta aaaaagctga aggtgtagat ttaagaaatg ataaaatggc tcttcaaaga
     5641 ttaaaagaag cagcagaaaa ggctaagaaa gaattatcat caacaatgag ttcaaacata
     5701 aacttacctt tcataactgc tacagcagaa ggaccaaaac acttaaatat agatttatca
     5761 agagctaaat ttgaagaatt aactagaggt ttagttgaaa aaactatgga accaactaag
     5821 acagctttac aagatgcagg actttctaca ggtgatatag atgatgtatt attagtaggt
     5881 ggttctacaa gaataccagc agtacaagaa gctgttaaga agtttatagg aaaagaacct
     5941 cataaaggta taaacccaga tgagtgtgtt gcagcaggtg cttctataca agctggagtt
     6001 ttagcagggg atgttaaaga cttattatta ctagatgtta ctccattatc tcttggtata
     6061 gaaactatgg gtaatgtaat gactaagata atagaaagaa atactacaat accaactaag
     6121 aagtctcaaa tattctcaac tgctgctgat aaccaaacag ctgttgatat acatgttctt
     6181 caaggtgaaa gaagtatggc ttatgacaat acaactttag gaagattcca attaacagat
     6241 ataccaccag cacaaagagg aatacctcaa atagaagtta cttttgatat agatgcaaat
     6301 ggtatagtta atgtttcagc taaagattta ggtacaggaa aagagcaaaa aataactata
     6361 acatcaaaca ctaatttatc agaagcagaa atagagcaaa agataaaaga agcagaaatg
     6421 aatgcagaag ctgacaaaca aaagaaagaa aaaatagaag cattcaatca agctgaatct
     6481 actatatatc aaactgaaaa aactttaaat gaacttggag ataaaataag ttcaggtgaa
     6541 aaagaggata tagaaaaagc tatagcagac ttaaaagctg taaaagataa tcaagatgct
     6601 acagcagaag aacttaagaa agctacagat gaagtaatga ctaagttcca aaaagtatct
     6661 caagaaatgt accaaaaagc agctcaagaa caacaagcgg cacaaggtgc agaacaagca
     6721 caagacaatg gacctaaaga tgacaatgta gtagatgctg actttaaaga agtagatgaa
     6781 gataaataag ctatataata tgtaacacta aatgataatt ggaacatata tgatttgtga
     6841 aaatcatata gatgttaaag atatatggac aatatacatc ataaagaata taatatatca
     6901 tagattatat aacttaaagt agaatataag aattaatgat agcttgtagt ttattattct
     6961 acaagctatc gttttgtaaa atgaaggtgg tgtcaatttt tgagtacaaa aagggattat
     7021 tatgaagtct taggtatcag taaaggtgca gaagctcaag agataaaaaa agcttataga
     7081 aaattagcaa tgaagtacca tccagataga aatcctggag ataaagaggc ggaagaaaaa
     7141 tttaaagaga taaatgaagc ttatgaagtt ctatctgatg atacaaagag aaaaacttat
     7201 gaccagtttg gacatgatgg gctaaatggt caaggcggtt ttggtggtca aggaggattt
     7261 ggcggtcaag gctttggtgg ttttgaagat atgttcggag atatatttgg tgacatgttt
     7321 ggaggaagct tcggaggtgg aagagcaaga agaagagggc ctcaacgtgg tgcagatata
     7381 agacagagtg ttactatatc ttttgaagaa gctgcatttg gtaaaaagat gtctataaaa
     7441 gtaaatagaa gtgaagaatg tgaagaatgt aatggaactg gagcaaaacc aggaacatca
     7501 aagaaaactt gttcaacttg taatggaact ggtcaagtta gaactgttca aagaactcca
     7561 tttggtaata tagcaagttc aagaccatgt agtgcttgta atggaactgg agaagtgatt
     7621 gaatctccat gtagtaaatg tcatggaact ggaaatacaa gaaaagttaa gactatagaa
     7681 gtagatatac ctgctggtat agatgatggt caaatgataa aactttctgg tcaaggtgaa
     7741 gtaggagaaa aaggtgctcc aagaggagac ttatatattg tagttaatgt taagtcacat
     7801 ccactattta ctagagatgg aaatgatatt tattttgaaa tgccaattac atttgttcaa
     7861 gcaactttag gtgatgagat agaagtacct actttggatg gaaaagttaa atatagtgtg
     7921 ccagagggga cacaaactgg aactgtattt agacttaaag agaaaggaat ccctagaatt
     7981 agaggtaatt caagaggaga ccaatatgtt aaggttgtag ttgaaattcc taaaaaatta
     8041 aacgataagc aaaaagaact attgagagaa tttgcgaagg agtgtgggtc gaacgtccac
     8101 gaaaagaaga aaaccttcgg acaaaagata gaagatatgt ttaagaaaaa gtagttaaag
     8161 tagccaatat ataatcatat ttttaaaatc ttagttattt ataagattgt caaaggagat
     8221 attatgattt ttatattggc tatttttgta taaaaaataa atgtgcataa aataaaactg
     8281 aatataaata attttctgaa aaatacttgt cctaaaatat ataatatgct ataatataat
     8341 caaataaaag aaaggggtga ttccagtggg aacggatgtg gcactgccaa atgatgaaga
     8401 aaactttatt gtaatataca aaataaaatt agatactttt agtgctagat taagtactgg
     8461 aaaaactcat gagctgggat aattattgta attacctaga ctcaaacttt tagtagtaaa
     8521 atagtaatat tatatagaca aggtatctaa tttttaaatc ttttgtatga attaaaattt
     8581 ttataaaggg tatatctgat tagaatgtaa ttagggaaac ctagttgtga attactttta
     8641 gtatatacat gtgtaaagaa atatgtatat ggtattggtt attgtgctag atgtgtatgt
     8701 aaaggaatat gtgtctagtt gggtatatgt aaagaaatat acttataatc tatgaaaaat
     8761 ttttagtata aattgctaaa acattgagat tgttttttat agaaagttag tttataccaa
     8821 ctaaaaatgt gcttaagatt tgtttgatgt ttaattataa ataaggttgt agataaaaaa
     8881 ataagtaaag acaaaggttt aaaatacttg ctttaaatat agtttgtttt gaacacttgc
     8941 caaattaaaa taattaataa aatagacatc ttctcatagt aaaatatact gtgagaggat
     9001 gtttttgctt tgttcataaa cttttatgaa aaatttgcat agtgtcacat tttaatatac
     9061 tatatatata ataaaatata gataaaatta aatgattcaa aagagaaagg tgaaaagaga
     9121 tgtattatat aggtgtagac ataggaggaa caggtataca agcaggagta gttgataact
     9181 atgggaaaat aatttttagg tcagagtgta aaacagtaat tgaaaaaggc tttgaaggaa
     9241 tacttaatga cataaaaata atgatttata agttgttgga agataataaa cttactatga
     9301 gtgacataaa atctattgga tttggtgttc caggttttat aaataaagaa ggattagtaa
     9361 cttgtgtaaa tttaaaatgg aataaaaaag cttttaataa agagttaaaa agaagatttc
     9421 cagatgttga aattcatgga gaaaatgatg caacagtagc agcacttgga gaagcaaagt
     9481 ttggaagtat gaaaggtgct aatgttggag tattatatac tttaggaact ggagtaggtg
     9541 gaggaatagt aattaatcaa aaagtctttt ctggagcaca tggattgggt tcagaaatag
     9601 gtcatcaaat tataggagaa aactatttta attgtaattg tggaaataat ggttgtgtag
     9661 aaactttttg ttcagcaact gcaattataa agtattctca aaaactgata gaagaaggag
     9721 aaaagagtag gattttagat ttggcagagg gaaatttaga aaatgtaaat gcaaagatgg
     9781 tgtttgatgc atatagagaa aatgatttag tggcaattaa agtaataaat agatttaaag
     9841 agtatttagc aaaaactttt gcaaacacaa taaattcttt agacccagaa attatatcta
     9901 taggaggagg catttctaaa tctagcgata taatacttga tggaatagaa gatttggtaa
     9961 gaaaatttgt attatacaaa acagaagata tagctacaat tacatgtgca actttaggtt
    10021 cagacgcagg aattatagga gcagcttttt tataatgtaa atgaactgct tattggaggc
    10081 gtgatgatat atgggtaaaa caaatgctag aagaacgctt tttttgatag caataggttc
    10141 aggaactatg ctgaatcctc ttaattcttc tatgatttca cttgctttac atagtataca
    10201 aaatgatttt catattagtt ttacaactgt atcttggatt gtttcagcat tttacctagc
    10261 tagtgctatt gcacaaccag tttcaggtaa gataggagat ttaataggta gaaaggtctt
    10321 atttttgagt ggtttgatgc ttgtaatttt atcagcatcc atagtaccac ttgttcaatc
    10381 attctttata ttgattttta taagagtaat tcaagcaatt ggaacaagta ccctatatcc
    10441 atctggagtt gctcttatac aaaataatat aaaagaaaga caatcttctg cattagcagt
    10501 tctaaccatt tttgcttcaa ctacagcagg attaggtccg acacttggag gattattgtt
    10561 ggacttagga ggatggcatg ctatatttct tgtaaatata cctgttgttt tggtttctat
    10621 atgcttaggg tattttttat tcccaaaaga agtaaaagaa aagaaatcta taaaagaaac
    10681 tttaaaaaat gttttgtcaa gattagatat tattggcata cttctatttt caattgcaat
    10741 gatttttata ttactatttt tgctatctat gaaggagtct tttaacttgg aacaacttgt
    10801 atttggtata atactgatgt gtctttttat ttggcatgaa ttgagaacaa aattgccatt
    10861 tatagatatt aagctttttg taagtaatcc taaattgtca aaagtttact tgcaatttat
    10921 tatattaaat ttctttaatt atattttgtt ttttggtctt cctagttatt ttcaagatgc
    10981 cttacattat agtgcaaagt cgactggatt atttatgcta tttatgtctg gtataggtat
    11041 atttatatct ccattaactg gaaaatggat agataaatct ggaactagat ttcctcttgt
    11101 tacatcatca atctttatgt ttattagtgc agtacttctt tcagtagttt ttatccatat
    11161 acctgtaata ggaaagggta ttatattatc attagcaggt attagttatg gagttggtaa
    11221 tgtagccctg caatcctcta tgtttgaaga aagtcctcgt gacagtatag ggacagcttc
    11281 tggtctgttt caaactagtc gttatttagg ttctatttta gcaactgttt tacttggaat
    11341 ggtatttgaa gtaaatataa catcagaaca atttcagata ttaggttatg ttatggtggt
    11401 cttaggtaca ataagttttt tattaaattt tatattaaag aaagaattaa gaaaagtaga
    11461 atagtggatt tatggattta ataagtctaa taactgataa gtttaaaaat attgtttgta
    11521 aaacataact ggtttgatat ttattaattc taagttttga agcatagagt actcgataag
    11581 tatacaatat tttgaattaa aattaagcag aaatttgaac tagtctttca aatctctgct
    11641 taatttagta gttaaatttt tttatagaga aaataagatt tgacacttag ataaaaaatc
    11701 attgcatttt caaaattctt taaatcaaac ccaagtatct cattaatctt ttccaatcta
    11761 tatactagcg tgtttctatg taaaaacata ctagtagatg tcttagaaat atttaaatca
    11821 ttatttataa attttattcc tgtatataga agttcttcgt caatagattt aatcttatta
    11881 aaatctatta atttattgag tatattatcc tcattaatta aatctaaagt tttatatcta
    11941 ataaagtcaa acaaatttaa aaacttattt tcagcgttgt cttttataat atgaggtagt
    12001 aaatcagaac ataactgtaa tctaaaatca aaatcagctt tactatctaa ttcaccaaga
    12061 taaaaaatat aagtactttg ataagtttca gtttcaatta tattttgtgt agttacatta
    12121 atatctaagt tatatttaga atttactata aaaaaaccat tgtgttgtat tatatttata
    12181 tcttcaaata aattataaaa aatatttttt agatattcaa agtctatatg agattggtaa
    12241 attaaataaa agttgccttt taaattatcg agattatttt tatctagaaa atcaataaca
    12301 taaatagcat tattgaaagt aactaaatgg ctactagcat ctaacttttg gttttcatat
    12361 ggatagatat ttattttttt attaagctgt ctttctaaaa aatcttttaa ctcttccata
    12421 aagtctcctt aaaaataaga ttatattctt atcttatagc taaagtagtt tctttgtcaa
    12481 atatgtgtac tctactattg tcaactgaaa gtgttaagtc atcaccaaca ttaattctgt
    12541 ttttactgtc aaatctaatt gttatcgtat tttcgcctag ttttaagtga gcataagttt
    12601 ctgctcccat aagttctttt atttcaattc ttgatttaaa acaagtatct ggattagatt
    12661 taataaaagt atcttctaca tgaatatctt ctggtctgat acctataaca acttcattat
    12721 taatataatt gtcttttatt aaatcatagt gtttttcttt attcaattta agcttaatat
    12781 gttcattttg tgcataaatt tcatcatttt cttctattaa tattacatca ataaaattca
    12841 tctgtggtgc tccaataaat cctgcaacaa atatattagc tggataatcg tatacatctt
    12901 gtggagttgc aatctgctga actactccat ccttcattac tacgattcta tcagccatag
    12961 tcatagcttc aacttggtcg tgtgttacat agataaatgt agttccaagc tgttggtgta
    13021 gcttagttat ctctgttctc atagcagttc taagttttgc atctaagttg gatagaggtt
    13081 catccattaa gaatacctta ggatttctaa ctattgcacg tcctaaggca accctttgtc
    13141 tttgtcctcc agataatgtt ttaggttttt tatttaaaag aggtagtaag tctaatattt
    13201 tagcagcttc tttaactttt ttgtctattt catctttagg caaatttcta agtttaagtg
    13261 caaatgccat gttttcgtaa acagataagt ggggatataa agcatagttt tgaaaaacca
    13321 tagctatatc tctatctttt ggttctatat tattgacaag tttatctcca atgtatagtt
    13381 ctccttcaga gatttcttca agaccagcaa tcattctaag tgtagtcgat ttaccacaac
    13441 cagatggtcc tactaaaacg ataaattctt tatctttaat gtctatattt atatttttta
    13501 ctgcgttaaa tccatttgag taaagttttg atatattttt taaaattact tctgacataa
    13561 tatcctcctt gatatttaaa ttttaattat atagtatcaa atttttttat tatattaaat
    13621 gtgtaaaatg actaaatgta tttgtttaat atgtatattt agtttttagc aaagaataaa
    13681 actaacagta gaatatattt aaaaaattaa aaaacaaaat taaatttatt atcaaaaaat
    13741 cattttatga tatgttttat ttttatatta caaatagaga ataatgaatt atactagaaa
    13801 gtaggaggtg aaaatatgag cagaatttca atttttatgg aatcatgtaa tggcaaattt
    13861 ccaaatgaaa attcaatgtt gtcagtttcc tttataaaaa atattttaaa tgcagaaaac
    13921 aaagattttg ctaaaaacat atttaactat ggggaagaaa gaaaaaacaa taagcaaata
    13981 aaggatataa atacagccat ttacatacca aatcttataa gaagcaaaaa tgagttactt
    14041 gttgatggag atataatatt caatataagt ttttataatt attctatgtt cagtaaatta
    14101 tacaatggaa ttttaaaagt aaaggagcta gaatataaag gttatagatt taaaataaaa
    14161 aatataaaaa tacataaaga acacgagata aaagaaaatg gtgttatatt taaaactatg
    14221 tctcctataa tagtaaagaa taaagaaggt aaatatttag atgtagaaga ttcaaattat
    14281 atagaatgtt taaactatat agctaatcta actctggaga gtataagagg tagtgggctt
    14341 agaaagccat tggaatttat acctattaac ttcaaaaaaa gagtgttaaa agaaaagatt
    14401 cgtggattta aagtgagaga atattactat ataaatgctt atgcaggaac atttttttta
    14461 aaaggagata tggaagattt aaatgcactg tataaaatgg gaattggata tagaaggaca
    14521 gaaaatgcag gaatggttga tatattaaag tagcgaggtg agagaaataa aagctaaatt
    14581 ttatagatca ggtgatattg taagagatat tggcattgtt tacttttatg aattactaat
    14641 ggatttaaaa aacgaactag aaaaaaatga ttataagcta aaatttactt gtgagttaaa
    14701 tagaaattat ttatctttag aatctgcaga atatatagac cctaagtata tatctgatta
    14761 tatattagaa aatcgacttt ttaaggtatt taaaaatggg aaaaaggaaa ccttagaaaa
    14821 aatatttagt aatatagata atttaacgta tgtaaatttt attgaagaat tagataaatc
    14881 ttctgcaact gctaaacaaa aggaagatat taaaaaagat tttaaaaaca ggaggtttcc
    14941 atatgttaga aatagtggta agtatggatt aaacacgagt ttagaaaata tggaaacaaa
    15001 tgtaaaaaga atagtagata ctgtaattaa atcaaatata gagatagatg aaatagataa
    15061 acttgatttg acacaatatg aagaaaaaga tagtgtatgt aatgtttgca atataaataa
    15121 aacaacaaaa ctagatattg atttaagaga acgaaaggac tctaagtata actttttatt
    15181 tagaggtgca gaaaaatcag gctttaaaag aagtggacaa gttgaaagta atatttgttt
    15241 tgagtgtgaa tttttcaact taatgtgtct tttatatata aatttaaaaa gaccaatggt
    15301 ttttgcatat acgaatgatt taagagaatt agcattttta aatcataaga taatgcttaa
    15361 aagaaaaatg tattcagata aatcatttta taaaaaactt ttgcatgaaa aaataagttc
    15421 aattagacta tatagctttg atattgatac gaataaaggt ataattctaa agtttgattc
    15481 tattatagag tataaagaat tattaaaaaa aattgaactt atagatatta tagataatta
    15541 taatttttca agagagccag gtaatactag aaatttgggt aaaagaatga ttgataatgg
    15601 gaatttatca aatttaaaag aattattact tgataatata agtgttttaa agcaatcaac
    15661 tggaacttct cgagaaatgg attttgtatc tagctcatat aatatcggtt tatatataaa
    15721 attgtgttgg attgtagatg gaggggagga gtataaaatg aaaaactata tggaaagtaa
    15781 tttaatatat tcaagagtag gtaaagactt atttaataaa atgacagatg aatccagaag
    15841 aaaaaatttt tctatgaaag tgattcaact acttaagtct aatgatagaa ctcagctatt
    15901 tcaaactata atgcatgtgt tagtttctaa tggaatctta ataggagaag ggtttgtaga
    15961 aggtctaatg cagagttctg aattagaatt aaatacgaat gtaggtctat ttattcaaga
    16021 aatcatgaaa taaaaaaggg ggaaaattta aaatgaatga aaaaagagta aaaggagtaa
    16081 cattaactat actgacagaa agcccagttc cactttcata tgaccaaggg tatggaaatt
    16141 atacaccaat aaaaaaagaa caatatagag aaaaaataca tgcaaaaact agtatagcca
    16201 caataacata tgatttaaga agaatgctcc accaagaata tggttggaat ttaagtaata
    16261 ttgtttttgg aaaaaaagga aatatatatc catctattaa gaaaaatgta ggatgtgtag
    16321 atgaaaatgg attagagact gatgtatttg gttatttaat accacttaaa gataaaggtt
    16381 ctataagtaa agcttctcca cttagaataa taccttttag gtcattaaat ccatataaag
    16441 gttcaacaca gctaataaca aatagaggct ttttaagtag tgaatttggt agaaaatatt
    16501 atgatgagaa ggaagaaaat gaagtaccta gagatgaaaa ctttccaaca tcacaagcat
    16561 tagcaataga agagacttta tcagattact acgtttatac aataacattg gagcttgata
    16621 gaataggagt agtagaagta gaagatggaa agttactttt accagaagaa agaaaattta
    16681 tgagtaagga gttaagagaa aaagcagtaa aagatatatt agatgcaatt actgtgttta
    16741 caagaaacat aaaacattca tcagtactat taaaaccact tgcagtaata ggtggagctt
    16801 ttgataaagt tgtaccattt ttttgggatg atgtagatta taatgctgat agtggtgaga
    16861 taaatttaga gggagtcata gaaactatag aaagttatag ccttaaagaa agtaacacaa
    16921 tacttgctat caatgataga ttaaaaattt ctaataaaaa ggaattaaat aagtttaatt
    16981 taagtaaata ccctgtaaaa gagattaaaa atctagcaga tagattggaa attggagaag
    17041 ataatatgtg gtatttaaaa gagtaggagg ttttttgaat tatgaaagta ttacaatgta
    17101 aacttaagca accaactgct cactatagag acccaaaagt atttcaaaat gaatatataa
    17161 gtactttaaa tttaccatct aagaccacaa taatgggaat gataacgtat ttatgtgata
    17221 gaagattaaa ctctgatata gatataggaa taattggaac acatcatcat agagaactag
    17281 aattttcaag aggagaaaac attgattttt ggaatgaata tataaaaatg ggaaaaggta
    17341 aagataaaga aaagtttttg cttaaaggaa actactatga ttactataaa gagcataaag
    17401 ctcaaaatag catattaaac tatgaagttc ttaaagaagt agaactgact atatttattt
    17461 cttgcaagga tgatgaagaa cttgaattta ttagaaaaaa gcttgaaagt ccatgtaaat
    17521 atgcaaattt aggaagaaaa gaagattttg taataccaag tgaaaaaggg tgttttgtga
    17581 aagaagttaa gttaaaagag gttataccta tgaatactcg tgatgctata aaagaaaata
    17641 taaaattaaa gaatacatat gtaagagttg acttaagaga taaagagaat gtcgagacta
    17701 taataaatca aggtgtattg attgcattgc ctcataaata taaagattta gaagcaaata
    17761 gagatgatag agtttatgag ttttgccatt atatatatgt tgataatgat ggtatatatc
    17821 ctaaaaatat taaggtaaat gtatgtattg atacaaaaga agtttttaca tggctttaaa
    17881 ttattttgaa agataggtgt ttatcatgaa aaatatcatg caaaaagaaa tattagctaa
    17941 gtcatacaat ttaagaacta atcaacaaga acaaacatta gttgaacata ttaaggattt
    18001 atttgaagta ttagaatcta tattagaatt aaatctatat tcagataaag atgtagagat
    18061 actaaaaata tgttgtgctt tgcacgattt aggaaaaatt aattcaatta tgcaacaaaa
    18121 aatggagatt aataataaaa tatcgtatag ttgctcagaa gaagagagga aaaagttaga
    18181 gtctgacaaa aaatctttaa aaaagatagc aagacataat atattttctg gagcattttt
    18241 aaaagatata ttagaaaaaa tgaacttgtc agaagaagat aagttatata tatataaaag
    18301 tataatgtta catcatggaa actatgaaga ttatatgagg ttaagtatta gtaaagttca
    18361 agaagaaatt tatgagtata ttgaaaaagg cattttagaa aaagaagagt ttaatctgaa
    18421 agatatagaa agttatataa atagcatttt aaatgtagac tttaaatttg gtgaagatgt
    18481 attggattat gattacatag ataaattaag tgaaagtatg tttatagaca gtgattataa
    18541 caatggtcaa atagatgatt cagttttaaa ttatagaaag tttaagtata ttttatataa
    18601 agggatgctg aacttaatag accatagtgc atcaagtaga cagaaaggta taaaatttta
    18661 taacgatttt actgatgaag aaattgataa tatgatttta aatgagatat ataagagtca
    18721 gggtaatttg gaaaaaaata atatagagtt caatactata caaaaaaggt tgagagaact
    18781 ttctggaaga aatgttctga ctgttgcatt tacaggttca ggaaaaacag ctgcagatta
    18841 tagaaagact tttaaaagaa aattcttttt agtgccaaat aaaatatcag cagaaagttt
    18901 ttatagaaaa aatatttttc aaaataaaaa tgatttagat acaagaagta gtaatgatta
    18961 cattggatta cttcatggag atataaactt atattcagag aatgaagata atggagaaca
    19021 tgattttgta ttgacattaa gggatataga tttgagtata aacttttgca aaccttgtgt
    19081 aattgcaaca gttgatcagt tattacttag tatgtttaaa tttccgggat atgaaaaaat
    19141 attcgcagcc gtaaaaaatg catctataac tgttgatgaa gtacatttat tggaaccaaa
    19201 gatgtttttg attttgatat attttatgca gtttgcatgc aagtacttag atgttgattt
    19261 tcacttaatg acagctacac ttccaaaatc atataaagag caaatgataa acaagggaat
    19321 tatttttcaa gaagaaagta atgaaaatgt tactgataaa ggagaaatag tttttattga
    19381 gagcaacaag gaagaagaga tttgtgaagg taaagatgta aaggtttctt ttataaagga
    19441 aaaagaaatc aagtcaatag ttgaagatgc tttagaaaat aaacaaaaaa ttcttataat
    19501 aaagaatact attgattcag tcaatagaac atatgagttt ttaaaagaaa atttatctga
    19561 taagtatggt ggtgtagata tagatgtttt acatagtaga tttaagttca aagataaaaa
    19621 agagaaatat agtaaaatat taaatggaga gggtgatatt tggatatcaa ctcaatcagt
    19681 agaaatatcc ttggatttgg atttcaatat aataataagt gatttagcaa ctatggatag
    19741 cttaatacaa agaatgggta gatgcaatag aaataataag tatgaatatg gaaactttta
    19801 tattctacct agtgaagata aaatttatga caacaaactt aagagcacaa ctaaaaacat
    19861 cttaaaggac atattaaaaa ctaactctat ttttacaatg ggaattagaa aaactatttt
    19921 ggatgattac tatgataata gtgtagtcaa aaaatatttt gaagagaatt ttataagttg
    19981 tgataaagaa attaagaata tttatggtgt aaataaagaa atttttgatg gattggattt
    20041 aatttttaat tttgaacctt acaaaaatat tgttgatagt aagaaggaag cagctaaaat
    20101 ttttagagat gttgatgtta gttacaaaat tattctggaa gaagattttt ataaggaaga
    20161 tagagagtta caacaagatt cgattcaagt atcagggttt atatttaata gattatatta
    20221 ttatgggtta ataagcaaag tagaaggata catggtacta aaatctagta gtaagtttga
    20281 gtataatagt actgtaggct taattttgaa gtgagcatat gtttaaatat aatatacctt
    20341 tagacattga aaatacaaaa agtactactg taagctcact gtaaaaacta ttttttaaaa
    20401 ggaaaaataa gttgtgagat agagtgttta caagtgtata tagataataa atttgaggtt
    20461 taagattaac taagtgggtt tcaggtacat cgcgaaaata attataagtt ggagattttg
    20521 tatgtttaag attaactaag tggatttcaa atattgatat agtagatata atagaagttt
    20581 tattattagg tttaaaatta actaatcgga tttttaaata ttctgactat tatataagga
    20641 tattattaga ttgaatttaa aaccaataat ataaaacaac aaaatattat atttatgata
    20701 taataaaagt tatggaaaaa caggaatatt actatagaga agagaggtaa acttatgaat
    20761 aattggatag aagtaactat aaaaacaaca acagaagcag ttgaacctat aacgaatata
    20821 ctatatgaac aaggagctgg aggagctgta atagaagacc caaaagactt tttattccaa
    20881 aagaaaaatg aactagactg ggattatgtt gaagaagaag tatttaaaaa gaatgaagaa
    20941 gatgatgttc ttataaaaac ttatgtttct gaagaaaaaa atgtgatgga atttgtcgaa
    21001 ataataaagc aaaaagtttt aggattaaaa gattttggta tagatatagg tgaaggaagt
    21061 gtatcattgg accaagtaaa tgaagctgat tgggcaaatg catggaaagc atactacaaa
    21121 ccaacaaaag taggacaaag ggtagtagta aagcctacat gggaagatta tgctatgcaa
    21181 gagggggatt taatcataga gcttgaccct ggaatggcat ttggtacagg tacacatgag
    21241 actactagta tgtgcattag agaattagaa aagtatgtga ataaagattc taaagtattt
    21301 gatattggat gtggtagtgg aatccttgca atagcagcag ctaaattagg agcaaaagaa
    21361 gttgtagctg tagatttaga tgaagtggct gtaaaagttg caaaagaaaa tgttcttgaa
    21421 aataaagttg aaaaaagtgt atctgtaatg catggtaatt taactgatgt aataaaagat
    21481 aaagcggatg taatagttgc aaatataata gctgatataa taaagatact tgcaaaagat
    21541 gttcaaaact ttatgaaaga agatgctata ttcatatctt caggtataat tttggataaa
    21601 gtagaagaag ttaaagaaag cttaattgaa aatggatttg aaatagttga agttcaaaaa
    21661 ttaggtgaat ggtcagcaat agtttctaag cttaaaaaat aagggatatg gtgacgtata
    21721 atggatagat tttttgttga aaaaaataat ataaatctac aagataaaac ttgcactata
    21781 gaaggtgaag atgtaaaaca tatttcaaaa gttttaagat gcaaattagg tgagaaactt
    21841 gaaatatgtg acaagaataa taatgagtat atttgtgaga taatgaatat agataagagt
    21901 atagttaatt tagaaatttt agaaaaagtt gatataaata gagaatcaga acttaaagta
    21961 aggctatacc agggacttcc aaaagctcca aaaatggaaa taatacttca aaaattaact
    22021 gaagtgggtg tagaagaaat aatattagtt caaactaaga gaagtgttgt taaagttgat
    22081 gacaaaaaag aagataaaaa atttgaacgt tgggaaagaa taatttatga agcagcaaag
    22141 caaagcaaaa gaggtaagat accaaaatta agaggtgttt taagttttaa agaagcttta
    22201 gaagatatga aaaaaaatag tgtaaatatt tgcccttatg aaaatgaaag aacagtttca
    22261 ataaaacatg cactaaaaaa atgtgattct aatatagata gtgttggaat ttttataggt
    22321 ccagaaggtg gattttctga agaagaaata gaacaaatac aaaaaaataa ttgtaatgtt
    22381 gtatcattgg ggcctagaat attaagaact gagacagctt ctgttgtagc atcaacaata
    22441 gctttgtatg aactaagtga tttaggagga gaaaaataaa ttgaaaaaag tagcttttta
    22501 tacacttggg tgtaaagtta atcaatatga aacagaagct atgctagaac tatttgagaa
    22561 agatggttat gaacaagtca atagtgaaga gtatgctgat gtttatgtta taaatacatg
    22621 tacagttact catatgagtg atagaaaatc tcgtcaatat ataagacgag ttaaaaagaa
    22681 gaatccagat gcaataatag ccgttgtagg atgttattct caggtatctc cggaagaaat
    22741 tttggatata gaagaagtaa atttagtcat gggtacaaat gatagaagaa agattgttga
    22801 agaaattaaa aagataaatt caagtaagaa agttagtaca gttgatgaca taatgaaagt
    22861 taaagctttt gaagaaatag aaatcagcca aactaatgga aagactagag catttatgaa
    22921 aatacaagat ggatgtgaca gattttgtac ttattgtatc attccttatg cccgaggacg
    22981 cgttagaagt agagatattg atagtatagt cgatgaagtt aaaaaattgg ctaataatgg
    23041 ctataaagag gttgtattaa caggaataca tgttgcctct tatggaaaag atttaaagga
    23101 tagggatatt aaacttcttg atgtaataaa acaaataaac cagatagaaa aaatagaaag
    23161 aattaggctt agttctgttg aaccaatttt atttacagat gaatttgtaa atgaagtttt
    23221 aaagatggat aaagtttgtc ctcattacca tttatcactt caaagtggat gtgatgaaac
    23281 tctaaaaaga atgaatagac gatacacaac tttagagtac aaaactattg tagatagatt
    23341 gagaagtaaa atgccagatg tggcaataac tacagatgta atagtaggtt ttcctggaga
    23401 gacaaatgaa gagtttaaaa aaacgtacga gtttttaaaa gaaatagagc tttcacaaat
    23461 gcatattttt aaatattcac caagaaaagg aactccagct gcaactatgg aaaatcaagt
    23521 tgaccctcaa atgaaacact ttagaagtga acaactttta aatttaagta aagtaaattt
    23581 taataaattt gcaactaaat ttatcggccg tgagttggat gttttatttg aacaaaatat
    23641 agaaggcaat aaatatgagg gattaacttc aaattatata agagttgttg ttgaaagtga
    23701 caaaaatata caaggtcaga tattaaaagt gaaaataaat gatgtaaaag atgaatatgt
    23761 agaaggaatt ttgctataac atgtagaaat tataatattt ataagatagg aggtggaaag
    23821 aatggattgt attttttgta aaatagcgaa cggagaaata ccttcaacta aagtttatga
    23881 agatgataga gtcttagctt ttaatgactt gaacccagtt gctccatatc atatattagt
    23941 tgtacctaaa aaacattatg atagtttaat tgatattcct gataaagaga tggacattgt
    24001 gtcacatatt catgttgtta ttaataaaat agctaaagag aaaggttttg accaaactgg
    24061 attcagagtc ataaataatt gtggaagtga tggagggcaa gaagttaaac atttgcacta
    24121 tcatatttta gctggtaaaa agcttcctaa ttacgaagcg ggacaaaact aaactaaatt
    24181 attgaaaaat tgagttcctt cttgataaaa atacttgata aaagtaaaaa tttagtttat
    24241 aataaacaaa gtgttaggtt gtaatgcata ttatgcaaaa agaacatagt tacagtccca
    24301 gcataattgc gctattggag ggagggaaaa agaaatgtca gaagtaagag ttagagagaa
    24361 tgaaacatta gacagcgctt taagaagatt caagcgtcaa tgtgcaatgt ctggcatcat
    24421 gtcagaagtg agaaaaagag agcactatga taagccaagc gttaagcgta agaaaaaagc
    24481 tgaagcagca agaagaaaaa acgctaagaa atagtagtaa ataagaataa agaggtgaag
    24541 gggatgtccc ttaagcaaaa gttacaagag gatttgaaat cttcgatgaa aaacaaagat
    24601 acagtgagaa aatctgtagt aactttaata agagcttcta taaagcagta tgaggttgat
    24661 aatagggtcg agcttgatga agatggaatt atcgatgtaa tagcaaaaca attaaagcaa
    24721 cgtagagatg cattagttga atttgaaaaa gctggaagag aagacttaat aaaagaaaca
    24781 gaaggtgaaa ttgaagtttt aaaagagtac ctacctcaac aattaagcga agaagagtta
    24841 gaagaaattg taaaatctac tatatccgaa gtaggggcaa cttctatgaa ggatatggga
    24901 aaaataatgt cagttatcca accaaaagtt aaaggaagag ctgacggaaa acttataaat
    24961 aagttggtaa aacaaaactt acaatagatt gatatagcct agagagaaat ctctaggctt
    25021 tttatagttt ttgggaataa cgagtcatat ttgagcatat ctataatcaa agaaaatttt
    25081 gaaagaaggg gaaaaatttg attatatcag taaaagagat taggaatttt ttgataaaca
    25141 tatttatacc actaataata ggttacttaa gtagcatctt aacaatgatt atcagtggaa
    25201 cagatatttc aacctattat ttacaactca caaagccaag ctttgcacca ccagctttta
    25261 tctttcctat agtttggact atattgtaca tattgatggg tatatcttca tacctaatat
    25321 taagaaaggg ttacaactta cctaaagtaa gagatgcaat tttttattat ggattacaac
    25381 ttgtattaaa ctttatttgg agtatactat tttttggatt tggacttaga tttacagctt
    25441 tgatagatat aataataatg attttggttt ctataataat gatttcgaag ttttctaaaa
    25501 tagataagag atctggatac ataaatttga tttatttaat gtggcttgtt tatgcaggat
    25561 ttttgaacta ttttatatgg tttattaata aatagaatgt aaagattttg taaattaccc
    25621 tgtactttta ataatatcat aacaaacgaa aaataaatag actattaaaa ataatcattt
    25681 tcatatacaa taatattaat ttaaatacaa taaatttata aaaattgtat ttaaagatta
    25741 acatattaaa gtattagaat tggaaaggct tgaagggaga ggtttttatg caaataatag
    25801 tatctgggag acaaatgaaa ttaactgacg gaataaaagg atacgtagat ggaaaattaa
    25861 gtaggttaga aaaatacctt gatcctgaat cagaagtgaa agtaacagta agtgcgaaaa
    25921 aggatagaca aaaagtggag gttacaataa ttcctattaa cggtcaaata ataagagcag
    25981 aagatgtaga agatgactta tatgcagcaa ttgatattgt ttgtgacaaa ttaagtagac
    26041 aagttgtcaa atataaaact aaagttaaag acaaagttca aaataataag agcataagat
    26101 ttgaaaatct tgactttata gataatagca gtgaatttga tgattatgat tatgatgatg
    26161 aagaagatga aaatatagta atagaaagaa gaaagaaatt taatgtaaaa cctatgagtt
    26221 ctgaggaggc gatacttcaa atggaactag taggacacaa tttctatatg tttagaaacc
    26281 aagataattt tgaaataaac atagtgtata agcgtaaagc tggtggatat ggtttaatag
    26341 aacaagatta ataaaaattg tatacgttta gattttatat aagaaaaaat aaaaaggtaa
    26401 tcatgttgat tttttatcaa tatgattacc tttttcttgt ttaaataata tattagatat
    26461 taggtattta ttatataaaa attttaaaac taatctgtta caacatcaat aaagtgcata
    26521 aatacctatt tcaagcataa aattaattaa gggggtaatg cttatgttag aaatatccac
    26581 tgatttacaa gtaaatcaac cagttattac tgttacaagt aatacgttta ttagtataga
    26641 aaattatcta tcaatattag aatatgaagt tgatttaata agaataaaga ctaaagttaa
    26701 aacaattaaa atatctgggg ataaactttc acttaagtat attactgata gtgagatagg
    26761 tataaaaggg attatctaca atgttgagta tgttgattag gaggagatac acttgataag
    26821 ttttataagg ggatactatg ttatagttgt ggaaggagta ggactcgaac aatttttaaa
    26881 tcatcttata agaaatggga taagtgttta caatgtaact agaataaaaa atactaaaat
    26941 ggagtttcat atagatagac aagatataaa agactttaag aatgtttata gaggaagtaa
    27001 gtttgatata aaggtaaagc aaaaaactgg ggtccctttt attatcaaaa gagtttataa
    27061 gcacaaaggt atgtggattt gtgctcttgt ttctttattt ttattgatgt ctacatcaca
    27121 gtttgtgaca gatgtatata tacaatctcc tgaaggtata aaaaaagaag ctcttagaaa
    27181 tgagctttat aaggttggag taaggccagg agtctataag aagagtattg atagaaaaga
    27241 agttagagac catatgatgt caaaatttaa tgatgtggca tatttatcta tcaatgtaaa
    27301 aggaacaaat atatttgtta ctgttacaaa aaaggcagaa tccctaaaat ctacagacca
    27361 atcaaattat tgtaatgtaa ttgctttaaa aaatggtata atagaaaagg taatccctag
    27421 aagtggtaaa tcagttatta aatctggaga catagtccaa aagggagatg tcttattaaa
    27481 tggagctaat accaagtcaa taccagaagt atgggcaagt actttttatg agtccacaaa
    27541 aaaggcaagt tatgtagata ctgtaaataa aaaaactgga gaaaagaaaa atatatatac
    27601 actaagtttt tatgataaag agtttacaat gagaaaaaat ataaaatata aagattatgt
    27661 tgttgaaaat aaagaaaaaa aactatcaat aggaaactat acttttccaa taaagataaa
    27721 aacgagtact ttttatgaaa caaaaaaggt tgaagtaaaa aggaataaag aagagttaaa
    27781 aaaagaatta tctgaaaaag ctttaaaaga gttagaatac ataatcccag cttcggctag
    27841 aataatagat gtaaaacata actttaaggt taataaaaat atgttagaat atttaataac
    27901 agttcaaact agtgaaaata ttgctaaaat ttatcctctt agtaagtcag aagcagaaag
    27961 gtttataaag gaagaaagta aaccagatga aggtgaagag gaagttcctt ccaatccaga
    28021 aaaaagacca ttaaatgata taagaaatga gtttgatgag gataataagg ataataaaga
    28081 ccaaaacaat tctgatgaaa ataatagtaa tcaaaatagt aataatagtc aaaataataa
    28141 tagcaataac aactaataaa attaaactta aaatcttagg aggactaatt caattgataa
    28201 tacaaaagaa atttacaata gcagatggta actttgaaag agagttattt ggcaactttg
    28261 atgaaaatgt aaaattaata gagaagactt taaatataga tgtaatactt agagaaggca
    28321 atataatttt aattggagaa gaaaaaaatg tagattctgc attaaaactt atgaatgaat
    28381 tacaccaaac tgtatcaaat ggtaagcatt tagataagca gagtatttct tattcattat
    28441 ctcttttgct tgaaggaagt gaacaaaaaa taaaagaact tgaggggaca atcgtcataa
    28501 ctcaaagggg aaaagctgtt caacctaaaa ctttaggtca aaaagaatat ataaaactta
    28561 tagaaaataa tgatataact tttggtgttg gacctgctgg aacaggaaag acttatcttg
    28621 cggttgctat ggcagtaaaa gcttttaaaa gagatgaagt tagtagaatt atacttacaa
    28681 gaccagctgt ggaagcagga gagagtctag gttttttacc aggagattta aaggacaaag
    28741 ttgacccata tttaagacca ctatatgatg ccttatttga aatgttgggt gctgataaat
    28801 ttaataagta tttagaaaga ggtactattg aggttgcacc acttgcattt atgagaggta
    28861 gaacacttga taattcattt ataatattgg atgaagctca aaatactact tctgaacaaa
    28921 tgaaaatgtt tttaactaga cttggatttg gctctaaagc tgtagttaca ggagatgtaa
    28981 ctcaaacaga tttaccacaa aataagaaga gtggtctaat acaagctaca gagattctta
    29041 aaggtgttcc aggtattggg tctataatgc taacagatag agatgttgta agacatgagt
    29101 tggtacagag aataataaga gcttatgaga agcacgacaa aagagaagaa tttaaaaaag
    29161 aagaacgtaa aaaagcgaaa atgcaggaaa agactttcaa aagaaagtaa aagtgtagta
    29221 atatagatat atagcattat taatgaataa aaagtaggtg tagtgaatgg atttgatact
    29281 agatgataga caagataaat tagaagtaag tgaggagtta attgaaaaga taaaggatat
    29341 aatcatagaa tgtttagatt atgaaggata tgatgataat tatgaagtga gtctttcttt
    29401 tgtagataat aaagagattc atgaattaaa tagagaatat agaggagttg atagagtgac
    29461 tgatgtttta tcatttcctc ttttaagtga tgattttgaa gatgttgagt tagaagaaga
    29521 atccctaggt gacatagtag tatctcttga aagagcctta gaacagagta tagagtataa
    29581 ccatagtttt gaaagagaag tatgtttttt aatatgtcat agtatgtttc atcttttagg
    29641 ttatgaccac gatacagatg aaaatacaaa agaaatgaga gaaaaagaag aacacatatt
    29701 aaataagtta aacataacaa gggagtagtt tttatgaaac cagaaaaaac tcgtcaaggt
    29761 ataattaaag catttaatgc agctatagaa gggatattgt atacatttaa atttgaaaga
    29821 aatatgaaaa tacattattt aggttcagtt gctgttctta taataagttt gttttttaac
    29881 ttttcaaaat tagaaatgat aatgttactt atgtccatat gtttagttgt agttgctgaa
    29941 atgtttaata cagctataga aaaagctgtt gatttagtaa ctgatgaata tcatgttctt
    30001 gctaagatag caaaagatgt tgcagctgga ggcgttctag tggcagcact aaattcagta
    30061 gtagttggat atattttgtt ttatgataaa ttgacagata tatctggaat attaatttat
    30121 aaaataagag aatcagaatt acatataacc ttgatatgta tattattggt tcttatagct
    30181 gttgtagttg taaaagcatt gacttctaca ggtactcctc taaaaggagg aatgccaagt
    30241 ggtcatgctg ccttagcatt tgctatagca actgcaatta cacttatgac tgaaagagtt
    30301 gttgcctcta ctcttgcata tataatggct gtattagttg cccaaagtag aattgaagga
    30361 aaaatacata cattttggga gactattgct ggagctttgt taggtgtgtt gatagctata
    30421 ttagtatttc agcttggaat gttctataat taaaataaat gtacataaaa tatttaaaat
    30481 aaaacaaatc tgtgctaatt aaatttttat gatataatgt agagtattaa ataaaaataa
    30541 cttttaatta ttgtatacag gaggagttgt tgtggataac atagaattgt taaggttggc
    30601 agaagatgcc agacaacatt cttatgctcc ttactcaggt tttagagtag gtgcagctct
    30661 tttaactaag agtggtaaag tttatactgg atgtaatata gaatgtgcat cattaggtgg
    30721 aacaaattgt gcagaaagaa cagctatttt taaagcaata tcagagggtg ataaggatat
    30781 ctataaaata gctatagcaa gtgataactc agaaaataat gagcaaacat atccatgtgg
    30841 aatatgcagg caggtaatta tagagtttgg ttctgatata aaaataataa cgggatatac
    30901 taaaggagag gtgtttgagc atagtataaa ggatttgttg ccaaactatt tctctggaaa
    30961 tgatttaaaa taaatttaaa agtataaata aatttaagta attaaaacaa gaagataaaa
    31021 agttaggaga cagttaatgt tcaaatcagg ttttgtcagt atagtgggta gaccaaatgt
    31081 aggaaaatct actttaatga ataatgtagt tggagaaaaa atagctataa tgagtgataa
    31141 gcctcaaact acaagaaata caatacaagc agtatataca gatgaagaaa tgcagatagt
    31201 attcttagat acaccaggta ttcacaaacc aaaaaataaa ttaggtgaat ttatggtaaa
    31261 ggcagcaaca gaagctttta aaaatgtaga tttaatatta tttgtagttg atgattctaa
    31321 aaaaataggt cctggagata gaaagataat agaggattta agaagtgtta agacaccaat
    31381 aattttagtt gtaaacaaaa tagaccaact agaccaaaaa gatgagctat ttgatataat
    31441 caaaatgtat gatagagaag gtatttttaa agaaatagta ccaatatcag cattaaaagg
    31501 aaagaatacg gataccttaa taaaagttat acaaaattat ttagaagaag ggccaaagta
    31561 ttttccagat tatatgatta cagaccagcc agaaagagta ttaatagcag aacttataag
    31621 agaaaaagtt cttcactatc ttaatgatga aatacctcat ggtgtagctg ttgaaattga
    31681 aaaaatgaaa gcgagaaatg ataaggaaat agtagatgta tctgctgtaa tatactgtga
    31741 aagagattca cataagggaa taataatagg aaaaaatggt aggaaactaa aaggaatagg
    31801 taagtcagca agacaagata tagaattgct tttaggttca caaataaatc ttcaattatg
    31861 ggttaaagtc aaggaaaatt ggagaaattt acaaaattat ataaataatt ttggatataa
    31921 tgataaataa aggtgggtta tatggatagg aaactggatg cttcccaaga tttattatat
    31981 gaagtaaaat cattaattga taataataaa gtattggagt taagagaatt aatagaggaa
    32041 tatcatataa ttgatatatt cgatataatg gaaaatttag aggaagacat gaaaattcaa
    32101 ttatttgaag tacttccttt agatatggca tcttctatat tagaagaagg tagtgtagag
    32161 ttttttatta gtattttatc taaactggat gtagaacact cgaaaaatat acttgaactt
    32221 atgtctcttg gagatatggc agacaagttg agtgaacttg aagaagaaga aagagaacac
    32281 ataataaatc ttttgaatca agagaatgcc gattatgtaa aagagttact attctatgat
    32341 gaagattctg ctggtggaac aatgaccact ggatatattt ctataaataa agatatgaca
    32401 gctcttgagg ctatagacca tatgagagaa gaagctgaag aagctgaaac tatttattat
    32461 atatatgtgg ttgatgatga agaaaaacta gttggagtat tgtcattaag agaattaata
    32521 atagctagag acgcaaatat agtagaagat ttgatgagtg aaaatataat ctctgtttat
    32581 gtagatgaag atagagaaga agcagtaaga ttagtatcta aatacaattt aatagcaatt
    32641 ccagtagtag acagacaaga aaaattaaaa ggaataataa cagtagatga tataattgat
    32701 gtaatggaag aagaagcaac tgaagatatg tataaatttg caggaagttc agaacatgaa
    32761 agagaagttg cggaaaaaga aaaccctaca ttgagagagc aaataatatc agcacttaga
    32821 ggacgattac cttggttaat tattacctta gttggagggt tgttggcttc gttaatactt
    32881 tctaacttag actatataat gaatcctgta tatgctccat tagtattttt tatacctgta
    32941 gtaattggta tgggtggaaa tattggaact caatcatcat ctgttacagt aataacattg
    33001 tctaataagg atttaaattt tagcaatgtg gttagagaag gtattgtagg tattattaca
    33061 ggtcttttgt gtagtataat aacaggtatt gtaatttact ttgttatgag aaagttagac
    33121 attgtattaa ttgtttcaat atcattattt ataaatatgg ttttaggtgc aacaataggt
    33181 gcgtttatgc ctgttttatt aaaaaaaatg gatgcagacc catctacagt ttcatcacca
    33241 attatatcta cagctcttga tataactggt atagcagttt actttataat aacaacggca
    33301 ttattgtcaa aaattgttta ataactttat gtatgattta tcctcttctt actaaaaata
    33361 taagtataaa tgtaagaagg gggtttttta aaaatgaaca atatcagttg ggaagttttt
    33421 aaaaaaacag gtagtataga tgcatattta tatttctgtg attgcaaaaa catacatgaa
    33481 gaaattgaag aagtaaggga gaaaaaagaa gacgatgata atcctgaaca cccaggggat
    33541 agtacttaaa gctataaggt ataaggaaag tgatataata cttacactat ttacaagaaa
    33601 gcttggaaaa gtatctgcaa tagcaaaagg agctaaaaaa aataagagct ctttgctttc
    33661 atcatcacag ttattttctt atagcaattt taccttaaaa aaacaaggta atatgtacaa
    33721 ggttactcaa agtgaaataa taaaaagttt ttataatata tcctatgata tagaggcatt
    33781 ttcttatgct acatatatta caaaattagt tgaaaattct atacttgaaa atcagactaa
    33841 taataggcta tttatattac ttgcgcagac tctgtatttg tatacacagg ataatacaga
    33901 caataggttt ataacagcag cattcgagtt aaaattttta gactatatag gatttaaacc
    33961 tatagtaaat aaatgcatta attgtgaatg taaaatttta caaaattctg tgtttaatat
    34021 ctacgaaggt ggtatactat gtagtaagtg tagtaaactt tttgataata atataaaatt
    34081 agacttaaca actataagtc ttatggaata tgtattaaga aatgatattt taacatgtag
    34141 taaagctaaa gtatcaaaat atataacaca tgaacttgag aatattctag acaagtattt
    34201 gaaagtttat gttgataata ttaattttaa atcattacac gtattgcaaa gtgtaaaaaa
    34261 taataaggga gtggataatg atgagtagta atataactat tgaaatggtt gattcagtct
    34321 ttgaaagagt tccaggagca acttatgcag aagcaaaaga agcattagta atgtgcaatg
    34381 gagatgtaat tgaggcagta atatatttag aaaataaaaa aaatacttgt aattgtaaag
    34441 caaaatctgc taaagaaact atggaagaag tatttggcaa agatggagaa aatataaagt
    34501 ttcaattaaa agagcttctt agaaaaagta gtgtagtgcg aataatagtt gaaaaagatg
    34561 gaaaaactat gatgaacatt cctttaacag ttggagttgt tggattagct tttgtaccat
    34621 tagctacttt agttggatta tcagctgctg ttataagtaa atatcgtata aaagttcaaa
    34681 atgaagaaga tggagaaatt gtagatttag gtgaattgaa tgaagaaaaa cttcacgttt
    34741 tgaagaatat gataactaat gcagcaaaag atgtgaagga tgtagtagtt gacaaaaaag
    34801 aagatgacaa agatgtaact gctgacctta tgaaagaaga atctgaaaag aataaagaag
    34861 acgaagacga aaataaatag atataaagtg acttttaaaa aatgaagaga agataattat
    34921 aagaattatc actaacattg acaaatttta tagaatttga tattctaaaa gttgtagaag
    34981 aactattaaa atagcctttc gtgtagacga gaggctttat tgttatagga gggattttta
    35041 tgaattttca agagatgata ctggcgttgc aaaaatactg gtcaaagcaa ggttgtatca
    35101 tgatgcagcc ttatgatatt gaaaaaggtg caggaactat gaatcctaat acttttttaa
    35161 gatcattagg acctgagcct tggcaagtat gctatgtaga gccttcaaga agaccagcag
    35221 atggaagata tggtgaaaac ccaaacagac tatatcaaca tcatcaattc caagttatac
    35281 taaaaccttc tccagataat atacaagaat tatatttgga aagtttaaaa gagattggaa
    35341 ttgacccaag tgagcatgac ataagatttg ttgaagataa ctgggaagct gctacagttg
    35401 gtgcttgggg acttggatgg gaagtttggc tagatggtat ggaaataact caatttacgt
    35461 attttcaaca agtaggtaat attgaatgtg agcttgagac aggagaaatt acatatggat
    35521 tagaaagatt agctatgtac attcaagaag ttgatagtgt ttatgattta aaatggaatg
    35581 ataaaataac ttatggtgaa gtatttaata aagctgagta tgaaaactca atgtacgcat
    35641 ttgaattatg tgatgcagat atgttgttta atctgtttga tatatatgaa aaagaagcat
    35701 taagacttat ggaaaatggc cttgtaatac cttcatatga ctatgtgtta aaatgctctc
    35761 atgcatttaa tacattggat gcaagaggtg caataggagt tagtcaaaga gcttcattta
    35821 taggtagagt tagaaatatg gcaaagactg ttgcagaaac ttttgtaaaa caaagagaag
    35881 aaatgggatt ccctctttta aaggacggtg acaaataatg aaaaattatc ttttatttga
    35941 aatcggtgtt gaagaaatgc catcaagatt tgtaggcagt acactagaac aattaaaaaa
    36001 caatcttagt aaattatttg atgaaaatag aatagctttt gataaaataa atgcgtatgg
    36061 gacaccaaga agacttactt tagtagtcga aggattgagt gatagacaaa atgatttaga
    36121 agaggaaata aagggtcctg ctaagaaaat tgctgttgat gcagaaaata atttaacaaa
    36181 accagcatta ggatttataa aaagcaaagg attaagcgaa tctgacatat attttaaaca
    36241 agttggaaaa gaagaatata tatttgcgac tataaagcaa gatggaaaag aaacttcaga
    36301 agtactaaaa gacatattac cagagactat aaaatctgta gtattcccaa aagctatgcg
    36361 ttggggagga aaaaatctta aatttgcaag acctataaga tggatagttg cattgttaaa
    36421 tgataaagta ttagagtttg atttagaagg aataatatct tctaatgtaa caaaaggtca
    36481 tagattttta ggtgaaagta caatagaagt tgattctata gaagattatt ttgaaaaatt
    36541 agaaaaaaat tatatagttt tagaccaaaa caagagaaaa gaaatgataa gaaaacaatg
    36601 tatagaagtg gcaaattctt taggtggaga agttgaattt gatgaagatt tacttgaaga
    36661 ggtaacttac ttagttgaat atccaactgc tttttatgga gaatttgatg tggattatat
    36721 aaaactacca aaagaagttg ttataactcc tatgaaacaa catcaaagat attttccagt
    36781 acttaaagaa ggaaaactgt tacctaactt tatagctgtt agaaatggtg attcttacag
    36841 aatagacaat gttaaagctg gaaatgaaaa agttttagaa gcaagacttg cagatgcttt
    36901 atttttctat agagaagata ctaagagaaa cttagaaagc tacatagaaa aattaaaaac
    36961 tgttgtattc caagtaaaac taggaactat ttacgacaaa actttaagac ttgaaaaatt
    37021 aagtgctgat atacttgata gtttaggttt agtagatgaa aaggcagata ctataagggc
    37081 tgctaaatta tctaaggcag atttagttac tggaatggta ggagaatttg atgaattaca
    37141 aggttttatg ggaaaagaat acgcaaaagt tggaggagaa aatgatgttg taagtgaagc
    37201 tatttttgaa cattatcttc caagatttgc aggagatata cttcctaaga ctaatgcagg
    37261 agttgcctta tcaatagctg ataagttgga ttcaatagca ggtttctttg ctataggaat
    37321 acaaccaaca ggttctcaag acccatatgc tttaagaaga caagctttag gtatacttag
    37381 tatacttatg gacagaaaag ttgctgtgga tataaaagta cttattgaac atgctttaga
    37441 caattattct gaattagatt ttaataaaga agaagttgtt gagcaaataa tgaatttctt
    37501 caatgagaga gtaaaaaatc tatttaaaga tttaggaata agatatgatg ttgttgatgc
    37561 tgttttaagt tctgatataa atgatgtttc tgatatgcat atgagagctt tagagcttaa
    37621 taattggcta gaaaaagatg aattagtgga gatgcttact gcatttaata gagtttctac
    37681 tctagctcaa aaagcagaaa gtgataaaat tgatgaatct ttattaaaag aagatgctga
    37741 aattaaactt tacaatgaat ttaaacaagt aaaggtaaaa gttaatgaat tattaaagga
    37801 taagaaatat ggtattgctt tagatgaatt tgcatcttta agaccagtag ttgataattt
    37861 atttgataca gttatggtta tggataatga tgaagctatt aagaacaata gacttgcttt
    37921 acttaaacaa gtatatgata ctatgctagg aatttgtgat ttatctaaaa ttgtttataa
    37981 ataaaattta aactatttat aagaaataag gctgtctcaa aatagagata gtcttatttt
    38041 tcattgttga gatgatgaaa atatatttga tttcatagaa aaagagtgtc tcataaacta
    38101 aaaagttcat tttgagacac ccatgctttt tgtaagtaaa tataataaat tatattttat
    38161 acttatcagt tattttgttt aaaatattat catttgaatt tacccattca taaaaattgc
    38221 ctgatgatgc gtccgatatt ttataaagca tttcaggaat atcactagct ttaaaatctc
    38281 caagtgattt tcccaatcta gtcttaccta tttcaaaact gcctccaaca aataattcaa
    38341 atgcatctgt agatatacca tcaacattct tctttttacc acataaacct atgctaccaa
    38401 cttgatgaac accacatgaa tttaaacatc ctgatatata taacttaggt gctttattta
    38461 aaatttcttt attattttgt aatctaaaat aatctatgat ttcatgtaac attttctgac
    38521 tattttgtat gcccatttga caaattggaa cacctatgca agatatactt tgttctaatt
    38581 gagaattaca actaatagtt ttacttattt ctaatattct ttttgcttca tttccattta
    38641 aatttaaaat atataatccc tctgtcattc ctagtctaat cataggattt tcaatattat
    38701 ctaattcttt aagtaaagta cttaaatcct ttgttaacaa aatacctcca actggatgta
    38761 tatatacagt gtataaacca tcctgttttt gaggtattag tctagaatcc tgtatatcta
    38821 ttttaacccc aggtttagag taatctattt cttcaatatt gagttcaaga ctaccatttt
    38881 ctttttctaa tttatagtat tctttaaatt tttctaagaa taatttttca ccaagtgatt
    38941 cgaccatata tctaacccta gctctgtttt tattttcata atttccataa tccataaaga
    39001 atttaatcat accttcaaca caatataagg catctttcgg ttttataagt tcatcaagtt
    39061 ctaaagcaac tttgggttgt ttacctagac ctccacctaa gaaaactctg aaatatggtt
    39121 catcattttt caaagtagca acaaatccta agtcttgtat actacaatga gcagtatctg
    39181 tgtaacaatt agaataagaa acttttaatt ttctaggtaa atggtatgta gtagcatttt
    39241 tgataaaata tttatcagta gcaactgcat atggagtaac atcaaagact tcactagggt
    39301 caactccaga taatggagat aatccgacat ttctaggata attaccacca ccacctctag
    39361 tgaatatatc attttttatt ccttcttcca tgatatcaac aattgaattt atagataaat
    39421 cgtgtaattg tatagcttgt ctagttgtta agtgtatctt atctaagttg tgtttaatag
    39481 ctatttcata gattttatta agttgatact gagataaaac tccagcagat actctaagtc
    39541 ttatcataaa agattttttg tctctttgag cataaacacc atatccacca gaaaatccct
    39601 tatattgcat tttatttatt tctccattta aaaattttga agaatattct ttaaaattag
    39661 gtagttcatt taacaatatc tttttaaaat tatccattat ttcacctcat tgttagtctt
    39721 gtataaaaat atatctattg tataatagat atatatatta ttatctagtc aggataaaaa
    39781 tataacagaa taattctatt aaaagtaaga ataataagga catagtgagt attttgtttt
    39841 tattttacaa attaagtata atatttttgt tttataaaat ataattaaga taaatagata
    39901 attttgtaat tttaatatat aatatttagt agagtgtggg agtagcactt aatatttgaa
    39961 ggaggagttt ttgtatatgg gagaaataat aaatgcatta gatagagccc tagacataat
    40021 tttgctgtta tatcatgaaa agagagaaat gggaataact gaaataagca aggctatggg
    40081 agtatataaa agtactgtac atagaacttt ggttactctt gaaaacaaag gttttgttat
    40141 acaaaatgca gagaatggta agtattggct aggaataaat ttatatgcaa taggtatggt
    40201 tgtgggagaa aaaatgtcat tgactgaaat agtaaaacca tatacgaaaa aattaaatca
    40261 agaatttaac gaagtagtta atgtatctat attagaagaa agagctcaag attctccaag
    40321 aagtatcata atacataaag agtatggttc aaatcaatta ctttcagtaa atccatccgt
    40381 tggttcaagt agtgaatgtt attgttcagc agttggtaaa tgtcttatgg catttaatga
    40441 ttctatagat tttgaaaaat atagaaaaac accaatacac aagtatacag aacatacaat
    40501 tgataattgg gatgatatga tgcttttttt agcaaaaata aaagaacaag gatatgctat
    40561 agatgatgaa gaactagaac atggactaac ttgtattgga gcacctatct tagataaaaa
    40621 taataaagct attgcagcca taagtttgtc aggtccaact ataagaatga gagaagggga
    40681 ctttgagtat aagattaaaa gagttataga aactgcaaaa agtatatctg aactttttag
    40741 atgattttta atctcgataa taaaaatagg ctatatttaa attgttattt gtaaatatca
    40801 gtttaaatgt agcctatttt tctttaatct aaaattaaat attcttaaaa tttaaaatgt
    40861 tattgaaata tataagcgaa tgtgttatct tttaattaag caataaaaat agaacaaggt
    40921 tctatactat agaacaaaat tgatgcatat atagtattta tacaaaatat aaatattata
    40981 tatttaaaat taagtaaaaa tattacataa aggggagatt tgagaaatgg aaaaagtcaa
    41041 gttgagtgtt gaaagatgta agggatgcta tctttgtatt gaagcttgta aaaaagatgc
    41101 aataagtctt tctgactaca caaataaaaa aggctttgta actattaaag tcgatgaaga
    41161 aaaatgtatt caatgtggcg cttgttatac aatgtgccct gatttagtat ttgagatatt
    41221 ataaattatt tttattagag gggagaaaag gtatgcaaag tttattaatt aaaggaaatg
    41281 aagctttagc agaaggtgct atacgtggtg gctgcagatt ttatgcaggt tatccaataa
    41341 cgccacaatc agaaatatta gaaatgatgg catggagaca aaaagaagtt ggaggagtat
    41401 ttatccaagg tgaatcagaa atagccagtg taaatatggt tatgggagca agtgcacttg
    41461 gagcaagagc tatgacttct tcatctggtc caggattttc attaaaacaa gaaggtattg
    41521 catattgggt atcagctggt ttgccagcag ttgtagcatg tgtgcaaaga tatggtatag
    41581 gtgatggatt tataggagct ggtcaagata attattggca agcagtaaaa ggcggtggaa
    41641 atggagatta tcatttaatc gtgttagcac ctaatagtgt tcaagaaaat atggatatgg
    41701 catatgaatc ttttgaattg gctgaaaaat atatgcatcc agtacttata ctttctgatg
    41761 ctacaatagg tcaaatggta gaaccttgta tagcaccacc aatgaaagaa tacgatatgg
    41821 ataaagctcc atgggctgca aaaggaacac ctgtaggaga aaaaaataaa gtaataactg
    41881 atataacata ttttgaagac caagatacat ggcaaaaagg gtatatagaa aaaatgagaa
    41941 aagttcaaga agatgaacaa agatgggaag agatagaaat agaagatgct gaagtggtat
    42001 ttgtggcata cggtatttca tcaagaatag cagaaggtgc agttagagat gctagagcaa
    42061 aaggaatgaa attaggtcta ataagaccaa aaacattgtg gccttaccca agaaaagcat
    42121 ttaagaaatt aagtgattca ttgaagggac ttgtaacagt tgaaatgaac atgatggcac
    42181 agatgaagga agatgtaatt atagcatgtg ataatagatt tccagtatat tcagtagcaa
    42241 cagctcaata tatggcagaa gtaaatcaat taatagattt tgctcaacag attatagatg
    42301 gaaaagctaa gcaagaggag gtattttaat tatggctaaa aaagcaccag caataatgat
    42361 gtgtgaaaat atgttctgtg gaggctgtgg acactctata gtcgatagaa ttattggaga
    42421 agtattaaca gaaatggata tatgtcaaga tacaattata tgttcagata taggttgtaa
    42481 tcatatgttt caatttagta tgaatgtaga tgttgtcgtt ccacctcatg gtaaaatggg
    42541 agcagcaatg gcagctatga aaagagttag accagataaa tatatattta caatagctgg
    42601 agatggtgga gcttatgcaa tagggcttgg agaaactatg tcagctgcta ctagaaatga
    42661 taatgtaata tttcttgtta tgaacaataa tatgtttgca atgacaggag ggcaaatggc
    42721 tccaactact atagaaggtc aatatacagc ttctactcca gcgggtagaa attacgcaga
    42781 tcatggttca acatttgatg ttgtaaaagt tatgggaaat ttagatatag catatctagc
    42841 aagaggaaca ataactaacc ctaaagaaat aaatacaaca aaaagataca tcaaaaaagc
    42901 tctagaaaaa caaaaagaaa agaaaggttt ttgcttaata gaagtgcttg taccatgtcc
    42961 aacaaactgg ggattaaagc cagtagatgc tatgaagaga attgaaaatg aacttgttcc
    43021 aaagtatcca cttggagaat ttattgatta gggaggaaat aatatgttga atgaaattat
    43081 atgtgctggt tttggaggac agggagttct tacagcagga aaaattataa tgtatgttgc
    43141 atataaggca gaaaagaaaa ttacatggtt cccatcttat ggaaatgaga tgaggggagg
    43201 aagtgcaaat tgcaatgttg ttgtaagtga tgaaaaaatt gcaaatcctt gtgtaaaaaa
    43261 tccagatata ctattgggaa tgaacagcgt atcagtagat aagtatgaaa gtttaatgaa
    43321 aaaaaatggt tatatgtttg tcaatgaatc actagtaagt aaggatagaa agtacagaga
    43381 agacattaat gttataaaag tacctgttac tgaaatagca caaaatttag gcaatgaaaa
    43441 agctgctaac atttgcatgt taggtgctat ggtaaagagt ttggatttat ttacaaaaga
    43501 agaatttgaa agtggtatgt gtgaatactt tgaaaatcaa ggcaaaggta aattcaattc
    43561 taaaaatgta gaagcatttg aagctggata cgactacgaa tgaatatttt aaatatttaa
    43621 aataattatt gaaatactta tttttatatg ttagtattta attaataaaa tatagaacgt
    43681 cgttctggac aatgggacga agtctttagg tcggaataca agaacggcgt tctgtataat
    43741 agaactaggg ggtgttaaat tgaaagtttt agtaataaat cctggtggta catccacaaa
    43801 aatttctgtt ttccaagatg aaaatgaaat tttgaaaaaa aatataaccc atacaagaga
    43861 agatttaaaa aatttttcta aagtatttga tgaatatgat tatagaaaac aactgatagt
    43921 agatatttta agtagtgaga atcatagtat aaattctttt gacgcagtag ttggtcgtgg
    43981 tggacttatg aaggctataa aaggtggtac ctatactgtg agtgaagaaa tgattgagga
    44041 tatgagaaat gaaataaatg gggaacatgc atcaaattta ggtgcattat tagctaaaac
    44101 tatagctgat gaaataggag tacaatcatt tgtagtagac ccagtttctg tagatgaatt
    44161 tgatgatgta tcgaggatta caggaatatc agacatagaa aaagcaagtt ggttacatgc
    44221 attaaaccat aaagctgttt caagaaaaat tgcacaaaaa ctagggggaa aatacgagga
    44281 ttataacttt attgtagctc atttaggttc aggaatatcg attgtagcac ataaacaagg
    44341 caaaatgatt gatggaagtg gtggtaggtc tgatggtcca ttttctccag aaaggagtgg
    44401 tggattactt gcatatcctc ttatagaatt gtgttactcc ggaaaatata ctcatgatga
    44461 aatggtcgca aaagtaagtt cgattggggg aatgtacgat tatttaggaa caaaggacat
    44521 gatagaaatt gaaaacagaa tcaaggaggg tgatgaaaag gcaaaactta taatggatgc
    44581 atttatttat caagtagcaa aagaaatttc tatgtatgga gcttcacttt cagggaatgt
    44641 agatagagtt atcttgacag gagggatatc tcactcagaa atggtagtca aaggagtagc
    44701 agaaaaagtt tcatatctag ctccaataga gatagtacca ggagagatgg aaatggaggc
    44761 acttgctcta ggggcactta gagtacttaa tggagaagaa atagcaaaaa cttattaata
    44821 tttaggagaa agagtatgtt aaaagatttt aataatttat tagaagaggc taaaaagctt
    44881 gaacctgtta ttgtaagtgt tgctgttgca gaagacaaag aagtattaaa ggctgtgaaa
    44941 tcagcaacag atttaaacat tataaagcca attcttgtag gagacaagga taaaatagaa
    45001 agtatatcaa gagaaattgg attaaaaggt catgaaataa taggttgtca aaatcccgat
    45061 gaatcagtta aaaaagctgt agagatagtt aaaaataagg aagctaaagt tcttatgaag
    45121 ggattagtaa atacaagtgt ctatatgaga gctatattaa ataaagaaac gggtcttaga
    45181 acaggaagat tattaagttt gcttgcagta tatgaattac ctcaatatca taaacttctt
    45241 tattgtactg atagtggaat aaatgtatcg ccaaacttaa atcaaaaaaa agatataatg
    45301 acaaatgcac ttcttactat gaaaagtata ggcatggaaa atcctaaaac tgcgatactt
    45361 actgcaaatg aaatggtaga ccctaagata caatctacag tggatgccaa cctacttgta
    45421 gagatggaaa aatcgggaga aataccaaag tgtatagtgg aaggtccaat agcatttgat
    45481 gtagcatttg atgcacatgc agcagaacat aaaggtatta aaagtaatat tgctggtgat
    45541 gttgatttat tagtatttcc aaatatagaa gcagggaata tattaggaaa gtcatggctt
    45601 agatttaata aagctaagtg ggcaggtata gttttaggag caacaaatcc gataatttta
    45661 ggttcacgtt ctgacacagc tgaaataaaa ataaattcaa tagcattagc gtgcctagca
    45721 tcacaataag aaattattat taaggaggaa aaagtattat gaaatatgca aaaagaatgg
    45781 atatggtaaa agcttcagct ataagagatt ctcaaaagaa aatagctcag aaggtagcaa
    45841 gtggtggaac tgttatatct tttgctgcag ggcttcctga cccaaattta tttccaatag
    45901 aagagataag tgaaataact caaaaagtac ttaatgaaag gggaaaattt gccctagcat
    45961 atggacctac taaaggtgaa gatgagttgt tagatctatt agtaaaaaga atgaaagaag
    46021 aagaaaatat tgatacaaaa gcagaaaata ttataataac tactgggtca caacaaggga
    46081 tagcattaag tgctatgatt ttattagaaa agggagatgt agtagttaca gaaaatccaa
    46141 gttacttagg tgcaataaat gcatttagac cttatgaatg tgatttttta ggagtagata
    46201 cagatgaaga aggaatggta acagatgatt tagacaaatt attatctgaa aattctaaca
    46261 taaaggtgat atatgtaata ccaacatttc aaaaccctac aggaaaaaca tggtctttac
    46321 aaagaagaaa agattttatg gaagtcgtga ataaatatga tgtcatagta atagaggata
    46381 atccttatgg agaaataaga tttacaccag aacctctacc tacacttaaa tctcttgata
    46441 ctaaagataa agtattgtac cttgggtcat tttcaaaggt attatgtcca ggatttagag
    46501 ttgcttggat gtgtggtaat gtagacatca tagataaggc agaactttta aaacaaggta
    46561 tagatttaca gtcaaatcaa ttttcgcaag tacaagtaat agaattttta aagaaataca
    46621 acttaaatga acatatagaa aaaataagag cagagtataa gaaaagatgt ctgctaatgt
    46681 tagatgctat gaagaaacat ttcccagagg aagctaaata tacagaacca gatggaggaa
    46741 tgtttatatg ggttgaactt cctgaaagta taaatgtaga tgatttatta gataaagcca
    46801 ttgatgctgg agttgcttat gtttctggag agtccttctt tgcaaataat ggtccaaaaa
    46861 atactatgag acttaactat acaacaatgt cagaagaaca aatcgttaaa ggtgttgaga
    46921 tacttgcaga agttataaaa aaagaactca attatgcttg tgaataaata taaaaagtga
    46981 gggtttaaat atgggagaaa aagaaaacgg tataaagttt ggaaagttaa tgtttcaact
    47041 tgttattata gcaatatctt gggaattagt ttatattata ccatttatcc aatatacatt
    47101 atatgatcca atcctaaaag cattagaatg tacaaacact caactaggtt ttctacttac
    47161 aatttatggg ttaggtaata tatttggagc tcctatagga ggctggttag cagatagatt
    47221 tgattataga aagataattt taggttctgt atttcttaat ggagtagtat catttttatt
    47281 tgcatttaat atgaactatc catttgcagt tgctacttgg gtaggttgtg caatcacatc
    47341 attagttatg aactatcctt ctatggtaaa aatacttaga gttataggaa aagataatca
    47401 aggtaaggtt tatggattta atgaagctat ggttggagtt tctggagtag taatgggagc
    47461 aatattctta tatatttata catgctttgc aactcctaca ttgggtatga gatgggtaat
    47521 gatatcttta ggaatattat caatagcaat gtgtccagta ttatggtttg taattaaaga
    47581 tgtagatatt aaagaagaaa gagaagaagc aggtgaaaaa atgtctgctg gtgattttat
    47641 aacagtacta aaatcaccaa atacttggct agtaggaata agtatattct gtgtatattc
    47701 attcacagtt acaatgtctt attttacacc atatataaca tctgtacttg gaggttctgt
    47761 agcattatct ggtgcattag caataataag acagcatggt ctaaaattat ttggagcacc
    47821 atttggagga tattgtgcag acaaattaaa atctcctaca aaagtacttt taccaatata
    47881 tgtatttggt atagcagtaa tagttttatt cctagtatta cctgcatcaa ctccaatgac
    47941 tatattcata gctttaacat ttgtagtagg tatattaggt tacatgggaa aaggtatata
    48001 ttatgcagta caagatgaag taaaagttcc agttaaatat tcagcaacta ctataggtat
    48061 agctgcagct ttaggatttt caccagatgt attccaattt gcattaatag gacactggat
    48121 agatacttat ggcaataaag gttacacata tacatttata ttccaaatag caattctagt
    48181 tattggaata ctatcttgtt tatatatatt aaaggttaaa aagagaagag caagtaaatt
    48241 agaagcttaa atattcaatt tggtaattaa gtatatataa atacaatact tattttgatg
    48301 aatgtgattg tataaataac ataaaaaata tcaatagatt aagttttata ataatgttta
    48361 gagaataaag tataaaaatc aaaatgttat caagttttct aggttttaac ataaagttac
    48421 ccctgaaggt gtaaaattga gtggcaatta ttatctattt tcttacctac ataaacctat
    48481 ttaatttaaa ttctaagaga ttttcaaaat agatggtagt tgtactcaat tttaaacctc
    48541 ataataaata cgaaaattta aaatctaact agatactatt taattatata ttaataaata
    48601 tatattgtac tatttatata ataataattt caggcttttc attatatgta ttccaattta
    48661 tattgtttga ttattattca aacacacgtc gttaaaaatt ttataaattt atgtttagat
    48721 atgattaata ctcttgattt tagaaataaa tatttgtaga ttgtagatta aagataatat
    48781 aaataaatag aaggtagatt ttttagatat attaatataa agattatata aaatattgaa
    48841 atatagctgt ttaaattatt gtctataaat ataaaatgaa tggtggtgag ttaagtgacc
    48901 gatttagtta acaccattaa tggaattgtt tggtcacccg tattagttgc aatgtgtttg
    48961 tgtataggat tatatttttc attgaaatta aaattttttc aaataagaga tgtaaaagaa
    49021 atgtttactc tcttgcttga gggagatagt tctcatgttg gtatatcatc atttcaaggt
    49081 tttgctacat ctatggctgg aagaataggg actggaaata tagctggtgt agctgtagca
    49141 atagcaatgg gaggtccagg agcattagta tggatgtgta taatggctac attaggttca
    49201 gcaactgcat ttgtagaatc tactttagct caaatatata aagatgagca tgatgggcag
    49261 tatagaggag gacctccata ttattttgaa aaaggtcttg ggtggaaaaa gtgttcagtt
    49321 ttattttcaa tagttgcaat aataagttat acatttttta tgcctggtac acaatcaaac
    49381 actttatatc tagcaatgaa tcaagcattt ggattttcaa aaatgacaat agcagtagca
    49441 tcttctattg cattagcgat aataattttt ggaggaatta aaaggattgg tttatttgct
    49501 gaaaaagtag tacctataat gggtggagca taccttatta tgacattagt aataattata
    49561 acaaatatta gtttagttcc agaggctatt gtaacaatgt ttaaatctgc atttggattt
    49621 ggttcagttt ttggaggaat gctaggttca gcaatatctt ggggagtaaa aagaggtata
    49681 tactcaaatg aagcaggaga aggttctggg acttatggtg cggcagcagc agaagtaagt
    49741 catccagcca aacaaggatt agttcaagca ttttctgttt atgtagacac attattaata
    49801 tgtatggcta caggtattat gattgtaata acaggaatgt ataatgttac aggtgtttgc
    49861 acagcactac caggtgtaga accgggacca caatatgtac agagtgcaat aaatacatta
    49921 catccacaat taggtgatat ttttatagca atagttttat tattatttac atttacaact
    49981 ttattagcct tctcatatat gatggagact aatgtatctt acttagtaac tagaattaaa
    50041 gcagaaaaac atgaaaagta cataattaat gtctgtagat ttatgcttat agcatgtgca
    50101 gcaatgtgtt gttttataga accacttaca agctgggcat taggtgatat atgtataggt
    50161 gtattaacat atataaattt aattgccatc tttacactaa aaaaaccagc tataaaggca
    50221 tattatgatt atataagaca gaagaagatg ggaataaaaa ggagtgatag aacttttaac
    50281 cctatagagt tagatataag aaatgctgag ttttgggaaa atagatactt aaaagaggat
    50341 aagcatgagt taaattaaag ttataataaa atataaaaat tactaaataa atttagtggg
    50401 aggtaagatt ggtatgaaag aaagaataat acaagtggct gattcaaaga aagaaaaaat
    50461 tctagggcta tgtcaatctt tatatgatga accagaaatt gctttgcaag aatataaatc
    50521 tgctaaaaaa atatcagaat ttctaagaga agagggtttt gatgttgagg aaaacttggc
    50581 aggtatggct acagctttta aagcaaccaa gaaaaatgga gatggtccta aaatagcatt
    50641 tatagcagaa tatgatgctc ttccaggcaa tggacatgca tgtggacatc atttaattgc
    50701 atctatggga gttggagctg gaatagctct ttcaagtata ctggatactt acaagggaga
    50761 agtaagtata attggaacac ctgctgaaga aactggagat ggaaagcctt acttgataga
    50821 acatggtgta tttgatggct atgatgcagc aatgatgata catccaaatt caaaaacttg
    50881 tgtaacacct gaaattatag caataggagg tctagatttc atatttactg gaaaagcatc
    50941 tcatgcagga gctaagccat ataacggaat aaatgcttta gatgcagtag tactactata
    51001 taataatata aatgcactaa gacaacaatt agtagatgga acgagaatac atggtattat
    51061 attagaagca ggaactgctg caaatgtaat acctgatatg ggaaaagtaa gattagagat
    51121 aagggcaaaa gaacaaaatt actttgatga agtagtagaa aaagtgaaaa attgtgctag
    51181 aggtgctgca atagccactg gatgtgaact tgaattttat cactttgaac caacttgcca
    51241 aggattaaat gaaaataaag ttttggtaga catatttaca aagattatgg aggaatttgg
    51301 aatatatgaa gatgaacaag taatgttagg ttcaacagat atgggaaatt taagtcaaat
    51361 aatgccatgt atacatcctt tgatgaagtt ttctgaaaat ggagaagaac tacatacaaa
    51421 agaatttttg gaggcttcta taaattcata tgcaaaagat agagtaattg atggtataaa
    51481 aatattagct ttaacaggat ttaatttatt tgaaaatcca gaattattga aaaaaatgaa
    51541 ggaagagtag aacttagact atttttaatt atactcttta aaataagaag agtgtctcaa
    51601 aatgaacttt ttagtttatg agacactctt ttttgtatga aattaaatat atttttatta
    51661 ttttaaacat gaaaaagagg cttatctgtt tttatatgac cttttttaac ttgtagcaca
    51721 aaatatcatg aatgattaca attcgaatga taaaatcgat tataagatat ataggagggg
    51781 tacatatgga aactttagaa gtaagaaata ttgaattgag tggtacaaat tatgagatag
    51841 gatacagact aggagaattg gttgctaata tgccagagat aatagaaggt cagattaata
    51901 aatctaatct ggtaagcaaa aaagaagaaa aagagatgat agagttgttt gataaatatt
    51961 gtccaggtct taatgaagaa ttgcaaggtt ttgctgatgc aattcaagtg aattgtaatc
    52021 aaattttata ttatactatg acttatctta aaccaggttg tagtcaagtt gcattagcac
    52081 cagaattaac tgaaaatggg catgtactat ttgcacgtaa tttcgatttc tcacacaata
    52141 tggaggattt tgttttatgt aaaactaagg taaatggaaa atatgcacat ataggtacta
    52201 ccattatgca atttggaaga ggtgaaggta tgaatgaatg tggcttaggt gtaagtcagt
    52261 catcatgtgg tattcctgta ggcaattcag atggtttaag aaaaccagca attgtaggtt
    52321 tacagttttg ggctgttatt agatatttgt tagaaaattg caaagatgta gatgaagcat
    52381 tagaatattt aaaagatatg ccaattgcat acaatattaa tttattgctt gcagataagt
    52441 ctggaaacat tgcacttgtg gagactttag atgggaaaaa agaagtaaat ataatcaaca
    52501 gtttagaaag taaaagagaa tattttttac actctactaa tcatacacat attgataaac
    52561 ttcataaatt agatccacaa tcaatgaaaa attctattca tagatataaa ttaattaaag
    52621 aatatataaa taagtctaaa aaaattggag agaaagagtt aatgaattta ttgtcttcaa
    52681 aatatccaaa tggcttatct tgtaattact ataatgattt ttttggaact ttaaaaagta
    52741 tagttatgga tttaaatata ggaaagttta atattttatg gggtggacta gagaataaat
    52801 gggagagcta ctatttaaaa aatgacatta aatctataac acagaggata aacataaata
    52861 ttgaaaaagc accatctgac ttttttgatt tcattgaata aaaaatgtat ttaattattc
    52921 taaataatta ggacatataa atcaactaaa agtttttatt tatcgtattg aattagttat
    52981 aatattttag tatagtaaaa aatagtgcta ttttacatat ttaaagagtt taagtagaag
    53041 agaggtgcca tattggatta cttaaagtat tttgaaaaag ctgtaatgta tattgagaat
    53101 aatttacatg aaaatataac tgtaaatgat gtggcaaaag aaactggata ttcttattat
    53161 catttaacac gcttatttaa gtctatgttt ggtgaaagtg taggaagtta tataaaaaaa
    53221 agacgattag taagtagtac aaaagaactt ttatatagtg ataaaaaagt gatagatata
    53281 gctattggta gtggatttga atcttcagaa gcatttagca gagcatttaa atctatatac
    53341 aaggttagcc ctatagaata tagaaaaaat agaattgatg tatttgttgg taaaaagaaa
    53401 aaattagagt tagattttat gagacatctt gttggaaata taacgattaa accagttata
    53461 aaagaaatag aaaaaataaa ggtaataggt ataaaggata aagtaatttt agaaaataat
    53521 tcattacctg acttgtggga gaaattcaga aaagtacatc atattgtccc aaatactttg
    53581 ccatcaagga gagtttttgg aatctgtgaa gcaatctctg aaatacacct agttagtgaa
    53641 agtatggagt ttaatgagat aataggactt gaagttaata gttatgatgt gattccaaat
    53701 tcatttgttt caaaaactat taaggaagga aagtatgcta tatttactca tactggtagc
    53761 ttagataatt tagacaaaac ttatgaatat atatggggta cttggttttt aagttcaaaa
    53821 gaagaacttg atataagaga tgattttgaa gtatatgatg aacgattttt aggtcctagt
    53881 aatgtgaact cacaaattga tatttatata cctataaaat aatctataag aaaactaaaa
    53941 gataatttga ttaagaaata gatgttcgta aaagagcatc tattttttat ttttataaga
    54001 tttagataat tttaataata aaagaaataa aaataagttc ttaaatttct aagaagaatt
    54061 tagaatatag tcgaaataag aattgtatat ttctgaaaat tctaattagt acaatttttt
    54121 cctttataaa attgaaaaaa gatgtattta tttatcaaaa atattatatt aaaatgatat
    54181 taataaaaaa acatttacaa tattagcata tagtacagaa aaaagatgta atttgtaaaa
    54241 tttatggtaa gcagtaaaat taaaaattta aagatattat agggaggtta taattttatg
    54301 gaaaacgtta ttacaggtct aagtaaaggt gcagagtggt ttatcggttt gtttcagaaa
    54361 gggggagaac aatttatagg tcttgtttca ggtactcttc caacgctaat tgtattaatg
    54421 gtagctatta actctttgat taagataatt ggtgaggaaa gagttaataa ttgggcttct
    54481 aagctaggaa agaactcttt tacaagatat attctacttc cattagtatc agtatttttc
    54541 ttgggaaatc ctatgtgcta tacatttggt agatttttaa aagaagagca caaagcagga
    54601 ttttatgatg cagcagtttc atttgtacat ccaattacag gtctttttcc acatgcaaat
    54661 gcaggagaac tttttgtatg gttgggaata tctgcaggtt tgactacttt aggtaaagaa
    54721 actactacat tggcattgtg gtattttata gttggtctaa ttgtaatttt tataagaggt
    54781 atagtaacag aaaaaatgta tgcttttcta acaagaaaaa atagagcaac aaataaggct
    54841 taggaggtag ataaaatgga ggagaataaa atattaaaaa tagaaaaggg aacttcaggc
    54901 tggggaggtc ctttgtatat aaaaaaagaa gggaatagaa ataagatact atcaatgact
    54961 gctggcggta tccatgaagt aacattaaaa ataaaagaac tactgggttg tgaaattgta
    55021 gatggattta aaactggagt ttctgatgaa gaagtagcag tagttattat tgattgtggt
    55081 ggaactgcta gatgtggagt ttatccaaag aaaaaaatac ctacaataaa tgtaaatcca
    55141 gttggaaaaa caggtccttt agcaaaattt ataacagaag aatattatgt atcagatgtt
    55201 aatcctaact gtataagtgt tgtagatggg gaagatatgc cacaaaaatc tcaagaaaat
    55261 aaaagcgaaa ataagagttc tattagaaag cctgataatt atgatgaggt taagtcaaaa
    55321 gcacaaggtg aatatgctaa aaagaacata atactttcta ttggtcaagg ggcagggcaa
    55381 gtagtatcaa aattttatga tgcaggtcga gatactatcc aaatggtaat gaataacgta
    55441 ataccattta tggcatttgt aagtatgctt atgggaatta ttttagcatc tggactggga
    55501 gactggattg caagagttat atctccactt gcaggtaata ttggtggatt attgattata
    55561 tcagtaattt gcacacttcc attcttatca ccaatactag gacctggtgc agttatagct
    55621 caagtagtag ggactcttgt aggtacacaa attggtcttg gtgcaatacc agcatattta
    55681 gcacttccag ctttatttgc aataaatggg caagctggat gtgattttgt accagtagga
    55741 ttaagtttgg gagaagcaga accagaaact gtagagtatg gtgttccagc tttattttac
    55801 tctcgtttaa taactggtcc aatagctgtt attattgcat atggagttgc agtatttgca
    55861 ttgagataat atttaatgtc aatataaggc ttggaattaa ttaataaaat tgtaaatata
    55921 aatttaagct agtcaagatt ttttgttaat gaaagactag cttttatact attaattagc
    55981 tgtaattatc gagttagatt aatactaaat tttcctttat taaagtgaaa ttttatgtat
    56041 taatttggtt tcaaatttgt actagaatga aatcaaggag gagatacaaa atgagtgtaa
    56101 ctgagaaaat tccttctatt gaccgcaaga tatttaagat attgattatg tgtagtaaaa
    56161 aagagtttgt gagtattaac tcaatagcaa atgaattgaa tgtcacaact agaagtgtaa
    56221 ggacgtatat aaaacaattg aataaagatt taggtaatga tatagcagta atcaaatata
    56281 taaagggtca aggctataaa ctagaaataa aagatgagca gatactcaat aagattattg
    56341 atatgaatag aaaaaatgta ttttcattaa attcaaaaga agatagagta gagtttatac
    56401 taaattactt gatagaacta gatggattta ttacacttga tagtttagct gatgagatgt
    56461 gtgtaggaag aactacttta gtaaatgatt tccagtatgt agaaaaagtt ttggcttcat
    56521 ataatttaaa cttgattaaa aaacagaata caggtatgaa attaaatgga aatgaacttg
    56581 atattagact gtttatatta aatcagttgt ataaaaactc aaggaaagat ttcagtaatt
    56641 caaagtattt taaaggaatc aaaaaagaag aaatcataaa tttagaagaa aaactattga
    56701 ctttatttaa aaaaaataat ttttatgtta cagatgaaat gttaagagaa gttattaact
    56761 acatagtagt tttagtctat agagtaaaag aagaaaagaa agtaaaagat tatgatgtaa
    56821 agtttgattt acttaaatca tatgatgaat actttattgc tagggaaata aaacatataa
    56881 tatcaggaat gtttgaatgt actttaaatg atgaagaaat tatttattta actataccgt
    56941 tagttagtgg aaatgcacca gcatcagaat gtgctttaaa tagtagtaga attagtaaaa
    57001 acattgatga gttgatggaa aatatattta atcaaatata tgtcgatatg ggtattttta
    57061 taaatgagga tgaattaaga gtaggtctag gatatcatct tagttttact ttaaacaggc
    57121 tattatttaa tataaagtta aaaaatgttt tgttagaaga gattaagcaa aattatatac
    57181 ttccatttaa attagcacaa atagcaggaa aagtaataga gaaaaagtat aacttagaag
    57241 tttcagaaga tgagattgga tatatagcaa tccatttcag tggatattta gaaagaaata
    57301 gcagtagatt ctattcaata aaaaaaatag caattatatg tagtacaggt ctaggaacag
    57361 caaaactatt gaaaataaga gtagaaaaac tgataggaaa taatcctaaa attgatactc
    57421 tttcaagttt taatttgaga aatattaact tagatgaata cgatatagtt tttacaacta
    57481 ttgatttaga cacatcaaat ataaatacaa tagtattaaa aataaataca atatttgatg
    57541 aaaacaaact aagagaacaa ttaaaaacag tattgtgcct aagagaaggg aatattgaca
    57601 ctactaattc tacaaattta ctaataaata atttgttaga tgaagataaa tttatgatat
    57661 taaatgaaaa gactatactt gcctcattag aaaaaatgat ggaccatctt atggatttgg
    57721 gatgtattga tgagaagttt agaaaaaata tagtcaatag agaagaaaaa tctcccacag
    57781 tatttgataa aggtttatta tttcctcatt ctataaatga aaaatcagat aagtttttaa
    57841 tggcagttgg aattttagaa gaaccaatag aatatgcaaa tagaagtata aaaataattc
    57901 ttatgacaat gtttccatgt gagaataaga tagactcaga cttattagta aaaatttatg
    57961 aagaagtttt aaagataggc caagatgtaa aattaacgaa taagataagt aaatgtagaa
    58021 cttttttaga atttaaaaag gtgttactta aaaaccttat ataactattg tacagcattt
    58081 atagttgtta tacagattta aaaataatgt gatttttgga aggtgtataa atatgaaatt
    58141 attagtaatt ttatttgttg cttatatttt aaatactata tttataatga agcagaataa
    58201 attgtatttt aaaactttaa atagagctaa aaaaaagggt gatatagtgt ctacaggcaa
    58261 aaagaaaagc tatttttcta aaggaagtat agccgttata tcttcagatt cagatgggtt
    58321 tataaagttt ggagaaattt taaaagggcg tacagtaatg gctaaattta aagagattga
    58381 agaaatagaa ggattagata tatatagtgc agagcaaaaa tttaaagatg aagagagtat
    58441 tgtacaagct ataaaattta taaaagaaaa aataaatgtt tcttttaatt aactcaatat
    58501 aaatataaat tatcaggagg aatgtcatga aatatgaagt taagataagt gggataggca
    58561 gtttagttaa agagttaatg gatgaaagca attgtcttat tatatatgat gaaaccatta
    58621 atgatgacga cttaaaggat atatctgtaa ttcattcaat agcaacatta aaaagtgatg
    58681 ttgaaatagg agatacactt actataggga atagagatta ttgtatagtt tcagttggtg
    58741 atattgctca gaagactctt agagaaattg ggcattgtac aatcaaattt gatggaaaat
    58801 gtgaagtaaa tttaccagga gaaatacatg tggaaatagg aaatccagat ataactattg
    58861 gagatttaat aactatttct taatttgaaa ataaaattat tataacagga ggaattggta
    58921 tgttagattt aaacagaaaa cttgcaaaat tggaagagga aggtaaaaaa ataaaagtag
    58981 ctcttatagg agctgggcat atgggaaatg gaatggtaag ccaaatggca aatatgaaag
    59041 gtattgaagc ttctattgtt gtagatatag atttggagtt ggctcataaa gcttttactg
    59101 atgcaggaat agatgaagaa attatagata atgtaacaaa tgaaaaggat gcagaaataa
    59161 aattacaaga aggaaaagta ttgacatgta atgactttct tgtggcttgt aaaactaagt
    59221 caatagatgt agttatagat gcaactgggg gtattgcaat tggtgcagag atagcattaa
    59281 actctatttt aaataaaaaa catatagtta tgttaaatgc tgaaactgat tgtgttgttg
    59341 gaccaatact taaaaaatta gcagatgatg ctggagtaat atttacaggt tctgcaggag
    59401 atgagccagg tgcagtaatg gaattatttg attttgcaga tgcaatgggg tttgaagtta
    59461 gagtgatagg taaaggtaaa aataataaat tagatttaga ttgtaatcct gatacagtta
    59521 gagaagaagc agaaagaaaa ggagcttcac ctcatatgat agcttctttt aaagaaggaa
    59581 ctaaaacaat ggtagaaatg gctttaatgt gtaatgcaac tggatttgtg cctgatgtaa
    59641 gaggtggtca tggtattgaa gctacagtta atgaagtacc taagaaatat gcattaaaaa
    59701 gcgaaggtgg agtattagat aattatggtg tagttgattt tgtaaatggt atagcacctg
    59761 gagttttcgt agtagttgcc cataaattaa aagcagttaa tgatgaacta aaatatttaa
    59821 gtatgggtga tggacctaat tacatattat atagaccata tcatttatgt agtttagaga
    59881 ctcctttatc agcagctatg gcagttttag accataaggc tacaatagta cctaaagctg
    59941 gactagtagc agaagttatg actatagcta agaaagattt gaaaaaaggt gagtttatgg
    60001 atggctatgg agcatataca tgctatggta ctatagaaaa atacgatgta gcaaaggcta
    60061 tgaatgctgt acctattggt ttgataagta aaaagactaa agttgtaaaa gatattaaaa
    60121 aaggtgaagt tataacttac gatatggtag agatagaaaa agatactact ttatatcatt
    60181 taagacaatt gcaagaaaaa atatttgggt aagatttgat ggtaatataa atagatatta
    60241 gtaaaaaggg ttgatggtta tttttaaatc aaccctttta aatttttata tattcttgtt
    60301 aggatacttt ctttaaaagt atattatagg ttatttgtag tcgtaaaaat tattttgaat
    60361 tagttctgca attttatatt cacattgaaa taatattatt aaaaatttta atataaaatg
    60421 aattaaaatg accaattatg tattataata ttaactgtaa tactaatata gttctattaa
    60481 ttaaagaaat atcccccatt aatatataat aaatatcttt aagcgagaga acttagtaaa
    60541 aaatatatcg tattcaataa aaaatctgtt tacagaatgg tatatatagt tatataatat
    60601 actatataag atgcgaaaag ataaaaagta tagcacaatg aaagaaggtg attattattc
    60661 agcttaatga aagacaacta aaaattatag atatagttaa ggaaaatgaa ccaataacga
    60721 gtgaaagtat tgcctccagc ttgaatgtga ctcgtgctac acttagatct gatttagcta
    60781 tattaacaat gacaggaata ttagacgcaa gaccaaaagt tggatatttt tattcaggag
    60841 ttagtgaaat aaatttaatt ggtaaaagtg taaaagaaaa aacagtagag gatataatga
    60901 gcatgcctgt actagctaag aaggatgaaa gtatatatga tgtaatagtc actatgtttt
    60961 tatctgatgt agggagtata gttattatag atgagaatga agagttatgt ggagttgttt
    61021 ccagaaaaga cttgctaaaa gcaactatag gaggttctga tataaataaa atgccaatag
    61081 gtatgataat gacaagaact ccaaatgtag tcactttaac taaaggagca agtgttttat
    61141 tagcttcaag aaaaataata gaacatgaag tagattcgat tccgattgtt gaatataagg
    61201 gagaagacaa aaatcatatg agagttgttg ggagaatatc aaaaaccaac ataactaagc
    61261 tattcttaga aatagttgac aattaaggag gtatgctggt gaaaaaccta attatatatg
    61321 cagtatcaga ttcagtaggg gagactgcac aacaagttgc aaaggcatgt atgtctcagt
    61381 tttatgtgaa tgaaacttat gaaataaaaa gatttccata catgattaat aaaggagtac
    61441 tacttgaaac tttggagaat gcaaaagctg aaaacgcttt aattgtatat acattagttg
    61501 atgaagaatt atgcagtatt gttgaaagat attgcgaaag agaaggtctt agttgtatag
    61561 atttaatgac agatatacta agagaaataa gcaagagaac aggaagaaaa cctaaaagag
    61621 aagctggtat aattagaaaa ttagatgaat cttactttaa gagagttgaa gctatagaat
    61681 ttgcagtgaa atatgatgat ggaaaagacc ctagaggtgt tcttcaagca gacataattt
    61741 tagtgggaat atcaagaaca tctaaaactc ctttgagtat gtatttagct aataaaaata
    61801 taaaagtagc taatgttcca ttagttccag aaataccaat tcctaaagaa gtgtttgaga
    61861 tagatactaa aaagataata ggtcttacta attcacctga aaagctgaat gagataagaa
    61921 cccaaagatt aaaagcttta ggattgtcca gtaaagcaaa ctatgctaat ttagaaagaa
    61981 tacttcagga gttagattat tcagaagaga taatgaaaag aattggatgc ccagtaataa
    62041 acgtttcaaa taaggcaata gaagaaacag caggtataat tttagacata atgaaagaaa
    62101 atggtctaaa gatatacaaa gaaatagaaa tttaataatg tctattaata aaaatgatat
    62161 aaattaaaat aaaaagatta atgggggatt taacaatgga aactaagtat gtttatagtt
    62221 ttggtgaagg aagcaaagac atgaaatctt tactaggagg taaaggtgcc aatttagcag
    62281 aaatgactaa gataggctta cctgtccctc ctggattcac tataacaaca gaagcatgta
    62341 atgattatta tgttaacaat gaaagtataa gagcagagat aataaaagaa atagaagagc
    62401 atttagctac tttagaaaaa gacttaaata aaacattagg atgcaataag aatccattat
    62461 tagtatcagt tcgttctggt gcagtattct ctatgccagg aatgatggat acaattctta
    62521 acctaggtct taatgacaat agtgttgttg gcttagcaga ggctacacaa aatgaaagat
    62581 ttgcatatga tagttacaga agattcatac aaatgttttc tgatgttgct atggaagttc
    62641 caaaatataa atttgaaaat gtattagaca gagtaaaaga agcaaaggga tacacagttg
    62701 atacagaact tacaactgat gatttaaaag aaatagtaaa agaatttaaa gcaatttata
    62761 aaaaagaaat aaaaaatgat ttcccacaag acccaaaaga gcaattaatg cttgcaatag
    62821 aggctgtatt tagatcatgg aataatcctc gtgcaatcgt ataccgtaaa ttgaatgata
    62881 tagctcataa cttaggaaca gcagtaaata ttcaatcaat ggtatttggt aatatgggag
    62941 aaactagtgg tacaggtgtt gcatttacta gaaatccagc tacaggagaa aataaattat
    63001 ttggtgaatt tttaatgaat gcacaaggtg aagacgttgt tgcaggtata agaactcctc
    63061 aaaatatatc aactcttgca gatgtaatgc cagctgtatt cgatgaattt gtaaaaatta
    63121 ctcatatact tgaaggtcat tataaagata tgcaagatat agagtttact atagaaaatg
    63181 aaagattata tatactacaa actagaaatg gtaagagaac agcagcagca gcaataaatg
    63241 tagcggttga tttagttgaa gctggaataa ttgatgaaaa agaagctatc atgagaattg
    63301 agcctaatca attagaccaa ttattacatc caaaatttga agataaggca ttaaaagaag
    63361 ctaaggttat agcaaaaggt ttaccagcat caccaggtgc agcaagtggt aaagtttatt
    63421 tcaatgctga tgatgtagta aaagcaaatg aaaaaggaga aaaagtagtt ttagttagac
    63481 tagagacatc tccagaagat atagaaggaa tggttaaagc agaaggaatc cttacagcta
    63541 gaggtggaat gacatcacat gcagcagttg ttgctagagg tatgggtaaa tgttgtgttg
    63601 ctggatgtgg agaaataaaa gttgatgagt ttaataaaga aataagagca cttgatgatg
    63661 tagttataaa agaaggagaa tacatttcta tagatggttc tacaggaaat gtatacctag
    63721 gagatgttaa gaaaacagaa gtatctttaa ctggaaattt tgaaaaatta atgaactggg
    63781 tagacaaaca caaatgtatg atggttagaa ctaatgcaga taatcctaga gatgctcgtg
    63841 cagctataga gtttggtgca gaaggtatag gtctatgtag aactgagcat atgttctttg
    63901 atgaagctag attgccagca gttagagaaa tgatattatc taatacagta gaacaaagag
    63961 aaaaagctct tgaaaaaata ttaccaatgc aaagagaaga ttttgtagag ttatttaaag
    64021 ttatggatgg aaaaccagtt aatataagat tactagaccc accactacat gaatttttgc
    64081 ctcatgatga tgagactata gaagaacttt caaaatctat gggaataaaa gtaagtgata
    64141 ttaagaagag aatagttgat ttagatgagt ttaacccaat gcttggacac agaggttgta
    64201 gacttgcaat aacttatcct gaaatatgtg taatgcaatc taaagctata atacaaggtg
    64261 ctatagaagc aatcaaagca ggtgttaaag tttctccaga gataatggtt ccattagttg
    64321 gagaagtaaa tgagttaaaa ataataagaa aaatgatagt agaaactgtt gacgctataa
    64381 taaaagaaga aggtatagaa gttccttata ctgtaggtac tatgatagaa atacctagag
    64441 cttgtttaac tgctgatgaa atagcacaag aagcagactt cttcagtttt ggtactaatg
    64501 acttaactca aatggcattt ggatattcaa gagatgatgc tggtaaattc ttaggtcaat
    64561 atgtagatga agaaatatta gaaaaagacc cattccaagt actagaccaa aatggtgttg
    64621 gtaagttagt taagatggga gctaaattag gtagagaagt taaaccagaa ttaaaactag
    64681 gaatatgtgg agagcatgga ggagaaccat cttcagtaga gttctgttat agtgtaggac
    64741 ttaactatgt atcttgttca ccatttagag tgccaattgc tagacttgca gcagctcaag
    64801 catctataaa aaatcctaga taataataga ctgcaaaata tgtaactaaa taaaaataaa
    64861 atcccctatt gttcaatgta tcaaattaag tatttgtaaa ttgaatatag gggattttta
    64921 ttataaaaat ttaacttata tagttgtaag tgaaacgtat ttaattatat tgcatatatt
    64981 attgtagaga gaaatttcaa ctatcaatta aattgagttt actggagggg ataaagttga
    65041 caaagtgtcc taaatgtgga aaggaagtat catcacgtcc aggtagtata tgcccacgat
    65101 gtggatttaa agtagcagat gagagtctaa aaataagatg tccagaacct agttgtaggg
    65161 ctttggtatc taggaaattg gattattgtc ctaaatgtgg atgcaaactt agaggatata
    65221 atatttctga atttgttaac atggtgagat gtaaaataga tgagacattt gataaaaaat
    65281 aattaaattt agagttaagc ttttgagggt gtctcaaaat gaacttttta gttcataagg
    65341 cactcttttt gtatggaatt aaatatattt ttataattta aacaataaaa aagaggctta
    65401 tctctatttt gagatagcct ctataaaatt atacagtttt ataagcaaat atatttttac
    65461 taatctattt ctattatttg ccttctgaat cttccatgac taaagccacg agtgtgcata
    65521 actatttttt aatcaaacgt atgttaaagt aatctttcta tttaccagaa ttattttcca
    65581 gtattaagta tccaaggttt ttctatacca ttttttagtg agttataatt cacaataaga
    65641 gtgtcatagc tatttttagc atcttcatta cttaccactt gttttttata atcagttaga
    65701 gtaattaatc ctaaatcata tcttaattta gtatttttta attgtttttc tgataaatca
    65761 agttgttttt tagtaatctg aattgtatct tctaaagcaa gtaattgagc atagctatca
    65821 attaaccctt ttttaagagc ttttttactg tcttctaatg ttactagacc attttcggta
    65881 ttaaattttt gttgaagata atttgcataa gtagtaaggc cagcagcata agtctgtctt
    65941 tcaagattgt atgcttcaac ttctttttca tatctcttgt agtctttttc atacttatcc
    66001 gtaagaacct tatattcatc atcagttagg ttaccttgct ctggttttgt aggagcaact
    66061 ggtcttgtaa gattaggtct atctggtaaa tctgctttgt tctcatcttt atcattaaag
    66121 ctttcttctg tacgttctaa aatcaattgg tcgtatttta aatattcatt aaccttacct
    66181 tccatatatg aatcaactga gccacctact ctaaaagatt caaatctata ttctttatcc
    66241 aattgataat tatttaaatc tatattagtc aacaacttaa agtagtcttg attgtttttt
    66301 agttcttgaa gtttagcttt ttgagtattt tgtagtgttt gaagttcaag ttcagctgat
    66361 tcagtttcta aagatgttac taaccctaaa tcttttttta atttcatatc tttaatttct
    66421 ttagttttta tttcaagatt gttttttatc ttgtctagct cattttctct tgaaactaaa
    66481 tcgttaaatt tattagtaat atcatttgct atttggtcct ccataaagcc tttagcctgt
    66541 tcactttgat ttttaagaag tccaatttgg tcgtatggaa acgagttgtc acttccagta
    66601 aaactatcaa actcatcttg tacttctaac ttttctttta acatttttat ttcttctgat
    66661 ttcattttta atttttcact atttttaagt gcagcactaa cagcttctct agcagtcaaa
    66721 atttcctttt cagatgttct tttatttgag tcacttaaaa tagaattatc aactttgttt
    66781 atagaagaag tattattatc tgcgtaaact gggattaaat tggcagttat tataccaaca
    66841 ccacagccaa ttgcaactat tttgctcatt tttttattca atacaatcac cctccattct
    66901 atttaaactt tagctttcaa ttttggtttc tttattattt tacgttttat acttcctatt
    66961 ttatctgtta tcttaccaaa tattttaggc attttgtctg aaaacttatt ttcccattta
    67021 tcaaatatta agtatatagt aggtataagc accaaagtta taagtgtaga tacagttaga
    67081 ccacccatta taactatggc tagtggttgc atagtttctc caccttcacc aagagatagt
    67141 gctgttggca acatacctaa aattgttgtt gctgtagtca ttaagactgg tcttaatctt
    67201 gctgcacaac caattgaaac caaaccaatt aaatcattgt tacgatttgt ttttctaagt
    67261 tgctctatgt agtcaataag aactatacca ttattaacaa caataccgat aagtaagatt
    67321 atacctagca taccgacagt acttaaactt tgaccactaa ctagaagcga aagcacaact
    67381 ccaacgaatg caaatggaac acagaacatg attataaatg gtttactaaa tgattcaaac
    67441 tgagctacca ttaccatata aactaatgct atagctatga ccattgaaaa tccaagactt
    67501 gccatagatt cattcatcat ttctgtttca ccaccaacac ctatagagta atctttagga
    67561 attaccattt tattcgtttt ttctagtgct agttttgtag cagtaccagc atctaaattg
    67621 tcaagtgtag cagttatatt tacagaaaaa tctccatcag tcctagatat agattgtaga
    67681 ccatctgcca tttttatatc tgaaaaagca ccaagaggaa cttcttttcc agttgcagag
    67741 tttactttta gttgctttat atcttctaag ctatcaatag tatctgcttt aaattttagg
    67801 tttacatcca ctttgtaatc atcaatagta gcagtggtta cggagtcacc atttattgct
    67861 gtacgtaaca tgcctgcaat ttcagcggta tttacaccat attcttgagc cttatgttta
    67921 tctatagtaa attgagcttc ttgtgttgta tctgtaagag aagtttcaac atttctaaat
    67981 ccttttatag agctaaattc tttttcagct tcttttccca gtatttttaa tacatctaaa
    68041 tcaggacctt tcatttctaa tgtgaagtct gctcctccag ctccacccat aacactactg
    68101 ttttgactta catttatttt acaatctggt acagtagcca ctctatcaat tatctctttt
    68161 tctatttcat cagtagttct ttttctattt ttttgagatt ctaattcaat tgctatactt
    68221 gctttactat tatttgaatc tgatgtcaaa gttgttatta aagttttaat ttctggaata
    68281 tctgagactt ttttctcagt catagataca tagtaatcat tggattctag gctaagacct
    68341 tttggaagtt ctatagaaat agataattca cccttgtctg ctgcaggcat aaagtccata
    68401 cctataaatc ccattccaaa taaggaagct acaaaaataa gtaaacttga tattacaact
    68461 aagcgttgat gtctcaaaca tacacttaat aattttttat atgcttcact taccttatca
    68521 aatataggac tatctttttc ttgcatcttt tgactatttt ttcctctgct taattttgca
    68581 aatacactag gaacgagtgt aattgcacct ataaaggaga atgctagtga agctattagt
    68641 gttttaccta atgccccaaa agttatttta gctatacctt ctgtaaacat gataggtaag
    68701 aatattgcta ttgtggtcaa tgttgatgca agtattgcat ttgttacagt tcttgttccc
    68761 tcaatagcac aatcatcaag actcaatctg ccacttttcc tatatttaaa tatattttca
    68821 attacaactg tagcattatc aacaaccata ccaactgaaa ttaccaatga acttgcagta
    68881 ataagattta aactttcacc agtaaagtag agaattgcta tagcacctat tatagaaatt
    68941 ggtattgcaa ctgcaacaac tagtgaagct cttacacttt ttaggaaagc aaatattaca
    69001 ataaatgcga taacagcact tataagcaag ttgctcatta cactgtttat tgattcactt
    69061 atgtatgaac ttgtatcatt agcaatttta attttaaatt gaggattttc cttattcaat
    69121 tcatctacgt atttgtatgc actctgcata acttttacag tgttggcatc ttgttgttta
    69181 gaaatatcta ttaccaaact gtcttttcca ttgtatctat aaatactatc tttgtctgca
    69241 tatccataat ctacactaca aagattatct aatctaactg tatttcctcc ttttacagga
    69301 atttgaatct gttttatatc atctagggat tctaatttat caatcgctct taaaactatt
    69361 ttatcctcac cttgagtaat tgaaccataa gggaatgttt tattactaga ggataagaca
    69421 ccttttatag tggataaact aaccccataa tttgaaagaa cagctgggtc agctattaca
    69481 ttaacctgtg ctttttttcc acctttaagg tctgctgaag taacaccatc tatggattct
    69541 attttaggct gaattacatc ttcagcgtat tttcttaagg cttgtgaact attttcattt
    69601 cctccagata tgacaagttg acctatggcc tgtgcattca tatccagctt taaaactgtt
    69661 ggtttagctg catcatctgg gaggctggtc tgtaatgcat caactttaga cctaacatca
    69721 ttcattattt catccaaatt agttccaaat tcaaactgag caactaccat agaaacactt
    69781 tcttgtgaac ttgatatagt agattttaca tttgaaacgg cagataaact ttcatcaact
    69841 ttttgactaa cttgttcatc aacgtcttga ggaccagcac ctgtccaagt agtcatgacc
    69901 attacaactg gtatttctat atcaggcatt agatttattg acattttttt atatccaata
    69961 ccaccaaaaa ctattaatac taaaaagacc attatgattg tgagaggacg tttaacggaa
    70021 gtctgtgtta aattcatagt ctacttctcc ttttctacag gaaatatctt agttccgtca
    70081 gaaataagac ttatccctcc aataatcact gtatctttat cacttacacc acttttaatt
    70141 tctattttat cctctgttac aattccagtt tgaaccaagt gtttctttgc tatattgtct
    70201 tttgttgcta tgtatacata ttttttacca ttttcttcaa atattgcttt tttaggtact
    70261 gtaacagcac cattttcttt ttcaacactt aagtttactt gagcagacat acctgcctta
    70321 aatttgttgt ttgtattatt tacaagtact ttaacaggat ataaagatgt ctgagggtca
    70381 actactgaag gtacataatc tatttttcct aaaatccttt ggtcttcaat tataacatct
    70441 acatttccat ctttcttaaa tttacctata tctgattctg ctacatttaa atcaacttct
    70501 agtatactag gattagaaat aataaaagct ggttgtgatt gtgttatcat ttcctttgaa
    70561 tcaaagtttt tagctgttat tgtaccatct actggagatg ttaatgttaa tttgtctaaa
    70621 ttactcattg ctaaattata tgatacttga gcttggtcaa gctgtttttt agcaagtgct
    70681 ttagcttgag gtatactttt tgaagttgct gtatcgtatg ctctttgagc agaatctaac
    70741 tgttgttttg tttgctctaa agaaaattct atttttttaa attggtctaa actaatgact
    70801 tcctgttcat aaagaatctt attattgtca taatttcttt gagactcctc atattgaatc
    70861 tttgcattgt caagagctgt ttttgcctga tttacttgtg cctctaatga accaccagtg
    70921 gcacttgaat aacttgcttt tgctaaatct agtgaggctt tactttgctt tacactattt
    70981 tctagctctg gactgcttat actcaataat tcatctcctt ttcttacatt ttgcccaagt
    71041 tttacataca cttcttgaac tgtgccaaca gtctgtgcag taacagctgt ttcatcttta
    71101 acctttgtag ttcctgagaa agaatttgtg ttttcaattt ctccacctat tgctttttga
    71161 acagaaactg ctattggttt ctcaggttca gattcttctg tttttccaca tccaactaaa
    71221 aacagtgaac tacacattaa gaaaactatt aaatatcttt tcatatctcc tcctattata
    71281 tattgcacac tagcttgttg tagaatttaa agtgtcttat aatttaagtt tagttttaga
    71341 ctaattaaaa aacttccctt tattggcaat ttataattct ctaatttgat tataaattta
    71401 taattattat gagtcaataa ctttttcttg ttttaaattt attaatagtt tataatttat
    71461 actatattaa acaacaatgt tttattatat tatctattga agggatgtta caaatatgga
    71521 taacaacaat atacttaaaa tagcggactc ttttttagat tttttatttg tgcttgaaaa
    71581 taatatattt aaagaaagcg atttgttaaa aaagtttcaa aataactctg atataatgaa
    71641 agcttatttt gaagaatgtc caatggctcc atcacatgct aaggtaattc tttatcttat
    71701 gacatcaaat tcatcatcaa tttctcaaat agcttctaat ttaggaattt taaaatcaaa
    71761 tatgactccg attattgaca gattagtgga acatggttta gtcaataaat ttcctgaccc
    71821 aaaagataga aggattctta gggttgaatt aacagataaa gcatttaaat tatttgatgc
    71881 agtaaaagct attctcaaag aatctctagt aaaaaaatta tctaatcttt ctgaagagga
    71941 actaacttta ttagatgaac atacattaaa gttatcagaa atagtaaaga aattaggtta
    72001 gagtgtgatt gtaaaagtca ctattaaaaa agttaaaact tcataagaaa agaaatagca
    72061 gtaatataat atagattatt atactactgc tatttctttt cttatgaata tttagttgtc
    72121 aaactctatt ttccaattga aatagccagt atctggattt ttatcatatt ttaatgtagc
    72181 atcaaattta ttaccgtttt tagcagttaa agattttact ttagtttcac ctttttttaa
    72241 aatatttttg accattgttt tgttaacttt ctttttataa agacttaaat acttatcatt
    72301 tttccaaata acaaatttac attctttatg atttttacaa gcaaagcctt tgtcaaattc
    72361 tagtacatca ccttgacaaa tggggcattt gccaagagat tgattttcat caccattttt
    72421 aacttctttt ttgttattag aatcctttga tatagcaact tctttttcag tattagttac
    72481 atcttttttc tgtttttttt cttttgtttt agtaaatttt ttagtttttg aatcgaaagt
    72541 atatgcttct gtgtttatat tttttgaagc atcttgtttt ataatattga cattttgata
    72601 tataaaacta atgatattag taagatattc ttttcttgta tactttcctt tttgaatatc
    72661 gcttaaactt ttttcaagtt ttccagtata atctacatca aataagtctt taacaggaaa
    72721 aatttcaact aaatttttcc caaggtctgt tatagaataa gatttacctt ttttctttac
    72781 atagcccact tgacttatct tctttaacac atcagcacgt gtggctgatg ttccaatcga
    72841 atatccagat agcactgttg tatcttcttc aggcacattt ttaccacaat ttttcatagc
    72901 ctttaaaagt gtgtcctcag tatatggttt aggtggagta gtttgcttag ttaatggttt
    72961 tatttctaac acatctacaa catcatcttt atttacaagt ggaagtaaat cgtttttttc
    73021 ttccttatta tatacctcaa ggtatccttt tgatttaagc accttacctt ttgttaagaa
    73081 agtacaatta tctacttcag tcttaatttc tgtattctca tattcagcag gaggcataaa
    73141 gtttgctaca aatctatctt ttatggcatc ataaactaat tgttcatcct tagataaact
    73201 ttttggaatt atataagttg gaattatagc actatgggag tctactttag aagaatcaaa
    73261 aactctttta gttttagaaa atttaatttt attttcatat tcaagaccaa cctttaattt
    73321 atctaaagtt tgagaagctt ttgaagccaa actttcttct aagaaaatgg aatcagttct
    73381 agggtaagtt atgtatccac ccttaccatt accctcatag agagattgac agacatttaa
    73441 aaccttatca gatgtaaaat tggaatactt agaagttata tatccttgaa gtgatgtcaa
    73501 actaaaaagt tttggtgcat attcctttga catagtaact tttttatcta gtattttacc
    73561 agtttcagat gtaattgaag ctataatttt atttgcatct tcaagtgtat caaatttact
    73621 ttctttaccc ttaacatatt tacctttata ttcaccagct tcagctttaa aatgcccttc
    73681 tatttcataa taggttttag gaacaaagtt tagtatttcc atatctctat catagactaa
    73741 tttaactgtt ggaagaatta ccctacctat gtttaatagt ttcccatttc catatttcaa
    73801 tgtagcaaca gaagtgaaat ttattccaat caaccagtca gtaataagcc tagtatatcc
    73861 agcagcttga agatttctca tttcatcttc atcttttagg ttttttatac ctcttgtaat
    73921 atcttctggt gtccattcat ttaccaagat tctttttact ggttttttat tttttgccag
    73981 taaaaatatt aaaaatgcta taagttctcc ttctcggtca ttgtcagtgg catttattac
    74041 atattctaca tcttttctat tcaaaagctt ttttacagtg ttgaattgtt tagttttaga
    74101 actatcaatc ttaaatttaa acttatcctc aggaacaaat gggaaattgt tcattttcca
    74161 agagccagag tatttatctt tatcataatc cttcatatca tataatgata ctaagtgtcc
    74221 aactgcataa gtaattatat aatcatttcc ttcaaagtaa ccatcttgtc tggtctttgc
    74281 acctaaaaat gatgctatag tttttgccac agatggtttc tcagcaagta caagtttcat
    74341 aaaaaatcct cctttaaaac actaataatt atattaccac aaaaaaataa aaaacttcaa
    74401 gaggtcgaaa tttaagttat aatatttata gaaagttgaa aggagatata agatgtacaa
    74461 tttaaaagta aaaaaattaa atgatgatgc tataatacct aattttgctc acaaaggtga
    74521 tgctggtatg gatttgtatt ctatagaaga ggttgtaata cctcctggag agactaaact
    74581 tatcaaaact gggatatgta tagagcttcc tactatgaca gaagcgcagg taagacctag
    74641 aagtgggctt gccttaaagc attctgttac tgtattaaat acaccaggaa ctattgacga
    74701 aggatacaga ggagagctta aaattatatt aataaatcat ggtaaaaatg attttaaggt
    74761 tgaaaagcat atgaaaattg ctcaaatgat agtaaaacct atctatgata ttaacataga
    74821 agaagtaaaa gaattaagtg actccgaaag aggaaaaggt gggtttggct caactggatt
    74881 ttaaaaagtt acaaaaaagt taaaaaatat agccattttt aaaaaaggta aaagatggct
    74941 atattactaa attacaggct attaaagatt aaaatttata catggtaatt tatggtaagc
    75001 aaatattact atagacaaat agttacaaat ttgtaataat attaatataa aagaaataat
    75061 tgatatttta atagtgtcaa ttatttcttt tatattttga agtgaaataa agatagtaga
    75121 aaagaggaga tgagtggaaa gttatgaatt ttaatcaaaa gagaatagca gccagtataa
    75181 tggcaactgc gataataatg cctactatgg ggaatttagc atatgctaat gagtctgaag
    75241 tagagagtgt gagtatagaa agcagaacaa taacagggaa tgcggtaaat tttagaaaag
    75301 gaccaggtac aaaccatgaa tcaatgggga aactttacaa aggtgataaa gttgagtacg
    75361 taggaaaaga aggttcttgg gtaaaagtta aatataatgg aaacacaggt tatgtgcatg
    75421 gaaattatgt agcaataaat agccttggaa gtagcaatga aagtagtgat acttcagtta
    75481 agtcgacaaa agttgtaaca gcaaaaggat taaattttag aacaggacca agtacaagta
    75541 gttctaaaat atcaacacta ggatatggga ctgaagtcgg atacatatct gagtcaaatg
    75601 gatggtcaaa aataagttct aatggtagag taggttatgt ttcaagtaaa tatttaggaa
    75661 ctagtgtaaa tgactctaca aatgaaaatg ctgaaaacag ttcaaatgac cttgtaaagg
    75721 gtacaaaggt tgtaacagca aagtcattga acgttagaac aggaccaggt acaagtcatt
    75781 ctaaaatagc tacattaagt tatggtactg aggttggaag tatttctgaa agtggaggat
    75841 ggacaaaagt aagttatggc aatcaaactg gatatgtgtc aagtcaatac cttgctgaaa
    75901 aaggttctgt tgatacttca attccatctt attcgactaa ttctccaagt caaggagctg
    75961 atagtgtaat aagttttgca aagacactac ttggaaaacc atatgtatgg ggagcagaag
    76021 gtccaaatag ttttgactgt tctggattca cacagtacgt tatgaaaaaa tctgtaggag
    76081 ttagtatacc aagagtatct agagaccaaa gtaagtatgg aacatatgta aatagaggag
    76141 accttagaag tggagattta gtattctttg atacacaagg ttcaaataat ggttctgtaa
    76201 gtcatgttgg aatatacata ggaaatggag atatgataca tgcatcttca ggttcatcaa
    76261 aaaaagtaac aatatctaat ataaatagta gctactattc aagtagatat gtaaatgcaa
    76321 gaagagtttt ataattgttt ttattataaa acctaataaa tagatttttc tttattgctt
    76381 ataatatgaa agcaggtaca atattgatag taatgtatag tataatacat gttactattt
    76441 gattgatacc tgctttttat ttattttctc tgtttataga aaataaatta tatttatatt
    76501 ttttataaat tttaacacaa cagtaaatta taaattatca aataataata gttatacaaa
    76561 taaaaatttt agaacatttt ttgagattct tctaactcgt aagcatccat taaagcttca
    76621 ccaaatcttt gatagtgaat tatttctctt tgacccaaga attttaatac atctataaca
    76681 tcaacgtcat ctgttaggtt tataagttga taataagttg caagtgcttt ttgttcagct
    76741 gccatatcct catgtaaatc ggttacggga tttgacataa ctgctatagg tcttacatca
    76801 aatggaacac catttgaatc tgttggataa attccatatc cattttgagc atagtttgaa
    76861 ccaagacctg cagcttttaa ctcttctggg cttgcatcag aagttaactg ataaaccata
    76921 gtacatataa gctcaacgtg agctagttct tctgtaccaa tatctgttaa aagtgcacgc
    76981 atattaccag taggcattgt atatctttgg cttaaatatc ttaaagatgc agcaagttct
    77041 ccatttggcc caccaaattg agttataaga aatttagcca ttctagggtc acaagttttt
    77101 atattaactg ggtgttgtat agttttctga tatatccaca tgaattttca atcctccaat
    77161 acttgatgtc taataattaa attctctgtc ccaaggccaa ggttggtcag cccattgcca
    77221 agggcatcta cttggagcat acccaaagtt agttaaagga ccgtatttat tttcgtaagc
    77281 atatctagct tgcgcaaatt gattacataa tgaattataa gtgttgatag catttttatc
    77341 atcagggtga ttgtctaaat ataagttcat atcaacacat gcaaaagatg tttcctgaac
    77401 ttttctcata agttcagctc tagatgagtc tttcattatc ttctacctcc tctatatttt
    77461 tttggcttag catataattc tttgttgtac atttcagact ctagtaagtt tagttctgga
    77521 aatatagttc caaattttaa tgcatcagaa aggcagtaca tttctgtgaa aatttgatta
    77581 ttaatgtatg gtctagccaa agatggacca caattttttt tgatatctct agtcttattt
    77641 tccaagatga aaacctcctt gttgtaaata gataggtaac tctatctagt gtataatatt
    77701 caatcattta aaaatcgtta ctaataataa aatattaaat gagaaaaata aaaaagataa
    77761 taaaagaaag aggttattta tgttattata agtttatgtg ttattgtaaa ctataaatta
    77821 tttagtaaaa ttaaagtaaa aattatagta ttttgtggat gaaggtagac ttttttgtaa
    77881 aatattatta acataaatat acgaggtgat tagatgagtg aactatcagg aaaaggctgt
    77941 gaaattatag ttccttttga ggaaagactt ccagtaagag atatagaaaa aagtataata
    78001 aaaaaatata gaaaaaattt atggtctaag tttatgaagg caataagaga ttataaattg
    78061 gttgaagaag gtgataagat agctgtagcg atttctggtg gaaaagacag tattcttatg
    78121 gctaaaatgt ttcaagagtt aaaaaaacat ggacaagtta attttgatgt tgaatttatt
    78181 gctatggacc ctggatatca tgcaaatata agacaattac ttatagataa ttgtgagtat
    78241 ctaaatatac caatacattt atttgattca aggatatttg agatagcaga tgaaatagca
    78301 aaagattatc catgctatat gtgtgcaaga atgaggagag gagcattata ttcaaaggca
    78361 gaagaactag ggtgcaacaa acttgcatta ggtcatcatt atgacgatgt aatagagaca
    78421 acaatgctta acttattgtg tgctggaaat tttaaaacaa tgcttcctaa acttaattct
    78481 actaattttg aaggtataaa aattataaga ccactttatt atataagaga agaacatatt
    78541 ataagattta ttcaaaatag tggtatatgg ccattaaatt gtgcatgtat ggttgctgct
    78601 aaaaaaacag gtaataaaag atatgagata aaagacttaa taaagagttt agaatcaaat
    78661 tttaaaaatg tagaaaaatc tatatttaag gcggcagaaa atgtaaatct tgattcagta
    78721 cttggttggc aaaaagatgg ggagaaacat tctttcttag aaaattttga ataaaaatag
    78781 ttaaaaagaa tcactataaa caattggaaa gggtgtttat attgaaaaga gtatatatag
    78841 attttgaaat gaatatgcca aattctaaat caaaaagagc agtatttaat tctgatataa
    78901 ttgcaattgg agcagttgtg tatgatgaaa aaacaaaaaa tattgataaa tttaaatctt
    78961 taataagacc agtaagtaat gaggagttgt atcctcatat acaagaatta acacatatat
    79021 cttctgaaga attgaagagt gcaccaagtt atgaagaggt catgagaaag tttaaaaaat
    79081 ggcttggcat attttctgat attaaaggaa tatatacttt tggtaatttg gatttgacat
    79141 gtttcaataa cacagatatg agaagtgcta aaaaaaataa ccatccaagg tttgtaaata
    79201 acattagaga tttatttgta gatataaaag aaaaatatat aaattgtggt atgagatgta
    79261 tgaactatat atcattgaaa aatttacttg aatttgttaa cttagagttt agtggagatg
    79321 cccatgaccc attaaatgat gcatataatt tatttatttt ggatgaggca atcacaaata
    79381 atgtagatat acaaaatctt ttaataatac gtgacataat aagaccacca tttaacgata
    79441 taaattctaa tttagataat tgttttaaca aatttaagga gtcattatat aaaaaagaag
    79501 gaaattataa tattgtagat ttttctgttg aaataataaa aactgtgaga atgtacttat
    79561 taacaatcat agatgtaaat atacaaaatt tagaaattat gaaagatata agtaaaaaaa
    79621 tggatactat agataaattg aaagatatag aggaaggcta tttttattta ttagaagatg
    79681 tgtacttcga catgaaagat gtactagaag atttaatgct ttatagaatg aatgaagatg
    79741 agtacaagta tgagataaaa aatataataa aaatgtttga tgaagactta gataatgaaa
    79801 aaatatatat aaataaatgt aataacctaa atgttgttaa taagatataa gaaattataa
    79861 ataatagagt agaacttgac aattataaca attttttata aaactgaatc aagataaaat
    79921 taaattaata taaaaataat atacaataaa aaatgtagag agatacttac tttctacatt
    79981 tttttattgt atattgcttt aggtttaaaa atatattata tactttataa tcaatatatt
    80041 ttatctatat tttacactta taaaatatga aaactactta ttgcgaaagt aattgatttg
    80101 ttgtattata atttacatga attatgtagg acaatcaaaa gtcagtatta taagagtaca
    80161 tatattcaaa tttttaacaa ttaatttata taattaaaaa atgaagggta ggatgaagtc
    80221 atgggtttta gagaagtaaa aattgaggaa ttacagttta atccatttac taagattggc
    80281 aaagaatggt tacttataac agctggtgat tcagaaaagt ttaacacaat gactgctagc
    80341 tggggtggtg ttggagtcta ttggggtaaa aatgttgtta caacttacat aagaccacag
    80401 agatatacaa aagaatttgt agatagtaat gatacattta cagttgcctt ctttgatgaa
    80461 acgtatagag aggctttaaa tatttgtggt actatttctg gtagagatat aaataaaata
    80521 gaaaaagcag gacttacacc atattttgtg gatgatacag tagcttttga agaagctaat
    80581 atgattatag tatgtaaaaa gctatatcat ggtaatatgc caccagaaaa ctttgatgct
    80641 aaagaaaatg ataaaaaatg gtatccagag aaagactacc atactatgta catttcagaa
    80701 attataaaag ttcttgtaaa agaataatta taataaaaaa tatatgaaaa gaacttatta
    80761 taagtaaatg actgtgcttt cttatctgat atctaagtag atgctagtaa ctaaataaat
    80821 attaatttta aataaatact attataaaaa agatgaacta tatttactat agttcatctt
    80881 tttatttata taagcactta tataagtaga gatttatttg aataaaagta tttatttgaa
    80941 atatttgagt atactttata agtattttta tgctaactag aaacacttaa tttatggcat
    81001 ttgtatttga tttattttaa tgtaaataat ttcaaagt
//
LOCUS       DAYAKB010000010        75768 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.010, whole genome shotgun sequence.
ACCESSION   DAYAKB010000010 DAYAKB010000000
VERSION     DAYAKB010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75768
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.010"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            440..1234
                     /locus_tag="ACGI3L_000814"
     CDS             440..1234
                     /locus_tag="ACGI3L_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HFG9196541.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            1258..1701
                     /locus_tag="ACGI3L_000815"
     CDS             1258..1701
                     /locus_tag="ACGI3L_000815"
                     /inference="COORDINATES: protein motif:HMM:NF025547.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HFG9196542.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(1790..3076)
                     /locus_tag="ACGI3L_000816"
     CDS             complement(1790..3076)
                     /locus_tag="ACGI3L_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFG9196543.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(3294..4184)
                     /locus_tag="ACGI3L_000817"
     CDS             complement(3294..4184)
                     /locus_tag="ACGI3L_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9196544.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEIIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            4476..4820
                     /locus_tag="ACGI3L_000818"
     CDS             4476..4820
                     /locus_tag="ACGI3L_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFG9196545.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(4979..7075)
                     /locus_tag="ACGI3L_000819"
     CDS             complement(4979..7075)
                     /locus_tag="ACGI3L_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HFG9196546.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNGLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(7088..8248)
                     /locus_tag="ACGI3L_000820"
     CDS             complement(7088..8248)
                     /locus_tag="ACGI3L_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFG9196547.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVATILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(8267..9334)
                     /locus_tag="ACGI3L_000821"
     CDS             complement(8267..9334)
                     /locus_tag="ACGI3L_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HFG9196548.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            9686..10252
                     /locus_tag="ACGI3L_000822"
     CDS             9686..10252
                     /locus_tag="ACGI3L_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9196549.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(10466..11452)
                     /locus_tag="ACGI3L_000823"
     CDS             complement(10466..11452)
                     /locus_tag="ACGI3L_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HFG9196550.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGTRAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISEGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(11482..12177)
                     /gene="pxpB"
                     /locus_tag="ACGI3L_000824"
     CDS             complement(11482..12177)
                     /gene="pxpB"
                     /locus_tag="ACGI3L_000824"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HFG9196551.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(12197..13417)
                     /locus_tag="ACGI3L_000825"
     CDS             complement(12197..13417)
                     /locus_tag="ACGI3L_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFG9196552.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(13446..14237)
                     /gene="pxpA"
                     /locus_tag="ACGI3L_000826"
     CDS             complement(13446..14237)
                     /gene="pxpA"
                     /locus_tag="ACGI3L_000826"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HFG9196553.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            14825..15454
                     /locus_tag="ACGI3L_000827"
     CDS             14825..15454
                     /locus_tag="ACGI3L_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HFG9196554.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(15568..17082)
                     /gene="glpK"
                     /locus_tag="ACGI3L_000828"
     CDS             complement(15568..17082)
                     /gene="glpK"
                     /locus_tag="ACGI3L_000828"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFG9196555.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            17326..17868
                     /locus_tag="ACGI3L_000829"
     CDS             17326..17868
                     /locus_tag="ACGI3L_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9196556.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            17873..20374
                     /locus_tag="ACGI3L_000830"
     CDS             17873..20374
                     /locus_tag="ACGI3L_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9196557.1"
                     /translation="MFTLNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPAR
                     TIIQNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLI
                     CGLSSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIA
                     NILGSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGT
                     LMLICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILS
                     FEYFLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIA
                     APLSGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFT
                     MGTPLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDL
                     VGKPSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKS
                     LLNKVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGE
                     NKLNSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKE
                     LTTAYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVN
                     EQKESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRTMESQKKELQSKLNNSISQ
                     KKDMEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTL
                     QSTLNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            20795..21193
                     /locus_tag="ACGI3L_000831"
     CDS             20795..21193
                     /locus_tag="ACGI3L_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9196558.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(21410..21619)
                     /locus_tag="ACGI3L_000832"
     CDS             complement(21410..21619)
                     /locus_tag="ACGI3L_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196559.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(21651..21860)
                     /locus_tag="ACGI3L_000833"
     CDS             complement(21651..21860)
                     /locus_tag="ACGI3L_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFG9196560.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            22159..22578
                     /locus_tag="ACGI3L_000834"
     CDS             22159..22578
                     /locus_tag="ACGI3L_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196561.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            22806..23261
                     /locus_tag="ACGI3L_000835"
     CDS             22806..23261
                     /locus_tag="ACGI3L_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196562.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(23482..23742)
                     /locus_tag="ACGI3L_000836"
     CDS             complement(23482..23742)
                     /locus_tag="ACGI3L_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196563.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTGIKGMLQNGV"
     gene            complement(24005..24358)
                     /locus_tag="ACGI3L_000837"
     CDS             complement(24005..24358)
                     /locus_tag="ACGI3L_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1375 family protein"
                     /protein_id="HFG9196564.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISSFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(24375..29696)
                     /locus_tag="ACGI3L_000838"
     CDS             complement(24375..29696)
                     /locus_tag="ACGI3L_000838"
                     /inference="COORDINATES: protein motif:HMM:NF012632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196565.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFIKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGNGNTMLIDNKGILKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDIFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHVFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYICNDVSIIVKNDNTCYVCGFVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNVIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAESNEPQA"
     gene            complement(29713..30696)
                     /locus_tag="ACGI3L_000839"
     CDS             complement(29713..30696)
                     /locus_tag="ACGI3L_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFG9196566.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKVD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(30697..31395)
                     /locus_tag="ACGI3L_000840"
     CDS             complement(30697..31395)
                     /locus_tag="ACGI3L_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HFG9196567.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(31392..32444)
                     /locus_tag="ACGI3L_000841"
     CDS             complement(31392..32444)
                     /locus_tag="ACGI3L_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFG9196568.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEINISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(32437..32865)
                     /locus_tag="ACGI3L_000842"
     CDS             complement(32437..32865)
                     /locus_tag="ACGI3L_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HFG9196569.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            complement(32865..33191)
                     /locus_tag="ACGI3L_000843"
     CDS             complement(32865..33191)
                     /locus_tag="ACGI3L_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HFG9196570.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(33207..34736)
                     /locus_tag="ACGI3L_000844"
     CDS             complement(33207..34736)
                     /locus_tag="ACGI3L_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9196571.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLNVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(35018..35440)
                     /locus_tag="ACGI3L_000845"
     CDS             complement(35018..35440)
                     /locus_tag="ACGI3L_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HFG9196572.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(35440..37893)
                     /locus_tag="ACGI3L_000846"
     CDS             complement(35440..37893)
                     /locus_tag="ACGI3L_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196573.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MILAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     VWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(37893..38060)
                     /locus_tag="ACGI3L_000847"
     CDS             complement(37893..38060)
                     /locus_tag="ACGI3L_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196574.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(38087..38533)
                     /locus_tag="ACGI3L_000848"
     CDS             complement(38087..38533)
                     /locus_tag="ACGI3L_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9196575.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(38659..39087)
                     /locus_tag="ACGI3L_000849"
     CDS             complement(38659..39087)
                     /locus_tag="ACGI3L_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFG9196576.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYIGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(39101..40165)
                     /locus_tag="ACGI3L_000850"
     CDS             complement(39101..40165)
                     /locus_tag="ACGI3L_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFG9196577.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(40170..40613)
                     /locus_tag="ACGI3L_000851"
     CDS             complement(40170..40613)
                     /locus_tag="ACGI3L_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFG9196578.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(40862..41302)
                     /locus_tag="ACGI3L_000852"
     CDS             complement(40862..41302)
                     /locus_tag="ACGI3L_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196579.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(41407..41604)
                     /locus_tag="ACGI3L_000853"
     CDS             complement(41407..41604)
                     /locus_tag="ACGI3L_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196580.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            41773..42093
                     /locus_tag="ACGI3L_000854"
     CDS             41773..42093
                     /locus_tag="ACGI3L_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9196581.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            42175..42681
                     /locus_tag="ACGI3L_000855"
     CDS             42175..42681
                     /locus_tag="ACGI3L_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFG9196582.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            43382..44137
                     /locus_tag="ACGI3L_000856"
     CDS             43382..44137
                     /locus_tag="ACGI3L_000856"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9196583.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(44280..44708)
                     /locus_tag="ACGI3L_000857"
     CDS             complement(44280..44708)
                     /locus_tag="ACGI3L_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFG9196584.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(45129..45329)
                     /locus_tag="ACGI3L_000858"
     CDS             complement(45129..45329)
                     /locus_tag="ACGI3L_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9196585.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(45512..46666)
                     /locus_tag="ACGI3L_000859"
     CDS             complement(45512..46666)
                     /locus_tag="ACGI3L_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HFG9196586.1"
                     /translation="MKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNMEEKVM
                     ESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYENEVKK
                     MKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQKDKENA
                     FRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGVELQLT
                     DEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGRFKKNS
                     IWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFVGYEKK
                     GRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            46917..47738
                     /locus_tag="ACGI3L_000860"
     CDS             46917..47738
                     /locus_tag="ACGI3L_000860"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HFG9196587.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYNRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(47814..49202)
                     /locus_tag="ACGI3L_000861"
     CDS             complement(47814..49202)
                     /locus_tag="ACGI3L_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HFG9196588.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(49337..50095)
                     /locus_tag="ACGI3L_000862"
     CDS             complement(49337..50095)
                     /locus_tag="ACGI3L_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HFG9196589.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(50097..50813)
                     /locus_tag="ACGI3L_000863"
     CDS             complement(50097..50813)
                     /locus_tag="ACGI3L_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HFG9196590.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIASILIILLFMWQIPLCMFLASKFGMFVTVLTNMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(50815..51522)
                     /locus_tag="ACGI3L_000864"
     CDS             complement(50815..51522)
                     /locus_tag="ACGI3L_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9196591.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            complement(51638..52174)
                     /locus_tag="ACGI3L_000865"
     CDS             complement(51638..52174)
                     /locus_tag="ACGI3L_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9196592.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(52276..53346)
                     /locus_tag="ACGI3L_000866"
     CDS             complement(52276..53346)
                     /locus_tag="ACGI3L_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFG9196593.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(53339..54397)
                     /locus_tag="ACGI3L_000867"
     CDS             complement(53339..54397)
                     /locus_tag="ACGI3L_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFG9196594.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINENSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(54384..54716)
                     /locus_tag="ACGI3L_000868"
     CDS             complement(54384..54716)
                     /locus_tag="ACGI3L_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9196595.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            54915..56036
                     /locus_tag="ACGI3L_000869"
     CDS             54915..56036
                     /locus_tag="ACGI3L_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196596.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(56164..58062)
                     /locus_tag="ACGI3L_000870"
     CDS             complement(56164..58062)
                     /locus_tag="ACGI3L_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HFG9196597.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            58377..59153
                     /locus_tag="ACGI3L_000871"
     CDS             58377..59153
                     /locus_tag="ACGI3L_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFG9196598.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKSSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMWKTNQFTLENVKQRKNK"
     gene            complement(59245..59997)
                     /locus_tag="ACGI3L_000872"
     CDS             complement(59245..59997)
                     /locus_tag="ACGI3L_000872"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFG9196599.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(60158..61108)
                     /gene="galT"
                     /locus_tag="ACGI3L_000873"
     CDS             complement(60158..61108)
                     /gene="galT"
                     /locus_tag="ACGI3L_000873"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HFG9196600.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            61493..62689
                     /locus_tag="ACGI3L_000874"
     CDS             61493..62689
                     /locus_tag="ACGI3L_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFG9196601.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(63024..63476)
                     /locus_tag="ACGI3L_000875"
     CDS             complement(63024..63476)
                     /locus_tag="ACGI3L_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9196602.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(63787..65232)
                     /gene="purB"
                     /locus_tag="ACGI3L_000876"
     CDS             complement(63787..65232)
                     /gene="purB"
                     /locus_tag="ACGI3L_000876"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFG9196603.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(65376..66284)
                     /locus_tag="ACGI3L_000877"
     CDS             complement(65376..66284)
                     /locus_tag="ACGI3L_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9196604.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            66541..67365
                     /locus_tag="ACGI3L_000878"
     CDS             66541..67365
                     /locus_tag="ACGI3L_000878"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFG9196605.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            67405..67935
                     /gene="lepB"
                     /locus_tag="ACGI3L_000879"
     CDS             67405..67935
                     /gene="lepB"
                     /locus_tag="ACGI3L_000879"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFG9196606.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(68017..69798)
                     /locus_tag="ACGI3L_000880"
     CDS             complement(68017..69798)
                     /locus_tag="ACGI3L_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFG9196607.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(70180..72516)
                     /locus_tag="ACGI3L_000881"
     CDS             complement(70180..72516)
                     /locus_tag="ACGI3L_000881"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9196608.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYSYDSVFLVSTKTNNYYHFNGLDRNLSANNSENQWYYTFLKNDDEYSLNVDNDEA
                     SNNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYNDKFDVVARLIDDKGFVQ
                     LAVDKTGHENINFFENSSSDLSNSKQLILNNKKEQKSFWYSSEKSKSYIVCQYIPSLK
                     WHLVLENDFTLMIKQLHLQFFKGIAVIVLIIIFVLFTITHVLKKYKNQIIKLSVSQKL
                     EYQKLLSKSTEGLYENIFEIDITNNKAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKRYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDNFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     NNNYVLIDKLERFCSKINQKKFVEQAEFSIACSIGVAMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHIFSEDSIDSISFHIDSRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSIGFDIFSPVLQDDLQMVLDTLREAISKRETFEIVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISSINTLLENK"
     gene            complement(72830..74371)
                     /gene="rny"
                     /locus_tag="ACGI3L_000882"
     CDS             complement(72830..74371)
                     /gene="rny"
                     /locus_tag="ACGI3L_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFG9196609.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(74547..75593)
                     /gene="recA"
                     /locus_tag="ACGI3L_000883"
     CDS             complement(74547..75593)
                     /gene="recA"
                     /locus_tag="ACGI3L_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFG9196610.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
BASE COUNT        25005 a        12575 c         8542 g        29646 t
ORIGIN      
        1 ataaatttct atttttccct taaatcattc acattctttc taagctacat aagatttttc
       61 tattatttct ttttgagttt aatttagcat tatgttgagg aaaaaacatt tcatgcattt
      121 taataaatta aatctttctt ttattctgcg attttataat aatcaattta acttaaaaat
      181 aatacctaac tattttaact atgttaaact agtaaatgta accacttata tgttacaatt
      241 ttatataaac atcagatata aaaactatat aaataaatga cacatagtgt tatatttttt
      301 aataccaatt tagttatttt tcagttacag atttaataat aattaatagt aagacataat
      361 atttttatgc cctttattga ttatgtattt tctgttatct gttattatca tcaataataa
      421 acataagggg gtatatatta tgaaattgta tttaagtgct gatatagaag gtacttgtgg
      481 tattgtaaat tgggatgaaa caaaacttga atgtgaattt tcgcaacact atagaacaca
      541 aatgagtaaa gagataacag cagcatgtga tggagctact caatctggtg tacatgaaat
      601 acttgttaaa gatgcacatg acagtggtag aaatattaat ccaaatattt tacctgaaaa
      661 cgtcaaaata cttagaggat ggaccaaaga cccactagtt atgatggctg gaattgatga
      721 aagctttgat gcatgtatat tcaccggcta tcactctgga gctacttgta atggtaatcc
      781 actttcccat actatggata ttgattatga ctattttaaa ataaatgatg aaatagcatc
      841 tgaatttact ataaatgctt atattgctgc atattataat gttcctgtag catttttaag
      901 tggagatgaa atgctttgtg agagtgcaaa aaaactaaat ccaaatatag tcactgttcc
      961 tgtgtcaaaa ggaattggaa atggttcaat ttcaatccat ccaaaccttg cactaaaaaa
     1021 aattgaaaaa ggtgtcaaaa aagctttatc tggagattta tctaggcact taataaaatt
     1081 gccagataaa tttaagatag aaataaaatt tagagaacat tataaagctt ttaaggcctc
     1141 tttttatcca aatatgaaaa aaatagattc tcaaacagta ctatttgaaa cagaggacta
     1201 ttatgaattt ttaagaatgt tattatttat ataaatttca tatcataaat taaggagttg
     1261 attaagataa gtaataaaag aaggattcct ttaggcgaat ttatttctgt atttttattt
     1321 tttgctgttt tttttggtat aactttttgt attttcacgg ttataggaat tggcttctta
     1381 tcattcttag gatttgaata taaatctctt ggagctgtat taattttctt tttaatatat
     1441 ttttgtataa ccactccaat tgattttcta tgcactacta ttttagatat attcagatat
     1501 gtaaacaaat taccatactc aatatataaa ctttgcgaat ttataattga ttttatacta
     1561 acttttctag ctatgaacat aattgatacc tttatggatt cagtaacgat tcctttaagt
     1621 acagaaatct tattcgcttt actttcttat cttttatcag aatgtatgga tttttttgat
     1681 agggataaga aaaaacctta ataaaaaaga tagattcctt aatagaacac atattttcgt
     1741 atttctatta tttaatctat ctttatttta tttaataaat ttttattaat taaaatatag
     1801 tttcttctat ctccttagtc atttgcttag cactatcaaa aaattcttct atatacacta
     1861 cttcatcact gaccctagaa tattctgctg caaatgccat tacatgactt tgtatagctt
     1921 cttttgctgc tactctaccc ttttctagtt ctttatttga aactaattta ataaattcag
     1981 ctataagatt tctatcatat tcctctacca tattctgttg atttgatgga ttcataacta
     2041 tttcttcgtt ttttccaaat tctttaattc ttatctcatt tttatttaaa tccccaccaa
     2101 cttcaccatg gctaaacatt aactttatag ttcttccatt ttctttagta aatgcacata
     2161 aattaaaagt agccgtcact ccattttcaa actgtagtat atttaccata ttgtctacaa
     2221 cattattatc acatctgtaa acacatcttc catatggact tgtcttaagt atatttaata
     2281 gattctcttc agttggattt atgtgaacag ctctatttat acttctatct ttttctaaat
     2341 aaattctctt tgctgaatat ggacattttt tttcaactaa acactgaaga caattttgtg
     2401 ccatctctcc actagcattt tggttattaa gatgctttaa gcttccaaat gcagatattt
     2461 ttttgcatct acttcctact aaatataaca aaatatccat gtcatgacaa ctctttgcta
     2521 aaattaaagg gctggtttca ttgctatttc tccaattccc tctagtaaag ctatgtgcaa
     2581 aatgccaata tcctatattt tcattatatt gtatactaac tagctctcct aattttttgc
     2641 tttctacaat ttcttttaat ttattataaa atggagaata tctcagtaca tggcaaatca
     2701 taaaaatctt atctttatac ttatcacaca agtcatctat atgtaccaga ccatctaaac
     2761 tattagacat tggcttttct aatagtacat gataaccttt ttcaagagct agttttgcta
     2821 catcataatg tctatcatca tttgtagcta ttattactgc atctgccatc ttgtcatgtt
     2881 taaaaaagtc ttctaaagtt tcaaatacat ttttactatc taggttatat ttttgtgtaa
     2941 atagttctcg tcttcctttt ttaggttctg ctacagcaac tatttcacat acatcagaat
     3001 tttcataaat atatggagca tatgcatacg ttcctctatt acctgctcca atcacagcaa
     3061 ctttcacttt ttccatactt taatttatcc cctttatatt atttatacta ctctattata
     3121 gtctattttt acagacattt ggatattttt aataaaagaa acagcagtta taatttttca
     3181 attttaactg ctgttataag ttaatatacc aaacattttt aattaaattt tctttaattt
     3241 taatacaaag acttaaatat tcaatacaaa ttataaaaac acttttatct agtttacttc
     3301 ttcttttctt tgtctaattt atctaacttc ttattgtata aaaacatata aaatgctgcc
     3361 gaaaatacta ttaaatatcc aacaacactt aacatatctg gatagacatt gaataagaat
     3421 atacttaaaa ttgctgaaaa gattatatta ctatagtcaa atatagagat ttccttagca
     3481 ggtgcatatt tatatgctag agttattcca aattgaccta gacttgcaaa tactccccct
     3541 agtaatagat atataagttg cataagggtc attggttcat atactgcaaa agcaattggc
     3601 cctacagtaa ctaatgaaaa aactgaaaag aaaaatacaa ttgtatagta atcttctcta
     3661 tctccaagaa ctcttaaaca agtatatgcc attgctgcaa atacagctcc tgcaattccc
     3721 ccaagatatg gaattatttc tacactaaat gttggtttta ttatgaataa agctcctata
     3781 aatgcaatta taatagctcc tatctgcttt acatttattt tttcttttag agcaattgca
     3841 caaaatatta ctacaaggaa gggactcatt ttatttagca tattagcatc tgaaagcatc
     3901 aacttgtcaa ttgcatagta gttaaatata actcctagag ttccaaatat tgacctatat
     3961 aaaagtactt ttaaattttc ttttttacca gttagacttc ctttatgttt tatgataagc
     4021 caaaaagcta ttatagctga taccagattt ctaaagaaca ctttttgaaa acttggtaaa
     4081 tctccagcta gctttacgaa tgcagacatc attgcaaagc caagcgctga tgctattata
     4141 aacattatac cttttattcg atttgatttg attgtgctac tcatacgtac ctcttttcta
     4201 tataaatgta taaaaccata ttaattaaaa acttagctta tacattaaat aataattatc
     4261 taaatattcc aatttatact ataattaaaa gtgtaaacta tgtcaagtaa ctaataaatc
     4321 ttttcaatta ataacaataa taattatagc taaaaagtta tatgttttta tggattatta
     4381 tcagaatata taatataatt ttatatagta tagacttttt ttaatttatt atttagattt
     4441 ttaatagatt ttttaactat ggaggtattt aaaatatgga aataaagaga tatgaaggaa
     4501 ctggaagaat gagtagagct gtagttcata acaatacagt ttatttatgt ggacaaactc
     4561 atgctgaagg aggagtaatt gaacaaacaa ctgaagtttt agctaaaata gaagatttat
     4621 taaacaaata tggttcagat aagcaacatt tgctatctgt tactatttat ttaagagata
     4681 tgaaagactt tgaagctatg aactctgttt gggatgcttg ggttgaaaaa ggatttgaac
     4741 ctgctagagc ttgtgttgaa gctagacttg ctagagagca tttgttagtt gaaatgagcg
     4801 ttgttgcagc tacaaaataa tcaatttagc ttataggagg ctatctcaaa acagagagat
     4861 aagcctcttt ttcattgttg aaatgatgaa aatacatttg attttgtata aaagaaagtg
     4921 tctcacgaac taaaaaattc attttgagac acctcctcac tatttaatct atataaattt
     4981 acttattctc tattggcaat atcaatttag atggatattt acctccatga taaatcgtat
     5041 tctttgcttc tatatattca atactattat atccctctgt cgtgttgcta ttttggaaaa
     5101 taaagttttt agcactagac gttatatcta gtctaatttt atgaccaact ttaaacgtgt
     5161 ttgatatttt tgaagttata atcgtaaact tataaatctc tccttcttcc ataaactctg
     5221 acttataaaa actatttcta aatctagcac taagtatacc atcagctaat ttaattgaat
     5281 ttccatctaa atccacgtcc ataattttta taacccagtc agtatctttg gcagaacttg
     5341 atgcaaaaaa ctctaacttt atatcacctg ttacagtaaa ttcttcacta aaagcatctg
     5401 atgtataaca caacatatca cttctttttt ctaaatcttt gtagttattt ggaactccaa
     5461 cttcattctc tgacatatca attagttgta ctgatgggtc ttttggatta tatatataac
     5521 tatcatactt ttcttctaaa ccattatcaa atactaatct accatttcct aaagatgtgt
     5581 tagcatttcc atcacttatt agatacatac ttttatctat cttatttatt attggccaat
     5641 tttcttctgt cttccactta ttagaaccta cagagtaata ctctactgga gcagtcgtat
     5701 ctatgttatt ttctatacct tttaagtatt tatcaaacca taatagataa ttataatcca
     5761 aatcatatct taatgaacta tttcctaaag aaataccatt tatatctctt aaagtatttg
     5821 aattatgcat ccatggacct agaatagcct ttctctttcc tttttcatag tcctttataa
     5881 catctaaggc ctctgtagtt cccatactat tatcatcata ccacccagat acaaccaatg
     5941 caggtacatt tattttatct ttttgtaaat gccaatccat caaatcccaa tactcatctt
     6001 tttctactct ctttaaccat tcttccagaa attcaattct atatccaaga gcttcaacag
     6061 gtatattttc tattggtcgt atgtttaaaa catcatccca atcatctctt accattttgc
     6121 ttctatcaac tttatttctt gataccataa atgcccatgc aagcatacca gatacaaaag
     6181 ctcctccttt tcttggtata tcaataaaag ggcttcctga tgttactata ctaactaaag
     6241 ctttaagatg cttattgcct gaagatgcag ctgcccattg gacataacca agatatgatg
     6301 ctccaagcat tccaactatt ccacttgacc attcctgtga tactatccaa tttatggtac
     6361 tatctccatc ttccctctca tgaatcatag gttcccactt accttctgat tcatttcttc
     6421 ccctaacatc ttgtattaca acagcatatc ctctttgtac atatttataa tatatttctt
     6481 tatcattttc ttttccatat ggagttctca taagaattgt cggtgctttt ttggtagaat
     6541 ctacaaaatc agggagatat acatctgtag aaagttttat accatctttc atatcaatca
     6601 tataatttcc accaaatctt atagaatata tctcttcatt tttatgagtt ttttcccatt
     6661 cttttaatac agtatactct tcatatccat ccataattaa tatagtacaa gtttctctgg
     6721 ataaacagat aaaacctact attttattat ctacaataat tatatctagt gggaactttt
     6781 tgtttctttg aacccatata tattcattaa gtttagaatg cgtttctcct aagttattta
     6841 taactgtgtc tttatctgtg tttactaagc ttttagtata tacatcaaaa ttattaaata
     6901 aagactttaa atctattttt gtaagattta aatagtatgt attttcttcc ttgcttattg
     6961 gttttaaact ttctatttta tttgtaaaag gattcaactt ttcaattaat aaatctccat
     7021 caaagattac atttccactg tatagtccag atatgtataa tttaaatttt atcaattaaa
     7081 ctccccccta taatcctaga gacatcttta ttgcatatgc cactgatata cctgcataat
     7141 ttcctaatac tccaccaatt actcccatta cgactgctac acttacaagc gaattccact
     7201 ttgcagaagc agctactaaa gctgaagtag gaccatcagc aattgctcct actatagaaa
     7261 gtattacata ttgatacttt atctttaaaa gtctagttat gcctaaatgg aaaacaaatg
     7321 aagcaaaaat tatgctaaaa cagtaaagtg ttatagtaaa agttgaacct aaaaattctt
     7381 ttatatctac tgaaaaacct attgtacata aaaagaataa tgcaacaaat aatcctaaat
     7441 ctaaatttcc ctttagtttc tttactggct ttaattgagc aattataatt gaaattgttg
     7501 taactaaaag tattcttgct gcactactaa aactcgaatt gaaatatcca gcaagtattg
     7561 ttgcaacttc tgtaacaaca aaacctatag ccaacatcca agctatatct ttaatactcc
     7621 attcttttga ctccataaat tcttcatttt gacaatcctc taattctgat tcttctacat
     7681 gatatggcca aagtttttta aacttctttg aattttttaa tattgctggt agagcaaaca
     7741 taaatatcaa tgttggtact ccaattacat agtctgctgc atttgctgca gcaagagttt
     7801 gtctacttac attaagacct gttccaatag ctgtaagatt agcacttcca ccagtatatg
     7861 tacctacaaa cattccagca accttccaac cttctgatat tttttctgca aatactaatc
     7921 caaataaaaa tgccatgata cttacagtta atacagctac aaaaattgca attaaaggtt
     7981 ctcttgataa ttttgtcatt tcttttaagt caacactcat caacattata gtcatagaaa
     8041 ctggaatagc atatgttgaa atagttccat ataactcagt acttactgga actactttta
     8101 agtttgaaag tattattccc attatgatta ttgtaagtgc tggtcctaag cttttaatgg
     8161 ctttgtatct ttgtaagtaa aaacccaatg caatcattga tgtcattaca gcaagtatac
     8221 tacctggatt tgaaaaaagt gtattcatat ttaacctcca aatttatcat aagtttactt
     8281 ctattcctaa acctggttta ttgacaagat tcataatatc tccatccatt acaaatcctc
     8341 cagatatacc ttctaattct tcacaaaaca taaaactatc aaggtcagct tctgttatgt
     8401 tctttttaga tgctattaaa tttgctgctg ctgttatacc aattctcgtt tccagcatac
     8461 atcctaacat acaatttact ccacttgcct cagctatgtt gttgattttt atagcaggat
     8521 atattccact tgatttcatc agcttaatat taaatgtatc aactgcattc ttttttatag
     8581 ccttaattgc atctattggt gaatgtaatg attcatctat cataattttt gtattacttt
     8641 tatttcttat gtaagcagta ccatctaaat cccaatgtgg aagtgcttgt tcaattgcat
     8701 caacattaaa ttcttctaac tttttgatag tatttatact gctatttacg ttccatcctt
     8761 gatttgcatc aattctaatt cttatactct ctccaacggc ttctctaatt aactttacag
     8821 cttcaatatc gtcttcagga tttatacctg ctttaagctt caatatccta aaaccttctt
     8881 ttactctttc taaagcttct actgccattt tttctggctt atctatactt atagtaatat
     8941 ccgtttggac tttactatca aatcctccaa gaactttata aaggggtgca ttcataattt
     9001 ttcctttaat atcatataaa gctatgtcaa tagctgcttt tgcagaagta ttacctataa
     9061 taattccatc catgattgta tgtatggttt caatatctag tgggtctttg cctattaact
     9121 cttttttaaa cataagcaat actgaaagaa cattatccaa aacttcacct gtaactgctg
     9181 caagaggcgc tgcttcgcca aatccacaat acccttcatc agtttcaatt tttaaaatta
     9241 tactttctcc atattcaatt actccaaatg aaactactac aggttttttt aatttaattc
     9301 taagcttttc aaatttgata tctgttatct tcatattacc ctccttattt tttgaagtta
     9361 taattcaatt tttaaaattt tatactttaa attatattat tacttcaata tatatgtcaa
     9421 gataatttac tgaaaattta ctcttttcca aaatataatg tgataatctt aattcaatta
     9481 atactcttct attaaatttt tttattatta ttttctttgt attaatttaa caataattca
     9541 ttttcataga cttttatttg gatttaatta aattttaatt gtcaaaatct actatgtatt
     9601 cttattgcca ctacttctat gttgtgctat aattactttg ttttaagcga atattttata
     9661 ttaattttat tatttggagg ttcttatgct aggtgaaaag atgagaaata taagaaaaag
     9721 caagaaaaaa acattaagtg atgtttccaa attgacagat ttatctataa gttatatctc
     9781 tcaaatagaa agagatgcta ttgaaccatc cttgtcttca ttgagaaaaa tcgctgaagt
     9841 tttagacact cctttatata tgtttatgga tgacaataat actgatgatt tagtcattag
     9901 aaaagaagat agagttatga tgaaatttcc aaagagtgaa atgttttacg agatagtatc
     9961 tccaatgcct acaactgagt ttacaccttc aattttattt gtagagtttg aacttaaacc
    10021 agaaagtgag gatgccaaag attatatata tcatgcatca gaagaaatta tggtggtaac
    10081 gagtggtgtg gttgatattt gtatgggtga aaaggtagtt agattaaatc caggtgactc
    10141 aacatttata aaagctaatg taccacataa aatcatcaat ccaagtaaag atacaatagc
    10201 tcgtggatat ggagttatat cacctccaat ttggccaata aaatctaaat aaactcaata
    10261 tgacacacct actttttgta gataatataa tagatttaaa tattgctttt attttaaaat
    10321 tgaagtattt atttaaattt aaaatattta ctcaaactaa aaaaatagct atttgactaa
    10381 tctaaaccat cttaattatg gtaaatagta aatagctatt tgtaagttat attataaact
    10441 ataataaaaa ttgtatttgt taaaattaaa ctgctatatc atttaatact tttgccttta
    10501 caactcttat atttttcata ctcttgtaga tatcttgaat cttatcttct tgctctctca
    10561 atagtctatg tgcttcatat atatctacaa gttcaaattt tactacatca tttggctttg
    10621 cttgtgctaa cttatacaaa tctacactta taacgttccc tatcttagta tagccaccac
    10681 tagtctgtct atctgataac attataatag gttttccatg accaggtact tgtatagctc
    10741 cataagaaat accctcagat ataatatctg ctccattaag gtgctttata ctctctccat
    10801 ctagtctaca acccattcta tctatttcat tcgtaacttt gtatttattt gataaaaatt
    10861 tctctacttc accgttagaa aaagcatcaa attgaggacc ttttacaatt cttagtacga
    10921 tttctgaact ataagttgga atatattttg aacttaattt tttatttatt gtaaaatctt
    10981 tttcctgaat aaaagtattt atataatcgc cttttttaag tgctctacct tcaaatccac
    11041 caattttagc tcttgtataa gttgacttac ttcccattgc aagtggaaca tctattccac
    11101 cagctattga cacataggct ctagtacctg atttcacacc tctaaatgat aatacatcac
    11161 ctggatttat ttgatatgac ctccagtttt gaatttcttt tccatttatt ttagccccta
    11221 aatctccccc agttactgct atttgcgtat attcatcaaa ggtaattgta ggacctaaca
    11281 ttaaaacttc taaagaagcc tcatcttcag aatttcctac taatatattt cctactctat
    11341 gtgcatactc atccattgct ccacatccag atacaccata ttgaccatag ccaactctac
    11401 ctctgtcttg tattaatgtt tggaaacctc ctaattcaac tttgaatccc atatatacca
    11461 ctccctgtac tataacgata tttaaatact taagttattt ttttcgattt ctataaattc
    11521 atctaatgtt attggaacaa attttataaa gtctccagct ctaagcaaaa tctgttcttc
    11581 tctattttca tcatataatt ttaaaggtgt cctaccaatt atttgccatc caccaggact
    11641 atcaatagga tatacaccag tctgggaacc tgctattcca acactcccac cataaatttt
    11701 agttcttggc acttctaatc taggtgtagc tattctttca tccataccac ctagatatgg
    11761 aaatccagga gtaaacccta gcatatatat caagtactct ctgcttgtgt gtatttttat
    11821 aacttcatct acagtgagat tattgtagct tgcaacgttt ttaatatcta taccaaaaac
    11881 ctcatcataa catactggaa tctcatgtat tttaggtttt ggtaatacta tactttccaa
    11941 attatcttct atttttttta aattctcaat caaactatca aaatctattt ctaatggatt
    12001 ataacttatc ataagtgacc tatatgttgg taccatttct gttacaatac ctttaagatt
    12061 cgatatttct attgctctca taaatgaaat tacttttttg tttatatctt ctgatatctc
    12121 atttccaaat tcagcaacca ctgccttatc ccctgatatc aagtatctag tttccataaa
    12181 tgtcacctct tctaaattaa gcaaataaag cacctaggct gctaagagaa gttattcctg
    12241 tatatgcaga tattaaaact actattaatc caaatattaa aagccatgta ggatgcttgt
    12301 aatctccaac aatatctttt cttttagatg ctataagcat aattcctaat gtgattggaa
    12361 gtatcaatcc atttaaagct cctgctaaaa ttaataaagt agctggtttt cctataaatg
    12421 ccattataag tgttgatatt gctataaatg ctattataaa atatttttca tatttatcta
    12481 taaaaggatt tagtgtcttt aagaaagaaa ctgatgtata agcagctcct ataactgatg
    12541 taattgcagc agaccataat acaagtccaa agaatttata tcctattgct cctgcactaa
    12601 atttaaaagc tgaagctgct ggattttctg ggtcaagttg aagacctttt gaaaccactg
    12661 ccagtattgc taaaaataaa agaactctca tcattgtggc aactaatata cccaaaagag
    12721 aagatttagt tatttctttt atattttctt ctcctgttat tccaccgtct attaatctat
    12781 gtcctccagc aaaagttata taacctccaa cacttcctcc aagtaaagtt attattggga
    12841 atatcagtcc ttttggattt tctggtttta ccattcttga tactgcctct ccaacaggag
    12901 gatgatttga tattgctaca tatccaacta taattatcat tcctaatgct aaaaatttag
    12961 ttatcttatc gactagagaa tttgaatttt ttgacataaa tacaaatata gctattaatc
    13021 cacttaatac agttcctaat gtcatattca tattaaacat tacattcata ccaagtgcag
    13081 ctccaccaac atttcctata ttaaaagcta atcctccaag agctactaaa aaagctacta
    13141 aatagcctaa tccaggtatt attttatttg ctatatcctg acctctaagt cctgatacac
    13201 caattactct ccatacattt acttgagccc ctataaaaag gattgttgta attaaaatta
    13261 caaatgaaaa attcggtcca aaatcttggg taaattgtgc agtctgagtt aaaaaccctg
    13321 gtccaattgc tgatgttgcc attataaatg cagcccctat aagtgctccg acatcttttt
    13381 tatttttagt tttatctgta atattttttg tactcatatt ttatctcccc ctcatgttat
    13441 cagtcttata ctatgttctc tgacgaacaa acttctatgt tttctaatgg acaaacttct
    13501 ataccttcta attcaaaacg ctttcttatt tctttgacaa actctattgc ttttggattg
    13561 tccccatgta cacatataga atctgctttg atatgtataa cttcacctgt taaagtttct
    13621 acagttcctt cttttaccat cctaacaacc ctatctattg catgttttgt atcatgtata
    13681 actgctcctt ctacatttct tggaaccaaa aaaccattat tatcataagc tctatctgca
    13741 aatacttcat ttgcaaacct aagtccaatt tctttagcag aatttatcat ttcactatta
    13801 tatagcccca acagtataat atctttatcg acttcatata tagcttcaca aatccccata
    13861 gctaactctt tatctttagc tgccatattg tataatgctc catgtggttt tacatgttgt
    13921 atattacatc catttgaact tgcaaatgcc attaaagcac ccagttgata ttttgtataa
    13981 tctttagctt cctgctttgt tattttcatc tcacgtcttc caaatcctat taaatctagg
    14041 aaacctggat gtgcgcctat tttcactcca ttttttttag ctagctgtac tgttttttcc
    14101 atatgactag ggtcacctgc atgaaaccca caagctatat tggctgatga aatatatttt
    14161 aaaacttctt catctaaacc aatcttatac gttccaaaac tttctcctaa atcactattt
    14221 aaatctactt tatacaattt atgacccctc ctcgctaaca ttttgataga ataagtagtt
    14281 ttaattttta aattttgttt attttatata ttgcatgaaa tattttatca cttgtattca
    14341 attttatttt tgcaactatt ctattgcatt taattaatat aattttacca tttaaggaat
    14401 atttttgcaa ttattttaat tgaacattca tttgtatttc tttttcaaaa aatcttttta
    14461 ccatttttta gttaataatt aattattttc acttaaaata agggctttaa ccttcatttt
    14521 taaagtattt ttcattttta atcactttat atgcaagaca gaatcatttt tcttcattca
    14581 tttgtttctt tcatctatat aattatcatt ctttgtaagt aaaatatctt tatattttta
    14641 taattaattc tttatatagt tttaagtata ataaaatcat gtatactaaa tgcatgttaa
    14701 aatattattt taaaacatgc acaatatttg tacatattgt agacatataa acctataaat
    14761 tatacaatag tattgttaag attatatatt tttttaacat aaattttgta ttgggggaaa
    14821 aacaatggat aaaaactata cgatgccaat ataccaaaaa atagcgttgg atattgcaaa
    14881 taaaatatac acgggtgaaa tacaagagga ttcagtacta tttggacgct ctgttttggc
    14941 tggtaaatac aatgtatctc cagaaacgat aagaagagct gtcaaaattt tagaggacat
    15001 tggcgttgtt aaaagcataa agggtaaagg tgttattgta ctatctccag acaaagcttc
    15061 ttcttttata aaaaaatata gagatattac aaatatatca tcatataaat caacacttta
    15121 taatttaata gatactaaat ctaatttaga aaatgaaata ttagatacta taaataaaat
    15181 tttagactat tctaacagac ttgaaataat caatccttta gtgcccgttc agttcaccat
    15241 aaattctaat tgcaaatata ttggtcaaac agctgcacaa actaaatttt ggcaaaatac
    15301 aggtgctaca atagttgcaa ttaaaagagg tgaagaactt ataatatctc ctggaccata
    15361 tattgaattt ttagaaggag acattctctt agtagttggt gaccaacaca tttacaattc
    15421 tataccaatg tttttatatg aaaacgaaaa ataaattata taatttagtg tgattatata
    15481 aaaatgcaag attaacaaca aaaaaagagc ttcatatttt acataaagct ctttttaaat
    15541 tcaaataaat ttaactttga ttaattttta aatatccaat tcatcttctt tttcccagct
    15601 taaagctctc gatacagctt ttttccatcc tttatataat ttacatctct tctcttcact
    15661 catatttgga ttaaactctt tttctactga ccactttgaa gtaatttcat ttcttccaat
    15721 atagaatcca acagacaacc ctgctaaata agcagctcct aaagctgtag tttctactat
    15781 tttgggtcta tctatatcta catttaatat atctgattga aattgcatta aaaaattatt
    15841 attacttgct ccaccatcaa cttttaatga ttttagtttt aattttgaat cgttttgcat
    15901 tgcttctaaa acatcctttg tctgataagc aattgattcc aatgtggctc ttactatatg
    15961 ttcttttttt gctcctcttg taagtcctaa aattgaaccc ctagcataca tatcccaata
    16021 tggagctcca agacctgtaa atgctggcac tacatataca ccattagtat cctctaccct
    16081 atttgcatac atttcactat cttttgcaga ttcaattatc tttaattcat ctctaagcca
    16141 ttgaacagat gctcctccaa taaatatact tccttctaat gcatatgtta cttttccatc
    16201 aactccccaa gcaattgttg taagtaaccc atgcttagat ttaactatgt tactgcctgt
    16261 attcataagc aagaaacaac ccgttccata agtatttttt gcagtacctt cttcaacaca
    16321 attttgacca aataatgctg cttgttggtc tccagcacat cccgcaatag gtattttagc
    16381 tcctgataac atgcgctcat ctgtatgacc ataaacatag ctagaaggtt ttactaatgg
    16441 caacatgctt attggtatgt ccaattctcg taatatatcc tcatcccatt ctaaatcatt
    16501 tatattgtac atcattgttc tagatgcatt tgagtaatct gttacatgta cttttccacg
    16561 agttaaattc catattaacc atgtatctat agttccaaat aataactctc cttgttctgc
    16621 tttttcccta gctccttcta cattatctaa tatccatttt acttttgttg ctgaaaagta
    16681 tgcatctatt aaaagacctg ttttttcttt tattgattct tccaatcctt tatttttaag
    16741 ttcatcacat atttctgacg ttctcctaca ctgccatact attgcgttat aaataggttt
    16801 accagtatac ctactccaaa caaccgtagt ctctctttga ttagttatcc ctattgaagc
    16861 aatttcttct ggtcttatac ctgctgtttc tataacttct ctcattaccc cactttgtga
    16921 cccccatatt tccatagggt catgctctac ccatccagct tttggataaa tttgattgaa
    16981 ctctttttgt gcaattttca ctatttcgcc ttttttatta aatagtatag ctcttgaact
    17041 ggttgttcct tggtctaatg ccattacata cttcttttcc atcaccatat tctccttatc
    17101 atataatatt taatttatta aaaagaaaaa tttaatatca catatttcaa taaataatca
    17161 tacttaagta caaatttaat ataatagata tttagtaaga agacacttat tttctatcat
    17221 atctatataa taatattata cattatagct tacatattga ttaataaatt ttaaaggagt
    17281 ataataaaca gtgttcataa taattttaat aaaagaggtg gtaatatgcc aaagatttta
    17341 gaaaatgtaa aagaagatat attaaaagtg tctcgggata tgattttaga agaagattac
    17401 tcgaatatta gcataaggaa aatagctcaa aggtgtggta taagtgcagg tacagtgtat
    17461 aattacttta attcaaaaca agaaataata gaatatatca caaaatctga atgggattta
    17521 ttgataaggc gaattgaata ctccaataaa aacactgaag attacataaa aaaactaaac
    17581 attattttta ctgaaataag aaattttata aacaaagttc ataatatcca atacaatgac
    17641 tttttaaaca cttttgaaac agagagattt tttgaaatga aaaaacacaa agacgacttt
    17701 catgaacagc tttcaaataa agtatatgaa gctttagaaa aagaaagttt ttttaataat
    17761 gacaaattag tatgcaatat cataataaaa atgttttttt catattcaac atatcttcat
    17821 atagaatttg aagatttaaa accctatatt gaaaaattaa tacattaagg tggtgtttac
    17881 cttgaatcat aatactagta ttaagaacaa ggacagtaat ccaaaaatat ttttagtact
    17941 tacgctttat ctattaggta tatttatggg agctattgat actggaatag tatcaccagc
    18001 aagaacgatt atacaaaata gccttggagt aaatgaaaaa acgggaattt ggatgattac
    18061 catatacaca ttaacatacg cttctgtaat tcctatctct ggaaaattag cagataaaat
    18121 aggaagaaaa tatgtgtatc tagttagtat atttctattt ggtagtggtt cattaatatg
    18181 tggattatca tcactatttt ccaatttcta tattttatta attggtcgtg ttattcaagc
    18241 aattggtggt ggtggaatca tgccaattgc tacagcagaa tttggaacta ccttcccaga
    18301 aaataaaaga ggcatggctt taggtttagt tggggcaaca tatggtattg ccaatatttt
    18361 aggttcaagc attggtagca caattctaag tatctttgga actcaaaatt ggaagtggct
    18421 attttttgta aatcttccaa tttgtttaat catacttatt ggtggagttt tctgtattaa
    18481 aaacaataag tctgaatcta aagaaaaaat agataagctt ggtacattga tgttgatatg
    18541 tataatcgta tcactattat atggtcttat gaatatagac ttttttaatt ttaaaaattc
    18601 tatacaagat atatcagttt atccatactt attgacattt attgtactta tacctatttt
    18661 catatttatt gaaaatagag ctaaagaccc tattttaagc tttgaatatt ttttaaatcc
    18721 gagaatattg atagtactta ttttatcttt aattgttggt attggaatga tgggtatggt
    18781 attcgttcca cagtatgctg aaaatgcatt aaagataaat gctggttctg ggggatattt
    18841 tgtagctata ttgggattat ttgcaggtat tgctgctcct ttaagcggaa gacttattga
    18901 caagtttggg gcaaaaaaaa tactattact aggattttct gtatctatga taggctctct
    18961 ttacctagtt ttaattgctc taaaaaccaa tactgtattt agtgtatgtg taagtttaat
    19021 atttatggga ttaggaatgg gatttactat gggaactcct ctaaactata tgatgttatc
    19081 aaatacaaga ttagaagaat ctaattcagc acttgcaaca ttatccttga tacgctcaat
    19141 tggtacttca atttctccag ctataatgat tggatttata gcacatgcag gattatctgt
    19201 gcaagataat attatggact tagttggaaa gccctcaact cctaaaatag ttcaacttga
    19261 agaacttgaa aacatgatag atgacttaaa atcagaccct gaaatggcaa aaaatttaaa
    19321 aaatgtctct atcccaaata tgaatgatac ttcaaatata aatatggaca tgacaggtgg
    19381 caaacttcca aaatccttac ttaataaagt tcagtcagca gatacaacca acattaccaa
    19441 tataacaaaa gaaatatcaa caacaatgtt tgatgaaaaa gttccatcta taattactaa
    19501 aatacagaaa aatgtacaaa aaggaataga tggaacacaa agtggaataa acggtattga
    19561 agatggtgaa aataaactaa atagtggtat taaaggagtt caaactggta ttgacaatat
    19621 ggtaaaagct agagctggta ttaatcaagg aatagatggt gtaaaaaaag gtattgctgg
    19681 tgttgataaa ggtataaaag gtatggaaca aggtcttgaa aaacaagatg aggccatcaa
    19741 ggaacttaca actgcttata ataaaatacc tactacagaa aaaactccta ctgataacga
    19801 aaataactca aatgaacaaa accagagtaa taccagtaat tctgaatcag acgacactaa
    19861 gaatgattct acagaaaata agaataacaa ttccagcgag aataaaccaa atgtaaatga
    19921 acaaaaagaa agtttaaatg ctcaaataca gcaactaaaa aagacaagag atgacttaaa
    19981 tacaaagtta caaaaaaata aaactcaaaa gaacgaatta agtaaaaaac taagaacaat
    20041 ggaatctcaa aagaaagagc tacaaagcaa gttaaataat tctataagcc aaaagaaaga
    20101 catggaaaaa agccttgata caatgcaaca gcaaaaaaaa tcactccaag cagttttagc
    20161 aaagacacaa gaggtaaaaa ctgaaatacc aaaggctttt gataaatcaa aattggatta
    20221 tataaattcc atagaaaata atagaacaaa aatagaaaac acactacaat ctactctaaa
    20281 ctcaggattt aaacagatgt atataacagt attctgtgta aatctactag catttataat
    20341 attattgttc tataaagaaa ataaaactag ataaaagagt gttatagtat tatattgtaa
    20401 atttatctta ttcttaaata ttttattcta aagaataaat tcataaaatt tttgtaattg
    20461 attaatataa attacaatat aatactattt ttctcttaat ctttttctct tttacagaca
    20521 atcaaaaagc aatcttagtt tatcgaaata aatttataca atctattcat acaccccttt
    20581 acatttatat aacaattaaa cctattgtta tatatacaaa tcaaaataaa ccatatattt
    20641 tcaactataa tatgttaaaa tcatattatg agcatattaa tttaagcaaa atgtcattta
    20701 gactttaatt tagtagtttt atattataaa tttatatatt tttaatttta aatgtcattt
    20761 agacattact cataaaaaga aaggagtgta ttttgtggat actttaggaa aaagaattgc
    20821 ttatttgaga aactccaaaa aacttactca gcgcaaactt atggatattt taaaatttga
    20881 aaacttaggc aagtatgaaa caggagatag aaaacctaat tgtgatatac taatgtcaat
    20941 agctgattat tttaatgtta cgactgactg gcttctctat ggtaaagaga aggtaaatgt
    21001 caatagtagt gtaaaagaag ataaagaaga ttacttacat gttactaatg atgaaatgac
    21061 gatattaaat ctatacagac aactaaacga acgtgataaa ataaaaatag aaggaatact
    21121 tgaacttaag atatctgaat ataaagactt aaaaaagcat tcctctaata ataatgaaga
    21181 taaaatggtt taaacataca taatttgata cgattttaca tcatctatta accttctttt
    21241 tttgtagtat attactaaaa tatggatatt ggattattta aaaacaagta tagtctaatt
    21301 tcaagcacat ttataatatt tagattatct tatccatatt ttagtttaag tactttgaaa
    21361 aatataatac atctctatgt ataacttata ttcctaagaa atgcattact catgttttta
    21421 attcttccaa catctttcta tacacaattg tacatccttc ataattcccc tctttaagaa
    21481 ggattgaaca tgtactagaa tatttagtta aagtatttaa tctttccata tttaagcttt
    21541 ttatattact gagtgctgta ataaaatcat caattgctct acaacactct ataaccccat
    21601 ctgaatccaa tttacacaca agaatattca cctactttat atactattta ttaatcatct
    21661 tctgaatatt ctatattaag taattgataa attgatgatt tatatttttt acctgttctt
    21721 cttccattta aaatagctga caaatagttt tcattaacac ctattttctt cgctaattcc
    21781 ctttgagtca tatttaattc aataagtctt tgcttgactt gcactcccaa aaaaggtatc
    21841 catttttttc gagcatccat ttatcaactt cctttctaag tgatttatat ttacttttat
    21901 attattttag cttacacacc ccctctattt agtatatatt tttaatatgt acacatatta
    21961 agtatataaa tttatttaat actaaataag attttttgat tactttgtgc taaaattagg
    22021 atgtaaattc gtatcattaa gttaattata aagtcatttt gaccttaagt caatgctttt
    22081 tatgtcattt tgaccttaaa tttgaaacta tttacatctt aaaaagtctt tttgacatta
    22141 attgaatgga gagtgtttat ggatacttta ggagaaagaa ttgtttattt gagaaaagca
    22201 aaaaacctta aacaatatga actagaagaa atgttgggct gtgacaactt aagtaaattt
    22261 gagagaaaca ttagaaaacc aaattatgaa atattaaaat ctatagctga gatatttaat
    22321 gtttcagtag actggctatt aaatggagat aatctatcac ataaatcaga tttaatttgc
    22381 gattcctcct caaactatcc acttaatagc ataaactcta atgaaataaa gcttttaaac
    22441 aattttagaa agttaaatga ttatgataaa gccaaaatag aaggtatgat tgaattaaaa
    22501 cttcatgaat atgaaaaaga gaaggattta ggaaaaattg agtataacaa aaataaagat
    22561 gagaaaatag ataaataatt tttatgttgc ttttgatacg attttacatc atttctttgt
    22621 tctaatattt ttatttcatt tattttcttt tttataattt tatgataaaa taattagtat
    22681 attttgcttt acttgaatgt aattatttat acaaaagtca aacataatat aaatgtagta
    22741 aatttttagt ttcaagtaat atctcgttat tataactaaa tatttattaa aattaggagg
    22801 ataaaatggg cttaagagac aaattcgcgc aatcatttgc tagatcaaaa actatgagtg
    22861 gccctgagaa aaaggctaat gaaataatgg gtaaattgct tcttaagaaa gctatattac
    22921 ctatcgtttt aatgttcgtg ataataatcg ctggagctat gcttaaaatc aattcttggg
    22981 ttacacttgg cataaattta gttattgctg ttggtgcttt cttctacata agaaattcta
    23041 gtaaaaagta tcagaacttt aaaccttatg ttggcaattt gattagttta gagaaaaaag
    23101 gtaaaaaaga gtacgttgct attataaaac aaggtaagtt accagttaag ttacaaatag
    23161 cttatggtgg tgaagacctt gaacatgtta agaaaaatca aatggttcaa ataagttata
    23221 atccagatgc taaaatagct attttggtta atagacaata atttaataaa aaaaaggagt
    23281 tgtcttaaaa ttgatttttt ctaatcaaat ttaagctcaa ctcctttttt aatttttata
    23341 tattattttt atatattatt tttattactt tttttaatta atatttttaa atatcaaatc
    23401 cttctcaata aaatagggta ctatctacaa tactacttta tcttttccta acaatatata
    23461 atctggtgct actctttcat gttatacacc gttttgtaac atacctttta taccagtaac
    23521 atcttcctta atttcctcta catctgtttt cattataccc atttgaacaa gtatattttt
    23581 gtttatttct tgttgttgtg tagataattc tataaaattt tctacagttt ttttatacat
    23641 gtctctatct tcttttttct cctgcatagt atttttaaat aatagagcac atagtatacc
    23701 tattgcccct agactactca attcggttat taatttatcc attatagcct cctattgtct
    23761 aaatttttta tacttatagc tttaattttt gttatattct tacatcatgc aatattatat
    23821 tttcaggatt atcaatttaa tcttctgtac tttaaattgt aggtgcaatt tatagattga
    23881 ataaataata aatatatata caatttctaa tataacaaaa aataagtaca aggcttactt
    23941 attaaagtta agaccttgta ctttacataa aaaaaataac taatacatag ttattctaaa
    24001 tttactattc aactggtatt tctaattctt tgcatctaat tctaacttgc tctctaatta
    24061 ctgctggtac ttcttctatt gtttttttgc ctcttaaaat taaagctaca tatacttcta
    24121 ccattccact ctcacctcca gattttctta cactaaaaga gcttatatta cttgcttcat
    24181 tgacagaact ttgatttaac aacatctcat atatttctgc atttgctata aaattatttg
    24241 ttatatcatc atcttgcttt acttgaccta tacttatgtc tgaaatgtct ttatactgca
    24301 tttctacttt tctaccttgt ttgatttgtt ctattttatt tttatcgaat ttaaacaatt
    24361 ttcacacctc cattttaagc ttgtggctcg ttgctttcag catcatatct aaaaatcata
    24421 gatggacgtt ttatagctgt ccatttatct cctttttcta ctatgatttt aggctgagca
    24481 ctttttatgt tggcttcttc taattcatag atttcttggt aacttgagtc tgattttttg
    24541 atttcaacta gtttcatgtc tttgaataag tcagatttat ttatttttac ttgaacttta
    24601 gttttattta ttaattgata tataggattg ttttccatca tgtcatcctt taatccctca
    24661 tttaatgtta ctattaaatc agtgttattt tcagtaatgt ttatgattga atatacttta
    24721 ttgtttatca ttaaaataga atcctttttt actttaagcc ctgtttctga tttaaatata
    24781 aacatacttg aatataaatc gcctgtagga ctactggctt taatcagtat cttattttct
    24841 cctaatacta ttttattttg tggtatctca aatataatgc tatttatttc caaattagtc
    24901 ttagtagata ttaattcatc atttataaac atttcaagtt tttctataac attattaggg
    24961 tcttgtacta caactctcac ttgagatatt gatttttcaa ctatttctat agatgcttta
    25021 cttgtatcta cttttgttat catgtatatt gtatcatctg aaagctctat atctaaaata
    25081 tcatttagat gttcaggaat tggtatttta gtaaattcat ataaatcagt aattgatata
    25141 gatattttat acatagattt atttttacca gttatccata gactattatc atttttaatt
    25201 actagtatgt ggtcatcatt atgtgactta atttctttaa cattagttaa tactttagta
    25261 aaagttctta ttatcttatc tttttcactt tctcctagtc caaataatcc atttgtattg
    25321 tacccttgag cgtacaactc tccctcatta gttaaaacaa gtgtcattga gttatatata
    25381 cttatatctt taacagaagg taatccagta accttttgta actctcttac atcattattg
    25441 tggccaactc ccaattggta ctcagtattc tttccatatg accatagagt attatctgtc
    25501 ttaataatat aggagtagtt atctccacaa gcaacttttt tgacatctga tatatttact
    25561 tcagtaagag ttaataattc tatatcttca agggtttgat taatttcttt atatgaatta
    25621 cttcctattc catataactt gccatcctta gcaacagcca atgaatgtgt ttttgatata
    25681 tcaatatcag atacctcaaa tggcaatatt attgaagtat acttaaaatt atctttaaat
    25741 atgtttttat aatttatata cttattattt gtttttatat acttatcatt aaacattact
    25801 agcttttcat ttttcttatt aaaaactatt ttatctgatg tgttatctgt tttaaaatat
    25861 gaatgtaggg aaccttcaag agcttcattt ttatcattat catatctatg gtgaatacct
    25921 aaatgattat atctattatc tcctgttgaa gaataaaatt ttccatatat atctttaata
    25981 aatatagtat tgtaactaga aaatacagta tcaacatctt tctttataga tactttataa
    26041 tatggaactg acatatccct ataagattca tcagatatac cataagtatc tctacctgat
    26101 gatatcaaat tgttattatt atctatataa agtgtattat tagctgttac aaaaacatct
    26161 ttaacatctt ccacactatt tgtattatta ttatttgcta tacttccata tccactaaga
    26221 cctccaacaa atagtttatt gtcatttgtt aaaatggctg aagtatatcc attaactact
    26281 attttttttg catttataat attattaatt actcgtatac cctttatatc attagtttct
    26341 gttgaaaaga ataccctctc ttttttccct gtagtataaa taacattgtc atttgttata
    26401 aaaaatgtag cttcacttcc tgctgttaca acagatttta cattctcaat atttattttt
    26461 gtaaatgtac ttatacttcc ttcagtaaac ccaaaatatc catttacaaa tccacataca
    26521 taacatgtat tatcattttt aacaattatt gatacatcat tacatatata cacatctcta
    26581 actccattta taggtatacg tgtaaatata ttcctacttg tagtatcacc caatcctaac
    26641 tgtccttttc cattattacc tgctccatat aaaagaccat cattagttaa taatagagat
    26701 gtgtttccat atacagctac atattttaca ttttcaacat ttattttagt aaatacattt
    26761 ctatttacat tatctcctat tcctaactga ccagaattat ttaaaccaac agcataacag
    26821 gtattatcat tttttatcgc aaatacatgt ttactattgt cagtaaatct atttacattt
    26881 atagatttta tattatcaat atttatttta gtaaatacct ttctatttat ctcatctccc
    26941 actcctaatt gacctacatc atttaaacca acactgtaaa gcatattatt attagttaat
    27001 aaatatgtag acttcgaatg gctatatatt tcttgtatat tagaagatat ttcactactg
    27061 ctattctttt tattgtaatt tatcttatta tttaaattta aactactatt aactgatata
    27121 ccatgcgtac ccttagagtt atatccacat ataaataagc tcttatcagt taatattgca
    27181 aatctagttt tatctctact taaatcataa ggaggtataa atatattttt tatatttttc
    27241 attacctttt tataattagt ggcattatat ccatcttgtg tatctgaaac atctagttct
    27301 tttgcacttt cagatatatt cccaaaacca tataacgtgt tagaagataa atacaataga
    27361 gctttatata aaaatatggc tttatcagag gtaataggac ctgaatttat attagatgct
    27421 gcaatattat tagatgattg attgttaaga taattccttc catattgatg tatataagat
    27481 gaacctccag aaataagtaa attatctgga tttacatttt ttaaattact tgttgattct
    27541 ccataataca aataggcaaa atttgtagaa tatgatgatt gtgtacacct tgtgggataa
    27601 tagttatata tgtaattact aatatatcca gcatgtgtaa ttccttgttg ttgaactcta
    27661 taagtagaat cacttggctt tgtccataaa gtaccatggt atccagttaa aaaagaacca
    27721 taatttgtac ataatatagc catatattca tatataataa tattattaat tttagtaata
    27781 tcatttgtac aagaatttgt actataactt gctcctgaag gatttacata aaaccagtta
    27841 tttattaatg ttaaatttat attgactcca tcattaggat taacacccaa taaatagttt
    27901 gtatttatac cagttgcata tacctttttt tcgtcagcca caataaatgt tgcattatat
    27961 gaactatatg catctgttac attgctaaca ccaatctcag tatattgact tgctgattta
    28021 ttactaagtc cattaacata acttgaactc tttccagaag tatatatttg cttattatta
    28081 gttacaatta atgaaaacca gtttgataaa tcagtattta taacaacttt ttttacatta
    28141 tctatagata ttttcttaaa tatatctgaa ttagaaggaa gaacacctgc tattgagtta
    28201 ctatttggcc cagaataata acaagtgtca tcatttttaa tgtagaatat tcctccagaa
    28261 atattttttg atgctactat agactttaca ttagagatac ttaattttgt caactcattt
    28321 aattgacttg gtaagtcaga acccattcct ttgtatctat tatttcctag accatataca
    28381 tctccattcc ctaaaataac cagagtacaa taaggactaa aaacgacatc tcttacagaa
    28441 tgtatatcta gtggaagttc aatatccttt atttccattt cttcttttaa taaagttaat
    28501 ttatcctcag atttaattaa atttatataa ttactataac tatatttttc actatccatt
    28561 ttcttaaatt ctacaatgtg catatcatca aaaaacgaac ctaattgtcc ataagtatta
    28621 tctcctgtac aatatgaatc attatttgaa tcaattagta tgctatgtga taaaccaatg
    28681 aaaatattct tagctacaat attttttaaa tctataaatg aattatctat attctcagag
    28741 taatttgcta tacctaactg atatatatca ttatttccag caaccttcaa aataccttta
    28801 ttatctataa gcatagtatt accattacca catgcaatag tttttatatt tacttcttct
    28861 atcttagtaa atagtgatga ttgaagtgca tttccaaaac atttttcctt tccacaacca
    28921 tatatatcat tattatacgt cattaacaca gtgtgttcag aaccacaagc tatagtctta
    28981 acatcattaa tagaaactaa gctaaataaa tctctattat tcttatctcc taaacctagt
    29041 tgaccttgat tattaaaacc agtagaataa catttattgt cattctttat tataaaagct
    29101 gatttattat atgagaatac agcctttaca ttatcaacat ctacttttat aaatgtattt
    29161 acatttgcag atgctccatt agttcctaga cctaattgac catacaaatt atttccagca
    29221 acatataaag ttccatcatt gtataaaaga tatgttgatt gaagtccaca tgcaatatcc
    29281 tttacgcctt ttatttctgg aaccttctca aatgtggaaa ctgtttttcc tactttttct
    29341 aatcccaatc ccatttgacc atctgtattt atacctgcga caagtaattc tccatctgaa
    29401 gtaagtataa ctgcatgaga ttctccacat gcaacttttt taatattagt agatatattt
    29461 ggtattttcg taaataattt tcttgttgta ttgtcttctc ccaatccaag ttgaaagtta
    29521 ctattatctc cacatccata caagatatta ttatttttta gaccaaatgt atagttacaa
    29581 catccagtaa aaaaattaat aaagtcataa ttatcatacc cttcatcaaa ttcatcaact
    29641 accatatttt tatcgccaaa gaaattacct ctttgaagta gtttagttct tttcattata
    29701 aaaacctcct aattatctta tttcatacga atatttattt aaagttatat ctgtctggcc
    29761 aattgaatat gccctattag attttgtttc aacaaagtta ttatccattt catgtatata
    29821 tctaactcta tttgcattaa atggtagaac cacattctta aatgtaacac taccaagttc
    29881 tccagttata cactttctat ttaaatctaa cttaaggcct tctatagcta ttatgttttt
    29941 agcattagtt aaggtatcat accaatatcc agcttcatct acatctattt ctgactctaa
    30001 ttctaagtat attaaaatat ctaatacttt ttcagataat ttattgtaac tattttttaa
    30061 tacagatagt tcagtttgta tttgacctcc tattacatca tcaatagata tatttttaat
    30121 tttttctact acctcattta tagctcctga taagttttta gcttctgtag ataagagttc
    30181 ttctccaatt tttactttta tttcttttat atttttatca accttatcat ctaaatcttg
    30241 aatatccttt tgagttacaa aaaccaacgt cgggtctact tctaatgtaa catttgaagt
    30301 attggacaat tgtaaaatca tttttacaac caaatcttta atactgccat cttcagcacg
    30361 tggcttatac gtctctggat acttacctat agctattata ttattctcat tatccagaac
    30421 agcagcttct cttatcataa atccaccaac tgttcctggt aaaatagtct ctataactat
    30481 ccaattagga tttttttcat caattcttag agaatttata tttccttccc aaactacatt
    30541 ctttaaagca gtttgttcct ctgttggctc ataatattct ccattactat ctccaacttg
    30601 aaacttggtt aatccaacaa gctctcctag tgcagttgca tttgctattt tttctctacc
    30661 aattttggtt aatattatat aaaatttttc ttccaattat accacctccg atttaggata
    30721 aactactaca ttttctacgc ctgtatcatt tgcaatagct atattaatct tacaattatt
    30781 ttcaatgcat ttaatgctta aaggataaac ctttatttct tctctactta acattccagc
    30841 tccacagttt acaacagcgc tacattttat aattggttca aagtatggat gaacttttac
    30901 ttcttcacta cataccatac ctccaccaca atagaccata cttttatcta gtattattgg
    30961 ttctaaatag tgtaataagt gagcaggttt tactctttca atcatatcgc tacaatctaa
    31021 aagagtttta tagtcacaat tatttgctat aaaactcaat acgaatgtaa attcatcact
    31081 ataaactttt atatctgttt ctgattttgt atatgcctca catatacttt ttataacttc
    31141 aatagtacta gtacctctgc ttctcatttt agcttttata ttgctacgtc ttgtgtcaaa
    31201 atcaagttct tttttttcaa tgcagagtat gtcttcccac atatctaatc cccatgttgc
    31261 agtgtcaaca aataattggt taaaggtatc atcaatatct tctttaagaa tatttaattc
    31321 tgtatcgtat gcaccttgta tctcctctac aatgtaattt ctatcaaatg atggtagttt
    31381 atcaattagc ttcattgatt ttccacctca ctaaaattaa cagttgttac actaggtatt
    31441 ttatcttcat taatagttat attatctgta cttccattta taagtaggtt acttaaatcg
    31501 tgtacaccag tagtatttat aagtattccc attacttttg tatagattat ctctcctcta
    31561 atatctctaa agtatgtatt tatactttct aggaaagatt cttttacatt gtctaatgta
    31621 tatccatctt ctaatttcat tactgcactt atatttattt ctattggtaa tggtgtcaca
    31681 actgttatag ttggtccaat aggcttctct tcatctatat gttgctgaca cctttcaatt
    31741 gtttctgtat caacagcttg attatttttc ccaaatatca agaccttaac tgttcccgga
    31801 ccatcccatc ttggataaac cttaacatta tagactccat ctacttccaa agcccattct
    31861 tcatagtgag ctttatttcc acttgtagct tgatttcttt ggattttata aaatctttct
    31921 tttagttctt catctgtctc tatatctgta ccaccttcaa aacttcttgt gttagtaatc
    31981 tttgttactc cagatatatt atcaactagt ttaaattcac aatttgtagg taaattatat
    32041 ttcttaccaa cttccagagc ttgaactggg ctattgtcac cttcttcact accaatagtt
    32101 acatctttta ttactacaaa tagtaaatct ctatatgata ttattgtgcc attatttatt
    32161 acagttcctt tctctccaat aaattcaact tctccatttg actctgtacc taactttcta
    32221 tatacaccaa attcattgac tcttttatcg agaaactggt tatatgtgtc ttgtataaaa
    32281 gccattttat gtatctttga aagttctaga tatatctttg aaagttctag attatttcca
    32341 gataccatgt tgtttagaaa agaaccttct cctttataaa tatcaagatt aatattttca
    32401 agagttctat tttttattac ttcatatgtc tggtcactat acatttattt ccacctcccc
    32461 atagatagtg gatactttta catttgcact caatacgtct ctgttaaagt tagcactttt
    32521 tacgtttact tctaatatat atggatttat tagaagggcc tcttttatga atctactagc
    32581 ttcactttct gtaagacctt ttgtatattt ttgtcctatt agttctgaaa gctctgtccc
    32641 atattctaaa gagtatatct catgttcata tctatttgtc tttatacact tgtatatcca
    32701 aacttttaag gcttcttttt tttcaattat tttaaagtca cctttttcta aaataggttc
    32761 atctttttca aaatcccatg ccacttcacg aaagattggc aattcttctg ttttaggtaa
    32821 gatataatcc tctgggacac ctataaaagg aaatattgta ctcattataa gctcaccaac
    32881 ttacttacaa cagcaaattt ttcgcctatt ctaaacatta ttaccatatc cccagattca
    32941 aaattatcta taaaaggatt ttttacttca tgctggtgtt cttgatttgt ttctgtgtca
    33001 aatgtttcta gctgtctatc aatcatccaa ctatctatca aaatatcttc tttttctaat
    33061 atgatgttat ttgtctctat ttttaaatct ggtaatttac ttttaatttt tccaataaaa
    33121 aaagaaggtt gattatgata ctttccttct tctcttatta ttcctataaa ttcatttatt
    33181 ggattagcca ttatatcacc atccttttat aatactctcc tagctgtatt aaaatctctt
    33241 ctactactta acttacttat tttaactaca tcaccttttt gtggagcatg taaaaattct
    33301 ccattaccta tatataatcc aacatggctg actggattat gaaaaaatac taaatctcct
    33361 gcttgaagat ttttttgttc tactttcttg ccttttttag attgttgatt tgacgttctt
    33421 ggcaaactaa cattaacttt tttaaaacaa tagaccatta aaccagaaca gtcaaaacta
    33481 cttggtccat ttccacccca tttataaggt ttacctagat gtttttttgc ttctgatatt
    33541 actattttag ctttatcaga tacattacca gaataaccac caataataat ttttcctttt
    33601 cttcttccaa atttactagc ttcttcaaca tttccaaata aaatatctat atggtatgtt
    33661 ccattctttt ctatagttat tgcaggtcct acgtcattta ctttatagac tccatcacga
    33721 ccagaaactc ctgtaattac ctgtatttca tctccatagt ttaataaagg atgtttattt
    33781 aaaaactctt ttgtataata agtttgttca tatttaccaa ccataggagc agcgcaagtt
    33841 tttttagatg ggtcaagttt tttctttcta caatctgtat ctccaccttc ttcttttcta
    33901 ggacagtaag ctgtaaattc tgctgtaaac tcttttcctc ctgcataatc ttctccccct
    33961 aagttacttt cttccttagg ttcatcctgt cctgctgact tttcatccat aagattttga
    34021 aaattaagtt caagctcaat ttgatattct ccattttgcc aagtatgttt gtctgtatct
    34081 atataaaata gtcctacaag ctttgtataa gaatctttaa cttttactcc tctaccagtt
    34141 atacaactta catctccata acctttaaga gaacagcttt tttctatccc attaaactcg
    34201 ctatcaatat ctacatcttg attttcttgt tgctgaatta ctttttgcat tattacattt
    34261 acttccttaa aaatttcatt atctattttt tcgctaatct tgcttccata ctggtctacc
    34321 actattactt tattttttac attttccatg ctctccgaaa aggtggtatt tataatatta
    34381 aatccctctt caaacataac atttaatgta acagttcctt tttcaataac attaaactta
    34441 tctaaattgg cctctatcat atactttttc tttgtctttt tacttgcttc tgtatatgca
    34501 ctcattattg tgtcataacc atttactcct ataaacatct ttgtatactt gacattggtc
    34561 tttgctattg ttccaactga aagcctattt tcagcaaata cttgctttgc tatgtcttca
    34621 actaacttat ctttaaaatt gtatgacact tcactttgtg taagtaaaaa tcccatatct
    34681 ttagatacaa aactaatttc attactgctt gaatctttag acctattaat tatcattcct
    34741 ctaaagagtt ctttctcatc tacatagaaa cagactgtac tagctattgg tatatctatt
    34801 tgttggaaat ttacatcaaa tgatgattgt attattgaaa actctagtgt ccttgatgga
    34861 gatttataat cacctgacca tgataccttg tctactatgt cagttatgtc atatatactt
    34921 ccgtttttta tgtgtaccca aatcttaata ataaaaaatc acctgccttt tcatttaatt
    34981 ctataagcag ttatttataa cttattatct ataatagtta ttgttttgga gttacttttg
    35041 gtatctttat tcttttatac tcttttaaat ctaatgtaaa atatacatct cgagtcccat
    35101 ctctttcttc ataactaaac ccttcaatta tgacttccat atttatattt gtttccgtaa
    35161 ttgtaaatct taatataaaa ccttccttca tccatttttc tatcttattt acacaatcat
    35221 atggtgatgg aaaacctgta tagtcacaga aagtatagtc tttatttgga aaaaaacttg
    35281 atattgaaat gcttttaaga gctacaccac caaaagttgc tatttcacct attttgagta
    35341 tactagaaga gtttacagca gcttttccat taatactaaa ggaagatgga aatactggaa
    35401 atctaaatct atcttcagct tgtctaagcc acatttccat tataagacac cccctaactg
    35461 tgccaattgg atacttgcaa ctaattttga tgttatcttt tctatatcag cttcttctct
    35521 aatcactatt gtatcagcta acttagctat gtttatattt ccaccatttt ttctgcttct
    35581 atattgattt gcttcttgtt tagttaaaac catttcacct tcatggagtc tggtttgata
    35641 gtcattataa ggaacatagt tcaatccaaa tgcattatta cctttcttac ctgaataagc
    35701 tttaccagaa tcaccagcct ttgttccagc atatggatta tctttgtaat tttttttact
    35761 cttttccact agatttaaaa ctgttcctgt gatgcttcca ttttttatct tattaatcat
    35821 agtttgccac cacttgcata tatctttaac tattttacat actttatcta atatgttaaa
    35881 aaaagctccc aatattggct ctataatttt ccatccagtt tccaacagag gtcctaaggt
    35941 ctcccataca gttttccaaa taacacccag tgtctctata aaattgttta tttgaggtgc
    36001 atattcacct aaaaaagtaa aaattcttgt gataatagga ctaacagctt caactacagg
    36061 tccgattagt tggaatgctg tagttactat tgtaccaaat atacttatta atccttgtgc
    36121 aattggtgat ttattgttta tactatctag taaattattt actaagttta ctactggaag
    36181 taatgaatct attaatgctg taaaatcgat attttgtaat agtgtacttc ctgcgttaac
    36241 aattgctttt ggtgcattcc ctatcattgt tgctgcatga ttttcaaaac gttcttgctt
    36301 attttcaacc atcattttac gcttttcagc ctcattagaa attcgatatt gagtagaatc
    36361 agaaaactct tttccatttt ttacacttct agattgcatc tggtcatatt tgttgccaat
    36421 aattatctta ccattcatta cattgcctat tttaccagcc attttttcag ataagccagc
    36481 taaattgcct aatccacttt ctataaaagt ttttattttc tttagtcctt gacctaaaat
    36541 atcatcaaaa ggtttaacaa tactcttcaa gccattgtta atgcttgttt gagctcctga
    36601 tattatacct ggtattgtat tactcatttc tttagctaac cccatctgct ttacacttat
    36661 gccttccaat gcttcatcaa aagttttata attttctcct accagagtat taagagattc
    36721 catgtttcct tttgctgcac ttaagaaagc tgctgataca tcttgttcac tacttgtatt
    36781 catatttaaa gctctaacat ctaccatagc ttgagttata tctttttctt ttttgccacc
    36841 agtaatatta ctaatcattt tagctttagt tcccattgca acaacatctt cagggtcaaa
    36901 aggcgtatca tttgccattc ttactaaact gccataataa tcatcaacat ctatttgatt
    36961 aacttttcca gtatttcttt tcattacact ttctagaaca actttctgat tttgttcctg
    37021 accaagtaaa tcaacaccct ttttcacagc gacacctata gtagcaccat ttgtcaaatc
    37081 agatatcttc ccttttatcg aaccaagtat tccacttgcc atatccttta cagctattgc
    37141 accactccat accttacctg caaataatct caatttggga aatactttac ttataatgcc
    37201 acttgccata tcttttatag ctattacacc actccaaaaa gtatttttaa acaacattaa
    37261 cttaggcaaa attctaccca tagcactact caccatatct ttaagattaa tacttccttg
    37321 ataaggacgt ttctctactt gttttaattt tcccaagata ctacttataa ctctcttagt
    37381 catatctttt gcttttatta cgatattcca aaccttgcca ccaatctttt ttaaatttcc
    37441 aagtaattta tttttagttt tttctacttc atcactttta gctttaaata ttaatataat
    37501 cataatattt gaattaaact catttttctt ttgaatcaac ttattaaaat aatcaataat
    37561 catagctata gttattgcta gtatcataat acttccattt aaacttccaa taactcctga
    37621 aacagcattt atgctagaac ttaattttgt catagttgaa cttacactac tagcagtagt
    37681 ttgaactttt cttaacgagg aatttaaact gtttactcta ttacttgcac ttccaataga
    37741 attttttatg ctactagcca ttacattagt ggaaagtgaa acagccacag ttgctctcct
    37801 aaaattatca gttactgata taatttgatt catttttggt gtgtaattat ctgtaaggta
    37861 catatttata ccttcttctc tcacatttcc cattacatac cacctcctgt caaaggacac
    37921 actccatatc catgtttcat tttttcaact tcttcctcaa tttctaaggc gaaaaaagct
    37981 tcaataagct ttaattcgcc tttatccatt gcataaaaaa gggacggtct tatacctttt
    38041 ttcttccaat aatagtacat tattgtagtc ctggtatccg tccctattag ttttttacct
    38101 cttctatcac tgcattttta ccataaccca taacatcttg aagtattcta tataagttgg
    38161 taatttcacc tggtaataat aattttcttg ctaattcttt tggtgttgga gccttaaatt
    38221 tatccattag ctccttattt ttaaataaaa gctttccatc caaatcacaa acaccttcta
    38281 taattgtaag catctgcatc tccggtaagt ctatatccgt tttcatattt tcatcaattt
    38341 taagacaagt attttgtatt tcttcatctt tacttattgt taaagctcta cacattactt
    38401 taaattcctg cccaaatata gttgataatc tcttaagttc aactatagta ctcggtcttt
    38461 ctaagttttc tgtatctgaa tttaaaagta aatctactat gtttatattt tttgataatc
    38521 cattttcact cattattatt tgctccttta tcaatcaaat tcaatcaact aactttttta
    38581 cttattaact atctgaattt attaagtata tatttactaa atatcagtat aaaaccaaat
    38641 ataaaactaa atataaaact aaattatatc aagaaaatca tactcagtaa atgtgaaagg
    38701 tgcttctatc tctcctttta cgccaacctc ccaatcagct aaagttaaat catcaaatgc
    38761 tatattcttt actgctattc tttctgctcc ataagaatct gggtcattta atttagatat
    38821 agcaacaaac ctaggttcag aacctctctt tatcttttct ccaattaact tgtgcattct
    38881 tgaactaacg tggtatagag ttattgagcc ttttccttta tatcctatat actttgtatc
    38941 agtacccatt tgacctgcta ttataatatc ttcttttgta aattccatct ttgcttgaaa
    39001 tttctttact tctgctactt tgtttccatc aagccaaagt tctccccaag taccactcat
    39061 tacatttcta gcttccatat ttgccatatt aataatcctc ctatatttct attgataaat
    39121 ctatatcttc catagcatca agtactttta tttttgcttt taaaaatact ttagaacctg
    39181 tgttagcttc ttttatttct tgtaatgtca tataagataa atctactcct tttgatttta
    39241 aatacgattt ttgtgcttca aaatctattt caacagtaga atcagattct ataagtgctg
    39301 atttttctaa ttcttctaaa taacttttta tagctactat caataaacat ttgttgtcat
    39361 aactgttagt aacctttcct atatagtcat ctattatcac ctttcttatg tcactatgta
    39421 taatatctaa agtgtcaact atttttattt tctggaacat ttctcctttt tctgctgtta
    39481 attcagttaa agaatttact cctctagcaa ttcttatagc tcctgcttct ttaataagta
    39541 taagctctcc tttattaacc tttgattctg catcaacttt cgtcatctta ggtatatcga
    39601 ctacatcact aagtttagta taagttactg attgacttaa aggtgtacct gctataagtc
    39661 cagccaccct acttgtaaac tcatcaacac tgtatttctt ttctccaact aacacatctt
    39721 ctgtagtaaa attaattatc ccttcatgat ttcctacaac ttttcctaat acagctttaa
    39781 ccttaacctt atctatatct ctaagtttaa ttatccaatt ttttatagca gtcttatcag
    39841 cttctactgc ttttggcata catagataat taaattcctt agtctctaaa aaatctaatg
    39901 cagtttgaat atctgcttct ccttctatta cataaactaa taacttattt ggagtgttaa
    39961 catttcccat caaagctaaa tttatatatt ctttattttc agcagataaa tcaactggta
    40021 tatcctcttt ttcatgtatt tcattaagac ctagtgcctt agcatcttta agtaccattg
    40081 caattattcc tctagctgaa cgttctttaa cagttgtagc tagctcctta aatgatatgt
    40141 tgatacttgg taatcctata gccatactat cactctccta aatttaaatt gatttcttcc
    40201 atattttcat atactacatc ttcttcatat acactatcca gatagtttag tgtaaatgta
    40261 aagttcaata cataaattga ctcttctttt ttaatacttt gttctagctt tgttatattt
    40321 aattttctgt ctgttacctt tatatttctg ttgaataact tatttaattc atctgaaact
    40381 tcatacattc taatactctt tgactgtggt tttggtaagt attttataga gataacaata
    40441 tctttgttat tcgtatttaa cattacaggt gtacaaataa ctgatagtat acttacaaaa
    40501 aaacaagacc cttcagagcc ttgcacactt tcatcatcaa taaaaatact ttcagtaaag
    40561 ttttttttga gaatctcaat aattgtttct aatatttcct tgtatttaag caaataatca
    40621 ccacactatc actaaatatt cttgcttaat ctgataatct tactataaat gatataagtc
    40681 atttttaaat atatatctca tttattcctg tcaagtatct tctatatttt taggtaatat
    40741 tattcttttc aatctatcac ctccttcaat atggatttct ttcacaataa cattatctca
    40801 catattttat tgcctattgt tgtaatggtg tatataaagt gttgtaaaat tgtcctattt
    40861 tttataatat ctcactcaat ttaaatatca tctttttctt taaattgtag caagatgttc
    40921 tatctaagtg tagtttcata gaaatatatg tcatattgtt ttttgtctta ctattataaa
    40981 aaagattaaa aaattccatt tctatatcat ttagacacgt tagagcattt tctatcttct
    41041 ctttttctat ttctatatct tctttttcca tttttaattt tcttaatctt tcctctcttt
    41101 ttaacacctc attttccaca gaagagctta tgttatatgt gttactagtc ttttctgtat
    41161 ataccattgc tccacatcca gagtattcat tctcacatct ttttatgtcc aagttaatat
    41221 tctttatctt tatatccaaa tacttataat tatgtaatct tttatctgtt tctttaaata
    41281 atatatcttt tttgttttcc atagtacttc ccctttttta tatacttatt attagcttca
    41341 aatttacaat aatctcttta gtgcacagtt ttttactaat ctcacaacct tcaagaacat
    41401 attgttctat aactgtataa aaaaaacttc ttctatattt tgttctaaaa tactagaaat
    41461 cttcttagcc ataagaagtc caggattttt tatgcctctt tctatttgag atatataatc
    41521 atttgtaatt ccagcctttc tggcaagttg aatttgtgtc atacctttgc attttctata
    41581 atatttcaag ttatttttaa acattgtttt atacctccat tactattaag aatattttgt
    41641 tcttcctcac ttagattata tagaattatt tgttctttat caatagattt tagaaaaaaa
    41701 tattctttta tattttatta gttttatttt ttagaacaat ttgttataat ctatacataa
    41761 ggtggtgtta taatgtttgc caaaagatta agagaactta gaaaggaatt tggattgact
    41821 caaagagaac ttggagaaaa agtaggcgtt tcccaaagag tcttagggta ctatgaaaca
    41881 gaaaacagat ttcctgatga acacatttta aataaattgg ctgatgtatt taatgtatca
    41941 gttgattacc ttcttggaag aaccttagtt aaggaaaata ttgatacagt agctgcacat
    42001 agaaaaaatc cacatgaaga gttacctgaa gaagcacaag aacaacttaa tgattatata
    42061 gaatttttac taaataaata taaaaaaaaa taaaccatat gatgagcagt ctatttttct
    42121 gctcttttaa tataattcaa aggcaaacat acattctatt ttagggggat ttttatgaat
    42181 aatttggata agctttttga attagcttct caagaagaga taataattca ttataccact
    42241 tatattgcag gtgatttaga aggactatat ataaacaaac atggtattaa aattatatca
    42301 ttactcagta atttaaaaca aaactcaaaa aaattgacat ccatcttagc tgaagaactt
    42361 ggacatcatt tcactagcct tggatactat gtatcctctt ataacgatta ttatacaaaa
    42421 attattatag ataagtgcga aaataaagcc ttaaaatggg cttgtgagtt cttaattact
    42481 gaagaagata taataaacat aattaactct ggcatcactt gcgtttatga aatggcagac
    42541 atacttaatg tggatattac tttctttcaa aaaagattag aatttctatc attaaaaaaa
    42601 cagtctttac aacttggaaa taataaatat ttaatattaa ctaatttgcc gtatttctac
    42661 atatttgatc caatttcata ataaaaatag tagtaatttt aactggctta acagtaaaat
    42721 ctatatattt attttaacaa attttggttt ctataaattc aatattaata tataataatg
    42781 atatcatatt atttaaaatt ctaaaaacaa atatatgctt ttgttaagaa aggttgtttg
    42841 atgaatgtat aaagaaaagt tgtttgataa ttattttaag ttcttagcac tattattttg
    42901 gccaattatg tggtataagt ggatagtaat ttcaaatggt actcttgaaa atatgttatt
    42961 taccatatat gcaatcgtcg caattgtttt catcatttta tattcggtgt ttatgataaa
    43021 atataaagac attacacaaa tagatttctt ttacaggata agtactctac ttgcttttat
    43081 atttacactt tttagctttt taatataccc aaagagttta tttttcttgt atttaaagat
    43141 tatttttact ggaatatacc tttattattc aatagtaaaa actcttaaat ttaaagatga
    43201 cgaaggtgta gtgggtatta tgagctcact tttattaatt gtaataactt tgttctacta
    43261 aatttaattc tatttgactt aatatggctt taaatattag acatctacat tattttctga
    43321 tattatttaa gatggtagtc ttatattaat aatgaaatac actatgaagg agttaactat
    43381 tatggaaaaa aaagttttag caacagttgg agaaaaagag ataactaata ttgatattga
    43441 aaatgcatta aaatcattag acccttatca agctatgcaa tttaaaactg aagaaggaaa
    43501 aaaacactta ttaaatgatt tagtgaatca agaattattc ttcttagatg ctaaagaaga
    43561 aaaattagat gaagaagaaa tatttaaatt agaaatgaaa aagatagaag aaaatgtatt
    43621 aaagcaattt gctataaata aagttttatc tagtgttaat gtaacagaag atgaaaaagt
    43681 aaaattcttt gaagctaata agagctcttt ctctaaacca gaaagtgcaa ctgctaaaca
    43741 tatattagta gatagtgatg aaaaagctaa agaaatactt gctcaaataa aatcagaaga
    43801 aatatctttt gaagatgcag ctcttaaaca ttcttcttgc ccatctaaag atatgggtgg
    43861 tgatttagga acattcggta gaggacaaat ggttcctgaa tttgaagaag ctgtgttctc
    43921 tatggctaaa ggtgaagtaa gtgaaccagt taaaactcaa tttggatacc atataataaa
    43981 attagaagac cttcaagaaa gtacagagtc tacatttgat gaagttaagg ctgaagttga
    44041 aaaaagttta ttatatcaaa aacaaaatga agtttatgga aataagataa atgctcttaa
    44101 tgctaagtac ggaaaccttg taaaatacaa cgattaatca taaggtcata tataaaaaag
    44161 ctgtcttttc acaatattta ttagaaaaga cagcttttta tattaaagtt taaatattca
    44221 gtttcatatt atcatttttt tattgtaaag aactcagctt aaaagtttaa ataagatttt
    44281 taattatcat tagctaaatt tttatatcca cgtattatct cataacagta acctattaca
    44341 tctcttcttt ttattatccc aataaatgtg tcttggtcat ctataacagg aatgaaattt
    44401 tgatttaaag attttataac taaatcttca atatctgcgt tgatggaaac aggagaatta
    44461 tccatttttc tatttatatc tgtcactgga acatcttcca atccctttaa gtccagattt
    44521 aaatcatttt ttaatgtcca taaaaaatca ccttctgtta tagttccaac atatttacca
    44581 tccttactta ttattggaat tgcagagtat ttgtgatatt ccattttttc tagggcttgc
    44641 cttatagtgt agtcttcata tatatatgct acttcacttt ttggtgttag aaagaataat
    44701 atgttcatta cactacccac cgttactgaa aacttataaa tattactcaa tatttataat
    44761 gttacttttt tgcagtaact ttctcctttc ttattttcta agtattctta atactatacg
    44821 ctgtaacaag cgtttttcct ttgctcattt taatcttatt atgctttatt aatattttta
    44881 tatggtctat aagtatcact tattctcttt ttagaaaatt tactaaaaat taattgactt
    44941 aaacttagcc ataataattt tactctacac tattaatttt aacatattta tctcattatt
    45001 aatgatttta ttttaataat tttaatttat tttgctatta attttattta caaaaactga
    45061 aaaaaccgct aaatgattag cggcttatct ctcatattac tagaacacta atatatatga
    45121 atttttaatt ataatctaac tacgttagca gcttgaggac ctttagctcc atctactact
    45181 tcgaactcaa cgctttgtcc ttcttctaat gttttgtatc catctccagt tatagctgag
    45241 aaatgtacga aaacatctcc ttcaccttct acagatatga atccaaatcc tttttcgttg
    45301 ttaaaccatt taactacacc agttttcatt aataaatcct cctaaaaaaa cacaaatatt
    45361 tagctactct tttctgtaac cttattacta ctctatcata tatagctatg tttgtcaatt
    45421 attattattt ttatacatta ataatcaatt tttttacttt ataattttaa atgattatta
    45481 tcttttacac tttatttttc tttataattt tttaataatt tatttttatt atatggaatc
    45541 ttatggactt atcactccag cctaaatccc atggcaccaa cattctatca gtattatggc
    45601 aagttaccaa aggatatcct cttgagtcta atcctgtcac tgtcgaaaca tgtgttattc
    45661 tgcctttctt ctcataacca acaaaatccc ctggacgtaa attataagct tctttgtata
    45721 cttcttcata ggaaccttta gcaattaatg aacctcttcc actatacagt gcataatttt
    45781 taaaagcttg tgcatttacc catgcttttg tacctgctct ctcgctataa ttccaaattg
    45841 agttcttttt gaaccttcca ctttcaaaca ttatctgtga tgcaaagttt gcacaatctc
    45901 caccttctgg attataatcc ctatagtttg gattaaattt cataccatgt tcttcatcag
    45961 ctgcggctcc acagtattta tgtgcataat ctatagcttt tttttgttca tctgtaagct
    46021 gtaactctac accatcttgt tgaccaatat aatttcttat atcatcagat tttatatttt
    46081 ctaaatttaa agagtctgca aaagggtctg tataccactc tttagttatg acatattgat
    46141 tatctataat ttttacattt agataatgat atgtacctat tctaaaggca ttttctttgt
    46201 ccttttgatt ttcatatgaa tacttatatt cagtggatac tgaacagatt ataccataga
    46261 ggtctttttc tttttccttt atttttttaa tcttaaccct tgtctttatg tctttaaatt
    46321 ttacaccttg tttactagac cagttttcta aatatttcat cttttttact tcattttcat
    46381 aagcccacag accaaatttt ttatccgttt cataaagacc ttttaaaata ttttcatttt
    46441 tctctaatat tgccttattt ctgtagtcaa ataagttttc aagcaatagt ttatattggt
    46501 cttttacatc atcaccttca acatttgcag attccatgac tttttcttcc atatttttca
    46561 tacttaaatc attgattaaa aatacacctg ctgtagtagc taaagacaaa aatacaaatg
    46621 ccattatacc tttgatgtac ttattcttat ttttcagtat tttcaaagct acacctccca
    46681 aatagtacac cttacaaatc aaattacaaa gaatattctg tcacatatag taattttcat
    46741 atttaataat tctctatttt attatgtcca atattaaaaa ttaattgtat caatacactg
    46801 ttttttttac aattttttat tttataatct acttttttct tttttttata gtaatatata
    46861 tgtatataaa tattttggta tcattataat taatacatac taatggaggg ttttttatgc
    46921 aaaaaaaagt cgcagcaatt aatgacttat ctggaatagg aaaatgctca ttatcggttg
    46981 ctatacctat actttcagca ttaaaggttc aatgttgtcc atttccaacg gccatacttt
    47041 caagtcaaac tggttatcct gaatttactt tcttagactt tactgatgaa atggtaaaat
    47101 attcaaatgt ttggaaaaat ttaaaagtca attttgatag tatatatagt ggttttttgg
    47161 gttcaaagca tcaaattgag atagtggcta attttataaa cgattatccc aatgctttta
    47221 tcgtagttga ccctgtgatg ggtgataatg gagttatgta tccaatattc acagaagaaa
    47281 tgagacagga aattaaagaa ttagttaaac attcagattt aactactcct aatttaacag
    47341 aagcttgttt cttaactgga aatgattata ccaaaagcga ttataataga gatgagctta
    47401 tatatattgc aaaatctgta tctgatttgg gacctagcaa agtcgttatt actggtatat
    47461 tagaagatga taatatatta aatttggctt acaatagaga taatgaccat gtattcttta
    47521 catcagtcaa atataataat tgttcttaca gtggaactgg agatatattc acatctatac
    47581 tttgtggtat gttagtaaat aaacatgatt tgggagtagc ggttaatact gcaacagatt
    47641 ttatatataa aactataaat tacacatctc aatttgatac tgatagaaat gatggagtta
    47701 tgtttgaaaa ctttttatca gatttaacca atatataaaa tcaaaaaaac tatccatttt
    47761 ataaatacct ataaatcata aaatttaggt atttacaaaa tggatattat ttactaaact
    47821 attggtattt caattgttac catagcacca ccagttttca cagaattttc aatacataaa
    47881 gtcccattat gtttttgtac aatattattt acaatataga gtcccattcc ataatgagat
    47941 ttagaatttc tactcaaatc tcctgtataa aactgttctg tagcttttga caaatctgct
    48001 ttagaaaaac cacttccaca atctgtaact acaaatttta agtatttatt atgtactgat
    48061 acacttatgt atagtttact ctggcttggt gaataatcta tagcatttga aattatattc
    48121 ataatagctc tgaataacag ttctctatct atagttatat ttttaggcaa attatcttgt
    48181 ttataaaact ccacatctaa gtttttagta ctagctaatg cttctatttg cactaaaaca
    48241 tcttttataa actcactcat actgattgct tctttattta atatatagcc attctctgtt
    48301 tttgatatat ctattaaagt attaatatat ttttctattt gagtgacacc ctttgagata
    48361 tattccatgt attctaataa ctcaggattt tcatttattt caattaataa gtcagtattt
    48421 ccatgtataa ttgttagtgg tgtttttata tcatgtgcca gtgcagatat ctgttccttt
    48481 ctattttctt ctagcatcca ttgtttttct aaagaatctt ttaacgccaa cttcatttta
    48541 tccatagaaa aaaggacatt attaatttca taaattttac tagattctac aacaaaatct
    48601 aaatcctgtt gttctatttt ttctgtagta ttttttaaaa gctccatttc aatattaaat
    48661 ttcttgccaa atacttttga taatataaca atttcaataa aaaatattat actaaaaata
    48721 atcataccca atgtctctgg ttttggtaaa tatgctctta aaattggaga actatactct
    48781 gatactattt tgtattttat tataaaaact tcatctttct taaaaaactt tatataactt
    48841 tctgaatatg catgcctttc ttcaatatct ctcattaaat tccatacttc ttttgattct
    48901 tttttattaa aggtccctga aattaaattc ccatccaaag tataaacccc atactcatat
    48961 atacttggaa ttatatcttc agttactttt tcacttgaaa taatctgttc tttatattta
    49021 ttaaattgtt tttctgcata attagctggt aaaattacac ctgatgataa taatacagaa
    49081 aatgataaca ttaaaaggag tacaattgaa attgtcataa taaagaataa agataaatat
    49141 tttataaaaa tagttcttaa cttttcaact tttttgttgt tagatttttt acctccaagc
    49201 atttgtaccc tgtcctccaa tagtttaatt aattcataat taatacccaa ccagtttttt
    49261 atttgattat tttatatctt tttattgcta agttatattt taacataata atataaataa
    49321 acagtcaatt tttactctat tcttctgatt ttttaccttc ccatttagaa aaccaaatac
    49381 ataaaattac aaatgctaaa attgttacaa aaccacaaat taaacctgtt gattgatatg
    49441 cttttattga ttcaaccttt atatattcaa ccgttttaga acttgaaaaa gacgaccaaa
    49501 tagttataaa tctaacaccc catgcacaag gaaaatactg ccaaatacca gaacccaatc
    49561 cagttaataa taatgctgaa agtaacattt caactatacc tactccaatt gatgttcctt
    49621 ttccgaacct taaacttaag aataaatgta atatgtattc aaataaatta cacccaatta
    49681 aaattagaat tgaaatcata taaaagcttg atgtaaagta agccttagat ataccaaatt
    49741 taaaacctaa tacagacact aatgttgcta caaaaccaag acatactaag attatatatt
    49801 tacttataag agtaagatat tttggattag atgttgttaa catatgttta taattccctg
    49861 cataatattc ttgttcaaca aacattgaac acacaacact tgacaataaa ggaaaagcta
    49921 ttgctataac ttgtaaatat gctactatct ttagtatatt atcagctcct gaaaccttat
    49981 aataccataa aaacaatccc atccccatta aagcaatgca aatgtgcatt agtattataa
    50041 aatttctctt taattttatt aaatcagaac aaaatattct tattaactgt ctcatattac
    50101 ttcacctctc tattattgaa ccaaaccctt gtagctaaag caaataatac aaataaaaca
    50161 atagatatta atactcctgg caaaataaca gcattattta aaaattcact tccctctggt
    50221 acaggaagac catttggcag aatatgcaat acaacagcca ttaatcttga aggaatcgaa
    50281 tatggaaaca tataccacat ttctgtagtt gagaaaacag caactccaac aatagtaaag
    50341 aacatatttg ttagaactgt aacaaacata ccaaattttg aagctaaaaa catacaaaga
    50401 ggaatctgcc acataaatag taaaataatt aatatacttg caatgatatt ttgacctatt
    50461 gaaatagttt ctttatagat tatcccaaca aaaactacac ctattgcaga aataattgat
    50521 gctataaaac aacaaataat acagtaaatc atttttccag tccaaacgtc tttcatttca
    50581 attggcaatg gtaaaatacc acgatattta cttttttcat cttttaatac tattaaagaa
    50641 gatattaatg ttaatgctcc tggaagaaat gtcgtatacc accagttgaa agcagcattt
    50701 tgccctccac ctagtccaca caaaagtata caaaacactg gaactatcca tatcaacttc
    50761 attccaaaag ttcctttcat cttttgaaat tccactctaa taaatctttc catattactg
    50821 ccctctcttt ctattttcag ctacaacttt cataaaaagt tcttctaagt tttgttcttt
    50881 tgatacttct ccttgataac ccattactcc attagaaatt attcctattt catctacaac
    50941 ttgttcaact tcagacaaga tatggcttga taaaataact gtaattcctt gttttggaaa
    51001 agaacgaatc aattctctaa gttcttcaat accaataggg tcaagaccat ttgtaggctc
    51061 atctaagatt aaaagttttg ggtgatttaa taatgcaata gcaataccaa ggcgttgctt
    51121 catgcctaga gagaattgac ctgaacgctt tttaaaggta tctcttaaat ctacagtctc
    51181 taaaacttct tcaatgcgag agtcaggaag accaagtaaa gtagtatgga cttttaaatt
    51241 ttctcgtgct gttaaattct catatatagc aggagactca ataagagaac caatatttga
    51301 taaatccttt ctagtccatc tatgtccctc aaacattatt tttcctgaag ttggatttaa
    51361 aatcccagtt atcattttta ataaagtaga tttcccagct ccatttggtc ctaataatcc
    51421 atatatagaa ttagatttaa ttgctagtga aatgttatca actgccatct gctccttaaa
    51481 ttttttagaa actcctttta cctgcaaaat ataattactc ataattttca tcctttcttt
    51541 tgtcaaactt atttacaaga atcattctaa atcataaata taaggatttt ataagaatta
    51601 aaaaacaaaa aaagatgtgt taaaaacaca tcttttttta tcttaattct attaattttc
    51661 cattgtagta tatctctact tcttcaatcc aaatgctatt atcttcttct tggatgacat
    51721 ttttaataat attatttata gtatatatta tattttgttc attcaaataa tcatctttcc
    51781 aagaaactct acttttttta tctggttcta tcaagtttat tttaacaaga ttatcttttt
    51841 ccttaacttc tacttccatg tctaaaccat taaaatactc atttgataat gtatctaaga
    51901 ttaatcgcag tttatcctta agtgaacttt cttcatcaat ctgtaagtac tttactattt
    51961 tctcatcctt tgaaattatc tctataggta ttttagtagt ttttttagaa ttaatcattt
    52021 tactagttgt ttcttctttt gcatcttcat ccttctttac aactgctgat tctttagaat
    52081 caactagctc aactgcactg atgctataat ccatacatgc cgtactcaat aaagtagtag
    52141 caattattaa aaaacttact gctattttat tcataagtat ccctctccta attctctttc
    52201 gatacttatt ataccatagt atagattata tttttatact tttaaatcaa tttataaatt
    52261 attatagtaa attatttaca attctaagct atttgaattt atttttatag tatattcttt
    52321 ctctaaattc gacagatttt tattcaaaag cccttttatt tccctcgtat ttctatactt
    52381 gttgctatgt tcttcattat gttcataatc atatgaatca ttgtcatatt cttcatcatt
    52441 attaaattct tcaattgctt cttttgactt tatatcacaa ttaaatttat acttatttac
    52501 tggtatatca agtcttacct tagaatttgg aacttctatg tccaggaact tagcaattgg
    52561 catatcagag tacaagtaaa attcactttc ataatttgaa tttctaccta ttttctcttt
    52621 tatatttaca ttttcaggta tatactcttc tatattattg ataaatacat ctccattctc
    52681 tgaagatata tccaatgact ctgattctat gtttacattt ttaacgccta aaattgactt
    52741 tgttgataga tgaagattgc tattagatat taagtttaag ttttctaatc tatttacttt
    52801 attttctgtt atagctctgc taaaacctcc agaagaagtt ttatatgtta tattatttga
    52861 atctacatca tcagatataa ataagtacga acttatactt gatgcattta tatctacatt
    52921 atttggtaca tatattctaa tttctctata atcacgtgaa aacatactat ttatagatgt
    52981 atttaataag tggtcgaaac ttctaatctt tttaatttta ttttcagatt ttctttcgcc
    53041 ttttacaact aaagtcttat cttgtagggt tacactgtat ttgtaaaatt cattattccc
    53101 tcttgttgtc acacgcacat cttcatttga actttttctt atcataacat ttatattgtc
    53161 aacagctata tctaacttgt caatatttac tttttcttga taaagtttgt tttctttgtt
    53221 taattcagct tccttttcta aaccaaagtt tattaggctt ggcataacta aaatccctga
    53281 ccatgttgtc cctattatac ctattaccaa taaaactgca gcaaatatag caagtttttt
    53341 attcatgttt atcttctcct ttcttatttt ctatatcttc aaggtcctta tatatcgcct
    53401 caaaatttat actatcatca ttatattcat cagtttcttt tatgctttct tcttctctat
    53461 tgtagtaatc attattatat gaattttcat taatgtcttt attcaaatct tcatcattta
    53521 aagtagcttt ttttcttttt tccatctttt catttgcctt tatataaata ttttttctct
    53581 ttatccaatg tatataatta tttagtaatt gtttacctag ttttatggca aataataaaa
    53641 tttgccatgc aagtatctca agccctacaa atgctatggt tgcgaaaata caaaacatca
    53701 taacatctgg aaccattgct ataaatttaa tcacaaatgg aattaatata acaaaagcaa
    53761 ttaatgagca tactaatgca atagtagcag atacaatagc acatacaaac gcaaatgctg
    53821 gaacaattag aaataaagat aacactacta ataacccctt tataacttgt ctggataatc
    53881 ctcctacacc ttcttctata cttggtgtaa gtttatcatt tatattttct tttgatttat
    53941 tgtacttttc cttagcttca tctttcaaga tagaataatc cttttttaca tttgatttaa
    54001 atctactaaa tttaccattt aatatgtctg tattcattat ttttccatct atattttctt
    54061 ttgatttact atacttttct tttgcttcat cttttaagat agagtaacct tttttcatat
    54121 ctgatttaaa tttactaaac ttatcattca aaacatctgt atttattatt ttttcctctt
    54181 caatattttt ttctttagtt tgtaagataa gttcttttgc tatagatttt ggtgagccaa
    54241 gtgatgctat tatctccata tcactctttc cctctataag accatctacg aaatactctt
    54301 cataatctct caatatatca ttaacttcgc tctcagaaaa atcttttttt agataatcct
    54361 ttaaaatttc aagaaactca gttttattca agttcattac ctccctcatc ttcacttatt
    54421 aaaatctcaa cagcctttac aaattctctc cactcttcca tcagattgga taaattctct
    54481 tttcctagtg aagttattct atagtatttt ctagcaggac cttcattaga ttctagtata
    54541 tatgtttcga aatacaaatc ttttgtaagt cttcttagaa taggatatat tgttccttca
    54601 tttacatcta ttactttaga gatgttatgt actatctcat atccatacat atctttctta
    54661 gatatgagag caagtacaca aatttctaaa acaccctttc taaattgtgt gttcatatac
    54721 tccatccttt ctttaaatac acagtattgt gttttacaag gtactatgtt aaaacttctt
    54781 atatcctcat aataacacag tactatgttc tgcacaatag ttatttttaa atattcttgt
    54841 tgattaaatc cttctataaa tgtataatac tctaatcaga tatattttat gaaagtggtg
    54901 ataaattggc taaaatgaaa gatgataaaa caatattaat cctaactgct caatttggtg
    54961 ctggacatat aagtgctgca aaagcagtca aagaatgtat tattgaaaaa tatagtaact
    55021 ataatgttgt tatacaaaac tttataaatg caagtattcc catgatgaat aagcctatgg
    55081 taaaacttta tgaaaacaat acaaaatata ctcctggatt atataattac tattattact
    55141 ttaagaaatc gtttgattca agacatgatt tatctcataa attatataca cctaaacttt
    55201 ctgagtatat tgctgatata aatccagatt tgattatctc tacatttcca ctagctgctg
    55261 cttgtgtaaa taactttaag ataaaaaatc ctgatataaa tatacctaca cttacagtta
    55321 taacagatgt tgtagatagt atggaatggg tttttgaaaa tacagatttg tattttgttc
    55381 cttctcctga aataaaaaat agattttttc agaaaggaat aaatccagac tccataaagg
    55441 ttactggagt tcctgttgat aagagatttc aaattgaaag taaagaacta tgttgtgata
    55501 aatatagact attacttcta ggtggaggaa gaggtctatt tgatatagat gaggatttta
    55561 tgcattggat agatgaattt attgaagaac atagtaattc tatagaaatt acaatagtta
    55621 ctggtaaaaa caaaaaatta tatgacaatc taactcataa aaaacctcta aaaaatatta
    55681 aagtacttgg atttgtaaac gacatgtata atctaataag agaatgtgac ctaatgctaa
    55741 ctaagcctgg aggagcaact atatttgaag ctattcaatc acaaactcca gtactcgtaa
    55801 aaatgccaaa agttggacaa gaaattgaaa acgctaaatt tataatagat aagggtcttg
    55861 gcatgattta tagtgatgac ctagacctta aaaacatatt ttataaatta gtatcaaatg
    55921 aatttgattc tataataaac tttatgaaaa aaaatttaaa agaatttaaa acagtcattc
    55981 atccagagaa aattgctgat tatatatcag aattaataga taatcattac agttaaattg
    56041 tactattaaa aaatttcaaa cataaaatta aaggcaatca agtatgcttt tacacttgag
    56101 aatttactca tagtgtttaa taatacttga ttgcctttat catatcaaaa tcaaattgtt
    56161 atattagtat atatttttct tgtactgcat atacagttgt tgtatttctt ccatacttct
    56221 ctttaattct atttgtaaat ctgaagcagt ctggtaatcc ttattttcta tagcttctct
    56281 cactctagtg aatagtgatt ctctagttaa agtatccttc ataatattga actttaaatc
    56341 cgatattgag ttccaaacta cctcatcaag cgcatccata ttttcttttg tgtgtatctt
    56401 gacaatactt cttatttttt gaatcccagc ctctattatt ctagttttta atttcttttg
    56461 ccacttatct atagctccaa tcttaaatga ttctattata ctatcagtaa atacatcacc
    56521 ttgttttaaa gattttaatt ttgaagcata tatttctaag tttttcatat tttcataaac
    56581 tgtagccggt ggtattccaa atcttgcatt tctttcttcc aaactataat gttcaaatac
    56641 atcattttca tctctatatg ctctatcttt ttctaaatag aaactttctt cacctacatt
    56701 tttagataac tctttttcaa gttcttttgt actaagacca ctcttagctg ctgcttttat
    56761 accatccaac attgtttgat aacatcctgc tattactaaa tacgtgttag atagagggct
    56821 tggtgacctt aactcaaatc ttacagtctt tggatttttc atatctctta ttaatccaac
    56881 aagcactgac ctatttcttg atggaatctc ataactatga cctaaagatg taactatgca
    56941 tacaggagct tcaaatccag gaactaatct attaaatcca tcattagaag ctgttacaat
    57001 tgggtttaat acttcataat tgtaaagaag tcccataaga gccccatatc ctagttcact
    57061 tagataatct tcttttaaat cttttggcgc aaatagattt tttatacttc catcctttaa
    57121 cttcgcactt actcctacat gtgtatgtcc accacttcct gctactccat gaattggttt
    57181 tgctttaaat gtaacttcta gtccatgtga tgtaaataca tcctctataa catctcttac
    57241 taataattca ttgtctgctg cttgtaacgg tgtagaaaac ttccaagaaa cctctaattg
    57301 ctccatagca tggtttgttc ttccatctat actaatagaa ctttgtattc ctccgacctc
    57361 tttgtgagcc atttcagggt ttacacctag cttttgaagt ataattaaac ttttctctaa
    57421 acaagttctt ataataccat gagttctttt ccagtattgc tcttttaggc tttgtgatac
    57481 atataatttc tctaagtcag ctttatcctc aggagtatta acccagaact caagttctgt
    57541 agctgctgtt aacattattt cctctatatc atctactgaa tctattccta tgttatttat
    57601 tacatgtgga tattctctaa atatttcata cattgacttt ttaaagtact tatctgcttt
    57661 ttgaagtact cctctagaac atactttttt attatcatgt attaaaaatg caggtatctt
    57721 taatgttcca acaggtagac ctacttcttc gtctatatat tccatattgt aatctacata
    57781 ccaatgacaa cttttatctg gcattaaatc tactttcgca ttatttaatg tagctatatt
    57841 ataaagctca acacttgaac catcagtctg tatagctgat tccaaaaatt tatctatatc
    57901 ctccaaaaat aattctacag gaatcttttc atctgttgca tttcctccta aatcaacccc
    57961 cattaaggaa acaaatctta tatttttatt gctttttagg atttctctta attcttcatt
    58021 agtgtgttta tctttctcta ttacgtataa tagactatcc atttttccac tctcccataa
    58081 tttttatgta tattttattt tgttaaatac aagataaatt tcattttcct tacatttatg
    58141 aatttttctt gcaaattatt cgtgttttat tcgtgttttt atttatatta ttatatatca
    58201 agtataaaaa gttcgcaata ttttttattg gaaaaaatat tatacataca atagtttaac
    58261 atttttacaa atatggggta tactaaaata aaagtatttt tatttgaaaa tttaatttta
    58321 tttataatat aatctatagt aaaagaaata ataaaaaaat ttaggagata aactttatgg
    58381 aatacataat tttcgatttg gaatttaacc aaggatttga taaaaaactc aataaaactg
    58441 tatccaatga aaagtgtcct tttgaaatta tacaaatagg agcaattaaa ttggattcta
    58501 aattcaatat aatagatacg tttaatagct atgtaaaacc tacaatttat aaagacatac
    58561 atccctttat tagtcgtatg actaatatta aaagttctga ttttaatgat tcgcctactt
    58621 tccctgaggt ctacaacaat tttataaaat ttatatcatc acaagaccct atattatgtg
    58681 tttggggagc tggagatttg aaggaattat acaggaatat caactatcac aagctaccat
    58741 caaattcctt acctaaatct tatattaata tacaacaaca tgcatctaaa tatttcaata
    58801 atccagcagg aaaaagcatt ggcctacaaa atgctatttc tatattggaa cttgatgaaa
    58861 aaatgtctta tcacaatgct ttaaatgatg catattatac tgctaaagtt tttattaaga
    58921 tatacaatcc aagtatagtc ccagatatat atctttatac gagtataaaa cctaaaacta
    58981 taagatattc taacaaaaaa agagttgatt atgataagtt atttgatgaa tttaggaaaa
    59041 ttttaaatcg tgaattaact aaagacgaga aaaaaatcat taacttagct tataatatgt
    59101 ggaaaacaaa tcaatttaca ttagaaaatg ttaagcaaag aaaaaacaaa tagagtttat
    59161 ttagataaaa aataggcatg tagattaaaa aactagttaa ctttaaattt atatctacag
    59221 cccaattttt atcataatta atttttattt tatctctaat tcaactggac aatggtctga
    59281 acctaatatt tcagtgtgta tatccgcact tactaatcta tcttctaatt ttttggatgc
    59341 acaaaaataa tctattctcc accctgcatt attttttctt gcattaaatc tatacgacca
    59401 ccaactataa acaccttctt tatcaggatt aaaatatcta tatgtgtcta taaacccact
    59461 gtctaataat ttagaaaact tctctctttc ttctttagta aaacctgcat ttttcatatt
    59521 atttttagga ttttttaaat ctatttcttt atgtgcaacg ttcatatctc cacacacaat
    59581 tacaggctta tgattatcta gtttggttaa ataatctata aagtcgtctt cccatctagt
    59641 tctatattct agtctcttta attcagattg agaatttggc gtatatactg taacaaagta
    59701 aaaatcttca aactctagag ttatcactct accctctttg tcatgttctt ctatatttat
    59761 tccatacatt acttttaaag gctctttttt tgtaaatata gcagtacctg aataaccctt
    59821 tctctcagca taattccaat attgaaaata tcctggtaaa tctaactcta tttgcccttc
    59881 ttgcaattta gtttcttgta aacaaaatat atctgcatct acttctttga aaaagtctaa
    59941 aaatcctttc ccaacacaag ctcttattcc attaacattc catgatataa atttcatact
    60001 tatactcctc atctaaacat tgacacactc cccatagcta aagatggggg cttttcaaca
    60061 attttattgt aaattcttaa tttactttta ttttaacaat gctatactat aatttcatct
    60121 aaaattacta tttacttaat acctaaaaat atatgtttta atcaattttt aacttttttg
    60181 ttaaatcttc agggctcatt gaagaaacat acatatttgt tccaagttca aatcctccaa
    60241 aattatattt tcttgggatt atgtgcatat gaacattaaa atacgatttt gtttcaatct
    60301 ttgttggatg agtgtgaata cataaattaa atggcatata tccattgata ttgtataact
    60361 tcttaaacaa cttttcaaat attgtagaaa gctcctgtat attattatca tttaactcac
    60421 caaactctat tttatcttta aatattattc ttacttctcc actatacttg gttgcatatg
    60481 gtataagtac caaaaaagct tctccattat aaacaactct tctatctaaa cttatttcat
    60541 tttctattaa atcatcatac aaagagcttt tattgctgtc ataatactcc tttgaaacca
    60601 acagttcatt cgtaatttca ggtggaataa aagacataga caatatttga gcatgtggat
    60661 gcatcaaaga tgctcctgcc tttctcaaga agtttttgaa gatactaaca tactctactt
    60721 tatcatcttt cgacaaatct ctaaatctat ttctatacat aaaaaaaaca tcttcaaatt
    60781 ctttttgact catgttataa aaactacgat tatgtttatc gctctctatc attacttcat
    60841 gaacaccata tacatctctt gccatatcat caattatagg aaatttattg tagacagatt
    60901 ttacaagcca tccttcttca ctatctattt caaataatgc atcagttgca tgagcttcat
    60961 ttcctttgca aaatgggcat tcttcatcat attcattagt ttcttcatct tcatttggga
    61021 tatctgctgt atctaaaggt ctttttaacc tatctgtagc aaatataaca acatcattgg
    61081 taattggatc tattcttaat tctttcataa ttaacacctc ttagttaata gcctttaata
    61141 taattatatg atatttatcg tatctgttaa ataaatttat aatatttttt ataattttgc
    61201 atatttatta ttatatattt tgtctatagc tgaaagatta taactaaaaa atcactatca
    61261 gtacatcaga atattatctt actataaatt aatttatgaa tacataattt agtggcataa
    61321 acatgggtat tttactataa tttgttaaaa gtttatttta aagctatatt aatttttttt
    61381 gatgattttt acccataagt atgttattat tatcttgtaa agatgtcttg tattcaaaca
    61441 tacaatttac ataatacaat atacgtattt aaattaaata gggggtatta aaatgaatta
    61501 ttcaaacaga gttagtgcaa tgcaagcctc tccaatcaga aaacttgttc catttgcaca
    61561 agcagcaaaa gataaaggaa tcaaagtata tcacttaaac ataggacaac cagacataaa
    61621 aactcctaaa ggattttttg atgctgttaa aaactttgat agcgaagtct tagaatatgc
    61681 tacatcagaa ggtattccag aattattaga agcacttcaa aattactata aaacttacga
    61741 tatgaatttt gaaaaagatg aattattagt aactaacggt ggtagtgaag ctttactttt
    61801 cactatgatg gcagtttgtg acccaggaga taatctatta gttccagaac cattctatac
    61861 aaactacaat ggatttggtc aatctgtaaa cgtagaagtt aatgctgtta caacaaaggc
    61921 agaaaacggt ttccaccttc catctaaaga agaaatattg tctaaagtag atgataaaac
    61981 taaggctata attctttcta acccaggaaa tccaactggt gcaatttata caaaagaaga
    62041 acttaatatc ctagctgaaa tagctaaaga aaaagattta tggataatag cagacgaagt
    62101 ttatagagaa tttgtttatg atgggcttga gtatacaagc tgtggtaact tagagggtgt
    62161 acaggataga gttataataa tagacagtgt ttctaagaga tacagtgctt gtggtgctag
    62221 aattggttct atcgcttgca aaaataaagg tcttatcgct caaatactta aattatgtca
    62281 aggaagactt tgtgttccta cattagagca aataggagct gttgagttat acaaaactcc
    62341 tgtttcttac ttcaaagaag ttaatgaaga gtacaaaaaa agaagagatg tattatacaa
    62401 tgaattaatg aaggttgaag gtgttatatg taaaaaacca actggtgctt tctatatagt
    62461 tgctaaatta ccagttgaaa atgcagaaga tttcacaatt tggatgttaa aagaatttaa
    62521 taaagataat gaaacagtta tggtttgccc tgctgaagga ttctatgcta ctccaggttt
    62581 aggacgtgat gaaataagat tagcttacat cttaaatgaa aaagaccttc atagagctgc
    62641 tacattatta aaagaaggtt tagagcaata tgtagcttta caaaaataat tttttaaact
    62701 taatttatat aaatttaatg atataaaatg tccccttttc agatattatt tgaaaagggg
    62761 acatttctta attaatatat taattaagac ttagacctga ctatttttca ttttctttat
    62821 atagtgttgg ccagtaatct ttattcactt taattaaagc atctaaaact tgtcttgcct
    62881 tagttagaga aattataaaa aagtacatca agaaaattta agatgtactt tttagattgt
    62941 atttagactt ataattatat agttaaatga ataacaaaga attaatctta gtaccattaa
    63001 atacaaaaat ttttatattt tttctatcta aattcttctt tgtttaatat atattgaaga
    63061 gtatttattg cttctaaata tttttttctg tcttcttcag ttaatttaga aagtttttct
    63121 cctaaaccat cacttaattt atccataaaa tcagttgcta tcttatctcc ctcttcagta
    63181 atgtcaatta gatattttct tctatcaact aaatctcttt tccttgttac atacttctta
    63241 tcagttaaat catcaaccat actagttaaa ctgccttttt ctatatttaa cttagagcat
    63301 aaatcagtca tacttattac tccataattt tttatgaaaa ctaatgctct taattgtgtt
    63361 ttatttacat tataatctgg tgcaaatttt tttaggtctt ctaagtacag gctagaataa
    63421 atcttaggaa atgtttttac taaaaaactt atggtatctt ttactatata gttcatataa
    63481 tcacctcggt tgttttaaaa tttattaaat tatctaaata actttatttc agtttacatt
    63541 aaaaatattg caagtacaat agtttttgct gaatgtttaa atttaattag taatcttatc
    63601 atttttttat ttttatttat attattccta ttaaatatta tttatatagc tattttatta
    63661 aattcatggt atagtaagta aagaagaact cttcacagcg gtggagagaa gacgctagcc
    63721 cattaaaatg gctatcttat ttataaataa gatagccgtt tttaattata ttttatctgt
    63781 acaattctat actcttaggt ctacatctac ttttcctaag tcttccttat aatcttttat
    63841 agcaggttct acaacttcat ttacaaattc tacaacttgt tctggagctc tacctataaa
    63901 gttttttggg tccattatag atagtatttc ttccttgctc attttaaatg aatcatcatt
    63961 cattataagt tcaattaagt tattatcctt gccttcatgc tttactctat aggcagcttt
    64021 catagaatat tctcttatta tttcatgcaa ttcctgtcta tctccacctc tttttacagc
    64081 ttccataagt attgtttctg tagccataaa aggaagttct tcatttacac gtctatttat
    64141 catattttca tatactacta aaccatcagt tacatttatc cctatttcaa gtatagcatc
    64201 tgctgccata aatgcttgag gtattgccaa tctcttattg gctgagtcat ctaatgttct
    64261 ctctaaccat tgagtggctt gtaccattgc agggcttata gattcagaga ttatatactt
    64321 agataaagat gctattctct cacttctcat tggattcctc ttataagcca ttgctgatga
    64381 acctatttga tttttttcaa atggctcttc taattctttt aaactttgta aaagtcttat
    64441 atcattagtc atcttatgca tactttgagc tatccctgat agtatgctta ttacttgata
    64501 atctaacttt ctagtatatg tctgtccact tactgcatag gaagaatggt atcccatctt
    64561 tttacaaatt ttcttatcta actcttttac tttttcgtgg tctccttcaa ataagcttaa
    64621 aaaacttgct tgagtaccag tagtaccttt aactcctctt aacttcatgt tgtctattct
    64681 atagtttaaa tcttccaaat caagaattaa atcttgagcc cataaacaag ctctttttcc
    64741 tactgttgta agttgagcag cttggaagtg tgtaaatcca agagctggca tatctttgta
    64801 cttaagtgca aattctttta aattgtttat taaatttaca agctttactc ttagaagttt
    64861 taaagcttca ttcatttgta taacatctgt attatctcca acatatgcag atgttgctcc
    64921 taaatgtatt attcctttgg ctttttcaca ttgtaaacca taagctttta cgtgagacat
    64981 tacatcatgt cttacttctt tttctatttt tctagcttca tcaaaattta tattatctat
    65041 attagctctt agctcatcta attgttcttc agttatattg attcctaact catgttcacc
    65101 ttctgcaagt gcaacccata accttctcca tgtagagaat ttaaattgtg gagaaaatat
    65161 ataactcatg tccttgctac aatatctgtc tgtaagtggg tttgagtaag tagtatattt
    65221 attatctatc attatattag caccttcctt aaatcttttg tcgtgtgatt actgtgtaca
    65281 cattagtaca taaataatta tatataattt tacgaactat aacaagactt ttttattttt
    65341 tgttcacatt tatatatagt attttttatt tattactatt ttttatttat atccaaatta
    65401 tctttttcaa ttaagtaatc cactatttca ctatcaacaa aatttaatac atacttatat
    65461 ctaattgcat agtatttatc actccatcca agctgatttt ttacatcact ttcatctgcc
    65521 ccaagcctta aacttattgc tgcaaatgaa tgtctaaaat ctcttgctga atattgagaa
    65581 agtccagcta aatctaatgc ttttttgact ataagtctga catttctatc tgttatagaa
    65641 ttactctttt gagttgtaaa aataaaatca tcactaggta ttattacctc tggaagccca
    65701 gaataattcc tgtaatcttc taaaagttta aaaaagtatg gatgtaattt aactactctt
    65761 tcttttcttc ccttacctaa ccttacatat gagttatcgt tttcatctac cataaggtct
    65821 ttccacttta agctaactaa ttcatttaat aaacacccag tagtaactag acagactatt
    65881 attactctat ctcttatatt taattttggt aggataccta taagtttatt tatttcttgt
    65941 atacttagaa catcatcttt tgtttttatt cttgttactg tgggtttttc tacatatcta
    66001 aatggattta tatctatgta tccttctttt tttaagaagt tataaaaact atgtaaataa
    66061 ctatatatct tttcacaagt tgatttcgca tatttagtct gtatatagtc tacaaaattt
    66121 ttacaatctt ctttcgtagc ataaatcaat tctttccctt ttaaaaattc tttaaacagt
    66181 ataacctttg ataaataatc gtgtttcgtg tttggattta attttgtaga aaaaacatta
    66241 aaagtttcat actcataatc atctagtatt tttgtactat acataataac tcctttcctt
    66301 ttcataaaat aaaatagcta tacttttact ataccatata tttccccctc aaatataccc
    66361 cttattcaat agataacttt taagtttatt ttgttatatt atgaaggttt tatgaaaata
    66421 tcaatcttcc attgtgcact acacagtact atggtattat aagttagtaa aaggtggcat
    66481 ttttttatta atctatgaat aaaatatgct actataaatt tgtattggag gtattttgat
    66541 ttggaaacat ttagtttgct tgaaattttt aaggcagtca ttttgggcat agttcaggga
    66601 ataacagaat ggctaccagt aagtagtaca gggcatatga tattagttga tgagtttata
    66661 aaattgaatt tttcaaatac atttataagt acatttttag ttgtaattca atttggttca
    66721 atattagctg tacttgttat attttttaga aaattaaatc cttttgatag cgcaaagaat
    66781 attaagcaga aaaaagaaac agtccgttta tggcttaagg ttataattgc agttatacca
    66841 tctggagtta ttggaatact gtttgaagat gatatagata gattattctt taattcaaca
    66901 gtagttgcta ttgctcttat tgtatatggt ataataatga tagggcttga aaagagaaat
    66961 aaaaaaccta agtataaaga tttttctcaa gttacatata aattagctct ttgtatagga
    67021 ttattccagt gtctagctct tataccaggt acatctaggt ctggttctac tataataggt
    67081 gcagtattac ttggtacttc tagatatgta gcagcagagt tttcattctt cttagccatc
    67141 cctacaatgc ttggagctag tgcattaaaa cttctaaaag ctggatttgg atttactgga
    67201 tttgaatggc ttattttagg tgttggttct gtagtagcat ttgttgtttc aattgtagtt
    67261 attaaatttt ttatggacta tatcaaaaaa catgacttca aagtatttgg ttattataga
    67321 atagtcttgg gtatagtggt tcttgcttat ttctttctat tataatgtat tctaatttaa
    67381 taacaaatga taaggagaaa agttatgagt gttaaaaaag aaatatttga ttggattaag
    67441 tcaatagcta tggctattgt acttgcattt gtaattctac aatttataag accttctatt
    67501 gtaagtggag aatcaatgta tcctacttta gatgataaag attatctgat tttaaatagg
    67561 atatcataca aggttggtaa acctgaaaaa ggcgatattg tagtttttaa aaccaattta
    67621 gttgatggag aaacaggaaa gaaaaaagac ttaataaaaa gagttatagc tactgaaggt
    67681 gacagaataa aaatatcaaa ttctaaagtg tatgtaaatg gaaaattatt aaatgaacca
    67741 tatatacaca ataactatac ttctggagat atagatactg ttgttccaaa aggtaaacta
    67801 tttgcaatgg gagataatag agaaaatagt aatgatagta gattccctga tgtaggtatg
    67861 gttgatgaag atgaagttct tggtaaggtt atggtgagac tattacctct tgataatatt
    67921 gggaaagtag actaaaaaat aagagactga attggtaaag tttattttac aaatctcagt
    67981 ctctttttat tttcttaaat tacaaatatt tttttactaa atatcttttg attctgtaat
    68041 aagtcttatt atatcacttg cttcttcatt aaaagttgtt actatactta ggtagtctgt
    68101 tgctctactc atagctaaat aaaccttatt taaatctcct acaaagtcat ttacttgata
    68161 atcttgttca atatcattta tagtttgatt gtataacatc tctaattcac atactattac
    68221 cgctttatac tctaaattct ttattgcata tatatttgct attgtagttc ctaccttctt
    68281 acttatattt gtcaaattat cttctgcaca tatataagga atttttgcct cttccaatgc
    68341 tttttttaac atatattgaa agtaaatggt ttttccactt tttaatttct tcttattgta
    68401 aggataaacg atagcaactt cagaataatc aagacctttt ttacttatta aatactcaat
    68461 ttcccagatt acagaactta tttggtcatc aaggtcactt acttttatta tatcaacaga
    68521 cttatttcca cctctaagtg ctttagtata aaagaaagta ctaaattctg tatttggtct
    68581 taattcgttg atatatgagt tagaattatt tgaaaattta tttgtaaaat ctacaatctc
    68641 tttagcttgt ctataatttt tacttaagat aatcttatca tcaaattcta taccattata
    68701 taatttttta aatatattca atctattaga gatattcaag gagttacaag aacacacatt
    68761 aaatatgaat tttgttttat ataaaaactc ccttataaaa tctatttcat actctaaaaa
    68821 gctttctgct tcatcaataa aaatagcctt gaacatattt ttatttttta taatgttctg
    68881 tgcttgtttt acaagattat taaaggtctt ttcgtaatca ttttttaaca tgttataatc
    68941 tacaattaaa ttgaattttt tagctagttt aaatataaaa gaactaaatg tgtgaacttc
    69001 taaattgtta ttatctttgt ataataactc tatcctctct cgaagctcat tgcacagttg
    69061 ttttgtatgt gtaaatatga ctaatttatg atgtggatat acttttgcta attttatagc
    69121 cctagaaagc ataattgctg ttttgcctat accagaacca ccttcaataa gtgtattccc
    69181 atatttaata gaaacaacat ctttaatttg aacgtcttcc atcatagttg ctgtatactt
    69241 atagtcatca ttgtagaatg aaattttttt aaatttttca tttagatgaa gtttatcatt
    69301 tattatatag tattctgaac atatgtctag taaaaataaa tttaagttta tttcatcatt
    69361 ctcatcatta agatattcct ccagcgaacc cttattcatt atatcttgaa gcttattttt
    69421 atctattata ttattattaa caaattcttc aaattcatat gtttcctcaa cttcaacgta
    69481 tggcataatg taaacgtagt tataacttat atttctattc ttttgtccca tttttagttt
    69541 caaaagttca tattcctcat tcataacttc aagtaactct tcttctaaaa taaaaaatat
    69601 atcttctgtt gtatccataa attttataaa taaaattctt ccatctttaa catacaacaa
    69661 atcggtattt attcctttaa aaggagtaac ttttggcact actttaacgt cctcattgat
    69721 attttcgtaa aatattttct cgaactcctt caattttagg gcgtctaact gagaatttat
    69781 atttatgtat tggctcactt acattacctc cttctgttat acttaattat accattttga
    69841 actatatttt tatatatact ttttataggc aaatttagta aataaattca aaataaatac
    69901 aaataaatac aaaactgcta aaaaaatttt gcaataagta tagatattta ttgttataaa
    69961 atactttctg taaataataa aatgataaat ttcataatta atgcttaaaa taataagtaa
    70021 agtcttaaaa aaaataaatc ttgttagcca aaaataagat ttattataaa aaatttaaaa
    70081 acctgctaaa aataatctat tttcattagc aggttttatt tataatcttc ttatattaat
    70141 actattatat cctattttta gattttactg tagtatttac tatttatttt ctagtaaagt
    70201 attgatactt gatatgtctg tataaatcgc ataaaaaaca ggataacgat tttgatataa
    70261 ttcacttaca aacttacctt gcatccttac aggaaaaata tgaccatctg tatgacaaaa
    70321 acgaaaaact atttcaaaag tctctctttt agaaattgct tctcttaatg tatctagtac
    70381 catttgtaag tcgtcttgta atacaggcga aaaaatatca aaacctatag aagtaacagt
    70441 ttgagctgaa tatccagtaa attcaagcat tttttggttg aaataaagta attttaagtt
    70501 ttccatacaa gcaaatttga caacaccatc agtagccatt tctaataata cttttatatc
    70561 tctagagtct atatgaaatg aaatactatc aatagaatcc tctgaaaata tatgataaga
    70621 atttttccca tggctttttg catagtaaag tgcttggtct gctttctcat atagttcaga
    70681 gtatacatat ccatgttcag gatacattgc tacaccaata ctacatgcaa tagaaaattc
    70741 tgcttgctca acaaattttt tctgattaat cttagaacaa aaacgctcta atttgtctat
    70801 aagcacatag ttattattat taaagtcttt tattaatact acaaactcat ctccaccaat
    70861 acgtcccaca atatcgtcct cacgaaattg agattttaat tctaaggcaa attcacttat
    70921 aacaaagtct ccaaatacat gaccatattt atcatttaca tttttaaaat tatcaatatc
    70981 gaaaattaga aaaacgtgtt ctaaatcttg attactttca ttttttaaaa atgaacgaat
    71041 aaattcctct gttgtagctt tattgtaaag ccctgtaaga gaatcacgtt gtgaacgttc
    71101 gagaagtagt aattctctat ttttttcttc atctatattt ttacgataag atatcatacg
    71161 aacagattca tctgatgtcc aaaagaaaat tcgtgcatta attctaatcc aatgataact
    71221 ttcttcatct tttttaatta aaaaatcata gctgatatta ttaattccgc tattataacg
    71281 tttaattaca ttttcaggta aaaatgtatc taaataacct tgtgcatatt cttctttgat
    71341 ttggttttta gctattgtat gtaaggcttc atcatatggg gtattaagcc ctaatccaaa
    71401 ttcatgaaaa tacctattct catcttcaca accagcttta ttgttagtaa tatcaatttc
    71461 aaaaatattt tcataaagac cttcagtaga tttgctcaac aatttttgat attccaattt
    71521 ctgtgaaaca ctaagcttta ttatttggtt tttgtatttt ttaagcacat gtgtaatagt
    71581 aaaaagtaca aatattataa ttaaaactat aactgcaatg cctttaaaaa attgcagatg
    71641 aagctgttta atcattaaag taaaatcatt ttctagaaca agatgccatt ttaaactagg
    71701 tatgtactga catacaatat aactttttga tttttcagat gaataccaaa aactcttttg
    71761 ttcctttttg ttgtttaata ttaattgttt cgaattagac aagtcgctac tagaattttc
    71821 aaaaaaattt atattctcat gaccggtttt atctactgct aattgtacaa accctttatc
    71881 atcaattaag cgtgcaacaa catcaaattt gtcattatat cctttaagca acatttgtaa
    71941 tgaattaacc tttaacccaa cacctataat tcccatagtt gctccattat catcttttat
    72001 cttacaattt acaaagactg taatactatt gttacttgct tcatcattat caacatttaa
    72061 tgagtattca tcatcattct ttaagaaagt ataataccat tgattctctg agttattagc
    72121 gctaagattt ctatcaagtc cattaaaatg ataataatta ttggttttag ttgatactaa
    72181 aaaaacagaa tcatatgaat atttatttct atacacattc agataatctt gtaatttata
    72241 aataaattct tcatcattta aatgttcttt ctcaccatct aaaaaatttt ttaatagact
    72301 gtcatttgcc attgtaagag atacatttat aggttctgaa agtagtttat ctatctgata
    72361 ataaatacct tcagcagcca atgtagatac atgttcaata tcatttttaa aaatattggt
    72421 attagattga tatccaatta tagaggtagc cacaaaacca agagtaataa taatgcaaac
    72481 cataatattt gtatgtaaaa gtgtattttt tttcatagtg taccctctct ctaatcctca
    72541 ctttagcgtc attgtatttt catcttattt aagtacaagc attccaagta gtaatatatt
    72601 tattttacaa cttcattata tcaaacaaac ttggataatt atataaataa tacatatata
    72661 aagctttatt ttattaatct tttgtaagta gcacttttag cacttagatt atttttgcat
    72721 tatataaaat taaacttaaa caatttaaaa gccacaagat atattatcat atcttgtggc
    72781 aaatttaaat ttctaaaaat attttcttat tatttagata ttatttcttt tacttcgcat
    72841 actctatagc tcttgtttct cttattatgc ttacttttat ttgtccagga tattcaagtt
    72901 catcctctat tttcttagtc atatctctag ccaatagatg tatttcttca tcatttatag
    72961 cttctggttt taccattatt cttatttctc taccagcttg tatagcaaat gatttttcta
    73021 caccttcata tgaattagct atttcttcta atttttcaag tctctttata tatgcttcta
    73081 aagtttctct tctcgcacca ggtctagcag ctgatattgc atctgctgct gtaactaata
    73141 cagcctctac tgtttgaggc tcgtaatctc catgatgagt actcatggca tgtataactt
    73201 ctttagactc tttataacgt ctaagtaaat ccatacctat ttcaacatgt gtaccttcca
    73261 tttcatggtc tacagcctta cctatatcat gtaataaacc tgccctctta gccaatctaa
    73321 tatctgctcc tatttcagca gccattatac cagctatatg agcaacttct atagaatgtt
    73381 taagtacatt ttgtccataa ctagttctat agttaagtct acctaataat cttattaatt
    73441 ccggatgaat cccatgtaca ctagtttcaa atgcagcttg ttcaccatat tcttttataa
    73501 tattgtcaac ttcttttctc gccttttcaa ccatttcttc aattctagct ggatgtattc
    73561 ttccatctgc tattaatttt tctagagcaa ttcttgcaat ttctcttctt attggatcaa
    73621 atcctgataa aattacggct tctggagtgt catctattat aaggtctata cctgttaagg
    73681 tttctaaagt ccttatattt ctaccttccc tacctattat tctacctttc atttcatcat
    73741 taggcaagct tactactgtt acagtagttt cggctacgtg atctgctgca catttttgaa
    73801 ttgcatatcc tataatttct cttgatttct tatcagcttc ttctttagct tgactttcta
    73861 tctcttttat cattatagac atttcacgtc ttacatctct ctccgcattg gttaagatga
    73921 tttctttggc cttatcagaa gtaattcctg atatactttc taatttttct aactgttgag
    73981 tttttattac ttcaacttct tcttctttct tttccactac ctttaatttt tcacttaggt
    74041 ttacttcttt agattctaaa ttttgtaatt ttctatctaa gacttcttct ttttgtacta
    74101 ctcttttttc atacttttgt acttctgttc ttctttctct gttttctctt tcagcttctg
    74161 ttctccactt atggatctct tctttagctt ctagtaattt ttctttttgt actgtttctg
    74221 agtcgtggtg tgctttatct attatttctt tggccaagtt ttcagcttgt ccaatttttg
    74281 cttcagatat attttttcta acaaaatatc cagctataat accaacagct gcacctatta
    74341 caatcattac tacactatct atgacatcca cctccttcgt taataatccc aaaatgtcat
    74401 cactatgatt aaaaaatatt cctaataatt aaaattaaat ttagatattt tatcctcact
    74461 taattttata attttttcaa cattgtgtca agctaatagg gagcgtggca tgtctttaat
    74521 tactagttat ttttttgtat ttttacttat tcttctacaa tttcttttga tactgaagta
    74581 cctgattctt catgttcttc atttaaattg taaaatgctc taactttctc atctatttca
    74641 gtagttaaat ctaaattatc ttccaagaat tttttaacat tttctcttcc ttgtccaagt
    74701 ttagtatcat tgtaactata ccatgaacct gattttttaa ctatatctac atcagcagct
    74761 atatctaaaa ggtctccaat ttttgaaatc ccttctccat acattatatc aaattcagct
    74821 tgcttaaatg gtggtgctac tttgttttta acaactttaa ctctagttct actacctata
    74881 actttatcac cttgttttat tgtatctatt tttctaacat ccaatctaac tgatgaatag
    74941 aattttagtg cacgtcctcc agtagtagtt tctgggtttc caaacattat tcctactttc
    75001 tctcttaact ggtttataaa tatagcaaca caatttgatt ttttaattga accagttaac
    75061 tttctaagtg cttgtgacat aagtctagct tgtaaaccta catgagaatc acccatatct
    75121 ccatctattt cagcctttgg aactaatgct gctactgagt ctattactat tatatctatc
    75181 gctccacttc ttatcaatgc ctctgctatc tctaaagcct gttcacctgt atctggttga
    75241 gatattatta ggttatcaac atccacaccc aaagcttttg catatactgg gtcaagtgca
    75301 tgttctgcat ctataaatgc agctattcct ccatcttttt gagctgatgc tacacaacta
    75361 agcgcaacag tagtcttacc agaagattct ggaccatata cttcaactat tctccctcta
    75421 ggtagacctc ctataccaat agctatgtct aaaccaatcg ctcctgttga tataacatct
    75481 atagacatag atgttgcttc tcccaatttc attactgaac ctttaccaaa atctttttca
    75541 attttaccta aagcttcatt caacgctttt aatttttctt gatctacact catctctata
    75601 ccatcccttc atttatctac aaacatttgt tctcttgtta tatattaatt atataacata
    75661 aatcaaacct agtcaattta aaaacgctac taatgattat atttttattc attacatttt
    75721 atttataaac cattattaat aattatatac acaaaagaaa atattctt
//
LOCUS       DAYAKB010000011        72710 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.011, whole genome shotgun sequence.
ACCESSION   DAYAKB010000011 DAYAKB010000000
VERSION     DAYAKB010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.011"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            248..679
                     /gene="phnG"
                     /locus_tag="ACGI3L_000884"
     CDS             248..679
                     /gene="phnG"
                     /locus_tag="ACGI3L_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HFG9196611.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            694..1269
                     /gene="phnH"
                     /locus_tag="ACGI3L_000885"
     CDS             694..1269
                     /gene="phnH"
                     /locus_tag="ACGI3L_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HFG9196612.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTNLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            1272..2387
                     /locus_tag="ACGI3L_000886"
     CDS             1272..2387
                     /locus_tag="ACGI3L_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HFG9196613.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRAAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKIKHPIYEDEEITIGDMLVTECEIVSKASQNK
                     TENSKNNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIKKFEEVSLGDI"
     gene            2377..3246
                     /locus_tag="ACGI3L_000887"
     CDS             2377..3246
                     /locus_tag="ACGI3L_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HFG9196614.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            3239..4105
                     /locus_tag="ACGI3L_000888"
     CDS             3239..4105
                     /locus_tag="ACGI3L_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196615.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQREFKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            4146..4859
                     /locus_tag="ACGI3L_000889"
     CDS             4146..4859
                     /locus_tag="ACGI3L_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HFG9196616.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            4860..6029
                     /locus_tag="ACGI3L_000890"
     CDS             4860..6029
                     /locus_tag="ACGI3L_000890"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HFG9196617.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            6033..6869
                     /locus_tag="ACGI3L_000891"
     CDS             6033..6869
                     /locus_tag="ACGI3L_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFG9196618.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            6870..7865
                     /locus_tag="ACGI3L_000892"
     CDS             6870..7865
                     /locus_tag="ACGI3L_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196619.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            7883..9571
                     /locus_tag="ACGI3L_000893"
     CDS             7883..9571
                     /locus_tag="ACGI3L_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HFG9196620.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     EFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            9583..10650
                     /locus_tag="ACGI3L_000894"
     CDS             9583..10650
                     /locus_tag="ACGI3L_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9196621.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            11414..12481
                     /locus_tag="ACGI3L_000895"
     CDS             11414..12481
                     /locus_tag="ACGI3L_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9196622.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNSAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            12673..13203
                     /gene="rnmV"
                     /locus_tag="ACGI3L_000896"
     CDS             12673..13203
                     /gene="rnmV"
                     /locus_tag="ACGI3L_000896"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFG9196623.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            13374..14243
                     /gene="rsmA"
                     /locus_tag="ACGI3L_000897"
     CDS             13374..14243
                     /gene="rsmA"
                     /locus_tag="ACGI3L_000897"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFG9196624.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            14309..15571
                     /locus_tag="ACGI3L_000898"
     CDS             14309..15571
                     /locus_tag="ACGI3L_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196625.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEENEESDRDEDSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSDDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            15722..16837
                     /locus_tag="ACGI3L_000899"
     CDS             15722..16837
                     /locus_tag="ACGI3L_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9196626.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            17023..17919
                     /locus_tag="ACGI3L_000900"
     CDS             17023..17919
                     /locus_tag="ACGI3L_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFG9196627.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            17989..18786
                     /locus_tag="ACGI3L_000901"
     CDS             17989..18786
                     /locus_tag="ACGI3L_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196628.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(18841..20193)
                     /gene="murC"
                     /locus_tag="ACGI3L_000902"
     CDS             complement(18841..20193)
                     /gene="murC"
                     /locus_tag="ACGI3L_000902"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFG9196629.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            20412..21290
                     /gene="purR"
                     /locus_tag="ACGI3L_000903"
     CDS             20412..21290
                     /gene="purR"
                     /locus_tag="ACGI3L_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFG9196630.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            21446..21724
                     /gene="spoVG"
                     /locus_tag="ACGI3L_000904"
     CDS             21446..21724
                     /gene="spoVG"
                     /locus_tag="ACGI3L_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HFG9196631.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            21937..23316
                     /gene="glmU"
                     /locus_tag="ACGI3L_000905"
     CDS             21937..23316
                     /gene="glmU"
                     /locus_tag="ACGI3L_000905"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFG9196632.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            23411..24361
                     /locus_tag="ACGI3L_000906"
     CDS             23411..24361
                     /locus_tag="ACGI3L_000906"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0002189 - ribose phosphate
                     diphosphokinase complex [Evidence IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFG9196633.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      25199..25284
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            25446..25967
                     /locus_tag="ACGI3L_000907"
     CDS             25446..25967
                     /locus_tag="ACGI3L_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HFG9196634.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNTEGVTLTEAQSAKLLSDIGENKIYTSATTNSLGNPLTSNTKIDNNVLY
                     IVLIDNTVMDTTK"
     gene            26118..27794
                     /locus_tag="ACGI3L_000908"
     CDS             26118..27794
                     /locus_tag="ACGI3L_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HFG9196635.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            27806..29014
                     /locus_tag="ACGI3L_000909"
     CDS             27806..29014
                     /locus_tag="ACGI3L_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HFG9196636.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            29029..30741
                     /locus_tag="ACGI3L_000910"
     CDS             29029..30741
                     /locus_tag="ACGI3L_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HFG9196637.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            30734..31642
                     /gene="pilO"
                     /locus_tag="ACGI3L_000911"
     CDS             30734..31642
                     /gene="pilO"
                     /locus_tag="ACGI3L_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HFG9196638.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            31669..32235
                     /locus_tag="ACGI3L_000912"
     CDS             31669..32235
                     /locus_tag="ACGI3L_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFG9196639.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            32272..32799
                     /locus_tag="ACGI3L_000913"
     CDS             32272..32799
                     /locus_tag="ACGI3L_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFG9196640.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            32820..34358
                     /locus_tag="ACGI3L_000914"
     CDS             32820..34358
                     /locus_tag="ACGI3L_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196641.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRDISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            34458..35540
                     /locus_tag="ACGI3L_000915"
     CDS             34458..35540
                     /locus_tag="ACGI3L_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HFG9196642.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            35521..36303
                     /locus_tag="ACGI3L_000916"
     CDS             35521..36303
                     /locus_tag="ACGI3L_000916"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFG9196643.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            36585..37055
                     /locus_tag="ACGI3L_000917"
     CDS             36585..37055
                     /locus_tag="ACGI3L_000917"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: protein motif:HMM:NF013632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HFG9196644.1"
                     /translation="MVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNIVQ
                     FDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFILA
                     FLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            37069..37629
                     /gene="pth"
                     /locus_tag="ACGI3L_000918"
     CDS             37069..37629
                     /gene="pth"
                     /locus_tag="ACGI3L_000918"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFG9196645.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            37646..41032
                     /gene="mfd"
                     /locus_tag="ACGI3L_000919"
     CDS             37646..41032
                     /gene="mfd"
                     /locus_tag="ACGI3L_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFG9196646.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            41063..42058
                     /locus_tag="ACGI3L_000920"
     CDS             41063..42058
                     /locus_tag="ACGI3L_000920"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9196647.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            42182..42721
                     /gene="spoVT"
                     /locus_tag="ACGI3L_000921"
     CDS             42182..42721
                     /gene="spoVT"
                     /locus_tag="ACGI3L_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HFG9196648.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            42841..44454
                     /locus_tag="ACGI3L_000922"
     CDS             42841..44454
                     /locus_tag="ACGI3L_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFG9196649.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            44561..46009
                     /gene="mazG"
                     /locus_tag="ACGI3L_000923"
     CDS             44561..46009
                     /gene="mazG"
                     /locus_tag="ACGI3L_000923"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HFG9196650.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            46098..46376
                     /locus_tag="ACGI3L_000924"
     CDS             46098..46376
                     /locus_tag="ACGI3L_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFG9196651.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            46448..46690
                     /locus_tag="ACGI3L_000925"
     CDS             46448..46690
                     /locus_tag="ACGI3L_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFG9196652.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            46752..47006
                     /locus_tag="ACGI3L_000926"
     CDS             46752..47006
                     /locus_tag="ACGI3L_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HFG9196653.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            47007..47540
                     /gene="yabQ"
                     /locus_tag="ACGI3L_000927"
     CDS             47007..47540
                     /gene="yabQ"
                     /locus_tag="ACGI3L_000927"
                     /inference="COORDINATES: protein motif:HMM:TIGR02893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0034301 - endospore formation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex biosynthesis protein YabQ"
                     /protein_id="HFG9196654.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            47546..47830
                     /locus_tag="ACGI3L_000928"
     CDS             47546..47830
                     /locus_tag="ACGI3L_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFG9196655.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            47943..48863
                     /locus_tag="ACGI3L_000929"
     CDS             47943..48863
                     /locus_tag="ACGI3L_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HFG9196656.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDKGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            48953..51325
                     /gene="spoIIE"
                     /locus_tag="ACGI3L_000930"
     CDS             48953..51325
                     /gene="spoIIE"
                     /locus_tag="ACGI3L_000930"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HFG9196657.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            51676..53568
                     /gene="pepF"
                     /locus_tag="ACGI3L_000931"
     CDS             51676..53568
                     /gene="pepF"
                     /locus_tag="ACGI3L_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFG9196658.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            53682..54647
                     /gene="galU"
                     /locus_tag="ACGI3L_000932"
     CDS             53682..54647
                     /gene="galU"
                     /locus_tag="ACGI3L_000932"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFG9196659.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            55147..56751
                     /gene="rho"
                     /locus_tag="ACGI3L_000933"
     CDS             55147..56751
                     /gene="rho"
                     /locus_tag="ACGI3L_000933"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFG9196660.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            56904..57104
                     /gene="rpmE"
                     /locus_tag="ACGI3L_000934"
     CDS             56904..57104
                     /gene="rpmE"
                     /locus_tag="ACGI3L_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HFG9196661.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            57249..58142
                     /locus_tag="ACGI3L_000935"
     CDS             57249..58142
                     /locus_tag="ACGI3L_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HFG9196662.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            58160..59008
                     /gene="prmC"
                     /locus_tag="ACGI3L_000936"
     CDS             58160..59008
                     /gene="prmC"
                     /locus_tag="ACGI3L_000936"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFG9196663.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            59052..60116
                     /gene="prfA"
                     /locus_tag="ACGI3L_000937"
     CDS             59052..60116
                     /gene="prfA"
                     /locus_tag="ACGI3L_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFG9196664.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            60245..60925
                     /locus_tag="ACGI3L_000938"
     CDS             60245..60925
                     /locus_tag="ACGI3L_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFG9196665.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            60954..61994
                     /locus_tag="ACGI3L_000939"
     CDS             60954..61994
                     /locus_tag="ACGI3L_000939"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFG9196666.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            62011..62460
                     /locus_tag="ACGI3L_000940"
     CDS             62011..62460
                     /locus_tag="ACGI3L_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HFG9196667.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            62477..62929
                     /gene="rpiB"
                     /locus_tag="ACGI3L_000941"
     CDS             62477..62929
                     /gene="rpiB"
                     /locus_tag="ACGI3L_000941"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HFG9196668.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            62965..63594
                     /gene="upp"
                     /locus_tag="ACGI3L_000942"
     CDS             62965..63594
                     /gene="upp"
                     /locus_tag="ACGI3L_000942"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011971477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFG9196669.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            63889..64704
                     /gene="yqeB"
                     /locus_tag="ACGI3L_000943"
     CDS             63889..64704
                     /gene="yqeB"
                     /locus_tag="ACGI3L_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent molybdenum cofactor
                     biosynthesis protein YqeB"
                     /protein_id="HFG9196670.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            64930..65367
                     /locus_tag="ACGI3L_000944"
     CDS             64930..65367
                     /locus_tag="ACGI3L_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HFG9196671.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            65552..65779
                     /locus_tag="ACGI3L_000945"
     CDS             65552..65779
                     /locus_tag="ACGI3L_000945"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HFG9196672.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            65784..66170
                     /locus_tag="ACGI3L_000946"
     CDS             65784..66170
                     /locus_tag="ACGI3L_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HFG9196673.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            66173..66877
                     /gene="atpB"
                     /locus_tag="ACGI3L_000947"
     CDS             66173..66877
                     /gene="atpB"
                     /locus_tag="ACGI3L_000947"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_component: GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFG9196674.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            66946..67206
                     /gene="atpE"
                     /locus_tag="ACGI3L_000948"
     CDS             66946..67206
                     /gene="atpE"
                     /locus_tag="ACGI3L_000948"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFG9196675.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            67329..67826
                     /gene="atpF"
                     /locus_tag="ACGI3L_000949"
     CDS             67329..67826
                     /gene="atpF"
                     /locus_tag="ACGI3L_000949"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFG9196676.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            67823..68368
                     /locus_tag="ACGI3L_000950"
     CDS             67823..68368
                     /locus_tag="ACGI3L_000950"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFG9196677.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            68385..69887
                     /gene="atpA"
                     /locus_tag="ACGI3L_000951"
     CDS             68385..69887
                     /gene="atpA"
                     /locus_tag="ACGI3L_000951"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFG9196678.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            69915..70793
                     /gene="atpG"
                     /locus_tag="ACGI3L_000952"
     CDS             69915..70793
                     /gene="atpG"
                     /locus_tag="ACGI3L_000952"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HFG9196679.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            70806..72200
                     /gene="atpD"
                     /locus_tag="ACGI3L_000953"
     CDS             70806..72200
                     /gene="atpD"
                     /locus_tag="ACGI3L_000953"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFG9196680.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            72203..72463
                     /gene="atpC"
                     /locus_tag="ACGI3L_000954"
     CDS             72203..72463
                     /gene="atpC"
                     /locus_tag="ACGI3L_000954"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HFG9196681.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
BASE COUNT        29375 a         7765 c        13424 g        22146 t
ORIGIN      
        1 ctcttttttg tatgaaatca aatatatttt catcatttca acaatgaaaa agaagtttat
       61 catattttga gatagtttgt ttttatttat ttaattcata ttttaaaata tattttctta
      121 acattgttaa aaaagaattt acaagagatt cattagaatt aactcaactc taatattcac
      181 ttaacttaag ttgtttatta tattattaaa gagaagtaaa cgaaaggtag attaaggagg
      241 ttgaattttg tatacagttg atagtactaa gatattgata aatatgaact tagagaaact
      301 agaaaagata tactcaatga taaaagatac atcaagtatt tctataatta aagaacctaa
      361 cttggctaca gtaatggtaa gagctaatga aagtgtaaaa aacacaacat ttaatttagg
      421 agagatatta gttactgaat gtagtgtaaa ggtagatgaa agcttgggtt acggaatagt
      481 ttcagaaaac aataataaga aagccattta tttagcagtt atagatgcag ttttacatag
      541 caataacagt aaatttgatg agttaaagaa ttacataaat aaaagtgtat atgaagagaa
      601 cttaaggtat gaacaagaga ttattgatga atttagcttg attaataaaa cgaaagttca
      661 attcaatgct atggattaaa taggaggaga atcatggtaa attatacaca agaaatatat
      721 agaaagatgc tagatagtgc ttcatttcct gggaaattaa ataatataga taatataaat
      781 atagaaaata atacaaatct attgaatgga gcaattggta tagcaatcac tttattagac
      841 caagaagtta ccttctatat agaaaattat actcaaaaag atataaaaaa tataagagca
      901 cttacaatgt caaatcaaat agattataga aaatcagatt atatattttt agatattaat
      961 tcagaagtgg atatattaca gattaaaata ggttcttttg aatatcctga tgaaagtgca
     1021 actatagtac atcaagtaaa tgatttatca acgtactctc aaactaagta tataaagctt
     1081 gatttgagtg gtcctggtat aaaatctaaa aatagtatat atataaatgg aattagagaa
     1141 gaatttatag aaagattatc tagtataaat aaagattatc caataggaat agatttgatt
     1201 ttagtagata aaaaaggaga aattgcattt ataccaaggt catcaaaatt aagttgggag
     1261 gtattataga aatggcttat gtagcagtta aaggtggaga agaagccata ttacaggcta
     1321 aaaatatact tgagttttat agggtaaaag gagatagctt gcctatagat gtaaagcaga
     1381 ttgaggaaca aatgtcttat gctgtagaca aagtaatgtc tgaaggaagt ttatacaaca
     1441 aggaactatc agcattggct ataaaacaag ctcaaggtga tatattagaa gcctctttct
     1501 atgtaagagc tttaaggtca acaatgccta gaattacata ttcagaaccc ataaatacag
     1561 aagaaatgag aataaaaaga agaatatcag ctacttttaa agatatacca ggaggtcagt
     1621 atcttggggc aactagagac tatgaaaata gaatattgaa tgtagaatta ttagaagaag
     1681 atgaaaaaaa gaatagacat tttagagata gttttataaa tgaattagaa acagtagatg
     1741 aaatccctga atttacaaaa atatctaata tatttagaaa agaaaattta ttacaagaag
     1801 aagtttgtga aaacaaattg gaagaagtta ttgatgatat tacaagaaat agtttaagat
     1861 ttccagtttc tagggcagca aagttacagg cattaactag aggtgaaagc ggagtagtat
     1921 caggttttgc ttatgctatt gtaagaggct ttggtgatga acatccatat ataagtgaac
     1981 ttagaactgg caatgtgttt ataaaaataa aacatcccat ctatgaagat gaagaaataa
     2041 caataggtga tatgttggtt actgaatgtg aaatagtttc aaaagcatcg caaaataaga
     2101 ctgaaaattc taaaaataat tcggaagata aaaataaaat gtctttagga tatggtcttt
     2161 gtatggggaa caatgagaat aaggctatat ctatggctat actagacaaa tctttggagc
     2221 caaatagtga aaaactagca caagacgaag aatttgtatt gcttcatata gatggaatag
     2281 attcattagg atttatatct cactttaagc ttcctcacta tgtagatttt aaagcggatg
     2341 tagaaagaat aaaaaagttt gaggaggtaa gtttaggtga tatataacta tggtttttta
     2401 gacgaaaaca caaaaaaaga aataagaaga aagatattaa aagcaatatc aatacctggt
     2461 tatcaagttc cctttggttc aagagagttg cctatagcta agggatgggg tactggaggt
     2521 ttacaattaa cactatcatt aattggtaaa aatgatgtag taaaagtaat tgaccaagga
     2581 agtgatgatt ctacaaatgc ttgtaatata aggagcttta ttgcaagtgt aagtaatgta
     2641 gaaaccacaa aagatacatt agaagctaca ttgattcaaa cgagacatag aataccagaa
     2701 gaaaaactta aatctaatca aatactaata tttcaagtac caataccaga aacccttaga
     2761 atagtagaac ctagtgaagt agaaacaaga agaatgcatt cagaagaaga ttatagtagg
     2821 atgtgggtat atctttatga agatatagtt agatttaatg atatatctat agcagttgaa
     2881 tatccatgta aagtaaatga tagatattta atgaatccat cacctatacc tagatttgat
     2941 ataaaaaaat taaatatgtc agacaattta ttcttgtttg gtgcaggtag agaaaaaaga
     3001 atttatgcta ttcctccata tacaaaggta gaacctttag agtttgagga ttataagttt
     3061 gaagaggaaa agtttgaagg aaaatactgt agtttatgta acagtacaaa tacattttta
     3121 gatgaagtat atgacagtga cactaatgaa aagtactata gttgctcaga tacaagttat
     3181 tgtgaaaaag ttagattaaa aaataacagt atagatgtga caataggagg tacttggaat
     3241 gagtaaaata aatgactcta aaagattaga aaatatagac aagcaagtat taataggaag
     3301 aaatatcaat cttatttatg gagatgggtg tgaaaagtgt tttgaaagca caggatatga
     3361 aagcaataat atatgtaagt attgtggttc tatagttgca tgtaataatg taaatttaga
     3421 actttatgaa ggagaagtcc ttggaattgt aggtgaatct ggttcaggaa aaagcacttt
     3481 attaaaaata ctgtttttcc aagaacatgc aaatagtgga gaagtatata tatcccatta
     3541 caataaagac acaaatatac tagagctttc agaccaaaaa aagagataca taaagaatca
     3601 ttttatgggt attgtgtatc aaaatcccca ccttggttta aatttagact ttagtagtgg
     3661 tggtaatata gcagaaaaat tattgatggc aaatttatat aatgttgaaa aaataagaga
     3721 tagaggcaaa gaacttttaa taaaaactaa tatacctgta gaaagaatag accataaacc
     3781 aaaatacttt agtgggggaa tgcaacaacg agttcaaata gcaaaagctc tttcaaataa
     3841 ccctccaata ttgctattag atgaggttac aacaggttta gatgtttctg tgcaagcgga
     3901 agtattggat ttaataagag aaatccaaag agaatttaag atttctatga tagttgtatc
     3961 ccatgacttt gatgttataa agatgcttgc tgataggaca attgtaatga aaaatggaag
     4021 tgtaattgag tctggtctta cagaccaaat aatggaggac ccacaacacc catatactca
     4081 gcaacttata aattcattgc tataaatatc gtttgtaaat aagcaaaatg ggggttttta
     4141 ataaaatgaa agaaactata cttgaagtaa ataattttag taaagacttt gagttacatg
     4201 cattgaacaa gactataacg gcatgtagta atataagttt tgaagtttca aaaggtgagt
     4261 ttttaggaat aataggtaaa tctggagcag gtaagtctac catattaaaa agtatctata
     4321 aaacatatat accaacaact ggagaaataa tttttaattc agaaatatat ggtaatgtag
     4381 acctggctaa aattggagac cgagaaatga taaatcttag aaagaaagaa ataggatatg
     4441 tatcacagtt tttaaagaca cttccacgaa taactgcaat tgaactggta gtacattctt
     4501 taattgagag tgggtttgaa aaggattgtt cgtatgatat ggcaaaagat atacttaacc
     4561 aatttgaaat aaaggaaaat ttatgggatg cgtatccaaa taatttttct ggtggagaaa
     4621 aattaagatt aaatttagct caagctatgg ttaaaaagcc tagacttttg ttacttgatg
     4681 aaccaactgc atcacttgat aatcaatcta aaatatatgt aaaagaaaaa atgttggagc
     4741 ttaaaagtca aggaactaca atgataggaa tttttcatga tatagagttt atggaaactg
     4801 ttatagataa gacctttact atgacaaaag ggactataag tgaaagtggg gtagcctaga
     4861 tgataaaact aattcataat gcaaatattg tattagaaga tatgatttta gaaaatggtc
     4921 atttaatcat agagggagat acaataaaaa aagtatcaaa tgataagatt gattacgcat
     4981 ttgactttaa tgagatagat gaaataatag atgcaaaaaa cttatatgta atacctggta
     5041 ttatagatat tcacagtgat gccattgaaa aggaaataga gccgagacca agtacattat
     5101 taccatttaa tatggcattt tatgaactag ataaaaaact acctgcaaat ggaataacta
     5161 cagtttatca ttctatatct ttaggggatg gagtaggagt tagaagtatt gataactctt
     5221 taaagatgat taaaaatatt gattcatata aaaatataga tagtaagagc ataaatcata
     5281 aagttcattt aagatatgaa gtgttgtatt atgaaggttt agaaaaggtt ttagaactat
     5341 tagatgaaaa taaaatagac tacttatcaa taatggacca ttctccagga caaggtcagt
     5401 atacaaatcc aacattttat aaagagtatg ctactaaagt gtggggagtt acagaaaatt
     5461 atgtagatac atggttagat gatttagtaa atctgcatga taatttagat tggaataaaa
     5521 tagctaatat tataggtata gccaaaacta aaaatataaa tgttgcatca catgatgatg
     5581 atacattaga aaaaatggat ttcataaaaa atataggcat aaatgtatct gaatttccta
     5641 taactcttga agttgcaaaa cattcaaaga aattgggtgt tctaacttgt ttaggtgcac
     5701 cgaatattgt aagaggtaaa tctcataata acaatttaaa agcaatggat gctatattgg
     5761 aagattgttg tgacattgtg tgttcggatt atcttccatc agctatgata aagtctatgt
     5821 gtatagttgc agaaagaata aataatttaa ataaagcagt cagtttattt acctcaaatc
     5881 ctgctaaagc agttggtata tatgatgaaa gaggtagtat aaaagaaaat aaaaaagcag
     5941 atttagtttt agtagatatt gatagtgaat atccaaaggt tgtaaatact attgtaaatg
     6001 gaaaaacagt ttataaaagg gaggtataaa gattgctaac agagttacat tgtcatacaa
     6061 gtatatcaga taataatttt actactgaag aaataataaa aaaagcagca gaaaagaata
     6121 taaatatctt agcaataaca aatcatgaca cattatctgg attggatgaa gctcttgtgc
     6181 ttggagagca ttatggaata acaataatac caggtataga aatttcagcc tatgattata
     6241 aaaatagaaa aagagttcat attcttggat ataacataga tttaaacagt caagaaataa
     6301 aaaatttgtg caatccaatg gtatgtgaca gacataaagc atctgttaag atggtaaata
     6361 aaattataga tttaggatac aaaatatctt tggaagatgt aaagaaatat tcatcaaaga
     6421 ctggaatatt taaacaacat ataatgaaag ctcttataga taaaggatat acagataata
     6481 tatattcaag tctatataaa gaattgtttc atagaggaaa cggcaaggta tatgtatctt
     6541 taaaatatgt ggattacaga gatgcaataa aagctataaa aaattctggt ggaatttgtg
     6601 tgttagctca cccgggtcaa atggataatt ttagcgctat tgaagagatg gtaaaagtag
     6661 gattagatgg aatagaagta tatcatccat ctcacaacaa agaactagaa aaagagtcgc
     6721 tttcttatgc taagaagtat aatctagtgg tcacaggagg ctcagattac cacggatttt
     6781 attctcaaca taattatgaa cttggaagca agagcttaaa taaagaagat ttatttaagt
     6841 ttaggttagc tttaggaggg gtattataaa tgtctttttt acaagtaaaa aatgtaggta
     6901 aaagttatgg acaagttaag gtgttaaaag acatatctat tgatattgaa aaaggagagt
     6961 ttatttgttt actaggtcca agtggttgtg gaaaaagtac actgcttaga ataattgcag
     7021 ggcttgagga taaacatggt ggaaaaataa taataaatga taaggatatg actaattcac
     7081 cacctgaaag tagaaatttt ggtatagttt ttcaatcata tgcattattt ccaaatatga
     7141 atgtttacaa aaacatagcc tttggactag aaaataaaaa cataagtaaa tctaatattg
     7201 ataaaaaagt taaagaagtt ctagaagttg tagaattaag tggatatgag aaaaaatatc
     7261 catcacaatt atcaggtgga caacaacaaa gggttgcatt agctcgtgcg attgctttag
     7321 agccagactt tttacttctt gatgaacctt tatctgcatt agatgcaaaa gtaagactta
     7381 aacttaggga gcagattaga agtttgcata gaaaactagg cattacaact ataatggtaa
     7441 cgcatgacca agaagaagct ctttgtttag ctgataagat ggttgttatg aatagaggag
     7501 aaataataca agttggaacg ccaaaggagg tatataaaaa tccagaaaca ccttttgtag
     7561 ctgattttat aggaacaata aattttatag atgatggtat taataagata gctattagac
     7621 cagaagatat aaaagtagag tctaatagag attctaaaga taaggatata aaagtgggag
     7681 aaattttaga tatcgaattt agaggattta actatagaat tacagttgag tatcgttcta
     7741 agcagatgaa attagatgta gtttccaaag ttgcagaaca aatgaaactg tgtataggtt
     7801 ctaaaataaa ctttaagata cctaaagaag gaattgtaca atataaatca gagggatgtg
     7861 cttaatagct aggggtgaat aaatgataac atcaaaaaat aaaagaagaa taagtgatag
     7921 cacaatacaa aaatatttct tgattttttc ggtaattgta ctaatagtat ttatattatt
     7981 tccattagta tcattattaa aaaatgcatt tatggataca agtggaaatt ttataggaat
     8041 ttcaaacttt agtaaatatg ttgaaaatcc aagtcttata gcatcattta aaaattcaat
     8101 ttttgtatct acagtctcat ctttaatatc actatgttta gcatttatat attcatacgc
     8161 aataacaaga acaaacataa agtttaaaga attttttaaa actatgggaa tgtttccact
     8221 ttttgcacca actatgttat atggtatttc acttatatac ctttttggaa ataagggaat
     8281 ctttacaacc atgggtctgg aagtaccact atatggtcca ttaggaataa ttatttctca
     8341 gattctattt acatttccac aagctttttt aatattatct gtagcacttt cgatggctga
     8401 ttacagactt tatgaagcag cagatagctt gggtgctagt gaatttaaga aattttgcaa
     8461 aataacaatt cctggtataa agtactcatt acttagttca ttctttgtat cctttatact
     8521 tgcatttaca gattttggag cagctaaggt agttggagga aactacaatg tactggctac
     8581 tgacatatat aaacaagtag ttggacaatt taacatacca atgggagcta ctgtttctat
     8641 ggtaatgtta attcctgtac taatagcatt tacattagat aagatggcaa gtaagaaaca
     8701 aggtatgacc ataactgcaa agtctatgcc atataagatt aaggaaaata agtttagaga
     8761 tagagtattt ttaatagtat gtagttttat aacattgcta atttttattt taatattcgt
     8821 ttcagttata ggttcagtta taaagttatg gccatataat ttaagcttta caatggaaca
     8881 ctatacattt aaaggtattt tgggaagtgg aataaaaaca tatttaagca gtttgaaaat
     8941 atcaacttta acagcaatat ttggaactat atttgtattt tttagtgctt atatgataga
     9001 aaaggtggat aagtttccta aattaagaca aacagcttac cttttatcaa tgataccaat
     9061 ggccttacct ggcttagttt taggtatatc atatataact ttttttaact cagcaagtaa
     9121 tccattaaat tttttatatg gaagtacagc aatattagtt atagtaaatg tagttcattt
     9181 ttattcagtt tgttttataa cctcaaattc atctttaaaa atgttggata aagagtatga
     9241 attagttgca aaatccataa atattccatt ctataaagta ttttttaata taacagttcc
     9301 aatgtctata acatcaatac ttgaaatagt agtatattat tttgtaaatt caatggttac
     9361 tgtttcagca ttaatatttt tatatacacc tcaaactcag actgcatcaa tatcaatact
     9421 aaagttagat gagataggat atataggacc atcagctgct atggcagtat tagtgctttt
     9481 aacaaatata atagtaagac ttttgtacga atttgtaaca aagaaattaa aaaataacac
     9541 acaaaaatgg cagcaaaaag atgttgcata ggggaggtaa aaatgaaatt taagaagcta
     9601 gtttctttag gagtattatc aacactttta ttaagtgtaa taacaggatg tagtactgat
     9661 tcatcaggtt cagattcaaa gtctgatagt aagacaaaag gggatttaac agtttacaca
     9721 gcaattgaag aagatagtat agagccatat ttagctacat ttaaagagaa atatccagat
     9781 attaaattaa atattgttag ggcatcaaca ggagatataa cagcaagatt attagcagaa
     9841 aaggataatc ctcaagcaga tgttgtatgg ggagttgcag ccacaagctt attggttgca
     9901 gatgaccagg ggatgttaga accatatgct ccaaaaggtt ctgaagaaat agagtctgca
     9961 tttaaagatg ataaagaagt tccttcttgg gttgggatag atgcttggat gacaggtata
    10021 acagtaaaca ctaaagaatt aagtgataag aacatcccag ttcctagttc ttacgaagat
    10081 ttaataaagc cagaatataa aggtcttata tctatgccta atccatcttc ttctggtaca
    10141 gggtacttaa cagtatcagc ccttatacaa attatggggg aagaaaaagc atggcagtat
    10201 atggataagt tacatgagaa tattggtgta tacactcaat ctggttcagc tccagctaca
    10261 tcagcagctt caggagaata tcctattggt atatcttttg gatatagagg tataaagtta
    10321 aaagaggaag gctatccagt agaagtagta tttccaaaag aaggttctgg atgggatata
    10381 gaagcaaatg ctcttgtgaa aaaagataat ataaaagaag catcaaaagt atttttagat
    10441 tgggctataa gtaaagatgc aatgaacgaa tactctaaaa actatgcagt tactactatt
    10501 tctacaggaa atccaatacc agaaggattc cctaaaaagc cattagagca aatgatagat
    10561 aatgatttaa aatcagcagc aaaaaataga gaagatatac taaataaatg gatatcaaaa
    10621 tatgatggta agacagaaaa agagagttaa gtaaaactat acaaatggag taaaaagaaa
    10681 aatttttttt aagtagattt tattattata atataagttg agaataatat aggtcaagaa
    10741 aagtgaatat tctataaaaa tgtatagagt aagtatacca ttcagtttga atggtatatt
    10801 ttttattttt agagattaat ttagaaatag atatactaca gtttaaaata gtatatttta
    10861 atttcattat taaagtatag atgttatata taaagtaaat aagatattaa ataattataa
    10921 actaaagtaa ataaaatatt gagcgattat taaaaagata tatatataat ttaatttgag
    10981 cagtttgtta tatattataa aaaaagagaa aaataaaagg taaattgttt ctggataact
    11041 taaaattgga agtaagaata tttaactaga gaagaattat ttaagtttag gttagctcta
    11101 ggagtagctg attttatagg aacaatagat tttatggatg atgatataaa catggtagca
    11161 attagaccag aagatataag ggtagaattt aatagagatt tcaaagaaat tatagacctc
    11221 aaactcagac cgtatcgata taaaaactaa agttagatga tatagtgttg tagataggac
    11281 catcagctgt tatggcagta ttagtgcttt taacaaatat aatagtaaaa cttttgtatg
    11341 aattgataat aaaaaaatta aaaaccaaga cataaaaatg gcaacaaaaa gaagttgaat
    11401 aagggaggta aaaatgaaat ttaagaagtt agtctctttg ggaatattat caacactttt
    11461 attgagtgta ataactggat gtagtaatgt ttcatcaggt tcaaacttaa agtctaataa
    11521 taagacaaaa ggagagttaa cagtttatac agcaattgag gaagatagta tagatacata
    11581 cttagctaca tttaaagaga aatatccaga tattaaattg aatgtactta gattatcagt
    11641 aggaggtata acagcaagat tattagcaga aaaagataat cctaaagcag atgtgttatg
    11701 gggtgttgca gctacaagtt tgataatttt agatgacaaa gaaatgctag agccatacgc
    11761 tccgaaaggc tttgataagg taaattctgc atttaaagat gataagaaag ttccttcttg
    11821 ggttggaata gatgcttgga tgactggtat aacagtaaat actaaagaat taaaagctaa
    11881 aaatatatca gctcctagtt cttatgaaga tttaataaag ccagaatata aagatcttat
    11941 atctatgcct agtccagctt cttcaggaac aggatattta acagtatcag aactcataca
    12001 aattatgggt gaagaaaaag catggcagta tatggataaa ttgcataaaa atattggtgt
    12061 atacactcag tctggttcag ctccagctat attagcagct tcaggagaat atcccattgg
    12121 tatatctttt ggaaatagag gtataaagtt aaaaggtgaa ggttatccag tagaagtagt
    12181 atttccaaaa gaaggttctg gatgggagat agaatcaaat gcacttgtga aaaaagataa
    12241 tataaaagaa gcatcaaaag tatttttaga ttgggctata agtaaagatg caatgaatga
    12301 gtattctaag aattttgcag ttactacaat tgacacggga aatccggtgc cagaaggatt
    12361 tccaaagaat ccattagaac agatgataga taatgattta aaatcagcag caagaaatag
    12421 agaggctata ctaaataaat ggatagaaaa atatgatgga aagacagaaa aagagagcta
    12481 agccttgcaa taaaatttag tacaaaaagc gcctagaata taagttttat atctaggctc
    12541 ttttgatata tttatttaaa atgcatattt ctatataaaa ataaatagtt tagtaccttg
    12601 attaaattaa ataaaaacct taaaataaag agatgtaaag aaaaactaaa aacgaataaa
    12661 aggtgaattt atatgataaa agaaataata gtagtagagg gtagagatga cgttacagca
    12721 gttaagagag caatagatgc agaacttata actacaggtg gatttggatt tccaaaaggt
    12781 gtaatggagc gtataaaagc tgctaatgaa agacgtggtg ttataatatt tacagaccca
    12841 gattttgcag gtgaaaaaat aagaaaaaaa atagcatcag aagttccagg atgtaaacat
    12901 gcatttctac cgagagagga agctaaaaag gatggagata taggtattga gaatgctact
    12961 cctcaaagta taatagcagc tctgaataaa gttagaactg aaaatacaga aaaaagagat
    13021 gaatttaagc aagttgactt aattagaaat ggtcttatag gtaatgaaga agcatcactt
    13081 agaagagatg cacttggaaa aatacttgga attggatatg gaaatgcaaa acaattttta
    13141 aatagattga ataattatgg agttgaaaga gaagaattta tagatgcatt aaaacaaatc
    13201 taaacgtaat gtttaatgta tgaaaaatat gtatataaaa taaattgtgg aattacggtt
    13261 aatttaagat gaattattta taatatacac cttattttaa atcaatgtaa atacatataa
    13321 ataagtataa ttaataaaat taaatatcaa aataagttaa aaaggagtaa ataatggata
    13381 gactatcttc acataatgca acaaaggaag tagtacaaaa atataatttt aaattttcaa
    13441 agtctttagg tcaaaatttc ttgatagata gtaatataat tgataaaatc ttatctggag
    13501 ctagaatcac aagaggagat aatatcatag aagtaggacc tggtatagga actcttactc
    13561 gtgagatggg taaaatagca gaaaaagtag tggctataga aatcgataga aatttaattc
    13621 ctatattgaa agataccttg tcagatttag ataatacaga ggttgtaaat caagatatac
    13681 taaaagtaga catacaggaa ttagtaaaag ataaattaaa tggtgggcca gttaagcttg
    13741 tagcaaatct tccatattat ataactactc caatagttat gaaattttta gaggaagaca
    13801 tacctgtaac agacatagta gtcatggttc aaaaagaagt tgcagataga atgaatgcta
    13861 ttccgggtac taaagattat ggggcattat ctatagctgt tcaatactat tgtgatacag
    13921 agattgtggc aaaagctcca agacatatgt ttataccaca accaaatgta gattccacag
    13981 ttataggtct acatgtaaga gataaaagaa aatatgatgt tcataatgaa gacatatttt
    14041 ttaaaacagt aaaagcatcc tttggacaaa gaagaaaaac tcttcttaat tcgttgggag
    14101 gtcttggttt tcttaataaa gatgaaataa gagaagtatt aaaagaagct aatatagacg
    14161 aaaaaagaag gggtgaaact cttagtatag aagagttttc agttctttca aatataataa
    14221 atacaaaagt atcttctaaa tagaaggtac tttttttaat tttgttaaca tatattgttt
    14281 agagaaactg tgttaagggg ggattgcagt gggttctaaa agaaagttta aaagagacta
    14341 tataatacta gaagctaaag acataaactt tagatacaaa gaacgagtac tgccaaaagc
    14401 ttttgcaaaa gttgaagtaa atgatgaaaa agcaattatt gcattatatg tagaaaatct
    14461 aaaatatgtt aaagatgggt ataaagcagt agcaataaaa gatgaccatg gattaataga
    14521 cttaggaaat ataattttaa atgaacaagg aagaggtgaa tttgttttag atttagaaga
    14581 ttatgatgat gagataaaag gtattgcatt attgtatgaa agaaatatac ctttaattgg
    14641 atttaaagga aataagcttg aaaattatga ggacatatta tttcaagagg tagaggaaga
    14701 agaatatgaa gaatatgaag agttggaaga agaagacgaa gagatagagg agaatgagga
    14761 aagtgataga gacgaagata gtgaagaaga atatattata gaagaatatg atgaagatga
    14821 gtatgaagac tattgggaag atgatgaaga tattgaagaa ggagagttaa aagcaagaac
    14881 ggaagtagaa gattctgatg atgaggaaat agaagagttc aataattata aggaaataga
    14941 aaattataat agggttaaag tacaggaaga atatatagac atagaatatg atgaagaaga
    15001 agaggaagaa gaagtttttg aagtaaatag agaagaagat aggtttgttt cctcaaaacc
    15061 tactaaatca aagaaagttc aaaaagatca gaataatatt gaaaaaataa aaagagctaa
    15121 tggagtaagt caaggagaga gtggaaataa acaaaccagt acattactta tgccaagaca
    15181 aataaaaaaa ggtttgaaat tatttaaaga agtaaaacct tttgtaacag attatataga
    15241 taagacaaga tggtggaaaa tagagataaa tcctacaaca ctgtgtggat atacaatgcc
    15301 ttatttagga tatttaaacg tattgaatta cactatgtat agtgatgcag ttttacattc
    15361 atataaatac agacactatt tatttggagt tcagtatgat gaatataata agagaaaaca
    15421 ttatatttat gctatcccag gaaatagaaa tgaacagcca gacaatggaa gcacaggatt
    15481 tttaagatat caagcttgtg ataatagaac aaatagttta ggatattggc tatgttttat
    15541 agattctaga caaagaaata tagttaggta aaaataataa aaatgaaaaa atttagactc
    15601 aattcttatt ttactgaaaa aattaatgaa atgtagtaca aaactttaaa aactattgat
    15661 aatatttaaa tattacacta caatatatct tgaaatacct attatattat ggaggaaaat
    15721 tatgataaac gagcaaagaa ttttaaatga gtttcttgaa ttagtacaga tagatagttt
    15781 atctttaaaa gaggggaatg ttgctaaagt attagttaaa aaattagaag aaataggttg
    15841 ttcagtagta atagacaatg ctggtgaaaa agcaaatgga gaaactggta atataatagc
    15901 tacattaaaa ggaaataaag aaggaaagaa aatattattt agttcacata tggatacagt
    15961 aactccaggt ataggggtaa aacctatagt ggatgaagca aatggaataa taaaaagtga
    16021 tggtactaca atattaggtt ctgatgataa agcaggtata gcagctatat tagaaggctt
    16081 aagatatata aatgaaaata acatagaaca tactgatata caagttgtat tctctatatg
    16141 tgaggaatgt ggattagttg gagctaaaaa tttagactat ggaaaaatag attctgaata
    16201 tgcatttata ttagatagtg gtggttctcc aggtgaaata atagtaaaag ctcctgcaca
    16261 agatgtaata aatgttaaga tattaggaaa gactgctcat gcaggtcttg aacctgaagc
    16321 tggaataagt gctataatgg tagctgccag agcaatagaa aatatgaatt tacttagaat
    16381 agacgaagaa acaactgcta acataggaat tataaacggt ggaacagcta caaatatagt
    16441 aacaggagaa gttaatatag ttgcagaagc cagaagtcta aaagaaaata aattagatgt
    16501 tcaaactaaa cacatggtag agacttttga aaaagctgcg aaagattttg gagctcaaat
    16561 tgagatagat gttaatagag catacacacc aatagatgtt agtgaggatt ctgaaataat
    16621 aaaacttgca aagaaggctt tttcaaactt aggtatagaa ggtcatactg aatctacagg
    16681 aggaggtagt gatacaaata tattaagtaa gaatggtatc gaagctataa ctttaggaat
    16741 tggtatgaaa aatgctcata cactaagtga acatatagct ataaaagact tatatgattc
    16801 tgctaaaatg gtagtggaga taataaagga agcataaatt taaataatag tgtataatat
    16861 atatatcgcc tagcttaagc taggtgattt ttcattttat agaagattga taatctctat
    16921 tgaaagcaaa gagtatacat ttgcatataa gagagtgttt aatttatgtt caaatgtagg
    16981 ttcttaataa tatttagatt gtttcataag ggaggaataa atatggaaac aaggtatgaa
    17041 gaagcaaata aaataacaat acaatcaata ctttggaata tagtattaac aataattaag
    17101 gttatagctg gtgttattgg taattctagc gctatgattg cggatggatt acattcagca
    17161 tcagatatta taagttctat aggagtacta ataggcaatt atgtatcttc tagacctgga
    17221 gatagagagc ataattatgg tcatgagaaa gcagagacat tagtatcatt tgtgttatca
    17281 atattgctta ttttcgtttc tataacaata ggtatagagg caattaaatc tttatttaac
    17341 ttagatgcat taagtgttcc atcaatatta ccattagtag tatcagttat ttcaatcctg
    17401 ataaaagagt atcaatatag aataacaata aaagttgcta aaaagataaa ttcaccagcc
    17461 ctaaaagctg atgcttggca tcacaggtca gatgctttat cttcagtagc tgcttttata
    17521 ggtataggtg gttctatttt agggtttaaa ccattagacc caattgcgtc agttgtagtg
    17581 gctatatttg tagctaaagt aggaattagt atacttataa gttctgttaa tgaattgatg
    17641 gatgtttcag ttgatgaaga agagataaaa gaattaaaat ttattgtagc agatacagaa
    17701 ggtgttaaaa atcttggtga tataaagact agaaaacatg gagctatggc atatgtagat
    17761 ttgactatat gtgtggatga aaatttgaca gttaagcaag gtcatgatat tgctaccaag
    17821 cttgaaaaac atataataaa acatatggaa tttgtaaaag gtataacagt tcacgttgaa
    17881 ccatgtacta attgccaagg aaataagtgt aataattaat taaaacttaa aaaaaagtgt
    17941 aaaaagttat ataattgttt tatgattata aactctaggg gtggttaaat gagcaagaaa
    18001 agaaaactaa agaaaaaagc tgcaatatta ataggagtag ttgttttctt tataatatac
    18061 tttatatcct ttagaatagg aataaatatg gaaaaggata aaagtgaagt gccaaagaag
    18121 gtagaaaaag aagaagaaga taataggtct ttaaggactc aaataaaaga gaagaagaag
    18181 gtttatatat cagataaaaa tatagaaaac ataaaaattg aagaagatat gtgggatgaa
    18241 ataaagttat ttttctcaga ttttaagaaa gtaagaaata ctacttcttc ttacgaagca
    18301 gtttatgaag gttattctga tgatggagtt aaattttcta ctgaccttaa cttttttaga
    18361 gtatatactg taaataaaga agaatattat aaagtaccag ttagttctaa ggatgctttt
    18421 aagaaacttt tagatgagag tatatatact tcgtttgacc ttttaagtca ttataaagat
    18481 tggaaagagg ttactataac tcatggaaaa gaaattaaaa aagttcatag atggaaattt
    18541 gatgatttag cacataagat gatttcaaag agggttgtag gaaaagttca acctgagaaa
    18601 agtaaggaaa gaagtgacta taattttact ataaatataa aaggtgataa ttttgatgta
    18661 aaagttgata caatgggaaa agattatgta aaagttactt ctaagaaaaa tgtatcttac
    18721 tatgaggttc atacaagttt atttgattac cttaaaaatg agatatttga aattggaaag
    18781 aaataagact ttaagaaggc tatcaaatta gatatttgat agcctaaatt attttatata
    18841 ttatttttca accaacaagt ctgcaacctt ataaattgga ccagcaccag cagttattac
    18901 taaatcatta tccttaacat tttcacgtaa gtattttact atatcttcaa attcttttat
    18961 atagatggca tctacattgt tttgatataa tttctcaacc aagtccttag aatgtatatc
    19021 tcctgggtct ttttccctag cagcatatat atctgttatg ataactttat cagcagcata
    19081 gaatgcctct gaaaattcac ctaaaagaga ttttgttcta gtataagtat gtggctggaa
    19141 gatacaccat aaagttgatt tttttaattt tttggcagca gctaaagttg cttttaactc
    19201 agttggatga tgtgcataat catctactac taaagcattc ttatagtacc ctttagtttc
    19261 aaatcttctt ccgacacctt tataaatttt tatatttttt cttatagtct ctaagtcaat
    19321 accagaaaca agagctgcca ttatggcaga agaagcattg tatatgttat gaagaccata
    19381 tacagaaagt tcaaattctc ctaaatctct tccttcatat tctattctaa atattccatg
    19441 accactattg tcaaagtgaa tatcttttat tacagcatca ttgtcagaat ctctgccgta
    19501 ttttataata gtagctttaa catcatacaa tatgtcatca atattttcat catcgccatt
    19561 tattatgaaa tagccttctg ggggtaataa ttttccaaat ttgttaaaag aagccttgat
    19621 ttcatctatt ccagagaaat aatcaagatg gtcttcttca acatttaaaa ctatagatat
    19681 ctttgggtta aaattaagga aactatctac atattcacat gcttcagtta taaagtggtt
    19741 ggaattacct atcttaacat taccacctat catacttaag ttaccaccaa ctagtatagt
    19801 tgggtctaag tctgcatatt caaagattgt agataacata gatgttgtag aagtttttcc
    19861 atgtgttcca gaaactgcta tagaattttt atattccctc atgatttggc ctaaaaaagt
    19921 tgctctgttc attaccaatt tatttttttc tttagcagcc acaagttctt cattgtctgg
    19981 atgaactgct gctgtataaa caaccatatt tacatcatct gatatattat cttttttctg
    20041 accaatataa atagttgccc cttggtccct aagtttgtct aataggtatg attcgtttga
    20101 atccgaacct gaaacttgat aacctttatt gatacatatt tcagctaatg cactcatgct
    20161 gataccgcca attcctataa agtgtatatt cataataaaa ccacctttct ttttaattaa
    20221 gtcctacaat atgaactatt tctgtggtat aataatataa tgttcaatat tttataatta
    20281 atatgcatat aatattatat gtattttatt tttgaatata ataaaacata agtaatatta
    20341 taccacaata agaattgtta tgcattagtt agtttaacgt tatataaagg tacttgtagg
    20401 aggaaataat aatgaaattt aaaagaacag agagaattgg agcaatagtt aaaatactgt
    20461 ctgataatcc aaataaaata tatactttaa gttattttac aaatcaattt aatgcagcaa
    20521 aatcaacaat aagtgaagat ttattagttg taaaaaatgt atttgagaag ctacatttag
    20581 gtaaagttat aactatttca ggagcagcag gaggagtaaa atatatacct aaaacttcta
    20641 tagcagaaaa tgcagagttc ttaatggaat tatgcgagag aatatgtgac aagtctagaa
    20701 tactatctgg tggtttttta tacttgattg acctaattta cgaccctaca atagctgcta
    20761 agataggaaa gatattcgca tcaaatattg agtatgtaga tgcagattat gttgtgacaa
    20821 tggaaacaaa aggtatacct atggcactta tgactgcaaa agctatgaat ttacctctag
    20881 ttataataag aaaagatata aaggtatcag aaggtcctac acttagcatg acatatgtga
    20941 gtggaaacag ttctaaagtt gaaagtatga gtttgccaag aaaagctctt aaaccagata
    21001 gtaaagttat aattatagat gatttcatga ggggtggagg tactataaaa ggaatggtag
    21061 accttatgaa tgaatttggt gcagaggtta taggtactgg agtattcata tctacaacga
    21121 atccttcaga aaaaatggta aaagattata tttcattgat tcaattggat gttaatggag
    21181 ataaaatagt agtagaacca aacttaaaga cttttaaaga tgaatataga aatgaagatt
    21241 tagacgaaga agaagattca gaatttgaat ttgagataga tgaagattaa taaaaaaaat
    21301 atttagaaaa atatgtaaaa ataaaaagag gatatcccta gttgttcata gaattattta
    21361 aaaaacagtt tatattaatt tattccagcg ataataattt taatataaat taatttctgt
    21421 caaaatcaaa gggggatatt ttggtatgaa gataactgac gtaagagtaa gaaaattaac
    21481 agaagaaggt aagatgaaat gtatagtttc aataactttc gataatttgt ttgtagtgca
    21541 tgatataaaa gttatagaag gccataatgg gctatttata gcaatgccta gcagaaaagt
    21601 aggcgaagga aatttcagag atatagctca tccaataaat gcagaaatga gacaagtttt
    21661 agaagatgca gttttacaag cgtatcatga agcattagtt caatgggaag tagctgctga
    21721 ataataataa atatataaaa tggagagagc ccgaacattt aggctctttt taaatgtaga
    21781 atttctatta aaatatgtac tttttagtaa aaaagtgcta tattattagt gataatgtat
    21841 atgttgtata caaattgtta gataaatgta ttataatgta tattgattaa gagaataata
    21901 cgaataaaat taaattagat tgaatggagt gtatcaatga actttaaagc tataatcctt
    21961 gctgctggca aaggaacaag aatgaagtct aaatacccaa aagttataca taaagtatgt
    22021 ggaaaagaaa tggttaacca tattatagat gtttcaaaaa aatcaggggt aaaagatact
    22081 gtcgtgattt taggacatga agctgatgta gttaaagaaa agcttgcaga agaaattata
    22141 atagccatgc aaacagaaca acttgggaca ggacatgctg taaagatggc taaagaatat
    22201 attaatgatg aagatacaat agttgtactt tgtggagata ctccacttat aaaagaagag
    22261 acactaaaga gactatttga atatcatata gaaaataaat atcatgctac agttcttaca
    22321 acaagagttg gaaatccaac aggttatggt agaataataa gagataagaa gggtgacctt
    22381 cttaaaatag tggaacaaaa agatgcaaat tcagaagaaa agatgataag tgagataaac
    22441 tctggaattt attgttttaa tggaaagagt cttagagaag cactagattt gctaaataat
    22501 aacaattcac aaggtgaata ttatttaact gatactgcta aaataatgag agataaagga
    22561 ttaaaagttg gtgcatttgc aggttcaact attgaagaac ttatgggcgt taattcaaga
    22621 gtagaattat caaaggcaga agaaattatg agacgaagaa taaatgaatc tcatatggta
    22681 aatggagtaa ctataataga cactaactct acctatatag aatctgatgt tatgataggc
    22741 aatgatacta taatatatcc aggtgttatg ttacaaggaa aaacaaggat aggttcagat
    22801 tgtataattg gaatgaattc atctataaca aattcagaaa taggtgatgg tacagaaata
    22861 aaaaattcaa ctataattga tagtaaggtt ggagaaaatt ctactgttgg gccatatgca
    22921 tacttaagac caaagagtga cttaggaaat aatgtaaaaa taggcgattt tgtagaagta
    22981 aaaaatgcta ttatagaaga tggctcaaaa gcatctcacc tttcttatat aggagatgca
    23041 catgtcggta aaaatgtaaa tattggatgt ggagtagtat ttgtaaacta tgatggtaaa
    23101 aataaattta aatcaatagt aaaagacaat gcgtttatag gttcaaattc taatttagtt
    23161 gcaccagtag ttgtagaaga aaaaggatat atagcaacag gttcaacaat aacacatgat
    23221 gtcccagatg gtgctttggc aatagcaaga gaaagacaag ttatcaaaga aggatgggta
    23281 gaaaaaaaga atcaaaaaga cgaccaaagt aagtaattat gtagtttatt attttggcta
    23341 aaaaatttag ctcgaaatta ttataaatta tattcattag tattttaaaa ttttcaggag
    23401 ggttacataa atgaatacta gcggaagcga gattaaaatt attgcaggta attcatcgaa
    23461 agagttagca caaaaaatag ctgactatat aggtgtatca gtactagatt gtgaagtagg
    23521 tacatttagt gatggtgaaa tatgtgtaaa catgaatgag acagtaagag gttgtgatgt
    23581 gtttgtagtg caatctacta acagcccagt aaatgataac ttaatggagt tattaatctt
    23641 aattgatgcg ttaaagagag catcagcagg tagaataaca gcagttattc cttactatgg
    23701 atatgcaaga caagacagaa aggctaaggc aagagatcca atcactgcta aattagttgc
    23761 aaatttaata actgctgctg gagcagatag agtattaaca atggatttac atgcagctca
    23821 aatacaagga tattttgata taccattaga ccacttacta ggtggaacaa tattagcaaa
    23881 ttattttaat gaaaagaaaa tagaagattt agtagtagta tctcctgact taggaagtgt
    23941 tactagatca agaaaatttg ctaatacttt aaatggagaa gttccaatag ctataataga
    24001 taaaagaaga ccgaaagcta atgtatgtga agttatgaac ttaataggtg atgttaaagg
    24061 taaaaatgtt atactattag acgatatgat agatacagca ggaacaatag ttaatgctgc
    24121 aaatgcactt aaagagtttg gagcaaaaga tgtttatgct tgttgtactc atggtgtgtt
    24181 atcaggtcca gctattgaaa gaattgctaa ttcagaaata agtgagttaa tagttcttga
    24241 tactatacaa cttcctgaag agaaaagaat agataagata aagataaaaa cagtagctcc
    24301 tttatttgga gatgctataa gaatgatatt ctctaatgaa tcagtaagta aattattcta
    24361 atttattgta tttatgagag ttgtttaaaa ggatataaac cttttgagca actctttttt
    24421 gattttatac ttatggaatg ttattttttt cttgttagaa aggtatatat tattgtaaaa
    24481 agagattata gtttaaaatt atgtatattt aagtaaaata aacctaataa agggtatatt
    24541 attcaaaata ttatgaatat aaaaaatatt acaaaaaagt attgaaaaaa ttcagattat
    24601 gtagtattat gtaaatataa ataaagaaag aggtgtttcc aatgggaagg ttagaagatg
    24661 aacccctaat aattaaatga ttcagtcaca atctaaagtg aatataaaaa tctattgaaa
    24721 gtttatttat aagaattgaa aatagtatct attctatctt tagtgtttgt gagagggttc
    24781 tggattatat aagattactg taaagagtaa ttttgcacaa taagcatatc tgtaaatgaa
    24841 gagtttcgtt tatataatga ttgtggctga atcataacta taatagatag aatgtttata
    24901 atagatgatt ttataaaata ctatattgta atagctttta gctttcaaat aaatattagc
    24961 aaaggatgga aatgacaatg ataaaactaa atgataattt ataaatatct ccttacgata
    25021 tataataatt gtagggagat gtttcttttt ttgtatagca taatttttct agaaattctg
    25081 tttcaatatg taaaaagttg gtatatataa atagtataaa cagtgttgct aaaatatggt
    25141 agatattata taatataagt ggatatgtat atacattatg agttatataa tttgaattta
    25201 ataaaataga aacgttgatt tatgttctgt aatgtgggca ccttggagca tattgagtta
    25261 gtggtgcaac cggctatgaa attgtattta tttataaata ctattatttt catagctttt
    25321 tttatttaaa aaatggttat atgttagaaa taaatttggt tagtacgttt aaataatttt
    25381 acttagattt ttaaccagat atattgtaag taagtattaa ttaaaaaatt taagggggaa
    25441 taaaaatgaa gttaaaaaag aataaaaaag gtttcacttt agtggaatta ttggtagtaa
    25501 ttgcaattat aggtatatta gcagtagtgg cagttccagc tttatttagt aatataaaca
    25561 aggctaaggt agcaagtgtt gagtctgatt atagttcagt taagagtgca gcattatctt
    25621 attattcaga tactaataag ataccagtta caccagatgg tcaaactggt ttaagtgttt
    25681 tagagactta tatggagtct ctgcctgata aagctgatat aggtggaaaa tataaattga
    25741 ttaaagttgg taataaattg gtattacaga taggtacaaa tactgaagga gttacattaa
    25801 cagaggcaca atcagcaaag ttattgagtg atataggtga aaataaaata tatacaagcg
    25861 ctacaacaaa tagtttggga aatccattaa caagtaatac aaaaatagat aataacgttc
    25921 tatatatagt acttatagat aatactgtga tggacacaac aaaatagtta aaacaatatt
    25981 tttataaaaa tattgtaaat ttaatgaaaa atataatata aaagacagga agaaaatctt
    26041 cctgtttttt tatactattt tctttaatgt tcaattatga atgatgatat aattgagata
    26101 gtaaaggagt gaaacctgtg gctaaaaaag ttagaatagg agacaaactg gtcgaaaaag
    26161 gatatataac agaagaacag cttaaatggg cactatcaga acaaaaaaac agtggaaaaa
    26221 gactaggaga atttctagta caagaagggc ttatagatag taacttacta ataagtgtat
    26281 taaaagaact cttggatata gaaagtatat ttttagaagg gacagaaata gacactttag
    26341 ctacaaaaat ggttccagaa aatatatgca aaagatatac tgtatttcca tttaaaattg
    26401 atggaaataa aatatgtcta gccatgtcag acccacaaga tagagaagca gttcaagatg
    26461 taaggcgtat gtctggtaaa gacgtagaga tatttatatc aagtacagaa gatataaaca
    26521 aagcaatagg tcatgcttat gcacattcag aaataaataa ggcaatgact gagtacaaca
    26581 aaaatagaac tggtggagta agagaaacag taatacttga agaagatgta aatgctgctc
    26641 caatagtacg attagtaaat aacatactag aaaatgctgt tagaatggaa gcaagtgata
    26701 tacatataga acaaagtgaa aattacatgc gtgttaggtt taggatagat ggaatgttaa
    26761 gagaatatat gaggatgaac tcagcaccat ataaggcagt aatcagccgt atcaagataa
    26821 tgtcagatat aaatatatct gaaaagagaa taccacagga tggtagaatc tatttaaaag
    26881 tagataataa acccatagat tttagggttt ctacaatgcc aactaacagg gatgaaaaga
    26941 tagctatgag agttcttgat aagagtaatt ttatggttag taaagaagta ctaggaatag
    27001 acgaacatgg ctctaagata tatgatgaat tgataaacac tccttatggt cttatattgg
    27061 ttgttggccc tactggaagt ggtaaaacca ctacattgta ttcaatgtta aatcaactaa
    27121 atacagaaaa tagaaatcta ttaacaatag aagaccctat agagtatgaa ttacctggtg
    27181 taaatcaatc tcaaataaat gaaaaggcag ggcttacttt cgccagcgga cttagagctt
    27241 ttatgcgtca agacccagat ataataatgg ttggagagat aagagatact gagacagcag
    27301 aaatagcaat tagagcttct cttacaggac atttagtttt aagtacatta catgcaaata
    27361 cagcagttgg agcaatttca cgtcttttag atatggatgt ggaaagtttt ttaataactt
    27421 catctgtttt aggtgtaata tctcaaagac ttacacgaaa aatatgtgag cattgtaagg
    27481 tttcatatga agcagatatt ggagaaaaaa aggctcttgg tattgatgta aatgaatcag
    27541 taactattta tagaggaaaa ggttgtgaaa ggtgtaataa tactggatat aaaggacgtc
    27601 taggtatatt tgaaatgctt gaaattactc cagaaataaa agagttaata gattcatctg
    27661 caaatcaaag agaaatttta aagatggcta gaaaacaagg tatggttagc ttaaaagagg
    27721 atatagttaa aaaagtttta aatggaaaga caacagtaga agaaatgatt agaataattt
    27781 tgatgactga ttaaaggatg atattatgaa aagttttaaa tacacagtaa taaaagagga
    27841 cggaaaaaag caaactgatg tgattgaagc caacgatttt aatgaagcta gaaatcttct
    27901 tagaaagaga aatcttagag ttattgaaat caaagaaagc aaaaataaaa atataagatt
    27961 atctagtaga aagagaaaaa aagacttagg agctgaccag ataagccact tttgtagaca
    28021 gtttgctatt atagtatctt ctggtataaa tagtatttct ggattagaaa cattagctag
    28081 aaggtcaact aacattacat taagagaaga aattaatcgt atagtggcag aaataaaagt
    28141 aggttctact attgcagatt caatgctttc atcaaaatca aagtttccaa agttacttgg
    28201 tgctatggta gctacaggtg aagctacagg taaattagat gaagtattaa aaagtatggc
    28261 ttcattttat gcaagtgaac acagggttaa acaaaagctt agaaatgctg caacatatcc
    28321 attaatagtt ttgatttctt catttataat gatttttata tttacaacat ttatggtgcc
    28381 taagatgatt aattcaatta caacagtagg agcaactctt ccacttataa caagaattgt
    28441 tatggggttt ggtatgttta tgaagaagtt ttggataata gtacttttag ttattatatt
    28501 atttatctat cagtttaaaa aatatctaaa aacgtcagtt ggaagggctc ataaagatag
    28561 agttataaat aagatacctg ttttaggaaa aggaataaat tgtatggtag ctacacgatt
    28621 ttcaagagca ttgtatctat ttgtatcaac aggataccca ttagttcaag ggcttgatta
    28681 tattatagat agtgtaaata acaccatggc agagaagatt ttagcatcag ctaaagatgg
    28741 aataacaaga ggagaaggct tagcagaaaa tttagagaga tatacgtatt ttgactctgt
    28801 gttggtacag atgatagcta taggggagca gacaggggaa ttagagaata taagtagaca
    28861 gatggcagaa ttttatgagt atgaatccga gatttattta aataggatgg cctcaatgat
    28921 agagcctgtt ttaataattg cagttggtat tatagttgcg atactggttg tatcaatatt
    28981 catgccaatg cttagtatat atgatgccat gtaggaggga aaggacaaat gaacaaggtt
    29041 tatgtatcat attatggcga ttctatttcc atagttgagg gcagatataa acacgataag
    29101 gataagtttt atgtaaaaaa ttttaatgtg ttttcaatag aggatattgc acaagatttt
    29161 tctaaggaaa agtatgctct attgagatac gcattagaaa atgttaagtt aaaatcaaga
    29221 catgtagttt tttgtttaaa tacaagagat gtaattttaa aaccccaaaa acttcctaat
    29281 atggacaaaa aggatttaga cggatttatg aagctagaga tggacgaaat gatggctttg
    29341 gagtcagatg aatatgtatt ttcgtatgaa gtatctagtg aaacacctga taattcagat
    29401 ggcgatgaat caagtttaaa tcttattatt ggagctatac aaaaggaaga ggtaaatgca
    29461 attgtagaga taatgcatga atttgattta gtattagata gaatagatac attatcaaca
    29521 gcttacttaa gaatgcttaa aaatttagac tacaatgata taatggtaac caatataagt
    29581 gacaatagca caattataaa tatatataag aaagatactt tatttattag tgataatata
    29641 cctataaaga taactgctaa agatatggac atgcaattat taaatgtagt agaagaatca
    29701 aaaggtctta tgaattacta ttcgtcaaga aactttggta aggttacgga tactatatta
    29761 atattaggaa aaagatattc caataaatta atttatgaaa cttttagctc tgcattttca
    29821 agctatgttt ctcaaggcct tactgagata atggatatat ctgatatgat aactggagat
    29881 atagatgaag atgatataaa ttcaattgta gagcttttag gaagtatgat agaacctaaa
    29941 gggaaaagag attttgaaaa tataaacttt ttaccaatgg atatacttag aaaacagata
    30001 aaagctaaac aaatgaaaaa catactgaaa attgctccaa tagttatttt gattcttgct
    30061 ataccttatt tatgtttaat tttttcaaat aatttagcaa ataaggaact tgaaaatgtt
    30121 aatggtgaaa taagaaatat tgaatctgca tattatcaga ttggaaatat agaaaaaatg
    30181 atacagagta aaagcgaaga aataaaggta tatgatatgt taattgggaa aaaggtaaag
    30241 tgggaaaatt tattggatga tatagataaa aatactccaa gtaaagttga actaacaagt
    30301 ttatcaacaa cttatcaaaa tcttggaact aataataaag ctgataattc aaaaagtaat
    30361 aagactacaa cagataaatc aagtaacaat gaaacaaaat caagtacgaa aagtgatagt
    30421 aatggagata aaacagataa tgatttaaat gaagataaga ctacaaatgt gtcagaagca
    30481 ttaactggaa atagtgagac taatagtaat aacacagata aagatgataa aactccattg
    30541 tatgataaga taccaaatgt tataaatata gaaggaaatg ctaaagattc ctcttatgta
    30601 ggtcaatttt tatataaatt aaagggatta tactatttca aggatgttaa attacatagc
    30661 ataaaaagta atgcagaaga ttctaactat acatttagta tgacattata cctgaaagaa
    30721 ggtgtattaa ctaatgaata aagatatatt taaaaaagat ataaaagata tatttaaaat
    30781 ggaagttagt ctaaaaggga ttcttataaa ggttataatt ttattagcta ttttatcata
    30841 tggttatttt ggactttacc ctcaatatca gaaatatatt gctacaaaaa attctgtaaa
    30901 acaggctact gaaaaattaa atatatataa agagaaaact gcacttatgc caaaatatga
    30961 aaaacaactt gaagaagttg aaagtgaatt aaaagaaaaa agcaaaaatc ttttatatga
    31021 tatgcaagat ggtctttttt taataggttt agataaaaaa atgaaggctt ataatattga
    31081 cttaaccagt tatgacgttg gaaatgttaa agaatacgaa catttttatg gtatatcaac
    31141 aacaataagt gttagaggtg attatagaaa tgtcaaaaaa ttaatggctt atttagaaga
    31201 acaaaaaaat gttactcaaa tactagatta tacaatgact tcatatatag aaccagaaaa
    31261 agaagaggaa gaaacaacaa acaataagga tttaattaaa aatgtgaaca taaataaaga
    31321 tacaaaaata tactgggtgg aaggcgaaaa taagtggcat ttatataagg attgtccatt
    31381 gataaaagag ggagagattc taaaaaatga caaactttta gataggtcta ctaattatct
    31441 atgtaatact tgtgtactta gagctgcaac agaaaaagaa gcaaaaaaag aagtcgtagc
    31501 tccaaaggca gaaggtgtag tagatgctac atttaaattt ataatgtaca ctaaagagaa
    31561 tactacaatg atacttgata cagataatcc atcttcatgg agaccaggaa aatataatcc
    31621 atttaagtct agtgcgaaat aaagctaagt aagctttaaa gataggtgat gagtttgtac
    31681 aaaaataatg aaaaaggtct tactttatta gaagtaataa tagctgtttt tatactgaca
    31741 atagttttaa gtatttctta taaagtgttc aatggtataa catcagcagt aaaaaagcaa
    31801 cagattatta cagatgctca agtaaatatt aatctaatta ataagtatct aaatagagat
    31861 ttggaaaact gtaaagaact aactaaaact ggttcaggta ataattatga atacaatata
    31921 gagatgccag ataatgttgt aaaatatgaa gtttctatag aaactaaaaa aaatacagag
    31981 gtatattctg taacgagaat ccaaaacaat acaattgata cagaaaatga agttagagaa
    32041 gagataatct ataatcaacc actagttcaa aacaataaag aaatgaagga aacaccattt
    32101 aaaatagaaa agcaaactgg taaatctatt tatactgtaa gtatatacta taatgaatca
    32161 gtgcaagaaa gtcataaaaa tagcaattta aataacaaaa cttatacatt tgatgttatg
    32221 tcaagaatag gataataaga atttattaaa aaataagtag gttgataaaa tatgagtaaa
    32281 aagaatagtg aaagaggatt ttccttaatt gaagtgttag tagctatggc tattatggga
    32341 attgtactat ttgcattttt taatattatc aatactaata acaaagcaaa cactaaaaat
    32401 gacacagata taacttcctt aaactatgtc caaagtgaaa tagaaaatct aagagaaaag
    32461 ataaaaagtg gagaatttga ttttgatagt ttagataaac tagaagatgg aactgtcgta
    32521 tatgaaaaat taatagataa atcaaaaaaa gttgtatatg ataaagttct tagtgaaggt
    32581 gatgtgagct tatatgatac tccatatgaa aagattacaa caataaaaga tgaagatggt
    32641 aatttaatcg acaaaggaaa tattacaaat aagataaaga ctattgtaga agataaaagt
    32701 ggtcagatat ataaaatagc tgtaactggg aaaagcatga atgactattc aagtaaaaaa
    32761 gaggttaaaa ttgtaactga aatatttaaa gataaataat tttacttggg ggtgagattt
    32821 tgaggaagtg gaataaattt aaaagtgaaa gaggggcagc tttagtttta gttttggttg
    32881 tagtagcatt gctttctatt gttggattga tattttcaaa tcagatagct aatagaataa
    32941 aatctacaaa gactactaat gaaggtatac aagcaaagta tttagcagag acatgtgtgg
    33001 aaaatagtat tgataaagca tatgaaaaat tgtatgatga gcttgagaaa atggataatg
    33061 agtttaaaag tgaaaatcaa gaaaaatcca tatctaggtc aaaattaaga gatatatcag
    33121 atgaagattt taataatcaa gatgaggaaa atattgaagc agaaagactt ggatatatga
    33181 ataatataaa tttctattta aataaagctt cttcagactt ggaaaaagct agtatggaat
    33241 tgaaaaagct atatgattta gatatgttgg actatagaga cattgaatat gtagatgcaa
    33301 atattatttc acatagagat tctatcttag aaatttgcaa gaattatact tctggagata
    33361 ttagtaaaat aaatgaatat attctgaaag aagatataga ctcaactaca ttgattgagg
    33421 caaagttagt gaataatgat attcttttaa aaatgttttt agaagaaaat aaaattgaaa
    33481 atgaacattt aaattcagcc ttttcacata cttataaggc attagataac atttctttgg
    33541 cgatgcaaaa tatgattgag tatagacata cgtttcatat agatgagcca aaagtagaag
    33601 tatctaatgg gattccagat tctcaacaat attatgaact aatacaaaat cctataataa
    33661 atagtatgga gtatatctgg aatagtaaat gggatacatt agaaaaacta ttggaaattt
    33721 taccaaatca aactcaagga tttaattctt taagagttca tttgagaaat aatgtaagaa
    33781 aatttgagaa gttaagcgat aatatatcta gtggtaaaaa aaatacagca aaaaatttct
    33841 taaagtataa agagttattg tatgaaatat cagaccaatg taatcaacta aaaagtatgt
    33901 cttatgagaa aatacctgtt aaatatgata acatggcttt gataacaact tttgactata
    33961 tacaaaatga gcttttagca gagataaaat gcagattaaa agaattaaaa ccacaagaaa
    34021 ttgataaaac agaaggtatt actataaaaa taccttttta taaggctgac tacgacatga
    34081 caaaagaagg atggcctaaa ttaaaagaaa atggttcagg ggcggagtta agcttaatgg
    34141 taactggtga taaagatgga ataaaagaag tagaagttac agatggtaaa aaaaatatta
    34201 ttggtttagg tgttgaagaa aattcaaatt caaagtataa ggttgacgcc attgtaaact
    34261 ttaatctaaa tatagataca aatgtagttg gaaattatga tataaaagat aaaattttga
    34321 ttaatcatga tataagttca tacaaaaaag taaactaaat ataagaagca acttagtata
    34381 aataaataat aaaataattt tattatttac tactaaaaaa ataagtaaac taatagaaga
    34441 tatggagagt aaatattatg tatatttatg atttattaga gcaaggtata agactaaacg
    34501 catcagatat acacataaca gttggaacaa atcctgtagc tagagtaaaa ggtggatttg
    34561 taaaactaag tgaacaaata ttgacatcag aagtaacaat gcaaatggca aaagacatag
    34621 caggggaatc tatgtttaaa gtaatagaag aacatggaga agctgatttt tcagcttctt
    34681 taaaaacagg agaaagattt agggtaaatg catataggca aaaaggaaat tacgcaatag
    34741 caataaggac tataacagca gaaattccaa catttgaaaa attaggcctt ccagagagta
    34801 taaaatcttt tactgaaaag cataaaggat tagttttagt tacaggtcca acaggaagtg
    34861 gtaaaagtac aacacttgca agtatgataa atataataaa tgaaaaacaa caaaaacata
    34921 taattacact tgaagacccg atagaatatg tacatcatca taaacaaagt ttagtaaatc
    34981 aaagagaagt aggaactgat acagaaagtt ttcattcagc ccttagagct attttgcgtc
    35041 aggacccaga tgtaatacta ataggagaga tgagagaccc tgaaactgtt tcaatagcat
    35101 taacagcagc agaaacaggt catttagtat tttcaacact acatacagtg ggggcagcta
    35161 agacaattga tagaatagta gacatgtttc aaccatccca acagcaacaa ataaaaacac
    35221 agttatctac agtttgtgaa ggtgtggtat cacagcagtt acttcctaca gcagatggga
    35281 aaggcagaat agcagcaatt gaattgatgt ttgctactcc agcaataaaa aacctgataa
    35341 gggaaggcaa aacatatcaa attccaaaca tgatacaaac tggagttaaa gtaggtatga
    35401 aaactatgga ccaagattta atggaacttt ataaaaatgg aaagattaca aaagatatgg
    35461 cacttagtag gtgtactgac caagagttta tgacaagaat gataggtgga gtaaactaca
    35521 atggatatta taatcgttaa tctatatgta tttatggtgg gtatagtgtt tggaagtttc
    35581 tttaacgtct gtatttttag gattccagaa ggtatatcta tttctagacc tccttctcat
    35641 tgtatgagtt gtaatactag actaaagcca atagacttaa taccagtgtt aagctattta
    35701 atgagtggca gaaagtgtag atattgttat gagaaaattt ctagtagata tgctatagtg
    35761 gaattaatta caggactttt atttttaaca gtatttatgt tatatggaat atctacatca
    35821 actatttatt atttggttct tgtgtcttta ctgattataa ttacatttat agatattgac
    35881 cactttataa taccagataa aatattggtt tttggagcta tattttctat gatttttaac
    35941 cttttattta aagaaattcc agttaaggat tcaattctag gtgtttttat ttgtggagga
    36001 agtgtctgga ttatagttct tttgattgaa tttgtaataa aaaaagagtg tatgggtgga
    36061 ggagatatca aactatttgc aatgctaggt ttttacatgg gtgttaaaaa tggtcttttg
    36121 acagccttac taagcgttta tgtgggagca gtctatggaa tctgtgtaat aattataagt
    36181 agaataaaag gaaaggaata taattctgtt ataccatatg gaccttttat atctattgga
    36241 gcattaataa caatcttatg tggaaagcaa ttacttgaac tttatttttc tatggttata
    36301 tagatgatag tcaagttaaa taaagtttta atttaaaaaa atgaattaaa gtatttaata
    36361 aggacaatat tattattaac cctattacta aagtgctaca aactatggag tatataataa
    36421 taatttcctt attttttgca catttgataa ataaatctct atgtgttttt tgtgatagag
    36481 aaaagaaaaa tttatacaat acgtttttta tttacataat aactgtagtt ttatctgtat
    36541 taatatatct aaaatttggg attagtgtag aatgtgtaca atatatggtt ttaattccat
    36601 ttttaataat tatatccatt gtagattact acacaatata tgtatatgat ataacaatag
    36661 ttagtggtat aatagttcaa ggtataattt ttttggtctt tttcaatata gttcaatttg
    36721 attatataaa tcatatattt ggactattga taggctttat tataccttat attattgcta
    36781 aactaacaaa aggattaggc tatggagatg taggtctcta tagcttatgt tgctttgcat
    36841 tgggaaataa ttatgggttt tatgtgatag ttttatcatt tattttagcg tttttgtttt
    36901 ttattatttt atacataact aaaatattta aagatgtaga tataagaaag caaattcctt
    36961 ttacaccttt tatttccttg tcaacaattt taataatatt tacagagtat aatatattta
    37021 atttttatta taatttgtta tacaaattta tataacagga ggtaagaaat gtacgtagta
    37081 gtagggttag gtaatccagg aaagaagtat gagaagacta gacataacgt tggatttgat
    37141 gttatagata ttcttgctaa agaatacaat attagtgtta ctaaaataaa gcataaagct
    37201 ttgattggtg aagggagagt aggtactgaa aaagtattat tagttaaacc acaaacttat
    37261 atgaatttaa gtggagaaac attaatagat atatataaat attataaggt tgatttaagt
    37321 aatatagtag tagtatatga tgatatagat ttagaagttg gaaagatacg tataagaaaa
    37381 aaaggaagtg gaggaactca taatggcatg aaatctataa ctaagtgcct aggttcaaat
    37441 gactttccaa gagtgagagt aggtgtatct aaaccagaag ctggtcaaga cttagcagac
    37501 tttgtacttt ctagatttag aaaagaagaa tctgataaca taaatgaagc attagaaaaa
    37561 gcggcagatg ctattgactc aataataaga gaaaatatag atatgtctat gaacaaatat
    37621 aatggatagt gagagggaga tttaaatgaa tgatgttttt ttatatcctt tgcaaaattc
    37681 aaaagagtat aaagatataa taaactgtat aaaaaataca aaaggctcat tattggttaa
    37741 tggactttta ccagtacaaa aacctcatat atcgtattct atatttaatg atttatcacg
    37801 acaaatgatt tttataacaa gtagtgattt agaagcaaag aaagtatacg aagatttaag
    37861 tttttatatg gaagataaag ttgaatattt aggttttcaa gatatttatt tttatcactt
    37921 ggatgcaaag gacagaaacg aagaagcgaa gaaattaaaa gtattgttaa aactagcaaa
    37981 taaagaaaaa atcattttag taacttctat tgaggcagtt ttaagaaaat acataccaaa
    38041 acaagttttg ctcgatagtg tatctcatta taaggtggga gatagcttag acttagaaaa
    38101 gttaactgag aaattagttt cattgggata tgaaagagtt tcaaaaatag aggggtttgg
    38161 tcaatttagt ataagaggtg gaattattga tgtattttca cttgaatata caaatccaat
    38221 tcgtatggaa ttatttgatg atgagataga ttccatacga acttttgacg tatattcaca
    38281 aaaatcaatt gataaattgc aacaattctc tataactcca tctagggaat ttatttatcc
    38341 cgaaaaaact acagatgcat tagttaaatt aaaaaaagaa acaactaaaa atactgatga
    38401 aggtacattt caaaatatag attatatatc aagtaagact tattttgaag gtgtagagaa
    38461 ctatatagat tatatttatc cagaagaaaa caaaagtata tttacttatt tagcagatga
    38521 tgcaatagta tttattaatg atataacgag acttaaagaa agatgcgaaa attatataaa
    38581 tgagtttaga gaaaattata aattaaatct tgaaagaggt ctggctatta aaaaccaagg
    38641 taaattgtta tatcactata cagatttaga gtacttagta aaagacaagt ctgtggtatt
    38701 aaactcgcta ttgccaaagt ctataaataa cttttctata aaatctataa taaattttga
    38761 aagtagagaa gttcctacat ttaatggaaa ggtagatttg cttgtagaag aattaaatcg
    38821 gctgaaatat aatggataca aaataatttt agcaacaaat accttagaaa gagcaaataa
    38881 attaggaaaa gatttattgg acaaaggctt agaaacgacc atttctaaag atagagatat
    38941 tgaaattaaa tcttcacaag ttataattgt acctgcacac ataaacagtg gttttcagta
    39001 taaatctata aagtttgttg ttataacaga taacgaaatg ataggtgttt ataaaagagc
    39061 gtctaagact agcaataaaa aagttaaaaa gggaaagaaa atagaatcct ttttagattt
    39121 aagtgttgga gattatgtag tccatgaaaa tagtggtgta ggtagataca caggaattga
    39181 acaaattaca gtcaatgcta ttaaaaaaga ttatatgaaa atagtatatc aaggtggaga
    39241 taatctatat gtgccaatag accagatgga caaagtacaa aaatatattg gtgcagaagt
    39301 agaaaaagtt aagttaaata agcttggaac aaatgagtgg acgaaagcaa aagcaaaagt
    39361 taaaaaagaa attgaagata tgacaaaaga cttgattgag ctttatgcaa aacgtgaaaa
    39421 aatacaaggg tataagtttt caaaagatac accttggcag gcagagtttg aatcgttgtt
    39481 tccatatcaa gaaacagaag accaattaaa ggctatagaa gaaactaaaa aagatatgga
    39541 atcaagtaag gtaatggata ggctagtatg tggagatgtt ggttatggaa aaacagaggt
    39601 agctattaga agtattttta aagcttgtat ggaccaaaaa caagttgctg tattggttcc
    39661 aacaacaata ttggcccaac aacattataa tacattcaaa gagaggtttg aaaattatcc
    39721 tttgagagta gaagttttaa gtaggtttaa aacaccaaaa caacaaaaac agattattga
    39781 agatgctaaa aaaggattag tagatatttt aattggaaca catagaataa tatccaaaga
    39841 tataaattta ccaaacttag gtcttgtagt cattgatgaa gaacaaagat ttggagtaaa
    39901 acataaagaa gctttaaaga aaattaaatc tacagtagat gtacttacac tttcagcaac
    39961 tcctatacca agaacattac atatgtcttt aagtggaata agagacatga gtgttataga
    40021 agaacctcca caagaaagac atcctgtaat aacatatgtt acagagagta aggaaagcgt
    40081 aattcaagat gagatagaga gagaattaag tagaggtgga caggtatttt ttgtatacaa
    40141 tagagttgaa cacattgaag aaatggcaag tatgattcaa aaactcgtac cagatgctag
    40201 agtggctgtt gcacatggaa gaatgacttc taaatcatta gaaaatataa tcctaggatt
    40261 tttaaataaa gattatgatg tactagtctg tactacaata attgaaactg gtatggacat
    40321 atcaaatgca aatacaatga ttatatatga tgcagataaa atgggattgg ctcaacttta
    40381 ccaattgaga ggtagggttg gaagaagttc aagacaagga tatgcatatc ttttgtatga
    40441 aaaagataaa actttaagtg agatagcgga gaagagatta aaagctatca gagaatttac
    40501 agagtttggt tctggtttta aaatagcaat gagagacctt gaaataagag gagcaggaaa
    40561 tattttaggt tctcaacaac atggtcatat ggcagttata ggttatgatt tgtacgttaa
    40621 aatgcttaat gatgcaatta aaaaagtcaa aggtgagcct attgtggagg aaattgatgt
    40681 tgaaatagat ttaagtgtaa atgcatacat tccagataat tatatcaaag atgagttgat
    40741 taaaattgaa atgtataaga aaatagcttc tattgaaaac aaagaagaca tgttggatat
    40801 acaagaagaa cttgaggata gattctctga tatacctaaa ccagtccaga cacttcttac
    40861 aatagcttat ataaaatcgt tatgtaagat attaaaaata gaaaagataa gacaattaaa
    40921 agatgaaata ttattagttc caataacaaa gtatagaact aaacagaaaa taggttataa
    40981 tatagttaca gaattagaag aattattaga aaagatgtgc aaggtaaaat aacttgtaaa
    41041 tttaagaagg gatgttttaa atttgaaaaa agtaataaca ttggtaatag ctatgatttt
    41101 ggtagtatct gtgactgctt gcagttctag taaaggagaa actgtggcaa cagttgaagg
    41161 tacaaagata tcatcagatg aatttaaaaa aactatagct ctttataaag attctatgga
    41221 acaaacttat ggaaaagata tatgggataa ggaagttgaa aagggtgtaa aatacaagga
    41281 caagtttaaa gatttaattc ttgaccaact tataactaca gaagtaatat attctcaagc
    41341 taaaaaagat aacttacttc ctaaaaaaga ggatgttgaa aaaagtttta aagaattaaa
    41401 agacgctatg ggtaaagatg aaaaatataa agaacaactt aagaaattag gtatagatga
    41461 tgagttttta agagaccaac aagagaaaga tttagcaatg caaaactatc aaagtaactt
    41521 tgctaaaaag actaaaatat cagatgaaga aatgaaaaaa tactatgata cacataaaga
    41581 tgaatttaaa aaagatgagg tagaagcttc tcatatttta ttgaaaacag tagatgataa
    41641 taacaagcca ctttcagata aggaaaaagc tgaagctaag aaaaaggctg aagaggctct
    41701 taaagaagtt aaatcaggtg aggattttgc aaaagtagca aaaaaatatt cacaagatac
    41761 ttcagcaagt gatggtggta aattaggatt cttttcaagg ggtcaaatgg ttgctgaatt
    41821 tgaagatgct gctttttcta tgaaaaaggg tgaagtatct gatttagttg aaactcaata
    41881 tggataccac ataattaaag tgacagacag aataaatgag caaacatcat ttgaagatgc
    41941 taaagaaact ataaaagacc aactgttgaa aaataaatat caagaacaaa tagaaaaatt
    42001 aactaaagaa gctaaggtag aaaaagatga aaaagtaata aataaaatca caatctaaga
    42061 cttaaaaaaa gagtaatatg cttaaaaaag ctatatctgg ataagatata gctttttttg
    42121 tatatttttc ttaacaatgg taaaaataaa cttaaagtaa tttatggagg gattaaaaaa
    42181 tatgaaagca acaggtatag ttagaagaat agatgatctt ggaagggtag ttatcccaaa
    42241 agagataaga aagacattaa gaattagaga aggagaccct ttagagatat tcacagcaaa
    42301 agatggagaa gtcatactta aaaaatactc tccaataggt gaattaaatg aattttcgca
    42361 agaatatgct gaaacattag ctgaagtact aggatatgga gtgttgataa cagacttaga
    42421 ttctataata gctgtgtcta agcttcctaa aaaagattat aaagaaaaaa gtataagtga
    42481 tgagttagaa gcaataataa gtgaaagaac agtaaaatat tcaaaagata aaaacatttt
    42541 accattattc aaggaagacc aaaaagaata tactagtcaa gttatcatgc ctataattag
    42601 tgcatctggt gactgtatag gttcaattgt agttgtttca aaggataaag atacaattgc
    42661 agaaagtgaa gaaaaatctt taaaaattgc tgctaacttt ttaggaaaac aagttcaata
    42721 attttatcat aaagaccttt tacatgaagg tcttttgaag tttttgtgta aaatattgaa
    42781 tatagcatta aaaatatggt atattaaagt ttgttatata aacagtatgg aggttatgtt
    42841 atgaacaata acaaaaataa agactccttt ctaaaaggag cccttatact tgggctagca
    42901 ggtgtaatcg taaaaataat gggtggattt tttaggattc cccttggaaa catgattggt
    42961 tcagaaggaa tgggatacta tcaggctgct tatcctgtgt atactctatt tttaacatta
    43021 gctactgctg gatttccaac agctgtggca aaattggttt cggaaaaagt tgcaattgga
    43081 aattttaaag gtgcaaataa gatatttaag gtatcacata cagttttatt cattaccggt
    43141 ataatatcat tttgtatatt attttttgga gccgactaca tagtaacaaa cgtaatgaaa
    43201 aatccaggtg cgttatactc tatgaaagcc attgctccag cattactatt tgttcctgca
    43261 atgtctgcat atagaggata ttttcaaggg agacaagata tgactaagat tgctgtgtct
    43321 caagttgcag agcaattttt tagagttgta ttaggtctta ctttggctta cttgcttatg
    43381 aagagtctag gtcagacttt tggtgcagca ggtgctatat caggggctac aataggttca
    43441 atagcatcta tgctttattt ggtgtttgct tatatgctag ggagaaaaga gcgtagagca
    43501 gagatagatg caagccaaag atttaaagat gaaagagtgt cttatatttt taaaaagctt
    43561 ttaactgttg ccattcctat aacaatagga gcatcagtaa tgccacttgt aaatatgata
    43621 gataatgtta ttgtaataag aagacttatg gaagcaggct ttacatacaa agtggcaaat
    43681 tccatgtttg gtcaattaac aggtatggca atggccacaa taaatttacc agcagtcata
    43741 acaactgcaa tgagtatgag cttagttcca gcaatttcta aagcatatgc attaggaaat
    43801 aagtcaaaag ctagaaaaga tactaagagt gcagttaagg taactttact tatagtattg
    43861 ccttgtgcgt ttggtatggc ttctttagca ataccaataa tgggtctttt atttccacat
    43921 gaaccatctt ctgtaggaac tattttgttt actcttactc catgtgtatt atttttagga
    43981 ttaatacaga cattgactgg tataattcag ggaatgggaa aaccaatagt acctgtaatt
    44041 gctttatgtg ttggtatgct atgtaaaatt gtaataagtt atactttaac aggtatacca
    44101 gatattaatg tactgggttc agcatttggt acagttacag catactttgt ggcagccatg
    44161 attaacttac tatatgttaa aaaacacatg aatgtaaact tttctaaaaa agaatttata
    44221 ataaagccat ttataacagt tatgacaatg tttataatgg ttaagttgag ttatggtgct
    44281 ttagttggat tcttaggaaa cagcatatct acaataattg caatatgtgt tggtggaatt
    44341 gtatatgtag tagtaatact tggaataggt ggaattaaaa aagaagagat tctaactatg
    44401 ccaaaaggtg ataaattata taaattgtta aaaaaagtta aacttataag ataatatagg
    44461 aatatatatg caaataaagg aaatactata caaatagtaa atctccttat ttgtataata
    44521 atataaaaat aaagtgaaat ttgctaatag gagtgatgtt atgggtaaga taagtattgt
    44581 aggtcttgga ccaggagact attctcttat aagccaaggt gtgttagaat ctttaataaa
    44641 tagccctaaa gtttttttta gaacagagaa acatccaata attgataaac ttaaagaaac
    44701 tatacaatac acttctttag actactttta tgaaaaagag gaaaattttg ataatgttta
    44761 tttgaaaata tctgaattta tcatagaaga atcagcaaag ggtgacctag tgtatgctgt
    44821 tcctggtcat ccaagagttg cagagaagac tgtaagtata atagagagat tagccaatga
    44881 aaagcacata gcagtagaaa tattgccttc tatgagcttt gtagacgcta tgtttaacta
    44941 tttggctata gacccatctg agggatttaa actggtagat gcttttgaaa tagaaaattc
    45001 atatatagac ttggatacaa gtatgataat aactcaggta tatgataaat ttatagcatc
    45061 taatgtaaag ttaaaactta tggaacatta tgactataat caagaagtat gtatagtaaa
    45121 tggagctggt gtcaaagatt tagaaagtaa aaagtttata aagctttgtg aattagacag
    45181 aaatgaaaac ttttttgact atttaactag cttatatata cccaaaagtt ctaaaaagat
    45241 gtataataca gtacatgact tagaaataat agttaataca cttagaagtc catctggatg
    45301 tgaatgggat aaaaaacaaa cacatcaatc attaaaaaat tctgttatag aggaagcata
    45361 tgaactttgt aatgcaattg ataataatga tatagatgaa atggtagaag agttaggtga
    45421 tgttctttta caggttatat tccattgtca gataggaaat gaggagggct actttgattt
    45481 aaaagaagta gtaaatggca tatgtaaaaa attaattcat agacatcctc atatatttag
    45541 tggtgcaaaa ttagatatgt ctaagtttga gaaaacttgg gaagaattaa agaaagaaga
    45601 gaaaggcgaa agtactataa cagatggcct tagaaggata ccaaaacatt taccagctct
    45661 tatgaaggct agtaaagttc aacataaagc agcacttgtc ggctttgatt gggacaatgt
    45721 agaagatgta tttaaaaaaa ttgaagaaga atatcaggaa ttacttgacg aacacagggt
    45781 cgggaatata aaatacataa aggaagagct aggcgattta ttattttcga tagtaaatct
    45841 agctagattt ttagacatag actcaggaga agccttgaac tgtactacag aaaaattcat
    45901 aaatagattt gactttatag aaaagagtgc aatgaacttg aataaaaaat tagaagacat
    45961 gacacttgaa gagatggatg agttttggaa tcaggctaaa aaacaataaa attgtggaag
    46021 gaaatttgtc aaaaatctag aacttttatc acaaagatag aagtctatat tataaacatt
    46081 tttaggaggt aaatatcgtg aataaagctg aattagtatc aaagatggca gaaaaaagtg
    46141 gattaacaaa gaaggaagca gaagctgcgt taaacgcatt tatgagttct gttcaagatg
    46201 cactagtaaa taatgaaaaa gttcaattag ttggatttgg aacatttgag acaagagaaa
    46261 gagctgctag acaaggaaga aatccaagag atccagagca agttatagat ataccagctt
    46321 ctaaagcacc agttttcaaa gctggaaaag gattaaagga tataataaat ggataattag
    46381 aaatcttgtg aaaaagtgtg gataaatttg ccacactttt tctatagaac caaggaaggt
    46441 gataattatg agattagata aatttttaaa agtatctagg attataaaaa gaagaactgt
    46501 tgctaaagat gcatgtgata aagggattgt cactataaat ggaaaagttg ctaaatcttc
    46561 ttcagaggtg aatattggag atacattaga aatacaattt ggagagaaga agatgaagtt
    46621 taagataaat gaagtaaaag agcatgtatt aaaaaatgat gcaaaagaaa tgtacgaaat
    46681 tttagaataa aattaatagt cctctagtat attaatagta gtattattga aatatttact
    46741 ggggggatat tatggaacag aacataactt tgaaagatag atcaaagctg gttatttcgg
    46801 gagtcgagca catatactct tttaatgaca aaagagtaga gctcaaaact tctgtaggcg
    46861 agatggtaat tgaaggcgaa aacctagata tgagcaagct aagtatagac gaaaatataa
    46921 ttagcataga tggaactata aattctatgg tatatgcaaa gcctaaaaag ccacaagaga
    46981 gtttcttgaa aaaggtattt agatagatga taccttttac tcaagatgta agcatttttt
    47041 atgctactat ttatggtgga atactcatag gggtgttgtt tgatttttat agagggctaa
    47101 gagggaattt taaattcatc aattattttg ctataatatt tgatgtattg ttttggtttc
    47161 tagctacggt tataatattc gtaacaataa accttacaga attttttgat ttaagatatt
    47221 atcattttgt ggctttgttt attggtttta ttttatacta taacaccata agtaaaattg
    47281 ttttatcaat tatcaataaa ataattcgtt ttgtgagaaa ttcttttaaa aaagttacac
    47341 attacatagt cagtttttta aataatttgt attacgttat aatctattca ctacacctac
    47401 tatttgatat tatattttat ataccaaaca tatttatagc aacaagaaaa agtataaaaa
    47461 gaaaatcaaa taaaaaatta aagaacaaga aaaaatcaaa acctaagaag aaaaaaaata
    47521 aaactaaaaa aagggtgtag gaaaaatgaa cttaagaaaa aaattttcag gacagattat
    47581 tgttatcagt ttatttttag gaatatcaat ttttagtatg atgacaggat ttgtatttga
    47641 gtatacaaaa gctaaggaat ataaaaaaga aatagcaagt ctaaataaac aattaaaaaa
    47701 gactgaaata caaataaaca gcttaaagaa agatgaaaaa tcatatgaag gagacttaga
    47761 ggatatagca agaaaaagat tgaatatggt aaaaccaaat gaaacagttt atgtagacat
    47821 aaatcgttga ttaaaacttg ctaataagtt tacagatgta ttgattttaa aatttaagat
    47881 ttaataaaaa agtcattcag ttaaggatgg ctttttgttt ttattgagga gggaatttca
    47941 taatgaaagt aggagctata gatattggga caaactcaat gagattattg atagcagatt
    48001 atagagatgg gaattttata aacagaaaaa aatttgttaa tacaactaga attggttatg
    48061 gtgtggatag taaaggatat ataaaagaag atgctatcaa aagaaatata aaagcattaa
    48121 aagaattttc tgataagtgt aatgatgaaa agtgtgaaaa aatttattgt atggggacat
    48181 ctgctcttag agacagtaaa aatggagatt actttgttaa attagctaaa gaagaaactg
    48241 gaatagatgt tgatatagtt acgggaatag aagaatcaaa tttgggcttt aagggtgttt
    48301 tagaaggaat acaaggtgat gatactatta ttgttataga tattggagga ggttcaacag
    48361 aatttattgt aggtgattca gaaggaatta tatttaataa aagtgagaat gtaggtgctc
    48421 ttaggatgac agagaggttt ttgaagcacg atattattga agatgaagag tttgaagcta
    48481 tgagttcatt tatatatggt gagattgata aaacgttaaa tcatataaaa gacaaaggat
    48541 taaaaactct tataggtata ggaggtacga ttacatcatt atcagcaatg aatcaagaat
    48601 tagagattta ctctatggaa aaaatacata atagtaaaat acacaaaaaa gaaatagaag
    48661 aaattctaca aaaattaata aagatgacat taagtgataa aaagaactta aaagggctac
    48721 aagaaaaacg tgcggatatt ataactgctg gtgtaaaaat attgaatata ataatggaaa
    48781 aattagaaat agaagaaata accgtaagtg aatacgataa tttggaaggc ttaatatgtc
    48841 aaaagtcaaa aaaaatgtat taatattttt tgatttttaa aaccgattat gacaaaaaaa
    48901 attactcctc tttgttacaa ttcttaatat aaacaaaaga ggaggttttt ttatgcaaag
    48961 aagtgtagca gttgtgaaga ataagactgt aaaaccaaat gtcataaaat taataagcgg
    49021 atatattgat tttactacgg cggcattcgc tgtgatggga tttttactta gtaggtctat
    49081 tatagtagac tctgtagctc ctttaggaat tgcctttttt atatgtgcat caaagattga
    49141 taagtacaag atacctgtat tcatatcaac attattagga atattgttat catctaatga
    49201 ttttggaaat gtagcaaaat atgctgtgtg ccttacaata tttatggcta tgaataaaaa
    49261 attaaaatta tcagattcaa ttgctaaggt tgcatttata ggtgcaataa tactacttcc
    49321 aatctccatg ggacaagctt tcttttcaaa taggtatgta tatggtcttc ttatagcagg
    49381 agtagaagca ataataatgt ttatatctat atatgtgttt tcttatggga taggtttaat
    49441 ggccaatgtc aacaatagga tgtctgtacg gacagaagaa gccatatcaa taagtttact
    49501 gctaaccttt agcataatgg gaataggaga tatatctctg tttggaatat caataaggac
    49561 cattttatcg accgtattga tattgctgac ctcaatagta ggtggagcta ctatgggagc
    49621 atctagtggt gtaattattg gtgtagcatc cattttaaat aatatgacat cagctgttta
    49681 tatggggata tattcttttt caggattaat aagtggagca tttaataaaa taaataaata
    49741 tttctgtata ctaggatata ttctaagttg gacaataata tacctatata cttctggtat
    49801 tacttctaat atgatgcaat taagagatat actattaggt tgtttgatag tactagtatt
    49861 gccagagcga ttatttaata agattgaaaa attaataaaa agtaatgtgg cttcaaatga
    49921 aatcgtatac gattatatta tgagaagcaa aaacctaact aatagcagat tgaacagtat
    49981 ttataaaact tatgatgacc ttgcagatac atttgataag ataagagaaa aagacaaagt
    50041 gctagaccaa agagacatag ctaatgtaat agatatgatt cataatgatg aatgtaaaag
    50101 ttgtagtatg agaagaatgt gctgggagtc aagatttaat catacataca ctatgatata
    50161 taacattctt gaaaaaattg aggagaaagg ggagttaagt ctaaacgata tacctaaaaa
    50221 ttttagaaag gaatgtatga aaccagagtc aatagtgaaa atatcaaatc actattacaa
    50281 aatgtttgta ttagattatg attggagtgt gaagttttca gaaagtagaa agttaatagc
    50341 aaatcagata agaagtattt caaaatccat taaatcctta tctcaagatt tagaaggcga
    50401 cataatgcta gatatagaaa aggaaaaaaa tatatatgaa cagttagaaa gatatgatat
    50461 aacagttgat aaagtaagtt acttaacaaa aagtaacagt gagtttgaaa tatcaataga
    50521 aaagaaaact tgccatgatg gatgtatgtg tgaagataaa attgtaaata taatttcaga
    50581 cctagtaggg gaaaatatgt ctgttagaaa aataggatgt cactgtttag gaggtaaatg
    50641 caaggcaaca ttcgttaaat ctcaaaaata taaggctgtt acagaagttt cagcaatgtc
    50701 aagggatggg catatccttt gtggagacaa ttacacatac atggagataa atgatggtaa
    50761 atacatgatg gctataagtg atggtatggg aaaaggtaaa aaagcatatg aagaatcttc
    50821 tgccactatt gatatactgg aaaaaatgat agatgcaaaa attaaagatg agatagtcat
    50881 tgatactata aataatatgt tgttgttaaa gtcttcagaa gagatgtttt caactctgga
    50941 tttgggaatt ttagatttaa aacgaggttg tttagaaact ataaagatgg gagcgtgttc
    51001 tacttatata aaaagagagg atggagaagt tgacttaata tcgtcatcat cattacctgt
    51061 gggtatatta tcagatgtaa aaattgatag aaaaaatgta aaagttaagg aaggagacta
    51121 tgttataatg gtttctgatg gaattgtaga tgcaggaaga aataacaatt taggagacaa
    51181 ttggttaata tacttcttaa agaatataga gactacaaat ccaaaggaaa tttcaaattt
    51241 aatattggat agagcattag agttacaagc gttacaaatt gaagatgaca tgactgtttt
    51301 agttacgaaa atatgtacaa aataaggttt acaagattat gtgtataaga tgtggataac
    51361 ttgtgtataa tatgttaata gacttttgaa aaaagtatag ttattaacaa aaataacata
    51421 taaatcaaca aaatttgttg ataagtatgg cagaaatgtt aataaaatgt aaaaaaagaa
    51481 aaaacaaaag ctattatcaa aagagattca tgttgaaata actaaatttc taagtaaaga
    51541 aaacctgtga atatgttgat tattatgtgg ataactatta attcgatatt tatttatata
    51601 gtatgaataa ttgaataata tatctaaaaa aagccatcct attattaagt aaacttattg
    51661 aaaggatggc tttttatgaa tagaaaattg tgcaaagcaa taataccttt atttatttct
    51721 attttttgca tgttaataat aagtataaaa gctgaccaag gatatcaaaa gaataatgat
    51781 agagcaatta ctgtcatgaa taataatgat actgaagatg atgctgaaaa aaaacaagaa
    51841 atagactatg aaaaaacatg ttggaatttg caatctttgt ttaaaagtga tgaccaatgg
    51901 aaaaaagaac ttaagagttt tgataaagat actaaagagt tgaaaaatta cataggtaaa
    51961 gtaacaaaat cgccaacaca tttgtctttt gccttaaaca ttaaagaaaa acttgatata
    52021 agactaaata aactttctgc ctatgtaaaa ttaaaacaag atactaataa aaattcgtat
    52081 aagtacttag atatgaatga tagtatgagt aaatcctatg ggaattatat ggggatttgt
    52141 tcagatttag agttagaaat actaaaatta tcaaacaaag attacaagaa aattatttca
    52201 aataaaaata taaataggaa atatggtgca tatttaagag atataagaag gaataaagta
    52261 cattatttgg atgataaatc agaagatatt ctaagcaaag tatcttcaat aagtagtctt
    52321 ccaagccaag tatatgaatt atttagaaat atggatagaa aaactaattt gacaccagct
    52381 caatatgcga gtgaattaga gtcatcagat agagaaaata gaaaaaaagc ttatcaagat
    52441 gaacttataa cttacaatga taatataaat acaattgcag gtttaattac tggtcaagtt
    52501 aaaaagaata ttttttattc tcaggaaaga ggttatgagt cttctttaga aatgtacctg
    52561 gaatctgata atgtagatga aaaagtatac aataatttga taaggactgt aaatagtaat
    52621 atggacagtc tacacaaata tatagattta agaaaaaaag tattaaaatt agataaggtt
    52681 cattcatatg atatgtttgt gcctatggtt aaggctgttg ataataatat taattatgaa
    52741 aaggcacaaa gtatagtata ttcagcgttg tcacctttag gaaaagaata caatgatgta
    52801 gtatataaag ctttcaatga aaaatggata gatgtttatt cacatgaaaa taaagtaagt
    52861 ggtggatact gcttatctgt ttatgaaaat catccatata tacttttaaa ttataataat
    52921 tcattaggtt cagtttcgac tttatcacat gagcttggac atgctgtata tgaatattta
    52981 agttctaaga atcagaatta ttttaattca aatccgtcta tatttactca cgaagttgca
    53041 tctacaacga atgaagcatt actttacgag atgcttataa aagaagctaa aggcaatgat
    53101 gaaaaagctt attatataac acagtattta gacttgataa aagatactct ttatacacaa
    53161 actatgtatg ctgaatttga aaaaactata cacgagttag tagaaaaagg aaaaagtgta
    53221 aacgcattag tattaaatga tgtttgggga caacttctta aaaaatatta tggacaaagc
    53281 tatgaattag accaattatc taaggtcgga tgggctagaa tcccacattt ttataatagt
    53341 ttctatgtct ataaatatgc tacaggttgt agtgcaggag taagttttgc ccaagacatc
    53401 ctaaagaatg gttcagataa ctatatgagc tttcttaaaa agggaagttc agattatcca
    53461 ataaacttgt taaaatcaag tggcataaat ttaactaata caaaacccat agaaaataca
    53521 atcaaaaaat ttgatagttt agtagcagaa cttgaaaagc tattataaac attattgtaa
    53581 ttcacatggt aaatatatcg aattaatgat aaaatatact aaaagtttaa agtcctatca
    53641 agataggact ttttatttat taattagtgg gagatgattc tatgcaagtt aaagttaaaa
    53701 aggctgtaat accagcagca ggtttaggaa ctagattttt gccagctaca aaggcacaac
    53761 caaaagagat gttaccaata gttgataagc caactctaca atacataata gaagaagctg
    53821 tggcctcagg aatagaggaa atactaataa taacaggtag aaataaaaaa tctattgaag
    53881 accactttga taaatctgta gaattggaac ttgatttaga gaaaaaaggt aagaaagaat
    53941 tgttggaggt agtacaaaac atatctaaca tgattaacat acattatata agacaaaaag
    54001 agccaaaagg gttgggagat gcaatttatt gtgcgaggca ttttataggt gatgagccgt
    54061 ttgcagtaat gttaggggat gatattgtag ataatgatgt accttgtcta aaacaactaa
    54121 cagatgcata tgaggaatat agaactacaa tattgggtgt tcaaaaggta aatcaagaag
    54181 atactaataa atatgggata atagaagcaa aaaatataga aggtagagtt tacaaggtaa
    54241 aagacatggt agaaaagcca gagtcaggaa aagctccttc aaatattgct attttaggta
    54301 gatatataat aactcctgaa atctttgata ttcttaagga tttaccacca ggtaaaggtg
    54361 gagaggtaca acttacagat gctttaaaaa tattatctaa gaaagaagct atgtatgcat
    54421 acaattttga aggcaagaga tatgatgttg gggacaagct aggattttta gaagctactg
    54481 ttgactttgc tctaaagaaa gaagacctta aggaagattt tataaaatat ttgaaacatg
    54541 tatgtagtga atttgataaa aataacaatg tgttatacaa taatacagat gaaaaaatag
    54601 atttaattga agtcaatgaa gctagagaac ttgaaattca aaaataatta atgaaaggtg
    54661 atgtatggtg gcaaaatcaa gtcagaaaag aattaataga ataatagctg ttgggattgt
    54721 gggaatcctc gtaataacga gtataacagc tgttttgagt atgattgcaa ctatgtaata
    54781 agataaatga cagcagttga tatacataaa tataaaaacc atatataact tgatgtagtc
    54841 aaaaacttac aatattttag ttatatatgg tttttagaat ttataaatgt aaaaaaaaat
    54901 ttttataata gttgcatatt ttaaaggaaa atattattat aagatataaa tatagtgata
    54961 aatttataaa aacgtgctaa gattggactt gaaatacagt aatatagtag gtaataatgt
    55021 tttaaatttt atttattgac cataatatat aaataatgat attattagac ttaactgttt
    55081 aaataaaact tttctttttc atgccttcaa tttccaaaat aagtatgtat ataaatgaat
    55141 atatagatga ggaggatttt tttgatttta gatgataaag tattagaagg attaggtagt
    55201 aagaccttag ttgagctacg agagatagct aaagaattaa aaataaaatc aattactaca
    55261 tataagaaaa atgagttaat tgagattata aattccaaaa gtaaaaatga ggaaaaagta
    55321 aacgaagaga ctaaagaaaa aaatgaagat attaaagaag acataaagaa tagaaaagaa
    55381 aatatagagc gtgaaagtat agaaaaagaa gttgaatata agagccctac caaatcatac
    55441 aacaagaaag aaatagatac ccaaaatatt tcccaaaacc aagaacatag aaatcaaaga
    55501 aatgactata ataagacaac gagtgtaaat gatagtaata agtcatcaaa tatatctaat
    55561 agaatggtca gaaataataa taaaaactat tatatgccta aacaagttga tgaatctaag
    55621 atagtagatg aatttaacac atcaaaagag gatgaagtag taggtgtact tgaaattctg
    55681 ccagatggat ttggtttttt aagaggttca aattatttgt ctactgaagg agatgtttac
    55741 gtttcaccat ctcaaataag aagatttaat atgaaaacag gagacaagat taagggaata
    55801 actagacatc caaaaagtgg agagaaattt agagcacttt tatatgttca aaaaataaat
    55861 gatgaaaacc ctgacacagc tatacaaaga aatgcgtttg agacattaac accaatattt
    55921 ccagaagaac gacttacact ggaaactaat agaaatgaaa tagctacaag aattatagat
    55981 ttaatttcac ctataggaaa aggacaaaga ggattgatag tagcacctcc aaaagctggg
    56041 aaaacagttc ttttaaaaag cgttgcaaat agcatagcta aaaatcatcc aaatgttgaa
    56101 cttatagtac tccttataga tgaaagacca gaggaagtta ctgatatgaa agaatctatt
    56161 gaaggagacg ttatatattc cacttttgac caagtatcaa gtcatcatgt caaggttgca
    56221 gagatggtgt taaatagagc tcaaagatta gttgaacatg gtaaagatgt agtaatttta
    56281 ctagatagta taaccagatt ggcaagggca tataacctta caatatctcc tacaggtaga
    56341 actttatctg gaggtattga ccctggtgca cttcatggac ctaaaaagtt ctttggtgca
    56401 gcaaggaata ttagacaggg tggttctttg acaatattag gaacagcatt ggttgaaact
    56461 ggttctagga tggatgatgt aatatttgag gaatttaaag gtacaggaaa tatggagcta
    56521 catttagata gaaaattagc agaaaaaaga atattccctg caatagatat ttacaagtct
    56581 ggtacaagaa gagatgattt attgcttgat gatgaagaaa agactgctct ttggagatta
    56641 agaagagaaa tgagtaataa ttcagtaatg gaaattacag ataaagtcat tgaacttata
    56701 aagagaacta aggacaataa agagtttgta aaatcaataa agaatttgta aaatcaataa
    56761 tacaaatgca aatatggatt atataaacta atagaaaaat cacttgaatg gcataataag
    56821 ttgtgctata ataatgtagt tgataatgta aaaagaaagt taatataatt aattttttta
    56881 aataaagaga agaggtgact ataatgcaaa aggaaataca accaaaatac aatccagttg
    56941 aagtgcgttg tgcttgtggg aacacatttg ttgctggttc aactaaggac gaaataaaag
    57001 ttgaaatatg ttcagagtgc catccattct atacaggaaa acaaaagaac atagaaaaag
    57061 gtggaagaat cgacaaattc aagaaaagat tcaaaatgga ctaattttta taaaagtgga
    57121 gttggaggaa gccaactcct attttattac aaaaaaacat tcatattcta ctttaaattg
    57181 tctttttgta ttataataat aaatatgtaa aattgagtat tctaaataca ataaaatgag
    57241 gtgagtggat ggcaaaacaa gctgtaggtg ggcaagctgt tattgaaggt gtaatgatgc
    57301 agtcaaaaga caaaagagcg gtagctgtta gaaaaagtga cggagaaata gcactaaaag
    57361 aagatagaat aaaaagttgg gtaagagata agaatataga taagatacct tttgttagag
    57421 gttcttttgt tatgatagat acaatgattc aaggcataaa aagtttaaac ttttcttcag
    57481 agttttttat ggaagaagct gaagaggata aatttgattt atttataaag aaaattttta
    57541 aagataaggc aaatgatata attataatat tttcattggt catagcaatg ttactttctg
    57601 ctggattatt catttttata cctacattgg taggaggagc tttttctaaa gtaatgccta
    57661 atgattttat gcttaattta atagaaggaa tcataaggat agctatatta tttgcatata
    57721 tagtattgat ttcacgaagt aaggatatag aaagagtctt tcaatatcat ggagcagaac
    57781 ataaatctat atattgctat gaaaatgatt tagaacttac agtagagaat gctagaaaat
    57841 ttaaaagatt acatcctaga tgtggtacaa atttcctatt tatagttatg gctgtatcaa
    57901 taatattgtt tgcatttttt ggttggccaa atccaattct tagaatattt atgagaatta
    57961 tatgtgtgcc tatagtagca ggtttatctt atgaggtaat tagagttctt gggaaatatg
    58021 ataatggatt tactaaaatt attgcatatc caggaatgat gttgcaatat tttacaacaa
    58081 aagagcctga tgatgagcaa ttagaggttg ctttggaagc attgaaagca gtagtagatt
    58141 agagaaaagg atatttgtta tgacgataaa agatataatt attaaatatt cagataaact
    58201 aaaagatata agtgatactc caagattaga tacagagtta ttgttacaaa aaacattggg
    58261 tgttgataga ttatatattc acttaaatct gaataaagag ctaactgaag aacaaaaaac
    58321 aaaatttatg ggttttgcag aagaaagatt aaatggaaga ccaatagcat atatagttga
    58381 aaatagggag tttatgggat tagatttttt tgttaaggaa ggcgtattga ttccaagacc
    58441 agatacagaa actttagtag aagaaataat tgaaatatgt agagaaaaaa aagatgtaag
    58501 tatattagat ataggaactg gttctggagc tattacaata agtttagcaa agtacattga
    58561 aaattctaaa atcatgtctt ttgatatatc agagacagca ttagaaatag ctaaaaaaaa
    58621 tgctattata aatgaagttg gtgaaaaaat aaagtatatt aattctgatt tatttacagc
    58681 aataagtgat agtaacataa aattcgatat catagtttca aatccaccat atattaaaaa
    58741 acaagatata gaaactctgc acaaacaagt taaagattat gaaccatata atgctcttga
    58801 aggtggagaa gatggattag acttttatag aagaataaca gaacaaggta agaaatattt
    58861 aaataagtgt ggaatattag catatgaagt tggtcataat caagctgaag atgtaataaa
    58921 tattatgaaa agtaatggat ataaaaaaat atacacaaag aaggatattc aaggcattga
    58981 tagagttgtt ataggttaca atatatgata taatcaacaa ttgatatgtt acatttaatc
    59041 gaggtgaaag tatgttaaaa aaattagagg tattggaaga tacatataaa gacttaagtg
    59101 aaaaaatagg tgatccggat gtaataaatg atcaaaaagt ttggcagaaa tatataaaag
    59161 aacatgctga cttggaacct attgttatga aatacagaga gtataaaagc gttttagata
    59221 gtataaaaga atcaaaagaa attttacaag aagagtcaga tgaagaatta agagaattag
    59281 ctaaaatgga gttagctgag atggaagaaa aagtagcacc tctggaggaa gaaataaaaa
    59341 tactattatt gcctaaagac cctaatgatg ataagaacgt tatagttgaa attagaggtg
    59401 gagctggagg agatgaagca gctctatttg ctggtgattt atttagaatg tactcaaggt
    59461 atgctgaaag aagaagatgg aaaatagaat tattgagtgc aagtgatact ggagttggtg
    59521 gatataaaga agtatctttt atgataaaag gtaaaggtgc ttattcaaga ttaaagtatg
    59581 aatctggagt tcatagagtt caaagaatac catcaactga atctggtgga agaatacaca
    59641 catcaacttc tactgttgca gtattaccag aagttgaaga tgtagaggtt gaaataaatc
    59701 caaatgattt aagaatagat gttttccgtt cttcaggtaa tggaggacaa agtgtcaata
    59761 ctactgactc tgctgttagg gtaacacata tacctacagg tgaagtagta tcttgtcaag
    59821 atggaaaatc acaattaaaa aataaagagc aagctttaaa aatattaaaa gctagacttt
    59881 acgataaagc attggcagaa caacacaaag atatagcagc agaaagaaaa agccaagtcg
    59941 gaacaggaga caggtcagaa agaataagaa catataattt ccctcaaggt agaataagtg
    60001 accatagaat aaatttaact ttatataagt tagatgcatt cttagatgga gatatagatg
    60061 aaatgataga tgctttaatt actgttgacc aaacagaaaa aatgactgca atataagtaa
    60121 tgttttaaag aagctgtttc ttcctagaaa ttattttcta ttttgaaaca gctattttgc
    60181 attttaggtc atgttatcat attctattgt atataattgt tatatacaag tataggaggg
    60241 ttatatgata ctaaaagtaa caataattgg gcttttggca ggtgttatag ggacaggatt
    60301 aggaggagta atatcagcca tttttaaaag agaggtcgat aaatatctaa gtttttttat
    60361 gggattatct ggtggaataa tgttggctgt agtggtgttt gatttaatga aagaatccat
    60421 ggacaaaatg gggataatca atacagttat atttacgttt gttggagctc tcataactat
    60481 gtacataaaa acaaaattag atgtgtctgg aaatatggca tctggatatc ttatattcat
    60541 aagtatatta ctacataatt taccagaagg actagccatt ggttcttctt ttatgtcaac
    60601 tgaaagttta ggtattacac ttgctatagt tataggtcta cataatatac cagaagggtt
    60661 agctatggca ttaggcttag tttgcaataa aatgaaacta agtaaagtta ttttgtttac
    60721 tgtaatagct ggattaccta tgggtctagg aagtttttta ggtgtttatt ttggaggagt
    60781 atttacttct cttataggag tatttcttgc tacagcagga ggtactatga tgtatgttgt
    60841 attggaagaa atttttccac attcaaaaag tgtgtattgt ataattggtt tcttgttagg
    60901 tacaatgatt gtaaattata tataaaatta aaatgaaagc aggcatacaa aagatgaaaa
    60961 ctattataag taatattgat ataaataata ttgattatga ggaaataaaa atacaagcaa
    61021 aacttcttag agaaggtaaa acggttattt ttccaactga gacagtatat gggttgggtg
    61081 caaatgcatt agatgaaaat gcagtaaaga agatttatga agctaaagga agacctagtg
    61141 ataatccatt gatagtccat atatatgaaa aagaagaagt atatgactta gccaaagata
    61201 taagtgataa agctaaactt gttatagaaa agctttggcc aggacctata acaattatat
    61261 taaataaaaa agatataatt ccatacaaaa ctagtggagg gcttgataca gttgcaataa
    61321 ggatgccttc taatgttatt gccagggcaa taataaaaga agctggtata cctattgcag
    61381 ctccttctgc aaatatctca ggtcgcccat ctccaacaaa agcaaaacat gtatatgaag
    61441 agatgaatgg aagagtggat ggaatagttt taggaggaga cagtaatttt ggattggagt
    61501 caactgtatt ggatttaaca gaagagactc ctatgatact gagaccagga agtataacta
    61561 aagaagtttt agaggaactt cttggagaag taaagcttga cccatcatta agtaaaaaag
    61621 aagataatca aaaagctaaa gctcctggaa tgaaatataa acattattct ccaaatgcag
    61681 atgtatatat aatatctgga aaaagagaaa atgtagcaac aaagattaat gatatgataa
    61741 aatctaatag agacaaaggt ctaaagacag gtgtaatgtg tattagtaga aaccgagagt
    61801 tttatgatgg agaagtaatc gatttaggaa actctcttga agaagttgca agtaatctgt
    61861 ttgatgctct tatagaaatg gacaaaaagg gtgttgatgt catatattca gaagagttcc
    61921 ccaagactgg agttggacaa gcaattatga atagactact gaagtcagca ggatacaaag
    61981 tgataaaggc ttaagaggga gttgtaaaat atgaatatac ttattgtgtg tacaggtaat
    62041 acttgtagaa gccctatggc tgaggctata ctaaggaaag caattaaaga atctggaaga
    62101 agtattgaag aatattctat atcatcagca ggtatatcta cagcaaatgg aatgggtgct
    62161 tctgaaaatt ctatagaagt actaaaagaa atcggtatag acttatcaaa tcatagaagt
    62221 aaagtaatta ctaaaaaatt aattgatgaa tcagatataa tactaacaat gactaaatct
    62281 cataaagaaa ttttagtaca agcagttcca aaatgcaaag aaaaagtgta tacttttaaa
    62341 gggtttgcaa ataaaaatga ggaagatata tctgacccat ttggtggaaa tttggatatt
    62401 tatagaagca ctatgagaga aataatgtat tctgtcaacg aaatagtaaa aaaaatatga
    62461 aacggaggat aaacaaatga agataggatt aggctgtgac catggaggat ataatttaaa
    62521 aaaagaaata ataagctatt tagaaagtaa aggtatagag tgtgtagatt atggaactaa
    62581 taatgctaca gattctgttg attatcctgt ttatggagaa atagttgcaa attcagttat
    62641 aaataaagaa gtagattatg gaatattatg ttgtggtaca gggataggaa tatctttagc
    62701 tgctaataag gttcctggga taagatgtgc agttgtatca gatgtatttt ctgcaaaaat
    62761 gtcaaaagca cataatgatg caaatatgtt atcattaggc gaaagagttt taggaaaagg
    62821 tctagcactt gagatagttg aagcatggat taatacggat tttgaaggtg atagacatgc
    62881 tagaagagta aacatgatta aatcaataga agaaaaacat aataaataat aaaaattaca
    62941 gttttatcag gaggaattat caaaatgagc aaagtggtag agacaaacca tccattaata
    63001 caacataaat taactttaat gagagataaa aatactggtt ctaaagactt tagagagctt
    63061 ttaactgaaa ttgcaatgtt aatggggtat gaaataacaa aagatatacc attaaaagat
    63121 gtagaaatag aaactcctat tcaaaaaaca tcatctaaag tagttgcagg taaaaaatta
    63181 gcaataattc caattttaag agcaggtctt ggaatggtag atggattagt gagcttaatg
    63241 ccagcagcaa aagttggaca tgtaggacta tatagagacc cagaaacatt aaaaccagtt
    63301 gaatattatt gtaagcttcc tcaagacata ggagaaagag atataatagt agttgaccct
    63361 atgcttgcaa cagggggttc tgctgtagca gctatagatt tacttaagtc taaaggagct
    63421 aaaagtataa aattagctaa tttagtagct gcaccagaag gtatagcaga agtgcaaaaa
    63481 tatcatgatg atgttgatat atatgttgca tcagttgacg aaagattaaa tgaacatgga
    63541 tatataattc ctggtcttgg tgatgctgga gatagattgt ttggaactaa ataaaaataa
    63601 ataactataa atatttatta gggactttct tatatagtgt atataatttt atgtaagaag
    63661 gttctttttt atatattttt tctcaaaata ggaattattg aattgataaa tttctcgaat
    63721 tgagaataaa aagtttttac caattaaaaa agattgctta ttttacaagg ttttatagaa
    63781 tagtagtcta ttttaatgtg gcatgttagt tgcttacgat tataggtatt aagtgtatta
    63841 gttaaattga gaattgaata ttaataatat tattgggagt ggtaatacat gaagaattgt
    63901 atagtagtaa gaggggctgg agatttagca acagcagtta ttcataaatt acacaacagt
    63961 ggttttaaag tagttgcgtt agaaatagaa gagccattag ctataagaag gcaaatttct
    64021 ttttgtgagg ctgtttatga aaaaaaagta actgttgaag gtgtagaatg tatattttgc
    64081 aatactgaaa aagaaataga ggaagtttta tctcaacata aagtagcctt gattatagac
    64141 ccaaaaggag aaaaattatc taaattaaat ccaatcgttt tggttgatgg aatactcgct
    64201 aagaaaaact taggtacaac taaagatatg gcaccactta caatagcttt aggtcctgga
    64261 ttttgtgcag gagaagatgt agatgttgtt atagagacaa tgagaggtca taatctagga
    64321 agaataataa ctaatggtag agcagaaaaa aatacaggag taccaggagc aataaaaggt
    64381 ttttctaaag agagagttat gcattcacag tatgatggca taatggaaaa tgtatgtaag
    64441 ataggtgata tagttgaaaa gggagaccta ctttgctata ttaataatta tgaaaaaaaa
    64501 catgaagtta gagcaacaat atctggagtc cttagaggtt tattaaagga tggagcaaag
    64561 gtaaacaaaa atttaaaaat actagacata gaccctagaa aagaagaagt taagaatgct
    64621 tttacaatat cagataaagc tagatgtata gctggagggg ttttagaagc catactaaac
    64681 aatgggattt atccccaaaa ttaatttata ttagataaag ctattaatat tttattaaga
    64741 tgatataata aatttaatag attaaagaga gcatatgacg ggtatttaaa atttaaatgg
    64801 taaaaatgct ctttttttat tggacattca attaacatgt gtatataata taaaaataag
    64861 tatttattta ggttgaaatc taataaatat ataataccag tacataagca aagaggagaa
    64921 aagtaaatta tgagaccatc atgggatgaa tacttcatgg aaattgcaga agtagtgaaa
    64981 aagcgttcaa cttgtattag aagacaagta ggagctgtaa ttgtaagaga caaacaaata
    65041 ttaacaactg gatataatgg ttctccgaga aatcttgaac actgtgaaaa tattggatgt
    65101 aagaggcagg aattaaatat tccctcagga gaaaggcatg aattatgtag agcattacat
    65161 gctgaacaaa atgcgataat acaagctgct cataatggta ttagtgtaga tggggcaact
    65221 ttgtatgtta ctacaagacc ttgtgttttg tgtgcaaaaa tgtgcataaa tgcaggtata
    65281 ttgaaaattg tttatgaagg tgattatcca gatgatatgt ctacagaatt attaaaagaa
    65341 gcaggaatag aactcataaa attttagtgg ataaaattta tatgacaata aatgtcaaat
    65401 tatgacactg aaatacaatg gtatcaaatg attaaaagaa agtatttgaa aaatcatcag
    65461 attagtagta agatatattt tataattaaa taaatttatg agatagatta attacatgtt
    65521 atttatttta taataatgag ggatactatt tatgagtaaa agaaatacac atacagaaat
    65581 tgcaaagttg tttagtttaa taagtcaaat aggattgatg attgtaatat caatattagg
    65641 atgtactttc ttaggaaaat ttttagatag taaattgaat actactccag ttctgacaat
    65701 aatattttta ttgttgggtg ttggaggtgc ttttagtggt gtttataaaa ctctaatagt
    65761 atatacacga aggaagtgat atattggata taaaattact taaccaggta aggtcagtaa
    65821 caaaaggtat agtaatattt gatgtagttt taattgtgct aatgttgata acatcaacat
    65881 taagtaaacc agtattatta ggacttatat ttggctctat aatagctatg ttaaatttta
    65941 gattattggc gatatcactg gaaaaatcag tgacatttcc tgctgggaag gcacaagctt
    66001 atgcatcagc acaatatgct gttagattat ttataatggc agttgttcta attgcatcag
    66061 ctacagtacc acatttaaat ataatcggaa cagcattggg attattgagc acaaagtttg
    66121 tcatattatc aaaaaacttt ataaataaat taaagaggaa ggaggcataa gtatgaatca
    66181 agcgcattat tatctcatag gaaactttaa gattagtgaa acaatactag taagttgggg
    66241 aataatggcc tttttagcga tagcatctta ttttttgact agaaacttaa aaaaagttcc
    66301 aactagtaaa gttcaaatat tcttagaatt tgcagtaggt ggtcttgcta aaatggttac
    66361 agatgttatg ggtaaaaata cagtaaaaag aatgccatat atgataccat acataggaag
    66421 cttgttttta tttttcgcat gttcaaattt aagcccatta cttggattaa ggtcaccaac
    66481 aaccgactta gacacaactg ctgcatgggc aatgattaca ttttttatga tttattttgc
    66541 aggagttaaa tttaaggggt tatcatactt taaagaattg gctcaaccac ttgccataat
    66601 gttaccaatc aatattatag gtgagttagc tagaccaata tcattaagtt tccgtccatt
    66661 tgggaatatt ttaggtggaa caataataat gggtctgttt tatcaacttt taggttttat
    66721 atctagttta ataccaggat tatcaatacc aattggagaa atattaatac cagtcccatt
    66781 acacttgtac tttgacttat ttgcaggatt gttacaagca tatatattta taatgttaac
    66841 aatggtattt atatcaagtg caggagagtt agattaagaa atcaacttat attaagataa
    66901 aaataaaata atttaaaaaa ttaaagtttt aaggaggaaa taattatgga aacagcaata
    66961 gtagcggcag catcagcaat aggagcaggg atagcagttg caacaggtat aggtgcaggt
    67021 ataggtcaag gtatagcagc agctaaagct gcagaagcag taggaaacca accagaagct
    67081 aaaggtgata taacatcaac tttattacta ggagttgcta tagcagagtc ttcagcaata
    67141 tatggtttgg ttatatcaat aatacttcta ttcgtaaatc cattctttaa atacttagga
    67201 atgtagattt agtccttaaa tattttgaga taggtttata ggtaaatcat ctcaaactta
    67261 taatcatgag atgaacttta tcatctcgtg attataagta gttatgattt atggaaagga
    67321 ggataattat ggaaaaagca ctagtaggta taacgtggga atttgtgttc caaattgtta
    67381 atacttttat aatattttta cttctgagaa agcttttatt caagccagta ttaaatataa
    67441 ttgaatcaag agaaaatgat attaaaagtg atttggcaga aggcgaaaaa gcaaaaaatg
    67501 aaggtttagc tctgaaaaaa gaatatgagt caaaaatcaa ttttgccaag gatgaaggtc
    67561 aagaaatcat aaaacaagca actataagag cagagcagaa atcagatgat atagtaaata
    67621 ctgcaaagaa agatgctctt gatataaaag aaaaagcaaa caaagatata gaacaagaaa
    67681 gacaaaaggt tataaatgaa atcaaaaatg atatatctaa catagcacta cttgcagcat
    67741 ctaaagtcat tgaaaaagat ttagataaat ctaaacatga agaattgata gaaaacttta
    67801 taaaagaggt aggggaagct aaatgataaa tgtaatagca aatagatatg cagaagccct
    67861 atttcaatta ggagaagaag aaaattcaac tgatgtctta ttcaaagaac tagaaaaagt
    67921 agtagatatg atgactaaag ttagtaaaga tttctacaaa gttttaaaat caccattagt
    67981 ttcaaaatca gaaaagaaaa acttggtaga aattattttt agtaaagaag taagttctaa
    68041 cataaaaaac tttttaaaag ttttagtaga taaagataga atatcatatt tagaagatat
    68101 cgaattagct tataaagaat tattaaataa gaaaaacaat gtaattgatg gagtagcaat
    68161 aagtgctatt ccaatgagtg aaacagatat taaagaactt gaagtcaaac tttcaaataa
    68221 atacaacaaa aatgttacta tagaaaatgt tgttgacaag actatactag ggggagttct
    68281 agttagaatt ggaaatgaac aaatagatgg cactgtgaaa actcgtcttg ataagatgaa
    68341 agaaaagcta tctgaagtaa tatcttaaga atggcggtga acccatgaac ttaaaacctg
    68401 aagaaataag ttctataatt aaacagcaaa taaaaaatta tgagaataaa gttgagttga
    68461 cagatacagg tagtgtttta acagttgggg atggtatagc gagtgtatat ggattagaaa
    68521 aagctatgtc tggtgagttg ctagagttcc caggtgaaat atatggtatg gcacttaact
    68581 tggaagaaga agtagttgga gctgttatcc ttggagatga cagtgaaata aaagaaggcg
    68641 atatagttaa gagaactgga agaatagttg aagttccagt tggagaagct ttaataggta
    68701 gagttgtaaa ctcactaggt cagccaatag atggaaaagg acctatagcg tacacaaaaa
    68761 ctagaccagt tgaatctgag gcacctggta taatagatag aaggtctgtt tatgaaccat
    68821 tacaaacagg aatcaaatca atagattcaa tgataccaat tggtagaggt caaagagagt
    68881 taataatagg tgacagacaa actggtaaaa catctatagt tattgacact atactaaatc
    68941 aaaaaggaaa agatgttatc tgtatatatg tagcaattgg acaaaaacgt tctactatag
    69001 ctcaattagt tagctcttta gaaaaaggtg gagctttgga ttatacaata gtagtttcag
    69061 caacagcatc tgaatcagca ccacttcaat atatagcacc atatgctgga gcagctatgg
    69121 gtgaagaatt tatgtacaat gggaaacatg tacttatagt gtatgatgat ttaagtaaac
    69181 aagctgttgc atatagagaa atgtcattgt tacttagaag accaccagga cgtgaggcat
    69241 atcctggaga tgtattctat ttacattcaa gattacttga aagagcagct aagttatctg
    69301 atgaattggg tggaggttca atgactgcct tgcctataat agaaactcaa gctggtgacg
    69361 tttctgcata tataccaaca aatgttatat ctataacaga tggtcaaata tacttacaac
    69421 cagagttatt ctattcaggt gtaagaccag cagttgaccc tggtatatca gtatcaaggg
    69481 ttggtggttc tgcgcaaatt aaagcaatga aaaaagttgc aggaacatta aaacttgcat
    69541 attcacaata tagagaactt gcagcattct cacagtttgg ttctgactta gatgaagata
    69601 ctaaaaagag acttgctcaa ggtgaaagaa tcgttgagat attaaaacaa ggtgagcatc
    69661 aaccaataaa agttgaaaat caagttatga taatatatgc tgttataaat aatcatttag
    69721 aggatattcc gatagataat atagctagat ttgaatcaga attgtatgca tttgtagata
    69781 ataattatcc ggaaatatca agaaaaatat taggtggaga agacttcact catgatttaa
    69841 cagatgcaat aaatgaattt aaagaaaagt ttgttgttga agtataatcc tttttaaaaa
    69901 aggaggtaaa ttaattggca ggagctggaa tcaaagcaat caaaacacgt atgggaactg
    69961 ttgaaagtac aaagcaaata actaaagcaa tggaattagt tgcatcttct aagcttagaa
    70021 aagcaaaaga aaaggctgaa gattcaagag aatattttaa tactttatac aatacagtaa
    70081 aagatattgc ccaaacaaca cgtggaatta gaaatgaatt tttaaaagaa agagaagtaa
    70141 aaaataaatg ctatgtagta gtagctggag acagaggact tgcaggtgga tacaattcta
    70201 atgtattaaa ggaatctgtc tctcatatga aaggtaaaaa ggaaacagtg attactgttg
    70261 gaaagaaagc acatgaattt ttttctaaaa gaaactacaa tatagcaaaa gatataaata
    70321 gtgttgaagc ttgtggatat gaagatgcga cagaaatttc acaaactatt attgacctgt
    70381 ataaaaaagg tgaagtagat gaagtttata ttgcttatac aaaatttaaa tctgctttat
    70441 cacaagaagt tgaaattttg aaattgcttc cattagtctt tgaaaaagat acagacgaac
    70501 aaggaatggc agtaaaagaa gaaaaacaaa atagatcaaa agtacaatat ataccatcag
    70561 cagaagcagt tttaagttat attgtacctc agtttatatc aggtacagta tatggtggaa
    70621 ttttggaatc ttttgcatca gagcaaggtg ctagaagaac tgcaatggaa tcagccacag
    70681 acaatgcgaa tgaaatgcta tctaatttag agttaagtta taacagagca agacagtcag
    70741 ctgtaactca agaaataaca gagatagttg gtggagttga agctctaaaa tagggaggtt
    70801 aggaaatggc aaatgtaggt aaagtagtac agattgtagg agctgtacta gatgttaagt
    70861 ttgatagtga acaaagccta cctaacttat taaatgcgtt agtaataaag ttaggagata
    70921 aagaaatagt tgcagaagtt gctcaacata taggtgatga tactgtaaga tgtatagcta
    70981 tgagtgcaac agacggactt gtaagaggta tggaagttgt agatacagga gggccaataa
    71041 gtgttcctgt tggagatgaa actttaggta gaatattcaa tgttcttgga aaaccagttg
    71101 atgggaaacc agctccaaaa tctgcaccta aattacctat acatagacca gcaccagcat
    71161 atgatgaact agaaactaca gcagagatac tagaaactgg tattaaggta gttgacttac
    71221 tagctccata tctaaaaggt ggaaaaatag gtctatttgg aggagcagga gtaggaaaga
    71281 cagttctaat acaagagctt ataaacaata ttgctaagca acatggtggt atttctgtgt
    71341 tttcaggagt aggagaaaga acaagagaag gtaacgacct ttatggcgaa atgagtgagt
    71401 ctggagttat aaataaaaca gctctagtat ttggtcaaat gaatgaacca cctggagcga
    71461 gaatgagagt tgctttaact ggacttacaa tggcagaaca ttttagagat gagcaaggac
    71521 aagacgtttt acttttcgtt gataatatat tccgtttcac acaagctggt tcagaagttt
    71581 cagcacttct aggacgtatg ccatcagctg ttggttatca gccaacatta gctactgaaa
    71641 tgggtgcact tcaagagaga ataacatcaa ctaagaaagg ttcaataaca tctgttcaag
    71701 cagtatatgt accagcagat gacttaactg acccagcacc agctacaaca ttctctcact
    71761 tagatgcaaa aacagtttta tcaagacaaa tatcatcact gggtatatat ccagcagttg
    71821 accctcttga atctacatca aggattcttg accctagtat agtaggaaaa gaacattatg
    71881 aagtagctag aggtgtacaa tcaatacttc aaagatataa agaacttcaa gatataattg
    71941 ctatacttgg tatggatgaa ttatctgatg aagataagtt aatagttgca cgtgctagaa
    72001 agatacaaag attcttatct caatcattca cagttgctga gcaatttaca ggaaatccag
    72061 gtcaatatgt tcctgttaaa gagactgtaa gaggatttaa agaaattctt gaagggaaac
    72121 atgatgactt accagagtca gcattcttat ttgtaggaac aatagaagac gctgttagaa
    72181 aagcgaaggg aagtatgtag tcatggccag tgaattttca ttgaaagttg taactccaag
    72241 taatactttt tatgatggag atgttgaaat gatagtagtt agaactacaa aaggagacaa
    72301 aggggtgttg aaaggtcata taccatttgt ttcaggtata cctgtaggaa ctttaaagat
    72361 aaaaaaagag ggaagtttta aagaggcgaa aatagcagaa ggattcatta atgtaactca
    72421 agataaaact gtcatattga cagaatctgc tgagtggatt taataaatta atttagagta
    72481 taaaaagtca ttttgaccaa aaaaactttt gggtaaaatg gcttttttgc gttttggtgt
    72541 taataaaata acgataaaat tgtaagtttt tagtgataat aaattcacaa aatgtttaaa
    72601 tttactgcca aattatgttg taattaataa gataaagaag atttagatag cttttatgta
    72661 agtgaaaaag tcttcatata agaaatacat ataaaatttt tataaaattt
//
LOCUS       DAYAKB010000012        72301 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.012, whole genome shotgun sequence.
ACCESSION   DAYAKB010000012 DAYAKB010000000
VERSION     DAYAKB010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.012"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..264
                     /locus_tag="ACGI3L_000955"
     CDS             <1..264
                     /locus_tag="ACGI3L_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196682.1"
                     /translation="IYNIKKNKEIKENMIAFYLVLLGQIFQIYTITIVIMFTYIYKFV
                     GIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKLIM"
     gene            278..745
                     /locus_tag="ACGI3L_000956"
     CDS             278..745
                     /locus_tag="ACGI3L_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9196683.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            748..1902
                     /locus_tag="ACGI3L_000957"
     CDS             748..1902
                     /locus_tag="ACGI3L_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9196684.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            2218..2970
                     /locus_tag="ACGI3L_000958"
     CDS             2218..2970
                     /locus_tag="ACGI3L_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196685.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            2971..4878
                     /locus_tag="ACGI3L_000959"
     CDS             2971..4878
                     /locus_tag="ACGI3L_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9196686.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAMFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            5030..5710
                     /locus_tag="ACGI3L_000960"
     CDS             5030..5710
                     /locus_tag="ACGI3L_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196687.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GVGYIIQC"
     gene            5704..6723
                     /locus_tag="ACGI3L_000961"
     CDS             5704..6723
                     /locus_tag="ACGI3L_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFG9196688.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLIKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            7163..8314
                     /gene="anmK"
                     /locus_tag="ACGI3L_000962"
     CDS             7163..8314
                     /gene="anmK"
                     /locus_tag="ACGI3L_000962"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase AnmK"
                     /protein_id="HFG9196689.1"
                     /translation="MYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEIPKD
                     IKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHGQTI
                     FHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEFLLY
                     SDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYDKNG
                     YFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDLIAT
                     VTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQDEYG
                     YSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            8316..8714
                     /locus_tag="ACGI3L_000963"
     CDS             8316..8714
                     /locus_tag="ACGI3L_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196690.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            8977..9285
                     /locus_tag="ACGI3L_000964"
     CDS             8977..9285
                     /locus_tag="ACGI3L_000964"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196691.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            9374..10720
                     /locus_tag="ACGI3L_000965"
     CDS             9374..10720
                     /locus_tag="ACGI3L_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFG9196692.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            10953..12050
                     /locus_tag="ACGI3L_000966"
     CDS             10953..12050
                     /locus_tag="ACGI3L_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFG9196693.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            12149..13063
                     /gene="murQ"
                     /locus_tag="ACGI3L_000967"
     CDS             12149..13063
                     /gene="murQ"
                     /locus_tag="ACGI3L_000967"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFG9196694.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            13173..14093
                     /locus_tag="ACGI3L_000968"
     CDS             13173..14093
                     /locus_tag="ACGI3L_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HFG9196695.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIKGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            14110..14961
                     /locus_tag="ACGI3L_000969"
     CDS             14110..14961
                     /locus_tag="ACGI3L_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9196696.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMISSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            15573..16634
                     /locus_tag="ACGI3L_000970"
     CDS             15573..16634
                     /locus_tag="ACGI3L_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HFG9196697.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(16750..17724)
                     /locus_tag="ACGI3L_000971"
     CDS             complement(16750..17724)
                     /locus_tag="ACGI3L_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFG9196698.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            18180..19061
                     /gene="pepI"
                     /locus_tag="ACGI3L_000972"
     CDS             18180..19061
                     /gene="pepI"
                     /locus_tag="ACGI3L_000972"
                     /EC_number="3.4.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase"
                     /protein_id="HFG9196699.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVGGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            19443..20246
                     /locus_tag="ACGI3L_000973"
     CDS             19443..20246
                     /locus_tag="ACGI3L_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196700.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESALKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            20258..21388
                     /locus_tag="ACGI3L_000974"
     CDS             20258..21388
                     /locus_tag="ACGI3L_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9196701.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            21392..22801
                     /locus_tag="ACGI3L_000975"
     CDS             21392..22801
                     /locus_tag="ACGI3L_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFG9196702.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            23018..23521
                     /locus_tag="ACGI3L_000976"
     CDS             23018..23521
                     /locus_tag="ACGI3L_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HFG9196703.1"
                     /translation="MFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPIYS
                     NNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRGGK
                     CEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVSSY
                     ISSHIPQ"
     gene            25428..26783
                     /locus_tag="ACGI3L_000977"
     CDS             25428..26783
                     /locus_tag="ACGI3L_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFG9196704.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
     gene            complement(27009..27890)
                     /locus_tag="ACGI3L_000978"
     CDS             complement(27009..27890)
                     /locus_tag="ACGI3L_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFG9196705.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDTSNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNNITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(27877..28629)
                     /locus_tag="ACGI3L_000979"
     CDS             complement(27877..28629)
                     /locus_tag="ACGI3L_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFG9196706.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            28887..29213
                     /gene="trxA"
                     /locus_tag="ACGI3L_000980"
     CDS             28887..29213
                     /gene="trxA"
                     /locus_tag="ACGI3L_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFG9196707.1"
                     /translation="MYIMVKIVNNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYE
                     ALGNEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKN
                     KIESYM"
     gene            complement(29420..30694)
                     /locus_tag="ACGI3L_000981"
     CDS             complement(29420..30694)
                     /locus_tag="ACGI3L_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9196708.1"
                     /translation="MQFMDVSKYIEGANLKVKTKSGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPLLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            31575..32411
                     /locus_tag="ACGI3L_000982"
     CDS             31575..32411
                     /locus_tag="ACGI3L_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9196709.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            32764..34341
                     /locus_tag="ACGI3L_000983"
     CDS             32764..34341
                     /locus_tag="ACGI3L_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9196710.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSNFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            34334..35518
                     /locus_tag="ACGI3L_000984"
     CDS             34334..35518
                     /locus_tag="ACGI3L_000984"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9196711.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIEKR
                     IL"
     gene            35536..36135
                     /locus_tag="ACGI3L_000985"
     CDS             35536..36135
                     /locus_tag="ACGI3L_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9196712.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            36159..36629
                     /locus_tag="ACGI3L_000986"
     CDS             36159..36629
                     /locus_tag="ACGI3L_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9196713.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            36988..37734
                     /locus_tag="ACGI3L_000987"
     CDS             36988..37734
                     /locus_tag="ACGI3L_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFG9196714.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            37795..38469
                     /locus_tag="ACGI3L_000988"
     CDS             37795..38469
                     /locus_tag="ACGI3L_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9196715.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKAEELADWISEYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            38837..40183
                     /locus_tag="ACGI3L_000989"
     CDS             38837..40183
                     /locus_tag="ACGI3L_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HFG9196716.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNIIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEKAYSIFYGDILESCNIVLMNRNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            40210..41610
                     /locus_tag="ACGI3L_000990"
     CDS             40210..41610
                     /locus_tag="ACGI3L_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28-related protein"
                     /protein_id="HFG9196717.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENRAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            41820..43256
                     /locus_tag="ACGI3L_000991"
     CDS             41820..43256
                     /locus_tag="ACGI3L_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HFG9196718.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            43600..44544
                     /locus_tag="ACGI3L_000992"
     CDS             43600..44544
                     /locus_tag="ACGI3L_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HFG9196719.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            44713..45645
                     /locus_tag="ACGI3L_000993"
     CDS             44713..45645
                     /locus_tag="ACGI3L_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFG9196720.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            45750..46217
                     /locus_tag="ACGI3L_000994"
     CDS             45750..46217
                     /locus_tag="ACGI3L_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HFG9196721.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(46461..47315)
                     /locus_tag="ACGI3L_000995"
     CDS             complement(46461..47315)
                     /locus_tag="ACGI3L_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFG9196722.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            47481..49445
                     /locus_tag="ACGI3L_000996"
     CDS             47481..49445
                     /locus_tag="ACGI3L_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9196723.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSYTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            49445..49906
                     /locus_tag="ACGI3L_000997"
     CDS             49445..49906
                     /locus_tag="ACGI3L_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9196724.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            49909..50229
                     /locus_tag="ACGI3L_000998"
     CDS             49909..50229
                     /locus_tag="ACGI3L_000998"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFG9196725.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            50245..51345
                     /locus_tag="ACGI3L_000999"
     CDS             50245..51345
                     /locus_tag="ACGI3L_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFG9196726.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            51465..54065
                     /locus_tag="ACGI3L_001000"
     CDS             51465..54065
                     /locus_tag="ACGI3L_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFG9196727.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLNKSNDAFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTIFTKGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNKMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            54534..54869
                     /locus_tag="ACGI3L_001001"
     CDS             54534..54869
                     /locus_tag="ACGI3L_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9196728.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            55006..56283
                     /locus_tag="ACGI3L_001002"
     CDS             55006..56283
                     /locus_tag="ACGI3L_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein/redoxin"
                     /protein_id="HFG9196729.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            56404..57792
                     /locus_tag="ACGI3L_001003"
     CDS             56404..57792
                     /locus_tag="ACGI3L_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9196730.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEEL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            58238..58876
                     /locus_tag="ACGI3L_001004"
     CDS             58238..58876
                     /locus_tag="ACGI3L_001004"
                     /inference="COORDINATES: protein motif:HMM:NF037435.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HFG9196731.1"
                     /translation="MKSKEEIEWLLNRDYKIDPVVTFVGDRYQFSIRQRDALKRAVCT
                     DEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISIEVALSGGTLVIGSDGNIRDLAGLRG
                     TYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDAPVSNSGNLKYRILEHAKTWGIETEV
                     ELVKNADVVLEKLDRVVSSDAVIVDKCISYFNVARGIIEEYIKECNIINLNK"
     gene            58994..59863
                     /locus_tag="ACGI3L_001005"
     CDS             58994..59863
                     /locus_tag="ACGI3L_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9196732.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(60018..61163)
                     /locus_tag="ACGI3L_001006"
     CDS             complement(60018..61163)
                     /locus_tag="ACGI3L_001006"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFG9196733.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(61496..62272)
                     /locus_tag="ACGI3L_001007"
     CDS             complement(61496..62272)
                     /locus_tag="ACGI3L_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFG9196734.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            62854..63828
                     /locus_tag="ACGI3L_001008"
     CDS             62854..63828
                     /locus_tag="ACGI3L_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HFG9196735.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            63926..64231
                     /locus_tag="ACGI3L_001009"
     CDS             63926..64231
                     /locus_tag="ACGI3L_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9196736.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            64387..65547
                     /locus_tag="ACGI3L_001010"
     CDS             64387..65547
                     /locus_tag="ACGI3L_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9196737.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNLD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            65597..66499
                     /locus_tag="ACGI3L_001011"
     CDS             65597..66499
                     /locus_tag="ACGI3L_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFG9196738.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            66579..67472
                     /locus_tag="ACGI3L_001012"
     CDS             66579..67472
                     /locus_tag="ACGI3L_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HFG9196739.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      67525..67706
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            67934..69064
                     /locus_tag="ACGI3L_001013"
     CDS             67934..69064
                     /locus_tag="ACGI3L_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9196740.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTQEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            69136..70161
                     /locus_tag="ACGI3L_001014"
     CDS             69136..70161
                     /locus_tag="ACGI3L_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFG9196741.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            70164..71360
                     /locus_tag="ACGI3L_001015"
     CDS             70164..71360
                     /locus_tag="ACGI3L_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196742.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(71488..72213)
                     /locus_tag="ACGI3L_001016"
     CDS             complement(71488..72213)
                     /locus_tag="ACGI3L_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFG9196743.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSVDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
BASE COUNT        28152 a         7636 c        12307 g        24206 t
ORIGIN      
        1 atttacaata taaaaaagaa taaagagata aaagaaaaca tgattgcttt ctatttagtc
       61 ttattagggc agatattcca aatttacaca ataactattg ttatcatgtt tacctatatt
      121 tataaatttg ttggaattaa acaaatcata agcagtatta aagaactaca atggggaaag
      181 agctataagg ctcttttttc ctcaattgca gtatgcttaa tatcgttatt tgtaatgata
      241 attagaataa agttaattat gtagaggagt gtctataatg ttctttaaaa gaaaaaaaga
      301 agcaattaca attaattcat acattgatgg aaaaataatt aatcttggag aaattcctga
      361 taaagtattt tcaactaagg taatgggaga tggatttgct atgatagcaa aggacaatat
      421 tcttaaatca ccgactaaag gagtaataag ttttattgct caaactaacc atgctatagg
      481 aattaaattg caaaatgatg ttcaaattct tattcatatt ggattggata gtgcaacaac
      541 aaaaaaagaa aactttaaat tagaagttaa acaaggtcaa gaagttaata tgggggaaaa
      601 gttagtagaa attgataata agttacttga aaatacttta tatattcctt tagttattgt
      661 agagaatcct aatacggtaa aatatcatct ttcaaactta aatcaggaag gaaatagtgg
      721 tattaaagtt atcaattttg attgattatg attaataaag cgattaaatt taaatttatc
      781 atattctatt ttttctcata tattattttt gcctttgctt caacaaaatt cacacctttc
      841 ttatcaaaat taggttactc agcgtttgaa agaggaatta tattatcgag ctatgcaata
      901 accaatatat tgtttcaatt attatttgga gtattagctg ataagtatca aacaatgaaa
      961 aaaattgttt taattagttt atcagtttat ggaattgcat cagttattat gttttctact
     1021 gaatctgcaa cttttataat atacttatta cttgttgctt tatcaggagg attattaaat
     1081 acttgctgta gtttatatga tacatggata ataggttgtg gagataatat taataattat
     1141 ttgtcattta ttaagacttt tgggtcgatt ggatgggcta ttggaagtat ggtagcatct
     1201 tacttgattc ttagattctc atattttgga ttatctgtag cgattggttt aattgtagta
     1261 ttacttatta taaatatact attattacct gatattgaaa agattaataa gaaaataaat
     1321 gtaactaata aagatattat tgaattatta aaagataaaa aatatatctt actagtatgt
     1381 attttattct tattatactc aatggtggta gcaaataact gtactgtaat agataaaatg
     1441 atagctttaa atgctacaaa ttctcagata tctttaaagt ggtctttaca gtcattgtta
     1501 gagataccaa catatctggc tggttcttat ttattaaaaa aatatagcag tttaaactta
     1561 ttaaaattaa gtgctattat gataacagtt cagtttctat tatttgcttt aacaaatgat
     1621 tcaaatatca ttattatact gtgtgttttt caagtgtttt ctactccttt aattttaatt
     1681 acttcaaaaa gattaatatt tgaagtttct cctaaaaaac ttagaagtag tagccaatta
     1741 atagctttaa gtatatttat gggaggttca tctctgatta ttccaactgt tgctggtttt
     1801 ttgagcatta atattgggta taattataca ttaatggtat taagtctttt tggatgctta
     1861 gcttattgct tgatagtctt attgaattat cttcaggaat aattgtttta atatatagta
     1921 gtaatatcac ttgtttatag tatctgtatt tgccacaatc aatgtgtatt ttggtttttt
     1981 atagagaaga ataattgtat agattagagg cttcttagga gcttcttttc tttgtttata
     2041 caaagaagta aatcatgctt ttattttaag atatttctac tataattata atagtcttcc
     2101 atatgttaca aaagtgtaat gctaacagtt aaaatgtaat atttacttaa ggatttattt
     2161 atataaaacc tttaaaataa atatatatta aaaaattagc aactggaggc tattattatg
     2221 aaagaaatat taaaaataaa aaatatatca aaagattatg gaataaaagg atttaaaaca
     2281 aatgtgttaa aaaatatatc tcttacagtc aatgaaggtg attttatatc aataatgggt
     2341 ccatctggtg caggaaagac aacattgcta aatttaatgt ctacacttga caaacaaact
     2401 tcaggagaaa taatactaga tggaattaat atatcaaaag taaaaaataa tgaactatca
     2461 aaattaagaa gagaaaaaat agggtttata tttcaagact ataatctatt agacaatatg
     2521 aaactaatgg acaatatagc acttcctcta gcattaggaa aaaagaaaag taaggagata
     2581 gaagctaagg tattttctat agctaaaaaa tttggattag aaaatcattt agataaatat
     2641 ccatatcagt tatcaggagg acaaaaacaa agaggcgcag cagctaggtc attaattaca
     2701 aatccaacag tcatatttgc tgatgagcca actggtgctt tagactctaa atcagcatat
     2761 gaacttttag aatcattaga aaaaataaac agagaaaata acgctactat tataatgatt
     2821 acacatgacc ctctaacagc aagttattca aatgaagtat atatgataaa tgatggaaat
     2881 ataaagtgta aattaaacaa aggaaatagt agaaaagaat tttatggaaa aattatggat
     2941 atgctagcct ctatgggagg tgagatgtaa gtgagtatac ttggaattgc ttataataat
     3001 tttaagagta acataagaac ttatctagca ttttttatat ctatggtttt ttcagtagtt
     3061 gtgctaacta attttgaatt attaagatat ggtgatgcta taaatgtgtt acaagatgaa
     3121 aataaaaaat ttacactatc agtgttagta gctgtaataa tgatactatc agtattttta
     3181 tttttcttta tatggtatgc aacaaatata ttttttaaga ataggtctaa agaaattgga
     3241 atattgtctt ttatgggatt agatttatat actataggaa aaatatattt tgtagaaaat
     3301 atgcttatag gaataagttc ttgtataaca ggaataatta tagggataat aacatctaga
     3361 ttttttcaag tagtgataat aaagttatct ggatttaata taaaggtatc taatggactt
     3421 agtatagaag ctatactata tgctacttta atctttattt ctatatttat aataatggct
     3481 gtaaaaggtt ttataacaat atgtagaagt agtgtaataa atctaatcaa tatatctaaa
     3541 aaacaagaaa aaataccaaa ggtaggaata ggtatatata tattagctat agtatcaatt
     3601 atagtaatag gatatggcta ctatctttct accaatataa gaactggaga tataactagt
     3661 gtactacctg ttataggtat aataatagta ggtacttatg gattattcaa atcagttatg
     3721 cctgttatat ttgatattat aatcaaaaat aaaaaaatat tatttaatgg aaataatata
     3781 attgcaataa acaatataaa ctaccgatta aataaaaact ataaaactta tgctataata
     3841 gctataatta taactacaac aatatcaact cttggtgctt cagttgcgat gaagcgtata
     3901 cataagaatg cccaagaaca aagaaatgtg tacactatta gcatagtttc aatggataaa
     3961 gatgaagtga ataaaaaaca aatagagaat ataataaaag atactaataa gataaagtac
     4021 tcagtaaatc cagaactaac aattttaaag aaaacagata taaaagaagc ttatgataca
     4081 acagatacta taatgaaata tagtgatttt tgtaatactc ttaaagtgaa tggcaatgat
     4141 aaagaattaa aagagtatgg tgaaagatta gttagtggaa ataatgtaat agagttaaaa
     4201 agccctcaaa cgatagcatc aatagctaca aaagaagcca agataaaact tgatggtcag
     4261 ttatataata tttcaagggg agaagtaaaa gttccagtac tagggacagg acttaatcaa
     4321 agtattatag tggtaaatga tgatacatat tttaaactaa gagataaggg tcaacaagtg
     4381 tatttttatg gtgcaaaggt atttcaagaa gaaaatagtc aagtaatgtt caacaatatt
     4441 gaaaagaatt taagtttaaa aaatgggtat attcaaaatg gatataaagc tcaaggtgag
     4501 agtcaatgga tgaagtttgc atatgtagtg cttgtgtttt tattcttagt ctttgcaatt
     4561 gtagctggaa gtataatata tatgaaaata tatagtgatg catatgaaga taaagagaaa
     4621 tataagattt tgttaaaaat aggtactaca gaaaaagata taaatagagc tatacttaaa
     4681 gaagtagcta tgttttatac tttgccaatg ttaagtgcaa ctatatctag ttattttgca
     4741 ttgagattag caggagattt attgatgacc gatttatttg gtatatatat actaagttta
     4801 gtgatatgtt tgataatatt cataatatat ggagcagtat ctgttaataa gtttaagagt
     4861 gtagtgtata aaaattagtt gatatattaa taaagagaaa ggagattctt gtaataagag
     4921 tctccttgtt gattaactaa ataatttggg taataaattc atataaaata tgttatgata
     4981 ttaataattc atagcatagt gaaatattag gataatggag aatatacaaa tgtatagaat
     5041 tttattagta gaggacgata ttgatttatc aaaagagatt gcattagcac ttgaaaaatg
     5101 gggatttaaa gtagaattaa ttgatgattt tgaggtagta ttagatgaat ttatagataa
     5161 aaaaccagat gtagtacttt tagatgtaaa tttaccatta tataatggat tttactggtg
     5221 cgaaaaaata agagctattt caaatgtacc attaatattt ttatcatcaa gagattctga
     5281 tatggattta ataatgggta taaataatgg agcagatgat tacattacca aaccattttc
     5341 tatagaaata ttggttacca aaataaatgg tataataaga agagtctata attatagtga
     5401 ttctaatagt attttgtatt gtgaagattt gatgtttgat gtggggaaag ggattataaa
     5461 acataagtat aaggataaaa gtatagagtt gactaaaaac gaaataaaaa ttttaacatt
     5521 attattaaaa aataagaata gggttgtatc aagggaaagt cttatgatga ctctatggga
     5581 taatgatgag tttgtgacag acaatgcact tactgtaaat atgaatagat tgagaagtaa
     5641 agttaaagaa ctaggttttg atgattttat aaaaactaag aagggggtag gatatataat
     5701 acaatgctag taaaatattt gaaaggtagg tctaagtata ttgctctacc tttagttgta
     5761 gttagtataa taaatatcta cttatttgct atagatattt ttaaaaataa atattcagag
     5821 ttaatatatt tagatttttt agtactgttt ataataatgg tattttttgt tatagattat
     5881 ataaatttta gaaatagtta cacaaattta tataattgta tagaaaatag tggtgaaata
     5941 gacagttatt tagttgatgg acaatctttt gaagaaaatc taataaaaga tattatagaa
     6001 aacttaaaaa taaaaaataa tagtgacata gagacttata aacaatcatt aaaagaattg
     6061 gatgagtaca tagctaaatg ggttcatgaa ataaaaattc caatatcttc tttaagtata
     6121 attacagata ggttaagtag catagaagat agtttggata ttaagaatca ggttgcaaag
     6181 ataaattttt tagtaaactc tattttgtat agtagtagaa gcaacactat gtttgaagat
     6241 gtatttataa ataaatttaa tttagaaaaa ttgataaaaa tgtctataaa aaataattca
     6301 tttttgctta taaaaaataa tgtagaagtt agtttgaatg aattagaaaa tgatgtttac
     6361 acagattcta aatgcatgtc atatgtttta gaccaaatta ttaataatgc tataaagtat
     6421 tcaaaggaag ttggtaagat tgaatttaat tcaaaaaagt tagaaaatgg agtggtatta
     6481 tctataaaag attttggtat aggtataaat gaggaagata tatctagggt ttttgacaag
     6541 ggatttacgg ggaaaaatgg aagaaatcaa ttgtataagt ctactggaat ggggatgtat
     6601 tttgtaaaga aaatgataga tagtttaggg catgagattg aggtatgttc ggaaaatggt
     6661 tcatatacaa tttttaatat ctatttttat gatatatcgg attatttaag cctagatagt
     6721 taggttatta gactataaaa tctatcatca tatacaaatc gacatataca ataagaataa
     6781 atttagttct tgaaaatagt gaagatttaa ttagtgcctt aaatgatgct ctatctatat
     6841 tataaaataa taattattat atatgaaaaa catatcagat aggtacctgg tatgtttttt
     6901 atttgtagta actattttaa tatggttttt ggagagagaa tatgttttgt ttgtgaaaaa
     6961 aaattacatg gtattacatt gacactgaaa ataaattaat gtaagattta gctaaggtaa
     7021 aaaacgtgta taagattaac tcaattaatt tcataagagt aaattatcgt aattaaagat
     7081 gaaataagat taattctaaa attattaaac ttaatacctt gatttgggga ggaataacta
     7141 taaacttaaa aggatgataa ctatgtatag tgtaggttta atgtcaggaa cttccttaga
     7201 tggagttgat gcagtactag ctgaaattag tgggaatggt agaaatacta aagttaagca
     7261 aatagaattt ataactctag aaattcctaa agatataaaa gacgaaataa gaaagtgctg
     7321 tatagaagag gaatcgagtg ttgatttaat ctgtagctta aattttaagc ttggatattt
     7381 atttagtaaa gctgtaaaat cagtgtgtca taaagcaaac tttcatatag caaatttgga
     7441 ttttatcgca tctcatggtc aaacaatctt tcatatacca agaagttata ataattttgt
     7501 atcttcaacg cttcaaatag gtgaaccagc agttatagca tatgaaacaa atacaaaggt
     7561 aatatctaat tttagagtaa tggatatagc agcaggtgga gaaggtgctc cattagtacc
     7621 atatagtgaa tttttattat atagtgataa caataaaaat ttagcacttc aaaatattgg
     7681 tggaatagga aatattacta taatacctaa atcatgtaac atagatgatg tatttgcatt
     7741 tgatacagga ccaggaaata tgataataga tggagtatgt caaagattat ttaatagaaa
     7801 gtatgataaa aatggatact ttgcatcaaa aggtaaaatt aatgaagaaa tgttaaaaga
     7861 tttgatgagt cataagtatc ttagtcaagc gccacctaaa agcactggaa gagaggtatt
     7921 tggacaagtt tatttggata acatgcttaa caaatataaa catgtagata aatatgattt
     7981 gatagcaaca gtaactatgt ttacggcaaa agctatatat tataattata aaaacttcat
     8041 acttccaaag gttaatgtag atactttatt aattggaggt ggaggagctc ataatctaac
     8101 tttaatagga tatataaaag agttattatt agaggttgaa gtattaactc aagatgaata
     8161 tgggtattct tctgatgcaa aggaggcttt ggcatttgta atcttgggca atgaaacatt
     8221 aaataattct ttttctaatg taatatctgc aacaggggct aaaaataaag ttattttagg
     8281 gaatataaca cctaaacctt ttggaggtaa atgacatgtc taataataaa aaaaagaaaa
     8341 gaaagaaaaa taataattat aaaaatgcaa aaagtacaaa aagtaataaa aatactaaga
     8401 aacaaatgga gaaaaatcaa agaacagatt ataatattcc aactataagt tttaaaagtg
     8461 gattaatatt aatagtttca tctctagtaa gtactgtagt ttttcctttg ttattatcta
     8521 tatttggaat agataataga tttggagttg ttataggaaa ttcattaatt acatcttttg
     8581 cagttgcata tacaagatac tttgttgaaa ctaagagagg tttttctttg ggatttttta
     8641 gactgtatat tttatttgct ttatcatttg caataatagg ttacttctgg atatataaag
     8701 gaatacatat ttaaaaaagt attgagacta ttttatgtta ataataagat agtctttttt
     8761 cttttttaag aaaagatatg agtattttaa gtagtgtgta attttagaca aaagaatgat
     8821 tagataaata aagcaattaa agcaagatat aaatgtatga aataaaatta caatttaaaa
     8881 tgtaaaatat gaaaaaaata tatacaaacg tattcctgta atcaaaaata catgctataa
     8941 tgattgaaaa gaaataaaaa aacaggggga atcaatatga gagtattatt tgtttgttca
     9001 tcagggatgt caagtgctat agcagttaat gcattacaaa aagaaggagc aaaaaatgga
     9061 atagatatag atgttttggc tgttggtact caagagtttg aggatgaagt taaaaatgga
     9121 tgggatattg ctatggtagc tccacaagtt agacatagat ttgactattt aaaagctttt
     9181 gctgatgagg ttagtgtacc atgtgcatta atacaagcac aagcttatag tccattagga
     9241 ggaccaaagt tattaaaaca agttcaagag ctgttgagta aatagtagtt gcagtgttgt
     9301 tagattagaa gaaagttaat tttataaaaa ttttaatgat aataaaaata aatattaatt
     9361 aaggagagaa aagatgctag ataaatttac agaattttta gacactaaat tatcaacttc
     9421 tatggccaga ttggcagaac aacgtcactt aagagctgta agagatggaa tcgtagcttc
     9481 attaccactt ataatagttg ggtcattttt cttgatatta gcatttcctc cattaccaga
     9541 ttcatggggg gtaactcagt atctaaagga aaatgcagtt acaatattac taccatatag
     9601 aatgacattt tttattatat cagtatattc tacatttggc ataggttata gtttggcaaa
     9661 gtcatataag ttagatggat tgacaggagg tttattagct acagctacat tccttttgac
     9721 aatagttcct actgcaatag agggtcttac ccctgattta ttaaagatag ttgaaaagag
     9781 tccagaactt ttagcttggt ataattcaat tcctcaagga tggcaaatgc caatggctaa
     9841 tcttggtgga ggttcaatgt ttgttgctat tgtaacatct ataataggtg ttgagattta
     9901 tagatttact gacaaatcta aattcaagat aaccatgcca gaagcagttc cagcatcagt
     9961 cacaaggtct tttgaagctc tgacaccagc cgcattaata ataattttaa tggctattgt
    10021 tacttatttc ctagggtttg attggcatgg cttcatagct aaattagtaa ctccattagt
    10081 ttcagccact gacacattac catcagtaat tatactaata tttttaataa cgtttttttg
    10141 gtcatttgga atacatggtg tatcaataat aggttcattg gcaagacctt tatggataca
    10201 attattagat gctaatacag cttcatatgc tgcgggtcaa gcagttccag gtattgctgc
    10261 tgaacccttt tttcaatggt ttatatggat tggaggttct ggagctacaa taggcttagc
    10321 tttacttctt gcatttagag caaaatcagc ttatggaaag tctttaggaa aagcaactgt
    10381 aataccagca atattcaata taaatgaacc aataatattt ggagcgccaa tagtattaaa
    10441 cccaatatta ataataccat ttgttgtagc accaatagta atggcaacag tttcatggtt
    10501 tgctatgagt gctaatttag tatccagagt agtagttact gctccttgga cattaccagg
    10561 accagtaggg gcatatttag ccactggtgg agattggaga gcttcagttc ttaacttatt
    10621 atgtatagct atatcaataa taatttacta tccatttgtc aagatgtacg ataagaggtt
    10681 gcttcatgaa gaaaaagttg aagagcaaga agcttattaa ttagaaacta tattggaaat
    10741 taaaaactat attagattag tataaatttc aaagtataac agttatgaaa taagtaacga
    10801 agatattttg ttgattgttt ataaaaaaag aaaaggtaaa cttttctttt tttataaata
    10861 tatatgaaac tttttttcat caaattttta aaaaagtttc gtgtaattcg aaataaattt
    10921 aaacacatat aggatataag gagatgacac agatgggaag attaggaata tcaatttatc
    10981 cagaaaaaac aacatctaag gaaatatatg attatataga taaagctgct gaaaatggat
    11041 ttacacgtat attttcatgt ttattatcag ttaaagatac taaagaaaat ataattaaaa
    11101 aatttaaaag tataaatgaa tacgctaagt ttaaaggttt tgaggtaata cttgatgtaa
    11161 atcccagagt atttggtgaa ttagaaataa gctacaaaga tttgaatttt tttaaaaaga
    11221 cgaaggcaga cggaataagg cttgatatgg gatttacagg ttctgaagag gcattaatga
    11281 cttttaatcc tcaaaatctt aaaatagaaa tcaatatgag taataatact aattatatag
    11341 atacaataat ggactaccaa ccaaataaag aaaatttgat aggatgtcat aacttttatc
    11401 cacatagata tagtggatta aatttagaac actttataaa atgtacagaa agatttaata
    11461 agtatggatt aagaacagca gtttttgtaa caagtcaaaa tgaaactaca tttggaccat
    11521 ggcctgtaac tgatgggctt ccaacaattg agatgcacag aaatctacct atagatattc
    11581 aagtaaagca tataatagct atgaataata taaatgatat aataatatca aattgttatc
    11641 caacatatga ggagctaaag gtattaggtt ctatgagaaa agatatggtt acatttgatg
    11701 tagcaataga ggaaaatata cgagaagttg agaagaagat actctttgaa gaaatacatt
    11761 ttaatagagg ggacatatct gatagtctga taaggtctac tcaatctcgt gttaaatata
    11821 aaggatataa atttgaacta tttaatactc ctaaaataat aaaaagagga gatatagtaa
    11881 ttgaaagtag tgaatatggt cattatgcag gggagttaca aatagccttg actgatatga
    11941 aaaacagtgg taaatcgaat gtagtaggat atataagaaa agaagaatta tttatattag
    12001 attatattaa accatggcaa aagtttaatt ttaaaccctc aacaaaataa tttattatga
    12061 aaatattaat ttattataaa aatataatta tgaaagttgg aattaaaatg tgtttaaaaa
    12121 tttaatatta agaaaatgag gaaatgatat gttaataaaa actttagaaa atttagttac
    12181 agaaggtaga aataagaata cattgcaaat agataaagaa gatacattag gcataataga
    12241 attaataaat aacgaagata aaactgtagc ctatgctgtt gaagaacaaa aggagagtat
    12301 agcaaaagct gttaatataa tagtagatag aatgaaacag ggaggtagat tattctatat
    12361 aggagcaggt accagtggga ggataggaat actagatgcc acagaatgtc ctccaactta
    12421 cggagtggat tttgagcttg ttcaagctat aatagctggt ggaaatcaag caatatttaa
    12481 agcaatagaa ggtgctgaag atgataaaga acttggaaag caagatataa tagatagagg
    12541 agttacatct aaggatgtta tatgtggtat agctgcatca ggaaggactc cttatgttat
    12601 aggtgcaatg gagtatgcta aggaattggg gtgtgcagta ctatcaataa ctatgaatcc
    12661 gaatagtgaa atgagtaaaa aagcggattt accaataaac attatagtag gggcagaagt
    12721 aataatgggt tcaactagaa tgaaaagtgg tacagctcaa aaaatggtat gtaatatgtt
    12781 aacaacagct tctatggtta agatgggaaa agtatactca aacttgatgg tagatgttaa
    12841 gacatcaaat gaaaagttgg ttgaaagagc aaaaagaata ataatgatag ctacaaatgt
    12901 aaaatatgat gttgcagaaa aattcttaga agaagcagat aatagcgtta aattggctat
    12961 atttatgata aaaagtggtt tagataagga tagtgcaaag agtatcctag atagacaaga
    13021 aggttatata agtgaagctt taaaatcaat agaaaaattg taaaataaat aatagtactg
    13081 ataacctttc aatattaaaa aaacagcatt ggaaggttat ttttagatat taagtattga
    13141 aagaattatt aaagatattg taggaggata gtatgtattt tttaggtgta gatggtggag
    13201 gaacgaaaac aacatttaca ttagtagatg aagaattaaa tatagtagga accataacca
    13261 aaggaacttg tcattataat caaataggat ttgataatct aacgaaatta ttaataactg
    13321 ggttggaaga agtttgtaaa gatgctaaga taaatgtaga agaaataacg tatgcatttg
    13381 ttggacttgc tggatatgga aaaataaaag aagtattgta tgcattagaa gtagcaacaa
    13441 aaaatgcata tagtcatata aattatactc taggtaatga tgtagaaata gcattagcag
    13501 gttctttaaa tggggaaaaa ggtataaata taattgcagg tactggttca atagcacagg
    13561 ctttagataa agatgggaat cttcacagat gtggaggatg gggctatgta ttaggagatg
    13621 aaggttcagc gtattatata ggaatggcta ccttaaaaat gttcacaatg cagtctgatg
    13681 gaaggtgttc aaaaacaaaa ttatatgatt taataaaaag acatcttaat atagagaatg
    13741 attatgacat aataaaatat gtaaatgatg aaataaaagg agatagaata gaaatagcaa
    13801 agtttgctac gatatgttta aaagcagtta ttgaaggtga taatactgct agtaaaatat
    13861 ttgatgatgc agcttatgaa ttaagtaggc ttataatagg attagagcat cattttgaac
    13921 aaggtacaaa gataaaggta tcttattcag gtggagtgtt taagtcagga gatttaatat
    13981 tagagccact taaaaaatat ttgaataaaa cgagatttgg tatagtgaga ccagtgttga
    14041 ctccagattt aggagcatgt ttacttgcta agaagaaata ttatagtaaa taggtagagg
    14101 tgatagagta tgagttgcat tttaaaatta aaacagatat atgaagattt aacggaagta
    14161 gataaaaaaa tagctgatta catacttaat aatacagagg ctataagtaa gctttctgta
    14221 tcagaattgg cgtcaaactc aaaaacaagt acagcaagta tagttaggtt ttctagaaaa
    14281 atgggatatt cgggttttgg ggatttaaaa attgagatag ctaaagattt gatgggcaaa
    14341 gaaaatgaat acacatatgt agatgaaaac tatgattgta atatagatag tgttataaac
    14401 aaaattacaa acaaaaacat agagactatc aaccaaacaa ggttgttgaa tgaaaaagat
    14461 ataataaaag aagcagttga acagataata aaggctaaaa atgtatatat atttggagta
    14521 ggtggttcgg ctttagttgc actagattta cagatgaaac ttttaaggat aaataaacag
    14581 gcatttacct ctttagatag tcatacacaa cttatgatat cttcaaatgt agataaagaa
    14641 gatatagcta tagcaatatc ttactctgga gaatcaaaag aagtaataaa gtctatagaa
    14701 aatgcaaaat taaaaggatg taaggtcatt tgtataacta aatatagtga caatcatctt
    14761 agtaagatta gtgatttaaa actagtagta ccaaatatag aaaaaaggct tagagaagga
    14821 gctatttctt caagaatagc aatgcttacg ttgatagata taatatatat ttctataatt
    14881 caagaaaact taaatgaggc agaacagaaa ctacaagaaa caaaaaggat acttgattat
    14941 ttaaatatta ataatgctta aaactaggtt atatatcaac taaacaaata agttagacta
    15001 taagcgtaag tcaataagaa atagataaat atctaaaata ttgacttact taataataat
    15061 atatagcatt tttataatac aaatgagttg tcttaaaatt gatttttttt aatcaaattt
    15121 taagttcaac tcctttttta tatttttata gatatatcct atattttccc agaaaacgta
    15181 ttgaatatac aaattataag aagtataatg ttgttgggag agaatgtatg aaatgtatac
    15241 aaagttgatt ttaactgtat tattgataat tctctttact cttaccatta ttaatgattg
    15301 aagacaatgg tatttattat aggtcaaaga ttccgaatgt attaatcatc atcattttct
    15361 caaactaaca gcaaacaccc tgatttgcga gttgtattgt atacaaatta tctagaaaat
    15421 atctattaga ttttccatga aatttaaata tttcacgaat gtatgaatgg agaaatatac
    15481 atgttgacaa tccacctttt taaatcctaa attaatttta ttaatggtag agaataggaa
    15541 gtaacaatgt tttataaagg agaatattaa gtatgaagaa aattaggaag ttagctacca
    15601 agttattgat tacaacaata gttttaatct caggtatgag tatgacagtt tatggtatga
    15661 cagccaaaga ggtaacagca aaaacaccaa aaagctatgt cactggaacc aatagcgtat
    15721 atggtccaaa gctgtcacaa gcccaactaa actcagtagc acaagcaaca gcagatttta
    15781 tgaacaagaa aatcacaaag aatatgacca cagatgctaa gattttagtt gcctacaatc
    15841 acattaaaaa taacacaaca tatgttgact ggaatgcagt agagggagca aatactgcct
    15901 atacattggt tactaaaaaa ggtgcatgct caggaatggc taggagcatg aaagctttgt
    15961 gtgatgctat gggaattgaa tcttattatg tacacagcac atcaaatgac caccagtgga
    16021 atcttatccg ttttggtgat gggcgtttgt atcatgtaga tattgatgct aataaatcag
    16081 caggaaagga tatcatatac aagagtctta gccacccatt accatttgat aagacagcat
    16141 atccaaaagt tggtgcaata gtacagacgg taaaaccaga acagacacag aaaccagcac
    16201 cacctgggaa gcacactatg ttaccacatc aagaaggggc aaaggctgtt ggaaattttg
    16261 ggaaaaaagg agaagatata aatgaaaaac atgtaatgta tgaaggtgtt cgatgtagtg
    16321 tagttaattc atcagtaaat acaattacat ttacaggtag tgaatcaaat ttagacccat
    16381 caaatcttac gattgctgta ataggattta tgaacacacc atatgggatg tttgcattag
    16441 caccagaggg taaacctgtt gaatatcctt ttaaatatga taagccattt tctttagatt
    16501 ttagtggtaa aaatcgttct ggtgcagaat tagcgaagta ctgtaaaaaa aatgatgtga
    16561 ctattaaaat agaaatcact gatgaaaaag ctaatattgg acttggtcaa ataatgtatg
    16621 ttcgatatga ataatgattt aatcatgaca gtagaataag ttataaacat tgcgccctct
    16681 tactaggggc gcatttaata ttatatctga tattttgtag tcaggtcaac tgctagattt
    16741 ctcccctttt tatttataaa aattattatc tctaagcatc tgagcatgtt tacgattaac
    16801 taaaaactgt tttaactcag tcaagcatag gaataaaata gctctatttt caaactctgt
    16861 tctgtcaaca ggtagaggct ggtttttcat actaagcatt agtctcttta attcttcaag
    16921 aagaagattg cctgtttcag cttcaaattc agtataacct atcttatgta taaaagcaga
    16981 tagaatatga gcttgtggtg gtgtagaatt tagttgagat acataactat acaaattttc
    17041 taagatatcc cgttgacttt ttataatatc catatgctct aagaagaatc tagtatcact
    17101 taataaagta ttattaatat tatcgtaagt ttcagaaata ctgctgtcaa taagtgaatt
    17161 taatgtatat aaatctctac tatatccatt ttctttttta ggatttacaa taatatctgc
    17221 aatgtctata agtacaatac tcacttcttc ctgtaacttt ttttgaactt catggatttt
    17281 atgtatattt gttggaatat acatatttat taagacacct attccagttc ctactgcaaa
    17341 tattccagct tcatttaaaa tccatttgat agaagtttct ccttgaaggt agtaatggga
    17401 tgctatgact acacacatag caataacatc ttgaatattt aacaaaaaac aaagtggtat
    17461 aattataaat ataaatattg aaaatgaagt caaattatat cctaaaatat taaaacataa
    17521 atatgaaaaa atagtacata aaagaaaacc ataaatcttt ccaatggagc ctttaagagt
    17581 ttctctttta gtgtccttta ctgtaagtag tactataact ccagcaacca ttgaatattc
    17641 taattttaat agccaagcaa taaatatagc aagagaacat ccaagagata attttattac
    17701 tttaagtgaa ttaatattat tcaaatgcaa acctcctgta aatcaatata ataaaattct
    17761 aacataaaac taatattgct tgaaaggtaa gtaactatac ttaattattt tattgcccta
    17821 tttgtttaga tacaatcaat ataattttat tttatgaaaa ttttttgtaa aattttaaat
    17881 ttagagacta acatgagacc acaaagagga agtttattat aagaagaaaa cttaaaattg
    17941 attttaaata gcaaatgaaa ataatcaaat atgtatatac tattattaaa aaataaaatt
    18001 atatagttaa tataatttta taattggttt agtatagaga tttttaactt ttatgttata
    18061 ctatttataa aagtaggtat aaagattaaa atacataatc aaatatgtat aagaggtttt
    18121 aaatagtatt gttaatgaac ttgattattg tttataatta caaattggag gagataaaca
    18181 tgaaaattac tgaaggatat atgcctttta aaggttttaa aacgtattac cgtatagtag
    18241 gagaaaatac ggaagggaag aagccattag tattacttca tggaggtcca ggttctacac
    18301 acaactattt tgaggtattg gataagatag ctgaaagtgg tagacaagta ataatgtatg
    18361 accaaattgg ttgtggaaat tcatttgtag gagggcatcc tgagctattt aatgcagata
    18421 cttggataga ggagcttatt gaactaagaa aacatctagg acttgatgaa attcatctgt
    18481 taggtcaatc ttggggaggt atgcaggcta tttggtatgc tattgaatat aaaccaaaag
    18541 gtattaagtc ttacatcctt tcatctactc tttcttctgc aaaactttgg gagaaagaac
    18601 aaaaaagaag aatatcatat atgagtgagg ttgaccaaaa agcattactt gatgcagtaa
    18661 atactggaga ttactctagc aaagaatata atgatgcatt agaaagattt atggaaatgt
    18721 attgtgcagg tgaagtgaca gaagattctc cagagtgcct gagaagacct aaaaaatcag
    18781 gttctgaagc atatattgta ggatggggac aaaatgaatt ttctcctaca ggaactcttt
    18841 ctggatatga atttacagat agattacatg aaataaaaga gccttgtcta gtaactagtg
    18901 gagcaataga tttatgttca ccatatattg caaagactat gtatgataga atacctaata
    18961 gtaagtggga attatttgag tattcaagac atatgccatt cgttgaagaa aatgagaaat
    19021 atataaaagt cttaactgag tggttgaatg cgaacgatta aaaactatat aaatttatat
    19081 aaaaaaatga gtgtctcaaa atgaactttt tagttcatta ggcactcttt ttgcatgaaa
    19141 tcaaatatat tttcattatt tgaacgataa aatgaggctt atatctattt tgggaaagta
    19201 attttttatt actagcgtta gattctaatc taattgtata cttattgaaa taatagaaat
    19261 atattggtgt ttataactta attttattgt tttttagaaa tttttttata tattggtata
    19321 attattctgt ttaaatttga ttaaaaagta tattaattat aataagaaac aattatataa
    19381 ataggaatag attattataa ttaatataga tataaaaata attatagaag gaaaggcaca
    19441 ttatggaaaa attgagagtt attgaaatga taaaaaataa tcccaatatt atagctacaa
    19501 tagataatcc aactgatgaa atgaaattgt tagctattaa agaaaatggg cttgtactag
    19561 aatatataaa taatccaacc agagagatgc aagaactagc aatagataat aatattagag
    19621 caattaaatt tatagataat ccaacagaag atatgatgat aaaagcagta aatgagggat
    19681 ggagtatact ggattatatc aaaaacccaa ctgataaagt tattgaaatg gctataaatc
    19741 aagcaggatg ggcaattaaa tatgctaaaa atccaagtga agaattacaa ctgttagcag
    19801 taagaaaaaa ttatgattcg ataaagttta taaaacaacc ttatgaaagt gtacaagagg
    19861 aggcagtgag aataagttat gatgccttga gatatataga ttcacctagt tataatgcag
    19921 aacttatagc tataaaaaat aatgaagcag ctattagctt tataactgat ttagataaaa
    19981 ataaaatgtt ggaattttta aaagtgaata ttttagtgat taagtacatt ctgaaaaaag
    20041 tatctaaaga tgaattagag agtgcattaa aagaagtatt atccaaagaa gatgttgagg
    20101 aaaagtatat tagagatttt ttgaattgta gtgttataga tagaaatagc gaaagtatac
    20161 caatagataa aattatgttt atttataaat atggaagtaa gacagcaaaa aaaatagctg
    20221 tagatgagaa attaaagatt atgtaggaga gagaaaaatg aattttatag acacattaaa
    20281 aagcgttgac ttaatattat ccactggaga agtaccttta atagtaggtg aaagtggaat
    20341 aggaaaaaca gctttagcaa ataagcttgc caaagaaaat gattggagtt taattgttat
    20401 tgatggaaac ttacttaaag agggtgaaat aggtggtctt ccaactatag aatcttatgt
    20461 aggagttaat tctaatggat ataagactga aaagaaaaca acagtgtatg ctgttcataa
    20521 caaattaaga gaaattgatg aagagatatc taaaagtaag acagttcttt tatttataga
    20581 tgagataaat cgttgtgagc atacagtaca gcaagaactt atgaatttaa ttttaaatag
    20641 agaaattaat ggatataaac tgcatgatga tgtaaagatt ttagcagcaa tgaatccatc
    20701 aagtaaatat ggttcagatt ttgattatca agtggtagat atggatgcag cccaagaaaa
    20761 taggtttgtt tggttaaata tggagagtga ccatacacaa tggataaaat gggcaataga
    20821 tgagggtatt gaaagaaaag ttatcgagtt tatttccact tttccagaat atctgcataa
    20881 aataaatgaa gatgatgtaa gagccactcc tagaagttat gagagagtat ctaaaattta
    20941 taaagtttat aaagaaaaaa ataattctat tcctagagca gtatttttaa atgttgtaaa
    21001 gggtaatgta ggtaaagtta ttgcagaaga atttataagt tttattgaat caaactctga
    21061 accattaata tcctatgaag atgttttttt aggagaatct attgatgagt ctattgtaga
    21121 aagagtaaaa aatgagagtc atacaagact ttatctatca gctatgaaca ttctaaaaga
    21181 cttagaatta aatattaaga atgataaata tgaatcaaac cactatatta atagatttat
    21241 tgaattttta aaaatgtatc ctgtagattt aatgataggt attatgaagg atattagaaa
    21301 cagttatatt gaagtatata aaaaagctat agaaaatgaa gagtttgtaa aatcatattt
    21361 tgaatcttat agtttaataa ggggataatg tatggaaaat tattttgata aacaagcaaa
    21421 agagctttat aataaagcaa gtgaaattat aaatactcat tctatgctaa aggcaaatcg
    21481 tgctaatgag aaatttgata tagatatacc acaagatttt aagtatgagt tttttagtct
    21541 tgtagataaa gtgaatttaa gtcttatgga agaagaagat aatttttatg gatatttttt
    21601 gtttcagatg tcaagagaaa taagatttga tataagtagt cctacaggtg tgaattttaa
    21661 gggagctaaa tatattatat attttaatcc aataatcttt ttaacgcttg acataaagca
    21721 aatggagact acaattaaac atgaaattca tcatatatta tctatgcatt tgatgagagc
    21781 aaaggagtta aaaggaaagt atagtacatt agcaattaat atggcaatgg atatagtagt
    21841 aaataaattt ctaaacaatt taccaccata tgcaactacc ttagagtggg taaatttaaa
    21901 atattcctta aaacttgaac catatgaacc ttttgaatat tatgtagaaa agattcagac
    21961 tgaattagat ttgatggaag tggatgaaga tggtgaggaa gatgatagtg ataaatatgg
    22021 agatatagaa attgattata gccccgaaag aactcatgat atatgggatg aatccaatga
    22081 gatagatgaa aataccctta gagaatttac tgaaaaattt attaacagtt ctcaaaaagg
    22141 taaagttcct gcttatttag aaagtatgat atcatcactt aaaaatagta agggtgaatt
    22201 gccatggaat ttatatctta atagaataat gggaacagtt gaaaataata aaaagaagac
    22261 tataacaaga agaaatagaa gacaaccaaa tcgtttagat ttgaggggag aacttagaag
    22321 tcataagtca gaaatagcag ttgcacttga tgtaagtgga agtattagtg atgaagagtt
    22381 taaacaagct attaaagaag ttcttagtat agtgaaaaac tataatcatg aaattacaat
    22441 tatagaatgt gataatgaaa ttagacgtgt atataaagtg agaactgaaa aagatataaa
    22501 agatagaatt aggataggtg gaggtactag attttctcca gtctttgagt atgctaataa
    22561 taaaaagatt aatttgttag tctactttac tgatggtaaa ggtgaaaata aactacaagt
    22621 aatacctaga gggtacaaaa ttttatgggt tatttctgga agaggagata aaatttcatt
    22681 aaaagaacct tatggagcag ttaaaaaact tactaaggtt aaaacaaatg atgaaatatt
    22741 agaaataaat gatgtaagaa atgatgggta ctcaatgaat agccaagcac caattttata
    22801 ggtattcaca ggagataagc tgtattaatt tattttgata tgcttgttat aaaaatctaa
    22861 aaaatacatt aatcaatggt taatgtattt tttaatttta ataatataag ttttacttac
    22921 atttaagtct caaaatgtgt taaaatataa tatatagcag atagttttgg caaggtggat
    22981 ttagttgtca aaactatttt ttttattaag gatggtgatg tttttgttta agattgatga
    23041 ttatataatg tatggtatga caggagtctg caaagtcatg gatataacaa atgaacgatt
    23101 tacaaatgga ataaaaaaag agtattatgt attgagtcct atttattcta ataatacagt
    23161 aataaaaatt cctgtagata atgaaaaagt accaatgaga aagttacttt ctaaaattaa
    23221 tgtgctttca ttaataaatg atattcctaa tatggataca tcatggatag ataatgaaaa
    23281 attgagaagt gagcaattta aaaaaatact cagaggtggt aaatgtgaag agttaataaa
    23341 attagtaaga agtatagata ataacagaga gtatgtaaaa tctattggta aaaaaacaca
    23401 tcaagcagat gataatataa tgaaagaagc tgaaaggtta ttaaatgaag aatttgcaac
    23461 tattttagat atttctccta atgaagttag ttcatatatt tcaagtcata tacctcaata
    23521 aagtgtttta gtatccttta tttaatctat tttaagtatt atttatgtat gctggttttg
    23581 gtaaaataaa atatataatt aaattatata aaaaataata atgattgtat tgaagaatta
    23641 cagaatagtg cggagagcct actcctttag gtgtgagatg gatatcactt aaagatttaa
    23701 attgttattg tagatgtttt taatataaaa caagattaat aagtgtattg taagctttaa
    23761 gtgaaattga tactataatg agttacttag attttaaaat atataatatt ataaaaaatc
    23821 cttttaggtt ttgaatgaat aagatggata ctatgttgaa tagaatccat cttatttaag
    23881 ttttatttat gttgtttatt tgtaagcatt atttttgtac atgaaaacac agtgtaaaaa
    23941 tatgcttaga attatgaagt tttattaaaa agatattcga caaaataaga ctaaaaatat
    24001 tcttaaactt ataactaaga taaatattgt atatttatag tgtagcctga aaaattgtgg
    24061 atgtacgaaa tttatttagt attttattga aacaaagtag aagaagtact atagtttatc
    24121 tttgaataga ttgttatttt ttagtgaaaa agttattagg ttaatacata aatataatag
    24181 cttataaata gtttaagcat gttaaaaaag tagttattag agatatatag ttacattgct
    24241 tataagatac ttaaaatgat agcattcact tatattcaga agattaagat aaaaaatcat
    24301 ttttatatag taaagcatac ctaaatttag aaaataattg aatttataaa attaattaaa
    24361 tacataaaaa agtattcaat caacttaaca aattttctta aatttaattt aaatttttta
    24421 ttctattaat tattaatatt attttcaaat caatgcagtt ataagaagtg tataatttga
    24481 ttattatata ctgcatacaa aaatatattt gagcaaataa gtaaagtaat aaaaaaatca
    24541 agatttcata tctaaaaact attctgaaca ttaatttaat ttatattttc ataggaaata
    24601 ttttatataa tataattgat aaatataatt tgaatttttc taattattta ctgtcgatta
    24661 atagattttt ttcttgcata taagtgcata tttatggtac gatttacatg gtgaaataaa
    24721 aaaggggagg tgaaaaataa atattcgtga aaaagttttc agtttgaggt attttatgaa
    24781 taatatattt tgaggtattt tataaataat atattataca taaagagtat agcctcaata
    24841 aatagtatca aagcgaatat atgggtaatt actttaaaat aacagttttt atgtttagat
    24901 tcacagtgtt tattataaac taatgtgtaa gaaataagcc taatctgtga atagatagta
    24961 gtttagttat ttaagttgag aattggttgg gtgaagtaat atataaattt aaaaaataaa
    25021 taaaaacatt atttgaacaa aatatatgtt gctttattcg agactccttt aaaaaagcac
    25081 taaaatgtaa ttacataagt tgctacaaaa gggggatttt agtttgtaaa atactatcac
    25141 gtaaaaaata agaattgcat atggcgaagg ttttttcatg gtattagatg agaatatatt
    25201 aatttataac tatatctgaa aatagtgaat ttatataatt taaatttatg attaagaagt
    25261 gtattaattt tattccatga gaatatgtac tctacaaata aatgcgcaat tatcttaata
    25321 ataattacaa attgttttac aaaataataa tattatatct ttcataaaag aaagaatttg
    25381 gacaaaacgt aaaaaataaa aatacaatta agaaaggatt taaaattatg agctcaacag
    25441 taaaaaagaa gggtaaattt cctatgggat tttatatctg ctcaacaact ttctcatttg
    25501 aaagagcagc atattatgct tcaaagtact taatatatat attccttaca acagctatag
    25561 ttcatggtgg tcttggaata gataaaggac aagctgctat aatgcaagcc aaccttgttg
    25621 cattcacata ccttgcacct ataattgggg ggtatatatc agatagatgg ataggagcta
    25681 gatatactat acctataggt atgcttatca tgggggtagg atactatctt ggttctattg
    25741 caactacagt ttctatggta aatgcaatga taatcttagt ttcaattggt actgcattct
    25801 ttaaaggtaa cgtatctgcg gtaaatggac agctttttga tagtcaagaa gaacttgata
    25861 cagcattttc agtacaatat tcttttgtta atataggttc ttttattggt actatagcag
    25921 ttggtattct ttaccttaaa acatttgcaa aaaatggtgt acttggattt tctcaatgtt
    25981 tctttatagc agctgtactt tgtgtaatag gtgcaatatg gttcatatat ggatggagat
    26041 tccttgggaa tgcaggaaag agacctttta aagaaggtgt agttgctgaa aaaattgaag
    26101 aaaaagataa gtctcctctt acaagcatgg ataagaagag aatttgggct attatactta
    26161 tatcattctt ctctgtaatt ttctgggtat tctggtatct aacttatctt gcagtttatg
    26221 attatggtgc agcatttgta aacatgaatg ttggaggatt tgatgttcct cttgcttggt
    26281 ttgactcatt aaattcactt gtatgtatag tattaggacc agttcttgga gcattatggt
    26341 ttaaacttgc tagtagacca caaggagata tgagtttatt taaaaagaca ggtcttggat
    26401 taatattctt aggtcttgca ttcttaatgc ttgttggtgc agaattttca agaggagttg
    26461 gagctcctga aactgctaaa gctagtatac tatggataat catgtttggt attcttttaa
    26521 gtcttggtga aatgttattc tcaccacttg gtaactcttt tgtaagtaag tatgcaccta
    26581 agaagcttct aggtgttctt atgggagtat ggacatttgc tacttttata gctggtaaag
    26641 gatatggata tatatatgca tttactctta aatttgatat gattaaagta tatactataa
    26701 ttccagtaat actatttgtt gcagcgatat tattattctt atctgataag acattaagta
    26761 gacttgttga ggacgataaa taatcagtaa gcaattatta tgttttatag gttaatctac
    26821 tgtaattatg ttgtattaga ttgatttata actaattaat aataaaaata aaattttact
    26881 tctaaataca atattatgat atatataatt ataatatttg ttagagtatg attattaaat
    26941 aaaaataaca aataaaaata ctagctttag ttagctagta tttttatttg tttttattag
    27001 gtatgggatt aatacataat ttcaccactt aagacagtat aagcacttcc tccaattttt
    27061 acagaagtta tgttattgtt ttctctagtt atatttacat atacctttcc aggtctgttt
    27121 ataaagttac cttgctcacc aataaaacta gttttatcta aaatattgtg atgtactata
    27181 taagatgata cgcaagcgtt cccagttcca catacagggt cttctgtaac tccaacatat
    27241 ggtgctatag atcttaaatg gtagtcacac tttttatcta tagtttctat acaaaatgga
    27301 gttataccaa ttatattatt atcaccacta aattttttga ttttatttaa atctggagag
    27361 atatttttta aatcatctaa agattttaga ccaaatacaa gccaccaaag tccagtattt
    27421 acctttataa taggatattc aagaagtcta tcttcatgca cacctatcat ttgtgcaagt
    27481 tcttttctgc aattatctaa attttcaaat tcaggtgtat tctgttccat cataaatata
    27541 ttttcattat ttattttctt aagctctaca gataatacac cagcttttgt ttcttgataa
    27601 aatatacttt tattagtatt aagcttccct tcttccaaaa gtgcatggaa agtacctatt
    27661 gttgcatgac cacataaatc aacttctaaa cctggtgtga aaaattgtac tttaaaatct
    27721 gcaatatttg actctgaaac aaatgcagtt tctgataaat tcatttcttt agccacattc
    27781 tgcttaattt catcagaaat gttagaggta tcagtaacga caccagcagg atttccacca
    27841 aaaggtatag ttgtaaaagc atcaacttgt ttaatcttaa ttttgttcat ttttataacc
    27901 tccttttatt tgttctgaaa tataaatttc atgttttatg tattgaactc caatatataa
    27961 aatgttagag ttttttgtcc aaattgaaat ggcctcactg ccttctgata agtttcctgt
    28021 caatatttca tcattatcta caatcaaaat aattcctttg taaagcattt tattttcaag
    28081 tgtagtttta ttacctccat gaatatgaat attatcaaga cctttcagac ttttgttttc
    28141 taaaagtagt atttcaatat taatattttt tttgtaagca attaggagtt ctttttttaa
    28201 ttcaagaatt tcttcataag ggcaagaaat tataatttct tgttttgcat tttttatcat
    28261 ttctattgct ttttttaata tatttttatc tccttttatg tttaatacgt attctacact
    28321 tttactttta tttaatatct gtaagctatt ctttagatta tccatagaat tgtcaaattc
    28381 ttttttctta ttttttaata attcattagg gtttattggt atgtacttaa tagggtcagt
    28441 tccaacattg ataattatat tattgtttaa tagctttgtt atattttcat agacttttga
    28501 ttgtggtaca cctgataatt tacttatttc atatcctgtt aaagggcttt cctttaataa
    28561 tgatatgtat atttgagatt cgtatttagt aaatcctata ttttgtaatt cattaataat
    28621 attatccata tagaaactcc tttgataaaa gattagtaac tacctatgta gttattaatt
    28681 tgattttata atttaaggga aaaaatgtca actatattaa gaaaaaaata aaatatatta
    28741 gaaatattta gtcttataaa tatttaatct tataaatcta tttatcataa tattaaatct
    28801 attaaaaata ggcggttaca aaaaagtgcc taattgaact gttatatagg tcgtagtata
    28861 ttaatatcaa gaagataata aaggagatgt atattatggt aaaaatagta aataataatg
    28921 aatttataaa tgaagtagaa aataaagatg gtttagtagt tgtagatttc tttgcgactt
    28981 ggtgtggacc ttgtaagatg ctatcaccaa tatatgaagc tttaggaaat gagatggttg
    29041 aaaaagcaaa cttcttgaag gtggacatag accaaagtat agaattagct cagaaatttg
    29101 aagtatctac agtaccaact atgctaatat ttaaggatgg aaaacctgta gatagattaa
    29161 taggttttat gcctaaggag aatttaaaaa acaaaattga atcatatatg taattaaagt
    29221 aaattgaagt aattaaaata aatctcatat ataaacaaaa aaactcattg taatgagttt
    29281 tttgtttgta tagtgtaaaa tagtttgtat agttacaaat gagtgtctaa ttgctaatga
    29341 aattgactgt tgatataatt tgcttttttg tgaaaacaaa actactctct atttattgat
    29401 aaaaaagaat agaaaaaact tatttaaaag ccaaagtttt aatagcatgt ataaagctat
    29461 ccacctcatc aaaagtattg tacattccta agcttatcct aacaagacct acaggatttt
    29521 ccctcataaa tctgacatat gcttcttttg gacttatacc taataatttt tgtacataaa
    29581 tatctgcacc tactactcca gctccagttt ctattccaaa gttatcaact aaatattttg
    29641 ctacatcttt gtaatacata ttacttatat taaaagatat atttgggata attacattat
    29701 ttgatttatc tccatatatt attatattag gtattttact catttcttct ttagcatata
    29761 aaaataattc tctttcgtat tttgaaattc tgtttagacc aattttattt aaagtgttca
    29821 gtgcttttcc cattgcaaga gttccaaaat actctgggta tcctgcttca aaacgttggg
    29881 gtacgtttgc atatagtatt ttgttatcat ttacaaattt ggtagaacct gagccatata
    29941 gtacaggatt aaatttttca aagaattttt taggtcctac cagagctcct ccatttagtg
    30001 gagaataaca tttatgagca ctaaaaacaa caaaatctat atgctcatca cattcatgtg
    30061 gcatcattga aaaaggttta tgctgaatta cttgcacaat atccaccaat atctttgcac
    30121 catacttatg agctattctt gctatttcat atataggagt ggttatacct gtgacattac
    30181 tagctcctgt aactgtaacg agagatacat taccagcata atttttaagt atattctcta
    30241 attgacataa atcaagttct cctttttctg taattccaac aacttttgta ggaaaattaa
    30301 ctttaaaagg caggtaatta gccatatgct ccattgctgt ggtaataaca aatttatctg
    30361 gattttcatc tttaaaaaat tttgctaaga agtttattcc ttctgtagca tttttgacat
    30421 aaataacaga atccttttct tcgtctccat caataagttt gaggatagta gagcgtacat
    30481 tttcatattt taaagtattt ttttctgaga ttattcctgg agcattaata taagtaagca
    30541 aaggaatctc acagtttaag ttatccacta cgttttttaa aactaatgga gtggcagagt
    30601 tgttaaaata tattctttta acagtttcac cacttttagt tttaacttta aggtttgcac
    30661 cttcaatgta tttagataca tccatgaatt gcataaaaaa accccttatc taataaacta
    30721 ttctgttttt tattaaaaaa gctcaagttt taatcaagag cttgtttaat atatgttatg
    30781 tttttataag gggttttgtt aattaattct tgttgagatg tttattaaat tacacgaaaa
    30841 tgagctacag ttgggggaaa ctgtagctca cttgattttg ggggagatag gttgaactta
    30901 ttgtttatcc gtatcatatt tttagtatag tcacttattt taatttatat acattttttt
    30961 ataaatttta cataaaatgt taaacactaa ttagaaataa ttatgaatat gactaataaa
    31021 gttgtaaaaa tagtaaagaa attgattaga acataatgga aaatatattg tatataatta
    31081 gaaaaaaaga ttttatatgt tataaaagat gtgcaagtat aataatttta taaaaaatac
    31141 aaaatataat acaaataatt ttataaaaaa aattataaaa aaatttaatt tatataaatt
    31201 aaaaattata ttaccaatgt atatatttga gaaaagatta gtacaaagct ataatctgaa
    31261 tttcaataaa tatatatata attaagttga aacacttgaa aatactggaa aaaattgaaa
    31321 atagtttttg taatataaaa tgtcgattga ttttaaataa ttaaatatac ataagaaata
    31381 attaaatata tttcaatgaa aatatgataa aatatgacaa attaattgat gacaataaaa
    31441 aatattttgt tattgtagta ttatagggta aattgcaaaa tatatacgaa agtaaaattt
    31501 taaatattga cattaaatta aatatactat actatgtaag tgtgatgaga gaattttttt
    31561 agaggggatt tatagtgaat ataaaaaaga tatttaataa caatgtagta gtaagctccc
    31621 tagaagatgg cacagaaata attgtcactg gtgctggagt aggatttaag aaaaaagtag
    31681 gcgatttgat agatgaaaat ttgatttcta agaaatattt tgttcaagac gatcaaaggg
    31741 acaaatacaa tcaaatactt aataagacct ctattgaata ctttaaaatt tcagaagaaa
    31801 ttatagaaaa ggctaatgaa gttttaaata ctcaagtgaa tgattcaata atattagcct
    31861 taactagtca catagaattt gctgtccaaa gagaaaaaca aggtataaaa ttaccaaact
    31921 taatattgaa tgagacaaaa caactttata gggaagaatt tgaatttgga ttatgggcaa
    31981 ttgatgaaat tgaaaaaagg ataggaataa aattgcctga agatgaagca ggatatattg
    32041 ctattcacat aatcaatggt ttggaaaatt ctcaaaaaga tgaaggtatt aatatactag
    32101 agttttcaaa acaagttatt cagataattg aagaagtaca tggatttaaa ttggatgtaa
    32161 attcattaaa ttatactaga cttataactc acttaaagtt ttttgttcaa aggattctcc
    32221 gaaaagaaac ttacaatgat agtgatattg aagatatgta taagttagtg aataaaaatt
    32281 acaataaacc taaagtgtgt actgaagaaa ttgcagcatt ggtattagac agatttgaat
    32341 ataagattag taaagaagaa gaattatatt taatgattca cataaataaa ataacaaaca
    32401 gtggttgtta ggattgtaac tgataaagca ggcaaaacct aagtcattga gcttaactat
    32461 tagattaagt tttttgattt aggttttttt attagataca atcaaaatac agacagtgac
    32521 ttttaggatt gtaactggtt aagcaggcaa aacctaaatc attgaattta actattaggt
    32581 taagtttttt gatttaggtt tttttattag atacaatcaa atacagacag tggttgttag
    32641 gattgtaact ggttgagcag gcaaaaccta aatcattaaa cttaattatt aaattaagtt
    32701 ttttgattta ggtttttcta taaatttgat tatgttttta gataaaaata ggaggggaaa
    32761 attatgaaaa aaaataagtt aggtttatgg aacttcttcc aaatgttagg aaaaacgttt
    32821 atgttcccaa tagcactact tagtgtttct gggatgatgc taggacttgg ggcaggtttt
    32881 acagacccta agatgattga aatggttcca tttttaggga atgaatatgt taacttagtt
    32941 ttaaacttca tgttaacaat aggattattt gcatttaaca acttgggagc attatttgca
    33001 atggcaattc cactaggatt attaaaaaaa gaaaaagagt ttggtgcttt ttcaggatta
    33061 gtaggattta tagcaatgca tataggtaca aatttttatt taacaagagc tgatttgtta
    33121 gtaccagcag aacagatgtc aactaatggt caagctatga ttatgggtat acaaacatat
    33181 aatacaagtg ttttaggtgg tattgtagca ggattaattg tttatgcaat atatgataaa
    33241 gttagtaatt taaagatacc agaatcatta ggattctaca gtggaccaag attagttcca
    33301 attgttagtt taatagttat gagtatagtt ggattattaa tacctattgt ttggccacca
    33361 tttttcaatg cattccaaag tttaggaaga tggatttctt cagcaggacc attaggatat
    33421 ttttcatatg cagtggcaga aagagttaca attccatttg gactaaatca tcttgtaaca
    33481 tctgtattcc gttttacacc aataggtgga actgctgtta ttgatggaga aacgtacttt
    33541 ggtacattga acatgtttat ggcatatgta gaaaataatc agattatacc tcttgattta
    33601 gctggtaaaa tggaacaagg taaattgatg attcaatatg gattagctgg tgctgcattg
    33661 gctatctacc gtacagcaaa accagaaaat agaaaggcac ttaaaggact tttaatatca
    33721 ggagtgttga cagttattat aggtggtata agtgaaccaa tagagtttct attcttattc
    33781 atatcaccag cattatttgc tttccataca tttatgaatg gtctagcaaa catggtactt
    33841 ccatacttag gcgtgttgat gggattcaca ggagatttaa ttgcatttat aagttttggt
    33901 gtgttaagag gaacagctac aggatggcca atagcagtat tagtagcagt tttatatttt
    33961 gcaatatact attttgtatt taagtgggca attattaagt ttaatataaa gaccccagga
    34021 cgtgaggata aagaaataaa agtatctgaa ggaaatggtt caaatttcaa aaatttgtct
    34081 acatataaag gacaacaaat gatatctgct ttaggtggtc aatctaatat attatcacta
    34141 gataattgtg taactagatt acgtttaaaa ttacaagatg tatcattaat aaatgaggat
    34201 gcaattaaag aggctggtgg tatagcagtt gttaaattgg atgagcatac aatacaagta
    34261 attataggaa cccaagtgta ttctttaaga aagcagatgg ataaagctat ggaaggtcat
    34321 ttggaggcat gtaatgatta attttgataa aaaagtagac cgattgggta catattgtac
    34381 ccagtgggac tatgtagaag atagatttgg taagaaggat ttgcttcctt ttacaatttc
    34441 agatatggat ttagagtttc catttgaaat aacagaggtg ttgcaggaaa ggttaaatca
    34501 tagagttttg ggatacagta gatggaaaca tgatgatttt agaaattcag ttacgaattg
    34561 gtatattaaa agatttaatt gtagcgttga tagtaactgg atatattata gtccaagtgt
    34621 aatgtattca attagcaaac ttattgagat gttaagtaat gaaggagatg gaatccttat
    34681 aaatactcct gcatacaatg ctttttatga tgtgataata aataacaatc gtaatattat
    34741 aaagtcacat cttgtaaata ggaatggatt ctattcaatt gattttaatg attttgagaa
    34801 aaagtgtaaa aaatctaaga tatttatttt atgtaatcct cacaatccaa ctggtagagt
    34861 atggagtgag ttagaacttg ttaagatgat aggaatttgt aagaataatg atgtcaagat
    34921 aatatcagat gatatacaca tggatattgt atatgacaat agaatgacac ctatcttaaa
    34981 tgttgcaaag gactatttag attctgtatt catttgtaca tcagcgtcta aatctttcaa
    35041 tataccagca ttgactgggt catatgtgat tataccaaat gaaggtatta gaaataaatt
    35101 tgaaaatatc actagatacc gtgattttgt aaattcgcca gcaattctag caatattagc
    35161 cacaatggtc tgttatgatg actgcgaata ttggttagat gaactattaa aataccttaa
    35221 agagaatctt aaatatacga ttgattatat aaaagataat ttagaaccat tgaaattggt
    35281 catgccagaa ggctgttact ttgcttggat agatttttcc gaacttaaaa taagtggtga
    35341 gaaattccaa aaattattga tggatattgg agaagttgct attatgtcgg ggtctgtata
    35401 tggtgaagaa ggtgagtttt atttaaggtt aaatgtggca tgttcaagag aaaaacttga
    35461 agatggttta aataggatta aaaaaactat ggattatatt gaaaaaagaa ttttatagta
    35521 ggaagggaga tagttatggg atatttaaaa acaatggttg atgttatgac tactgaaatg
    35581 aatgccataa gatgtttaat agatgaagca ggaatagaat atgaaagtat agttagtgaa
    35641 attgcaaatt gtgaaggcaa agtaattttt atgggtgtag gaaaatctgc acatataggt
    35701 aagaaattgg cagctacatt tgctagtact ggtacaccta gcttttttgt acatgcaaca
    35761 gaggcagtgc atggagattt aggaatgatt gaaagtaagg atattacaat tttaatatca
    35821 aatagtggaa attctatgga agtggtaaac tgtataaaat atattaaagc aataggttct
    35881 aagacaattg catttacttc aaacagaaat tcagtactgg caaaagagtg tgattatgct
    35941 ttaatatatc ctgcaaagga tgaagcagac catttaaatc tagcaccaac aacatcatct
    36001 acaattactt tggttttagg agattctatt gcatgtgcat tatctaagag tagtaatttt
    36061 ggttcttcag atttttataa gtaccatcca ggaggaagtt taggtgagaa gttaaaaaca
    36121 gctaacaatg gataaaagca aaaaggagag tagtttttat gttcaaaatg tttaaaaaaa
    36181 aatcaataaa atcacccata tcaggaaaag taatagagtt atctaaaata caagatggtg
    36241 tattttctca aaaaattatg ggagagggtg tagctataga ttctacagga gacattgtat
    36301 atgctccaat caatggaaag atagtagtag tagcagagac taaacatgca tttgtaatag
    36361 aattagaaaa tggaatggaa cttcttattc atgttggttt agatactgta aatttaaaag
    36421 gcgaaggttt tgaggcattg gtgagtatgg gagaacaagt gaaggaagga acaccaatgt
    36481 tgaaaattaa ccgtcctttg attgaatcaa agggtatatc acttattact ccagttacaa
    36541 taactaatca ttcagagtac aatatgaata catgtaatgt aggcaatagt gttgaaggtg
    36601 ggaaagatac tgtaattgag tttaaataaa gaactaaaat acaaggttaa tatttataaa
    36661 tacctataaa cttatgtttt ataagattga ttgtatagat ttgttgtata aaaaagaact
    36721 ctttaattat aaattaagga gttctttttt attttgtaaa tattgtttag atttatatag
    36781 aaaaacactt agtaataaat agaataaata agtatttata tagctaaaaa tctaaatagt
    36841 tttgtttaaa tatattttta tattttgtaa tttcaaatta ataaataatt agatttgata
    36901 aacaaaaaat aaaaatgttg attatattaa taaactttaa tataatatat ttatgaaaaa
    36961 tgtaaactgt gaaatggagg tagtaacatg aaaattgaaa atctttctat tgatgatatt
    37021 aaacgaggct atatatttaa tgatgattta aattgttata gttgcattaa atgtacaaaa
    37081 acatatgagg taggagaaat atataaaata ggtaatagat tctttgaagc ttcaaaagct
    37141 attgaacttc atatggaatt agaacatagt gattatttag agcaattgct taatagtgat
    37201 tcaaaataca acacattgac tgaaaatcaa aaacaattat ttcaattatt tattagtgat
    37261 ttaccagata aggagatagc aaaacaggtt ggagtatcca catctactat acgccatcaa
    37321 aaatttattt tcagagaaaa agcaaaacag gctaagctct atttagcact atatgaatct
    37381 gtatttgaag ataaatctaa taaaagtagt actataatac caatccatga acatgctcga
    37441 atggtagatg aaagatatgt agtaactgaa gaagagagaa aacacatttt ggatacatca
    37501 tttgaaagta tgaatccttt aaaattaaaa gtattttctt caaaagaaaa gaaaaaggtc
    37561 gtaattttat ctaagatttt ggaacaattt gaacgtggga agaaatattc agaaaaggaa
    37621 gttaatcaga ttttagaatc tatatatgat gattttgcaa caattagaag atatctaatt
    37681 gagtatggtt ttatgagtag aaataaagaa tgtacaaaat attggttaac ataattaaaa
    37741 taataaattt tactaatgtg taatgttatt tttatctagg gggaggagtc aaatatgaat
    37801 gatgaattaa aatctatttt atacaataaa ggtgtggaca ttgttcgctt tgttgatata
    37861 tctgaatttc caataaatca aacgcaaggt ttttctaaag caattttatt ttgtataggg
    37921 ttatcaaaaa aatttattac agatatatac aataacttac ctacagatag tgatgagttt
    37981 ttagaaaaag aggagaaagc agaagaatta gctgactgga tttcagaata tattcaaaat
    38041 aaaggatata gagcgtattc tcaatcggag aaaaacaatc tagaacatgg atattttgaa
    38101 aaagcctata ttaatccaga aatgcaatca gggattagtc ctttaccaca taagacaata
    38161 gcaaatatta gtggcattgg atttatggga aaaaataatt tgtttgtaac agaggaatac
    38221 ggatgtgctt ttagcatgtg tacagtactt acagatgctc caatttctgt tgaaagatat
    38281 cctttgattg attcaaaatg tatggattgt aatgtttgtg tagaaaactg ccctgcaaaa
    38341 gctatacatg gaaatgagtg gactttgcca ggaaaaagag agtctattat tgatgtttca
    38401 aagtgttttt gtgtattgaa gtgtatgatg agttgcccat ggtcattaag atatgcaaat
    38461 caaaaataat tttactagag aaggtattaa attgaatatt ataaaatttt taaaatgtaa
    38521 gattatataa gatttttcaa aataaaaatt tgtatagaac actcagaaat gagtgttttt
    38581 ttattggaat taaattatat tgatacaaag tttaactatt ttaatcatta tataaaattt
    38641 gtattaaaaa attaagaata acttggtaat agtgaaaata taatgagatt ataattgatt
    38701 tataatataa ctataatgat gttgtaaaat gaaaattgtc atttcaaaat tcccaaaaag
    38761 agtaaaagtc acttcggtta tagtcaaaaa attttttcag tgaaaagaat ttagatttaa
    38821 aagggaggaa ttaatcatgg aaattgaaac taaaactccg gattggatta atgtactaga
    38881 attaaacagt aaaatagata ttactgggaa atatgatgta agtaatatta tacaagatat
    38941 tgtctctgat aagtcactag aaggttccat tatatatttt ccaaaaggta attatttatt
    39001 tgagaaaggt attaaaatta gtcaacaaat aacacttcaa ggagattctt attatggagg
    39061 agataatcaa gtatcaaatt tagataaaaa acaatcaatc ataggaacaa ccaattttat
    39121 aactcgagga gtttctaata tgagtattat tgcattgaca ggaacaagtc aatgtatcaa
    39181 aaatattaat ttttattatg atagtcatga tatagagaaa ataccgccta aaaatgtatc
    39241 tgctattaca gaatatggag aaacacaagg actatctcat tttgaacacc tgtttatttc
    39301 tggattttca gggataggga ttgaaattcc atactattca actggcaatg atataattgt
    39361 tagttcatgt ggtcttggta tgaggcttgg agagaagtca atgctttcta gtagcaagat
    39421 ttacgaatgt aaaaatggaa tggagattac tactggtgtt agcttaaata atgtgagaat
    39481 agaagaaata aaagaaatag gtattaataa taaaggattt ggttttaacc tgattatgaa
    39541 tcttatggtc gaccaatgtg gatattgtgg atttatgttt gaaaaaatgt gctatagcca
    39601 gataactgcc agaattacta gatgcggtca gtattataaa agtgttgatt ataatgctta
    39661 tgagaatatg gaagatagaa aagaaaaagc ttattccatt ttttatggag atattttaga
    39721 aagttgcaat attgtattga tgaatagaaa tattgatacc ttagaaagtg attcacttaa
    39781 tgaacataag atatatgtaa tcaaggcaaa tgaaacaaac aatgtaatgc taacatgtta
    39841 tgctgaagca gataacttta tacaatgtgc aaagggcaac ttgctgttag aaaatggtga
    39901 aaatacttat aaattttata atggtgagat ttgttctgta ggaggtgttc aaatttctga
    39961 tatagatgaa aaagatttaa tcaaaataat agagaacact ttgtatatag atgataaagg
    40021 taagtattta atggttccta gattaaaaaa gaatactgta atatattcag tactagattc
    40081 tacagaagaa ataaataaat tacatggtgg aatatgggaa cagattgatg taaaagtatt
    40141 agctggggaa tccatgtact attataaaaa gataaaagat taaattatca aactaggagg
    40201 tagtgattaa tggaagagtc tataataatt aaagatataa gtggctggat taatgtactt
    40261 gattatggaa tttgtaatga tgaaacaaaa gatgtaagtt ttaagttgca agagattatg
    40321 gatgctgtac cagaagattc tattatatat tttccaaaag gaaaatactt atttgaaagt
    40381 ggtgttaaga ttaagaaacg attaacctta tgtggagatt cttatatttt agcgaatgtt
    40441 cctaaaaata ctgctggagt aacacagttt acttttaaag gaaagaaaaa tcctaaaagt
    40501 gaaaatagag caatcataac agcaaaaagt gtaagacact gtattaagaa catttgcttt
    40561 tattcagata gttgtgatag agatatgaca tctaatcatg aacctccaac agatggaaaa
    40621 cctagatttc atcataatgt aattataaat tatagaaata tatctgctgt tatatgtgaa
    40681 gataaacagg gagaaccagg tcattatgaa aatctatctt ttagtggttt ttctggaatt
    40741 gcacttgata tgcctaataa ttctacagca aatgatatta caatttttac atccggactt
    40801 ggaattagta caggggaaaa ttcaacaatt gctaacagta aggtttgggg ctgtgttgat
    40861 ggaatgataa tttctactgg aacttttata aatggtatga gggtagaaga aataaaaaaa
    40921 gttggaatta aaaatattgg tagaggttta aattttatta caaatatcac aattgaccaa
    40981 tgtggatatt gtggagtttg gtttgattct atatccaatg ttcagatatc aggaaatatc
    41041 acaaggtgtg ggcagtacta ttatgatgta agctatgata attatttaat gttggataat
    41101 agagttaaag aagcatattc tttattctat ggtaatttat tggagtcaag taatatagtt
    41161 ttatcaaata ccaatgaaga taattgggaa gatttcaaag aagataagca taaggtgtat
    41221 cttatagaag cacttaaaac caagaatgta ctattaacat gcaatataga tgctactgac
    41281 tggattgtta agtcagaaaa aggaaattta acgtacaata atatgcgaca aactgttata
    41341 ttttacgatg gaaaactaag tagtatcaat ggaattggta tatctgatga agattatggg
    41401 gataaagtca agataaaaaa aggaaatata tatataaata gtaatgataa ggatattaag
    41461 atgcataaac cagaggtagg tgacattatg tcaacaatta ttaaagataa aagtattctt
    41521 tctgctcatt atgggggaac atgggagaaa attggtgaaa aaatagagtt tggaataact
    41581 gtacactatt ataaattgat agagaaataa gtaaatacgt agtatttgaa tagatgtatt
    41641 ttattggaga gttaggacta tagttttaat ataaatggtt tggtaatagc atggattgaa
    41701 taatataaaa ataatataaa aaattaattt gattatgtaa atttctatga agtagtaaaa
    41761 ctgtgacttt agtcatagga ggttcaaact aagtaaaagg gaaaggaata tataatatta
    41821 tggaaggaag aactgggatt aaagatggaa gatggattaa tgtagtagaa agaggtatta
    41881 aaaatgatgg ttcgtacaac ataggtcctg ctttgcagga tattattgat gaaatagaaa
    41941 cagatttttg tgtcttatat tttccaaaag gtaaatacct atttacaagt ggtgttaaaa
    42001 ttaataaaga aattgtattg caaggtgatt ctaattcatc tacaggtact acacaattta
    42061 taactcgtgg agtagaaaat atgagtatta ttacattgac agggaagaaa caatgtatta
    42121 aaaatataaa tttctattct gatagttgtg agatacaggt aaataaagaa ccaccgacaa
    42181 aaggtaatcc taaatatcat tatgagatga ttattaataa gaatgaaaag aatgttgaga
    42241 tgaataatgt atcagcaatc ctgtatgata acagtaagaa tatgattaaa ggtctaggtc
    42301 attatgaaaa tatttatata agtggttttt cgggtacagg aattaggata ccatattact
    42361 caattgtaaa tgatattaca gtttcatctt gtgggctggg tattgataca ggaatagaca
    42421 caattatttc taatagtaga atatctaagt gtcaaaatgg aatgaggatt agaactggaa
    42481 ctagtataaa taatgtaagg attgaaaaaa tacagaaagt tggtcttata agtagtcaag
    42541 ttaaggggta tgaggggtat ggaagttata aaattaataa tattacgatt gaccaatgtg
    42601 ggtattgtgg cttttcattt gattcaatga aagatagtta tttttctggt attataagaa
    42661 ggtgtggtca gtattattat aatacagatt atgacacata tttaagtatt aaagatagag
    42721 tagaagaagc atattcttta ttttatggaa attattttac agaatgtaat attgatttag
    42781 ttagtgataa taaggataac tgggatgatg gcttagaata taaacataaa gtttatgtat
    42841 ttaaaaccct tcaaatacca aaattaacat tgagatgcaa tatagatgcc tatgattata
    42901 tcgttaaatc ggtacatgga ggaggtaatt taatgttaaa aaataacttt aacaattata
    42961 tatttattga ttcatctaat ccagaagtta ttaatggaat taattttaat tatcaaaaga
    43021 atggaaactt gttaaggtta aataatggta aattaagtta taaaaatgga aaggaagaaa
    43081 cagctatatt cagacctaat tatggtctta ttgtagcatc aacagattca gaatgtgaac
    43141 aaatagaggc tacctatgga gaaaaatggg agaagcttgg ttctgaagta attggagaag
    43201 aaacggtata ttattataaa catcatgaac cagataaaac aaaccaaata caataaaatt
    43261 tgtattatat aatgatataa agttttaata tatagtgttt acctttaatg taatattggt
    43321 atatttgtat agtattaaat ttgttaaaaa gtaaaattgt agggtgcttg aaaatagcac
    43381 cttttttagt ttcattataa aattagtttt gaaagtttag gaataatgta tatttatttt
    43441 taaagaatta taaccttatt aaggatattt taaatgctag aaatgaatca gtaaatcata
    43501 ctggaattat cttaaatgtt ttgattaaat taagtattta gagctataat tatattaaaa
    43561 atatattaga acataattat attactatgg aggttaaata tgatagtaag tgtgagtaga
    43621 agaactgata tacctgcttt ctatagtaag tggtttttta acagacttga agaaggtttt
    43681 gtttatgtaa ttaatccaat gaatccaaaa caggttagta agatagagtt aaatccacat
    43741 actgttgatt gttttgtatt ttggacaaag gatgtaactc caatgttata tgatttaaat
    43801 aaattaagag actataaata ttattttcac tatactataa catcatatgg aaaagaagta
    43861 gagacatgta ttttagataa aagaaaggta atagattcat ttaaggaatt gtctagaaaa
    43921 ataggcaaag aaagagtaat tttaagatac gacccgattt tcttaagtga aaagtacaca
    43981 gtagattatc atatcaaagc atttgcgagt ttatgtaatc agcttgatgg atttacagaa
    44041 aaatgtataa taagttttat cgatttgtat aagaaaacaa aatttaatac taaagcatta
    44101 catataaagc caatagaaat tacagaaata gaaacattat caaaagagat ttctaagatt
    44161 gctcataagc atgggataat acttgaaatg tgttctgaag aatataattt aagtaaattt
    44221 gggattggaa aaagtaagtg tattgatgat agattaatat caaaaattat aggatgtgaa
    44281 gtagaggtaa aaaaagatag tacacaaaga gatatttgtg gatgtgttaa aagtgtcgat
    44341 ataggacaat acaatacttg cagacattat tgtctgtatt gttatgctaa ctttaattat
    44401 gcaaaagtag aagaaaactg taggctttat aaggaagata ataaattact catagatact
    44461 ttaagagatg atgcaaaaat aagcattaga gatatgaaga ctattaaagt agataagaat
    44521 aaacaaatta gtatatttga ttaaaataaa tatactaatt accttaatat attaagaata
    44581 tagatacttt tgataacaaa attaaactta atagatattt tctatataag aaagatggtc
    44641 ataatatgtc aatttgacca tctttttgat ataattaaaa cacaaataat ttagtaacaa
    44701 aggaggcaga acttgaattt attaaaaaaa tatcctatac ctattgcaag tttgatttta
    44761 tcaattttta ctttaggtaa cttattacaa tcttatagtg aatcattacg taatgtaatt
    44821 ggatttatag gatttatttt gtatgcaatt tatatagtca aaataatatt acttagaaag
    44881 ggtgttaaag agcaattaga gaacccttta atatcaagta catttccaac tataacaatg
    44941 gcaacaatga tatttgctac atatataaaa ccattatctt tagaattaag tattatgatt
    45001 tggagcatag gaattgtggg tcatcttgtg ttaatagtct tatttagtaa gaagttctta
    45061 gttaaattct caataaaaac ggtatttcca tcttggtata tagtatatgt tgggatagtt
    45121 gcagctagtg ttacggcacc agcatttaat caacttttga ttggcaaaat tgccttttgg
    45181 ataggatttg tatcttatat agttcttata ccagtaattt taaagagagt atggataatc
    45241 aaggaaatgc ctgaaccatc cttaccaagt atagctatat tagctgcacc agggtcacta
    45301 ttattgtctg gatatattaa ttctttttca gataaaaata atgtagtatt atacttgtta
    45361 ttcatattat caattgtatt ttatattata gttttgggat atttaccgaa attattaagg
    45421 ttgccttttt atccgagttt tgctgcattt acattcccta tggcaataag tgcaatgggt
    45481 atgaaactaa tgaatggtta tttaactaaa tcaggtcatt ttataagttg gatttcatat
    45541 gcttctaagt tagaagagat aattgctaca gtgattattt tatatgtttt agttttgttt
    45601 attatatatc ttagtaaatc tgaaactaca tctaaagcta aataagaatt attaaatatg
    45661 tgtatttaat aggaatattg atataaatat atgaagataa gataaaccat agaaacttaa
    45721 tttagcttaa ttttattgga ggaaaacaaa tgaaaacaaa agaagaatat ttaaaagaag
    45781 ttagaaacat atcagaagaa tactttagaa aaggagagtt tttttgctct gaagcagttc
    45841 tccagacaat aaatgatgct ttaggccaac ctttaagtcc agagataact aagttagcat
    45901 caggatttcc gataggactt ggaaaggcac aatgtctttg tggagcaata tctgggggag
    45961 agatggcttt aggtatagta tatggaagag ttcatggtga agctatgaat ccaaagatgt
    46021 ttgagcatgc taaaggtttg catgattata ttaaaaaaga gtatggtgca acatgttgta
    46081 gagctattac aaagaaatgg gatggtgata actttatgtc tcccgaaaga aaagagcact
    46141 gtattaaaat aacaggtcaa gttacagagt gggttgcaga taagcttata gaagatgaaa
    46201 aacttaatat caaatagtgt aatattagtt ggtgaattta taaagttaaa tttacttata
    46261 gtataagata cttgatattc tcgtattgat agaaaaattt atagcatatg tatttaatga
    46321 aatatactta tatttagagt gtggtttaat ttcataaata catatgctat tattttaagt
    46381 atataagcaa atttatttaa ataaatagaa acagttaatt tatatgtaca aaactatata
    46441 tgattagtgt aaataaatac ctattttata atactcaaca taaagacacc agacatgatt
    46501 agtattatac caataaaaat agcaagccat tcttttttgt tcttcttttc tttaaaaaat
    46561 ataatccctc ctaaagtggc tactatcaca caactctgag agatagaaaa acttattgta
    46621 actcccaatg tattagtcgt tatgaacata cctaaatttg ctattgacca caatatacca
    46681 gtaattaaat tgaataaaac attttcccta tatacaatct ctttagaaaa atacttgaca
    46741 ataatagatg aagttatcaa cataccaaca gattgaggta atataattct atatccttca
    46801 attaaaaata tttgattagt tacaacatat aatgataaaa atagagatga taataataca
    46861 actccaacac attttaacat atttttatct gtagattttt tagtttgata atttgtgaga
    46921 agtataccaa gtattataca taatattgat aaagaaccaa tcagtaacat tttagaactg
    46981 gtccattcat taaacaagat tacagctaat aatgtcgtaa aagttaattg tgaaccattt
    47041 gaaattggca ttactttaga tacactagca atttgaattg ctttaaactg cattaattgt
    47101 cccaaactcc agaatatgcc agaaatcata cttatacaaa atgaaaaaaa tgtaatttca
    47161 ggatgtataa ccagagttat tatagtggaa aatataaacg cacttatgga tgtacctaaa
    47221 agctgttcat gaggagaact tttctttaga tttgcaacta tgggcatcaa tccccatccc
    47281 attacaggaa gtaaagcaat aattattgtc agcattaaac tatttccttt catattaaat
    47341 ttagacagct tttaatttat catctaaaat taaagtgttc aatacataaa aattaccgta
    47401 tttaatcagg aaatattagt agttttttag aaaaacattt tccattaaaa taaagacaaa
    47461 gggaaggagt aaaattgaaa atgttaactg atatgattca aaatcgtgaa attaaaataa
    47521 taaagttttt attaaaagaa ggtcatacaa ctgtaaaagc aatagcagat gatttagatg
    47581 tttcagaaaa aacagtttca aaatctctta aagaagtaga agcagtgctt aaaaagatag
    47641 gtctttcttt aataagaaaa cctaagatag gtgtttatat tgatggagat ttaaaaaaaa
    47701 tacttcctta cctagataat aaaggaagtc aaattcctac aaccagagag gagagagtta
    47761 tctatatata ttcagtactt ttaaagagta atgattatat tactatacaa caactttctg
    47821 atgaactata tataagtcgt ggaactattg aaagggattt agcagaagtt gaaaaactgc
    47881 taaaaaacga agggatttcc atatataaga aacctagtaa gggaataaag ttaaatataa
    47941 gtgaaagaga taaaagacaa cttactgcta agtttataca taaattttgg agtagaaact
    48001 ggtatattaa gcaagagcaa gaaagctttt atcaagcatt tgaaaagata caagcagatg
    48061 taaatggtat tttttcggaa gatgatttat caataattat tgatattctt aggaatttca
    48121 gcagagaaag aaaatttgag ttctctgatt atgaatttca gtcattagtt attcatttgg
    48181 caatagctgt agagagaatt agaaaaggcg aatatataga agaaagtttg tatactggta
    48241 atatagaaaa taatcaaatg tcaaatacca attatttagc aaaacaatta gaagaaaaat
    48301 tttcaatatt attaccaaaa tctgaaattg gatatataaa tttacattta gtagcgtctg
    48361 accaacatag agatactaat gaactaaaaa atacttcaac taatccttgt gagacaagta
    48421 caaataatat atcaaatctt cgggaaatta taaaaaatac attgtatgag acagcttatg
    48481 acaaggattt aattgatgga ttaacttcac atgtacattc atcaataaat agactgaaat
    48541 atggacttag tattaaaaat ccatatgtaa atacaatcaa acaaaacttt tctttatcat
    48601 ttgagcaagc tttagattta aagaaagtaa ttgaatttat atatgatatt aggataaatg
    48661 atgatgaatg tgcttatata gcattacatt ttgaagcttt tagagaaaga atgaaagaac
    48721 ttccacaaaa tattagagta attctagtat gcagtacagg attaggttca tctaggttat
    48781 tgtctgcaag aataaaaaaa tactttccaa tgataaagat tgaaaaagta ctttccgtac
    48841 aagaattagt atccagtaaa attgatgcag atttagtaat aagtactatt tatttagagt
    48901 tagaaacaat tccaaccata gtagttagtc ctattttaaa tgaaagtgat ataagaacct
    48961 tggaaagaaa tatacaaaat gtttcaagtt atacttctaa gaagtataaa tctttcagaa
    49021 acttaatctt tgaagaaaat atattgttga atattgaagc ttcaaactat gaagatgcaa
    49081 ttaagtatat aacagataac ctaataaaaa aaggttttgc aaaagaaggt atagctaaaa
    49141 gtgcaattga gagagaaaat ttatcttaca cttctttcca atcaatagct acacctcatg
    49201 ctaatcctag ttatattaaa aaatctaata tatctgttgc aacgttaaaa aatcctatta
    49261 catggggaaa tgaaaaggtg gaagttattt tctttatttc attagaaaat gacaaaaacc
    49321 tagagcttga tgaaatatat gaagtttttt atgacttcat tgacaataaa aaaaatataa
    49381 atgacatatt aagtgcaact tccacaaagg aagtgtacga tttgctagtg gaggagagta
    49441 tatagtgaaa atatcagatg tattgaaaaa agagcaaatt gtttttaatc ttgatacaaa
    49501 tacaaaggaa gaaacaataa aaaaattaag tagtatattt gttgaaaatg ggattgtgga
    49561 caatgaagaa gaatatgtta agtctgtttt ggaaagagaa gaacattcaa ctacaggtat
    49621 tggtaatggt attgctattc ctcatgggaa aagtaatgct gtcaaaaaat cttctataat
    49681 atttgcaaag actaagcata agattgaatg ggatgcttta gatgaaaaac cagtagatag
    49741 tattttctta ttggctataa gcaatattga taaggatagc aatcatcttg tactattatc
    49801 taaattagca actaaactta tggatgatga caatgtagat gcactaaaat tagccaattc
    49861 agaacaagaa ataatcaata tatttagtga agaaggagag atgtagaaat gaaaagaaaa
    49921 attatagcag ttacagcatg tgcaacagga gttgcacata catatatggc agctcaagcg
    49981 ttaaagaaag cttcaaaaaa gatgggtcac cttataaaag ttgaaacaca aggagctaca
    50041 ggaatcgata atgagttaac tacaaaggat gcacaaattg cagaagtagt aatatttgca
    50101 gtagatacta aagtcagaaa tgctgaacgt tttgagggaa aagaaatact agaagtacca
    50161 gttaatgcac ctataaagga tgcagagaaa gtaataaatg atgcactaaa gttaattgac
    50221 actaaataaa tggagggaaa tgtaatgttg aaaaagatag tctctgagtt aaaaaagcat
    50281 gtcttaactg gaatctcata tatgattcca ttagtaattg caggtgctat gataatggcg
    50341 atatctcgtg taggtggttc tttctataat ataccagata tatgggatgc taaatatgca
    50401 gaaagtgcta gtagtattgt tagattatta catgatttag atgggtttgg aggtactgca
    50461 ttaggattaa tgtttcctgt aattgctgca tttataggat tttctatagc tgataaatta
    50521 gctattgtac caggtcttgt tggaggtatg attgctaaag atataggtgc aggattttta
    50581 ggagctttgg cagttggtct tatagcagga tatacatgtt tgtttattaa aaatcatgtt
    50641 aaattaccaa aatcagcagc ttcaatagta ccaatattta tagtaccagt atttgggaca
    50701 ttaatcactg ttgtattaat caattatgtg ataggtatac cttttgccac attaaatact
    50761 ggattagaaa attggttaaa tggattatct ggtacaaatc agatactaat ggcagctatt
    50821 ataggggcta tgatggcagt tgacttaggt ggaccagtta ataaagcagc tttaacaaca
    50881 tcacttgcat tattaacaag tggaatttat gcgcctaaca ctgctgcaat ggtaggaata
    50941 gttataccac cactaggatt gggacttgct actatactag caaaacaaaa atataataaa
    51001 cagttacgtg aagctggaaa atcatctctt ataatgggtt taattggagt aagtgaagga
    51061 gcaattcctt ttgcggtaga atctccatta aaagtaatac cttcatgtgt aattggaaca
    51121 gcaattgctt cagctatggc agttggttta ggttcagtaa atgcaactcc aattagtgga
    51181 ttttatggat ggtttacagt agagaattgg ccaatgtatg tgttatcaat agcagttgga
    51241 acagtaattg tagctggatt agttatagta ttgcgtggaa atccagtgat tgaggatgat
    51301 gaatttgaag atgatgattt tgatgaagca gagtgggaat cttaaaattt aataactatt
    51361 taagacgtgt tataagctat attcaatatg aatcttatac taaataaagt gttaaacatt
    51421 cagtttagac ttaaatataa aagataaaga acagaggaga ataaatgata aaagcacata
    51481 ttgttaatca tacacactgg gatagagaat ggtattttac ttctggagat gcattagtac
    51541 ttagtgaaca actatttaca gatgtaattg atgaattaga acgtaatcca gatgtaagtt
    51601 ttgtacttga tggacaactt tctattttgg atgattatgt acaattacac aaagaaaaaa
    51661 tagaaatcat taaaaagtta ataaaagaag atagactaca tattggacca tggtttactc
    51721 aaactgatgc attctttgct agaggagagt ctattttaag aaacttaatg attggaattt
    51781 ttgaaagtaa aaagtatggt aagtatatga aaattgggta tttgccagat acatttggat
    51841 ttaatgcaca gatgcctata ctattaaagc atgtaggtct tgataatata ttcttttgga
    51901 gaggtataca tcttggtaaa caggttcaat caccatattt taagtggaaa agcttaaatg
    51961 gagaaagtta tatatatgca gtaaatatgc cacatggata tggaactggt atgcttttag
    52021 agccttcatt aaagtatgtt aatggacgct tagacccagc tattgatttt attaaatcat
    52081 atactgatgt agatgaggtg ttaatacctt ctgggaatga ccagttaaat ataataggtg
    52141 atttcaaaaa taaaattaaa gcgattaatg atatcggaaa gtattcatat ataacgagtt
    52201 catatcaaga gtttttaaaa tatataaagt ccatagaatc actagaaagc tatagaggag
    52261 aatttagaga acctgtatta gcaagaatac ataaatcaat tggttctagt agaatggata
    52321 taaaattagc atgtgataaa ctagaaaaca agctgattaa aagaatagag ccattattag
    52381 taattgctaa aaagagtaaa attgaaataa gcaatcagtt acttataaat acatggaaaa
    52441 aacttttgga aggacaagca cacgatagtt tagctggatg tgtaactgat actgtaacag
    52501 atgatattct tcaccgtata agagaagcaa atgaaatatg tgacagtatt gaaaatacta
    52561 ttgtaaaaaa gatttcagaa gggcttaaat tatctaaaaa tgatatttta gtatttaata
    52621 cagaagctaa gcgttttaat ggatataaag agatacaagt tgtaagtgat agtaaaaata
    52681 tttattttaa agataattta gatgctacta taattgaaga aacttatgta aaaccgagag
    52741 aaaatgtatt agaagaaaca cctgctggta atatatttat tgaagaacca ggatattata
    52801 tattaaaagt aagaataaat gtacagcttc ctgcacttgg ttataaagtt gttagttttg
    52861 aatcaagtga taaagaaatg gtgtcactta ataaatctaa tgatgctttt atatctaatg
    52921 ataattataa gataatatat gaagatggaa gcttaaattt acaacttaaa gatggaactt
    52981 acatatcaaa ctttttaaca ttaaaagata gtggtaatgc aggtgatacc tatgactttt
    53041 ctccactaaa aaatgatgag gatataaaac tttcgtttga taaagtgtat acagaaaaag
    53101 ctttaggata tgaaaaaatg gtggttaaag gtactacttt actaccactt acgttagaag
    53161 atagaaaaaa caaatatctt aatgggaaat taaatgtaaa agtaagtatt gtcttatcca
    53221 aagaaaatcc attgatggat gtaaaacttt gtgttgataa tacgatatat aatcatagac
    53281 tacgtgttca tataaaaact gatataaaag ataataaaaa catagcatca ttgccatttg
    53341 gatatataac aagagaaaat ggagttttag acaactggga agatatttac agtgaaatgc
    53401 ctatagattt agaacctttg gaaagtaata ttactctaac aaaccaaaat agaagctgta
    53461 ctatatttac taaaggaata aaagagtatc aacatattga agatgaaatt gcattgacct
    53521 tacttgctac tacagatgaa ctaggaaagc ctgatttatt atatagacca ggacgtgctt
    53581 ctggtgatac aactaaaaaa ggtcacataa gaattaaaac agataaagct caaatgctta
    53641 agaaattaga attttcattt gcaatatata tggattctaa atcatttgat gaattggaaa
    53701 ttgcgaattt aacccacaat tatctaaggg aatgtgtaaa ttatcaatta caggattaca
    53761 atttcttttt atatcgtata gataataaga ttcaaaaatc aattgtcaat aaaactgtaa
    53821 gtagagaatt agaaataata tctttaccag aaaactatct tatatcagca tgttatcctt
    53881 cttattacag taaagataaa tttataataa gagtggaaaa tccaagtagt aataaaatga
    53941 tattggatga gcaaatattt aaaaatagaa atgggaaaat tgtaaatgca atagaagatg
    54001 tagaagagga acaggtatat gaaatagcac cttttgacgt tatttcaata ttattggatt
    54061 tataagtgta aaagtaagtt tattgtttaa agtctgacag atattaatct gccagacttt
    54121 ttaatttgta taaatttggg taaatattaa tgaatggttt tagtatttaa gtatgaattt
    54181 agtatttaat atagaattta ttgaagtaga ataattagtt taacaggata agcagtttaa
    54241 ataaagaatt attatattag agtgatttta tatataattt aagataataa aattttaata
    54301 aaatgagtta aagattgtat attaatagag ttgatgtagt tacaaaaaag ttaccaattg
    54361 ttatgtattt acaaaactga tatattaatt acataaaatc taaaatagtt tgtaatagga
    54421 gtatatataa taaaaatttt aattaaataa agctaggtat atttataata ttaataaata
    54481 tattgctata aaagtttgtt taataaatta aataaagaaa agaggagaat aaaatgtaca
    54541 acatagatga tatgatatat aattgtccag tagaagcttt atcaaatatt ttaggtaaaa
    54601 aatgggtggc tataattata tggaaaatac aagaagataa aaaacgattt ggagagctac
    54661 aaagagctat accagactgt agtaagaaaa tgttagttca acaactagat tttttaattg
    54721 aacaggggat tatagtcaac caaaaaaagt tggttaataa tgttgtagag tcaacatatt
    54781 ttttaagtga atcaggatta cgattgcttc ctgtcatgga aaaaatgatt atgtggagca
    54841 ataaaaattt aaattgtgat aaatactaaa atttactctg taagtaatga aaatttaatt
    54901 aagctatgag tagaaaaatg tattaaaatt acataatttt ttagttagat tttaatttag
    54961 aaatgggatt gtaatattgg aaataaaata aggaggaatt ttaatttgca aaatgtaaat
    55021 ttatttttag tatttataga aggtatagta tcattctttt caccatgtat actgccaatt
    55081 ttgcctattt atttgagtat attgtcaaat agtagtgtag aaaatttaaa agaaggaaag
    55141 acgagtttta taggaagttc tttatttaaa aatactatat tttttgctct tggaatctca
    55201 acaacattct ttatattggg ttcatcagta aaagtattga gtatgttttt taatgaaaat
    55261 aaagatttaa taatgtttat tggtgggatt ataattatta tcatgggatt attttacatg
    55321 ggaataatta aatcttcaat attgaataga gaaaaaagat ttaatgttaa gtttaaagaa
    55381 atgaaagcaa taacagcttt tatattaggt tttacattta gttttggatg gacaccttgt
    55441 attggtccaa tattggcatc tgtattagtc atggtttcaa gttcaagtaa tcatcttagt
    55501 gcgaatcttt taatagcagt atatactatt ggttttattt tgccattcat aattacagct
    55561 atgttttaca gtaaactatt taaaactata gataagataa aatctaacat ggaaattatt
    55621 aaaaaaatag gtgggattat acttatagta tcaggaatat taatgatggt aaatggattt
    55681 ggaagtataa gcaaacactt taatacgtca caaaatagta aaattgaaag caagcaagaa
    55741 gaaaataagc gagaaaattc tactgataaa gaagaaaatt ctgatggtaa tgatagtcaa
    55801 aaagactcta ataatgacaa taatgataaa gggtctaatg atgaagatag aataaagtct
    55861 attgatttta ctttaacaga ccagtatggt aaaacacata aattaagtga ttatgaaggc
    55921 aaagttgtat tcttaaattt ttgggctaca tggtgtcctc catgtaaaga agaaatgcct
    55981 tatatagaac aactgtataa agactataat aaaaataatg atgatgtagt aattttagga
    56041 gtagcttcac ctaatttagg tagagaaggt tcaagggaac atgtagttaa cttcttaaaa
    56101 gaccaaggtt atacattccc tgttgtactt gatgaagatg gagcattagc atatcaatat
    56161 ggaattaatg cttttccaac tacatttata attgacaagg aaggatatgt aactcagtat
    56221 attccaggag ctatggataa ggcaactatg gcatcattta ttgaaaatca gagaaataaa
    56281 taaaagtatt taagtataag tttataaatc aatttaaggt tacaaaaaag tgcctaattg
    56341 taccacctaa ataatcttgt tatagtaaaa gtataaacaa tacaagaaag ggttgaattt
    56401 tatatgaaaa aaacatttga tgctataata ataggatttg gaaaaggtgg aaaaacatta
    56461 gcaggggatt tggcaaacag gggattaaaa gtagctttaa tagaaaagtc aaacaagatg
    56521 tatggtggaa catgtgtaaa tgtggcatgt ataccaacaa aaagcttaga aaattcagca
    56581 aacagcgtaa aaacaaagaa tataaattct tgggatgaag tacaagctga atatgagaaa
    56641 gctatagata aaaaagaaac tttaattaca aaactcagag aagctaacta taataaatta
    56701 aattcaaatg agaatgtaac tatattcaca ggaatgggaa ctttcattga tgaaaaaaca
    56761 gttcaagtca aaactgaaaa tgaaatttat gagttagtag cagataatat atttattaat
    56821 actggttcaa gaccatttat acctaatatt aagggaattg aaaataagaa tatagtatat
    56881 gatagtgagt ctcttatgaa tctaagaact ttacctaaaa aaatgacaat tataggagct
    56941 ggatttatag gtttagaatt tgctggtatt tatagttcat ttggagcaga agttacaata
    57001 ttaaactcta ataatggcat tttaccaaat gaagatgttg aggattcaga agaaataata
    57061 aaattacttg caaagagaaa tgtaaaaatt gttaataatg caaatataaa agagattaaa
    57121 gaagtttctg aattagcaat agtagaatat gaagtagatg gtaaatctaa agaattaaca
    57181 agtaatatga tacttgtagc tacaggaaga aaagcaaata ctgaggagct agggctagaa
    57241 aatgcaggta tagaattaaa tgaaagagga tttattaaag tctcagaaac tcttaagact
    57301 aataaagagc atatatgggc tataggagat ataaatggag gtccacaatt tacttatatc
    57361 tcattggatg attatcgcat agttattaat cagttgtttg gagataagac tagaacaact
    57421 aatgatagaa agaatatccc aaattctata tttataagtc cagcattttc aagagttggt
    57481 cttaatgtta aacaagctaa agaaaaggga tatgaagtat tagtggcaaa gatgccagta
    57541 gaagcaattc caagagctaa acagattggc aaggcagatg ggtttataaa aatagtgata
    57601 gataaaaaat ccaataagat acttggagct agtatgatat gtgaaaattc aagtgagatt
    57661 atccatctta ttcaattagc tgtagattta gaagtagagt atacatattt aagagaccgt
    57721 gtttatgcac atccaactat gacagaagct cttaatgata ttctatctcc taatatgata
    57781 aaagaagtat aacataagtt taatatataa acctaaaatt atcattataa gtagatttta
    57841 gaaagaggct atctcaaaaa atagagataa gtctcttttt tactgtttaa atgataaaaa
    57901 tatatttgat tttataaaag aagattatct tatgaactaa aaagtttatt ttaaaacact
    57961 acctatttat gttataaact tataaatata atatagaatc tattattctg tattattaag
    58021 tggggttaag cgttataatt aattataaat attgaataat ctaaatggat aagataatgg
    58081 tattaaaaat tatcttaaaa ggtgaaataa tctgtattta atgtagtaca gttatatctt
    58141 taaagcaagg tggtgaaatg atataaataa gatatctaaa agagggtttg atgatagtga
    58201 taaaagatgg ttttcaagta aagaattaac aagacttata aagtctaaag aagaaataga
    58261 atggttatta aatagggatt acaaaataga cccagtcgtt acttttgttg gtgatagata
    58321 tcagttttct ataagacaaa gagatgcatt aaaaagggca gtctgtactg atgaaaaaaa
    58381 tattataaga caatcaaaaa ggctttctct agataaaatc aaagaagata ccgtaaatat
    58441 agatggcttt aatttgataa tatccataga ggtagcatta tctggtggta ctctagtaat
    58501 aggaagtgat ggcaatataa gagatttagc aggtcttagg ggaacctata agattataga
    58561 taaaacagaa gaagctttga atctgatagg taaatttttt aataaataca atgcacagaa
    58621 tcttaaattt tatttagatg ctccagtttc taattcagga aatttaaagt ataggatatt
    58681 agagcatgcc aaaacttggg gaattgaaac tgaagtagaa ttagtaaaaa atgcagatgt
    58741 tgtattggaa aaattagata gagtagttag tagtgatgca gtcatagttg acaagtgtat
    58801 aagttatttt aatgtggcta gaggtataat tgaagagtat attaaagaat gtaatatcat
    58861 aaatttaaat aaatagataa atataggtga gaatatataa gtatatgtag caatattctt
    58921 agtaatacaa gtaaagtttg aaaataggag aacgaataca tatcgaattt cataaaatgt
    58981 tgtaaaaaga catatgagag gatggatatg tgtgaaatta actaaactaa atattaaaaa
    59041 atatagagca cctatatata aatatgcttt agcaaatgta aatttgaggt ctgctaaatc
    59101 tactaattca agtatcataa cagtaatacc tcagggagcc aaaatggaag tattggatga
    59161 agaagatgac tggattaagg tgatgtacaa ttctcaagaa ggatatgtgt ataaggattt
    59221 ggtatcagta agcgaatatg cttggagtaa cttaaactta agagaagata aatctacaac
    59281 ttccaatata attacagtaa ttcctgaaaa atctagggtt gaagtccttc aagtagatgg
    59341 agattggagt aaggttgtat atgatgataa aataggatat gtttttaatt attttttatc
    59401 aattgatggg aataaaccaa atgaattaga ttataagtat ttttatactg acatgattaa
    59461 atttgttaac gaaaataaca ttaaaagtac tagcgattat ctaattgtaa cagaccttag
    59521 aaataaatat acttatattt ttaagaaaga taatggagga tggggacaac tttacaagtg
    59581 gcaatgtact ataggcaagc ctgagactcc aactataaca ggtatatttt atataagtgg
    59641 aagaaaacct tcttttggaa cggatgagta ttcagttaag tatgctacta gaattaaagg
    59701 tggatattac tatcattctg tactatatga ttcaacagga agttatataa tagatggcag
    59761 acttggtgaa gctcttagtc atggatgtat aagattaagt acggaaaatg caaagtggat
    59821 atatgataat ataccagata caacaacagt tataattcat taagaaaaat tttgagtttt
    59881 ttattgggat aataattctt aaattaatag aattatatat taacttctca taaagagtac
    59941 tatttaaaaa gtgtaataag agagtgctat taacaaaaca aagatatttt gaggcactct
    60001 cttataaata tacataatta agatattttc ataaacaatt ctataatctt atctttatca
    60061 aagaaaacag gattagcacc agcacaagca tctttcatag agttttctgc aagcaattca
    60121 aaattaggat tatcaacacc tacatctttt aaagattttg ggattccaac ctcttcagaa
    60181 agagctttta tcttatctat tacaaagtca acacactctt tatctgattt attatttaca
    60241 tccattccaa taacttcagc tattggtcgg aatttggcag gggctgattt agcattttcc
    60301 tcctcaacta ttggaagtag catggcatta catactccat gaggtaaatc atataaacct
    60361 cctaattgat gagccatagc atgtacattt ccaagacctg cattactaaa ggcaattcca
    60421 tttaaaaaac aagcataaca catttgttct ctagcttcta tgtcattacc atttttaaca
    60481 gctcttggaa ggtatttaaa tatctgcttt atagcatata aggcagttga atctgtaaca
    60541 tcataagcac cattagctac tacagcttct atagcatgag ttagtgcatc cataccagtt
    60601 gctgctgtta aattagatgg tttgctaatc attaattctg ggtcatttac tgtcattgtg
    60661 gctagtgaat tggtatcaac cattatcatc tttacatgtc tgtcttcatc agttataaca
    60721 tagtttattg taacttcagc agatgtacca gcagtagtag ttatagctat gataggaaga
    60781 cattttttag aagttttgtt gataccttca tagtctctaa tatctcctcc attagtggct
    60841 aatatagaga tagctttacc acagtcttgt ggagaaccac ctcctatagt tataacgaag
    60901 tcgcaatttt ctgattttaa tattttaagt cctttattca cattagttac agttggattt
    60961 tgtttaactt catcataaac aacaaagtct acatctatct gagataaaat atctgttact
    61021 ttttttacag taccatttga aactagaaat ttatcactaa caataaatgc ttttttagtt
    61081 cctaatgatt taattgaatc tttagcttca ttaagacatc ctttcccaag taaatttatt
    61141 ggtggtacat aataaatgct cataactaaa atctcctttt attttcattg atttttatgt
    61201 aaaaatatat atctaacaat tttcactaac ttactcataa tatatcgtat cttagattga
    61261 gataggattg ttggttctta tataagaact taattcgtaa ttacgattat gattagaatt
    61321 taacatagta tttttatcat gtcaataaaa atataaaaaa tattataaaa aaaacaaagt
    61381 tactgtagtt aaatcagcaa ctttgttttt atagtataaa tcaaataaat acattagttt
    61441 aaaacaaaat ttttaattat tatgttttga tatcttccat atacagaata ttaatctaat
    61501 ttattacaat gtcttcatta cgttcttcca tcattgattg aatatttttc tgagcattta
    61561 agagtaattt ttttatcagt tctatttttt cgtcattagc tctaaataaa ggcagtgtta
    61621 cactaacagc agctcttata catccatttt ttcttattgg tacggcaaga cattttaggt
    61681 gttccattga ttcctcacac tctgaagcta tttgtgttct ttgaacttca agaagctggt
    61741 cgtataaaac atcaaaatct gtaattgatt tttctgtaaa accttttaga ccatctggat
    61801 ataagcttat tagtttttcc ttgtcaaaat cacataaaag agcttttcca agacctgtac
    61861 aattagcagg tatttttttt ccaacataag aaataagtct aattggttct ggagaatcta
    61921 cttttccaat ataaagaact tcattattgt caagtatacc aagctgacaa gtttcagaac
    61981 aggaattaac tatattagtc atttcgtcaa ttatatagtt aaaaatagtt cttttttcaa
    62041 aaaatgaaga ccctaatgtg taagaacgta tccctataga atatttggat gtgtttttat
    62101 caatagtaat gtattttcta gcattaagtg tatgaactat aggaaagatg ctactttttg
    62161 gagcattgat aacatctgct atttctgtaa gagtatatcc attttcggat tctgctaatg
    62221 cttctaaaat atctaatatc ctagctgttg ggcgatgatt atctgaagtc ataaatttcc
    62281 ccctcttttt attaatttaa agtattagaa tatgttgatt ttagcacact atacgatatt
    62341 ttacaatgta gaaaataaat atgtaaattt atatataaat aagctcttga tttagataca
    62401 gatagatatt tttttagact gtacattaag gaataactaa tttccaaaat gtacctaaag
    62461 aaagtaagtg atatttagtt atataattta agtaaatata tgcaatagtt atttttatat
    62521 gtaaatatca aaatattatg aacttatatt ttatctattt tttacactgt ataaaaactt
    62581 tatagttttg aatactatat aattttaaat acgctgtatt tttgcatata aggaagtcat
    62641 ttgataatat acaaggtatt atcagaaagt ttgaaaaaat tttgacaaaa atttattttt
    62701 tttattgact cataaatagg aaaatgctat cattaattca aagattcgta attaaaaact
    62761 tagttcttaa atacgaaccg aaacggccgt tagaattaaa gctaaaaact taataagagt
    62821 aattaaatat catgttttag gaggattaac tttatgataa tggattttat taaaaaaatt
    62881 cctgcaggta tgatgatagt gccaatgttt atagcagctt tcattaatac cttttgccca
    62941 gatattgtac aaataggttc gtttacgaca gcagtatttt caagtgttgg gtctgcaact
    63001 ataattgggg ttcaactggt atgcttggga actcagcttc aatttagaga aatgccaaaa
    63061 gttttaaaga gaggtggtat acttcttggt tctaaatttg ctataggtgc tttgataggt
    63121 atacttatag gaaagctatt tggaatggat ggtgtccttg gtcttacaac attggctgtt
    63181 ataagtgcag ttacaaatag taatggtagt atatatcttt cattgatgac ttcatatgga
    63241 gatgaaacag attgtgcaac tatgagttta cttactttaa atgatggacc attttttaca
    63301 ttaatagctc ttgggacttc aggtcttgca aatgtaccat tgttgtcatt attggctgca
    63361 atagtgccaa tacttgttgg tatgataata ggaaattttg acaaaaaaat gaaagagttt
    63421 ttagagccag ggtgtaattt actcgtacct tttgtagggt ttgcacttgg tagtagcata
    63481 aatcttgcaa gtatactaaa aggaggttta tcaggagtat tacttggatt aatatctgta
    63541 tttgtaggag gtatatttat agtattctgt gataaattta taggaaaacg tccaggatat
    63601 gcaggatggg ctgtagctac aactgctgga aatgcaattg ctgtacctgc tgctgttgca
    63661 ttagttgacc catcatggca accatatgtt gcaacagcta caacacaagt ggcagccgca
    63721 gtagttgtca ctgcaatatt agtacctctt ataactagtt ggtgggctaa gaagtatgga
    63781 tgtcctaagt tcccaaaaca aaatgaggat ggtacaataa cagcttaatt tatattacag
    63841 tgagttgttg gtaaaataat aaattcttta attagatttt aggatattaa taaaattata
    63901 ttatttataa aggagagcaa gaataatgat aaatgcagtg ataattgatg aaaaagataa
    63961 tgttgcagta gctattgaag caatagctaa aggtagtgaa attagtttta aattaaaaga
    64021 caaaacagta aaaacgatta cagcactaga tgatataact atttatcata aattggctat
    64081 aaaagatatg gcccaaggtg ataaagttac taaatatggt gaacatatag gagaagcaaa
    64141 tcaggagata aaaagtggtc aacatgtaca tattcataat gttagaagtg ttagagagga
    64201 tttggataaa caagttatga ctaatatata aaataatatt tatagagtta taaaagttgt
    64261 attcattgat tttagtgtca aatagttttt aaataggttt ttagctgttt gattagtgag
    64321 tgtaataaaa attataatat ataaaaatta tagaaagtat atagactatt ttaggaggaa
    64381 atcagtatga aattttatgg atataaaaga ccagatggaa gagttggtat aagaaaccac
    64441 atattaatat tgcctacgag tgtgtgtgca tcagatacaa ctagaataat agcatcacaa
    64501 gttcaagggg cagttacctt taataatcag aatggatgtt cacaagtaca ttcagaccaa
    64561 caattaacta tggatgttat ggctggttat gcagcaaatc caaatgtata tggtgtaata
    64621 gttgtatctt tgggatgcga aaattgccaa aatgatttgg tagttgatgc aataaaagag
    64681 agaacaaata agccaataaa aactcttgta atacaagaag aacatggaac tttaaaaact
    64741 atagaaaaag ctgttcgtta tgctagagaa atggcacaag aagcttcttt gcttagaaaa
    64801 gaagaatttc caatatctga acttatacta ggaactgaat gtggtgggtc tgacccaaca
    64861 agtggattag cagcaaatcc attaataggt gaattaagtg ataaacttgt cgatttagga
    64921 gcaacatcaa ttttaagtga aactactgaa tttataggtg cagagcatat actagctagg
    64981 agagcagtaa atgaagaagt aaaagaaaaa atattacata tagtacatag atatgaaaat
    65041 tcattaaaat tggttggaga agaagttaga gaaggtaatc catctcctgg aaatatagct
    65101 ggtggtttaa caagtttaga agaaaaatca cttggttgta tacataaagg tggtcataga
    65161 caaataagtg aagtatatga ttatgccaaa caaattgata agaaaggtct tgttataatg
    65221 gatacccctg gaaatgatgc ttcatctgtt gctggtatgg tagcaggagg agcacaaata
    65281 gtggtattta gtacaggaag aggaacacca tcaggaaatc caatagcacc agtaataaaa
    65341 ataactggaa ataaaataac ttttgcaaat atggaagata atctggattt tgatgctagt
    65401 ccagttatat atggtccaca aacaatggaa gaattaacag atgatttgtt aaatatggtt
    65461 gtagatgtag caaatggaaa acaatcaaaa gcagagtccc ttggatatac tgaaatggca
    65521 atagctagag tatgcaacta tgtataatct ttaagtaaga aaataaatac atagaatttt
    65581 aataaagggt gagattatga agtttgtaag ttttactgaa ggagaaaatg aatgtaaaag
    65641 aactggagtt ttttctaaag atgaattatt tattatagat gttaactctt taaatctcag
    65701 tagaaatttt aaggatttaa atgaattaat tcaaaatgta tctagtgaag atattattaa
    65761 gttgaaaact attataaatg aaagtacatt ctataattat gatgttttta aaagagagag
    65821 atgtactgta catgttccta tagaaaaacc aatacatgat atcttatgtg tgggagtgaa
    65881 ctataaagac catcttgaag aaactcaaac tcactttgat gatagttttg aagaaccaca
    65941 aaaaacggtt tattttacaa aacgtgtgac aaaggcaata ggtccagaag atgagataga
    66001 tggtcatttt gagataaata atcaactaga ctatgaagtt gaacttggag tagtaatagg
    66061 taaaacaggt gttaatatta gaaaagaaga ggtagaagat tatatctttg gttacactgt
    66121 tataaatgat atttctgcta gaaagttgca aaaagaacat gttcaatggt ttagaggaaa
    66181 aggattagat acatttacct ctttaggtcc atgtatttta cataaaagtg cagttccttt
    66241 tcccataaaa cttaaagtat gtagtagggt aaatggtgaa gaaagacaaa gttctaatac
    66301 agggttattc atatcagacg tttcagacat agtttcagaa ctttcaaaag gtatgacttt
    66361 agaggctgga gacattatag ctactggaac accttctgga gtagggatgg gattttcacc
    66421 tcctcgatat atgagtagtg gagatgtagt tgaatgtgag attgagagta ttggaatttt
    66481 aaaaaattac attaagtaac tgttttaata taattaatat taaagctaaa tctgatgtat
    66541 taatgaacat attaaaataa attttaggag tttaaattat gaaagcagaa tttttgacac
    66601 cagttgttac aatatttgat gaagaaggaa atttagataa agaaggtaat aaaaaagtgt
    66661 atgaccatct tatagatgga ggtgtagatg gactagtcat aatgggaagt actggagagt
    66721 tctttaatat gtctatggat atgcaaaaag aacttataga tttagtaact agtcatgtaa
    66781 ataagagagt aaaagtgttt ataggtacaa gtcgtatgtg tataaatgaa tctatagaac
    66841 tttcaaacta tgcacataat agtggagcag atggtgttat gataataagc ccttattatt
    66901 tctctcttga tgatgatagt attgagttat tttatagtga aatagctaag aatacagagg
    66961 ctgaaatata tttgtacaat tatccagata gaactggtta tgatttaagt ccagaactta
    67021 cattaagact tgcaagaaaa cataaaaaca tagttggata taaggataca gtaactttga
    67081 tgggacatac cagagattta ataaatacta tgaaaataga gttcccagaa tttaaggttt
    67141 atagtggtta tgatgaaaac tttatacata atctaatgtc tgggggagca ggttgtatag
    67201 gggggttatc aaatttaatt ccagaagttt gctccaaatg ggctgaagct tacaataata
    67261 gagatatgga gaaggttata gaaattcaaa aatatattaa taaagcaatg gatttttact
    67321 taataaccaa tccatttata ccagcaatga aaaaagctat gaatatcaga gggttacaaa
    67381 taagtgatta tatgactgct ccatttgtaa aaccaaatga aaaacaagta tgtgaaatta
    67441 aaaaattgat gaatgaatta aatatatgtt aaatcaacct tgcaaagagg tcaacaataa
    67501 attacaatta tcttaataaa aattaaatta aaataatact agggtactat attagtttaa
    67561 tagggaaagt gatgaaaatt cactacagcc cccgctactg tatacggata cgaaatcaaa
    67621 atccactgaa atttataaaa attttgggaa gggtgatgga ggaaaagccg tgagtcagga
    67681 gacctgccca gtattatata agttcaattt agggtggaga ttgtaattta taataaaatg
    67741 aagtatcaat tcgtttttgt aaagttgata tatgaacttc tccttattaa attaggagaa
    67801 gttttttatt ttattaaaag gttatactta ttaaagatga ctttaggata actttaataa
    67861 gtatacttta aaaagcatat attattaaag ttttttagcc actcataaaa aataagatat
    67921 tggagtgaaa gagatgaaat ttaaatcaaa tgttttaaag cagttttttt taattgctat
    67981 ggtaattttt atggtaggag gtcttatagg gtgtagtaaa agtgacaaag agaataaaca
    68041 agctagtact ggtaagaaat tagaattaaa atatgctagt ggatttagtg ttgaagattt
    68101 agaagatgga attaaaaaag taactgatgg agataatcga gaactgattt taatcccaaa
    68161 gaagattaaa attcctgaaa aatataaaaa tgctaatata gttagaacgc ctgtggacaa
    68221 tgtattaata gcatctacaa cacaggcttg ttctctaaga acaatagatg aactagatag
    68281 tataaaagcc gtaacaacac aagagcagta ctggactatt aaagaaatta aagatttaat
    68341 gaaagatgga aaaatacatt acgttggttc aaatttagca ccagattatg aaaaaatagt
    68401 agacttaaat cctgacttaa ctatagtgag tagtggttta tcagaggctg atacaaaatt
    68461 tattgacaaa ttaaaagaat tagggcttaa ttatgttgta gacaatgagt ataaagagca
    68521 aaatccattt ggaagaatgg agtggacaag tttaatagct gcattttatg ataaagaaga
    68581 tatggctact agtgaactaa ataaaactgt acaaaaggta gaagaagtaa gtaaaaaaat
    68641 aaaaaacaaa gctaaaccta aagttgtatg ggcatctgta tatgaaggaa gtgcttatat
    68701 agctcctaaa gattcatatg tggataatat gataaaaatg gctggtggaa taaatgcatg
    68761 tgcttcaata gattcaaatg aagggcgagt aagtattgaa caattgcatg aagttgcaaa
    68821 agatgcagat atatttgtat actcatcaag ttcagattat gcaccaaatt tagattctat
    68881 aaaatctagt gcacctgtat tggctgattt ggatgttgta aaaaacggga acctatgggt
    68941 gtttgctcca gattattatc aatcagtaga taagacagac gaattaatag tagatttagt
    69001 tgagatgttc cacccaggta ctacaggtga aaaaatcaaa cattatataa attatgataa
    69061 atagtacaga gaggacacaa aaagataggt tttatagatt ttagttaata tagctttgct
    69121 aaaaggagta tacaaatgga ttttatcaat aaaatgagaa taaggaatac gacaatattt
    69181 atagtattaa ttataagtat gatacttact tttttagtgt gtgtagcatt tggctctgta
    69241 aaaattgaat ttaaagaagt aatagatgtt gtattaagag gtatggataa tacagaacat
    69301 tataaaataa tatacaatat aagaatccct agagtacttg caaccatggt aggtggagca
    69361 tgcctagcag tatcaggtat tttattacag atatttttta aaaacccaat agttgaaccg
    69421 tatatattag gagtatcttc aggttctact ttatcagtag ctctcatgat tttgggagga
    69481 tacacattgg gatttgagag tgtaaattca atgagtatat ttgtagcagc ttttatagga
    69541 gctttaattg taatgtctat agtcatttta tttgcaaata aggtaaagaa tataacaact
    69601 cttttaataa taggaattat gaccggatat gtatgtagtg gtataacaaa tgtgttacaa
    69661 tcatttgcaa atagtgataa attaaaagaa tttactatgt ggtctatggg aagtttttct
    69721 ggatttacat gggaaaaggt agaaatactt ataatagttg gtatattagg tcttttgatg
    69781 actgtattca taataaaacc tttaaatgct tttttactag gagaagagta tgcaaaaagt
    69841 attggcataa atataagatt ttttagagtt ttgatagtat ttatatctag tatattagca
    69901 gcaatagtat cagcatttgc aggacctata gggtttattg gacttgcagt gccacaaatt
    69961 tcaaaaatga tatttaaaac atcagataat agagttttga taccagtagt aatattttta
    70021 ggcagtatag ttacagctct ttgtgattta atatcaagag taattttatc accagtagaa
    70081 ttaccaataa gtacaataac atctttatta ggagctccaa ttgtagtaat gttattggtg
    70141 aaaaggaagg atagggctta gacatgttga aaactaataa tttaagtgta ggatacaata
    70201 acaaagttgt tataagtaat ataaatgtag aagtaaaaaa tggagaaata ctatgtcttt
    70261 tgggaagtaa tggagctgga aaaactaccc tattaaggtc cttatctaaa cttatatcac
    70321 caataaaagg tgaaatatat ttgaatggtg taaacataaa ttgtatatca agaaaagcat
    70381 tatcaaaaaa aatggcttta gtacttacaa atagattatt aggtgattta atgactgtac
    70441 aagatatagt caatatagga aggtatccat atacaggatt ttttgggagt ctatctaaga
    70501 aagatttaat aatggtagat gaagcattgg agtctgtaga tgccttacat ttaaagaaaa
    70561 gatattttga tgaactaagt gatggagaaa aacaaaaggt gttggttgca agggctcttg
    70621 ttcaagaacc agaaataatt atattagatg agcctacaac tcacttggat ataaaacata
    70681 gattggaact cataaacata ctgaaaaaat taagtaaaga aaagtcaata tcagtaatac
    70741 tttcattgca tgaaatagac atagcattaa aaagttgtga taaagttgct cttataaaaa
    70801 ataataaagt catagcttat ggccagcctg aagatgtagt agatgaggat attataaatt
    70861 cgctttatga attggatgat aaaaacttta atagtctttt aggttcagta gaaattagta
    70921 ataaatctaa aaatgaagtt tttataattg gtggtggggg taaagcaaca ccaatttata
    70981 gagcttttac taaaaaaggt ataggtctgt attctggaat aatacatgaa aatgatattg
    71041 attatgaaat tggtagaact atggggataa agatgtttac agaaaatcca tttgagccta
    71101 taagtgatga gagtttcgat ttggctatta gaaatttaaa tgattccaag attataatag
    71161 atacaggatt tagtgtagga gagacaaata agaggaatat agatattata aaagaagctt
    71221 taaaattgga taaaaaagtt tattctttta gaaatagaga tgagagtaag aagtattatg
    71281 acagtttgga tagtaagata gaacatatag ataaagtttc tcaaataatc aatagtgcag
    71341 atataaataa tttattataa tttatgaaat aaaatgtact tatgtgttat agaaaaaaga
    71401 gtatagatta taattttttt gaaattacaa tctatactct tttgttattt tgtttatgta
    71461 tttatatatt tataaaactt tagcatttta tagataacca atagcttcct ctctagttaa
    71521 aaaaaagtga atccctgtag tcgattcttt ccatctattt tcattaaaat cttcagctac
    71581 aatcgtttct cctactctat atataaaatt ttcatcagca tatgcacgag cacttttaaa
    71641 agattcttta ccatctacac tagtaattga cagtactttt gccttatcac atctacaagc
    71701 atttgatgta gcagacactc tttttgcgtc gctgggtatt aataattgta ccattctaaa
    71761 attaaaacat tttttatagc ctataaatgc tcctgtttca ggacaataca atttaaaaaa
    71821 acgagtactt tcatctgata ttactccatt taaagtagca tattctaaat tggaattttc
    71881 taaattagct cctctaatat ctgagttaga taagtcacaa aatctaaaac ttgcaccact
    71941 taagtctgca ttttttaata tagaattttt taatgaacaa tccgaaagat aagaattatt
    72001 aaaaatagag ttttctaaat ctgctttttc taaatttaaa ttgataaggt cagaccacga
    72061 aaagtcaata ttacttaagc agtatcctct taagtccata ttttctaatc ttaattcttt
    72121 taaatctgcc ttttctccag cattattgtt tttaagccat aaataatgtt tctcaagtgt
    72181 tttttctaat tcttgtttag aaatagtttt cattaaaatc accttcataa atttattttt
    72241 atatatgtag tagcaaaata gtcatatatt taattatata acaataaata aaaaacttct
    72301 a
//
LOCUS       DAYAKB010000013        72084 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.013, whole genome shotgun sequence.
ACCESSION   DAYAKB010000013 DAYAKB010000000
VERSION     DAYAKB010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72084
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.013"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            84..2273
                     /locus_tag="ACGI3L_001017"
     CDS             84..2273
                     /locus_tag="ACGI3L_001017"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HFG9196744.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYGISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKKFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEGDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2341..3108
                     /locus_tag="ACGI3L_001018"
     CDS             2341..3108
                     /locus_tag="ACGI3L_001018"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFG9196745.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3166..4182
                     /locus_tag="ACGI3L_001019"
     CDS             3166..4182
                     /locus_tag="ACGI3L_001019"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFG9196746.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCVNSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4248..4496
                     /locus_tag="ACGI3L_001020"
     CDS             4248..4496
                     /locus_tag="ACGI3L_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196747.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4672..5169)
                     /locus_tag="ACGI3L_001021"
     CDS             complement(4672..5169)
                     /locus_tag="ACGI3L_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HFG9196748.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5413..6477)
                     /locus_tag="ACGI3L_001022"
     CDS             complement(5413..6477)
                     /locus_tag="ACGI3L_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9196749.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6480..7577)
                     /locus_tag="ACGI3L_001023"
     CDS             complement(6480..7577)
                     /locus_tag="ACGI3L_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9196750.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7591..8526)
                     /locus_tag="ACGI3L_001024"
     CDS             complement(7591..8526)
                     /locus_tag="ACGI3L_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9196751.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGN
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8655..9302)
                     /locus_tag="ACGI3L_001025"
     CDS             complement(8655..9302)
                     /locus_tag="ACGI3L_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9196752.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTIKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9295..10458)
                     /locus_tag="ACGI3L_001026"
     CDS             complement(9295..10458)
                     /locus_tag="ACGI3L_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9196753.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSMHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10642..10986
                     /locus_tag="ACGI3L_001027"
     CDS             10642..10986
                     /locus_tag="ACGI3L_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HFG9196754.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11017..12618
                     /locus_tag="ACGI3L_001028"
     CDS             11017..12618
                     /locus_tag="ACGI3L_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HFG9196755.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFSKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12637..13737
                     /gene="dprA"
                     /locus_tag="ACGI3L_001029"
     CDS             12637..13737
                     /gene="dprA"
                     /locus_tag="ACGI3L_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFG9196756.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13770..15857
                     /gene="topA"
                     /locus_tag="ACGI3L_001030"
     CDS             13770..15857
                     /gene="topA"
                     /locus_tag="ACGI3L_001030"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFG9196757.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNIGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16022..16807
                     /gene="codY"
                     /locus_tag="ACGI3L_001031"
     CDS             16022..16807
                     /gene="codY"
                     /locus_tag="ACGI3L_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFG9196758.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            16914..18179
                     /locus_tag="ACGI3L_001032"
     CDS             16914..18179
                     /locus_tag="ACGI3L_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFG9196759.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18210..18980
                     /locus_tag="ACGI3L_001033"
     CDS             18210..18980
                     /locus_tag="ACGI3L_001033"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9196760.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19089..19535
                     /locus_tag="ACGI3L_001034"
     CDS             19089..19535
                     /locus_tag="ACGI3L_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFG9196761.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19553..20746
                     /gene="nifS"
                     /locus_tag="ACGI3L_001035"
     CDS             19553..20746
                     /gene="nifS"
                     /locus_tag="ACGI3L_001035"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HFG9196762.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            20800..21240
                     /gene="nifU"
                     /locus_tag="ACGI3L_001036"
     CDS             20800..21240
                     /gene="nifU"
                     /locus_tag="ACGI3L_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HFG9196763.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21529..22608
                     /gene="mnmA"
                     /locus_tag="ACGI3L_001037"
     CDS             21529..22608
                     /gene="mnmA"
                     /locus_tag="ACGI3L_001037"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFG9196764.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22751..22989
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23057..25696
                     /gene="alaS"
                     /locus_tag="ACGI3L_001038"
     CDS             23057..25696
                     /gene="alaS"
                     /locus_tag="ACGI3L_001038"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFG9196765.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25721..25978
                     /locus_tag="ACGI3L_001039"
     CDS             25721..25978
                     /locus_tag="ACGI3L_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFG9196766.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            25988..28159
                     /locus_tag="ACGI3L_001040"
     CDS             25988..28159
                     /locus_tag="ACGI3L_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196767.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDIMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28365..28790
                     /gene="ruvX"
                     /locus_tag="ACGI3L_001041"
     CDS             28365..28790
                     /gene="ruvX"
                     /locus_tag="ACGI3L_001041"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFG9196768.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            28868..29155
                     /locus_tag="ACGI3L_001042"
     CDS             28868..29155
                     /locus_tag="ACGI3L_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFG9196769.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29437..29895
                     /locus_tag="ACGI3L_001043"
     CDS             29437..29895
                     /locus_tag="ACGI3L_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFG9196770.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30012..30749)
                     /locus_tag="ACGI3L_001044"
     CDS             complement(30012..30749)
                     /locus_tag="ACGI3L_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFG9196771.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            30966..32642
                     /locus_tag="ACGI3L_001045"
     CDS             30966..32642
                     /locus_tag="ACGI3L_001045"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFG9196772.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            32848..33048
                     /locus_tag="ACGI3L_001046"
     CDS             32848..33048
                     /locus_tag="ACGI3L_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1290 family small acid-soluble spore protein"
                     /protein_id="HFG9196773.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33102..34265
                     /locus_tag="ACGI3L_001047"
     CDS             33102..34265
                     /locus_tag="ACGI3L_001047"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9196774.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34476..34898)
                     /locus_tag="ACGI3L_001048"
     CDS             complement(34476..34898)
                     /locus_tag="ACGI3L_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HFG9196775.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(34919..35755)
                     /locus_tag="ACGI3L_001049"
     CDS             complement(34919..35755)
                     /locus_tag="ACGI3L_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFG9196776.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36053..36649
                     /locus_tag="ACGI3L_001050"
     CDS             36053..36649
                     /locus_tag="ACGI3L_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HFG9196777.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            36679..37398
                     /locus_tag="ACGI3L_001051"
     CDS             36679..37398
                     /locus_tag="ACGI3L_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFG9196778.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37400..37939
                     /gene="scpB"
                     /locus_tag="ACGI3L_001052"
     CDS             37400..37939
                     /gene="scpB"
                     /locus_tag="ACGI3L_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFG9196779.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38101..38730
                     /locus_tag="ACGI3L_001053"
     CDS             38101..38730
                     /locus_tag="ACGI3L_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HFG9196780.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38684..39112
                     /gene="ytfJ"
                     /locus_tag="ACGI3L_001054"
     CDS             38684..39112
                     /gene="ytfJ"
                     /locus_tag="ACGI3L_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HFG9196781.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39360..39800
                     /locus_tag="ACGI3L_001055"
     CDS             39360..39800
                     /locus_tag="ACGI3L_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9196782.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDINNKDKLFTSLEESKNIIEQLF"
     gene            39816..41267
                     /locus_tag="ACGI3L_001056"
     CDS             39816..41267
                     /locus_tag="ACGI3L_001056"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HFG9196783.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALILLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41358..42026)
                     /locus_tag="ACGI3L_001057"
     CDS             complement(41358..42026)
                     /locus_tag="ACGI3L_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HFG9196784.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            42295..42435
                     /locus_tag="ACGI3L_001058"
     CDS             42295..42435
                     /locus_tag="ACGI3L_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196785.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(42610..42930)
                     /locus_tag="ACGI3L_001059"
     CDS             complement(42610..42930)
                     /locus_tag="ACGI3L_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFG9196786.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(43050..43787)
                     /locus_tag="ACGI3L_001060"
     CDS             complement(43050..43787)
                     /locus_tag="ACGI3L_001060"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFG9196787.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            44002..45825
                     /gene="acd"
                     /locus_tag="ACGI3L_001061"
     CDS             44002..45825
                     /gene="acd"
                     /locus_tag="ACGI3L_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HFG9196788.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISEGNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            46040..50338
                     /locus_tag="ACGI3L_001062"
     CDS             46040..50338
                     /locus_tag="ACGI3L_001062"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFG9196789.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            50542..51003
                     /gene="rimP"
                     /locus_tag="ACGI3L_001063"
     CDS             50542..51003
                     /gene="rimP"
                     /locus_tag="ACGI3L_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000028 - ribosomal small subunit assembly
                     [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFG9196790.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            51033..52187
                     /gene="nusA"
                     /locus_tag="ACGI3L_001064"
     CDS             51033..52187
                     /gene="nusA"
                     /locus_tag="ACGI3L_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFG9196791.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            52194..52475
                     /locus_tag="ACGI3L_001065"
     CDS             52194..52475
                     /locus_tag="ACGI3L_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFG9196792.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            52465..52776
                     /locus_tag="ACGI3L_001066"
     CDS             52465..52776
                     /locus_tag="ACGI3L_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L7Ae/L30e/S12e/Gadd45 family ribosomal protein"
                     /protein_id="HFG9196793.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            52798..54738
                     /gene="infB"
                     /locus_tag="ACGI3L_001067"
     CDS             52798..54738
                     /gene="infB"
                     /locus_tag="ACGI3L_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFG9196794.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            54781..55161
                     /gene="rbfA"
                     /locus_tag="ACGI3L_001068"
     CDS             54781..55161
                     /gene="rbfA"
                     /locus_tag="ACGI3L_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFG9196795.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            55142..56125
                     /locus_tag="ACGI3L_001069"
     CDS             55142..56125
                     /locus_tag="ACGI3L_001069"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFG9196796.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEDVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            56138..57043
                     /gene="truB"
                     /locus_tag="ACGI3L_001070"
     CDS             56138..57043
                     /gene="truB"
                     /locus_tag="ACGI3L_001070"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFG9196797.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            57174..58103
                     /locus_tag="ACGI3L_001071"
     CDS             57174..58103
                     /locus_tag="ACGI3L_001071"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFG9196798.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            58207..58464
                     /gene="rpsO"
                     /locus_tag="ACGI3L_001072"
     CDS             58207..58464
                     /gene="rpsO"
                     /locus_tag="ACGI3L_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFG9196799.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            58704..59549
                     /locus_tag="ACGI3L_001073"
     CDS             58704..59549
                     /locus_tag="ACGI3L_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFG9196800.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            59674..61785
                     /gene="pnp"
                     /locus_tag="ACGI3L_001074"
     CDS             59674..61785
                     /gene="pnp"
                     /locus_tag="ACGI3L_001074"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFG9196801.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            62051..62794
                     /locus_tag="ACGI3L_001075"
     CDS             62051..62794
                     /locus_tag="ACGI3L_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9196802.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKAGKLSDVFK"
     gene            62952..64199
                     /locus_tag="ACGI3L_001076"
     CDS             62952..64199
                     /locus_tag="ACGI3L_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFG9196803.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINSVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            64234..64479
                     /locus_tag="ACGI3L_001077"
     CDS             64234..64479
                     /locus_tag="ACGI3L_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HFG9196804.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            64489..65712
                     /gene="dapG"
                     /locus_tag="ACGI3L_001078"
     CDS             64489..65712
                     /gene="dapG"
                     /locus_tag="ACGI3L_001078"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFG9196805.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            65825..66559
                     /locus_tag="ACGI3L_001079"
     CDS             65825..66559
                     /locus_tag="ACGI3L_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HFG9196806.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            66682..69093
                     /locus_tag="ACGI3L_001080"
     CDS             66682..69093
                     /locus_tag="ACGI3L_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFG9196807.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            69096..70154
                     /gene="mnmH"
                     /locus_tag="ACGI3L_001081"
     CDS             69096..70154
                     /gene="mnmH"
                     /locus_tag="ACGI3L_001081"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HFG9196808.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNDVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            70148..71482
                     /gene="rimO"
                     /locus_tag="ACGI3L_001082"
     CDS             70148..71482
                     /gene="rimO"
                     /locus_tag="ACGI3L_001082"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HFG9196809.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHKIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            71469..72011
                     /gene="pgsA"
                     /locus_tag="ACGI3L_001083"
     CDS             71469..72011
                     /gene="pgsA"
                     /locus_tag="ACGI3L_001083"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFG9196810.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
BASE COUNT        28989 a         7643 c        12959 g        22493 t
ORIGIN      
        1 aatatacaaa tatataaaaa gtttgtttag agttatagtt aatgtgtgta ttaatttaat
       61 actaatttat tggaggttta aaaatgaaat acataataaa aagagatggt acaaaagaac
      121 tttttagtaa aagtaagatt gaagatgctg tctataaagc tagtataaat agtgaaggtg
      181 gagtagatag agagttggca tatggtatat caagaaaaat agctaatgac tataattcta
      241 tggaaaaatg cttatccgta gaagaaatac aagatatagt tgaagtacta cttatggaat
      301 caaatagaaa agatatagca aaacactaca tattatatag agaaagacgc tctgaaataa
      361 ggactaaagc ttgggagttt gatgaattac aaaaatcaat atggaagaac aagtatagac
      421 ataatggtga gagttttgat gaatggataa agagaatttc aaataatagt tcaagaatat
      481 caaaactaat aagacaaaaa aaatttctat ttgctggaag aattttagca aatagaggat
      541 tacagaaaga gggaaaaaaa gtaacatatt ctaattgtta tgtaatagaa ccaccaaaag
      601 atagcataga agatatattt gatactgcaa aaaaacttgc tagaactttt agttatggtg
      661 gaggagttgg aattgatatt tcaaagctaa gaccaaaagg agcgaaagtt aacaatgctg
      721 caaaacatac gactggagca gtctctttta tggaacttta cagtatgaca actggcttaa
      781 ttggtcaaag agggagaaga ggagctctta tgatttctat ggatgtaaat catccagaga
      841 tagaagactt tatagatata aaaacagatt tggagaaggt tactaaagca aatatttctg
      901 taagagtaac agatgaattt atgcaagctg taagagaaaa aaagttatat aattgtactt
      961 ttgaagttga aactactgga gaaaaaatag ttaagatagt aaatgcttat gatttattta
     1021 ataaatttgt gaaaaataac tgggattatg cagaaccagg tatattgttt tgggataaaa
     1081 taaaaacata taattttatg agtgaagata agaacttttg cttttcagga gtaaatcctt
     1141 gtgcagaaga accacttcca agtggaggaa gttgtctact tggctcaata aacttgtcag
     1201 agtttataat acaaccattt ggtgaacatg ctacttttga tattaataaa ttaaaatctt
     1261 gcgttagaga agctgtagta gctttaaatg atgtcttaga tgagggattg aacttgcatc
     1321 cattacaaga acaaagagat agtgtacata agtatagaca gataggttta ggtgtaatgg
     1381 gtatagctga tatgcttata aaaatgggaa taagatatgg ttctgatgaa tctttagaac
     1441 tatgtgattt aattggtaag actatgttaa atgaagctgt gaagcaatca gcattaattg
     1501 ctaaagaata tggaacattt agtgagtata aatatgaaaa tatttctaaa tctaagtttt
     1561 ttatagaaaa tctaaatgaa gacactaagg aaatggttaa aaagtatggg cttagaaatt
     1621 cacaactttt aaccatacct cctacaggtt ccatatctac aatgataggt atcagtggtg
     1681 gaatagaacc tatatttaat ctttcatata taagaaaaac tgaaagcttg catgatgagg
     1741 atgtgtatta taaagtatat actccaattg ttaaagagta tatggacaag aaaggtatta
     1801 cagatgaaga atgtttacca gatttttttg ttactgctat gaatatagga tatgaagaaa
     1861 gaataaacat gcaaaaagta tggcaaaagt atattgatgc ttctatatca tctacaataa
     1921 atataccttt tgaaactaca gttgaagatg ttttcaatat atatattaag gcatgggagg
     1981 ctggtcttaa aggagtaaca atatttagag atggatgtaa aaggagtgga attttaataa
     2041 atgaaaaaaa ggaagaaaat aataaagaag ataaaaaaga aaatagtaaa aaagaatatt
     2101 ataaaaataa taaaaaagaa aaagataata aagatgaaaa agccaaagaa ataataaata
     2161 aaaattttga aggagatgaa aaatttgtgt gccctgagtg tggaagtgaa ggaattgcac
     2221 atacaggtgg atgtagtata tgtttaaaat gtggctatag tggatgcaat taaactctaa
     2281 ttaaaaaatt ttaatatatt taaaaattaa atttttaaaa acgaaagatg agggaatggt
     2341 atgcaggata aaagtgtgag ggagattaaa gaaataatag agactttaga agtagaaaaa
     2401 tatatggaat atatagagct gttaagagtt gatgaaagaa aatctgtaca aggtctagct
     2461 ataaaactgg caaaaaagct ggataatatt agaaaagaag aagaaagatt ggaaactata
     2521 aatatatttg agaacgaagg ctatgataaa ggttatttat atattggagg aattgatgag
     2581 gcgggaagag gaccacttgc tggacctgtt gtagcttctg ttgtagtatt taaaaaagat
     2641 accaaaatag aaggtgtaaa tgactctaag aaactgagtg aggcaaaaag agatgaactt
     2701 tttgaagtaa taaaagaaga agcactagat tatggaatag gtatagtaaa caatgaagaa
     2761 atagatgaat ttaatatatt aaatgctaca tatatggcaa tgaaaaaggc tataaattgt
     2821 ttaaaaaaag caccggatta tttattagtt gatgcagcaa caataccagg tattgacata
     2881 tctcaaaatc caattgtgaa aggagattca aaatctatat caatagcagc agcaagtata
     2941 cttgctaaag ttactaggga tagtataatg taccaatatg atagagtata cccagaatat
     3001 gggtttaaat ctcacaaagg atatggaact aaagaacact atgaagctat tgaaaaatat
     3061 ggcataactc ctatccacag aaaaagtttt ttgaaaaata tactgtaaat ataatatgat
     3121 ataatgtata taatataaat tactatagtt aatgggggat taaagatgga atataatgaa
     3181 ttattaaaaa gtgctagaga aaatttaaat ggaagttgta aagtttgtaa ggtttgtaat
     3241 ggggttgctt gtgcaggtga agtgcctggc atgggaggta aaggaagtgg ttcttctttt
     3301 atagaaaata gcaagagttt agaaaaagta aaagtaaata tgagagtaat acatgatgta
     3361 tcaaatcctg atacatctat agagatgttt ggaaagaaaa tgagtgcacc tatatttgca
     3421 gctccagtaa caggaactac tttaaatatg ggtggaaaaa ttaatgaaag agattacata
     3481 gaaccagtag ttgcaggatg tgttaatagt ggtatttatg caatggttgg tgatacggca
     3541 gtagatgctt ttttaatgga aaatttagat gtagtcaaaa agtataatgg agctggaatt
     3601 gtatttatta aaccttggga taatgaaaat attataaaaa agataagatt agctgaagaa
     3661 gctggtgcat ttgcagttgg agttgatata gatgcctgtg gtctagtaac tttatcatta
     3721 catggaaaac cagtacttcc taaaaatgtt aaacaaataa aggagttagt aaagtctact
     3781 aaactaccat ttatattgaa aggtataatg actgttgaag atgctttaat ggcagtagaa
     3841 gcaggtgtgg atgcaatagt cgtatcaaat catggaggaa gagtgcttga ctgtacacca
     3901 ggagcatgtg aagttttacc aaaaattgct gatgctgtta aaggtaaagt tacaatactt
     3961 gcagatggtg gagtgagaac tggtttagac gtactaaaaa tgataggttt aggtgcagat
     4021 gcagtattaa taggaagacc ttttgtgact gcttcttttg gtggtgcaac tgatggtgta
     4081 gaaacttatg taaataaact tcaatcagag ctaagtagtt ctatgatatt aactggatgt
     4141 caaactataa aagatattga tggaaaagtt atatacaaat aaaattttat acaaaaaaga
     4201 ggaaaaatca ttttaatgta gaataattgt acaaaggggg aatttatatg agtagaaaag
     4261 cttatgaaga agccttagta gaattagaaa aatttattga tgaaagaaaa gaaataatta
     4321 aaagtgcgga ggactgtatt gataagtaca tagttgacag aacgctacct tttgattaca
     4381 aagataaatg tgtggaatgg caacaagagt tacttgatat tgcagaggca caagttttag
     4441 aagcaaatga attaagtgta ttattacaag agaaaaaaga acttgaagaa gattaaattt
     4501 tattagctaa gagtaaatca gtaatatgat ttactcttag ttttttttat ttgaataaaa
     4561 tacatctatc taattgagat aactttatta atattagatt aggcagttta aaataagcta
     4621 aagtagcatg gatgattagt ataaaaaata aaaccagttt aaaaaactgg tttaatttgt
     4681 attctttgaa tttaatatat gttttttcat ttcctctaat accattgtat aggatttaca
     4741 ttgagcagca gctaattctg ataaagcaaa tttttgagct ttatttaaaa actccttatc
     4801 tgtgctacac aattgttttg aactgtcttg tatcataagc attttgatta attttacaat
     4861 ttcaaaaaca tctcctgaat gaaatttatc ttggtacagt ttaagtcttt cttttctatc
     4921 aaaaatccat acaccatctg ttttattaat agattggata aaattatcaa catcatttcc
     4981 atccataact ggacgtatgc caattctatc tgcatttaga actggaatcg aaattttaag
     5041 gttactatta aaaatgacac ttaattcata gtatttttgc atctcatgat ttattttctt
     5101 tgttacaata tcatttacag agcaggctcc ctcttttgga tacattacac tttcaccaat
     5161 tttatacata tgctagttat acctccaaat tgaattttag atattgcaac ttaggtacaa
     5221 tgctttaatt atctaatgat taatattata acataaataa cttgacaagt caaaaatatt
     5281 aatatataat atagagttta gacttggtga tgtgtgaaac taaagagaaa aatataagat
     5341 aaaataattt aatatgttga aatattcttt tacaattata taaaaataga tactaattat
     5401 atttaataat tattagtttt tagcaaaatc tcttagttta agacttcctg cagttacaaa
     5461 tataattcca attaatatta gagctattat atttattaaa atactaccat tgtttttaat
     5521 agcatctata gtccaataaa atggtgtgaa ctttgaaaga ttagtcataa aggataattt
     5581 atccattgat ggtattagac tagagataga tatagctaga cctattaaag aataaaatgt
     5641 agatataaga cttatagaac tttcattttt aaatactcta gctacccaaa atacaaatcc
     5701 agtggaaaca aaactatttg ctagtacaat catcaataca ttcagactca aattaaagtc
     5761 ttctataatt gaaaaacata atagagcaaa agtgtataca attgattgaa taaaaaatag
     5821 tcctaaaaat atactgaaaa ttatttttat atctttatta tctgtagaga taagtctttt
     5881 tagcacattt gattttttta atgtaaataa atcagaagca agatgtgccg cattaatata
     5941 cataaaatag catatcaaga agactactaa aaatgaacct ttattcttat ctggtttgtt
     6001 atcaattata tttgtctttg tcaatttatc atctatattt ttatccactt tcaattttaa
     6061 cgatttagta ataaaagatt ctatttgtga ttctgcccaa agactaccac caccattttc
     6121 aattttaaag catttaacta caggtcgttg taatttatct atactatttg aaaaattttt
     6181 atctaaaacg aatacagcag aaaccttatt attttttaat agattcatag ccttatcttg
     6241 ttcatttaat ctaaatgaat tttcttttaa tttagaacta tttattaact tatgttcata
     6301 ctttcctgaa gagtcagata caattgctac tggagaaaag tacattgatt gatttcccga
     6361 gttgttgata aaaaaattaa gtgaaaaaat tagtataata ggaagcataa ccatattaat
     6421 taaaagagta tgatttttta gatatctttt tatatttgca atagttaatc taatcattat
     6481 taaacctccc tccatttata tttttccttt acaatagcaa gtgcaattaa tattgtagag
     6541 ataattaaac atgtgaaaat taaatttcct attgaatcta tggttttaaa tgtttcataa
     6601 ttactaaaca attctcctat taaataggta ggagataaac ttgtaagctt agtaaatgta
     6661 tcacttatca tactgaagat acctccaaaa attgtctgta aaaagagtaa tgcataaact
     6721 attgctgtac cgtatttttt actaaaaaag ctggttacaa aggtagatat tgaagtcata
     6781 aaataagatg ataaagcaca aagtaggagc aatatggcaa aattaccttt aaatgttatt
     6841 ccaagtattc taaagaataa aacatataat aataagaata taaatgaata aatccataaa
     6901 cctacaaagt cataaattaa gaattgtact ctagttatag gcatagaata aagtcttttt
     6961 gaaagtccct ttgattcact tatataattt gacaaaatat tgttcattat aaaaattatt
     7021 acaagaaatc ctagtgaaac taaagcaaag tattcataag agctctgttt aacattgtta
     7081 tttattatag aagtatcaat agaattttta ttaaataatt tagaaaaatc ttctgaactt
     7141 attttctgag aattatttaa ataaaatttt tcatggtaag tatctaatat atcttgaagc
     7201 aatattgcaa tatcatcacg agttccaagt ttttctatgt ttagagtatt tgatttttca
     7261 tttaataaac tactctcata gcctttaggt atagtaagct ttaattctgc cttagaatca
     7321 tcttttttaa ctgttaatat ataagataaa tcatttttca aatactttgt caaatcattt
     7381 gataatcttg tgttatcttt gtcatatata acaatggggg tagattctgt ttttataggg
     7441 ttttgaaaca tgctttctgt aaccatccca agaaaccaag ataaaatcag aggcaaagct
     7501 aaaaaatata ttaaattaag tataaaggag ctttttaaac tctttagcat agtttttaca
     7561 ctcatgtata atttcataaa atcacctcca ttagtccctt aaattttttc ctgttagatt
     7621 taaaaatacg tcttctaggc taggttcttc ataagaaatt ttcattattt ttgaattgtt
     7681 tttgtcaatg acagagagta tatctgtaag ttgtaatttt ttatctatat ccaattctaa
     7741 taatgaatta ttttctaaaa cagatataac acctttagta ttttttaaat caaagataag
     7801 ttgggcattt atatttttta tttccataat taattttgta tttgtagata cgagtgattt
     7861 taaataatca ttatttccaa aagcaatttc tttaccttca tccataataa aaattttaga
     7921 acaaaggtgc tcaacttctt ccatataatg ggaagtatat attacagtag tttcatgttt
     7981 tttagatata tcttttataa aattgaaaat atgatttctt gattgggggt ctacacctac
     8041 agttggttca tccaatatta atattttagg atgatttaag agtgctattc caatatttaa
     8101 tctcctttgc ataccaccag ataatttttt gacctttttc tttttgactt cagtaagacc
     8161 tgtaacttct aatgcttcaa tgattctttc tttaagtagt tttcccttta aaccgtagaa
     8221 agctccaaag tactctaagt tatcaaaagg ggtaagagtt tctataattg ctaattcttg
     8281 tggaactaac cctattatag actttgcttt tatataatct tttgataaat ctaaaccatt
     8341 gatttgaata ctaccactat ttggtaacat aagatttgta attatattta taagtgtaga
     8401 tttacctgca ccatttgggc caataagtcc aaatatctca ccttttttaa cagaaaagct
     8461 gatgttatca agtactaatt tatcattaaa tctttttgtt atattattta ctctgactat
     8521 atccatagta atccctccaa aataattttg tataagttaa aaagctataa tattataata
     8581 aagaattgtg aattataatt ctattactat aagtcactaa aaaaagtgac ttaagtcact
     8641 ttatattttt agatttattc tattacaatt ttatttttga aagcaaagat tgctagttga
     8701 gttctgtcac gaagttctag tttagctaaa atattagtta tgttattctt tattgtacct
     8761 tcagataaga atagttcttg acttatttct ttattattaa gtccatttgc aattagtcta
     8821 attatagata tttctttttc tgttaaattg tacatgtcat aaagatgctc ttgtttaatc
     8881 gttttttcag aggtcatgat tttttcagct acacttttat caagcacaat attgccaaaa
     8941 aatgaagaac gaatcccttc atgcaatact tcatcagagc tatcttttaa aaggtatcct
     9001 gaagcaccaa acttcatagc atcttttata tattcatcat cattaaaagt tgttaaaatt
     9061 aataatgtta tagaattatt atattccttt ataagccttg tacctagaac cccatcacat
     9121 actttcattc gtatatccat aagaactatg tctacatcat tcattttaca aaattctaaa
     9181 gcttcatatc cattagaagc atctcctaca atttctaaat cattataaga tgataatata
     9241 attttaagac cttttctaat taatttttcg tcatctacta taagaacttt aattttattc
     9301 aaaaaaatca ccccctgaaa atttaggaaa agaagctcta attgtgaaac cattattaga
     9361 attatcaaat tcaactttac catttaattc atatattctc tcattgatac tattaagtcc
     9421 atttcctttt tttatattgc cacatcctat accattatca ctaatagtaa ttataagatt
     9481 tgaagtattg aatgtaataa aaattctgat ttcagttgcc tttccatgca tcgatgagtt
     9541 ggaaagggat tcctgtataa gtctatataa agctatagat tgatttctgg ataagttcca
     9601 agtatttttt gaaatagtta atttaacatt aatatttgta agcttaataa agcttttaac
     9661 taattctttg attttaaata aactttggta attttcatat tcaacaggtt ttaactcaga
     9721 tatagccctt cttacatctt gaaaactttc agttacaaat tctctaagtt catgtactaa
     9781 gtcataaatt agaggtttgt cttttaagag tttttctata gcatttaatt gtattattgt
     9841 tgtagaaaga gaatgtccta cactatcatg tatttctctt gatattcgat ttctttcttt
     9901 taaaattgct aattcttcta tagaacttgc ataagtttcc aaatcagcat taactttttt
     9961 taattcatct ttagaaattc taagcttatc ataaagattt tgactgtata attttgataa
    10021 attctcattt tctatatata tagaaagtac agttataatt agcaatatag agcttgactc
    10081 cagtgccaaa tatatatttt tatctaaact aataataaga gaagatatta taacaaaaga
    10141 gaacaatatg tacttatatt tttcctttat taaaaatgat atatctaata ttaaaggaac
    10201 aaagtaaatc gaattaaaag tttttgtata attacaaagt ataaaaatta atataagttc
    10261 taaaaagtaa gaaataagta taaatttatt ctcatttgat aaagaaaaaa atctaacttg
    10321 attatttatt ataattagaa ataatattat catagttatg accggataca atgtattttc
    10381 aacatttttc aaatagctta caactaatat aaataaagat aaatatcgta taaaagcaac
    10441 taatttttct ctgttcatta aaggcactcc tccaaaaaaa taaacttttc ctatgaaaac
    10501 tagaataata tcataaaaga ataaagtcaa tagaagtatt tattaatatt gatggaaata
    10561 aaatcaatcc aaaaacttga atagtaaaat tgtatactga ccataattta aaagtgaaaa
    10621 tttaatgtat tggagtgaat aatgaataat aaagaaaaag gtgattttgg agaaaaagta
    10681 gcagttaatt atttgctatc aaaaggagca aagatactag aaaaaaatta cagattaaag
    10741 ataggggaaa tagatataat agcaaaaatg gaagatgaaa ttatatttgt ggaggtgaaa
    10801 tcaaggtcta acataaagtt tggctaccct tgtgaatctg taagcttcaa aaaaagaaaa
    10861 aagataattg gagttgcaaa ttattatatt ataaaaaata acttaaataa cactcccata
    10921 agatttgatg ttatagaggt atatttatta gaaaaaagaa taaatcacat aatgaatgct
    10981 ttttaaaaaa gataatgttt ttggaaagga ttaaatatgt taagtattat taattcaagc
    11041 aacttagtag gaatcgacag ctttttagtt aaggttgaag tagatgtaag caatggaata
    11101 cctagtttta atattgttgg tcttccaggc aaagaaatta aagaagcaag agaaagagta
    11161 aagtcagcaa ttcttaatag tggatataaa tttccaagca cgagaatagt tgtaaattta
    11221 tcaccagcag atataaaaaa agaaggagct tttttagatt tatctataag tataggcctt
    11281 ttaagagagt taataaaaaa agatgaaaat tacataagag aaagtatgtt tataggagaa
    11341 ttatcattag atgggaaaat aagaaaagta agaggtatat tgcccataat tatgggtgca
    11401 aaaactcaga acataaaacg tatttttata ccaattgaga acataaaaga aagtctattt
    11461 gtagatgaaa ttgatataat tcctattaaa agtttaaaag aatgtgtcga ttttttaaac
    11521 gaagagataa aagtcgataa agtaaggata atgtcttttt tggatgataa gtcaagaaaa
    11581 gagaacgaag aattagaaaa agataatagt tatatagatt gcaaatatac taagattaat
    11641 aatgaagaaa gtaaatatga tgaagacttt aaagatgtaa aaggaaatta ttttgtaaag
    11701 aggagtgcag aaattgctgc tgctggaaat cataatatgt ttatgattgg acctccaggc
    11761 tcaggaaaaa ctatgattgc aaaaagagta aggacaattt taccagatat aagtgtagaa
    11821 gaaatgatag aagtaagtaa ggtctatagt atattgggta tgataaatga aactaaagga
    11881 ataattgata aaagaccttt tagagcacct catcatacaa ctacaaagca atctttaatt
    11941 ggaggaggaa tggatgcaag acctggagaa attgctttag cacatagagg tatcttattt
    12001 ttagatgaga tagccgaatt tgatagaaaa atacttgaga ctttaagaca acctatagaa
    12061 gatggatatg taaatatatc cagagtaaag tacagtgcaa aatatccttg tagagtactg
    12121 ttagttgcag ctatgaatcc atgtccatgt ggttattata tgtcagagac agagtgtaga
    12181 tgtagaagta acgaaattga tagatacata aataaaatat caggtccatt gttagatagg
    12241 tttgatattt ttgtagaagt taattctata aaatattcag attttaattc tttaaaacaa
    12301 gaagaaagct ctcaaaaaat aaagagaaga gtagaaaatg ctagaaaaat acagataaat
    12361 agatttaaga aagataatat aaaaaataat agtgaaatta aagcttacaa tttatttaaa
    12421 tattgtaaac tggaaaaaga agcttcaaaa acggctgaga tgatatttag taaatacaac
    12481 ctaagcagta gaagttatac aaaactttta aaaatggcaa gaacaatagc agatttagaa
    12541 gaaagagatt tgataaattc acagtgtatt atagaagctt tttcatttag aaaggcttat
    12601 tatagttatt ttaaatagtt ttttgaggtg gattttatgg aaaaaagaga tacttattta
    12661 tggttaaaat caattggtgg aataacaaca aaaacaattg aaataataga aaatgaaata
    12721 gtaaatattg aagatatatt tgatttttct gaaaaagaaa tatataattt aaaaaatata
    12781 agcttgaata ttagaaaaaa tatagtaaaa tatagaggtc acgcttattt agaaaatata
    12841 aaagaactac tttacaaaaa agcgattaaa tatatttgta aatatgataa agaatatcct
    12901 gaaaatttaa agaatatata caacgctcca aagttattat tctacaaagg tgacataggc
    12961 ttagttaata ataattttaa tatagctata gtaggttcaa gaaaacctac agcctatgga
    13021 attaattgtg caaaaacaat aagttgtcaa ctatcccaat atggagttaa tatagtaagt
    13081 ggattagcta taggaataga tgcatactcg cacataggtt gtatgagtgg aaaatctaaa
    13141 actatagcag tacttggttc aggagtagac aatcctcttc caaaacaaaa tttacattta
    13201 tcaaataaaa tattagaaaa tgggggatta ttattatcag agtataatat taactcgaca
    13261 gtagccccgt accatttttc taatagaaat agaattatca gtggtttaag tgatggagta
    13321 gttgttgtag aagcagcaat aaaaagtggt gcactaatca cagtagattt tgctcttgaa
    13381 catggaaaaa atgtttttgc aatacctggt aatataaatt ctcaaatgag tagaggttgt
    13441 cataaaatta taaaagaagg tgcaaaatta attgaaaata tagatgatat tttaaatgaa
    13501 tataacatat ttaatattat tgataaaaaa ataaatcaaa aatatgataa tataagtcta
    13561 aatgccaagt ctaagcaaat aattgaagct ataaaaagag aaggaaactt gcatatagat
    13621 agtatttgtg attatactgg tatagaaata aagtatgtaa attcaataat caatgaatta
    13681 gtactaaatg agttagtagt agaaatgaat aataaaacgt acagtttaaa tgtataaatt
    13741 aagattaggt agtgggggtg tatggtttta tggccaaaac attagtcatc gtagaatcgc
    13801 ctgcaaaagc taaaactata gaaaaatttt tagggaaaag tcattacaca gttaaagcat
    13861 cagttggtca tgtcagagat ttacctaaaa gtaaattagg tgtagatata gaaaataatt
    13921 ttgaacctca atatataaat ataagaggaa aaggcgatgt aataaaagaa ttaaaaaaag
    13981 aagctaaaaa atctaaacaa gtatatctag caactgaccc tgatagagaa ggtgaagcta
    14041 tatcatggca tttagctcat atactaaatt tagatgaatc tgaggattgt agaatagagt
    14101 ttaatgagat aactaaggat gcaattaaaa aagcaattaa acatcctaga aatattgata
    14161 taaatttggt tgatgcacaa caggcaagaa gagtgctaga cagactttta ggttatcaaa
    14221 taagtcctat attatggcaa aaggttagaa aaggtcttag tgcaggtaga gtgcaatctg
    14281 ttacaacaaa gttaatttgt gatagagaaa aagaaataaa ggcatttatt ccaaaagaat
    14341 actggacaat agatgttgag gctaagacag taaaagacaa agatataact ttgaaatttt
    14401 atggtaaaaa tgatgaaaag attgaattag aaaatgaaga agctgtaaat gaaatactaa
    14461 aagaaatgga aggtaaagat ttaaaggttg agaagataga atctaaatca agacgtaaat
    14521 cagctccaaa accatttaca acaagtatgc ttcaacaaga aggagcaaat aagttatttt
    14581 ttactactaa aaaaacaatg atgatagcac aagaattata tgaaggtatc gacatagaag
    14641 gtgaaggtac tgttggtctt atatcatata taagaactga ctctaaaaga atatctgatg
    14701 aagcaaaaga aaaagctaag ggttatatcg taaacaattt aggagaaaac tactataaaa
    14761 acattggtga taaaaaagaa aaaaaggata ctaaaaaggt tcaagatgcc catgaggcaa
    14821 taagaccaac ctcagttgat agaactcctg agagtataaa agcctcattg agcaaagacc
    14881 agtacaagtt atacaattta atttggagaa gatttgtagc tagtcaaatg gaagattcag
    14941 tgtttgatat actaaatgta gaatgtaaaa taggcgatat tgtatttaag gcaactggtt
    15001 caaaaatgaa atttgatggt tataccaagg tatataattt ttcagaaaga gaagacaaaa
    15061 ttttaccaag tatagaaaaa ggagatatat taaatataga aaatatattg ccagaccaac
    15121 attttacaca accaccagca agatatacag aagctagttt agtaaaaaca ctagaagaac
    15181 taggtatagg tagaccaagt acgtatgctc caacaatagc tactatactg aatagagagt
    15241 atgttgaaaa gcaaggaaca agtctatgtc caacagaact tggaataata gttactgata
    15301 ttttggaaaa taatttccat aaatttatag atgtagattt tactgctgat atggaaagta
    15361 aacttgatgt tatagaagaa ggcaatacag attggaaaaa gattgtatca gaatcatatg
    15421 caccacttaa agaggctatt gaagaagctc ttgaaaatat agaaaaagta aatatggatg
    15481 aagaaactga tgagatttgc gagaactgtg gttctaatat ggttatcaaa tatggtagat
    15541 ttggaaagtt tatggcttgt aaaaactatc ccgattgtaa aacaactaga ccaattatga
    15601 ataaaattgg tgttaaatgt ccaaaatgtg aagaaggaga tattatactt agaaaatcta
    15661 aaagaggtaa agctttttat gggtgttcta attatccaaa ctgtgacttt gtagcttgga
    15721 ataagccaac aggagagttt tgtgagaagt gtggttcata tatggttgaa aaagtgacta
    15781 aatctgaaac aaaaacagtg tgttctaata aagaatgtaa taaagagaca aaagagcata
    15841 atgacggaaa agagtgaaaa ttgaaaaaaa tcacataatt ctcttgaaaa aggttccaat
    15901 ctatgataat ctttcaagtg taaacaacta atagaaaaat aaattttcat taaatgtgaa
    15961 aataatatta gaaaatataa aaggttatta aaaggcctaa atttcatgag gagatgatta
    16021 aatggcaagt gaagtgttac aaaaaacaag gaaaataaat aaaacattac aaacaagtgg
    16081 tggaagcagt gtctcttttg atttactggc cggagcattg ggcgacgttt taagttctaa
    16141 tgtttatgta gtaagtgcaa aaggtaaagt actaggtctt catttaaatg atgttcaaga
    16201 cagttcagtt atagaagatg agtatactaa gcaaaagaaa ttttcagatg aatatactca
    16261 aaatgtgtta aaaattgatg aaacattaga aaatttaaat ggtgagaaga tattagaaat
    16321 ctttcctgaa gaacatggaa gattacaaaa atatactaca gtagttccaa tattaggaag
    16381 cggtcaaaga ttaggaacat tggtactttc aagatattca aattcattca atgatgatga
    16441 tttagtaata gctgaataca gtgcaactgt tgttggtctt gaaatattaa gagcaatagg
    16501 tgaggaattg gaagaagaaa tgagaaagaa agctgtagtt caaatggcaa taggcactct
    16561 gtcctactcc gagcttgaag cagttgaaca tatttttgct gaattggatg gaaaagaagg
    16621 tttacttgta gcaagtaaga tagctgatag agttggtata actaggtctg taatagtaaa
    16681 tgcacttaga aaatttgaga gtgcaggtgt gatagaatca agatcattag gtatgaaagg
    16741 tactcatata agaatactta atgacaaact tacagatgaa ttaaaaaaat taaaaaacaa
    16801 tcaataatct atattttata ggtttagatt agaaaaggta tctatttcaa atagatacct
    16861 tttttagacg aattattaag gtaatgataa gtatattaaa aaggagtgag aaaatgcctt
    16921 tagcagataa aataagacca aaaacaatga atgatgtaat aggtcaaagt catataatag
    16981 gtaatggaaa aatattgtct aagatattac aatctaattt tttaccaaat atgatatttt
    17041 ttggtcctcc tggtgttggt aaaactacag tagcggaaat aatagcagaa agaagcaata
    17101 aaagcttcta taaaataaat gctactaatt catctttaga agatataaaa aaggtgatat
    17161 cagagcttgg aagtataaat aatgtaaatg gagtcctatt atatatagat gaaatacaaa
    17221 gttttaataa aaaacagcaa caatcaatat tagaatttat ggaaaatggg agtataactt
    17281 tgattgctag cactacagaa aatccatatc attatgtata taaagctctt ttaagtaggt
    17341 ctactgtatt tgaatttaaa cctttagaaa aacttgatat agaaaaagga ctgaaaagag
    17401 ctgttgaagt attaaatgaa gatagctata tggatattga gtgtaataat gatgctattg
    17461 aagatatagc aattctttct gatggagata tgagaagagc cttaaatatt ttggaagtgg
    17521 tagtctattc aactaaacca aataaggata atataactta tatagattca gatgtaataa
    17581 gggcatctac atttaataaa attataaact atgacaaaaa tggtgatagt cattatgata
    17641 ttttaagtgc atttcaaaaa tctataagag gaagtgaccc acaggcatct atacactatc
    17701 tagcaagact tataaaaggt ggggatttga taagtatatg taggagactt ttagtaatag
    17761 ctagtgaaga tataggttta gcttatccaa atgctattgt aattgtaaag gcatgtgtag
    17821 actcagctat gcaacttgga tttccagaag cgaaaatacc attagcagaa gctactattc
    17881 ttttggctac atctccaaag tctaattctg catgtatagc aataatgaaa gctatggatg
    17941 aactggataa agagtttgtt aaggatatac caaatagtat aaaggatgct cactattctg
    18001 gttctaaaga aataggtagg ggttgtggat acaaatatcc tcataatttt aaaaatcatt
    18061 atgtaaagca acagtattta ccagatagca taaaagatag tatttattac ataccacaag
    18121 aaaataaaac tgagaaaaat ataaaaaaat atttagaata tctaaatagt gatttttaga
    18181 ctgaacttta tgtatcgggg gtagatatta tgattataaa acttaactca acttatcaca
    18241 gtagagttat gaaatactta aaaaaagaac ctgagtacaa tttgtttata ataggggata
    18301 ttgaaagata tggatatgga aataattttt taaatatatg ggcagatgtg ggtgaacatg
    18361 gtgaaataaa ggcaatatta cttaaatatt ttgaatttat gatgttttat tctgatggag
    18421 agtatgatgt tgaaggtttt tataatctac ttcgtaatac taattacgaa gaaatatctg
    18481 ggaaaatatg tgctgtagat gctttagcaa agagattagg acttaataat ttaaaggtag
    18541 ttgatttttg caaacttcaa actaaaaagt ttttgataga taataattgt aatgcaaagg
    18601 ttaagagaat taggcttgga aatctaaaaa agacagtaaa actttatgac ttaatagatg
    18661 aatttcacag tacaacttta gagaatttaa aaaatggact aaggacaggt agaggatatt
    18721 gtatagagat taacaaacag gtggtgtcaa tggcaaagag tacttcagaa aataggactc
    18781 atgcaatgat aattggagta ggaacacatc ctaaatatag agctaaagga cttgctacaa
    18841 aatgcctaat taaactatgt tcagagttac tgagagaaaa caaaattcct tgtttgtttt
    18901 atgataatga agaggctgga aagatatata aaaaactagg atttgaaaac attggaaaat
    18961 ggggaattta ttcaaaataa aaaattaaaa ttaatcttga caaaattagt agggtataat
    19021 aaaattatct tgaaagtaat tcctactaaa acagtatgaa ttagatttct atatagaggt
    19081 gataatatat gaagttgtct actaaaggta gatatggact aaaagcaatg tttgaattag
    19141 cattaaatca agacaatgga ccagtatcat taaaatttat tgctaagaag caaaaaatat
    19201 cagatcagta cttagaacaa atattttcat ctttaaaaaa atcgggtcta gtaaaaagtg
    19261 tgagaggtgc tcaaggaggt tatttgcttt caaagaatgc tgaagacata acagtaggag
    19321 atatacttgt agtattagaa ggaccagttg cattatctga ctgtgtacta gatgaagatg
    19381 tatgtgaaaa ctcaaacatg tgtgtaacaa aaatagtttg ggaaaagatg aaaaagggta
    19441 tagaagatgt tatagattca attactctta aagatatgat aaatgactat aacaaaaata
    19501 aattagaaaa tgatataaca aatattaaaa aatagatttg gagatgaatg taatggaaaa
    19561 aagaagattg tatatggatt attctgcaac aacacctatt aaaaaagaag tattggatgc
    19621 aatgatgcca tacctaacag attattttgg taatgcatct agttttcaca cattcggaag
    19681 agaagcaaaa gatgctttgg ataaagcaag agaacaagta gcagccctta taaatgctga
    19741 acctagtgaa atatatttta cagcaggtgg ttcagaaagt gataactgga cactagaggg
    19801 tgtagcttat gctaataaaa acaaaggtaa tcatataata acttcaaaaa tagagcacca
    19861 tgcaatactt catacatgtg aatacttagc aaaacatcat ggatttgaaa taacttattt
    19921 agatgttgat agcgaaggaa aagtagactt aaagcaacta gaagattcaa taaaagatac
    19981 tactatactt ataagtataa tgtttgcaaa taatgaaata ggaactatac agcctattaa
    20041 agaaatatcc gaaatagcta aaaaacataa gatattattc cacactgatg cagtacaagc
    20101 tacaggtaat attccagtag atgttaaaga attaggaata gatttgatga gtatgtcttc
    20161 acataaaata tatggaccaa aaggtgtagg agctttatac ataagaaaag gtgtaagact
    20221 tcataacttt gtccatggtg gagcacaaga aaaaagcaaa agagctggta cagaaaatat
    20281 acctgcaata gttggatatg gaaaagcagc agaattagct aaggaaaata tgcaaaatca
    20341 tgtagaaact ttaactcgtc ttagaaataa gttaatagat ggtgtgttag aaagaatacc
    20401 ttacacaaga gtaaatggta gcttagaaaa tagattgcca ggaaatgcaa actttgcatt
    20461 ccaatttata gaaggtgaag gaatactttt attattagat atgttaggaa ttgctggttc
    20521 aagtggttct gcatgtactt ctggttcatt agacccttca catgtacttc ttgcaatagg
    20581 tttaccacat gaaatagcac atggttcatt aagacttaca gttggagatt ttacaacaga
    20641 tgatgatata gattatatac tagagaactt accaaaagta atagaaagac ttagaagcat
    20701 gtcaccactt tatgatgatg cgaagaaaca aggtttagta aaatagacat aaagataaag
    20761 cataaaaaat agacataaat tgagtaggag gaaaagataa tgcaatatag tgataaagtt
    20821 atggaacatt ttatgaatcc aagaaatatg ggagaaattg ataatgcaag tggtgtaggt
    20881 gaagttggaa accctacatg tggagatata atgaagatat ttttagacat agatggagat
    20941 gtaataaagg atgttaagtt taaaacattt ggctgtggtt cagctatagc aagttcttct
    21001 atggcaactg aaatgataaa aggaaaaact ataaaagatg cattagaact tacaaataaa
    21061 gctgttgcag aagctttgga tggtttacca ccagtaaaga tgcattgttc agttttagct
    21121 gaacaagctg taaaagcagc tcttatagat tatgctcaaa agaacaatat ccatatacca
    21181 gaattggatg gatatgttat agatgatgct catgaccatg atgttgaaga agaagaataa
    21241 aaataagtga ttgtgttatg agaagtttac aatgattaaa aagaagtact aatgatataa
    21301 ttaggacata aaaaatagct gtttttaaaa tagctatttt ttattgccta aattaagtat
    21361 tttaacttga tttagaggtt aattagttaa caaaataatc cataagattc aaataataaa
    21421 gatgattatt tttttagaaa atagaacaag ctatatttta aataagtaca atacttgctc
    21481 tatatggtat aataataagt aatgcaaaag atgaggtgaa atttgtttat gaataaaaaa
    21541 gtaatgatag gtatgagtgg aggagttgat agctctgtag ctgcatatct tttaaaacaa
    21601 caaggatatg atgtcattgg tgttactatg aagttgtggc aagatgatga tgttgttgaa
    21661 attgaaggtg gttgttgctc tttatctgct gttgaagatg ctagaagggt agcaaataaa
    21721 ataggtatac cattttatgt tttaaatttt agagaagtgt ttaaagaaaa agtaatagat
    21781 tattttatag atgaatattt ggaaggaaaa actcctaatc cctgtatagc ttgtaataaa
    21841 catataaaat ttgatgattt ttataagaag gctagacaaa taggttgtga ttatgtagct
    21901 acaggtcact atgcaaagat agaaaaggat gaaagtacag gaagatattt gctaaaaaaa
    21961 tctgttacag ataaaaaaga ccaaacttat gcactttata atcttacaca agagcaacta
    22021 gagcatactt tattgccaat aggtgactat gaaaaagata gagtaagaga aattgctaag
    22081 gaaatgggta tggcagtaca caataagcct gatagtcaag aaatttgttt tgttaaagat
    22141 aatgactatg caaattatgt aaaaaaacat tctaaaaagc gtattgaaga aggttttttt
    22201 gtagatacta aaggcaatat acttggaaaa cataagggta tattatatta tactataggc
    22261 caaagaaaag ggcttggaat tacttttgga aaaccaatgt ttgtaataga cataaatcca
    22321 ataaataata ccatagttct tggagacaat gaagatttat ttaaaaagga acttattgct
    22381 aaagatgtta actttatatc aatagatacg ttagaagaac ccttaagagt tcaagccaaa
    22441 ataagatatt cagcaaaacc atcaccagct actattcata gagtaggaga agatactatt
    22501 aaaatagttt ttgatgaagc tcaaagagct attactaaag gtcaatctgt agtaatgtat
    22561 gatggagata ttgtagtagg tggaggtata atcgagaaaa gtttataaaa acatctaaaa
    22621 aattaaaaaa ataagcaata aagtatatta agagtaaata aagtttataa aataaattta
    22681 ttgtatatga aaatatagta ttgattaatt ttgtaaaatt tagtaatata attagtatat
    22741 taattaaaaa acaaatacag tgataaggaa tagtaaaata tttgatgtct tacagagaga
    22801 gggaaatgct ggaagccctt agaatatgat atttgaagca gccttttagt agcaatcttg
    22861 aacaatttat cttttataaa gaagatttaa gtagagattg acggtagtta cgttatagct
    22921 aaggttttcc gaagatatca tactttgtat gataattagg gtggtaccgc gattgtcctc
    22981 gcccctataa atttatttat agggacgagg ttttttattt aaacgaaaaa ataaaattta
    23041 ttaggaggaa catgatatgg aaaagatggg attaaatgaa ataagaagta agtttttaga
    23101 attttttgag tcaaaaggtc attatgtagc aaatagttat tctttagtac caaacaatga
    23161 taagagtttg ttacttataa actcaggtat ggcacctttg aaaaactact tttcaggtgt
    23221 agaagtacct ccaagtgtga gaatgtgtac atctcaaaaa tgtataagaa caggagatat
    23281 agaaaatgta ggtataactg caagacatgc tacattcttt gaaatgatgg gtaatttctc
    23341 atttggagat tactttaaaa gagagtcaat aaaatgggga tgggaatttg ttacagaatg
    23401 gctaaatata ccagaagata agatatgggt gactgtatat gaagaagatg atgattctta
    23461 tgatatatgg gcaaaagaaa tgaatttccc agaagaaaga atggttagac ttggaaaaga
    23521 tgataatttc tgggaaatag gtacaggtcc ttgtggtcct tgttcagaaa tatattttga
    23581 tagaggagaa gaatatggat gtgacaatcc agactgtaaa ccaggctgtg attgtgatag
    23641 gtatttagaa ttttggaacc atgtatttac tcaatttgat agagatgaag aaggaaatta
    23701 tagtctatta gaaaacaaga atatagatac aggtatgggt cttgaaagaa tgggatgtat
    23761 tatgcaaggc gtagacacta tctttgaagt tgatacaatt aaatctatac tagaagcagt
    23821 tgagaagtta acaggagtaa aatatggaga gaatccaaaa aatgatatat caataagaat
    23881 aataactgac catataagag ctgtaacatt cttagttagt gatggagtgc ttccatcaaa
    23941 tgaaggaaga ggatatgttc ttagaagact ccttagacgt gctgctcgtc atggtaagtt
    24001 attaggagta aaagaattat ttttacagaa actaatagat gaagttataa aagtaaatga
    24061 taaagcatat ccagttttag ttgaaaaaga aagttatatt aaaaaagtag ttggaataga
    24121 agaagaaaaa ttcaatgaaa ctatagacca aggaacagaa atattgaact cttatataga
    24181 agtattaaaa aatgaaggaa agactgtcct aagtggtcaa gaagctttta aactatatga
    24241 tacttatggc ttccctatag acttaactaa agaaatatta gaagaagaac atctatctgt
    24301 agatgaagaa gcttttaatg aagaaatgga aaagcaaaaa gaaagagcta gaaatgctag
    24361 aggaaatatg gatggagaaa gttggaagga agaccctcta tcaaaattag aatctacagt
    24421 tgacagtaca tttaatgggt atagtgaaat ttatggtgaa ggaactattg aagctatagt
    24481 taaagatgat gagctagttc aaagtgcaga agaaggcgat aaggtatcta tagtactaga
    24541 taacactact ttctatcctg aaggtggagg acaagttgga gattgtggat tgataactaa
    24601 tgaaaactta gttttagaag tattaaatac taaaaaaggt gctaataata gtataaaaca
    24661 tataggtata ataaaatcag gaagaataag taatggggac aaagtgaaga cactcgtaga
    24721 tagagaaact agaatgtcag ctgcaagaaa tcacagtgct acacatttac ttcataaggc
    24781 attaagagaa gtattaggag aacatgttaa tcaagctggt tctttagtaa ctccagaaag
    24841 acttagattt gatattactc actttgaagc gatatcaaat gaagaattaa aagtaataga
    24901 agaaaaagta aataatgtta ttttatcatc tttagacata aaatgtgata ttatgaatat
    24961 aaaggaagct aaagaaaaag gagctacagc actatttggt gaaaaatatg gtgatgaggt
    25021 aagagtagtt tctatgggag attattctac agaactttgt ggaggaactc acttgacaaa
    25081 tacttctcaa gtaggaatgt tcaaaatatt atctgaaggt ggagtagcag caggtgtaag
    25141 aagaatagaa gcaataacag gaaaagctgt ttatgaatac ctaaaagaaa gagatggaat
    25201 tatctctgaa gtttgtgtaa acttaaaatc taaagaagat aatttaattc aaagaataag
    25261 ttctttatta gaagaaaata aaaacttatc taaagaattg catgatatga aagctaagat
    25321 gagtttacaa tcagttgatt ctatttttga ttctaaagtt gaagtaaatg gagttaattt
    25381 gataactaat aaatttgaag gtatggatat ggatacacta agagaaacag cagataatct
    25441 aagagataag cttggttctg gtgtagtagt acttgcaaat gtagtagatg ataaagttaa
    25501 ctttgtagtt actgccacta aagatgtatt agataaggga atacattcag gtaatattgt
    25561 tagagaagtt gcaaaaatag ctggaggaaa aggtggagga agacctaata tggcacaagc
    25621 aggagctagt gatgtatcta aggttgacca agctttaagc tatgcaagtg aggttattaa
    25681 gacacaagtt aaataacatt cactcaagga ggtttttagt ttggaaaaag atttagacta
    25741 cactatgaaa tttgaaggaa taccagaaga taggatgagt gtaggagata ctattgattt
    25801 tgtatataaa gcattagttg aaaaaggata taaccctata aatcaaatta tagggtatct
    25861 cctttctggt gattctagct atataactag tcataaaaat gcaagagcta taattaaaaa
    25921 atttgaaaga gatgagatac ttgaagaagt aatcacgcac tatctgaata gaaagtaggt
    25981 caaataaatg agaaaaaaga ttatgtcgtt gtttgcaata gtcattatga tttttgtatc
    26041 aactgctagc tatggttttg ctgaagaaaa aggcaaggtc atatttattg atatgaatag
    26101 gaccaatctt ggaagtatga tgaatattcc aatcttgaaa aatgagatag aaaagagagg
    26161 ctatgtagct ctcatgaata taagagggga tcaaggtact gatgatagaa ggtcttatgc
    26221 aagtatgggt gcaggaacaa gagctagtgt aactactgaa gactatatca attttcaaaa
    26281 agtagaccaa gatactgcta aagcttttga agtcgcaaca ggtcaaaaag ctaaagaaat
    26341 aaatgattta ggcattaata gatctataaa tgaaaatctt gagtatggag aatatggagc
    26401 aaatttaggg tcattaggaa aaactttatc agaaaatggt ttaaagacat ctgtaattgg
    26461 aaatgctgat ataattgaaa ataatcaatt agttaaaaac agaaacttat gtttagtagc
    26521 tatggaccaa tatggaagga ttgattcagg taatattgat aatattaata agaaagattc
    26581 taaaatgcca tttggaatat ctacagatta tgataaatta ctagatgaaa ctaaaaaatc
    26641 ctataaaaat agtgatgcta tatttgtaga acttggagat acatatagat tagatatgta
    26701 tagattaaat ctaaatgata atacttatga tataatgaag aaaaatattg taaaaaatat
    26761 aaataaatat cttgaacaag tattttctat ggttggagaa aatgacactg tttatatagc
    26821 aagtgcattt ccaagtgacc tagattataa gaataagaga agactttctc caataataaa
    26881 atttagtgga gaagggaaag gtctactgga atctgccaca acaagaaagg ctggaattgt
    26941 tgccaattta gatgttggag tagatatact aggtacattt ggtcttgaaa ataaagagat
    27001 ggtaggtaga agttatactt tagtaaataa agaggacaat attagctatc taaaatcact
    27061 ttatgaaagg atagtgtcta tatcttcaat aaggtcaact attataaatg gctttgtagg
    27121 cgtaatatct gcttcttggg taattgccat gtttgcgatt ttctttagaa attatatgcc
    27181 acataaagag cgtgtattca aagtacttaa ggagtttata aaattaggca taataatgcc
    27241 actatcattt atgttagctc ctttgatgaa ttttaaaact ccaatttcaa tatctttggg
    27301 aatatttgca actacgctaa tattatactt gttaggtaga aaattattta aggacaatga
    27361 tataaagcac atgggatttt ttgcaacact tactatttta gtcatagtta tagattctgt
    27421 atttggaaca tacttaatgc aaaataacat aatgagttat gatgctgtca taggagctag
    27481 gtactatggt gtaggaaatg aatatgaagg tgtaactata gcaagtgcag tatttggctt
    27541 agcagtatta ttacattata agaaggtatc taaattactt gttgtaattt tttcattaat
    27601 aatacttata actagtgcat atccttcaat gggtgcaaat gttggtggag ctatatcaga
    27661 atgtgtagca tatttgttgt ttataatgct tatatatgac attaaaatag attttaagaa
    27721 agctgtatta ttagctgttt cagctgtagt tgtcgttttt gcatttgcag ctttagatat
    27781 actttcaggt agtgaatctc atttaggtat gtttgtacag agaattttcc taaatggacc
    27841 aggagagata ttacaaacat ttggaagaaa aattcaaatg aatatgcaac tagcacagac
    27901 aagtgtatgg gtaaatattt tacttgtagg aattggagta attgcagtgc ttatatttaa
    27961 accatctaga cactttagaa agataatgaa taattttcca atcttgttta aagggtttat
    28021 tgcatctatg gttggttgta taattacact tttagttaat gattctggaa tagttgctgc
    28081 atctacagca tctatatata tacttatacc actaataata ataagtataa atatgataat
    28141 atttgaaaaa aataactaaa aaaattttta ctgttcatat aggatttaaa taaaaaatgc
    28201 aatatgatta ttaatgtaaa ctggatgctt acataaaaaa tcatattgca atttttatga
    28261 ttgattatgt aaaattatat gaagcagtaa gcctgtgacc ttagttatga gaggttcaga
    28321 atatgtattt aatctataga atataaatag ataaaggagg aactatgtta gatggaagaa
    28381 taatgggtct tgatgttggt gataaaacta ttggagttgc tgtgagtgat ttgatgggat
    28441 taactgcaca aggtgtaaaa acaataaaaa gagttggcaa gaaaaaagat attgaagagc
    28501 taaaagcaat aataaaagaa aaacaagtaa ataaaattgt atcaggatta ccaaaaaata
    28561 tgaatggaac tttaggtcca caaggagaaa aagtaatcaa gttttgtgaa ttggtaaaag
    28621 cagaaacagg tattgatgta gagttttggg atgagaggct ttctacagta gcggcagaga
    28681 ggtctttatt agaagcagat gttagtagac aaaaaagaaa aaaggttata gatatgttgg
    28741 cagcagtaat aattttgcaa ggatatttag attttaaaat aaattcataa aagaactata
    28801 aaattgaata cttatgatat ataatataaa taataaaaat aaaaataaat ttgaggtgaa
    28861 tgacattatg gaagaaaata taataaattt aatagacgaa aatggcgttg aaagccaatt
    28921 tgaaataata ttaacattag aagcagaagg aaaagagtat gcaatattaa tgcctttaga
    28981 tgatgaagaa gctgaagaag ctttaatctt tagaattgat gaggatgaag aaggtgaaat
    29041 cttaatacct ttggaaagtg atgaagagta tgaaactgtt gtagctgtgt atactgctat
    29101 aatggaagaa gaaggtttaa attacgacga agatgaatca aatggactta actagataag
    29161 taattaagtt tgtatataaa aatcagatat ttattatatt tgctttaatt aaacattatt
    29221 aattgtaaaa gcatttatag tatatatctg tttttttgtt ttttattaaa aataccaaaa
    29281 aatttatgaa ttttggtgaa taatatatct tttatgggta tatatttata ttatgagaat
    29341 aaattaaatt tatttaaatg tcttgacaaa aaatgaatta tcaattacaa tattatttaa
    29401 taaagattat caattgaaaa tagtaagggt gatgttatgg caaatacaat ggatttatta
    29461 aaagacaagt taaaagaaac tggttttaag attacgccac aaagaagagc aatagttgaa
    29521 atattgctta aacatgacca ttcacatcta agtagtgagg aaatctatga tttagttagg
    29581 gttgactgtc ctgaaatagg cttagctact gtatatagaa caatgcagct attggatgaa
    29641 ataggattaa tatcaaaact aaacttagac gatggatgta taagatatga gattagtcta
    29701 cataaagaag actgtcataa tcatcatcat cttatttgta aaaattgtgg aaagataatg
    29761 gaagctaaag aagacctttt agacaatata gaaaaagaga tacaatcatt gtacaaattt
    29821 aaaatacttg atcatgatgt taaattttat ggactatgtg acgagtgtaa tggagtaagc
    29881 gattcagaag aataaacttc tattgcttaa tgtcgatgga agaatagtat agaactttta
    29941 tattctatgc tattcttcca ttttttatta taaaccatct ataaaatgca aatatacagt
    30001 tttcaagatg cttatagttt taatattgaa aatataatta atcctataag tacaaaaatg
    30061 aatgattttt ctatgaaatt actaaatggt cctccaacag ttaaaaaacc taaagaaatt
    30121 ttcttttcgc ttagcggata aaaaattggt attccttgct ttgtaaataa atctcctaaa
    30181 aacatatgac ttgcataacc aatcgtacca taaaaagata aattattaat attagtgatt
    30241 aattctattt gttttagtaa aaaatatact attatagttg caaatatgct atgagaaaaa
    30301 cttctgtgct ttaaccaggg aaaaattgac aacattagac aaaaaattgt aaaatatatt
    30361 tcaacttcta tgatgtataa gcatatagct aatagtataa atattaatga tagaaaaact
    30421 tttcttagaa atgtgtgggt tagttttgcc tcaataatta taattgcaac aaatgtaatt
    30481 attgcgctta aataaaaatt atcatttata tttattgaaa taaagaaaat aataatatta
    30541 acagcatata taaaaattct atatatgtat ttggatacat tgttttttag aatgaaattt
    30601 gagaccatag aattagattt atccaaatcg ggtagtacag caaaagtagc tgaaactaaa
    30661 atatcaacta aagatatagg aattttaaat attaaagatg tttggatagc tgttaagatt
    30721 cctattgcac aatgagtttt accacgcata aatcctccta aattatccga tattaaatca
    30781 tataatattt agaggatatc aaaataaaat aggtttgtca aaataatacg ttaaatgtat
    30841 tttaaatata gcttaaaata tgatacgaat tatggtacaa taagaataac tggtagcgag
    30901 tgcgtgattt gatattattt atgattgtag aacgtgttaa aaaattaaat agacagaagg
    30961 agatgatgca attgttcaaa aagaacacca acaagataaa ggtaatggcc ttgggtggac
    31021 ttaacgaagt tggaaaaaat atgactgttg ttgagtataa agatgaaata attgttatag
    31081 atgctggact tagttttcca gaggatgaaa tgttaggagt agatatagtt ataccagata
    31141 taacttattt agtaaaaaat agggataaaa taaagggtat atttattaca catggacatg
    31201 aagaccatat aggagctctt ccatatatat taaagaaaat aaatgtacct gtatatgggg
    31261 caagacttag tataggtctt atacaagtaa aacttaaaga acataaaatg aataatgtta
    31321 agttaaatgt tataggtcct agacaagtta taaagcttga taatatggaa gtagagtttt
    31381 tgaaaaataa ccatagtata ccagatgctt actctattgc aatacacaca gaccaaggta
    31441 taatatacca cacaggagat tttaagattg acttgactcc tattgatgga gatgttatgg
    31501 atatgcatag aatctgtgag ttgagcaaaa aaggagttct tttaatgctg gcagatagta
    31561 ctaatgcaga aaaaccagga tttactatgt ctgaaaagac tgttggggta ggtcttgacg
    31621 aattatttgc aaaaggaaat ggcagaagaa ttatagttgc tacctttgca tccaacatac
    31681 acagattaca acaaataata aatactgctg aaaagtttaa tagaaaagtt gctatatcag
    31741 gtcgctcaat ggtcaatgta gttggagttg caaaagaatt aggataccta gatatttctg
    31801 atgacatgct tatagattta aatgatatat gtaagtatga agatagtgaa ttagtgataa
    31861 taacaactgg ttcacaaggt gaacctatgt cagctcttgc tagaatggct ttttcagagc
    31921 acaaaaaagt agaaataaag agtggcgatt tagttataat atctgctcat ccaataccag
    31981 gaaatgaaaa attaatatca agagtaatca atttcttatt tgaaaaagga gcagaagtag
    32041 tatacagtga tatagctgat atacacgttt ctggacatgc ctgtcaagaa gaattaaaac
    32101 ttatacatgc attagttaga ccaaagtttt ttatgccagc tcatggtgaa tatagaatgt
    32161 taaaaagaca tgctgaaata gctgaacagc ttggtatgga taaagaaaat atttttgtca
    32221 tgcaaacagg agatgtttta gaattagata aaaattctgc taaggtagca aaccgtatac
    32281 aaacaggaaa catattagtt gatggtctag gagtaggcga tgtaggtaat atagttttaa
    32341 gggatagaaa gcatttatca gaagatggtc ttatgatagt tgtagttact atttccaagg
    32401 atgagggtaa ggtcttagca ggtccagata taatttccag aggattcgta tatgtaagag
    32461 agtcagaaga tttaatggat ggagcaaagg atataattaa gaatgttcta aatgaatgtg
    32521 aagagaaaaa tattaaagaa tgggcttatt taaagaataa tattaaagaa aacctaaaag
    32581 aatatttata tcaaaaaact aaacgaaatc caatgatact tcctatcata atggaagtat
    32641 aatataaaaa aactataaat ttgaaaatta gacctcttgt aatttttaaa gtaatatcaa
    32701 aaatccaatt gatattatct taagaattac aagaggtctt tttaatactc attttaaaaa
    32761 aatatatatt acataaaata ccaattataa caatctttta ttagtaaaaa ctacttatat
    32821 ataaatttta ctgataggag gattcttatg gatgatgttt caagacaaaa tgctataaaa
    32881 gctttaaaac aaacaaaaat ggaaatagca ggagagtatg gaatgaatta tgaagatgct
    32941 tttgaaataa tagaaaatgc gtctaataaa ggtgttttag aaggttactt taaaaagctt
    33001 gaaaagaaaa aaaatttagg tcaaggtata tctaggcatt tagaataaaa aaagttaaat
    33061 gtgagaaaat aagtttaaat aaactttaag aggtgacatc gatgaaaaaa ttagctagta
    33121 ctgctttggc tatattaatt gcgcttactc ctttaagctt ttcttttgca aataataagg
    33181 aaaatgctga tgccaaccaa ctaaatatat cttcaaaatc agcaattttg atggatgttg
    33241 gtagtggaca aattttatat gaaaaggatg ctcataaaaa gcttcctcct gctagtgtaa
    33301 ctaaggtaat gactatgcta cttatagtag aagctttgga ttcaggcaag attaagcttg
    33361 atgatgaagt tcaagtaagt gaaactgcat ctagtatggg tggtagtcaa atattcctag
    33421 agccaggaga aactcaaaag gttgatacat tattaaaagg tatagctgtt gcttctgcaa
    33481 atgatgcttg tgttgctatg gctgaacact tagctggaag tgttgaagga tttgttgata
    33541 gaatgaatgc taaagcaaaa gagttaaata tgaatgatac tcattttgca aatacaaatg
    33601 gacttccagt tgcaaaccac tatacatctg ctcatgatat agctttaatg tctagagaac
    33661 tattaaaaca cgaaatgata agtaaatact taactacatg gatggataag gttgtagtag
    33721 ggaagaaaca agttacagta ggtcttgcaa atactaataa acttataaag cattatcaag
    33781 gagcaactgg tgttaaaact ggttttactc aagaagcaaa atactgttta tcagcatctg
    33841 caaagagagg taatactcat ctagttgctg caactttagg agcagagact tctccagaaa
    33901 gatttaatga tgcctctagc cttttaaatt atggatttgc taattatgaa agtgttaagt
    33961 tatgtagtaa aggtgataat atagcaacac ttacattgga taaggctgat gaaaacaaag
    34021 ttaaattggt tgctaaagaa gatttaaatg ctcttattaa aaaaggaagt tctaaagaat
    34081 ttgagaagaa aattgaaata gtaaaaaatc ctaagatgcc aattaaaaag ggaactgttt
    34141 taggaaaaat aaagatatgt aaagataaaa aagtaatagg cgaagtggaa ttgataaata
    34201 ctaaggatat aaataaggca agctatctac aaatgcttca aagaataatt gataatatga
    34261 tataaataat tatcagatga aatataatta taatacacaa agatatgatt ataatacaca
    34321 taaaaaatac ccttatgtaa ttatttgcca taggggtatt tttatttacc atatagaagt
    34381 attttataat cttatgattt ttatagaaat atagaaaagt ttatgtatct taaaatatca
    34441 tttgatttaa tatcatatat agggttgttt aacaattatc taagtaaagg catactacca
    34501 gtaagtttat tcactttctt tttattccca taaattgcta tcccaaaata ctgtaactca
    34561 tcttctggaa cactagcaat cttttgtgta aattcttcat aaagattgca actttgtgct
    34621 acatctgaaa aatctacaac agttaaatcg ttaaattcca aagtatataa ttttttacgt
    34681 aaatctttta ttatttcttt gtttcctttt aaaataggta caggaatgtc aataattcct
    34741 aagtggctat tacctgtttt gtcaattaca tctgggccaa cagtttctgg ggcatgtttt
    34801 cctagtgtaa ttcccattat agctgctgta ttggatataa ttcccattgg taaattttcg
    34861 tctattacca tgacacattt tgaattttta gtttccattt ttatttctcc tttttacctt
    34921 atttaaagtt gtttgaatca tcatttataa atatattttg atactgcttt ggtgtaagac
    34981 caataaaatt cttaaaaaag tttgtaaagt gactttggtc tacaaatcct gtttgtatcg
    35041 cagcatctat aggttctacg cctttttcta aaagcttttt agctttgttt acccgtatat
    35101 tttctaggta tctatatggt gtaatacctt ttaatttcgt aaaattacga agtagagagt
    35161 acttattcat acctgctata gtgcttaatt cgtcaagtac tatatgttca gcataattat
    35221 tttctagata atcacatact gcttgaattt ctatatttgt attttccaag ttagattgca
    35281 aatttggctc tgtatgttct tcaattaatt gttcaattag gaagaaaaaa agctcttcct
    35341 ttttaaaatc caattcttct tccatgatta tatagtgtaa ttcttgtagt agaggtacta
    35401 gctcactgcg aaatataaca ggttgattaa attttggtaa ataattttta cctgtaattt
    35461 caaagacagt ttttttcatt atttctggct taatattaat acatctgtaa tcaagtactt
    35521 tatcatctat ttgttcacaa gtatgactat caaaagggtt aaaaagtagc aaatctccag
    35581 tacttgtggt atactcttta tttttacaag ataaatatct ttgacctttt tctataaaac
    35641 caattacata atgttcatga aaatggtttg ggaatttttg cattatgcct ttaaatctat
    35701 atgcttcaat ttttaattcc ctatcaaagc atactgtgcg ttcttcttgt ctcacttagg
    35761 taacctcctt tcatgttata caaagtgtaa cacatatttt tttatacttc ttgtataata
    35821 ttgactaaga gacaataatg tcaattcatg tcaatataat attacactta cagtaggtgt
    35881 aattattata ttttcacaat gaatatgata taataataaa agttataaaa taaaaagcaa
    35941 attttaattt tatgcctaga agttaaaatt attataatgt aaaataattt tgattataag
    36001 ctatttaatt gttataataa tattaaaaat ttaatttagg agatgtacat taatgttaag
    36061 tatgaatata ggagaaatag tagcaagttt agttggtata gctatggcaa tatcaataca
    36121 tgagtttggc catgcttatt cagctcactt attgggagat gatacagcta aagcttatgg
    36181 tagaatgaca ttaaatcctg taagacatgt tgacccaata ggtcttttgg ctatgtttat
    36241 ccttaagata gggtgggcaa agccagtacc agtaaatcca aataacttta aaaactataa
    36301 gataggaaac ctgatagttt cacttgcagg cgttttttgt aatgttttga ctgctatact
    36361 gtgtgtaatt atcaataagt atgtgcatat gtatgctata aatacaatag ctgaatatgt
    36421 gtttttatat agtattggat ttgcagcttt taacttactt ccgatacctc cacttgatgg
    36481 atggggagtt atatctacat ttgtaccata taaatggaat gaatatttgt ataaatttga
    36541 aagcatgagt tatataattt tattaattgc tttatttact ggtatgtata gaataatatt
    36601 aacaccaata tatgcagtgt tgctaaaaat agtatattta tttgtttaat ataataaaca
    36661 gattaaagag ggattgatat gaagtataat atacaattac aagtctatga gggaccatta
    36721 gatttacttt atgatttaat aacaaagcat aaaatagata taaaggatat atccataata
    36781 gatataacta agcagtatct aaattatttg aaaatgctag ataaaatgga tttagagata
    36841 actagtgaat ttataactat ggcatcaaaa cttttagaga taaagtctaa atatctgctt
    36901 tataagcaaa aagatgaaga agaagaccca agaatagaac ttatggaaaa gttagaagaa
    36961 tatagaaagt ttaaggtagc atcacaagat ataaaagaaa atataactta tgttaatgag
    37021 agattttata gaaataaaga agagataatt attgatgaca atgtggattt agaagatata
    37081 tcaatagaag caataaaaaa tatacttcca tacatattta aagttaaaac atcacagata
    37141 gaaaatgcta atgatgagaa actagataaa atagtaagga agaaaataat atctgtagaa
    37201 gaaaaaatat tatatataag agatattata aaagagaaga ttgaagttac ttttacaaat
    37261 attataaaat catatgaaaa tgatgaaata atagctactt ttttatctat attagagctt
    37321 ataaaagaaa aagaaatagt cgtagtacaa gatatatttt ttgatgatat tctaataaga
    37381 aaaagttcgg agtgttaaaa tgaaaagaga agatataaag tatattatag aatctgttat
    37441 gtttgcatat ggtgaaccaa taagtataaa agaattaaac tatataataa ataaagaact
    37501 ttcatcaaaa gaaatagaga ttatgttaaa tttacttatt gaggagtaca gagaacaaaa
    37561 tagaggtatt caaataatca agttagagaa taagtaccaa atgtgtacaa ataaagacta
    37621 tgcagaatat ataaagaaga ttattgaacc aaagaaaaag aaaagtttga gccaagctac
    37681 attagaaact cttactataa ttgcctacaa acaaccaata acaaaggtag aaatagagga
    37741 tataagagga gtaaaatgtg ataaggtatt acaaactttg tttgaaaatg aacttataag
    37801 agaagctggt agattgaata agatagggaa accaataatt tataaaacaa cagatgaatt
    37861 tttaaagttg ttgaatatag aaagtcttga agaattgcca cctatagaaa attatcaaga
    37921 agtggcaaca aatgaataaa aatataaaat cacaataatt tagtatgtaa ttttaaattt
    37981 taaaagattt aaaatgctct aagttgttgt gtttttttgt ataaatataa aattataatt
    38041 ctcttaaaat aaatatggat aattaagtat aaatagtaat tttttgatga taatataaac
    38101 atggagctta atgaattatt taattttaag tatttaataa tagctgtaat ttttattata
    38161 agtgtaacta tgttgatttt aatatctcat ataaacatct taataatagc tgatataaaa
    38221 aacaaagata tttgtttaaa gcttaatata aaatacatgt ttaatttaat aaatataaat
    38281 agacaacttt atccagctga aaatagtaaa aataatgata aaaaagaggg gatgaagaat
    38341 aatatagatt caagtatatt attagctgat gaccttttga gcatttatag attattaaaa
    38401 aagataaaaa tacatgaact ttattcaaat attaattttg gaactggaaa tattggctta
    38461 acatcttctg tatatgtatt gataaatact ttgtatggaa atttatttaa tatgattgat
    38521 gcagaaaaaa tgtatttaaa tgtaaatcca gatttcacaa aagattatgt tttaggaaat
    38581 ataaggatac atataaggcc aagaataaaa gctttattta atattataat aatgattaat
    38641 aaaattatga ataaaaataa aggaaataag gaaggtgata gtaatgagag caacaggttc
    38701 gatacagagt cttatggaaa caactcttga aacaattaaa ggttctatag atgcaaatac
    38761 tattatagga gaccctataa aaacagatac tacagtggtt gtacctatat caaaggttac
    38821 aattggcttt ggtataggag gaggagaata ctcaaaagga tatgatgata aagataggga
    38881 aattgaatta aaaaatgaaa aatcagatac gaattttgct ggaggtagcg caggggctat
    38941 atctgtacaa ccagtagcat ttgtagtagt tgaaagtgga gagactagaa taatgagttt
    39001 agatagtaat atcaatctag tggataatat attatctata actcctagag tattggagaa
    39061 aattcaaaat atatcacaaa gtaataagaa tcaagataaa aacaatatgt aagaataaaa
    39121 tatttttaaa tatgtatata gttttaagta aagtagtggg gttaatataa atcccactat
    39181 tttgttgtgt actttaaaca tttatatcta ataagatttt agtttaaaac aatttaaata
    39241 gataataaag ttgatatata gtataattat aaaaagaaaa gaagtattat attatagata
    39301 tataaacgca tttgagatat aagagggagt tataaatcat tagttttgag gtgaatgtta
    39361 tgagcgataa agaattatct attttgttgt tagaaagtat gaataatttt cataatttaa
    39421 taaagattat taataacgaa agatataaaa aagataaggt tcttacagaa agacagttct
    39481 ttgccttagt aaaaataaga aaacatgata aaatagagct taaaaatcta agtagagatt
    39541 tgcatgtatc tacttctagt ctgtgtatac tacttaataa attggttgag caagagtatg
    39601 tatataggga agaagatagt agagatagac gaaatacttt ttatggaata actaaaaatg
    39661 gagaaaagat attggataat gaaatactaa agtttgtatc tataataagt gataaaatgg
    39721 attgcctaga tataaataat aaagataaat tatttacttc tttggaagag tctaaaaata
    39781 taatagaaca attattttga aaaggagaat ttattatgaa tataaagtat tctaaagaaa
    39841 tattaaaaag tttagaaaat gctataacag tagtagctct atttgaggga gaagatgttt
    39901 ctacgacatt tgataaaata aatatgataa gcagaaattt taattctaaa gaaaatagta
    39961 tagatactgt aacattggtt gaaaataaca atttggtaaa tgtttgtctt gttggttttg
    40021 gtaagagaga gttattgaat agagaaaaaa ttagaatcat aggtgggaat ttgtgtaaaa
    40081 aattaaaaaa tatattgaaa aatgaagcat ataagagtag tgatgttaat gtactgaatc
    40141 ttaatttaaa tagtgatgaa ataggttgtt ttgtagaagg gatattactt ggaaattata
    40201 agtttgataa atataagaca aaaagtaagg attttgaaag aaaagaagtt gatactataa
    40261 ctatatttac tgaaaaagaa gttgagtgtc aaatagaaaa ggctaaaata ttagctaatt
    40321 caactataat agctagaaat ctagttaatg aaccatcaaa cgtaatatat ccaaaaacat
    40381 tagcagtaga aacagttaaa cttggtgcag agtttgggtt taatgttgat gtttatgaag
    40441 aagaaaaaat aaaggcattg ggaatggatg cttttttcgc tgtttcaaga ggttcaatta
    40501 ataaaccaag attcatagta atgagatact ttggagataa agaaagtaca gatatattag
    40561 gtctagtagg taaaggattg acttatgata ctggtggata ttctttaaaa tcaaatgctt
    40621 ctatgctaga tatgaagaca gatatggctg gtgctgcgag tgttataggt gctatgtgtg
    40681 ctatatctca aagtaaatta aagaaaaatg ttatagcagt agtggcagca tgtgagaatg
    40741 ctttatcagg aggttcatac aaacctggag atataattag ttctatggca aagaaaacta
    40801 ttgaagtttt aaatacggat gcagaaggta gacttacatt agctgatgca atatactaca
    40861 ttataaacaa tgaaaaagta acaaaggtgg ttgatgtagc tacattaact ggtgctgctt
    40921 taatattgtt aggtaatgtc gcaactccta tagtaacaaa taatgatgat ttttattgtg
    40981 aattagaaaa agctgccact ttatcagggg aaagggtatg gaagatgcca atttatgatg
    41041 aatttaaaga tatgataaaa ggagaagaag cagaccttaa aaacactggt ggtaaaaatg
    41101 ctggatgtat aacagcagga gcttttattg gtgaatttgt tgggaatact ccttggatac
    41161 atatggatat agcggggaca agtacatcat caaaatcaat tggatacaaa gcaaaggggg
    41221 ctacaggaga acctgttaga acattgtact atttggcaga aatctaaaaa acaattataa
    41281 aatataattt ataaagccac gtggatattt ttgtaattta agattatcta tgtggcttta
    41341 ttttttattt aaataaatta tttactcttt ttcttttttt caagtataaa agtatctcta
    41401 ttaaataaaa gagcaggtat gtacataata ctagtaacaa aaataaacgt aaaaatagca
    41461 gttgtgctat gacttaaaaa accataatag tacctagagt tggtaaatgt gtttagtaaa
    41521 aatatgaatg aaaaataaat aaaacatata gctaagttat ctctaagtgc atatctgtta
    41581 actctaaatt ttctaacatc aaccatatat atatctgcat aaattatcaa gcacttagag
    41641 aagataaaga taaaatatat taagctagga aattcatagc ccaagttttt agaaaaaatg
    41701 agttctccaa ctgaacaaac taaactccaa gaaaaaaata tattaaaaag atgatactgc
    41761 ttaaaaatta gtatggctat acacagatat atacaaatat aattgattcc aattggtaaa
    41821 gagtttagag tactataatt acctgaagaa ataagtaata attgctctag agccataatt
    41881 attacaagta atgtacaaat tatcttctca actgtatagc tataaggtaa aatatttttg
    41941 gttagttttg gacaatagta taaaaataat ccaaatataa agagacttac aaattgttca
    42001 ctagaaaaaa gaaaaatttt aaacatataa cattctctcc tataataaat ttaatatgta
    42061 tctatataaa tatattcatt atatctcaat ttaatatata aaaaagataa taatagttag
    42121 attttttata tgaattttaa taggtaaaat atcctattgt tttgtagata tatcctaatt
    42181 atgtcaaaaa ataaaaaaat ttttatttat tagagttttt ggaaataata ataacagata
    42241 ttataattaa ttaacagttt ttgtaagtat ttgacaatag agagggtgta acaaatggga
    42301 ataatagagt cagcatcaaa attggctgag atggttcatt tattggctgt tgaaaagggg
    42361 ataactgata tagaagcatg ggatgaagct gtgaaagaat acagcaaaat ttatgaagaa
    42421 agaagaaatg aatagaatga taaaaaatga aaacttgatg ataaaaaata actttattta
    42481 aagaaattca atttttatag aagtattaaa aataatataa ataaaaagat ggtatttcaa
    42541 atgtaagtaa aaaatcattt tgggatacca tccttattat ttattttaat aatatataag
    42601 taataaatct tacttatcca tattttttat gtaacctctt ttttctaact tttttatatg
    42661 ctccttacgt atttcatcaa gattaatacc atattgttct tctagcttaa acatcatagt
    42721 aacacatgtc tgagctacat ccattagttc cttagcagtt ttctttataa tatcaacttc
    42781 atctaaatca ttattttctc cacttagatt tctgaattta cctatacatt cagctaattc
    42841 accttgttct tcacccattt tgataaatgt agattctagt gttgggtcta aattattaag
    42901 ctctggtaaa gatatagttt ttagtttcat aaaagctcct ttcaagttat tcgtatttat
    42961 actaaaacat cataacaaaa ataatactaa aaaaaaactt taaattcaac ataaaaactt
    43021 acatatataa taaaaatcgt gaaataaatc tatatttgtc ttaatacagc ctcatataaa
    43081 acttctccaa taggtttatt tattacaaga gaagctgact tatcatagac tgtatttgct
    43141 ttattaataa gagcaatata atcacctttg taataatcta taaaacttgc tgctgggtac
    43201 acagctaatg atgtacctcc tataatcaat aaatcagcat tacttatagc agaaattgtt
    43261 ttagtaatga catcactgtc aagagcttcc tcataaagta ctacatctgg ttttactata
    43321 gaaccacagt tgtcacagta aggaatatta cctcccagat ttaacataga ttctaagtca
    43381 aaaaacttac cacatttagt acaataattt ctatgtacag aaccatgaag ttctagcaca
    43441 tttttacttc cagccatttg atgaagtcca tcaatatttt gagttatgac agctttaagc
    43501 ttacccattt cttcgagttt tgctaaagct atatgagcat tattgggttt tgcattagga
    43561 tatattaatt tatccttata aaattcaaaa aattcttctg gatatctaac aaaaaaagta
    43621 tgtgaaacta attgttcagc agtaaattgt ttattgagtt tttggctaaa taatccagta
    43681 gaacttctaa agtctggaat attagattca gttgaaacac ctgctccacc aaaaaataca
    43741 atattattgt gattagctat taagtctttt aagctatttg catccatagt tacacctcca
    43801 aattattata tataaattgt actacatatt aggtcgttta tgttttatta atttaaataa
    43861 atatatagtt taataagtta aataaaggga atataaataa aatgtataca gagtataaat
    43921 agacaatatt tactaaaata acaagttgtc gtataattat attaaaattg ttttagtgta
    43981 taagaagggc gggggaagta cgtgaagaaa aaagcagctt tagcaacatt ggctatgtta
    44041 cccttaggtg tggtaaatgc acatgctgat ggagatatag gtatagtgac tataaattat
    44101 ttaaatgtaa gaaatgaacc aactgccgaa agtagcatag cctttgttgc taaaaaagat
    44161 gataaagttt tgattaaaga ctcttctaat ggatggtata aaataaaagc tgaatctgga
    44221 caagaaggtt gggcttcatc aaaatatata gcaaaatcaa atagtgactc tttaagaacg
    44281 tctacaaata aagaaaaaca agttatttca aatagtttaa atatgagaaa tggagcaggt
    44341 acaagttaca gagtaataac tgtactaaaa aaaggtcaaa aagtagaagt aatatcagag
    44401 agtaatggat ggtctaaaat caaatatgat ggaagactag gatatgtatc tagctcttat
    44461 ttaggagacg tttcaaactc aactaataaa tcaaaaacta aacaagtgaa tacaacttca
    44521 ctaaatgtaa ggagtggacc aaatacaagt tatggtttgt taggcaagtt gccaaaagga
    44581 agtaaagtag aagtaatatc agaaggtaat ggatggtcca aaataaagta taatggaaaa
    44641 gatgcctatg tatctagtat gtacttatcg gatgtaagtc aaagtaattc agacaattct
    44701 agtcaaagca atgataaaaa gaatactgat aaggtcgtaa atacagcttc tttaaatgta
    44761 agaagtggac caggttctac atatagtaag ttgggaaaag tttataaagg aagtaaagta
    44821 actgtactat cagaaagtag tggatgggct aagattaatt ttaacaataa agaagcattt
    44881 gtagtaggca attatttatc tacttcagca gatacttcaa ataataactc aaatagtaac
    44941 tctgataaca gttctaatag taatggcaat aattcttcat catcaggtca agtaaatggt
    45001 atgtcaggta taagtggggc taaaattgat tataaatctt tgagttatac tttagaatct
    45061 catataagta aacaagttga gaaagcagca tcaggaggaa atgtgatagc tccaagtaat
    45121 aggaaaagca ctccaagtcc tgaatttagt actttttcag ctcaaagaac aagctcattt
    45181 gtaaatgcaa gttcaagtga tatagaatat tatttaaatc ctaaaaattt tacaaatact
    45241 actaaaggta tgatgcagtt tttaaagatt aacagttata gagatggtat ttcagaatca
    45301 agtcttaact cgtatcttaa tggtttatct tctagtgtat ttaaaaacca gggagcagcc
    45361 tttataaatg ctgccaagaa gtataatata gatgttgtat atctagtatc tcatgctatg
    45421 tgggaaactg cttatggtaa gtctacactt gcccaaggtc aaacattaac atcttataag
    45481 ggacaacctc ttagtaagcc agttaaagta tacaattttt ttggtatagg agcaatagat
    45541 aaaagtgcta atgtttcagg tgcagaagca gcgtattcca atggctggac tagtgtagaa
    45601 gctacaatag atggctctgc aaagtggata tcacaaaatt acgtaaatag ttctaagtac
    45661 aatcagaata ctatctacaa gatgaagtgg aattatgatt atacatggca tcagtatgca
    45721 actgatgtga actgggctaa tggaatttct ggaattatgg aaaatttaat tggtctttat
    45781 ggaggaggaa gtagtttggt ttttgaagtt cctcaataca agtaatacat aaataaaaaa
    45841 tatagactat gggtagtttt cattttattt aaattatcta tagtcttttt gtatataatt
    45901 tataatctgt aaatttaatg ctaacaaaac ttttatgtta taatattaat tctaagtaaa
    45961 tataagtgag taataggtag aaatagataa aaagtggtaa taatatatat aaagataatt
    46021 ttgagaaagg aggatatata tggaaagtat taaggaatat ttggataagt tagaaattaa
    46081 taatagtggt cttggaaagc aacttaaaga agtttatata aatagagtag tttattttaa
    46141 ggaagataag atagtttatt tttatctaac ttctaaagat attgtttctc atgaactttt
    46201 agataaattt aaagaagaat tgatgtataa actcgattat tttaaagata tgaggatgaa
    46261 gataagattt actggtcttg aaagaaaatc caataaagat gttataaaaa aatattggaa
    46321 taatatattg tatatattaa agtatctttg tccatctatt gcagggtggt ataaacaagt
    46381 agaatttctt tgtttagaag aagaattaaa aataaaactt ccaaaaggta tattttatga
    46441 gcgattaatg aaaaaaaatg taacttatgt acttaaaacc gtgcttagcg aagagttggg
    46501 attagattta aatataacaa tagaaaaagc tgttgatgaa aaggtaaata aagaaagact
    46561 cataagaatc aatgatagag aaatggaaga aaaaattagg gctttagaaa ttggaaaagt
    46621 taataactgt gaagaaaatg aagaggaaag ttatgtcatt aagtctgatg tagatgaaaa
    46681 tttaatctat ggagataatg caaatgctat gattgaaaat atagttgaat taaatgcatc
    46741 ttctggaaca gttgcagttg ttggagatat atttgatgtt gacactaaag aacttaaaaa
    46801 cggaaaaata cttatgatag cttcaattac agattatact agctcaataa gctgtaaact
    46861 ttttttaaca gatacaaata aggatggagt acttgaaaat gttaaaaaag gagcatactt
    46921 aaaaatcaag ggtgacatag tttatgatac atatcaaaga gaaattagta tgatgattag
    46981 tgggataaga aaagaaacta gaatagagag agaagataaa tcagaggaaa aaagagtaga
    47041 actccatgca catacacaaa tgtcttctat ggatgctatt tgttctgtta aaaagcttgt
    47101 agagcgtgca gccaaatggg gtcattctgc tattgctata acagaccatg gtgttgtaca
    47161 aggatttcca gatgctatga atgcaggtaa gtcaaataat ataaaaatac tttatggagt
    47221 agaagggtac ttggttgaag atgattctct cattatagag gatgcaaatg ataaagaact
    47281 ttcgcagaca tttgttgtat ttgacataga gacaactggt ttttctaata caaatgataa
    47341 aataactgag attggtgctg taaaaataga aaactttaag attgtagata gatttagtga
    47401 gttaataaat cctgaaaaag atatttctta taagatacag gaattgacag gaataactaa
    47461 tgaattaatt aaagacaagc caaccattga agaagttctt cctaagttta tggaatttgt
    47521 tggagatagt gtattagtag cacataatgc agagtttgat actggattta tatcgcaaaa
    47581 atgtagggaa caaggcttgt tatataataa caaaaaagta gatacactta tgttagcaag
    47641 agtaatgttg ccaaacttaa aaagacatag attaaatgtc gttgcaaaag aacttggtat
    47701 tcctctttta aatcaccata gagcagtgga tgatgctgaa gctacagcac ttatatttaa
    47761 taagtttttg cagatgctta cagaaaaagg tgcaaaaact ctaagtgatg taaacaatat
    47821 acttggaaag attgattaca caaagcttag cacaaatcat ataaccttga tagcaaaaaa
    47881 ttctataggt ataaaaaatt tatataaaat aatttcagat gcacatgtaa atcatttttt
    47941 tagagcacca agaatcctta gaagtgtatt aaatgaatat aaagaaggat taataattgg
    48001 ttcggcttgt gaagctgggg tggtttttca agctgtaaag aaaaacgtgt ctgatgagga
    48061 aatgaaaaaa ataatagatt tatacgatta tattgaagta atgcctatag ataataatag
    48121 atttatgatt gataaaggag aagtaaagga cgaagaagag ttaagggagt tgaataggaa
    48181 attaattgat acagccaaaa aatttgacaa aattccagta gctactgggg atgttcattt
    48241 tttagacaaa catgaagctg tcttaagaaa agttcttaaa tattctcaag gttttaaagt
    48301 agatgaagaa gaaacttatt tacattttag aacaacagat gaaatgttgg aagagtttag
    48361 ttatcttgga gaagaattgg catatgaagt tgtagttgaa aatagtaatc tgattgccga
    48421 tatggttgaa gatataaaac ctataccaga tgatacttat cctccaatta tagagggctc
    48481 agatgtggag ttaagagaaa tgtgttacaa aaaagccaaa cgaatctatg gagacccaat
    48541 accagaaata gttcaaaaaa gactggatag agaattaaat tcaataataa gcaatgggta
    48601 tgcagttatg tatattatag ctcaaaaact ggttgcaaaa tctctttcag atggatattt
    48661 agttggttca agaggctcag ttggctcatc ttttgcagct actatgagtg atataacaga
    48721 agttaatcct cttccagcac attatatttg tgaaaacgaa gactgtaaat attcattctt
    48781 ttatgaaata ggtgaatggg gctcaggtgt tgatttacca gacaaggatt gtccaaagtg
    48841 tggaagaaaa cttgctaaaa acggtcatga tattccattt gaggttttct taggttttga
    48901 aggtgataaa gaaccagata tagacttaaa tttctcagga aattatcagc caacaattca
    48961 taaatacaca gaagaactat ttggagaggg gtatgtatat agggctggga ctataggtac
    49021 tgtagcagaa aaaacagctt ttggatacgc aagaaaatat gtggaagaaa ataatataag
    49081 tgtaccaaat gcagaagtac ttaggctttc aaatggatgt actggagtaa aaagaacctc
    49141 aggacaacat cctggtggag ttatggttat accagactat aaagatgtat acgattttac
    49201 acctatacag tatccagcaa atgatacttc ttgtggtgtt ataactactc actttgatta
    49261 tcattcaata agtggtagaa tacttaaact tgatatactt ggacacgacg gtcctaccat
    49321 tataaggatg cttgaagata tgactggaat aaatataaca gaaattcctt tagatgataa
    49381 agagactatg tctctattta catctacaga agcattaggt gttacaccag aagaaataaa
    49441 ctgtcctata ggttgccttg ctgtaccaga gtttggaact aagtttgtac gacaaatgtt
    49501 acttgacaca aaacctacta catttgcaga acttgtacgt atatctggtc tctctcatgg
    49561 gacagatgtt tgggtaaata atgcacaaga cttagttaga gaagatatag ttggattaaa
    49621 agatgttata tctacacgag atgacataat gaactattta atatttaaag gattacctcc
    49681 caaaatgagc tttacaataa tggagagtgt aagaaaaggt aaaggtttaa aaccagaaca
    49741 cattgaagaa atgaaaaaaa ataatgttcc agaatggtat ataggctcat gtaaaaagat
    49801 taagtacatg ttcccaaaag cacatgctgt tgcttatgta atgacatcat ttagaattgc
    49861 atattgtaaa gttcactatc cagaagcatt ttatgcgact tattttacga caaaagttga
    49921 ggattttgat gcagatttaa ttgttaaagg attagatgct ataaaatcaa aaataaatga
    49981 aattgagtca ctgggaaatg atgcaaccac aaaagaaaaa ggtatgttga ccgttttaga
    50041 agttgctctt gaaatgtatg ctagaggaat aaaattatta ccagttgata tatataaatc
    50101 agatgcaact gagtttatag ttgtaggaga aaaaacatta cttccaccaa tggcagcaat
    50161 acaaggtctt ggaggaaatg cggctataaa catccaaaat gaaagaaaaa atggtgaatt
    50221 tatatcaaaa gaagatttga gaaagagaac aaaaatatca aaaacggtaa tagaaactct
    50281 tactaatcat ggttcacttg agaatatgag tgagagaaat caattgtcat tgttttaagt
    50341 tagcccaaaa agttgcaaat aaaagaattt tatgatatca tagtatagaa aatagtatac
    50401 tttgcagaaa ctaagagtga gacagctgtt ctcactcttt tattttaaat atattattaa
    50461 aaagctggtt tatttttatt aaatatattt tatttaagat tatataaact ggtcatttac
    50521 aattgaatag gaggaacttt aatgaaaaaa aatttagaag ctacaattga ggagattgta
    50581 actaaaataa cggatgaaca tggatttgaa atggttgatg ttgaatatgt aaaagaagca
    50641 ggagaatact acttaagagt atacatagat aaagaagaag gaatatcttt aaatgaatgt
    50701 gaattagtta gtagagaatt aagtccaata ctagatgaaa aagaccctat aaaagaaaat
    50761 tactttttag aggtatcttc tccagggctt gatagagcat taaaaaaaga cagagatttt
    50821 gttagatatc aaggtagaga tgtagattta aaattatata aaccattaaa tggatgtaag
    50881 caatttgaag gtgaacttgt aggattaaca gaagataata atataaaaat cattgcaaat
    50941 ggtaaggaaa tggaatttaa tagaaaagat gttgctattg tcagattagc aataaagttt
    51001 tagtggtata ttaaataggg aggatataaa aaatgaatca tgaatttatg gaagcattag
    51061 atgaattagt agttgacaga ggtatagata aagaaatact tatagatact atagaacaag
    51121 ctcttttaac tgcatacaag aaaaactttg gttcagcaca aaatgttaga gttgaatttg
    51181 atagagacaa gggagatata aaagtatttt ctcaaagagt tgttgttgat gaatcagatt
    51241 tatatgatac tttcttagaa atagagttag cagatgctag agagataaac cctaattatg
    51301 aattaggtga tattatagaa catgaagtta cacctaaaaa ctttggaaga attgcagctc
    51361 aaacagcaaa gcaagtagtt gttcaaagaa taagggaagc tgagagagaa atagtgtata
    51421 atgaatttat agaaaaagaa aatgaaatag ttacaggaga ggttgctaga gcaaataaaa
    51481 atgttgttta tgtaaatctt ggaagaatag aaggtataat gactcaaagt gaacaaatac
    51541 catttgagaa ttataaagca ggtcaaaaaa taaaattcta tatacttgaa gttaaaaaga
    51601 ctaacaaagg acctcaaata gttgtatcaa gaagtcatcc gggtctagta aagagattgt
    51661 ttgaagaaga agttcctgaa atatatgaag gaatagttca aataaaatct gtagcaagag
    51721 aagcagggtc aagaactaaa atggcagtaa gatctataga tgaaaaaata gacccaattg
    51781 gagcttgtgt tggaccaaaa ggacttagag taaaaaatat agtggatgaa cttggcgatg
    51841 agaaaataga tataataaaa tatagtgaag acccagcaga gtttatatca gcagcactta
    51901 gcccatcaaa ggttgttaga gtagatatag atgaagatga aaagtctgcc ttagtaatcg
    51961 ttccagatta tcagttatcg cttgctatag gtaaagaagg tcaaaatgca agactagcag
    52021 caaaattgac taactggaaa atagatatta agagcgaatc tcaagcagaa caagaaatgt
    52081 taaatcttga aaattccaaa gaaatagaag ctgaggatgt tgaagctgaa tttatcgacc
    52141 aagaagagtt agatacttca gaggataatt ttagtgaaga agagtaagga gggatgattt
    52201 tgaaaaaagt aaaaaaagtg cctcaaagaa aatgcatagc atgtcaagat agagactcta
    52261 aaaaagagct tataagaata gttaaaaata aagaaggaaa aatattttta gacccaacag
    52321 gaagagccaa tggaagagga gcatatgtat gtaaaagctc tgaatgtcta aaaaaagcta
    52381 taaagagtaa agcattaaat aaagctttta aaatagatgt tcctgatgaa gtctatgata
    52441 atctacttat ggagttagaa gaatatgaaa aataataaag aaaaagtact ttcgttctta
    52501 gggctcgcaa ctcgtgcagg gaaaatagtg tctggtgatg attcaacttt gcttgacctt
    52561 aaaaaaggaa aagtaaattt gattttaatc gcagaagatg catcaaataa tactaaaaaa
    52621 ctttttaaag ataaatcaac ttttagaaat attccatatc tatttttttc aacaaaagag
    52681 gaaataggat ttgcaatagg aaaatctcca agagcagttg taggaataaa agatgaaaat
    52741 ttttctaaaa agataattga actaatagaa atttaaaata aaataggggg tgatcttgtg
    52801 tcaaaaacaa gagtatacca aatagcagaa gaattaaata tatcaaatga agagcttata
    52861 aataagttag ctgaattaga tataaatgta actgacaaag attcagtatt agaaggtgaa
    52921 gagttagaat tagcacttga aatgttaggt gaagatttat ctcaagaaaa tggaaatgtt
    52981 atagaaatag atggaaagtt gacagtacaa gtattagcaa cgaaattaga taaatctcca
    53041 tcagaaataa ttatgaagct tatgaaaatg ggaactatgg caacaataaa tcaagagata
    53101 agttttgaga ttgctgcttt ggctgccaaa gactatggat ttgaattaac agtagctgaa
    53161 agtgatgata cagaagcttt agaaatagaa gctttaatgg aaattgaaga agataaagaa
    53221 gaggatttaa aacctagacc accagttgtt acagttatgg gacatgttga ccatggtaag
    53281 acatctttac tagatgcaat aagaaaaact gatgtgattt caggtgaagc tggaggaata
    53341 actcagcata taggtgcttc agaagttaaa atcaatggac acaaaatagt atttttagat
    53401 actccaggac atgaggcttt cacatcaatg agagcaagag gagcacaagt tacagatata
    53461 gcaatattag tagttgcagc agatgatggt ataatgcctc aaacagttga agctataaac
    53521 catgctaaag cagcaggtgt acctttaata gttgctatta ataaaataga taaaccaggt
    53581 gcaaacccag ataaggttaa acaggaatta gcagaccaag gattattagt tgaagactgg
    53641 ggtggagaag taatagcagt tccagtatca gctaagaaaa aagaaggaat agatacactt
    53701 ttagaaatgg tattattggt tgctgaaatg gaagagttaa gagctaatcc aaataaaaga
    53761 gcagtaggaa ctgttataga agctgagctt gataaaggaa gagggccagt tgcaacagta
    53821 cttgttcaag gtggtacttt aacagtaggt gacccaatcg ttgcaggtgt tgcatgtggt
    53881 aaagttagag caatgataaa tgcaaaaggt aagagagtaa aaacagcagg accatctaca
    53941 gcagtcgaga tattaggtct atcagaagtt ccacaaggag gagaccaatt tgtcgaagtt
    54001 ccaactgata agattgctag aagtgtagca gcaagaagac aacaaatagt tagagatgaa
    54061 atgttaaaat caactcaaag attatcacta gatgctctat ttagtcaaat gagtgaaggt
    54121 tctataaaag accttaatat agttataaaa gcagatgtac aaggttcagt acaggcagtt
    54181 aaacaatctt tagaaaaatt atcaaatgaa gaagttcaag ttaaagtaat acatggtggt
    54241 gttggagctg taacagaatc agacatatta cttgcagcag cttctaacgc aataataata
    54301 ggattcaatg taagaccagt tccaggtgca gaatctctag gagaaaaaga aaatgttgat
    54361 ataagaacat atactataat atacaaggca atagaagata tacaagcggc tatgactggt
    54421 atgttagacc ctgaatatgt tgatgaagaa acaggaaaag ctgaaataag agaaatatat
    54481 aaaatatctg gtgttggaac agtagctgga tgttatgtga ctaatggtaa gatatttaga
    54541 aattgtaaag taagattagt tagagatagc ataataatac atgaaggtga gcttgcagca
    54601 cttaagagat ttaaagatga tgtaaaagaa gttaattctg gatacgaatg tggtatgagt
    54661 tttgtaaatt ataacgacat aaaagaaggc gatatagtag aagcttatat aactaaagaa
    54721 gtagaaagaa aattataaat tcgtatcaaa gaaaatcagt tagtaaagaa ggtcgatggt
    54781 atggcatcat ataatagaac aagaaggata gcagaagaaa taagaaaagt cgtaagcact
    54841 atgcttataa atggagtaaa agaccctaga ataacatcta tggtgagtgt aactgatgta
    54901 gaagttacaa atgacctaag atatgcttat gtatatgtaa gcattctagg tggagatgaa
    54961 gaatccacac taacaggtct taaaagtgct ggaggatata taagaagaga agtaggaaaa
    55021 aatataaaac ttagatatat tcctgaaata gtatttaaac ttgatgattc aatagaaaaa
    55081 ggaatgtata tggatagcct tataaaaaga gttaatgaaa aaaatgctca acaaaatgag
    55141 gatgaaaatt atgatgaata atatggatag tattataaac tatatttatg agggtgacta
    55201 ttttatagtt acctctcata tcagtccaga tggagacaat attggttcta cactttcaat
    55261 gtattataca ttgaagaatt taggaaaaaa tgtatattat gtacttgatg atgaagctcc
    55321 attaaattta aggtttttgg ttgaagatgt aaaaatctat aagtctaatg aatttaatat
    55381 gaagaactat tctctaattg cacttgattg tggggataag atgagaatat gtgtgagtga
    55441 tgaaatcaaa aataatgcat caaaattaat ctgtattgac catcatgcta gtaatgattc
    55501 atatggagat ttaaattatg tagatattga tgcatcttct acatgtgaat tagtttataa
    55561 tttattagtt agatttcagc aaataaaaga tattaatatt ataaatgaag atatagcaac
    55621 atgtttatat acaggtcttg taactgatac tggaaacttt tcgtattcaa atgtacatgc
    55681 aagtagcttt gaaatggcaa aaaatttact tgttttaggt gcacaaaaaa atactataat
    55741 acaaaatata tatcaaagca attcttctgg ttattacaaa ttattaggag aagctctaaa
    55801 gggtttggag atatttgatt caaaggtatc tagtatagtt ttaactcaag acatgatgaa
    55861 tagaaataat attagcttta atgatgttga tggaataaca acatatacaa gagacataaa
    55921 aggtatagaa gttggaattt tatttaaaga gaaaaaacaa aatgaaatta aagtgagttt
    55981 taggtcaaaa aattatgttg atgtaagtga aatagccaag ttatttggtg gtggtggtca
    56041 tgtaagggct gctggatgta ctattagaga tagtattgat aatgcaaaga aaatggtact
    56101 agaggcagtg ttaaaatcaa tttaaggtga cagtaaaatg aataagatta taagtatatt
    56161 gaaacccaca ggtatgacat ctcatgatgt tgtaagtaga gtgagaaaga ttttaaatat
    56221 aaaaaaagtt ggtcatacag gtactcttga cccagatgct tcaggtgttt taccaatctg
    56281 tatagggaaa gctacaaaag tatgtgaagt tattttaaac aaagataaat cgtatatatg
    56341 tgagcttact ttaggtataa gtacagatac ttatgatgct tcaggtgaaa ttttaaaaaa
    56401 agttgatgat tttaaattta gtaatgaaga catagaaaga gcttttgaca cacaaagagg
    56461 agagataaat caacttcctc caatttattc agctttaaag gtaaatggaa agagaatgtg
    56521 tgatttagta agaagtggta gacaatctga aattacttta aaaacaagaa gagtaaatat
    56581 aaaagacata aaaatactaa gtataaaagg taataaagta atgttttatg ttgagtgttc
    56641 taaagggact tatgtgagaa gtatttgcca tgatatagga gaatatctag gttgtggagc
    56701 tcatatgtcg tttttgaata gaacatcttc tggtaaattt gacttagata attcaataac
    56761 attagaagaa ttagaattat tttatgaaaa taaaacttta gacaaatact tatatgatat
    56821 agattatgtc cttgattcgt ttaattatgt tgtattaaac cctaatgcta taaaatatta
    56881 tagtaatggt ggctcaatag atgataaaag gtttttaaag aataatttcg ataaagatga
    56941 tgaatttgta agagtataca gtacagataa tttcttagga ttaggaaagt tatcaaaaca
    57001 caataataca ataagtgtta aaagtgataa gatgttcata taaccaatgt atttaaaaaa
    57061 acaacaaaag agatagtact ataataactt ctatagtcta tctcttttac ttatgctata
    57121 atagtttgtg aataagttaa gagtaaatta tattttagcg gggaacattt attatggtga
    57181 ttataaaatc tataaaagaa atagcaaaca taaaagaaag tgtcattacc ataggaaatt
    57241 ttgatggtgt acacaaagga catcaagttc ttataggaaa aacagttgaa catgcaaaaa
    57301 aagaaaatat acagagtatt gtatttacat ttgcaaatca tcctgtaaat tactttagac
    57361 caaactcaac aaaaaatatt ataagcaatg atgataaaat aaaattatta gaagatttgg
    57421 gaatagatat agttgtaatc ataccatttg atgagtatat gactaaaata cctgcaaagg
    57481 atttcgtaga tgagatacta gtaaaaaaat taaaagctaa aaagatagta attggacatg
    57541 actttacatt tgcaagggca aaagaaggca atgttaatct attaaaaagc ttagaacatg
    57601 aatttggttt tgaggtagaa gtaataaaac ccatcaaaat caatgatgta agagtgagta
    57661 gtacttatat tagaagttta gtatcccagg gtgatatggc taatgtcaag gaatatttgg
    57721 gtagaaatta caagttagaa ggttgtgtta tacattctaa acaccttgga agaactatag
    57781 gattcccaac ggcaaatatt gaccttaaga ataatatgct cgttccaaag agaggtattt
    57841 atgcttctat tgtacatatt ggagatgaga cttattttgg tgctacaaat gtaggctata
    57901 acccaacagt taatggaaaa actttgtcta ttgaaacaaa tattttagag tttgatagag
    57961 atatttatgg ggaaaatata attgttgaat ttttggaaag aataagagat gaaagaaagt
    58021 ttaattcaat agatgactta aaaaatcaat tgtataatga tacaaattat gtgtatgaaa
    58081 actatgtttg caaaaacaag taatgtatga taaaatgatt aaggaaaata accattactc
    58141 ggcatttgaa tactccaatc aatgcttagt aataggcgtt tctaaaaaaa tacggaggta
    58201 atctaaatga taaacaaatc agaaataata aaagaatatg gaagagctga aggggatact
    58261 ggttctccag aagtacaaat agctttatta acagctagaa taaacgagtt aaatggacat
    58321 ttaaaaactc ataagaaaga ccaccattca agaagaggac tattaaaaat ggttggtaga
    58381 agaagaaact tattagctta cttaaaggaa aaagatcttg aaggatatag agcattaata
    58441 gctaaattag gattaagaaa gtaatttcat tctttataaa aaagcaggta tagtgtatac
    58501 ctgctttttt atagttaatt cattataaag taaaatagtt aataataaaa gtagtttata
    58561 tgttataaaa aattataaaa tgaataatat tgggtaagaa tattaaaata gtatacaaat
    58621 acataatcaa tttaaaagga aagacaggat aaatatagaa attttataac aggataatta
    58681 gttggaataa ggaggatatt attttgaaaa taaagttagt atgcgatagt ttgtgcgata
    58741 ttccagatga aatatcggaa aaagattata tagagatagt tccacttaca gttattttta
    58801 atgataggga atatatagaa ggagtagata taaagaaaga agagttttat aaaaaagtaa
    58861 aagaaatcaa gcaaatacct aaaacttcac aagctacata tatggagttt aaagaagtgt
    58921 ttgataagtt cataacagaa ggttatcata taatctgtat gacaggggct gcaaacgcat
    58981 caggaacttt tcaaagtgct atgatagcta aaaatgatgt aaatgaaaat gaaaaaatac
    59041 atatatttga tactagaaat ttatctctag gtagtggaca atatgttata aaggcatgtg
    59101 aacttcttga agaaggactg ggatttgaag aaattataga tgaattagaa aatactcgca
    59161 gtagtgtaag attgcttttt gcaccatata cacttgattt tttaaagcag agtggaagag
    59221 ttccagttgc aactgctttg ataggaaata tgttaaatat aaagcctata tttttctttg
    59281 ataatgggga agctaagttg gtaaataagg ttagaggaat aaagaatata gcaagtaaat
    59341 tggtcgatat aattttagaa atgaatgaag ggtctttaga aggaaaaatc gtcacaatag
    59401 gttgtggaga taatttacac gattgtgaaa tattaaaaga tgaagtaaat aaaagaataa
    59461 aagcaagaag agtattattt actcgaggag gagtttctat ttgctctcat acaggaccag
    59521 atatattggc tataagttgt tctaattagt agtaatataa ggtttttgca tatatatgtg
    59581 aagataattt tatattgtta atttatagta tttttgataa tatagtaaat agagtgatat
    59641 acgtgttttt taataagagg aggacaagca ttaatgtttg aacataaaat atttaaaatg
    59701 gattttgcag gaagagaact ttctgtagaa ataggaaaga tttgtgaaat ggctagtggt
    59761 agttgtatag ttcgatacag tgatagtatg gtaatggtaa atacaactaa atcagccaaa
    59821 cctagagacg gaatagactt ttttccttta agtgtggatt atgaagaaaa attatactct
    59881 gtaggtaaga tacctggagg ttttttaaag agagaaggca agccttcaga gaaagctata
    59941 cttacatcaa gattgataga tagaccaata agacctttat tcccaaaagg atttagaaat
    60001 gatgttcagg tagttgcaac agttctatca gtagaccaag attgtacacc agatatagta
    60061 gcaatgatag gttcttcaat agccctttct atatcagaca taccatttaa tggaccaaca
    60121 ggttcagtat gtgttggcct tgtagatggt gcatttgttg taaatccaaa cgcagagcaa
    60181 agagaaaaaa gttcaatgca tctagttgtt tcaggtacaa aggaagcaat aatgatggtt
    60241 gaagccggag ctgatgaagt tccagatgag gtaatgcttg atgctatttt atttgctcac
    60301 caagaaataa aaaaaatagt tgagtttata gaaggtatag ttgcagaagt tggaaaagaa
    60361 aaaatgcctg ttgaattata ccatgcagga gaagaaataa ctcaattggt tcgcgaattt
    60421 gcaactgata agatgaaaaa agcagttcag acttttgaaa agttagagag aatggaaaat
    60481 atggatagag ttaaagaaga aactttagct cactttgaag aaactttaga agattttgaa
    60541 gattttgttg gagatataga agaagtatta caagatataa taaaagaaga agtaagaaaa
    60601 cttatagtac atgaaaatgt aagaccagat aatagaaaac ttgaagaaat aagacctata
    60661 tggtgtgaaa ctggcatgat acctagagct catggttcag ccatatttac tagaggacaa
    60721 actcaagtac ttaatgttgc tactttaggt gctttaggag atgttcaaaa actagatggg
    60781 ttagatgaag aagaaaacaa gagatatatg catcattata atttccctgc atatagtgtt
    60841 ggagaagcta gaccatcaag aggtccagga agaagagaaa taggacatgg tgctttagca
    60901 gaaagagctt tattaccagt aataccatct caagaagaat ttccttatgc tattagatta
    60961 gtttctgaag tattaagttc aaatggttct acatctcaag caagtgtatg tggttcaaca
    61021 ttatctttac ttgatgcagg tgtacctata aaagatatgg ttgcaggtat agcaatggga
    61081 cttataaagc atgatggtaa ggttgcagtg ctttcagata tacaaggtat ggaagaccat
    61141 ttaggcgata tggactttaa agtagctgga acagagtatg gtataacagc aatacaaatg
    61201 gatataaaaa ttgatggtat agataaagaa attctacaac gtgctttaaa acaagctaaa
    61261 gagggtagaa tccatatact aggagagatg agaaaaacta tatctcagcc aaaaccagaa
    61321 ctttcaccat atgcacctaa gattgttaaa atgcaaataa atcctgacaa gataaaagat
    61381 gtaataggac ctggtggaaa gataataact aagataatag acgaaactgg agttaagata
    61441 gatattgaac aaactgggga agtatttata tcaggtattg agattgatat gattaagaaa
    61501 gctcaagaac ttataaataa tatagtagtt gaaccagaag taggaaaaac ttataaaggt
    61561 aaggtaagta gaataatgaa ctttggagca tttgttgaga tacttccagg aaaagaagga
    61621 ttacttcata tatctcatat agctcatgaa agagttgcca aagttgaaga tgtattgaat
    61681 ataggggatg aagttgaagt taaagttaca gagattgatg aaaaaggaag agttaattta
    61741 tcaagaaaag ttcttttacc aaaaccagaa cataaaaata aataacttat tatataatta
    61801 aaagcaaagt cttaggattt tgctttttta aatacaaaaa agtagataat tttaaaatga
    61861 tagttatgga tggcttatag ttctttttct gtcagtcttt actcttataa agaagctatt
    61921 taaaagctga ttaatagaaa gctttattga tatatataga atcacttaag ttatatttag
    61981 tgcataaaca gagcttattt ttaatagtat taaataagaa acaatttgta cataattagg
    62041 gggagtttta atgataatga tggtacttaa taagagtaag ctcaaaaaaa tcataatact
    62101 aattttagta gtgttattag tattatcagg aggggtaatg gtattaaagt tatttaacaa
    62161 caagccagta tttaatttat ttaatggtgt agatttacca tatgaaagag gtacaaagga
    62221 taaaagtgga tatgttgcat taacctgtaa tatagacctt ggatgggaaa cagagtacgt
    62281 agaatccatt ttagaaacac ttaaaaaaga aaatgtaaag attacattta atgtaactgg
    62341 aaaatgggca gaaaagaata aggatgaatt attaaagata aaaaaacaag gacatgaaat
    62401 aggtaatcat ggatataaac atttagatta ttctacatta tcatatgaag acaattatga
    62461 gcaaatagag acctctaaaa agataattga agaaattata ggtgaaaaaa ctaaattttt
    62521 tcaagcacca gcaggttcct ttggtccaga aacagtaaag gctgctaaag cattagggta
    62581 tacttctatc aaatgggatg ccgatactat agattggaaa tacaaagacc aaccagaggt
    62641 aatcattgat agaatgaaga aaaaagacat taaagatagt agtataatct taatgcatcc
    62701 aaccaacgca acgacaaaat gtatagatga tattatagct attgtaagag aaaaaggact
    62761 aaaagcagga aaacttagtg atgtatttaa gtagacaaag tataaatatt tggttaagat
    62821 tgtataagtt gtagttgaat taattaaaag actgacttat aatgtaatac atataaaaaa
    62881 taaatataat taaaacatag tgttttcaat aatccaatat gaaacaaaga ataaattgtt
    62941 aggagaatgt aatgtataag acaaaaatac tggaaaatgg gcttacaata attggtgaag
    63001 aaataccata tctaaagtca ataacattag gtatttggat aaatgcaggc tctaggatag
    63061 aagaagcaca ggtgagtgga acttctcatt ttatagagca tatgatgttt aaaggaacca
    63121 aaaacagaac atcaaaagag attgctagtt caatagataa tttgggtggt caaataaatg
    63181 catttacaag taaagaatgt acatgttatt atgtaaaact aatagatgag catatagata
    63241 caggaattga tgtattgagt gatatgatac taaattctaa atttgataaa aatgatatag
    63301 ataaggaaag acttataata ttggaagaac ttaagatgta tgaagactct ccagatgact
    63361 tatcttatga tttattagtg gaaaatatat atgctaatga tggattagga atgaatataa
    63421 ttgggacaaa agaatctcta tacaatataa ctagagaatc catgttagaa tacttaaata
    63481 agtattatat tccaaataac gctgttattt ctatagctgg aaactttaac tttgatgata
    63541 tggtggagaa aatcaaatca aaatttggac actgggaaaa gaaaaatttg agtatagaca
    63601 taagtgaggc taagtttaat ccttgcttta tatcaaaaaa taaagatact gaacaggtga
    63661 acttagctat gtgcctaaaa ggtattcctt ttgaaaatga tgaagaagtc tattcaatgg
    63721 cagtggtaaa taatattttc ggtggaagta taagctcaag gctttttcag aaaataaggg
    63781 aagaaaaagg tttagtatat tcaatatact catcacagac attatatagg aaatgtggtg
    63841 aattaggtat atttgcaagc atgagtacag aaaatttaca agatgtatat aatttaataa
    63901 agaaagaaat tgaaaatata agagaaaact atcttacaga aaaagaaata tctgaaagca
    63961 aggaacagtt aaaaggaaat tatatattgg atttagaaag tactagcagt agaatgatgt
    64021 ctactggtaa atctatgtta cttagtaaaa aagtaaaaac tacagatgaa atacttgaat
    64081 gtataaatag tgttaatatt aattcaataa agaaggttgt tgataaggta ttcaatatcg
    64141 aaaatattgg tacatgtata gttggaagag atgtagaaaa gattctacac ttggattaat
    64201 attgaaaaaa gtaaatctct ggaggtataa aatatgaatt tatctgaaat agcaggtaag
    64261 gaaatagtta acttggtcac aggagaaaga ttgggggtca ttggagaatg tgaccttata
    64321 ctagatgaaa ctacaggcgg tatattagcg cttctaattc caaaagaaaa aggatttttt
    64381 gccagaagaa aagataagtc atttttagaa gtaccatgga gaaatgtaaa aaaaataggt
    64441 aatgacatga taattataga atatgaggga tatatttagg aggaaaaaat gagtatttta
    64501 gtgcaaaagt ttggtgggac atcagtagaa tcatatgaaa aaatgaatga agtatgtaag
    64561 atagtaaaag catacaaaaa aaatgatgaa gaattacaat tagtattagt agtttcagca
    64621 atgggaagaa aaggagctcc atatgctaca gatacactta taaatttgtg tagtgcagta
    64681 aatgatgagc caagtaaaag agaacttgat ttaataatgt cttgtggaga aataatatca
    64741 ggaacaattc ttgctaattt attgaatgca caggggatag attctgtttt ctttactggt
    64801 cagcaagcag gtataattac aagtgatgaa tattctaatg caaagataaa gtatataaat
    64861 cctaaaaagg taaaaagagc tttagatgat ggtaaggttg tagttatagc tgggttccag
    64921 ggtgtaacag atgatggaga aataactact cttggaagag gcggaagcga tacatcagca
    64981 gttgctattg gtaaagcttt agaatgtgaa acagttgaaa tttacactga tgtggatggt
    65041 ataatgactg cagaccctag agtagaacca aacgctaaag tattgagttt tatagactat
    65101 gaggaagtat tccaaatggc tgacaaaggt gcaaaagtaa tacatccaag agcagtacag
    65161 ttggctaaaa gtggaaatat aactttagcc ataaagaata caatgaatcc aacttttgaa
    65221 ggtacaaaaa taggttcttt atgtagacac ttagaagaca atatagaata tgaacaagaa
    65281 agagatttta aggttgctgt tgcaaataaa gatagcgtag cacaagttaa gattaagtca
    65341 gcagaagaag tgtttacaga agtattaaat gagatagaaa agaaacttat aactatagat
    65401 atgataaatt tctttatatc agaaaaagca tttgttgtag aagatgctga tataaaatca
    65461 ttaaaggaaa tactagataa atttgaatta gattatgaag taaatagaga ctgtgctaag
    65521 gtaacattga tatgttcaag aattgctgat gaaatgtctg gtatcatgtc aaaggtagtt
    65581 agaggattat caaaagcagg ggtatccctt ttacaaacat cagactcaaa tatgactata
    65641 tcttgtttag ttagtgaaga agatatgcat acagcagtac atgctataca tcaacaattt
    65701 tatttaaaat aaactgtata atacaattat tttttaatca aatttaagaa tttcatatat
    65761 atcttaatat atttgattta tttggtaaaa ctaaattaaa tataattttg ataggagttt
    65821 ttttatgaaa gattatagag aagataatga aagatttgat aaagataatt gtagtgaaga
    65881 atctagttgc gaagagagag aatgtataaa gcaatttggt accaatgaaa tgccacctca
    65941 acctcctaaa gatattcaat gtataactat aattggagaa attgagggac attttatagg
    66001 aaatcctcaa aaaaaagcta caaagtacga gcatataatt ccaatgctat actcaattga
    66061 ggaaagtaat gatgttaaag gagtgttagt tgttttaaac actgttggag gagatattga
    66121 agcaggttta gctattgcag aacttttaaa cagtacatct aaaaaagtag ttactcttgt
    66181 tctaggagga agtcatagta taggtgttcc tcttgctaca gcaggagatt actcatttat
    66241 agcaccaaca gcaaccatga ttatacatcc agtgcgaact actggtcttg tgattgggat
    66301 aaatgagact tttgagtatt ttaaaaagat gcaagataga ataattcaat ttataataag
    66361 aacatcaaat atcaaaaaag atgtacttga aaaacttatg catgaaaaag atgaacttgt
    66421 aagtgatgtt ggtagtgtat taataggaaa agaagctgtg gattatggtc ttatagatga
    66481 agttggagga ctaaaagaag cacttaaaaa attaagagag cttataaaag aatctgagga
    66541 agaaaaaaat aatgattaaa atttgtttaa ataataaaat ttatgatata atgatgtaat
    66601 aaagtaggag tgttagtgtt aaggcattag cactttttgc tgtgaagggg taaaacttgc
    66661 taaaaataag gagtgatatt aatggccacg aaaaagaaga aaaaaaagaa ggtaaatacc
    66721 ttaagtttta atgcagaata tcataattta ataacaatat ttataggtgt atttttatta
    66781 tatagtttaa attctaattc tatgggatgg atacctgtgt taatgcaaaa tctttttaag
    66841 ggactatttg gagggctttc aatagcaata ccatttatag taattataac aggactttta
    66901 ggattttttg atggaaatga atatatatat aggctaagaa agactaaact atactacata
    66961 attattttat ttatatttgt attttatgga ttattaaatg caggaactct tcctgtagat
    67021 agcccactaa aaggtaacat gtttgatgat gttatgaaat tgggtgtaag tggacaaggt
    67081 agtggtttga tagcaacaac tattgcgtat tatatgagta aaatatttgg tatagcaggt
    67141 ggatggttaa taagtatctt cgcacttata ctttctgtaa tgtttatatt taatatttct
    67201 ataaaagatt tggtgtcaaa tgcaaaatca aaatctaaag catctaaaga cagcaattta
    67261 acgtttaaag ataaaattgc aaatatgaaa aaatctgcaa tagatatgat gactgatgaa
    67321 gtagatgata ctactataaa taaaaaacca ggtttcttta aagggttaat gtcaaaaggt
    67381 cttaataatg atgatgaaga agatgaatat tttgaagaag aaaatagtga tggtgtagat
    67441 gataaaacta taaaaatagt tggatttaat aaggcagaag atgagtattt agaaatatta
    67501 gaaggaactc aaagtatgcc agagttagat gttttaaaag aattacaaaa agctaccaat
    67561 gaaaatccag ttgtagatac taaaccagaa aaaaaagttg atatagctaa acctaattta
    67621 aatatagaaa aaactcaacc tatgagtatt gtagcagagc cagttaatga ggattattca
    67681 aactataaaa agcctagcat tgagctttta aataaagtaa ataagaagtc tgatgaaaat
    67741 ggtaaaaaga aagtgttgaa aaatgcttct cttttagaaa agacactatc agattttgga
    67801 gtggaagcaa aaattaatca agttacagtt ggacctacta taacaagata tgaaatacaa
    67861 ccaagtccag gagtcaaggt aagtaaaatt gtaaatttaa ctgatgatat agctttaagt
    67921 ttagcagcta aaagtataag aattgaagcc ccaattcctg gtaaaagtgc aattggaata
    67981 gaagttccaa atgaagaagc tcaaatggtt ggtgtgagag aagttctaga aagtgaagaa
    68041 tttaataatt ttaactctcc tcttgcaatg ggacttggaa aagacgtagc aggaaaaatt
    68101 ataattggag atataggtaa gatgccacac ttactaatag ctggttctac aggttcagga
    68161 aagagtgtgt gtgtaaatac attaataagt agtattttat ataaggcaaa tcctgatgaa
    68221 gtaaaattac tattaataga cccaaaagta gttgaacttg caaattataa tggaatacca
    68281 catctattga taccagtagt tactgaccct aaaaaagctg caaatgcttt aaattgggca
    68341 gttacagaga tgaatagaag gtacaaatta tttgcagatg ctcaagtaaa agatgtaaca
    68401 agttataatg agaaagcgga agaaaaactt cctaaaatag taataataat agatgagtta
    68461 gcagatttaa tgatggcaag tgcaaatgat gtagaagatt atatttgtag attagctcaa
    68521 atggcaagag ctgctggaat gcacttgatt gtagcaactc aaagaccatc tgttgacgtt
    68581 ataacagggg taataaaggc taatatacca tctagaatag catttgcagt atcatctcaa
    68641 actgattcaa gaacaatcct tgatatgggt ggtgcagaga agcttctagg taaaggtgat
    68701 atgttattct atccacttgg tgcagcaaaa ccagttagac ttcaaggggc attcatatca
    68761 gagagtgagt cggaaaaagt aatcgatttt gtaaaaagtc aagttaaaga tggaataaaa
    68821 tatgaagaag atataattga aactatatct aaggttaata cttcaaaggg tagtgatgag
    68881 gatgagtttt tgagtgaagc gatagaattt gtcgtggaaa gtggtcaagc atctgcctct
    68941 atgctacaga gaagatttaa aataggattc aatagagcag ctagacttat agattctatg
    69001 gaagaaagag gaataattgg agcaagtgag ggaagtaaac cgagaaaggt attaataagc
    69061 aaacaggatt tgcagaattt agaaggtgaa tagaattgtc agttataaaa atagaaaaag
    69121 cacttaagct agataaagta atatttgtag atgtgagaac tgaaggagaa tatgaagaag
    69181 accatatatt gaatgcaatc aatatgcctc tttttaaaaa taatgaacat aatgacgttg
    69241 gaacaattta taagatgcag ggaaaacatg aagcaataca aaaagggttt gactatgtat
    69301 cgtataaatt aaaggatata tatttacaag cagcagaact tgcattaaat tatgataata
    69361 ttgtcatata ttgtgcaaga ggcggaatga gaagtggcag tatagtaaat ttattatcat
    69421 cattaggtgt aaatgtatat caacttgaag gtggatataa ggcttataga aattttgtat
    69481 tagagtatct aaggcatgta atggatacaa aaaactttgt atctgttcat ggattgactg
    69541 gtacaggaaa gactgatttg ttacatttat tagatgaaaa aggaatagat gtactggatt
    69601 tagaaggcat agctaaaaac agtggttcta cctttggttt tataactttt gataaaaagc
    69661 caccttctca aaagaacttt gaaacaaaac tatttgaaag tatatttttt tcgaaagaga
    69721 attatatatt tgtcgagagt gaaagcaaac gagttggaag tgttacagtt ccaaatgaaa
    69781 ttttcgaggc aatgacacga gaaggacatc atatattatt agaatgtgat attgaaaata
    69841 gagttgatag actttgtaga gattatattt atgataaaga tgaaggtaat atattgattt
    69901 taaaagaatg tataaacaag tttagaaaaa gattgggtaa taaagtagta gatgattata
    69961 ttgatttatt agaatcaggt gaatataaag aacttgtaaa aagatatctt ttagaatact
    70021 acgacccact ttatatgcat tcagtagaaa aatataagta tagtaagatt ataaatttta
    70081 atgatacaca aaaagcttta gaagatgtta tagacttata tgagagtata ttggaaggag
    70141 aaagtgaatg ttaaaaatag cattagaatc attaggatgc tcaaaaaatt tagtagatgc
    70201 agaaataatg atgggaattt taaataacaa aggctataaa ttaattggag attttgaaga
    70261 agctgatgta attatagtaa atacatgtgg atttatagag tcagctaaac aagaatctat
    70321 agatacgata ataaactttg cagagttaaa aaaaactggc aatttaaagt tgttgatagt
    70381 aacagggtgt ctagcccaaa gatattctga agaattaaaa actgaaattc ctgaaataga
    70441 tgctatagta ggaacaggaa gctatcaaaa tatagataaa atacttaaag aattaagtga
    70501 aatgcataaa attgtaagcc ttaatgatat agagtttgta tttaatgaag atttaccaag
    70561 atatatatct acacctagct atatggccta tttaaaaatt ggagaaggat gttccaataa
    70621 ttgtacttat tgtataatac caaaactaag aggtaaatat agaagtagaa aatttgaaga
    70681 tataattaaa gaagctaaga aattagctga atctggagta aaagaacttg tggttatagc
    70741 acaggatacg acaaagtacg gttttgattt atatggaaaa gaaagattat cagaactttt
    70801 agaagaactt gcaaaaatag atggatttaa gtggataagg gttatgtatt catatccaga
    70861 atctataaca gaagaattga tacaagttat aaagaaatat gataatatat gtagttactt
    70921 tgatatgcca atacagcatg caagtaacaa tattttaaaa ttaatgaata gaaaaactac
    70981 taaagaagat atattaaata aaatcaatct gataagaagt aatataccag atgctatact
    71041 tagaactaca ataatagtag ggtttcctgg tgaaacagaa gatgacttca aacaacttgt
    71101 ggactttgtt gaagaggtta aatttgatag acttggtgca tttgcatatt caagagaaga
    71161 agatacacca gcagatagat tgccaaacca tatagatgaa gaagtaaaaa tacaaagaag
    71221 agatacttta atgatgattc aacaaaaaat atctgaagaa cttaatgaca aaaagatagg
    71281 aaaaacttat gaggtgttaa tagaagaaca gatagaagat aatgtatata caggaagaac
    71341 acaaggtgat gcagaggaaa ttgacagtat agtgtatgta aaaagtgtag acaatcttga
    71401 agtaggagaa tttgtaagtg ttcaaataaa tgatgcaatg gaatacgatt taatgggaga
    71461 tgttttatat gaacttgcct aacaagttaa ctttgtttag aatattttta ataccagtat
    71521 ttgttttaat tatgttgctc aatataccaa ataaattttt aatagcttgt attattttta
    71581 taatagcttc aattactgat gctttagatg gaaaaatagc tagaaaatac aatctagtca
    71641 ctgactttgg aaaatttatg gacccattag cagataagtt attggttatt tcagcactta
    71701 catgtatgat agaagaccat cttgtaagta gttggatggt aattataata gtggctagag
    71761 agcttacagt tagcatatta agagctatag ctgctgctga tggaaaagta attgctgctg
    71821 gaaacagtgg aaaacttaaa acgataactc aaatggtatc tatagtgttt ttattgttag
    71881 gtgctcagtt tgaaaatgta ttgatattaa atattggtga aattctcatt cttatagcta
    71941 cactacttac attatattct ggatgggaat atctatataa aaataaagag ctttttatgt
    72001 cttctaagta aaaaattatg ctttaataaa taaaaactaa tgattaataa ataaaaaata
    72061 acaacttaaa attttaaaaa tgta
//
LOCUS       DAYAKB010000014        71300 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.014, whole genome shotgun sequence.
ACCESSION   DAYAKB010000014 DAYAKB010000000
VERSION     DAYAKB010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71300
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.014"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..278)
                     /locus_tag="ACGI3L_001084"
     CDS             complement(<1..278)
                     /locus_tag="ACGI3L_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196811.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEIL"
     gene            complement(279..1151)
                     /locus_tag="ACGI3L_001085"
     CDS             complement(279..1151)
                     /locus_tag="ACGI3L_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9196812.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLIDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(1166..2875)
                     /locus_tag="ACGI3L_001086"
     CDS             complement(1166..2875)
                     /locus_tag="ACGI3L_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196813.1"
                     /translation="MSSIKAISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKINSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            complement(3022..3603)
                     /locus_tag="ACGI3L_001087"
     CDS             complement(3022..3603)
                     /locus_tag="ACGI3L_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HFG9196814.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            complement(3662..3802)
                     /locus_tag="ACGI3L_001088"
     CDS             complement(3662..3802)
                     /locus_tag="ACGI3L_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HFG9196815.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(3814..5130)
                     /locus_tag="ACGI3L_001089"
     CDS             complement(3814..5130)
                     /locus_tag="ACGI3L_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9196816.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(5124..5834)
                     /locus_tag="ACGI3L_001090"
     CDS             complement(5124..5834)
                     /locus_tag="ACGI3L_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9196817.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(6273..6848)
                     /locus_tag="ACGI3L_001091"
     CDS             complement(6273..6848)
                     /locus_tag="ACGI3L_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HFG9196818.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(7141..7419)
                     /locus_tag="ACGI3L_001092"
     CDS             complement(7141..7419)
                     /locus_tag="ACGI3L_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HFG9196819.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(7728..8489)
                     /locus_tag="ACGI3L_001093"
     CDS             complement(7728..8489)
                     /locus_tag="ACGI3L_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HFG9196820.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(8658..10733)
                     /gene="bclA3"
                     /locus_tag="ACGI3L_001094"
     CDS             complement(8658..10733)
                     /gene="bclA3"
                     /locus_tag="ACGI3L_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HFG9196821.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAVGATGIGIT
                     GPTGPTGATGADGATGVTGPTGATGATGADGVTGPTGATGATGFGVTGPTGPTGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATG
                     ATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLV
                     GPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATG
                     LAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGATGPTGA
                     TGATGATGPTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDL
                     TNAAGTLTNFAFSMPRAGTITSISAYFSTTAALSLVGSTVTITATLYQSTAPNNSFTA
                     VPGATVTLAPPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAG
                     YASAGIAIN"
     gene            complement(10800..11876)
                     /locus_tag="ACGI3L_001095"
     CDS             complement(10800..11876)
                     /locus_tag="ACGI3L_001095"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9196822.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTDGGFKSDDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(12188..12772)
                     /gene="clpP"
                     /locus_tag="ACGI3L_001096"
     CDS             complement(12188..12772)
                     /gene="clpP"
                     /locus_tag="ACGI3L_001096"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFG9196823.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(12769..13251)
                     /locus_tag="ACGI3L_001097"
     CDS             complement(12769..13251)
                     /locus_tag="ACGI3L_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196824.1"
                     /translation="MKTNTDVIMEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFT
                     NVVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQ
                     VYRNKDEFYPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA
                     "
     gene            complement(13450..14865)
                     /locus_tag="ACGI3L_001098"
     CDS             complement(13450..14865)
                     /locus_tag="ACGI3L_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9196825.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            14980..15648
                     /locus_tag="ACGI3L_001099"
     CDS             14980..15648
                     /locus_tag="ACGI3L_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFG9196826.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(15824..16342)
                     /locus_tag="ACGI3L_001100"
     CDS             complement(15824..16342)
                     /locus_tag="ACGI3L_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9196827.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            16494..16817
                     /locus_tag="ACGI3L_001101"
     CDS             16494..16817
                     /locus_tag="ACGI3L_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9196828.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            complement(16822..17406)
                     /locus_tag="ACGI3L_001102"
     CDS             complement(16822..17406)
                     /locus_tag="ACGI3L_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HFG9196829.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(17455..17721)
                     /locus_tag="ACGI3L_001103"
     CDS             complement(17455..17721)
                     /locus_tag="ACGI3L_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFG9196830.1"
                     /translation="MAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDYLIKVL
                     AEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            complement(17776..17910)
                     /locus_tag="ACGI3L_001104"
                     /pseudo
     CDS             complement(17776..17910)
                     /locus_tag="ACGI3L_001104"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
     gene            18792..20330
                     /locus_tag="ACGI3L_001105"
     CDS             18792..20330
                     /locus_tag="ACGI3L_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9196831.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(20602..21315)
                     /locus_tag="ACGI3L_001106"
     CDS             complement(20602..21315)
                     /locus_tag="ACGI3L_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9196832.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(21763..23142)
                     /locus_tag="ACGI3L_001107"
     CDS             complement(21763..23142)
                     /locus_tag="ACGI3L_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9196833.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(23427..24218)
                     /locus_tag="ACGI3L_001108"
     CDS             complement(23427..24218)
                     /locus_tag="ACGI3L_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HFG9196834.1"
                     /translation="MKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLMF
                     NSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYITK
                     PLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLLF
                     YDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMST
                     IPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(24218..25072)
                     /locus_tag="ACGI3L_001109"
     CDS             complement(24218..25072)
                     /locus_tag="ACGI3L_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9196835.1"
                     /translation="MSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFDVVV
                     NMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSEEIC
                     NRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFTSNP
                     VQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFKMIIENIVEFITGTMIPLVLL
                     PETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYKRMR
                     TLFDGVGI"
     gene            complement(25059..26054)
                     /locus_tag="ACGI3L_001110"
     CDS             complement(25059..26054)
                     /locus_tag="ACGI3L_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9196836.1"
                     /translation="MSIIELNELTKAYRRFEKKAGFMGSVKSLFNRKYTEKTAILSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            26757..27713
                     /locus_tag="ACGI3L_001111"
     CDS             26757..27713
                     /locus_tag="ACGI3L_001111"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9196837.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(28106..28996)
                     /locus_tag="ACGI3L_001112"
     CDS             complement(28106..28996)
                     /locus_tag="ACGI3L_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196838.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(29174..29872)
                     /locus_tag="ACGI3L_001113"
     CDS             complement(29174..29872)
                     /locus_tag="ACGI3L_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196839.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(30408..31475)
                     /gene="rsgA"
                     /locus_tag="ACGI3L_001114"
     CDS             complement(30408..31475)
                     /gene="rsgA"
                     /locus_tag="ACGI3L_001114"
                     /inference="COORDINATES: protein motif:HMM:TIGR00157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFG9196840.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            complement(31472..31873)
                     /locus_tag="ACGI3L_001115"
     CDS             complement(31472..31873)
                     /locus_tag="ACGI3L_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HFG9196841.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      32670..32766
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            32820..32996
                     /locus_tag="ACGI3L_001116"
     CDS             32820..32996
                     /locus_tag="ACGI3L_001116"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196842.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            33406..34044
                     /locus_tag="ACGI3L_001117"
     CDS             33406..34044
                     /locus_tag="ACGI3L_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196843.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(34517..35875)
                     /gene="rlmD"
                     /locus_tag="ACGI3L_001118"
     CDS             complement(34517..35875)
                     /gene="rlmD"
                     /locus_tag="ACGI3L_001118"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFG9196844.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(36050..37810)
                     /gene="pyk"
                     /locus_tag="ACGI3L_001119"
     CDS             complement(36050..37810)
                     /gene="pyk"
                     /locus_tag="ACGI3L_001119"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFG9196845.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(37862..38821)
                     /gene="pfkA"
                     /locus_tag="ACGI3L_001120"
     CDS             complement(37862..38821)
                     /gene="pfkA"
                     /locus_tag="ACGI3L_001120"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFG9196846.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(39030..42599)
                     /locus_tag="ACGI3L_001121"
     CDS             complement(39030..42599)
                     /locus_tag="ACGI3L_001121"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFG9196847.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(42756..43703)
                     /gene="whiA"
                     /locus_tag="ACGI3L_001122"
     CDS             complement(42756..43703)
                     /gene="whiA"
                     /locus_tag="ACGI3L_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFG9196848.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(43720..44145)
                     /locus_tag="ACGI3L_001123"
     CDS             complement(43720..44145)
                     /locus_tag="ACGI3L_001123"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9196849.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(44214..45320)
                     /gene="yvcK"
                     /locus_tag="ACGI3L_001124"
     CDS             complement(44214..45320)
                     /gene="yvcK"
                     /locus_tag="ACGI3L_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFG9196850.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(45332..46189)
                     /gene="rapZ"
                     /locus_tag="ACGI3L_001125"
     CDS             complement(45332..46189)
                     /gene="rapZ"
                     /locus_tag="ACGI3L_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFG9196851.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(46220..46933)
                     /locus_tag="ACGI3L_001126"
     CDS             complement(46220..46933)
                     /locus_tag="ACGI3L_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFG9196852.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(46937..47851)
                     /gene="murB"
                     /locus_tag="ACGI3L_001127"
     CDS             complement(46937..47851)
                     /gene="murB"
                     /locus_tag="ACGI3L_001127"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFG9196853.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(48124..48894)
                     /locus_tag="ACGI3L_001128"
     CDS             complement(48124..48894)
                     /locus_tag="ACGI3L_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFG9196854.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            49212..50693
                     /gene="cls"
                     /locus_tag="ACGI3L_001129"
     CDS             49212..50693
                     /gene="cls"
                     /locus_tag="ACGI3L_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFG9196855.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            51011..51508
                     /locus_tag="ACGI3L_001130"
     CDS             51011..51508
                     /locus_tag="ACGI3L_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HFG9196856.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            51525..53411
                     /locus_tag="ACGI3L_001131"
     CDS             51525..53411
                     /locus_tag="ACGI3L_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="HFG9196857.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            53434..55215
                     /locus_tag="ACGI3L_001132"
     CDS             53434..55215
                     /locus_tag="ACGI3L_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent [FeFe] hydrogenase, group A6"
                     /protein_id="HFG9196858.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(55355..57151)
                     /locus_tag="ACGI3L_001133"
     CDS             complement(55355..57151)
                     /locus_tag="ACGI3L_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HFG9196859.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENIILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     RGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(57363..58292)
                     /gene="hprK"
                     /locus_tag="ACGI3L_001134"
     CDS             complement(57363..58292)
                     /gene="hprK"
                     /locus_tag="ACGI3L_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFG9196860.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(58292..60109)
                     /gene="uvrC"
                     /locus_tag="ACGI3L_001135"
     CDS             complement(58292..60109)
                     /gene="uvrC"
                     /locus_tag="ACGI3L_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFG9196861.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(60368..63193)
                     /gene="uvrA"
                     /locus_tag="ACGI3L_001136"
     CDS             complement(60368..63193)
                     /gene="uvrA"
                     /locus_tag="ACGI3L_001136"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFG9196862.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(63212..65182)
                     /gene="uvrB"
                     /locus_tag="ACGI3L_001137"
     CDS             complement(63212..65182)
                     /gene="uvrB"
                     /locus_tag="ACGI3L_001137"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFG9196863.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(65369..66631)
                     /locus_tag="ACGI3L_001138"
     CDS             complement(65369..66631)
                     /locus_tag="ACGI3L_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFG9196864.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(66694..67998)
                     /locus_tag="ACGI3L_001139"
     CDS             complement(66694..67998)
                     /locus_tag="ACGI3L_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9196865.1"
                     /translation="MKLKRKLATGLAITLLLCSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(68029..68889)
                     /locus_tag="ACGI3L_001140"
     CDS             complement(68029..68889)
                     /locus_tag="ACGI3L_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9196866.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(68933..69802)
                     /locus_tag="ACGI3L_001141"
     CDS             complement(68933..69802)
                     /locus_tag="ACGI3L_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9196867.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(69786..70856)
                     /locus_tag="ACGI3L_001142"
     CDS             complement(69786..70856)
                     /locus_tag="ACGI3L_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9196868.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        23225 a        12163 c         8474 g        27438 t
ORIGIN      
        1 agtatctcat ttatattacc cgaataatct tttgaaaaca cataaattat tgtgattgct
       61 gacattattg gtataaaaac atctgatatc tttataattc ctaaccatcc tgctatagaa
      121 tatgtatcca ttataggtac atcattataa aatattaact cattataatc taatatgcct
      181 gtaataaata tgcataagat agaaataatt acaaatatta acacatgttt aagctctatt
      241 tttttaagct caaattttat taactccaat atacacattt attttaactc cttatgtaaa
      301 aagtttatat aagcatcttg taaagttgta tctatcctta agctatcttt aagtttctct
      361 gtatttttac ctatatactt tacttgcaca ccatctttaa ctctcctata atcaataata
      421 tcaatattac gttctaaata ttcaaattca tcattagaaa ctactaccga atacacctca
      481 accatatcaa taaacttatt aattgtacca tcatataata ttttgccttg atttaatata
      541 attaatttgt cacagttaaa ttgtatgtct tctactatgt gagttgaaat taatactata
      601 gaatttttac ttatttctgg taacaatctt ctaaattcat tcctttgctc tggatcaaga
      661 ccaactgtag gttcgtccat aactattaac ttagaatcac ctattaaagc ctgtgctata
      721 cctagtcgtc tctttacacc acctgagtat gtacctattt ttttatttat aaacttgtcc
      781 agattaactt ttgatactac tttttgtata tgtttcttta aatcattctt agatacacct
      841 ctcattttag ctacaaattc taagtattct tgcccattta tattattata catatcaaaa
      901 tcttgaggta catatcctac atttgccttg attttctcat tgtttttgct atactttata
      961 ttatttaatt ctatctctcc aattgaagtt tcataaagag tcactaataa cctcattaat
     1021 gttgattttc cagcaccatt aggacctaat aatgcaacta ctccatctat tagggttaaa
     1081 tttatattat ccaaagcttt tttatttttg taattaaaat ttagatttct tatttctaac
     1141 ttgtttatca tattaacctc ctttattatt tatctattat aaggatattt cctgaaagcc
     1201 aatgataaat agttatgcta attttctctc cctttgagtc ttcatataaa aattcattgc
     1261 taggtaagtc agcaactaat atcatattaa ttttttttct ttttattgat tccataacat
     1321 tatctacttc atctacatat tttttagcat ctacagatgc tttgctatca cctaatattt
     1381 catttcttgt ttcaattaaa aatttaattt tttcctctat atccatattt acattactat
     1441 ctgatggata gattattttt atatcatctt ttacctcttc tttaaactca cctgcatata
     1501 ttgcaatatc atttgacttt ccttcaaata tataatcttt ttttaaaaaa ttactagtct
     1561 tattcagtaa aggtaaattt gaatagacat tatttttaga acttaaattt attttataag
     1621 ccatacaact tgattgattt acttttgggt accacgctaa agaacctggt ggaagcataa
     1681 tatcatcttt agtagctata tatttatttt gattccaaga tgtcaacaca ttaatatagc
     1741 cttcatactc tatatctaat gtcacctcgt cattaggctc taaactttcc tttaaattaa
     1801 cttcaattaa atcctttttt ttgttaaatt ttatattttc cgaatttatt tttatatatt
     1861 ttatatcaaa tatttcatct aaaatcatat taatatttgt taactcttca tttgatgtgt
     1921 ttaataaaac aattctatct tttatatttg acttgctttt aaagtcaatc ttcatatcat
     1981 gcgattttat tttaatatca ctaatattag atttctttaa atactctcca taactacgct
     2041 cctcatctct atatgttgac atatctattg atatataatt taatccaata aataaaatac
     2101 tgtacactac tataactatt aatgatttaa tctgtttctt tctaatatca tttaatatca
     2161 gatatgctac tattattaaa gtaattgcaa atagtgtagg tataatctta tctataacat
     2221 atgctgaatt attaactttc cctacaaaat cagaatagta agcatatgat tgatcttcaa
     2281 atatgttaag tgatttaaat aatgctttaa aaaatggttc tttaatatca ataactctat
     2341 ccaacatatt agttgatgtt aaatataaaa atactgatga taaggtaatc tttagtatta
     2401 aattatttat aataactgaa ataaatgata tcactataga taaaatagta agtggtaaaa
     2461 accattcaaa tatcaatata aatatagttg atttaatcgt tacaattgac aatgttctta
     2521 ttaaacttga gtatgctata gcatatataa ttggtatgca acaaaatata aagttgtttc
     2581 tagttacagc aacagaaata cctaaaaaat aatcaaaatt atttctacat aatattttta
     2641 cagtatcata actttttctc atataaaaaa ttacatttaa catggttaaa atactaattg
     2701 tcatacaagt atatacactc aaggataagt aatcattaaa tgaaattcct ctattggata
     2761 tatgtgtcca tcgttgtatg agatggtaat ttataataat aattgttatt gcaaataaaa
     2821 tattttttct aattattttg gttataaagt ctgatatagc cttaatacta ctcatattta
     2881 tgcccctcct agccagtctt ttgatacaac ctacaataga ttcaactata tttaataagt
     2941 tcaaatactt accttgacat tattttttta aagttaatat taattagtga agttaattaa
     3001 tttagaaaat gttttataat cttactgatc actattaacc ttcattccaa tatatattaa
     3061 tatagcaatc caatatatag aaattattgc ataaatcaca tattgctgaa aaatattaag
     3121 tattttacat aaaataatta aacatattat tacgaatagt attttttgca cagtctttct
     3181 ataatgcttt ttctcacttt cactaagagg tttgtttcta tgttctaaag gagctaactt
     3241 gtaaattgtt agtatactaa taatcattaa taatactaat aaatacttat atttatttat
     3301 atctatatta ttagctgaaa aaatagttat caaataaata actgcaaatg ttaatgtaca
     3361 ctctttataa ttcctagcat gataacctcc tgtgaactgt cttaaagtgc aataacaact
     3421 taaaaatata actgtatgta taaatctatc aaaaataatt cctataaata atgctaccaa
     3481 aatattaact atgaaataaa tcaaagtttc aaatccatat ctatatattt caaaatcttc
     3541 actttctaca atctcattat taactaatat attggcaaat ttatatgata atcttttaaa
     3601 catatttcct cctcaacatg taaaacctct cctttaataa gaagaggtcc ttttattaat
     3661 gttatttttt tagtttttgt aaagcttgtg gctcttttgc ctgatgtgct acccaagaac
     3721 ttgcactgtt tgctgataat acagctatcc caaaacttaa tgctgagatg tttttaagta
     3781 agtttaacgc tatttttttc attttgtact ctcctaactt tttattggta tcattatttt
     3841 taatataaac tcattatctg agtaattaac tattgtttca ccaccatatt tatttactat
     3901 atatttaata ctagcaagtc ctattccatg tatcttatca tcatccttac tagtttgaat
     3961 acgtttatca ataagtttaa tatcatttac cttagtattt ataaatttta ttattgcaaa
     4021 tttatttata tatgtagctt taacttctat tcttttttct atctcattat ttatatccat
     4081 acatgcttca attgcattat ctagtgaatt tgcaaatatt gaacatatat cattattttt
     4141 aataaagttt aatttagata tatttatgtt atcttcaatt tgaatatcat actttttaca
     4201 aatacttatt ttttctgcta aaattaaatc taatgtttta tttccagtat ttttaaaatg
     4261 ttcaaattca cttatctgaa actctaagtt atttatatat gatataattt cttctttagt
     4321 gtcataattt tttatacaaa tcatatggtt tttcaagtca tgataaacat attttaatct
     4381 atcatgaact tcgtttatat tttcataatt cctgtagttt gtttttattc tttcatttat
     4441 aagttcatac tctagattta atttatcgtc ttgtacaatt ttccctatta ctattaaaag
     4501 tattatactt gatgataaaa tcaataaaat tgcaaatata aatataaata agttttctgt
     4561 agtaattgta ttgactctta aattatattc aaatataagt aataagctaa ctatattaga
     4621 taatataggt attcctatta gtatcatatc tttaggttta aaatctaaag ataatttaaa
     4681 atacttaaac aatataaaac ctataaataa aaataccttt gacataataa tagcttgtat
     4741 tctaaataag ttttcatgtt gtgttatgtt aatattattt aatttattta taaatactac
     4801 tagacctact gcagaacctt cagcaaccat taatcctagc caaaacaata aactaactat
     4861 tatactttta tagattttat cttcatatga tgttatataa aatgatattc ctattaccat
     4921 acatagaaga atcttaatat ttggaaacac tttaactaca tttatgtatg ccataaatat
     4981 aattataatt attgttgtaa atatatatct tatattagat attttcctct ttccaactaa
     5041 gtggattact aaaaaaaata taatccaatc tatagtacct gaaactaaat taataatatt
     5101 ccaaaatcct acacttaaat ttgttagcat actatgtccc ctaatatatt agttatcgca
     5161 agcttcaagc ctttaaccct atatttactt attggaatac tttttccatc tactataaca
     5221 gtacttccac tcattgattc tactaatttt aagttaacta tatagctatt atgacatcta
     5281 aaaaatccat attcatttaa tatcttttct attttagata tactcatttt agtaatatac
     5341 atatcatcat gtgtataaat caatatattc ggtctatctg tttctatata agtaatagaa
     5401 tctattttaa ttcggtctac ataatttttt acatttatag ttaagtaatt atttctcttt
     5461 ttcatcatct catttataca aggtaataca cttttagaaa ttttttcttt atttattggc
     5521 tttagtatat atctgtatgc ttttacctca taaccttctt gcataaactc tacaaatgaa
     5581 gtaacaaata ttatttctaa cttatgatca aactctctta tcttcctagc agtatccata
     5641 ccatttattg ttttcatttg tatgtccata attaatatgt ctaaatcttt aggatagtta
     5701 tttagtaact cttctcctgc tgaaaattca tatatgttat aatttatagg atatgaactt
     5761 aatatttcac ttaatatatc ttttattttt attcgataat gtagttcatc atcacatatt
     5821 cctatattaa tcacaattct taaacatcct ttcttatata tttttaataa aaatatataa
     5881 atttctattc attttacata ttttaacata cttctgtagt aaatagctat ttagatttta
     5941 attttagctt tttggacatt aagtattact ttttggattt gcaatctatt ttgattttca
     6001 ttataataca attttttaat atatattaaa tatatttagg gattttaata aaatattcct
     6061 cgaaaagttt ttaatatcta gtttttgtta aataaaaagt atgcaccttc ctttttatag
     6121 taatatttta attatcgcta taattttgaa gaatacacac tatattttaa atattaatat
     6181 aaaacatatt aaaaaatagt ggctttaaat tttttaaagc cactattttt ttaaatgatg
     6241 ttcctgaaaa tatattaagt tagttattct aatcaatttg aagacttttg cttctccttg
     6301 cctatatcta acataatttc ataatttaat ttacctttct ttaaatcaac tcctgagtta
     6361 cttctaataa tcccacaatc caacatttcg tcaaatacct tcctagataa acctagtttc
     6421 tcacgtaata atgttgatac ctttaactga catggatatt tactaataat atgaacttgt
     6481 gtaaggtcat taatattaat ttcttgtcct actattttat actctggaat accaacttct
     6541 gctccatttc tatgtaaaag ttccatattc atagcatatt gcttaacaag attataatcg
     6601 tttgtatgga attgttctag tatttctgga tttaagcttt ttggattaac acgagaatat
     6661 atagttgagt tccatgttga atcacaattt gaacacttgt atattaacca tatatccaaa
     6721 tatttatgtt gagcattaac cctaaataaa cctgaacaaa tatattcagt cttttttcca
     6781 cattttttac aatacctaat tacaggtaac tgggagatat attccacctc ccaagtaatt
     6841 tttttcataa atgcaatttc ctttctataa gattactaaa ttaatagaaa gttatgaaaa
     6901 ggtggaatat aatcaagtat ttttttcaaa acaagacctc ctaattttaa taaattttaa
     6961 tttcaaacat ataaaaagct actacttctt attagatact ttacaaccag ctttgttagc
     7021 tactgtataa gttattgaaa ttacttaaat tatatcatcc acttaaaaga aactatacct
     7081 caaacacttt tatcaaaaga aaatgagcca gtataattat aaaactatac tggctcatcc
     7141 ttagatatct tttctttttt cttgtaatac aattctttgg atacttttca aagataaata
     7201 atacttttcc gataaatatt gcaaatcata tccaacttga tagtcttcgt aaatctgcat
     7261 atttctaatt gacaactcct cacgagtagg tgtattactt ccccattctt ttttattatt
     7321 agattttcta ggaatataga tacattcacc atctacatat tcctgtatta attcaagtaa
     7381 ttcttctggt aatatatgta ttgctttttt atagctcatt ttgctctcct attaaatagt
     7441 aatttttcat taggaatagc aaagggctat ttatatatta aatttcatag ttgcaatagc
     7501 ccttgctatg caaaaataaa gattaaatca aacataaaat ctcaaccctc cttatatatc
     7561 acagcgatac atataagtct atcaacagta taactggttg tcaatcaaca caaattattt
     7621 atccattttt taaacacatt tatttagttt ttatattata tttattttga taactaaaat
     7681 tttttcatta taaactatct ttaaaattat tagtcaactt aaatccatta tcttgatggg
     7741 tttattactg aacaaggaac tccaactata cactttccac aaatatcaca tccacctata
     7801 taagtgtatt ttttttcatt tatcatacac atttcataac acttattcct attaaatcca
     7861 tcttctttta aagcttcttt cacgcatttg ttgacacatt ttttgcaact attattatgt
     7921 ttatacaagc agtattcatt ttctggtctt ttagttggct ctaattctaa acttgtgatt
     7981 atgcttccta ttcttccaca acaccctttt tctgtaataa gcatattatt taaaccaaaa
     8041 gttccaagac ctgctatgaa tgctacatgt ctttgtgacc agtcacttac caatttttca
     8101 ctgtcaaaat tatacgaccc aggaatagca tatgaattag cccccatctt ctctagttct
     8161 tcacataaga aatcatttaa atttgaaatc aacatattag tttctatgta cgctcttgcc
     8221 catatttcag aacattcaaa ccctccaata ttactattat ttacactttc atcaaaaggt
     8281 ataaaatatg taattatagt ttttccattt tccagaaaat cttttggcat agcatgagat
     8341 gttcctacaa cactttttag cttctgaaac atatcatctt cagcagatgc ataagcaaac
     8401 aaaagttctt gccactttgt agttatatta tttgatttat gataattttt tacaaagttg
     8461 ttcattgata tttcaatctt atttttcata gtatcacccc tagataattc tatatttcca
     8521 atttaatgtt attattttat attatataat agtattttat aatatgcgca ctaattaata
     8581 ttaaaactat gttcatcaat cattcttaaa aaagctccta atatcaatac gatattagaa
     8641 gccttttctt atctaatcta atttattgca attcctgcac ttgcatatcc tgctacagta
     8701 ttaactaatg aaagacctga agctgttgca gtaaatacta gtaagaatcg agtttctgct
     8761 gttgctgcta tatttaatcc tgttacaatt ccactagaaa ttgaaccaac tgataatatt
     8821 cctgtaagtg gtggagctag tgtaactgtc gctcctggta cagctgtaaa tgagttattt
     8881 ggtgcagtag attggtaaag tgttgctgta attgtaactg ttgagccaac aagtgaaagt
     8941 gctgctgttg tactgaagta tgctgaaata gatgttattg ttccagctct tggcattgaa
     9001 aatgcaaagt tagtcaatgt tcctgctgcg tttgtaaggt ctattactcc accaactata
     9061 cttaatcctg gagctgaact accaaagcca acaaaacctg gtgtacctac taatcctcca
     9121 gctatagttg taagtgatag tggtatacct gatgcaaaag gtattattgc actagcacct
     9181 gttggacctg ttgctcctgt tgctcctgtt gctcctgttg gacctgttgc tccggtcgct
     9241 ccggttgctc cggttgctcc tgttggacct actaatccat ctgcccctgt tggacctgtt
     9301 gctcctgttg cccctgttgc tccatctgct cctgttggac ctgttgctcc tattgggcct
     9361 gttgctcctg ttgctcctgc taatcctgtt gctcctgttg ctcctgttgg acctactaat
     9421 ccgtctgctc ctgttggacc tgttgcccct gttggacctg ttgctccatc tgctcctgta
     9481 tttcctgttg ctcctgttgc tcctgttgga cctgctactc catctgctcc tgttgctccc
     9541 gtcgctcctg ttggacctac taatccatct gcccctgttg gacctgtcgc tcctgttgct
     9601 cctgttgctc ctgttattcc tactcctgtt gcccctgttg gacctgttgg gcctactaat
     9661 ccatctgctc ctgttgctcc tgttgctcct gttggaccta ctaatccatc tgctcctgtt
     9721 ggacctgttg ctcctgttgc ccctgtcgct ccggttgctc catctgctcc ggttgctcct
     9781 gttgccccgg ttggtcctat tagtcctgct gctcctgttg cccctgttac tcctgttggg
     9841 cctgttgctc ctgttgctcc cgttgctccg gttggaccta ttaaccctgt tgctcctgtt
     9901 attcctattc ctgttgctcc tgttggacct gttgggcctg tcactccaaa tcctgttgct
     9961 cctgttgccc ctgttggacc tgttactcca tctgctcctg ttgcccctgt tgcccctgtt
    10021 ggacctgtta ctcctgttgc tccgtctgct cctgttgctc ctgttggacc tgttggacct
    10081 gttattccta ttcctgttgc tcctactgct cctgttgggc ctgtcgctcc aggtgttcct
    10141 gttgctcctg ttggacctat taatcctgtt gctcctgtta ctcctactcc tgttgctcct
    10201 gttgggcctg ttggacctgt tactccaaat cctgttgccc ctgttgctcc tgttggacct
    10261 gttattccat ctgctcctgt tgctcccgtt ggacctgttg gacctgttac tccatctgct
    10321 cctgttgctc ctgtcgctcc tgttgggcct gttggacctg ttactccaaa tcctatagct
    10381 cctgtcgctc ctgttgggcc tgttgcccct gttgctcctg ttggacctct taatcctgtt
    10441 gctcctgtat tccctgtatt tcctgttgga ccagtcggac cggttggtcc tgttgggcct
    10501 gttgccccta cacctggacc tgttggaccc gttggacctg ttgggccggt tctacctctt
    10561 ggacccattg ggcctgttgg acctacacat gatggtggac agcaatgatg gcaatcacag
    10621 ctattataat catcacgacc attgttacaa tcatcatatt tatcatagcc attgttgtaa
    10681 tcattatcat caaatggtcc aaaatattta tttctactca ttattaaaag cacctcctga
    10741 tatatttgag cttttaagct ctatatataa tatgtcaaat ttagtatgat tgtgacccat
    10801 caactatttt taaatttact aaaataattt tcattgtgca aaacagcact atcattaggt
    10861 ttgatttctt ttgttttttc atgataataa atagctttat ctgattctcc taacctgtca
    10921 taacagacac ttaattgtat agatggtata tatccataac aatcatctga cttaaagcct
    10981 ccatcagtat cattcttatc tcttgttaat gctaccttat accaaaaaat ggcttcttta
    11041 tatttttgtc tatcaaacat atgctttcct atgtcacaac aaatttctgc tcttggctca
    11101 tcaaattcga aacttctaaa caatgaatat aaggcacttt tttcatcatt aattaagtaa
    11161 taacatgtgg ctaaatctct gcaagcactg atacaatcct caatccatcc tcttgatgag
    11221 tctaaaaact tagtaaaacc ttctattgct tctttatacc tagcattata gtacaactct
    11281 ctagaataat agaattggtg tcttggctcc aatgtttttc cttctgaaat cattttttca
    11341 aaaattctaa gatttcttag agggtcctgt ctatgaagct ttttatgaga tattgcaatg
    11401 tcagaataaa atacctctcc aaaaagaggt actacttcat gaatagggtc aacccattta
    11461 tgattagaac ttcttttaaa caatcgttct ctataatatg agagagttgg gttaccattt
    11521 tcatcaaagg atacattgta ttttgccata acaatatcaa tggaagtatc caagctttct
    11581 ttaatcttta ataatttttc tctatcagct tctaaaatta tgtcatctgc atcaagccac
    11641 atagtatagt ctttagaagc tttagaaaat gaaaaatttc ttgcagcaga gaaatcatct
    11701 atccattcga aatcgtacac catgtctgta tattttgaga ctatttcttt tgtggaatct
    11761 gtagaaccgg tatctacaat tataatttcg tctactatat cctttacaca ttctaagcat
    11821 ctgcctataa cttcttcctc attcttaaca atcatgcaca aacttattgt aatcataatg
    11881 tacaactcct ttgtcttcta tatattgcag acataagtaa tatatggtat tttctcttgt
    11941 tttgttatta aatttataaa aacttttgac gacagaaagt tactaaagaa ccttatcttt
    12001 tatgtatttt ttatagtaga atttattaaa cttgaaattt ggtaataatt gtcgaaatga
    12061 taaaaccata tttaatttca tacaaaaaag agtgtcccat aaactaaaaa gttcattttg
    12121 agacactctt atttaatatt atatatatat ttgtaaaaca gacattttaa tatgatactt
    12181 tgatacttta ttcattccta ttcattatat aatcaatcag cccgtactct ttagcctcta
    12241 gtgcagtcat aaaattatct ctatctgtat ctctcctaat atcttctatt gatttacctg
    12301 tattttcaga aagaatttta tctaatcgtt cttttatttt caatatatta tctacagcta
    12361 tttttacatc tgttgcttga cctttagctc ctcccattgg ctgatgaatc ataatctctg
    12421 aattgggtaa agcacatctt tttccatgtg ttcctcctgc aagtaaaaaa gcactcatgc
    12481 ttgcagccat accaatacaa atagtcgata catcacatct gacataattc atagtatcat
    12541 atatagcaaa tcctgatgta gcagagccac cagggctatt tatatatata attatatctg
    12601 aatctgggtc ttctgattct aaaaacagta attgagctac tactaaactt gcaatagcat
    12661 cattaatttc ttctcctata aatataattc tatcttttaa taattttgaa tatatatcat
    12721 aagacctttc cccttgacct gtttgttcaa ttacatgtgg cactaaactc atgctacttt
    12781 cacctcacaa ttaatattaa agttcagata agaattgatt tcatctcttc tttgtttata
    12841 attcatattt gcataagaaa tacatttttc actttgaatt tgatgattta gatttaaaac
    12901 aaatctctgt tgaataggat aaaattcatc tttatttcta tatacttgtg gagattcttt
    12961 atataaattt ctaaatgcta gtgtaaaaga ttgatgtgta gaatatccta ctgtaatagc
    13021 tatgtctata atatatttgt ctgtaaatat aagttgtcta gctgcttcag taagtctcct
    13081 cctctgtatg tattgatgga tagtacatcc tacaacattt gtaaacattc tgtgtaaatg
    13141 gtattttgaa taattagcaa tataagctat tttatctaaa tttagatttt ctgtaagatt
    13201 ttcttctata taatcaatta tctccataat aacatctgta tttgttttca actctatcct
    13261 ctccttttaa gtattataac ctatgcaaaa agttttttct taatataaat tgctatctta
    13321 atttagtgta tagcaataaa gtatcgataa aaaaatatca ggtattttta tacaaaaata
    13381 ttaatatata tttcttttaa agtttaaact taattacatc tattatatgt agattgctac
    13441 atgttttatc tatgtacctt gattcatatg tattattttg ctgagtattt ttacaccttt
    13501 ttcaatttca tcaaaactaa gatgagcata acctagtata atttcatagt catattctaa
    13561 tatattctca attgcatatt gttgtatagg ataaactttt atacctgctt caaaaatttt
    13621 atgaattaaa ctttccgtaa atttaacatt atagaaatga gcaactatat gaagccctgc
    13681 tgcttcacct tttattttaa attcattttt aaattccgtg tttaaaactt ttatgaggta
    13741 cttacgtttt ctattgtaca acttcttcat tctaaatatg tacttctcta aacctccatt
    13801 tccaataaat tcagctaata catgttgcaa tattgtttct gtatgaacat cagagtacat
    13861 ttttaaggtt ttatagcttt ctaaaatatt gtctggtaat aacataaatc caacacgaat
    13921 agctggagat aatattttac taaaagaacc tatgtaaatt actttatttg gactaagttc
    13981 ataaagagaa ctaattggtt gaccctcata tctaaattca ctatcataat catcttcaat
    14041 tatatagtaa tcattctctg ttgcacattt aataagctct agtcttcttt gaataggtaa
    14101 aatccctcct aatgggtatt gatgagaagg tgtagtataa acaaaagaaa tcccctttat
    14161 tgattttatt aagttggtat tcattccctt atcatctact ttaattccaa caactgaata
    14221 tccaatagat gaaataacct ttaataagcc tttatgaata gggtcttcta cagcaacctt
    14281 tttattactt ttgtataaaa gctgtgaaat taaagataaa ccttgtgttg aaccagaaac
    14341 aatcataatg tttttgggat tacatctaat tcctctagta cgaaataaat acttagatat
    14401 ttccactctt aaaacccata caccagctgt acttccatat ctgaaatccg aatctgataa
    14461 atcatacagt atttgtttat atagctttga aagttctttg cgtggaaata gttttaattc
    14521 tggaactcct gaacgaaaat ctatataatt tttttgttta ttagtatgta aatctttttc
    14581 atctctaaaa gtatcattta acttaaaatc aactttatgc cctgatattc ctttagctac
    14641 aattgttcca tatccattcc ttgtttccaa atatccttct gcaattaatt gattatatgc
    14701 atctaaaact gtattacgag atacagatag ttcttttgat aaagtcctag atgatggcag
    14761 tttttgctca aactttaagc ttccatccag aatcatatct tttatctcac aataaatttg
    14821 tcttgataat gatatattac tatttctatt aatcgtaatc cacattctaa tacctccaaa
    14881 agtggttcta taaaattact ataaaaatgg aactacaaaa tccactttta atttgctaag
    14941 attatatcat aaaatataaa ataaaaagga gtctatatta tgttagaaat atcacataaa
    15001 gttaaagaaa tttatcccaa tattaaattt ggagttatgg ttataaatat tacacattca
    15061 aaacctaata aagaaaattt tttagttctt aaaaactcta caattaaaaa tattatagaa
    15121 caacacccag aatacaatcg taaagaaaaa attaaaacag agcctgtttc aagttatata
    15181 aagtattata aaaaattcaa gaaaacttac cctgtattgc ttcaattaga atctattcta
    15241 ttaaaatcaa aaggtatccc agatgtaggt gtaacaattg agtcaatgtt tttagcagaa
    15301 ttgaaaaatc ttcttctaac agcaggtcat gaccttgata aaatggaatt acctttgaaa
    15361 atagaattag caaatggaag tgaacatttt tatggtatag gtggtaaaga acatatttta
    15421 acaaaagatg atttattttt atcagataat attggtatat tatctagtat tcttaatggc
    15481 cctgataatc gaacagctat aacaaaagat actaaaaata ttatgtattt tgtatatgga
    15541 cctgataaaa tatcagaaaa gcaaattcaa gaccatttaa atgacataaa acactatatt
    15601 tcaagtgctt ttccagattt aaaagttaat tcaattgata tattttagtt aatatattaa
    15661 aatcctcata aatattttga ataaataaat tagtgaagta tacattctag ttaaactaga
    15721 tatacttcac taaaattaat tatatgtaga tattatttat tttgaatttt gtttataata
    15781 aacactttat tacatttatc ctatgaataa cttaatttta taattaaaga gtttcataag
    15841 aaacaatttc acttaaagga acacgagttt tttcatgtct ctctgggctc tctggtatct
    15901 tagattcata tcccatcaat aatatattta ttggttctag attatctggc aaactaaact
    15961 cttctctaat tatatctgga ttaaaatagc acacccaaac acttgccaat ccaagttcag
    16021 ttgcctgtaa catcatatgg tctgtaacta tacttgtgtc aatatctgta agttgtttcc
    16081 catcaaaagg tcttgtccaa actttgtctt tatctccaca tacaagaatt gctaatggag
    16141 catcatatat attggcagcc ttagaaagtt tatttatacc ttctttttcc tgaataacaa
    16201 tcaatctttg aggttgacga ttaccaccag ttggagctat tcttgcaaca tctaaaacct
    16261 tctcaagttt ttctttttca acctttctat cttgataatt acggcaagaa tatctttttt
    16321 ttgcaagttc aacgaaattc atttatttac ctcctattgt tttattaggc taagttgatg
    16381 atttatttaa cctatgctat aattttatca ctatggtact atattacaat aatgcacttt
    16441 tttgtaatat agtacctaaa aagatacttt aaaataaata aaggagccca aaaatgaaaa
    16501 aatgtttaga taattacagt tgcccaatag aagcaacact tgcattgatt ggtggtaaat
    16561 ataagacact tatactttgg catcttaaag acactatatt gaggttcaat gaattaaaaa
    16621 aattaattcc taaagcaacg cctaagatgt taactcaaca attacgtgaa ttagaatcag
    16681 atggtttaat tataagagtg gtttatcctg ttgttcctcc aaaagtagaa tactcgctat
    16741 ctgattttgg aaagagtatt attccaattt tagattccat gtgtgactgg ggttctgatt
    16801 acttagaaaa tctataaacc attacagttt aaatcccatt gctaatttaa cttcatccat
    16861 ttgttcttta gatgtcaaca tttctaaaag cttaaaagct acatgtggag ctgtttctgg
    16921 acaatatgag gttataatat ttttatctac aacaattggt tcattaacta catttacatc
    16981 aaactcactt aactgtcttt gtcttttacc atttttcaaa tgatatgtag tagctttacg
    17041 attttttaaa acaccacttt ttccaactgg caatgctgcc acacaaatag aagcgattat
    17101 tttttctttt gaattaaact cccttattag atttaaaaaa gatgaatcat atgcttcatc
    17161 ataaaatcca aattcttcaa atcccccagg aatagctaga gcatcataat catcaacaca
    17221 tacttcttct atcgtcttat caactaatac ttgtatatta aatgtgctca taacttgttt
    17281 tttaaatcca caagtcacta catcaatatc atgcccataa tcgttacgag cccatcccat
    17341 aacatctaca aatacactaa attccatagt ttcaaaacct tttgctaaaa aaactaaaac
    17401 tttcatattc tattttcctc ctaaaatata attaacactt tactagtaaa ttatttaaaa
    17461 aatatctttt attgtattaa attcttcttt aattgtagat aaaacaatgg ttgtattagc
    17521 tttttgaatc cccccaattt ccttcaaagt cactgatata aactcttcaa gattacttgt
    17581 atcttctgct aatactttta ttaagtaatc atactctcct gaaatatgat gacattctaa
    17641 tacagtatca tattccaata tagttttctt aaattctttc atacttttag ataaatcagt
    17701 attgataaat ataaaagcca aaagcttata ttttgttttt tcccgattaa tttgaatagt
    17761 gtacttttga attaaatttg actgctcaat tttccttata cgctctgaga ctgctggtac
    17821 tgataaatta atttgtctgc ttatttcaga ggttgaagcc ctactattct tttttagaga
    17881 attaattatt tttaaatcta tttcatccag agctactcac ctccttaatt atttaataca
    17941 attttagcta ataatttaca ttaagtaaat aaatttaatc atttcaataa aatttaatac
    18001 aaatatgtta tttttcctta aaattttagt tttctttaat caaaacacat ataatactta
    18061 aaattattta agttgaatta atgtttttat tttgtataat atattagaac cttaatatat
    18121 cattgaaaat tcaacaataa tagacatata cttctacatg ttgtaatatt tatgaaaata
    18181 gtatccctat atcaaaatta taaaactcat aatcttaatt ttcttataga ctataaaatt
    18241 ttattgatag cgagtcttca aataactttg taatgataga tttactaaat taatataata
    18301 atagtaaata taactttctt attgactata actaagtatt atgataacat aacttaagct
    18361 ataattaata aaacatattt taaataaata agataatcca caaagtacaa aagtacaatt
    18421 taaatacaga taaactagaa ttaatactaa gattaggatg tgaataatta tgatttatat
    18481 agaattagtt aaacttgtta gaaaacttaa ctctacacaa atgtatacga tgaagcgttg
    18541 tgtagaggtt aatctgaaag cttaaagctt tctatcttca tcggcaaata taggtttagt
    18601 atagtttttt ggctatgctt atttaaaatt acctatttgc cgatagataa tatagatttt
    18661 ctggtcatag acaacaatgc ttgtctatga ccttttgttt ttccaaaagc agaggtcggc
    18721 attttacaat gccattcctc tgcttttttt atttccataa attttttaat aaaagaaaag
    18781 gagtttgaat tatgagttta ttaaaagtaa ctaatttatc acaatgtttt atggataaat
    18841 cactgtatga gaaagctaac tttgatttat tcaaaggtga acatataggt gtagttggcc
    18901 aaaatggtac aggtaaaagt acattaatta aaattttatt gggagaagtt gttccagatt
    18961 caggagaaat caagtggcaa cctaatatca atataggcca tttagaccaa tatgcagaaa
    19021 tcaatagaga tacaacaata tcactctatt tacacactgc atttgaagaa ctttataaaa
    19081 tagaaaagga aatgaattta ctctatcaaa aaagtgctat atctgaaaat gagcaatatc
    19141 taatcaaagc atcagattat caggaacaac taatagcaag taatttctat tctatagata
    19201 atgaaataaa taaaatagca aatggtcttg gattagattc aataggaatg aatcgtgttg
    19261 ttggagagct tagtggtggt caaagggcaa aggtaatttt agcaaaatta ctactttcta
    19321 accatgatgt tctattatta gatgaaccaa caaacttttt agataaagaa catgttgaat
    19381 ggctctcaaa ttatttaaat acatttaatg gggcatttat tgtagtttcc cacgattttg
    19441 actttttaga aaaaatttct acaggtattc ttgatataga atttggcatg attaagaaat
    19501 atcatggaaa atattcagag ttccttaaac aaaaatcaca tttaagagaa gattatatta
    19561 gaaggtatca agcacaacaa aagaaaatag aaaaagaaga aacatttata cgtaaaaata
    19621 aagctggagt aaattcaaaa attgcaagag gaagacaaaa acaattggat aaaatagaaa
    19681 gaatagctcc tcctagtttt acaggaaaac caaatattca attttcagaa attgaaatat
    19741 cggctcaaaa tgctcttact ataacaaatc ttgaagttgg atactactat tctttacttc
    19801 caaaattaaa tttctctgtt gatggaggtc aaaaaatagt tataactggt tttaatggaa
    19861 tcggtaaatc taccttgtta aagacattag tcaaagatat tcctcgtata tctggagatt
    19921 tccagttttc agaacaagtt aaaattggtt attatgagca agatttaaaa tgggaaaatc
    19981 ctgataaaac cccacttcaa atagtagcag ataaatatcc aaaattaaat acaaaagaga
    20041 ttagacgtca tctagccaga tgtggtgtga aggaagagca tgtttcaagg agtgtatcta
    20101 ctttaagtgg tggtgaacaa tctaaggtta aattatgttg tatgatgtta tctccttgta
    20161 attttcttat cctggatgaa ccaaccaatc actttgatgc agagacaaag gatgctttac
    20221 aaaatgcttt gaaacagttt agaggaagta taatcctagt ttcccatgaa gaaaaatttt
    20281 ataaaggttg gattgataaa gtatttaata tagaaaaaca attagtataa gtttatacac
    20341 aatatacaat attatttaat tagtatttca atgcaaattt taatgttcta gttaatgttt
    20401 cactgcaaat aaactaaaaa aattttatta gaagataaag tacattacca ggatataaac
    20461 ttaatgaggc tatctcaaaa tagagataga cctcttcttc attgttgaga taacgaaaat
    20521 atatttgatt ttacccataa aagaatgcct cattaactaa aaattcaact tgagatatct
    20581 tcattaatat taaaatctat tctaatcgat tctattcaca agtttatatc ctagtccttt
    20641 aactgttata agtattttag gatttgaggg gttatcttca attttttctc ttatatgtcg
    20701 tatatgcacc ataattgtat tgtcacaaat actactatat actccccata cttgttcata
    20761 gagtctttct tttcctataa ttttatttac attttgagcc atgtagctta aaagatgata
    20821 ctcccttcca gttaactcaa tctcatttct atctttatat acacggtttc cttctatatc
    20881 aatagtaata tctcctattt taataacttc actatctgat ggtacaatgc tttgatactg
    20941 ttgtctacgt aattgcgctt taactcgaaa agcaatttct cttggactga atggctttgt
    21001 tatatagtca tctcccccac tactaagacc tagtattttg tcaatatcat cattttttga
    21061 tgataaaaaa agaatagaac agtatgaaaa ctctcgaatt tttttacaca cttctatacc
    21121 atctatatct ggtaacatta tatcaagaat gacaacatct ggacatgcta tcttacacag
    21181 cgaaatagca tctagaccat tataagcttt aataatgttt ttaaaaccat catttatgag
    21241 tacttcttca attaaatcta ctatatcctt ttcatcatca acaagtaata tttttttatt
    21301 aaaacatgta tccatattga aatctctcca taaaaattta ttatattcta atcttgcagt
    21361 atcactatct tgttttttat attcactact cttgctttta cattactaat agtaacatct
    21421 ctaatagaca aattcaatca ctatgaaaat taagataagt ttctttaaaa taaagtgtat
    21481 gatacattaa aacctataga aaattaattt catccaaagt ttataatatt agactaatac
    21541 acttacagat acagattaat acaatagtaa aataaaagga gttgtcttaa aattgacttt
    21601 ttctaatcaa actttaagtt caactccctt ttaaactttt atatgttatt tttattaatt
    21661 ctttatatca attataactt taattttcaa tagtatatat ctcccactaa ttgaattact
    21721 tattaaaaca taaaatatct acctaaacta tttatttaat atctacatat atttatatct
    21781 attcttatac ttacatatac aaaaaatggt taaaaataaa gttaaaatct cagcacttgg
    21841 tactgctaac catatcccat ttatatttaa tatatttggc aatatcaata aacctatagt
    21901 tataaatcca aatgtacgta gaaaagataa tattgcagac acctttccat ttgataatgc
    21961 tgtaaacata gacgaagtaa aaatattata cccacaaaaa ataaaactaa aagaaaatat
    22021 ataaaatcca gaccttgcaa tttcataaac tcggcttcct ctttgagaaa aaatctctac
    22081 aatgattggt gaacatgata tagaaaagat aaataccaat aaagatgcta ctgaaataaa
    22141 taatatacaa atcttaaaaa catgatttaa ctgcgtatta ttttcacttc catagttata
    22201 acttattatt ggtgcaacac ccattgagaa acctatataa agcgaagtta aaagaaattg
    22261 agaataaata attattgtaa tagctgcaac cccatcttca ccaattaatt tcatcatcat
    22321 agcattaaat aaaaaagtag taactgctgt tgatagttga cccaccattt cagatgaacc
    22381 attaaaacaa gcttcaaata atattctttt atctagtcta ggtatacaaa atttaagtaa
    22441 ccctttattt tttgaaaaga aaaccatacc tgaaacggta ggaattaggt atcctactcc
    22501 agttgcaagt gctgctccac taatacccat ttgtaacaga acaatgaaca catagtcaag
    22561 aattatatta gcacacccag cacctaacac tagccataat ccaaattgag gctttccagc
    22621 tgttacaaat aaacattgaa ataatacttg tagtatattt gcagaagcaa aaaccaagat
    22681 aataaaaaga tatgaacgac aatatttaat taaaacttca cttgctccta accatataat
    22741 gatataatcc ataaatacaa tacctatacc agtaattatt accccaatta caactcctga
    22801 taatacgatt aaagaaaaag ctttatttgc tccctcaata tcaccatttc ccatcttacg
    22861 tgctacaata gcacttcctc cagtggcaag catagttcca attccaacta taagattaat
    22921 aattggacat acaatattaa ttgctgatag agcatttgta ttaataaatc ttgatacaaa
    22981 tatagtatct acgattgtat acaaccccat aaaaatcatc ataaaaatag taggaaatgc
    23041 aaacttcaat agagtaaata aattaaatct ttgtgccagt aaattatctt gctcataaag
    23101 attatcttgt tcatgatttt ctgaataata tacatcactc attttgttta tttttctgta
    23161 cattaattat ttttaaaata tattccaaac aattagacat ttacagacct cctttctgca
    23221 taagaattat atctaattat ttggatatag ttttaattaa tcttgctttt ttacacaatt
    23281 atatttctac taaagaaact tttaaatcct tactttaata attttatagc tttcagtgcc
    23341 tttagcgcaa atacttgttc acatagttta gtgtcatatg aaacgtattt atatatagtt
    23401 atacattgtc tatttttact aatttattaa ctacttgcac ttttataatg tctcatacct
    23461 aacttccaaa atctccacat aaacaatgta aacaaaaata caattaaaat tgagtatatt
    23521 aatccattaa ttgttattgt cccagccaaa atttgagtcg gaattgtcga cataattcca
    23581 tatggtaaga ttaaatagaa taatacttta aaaacacctt catatattac accaggaatt
    23641 ttcatattca ttggcaataa attatcttct aatctcatta tcgcagaaga tgatataaca
    23701 aaaaatgaaa ctgttctaag tatgatacat acatcataaa aaagtaatgt catcaataac
    23761 accatgaaaa tatatattat tatcataact aaagttatct ctgagtttaa ctcagatatt
    23821 ccatataaaa caataagtat acttgctaga attaatggtg atgaaccaat attaatattt
    23881 tcaaatgtta acctaaatag tgggtctaat ggttttgtaa tatagtagtc taattctcct
    23941 tcttggattt ttcgtggaat atcataaata ccaaaaaaga aaatcgtcat atttatcgca
    24001 tttattaatg agaaagttcc tataaatatt aacatctctc cttgttgcca tccccctatt
    24061 gagtctacat gagaatatat actattaaac attagaagtt gtaatataaa taatgaacta
    24121 tctacaaaaa atgctccaaa aaaatcgaat ctaaatacca tcatctttga taatttcatt
    24181 tttaataaca taaatattat tttcaaattt tttttcatca tatacccacc ccatcaaata
    24241 atgttctcat tcttttatac ataactttat ttactacaga aaaaaataaa acccataatg
    24301 ctagaataat taatccttgt attgcctcat tgctgtttct acctattagt aacatagatg
    24361 gcaaatatgt tgtataataa aatggaaata ccttcataac tgttactata gtttctggta
    24421 agagtacaag tggtatcatt gttcctgtaa taaattcaac aatattttca attatcattt
    24481 taaaaaaact aatctcaaga aatttaaatg acaaaatccc aataaagaag tggagtttca
    24541 tcataaaaat aaaccctaga aaaatcatca aaattgaaat taatatttga actggatttg
    24601 atgtaaaggc aaaatctatt ttaaatataa aaatccatac aaatgcagaa atcatattaa
    24661 atacaaaata aaaacatgtc attccaaaat ttttagcaat aaaataattt tgaacattaa
    24721 ttggaataat catgtacttt gaaaaggtgc ccaattttac acgattacat atctcttcac
    24781 tggtactctt tgacatatca atacctgcta aaaatgagct tattatatag taagacaaca
    24841 tagagttaaa tgtaaaacca gagactattt tattttcacc aaaaattgct ttccataaaa
    24901 tataagcaaa taaaattttt acaatcgtaa acaccatatt aaccaccaca tcaaatctcc
    24961 agataagttg cactttaaag ttaattttgg ctacttcata ataccttcta atactctgtt
    25021 taaatttata aaacattgaa tcatttgaac ttgcttcatt atagttgctc ataatactca
    25081 tcacttcctt tcttatatat tctctctaca atactaccta tatcttcttc ttcaatcatt
    25141 acatctttaa catcatattt atcaaaaatc catttaatcg tttcatttcc tctttctttt
    25201 ggcacaatta ctgatatctt atgatttgtt tgttcaacaa ctttacaatc ttttggaaat
    25261 acaatgttag tttcattgga aaaactaact gttatttttt tatatttttg aaaatgatta
    25321 aatagtttct ctgtagaacc atcatatatt ttacggctat tttctacaac aatacttcta
    25381 ctacagagac tcttaatatc ttccatgtaa tgagaagtaa gtataatagt agttcctttt
    25441 gtttcattta cttcttttag gaaataccta atttgttttt gggctatagc atctaagcct
    25501 atagttggtt catccaaaaa taatattttt ggattatgta gaagggctac tattagttcc
    25561 attttcattc tttctcctaa agaaagcgtc ctaacttgaa catttaaata gtcagatacc
    25621 tcaaataatt cgataaagta atccaagttt tttttatatt cttcattaga tatatcatat
    25681 aattctttaa ataaaagaaa cgtatctgct ggtgtcaatt caaagaatag ttgacttttt
    25741 tggcccataa caacagcata ttgtttttta aaattatttt ctaatttgtt agggtaataa
    25801 cccattacag atatttctcc agaagacggt gcaataatac cagttaacat cttaataaga
    25861 gtagttttac cagctccatt ttgacctatt aatccaacaa attctccttc ttctatcttt
    25921 aaatcaaatg acaatatagc tgttttttct gtatatttcc tattaaataa agactttaca
    25981 ctccccataa atcctgcctt tttctcaaat cttctataag ctttagtcag ttcattaagt
    26041 tcaattatac tcattttaac tacctccata tttcataatt tatataaaaa aagtccacag
    26101 gtatatatct gcctttttct gtgcttatat ttaacagcac aaaaacagaa aactcctgtg
    26161 gactagaaaa attaatgctc tctatttcaa aatagttatc aaaataatac tatacaaaat
    26221 taataaaagt gtagcagatt aaagcctact acaccataat ttaacaaagt aatatatatt
    26281 ttaaatacta tttgttgtca tatgtcagtt atctataaag gcagaataag acacaaaaat
    26341 taaatgtatt aaaaatacac ttgaaatttc tgattataca gaatatatgt gtctccaact
    26401 atttaattgt tggttaccat tatataactc cgacatcaag gcactcctct cataatatta
    26461 ttattgatat catatcataa aggttattta tgttcaagca tggattaata tactaataca
    26521 tttagcttat ttcttcaagg ttgaatttaa atttcattta taatattcgt ttataaatta
    26581 aaaatataat acgtatatta aaactggtca ttttactgta atatttttat tgtaaaagat
    26641 atacttttac ctatacagga tgtaatttct ttagttctat attataataa tattgtaata
    26701 agagttcaac ttataataca ttaaaatata aactgtaaat cttaaggggg taatctatgg
    26761 aaaataatac aatacaaaaa caattaagag atttatcaaa aaaaatttgg catatttata
    26821 ttttaaatcc agaagaagaa aaccttaaat ttattatttc cttattagat gacaaccttg
    26881 cattaattgg aacaggaaaa catgaatttt acgaaacatt agaagaattt attataggtc
    26941 ttgaaaaaga ccaaacagaa tcagagcaaa tagactttga gattatagat gagtggtatt
    27001 catgtaccaa agtcacagac gaagctttta tagtatatgg tactctttgg gtaatagaaa
    27061 aagattacct agaaaaagat atctatgtag aaatggatac tcgatttact atggtataca
    27121 gagttacaga tgatatgatt aaacttatcc atgttcacca ttctattcca aactttgacc
    27181 aaatgaaaga tgagtattac cctaaaacaa taactgaaaa agcacaagaa gcactagcaa
    27241 tggcaaatga atttaaacta aaatcagaaa aagaccttat gactggacta tacaatagac
    27301 atttttttga agtacacata aaagaaatgc ttaaaactgt ttcacatgga tacttttaca
    27361 tctttgattt agataatttt aaacaggtaa atgatatctt tggtcatgtt cgaggagatg
    27421 aaatactaat acatttttca aatattttga ctaaagtatt cgtaaatgat gctattattg
    27481 gaagacttgg tggagatgaa tttgctgttt ttgaatatag taatcaatca aaagagaatg
    27541 ttgaaaataa ggcaaagaag gttttagaat tatgcctaga gagtaattct tgttctatag
    27601 gtatatctaa attagaaaat aactctgata ctttccagtc tttatacaaa caatcggatt
    27661 atgctttgta ttattcaaaa cgaaataata aaggaaactt tagttggttt tagtacaaaa
    27721 gatattaaaa taggcaaatt tattagagta tcttgtccta tatactaata agtaaagtaa
    27781 acaacaagct atctttgcat atatttatat aaaccaacta ttcttaataa aactacaata
    27841 gtcaacatga ccactattat agaatataat aaactaaaaa catgattaat attatatttt
    27901 aataatttta tttttaaaag taagtccaaa atgttatatg ttttgattaa aactgatgtt
    27961 gatataaaaa attttactta aaaaaacact tagaaaggct ttataaagag ccttttttgc
    28021 ttttattgat taaattttca tataaaattc cttattaaat ttcaaatcaa taaaaaaagg
    28081 ctctataaga agcctccccc tatttttatt gattaaatcc taatatagac aatgccttag
    28141 catcatagta agtagtcatc tctcttgttg catcctttaa tttacggtaa tcaaagtcta
    28201 atgatccacc aaaagctgat atttcagacc catcaaacct ataccatttc ccatcaattt
    28261 gtatatagtt ccaagcatga tttaatgatg gatttaatat agatagtgaa tccattccca
    28321 ttaaccttgt taataaatga aagctacttg caaaacttcc acatacacca cgtttatcaa
    28381 ccagattacc atagactatg ttacaatatt tagagtctgc atattttgct tcggttacca
    28441 attttgcagc tctattagct ctttccatct cagatgcatt tctccagtca aagctattta
    28501 aaaaattcct gattactgta agtgtatctt gagcttgttt gtaagaaatc caatttccat
    28561 cagctattac ttctataggg tcaagttttc caaagcctat tctctgatat gagccacctg
    28621 acaatgctgc cgcataaaat cctagccctt ccataccctt atttatataa taatatttac
    28681 catctgctcg aagctcaact ccattgggat ttcctccata gagtaaatcc catccctctt
    28741 tacctgttgt attaagacca agttgtgtta acattccttt aagaggatat ttagggtcat
    28801 aattagcacc tttacttatt gcatttgttt gcactctgcc atccattgtg cctatattag
    28861 tctgattacg ttcatttgca ctctgttttt tcaagctaga tgtttcatct tcttgatatg
    28921 gctctgccat tactgtcata ctcatcatca atataataat catggtaatc atagtagtta
    28981 atatattctt cttcatacta ctccccctta tttaattctt tttaaaacat aaaactatta
    29041 actcataaat atatggttat tagtaaattg aaattaagtc tggttcataa attattggtt
    29101 taatagaagt gtattgaaat tgtaccttta tattttcatt atataataaa cttatttttt
    29161 taaaacatat tgtttaaatc agtacattta tatgtttttt ttgttcatct gttttatcaa
    29221 atatattagt ctttgaattt tgtttgtatt cttcagcatt tttatctaac ttttctattc
    29281 tcgactcaag tttcattatt tcttcttgtg ttaaatttat aaaattttta agcatatttt
    29341 caagctcttc acgagtttta cctactaaag ataagtcctc agatactttc tcttttttat
    29401 tagaatcctc tttataatcc tttttttgtt ctaactcttc taatttttca tcatttaata
    29461 tttcttcttc aattttttca ttagactctt tagtgattaa agattctttt tcatcatttg
    29521 tatttagata agttgaattt tcatctaaca ttgtactttt atttttctct tctataatgc
    29581 tatttttaat acctatttct atattagaaa aattattagt tgtttctctt atttctgatt
    29641 tacataagtt cttaattgcg tcatttattt ttttagtata aacctcttgt ctatatttta
    29701 aatctctaat tctatcatta agttcttgct tttgtttcat aatattagat aaataagtgt
    29761 cttttcctac agtttcattt ttcttaacca tactttcatt tattcttgta ttatttatat
    29821 tactttcata tctaaatgaa tattgacttc tatattgact agatattttc atttatttca
    29881 cctccttaaa ataaatttat gtttataaaa accaacttaa cttaattata ttttatcatc
    29941 aaaagtatac atttacaaat attagttaat agttttatag gttcgagcat tattttcaac
    30001 aaaaaatttt tattataaat taaaacaata atttttataa atatattatt tgtattttat
    30061 aattcatata tttttacttt ataaattagc aatattgcag ttttgctctt aagaaacatc
    30121 tctatcatac ataagcatat actctattat gtattagtat aaatatgcct tttcttatct
    30181 tacataagac ctctttataa aggagcctat cgtaacaaat atgtatacat tatcacatgt
    30241 atatatcatc atataaaaaa tcaaacttta ttaaaaaaat taataaattg ctttaaataa
    30301 taccacaaac caaatttgcc atcaaaatca cattaaagta acaaattgat ggcaaattta
    30361 atatattaat agtatataga ctcatagaat gaacaaaaaa actacactta tcttctaatc
    30421 ttcttattta tttttgagat atttttaaat ttcttttctt tttttgctaa gtattcgctt
    30481 ttattgtctg caaatactgc ttcagtttta agcctacgat aggattccca tcttttaggc
    30541 gaaagttctt gatgagcaat agcttcccag atagcacagc ctggttctga ggtgtgagta
    30601 caattacgaa aatgacattt tccgaaataa gcttctatat ctgcaaaact tttatctaaa
    30661 ccttctgaaa catcccacat tcccaactct ctcatacctg gtgtgtcaat aacaatacca
    30721 ccacctgaaa ttaaaaatag ctctcgtcta gtcgtggcat gtcttccttt atcatcatct
    30781 atgcgaattt cctttgtatt taaaaattct ccacccatca gacaattaat taatgaagat
    30841 tttccaactc ctgaagaacc aagtaaggca acagtacagc ctggtttaat atacttagaa
    30901 atctgtttat aaccatctgg ctctatagat gaggtaacaa ctacatctac acccaaggct
    30961 atagaattaa ctacttgtaa tttacgatgc acattgtcac ataagtctga tttagtaagt
    31021 actactactg ggatagctcc actttcccat gttaaagaca gatacctctc caatctatga
    31081 atgttaaaat ccttattcag tgacatgcac aaaaaaacaa tgtcaatatt agctgcaacc
    31141 acctgctcct catttacctt tccagcagcc ttacgcacaa acaagctttt tctatgaagc
    31201 acatgatgaa taatagcatt accattttta ttattgcaac gatccaacat aacgaaatca
    31261 ccaactgtgg gaaaatcaga ttgtatagta gcctcaaaac gcagctttcc tgaaacctct
    31321 gcaaacagta caccatttac acatacagct tgataaaagt tcttttcctg cgagataatc
    31381 cgagcaaggt ataaatcatg atattccata ctttgagtaa taaaatttct atttagacca
    31441 tagtcttgta aattgatttg tttcatacca ttcattctgt ttcctccttt tccaactttt
    31501 caatgattct ttctagtggg aaagggggct gtgccagtgg ttttaatgca attgacatta
    31561 atttcactga attatcatca gctgcaatac gattagaact aagatgtcca cagcgtgtac
    31621 aacgatgaat aattgcccac tcaccatttt ttctcaccca cactccaata ggttccatat
    31681 tagcatcaca atctgcagca cggtcaccag gaatgatatc tacatgaaga ctatgtaaac
    31741 aatgtggaca atgatttcta tgttgtgtac cagctccttc aggaactaca aggcaaccac
    31801 aatttttgca aataaagtta tccatacagg aattttcctg ataataagct cgttttctat
    31861 ttttataatt catttttatt tcctccgtat cgtgtatttt ctacaaaaaa agtccacagg
    31921 tatttatatc tgccttttta tgtggtatac atatttacct acacaaaaac agaaaacccc
    31981 tgtggactag aaaatttagt atcttctatt tcaacataat tatattcaaa ataatactgt
    32041 gtaaaattaa taaaagtgta gcagattaaa gcccactaca ccacaattta acaaagtaat
    32101 atgtaatatt attatttgtt gtctaatgtt agttatctat aaaggcagag taagacacaa
    32161 caatcaaatg tatcaaaaat acacttaaaa attctgatta aacagaaccc atatgcgtct
    32221 ccaactattt atttgttggt taccattata tataactctg acatcaggca agacactcct
    32281 tcactaataa ttattattga aattttatca taaaatataa gtatgttcaa gtataattta
    32341 atatattcat atatttatgt ttgtctcatt ttcttattct ataaaatcta gtggtatttt
    32401 gaaatttaat gttcacctag tattaataat aaaaattaac tgctattatt tgttttctca
    32461 ttttatgcct gttgctcaat ttatctcact taaattaata acaactgtct tttcatacaa
    32521 aacctacaat caagtttttc catatattct acatgcatag tctatttttt ttgatataaa
    32581 ataacgttca tatttgtaaa tttatttaat tttcaaataa gtatattgaa taataagcaa
    32641 ttctattgta ttattgtaat tgtagaataa aactaaatcg gcaaaactag agaaatttag
    32701 tgacgcaaag ctatagggac taacgcttat aaaataaact atgagttatg tcagccagtt
    32761 gccaaaaaga gatattcttt ttgtttttat gaaagttttt tagggggata ataatatata
    32821 tgtttagaga taaaatggat agatgtacac atatgttgac tgcttatatt ggtagttcat
    32881 atgattattg tgattttata gatacacaac tagatgattt tatactagag tacggagaaa
    32941 atgtggtaga atcttgtttg catcaagtga tggtattagt aagtaagtat aattaaatag
    33001 atttggtttt ctagagaacc ctttttagtt ttatctactt taaatagcct tatgttagaa
    33061 agctaattaa gatagatttc tagtattcat aattttattt tttatttaaa atacatataa
    33121 taaagatgta aatttgtatc aaataataaa tatgagaact taaattctct tatctatgtg
    33181 aaaataaaca tctcttaaaa tgaaattctg taaatataaa tgatttttta gtttgaagga
    33241 ttagattaac aaaattataa atttgcaaat aagctatatt aaaaaatata ataatttttt
    33301 atataactta ttcttttata acttttaatt ttaaaagagg agaatgtata taagagtatt
    33361 caatgtacta gaaaaaatca aaagaaatat tagaagaaat ggatattgag taatcaaaga
    33421 aaagattttg atattacaaa tgatatgttt caagaaagca ttcctatcac aacaaaaatt
    33481 attcttgaag acatgccttc aaatgatgaa ttaaatcatg ttttttcaaa aggttgtgaa
    33541 cgaaaaatga aaaagagaaa aattgtatta atcacactac tattaatagg tgttttgtta
    33601 ttaggaagta tcctatataa tcttttttta ggaaaaacag ctaatatttc aatgctaaag
    33661 gaatcttgga attttgatat accaatacct aacaaagaaa ttgaagtatt tgatactcaa
    33721 gatagtatta atggagatgg acaaagttat tttattcaag gattttctga aaaaaatttc
    33781 aaaaaagttt ttaatttaaa aggtggtata gttgtaagca aagataatat taatgaaata
    33841 gaaaaatata ttgataaatt taaaagagat tctgttaaca ttaataaaag taataaaaat
    33901 aaaattgaag aagattttaa aaaatataag ttagaagtta aaaaagatga taagtatata
    33961 tataagagaa attatgagaa ctacgtagtt ttaattataa aaaaagatga acaaaaatta
    34021 tacagtttaa tatggaatca gtaggtacat atgtattatt aagaattata aataataaaa
    34081 ataaatttta gtcaatatac aaaaaccttt taaattgtct ggaaatcacc tcttcatttg
    34141 ttataaaaac atacaacaaa tgaagaggtg attttatggt tttaaaaaaa ataattataa
    34201 gtggatatgt gctttcacat gtttatcaac atttgtaatg cctatatttg ctaatgaatt
    34261 ataaaaatat taaataatat tcaactatag attatgtaaa ttactctatg aaaaaaatga
    34321 gttgtataaa atctggctac tgtagattga ctatttcttt taaaattaca attataataa
    34381 gttttataga attaaaaata aaactttaga gatttttgat aacattgtag actaaatttg
    34441 ccaccgaaat cgctttacag tggcaaatcg gtggcaaata caatatatta ttagtatata
    34501 atctatataa acattactat tgtttgatta tcttagctac agtttccaca tgtgtagaat
    34561 gagggaacat atctacaggt tgtgcctcaa cacatttaaa tccgtgaaca tttagataat
    34621 ctaaatccct tgctaaagta gaaggattac aagaaacata gacaattctt tccggattca
    34681 ttgaaacaat agtctctaat accttttcgt cacatccctt tctaggtggg tctacaacga
    34741 ctacattggc agtcttaccc tctctataca tcttaggtac aatttcctct gcctttccaa
    34801 cataaaattc agcattatgt atattgttta atttagcatt tatcttagca tcttttatgg
    34861 catcatctat aatttctatt ccataaacct ttttagcctt ttgtgccaaa aataaagata
    34921 ttgtacctat cccacagtaa atatcaaaaa cagtatcagt atcatttaaa tttgcatatt
    34981 caagagcctt atcatacaat actttagttt ggacagggtt tacttggaaa aatgataatg
    35041 gtgaaatctc aaacactaag tctcctatat aatcgtttat ttttccatct ccatatataa
    35101 ctatattttc tcttcctaga atagcattcg tatctttttg atttacattt acaaccaaag
    35161 tcttaaatcc aggtatattt tccttaagca ctgaagctaa ttctttaaga tatggaagtt
    35221 tgtttccatt tgctactaat acaaccatta cttctttagt tgtaaaacct atttttgtta
    35281 ctaaatgcct aatcaacccc gtgtgagtct tttcatcata tatgcttacc ttataggccc
    35341 ttatatatgt ttttattatt ttaacaattt tatcatttat ctcatgttgt attacgcatt
    35401 tttctgtcga tattacatca tgagtcttct ttttatagaa gccaataatt ggaataccat
    35461 tattcttttg tattggaaat tgtgctttat ttctatatct atatggatta tccattccta
    35521 tagtgtcatg aacttctaca tcctctaact tacctattct cgaaagtact tgtttaactt
    35581 catttgtttt catttcaagt tgtttattat aatctaagtc ttgtatctga caccctccac
    35641 aatccctaag attgtcacta cacactcttt tcaccctgaa tggagacttt tctattatct
    35701 caacaatatc tcccacagca taatttttct ttactttatt aatcctaact ttaactttat
    35761 catgtattaa tccgccctct acaaaaactg taataccatt gtactttcct actcctactc
    35821 cgccttgacc aatgtctact atatctacaa tatacatctc gtttttcgaa agcataaatc
    35881 accctccaat caatctatta tatttaaatc tttacaaact tttttcttta aatttatatt
    35941 aaaatattgc tattaattaa actatatttt ttactaagct acaatatttt attttaccaa
    36001 aaaaaaagga gcttataaag ccccttagta aataaattta ttatttttct tataaaactc
    36061 tagttgaacc tctatatacc acgcctcttg atgcatccac agttacaact tctccatctt
    36121 ttactagatt tgttatatca gctgcagaca caataactgg tatatctaaa tttataccta
    36181 caatagctgt atgtgatgtc attccaccat tctcagttac tacagctcct gctttttcta
    36241 tataattgtt catttcagca tcagtagcag tagaaacaag tatgtcgcct tcattaaagt
    36301 ctacacaagc atttccattc tttattatac gaactttacc ttctactgtt tgagtaccta
    36361 cacctatacc ttgcacgatt tcttcgctta ttacatgaac ctttattaaa ttagtagttc
    36421 cacttactcc tactggtact ccagcagtta taactactaa ttccccatta tctatataat
    36481 cagcttgtct agctgcctca attgcctttt ctataacttc atctgtattt cctgcaacag
    36541 aagacttaac tggatatact ccccatgtaa gagctaattt attcatagtc ttttcattat
    36601 ttgtagtagc tattattgga gattttggtc tgaatttaga taccattcta gcagtatatc
    36661 ctgaagaagt agatgttatt atagctgatg catttaaatc tactgctgtt gtacaagttg
    36721 catggcttat tgcatctgtt acagtaacat tgttagtacc attttccttt agtaatctat
    36781 cataatctaa agtctcttct gttctttttg ctattgtagc catcattttt actgcctcta
    36841 caggatattt tccagcagca gtttctccag ataacattat cgcatctgtt ccatcatata
    36901 tagcattggc aacgtctgta acttctgctc ttgttggtct tggatttctt atcatagaat
    36961 caagcatttg agtggcagta acaactggct ttgctaattc attacatttt tttatcatca
    37021 ttttttgaac tattggcatc tcttcagttg gtatctcaac acctaagtca cctctagcca
    37081 ccattatacc atcagaaact tttaatattt catctaggtt ctctacacct tcttggtttt
    37141 ctattttaga tattatttgt atatcagttg cattattgtt ctctaatact tctcttattg
    37201 ctagtacatc agatgccttt cttacaaaag aagcagctat ataatctatt ccttgactta
    37261 ttccaaactc tatatcactt atatctttag gagttattgc tggtaaattt atcttaacac
    37321 caggtacatt tactccttta tgatttttaa ctattcctga attttcaaca acacaaacta
    37381 tatcttctcc atttatttct tttactctta agccaactaa accatcatct attagtatag
    37441 aatctcctga tttaacgtct tcagcaagac ctttatagct tactgtacac atttctttag
    37501 tccccataat atctttcata gttatagtga acttttgccc ttcttctaaa aatacctctg
    37561 ggtcttcaaa gttacctgtt ctaatttctg gacctttagt atctaataat atagcaactg
    37621 gcttatttaa tttttctcta actttctttg ccatatcaat tctttcttta tgttcttcat
    37681 gcgaaccgtg agaaaagtta aatctacaca catttagacc attttgcata agttgagtta
    37741 aaacttcctc actttgtgat gctggaccta gtgtacaaac aatttttgtc ttctttacat
    37801 tatttaacat atttgctcct cctgagatat tattccacag atttattttt aatactaaaa
    37861 cttatataga taatattttt gccatctcat aagcttcttt atcaaatact ttcttttgag
    37921 ctaaagcttc acttatttct aaatcaatta ttttgttttc ttttattcct acaactctag
    37981 ctgattttcc atctaataat aattctactg ctcttactcc aagtctactt gctagtattc
    38041 tatcagatac agttgggctt cctcctcttt ggacatgccc caatacagtg actcttaaat
    38101 ctgctcctga ctctttttta agttcctttt ctaaatcact agcacttccg actccttctg
    38161 ctaaaacgat tatactatgt ctcttacctc ttttttgagt agtctttaat cttagagcaa
    38221 cttcatctac tgtaatttct acttctggta ctattatagt ttccgctcct cctgcaagac
    38281 ctgcatataa ggctaaatct ccacagtgtc ttcccataac ttctactatg ttaactcttt
    38341 catgagatga tgatgtatct cttatcttac ctatagcatc tataatagta ttcattgcag
    38401 tatcaaatcc tatagtataa tctgtatatg ctaaatcgtt atctatagtt cctggtatgc
    38461 ctatagctgg gaatcctaag tcactaagtt tttgggctcc tgcaaatgaa ccatctccac
    38521 caattacaac taagcaatca attttatact ttttaagaat ttttactgct tttaatctac
    38581 cttcttctgt tttaaattct tcacatctgg aagattttaa tatagttcct cccctgtgta
    38641 taatatctcc aacagaagat aagttcattt cagttaaatc ttcttctagt aatcccttat
    38701 atcctctatt gattccatat actttgcatc cataatatat tgctgatctt acaaccgctc
    38761 taatcgcagc attcattcct ggagcatctc ctccacttgt tagtaatcct atagttttca
    38821 ttttttacct ccttggattt tatgtcaatt ttttattata atcattgtta ttgtattcta
    38881 atggactttt tttgtcccta tatcactttt taatcccatc aagactaaaa aaattaaatg
    38941 tccttaaatg tccattttgt gatattatat cacaaaacgg acaatatttt tcatattatt
    39001 ataatatatt tagattttta tataaaaaat caagctttta cttttatgtt atctttagga
    39061 agtaactctt ctaagttatt tataaattca tcacatatac aagtcaatgc cccggtcatt
    39121 ttatatgctt tacgtttacc atttatattt tcatccatag ggtataagta tatactgtca
    39181 ttacctggat attgtttggc tatttctaca atattattag ttgtatcagt atcagacata
    39241 ctatctattt tcaaatacaa ttttttacca ctttctggct taatattttc tacatttcta
    39301 gttcttcctg aattgtagtt tctatctgca aagtcagtat catcatttat atcttttatc
    39361 tctctagcta taagttttgc attttcgcct tcttttatac ttaatgttcc ttttacatat
    39421 attatattat cttcattcaa aatgacatta tacttttgta ataattgagg aaaaactatt
    39481 atttctatag caccatacaa atcttctaat tcaataaatg ccataatttc atttcgtttt
    39541 gttgttttaa tagttttagt tacaatcatt ccacccatta taacatctgt ttcattcatt
    39601 tgtaggtatg actcttcttc ctcttttaat gaatttaatt ttccattatc catagatgtt
    39661 ttttcttgta gttctttttc aaattgtgat aaaggatgtc cacttacata cattcccaag
    39721 acttcttttt caaggttaag tctctctctt tcttcgtact cttgcctttt aggcaaactg
    39781 tatatttgtt gaaaatcact atcttcctca ctatctccaa aagcatcaaa taaagaaatt
    39841 tgaccttgaa catttttctt tctatccata gatacacttt ctaataaact ttcataacca
    39901 gccatcagac tagctctatt ttcacttata ttatcaaaag ctccacattt tattagactt
    39961 tctattactc tcttatttgt atctttttgg tctaatcttt tgactaaatc tactaaatct
    40021 acaaataatc cattagattc tctttcagcg attatattgt ttattatatt tacgccaaca
    40081 ttttttacgg ctgctagacc aaatcttata ttgtcgcctt caactgaaaa ctttgaaaaa
    40141 cttttgttta tatctggagg taatacatct atttctagtg ctttacattc tcttatatac
    40201 tcaactacct tatcagtatt tcccattaca ctggttatca atgctgccat aaattcaact
    40261 ggataatatg tttttagata agctgtctca tatgctaaaa ccccatatgc agctgcatgt
    40321 gatttattaa atgcatatct agcgaagtct atcatatcat caaatatttt attagctatt
    40381 tcctcttcta caccatttct gatacaccct gcaatttcta tattaccatc ttcatcaaat
    40441 ttaccatgaa taaaatattg tctttcttct tccatcacgt ccatcttttt cttactcatg
    40501 gctcttctaa ctaggtcact tcgtccgtaa ctataaccac ctaaatctct aacgacctgc
    40561 ataacctgct cttgatatac caaacaacca tatgtaactt ccattatagg ctttaatttt
    40621 tcatgtagat atgttacatc ttttgggttg cttttatttt ttatatatgc aggtatagaa
    40681 tccattggac ctggtctaaa tagggatatt cccgctacaa tatcttcaaa attgtctggt
    40741 tttagctgtt tcataaaact tctcatgcca gcactctcca attgaaacac ccctagtgta
    40801 tttcctgatg aaagcatttc atatactttc gggtcgtcat aatccatctt tgaaaagtct
    40861 attttttctg tgtaattttt tataactcta tttttttcta ttaaatcaag agtatctctt
    40921 ataactgtaa gagttcttag cccaagaaaa tccatcttta aaagcccaag ttcttcaagt
    40981 gttgtcatag taaactgtgt tgtgattgca tcttgatgtt tgtacaaagg tacatattca
    41041 tctacgggat tttttgatat aacaactcct gctgcatgag tagaagcatg tcttagcatt
    41101 ccctctatct gttttgatat atttattatt tcttttgttt ccgggtcttg gtcatacaat
    41161 tctttaagat taggatttgt atctagggcc ttatctattg tcattcctaa agcaaatggt
    41221 atttccttgg ctaccttgtc aactttattg tagcctatat ccaataccct tccaacatct
    41281 cttattgcag cttttgcacc cattgttcca aaagttatta tctgggctac atggtcatca
    41341 ccatattttc tctttacata atctataact tcttctcttc tctcataaca aaaatctata
    41401 tctatatctg gcatggatat acgttctgga tttaaaaaac gctcaaataa tagagagtac
    41461 tttattgggt ctatatcagt tattttaagt gtatatgcta ctatcgaacc agccgcacta
    41521 cctctacctg gtcctactat aatattattt tctttagaaa aatttataaa atcccaaaca
    41581 attaaaaaat actctacata acccattttt tcaattacat ctaattcata atttaatctc
    41641 tctagtatct cattactagg attatcatat ctctctttta atccattaaa acacaactcc
    41701 cttaaataag tttctggtgt atatccttct ggaacatcat acttaggaag atgtatagta
    41761 ttaaaatcaa actccacatt acacatatca gctattttca cagtattgtc aatagcctct
    41821 aatgcatatg gaaataattc ttccatttct tctcttgatt ttaaataaaa ctcatcacta
    41881 ccaaatctca ttctatttgg gtcatttaat gtttttccca tttgaataca cataagtaca
    41941 tcatgtattt tcgaatcttc tttatttaca tagtgaacat cattagtagc aactagtggt
    42001 ataccagtct cttttgataa ttttactaaa ccagagttta cttctttttg ctcaggtaaa
    42061 ttgtgatctt gaatctccaa aaagaaattt tcttctccaa atatgtctct gtagtcaaga
    42121 gcaaattgtt ttgctttttc ataatttcta ttcattaaag cacgtgctac atctcctgca
    42181 aggcatgcag aaagtgctat aatccctttg ttatgttttt taagttcttc catgtcaact
    42241 ctaggcttat agtaaaaacc ttctacgtat gaagttgaaa ctatttttat taaattttta
    42301 tatccttcca tattcttagc taacagaact aaatgtcctt gatatttgtc atagtttggg
    42361 tctttatctc tcaatccacg tgcagctgta tagacttcac accctataat tggctttatt
    42421 ccttctttta tagctgtttt gtagaaatct ataacaccaa acatacaacc atggtcagtt
    42481 atagctattg agctcatgtt tagttcctta gcccttttta taagtttttt caccctcgaa
    42541 aacccatcaa gtaaactata ctcagtatgt acatgaagat gagcaaaatc tttgttcatt
    42601 aaatcacctc ctgctttata attttaattt taccacaaat atatgtccta aaacaaaaac
    42661 agagactttt atctcaaaat aggaattaac ttcaacgtat accattatat gttataaatt
    42721 aatgcttatt ctgagattgt cccctcaatt tattgctatg attttttttt caaatctgtt
    42781 gcaatttctt ctatttttct aagtctatga ttgactccag attttcctat tggtggttct
    42841 aacatctctc caagttcttt gagagtcata tcctcatact cgattctaat cttagctatc
    42901 tcttgtaaat tttctggcaa actgctaatt cctatagtct cttgtatgag cttaatattt
    42961 tctacttgtc ttactgctgc atttactgtt ttagaaaggt tagctgtctc acaatttact
    43021 atcctgttta cattatttct catttctttt actattttag tattttgaag acttaaaaga
    43081 gcgtggtgtc ctcctataat actcaacaaa tctgatattt gttcactctc tttgatataa
    43141 acaacgtgat tattttttct agccacaatt ttactattaa aacctaaaga gtttataagt
    43201 tcttttagag aatctgcaaa ctcctcatta ttagttacaa attccatatg atagttcttt
    43261 tctgggtcgc ttatagaacc tccaccaaga aaagctcctc ttatgaaagc tctcttacat
    43321 ccttcatgct taattaagtt ctctgaaatt ttgtttatag taaaaaatcc ttctttatct
    43381 tcaagtatac ctaacttttt taataacatt tctgaaccca tttcgcttgt taccattaat
    43441 acataactgt tatttctctt tagcatttga ttcttattta ctgagattgt agtattgata
    43501 ttaaaattct tttttaataa tttaaatact ttacgggcta ttgaatttaa ctctgttgtt
    43561 atctttagat ttagcttctt atatccaaca atttgtatac ttccccctga tttaactaga
    43621 gctgacaatt cagctatatt acaacattca ttcccagata taactcttgc tagttcattt
    43681 ttggtttcag ttgaaaaaga catatctatc acctattaac taatttttct ttaacctttt
    43741 ttttatttct tgtaaggcaa cctttattat ctccttttca tcatcatacc tagctaagtc
    43801 tactactcta tctaggtgga taaatttagc atcaataaag ccttcctctt tttgtggaat
    43861 agtatccata ttctttgctt gcatcaaata ccaaaaaact gttttatgaa ctgctctatt
    43921 ttcatcccag ttttctttga atgtatagtg tatttcacct aaatatttca atatatctgc
    43981 ttttactcca gtttcttcac ttacttcacg taatgctgcc tcttggttat tttccccttc
    44041 ttctactttt cccttgggta acacccaatc tccattgaac ttccttagta aaagaatcgt
    44101 attgccaaac aggactacac caccagcact aacctcttct ctcatcgatg ttcactcctt
    44161 aaaactaaca taatgataag gatttctaca caatttttta aaatcctttt ttactaactt
    44221 ttgttgtaat tatgatttag ggctaactca ataactatgt tagatatata ctttgcatca
    44281 tgtcttatat aattattttt tatttcaatt aaattcttct ctacagtttt tatacccatc
    44341 tcttttaatt tatctttttg ctttttatct aacaagactt gctctgctcc atcttgttta
    44401 tataagtcaa gcatttcttc tggcaatatc tcattatttg cgattacata atctattaaa
    44461 ttctcatcag tgtgttttac tatagcatta acatgctcta atacattgta cccttctgtc
    44521 tcacctggtt gagtcattat atttgctata tatacttttg gagctacaga cgatttaata
    44581 gcgtctacaa tcccctctac aagtaaattt ggtattatac ttgtatataa acttccagga
    44641 cccataatta taatgtcagc atcataaata gatgcaataa catcctttaa tggttttaca
    44701 tcttttggat ttaaaaaaat tttatcaata gagctttttt gaatttttga ctcttcaggt
    44761 atactagatt ctccatttat tatattgcca ttttctaatt tggcaactaa atttacatct
    44821 tccaaagtta ctggtaaaac tcttcctgtt atagcaaaaa tttcacttaa tttatataca
    44881 gctttttcaa agtttccata caacccattc atagcagcca aaaacaaatt tccaaaactc
    44941 tgacctttta aaagcccttc tgtaaaccta tattgcataa cttcattcat tgttggctct
    45001 atatttgcaa gtgctaataa acagtttctt atgtctcctg gtgggagcat tcctaagtct
    45061 tctctcaata cacctgaacc tccaccatca tcagcaacag ttacaattgc agttatattt
    45121 tgcgtagtgt gtttaagacc tcttaaaaat accgattgac cagtacctcc acctatcaca
    45181 accacatttg gttctctatt ttcaacaata gacctttgaa atagttttac tttttcattt
    45241 tttgcttttt tatatataaa taacgataca attaatgcaa tccaacctaa aattcctaca
    45301 ataataagta atttagccat gtttgcctcc attatcgcaa catagagtct ctatgtttct
    45361 ttacaactct atatccctta ttagataaat cctccgctat aagatttgtt atagtaactg
    45421 acctatgtct tccacctgtg catccaacac caattactag atgttgtttt ccttcctcta
    45481 tatattgagg tactaaaaaa tgaatcatat ctaaaagttt cacataaaat tcttcactga
    45541 ttttagaatt cataacataa tctctaactt ctttatcatc accagtttta gctcttaact
    45601 cttcaacata atagggattt ggaagaaatc ttacatcaaa tactaaatct gcatcagcaa
    45661 gtataccatg tttaaatcca aaagatacta cagaaatagt taggtttgga ttatcttcac
    45721 cagaagaata tattttcttt atttcttcct taaggtcttt aggtttcatg ttagttgtat
    45781 caattataca tgtagataac tcctttaaag gttccattat ctttctttcc atttttatac
    45841 cttctggaat ctgcatatct tttgccaatg gatgatttct tcttgtcatt ttatatctct
    45901 ttagcaatac atcatcatta caatccaaat ataccatttc atattcataa ttttcttttt
    45961 ctaaataatt taagctttca tgaagcgctt caaaaaactt tctccctctt atatctatcc
    46021 ctagagcaac tttatcaata cttgaatttg gttgataaca taattctgca aatttagtta
    46081 tcaaagcagg aggtagatta tctacacaat aaaatcccat atcctctaaa gctctcattg
    46141 tctcactttt tccagatcct gaaagacctg taactataac aaatttcatt gctaactcct
    46201 cccttttatc ttatgtttat tatattataa tgttttctac taacgatata tccagattag
    46261 agtcagatat agtcttcata gctagttcaa aatcaccaac tctttctgga caatgtgcat
    46321 ctgagcctat tataaattta ttttctagcc cttttatttt atttaattga tttacattca
    46381 aaaaagaatg gctactattt atctcaagtc tagtatttgt cttttttgct gtctttgcta
    46441 cttcttctat atacacatcg cctttatctc ctggatgagt aattataaaa atatcattat
    46501 tacttatcgc atttattaca gcttttgtat tatattcttt tgctttttca gttttaaaaa
    46561 tatagttatt acaatgattt aataagcttc ttaatgatgt tggagtagaa ccaaaatgat
    46621 atccagccat aatataatca aaatctctaa taaatttatc atccatatct atatttcctt
    46681 tatcatctaa tatgttacac tccataccta aaagtatatt tatatcagtg tacttatcat
    46741 ttaaataatc tacttcttct ctcattttga gaatatcttt tttctttaca ccatatgcaa
    46801 tatgtttata actatggtca gatattccta ttgtttttat tcctttagaa atggctacct
    46861 ttacattatc ctcaatagtc cctttgccat gactatataa tgtatgtgta tgataatcag
    46921 ccagtatttt catttgttaa tcctctccaa gtattttgac ttcttcttcc aacataaccc
    46981 caaacttggc atatacagca ctttttataa catatattaa atccaaaata tctttagcac
    47041 ttgcttctcc ttgattgact acaaatccac aatgcttctc agatacttgt gctcctctta
    47101 aagtaagacc tctcaatcca gtttcttcta ttaatttacc tgcaaaatat cctgttggtc
    47161 tcttaaatgt acttcctgca ctagcaaaat ttaatggctg tttagttatt cttctcgtcg
    47221 ctaaatcatc cattaaactt tttatttcat cataatttcc ttcttgtaat tctaattctg
    47281 ctgataaagc tatatatccg tttttcgata ttatactttt tctataccca aattccatct
    47341 gttcatttga taattcaaat atattgcctt ccatatccat cagtcttact gacttcacta
    47401 tatccttcat ttcaccacca tatgctccag cattcatggc taatgctcct cccaatgtgc
    47461 caggtattcc tgatgcaaac tcaaaccctt ttaattcttg cttttggaga gctttcccta
    47521 aaactgataa taaagctcct gactgagcag tcatcctagt atcatttatc tcataagaat
    47581 tgaaattatc agctaattct attaccactc ctcttattcc accatcttta attaaaatgt
    47641 ttgaaccatt tccaattatt aaatacggaa tagactcttt ttttaccaac ttaagtacat
    47701 tttttaattg ttcttcagtt ctaggtctaa ctaatatatc tgctggtcct cctaccctaa
    47761 atgaaatatg ttttttcata ggttcatcga cttttatatc ctctttactt aatatattta
    47821 ataaatttat atatatatct tgattattca ttgtatttcc tcccaaatta tactgaactt
    47881 tagctgtcat tattatttaa attacattaa tatatagtat taactatatt caataatata
    47941 tgattttgct tatcatatgg attttatatt ttaagcttct taattacaaa ctatattcaa
    48001 taaatatata ataaagtaaa aaaaaaaaaa taacaacata taaaagaata taaataattt
    48061 aaaaaaagca tcaatatcac tgatatcaat gctttaaaag gcaatttaat tcgtattatt
    48121 tatctaacta tttttgacat agcaaagata ataaatccct ccaactacta tggaacctcc
    48181 aacgatattt ccaagtgtta caaataccaa attagttata aattgaacca tagttatatt
    48241 tgctcctaat gccattccca ttggtataaa aaacatgttt gcaacactat gttggaatcc
    48301 acataataca aatagcatta ttactgtcca acatgaagcc aattttgaca ttatatcttg
    48361 agatgctgta gccatccata cagctaaaac gactagaata ttacaaagta ttgcttttaa
    48421 aaacattgat gctatagttg aattaacctt agcttctgcc acagctatag cttttgtagc
    48481 tgcatctcct gtcaatgtag aagaataaaa cacaagtgca actagcaaaa ttgaacctac
    48541 taaatttgca aaataaacca gtccccagtt tcttaacatt tttcctaatg ttattttttt
    48601 gtccataagt gcaatagcca ttaaagtgtt tccagtgaat aattctgctc ctgccactac
    48661 tacaagcata agacctactg gaaagaccat agcacttaaa aagctagcta cccctgggtc
    48721 tatcttgcca aaagtttgac taactatcat actccccaat gccccaaaac ctataaatgc
    48781 tcctccaaat aaacctaata gaattgcatt ttgtgtcgaa atatttgctt ttttaatgcc
    48841 tgcacttata gttgcttgtg cagtttcccc aggtgtcaag aatcctttac tcataaatcc
    48901 ttccccctta aaaattatac tttcccttgt ctttttatgg caataattat ataataacaa
    48961 tatgatatat aataaatttt attaacataa aaaatatact atatacttat atatacttgt
    49021 ctcatataat tatactattt attatataac aactttgtta atttcgaaat aatttatatt
    49081 gaatttgaaa aatttacctt ttgattattt attttacttt ttaattattg aggtattata
    49141 tataatagat atatgtttgt gttattatat ataattactt attttaataa atatttgaag
    49201 gagggaattt tatgtttgat atatcatttt tcgaaatgtc aatatatgaa atagcagtta
    49261 ctacaatata tataattaat ttcatggtta tactaaacct tatctttaga gaaaaaagaa
    49321 acataaatac aactttaaca tggcttctta tattagtatt gattcctgct cttggattca
    49381 tactttatat agcttttggc agaaatattt caaaaaacaa tatgtttaga ttgaaagaaa
    49441 aggatgataa gataatcaaa agtaatatac tagatactca ggttaaactc caatctacat
    49501 ctgaaattga ttcagatata catcaacata aggatatgat ttatgcattg gctaattcaa
    49561 ataatgctca ttataccaat aataacgatg tgtggattta tgctgaatct agtcaatttt
    49621 ttaacagtct tcttgaagaa cttaaaaaag ctaaaaaata tataaacata caattttaca
    49681 ttttcaaaga tgacaaaatc ggaactgaaa taatagacat tcttatagac aaagctaaag
    49741 aaggtgttga agtaagactt ttatttgatg cagttggtgg tagaacacta aaaaatagta
    49801 cactttccag acttaaagaa agtggtgtta aagttggaag cttcttccca tcattcttga
    49861 aaattgtaaa ctttaactta aactatagaa atcaccgaaa aattgttgtc attgatggta
    49921 aggtaggatt tgtaggtgga tataatgttg gtgatgaata tttaggtaga aatccaaaat
    49981 ttggtctatg gagagataca catactaagc ttactggtga ttgcgtaatt gacctaaata
    50041 tgagattcat ccttgattgg agatatacaa ctaaagaaga cttagattta gaaaaatact
    50101 ttatagaaga agatacaaat tctaatcatc cttctgaaaa tattgggatt cagatagtat
    50161 caagtggtcc agatatatca gaacttgatg agattaaata tggttacctt aaaatgattc
    50221 agaaagctag aaagtatata tacatacaga gtccttattt aatacttgac tcaactttta
    50281 tagatacttt aaaaatagcc tgtttatctg gtgttgatgt gagagtgatg attccttcta
    50341 aacctgacca tccctttgta tactgggcat catattcata tgctggagaa cttttaaagt
    50401 ttggagctaa aatctatact tatggtcaaa atgcattttt acatgctaag acaatagtta
    50461 tagatgactc tatatgctct ataggaacag ctaatatgga tatcagaagt tttgagctta
    50521 atttcgaagt taatgcattt atgtactctt caaaaaaagc attggaacaa agaattatat
    50581 ttgaaaatga tattttaaat tctaaggaaa taacattaga tatatataat tctaggtcta
    50641 cttatataaa aatcaaggaa tcaatttcaa gactattatc agcagtttta taaatctttt
    50701 attttataaa aattttacat tttggtttat tttttaaagt tttttatatg tattattttt
    50761 tttttattga atttagctca ttttttttat tttttttaac tattctgaat tattttatat
    50821 tataatagac tagtatagtt tttattttta ataggtaact tttttgcatt gtttttataa
    50881 ataaagaaat tgttgtatat tattctttct ttattgtttt ggttttgttc acccacataa
    50941 tgttggggtc aactcatggt taattatttt atgaaaaata ataactttaa aaagaaaagg
    51001 gggatttgtt atgtgcgatt ttatttcaca caacaagcaa ttatttgacg aactagatat
    51061 atttattgac tctcttgcaa caaaggaagg tgcgttaata caagttctac atgaagccca
    51121 aggtatattt ggatatcttc caaaagaagt tcaacttcat gttgctagaa aacttggagt
    51181 agctcctgca aaggtatatg gggttgttac attctattct tattttacta cagaacctgt
    51241 aggtaagtat aaaatcagtg tctgtctagg aactgtatgt tttgtaaaag gtgctgacaa
    51301 aatcttaagt gcttttgaaa aacagcttgg cataaaagtt ggagaaacta ctagtgattt
    51361 taaattttct ttagaaggtt taagatgttt gggggcatgt ggtttagctc cagttgttac
    51421 tgtaaatggt aaagtttatg gtaaagtgaa acctgaccaa gtaagcgaaa tattagatac
    51481 ttatagagaa ttagaattga attgttaaga ggggtgaata aataatgcgt aaagtaaatt
    51541 catttgatga attaaaagtt ttagctgatg agctgaaacc taatcttagc ttaagaaaaa
    51601 attattctaa ggaaaatgta ttaagaagag aattacttgt ttgttgtgat actggatgta
    51661 catcttcaaa cagtctagaa atagttagtg aattagaaaa tgaaataaag aaatcaggaa
    51721 tccaagataa agttagtgtt cgtttgacag gttgttttgg tttctgtgct caaggtccta
    51781 ttgtaaaagt ttatcctgat aacgttttct acgtaaaagt tgagccatct gatgctgaaa
    51841 agatagttca aagccactta attagaaata cagttgtcga ggaattatta tatgaggaag
    51901 aatctttaag taaaaaagtt gaagaacaag aagaaatgtc tttctacaaa aaacagttac
    51961 gtatagcttt aaaaaattgt ggtcttatag acccagatag tatagaagaa tatattgcca
    52021 atgatggtta tttagctcta ggcaaatgtt taacttctct tactcctcaa gaagttattg
    52081 cagaggtaaa aacttctggc cttcgtggta gaggtggtgc aggtttccct actggctcta
    52141 aatgggaagc tgcttcaaaa aatccagctg gtccaacaga taaaaagttt gttgtatgta
    52201 atgctgatga aggtgaccca ggtgcattta tggatagatc tgtacttgaa ggtgaccctc
    52261 atagtgtact agaagctatg gcaatatgtg gatacgctat aggttctgat acaggataca
    52321 tatacataag agcagaatat ccaaaatcta tagaaagatt aaaagtagcc atagctcaag
    52381 ctgaaaaata cggtttactt ggcgaaaata tcttaggcac tggatttaac tttaaattag
    52441 aattaaaata tggtgcaggt gctttcgttt gtggtgaagg tacagcgcta atgcattcaa
    52501 ttgaaggtag acgtggtgaa cctagaatga aaacttatag ttcttctaag agtggtctat
    52561 ggaaatctcc tacttgctta aataacgttg agacttttgc taacatacct gcaattatac
    52621 ttaagggtgg agattggttt gccaacttag gtactgaaga ttctagtggt actaaagtct
    52681 ttgctcttgg tggaaaggta gaaaatgtag gacttgttga agttccaatg ggtactactt
    52741 taagagatat tgtatttgaa attggtgggg gaatccctga aggtaagaaa tttaaggctg
    52801 ttcaaacagg tggaccatct ggtggatgta taccaactga acatttagac actcctatag
    52861 actttggttc attaagttct atcggttcaa tgatgggctc tggtggtatg cttgttcttg
    52921 atgaatctga ctgtatggta gatatagcca agttcttcct tgagtttact gttgaagaat
    52981 cttgtggtaa atgtacacct tgtcgtatag gtactacaag attattagaa atattaacta
    53041 aaattacaga aggtaatggt actctacaag atttagatga cctagaaaac cttgctgaaa
    53101 ctatacaaac tgcttcatta tgtggtcttg gtaaagctgc tccaaaccct gttttaagta
    53161 ctcttcaata tttcaaagat gagtatatag ctcatgttgt agataagaaa tgtcctgctg
    53221 gtaaatgtca gaacttactt tcttacttta taacagatga ctgtaagggt tgtacaaaat
    53281 gttctagagt gtgtcctgct ggttgtataa caggttctgt taaggaacaa catacaatag
    53341 atacttctaa gtgtctaaaa tgtggtgctt gtatagataa ttgtacattt aacgctataa
    53401 tcaagaaata acttatttgg aggaggaata acaatgagtt tagttaattt aactattaat
    53461 ggcaaacacg tttcagcacc tagtggaact tctatcttag atgctgcgaa attaataaat
    53521 ataaaaatac acaacctttg tcatttacat atgaatgaaa tagataagct tgacacttgt
    53581 gcttcttgtc gtgtttgtat ggttgagaca gagagaggat tagttccagc ttgtggaaca
    53641 gttataaagg aaggtatgaa agttcagact aatagtgcta aagcattaaa tgctcgtaga
    53701 actattgttg aattattgtt atcagaccat ccacaagatt gttttgtctg tgaaaaaaat
    53761 ggagattgtg aattacagac tatagctgct gatttaggag taagaaaaat aagatatcaa
    53821 ggttctaaat cttttgcagg taaagatact tctactaaat ctttagttaa agaccattct
    53881 aagtgtatat tatgtagaag atgtgagact gtatgtaatg acatacaaac agtaggagca
    53941 ttatctggag ttaatcgtgg atttaatact ttagttagta cattctttaa ctctgatatg
    54001 gttgaaacag agtgtacatt ctgtggtcaa tgtatatctg tctgtccaac tggagcatta
    54061 acagaagtag ataatgtacc taaactttgg gatgttttaa ataaaaaaga aaagactata
    54121 gtagtgcaag ttgctcctgc tgtaagagtt gctattggtg aagagtttgg attagaacca
    54181 gggtcaatct ctacagggaa aatggtagct gctttaaaag cacttggatt tgaacatgta
    54241 tttgatacaa actttggtgc agattttact ataatggaag aagctactga atttatagaa
    54301 agaatccaaa aaggtgaaaa tcttcctata ttaacaagtt gttgtcctgc atgggtaaac
    54361 ttcttagagc acaattatcc agacaagtta aacttagcat ctagctgtaa gtctcctcaa
    54421 ggtatgtttg gttctatagc taaaaactac tatgcaccta aaatattagg aatcaatcct
    54481 gaagaacttt atgttgtatc tgtaatgcct tgtgtagcta aaaaatatga agcttcaaga
    54541 gaagaattaa gtgaatctgg aatactagat gttgaccttt ctataactac tagagagtta
    54601 gctaagatga taaaagaagc tgcaatcgat ttacctaatc ttcaagacca agattttgat
    54661 aatcctctag gaaaatctac aggtgctgca tctatatttg gagcaagtgg tggagtttta
    54721 gaagctgccc tacgtacttc atatgagaag ataactaata agactttaga taatgtaaac
    54781 ttcactaatg ttagaggtct taaaggaatt agggaagcaa gtatagatgt tgatggaact
    54841 acagttaatg tatgtattgt aaatacactt aaaaacgcta gaaagattat ggataaggtc
    54901 agaagtggag aatgtaaata ccatatcata gaagttatgg catgtcctgg tggatgtgtt
    54961 ggaggtgctg gtcaacctta tcaccatggt aatactgaaa tagttgatag acgtgcaaat
    55021 gcgttatatg aaatagatag aaataaggct attcgtaaat ctcatgagaa tcctgattta
    55081 caagctattt ataaagactt ctttggagaa ccaaatagtg atgtagctca taaatacctt
    55141 catactcatt actttgataa gagttgtgtc tatggagagt gtccacaaga atgtgcttgt
    55201 gaagaagcta agtagtcata acaaagtata aaatttattc ttaaaaaagg attgtcttaa
    55261 aatactttta cgtaatttaa gacaatcctt attaatttca caaattaaat tatatttcta
    55321 aatagactta tttattaatt aacctatcta ttaattaaag aatacctgcc attctcataa
    55381 gttgttttgc atttgtagtt ttacatcttc catcttttat cttatagtca aaatgaattt
    55441 tatcgtctac atagtactct gagaaatgat agtttacaac ttcaacatct ccgctacctg
    55501 aaaggtcaca tagctcaaag tcatgtgttg tcaccatact tataacccag ggttttgata
    55561 atttctttac tgcctcactt gctccaataa ttctatcagc agagttagtt cccttaaaaa
    55621 tttcatctac tagaaccaac attggcagtt cttttaaact atattgaatc attgatttta
    55681 ttctaagaat ctcagcatag aaagttgata ttccttgact tacatcatct tgtattctca
    55741 tagaagtaaa tatagccata caggtcgcat caaaactctt agcgcatact ggagcacctg
    55801 catatgccag cactaagttt acaccgatac ttcttaaaaa tgttgtcttt ccagacatat
    55861 ttgaacctgt gataatacaa gtctgagaat ttaattgtat cgaatttgct atgacacttt
    55921 tttctgctat taatgggtgg tatacctctt caactttcaa tcttggagta tcttcatatt
    55981 ttattactgg aaaacatgta ttttccttta catgagaaac aactgttaaa cttattagag
    56041 cttcaaattc tccaatagat tcaaaccaat ctctaatttg atttccatat atacctttcc
    56101 atcgctccaa agcttctgca caatgatagt tccacatcaa aacaccacgg gcaattatat
    56161 atagtatctg attatacctt aggtttacag catttcctat tgaatttaat tgtttaacac
    56221 ctcttgaaac tccacttccc ttagaaagtt tatcttgtaa ttctttcaaa tatgcactct
    56281 caaacgtctc tttttctaaa acctcaaaca ttttttcata tacttgtata cttctactaa
    56341 atgaaaataa tggagcaaga gtttgcataa gtcttggata tccaaaacca ctaaacccta
    56401 actggattat aaaaagtaaa aaaacaggta aaacaggtaa aaatcctaac atacaaaata
    56461 taaaagataa gattgttgca gttggtaaac cccaagtaaa aatatgcatc cattttggta
    56521 tatacacatt cttattttct ccatattcta taaacgattc tatactacta tctgaattgt
    56581 ttttttgctc tttaccaatt atattactga gtgtttgaat atgaatagaa aaatcatctt
    56641 ttgataaaag ttcttttata gctctctgtc tttctaaaat tatattctca tctggatttt
    56701 cattccacaa atatttggct aaaaaatttt tcccataaga tgtattagct acacagatat
    56761 attgatacaa tgatgctctt ccaaataagt ctaaatcttt tgcttgcgaa ttttcatctt
    56821 ttaagtattc tttaccatct attttaaatt ccttccaacc atctccaaat ctcttaatat
    56881 acttatttaa tacttcgctc ttacttttaa aatatgtttc ttcttctttt actttactat
    56941 gaataactaa gagtgctata aatattatta ttgataaaac tccaacaaaa atacctacta
    57001 tatttttatt ataaaatcca atagcaagcc ctgctatcac tatcaaaaaa gatattaatc
    57061 ttgctgtact tatgttattt gactttttac ttaagagcaa ttctttttca gtactacttt
    57121 ctaaaagttt actaaaatat tctattccca taaaaaattc caactttctt gttatataat
    57181 gaaactcaaa tataaaatta atctagtatt attataatct aacactgtac tttaaattat
    57241 ccttatataa tatatcttat taataaacat tatatataca acttgatttt aatttataag
    57301 gtgtaggaca taatcctaat caatatttaa ttaaatgatg tgtagtccac tattattcag
    57361 tactacttag tatcgattaa ttttgataat tttttagtaa attcttgagc tgcatcgtat
    57421 cccattcctc tttgtctaaa attcattgct gctacttcta atatcatagc agtatttctt
    57481 ccaggtttaa caggtacaac taatttctct acattaacac caagtatttc ttcatattct
    57541 ttatccagtc ctagtctatc ataatactta gtttcatccc aagcttctaa atgaactact
    57601 aaatctatca ttttagaatt tttgattgcc cctactccat ataaacttct aacatctatt
    57661 attcctattc ctcttatctc aagaaaatgt cttattagtt caggtgactg acccacaagc
    57721 atactttcat ctaattttct tatttctaca gcatcatctg caactaatct attacccctt
    57781 tgaatcagtt ctaatgctgt ttccgacttt cctatactac tttcaccttt tatcagtaca
    57841 cctataccat aaatatctac tagcacaccg tgaattgttg tatgtggtgc taacttatta
    57901 tccaaatagt ttgacagtct atttataagt ctagtggtat ttctatttgt gctcaaaagt
    57961 attcttttat attttttagc cttttcaatt acatctggct tgatttccaa gtctctagaa
    58021 attattaacg ctggtatttc atatgagaaa aatctatcta gtacttcttc ccgaatatga
    58081 ctatccatta atccaaaaaa attatattct gtctttccaa ctatttgtat tctttcatat
    58141 gcaaaataat caaaatatcc tgcaaactgt aatcctggtc tatttatatc ttgagagtag
    58201 acataataat ctacatcatc aggcatgtat actactttta acttcaactc ttttattatc
    58261 tctcttattg atactttatt gctagtttcc attaattttc ttcctttcta aaaaaattat
    58321 aaacattatc tgcaatgctt ttattcattc catctacttc taaaagttct tccatagtag
    58381 ctttttttat agcatctaca tctttaaagt gatttaataa tgatttcttt cttttttcac
    58441 ctattccttg tatatcatct aagatagatt ttgtcaaagc tttatttctt agacttctat
    58501 gatatgttat tgcataatta tgaacttctt cttgtatact agcaataaat ctatataaat
    58561 tagttgtttt atctagttct atttcttttt ctttgcatat caatccttta gttctatgct
    58621 tatcatcttt gtacattccc caaagaggta tatctacatc attgagttct agtacttttt
    58681 ttactgcact aacttgtcct tttccaccat ccaacaatat caagtcaggt aaatttccat
    58741 gttttaatct tctatctaca atttcagcca tagaatcata atcattaggt ccaataactg
    58801 tctttatttt atatctccta tattccttct tatctttttt agcattcgta tacactacca
    58861 tagaaccaat cgaatctaca ccttgtatat ttgatatatc ataagcctct attcttattg
    58921 gcaacttttc tagatttaat atttgcttta attcttccaa tgctccaata cttttttcat
    58981 attttctttt attcatatca gaaaattttt caagatattc tacagcattt ttcctaacca
    59041 tttcaactaa gcttttcttc tctccctttt gaggaactct tattgttact ttttgcccct
    59101 ttttagatga cagccattct tctaatatag aactatcttc tatctcatct tctataatta
    59161 attctttagg tatatactct tgttcattat aaaattgttt tacaaatgaa cttaatatag
    59221 aagctcttgg actatccatt accccttcta atataaaatg ttccctacct acaatcttac
    59281 catttcttat aaaaaatacc tggacacaag cttcattatg agctcttgcc attgcaacca
    59341 catcttggtt taagtcactt acagtagcat ctattttttg tttctgtatc atctcttcaa
    59401 ggctctttat cttatcccta tatacagcag cctcttcaaa tctaaagttc atagaactct
    59461 cattcatttt ttcctttaaa agttccatca atttttcttc tttaccagat aaacacatta
    59521 taatctcttc tatcattttt ccatactctt ctttagaaac atttcctgta caaggtccta
    59581 aacatttatt tatgtgtaga tttaaacaag gtcttgtctt attctttatt gctttatcta
    59641 tatctatttt acagcttctt attggatacg tactacttat aagctccaag gtatcattca
    59701 cagcagttat attggtatag ggcccaaaat actttgcctt atctttaaga actcttctaa
    59761 cttttaagat tcttggataa tcttcattcg tagttacttt tatatatgga taagttttat
    59821 catctctaag cactacatta tactttggtc tgtatctttt tattaaatta cattcaagta
    59881 ttaatgcctc taactctgaa tccgttataa tatactcaaa cttatatata ttcttaacca
    59941 tagattttac tttagatgta tggttttttg aagattgaaa atactgcctt accctatttt
    60001 ttagagatat ggcttttccc acatatatta tatggtcgta tttgtctttc attaaatata
    60061 ctccgggctc agaaggtaat ttttttaaat gctcttgtat atcaaacatc tcgccctcca
    60121 aaacattaaa ttttatacta aaattatacc ctaaaatatg aattttaaaa agttatacaa
    60181 tttccagtgc tttaaacaag ttaaagccca tattcccttc tataattgat ttgaaaacaa
    60241 tgttaaccat gaagagtaat atggacttta ctttgtatta ctatttacaa cttatatttg
    60301 actaatttac ttataacaaa acagtttatc gtatatctgc tctaaaattt ttcacaattt
    60361 atataactta agaaaaatat ttctttaaga attgacctgt ataagaacca tcaactttag
    60421 atacttcttt tggtgttcca gttgcaacta tagttccacc cttatctccg ccttctggtc
    60481 ctaagtctat tacataatca caagtcttta taacatctaa attatgttct atgactataa
    60541 ttgtatttcc tgtatctgct agtctttgta atacttggat tagcttgtct acatctgcca
    60601 tatgaagtcc agtagtaggt tcatctaata tatacaaagt ctttcctgtt ggtcttttac
    60661 taagttcagc agctaatttt atacgttgtg cttctcctcc tgataattga gttgaaggct
    60721 gtcctaattt aatatatgaa agtcctacat ccattaaagt ttctaatttt ctttttatat
    60781 ttggtatatt ttcgaaaaac tcaacagctt cttccacatt catatctaat atatcagata
    60841 tagttttatc tttgtatttt acttgcaatg tttctctatt gtatctttca cctttacaaa
    60901 tttcacaagg aacatataca tctggtaaga aatgcatttc tatttttatt attccatcac
    60961 ccttacaagc ttcacatcta ccacctttta cattaaaact aaatctacct tttttataac
    61021 ctcttgcttt agcttcatta gtagatgcaa aaatatctct tataaaatca aatacacctg
    61081 tataagtagc aggatttgaa cgaggtgttc ttccaatagg actttggtct atatttataa
    61141 ctttatctat actttcaatt ccttttatct ccttatgctt accagctctt tgcttaagtc
    61201 tattcacttt acttgcaaca cctttgtaaa gtatatcgtt tattaatgta ctttttccag
    61261 aacctgaaac acctgttatg catgtaaact tacctaatgg gaactttaca tcaatatttt
    61321 tcagattatt ttctgatgct ttaactattt ctataaaact tccatttcct tctctagtag
    61381 tctcaggaag caatatttgt tttttaccac ttaaatattg acccgttatt gagttctcat
    61441 tttcaattat ttcatctaaa gtaccctgtg caactatttc accaccatgt atacctgcac
    61501 ctggaccaat gtctataaca taatcagctt ctctcattgt gtcttcatca tgctctacaa
    61561 cgattaaggt atttcctaaa tctgttagat gtctaagagt agttataagc ctatcattat
    61621 ctctttggtg aagccctata cttggctcat caagtacata taaaactcca accaatgcag
    61681 aacctatttg agtagctaat cttatacgtt gcgcttctcc tcctgataaa gttccagctt
    61741 ttcttgataa atttaaataa tcaagaccta catctcttaa gaacatagct cttcctttta
    61801 tctcttttat aatctcatga gctataaatc tctgtttttc tgtaagattt atattttcca
    61861 taaagtcaat caattcattt acagataagt ttgtaacttc cattatattt tttccatcaa
    61921 ctaaaacaga taaaacttcc tttttaagtc tcatcccttt acactttgga catggtctct
    61981 ctgccatgta ttcttcaatc ttatctctca tgtaatctga attagtttct ctatatcttc
    62041 tctctaagtt tactattaca ccttcaaagt atgatttata atttctagtt cctccaaatt
    62101 ttgactcata agtaaactct acaattatat tatctttacc ataaagtaat tcctccacaa
    62161 aatcatctgg taaatcttta aacggtgttg tcaaagatac attaaaatgc tctgctaaac
    62221 tttttatcat tttactgtaa taagtgtcat cattaacacc tgttgaaccc catgctgcca
    62281 ctgcaccttg ttttattgat aaatctttgt ttggtactac taattctggg tcaacttctt
    62341 tactttcccc aagaccatta caaacatcac aagcaccaaa gggagcatta aatgaaaaca
    62401 ttcttggaga taattcttct atgccaattc catgttctgg gcatgcaaat ttagttgaaa
    62461 aaagaatttc ttctccatct attatttggg ctattacaag accatcagat agcttaactg
    62521 cagtttcaat tgaatctgct agtcttgatt ctattccatc tttaattact attctgtcca
    62581 ctacaacttc tatattatgt ttttgatttt tatttaagat tatatcatca ctaacttcat
    62641 agttttcacc attaactcta actcttacaa atccttcttt tttgatatta tcaaagactt
    62701 ttttatgtgt acctttttgt cctctaacaa ttggtgaaag aatttgtaat ttcgttctat
    62761 ctggaaaatc tagcatttta tcaactattt cttgaatagt catctgactt attttttcac
    62821 cacatgtagg gcaatacaca tctcctactc ttgcaaataa tagtctcaaa taatcatata
    62881 tttctgttac tgttccaacc gtagaacgtg ggttttttga ggtagtcttc tggtcaattg
    62941 agatagctgg tgataaaccc tctatatatt ctacatttgg cttttccatc tgacctaaaa
    63001 attgtcttgc ataagcagat agactttcta catatcttct ctgtccttct gcatatattg
    63061 tatcaaatgc caaagaagac ttcccagacc ctgacaaacc tgtaaaaaca ataaatttat
    63121 ctcttggtaa ttctaaatct atatttttta aattatgttc ttttgctcct cttattataa
    63181 ttttatcttc cataatgttg tttttacctt tctatttttc caatttttct tctaattgtt
    63241 tcactttatc tctaagttct gctgctcttt caaattgtaa gttttgagca gcttccatca
    63301 tctctgattt taatttatct atattagctc ttatttcgtc tttatcatct gtatcagata
    63361 ttccatatac aacttcttcc tctgcaacct tagtagcttc tatactatct cttatatttt
    63421 tctgtatagt tttaggaatg atattgtgct cttcattata taaattttgt atatctcttc
    63481 ttctctttgt ttcatcaata gcattttgca ttgagtcagt tatcctgtct gcatacataa
    63541 ttactcttcc attttcattt ctagctgcac gtccaatagt ctgtattaaa gctgtttcgg
    63601 aacgtaagaa accttctttg tctgcatcta aaattgctat aagtgaaact tctggtatat
    63661 ccaatccttc tctaagtaag tttattccta caaggacatc aaacttccct aatcttaaat
    63721 ctcttattat ttctgttctt tctaatgtaa ctatatctga gtgtaaatat ttaactttta
    63781 tccctatttc tttaagatag ttagtcaagt cctcactcat ttttttagtt aaagtggtta
    63841 taagcactct ttcatttttt tctatagttt tagttatttc tcctaccaaa tcatctattt
    63901 gattatttat aggtcttact tctacaattg ggtctaaaag gccagttggt cttattatct
    63961 gttctgctat tgtctctgag tgttgaattt cataaggccc tggtgtagca cttacaaaca
    64021 acatttgatt tatatttcct tcaaattctt gaaaatttaa tggtctattg tcaagtgcag
    64081 aaggtaatct aaaaccattc tctataagtg atgtttttct agacctgtct cctgcataca
    64141 tacctcttac ttgtggtata gtgacatgtg cctcatctac aattatcaaa taatcatctg
    64201 ggaagaaatc cattaaagta tatggtcttt ctccttctga ccttcctgta atatgtctag
    64261 aatagttctc tatcccctga caaaatccta tttcctttaa catttctata tcatacttag
    64321 ttctttgttc aattctttgt gcttctaata gcctatcatt ttccttgaaa aatttaattt
    64381 gttcttgaag ctcgttttct atttctacaa ttgccttttc aattctttct ggcgttgtta
    64441 catagtgaga tgctgggaat ataacaacat gatttctagt accaacaatc ttccctgtta
    64501 cataatcaat ttctgttatt ctatctacct catcaccaaa aaattctatt cttattgctt
    64561 tttcatcatt actagctggg aatatttcta gtatatctcc tctaactcta aaggtacctc
    64621 gtgtaaagtt tatgtcattt ctttcgtatt gtatctctat taaccttttt attacatcat
    64681 ctctgtctct ttgcatacct ggtcttatag ataacataag ttctttatag tcttttgggt
    64741 caccaagtcc atatatacaa gatacagatg atattattat agtatctctt ctctctaaaa
    64801 tagatgctgt agcagaatgt cgaagtttat ctatttcatc atttatgctt gcatcttttt
    64861 ctatataagt gtcactgtga gctacatatg cttctggttg ataataatca tagtaactta
    64921 caaagtattc aactgcattg tctgggaaaa attctttaaa ctcactgtaa agttgtgctg
    64981 ctagagtttt attatgagcc attattaggg taggtttctt aacttgttga atgatatttg
    65041 ccattgtgaa tgtttttcct gaacccgtta cacctaataa tgtcgaaaat ttctcatttc
    65101 tatttataga atccactatt gatttaatag cttctggttg gtcacctgta ggtttgaagt
    65161 ctgattttat tttaaaatcc atagtatcac tccttttttc gaacattagt tcctgacatg
    65221 tattattata tcataccttt ataaaattgt ttaagttatt ttaaatattt tacccattta
    65281 aattttactt aaatctaaaa cataaaaaaa gacttctatc tttgcaatag aagtctataa
    65341 ttcatggaaa ataaatactt tattcaactt acataataaa atcaaatgct tctttttcaa
    65401 ctccatctaa ttttaaatta aacattttta atatagttgc tgcatgtgct ctcaggtctc
    65461 cttcttctat aaccacacca cctttaatat ttggtccaaa agctataaat ggaggtctat
    65521 tacctttagt aggtaaatga ccatgtgtcg caacagcaaa cttgtaatct tttatatctg
    65581 aatcttttat aatacttcct tcgaaatcat ttccaaatga aattccttca agaccttcaa
    65641 ttaccatttc aaaatcacct tcaagaccaa ggttagatgc ttcctctttg gtaaaaatat
    65701 tctctatgaa taattcttct ttaaattctt caagcagttc tcttaactct gttaacctat
    65761 ctaagttatt tactattatt tgagctgata ttccagaaga atttacatag gcatcaaaat
    65821 ccttaacttc tccattttca acttttataa atccatttga tttaagcaag acatttggat
    65881 ttataacttt atcaactcta agatgaccat ggtccccaag tattataaaa tttgtatctt
    65941 tgtatgtacc tgcatccttt gtagcctgaa taatatctcc tagccattta tcattcattt
    66001 ttaatgcttt atctacttcg tcattaaata agccataatt gtgtcgtgta tggtccaatg
    66061 tagctaaatg tattagcatt aaatctggtt tatattcctt tattatatct actgaacagt
    66121 ttactccaaa taaatccatg ttgggttcta atttccaatc gatataatga caatgtctat
    66181 tgtaaatacc gtccattata accttactgg aacttcgttc aaaagtttct cttgggtcat
    66241 cttctctact aggagcccat atttctgcaa tattataatc tatatttgga tttgctccca
    66301 ttacaggcca taatacacta gaggtagtta gattattttc ttttgctaca tctataatag
    66361 tttttgcttt tatgtccttt gagtaccagt accagtcttt attttcttta tttgggtcaa
    66421 atttttcatt atgatatata ccatgttttt taggatatac tcctgtaacc atactagtat
    66481 gacacggata tgtcagagtg ggataaacac aatttatatt ttttactatg gagcaatttt
    66541 ctagtataga tttaaagttt ggtagatttt ttacaaattc caagtctttt tcaaataaag
    66601 aatctactga taatactata acctttgtca tttacattac ctcttcattt atatattatt
    66661 gaatactttt aatcaactta caagtctata taattattta tttgttttat ctattactgc
    66721 ttgcattgca gaagttcctt tgcttactac atcttttgga tttgcattta aatcagtaag
    66781 ccccttttta atctcatcca ttagcttatc agttgcttcc ttgtatccat ttaacattgg
    66841 aagtgcaaca gcatattgta attggtcagt tgcaacctta tattgaggtt tttctttata
    66901 taatgtttgt aacttttctg agtttgttgc atcttcagtt gttggtaagt atcctgttga
    66961 tgaactaaac tgaacgattt tatctgtttg tgtcatccat tctataaatt ctgcacttgc
    67021 ttctttttct ttatctgttc caccttcaag cataactaga ttagctccac ctgtaggagt
    67081 tgcgtatttt tgattttttg gtaagaatgc tgttgatatt tcaaacttac cttctgtttg
    67141 ttgcataagt cctgctaaat ctgctgttga tgtaaatatc atacctactt taccatttac
    67201 aaaatcttgt tttgctacgt cccaggcatt ataatcttct ccaggaggca ttttcattat
    67261 tccagctttc atcatatctt gccagaactt aactggtgct tgtcctgcct cattattaaa
    67321 tgctactttt ttaccattag ttatttctcc tccactttgc attaccatag cttcatagaa
    67381 ccaaatatct attggtgttt caaaaccata agtatcttct gatttatttg tcattttact
    67441 agcataatcc ttaagctctt cccatgattt tggacctgaa gggtcaagac ctgctttagt
    67501 tgccatatct ttatttatgt ataatattgg tgtacttcta ttaaatggca taccaacaaa
    67561 cttatcctca taatatgaat ttgttaaaag accagaaaag aatctttctt gatatgtttt
    67621 atcaaaatat ttactcatat ctactaaagc acctgctgat gcgaatgtac ctgtttgagt
    67681 tatttctaat aatgttacat ctggttggtc tttagatgtt aaggctgcct gtagttttgt
    67741 tgcattttca tagtaatctt tctgttttaa catatttact tgtacatcct tatgttcact
    67801 attaaattgg tcaaccattt tttgagcagt ttctccatta gttccaccta aaggagccca
    67861 gaaatctatc ttcgtaatat tgctatcagt cttttctcct ttagatgcat ttgcatcatt
    67921 agaatttgaa cacccaacta aagaacataa taataatgtt attgctaatc ctgttgctaa
    67981 ttttctttta agcttcattt tcatcctcca aatttagtct ttaatttttt attttattcc
    68041 tgaatacata aaagcttctt ttactttttt attcgcaaat atataaacaa gaattattgg
    68101 taaaattaga attatatttc ctgccattat tacattccat gcagtaattc cttctgaaga
    68161 tttaaggagc gcaactccta ttggtaaagt tcttattgca tctgtatttg tcattactaa
    68221 gggccagaaa taattattcc aatggtatat aaaattaaat aatataaatg ttattactgc
    68281 tggttttgcc ataggaacca ttattctaaa cattattttt aagtcagaag cattatctag
    68341 tttagctgct tcaataattt catctgaaat ctgcataaaa ttctgtctaa gcagaaatat
    68401 cccaaatgaa gatgtcataa atggaattat aagtggaaca taagtattta taaatccaaa
    68461 cttactcatc atcatataga ctggtagaaa agttacttgt ggtggaatca taagtcctac
    68521 aagcaaaagc ccaaatagca ttttttcacc tttaaattta atcttagaaa atgcatatgc
    68581 tgctggaacc ataactaaaa attgtacaat taaaacactt cctgttacaa atacactgtt
    68641 tagcaaatat ctaaaaaatg gacctgaatg ccatgctgta ctataatttt ctaacactat
    68701 atcatttggt ataatagtgg gcggtaattg catcatttct tgtggatttt taaaggatgt
    68761 agatagcatc catataaaag ggaatataaa tattgcagat aaaagtaata gaattaatat
    68821 ttctattgat tttgatgcta ttttttttat atcaactttg tcttttttga taggttgtat
    68881 aatatccatt gtctcctcct tttggataaa ccttataata tctacttttt ctttattgat
    68941 aatgaacttt ctttgataag agtctaaagt tagcatatgt agcaatcata actatagcta
    69001 acaaaaacat actcgctgca ctcgcttgcc ctatgtcata gtatataaat ccagactcat
    69061 atatataata agataacatg ttagttgaac ccactggccc accttgtgtc attatactta
    69121 tctcatcaaa tacttgaaaa gatgcagttg ttgttgttat cataagaaaa aatattgttg
    69181 gtgataatag tggcaatgtc actttaaaga aattcgttat tttgtttgca ttatctaatt
    69241 tagatgcttc atatatatag tttggtatgg atttaagacc tgataacact attaagatat
    69301 tatatccaag agtcttccat attcctatta gaattagtga cattaaagct gaactttcac
    69361 ttgaaagcca ctttgatgtt ggtaaatgta atgtcgatag tatccagttt aaaaagccat
    69421 attgtggctc cataatccaa agccacaata cagctacaga tactagtgaa attacatgtg
    69481 gtgtaaagat tatactttgc gttaaattgt gtattataga atttttattt agccaaacag
    69541 caagtactat ggctagtgat atagatatag tcaccataaa aaaagtataa attgcagtgt
    69601 ttgttatagt ttgtataaac tctggattct ttaaaagttc tgtataattg tttaagccta
    69661 cattttcaaa ggttgaacta agaagactac cagatttgaa gcttagagat atcgtcttaa
    69721 ttattggata gactataaac aataaagttc ctataatagc aggtgttata tataaatatg
    69781 ctttattaaa ttgctttttc ataaatatct cctttgattt tagaatacat acttttacat
    69841 acttttacat cttctattct ttctccattt ttatcaaaat aatataaatc tttttctaat
    69901 acacttattc ttaaagttct tccaatatca aatatatcat tttccgtttt gactcttatc
    69961 tctctattaa gaacagataa acaatatata gtttcatttc ccaacacttc tttagttaca
    70021 acttttccaa atagactaaa tacatcatca tttttcccat ctatgtttat actctctagt
    70081 gttgcttttt ctggtctgaa tccaaattta atatcatttt ttatatctag tatgttcata
    70141 caaggactcc ctataaattg agctacaaat aaatttttag gattttgata tatcttcttt
    70201 ggagaaccta tttgcattat ctttcctttg ttcattataa ctatcttatc tgccattgac
    70261 attgcctcaa cctggtcatg agttacataa acaaatgtag actttagttt ttgatgtaat
    70321 tgtattaatt ctgttctcat ttgatttctt aatttagcat ctaaatttga caatggttca
    70381 tccattaaaa atacctttgg atttttaacc atagctctag caagtgccac tctttgtctt
    70441 tgacctccag ataagttgcc tggtttcaca tttaaatatt ctctcaatcc tactacatca
    70501 ataacttctg ttataagttt ttctcttttt tctttttcta cttttttgtt tttaagacca
    70561 aattctatgt tttctctaac agtcatatgt ggatataatg cataattttg aaataccata
    70621 gctatatccc ttttactagc atccgttttt gtaacatcat tttcttcaat cttcaaccta
    70681 cctgaagtta tatcttcaag acctgcaatc attcttaacg tagtagattt accacatcca
    70741 cttgggccta ccaatactgt aaaagaacca tcttctatag taagatttaa attttctata
    70801 actgtatttt ttttattata agattttgtt acattttcta gtcttatatc tgccattttt
    70861 atcctcccaa aatatttaat ttaattctac gatttactta tagattaata atactcttaa
    70921 tttgtaaagg atatattaag acaaagtgaa tatatggtaa acttattaaa ataaaggtta
    70981 aattataaac attttttgtt aaatatactg aagttaagat gatatacagc ttatgttagc
    71041 tataattttc tatatttttc atattcatgg tttgctatca caatgtaatt ttaatttatg
    71101 aagagtcata taaaactatt tattttttat ataatttggt ttgaaagtaa aaaagacctc
    71161 tatgggggat agaggtcttt aagtggggga gattgagtaa tttatttttg ctatattaag
    71221 ttttacaatt atattatgtc ccaaatttac aaggtttaaa cataaaaaat aaaaattttt
    71281 taatttttat aaatttaccc
//
LOCUS       DAYAKB010000015        69139 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.015, whole genome shotgun sequence.
ACCESSION   DAYAKB010000015 DAYAKB010000000
VERSION     DAYAKB010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.015"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..196)
                     /locus_tag="ACGI3L_001143"
     CDS             complement(<1..196)
                     /locus_tag="ACGI3L_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196869.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLIS"
     gene            complement(210..1541)
                     /locus_tag="ACGI3L_001144"
     CDS             complement(210..1541)
                     /locus_tag="ACGI3L_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFG9196870.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(1555..3120)
                     /locus_tag="ACGI3L_001145"
     CDS             complement(1555..3120)
                     /locus_tag="ACGI3L_001145"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucoside-specific PTS transporter subunit
                     IIBC"
                     /protein_id="HFG9196871.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(3290..4075)
                     /locus_tag="ACGI3L_001146"
     CDS             complement(3290..4075)
                     /locus_tag="ACGI3L_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9196872.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(4242..5441)
                     /locus_tag="ACGI3L_001147"
     CDS             complement(4242..5441)
                     /locus_tag="ACGI3L_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HFG9196873.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(5963..7300)
                     /gene="xylA"
                     /locus_tag="ACGI3L_001148"
     CDS             complement(5963..7300)
                     /gene="xylA"
                     /locus_tag="ACGI3L_001148"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009045 - xylose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HFG9196874.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(7396..8946)
                     /gene="xylB"
                     /locus_tag="ACGI3L_001149"
     CDS             complement(7396..8946)
                     /gene="xylB"
                     /locus_tag="ACGI3L_001149"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFG9196875.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVSSLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSKVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            9154..10314
                     /locus_tag="ACGI3L_001150"
     CDS             9154..10314
                     /locus_tag="ACGI3L_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9196876.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(10470..10874)
                     /locus_tag="ACGI3L_001151"
     CDS             complement(10470..10874)
                     /locus_tag="ACGI3L_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9196877.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNANLLSDDE"
     gene            complement(10895..11377)
                     /locus_tag="ACGI3L_001152"
     CDS             complement(10895..11377)
                     /locus_tag="ACGI3L_001152"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196878.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(11397..12206)
                     /locus_tag="ACGI3L_001153"
     CDS             complement(11397..12206)
                     /locus_tag="ACGI3L_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9196879.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(12199..12978)
                     /locus_tag="ACGI3L_001154"
     CDS             complement(12199..12978)
                     /locus_tag="ACGI3L_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9196880.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(12978..15056)
                     /locus_tag="ACGI3L_001155"
     CDS             complement(12978..15056)
                     /locus_tag="ACGI3L_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HFG9196881.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(15855..16376)
                     /locus_tag="ACGI3L_001156"
     CDS             complement(15855..16376)
                     /locus_tag="ACGI3L_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3072 family TudS-related putative desulfidase"
                     /protein_id="HFG9196882.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKIKDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            16542..17108
                     /locus_tag="ACGI3L_001157"
     CDS             16542..17108
                     /locus_tag="ACGI3L_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3073 family putative ECF transporter S
                     component"
                     /protein_id="HFG9196883.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(17325..19388)
                     /locus_tag="ACGI3L_001158"
     CDS             complement(17325..19388)
                     /locus_tag="ACGI3L_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HFG9196884.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYSNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(19769..23104)
                     /locus_tag="ACGI3L_001159"
     CDS             complement(19769..23104)
                     /locus_tag="ACGI3L_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFG9196885.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMMDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTENFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(23154..23582)
                     /locus_tag="ACGI3L_001160"
     CDS             complement(23154..23582)
                     /locus_tag="ACGI3L_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196886.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(23572..23952)
                     /locus_tag="ACGI3L_001161"
     CDS             complement(23572..23952)
                     /locus_tag="ACGI3L_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFG9196887.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(23985..25157)
                     /locus_tag="ACGI3L_001162"
     CDS             complement(23985..25157)
                     /locus_tag="ACGI3L_001162"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFG9196888.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIS
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITSEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVEVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGEPINNTKKFDMKKIKEISIYLKRGVSPKYVEQSN
                     IKVINQKCIYWRNLKVENCKYYDENLKEKIEDIFLKQNDILINSTGTGTLGRCVKFNK
                     IDNSEYIADSHVTVLRSISNNLNSDYFAALFEFTNIQDTIYRKCVNGSTNQIELSVSK
                     LGEYLIMVPPIEFQNQFSEFVKQVDKLKLKIETNLKELEDNFNSLMQKAFKGELFN"
     gene            complement(25161..26624)
                     /locus_tag="ACGI3L_001163"
     CDS             complement(25161..26624)
                     /locus_tag="ACGI3L_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFG9196889.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIAVGLEELERMLEV"
     gene            complement(27134..28003)
                     /gene="gatY"
                     /locus_tag="ACGI3L_001164"
     CDS             complement(27134..28003)
                     /gene="gatY"
                     /locus_tag="ACGI3L_001164"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HFG9196890.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(28023..29939)
                     /locus_tag="ACGI3L_001165"
     CDS             complement(28023..29939)
                     /locus_tag="ACGI3L_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFG9196891.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVAKLNNEEIKSV"
     gene            complement(29942..30862)
                     /locus_tag="ACGI3L_001166"
     CDS             complement(29942..30862)
                     /locus_tag="ACGI3L_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HFG9196892.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(30964..31716)
                     /locus_tag="ACGI3L_001167"
     CDS             complement(30964..31716)
                     /locus_tag="ACGI3L_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9196893.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(32108..33553)
                     /locus_tag="ACGI3L_001168"
     CDS             complement(32108..33553)
                     /locus_tag="ACGI3L_001168"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9196894.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            complement(33575..33928)
                     /locus_tag="ACGI3L_001169"
     CDS             complement(33575..33928)
                     /locus_tag="ACGI3L_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9196895.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(33957..35189)
                     /locus_tag="ACGI3L_001170"
     CDS             complement(33957..35189)
                     /locus_tag="ACGI3L_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9196896.1"
                     /translation="MNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMVFVGSL
                     VTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMETMKNKKFESMSVVAGLAGA
                     GLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGEDSALP
                     DFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFVLLNFL
                     VVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWITLGGL
                     GATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPMWIGTV
                     VISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLLFMIWY
                     PFFKAYEKEEIKLESQEV"
     gene            complement(35212..35529)
                     /locus_tag="ACGI3L_001171"
     CDS             complement(35212..35529)
                     /locus_tag="ACGI3L_001171"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9196897.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            35771..37684
                     /locus_tag="ACGI3L_001172"
     CDS             35771..37684
                     /locus_tag="ACGI3L_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9196898.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGAFILSSKKGYKVNLNTNCQTKIDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLVGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(37807..38961)
                     /locus_tag="ACGI3L_001173"
     CDS             complement(37807..38961)
                     /locus_tag="ACGI3L_001173"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFG9196899.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEKLDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLDSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(39240..41855)
                     /gene="mngB"
                     /locus_tag="ACGI3L_001174"
     CDS             complement(39240..41855)
                     /gene="mngB"
                     /locus_tag="ACGI3L_001174"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HFG9196900.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPDRKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLIAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEDWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(41999..43924)
                     /gene="mngA"
                     /locus_tag="ACGI3L_001175"
     CDS             complement(41999..43924)
                     /gene="mngA"
                     /locus_tag="ACGI3L_001175"
                     /EC_number="2.7.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HFG9196901.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(44054..44779)
                     /locus_tag="ACGI3L_001176"
     CDS             complement(44054..44779)
                     /locus_tag="ACGI3L_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9196902.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(45042..45812)
                     /locus_tag="ACGI3L_001177"
     CDS             complement(45042..45812)
                     /locus_tag="ACGI3L_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HFG9196903.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(45814..47262)
                     /locus_tag="ACGI3L_001178"
     CDS             complement(45814..47262)
                     /locus_tag="ACGI3L_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9196904.1"
                     /translation="MKRFLNKMMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVP
                     AISNISNIVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNA
                     GVFGGIIVGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIY
                     PQAAMNQFGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVI
                     RGEIPRFMAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALT
                     SFMATVTEPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSF
                     SYGDKAWLVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLS
                     HGNFSYMAKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLS
                     NTSVQIIIGTDVVKVKDEMEMQLDELRKQADA"
     gene            47632..48354
                     /locus_tag="ACGI3L_001179"
     CDS             47632..48354
                     /locus_tag="ACGI3L_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9196905.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            48551..50218
                     /locus_tag="ACGI3L_001180"
     CDS             48551..50218
                     /locus_tag="ACGI3L_001180"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFG9196906.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(50314..51633)
                     /locus_tag="ACGI3L_001181"
     CDS             complement(50314..51633)
                     /locus_tag="ACGI3L_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9196907.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(51674..52420)
                     /locus_tag="ACGI3L_001182"
     CDS             complement(51674..52420)
                     /locus_tag="ACGI3L_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFG9196908.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(52664..54673)
                     /locus_tag="ACGI3L_001183"
     CDS             complement(52664..54673)
                     /locus_tag="ACGI3L_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9196909.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(55111..56544)
                     /locus_tag="ACGI3L_001184"
     CDS             complement(55111..56544)
                     /locus_tag="ACGI3L_001184"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9196910.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(56631..58547)
                     /locus_tag="ACGI3L_001185"
     CDS             complement(56631..58547)
                     /locus_tag="ACGI3L_001185"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9196911.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQILITFDIESISKEGYCLETPVVVTNYSDYVDILENTQ
                     KHVNNSQELITVLA"
     gene            complement(58621..59481)
                     /gene="licT"
                     /locus_tag="ACGI3L_001186"
     CDS             complement(58621..59481)
                     /gene="licT"
                     /locus_tag="ACGI3L_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFG9196912.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(59832..61019)
                     /locus_tag="ACGI3L_001187"
     CDS             complement(59832..61019)
                     /locus_tag="ACGI3L_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9196913.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(61033..62424)
                     /locus_tag="ACGI3L_001188"
     CDS             complement(61033..62424)
                     /locus_tag="ACGI3L_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFG9196914.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     regulatory      complement(62568..62747)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(63019..64671)
                     /locus_tag="ACGI3L_001189"
     CDS             complement(63019..64671)
                     /locus_tag="ACGI3L_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9196915.1"
                     /translation="MKDKLQVLSGAMMIPVILLVVAGVFIGLGSAFANMENVSALGLS
                     GLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKKEKGWGALGGIVLFIGM
                     HTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGSFLGIFSYDCSIFGAII
                     AGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLGTAMYFIWPPVGLALSK
                     LGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVGGTMEVGGAIYEGVNNI
                     RLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLADNANKKKAISILIPAIV
                     TAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFNVSIMGESFRNMFPNLL
                     QPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSEEVKLYSKKEYRERQSV
                     DAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNCATRLRVELNSIDGFYE
                     DGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD"
     gene            complement(64691..66094)
                     /locus_tag="ACGI3L_001190"
     CDS             complement(64691..66094)
                     /locus_tag="ACGI3L_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9196916.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(66358..66849)
                     /locus_tag="ACGI3L_001191"
     CDS             complement(66358..66849)
                     /locus_tag="ACGI3L_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9196917.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(66875..67687)
                     /locus_tag="ACGI3L_001192"
     CDS             complement(66875..67687)
                     /locus_tag="ACGI3L_001192"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9196918.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(67700..68653)
                     /locus_tag="ACGI3L_001193"
                     /pseudo
     CDS             complement(67700..68653)
                     /locus_tag="ACGI3L_001193"
                     /inference="COORDINATES: protein motif:HMM:NF012678.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(68777..>69139)
                     /locus_tag="ACGI3L_001194"
     CDS             complement(68777..>69139)
                     /locus_tag="ACGI3L_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFG9196919.1"
                     /translation="QKLSTKLIKENDIICIEDLQVKNMIKNRKLSRSISDVSWSEFIR
                     QLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDIN
                     ASINILKEGLRLITIQNK"
BASE COUNT        22231 a        12620 c         7384 g        26904 t
ORIGIN      
        1 tagagattaa atttaaactt gcattaacat cattgtttaa aagttgtgaa aatgaaatat
       61 ttgtaaataa tgatgtcaat tctaaataca ctatatataa aacaggtaat attagaaaac
      121 aaaccataac cactgaaaga aatatatttt catcttttaa tactgctgtg atatttttta
      181 ttttatttgt tatcatgttt ttgttctcct tatttaaaag ttggccagaa atccttatta
      241 gccacaatca tttcatctaa gatttctttt gctacttttg cacttggaac agttttactc
      301 atagtaaacg actgccataa tttttgataa cttttttcta tccatgcttc tacagctaat
      361 ttttcagaag caacttgttg ttccattaaa cctttttgga aagttggaat tttacctata
      421 gacataggtt caaccatatc ttttccaaca aggcaaggaa tttcaaccat tgcatcatct
      481 gcaaaatttt caatagctcc attattagga acaatcagta aaaatctttc ctgagtatta
      541 aatgctaatg cacaagctaa ttcaacaata aattgagaat gttcacttgc atcaaaccat
      601 gtatctcttg ctgtgccatt ttttataatt ctttcacatt cttcgaatgt atccttttct
      661 cttctatcca taatttcatt tgctcttgta taatttggat tagcatgttc aacagtttca
      721 tcagccatta aataatattt taaataagta ttaggtaatg tagtcggttc tatttccaat
      781 aaatcctttg ctgctctcat agtttctaac caactagatt ctttgtgttg accttgaggt
      841 gtaaattcct catatccttt tttagcacaa tattcctgta atttaggcat taaatcattt
      901 ccttctttgt ccttaatact tgtccaccac ccgaaatgat tcaatccata atatctaaca
      961 tcaaagtctt tacgagaatt taaacctaaa actctagcaa atatttcctc taaacatact
     1021 ggcatatcac aaatattaat aattcttgaa tttggtctta atacacgaca tgcttctgca
     1081 actatagctg ctggatttga ataattaagc atccaagcat ttggagaata tttttccata
     1141 taatcaatca tttcgattat tggacctatt gttcttaatc cataggcaat tccacctgcc
     1201 ccacaagttt cttgaccaac aaccccatat tttagtggaa ttttttcatc ttgttcacgt
     1261 aaagcatata aaccaacacg aatttgtgcc attacaaaat caatatcagt aaatgcttct
     1321 tctggatttg ttgtataact aaatttaatt tctggatttt tctctctaac aattattgca
     1381 catgcttcag caacttttct ttgtctctca tcattattat catataattt aattgattca
     1441 ataggaaatt tagcaacact ttcaattaac attgttacaa ttccagcagt ataagtacta
     1501 cccccaccag caattagtat cctctgtctt tttctttcca tctttccttc tcctttataa
     1561 taaattttca aattcttctc ttacacttgg tactgaaagc ccaataataa tctgaatagc
     1621 ttttccatta tgcactaaac catgtgcacc tactgcctta aaatcttctt ctttagaaat
     1681 aattgagtca tctttcaagg ttaatctcaa cctcgtagca cagtttgtaa catctacaac
     1741 attttctgct ccaccaacta attttatgta ttcagatgct tgttgagagg ctttactcaa
     1801 tttatttcct ttttcatctt tagtttctaa gtattcattt ttagtatata gttttgtttc
     1861 ttcactatct tcctctctac caggagtttt catatcaaac ttcttaatta agaaagtaaa
     1921 tacaaagaac cagataaatg aaaatataat ccctacaaca acttgaacaa catatacctt
     1981 ccagtgatac attccaagag gaagccaatt taatacaacc cagttaataa ttcctccacc
     2041 aaaatcacca acaactccta gggcaaacga aatcgtttgc aagcatgcat ctaaaaatgc
     2101 atgtactagg aataaaagtg gtgctacaaa taaaaatgta aattctaacg gctcagtaat
     2161 tccagttaat actgcagtaa gagtagcagg aatcattaaa cctaatactt ttttcttttt
     2221 ttctggcttt gcagttacat agaaagcacc aaatacacct aatgaaccaa acaccttcga
     2281 taatccggat aatgaaaatc cgattggata catttccttt agagtcttag ctgaagtttg
     2341 aaaatcctga atatgagtag cccaatatac tgatgtacca cctggaacaa caacactatc
     2401 ataacaaatt ggtgcatata caaaatgatg taatccagtt ggtattaaaa tcttttgtaa
     2461 gaatgcataa caccaaactc ctatatttcc actatttata aaaaacgttt gcaaatgtct
     2521 aataacattt tgaatatgag gccaaataaa acaagttaat aatgcaactg gtatcataac
     2581 aaagaaacaa attgcaacta caagtgatga gcctctaaat aatccaataa aatctggcag
     2641 ttctttatca taaaatctat tatgaatata aatgacaata cctgatatta acaaagcacc
     2701 aaccatacca gtatctaatg ttttaatacc agcaatgctt acaagtccac ttccagcact
     2761 tatttcagct gcgaaatcaa ctccaaagct ttttccccaa aaacttaaca tagaacctac
     2821 aaaataatta aaagtcaaat acgttgctaa agcctccata caagctcttg cttgttgctt
     2881 ttttgcaagt gctattggta aagaaatagc aaataataat ggcaattgat taaataccat
     2941 ccaagctcca ctagatatta caccccaaaa ttggtaccaa atattttctg gtgtagcaag
     3001 tgaacccata attgactgat tttgaaatac aattgagaat ccaaccatta tcccagcaaa
     3061 agcaaataat agtgttggtg taaacattgc ccctccaaaa cgctgtattt tcttcatcat
     3121 ataaattact cccctcctca tatttttagt ttatctttgg ccttagatat ctattatttt
     3181 aacaggttaa taaatatata caatctttag ggtacattcg gagcttattc acagtcaaat
     3241 aagtttttgc acatttttat gttcaaattc tcataaaaaa aaagaatgac tacaatttgc
     3301 aatcaatccc ttctgtaatc attctatgcc ttttataaat actatattta ataaataata
     3361 actcaatcaa tataaaatat aacattgtca atttataact agggtgcatt tgtaaaaatg
     3421 agatattagt cgctgaaata taaattgatt catcacttaa atcagtcaat gtattatttt
     3481 taaactctgt aattgaaatt attttagttc ctattaattt taatcttcta gcaatattaa
     3541 gtgtattctc attctcacca cttagggata taataatcat aacatcattt ttactgacaa
     3601 tattgtaaaa agaatcatca aatgttcttc cctcaaaatc atatattatt tcttgacatg
     3661 ataagaacat tctctttatc tgttttgcaa ccacattttg aatatcacct gaaccataag
     3721 cgtatattgt tcttgattca taaagaagtt tacacaatgc atcataatct ttattttttt
     3781 gatcttcaac atacttaatt attgaattac atgcaatatc aaatgactga ttttctatga
     3841 catgaacctt ttctgattcc cagcttaata atactttaaa ctcactgaaa ccttttaaat
     3901 ctaatttttt aacaaatctt gtaatagttg cacgagacac attacatttc atagcaagtt
     3961 catttattga catcttacta caatgttttt tatttgcagt tatatatttc catattaata
     4021 aatctgtatc attcaattta ttataattta aaaaaatcat ttcttctaat ctcataaact
     4081 attaccccct ttaattaaaa atcgtcataa atattatacc aatattcaac attaaattac
     4141 agcgtattct tatatttact atttagccca taaaattgac tataaaaaat actgctataa
     4201 ttgatgttta aaaaaatgta gttttaattt tattctttta tctaataatt aatattttca
     4261 agttctagtg cttttcttat acaattatca tctttaaaat cagcagtcct tttacaatct
     4321 tttactttaa attctggaat agttttaaat tcctcatcac atattccatt cttatttaaa
     4381 tacatacaac ttgccattct aactattaga ccactatttt ttaaattaaa caatacaggg
     4441 tctatacacc ctccatctcc gccagtagtt tcaccaacta aagtcgcaaa tttattttct
     4501 ttacaaaaca ttgcaaatga ctctgatgat gaatatattt ttctatcaac aagtaagtat
     4561 atattaccct taaattttga atcatctgta gattttatag tataggaagt atcttcaaaa
     4621 tcattaaaat cttttataat ttctttaggt gcattttcct ttacacttgc tggtaaattt
     4681 tctacaggat ttaattttat atttcttgca tttgtatatt tttttactat ttcattatta
     4741 tttctataaa ttctataacc atttattttg acatcatttt ttatgagttt agatacgatt
     4801 ccctgccaat acctatcact tccacctaaa ttacctctta tatcaataat taaagcttta
     4861 tgtttttcta aagtgttaat ataatctcca attattttta aatcattatt tatagagcca
     4921 ttctttgatg acattgatgg taaatacata tatccaatct gacccttaat aacatccttt
     4981 aaaattaatt ctttttttac aaaaatatca tctggcattt ttattttaag attcatagag
     5041 tcatatctat ccacaacttt tttatcatta agaaaatcat accaatcatt attagagtat
     5101 gatttcttaa aaagttcata tcttttctta ttatctatta cttctgtgtg tttattattt
     5161 aaatcagata atatagatga cagttcttct ataaattctt catcattttc agtgtttttt
     5221 attcgttttg tatattcatc cttatttgct aaccaatcaa tattattaag cctcttattt
     5281 acacctagat atggatatcc tgtctttaca acattataca cataattaaa gtcatccacc
     5341 ttttcctctt cagacaactg attcttttga gaataagtag aattacctaa taatattata
     5401 aatgctaaaa taattactaa aaataatact ttctttttca tgtaattctc atccactttc
     5461 agattttata ttttaataca ttgtatcatt attttattat cacctaaaca gttaaaagaa
     5521 attcttgaag atatattcca ctattattct ctttaaaaat ttttatttgt attttcaaaa
     5581 ttatttcatg aaagttataa aataacaatt atattcaaat atctatttta ctgctatatc
     5641 ctgaaagtaa attcttatca gtgatatact aaaaaagata tgctaaaaaa tttatccatt
     5701 ataatgactt aaatttagat actttactga tttttattta ttagttgaga aagatattga
     5761 taattaaaaa tattgataac tatagaaatg attatttttt atagaaattt taaggatata
     5821 aactaattat acttaagtct atatccttaa tttatcatga ttatgagaat ttttacaaat
     5881 acttatcttt gtccgtttta gaataaaaac aagaacatat cctgttattt tattcaaaca
     5941 tccaagttta attactacac aattacttat tagaaattgt atctacttca tatatatatc
     6001 tgttaagtat agcttctagc atttcttgtc ttccagactt attctttata actggcattt
     6061 gcagtgcata agattctaac tctttaaatc caaccttacc ttctactata tccttaccta
     6121 taccttcact aaaacttgca tatctttctt tagtaaagtt ttcaaatacc tcatcttcta
     6181 ataatttatg agctattaat aatccctttg caaatgtatc cattcctgca atataagcta
     6241 ggaataagtc ttctacctca aaagatgctc ttcttacttt agagtcaaaa ttaaaccctc
     6301 ctggtgctat tccaccttgc tttaacactt catacatagc aagtgttgca tcatatatat
     6361 ttgttggaaa ttggtctgta tcccaaccta ataataggtc tccttgattt gcatctatac
     6421 tacctaaaac attgtttatt cttgctatat ttaattcatg ttggaaagta tgtcctgcaa
     6481 gtgttgcatg gtttgcttct atattcattt tgaagtattt atccagatta tactttctta
     6541 aaaatcctaa aacagtagca gtatcaaaat cgtattgatg tttagtaggc tcttttggct
     6601 taggctctat taagaattgt ccagtgaatc ctatttcctt agcatagtct acagccattt
     6661 gtaagaatct tgcaaagtta tccatttcaa gttctgtatt agtgttaagt aaagtttcat
     6721 aaccttctct tccaccccag aatacaaaat tttctcctcc taagtactta gttatttcca
     6781 tagctttttt aacctgagct gctgcatatg catatacatc tgcattacat gttgtagatg
     6841 caccatgaac aaatcttgga tttccaaaca tattggcagt tccccataat aactttatac
     6901 ctgtcttttc catattaact tttatatact caactatttc atctaatatc ttatttgtct
     6961 cttctaaatc tcttccttct ggtgctatat ctctgtcatg aaaacagaaa tactcaattc
     7021 ccatcttaga cataaattca aatcctgcat caactttaat ctttgctatc tcaattgggt
     7081 ctgttatatt attccaaggt ctctctactg tgcctactcc aaatgggtca ttaccctctc
     7141 cacataaagt atgccaatag ctcattgcaa atcttaagtg ttctttcata gtcttattac
     7201 ctaccacttg ttcaggattg tagtatctaa atgctaattc attgtcagat tttactcctt
     7261 caaattttat ctgtcctatt cctttaaata tttcactcat ttcatgtcct cctaatattt
     7321 tacacatata atatatgtag tatgttttct taatttaaaa ctattttcta tctttatttt
     7381 tctttttaag ctaatttaat tatttatttt tgcattaact acttcatcta ataacttaaa
     7441 gtcatctttc aaagatttgt atattctttt atacaatcta tgatatatat tgtatgtatc
     7501 tacattttca cttattggtt ctaatttagt tgaagttttt attatagcat cacaagcttt
     7561 ttgtatattt tcatatattc cagctcctac taatgcaaga attgcaactc caagtgctgg
     7621 tccttcactt gaatttatag tatatacatc ttgattaaac atatctgctt gcatctgtct
     7681 ccatacttta ctttttccac ctccacctga ggctcttact tcattaacgt ctatattaag
     7741 attctctatt atatccatac agtctttaag actatatgaa acaccttcca ttattgacct
     7801 tgcaatttct tttttagaat ggattggaga taatccaaag aacacacctc ttgcataagg
     7861 gtcaagatga ggagttcttt ctcccatcat atatggtaag taaagcaatc cattacatcc
     7921 tgttggtact ttacttactt gattatttat aatctcatat acatcttcac ctaaagaatt
     7981 tgaaacttcc acttcacttt gacagaaatt atctttaaac cattttaatg acaagccagc
     8041 tccttgagta actcccataa catgccatgt atttggtatt gcatgacaga aagtatgaac
     8101 tctaccttct ttatcaattt ttggctcttt tgtataagca aatactacac ctgatgtacc
     8161 tatagtagat gaaactactc catctttaac tattccattt cctatagctc ctgctgcttg
     8221 gtctccagct cctcctacca ctattgttcc ttctttaagc cctgtcaaac ttgatacatc
     8281 tctagtcaca taacctgtaa tctcttgtga ttcataaact ttacctaaaa gatttttatc
     8341 tatatttaac ttttctagta cttcatcgct ccaatctctt tttcttatat cgagcaactg
     8401 cataccactt gcatctgata cctctgtagc atattcacct gtcaatttgt atcttatata
     8461 atcttttgga agaagtattt tattagtatt tttatatata tctggttcat tgtttctaac
     8521 ccataatatc tttgatgctg taaatcctgt aagtgctgga ttagcagtta tttcaatcag
     8581 tctttcttca cctactaaat cagttatctc ctcacactct tttactgttc gttggtcaca
     8641 ccatattata gagtttctca atgttttacc ttcattgtcc agcataacta gaccatgcat
     8701 ctgccctgat aatccaattc cttttataca ttcactgctt atatttgaac tttgaactac
     8761 ttctcttata gattcgacta cagctttcca ccaatcattt gcatcctgct ctgcccaacc
     8821 tgatttctct tgtataagag gatattcata tgtacaactt tttatagtat ttcctagttt
     8881 atcaaataaa actgttttcg tacctgatgt accaatatcc acacctaata catactccaa
     8941 cttcatccct ccttgaatgc cacttcataa ctatcgtttt cctatcctaa tttttttata
     9001 ttttaggtat attttacttg ctttattttt gttagtatat taaactaact tatgaactaa
     9061 taataaaata tttaattatc tttgtcaatg caaaataacc ttttattttt gtgtaaaaag
     9121 tattacaata ttattttaag gaggaatatc aaattggtta ctgataaata cactattcga
     9181 gaaatgaatg aaagattggt acttgaacaa attataaaaa atggtcctat ttctagggca
     9241 agtatagctt ctactatagg attgaataaa gcaactatat ccgctattac caaaaaactt
     9301 attgatgaat ctctagttca tgaaatagga attggaaata gtactcatag tggcggaaga
     9361 aaacccatat tattagtatt taataaatgt gcagggattt ctttaagtat ggacattgga
     9421 tacgactata tattttcttc tctatcttac ttagatggaa ctattataaa ttctaagaaa
     9481 ttaacagata tacaagtaag taaagacaat gttatacaat tgatagatga aattataaat
     9541 agttataaca tatccaaaat agacactcct tataaggtaa ttggtcttac tttggctata
     9601 catgggatta cttgtgaaaa taaagtattg tttactccat attacaatct taatgagatt
     9661 gacttatata gcatccttag caaaaagtat gactttccta ttcatataga aaatgaagca
     9721 aacttaacag ctttagctga gaatactttt tcaactgtac ataactcact acttagtctc
     9781 agtattcaca gtggatttgg ttcaggcatt ataataaata ataaattata tagtggcaga
     9841 aatggtatga gtggagaaat tggtcacact atcatcatgc ctaacggtaa actatgtcct
     9901 tgtggaaatc gtggctgttt agaacagtat tgttcagaaa aaaaggtatt tgaacagctt
     9961 tcttctttag aaaatattcc taaaatagat tctgatatag taaagcaact atattatgaa
    10021 gataaccata atgccaaaaa agttattcat gagttttgta gttacttaac aatagctata
    10081 aataatgcta ttacaactta tgctcctgaa ataatatatt taaatagcca aataattagt
    10141 gatatccctg agatattaca gattacaaaa gatatgttag ttagctcttt taacaaagga
    10201 ataaatatag aaatttcatc attagggtct gaggcatctc tatatggtgg ctctgctgta
    10261 aatatcaaga gctttttgaa tatacaaaat ttaactttaa ttaatgaaat ataagggtta
    10321 tgactatata cagccataac cctttaaatt atacattcta aaattagatt tattatatag
    10381 tttatgcaag attagctata ttttttaaaa attgtatatc aattaagtat taacataagt
    10441 atttcgtttt aaatattaat ataatcttcc tactcatcat cagataataa atttgcattt
    10501 tgttcaacca tagaaatatt atctttacct attttctcta attttgctgc caattccttt
    10561 gtatctaaaa aagctgattc aataaccata cctaaattta gccctgaaat aattttaatt
    10621 cgactgtcat tattggctac taataaagca gcattgcatg gagttccacc tagtaaatct
    10681 gccattataa ttatttctga actttccttg tacacttcta aagctttttt taatttttct
    10741 attgttcctt ctattccatc atcttgtttc atatttacag taggataatc tatagaatcc
    10801 cctattatca tttttgcaga atttaagact tcttcagcca tattgccatg actcatcaaa
    10861 ataatactat tcaatttaat acacctcttt aaatctataa gatgtctaca agataagttt
    10921 tcttatcatc aggcgtcatt atagttgtaa tttcaattcc ttcatctaaa agtcttttaa
    10981 atgcttcttt ctcttcttca gtaacactga tattaggtct tagaactgtt gtatcttttc
    11041 tacttgacat atttcctaca tttatattat gtattttaaa tcctgcctct acaaatggaa
    11101 taaggtccac aggagactta acaattaata atacattttg tccttcatac tttcctgcag
    11161 taatattttt tatagcagtc tcttctgtaa ttatagatga cgctatacct gcaggtgtag
    11221 ccattcttaa aacttgtttt tgaacagaat tgttagctac tgcatcattt actaccatta
    11281 atcttgtaac acccaattta ttactccaca tagttgcaac ttgaccatgg attaaacggt
    11341 catctatacg aatattttta atacctttca tttccatatc taatatcatc ctttccttat
    11401 tttaaaatac ctaatgcata taaaattatt gaaacaacca ttactcctaa aattaagtat
    11461 ataggtttta tattcttttt aagagcccaa taaacaatca caactaaaat tgcaggaact
    11521 aacccaggca taatttgatc taatatttct tgacctttca ttgtaaaatc accttgttga
    11581 aagttcaaag caacattagc ttttacaact gaaggtatta atgcacctac aaccattaaa
    11641 cctaaaatag atgtactctc agttaaaatc tttaaacttt tttcaattga agatattagc
    11701 ttagtacctg atgtataacc agcattaaat agtggtatac ttaataattt caatgctaca
    11761 ctcactacaa tccacagtaa gattccaaat ggacttccat ctatcgccat attagctgct
    11821 atagctccaa aaattgtcca cggaataacg acaaataaac tatctcctaa acctgctact
    11881 ggtcccatca agcctgtttt aattgaagca acagcctctt cagtctcttc acttgataac
    11941 tcctccattg ctacattaat acccaaaata taaggggcaa cccaaggatt agtgttaaaa
    12001 aattgtaaat gatttaatac agcactttgt aacttttctg gattatcttt gtatactact
    12061 tttaaaaaag gtagtactgc ataacagtat gccaaggcct gcatcttctc ataatttgaa
    12121 gaaacagaac tagtaaaaaa ccagcgccat aagacacttt ttttcacctt ttcatttgat
    12181 ttatttaatg ataccttatc actcatcttc gtccatacct cctactacag tatattgttg
    12241 ttcttgattt tccaaattct ttttgtaaat tataagtgca attgctccac caattaaagc
    12301 tacacctaat aatggtactt tcatatatac tgctaaaaca aaaccaatta ctaagtaact
    12361 aaaatactcc ttagcaggaa gatatctaag taataatcct atccctactg ctggaagtag
    12421 tcctccagct actgttaaac cacctgttaa ccattcaggt gtatatttca aaatggtatt
    12481 aattaaagaa ggtccaaata ttacagatag agcaactgga atacctgttg tagctgctgt
    12541 taatagtact cctaacattt gcatataggt tatattttta taatttcctt ttttagctcc
    12601 atcttctgct ttatgaacta gccatatacc aatagtattt ctaagaacat ctaattgtac
    12661 catcaataaa gcaactggaa tacctataga gattcctaca gatgcttctt gcttagtcgt
    12721 aatagttata aatgtggcta ctatacttgc tgtttgataa tcaggtattg atgctccacc
    12781 aaagttacta atacctaatg ataatagctg taatgtacct ccaatatata accctgtatt
    12841 tatatctcct aagataagac cagtaataaa acctgctgtt actggttgat atgttccaaa
    12901 cattgttgaa tttttttcat agtttataaa aaatccatat agtacgatta ataataattg
    12961 ccataattgt ggctccatta tgatttcacc tctcccaaaa tattttttag ttctttaaaa
    13021 ttataactgg aatcttgctt taggaaaata ggaatttctt ccagtgggca ttcaacttca
    13081 taagttttcc caccttcata actaactcca ctaaatatat tttcccatgt atgtcctttt
    13141 ggtaaatata cttttctact tctatcttta taattcatta ttggagctac taaaatttca
    13201 tctccaagca tatatgtatt atccacctcc caagttttat catcttcagg aaattcataa
    13261 aataaagttc tcataactgg tgttccatct tcatgcgctt ctttcatcag tttttttaaa
    13321 taagttttta agctctctct aatttttatg aattttgtaa gaattacttc aacttcttca
    13381 ccataagacc atatttcatt aggagctcca gttaccattg agcctccacc tttatttgat
    13441 aatggtttac tatgaggcaa tctatctcca tgcattctca aaattggtga aaaagtagca
    13501 tattggaacc atcttaccat aagttctcta aattctgggt ctttaggatt tcctccatgg
    13561 aaacctccaa tatcagtagt ccaccatggt atacctgcca gtcccatatt taaccctgta
    13621 tttacttgat tattaaaagc ttcaaaacta gaatcaatgt caccagacca tactaaagct
    13681 ccatactttt gagctcctgc ccaagctcct cttacaagag ttacaacaga ctctatgtca
    13741 ttatgtaaac catcataaat catttttaaa taatcaatag gataaatatt accacaactt
    13801 aaaacatttc cttttttata tctatagtta tcaaaatcat acacagaata gccaggttca
    13861 gctacatcta accaataata gtcaatccca agttgtttat aatttttatc tattctatcc
    13921 caaacatatt ctcttgcatt ttcatttgtc atatctacaa agactgtatt tccttgaatt
    13981 tgcattgtca ttctaacacc acgattaaca ttgactaaat agccattttc taaataatca
    14041 ttgtagtttt ctgcatcact ttgaactgta ggccatacag atactattgg ttctactgaa
    14101 tactcttctt tcaatttttt aactaattct ttaggatttt tccaataatc taagtcaaat
    14161 ttatattcac cttgcttagg ccaatgaaaa tagtcaattg caattgatga aagcttaatt
    14221 cctcttttag aatattcctt cacaacatct aaaacttctt ctgaagttct atatcttagt
    14281 ttactttgcc atagtcctaa aaggttttca ggcatcatag gaacagttcc agtaacttga
    14341 gagtaatttt tatttaactc ttttgggctt tctccacaag taatccaata atctataaaa
    14401 tttgtagaaa acatcttcca ttctgtcata tttttagcaa aagatacttt tccaattccc
    14461 ggattattcc ataaaagtcc ataacctaga ctagaaatat aaaaaggaac tgatatttga
    14521 gaatttcttt gggctaactc caaaacagta ttctttaaat ctaaaaattt atgttgatat
    14581 tgtcccattc caaaaatctt ttcagaaggc tcagattcaa atctagtagt tacttcaaat
    14641 tctccactat agcttggtcg atattctctt gattttaact ttagagtaga gttaaagtct
    14701 ttggtaatct caattgtccc tacatcttct ccaccatcat catgttttac agctcttaat
    14761 cgaatatatt ctttcaataa tatttcattt ttatcattat aaaaagtaat tctatctcta
    14821 tggtctaaga cagcttttat ctttccattt ttaatgattg cacttccatc ttcattttta
    14881 ttaattgtaa tatcatcttt atttaactta ggtttttcgt taagagcata gttttcatca
    14941 acaaaatttt ggtctacaaa cgacctaata cgtaaagagt tttttcccca tgcttctatt
    15001 cgcaatagtt cattgtcaaa tcttttttca atatagtctt cagatatttt tatcacggct
    15061 acctcctaaa tcaatggtat aatattctat ctttgtgtaa cttaagttaa ataatgtcgt
    15121 ttagtatcgt tatttataaa ttaggtttta tatataattc atttgtacat taaactaact
    15181 taccaataat atactttatt tgactttgtt tgtcaatcgc tttccggatt ttagtaaaat
    15241 tttctaatat attgctggaa agttgttctt aatatctttt atttatactt ttaatatctg
    15301 tgatgatacc tatatacatc tagttttttt aaaacacata caggaataac atttgcctat
    15361 tatgtagata atatcggact tgaaaatatg tatagtgacc ttataaatac agataataat
    15421 atattagata ttgttcaaaa caatggattt tataattata aataatttat gaaattattt
    15481 aagaaaatat acaattgtat accaagtcaa aaacgacaac aaataaataa aactaaaaaa
    15541 gatgttgtct caaaatatag ataaatttat ttttcattgc taaaatgatt aaaatatatt
    15601 tgatttaata tacttgattt aatataaaaa aagagtgtct cataaactaa aaagttcact
    15661 tttagacact cctttatata tattatctac ttcttaattc atttattacc tttctacatt
    15721 ttctttcagc tagtggatac atctttataa gtactaatta ctccacttaa aaatggttcc
    15781 tgtactgtcc atcagtcata tttttctgcc aaatataatg gtgtttcata atgagacaat
    15841 aaatatttat atctctactt atcttctcta agctcgtcaa atccaactat aggtatctct
    15901 aaattatatt ctttaagtag cttttctagc tcttctataa aaataccttt cccatccacc
    15961 atttgtatat cctttatttt atccatcaat tcattgcaac cacttaactc accaaaccaa
    16021 cgtttagaac tacatgtctt attataacca caacttggac tgccatctat tgcaatgata
    16081 ctttttatat cataatcatt ttttaaatat tcatcaaact gccttacatg aggtattaac
    16141 atttgcctac attgttctct aaaaaacaaa ttgtcaaact gttcttttac atgtccccac
    16201 ctatttattc catacataat catttctggg catggtagtt gaattattcc atacccttta
    16261 tttattaaat ttatcgctat attttgtgct cccttaaatt ctgacaatcc ctccacttta
    16321 gaattacaat ttaatataca atgacatact actacaatct ctctatttct tttcataata
    16381 atctccttag ttattcttaa ttttaatgat actacatatt ttgataatta tattatttat
    16441 ttgttctata tttccaatat tctatataga aatatacaat tagtaatctt ttataatcta
    16501 tactatgata aatgtatata tttttttagg aggtattata attggatact aaaaaagtca
    16561 cattttcttc aatgtgcata gttattaata ttgtcttagg tatggttata tctatgataa
    16621 atataccatt attattttta gatacagttg gtactgtact tggggctgtc gtattaggtc
    16681 ctttttgggg tgctcttatt ggtggatgta caaacttagt tttaggtgtt atatcaggtc
    16741 ctacaaatat accttttgcc cttgtaaata ttgtccttgg tcttattgtt ggatatattt
    16801 ctaagaaaaa aggttttggt tataaagaag ctattattac aggagtaatt ttatctattg
    16861 tttgtccttt aattggtact cctatttcag ttttattgtt tggtggttta agtggaagtg
    16921 gtgctgattt attggttggt tttttagttc agtctggtca gaagatattt actgctgcgt
    16981 tctttccaag gattcttagt aatatagtag acaaaccttt gtcttgtatt atggtggtat
    17041 attttataag taaaatgcct aaaggtttta taaaacaata tagtaaaaat acttctagtt
    17101 catattaata aatcatttat tatgtaaggt ttattactct ttaaaatgct atatactcat
    17161 ttttatataa catttttatt aataatttaa ttagatagta tttgtattac tttaattaaa
    17221 cgtaacctct tgatataaat ttgagctata aatctatatc aagaggtgct attttatttt
    17281 taatataatt aatattctat tacgcaaaaa atgcatatat ttcattattt tatggaaaat
    17341 attacttcat ttaactctat atcaaactca ttaagtaaaa atctaattat atttaattta
    17401 gcctctgtat ttaaatttgt ttctaaatat atattttctg atattttaat accttttctt
    17461 aatttatatg catctctaga cttaatatta tctataaaat ctcttttata agttttgtct
    17521 acaatactgt taaaccttac agaatccaaa tcatataaag taagagcaac ttgttcataa
    17581 aattctgtcc aatttttagc cttatatgac tctcctaata tactaaatga tactatactt
    17641 tcatttgtaa aattaacatc atcatcctct aacgtaaata tattttcact gttacttgga
    17701 ggttcatatg taacacttgg atatttccaa atttctacag ctctatctag taatatctta
    17761 gttctatttt ttatttcttc ttcattccat ttatctatag atgaaatata tttatttaga
    17821 taaagcctac tatctttaaa tccatcttcc atttctttct tttcttcaaa tgttttatta
    17881 cttagttttg aattatatcc tgtcaaagtt aaatttccaa ttgtatgtaa atatttatca
    17941 tgtatctcct tatagttatc tcctagtgat tccttccatt tatttgttaa tgtctgtggc
    18001 attatatgct ctatatttag catattatta ttgattaaat tttctaaatc aacaatttct
    18061 ttattactat aattctctaa cctctcaagt atatataact tattctttga cttagtatta
    18121 tatatatctt tagtttcaaa agcatttgaa aattcactgt cagtaggaaa tctttgagat
    18181 gatttcttat ttataaaaat atatcttaat atattagaat agttttcttt ataatcacta
    18241 aattttttaa tttcccttcc taagttcata aatactttat tcagtgcatt cggaggtaca
    18301 tcacatacta ttcttcttaa tataaaacat tctactaaat taagggattc tacaagtact
    18361 tttttattta ttataccttc attataatca tcaaataatt ctaatataaa cggatatgat
    18421 acaaatattt caagtttgtt tatccttttc aaaactttgt ttacatcatt atcatcagta
    18481 catgaataag atatctctct ataatagtta gaaaatttaa gtaaatcttt taataaaatt
    18541 tctatatcta taccattatc tgatacatac cttttaaaac taaaatatac tttattttta
    18601 ttcggtatac ttctctcctt tatagtcaaa tagtctctta taaaactact tacgttgcta
    18661 cttgtatttt tttcaatttt ataccaataa ttattataaa attcctcttg taacttagag
    18721 cttctaccca ttaacacaaa gtttcttact ctatcagctt cacttaaatc taagccagtt
    18781 gaatttagac tttcaaagat taattgaggg tcatcttcac cattttttaa ctctatttct
    18841 actatagtta atttctgtat agcatcaaac aaatcatcta ttgatatatt atcttctttt
    18901 attctattat aaaaatataa ataatttgaa actatattag aatttctatc tgtattcatt
    18961 tcttcttcaa atagttcata gtacgctttt ctatcttctg ctattggttt taactttatt
    19021 tttccatctt tatctcttga gtgcttgttt ataagataac actccttaat ctgttcttct
    19081 gttgtaataa ttccttttga ttccccaaac tcttttatta tttgacacat ggcaatcaat
    19141 aatattgaca cagtagtcac tctttgttgt ccatctatta ttaaatattc ttttcccata
    19201 ctatatatag atacaactga ccctaagaaa tgagttctaa atccagaatc tattatatcc
    19261 tctaaatcat caaacaatct tttacattgt tctttcttcc agttataatt tctttgatat
    19321 acaggtacta caaaactttt gtttgacccc tctaaataac taagaaattc aatttctcct
    19381 gctttcatat taactccccc tataagttaa ataaattcca ttcataactc catgtatcta
    19441 tatattatat caaaattttg actcataaat gtatatgaaa gccttattat ataccttttt
    19501 atacctgttt ttattttatt aaagtaaata catgattatt ctataaaata tacaaatact
    19561 taattttaaa aattattatt taatcttctt catgagtaat tcatagttat ttatcaatta
    19621 aaaagagata ttgcataatt attcaatacc tctctttgta tatttacatt atccatatct
    19681 agttatctat ttcaacccaa tattagacta cctactaata aatttattct ctacatcatt
    19741 aacaataatt ttgcactaaa taacatcatt agcctatctc tgatgcattt tctttaattt
    19801 tatttatagt tttaatcaat ttatttctct cttcaatatg attttcaaat aaatcaatta
    19861 tacttccaac agttctaaat gggtcttcca tcaacacttt gttatcctct ataaatccat
    19921 tcttgactac ataatcgact ataagtttaa caaaatgtat ttgcttagta ttaaagctct
    19981 tattatttaa aaactctgaa aaagcttcat ttgcagcttc tctatccaat cccactagtc
    20041 ttctcactaa ttgacttact ggagtatctc caaactcctt cttataatca tcacaattac
    20101 ctaactgttt taagagtatt tcctccaacg tttcaacatc ttgctttgtt atctttttat
    20161 tatttcttaa tttaaatatt gctaattcat ctttatggct atttaaataa tactctacct
    20221 tctttttata attcttaaga ttgtttgcat tatatacaga atcatttcta tcttctgcta
    20281 caatcatatc ttcaaaactt gtataatata tcttttgact agacttttca agatacttaa
    20341 taagctctct taatgatata cgtacttctt ctacctcaaa tatatctgaa tcttcccaaa
    20401 aattctctgt cattgctttt tcaatagtat atttttgttg ctgaatctgt ggtatagtcc
    20461 caagttttga aagtttttct gctgtagcca ttacatgcct tataccttta cttgcattat
    20521 tattttgtaa gtatgcaagt tgtatattat acataactac atcaaatctt ttagccaatt
    20581 catcatcact atatgaagtt atgagtggtg atatatattc tcttatctca ttttgtgcta
    20641 ctgctccaat attgctccaa acattttcat ttttatactt atgtacataa cttaaattca
    20701 tcctaactat ataactatcc tcatttaaag cttttacaga agttataagt tcttctaaca
    20761 attcttttct aagttctgca tactcacctt ctatatattt aatatcttga agttctttaa
    20821 ccatacttac ctttatatta aataattttt cagtaagtgt ttctgcttta tttccctcaa
    20881 atcctttagg attaaattta aaaaattcaa aattattaca aaaatcaaat attaagaatc
    20941 tctccttatc catatcaaca cctaataaat ctggacataa tctagttcct ctacctatca
    21001 tttgccaaaa cttagtctta cttctcactt tcttgaaaaa aacaagattt agtatttcag
    21061 gtatgtcaat tcctgtatca agcatgtcta ctgaaactgc tatttgaggt aatttattct
    21121 tatcagaaaa atcatctatt atagaatcta cataatttat actatagtca actgctttta
    21181 caaagttccc accatacttt ggatacagct tattaaatct ttcaactatt gccctagcat
    21241 gctttgtatt ctttgcaaaa attatagtct taccaatctt ttcttctcct tctattttca
    21301 acccctctgt cattagctta tttaaaacta aatctattgt gtcagaatta aatagccact
    21361 catttactgc attattccct atttcgtctc caatactctc atcatcatta aatgtatttt
    21421 catattcttc cttctcttca tcagaaagct catcatactt aattccatct tccataatct
    21481 tagtcttaaa ctcaatacta gtataatcta ctaaatatcc atcctcgact gccttattat
    21541 actcataagc atatgtaggt actccatttt ccatgtcaaa aactgaataa gtatttttat
    21601 ctatctcatc ctttggtgta gcagtaagac ccattaagta agaatcaaaa taatcaaaga
    21661 ttgacttata ctttttataa atacttctat gcgattcatc tattataatt aaatcaaaat
    21721 gaccaggtgt aaacaatctc tttccatcct tagacttcgt atcatcaatt gcattcatca
    21781 ttgttggata tgtagaaaat atcatcctag catcttctgg gctgtctttg ctatccaata
    21841 aattacataa cgccaagtta ggtaatagct tagtaaaact ttttttagct tgctttacca
    21901 atgcttttct atctgctaga aataatatat ttttaatcca attatgtctt gaaagtacat
    21961 caactataga tatagcaatt cttgtttttc ctgtaccagt agcacatacc aaaagagttt
    22021 tgcgttgctt attttcaagg gcctcacata cagcccgaat agcttctttt tgataatatc
    22081 tattggatat ttcatcattt attgttacag aacttaaaga cttcttactc tttcttctat
    22141 ccatcataag ttgtaattct gattttttat aaaatccata aacttttcta tctgaatagt
    22201 catcccaaat atacatatca aaaccattag tcaaaaatat tactggtctt tgactatatc
    22261 tcttttccaa acaatctgca tataatttag cttgttgttg accaattttt gggtctttgc
    22321 tcgttctttt cgcctcaact actgctaatg gcttaccatt ttcaccataa agaacataat
    22381 ctacatatcc tacaccactt tcattaggca taccttgtac ttctatttcc tcccctatat
    22441 cttttccaaa ttcccaacct gcaagcttta attctatatt tatatatctt tttcttgtct
    22501 caaattcgct tacttcgtct atcttgaaat catagtttac agtattaact tttctctttt
    22561 cagttagtga ctttcttaat tcctcatttt cttttattac ttcttcaagc tttttatctt
    22621 ttgaacttaa tctctcgtaa agatttttaa gttcgtctgg tctcgtcctt ttctcttctc
    22681 catgaagtaa taaatcttca ttaaagtctt ctgctgtata ttcatctgaa taacaatagt
    22741 ctatccaact aacaaattga tgcaaattgt taagtgaaag tattgcttct cctctctcta
    22801 tgttcgcact agtatgtaca gataaattac ctaacttaac tatatatttt aataaaggta
    22861 acatatcata gtctataagt tctataaaac tattattatg aatcaacgta ctgagattat
    22921 cttgataagg caatactaaa tcactatcat tagcatatag ccattttact gcaagctcta
    22981 aagctcttct tgttatagtt gcacaagtag atggactaac tagtatactt ttttctgctt
    23041 ctaagcaagc agtattaaaa ctattgaaat ttttcttctt ttgtaaaaaa tcaaaattac
    23101 ccaaggcttt tatccccctt ttgtccctta gttaaaataa atctctctaa aaactatttc
    23161 ttacagctgt ttcttatact aacaaatact tcttcatttt ctgtaaacaa ttcgtacata
    23221 tcttcaaact gtggtatatc atatccatga gaatcatcat ttctcaattt tctaagtgtt
    23281 tctataacta tagaagaatt tttaggtaat aaattgtgat actcacaagc taaaaggtag
    23341 tcataaaagt ttttagattt tatgtttaaa tcaattgatt tataatacaa cattgctttt
    23401 gttaattcta gaaatgatac catatagctt ttaaagcctt cttttatgta tctagcccat
    23461 aactcaggca tttcttcctt atcatataag attttgaagt tttgcaggtc atacaagcaa
    23521 gaaccaaaat ccctatttac ttcttctatt gagttccaag ataatttgtt tctaattacc
    23581 atacatgtcc ctccaatcta agatatctat tacatcactg ttttcaaaat agaatttatt
    23641 tatataatcc ttaaaatctt tagattcata aataacttca ccttctaaaa tagctttttt
    23701 aagtgctatt gtataattat ctgtaacaat ttttaggtct acatcaatgt ctaatatatt
    23761 tcttagagct tctgtcttag ttgcaagttc tgtaattggt acttttttga tgggaatcca
    23821 agctatgtct atatcacttt ctgatgtatg tttatctgtt ccataactac caaatattat
    23881 gattgctaga gtattttctt ttggaaatac atttattatt gagtttttaa tctcatttgg
    23941 tatatttctc atttaatcac ctcttgttta ttaggtaata ttgtttagtt aaataattct
    24001 cctttgaaag ctttttgcat taatgaatta aagttatctt ctaactcttt taagttggtt
    24061 tctattttta attttaattt atccacttgc ttaacaaact cagaaaactg attttgaaat
    24121 tcaattggag gaaccattat taaatattca cctaacttac taactgataa ctcaatttga
    24181 ttcgttgaac cattaacaca ttttctatat attgtgtctt gtatatttgt aaattcaaat
    24241 aacgctgcaa aataatctga atttaagtta tttgaaatac ttcttaaaac tgtaacatga
    24301 ctatctgcta tatattcaga attatcaatt ttgttaaatt ttacacatct tcctaatgtc
    24361 ccagttccag tagaatttat taatatatca ttttgtttca aaaatatatc ttctatcttc
    24421 tcttttaagt tttcatcata atatttacaa ttttctacct tcaaatttct ccagtatata
    24481 catttttgat ttataacttt tatatttgat tgctctacat atttaggaga tacacctctt
    24541 tttaaatata tagaaatctc tttaatcttc ttcatatcaa atttttttgt attattaatt
    24601 ggctccccaa acatctcaat aaatcttgat ttaactaatt catccaatgc ttctatttgc
    24661 tcttttcttt tatttattaa ctcttgagct ttatttaaaa cttctaccat tttattttgt
    24721 atacaaattg tgaaatatgg tatttttata tcatttaact tgcttttatt taaagttgca
    24781 cccataactg ctctatcagt attattaaaa tttaaagttc tcaaagcata atataaatat
    24841 tcagatgtta taagttcatt attttttatt tgaaagttag caattgcttc atttgtaaac
    24901 atgtcttctt ttaatatggc aactctacct atagacaact taaaactcat tacaacggta
    24961 tttttaggta ctaatttcat attagctttt tcaacagcta aatctgttat ctcttctttt
    25021 gattttgata tatatttttc tttcaaatca gaaattgata accatctatt accacttccc
    25081 caataatcag aagtatttct agatggtgtt ttgccaatat ttatatagca caattcattt
    25141 aattttatat actccatacc ctatacctct aacattcttt ctaattcttc taatccaaca
    25201 gctatttcct tctctaactc cctaactcta cctataatca cactaggagc atcataaact
    25261 acttcctcat acactacctc tttatactta ttaatagata aatcataccc attctctctt
    25321 atctcttcca catcaacaaa aaagctttgt tctgttcttt ttctatctac ttccccatca
    25381 agattatcaa atctcttaat aatatcctct atatcactat cctttatctc atttctctta
    25441 tcatccaaag aataaccatc agctttcata tcatagaacc ataccttatc agttccacct
    25501 gtccctgttt tagtaaatat cattatagct gtagatactc ctgcataagg cttaaacact
    25561 ccacttggca ttgatattat agcttccaat ttatgattat caactatttc ttttcttatc
    25621 gatttatgtc cacctgttga accaaacaat actccatctg gcactataca tgcgcatctt
    25681 ccaccaattt ttaaaactct taaaaaaagt gccaagaata ataactctgt tttctttgtc
    25741 ttagtcactt ttaataaatc tgctgacact gcttcataat ctaaacttcc cttaaaagga
    25801 ggatttgcta acaccaatgt aaacttatct ttatctgtat taacctccga taaagaatcc
    25861 ttatactcta tattaggatt gtcaacgcca tgcaacatca tattcatagc acctattcta
    25921 agcatagttc tatccatatc aaatccatag aacataccat tattaaaatg ctccttcagc
    25981 ccttgcacta agaaaagact tgaatgatta tcccttaagt attgttgtga tgatactaaa
    26041 aaacctgctg aacctgctgc cgggtctact ataatatctt ctggtgttgg tttaataagt
    26101 cttactatca tatctattat gtgtcttgga gtcctaaatt gaccattagt acctgctgta
    26161 gccactttgg ataataaata ctcatacaaa tctccctttg tatctctatc cttacttaat
    26221 tctaaattac taataccatc aactatttta gataacataa gaggcgtagg aattttaaat
    26281 attgcatctc ccatgtactt tgcataagct gagtctttat ttccatgtaa tttttttatg
    26341 aaaggaaaca cttcattttg tactatttca tacatttttt ctgaatttcc ttcattagaa
    26401 aacttactcc atcttaaatg ttgatgttca tcatcaaata tcctttcaaa agaaactccc
    26461 aaaagagttg cttctgcttc attttttgtt tctacttcat ccaatccttt aataaataaa
    26521 agatatgtaa attgttctat aacttctaat ggattagtta atccaccagt ccaaaatgtc
    26581 tcccaaatct tgtctacttt gctccttaat tctcctgtaa tcatatatga ctttccctcc
    26641 agtgttcata aaataattta aatatatatt ttagtcgtac gccttaataa ttagtgtctt
    26701 atattaaatt caaaatttta ctacacagtt attaaattat ttttcctatt tacatgtttt
    26761 agttaaaaaa ctaatgcaat actcttattt tatgattatt atacatccca tacaaaatta
    26821 ttttatcata tatccagcat agaagtcatc tacctggata actcttacca tattataact
    26881 ttttaatatt aatttaaact tagaaagaaa ttttttattt aattatatca tcttccttat
    26941 ttcaaatttc tcaattacaa tctcaatcaa aaaataaaat aagatgctgt ctcaaaatag
    27001 atataatctt cttttttatt ttcggaatga tgaaaatata tttaatttca tacaaaaaag
    27061 agtgcctcct gaactaaaaa gttcattttg agacacccct taatttaatc ttacttattc
    27121 tctcccttta ttattaacac ttcactatct ctattgcttt tcctacacat ccacaaactt
    27181 ccatcctact cttaacaaaa tctttaactg actctaaacc ttttttacca tatttcttag
    27241 ggtcaattac ctctgggtca gaattaagca catccttaac cccattgcta taagcaatcc
    27301 ttaattcagt tgcataatta accttgcaaa tccctctttt tatagattcc ttaataactt
    27361 catctggtat tccagaccca ccatgtaata ctaatggaac tgatacaaca tctctaattt
    27421 cagataatct atctaaatca agctttggct ctcccttata taatccatgt gccgtaccta
    27481 ttgctactgc caaagatgat acccctgttc tctctacaaa ctcttttgct tctaatgggt
    27541 ctgtatatgc tcccccatca ccaccatcta aatcgtcttc cttacctcca actttaccta
    27601 attcagcttc aacaggtata tctgaaggca tacatgcatc tacaacagat ttagatattg
    27661 aaatattatc ttcgtaactt tcatgagaac catcaatcat aatagaagta tatccaactc
    27721 taagtgcctg catagctagt ccaaagcttg aaccatggtc taagtgcatt gctactggaa
    27781 cacttgcctt ctctgatgct acctttacat tcgctaaata ataatctagc cctgcatact
    27841 ttattgttga aggtgttgtt tgcaatatta ctggtgattt aagttcttca gcagcctcta
    27901 ttactgccat aaccatctcc atattttcaa cattaaatgc acctactgca taatgtcctt
    27961 cttgtgcatc taataatatt tgtttagttg tcactaatgc cataatttct cctcctatat
    28021 gtttatactg atttgatttc ttcgttattt aattttgcta ctatttctct acttgttttg
    28081 ctatttaata actcatttaa aaattcttca ttcattaatt ttgaagatag ttgagataat
    28141 gtttttaagt gtaaattatc accattatct gtagctgcta tcataaatat aatatgtgct
    28201 aagcttccat cttctgattc aaagtcaaac ccttcttttg atacacctac tgctacacgt
    28261 ggtaccttta ctgcatctgt ttttgcatgt ggtatcgcta tccccatacc aaaacctgta
    28321 gatgatattt cttctctttt aaggatttct tctttaaact tctttttatc taaaagaaca
    28381 ctagatttat caagtattcc aatcatttca tcaattacat ctgttttatt ttttccctta
    28441 acatctaaaa ttactgtttc ttcgctatat aaagagatat tattagatac gttttccgat
    28501 tctgcacttt catttttatg ttcatctttt gttacatttg tattttctat agtatttttc
    28561 tcatttacta ctttaggtgt aaccatcata taaagtacag cacctactaa tgaacctaca
    28621 aatatacacc ctacccataa aagtggctta ttgactaatc ctagaaccaa aaaccctcca
    28681 tgtggagctg gtacttctat tttcattata taagttaaaa ttgatgatat tgatgatgca
    28741 atcataagta ctggcaacac ttttaatgga ttttttgctg caaaaggtat tgccccctct
    28801 gttatatgag tactacctag tatataattg attaatcctg ctgctctatc ttcttctgta
    28861 aatctatttt taaataaagt agatgctatt gctattacca atggtggtgt tatacaagct
    28921 gcagatacac ctgccataaa taaataattt ccctgtccta gaagcatagt tccagttaca
    28981 tatgctgctt tatttactgg acctcccata tcaaatgctg acatacatcc tattactatt
    29041 cccaaaatta tagggcttga attttgtaac cccgatagaa agttcatcat agcattgtta
    29101 agtgctgaac atggcccacc aagtaacaac attgctacac ccacaagacc tacgctgaca
    29161 ataggaatta taaaaatcga tttaagacct tctaattgtc gtggtaattt tcttaacaaa
    29221 tgtacaaata gtttaactaa gtaacctgct aaaaatcctg atatgattcc acctaaaaac
    29281 cccgaacctg tatcaaatga tatcattcct ccaacaagtc ctgctaacat accagctctt
    29341 cccgatatag attgagctat aaatgctgcc aatacaggaa ccatcaagtt catagaatat
    29401 ccaccaacag attttaatgt agctgctatt tgattatatt gttctgaatt tgggtcaaat
    29461 gaataaatcc cccataaaaa tgatatagca gtaagtactc cacctgctac tactaaaggt
    29521 aacatgtgag atacaccatt cattaagtct ttatacaact tttgaccaaa cgataaattt
    29581 ccttcttctg caattttact gcttgataag tttccttttc taatagctac ttttccatca
    29641 atacatcttt gtataagttc attagcttta tgtatacctt ctttgacagg tacttctatt
    29701 actggctttc cattgaatct gtccatatca acatttttat cacaagcaac tattattgca
    29761 tctgccattt cgatatcttt tgctgttaac ttattttcta cacctatagc tccattcgtt
    29821 tcaactttta tgtcacaccc taattccctg gctgaatttt ttaatgcttc ttctgccata
    29881 aaagtatgag ctattccagt tggacaacct gttaccccta gaatcatttt ctttcccatt
    29941 tttataccac ctttctgact cttatatttt ttatataatc ttccacattc tccaaattac
    30001 ctataccatt actttcagcc acacttgctc ctgttgctgc tgaccttttt aatgcttctt
    30061 caatatgttc tggattttcc aaccatatac ttaaaaaagc agctaatgca gaatcaccag
    30121 cacatgcaga gctgactact gtaactggtt gagcactagc ataataaatt gattttccat
    30181 tataaaaata agaacctttt tctcctaaag ttagcaatat attttgagca ccttttaaat
    30241 gtagtaattt aagtacatcc ttaatatctt cttcatctct tacaataatt ccaaatatat
    30301 ctttgatttc ttcatcattt ggttttatca aatatggatt atactgtagt aactccttta
    30361 attttggtga acttatatcg agtattgtct ttatactttt atttttacaa attttaaata
    30421 tatcctcata gtaattatca tcaataccag gaggtagact tccacttatt gataagtaac
    30481 ttatatctgc taatgactgt atcttatcta gcatatctag tttttgtttt tcatttacat
    30541 atgacccaga gtttacaaat ttaaattcat cacttccatc atttaaaaat atatttatac
    30601 gagttgtatc ttctacccaa gtaggcaata cgtcaaatcc tctcttttcg ctttcttcaa
    30661 ctatatattt tcctgaaaat cctccaaaaa atcctaatat cttagattct ataccataat
    30721 gacctagtac aaaagttaca tttaatccct ttccattagg agaatataca gcatttgatg
    30781 tacgatttac taattttctc tttatcccat tagtagatat attcatatct attgcaggat
    30841 ttgtagttaa tgtatatatc attgtcttcc cccttgcttg tgctgtgtat gttttcatta
    30901 taataaaaaa gtctatgaaa atcttttcac aaatagaaaa tcgattttca tagacttttc
    30961 aatttaattt tcagaattat tatatctgac catataatct ataattatcc tagatataat
    31021 atacaagggc aatctggaag atacttcata ttcagaaatt gatatatgtt catgtttgta
    31081 tcctacaata tataaatccg aatactttat aagttttgca ctttcactac aacagcaagt
    31141 tataacctta gctccaacta aattggcatt ctgtgctgat tctacaagct ctatggtatt
    31201 tccattcaat gaaaatataa ttataagttc gtcttttttt attgatttag attttatttt
    31261 cattatgttg gggtcattta taaaaacaac attaaaatca agtaattgca atttaagact
    31321 aaactctttt gctacatatt cagtaagccc tcttgctaaa atatatatct tactagattt
    31381 atttatagtt tttattatat tgattagtgt agttaaagat atttgttcta taactctctg
    31441 tgcttctata aaggatttat ttattatatc ccccatattt tgtatatcat cattttcatc
    31501 ttttactgtt aatctatacc taagttcatt gaatccattt aaaccacatt ttctaattgc
    31561 tcttgaaacg gttgctggag atgaatatgt ttcatgagca atctctacta tagataattc
    31621 tggtaatatt gattcatttt catttataaa tttaattatt tcaagttccg tcttcgttag
    31681 attttcagaa ttacttttgt ttagctcaat tatcatatgt tatctcccct tatataagtt
    31741 ttatttgtct aaatttatcg agtaatataa tatattacct cttaactact tatttttata
    31801 tacaattaag atttagtcaa tgtctatata tgtaaattta taatataata attttttgct
    31861 taaagtttat tatgttatct tatagcattt taaaataaaa aagaattgta cctctaccaa
    31921 aatttggatg aagtacaata gatattcctc atactgatat gtttatgatt aaaagtataa
    31981 atataaattt cgctatgaat catataatta ataaatcatt ttatttacaa ttataacccc
    32041 ccttataaaa ctatattaat aatatataca gtatttataa ggggggttgt ttatatttaa
    32101 aaactattta cttttctctt aattcttctc cattagttct tattacattt tgataccaat
    32161 aaaaactatc ttttttataa cgttctttac ttccatttcc attgttatct atatccacat
    32221 atataaatcc atatcttttt tccatttctt gagatgaaca acttactata tctattggcg
    32281 accacataca ataagctaat atttcggttc catcagctat agcttcacct atttgttcta
    32341 tatgttttcc taaataatct attctgtaac tatcatgaac ttttccatct tcaaatttat
    32401 catgcattcc aaatccattt tcagctatca ttattggctt ttggtatcta tcataatatt
    32461 gagataaagt attgtataat ccttttgggt caattgccca cccccaagga tttgctttta
    32521 aatatggatt ctttatattg tcagttggat tcatggtgtt tttacttgct gatactgttg
    32581 tagaataata gtatgataaa gctagaaaat ccatagtatt ttcttttaag attttatcat
    32641 caccttcctc cataactata tttatgttat tttctttgaa aaatctctta atatagactg
    32701 gatactctcc cctaaaactt acatcagtga aaaaatattg tagcctattt ctttttaaag
    32761 caaatactac attttcaggg tcacaatctt ctggataaga tgtacaatct gccatcatca
    32821 tacctatcat catatctgaa tttatttctt ttccaagctt cttagtcaaa gctgtagcta
    32881 tgaattgatg atgaatagct tgatatctag tctcttctac attatcaact tggtctacac
    32941 aaaatgcaac tgaattaaat gattcataat gtattaaatt tatttgattt ataactatcc
    33001 aatatttaac tttattttta tatctattta gtattaattc tgcatatcta acaaagaaat
    33061 ctaccacttt tctattagac catcctttat attttaatac taaattcaaa ggagtctcat
    33121 agtgaagtag tgttacaata ggttccatac cattatctat tacttcattt ataagattat
    33181 cataaaactt taatccctct tcattaggct ctaaatcatc tccatttgga aatattctag
    33241 cccaatttat tgaaaatcta aaacacttta accctagctc tttcaaaagc tttaaatctt
    33301 ctttgtatgt atgataaaag tctattccac tacgcttagg ataatatcca ttattatctt
    33361 tcatagcaaa ctttattctt tctatagtca tatcagactc ataaggttta gatatatctc
    33421 tatctttatc atacatatgt acatcagcta aacaccaacc tttgccacct tcattccatg
    33481 caccttctaa ttgattagct gctacagctc ctccccataa aaaaccttta ggaaacttac
    33541 ccaatttaat cactccttat tttatttatt taaatcattt actattattt accttatatt
    33601 ctatagactt tactattcct actaaagaca tagttatatt taactcgctg aatatggtca
    33661 taagagtatc ttgagcatgt gcaaataaca gcgaatgtgc tcttttctct ccaccagctt
    33721 ccccttgtat aatcttggtt tgagctctat gtgcttctgt cataaaccct tttgctttag
    33781 ctagttttaa atcagcattt ctataatcaa acttttccaa atcattaaga gcatgtttaa
    33841 tttctgttct agcctcacct gcacgaagta ttatttgcat tgctacttct actaattctt
    33901 catctattat atgttcttca attgtcatat ttataatttc ctttcaattt ctaaatttaa
    33961 acctcttgac tctctaattt tatctcttct ttctcataag ctttaaaaaa tggataccat
    34021 atcataaata gcaatactat atttattgct aaaacaataa gacctctaac atcttgattt
    34081 accataaaag tagatatacc aaaaggaaca taccataaat taaacacctt acttggaatt
    34141 gtaacaaatc ccatactcat tgataaataa gtagttattg atattactac tgttcctatc
    34201 cacataggta acattaaaaa tgggttccat gccactggag ctccaaatat tactggttca
    34261 tttatattca ttatagaagg gacaatacat gctcttccta ttgcttttat tcttccaact
    34321 ctggataaac acatcattat aactaatggt aatgtagcac ccaaccctcc taaagttatc
    34381 cagcctgttt gaataacttc gtaaacatat atattagttg ctactcctcc tgatgctact
    34441 gctgctgcat tagctgcaat tgcaccaagt tgaattgaat aagttatagg agatagtacc
    34501 cacccactta ttcctaaaga atatataaat actactaaga agtttaagag tacaaatcca
    34561 ggtaatgtct gtgctatatc tgatactggt ttaaatactc taactattat ttcaaacatg
    34621 tcaaagttga gtccataaat taatccccag cctacaaaca ttatcactgt tataggtaac
    34681 atattatcaa accacttgct tacaaaatcc ggaagtgctg aatcttctcc gaaaaatgaa
    34741 aaagaaccaa ataaagacat tattaatcca gagaataatc ctgcaactag cgatacaagc
    34801 attccttctc ctccaaacct gttgaagtta aatatagctc cttcattcgt aatctctgga
    34861 cgaatcatca ttaacattaa tccagcacct gcaagaccag ctactacact catactttca
    34921 aatttcttat tcttcattgt ttccataggc aataaaaatg ctataaataa tcctaaaagt
    34981 ccaaatgtat attgatttat tggacttaaa tcaggtaaaa agcttatgta attcttcaag
    35041 acagaaacta tagttactaa tgagcctaca aataccattg gcaaaacttt cattatagtt
    35101 gattgaactg attgtaccca tatattctta gtcatattat ttacaacagg agtaaatttt
    35161 tcacttaaaa aatctataaa tttattcata aacactctcc ccataaatat tttatttgtt
    35221 tgatattagt tctagtgctt cttccaaagc ctttgcacca tctagtcttc catatgcagt
    35281 tttagatata catgctactg gaacgttata ttcattagcc ttttgttgaa tttcttcctt
    35341 catataatct aaatgtggtc ctagtaataa acaatctatt tctgataaat acttatctat
    35401 ctctgactca cttctcgctt ttatatctgc ttctatacct tttttctttg cactctttct
    35461 catactagtt gccataaaac ctgtacttgc tcctgaacca cacgccaaaa gcactcttat
    35521 atttttcata ataatacctc caatattttt atccattaat ttatttctta atgaactttt
    35581 tattttatta tgtttatatt ttacttccca aataagttca tttcacataa atatatttcc
    35641 taataatagg aaatcattta ctcttaatta gacctattaa tatagtataa tgtatcttat
    35701 aatacgtaca ttcaattata taattatcat atcatacaga ttttatttta aaactatgcg
    35761 agggaatcta atgaaaacat ctaaaaaaga gctattttta aatttcataa aaacgcaaca
    35821 tgattggata gattcatcca cattagctaa ttaccttaat gtatcaacac gttcgattag
    35881 aaaatatgta aacgagatta attctaatgg tgcatttata ttatcttcta aaaagggcta
    35941 taaagtaaat ctcaatacta attgtcaaac taagattgat agttcagaga atatatcacc
    36001 tgataacaga ttaaatttaa ttttaaaaga acttatagtt aatagtaatg gaattaatat
    36061 atttgattta agtgaagaat tatttgttag cccagctact attgaagggg atatagtcaa
    36121 agctaataaa tttataggaa gttataattt aaagataaag caatcgaaat ttttattgaa
    36181 actagttgga aatgagtctg caaagcgcaa gttaatgagc tctataatat ttaaagaaac
    36241 gggaagtgat tttttaagct tatttgatgt acaaaaaata tatcaagagt ataatttgac
    36301 taaactaaaa gaaaatataa tatatatatt aaaaaaatac aatttattta taaatgagta
    36361 tgctataaac aacatacttc ttcatttaat gataactata gacagaataa aaaagaataa
    36421 ttacatagac tctgttgaag tagtaaacta catagacaat aacgtagata taaatattgc
    36481 aaaagacata tcaaattttt tagaatctga atacaatata actttaacta gtgcggaatt
    36541 atactattta gtatttcagt taacaaacaa aactacagtc ttaaactaca atcaaatgga
    36601 tactaaatca ttgtcaaatt atatagatga acactttgtt aaattaacta aaaaaataat
    36661 taaaaatgta tatgacttat atcttataga tttatctgat gaggaatttg ttgtaaaatt
    36721 tactcttcat gtaaaaaatt taatcagtag agccaaaaat aatcaagttt taagaaatca
    36781 aatacctcaa aagttaaaag attcctaccc tttgatatat gatatatctg tttatatttg
    36841 caatcagatt caaactttag aaaatgtaga tatagacgaa gatgaaatat cttatatatc
    36901 tcttcatgta ggttcattct ttgatagaca aaaattatta gaagataaag ttctatgtgc
    36961 attaattact ccaaattact atgatttaca attcaaaata gtaagagacc ttgagaagag
    37021 atttaatgaa tccatagaaa ttattcagat tttttcagat actcataatc ttgattttga
    37081 caataaggta gacatggtta ttactacttt accaattaac gatagatgcc ctataccttt
    37141 tgtttatgta aatccttacc taaatagaaa ggattatgat aatattcaaa gtaaatttat
    37201 tcagattaaa gatagaaaaa atatacttac tgtacaaaat catttagaaa tgtactttag
    37261 tgaatctttg tttatgaaaa atatatattt agatagtgct aaagattata taagatttat
    37321 gggaaatatt ctgtacgaaa ataaatatgt caaacccaat tatatagatg atgttcttat
    37381 aagagaaaaa atgtcttcaa ctgcatttaa taacaatgta gcaattcctc atagcatgaa
    37441 aatggatgct ttaaaaaccg gagtatgttt aattgttaac gataaaccag ttaaatgggg
    37501 tgaggaaaaa gttcaaatta tagctatgat acctataaat gaaaaagaaa aagaaaaatt
    37561 caattacata tttgaaagct ttattgaaat attatctgaa tggaataatg ttaaagaact
    37621 tactaaggca gataactata gtagttttat gaatagaata gcttatctta ttcaaaatat
    37681 ctaaatccat taatttattt ccaatatatg tttcttaagt tattaacata aaatagataa
    37741 gctgtcacac taaaaagtct aaattaatat gtgacagctt tttacctaat ataccttgtt
    37801 ttaatactac atattttttg actgttgtat actagttata agattgaata tttgtgttgt
    37861 tgtagctgtc atattctcac tagcagttgc tttatccatt gcttcttcta ttgtcatagc
    37921 tctatttact atagaaaaat aagcatctat accctcttca ttacatttaa ctgcatcttc
    37981 tgttgtggct ccagccaaac ctattacttt taccccatat ttttttgcca gttttgcaac
    38041 tcctattgga gccttgccca tagcagtttg attgtccaat ctaccttcac cagttatgac
    38101 aaaatctgca tcttttaact cttcctctaa tttaatttct tctaatatta tttttattcc
    38161 agattctaat tttgaatcta aaaatgctaa aaaagcaaaa cctaatcctc ctgctgctcc
    38221 tgctccttct acattagcta catctttact taagtaattt ttaactactt tggaaaaatt
    38281 tctaagccca ttatctaact tctcaattat ttctgatgtt gcaccttttt gagacccgta
    38341 tatgtatgca gctccatttt tcccaaacag cggattattt acatcacagg ctattttaaa
    38401 cttacattca tctaattcct ttaatctatt ttctattttt atatgtctta tttcatttaa
    38461 aacttttcca cctaatccta ctaacttgtt atttttatca taaaactcaa accctaaggc
    38521 ttgaagcata cctatcccag catcattagt agcacttcca cctatcccaa ctataaaatt
    38581 tctatagcct ttatttattg cttcctttat tatttcccca acaccataag ttgtagtgta
    38641 taaaggattt ctaagttcag tcggaaccaa tgttaatcct gatgcttgag ctatttctat
    38701 tattgctgta cttgtatttt ttaataatcc atatgttgca tccacttttt tagctattgg
    38761 tccagtaact tctatagtct cttttttacc attcatccct tgaactaaag catctactgt
    38821 cccttcacca ccatcagcaa gtggcaatat ctttacttgc gcatcttctt taaccttcaa
    38881 tatccccttt tttattgcat ttcctgcctc tattgaagat aagcttcctt tcaaagaatc
    38941 tatagaaatt aatattttca tacttatcta ctccttttta ttactcctta ttttaaacat
    39001 ataattttat aagcttaatt tatcttttat tttatactct acatctctct ttgtatacaa
    39061 cttataccat taatattctt ttatcttata aaaagggagt gtctcaaaat aaatttctta
    39121 gttcatgaga cactcttttg tataaaatca aatatatgtt tattatttca acaatgataa
    39181 ggaggattat ctctatttta agataattcc tttttagcac tatctaatca tttttagcac
    39241 tatttaacca gtatagtttt aacttggttc attaagcact ctacatttac agagttatta
    39301 tctattgata tagattctaa ttctttttca tttaggttaa tccatttagc tgttttaata
    39361 tttttgttaa atactatgtt agctgatttt gtttcttctt tagaattata aaatctaact
    39421 actaatgcct cttctttttc agcctttttt acaacactta acacaaggtc cttattagtt
    39481 tccttaagta aactatatga ataatctact tctatttctg attgattcaa tttcatagca
    39541 ttatatggca ttttattata agtttgtatt tttgttaaat actctttagc catatttgca
    39601 acatttgctt ctagtgtaga tttttcatga gtaactattg ctaagtctat ttttatatct
    39661 cctatcattt gagaatctgg agtaggcaac tttattcctg atggacgacc tgggcgtctt
    39721 gccatttctt ctttacctag gaatcctaca cttctaaata atgttatagc tattgtgtca
    39781 aatttttccc ctactatttc aaactctctt gtactgtttg taagaacagc tactccatgc
    39841 tctttgtcag acaatccaac gaatgttagc attggatata tagaatctgg tctttcactc
    39901 cagtcttcct gttgccaaac ttccatagca tcatcataca cacttctctt tatatgtcca
    39961 aactgattat cagacacaga aaactttgaa gctatatttg ttggtatata agttctaacc
    40021 ctacaatctc ttgcttggtt atttatgttg aatactacat ctattatagc tttatcattt
    40081 ggaacattta taactatatc aaagtcaata aatgaatctg ctctattatt ttttctagct
    40141 tgtatatctt ttggtacttt taatctataa tttatcttta tctcattatt aaatctattt
    40201 ttctttatag tggaatttgc tactatatta tcgttaaata ttaatttctc atttggaagt
    40261 ggtgaaaaat catactcatc tccttcatct cctccatttt ccatcaataa tacattttca
    40321 aaagttttat ttaatttttt atcaaatatc tttaatgtcc cgttttcatt aacttgaata
    40381 gtataaaagt cattatctac catgtcacat acttcataag ctttttctaa catatgttca
    40441 acttctttta tcatatacgc cttatacccc attgcaggta ttttatcttt aaagtttatt
    40501 gtatatacca taaatgaatc atagtttcca taatgaacaa tttgacggtc tattaatcct
    40561 gcatctatta cttctttatg taccacttca aaatccaact tattattatc tttatcaaat
    40621 atttcaaatg ctttcatttt agttataact tgggcgctca ctatttcatt cctatcgtaa
    40681 ggcattaagt taaatgctat taacttatct aaagccattt cacaactcat tgcatcaact
    40741 attcttcttt tgtaaaatgt tattaattgg tctacttttt cctcagctaa gaaaaatcta
    40801 ttcattattt cctggtgaac tttatctgaa caacaacatc caatgctgtc atgagcatga
    40861 tttttcatta tttctttcca aattaactct attaatccat gatgatattc aaatcctaga
    40921 gaatatgcaa tagaagctag tggctccaat atgttagtta tctttgattc tattctagca
    40981 tttgctgatt ttatatccat tcttgttgag aatatacttc tatgaaccct catatatttc
    41041 ccatctaaaa attccccttt tattgtatct atatcctcat ttttttctag ctctttaaat
    41101 atgttttcat atctacttaa gaaaaatttt ctgtctggat aacattcttt taatttatat
    41161 ataacttcaa atatattctt ttgaattggc atttggtcat gtccatttgg aagtattata
    41221 tggtcagtag ttgcaccctt atcaagaacc ggtaaatatt tatccattct tgttcttagc
    41281 tcatcttcat tcattggtag atattttcct attgcataac ctaatggaag tatttgaacc
    41341 aaaacagaag acccatcatc actcttccaa ttaaactctg ttttattagt tccttttctt
    41401 tcagaacatc ctctccaaaa cattgaatat tttatatcaa acccatttag tatttgtggc
    41461 atttgagcac tttgaccaaa tgaatctggt aaatatccta ttttcatata ttctccaaat
    41521 tcatcacaat cttttattcc atatagtaaa tttctaagta tggattctcc accaactacc
    41581 atttcatcag tttgagtata ccaaggacct attattagcc ttccttcttg aactaatttt
    41641 tttattctct ccttacattc aggcttaact gctaaataat cttctaatat agcagtttga
    41701 ccatccatca cataatatgg atagttatga ttattttcta acatatccat tatttcttcc
    41761 atattattta caagtaatat tctagattcc tcagttgaga agtaccattc tctatcccaa
    41821 tgcatatgag gaactatgtg tacatttttt ttcattgctt atcctccaaa acttatctga
    41881 taatattttc tgtctaatta aaaatccaat aaaaatacta ctgagtttac aaaatttttt
    41941 aatatttatt ttatcactat aattaaacct ttgatttaaa tatctaataa cgtatctttt
    42001 aatgtatctt tctttgattt ttttgtttcc tagttattat taataatatt gctgatatta
    42061 tagctccaag tactgccgca aagaaccata ttgatgctat aataaatcct gacatacttc
    42121 cctctaaaag cgccaatgag aatatccccg ctccaggcac ttgaagacct atattgaaga
    42181 atgctactat agacccagtt atggctgaac cagctaccaa tgatggtata acacggattg
    42241 ggtcctctat cataaatggt attgcacctt cagttattcc agccaatcct aatatccaag
    42301 tttgctttcc tatttccttt tctgattctg aaaataaatc tctgcctaaa acagtagcta
    42361 ttgtaactcc aaaagctgaa accatcttaa ctgatgcaaa tattgcataa ggtataaaat
    42421 ttccacttgc tattgctcct attgcaaatg tataggctgc tttatttatt ggtccaccta
    42481 agtcaaatga aaccatagct cctattattg cacctagtag tattgcattt actccagtca
    42541 tcccatttaa ccaatttata agaccattgt taagtgctgc tacaggcttt cctactacaa
    42601 ataacatcaa taaacctact accaaagaac caactactgg atatacccaa aaacttacga
    42661 atccagctaa tgtgcctttg gctggtatat tcttctttaa aaattttact atataaccag
    42721 caagtaaacc tcctaacata cctccaagaa atccactacc tattaaatca gctgctagac
    42781 ctgctgcaaa tcctggtcca agacctggtt tttcagctag tgagtaagac atatatgctg
    42841 ataatactgg aaccatcaat gtacctaaca tacctccaga aagctttctt aattgccata
    42901 accaagaacc ttcttgattg tatagttctt gtagaccaaa tgcttgagat gctaatactg
    42961 caaatgcaag tatcatacct cctgccacaa taagtggtat tatatgagat actcctgtaa
    43021 gtattgctga ttttacatct tttttccatg atgatttttc acaatatgat atatcagatg
    43081 atttttctat ataatcacct ttaccttgtt tttgtgctac ttctaaagct tcgtatatta
    43141 tttcttttgc tctttttagt ggagctgcta ctgacgtttt tatgtttggc aaatgttcaa
    43201 atctttctgt atttttaggt gctacatctg ttgcatatat tattgcatct gcccttttta
    43261 ttatatctgg cgtatgaggg tccaccatac cattagctcc ttgcttttct acatacacat
    43321 ccacacctat ttctttacca gctttaatta atgcttctgc tgacatatat gtatgtgcta
    43381 taccggcagg gcatgctgtt attgctaata taattttttt tgattcattt tgaatcctaa
    43441 tctcttcttt tatttgttct ttcttttctt ttatatctaa gttattaaat aactctttct
    43501 tagtttttga atttaacaac atattcatat aatcttcatt tgacagtcta gtaactaact
    43561 cagaaagtat ttgtatgtgt gtatttccac cttcactttc tggtactgct attaaaaata
    43621 ttagctctac tttattattt gggtctacgc tttcccaatt ttctattggt gtctctaagg
    43681 tcatagctgc aaatgcagct tctttaactg acttagattt tccatgagga attgcaagcc
    43741 ctctttcaaa acctgttgga gataaagttt ctctgtacat tacagcttct aaatattcct
    43801 cataagatgt taacttgcct tcatcatata gctttcttgc taagaacttt attgcgtctt
    43861 cctttgtttt tattttttgt tttaaaaaaa caaggttttc atttgtgatt ttcttaaatt
    43921 ccaaaattac gccctcctta aatcatttaa tgctatgaat atagcataaa ataaattatg
    43981 aaaatgtttt tttgaaatta tacacacaat ttcttcttaa aaaataaaga tttgtgtatt
    44041 tatacacaaa tctctatctt aaccaatatt gctctattat tgctctcata atcatcataa
    44101 ttggaacctt atctgatata ttgtacccat ttacttgttt aattgttgaa tagcaatata
    44161 aacttatatc tgcaatttgt tgcaattgat tttcacatat atgtgttaaa gctactacct
    44221 tacaaccctt attaactgct gtctttgctg cttctataac ttctttcgtt tctccactta
    44281 aactaagtgc aaaaaacata tcttgttcac ctaattttcc tatatcatga agtacttcat
    44341 gtctttgact atagtaagtt atattatcat gcccacctct aatttctttt actaatatct
    44401 cacataaagg aatgttttga cctattccat aaactataat actcctagat ttttgaatta
    44461 tatctgctac tttatttatt ttttcataat ctattagctc taatgtcttt tttatatctg
    44521 attcaaaacc attttttggc tctttatcct cattttttaa ctcttctttt aaattatttt
    44581 ttagttgaga gaaaccatca tactccattt ttttacatag cctaactatg gtatttggga
    44641 cagtaaaaaa tttatctgct aaagattgta ttgataattt tactatttct tctttgtttt
    44701 ttctcatata ttcaattatc atgtcttctg tatctgtaaa tttatactca tatttttttg
    44761 ctctttcata aaattccata gtttctcctc catctatttt attattcata agtaaaattc
    44821 aaaaatatta gctaaaattt tcgttaatat aattataatt taatattttt aatttattaa
    44881 tgcatactac tctttttatt atacataaaa aatgtgtact tcctatattg atagagatga
    44941 ttcaagtttt tattttgata catctctatc aatatttttt tagaaaatac acattttttt
    45001 caaatactta tttttaatta aaactttagg taatctattc tttatatata attattagac
    45061 ttgaaaatat ctttaaaatc aaccaattca atattatttc tttttaacca cattttaact
    45121 tccttatcac atagcattgc atgttcatat actctctctt gaataagaga agatgatttt
    45181 ataagactat aatctataaa tcctggatga gtaaccatca atgttatatc tttatctaaa
    45241 tttatatatt tttcttcaaa taatttaaca aaagatttat ttaacttgta aaaatcattc
    45301 tgaggatatt tacttggcat gctaatacat gaatccaaat aatagggaca acttggtata
    45361 ccgtattctt ttgcagcatc acacattgct gatattgata catcttcttc tataccatgt
    45421 atatcaatat actcaggcaa tttactcata tacaacttgt aagtttcaat ttgagcacaa
    45481 acttcttcat atacttcttc ataattaaaa acctctttac ctgtcagtag ttgcgttctt
    45541 cttattttgc tagaaacaaa ttttccacct tcatctaaca aattctttat cttaatatgt
    45601 tctttgcaac aaggttctcc tattactaaa ttaacatgta aaccaaaaca tacatcatca
    45661 ttttttacca tttctatagc ttgtcttgaa aaaggcatat tcaccatgat tccagcactt
    45721 gtaacaatac cgttcttata agaagatatt atccctagtg taacaccttc tgaatatcct
    45781 atatcatctg ccctaactac taatttcttc attttatgca tctgcctgct ttctcaactc
    45841 atcaagttgc atttccatct catcctttac tttaacaaca tccgttccta tgatgatttg
    45901 aactgatgta ttactcaatt taattacccc tttggctcct gtttttttaa tattatcatc
    45961 attcaaaata gtggcatcct tcacttctaa acgtaatctc gtcatacaat tattaagagt
    46021 cactatattt tcataaccac cacaattttt aattatctgt ttagccatat atgaaaaatt
    46081 accatgagaa agttttaaat tcttttcttt ttcactaact ttatcaccta tctctatctc
    46141 aacttcacgt cctggtgttt gcacattatc ttttattatt atatatttaa atgttacata
    46201 atataataca aagaatacaa ctcctacagg tataactaac cacgctttat ctccataact
    46261 aaaacttaag acatagtcaa ttatacttgc tccattaaat gaacccaagc gagcacccaa
    46321 taaatatagt acaactccac ctagaccaga ataaaaagaa tgaattatat ataactttgg
    46381 agatgcaaat aaaaacgaaa attctattgg ttcagttact gttgccataa aagaagtcaa
    46441 tgctccagcg gtcattgcac cttttacttc ttgcttcttt ttatcttgtg ctgttttata
    46501 tatagcataa gaaatagcag gtattgaaaa catcataatt atgtaaaatc ctgtccagaa
    46561 gaatcctgca tttgggtctc ctgccataaa tctaggaatt tctcctctta taacttctcc
    46621 tgttgatgtt gtatattcac ccatttcaaa taatatgtaa gcatttaaaa cttgatgtaa
    46681 cccagttggt attagtgcac ggttacagaa taaaaacaag aatattccta ttgcaccagc
    46741 tcctcccaac caaaaaccaa attgattcat tgcagcttgt ggatatatcc ataataaact
    46801 aaatatatat gataaaatta aagcaaccac tggtgatagt gtaattacac atttttctcc
    46861 tgcaaagaag cttaaaaatg ctggaacttt aactttatat gttttattgt aagtccatgc
    46921 tatacaagct ccaacaatta tcccaccaaa tacacctgca tttaatgtat cattcaataa
    46981 ctctaaattt gacttaaata tcatatatgc aactacggct gcaaccatta cacttgtctt
    47041 gtctttagac tttgagtagg cactagctgc tcctaataaa aataagtagt ccacatttga
    47101 aaatactata ttagatatat tagatatagc tggcacattg agcatatttg gaccaaataa
    47161 taatcctaat atacctgctg ctggcattac agctattggc accagcatag tctttcctaa
    47221 aagtgacagt tgttgcatca ttttgtttaa gaatctcttc atatccaatc ccctttctat
    47281 ttcggtttaa ttttttgtga aaacgattta ttcacatttt atattttaaa tattatattt
    47341 gtttaaacaa attgtcaata ttttttattc attttatttt tatcatttag tttaacatat
    47401 aaatcctttt aagtgtattg ctatatctag tctatttttt taattcattt tttttatttt
    47461 aaaaatatgt ttaaccatgt atttgaaaca acccacaaaa taattctatt ttgtcctttt
    47521 tatggttgat atgattctat tttcactata catgtctaaa cacatttgat ataatttgtt
    47581 catatcagtt caataatatt actaaagacc tttaaggagg gataggggta tatggctaaa
    47641 aataaatttt cagagatata tgaagtattg aaagaggaaa tacttgatgg taaatataca
    47701 agtaatatga tgctgcctac tgaacttcaa cttattgaaa ggttttcatg tagcagaaac
    47761 actgtacgta gagcaatttc tcaattaaac acagaaggat atgttcaaag tataaaaggc
    47821 aagggtgttg tagtgttaga aaatagttgt tctaatgatt tttttctaaa tatgcacaat
    47881 ttcaaaggtg tagaatcgat tgtagaagat aaaaaggtta atactgctac tagtgttctc
    47941 cacttcagca aaatcttaat tgataataag ttatctaaaa agacaggttt taaagttggt
    48001 agtgaagtat attaccttca cagactaaga tatattgata acatacctaa aattctcgac
    48061 attaactatt ttctatgtag tatagttaaa gaccttgatg tttctatagc acaaggctct
    48121 atttataaat atatagaaga gtgtctaggt acaaaaattg tttcatcaag aaagatattt
    48181 aaaattgaaa aagctacaga acttgagtta aaaacgctac ctctaaatga ttataattgt
    48241 gttggtgtta ttaaaaatag tgtatatact gatgatggaa agctttttga atatactgaa
    48301 tcaaagcata cacctgaaac atttgtattc atggatgtta ctcaaagata ttaaaaaaat
    48361 tatgtttaat taaacataat ttttttacgt ttagacactt tatcccatac taacctcact
    48421 attctatata caattatatg tttatacaaa taattattta ttgtatattt tagctttaat
    48481 attagtttaa cgcttgacaa tttgtttaaa catattataa ttaacttata aattacagga
    48541 ggtatcaagt atgaaaaatt ggtggaaaaa agcaactgtc tatcaaatat atccaaaaag
    48601 tttcaaagat agcaacaatg atggtatagg tgatataaat ggtattatag aaaaattaga
    48661 ttatctgtat tctttaggtg ttgatttatt atggttgact cctatgtacg tttctcctca
    48721 aagagataat ggatatgata tagaagatta ttataatata gacccaaaat atgggacaat
    48781 gagtgacttt gaaaaactct taaaagaagc tcataaaaga gacataaaaa taatgatgga
    48841 tatggtccta aaccatacat ctactgaaca taaatggttt aaagaatcta aaaaaagcaa
    48901 agacaatcca tatcgtgatt attatttctg gaaagatgct aaacctgatg gttctgttcc
    48961 taataactgg atatccagat ttagtggaac tgcttggaaa tatgatgaaa ccactaacca
    49021 atattattta catttatttg aagaaactca agctgattta aattgggaaa atgaaaaggt
    49081 tcgtgaagaa tgttacaaaa tactagaatt ttgggctgat aaaggtattg atggttttcg
    49141 tttagatgta gtcaacctac tctccaaaac acctggatta cctgatgacc ctataacagg
    49201 accaaaagga gatggaagaa ctcactacgc tgatggtcct cgtatacacg aatatttaca
    49261 taatatgaat caaaaagttt tcaaacctaa aaatatagtt actgtaggtg aaatgtcatc
    49321 tactacacct gaagagtgta tcaactatac tagagaaaat cgagaagaac tatctatggt
    49381 ttttagcttc catcatatga aaacagatta taaaggaggc gcaaaatgga ctaatgaaat
    49441 gttctctctg gataaattaa aaaaagcaca atctgacttt caatataaaa tgtatgaagg
    49501 aaaaggatgg aatgctctat tttactctaa tcacgaccaa cctagagctt tatctagatt
    49561 tggagatgat agattttttc gtcaagaaag tgctaagatg ttagccataa cattatttgg
    49621 tctacagggt actacataca tatatcaagg tgaagaaata ggtatgacaa atgcctactt
    49681 tactaaaata gatgaatatg atgatgctga aagtaagaat gcatactatc atatgattaa
    49741 atctggtatt gatgaaaagg aggcattgct tatacttcaa caaaaatcca gagataatgc
    49801 ccgtactcct atgcaatggg ataatactat ttataagggg ttttctaatc ataaaccgtg
    49861 gttaaaagtt aataatgaca atattagtgt agaaaatgag cttaatgatt ctcgttcagt
    49921 attttatact tatcaaagat taatcaaata tcgtaaacaa tatgatattt ttacagaagg
    49981 tacttataga ttgttagatg aaaatcataa aaatctattt gtttatgaaa gagagtataa
    50041 aaaccaaaat cttcttgtta taagtaattt tactcatgat aatgtagtat ataaattacc
    50101 tgaaacttat ttgaataaat taaactacac aatacttgaa accaattaca ctagagatat
    50161 aattgaaaat aaaatggaaa taaaacctta cgaaagtata atgatatatt ataaataaag
    50221 ttatttatgt aaaaatcggt ataacaccct ggtgttatac caattttact aaattcaaag
    50281 taatatttat agaatatcta tagattacaa taattatttg acttctacat cattatattt
    50341 ctttgaatat actttagtca tatagaaata tataggaact acaattatca tcccacctaa
    50401 tccccaaact atcttcatag gttcatcaat acctgctttt atcagtaata atatacttat
    50461 aataactgca aatattggta taattgctcc tccaggtatt ctaaaattta catctttacc
    50521 agcatacttc tttctcaata ttagtacagc taaacatgta ggaatatatt gaataaatct
    50581 agatacaaca cttatttgag ataatgttgt gaatgaaccc gaccatgcta ttagtaaagt
    50641 tcctatgaca gatactataa ttgctatata aggagctcca tttttattag tttttcttat
    50701 agacttaggc attaatcctt gttcaaccaa agcagcagca gaccttggtg taaatatgga
    50761 tgatgcaata tttatacctc caacagatac tatagttcct attgtaatta tatacccacc
    50821 tataggacct aacatcttaa tggcagcatc tgcaacagga gtagctgacc ctgctaagcc
    50881 attacccaac acccctatac ttattcccag tataagcata tatattactg atactacaaa
    50941 cattaccatt accaatgctt taggtacatt tttcttaggg ttctccatat cttttgctgc
    51001 aacagctaaa gattcaaatc ctgtaaaagc ataaaataaa gttatagata ctgctacaaa
    51061 agctgatgac gcactttgac ctttttgtat tattacaaat ggggtaaaat tagaaccctt
    51121 tataaagaat aatcctacag ctataaataa aactattggt aataattttc ctatagtcat
    51181 gatattattt aagtgcttag attgtttcat ccccataaaa tttataatcc caagtcctac
    51241 aactaatata ccaattatta tatttttagt aagtggttct gctgcttgtg gccatacaga
    51301 tgatagtgtt acagcaaaga aatttgccat agtagcccaa gcaatcatac taactatcca
    51361 cttcataaat ccaacttcaa atccaacaaa atctccaaat gcctcttttg cataaagata
    51421 gggccctcca tcagtatcaa accaactacc tgcttcagca aaacataaag caatagaaac
    51481 agctaaaagc atacaaaaaa ctaatactaa tatacttgct ggacctatat ctgtataagc
    51541 atcaccaggt aacccgaata tacctgaccc tattattgca ttgattccta atagtacaat
    51601 actccaaaaa cctaacttaa tgcctttttc cattgttatt ccccccaaag ccaacttaat
    51661 atatttgtat tttttattta gatgcttctt taactattgc cataaatatt tttttcatat
    51721 tatcataatc cctagtcatc atttctggat gccattgtat ccctattaca aactcacttc
    51781 cttccttttc tatagcttca attaaaccgt ctttagatgt agctgaaaca atatatcccg
    51841 gtgctacttt gttgacaact aagtgatgaa aactattaac taaaacttct ttttctccta
    51901 atatttcata taattttgtc ccctccttta tctgtactgt atgtgtaggt acattagata
    51961 gatgttgctg attgtgttta atataagcac cttcaattaa agataaatct tgatacaaac
    52021 tacctccttc agttacattt ataatttgtt ctcctctaca tatacctaaa actggttttt
    52081 tcatatctaa agcatgtttt aataatttca tatcaaaact atctctcttt ggtgatattg
    52141 cccccaactt attatgaggt tcttctttcc atatgagtgg atttacatct tgtcccccag
    52201 atagtataag cgcatctata ttagatacct gctcctttat aatctcatca tcatatacaa
    52261 tcggtacaat atatggtata gctttacaca taactactga ttgtatataa tcattattta
    52321 cataagccct ttcatagcca ggaaacattc ctccttcatc aattagtaaa ttacctgata
    52381 ttcctattat tggatatttc tttttagcca atttcttcac cccttaactt atttgtgaac
    52441 aataaaaaat gctacttctc ttaaagagca agtagcatac caagatttta tttatttgaa
    52501 cattataatt tattttagaa atactttttt tgaatacgag taatataaat aactttattt
    52561 acttatattt tattttaatc ctgtttagtt tgactttttt aaattgtttt aagtacaact
    52621 aataggtaaa ataggcattt agattttcct ttttatcaac ctattaaata ctgtttaata
    52681 tattttttcc ccttctattt aattcacttc cctttctacc agattcacat attatcaaat
    52741 ccagctcttt taacatatta agtattcccc ttacctcacc ttctgttata ttgtagccta
    52801 attcatttat tgaattaaca ataccatttc tacctatatt tttattaaga ttattggcat
    52861 tttttaaaca ctccattact aactttactt tctctataga tgttctatcc tttaatatac
    52921 ttatttcttt actaaaatct tcagttatat ttaataagtt atgaggtaaa tcatttatta
    52981 aaataacatc ctcagaactc ataatgttaa tatacatagc agtatttttt aattctctta
    53041 tattacctgg ccattcatat gcattaataa tgtcttgaac atcttgacta attgctctct
    53101 tccttttcat aaaatgcttt aacataactt ctatatcttc ttttcgctct cttaaaggtg
    53161 gtatatttat gggcaataca tttatcctat agtataaatc tgctctaaat ctatctcctt
    53221 ttatcatttc taataaattt ttatttgtag ccgcaattac tctaacatct atatctatta
    53281 cattttctcc tccaaccctc attacttgat tctcttgtaa tactctaagt aatttgcttt
    53341 gtaagtatat aggcatgtct cctatttcat ccaaaaatat agttccattg ttagcctgtt
    53401 caaataatcc ttttttacct ccttttaaag ctcctgtaaa agcaccttct tcatatccaa
    53461 aaagttcact ttcaagtaaa ttttctggca tagctgcaca gtttatcgct ataaatggct
    53521 gactatgtct tggtgatgca ttatgaatag actgagccat gagttctttt cccgttccac
    53581 tttctcccgt tataagaatt gtataatcag attcagctat tttcatacct aatttcttag
    53641 ttctttccat cttcgttgaa actgttttta tatcatcaaa agtatatcta gcaacttgtc
    53701 ccttttctct aagcttcttt gataggtttt gctccaattt tcttatgtaa gttatttctt
    53761 gaatacaaaa ataatatcca gtaacccttc caaaactctc tatattatac ttatttacgt
    53821 ttaagtactt attattaaat tttataactt catcatgtgc cttactcaaa ctaaaaatct
    53881 ttttaatatt ctcattctct aattcatcta tatttttccc tataatatta ctttgaatat
    53941 ctagtatatc ccctaaacta ttattgcaaa taattatgtt tcccttatct gataccattg
    54001 ccatacctaa gtttgataaa tttattatag aatttaattc atctgctttt atagtaagtt
    54061 ctttatattt agtatttatt cctgaatata aactaattat ttcatctgta tacttaatta
    54121 gcctttcagt aatttcttta tcatccagtt tgagttttgc tattatttga ataaacgttg
    54181 aactatcaat atacctatgg cctaaatcaa taacttcttc tatatatttt ggaactaaac
    54241 ttgcctctcc tggcgttata gctatcttaa tatttctata ttcttcattg ggattgtatg
    54301 gtataaaatt cagatgattt attcctatat tgtataaatt agatattgtt tccaatacag
    54361 tatgcttatt atcgtttact actaatacat ctattccttc tggcaatgaa aataacttat
    54421 atatatcctt ttgctttatg ctcctattta tagttattat ctttgagaca tcttctacat
    54481 atttttttat ttttaatact ctatcatcta tcattaccaa tattatgtca tcttttatta
    54541 attccttctc tgttatttta tttaaataat aattttttat cattacttta tctttaaata
    54601 tcatttctag atttttattt aagaaacatt ctaatttaga caacccatca gttactactg
    54661 ctattgtttt catttgatta ctccttttaa aatatactct actcttttat aatatacatc
    54721 tgattttcac tttaacagca caaaaaattg tacatttagt atactaacat attcctttat
    54781 tagttttatg tccctaaata tcatagttgc aatatctatc atatttctta aacttctata
    54841 aagcaaaaat tgtgccaaat taataatttt cttaatttta ttctaaagtt cctcaatagt
    54901 atttacagac ttagcactta tagcttataa gtctttatat tattaatcta tttttatagg
    54961 ttaattgtac aaatcatata tcacttttac ccattaaatg cattataaaa aagatggaat
    55021 aacgattcgt cactccacct tttttgtaat aaaaaattgt atatataaac actatttact
    55081 actcttctaa gtacaaacat tatctacata ctataacctt tcaccattag attctattac
    55141 ttgtttatac cagtcaaaac tctttttctt aatcctagac aagtctccac ttccatcatc
    55201 atacttatcc acgtatataa acccatatct cttggccatc tcaccagtag atgcacttac
    55261 taaatctata catccccacg gagtatatcc aaataaatca acaccatctt ctacagcttc
    55321 cttcatttgc tctatatgtg cttttaaata ctctatacga tagtcatcat ttatcactcc
    55381 attagattct tttttatcat aagctcctaa accattttca actaccatca taggtattct
    55441 atatctatca taaatttcat ttagtgcata tctaagccct tcagggtcta tttgccatcc
    55501 ccattcacta gacttaagat atggattttt cactccacct aatatgttgc cacttgtatt
    55561 atcttcttta gaatcactac ttacacatgt agacatataa taactaaatg tataaaaatc
    55621 tacacaacct tcttttaaaa tttctaaatc tcctttttcc atttttattt caatattatt
    55681 ttctccaaaa tatctattca tataagttgg atattcgcca cgcacttgta catctccaca
    55741 gaaataattc attactctac tatctctttg agttttaact gcatcatctg gattacaagt
    55801 ataaggatac attgttgcaa atatttgcat acatccaact tgataatttg aatctatttc
    55861 atgagctaac ttaacagcct tagcacttgc tacaaattga tgatgtaacc cttgaaaacg
    55921 aagttgaggt atatctactt ggtttataaa atctgtagtc ccttcattta atattccttg
    55981 tgataagtag cctcccatag gcattgtagc tgaatttatt tcattaaatg tcagccaata
    56041 ttttactttt cctttatatc ttttaaatat tgtttcacag taattcatat acaagtctat
    56101 tacatctctt gaaacccatc cattgtattt ctctgttatt gcaaatggta tttcatagtg
    56161 agatattgtt attaatggtt ctatattata ttttaaacat tcatctatca cattttcata
    56221 aaatttaagt cctgcttcat ttggttcttt ctccattcca gttggaaata ttctagtcca
    56281 tgctattgaa aatctaaata ccttaaatcc catttctgca aataaagcta tatcttcttt
    56341 gtatctgtga taaaaatcta ttgcttcatg acttggataa aatgttcctt tttctataac
    56401 tctcgttatt cttttactta ctttttgaga acctccagta cacatatctg aacaagaagg
    56461 acctttccca tctaaattcc atgctccttc acattgattt gctgctgttg ctccacccca
    56521 taaaaaatct tttctaagtg ccataattct acctccaata atttatttat agtaacttta
    56581 ttttaaaata aaaatacata tatataattc ttaattaata gaactctctt ttacgctaaa
    56641 acagttatca attcctgact attatttaca tgcttttgtg tattttctaa aatatccaca
    56701 taatcagaat aattagtaac aactactggt gtttctaagc aatatccttc ttttgaaata
    56761 ctttctatgt caaaagttat taatatctga ccttttttaa tcttatcccc ttgattaaca
    56821 aaagatttga aatatttacc ttccaactga atagtattta accctatatg tatcaatagt
    56881 tcacaaccat tatcagatat aattcctatt gcatgttttg ttggaaataa agtcattaca
    56941 gtcccatcaa atggtgccac tacttttcct tctttaggtg ttattgctac accttttccc
    57001 aatatacctg ttgaaaacgc tgcatcttgt atctgctcca aagcctttac ttcacctttt
    57061 attgggctat atactacttc tcttttgttt ttttctataa cgccttgccc attatcatct
    57121 ttagaaattt ctactatagc atcatctttc caaaaaaata atgttaaaac aaatcctact
    57181 acaatagcta ctattattgc tattatagtt gcataaacac ctttcatatc tccagttgtt
    57241 ggatttatat aattaggtat accaaatatt ccaagtccac ccattacata actttttaca
    57301 ttcattatcc ccattacagc tcctgccaca ccaccaccta cacagctata tatgaatggt
    57361 gtttttcttg gtaaagttat tccatatatt gcaggctctg ttacaccaca tatccctgaa
    57421 ataactgcag gtatacacag ctcttttatc ttcttatctt ttaatttaaa gtacattgct
    57481 gctactactg ctgtttgtgc aaaagatggt acaaatgctc ccactaatat tgtgtcaaac
    57541 cccatagtca taaggtttga catagctatt ggtactaatc cccaatgtag accaaatatt
    57601 acaagcactt gccacaataa accagttaat gcaccacata aaattggtga aaagttaaat
    57661 aaagctaaaa atccatttcc aactatatta gaagcatagg tagctatagg ccctataacc
    57721 ataaatccca atggtaaaga aactaataaa actgccattg gtacaaagaa attctttact
    57781 acatctggta ttattttagc aaacactttc tccaacttag ctgctaataa tactattaaa
    57841 attactggta ctactgttga agtgtagttc attgctatta ctggtaatcc taagaaagtt
    57901 atatatactg gtgattcaaa tattgttcca gtaaatagat tgtataaagg ttgacctgta
    57961 gatgctagag tatctaattg aatacctgaa tagcataaaa ctgcacctat aagcattcca
    58021 ataaatggtt ttaatttgaa tttcttagca gctgtatatc caagaattat tggcatatac
    58081 tggaacattg catctccaat tgcatttaac ataatatatg caccatcagt ttctccatac
    58141 aaacccaatg ctgtaaatac tgcattaaat ccttttatca taccagcagc acacagaact
    58201 cctaatattg gttgaaaaac tcctgatatt atgtctataa acttattaag taatcctttt
    58261 ggcgcatctg agtctgaatt atctattgta tctcctccta atccagccaa atcgcacaca
    58321 acttcataaa catctggaac atgattacca ataactactt ggtattgacc tgcacttttc
    58381 attacagtaa ctataccatc catttttttt agcacatcat catttgctat tgactcatct
    58441 tttaatttaa aacgtagcct cgttatacag tgagataaac tgctaatatt atcctttcct
    58501 cctacattcg caatgatttc ttttgatagt tgttcatact ttctcatttt ttctcctcca
    58561 ttttcttttt gaaatatgaa ggtttggcca acttaatgtc accacccaat atatataaac
    58621 ctaattatta ggatttatat ctgacttaat acttttactt accactcttt caacgtgaat
    58681 agttaagtat aatttttcct catctgttaa atcgtagttg tattttttat gtataaattc
    58741 atccaacttt tctatgaatt tataagcatt tttatattta acttttatta catttaataa
    58801 atcatcttca ttattttcat gtaaattatt actaacaatt cgttctgcaa aatactttaa
    58861 gtgagtaata aatctatgat aataaactga atcttcatca aatactattc tgtaatggta
    58921 tttaaccata tttgaaattt cttgtattat ttgtgtaatc tcatatatag tttttatact
    58981 ttgatccatt tgtgcattaa ctatatgcag tgctataaat ccagcttcat cttctgatag
    59041 tctaatttca aatttttttt ctatataatc caatgcctct aaccctattt taaattcact
    59101 cttataaaat ctttttatat cccaaagtaa tacatttttt acacttactc cttcacgagc
    59161 tctttctatt gcagtataca tatggtctgt taaagaaata taaatactat catttaatct
    59221 tttccctagt ttttctttag catataaaat tatttcatct gataattcca tatatcttat
    59281 aggaatatct gctattagtt ctttaaattt atcagatata tttgggtctg aaagtttgaa
    59341 tatcttatca attttatcct ttgatatatg ctctcctgta cgttttttat aagctaaacc
    59401 tctccccata actactattt ccttatgatt ttcatcagtt gtaataatta cattattatt
    59461 gagtattttt tcaataatca ttgtgatgcc ccctttatta gcattaagtt aaaataaatc
    59521 ttttttaatt atttagaata tttaaaatgt aatttattac ataaaaaaaa acctatttat
    59581 tacacattaa atagactccc atgagtcctg agtaataaat aggtttagct tgtatttaaa
    59641 caatcactat ccgtttgtat tttattttaa ttattattta ttatatgtta gcaaatttat
    59701 tttttagtgt caactttttc tcaatatttt aattttaaat aaattatata aattgaatct
    59761 tcaaagtact atttttatca ataaacaaaa taaaaaaggt attactttct ttaagtaata
    59821 cccatttatt tttaatttaa gtggtttttc ttaatctcat caagtagtcc atcttctaaa
    59881 taaatttcta atgcacatcc taccattgcc tttactgctt tgtgaagttt atcataagct
    59941 tcctcagaat ttgcataatt tagaaattct ttttcatgaa catataccat tggacttata
    60001 tctaaggcta tttctgtata catagtaggg caaacttgac ttacattacc tatatctgta
    60061 gaacctactg gaccatcttt accttctaat atatctgtta tacctgcctc aatcaaatta
    60121 ttctttgtta tcttttgaag tactttgtta tttattatgt tgtcaaaaga attttcaaag
    60181 tatctataag aaagcttagc tcctgtcatt aactctgcac cttttgcaca gtttataact
    60241 tttttagtta cttcatctaa ataacttctt tcagcagctc ttacgaaaaa cttacaagct
    60301 gctttttctg gaactatatt tggagcctct cctccatttg aaactatacc atgtattcta
    60361 acatctgatt ttacatgttg tcttagtgca tttatcccag caaaagtaag ttgtactgca
    60421 tctagtgcat tgactcccat atgagggtga ctagctgcat gtgctgatac cccttcaaaa
    60481 ctaaactcta atgaatctat cgccaaagcc ttacagttta tattattaaa agcttctata
    60541 tgcatttgat aacttacatc aacatcatca aaagctcctg ccttaactaa atcacatttt
    60601 cctcctgttg tttcttcagc tggtgttcct attagtacaa tttttccttt aaaattttct
    60661 tttaacttac ttaatactat acaagctcct agtgtagatg ctgcaatcca gttatgtcca
    60721 caagcatgag ctggttcttt attttctcca tatccaggaa gtgcatcata ctcagctaaa
    60781 aatgctatgg taggtccatc attatctcct aattcagctc taaaagcagt ctccatatta
    60841 caatatggat aaactgtatc aaatccatat tccttcattt tttctactaa gtattttgat
    60901 gatatgtatt cttcttcccc taattcagga ttgttaaata taaaattaca aacttcttca
    60961 atttcttttc caagttcatt ctctatctca taagctctct tctttatact ctctatcata
    61021 atttacctcc tactagaatc ctagatataa tcctattgtc aaaaatgcca ttacaagaat
    61081 tgttaatact accattaaag gaattacgaa tctaacccac tttgaccaag gaatattggc
    61141 tactgctagt gctcccatta aaacacctga tgtaggtgtt atcaagttag ttacacctat
    61201 accaaattga taagctgtaa ctatcatttg tcttgataca tctactaagt cgccaagtgg
    61261 tgcaagtaca ggtattgtaa gtgatgcaag ccctgatgct gatggtatta aaaatgctat
    61321 taatccttct attaagaaag ttaaatttat aaatatagtt tttggtaatc catttaataa
    61381 atttgctgca gaatttaaaa ttgtatctat tataaatcca ttttctgcta ttattacgat
    61441 tccacgtgca aatgctatac acaatcctgc tgtaattaaa tctcctgctc cacttataaa
    61501 tgaattaact atctcatctt gtttaagccc tgatgctatt cctgatatta tacctatagc
    61561 tgtaaatatc attgcaattt cagttatgta ccattctagt cttaaaactc catatatcat
    61621 aatcgccata cctattgtga aaatggctat taccatggct tctctttttg taaattcctt
    61681 tatatttgta tcactattaa ccattaattc ttgatttagt gatatatcat gtactaaaga
    61741 ttttttaggg tcttttttaa ctttattggc atacatcata acaaatccta tagatatagc
    61801 catatatatt ataaacataa caactctaaa ctctattcca gaacctggta ctatttgtga
    61861 taatgcttgt gctattccta cagagaaagg attcgtagta gctgctccaa atccagctgt
    61921 tgctcctata aatactgtgg ccactgctgt caatgaatca tatcccatac tggtcataag
    61981 tggaataaat atcatataaa aaggtagtgt ctcttcactc attccaaacg tcgtcccacc
    62041 tagtccaaat agaatcattg aaatcggtat tattaaaaat tgaaacttct tcattttatt
    62101 tacagtatga gctataacag cttctatagc tcctgtttta ttaactatcc caaaagctcc
    62161 tccaactatt aaaacaaatc caactacttc agctgcatct ataaacccgt ttataggtgc
    62221 tgtaaataca tcagtaattc cttgtggatt tgatggtgct ttttcataag ttccagctac
    62281 aacaactgac cttccgtcta tatctactct ttcaaaattt ccacttggca ctatccaagt
    62341 aagaattgcc attaacacta ttagcaaaaa tattattgta agtgtctgtg gcatagtaaa
    62401 ctttttcttt tttaaactgc tcatttttaa tctccccact ttttaaatta aatattttat
    62461 tattgcatcc ctttatccta ttttgtatag atgtaaaaaa gctcaacatg gatacatgtt
    62521 gagctaaatg tgctaaatac aacatacctg catcttccct ttatcttgtt taagatagct
    62581 ctccatcaaa attcgggata attttgatga cagtactgta cctattaaat acagtcccag
    62641 cactagcttc ggacactagc acttcggcac ttactccttt tatattgcct cattggtttc
    62701 caacctcttc aatattaatc ttagtaaatg caacctctac ctcaatctgt ttgttagatg
    62761 aggtaattct tattaatttt tattaattca aagtaattgt agcataatat gtcgagattg
    62821 taaatatttt cagtataata attcttactt tatgatttca ttccattttt cacaaataat
    62881 tttttctcca tataatttaa atactgtagt atattttaaa tacacacaaa ctttccacaa
    62941 attttaaatt attataatac ctttataata aaaaataaaa gctatgtaaa cttatcaatt
    63001 tacacagctt tatatacatt aatctactcc aagtacagct ttaagctttg atgctattgt
    63061 aataactcgt ggaccaaata taacttgaac tgagtttttc tttttaacaa ctccacttgc
    63121 acccaattca tttacccaga agccatcttc atagaatcca tcaattgaat ttagctctac
    63181 cctaagtcta gttgcacagt ttgtaacatt ttttatatta ttacttcctc ctaaaccttc
    63241 tattatagaa tgtacaagct ttgtatcttt atcatctact tcctcttcta ctgcattgtt
    63301 gtatgctgtt ttaccagcat ctacagattg tctttctcta tattctttct tactataaag
    63361 cttaacttct tctgaacttc ttcctggtgt ttttatatca aacttcttga ttgcccatgt
    63421 aaatattata taagtaacta taaaaaatat tggtatcaaa aataataatg gtaacgcatc
    63481 cactttttgt ggttgtaata aattaggaaa catatttcta aatgattctc ccattataga
    63541 aacattaaac atttctgtaa atacatacgt caatcctgcc agtggtacat atgctacaaa
    63601 atacaataat ggtgcaacaa ataggaatgt atactctatt ggttccgtta cccctaccaa
    63661 catggctgtt actattgctg gtatcaatat acttattgct tttttcttat tagcattatc
    63721 agccaactta tacatagcta aagctgctgc tggtaatatt gcaaaatgta ttaataaacg
    63781 acctgttgtg aagttacgag ttatataaga tagtgtatct gggtctccca tttgagctaa
    63841 tcttatatta ttaacaccct cgtaaattgc tccacctact tccattgttc cacctactct
    63901 tgtatattct atagggaatg caattaagtg atgtatacca aatggtaata atgctttatc
    63961 cattgctcca aaagtaaatg ttcctaataa tccactagaa cctatccaat taccaagttt
    64021 agataatgcc aaccctactg gtggccatat aaagtacatt gctgtaccca atactattga
    64081 tgctataaac atcataatca ttgaaaatct tggacctgag aaaaaagata atgcactagg
    64141 aagttctatg tcaacaaatt tgttatgtac tgcactagct acaaatccag ctattatagc
    64201 tccaaatata ctacaatcat atgaaaagat tcctaagaaa gaaccatata aagaacttcg
    64261 actatatgct tctgcctctc ctaatccaga tgccataaac gcttctgctg taactgtatc
    64321 tgaatttata ccatttgctg ctaacaatgt acttataact gtgtgcattc ctataaataa
    64381 aacaattcct cctaatgcac cccatccttt ttccttttta gataatccaa aggctatacc
    64441 tgtaacaaag aatattggta agtatctcat taccataaat cctaaatcgt ttattacttt
    64501 aaagaataca tttataaatg acccttcttt tattagtccg ctaagcccta atgcagaaac
    64561 gttttccata tttgcaaaag ctgaccctaa tcctataaat actcctgcta caacaagtaa
    64621 tataacaggt atcatcattg ctccagaaag tacttgtaat ttatccttca tagtattatt
    64681 tcctccattt ttattgaaat gccaggctat ataatgcata tatatatact tctattgctt
    64741 tgtataatgt atctatactt atattttcat ttgcctgatg tgaatttgga ttatccccct
    64801 ctattgtggg tccaaatgca actccatttt ttaacactct tgcataagat gcagctcctt
    64861 ttgtaaaaag ttcggcttct tttccaaaac cttgtttata tgcatttgat aatttattta
    64921 ttaattcact atctggtttt acatacagta attttaaatc cttatatata tcaactatta
    64981 aattttcttt ttttccaatt tcattaattc tattagttat aaactcccaa cttataccct
    65041 taggatatct aaagtctatt ttcatattca attcattttt ctctaagaag atactcatta
    65101 tacatattgt agaaactccc atatctacat cttctttata catccctaat ttttttccat
    65161 gattatcatc tgtaaagtat gaatttaaaa tatcccttat tataacgcct ttatcattta
    65221 gttttttaat tttctctaaa tcttttgcta aactaaatgc acagttatat gacctgtgtg
    65281 gatttctcga taaagccctt tctcctgtat atcttactaa tactttacct tcatctaatt
    65341 cttctatctc tgtataataa gctaatgatt ctactaaatc tttcttatca ttagttttaa
    65401 aaacagcctc aattttgtca catacaaatc catcttcttt gtttgacttt atatcaacta
    65461 aattgtgatt tctaaattta tctttatcta ttttctttct tagattgaag tataaaatac
    65521 ctttttctcc atttactatt gggaagtttc catctggaga aaatgcaaat tttggctgtt
    65581 cattgacact aaagtaatgc tccatacatt cccaagtcgt ctcttcagct ccacccacta
    65641 tcaatctaat ctttctcttc ggcttttcat taagttctct taagaaaagt aatgcatata
    65701 aaatccctat caaaggtcct ttgttgtcat taactcctct accataaaga tagttatctt
    65761 tttgacatac tttaaaaggt ttactcttcc aaagttcttt attatatatt ggcaccacat
    65821 ctatatgatt aagcacccct actacttctt ctccttctcc atattctata tgaattgcat
    65881 atccatcaaa gtcttttaca acaaaatctt tgtcttttgc tatttgaata agcttatcga
    65941 aggcatttct tatttctatc ccaaatggtt gatttatatc tgttgtactt tcatctctaa
    66001 ttgaaggtat ttcaactaaa cttctaatat catttatgat attttcttga ttggatttta
    66061 aataatcaat aattagttct ttgtttacta tcatcttaat tatttatcac ccctttatat
    66121 taattttaca aagcatttca gttcatatct acattataaa ttttgaatat tattttttca
    66181 atatttcaaa tacttctcta agttaccata atgatacggt aaacaatcaa cagattatga
    66241 caaaatcata ctatacctat tactaatatt ttaacttatc tattacgtct tttttaatgt
    66301 aagtttattc caaaaataca taaaaaaaga tgtagcctta gctacatctt cttatatcta
    66361 ttcaacttcc attattatgc tattaatatc tacatttcca ggttctatcc tatcttttac
    66421 tgttctctta acagaatcag catcatccat tataactaca ggagttatta tatttaaatc
    66481 atttgacgtt ataaaatcta aatctacttc cattattaaa tctttagctt ttaccttatc
    66541 tcctgccttt accttaacat caaacggctt tccttctagt gacattgtct ctaaacctac
    66601 atgtattaat atatttgtat tatcattact cttaatcatt attgcatgct ttgtatcaaa
    66661 tacattgact atttcaccat caacaggaga atataactta ccttcacttg gtattattgc
    66721 tactccatct cccatcatct tttgggcaaa aactgcatct ggaacatctt ctaagttcac
    66781 taaatttccc ttaaaagggc tatatatttt ctcaatctta ttttcttttt tcttaaatat
    66841 attaaacata acacactctc cacattataa aattttatga taatattttt cttaaagctt
    66901 ttgctacacc atcatttaca ttagtatcag ttacaaaatc tgccatagat tttacttcat
    66961 ctgtagcatt tcccatagca ataccaagac ctgcaaattt aatcatggat atatcatttt
    67021 cattatcacc tatacaaata acttctttgc tatctatacc taatatatca caaaattttt
    67081 taactgcaat accttttgaa gtacctttac tcataacttc aaagtttatc tttccagaac
    67141 ttactacttc taaatcttct tgttttttaa attcttcctt tgcttctctc aaagaatcta
    67201 cgttttctga gaaaagtata cattttaaaa tttcattatc agctttttct aataaagttt
    67261 cacaacttgc attttctatt atttcaattc tgtcttcttc tttattttta ctatttatta
    67321 atctatatgg atgttcttca cctatttcat tgttggatat aactatttta cagcctttaa
    67381 aatgtttgtt taaattatac ttttcaccta ttgtatagat tttctttaga gcttctttgc
    67441 tcaaaacctt cttatactca tatcccagta atttaaaata tgtcccatta gttgatataa
    67501 tatatatatc atcccctaaa acacttgtaa aatatttcat agcattataa ggtcttcccg
    67561 taactaaggc taccttgata cccttttcca tggcttcttt tagtgcttta atattttctt
    67621 ctgatacttc aaatccttta cccatcaaag taccatccat atcagtacaa attaatttat
    67681 atcgcatttg tatcacatcc tagtaagatt tttctaatat ttcaacaagg tcttctttct
    67741 ttccaaaagg taaaaatcct aaaactggac agcttgttat ttgttctaat tgttcctttg
    67801 ttacattaaa ctcagacatt tttgtcttaa gccccactct ctttaaaaaa ctttctattt
    67861 catttcctaa agttttagct gcttcatcat cttccacttt ttctaattct tggtttagta
    67921 ttctcgctac tttggcaaat ttctctatat tatccttata gaacttttct gcaaattttg
    67981 ggaacactat agccaaagcc tcaccatgag gaatatgtgt aactcctcct attatttcac
    68041 ttagtggatg tggtgctgct gctccagcat ttgccagtga acttcctcct aatgtatctg
    68101 ctactgctaa ctttgttctg tattctatat tatttttatc ttccattact ttaggtagat
    68161 agttaatgac taattccata gatttttcag acattatctc tgtaaaatca ttagcatttg
    68221 gatttatata actttcaaat gcatgagtaa aagcatcaaa tgctgttgat gcagtaattc
    68281 tctctggcag agttaacata agctctgggt caactataca ttcttttgag aaacaatttt
    68341 gatgaaatat tgtatttttc tcgcttcctc tcgatattac tgctgcttgt gtaacttggc
    68401 ttcctgttcc agaagtagtt gatacagcta ttaatggtaa ttctttttca cttaccttat
    68461 cgtatatttt aaatggattt gtatatgtac taaacatata atcccaatct attttttcta
    68521 aaccaaaagt caatgctaat acttttgcag tatctatact tgaacctcct ccaacagcta
    68581 aaacaacgtc tacagattct tttttagcta attcaaaccc ttcgtttatt aattctacag
    68641 ttgggtttgg ctctactctc tgaacctccc atgactaaag tcacagggtt cctgcttcac
    68701 agaattttgc atactaaaat atgtcttact aattctccac aggccatccc cgtagttcct
    68761 acggttctta cataagttat ttattttgaa ttgttattag tcttaatcct tcttttaata
    68821 tatttatact tgcatttata tctctatcgt gagtttcatt acaactagga caaatccatt
    68881 ctcttatatt taagtccttc acttcctcgt ttttataccc acatttattg catatttgtg
    68941 aacttgcaaa gaatttacct acctttacaa tttgtctacc atgccaatta gccttgtatt
    69001 ctaattgacg aataaattct gaccatgata catctgaaat tgagcgagat agtttacgat
    69061 ttttaatcat attctttact tgtaaatctt ctatgcaaat aatatcattc tcttttatta
    69121 atttagtaga taatttttg
//
LOCUS       DAYAKB010000016        63756 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.016, whole genome shotgun sequence.
ACCESSION   DAYAKB010000016 DAYAKB010000000
VERSION     DAYAKB010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.016"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..1184)
                     /locus_tag="ACGI3L_001195"
     CDS             complement(<1..1184)
                     /locus_tag="ACGI3L_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFG9196920.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNLAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDV
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DI"
     gene            1647..2843
                     /locus_tag="ACGI3L_001196"
     CDS             1647..2843
                     /locus_tag="ACGI3L_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFG9196921.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            2936..3460
                     /locus_tag="ACGI3L_001197"
     CDS             2936..3460
                     /locus_tag="ACGI3L_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFG9196922.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            3485..3661
                     /gene="rpmF"
                     /locus_tag="ACGI3L_001198"
     CDS             3485..3661
                     /gene="rpmF"
                     /locus_tag="ACGI3L_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFG9196923.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            3868..4425
                     /gene="fapR"
                     /locus_tag="ACGI3L_001199"
     CDS             3868..4425
                     /gene="fapR"
                     /locus_tag="ACGI3L_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045717 - negative regulation of fatty acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HFG9196924.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            4436..5458
                     /gene="plsX"
                     /locus_tag="ACGI3L_001200"
     CDS             4436..5458
                     /gene="plsX"
                     /locus_tag="ACGI3L_001200"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFG9196925.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            5484..6470
                     /locus_tag="ACGI3L_001201"
     CDS             5484..6470
                     /locus_tag="ACGI3L_001201"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFG9196926.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            6579..7508
                     /gene="fabK"
                     /locus_tag="ACGI3L_001202"
     CDS             6579..7508
                     /gene="fabK"
                     /locus_tag="ACGI3L_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HFG9196927.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            7524..8474
                     /gene="fabD"
                     /locus_tag="ACGI3L_001203"
     CDS             7524..8474
                     /gene="fabD"
                     /locus_tag="ACGI3L_001203"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFG9196928.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            8474..9223
                     /gene="fabG"
                     /locus_tag="ACGI3L_001204"
     CDS             8474..9223
                     /gene="fabG"
                     /locus_tag="ACGI3L_001204"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFG9196929.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            9277..9501
                     /gene="acpP"
                     /locus_tag="ACGI3L_001205"
     CDS             9277..9501
                     /gene="acpP"
                     /locus_tag="ACGI3L_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFG9196930.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            9530..10768
                     /gene="fabF"
                     /locus_tag="ACGI3L_001206"
     CDS             9530..10768
                     /gene="fabF"
                     /locus_tag="ACGI3L_001206"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFG9196931.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADLMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            10994..12712
                     /locus_tag="ACGI3L_001207"
     CDS             10994..12712
                     /locus_tag="ACGI3L_001207"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9196932.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            12743..14743
                     /locus_tag="ACGI3L_001208"
     CDS             12743..14743
                     /locus_tag="ACGI3L_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9196933.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            15094..15339
                     /locus_tag="ACGI3L_001209"
     CDS             15094..15339
                     /locus_tag="ACGI3L_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HFG9196934.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            15374..16099
                     /locus_tag="ACGI3L_001210"
     CDS             15374..16099
                     /locus_tag="ACGI3L_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFG9196935.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            16121..17434
                     /locus_tag="ACGI3L_001211"
     CDS             16121..17434
                     /locus_tag="ACGI3L_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9196936.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKIYGENLKKIV"
     gene            17640..18179
                     /locus_tag="ACGI3L_001212"
     CDS             17640..18179
                     /locus_tag="ACGI3L_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFG9196937.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            18268..20253
                     /locus_tag="ACGI3L_001213"
     CDS             18268..20253
                     /locus_tag="ACGI3L_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HFG9196938.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            20477..21445
                     /gene="spoIIIAA"
                     /locus_tag="ACGI3L_001214"
     CDS             20477..21445
                     /gene="spoIIIAA"
                     /locus_tag="ACGI3L_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HFG9196939.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            21435..21956
                     /locus_tag="ACGI3L_001215"
     CDS             21435..21956
                     /locus_tag="ACGI3L_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HFG9196940.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            21973..22170
                     /gene="spoIIIAC"
                     /locus_tag="ACGI3L_001216"
     CDS             21973..22170
                     /gene="spoIIIAC"
                     /locus_tag="ACGI3L_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HFG9196941.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            22195..22572
                     /gene="spoIIIAD"
                     /locus_tag="ACGI3L_001217"
     CDS             22195..22572
                     /gene="spoIIIAD"
                     /locus_tag="ACGI3L_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HFG9196942.1"
                     /translation="MQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVMFKL
                     NFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEFGGK
                     IIVMSMSFPILLSIVEMVVNIIP"
     gene            22657..23862
                     /gene="spoIIIAE"
                     /locus_tag="ACGI3L_001218"
     CDS             22657..23862
                     /gene="spoIIIAE"
                     /locus_tag="ACGI3L_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HFG9196943.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            23922..24539
                     /locus_tag="ACGI3L_001219"
     CDS             23922..24539
                     /locus_tag="ACGI3L_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HFG9196944.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            24551..25105
                     /locus_tag="ACGI3L_001220"
     CDS             24551..25105
                     /locus_tag="ACGI3L_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HFG9196945.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            25132..25821
                     /locus_tag="ACGI3L_001221"
     CDS             25132..25821
                     /locus_tag="ACGI3L_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HFG9196946.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNVDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            25931..26293
                     /locus_tag="ACGI3L_001222"
     CDS             25931..26293
                     /locus_tag="ACGI3L_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFG9196947.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            26378..26884
                     /gene="nusB"
                     /locus_tag="ACGI3L_001223"
     CDS             26378..26884
                     /gene="nusB"
                     /locus_tag="ACGI3L_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFG9196948.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            26868..27938
                     /locus_tag="ACGI3L_001224"
     CDS             26868..27938
                     /locus_tag="ACGI3L_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HFG9196949.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            27935..29140
                     /gene="xseA"
                     /locus_tag="ACGI3L_001225"
     CDS             27935..29140
                     /gene="xseA"
                     /locus_tag="ACGI3L_001225"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFG9196950.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            29142..29357
                     /gene="xseB"
                     /locus_tag="ACGI3L_001226"
     CDS             29142..29357
                     /gene="xseB"
                     /locus_tag="ACGI3L_001226"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFG9196951.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            29360..30247
                     /locus_tag="ACGI3L_001227"
     CDS             29360..30247
                     /locus_tag="ACGI3L_001227"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFG9196952.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIGKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            30277..30714
                     /locus_tag="ACGI3L_001228"
     CDS             30277..30714
                     /locus_tag="ACGI3L_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HFG9196953.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            30748..32613
                     /gene="dxs"
                     /locus_tag="ACGI3L_001229"
     CDS             30748..32613
                     /gene="dxs"
                     /locus_tag="ACGI3L_001229"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFG9196954.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            32746..33558
                     /locus_tag="ACGI3L_001230"
     CDS             32746..33558
                     /locus_tag="ACGI3L_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HFG9196955.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            33578..35257
                     /gene="recN"
                     /locus_tag="ACGI3L_001231"
     CDS             33578..35257
                     /gene="recN"
                     /locus_tag="ACGI3L_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFG9196956.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            35471..36337
                     /locus_tag="ACGI3L_001232"
     CDS             35471..36337
                     /locus_tag="ACGI3L_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196957.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(36430..36909)
                     /locus_tag="ACGI3L_001233"
     CDS             complement(36430..36909)
                     /locus_tag="ACGI3L_001233"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9196958.1"
                     /translation="MAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQDFNNE
                     LKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKIGKIL
                     LEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYMELKL"
     gene            complement(36982..37422)
                     /locus_tag="ACGI3L_001234"
     CDS             complement(36982..37422)
                     /locus_tag="ACGI3L_001234"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9196959.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            37583..38641
                     /locus_tag="ACGI3L_001235"
     CDS             37583..38641
                     /locus_tag="ACGI3L_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HFG9196960.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            38783..39607
                     /gene="spo0A"
                     /locus_tag="ACGI3L_001236"
     CDS             38783..39607
                     /gene="spo0A"
                     /locus_tag="ACGI3L_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA];
                     GO_process: GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HFG9196961.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            40020..41141
                     /gene="steA"
                     /locus_tag="ACGI3L_001237"
     CDS             40020..41141
                     /gene="steA"
                     /locus_tag="ACGI3L_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytokinetic ring protein SteA"
                     /protein_id="HFG9196962.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            41159..42034
                     /locus_tag="ACGI3L_001238"
     CDS             41159..42034
                     /locus_tag="ACGI3L_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HFG9196963.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            42058..42750
                     /locus_tag="ACGI3L_001239"
     CDS             42058..42750
                     /locus_tag="ACGI3L_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9196964.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            42758..43582
                     /locus_tag="ACGI3L_001240"
     CDS             42758..43582
                     /locus_tag="ACGI3L_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HFG9196965.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKNLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIVFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            43587..44654
                     /locus_tag="ACGI3L_001241"
     CDS             43587..44654
                     /locus_tag="ACGI3L_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HFG9196966.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQKAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            44656..45192
                     /locus_tag="ACGI3L_001242"
     CDS             44656..45192
                     /locus_tag="ACGI3L_001242"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9196967.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            45260..45865
                     /locus_tag="ACGI3L_001243"
     CDS             45260..45865
                     /locus_tag="ACGI3L_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HFG9196968.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKSR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            45877..46791
                     /locus_tag="ACGI3L_001244"
     CDS             45877..46791
                     /locus_tag="ACGI3L_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9196969.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAAEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            46833..48005
                     /locus_tag="ACGI3L_001245"
     CDS             46833..48005
                     /locus_tag="ACGI3L_001245"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFG9196970.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIEGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            48052..48864
                     /locus_tag="ACGI3L_001246"
     CDS             48052..48864
                     /locus_tag="ACGI3L_001246"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFG9196971.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            49068..50393
                     /locus_tag="ACGI3L_001247"
     CDS             49068..50393
                     /locus_tag="ACGI3L_001247"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFG9196972.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            50606..51685
                     /gene="mltG"
                     /locus_tag="ACGI3L_001248"
     CDS             50606..51685
                     /gene="mltG"
                     /locus_tag="ACGI3L_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFG9196973.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFSYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            51857..52531
                     /locus_tag="ACGI3L_001249"
     CDS             51857..52531
                     /locus_tag="ACGI3L_001249"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFG9196974.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRKYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            52518..53765
                     /locus_tag="ACGI3L_001250"
     CDS             52518..53765
                     /locus_tag="ACGI3L_001250"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFG9196975.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEIYEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            53837..55507
                     /locus_tag="ACGI3L_001251"
     CDS             53837..55507
                     /locus_tag="ACGI3L_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFG9196976.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDIDKSMKKELEKNGIMVEEKTMRYAKDGL
                     LSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKT
                     VDNKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQND
                     ISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNT
                     NEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGL
                     DEEKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNM
                     NTIKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLN
                     KKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(55604..55888)
                     /locus_tag="ACGI3L_001252"
     CDS             complement(55604..55888)
                     /locus_tag="ACGI3L_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9196977.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(55911..57428)
                     /locus_tag="ACGI3L_001253"
     CDS             complement(55911..57428)
                     /locus_tag="ACGI3L_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9196978.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKAYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(57553..58374)
                     /locus_tag="ACGI3L_001254"
     CDS             complement(57553..58374)
                     /locus_tag="ACGI3L_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9196979.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            58565..59992
                     /locus_tag="ACGI3L_001255"
     CDS             58565..59992
                     /locus_tag="ACGI3L_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HFG9196980.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISVNALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKIVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTVAKNNAIVLVDNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKVYN"
     repeat_region   60948..61240
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=60948..60976
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(61527..61751)
                     /locus_tag="ACGI3L_001256"
     CDS             complement(61527..61751)
                     /locus_tag="ACGI3L_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9196981.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            62462..62617
                     /locus_tag="ACGI3L_001257"
     CDS             62462..62617
                     /locus_tag="ACGI3L_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HFG9196982.1"
                     /translation="MALDVKIEVKIIKDVVILNITHWKKETSLLTVKIARSQGDLSYV
                     KYFANES"
     gene            62896..63114
                     /locus_tag="ACGI3L_001258"
     CDS             62896..63114
                     /locus_tag="ACGI3L_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196983.1"
                     /translation="MKILQQFKPYKYDKEKNIEYDEKIIANQNTEVYIVYPRISDEEN
                     RRRWEEFNEVAKEVAINIAMKKVETVES"
BASE COUNT        25511 a         6588 c        11438 g        20219 t
ORIGIN      
        1 tttatatcat aacttatgag tgttttaaaa atcgtatcat ctaatgaaaa tgatatattt
       61 gaaaacttgt ttattatttt tatttcagat ttatttttta tctcttttag aatttctcta
      121 cctttatcat taaaagcaag tattcttata taaggtatag tatctatgtt ttttataagt
      181 tgcacgtcgc tttttttaat acctaacaat atattgttta gagttcgttt gattttggtt
      241 aaagtgtatc gcttggattt aattgctaat tgtagttcat gtagaaattc agatgtaaag
      301 atatctttat agattctgtt ttctatgcct tcatttactt caaaatactc ttttaaagtg
      361 tccatatctc taagtataat tgtttttaaa atatcaaaga agaagtcatc aaacataggt
      421 aaaaaaccat tatctatttt ttcatttagg atgttataag ttttttctgg aataacattt
      481 tttaaatgaa aaaggtctgt attttcttta agtgaagttc ttatagcagt agcagaacaa
      541 atatcactct caatttcttc ggaattatat tctgattgga ccctggagat agtaaatggt
      601 tttatactac tgtttaaatg gatgaggttt tttatgtatt ctatacccag tatgttgttt
      661 gatgaattta atgtttttga taattgttcc tttgaataat tttgtataaa attatttttt
      721 ttgtcttgat gtatataatc aaaaagtgca ttagctctag ctgttggaaa taacagacca
      781 tcatctaaat atttttttaa aagtaactta aattcatttg gttcatttgc taaaatttca
      841 gctagattat aaagaatttc tgtatttcct tcttcactac caaaacatat agaatttatg
      901 cagtttagtg aatttaaaat tgttatagca ccatgagaaa aaatttcagc actttgacaa
      961 gcaaataaag ttggtaattc tataactaag tctacaccat tttcgacagc aatttttgct
     1021 ctagtgtatt tatcaaataa agctggttcg cctctttgta gaaaatttcc actcattatt
     1081 gctacagtat gtgttgcatt tgttttttct atagatttag ataaatgata tatgtgtcca
     1141 ttatgaaatg ggttatattc aactattaat ccaagtatgt tcataaaata ctccttttat
     1201 ctttaattat tttatatata tcacaattta ttataatatg tataaaattt aaatttttaa
     1261 ttataaaatt aaaaaacgta aaaaaattta taaaaatgta gaaatgttac ctacataaaa
     1321 aactggttaa atgttattaa aataacttta ttagctcttt atattatatt attataacaa
     1381 atgggaaaga ataatctaca ttaagttaac ttgttaatat attattagtg aaatacacaa
     1441 tttaccatac tagaaatatg atataatata aaaaaaaagt atatactttt atattaaaag
     1501 gtgatatatt atttatgaaa atcgtttaat gtatacaata atatatctat aacaaaataa
     1561 taaaagatag agttttattt agacatttat tacaaatcaa aatttattac atattattta
     1621 taaaaaaatc taaggaggaa ataataatga aaatattagt attaaactgt gggagttctt
     1681 cattaaaata tcaattaata gatatgaata atgaagaagt tttatgtata ggattggttg
     1741 aaagaatagg aatagaaggt tctatattaa aacatgaaaa agcaggtaga gatgataaat
     1801 acgttgttga acaaccaatg aaggaccaca aagatgcaat agcattagtt ttagaagctg
     1861 ttgctcatcc agaatttggt gcagttaaag aaatgaaaga aatagatgca gtaggacata
     1921 gggttgtaca tgctggagaa aaatttgcaa cttcagtagt aataactcca gaagtagaag
     1981 aagctttaaa agaatgtata gatttagctc cacttcataa tccagcaaac ataatgggaa
     2041 tagatgcttg taaagctata cttccagatg taccaatggt aggtgtattt gatactgctt
     2101 tccatcaaac aatgcctaaa tcttcatact tatatggttt acctcatgag ctatatacta
     2161 aatatggggt aagaagatat ggattccacg gaacttctca taattatgta tctcaaagag
     2221 cagcagagat attaggaaaa gatataaaag atttaaaaat agtaacttgt cacttaggaa
     2281 atggtgcttc tatagctgct gttgatggtg gaaaatgtgt agatacatct atgggattca
     2341 ctccattaga aggattaata atgggaacta gatgtggaga tatagaccca gctatattac
     2401 cattcttaat gagaaaagaa ggtttagatg ctgatggatt ggataaatta atgaataaag
     2461 aatctggagt atatggaatg actggaattt ctagtgactt cagagatata gaagatgcag
     2521 ctaaaaatgg agacgaaaga gctcaagcta cattagaagc gtatgttaaa aaagtacaaa
     2581 aatatatagg cgcttatgct gctgaaatga atggattgga tgttgtagta tttactgcag
     2641 gcgttggtga aaatggaaag gctataagag cagatattgc ttctaacatg gagtttttag
     2701 gaatgaaatt agataaagaa gctaatgatg ttagaggaaa agaaacagta atatctactg
     2761 ctgattctaa agtaaaaatg cttttaatac caactaatga agaattaatg atagctagag
     2821 atacattaag attggtaaaa taattaaatt aaacctatgc ctatcaagta aaaatacttg
     2881 acaaacaaat gctagatttg tataataaat ttggtgatat gttgaggtga acttaatgaa
     2941 agttagcata gaaaaaataa atagaaaaga aactgacaaa atagacttga atttttgtga
     3001 aaaaattgat actattagtt attgtgatga gatttacaaa ttagtatcac ctgtaaattt
     3061 aaaagggaaa gtgtcaaaga ctaataaagg tttgtatcta gatatagatg tcaattttac
     3121 aattgttgac aattgttcaa gatgtcttaa agaagtagaa ataccactag agtattctat
     3181 acaaggtttt ttagtaaaag aagaagatta tgatgaagat gagtttgagg aatttgatcc
     3241 ttttatattc gatggtgaag aaatcgacct tattgatata atagaacaga cattagattt
     3301 taatgtacct cataaagttc tttgtagtga aaactgtaaa ggtctttgtc aagtatgcgg
     3361 ggcaaactta aatgaagaag agtgttcttg cagtgaaatt acaaacgatg aggaatacat
     3421 agatcctcgt tttgctaaat taaaagattt atttaattaa attttgacta aggaggtggc
     3481 gtaaatggca gtaccaaagc gtaaaacgtc taaatcaaac acaaaaatga gaagagcagc
     3541 taactcaaag atggaagcaa caggatttgt aagttgccca caatgtcatg agccaaaatt
     3601 accacataga gtgtgtccag actgtggata ttataaaggt aaagaagttg tgtctaagta
     3661 atagcttcta aaaagcatgt agagtatact ctacatgttt tttttgtaca tataaaaaaa
     3721 taagataatt tactagagaa aataagtgga ttttatgcat attaaaaaat agaaaaataa
     3781 taatataagt attgaaaatt tttgtgtgtt actatatact actattagta gctggtacta
     3841 attacagcta taaaatttgg agggaacatg aaaaagaaaa gtaaagccca aagacaaaaa
     3901 gagcttatag atatgctaaa gacagatcct ttttatactg atgaagaatt atcaagtctg
     3961 tttgatgtaa gtatacagac cataagatta gatagaatga gtctaaacat accagagcta
     4021 agagaaagag tcaaatcaat agcagaaact cagagttcaa aagtaaagac tttaggagta
     4081 aaggaaatta caggagaaat cattgattta tctgtagggc gattaggtat atctatgtta
     4141 gaagttacac aggacatgat ttactctaag actaatactt taaaagatac gtatattttt
     4201 tctctagcag attcattggc aatggctata atagatgcac ctaaggttat tatgagagtt
     4261 gcaaatgtaa aaagttttaa gttgatagaa caacaagata ggcttatagc aaaagcagaa
     4321 gtgtatagaa atatagataa aaagcattat gtaaaagttg ttatcaacaa taaagcccaa
     4381 gagcaaatat ttagaggaaa gtttatcttt gaagaattag attaggaggg aaattatgaa
     4441 aatagtaatt gatggaatgg gtggagataa tgcacctaaa tctaatgtag aaggcgcagt
     4501 aaatgctata aaagaatatc aggttgattt aataatcaca ggagataaag atttacttga
     4561 aaaggaattt tcaaattatg aatttgatag aaataaatta gagatagttc atactactga
     4621 gattatagaa aacgaagata aaccagtaaa ggctataaga agtaaaaaag attcatctat
     4681 ggtagtagca ttaaatcttg taaaagaagg aaaggcagat gctataatat cagctggaaa
     4741 tacaggagcc ttacttgctg gtggattatt tgttgttggt agaataaaag gaatcgatag
     4801 accttgctta tgttcagcaa taccaaatgt aaagcgagga atgacactta tagcagactg
     4861 tggcgcaaat gcagattgta aacctaagaa tctagttgaa tttgcagcta tgagtaatat
     4921 ttattcaaga aaagttttag gtcttgaaaa tcctaaggta gcattagcaa atgttggact
     4981 agaagaaggc aaaggcaatg atttagtcaa aaggtcatat gaagaaatta aaaaattaga
     5041 tttaaatttt atagggaatg tagaagctag agaagttata aatgcataca cagatataat
     5101 catatgtgat ggatttacag gtaatatatt acttaaatct gctgaaggtg tagcactttc
     5161 agttatgagt cttataaagg aaacttttat ggccagtaca aaaagtaaaa taggagcatt
     5221 acttataaag gatgatttaa gaaaattaaa aagttttata gattattctg agtatggggg
     5281 agctccactt ttaggtctaa atggaggagt tataaaagct catggtagtt ctgatgctaa
     5341 agctataaaa aatgctataa atcaaggaat aaaattttca aagggaaaag tcgttgaaga
     5401 tattaaccaa tttataagca aatacaatga agaaaataaa aataacgaag atgaataaac
     5461 tcgttttgga ggtttaatat ataatgaata caaaggctgg aatattagga gtaggaagtt
     5521 atctacctga gcaatcatat gataattttc acttcgaaaa aataatggat acatcagatg
     5581 agtggataag tactagaact ggtattaagg aaagaagatt tgccaaagag tctgaagcaa
     5641 cttctgactt agcatctaaa gctgccttaa aagctataga atgtgcaaag ttaaacgtag
     5701 aggatataga gctgattata ttagctacaa ttactcctga tatgtctttg ccttcaactg
     5761 catgtatagt acaagatgca ataggagcag taaatgctac tgcatttgat atatcagcag
     5821 cttgttctgg atttgtatat ggagtaacta ttgcaaagca atttgtggaa acaggttgct
     5881 ataaaaatgt gcttgtaata ggagcagaaa cttgttctaa gtttttaaat tatgatgata
     5941 gaacaacagc agtattgttt ggagatggag ctggagcagc tgttattggc cctgtaaatg
     6001 agggtggaat actgtctaca catatgggct ctgatggtaa aggaaaagat tgtttaaaag
     6061 tacctgctgg aggttcaaga cttaaggcaa gtaaagagac tgtagaagct aatctacata
     6121 caatagaaat ggcaggtagt gatgtgttta aatttgcagt tagaaagatg gcagaaactt
     6181 ctttaagagc tcttgaaaaa gcaaatctaa atacaactga tatagactac ttagtgccac
     6241 atcaagctaa tataagaatc atacaagctt cttctaagag attagagctt gatatgaaaa
     6301 aagtttatgt aaatatagac aaatatggaa atatgtctgc tgcatctata ccagtagcat
     6361 tagatgaagc ttatagagaa ggtaaaatta aaaagggtga taatgtagtt ttagttggct
     6421 ttggtggagg tctaacttgg ggggcttcag ttgtcaagtg gactttatag tataaaatat
     6481 ctaaaatgat ttaattaaca aaattaaact tatacacaaa ataaagttga ttaataataa
     6541 aaagtttact tttatgattt caagtgaagg agaattgtat gaataaaatt tgcaaaatat
     6601 taaatataaa atacccagtt atccaagggg gaatggcatg ggtagctact gcatcattag
     6661 caagtgctgt atctaatgca ggaggacttg gcataatagc agcaggaaat gcaccaaaag
     6721 aagctataaa gaaagaaatt gttgagtgta aaaaattaac agataagcct tttggagtaa
     6781 atgtaatgct tatgtcgcca tttgttgatg atataattga tttgattata gaagaaaaag
     6841 ttcaagttat tactactggt gctggaaatc ctgcaaagta tatggataga ttaaaggaag
     6901 ctggaacaaa ggttattcct gtagtaccta caatagcttt ggcacaaaga atggaaaagc
     6961 taggagctac agcagtaata gcagaaggta ctgaaggtgg aggacatata ggagaactta
     7021 ctactatggt cttagttcca caagttgctg atgctgtaaa catacctgta atagctgctg
     7081 gaggaattgt agatggtaga ggaattgcag catcatttgc attaggtgcc agtgcagttc
     7141 aagtaggaac tagatttatt tgcagtgaag agtgttctgt ccattcaaac tataaaaact
     7201 tagtactaaa agcaaaagat agagatgcaa ttgtaacagg aagaagtact ggtcatccag
     7261 taagaacatt aaaaaataaa ctatcaaaag aatttttaaa gatggaacaa aatggagcta
     7321 ctcctgaaga actggataaa aaaggtacag gagctttaag atttgcaaca gtagatggag
     7381 acatagaaaa aggttcattt atggcaggtc aaagtgctgc tatggtaaaa gaaataacac
     7441 cttgtaagga aattatagag gctatggtaa atcaagcaag agagattatg ccagcaatag
     7501 aactgtaaat caggaggagc aagatgggaa aagttgcact agtattccct ggtcaaggag
     7561 ctcaatatgt aggtatggcc aaggatttat atgaaaataa tgctgttgct aaaagtgtaa
     7621 tagatgaggc tagtgatgcc ttaaatatgg atttaaaaaa ccttatgttt aatggaaatg
     7681 aagaagaact ttctaaaact gaaaacactc aacctgctat ggttacacat agtgtagcag
     7741 tattaaaagc ggtacaagct caaatagatt taaaatataa tgcatgctta ggattatcct
     7801 taggagagta tagtgcgttg gttgcagcag atgcaattga ctttaaagat gctgtatgtt
     7861 tagttaaaaa aagaggtaag tttatgcagg aaacagttcc agcaggtgtt ggagctatgg
     7921 cagcagtttt aggtttagat agaaatgtac ttgaaaatgt ggttaaagat atacaaggag
     7981 gtattgtaga agtagcaaat tacaattctc ctggacaaat agttatatct ggtgaaaatg
     8041 aaaagataga agaagcaatg gtaaaatgca aagaagcagg agcaaaaagg gcagttaaat
     8101 taaatgtaag tggacctttt cactcatcaa tgttaaaaga agctggtgta aaattggcca
     8161 gtgaattaga aaaagttaac ataactaaac ctaaagttga tgtggtggca aatgtaaatg
     8221 cagattacta taaaaacgaa ggtaaagacc tgcttataaa acaagtaagt tcatctgttc
     8281 tttgggaaga ttctatagaa agacttttaa atgatggata tgatactttt atagaaatgg
     8341 gacctggaaa aactttaaaa gcatttatta agaaaatagc ttccaataaa aaagcaaatg
     8401 tcaatattta taatatagat ggtatagatt ctcttaatga atttgtacaa aattatagaa
     8461 atggagagat ataatgataa atcttacagg acaagtagca gttgttactg gtggttctag
     8521 gggtatagga aaagaaatag caaaaaaact agcatctttt ggagctgatg tagtaatcaa
     8581 ttatacttct aaagaagatg aagcactaaa aactaaaaat gaaatagaaa gtatgggggt
     8641 aaagtgtacc tctataaaat gtgatgtgtc taaatttgat gaagtgaatc aaatgataga
     8701 ttctgttgta agcgaatttg gaaaaattga tatattggtt aataatgcag gcataactaa
     8761 agatggtctg cttatgagaa tgaaagaaga agattttgat agagttatag atataaactt
     8821 aaaaggtgtc tttaattgta caaaagcagt tactaaacct atgatgaaaa agaagtatgg
     8881 aagaataata aatatgactt cagtagttgg aattatgggt aatgcagggc aaactaatta
     8941 ttgtgcatca aaagcaggtg taattggatt tacaaaagct tctgcaagag agttagcatc
     9001 aagaaacata aatataaatg cagtagcacc tggatttata gaaacagata tgactaaagt
     9061 actaagtgat gatgtaaaag aatcaacact agcaaacata ccaaagaaat cttatggtaa
     9121 accagaagat gtagccaatg ccgtagcatt tttagttagt gacatgtcaa gttatataac
     9181 aggacaagta ataaatgtag atggtggaat ggtaatgcaa taataattta aaaagtagag
     9241 aaatctatta aaataaaaaa ttttaggagg tacacaatgt ttaataaagt tgtagaaata
     9301 ataatagagc aattaggagt agaagataaa gaaataacta tggaaacatc attaatgaag
     9361 gatttagaag cagattcatt agatgcagta gaaataataa tggcacttga agatgaattt
     9421 ggtatagaaa taccagatac agaagcagaa aacttcaaat ctataggaga tatagttaag
     9481 tatatagaag ctaataaata gtcgagcttt aaaaaagtgg aggtatccga tgaataaaag
     9541 agtagtaata acaggacttg gatgtgttac gccgttggga acaggaaaag aagagttctg
     9601 gagtaatata aaatctggag tatctggtat agataaaata actaattttg atgctagcac
     9661 atatcaaact cagatagcag gagaagttaa gaattttcat ccagaagaat atataagtaa
     9721 aaaggaattg aagagattag ataaatttgc tcaatttgca atagtatctg ctaaattagc
     9781 agttgaagat gcaaatcttg atttagataa agttgataga gaacgttttg gtgttataat
     9841 aggttctgga ataggtggag ttgaagctat agaaactcaa cataaaattc ttttggaaaa
     9901 aggaaataaa agagtaagtt cactttttgt acctatgatg ataggaaata tggcagctgg
     9961 tcaagtttca atatttttag gagcaaaagg acctaacact aatgtatgta cagcttgtgc
    10021 atcaggaact cattcaatag gtgatgcttt taaggtaatt caaagaggtg atgcagacct
    10081 tatggtagca gggggttctg aagctgctgt aacaggtctt gcttttgctg gattctgtaa
    10141 catgaaggct atgtcaacta gaaatgatga ccctaaaact gcatcaagac catttgataa
    10201 agacagagat ggttttgtaa tgggagaagg agcaggtatt gttatcttag aagacttaga
    10261 acatgcttta gcaagaggtg ctaaaatata tgcagaagta gttggatatg gtttaactgc
    10321 tgatgcatac catatgacaa ctccagctga aaatggagag ggagcagcta ggtctatgaa
    10381 tatggctttg aaagatggaa atgttccatt agaagaagta gattatataa atgctcatgg
    10441 aacttcaact tattacaatg atttatatga aactatggct ataaaaactg tatttggaga
    10501 aaaggcatat gacttatgtg tgtcatcaac aaaatctatg actggtcact tattaggagc
    10561 atcaggtgct atagaggctg ttgtttgtgc tatgagtata gaagatagtt ttgtgcctcc
    10621 aactataaac atacaagaag ttggtgaaga tttggattta gattatgttc caaatcaagg
    10681 taaagaaaaa aatattagat atgcactatc aaattcttta ggatttggtg ggcataatgc
    10741 tacaatagta ctaaaaaaat atgtataaat aaatattaaa tataaaacta aaaaacaagc
    10801 acttgtttta actgtataaa tttatattag cttaaattta aagtctccta aattatttta
    10861 ggagattttt ttattaagat ttaagtctag gatatgttgt aaatcatttt gatatattgt
    10921 attattaatt attaagaggt tatttatata tgcaagtttt cattctacaa tatacaaaag
    10981 gaggactaaa attttgaatt ttagactacc aaagaaaagg ttacccaaaa agataatttt
    11041 tatatgtata atacttatta gtattatttt gtttataaag tatgaccaaa atggattgaa
    11101 agaaagagaa attataaata agggaaaata tatgtctgaa agccttgtgg cagataagga
    11161 gtatgatgaa gcaaaaaaag tggttaagac ttcttttgaa tctattccag aaaaaaaata
    11221 caataaagta tataatgaag tttgggatat gttaaagact atttcatatg ttccagatgg
    11281 aacgaagata gtcattgatt ctttagaaaa gatgagagaa tcagatgtga aattatctga
    11341 tgaatgtaga tttaatatag aaaaaagatt agcatcagtg tatataatgg ataataatta
    11401 ttctaaggca gtagatttaa ctgtaaagtc tataaagttg gctgagaaat tggggaataa
    11461 ttatgaaaaa gcaagactag atgttgattt ggcgagcata tttttaaaga taggtggcta
    11521 tgaaacagga gagaaattaa taaaggattc ttttaaaata gatattgatg aaggtgaaaa
    11581 aaatggaatg gttagattat atgctattat aaatctagca gaaatatatg tagaagaggg
    11641 cgaatatgat aaagctattg aaataagtag caggataaaa gattataaaa agtttgtaaa
    11701 tacggataat tacaatgatt ttgatataat ggcctctata atgcagtcaa atgcgtatgt
    11761 gggcaaaaat aatatacaaa aggcaaagac ttttttagaa aaagctgatt atcttataaa
    11821 atcagataga acagtttata tattagataa agatatgtac tattatatgg caatgggaaa
    11881 cttagaatat aaaagcgaaa attataattc tgcaatagat aattataaaa aaagtttaga
    11941 gatatctact aaaagaaagt taacccagga gaaaataaaa aatttaaata agatattaaa
    12001 tatatatgaa aaacaaggaa atatagaatc tttaaatgag tatcaaaaga tgttaataaa
    12061 tgaatataaa gagaacaaaa gtataagaga ttcagagact agtttctata taattgataa
    12121 agtatcaaac gaaagtaagc tatttgaaaa aactaaaaaa gaaataaaat attataaaat
    12181 attatttaca gtaattttaa ttgctatatt agggtctact tttttataca accgattgaa
    12241 gtattttaaa gcacaaaatt tacatgatgg tcttacaaat gtttataata gaaaaagttt
    12301 tgatattatg tatgaaaagt acagagagaa agatgataat tttgcacttg tgatgataga
    12361 tattgataat ttcaagctca taaatgataa ttatggacat aaatttggtg acactgttat
    12421 aaagggaata acaaatacca tttgtgttat gttagaacaa gatgataaag tctttaggta
    12481 cggaggagaa gaattttctg tattaataag aaataaatct ggtgatgaag tagcagatat
    12541 aattgacagt ataagggttg caattgcaaa taaaaagtgg aatgatgatg tgactgtgac
    12601 tataagtgca ggtgtagctc atgtttcaga tagcaaagat gtactagaag aagctgataa
    12661 aaatttatat aaagcaaaac aacttggtag aaataaagta gtatataagt aattatatac
    12721 tatataaata agaggtataa atatgaaaca atcaatagct atagtaactg ataaaataac
    12781 taaactatca tctttcttag aagaaaatat acgtttggtt ttaggtaatt atattgatat
    12841 aaaccactat tatctggaag ttttaaaaga gaatgataaa atacaaggtg attttgtact
    12901 agtaatgaat gatgatagat taaacagtat gagaaagcat ttagtacaag atagtaagat
    12961 tatagtgata aggagaacac ttaaagaaaa tgaaatatat ggattatttt caataccaaa
    13021 tggaactgaa gtattggttg taaatgatac aaaagaaact accttagaaa cgataagctt
    13081 attttacaaa ataggagtaa aaaatttaaa gtttactcca tatattgaag gaaaaattta
    13141 taaaaatata gacatagcta taacacctgg agtaaaggga aaagtaccaa gttatataaa
    13201 taaagtaatc gaccttggaa atagatatat tgatatatct acctttatag aaataataaa
    13261 tggtcttaga atagatgtta aagaaatacg taaaaattta atggcatatt ctgagagttt
    13321 aataagttta gataatggag ttaaagataa ttataggcaa ctgtttttaa aaatagaaga
    13381 acaagatgtt atattgaatc tatcaaaaga tggaataata tttacttcag cagatggtat
    13441 aataaacaca tttaataaag aagctttaaa aattttaggt ataaatgaaa atccacaagg
    13501 caaaaacata gaagatatca tttctgaaga tttaaatatt ttacttgaag acaaagaaat
    13561 aattgatgaa gtggtattta caaataaaaa atatataaat gtaaataaaa aaagtatttt
    13621 ttctatgggg aataaagctg ggatatatta taacttacaa gaaataacgt atataaaaaa
    13681 attagaacaa aatcttacta ataaattaag agaacaaggt cagatagcaa gatatacatt
    13741 taaagatata aaaactaaaa ataaaaatat ggtaaagtgt gtagaattgg ctaaaaaaat
    13801 atctaaatca gacctttctg tattaataat aggagaaagt ggtactggta aagaattatt
    13861 atcacaatca attcataatg cttccaatag aagtaatcaa ccgtttatag cagttaattg
    13921 tgcagcagtt ccagatagtc tattagaaag tcaactgttt ggatatgaaa aaggctcttt
    13981 tacaggagct ttaagagaag gaaaaaaggg tctatttgaa cttgctaata atggaactat
    14041 atttctggat gaaattggag atatgcctcc attgctacag acaaagttac taagggtatt
    14101 acaagaaaag caggttatgc ctataggttc ccataatgtt ataaacatag atgttagggt
    14161 catagcagca acaaacaaaa acttactaaa gatgattaga gaaggaaaat ttagagagga
    14221 cctgtattat agactaaatg tattgccaat agatgtacca tcattgagga atagaaaaga
    14281 agatataata acacttatga atttcttttt gaaaaacaat ataagacttt cgccagaagt
    14341 tataactatt ttagaaaaat ataattggcc aggaaatata agagagttac aaaatgttgc
    14401 ttcttatgta agtctaatgt gtgatagtat ggtttttaga gatgacttac caccatatat
    14461 aagggtagaa tgtgctaaca attatgaaga tggatttggt tatacaagaa aagaatttga
    14521 ggaaatactg aggattctat atgaaagaag agagtcatcc tctggaattg gaagagggtt
    14581 tataatcgaa aagcttatac aggaaggtat tgagatttct gaaagcaaag ttagaaaggt
    14641 gctatcttat ttaagtgaat gtggatacat atcatctaaa tctggtagag gaggaagtca
    14701 aataacctca gaggggataa aactttataa taatataaat taagctaagt atttgatatt
    14761 gaaatcacat attttgaatt tagatattta aataataata aacttttata tttatagaga
    14821 ttaatttata ttatgtcaga aagaatattg taatttataa ttaaatatta ataggttttt
    14881 aaaataggat tagataggta ataggttaag ttagaataac ccattaccta tttttatttg
    14941 taagaaaagt gtacatagaa ttagaagtaa aaaatacaac taataaaact attgaaaata
    15001 ctagataaat aataaataaa aataattata gattttggca tacatattgc taattataga
    15061 gataagacga caaaataatt gggaggttta atgatgaaat acaaaacaac agggacttgt
    15121 gctacagaaa ttgaatttga agtaaaagaa aataaagtta caaatgtaaa ctttataggt
    15181 ggatgtgatg gaaatttaaa agggctaaaa gtattagttg aaggcatgaa tatagaagat
    15241 gtaatacaaa agttaaaagg aatagagtgt aaaacaaagc caacatcttg cccagaccaa
    15301 ctgtctctag cattggaaaa ttatatgaat ataaagtaat acataaaaca atcgattagt
    15361 taggagttta attatgaaac caataatagg gattttagga aatttaataa taatggaaaa
    15421 tggtatgttt ccaggtcttg aaaggtcata tgtaaataat gattatataa atgcagtgct
    15481 aaaaggtggc ggtagtccag taataattcc tgtaaataca gataaagaag ttataaaaaa
    15541 acagattgaa atggttgatg gagtcttaat atctggggga tgggatatca atcctcaact
    15601 gtatggagaa gaaacaagag aagaaacgac atttatatat ccagaagtgg atgaatttga
    15661 tttaattgca ataagtatag cattagaact taaaaagcct atattaggtg tatgtagggg
    15721 actacaaatt ttaaatgtaa gtttaggagg aactttatat caagataata atcttataga
    15781 aggaagttat ataaaacata cacaatcttc taaaagacat gtagctactc ataaagttga
    15841 tgttaaagaa ggaagtattt tagagggaat tttaggaaaa caattactta caaatagtta
    15901 tcatcatcaa agtgtcaatc agcttggaaa aggattaaaa gccatagcat actcaaaaga
    15961 tggtataata gaagctattg agaaagagga tgaaaatttt gtagtaggag tacagtggca
    16021 tccagaaatg atggtagatt actgtgataa aatggaaaaa ctatttaaat attttataaa
    16081 tatttgttcg aatttataat ataccttggg gggattgaac atgaacgaaa agaacaaaat
    16141 gggattaata agtattatac ttttaggtat taatgcagta gtaggagctg gagtttttct
    16201 attaccagga gatgcaatga aatcatttgg tgtagcaagt atatttgtat atatatttga
    16261 tatgttgtta gttttatcta tggcattctg ttttgctgag gttgcaggta aattcaataa
    16321 aaatggtgct gcctatgtat atacaaaaga agcttttgga gatttttgtg gttttgaagt
    16381 aggtcttatg aaatgggtaa taggatgtat ttcttgggga gctttaatag taggttttcc
    16441 tacatcatta tcagcagtat gggctccagc aggtgaacca catatacaaa aaattataat
    16501 tgtagctatg atagttgggc ttacaattat aaacttatta ggtgtatctc tatcaaaaat
    16561 tgtacaaaat gttataactg taggtaaact aattccatta atactattta taggaatagg
    16621 tatatttttt ataaaaggag ttaattttac ttcttcaaca atggtacctc caggagctgg
    16681 agcaacagag tttggagcag cagcactttt aatgttttat tcatttacag gatttgaatc
    16741 tatagcagtt gcagcagaag atatggaaaa tccacaaaaa aatataccaa tagcaattat
    16801 aagtgtaata gtaattgcat caataatata tatattaaat caagttgtat gtgttggtat
    16861 actaggagat tcgttatcta gtacatctac accagtggca gatgctgcaa gaatatgctt
    16921 tggaaatatg ggagctggat tggttacctt tggaacattg gtttctgttg gtggaatttg
    16981 tatgtgtggt gcttttgtaa atccaagaag ttgtgtagct ttagctgatg ataaaatgtt
    17041 accgagaata tttgcaagaa aagataaaaa aggtacacca tatgtagcga taatagctac
    17101 tatgttaatc actataccaa tagctctatc tggaagtttt gctgaattag cagcaataag
    17161 tgcagttgct agattcatac aatacatacc aacatcttta tccgtattag tgtttagaaa
    17221 gaaaagacca gaattagtag gtacttttaa aactcctttt ggagcagtga ttcctctaat
    17281 tgctgtatgt gttggaacat ggttgttatt ccaagcatct atgcatcaat taattatggg
    17341 attaggagct ttggcaattg gagtaccatt atactttata atgaagtctt ataatagaaa
    17401 aatctatggt gaaaatttaa agaaaatagt ttaattatgt tataacaatt tattgagtta
    17461 aaattagaca ttggcagaaa attaaataca aataagtatc tacaaggcta tattaaaata
    17521 ttattaattt tttattttaa tatagcctta tattgttatc aataaatgaa aaatattgta
    17581 acaacagaag aacaatagta ttatgtttat agacaaaaaa cttattagga ggtaaattta
    17641 tgccaacaat aacattaaaa aatggtgtag acgtacttat tagagaaggt gtaagagaag
    17701 atgctcaaag cattatagat ttttataatg aagtgggtgg agaaactcat tttctgtcat
    17761 ttggaaagga tgaatataaa atatctttgg aggaacaaga aaatgctata gaatcagcaa
    17821 aagcatctga taattctgtt aaactgattg catttataga tggtgaaata gttgggattg
    17881 caacgattga ttctaatcaa aaagcaaaag gaaagcatgt tggagtatta ggaattgttg
    17941 taaaagaaaa atattgggga attggattgg gtaaaaggct tatgttagac cttatagaat
    18001 ggtgtaaatc aaatggaata accaagaaga taactcttgt cactaatgaa gaaaattata
    18061 atgctatagg attatacaaa aaagttggat ttgaagtaga aagcatacta aagaaagaat
    18121 gttattataa tggtgtttat actgatttaa taggaatgtc acttttattg ggaatataat
    18181 tagtgtacat tttatctcga aaaaagtata ttaagtatgg tataattaaa aaagaatata
    18241 acttaatata attttggagg acgaattatg aaaaatctgt gtaaaatatc agatgattat
    18301 ttaaacagca agcttaagta tttaaagtta ttatcaaaac aatatccaag tatatcaaaa
    18361 gcaagtacag aaataataaa tttagaggct atattaaatc ttccaaaggg aacagagcat
    18421 tttataacag atgtacatgg tgaatatgaa ccatttgtac atgtattaaa aaatggttct
    18481 ggtgtaataa agagaaaaat agaagaattg ttttcaaata caataagaga cagcgaaaaa
    18541 aaaatgttag caactcttgt atattatcct gaacaaaagt tagacctaat aattaagcaa
    18601 gaggaaaata tagatgattt ttatagaata aatatttata gacttataga actttgtaaa
    18661 tatgcttcta gcaaatatac taggtctaaa gttagaaaac tgttaccaga aaattttaaa
    18721 tacataatag aagaactttt gcatgagcat gttaaaagtg aacataaaga agagtattat
    18781 aaaagtatag ttgaaacaat agttgacata ggaatagcta aggagtttat aattgctatt
    18841 tctacagtta tacaaaaatt ggttgtagat agacttcatg taataggaga tatttatgat
    18901 agaggtccaa gaccagatat aattgtcgat aagcttattg aacatcattg tgtagatatt
    18961 caatggggaa atcatgatat attgtggatg ggtgcagcct caggtgaaaa aacttgtata
    19021 gcaaatgcac tgaggatatc agctagatat gcgaatttag acattgtaga agacatatat
    19081 ggaataaatc tattgccttt agccactttt gctatagaaa tgtataaaga tgacccttgt
    19141 aaagaattta ttccaaaggt taatgaccaa agtgtaacaa caacagaaaa gtctttaatg
    19201 gcaaaaatgc acaaagcaat aagtataatt caatttaagc ttgaaggtga ggttatcaga
    19261 cgaagacctg aatttgaaat ggaacataga ctcttgctta atatgataaa ctatgatgaa
    19321 ggtacgatta atttaaaagg taaaacatat aaattaaaag atacttattt acctacaata
    19381 gacaaaaaag acccatataa attaactatg gaagaaagaa atgttattga taaattagta
    19441 tcttcattta gaggtagtga aaaactacaa aaacatgttt catttttgtt ttctaaagga
    19501 agtatatatt taaaggctaa ctcaaattta ctgattcatg gatgtgtacc gttaaatgaa
    19561 gatggaagct ttatgtctat gaatataatg ggaaaagagt ataaaggtaa ggctcttatg
    19621 gataagatgg agtctctagc aagagaagga tttttcttta aagataaggc agaagaaaaa
    19681 ctgtatggca tggatattat gtggtattta tggactggga aatgttcatc attatttggt
    19741 aaagatgata tgactacatt tgaaagatac tttatagctg aaaaagagac tcataaagaa
    19801 aataagaacc catattttaa acttagagaa aatgagatgg cttgtaaaag attatttgaa
    19861 gaatttgatt tagaacttga tgaatctcat ataataaatg gtcatgttcc tgtggagagt
    19921 aaaaatggag agagcccaat aaaagctaat ggtaaaattc tcgttataga tggtggtttt
    19981 tctagggctt accaaaaaac tactggtata gctggataca ctttgatata caattctaga
    20041 actttgcaat tagtatcgca tgaaccattt aattctgctg aagaagccat tgcaaatgaa
    20101 agtgatatct tatcgacaac tgttgtagta gagcataagg caaagagaaa aatggtgaga
    20161 gatactgatg aaggaataaa gatacaagag gaaatagaag atttaaaact acttttaatg
    20221 gcttataaga aagggctaat aaaagaaatg tagatgttat agaggcactt catgattgaa
    20281 gtgtcttttt gttaatactt attaaatata ttataaagat taataatagt agtttatatt
    20341 atacttacta agtgaatcca agataaatgg gttcactttt tttatttata aacattatta
    20401 aaaaaatata gatgttttgg ttatattcct tgtcctttat aaatagaatt atataaacaa
    20461 aggaggagga caagagatga ataaactttc tgatgaaata ataaactctc tttctacaac
    20521 tataagagaa aaggtagaaa aagtctcaaa caataatctg aacatagaag aaattaggtt
    20581 acgctcacaa aaaccattga tactaaatgc aaactctaaa gattattttt acaatcaaaa
    20641 aactatgaca cttgatttaa atcaacaaaa ctcatatgta gtaacaagag aagatgtaga
    20701 gcaaactttt caaataatat gtaaatattc aatacattca tttatggatg acataaaaaa
    20761 aggattcata actttgagag gaggtcatag agtagggtta gttggaaaag caatagtaga
    20821 agatggacaa gtcaaaaata taaagcatat atcatcttta aatataaggg tatcaaggga
    20881 aattattgga tgctcggata agattttaag tcatatcata aagggaaaaa atcagattaa
    20941 taatactttg ataatatcac cacctcaatg tggaaaaaca actttaataa gagatatagt
    21001 aagaaattta agtaatggta atgaagatta tggatttaaa ggtttaaaag tggctttagt
    21061 agatgagcgt aatgagatag caggagctta tctaggtgtt ccacaaatgg atgtgggaat
    21121 aaggactgat ataatagaaa cttgcccaaa agacttgggt attacaatgc ttttaaggtc
    21181 tatgtcacca aatgttattg tgacagatga aattggaagt gaaaaagaaa taaaggcatt
    21241 atacacagca ttaaatggag gtataggatt aataactact gtgcatggag attcaataga
    21301 ggatatacaa aatagaaaag aattaaatag acttctggat aaagagttat ttaaaaaggt
    21361 tataattctt tctgcaaaaa gaggagcagg aacaattgaa aaaatttatg atttagaaga
    21421 aaagagatgg tattttgcaa attaaaataa ttattatagc tttcttgata ggaagtagtt
    21481 atttgatagg tgaacaaata tacaaaactt atactcgtag acataaacaa ttaaacgatt
    21541 taataagagt tttagaaatt ttgaggatgg atttatcttt tggactttat acattagaag
    21601 aaatctttaa taggataggt ggaaataaag agttttgttt ttggaaattt ttctatcaaa
    21661 tatcagaagg acttcacaat gaacaaagta aaactttgga aataataata tcagaaaata
    21721 ttgatgtctt aagtaaagaa acttatctag gcaataaaga aattgaggaa ctgaaaaatc
    21781 taatacttac tttagggaaa agcgatatag agtcacaaca aagaatgata gatttatcta
    21841 tagaaaattt gaaaaaacaa acctatgaga caaaggaaga tataaacaaa aaaggcgtat
    21901 tgtataaaaa attagtgaca ttcataggta taggtatatg tattatattg atttaatatg
    21961 gggaggttta ttatggaaat atcattgata ttaaaggttg caggtgtcgg tattctaata
    22021 tcagtattga atatgatatt ggaaaaaaca gatagaaaag attgggcagg tcttactaca
    22081 ttagcaggtg taataatcgt attgggtatg gtaataacag aaataagtga cttgtttaat
    22141 actgtaagaa caatgtttca actttactaa agaggaggga gtaatttgga aataatgcaa
    22201 ttaataggaa ttgcaatcat ttcaactaca ctctgtttag taattaaaaa agatagacca
    22261 gagatagcaa atttcatagc tataataact ggagtaataa tactattgtc agttatgttt
    22321 aagctaaatt ttatagtaga tagtatacaa gatttggcta acaaggctaa catcccaact
    22381 atgtatatat cattaataat aaaattaatt gggatagcat acttaatgga atttgcgata
    22441 caactttgta aagattgtgg ggaaggaaac attgcttcaa aactagaatt tggaggtaaa
    22501 ataatagtta tgtcaatgtc tttccctata cttttgtcca ttgtagaaat ggtggtgaat
    22561 ataattccat agatgtgtat cttggaatga atataagtat attagagagc tttcgttgta
    22621 ttgaggttta tagagtgaag agaggcatgg ttgcttatga aaaaaagatt tttaccaatg
    22681 attataggtt ttttatttac tttctttttt gtaaatatct ttgctattat gatatttgct
    22741 aatgaagtac caagtagtga agataaagaa tatggtgaaa caaaaaatag catagataag
    22801 tatatagatg gtcaattaga caagctagat ataaatgaga ttcaagacta tataaataaa
    22861 gaaatagtta ttaatgatgt taatttaaaa tcatttgtaa aagatttaat tagtggagaa
    22921 aaaaatatct tagatttatt caataaagat ggattgaaga tattgatgtt tgatgaattt
    22981 aaagcaagtt taaaggtagt agcagtaatt ttggtactgg ctctgttatc atctatttta
    23041 aagagtctgg aaaactcttt ttcatcaggt gcagtaagtc aaatagcaac atatataata
    23101 tttatcacaa tggtatcact tacacttatt ggttttaaag atgtattaca gatttgctat
    23161 gatgcaatag accatactgt aggtcttatg caagttataa tgccaatatt aataacattt
    23221 ttacttttaa ttggattccc aataacgtcg actactttga atcctatctt cataggagga
    23281 gtaacattta taaatgtatt ttttaaaaat tttctatttg tatctattac tgttgcattt
    23341 ggaattttaa taataaacaa tttatcaaaa aatataaggc taaagagatt tttctccttt
    23401 gtaaaacaaa taaattatgt ttctattgga gctatgttta ctgtttactt aggtcttgta
    23461 tccatacaag gattgtatgt aaccagtttt gataaattca gtgtaaagac tgctaaattt
    23521 gctataggta attttattcc tgttgtaggt ggatttgtat ctgactctgt ggatatttta
    23581 ttatcttcat ctcagcttat aaaaaatata tttggaggaa taggacttat cttacttgtt
    23641 ggaatttgct tacttccagt aataaaaatt ttatcagtaa tagtagtgta caaattagca
    23701 gcaataattg tagagcctgt tggagaggat ggaatatcta attttttaaa tgaagtggca
    23761 aatttaatga taataatgct agcatcagta attgctataa cagtaatgtt ctttgtaact
    23821 gtagctatct tgacctcgat aagtgtcgta agtcaagggt aatttatata tcagtgaaaa
    23881 ataattacat ttaatctaat gtttttagag aggaggatgc tatgttagag ggcataaagg
    23941 catggatagt tagtgttttg ataggagcat ttatagtaaa tatagtagat atgattttac
    24001 caagttctaa gataaaacct tatgtcaacc tagttttaaa ctttatgttt gtatttattg
    24061 taataactcc agtagtagga tttttttcaa aagatatgag tttagaagat agaatattaa
    24121 aatctatggg aaactacaac aagcagtatg tagatagtac aaatgctttg gcaaaagaga
    24181 ctggaaataa tagtctatcc aagggatatg aggatgggtt aaaagaagta cttaaattaa
    24241 aacttgatga atatggttat gatttagaag atatagagct taatggggca aatataaata
    24301 atataaaaat aaaagaaaag aataatagtg caaaaagtaa taacagttcc aatgaagaaa
    24361 ataaaaataa tagtactaaa agagaggaag aaaacataaa ctctaatgac aaagaaaatt
    24421 ctaaacaagt cttcaaaaaa ggtacagagt atgggttgaa cctaaatgaa gaaaaattaa
    24481 aaaacgactt aataaaggtg ctggatgttt ctatagaaga tatacaaatt gataaatagg
    24541 agttgggaga atgttgaaaa acttaaatga caaagataag agaaaggtat attcactaat
    24601 aactatagca ggaatatgtg tggtttcatt agtattatta tcttgttttc ctagtagcaa
    24661 aagcgataaa caagttggaa aaacagagac taataaaaat gctgaaaagc aagtcactaa
    24721 agaacaagaa aaagatgatt tagagtcaaa attaacagca atactatcta aaattgatgg
    24781 tgcaggagac gttgatgtaa tggttacatt tgaatcaagt gaagaaatac aacctgcttt
    24841 taattcaaat aatacaacag aaacaacaga ggaaaaagat gcacaaggtg gagaaagaac
    24901 agttacgact tctagtgaaa ataaaacaat gataacttca aattcaagtg accctgtagt
    24961 tataaaaact acagagccaa agataaaggg agtgatagtg gtagcaagtg gagcaagtga
    25021 cccaagtgtt aaagagacac tttatagtgc agtacaaaca tcattacaag tagctggtca
    25081 tcaagtagaa atatattcta aataaataca tataaccggg gggataaatg aatgaagttt
    25141 aattataagg gaagaggatt tgtaataata actttaactg caatgttagt ggtagtagga
    25201 acagtgaatt atcaactaag taagaaatct ttattagaaa catcaaaaga gtttaaggca
    25261 tatgaagaag cacagttgca aaaaaatact gatgagagtg atagtagtaa gacagaggat
    25321 tctagtaatg tagataaaca agatggtaag gaaagtgctg atattgatat agttgatagc
    25381 aaagctagta aagtaaaaga aaaggcaact gagacaagta aggaaataaa agctcaatta
    25441 tcatcagaga aaaatatgaa aaaggcatct tatattttag atatgaaaat gaatagagaa
    25501 aaacaaagaa atgagttagt tcaagattta aatgaaatga taaataatcc atctacaaca
    25561 gaagaatcta gaaaagaagc ttctaatatg aaattaaata tagttaaaat tcaagaaaaa
    25621 gaacttcaaa tagaaaacct tttgagtaca aaagggtatg aagaagcgtt agtttatata
    25681 agcgataaca aagttaatgt agttgtaaat gaagctaaat tagaaaagaa agatgcagca
    25741 aaaatatttg atttagttgc agaacaagcc aatgtgaagt atgaaaatat taaacttaca
    25801 aataataata gtaataagta aagtataaac ctcagaatta actgaggtta ttttcttgca
    25861 aagtagactt gtatttggta ttattatact tataaaaata gttccttaaa atcaggaggt
    25921 aagttttaat atggaagata ataaatttgg acaagtaaaa atatctaatg atgtaatagc
    25981 tacaatagct ggtttagcag cattagaagt tgaaggcata gaaactacag caacattaac
    26041 agataagttg ttaaaaaata atggagtaaa aatacaaatc gaagaagagg atgttaattt
    26101 agatgtaatg gttacgataa agtatggaat gtcaatacca gatacagctt ttaaagttca
    26161 agaaaatgta aaaaatactg ttgagacaat gacaggactg aaggtttctc aagtaaatat
    26221 acacattcaa ggaatcagct ttaagaagga taaagttgat aaagaagaag caaaagcaac
    26281 taagaaaaat taatattagc cctctgaaaa gtcagagggt tttttgctgg taattgattt
    26341 tatatggata attaaactta aaggagaatt ttgattgatg aaaaaagata gggcacaaaa
    26401 gagtacaaca agagaatata taatgaaact tatataccaa ataaatatta ataaagaaga
    26461 ttttgaaact ttagaagata aagtagataa ttttttaaaa gataattcag aacatattat
    26521 aaatagatat aaagaacttg cacttcaata ctcaaaaaat acaaatttaa agttagaaga
    26581 tactgaaatt gaagatgtta tagacaaaaa atatataaat acagtatgca aagcattgaa
    26641 agaaaatcat gacaaaatag atgagttaat aaataagcat gctaaaaact ggacagtaga
    26701 tagaatgcca aaggtagatg tttctatact tagattgtct gtgtgtgaaa tactttattt
    26761 agacactcct aataaagtat caataaatga agcagtagaa cttgcaaaaa tatattgtga
    26821 tgataagtct cctaaattta taaatggtat attgggaagt gttgttgatg aaattgggaa
    26881 ataatataat aattggaatt gatactagct gctatactac ttctatagca gctatctctt
    26941 tagataagaa agttatattc aatgaaaaaa taatgttaga agtaagggat aattcaaaag
    27001 gtttaaggca aagtgaagct gtatttcaac atatcaataa tttagggatt cttagtgata
    27061 ggataaaatc ttttaaagat aagtttaatg tagaaggagt ttgctcatca aaaaaaccga
    27121 gacctgttga aaactcatat atgcctgtat tcaatgtagg tcataatttt ggaaaattat
    27181 tgtctagtat atatggttgt aggttttatg agactactca tcaagagaat catattgaag
    27241 caagtttatt aaatagtaaa ttaaaaaata ataataaatt tatttctgtt catatgtctg
    27301 gtggtactac agagatactt ttaacaagca aacaagatag tcatcacaat gtatgtgata
    27361 ctaatttagg taaaattgcc aaaataagta ttaaaaaaga tgataaaagt aagttataca
    27421 ataattttgg atataatata gatataattg gaggaagtaa agatattagc tttggtcaac
    27481 ttatagatag agtaggaatt aagcttggat ataaatttcc ttcaggaaag tatttggatg
    27541 aaaatgcttt aaattgtaat cttaaaatag aaagtggtct gaaaacttct gtaagagatg
    27601 ggtatatgaa tttatcagga ttagaaaatc aggtaaataa gattataaat gataatggag
    27661 ataatactaa tcaaaaagaa tatatatcta aattggtatt agattcagta gttagaaata
    27721 tgtttaaatc tttagtgtat ttatgtgaaa cttataatgt aaatgaagta gtatttgctg
    27781 gtggagtttc tgcaagtaag tatattctta gagaattaag catgaagtta agaaaaaagc
    27841 atatagaagc ttattttaca gaaccacaat attcaactga taatgctgtc gggtgtgcta
    27901 taataggatt gaataacttt ttaggagaaa gagtatgaaa ctaagagctt tagatataag
    27961 tgaagcaaac tcatatatta aaagaatttt aataaacgac ccaatacttt ctaatcttaa
    28021 agttaaagga gaaatttcta attttaaggt tcatagtagt gggaatgtat atttatcact
    28081 taaagatgaa acatcaaagt taaactgtgt aatttttaaa agtaatttta atcgcaattt
    28141 aaaattagat aatggtgtaa aaattatagc taatggatat atatcagtct atgaaagaga
    28201 tggtgcgtat caattataca ttaatgaaat tgaaatagag ggaataggaa atttacacat
    28261 agagtttaat agattaaagg aaaaacttaa taaagaagga ttatttgacc ctaaatacaa
    28321 gatacctata cctaaaatgc caaactcaat tggcgttata acatctccaa caggtgctgt
    28381 tataagagat ataataaatg taataaaaag aagatatccg aaagttaata taaagcttta
    28441 tccagtaacg gttcaaggag ataaatcagc tgaagaaatc tgtgaagcaa ttagattttt
    28501 caatcatatg aagaatgttg atacacttat agttggtaga ggtgggggtt cgatagaaga
    28561 actttggtct tttaatgatg aaatggtagc aagagaggtt tttaattctc aaattccgat
    28621 aatatcagca gttgggcatg aaacggattt tactatttgt gactttgtgt ctgatatgag
    28681 agccccaacg ccatcagcag cagctgagat tgctactcca tcattggatg atataaacta
    28741 taaacttgga aacataaaaa gtaggatgag taagtctctt acaaatcaaa tagagctaga
    28801 ccaatatagg ttagaaacag tatttaataa gataaataac tatttagatt cgtacacaat
    28861 aaaagataaa gttatacaat tagacaaaat atatgataaa ataatttttg gaatagaaaa
    28921 taatttaaaa ttagaagatg aaaaattagt aaaaattgga gcattactcc ataatttaag
    28981 tccattagct actatggata gaggttatag tataactcaa aaaaatggaa aagtaataaa
    29041 tagtataaaa ggattaaaaa taaaggatag tatagatata gtattaaaag atggaaattt
    29101 agaatgtatg atagataaaa ttgaaaataa agagggatag tatgaattta acctacgaag
    29161 aagcttataa aagattagaa agtattttaa gtgaattaga atctaaaaat gctagcttgg
    29221 atgaatcttt aagcctatat gaagaaggta taagccttta taaacattgt aataagcttt
    29281 tagatgatgc taaattgaaa ataagtaaat ttaatcaatt gggaatagaa gaagacttta
    29341 aaatagagga ggaataaaat tggaatttaa acaatgtcta aaagaaaaag caagttttgt
    29401 agaaaaagta cttaaagaat atatgcctaa agaagaaggg tatcaaaaaa ctgttattga
    29461 agctatgaac tatagcttaa gtgctggagg taaaagatta agaccaatac ttacattgga
    29521 ggcttgtaaa atagttggag gtaatgaaga tgaagctatt ccttttgcta ttgcaattga
    29581 aatgatacat acatattcac taatacatga tgatttgcca gctcttgaca atgatgattt
    29641 aagaagggga agaccaacaa atcataaagt atatggagaa gctatgggga ttttagcagg
    29701 agatgctttg ttaaactatg cttttgaagt aatgcttgca ggctcaatca ataaagaaaa
    29761 tccagaaaag tatctaaaag ctataaatga aattgccaaa ggtgctggta tatatggaat
    29821 gataggtggt caagtagtag atgtagaaag cgaaaataaa caaattggaa aagaaaaatt
    29881 agattatata catatgaata aaactgctgc aatgatggta ggctgtatga gagcaggagc
    29941 tactataggt ggagcaaatt ctgaacaaat ggaagaaata actaaatatg caaaaaatat
    30001 cggattatca ttccagatag tagatgatat actagacata gtaggagatg aagctaagtt
    30061 aggtaaaaag gttggaagtg atatagaaaa tcataagtca acatacccat ctcttttagg
    30121 tttagataaa tctaaagaaa ttgcacataa tttgattgat gaagcaaaga aaagtataga
    30181 aaaattatct gatgatgtag attttttaaa gggattggct gaatatataa tagatagaga
    30241 atactaaaat atacagctaa aatcgaggag ggaaaaatgg attttttttc ggagattttt
    30301 aacaatgggg ctttgggaat aagtctgatt gcttgtttct tagcacaatt tataaaaata
    30361 tttactggta aggaaaaaag aattgagtta tcaagaatac ttatttcagg aggtatgcct
    30421 agttcccata gttcttttgt tacaagttta gctacagtgg taggtattga aaaagggttt
    30481 aattctactg attttgctat aattaccgtg cttgccttaa ttataatgta tgatgcagca
    30541 ggtgttagac gggctgttgg taaacaagct actatattaa atcaaatggt ggcagatata
    30601 cagcatggaa agcatataga gcagaagaaa ttaaaagaat taataggtca tacaccacta
    30661 gaagtttggt ttggagcttt acttggaata gtaacagctt taatattgat gtaaattgaa
    30721 aatttacaga ataaaggtga ggataatatg tataaatatt tagataaagt aaattctcca
    30781 aaggatataa aaaatatgag tatagaagaa atggatttac ttgcaaagga tataagaaag
    30841 ttcttagtaa aatctgtttc aaagacagga ggacacttag cttctaatct aggagtggtt
    30901 gagttaacat tagcacttca taaagtattt gatagcccta aagataagat tgtatgggat
    30961 gtagggcatc aatcttatgt tcataaaata gttactggaa gaaaagattg ttttgtatct
    31021 ttgagacagt ttaatggact aagtggtttt ccaaaggaga atgaaagtcc tcatgatatt
    31081 tttgatacag gacatagcag tacatctatt tctatagcta caggtattgc ctgtgctagg
    31141 gatataaaaa aagaaaacta tagtgttata tctgtgatag gagatggttc tataacagga
    31201 ggtatggcac ttgaagcttt aaatcaatta ggatatatag ataccaatat gatagtaatc
    31261 cttaatgata atgagatgtc catagataaa aatgttggag gaatgtctaa atatctgtca
    31321 agtattataa gaaactcaac agttgagaaa atgacagatg aagttgataa aattttaaat
    31381 gttacacaaa caggtgaaat tttatctaag actgcacata gatttaaaga taaactaatg
    31441 tatagctttt ctcctcagga ctgttcattt tttgattcat taggtataag atattatgga
    31501 cctatagatg gccataatac taaagaacta atagatatat tgagaaaagc taaacacaaa
    31561 aaagggcctg ttcttttaca tgtaattacg aaaaaaggaa aagggtacag atttgcagaa
    31621 gaacaacctg ataaatatca tggagtatca aagtttgata taaagacagg tgttacatct
    31681 gcaaaagtta agtctatgtc aattagtgtt ggagaaaaac ttgttgatat ggctaatagt
    31741 aatgaaaata tagtagcaat aacagctgca atgccatctg gtacagggtt aaacctgttt
    31801 gaaagtgcat atccaaaaag atattatgat gttggtatag ctgaacaaca tgcaacagga
    31861 tttgcagcag gtcttgcaaa aaatggtatg aaaccttact ttgctgtgta ctcatcattt
    31921 ttgcaaaggg catatgacca agttattcat gatgtatgca taacaaaaaa gccagttact
    31981 tttcttatag atagagctgg attagttgga aatgatggag aaactcatca tggtatgttt
    32041 gatttaagtt acttaaattc tattccaaat attgtagtaa tggctccaaa agacacaaga
    32101 gagatggagc ttatgatgga tttgtcatta aaattagatt gtccactagc aattagatac
    32161 ccaagaggaa gtagttatta cctagataag ggagagtatg gagagattgt actgggtaaa
    32221 tatgaggtat tagatgacgg tcaagataca gtcatacttt gtattggaag tatggtaaaa
    32281 catgctttag aggctaaaga aatattatca agagaaggaa taaatccgac aatagttaat
    32341 gctagattct taaagccaat tgatgaaggt atgttaaaag cattattaaa aaatcataaa
    32401 aatgtagtta ctatagagga taatattgta actggaggat ttggaagtag aataaataag
    32461 tttattatag ataatgaata taacgtaaat atacttaata tagcaatacc agaagaattt
    32521 gtaaaacatg gcaatataga tgaattatat gattttgtag gattatcgcc aaaaagtatt
    32581 gctgataaaa taaggaaatt agttattgag taaaaatcta atgtagatat tgtaaattaa
    32641 aatttatata aaatatagaa tttatcaatt agaataaata tcaagtgtgt tacttcaagc
    32701 tactttagtt atcattaaag tagcttttaa cagaaaggta attgtatgaa aaaaagaata
    32761 gatttattat tagtagaaca agggtacttt gaaagtagag aaagagccaa aaaagcaata
    32821 atggctggat tggtttttgt tgataatcaa aggtgtgata aggctggtac agaagtaaaa
    32881 gaagattgta gtatagaagt aaaaggaaat ccaataccat atgtcagtag aggtggttta
    32941 aagcttgaaa aagcaatgaa aaactttgat ttgactattg atggaaaggt atgtatggat
    33001 ataggggcat ccacaggtgg ttttacagat tgtatgctca aaaatggagc aataaaagta
    33061 ttttctatag atgttggtta tggtcaactt gcatggaaat tgagacaaga tgatagggtt
    33121 gtgtgtatgg aaagaaccaa tataagaaat gtgacaatag aagatacaaa gcagtttgct
    33181 gattttgcgt caattgatgt gtcttttata tcgttaaagt tagtacttcc aaaggcaaag
    33241 gagttagtac gtcatgatgg ggaagttgtc gctttaatta aacctcaatt tgaagcagga
    33301 agagaaaaag taggtaaaaa aggagtagtt agagaaaaat ctacacatat agaagttata
    33361 aaaatgattt ctgatttctc agtcgaaaat ggatttgaga ttttagggtt agatttttct
    33421 cctattaaag gtcctgaagg taatatagaa tatctaattc atttgagaaa tggaaatgaa
    33481 ggatatgaat ttgatggtga gacatacaat aacaaaatag tagaagttgt tgaagcttct
    33541 cataatttag acaaataggt taaaaggggg cttagatttg atcctcgaat tatatatgaa
    33601 aaattgtgcc ttagttgaag aactaaggtt gaatattgat aaaaacttaa atatacttac
    33661 aggtgaaact ggttcaggaa aatctataat aatagatgca cttggacttt gtttaggtga
    33721 taaatatgat aggtcttttt taagaaaagg aacagataag ggacttgttg aggctgtatt
    33781 tttttcagac aatagatatc ttaaaaaaat attagaagaa aatgatataa gtatggaaga
    33841 tgataattta ttggtaataa ctaggttgat atactcagat ggtaagagta ctgctagagt
    33901 aaatggaagg actgttaaag tgtctcttct taaagaaatt gcatctacac ttatagatat
    33961 acatggtcaa catcaaaatc aagctttgtt taataaagat actcatttaa aatttctaga
    34021 cctttttgga gaaaatgaat tggaagagtt taaaattgct tataaaaatg tgtaccataa
    34081 gtatagtgaa gtaaaaaaag ctttaaattg cttgacagaa aataaagatg agatgcaaat
    34141 tcaacgagaa atagatttat taagatttca aataaatgaa attgaagctg caaatctaaa
    34201 taagaatgaa tatgaagatt tattaaaaca aagagaagtt tatagaaata gtgaaaagat
    34261 atataataat ctaaattcga gttatagcaa gttacataat ggtgagtata atgttattga
    34321 cctaataggt cttgcatcta aggaacttaa tgacatatct aaatatgaca gtgttttaag
    34381 tgaatatagt gatactgtag aaagaatcat gtatgagtta caagacatat ctggtgagat
    34441 aagaaattac aaagataata tagactttga accttatgag ctagagcaga ttgagcttag
    34501 aatcgacgag attaataact taagaagaaa atatggagac agtatagatg atatatttga
    34561 gtattatgga aaaattaaag atagattaga tgaaatatta aacagagatg aaagagttga
    34621 acagttaaga agcaaactga tgaatataga agaagattta aaaataaaag ccagtaaatt
    34681 gactaaagca agaatagaag tagcaactac tttagaaaaa atacttcttg atgaattaaa
    34741 aagcttaaat atgaaaaatg taatgttcaa ggttaatttt gaaaaaggtc catttacttt
    34801 agatggagta gatgatattg aatttatgat atcttttaac ttaggagaag atattaagcc
    34861 tatatataaa gttgcatcag gtggtgagat gtccagattt atgttagcgt ttaaaaccat
    34921 attggctgat atagatgata ttgatacatt agtgtttgac gagatagata ctggaataag
    34981 tgggatagca gcacagatag ttggtgagaa attgagtgat atagcaaaga aaaaacagat
    35041 aatatgtata actcatttac ctcaaattgc tgcaaatgca gacactcatt attgtataga
    35101 gaaagatact tcaaataata ggacgtttac caatgttagt aagttaaatg aatctcaacg
    35161 aaaaaatgaa attgccagac ttatagcagg taacaatata acagaaaaaa ctattgaaca
    35221 tgcaagtgaa attattgagt tggctaaaaa atgttagtga aaaacaagca ttttaatagg
    35281 tgtaaagaat ttttatagaa atgctttaca tctatttttt atgatgaaat tattttaaaa
    35341 tatctagtgc ctatattgaa gaaaagtaga tttaaaaata gaagaaaatt tgtataaatt
    35401 tgtaactttg aaatttctaa atgcttaagt ataatattat ttattaaggt agtagtgagg
    35461 gggacataaa atgaataaaa aagatactat gcacttaatt tttacaattg taatttttat
    35521 tttattatgg tatattgtgg tagcagtaag tgagattaat aaaaatattg aaagttgtag
    35581 taataaatta gattatttgt cacaagagat tatgagtact aaatcggata ttagtaatac
    35641 tataaatgaa gaaatgtcaa aaagttatat aacaaagagt attgacttaa aagtaaaaaa
    35701 aatcgagaaa aaagagtgtg ttattgatgt agatgttcaa ttaagtaaac ttggaaaaaa
    35761 tggaaaagta ttttttatgt ataaagaaga tagtgataaa tggaatgaaa ctgagatgac
    35821 aaaacatgga gaattatcat atgcatgtga aattaagata aatacaggaa gtgaatatga
    35881 ctataaagta gttacaagtg gagctatatc tgaaagttct gatgtgcaaa aattgactaa
    35941 atctgattat atgcctgaac aacccatatt taattctggg ataagagata atagagaata
    36001 ctttattgaa atagtagaaa atagtaatct tttcaatcat gagagtgaaa agtcaaaaaa
    36061 taaagtttat gataatatta gattagaaaa agtagatatt attgtaaatg aaggaaaaaa
    36121 agacactata tacaaagcca aattagctga aggcttagat gatggcaaaa ctaataattc
    36181 aaatagaaat caagtgaatt atgaagtaag ttttcctaaa agggatattg atgacataat
    36241 ttatattaaa gctaaactta catacaataa tggagtagaa tatacaaagg atataactga
    36301 agatataact atgggattac aagatttaga aaaataaata catatttaaa taaatattca
    36361 aatagatttg ttcaataaaa tagagtataa ataaaactgt agtagtttta cttatactct
    36421 attaaaaaat tataatttta attccatata tctagcccct tcaattggat tataagtata
    36481 aggttctata tcataaaaac caaacttttc atataatcct tgtgcacttt tcatgcttgg
    36541 aagagtatct aatctcatgt gtgtatatcc aaatttttta gcttcttcaa tgatttcttc
    36601 caatagtatt tttcctattt ttaatcctct aaattgattt cttacatata atctttttaa
    36661 ttcacatatt ttaccttcaa gtttttttaa agcaacacaa cctgccaaat tttcatcaac
    36721 aaatgccaat atcaatgagc ctgaaggttt tttatatttt cctggaagtg tttttaattc
    36781 attattaaag tcttgaaaac ataagtctat atttagagaa tttgaatatt cagtaaatag
    36841 aagttttacg ttttcaaggt tttctaaatc tttttcttca acaaattgta aagttatatt
    36901 ttgagccatt ttatccgcca ttatataaac atgtttatat aatgacttca cctccttgat
    36961 atatgtatat ttttcttaat atcaattaga ttttaatacc attacttttt caccaccata
    37021 gtcaagctct ccattaaact caaatccaaa atctttataa agcttaatag ccattttatt
    37081 gtcttcgaat atactaagat atagttcatc acagttatat tcatttttaa gatgatttac
    37141 aagaaaatct aatgatgctt ttccatatcc tttaccttga tattttgaat caatcataaa
    37201 tctatcaagc caaactctat catcttctaa acgaccatac atagcaaatc ctattaaaga
    37261 attttcatca tatattccaa caggtaccca agctgttata aatttagatt cagcaataga
    37321 aagtgcattg ctttctatat aatctaactg acttttatct acagacaaac taactaaatc
    37381 atgccaatta tttatgtctg caattcttac atttaatttc aagatattac cgcccttcaa
    37441 actttttgtt acaatctaat actatcatat tatgtattaa aaatcactta ttaagatttt
    37501 aaataaactt tttaaatgaa taaattctca ggaaaaagga attataaata cataataata
    37561 cagcatagga gtagatggat atatgaacaa aataaataaa aatttcaaaa atatttggat
    37621 aatattagga gctgtatcga tttttaccat ggttataatt tttaataaaa attgtaatgt
    37681 taataaagag actcaaatag aagcttttac aattaagaat catgataaaa aatttgtata
    37741 tcctatggga aatataattg gagtaaaagc aaatacagat ggtgtattgg tcttaggata
    37801 tgaggaagag gatgtagact atattggagg catacaaatc ggtgataata tagtaaaaat
    37861 agataataaa aggataaaaa atagtcaaga tgtatcagag attttgaata agattaaaaa
    37921 aagtaaagtt gaagtgactt ttgagagaaa aaataagtat aaaacagaag taatagagac
    37981 taaaaaagaa aatggcaagt ataaacttgg attatgggta agagataaaa tatctggaat
    38041 tggaactatg actttttacg accctagtat ggaaaagttc aaagcaatcg gtcatgccat
    38101 aaaagattcg gatactaatg aactattaaa gataaagcaa ggatatatat ataagccaga
    38161 acaattaaaa atagtaaaag ctagtaatga aaaagtaggt aaaataaaag gagattttaa
    38221 tgacagcaat ttaatgggta atttctcaaa taattcagag ttaggtataa gtggtaatat
    38281 tacagaaaac cataataaag agtttaatgt agcaaataaa gaaaagcaat taatagaagt
    38341 tggaagaccg caagatgtaa aaataggaga tgcagtaatt ctttttgagg ataaaaacaa
    38401 aaatataaca agctatgata taaaaataga aagtatagta tatgataaag gaaattatag
    38461 agatatggta ataaaagtag tagatgacaa gttattggaa tacacaggag gtatcgtaca
    38521 ggggatgagt ggagctccaa taatacaaaa taataaaatt attggtgcaa taactcatgt
    38581 ttttagagat aatccgaaaa aaggatatgg tatttttata gatgaaatga taaaattgta
    38641 ggtgaggcat taaaaaattt tattatttta tcaattatct aggaggaata taattttgga
    38701 gtgtcgaata tgctttagag tagataatta ggaagcaatt gtgtaaaaag tttagttttc
    38761 tgtaataaga agatgttttt taatgggggg atttttagtg gaaaaaatca aaatagtttt
    38821 agcagatgac aataaggatt tttgtcaggt attaaaagag tatttgtcta atgaagatga
    38881 tatcgatata ttaggcatag ctaaggatgg aattgaagca ttagacttag taaaaaagac
    38941 acaaccagac ttattaatac tagatgtaat aatgccacat ctagatggat taggtgtaat
    39001 tgaaaaattg aatactatgg atatacctaa aatgccaaaa ataatagtac tatcagcagt
    39061 aggtcaagat aagataactc aaagcgcaat aaatctagga gcagattact acatagtaaa
    39121 gccatttgat tttgttgtgt ttataaacag aattagagag ctagtttcta atagagttac
    39181 acaagttgag ccaaaaccta gaccagttca agagactcaa atgactagaa gtgattttgt
    39241 taagaatgta ggaaatatag agacagaaat cacaaatata atacatgaaa taggagtacc
    39301 agctcatata aaaggatatt tatatttaag agaagcaata aaaatggtta ttgataatgt
    39361 tgagctttta ggtgcagtaa caaaagagtt atatccaagt atagctaaaa aattcaatac
    39421 aacaccaagt agagttgaaa gagcaataag acatgcaata gaggttgcat ggagtagagg
    39481 aaaagttgac acaataaatc aattatttgg atatacggta cacaatacta aaggaaaacc
    39541 aactaattca gaatttatag caatgattgc tgataaatta agattagaac atagtatggt
    39601 taaataaaca agacataaaa agtaaggctt tttaattaag gcattggcta taaatgcgta
    39661 ttacaagcag cgaaacggta taaccactag ggttataccg tttcgctatt ttaataaata
    39721 taaaaatttt ctttattatt tgcttactat atcaatataa taattttatt atactatgga
    39781 tatagtatgt gtctttacaa gttgtaaact gacagtggtt tattttttaa tataaatatt
    39841 gactttgatg caggtaaact ttgtattttt aagcgtatta tggaatatgt taaataaaaa
    39901 aatgatgaaa tatagtattg taaatgccaa agatgcaaaa caaacttaaa acatttattt
    39961 tattgttaag taatgctata atataatgtg attttaataa tgatagtgga ggtttaaata
    40021 tgagagtcga ggcccctata aaagtagatc gaaaaaccaa aaaacttgct aaaagagttg
    40081 aaagtgggga aatagcagtt ataaatcata tagacataga tgaagttgct gcaaactctt
    40141 tagtagaagc taaaataaaa cttgtcataa atgcggctcc ttctataagt ggtaggtatc
    40201 ccaataaagg tccagggata ttaactgaaa ataatatact aataattgat aatgttggag
    40261 aagagttatt tgaagaatta aaagaaggag aaactataga agttgtagat ggaaagatat
    40321 atagaaaagg aaaattttta ggtgcaggag aagttttaga caagtatgag gtttcacacc
    40381 aaataaaggc tgcctatgag aatttagctg tagaattgga tagatttata gataatacta
    40441 tagattatgc taaaaaagaa aaaggattta tacttggaga agtagaaatt ccaaaagtga
    40501 aaactaatta tgctaataaa catgtattga tagttgtaag aggtcaggac tacaaagaag
    40561 atttaagtac tatgctttct tatatagaag aggtaaagcc agtattggtt ggtgttgatg
    40621 gaggagcaga cgctttaatt gagtttggat atactccaga tgtgattgta ggtgatatgg
    40681 atagtgtaag tgatgaagct ttaaaaaagg ctagtgaaat agtagtacat gcttatacag
    40741 atggaagagc accaggtctt aagagggttg aggaattagg cttagatgca gttgtatttc
    40801 ctgcgccagg aactagtgaa gatatagcta tgcttatagc ctatgagtat aaggctgagt
    40861 taatagtagc agttggtaca cattcaaata tgattgattt tcttgaaaaa ggaagaaaag
    40921 gtatggcaag tactttttta gttagactaa aaataggttc aaagcttata gatgctaaag
    40981 gcgttaattt gttatacaga agtaaattaa aaataaagta catatgggca ttaatagcaa
    41041 cagcattatt tcctgtgttg gtagttgcat cattgtcacc aggagttcaa cagttcatac
    41101 aactaatgca attaaagttt agagtattat tacagatgta aattttagga ggataaatat
    41161 gcatattaat atgaaatatt atatagtcac tataggggct atatttatag ctttgggtat
    41221 aggcatgtta gtaggattta atttaaataa taatcaacaa ttaagtgaac aacaagcaaa
    41281 tataataaat gatttggatg ataagtttaa tatcttaaaa gaaaaaaatg ataaacttga
    41341 cagtgactta gcaagtgtaa atagagatta tgaagaggca gttaatttta taaataaaaa
    41401 tgtagataag attttagctg gttcgctgaa tggtaagagt ataggaataa tatctgctaa
    41461 tgaaaatgac gattatacaa aaaatataga agacataata aataaatcta atggaagcat
    41521 tgcatttaat ataatattaa aagaaaacat aacaaatcca gaaaagttaa aggaaatgtc
    41581 aactaaacta ggtacagatg taaaaaatgc aaatgatgca gttaattata taattgacac
    41641 tcttaaaaag gaagatgcaa gtgacatttt aacatatctt caagaactag atgtaataaa
    41701 gtttaatttt attggagata catatctaaa atatgattcc gttgtaatag ctggtggaaa
    41761 tgatgcaaaa gacagtacaa aacagtttga aaaaatagaa aaatttgtag tttcaaaact
    41821 taaatcagag aataaatatt tagtagaagt tcaaaataca ggagttaaaa cttcttatgt
    41881 agaactatat tctaaaaaca aagttgcaac tatagacaat attgatgaag gtataggaag
    41941 tatatctcta gcgattcttc tacaacaagg taatatagtt ggtaattttg gtagattgga
    42001 tactgcaact tcattgttgc catctattaa atagaaataa ttttaaggag agaaaaaatg
    42061 gattcttata taagtataat aataccagct tataatgaag aaagtagaat aaaatataca
    42121 ttagaaagca tattggacat taagcaaata aatgaaataa tagttgtgga tgatggttca
    42181 attgacaata ctgctaaggt tgtatctgag ctagaaaatg aaaagattaa attttttaag
    42241 ttagataaaa atagaggtaa aggatatgct ttaaattatg gtatcaagtt agcaatgaaa
    42301 aatgcagata ttataggttt tctggatgga gatttaggaa gttctgctaa agaagttgaa
    42361 aaattaatag tacctatatt aaatggtgag gcggatgtta caatagccaa gtttcctcct
    42421 gcaaagagaa aaggaggttt gggatttgta aaaggtttag ctaaaaattc tgtgtttgag
    42481 atgactggtg ttgagttaga tgcaacttta tcaggtcaaa gaatatttaa aagagaagtt
    42541 ttagaaaagt ttgatgaaat accttttgga tatggagtag aagttggaat gaccattgat
    42601 atattaaagt atggatttaa aattaaagaa gtattagtaa atatgactca taatgaaaca
    42661 ggaagaaatt taaaaggttt tattcataga gggaaacagt attatcacat aaaaaaggtt
    42721 ttaggacaaa aaaagaaaga atggaggtaa tatcttagtg aaagattata tactttatac
    42781 cattttatta ttaactggat tatttggaac ctatgctgta attccactat ttaaaaattt
    42841 attgataaat ggaaatgtac ttagaccaaa ctataaaaaa gatatgatac cagtaagtat
    42901 gggaattgta tttttgccta tgattgtaat caatggaata atacttgctt tctttactac
    42961 agaatttaag aatttagcgt atatatttat gtttatgttt ggtatgatat ccatgttttt
    43021 tgcagggata ctagatgatg tcattggaaa tagagatgta agtggtttaa aggggcattt
    43081 taaaagttta tttaaaggaa gtcttacaac aggaggtttt aaagctttat ttggtggatt
    43141 tgtagggctt atagtttctg ttgctatatc aaaagacata attgatataa tagtaaatac
    43201 actaataata gctctatcaa ctaatttaat gaatcttttg gatttaagac caggaagggc
    43261 aataaaagca tatttattca taatggtaat tgtattttta acattgacag gatttgttca
    43321 agttcttcca ttacttatag taccaaatgt acttgcatac tttaattatg atttaaaagc
    43381 aagggctatg atgggagata ctggttcaaa cgtccttgga atatctattg gaatgctcat
    43441 ttcttttggg tatccattta acattagatt aggatggtta atatttgtag ttattatgca
    43501 tatattcact gagaaatact cattaactaa gataatagaa aaaaataaac tattaaattt
    43561 tatagataaa ttgggaaggt agtattatga taagcaaaag agtggggatt gttgaatcaa
    43621 tagtaagtca aactgaaact ctagatgata taagagtaaa tataaatgga gaaatacaaa
    43681 aggcatataa ttatccaaaa atatctggaa ctataaatat aggtgacgaa gtggttttaa
    43741 atacaacagc agtagaactg agcttaggta caggtggata ccattttgta ataactaatt
    43801 taaataatat agaatctact ttaactgaag gtggacatat aatgaaactt agatatacgc
    43861 ctcttcaaat aaaagtggat tctgttgagg aacaagaaag tatttatcat gataaatttg
    43921 cgaattttaa aggattagaa ggtctttctg ttgtagtagg gactcttcat agtatgttaa
    43981 ctccatttgc agcttcattt aaaagaaata atccaaataa aaaattagtg tatataatga
    44041 ctgatggagc atctcttcca atttatttaa gtaaaaatgt ggatacttta aaagaaaaaa
    44101 aattaataga tagtacaata actataggaa atgcgtttgg tggagattat gaatgtataa
    44161 atatatatac tgcattaatt acagcaaaag aaatactaaa agcggatgca gtatttgtca
    44221 gtatgggacc tggaattgct gggacaggaa caaaatatgg atttacaggg attgaacaag
    44281 gctctattct tgatgctgta aaaaaacttg aaggaagagc aattgcaatt ccaagaatta
    44341 gttttgctga caaacgagaa agacatcaag gtatttcaca tcatagtatg actgtattta
    44401 aagaaattgt aaatgtaaat gtagacatac caataactat atatgatgat gaaaaattga
    44461 actttataaa agagcaaatc aatttaaatg gtttagacaa aaagcataat ataatttata
    44521 tagataataa taaaacgaaa gaggatttag actattttaa tctaaaagta aagagtatgg
    44581 gaagaaatta tgaacaagat gaggcatttt tcaaagctgc aagcacagca gcatattact
    44641 taatggaggt ttaagatggt attagaagaa aaaactatta gtagtgatag ggtttataca
    44701 ggtaaagtaa ttactttaaa ggttgatact gttgaaattc cagggcaagg atatcaaaaa
    44761 agggagttag tagaagttgg tggagcagta ggaatagttg caatcacaga tgataataaa
    44821 gttgtgttag ttaagcaatt tagaaaacct atagaaaagc caatctttga aattccagct
    44881 ggtaaactag aaaaaaatga aagtccaaaa gaatgtgctg aaagagaatt aaaagaagaa
    44941 actgggtata gtgcaaaaaa tattaagcta atacataaat ttttcacttc agcaggtttt
    45001 tctaatgaga taatgtttgt atatttagca acaggtctta ctccaggaga gaataattta
    45061 gatgcagatg agtttttaga tgtttatgaa attgagcttg aagaagcata taacatggta
    45121 ttaaaaaatg acgttgaaga tgcaaaaaca tctattggat tattattagt aaaagatatg
    45181 tttaaaaatt aatatttata aaatgaataa ccctttgtcc taaagcatat tattttataa
    45241 aggacaaggg ggaattaaat tgagaagaac atatagaaaa aatgatttta gagaattaaa
    45301 tagacaaata attattatag gattgttgtt tatgatgtct attgttgttg ggtcttacat
    45361 aaataaaata ttgccaggtt ctagtaacaa tatattaaac aatataaatc ctgctgtaga
    45421 gtattataat ctaaatataa gcataaaaga tacagtgata caaaatttaa aatcagatgc
    45481 aatctttatg ggctcaatag ctctattaag tctatttgta gtaacaattc cagcagtgtt
    45541 ggtagctttt gtattaaaag ggatgtcaat tggttataca ataaatagtt gtatattggc
    45601 attaaaattt aaaagtataa aaatgatttt aataatatta tttaaaaatt tgattattat
    45661 tccatgtgca atcatattag cattaattag tttaagttat tttaaagaaa tggtttatga
    45721 atttaaaaag aaaagtagaa aaaatatgca atttttaatt aagaggtata tactaaatat
    45781 tataattata atagcactat cattggggtt gcaattaata ttaaatactg caagtattgg
    45841 tattattaag ttcctagcta aataaaggag tttataatgg atattataga gggatatata
    45901 gattacataa aagataaaaa aaaattatca gagaatacag tggcatcata ctttatggat
    45961 ataaaaaaat atatggaata tataaatcaa aaaagcatta aactagtaga tatagtagaa
    46021 aatgatatta taagttactt aataaagttg gaaaaagata atgtatcaat agctacaata
    46081 gcgaggatga tatcctctat aaaatctttt catgattatt tatttttaaa tcatatatgt
    46141 acaaataatc ctgcaaagga tataaaaaaa cctaaaataa aaaaagaaaa tataaatata
    46201 cttacagaag aagaaattga aagactatta aattttccaa agttaacaac acctaagttg
    46261 attagggaca aggctatttt tgaagtatta tatggtactg gtataaaagt atctgaatta
    46321 gtagagatga atatagagga tattgaccta gatattgatt atatatattg taattcatgt
    46381 tgtaaaaatc aaagagtgat accactttgt gatattacaa aactttactt agaaaagtat
    46441 ctaaaagaag caagacctaa aatggctgca gaaggtgaaa aatcattatt cgtaagttca
    46501 ttaggtcaaa ggtttacacg acaaggtctt tggaaagtca taaaaaaata ttctaatcta
    46561 gccaatatag ataaaaatat aaatcctaca atgcttagac attcatttgc tattcatttg
    46621 ttaaatgaag gtgctaacat tgctgttgta agtaaaattt taggaaatgt taatttatct
    46681 agtttgcaag tatatttaaa tcatatagat aaaaacgtga gaagagaaat aaaggagaaa
    46741 catcctagaa atgatgttga tgtagaatta caaaaagcag aagctaaata gactatatag
    46801 caaattttat aatttagaag gagcatattt atatgagcag agtaatttgg attgtaattg
    46861 atagtgttgg gataggagca ttacctgatg ctgaaaaatt tggtgatagt aaggatgtaa
    46921 gtacccttgg aaatatattt aaggaatatc cagatattca gattcctaat atgagaaatt
    46981 taggtatagg aaacatagaa ggtatagatt tttttgaaag tataaaagaa ccaataggtt
    47041 gttttggaaa gtgtaaggaa atgtctcagg gaaaagatac tactacaggt cattgggaaa
    47101 tgactggtat aatagttgac aaaccattta agacatttga acatggattc tctaaggaga
    47161 taatagaaga gtttgagaaa aaaactggaa gaaaagtagt aggaaataaa ccagcttcag
    47221 gaactgtaat aatagatgag tatggagagc atcaaataaa aactggagat gtaatagtgt
    47281 atacatcagc tgatagtgta tttcagattg ctgctaatga agaagtaatt cccctagaag
    47341 aactctataa tatgtgcaaa atcgctaggg aaataatgat gggggataat gcagtagcta
    47401 gagtaattgc tagaccattc ataggtaaga aaaaaggtga gtttgtgagg acttcaaata
    47461 gaagagatta ttcactagac ccatttgaac caacagttct tgataatata aaagaatcag
    47521 gacttgatgt tttagcagtt ggaaaaatag aagatatttt taatggaaaa ggaattacag
    47581 atgctatcca cactaaaagc aatatggatg gagtggatga aactttaaat tatatgaaac
    47641 aagataataa aggtctaata tattcaaatc tcgttgattt tgattctaaa tatggtcata
    47701 ggagagaccc agaaggatat aagaaagctc ttgaagagtt tgatagtaga cttcctgaaa
    47761 taatggctaa tatgagagaa gatgatattt taataatcaa tgcagaccat ggaaatgacc
    47821 caacatataa aggtacagac catacaagag aatatatacc tgttatgatt tatggcaata
    47881 agattaaaaa aggttttaat ttaggagtaa aagatacttt tgctgatatt ggagcaactg
    47941 ttgcagatat actaaatgta aagttgccta aacatgggtc aagctttaaa gaagatttat
    48001 tttaaactat aaaatgataa aaacttagct taataggatg gagagattgg aatgtttgaa
    48061 aagatagcac aaagtagtaa atttataaat tctaaaagta atataaaacc taagattggt
    48121 ttgatattag gttctggact aggtgattta gcaaatgata tagaagaccc tgtcacaatt
    48181 aaatatagtg aaattccaaa cttccctgta tcaacagtag caggacatgc tggacaactt
    48241 gtaattggaa aacttgaagg aaaagaagtt attgctatgc aaggtagatt tcattactat
    48301 gaaggatatt ctcagaaaga agctactttt ccagtaaggg ttatgaaaga attaggagtc
    48361 gagattctta tagtaactaa cgctgctgga ggcgtaaata aagaatttaa agcaggagat
    48421 ttgatgctta taagagacca tataaacttt agtggaagta atccattagt aggaaaaaat
    48481 gatgacagat ttggtgctag atttccagat atgtcagatg catattcttc taaatatgta
    48541 gatgtagtta aaaactgcgc taaagaatgc aatatagatg tcaaagaagg cgtttatatg
    48601 ttttttagtg gtccaaacta tgaaacacca gcagaagtga gaatggcaca aattttggga
    48661 gctgatgctg taggtatgtc tactgttcca gaagtcatag tagcttctca ctctaatata
    48721 ggagttattg gtatatcttg tataacaaat atggctgctg gcatcttaaa tcaaccacta
    48781 agtcatgagg aagtaataga aactactcaa aaagttaaat cagaatttat gaatttagtt
    48841 aaaacaacgg ttaaaaattt ataagttaaa gcttattata gattttttga ggaagtttat
    48901 aataaaatag ttaatgttta atttgaaaag aattaataaa aagctgtctt gatatagaaa
    48961 gttatttcta ataaaggaca gtttttttat aatactacaa catttgaaag tgttttaaag
    49021 tttaatattt atttaaatta ttataggtta gaatggagat ttcaattatg agaatgtatg
    49081 atattataaa aaaaaagaga gataacctag agcttagtaa aaaagagata aactacttta
    49141 tagaaaacta ttcaaaggga gatatacctg actatcaagc ttctgcacta ttaatgtcga
    49201 tttatttaaa taagatgaat aaacaggaaa ctgtacatct tacagaagca atgatgaact
    49261 ctggagacat gataaaccta tctgagatag atggaataaa ggtagataag catagtactg
    49321 gtggtgttgg agataagact accatagctc ttataccttt ggttgcttca tgtggagcac
    49381 cagttgcaaa gatgtcaggt agaggtcttg gtcatactgg tggtactatt gataaattgg
    49441 agtctatacc aggtttttcg acagaaatgg agataagtaa atttattgat tctgtaaata
    49501 agtctaaaat agcagtttgt ggtcaaagtg caaaggtagc aattgcagat aagaaaatat
    49561 atgctcttag agatgttaca gcaactgttg ataatatatc attgatatca tcaagtgtaa
    49621 tgtctaaaaa gttagcttca ggagctgatg caattgtgct agatgtaaaa actggtgatg
    49681 gagcatttat gaagacatta gaagagtctt ttgagttagc taaatctatg gttgatatag
    49741 gtactggtat gaatagagat acaataggga ttgtaacaga tatggatgaa cctttaggtt
    49801 ttgcagtggg aaactcttta gaagttatag aggcaattga gacattaaaa ggaaatggac
    49861 ctaaagacct tgttgagcta tgcgaagtat taggagcata tatgttggtt ttatcaaagg
    49921 tagcacatga ttttgaagat ggtgttgaaa aaataagaga atcaataaaa tctggtactg
    49981 ctatacaaaa actcaaagag tttatagaga atcaaggtgg taataaagat gtagtagatg
    50041 attattcttt attcaaaaaa tcaaagtata aatatccagt taaatcaact aaatcaggtt
    50101 atataagcaa aattaaagct gaagatgttg gtgtatcggc tatgattctt ggagcaggta
    50161 gagaaactaa agatgatatt ttagatttat cagcagggat aattttagaa aagaaagtag
    50221 gagattatgt aaatgaaggt gaagttttag cttacatgta ttataatgat gaacaaaagc
    50281 tttcattggc aaagggaaga tttattgatt cctactctat tgtagattca aaaatagaaa
    50341 aaaataaatt aatatatggt attgtaacta aagaagagat taaaaagttt tagaaaattt
    50401 tagaaaagtg attataaaag gcctaacatg tcaaaaataa tgttaggttt tttatttttt
    50461 gataaactat aaattatacc aaaaatatat attttaaaac attttttaca atataaataa
    50521 gtttattcta caagatgatt gaaaattaaa gtatctagtt ttataataga aaatggataa
    50581 atatacataa ggagtagatt atattatgaa ctttaaagaa aatagattga aaatagcagt
    50641 attaataatt gttattttga ttatcttagc aggtatattt gtgtttatac aaataggtcc
    50701 ttatgataaa aataacaaaa aagatgtaat tatcgacgtt ccaagtggag catctgttgg
    50761 aaaaatatct gacatattat atgaaaataa attaataaag aatgaactat tatttaaact
    50821 tttggtaaag gttagcaata aagctccgtc tataaaatca ggaacatact tacttaatca
    50881 atcgtattca aacaatgata taataagtct tttagtttca ggtaaaatat atcaggatgg
    50941 tataaaagtg actattccag agggagctac atctaaagaa attatagcaa tgttagtaag
    51001 taaaaattta ggagataaag ctacttttga aaatttaata aaaaaacctc aagaatttta
    51061 tgataaattt tcatatttga aggaagatgg aataacctct ttagaagggt tcttgtatcc
    51121 agaaacttat tattttaatt caaagaaaca atcagaagaa gatattttaa gcgaaatgtt
    51181 aaaagtattt gacagtaaat acacggacaa gtttaaaaag aaacaaaaag aattaaatat
    51241 gactcttcaa gaagtaatgg aaatggcatc aataattgag aaagaagctg ttcttgacaa
    51301 agacagacct ataatagcaa gtgtgtttta taatagactt aaggtaggta tgcctcttca
    51361 atcagatgct acaatacaat atatatttga agagagaaag aaaattgtaa catatgatga
    51421 tttaaaaatt gattcaccat ataatagtta taaaaataag ggattacctc ctacaccaat
    51481 atcaaatcct ggtataaaat ctattgaagc agcattatat ccagagaaaa cagactattt
    51541 atattttgta gctaagattg atggtggaaa taattatagt acaaactatc aagaccattt
    51601 aaaatacgtt aaagaatata aagaagcaag ggataaacaa tcaaaagata caaaagcaac
    51661 aaataaagaa aatacaaaaa aataaaccat gattataaaa agtctaacag ggtaagaata
    51721 atgttgggct tttttattga aaattgttat tcttagattt ataataaaga aagtgtaaat
    51781 atatataaca atatgaattt aaaaaataat aaattaatat aaaacttgga tatttattat
    51841 tttagggagt gtttttatga gtaatatagt taatgatttg gttgaagatt atataagagt
    51901 gacattaaaa gaaaaagaag gatttttaaa agatttagaa atttatgcag aggaaaatag
    51961 tgttcctata atacataaag aagtttcaga tttattaaaa gtcttgttaa aggttcaaaa
    52021 accaaagaga attttagaag taggatgtgc aattggttat tcttctattt tttttgcaac
    52081 tattatagga aaagatgcag atataataac tgttgagaga aatgaaaaaa tgatagaaaa
    52141 agcaaaagaa aacataaaat tagctggatt tgacaataac ataactatac tagaaggaga
    52201 tgcagaagaa aaacttagtc aagtccaagg tgaatttgac cttatattta tagatgcagc
    52261 caaaggtcaa tataagctat tttttgattt agttatagat aaattaaaag atgggggact
    52321 tttagtatct gacaatattt tgtataaagg tatggttgct catgatgatt ttgttgtaag
    52381 aagaaaaaag actatagtta aaagaatgag aaagtattta gattatatat gtaattgtga
    52441 ctatttaagc acatcattgg taccaatagg tgatggtgta gcactaagtt ataaagaaag
    52501 taaaagaggt gatgtagatg gaattaaata aagtagaact tttagctcca gcaggtgatt
    52561 tggagagatt gaaaatagct ataacatatg gagcagatgc cgtttatata ggtggagaaa
    52621 tttttggaat gaggtctgca gcgaagaatt ttagtaagga agatatggca gagggagtag
    52681 cttttgcaca tgaaagaggc aagaaagtat tcgtaacagt aaatataata cctcataatg
    52741 aagattttct acaattagaa gactatttgt tggaactaga agagatagga atagatgcag
    52801 ttataatagc tgacccagga gtgcttagtg tcattaaaaa agtaattccg aatatggaaa
    52861 tacatttaag tacacaagca aatacaacca attatctaag tgcaaacttc tggtacgagc
    52921 atggaataaa aagagttgta gtggcaagag aattatcttt tgatgaaata tatgagataa
    52981 gagcaaaaac acctttagat atggatatag aagcgtttat gcatggtgct atgtgtattt
    53041 cttattctgg cagatgttta ataagcaact atatgactgg aagagatgca aacaaaggtt
    53101 cttgtgctca atcttgtaga tggcaatatc atttggtgga agaaaaaaga cctggtgagt
    53161 attttccaat atacgaagat gaaaggggta cattcttctt taactcaaaa gatttatgta
    53221 tgatagagta tataccagag ttaatcaaat ctggtataac aagtttaaaa atagaaggta
    53281 gaatgaagac tgcatactat gtagctactg ttgtaagagc atacagaatg gcaatagatg
    53341 aattttacag agacccagaa aactggaagt ttaatccaat gtggatggaa gaactaaaaa
    53401 aaggtagtca tagacatttt acatcaggtt tttacttgaa taaaccaaca acagaagacc
    53461 aaaattatca atcagcatca tatgttagaa actatgattt tataggtata gttagagaaa
    53521 cagaagatga agatggtctt attgttgttg agcaaagaaa taaaatgtgt gttggtgatg
    53581 aaatagaagt tatgggacca tataaagaaa ctatgtttac taaaattgaa gaaatgtata
    53641 atgaagaagg agaagctata gaatcagctc ctcatcctag acaaatagtg aagttaaagc
    53701 tatcagtaaa agttggtaaa gattatatgc ttagaaaagt tatagaagaa aaggttgaag
    53761 aataataaaa aattgataaa aatagtatta gccccttaga aattgtcaat aatgaaatta
    53821 tctaaggggt gatttcatgt caaaaaagaa gactccattt ttgaaaaaag tgggaaagag
    53881 aagctggtgt atatttacta taattttaat aatttatagt gttttaattt ataggctagt
    53941 tgatatacaa gtattaaaag gtgataaata caaacaaagt gttgaatcac aaagcgttga
    54001 gaaagtcgag ttaaatagtg gaagaggaat aatctatgat agaaacaaca agaagcttac
    54061 agatacaagt aaatctcagg tattaattgt tgaaaaagaa aaattaaata ataactataa
    54121 aattttggag cttattaaga aagctactaa gatgaatgat ttagatatat ataaagctgt
    54181 acaagagcaa ttgacacgcc ctataataca gattcagact aaaaatatcg atatcgataa
    54241 gagtatgaaa aaagaacttg agaaaaatgg aataatggta gaagaaaaaa ctatgaggta
    54301 cgcaaaagat ggtttattat cacatacaat aggatatata aaagaagatg ataaatcagg
    54361 tcaatcagga attgaaaaga gtatggatag tgtacttaga aattcaaatg aaaagtatat
    54421 aagtgctttt aaagctggag atgcaggaaa tgaaaaatct ctaaacatac taaagggaag
    54481 tgtaaaaact gttgataata aggataaaga tagacatcta aaaactacta ttgattataa
    54541 cattcaaaaa aaattagaac aaatactaaa taaagaagaa aatcctacag cagcaataat
    54601 ctcggaagca tctacaggtg aaattcttgc aatgtgctct agacctaatt ttgaccaaaa
    54661 tgacatatca aaaagtttaa aaggaaaaaa tggagaattt gaaaatagag ttataaaagc
    54721 gacatatcca ccagggtctg tatttaagat ggtagtttta ttttctgcac ttgaaaatgg
    54781 tgttatagat gagaactata cttacaactg tacaggtaag actaaagttg ggaatactaa
    54841 tgaaatactg cgatgtaata aaagagatgg tcatggtttc caaaacttaa gacaagcttt
    54901 ttctaattca tgcaatcctg catttttaga tatagctatg aaacttggaa aagaaaagat
    54961 actcaaatct gctgaaaaat tacatttatt tgaaaaggtt gatattggtc ttgatgaaga
    55021 aaaaattaga gaagctccaa aaaacatatc aataagaaat ttagctatag gtcaagaaaa
    55081 tatagaattt acaccacttc aaataaatca aatgactcaa ataatagcta ataatggaac
    55141 attcaaacca ctatacttat ataaaagtct tgtggacaat aatatgaata caataaaaac
    55201 ttataagtct tcaaaaaaag aagaacttat ttctccttat gtgtgtacac aagttaaaga
    55261 atatatgaag tctgtatcta ggactggtac agctaaagac ctaaaagata ttgaaggtgg
    55321 ttgtggagtt aaaactggta cagctcaaag tagtttaaat aaaaaagcta tagaccacgg
    55381 atggataaca ggattttatc ctgaagaaag acctaagtat gtaataactg tgttagtaga
    55441 aggaactcaa aaaggaaata aatctgcaac acctatattt aaggaaatat gtgaaagtat
    55501 aaaataaatt atgtactata aaatttaagg atatatcgta actttgattt tagatagaaa
    55561 attttgtcta atgatgtacg atatatcctt ttaaaatata gtattaactt tcttgaacaa
    55621 gctctttttc tagtttttta agagcttttt tttcgattct agatacatat gaccttgata
    55681 tatcgagttt ttgtgcaatt tctctttgtg tcttatagcc ataaggagtt aacccatatc
    55741 ttaactggac aatttctctt tctctaggag taagaatttt gtttagttgt tcgtaaagtt
    55801 ttccaacttg aacttttagt tcaacttcat caagaacata gttagcctct gtaccaagta
    55861 tatctaaaag acttatttca ttacacacta ctctttatat gttattggta ttactggtct
    55921 tcatgtaatt tcaaatggac cattaattca aaagaatcta gtttttgttc tttagactta
    55981 taataaactg ctttatcaat tacagatttt aggagtttat tttttccaag ggaatctgaa
    56041 tcatggtaaa gtgataacac agttttaata tcttctatta ttttagaatt gtctttttta
    56101 acagtactca atctattttt tactgtctta attgaatctt taatttcttc agttcttgaa
    56161 cttatattgt tggacctttc aataaatgta tcttcatcat atattcctcg ttctagtaaa
    56221 tcatataact tatttttttg cttgcctaat tcttttaatt cagtttctaa gccctttaag
    56281 actcgttttt gaaattctat attactatct ttattatttt tatctaagtc tatatcagat
    56341 gcttttaatt gatatttttt tacagtgtct tccaaagatt ttaaaatggc agcttcaata
    56401 aattcaaatc gagaactttt attgcaacca ggatgataac aaattatata gtcgtggtct
    56461 gcatatggtc tatatactaa tggtctacca caatttttgc aaatcactat tcctgcaagt
    56521 ggatttttta tttgattacc atagctgaca tgaccatttt ttttgagtat attttgagct
    56581 tttttccatg ttatttcact tattaaaggt tcatgctttc cttttgcctc aatccattca
    56641 tctttaggtc ttagtttaac tgtttttatt ttatttggat ttttagattt tttgtagtcc
    56701 tttttttgcc actgaatgta gccacaatat gccttatttt ttattatatt tgtaattgca
    56761 gaattgtacc aattagcacc tgtagcagtt ttaatgccta agttatttag gtattttgat
    56821 attttactac aacccatatc ttcattaata tataagtcaa agatagtcct aactacatca
    56881 gcatctttat ttggtacaag tattctttct tttctaccag ttgttacagc atcatatcca
    56941 aatggagcag aggttcctat gaaattccct tcttcaactg attttattct acctctttgc
    57001 atccttcttg atataagttt taattctttt cttgccataa atgcttcaaa ttctgaatac
    57061 tcctcatcaa attcatctgt taggtcgtat gtttttctag gtgtgatgat tttggtctta
    57121 ctttctttga atgtttctaa tatgatacct tggtctttca tgtctccacg accaagtctg
    57181 tctaagtcca ttactaagac tgcatcatat ttattttctt caacttcttt tagaagttca
    57241 agcattttgg gtctatgtat tatactttca ccagaaacta attcttcttt tatctcaatt
    57301 acatctaagt tttgttcttt tgctagtttt agtagggttg atttatgtct acttaaagtt
    57361 tcaaattcgc cttgtttttc tgcctcttca tcagcacggg attttcttaa gtatatggca
    57421 acactcataa taagtaatca cactccttat gcactattat atagtaaatc aatagagttt
    57481 aaaatataga aaataagcat gtcaaaagtt aatttaactt ttgacatact tattttctat
    57541 aatattaatg ccttataatc ctttaatatc atttagatta gtttttgcat attcattatc
    57601 cgggttaagt tcaagcgcct tattgtaaga ttctctagct ttattaaatt ctgatttact
    57661 cataaaaata acacctctta aattgtaagc atcactagcg tctattttat aagcttcatt
    57721 atttttatct agatattcta agtatttatc aattgacttt aaagcctcat catatcgttg
    57781 taactctata taaatatatg attgtgtata atatgcaagt ggatttttat catcaatttc
    57841 tatagctttt ttgatatcaa tagcagcttt attataatcc ttatcttcat ctttttctgt
    57901 ttctgaccta gcgattttga cataattaga gctaagagct cttttaaagt ctttatgcca
    57961 taataattta tattcattat cttcgattat aaaatatcta tcaaaatttg cagtatcttc
    58021 tttattttca gtgatatact ttatagtatc agtttctttt attttaacaa gatttgtgta
    58081 ctctttatta gaatatttgt atttctctac tttattttct tcaccaagtt tataatcttt
    58141 tagggtttga agtttaaata aagtatcttg atattcttca aatttttcta gactgacact
    58201 ttccttactg tctttactta ataaattata tgctacttcg tagtctttga tttctatact
    58261 atcaaggtac tttttagcta cttctgtagc actttctttt ggagcacatc caaccattga
    58321 tatcataatt aaaaatgata ctaatattgc tgttattttt ttactgatta tcataatata
    58381 atccccctta tattgtctct cattaatttt attttatcac catattctac caaagtcatt
    58441 aatttaagag tgatattttt cattaatatt atattaagta ataataacct tttaaattta
    58501 tggtaaaatt ttcctgaaaa gtattatata atttaggtga aaatatttaa gagaaggaga
    58561 tattatgaaa attaaaaaat tattaacaat agggttatct ttatctatat ttattgctag
    58621 ttgccctata tctgtaaatg ctcttgataa aattgaatca attaaaggtg cagataaata
    58681 cgaaactgct ggtataattg cagacaaaca aaactatact acagctatat taattaatgc
    58741 agacagtaca atggctgatg gattaagtgc aagtggactt gcaggagcta taaacgctcc
    58801 aattcttttg actaagaaaa ataacatacc aaatgctaca cttaaaagat tagaaaaggc
    58861 aaaaaaagta tatataattg gaggagaaaa ctctattgat aaatatactg aaactgttct
    58921 aaaaggcaaa ggaatagaga ttaaaagact tcaaggtagt gatagaatta agacaagcta
    58981 taatgtcgca aaagaaataa actcaattaa caaagtaaat aaagtcatat tgactaatgc
    59041 atttaaagga gagcctgatg caatgagtgc tgcacctgta gcagttagag ataaagcagc
    59101 tatagtatta actgatggaa aaagtgttcc atttaataca actggtgtag aaagttatgt
    59161 aataggtggt acttcatcaa tgaatgacaa aatagttaag gatactaatt caactagatt
    59221 aggtgggaca gatagatatg atactaacaa aaagataata aataaatttt atagtggagt
    59281 aaaagaattt tatatagcaa gtggtactga tttagtgtat gctcttgttg gttctactgt
    59341 tgctaaaaat aatgctattg tgttagttga taatgatagt aataaaagtg tattgaaaag
    59401 tacaactaaa ttaactgcta taggaaattt gagtgatagt atattacagc agtgtttaaa
    59461 tgtaacaaaa aatataggcg attctaatac tggaagagaa tatacagtag aagatgctgc
    59521 taatgcagtg aaaaaactat taggtgtgaa gaaattttat tacgaaccta attattcaga
    59581 agatgaagat ttaatatttc tactagataa aaattttgat ttttcaggaa aagagtacta
    59641 tgtatttgct tacattaaac agggtgcaga gggtgatgtt agatactgtg tagctaaaaa
    59701 tgatatgagc aaagtttata catatgatgt taatggtaat atgaaagtat gtaatccaga
    59761 tgattataaa aataaaggaa gtataacaga ggaacaagca aaacagatag cattaaaaga
    59821 atgtgctaag agacataaag tcagtatcaa taacttagta gttgatatga tagattttag
    59881 agatgatata tatagtggta atgtctatgc tgttaaaatc aattcaaaaa atagtaatgg
    59941 tacttttggt tggtttttta tagatataga aactgggaaa gtttataatt aaaattagaa
    60001 cttttaaaca agtgttttta attatataat ttaccataat atgttataat atttttagca
    60061 agaagattta acttacaatc tatagagtgg agttcatgta caaaagatta tcctcccaac
    60121 gattcgaagg gaggtgagtt catggataac tttttgttta atgttttagc tagtttaaca
    60181 gctagtgtgg tagtttactt aattagtaaa ctattcaaaa aagcaaaaag ccactctcgc
    60241 acaaagagtg acttacgagt tgaatttaaa tttatattta aatccaaaaa ataaactctg
    60301 tttatgatga actccactct aacgcaaaat agattgtagt tcttcttgct tttattatac
    60361 cacaaaacat tataaataaa actgttgttt ataaaaaaat gcaaagtaaa attttttata
    60421 aacaatgata aaaattttat tatagagcta ttaacttatt aaatatctgt aaatgagcag
    60481 atatttcata agttaatatt tattgtttac ataaaatatt tggtaaaaat aagtaagttt
    60541 tatatgttat aatagttgta gcaagaataa taatctaaag tggcaagcat gtcagctggt
    60601 gttatatcag tttatattta tgataaaata aaaatctccc aaacgccaat aagaatgatt
    60661 taaaaaaata atattttcac ttaaaaataa tcactcttta taggagtaaa ttattttctt
    60721 gattttatta tactacaaat tggtacagat atttaaaaat aatatattca taatattata
    60781 aatagttttg cagtgagcga tatttttgat aaaatagggc ttaacagttg aaacataagg
    60841 cattgagggt atatgataaa tattatcatt tgcactactc gtggttcact gcaaatttga
    60901 gagaattgta tagatgtaag tcttggaaat gctcaattta ttttggggtt ttatattaac
    60961 taagtggtat gtaaagaagt gttgatattt atattgtcta tccccgctag cttgttttat
    61021 attaactaag tggtatgtaa agtcgtaaat tacgaccgta cctttcgtaa aataacaatc
    61081 gttttatatt aactaagtgg tatgtaaagc tttttgagta tgagtacaag cataggaaaa
    61141 ttaatagttt tatattaact aagtggtatg taaagaacaa aaaagataca tctgtaacta
    61201 atttttatac tgttttatat taattaagtg gtatgtaaag acagatataa tatcaaaata
    61261 aggttaggac ttttaaaagc atagccatat cagtaaaaat ttaattatca tttaaaaaat
    61321 aaatttttat ttaaagaata cacataaata tttccagact caactctctt aaactatttt
    61381 catatctttt agtagatacc tttgttgttt tttaatcttt agcaacttgt tcttgagtga
    61441 acctcttatt ttttctaagt tatttcaagc ttttcaaaaa attctctatt tatattcatc
    61501 acacatataa tacaattaat tcagctttaa ttgccaatat ttagtttttc tgtatctgat
    61561 aaaccaagaa tataatcagt atataaacca aaaattttag caaatattat taacccatcg
    61621 tctcttgttg gtctttcacc agactctatt ctattcataa cacttgtatt tatatttgtt
    61681 ttttcaagca attctttttg agaactattc atattttccc taatatattt aatcctttga
    61741 tttacatcca tacataatta tctcgaaaag tttctgtttt ggaaatattg ttattgaaat
    61801 atagcaatta atgtgaatat atgaaaaaga tacactatga ttttataaaa aagaagacat
    61861 acataaaatt tatacttaca aagtgttgca aatgagttag gttttaaaaa tgcatcaatt
    61921 tattttaagt acaggaaagg ggaatattca attagagttg atatgttacc tataaactat
    61981 ctaagatact tgattatgat atagaaaatt tttttacaaa ttaaatttct aagatagaaa
    62041 tttaattaag aggatgatga ggatgaataa tttacaagta atataaagaa ataataagag
    62101 aattttaaat gcatagcaac tagcagatat atatgaaaat gatgtaaaca atatataaac
    62161 taacttcaat agaaataaag agaatgtaaa ttatgtttta ttacaattcg agtatttgaa
    62221 agaatttaag aactaatcta ttaatagtca gttgatttca aaacattcta gtcaattata
    62281 cctttggatc gaaagatgtg caaatagaca ctgcaaaata ttagatattg ataaaacttg
    62341 ggaacaattt gacaatttag agaaaatata tttcaagatt aagcgagaga aactaagctg
    62401 tatagaagat gtattaatag aaaatttaag atttaaggat acaaattaat aaagcaataa
    62461 tatggcatta gatgtaaaaa tagaagttaa aataataaaa gatgttgtta tattaaatat
    62521 aacacattgg aaaaaagaaa caagtctatt aacagttaaa atagctagaa gtcaaggtga
    62581 tttaagttat gtaaaatatt ttgctaatga gagctaagag cttcttaaca agagttttgg
    62641 tgtgtctctt gaaacaaggt taacaattaa taaaagacga atggcagaag aaggcgtatg
    62701 taagtttaaa agagataagt taaacaaact agatactatg taagaggata agaaacttat
    62761 agaagaatat gttacttttg taaaggattt agctttaaaa tatagaatat aaagtgattt
    62821 taagtaaaaa ttgtaacaat taaataagta taagacaagt ttatgagttc atattttata
    62881 acaaggggtg atgttatgaa aatactacaa caatttaaac catacaaata tgataaagaa
    62941 aaaaatatag aatatgatga aaaaattata gctaatcaaa acacagaagt ttatatagta
    63001 tatccacgta tatctgatga agaaaatagg agaagatggg aagagttcaa tgaagtagct
    63061 aaagaagtag ctattaatat agctatgaag aaagttgaga cagtagaaag ttaagagaat
    63121 agagaagttg ctaatactta gcactttctc atagaagaaa attggacaac tatttttaaa
    63181 taattaggaa taaaaaagtt aaatcatatt tgaaaaaagg cgataaaatt gttgagtatt
    63241 gttattagta ataagaatat attaactatg tattaaaaga aattataagt ttttagtaaa
    63301 tatagtattt aaggatatta aaactggtaa aaaatatcat ttagactatt aaataaaaaa
    63361 gtgctggtca aagtagcaac acaataaata aaaaaactta tagaaattat aagataaaaa
    63421 gatgagattt gaaatggtcg aagttaatat aaaaattaaa ggtgaagtaa gtgaaataat
    63481 taactcaatt agaggtatat ttaatagctt tgatgaagaa ttaatattag atataaaatc
    63541 agagtaagaa tataaaggta gatacgtaga aagttataag taattcaaga cttaaattaa
    63601 tttctagttt ttttaatgca aaaatttaat aaatttcaaa atataataat tctgacatct
    63661 aaaaagagct attaaaaatg aataatattg actattaaga tatgaatagt gtacatatat
    63721 taaattaaga tatcaagtag gttaatttta tataat
//
LOCUS       DAYAKB010000017        62274 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.017, whole genome shotgun sequence.
ACCESSION   DAYAKB010000017 DAYAKB010000000
VERSION     DAYAKB010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 62274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62274
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.017"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..393
                     /locus_tag="ACGI3L_001259"
     CDS             <1..393
                     /locus_tag="ACGI3L_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196984.1"
                     /translation="VKGFNIDKIDFVYSVKPIDVFLKTFPTLLWYTTFPLMILTLTKN
                     RFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYMPNNIDVRFNELKNYFF
                     INRGSLVVISIIIVSYIARKSTVLKKSK"
     gene            complement(489..1322)
                     /locus_tag="ACGI3L_001260"
     CDS             complement(489..1322)
                     /locus_tag="ACGI3L_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HFG9196985.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCA
                     KKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(1390..2019)
                     /locus_tag="ACGI3L_001261"
     CDS             complement(1390..2019)
                     /locus_tag="ACGI3L_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HFG9196986.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            2329..2988
                     /gene="cprR"
                     /locus_tag="ACGI3L_001262"
     CDS             2329..2988
                     /gene="cprR"
                     /locus_tag="ACGI3L_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HFG9196987.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            3199..4257
                     /locus_tag="ACGI3L_001263"
     CDS             3199..4257
                     /locus_tag="ACGI3L_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFG9196988.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPEKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            4508..6652
                     /locus_tag="ACGI3L_001264"
     CDS             4508..6652
                     /locus_tag="ACGI3L_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:4922..4924,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HFG9196989.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            6701..7534
                     /gene="fdhD"
                     /locus_tag="ACGI3L_001265"
     CDS             6701..7534
                     /gene="fdhD"
                     /locus_tag="ACGI3L_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HFG9196990.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            7545..7718
                     /locus_tag="ACGI3L_001266"
     CDS             7545..7718
                     /locus_tag="ACGI3L_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9196991.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            7776..8327
                     /locus_tag="ACGI3L_001267"
     CDS             7776..8327
                     /locus_tag="ACGI3L_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9196992.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            8352..9728
                     /locus_tag="ACGI3L_001268"
     CDS             8352..9728
                     /locus_tag="ACGI3L_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016695 - oxidoreductase activity, acting
                     on hydrogen as donor [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase, group A"
                     /protein_id="HFG9196993.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFSVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            9728..10243
                     /locus_tag="ACGI3L_001269"
     CDS             9728..10243
                     /locus_tag="ACGI3L_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9196994.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(10321..11604)
                     /locus_tag="ACGI3L_001270"
     CDS             complement(10321..11604)
                     /locus_tag="ACGI3L_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HFG9196995.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            11792..12214
                     /locus_tag="ACGI3L_001271"
     CDS             11792..12214
                     /locus_tag="ACGI3L_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HFG9196996.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            12316..13254
                     /locus_tag="ACGI3L_001272"
     CDS             12316..13254
                     /locus_tag="ACGI3L_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFG9196997.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            13440..15464
                     /gene="ligA"
                     /locus_tag="ACGI3L_001273"
     CDS             13440..15464
                     /gene="ligA"
                     /locus_tag="ACGI3L_001273"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFG9196998.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRRIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            15624..16973
                     /gene="rph"
                     /locus_tag="ACGI3L_001274"
     CDS             15624..16973
                     /gene="rph"
                     /locus_tag="ACGI3L_001274"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFG9196999.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRTIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            16973..17443
                     /locus_tag="ACGI3L_001275"
     CDS             16973..17443
                     /locus_tag="ACGI3L_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9197000.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            17637..18923
                     /gene="tig"
                     /locus_tag="ACGI3L_001276"
     CDS             17637..18923
                     /gene="tig"
                     /locus_tag="ACGI3L_001276"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFG9197001.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            19073..19657
                     /gene="clpP"
                     /locus_tag="ACGI3L_001277"
     CDS             19073..19657
                     /gene="clpP"
                     /locus_tag="ACGI3L_001277"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFG9197002.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            19676..20926
                     /gene="clpX"
                     /locus_tag="ACGI3L_001278"
     CDS             19676..20926
                     /gene="clpX"
                     /locus_tag="ACGI3L_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFG9197003.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(20997..21524)
                     /locus_tag="ACGI3L_001279"
     CDS             complement(20997..21524)
                     /locus_tag="ACGI3L_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HFG9197004.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(21512..22024)
                     /locus_tag="ACGI3L_001280"
     CDS             complement(21512..22024)
                     /locus_tag="ACGI3L_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HFG9197005.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            22204..24567
                     /gene="lon"
                     /locus_tag="ACGI3L_001281"
     CDS             22204..24567
                     /gene="lon"
                     /locus_tag="ACGI3L_001281"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HFG9197006.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            24557..25168
                     /gene="yihA"
                     /locus_tag="ACGI3L_001282"
     CDS             24557..25168
                     /gene="yihA"
                     /locus_tag="ACGI3L_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFG9197007.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(25433..26803)
                     /locus_tag="ACGI3L_001283"
     CDS             complement(25433..26803)
                     /locus_tag="ACGI3L_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9197008.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGSVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(26978..27093)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            27381..28460
                     /locus_tag="ACGI3L_001284"
     CDS             27381..28460
                     /locus_tag="ACGI3L_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9197009.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            28851..29531
                     /locus_tag="ACGI3L_001285"
     CDS             28851..29531
                     /locus_tag="ACGI3L_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HFG9197010.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            29524..30903
                     /locus_tag="ACGI3L_001286"
     CDS             29524..30903
                     /locus_tag="ACGI3L_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HFG9197011.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            31074..32159
                     /locus_tag="ACGI3L_001287"
     CDS             31074..32159
                     /locus_tag="ACGI3L_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HFG9197012.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            32213..32572
                     /locus_tag="ACGI3L_001288"
     CDS             32213..32572
                     /locus_tag="ACGI3L_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HFG9197013.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            32625..33497
                     /locus_tag="ACGI3L_001289"
     CDS             32625..33497
                     /locus_tag="ACGI3L_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HFG9197014.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKNIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRGFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            33498..33941
                     /locus_tag="ACGI3L_001290"
     CDS             33498..33941
                     /locus_tag="ACGI3L_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197015.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            33956..34540
                     /locus_tag="ACGI3L_001291"
     CDS             33956..34540
                     /locus_tag="ACGI3L_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197016.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            34793..35830
                     /locus_tag="ACGI3L_001292"
     CDS             34793..35830
                     /locus_tag="ACGI3L_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HFG9197017.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLNGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            35911..36276
                     /locus_tag="ACGI3L_001293"
     CDS             35911..36276
                     /locus_tag="ACGI3L_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197018.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            36281..36598
                     /locus_tag="ACGI3L_001294"
     CDS             36281..36598
                     /locus_tag="ACGI3L_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197019.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            36646..38250
                     /locus_tag="ACGI3L_001295"
     CDS             36646..38250
                     /locus_tag="ACGI3L_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9197020.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            38374..40002
                     /locus_tag="ACGI3L_001296"
     CDS             38374..40002
                     /locus_tag="ACGI3L_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFG9197021.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            40267..41616
                     /locus_tag="ACGI3L_001297"
     CDS             40267..41616
                     /locus_tag="ACGI3L_001297"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFG9197022.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            41772..42851
                     /locus_tag="ACGI3L_001298"
     CDS             41772..42851
                     /locus_tag="ACGI3L_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFG9197023.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            43196..44104
                     /locus_tag="ACGI3L_001299"
     CDS             43196..44104
                     /locus_tag="ACGI3L_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase activase"
                     /protein_id="HFG9197024.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            44109..46478
                     /gene="hypD"
                     /locus_tag="ACGI3L_001300"
     CDS             44109..46478
                     /gene="hypD"
                     /locus_tag="ACGI3L_001300"
                     /EC_number="4.2.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase"
                     /protein_id="HFG9197025.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            46803..47606
                     /gene="proC"
                     /locus_tag="ACGI3L_001301"
     CDS             46803..47606
                     /gene="proC"
                     /locus_tag="ACGI3L_001301"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFG9197026.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEKFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            48204..50960
                     /locus_tag="ACGI3L_001302"
     CDS             48204..50960
                     /locus_tag="ACGI3L_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197027.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDIIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            51092..51571
                     /locus_tag="ACGI3L_001303"
     CDS             51092..51571
                     /locus_tag="ACGI3L_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFG9197028.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            51587..52009
                     /locus_tag="ACGI3L_001304"
     CDS             51587..52009
                     /locus_tag="ACGI3L_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9197029.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            52049..52840
                     /locus_tag="ACGI3L_001305"
     CDS             52049..52840
                     /locus_tag="ACGI3L_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9197030.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            52833..53633
                     /locus_tag="ACGI3L_001306"
     CDS             52833..53633
                     /locus_tag="ACGI3L_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9197031.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            53681..54736
                     /locus_tag="ACGI3L_001307"
     CDS             53681..54736
                     /locus_tag="ACGI3L_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9197032.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(54915..56861)
                     /gene="feoB"
                     /locus_tag="ACGI3L_001308"
     CDS             complement(54915..56861)
                     /gene="feoB"
                     /locus_tag="ACGI3L_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFG9197033.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(56879..57097)
                     /locus_tag="ACGI3L_001309"
     CDS             complement(56879..57097)
                     /locus_tag="ACGI3L_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9197034.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            57303..57812
                     /locus_tag="ACGI3L_001310"
     CDS             57303..57812
                     /locus_tag="ACGI3L_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFG9197035.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            57890..58051
                     /locus_tag="ACGI3L_001311"
     CDS             57890..58051
                     /locus_tag="ACGI3L_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HFG9197036.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            58202..58867
                     /locus_tag="ACGI3L_001312"
     CDS             58202..58867
                     /locus_tag="ACGI3L_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFG9197037.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            58933..60717
                     /gene="pepF"
                     /locus_tag="ACGI3L_001313"
     CDS             58933..60717
                     /gene="pepF"
                     /locus_tag="ACGI3L_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFG9197038.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            60969..61811
                     /locus_tag="ACGI3L_001314"
     CDS             60969..61811
                     /locus_tag="ACGI3L_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9197039.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      62044..62127
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
BASE COUNT        25144 a         6740 c        11009 g        19381 t
ORIGIN      
        1 gtgaaaggtt ttaacataga caaaatagat tttgtttata gtgtaaagcc aatagatgtg
       61 tttttaaaga catttcctac attattatgg tatacaacat ttccactaat gatattaaca
      121 ttaacaaaaa atagatttac aacaatagca atattaatta catatacatt tgctgatata
      181 ttttttattt tacatatgta cccatttgtt agtatgatta atgtaaatgg attttatatt
      241 caaaagatgt tttatatgcc taacaatata gatgttagat ttaatgaatt aaagaattat
      301 ttctttataa atagaggttc tctagtagtt atttctataa taatagtttc ttatatagca
      361 agaaaatcaa cggttttaaa aaagagtaaa tagtttaata tattttttat aatgttatat
      421 ttatatagaa tagtgacttt aaaaaattta aagccactat tttttaatat gttttatcta
      481 tataactatt atttttctag gttttttaat atttcgtaat agtgtgttgt ggctatttca
      541 cttgactcgc cttttttaca aaaagataat ttagatagtt ttggaactac acgttcaacg
      601 acaattttat tacctatcat tttagattca agtatcttca atgcttctaa aaatctatta
      661 tccttttttg cacaattata aaatgataaa acgtagacat aaaggaatag gttataatta
      721 cggaaaggat attcaacttg cataaataag gttccaattc catagtgaca agggccgatt
      781 ggttttttaa tagtccaatg gtcaagtaga aaatctacag ctttgtcaag ttttgattct
      841 ttatttagat aattactaaa acggaatgca tttaatatat taagagttgg tagtggattt
      901 gagtattcag tttctggacc tcgaccaaaa ctaaatttat tgcaacgcca cccaccatca
      961 gtatactgtg tatctaaaaa atgttgaaac gttttttgca ttctaatgtc agatgcatat
     1021 cccatatgac agagtacgtt agcagcattt gcagtatgac aagggtaaat acctccattt
     1081 ggatatagtt tgaaacgtcc atcttctcgc catgtgctaa atatcaagtc agcacattct
     1141 ttaagtaaag tatcatcagg gttcacacct aattctaata gataaagtac actatcaaga
     1201 gtagagaaag gagaaccttt tattaaacgc ttatcaggtg tagtccaata gtctgcacca
     1261 ttatcatacc tgtgtgataa tattatttca atatctgata aagattgatt ttctacattc
     1321 attttttact ccatttcata ttatattcta ttaaatctat caaaaacttt attataatat
     1381 tatttatatt tataattgat ttattttatt taaaattgca tttatagctg tatcaggaac
     1441 aactgctaaa tcttctgcat tgaagtaata aactatatta gaatcaaata atatatttga
     1501 atttggagga aattcatcat ctccaaacca aagtataaat accatagatg tattacccat
     1561 atatgtaaac ctataagcta aatctcccat gtttactttt tcagctccaa ttttctccat
     1621 aactaactta tatttgtcta tttgagatgt aaaaacttct gaaagcctat atagagtcct
     1681 gtttaaaaaa tttggataat aaacattgcc tcctggtatt tctttaaaag ttacatattt
     1741 attagttcta ggaatacctt tagcattgat taaatatcta actatcaaga ttttaagctc
     1801 aaagttattg caaaggctac cattactatt ccaaacttct ccacttggat agtctataat
     1861 atattgtcta tcaaaaaaat tgagtgtgaa tctatttaaa tcattattga aaggtatatt
     1921 acttaaatta ctaattgtat gagggtctaa ttctttgagt ttttttcgaa catagtcaaa
     1981 tggaacatta taattatttt ttgttatctt ttcatccata attttttcct ccaatttaaa
     2041 caattaaaag tatatttata aaaagttttc ttattattaa ttttattata tattcaaaat
     2101 attacaataa taaattgtta aataaatttt tatatttaag taaatacgtg taaaatgaat
     2161 ataaagtttt gaaatataaa gtttttgtat ctaagatatt ttatttgtaa aatagtaatt
     2221 aattattgta agctataata tgagagtatt atggttaatg tgaattttaa agatattatt
     2281 aaatatataa attagaatac tattaaacgg ataaatggag gagttattat gtctaagata
     2341 ttagtagtag atgatgagtt agatatgtta aagttgattg aaaatgtgtt gaaaagagat
     2401 ggacatgaag taaaggtaat tagtgatgta gaaaaagcta tgaacatgga ttttaattat
     2461 tttaatctaa taatattaga tgttatgatg cctaagatgg atggttttga agtatgtaaa
     2521 actataagaa ataaggttga ttgtccaata ctgtttttga cagcaaaaaa tatggaaagt
     2581 gatattatgt acggtcttgg tataggtgca gatgactata taaccaaacc ttttggtgta
     2641 ggagaattaa gggctaggat aactgctcat ttaaggcgag aaagtagaga aaaaaagaat
     2701 ttattaacta tctcaaatgt tcaatttaac tttttaggca aagaagtttc aattgatggt
     2761 aaaaaaatta attttactaa aagtgaatat ctaatatgtg aatttctagc aaaaaataag
     2821 ggacaagtat tttcaaaaga aagaatatat gagtcggtat atggttttga tggagaaagt
     2881 gatataagta ctatcacaga gcatataaaa aatatacgaa gcaaattaaa acaatatgat
     2941 atttatacaa tagaaactgt atgggggata gggtataaat gggtgtaata agtataagtg
     3001 ttgtttagtg aaaatattat atatatctac aaaatgtttg taaaatatta atctatatat
     3061 taaaatttaa tttatagatt aatatttttt gtaaatgaca aaattgtaag gtattttgtt
     3121 ataaaatatt aagattcata gtgtatacta ataatatagt atttagtata aatcttgagc
     3181 aaaggatggt tatttctaat ggatagacta aagaatatta gaaagagttt actacagtat
     3241 acatttttat ttttgttaat aggtataaca atttacctag tgtttaaaac attggatatt
     3301 aaaatgctat caaatgttat ggttatggta gataagaagt ttttattcat aggtgctttg
     3361 gcaataatgt gtcacataat gcttgaagga gtagtaatga agataattat agaaagcact
     3421 cacaaagtta atattagatt tattggtttt aagctagcca ttatgggatt ttattataat
     3481 ttaataactc cttttgcttc aggaagccaa ccagtacaga tatatgtact taaaaaatgt
     3541 aaaatgccac ttagtaaggc aagtgcagtt gttaccaata agtctattat cttccaaata
     3601 gtagttactt tttattgtac aatacttgtt ttaatgaatt ttgctatgtt agaaaaacaa
     3661 atgaaaatga ttatgcctct agtgtttcta gggatagcca ttaattcatt tgtcttaatt
     3721 atgataatat tagttatttt aaatcctgaa aaaataaaat attttatgag aattactata
     3781 aagcatttat caaaaattaa gtttttaaaa tttttagata ataagattga atccatagaa
     3841 agttttatag atgattatag taaagcaata aatttttttg caaagaataa aaaggtatta
     3901 atttcaacta taatagtaac ttttattcaa ttaagtgctt actttagtgt ttcattttgg
     3961 atatataaag catttaattt acaaggttat agctatattt atatactgac attacaagca
     4021 tttttatata tggcaatatc tccaatacca acacctggga atgtaggagc taatgaatta
     4081 gcctttttca ctatattcaa atcagtattc cctcaacctt tgatgggata tgcagtattt
     4141 ttatatggtg gatttatgta ctatttgatt ctgattggaa gtggaatatt tactgtaatt
     4201 actcactata gaatgaaaaa cagaattggc agaaatattg ttttaagtga aaactaaata
     4261 agtttaaaga atatatattg agtatattaa aaaatatgtc ataagaacta gaatatttta
     4321 attaaatggt tgaaatataa agattattat gacatatttt ttttgaaatt taagaggaat
     4381 tgtgagaaaa ttgttgaatt taatagatag tattgcaaaa tatttatgat tttgcatatt
     4441 ataaaaacac tcattatctt taagataaat tttacttatc aggggataaa tctaaggggg
     4501 gaattgtatg gagaaaaaaa ttttaacagt ttgtccatac tgtggagctg gatgccaatt
     4561 atatctagta gtaaaagata ataagatatt aagagctgaa ccggctaatg gtagaacaaa
     4621 tcaagaaagt ttgtgtttaa aaggtcgtta tggatgggat tttctaaatg accctaaaat
     4681 tctaacacct aggctaaaaa agccaatgat aagaaaacaa ggtgtactag aagaggttga
     4741 atgggatgag gctataaact atacagcttc aagactaaat gaaattaaag aaaaatatgg
     4801 acctgattct attatgggaa caggttctgc aagaggacct ggtaatgaag caaactatat
     4861 aatgcaaaaa tttatgagag ctacaatagg aactaataat gttgaccatt gtgctcgtgt
     4921 ctgacatgca ccatctgtag ccggtctggc ttactcatta ggtagtggtg caatgtctaa
     4981 ttctatacca gagatagaaa atgcagatgt tttatttata tttggatata atggagcaga
     5041 ttcacatcca atagtggcaa atagaatagt aaaagctaaa aaaaatggtg ctaaattaat
     5101 tgttactgac cctagagtaa ctgaatctgc aagaattgct gatatacatc tacctataaa
     5161 aggtggaaca aacatggttt tagtaaatgc ttttggaaat gtattaatag aagaaggtct
     5221 ttacaataaa gaatttgttc aaaatcatac acaaggattt gatgagtata aagaaattgt
     5281 taaaccatat acagctaaat atgctgaaaa gattacagga atcccagaag agcttataag
     5341 aaaagctatg agagaatatg caaaaggtaa aaaagctatg atactttatg gaatgggtgt
     5401 ctgtcaattt ggtcaagctg ttgatgtagt taagggactt gcatcaattg ctctacttac
     5461 aggtaatttt ggtagagaaa gcgttggaat aggacctgta cgtggacaaa ataatgttca
     5521 aggagcttgt gatatgggag ctcttcctaa tgtatatcct ggctatcaaa atgtaactga
     5581 tgataagata agagaaaagt ttgaaaaagc ttggggggta aaattatctc ctaataatgg
     5641 ttatagttta actcaagttc caaatttagt actaaaagag aaaaagctta aagcttatta
     5701 tatatttgga gaagacccag tgcaaagtga cccagatgca tcagaagtta gagaagcatt
     5761 agatgaattg gaatttgtca ttgttcaaga tatatttatg aataagacag cacttcatgc
     5821 tgatgttata cttccagcta cttcttgggg agaacatgag ggagtatata catgtgcaga
     5881 tagaggattc caattgatga gaaaagctat agagccacaa ggagatgtaa aaccagactg
     5941 gcaaattata agcgaaattt ctacagcaat gggatatcct atgaattata aaaatactaa
     6001 ggaaatatgg gacgaactta gacaattatg tccaagtttc ttaggtgcta cttatgaaaa
     6061 gatagaaact caaggatgcg ttcaatggcc ttgtaagagt gaaagtatgg aagataaagg
     6121 aactatgtat ctgtatgaag gtcaaaagtt ttctactcct aatggtaaag gtaatttgtt
     6181 cgctgctgaa tggagacccc ctatggaagt tgaagatgat gaatacccat ttagtttatg
     6241 tactgtaaga gaagttggac actattcagt aagaacaatg actggtaatt gtagaacact
     6301 tagttcatta gaagatgaac caggacgtgt tcaaataaat tctaatgatg ctgaaaaatt
     6361 aggaattgaa gatgatgaat tagttagaat tagttcaaga agaggaagtg taataacaag
     6421 agcaacagtt actgatagag ttaaggaagg tgcaacatat atgacttatc agtggtgggt
     6481 tggagcttgc aatgaactta caatagcaaa tttagaccct atatctaaaa caccagagta
     6541 taaatattgt gctgttaaac ttgaaaaact tgaagaccaa gaattagcag aaaaatgtgt
     6601 aagagaagag tatcaaagtt tgaaagacaa aatgacagct acaaatatct aatgatttat
     6661 tagatttaag atttataaaa ggcagaaagg ctaatatttt atgaacaata tatactcaaa
     6721 aactaaatta caagaaaata gtaaggataa agtttttgaa aatagttata gtctagtgga
     6781 ctacaaatat ttaaattctt ttaatgtaga agtaagcaaa ataaatgaac atgaagtatc
     6841 aatagataat gaagaaataa ttgcagaata tccacttagt tttattttaa atgataaata
     6901 tgtaaataca tttttatgta ccccatataa tttagaggaa cttatagtag gattcttgaa
     6961 aacaaaagga tacatagaaa acaaaaaaag cttattaaaa tttgagataa atgagagtga
     7021 acgttttgca aaagtaacta ttcaagagaa acaaaaaaat caagatgagc aaattatatt
     7081 tttaaattca ctagactata taacatgtgc tcctgtaaag agcaatataa aaataaatta
     7141 tgatacgatt tacagtataa tggataaaaa tttaaattca tcagaattat ttaaaaatac
     7201 tggtggggta catagcgtat ctgtatttaa ttttgataaa aaaatagtca cttgtgaaga
     7261 tgtagcaagg cataatgcaa tggataaggc tattggattt tgtgttttaa atgacataac
     7321 attaaaagat aaaattgtgg ctgtaagtgg aagaatatca ttggaaatga tattaaaagc
     7381 agctatgact caaattccta ttgtagtatc aaaatcagca ccgactaatt tatcaataga
     7441 gctttctaaa aaattaaata taacgcttat tggatttgta agaggaagac ggatgaatat
     7501 ttatgcaaat ccacagagag ttatcaaaaa gtgagaatga atatatgtgt actaaaaaag
     7561 aagagcaaag atattcaaag tgtgaaatct gtggagtatt aattgatgat actgataagg
     7621 tgtataataa cacatacaat ttgtgcaaaa aatgtaaacg aaatataagt actgagaaaa
     7681 tagtgaaata tataaatata tatgatgaaa gtaagtagac atatgatgaa aataactaga
     7741 gggttggaaa tatacaaatt gaaaggtggg ataatatgaa aaataaaata ggctcttttg
     7801 taatagcaga cccaaacaaa tgtacaggtt gtagagcttg tgaagtagct tgttttacaa
     7861 tgcataatca gcataataat gtgggttata cagttggaac agttgatata cctgttatac
     7921 ctagacttta cttagtaaaa ggtgacaatt tctgtatgcc aatacagtgt agacattgtg
     7981 aagatgctcc ttgtttaaac tcatgtccac aaaaagctat agttaaagaa aacaatatta
     8041 tgtctgtaaa tgaagaaaag tgtataggat gtaaaacttg tctgctagca tgtccttttg
     8101 gagctataga cttacttcca caatatgaag atggtaaaga agtagaacaa gtaattttag
     8161 atgaaaataa gaagatagct tataaatgtg acttatgtaa agacaatgaa aaaatagctt
     8221 gtataagtgc atgtcctcag gaagcattaa aacttgttac tccaatagat gacaaaaaag
     8281 ctaagaatag acaagctgca cttagtttat tgttaacaaa taaataaagg atacaggggt
     8341 aggtgacgtt tatgataata aatatagata aggatttatg tactggatgt agagaatgtt
     8401 caaaggtctg tccagtaaat gctattgaag gtgaagaggg aaagccacaa gagataaatt
     8461 tagatagatg tgttatgtgc ggtcaatgtg ttcaaacttg taaatcttat gcctcagtta
     8521 tagatgaagg atttgagttt ttacaagaga aaaaacaaga aagagagata ccagagtcta
     8581 taaatgaacc tatatttgca gcatacaatg tatgtgatat agataaggtg aagaaagctt
     8641 taagtgaccc aaatgtattc actatggtcc aatgtgcacc agcagttaga gttgctttag
     8701 gagaagattt tggatattat ttaggatact taggtgctgg gaaaatggca gcagcactta
     8761 gagctttaaa ttttgataga gtctacgata ctaattttgc agcagattta actataatgg
     8821 aagaaggtag tgaattaatt aaaagagtga cagaaggtgg aactcttcca atgtttacat
     8881 cttgttgtcc agcttgggta aaattcatgg aaaaaaatta tcctaaatta actaatcatt
     8941 tatcttcttg taaatcacct cagcagatgg gtggtgcaat atttaaaact tatggtgcag
     9001 agataaataa tgtagatgca tcaaagatat ttagtgtttc tataatgcca tgtacatgta
     9061 aaaaatatga atgtgataga gaagaaatgg attctagtgg atatagagat gtagatgtag
     9121 tattaactac tagagaacta gcttatttaa taaaagacat gggaattgat tttaaaaatt
     9181 taagagaaga aaaatttgat agtcctttag gtagttatag tggagctgga actatcttta
     9241 gtgttactgg tggggttatg gaagctgcta taagaacagg atatgagctt ataactggag
     9301 aaagtattcc tgatgtagaa gtaaaacaag taagaggaga aaatggtttt agaaagtcaa
     9361 ctattaaaat aggagactta gacttaagag ttggagtagt aagtggatta aaaaatgtaa
     9421 taccagttct tgaagacttg gaaaaaggaa aattagatgt agattttatt gaagttatga
     9481 cttgtcctgt tgggtgtgta agtggtggag gtcaaccaaa aattttacta gaagaatata
     9541 aggaattggc ttatgaaaat agaacaaaag caacatacgt gcatgatgaa catttagcaa
     9601 ttagaaaatc tcatgagaat cctgatatta aaaaactgta tgatgaatat ctggtagaac
     9661 cattaggaga aaaatctcat catctattac acactacata ttgtatagga aaggaagtgg
     9721 ctaagtgatg aactattttg ttatagcaga ccctgataaa tgcataggat gtagaacttg
     9781 tatgatagga tgtgtagttg cacattcaga tgaagatatt ttttaccaaa atccagatga
     9841 aataaatttt aatccaaaac tttctgtcat aaagacaaaa gaagtaagtg ctccaataca
     9901 gtgtagacat tgtgaagatg ctccttgtgc aaaggcatgt ccaaatggtg gtatagttag
     9961 ggttggtaac acaataaaaa taaatgaaga aaattgtata ggatgtaaga cttgtatgtt
    10021 agcatgtcct ataggtgcaa tagacatagt tacattaaaa gatgtagatg aaggaaagct
    10081 ttgctttaga gaaagaatga cagcaaataa gtgtgatttt tgtatagaat cgccagaagg
    10141 gcctgcatgt gtaaatgttt gtccaactaa ggcatttact atagttaagg atgaggatat
    10201 agatagtaaa gttaaaaata agagaaaatt agctatattg taatataaaa aagatggagt
    10261 tttatttatg attaaaagct ccatcttttt tattataata tttatatatc taaaaatcaa
    10321 ttattgcatt agtttatcta atctttcttt attcaatttt ttcattccta tagaagttat
    10381 aataagtaaa gtataggcaa ttataactga taaaattata atagaccaag aaaatctgta
    10441 tccaaaatta tcaactaaca atccaaataa tgttgaacct aatgcaaatc ccactgcaaa
    10501 aattaattgt acgattccat atatgctacc aaactccttt tgaccaaaga aagagccagt
    10561 taaataagca ggaccaatca tataagcaaa tacagaaaga cctttcaaaa tggcaaatac
    10621 aaatgcaaaa gtagaagatt tatctaccaa tagtaatgat aaagttgcta taagaaccaa
    10681 tacaaaagat ataataagtg gctttgtttg accgaattta tcaaacaata atcctccaaa
    10741 taaattacca atgagagcaa ataaggcaaa tgtggagcct actgttccta ttagaatagg
    10801 atttagataa tttctaagat aagttggata ttgtacagat aatgatgaaa catatatacc
    10861 aacaaatata aatccaatag tcataatcca aaaatattta atttttttag cttcttttaa
    10921 tgtataaccc catactgaag gagaaattgt atcagatgct ttctcttttt tacctttaga
    10981 ttttaccttt tcattaatat ctttaggcat cctgagtatg aataatatta caggtatacc
    11041 aactattaat gctataattc caaatattag ataagaacga ctgtatcctt gagttgctaa
    11101 taagcgaact gcaagtggtt gtagaaatat actaccaata gaaccaccag caaaagcaaa
    11161 gcccaaagct tttcctttgc tttcttcatc aaaccaagca cttattaaaa caggtattcc
    11221 tatagcagat ataattgtag cgccaatttg aacaatacat gatacagtgt aaaattgcca
    11281 tagttcagta catatagaaa aagtagcaaa agcaatacta gaaattatac aacctaataa
    11341 atatagtatc ttaatattga ctttagaaaa taatacacct ataaaaggtg atgcaattgc
    11401 tgaggcaata gtaccaatag tgaatattag agaaaaagaa gctaaactaa agccttctcc
    11461 ttctacaaca taacttataa attgaggctg tatacttgct acaatactaa atggaacagc
    11521 ttgtattaac atacaaccaa gtactataac ccaagcattt gaaaagtttt taatgctaaa
    11581 tttattgttt agtaatgtat tcatggtatc tctcctttag gttatgattt gtagatatta
    11641 atctaattat tctaatttta tatattagtt ttggatagcc taactattta aatataattt
    11701 gggtattaat ataaaaatta actataaaaa ttgattattt taaatgtatg gggtaaatta
    11761 aagtatataa ataaatgaaa ggatggataa aatgtcattt gaaaaaataa ataataataa
    11821 cctagataaa atacacaata ggaagtgtat tatgcttgta aactttaata aaaaagaatt
    11881 atcattaatt aaaaatgtaa gtaactttgc tggaataaga gaccatatca tcttaagtga
    11941 taaaaatgga gagaatataa taagagacat tttagatgga aatatatcaa atgaatgtga
    12001 aaatgggatt aagagtaagt ctgtaatatt taataacact ccaagtacac aagtaaatgc
    12061 atttttagaa gggctaaaaa aagtgagaat aaatagacct tttacagcta tggtaacaga
    12121 gacatctatt gattggacat tgaataattt aatagaaaat ttagttcaag aacgtaatgc
    12181 tatgtcttta ggaaaaacaa ttgaacataa gtaaatttaa gatatcttat agtaatttta
    12241 actaatgtac attgagtatc atattatatt ttagaataga aaattttaaa tgtgggtaga
    12301 tggaggagat ttgagatgaa agttttattt acaataaatt atggaaaaga aaaatttgat
    12361 aaaataagag aattaggcta tgatgtcata cattactctg aagatagtat tgaaaataat
    12421 gaggatgtaa atacagcaga tgtactagtt acatacaatc catttgagag attagatatt
    12481 tctaagatga aaaatttaca atatatacag acaactagtg taggtataga ccaacttcca
    12541 aaagaagagg tattgaagag aaatattaag atagctaata atagaggcgg atatagtgta
    12601 cctattggtg aaagtattgt attgtatatt ttagaaatat ataaaaatag tgcaaaattt
    12661 tttaaacaac aacaaaataa agaatggaag atggattttt ctgtatcaga attgtatgga
    12721 caaagagttg gatttttagg aacaggtact atatcttcag aagcagcaaa aagattaaaa
    12781 gcttttggtg tagaaatatg gggtgtcaat actgatggaa gtagtaaaaa atactttgat
    12841 aagtgttttg ctactgagga tatgaatatt gtatttgaag aatgtgatat agtagttgta
    12901 gcaatgcctt ctacaaaaag tacagatgga atagtaaaca aagatatgtt taaacttatg
    12961 aaagatggtt ctgtatttat aaatgtaggt agaggaaata cagttaatca gaaagattta
    13021 gaagaatgtg tagagaaatt tagaggggta gcattagacg tatttgaaag tgaaccttta
    13081 aacaaggaca ataagttgtg ggagtgcgaa aatgtcatag taactcctca taattcttgg
    13141 gtgtcagata aaaacaaaga gagaacattt aatatggttt ataataattt gaaacactat
    13201 ataatggaga ataaacctgt agataatgtt gtagacatat caagaggcta ttaaaaataa
    13261 aaaattttga taaaaataaa aactcttatt agtcgtatta aagatactaa taagagtttt
    13321 ttttgtaata aatttaaagc ccaaaaagtg atatactaaa aaatatataa ataggagata
    13381 attaattata gggaaatttc aaaataattt aattttaaaa atatgaagag gtgcaaaaag
    13441 tgagcgtaaa agatgaaatt aataaactta tagagacaat aaactaccat aatgaaaggt
    13501 attataatca agatagccca gaaatatcag attatgaata cgataagtta atgaaggagt
    13561 taatttcttt agaagaagaa catccagaac taaagagaat tgattctcca acaaataggg
    13621 taggaggtaa gccattagat aagttcaatc aaattgtaca taaaactcct atgttgagtt
    13681 tatcaaatgc tttttcagag caagatttga gagattttga taagagagtt caagaatatg
    13741 tgggagaaaa tgttgaatat gttgttgaat ttaaaataga tggtctttct gtaggtctaa
    13801 cttataacaa tggagagttt gaaaaaggag caactagagg agatggagtt gtaggagaag
    13861 atatttctca aaacttaatg acagtaaaaa gcatacctct taagataaat gataaaaaag
    13921 aactaatagt tagaggagaa gtatatatat caaaagataa ttttagaaaa gtaaatgaac
    13981 aacaagaaga acaagaacag ccattatttg ctaatccaag gaatcttgca gctggttcat
    14041 tgagacaatt agacccaaaa ctaacagcaa agagaccatt agatatattt gtatttaata
    14101 tggaaaatat agaagaatac gatttagaaa gtcacagtga atcactagag tacttagaaa
    14161 aactaggatt ttcagtaagt cagagttata aagtttgtaa aagtatagat gaagttattg
    14221 agcatattga atactggaca gataacaggg gtaatttaga ctacgaaata gatggtatgg
    14281 taataaaagt aaacaatata aaacaaagag acgaaatggg atatacagcc aaaagtccta
    14341 gatgggcaat tgcatataaa ttcccagcag aaaagaagaa aactaaaata gtagatataa
    14401 tagtagaagt tgggagaact ggtacaataa caccttcagc aattcttgaa ccagtcagac
    14461 ttgcaggtac cactgtaagt agagctacac ttcacaatga agattatata agagaaaaag
    14521 atataaaaat aaatgataca gtattagttc aaaaagcagg ggacataata cctcaagttt
    14581 tagaagttat aaaagaagaa cgtactggag atgaaataga ttttaaaatg ccagaaaagt
    14641 gtccagtttg ttcagagcca acaataagat tagaaggaga agctgctgta aaatgtatca
    14701 atatgtcttg cccagcccaa ataagaaggc gaattataca ctttgtgtca agggatgcaa
    14761 tgaatataga tggattggga gaatctataa ttacactgct attaaatgaa aaaattattc
    14821 aagatgtatc tgatttatat tatataaaaa aggaagatgt agtcgaccta gagagaatgg
    14881 gcgaaaaatc tgctgacaat ttaataaatt caattgaaaa atcaaaagaa aatgatttat
    14941 ggagacttat aaatggatta ggtattaaat ttataggagt taaagcagct aagatacttg
    15001 catataactt taaggattta gatgaagtaa tttctgcaac tagtgagcaa ctagaagaat
    15061 tagaggaatt tggaagtata atggcaaaca gcgttgtcga gttttttaag gaagacaaaa
    15121 atatgaacgt tataaacaag ttaaaaaatg taggagtaaa tacaaaatca ttggataata
    15181 caggtgaaaa agtagaaaaa atatttgaag gtatgaaaat cgtattgact ggtacacttc
    15241 ctacattaaa aagaaatgat gcaaaagata tgatagaaaa aagaggtgga aaagctacat
    15301 ctagtgttag taaatcgaca acatttgttt tggcaggtga agaagctggt tctaaactta
    15361 ctaaagcaaa tgatttagga attaaagtta tagatgaaga gagattttta gaattattaa
    15421 agttatcatc gaaagatgaa gtaaaagctg tattagagag ttaaaaagtc gcttaattta
    15481 gtagaaaact actataatta atgatagaat agttcagtaa gctaataaga ttacgaaaaa
    15541 tgacaataat taatatttga caaaattaaa aattataaaa ataaatttat aaaaaataaa
    15601 aaatatgaga aaggatataa aaaatgacca gaagttatga tagaagtaat gaacagataa
    15661 gacctgtaaa gataactaga gattatacaa agtatgcaga aggttctgtt cttatagaaa
    15721 tgggagagac aaaggttata tgcactgcat cagtggaaga aaaagttcct ccttttttaa
    15781 gaaatagtgg tactggatgg ataaatgctg aatattctat gctaccaaga gcaacacaac
    15841 aaagaaagat aagagatgca tctaggggaa aaattgatgg aagaacacaa gaaatacaga
    15901 ggttaatagg aagaacaata aggtctgttg tagacttgaa taaattagga gaaagaacta
    15961 tttgggtaga ttgtgatgtg attcaggcag atggtggaac tagaactgca tctataacag
    16021 gggcatttgt agcagttgca gaagcaatat ataaattata taaagcaaag acaataaaag
    16081 agatgccaat aacaaatttt gtgtctgcaa ttagtgttgg tattgtaaat ggaatacaca
    16141 tgctagattt atgttatgaa gaagattcta aagcacaggt agatatgaat ataataatga
    16201 ctgataagtg tgagtttgta gaagtacagg ggacaggaga agagaaacct ttttctagag
    16261 cagatttaaa tttattgtta gagttaggtg aaaaagggaa taaagaatta ataaggcttc
    16321 aaagagaagc tttaggtgaa atatcagatg agatattggg tatggattat ggtaatgaag
    16381 tagtgattgc tactaataat gctcataagc tagaagaaat aggtgaaatc ttaaaagatt
    16441 ttgaatataa agtgtactct ttaaaagatg ttgatttagc aggtatagag atagtagaag
    16501 atggaaaaac atttgagcat aatgcgttga taaaagctag aacaatagca aaaaagacta
    16561 aacttatagc aatatcagat gattctggct tagaagtaga tgctttaggc aaaaaacctg
    16621 gtgtttattc agctagatat gcaggagaac atgcaacaga tgaagaaaat agaaaaaaac
    16681 tgttaaaagc tatgcaaaat gtaccaatga gcaaaagaaa tgcaagattc gtctctgcaa
    16741 tagcagtagt ttttcctgat ggaaaagaat ttgtagtaag aggaatttgt gaaggaatga
    16801 taggatttga agaaaaaggt aaaaatggtt ttggatatga tagcttattt atagtaaaag
    16861 gatatgataa gacttttggt gaaataccta gtgttataaa aaattcaatc agtcatagag
    16921 caaacgcact aaaacttatg aaacaagagt ttataaaaag ggtagtgaag taatgaaaat
    16981 aggcatagta agcgacacac atatgatgat taaaaatatg gaaaaaacaa taccatattt
    17041 gaaagaatgt gacctaataa ttcatgcagg agataacttt actgattcaa gatatattca
    17101 tagcatgact aatgtaggta ttattgcagt taaaggtaat tgtgactttg atgctgttga
    17161 ggaagaagtt gtctttgaag tggcaaataa aaccatattc ttatgccatg gagataagta
    17221 tggtgtaaaa tatggaacta atatgttaga aaaaaaggca actgaagttg atgctgatat
    17281 agttatattt ggccataccc ataccccatt tagagaaatt aaagatggtg tactttacat
    17341 aaatcctgga agcacttcac ttccaagagg agtatcgtat aaaagttttg tcattatgga
    17401 tatagaagaa gatgacataa aaattgaaga aatacgcata taaaggtgta tttatctaaa
    17461 aaaatggcaa aaaacgctca aaaaattaaa ttttatcaaa taagtacaac gatattaatg
    17521 gaacacttgt aaataaaaaa acttatgtga tataattaag tggttgaatt ataaatagaa
    17581 tgaattataa taccgttatc gggtattaca taaatatcac taggaggatt agaaggatga
    17641 aagcagaact aattaaaaaa gagggtaata aagttacttt aaaaataaca gtagataaca
    17701 ataaatttga agcagcagta aataaggctt ataataaaag cagaaataaa tacaatatac
    17761 ctggatttag aaaaggtaaa gctccaagaa ttgttataga gactcaatac ggaaaaggta
    17821 tattctacaa tgatgctata gaaatattat tcccagaagt ttatccagaa gctatcaagg
    17881 aattagacat agacccaata gacaatccag atttagatat agaagaaata agtaaagaca
    17941 atgggttggt tatggttctt aatgtagaag ttaaaccaga gtttgaatta ggaaactaca
    18001 agggtataga aatagctaag gttgagaata ctgtaagtga cgaaaatgtt gatgctaaac
    18061 tacaagaaat ggttgaaaaa aatgccagat tagtaagtgt agaagacaaa gctttagaag
    18121 atggagatac agctataata gacttcgaag gttttgaaaa tggtgtagct tttgatggtg
    18181 gtaaaggtga aaattataac ttagttatag gttcaaacac atttatacca ggatttgaag
    18241 aacaattagt aggtaaaaaa gctggtgaag aagtagaagt taatgttact ttcccagaag
    18301 aatatcactc acaagattta gctggaaaac cagttgtatt taatgtaaaa ataaatgatg
    18361 taaaagtaaa agaattatct gcacttgatg atgaatttgc taaagatact agtgaatttg
    18421 attctttaga tgaattaaaa gcagatgtaa gagctaagtt agaagaagaa gctaaaaata
    18481 gagcagatgc agaaactaga aattcagtag tagaaaaagt tgctgaaaat acagaaatag
    18541 aaataccaga agttatgata caacatcaaa tagataatat gttaaatgaa cttaactacc
    18601 aattacaata tcaaggattt ggattacaac aattactaga gatgactggt agaactatgg
    18661 aagaattaag agaagagaga aaagaagatg ctaaaaaatt agttaagtct tctttagtat
    18721 tagaagcaat aactaaagct gaaggaattg aagcaacaga agaagaattt aaggctgagt
    18781 tagaaaaaat ggcttctgct tacaatatgg aagtagaaaa aatagaagct tctttaagag
    18841 atgctgacaa agaagatata aaaggtcaaa taaaaataag aaaaacaata gatttattag
    18901 ttgataatgc aacaatagct taataaaata aacgctaact aatatagttg acgttatgaa
    18961 atgtttagta tataatgatg tgcaaatata atttagttaa atgcgtataa taatttacag
    19021 tagcttaaaa aaagctactg taaattatat agaataaagg gggtatgaaa ccatggcatt
    19081 agtacctgta gttgttgaac aaacaggaag aggagaaaga tcttatgata ttttttctag
    19141 actattaaaa gacagaataa tcttcttagg agatcaagtt aacgatgcca cagcagggct
    19201 tatagtagca cagctattat ttttagaagc tgaagaccca gacaaagata tacatttata
    19261 tataaattct ccaggaggaa gtataacttc tggaatggct atatatgata ctatgcaata
    19321 catcaaacca gatgtaagta ctatatgtat aggtatggct gcttctatgg gagcattctt
    19381 gttggcagca ggagcaaaag gaaaaagact agcactacca aatagtgaaa taatgataca
    19441 tcaaccatta ggtggagctc aaggtcaagc aacagatata gaaattcatg caaagagaat
    19501 tttaaaaata aaagaaactt taaatgagat attatctgaa agaactggtc agccattaga
    19561 aaaaattaaa atggatactg aacgtgataa cttcatgagt gcactagaag ccaaagaata
    19621 tggtttaata gatgaagtat ttacaaagag accgtagata gagagaggtg ttaatatgtc
    19681 taaatatgaa gaaaaacgac aattaaagtg ttcattctgc ggtaaaaatc aagatcaagt
    19741 aagaagatta attgcaggtc caaatgtata tatttgtgac gagtgtgttg aactttgtga
    19801 cgaaattatt caggaagaaa tagaagatac tatagatgaa gatactacat ctttaccaaa
    19861 accaaaggaa atgatggaga ttctaaatga ttatgtaata ggtcaagaaa aagctaaaaa
    19921 agctttatca gttgcggttt ataatcatta taagagaata tacagtaaaa aatctagtag
    19981 taaggatata gaaattcaaa agagtaatat acttttatta ggacctacag gttctggaaa
    20041 gacattactt gctcaaactc tagcaagaac tctaaatgta ccttttgcaa tggcagatgc
    20101 tacatcattg actgaagctg gatatgttgg agaagacgtt gaaaatatac ttttaaaact
    20161 tattcaagct gctgattttg atatagaaaa agctgaaaga ggtataatat atatagatga
    20221 gatagataag attgcaagaa aatctgaaaa cccatctata actagagatg ttagtggtga
    20281 aggtgttcaa caagcacttc taaaaatatt agaaggtact gttgcaaatg ttccaccaca
    20341 aggaggaaga aaacatcctc atcaagaatt tttaaagata gatactacta atgtattatt
    20401 tatattaggt ggagcttttg atggattaga gaagataatt caaaaacgtg gtggagataa
    20461 aacactaggt tttggagcta aaatagaaag taaaaaagaa ttagatttag ggaagctgta
    20521 tgaaaaagta cttccagagg atttattaaa atatggtata ataccagagt ttataggaag
    20581 aataccagtt ttagctactt tagagttgtt ggatgaagat gcattaatgc agatattaca
    20641 ggaacctaaa aatgctctag taaaacagta taaaaagtta ttggagttag atgatgttga
    20701 gctagaattt gaagaaggtg ctcttcgtgc aatcgctaaa aaggccatag aaagaaatac
    20761 aggagctaga ggacttagaa gtatagttga aagcgtaatg atggaaacta tgtttgaagt
    20821 accatctaga gataatataa agaaggttat agtaacagag aaatctgtga acgaagactc
    20881 agtaaatcct atcatagtac ttaaggatca agaggaaagt gcataagatg atgaaaagga
    20941 gctttaaaag ctcctttttt tatgttaata tgctaaatat aaaataggta tcattattat
    21001 aaaaatgtga gtaatatacc tagaatacca aagacgaata caattgcaat ggaaccaatt
    21061 tttcctttat ataaaagata aaatgatgct ataaatgcaa ttattccata taaatcccaa
    21121 ttaacttctt tggcagatga aaaagctgct gataatatga atcctagagt aattggtcta
    21181 agaactgtca ataagttttc taccttttta ttatttttaa atttagaaaa taactttgat
    21241 ataatagtta gacctattaa tgcaaaaatt gtaacaccaa tagttgcagc tagagaacca
    21301 aagaagccag cagtcttaaa tcctacaaat gtagcactat ttattgctac aggacctggt
    21361 gtagattgtg atatagcaag taaatccaaa aactcttgat tagttataaa gtgatattta
    21421 gatataaatt cttgctggat aaatggtagc atggcataac cgccaccaaa actaaatgcc
    21481 cctattttaa ggaatattaa gaagagtagt attatttctg acatagacta tatacacctc
    21541 ctccaattat taaataaata gggcttatat tgaatacacc aacagataaa actgctataa
    21601 ttaatagtag tatgttagtt ttagactttg gtagtttctt gaacatgctc gtaaaagaat
    21661 acaatataag agctattaca acaggcgcaa ctcctttaaa aaatccatct aaaattttag
    21721 atgatgaatt tttaaagtat agatacgata agactaagac tatacaaaat gatggtaaag
    21781 cagagcctaa ggtacatata agaactcctg gtataccata aagtttatat cctaataata
    21841 cagatatatt aactgccagt actccaggat aactttgagc tatggataaa taatcaataa
    21901 attcttcctg ctctaaaagt ttttgtttgt ttacaagttc atcttgtata agaggaacca
    21961 tagcgtatcc accaccaaat gtaaacgcac caatttttaa aaaggttaaa aacaatttca
    22021 acataataga aacctccaaa agataaataa catctaagta tactaatatt aatattatat
    22081 cataataaaa agataatata gtatgatagt attctaagaa tttatcatta atgttgaaaa
    22141 ttaacttgtt caaatatata atattaaaag caaagcaatt agactagaaa aggagtaatg
    22201 ttgatggaac aaaattatac taaaatagat catgaattac cattaattcc tctaagagga
    22261 ttagctatat ttccatatat gatattaaat tttgatatag gtagagagat atctcttaaa
    22321 gctttagacc aagctatgat ggatgaagaa cttatatttt taacttctca gaaagaagca
    22381 gaggtagatg agccaggaga agaggatttt tatcatgtgg gaacaatctg taaagttaag
    22441 caaatgataa aattaccagg agatacagtt cgtgttttgg ttgaaggtgt atcaaggggt
    22501 agagtaaaga aaatagaaca agaagatggg tatttcagag cagtaataga agaaatagta
    22561 tttgatagtg ataatttgga tagtgaaaca gaagttgaaa ttgaagcatt tgtaagaaat
    22621 gtatttgatg cctttgaaga gtatataaat attggaaata gggtatcacc agaaatatta
    22681 atatctttag ctgatataga agatgtagat agatttatag atacgatagc tgcaaacata
    22741 tatctaaaat caagccaaaa acaagaaata ttagaagaat ttgatattag aaaaagactt
    22801 gaacttattt attctatatt attagaggaa atagatatat taaaaataga aaagaaaata
    22861 actttaagag taaaaaaaca gatgaataag gttcaaaaag aatattatct tagagaacaa
    22921 ttaaaagcta tacagaaaga attaggtgaa gaagaagata taaactctga agcagatgag
    22981 tatagagaaa agcttaaaaa aataaaagca cctaagacaa ctaaagagaa aatagaaaaa
    23041 gagatagata aattttcaaa aatatcttct atgtctccag atgtatctgt aagtagaaac
    23101 tatttagata ctatattctc attgccatgg aataaagaga caaaagataa attagatata
    23161 actaaggcaa aagatatatt agatgaagac cattatggat tagaaaaagt taaggagaga
    23221 atactagagt atctagctat aagaactctt gctaagtcac ttaaagggcc tataatatgt
    23281 ctagttggtc ctccaggaac aggaaagaca tctatagtaa aatcaatcgc cagagcatta
    23341 aatagaaaat ttgtaagaat atctttgggt ggagttagag atgaagcaga aataagaggt
    23401 catagaagaa cttatgtagg ttcaattcca ggaagaataa ttaatggggt aaaagaagcc
    23461 caaacaaaaa atcctgtatt cttatttgat gagatagata agatggcagc agattataaa
    23521 ggtgacccag cttcagcaat gctagaagta ttagacccag agcaaaataa ggattttgtg
    23581 gaccattact tagaaatacc ttttgatttg tcaaaaatac tatttgttac aacagcaaat
    23641 agtctaagta atataccaag accattatta gatagaatgg aagtaataga agtatctgga
    23701 tatatagaag aagaaaaatt aaatatagca aaaaaatacc tacttccaaa acaaattaaa
    23761 gaacatgctt taaaagaaaa ctttataaaa atagatgatg aaactttaag aagtataatc
    23821 aaccattata caagagaagc tggtgtaaga acactagaaa gaactattgg taagatttgt
    23881 agaaaggttg ccaaaaaata cgttgaagac ccaactcttg aagaggttgt tataaataag
    23941 tctgacctag agacatatct tggaaaagac atgtttaagt atcaacttgc agaagttaac
    24001 cctcaaatag gattagtaaa tggtcttgca tggacagaag ttggtggagt tacacttgaa
    24061 gtagaagtaa acgtacttaa aggtaaagga gaaattgtat taactggaaa attaggagat
    24121 gttatgaagg aatctgcgaa gacaggtatc tcttatataa ggtcaatagt ggacaagttt
    24181 gatatagacc ctgaatttta taagacgaat gatattcata tacacattcc agaaggtgct
    24241 gttccaaaag atggaccatc agctggtata actatggctc ttgcagtaat ctcagcactt
    24301 actaaaagac ctgtgcctgg aaatatagca atgacaggag agataacttt aagaggtaga
    24361 gtcttagcag taggaggagt taaagaaaag ttattagcag ctcatagagc tggtataaca
    24421 aaagtattaa ttcctaaaga atgtgaagct gatttagatg aaataccaga aaatgtaaaa
    24481 gaaaaaatgg agtttgtgct tgtagaacat atggatgaag tattagaaca agctttatta
    24541 aagagtggtg aaaataatga aaattagaag ttcagagata actatgagtg ctgtgaataa
    24601 atcacagtat ccagcagaag gaatcccaga gatagcattg gctggtaggt caaatgttgg
    24661 aaaatcatca ataataaata cattgcttaa cagaagaaac ttcgctagaa ccagtcaaac
    24721 accaggaaaa actagaacta taaattttta tctaataaat aatgaatttt attttgtaga
    24781 ccttccaggc tatggatatg caaagatagc taagtctgaa aaagaaaagt ggggaggtat
    24841 aatggaacga tatctagaaa gtagacaaga gttatgttct atattcctac ttgtagatat
    24901 tagacatgag cctacagcag atgataagct tatgtatgaa tggataaagc actttggata
    24961 taactgtgta gttattgcaa ctaaggcaga taaaatatct agaggacaat atcaaaaaca
    25021 cataagtata ataagaaaaa aattgcaaat ggaaagtagt gaaaaagtaa ttcctgtttc
    25081 ttcactaaaa aagactggtg ttgaagaatt atgggaagag attgtaaatc aatacaatca
    25141 acatggatat gaaataacag tagattaaat ttaaaatgtt aaatattgac atgagattta
    25201 tttgaataat aaatgtaata atagttagtt ttaattatat taatattaaa gcaaaatata
    25261 ggatgcctta aaatagtttt aatgaacttt ttttggcatc cttattgttt ataaacaata
    25321 aatatcagta attttgttaa atactaataa attttagtaa ggtatgggaa aattagtata
    25381 aattagttca actaaaaaat tattgactta tgtagtcagc aataaatagc atttaagaaa
    25441 tagatttatc tgtttttctc ataaagaaaa cagttagtat aagccctata aaacatactg
    25501 atgctgcaat ccaataagac tgattgctag ctataacata ggctgatgtg tgacttttaa
    25561 acttttgatt gtatgtaaga ctttgtgcaa aaaaactact aaaaaatgct gttccaagag
    25621 caaatgataa attacgaata gttgcaagaa aactgcctcc gtatccctgt ttttgaggag
    25681 gaacatctgc taaaatacta ctattgtttg gtgaactaaa tgctcctagc ccaagtccaa
    25741 aaataactaa acatacaatt aaaagataca atggagaatc tgcttttaaa agtgccattc
    25801 caactagtga gatggtcata aatgaaaaag atgctgttag aatgtttttt gcaccgtgtt
    25861 tatcagaaag tgaacctgca ataggtgcta taagtaccat aataagtgga tgtacagtca
    25921 ttacataacc agccatcata ggagataaat tttttaattg ttctaaataa aatggaagta
    25981 gaaaagatac tgccatttga ggaaaataac aagctactcc aatgatattg cctacagtaa
    26041 agtttctatt tttaaataga ggtaggtcaa taaagctttg ttcaaatttt acttctctta
    26101 atgccaacaa taagaagatt ataagtgctg ttatacctaa atacaatctt gtattaccct
    26161 tctcattcat tgcaagtaat ataagcgtag tgcaagatgc gaaaagtaga agacctggaa
    26221 tatcaaagct cttgttttgt tcatccaaaa caggtttagg tagaaattta atgccaagaa
    26281 agactgctat aataccaata ggtatattga taataaaaat agaaggccat ccaaaatgtt
    26341 ctaaaattat acctccaatt acagaaccac tcatatttcc tataccaact acagctccag
    26401 tgattcctat agcttttcct ttttcatttg ctggaaatgc attggaaact ataccaagcc
    26461 cagtagccat taaaatactt gctccaactg cctgaaagat tcttgaagaa attaatgttg
    26521 ataaattgtt tgacatacta cacagaaaag aacctattgt aaatataaaa aatcctaatg
    26581 tgtatagacg atttgaacct actttatcgc caagttttcc gaaaaataac atagtagctg
    26641 ttacaacaag catataagct gttacaaccc actgaatttg tgacatgtta attttaaagt
    26701 cagcagcaat tgtaggattt gcgatattta gtatacttcc atcaagagta gacataaata
    26761 caccaataca gatgataatc aatactatcc atttttgttt catgataaca ctccaatctt
    26821 aatagatttt ataagtacga tataattgta aaataaacaa caaaaaaagc acctgtatat
    26881 taggtacctt gaatgtgtct aatttcatga ataaatacgg tagttgaagg atttgtatag
    26941 attactcatg taaaattaca taaaggtact catatactat tttcttctac catccagatt
    27001 ttactgtcgg ctttggaata tgaccaaatt atgccataag gctcgcgggc ttttaccgcc
    27061 gatagggaat ttcacccgtt tatgaagaaa aacagatgta ttttgtaata ttattttaac
    27121 ataaaattat aatggaaaca attggattta agtaatatcc agctgtatta caatacaaat
    27181 atttcaatat ggacacttaa attgtattta tagatagaat aaggaacagt atgagaatct
    27241 ataataatta gataaaatta acctgttatt agtattagat ggtaagtttt aaatttatca
    27301 aaatcagaaa gctgtaataa aattcttata atatgaatat cttaattaag agatattgta
    27361 aattatgagg aggcgctaat atggaaggaa aggtaaagaa ggcattcccg ggtggaaata
    27421 catcacaagg ctcatattct ttttttgact atataattcc tgaaaatgta aaaagagttt
    27481 tttgtttaaa gggtggacct ggagtaggaa aatcctcact tatgaaaaaa atttataaag
    27541 agtttttgca tagaggatat gatattgatt tatatcattg tccttctgac ccaagttcgt
    27601 tggatggttt agttataaag aaattaggcg tggtacttat ggatgcaact gccccacata
    27661 ctatggaccc aaagctacct ggagctttgg atgagataat taatttaggt gattactgga
    27721 atacagaaga attagaaaag aataaacaag aaatatcagt ttatgataaa gatattagta
    27781 attcatttaa aagagcattt aagtttttaa aatcagcaga accaatcttt agagacatag
    27841 aagaaaaata ttctgattgt atggattatg gaaaagtaaa tttggtcaca gaagaattta
    27901 taaaaaggtt atttgatgga gttaaaagca caggaaatct aaaaagagaa aagcatttat
    27961 ttggttcagc tataactcct gtagggtgtt tagattatac agaaaacatt ttaaaagatg
    28021 taaagaaagt ctattattta gatggagaaa taggaactgg gaaaactaca ttattaaaca
    28081 aagtatataa gaaagctatt gaaaaaggtt taaatgtaga agtttatcat tatccactta
    28141 ttccagagaa aattgaaact gtactattaa ctgatttaga tataggcata actataagta
    28201 cgacttttaa agaagaagat acaattgatt taaatcagtt tttaaataga gaaaaactac
    28261 ttaaatatga agaagatatt aaatttgatg aaaaagtttt agatgattta atttgttggg
    28321 cagtactaaa tcttaagaga gccaagtcta aacatgatat tatagaaagt tactatagtc
    28381 ctaatatgag atttgatgaa gtagggaaat taagagataa gttaattaaa agaattttaa
    28441 aatatgagga aaacttataa acgcatatgt ttaaaattaa cgttagtaat aatataattt
    28501 ttagtaaatt ggtgtagctt tgaggctatg ccattttact ttttttgcta aaaaatgata
    28561 ttaataatct ccaaagccat tatttgtttt tcataattat tatttccttt cctaatttat
    28621 gtttttttat aatatcacaa caatgtttat tgaaagttta tataatttta agaacatcta
    28681 aaaatgcata cttgatattg gtaaattagt gataggagtt caatgtatga tattatatac
    28741 taaagatgaa ttttaatata taactttgat ataataagca tatgtaaatg tttaatattt
    28801 aattaaagaa aattatcata taaaaataaa tttgtaagga gcaatacagt atgaaaaaac
    28861 aatatgtgtt tataatacta gcaagtacta ttttaggtat acttgttgga accatattta
    28921 gagattatag caatgaagaa acagtttata caagcaaaga caagtcaata agaaaagaaa
    28981 taaaaatgac aagaaaatct ataaaagaat taaccaaaga gaaagacaag ttagataaag
    29041 aaattaattc aatgaaacaa aatcaaaaaa attctgaaga aatatcagaa atagaaacac
    29101 ttagagatag tctatcatat tcagatgtaa agggtagtgg gataatatta agtatagatg
    29161 ctatagatga aaaaacaggg aatatagcta atagtataga ctataataag attcttgtaa
    29221 aagttataaa tgaattaaaa gtaaacggag gaaaatacat agaaataaat ggtcaaagaa
    29281 ttaatcaata ttcagaagtt gtacttgcag gaagccatat aaatataaat ggagttcctg
    29341 tagcacaacc atatgaaata aagtgcattg gagataagga gaaactatct aattatgtag
    29401 ataaaggtag taaatattta gatagcatac aaaccaatta tccaatgaaa ataagcataa
    29461 aaactgaaga aaatatctct atgaaaaaaa tgaatatacc taataaatta aagtatataa
    29521 agggtgatta agattatatt agaggaaagc agtttgccaa tgttaatacc agaaaaactt
    29581 gcaaaaaaat ataatgtatt tccagttgag tttcaagatg ataatttagt tgtagaaata
    29641 gaagatgagg atatttatgc tctacaggac ttgagattag ctacaggtaa agaaattata
    29701 ttgaagaagg agaaaaaaga acttataagt gaaaagattg aaaaatatta taatagcttt
    29761 gaacttgatg aggattatgc aaaaaaatta tttgaaaatc ttttagaaaa agctataaaa
    29821 gaaaacgcaa gtgatataca tatagaacca tttaaagaac atttaatagt gagaatgagg
    29881 gtagatggag aactaaagga agtatcaaag tttttagttg atgtctatcc atcattgtct
    29941 acggttataa aattaaaggc atcaatggat ataacagaaa aaaggcttcc tcaggatggt
    30001 agggtggata taaagttagg tggaaattta attgacatta gagtttcatc aataccaact
    30061 gtctatggtg aaaaaatagt tttgaggata cttaatagag atactttttt aaaagacaaa
    30121 ttagaacttg gtttttcaga ggaagctata aaatctataa atcgtataat aaataaaaga
    30181 gcaggaatat tattagtgac aggtcctaca ggtagtggaa agactacaac agtatattcc
    30241 ttattaaatg atttaaaagg aataaataaa aatattatga ctatagaaaa tcctgtagag
    30301 tataagatgg atggcataag tcagattcaa gtaaattcaa aagtagggtt gagctttgat
    30361 gtaggtctta gagcgatatt aagacaagac ccagatataa taatggtcgg agaaataaga
    30421 gatgcagaaa cagctaagat agcagtaaga gcagctataa caggtcattt agttataagt
    30481 actttacata ctaatgatgc agtatcttcc atagctagat tactagaaat gcaaatacca
    30541 ccatatcttt taaatgcctc tcttataggt gttatatctc aaaagttggt tagaaaagtc
    30601 tgcaatcatt gtagccatga gattatgata aaagataatt ttagtggaga tgtaaatact
    30661 aaggtagctg tagggtgtga aaaatgtaat gataaaggat actttggaag aacagcaatt
    30721 tatgaaatct tagaaattaa tgatgatata aagacatgta taagaaatat ggaggattct
    30781 agtactatta aagatgtagc acaaaataat ggaatgataa catttgaaga tagttgtaaa
    30841 agactaataa atgaaaaaat aacgacatta gaagagtgtt tagtagtaaa tgaaatgatt
    30901 taactgaatt gtatagttaa acttcgtttg gtcagttgtc tttatttaat ctattttaat
    30961 taagatgttt gagtataaat tatatttaag tgaaataaaa ttaaatgcat taaattagaa
    31021 aatattaagt ttatttaatt gtaattaata taatttggaa ggtattatag tacatgagat
    31081 tatctaaaaa tatattttat aatttagaaa agttttattt agtattaaat agaatcagtg
    31141 ataaagaaat tagagtaatt tgcaaagaga taggcatatt gctggaatct ggatgtgaaa
    31201 ttacaaaaat atttgaaatc attgagagtc agtcaagtaa aaaagtaaag aacttgctta
    31261 gtatagtatc aaatcatatt caaaaaggta actcaatagc agaatcattt caaataacag
    31321 gtatattttc taaattcttt ataagtatga taaaagcagg agaaactagt ggaaacttag
    31381 atataataat gagtgattta tctaattatt atgataaaga atacaaatta aaaatgaaaa
    31441 taataactat ttcaatatat ccaataatac ttataatatt atctatctta tcaatgttgt
    31501 ttatattcgt atttgtaata cctaattttc aggtggtttt taccaacaat ggaattgaac
    31561 cacctttaat aactagagtt ttaatgggaa tatctacagt ggttacaaat aacttagctt
    31621 atataatatt tagttttata ttgttttcaa taggaagcat ttatttcttt ataacaaatg
    31681 ataatataaa aaaattgatt aattcgttaa aattcaaaat accttttata aaaaaaatta
    31741 atcagttagt agctacaaca agattttcaa gggcattgtc cgttttaatt agcagtggaa
    31801 tacaaattgt ggaagctata gatatgtcag ctagtgttat agacaacgaa tttatttatg
    31861 aaaggttaaa gatttctaat aattatataa aaaaaggaaa tagcataggt aaatctttga
    31921 atttagcaaa tatttttcca aaattattta tttcaatggc aaatacagga gaagaaagtg
    31981 ggaaactaga taaaagtcta aatgtaataa ataaatttta tgaaaatgaa ttaaataaca
    32041 aaatagagca aataatgaaa tttatagaac ctatgctaat tgtatttatg ggattaatta
    32101 ttggtacttt tattttagca atggttgttc ctatgtttga tgcaattact aatttttaga
    32161 gagaaaaata aattttatta gatgaaactt ttgaaaagga gagaatattt aattgataaa
    32221 tttgataaat aaaaaacgaa aaggatttac acttgttgaa atgattgtag tagtaactat
    32281 tttaggcgtt atatctagta tagcattagt taagtatagt aaggttcaag aaagtgccaa
    32341 attaaatgca gactatacga atgctgctaa tatagtaacc gcagctagca tggcaattaa
    32401 tgatgatgaa aagacaatag actctctaag tgtagagaca ttgaaggaaa agggatacct
    32461 aaatactgtt ccagttcctc agagtacatc aggtaaattc gaacttgtca taaatgatag
    32521 cggaacagat ataagcgtaa atataaattc taagcaattt tatccaaaat aatattttat
    32581 attgattgct gtaagtttta aaattatttt tatttaagaa ggagatggct ataattaaaa
    32641 aaattctaaa cttagaaata aatgatgatt atataaggct tgtattttta agaaaaagtc
    32701 ataaaaaagt ttttatagat aaatcaatta taaaagagat taactttgat ataaaaaatg
    32761 atagtaattc gattgagaag attaaatata tagaagatgt agttagattt gtaaaagagg
    32821 agattggtaa atcaaaaata ttatataaaa atttatactt taacattcaa attcaggata
    32881 tagtcattag aaatgttgaa gttctaaata ctaagaaaaa aagagacata ttaagcatga
    32941 ttgaatttga aataacacaa tacattccaa taaacataaa taactattca ataaaatata
    33001 aagttataaa ttctaaaaat gataaattga atatacaagt aattcttttc ccaaagaata
    33061 ttattcaatt aattaagaac atttcagaaa atctaaatat gaatccaaag actataaata
    33121 taaattttga tatattacaa aagcttataa acttaaattt aatagagaat ttttcagaag
    33181 aaggggtatt tatagaatgt aaaaaaagtc agttaattat aaatataaca aaagataaaa
    33241 aaataagaga aacatacttg ctatcaaaag agggaaaatc atatgagttc ataaaaagat
    33301 tattaagggg ttttaagtat gtttattact atggtataga aaattgtttt attgaagaat
    33361 actttaaata tacagataaa tctattgaag taaatccatt aagattaaaa gataaagtaa
    33421 aagtagaaaa taattttgat gcagatttag aagacaatag gataaattat ataaatagta
    33481 taggaatgat tatttaagtg aaagtggata aaacaataaa ttttcttaat ggatttaaaa
    33541 aaactaaacc atgtaataaa atctataaaa taataatagt cttaatttta acgtgtattt
    33601 tatttaaatc atttatgtat gtgaaatcta taaatgaact tgaagattat ataagtcaaa
    33661 ataagctagt ggataaatca aagaacactt taccaacaac agataaaact agagagaaat
    33721 tttctaaaat aaaacttaat gaaataaaaa aaatatatga aacaattgga ataaatagta
    33781 ttactaaaat atcaatagat aaaaataagc tagagatgga aggtgtgtgt agtgatttag
    33841 atgttttaaa caatttaagg aaaataaagt acataaaata ttattacata gacagtattg
    33901 taagagatgg agaatattat agatttagaa taaaaagtta gatgggtgat tatttttgag
    33961 attaaataat agagaaaaaa atctacttaa aatattgtta atattagtta ttatattggc
    34021 aagtgatata gcagtaagtt atttggaaga aaacctaact agtttgaaga atgaaaagca
    34081 aaatataata aataaaataa ataatcaaga taattatcaa ataaaggata ataagcatat
    34141 agatgataaa tatatagaaa gtgttgaatt aaataaaaat gaagaattga aaaataattt
    34201 taataactca tttttagata aaaaaacaaa taaagatata gtgttattag tagaaaatga
    34261 actgagagat attgtgaatg tagaatatat taatcaagaa agtagtttag ataatcacaa
    34321 taaaaaacaa gttaatttag aaataaaagt taatggagaa cttgcaaatg tgttgaaact
    34381 tgaaggtgta atgaagaagt taagactaaa taataaactt gaaaagatag aaattaacaa
    34441 attaaaagtc aataattttg atgttcaaaa tattccaaat gaatataaac aagaaaaaga
    34501 caatattgtt gaatgtaaaa tgacagttag agtcatataa caaaaaagaa tagataaagt
    34561 aaaaaactat tatcaattaa taaaatttta tagaggaatt agttttacga taattcattt
    34621 ctacaagagg gattgttgat gattttatcg aaatcctaat taaagttaat atattgtacc
    34681 aaaatataag tgaatttaat agaatattta cttatactat agattgatta ataaaaaaat
    34741 ggtataataa caaattgtac tttaatttaa taataaggga gtggaagtca tattgttagg
    34801 gagaaatgag ctatgccctt gtggaagtgg caaaaaatac aagaaatgtt gtttaaataa
    34861 agatattgtt tcagaaagag catgcagaaa aactgaactt tcacaaaaac aatatacaga
    34921 tttatattca aagttatatg attattcaag acaggataag tttaaagaag aatgtgaaaa
    34981 agctaaagaa atgttttata taatgcaaaa tgatagtgta aatgaaaaat ttgaaagatt
    35041 ttttaatact tatttaatac aagaccacat aatggaaaat aaaaaggtta tgacagttgg
    35101 ttttcttgaa gaaaatggtg caaacctaag tcaatcagaa gtatcaatat taaaaagtat
    35161 gtttgaatca tacgtaagta tttatgaggt aaaagaagtt tctgctggaa aaatagtatt
    35221 aaaggactgt ttaaatggaa atgaactttg tacagaagat gtaaaacttc tgagaagttt
    35281 taaaatcgga agttgtatga tagctagaat agttgatatt gaaggaacta acatattgat
    35341 agatataact ataagtatat caaatgaggt taaagatata attttaaagg atattatgaa
    35401 tctattcaat caatatcaag atgtatacaa agatatgaag tcgttcttaa tttatcatac
    35461 acatatacta tacaagtata tacaacagct tttagaccca agtatagctg aatatttaaa
    35521 gagagaaaga gataaaaacg atacaaaagt taattcagaa aatgaattag ctgaagaaga
    35581 atgtaaagtt ttagatactc ttaaagaaaa tgtagaaaaa gaaaatatag atgcatgtat
    35641 agagttttgg aatgaatata agaaaaatca tgaaaatata aaaggagctg aaaatggttg
    35701 ggcagctgct gttgaatact atgttaaaaa agaagcagga caacctataa ctcaagttca
    35761 aatatcaaag aaatacgata taagctctag tacactagga aagagataca aggatttaaa
    35821 aatatcttaa ttaattataa aaagctttaa gtcatagata aagaatctat agtataatat
    35881 atgtataatg tttagaaaga ggtattaata atgagtctta gtttaggaaa tgcaattgct
    35941 gtatcaacga actttataaa atctaaccca gctgtacctg tgtacaacgg agaagaaata
    36001 tatgcagtta tttatcatat agaaatagga tataataatg gtgtatcacc tgataccaaa
    36061 caatatataa taatagacta taaagagttt gatttatcta tggataaaaa aaatgaacta
    36121 ataaatattg ctaaagagta ctgtaaatct aaaggtattg tagaaaacga aaaccttgaa
    36181 ataaaccttt tagacaatga agaagcagag aacttcttag aaaaggtgtt taataatatg
    36241 aaggttataa gaggtcttat aactaaaaaa ggataaataa atggactata taggaataga
    36301 aaatataaca ccttatgaaa atacatatga atttagtgta tatgaatatg atgatgaaat
    36361 caccttaggt agtgaaaagt tatatgtatg tgaattaagg gttgtattga ttaaagttaa
    36421 ttctctgtat gttgaaagat tgcataaatc agttgaagca atggtcttag taaaaaactt
    36481 gaaaaaagat ttagataaaa cacttgttgt aaacaaaata aagaattttg tgctagatga
    36541 gatttgggta gaaaatctag taaaagagaa tatagaagtt atatttgtag aaagctagga
    36601 ataaccctag cttttttata ttacaatcta agagaggaaa acaatatgtt aagagtatct
    36661 aatgtaaaac ttggaattga taaagatata tctttattaa aagatgttat acttaagaag
    36721 ctaaaaataa aagaaaaaaa cttagtcaaa tatagtatat ataaagaatc tatagatgct
    36781 agaaaaaaag gaaaaatgga atttgtttat tctgtagatg tagaagttaa agatgaaaat
    36841 aaaatactta actcaaaaat aaaagatgta acaaaaataa aggaaatcag atacgtaaat
    36901 gtacctgtgg gtgataaaaa attaaagaat aatcctttgg taattggtag tggaccagct
    36961 ggcttgtttg caggtctgct tttagctcaa atgggttatg aaccaatcat acttgaaaga
    37021 ggtcttgatg tagacagtag aaccaaagat ataagtgatt tttggacaac tagaaaatta
    37081 aaaaataatt caaacgttca atttggagaa ggtggagcag gaactttttc ggatggtaaa
    37141 cttacaacta gaataaaaga tatacgatgt agaaaagtat tagaagagtt agttcagttt
    37201 ggagcaccag atgaaatatt atactcacat aagccacatg ttggaacaga tatattaaaa
    37261 aatgtagtta aaaatataag aaatgaaata ataagtttag gtggtcaagt tagatttaat
    37321 tcaaaagtaa cagatatagt tgtatcaaat gattctatac aatctgtaat aataaatgat
    37381 actgaaaaaa tagatacaga tacaattata ttagctgttg gacatagtgc aagagatact
    37441 tatgaaatgt tgtattcaag aggtataaaa atagttcaaa aaccttttgc aataggagct
    37501 agagttgaac atccacaaga tttaataaat aaagcacagt acaaggattt ttataatcat
    37561 cctaggttag gagctgcaga ttatagactt atagagcatg tttcaaatgg aagaacagca
    37621 tatacttttt gtatgtgtcc aggaggtagt gtcatagcat ctgcatcaaa tgattttgaa
    37681 atagttacaa atggtatgag tgaacatgca agagataaaa taaatgcaaa tagtgcattt
    37741 ttagtaaatg taacgccaga agattttaag agtgataatc cactagcagg tgttcatttc
    37801 cagcagaagt atgaaaaatt agcttttgaa ttaggtggaa aaaattataa tgcaccagtt
    37861 cagcttgttg gagattttat aaacaataag acttctttga atttaggaag tgttgagcca
    37921 tcatatagac caggatatac acttacaaat ttaagtgaat gtttgcctag cttcgtaaca
    37981 gagactatga gagaagcgtt tatatctctt gataaaaaat tgaatgggtt tgcaatgtat
    38041 gatgctgttt tgacgggagt agaaactagg tcatcatcac caataagaat agtaagagat
    38101 gaaaatactt tagaatcagt gagtattaag aatctatatc catgtggtga aggtgctgga
    38161 tatgcaggtg gtatagttac agcagcagtt gatggtataa aatgtgcaga aaaaataata
    38221 caaaaataca ccaataatac aaaaatttaa cataaactta atgatttttt aatatttaac
    38281 atgaatttaa cattatcact cctataattt gataaaatac aataggttat aaaattttta
    38341 gatacagtaa tctctttaca aggaggaaat aatttgaaca ttataataag tctaatgggt
    38401 ggattaggtc tgttcttata tggtatgaac cttatgggag aaggtcttca aaaatctgct
    38461 gggacaaagc taaaaaagat aataaaacta cttactagta acctatttat gggagttttg
    38521 gtaggtacag gagttacagc agtaatacaa agttcaagtg ctactactgt aatggttgtt
    38581 ggtttcgtaa atgcaggaat aatgacttta aaacaggcaa taggagttat aatgggtgct
    38641 aatataggga ctactgttac agcccaattg gtatctttcg acttaactgg tatggcccca
    38701 gtagcattag gtgtaggtat tatactttat ttatttggaa ataagcctag aataaaaaat
    38761 atagccgaaa tacttatagg ttttggtata ttatttacag gtatggattt tatgaagatg
    38821 gcagtggagc cactaagaga ctatcaagga tttactgact tacttgttac atttggtaga
    38881 tatccactac ttggattatt attgggattt gggattacag caataataca aagttcaagt
    38941 gcatctatgg gtatgttggt tgcactggca gcagaaggtc tagtgccatt atcagcagca
    39001 ctgccaattc tttatggcca aaatattggt acatgtgtaa cttcactgtt atcaagtatt
    39061 ggtgctaaca aaaatgcacg aagagcagct atgatgcatc taatcttcaa tgttttagga
    39121 acggtgatat tcttaatatt cttgaataaa ccagtagtaa gcatggttac aagttgggac
    39181 ccaagcaatg ttgcaagaca aatagccaat acacatacat tgtttaatat aatatctgta
    39241 ttgatacttt taccatttac aaatcttatt ataaaactag ctataaagct tgttcctgat
    39301 agagcaggtg atatagatga agatgaaact aaaactatta aatatataga tgatagaatg
    39361 atagaaactc cttctatagc tcttgcaaat acgataaaag aagcacttcg tatgggtgag
    39421 aaggcgaagg aaagcctaaa tgcatctatg gaagctttag tagaacattc aactgaaaaa
    39481 atagataaga catataggcg agagagatta atcaatgatt tacagaaagc tattttaaat
    39541 tatttactta aactttcaaa agcaccttta gatgatgatt caagagaagt tgtggatact
    39601 ttgtttaata cagtcaatga tatagaaaga attggtgacc acgctaaaaa tatagctgaa
    39661 ttatcgcaag ttgcaataga ttcaaatatt tctttctcag aagaaggaca atctgaactt
    39721 gatgttatgt ataatagagt tgtttcagca tatacttatg cattagaatc aatgagaact
    39781 gataatgttg atttagcttg taaggttata aaaattgaag aacaagttga tataatggag
    39841 aaatcttgta gagctaatca catgtataga ttgaacaata atctatgtag tatagaaaat
    39901 ggagttattt atttagacgt aataagtaat ttagagagaa tatctgacca tgctgtcaat
    39961 atagcacaac aagttatagc aaagagatta ggaaatgatt aaaaataatt aatttaaaat
    40021 aatataaaat ttaaaataga ggataaataa aagagaaact ttaaatgata cgtttagagt
    40081 ttcttttttt gtaaatttat ttgactaaaa tttttaaatt tatacatagt tatagcattt
    40141 agaagaatcg atttcctgat aataaatgat gagatatgta tgattttgtg gcaaactttt
    40201 aaaaaaaaca cctatatttt gtgttataat ctctttaaaa cgaatatgct gaaaagaggg
    40261 atttaaatgg gaaaaataaa ttttgattat agtaaagcta cagagttttt ttgtcaaaac
    40321 gaaatagatg tcatgcaacc atatgtagat gttgcgcacg acatgttaca taataaaact
    40381 ggtttaggaa atactttttt aggatggata gaccttccta aaaattatga taaagaagag
    40441 tttgacagaa taaaaaaatc tgctgataag ataaaatcag actcagatgt tcttttggta
    40501 ataggtatag gaggctctta tttaggttcg agagctgcta tagatatggt aagtcattct
    40561 tttaggaatg gacttaaaaa agagcaaaga aaggctccag aagtatattt tgtagggcat
    40621 aatataagct caacatatat tatggattta ttagatataa ttgaaggaaa ggatatttct
    40681 gtaaatgtaa tatctaaatc aggaactact acagaaccag ctctggcttt tagaatattt
    40741 aaagattact tagagaaaaa gtatggtaag gaagaagcaa gaaagagaat ttatgcaaca
    40801 acagatgcaa gtaaaggtgc acttagacag ttagctacag aagaaggata tgagactttt
    40861 gtaataccag atgatgtagg tggtcgtttt tctgtattga cagcagttgg gttacttcct
    40921 attgctgctg ctggacttga tattgatgct atgatgaaag gcgcaaatga tgctagagaa
    40981 gcatttcaaa atcctgactt aaaaagtaat gatagttata gatatgctgt tgctagaaca
    41041 attttacata gaaaaggaaa agatgtagag ttattagtga actatgaacc tcaactacat
    41101 tatgtaagtg agtggtggaa acagctttat ggagaaagtg aaggaaaaga aaataaaggt
    41161 ttattccctg cttctgtaga tttctcaaca gatttacatt ctatgggtca atacatacaa
    41221 gatggaaaaa ggcttttatt tgagacagta cttaatgttg aaaactgtaa gagaaatata
    41281 actataagtt cagaggaagt agacttagat ggtttaaact atttagcagg taagactgta
    41341 gattttgtaa atcataaagc ttttgaagga actctattgg ctcatacaga tggaaaagta
    41401 cctaatttag taataaatat acctcaacta gatgagtata attttggata tttagtttat
    41461 ttctttgaga aggcttgtgg aataagtgga tatttattgg gagttaatcc atttgaccaa
    41521 ccaggagtag aagcttacaa gaaaaatatg tttgctttac taggcaaacc aggttatgaa
    41581 aaagaaaagg aagagctaga aaaaagactt aaataatttt aaatagttaa ggtttaatta
    41641 agattaaaat aatataatga aatcatcgaa aaggagttta ctcaaaatag atgatttcat
    41701 tttttttatg aaaaattggg aaaaatatat tttgataatt tatattatat taagataggg
    41761 agtggtatga gatgtcaaga agaaagaaag ggataagttt agtaatatta gttgctataa
    41821 taagttcaat acttagtagt tttctaacaa taattttagt taaggacaat ttagtaagta
    41881 aatctacagg aagttctacg ccgatagttg taaatgatga tggtaagagt caaaatattt
    41941 atcaagcagt tgcagaaaaa gctacgccat ctgttgtagg tattacaaca actagtgttg
    42001 atactagtaa tatgtttgca ataccaactg aaacacaagg tgtaggaact ggaatcatag
    42061 ttgattcaaa tggatatata cttactaatt ctcatgttat atcagatggt caagctacaa
    42121 gtgtaaatgt attattcaat gatggttcaa caacttcagg taaagtagta tggtttgacc
    42181 aacaacttga tttagctata gttaaggttg ataaaactgg actaacacca gcagaatttg
    42241 ctgatagtga caaagtaaaa gttggagata tatcaatagc aataggtaat cctcttggat
    42301 tagattttca aaaaacagtt actcaaggga taataagtgg attagataga actatacaaa
    42361 cagaaaaaac taatatgact ggtttattac aaactgatgc aagtataaat gcaggaaata
    42421 gtggaggacc attgttaaat caaaaaggtc aagtaattgg tataaacaca gcaaaagctt
    42481 ctcaagcaga aggattagga tttgcaatac caatcaatac agctaagagt atagttgaag
    42541 aagtaatcaa aaatggaaaa tatgaaaaag taactttagg cataaaaggt acagatgtat
    42601 caaattatga agcagcaaca ggtacaaaat taagtactga taaaggtgtt tatgttgcag
    42661 aagtaatatc tggttcatca gcagaaaaag ctggagtaaa ggtaggggat attataacta
    42721 aagtaggaga tacagatata acaggtatga atgatttaaa taaaaagttg tatactttct
    42781 caaaaggtgc tagtacaaaa ataacagtaa atagaggcgg aaaagcagta acaataaatg
    42841 tgaatttcta aatatgacca gaaagataga gactacatgg taaagtgtag tctctatttt
    42901 tatttaattt ttatagtata tacatctaaa ttaattaaaa tgatgtattg tttatagttt
    42961 attgctatat tttcttataa aaataaattt aataaatatt taaatttaat ttacaaaaac
    43021 aatataaata tcataataaa ataaaatttt ttaatattac taaaaatata tagacaaaat
    43081 aataacgaat atagtattat gtaattgtag aaatgctttt cataggtata ttctatgaag
    43141 atgaattgca taaaaatgaa aaaatggaat ggatattatt taggggtgaa aaatcatgaa
    43201 tccattagtt ataaacttac aaaaatgtag catacatgat ggaccaggga taagaagtac
    43261 agtatttttt aaagggtgtc cacttgaatg tgtttggtgt cataatccag agagtcaaac
    43321 atatacaaaa caagttttgt ataatgaaga aagatgttca aaatgtgaag catgtataaa
    43381 tatatgccct cataaggcaa tttacaaagg tgaaacaaaa atatgcttag accaagataa
    43441 gtgtgagttt tgtgaaactt gcttagacta ttgtgtaaac aatgcaagag agattgttgg
    43501 tcaagagtat tctgtaagag atttggttaa agagatagag aaggatagaa ttttctatga
    43561 agaatcaggt ggtggagtaa ctctatcagg tggagaagta atggctcaag atatggactt
    43621 catttgtgga gtaataaaca tgtgcaaatc aaagggaatc catgtagcaa ttgatacatg
    43681 tggctatgca aagtcagaaa attatgaaag agttgctaaa tgtgcagatt tgtttttata
    43741 tgatattaag cttattgatg aagataagca cataaaattt acaggaaaat caaatgactt
    43801 aatactgaaa aatgttaaga ttttaagtga attaggggct aacataaata taagaatacc
    43861 attaattgta ggagtaaatg tagatgatga aaatttagag gttaaaaaaa tgatagagtt
    43921 tttaaagcct ttgaatatac aagcagtaag tcttcttcca tatcataata ttggtaaaca
    43981 caagtatgat aaaatttata aaaagtatga aggagaagaa ctacaaagac catcagaaga
    44041 aaaattagag gaaataaaaa gactgtttga agcaagtaat ttcaatacta agattggagg
    44101 gtaataaaat ggcaagagga acttttgaga gaactaaaaa attaagagaa gaaagtatta
    44161 atgcagaacc acacatatct attgaaagag cagtacttat gacagaagct tataaaaaat
    44221 atgagggaag tgtagagatt cctgtacttc gtgctttatc atttaagcat tatattgaga
    44281 atagaactct tagcataaat gatggagaat taatagtagg tgaaaaaggt gattctccta
    44341 atggagcacc aacatatcca gaaatttgtt gtcatacaat ggaagattta gaagtaatgc
    44401 acaatagaga tataataaat tttagcgtat cagaagaagc tagaaaaata cataaagaag
    44461 aaataattcc tttttggaaa aagagacaaa caagagataa gataataaat gcaatgacac
    44521 ctgagtggtt agcagcatat gaagcaggta tgtttacaga gtttatggaa caaagagctc
    44581 caggacatac agtttgtgga gatacaatat ataaaaaagg atttttagat ttaaagaaag
    44641 acatagaagc aagattaaaa gagctagatt ttcttaatga tttagatgca tataataaaa
    44701 aagcagattt agaagctatg gcaatagctt gtgatgcaat ggttatatta ggtaaaagat
    44761 atgctgagaa agcaagacaa atggcagaag aagaaacaga tgaagctaag aaaaaagatt
    44821 tattactaat tgctgaaact tgtgatgttg taccagctca caaaccagaa acttatcatc
    44881 aagctataca aatgtattgg tttgttcata taggggttac tactgaactt aatatatggg
    44941 atgcttttac tccaggaaga cttgaccaac atctaaatcc tttctatgaa agagatgtag
    45001 aaaatggaat actagataga gatagagcac aagaattact tgaatgttta tgggttaaat
    45061 ttaacaatca gccagcacca ccaaaagttg gtataacatt aaaagaaagt agcacatata
    45121 cagattttgc aaatataaac actggtggaa taaatccaga tggtcaagat ggtgttaatg
    45181 aagttagtta tataatactt gatgttatgg atgaaatgaa attgatacaa cctagttcaa
    45241 atgttcaaat aagtaaaaag actcctcaaa aattcttaaa gagagcttgt gaaatatcaa
    45301 gaaaaggatg gggtcaacca gcattttata atactgaagc aatagttcaa gagcttatgg
    45361 aagctggaaa aactatagaa gatgcaagac ttggtggaac cagtggttgt gttgaaactg
    45421 gatgttttgg taaagaagca tatgttctaa ctggatatat gaacattcca aaaatacttg
    45481 aattaacatt aaataatgga tatgacccaa ttagtaaaaa acaaataggt attgaaactg
    45541 gagaccctag aaatttccaa tcttatgagg aactatttga agcatttaaa aagcaattac
    45601 attatatgat tgacataaaa atagaaggaa atgctgtgat agaaaatata tgtgcaaaac
    45661 acatgccttg tccacttatg tctacaatag ttgatgattg tatagaaaaa ggcaaggatt
    45721 accaaagagg tggagcaaga tacaacacta gatatataca aggtgttggt ataggaacta
    45781 taacagatag tttaacagca ataaaatata atgtatttga taagaaaaaa ttcgatatgg
    45841 atacattgct taaagcactt gatgctaatt ttgaaggata tgaagctata cttaatttag
    45901 tttcaaataa gactcctaaa tatggaaatg atgatgatta tgctgatgaa ataatgcaag
    45961 agatattcaa tgcatattac aatgaggtaa ctggtagacc aactgtttgt ggtggagaat
    46021 acagagtaga tatgttacca acaacttgtc atatatactt tggagaaatt atgggagcaa
    46081 gtccaaatgg tagactttgt gcaaaaccag tttcagaggg aatttcacct gaaaaaggtg
    46141 gagatactaa tggacctaca gcagttataa aatcttgtgc taagatggac cacataaaaa
    46201 ctggtggaac attattaaat caaagatttg caccatcagt agttcaagga gaaaaagggt
    46261 tagataatat ggctaatcta gtaagagcat actttaatat ggatggtcat catatacaat
    46321 ttaatgtatt tgataaaaat gtactgttag aggctcaaaa gaatcctcag gattataaag
    46381 acttaatagt tagagttgca ggatatagtg accatttcaa taatttaagt agaacactac
    46441 aagatgagat aataggaaga actgagcaaa cattctaggt ttgcttgtaa ataaaacttc
    46501 ttactatata aaatcgtaac tgatataata aagtataaat ggtttgattc catttttaaa
    46561 attttagatt aattatgagc taactttcta aataggaagt tagctcgtta agtttaatga
    46621 aaaaatcgtt aaatttatat ttagtaaatc atacacatat tagtaagtaa tacatacaaa
    46681 agaataattt attatagtta taataaggtt atattttata aaaataagat aattttaagc
    46741 agttaaaata aagtcaattt agctacttta aaataaaact aatagaaaaa aggagatttg
    46801 atatgaaaac tttaggattt attggttcag ggaatatggg aagtgcaatg ataggtggca
    46861 tagtacagtc aggattagta aaggcagaag atataactgt atcagattta agccaagttg
    46921 ccttagataa agtaaaagaa aaatttggag taaatactac aactgattca aaggtagctg
    46981 ttacaaattc tgatgtggta atagtagcac ttaaacctaa tatatgcgaa aaggctttaa
    47041 ctccacttaa agaattaata gatgcaaata aaataatagt atctatagca gcaggtaaaa
    47101 ctatagaaag tctggaaagt tttataggtt cagataaaaa aatagtaaga gtaatgccta
    47161 atactccagc ccttgttggc gaaggaatgt cagctctttg taaaaatagt aatgtaacag
    47221 atgaagagtt aaatatgatt aaggctctgt ttgaatcttt tggtgaggca gaaatagtat
    47281 cagaatattt aatggataca gttacaggta ttagtggttc ttctcctgca tatgtattta
    47341 tgtttataga agctatggca gatgcagcag tattagctgg aatgccaaga caacaagctt
    47401 ataaatttgc atctcaagca gtaatggggt cagctaagat ggttcttgaa actggaaaac
    47461 atccaggtga attaaaagat atggtttgtt ctccagcagg aactactata gaagctgtta
    47521 aggtattaga agaagaaggc tttagagcag cagttataaa atctattgtt gcttgtatag
    47581 ataagtctaa agatatgagc aaataacaga tgtaattaag tttactatat ggtttcttga
    47641 attgtttttt tagtgcttat ttatatctat acataaatgt atttggtata agtaaaataa
    47701 gagtaattta ctataaaaag gaatttaatg attgagtgat aatttattac ttaaatatta
    47761 ataattaaat agatatattt ttaactatat ttgagatata tcattgtgaa aaaataaaat
    47821 ttataagtat tattgtgagg ttataagtag atttatttaa aaataaattt atttatagcc
    47881 tttttaaatt tgaaataata ttcataaggt aataaaagtt acaaatattt tcttcgctaa
    47941 taagttttaa aatacctata atgttttact ttttattata ataaatacaa taaatatatt
    48001 cttatataaa ttctatgtca gatatatgga aagataagaa ccttgagatt atgttaaaaa
    48061 atctagattt tatacttata aaaagtttga ttttacaaac ttacaaaaga gaatcaagat
    48121 aggaatataa ttatcttttt cataaatata taaatgatat actaatatta tagtattatt
    48181 gatatttgta ttggaggttg aacatgaggg atgaaatttt aagttttgta aatgaatgtg
    48241 tattatttaa caactttgat gaacttaaaa aagaaagtgg cataataaca gaagatatag
    48301 taaaaaagtt taatttaagt agaactcaat caagtagatt attaaatgat ttagtaaaat
    48361 ctgataatct tataaagata aacagtagac ctgttatttt tttacctaaa aataaaataa
    48421 atgatgtagt aggacctaca aaaaaaagta tttatgaaaa tttagatgaa cttaaaaatg
    48481 agtgtaaatt attaaagcaa gagactgtgt ttaatagtat cataggatat gataatagct
    48541 taaaagaagt aatcgaacaa ataaaaaccg ctgtacttta tccaaatggc ggacttacaa
    48601 taatgctgac aggtgaaagt ggagtaggaa aaactttttt agccaagata atatacaaat
    48661 atagtgtaag cagtaatgta ttagaaaaaa attctccata caatgtgtta aactgtgcgc
    48721 agtattataa taatttggag ttattgtcta gtctattatt tgggcatgta aaaggagcat
    48781 atactggagc aaatgaatct agagcaggtc taatagaaca atcagatggt ggtgttttat
    48841 ttttagatga agtacataga ttaaatagtg aaggtcagga aaagttattt acatttatgg
    48901 atacaggtac gttttctagg attggagaga atggagtaat tagaaaagct agggtaagat
    48961 taatatttgc tacaacagaa agtctatctg aatttttaca aaccttttta agaagaatac
    49021 ccataaatat ttatgttccc aatatagaag aaagagggac tattgaaaaa agaaagattg
    49081 tagaacattt tatttatgaa gaaagtaagg tacttggttt gcctatagag ataactcaaa
    49141 ttacattaaa tgcgatttta aagataaaat tcaaggggaa tataggtgaa tgtaaaaatg
    49201 taataaaata tgcatgtgga cgagcttatg caaaaaatca aagaagaaat ggaaatattt
    49261 ttgttactct tcaagacctt cctagaaatc tttatataga aaatgtagat atatttcaat
    49321 tccaaagtgg taaaagcaaa agcattatct tttctcctaa acaatttagt attgaaatgt
    49381 caaatggaag aaataaaaga aatataatct atcaaagttt cataaaatgt ttagattact
    49441 ttgatagact agaaaaaaat gaaataacaa aggaaaaatt tagtaaaaag agttctaatc
    49501 taatgattag actaatggac aatttagtct tttcaaataa tgatgaaaat aataacgtac
    49561 ttatggagct tataatatcg ataatgcagg atatatttag aaatttagaa gttaataaca
    49621 atataaaata tgatgggaat aatgtattgg cattttcgtc ttatctttat ttgaaggacg
    49681 aatcttatca attgtctgat gagtataaag ctttagaaaa taaattacta atatatttaa
    49741 aaaaagagag ttacaaagaa tactctataa taagtaaaat atcaacatta ataacgaata
    49801 gattggatat gtatcttaat aatgtagata taatcataat gattatattt attaaatcaa
    49861 caattataag aatgaaattt aatcaagtta atgcgactat tatagcacat ggatatgcta
    49921 ctgccagtag tatggcgaat gtatgtaatc ggatgttggg taaaaatata tttacagcta
    49981 ttgatatgcc tatagatgct actattgcgg atgtatcaaa acaaatgtct agatacctag
    50041 agggagatag gataaagaat ggtttaattg tgttatttga tatgggctct cttaatctta
    50101 tatatgaaga tttaaagaat aagataaata gcccaatgtt atttatagac caaatatcca
    50161 ctatttctgc actagaagta ggaaatttat taatgcaagg taaaaacatt gaagagattg
    50221 cagaaattat ggatgaagaa actaaaccta atatacaatt gtattatcct caaaaaaata
    50281 aagaatatgc tataatatca tcttgtttta cagggatagg tactgctata aaaatccaac
    50341 atctactttc cgaaagttta attggaatag ttgatgtcaa aataatacct tatgattatg
    50401 atagtcttgt ttctatggga gataaagaac cagtttttga aatgtatgat gtgatggcta
    50461 tagtaggaac tgccaatcca aatgtgaatg gggtagattt tatattatta gaggatataa
    50521 tatcaggaaa aggagaagat gatgttttta gaatatttag cagagtagta gaaaatgaaa
    50581 aaataaagaa cataaatgat tctattgtaa agaatttttc attaattaga gtaatagata
    50641 gtctaactat tttagattca aaaaagataa tagagagaat agaagaagga attaatgcta
    50701 tagaaaatat tcaaaagaaa aaactttcaa atgataaaaa gatttcttta tatgttcact
    50761 taagttgtat gattgaaaga ttagttagac aaactgaaat tgaagagtat actgatatgg
    50821 atttgttaat caaaaaccat catagtgaag taaaactaat aaaaaatgca tttagtgtgc
    50881 tagaaaagag ttatagtgtg caaataccaa tttcagagat aggatatatt tataatatta
    50941 tctatggtct accacagtaa aatacaagat tacaaaataa gtgaatgaaa tttaaaaaag
    51001 tatgccagta tttggcatac tttttgcttt tatagataaa tgagagtata aacaataaaa
    51061 attttaatgt atgatggagg atttggggaa aatggtatct ttgatgagaa ttgatgacag
    51121 attgatacat ggtcaggttg catatggatg ggcaacatca ctaggtataa atgtaatact
    51181 agttgcaaat gatgaagcaa aaaatgacca aatgaaagct atgtcactga acttagcgaa
    51241 acctagcaat gtaactttat atataagggg ggtagaggaa tctggagaaa tagtagaaaa
    51301 atttgcttct tcaaagaaaa gcaatgtatt agtgttagta aaaaatacca aagatgcttt
    51361 agttgtagct aaaaattcag gaggagtatt aaaagaaata aatgtaggag gattaagata
    51421 tgaggaaggg aagaagaaac ttacagattt agttgctgtt gatgatgatg atataaataa
    51481 ctttaaacaa ataggtgatt tagggattga tatagaattt agaatgttac ctagagacaa
    51541 aaagaaacaa ctatcagatt taataaaata atttaggaga aagagaatga aaaaatttct
    51601 aattgcaaca catggagaat tgtccagaga gcttgttgac acaagtaaat taataattgg
    51661 ttcattaact aatattgagt atttttgtat gacaacggat aaatcagcag atgatgctga
    51721 gaaagaaatt agaagtatat tatcaaataa taaagatagt gaagaatttg ttgtcttaac
    51781 agatgttttt ggtggaagtg tggcaaacat atgtacaaac ttacttttac aagggttcaa
    51841 atttgaatta ttgacaggag taaatttacc aatgctttta tctatacttt tattagttga
    51901 ggaggataca aaactaatag ttaaatcagg attagaggaa gcaaaaaatg gaattgttta
    51961 tgtaaatgag ttattagaaa atcaaaacaa aatcaaaaat gtaatgtaat ttaatgtaaa
    52021 ttaaactaag ttaaaatgga ggttcaatat gttagtacaa gctactatgt tagctattat
    52081 agcaggagtt ggtatactag atgggcgtat atttggtcaa tctatgcttg ataggccaat
    52141 agttacaggt atgttagtag gattagtttt aggagacata aaatcaggaa ttatgattgg
    52201 tgcacagctt gaattaattt ggatgggaat tgcaggaata ggtgcagcta ctcctccaga
    52261 tgtagtaaca ggaggtgtat taggtacagc ttttgctata ttatcaggta atggtgcaga
    52321 agttgcttta gcagtagcag taccagtagc agtcttagca caatctcttg gagtattagt
    52381 tagaataata aattcgtact tttctcaaaa ggcagttttc tatgctaaac aagctgattt
    52441 taagaaagtt accataatga tgtggttgcc agtaatatta ttctttttaa gtacatcagt
    52501 tccaaccttt ttagcaatta tgattggtgc tgataaagtt acagcattga taaatgcaat
    52561 acctaaagtt atattagacg gactgggtgt tgcaggaaca ttgttgccag cagtaggttt
    52621 tgcattgctt atggatatgt tactttcaaa aaagatgtct gtatttttct ttatagggtt
    52681 tttgttagca tcttatggtg gattagatat aactgctata gctttatttg gagtatgtgt
    52741 agcatttgta ctaaactttt atatcaataa caaagaaaat aatcaaaatc ctcaattagc
    52801 aatcaatact ttaacggaag gagagattga ctttgaataa attaacaaaa aaagaattaa
    52861 gaagtatgtt ttggcgttca tttgctcttc aaggtgcatt taattacgaa agaatgcaaa
    52921 acttaggtta ctgttattca atgttacctg caataaagaa gctatacaat aagaaagaaa
    52981 atcaagcaaa agcaatagaa aggcatttgg agatttttaa tacaacgaca gtagtagttc
    53041 ctgctatatt aggtataaca gcagctatgg aagaagagaa tgctaataat ccagaatttg
    53101 atgaaagttc aattagtgct gttaaaacag ctcttatggg acctcttgca ggaattggtg
    53161 attcattatt ctggggaaca tttaggatta tagcagcagg agtaggagta tcacttgcaa
    53221 aagaaggtaa tatctttgga ccactattat tcttactatt atacaatata ccagcatttg
    53281 cccttagaat atttggactt aagtatggtt atcaagtagg ggtaaattct cttgaaagaa
    53341 tacaaagaga gggacttatg gagaaaataa tgtctatggc tacaactgtt ggtttattcg
    53401 ttgtaggagg aatggttgca actatgttga gtataactac tcctctgaaa ttcaacttaa
    53461 atggtgcaga agtaatttta caagatatac tagataaaat aatacctaat atgttacctt
    53521 taacctttgc atttgtaata tactacatgt taaagagaaa ggtaagtgta acaaaattaa
    53581 ctataggcac tatagtaaca ggaatcgctt tacatgctat aggtttgtta tagaaattaa
    53641 ttataattta ttgaatatat agataaggaa ggtgtataaa atgacaatac aagattatat
    53701 gttagaaaca ccagttagaa tgagagaaat tatatctaat gcagatagct tatttaatga
    53761 agttaagaga acaaatctaa aaaagattat aataacaggt tcaggtacta gctatcactc
    53821 aggagtgcaa gtacaaccat atttacaaaa tttattagat atagatgttg tgaaaatgta
    53881 tccatttatg ataactgaag atacattcaa gtttgataat gaaaataccc tagtagtagg
    53941 tgtatctcaa ggtgggagta gttattctac atacaacgct atgaagttag ctgaagataa
    54001 gggctgtaaa atagcatcta tggcaggttg taagaatgct ttaatagatg agatttctga
    54061 ttatatatta acagtaaatt gtggtgaaga aaaatctgga gctaaaacaa aaggatatta
    54121 ttgtacaaag ttaaacttaa tgttattagg tcttcaaata gctagagaaa aaggtataat
    54181 atctagtgaa aagtacaatg aggaaataaa taagatatta gacgcaatta atagatttga
    54241 agcagtgtat aagctctcta aacaatggat tgaaagaaac aaagaaaagt tagttaattc
    54301 taaagaaata agaataatag gtcactctga tatatatgga gatacattag aagcagcatt
    54361 aaaattattg gaaacaatga gaatacctgt aactgggtat gagtttgaag agtttataca
    54421 tggtatatat aatgctataa atagtgattc tactatattt atactagata caggaaaaga
    54481 acctagagta actaagatga ttgatgtact ttctggttgg acggaaaatg tatttgctat
    54541 aggtagagat gttacagaaa atgataaaaa tttaaagatt gatatcacag ataatcctta
    54601 ctatcaaaca tttaatttta tagtacctat acaactaata tgtggggaaa tacctacatt
    54661 aagaggtgta gacccaagtg ttccaaaaga tactaggttc cacatgaagt taggtagcaa
    54721 gaaactgaat aagtaacaaa aaaagaggtt gtctcaaaat agagataagc ctctttttta
    54781 ctagataagc tcttttttac tgttgaaatg atgaaaatat atttgatttt ctataaaaaa
    54841 gagtgcctca tgaactaaaa agttaatttt gagacaccca cttttatctt attttaaact
    54901 aaaatattta tatattagtg tgcattattt tttttattgc tgtcttcctt acttgagcaa
    54961 gaattagcac ttggacatcc agaacaaata gaacatccac tacagacatt tccgtttttt
    55021 gtagacttga atttattaaa cagaataaag agtgcaagga ctataattat tccacctatc
    55081 aaagcttcta ttattgaatt acccataaat agtactccac ctatactttt aactataaaa
    55141 gccattatcc atgctagtat aaattgatat gcaaatgatg taaacatcat tttattgcca
    55201 tattcttttt tcatagttgc aagtgcagct atacatggag tatataaagc agtaaatatc
    55261 aagaatgtat atgcagtaac tccattaaat attgttggta agacaacagt tagattacca
    55321 tatagtatat ttaaagagtt tactacgatt tcttttgctc caagaccact taaaatagca
    55381 actgaagttc tccaatcatc aaaaccaaga ggtttgaata taggagatat aatatgacct
    55441 agagtagcca agaagcttac atttatatct tctgtatatc caaaaacatt gaatgaagaa
    55501 agtccccaaa ttacgactga cattgcaaac atgacagtaa caactcttat caagaaacct
    55561 tttgatttat tccaagtatt tttaataagt gcatctatag tagggattct atattctggt
    55621 aattctaata taaatggttc agcctctgtt ttaaaggctg ttttatttaa gaataatgca
    55681 actacaattg ccataactat acccaccaaa tacagtgatg tagttactaa agcagcatta
    55741 tgtggaaaga atatagctac aaatagtgca tatataggta gctttgctcc acaagtcata
    55801 agtggtgcaa taagagctgt aactcttcta tctttttcgc tttccaatgt tctagttgcc
    55861 attatagctg gagaagaaca tcccataccc ataactatag gtataaaagc tttaccagat
    55921 agaccaacct ttctcataac tttatccatt aaaaatgctg ttcttgacat atatccacta
    55981 tcttcaaaca acgatatacc aaagaataat gtaaatatta aagggaagaa tggtaaagta
    56041 ccaccaacac ctccaattat tccatcaact ataagtgatt taaaccatgg gctagagtta
    56101 gataacatat cactaacagg tgcagaaata taagcctcta taagactagc aaatccctct
    56161 tgtagtggtc ctccgaccca gtcaaaggta aatttaaata agaggaacaa tacaccaata
    56221 aatatcggat atgctaatat aggattcaag actatattgt ctatcttatc actgatagat
    56281 ttcttttgtg tatatgtagt ttttgtacat ctcgataaaa tggattctaa ttttttatat
    56341 gtttctgttt cacttccaaa gtttttctga tatataaaag ctttttgcgt agctccctta
    56401 atctcttctt ctatcctatc aacaccattt ttcttttttg ctataattgg aacaacaatt
    56461 actccaagtt cttcacttaa ttttttggca tctatattaa ctcctttaga ttctgcaatg
    56521 tctaacatat taagcaatat aactataggc ttgttaaatt gcataagttg agttgttaag
    56581 taaaggtttc ttgataaatt agaagcatca actacattta ctattacatc aacatcttca
    56641 ttttctaaat atgatttaga aaccttttct tcatttgaga aagtatccat tgcatatata
    56701 ccaggtaaat cgacaacctt tatctctttt ccaagaaatc cttctttttt ttctatagta
    56761 acaccaggcc agttacctac atattgattt gaacctgtaa gtagattaaa aacagtagtt
    56821 ttaccgacat ttgggtttcc taataatgct acattaatca cgggtagctc ctcctctatt
    56881 attgtaaaga aatattttta gcatcagatt ttctaatcgc aaggtcaaag cctctaaatc
    56941 taattataat tgggtctcca agtggggcaa cctttttaac ttctatttca gtactattta
    57001 tacatccaag tgcaagcaat cttttagata atttaatatc tccatctata ctattaataa
    57061 atcctttttc tcctattttt aaatcgtaaa cagtcattat taacacctcc taatgaaatt
    57121 cattatcatt aaaattgtaa caagtatgat acaaaaagtc aagatttata gaggtaattg
    57181 cacattgaaa taactaatat ttattctaaa tagattaaaa atattttagt ctaaattagg
    57241 tgtttttata tattttgtat tataatgtaa gatgatagat aaaatttgga ggagttaact
    57301 taatgaaaac tagaaaaatg acatttttag gtcttatgat agggtatagt ttagctttat
    57361 atgtattaga gacatatata ccaaatcctc ttatagttat atttccaggg gcaaaattgg
    57421 gtttgagcaa tattataact ttaatttcat taatgttgtt aggtgtcaaa gatactgtta
    57481 taattgttac tatcagggta attttgtcat caatatttgc aggcccttta tcatatctac
    57541 tatttagtat aggaggagct tatctgagtc ttttatttat gtatttagcg agtaaaataa
    57601 aagatttatc actaataggg ataagcatta taggtgcaat agggcataat ataggtcaat
    57661 taatagttgc aagtttaatc atagaaaata tacttgctat agggtactta ccatttatgt
    57721 taatggcatc attagtaact ggtatgtttg taggcttagt atccaggtat acaataccta
    57781 aattaaagca tttttatagt aagttttatt gacataatat tgacaaaata taatattgtt
    57841 tgataaaatg tatataaaaa tatacaaatt tgtaatagtg gtgattatta tggcgaacaa
    57901 tgaattagaa gcgttaaaaa atgagattga agcagttagg gaagagataa atacatacat
    57961 agaatatcca gaaatatttc aagaagagtt agtagaatca agtaagaaaa tagatatatt
    58021 aataaataaa tacatgtacc taagcaaata gcccacagtt gtgggttttt ttgtatcaaa
    58081 aattaacaga tggctatatt ttacatatat taataataat attaagatat aaaatagtat
    58141 ttctgatgtg taaattatct gtaggacata agttgtaatt aagtcaggag ggttttatat
    58201 tatgattgat ataggaagta aggagatagc aataaggtta ctattagcac taataatagg
    58261 aggaataata ggcttagaga gagaaaaaat aagacagttt gcaggattta ggacacatat
    58321 actaattgca ataggttctt gtattgtttc aataacttcg attcaattat tctttgatta
    58381 taatttgtat acaaatgctg acccagcaag aatgcctgct caagtattat ctggaattgg
    58441 ttttttaggt gcaggagcaa ttttaaaaaa taaaggtgga gtaaaagggc ttactacagc
    58501 tgctgggatg tgggcaactg catgtattgg tatagcagtt ggatatggtt attatgaatt
    58561 ggcaattcta ggtggattat ttgtaatgat agcattattt gtgcttagga taatcaatac
    58621 gtttttattt agccaagaaa agaatgtatt gatattaaaa ttaagcaatt tggattctat
    58681 acctttttta tatgataaat ttgaaaaaaa tcaacttatc gtaagaaata tggaaataga
    58741 atgtcgtaat gaagaatact ggaaggttaa tttttttgta tcttatgcta agagaataca
    58801 cttacacgac gttatgaaag aaataaatat gatagaagga gtaataaatg tagattattt
    58861 ggactaaaat atatacaata tattttgtaa agtgaataaa atataaaaca aattaaaata
    58921 gaggtgtatg atatgggaac tgatagaagt acaatagaag aaaagtacaa atggaagata
    58981 gataagatgt actccagtaa agaggaaatt gaaaaagaca taagtaaagt aaaaaatctt
    59041 atccaagaag taaaagaata taaagggaag ctttctgaga gtaaggagaa cttatataaa
    59101 gtattaaata tctctgaaaa tgcatctagg attgttcaaa atttatatgt atatactcat
    59161 atgaaacaac atgaagatac tagaattaat gataatcaag gaagagccac taagacagaa
    59221 atgttatcta ctgatttagg tgtggctact tcttatatag ttccagaaat actggcgata
    59281 gaagagaata agttaagtga atacttaaaa gatgagaagc tatcctttta tgcaaaatat
    59341 ataaaggata tattgagaga taaaccacat actttgagtg aacgagagga agaaatactt
    59401 gcagctacat cagaattatc gacaattcca gaaaatgtat acgatatgtt agcatatgca
    59461 gatatggaat ttcctgagat agaagatgag gaggggaata aggttaagct ttctcattca
    59521 aactactctt tatttataaa aagtaagaat agtagagtta gaaaagacgc ttttgaaggt
    59581 gaattttcaa catatgagaa atataaaaat acatttgcct caacgcttta tggtggaata
    59641 aaatcagaga tattttacgc aaaaactaga aagtataatt cagcaataga agcgtcttta
    59701 ttttcagatg atgtaagttt agatgtttac aataatctta tatcagctat agataaaagt
    59761 attcctaatc taaataaata tgttgagctt aaaaagaaat ttttaggatt gaatgaaata
    59821 cacatgtatg atttgtatgt tcctttgaca gataaatttg acatggatat accatatgat
    59881 aaagcacagg atatcatatt agaggcactt aaacctttag gagaagaata cttgaaggtc
    59941 ataaaaagtg cttttgatga agggtggatt gatgtatatg ataatgaagg taaaaaagga
    60001 ggagcttatt cttggggaag ttatgattca catccttata tattaatgag ctataaaaat
    60061 gaccttaatt ctctattcac tttaattcat gaattagggc actctgttca cagtcattat
    60121 tcaagaacaa gtcaaccatt tttatattcg gactataaga tattcgttgc agaagttgca
    60181 tctacattaa atgaattact tcttataaat tatttattag aaaattctaa gtctaaggat
    60241 gaaactatat acttattaaa ttattattta gaacaattta gaactacagt tcatagacaa
    60301 actatgtttg ctgaatttga aaaaattgta catcaaaggg tagagagtgg agaaccactt
    60361 actgctgatg aatttactaa tatatactac aaattaaatg aaaagtatta cggaaaatct
    60421 gcaatagtag ataaacaaat aggaatagaa tgggcgagaa tacctcattt ttattcaaac
    60481 ttctatgtat ataagtatgc cacagggttt tctgctgcaa gtgctttaag tcaacagata
    60541 ctttcagaag gaagtactgc agtagataga tatataaact tcttaaaaag tggagggtca
    60601 gaatacccac tagaacaatt aaaatctgct ggtgtagata tgacgaaaaa agaatctata
    60661 gaggaagcct taaatgtatt tgctgaatta gttaataaac tagaaaaaga attataggat
    60721 gtgataggtt gatagcttca atgaagactt ctgataatat gagttgtatt atgtttatat
    60781 ctgcctaaag taactttaaa aagttaatct aattaagaat aaatcatata aaattaagtt
    60841 tttacatgta tttaacaata tttacattta cttaaccctg ctctaatatt catttaacaa
    60901 agaatctgta ttattaaaat atagaaaaat gacaacaaaa aattaaaata taagcggggg
    60961 taagtaaaat gtttaaaaag aaaataggcg ttcttttagc tagtacaatg ttagttggag
    61021 ctttagcagt aggatgtagt tctaactcag gaggttcagg tgattcagga gattcaagca
    61081 aagtttctgt ttcaggttca acttcaatag gtcctcttat ggaaactatc ggagaaaagt
    61141 ttcaagaaaa aaatcaaggt gttagtgtag aagtacaaca gattggttct tctggaggta
    61201 taaaaaatgc tatagaagga acatctgaaa taggaatgag ttcaagagat ttaaaagatg
    61261 aagaaaaaag tgctggatta aaggaaacta aaatagcaat agatggtata gcattgataa
    61321 ctaatactgc aaactcagta aaaaatctga caatggacca agttaaaggt atatatacag
    61381 gaaagattac taactggaaa gaagtaggag gaaatgatgc accaatagta atagtatcaa
    61441 gagaagaagg ttcaggaact agagatggat tccaagaaat tgtagggttt gattcagaag
    61501 aactaactaa agatgcacaa ataagtgatg gttcaggaaa tataaaaact acagttgaag
    61561 gaaatgaaaa tgctatagga tatatatcat ttggatatgt tgatgagaaa gtaaatagtt
    61621 taaaaataaa tgatgttgaa gcaactgatg caaatgtaat agctaataaa tatccaatat
    61681 caagaccatt tatattagtt aataaagaag atggtttgtc agaaaaaggt aaagctttaa
    61741 tagattatat attaagtgat gaaggacaag cacttgtttc agaaaaagga tttattaaag
    61801 ttaatcaata acaagagtta taatataaag taaacatata ataccctgtg agataagctc
    61861 ataaaaatga tgctttaact tgcagggtat tgtctattat tgaatgtaga aatataaata
    61921 tctttagata aaataggtat tttagtatct tatctctaag aatatggaaa tattgacaaa
    61981 ataatattac aatgttagaa taaaaaagaa atttatgaaa atatataaaa gatttttaat
    62041 aaaaatattt tagaaactga gaagtatatc ttattattgg gcatctagag atatatggag
    62101 ttagtggtgc aaccggctat gaatataatt tttatattgc atagtctttt tttgttttaa
    62161 aattaacaaa tatgttgcaa aatttgaaaa taagagtatt agtcgttaag atttttattg
    62221 ataggtaaaa ttttggcttt taaagtagcc atttgttgga aaagggaaat tttt
//
LOCUS       DAYAKB010000018        57056 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.018, whole genome shotgun sequence.
ACCESSION   DAYAKB010000018 DAYAKB010000000
VERSION     DAYAKB010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57056
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.018"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            704..1684
                     /locus_tag="ACGI3L_001315"
     CDS             704..1684
                     /locus_tag="ACGI3L_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFG9197040.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
     gene            complement(1783..2745)
                     /locus_tag="ACGI3L_001316"
     CDS             complement(1783..2745)
                     /locus_tag="ACGI3L_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFG9197041.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFAWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(3061..4011)
                     /gene="hpdA"
                     /locus_tag="ACGI3L_001317"
     CDS             complement(3061..4011)
                     /gene="hpdA"
                     /locus_tag="ACGI3L_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HFG9197042.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(4004..4261)
                     /gene="hpdC"
                     /locus_tag="ACGI3L_001318"
     CDS             complement(4004..4261)
                     /gene="hpdC"
                     /locus_tag="ACGI3L_001318"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HFG9197043.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            complement(4265..6973)
                     /gene="hpdB"
                     /locus_tag="ACGI3L_001319"
     CDS             complement(4265..6973)
                     /gene="hpdB"
                     /locus_tag="ACGI3L_001319"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HFG9197044.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            complement(7270..8286)
                     /gene="tsaD"
                     /locus_tag="ACGI3L_001320"
     CDS             complement(7270..8286)
                     /gene="tsaD"
                     /locus_tag="ACGI3L_001320"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFG9197045.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            complement(8292..8768)
                     /gene="rimI"
                     /locus_tag="ACGI3L_001321"
     CDS             complement(8292..8768)
                     /gene="rimI"
                     /locus_tag="ACGI3L_001321"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFG9197046.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            complement(8758..9474)
                     /gene="tsaB"
                     /locus_tag="ACGI3L_001322"
     CDS             complement(8758..9474)
                     /gene="tsaB"
                     /locus_tag="ACGI3L_001322"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFG9197047.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            complement(9474..9926)
                     /gene="tsaE"
                     /locus_tag="ACGI3L_001323"
     CDS             complement(9474..9926)
                     /gene="tsaE"
                     /locus_tag="ACGI3L_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFG9197048.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            complement(10065..11105)
                     /locus_tag="ACGI3L_001324"
     CDS             complement(10065..11105)
                     /locus_tag="ACGI3L_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HFG9197049.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            complement(11434..12039)
                     /locus_tag="ACGI3L_001325"
     CDS             complement(11434..12039)
                     /locus_tag="ACGI3L_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9197050.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     regulatory      complement(12164..12281)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(12341..13507)
                     /locus_tag="ACGI3L_001326"
     CDS             complement(12341..13507)
                     /locus_tag="ACGI3L_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9197051.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     gene            complement(13655..15796)
                     /locus_tag="ACGI3L_001327"
     CDS             complement(13655..15796)
                     /locus_tag="ACGI3L_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFG9197052.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            complement(15940..17047)
                     /gene="prfB"
                     /locus_tag="ACGI3L_001328"
     CDS             complement(join(15940..16971,16973..17047))
                     /gene="prfB"
                     /locus_tag="ACGI3L_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFG9197053.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            complement(17062..19737)
                     /gene="secA"
                     /locus_tag="ACGI3L_001329"
     CDS             complement(17062..19737)
                     /gene="secA"
                     /locus_tag="ACGI3L_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFG9197054.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            complement(19869..20420)
                     /gene="raiA"
                     /locus_tag="ACGI3L_001330"
     CDS             complement(19869..20420)
                     /gene="raiA"
                     /locus_tag="ACGI3L_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFG9197055.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQENYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            complement(20973..21647)
                     /locus_tag="ACGI3L_001331"
     CDS             complement(20973..21647)
                     /locus_tag="ACGI3L_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFG9197056.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            complement(21650..22702)
                     /locus_tag="ACGI3L_001332"
     CDS             complement(21650..22702)
                     /locus_tag="ACGI3L_001332"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HFG9197057.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            complement(22751..23710)
                     /locus_tag="ACGI3L_001333"
     CDS             complement(22751..23710)
                     /locus_tag="ACGI3L_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HFG9197058.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            complement(23803..24324)
                     /locus_tag="ACGI3L_001334"
     CDS             complement(23803..24324)
                     /locus_tag="ACGI3L_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdB-related putative oxidoreductase"
                     /protein_id="HFG9197059.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            complement(24335..25669)
                     /gene="celB"
                     /locus_tag="ACGI3L_001335"
     CDS             complement(24335..25669)
                     /gene="celB"
                     /locus_tag="ACGI3L_001335"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFG9197060.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            complement(25708..26034)
                     /locus_tag="ACGI3L_001336"
     CDS             complement(25708..26034)
                     /locus_tag="ACGI3L_001336"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9197061.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            complement(26058..26366)
                     /locus_tag="ACGI3L_001337"
     CDS             complement(26058..26366)
                     /locus_tag="ACGI3L_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9197062.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            complement(26507..28420)
                     /locus_tag="ACGI3L_001338"
     CDS             complement(26507..28420)
                     /locus_tag="ACGI3L_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9197063.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            complement(28752..29492)
                     /locus_tag="ACGI3L_001339"
     CDS             complement(28752..29492)
                     /locus_tag="ACGI3L_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFG9197064.1"
                     /translation="MINKCLDFIYPENISCIICDKSIKKTNTYSICKSCFKEMNFIQD
                     GCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKT
                     FMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQKIAFNLSKIVNIPLL
                     DCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEI
                     SKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            complement(29537..31756)
                     /locus_tag="ACGI3L_001340"
     CDS             complement(29537..31756)
                     /locus_tag="ACGI3L_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFG9197065.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEENFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            complement(32020..33117)
                     /locus_tag="ACGI3L_001341"
     CDS             complement(32020..33117)
                     /locus_tag="ACGI3L_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197066.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            complement(33432..34625)
                     /gene="metK"
                     /locus_tag="ACGI3L_001342"
     CDS             complement(33432..34625)
                     /gene="metK"
                     /locus_tag="ACGI3L_001342"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFG9197067.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     regulatory      complement(34762..34865)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            35054..35563
                     /gene="yyaC"
                     /locus_tag="ACGI3L_001343"
     CDS             35054..35563
                     /gene="yyaC"
                     /locus_tag="ACGI3L_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HFG9197068.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     gene            complement(35674..36102)
                     /gene="fabZ"
                     /locus_tag="ACGI3L_001344"
     CDS             complement(35674..36102)
                     /gene="fabZ"
                     /locus_tag="ACGI3L_001344"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFG9197069.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNITVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(36118..37137)
                     /locus_tag="ACGI3L_001345"
     CDS             complement(36118..37137)
                     /locus_tag="ACGI3L_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HFG9197070.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            complement(37334..37594)
                     /gene="spoIIID"
                     /locus_tag="ACGI3L_001346"
     CDS             complement(37334..37594)
                     /gene="spoIIID"
                     /locus_tag="ACGI3L_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HFG9197071.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            complement(37692..38360)
                     /locus_tag="ACGI3L_001347"
     CDS             complement(37692..38360)
                     /locus_tag="ACGI3L_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HFG9197072.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            complement(38426..39490)
                     /gene="spoIID"
                     /locus_tag="ACGI3L_001348"
     CDS             complement(38426..39490)
                     /gene="spoIID"
                     /locus_tag="ACGI3L_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HFG9197073.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            complement(39577..40830)
                     /gene="murA"
                     /locus_tag="ACGI3L_001349"
     CDS             complement(39577..40830)
                     /gene="murA"
                     /locus_tag="ACGI3L_001349"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFG9197074.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            complement(40851..41588)
                     /locus_tag="ACGI3L_001350"
     CDS             complement(40851..41588)
                     /locus_tag="ACGI3L_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HFG9197075.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            complement(42058..43353)
                     /locus_tag="ACGI3L_001351"
     CDS             complement(42058..43353)
                     /locus_tag="ACGI3L_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFG9197076.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWREESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            complement(43804..45636)
                     /gene="glmS"
                     /locus_tag="ACGI3L_001352"
     CDS             complement(43804..45636)
                     /gene="glmS"
                     /locus_tag="ACGI3L_001352"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFG9197077.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            complement(45903..47249)
                     /gene="glmM"
                     /locus_tag="ACGI3L_001353"
     CDS             complement(45903..47249)
                     /gene="glmM"
                     /locus_tag="ACGI3L_001353"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFG9197078.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            complement(47419..47976)
                     /locus_tag="ACGI3L_001354"
     CDS             complement(47419..47976)
                     /locus_tag="ACGI3L_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HFG9197079.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            complement(47977..48729)
                     /locus_tag="ACGI3L_001355"
     CDS             complement(47977..48729)
                     /locus_tag="ACGI3L_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HFG9197080.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            complement(48729..49808)
                     /locus_tag="ACGI3L_001356"
     CDS             complement(48729..49808)
                     /locus_tag="ACGI3L_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HFG9197081.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            complement(49837..50052)
                     /locus_tag="ACGI3L_001357"
     CDS             complement(49837..50052)
                     /locus_tag="ACGI3L_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9197082.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            complement(50095..50772)
                     /locus_tag="ACGI3L_001358"
     CDS             complement(50095..50772)
                     /locus_tag="ACGI3L_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9197083.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            complement(50762..51841)
                     /gene="buk"
                     /locus_tag="ACGI3L_001359"
     CDS             complement(50762..51841)
                     /gene="buk"
                     /locus_tag="ACGI3L_001359"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HFG9197084.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLA
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            complement(51863..52765)
                     /gene="ptb"
                     /locus_tag="ACGI3L_001360"
     CDS             complement(51863..52765)
                     /gene="ptb"
                     /locus_tag="ACGI3L_001360"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050182 - phosphate butyryltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019605 - butyrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HFG9197085.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            complement(53069..54250)
                     /locus_tag="ACGI3L_001361"
     CDS             complement(53069..54250)
                     /locus_tag="ACGI3L_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFG9197086.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESMEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            complement(54247..55086)
                     /gene="cdaA"
                     /locus_tag="ACGI3L_001362"
     CDS             complement(54247..55086)
                     /gene="cdaA"
                     /locus_tag="ACGI3L_001362"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFG9197087.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            complement(56070..56143)
                     /locus_tag="ACGI3L_001363"
     tRNA            complement(56070..56143)
                     /locus_tag="ACGI3L_001363"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56107..56109),aa:Arg,seq:tct)
     gene            complement(56153..56227)
                     /locus_tag="ACGI3L_001364"
     tRNA            complement(56153..56227)
                     /locus_tag="ACGI3L_001364"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56193..56195),aa:Gly,seq:gcc)
     gene            complement(56238..56314)
                     /locus_tag="ACGI3L_001365"
     tRNA            complement(56238..56314)
                     /locus_tag="ACGI3L_001365"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56278..56280),aa:Asp,seq:gtc)
     gene            complement(56320..56395)
                     /locus_tag="ACGI3L_001366"
     tRNA            complement(56320..56395)
                     /locus_tag="ACGI3L_001366"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56360..56362),aa:Val,seq:tac)
     gene            complement(56401..56474)
                     /locus_tag="ACGI3L_001367"
     tRNA            complement(56401..56474)
                     /locus_tag="ACGI3L_001367"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56440..56442),aa:Gly,seq:tcc)
     gene            complement(56489..56563)
                     /locus_tag="ACGI3L_001368"
     tRNA            complement(56489..56563)
                     /locus_tag="ACGI3L_001368"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56528..56530),aa:Glu,seq:ttc)
     gene            complement(56571..56646)
                     /locus_tag="ACGI3L_001369"
     tRNA            complement(56571..56646)
                     /locus_tag="ACGI3L_001369"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56611..56613),aa:Met,seq:cat)
     gene            complement(56662..56747)
                     /locus_tag="ACGI3L_001370"
     tRNA            complement(56662..56747)
                     /locus_tag="ACGI3L_001370"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56711..56713),aa:Leu,seq:taa)
     gene            complement(56753..56827)
                     /locus_tag="ACGI3L_001371"
     tRNA            complement(56753..56827)
                     /locus_tag="ACGI3L_001371"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56793..56795),aa:Asn,seq:gtt)
     gene            complement(56835..56951)
                     /gene="rrf"
                     /locus_tag="ACGI3L_001372"
     rRNA            complement(56835..56951)
                     /gene="rrf"
                     /locus_tag="ACGI3L_001372"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        17306 a        10729 c         6127 g        22894 t
ORIGIN      
        1 aattattgat attttattac aaatactata tatattacta ataattatat ttacttttta
       61 ataataaata aaattttaat tttaaataaa tttatttttg atatttatat ttattttttt
      121 gatattaaca ttacaaattc atcctaattt ttataaataa aataataaat taactttcta
      181 ataaattttt tgtattattt tgtatatagg aaattattga aatcataaaa aatcaacgct
      241 atattataat catatagtaa attaaaatca tttgatttat ttaattatta tttattaacc
      301 agacgaatgt aataattatt aaatataaaa tattaaaatc aaagagaata ataaatgtaa
      361 tattaaaact caataataaa tttatattca taagtttaat ttcttcatta attttatcaa
      421 ctatgcctct actgcctatt aatttaatgc aataaataat aaatctttta caaaaagata
      481 ataaaaatat agaaaaatat tttttattgt ccttttggtt atggtaaacc acattctgcc
      541 tgcaatataa ctaaatatat gggtagatag taaaattaat tttattattt atatataatt
      601 ttataagtta cttttcaata atattgactg tcattaattt ataatattca ataaaatatt
      661 ttaatttagt taagaatcta tattgtaaag gagtattaaa ttaatgaact taaaattaat
      721 atggataaat attctaaacc cagtatttat taaaaatgaa ataaaaagaa aaaaaataca
      781 aattattatc tttttcttta taaactttgg tttaacttat tcattaggtt tactgttata
      841 ttataataaa tttattgatc cagaaaactt tgcatcattc atgatgatat tacctctatc
      901 ttcagttgcc attgcaaagt tttatactga aggattaaat aatgatatgt atgaatttta
      961 ttcactaatc atattatttt ttcttattta ttcattatta attgttctta agttattaaa
     1021 tctaataaat aataatgaat ttataattat aaacctaata ttaactttta taagtagctt
     1081 atcaattata atatattcat caaataaaaa aaatttatat cctgtaaaaa atattaaact
     1141 aggttcttta ttaattattt actttatgat ttctgtaatt gttccaacat catttatact
     1201 aatactacaa ggggctcaac ctaattatag tggtatcata aaatttatat ttactccaat
     1261 aacatcatta actactattt atattttttt tagtgaagaa tatgcctgga gaggtttttt
     1321 acagaatatt ttttttgata aatttggtaa aaagttagga gttataatat taggtatgtg
     1381 ttggagcttg tggcacttac cactaatatt tacattatat acacctgaag cgccaatatt
     1441 aggaataata ttacgttcaa tacatatagt tggaatttca atatttttag gatatcttta
     1501 tataaaaact aagaatatct ggttttgtgc tataattcat gttttaaata atagtgcttt
     1561 tcttatcaca aattctaaag aatcaactat cacttaccat gatatactaa tagtatctat
     1621 ggttgtttta attttttatg ttccatttct atttacaaaa gaatataaaa ataacttgga
     1681 gtaaatagaa tatccaagtt atttttatat ttttgcaaat ttccaacaat cctacagaat
     1741 actttaagct tagaagatat tattaaaatt tattataatc aactaattct tgatattggt
     1801 cacatttact ttatcactaa caaaatcata cttagaatct ctatagtaat accatacaaa
     1861 tataaagcta agtagattaa caaaagtagt caaaattcca ccttcaatac caaacattcc
     1921 tccatttaat agattaccat gagtgatttg tgtagttata atccctggaa cttgaagtcc
     1981 acttacaggc ataccatata taatcccctg aaatacattc catgcaaaat gataacctat
     2041 acacatccat atattcgacg attttataaa catatatgaa aaaagaatcc caataattat
     2101 aatattaatt acagacaaaa aagtaacatc aggattccat atatgaatca acccaaaaat
     2161 aacagatgga acaatcatta taaaataaat atttttacat cttcgtaaaa ctgccataaa
     2221 aaaaccacga tttaaaattt cttctgcaaa agcaactaaa ataaagacca gtatccaaga
     2281 aactgttaaa ggtgaaattt ttggtaccca tgaagtaaca tgaccaccac caattgttat
     2341 tgttataata aagattactg tacaattaaa tattcctaat aacattccta catatccttc
     2401 ttttttctta attctataag aatgtaatcc catttcacta ataggatttt tcataataaa
     2461 tctccataca attataggaa taataatcat aagtgaatct gttagaattt gaaatacaat
     2521 ctgtaaccca acatcattta accaattagc atattctgaa aaatagtttg tttttaaatt
     2581 aatgtcacct gtagcaacca ggatttttct tattatttcc acaagtatca tgcttaaata
     2641 atactgaagt atgtaaaagg tagccataac agctataata atccaccctg aacgtacttt
     2701 tttgtcttta ttcttaataa tcaagttgct ccatgatttg ttcatataga tgtcttcctc
     2761 ctaactatta tttttagttg tttctaaaat atattctatt aaattttttc atagtagtat
     2821 tttaccacaa aacttctgct tcaatgaagt aagcgtaata tattctctaa ctgtaattta
     2881 aactataaaa aatatataaa gtatatttaa agcaatattt atggacataa agcaatataa
     2941 acaatatata aaacatataa aactttactt aattatttct acataaaaac cacataaaaa
     3001 aggatgtaac tctagctttt agtgtaacat ccttttttta attaaaactt gtatttaatt
     3061 ttagaaagct gtctcatgac caacataaca agctatacca ttatccaaaa atatatcttg
     3121 taattcttca agatgacctt catcaacatc acccttatca gaatactcat attccttgcc
     3181 taattgaatc cattttgatt ctcctaatct gtgaaatggt aatagattaa tttctaccaa
     3241 attatttttg tgcataaaag atataatatc acttatattt tcaacactat cattaaaccc
     3301 agagataact ggtactctaa gtactaatct tccattccaa tcagaatttg caaggtttga
     3361 tatattttct aatattaaat cattatacac acctgtttgt tctttgtgtt tttctctatc
     3421 catatgcttt atatcaataa atgcaaaatc aatatcgtta aatattttat taaaaacttc
     3481 atttgataca catgcactcg tttcaatggc agtgtgtata tttacctcat gacactttaa
     3541 taatacttca tgtaaaaatt catgctgaag tagtggctca cctccactaa atgttactcc
     3601 tccattactt ctccaattgt tagaatcacg tttaattacc tgcacaagtt catctacagt
     3661 gtaaggtttt gcacataatt taaacgcatt ataataacat gagttgacgc attcaaaact
     3721 ttcacagtcc ttacagatgt tccaatctat aactggctta ttatcaagat taaagctcaa
     3781 tgcaccattt ttacacttac catgacatac agtacatcca ttttcatatt gacaagataa
     3841 ttcactaaac atcatatgtg gtcttacagt ccaactttct ggatttgcac accatttaca
     3901 actcagtgga catccattta aaaatacagt tgttctacaa cctggaccat catgaactga
     3961 aaagctttgt acatcaaaaa tcatgccttc taattgcttt tgactactca ttaaacacat
     4021 gtccttcaca agtaattgca ttcaatgttg aatataccca gtcttctttc tctaggccaa
     4081 cacatttgcc tataccttca tcattagctt caacaaaatt tttacaattt ttacattttg
     4141 gcattacttt tatctctgga catgctgcat catctaaatt aatcatttgt tttgataatc
     4201 tacaaattcc tttggttgca tctactgcac aaaaattcat acaatcacta tgctttctca
     4261 tattttacac cccttcatac tctgttctag caattacttc atcttgtatt ggtttaccta
     4321 attcacacca atattgagta aacccagcaa cacgtaccat taattgacga taattgtcag
     4381 gatttttttg tgcatctttt aatgtttctg aatctacaac attatattga atatggaacc
     4441 caccttttct taaataactt cttgttaaat ctaataattt tttagttcct tgttgtcctt
     4501 ttatagtagt tggatgaagt tttaaattca tctgagaatt ttgaactact gcttggtccc
     4561 aaatagttgc agattcaaat aatgcatata ctccattttt atctgttcct gcatatgcag
     4621 agactgaacc atctgaatat gttgttccac ttagtctacc atctggagta gccaaggtag
     4681 cagctccctg tggcccatgt gtagaaacag atatttggca agggtacatc ttcttagcat
     4741 ataaagattg tgcttcttca catacttttg ataaccatac ctcatagttt ttaagaatat
     4801 tatctgcata caaatcatta tttccatatt taggtgcatc aagacaggcc ttataaatag
     4861 catcatattt accagtctta tctactttta cttggtctgc catagaataa tttcctactt
     4921 ctaatgcatc tttaaatcca aaattattta atatggcatc cttcatttcc tctattgtaa
     4981 atgctttgtc atcatataca agtttcttaa gtgctgcaaa tgaattgacc atagtaacag
     5041 taccacaagt ttctacgttt aatgttgcat tataacgata tcccatattt cctatatgtt
     5101 gacctttgtc taaacagtct ggctttagta gtgaatttat tatagaagta tcaaattttc
     5161 tccatatatc taactcaatg ttatttgctc tttctaaaac atttattgct tgtttataat
     5221 aatctttaaa tacttctatg acttcttcat aagtatctaa tggcttatta tgaggctcaa
     5281 atacttgtat attcatacga tagtctttac cattcataag aacaagttct aaaatttttg
     5341 gattagctat aaagtgaact ccagagccag cagattgacc tgctccacct gcaatagagt
     5401 atgtttttcc gtttaaagtt aactgtttcc aacaccctgg agacgtttcc aaacatccac
     5461 ctaatgcaaa tgctcttgct tcttcaacag tcataccttc atcagcaaat tgtttcatca
     5521 taaatgttgt tccatttgag ttgtttaccc atgctggata accagaacca agctttgtac
     5581 attcagcagc tttcattaag aaatcttctg gaagcttttc atcatatagc atagttaaac
     5641 taggttgagg agttctacat ctcatacttg cttctaataa taactcttct agttcattag
     5701 ctcctgtaga accatcttct tttaatccac ctatagataa agtattaaat gtattgcctg
     5761 atagtactcc tccatttacg cccgctgaag caaaacagtc aatacaagtg atttttattc
     5821 tataaagctc taataattcg ataacctctt cttttgtaat tagtcctttt tctatatctt
     5881 gttcatacca aggatataaa atttgaccaa aacgtcctat agacatacca gatatagcat
     5941 cctcatttac tgatgctata tgaattgtat aagtcaactg aagagcttcc ctaaatgtac
     6001 gaggttgttt atgtgcaata tgttctaata tctccactaa atctgagtat tcttttttag
     6061 cttctaaatc tgtctctata ctttctaaat attttgcatg ttttgcataa tttaaaatcc
     6121 aagtttgtaa tccttcaata acttgaataa cagcctcata aaaatataga cggtccatac
     6181 caataagccc atctccagat gcatttcctg caactgcctt tttacattct tttgccattt
     6241 ctataattcc atctaatcca taatttaaag gataaaaata atttataact tctctacctt
     6301 gaggaagtgt ataccctgaa tcaaacatgc atataagtgt actcattagg ttttctttta
     6361 aatcataatc tggcatcatt ttttcatagt gaaaacctaa atcttcaaca gactttccaa
     6421 cccattcctt tgccattttt acaagtacag gtacttcttc ttttctcatt ccgaatttac
     6481 cagctattga aacgacattt ccaaaacttt cagtaacatt tcctccacca gacccaaatt
     6541 ttgtaagttc atcagctgtg ttactggcta atttctttgc ctcttctctc atttgttctc
     6601 cttgagcaac aaagaagctt tcacttaccc atggcattgg aaaagaacct ctataatggc
     6661 gtgtcttttg cattactatt ttctcaccag gtattatatt tggtgtcata tgtgaaaaag
     6721 cagctttaag agctttagct cttctaacta ctggtatatc accatctgat tttctatatt
     6781 ctctattata ccaatatgga aattccatat cagcagtaga taatgtatta taatatacat
     6841 ctaataagtc ttctgctctt ttacttgctt ttttttcatt aaattcactt aaattttctt
     6901 tattttgaaa atttgattta atattttttg cttccaaaat acttcttatt ttgtcttctt
     6961 tactttgact catttcttcc cctccttaat ctttctataa ttagtataaa actttttaag
     7021 aatgaaaaaa aagggtatat tacccacttt ttaaaataat ctttctatag aaaaaaataa
     7081 acttgaagca aatctaagcc aaagacaatc tgtatatcct aaaatttgtt gcaattcatt
     7141 ggaatataaa gattataaat agttttactt caagttttaa tatatactat atttattttt
     7201 attatattta atttcacttc tacttacttt tttgaaacaa tacttttata tttacaaatt
     7261 catctaactc tactgattta tctttaaatt tggaactgca tttaaactca tatcatgcgt
     7321 tttcccattt ataaaattat aatatcctgc acaccctatc atagctgcat tatctgtgca
     7381 taaaattaga ggaggatact taacagtaat accattgtct ttagcaagct ctgttatttt
     7441 agctctaagc cccgaattag aagcaacccc accagaaaga gttatgatat tgtatccttt
     7501 gtcttttact gcttttagtg ctttagtaga taaaacctct actacagcct cttggaaaga
     7561 tgctgctaca tcttcaacta ctatttcttc atttttcatt ctttttccat ttagataatt
     7621 taatacagaa gattttaatc cactaaaact aaaatcatag ctatcttctt ctaaataggc
     7681 tcttggaaat tctatagcat gtttatttcc attcttggcc agattatcaa taataggacc
     7741 tcctggatag cctaaattca tagctcttga aatcttatca aatgcttctc cagatgcatc
     7801 atctcttgtt tttcctaaaa tttcatactt gccataatct tttacttcaa ccaagtgagt
     7861 atgacctcca gatactatta atgttataaa aggaggtttt aaatccttat gctctatata
     7921 gtttgcactt agatgccctt ctatatgatt tactcctaca agtggaatat tcaaagtata
     7981 tgcaagtgct ttagcataag atagaccaac caataaagca cctactagcc caggtccata
     8041 tgtaactgcg atatggtcta tatcattaaa acctatattt gctttgtcta aagcttcttg
     8101 aacaactata tcaatatttt ccacatgttt tcttgaggcc acttctggaa ctacaccacc
     8161 aaatttttta tgtgtctcga tttgagtaga gattatgttt gaaagtactt ctctaccatt
     8221 ttttaaaact gatgcagctg tttcgtcaca actactctct atagctaatg ttattatatc
     8281 actcataaac tctacacctc ttttaattgg ttccacatta taattgcatc ttctttatta
     8341 tcactgtagt attcttttct tattccaccc attttaaatc catattttct atataaattt
     8401 tgtgctattt tatttgatgc tctaacttct aatgtcatag atgcaatatt attatcttta
     8461 cataaatcaa ctatgccttt tatcaacttg tcccctattt ttttccctct atagtcacta
     8521 tgaacagcca cattatttat atgcccttca tcaagtataa gccaaattcc cacatatccg
     8581 acaatttttc catttaactt agctactata taccttgcta cttcattaga caactctttt
     8641 ctaaaagact cttttgacca ataatcttca aaacaatttt tttctacttc aaaaacttca
     8701 tctatatctt ctgtagtcat ttcttctatt tttatatcat ctactattag ttttgtatta
     8761 tcttccatta tttagcctct tcattttttc atcatattgt acttcagctt gagattttct
     8821 gatatacata ggatttatcg tataacaagt atgtacatct atatttttat tatatttatt
     8881 taatgctaaa gagcataagc ttcctgcgtt agatacatta ttagctggtg aaggtatttt
     8941 tatatttttt atattctcta acttgtcttt atatttgtat acagcttctc caactattat
     9001 aaattcttca ttagttgata caatttcatc tactaaagca tcaaactcta caacatcaac
     9061 accatctaat tctatcatct ctccattttc aaacttgtat ttagctgaat aaacttgatt
     9121 tttctgtgca tctaatatac aacatatctt tctatcacag aaatttatgt tatttgctag
     9181 agattccaaa gaatttactg ctattattgg tatattattt acatgggcca tagcttttac
     9241 tgtagccata cctattctaa gtcctgtaaa cgaacctgga cctatacata cagctaataa
     9301 atccatatct tttatactta aatcactcat actcaacata ttttctatca ttggcataag
     9361 cttttgtgaa tgagtttttt tgttgtttac tgtaaactca catattaagt tatcatcttc
     9421 aacaactgct acacttgctg ccatagaaga cgtatccata cctagtattt tcattattta
     9481 atcaactcct caactatctc tttataaaac tctccttttg gagttaatat catttctctt
     9541 ccttcatctt tatatctcaa ttctatattc aaatattctt ttggaagtat atcttctatt
     9601 agattagccc attctattat acagattcca tttgaattta catattcatc ataaccaata
     9661 tcatacattt catcactact acctattcta taaacatcaa aatgatacaa aggtattttt
     9721 ccttcatatt catttattat agtaaaagta ggacttgtta tataatcttc tatccctaat
     9781 gaatctgcca aactttgtgt cattgtagtt ttaccagctc ctaaatctcc tactaaacag
     9841 ataacactgc cttcttttaa aagtttacct aatttatatc ctatttctct agttttattt
     9901 tcattttcta aatatatttt tgccatcaat tcatctccat tttgatataa tcgtcatgtg
     9961 aatttatatc actgcttaat taattatagt ataagcctag attattataa agtacttgtc
    10021 tttatctttt tttatctttc actattgatg gctgtatcta caccttatat acaatcatca
    10081 atagcaattt ttacatactc ttttgcttta tggttttgct tcaatgcttc tttacatatt
    10141 ctctcagatt gctcttttac atacttaaga gacttatagt tctcttttac tgcttcaata
    10201 cacatttttt ctgtttgatt ttttatatac ataagcattt ttccattttg tcttacaatc
    10261 tctatacata tatcttctgt atacttatct atgtaactta gtacatcttt aatattatat
    10321 tttttattta aatatcttat agcatttata catatttctt ctgtcttatt gttgacaaat
    10381 tgtatacttc ttccatcttg tttgacagct tctatacata ttttatcagt ttgtttattt
    10441 acatattgta atgccatacc attttgtctt acggattcta tacacatttt ttccgtttga
    10501 ttttttacat attttaatgc tttataattt tgcttaatgg cctctataca taattcttca
    10561 ctctgttctc taacgtatgc aagacacctg ccatcttttt taattgcttc taaacatatc
    10621 cttcttgttt gagtctctaa agcctttagt atacttacaa catctatatt ggaagaatga
    10681 cttattgctt ttataataag cccttctgtt ttatttcgta catacttaag tgcattacaa
    10741 tcttttttta tagcttcaag acacaagtat tctgtttgtt cttttacata ttcaagtgct
    10801 ttataattat actttattgc ttctaaacat aattcttcgg tttgattttt tacatactct
    10861 aatgccttgt aattctgcct tattgctaaa atacacatac catcagtttg attttctata
    10921 ttttttaatt cacgataatc gtattttacc ctttccatat tttcaatata ttcattagtg
    10981 atatacttta aagaatctcc taattttgta tcataaatac caatatgaat atctttccaa
    11041 ttactattaa aataataccc tttatcatct aaaaataatt tttttatttt tttagataaa
    11101 tgcatgaata tacaccccta tcattattaa attagttatt attaaaagtt tgattattaa
    11161 tctttatagt tttttaataa taactttatt ttttgtttat tataaattcg ctctgtatat
    11221 tgtagatacc tttttcatat tttaatagtt aatcgtttta attcttcctt tattttaaaa
    11281 tttaaatttg tctaaatatt tcttatttta tatacatttt ttgataaatt aataaagcca
    11341 taatatattt aatatatcaa tcacaatata ggactgaagt tataaataaa ttatggctat
    11401 tcaatacatt taattttata ttttcttgtc taattatttc tttattatat ttcccatttt
    11461 tttataaagt ggcaatgtta ctaaagatat tataacagcc ttcagcacat taaatggagc
    11521 tatcatccaa attacaaaag tgaataaatc atgaacttga ggatttatag ctgaacctaa
    11581 acctattata gcatctagtc ccataagttg accataaagt ggcaacatta caaaataatt
    11641 tactaatgaa ccaattatag tcatagatat tgttcctaat acaaaaccaa tcagtacacc
    11701 ttttaaatct ccacttctct tatatgaata acaaagtatc attacataag aaccaccaat
    11761 taatatattt gcaaattctc ctattcctcc agttgttgtt gctgttattg cttgtaacac
    11821 attttttact acaactattc caaatccaac taatggtcct agagacattc ctccgaatat
    11881 tgctggaata tctgataagt caatttttaa gaaatctgga aatatacctg gtattggtgc
    11941 ttgaataaac attaataaat aagatattgc agataaaatt gacattacta ctaaagttct
    12001 tgttgaaatc atattgcctc tttttgctgt gttttgcata attattttcc ccctaatcaa
    12061 tatgtttata ttttttagga aaaacaaaaa actcgaagac cctatcttcg agtttttatg
    12121 gatatagttt aaacaaacta aaataaactt atttatcttc cataaatatc ttctctcatc
    12181 cagactttac tgtcggcttt ggaatctcac caaatcaacc acctaagtag ttcgcgggct
    12241 ataccgccgg tagggaattt caccctgccc cgaagatctt ctttgatttt ttaattttcc
    12301 ttacactctt atattagtta attttttaat aattgtcaag ttattttttc tcatacacta
    12361 ctttgccatt tattatagtg taaagtacat tactttgaat ctctagtgga gaattatccc
    12421 aaattactag gtctgcatct ttaccaactt ctatagagcc tactctatct tctattccta
    12481 aagccttagc tggatttatc gtaattgatt ctattgcttt ttcttctttc ataccatgtt
    12541 ttactgcaat acctgcacat attggaagat attgaactgg tattactgga tggtctgtca
    12601 ttatacatac atcaagacct gcatttgaaa gtattcctgc tgtattaaat gtcaaatttc
    12661 taagctcaaa tttagacctt tctgacaaag atggccctac tattacagga aacccttctt
    12721 ccactaattc atctacaata agatgacctt ctgtacaatg gtctaatgta agctttaaat
    12781 taaattcttt tgcaattctt attgctgtaa acatatcatc tgctctatga gcatgtgcct
    12841 taaaaggaat ttctcttctt aaaactggta ttaaactttc catttttata tcatattcag
    12901 gtttttcaca gtcttcatca tcatgactct catacatatc aatatcctct aaatattctt
    12961 ctgctttttt taggttttct ctaagtaaag cagctatagc cattctagtt tgaggagatt
    13021 tatcatcctg accataacag ctctttggat tttctccaaa agcaatttta gatgcaactg
    13081 gattttttat taccatttta tcaattcttt ttccacatgt ctttatagct atacattgac
    13141 cacccataac atttgcactt ccaggggttg tacaaacaga agttattcca ccttcaaaag
    13201 cttctttaaa agttctatcc attggattaa ttccatctat aggatttaat tgtggtgtta
    13261 ttgggtcagt ctcttcattt ccatctgctc cttcaaaccc tataccatct tcccataaac
    13321 ctaagtgagt atgagcatct ataaatccag gaaacacaag tttattacta gcatctatta
    13381 cctctacatc taaaggagct atcaaatctt ctccaatttc tattattttt ccttcatcta
    13441 taagtatatc tccatgaatt atcccatttg ttatggtatt tattttacca ttttttataa
    13501 aaatcattca ttttcctcct gattttcaag actatcgttc ttattttaat atattttctt
    13561 actatatact tttacaaatt tttaacattt atacactcga gtaatcttat ttacaaatat
    13621 agaatctaag tactataacc atacataaac ttatctattt tttcattgat aaggcaactc
    13681 tttttttgtt taagtcaatt ccaatgactt ttacatctac tatatcacct actgtaacaa
    13741 tactcatagg gtctttcaca aaactattac tcatttctga tttatgaact aatccgtcat
    13801 tttttattcc aatatctaca aatgcaccaa agtctacaac atttcttatt gtacctttta
    13861 aagtcatacc ctcttgtata tcttcaattt ttaagacatc agttctaagt ataggtttta
    13921 taccttcttc tcttgggtct cttcctggtt ttttgatttc agctatgata tcttttaacg
    13981 taacttgtcc tacttccagt ttttcactta attccctcaa gccaatttct tttatttttt
    14041 catctatttc acctatattc ttattcttta catcatctaa agaatatcca attatctcaa
    14101 tcattttttt acatatatca taactttcag gatgcacacc tgtattatct agtggatttt
    14161 taccctctaa gattctcata aatccagcac attgagtaaa tgcttgaggt cctagtcttt
    14221 ttactttttt caattgtgct cttgacgtaa aatctccatt ttcttctcta tatgctatta
    14281 tattttttgc tatagcttta cttattcctg caacatgttc tagtagggag tatgatgcag
    14341 tatttaaatc tactccaaca ctatttacag aatcttcaac aactccatct agtacttctt
    14401 ctaatctctt tttgtttaaa tcatgctgat attgaccaac accaatactt ttagggtcta
    14461 tttttacaag ctctgctaat gggtcttgta atcttctagc tatagatata gctcctctta
    14521 ttgatacatt tatatctgga tgttcctcat ttgcaagttc agatgctgaa taaacagatg
    14581 ctcctgcttc actaactatc acatactgca cttcgctatc tatttctttt atcatttctg
    14641 atacaaaagt ttctgattct ctagatgcag taccatttcc aattgaaatt atatctatat
    14701 cgtatttttc aatcaatcct tttaaaactt tctttgctcc ctctacatca ttttgagggt
    14761 ctgttggata tactgttgta taatctagta gtttaccatt tttatctact acagctattt
    14821 tacatccagt tctaaatgca gggtcaaatc ccataactac tttgtcttta actggtggtt
    14881 gaagcaataa acttttaaca ttctttccaa atacacttat agctctttct tgagctattt
    14941 ctgttaaatg atttcttatt tctctttcta ttgatgggaa aattaatctt ttataagaat
    15001 cttctattga acttacgatt tcttctttat ttttgaaatt tttatcattt acatattcgt
    15061 ttattatgta atttaaaact ttatcattat ttatttccaa cttaaccttt aggaagcttt
    15121 ctttttctcc tctgtttatt gccaaaactc tatgtggagc catacttttt actgcttcgc
    15181 tataatcata atacatatca taaaccgatt tctcatcagt agcacttttg ctaactatca
    15241 taccttctct taaagctaat tctcttatat actttctaat cttagcatca tctgagacta
    15301 gttctgcaat tatatctcta gcacctttta gagcatcttc aatagaaaga acttctttct
    15361 cttcatcaag ataattcttt gcctctattt ctatattatc taaattattc tctagtattg
    15421 acaatgctaa attttctaat cctttttctt ttgctattgt tgctctagtt cttttctttt
    15481 gtttatatgg agcatatata tcttctactt cttgtaatgt ttttgctttt tctatatttt
    15541 gtgttatttc atctgttaat ttcccttgtt catctattag tctaactaca tcatcttttc
    15601 tactttgaag atttctcaaa tacattaatt tttcataaaa ttctcttagt gtaacatcac
    15661 tcatttcgcc agtcatttct tttctatatc tagctataaa tggtattgta tttccttcat
    15721 caataagttt taatgtatta tttatttgtt catctctaag attaaactct ttttttaaga
    15781 tttgatttat atccaattta ttcactccta atgttagttt ttcataagta taacaaaaca
    15841 gaacgaaggc tgagggttat cgtcctcagc ctaagtgctg taagtgcata ttaagcacta
    15901 accttcttat acatatatct taattacagt gcatatttat taaactattt tattcatttt
    15961 taagtattca ttaataaaca agtctatatt tccattcatt acactatcta catttccaaa
    16021 ctcagcattt gttctatggt ctttaaccaa tttatatggt tgaaaaacat atgacctaat
    16081 ttgactaccc caagttattt gtgagtattt gccttgtata tcttctattt tttccttttg
    16141 ctctaactct tttaattcta tcaatttcgc cattaaaagt ctcatagctc tgtccttatt
    16201 tagatgctga gacctttcat tttggcactg aactactaca ccagtaggga tatgtgttat
    16261 tctaactgct gaatcagtcg tatttacatg ttgccctcca gctccagaag ctctatatgt
    16321 gtctatcttt aaatctgatg gattaatttc tacttctata ttttcatcta actctggtgt
    16381 tacatctata gatgcaaatg aagtatgtct ttttcctgat gggtcaaatg gagatattct
    16441 cactaatcta tgaactcctt tttcactctt taaataccca taagcatttg ttccttctac
    16501 aagaattgta gctgtcttta tccctgcttc agggtctgat attatatcta aaagcttaac
    16561 tttataaccc ttactttctg accatcttat atacattctc aaaagcattt gagcccaatc
    16621 ttgagcatct aagccaccag taccagcatt tatagataat atagcattat ttttatcata
    16681 ctctccattt agaagagtct ttattttcat ttcagataat ttttcttcca ttgattctat
    16741 ggacttttct atatctcttt ctacagaatc atcatcttct tctaaaccta tttcaattaa
    16801 tacttctata tcttctaata agctttttaa gctttcatat tcttctaatg tctcttttaa
    16861 agatttattt tcttgaagta ctctttgagc gacttcatta tcattccaaa aatcttgttg
    16921 attcatcttt tcttcattaa tttgtatatt tttcatcaat gaagctatgt caaagagaaa
    16981 ccctcaattc ttctaaattt gaagccatct gctccatact atgtctatac tcttgtaact
    17041 ttaacattta atcctccgag attatcttcc acaacagttt ttatattttt taccacttcc
    17101 acaagggcat aagtcatttc ttccaacctt ttcatctttt ttaacagttt tacttgttgg
    17161 aagtgttcca tctgatggag aagatagatt ttcaacatct acaactgctt ttctttccac
    17221 tggagtttct attgttatat taaataaata tcttacagta tcttctttga tatgtttatt
    17281 catttcatca aacatatcaa aaccttccat tttataagca ataactgggt cttgctgacc
    17341 tacagcacga agaccaatac cttggcgtaa ttggtccata gcatctatat ggtctatcca
    17401 atggttatca acagcttgaa gtaagattac tctctcaact tctctcattc tctcatagcc
    17461 aacttgttct tcttttgaag tatatatctt catagctatt tcataaactt tttctgttat
    17521 ttcaactgga ttaagttttt ctatttctgg tatttctatg ctaccttttg gcaagaacag
    17581 attatacata tgttctttga atccttcttc atcaaatcct ttatcttgtg tataaagagt
    17641 aactgcttct tctattatag aatgagtcat tgattgtatt tgttcttgta aatcttcacc
    17701 ttctaataca cgttttctct ctgcatatat tatttctctt tgtttattca taacatcatc
    17761 atattgaagt acatgctttc ttattccaaa gtttttacct tcgactttct tttgtgctcc
    17821 ttcaatagac ttagataata ttctatgttc tatcggcatg tcttcttcaa gacctatttt
    17881 atctacaata ccagatattc tatcactacc aaacaatctc ataaggtcat catcaagacc
    17941 tatatagaat cttgaactcc ctgggtcacc ttgacgtcca gcacgacctc tcaactggtt
    18001 atctattctt cgagattcgt gtctttctgt acctattata gcaagtccac ctgcttctac
    18061 aacttgtttt tgttcttctt gtgtttgttg cttaaacttt tcaaatagtt tttcatactc
    18121 ttctctagct tcaaatagaa tttcattacc ttttacaggt ataccttcta ttggagtatc
    18181 tactctattt actatttctt ctttaaatcc atttcttctc atttctctct tagttaaaaa
    18241 gtctggattt ccacctagaa ctatatctgt accacgacca gccatattag tagctattgt
    18301 aacagctcca agtctaccag cttgtgctat tatttctgcc tctttatcat gatgcttagc
    18361 atttaatacc tcgtgcttta tgcccttttt ctttagtatt tgtgataata attctgattt
    18421 ttctattgat actgtaccta caagtattgg ttgattgact ttgtgccttt caattatttc
    18481 ttgtgctaca gcattaaatt tacctatttc acttttgtat acacagtctg gtaagtcttc
    18541 ccttatcata agcttattag taggtacttg gaaaacatcc attttgtaga ttgctttaaa
    18601 ctcttcttct tctgtttttg ctgtaccagt catcccagaa agttttttgt acattctaaa
    18661 gtaattttgg aatgttacag tagctagtgt tttagattct ctttgtattt taagaccttc
    18721 tttagcctct attgcttgat gtaaaccttc tgaatatctt ctaccaaaca taagtctacc
    18781 tgtgaactca tctactatta ctatttctcc atctttagca acataatcaa catctttctt
    18841 cattattaca tgtgctctta aagcttgatt tatatgatgg tataattctg tatgagatat
    18901 atctgttata ttatcaacat taaaatacac ttctgctttt tgtatacccg atgctgttag
    18961 agatacagcc ttatcttttt cttctaattc ataatcatct ggttttaagg ttaaaacaaa
    19021 tgtgtttgca tctgaatata agtgagttga tttgtctcca ggtccagata tgataagtgg
    19081 tgttctagcc tcatctatta gtatagagtc aacctcatcc actatagcat aatttaatcc
    19141 tctttgaact ctttgctctt tgtgtattac catattgtcc tttagatagt caaatccata
    19201 ttcattattt gtaccataag ttatatcaca atcatattgt tcttttctaa cttttggatt
    19261 ttgaccgtgt ataataacgc ctacactcat tcctaaaaac tcatagattt ttgccatttg
    19321 gtctctatca cgttttgcaa ggtaatcatt tactgttaca acatgtacac cttttccagt
    19381 aagcgcattc aaataaacag gagcagttgc aaccaaagtt ttaccttcac ctgttttcat
    19441 ttctgctatt cttccttgat gtagtactat acctccaatc atttgaactc tgtagtgtct
    19501 aagtcctaac actctcttag aaacttctct aactactgca aaagcttctg gaagtatatc
    19561 atctatactt tcaccatttg ctaatctttc tttaaatata tttgtcatat ttttaagttc
    19621 cgagtctgcc atagattcaa atttaggttc taatgaatct attatatcaa cagttttatt
    19681 gaactttttt aattcttttt tatctgccat gttgaataaa ttatccataa agctcatatt
    19741 ttacatctct cctcgttctt tattgtacta ttattcattt taccataaaa actatacttt
    19801 taatattaat ttaaaaagct atcgataatt tatttatcga tagctaatat gattaaatct
    19861 aaattgcttt attcatgttc tattatacca tatccaccat tattacgctt ataaactact
    19921 gctatttcat ctgaatctat gttcttgaac atataaaaat catgtcctat taattccatc
    19981 tgtaatacag cttcttcttc actcattggc ttaacactaa atttcttacg tctttgaatt
    20041 actaattctt gattttcatc cccataattc tcttgttcat cagctagatt tatctctgca
    20101 tcttggaatc ttatactctt gttgtcttta tgtttatctt gtaatctctt tttatatttt
    20161 tttaattgtt tacttaattt atcatataca acatctatag ctgtgtataa attttcctgc
    20221 atatcttctg ctctaattat aggaccattt acagtagcta ttgttacttc tattttttgt
    20281 cttgcttttc tcgcacttac tgtaactttt acatcagtgt ctggatgaat gtaattatct
    20341 aacttactta gtttagtttc gattttattt tttattgcat cagttaattc gatttgtttt
    20401 ccagatataa ttatgttcat aaatacatct cccttcaatt atgccagtat aagaaaattt
    20461 atactttaat aatatattct acacgaactc tcataatcct ctttttatta tttactttta
    20521 tgattttttc tattcaattg atagaattat ttatcatttt tagttacatt gatacttatg
    20581 tggattaata ttattacaaa cacctgtgga taatgtggat aaaactgtta ataactcttg
    20641 tttttgttta tttaaagcta tttttactcc tatttctatc cacaaaaatc tccattaatt
    20701 gtttattaat atgtgaattc atgtcataag atggtaattt taggaaatta tgtgtattat
    20761 atgccaatat acctttataa ttttttaata aatataaacc ctctaaaacc tccataatct
    20821 atcttttctt tcattattta tatttaaaac taattaaaag ttataaagca tactcaacaa
    20881 taatttcata tttaatacct attaacattc atatacccaa attataatta acttactctc
    20941 tttatttaaa ctaagtattt tatattcata tactatcttg aaattatatt tacgagttgt
    21001 ttaagctttt gtctatctat atcttcaaaa ggactgttat ttattctaat cgctgtacca
    21061 aaatgaaaat tacttgcctt agttaattcc tttatctttt ctatattatt aaaattaaga
    21121 cctccaccta aaagaatttt tatgtgatta gaactaagca tcatattctt tatcatttgt
    21181 atgttatcaa ctatacttcc tttccctcct gatgttaata tattcgtaat tttatcataa
    21241 tccttcaaaa ttttaacact atctattgta tttgattcat ctattgctct atgaaatgta
    21301 acatcaagat tatcacaaca tttcaataaa acatttagat ttttctcatc tatactattg
    21361 tttttatcca atacaccaaa tacaactcca ttagcaccaa tctctttaac cacacttata
    21421 tctttttgca ttatacttat atcttcttta ctgtatacaa aacttttcgc atgatgtctt
    21481 atcattacgt tcacaggtat ctttacactg ttaacaacac tttctataag accaaaactt
    21541 ggtgtcaatc caccttcagt taaagcacta actaactcta ttctatctgc accacaatct
    21601 tctataattt tagcgtcttc tactgacatt cctattattt ctaacataac tactcctttg
    21661 ctaattcata tattgcattt gcaaatatct ttgcatttaa tattatatct tctatatcca
    21721 tgtattcatc aggattatga gctattcctt tttgtcctgg aaatgaaggt ccaaacggaa
    21781 ctatatttgg cattactttt gcatacgtac ctccattagt tgttacggga gttccatcta
    21841 atgatgtaac cctttcataa gctagctgaa gctttttaac aagattactc tctttatcaa
    21901 aatatacagg attaaaatta gaaattacct ctatatcgat actatttgga aaactagctt
    21961 ttatttcatc caatacatct ttcaatttat aactaaaatc gtattttacc tttatatcta
    22021 atatagtatc actattttct atattcagct ctttatatgt aacaagcaca ttttcagaca
    22081 tattttctat aaaacctagg tatacatctt cttcataatt gattttactt tttattctaa
    22141 tctttgccat gcctttttca ccatatacaa caggatattt acaatctggt gtaaatccca
    22201 taataggtgc tttttctttt tctaaataat atggtatatc ttcaaatcca ctttcttcat
    22261 ttgtaccaaa tattattcta actctcttat ctaattttaa gtttaattct ttaatagcat
    22321 ataatccata taaggcagac attataggtc ctttattgtc tagtactcct cgtccataaa
    22381 ttcttccatt agtttcttct cccttataag gctgatgctt ccaaccatct ccttcatgta
    22441 caacatctac atgtccaatt acacaaacat aatcatcact atctccatgc tctgcataac
    22501 caatataatt atccaagttt ctaaccttaa atcccaattt ttctgatatt tctaatgctt
    22561 tattaagtgc ctcccctact ttttcgccaa aagggaagcc attttctgac tcccctttga
    22621 cactaggtat ttttacaata tctataatat cacttaataa atcttctttt aactcatcta
    22681 ttttattact tatgatattc ataaaaatct ccttattata aaactctatt ttaattatgt
    22741 aaccactact ttactcactt acttctattg gtgcttttat tctagcctca tatgcttcca
    22801 tccactcatt tgatataacc ttatgtatag tctttccatc tactctattt gaaatatata
    22861 cagtaggaga ttcttcttta gttactactg aaaaagtaaa atcagctata tttgtagcta
    22921 ctccccattc acctttatta ttcatggcaa ctaatgataa atcaccagct tttcctcttc
    22981 ttttgataag ctgtttatca agttcattta ctgcaatatc acatgcttct tgtggatgct
    23041 tcccttcttt cataagtcta actatctcat aagatataca tcccttcatt aaatcttctc
    23101 ccaaaccagt agctgtagct cctcctatac tactatcaac atagaatcct gaaccagata
    23161 gtgcagaatc tcctattcta cctcttttct tcataaacaa tccacttgtt gatgtagctg
    23221 cacacatttt tccagttttg tctaaagata tcataccaac agtatcatga ccagcatatg
    23281 ggcttaatcc tttgtctaaa gtctcttttt ttctcttttt ataatgtaac ttcgctctat
    23341 cagtcaacat attttttctt tcaaatccat ttttatgagc ataatcttca gcacctattc
    23401 caactaaaaa attatttacc ttctcataac ttaacttcct agctatgctg acaggattag
    23461 aataatctct tataccagca actgcgccaa tatctaatgt gttaccatcc ataaatgcag
    23521 cgtcaagttc tacctcacaa ttttcatttg gaagtccacc atatccaacc gatttataga
    23581 atggatagtc ttcaactctt cttacagcaa gctctacagc atcacctgct tccatgcctt
    23641 tttctaaatg ttctgatgcc tcagttattc cttctagggc cattctccat gtcgctatca
    23701 ttccccacat gttaaaattc ccctccttaa attatataga ttttactaat gtatgcttat
    23761 tataaatagt ataatattta aacttgctaa taattaatac tcttattgat aacaaaactc
    23821 ttctttcatc aaagttatat cttctttatt tgctattgct tttgccaatt tacatatgtt
    23881 atttaatgaa tcattaagac caattccacc tttttttgga gtcttaacta tacatatgtc
    23941 atttttatat tcgtttatca catctatatt ttcttctgac atagctgcaa aagctggtat
    24001 atctgtttta tcatttatat ttttagacag tattgctgac atcttagaaa agttttcgta
    24061 attaaagctt ggtccacaga ttactacatc agggtttaat ttttttacca tagctatcat
    24121 cttactcgtt acttcttctt gattatttac aaaaaattca tccccacaaa ataaggtagc
    24181 tattacctta gattcattta aaaattgctc catcattaca cctggtccta atgggcttga
    24241 ttttccagca ggaggtatat tacttttctc ttttcctcca gctccagctt gtatttggtc
    24301 caatatcata actattttct tcataatctt cctcctataa tactaaatca tcaaaagata
    24361 tatcatcatc ttcctcttca acagtttcat tttcttctct caagtattgc ttatctagca
    24421 tttttataaa tggtatatac ataaatattc ctagtataag aagtactaat tgtaagactg
    24481 caccttgcca tcctgttgtt aaaaaaccag agaatataat tggagttgtc cacggtaact
    24541 gaactccatt tgtaagaggc actaatcctg ctgacataca gaagtaagct attattatat
    24601 ttattgttgg aactattgca aatggtatca atagtattgg gttaagcatt attggtagac
    24661 caaatatcaa tggctcattt ataccaaata ttcctggtaa aattgatagt tttcccattg
    24721 actttatacg tttactttta catattaata acatagctat gactaatgat agtgtactac
    24781 ctgctccacc aaatgtcgca aacatatctt ggaattgacc tgttattatg tttggtattt
    24841 ttgaaccagc ttgaaaagca gctaagtttt cagctgatag aatttttaat attggattat
    24901 acacagcccc aacaacacta cttccattta ttccaaagaa ccagaataaa tgtaagaata
    24961 tataagcgat tgccatagca cctaaactat ttcctaattt taataatggc atttgtaaaa
    25021 acttaaatat aaattcatgt atacttccat atggtgtagc ttcaaaagct atcttaacta
    25081 aaaagaaaac taccataact attgcacttg gtattaatgc tgcaaatgat tttgatacag
    25141 ttggaggaac tccatctggc attttcaatg tccatccttt ttttacaact gcagcaaata
    25201 attttacaga ggttattgct gttatcatac ctacaaacat tcccttagaa cccatccaac
    25261 ctagtggtat acctgttacc atgtaaactg attctgttcc ttctggtgta tatggtatta
    25321 caaatggtgt tattataaaa aaggcaacta ttgcaactgc tgctgatgct attgggtcta
    25381 catctatttg ctttgcataa gaatatccaa tccctaaaac tgcaagtaga gtcattactt
    25441 caaatgttgc tacagttggt tgttgcaatt ttacagccca atctggacca aaaatttgac
    25501 ctacaaattc attccatcct tttataggaa aatttgctac taataaaaat aatgaaccta
    25561 ttattaataa tggtgatgat actaaaaaac catctctaat tgcaattaat aatttatttt
    25621 tacctatttt ttcagccaat ggcataagta ttctttccaa tctattcatc tatccaccct
    25681 catttcctat tattttttac tataattcta cgcttgttta gattttatta gctttatagc
    25741 aagttttaat actttttccc cattcatagt tccataatca acttcattga ttatatctat
    25801 aagttttcct tgagcttcaa actttggttt taactccttt agcatgtatt taacttgtgg
    25861 tcctaataat atacaatctg gatttttttc ttcaactatt ttgtcaattt ctgctatcgg
    25921 aaatgcctct acttctattg gtaaattgtg ttcatctgct accttctgca ttttatctgc
    25981 aagtaaactt gttgacatac caaagctaca aaataaatat acttttcttt tcatttttta
    26041 aatccccctt aattttttta ttttaatttt tgaatttctt ttcttaacat aatcatttct
    26101 tttataaggt ttctctcact catacaagtc attaaatggt cttgagagtg aatcaataaa
    26161 atagatatat ctgatttatc tcccccagct tccttttgta taagttcagt ttgtacttta
    26221 tgtgctttta aaatttcttc atttgcattt tcaattaatt catctgcttt tttaaaatcg
    26281 ttttcctttg catagtcaag tgcttcataa agcatagatt ttgcatttcc agcatgaatt
    26341 ataatcttta aaactatttc ttccattttt tcctcctaag ttgcttctct acttttagat
    26401 tatttatacc ttacaaacat ataatatctt ataaaaacaa aaaaacatgc acaacttttt
    26461 ccatcacatg gaaaattttg tgcttatcca tagttcacta tgaattttat ataagaatat
    26521 cttttacctt ttcaatgtca catttactta gaatatctag catattttca tcctctgtta
    26581 aattagatat ttctttaaat aattctctaa atacttttct atcatcatct tttttatacg
    26641 ctaacaaaag tataatcttt atatcctttc catttctaat ttttattggt gtttttaacc
    26701 ttgcaaaaca taaaacagat tgttttatat atttcatgtc tccatgaggg aataatattc
    26761 cttttccaac attggttgga tatgactttt ctcttgttat aatagattgt aaatactctt
    26821 tttctgcata atgtttttca attaataaat tagttaaata tgttatagct tcataaatat
    26881 catcatgttc taactctctt attaaataat cagacatcat taatctgttc ataagtttat
    26941 atgaagtgtc tttttctttt attttgtttg tgaactcttt aagtttattc tcatcctcat
    27001 cagtaaataa tggtgttgtt ataaaaattg gtttttggat attttcatac tcttgaaatg
    27061 caattataaa atctatagtc ttattaaagt tatctctttt taaatcttcc tctcttaatg
    27121 tttcaataat ttttatgtta tcaaatctct tttctatctt tacttttaat agcatactta
    27181 ctccaaaact aaatggacat acaatacttg cctttttatt tgattccctt ttgctgtatt
    27241 ttctttctag agaggtttga aagtgaagtg taagataacc aatttcatct tccgttattt
    27301 gttttccttt taattcaatt tctattgaac ttgatattac tgtaaataaa aaacaaaatt
    27361 tagtttttat gttatctaaa agtggatttt ctaagtaaac attgcttttc atttgatgca
    27421 ttgtaacatt caaatgacat attaattgtt cataaagtaa tatatcatta ttaaaattta
    27481 ttcctgattc ttctgatact aaatttataa ttttttttgt ataacttgct aattcttcat
    27541 ttagatataa agatttctta atattattac tatttatttg tttgttcata cccaatatta
    27601 aagattctat aaacaatttt tcttcataat ttaatactat ggataaatta gatttcaatt
    27661 catcttctat atccaatata agcattttta gcttaagctc tttcttagta tttgatactt
    27721 ttaaagaatt tcccagcctt attcgtatta tatttataag caaaaatagc atcaattgct
    27781 tgaatgatat atctgtaagt cttatatcca tatcctcttc tatagtaagc attatgtttt
    27841 ttacaattat tatatctact atatggaagt actctatttc atctatgttt aatctgtatt
    27901 tatctatata tttaaataag aatgatacta acattattct tatgtctttc tcatcccctt
    27961 caatatatat accactgcct tttttagtcg agatatttaa attataatta tttaatgcta
    28021 ctgataattt acttatttct tctctgacaa tatttttatt tatgtacaac ttattagata
    28081 aatcatttaa agtaactttt ttattattac aaagtagtaa atttagtatc tcaacttgct
    28141 tatgaagctc actatttact cttttaactt cacctcgcaa cttctgattt accagtattt
    28201 tgtctgttcc atctccacta aatttaatcc caatattagg ttttcttttg atataagcat
    28261 tacaaaaagt agataaccat tcatcaatat atttgcaatc atttcttatt gtcctttctg
    28321 aacactcaaa atcattggca atcttattaa catttataaa ctcttctttt aatagcaatg
    28381 ttgttaataa attttcttgt cttttattca aacatatcac ctctttatga ctcaacctaa
    28441 atttattata tataaaaaag agctatacat aaaggtatgc tagctctctt ttaatatgat
    28501 atttagctga cctggttttt gaccccacac tcgcctactg gagggttcgc ttgggttcgc
    28561 cgcactacta ctctctctcg attttattat cggtaggtct tacttctaag ccgcaccatg
    28621 atcattaacc caatttttag tgttaactta cgtggatccc tttgcctgcg actggcttgg
    28681 actttcaacc acagacctaa atatcactta ttcattttaa tattttaaac taaaattgtc
    28741 aatatataag attattccat aatataatta tcatttgctt ttgtaagtag agtcaataca
    28801 aaaaccttat tagcacctga taactttaaa agtttagaaa tttcgtttgt tgttagacca
    28861 gtagtaaata tatcatctat taaaagtata tttttattat ttattaattt aacattttct
    28921 ttaacaacaa atacattttt taattcttct tttcgttctt tcttattcaa tttatatagc
    28981 attcttgtat atttttttct acttatgcaa tctaataatg gaatatttac tattttactt
    29041 aaattaaatg ctattttttg tgcctgatta aaacctcttt tatttagcct ttttttatga
    29101 agtggaacaa ataatatata atcaaatttt atgttttcta aatataattt ttctttcatt
    29161 atttgagcta tatacttagc cataaaggtt ttttggttat acttcagccc taacaccatc
    29221 ttttttgtca catcattgta ttcaatacaa gatattgatt tatcaaaata aaagtcttta
    29281 ttaaaacaat aactacactc ttcaataaat tctttttcaa ttgaatgacg tattattggt
    29341 tttccacact tcatgcaacc atcttgtata aaattcattt ctttaaaaca acttttacat
    29401 attgaataag tatttgtttt ctttatggat ttatcacaaa ttatgcaact tatattctca
    29461 ggatatataa aatccaaaca tttattaatc atatttttaa aattcttaat aaaattatca
    29521 ttgcatattt tcatatttat tctatcaaca acccttcttg tttaaattta tttagcttat
    29581 atcctaaatt tgaatacctt tgattaactc tattattttt tatcatatat tcaagatatt
    29641 tcacatctcc aactaataca actaattttt ttgctcttgt tactgctgta tataataaat
    29701 tacggctaag taacatagga ggagcccacg ctattggcaa tactacaact ggaaattcac
    29761 ttccctggct tttatgtatt gttgtacaaa aactatgatc aatttcatct aattcatcat
    29821 ataggtatga tacaatttta gtctggtcaa ataatatata aatagttttc ttatctttat
    29881 ctatgtgata aacatatcct atatctccat tatagatacc ttctccactt tctttttggt
    29941 cttctgtttc ccattttttt gtataattat tttttacttg cattacctta tcgccaactc
    30001 taaataatct tttagaaaaa ttttcttcaa ctttaaattt ttcttttttg ttaagatact
    30061 tctgtaactc tatatttaga ttagtaactc ccaattcacc ttttctcatt gaagataaaa
    30121 cttgtatatc ttttaattta tcaactttat aaaatttagg taatctttca ttaaccaatc
    30181 ctattatttc atttaaaatt tcttcattag ttgattttct tataaaaaag aaatctttac
    30241 cttttgtatt tagataaagt ggttctccat tgtttatctt atgggcattt acaattatca
    30301 tactttcttg cgcttgtcta aatatttcat ttaatttaac tacatttatg atattagaat
    30361 taatcatatc cttaagtaca tttccagcac ctacagaagg taattggtca ctatctccaa
    30421 ctaaaattac tcttgttcct aactttatag ctctaagtaa attgtacatt aagataatgt
    30481 ctaccattga tacctcatca acaattatta catctgaatt tattgggtct tcttcatcct
    30541 taaaaaaagt taaatcatca tctgttgaaa atcccatttc tagcaaccta tgtatagttt
    30601 ttgcttcttt attagaagtt tcactcattc tctttgctgc tcttcccgtt ggagctgcca
    30661 gagtcacact tttaccatta ttttcaaata tatctatgat agcattaatg gtagttgttt
    30721 taccagttcc tggtccacca gttataatta atactccact attaacagat tctttgactg
    30781 ctaaaatttg tttttctgct aacttaattt tcttatcttc ttctaaaaca ttaatctcgt
    30841 tatctatatc tatttttaag tcttcaaatt catactgtga taattttact atttgactac
    30901 atactccatt ttcagctaaa tagtatggca taaggtatat aagattttca ttgtttactt
    30961 tctctatatg tattttttga ttataaacta gcatcattac acactctttt attatttctc
    31021 catttagctc caataatttt tccgaatctt gtattagaac atgctctggt aaatatgtat
    31081 gcccattact taaagattta tttaaagtgt ataagattcc ctgacaaatt ctatctttag
    31141 agtttttatc tataccaatt ttacttgcta tactatcagc tactttaaat ccaattcctc
    31201 ttatatcttc agcaagttgg tatgggtttt tatttataac ttctattgca ctgcttttat
    31261 attttttata tatttttagg cagtaatttg gtgttattcc aaaaggagat agctgtatta
    31321 ttatatttct caattctctg tcttcttcat aactttttac tatttgtttt acttttttac
    31381 tccctatacc ttctacttct tgtagttttt ctggtgaatt ttgtatcacc tctaacgtat
    31441 ctacaccaaa cttatcaatt attctttttg ccattttttc accaatacca tgtatcattc
    31501 cagaagataa gtaaacataa attccttcta aggatgatgg tgttactggc ataaaactat
    31561 tcacttcaaa ttgagtccca taaatcttat gatttaccca ctttccttca acttctatgc
    31621 tttctccaat tgctaaagta ggcatacatc ctacaaccac aatttcatca ttttcattta
    31681 ccaggtgagc tattgtataa ccattatctt cgtttttaaa gactatttca cttatcattc
    31741 cttctaattt ttccattttt atctcctaaa aatactaata atcgctccat ttaaatgtta
    31801 gtataatttt atatattaaa actatgataa tcgtagaaaa gttttatatt tttatactta
    31861 acgtaatttc caactattat acattttatc agaaacaaaa aaaatctgca tccataaaat
    31921 atggtaccat gaaatacagg taccatattt aaatagctat tttattttaa ttactctata
    31981 tttagagtat aaattaaatt tcataagtat attacagtac taacttattt cagatttatt
    32041 ctccttgtac ccctcagttt tagtaattct tctataaagc atacatagta aaattaaaat
    32101 tcccatgtaa cctgtatatg gatatagtgt acctactaac ttatcaaatg gcagtaaacc
    32161 tcctatacaa gctaatatac ttaccactat tgttataatt ttaaacttag ggtggtcatc
    32221 ttctacaaat cggtttgtta ctgaccataa caatggtaca gctgtagtgt atattcctag
    32281 taaaagtact actgagaata aaatacctat tattggagat atcttatcag ctaagtaaag
    32341 tgctggtatc tcttttgtgt atatatttcc tatgtctgaa agtaatgcca aattcatcat
    32401 tatagctgct gccataagtg ctactccacc tactatacca ccccatacag catctttctt
    32461 atttactgca gaagctccca ttcctgtcaa gaatgttatt actattatta cattgtaaca
    32521 agtataaagt actcccgaga aatatccatt tgatgtagca gttttaatat ttaaactatc
    32581 aaccatattt ccagcatttg ataaagcatc aatattgcta aataaactaa ttgctcctac
    32641 taaaagtgta aatattatta ttataggtcc tatattacct agtattttag aaagccttgt
    32701 caaacctaat gaaacagtta ttagggaaac gattgccata ccaatcctac ctacatatgg
    32761 atttaatcca tagtactctg ataatgtagc tcctgctcct gcaatcatta ttactaatgt
    32821 tccaaataaa aacaatggac caaaccattc aaaaaatgtt ccaagatatt ttccacaata
    32881 tacttgataa atttttattg gctccttaag tttcaattct cttcccttat ctataacttc
    32941 tgctccaaac catgaaaata gtaccataga gattattcca cctataatac ccgcatatcc
    33001 ataaaacgta aaaaattgca gtatttcttg accagttgca aatccagaac ctattacagt
    33061 agcaacataa gctccagcaa aacttataac cgttttaata tttactttgc ctgacataca
    33121 ctactccccc caattaaaat tatttttaaa gtgtaagttt attaagatta tattagactc
    33181 attattgtga tatttcaata tatttttaat tatttaacat tagttaacac attcttaacc
    33241 atcctttaac atatatccca taatatgtat aaatttagta gagtattata taaaatgtat
    33301 tgaccagatt aaatactgtt tattcattat atgatgataa attaacattt attaaaaata
    33361 tttaactcat aataaaaaag ctgttagaaa gtaatcgtaa aattacattc taacagcttt
    33421 ttagttaaaa attattcacc taaagcatct tttcttaact gctcaacctt gtcagttctt
    33481 tcccaaggta aatctatatc agttctacca aagtgaccat aagcagcaac ctttttataa
    33541 agaggctttc ttaaatctaa gtctcttatt atcgctcccg gtcttaaatc aaagtgttta
    33601 tttactaatt caacaagttt ttcttctgaa accttgcctg tcccaaaagt atctataaat
    33661 atagataatg gtctagctat acctatagca tatgcaagtt ctatctcaca tttgtctgca
    33721 agaccagccg caacaatatt ttttgcaaca tatctagctg cgtaagcagc agatctatca
    33781 acttttgtag ggtcttttcc tgagaaagct cctccaccat gtctagaata tccaccataa
    33841 gtatctatta ttatttttct tcctgtaaga cctgtatctc cttgtggtcc tcctataacg
    33901 aatcttcctg ttggatttat ataaatttta gtctcttcat caagtaattc tgctggtata
    33961 acttccttaa taacatgatt aattaaatct tctcttattt tatcatttga tactgtttca
    34021 caatgttgag ctgatataag aactgtatgt actcttacag ctttacttcc ttcatattca
    34081 acagtaactt gagtttttcc atctggtctt aaataatcaa ctaaacctgt ttttctaact
    34141 tctgtaagtc ttcttgataa tttatgtgcc aaagatatcg gaagtggcat taattctgga
    34201 gtctcattac atgcaaatcc aaacattata ccttggtctc cagctccaac tttttctatt
    34261 tcttcttcta tctcttctcc agtcttactt tctagaccct catcaactcc catagctata
    34321 tctccagatt gttcatcaat agaagttata actgcgcaag tatcacaatc aaatccatat
    34381 tttgctcttg tatatccaat ttctcttact gtttctctta ctaatttagg aatgtctaca
    34441 taagcagatg tacttatttc tcctgctact aaaactaaac cagtagtaac tgtagtttca
    34501 caagctactc tagattgtgg gtctttttct aataatgcat ctaatattga atctgatatt
    34561 tggtcacata tcttatcagg atgtccttct gtaactgatt ctgacgtaaa taaatgtctt
    34621 gccattttta ttccccctta tttattctta atttttatta taggttttac cttgttttta
    34681 attttagaaa tttactcaaa ataaaaaaac ctctccttta taagaagagg ttaataatcg
    34741 taattacata ctaattaact gacctcatct ttcaagactt ttgtcttgta ggaattagca
    34801 ccttttccca tttgggtggt tgctgggctt cacagggcct atccctcagc ctctcttgat
    34861 aaggtaatca agatttaagt tttgttttac tttactagct tactattttt ttaaaatttt
    34921 gtcaatattt ttagtcatat tttttctatt cctttttttg taagacaaat aaaattttct
    34981 atctatctga aatttaaagt taggtctttt taatgctttt tattcatata tttttttgaa
    35041 gggggtgttc ctattgtatt tagctaaagt aaactacagc gatgatgatg ttatacagat
    35101 gctaagttca gttctaaaaa ctataattaa tgaaaatacg attgttgttt gcataggaac
    35161 agacagggct ataggtgata ctttaggccc tttagttgga acaatactta agaacagtaa
    35221 ctttaaatac cccgtttacg gtacactaga taaccctatt cacgccttaa atatatatga
    35281 gtctttagat actataaaaa atacacatat acaaggtaac ttcttggcta tagatgcttg
    35341 cttggggtcg cagagtaaca taggtaatat acagattaga gaaggaccta tcctgcccgg
    35401 aaaaggtgtt ggtaaaaaac tacctcaaat aggaaattat tctatagtag gaattgtaga
    35461 taaaattgat gaaaataata aactttcatt taataatata cgccttagct ttatattaga
    35521 tttagctgaa acaatagcct tggctttatt agtatccacc taatctaaat ataaactaaa
    35581 tgataaaatt ctttatataa aaaggtagat attttagagt atctgattaa atactccaaa
    35641 ttatctacct ttttactttt atatttcaag tttttatttt tctactaaag caaacattaa
    35701 ttcaccttta cagacaagtt cttcacctac atatgcctta gcatctgcct tagctatatt
    35761 ttttctaaga gttgtcattt caacttccat agttaatgta tctcctggtc ttacttctct
    35821 cttgattcta actttatcta tacctgcaaa tacacctagt tttcctttgt tttcctctac
    35881 agacatcatt gccactccac atacttgtgc tagagcttct actattagta ctcctggcat
    35941 caaaggatat tctggaaagt gaccttggaa aaatggttca ttaactgtta tattctttat
    36001 accaacagct cttttcccaa cttctagctc tgtaatcttg tctactaata aaaatggata
    36061 tctatgtggt attaattttt ttatttcatc tatatttaac attctaaact ctcctaatta
    36121 ttttcttttg aaagacccac cagtttcaag taagtctatt gaacctaaag ctattcctgt
    36181 accttttgca acacaagata atggttcatc tgctattgta acagttattc ctgtcctctg
    36241 ttctattatt ttatctaatc catataataa tgaacctcct ccagtcatta ttataccgac
    36301 atctcctata tctgctgcta actcaggagg cgttttttcc aaaacagcat gagtagcaac
    36361 tactatttgc tcaacacatt ctctaagtgc ttccaacatt tctgttgaat ttatagttat
    36421 agaactagga agtcctgtaa ttaaatttct tcctgttatc ttcatatatt tttcttcttc
    36481 tctcttaaat gcagaaccta tttcaaactt gattttctct gctgttcttt ctcctataag
    36541 aagattgtgt tgttttttca tatatttaac tatagcatca tcaaatctat ctccaccaac
    36601 ctttatagat tcacttacaa cagctcctcc tagagatatt acagctatat ctacagtacc
    36661 tccaccaata tctataatca tattaccatt aggctgtgat atgtctacac cagctcctat
    36721 ggcagctgct attggttctt ctatgatata tacttctcta gctccagctt gtctcgtagc
    36781 atcttctact gctctttttt ccacttctgt gacacctgtt ggtacgcata ccataattct
    36841 tggcataaaa aatcttccaa atcccttttt atcaactatc ttatctataa aagattttaa
    36901 catcttctca gttacatcat aatctgaaat tacaccatct cttaaaggtc ttatagcgac
    36961 tatattacct ggtgttctcc ctatcatctt tttagcttct tctcccacag ctaaaacaga
    37021 atctgttctt ttgtctatcg ccacaacaga tggttcttct aaaacgattc ccttaccact
    37081 aacataaaca agcacatttg cagtacctaa atctatgcct atatcagctc cagccatttt
    37141 ttcaactcct ttatttataa tattagatta tattataagc ctattttaat actcctataa
    37201 taaagcatat acaaaaatct cgctttaatc aagagaaaat aaatcttttg agagtattat
    37261 tattttgcta tttataatta cttaatatat ttctttttat aatttaattc aataaaaaaa
    37321 gtaggttttt aacctacatt tttttatgtt ccttctcata ttttaatttc gttgctaatc
    37381 cccctctaat atgtctctct gatttatttt tgtccagcac atttttaact tctttggcaa
    37441 gggatggatt tatttccttc aatctttctg taacatcctt atgaattgta cttttactta
    37501 ctccaaatgt cttggcggtt tgtcttactg tagtgttttt ttcaagtata tattttgcta
    37561 ccactatggc cctttcctct atatgagatc tcaaagatta cccccctcac ataatagctt
    37621 taatgatata tatgtaaaaa caccaaaaaa tataacaagc ttaaccaaat atgattaaac
    37681 ttgttatact attacttaat tagactcatt gggtctatag atttttctcc actatacgcc
    37741 tctaaatgca catgtatacc ttcttcactt tctatttgag aagtactacc tacagtacct
    37801 agagattgtc cttctgttac cttctgttct ttcttaacac taacattttt atctagattt
    37861 gaatatacta ctacaatgtt attgtcactt tttattttga ctgattgtcc atattcttca
    37921 tcatcaaata catctactac tattccgttt aatagagatt ttacttcttt gcctttagta
    37981 caactaatat ctacaccttt atgagtttcc caaacatcaa gtgttttaga ataactaggc
    38041 tctttttctg aatatcctct tattacttta tctccaatgt aatttaattt tgttgtactc
    38101 gatttatttt cctcttttga cttagctttt tctaagtttt gttttgaatc cgttgcagta
    38161 gggatagcat ctttcttgtc tttttcaatt aaatgtattt cctcttcact atctttatta
    38221 gcattttcca taattccttt attagaagcc aatttatcta cattattatt tgtaaaccaa
    38281 actccaccta ctgctaataa acaaacacat acaaacaaag ataaataaaa accatctttt
    38341 tctaacagct ttttcttcat tttgcacctc caaatatatt tctacatttg gattattgac
    38401 gtgtttttgg cattttatac aattattagt atatatcttt tatttttgta tctgtgtagt
    38461 aatgtgataa tatatcataa tatttataac cctcttctgc cattccttct gctccccact
    38521 ggctcatacc aacaccatga ccatatcctt ttaccacgaa atctatgtat ccttctccaa
    38581 attttatgtc aaagtttgca gagttcaact taaaaacagt tctaatgtct tttccagtca
    38641 attctttatt tcctaatttt attttttcta cagttccggc atcacttctt ttagttattg
    38701 aaacttgttt acttaaatta ttcacatcta tcacaatagt gctatatgcc cttctaagac
    38761 ttttaacaaa atctgtgtta cttattttaa gtgttgacgc aaatttaggg gaatacttat
    38821 cataaggact ttccacagac tttaaataag gatattttgc agaaaatact tcttcactat
    38881 tttctgtttt tcctgaagat gtagaaaaat aaagaggaag tatcgcctta tcattataag
    38941 ttattatttg acctttagtt cctctaactg cttcttggat tttggaatat ttattcttaa
    39001 tccattcttc accatttaat tttttaagag tatcataact cttatattct tgacaatgtt
    39061 tataatcagt acatactact gcatttttat gtttactaga tttaccatgt tcctgtttat
    39121 atactacata tgttctagct gctacagatt gagcttttaa agcttctata tcaaactctg
    39181 aagacatctc accagctagt actccacata aatagttctc catgtccatc ttttcggttt
    39241 tccctgttat atgattatat acattgataa ttggtgcttt tttatttaca gtttcatagt
    39301 tcactgtatt tttttcttct ttattacctt tgtcttcaat atcacttttt ttaatagttt
    39361 tgtttataga tactgggctc tctggttttt cagttaattc tacattttta taagaaacta
    39421 aagttataag tgatggaact aacacagagc aagtcacaaa tcctaacaaa acaaccaatg
    39481 ggttcttcat atactctcct ccttagcttt taaaaccttg tatttaagta tatgaacaac
    39541 cctattaatt tataactttc ttctataaac caattattaa tcttctacta tttcgatttg
    39601 accacctagt gctgttatct tcttatctat atcaacataa cctctttgga tatggtatat
    39661 ttctcctatt tgagtttctc cttctgctat aagaccgcat aaaataaggg ctgcccctgc
    39721 tcttaaatca gtagcgttta ctgctgcacc gtgtagctca tctacaccat taacaaccgc
    39781 acttcttcca tctattttta tattagcacc cattctatta aattcagcaa catgcataaa
    39841 tctgttttca aaaacagttt ctataactac accagttcca ttggctacag taagcatagc
    39901 cataaattgt gcttgaacat ctgtaggaaa tcctggatgt ggtaaagttt ttatatctat
    39961 tggttttaat acttttggac ctacaactct tacagaattg tccatttctg ttatttcaca
    40021 accagcttct cttaatttag ctacaactgg ttttaaatgc tccattaaaa cattttcaac
    40081 agttatatca ccttttgtca tagctgctgc aaccatataa gttgctgctt ctattctgtc
    40141 tggaattaca ttatgttctg ctccttttaa ctctttaaca ccttttattt ttatagtatt
    40201 agtacctgca cctttaacat ctgctcccat ttcgttcaag aagtttgcta aatctactat
    40261 ttctggctct tctgctgcat tctctattat tgtagtccct tctgctaaag aagctgccat
    40321 cattatgttt tcagttgctc caacagatgg gaaatctaaa tataatttat ttcctactaa
    40381 cttttctgtt gctgcttcaa caaaaccatg gtccatttct atctttgcac ctaaagcttt
    40441 aaatcctttt aaatgtaaat ctataggtct tgttcctata gcacatcctc ctggcataga
    40501 aattttcgta ctattaaatc tagcaagcaa tggtcccata accaaaaaag aagctctcat
    40561 ctttcttaca agctcatatg gagcttcaca agtttttata ttgcttgcat caacagtaag
    40621 tgtattttct ttatattcaa cttctgctcc tacatgtctt aataaatctg atataacatg
    40681 aacatctctt aaatttggta ctccatttaa tgttgatttt ccgtttgcta ataaagtcgc
    40741 tgctattatt ggtaaaactg cattttttgc accatctatt ttaacactac ctttaagtgg
    40801 attactcttt tttactatta tcttagccat attttttgat ctcctcataa ttaataatct
    40861 aattttataa ttggtgtggc aatatatatg agtgtttttc cgtcatcctc attatattta
    40921 attcctatat ttaaattaat tttttcccct aaatattcta attcataatc atttaatact
    40981 ttactatatg ctgttataga taaaaagttt acgtctttaa cttcatctat ttgcttagca
    41041 ctcatattat ataatatttt ttgtaaaata tcatcatatt tgttgttttg taaccttttt
    41101 gtgtattctc caacaataca agcagacaca tctacttgag atgaatattt atttaacaca
    41161 ttttctacgt tactataaat aacctcttta tgtttatata ctttgttatc caatatgtca
    41221 actactatgt aactttcttt gttattttta tttattcctt ttatagaaat ttctttatcg
    41281 ctacctttta tagtagcaca taattgtatt ttatcgccag accctttttg attccaattt
    41341 attccttttt tatccaactt tagattgtta attatttcta taaaaatatt atgaaattct
    41401 ttatttgata aattatgatt tataacagaa ttaattttaa cattataaaa tttaaaattt
    41461 gcttctgata tttcaagagc tttacttaat ctattgtatc tagtatttat acttgtatct
    41521 gcataagata ttgtcattcc tataatcatt aatataaaaa agcttatagc taattttact
    41581 tttttcatag taaaaaatcc cccttaaata tgtttttctg tataatagaa ttattaacaa
    41641 atttaagaga gatatacttt ctcaatatgt atttttatac atttttgtat ttttcatcta
    41701 ataatctctt tcaaactctt caatctcaat tttctctatc cttctcctgg acttgccaat
    41761 ttcttatatg tatcaaatac atcttgcatt aattcttata tattctcttc tgtaatataa
    41821 attacttagt ctatacttaa atctataatc tataatctat aatctataat ctataatcta
    41881 taatctataa tctattcata ttttaccaac aaaataaaca gataatactt ttttatcaat
    41941 ttccatagct ccaaatgaac atacctaagt acacttccca atacacaatt tacacactct
    42001 tcctaataaa tcaaaaacac ctttgtttta aacaactcta ttgcactttc aaaaacttta
    42061 tttgtgttct cccacttcaa ttaaatttga attatcaaga ctccagccca tccatccatc
    42121 actataaagg gaggtatttt ccactcctat gacatttgca tatgttaata cttcagcagc
    42181 acgccatcca cttccacaca taaatataag ctgtttattc acatctatat tttccttgtc
    42241 ccacatttct aaaatctcat atttatttct cattgtatta tcaatattac gatattcttc
    42301 tagtgaaaca ctatcactac ctgaatgtcc atataaagct cctggtatac gccctttttt
    42361 atcataatat gtatatccag atacttttcc tatatgttca tcccaagtac ggttatctac
    42421 tagtataaac ttattttttt cttttagttt ttgtcttaat tcagatgtag taacaattaa
    42481 ttgtgagtta actggtatat ctgctccaaa attagtacat gaatgttttg gattactaat
    42541 aaattctaat tcatatcctg ctgataacca tgagtttgtt ccaccattca aaactcttac
    42601 atcttttact cctatatatc tcaatataac agctagtcta taagatgcca taggtgtact
    42661 acttgaaact attacagtat catcctttgt taatccatag tctaaagcaa acttagttaa
    42721 gttatcatca ttatcaagca tccatgttgg aggaggttct ataatatcag tatttacatg
    42781 aacacttgta ggtatatgcc cttttgtata cgattcttct ctccaactcg cttcaatcat
    42841 ttttatattc tttgaatctt caaatgtctc aggaattttt ccatctaata tatcttttat
    42901 tataaaagca ggaactatca tttgataatt tttatatctt tccattggaa gattttcgtc
    42961 gtctgcccat tgtttaatat catatttata tagatattta tatccttttt tagataaata
    43021 atctgctaca accaaagcat cttttccatt tgcatcatac aatactatat ttttatctaa
    43081 atcaattctt ttagttttca atgcttgttc taacacttca tcttttctat ctgagtatac
    43141 acttaaccaa ttagcagaaa aatctactgc tccttttata tgtccacctc tttttactcc
    43201 atctaacttc cagccattat aagcatcatt taagcgagta tcaactataa cccaagcgtt
    43261 atcttgcact ttttcttgta aaacttcagt agatattgcc ttaagattaa caaaataatc
    43321 ttctttcttt tcttttttaa aatcatttgt cataatttat actcccaatt taaaaaaatt
    43381 tttatttgaa attattttac taaaataaag taattttctt atactctatt agcttcatta
    43441 tattctttta taaatagttc cttatattct tattttaaac tactcacttt atcttatcac
    43501 aaggttacta ataccttgta ttttaatttt tctcataagc tattattttt ttatctgata
    43561 ttgactatat gtttattaag tactcactat attttatatg aactatattt atcgttccct
    43621 atacctggta tggtctatat atttatcatt ttacagatga tttaatatca atctttttat
    43681 aaaatttatt atagcaaaaa caaaacaaat ttaatattta tctaaaaaac tcatcctata
    43741 aaatacaaat aacaggatga gttcttttca ataaatatta tctatttaat ttttaatctg
    43801 tttttattca actgttactg atttagctag atttcttggc ttatctacat cgcatcctct
    43861 tagtacagag acatgataag caagtaattg cattggtaca actgctaata ttggtgataa
    43921 aatatcatct gaatttggta tatagattat tttatcagca gctttctcaa catccttatt
    43981 atggctttga gctattgcta ctacataagc tcctcttgct cttacttctt ccatattaga
    44041 aaccattttt tcaaataact tttcttgagt agctatggca attacaggag ttcctttttc
    44101 tattaaagct attgttccat gctttagctc tcctgctgca aaagcttctg catgtatata
    44161 tgaaatctct tttaatttca atgaaccttc cattgctaag ctatagtcta tacctcttcc
    44221 taaatagaat gcatgttcag aactaacaac tgttttagca acttctttta tatattcttc
    44281 attgtctagt atttcttgta tttttgatgg tatttctttc atcttagaaa tcatactatc
    44341 ataaaattct ctagttattg ttcctttttt gatagcaaag tctaaagcta tcatgtataa
    44401 agaagttatt tgagtagtat atgccttagt tgatgcaact gctacttcag gtcctgccca
    44461 agtatagaat acatcatctg attctcttgc tatagatgaa cctacaacat tagttattga
    44521 aagtattctt gctcctttag cctttgaatc tcttaatact gctagagtat ctgctgtctc
    44581 accagattga ctaactaata ttactaatga attttcatct acaaatgggt cgctatatct
    44641 aaattctgat gctatatcag ttattactgg tatatttaca aatttttcta tggcatactt
    44701 accaagtaat ccagcattat atgctgttcc acaagccact atataaactt tatttatttt
    44761 ttctaagtct tctttagaaa tatttatact gtctagaatt atatttccat tatcatcaag
    44821 tcttctttct aaagtttctc ttactcctgt tggttgctca tgaatttctt ttgacataaa
    44881 gtagtcatat ccacctttag acgcagcttc tacatcccaa gttacatgaa atacttcttt
    44941 ttcaacaaga tttctattag agtcataaac tgttacattt tcgtctttta gatgaactac
    45001 ttctccattt tctaagaaat aaacatctct agtatatttt aataatgcag gtatatctga
    45061 tgctataaag ttttcacctt caccaacacc aactacaaga ggactatctt ttcttactgc
    45121 aactaattca tttccatgtt ctttacatat aacacctaat gcataagctc ctcttaattt
    45181 tgatatagtt ttgtatacag catctaataa attaccctca tagtatttat ctactaaatg
    45241 tgctattacc tctgtatctg tttgagattc aaacttaaca ccttcagaaa ttaattcttc
    45301 ttttatttcc atatagtttt ctattatccc attatgaaca actgctattg ttttggcttg
    45361 attaaaatga ggatgtgagt ttacatcaga tggttctcca tgagttgccc atctcgtatg
    45421 ccctatacct aaatttccat caataggatt cttttctaag tcttctgcaa gtacagaaag
    45481 tctaccttta aactttctaa tattaagttc tttttcatta gaactattaa ctgctactcc
    45541 tgctgagtca taacctctgt actctagctt agaaagccct tctactataa cttctgctgc
    45601 ctttctactt cctaaatatc caactattcc acacattatt tgtgtcctcc taaaaatatt
    45661 atttatatat tttaagagtt aggtcatata agtttacttt ggcttccctt tgtccatagg
    45721 attgctccta ttatttaaag aagtctttcg atggtaaaca caccgcagag catccgccga
    45781 caattcgatt aactctgacc tcgtcaactt agttcctata ttactcaata attatgtcta
    45841 taactaagtt ctggcgctta gaaaggtgtc ctcagtattt atatctgaga atacccttta
    45901 aattacgata atttttcttg tataagatta gctaagtttg ttgctaattc ttttatttga
    45961 ccttcctctt taccctctaa cataactcta actaatggct cagttcctga tggtcttatc
    46021 aaaactctac catttccgtc taaaatagat tctattcttt ctatctcagt ttttatttct
    46081 ggatattcca tatatttgtt cttattttca ttttttattg ttgcatttac taatacttgt
    46141 gggtattggc tcattattga tgcaatttct gataaaggtt tcttttcttg caagattata
    46201 tttgcaagta ttagagaact aagcactcca tctccagtag tgttgtaatc taaaaatatc
    46261 atatgtccag attgctctcc accaagatta tatccatttt taaccatatc ttctaaaaca
    46321 tatctgtctc caactgctgt agtagataaa tttattccat tttccttagc agctattgtc
    46381 aaccctatat tactcataac tgtaactacc aaagtatctt gtgccaattt attatttttc
    46441 tttaaattta aggcactcaa tatcattata tggtctccat caacaatttg acccttttca
    46501 tttactgcaa ttaatctatc agcatctcca tcatatgcaa gacctaagtc agcattatgt
    46561 tccaaaacag ccctttgaag ttgttctgga tgtgtagagc cacatttata gtttatatta
    46621 tttccatctg gtgaactatt tattgaaatt acacttgctc ctagttcatc aaacactatt
    46681 ggtgccactt tatatgacgc accattagca cagtccaaaa ctacttttaa tcccttaaag
    46741 tcagtgctta ttattgattt taggtagtct acatagtctc tttgtgcaca atgttcatgt
    46801 aattttcttc ctacattttc accaattgga agacaatcaa ttttgtctat atcgtctata
    46861 tattcttcta ttttcaattc aatttcatca tctaatttat atccattctt attaaagaat
    46921 ttgattccat tatattcaac aggattgtga gatgcagata taaccacacc acaatcagca
    46981 ccatattttc tagttaaata tgccactgca ggtgttggta ttattccaac agtaataaca
    47041 tcacatccaa cagacataag tcctgctatt aaagatgctt ccaacatatc acctgatatt
    47101 ctagtatcct tacctactac tacttttact ctgtggtctc cttgagctaa gacaaatcca
    47161 ccagctctac caagtttata tgctaaatca catgttagtt ctgtatttgc tactcctcta
    47221 actccatctg ttccaaaata ctttctcact aaagattctc ctttcataat tgaaaagctt
    47281 gtaatttgta ttatattttt atagttcata aaatatcatt ataggcttaa tttcagtcat
    47341 aaaaatattt taatacttat cagcaaaaaa gacaatagaa ataattctat tgtctttttt
    47401 ttgacatctt tttctttatt agttagttgc tttagaacat gtagcatcca tacctttttg
    47461 taaagcttct ctgtttaatg gaacgaattt ttcttttcta ggtccgaaaa cttttttgaa
    47521 tgcttctagt acagattcta tatctacagt atcagatact tttaagtaag cgcctaacat
    47581 tatcatgtta gcaactttat catttcctaa ttcagctgct aattcatttg ctggtatata
    47641 ataaacatct acatctgttc tatcaacttt ttcttttatt aaagaactat ttactattat
    47701 ttttccacca ggaataacat catctttgaa tttttcaaat gctggtatat ttaataatat
    47761 agctgcagtt gcatcatctg ttataagtgg agaaccaact ggctcattag atacagttac
    47821 tgcacagttt gctgtacctc cacgcatttc tggtccataa gatggtaacc aagaaacttc
    47881 ttttccttct agcattcctg cataagtaag taattgtccc atagacataa caccttggcc
    47941 tccgaagcct gcacatatta ctctagctgt agacatttac ttcacctcct caacttcaac
    48001 atttttgaaa tttcctaatg gatagtatgg tatcatgttg tctcttaacc attgtaaagc
    48061 atcgtttgga gctagtcccc agtttgtagg acaagtagat aatacttcta ctattccaaa
    48121 tcctaatcct gcttgttgaa cttggaatgc tttctttata gcttttttag cttgtctaac
    48181 atgagctgga gtatcaactg ctactctttc tacaaataca gctcctgtta atgtagctaa
    48241 catttcactt actcttattg gataaccttg agtttcagca tttcttcctg attgagcagt
    48301 agtagctctt tgtccaacta atgtagttgg agccatttgt ccaccagtca taccataagt
    48361 tgtattgttt acaaatatag tagttatttt ttctcctcta gcagctgcat gaactatttc
    48421 agcagtacca attgaagcta agtctccatc accttgataa gtgaatactg tattttcagg
    48481 atgaactctt tttattcctg tagcagcagc tggcgctcta ccatgagcag cttcttgagt
    48541 gtcacagtta aaatatttat atcctaaaac tgaacatcca actggaacaa cacctacagc
    48601 atcacctaat actcctagtt cttctaatac ttcaccaact aatctatgga ttataccatg
    48661 tgtacatcct ggacagtagt gagtttgagt atcttgtaat ccttcagttt tcttaaatac
    48721 aacagccatt atctagcacc tcctgcaacc aattctccgg caataatttt tttagctttt
    48781 tcaactattt ctgctggtgt tggagtcatt cctcctggtc ttccatggaa gtaaactggt
    48841 aatttacctt ctactgccat tttaacatct tccaccattt gtcccatact catttcaaca
    48901 gtcaatatgt ttctagcatt aggaatttgg ttgaatgctt cgaatgggaa tggccataat
    48961 actttaggtc ttataagacc tgcttttatt ccttcttctc ttaatatatc aattgcgctt
    49021 tttactactc ttgaagtagt tccataagct gcaaatacaa attcagcatc ttctgttttg
    49081 tacatttcgt attgtacttc attcttttcc attgcatcaa atttttcttg taaatgccaa
    49141 caatggtctt ctagtacttc tggctctaag tatagagagt ttattacatt aggttttctt
    49201 tttcctttag ttccaacagt tgcccaatct ttaggaggca attctctttt cttctcagga
    49261 gctctaaatt caactggctc catcatttga cctatcatac catctgcaac taccataact
    49321 ggtgatctgt aataatctgc aacgtcaaaa gcttccatta tcatatcaac agcttcttga
    49381 actgtagctg gtgcgaatac tggagttctg tagtctccat ttcctccacc tcttgtagac
    49441 ataaagtagt cagcttgtga aggttgtata cttccaagtc ctggaccacc tctcattaca
    49501 ttaagtacaa cacaaggaac ttctgctcct actgcatatg ttataccttc ttgctttaaa
    49561 gcaactcctg gtgaagatga agaagtcata actcttgctc ctgcacctgc tccaccataa
    49621 accatgttta tcgcagaaac ttctgattca gcttgaacga acgctccacc tattttaggt
    49681 aactctcttg ataaatattc tggtaattca ctttgtggag ttattgggta accgaagaaa
    49741 tatttgcaac cagcttctat agctgctttt ccaaatgctt cgttaccttt cataagtatc
    49801 ttagccatta aaattccccc ttaaatatta attaaattaa tctctttcta ctgttataac
    49861 tacatctgga cacatagttg cacaacttgc acatcctatg catttttcca tttcaaaaac
    49921 agttgctggg ttataccctt ttttgtttat tacatttgag tctaattgta tgatttttac
    49981 tggacatgct tcaacacaca atccacaacc tttacaacgt tcttgattaa aagatacttt
    50041 tcctttagcc atttacctaa gcctccttaa actttctata tatttgagct caaactacat
    50101 ccagtcttct ctcatatata attttatagg aaaaatttct ccttctaaat cttttggtaa
    50161 ctgttcaaca agattttcta aacatgcaac atatcttatc ggtatattac atttttcaga
    50221 aacttctttt gcaactttct gacctcttaa aacatcatca atagtagtaa acctaataag
    50281 atgagtatta ttaattagac ctgttacctt taatttagaa gatttttcta tttcttttat
    50341 atattggata acttcttcag aagtttgagt tttctcccta tttgcattta ttacaaaaag
    50401 catatcataa tcgccttctt ttaacaaatg actaaatctt cctataaccc tagcacctac
    50461 attatctcca cctaaatcta taacagaatt gtatgaatgg tctaccatag gagacattac
    50521 ctctgctgat actgctggta aatctaatgt tggagcatta attgagctat ctattggttg
    50581 tatacctaag gatttcatta actctttctt ttctctagtt ctaaagtata catttaccac
    50641 atctaaatcg gctatagcaa ctttgccaga aaccatatct cttaacttaa caacatagtt
    50701 catcgcaaat tcacttttac cacttccata gtgaccagtt atgattctta ttcttttatc
    50761 attagttatc ataaacttga gcctcttctt caccagttaa aactctaagt ccaccttgag
    50821 ctaatgcaat catttcatct tcacctggat aaacttttac atctgctata aatttaactc
    50881 tatctgcaat catttctgta aacatttttg aatatgcgat tccaccagtt aataatattg
    50941 cttttacatc tcccttaaga actgcagcac tagctcctat ttctttagag atttgatatg
    51001 ccatagcttc atatgctaat ttagcttttt catcaccagc ttcaattctt tcttcaactt
    51061 ctctagcatc attagtgttt aagtatgcaa ctaatccgcc attacctttt attttctttt
    51121 taatttcatc ttgagtatat tttccactaa agcacatttt tactaatgca cctactggta
    51181 gtccaccact tctttctgga gagaaaggtc cttctccatc taatgcgttt gcaacatcta
    51241 ctattttacc atttttatga gctccaacag aaactcctcc acccatatgt gcaactataa
    51301 gatttatatc ttcatatttc ttgtttattt ctctagcata tcttcttgct attgcctttt
    51361 gatttaaagc atgtactaca cttgctctac ttatttcagg cataccagaa attctagcaa
    51421 catcttctaa ttcatctaca acaacagggt ctactatgta tgaaggaaca tttacttctt
    51481 cacctatttg ttttgctatt attccaccta ggtttgaagc gtgttctcct aaaactccca
    51541 cttttaaatc ttcaatcata gcagcactta ctgaataagt accacctttt ataggtttaa
    51601 gaagtcctcc tctacctact acagcatcta attcagatgt ttttactcca ccttctttta
    51661 gagcttcttc tattacttgt ttacgaaatt caaattggtc agacaccttc tcatattttc
    51721 ctatttcttc tgaagaatgt cttaaagttt tttcaaatac taaatcctca ttatcaaata
    51781 cagctatttt agttgatgtc gaaccaggat ttattgttaa gattttaaat attttgctca
    51841 tttgcctatt tcccccttaa aattatgcct ttgctgccat taaaacacct aaagctattg
    51901 agtttagttt agtttcttca ctgtctgctc tagaagttaa tattattggt gctttagccc
    51961 caactataac tcctgcattt tttgattttg agaagaatac caaagcttta tataatatgt
    52021 taccaccttc aatatctggg gctaataata tatcagctct tcctgctaca ggatgattta
    52081 tacctttatg tttagctgct tctaaagata ctgcattatc aattgcaaaa ggtccaccaa
    52141 ccatacaacc tttgatttct cctctttcat acatttcttc tagttcttta gcttcaactg
    52201 tatctttcat ttttggattt actttttctt ttgcgcatat tgcagcaact tttggttcac
    52261 ttatatctaa tgaatgtgct actgtgcaag cattttctat gatttgcttt ttagtatttg
    52321 tatcaggagc taagttcata gctgcgtcag ttacgaaaaa taatctatca tatccctcta
    52381 catcaaatac tgctacgtga cttaatacat ttccagttct aagacctact tctttattta
    52441 aaactgcttt tagtattatt gatgtgtcta ctaagccttt cattaccatg tcggcttttc
    52501 cttgtgaaac taattcaaca gattttagag atgcttctgc taaatctttt atatctatca
    52561 gttcataatt ttcgatatcc atgtctatgc tttttgcaat ttctttagtc ttttctatat
    52621 ctcctactaa aatggcattt gctatttttt cttttctagc catttcaact gccattaaaa
    52681 cttctttatc ttggcaacat gctactgata tagttttagg tcctctttct tttgcaaact
    52741 taattacttc ttcaaaactt ctcatgcatt tccacctcat cttgaatttt ttgaaataga
    52801 actttttata tctcaattaa attataactc gttcagcaac gttttcctag agataattga
    52861 aatatttaat tcaaaatatt tatttaaatc tatttatcag tcttttttca tatatctagc
    52921 gctttttaga tttaacaaat atctcattgt ccttatttta taatataact aaaataaaca
    52981 agatgcaaca aaaacataaa attaacaaac ttaattttat aggttttttt gtcgcatctt
    53041 gtaacaacta aatattcgaa atatttgttc attccacttc aacaatatta ggttctatat
    53101 ttattttttt aaattgatat gttgtttcat attttatttt atatttacta tcttcctcag
    53161 gaccttgtga taaatcaata tataatgaaa tatctttttt atttaactta ctcaaatcct
    53221 ccattgactc tacaacaact tttatatcta catcagaaat tacatttgga ttatccatat
    53281 ttgttgggat atttcttaat tcaatatctc ccgcattata taaaaattct gcactcaatt
    53341 gttttgtatc atttaattta attgttatag agctatcctc aagagttata ccctctggaa
    53401 tttctaagct aacttctttt tcttcaccat tagccaaatc agctaagtca ataggttttg
    53461 tcttaatata acttattttg tctatatctt ctttctttcc ttttattgta acttgttcct
    53521 tacttaattt atagtttttc agtacatcat tatctttatt atcatttaga cttactctta
    53581 ttgggacaat tttttccttc aatagttcta tctttgcagt cacaaaggat gaacttaatg
    53641 ttactccttc aaccttagtt ccatcactat ttaatggtat taattgcaat tttttagaaa
    53701 aatcatctgt ctcattacca acatctagat tagctcttac acttttgact tctttaacta
    53761 gagttcttgg acctgataca tcgacaaatt ccttactaag ttcaatttta tttatatttc
    53821 tttttgaatt tccacttact tctaccttta tatctctttt ttcttttatg tttttttcaa
    53881 gatttactac taaaacatca tgcttaaatt ctagagtaac accttgagga atatttgctt
    53941 ttaaatatac ttccttctgt ccttgtattg ggtcttcaat ggttccatat acatgtatat
    54001 cttctttttt aacactttgt acctttgata aactaccttt tatatataca tctgctgtta
    54061 atttttcgtc tggatatata acaagatttt tatcctttaa atcactcata ttacttatag
    54121 atacaggtat atcttcaaac cctttagttt cttcagggtc aactacagcc ataacataca
    54181 tccataatgc aattgcactt aaaaatgata ttatttttat tttggtatta ttttttagtc
    54241 tatttatcat ttaaatatac cacctttgaa aaaacttctt gtttctgtat ttgtttttaa
    54301 attactacgt aatatattca tcattctttc tctagaaata tctctatata acttacctgc
    54361 tttagcaatt gatacgccac ctgtttcctc tgatacaatc aaagttatac agtcagacac
    54421 ctcacttacc cctattcctg ctctatgtct agtacccaaa tctttactta aatccttact
    54481 ttctgtcaat ggcaaaaaac atgcagctgc ttttacctta gaatctctaa ttacaacagc
    54541 tccatcgtgt aatggtgtat ttggtataaa tatatttatt aatagttgcc tagaaatttc
    54601 agcatcaata atagttcctg tatttattat atcacttatt ctagtttctc tctccattat
    54661 gataagagct cctatttttt gtctagaaag tgaatataaa gcttctacaa tttcttctat
    54721 atttctattg agagtttctt cagaagtatt tacattcttt ccaaataaat taaactttgc
    54781 tcttcctata tgttcaagtc ctgctctaaa ttctggttga aaaattataa gagcagctat
    54841 aactccataa tctaaagctt taagagatat ccaataaacg gtatgcaatt taaaggtgtt
    54901 actaagttga gttgctaata aaagaaatat tataccttta aacacttgtt ctgctcttgt
    54961 atcttttata aacataaata ttttgtaaaa aatatacgct actatagata tgtcaattaa
    55021 atcatatata ctcattctta atattatatt aaaaaatcca tttaaaaaag aatttatatc
    55081 taacacagtt ttatcctcct gtttgataac ttcttaatta tttacactaa gtattatact
    55141 atataaatct aactctatac aaactattta acttttatgt aaataattct agttttatat
    55201 ttggagattg ttaaataatc tctaaacaca ttaaaaatat caacttaata aatacatatt
    55261 tcttattaaa gttagttttt actcaaataa ctcaaaccat caaggcgcga atacaaaata
    55321 gtactcgcgc cttaattcag ttttatgttc taaaatatct taatatatct ttgtttaata
    55381 tatattaatt attataaatt ctataatcca cttattaact ataaacaaat acaaaatcta
    55441 aatattactt atcatcaata ttattccatt agattcattt ttatattaaa gtaataactt
    55501 atttcatatc tagattagat aaatttattt taatatctta ctataaacta tcattaaaac
    55561 ttattatgta taactagata taatctccta cagtgaaaat aatacacaat acctaaagtt
    55621 atatatccat ttcacagtat aataatttat ttagtataac ttataaatat tacattaaat
    55681 tgtaaattca ctatagtctc taatttttta taatttctta tacttattgt ttagacaaaa
    55741 atatgctcat gaatctcttt ataaataatt tcataagtta tttcaatata taaataccat
    55801 aaagtataca atataatgta tataactctt actaattagt tatatttatt atatttaact
    55861 gatgccttca taaacatctt gtagactatt atacattacc ctccgtatgt ttacaatatt
    55921 aatgaatata ctgtaactct attagaatat actgtaattt ttacatagtt taaagtttat
    55981 aaataaaaag acacaggtaa tatacatgtt tcctgtgtct ttttaaacaa tataaaagtt
    56041 tactataatt tatagtaaac ttttcttaat gagcgcacag ggattcgaac cccggacaca
    56101 cgccttagaa gggcgttgct ctatccagct gagctatgca cccaagttat tatggagcgg
    56161 gaaacgagat tcgaactcgc gacttcaacc ttggcaaggt tgcgctctac cactgaacta
    56221 ttcccgctta tttaatttgg cgacctggaa ggggctcgaa ccctcgacct ccagcgtgac
    56281 aggctggcat tctaaccaac tgaactacca ggccgcgaat ggtgggacca acagggctcg
    56341 aacctgtgac cccctgcttg taaggcaggt gctctcccag ctgagctatg gtcccatttt
    56401 tggagcgggt gaaggggatc gaaccctcac agctggcttg gaaggccaga actctaccat
    56461 tgagctacac ccgcatattt aattgaattg gtgactcgta ggggaattga acccctgtta
    56521 ccgccgtgaa agggcggtgt cttaacctct tgaccaacga gccgttttaa tggttgcgga
    56581 ggcaggactt gaacctacga ccttcgggtt atgagcccga cgagctgcca actgctccac
    56641 cccgcgatat tgttttataa gtgccgaaga ccggaatcga accggtacga gaggtaagtc
    56701 ccgcaggatt ttaagtcctg tgcgtctgcc agttccgcca cttcggcttt tttggctcca
    56761 agggtggggc tcgaacccac agcctaccgg ttaacagccg gttgctccac cgttgagcta
    56821 ccttggaaca tttaacgtgg ctacgtccta ctctcccagg cagtttccca ccaagtacca
    56881 tcagcgctag agagcttaac ttctgtgttc ggaatgggaa caggtgtatc ctctctgcta
    56941 ttgtaaccac ataatcttta tgcttaatat ttctattaag tttttaataa gtttatagaa
    57001 tctagtaata ctagtttctt tagagttagc actctaaaaa ctacacatat atctta
//
LOCUS       DAYAKB010000019        56887 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.019, whole genome shotgun sequence.
ACCESSION   DAYAKB010000019 DAYAKB010000000
VERSION     DAYAKB010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56887
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.019"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..204
                     /locus_tag="ACGI3L_001373"
     CDS             <1..204
                     /locus_tag="ACGI3L_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197088.1"
                     /translation="KSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYVSS
                     MYAIKEAKLESRVNSGRVKQYNG"
     gene            712..1095
                     /locus_tag="ACGI3L_001374"
     CDS             712..1095
                     /locus_tag="ACGI3L_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFG9197089.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            1097..1447
                     /locus_tag="ACGI3L_001375"
     CDS             1097..1447
                     /locus_tag="ACGI3L_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197090.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(1548..2006)
                     /locus_tag="ACGI3L_001376"
     CDS             complement(1548..2006)
                     /locus_tag="ACGI3L_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197091.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLEEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(2051..2839)
                     /locus_tag="ACGI3L_001377"
     CDS             complement(2051..2839)
                     /locus_tag="ACGI3L_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9197092.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQEGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2978..3415)
                     /locus_tag="ACGI3L_001378"
     CDS             complement(2978..3415)
                     /locus_tag="ACGI3L_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HFG9197093.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            complement(3649..3783)
                     /locus_tag="ACGI3L_001379"
     CDS             complement(3649..3783)
                     /locus_tag="ACGI3L_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197094.1"
                     /translation="MGILEGAAMIREIAIKIAKEKGITEQKAWPEAVKEFKEKYELVL
                     "
     gene            4237..4746
                     /locus_tag="ACGI3L_001380"
     CDS             4237..4746
                     /locus_tag="ACGI3L_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197095.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4773..4919
                     /locus_tag="ACGI3L_001381"
                     /pseudo
     CDS             4773..4919
                     /locus_tag="ACGI3L_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            5152..5688
                     /locus_tag="ACGI3L_001382"
     CDS             5152..5688
                     /locus_tag="ACGI3L_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFG9197096.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKK"
     gene            complement(6115..6915)
                     /locus_tag="ACGI3L_001383"
     CDS             complement(6115..6915)
                     /locus_tag="ACGI3L_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197097.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(7110..8708)
                     /locus_tag="ACGI3L_001384"
     CDS             complement(7110..8708)
                     /locus_tag="ACGI3L_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9197098.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            9036..9212
                     /locus_tag="ACGI3L_001385"
     CDS             9036..9212
                     /locus_tag="ACGI3L_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197099.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            9386..10516
                     /locus_tag="ACGI3L_001386"
     CDS             9386..10516
                     /locus_tag="ACGI3L_001386"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_process: GO:0051144 - propanediol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-propanol dehydrogenase PduQ"
                     /protein_id="HFG9197100.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            10757..11107
                     /gene="eutS"
                     /locus_tag="ACGI3L_001387"
     CDS             10757..11107
                     /gene="eutS"
                     /locus_tag="ACGI3L_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HFG9197101.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            11115..11564
                     /locus_tag="ACGI3L_001388"
     CDS             11115..11564
                     /locus_tag="ACGI3L_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HFG9197102.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            11666..12241
                     /locus_tag="ACGI3L_001389"
     CDS             11666..12241
                     /locus_tag="ACGI3L_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9197103.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            12234..13643
                     /locus_tag="ACGI3L_001390"
     CDS             12234..13643
                     /locus_tag="ACGI3L_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HFG9197104.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            13827..15260
                     /gene="eutA"
                     /locus_tag="ACGI3L_001391"
     CDS             13827..15260
                     /gene="eutA"
                     /locus_tag="ACGI3L_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HFG9197105.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            15278..16642
                     /locus_tag="ACGI3L_001392"
     CDS             15278..16642
                     /locus_tag="ACGI3L_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HFG9197106.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            16655..17536
                     /gene="eutC"
                     /locus_tag="ACGI3L_001393"
     CDS             16655..17536
                     /gene="eutC"
                     /locus_tag="ACGI3L_001393"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008851 - ethanolamine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HFG9197107.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            17556..18209
                     /gene="eutL"
                     /locus_tag="ACGI3L_001394"
     CDS             17556..18209
                     /gene="eutL"
                     /locus_tag="ACGI3L_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HFG9197108.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            18220..18921
                     /locus_tag="ACGI3L_001395"
     CDS             18220..18921
                     /locus_tag="ACGI3L_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HFG9197109.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            18924..20393
                     /locus_tag="ACGI3L_001396"
     CDS             18924..20393
                     /locus_tag="ACGI3L_001396"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HFG9197110.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            20489..20776
                     /gene="eutM"
                     /locus_tag="ACGI3L_001397"
     CDS             20489..20776
                     /gene="eutM"
                     /locus_tag="ACGI3L_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HFG9197111.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            20903..21664
                     /locus_tag="ACGI3L_001398"
     CDS             20903..21664
                     /locus_tag="ACGI3L_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HFG9197112.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYRYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            21677..22306
                     /gene="eutD"
                     /locus_tag="ACGI3L_001399"
     CDS             21677..22306
                     /gene="eutD"
                     /locus_tag="ACGI3L_001399"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization phosphate
                     acetyltransferase EutD"
                     /protein_id="HFG9197113.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            22348..23073
                     /locus_tag="ACGI3L_001400"
     CDS             22348..23073
                     /locus_tag="ACGI3L_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HFG9197114.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKEVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            23086..23358
                     /locus_tag="ACGI3L_001401"
     CDS             23086..23358
                     /locus_tag="ACGI3L_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HFG9197115.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            23351..23902
                     /locus_tag="ACGI3L_001402"
     CDS             23351..23902
                     /locus_tag="ACGI3L_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HFG9197116.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            23914..25005
                     /gene="eutH"
                     /locus_tag="ACGI3L_001403"
     CDS             23914..25005
                     /gene="eutH"
                     /locus_tag="ACGI3L_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HFG9197117.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            25007..25480
                     /locus_tag="ACGI3L_001404"
     CDS             25007..25480
                     /locus_tag="ACGI3L_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9197118.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(25600..25695)
                     /locus_tag="ACGI3L_001405"
     CDS             complement(25600..25695)
                     /locus_tag="ACGI3L_001405"
                     /inference="COORDINATES: protein motif:HMM:NF012392.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197119.1"
                     /translation="MGYPNVEHFIRLFNKKYNMSPSKYRKNTSKI"
     gene            25996..26517
                     /locus_tag="ACGI3L_001406"
     CDS             25996..26517
                     /locus_tag="ACGI3L_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9197120.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            26896..28071
                     /locus_tag="ACGI3L_001407"
     CDS             26896..28071
                     /locus_tag="ACGI3L_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9197121.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            28106..29644
                     /locus_tag="ACGI3L_001408"
     CDS             28106..29644
                     /locus_tag="ACGI3L_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HFG9197122.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            29676..30878
                     /locus_tag="ACGI3L_001409"
     CDS             29676..30878
                     /locus_tag="ACGI3L_001409"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9197123.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQKKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(31045..31644)
                     /locus_tag="ACGI3L_001410"
     CDS             complement(31045..31644)
                     /locus_tag="ACGI3L_001410"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197124.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            31814..33172
                     /locus_tag="ACGI3L_001411"
     CDS             31814..33172
                     /locus_tag="ACGI3L_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197125.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            33165..33797
                     /locus_tag="ACGI3L_001412"
     CDS             33165..33797
                     /locus_tag="ACGI3L_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HFG9197126.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            34126..35283
                     /locus_tag="ACGI3L_001413"
     CDS             34126..35283
                     /locus_tag="ACGI3L_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HFG9197127.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(35430..36065)
                     /gene="lexA"
                     /locus_tag="ACGI3L_001414"
     CDS             complement(35430..36065)
                     /gene="lexA"
                     /locus_tag="ACGI3L_001414"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFG9197128.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(36169..37296)
                     /locus_tag="ACGI3L_001415"
     CDS             complement(36169..37296)
                     /locus_tag="ACGI3L_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9197129.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(37607..38452)
                     /locus_tag="ACGI3L_001416"
     CDS             complement(37607..38452)
                     /locus_tag="ACGI3L_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197130.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(38482..38853)
                     /locus_tag="ACGI3L_001417"
     CDS             complement(38482..38853)
                     /locus_tag="ACGI3L_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFG9197131.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(39006..39266)
                     /locus_tag="ACGI3L_001418"
     CDS             complement(39006..39266)
                     /locus_tag="ACGI3L_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HFG9197132.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(39455..40399)
                     /locus_tag="ACGI3L_001419"
     CDS             complement(39455..40399)
                     /locus_tag="ACGI3L_001419"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HFG9197133.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(40420..41274)
                     /gene="accD"
                     /locus_tag="ACGI3L_001420"
     CDS             complement(40420..41274)
                     /gene="accD"
                     /locus_tag="ACGI3L_001420"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFG9197134.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(41289..42650)
                     /gene="accC"
                     /locus_tag="ACGI3L_001421"
     CDS             complement(41289..42650)
                     /gene="accC"
                     /locus_tag="ACGI3L_001421"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFG9197135.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(42666..43118)
                     /gene="accB"
                     /locus_tag="ACGI3L_001422"
     CDS             complement(42666..43118)
                     /gene="accB"
                     /locus_tag="ACGI3L_001422"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFG9197136.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(43388..43834)
                     /locus_tag="ACGI3L_001423"
     CDS             complement(43388..43834)
                     /locus_tag="ACGI3L_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197137.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            44109..44387
                     /locus_tag="ACGI3L_001424"
     CDS             44109..44387
                     /locus_tag="ACGI3L_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197138.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     ILVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(44516..45247)
                     /locus_tag="ACGI3L_001425"
     CDS             complement(44516..45247)
                     /locus_tag="ACGI3L_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197139.1"
                     /translation="MNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDANLRAVV
                     KRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEVPKEAL
                     SLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHNVDIAK
                     GESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGNKTGKA
                     VVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(45391..46035)
                     /gene="trmB"
                     /locus_tag="ACGI3L_001426"
     CDS             complement(45391..46035)
                     /gene="trmB"
                     /locus_tag="ACGI3L_001426"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFG9197140.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(46173..46493)
                     /locus_tag="ACGI3L_001427"
     CDS             complement(46173..46493)
                     /locus_tag="ACGI3L_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HFG9197141.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(46946..47194)
                     /locus_tag="ACGI3L_001428"
     CDS             complement(46946..47194)
                     /locus_tag="ACGI3L_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9197142.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVKDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(47225..47686)
                     /locus_tag="ACGI3L_001429"
     CDS             complement(47225..47686)
                     /locus_tag="ACGI3L_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9197143.1"
                     /translation="MKFGGVLLIVKDINKSKKFFEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQV"
     gene            complement(47724..48557)
                     /locus_tag="ACGI3L_001430"
     CDS             complement(47724..48557)
                     /locus_tag="ACGI3L_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197144.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSWMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(48831..49517)
                     /locus_tag="ACGI3L_001431"
     CDS             complement(48831..49517)
                     /locus_tag="ACGI3L_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197145.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(49532..52009)
                     /locus_tag="ACGI3L_001432"
     CDS             complement(49532..52009)
                     /locus_tag="ACGI3L_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9197146.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNTIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGNMNEEFIEDVRHMEGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGVTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(52228..53631)
                     /locus_tag="ACGI3L_001433"
     CDS             complement(52228..53631)
                     /locus_tag="ACGI3L_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9197147.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHVTLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            54130..54990
                     /locus_tag="ACGI3L_001434"
     CDS             54130..54990
                     /locus_tag="ACGI3L_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9197148.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(55229..55786)
                     /locus_tag="ACGI3L_001435"
     CDS             complement(55229..55786)
                     /locus_tag="ACGI3L_001435"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9197149.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(55976..56863)
                     /locus_tag="ACGI3L_001436"
     CDS             complement(55976..56863)
                     /locus_tag="ACGI3L_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9197150.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
BASE COUNT        21258 a         7717 c         8259 g        19653 t
ORIGIN      
        1 aagtcacctg aatatatagg aagtcatcct aaaaaacctg gaaaaagtgt ggagtttata
       61 aaaaaaattg atgattatat tttagtagct acagaattag atacaaaaaa aggatattta
      121 tatgtatctt caatgtatgc tataaaagaa gcaaaattag aaagtagagt aaacagtgga
      181 agagtaaaac aatataatgg ttaacataat attattaatt ttccctaaaa tattgaaaaa
      241 tattattata taagttataa tattaatata cacgtagata tttattagtt agatttgagg
      301 ttggaaaagg cacccaatac gctactatag agtagttaat agagatgcag gatacgccgc
      361 cctgccaaat ctaattaaat taaaaagaga ggattaattc ctctcttatt gtttttttga
      421 gatactaatt taatctataa tagaaagatt gaaggtcgtt tatacaaaaa aattttcagt
      481 tatatacatt aaactaatta aataagatat ttataatcta tatgtgatac atattatata
      541 ttaataaaag aaaaatatat agaaaatcct tataaaaatt taaattgtaa tgaataggaa
      601 gtaattaaaa agaattttta ttgattttta aaaatttagt tagaaactat atcattatgg
      661 taaaaaatgt attataatgt ttagaaatat tataataagg agcgattaaa catgaatcta
      721 tcgaagaaaa tagaagataa aagaaaagct aaacagagag ctgaaaaagt taagaaagct
      781 aaaattgcta cagctggtgt ggtattagga gctgttactg gtgcagtgag tggagtactt
      841 ttggctccta aatctggaaa agaaacaaga gaggatataa aagatgcttc acaacaaatt
      901 gctgaaaaga taaatatgaa aactgtagat gtaaaaggca aagtatctga gaagctagag
      961 gataaaaaag gaaactttat agaatcaaag aaaaaaataa aaaaatatat agataacaaa
     1021 aagagtgttg aaaattctag tgaggaagat aaaataatag atatagttga accagttagt
     1081 gttactgagg aataatatgg acaatacaat aacgattaac ataagtataa tatatgtatt
     1141 attagctata cttgcttgta ttgctttagt ttatttaatt attgtacttg ttaaactaca
     1201 taagatttta aataatgttg gaactatgtt aaatgaaaat actcaaaata taaatacaac
     1261 tttaaataat cttcctaatg ttgtagaaac ttttggagaa gtaggagaaa atatgaaaga
     1321 tgtaacagaa gtagttactg aagttacagc agattttctt gttactaaag acagtgtcaa
     1381 atcaaatatg gatgttatag ttgatatatt gactataatt aaaaacattt ttctagataa
     1441 aaaataataa gtttaattaa aataagccta taagatataa tttaaacgac cttaaaatag
     1501 catttataag gtcgtttttt attagcttga tttgacacta tgtgttttta ataattggta
     1561 atattcctct ttatcatttg aacatatata tctatgcttg ttgtttcaat tacatccata
     1621 agaacatctt tacattcaag ctcaaaatct tccattcctt ctaaatattc atcatcttca
     1681 tcaaaaaaga tataagaatt atatagccat tcttcaaatt tttcttcaag tatatcccaa
     1741 tacgaactcc aaaataatcc acaacctgat atataagatg ctctactttg atttatataa
     1801 acctcctcta gaagcttttg taatctactg ctataaagaa aatctgctct tccactgctt
     1861 gatattaatt catttaaatc ttctattgac attaattcaa ctttaccact tttatcataa
     1921 ggagtataat tttcatcaac ccatttatgt ggtttgtttt ctctgcatac tgttgctatc
     1981 aactctacaa cttttgttct tatcattttt ttatcctaac ttatttattt tttataaaat
     2041 aatcatgatt ttataattta tctatttctt gtaatgctaa tttaacagtt tcatatctat
     2101 cagcaccatt tattactaca tcacctttta caagtttatt agcttctcca cctacaacat
     2161 aaaccttttt acctaaacct tgcttataac tagacgcttc aattattaaa gaatctttca
     2221 attgccaatg taaaatctga gcagccactt tatcagcatc acctgtataa acgattacat
     2281 tttcatacac tttattttcc cctccctctt gagaatttga tatagatttg tttagtatac
     2341 cttctgctat caatttagca actttatctt tattattaac ataataatct gtatctgctt
     2401 tactatctac aaaacatact tctattaata ttgctggtgc aatagtatga ttaagccaat
     2461 aaagacctct aacatcagac tttgcgcccc tatctttgaa tactgtagct aacctagtat
     2521 tcactctttc tgcataggtt ttgccattat tagtcttata tattgtttct gtccctactg
     2581 gagttgaagt tgtggcattt gaattaaaat gaatctgaac agccaaatca gtttcctgtt
     2641 tatttgctat agcacattgg tctgctaaat gattacttga ttcatcaact cttcctgtat
     2701 aaacagtagc tccacctatt ttaagccatt taacaattaa gtcattcagt attcttgttt
     2761 ctttgctttc gtttatatac ccaacagctc ctgtaccttt tccaattaaa gtgtgccctg
     2821 gtattattac tactttcaaa ctaacatctc ctttacaatt aaatttaact tctatttaat
     2881 atatgcataa cctagaattt tgtttctttt tatatcttat acttttatta taacccattt
     2941 tgtaaaaata tagaatatta agtaaataat gttaaaatta taattttgta tataagacat
     3001 tacttgattg caataatttt atagcatatt catctattct atatccagtt ctataatata
     3061 tatgtttaat tccagcttga attatagcct tagtacaatt taagcaagga aagtgagtta
     3121 cataaataga gcaattttta actgaaatac cttcttttgc acaataataa agggcatttt
     3181 gttcagcgtg aatggttcta atacaatgtc catctctcat ttcatgacca acttcactac
     3241 aatgcttatc tccagaaata ctaccattat atccagtaga cactattctg ttttctgaat
     3301 tgacaattat agctcctaca taagctctat cacaagttcc tctttcagct actgtttcgc
     3361 acagtctcat aaaatattct tgccatgagc atctattttc aagtttttta ttcaaattat
     3421 atacctccaa aacttatatc taatatataa gatttatacc ttaaaaataa tattaaaaac
     3481 aaatttatac gataaataaa atttattaat actgttttta gtctaaatta tttcatttta
     3541 aattaaagtt acaaggaatc taaaattata tatatctttc ttcgtaatat taatgttaca
     3601 atataaaaaa ctgtctcaat aaaatagaga cagttttaca gtcaaagttt ataatacaag
     3661 ttcatatttt tctttaaatt cttttacagc ttcgggccat gccttttgtt ctgtaatacc
     3721 tttttcttta gctattttaa ttgcaatctc tcttatcatt gcagcgcctt ctaatattcc
     3781 catttttaat ctcccttcaa atatcttttt gtatagaata taaatagtgc taagatttat
     3841 tacatgctgc atatacaata tctatacaac acataacttg taaattcctt ttattttcat
     3901 acgtctttaa ccgacatata attatattca ataagtttta aaattatgaa ctcaattata
     3961 attattttta tttttttaga atctaaacac taaaaattgt aggtaaattt gtcttatgcc
     4021 tttataaata tttctacagt tttaattact ggacatatct atttttatta taaaaagcga
     4081 ttaaaaatcg agaatatccg cataaaaact gtatataagc aaaacggtta aaggaaaaag
     4141 aagaaattta cttgaatgtt aaaatgcgtt gcttgaagca atgggcagtt ttgcctataa
     4201 tatcggtaac aactgaaaga aaggtggtta gccctaatgt taagcgaaaa cattaaaaca
     4261 atcaggaagt caaaaggact ttcacaacaa gaacttgcta taaaactgaa tgtagtgcga
     4321 caaacaatat ctaaatggga acaaggactg tcagttcccg attctgatat gttgatttcc
     4381 atatcagagg tgcttgaaac gcccgtaagt actttacttg gagaaactat tgttgagtcg
     4441 gaagttgata acttaaaagt gatttctgaa aaattagaga ttataaactt gcaacttgca
     4501 caaagaaaaa acatgagaag aaaaatgttt cattggttat ttattttatt atgtgcagtc
     4561 atattaatag tttttgtggt cttaggggga ctaaatagtc cttacttgga ttggaattat
     4621 accgaccctg aaaccgctgt ttttggagta gcttttcatg cttttgagtg gctatttgtc
     4681 agattagtac cgattgtcct tataggagca attattggaa tctttttgac acgtaagaaa
     4741 atatgaagta actctgcttt ttataataca gcaagcgttc cttaaaagcg tcattctaca
     4801 tggcaatcga ggacgactat gtaaggaaga acctttttga tttccaacta agcgaagtta
     4861 ttgaggacga cagtaagacc aaaaccgcat taagtaaagt acaggaagca agactgctgg
     4921 acttatactc tcatgcgtca gatgcaggaa atgcgaggtc tggtagcatg atttacaacg
     4981 atttgtacaa cgactgctag tagaaataat atggagataa gtattatcta caaagtcaga
     5041 aaagaaatga cttgataatt tactcatgtt ataattattg atgtgaaatt aataaatcga
     5101 aattcctttt ttggatttaa taatactgag taaggaaaaa gtgaattact tttgcaagga
     5161 ggtgttaata tcaggcaagt aaagtctttt gtttttccag ttatatcctt aatattctta
     5221 gaccaaatta gcaaagttct tataggatta ttcttaatgg actttgaaat tgatataatt
     5281 gggaaatttt taagattcaa tcctgttcaa aatacaaatc tctcttatgg gggaaacttt
     5341 attggtattc tatctaattt atgggtattg gtattgttta acattttagt tatattagtt
     5401 attatatctg gatatgcttt ttataaatca aaaaatgaac aaacaagcta ttcagtaaaa
     5461 gtaattatgt cttgtggact tgctggtaca atatgtagct tgatagataa attattttgg
     5521 ggaggaagtt tagatttttt gcagatacca agctttttta ttttcgactt aaaagactgc
     5581 taccttactg ttgcagaaat aatatttgtt gtcataggaa ttttgcataa tagagaaata
     5641 tcaatgaaag aatacatata tttttgctat cgtcagttta aaaaataaat ttagaagata
     5701 aatttaagtt tcaaggtaaa cttatttaat cacagcaaat agttggctta cttaagcttt
     5761 tgggctaaac tgtgagcact aattaagtct ctgatatcta acaaacggag cacaaaaata
     5821 aaaattaaat ataaagcaca gttaattttg attaaaaagt tgactgtctt ttcttttgta
     5881 gaaatttaag cataggtaat aaagaaatga ctgcatttaa gcattatgta tataattgga
     5941 ggcaataaaa agccagcaaa gcccataaaa tagagctgtg ctagcaacat gatgaattat
     6001 aagaagataa tcaaaaactt acgctttatt ttaatttaaa aaaatgatta ctgtaaagaa
     6061 atcatttttt attataatca ctgatacatc aaatattcta aataaaattt ttatttatct
     6121 ggaattgtat attttttcta taatattaac tacagcgtac attgcccaag cacagatagc
     6181 caatacaaat actcccatca ttactaaatc taatttaaat acttgagaac catatactat
     6241 caagtagcct attccatatc ttgaaactaa aaattctcca actattacac ctacccatgc
     6301 cataccaata ttaattttag ttaaatttat taaatttcct gtgtttgcag gtaatatgag
     6361 tttaaataat atttgagatt tagtagctcc aaaacttttt aacatcttaa ttttttcttc
     6421 atctatattc ataaaataat tataagctga aagtatagta acaacaacag aaatcgttac
     6481 agctgttacg acgattcctt ctattccagc acctacccaa actataatta taggagctaa
     6541 agcagtctta ggaagagcat ttaaaactac caaaaatggg tctaatattt ttgataattt
     6601 ttctgaccac caaagagcaa ttgctaccaa aatacctaat acagtaccta taacaagacc
     6661 aagaacagtt tcatatacag atattccaat atgtttaaat aattgaccac taaatgcata
     6721 ttgaataaat aaattgtaaa tatcacttgg tttgctaaat agaaatgtat ttataacatt
     6781 taagtcagct aaaagttccc agattacaat aaaaccaatt aaaattaata gctggtagaa
     6841 taatacattt cttttttctc tttttacacc tttaacatag tttatatatc cttcagatct
     6901 tttattaagc ctcatgtgta tctagctcct tccataatat gtcgaaatac ttttgaaaat
     6961 caggaacttt acgtgttttg agaggcgttt ttgttccatc catgttaagt tcaatatcgt
     7021 aaatattttt tatggtagct ggtcttttag atagtattgc aaccttatct gatatgctta
     7081 ttgcttctgc tatagctaaa aaagtgcaac taattgctta aagaaacaga attatcaact
     7141 tcagcaccca tataaacaat attaagattt cctaaactgc tatcccaaac gatactatta
     7201 ataatagtag ataataacaa tctcttatca tctaaactgg cattatcaac ttcatcatta
     7261 aatctcttca aattactaac aataatatca atattaatac tgtcactact aatattgatg
     7321 ttactagatt ccaaagtatt aatcttatcc tttaaaatac taatctcatt atttaggctc
     7381 tcaatctggg aaactatata atcagaagca gtactaccag tattttttgc aagctctata
     7441 actaaatttt taataagtct ttccttatct aaaatttgat ttttaagtaa attagtctca
     7501 gatttaaaaa tattaaaaac attatcagtc ttaatgttat tactattgaa tgcacttata
     7561 atagactctt ctttacaatt cttaatttta tctataacta aactttcaac taatggacca
     7621 ttaagatttt tacagttgca actatcagac ccaagtgttt ttttagtacc acaaatataa
     7681 taatacttta aatccttgtc agtttttttg cctttatagg taattctcat attagaacca
     7741 catttaccac attttataag accagataaa agagcagttt ttccagttga tatccttgga
     7801 gttttatcac gatttttatc taattgattt tgtacttcaa gccatatttc aggttctatg
     7861 actccatggt gttttgcaat tgctgctatt gagttagatg tatttttagc ataggtaagg
     7921 attccacatt ttctatctgg agtacctaca acatccatac cactattttt aaggtaatct
     7981 aaaatttcat cattagcttt tacatatgct ggatttctaa gtattctaga taaagaacta
     8041 gggtcaaatt tgccaccacg aggacccctt attccattat tatagacata tttatataac
     8101 ttagataagg acctaagttc taaatattta ttgtatatta gctttacaat ctccatttgt
     8161 tcatcattta cttgaagctt atacatactt ctttctttta gattttcatc taagaatgtg
     8221 attttttcac tgttgaatcc atgaggtgta ttgcctccaa gccatctacc actacgggct
     8281 aattcataca tattgtcttt tatacgttct gctattgttt ctctttctaa ttgagcaaat
     8341 acacttgata taaacatcat agctcttccc attggagttg aagtatcaaa ttgttctttg
     8401 atagatataa atgatatgct tagttcattt aatttttcta ttaaagtaga gaagtcagat
     8461 acatttctcg atatcctatc taatctataa caaactaggt aactaaattt cttatctttg
     8521 gcatcctgca tcattttctt aaattgtggt ctatctatat tgctaccact aaatccctca
     8581 tcttcatata tcaaaaaatc ttttacacca atagactttg cataatcaat acataattgt
     8641 atttgatttt ctatagaatc accttttcca gtaaatcttg attttcttga ataaattgca
     8701 gctttcaaaa ttaaaacccc ctataagtta ggatatatat ttgaaactat ttatctacaa
     8761 ccttttaagt aaacttatta gaatgaattt attaattagg taaatttata taattctact
     8821 ttttataata tatgactatt tattttattt ctttactatt caagttctaa atcaataata
     8881 aattttgata tttaattgta tcaggacaaa tctctaattt catagattat taatataaaa
     8941 tcataggtta gtgtgaaaaa gttgaaattt aaatatttta aaagataatt tttttgaact
     9001 aataggtata acaaaaattt atagggggat tgcatatgga aatcaatgtt atagaaattt
     9061 tccctaaaga taaagctaaa cttaataaaa tagaaatgga taaagctagt tggtttgtaa
     9121 atataataag taaaaaatat cctaaagaag ctttaaatga agcatttagt actttagaaa
     9181 aagaattaaa tataagtaaa gctaatacat aagctttgat tattgatttt atatactatt
     9241 ggttttatac gctatgactt gacattatat taatcaaata gtatattttt aaatatagca
     9301 caatgaagtg ttaaaagagc aatggagctc catagataaa gtctatggag cttttttgcg
     9361 tatttaactt aaggaggata ggactttgaa taactttgag attaaaacta gaataaaatt
     9421 tggagaaggc tcactaaaag ctttgcaaga attaaaaaac aaaaatgtac taataataac
     9481 agaccctttt atggtgaaat caaaaacaat agataaaata acatctaatt taataaactc
     9541 aacatatcaa gtttttgaag aaatagtacc agacccacca atagaagtag tagtagcagg
     9601 aatagaagca tttaaatcta taaatccaga cgtaataata gcattaggtg gtggttctgc
     9661 aatagatgca gcaaaatcta taatggactt ttctaaaaaa atattaaaaa ttaacgaagt
     9721 agagtttata gcaataccaa caacaagtgg aacaggttca gaagtaacat catttgctgt
     9781 aataacagat agtcaaaaaa aatgtaagta tccattagtg agtgatgatt tacttccaga
     9841 tatggcaata ctagacccag aacttgtaaa aactgtacca aattttataa cagcagatac
     9901 agggatggat gtattgacac atgctataga agcttacgta tctacaaatt ctaatgactt
     9961 ttcagatgca ctagctgaaa aagctataaa gttagtattt aaatacttaa taaaagcata
    10021 taaagatgga aatgacatag aagctagaga aaaaatgcac aatgcatctt gtttagcagg
    10081 tatggcattt aaccaagcat cacttggcat aaatcattct attgcacatg tattaggtgg
    10141 aaaattccat ataccacatg gaagaacaaa ctctatatta cttcctcatg taatagaata
    10201 taattcatca atagtaggat atactaacac aacttactct gctacagcta aaaaatatgc
    10261 acaaatagca gaattagtag gacttgggag tgctaatata agaatatctg ttagaaattt
    10321 agtaaatgaa ataaagaaac tacaaaaaga aatgaatatg ccaactaaat tgacacaatg
    10381 caaattaagt ttagaagata taactaatga agaaagagaa atagcaaaac ttgctataaa
    10441 agatacttgt acattaacta atcctaaggt accaactgaa gatgatataa taaacatatt
    10501 aaagaacatt aaataactac attttattac atgtaaatat aatattatac aaatagggaa
    10561 aatgttttta aaaatataaa ttatatattg acaaatataa aacataaaac tataatgaaa
    10621 gtatcacaaa ggcgtgatac tttagtagaa agcaatggag cttcttagga atattaatat
    10681 tattcttatg gagctccttt tattttaatc aaatagcttt ttaataaact atattcaaag
    10741 aaagcaggga ataaatttga ctgaagaatc taagcaaaga gttattcaag aatatgttcc
    10801 tggaaaacag gttacattag cacatatcat agctaaccct aatgaagata tatataagaa
    10861 gttaggatta gtacttgata aaaaagatgc aataggaata cttacaataa caccaagtga
    10921 agcgtcaata atagcagcag atgttgctac aaaggcttca aatgtatctt taggttttat
    10981 agatagattt agtggttcag tagtaatatc aggtgatgta agttctgtag aatcagcgtt
    11041 aaatgatgtt ttagaagtct taggaaatat gttaaacttc tcatctacaa aaatcacaag
    11101 gacataataa tacaatgaag aatataatat ttatgggaaa gacaggtagt ggtaaaacta
    11161 ccttatgtca aaaactagac cagttagaat taaagtataa aaaaactcaa tcagtggaac
    11221 tttataataa tgcaatagac actcctggtg agtatatgga aaatagaaac ctatataatg
    11281 ccttaataac aacatcagca gatgctaaaa ttatagcaat agtgtatgat gccacacaag
    11341 aagaaaatta tatagcacca ggttttgcca gtatgttttg caaagacgta ataggaatta
    11401 taactaaaat aaataaagct actgaaaacg aagtcaatat agcttatgaa agactatcac
    11461 tagcaggagc aagtcaaatc tttaaaatag acacagttga taatattgga cttgaaaaat
    11521 tatttaaata tctagaaaaa tataaaaata tagatgaagt ttaaggggaa atattttttt
    11581 attcaaaaat attattaaag tatgataaaa taaaaaaatg tataaactat tttaagaaga
    11641 tttaatcttt aagcgaggta ggaacatggg gaaaaaaata ctattggttg atgatgaacc
    11701 actgttaagg atggatacaa aagatatatt agaaagtcat ggctatgaaa taataggcga
    11761 agcaagtgat ggatttgaag ctgttgaaat gtgtaaaaaa cacaaacctg atttagttat
    11821 aatggatata gagatgccaa tacttgatgg tataaaggca ggcaaaataa tatgtaaaga
    11881 aaatatagct ggtggagtac ttttattaac ttcatttgaa gataaagaat acgtagaaaa
    11941 ggctaaaagt ataggtgctt atggatattt agtaaaaaca gcaagtgaaa aatcacttat
    12001 cccaaccata gaaatgtgtt taaataaggt aaatgaattt gaaaaaatga aaaaagattt
    12061 agaaaaagta aattctaaat tgaatgaaag aaaattagta gaaagagcaa aaggtatact
    12121 tataagagag tttaagattt ctgaggatga agcatacact agaataagaa aattaagtat
    12181 ggataaaaga actacaatga tggaaattgc caaaatgatt ataataggat acgatgacta
    12241 atacgataaa aaaaatatca actgcacaaa catacttaaa taataacgaa attgaaaaaa
    12301 ttatagaagt atcaaaatcc ttagatttaa tggcttcttt ttatgaagct gatgttttta
    12361 tagatgtact aagtaaattt gatgatgaag caattgttgt ggcacatggt agacctaaag
    12421 aaaagtcaat gtactgtgaa aatgttatag gtaaaaaggc tttaattgaa aatgaaccag
    12481 gagttataaa gtgcttaaaa acaggagaaa gagtaagaga tattaaagct ttaacacagg
    12541 aatataaact ggtcaaacaa aatattcagc caataacact agatgacaaa gttttagcag
    12601 tactaatagt tgaaaaagat ataagtagtg aagttaagaa tgagtttaat gctagtgaag
    12661 acgaagaaaa taaaaattta catcagttta taaaacttat tggaaataat gactttttag
    12721 ttgataattt aaattcagcc atattaatat ttgataaaaa tggaaaatta aaaattaaaa
    12781 atcgtattgc aactgagata tacaaaaatc ttgggtttgg atatgatata caagatatgc
    12841 attacaatga tttagatata gaaaccaaca cctttgaaaa tatattaatg gatgaaaatt
    12901 atgatgagac aaatgaagtt tcaataggta atatgttttt taaaataaag accatataca
    12961 tcaaagatga tgaatttaag gtttgcaaaa tagtacaaga tataagtgat ttaaagagaa
    13021 aagaagaaga attagttttg aaaacagtgg ctataagaga agctcatcat agagtaaaaa
    13081 ataatcttca tacagtaata tctataataa aaaaacaaag tagattatct caaaatgatg
    13141 aagtaaagca gtgtttagat aacataataa atagggtatt tgcaatactt tcgactcatt
    13201 atttactatc taaagaagtt gataataata tatctatacg agaaggtatc aatttattag
    13261 tgtcaaatat tcaaggtggc tatttattta gtaaggatat agatatacgt ataactggtg
    13321 aagattttaa aattagtgga gaaaaagcaa cagcaatact tttggttata aatgaaatac
    13381 tacaaaattg ttatgaccat gcattttcgg atagagaaca tggtactata caaatattaa
    13441 taaataaaga taacgactat agaaatattg ctattataga tgatggaatt ggatttgata
    13501 gtaataatat aaataaaaat agcttaggga catatataat agatagttat ataacacaga
    13561 tgttaaaagg aaatatagag agaaaaagta gtgagaatgg tacagaagta ttaattacta
    13621 tacctacaca aattaatatt taaataataa ctcatctaca aagtagtagt tttaattgag
    13681 caaagaggct taaggttatt aatagattaa gttaattgaa tgtatttata aaaattataa
    13741 gtatatattc aatttaacag gtatttatta taactttaag cctctttgct tgtttaagac
    13801 atacttaaat tttaggaggt gagaaaatga gagaagagtt attaagtgtt ggtattgaca
    13861 ttggaacaag tactactcag ttaatttttt ctaaattaat agtagaaaat actgaatcaa
    13921 atttttcggt acctagaata agtatagtag acaaagaaat tatttataaa agcaaagttt
    13981 atttcacccc tcttatttca aataatgaaa taaatggtca acaaataaaa gatatagttg
    14041 aaaatgaata taaaaaagca aatatatcta aagaagatat acatacagga gcagtaataa
    14101 taactggtga aacagctaga aaagaaaatg caaatgatgt acttcatact ttgagtggat
    14161 ttgctgggga cttcgttgtt gcaacagcag gacctgattt agaaagtata atatcaggaa
    14221 aaggagctgg agctcatatt tattcaaaag aacattcaac tacaattgta aatatagaca
    14281 taggtggggg aactagtaac atagcctcat ttaaaagggg agaagtaacc gatactgggt
    14341 gtttggatat aggtggaagg cttgtaaaga tagataaaat aagtaaaaaa ataacttata
    14401 tatcacctaa aatagataaa atcataaaag ataataattt aaatcttcaa gtaggcacaa
    14461 tggctactgt agaaaataca aagccaatag tggatataat ggttgactta ttaatggaaa
    14521 gcataggatt aaagaaacag acacctttgt ttgattttat aataaccaat aaatcaataa
    14581 gtatagatga aaatattaaa aatgtttcat tctctggtgg agtagctgat tatatttact
    14641 atgatggaga aataaaagat tattttgaat atggtgactt gggaatttta cttgggcaag
    14701 caataaaaaa ttgtgaatac cttaaaaaag taaatgtagt taaatctatg gaaacaataa
    14761 gagccacagt ggttggagca ggttctcata ctactgaagt aagtggaagt acaataactt
    14821 acactagcga aaagtttcca cttaagaact tgccagtttt aaaattatca attgatgaag
    14881 aaacaggcac ttcaaaacaa atcagtgaag ctataaaaaa taaacttaat tggtttaaac
    14941 tagaaaatga tttacagaaa gttgctatag ccatgatagg aaagaaaaat ccaacctttt
    15001 tagatataca agagtatgct aaagggtttg tagatggaat gcaacaaatc atagaaaatg
    15061 atttaccttt tatagtaatt gttgaaaatg atatggcaaa agtgttaggt caagcaatat
    15121 atgcattatt aaattatgaa aaagaaattg tttgtataga cagtgtcaag gttgaaaatg
    15181 gagactatat cgacattgga aaacctatag ttgaaggtaa agttttacct gtggtaataa
    15241 aaacattagt ttttaattaa tagaaggagg taagtaaatg attttaaata caaaattatt
    15301 tggacgtact tatcagttta aaggcttata tgatgtaatg gctaaagcta atgaagaaaa
    15361 atcaggagat aaattagcag gtcttgcagc agaatcagct gaagaaagaa tagcagcaaa
    15421 agttgtttta tcacacataa aattggagga tataagaaat aatcctgcag tggcatatga
    15481 agaagatgaa gtaacaagaa taatacaaga tgctgtaaat gaaaaagttt atgaagaaat
    15541 aaaaaattgg acagtctctg aacttagaga atggctattg gattcaaata ctacaagtct
    15601 tgatataaga agaatatcaa gaggattaac ttctgaaatg atagcagcag ttgcaaaatt
    15661 aatgtcaaat atggacttag tttatgcagc taaaaagata aaggttactg ctcactgtaa
    15721 tacaactata ggagaacaag gaacattatc agcaagactt caacctaatc atccaacaga
    15781 cgacccagat ggaatacttg catcacttct tgaaggttta acttttggta taggagatgc
    15841 agtacttgga ttaaatccag ttgatgactc tgttgagagt gttactaaag tattaaaaag
    15901 atttgaagaa gtaaaacaaa aatatcaaat accaactcaa acatgtgtat tggcacacgt
    15961 tactacacaa atggaagcaa taagaaatgg tgctcctgca gatttaatat tccaatctat
    16021 agcaggttct gaaaaaggaa atgaagcatt tggatttaat ggcgacacta tagaagaagc
    16081 tagacagtta gccttaaaac acggtacagc tacaggacct aacgttatgt attttgaaac
    16141 tggacaaggt tcagaattat cttcagaagc acatcatgga atagaccaag ttactatgga
    16201 agctagatgc tatggatttg ctaaaaagta tgaaccattc ttagtaaata cagttgttgg
    16261 gtttatagga cctgagtact tatatgatgc tagagaagtt gtaagagcag gacttgaaga
    16321 ccactttatg ggtaaactac atggcttacc aatgggtgtt gatgtttgtt acactaacca
    16381 tatgaaggct gaccaaaatg atatggaaaa cttagccata ctattaacaa cagcaggatg
    16441 tacgtatttt atgggaatac ctcatggaga tgatgttatg cttaactatc aaacaacagg
    16501 ataccatgaa acagcatcac ttagagaaat gtttggacta acagcaataa aagaatttga
    16561 tgcttggatg gaaaagatgg gattctctaa agatggtaag ttaacagagt tggcgggaga
    16621 cgcatctgta ttattaggat aggaggtatt taatatgaat gagaaggatt taaaagcatt
    16681 ggtagaacaa ttagttggac aaatggttgg agaattagat actaatgttg tgtctgagac
    16741 tgttaaaaag gcaactgaag ttgtagtaga caacaatgct tgtatagatg atataacaga
    16801 agttgatata agaaagcaat tactagtaaa aaatcctaag gatgcagaag cttatttaga
    16861 tatgaaagca aaaacacctg caagattagg tataggaaga gctggtacta gatataaaac
    16921 agaaacagtt ttaagattta gagcagacca tgctgctgca caagatgctg tattctctta
    16981 tgtagatgaa gaatttataa aagaaaataa tatgtttgca gtggaaactt tatgtaaaga
    17041 taaagatgaa tacttaacaa gaccagattt gggaagaaaa ttttctccag aaactataaa
    17101 taatataaaa tctaaatttg gtacaaatca aaaggtttta atattagttg gagatgggct
    17161 tagctcagct gcaatagagg caaatttaaa agactgtgtg ccagctataa aacaggggct
    17221 aaaaatgtat ggtatagatt caagtgaaat tttatttgtt aaacattgta gagttggtgc
    17281 tatggaccac ttaggtgaag aattaggttg tgaagttata tgtatgttgg ttggagaaag
    17341 accaggatta gttactgctg aatcaatgtc agcatatata gcttataagc catatatagg
    17401 aatggcagaa gcaaaaagaa cagttatatc aaatattcac aaaggtggaa caactgcagt
    17461 tgaagcaggt gctcatatag ctgaacttat aaaaactatg ttagataaaa aagcttcagg
    17521 aatagacctt aaataaagtc gagggagtgt agaatatgaa aaatgatgta attcgtccta
    17581 atatactagg aattaaaata atttcaaata taagtccaga aatggcacaa aaactagaat
    17641 taaaatcaca tcacaaaagc ttaggtttaa taactgcaga ctgtgatgat gttacgtata
    17701 cagctcttga cgaagcaact aaagcttcag aagttgatgt tgtatatgca aaatcaatgt
    17761 atgcaggtgc tgcaaatgct tcaacaaaac ttgctggtga agtattagga ataatagcag
    17821 gtccaagccc agcagaagta agaagtggtc taaatgcagt agttgatttt ctagagtatg
    17881 gagcaacttt tataagtgca aatgatgatg attcaatagc atactatgct cactgcgtat
    17941 caagaacagg tacatacctt tcagaggtag caggaataag agaaggtgaa gcattagctt
    18001 atttagtagc accaccactt gaagcaatgt atgcactaga tgcagcaatg aaagctgcag
    18061 atgttaagat gtgtgaatta tttgcacctc caactgaaac aaactttggt ggagcattac
    18121 ttacaggttc tcaatcggct tgtaaagcag catgtgatgc atttgcagaa gcagtaaaat
    18181 cagttgcaga caatccaaca ggattttaag gatagttaga tggatgctat aggcttaata
    18241 gaagtaatag gatatgttgc tgcaatagaa gcttctgatg cttgtttaaa atctgcaaat
    18301 gttaatattg taagagttga taaggttgga gcaggtattg ttactttaac aatatgtgga
    18361 gatgtcggtg ctgtaaaagc tgctttagaa gcaggtgaaa tagcagcttc cagagttggt
    18421 acattaagaa catcacatat tataccgaga atccataatg aagtaacaaa tgctttattc
    18481 aaaactaaag aacctaaagt ctgtgaagtt tcagaagata aagaaaaaaa ctttgagatt
    18541 acattggaaa tagctgataa tgtatcgaaa aatttatcag aaaaagaaaa tgtaatttta
    18601 gatgtcaatg aaaacagtgg agatactgaa aatttatata gtgatataga taaaacaaac
    18661 aaaaaaattg aaacagttga tgatagttta acagaagcta atgaggaaaa aatagaaaac
    18721 actaatgata aagaagtatt ggaacaagtt aaaatagaaa attccgattt tgatagagat
    18781 gacctatcaa agaacagtgt aaaaaaactt aaagctatgg ctaagaaatt agattcttca
    18841 ataacttata aagacttaaa tgttcttaaa aaagaagaat taataaactt agttaaaaag
    18901 cttagtagaa gggatagata gttatgacac ttttagataa agatttagta tctatacaag
    18961 aagtaagaac tcttgtaaga agatctaaag tggctcaaga gaaactttct aaaatgagtc
    19021 aagagcaaat agataaaata gtaaaagctg ttgtagatgc agcatttaat aatgctacta
    19081 aattagctaa aatggcaaat gaagaaactg gatttggaaa atgggaagat aaagtaatta
    19141 aaaatacttt tgcatctatg ggagtttatg aaactttaaa gaacacaaaa actattggaa
    19201 taattggtga agataaagaa gccaatacga tagatatagc tacaccagtt ggagttgttg
    19261 caggtcttat accttcaaca aacccaacat caacagtaat atacaaaact ataatatctc
    19321 taaaagcagg aaatactata gttttctctc cacatccaaa tgcaaaaaac tgcatacttg
    19381 aaacagttaa tataataagt gatgctgcta taaaggctgg agctccagag gattcaatat
    19441 tatgtataac taatccaagt atagttggaa ccaatgaatt gatgaaacat aaagatacaa
    19501 acttaatact agcaactgga ggagaagcaa tggttagagc tgcttactct tcaggaacac
    19561 cagctattgg agttggacca ggaaatggac cagcatttat agataaatca gcaaatgtta
    19621 aattagcaat caaaagaata atagattcta aaacttttga taatggtgtt atatgtgcat
    19681 cagaacaatc tatagtaata gaaaaatcta tggaagaaac tgttttaaaa gagcttaaaa
    19741 atcaaggtgc atatgtttta aatgaggagg aaagtgaaag attagcaaaa ttcatattaa
    19801 gagctaatgg tactatgaat ccacaaatag ttggtaaaag tgttgaggta atagcaaatt
    19861 tagcagactt aacaaatgta cctaaaaata caaaagttct agttgcaaga gaaaataaag
    19921 ttggtcacaa tgtagcctat tcaagagaaa aacttacacc aatactagcg ttctatgttg
    19981 aagaaaatgt agaagctatt atgaacagat gcagagaaat attgttaaat gaaggtgcag
    20041 gtcatacatt ctcaatgcat gtaaatgatg aagaattggt aaaaagattt gcccttaata
    20101 tgccagtatc aagaatactt gtgaatactc cttcagcact tggaggaata ggtgcatcaa
    20161 caaaccttgt accagcacta acacttggtt gtggtgcaat aggtggaagt tcaacttcaa
    20221 acaatatagg accacttgat ttaataaatg ttaaaagagt agcttatgga atcaaagaaa
    20281 tagaagaact tggaagagat aaatctcaag ttgaaaaatc aatgtttgac tcaatggata
    20341 aagaagaatt aataaatctt cttgttcaaa aactagtcaa agaactagca taactaaaat
    20401 aaacaatgaa acttatggct atcgctataa atttctaaaa atataaacta taaaaaacta
    20461 taaaattaaa tttttggagg ataagattat ggcaagtgca aacgcattag gaatgataga
    20521 aactaaagga ttagtaggag caatagaagc agcagatgca atggttaaag ctgcaaatgt
    20581 acaattagta ggaaaagagc aagtaggtgg aggattagtt actgtaatgg taagaggaga
    20641 tgttggagct gttaaagctg ctacagatgc aggagctgcc gctgccgaga gagttggaga
    20701 actaatatca gttcatgtta taccaagacc acactttgaa gtagatgcta tattaccaaa
    20761 ggtatcagct gagtaatata agaataatta taaaatttaa attttgattg aaaaagaggc
    20821 tatctcaaaa atgagtctta ctaataaact caatgtattt tgaggtagtc ttttttatac
    20881 atctaatagg agatgtgata aaatgggtgt tttaacagaa aacgaagtaa aaagaaaaat
    20941 tggaaaaaac aaaaataata taactgaatt ttatatagaa aaaggtcaaa taataactcc
    21001 ttctgcaaaa tcttatttag ctgagagaag tattgagctt aaatatgttg ataaactttc
    21061 agatgtaaac aatgaaccta aagaagttgt aaaagaagta gttaaagaga aaaaatatag
    21121 atatactact gtatttggcg ctaaattgga tgaaaaacca gaacatatga ctcaattaaa
    21181 tggaaatctt ttagttttta aagaccataa aagaataata ttgagaggaa aaatagattc
    21241 tcttgaatca gaaatactaa aggtacagat actttgtcag aaactagata tgccaaagct
    21301 tgttaaggaa ttgcaagaag tattagactt tgtaagaaat ataatgagat gtgaagtttt
    21361 agatgaaaag ctaggggact ttaaactttt aggattaact cctcaagaac ttagagaaca
    21421 atctcactat cctaaaaaat actttggtat aggacatgag ttcccaagtt atgaaatggg
    21481 agaagtagta gtagctataa atagtataag aagtaataca cgagaggttg aacttgcagc
    21541 ctatgaagca tttaagggtg agtatggaaa tgttcacaga gaagatttaa taaaggcact
    21601 taatagatta tcgtcagtat tttggataat gatatataag gttagaacta ataagtataa
    21661 gtagttggag gacataatgg agaatctatt aaatgaaata gtggaagaag taataactag
    21721 agttaaaaaa gaagcattta tagaagttga agcatcagga agacacgttc acttaagtag
    21781 agaagatgtc gataaattat ttggagaagg atatactctt acaaaactaa aagacctatc
    21841 tcaaccaggt caatatgcat gtaaggaaag agttacaata actggtccta aaggaagtat
    21901 aaaaaatgta gttgtacttg gaccatgtag aaatgaaact caggtagaaa tatctttaac
    21961 agatggttca actcttggac taaaagctcc tataaaacaa agtggagact tagaaggtac
    22021 tttaagtatt aaaatatcaa cacaatatgg tgaagttgaa cttgataagg ggttaatggt
    22081 tgctaaaaga catatacaca tgactcctaa agatgctgaa aaattcaatg tatgtgataa
    22141 agagatagtt gaagctaagg tgatgggtca aagaccttta acatttgatg atgtagtaat
    22201 aagagtgagt gacagtttta aaacttatat gcatatagac tatgatgaag ccaatgcatg
    22261 tggttattca aaaggaactg ttgctaaaat aataaagaaa gcgtaaattt aacctactat
    22321 ataaattacc tctagggagg atttaatatg aattatgata accttgtaga tttaataacg
    22381 gaagaaatct ataaaaaaat aaatagtaat gaaataaaaa tatctaataa acctaaagct
    22441 gtgattgtat ttgaacaaga taacaataaa tttaacttat taaaagatga atttgaaata
    22501 gtagaatttg ataaaagtat aagggaatgt gaaatagtga tagtttcaag actttgtatg
    22561 agggggctat cgaatatagc acttggaaat tcaacaagtg atgaagaaag atttatacta
    22621 aaaatgatta tgaagggcaa agaagtatat gtcctagatg aaggaattga atacaaaaaa
    22681 tataaggata ctgcaccaaa agcattatat aagaaattta tgtcatttga agatgaaata
    22741 tgtaaatttg gtgtagaaat tataaaagac ttaaatgtta taactaaaaa taagttaaat
    22801 ataaagaaag aactagaaag tactagaggt tctaaaaaag aagatacaaa agttttagat
    22861 aaagatgttt taaatttaac cagtgtagaa agtgtaaaaa tagataatga atttagttta
    22921 gatttaagga ataaaaaact tatatcggaa gctgacttaa gaaaaccaac tataaatgga
    22981 gttaaaaaca tattagttaa taaaaaaagt ataataacac cattagctgt agattttatg
    23041 agaatacacc atctcaaact aaagaaagtg taaggaggta attttatgga tataggaaaa
    23101 gttgtaggta atgtttgggc tacaagaaaa gatgaaaaat tatgtggcca aaaactttta
    23161 gttgtaaaaa ttttaaaaac taaagacaca tacaaggaag gcttcatggt tgcagccgat
    23221 aatgcaggag caggaaatgg agacttagtt cttatatcca aaggttcctc agctagagag
    23281 tcgattgaaa aatctcatgt tccggtagat gcaactatag ttggagtagt cgattcgttt
    23341 gaggtgtttg atgaataaaa gtataggagc tatagagttt aaaagcattg ctaaaggtat
    23401 agaagtatcc aatgaaatga taaagaaatc ttcagttgat gtattgtact taaaaagtat
    23461 ttgcccaggt aaatttctaa taatagtagg tggagaaact tcttatataa atgaatgtgt
    23521 agattatgga ataaaacttg gagaaggata tattgtagat aacttcgtaa taaatgcaat
    23581 ttcacaagaa atattagatg gatttaaaaa taagtatcaa aagctagata gtatagtctc
    23641 tataggcgtt gttgaaagta gtaaagtatg cgctggaata aaaatgcttg ataagacttt
    23701 aaaatctggc gacttagtat tagtaaaact tcaattatct tttgctatag gtggcaaatt
    23761 agtatatata gtagcaggag atttaagtag tttagaatat gcattaaaag aaagtgaaaa
    23821 tgtagtaaga gaaaaagaag taatatataa gactgtaata ccatcagtag acagtcaaat
    23881 aataaaaagt ctaataaaat aatgggggga attatgagta taaacgaaat tataatctat
    23941 gtaatggtag tcttcatggt acttggagct atagataaat gtataggtaa caaatttggt
    24001 cttggagaac aatttgaaga aggtataatg gcaatggggt cacttgcagt tgcaatggtt
    24061 ggtgttatat gtttagcacc agttcttgct gatgtattaa gaccaattgt agtaccagta
    24121 tttaatatac ttggagctga cccagctatg tttgctggaa gtttattagc taatgatatg
    24181 ggtggtgcac cacttgcact tgaacttgcg aaagacccta atgctgggtt atttggtgga
    24241 ttaatagtag gggctatgat gggacctaca atagtattta taataccagt tgcgcttgga
    24301 ataattgaaa aagaagacca aaaattctta gcaacaggaa tacttgcagg tataataaca
    24361 atacctattg gagcattcgt tggtggatta gttgcaggat tcgaggtaat gatggttctt
    24421 agaaacttag tgccaataat aatatttgca gtagttatag cacttggatt attaaaattc
    24481 gaaaatgcta tgataaaagg attcacatac tttggaaaag gtgtagtaat agttataact
    24541 ttaggacttg ctgctgccat agttgaagct ttaacaggaa tagttgtaat acctggaatg
    24601 aaaccaatca gtgaaggtat agaaatagtt ggagatatag caatagtttt agcaggagca
    24661 ttcccattag tgtttgttat aacaaaggta tttaataaac cattaatggc tttaggaaaa
    24721 gttcttggaa tgaatgatgt atcagcagca ggccttgttg caagtttagc taactgtata
    24781 ccaatgtttg gtatgatgaa agatatggac aatagaggaa aaataataaa tgtagcattc
    24841 tctgtatcag cagcattcgt atttggagac cacttaggat ttacggcagg atttaattct
    24901 aatatgataa caccaatgat agttgctaaa ttagttggtg gtataacagc agtattgtta
    24961 gctatggtta tcgcaaataa gacactaaag aaggagaatg tataagatgg atatatcaaa
    25021 tatagataaa aatttaattg aaacattagt aagacaaata atagaagaaa aaataagtgg
    25081 aactaaagac acagtagatt ttgttagaaa taaagacatt agtggaataa cttctataaa
    25141 gttaccaact gtaaaagtta gtgaatctga tagattagat acagggaatc caagtgatgt
    25201 agtttacaca aaagatttat ttacattaga ggaaagccca agattaggtt gtggtatgat
    25261 ggaaatgaaa gaaacaactt ttgattggac tctaaactat gatgaaatag attatgtaat
    25321 agatggaact ttagatataa taatagatgg aagaaaggtt tctgcttctt caggtgaatt
    25381 aatatttata ccaaaaggaa gtaagataca attttctgta cctgattatg ctagatttat
    25441 atatgtaaca tatccggcag attgggcatc tcaaaattaa taaaaatcaa gttaagttaa
    25501 taataatcaa ataaataatt taaaatacaa actcttaaat aagcacacat atttaaaaaa
    25561 gctatgaatt aaaattcata gcttttttta taaagaatgt tatattttag acgtattttt
    25621 tctatattta ctgggagaca tattatattt tttattaaat aatctaataa aatgctctac
    25681 atttggataa ccaatactat tttactgata atcttttcct tatcactaat cttacatttt
    25741 aaaatattat ttttactcgt aatattatca taagaatttg tttcttattt aaaactaatt
    25801 agaattataa agtttattgc catgttatta ataaaataaa tccagttaaa tcgagtgcta
    25861 gttaaagtaa taagaaactt ttacaatggt ttcctttatc gattgaaata aaagttaata
    25921 tggtataata tctaaagaga gaatcttatc aattagaata tgcatagaaa caagtggctt
    25981 aaaaggagac gttatatgga agagatagta aagaaggaac aagcaagtat gaatgatatt
    26041 tttttgtatc ttaaagctaa atcaaactca ttatataaat ttgtaatatt atataatgag
    26101 tttatcaata aacctaaaga ttatggaact ggggaactta taaacatggt tgaagtacat
    26161 atgctaacag cgattgaaga aaatccagga ataagtccaa ctcagttagc taaaatatgg
    26221 aacagaacta aaggtgcaat atctcaaact atatctaaat tggagaaaaa gggttatata
    26281 actaaagaaa agaaagaagg aaatgcaaaa actatattac tatatccaac cacatcagga
    26341 gtagagttaa gtaaggcaca taaactatat gacaccatag atgttacaag aacatttgaa
    26401 tacttaatca aggagtgtac attagaggag atagatagtt tttataaagt aattgatttg
    26461 tttattaatt tattagaaga atctccgcag gaaaataatg attctgaaaa agtgtagctg
    26521 agattgaagt tgaataaaga gaaatagata ttatagaagt agtacttaag tacacattat
    26581 ataaaaatat aataggtata ggattaaaaa gtttagtggt ttaaagttta accactaaac
    26641 ttttttaatg tctataatct actattattt aatttactaa aaataaaaaa actcattata
    26701 ttaagataaa aatagaaaaa taactagaaa aatactataa tatatcagct taatacagaa
    26761 aaaagttaaa aaatttgaga aaaataaaaa tgaaaacgtt ttatattgac atagagaaaa
    26821 agtagtgata ccatttaaat atagtttagt agctaaacta tatttaaatt ataataacta
    26881 ttttaggggg atgttatgaa tttaaaacaa ttaagtgaaa aatacgaaga atatgtaatt
    26941 caaatgagaa gagaatttca taagtatcca gaattatctt ttaaagaaat aagaacaacc
    27001 caaagaataa gggaagaatt acaaaaaata ggggtccctt ttgtatctat tgaaccaaat
    27061 atcgtaatag ctactataca aggcaaaaat gaaggtaaga caattgcaat tagaggagat
    27121 atagatgcgc ttccaatgca agaagattca gatgttgaat acaaatcaga atatgatgga
    27181 ataatgcatt cttgtggaca tgatgctcat ggagctatgt tactaggact tgcacatatg
    27241 ctaaatgata taagaaaaga tttaaaaggt agagtattat tagtttttca agcagctgaa
    27301 gaagttggtg gtggacacaa ggagataata cagtacttta aggaaaatgg aggaccagat
    27361 agattaatag ctactcatgt ttggtccgat attgaagctg gtaaaatttc tgttgaacca
    27421 ggacctcgta tggctggtgg gtctggttgg agaatagaca taacaggtag aggaggtcat
    27481 ggttctagac cagatcaaag catagatcct ataaagccag cttgtgatat agttttaaaa
    27541 gtatcttcta taccagttaa tcatataagt gtactagaac aatgtgttgt acatgcatgt
    27601 gcaatacatg gaggaactac aataggaaat gttattccaa acaatgcaga ggtaataggt
    27661 ggatatagat attttactga agaatcaggc aaaaaagtgt ttgacattat aaagcaaatg
    27721 agtaatggtg ttggacaagt ttatggagtg gatgtgaagg ttactcatac tggaggcata
    27781 ggacctgtta tcaatgatga agaagcagtt aagatggcta aagaaatagt ttctaatata
    27841 gatggattgg agttagattc ttatgagcca atatgtgcat cagattgtta tggtgaaata
    27901 ttaaaagagt attctggctt ttattgttat ctaggggtag gtaacaaaga aaaaggaata
    27961 atatatgcac aacaccatcc taagtacaat atagatgaag atacattaaa gttaggttgc
    28021 gaatttatgg ctaaatatgc agttgaattt ttaaataaaa ataataacta aaataaatcg
    28081 aattttataa atggggggga tgaaaatgca aggtgcatta aaggaaaata agaaaaaaag
    28141 tggtggagga tttttaggat ggattgaaaa agttgggaat aaaatgccac atcctctagc
    28201 attatttaca tatattacat tgatagtagt agcattatct gcaatagcaa gctttttagg
    28261 tttttcagca acaagtcctg ctacaggaaa gttaataaaa gttatgaact taataagtgc
    28321 aaaaggttta gtactattta tgcaagagtt tgttaagaac ttccaaaact tccctgtgct
    28381 tggagtagtt ttagttatgg cagttgccac aggagtttgt gaaaagacag gatttttttc
    28441 aactgccata aaaatgagtt tatcaaaagt taaggggaat gcggttgtat ttataatagc
    28501 ttttatagga gtatttgcta atcaagctgg tgatgctgct tttgtattag taccaactct
    28561 tgcaggagca atattttatg gattaaatag aaatccatta gctggtatat tctgtggatt
    28621 tgcatcagtt ggtggtggat ttgcaacagc tgtaattcct gggggatggg acgttacgct
    28681 aacgccaata actgtatcag ctgctcaaac tattcaacct gcatttgata tgacattatt
    28741 agctagttat tatgcactat ttgtatctgc gtttatagta gctacagtat caacaatagt
    28801 aacggttaaa tttatagaac ctaaattagg taagtatact ggtaaaccag aaggtataga
    28861 tgataatcaa ggttttgagg tcacaaaaga acaagcaaaa gcagcaaagt tagcaggttt
    28921 tacagtttta gcttatgtag cgttattaat tgctttgtgt ataccagcta atagtttttt
    28981 aagaagtcca gaaggttctt taatatttgg agcaccactt atgtcttgct tacagttttt
    29041 tatagtaata ctattcttct tgccagggat tgtgtatgga atgagggttg gtaaaatcaa
    29101 gactgtaaaa gacttaaatg atatattatg tcaatcaatg gcagcaatgg caccgtttat
    29161 cgtacttgca atagttatag gtcaattctt aacgctattc tcagtgtcta atttagcaca
    29221 ggtactagct ataaaaggtg gagcattact caactcattg ccactaccac cacaagctat
    29281 aatactgcta ttcttagtac tagtagcgtt tataaatata tttgttataa gcggaagtac
    29341 aaaatggatg atatttggac cagtatttgt tccaatgtta atgcaattaa acatacatcc
    29401 agcatttact cagtttgtat atagattagg agattctgta accaatcatt tatcaccatt
    29461 aaatgcattc tttataatac ttttagcaac agtccaaaaa tacgataaaa atgcaggtat
    29521 gggaactata ttctcagcta tgatacctta cactataggt tactttgtag tacttgcagt
    29581 tttagtagta gtttggatga caataggtat accagtagga ataggtggac aagtttggtt
    29641 ataaaacata tttaataatt ttgggaggaa agaaaatgga aacaactgaa ataagataca
    29701 attttgatga agtaatagat agaagtggaa caaactgtct taaatatgat cttaagagtc
    29761 aatttatgcc agaatctcca gaagatgcac taccactatg ggtagcagat atggattttg
    29821 catgtgcccc tgagataatt aatgcaatgc atgaaagaat agacagaaaa atatttggat
    29881 atagctctca acaaactgat gattattatg aagctgtatg tggatggttt aagagaagat
    29941 ttgattggaa aatagaaaaa gagaatatat tctttagccc aggggttgtg cctgcgttag
    30001 gatttttcac acaaatatta acacaaaagg gtgatggtat cataatagaa aagcctgtat
    30061 actatccttt tgaagataaa ataactaata atgaaagaaa agtagttaat agtcctttaa
    30121 agtttgaaga tggtcattat tctatggatt atgatggatt tgaagaatta gctaaagatg
    30181 aaaataataa ggtgtttata ttatgtagtc ctcataatcc agttggtaga gtatggaaaa
    30241 aagaagagct tagaaaaata gtagacatat gtaagaaata tgatttgtgg ataatatctg
    30301 atgaaataca ttgtgatatt attcgtaaag gtgaaaagca tataccatta gaagtagcat
    30361 gtcctgatta taaagataga ataataactt gtacagctcc aagtaagagt tttaacttag
    30421 ctggtatgca attatcaaat atagtaatca ataataagga attacaaaaa aaatggatgc
    30481 ttgaaacaga ttctaaatta gctatattcc tacctaatcc attcgcaata gttgctacta
    30541 aagttgctta taatgattgt gaagattgga tgaatcaagt aaatgagtat atagatggta
    30601 atattaaata tgtagaagat tttgttaatg agtatatgcc taaagtaaag ataataaaat
    30661 ctcaaggaac ttacttagtt tggttagact ttagagggta tggattagat gcaaaacagc
    30721 ttgaatatgt aatgcttaac aaggcgaagg tattgctaga tgaaggatac atattcggag
    30781 aagaaggagc aggatttgaa agaataaatg ttgcttcacc tagaacaatt atagaagagt
    30841 gtatgaatag aataaaatgt gcatttgaag gattataata gtaatatcta aataatatat
    30901 ttgtgtattt taaaaaaaga ctatgctaaa aaaatatttc aaagcatagt cttttaaagt
    30961 tttatgatga gtttaaaaaa tttcaaaacg ttactattca cttatatgtt tatattagaa
    31021 ataattccac aatatactca ttttctaaag ttgcactttt atacaccttg cttcaccaat
    31081 atcatgtgta accaaaatag tagacttatt ctcattctta ataatactat aaacatcatc
    31141 acaaactaat aatctagtct gataatcaag agctgaaaaa ggttcatcta aaagtagaat
    31201 atctggattt acagaaagtg ttctaataag cgcaactctt tgtctcatac ctccagataa
    31261 ttcttttgga tacatacttc taaaatccca taatccataa gtctttaaaa ggctttcaac
    31321 tctatctaaa gattttttat cttttttgcc ttgaatttcc aatccaatag ttatattatc
    31381 cattatattt ctccattcaa gcaaattatc tttttgaaac atatatccaa tatttccagt
    31441 aatctttata tcaccactag tcggttttaa aagattagta agaatattta atattgtaga
    31501 tttaccactt ccagaaggac caagcaaagt taatatttct ccttctttca agttaaaatt
    31561 gacatccttt aatacttcaa gctcgccttc cttagtgtag aagttcatat ttatattttt
    31621 aacttctact atgttgtcat tcattatgcc accccctata acttttagct cgtatatatt
    31681 atgttattaa caatatgacc tatttgtacc atttttcata aatataatat aaatattttg
    31741 tttatttacg tattttctta gtaacttgta cgtataaatt atagataaat aaattataag
    31801 gtaggggata aatttgagta acataataac gaatttaata gagtcaatat ttactaatcc
    31861 aataactata ttgtttttac ttgcaataac tgtgtattct gtttttaaaa taatagaaaa
    31921 taacagagta tattcatttg taagttcaaa attagacgaa atcaatagag actataagac
    31981 aagtgagttt tataaaaagg taagggatga ctactataca tatagtaaag aaaatcctta
    32041 tgcagacgta aatataactt catttataga ggaagttgta tctgatttaa agcataataa
    32101 tttgccattg ttagaaaaaa ttagaagtat aaaaaattca tcttcaataa gtatattact
    32161 tggggtttta ggtacgtttg ttggtctttc tacaatgctt ttatgtgttg atactaaaga
    32221 cattataaat tcacttcctt caactattag tagtatgcaa actgcattta caactagtat
    32281 atttggagtt gtattttctc taattatagg ttactttact aagataaaag attgtgaaca
    32341 tgttttgata caaataatgt taaaatctga aaatttacta acatctgaaa taactcattt
    32401 taagtcagaa agaatggatt taaaagtaga agaggtaaaa aatacaataa aacaaataag
    32461 taagtctata gaagctattg aaaaatttga taaaatatct aaagatttaa atgactttaa
    32521 tgatgaattt atcagtggta tagaagcttt aaaaagcctt ttagaaggtt ctcaaagttc
    32581 tattaagaca tttgaccaga gcgtaagaaa attagataaa cagtttaata ttttaaatat
    32641 aaaatttgta aagctttttg ataaatatga taatcaagat aatataaata aagagatttt
    32701 atttgatata aaagaatctt caaaaaatat atacaatgcc actgaaagcc aattcaaaat
    32761 tagagattat ataaaaaata taaatgcagg atttgctcta tatgaaagaa gtgctcaaga
    32821 tttattaact aaattaatga cccatgaaaa taaaatatct caaaatcaaa aaatcctttt
    32881 agatgaaaag tttaccttag atgactcaat aaaaaatctc tcaagtatta ttgaaaactt
    32941 ttctaatgac ctacaagtta aactggatat gatgtttgaa aattctttag atattcaaga
    33001 taagttagat gttatgttta ataactcttt tatgaatgat gaagttcctc ttgatagtga
    33061 agaattattt aaggatgatg ttaataatgt atttaatcct tttagtgaag aaatttatga
    33121 gatagaggat aaagaaataa aggtcatagg tgaggatgag ttaaatgaat aataaatata
    33181 gaagaactgt taacagagaa tttgaaaaga gtagcttttg gccaacattt acagatttat
    33241 tatctactgt attgatggtt gtgattctta tcttatttag ctcagaaagt atttcaggtt
    33301 ctgttgaaca agatttagct aagaatgtca atgcttctgt tgaagaaact tttaaaaaaa
    33361 gtggaatacc tgtgaaggta gataaatcta atgggcaagt aacttttggt gaaaaaacca
    33421 tgtttgatgt agatagtgat gttttaaaac cagaggctaa agaaatgcta aaaatgtttg
    33481 ttccaaagta catagagact atttataaag attatggtga ctatatatcc aaaatagtta
    33541 tagaaggtca tacagatgat gtgggaagtt atatatacaa cttagattta tcgcaaagaa
    33601 gagcatatag cgttgctaaa tttatagtgg gagatgaaat aggtgactat aaatacaaag
    33661 ataaagtgac taagcatatt attgcaatag gaaggtcaaa agctgaactc atcaaaaatg
    33721 gtgacaatag cgtgaataga gatgcatcta gaagagtaga actaaaatac gaaataaata
    33781 ttaatcaaaa taaataatta aatttttata aaaaaaaaga aggcagttgg tgtgagcttt
    33841 aagccttctt taaggaaaaa gtttatttat ttttgttgat acttaacata ttatagtttt
    33901 tagaagcagt ttgcaatata ttaaacgtaa atggtcgttt aaaatgcata actggatact
    33961 actgatgtaa aatatttcat tttatataat ataaaaatta tacagtgtca attttctata
    34021 ttattgtact ataatctatt atttaaaata ttatgtaaaa aaatatcata aaaacgcata
    34081 tcatgttata attactagag tattatgaat atggaggcgt agtttgtgat agaaataagt
    34141 ataaaaaata aaaaaaattc taaaattaaa actttgatac ttttattgat agtatctata
    34201 tcgatttatt taactggttg tactacatca gataatggaa ataatcaatc aaataataat
    34261 gattctttgt ctagtagtat atcaagtgat aagaatgtaa aaattcattt tattgacact
    34321 ggaaatagtg atgcaatatt gattcaagat ggtaaaactt ttacattgat agatggggga
    34381 gataatgatg atgagggatt aatggtagat tacctaaaca atcaaggtgt aaaagatatt
    34441 aaatatctta tagctaccca ttctcatgca gaccatttag gtggacttga ttctgttgtc
    34501 aaaaacttta atatagaaaa tgtttttgta tcgaatggtt cagcagaaac aaagagttat
    34561 agggacttta taaatgcttt agcaaataag ggtttatccc caagtgtacc gcttgaaaat
    34621 aataagttct atttagaaga ttcttatttt gaagttctaa atacaaatgg gggagatact
    34681 actaatgaac aatctctagt ccttgtatat actaatggga atgataaagt tttatttaca
    34741 ggtgatgctg aagaaggtac cgaaaaagaa atactaccta agcttgagaa agtagacctt
    34801 ttaaaagtag ctcatcatgg ttctcgtagt agttcatctc aagagttttt agataaagta
    34861 aatcctgaat atgcggttct tttagtaggc aagggtaatt catatggtca tccacatcag
    34921 gagacaatga ataaattaaa aaaaatggga gtaaaagtgc atagaagtga tgagtgttca
    34981 gatataatat ttgaatcaac aggtgatgga gtatttacaa gttgtaaaga tggaagttat
    35041 aataaaggcg ttagagaaga tggaaactct ggaaaatcaa acagtaatac aagtaaaaat
    35101 gattctttta aaaataaaca aaatacatcc aattcagaag aaatagtgta ttttactcca
    35161 aaaggtaaga gctatcactc tacaaaaaat tgtagtgggc tttcaagaag taaaaaaata
    35221 ttatcaggca caattgcaga aagtaagaaa aatgacccat gtgatatatg ttatggaaaa
    35281 taacaaaaaa acaaccaatt tatctataaa gcttctgaac tttaaatcat ttaaaaaata
    35341 aaataaatgc ataaaaaaat aagctataat caatagataa cacattttat ctatacgaat
    35401 agcttatttt tttaagtatt ttttaatagc tatttaataa ctctaaatac accagttaca
    35461 atacctacaa tttcaacttc tgagtcattg agcataattg gttccataaa atcattttct
    35521 ggctgaagtc ttattaaatt tccttcttta aaaaacctct taaccgtagc agattcacca
    35581 tttataagtg caactactat ctgagaattt aaggctgtat tttttttgtc tactacaacg
    35641 taatcttcat ctaaaattcc tgcattaatc atactttcgc cttttactct taatacaaaa
    35701 ttgttactgc cctttactaa actggcaggg aatggaatgt attcctctat gttttgttga
    35761 gctaaaatgg gttctccagc tgttatttga cctactaaag gaagctctat tatttcttga
    35821 ttagctccag aaacatcatt tactttacta cgttctaaaa cttcaatagc tcttggttta
    35881 gtagggtcct ttcttatgta tcccagtttt tcaagtttat ttagatgaga gtgcacagtt
    35941 gaagtagatc ttaaccctac agcagtacat atttctctta cagcaggtgg ataacctttt
    36001 aatatgattt gagactttat aaattccaat atcaagactt gcttttcagt tagatctaaa
    36061 tacataacat cactcatttc caaacatatt ttgtttttat ttccatacac tttatatttt
    36121 taattataac ataatccatt tatatctgca aacatttgtt cctgattttt aatcgtcctc
    36181 aatccattca aaattcttga ctatatcacg ttttacattt ttcttatgag ctgcataaag
    36241 ctgagtagtt gtgacattat catggtcaag taagttttga acatcatata tagaaaatcc
    36301 tgtttggatt agagaagttg cagccgttgc tcttaattta tggggactat atccattgtc
    36361 tctagtagta tcaagtggaa tagatgtata tttttttacc agtgttctta tagcctttgc
    36421 tgtaattctc ttattttgaa gagacaaaaa taaagcatct ttttcttcat catttaatag
    36481 ttcatctctt gttctttcgt tttgcaaata atcttttatt acatgttcac aagtatgatt
    36541 tataggcatt aaaacttctt tcccacgttt tctatatatt ttaaattcac ctcttgaaaa
    36601 attaaaagag gagatattga gttctctaag ctcatttaat ctaagcccgt atgtaacaaa
    36661 taatgctagt atagctttgt cacgtaattt agtttttctc caatatacct tttctttctc
    36721 tgtaagccct tcacctgttt ctactgattc aagcatctta gcaacttcat ctatctcaag
    36781 gcgcttaata gcatctggct gaggtttagg aagttttatt ggattgaatc catcagttat
    36841 attattatct atctgagagt ttctgtataa gaatttaaat agagtagaga tggatgattt
    36901 ttttcttgct aaagctctat tgttattttc aaaaatcaat gtgttttttt ctgtattttt
    36961 gtaatatcta ctgcaataat cacctaagaa taaatttata tctcttgatt ttattgtatt
    37021 aaaatcatct tctgtaatgt cttttacaca atctgcattt gttaattctt tggtttcaat
    37081 caaatatgaa caaaaaaaat taatatcttc taaataagca agtcgtgtag aaactgcaac
    37141 agaacctttt aaatatataa aataatcctt cataaataca ggaagtttat tttccaaaag
    37201 tagacatttt tctatgagtt cattttcttt gataacaata ttatcaggtt tatctgattt
    37261 attatgtact tttataattt tcttatcatt attcaaaatt aaacctccta aaactaaaat
    37321 ataaatcttt tatattattt tttgatattt atactaagtg agtataaata tttaatttaa
    37381 tcatttttta catttttaag agattagcag tgctttagat gaaattatca ctaactattc
    37441 cctaaatcca catttaaaga ctagttgaat ttaagtactc ttttttattt ctcaatatat
    37501 ttatataaat atattgagaa attttttatg ctctactaga atctttttta tataatattt
    37561 ttatatgttt ctaacgaaac caaatattag taaaatatgt atttatttaa ctaaagtttt
    37621 taaatgggct gactaagctt aaaatatagg atattatgag agttactatt gaaaaaataa
    37681 accctattgc cataaagaaa cttataaata tgttatactt aactattaaa ctggatatat
    37741 tcaagttatc aaatccaaat aagtatgtaa ttgaacttat tacaaaaata actataacta
    37801 taaagctcag gccatttaag ctatttttta aatcagcact actaagtgac atatgtgtag
    37861 atatagaata cattaaaaac ataaatataa aatacttcaa tgaatataca ctaggtgtta
    37921 acaacattat tcttataaaa ttggaaatat cacctaaaat aatgtgtata aaaccattta
    37981 tatttaaatt attaatcatg cttacatata actttaaatc tatattttga gtcactttca
    38041 tataactatc tggcagtaat atcttaaaaa ttaaaataat cattattgtt ccacctataa
    38101 taggtgcaat tcctataaag aaatttccta tactttgata aagattatct tttttatagc
    38161 tatgacttac atatcctagt ataccatcat ttttactttc tattggtctg aaaaacttaa
    38221 ctgaatttat tttatgcatg aaaattaaac acattatcaa atgactcaat tcatgaacaa
    38281 atgttcctat agctccagtt acaataattc cagtttttcc aaaagatgaa aatataaatt
    38341 tattatttag attttctgta atgctaaaaa tcaatccaaa tacaataaat attcctatga
    38401 aacaaaaaat atttattaca cttattttta aaatttcgat tatataaatc ataagttaaa
    38461 tcctcatgta aaagtattta actactctac ttcatatcca ttacagctta aaattttaca
    38521 agcattttct atatcctttt cttttactaa gatatagtct gtatcataag tagaaattgc
    38581 aaatatgctt attttgttgt ctgctaacaa actacttaac ttagataaaa ttcctacaag
    38641 tgaaaagtct aaaggaccta gtatcttaag tattctccac tccttttctg acttaacatc
    38701 agaaggaata ttattattta aacatacaac acttaattca tcatcagttc tagttataga
    38761 gtaaaacttc tctgtatcta tccatgttgg tattttactg tcattattta atctacatac
    38821 tgcatactct tctaccaata attttaattt cataatgtat atttcctcca atcttatttg
    38881 tttacttaag attatacatt aaaagttaca taaaataaaa catataaagt aaaaaaggtt
    38941 cactatagtg tcctatttct atagccaacc tttaaaactt aattaaattc taataaagag
    39001 atatattatc taggttcaat tataagttta atggctgttt tcttatcacc ttcgatttct
    39061 atatcagtaa atgcgggaat gcaaactaaa tccattccac taggtgcaac aaaacctctt
    39121 gctattgcaa ttgattttat cgcttgattt agagctccag ctcctatagc ttgtatttct
    39181 gcaacgcctc gttctcttag tactccagcc aaggctccag ctacagaatt aggattagat
    39241 tttgatgaaa cttttagtac ctccatttca acatctcctt gttaatttgt taaagtatcc
    39301 attacctaaa gtactaaatc ataattgcca tttactaatt acaatcatca tttaaagtat
    39361 acttttataa aaatatactt ctataatcgt tttaagaaaa cctttatttt ttttaaccat
    39421 tttattatga aaaaactaca aatttcttta tattctataa gcattttcca atatttctaa
    39481 attttttata tctttgagct ataatttcct ctttatccat atctttgtaa tgatttaatc
    39541 tttctaaaat gtaagctttt atttcttttg aaacagcttc tacatctttt tgtgctcctc
    39601 caagaggttc ttttataatc ttatctatta tttttaaatc atataaatca ttacttgtaa
    39661 gcttcataac atcacaagct tctttagctt tagatgaatc tttaaataga atactagaaa
    39721 gcccttctgg agaaatcaca gaataaactg aatgttctaa catacataca tcatttccta
    39781 ctccgatacc taaagctcct ccactaccac cttcaccaat tacaaaagtg attactggaa
    39841 cagaaagttt actcatttca agtaagtttc ttgcaatagc ttctccttgt cctctttctt
    39901 ctgcttctag accacaaaaa gctcctgatg tatcaataaa cgttattata ggtctattaa
    39961 atttttcagc ttgtttcata agtcttaatg cttttctgta tccttctgga tgaggcattc
    40021 caaaatttct ttttatattt tcttttgtat ctcttccttt ttggtgtcca actatagtaa
    40081 cattaaactt tcctatctga ccaattcctc caaccataga agggtcatct ttaaaaagcc
    40141 tatctccatg aagttctaaa aaattagaac aaatatgttc tatgtattcc aatgtcgtag
    40201 gtctctttat atctctactt aatgttacct tttcatatgc tgatagatgt gaaaaagcat
    40261 cttccttaag cttttccaat ttctcattaa gtgaatttat tttatcactt aaatctatat
    40321 tatttgcctt agaaatagtt attaattgtt taatatcatt ttctaagact tttatttttt
    40381 cactattatt ttcaatcaaa acagttcctc ctttatgccc tatttcttgt gcatagcaag
    40441 aatttgatat aatacttcct tcatttttct tctatctact atcatgtcaa taaaaccttt
    40501 ttcaagtaaa aactcagaag tttgaaatcc ttcaggaagt ttttgattta ttgtttgctc
    40561 tattactctt ggacctgcaa aacctatcaa cgtatttggc tcagaaatta taatatcacc
    40621 aagcatagca aaactagcag ttactcctcc agtagtaggg tcagttagaa ctgatatata
    40681 tggcaatgat ttttcttcaa gcttagaaag tgcttgagaa gtctttgcca tctgcataag
    40741 agataccata ccttcttgca ttctagctcc tcctgaagca gaacaaataa ttataggtaa
    40801 attattttca gcagcatact ctattgaata agttattttt tccccaacaa tagaacccat
    40861 acttcccatc ataaaatcag gattcattac acaaataact gttttaattc catttattct
    40921 tccataacct gtgacaacag cttctgactc ttttgttttt tccttataag agtctacttt
    40981 ttctttgtat ttaggaaaat ttagtggatt ttgaaattct acatcagaat taaactccat
    41041 aaaagttcct ttatcaatca ataaatttat tctttttctt gctcttaagc cataatgtct
    41101 tgaacatttt ggacatacaa atgaattttc ttctatgtcc tttctaaata catgactatc
    41161 acaacctttg caataggtcc aaaatttatc atctacacta ttctttttaa agttgtcatc
    41221 taaagaaatc gtaacatact tagattcttt tgatgataaa aattttttta tcataatcta
    41281 tttactcctt ataatgtagc aaattctttc ttcataaaga catcttctat aaatttggta
    41341 tgatgagtat cttctctaaa ctcctcactt gttacaagtg ccttttgaaa ttctacattt
    41401 gtattaatac cttctacaat aatttcgtct agagctctat atattctact tatacattct
    41461 tctctagttt cagcccaaca tattaactta cctatcatag aatcatataa aggtggtata
    41521 gtatatcctg catatacaaa agtatcaaat ctaacaccaa aacctccagg taaatttaat
    41581 gattctatct tacctggtga tggagcaaaa ttctttgatg aatcttctgc atttattcta
    41641 cattcaatag catgacctct aaaagtaata tcttcttgtt taaaaggaat tttatcccca
    41701 ttagctatag atatttgaag ttttataagg tcaagatttg ttaccatctc tgtaactgga
    41761 tgttcaactt gtattcttgt attcatctct ataaaataaa agtttttatc tttgtcaact
    41821 ataaactcaa tagtacctgc accgatataa cctactcctt ttactatatc tactgcaatt
    41881 ttatgaagtt tttgtctttc ttcatctgaa aggtatggac ttaaagattc ttctattact
    41941 ttttgatttc gcctttgcat agaacaatct ctatcaccta aatgtattgc atttgaatgt
    42001 ttatctccaa atacttgtac ttctatatgt ctaggatttt ctataaactt ttccatatat
    42061 aaatcactat tagaaaatgc tgctagagct tctgaacttg ccatatcaaa atttgaaaaa
    42121 agttcttctt cttttctaac gattctcata ccttttccac cgcctccact tgaggctttt
    42181 atcataacag gatatccaat ttctcttgca acttctaaag cttcttcctt agttttcaaa
    42241 acagattctg aaccaggaac aacagggata ttcaattcca tcatagtttc tcttgctcta
    42301 gatttatctc ccatcaaaat catttgttct cttgttggac ctataaaaat aatattatta
    42361 tcttcacatt gctttgcaaa ttcaggattc tctgataaaa atccaaagcc tggatgaata
    42421 gcatcacact ttaatttaag agcaagatag attatatttt ctatattatt ataactctta
    42481 cttatattat ttggtcctat acaaatagat tcatcagcta tatatctatg aaaacaatct
    42541 ttatctattt cagaatagat agcaacagtt tttataccta gttctttaca tgttctgatg
    42601 attctaactg ctatatcgcc tctatttgca actagtattt tttttatcaa cttaaatacc
    42661 tcctactaca atggttttat cttaaataaa ggttgattat attctactag ttcttcatta
    42721 ctaactaata cttcaattat ttcaccttta atttcacttg ttatctcatt cataagcttc
    42781 attgcttcta atatacataa agtgtcgcct tcttcaacta catcgccaac tttaacaaag
    42841 ctatctgcat ctggacttgg agaatcatag aatgttccca tcaaaggagc tactactact
    42901 gatagattct cattagatgt gacaggtgta tcgtttacaa ctggcttttc taaagaaaga
    42961 tccactactg attcttgttg tacacttaaa acaggtgaac ttgtagattg agctttttta
    43021 gatacttcta atcttaaatc gctactttca agttttacat attctaagtt agttgagtct
    43081 atggccttta ataattcctt aatttcattg atgttcattt tgttaccccc ttgtattatt
    43141 acctggtgct aatattatat cacaaaaaac aaatttataa aagaaaaagt gctgactaga
    43201 gaatcaacac atcaatatat cttttaattt taaattaaca accagtaact tatatttgtt
    43261 ttaattttcc attattaata taaattataa gtataaaatg aataaaattc aatatttttt
    43321 gcaaaataca agagaataca aattaatacc tcgggaattt ttaagacaaa taccaatatt
    43381 atgcaattta gacttcgctt tctttcaaat tagtatcatt ttctttattt ttacatagga
    43441 tgtactttaa tttagctatc aaaacattgc tatataggtt aaaagttatt agaattgcag
    43501 gaattataaa gtaaactcta gcacctataa aaccaaaaac tactgtaata agtattaatc
    43561 ttttatttaa agtaaaaaaa ggtatattaa aaatactttt gtcggatgtt tctggagtat
    43621 aagaatatat aactccaaaa atcaaagtaa gcatacaaag tggaagtagt gtataacttg
    43681 aaattattcc caaaaatcct atactttcaa aatatttgct agcactattt gtataaacaa
    43741 acatgtatcc atttaaatat gcgcatatac atgatataat gccaaaagtt ccccctaagg
    43801 attgagtgta ccaattaaaa aatttagatt ccatatacct cacctcctaa aactgtatat
    43861 ataatgatat gcatttaaat agtaaaatat atctttatat gtttctgaat aaaattttgt
    43921 taatttcatt aatttatgtt taagaaattt gaagtatagt gtagtatata ttaatgtaga
    43981 tgaagtttta tagtacttat ttcatagtgc ttaatcaagt tatcttatta tggattcaaa
    44041 agttgtttgt agggttttat attttgttga gctgaaaaat ttattataaa tgaagggatg
    44101 ttttcgcttt ggtagataca ttagaatttg gtcttaaaat tttatttttt atattatcaa
    44161 taatttggat gggtaaaata atgattttaa gaactgataa gcaaatagta atcaatcctt
    44221 tgcttattgg tatatctgca atccttgtga tgttgcatac ctcacagagt aacattgaat
    44281 tttttggatt agatgtccaa tatataagaa tagttttgta tataatatat tcactgataa
    44341 ttttaatagg aatatgggct actaacagaa gaaatggaat tttttagata atctatttct
    44401 ataaaattta aaggttgcta gtaacaaatc actaatatta gcgttctgtt actaacaacc
    44461 tttattttga ttatacactt aaattgaaaa tagaatgatt gaataagttg acagattatt
    44521 ttacattgac agtaattaga acttcttgag atgtatttaa atcatttttg tcgcttagta
    44581 taacttttac cactgcttta cctgttttat tacctttaat tatcatatct tcacatgaaa
    44641 gtacactctt atcacttaca gatacaataa aatttaaatc ttttggaagg ttatcagtaa
    44701 cttcccagta tttataataa ctatcaattt tcttcgtaat tatttttctc aaatcaatac
    44761 tttcaccttt tgctatatca acattatgat atttagagtc cagtttatac tgattatctt
    44821 ttgtatcaat aaaatttaaa tcgcaattta catccacacc attatgagaa agagaattta
    44881 ctacatcgtc atcaatcaaa taattattgg caagatttat tgaatccata tcttttagac
    44941 ttaaagcttc cttaggaacc tcttttatat tattattcca aaaaataaaa ttgtctacat
    45001 tttcaagata tgatatacct tttaaatttg aaatactctc accagttgca taaaattctc
    45061 catctaaagc ctttatattg cttatagtca tctcatctgg atttatatat ctttttacaa
    45121 ctgctcttaa atttgcatca ggaaaaatat ctttaagttg attttcgctc aaaaccttat
    45181 catttgaatt tattggactt aaagctgctg cagaaataat aaatggtatt aaattagcta
    45241 aattcatagt accctcccac ataaattttt tattataata atttaatttc tatgagaggg
    45301 ttctgtttcc ttgttatata tacctacttt cgtacacttt attaatataa attaaaataa
    45361 atttctacta ttaaacttat aaacatatta ctagttacgt tttttagctt cacatctaaa
    45421 tattcgcata ccttgtgaca taaatttgtc ttcatactct gttgtaacat tattttcata
    45481 ctcactattt cctaaatcaa gagaaatatt ctttaatagc caattatttg cagcaatttc
    45541 atttaaacta aactcgaata atttttcatt atctgtttta aagtgaattt cgccatcatc
    45601 ttccaaaacc ctattgtaca tttctaaaaa tccagaatga gtgagtcttc ttttactcca
    45661 tctattttta ggccatgggt cacagaaatt tatataaatt ctcgataatt ctttagcttc
    45721 aaagtaatcc aaaatattgc ttacatctcc ccataaaaat agtatattat tcaaattaga
    45781 agcatctgct ttttcaacag cttttaaaag aacttcttcc ttaagttcca tggcaatata
    45841 atttatgtca gggttctgct tagctaaagt tgttataaac ttaccttttc cagtcccaaa
    45901 ttcaacatgt attggattat catttctaaa ctttaaattc cacttgcctt ttaatttgtc
    45961 tatatcgtct cttaaaacat attttgtata acttaaaagc ttttcatctg cacctttttt
    46021 tcgtcttctt ctcacaataa ttctccttac atataaaaaa ttagtaaaat acatttttat
    46081 tatacattat ctcaccaaaa aataaaaaga actctcttaa aatagaaatt tatttctata
    46141 aagagagttc taaacttact aaaaacttaa tcttagtggc accctgaaca accagagcat
    46201 cctcctccac cttgatcttt catattttca ggaataactc taaatccaaa tcctgtatct
    46261 tctattatta tatctccata ctgactatat tcatcagagc tcattacaaa ttgtaattct
    46321 ccaacttcat aagttaagtc atcttctttt ttctcatcta aagctaatcc aaaagaagga
    46381 cctccacaac caacacctgc aaagtatact cttatattat taggtttatc ttgattgtct
    46441 tttaagatac tttttaaagt atcaatagct gtttctggta aagtaatttt catcaaatca
    46501 ttccctttca aatattttat taaaacaata tctattatat acccatacaa ggtacataat
    46561 caattagttt ttgcatattt tactaaaact tctacctaat attacctaag gctttaaaat
    46621 attttatata atattttatt accttaaata aataccctat cataaactta gtaaacaaat
    46681 aaaattatta ttctaaaaaa tataataatt ttatttgttg ttttaatatt ataacacatt
    46741 tgataatgtc caattcatat atgcaaaatt tatatacttt aaaatatcta agaaattatt
    46801 caataaaaaa atactatttt ttaaaaatta tcattattga taaagctcta ctatttatat
    46861 tttttagtgt attcatgtat aataagtaaa agcacaacgg tatatactgt tgtgcttttt
    46921 tgtaattaat aaacaatatt ttggtctata acaatgaaaa atggctactt tccataattg
    46981 atttcatctg acataagcaa aaagggtgtc cagctgggtc aatcataact ctccagtcat
    47041 cagtaaattg ctcctctgcg attgtagctc cacaatgaat tgcatattga actgcttctt
    47101 ctaaatcctt aacagcgaaa tccatatgag ccatttgctg ttgagattca ggtttttctg
    47161 gttctattat gccccaagcc tttgtttttt gcaatataaa gaaaaaatta tatattttaa
    47221 tattttatac ttgttgaaat tgtgtaataa attcaactgg atacatagtg cgttttgaaa
    47281 tttcttctaa agctaaacct tgttttaaaa gcctctttat gacgctttcc atactttctg
    47341 aaatttctat aatattttta tcaaaatcat aaaacctaaa agttctttga ccccatgggt
    47401 attcttttat ataatgcaaa aattcaatat ttcctattct atttatctta ctttcccatt
    47461 gtttgatgtc attaacctca aaatacaact gaaagttatt tgattgttga tatattggta
    47521 aatcatatcc aattatagct ttataattac tttgtaatcc aaatccattt tcaaatgata
    47581 catgttctcc taaatctaat gtgatttttt gctccataac atcttcaaaa aacttttttg
    47641 atttatttat gtctttgaca attagcaata ctcctccaaa tttcatctta tcactatcct
    47701 ttctttgtta taagtattat aacttaaaat tttgcaattt cactgtaaaa atcagacata
    47761 ttagctcggt atttttgagg agttattcca cagacaattt taaaatcttt aataaaatgt
    47821 ggtatatcat agaatcctaa ttcattacat atagacatcc atgaagtttt attattgttt
    47881 agaagtttta tagatttatt aatacgtacc aaacgagaaa atgacttcat actcaaccct
    47941 agatactgat taaagagtct gtttaaatgc ctagaactat aaaatacttt tttagaaatt
    48001 tcttgtgaag atatatttcc agagttttga ataatcaact gaattgccaa aataaactca
    48061 tatgagtatt caattttaat attagaaatc aataattctt ccaactttaa aatcaattta
    48121 tctatagata aagattcatt aaatattttt ttaatttcta aatctaatga agtattaatt
    48181 atagaaaatg gaacaacttt atcaataagt tcactttgct gtatacctat aagcgggaaa
    48241 aaaccagcag gttgaaattc tataattagt ataacatcac atctattagc aatatttcct
    48301 actgtttttg gtttagtagt tggaccaaat aatagactat gtaaccctgt ggcatcataa
    48361 aaaaacacca aagttacact tccatgagga ataatcgtgt aattatcaga aattattgtt
    48421 tgatttggaa acgatatagt aaaattcgat atccaatttc ttaattgtat acaaggcaag
    48481 agataaacaa aattgtcttc acaaactata agtgacctat ttttatttat aaaatgaata
    48541 ctttcttttt ttaacatata ttatatcctg tcctatcgtg aatatttatt aaagtaagaa
    48601 gaatccatat tatctctata tatcattaac tgcttttaat aatagagata gtatgaatac
    48661 tcattagata tttaataaac aaataaaatt aaaataatca ataaaaaata tagtactttt
    48721 atctgttatt ttaatattat agcacattta tagtatttaa cttatatcca ctttacatat
    48781 gtctaattta tataattaaa aatgcttatc tcaaatacaa taattagtcc ttatacaatt
    48841 aaaccatctg aaactgtaat agtacgacta ctacttttgg ctgcttctgg tgagtgagtt
    48901 accataatta tagtttgtcc attgtctctg tttattttat tcagtaaatc tattatttct
    48961 atccctgttt tactatctaa atttccagta ggctcatcag caaatagaat ctctggtttt
    49021 ccaattaaag ctcgagctat agcaacacgt tgttgctgac caccagataa ctctcgtggt
    49081 gtatgtttac gtctatcagt taaaccaact atatctaaga tttcatctaa ttgattttta
    49141 taatctttta aatttttacc atctaataac aaaggaagca ttatattttc ctccacattt
    49201 aaatttggta ttaagttata aaattgaaat acgaatccta tatttctacg acgtattatg
    49261 ctcattttct catcattaaa atgtgatata tcagctccat tcatatacac ttttccgctc
    49321 gttggagtat ctaaaccacc taaaatatat aaaagagtac ttttaccaga accagattga
    49381 cccatgatag aaacaaattc acctttcatt acttgtaaag atacctcttt taacactcga
    49441 gttgttgtat ttccaatttt atattctttg ataatatttt ttgcttctac agctaaacta
    49501 ttatgtgtaa ttttcatatt aacctccata attattcaaa cttaatttct tctatcagtt
    49561 tcattttctt cccttttata ataggcacta tcgaacctat taaagttact ataattccca
    49621 ataacccaac aataataaat gttttaaaat ctaaatctgg tttcattgaa atttttggtc
    49681 ctgcaactat aaagatagtt tgaatctcaa gtatagatat cacaatacca ataacagctc
    49741 caagtaaacc tgaagtaacc ccttcaatca atgttacttt tatattttgt ttattactta
    49801 gtcctataga tttatacata gctatagaac gtcttttttg aatataatta atcagtagat
    49861 tattaataat acctactgta gcaagaagaa aaatgaaata ggtcatctta ttcataggag
    49921 acaaaaaact acttatagta tttaaagaat cattattaaa ttcttcaact gtacgactcc
    49981 aattatatgt atctccaaat aaatatctta tctgaatcat aacagcatct ggattgactg
    50041 ctgtatatac taaaaaacca taattagttt tatcaaaatc attaactgca taatgtgatg
    50101 gtataacagc ttctacatca tttgcacggg atttaaaact acctactatt ttataagaaa
    50161 aatcatactt atcattagat agagttattg tatctcctat agataagcct acttttttta
    50221 gagtatcttc attcaaaata acagaacgtt tatcattaaa agcttctatt acttgttttt
    50281 ttatctcaaa atttgtataa ttgattccaa acatagagtt atatagtttt atattatctg
    50341 taccctctag tcttgataat gttacaccat taccagaaat ctcattattc ataacataaa
    50401 gaggtaatat ttttttaatt ccttccatat gtctaacatc ttcaataaac tcttcattca
    50461 tatttccatc tgcaaaacct tgtaattctg cgtcacgaaa cacatctgtt atataagttt
    50521 tgacaaagtt accaacaaca cttattgcaa taactgcaga aatacttata aatagtaaag
    50581 tgatattctg tattatattt ttgttatttt tcatatttct agcagctaat ttaccctcat
    50641 tccctaaaat atttttataa acaaactcaa aaactataga catgatatca gtaataagag
    50701 gaatcaacac aatagtagct acaattaatc ctagtaatga aaatccacca gctagataca
    50761 atgtattttc aggggatatt cttggaagta aaatagataa aataaacatt atacttccta
    50821 taaaaagtat agaacgattt gaaacattct tttcttctac tgttcctagt acaatatttt
    50881 ttatcggcaa atggctagct tttttaacag gtatatatgc actaaatgaa gaaacgatta
    50941 ttgctactat aacagatata atcactccaa tgggtgatat tactactgga attgatattc
    51001 cttgttcgag agaatttcct aacccatgaa gcattaaatt taaaacaact acaccaatag
    51061 gaatagcaat taatcctcct atacttccgt ataatatact ttcaagcatc aatatacgag
    51121 ttacagtttt ttcattggca ccaatacttc taaatgttcc aataaaagga agacgttcta
    51181 atgtaataac cttataactg ctgtatatta taaatatact aagggttaat gcaaaaaaac
    51241 ttattaaaaa gaaaggcatt gtcttttgtc tagcatctga aattatctta gtttcattta
    51301 tagtatttga taccatatat ttttcagtag aaagttcttc ggataattta tttactagat
    51361 tttctgtaat ttcttcttct gactctataa gaactcttgt atatccactg cctttattta
    51421 taatttttga tagagtctct ttgggtagca gtgcatttac acctcttgtg ttcctcaaaa
    51481 atactgtatc ataagatgca atatcactaa cttgaaaagt ataagacttt ccataaatct
    51541 gcaaagtaat agaatcacct ttttttattt tatattttga tgtaaagcga tttggaagaa
    51601 taattttatc accagaaaaa tcagtaatac tatcgccatt ttctaatcgt ggcttgttga
    51661 ttttatttag ttgacttaag tctgctgata taagactaaa ttcttcatag tatccccctt
    51721 tattataaat agcagagctt tccaatacac caacctttga ttttatagta tttaaatcag
    51781 gtatgtcttc taaattggtt aatatatctg gatttttact ttggacagat atagtcgctg
    51841 taccatacat accttttgcc atttttcttt gtgcactttc ataagataat ccaattgaga
    51901 atgaaacaaa aagtaaaact gttgataaaa ctatggacaa taacataact gctgttctaa
    51961 tttttcgttc tttaatattt gtgaaaatat actttaatat aattttcaaa cttacacctt
    52021 cttcccttat ctaagatatt tcaatctaat atttttatac tttaatctaa attaaatctc
    52081 taatagactc ctccatactt ttatcattct atttataata tttttaatca aatcacccct
    52141 taaataaaaa agattgataa actactatat aaatataata atctatcaac cttaatatat
    52201 tttttattta accttaatta accttaatta aataggaaag gtgatataaa atgagctacc
    52261 taatccaggt atactttcaa cagatatatt ccctccatga acttcaataa tttgcttcgt
    52321 tattgctagt cctaaaccag ttccttctat tttttgtttt gtattgcttc ctctataata
    52381 acgattaaac aaatttgatg cttcttctct tgacatccct tttccattat cagatataat
    52441 gatttcaatt ctttcattta atgttacatg tacacaaact ttagtatttt tatctccata
    52501 tgtaaaagca ttgacaataa gattactaaa agctcgtttt aatagtgtac aatcaaaatc
    52561 aaagttaata ttatctatat tactcttaaa ttcaactata tttgattcat attctggata
    52621 atttaaaata tcaatggata attctttcaa gaatcttact aaatcataat tatttttatt
    52681 taaagggatt attccatttt ttaattgata ggttaatttt aaatcgttta taagtgtatt
    52741 tgtatattct atgttcttta acatgattga agcatattta tatacttttt caggtgaata
    52801 attagtacta ctatctgtaa gaagctctgc ataccctttt attggtgaaa gtggagtttt
    52861 taaatcatga gttatatttg aaatccactc ttctctcata atatcagttt tattttgtat
    52921 ctcatcactt ttatgaattt cttcatttaa aatatttaaa ctattatata tatcagcaaa
    52981 aacaccttta atattaactg gaagatagct tcgttttgaa atatcactaa cagcagatgt
    53041 aatatttgat atgcactttg ttacccagta accataagca attccagaaa ccaaaattat
    53101 taaaaatata atccctatga ttgaaaatac aattgactta ccacctataa atttacctcc
    53161 atcaaaaaac atattcactt tagatatatt taatggaaaa tatataatat aaatatagtc
    53221 atttttatta tttttaattg tattaaagta tacagttcca ttacttgaat tattttggtt
    53281 agctaatgct aataattcag aattagaata ataatcttta tgctcttttg gttctaaaaa
    53341 cccataaact ctatttccac tagaatctaa aatttgcaac cacaattgat tttctcgaag
    53401 tttttctaat ccagactgtt ttacttgtgg cttattatct ataaatacga tttgttcatt
    53461 aaagttttct gtaaattttt tcggccagtc actacgaata aattccccat ttggtttctg
    53521 aatagtaata agtgataaga aaatacctat tactgtcagg attaagcaaa taaaaatcat
    53581 gaaaaaaata atgtatgaat gaaatactgt tttataacta ggtttatgca tttaatcaac
    53641 tcttttctta aacttttatt ttagtttgat tgttgcttat ataaaataga caataattat
    53701 tgatatgtaa aaatttattt aaaaatacaa ctatctacat aaattatatt tatataatta
    53761 catgttatca agctgtctgt tgtatttaat aaatcatttt gataacatat aaaagtaaga
    53821 taaatttttc cattaaatac cttataatta tacacaaaat ctctatatac gttaaacaat
    53881 atagagaaaa ttttcataga accatcttta taggggatac tttataaaag aataaaaaaa
    53941 ttataatata taaaaaactt cataggagtg taacaacatc agtaaagata tgaaaacact
    54001 atataaaaat tcaaaaatat taagaataat gaaatacttg aaattgctta tatcaagaaa
    54061 ttttatataa tataaactgg tcaaatatgt tataatatta aattgtgaca agttcatgga
    54121 ggtgtttata tgaaaaaaca aaagtcgcca attttacttg aaatgcttgg actatttttt
    54181 ggttgtatat caatgagtat tggtataaat atgtttttaa aaccacatac aattgctcct
    54241 ggaggactta gtggtctatc attagtacta aacaaggtta caggacttcc agtatcagct
    54301 atcatgttaa ttataggtgt cccattagta atacttgctt ttagaattat gggtacaaaa
    54361 aattcattaa aaactttatt tggaacagtt gtattttcag ctatagttca attaacagac
    54421 ccattatcaa aactaagatt tactaatgac ttattattgt cttctattgc aggaggaatc
    54481 ctagttggta taggtttagg aataatgttt aaatcagatg cttctactgg aggaacagac
    54541 ttaattgcac tcatacttag taagaaattc ccaggaataa aagctacaaa attcatgtca
    54601 tgcctagatg gaatggttgt tatatcttct ggtatagtaa atcgtagttt agaaactgct
    54661 ctttactctg gtatagcact ttgtgtatta ataaaaatag cagatatgat aatggaagga
    54721 tttgaccatt caaaagcatt ttttattatc tctgatgagc ctgaaagttt aagacaagct
    54781 ataactgaag aacttgatag aggtcttact attcttgatg gtaaaggtgg atacactaga
    54841 gaaaataaag aagttctatt agtcgtagtt tctaaaaaac aagaacttta tctaaagaga
    54901 ttagttaaaa gaactgaccc tactgcattt gttattgtta cagatgtaca tgaggttctt
    54961 ggagaaggat ttaaaaattt agagaactaa taaaaattaa tattttaagt atatatacta
    55021 ttttaattaa aatacgattt attcaaaaag agtgtctcat aaacttttta gttcatgaga
    55081 cactcttttt tgtataaaat caaatgcatt ttcagtattt taacaataaa aacaggatta
    55141 tctatatttt gaggcaacca ctttattgaa attttattta gaaaacaatc attactaaat
    55201 aaccagcata gatattaaat gattatatct attgtttttt caattcatat tgataacaag
    55261 gaacattttt tacagtattt ccagtatgaa tttttttgat atactttcct gtacatttaa
    55321 atcctaataa atctaatgat tttgtagaat tttggttttc ttcataggtt attgcaatta
    55381 ttttatttaa gtttagttcc ctaaatccat actgtattac tctttttgtt atctcagtag
    55441 caaaatcatg tccccaatag cttggattta tacatatacc tatttctgct tctaatgctt
    55501 taggatttat attattaaac cccatattcc caataacttt attgtctctt ttatatacta
    55561 tagcaaagtg gccaattttc ccttttttat atggatttag aaaaaatgat tttataaact
    55621 ttcttgtatc ttctaaagat ttatgctcac taaatggtaa atgttttact actattttat
    55681 ttttataaca gtcaaaaaaa tcttcaacat catctaatga tgcaggtctt agtatacaac
    55741 ttctagtttc taaggttttc atttgaggat attcagaatc agacatttct aatccccctt
    55801 tatacattaa tctaaatata ctgttcatat ttaaaatacg atattaatta tataaatgtt
    55861 ctcaaattaa ccttattttt atttttaata aaaactaatt actatatgaa tctttcaaat
    55921 ttacgaattt atctctattt ttatattaaa ttacttgtga aatatgtatt ctaaattata
    55981 tattattaga tatcatgctt aaaaattctt tggttgctaa ggataaagat atatctttta
    56041 aatggcaata acctatattt ctcttaggta ttggctcttt tatatctaat ttaaacaatt
    56101 tctcattttc caaataatct atgctaaatt cttctataac acaagacact ccaagattta
    56161 tatacgcaaa ttctaaaagt aattcatgag aacccaattc tatatctggg tttagtttta
    56221 taccttttga taaaaaatat tcatttacat aaagtcttga atttgcttta ttttctagca
    56281 ttattaaagg caatgtgttt aattcttcca atgatatttt cctacctttg tattctatgt
    56341 aatcatttgc acatacaaat atatcatgta tttcaataca ctcaacaata tttagtgtat
    56401 catcttctat tggcatgttt ataattgcta tatctatatt cccatctttg agtaaagata
    56461 taagttctct actcgttcta tttattgtag atacatgtat atgtggatac ttcttatgaa
    56521 aaatttctaa atattttaac aagaaaaaac gtgcagctgt atctcctact cctattttca
    56581 gagaaccgta ttctaatttt ttaaatttat ttattctatc ttctcctgat gatattaact
    56641 ttaatgcagt agtgacatgt tcacttagaa ttttcccctc tggagttaat tttactcctt
    56701 tattgtttct ataaaataat aaagtatcta attgttcttc taattgcttt attgactggc
    56761 ttacagctgg ctgtgacata aacaattcct tagcagcaag agaaaaactc ttattattta
    56821 caactgcatt aaaaacctta taaagttcaa gttttatatt catatataat tactccttat
    56881 gtcaaat
//
LOCUS       DAYAKB010000020        54790 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.020, whole genome shotgun sequence.
ACCESSION   DAYAKB010000020 DAYAKB010000000
VERSION     DAYAKB010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54790
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.020"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            257..1021
                     /locus_tag="ACGI3L_001437"
     CDS             257..1021
                     /locus_tag="ACGI3L_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFG9197151.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(1302..2417)
                     /locus_tag="ACGI3L_001438"
     CDS             complement(1302..2417)
                     /locus_tag="ACGI3L_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HFG9197152.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLIFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(2458..3984)
                     /gene="glpK"
                     /locus_tag="ACGI3L_001439"
     CDS             complement(2458..3984)
                     /gene="glpK"
                     /locus_tag="ACGI3L_001439"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFG9197153.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4277..5374
                     /locus_tag="ACGI3L_001440"
     CDS             4277..5374
                     /locus_tag="ACGI3L_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9197154.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRY
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(5865..6377)
                     /locus_tag="ACGI3L_001441"
     CDS             complement(5865..6377)
                     /locus_tag="ACGI3L_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197155.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            6930..7811
                     /locus_tag="ACGI3L_001442"
     CDS             6930..7811
                     /locus_tag="ACGI3L_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HFG9197156.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKSVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(8124..8903)
                     /gene="hisJ"
                     /locus_tag="ACGI3L_001443"
     CDS             complement(8124..8903)
                     /gene="hisJ"
                     /locus_tag="ACGI3L_001443"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HFG9197157.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(9449..9799)
                     /locus_tag="ACGI3L_001444"
     CDS             complement(9449..9799)
                     /locus_tag="ACGI3L_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HFG9197158.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(9815..10231)
                     /locus_tag="ACGI3L_001445"
     CDS             complement(9815..10231)
                     /locus_tag="ACGI3L_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HFG9197159.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(10250..10441)
                     /locus_tag="ACGI3L_001446"
     CDS             complement(10250..10441)
                     /locus_tag="ACGI3L_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HFG9197160.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(10592..11407)
                     /locus_tag="ACGI3L_001447"
     CDS             complement(10592..11407)
                     /locus_tag="ACGI3L_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HFG9197161.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(11454..12392)
                     /locus_tag="ACGI3L_001448"
     CDS             complement(11454..12392)
                     /locus_tag="ACGI3L_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9197162.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(12389..13261)
                     /locus_tag="ACGI3L_001449"
     CDS             complement(12389..13261)
                     /locus_tag="ACGI3L_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9197163.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(13286..15214)
                     /gene="acsV"
                     /locus_tag="ACGI3L_001450"
     CDS             complement(13286..15214)
                     /gene="acsV"
                     /locus_tag="ACGI3L_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="corrinoid activation/regeneration protein AcsV"
                     /protein_id="HFG9197164.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(15326..15703)
                     /gene="gcvH"
                     /locus_tag="ACGI3L_001451"
     CDS             complement(15326..15703)
                     /gene="gcvH"
                     /locus_tag="ACGI3L_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HFG9197165.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(15790..17916)
                     /gene="acsB"
                     /locus_tag="ACGI3L_001452"
     CDS             complement(15790..17916)
                     /gene="acsB"
                     /locus_tag="ACGI3L_001452"
                     /EC_number="2.3.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit alpha/beta"
                     /protein_id="HFG9197166.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(17973..18779)
                     /gene="acsE"
                     /locus_tag="ACGI3L_001453"
     CDS             complement(17973..18779)
                     /gene="acsE"
                     /locus_tag="ACGI3L_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase/acetyl-CoA
                     synthase methytransferase subunit"
                     /protein_id="HFG9197167.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(18829..20196)
                     /gene="acsC"
                     /locus_tag="ACGI3L_001454"
     CDS             complement(18829..20196)
                     /gene="acsC"
                     /locus_tag="ACGI3L_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HFG9197168.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(20227..21171)
                     /gene="acsD"
                     /locus_tag="ACGI3L_001455"
     CDS             complement(20227..21171)
                     /gene="acsD"
                     /locus_tag="ACGI3L_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HFG9197169.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(21191..21961)
                     /locus_tag="ACGI3L_001456"
     CDS             complement(21191..21961)
                     /locus_tag="ACGI3L_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase accessory protein
                     CooC"
                     /protein_id="HFG9197170.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(22017..23402)
                     /gene="lpdA"
                     /locus_tag="ACGI3L_001457"
     CDS             complement(22017..23402)
                     /gene="lpdA"
                     /locus_tag="ACGI3L_001457"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFG9197171.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTIKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(23446..24327)
                     /locus_tag="ACGI3L_001458"
     CDS             complement(23446..24327)
                     /locus_tag="ACGI3L_001458"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HFG9197172.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(24362..25036)
                     /locus_tag="ACGI3L_001459"
     CDS             complement(24362..25036)
                     /locus_tag="ACGI3L_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HFG9197173.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(25073..25945)
                     /locus_tag="ACGI3L_001460"
     CDS             complement(25073..25945)
                     /locus_tag="ACGI3L_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HFG9197174.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(26037..26669)
                     /locus_tag="ACGI3L_001461"
     CDS             complement(26037..26669)
                     /locus_tag="ACGI3L_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HFG9197175.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(26774..28450)
                     /locus_tag="ACGI3L_001462"
     CDS             complement(26774..28450)
                     /locus_tag="ACGI3L_001462"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFG9197176.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(28699..29478)
                     /locus_tag="ACGI3L_001463"
     CDS             complement(28699..29478)
                     /locus_tag="ACGI3L_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9197177.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(29788..31707)
                     /gene="cooS"
                     /locus_tag="ACGI3L_001464"
     CDS             complement(29788..31707)
                     /gene="cooS"
                     /locus_tag="ACGI3L_001464"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HFG9197178.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(32314..33225)
                     /locus_tag="ACGI3L_001465"
     CDS             complement(32314..33225)
                     /locus_tag="ACGI3L_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HFG9197179.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(33341..33919)
                     /locus_tag="ACGI3L_001466"
     CDS             complement(33341..33919)
                     /locus_tag="ACGI3L_001466"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HFG9197180.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            34145..35068
                     /locus_tag="ACGI3L_001467"
     CDS             34145..35068
                     /locus_tag="ACGI3L_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9197181.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(35240..36382)
                     /locus_tag="ACGI3L_001468"
     CDS             complement(35240..36382)
                     /locus_tag="ACGI3L_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9197182.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELRINK"
     gene            complement(36400..38154)
                     /locus_tag="ACGI3L_001469"
     CDS             complement(36400..38154)
                     /locus_tag="ACGI3L_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HFG9197183.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            38290..38496
                     /locus_tag="ACGI3L_001470"
     CDS             38290..38496
                     /locus_tag="ACGI3L_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197184.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(38501..39424)
                     /locus_tag="ACGI3L_001471"
     CDS             complement(38501..39424)
                     /locus_tag="ACGI3L_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197185.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(39678..41378)
                     /gene="argS"
                     /locus_tag="ACGI3L_001472"
     CDS             complement(39678..41378)
                     /gene="argS"
                     /locus_tag="ACGI3L_001472"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFG9197186.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(41840..42253)
                     /locus_tag="ACGI3L_001473"
     CDS             complement(41840..42253)
                     /locus_tag="ACGI3L_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFG9197187.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(42321..44699)
                     /locus_tag="ACGI3L_001474"
     CDS             complement(42321..44699)
                     /locus_tag="ACGI3L_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFG9197188.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            45018..46469
                     /locus_tag="ACGI3L_001475"
     CDS             45018..46469
                     /locus_tag="ACGI3L_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HFG9197189.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(46673..49186)
                     /locus_tag="ACGI3L_001476"
     CDS             complement(46673..49186)
                     /locus_tag="ACGI3L_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9197190.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(49409..50230)
                     /locus_tag="ACGI3L_001477"
     CDS             complement(49409..50230)
                     /locus_tag="ACGI3L_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9197191.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(50748..51224)
                     /locus_tag="ACGI3L_001478"
     CDS             complement(50748..51224)
                     /locus_tag="ACGI3L_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFG9197192.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(51258..51836)
                     /locus_tag="ACGI3L_001479"
     CDS             complement(51258..51836)
                     /locus_tag="ACGI3L_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFG9197193.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(51940..54522)
                     /locus_tag="ACGI3L_001480"
     CDS             complement(51940..54522)
                     /locus_tag="ACGI3L_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFG9197194.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSSISMDLYTSSSLGIPKELMGSNTNNIYTLSNTSKIDTLNKNHSNTA
                     VTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNIDCYLNA
                     FNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVTEYCPMG
                     VVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLDNLYELE
                     EIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKRATDLYKKLDEIGTVAGHYY
                     KGVE"
BASE COUNT        16971 a        10313 c         6178 g        21328 t
ORIGIN      
        1 atctctatac taataaatta tataataaaa tcatatttta gtcaattgtt ttataaaatt
       61 tgagttattt tgaattatta aacatctatt tttacttttt tgcttaaatg taagttttaa
      121 atatggtaaa attatcttgc ataacactta taatattatt tgataaatat acatacatta
      181 acaaatatac ctaaactctg acttaattgt aagttatgcc aaaactaaaa taatactagt
      241 ccaaggagga tattttatgt taccacagga aagatatgag aagattttaa gtattctcaa
      301 atcagataat ataattaaaa taaatgacat agttcaaatg tttgatatat caatagaaac
      361 tgcacgaaga gatttagccc atatggagag tatcggtctt ttaaaaagag tttatggtgg
      421 tgctatacca gttatagcaa gtagcgtaga acttaactat gttaaaagaa aaaaaataaa
      481 ctcaaacgat aaaaaacaga ttgctattaa atgtagtgag tttataaata caaatgatac
      541 tatttttatg gatactggaa ctactgtact tgaagtttca aaaaatttga aagataaaaa
      601 gaatctaact gtaataacca actcaatttt agttgcaaac gaacttatga atactaatat
      661 aaaagtatat gtgcttgggg gctatcttag agaaactgaa ggttcttttt ctggtccgct
      721 tacactgtca gctattgaac aatttaatgt tgataaagct attttaggcg ctggaggtat
      781 cactcttgaa aatggaatct ctgactatca cttagaagaa gcacttgtta gaaaaaaaat
      841 gattgaaagg tctagaaaat ctatagtagt tgtcgaacct cctaagtttg gtataaattc
      901 atttgcatca gtagctccta tagaacatat agatactatt attacctctg ctagtataga
      961 ccataatata ataatagagt tttctcaaaa aggaatacct ttagtcatag ctgataatta
     1021 gcttatatga ttgattttta gttccttgat gtaataaatt aaaattaagg agccaaataa
     1081 ttatttattt agctccattt atgtctaaac tatactttat attttaatta tgtaactact
     1141 ttcagttagc ttatcatttt tagttatttg attgccattt tatttaattt ataagtttta
     1201 gttattcgat tattttttaa ttgtctgtct ttttaattta tttttagtta tttaaactcc
     1261 tactttaaaa taatttaaat ttgacttaag tattgtttat tctacactgc atctttcttc
     1321 attttaatac tttgttcttc ttccaaggtt aaatcttttg tcataagtat agcaagtgca
     1381 attgccaata ctcctccaac caattttcca attacaacag gtgtaatcat ctctggaact
     1441 actcctgctg taaatcctaa atggtccccc aaagctgctg tagcacaaac cagccaagca
     1501 gtatttacta ctttcccctt tggactcata tctttcatca ttttatatac tggaatacta
     1561 ttggctaaag taaaaactaa tcctgctgca ctagtggcat ccatacctaa ttttccaccc
     1621 actattgtaa gtggtttatt aagaacttta actaataaat gtaatattgg aaaagtacct
     1681 aataacacga ttgcaatact tccaattact tgaatacctt ctcttatagg tgtcatgcct
     1741 tttataagta ctatacctgt tatttcttga aatgctgctg ctcccaaacc tatcgttatc
     1801 aatatagata taaattttcc aaaaattaat gacccattta tcataagagt agaattaaat
     1861 tttaaaccta ctgccaatat tactgccaat attatcactg gtatcatatt tataattacc
     1921 attgataagt taaatcctgc tattaatcct cctataatac ctccaaaggg tattgttatc
     1981 aagcctatca gtaacccttt tgcaaagaat ggtctgtctt catattctat aagacctagt
     2041 cctactggaa ttgaaaatac taatgtacat ccaagcatgg atgacacaac caatcctgca
     2101 agcattcctg cctctttatt gtgtgcaagt tccatagcca atggataccc tcccatatca
     2161 ttcgctaaaa tagttgcaaa catagatggg tcagctccac agagattgaa gattggtatt
     2221 attataggac ctagtacatc tgaaattact ggagctaaac aaactatacc aaccattcct
     2281 aaagccaatg gacccattga attaaaccct tcttcaaact gctcgccaag tccaaattta
     2341 tttccaatta ttctatctaa cgctcctaaa agcactccca cagccattat gtataatata
     2401 attttatcaa agggcatttt taattcctcc tatacatgta aaatactcta ttgtaactta
     2461 attagcacac acctttttgg tatcgttttc ccaattcata gctcttttta ctgcttggtt
     2521 ccatccaagt aatatttctt ctcttttttg agtagtcata tttggaatat attttttgct
     2581 tattgtaaat tcacttctaa tttcatcaat actgttccag acaccacaag aaagacctgc
     2641 catatatcct actccaagta ctgtcgtctc aggattttct gcaatttcaa ttggtatacc
     2701 taatatgtcg gattgaaatt gcattgtaaa gttattttta gtaattccac catctactct
     2761 caacattttt atttttttcc ctgaggctaa gttcatagaa tcaacaacat ctttgacttg
     2821 aagtgcaaca gactcaagag tcgctcttac tatatgctct tttttagtac ttcctgttat
     2881 cccaaccatt gtacctctag catattggtc ccaataaggt gctgctatac ctgcaaatgc
     2941 tggtacaaaa tatacacctc cagtacttga tatggaattt gccatgtcat cagtttctga
     3001 ataatttttt ataactccaa tgccatctct aagccattgt attgcagcac ctgctatata
     3061 cactccacca tcataagcat atgtaacttt atctcctatt ttccaagcaa cagttgtcaa
     3121 aataccatta cctgctatat ttagttcctc acctatattc atatatagga aacatcctgt
     3181 accataagta tttttaacca ttcctggttc aaaacatcca ttgccaaata aagctgctgg
     3241 ttggtctacc attgaagcag taatttttat agaaacccca caaaatgcct ccttatctgt
     3301 agttccaaaa tcaccactcg taggcattat atctgctaaa atacttctag gtactcctat
     3361 aatgtcaagc aactctctat cccaatccat atctcttata ttaaaaagca ttgttcttgc
     3421 tgctgtagat acatcagtta aaaaagattt tcctcctgtc attttccata ttaaccaact
     3481 atctaatgtt cctgcaagta cttctccatt tttaattttt tcttttacac cttttacatt
     3541 atctattacc catttaattt ttgtacctga gaaatatggg tctataatta acccagtctt
     3601 atctattatc ttattttcta aacctggtat attctttaaa ttttccacat aatcataagt
     3661 tctcctgcac tgccacacaa tagcattgta aagtggttta cctgtatttt tatcccataa
     3721 cattactgtt tcaccttgat tatctatacc aattcctttt atatcacttt cattgattcc
     3781 attttcaaaa gcctgttgta atacattatt actcacagtt tttgtattat tccaaatttc
     3841 tatagggtca tgttcaacat atccagattg tggatatatt tgagtatgtt ccatataatc
     3901 gctaaaaaca aactctgatt tttcgtttat caatactgct cttgttcctg ttgttccttg
     3961 gtcaattgct aatacatatt tcactttaaa tgtcctcctt tattttcaga attaataaat
     4021 tcttttttat tttttgaata tataatctat tcaagttatt tatattttat atcatcatgt
     4081 ggatttatgc aatattcatt acaatatttt ttgttatttt taattatagt gattgaaaaa
     4141 gtatttttat tgaaatattg ttgcaatatt tattatttta ttctataatc tagttaaaat
     4201 aacacataat attttaatat ttacacataa tcagtcattc aaaaatttaa atttaacttt
     4261 ttaaggaggc tttacaatga aaaaaacata tctattcagt cctggaccag taatggttac
     4321 agataaagtc agaaattcac ttcttcacta tgatatatgc catagaggaa atgagtttat
     4381 ggatttattc aaagatacac aacaaaaaat caataaacta tataatgcaa cttctaatta
     4441 ctactcatta attgtatctg gctctggaac atctgtaaat gaatgtgtac tatcttctat
     4501 ctttgacaaa gaagatgcag ttctgctagt tagtaatggt gtttttggag aaaggctaga
     4561 agaaatatta tctacttata atgtaaaaac atataaacct aattttgaat gggcagaata
     4621 cccggaccta gacattttag aaaaatacat aattgaaaac tctgatataa aagtaattgc
     4681 tatggtgttc catgaaacta gttcaggaat gataaatcca gtccctgaac taggaaaact
     4741 tgctaagaag tataacaaaa tattttttgt agatgcaata agtgcctcag caggtgaata
     4801 tattgatgtg gaagagttta atatagatat aataacaggt gttggtggca aagctcttgg
     4861 agcatttcca ggttctgcat acctttgtgc taaagagagt attttacaaa atattaaaga
     4921 aaatcaatgt aagaatgtgt atcttaatct ttataaacac tataaagttg ctaaatcatc
     4981 ttctcaaaca ccaaatacac ctaatgttac tttaatattt gcccttaatg aagctttaac
     5041 tgagtttttg gaagatgaca gtaaaataga aagatacaaa gaatgttctg ctattttaag
     5101 gtatggtatg gaagaattgg gtctaacatt tttacttcca gataagtata tgtctaatac
     5161 agtaacatct gtatttctac ctaaagaaat caatgtaaat gagtttatat tagggctaga
     5221 aagggaaagt ggctatgttg tctatccagg aaaaggcaaa ttcctagatg ctaacatatt
     5281 ccaagtagca aatatgggag aaatatatcc agaagattgt tataaattct tagatatctt
     5341 aaaatcaaaa ttggagataa aaaaagttat ataacagttt gtttgtaaaa tcctacaata
     5401 tatcagtata aattaaatag actgattttt ttaaattttc ctataataaa ttatatttta
     5461 tatttttgta taagggtgaa ctataatatg taaagttcac ccctatttca aatctttttc
     5521 cttcaatata atctttttct tttaatttat tttatatttt tgacgcaatc gttttttatt
     5581 caatcatttt atattcttga tacaatcatt cttacactta attatttttt gtttttgaca
     5641 caatcgtttt ttgttgaatc attttatatt cttgatacaa tcattcttac acttaattat
     5701 tttttgtttt tgacacaatc gttttttatt cagtcattta atattttcaa cacaatcatt
     5761 cttacattct attattgttt gtttttgata caactgtttt tattcagtca tttaatattc
     5821 tcaacacaat taccttttca ttcaatcaaa gtaatcttta agcattattt ttcaagctca
     5881 tcaaagtaat tatatacgat aacctcacct gtctctttat ctgtagtctt tataatgccc
     5941 ttagctccat ttacctcttc ttttgtaaat tcatcatcta acacaacttt gaatttatct
     6001 tcctttccat aaccttgttg aaattcatct ctcaaaattg catttttttc tgcttttggc
     6061 ttcaactcaa attcaattcc agatttcatt tcatcaaaat aatttaatac tacaacctca
     6121 ttattcattt tattagttgt ctttataatc cctttagctc catttacttc ttcttttgta
     6181 aattcatcat ccaatgttat attaaatttg tcttcttttc catattcctc ttgaaaatcc
     6241 ctcttcattt cattgtattt agtttcaaac tctttactct tgtttaattc catagctgat
     6301 acatttgtca atgatgctcc aattgccatt actgttaatg ccattactat accactttta
     6361 aattttttta ctttcatatc ttacctccta aattaaatgt tctcaatgaa attatataaa
     6421 gaaaatccta agttttacag tttcattctt gtaactaaaa ttactattat gtaaccaaac
     6481 tttttgcttc aactattcct taaaagttgc ttttttgagg aatagttgaa gttaaataat
     6541 tagattttat ctatatttat agatttaaaa tcaaatttat ccatataaat aaatacttat
     6601 ttttgcaaaa taaaaatttt taattactcc aatccttctt atttacttaa aatcctatga
     6661 taagaaattt aaaagtcttt accttcttta acaataattt atttactttt aacatacaaa
     6721 atatagagag tatatcaaaa ctattttact gaatattcta aaaataagta ccccctatta
     6781 gtatatatat ttacatatta aaaaaaagtt ttaaataaag ttatattttt tacaacagtt
     6841 ttgtaattaa aaacatattg aaggtaaatt taaaggtact atatactata aatatgtcga
     6901 cacaataaat ttaaaaagga gaactaaata tgaaaaaaag attaataata atgatattgt
     6961 ctgttgtctt agtactatca agtatactta cgatatttgc atattcaaat attaaatata
     7021 ataataacaa attgatatat tctaatatga tagataaaaa aactcaaaat agtgtaaagg
     7081 aaatcctaaa agaaaataaa attaatgaaa aagacataga tacatttatt aaatcagtca
     7141 acaattataa taaattgcaa gttaaaatac ttcaaaataa tataaatata tctaaatctg
     7201 gatattcttc aatcaatgca aaacaagttc catataacct agaaaaattg caagataatt
     7261 gggtgaaaaa attccctgat tatatggatg taaattgtag aataactgct tttagacttt
     7321 ttaaagattt tataaattca aataagaaat ttactggaga ctctattgat ttgaatgtcg
     7381 acttggacac tataatgaat aataaagatg ctaaatttag caccaaagat gtagaaaaat
     7441 ttatcaactt cttttctgca ataccagcta aagatacaga tgatacaatc aaaattgcag
     7501 aacaaataaa aaatgaatgg aaaaaaagaa aaatatcttt taaaaataat aaaaatatat
     7561 ctattataaa tggatttctt cgttatccag aaactaaaaa tgtatttata ggtcatacag
     7621 gcatatgtat taaaactaaa aatggcattc tatttttaga aaaatacggt gttacatcac
     7681 cttatcaagt tactaaattt aaaaataaag aagatgtaaa aaattatatg tttaatagat
     7741 tgaagatgtc agaaggtgaa attgaattac ctgaccctat aataatggaa aacgataaac
     7801 ttatgaaata ataactttaa acgcaaaata gtatttataa ttactaagtc aatataatag
     7861 agaaggtcta tagatttgtg taaatacaag cttatctaca atcttatata agaatgttta
     7921 tataaataag atagattaat tctaagtcct attattctat tgaattttat tattatttta
     7981 tttagattct attgttattt tacttagaac ttattattat tttgtttaag ttctattact
     8041 attttcaatc atataaattt acaaaagact gtacataaat ttattttata caaacttatc
     8101 tacagtcttt tgtgtgaata tatctaaata atatcgtatt tatttatttc ctctgcacag
     8161 tgagaatcag aacctaaaac taatggaata tcgtattttt ttaccaagtc taataagtat
     8221 ccatctatat aaggctcttt gcagtactct tttctatttc cagaaacatt ataatcaagt
     8281 tcataacctt tttctttaat taactttatt aactcttcaa gaattttatt tcctttataa
     8341 tcgtatggaa atacctgatt aaactttcta actaaattta aatgacctat tctttttggt
     8401 ttatgtatac ctaaatctga atttacagct tttatcaatg tttcataata cttattataa
     8461 acagcttcaa tacttcctaa tttgtcgatt aaattttgaa actcctctac actgtaatct
     8521 acacaataat aatcatcatc aatcttaatt atatgtactg ataaaagaga atcctctaat
     8581 tcctttccat atttatttaa attctccttt atcccttctt cgtatccttc tataaaatcc
     8641 acttccgacc caacatttat cttgatttta ccctcatact tttctttcaa cttcttgaca
     8701 tcattaaaat actttggtaa atcttcaata ctcatacaac tatcattttc aggagcaggg
     8761 tctctaaatc catttgcata cggaaaatgt tctgtaaatg tcatttctgt tattccaaca
     8821 tccattgctc tttgtacata tttttcaaaa tcatccttac ttccatgagg acaataaggt
     8881 gaatgtatat gaccatcttt cataaataat tcactccttt tttaaagaaa aaatctaata
     8941 taaatgcata aatcttttaa cttcaaaata atatttttaa tcatgctaat ttttattata
     9001 tctaatatta gagtaatttt aaactgcctt ttaagtatct tatcattagt actattttca
     9061 acttaacatt aatattattt tttaacttaa cattaatact atctttaaat agtaatactc
     9121 aatatataat tacttaacat aaaataactc aaattgcttg atgaggcttt tgcagtattt
     9181 aaagaatata taattattta acattaaata atccaatctt gtaataaaat ttactcatta
     9241 aagtatatta cagaaaatac ctcaaaataa actttttagt tcatgatata ctcttttttg
     9301 catgaaatta gatatatttt tatcatttca acaatgaaag ggaggcttat atccatcttt
     9361 agacaacccc ttagataaaa tttttaataa ttaaacatca caaaatataa aaatcgctta
     9421 tatcaaacgt ataagcgatt aattatattt acatatgttt tttagcctct aacaacattt
     9481 tattagcttc ttccatatac tctatagcct tttcaatact ctttgctgtt tcttcttttc
     9541 caatagctct agccttttca acccactctc taaatccttc ttcatgagtt tcattgtgat
     9601 ttatccaatg tactaaaagt atttttaaag ttttttcatc cttagactct gatgattcct
     9661 catgactatg ttcgtggtcg tggtcgtgag catggtcatg tggatgttca tgacatatat
     9721 ctccatgagt atgttcgtgg cagtggtcat ggtcatgatg tccatgatga tatcttacaa
     9781 tctctttatc aaaaatcatt agttattccc cctgttattt tatattaaac tcttttttta
     9841 taaggtttac agaatctttt acaagtagtg ctaatggttt accttctaat ccaactaact
     9901 ccacattttc tggcataata ggtaaaagta tcttaagtgc ctcactgtct gcaatagctt
     9961 cacttatatt acaagtaact tctcccatca tagaattagg tattattaca gaaataggtg
    10021 caactattat atttgctttt ttagctgata ctactatagc attttcccct gtagctcctt
    10081 tattagcatg agctttcatc atagaactag ttgctataga attagtccct agtgcataaa
    10141 tttctacata tgtaggtaac tcttctctca aagaagaaac tatctgggct ccaatacctc
    10201 cacccattcc atctatcact gctattatca tatgaaattc ccctattaat taattttctt
    10261 gtattattat cttatggtcc atcaatctta tttctttaat tatcccatct attatctttt
    10321 gctctcctaa taaatccgtt aaataaatct ttccatcaca agggtctata ttaaccacat
    10381 tttccataac cttttctaac tcattattac ttttacaaat gaaagctgat gattcacaca
    10441 tataaatctc ctcctaatat gatttttatt aaaaatcaaa aaaagattcc cttaggtatt
    10501 tcaatacacc aaagaaacct tcatgatttc agtttttgta tattattata ccttaagtat
    10561 atcactttaa tttatgtaaa gtcaattaaa gttaacgctt tttattatac tcttcattct
    10621 tgtatttttc atatagttct ttaactaatt gcttctcata atcagtcaaa tcgccctcca
    10681 caaactcaac attaaattgt tcagctaatc cctttactat gtttttctgt agaatatcta
    10741 tgtctatttt tctgccaatt tcattttcta ttccacttgc ttttttagct gtaaatttca
    10801 tagctctttc tttcaattct ggtgtcttag tttttattaa tttaaacaat ttttctacat
    10861 caaaatccag tattattgaa ccatgttgta ataaaacacc atcttttcta ctttgagcac
    10921 ttccaattac cttcttatta ttaatagtaa cttcatatga tgcatgtgca ttaaaacatg
    10981 cagctgataa attttcccta cttattctct cgcctctatt taaattatct gtttctatac
    11041 cacttagatt caacccttta actagacctt cacttatata tctataagat aggttgatgc
    11101 tcttatcgat taaaggatta tcttctccta taattatact ataggttagc tcattatcat
    11161 gtaatacagc tcttccacct gtaattcttc tagtatagtc tatattcata catctacact
    11221 tatctaaatc tatctcatct tccaatttct gaaaatatcc tatactcaaa caagctggtt
    11281 cccatgtata aaatctaaga gttggcttat tatgtccttt cttatatgca gtaaatatag
    11341 cttcgtcaat tgccatattc attgctcctt catatgattt attatgtata actctccact
    11401 gattcatgat tattacgcct ccatttttag tataaatata tcctagaaat cctctataga
    11461 tttatttctc ttattgctaa atctatctca ctttgattta aaggtcttga atagttgtat
    11521 atagtacttc ctggtctttc attatagtat ggtctattac aatccttaca acctcttatt
    11581 tcaaaaggat agcctttgtt tatgtctttt aaaatatcat tgtcaagctt tatactattt
    11641 aagtatccat ttttaaactt aaaatactct tttggataac ctttatttat catataagac
    11701 attaactgta cccttctata actttctatg cttggttgat ttatcttttc cattttagtt
    11761 cctctaactg gagtaaatgc aaataaacta atcgttacat cattttcctt taaataagta
    11821 tataaattgt atatatcttc atgactttca cccataccaa ctattatatg tgtacttatt
    11881 ttattgggat atgattttga catttcagtt ataaatttta acttttcatc atagttattt
    11941 ccttttattt tttcatatag ttctttattt gctgcatcta ttgctattcc tattttatca
    12001 actcctgctg aaaaaaactt ctttatctgt tcatcatttt ctaattttgc agatagtgaa
    12061 attggcatgt ctatcttacc acttatatag tttataaagt ctaaaacaga gttatgtgct
    12121 tcttcacttg ccattgattg aatacatatt ctctttatat tttttccttt ataagctttt
    12181 aaagcatcta atatttcttc ttttgaaaac tctggccaaa ttactcttga taatttatct
    12241 tttctagtac tactttctat tgattgagaa caaaaactgc atttatttat gcatttttct
    12301 ccaatcatta tatatgctgt ggtaggaggt atatcgcttt ttttgtttaa tatcccaagt
    12361 tctattgctg tcccaactga tagtctaatc ataaaacgca acactcctta cactcattta
    12421 ttgtcatatt catttctata gccttattct ttgcagacct tgatggtaat actattctat
    12481 tgactccaca cattatagat aattggtcta gctcttttct atacactcct cttggtctca
    12541 tacaacctag attaatttca gtatctggta aattaattct agcttcacat aaaatatctg
    12601 ctaccccttc taactcagga ggttctacat tttcatactc agtccctttt gttggaataa
    12661 ggactataaa tgtaagctta ttaggaggat ttttttgtag gtattctata atttcatatt
    12721 caccctttat ttgtcctcct tttaaaccaa tacatatatg tggtgctact tctgtatgtt
    12781 cttgtattgt attatagact tcaatataat cttctttact ctttttcatc ttataaactt
    12841 ctcttattgt ctcatcatca aacactaaat caaaagaaac tatatctaaa tacttacaca
    12901 actctacaat gctatcttta tccataagac ctaaatgagc attcaatcta tatccttgct
    12961 cttttaagtt tttaatggta ttaatatgag tatttatagg gacatctccc tcataactac
    13021 aaccgccact caatagaaag ctagttatat tccttgattg tactttttcc tcatattctt
    13081 ctattggcac catattgttt aagtagtgac cgttgcaatg ggcacatttc aaactacatt
    13141 gattgcttgt agtactaaga gctagtgtct ggttaggata agcaaactct attttatttc
    13201 caaaattctt taatttaata tcaaatgcta ttttcatttt ttcagataga ttcttattca
    13261 tagtttattc cttcttaagt acattttact cttctagtaa tttctttgct gttgggaact
    13321 gctctatatt cgtatgtggt aagaaacatg cagaaataaa ttcatccata taacttggat
    13381 atacactaag ttcaacataa gttatttgat tacctatttc ttcaagttta ttttttgcat
    13441 ctttacttat aagcgctaag taagaaccaa caagtgaact attccctata taagtaaatt
    13501 tttctctatc aatatcagga agtaacccta taattattga gttttctatg tctaggttgt
    13561 ttcctatacc acctgctata taaaccctat ctaatatact aaaatccata cctaaactat
    13621 ctacaagagt gtatgcgcct gaatatatag ctcctttagc tctgatgaaa ttatctatat
    13681 caacttcatt gactactata tcattttcta aatcaaattc ttctttaaat gctaatacat
    13741 actctcctat ctcatgctca ttaaatctaa ctctcttatt atctaaatcc ctgtatattt
    13801 tacctcttct atctattaca cctttagtaa tcatttgaca gattaaatca attataccag
    13861 aaccacatat accaactggt gcacattcat caataatctt taatgttggc tctaaagtat
    13921 ctttatcaat aattactttc tctattgctc ctgctgatgc tctcattcca cagcttatcc
    13981 ctccaccttc aaaagcaggt cctgctgaac atgcacagct catcatataa tctttatttc
    14041 caaatacaat ctctccatta gttcctaaat ctataaataa aacattttct tcacttgacc
    14101 atatccctgc tgataataca cctgctgtta tatctcctcc tacataactt gcaacagatg
    14161 gagctaagta cacatatgca ctgtcattta caaaaagacc aacattttca cccataagtt
    14221 ttggagattt taaaaatggt ggtatgtaag gttcttgtct taagaagtct gtatacacac
    14281 ccaagaataa acttgtcata gttgtatttc cggcagccac taatgtaact acatcttcct
    14341 tatctattcc atttctttca tatattgttt ttaatagtgg atttatagtt tcctcaacta
    14401 tagctttatg aagtgtctct aatccatttt tcttagttga atatataatt ctatttataa
    14461 catctgctcc atattttatc tgtgcatttc cagaagatgc tttatctact acctcttttg
    14521 agtataggtc tactaaacaa acaactactg aagttgtacc aatatctatt gcaactccgt
    14581 ataaggaatt ttctttattt ccttgttcta tatttatgat tgtaagtttc ttttgttttt
    14641 gaacatatgt tattgtaacc ttaaaatcac tctttctaaa tacagttggc atttttctaa
    14701 gtatatccaa tctaaaatct atttcattat atcctaggtt atttctaaca tatctttcca
    14761 atctatctac atcacttata ttatcatcta aatttggttc ttccatttct atgtatttct
    14821 tttttatatt tgttttaaat tgaaggttat gttcttcaat tattttttta gctctttcaa
    14881 aaatttccct atcctctttt ttattactac cttctatctt cataccatgc atagaagatg
    14941 atactttaga aggaacttca atttctatat ctgatattac ctttgtacaa caagctagta
    15001 tataaccttg ctcccactca tcatctgtta tatgtcttgt tttttctgta tcaacttttc
    15061 cattcaataa ttttacttta cacttcccac aagacacgtt tccattacaa ggagcatcta
    15121 tgaatatatc tgcatttctt gcaacctcta gtaatatatc cccctcatta caataaacct
    15181 ctttattgtt tggtgtaaaa cttactttta tcatgttatc cctcccaatt tgttctatat
    15241 atgataaaag gaaagtatag ctaaatttgc gtgcactcaa attttactat actttcccca
    15301 attataataa tatcttaatc tttaattatt ctaatccagc ctcgtattct ttatcactta
    15361 ataacgtatc aagttcagcc acatcagcta gttttacttt taatatccag ttttcatatg
    15421 ggtcttcatt tatacattct ggctcatctt ctaatttttc attaacttcc aatacctcac
    15481 cattaacagg agatattaaa tcagaagcta ctttagaaga ctcaactact ccaaaatcta
    15541 ctcccttagt tacagtatct tctacttctg gtgtttcaac aaacaatatt tctcctaatt
    15601 gatcttgagc atagtctgtt atacctatat atacaacatc tccatcaatt acttttaccc
    15661 actcatgatc tttagagtat tttaattctg gtaataattt catttcgata gacccccaat
    15721 attatattat tgattaaatt acttaaatca tattaatatt atatcatatt attttaaatt
    15781 ttccatcaat tacattacac tttccatagc taatgctgga tgaccttttt cttctaagaa
    15841 agctaatact ccttcagaat cgtcagctat agtttcatca caaaccatat cacagaagtt
    15901 ttctattcca gtcatttctt taactgtagc atttaattta tcagctacat aatcttttaa
    15961 ttcttttggc atccaaacta ttctttctgg tccaccttct gcataagcga attttttaga
    16021 agatataaaa tgtcttccgt gtcccataaa tcctggagtt tgaactcctc cacctgtcat
    16081 agaagcaagt tctccgaaag tcataccaac tggagtaaca cttgcaaatt ctctgttaac
    16141 tacaacaaat ccatttgctt ctggcattat accacagata cattcgaagc atccacaaga
    16201 agtcattggg tcttctagta tagagtataa tgtaacagat tcaactgcac cttgagatat
    16261 ttggtttaca gtttcattta ctgaattcca tacacctgtt ctatcatcta agcactcgcc
    16321 tttttctatt ggttgacaag gacctgttgg gtctaattct ttagtagcct tagcatctaa
    16381 ccagctaact gctccacaaa gaccaagtct ttcaggagta acaacacaaa cgtgagctgg
    16441 tgcaaatgat tgacataagt tacaagaata gaaagtatca acactttcat caactaatga
    16501 agctaatctt tcatctctag cattgtactt agctattgct tctcctttta attcagaaac
    16561 tttttcagca tctgtaatta tagttatttc acacttatca actactgatt caaattcatc
    16621 taacatctta gcatataaaa cttctcctat atgctcaagt ctaaatcctt tatcaaatgc
    16681 atctttagag attcttaccc aagccatatc tctttgtcca acgtgcatta caccttctat
    16741 atagtttaag aagtagtgga aacgtctttc aagaactggc tcgaaatctt cttgcatatt
    16801 tttaccagct attttaacta ttacagcaag tggtaatctt aatacaccat ctgcatcaac
    16861 ttcatctata tttggcccta ttatttctat cttatggtct tcaacttctg ttgcttcttt
    16921 cttaacaaca agctcccaag cttcagttct gtttccacca aactcagcaa acatatcgct
    16981 ctttctaatt ctctcacctt caaatgctgc tgcaaatgaa actgggatag gtatttcagt
    17041 aacttttatt tttattcctc tagcttctaa tgaagtagct actatcttat cgtaatcttt
    17101 ttgagttaat aggttcattg gaacttcaag aactgtttgg tcagttataa ctgggaatcc
    17161 taaagctatt gctccagcac ctgcagatac aactaattca cttaatggtc caaatgcatt
    17221 aacaaatgca ggaactctat tagctgtgta ctctaataat ccgtttaaat caccaggagt
    17281 taatccaccg aatattaatg ctgctcttac tgcaacagat acaacgtgta taacagaagt
    17341 tacatcatat cctagaggta taactcttag ctcaagaccc atttttactc cagcttctat
    17401 agcttggtct ataactttac caactaagaa agttagtaaa cctttagatt ggtaatcttt
    17461 tataactttt gctgctgatt ctgcatctgg acactcacca agaacaactg caacaccagg
    17521 tatatctcct gtaactaatg gtacaccaag tgatctgatt atagggtcag ttatatgacc
    17581 tgcacatggc tcactatatg gagcatccat agttgaatat tttaatgctt caattacttc
    17641 tgctgctaaa gctgtagcta aaccagcatt aaaagcatgt tctagtaaat gagttctatt
    17701 tattaaagat tttactactt ctaaagcacc ttctaagtcc cctaaagtgt tcatcttttg
    17761 tcctgttgca gcatatatac aaggtaatga atatgctgta tcagggaaag caactttatg
    17821 ctcttttcca ttcttttcta tagcttcagc taacatagct tgagccgcac ctaaagcttg
    17881 ttctgaccct gtaaagatta tattatatag attcattcta tttccccctt taatatttac
    17941 acctattttt tattaactat accctaaaaa ccctagaaag caaatccacc ttcatttaac
    18001 tctaagaaag agtctgcata taaagatgcc ccgttgatta tgtcacaaga ttttacagtt
    18061 ttcattaatt ctgggtcaca tggattcatt atagctgaac taaatccatt agccattgcc
    18121 attgctaaga atgcactatc taaaacaggt ctaacatgct taggacatcc attagatacg
    18181 ttagataatc ctcctgtagt taaaagtccc atctcagtca tcatttttat agcttctaaa
    18241 acttctactt gtttttcttg catacctttt ataactaagc ataatgggtc aaatagtata
    18301 tcagttggct ccattcctaa cattaagcct ttttctaata tttcttggca gtaagccata
    18361 cgctcatcat tatctcttgg gataccttct tttgcacata aacctataac cattgcttcg
    18421 tattcagctg ctatatctat taaatcaaat cttgagccag catcagcaga gtttattatt
    18481 ggttttgcat tagttctatc ataaacttta agtccagctt cgatagcttt tttattagct
    18541 gtatctaatg ctataggaac attgttgaac tcagattgaa gtaatttgat tccccatgtc
    18601 attatttctt cgccatctct ttcggcaggt cctatattaa aatctatata gtgtgctcct
    18661 gcttctaatt gctcttttgc tctttttaag attggagctg ggtctctttc tgctaatgct
    18721 tttcttattg aaggtgatat acaatgtatt ctctcaccta taatcataaa tttttccatt
    18781 tataatgtcc ccctttaaat ttaatattaa tagttagtta atattttatt agtttgtttg
    18841 gcatgctttt tcttggtatc cttttaagaa cttaggtaat tccatagatt cctctggtcc
    18901 tataactaca ttccatcctg gtaagttatc ttctatatca cctttaagta ctgcaacttt
    18961 tcctggaatg ataaggtctt tacaattagt tacttcttct actttacttt ctttaatgaa
    19021 agcagagatt gagtttccac caaatttacc agcagcccaa gatgtaagaa ctgaatatcc
    19081 acctgcatct ggtattacta accatactgg aacttttgat ctttctatat caccagcaac
    19141 tatgaagtaa gttaatgcaa agtcaacagt aactaatact ggagaatttt catctggatt
    19201 gttgattgga taaatctttg gttcaactct cattggtctt tgtgggtcag tgtatatgtt
    19261 ttgtcttagt gcaaataatg gtaatgcctt agcataacta atatcatcta ttactattat
    19321 agaaccgtat tttatagtga atattgatga taaagcaact tccatcatag ggtttgaatt
    19381 agataatcta tttgcaaata ctattgaagg atatccaaat gttctatctt gctcttttaa
    19441 agctgttctt ctaacttgta tagcattagt gtaagtatct tttatgtttt ctcctgttac
    19501 atctaatact aattctttat atccagcggc ttgaattaat tcaactgttt catataattc
    19561 ttctaagcta ccagctttta cacctaatgg taaacttgct cctttaacta cttctatcat
    19621 atctttgtag ttctctttag ttgctccata taccattggt ctagcatctt ttaatacttc
    19681 aacagcttct ttaactactt gtgcatcatc acaagctaaa atataagcta cttctaatcc
    19741 actgcctttt attttatcta ttaattttaa atacgcatct ttatctccac aatactctaa
    19801 aacagccatt tcaactttca tttgttcacc aattcttaca tagtcaactt ttttcatgtt
    19861 agctatttta gcatctactg cttcatcact catacaagta cagaatgaaa ctgcatatct
    19921 atttctactt actaatgttt tttcatgtct aaataatact gtttctccac ctagttcata
    19981 ctcagatgca ccagcaccaa cttttaaagc tttcattaaa ggtgcagtag cctctgataa
    20041 ttttgctata gcgtcatcag acatatgtgg gcatttacct acttctacag ctcctgaagc
    20101 aaccttcata gagaaagcca tacaagttgg gaatccacaa tccttacagt ttttctttgg
    20161 tgttaattta aatatatcta aagcttttaa tgccattatt ttttccccct aaccttaaca
    20221 atttaattaa gctaatgcgt taaccaattc ttttatagtt tctattgatt ttggatgacg
    20281 aagtataact gcgtttgaac cacctactaa aacacttgct gcagttgaaa cttccattgc
    20341 tatagttctt tcttctggac aaccccaatc tggctcatct tctattggag ctatagcttc
    20401 tttaacatga cctacttcaa aagctactgg tgttatgata ggcatttgta atgtcttatc
    20461 attttgacca aatgctgcaa gtctaattct atccatagta gatgcaacgt actcatatcc
    20521 ataaccaact gctgaacatc caacattcat aactatattt tcacctttaa cgcctagttg
    20581 agttaacaat acgtttaatt gtttagctag gtttatatca acagaagatt cagctcctac
    20641 tttatgtgca taagccatac cagctgatgc tcctactcct ttgtagttat cttctactgc
    20701 tgacataaat aagcagttat gtccatccaa tgtttgagct aatttttcaa ataatttacc
    20761 atctttttca tgatttcctg aaccagctac aactaaaggt aattttattg cttcaattac
    20821 tgccttagct acatcagcac attcatcaac tgacttatct aatccatttg ggtcagaacc
    20881 atcaaatttt aaacaaataa aatctgcttg tgtattagct tcaacatatt tagcccactc
    20941 tactggacaa ttagctacat ctttgtataa ttccttatat gaatcagtcc agctttcagg
    21001 ataaacgtct gatatttgta tacctatttt tggagaatta cctacttctc catcaaaact
    21061 ataaaaaggt aatacatttt ccccacctaa tttaattgct ttttccccta ttcctacttc
    21121 aacttctgat atttttccag aatatttttg agtagacatt ttaaatgcca tatttttttc
    21181 ccccttaagc ctattttaat tctaatttag caaaaatttc tttcatagcc actttagatt
    21241 ttgaatcttc aggtaaatta actaaaggaa tacctgtaga atcatattca tatatcaatt
    21301 catccatagg tacaacaccg attagctcta ggttatgctt ttcaatttct tctttaacac
    21361 catcattcat aaccccattt ggaactttat ttacaatcaa aagtattctt ccaacactta
    21421 actttagttc ctcagctaaa tctcttattc tagcaacagc ttgtatgcta cgtcttgagc
    21481 aatcactaac caataaaagt gtatcaacat gtctagtgac ttttctactt agatgttcca
    21541 taccagcttc gttgtccatg actaagtatt tgtaatgacc agatattttg tttacttgtt
    21601 ctctaagtat cccatttaca aaacagtaac atccttcacc ttctgaccta cccattacta
    21661 ataagtcata tccttcgcct tcttcgatta tagaatttaa tctaaattga agatattgtg
    21721 cctttgtcat accaccaggg aatgcattgc ctaacttttc tctttgattt acttcttctc
    21781 ttatttctcc tattgttgct tcaacttcga tacctaacac ttcatttatg ttagcattgg
    21841 catcagcatc tacaactaat actggtccct ttttgtcctt aaccaaataa tcaatcaaaa
    21901 gccctgtgag acttgtttta ccagttccac cttttcctgc aacagctata ttgtatccca
    21961 ttttaagact tcccccttaa atctagccac agagccttat gtactctgtc tgtctattat
    22021 aatttaggta cagaatgaac acattctcca tgtacatcat gaagtgcttc cattagccct
    22081 tcagataaac ttggatgtgg atgtattgca tcccctactt gttctactgt taatcctaga
    22141 tgaacagcaa gtgacaactc tgtcaataaa tctgtagcat gaggtcctac tactgctgca
    22201 cctattatct tatcagtttc tttgtcagct ataactttta caaatccttg gaaatgtcct
    22261 atagcttgtg cttttccaag acctctaaaa tcaaattgac ctacattgta ttctacacct
    22321 tcagcttcaa gttgcttttc agtcttacca acaccagcaa cttcaggttc agtataaaca
    22381 catcttggaa ttgctctata atctactacc ttagtcttac ctaaagcatt ttcaactgct
    22441 acgatacctt ctttagaagc aacatgtgct aggaaaggag tatctattat atcgcctatt
    22501 gcgtatatac cttctacatt agtttcaaga tgttcattaa ctactacttt tcctctttcc
    22561 atttcaattc ctatatcttc tactccagaa ttgtcaaggt taggtcttct accaacacat
    22621 actaatgcat attgtgcttc tataaccttt ccattagaaa gagttgcaac agccttacca
    22681 tcaactactt cacaagtttg tactccaata cctgtaataa ccttaatttt atctttctta
    22741 aattgtctaa gtagttgttt agctacatct ttgtcttcat ttaatagtat ttggtcaacc
    22801 atctcaacta tagttacttc tgttcctaag gctctaaaga actgccctat ctcacatcct
    22861 ataactccac cacctactat taacatagac tcaggtatct cttcaagtcc aagaacttca
    22921 tcactagtta ttacaacttt tccatcatat gggaacattc ttggtacaac tggaacagaa
    22981 ccatttgcta gtattatctt atctgctttt atagtttcta ctgttccatc atctttagtt
    23041 acttctatag tgtttttatc aattaatttt ccaaaaccat taactaagtt tactcctctt
    23101 ttttcaaata agaactctat accacttatt aattggttta caactttatt ttttctttcc
    23161 attatggcag tgaagtttgg cttaattgta ccatctattt ctataccaaa atcctttgct
    23221 tcttttacag tattcaatac tcctgaagaa gcaagaagtg ctttagttgg tatacatcct
    23281 gcatttaagc aagttcctcc aactcttctt ttttcaacaa ctgttacatc tgcaccaagc
    23341 atagaagctt ttatagctgc tacatatcct cctggtccac cacctactac tactatcttc
    23401 atctttaatt cccccaaacc taatataatc tacaatcttg caatactata aacctgcggc
    23461 atccagtata gcaggtatat tctcttctgc cccaattgcc attatatgaa caccatcaca
    23521 taaatcttct tcttttaatt gtttgataag ttcccctgcc atttttattc cttcacttac
    23581 ccagttttct tttccagctg ctcttaatct ttcgatttgt tcatctggaa caaatattcc
    23641 tggtacattt gcagtcataa atttagccat tcctggtgat tttaaaggta ctattcctgc
    23701 taataccttg caatccatat cccttgttaa ttctctaaac tttctcattg tatttatgtc
    23761 ataaagtgct tgtgtttgga aaaatttagc ccctgctttt attttctttt tcatttttaa
    23821 taattgaact tctattggag aatattctgg agttactgat gctcctagat aaaaatctgg
    23881 agaacctttt aacttattac cagccatgtc cgtacctgcc attaaagtct cagcagtttg
    23941 aagtatcccc acagaatcta aatcaaacac tcccttagct tgtggatggt ctcctacgct
    24001 agtatggtct cctgttagtg ccaacagatt gtttatccca aatacacctg ctgacaacat
    24061 ttctccttgt atagctattc tatttctatc tctccctgtt atttgaataa ctggctctaa
    24121 tccagcatct tttaataatt tacatgtagc aagagaagtt gctctcataa ctgccgattg
    24181 aaagtctgtt acatttgctg catgaactct tccaactaac ggctttgcac attctattaa
    24241 atgtgaaagg tcagtccctt ttggaggagc catttcagta gtaactgcaa attttccact
    24301 ttctaatgtt tctcttaata agctcatctc taatccccct tttaaccttc taaaaaaact
    24361 tttatgaatt tgctgctgct tctttctttt tctttgcact taaacttctt ggattatttt
    24421 gcttagaata gtcttttggt ggtcttattt ctgctaagtt atctaattgt cctatagctt
    24481 ctagtctttc atatatcttt atccaagcac aatcattctc tgagtttact tcacacttac
    24541 catttttagc tccaccacaa gccccattca taagaccttt agcacacata gttactggac
    24601 atatcccacc tgtccaacca agttcacagt ctccacaagc cttacaggct tcttcatatt
    24661 ctccaactct ttgtacttcc cctataaaca aagtattgtt ggctggataa actggcttat
    24721 cttttaaatt cttaactatt gtctgtgtac catctccaca tgctaaagat aaaactgcat
    24781 cagcttcctt agtctcttct tttagagcct ttaaatcctt tttagacttt aaaaggttac
    24841 aagcagggtc aagcattaca tatcctaaga tttttttgcc ttcaccttca agagtttcct
    24901 tcatttttaa aacttcttct tccccaccac ttttacaagt tgctgcacat tgattacaac
    24961 caactaaaac cagcttgtca aaatctttta agtaccctag cacttcttct aatggtttat
    25021 tttcagaaat tatcatatct acttcccccc taaaccttcc acatatatat atctatttat
    25081 tgttttgtaa tttgcaagcc ttaactacat gttttgcaag tatagatgtt gtaactgaac
    25141 caacccccgc tggaactgga gttatcattg atactttgtc taaaactgca tttgtatcaa
    25201 catctccaca taaatttcct tcttcatcaa catttatacc aacgtctata actaccgctc
    25261 catctttaac aaaactttca tcaaccatct tagctctacc aatagctgct attagcacgt
    25321 ctgcctctgc tgctacacct gatagatttt tagtttttga atgacatatt gtaacagttg
    25381 cgtgttcact taataaaagc attgatactg gctttccaac taccattgat cttccaagaa
    25441 ctgttacctt acttcctttt aaatcaacat tatagtgttt taatatctca actactgctg
    25501 taggtgtaca tggtggaaat ccacttttat ccccttccat taccttagca gagtttattg
    25561 gactaaaaca atctacgtct ttttccggtg caataacata ttttataact tcttcattta
    25621 agtgttttgg aagaggtcta aaacataata taccattaac atttttgtca tcattaactc
    25681 tctttaatac atcaatatat tcctcttgtg ttatatcctc agctaactct aacacttctg
    25741 ttgttatacc tatgttttga catctcttta gtgctcctct ttcataagat aaatcatcac
    25801 ttcttgcccc aactctaact attgttagtt taggatttat accttcttta attagtaaat
    25861 cgacttcttt tattaattct tcactaatct tatcagctac aggttttcct tttataattt
    25921 gtcctttagt tgacattcct tccatacatt cacaactccc ctacaagcaa acttaaatta
    25981 atttattcta tataccacat attaataaca tagtatctac tttcgtcatt taaaaattat
    26041 tttccaagag ctttttcaac tttggcataa acttcatcac aaatttttac accatcttca
    26101 actaacttat ctacttctgt ttttacctta ttaacatatt ctttatcttg tatagaattt
    26161 atatttataa ctacatttaa ttgtccacca agtatagcag ctcttaaaca ctgaactcct
    26221 acaccaacat cacttatagc aagtcttgaa cctttatcaa ctaaatcttc atgtaactta
    26281 atagcttcat agcaaactct tactatgttt aatggtactt cacaagcaac ttttaatgcc
    26341 ttttccattg tttctgcttt tattcttttt tcttcttctg tttctttagg aagcccgtaa
    26401 gcttttgata atggtaagaa acattctgca tcatcatcta tcatttttaa taaatctttt
    26461 tctaactttc ctgccttact taatatctct tttacacttt cttcatactc agcatacttc
    26521 ttcttcccta ttgtaaggtt acataccata ctacctaaag ccatacctat tgcacctact
    26581 agtgcagcag ctcccccacc acctggtact gcttctttgg aagatagtac ttctacaaaa
    26641 tcaacacaag ttttatctgc tattttcatg ataatcctcc ttgaaaggat gtaggaaaat
    26701 atctcaaatt gttcgagata ttttacgaac tattttaaga tatctcctac tctttattta
    26761 taaattaatt tccttagaat aatccagcta ttactccatt ttcatcaaca tctatttttt
    26821 ctgctgctgg aacttttggt aatcctggca tcttcattat ttctccagta agtgcaacta
    26881 taaatccagc tcctgctgaa attgttgctt gtcttacagt tattctaaat cctgttggtc
    26941 tacctaattt agtttggtca tcagttaaag aatattgagt cttagccata catactggaa
    27001 ctttagtaaa tccaagtttt tctaagttag ctatttcctt atcagcttca ggagtataat
    27061 ctacaccatc tgctccataa atcttagtag ctatagcatt tatcttgtct tttatagata
    27121 aatcatcttc atagcagaat ctaaagttat tttcttcttc atccaataat cttaaaactt
    27181 ctttagctac tgcaattcca ccttctccac cttttgccca tacttcagaa agagcaacat
    27241 taacacctaa ttccttacac ttgtcttcaa caagtttaag ttcagcttca gtatcaagtg
    27301 ggaatctgtt gattgcaaca actgctggta atccatatac ttgagttatg ttttcaacat
    27361 gttttaataa gtttggaagt cctttttcaa gagcttctag gttttcgtta tttaagtctg
    27421 ctttagcaac tccaccattg tattttaatg ctcttacagt agcaactatt ataacagcat
    27481 ctggttttaa gtttgccatt ctacatttta tatctaagaa tttttctgct ccaaggtcag
    27541 caccgaaacc agcctcagtt attacataat ctgcaaagtg catagccatt cttgtagcta
    27601 taacagagtt acatccatga gctatatttg cgaatggtcc accgtgtaca aatgatggtg
    27661 ttccttcaag agtttgaact aggtttggtt ttaaagcatc ttttaataat gcagccatag
    27721 caccattagc ttttaattgt ctagctgtta caggttcacc ttcgtagctg tatccaacta
    27781 ttatgtttcc taatctttct tttaaatcag atatatcact tgccaaacag aacgctgcca
    27841 ttatttcaga agcaacagtt atatcgaatc catcttgtct aactgctcca tcaccttttt
    27901 tacccatacc atcaacgata tttctaagtt gtctatcgtt catgtctaca catcttctcc
    27961 aagttatttt cttagggtct attctaagtg catttccttg gtgaatatgg ttatcaagca
    28021 tagcagctaa aagattgtta gcagctccta tagcgtgaaa atctcctgtg aagtgtaagt
    28081 ttatatcttc cataggaaca acttgtgcat atcctccacc agctgctcca cctttaacac
    28141 caaatactgg tcctagagat ggttctctta aagcaactaa tacatttttg tctagtttag
    28201 caaatgcatc agcaacacct atagtagtag tagtttttcc ttcacctgct ggagttgggt
    28261 ttatagctgt agttagtatt aacttagctt ttttaccagt ctctcttttt agtagattgt
    28321 agtcaacttt tgctttgtat ttaccataaa gttctacatc atcttcacct agtcctaatt
    28381 tttttgcaac ctctctaata tcttgaggct tagcttcttg agctatttca atgtcagatt
    28441 taaatcccat aactgaatct cctcccacaa cctaaataga tttaaaatat aatttttgta
    28501 aaaattgtat taatatgtaa aaattatatt ttataagata attatacatg taaaattact
    28561 taaaaactag ctactaagct attaaaatat tcaaacttaa tagctagtta tttatctaat
    28621 tacttactta ttacctatct attgcctatg tctaaccttt aaccaactta aaatcccaaa
    28681 tcaaaatttc tatctatttt atttatcctt aagtgacatt aatttatctt ttattgcttt
    28741 aatctgttct ttcgttgttt cactagaatc atatggagat tgattagctc tatcagaatc
    28801 aataacatct tggttataat aaataaatcc taaagattct ccatcttcta agttttggat
    28861 tataaattct tcatcttcct tatttctaat tttatttcct actacaaata ctttatttac
    28921 acctatatca tgtccaagtt tcttaacttt tctataagtc tgtagacttc tctctcctgg
    28981 ttctacaact actataaaag catctacacc ttgggctgtt cctcttccta agtgttcaat
    29041 tcccgcttcc atatccataa ccactacatc tttattttgt agtattaaat gtgagcagag
    29101 tctcttcaaa agaacatgct ctggacatac acatccagta ccaccagaat ctacggttcc
    29161 caatgtaagt aatcttactc cattgtattc tttacagaaa ttttcaggga tatcgtctac
    29221 tttaggattc atcttaaaca tttttccaaa tgaacctaca gaagcagctg ttctatctga
    29281 aactaatttt ttcatttctg atataggtac tattgattca tatacttctt ttggaaaacc
    29341 tagtgctaaa gctaaattag catcagggtc ggcatcaaca gcaacaactc tgtatccgtc
    29401 ttcagcaaac atcctagaga gcattgaaga aaaagtcgtt ttacctactc cacctttacc
    29461 tgttattgct atcttcataa tccctaccac cttttattac tatttgcttt ttagtagtta
    29521 attttacagt taaatatttt ttatactcta tatttttata cactaaaaat aaactacagc
    29581 tagtccttac aggaaccaat taaatttacc ctactagctt ttcaaagcag catgtatagt
    29641 tttattattc tttaatattg tttatatttt atttattcag tatattcatt atattttgat
    29701 gttctttact ttaatatttg actttattca actttattca accagaaact tcttataaaa
    29761 acgtttattc tataacttca ctatttttta agcttcagcc ttttctgcca tcttttcttc
    29821 aactaatgct tcaaagtgaa cacgtttttt ctctatatct tctattattg tagctgctaa
    29881 ctcttttgga tttgtattta cagtaaatgt agctccaact ttatctttta attcactagt
    29941 taatatatcc actgctcttg aagaaccagc tattggaggc attattccta aataagtgtc
    30001 tataccagaa gctacaacat agcatcctat agcaactgct ttttctgaca tccactctgg
    30061 agctatacct acaactggaa ggtcacacat atccatatct aagtaattag ctgctgctcc
    30121 aactaaatct agtatacgac ttatatcaac acaagaaccc atatgtagta ctggtgggat
    30181 tcctactaat ttacagacag ttgcaagacc tttacctgca tatttttcag ccgcatcaga
    30241 ttccattaaa ccaaacttag ctgctgctga agctccacaa cctgtagtaa ctactattat
    30301 gtcgtttttg attaattctt tcattattgt tacgtgagcc tcatttgaaa ctcctttagc
    30361 attgttacat ccaactacac cagctgctcc tcttaatact ccagatttta aacagtctgt
    30421 taatggctta actgttcctg ctgggtctat atgagagttt acaactctgt ctaattgatt
    30481 tactactgct tctacactat acccaactgt tgcgcctgat tttaattcag gtataagtac
    30541 ttttgattta tctctatttt taaagtttaa aatagcttct ttaactattg ctttagcatc
    30601 atcaagtgct tgttcttctc taaattcaat ataagttgaa cctgttatct tagcttttgg
    30661 agaagttgtt acaaatttag tatggtaaca atctgcaact ctagctaatg cagggaatat
    30721 acattgaacg tcaactatta cagcttcaac tgctccagtt attattgcaa gttcttgttg
    30781 atggaagtct cctgctattt ttacaccatg tctcattgta atctcattac ctgtacaaca
    30841 catacctgct aagtttattc catcagcacc aacttcttta gctaaagcta ctaagtctgg
    30901 ctcttctgat gctaaaacta tcatttctga taatgctggc tcatgtccat gtaatattat
    30961 gttaacttta ttttcttcta atactgctaa attcgcctct gttcttcttg gcactggagt
    31021 tccaaataag atatcgctta gacgagtacc tatcatagaa ccaccccaac catcagccat
    31081 agaagttcta agactcatgt gtattaaact atctatatca ccagtacatc ctatatgagt
    31141 agagtgcatt attgttgcaa tttctctatc tatagctctt ggctctatag cgtattcttt
    31201 ccatattttt tgtcttggtt ctggtgcatt ttttataaat cttaatgtcc caaaaggttt
    31261 tccaaattcc attaatgcaa tttctgccac ttcatgtgct acatcataga tatctctacc
    31321 ttctgtctct acatcccatt ctttagctaa agtaattaac ttagcttcgt ctcttatttt
    31381 atagtttcca tttggatcag ctaatgctaa tgtatgtgct atatctctag catggtctga
    31441 atgggcagct gtcccaccag caaccattct tgcaaagttt ctacctacta tagtatgctc
    31501 atctgctcca cataaccccc ttggagtctt agggcttatt ctacatggtc ccattccaca
    31561 tattctacag caaacacctt gaagaccaaa accacattgt gccttaaagc cttcttttct
    31621 atcatacatt gtttctacgc cttcttctct agctttagct atcatcttct ggctgtttaa
    31681 atcaattgtt aacatttttt catccatatt cctatcccct ttttttgatt tttaaaatcc
    31741 cccaggtgac tgacttcatg tcataaaata ataaaataaa tgctttctaa gttgattata
    31801 tactaatttt cagtgctttg ctttagattt aaatattttt ttaacaaaat tagataatac
    31861 ataaaaattt tattttctac acttaattta agttgatttt atcgcttgtt tttggctatt
    31921 tgttaatatc taaacctact tttttgatac ttcagtttaa ttaaattatg ttttgatttt
    31981 tttaaatcaa atttgaaatt tttctagtca tttttatatt attgcagatt gtttgtgtat
    32041 ttattatctt tcactactgt ttggacttat tacagatttt tactccctaa acttaattag
    32101 taaaaacttc ttagaatagc attttttgga ctaatttttt tgaatttttt tatttttcct
    32161 actttaatat taattatagc ttcaaattga acatttgtat atattcattt gaagctataa
    32221 ttatttttta tataaaactt ttttaataca gcattaattt agacattttg actatttttt
    32281 ctactttaat tcatttattt caagcgattt atcctatttc atatttttag ctacaatagc
    32341 cccatatgca atagaatata atttagattc atgtgaatca gctcttgaca ctaaaactat
    32401 aggagctttt gcacccataa ttatacctgc tgatttagag tctgccatat atgtaaaggc
    32461 tttccctatt ccattaccaa cctctattgt tggaaccaat atgatatcta catctccaga
    32521 tacttcactt ttaaaccctt ttatctcact agcttctttt gaaacagcta aatcaaaagc
    32581 cagaggacct tctacaatta cattttcacc aaattctcct tctttacaag cttttgctaa
    32641 catatctgca tctacagttg cttgcatctt aggatttact ttctctttag ctgccaaaca
    32701 tgcaactttt acagtttcca ttcctaaagc ttttgcagct tttatagaat tttttaatat
    32761 ctttgccttt tgttcataat caggagctat attcatacct ccatctgtag ttataagtaa
    32821 tttatggtat ttttctaact catataccat aacatgactt aataaactat cagttctaag
    32881 accatagtct ttatttaaca cttcttttaa tatgacagat gtatctaata atcctttcat
    32941 tacaaagtcg gcttctttac ttgatactaa tttaactgct atttctgcac actctttgat
    33001 atcatcctta tccactattt tgataccact taaatcaaat cctatttctt ttgatatttc
    33061 tcttattttg ccttcatttc caaccaatat aggagtaatt atatttcttt ctacagcatc
    33121 ctttattgcc attaaaactt ctttatcatg agctgctgct acagagagta caattttctc
    33181 tcctccctta agttgttcta aaatatcatc taattttttt atcaaaagta acccctccct
    33241 tatatatatt taactaaata ataccatatt tgctatacct tttctcaatt tattttttat
    33301 gttataaaga atttatataa ctaaaagaca gtttaatatt ttattctggg atttcatcaa
    33361 taactcttaa aagctttgca ggaacaccac ctacaatagt attttctgca acattttttg
    33421 ttacaactgc tccagcagcg ataattgcat tatctccaat agtaactcct ggaactacag
    33481 ttacattagc accaatccat acattttttc ctattgtgat tggagaagga taagttgtac
    33541 cacgtttctc tggtgcaata ccatggttaa gtgtagccaa taccacatta tgcccaattt
    33601 gcgtattatc tccaatctca atccccccct ggtcttgaaa atggcaactg ctatttataa
    33661 aaacattttt tcctattgtg atgttttttc cacaatctgt ataaaatggt ggaaacataa
    33721 aaaatgattc atctaccttt tttccaatta actcagaaaa taaactacgg acttcttctg
    33781 gttcatgata agaagaattt aacttacttg tgattttcat tgcttcatta ctcaacttaa
    33841 ccataaattc atgtatttct gatttactag aaacaggttt tctttgattg atatgtgtta
    33901 aaaattcatt gatattcatt ttatacatcc tttcaatatg tgctttaatt tatttgtaca
    33961 ttctaaataa tattttaata aaaattaatt taatttattt ttattaaaat atcattgctt
    34021 cttttagtgt aatatacaat tatatctata tcaaatatct atagtaaata cttaactata
    34081 cttaaaaagc atataaattg atataattat ataatagata agttaatatt gaggagggat
    34141 aattatggaa ataagagtat taagatattt tttagcaatt gcaagagaag aaagtatatc
    34201 tggtgcggca acctttttac atataacaca accaacactt tctagacaaa ttatggaact
    34261 tgaagaagag ttgggagtta aattattggt tcgaggaaat agaaaaatca ccttaacaaa
    34321 tgaaggtagg cttttacata aaagagcaga agaaattata tcattagttg ataaggttga
    34381 attagaattt gacaatccca atgagattat tagtggtgat atatatatag gaagtggtga
    34441 aactgaagct atgcgactta tagctagaac tgcccatcat tttcatcaaa aataccccaa
    34501 tgtaagatat caccttttta gtgggaatgc tgatgatgtg actgaaaaat tagacaaggg
    34561 actgcttgat tttggtattt taattgaacc tgcaaatata cagaagtatg attatgcaca
    34621 aattcctgct actgatgtat ggggtttact aatgcgtaaa gatagtgccc ttgcatcaca
    34681 aagcacaata aatccaaaag atttatgcaa tatacctctt attatttcaa gacagacact
    34741 tgttgataaa gcaatttcta aatggcttca agacagtaat gaaaaactaa acattattgc
    34801 aacatacaat ttagtttata acgcttctct tttggtagaa gaaggtctgg gctacgctct
    34861 gtgtttagat agactcgtca atactacaga aaacagtaat ctttgtttta gacctctatc
    34921 tcctccttta gaagctaaat taaatattat atggaaaaaa catcaaatat tttcaaaggc
    34981 agcagaaaaa tttttacttc aaatacaaaa agatttttct tctatcatgt tggatacatc
    35041 taagttggat acacctaaag aaaaataaat cataataaaa ggtgagagtg tctcaaaatg
    35101 aactttgcac tgtataaggc actctttttt atacaaagta aaatatatgt tcatcatttc
    35161 agcactaaaa aagaggctta tctctatttt gagatagccc cacttaacca ataaaattaa
    35221 atacaactta acaatatcct tacttattta ttctaagttc tcttagacaa gcaatagtaa
    35281 tttcatcttg tggatttaat tcataagctc tttctatata gtaagttgca tcatcaatat
    35341 caccattatt taaataagcc attcctaaat tgcaaagtat ttctgggtct tcctttatct
    35401 tagccgcttg ttcaaaatac tctattgctt tatctaaatt attcttataa gcctcacaaa
    35461 gccccaattc cactatagta tccacttgat taggctttat tatcaatatc ttctcaagat
    35521 acatcttagc ctgctctatt tcgcccatac ccttatatcc aagtgctatc ataaacagca
    35581 agttccacca atccatatgt tcttcttcta atggaagtaa cttctctaat ccttccttaa
    35641 acttaccttg gaatacaagt gtatatcctt cttcatattg aactttaaag tccatcttgc
    35701 ccagattctc ttgtacctca gctactaaat cagcatctaa ccctagcctt aacgcttctt
    35761 cccaagtcag cttagtcttt aaatattgac cttgattata ataatggtag cctaagtgat
    35821 aataacctaa tgcaaaattc tcatcaacat caattacctt ttcaagctta gccatggctt
    35881 caagtaagaa tgcattcatt gccttatcat ccatatcttt ttgatactgt ttagctatct
    35941 cttggcaaac aatcgcatag ttatacattg catctaaatc atctggatac attgttataa
    36001 atgcttttat atatattaaa gaatctgtat gttcaccaat ctcaaagtat tttctcgaca
    36061 tatatcccat atacgatttc aaatccaaat caatatcttt tgataaagca tttaaaaact
    36121 tctcatactc tgcattgttt ttaaacttac tatctattcc aattatatat atcattgcat
    36181 ctgctataga cattgaattt aacttatctt gagcagtctt ttcttttatc ccttttacta
    36241 atacctcatt ttttataggt acatctaatc caccttttgg cacttcatag ctttttaatt
    36301 taaactctcc accatgtttt atagttataa aagctaattc ttctgctttt tttagcaaat
    36361 atttttctat cttaaaatcc attttatcct cctaaatact taaatctcta ctttatgagt
    36421 tttagatttc tcaaatattt ttttatcatc atactcaaat aagactacat tttctacttc
    36481 tcttatttct gtatttatat cattttttaa atccacaaca ttaaatctaa atggctcaaa
    36541 atgaacatat tttattatat gtttagctgg tttatcaaca aaactaggta aatatgttga
    36601 taagttatca ttatcttgta aaaatacatg gcatctattc ttaaaatcat ccacatctag
    36661 cttattaaaa aactgtggta tatttgatgt tttacccagt gatatatagt catattttaa
    36721 tatatcgttg aatacatcat tatctatgtt gattttttca ttatagaaat ccatcaatat
    36781 tttatataac tgattctttc cttgtgccaa atcaaagtag ccattttcat caaaatactt
    36841 ggcaaaaacc tcaaagaatt taaaagggct ttttttataa aatctgccta taatatatct
    36901 catagataac acaaagtttt tagaattgta gtatctctcc agtatatctt ctatatcctt
    36961 tagcttcaaa gtttcttcat agcttatata attattgtat aaaaactcat atggagcata
    37021 atccttatat ttaaaaccat gctcatctgc aacttttctc atacctgtcc ctttaatcat
    37081 ctttaaaaag cctaattgca aatgctctat acctagatta aatacatcat taaaagaatt
    37141 ttcaaagctc ttataatctt cataaggcag tcctgcaatt aagtctaagt gctgatgtat
    37201 atttctataa gatgctacag tttgtacaac atgagacaac tttttaaaat catcccttct
    37261 acctactgca tcaagtgttt tttcattcgt tgactgaaca cctatttcaa attgaaaaag
    37321 accttcttta caatcagcca aaaactcaag catcttatca tctatcaaat acgctgtaac
    37381 ttcaaaatgg taagttgtat atccattatc atttttcata aggaaatcca tgatttccat
    37441 agccactttt ctatttgcat tgaatgtcct atctataaac tttatctgtg atactcttgc
    37501 atctattaaa gcttttaaat cactctttat cctgtctaaa ctaaaatacc ttagacctgg
    37561 aatagtagat gataaacagt attggcagtt aaaagggcaa cctcttgatg attcataata
    37621 cactattcta ttttcatatt cttttggatt caagttttca taaggactag gaatctcatc
    37681 caaatcttga agtaattcca taggcttatt cactattatc tcattgcctt gtctatatac
    37741 aagtccattt acatcattta tttccatctt tccttgcaag tgaagtacta agtctctaaa
    37801 aattaattct ccctctccat aaagtatata atccacaaaa tcatactttt tcattgcctc
    37861 ataactatca taactcactt ccggtccgcc caaagctatt ttagtattag gtctaatttt
    37921 ttttagatta tcacaaagtt taactatatc tcccacattc cagatatatg ttgagaataa
    37981 tattatatca tattcatttt tatatatatc ctttaaaata tagtccaaat cgttatttat
    38041 cgtgtattct ttcatattaa cttctatcaa atctcttaca aattctttta gatatcttat
    38101 agccaaattt gtatgaataa acttggaatt taatgttgtt aataaaattt tcaaatattt
    38161 ctcacctctt tttaagatta tactgtcttt ttgtacccct tataggttaa aatagtatat
    38221 gtaaagtcta aataatatct atataattaa tttattaatt tcaagtaatg tgaggaaagg
    38281 aagtttttta tggaattaat tgaaaaagta tctatcaact ctttatcaaa aagagattta
    38341 ctacttatta taaagtctct tgaatacact aatgaaaata ctcaaattag tgatttcatt
    38401 gaccttagga ataatatagt aaaggaatta tgttttttaa ctgacactaa ggaaaaagat
    38461 tttttagatt atctagaaaa aaatagcaca ctctaataac ctaaaccttt ttaaacttta
    38521 atatataaat acctgattta gaatttattt ttatgcttaa tatattatca ttaaaggttt
    38581 tcgacataac tgttatttga ttaaatatag ggtctattat agtattacct tcttcaagtc
    38641 ttataagact tcttgggtct atgcttttat tatatgcctt aactccaatt ttatattttc
    38701 tcaatttaac aacatattcg gacatagaaa aaataaaatc tatattatct tcatttaatt
    38761 tactatcttc acccaaaatg gataatatag atttttttat gctattaatt ccttcatttt
    38821 ctacagttct atcttccata tatacatcat atagaacatt taaaacattt aataaaatac
    38881 tttcttcatc ataatcttca gatttcaaat caatgtactt atcaattaat tgtattgctt
    38941 taatccttgc catctgaaac tttacaacat ctgatttgtc taattctata gaaaatccta
    39001 ttatcttgtc tttaatactc tgtagtaatt cgacatactc tattttacta ttatttataa
    39061 gattgtgcat aatggaatta tacaccacag aacctaataa ataatcaaat aaaagttctt
    39121 cttttttaaa ataaataaca tactttttta ttagtttaat aacctcatct tcactttttt
    39181 gaatattagt atttgataaa attagtggta ataaaatatt taaaaaattg atatttccta
    39241 ttttttctcc ataaaatcta tagtaaataa gttcatctct cagtctattt tcgtctatat
    39301 acacacatct ttgcgtttta tcatctatta aggattttgt atttattata gttaaatctt
    39361 taagagccct acttgcacta ctaaaagaag atgtgtagac tttttttagt aattcgtcat
    39421 tcataaatat atcctttctg aaaaattgaa tgtaaataaa ttgttattaa aaaaaaagag
    39481 acagcccgtt taagaagctg tcatatatag ggggatagta gtgtacaaaa atcattgtaa
    39541 tctactatct atatattatt atacgatact acttttttat atgtaaagca tcagttttcg
    39601 acatccctat attttacagt tatacaaatt gcgtactaag ttcaatttta ttctttttat
    39661 ttcaacattt tatcatgcta cattctttca ggagcgtgca ttcccaacaa tttcagagaa
    39721 ttttctaaag tttgttttgt tgctaaaact aatgcaagtc ttgcttttct tatttccaaa
    39781 ttttctacta aaattggatt gtcatgataa aatttattaa acgcttgagc taaatctagc
    39841 ataaatctag tcactatatg tggctcattt ttctttagag caagtaaaat attcttattg
    39901 aatgattcta taactctaag aacttctgca ctatcttcat cagctaatag actataatct
    39961 atatcagaag tcacttctac ttctgctttt cttaaaactg cacagcatct agcatgtgta
    40021 tactgaacat atggtccagt ctcaccatca aaactaagcg ttctttccca agagaaggta
    40081 tagtctttaa ttctactatt agataactct tggaatacta ctgccccaac acctacttgc
    40141 ttagatattt catccacatt tttagcattt gggtttttag ctagtataat ttccttagtt
    40201 ttatctatag cttgatttaa agcatcttct aaaaatacta ctcttccttt tctagtcgac
    40261 atagtacctt cttcaagtgc aaccatacca aatccaacat gaattaaatc ttttgcccaa
    40321 tcatatccca taagctcaat taccttaaac cattgttgga aatgtaagtt ttgttgagaa
    40381 ccaactacat atatacactt gtcaaaatca taagtttctt ttctatatat tgcagcagct
    40441 aaatctcttg tcatatataa cgttgagcca tcattcttag taataagtgc tggtggcatt
    40501 ttatactctt ctaaatcaac aattcttgct cctttagact cttttaaaag atttttctct
    40561 tctaatagtt cgataactct gttcatttta tcagaataaa aactctctcc tgctaaagaa
    40621 tcaaattcta tatctaaaag tttatacact ctgttaaact cttttaaact ctcatttcta
    40681 aaccattgcc ataattcttg tgcttcttcg tcaccatttt ctaatttatt aaaccatgct
    40741 cttgcttcat cttccatttc tgggtgttgt tcagcttcat catggaatct tacgtataat
    40801 tttagtaatt ctggaattgg attagactct actacttctt tttctcccca ctttttaaag
    40861 gccactatta acttaccaaa ctgagttcca tagtcaccta aatgatttat tcttatagtc
    40921 ttgtatcctt gcgaatcata tatcttatat aaagcattac ctataactgt agttcttatg
    40981 tgccctatat ggaaaggttt tgctatattt ggagaagaat attcaactat tacagtttta
    41041 tcttttccaa aatcactatg tccgtaattt tctttttcat ctaaaacttt tttaattaca
    41101 gtttctgcta attgagattt atttacaaag aaatttacat atccgcctaa ttgtattact
    41161 tttgttatct ctccacttgg ttctatactt tccgccaatt cacttgctat catgtttgga
    41221 gcttttctaa acactttggc taatttaaag catggaaaag catagtcccc catatcctta
    41281 tttggtggaa cttctataag tgcctctatc tcttctttcg ataaatcttc tattttttct
    41341 ttaaggcaat ttgatattgc caccttaaaa tcttgcattc tgttgctcct ctctacattg
    41401 ttcctggttt atattgtgct tatctcttta tgttaaatca aatttcgtgt tttttcaagt
    41461 atttcattac agtgtaaaac actttagtaa ttatgttttc tgtatatatt aaaaatacta
    41521 taattgcagt ttttaatcac actattattg attttttata agactttttt ctattttatt
    41581 gtttcttgta ctatccagtt gactttatat acttttttta atcttttatc tattttcata
    41641 cgtcaatgct aattttatat acttttcttt taatctttta ttaattttta tacatcaatg
    41701 ttaactttat ataagttttt ttaatctttt atctgttttc atacatcaat gtcagcttta
    41761 tatacttttt ttactttttt atctattttt atacatcaat attagcttta tatacttttt
    41821 ttaatctttt atctattttc tataaatctt tttcactctt aacttttatt ccttcttctt
    41881 ctaatagcct tgctgttata cctttccctg gtatcttttt acctgaaaaa ctaccatcat
    41941 atattagatt acatccacaa gaggggctac cctcttttag tattgcttcg ctacatacat
    42001 ataaatttgc tatttttaga gtttcattag cccctcttac aaagttttct gttacatcct
    42061 tattatcttt agtaattact tttccatcaa ctatctcagc aggtggtctt ggtgtagata
    42121 gaccacctaa ctgctctggg catacaagtg taaattcttt gccttttaaa tattccttga
    42181 ctttttcatt atcattatta tcgccactat atttacaatt tattcctatt aaacatgcag
    42241 ataccaatat cataaaaatg tgctcctata caaattctta atatattctc atacaaatta
    42301 ctaatgtatt cttatacaaa ttattttaat ttaacaattg ttactcctgc tccaccttct
    42361 ccatattgac cacctctttg tgattttaca tgtctatttc ttcttaaaat gtcttgtagc
    42421 cctgctttta atactcctgt acctattcca tgtattactg ttacagactc taaacctgcc
    42481 acatatgcat catcaagata cttttctact tccattatag cttcttctag gtttaaccct
    42541 ctaaggtcaa cttcattttt tacactacca gattttgacc ttataatgtt tctcgttgat
    42601 ttagttacat ttgttgaaac atctttgcgt gttttttgta aagacttaaa aggtagagtc
    42661 atcttcatta taccaatttg cactactgct tcttttctct ttttatctac tgaaactaca
    42721 ctaccatttt gatttaaagt tattacctta acttcttcac ctggctttaa gtcttttatc
    42781 tccttatttg atacctttgg aactatcata ctttttactg ttggctgaag acttcccata
    42841 gagctggtca attcttttct aagttcttct atcttacgat tcttttcttt tgaagctctt
    42901 tcttgttcaa gacttctaag ttcttttatt ataatatcta cttcttcttt agcttgtctt
    42961 ataattgaaa atgcttctga tttagctttt tcaatcatct tatctctttg actgaccaat
    43021 ttttcaagct tttcgtcata ctctactttc agtttttcaa tctcttcttt taatctttca
    43081 gcttcttctc tatcttctac tgctttgatt ctattctttt caacattctg taacacatct
    43141 tctaaagcta tgttttctgt atttatatat tctttagcac gtgaaatcac ataatcactt
    43201 agcccaagtt ttctagaaat ctcaaacgca tttgattttc cgggaacacc tataagtaac
    43261 ttatatgttg ggcttaaagt ttctatatca aattcaactg ctgcattttc tacacctggt
    43321 ttagtaagag cataattttt aagctcacta tagtgagtgg tagctataca tttagctcct
    43381 acagaattta tatcttctaa tactgctatt gcaagggcag ctccttcaac agggtctgtt
    43441 cccgctccta actcgtcaaa tataactaaa gagtctgctg ttacgttttg taatatagat
    43501 actatattcg tcatatgaga tgaaaatgtt gatagactct gttcaatact ctgctcatct
    43561 cctatatctg caaatacatt atcatataca cacatactac ttccataatc agcaggtata
    43621 tgaagtccac tttgtgtcat aagtgcaaat agacctacag tttttattgt aacagtctta
    43681 ccacctgtgt ttggacctgt tatcaccaat gtatggaagt ctcttcctaa ataaattgta
    43741 tttgctacta ccttcttttt atccagcagt ggatgtcttc cattttttat gtttaaatat
    43801 ttatcctcat ttaaagttgg ttctattcct ctcatctgta tagaaagttt tccctttgaa
    43861 aatgcaaagt ccaatcttcc aagtatctct tgattagaaa ttaagtcttc actaacttct
    43921 ccaaccatag cagaaagctc tgataaaatt ctttctattt cttcttgctc acctagtttt
    43981 aactgtctca attcattgtt catctctact atagtcattg gctctataaa aagtgtcgca
    44041 ccagaagatg actggtcatg cactatacca gctacttgcg acctatattc agattttaca
    44101 ggtactacaa atctatcacc tcttagagaa attattgcat cttgtaagta cttttgataa
    44161 gtagttgaac ttattattga atttaatttt gacctaatgg attgattttt ttgggctatt
    44221 cttcttctga tatctctaag tgtacttgaa gcattgtcag atatttctac ttcactaatt
    44281 atagcattgt atatctggtc ttctatgtcc ttgtatacat atagagaatt tgatagagat
    44341 tgtattattg gataattaaa atcttcttca tcactactag ataagctatt tcttaatctt
    44401 ctagccactc ttaaggtatc tgctatcata atcagacttc ctgggtcaag agaagcacct
    44461 atataagctc tctttacctt atcttctata tcatgaatac cttccaaccc tactgaacct
    44521 ctctttataa taattgattg agcttcacta gtttcttcta gcatagattt cacttctaca
    44581 aaatcagtat ttggtactaa attttctata tattttagac ctaaagaaga tgaggctttc
    44641 ttctttaaca aatctattat tttattgtat tctagaactc ttaacgattt ctcattcatt
    44701 ttctatattc accatcctcg atattttaac ttttttattt aattttaaaa atgtatgttt
    44761 tcaagcattt ccaataaaaa ctgcaagttt tatttctttt tcatttctaa aattattata
    44821 ttttttctct tttagatata ttttacacat attttgtatt atactatgta tgtagctatc
    44881 tatatattat acataaacat gctttatttg taatataatc tgttaaaaaa tcttctttaa
    44941 tatttttaaa ggagtttatt ttagcttata aaaaaaaata gctacttata tagataaatt
    45001 aaggaggaac atgagtcatg ggaaacgtat tagaaggatt aaaaccagaa agtgttttta
    45061 aaaactttga gaaaatatct caaattccta gaggttctgg aaatgaaaaa ggcataagtg
    45121 attttttact tagctttggt aaaaatttag gtcttgaaac tattcaggat gaaagcttaa
    45181 acataataat aagaaagcct gctacaaaag gatatgaaaa ttgtccaggt gtagttcttc
    45241 aaggacatat ggatatggtt tgcgaaaaag aaaagaatgt tgaacatgat tttcttaaag
    45301 accctataaa attaagaatt gatggtgaca tgatatatgc tactggaact actctaggag
    45361 ctgacaatgg tatagctgtt gctatgggta tggctatatt agaagataat actttagagc
    45421 atcctgcact agaagtttta gttactgtta atgaagaaga tggtatgaat ggtgcagatg
    45481 cactagaccc tagcttaatt aaaggtcaat atatcctaaa tatggactcc gaggaggaag
    45541 gatacttatt agttagctgt gctggtggta aaacttgtgt tgttagttta cctgttgaat
    45601 acaaggaagt taaaggtgac aaacaaggat tattagttga ggttactgga ctattaggtg
    45661 gacactctgg tatggaaatt gttttacaaa gagcaaatgc taacaaagca atagctagag
    45721 tattaagtgt attgaatgtt gattatgaat tagcttctgt tgatggtggt actaagcaca
    45781 atgctatacc tcgtgaagct aaatgtgtaa tagctgttaa taaagctgat gttgaatctg
    45841 ctaaaaaaca aataaatgac attttaactg catttaaaca tgagtttact acttctgacc
    45901 ctggcatgac ttactcagta gctgaaactt ctgtagacaa agttcttact aaagattgta
    45961 aagaaaaagt tgttcaaatg tcttgcttaa ctcctcatgg agttcaatca gtaagtcttg
    46021 atatagaagg attagttgaa agttctacta acttcgctat aatcgaaact aaagaatcta
    46081 ctattgaatt tttaacttct gttagaagtt ctgttatgtc tattagagat gaaatcgctg
    46141 atagaataag acttttggct caagctttag gtgctaatta cgaccttata gctcaatacc
    46201 cagcttggga atttaaaaaa ggctcaaaat tagaaaaaat atgcagtgaa acttatgaga
    46261 aattaactgg taaagttcct actgttatgg ctctacatgc tggtcttgag tgtggattat
    46321 tacttgataa acttcctcat gctgaagcta tctctatagg accagatatg tttgatgttc
    46381 atactccaaa tgaacatgtt agtatccctt ctgtagctaa tgtttgggat tatgttattg
    46441 aaatattaaa atctatgaac caatattaaa tttaagtttt gattctaagt agattttaat
    46501 tttaagtaat ctatataaaa ttaactctgt aaattaatac tactgttagt ataatattta
    46561 ctttcaatat taacttatag aaataaagcc taatgataga taataacatg tatcattagg
    46621 ctttattgta atttaaatat tattaagctt tattctgttt taaaattaat tcttatacta
    46681 ttttaaatct atttcttcct tgtctcttag aatcataaag agcattatct gctatttgat
    46741 acagttcatc atactcttga ccaggctttg ctataactac ccccatacta atagataaac
    46801 tttctccatt tggcaactta atgagatgaa tatgattgta tacatcatta catttattaa
    46861 taagttcttc cttatttatt atatcattga tataaacact aaattcatct ccacccaaac
    46921 gacctactat atcatttttt gcaaaacttt catcaagtac ctttgcaaca tcaataagta
    46981 ctttatctcc taacaagtga ccataagtat cattaatcga cttaaaataa tcaatatcta
    47041 taatcaataa agcaccattt ttttcagttg ataaattcaa caaattttgt gcagttaatt
    47101 ttctaatata tgctgcatta taaatattgg ttaaactatc cctttgagcc ttatctaaca
    47161 atctattctt ttcctctttt tcagaatcaa tattacatat tttcccgatt acatacattg
    47221 gtatttttct atcattataa attatttttg aagtaactct aatccaatga aaagtatcat
    47281 caagcataat agaatacatt tcagttgttc cattttcttg tgattttatt acatcaaaaa
    47341 actttttatt atattctttc cttattttat ctctttcatt ttctatattg ccattttcac
    47401 tttccttatc atttttatcc aaaccataat aagtctcaat acccttttct ggcatagaaa
    47461 ttatcaattt atcttgctta taatcatact caaaaaagta ttcacttgtc atttcataca
    47521 actgagtatg ttttttgagt tctaaagata tcttctcgtt catacttgta cgagtatgca
    47581 aaccaaatgc cataaatcca ataatacaaa ttaataaact ggctacaata aaaatagtct
    47641 caattggatt ctgttgcata atataaagca acgagaagtc ttgtctatat gtagtatttt
    47701 ggtagacaat tgattgcatt ttttctgatg aaatacttat aatagcttta ttaaatatat
    47761 tcaataattc ttgtttatct tttttaatta taccaaaaca aatactcttt gctttataag
    47821 tttgaggaac tagacgcaca tttttatact taggttgatt catatagtac tgcatagaat
    47881 aaccttcgcc ataagtgtaa tctgcatagc ctttattaac agcttctata cactcttcta
    47941 aattatcata ccaaactata ttctcttcaa actgaccata ataattaata cctttggcta
    48001 gagctacacg ttttccatct aaactattct catttaattt attattaatc atcatagtat
    48061 attgagtaga aagaaaaggc cgagacataa ctatattatg ttcacgagag tattcataat
    48121 cataaatcat tcctgctaca atatcaattt cacgcttttt agtcatgttt tctaaatctt
    48181 cttgagattt tacaggcaca agttcaaatt ctaagcctgt tttatcacat atatgattta
    48241 acaaatcaat tgatatacct cttaattcac ctgtatcttt atctatattt tgaaatggtg
    48301 gtttgtttaa aagtactcct acttttaatt tttctgtctc tttaatgtaa tcagtttctt
    48361 catcagataa aaacatttga ttgttctctg gtgtaaagta tttttcatat aaagtagttg
    48421 aaaaatatgg gtctttctgt tcaatattat taattgctga gttaagcttt tgagttaaat
    48481 ttgtactacc tttaggagta atgaaataaa atggttttga tgaaaatttt gctacagtac
    48541 gtacaccttc tagtgggttc atactaacat taagaagtac atctgcttta ccactcttta
    48601 gtgcttctag ttgctcatca tttgttttac aatataccaa ttcaggtgac ataagattca
    48661 ttttacaata ctcatctaac tctttaagtc tagtatcaga attttctatt acagcaatac
    48721 ggattttttt cacatcttgt gaactcatta tgttatcaat atctgtattt tcatataatg
    48781 cttgtagtac tgtatttgct actccataac tatttcctgc ataattatat attttttgca
    48841 ttggctcatt gtataacata cctcccatta tatcaatttc accattttct aacatcttca
    48901 ttaattttgt aatagattca tttatctctc caggaacttg aacaaattca taattccatc
    48961 cagtatactg tgcaatttct agtaaatatt catatgtata cccaaaatag ttaccttgct
    49021 catctatttc agttaaacct ttttgaatag gataagcaac acgaatggta cgattatcat
    49081 tacctatagc gttgatacca aaagaaaata tgcaagaagt gaatatagat gtaattacaa
    49141 taattaataa aagtaatttt tttaaattca ctacacaatc ctccatatag ttaagattta
    49201 cagtataaat tactgcataa acttgtagac atgtaaaaat agattagtat ataaaaggat
    49261 atataaatct acttagaaat ttaaatatcc ttaatatata caatatattt aaattataac
    49321 tcatttatat gtctattaca acaaatttac cctgctaaat acctactcta tatcccataa
    49381 ttttacaagt tgtagtgaag tttaagttct atctcacctc aaatttagca gtgtttctat
    49441 ttacagttct tttatatttc acatctggat aacccaatat aaatgaagtg ataacagctt
    49501 cgttctcgct cattcctaac agttctttta tctttggctc tacatttgat gccataacaa
    49561 aaaatccatt ataacaaatt cctaatcctt gagaatatgc cataagttcc atattagatg
    49621 cagccagtcc tccatctaca taagcacttc cacctagaga catatctcct acaactacca
    49681 taagtagtgg ggcatcataa aataaagaat catttccgtt ctctttatat cttttgtaca
    49741 ttttcttaaa tgtattttta tagatagaac gtacagggtc attgtcatca gtatctaatg
    49801 ccaaattata aagaccttgt attgccagtt ctttcacttc ttttagcttt tcttttacta
    49861 atatgtatct tataggctgt ctattaccac ctgttggtgt gtatctacca gcttccacta
    49921 tgttttttat tttttcttct tctacctcta tatctttata ttgtcttata cttcttctaa
    49981 atttaataaa attcaataac ttttcgggtt ctaattcaaa actttcacga ttgtattcta
    50041 ttacttcatt tttatcaaat ccttgcattt ctattgcatc tgttgggcaa attgccatac
    50101 agtgaccaca gttaatacag agaatatttt taacctttgc tttatcatcc ttaactttta
    50161 ttgcatttac aagacagtct gattcacaca tcccacagcc tacacatttt tctaaattta
    50221 tgtctatcat tccaaattat tcctcctttt aaaaaattta ctttagtata aaacaaatag
    50281 ttgtctaagt caatttttat ttttttaaca atatactagc cttaactaca ctttaatgga
    50341 gaaaaatata cataaattgg aacttaaatt agaacttatt caaagtaaaa gataaaagaa
    50401 gtagatgtct aaaagtgaac tttttagtta attagatatt ctttattgta tgaaatcaag
    50461 tggatattta tcatttcaac aataaaaaag gcttacctct attttggata tgtccctgtc
    50521 aagtagacag actaaaaaaa ggctatcttt atgcactgag atagcccctt ttcccaacta
    50581 ctattgttta tcttaatatt agtcaataaa tttaatttgc tataacctgt aagttacatt
    50641 ttaatttgat gtaactttaa attacatttt taagtaatat ctttaaatta tattcttaaa
    50701 atatatcatt aaactacatt ttaattaatc taaaaactat atcttaatta atctaagaaa
    50761 cttacattat aatcttttag tttcccatta tcatatacaa tctttgcact aaagatattt
    50821 ccagtcttag cccaatttaa gaacagcctg tcaccttccc acatatttaa atcgaatatt
    50881 ttatcattat caacccaaat taaatttcct tctttacaat catttaaatc tttttcagat
    50941 aattcacctt caaactcatc tgagaaatac aaaaacatat accaatcttc ttcatcttta
    51001 aattttggaa aagttatcaa ccctttatat gacaatgatt taagagtaag accagtctct
    51061 tcttttactt ctctaattac acattcttct ggagtctctc cttgctcaaa ctttcctcca
    51121 actcctacat acttaccttc atgtatatca tctttctttt tatttctgta caacatcaaa
    51181 gtcttgtcat ctttttctat ataacaaata gttgtaagtt tcatgtatct cgccttgctt
    51241 tctctttata ttctcaacta attattttca gcactttcaa gcacatcact tatattcttc
    51301 attgcattaa gagaaagctc tgcaaattca tcaaatggaa tccctatatc ttctatactt
    51361 ctcattgcat ctctatttac atttgaagca aatctcgttt ctttcattct tttaataaca
    51421 gacttagtct ttacactggt aagtttttta tctggataaa ctaaagctat agcagttata
    51481 aacccagtta tagggtctgc tgcatatatt gctttttcca ttaggctagt tcttgtaact
    51541 cccattccat catgatgacc aagtattgct ctatacattt cttcgtcacc gaagttttct
    51601 tttttaagca gttctactgt tgttgtagca tgtccctcac atatttctcc tggctttctt
    51661 ccaactatat ctgaatccaa atcatgtaaa agacctgcca ctgcccactc ttcttctttt
    51721 tctggctcta gtcttttggc taattctctc ataacagctt caacagcata acaatgtttt
    51781 ctcattctat cagtttctaa atacttaaat aaaatttcta aagcttcttc tctcattttc
    51841 accaatcccc ctgttttttc acatatatga tatttttata tattaataca cataaattca
    51901 agtttttata tatattcatg tatatttttc atgttatatc tattctacac ctttatagta
    51961 gtgtcctgca actgttccaa tttcatctaa tttcttatac aagtctgtag ccctttttcc
    52021 aagtttataa ttattactca atacctcaat gtgagcttca ataacctttt taaccatctc
    52081 actatcttca actgtaaaat ctatcctaaa tacatctatt ccaatttcct ctaactcata
    52141 tagattgtcc aacatacaag taaccttcga attgtaaatt gtacttctac agaatatatc
    52201 ttgtgttatc ctataacttg catccgtaaa gtctcttaaa gcataactac tttccttaca
    52261 tttagcaact ctcttgtcct ttttacaatc cctaacaact actcccatag gacagtattc
    52321 tgtaaccatc ataggagcat atccatatat tactgcttca atttctacat ctgtatattt
    52381 taaagtttgt ttaatttcat ttaagtttag ttcttgtgac aaacaaactg tacttgctcc
    52441 ctcttctttg aagtggttta tactttcact attgaatgca tttaagtagc aatctatatt
    52501 taagtctttt ttcttaaagt attccataga gccccagtta ccaatttgaa ccttattaat
    52561 tccttttata ttatccaata tctcaaattg cttgtactct ttatttctaa caatccttgg
    52621 tgctgaatag attaattttt tgtcagtgac tgctgtatta gagtggttct tattcaaagt
    52681 atctatttta cttgtatttg acaaagtata tatgttattt gtatttgaac ccattagttc
    52741 tttaggaata cctaaagatg aagaagtata taaatccata gaaatacttg aatctataga
    52801 aatacttgag accatttgta aagcttttga taatgtattt atatcttcat aatagattaa
    52861 atctacatta taatttaata ctgcttctaa ttgctccaag ttcttaactt taactctaat
    52921 cttaggaact gtatcaagtt ttttctgttt atttactcta tttggctggt attttaatct
    52981 attcttctta aattttctat cttttatctt tattctttct tcatctaaaa gctcaataca
    53041 atcccttctc atctgattta acacacttat aggcatactt acaccttcat ccaggtcaat
    53101 ttctatctct tttaacttat atggtgtatt tccaagcttt tgaatttgtg tttctatttt
    53161 ttctttactt aaagccacct ttatagcttt ttcaactatt ttgtctcctt ctaccaccga
    53221 tttatttcca caaaaatcac ttataaaaag ctctggcttt ttacctagtt taatactcac
    53281 ttttgcacgt atattagttt ttatgaactc tttatcttgc tgaaatgtag cttgtactct
    53341 atccatcaat tcgctgtcag aagtcttata tataagctga tttctctttg cttctccaac
    53401 aaaatctaat tctatcaaat cccctttatg tgctattgta gttatctctc catcctttat
    53461 tattcttcca atagtacctc cacctaagtt aattccatca cctttcttaa gcgtattttc
    53521 tagcattact ctaagtcttt tgttctttct attataatct aaaacttttc caatatatag
    53581 cccttgatta ttaggtctat tagagttcat tatatcctta ccaacttcac ctaatatata
    53641 tccttttgta aactttctat taaatatggt atacaaatta tttattattt cctcagaaat
    53701 acttattttt ttcttatcta caaattcatt aatcgcttct ctatatcctg aaaccacagt
    53761 agctacatac tctggctttt tcattctacc ttcaattttt aaagataata cacctgcttc
    53821 aattatttta tccaaatctt ctatagtact taaatctcta ggactcaaca aataatctcc
    53881 attacttttt actacttctc ctgtatttat atctatcaac tcatactttt gtctacatgg
    53941 ctgtgcacac ctacctctat ttcccgacct attgcctatc atactactca taaggcattg
    54001 acccgagtaa catacacata aagctccatg tacaaaaact tctatatcta cagttgtatt
    54061 ttcacaaatc cattttatct catcaacatt taattctctt gctaaaacaa ctctatcaaa
    54121 ccctacactc tgaaggtatt ttacatcttc taaggaatgt gctaccattt gagtgcttgc
    54181 atgtagttca aagtcaggta atagtttttt tataagtctt gccattccta tatcctgtac
    54241 tattaaagca tcaatatcta tatcgtataa aaattttaca tactctacaa aatcttctat
    54301 ttcatactgt tttatcaatg tatttacagt aacaaagact tgcactcccc ttatatgaga
    54361 gtatttaaca gcctcaatca gctcatttct atcaaagtta tttgcagatg ctctagcact
    54421 aaagtcttta ccacctaaat acacagcatt tgctccgttt tgaactgctg cttttaatga
    54481 atcaaaagag cctactggtg caagtaattc tatttttttc atatttttct cctctattta
    54541 tacttgttag gttaatataa ttatatctat aacttaaata tttgtattaa atttatatat
    54601 ttcttactat attttaaatt cttcaatcaa tttatatatt agttatttat atttggttca
    54661 tttgagttaa catatacatt atttactata tttagtatat ttctattaac ttatatattg
    54721 attactgtat tttaaattct tcaattaatt tatatactgc ttactaaatt taaaacattt
    54781 taattaattt
//
LOCUS       DAYAKB010000021        54675 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.021, whole genome shotgun sequence.
ACCESSION   DAYAKB010000021 DAYAKB010000000
VERSION     DAYAKB010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.021"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            320..1396
                     /locus_tag="ACGI3L_001481"
     CDS             320..1396
                     /locus_tag="ACGI3L_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFG9197195.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1499..2341)
                     /locus_tag="ACGI3L_001482"
     CDS             complement(1499..2341)
                     /locus_tag="ACGI3L_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFG9197196.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2525..3097
                     /locus_tag="ACGI3L_001483"
     CDS             2525..3097
                     /locus_tag="ACGI3L_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9197197.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3260..3532)
                     /locus_tag="ACGI3L_001484"
     CDS             complement(3260..3532)
                     /locus_tag="ACGI3L_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197198.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3659..4531)
                     /locus_tag="ACGI3L_001485"
     CDS             complement(3659..4531)
                     /locus_tag="ACGI3L_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9197199.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4827..7934)
                     /gene="ileS"
                     /locus_tag="ACGI3L_001486"
     CDS             complement(4827..7934)
                     /gene="ileS"
                     /locus_tag="ACGI3L_001486"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFG9197200.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(8027..8259)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8434..8961)
                     /locus_tag="ACGI3L_001487"
     CDS             complement(8434..8961)
                     /locus_tag="ACGI3L_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFG9197201.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8996..9781)
                     /locus_tag="ACGI3L_001488"
     CDS             complement(8996..9781)
                     /locus_tag="ACGI3L_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmH/Sll1252 family protein"
                     /protein_id="HFG9197202.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9791..10048)
                     /locus_tag="ACGI3L_001489"
     CDS             complement(9791..10048)
                     /locus_tag="ACGI3L_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFG9197203.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(10067..10525)
                     /locus_tag="ACGI3L_001490"
     CDS             complement(10067..10525)
                     /locus_tag="ACGI3L_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFG9197204.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10565..11269)
                     /locus_tag="ACGI3L_001491"
     CDS             complement(10565..11269)
                     /locus_tag="ACGI3L_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFG9197205.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11279..11914)
                     /locus_tag="ACGI3L_001492"
     CDS             complement(11279..11914)
                     /locus_tag="ACGI3L_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HFG9197206.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12295..13335
                     /locus_tag="ACGI3L_001493"
     CDS             12295..13335
                     /locus_tag="ACGI3L_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFG9197207.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13798..15156)
                     /locus_tag="ACGI3L_001494"
     CDS             complement(13798..15156)
                     /locus_tag="ACGI3L_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008624114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HFG9197208.1"
                     /translation="MVNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREK
                     IYNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDK
                     AAEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMD
                     AVKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGV
                     SGPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSL
                     APTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIP
                     VSEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGM
                     INNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSF
                     KN"
     gene            complement(15179..15448)
                     /locus_tag="ACGI3L_001495"
     CDS             complement(15179..15448)
                     /locus_tag="ACGI3L_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFG9197209.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15738..17693)
                     /locus_tag="ACGI3L_001496"
     CDS             complement(15738..17693)
                     /locus_tag="ACGI3L_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197210.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLKDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKLVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17876..19351)
                     /gene="spoIVA"
                     /locus_tag="ACGI3L_001497"
     CDS             complement(17876..19351)
                     /gene="spoIVA"
                     /locus_tag="ACGI3L_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HFG9197211.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19523..20818)
                     /locus_tag="ACGI3L_001498"
     CDS             complement(19523..20818)
                     /locus_tag="ACGI3L_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HFG9197212.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDESGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERCKELIEMNNNSNENTTKVS"
     gene            complement(21002..22447)
                     /locus_tag="ACGI3L_001499"
     CDS             complement(21002..22447)
                     /locus_tag="ACGI3L_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9197213.1"
                     /translation="MSLNKFEIGGITVKKKIGFWDLVFMNISALFGIRWIAKSTASSF
                     GLGLGSIPVWLLFAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLN
                     WTSKIFWYSSFLTFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGK
                     FFTNTGALGSTIPAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAII
                     FALSGAETTANFITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAAST
                     GILDALAKVAQDLGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQ
                     LTVTNKYNIPSNAVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFT
                     SYIRLRKTRPNEERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYE
                     IEMIGGGLFVIITGLMLWKNYEKKISNNSGC"
     gene            complement(22463..23602)
                     /locus_tag="ACGI3L_001500"
     CDS             complement(22463..23602)
                     /locus_tag="ACGI3L_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFG9197214.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23921..24571
                     /locus_tag="ACGI3L_001501"
     CDS             23921..24571
                     /locus_tag="ACGI3L_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9197215.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24728..25747)
                     /locus_tag="ACGI3L_001502"
     CDS             complement(24728..25747)
                     /locus_tag="ACGI3L_001502"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFG9197216.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25778..26392)
                     /gene="plsY"
                     /locus_tag="ACGI3L_001503"
     CDS             complement(25778..26392)
                     /gene="plsY"
                     /locus_tag="ACGI3L_001503"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFG9197217.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26427..27752)
                     /gene="der"
                     /locus_tag="ACGI3L_001504"
     CDS             complement(26427..27752)
                     /gene="der"
                     /locus_tag="ACGI3L_001504"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFG9197218.1"
                     /translation="MSISRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRI
                     FAEVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAA
                     DKEIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLD
                     EIVENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAID
                     TYFEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTE
                     QDTKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAK
                     TNQRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTD
                     IRPPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27780..29108)
                     /locus_tag="ACGI3L_001505"
     CDS             complement(27780..29108)
                     /locus_tag="ACGI3L_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HFG9197219.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29346..29546)
                     /locus_tag="ACGI3L_001506"
     CDS             complement(29346..29546)
                     /locus_tag="ACGI3L_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197220.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29548..30480)
                     /locus_tag="ACGI3L_001507"
     CDS             complement(29548..30480)
                     /locus_tag="ACGI3L_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HFG9197221.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30525..31457)
                     /locus_tag="ACGI3L_001508"
     CDS             complement(30525..31457)
                     /locus_tag="ACGI3L_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HFG9197222.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31512..32801)
                     /locus_tag="ACGI3L_001509"
     CDS             complement(31512..32801)
                     /locus_tag="ACGI3L_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9197223.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32830..33522)
                     /locus_tag="ACGI3L_001510"
     CDS             complement(32830..33522)
                     /locus_tag="ACGI3L_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197224.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33537..34298)
                     /gene="pgeF"
                     /locus_tag="ACGI3L_001511"
     CDS             complement(33537..34298)
                     /gene="pgeF"
                     /locus_tag="ACGI3L_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HFG9197225.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34295..34756)
                     /gene="nrdR"
                     /locus_tag="ACGI3L_001512"
     CDS             complement(34295..34756)
                     /gene="nrdR"
                     /locus_tag="ACGI3L_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFG9197226.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34778..35041)
                     /locus_tag="ACGI3L_001513"
     CDS             complement(34778..35041)
                     /locus_tag="ACGI3L_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HFG9197227.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(35145..35918)
                     /gene="sigG"
                     /locus_tag="ACGI3L_001514"
     CDS             complement(35145..35918)
                     /gene="sigG"
                     /locus_tag="ACGI3L_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HFG9197228.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(36010..36732)
                     /gene="sigE"
                     /locus_tag="ACGI3L_001515"
     CDS             complement(36010..36732)
                     /gene="sigE"
                     /locus_tag="ACGI3L_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HFG9197229.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36757..37602)
                     /locus_tag="ACGI3L_001516"
     CDS             complement(36757..37602)
                     /locus_tag="ACGI3L_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HFG9197230.1"
                     /translation="MVYIEYYVIENLVINYIIISCTSILTKRYNPKKNKLLGASLGGA
                     YSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLVNIFISGSTY
                     FIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTININLLEKSFCC
                     KALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQEIIGSLDDK
                     TSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDREYGAIMNPN
                     ILPGF"
     gene            complement(37919..39193)
                     /locus_tag="ACGI3L_001517"
     CDS             complement(37919..39193)
                     /locus_tag="ACGI3L_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFG9197231.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39477..40634)
                     /gene="ftsZ"
                     /locus_tag="ACGI3L_001518"
     CDS             complement(39477..40634)
                     /gene="ftsZ"
                     /locus_tag="ACGI3L_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFG9197232.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40824..41177)
                     /locus_tag="ACGI3L_001519"
     CDS             complement(40824..41177)
                     /locus_tag="ACGI3L_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HFG9197233.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41276..41950)
                     /locus_tag="ACGI3L_001520"
     CDS             complement(41276..41950)
                     /locus_tag="ACGI3L_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HFG9197234.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VDLFAK"
     gene            complement(41955..42653)
                     /locus_tag="ACGI3L_001521"
     CDS             complement(41955..42653)
                     /locus_tag="ACGI3L_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HFG9197235.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42676..43416)
                     /locus_tag="ACGI3L_001522"
     CDS             complement(42676..43416)
                     /locus_tag="ACGI3L_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HFG9197236.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43686..44912)
                     /gene="murG"
                     /locus_tag="ACGI3L_001523"
     CDS             complement(43686..44912)
                     /gene="murG"
                     /locus_tag="ACGI3L_001523"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFG9197237.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44930..46060)
                     /gene="spoVE"
                     /locus_tag="ACGI3L_001524"
     CDS             complement(44930..46060)
                     /gene="spoVE"
                     /locus_tag="ACGI3L_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HFG9197238.1"
                     /translation="MPKENLKKQIDIRVKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(46112..47467)
                     /gene="murD"
                     /locus_tag="ACGI3L_001525"
     CDS             complement(46112..47467)
                     /gene="murD"
                     /locus_tag="ACGI3L_001525"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFG9197239.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSDNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47486..48454)
                     /gene="mraY"
                     /locus_tag="ACGI3L_001526"
     CDS             complement(47486..48454)
                     /gene="mraY"
                     /locus_tag="ACGI3L_001526"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFG9197240.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48495..49868)
                     /gene="murF"
                     /locus_tag="ACGI3L_001527"
     CDS             complement(48495..49868)
                     /gene="murF"
                     /locus_tag="ACGI3L_001527"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFG9197241.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVIDGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(50035..52014)
                     /locus_tag="ACGI3L_001528"
     CDS             complement(50035..52014)
                     /locus_tag="ACGI3L_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HFG9197242.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(52026..52373)
                     /locus_tag="ACGI3L_001529"
     CDS             complement(52026..52373)
                     /locus_tag="ACGI3L_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197243.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52854..53789)
                     /gene="rsmH"
                     /locus_tag="ACGI3L_001530"
     CDS             complement(52854..53789)
                     /gene="rsmH"
                     /locus_tag="ACGI3L_001530"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFG9197244.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(53819..54565)
                     /gene="lgt"
                     /locus_tag="ACGI3L_001531"
     CDS             complement(53819..54565)
                     /gene="lgt"
                     /locus_tag="ACGI3L_001531"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFG9197245.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
BASE COUNT        17004 a         9992 c         5876 g        21803 t
ORIGIN      
        1 ttttaccact ttaattctaa tgatactaaa tttttaaaat tgtttcaata ttattttatt
       61 ataaaatttt atttattatt tttcattagt atataaaaag ataaaataca taactttata
      121 gacttaattt attactttta tagaattttc acaataaaaa gtcattttac ttccgtattt
      181 aatgcaaaag tagaaattaa acttaatata aaaaatatat aacaaatttt ttttatattt
      241 ctagaagaaa agtatactct tttttgttta ataatgctaa aattgatttg tattgaattt
      301 tgattaggag gaaattatta tgaaagctca aagattaaat gctgtacttg aacaaatgaa
      361 aaaagatgat atttctcaaa tgttagtaag tgaccctact tctatatttt atcttacagg
      421 agtactaatc catccaggcg aaagactatt agcattatac ttaaatttaa atggcaataa
      481 taaattattt ataaatgaat tattcccagt ttcagaagat ttaggtgttg aaatggtttg
      541 gtttaatgat actcaaaatc cagtagaaat aataactgaa catatagaca aaaatgctac
      601 tatgggtgtt gataaaaact ggccagctag attcttatta aacttaatag aattaggtgg
      661 aggaagtaag tttgtaaatt catcttatat aatagatact ttaagaatgt gtaaagatga
      721 agaagaaaaa gagttaatga gaatagcttc aaaattaaat gacaaggcta tggaacaact
      781 taaagctact gtttctggtg aacttacaga aaaacaactt gttggtaaat tatctaaaat
      841 atatgaagac ctaggtactg atggattttc atttgaccct attataggtt ttggacctaa
      901 tggagctaat ccacatggtg aacctggaaa tgcacttgtg aaaccaggag atgcaataat
      961 cttagatata ggttgtataa aagataacta ttgtgctgat atgacaagaa ctgtattcta
     1021 taaagaaata cctgaaaaag gtagagaaat atttgaaata gttcttgaag ctaataagag
     1081 agctgaagct attgtaaaac caggtgttag attctgtgat atagatgctg ctgctcgtga
     1141 ctacataact gaaaagggat atggacagta cttcactcat agaactggtc actctatagg
     1201 acttgaagtt catgataaag gagatgtatc ttctataaat acagatactg tacaaccagg
     1261 aatgatattc tctatagagc caggtatata tttaccaggt gagttcggag ttagaataga
     1321 agatttagta cttgttactg aagatggttg tgagatatta aacaaacatg acaaagaaat
     1381 atgtgtagtt ggttaattct aaaatcaatt tgataaaatt aaaaagccat ataaaaatgt
     1441 tttaaacatt tttatatggc tttaatttct caatctatga tttatttcaa tccattattt
     1501 atattgcagt tattaagatt gcaccctttg aagtatatgt ccccatcact gaaccaattt
     1561 cacagattac aacatctttg tattttacat ccttttccat aacttccctt accttttgag
     1621 ccttttctgg gcaattagca tgtcctataa ataaaacctt ttcttcttta tctttaattt
     1681 ttgactctac taaagtaatc agctttttca aactgtttcc ttcacctctt gccttatcta
     1741 taggagttac aacgccatct gcaacttgta ttatcgcctt aaaatttaag gtatttataa
     1801 tttttcctgc tattggattt attctaccac ccttaatagc attttctaaa gtttcaagtg
     1861 ttccaaaaaa tggaggatta tctttatatt tatttattat tgaaacaatc tcttcaattt
     1921 cttttccttc ttttattaat attgctgctt ttaacactaa ttgtcctatt ccaattgacc
     1981 cactaagtga atctataacc tcaactttct tgttatttcc ttccttttca aacatatctt
     2041 ttgctaaaag tgcactatta taagtcccag ataatcctga acttatatta atcactaata
     2101 cactttcttc ctgacaatgg tatgcttcta aaaatttatc aggagaagga catgatgttt
     2161 ttggtagtac tttactctca ctcatttttc tatagaaagt ttcattatct atttcctttc
     2221 cagatatata actttcttct ccaaaagata catttaaacc aacaacttct atgttgtatt
     2281 tttctattat atcatcaggt aagtcacatg cactgtccac tatcaatttt attttatcca
     2341 tattaacctc actataagat attattttat ttattcagtc ggtcgtacga ccgatttaat
     2401 tattatttta tatattgaat gaaaaaaagt caatagatat agattctcgc tttattgaca
     2461 ataaatatcc ataagcttat aatgttatta atttgttata aatatacatg gaaaggtagg
     2521 ttttatgaaa acaaataata tgaaacaggc tattttatca tctgcaacca atttaatagc
     2581 caaaaatgga gttcaaaata ctagccttgc tgatattgca aaagatgtaa atataagtaa
     2641 aggtactttg tattatcact acgcatctaa agatgatatt atatatgata ttgcggatac
     2701 tcatttagaa gttataacta gtgctatact aaactgtgta aaaaatgtca aatcaaaaaa
     2761 ttctcaaata gaaatggtta acttaatctt agagaaaata tctactatag aaagtcgtgg
     2821 tagggtacat atgtatctta tttgtgaggc aattacttca aataatgatt taaaggaaag
     2881 aataagatta aaatatattg aatggagaac tactcttaaa tctgaaattg ttgaatcact
     2941 agaaaaatat aatagtagcg aaaatgaaca ggatgctgaa tcattttctt ttttactcat
     3001 gtcaatagtt gatggtttag ttgtccaaag tttattaaaa acagaaaaaa taccttatga
     3061 aaatatagct tcttttttag ttaatcattg gatttaaact taatacttag ataattaata
     3121 aaagtgaact atttaagtta tctactttaa cagttcactt tcttatttat tctcaataat
     3181 ttttacttaa aacattcaat ttttatttaa accttcatgg aatcacaaaa taaaaatctc
     3241 ttataaattt aaaatgtttt tatttatgtt catgtgtatg cccatctgaa tgttcatgac
     3301 catgtgtatg tgtatgctca tggctatgct catgagtacc tgaaaaacca tcatcatgat
     3361 tatggtcgtg acctacacca tttacatgct catgttcatg cccatgactg tgagaatgtt
     3421 gatgtgaatg ttcatggtta tctcctccac agcatccttc tcctccagtc ccacaacacc
     3481 cacttgtatg tggattatga tgatttctta ctacaaatct ctctcttaac ataattctta
     3541 tacctcctag tatattattg agtacttcat gtaccccatt aactacagta tacatctaac
     3601 taggtataat ctcaatacat atggcatttt ttaacatata taattaacat atataatctt
     3661 aaagaaattt atccttaaaa cctccacctt ttacttcttc aacgttattg acagaaataa
     3721 aagcttcact atccatatca taaattaaat ctttaaattt acctatttca tttgcagata
     3781 ttatgcaata aatcatcttt ttcttatttt gtgtatatgc accttctgcc tccaaaaaag
     3841 tgactcctct acccatttta ttcattatca ctttggatat ttcatcatat ttatttgata
     3901 ttaaaagtat agattttttt ctatcaaagc aatcttttcc tatatccata gtaaaagaaa
     3961 ttatatacat tgtaattaaa gtgtacatca ccaatttagc tccaaataaa aaagctcctg
     4021 cacatactac aaaaaaatta ataaataaaa atgtattttt cataggtata tcatactttc
     4081 ttttcattat ggctgctatt atatcaagtc ctccagcagt agctcttgct ttaaaagtta
     4141 accccatacc tataccagtt aatgcaccac cataaataca ctgtagcata gtatcatcta
     4201 ttgggaaata tttagcaata tcttgtgtta gccccagtgc tagagaaaat agtaacatat
     4261 tgacaaaact tattagcaaa aatttattat caaaatactt tctagctata ataaatattg
     4321 gtatgttcat caagaaactt gatattccct gattaatacc aaataatttg tataatataa
     4381 cacaaattcc agctactcct ccacttaata acttggctgg tgctagatat aaatttattc
     4441 ctaaggttga tagaatcata cccaatataa taagacaata ttgtaaaaat atattattat
     4501 caatacttag ctttttactt tcaccataca tcaaaacgca cccctttgca taataaataa
     4561 accaccctgc ataacacacg ataaatttac aaataaattt atcagaagta gtttcctaaa
     4621 aatattattc atcctcactt aaacgtttat tcattaatat tctatcacat gacataaata
     4681 atttatatga tttatataga tttatttatt gtaaattttg gaatattaaa acattttatt
     4741 gaatagataa ttatattaca taaaaaatcc ctatagaaat ctataaacta atttctatag
     4801 ggattttggt taactaacta ttatttttat ttttttataa cttttatacc tgtcatatgg
     4861 tcatttaagt tttgttcctc taaagattta tcatctactc tgtttatttc taaagctaaa
     4921 gtttcagact tgatatattc attaaaatgg tcaacagcct tagcaatttc atcatcacca
     4981 cagtattcta ttactatatt atctaatact tcaaagttat tagattttct taattgctgt
     5041 actttagata taaattctct agcataacct tcattaatta actcttcagt tagcttagta
     5101 tctagtataa caaaaagatt gttttcaaca gatacattaa atccttcctt agcagttata
     5161 cctattaata ctaaatcctt attaaattca aaagcttcac catctaaatc aactgttaaa
     5221 gtctcacctt tttcaagttt attagcagtt tcatgagcat ttaatttact taatgctcca
     5281 acgaataaat tcatcttaga acctaataat ggccctgctt ccttaaagtt tggttttaaa
     5341 ctaaagttca tatactcatc taaatcctta gcaaatatta cctctttaac attaagctct
     5401 tcttttatta aatcaactac atcacttatt gtatcttcaa acttaccatc tactaacact
     5461 ttttgtaatg gttgacgaac ttttattctt tctacttctc ttgaagctct acctaaagta
     5521 actaagtttt tagctaaatc cattttttct tctaatttag tatctactaa ctcttcatta
     5581 catttaggat attcagctaa atgaacagat acttctcctg ttaagtttct atacatttct
     5641 tctgacatat atggtgcaaa tggagctata gctctacaaa gaccatgtaa caattcataa
     5701 gttgtattgt acactgcttt tttatcttct gttaattcag ttgcccagaa tcttcttctt
     5761 gaacgtctta tataccagtt agataaatca tcatttataa aatcttgtat cattcttaaa
     5821 gttttattta actcaaatat agctaaattt tcttctacat ctttcattaa attattgaac
     5881 ttagataata tccatctatc aagttctggt ctatctttat attctacaaa aaattcagtt
     5941 ggatttatat catctgtgtt tgcatataaa gtaaagaagt tatatacatt cttcatagta
     6001 cctataaatt tactttggat ttcttttaat ccatccatat caaatttagt tggagtccat
     6061 ggtggagaaa catatagtaa ataccatctt aatgcatctg ctccatattg gtcaaataat
     6121 tccattggat ttactgtatt tcctcttgat ttactcattt tcttaccatc tttatcaagt
     6181 acaagatctg gaactaaaac actcttatat ggtgcttttc ctaatacaaa tgttgatact
     6241 gcaagtaatg agtagaacca acctctagtc tggtctatac cttctgatat atagtcagct
     6301 gggaacaatt ggtcaaagtt ttccttattt tcaaatggat agtggtgttg agcaaatggc
     6361 atagccccac tatcaaacca acagtctata acctctgtta ctcttgtcat tggttttcca
     6421 catttttcac attttaagtg tatatcatct acatatggtc tatgaagttc aactgtttct
     6481 ggatttacat cttctatagc tttttcagct aattcagctc ttgaaccaac tgaatctgta
     6541 tgaccacatt cacatctcca tataggaagt ggagttcccc aatatctagt tcttgatatt
     6601 gcccagtcat ttagattttc taaccagttt ccaaatctct tctctcctac aaaacttggg
     6661 aaccatttta caccattatt attttctatt aatttatctt taagtttagt catctctata
     6721 taccagcttg gttttgcata gtatactaat ggagtttgac atctccagca gtgtggataa
     6781 ttatgaacta ctttttcttt gctatataat ttattttcag aagctagcca ttttattatt
     6841 tcaacatcta gcccatcttc cattacaaat ctaccttccc aaggagtaga tgtaaattta
     6901 ccagtttcat ctactggttg aataactggt aaatcatatc ttttacctgt gttgtagtca
     6961 tcttcaccaa atgctggtgc tgtatgaact ataccagttc catcttcagt agttacataa
     7021 tctcctactg taataaaaaa tgcttttttg tcaacttcta caaaaggcat taattgttca
     7081 tattctaaac cttctaggtc tttacctttc atttcttcta aaacttcata atcttcacct
     7141 agtactttat cagctaaagg tttagataca taatatacct catcaccttt tttaactttt
     7201 aaataatcta catcagcatt tactgttaat gaaacgtttg atggtaaagt ccatggagtt
     7261 gttgtccatg ctaagaagta ttcatcagca tcttttttct taaatttagc tataactgta
     7321 ttagttttta cttctttata tccttgtgca acctcatgac tagcaagacc agttccacat
     7381 cttgggcaat aaggaagtat tttatgtcct tcatatatat atccttcttt gttgaatttg
     7441 tttagtatcc accatacaga ctctatatag ttattatcta aagttatata tggattatct
     7501 aaatcaactt cataagccat tctctcagtc attattctcc attgtttttc aaatgagaaa
     7561 actgactctc tacatttttg gttaaattca gctattccat attcttctat ttgttgcttg
     7621 ctagtaagac ctaactcttt ctctacttgt atttcaactg gtaatccatg tgtatcccaa
     7681 ccagcttttc tctttacttg ataaccagac attgttttat atctacaaac tgaatcttta
     7741 agcgttctag ataaaacatg gtgtactcca ggatttccat tagctgttgg aggtccttca
     7801 tagaatacga aacttgggtc atctttccct ttttctaaag ttttttcaag tatatttatg
     7861 tctttccaat aatcaaaaac ttgtgcttct gcttgtttta cagaactgtc taccaatggc
     7921 ttaaatttcg ccatgtaaat caccctttcc tactaaatat tataattcca aaatttttta
     7981 ttctttcaca taaatttaaa tactaaaaaa ctcgccccct ttaaaccaaa gggacgagtt
     8041 ataaatcgcg ttaccaccct aattctatat gtaaactaaa tactagctac atataacact
     8101 ctaatagtat aacggtacta accggcacag cttagtagaa tttaatcgtt cagcctgcag
     8161 ctcaagagtg atttttatct ttataaattc attggttctc agcataccca attctctgta
     8221 aaattatcta aagataaatg tctctatcaa cgcttttaaa aatttatctg tgtttatatg
     8281 aaattctata acaaataatt tgaatagtca atatattttt gaaaaatata ataatttcta
     8341 tttttcttac atttttatcc tatttttaat ctttgttata gatttctcaa actcacacaa
     8401 ttattctaca taaaaaataa acaaattaca agcttattct aaagttgtag cagcttcatc
     8461 attactataa ttatacactg ttgttccttc aaatgcattt acacattttt catctacatc
     8521 ataaaaaatc tcatcaacac ttcttatttc atcttctaac agtgatttaa atttatttct
     8581 aaatatctta aattctttga ctaaagcatc atactctttt cttatctcta taacacggtt
     8641 attagcttgt tctataattt gtctagcttt taaatcagct tcttcaacaa ttatcttagc
     8701 ctttttatta gccgcgctac aagtgtcttc tgctgcactt tgagcagtta ttaaagtagc
     8761 ttttagtgtt tcttcaatat tttcatactt gtttacttgg tcttgatata accctaattt
     8821 ttctttaaga gctgtatttt ccctacatag agattcataa tcttccttga tgatatctaa
     8881 aaattcatca acctcttcat ctctataccc tcttaaacct tttttaaact ctttattttc
     8941 tatctcaatt ggagttagca ttacatttcc tcccagctat aatttaaatt agtccttata
     9001 caattaatct tgcttgaact tttatttttc cttttttagt aatatctcct atttgtgtta
     9061 ccttagctct tcctttgcct ctaatagaaa tcaaatcatc gttttttact attttagaag
     9121 ttgaagttat cttttcataa ttgacatgga ctttttctcc atttatgtat tttgcactat
     9181 cttgtctaga tatattgtaa ataccactta tcacacaatc taacctatct gaagatactg
     9241 taaatgatac ttctttatat tttgaagaac tattaacaat attttctctg gaaatttcct
     9301 ttacaattac attatttctt gaaacctttt ctaagtttac aattataaaa tcgcaaatat
     9361 cactacttac aactacttga caaaagctat catgtataat tatatctcca attttttctc
     9421 tttttatacc tagacccagt attgacccta agtaatcttt atgagatata tttttaaatt
     9481 tgaaattccc ttctatttgt aaaaatctaa gagtatcttc tatatcttca tattccatgt
     9541 aaaatggata aataaataca gtgcttcttt cagcttgttc ataacctcca tccacactgt
     9601 attttatttc atttgtagaa tttaatattg ctacagcatt tttcacttca tatggattaa
     9661 gaaactccgt agacttaaca tcatagtttt ttatacaact attagccttg tctatcactt
     9721 taaacatttt atttttcaag tctatatcct ttatgtgatt tgttagtttt aatttatcca
     9781 tcctatcacc ttagaatata accaatacta attgtcttag gaacatcaat aatactattg
     9841 caattaaagg agaaaaatct ataggtccat ttgtatattt atacattata gaccttattg
     9901 gcccttctat tggctctgta agattttcca aaatatcaaa aattttactt tgtcttccat
     9961 ttggaaacca agtcatcaag ctttttataa ctatcatcca tgctattata tctaaaagat
    10021 aataaagtgc aattcttatt gttcccatat attaaccgcc tttttactat ttattttgcc
    10081 aagggaagaa tgctttactt tctaattctt ttttcatatt tgcatctata tccacattat
    10141 taggagctag tataaatatt gatttagaaa ccttttgtat acttccatct aagacataaa
    10201 ctgccccatt cataaagtta aatatagatt tacgaacttc agaattagtc aatccttcca
    10261 aattcactat aactgccctt ctttgtttta gatggtctgc tatagttgca gcttcatcat
    10321 aaaccttagg ttcaactatt acaactttca tttggctagt tgtatgtaaa tttacaattt
    10381 tatttgcttt tgcagtacta aagccactgt tcatttcttc ttcttgaact atatcgtcca
    10441 tgccactttc atattcatct tcaatgtaat cttcttcttc atcaactatc caattcttaa
    10501 atttagatat tattccattt gacattatta acttcctcct taaaatttat tcaaatttga
    10561 gtaattattt tttattgtag tttctttctc caaagattga tgttccaact ctaacaatgg
    10621 tagccccttc ctctatagca atttcataat cgtgactcat tcccattgac aaaacatcca
    10681 tccctacatt agggatgttt agttctttta tttgttttga taaatcttta agacctttaa
    10741 atacacctct tatctcatct tcatcttcta taaaaggtgc cattgtcatt agacccttta
    10801 tttttatatt tttatatttt tctgacactt ctttgacaaa gtctacaact tcttctctat
    10861 caagtccatg cttagactct tctttagata tattcacttg tactaagcaa tctatttctc
    10921 tgtttatttg ttctgcacgt ttttgaattt cttcgcataa tgcaattcta tctaaagagt
    10981 gtatcataca aactttatcg attatgtact taactttatt ggtttgcaaa gttcctatca
    11041 ggtgccagtt taatttatca cctataatat catactttct agctaattct tggggtttat
    11101 tttcaccaac agaagtgatt ccttccctca ttgcctcatt aactaagtct acatcaacag
    11161 tctttgtgac tgccaaaagg gtaatctctt tgctgtctct atctactttt tttgcagctt
    11221 tatcaatttt gtttcttatc tcagacaaat tatctttaat agaacccatt attatcacct
    11281 actttatcct tatatttgtg tttatactgt taggtcttaa aattattttg tcatatagat
    11341 taacacttgt aactccattt atgtcatttt tataataatc cacaaataca gaagattcat
    11401 tctcataagt tattccttct aatatgacaa attttacact ttgtgattgt tcatcaatta
    11461 catatacacc acgtttattg tcttttgttt ttatagaagt tttaggtatt tttaaacatt
    11521 ccatctgatt atatattata tcaaattctt cgacacttgt atcctgattt gcaacaattt
    11581 ggttacttat ttttaatttt accattattt tattattatt ttcatatatt ttgtaaactt
    11641 ttgcatctag tttttgctca tgatattcaa ttattacatt ttgatttttt tcaaagttat
    11701 tagaatcttc tttactgatg tatgtagata gataattact ttggtcattg gcatcttttt
    11761 ctatagttcc ttttacatga atctttgcat caactttttc attttttaac accaacgtat
    11821 ctacattttt gctaattatc attactaata tattaaatac taaatatata agaataccaa
    11881 gtatcactaa tctggtatat tttacctttt tcaaagactc tccccctata aaattacttt
    11941 cattataagt acttcttcta aaaaatgttt attccttttt tataagataa tattttacgt
    12001 tctaataatt attttttcca tattaaattt attttttatc aatcttccta tacaagactg
    12061 cattatttat atataattgt attataaagt ataagtttaa tttacatttt atacgttaag
    12121 cttactttat atatttttat agttattttt atttttagat gcaatataaa accaattaag
    12181 atttaaaata acttttgtta tgttgacatt tatttaggta atcatttatg aattaggata
    12241 acgttatcac aacaaaagtt tatgtcctaa aaaaaataca aggaggattt tcttatgtca
    12301 gaaattttat taggaacagg tttactttta ttggttctat gttgtttcac aatttttagt
    12361 tacaaggccc catatggtat gaaggctatg ggagctctag caaacgctgc atgtgctact
    12421 ttcttagtag aggcattcaa cctttcttta cttggtgatg ttttaggtat ggaatttttt
    12481 agaagtgttg gagctgctaa tggtagtctt ggtggagttg ctgctgctat acttgtgcct
    12541 ttagccttag gtgtatctcc agtttatgca gttttaatag gattatcttg tttagatttt
    12601 tctatattat ctggattcgt tgctggatac tttgtttctt tcttaattaa gtttatagag
    12661 aaaaaagtgc cacctggagt ggatttagtg gttgtaattc ttctatgtgc accactatct
    12721 cgtcttatag catcaaatgt agacccatta gttaatagta cactactaca aattgggcaa
    12781 gttttgatag aagctaccaa cattagccct ataataatgg gaattatact aggaggtcta
    12841 ataacagtag ttggaacgtc tccacttagt tcaatggctc ttacatctat aattggtctt
    12901 actggtcttc ctatggcaat aggagcatta ggtgcttttg gttcagcttt tatgaactca
    12961 acactatttg caaaattgaa attaggttct aaaaaagata ttatatctgt tgctattgaa
    13021 ccattaaccc aatcagacat aatttcagct aatccaatac ctatatattc tactaatttc
    13081 tttggaggag ccttttctgg tatcattgta gccttgatgg gtcttgtaaa catgacacca
    13141 ggtacagcta cacctgtggc tggttttgct ataatgtttg cttataatcc agttcaacaa
    13201 gttcttataa cagctggttt atgtgcttta ttcaatgtaa ttgcaggatt tttaggttca
    13261 aaaatattca gtacctttaa agttcttact gctggtgaaa tacgtggtac tgatgtagaa
    13321 gaagaaattg cttaaaaaac aataagattt ataaatttat atctcaagta gtagagtttt
    13381 atattgtagg caattttatt aattgcaaac gttttatttt ttatttatgt ttatgattat
    13441 tatgtgtgtt gaatatttag ataaattttt atttattatt tttatttaga tttttgttta
    13501 gttttttatt tggttgatat attaggaata aaaattagta tagtttatta ctagttagat
    13561 ggcataactt tttagataca taaaaaattt tatattaatt agatattatt aaaataaaag
    13621 cgatacatga atttttaaat gtccatgtat cgctttattt ttgccataat cttaataact
    13681 gatttttaaa gtttattatc ttaacaaagt tcattatctt atataatatt taaatgcata
    13741 ggcttcttta atttaaccat ctaaatattt aattaaatat tattatatgt aatataacta
    13801 atttttaaat gaatgtatag gagctggaat ccttcctcct ctttgagtaa ataattcaga
    13861 tgaatttgta tttataggca ttactggtgc tcgtcctaaa agtcctccaa attctaccat
    13921 atcacctaca tcacatcctg gggctggtat aattctaacg gctgtagtct tattattaat
    13981 catacctatt gctgcctcat cagctatcat ggctccaagc gtacctgctg tagtatttcc
    14041 tggcacagct atcatatcaa gacctacaga acaaatagca gtcattgctt caagcttatc
    14101 tatacttaaa gcacctttaa taacagcatc aatcatacct gcatcttcag atactggtat
    14161 aaacgctcca ctaagtcctc caacatgtga acatgccatt actccacctt ttttaacagc
    14221 atcatttaaa agtgctaatg ctgctgtagt cccatgagta ccaacaactt caagacccat
    14281 ttcctctaat atatttgcta ctgaatcacc aatagcaggt gtaggagcta gtgataagtc
    14341 tattatccca aatggaacat ccaatctact agaagcttcc tttgccacaa gttgtccaac
    14401 tcttgtaatt ttaaatgcag tctttttaac tgtttctgaa acaacatcaa aaggctctcc
    14461 ctttactttc tctaaagctc tcttaacaac accagggcca cttacaccaa catttataat
    14521 tctatcagcc tcaccaacac catggaaagc tcctgccata aatggattat cttctactgc
    14581 attacaaaat actactaatt ttgcacaacc aaaacctttt gcatcttttg ttaattctgc
    14641 agtttctttt atgatttctc ccatttcttt cactgcatcc atatttatac cacatcttgt
    14701 agaacctaca tttactgaag cacatacttt attagtactt gctagagctt ttggaattga
    14761 cttaattagt atcttatcac cttttgtata tcccttttga actaatgctg agaatccacc
    14821 aataaaatct atacctaaat cctctgcagc cttatccaat gtctgtgcaa actttacata
    14881 gtcattttca tctgttgcac ctgcaataat ggaaattgga gttactgata cccttttatt
    14941 tacaattggg ataccaaatt cacgctctat atcttttcca accttcacca aatctttagc
    15001 agaactcata atcttattgt atattttttc tctagcttta tctccatcag ggtctataca
    15061 atctaataaa gaaatcccca tagttatagt tcttatatcc aactgttctt catctatcat
    15121 ctttattgtt tcaagtatat ttcctacatt cactattatc acctcccctt actgtctact
    15181 acagattatg cattgaatta aatatttctt ctcgctgaat ttttacatcc actgataatt
    15241 tcttacctct ttcaaccaag tcctcaaccg ttttctcaaa agaatttaat gatttctcta
    15301 aatcaactat cataatcata gtaaaataat cctgtaatat tttttgtgat atatctacta
    15361 tgttgatatt ttgcttgtat aattcatcac taattcctgc cactatacct ggtttatcct
    15421 ttccaattac tgttaaaatt gctttcataa taatatcctc ccttattttt ttataaatct
    15481 tatattttta caaattgaac tatgttttaa catatatttc atttatttgt tagtaaacca
    15541 ctttttatgt atatatttaa tatattttaa tacctataca ttcatttgtc aatttttttt
    15601 caatattcta ttatttttat actatttaga aaattcatat attatatatg ttttctcaac
    15661 aataaataca gttttcataa taatgaaagg tattacttag caatcgcatg attttctaaa
    15721 taataccttt ctaaaaatta tttttttaat tttatgaatt taattatact ttttctagta
    15781 tcaggattta caattaatat agaaccaatc ataattggtg ttagtataca aaataaaaaa
    15841 ataatatctt tttttagatt atattcttta gattctaatt tataattatt atttattatt
    15901 ccatcataat cacttatatt tgacttattt ttatttgtat cttgattttt gttagaaata
    15961 ctttccctat aaggaaaaga atgttcattg gtaccaaata ctaattttga gcttaaatca
    16021 taattatcat cattttctgt aattgaattt ttattgtaaa atcctttttc tttatcagaa
    16081 ttattttctt tattaccgtc tttaggtata tcatgaggat ttttattttc attgctatca
    16141 gtacttgatt ctacatcatc tttaggagta tttggttgtt tctcatcaga attatcattt
    16201 tcattattat tattttcatt attattgttt tgattgttat tactatcatt attttcattt
    16261 ccattattcc catcttgatt gttatcatcc tcatctctat ccgggtcgtc tctacctcct
    16321 cctccacggt caccatcaat atcatcattt tcccgttcat catctggtgt ctcttggttg
    16381 tctccgcctc ccattataaa tcctggttta aaaactatat ttgaataccc ttcttttaat
    16441 cctcctacca cttttactct aaaacaacgc aacttaaaat cttcaaaaaa aagtatagct
    16501 tgatctctaa tatcctcctg ttcttcagat atccaattga ttccatcgct tgaatattca
    16561 acaaaaacct tacttgcact atacggcata tcataaaata aaacagctac atatccattt
    16621 tttgtatttt gaaattccag ttccaaattg tctattggtt ttttctctat aacagataca
    16681 ttcaaaatag gaactacatc atcatttatt ataatttttt ctttatttaa catttctgtt
    16741 ttaaactttc ctgttatatt aaaattttct cccttttcca acttttcata ataatcagta
    16801 aaatcccatt ctacatctat atcaagtcga ttaccactag atgtttctaa taccatatat
    16861 ttgggaaatt ttatattttc tattttatca tctttactta cttttatttc atcactaaat
    16921 acaccaattc ccctatgaca acatttcaca atatcatagc cagaatcttc agctatagag
    16981 ggtataagct cattataatc atcaattata taaactttct tactttctga tataattgat
    17041 tgtgccaact tattattatc ttttagtaac ccactttcat tgttgctact atatgctttt
    17101 attgaagttt cttctatctc aacatcacct ttagaataaa cacctatagc atgttctcca
    17161 ttcacttcaa tatccttatt tagtattcta atatcatttt cagtataaat tcctattgca
    17221 tctttcccat ttgcctttat tttttcaaca gattcgtagg atgatttaat atgtaagtct
    17281 cctccttctt caacgtataa ggctgtccca tcagtagcaa ttatgttgtt tataccaata
    17341 cttatacttc caccattttc tatatgtatt actccttctt ttcctccttc acctattata
    17401 ttcaattcat tatcatcaat aataaatctc ccatgatttt ttatcaatat tttatatttg
    17461 ttggtatcta ttgtaaaatt actgtcataa ggaatataaa atctaaactc ttcatctatt
    17521 accatatcac aagaaagagt ataaactatt tcttctttat tatttttatt ttcttgaacc
    17581 cacctttcaa aatcttcaag acaattttcc tcttgtccaa aaactttatg tggaaaactt
    17641 ataaaacaca aaactattat actcataaaa ataaatatct catacttttt catcttacac
    17701 tcctagaaat tttttagctt tgaaacaatc tgtcgaaaca tacacttcac ccactataat
    17761 ttttccacaa ttatcaatta ttgtcaattt ataaaagtat ctttattaat tgttataaat
    17821 aaaaagctac ttactaaagt aaacagacgt ttcactttaa taagtagcta tatttttata
    17881 acaaaatagt tataatatta gaacttcctt catttacaat tttttgtaaa gtcttttgca
    17941 ttttaactct tatctcttct ggcatagtat ataatttact ttgtaattgc tcttttacta
    18001 agtcatgtag tgatttacca aacatatttg attcccataa atctgctggt tgctcttcaa
    18061 atacttccat aagatatttt atcatctctt caccttgatt ttgatttcca actattggag
    18121 aaacctctgt agatatatct gcttttataa tatgaagtga tggtgcattg gcttttaact
    18181 tgataccata ttgttttcct tgtttcatta tttctggttc ttccagacta agttcttcta
    18241 aggaaggagc tactactcca tatcctttta tcttggcatc tattaaagca ctttctattt
    18301 tatcatactc atttttaact ttagatagtc tagttatcag actaagcagt tgataatctc
    18361 cttcaatttt aaatccactt ttttcttcaa ggacattata gaataaatct tgctttgtct
    18421 gtaaatcaat atttataaca ccttctccta gctctacatt atcaacacct gtatcttcca
    18481 aaaactctaa ctcagaaaat ccttgtataa taccttctat atcccttatt ttacctatat
    18541 ctataatact ttgttttaat gttgttatta tgctactttt tatccaatga tttctttcaa
    18601 gaccttcaac ccattttggt aagttgattc ttatttctgt aagtggaaaa tcatataata
    18661 cagcttccat aacctcctct atatcttctt cttccatttc aaccacattc attggaagaa
    18721 ctggaacttc atacttttct tccaattcac ttctaagcat actcgtttcc tcactttttg
    18781 gacttaacgt atttaaaacc actgcaaatg gttttttaag atttttcaat tcttgtataa
    18841 ctctctcttc tggttctaca tagctttttc tgtcaattcc agtaactgaa ccatctgtca
    18901 agacaactat ccctattgta gaatggtctt ttataacttt tttagttcct atctctgctg
    18961 ccttttcaaa tgtcatagct tcttgtgacc aaggagtgga tactaatctt tgttttccac
    19021 cttcctcatg ccctaaagct ccttcaacta tgtatccaac acaatctacc attcttactt
    19081 ttaaagatac tgtgtctttt atttttattt ctacaccatc tgctggtaca aattttggtt
    19141 ctactgtcat tatcgtttta cctgaaccac tttggggtat ctcatctctt gttctatcct
    19201 ttttaaattc attgtctata ttaggtataa ccaacttttc cataaatttt cttataaaag
    19261 ttgattttcc tgttcttaca ggtccaacta ctccaatata tatatccccc tgagtccttt
    19321 tggatatatc ttcgtatatg ttattattca tattattcct cctatacatc taatcttatt
    19381 aaattatatt tagagttaag ggttaatatt cttaaaatag aaaaataaag accagcaata
    19441 ttaatttaat ttatatatag aaatttgtaa atttcaatgt aaattaaatt aatattgctg
    19501 gtccaaatag tagtgtatta tattaactga ctttagtagt attttcattt gaattattat
    19561 tcatctcaat aagttcttta catctttctt ttgtcatgtt catccatata aatgtaaaca
    19621 ccaatccaat tatggctact atagtaagaa ctatgaagta gtacctatat ccagttacac
    19681 ccggaaatgc atccaatatc ttccctgctg ctaaaggaca aagtacttct ggaagatatc
    19741 ctaacgtagc aactattcct atagcagttc ctgatattga taatgaataa ttaccttctt
    19801 caagtaacga atagtgtaaa ccttgaattg catacataga tacatatatt gcaacacatc
    19861 caatcaatag tatataaatc atagatgatt ttgttggtgt aaatattaca cctaaaagac
    19921 ctgcaatcat aagtataaat ccataagata taatctttga tgaaccaact ttatctccaa
    19981 gtaatccaga agcagctgat gctactggtc tacaatactg agctaatatt gagattgcag
    20041 atgcaaacac cacagtagct ccaaatgctt cagttgaata aggcgtaaaa taataaaatg
    20101 acatattagc tgaatatgaa caaaacatta ttattgttat tatccatgta tgaggcattt
    20161 ttattactgc aaaaaaggct tctttatcaa attttgctga tacctctttt tcattatcct
    20221 ttaatttgaa aaatactaat actccaacta ttacatttat tgctgagtat aatactataa
    20281 tagctgtaag accagattca tcacttactt ttgatgaaat atacccaaat agtatcaata
    20341 ctagagatag atgaattgca ttggtaattc cacgaccact ttccataaat ccaaaagctt
    20401 ttccttgttc attttcagat gctaacattc taacagcttt tacaagagct ggccaaaaag
    20461 taagtattgt tgttattccc cataaggcat ggattaaaaa cacaacaata tatggaggat
    20521 aaagtgttaa tacaagacca gatattcctg taataattaa agaacctgaa agcaattttc
    20581 tggctgaaat acggtctgct aaaaaaccac caaaaaggta tgataccatt gcaagtagac
    20641 cataaatgct tcctaagctt cccatttgtg tatttgtaag attaaatgct tgtgcaaaag
    20701 tatcataata ataattcttt aaatatggta aagcatatat aaatgctcct gctacaaaga
    20761 gtattatcaa gactttgaaa tttttccaaa tgcttggttt atttacttca actgacatac
    20821 ttcctcctta tgtaaatacc tgtaaatttt cataataatt aattattgct tattttattg
    20881 tttattcaat atttaggaat atttattaat atattaggtt aatctatcaa taatttatgg
    20941 tgagttatga gctaaaagta aactctttta gctcaccata ataattatat ttttatttat
    21001 actaacatcc agagttatta gatatctttt tttcatagtt cttccatagc attaaacctg
    21061 ttattataac aaaaagacct cctcctatca tttcaatctc atagattata ttatctttta
    21121 aagtctccat aactggtgcc gttgagaaaa gtatgccaac tacagttact acaagtacca
    21181 ttctggcaat attgatacaa actgaatcac tttttgcaat tgaatatggt ctttcttcat
    21241 ttggtcttgt ctttctaagt ctaatataag atgtaaaaag caagacatat ggaaataatg
    21301 ctgttaatgc tgtcatagta acaagaacat tgtatatatt atctactgat ggtaataagt
    21361 ttgttcctac aagaagtaga ctcactatta tagcctgaac tattactgca tttgatggta
    21421 tattgtattt atttgtaaca gtcaattgct taggaaatac accttctctt acatttccaa
    21481 aaagcatctt tactggacct gctatataaa gtattaatgc tcctagtact gataaagtta
    21541 ttccaaatgc tactattctt ataaaccaac ttcctatacc taaatcttgt gcaactttag
    21601 ctaatgcatc tagtatccct gtagatgctg caattttatc tggaggaagt atcattgtta
    21661 ttgctactga acctaagata tagattcctc ctattaaaac agccacagtt aatatagctt
    21721 taggaaagtt tttcttagca ttatccattt cggttatgaa attagcagtc gtttcagctc
    21781 ctgataatgc aaatattata gcagatatag aaactaatga attggcatct atttttggta
    21841 ttatattttg gattgtatat atcgatgctg atggagcttt tttgagaata actacagaca
    21901 taaatgccat cactataagt aatatagcag gaattgtaga acctaatgct cctgtattcg
    21961 taaaaaattt tccaaatgcc atcccacgag tacttactaa ggacaacagc caaaatatta
    22021 tgagtgaaag tgctaaaata aacatcttat tgtttgataa atctggattt ccaagcatat
    22081 atgcaatatt tatcgctaaa aaagtcaaga aagaagaata ccaaaatatc tttgatgtcc
    22141 aatttagcca tgacaccata aatccccact tctctccata agcttgttta acccattctc
    22201 caagtccacc atcttttgga tatgttgcag ccaactctgc acatataagt gatgcaggaa
    22261 caaagaatat aaaagcaaac aataaccaaa ctggtataga accaagaccc aatccaaaac
    22321 tagaggcagt agatttagct atccatctaa tcccaaatag tgctgatata ttcataaata
    22381 ctaaatccca aaatccaatt ttctttttca ctgtaattcc tccaatttca aatttattca
    22441 gactcataca caatgtattg acttaaatat caagtataag ttcttcaaca cttcttggat
    22501 aattagttat aattgtagca ccattcttac ctactattgc tgtatctgag tgtctaaatc
    22561 ctccaactcc aggtatatat atccctggct ccatagaaaa taccattcct tcttctaata
    22621 ttaattcatt gtcaaatctt aaatatggct cttcatgttc tgataaacct aaaccatgac
    22681 caattctatg atttgaatat aactctagac catactttgc aacaacagct cttgctgctt
    22741 catccaccat tcttgctggt ataccagctt ttattgtatc taatccagct tgttgagcct
    22801 ctactgcaat cttaaacact tctttttgtc tttctgttgg tttgcctata ataaaagttc
    22861 tttcattttc tgctctatag ttttcatacc aaacctgtct actatgtatt actatatctc
    22921 ctctttgaag tattctagta ttggaatcta aatgaggttg tgctgttcta tcaatccctg
    22981 aacaagtcca gtttgcaaat cctatatatg tatcaggata attttcagaa acatatttta
    23041 gtaaagcatt atcccctgca acgtcaaact ccaattcact catcccaact ctaacatttt
    23101 ctaaagaccc ttttattcct atatcagata ggtaacctgc tatcttcaaa aattctattt
    23161 cttttgcatc ttttacatat ctcatttcaa atattttact tccaacatct ttgatagcaa
    23221 atgacttatc agttatatac tctgaaaagc ttgcagatac tatatctttt tctattccaa
    23281 cagttgttcc tttagggtat ttatttaaaa ttatatctaa gtaatgttta tgtgatattc
    23341 catgttcttt catttctggt atttcataat acacatatac attatcaact tttgcaactt
    23401 ctttagcatg taattcttct aatccaggta ctattaattc tattttatct tgagttacta
    23461 ctgttacaat tggtctagaa taagttattg ctttaaatcc actaatataa aattgattgt
    23521 ctggttcaaa tattaaagca atttcaatgc ttttttcatt catgtacttt ctcaatcttt
    23581 ctagtctcat attatttgac ataatgcacc tctttcttaa tattcagata atttattcaa
    23641 tacaacaagg atgaatatat tattttaaaa ttcttaatat ttttagtact tgtcgtattt
    23701 gtatgtaaat taattttatt tgtgattatt ttatcataat catgattatt ttgtcaatca
    23761 tgattttatt ttaaaaaatt ttttatattc tagtgatttt aaattatcta aaatataacg
    23821 agtatacatt gtattttgta atattattct tgatttatgg taagtttaat gataaaatca
    23881 cgattatata aactatattg attatttgta ggtgaataaa atgacaaata aagaattaca
    23941 aaagaaaagg atattgatgt atttcataga agctgctcaa aatattatgg aaaacgaagg
    24001 tatagaaaat attacacttc gtaaggttgc agatatggct ggctataata gttcaactct
    24061 atataaatac tttaaaaatt tagaccattt aatatcattt gcatctataa aatattttaa
    24121 agattataac ttgaatattt caagatgtat agaaaatgtc aatgatgaat ataagaaata
    24181 tataattatg tggaaattat tttgtaagca ttcttttgat aatgctcaag ctttttacca
    24241 ggtatttttt aacttgtcta gtgatgaact tagctatata acaaaacaat attatgatat
    24301 gtttccagaa gatttaggta ttcatgatag tgacatatct ttaatgatta caggagaaag
    24361 tataaaggaa agaaataaga tactattaaa caatcttgta gatactggat atataccagc
    24421 taaagattta gacataatca atgatataat tatttctttt tatcaaaatc tattattctt
    24481 aaaaaagaac acaggaaaaa attctgatga tgatgaatta actatgaaaa tgatttcttc
    24541 tattgaatac ataataaaac atgctaaata aaattaaaat atggctgtct caaaatagag
    24601 ataagccttt tttattgttg aaataataaa aatatattta atttcatata aaaaagagtg
    24661 cctcgtaaac taaaaagttc attttgagac acccctaaaa taaatttatt atttattata
    24721 caatagttta tatatcatca cctaaaacta cttcttccat ttcatgcttt ttacttctca
    24781 tcattagttc tattccaact tctttaggat ttgaaccttt ctttattaca gaatatatag
    24841 cattagttat aggcatatct atatctaatt tttcagcaac atcatgtgct acttcagtag
    24901 cagttatgcc ttctacaacc atctttactt cttttaaagt atcttctaaa ctcatccctt
    24961 tacctatgag tataccagct cttctatttc tactatgcat acttgtacaa gtaactatta
    25021 aatctccaat acctgaaaga cctgcaaagg tagacatatt agctcccata gcaattccaa
    25081 gtctgctcat ttcactaata cctcttgtca taagggcagc ttttgcatta tcaccatacc
    25141 ctaatccgtc acatatccca gctccaaatg ctataatatt ttttaatgct cctccaagtt
    25201 ctactccaac tatgtctgga ttcgtataaa ctctaagttt agggctcata aataaatctt
    25261 gtatcatctg tgctattttt aaatctttag aagcaactac tacggtagta ggaatatccc
    25321 ttgctacttc ttcagcatga gatggcccag atagtattac atatggattt tgtggtaatt
    25381 cttcttcaca gacttgagat aatctaagcc cagtcccttt ttcaagacct ttagctacat
    25441 taacaataac ttgtccttct tttataaatg gttttatttt ttggcaagta cttcttacag
    25501 cctgtgatgg aactgctaaa actattacct tacaatcttt tatagttttt tctatatcag
    25561 tacttatagt tatattattt ggaaataata ctcctggtaa atagtctgta ttttctttag
    25621 ttctgtttat ttttttagct tgttcctctt ttcgagtcca catgctcaca tcattacctt
    25681 tttttgcaag ccctaaagct aatgcacttc cccagcttcc agtacctaat acacatactt
    25741 tctccatgtt taacaccacc tgagtataat atatttacta ttctttcttt tgaccaattt
    25801 ttctctctgt cccatttaat aatcgcttta tatttgctct gtgattatat attactgatg
    25861 cagttaagaa cagagctact attaaaccag ctttattttt taccataatc ataaatattg
    25921 gtgaacatcc tattcctaca acagaaccca atgaaacata ctttgttata gctaccacca
    25981 atataaatac tgctagacac attagtgtta ttactggatt tacagctagc attgccccta
    26041 gtgaagttgc aacacctttg cctcctctaa atcctaaaac cgctggccaa ttatgacctg
    26101 ctacaacaca tataactgcc agatatccag ctaaaagagt atctattcca accaatcttg
    26161 ctgcaaattc tgatattaaa acagccatta cacctttaag aacatcacct aaaaatgtca
    26221 ttgctcctgc tctttttcca agtgtcctaa gtacatttgt cgaacctgca ttaccagaac
    26281 cttgagtcct tatatcaacc ccagcaattc gctttgcaac tatgtatgag gtagatatat
    26341 ttcctaaaag atatgcaact acagcaataa ttatataact aaatatctcc actgaatttc
    26401 ccccctttag ttatatttta agatatttat tttttatttt tttgtctata ctcaaacttt
    26461 atggaagttc cttcaaatcc aaaattttct cttatcttat tctcaaggta tctttgatat
    26521 gagaagtgag ttaaatcctt atcatttata aacaatgtaa ttttaggagg tctaatgtca
    26581 gtttgagtcc catagtaaat ttttaatctt ctacctttgt cagatggtgg ttgatttaac
    26641 attacagctt ctccaattac ttcattcagt gctgaagttg atattctctt agaatgttca
    26701 tttgacacat attcaactgt atctagtatc ttgttcattc tttgattagt ttttgcagaa
    26761 acaaatacga ttggagcata catcataaat ggaaattttt cttttatatc ttttgtgtaa
    26821 ttgctcatag tcttattatc tttctctatt aaatcccatt tattgattac aaatatgcat
    26881 ccttttcctt catcatgtgc tatacctgca acctttgtat cttgttctgt tacaccttct
    26941 aaggcatcta ttactatcaa tactacatct gctctatcta cagcactcat agcccttatt
    27001 acactgtatt tttctattgt ctcatatatt ttactttttc ttctaagccc tgctgtatct
    27061 attagaagaa atttctgtcc atttttttca aaataagtat caattgcgtc tctagtagtt
    27121 cctgcaattg gacttacaat tactctttct tctccaagta tcttattgag tatagaactt
    27181 tttcctgcat ttggtttacc tgttatagct actcttatta tatcttcttc atactctgta
    27241 tctaatcctg ctggaaaatt ttcaactatc tcatctaata aatctccaaa tcccatacta
    27301 ttggctcctg aaactgcaaa aggcgttcca aatcccaact cataaaaatc gtatatatta
    27361 tcaaattgac tttgactatc aatcttatta accactaaga ttactggttt ttttgtcttt
    27421 ctaagcaatt gtgcaatttc tttatcagca gctgttattc cagctttacc atcaactata
    27481 aaaagtatta catgtgacat gtccattgca agcatggctt gatttctcat ttgagataat
    27541 attatatctt cgctatcagg ttcaattcct cctgtatcca ctaatgtaaa atatttatct
    27601 aaccattcta cttcagcaaa tattctatct cttgtaactc caggtgtatt ttcaactatt
    27661 gatatccttt ttcctgcaaa tttattaaat attgtagact taccaacgtt tggtctccca
    27721 actacagcta caactggcct acttatactc attttatttc tccttccatc ttttgttttc
    27781 tattttaaaa ttttatccac aaaatctttt ccttcattca aacaagggat aatttttatt
    27841 ctcataagtt cttctaattg atttaattca atattatcta agaaaatttc ttcatctgct
    27901 tttagcatac ttcttgttat ataaagagct tctcctaatt ctttatcttc aagttgttct
    27961 tttaaatcct tagctgttaa aagacctgat acagttattg tctctccaaa aaacttgttt
    28021 ttgatttcat atacatttac ttgaagattt ttaaacttgt ccatcatagc atctgccata
    28081 ctctgtataa attcatatgc agaatgacca gtagctattg atactttctt ctctcttttt
    28141 agaatcttct caggcaatat atttagatac tcttcaatct ctgtttttaa cttacgtatc
    28201 atacctacac catcttcaaa ctgtaaaaaa ccttcatatt cttcatatcc aggcaattca
    28261 ctattagata gtatataaaa ttcatctgat aaaaatgcaa atcgagtacc taatttttca
    28321 agatatttct gttgtatttg atgtatttgc tctatagttt tacttgcgct cttatcatta
    28381 aatatattta attctactag attttctcta tgctttgtaa tcccaactgg aactatcgca
    28441 acactgttta catacggata aagttgagct agttctttta ttgttctatc caattccttt
    28501 ccatcattta tacctggaca taaaacaatt tgacagttca tttctatatg agcatctgcc
    28561 aatctcttca ttataccata taattttcct gcaaatttat tgcttatcat tttttgtctt
    28621 aactctggat tagttgtatg cacagatata tttataggac ttattctata ttttataata
    28681 ttatttatat cttcttcact catatttgta agtgtgacaa aatttccttg taaaaaagat
    28741 aatctcgaat catcatcttt aaaataaaga gtttctctca taccttctgg caattggtct
    28801 ataaaacaaa acatacactt atttctacag cttttagctt ggtcaattat cggatttgta
    28861 aattcaacac ccaaatcttc atcatagtct ttttctatct cgtatatgta gacttcgcca
    28921 tctttttttt gtatttctac atctaaatat tcatcactta gtaagaatct atactctatt
    28981 atatcatgta ttggctgttc attcacagat ataagtaaat ctcctacctc tatacccatt
    29041 tcttctgcaa tactatcttt ataaacctta cttataatat tatttacttt ttttacattt
    29101 acttccaata ttttcaccac tcttttgtat tcatcaatgc ttattataat gtattttaat
    29161 atgcaattta tttatttatt atattttatg atagcatttt taagcatttc atgtcataat
    29221 aacacatttt aattctaata gtcaatataa gtaaatagct ataaaataga ttagaacaaa
    29281 taatattcaa atttaagttt cttaaaaatt taaatattat ttgttcttaa aaaaatttta
    29341 taaatttaat gttttactat gattaacgtc ccatttgtca tatcatgaac cattccacct
    29401 acacactttg acatcaacaa tgccttattt tgtaagtctt tctcatcatt tgcataaaat
    29461 attggacaac ctccaccatt tttcatattc ttatcaagtg taactatagc tagggtatat
    29521 tcatttaaac ctatatccat tcccatctca tgcacttcct ttctttccta ttttataatt
    29581 ttttagtgat aagttttttc ctttagagct tgaaagtatt gggcatgact ttacagcttc
    29641 cattactttt tccacattct tatctactgg taaataagca atcattatac tttcatcctc
    29701 tttatttctt ctaggtaatg gtacgaatga aggttctcca taatctccat ataaacctaa
    29761 ccttgaatat atattgtata ctattgcttg tctttgaccg gagtcaaata atattcctgc
    29821 attagcataa tccttatttt taggaattat ttgtattcct acacctctat taatatatac
    29881 ttctctatcg ctttttagac ctatatttgt tatacctttt aaatctccca cctttagtat
    29941 agattcgtcc acaaaactaa tttcagcagg cattacatca gctatgtctc caatactttt
    30001 tctagtaaga agttttttta atataaaggc taacactaat ccacaaattg aacttattac
    30061 caaactcatc ccttcactta ttttcgtttc tgcaagtatt acataataca atcctattgt
    30121 taaaaaagat gtaactatac acatataatt tcttacttca taggttctag ctatctcttc
    30181 tatgaatgca gctcctctct ttacaagttg aacttcctct aaattttgca atgtatttct
    30241 tctatttgct ctcacttgtc taaattgttc tgctgctaga gataaaaaag ttatagatgt
    30301 ataagaacga tttataagag ctggaaccaa taatgctcct aatgaagaag cgacgaatgc
    30361 taatataagt tgagatagta aaacatttgg ttgcgttgga tactgttttt ggtctaaatt
    30421 caacattata attctagatg ttataccaat aataacagca acaaaaaata ctctatccat
    30481 taaatcactc ctaaaatatt taatttgaaa ttttacatgt aaatctacaa agtctttcta
    30541 gaaaaatcac tctgctttcc ttttgatgtt tctatgatag gtgtactttt cactacatct
    30601 atcatgacat ctatatcttt gagtattggc atatatggta taaccacagt acttttttct
    30661 aaattggtct tagatatagc aacaatatca acctcatcta catctctatc tatccccata
    30721 tgaataaata gattatgtat tatagcttgt ctttgcccta tatcatttac tattccaaat
    30781 gcacctaaat ctcttggtat aacttctatg gccagacatt catttctata cttttctctt
    30841 gtactttcta gacctatgtt agttattatt acaccattta ccattaaaat aggtccttca
    30901 aaacttattt ttgcaggaac tatatctgct atatctgcta tactgttcct tcttaaaaat
    30961 cttctaaaaa tcaaaccaac aatagctcct gacacaatag ctaggattgt gcaataaaaa
    31021 aagctaaggc catactttct tgcaaaaacg atataaacta tcgaagatac cagtgcagaa
    31081 aaaagactta tataacttct agattcatac gtagatgcta tttcttcaac gtaagcgtct
    31141 ccttttggta ctaattcttc attatcgata ttctttagtg ttattctttc ttgttctgca
    31201 agaccttgaa actgttgtat tgctactgca aaaaatgtca aggctgcaaa ctccttatct
    31261 ataagtgcag gtaatgctat agcacctaac gaagctgaaa gcccagatat aattatctgt
    31321 tctaaataat cttgtggtct tgatgggtat tgtttgtctg taactcttaa aactaatcct
    31381 ctacataata ttcctacaac taatgcaact ataaaagagt gtctaaataa atttgcattc
    31441 aataaacttt cttccatttt ctcagctcct tctcttatat agtttgtgca aaaaacaaaa
    31501 aaaattccct tctatttaag gaaatttttt tgtaatattg taactataaa ttcgctacca
    31561 atgccaagtt cactttttac ttttatacat ccatttagtg atttgactat atgctttgtt
    31621 atagccaatc ctaaacccgt tcctcctaca tccctacttc ttgctttatc taccctataa
    31681 aatcgttcaa atatgcgttc tacatcttct tttggtatcc ctacaccatt gtctataact
    31741 ttaattacga ttttttcttc atcttttaac actacaactt gtacaatccc attatcttgg
    31801 gtatacttta tagcattatc aactaggttt aagaacactt gctttatata gtctttattg
    31861 gatagtatac ttattgattt atcatcacat ttatataaaa cttctatatt tttttcacta
    31921 gctgaatgtt gagttatttc atatacctct ttaaatacat catatactac aacattttcc
    31981 ataagaagag tatctttatt ttctacaaat gataacagca atatatcatc aatcaacctt
    32041 tttaatctat ctgattcgct ttctattatt tctaagaatc tatttctagt attcacatct
    32101 atattttcat ttgactttag tgtttcaaca aacccactta tagatgtaag tggtgtttta
    32161 agttcatgac ttacatttgc aacaaaatca cttctcatat tttcaagttt aactttttta
    32221 gtaatatctt ctatatttac tatcgaacct attattacgt tgttagtatt ctgaagataa
    32281 actgggtcta cttttatctt atatacgata tcatctttag tagtaatatt agcagtttca
    32341 ttatctttag aaccaataaa ttgaagtatt tgttttaata tttcttcttc ttttattaca
    32401 acattaatat tatgaccttc aactaattga tttggttcac tctttatcat ttcttttgct
    32461 tcatcattta tcagaagtat atttccattt acatctatag ccaaaattcc atgagatata
    32521 ctctttaata tagaccttaa ctgtaaatgt ttatactgta cttcttctaa ggttttatcc
    32581 atattcttta tcatatgatt aaaatttcta gctaattcgc caagttctcc tttggctgat
    32641 atgttaagcc tagcatgata ttcattatta cttacttttt ttgagacgta tataaactct
    32701 tttaaatatt tccttaatgt tattgtgtat cttacagcta atataacaat ggctatggac
    32761 aacataacaa taaaaaaata tatactattt aaatcttcca caagataaca ctcctaaaat
    32821 ataacctttt taatctattt tgtatcctac acctcttata gtctctatat atttttccga
    32881 tttatcttca tcttctattt tttttcttaa atatcttata tgaacatcta ctgttctagt
    32941 ttctccatag tattcatacc cccatatttt atccaaaaga taatttcttg aaagtacttt
    33001 tcctttattt tgaattaata attttaacaa ttcaaattcc ttaagagtta actctatctt
    33061 ttcagagcct ttggtaactt catgttttga taaatctagt tttaaattac ctgtagtaag
    33121 tatattgttt tcttcaccta agctagtcaa attatatctc cttaaaacag aactaatcct
    33181 agctaacaac tcttttatac taaatggctt agttatatag tcatcagcac ctatttcaag
    33241 cccttcaacc ttgtcatttt ccatattttt agcagtaagc attataacag gaatattttt
    33301 taagtcctta tcacttctta tttttctcaa aacttctatt ccacttatat ttggtaacat
    33361 ccaatctaaa agtattaaat ctggtttaat ttccttagcc tttataaatc cgtcaaatcc
    33421 atcatatgaa taactaactt cgtaatttga cacctccaaa ttgaatttta atagctcaac
    33481 tatatgcatt tcatcgtcta taacaagcac tttagtattc attaaaaagc tcctctctat
    33541 tttatctgta gtaccgttcc tattcgttct gatgccttat tatgttttct ataagagtgg
    33601 aatttatctg ctctacaact agtgcataaa tttaaattta ttatattttc ttttttaact
    33661 ccactacatc taagcatata ctcattaatt ttccataaat ctaaatagta acttccctct
    33721 tttattatat agaacttttc atcattattt gtaagaattg tgttaaattt ttctactaaa
    33781 tcttcagaca cttcataaca acatggtcca attgatggcc caattataca tactaaatct
    33841 tcaggaactg ttttatagca ttcagacatt aattttattg ttttatgacc tatattacta
    33901 aaagtccctc tccaacctgc atgagccagt cctatggctt tatttttagc atctataatt
    33961 gatataggta cacagtctgc tgtaaacagt aaaagtggta ctttttccaa gtttgttata
    34021 agtgcatctc catctcttct tttccctata gtatctttat tgactatatt aactatatct
    34081 gaatgtattt gagaattact agttagattt tcaaatgtca aatcacattc tttacatact
    34141 tttaacatat cttctctatt ttttgcatct atattcttac atgttataac tagatttaca
    34201 gaatttaatt tttcatcaag ttcttcacaa ttaccactta aattaacata ctctttaata
    34261 tcttgtacat tttttatatt tatataatct ttcatcattt gtctcctttt tctatcagta
    34321 tacttttaag ttcatttaca aaagtattta tatctttaaa ttgtctatac acagaagcaa
    34381 atcttacata ggcaacctca tctaactctt tcaatttatc cattaccatc tcaccgattt
    34441 ttttggtttc aatttcttct ataaaacatt tatttatttc attttcaata tgtacaacaa
    34501 tactttcaat ctcgtcaata gaaacaggtc ttttttcaca tgcttttagc aatccatatt
    34561 ttatcttttc tctatcaaaa tattctctac tattatcctt tttaatgacc attaaaggag
    34621 ttgtttctat tttctcatac gtagtaaacc tctttttaca tgattcacac tcacgtcttc
    34681 ttctgataga ttttaaatct gtatgtctag aatctattac ctttgattct ttataattac
    34741 aataaggaca ttgcatctat attcctcctt tgtttaacta tatctcaaac tcatctaagc
    34801 ttaattctga acctatattt actattattg tatcacaacc tattttaagt atatcattcc
    34861 aaaatataac ttcttcatcc cctcctcttg aaaaaaaact tctacttcca tctccaaaaa
    34921 tggtaaatga gactacctta ccttcgtgaa tatccatgtc tatgtctatt ataaacccca
    34981 tcctttttcc attttttaca tttataattt ctttttccat tatatcagaa actctaatca
    35041 tattgtactc accctttctt taaaaataaa tatgtatcga agtaaaaaaa aatgacctat
    35101 ataggtcatt taaattaaaa taatgtttac agtccatgga ttacttatac atattttctc
    35161 atatttttta aagcattttt ttcaattctt gatacttgtg cttgagatat accgatttca
    35221 tcagcaactt ctatctgagt tcttcctttg taaaacctta aatctaatac caacttttct
    35281 ctactattta atttcttaat agcttcttta agtgatattt cttgcaacca attttcatca
    35341 gtatcttttt tatcttgaac ctgatccata acgaatattg catctccatt gtcttgatat
    35401 actgggtcaa acagagatat tgggtcttgt atggcatcaa gtgccattac aactgattct
    35461 acttctaatt ctaattcctt tgctatttct gatactgtag gttctttaga atttgttcta
    35521 attaatcttt ctctaacttg tagtgcctta tatgctatat cttttaatga cctacttact
    35581 ctaattgggt tattgtctct tagatacctt ctaatttctc ctataatcat aggaacagca
    35641 taagttgaaa accttacatt ttggcttaaa tcaaagttat ctatagcttt tataagacca
    35701 atacaaccta tttgaaataa atcgtctata ttttctcctc tgttgttaaa cttttttatt
    35761 acactcaaga ctaatcttaa attccctctt acaaactgtt gtctggcttc ttcatcacca
    35821 ttttttattt gtaataaaag ttccttcatt tgcttatttt taagaactgg aagttctgat
    35881 gtattaacac cacatatttc aaccttatta acttgcatat attttcagtc ctctctcaaa
    35941 agtattcatc tattgaaatt atttacattt ccaatttttt tatacttttt aagaagaatt
    36001 aatttagcat tatacaaatt ttttcatttc tttttgcaac cttgagatta ttttcttttc
    36061 aagtctagat atgtaggact gtgatattcc aagcattcca gcaacttctt tttgtgtttt
    36121 ttcaatacct ttatcaataa gaccaaatct taattccata atttgctttt ctctgtcact
    36181 taatctgtca agtgccataa ccaacaaatc tctatctatt tcttcttcaa ttattttgta
    36241 tatttcatca ttttctgtac ccaatacatc agataataaa agttcgtttc catctaaatc
    36301 tatatttaaa ggttcatcaa atgatacttc tgttttcttt ttattatttt ttcttaagta
    36361 cattaatatt tcattttcta tacatctcga agcataagtt gccaatttta tatttttatt
    36421 cagtttaaaa gtattaactg cttttatcaa acctatagtt cctattgaaa tcaaatcttc
    36481 tacatctata cctgtatttt caaattttct cgatatgtag actactaatc taagatttct
    36541 ttctattaaa attgacttta cactttcatc tgtttctagc ttttgtaaaa gctccatttc
    36601 ttcttctggt ttcaatggag gaggaagtat atttgcccct cccatatagt atattccctt
    36661 tggctttatt atttttaatt taatacctaa catagtaata aagcttatta ttctttcttt
    36721 caatcgtaac attccttgtc ccccttaaat tttcacctaa aatccaggca atatatttgg
    36781 attcattatt gctccatatt ctctatcatt aaaatttgaa ataccaagta ttatatttcc
    36841 tatcttttgc tcatctactt ctatatagtc agcttttaag cctattatta tgcttgtctt
    36901 attacttcca gcatgtttat aaggtattat tctaactcta cctgaagttt tatcatctaa
    36961 acttcctata atttcttgtg ctttcttcat atctatatct tcataattaa tatttaatag
    37021 tttttctgga ataaatcctt ctaacacact agacttaact attattacat cactttgact
    37081 tattgggtct tttaacaaat taccactatc tactaaagcc ttacagcaaa aacttttttc
    37141 tagtaagttt atatttatag tctttgtaag ctccttaatg tacttaagca ttttcaaatc
    37201 tttataaatg tattttaata attcacaact cacataagta catgcaatta agaaagatat
    37261 ttttaagtga cttattcctg taaaataaat tataaaataa gtgcttccag aaataaaaat
    37321 gtttactaga taaaaaacta acgctacatg aacataatct tttttgctct tacttctaaa
    37381 tgaaattaaa gttattatac tcatgattat tattttaaat ggtacagtaa atagtatatt
    37441 cattgatgga tacaaataag caacagaata ggcacctcct aaactagccc ccaataactt
    37501 atttttttta ggattatatc ttttagtaag aatagaagta caacttataa taatataatt
    37561 tattactagg ttttctataa catagtactc aatatacacc atgtatcccc ccttaaaacc
    37621 tttaaacata ttataagata gtatgtacaa aattttatgt cacttttgat ggtcgaatcc
    37681 aaaacaaatt ctatttaaaa agaacaatga tatatgtctt atactttatg tcgtcaaaag
    37741 atattttttt aataccaaac aaatagactt ttttgtagaa tccaatatat ctaggtagaa
    37801 gttattcact ctacttttgg tatatttaca aaaaaagact acataattta ataatatatc
    37861 aagtaaatct tttacttata taaaatcaaa ttatatagtc tgtaaattca aatataaatt
    37921 attgtgctag taatccattt gcatattttg cagattcatt tagtgcttgt tctggagtta
    37981 tgtctccagc tatcatcatt tgaagttgtt tccataaata ttcatatatc tctactccat
    38041 gaggtccaac tgtcaatggt ctatacatat gtttatctct tgtcaccatt tcttcaaatc
    38101 ttgggtctcc ttggtatttt tcacctttag caactggagc tctaggtatt tctttgtgga
    38161 aagcttccat tgattctttg cttagcatat actcaagaag tttaaatcca agttctttat
    38221 ttttacatgc tgacattaat gttaaatcat ctactgaagc aaaacttcca actgtcttat
    38281 cttctaatga tgttacatat ccccagttta aatccgggaa tgatttatca aaagtacttg
    38341 tagcagcaga ggatagcatt atagtaaatg cagcttttcc tggtccaaat acactttcaa
    38401 tcatttcatt actatctttt gataaagcat cttctggaat atactttttc atatcattta
    38461 taaagtttgc agctttcaag ccttctgcat tattaaattt aactgatttt aaatcatcat
    38521 tatatatatc tccaccagct tgccataaat acggatacca gttccagttt aagcttccaa
    38581 atactttaga accccaacct tgtgcaagac cccactggtc gatttttcca tctccatcag
    38641 tatcttttgt tgctttttca cagattcttt taaaatcatc ccatgttttt ggaggttttt
    38701 ctcctaattt ttctagtata tctttattgt agtacaatac gcctggatta gcagcttcta
    38761 taggtaaacc ataaatacca cccatcattt ttgcatcatc taagtataga taattatctg
    38821 aagttcctga tttttctaaa taaggtgtta aatcttctac cgcacccatt tctataaatt
    38881 gaggaaacat ctctgcatac atgtatccta tatctggacc ttcacctgca cttattgctg
    38941 ttgcatattt ttctgcgtag ttatcccatg gtactatctg aaattcaatt tcacagttat
    39001 tttctttttc aaatttttca aatatcggct tccatgcatc tgcatcatgg tctgttaatg
    39061 gtgcagacca tacaactaat ttttctttac cctctttgcc tttagaatct tctttttttg
    39121 aacatcctgc aagaattgat actgatagaa tccctaccat aactaaagaa agaacctttt
    39181 ttagtttaat catgcttaat cccctttcag actttaattt gtctttttcc tcaaatgttt
    39241 acatttaatt cagatttaat attaacaaat aagattactc ttgtctaatc ataaaaaact
    39301 atactaactc ctataactat attttttttc tatacctatt agatttaatt catactaaaa
    39361 acttactttt taaattttat caatatttaa aaattttttt aagtctagcc acaaactaac
    39421 tatctaaatt gagcaaaata aaaagaagtc tattgacttc tttataagct tacatattat
    39481 cttcttcttc ttaggaatgt aggtatctcc atgctctcat catcatcttc ttcaattata
    39541 cttgcctttt taggaggctc tattttttcc tcagcaatta cttcttcttc aatttctttt
    39601 acagcttgtt ttactgttgt atttaatgaa gaacgtatgc ttgatttagg tttagtatct
    39661 aaatctaagg caccattttg taatccttca aatcctgtcg cgattactgt aatcattatt
    39721 tcatcaccta aatcttcttt tatagaagct ccaaatataa catttgcttc tgggtcacag
    39781 gattccataa ctaaagttga tgcctcatta acttcaaata atcctaagtt aggaccacct
    39841 gtaacattaa gaagtactcc tttagctcct tgtattgatg tttctagaag tggagattga
    39901 atagcttgtc ttgcagcatc aattgctcta gtttcaccac tagcactacc tatacccata
    39961 tgagcaagtc ccttgtcttt cattatagta gtaacatctg caaagtccaa gtttattaac
    40021 ccttcaactg ctataaggtc tgaaattgat tgtatacctt gttttaatac atcatctgca
    40081 actgcaaaag catctaacat tgatgtattt ttttgtacta tctgtaaaag tctatcattt
    40141 ggtatcgtta taagagtatc tacttttgat ttaagttctg ctattccacc ttcagcgttc
    40201 ttcattctta tcttaccttc aaatgcaaaa ggtttggtaa ctacacctac tgtaagtatc
    40261 cccatttctt ttgccaagcc tgcaaccact ggagcagctc ctgtaccagt accaccgccc
    40321 attccggctg ttacaaagac catatcagct ccttgaagta actttactat ttcatcttta
    40381 ctctcctcag cagctctttt ccctacttct ggatttgctc ctgctccaag tcctctagtt
    40441 aatttttctc ctatttgaac tttatattca gcttttgatg tatataaagc ttgtttatct
    40501 gtatttactg atataaattc aacgcctttt agttgagctt ctaccattct attgacagca
    40561 ttgtttccac cgccacctac acctattact ttaatttgtg cacattcttc taattctacg
    40621 tcaaagttta gcatcataaa cccccttctc tcatgattca aagttatcgt atgtattaat
    40681 tatatcattt tcttctttta ttttgttaac ctttaagtaa catattccac aaaaacgtaa
    40741 attttccttt ttaaatttct tacttatatt gtcaaatatt actctttaag tataaaataa
    40801 tttacgtata tattaaatgc tctttaattt ttacgttttt tgttcataat attactaata
    40861 atatatcgtc taattataga taagttatta aacaatctca taccaaaaac taatacagca
    40921 acatagtaaa gagaaactcc taacttttct cctatataag tcaataatat agccaatata
    40981 gcattaccta tgaaaccagt aataaaaatt acattatcat agttatcttc aaaattggat
    41041 tttatcgctc caaaaataga atccattatt gcaagaatag ctactgacat atatatggaa
    41101 taatccatag aatatgtaaa tggaatatag taacctacta ctacaccaaa tgctaatcct
    41161 cctaaaaccc ataacataaa tcttcacctc tttattttac tttgaaacac aactacatta
    41221 caatcctttt tattaatttt ttttactttt tctttatttt tttgtatttt tcgttttatt
    41281 ttgcaaataa atccacttta tttccattat tttcctgaac ttttatatta attccatata
    41341 tatccttaag agatttagca tatgattctg gagagtttat agctgcactc aataaatcta
    41401 tatctcctat agcttttatt ataaatggtt gtccatatgt agtatcattt actgtaatag
    41461 tagctcctga acattttatc ttacttgttg ctagtactct ttctccattt atagaaattg
    41521 ctcttgctcc agcctttttt aaatcattta aaaccctcaa aatatctata tcatgtataa
    41581 tcaaatcgtt tggattctgt ccgtctttta actctctctc actatccctc atagtaatag
    41641 ttatgcctgg ccctgtaaca gttgaataac cacttaattc tttaacttct tcaagctctt
    41701 tttgcataag tgtttggata gattcatttc cattcttttt tgcttcttta tattcattca
    41761 aagttttttt gttgttttta agagtttctt ttaaattttt tatttctttt tttgtatttt
    41821 ctacctcact ttcaatactt tcagtttgac ctaatgttat gtatactcta tttgggtcta
    41881 gtgattttat ataagttgat atgaaaacgc ctaatatgaa tgctcctaat ataactattt
    41941 tctttttcat actattattt cccctctgct ttgtttatat cactatgacc atttatttct
    42001 atattgtctt ctttggtcac ttttactttg gcattataat atgtttctat ttcccagaca
    42061 ataccatact ttatattaag tgccgaagcc aatgtatcag aatcaccaat tgcttttatt
    42121 ataattggtt cttttatgac agtgtcattc atataaagct tgtcttcttt taaatacata
    42181 tatgtattag aaactattct ctggtcgttt atagatatgg cacttgcttg tgctgagttt
    42241 aatttattta tcattgacaa taataaatca taattatata gtatactatc atttttatca
    42301 gagtttccta agtcttttgt agaatttatc tcaattttta tgcctgttcc ttcaacatct
    42361 gtatatccag ctaatgtttc atatttttct atttctgact taagtatgtc ttgttctcct
    42421 tcattgtttt tgcctctata agtctctata tctttcttca cactattaac ttctgattgt
    42481 agattctctt tttctttttt taaagattta agttcttctg taagttgctc tcctctttta
    42541 aaagttgtca tccctctatt ttctatatta ataattttaa gttgtaaact aacaagaaca
    42601 cccaatacaa tacttcctat gattatactt ttatttataa atcttttttt caatatatca
    42661 cttccttaca attgtctatc cttctggact atacactgcc aactttccat agttaagatt
    42721 tatagtccct ccattagtat ttttattttg caggtcaatc agaattttac ttaccctaga
    42781 tatattataa tctaagttat catcattaga aagtaagatt tttatattac ttcttgtaag
    42841 catttctata ttgctttctt tttttaagtt tacataattt atttttctat aaattccttc
    42901 ttcttttaaa taatttaaag ttttaaatac attctcctta gttttataat ttttaaattt
    42961 tatagattta ttatcatcaa tgctataatc tacatctact atcaagtctt ttttactttc
    43021 attagaacct cttagttctt ccaataaatt tcctttttta tctatataac aataattatc
    43081 ttcatctttt aatactgcaa atatttcttt ttcttttaaa cttataatta tcttattggg
    43141 aagttttctt tttatttcca cattttctat atatggattt tttataagtt tatttttcat
    43201 atctttaaaa ttgtatgcaa aaatattttc atttagattt acatttagtt ctttcattat
    43261 atttgatttg gtcaccctct tatttccaat tacatctatt ttctttacat caaataaatc
    43321 actttttaca attatacata tacaaaaaga taacataagt ataaaaacta aaactatcat
    43381 gacattattc gtatttaact ttcttctttt tttcaaatat aatcaacccc tttggttaat
    43441 aaatacacct ttagagcttg tttttcctac aaaaaaatta taatatttaa agtcaaattt
    43501 ttgcatttta ttacataaca tccaaataag gtattaaatt ttataaataa atcaatattt
    43561 catcaaaata aacatagcat actacatact atttatatat ttaaatctgt atacatacaa
    43621 ataaacccct aatttataat aatttagaaa atctaatata ttataaatta ggggtaaata
    43681 tttacttatc ttttctttat tcctattacc ttagcttgac cttctatact tggagtcgtt
    43741 tcttttttta tttcttttac ttccttaata actttttctt tttttgtttt tttagaagtt
    43801 gacttttgtg ttgaattgta tactttcatt atctcatcat atataaggtc tatggcttca
    43861 ggcttaccta tagttttact tgcatttgcc atatcaacca aaagttctct atctcctaaa
    43921 agtttaaata ctgctgtatt taggctctct ggagttagat ttttttctaa aatagcaatt
    43981 cctgcccctt gtttttctat actcttggca ttatactctt gatgattttc agcagtataa
    44041 gctttaggta ttattataga tggctttcca agagccgtta tctcagctaa tgaaattgct
    44101 cctgcgctac ctataaccaa atcacttgct gcaagtgcat ttgccatatc ttctaagtaa
    44161 ggcacaactt tttggtatgg tttaagattt atatcgctaa tacttcccat aaattcatca
    44221 taatagcttt tgcctgtagc aaatataaaa gctatatctt catttaccat attctttatt
    44281 acaagtctca ttgcatcatt tatttttctt gaacctccac taccaccata gcaaagtacc
    44341 attctttttt cgtcacttat tgatagattc tttcttgcaa tattttttct tgataataaa
    44401 atttcttttc taactggatt tcctgtaaaa actaatttat cttctgctgc ctctggaaat
    44461 cttttatgcg aatcttcaaa acttgtaagt acctttgtaa ctgttttaga taaaatctta
    44521 ttagttacac caggaaaaga attttgctca tgtattatgg ctggtatttt ccccatagat
    44581 gcattaaata aaacaggtcc actaacatat ccaccagttc ctataactat atctggttta
    44641 aatttcttaa caatctttct tgattgctcc aaacctttaa aaagcttaaa aactcttttt
    44701 acattatcga aatctatttt tcgcttaaaa ccttgaactg ttacagtctt taattcaaat
    44761 ccatacttag gaactatttc tgactctatt cccttttccg tcccaacaaa aattatctca
    44821 gcgtctggat gctcatctct tattttgttt gcaatagcta tagctggata cacgtgccct
    44881 ccagttccac cgcctgataa taaaactttc atcaaatcat catctcctgt taattaattt
    44941 tgacatgctt tgagatgttt aacactattc ctacagctcc cataaagatg gtgagtgaag
    45001 ttcctccata acttataaat ggtagtgcta cacctgtagc tggcattgat gatgtcgcaa
    45061 ctgctatatt taaagctgct tgtattccaa tttgtgcacc tatacctata acaaccatac
    45121 aagcaaatac attagaagtc ttcaaagcta ttcttacaca tctgtagact aaaactacaa
    45181 atagcataat aactattata caaccaatca atcctaactc ttctcctatt atagcaaata
    45241 taaagtcatt ttgtggctct ggtatataaa aatacttttg tttactcttt cctaagccta
    45301 gaccaaacaa tccacctgaa cctagtgcat atagaccttg tattacctga taccccttac
    45361 caagagggtc ttgaaaaggg tctaaaaatg atgtaacacg actaagtcta tagggttcag
    45421 caattactaa tgcagcaaat aaagcagccc cactccctat catagcaaat acaattttca
    45481 tatccattcc agcaacaaat atcattacaa aagtaactag aattacagta cctgctgttg
    45541 acaaatttgg ctgaagtatt atcaacgcaa aaaatatccc tggaactacg agaagtggta
    45601 caacaccttt tgtcaaagat tttattttat cataattttt ttcaattaat tttgcagtta
    45661 atattattgt agcaaacttt gcgatttctg caggttgaaa tgttaaagct cctattccca
    45721 accatctttt tgctccgttt gcttctatcc ctaaaggggt caaaactaac aataataata
    45781 ctactgctat agctccaatt gctgtagcat ttttcttcca aaaactataa tctattcttg
    45841 atgtaataat cataactata aatccaagta cagcatatat tacattcttt tttagaaaat
    45901 agtacgcatc attgtgttta aatgaagatt gtataaaact tgcactaaac accataacta
    45961 ttcctacaaa tactaaaagc atagtagtgt aaaacactac tccatcaaat tcagtcttca
    46021 cccttatgtc aatttgtttt ttcaaatttt ctttaggcat ccaactaatc tacctccatt
    46081 cttccattta agtaagttta gaggtaagag attattttaa attgtttaca ttatctttga
    46141 agtcttttcc tcttacttca aaactttcat acatatccca acttgcacaa gctggtgaaa
    46201 gaagcactat atctccactt tttgaaattt cataagaagt cttaactgct tcttccatat
    46261 cttttactat atgtatgtca ttaaatcctt tatttttagc acaattttct atatttgatg
    46321 cagtttctcc taataagacc aatgatttaa catatgactt tgcagtttca agaagttcat
    46381 caaaattact tcccttatcc atcccccctg ctataagtat tataggtcta tcataagact
    46441 gtatagcttt tatagtggaa tctggattag ttccctttga atcatttaca tatattacat
    46501 tgtctaaatt tcttacaaac tcttgtctgt gttccactcc tttaaatgtc ataagtacat
    46561 cctttataac ttctaaatca attttgcaga catatgctat tgctatagct gccatacaat
    46621 tttctaagtt atgacctcca ggtaaactta catcatcttt atttagaaat ttgattttat
    46681 catctatatc tattattatg tcattatttt ctaaatatac tcctccattt acttttttag
    46741 ttcttgaaaa gtaaattact ttggcattgc atttatcagc taaagatttt actatctcat
    46801 catcatagtt taatacacag aaatcctcaa cagtttggtt cataaatata tttgcctttg
    46861 cttctatgta tttttccata gtatggtgtc tatttaaatg gtcctctgta atatttaata
    46921 ttgcgcttac tttaggtcta aattcatcta tactctcaag ctgaaaactg cttagttcag
    46981 ttactaacac agactcttca cttgaagttt ctatagtatc tattacagga tttcctatat
    47041 taccaactac atatgtatct cgttttgctc ttgaaaaaat ttctcctacc aaactagttg
    47101 tagttgtctt tccatttgta cctgtaatcc ctataaaaat tggattatcc gatagtttaa
    47161 aagctaattc tacctcacca attatatact tgcctgaatt ttttaatttc aatatgaatg
    47221 gtaggtctag tggtacacct ggagacacta caaccatatc tatatcatct acatcttctg
    47281 ggtgatgtcc taatatgtat tttatgtcat ttatagattt caattcatca agtatatttc
    47341 tcaatttatt ttcatctttt atatcattta cgattatact tgcacccaat ttatctaaat
    47401 gtttaattgt agatatacca gtttttgcaa gtcctactaa taaaactttt tttcctttta
    47461 agtccatttt tcattccccc tagccctaaa atactgctat tatacttatc caagctaaaa
    47521 caactgttat aatccaaaaa ataaatacaa ctcttgtttc tggccaacca cactgttcaa
    47581 agtggtggtg tattggagcc atcttaaaga atctctttct tgttgcctta aaatatccaa
    47641 cttgaatcaa aactgataga gcctccgcaa aataaattcc tccaattata ggtattataa
    47701 gcactgagtt agttagaact gaaaatgcta caactgcacc tcctaatgcc attgaacctg
    47761 tgtcgcccat aaacactcta gccggatatg aattaaatcc taagaaacct aaacatgctc
    47821 caacagttgc tgctgctaaa actgcgactt ctgtatttcc agcaatagaa cttgcaaata
    47881 gcataaagaa tacagaaact attaatgtta ctcctgatgc taatccatct aatccatcag
    47941 tcaagtttac agcatttact attgctacga ttataaacat cattattggt atatataata
    48001 ttccaacatt tatcacaaaa tctgtaaatg gtatcataag ttgtgaagca cttgatgatg
    48061 atgtatactg ataaaaagca acataaaaag ataatgcaac ttgaaggatt attttttgat
    48121 atgcttttag tccaagtgat ctttttagct ttatttttat aaaatcatct aaaaagccaa
    48181 taaaaccaaa acctgcaata catataagac ctactgccat atcatgacta acttttactc
    48241 ttgtaagtcc agttattaga attgcaacaa tcattataat tccacccata gtaggtgttc
    48301 cgtttttagc tagatgtgtt tggggtccat catctctaac tgtctgacca aatttaaatt
    48361 ttctaagcat tggtataaat attggtccta ttataattac tattaaaaac gcaatcaatg
    48421 cggtgtacgt aagctctgtt attcctaaca tcataaaact cctctccctt gtcaattaac
    48481 tcattagttt aagcttattt atttagatat tcgactattt tttctaatct catgcctctt
    48541 gagcctttta ctaaaatagt gtctcctgtt tttactaatt catttaactt gttaaacaca
    48601 tcttctctat tctcaaagtg atatatattg gctgaattga atcctaattg ttttgcttct
    48661 tctccaataa acactgaatt ttcacctata gttattataa tatcagtatt attcatagat
    48721 gattttccaa ctaatctatg accatactct gaaatttcac ccatttctag tatatctcca
    48781 agtatcgcta cccttctacc tttatatctt ccaagtatct ttaaagcagc atccatagaa
    48841 tctggactag cattatatga atcattaatt attgttaatt tttcattttt tattatgtct
    48901 agtctcattt ttgtcccttt aaaatttttt aaaccttttt ttatataatc taaagaaata
    48961 tttagacaca aaccaactaa tatagcagac attgcattat atatattatg ttctcctatt
    49021 gttggtataa atatttcctc ttttttccca tctattacac atataaatgt taaactatcc
    49081 tcttccatag tataactttc acaataaaca tcattgtttt tattaaagcc aaatgttttt
    49141 aacttatata catgttcttt ttcttttaat gtagataaaa acttatcatc tccatttaca
    49201 attaaagtat ttgtttcatc aaagtttgaa gtaatctcca tctttgcttt caaaatcccc
    49261 tcttgtgaac ctagtttttc tacatgtgat aatcctatat tcgatatgac tgcaatttta
    49321 ggatttacta tatccactaa atattttatt tcattgaatc cagacatacc catctctatt
    49381 acagcacact catgttcttt atttagatta aataaagtca atggaactcc aaaatgatta
    49441 tttaagtttt tttcattttt tagtatattt aactttgcag atatggcaga gtaaatcata
    49501 tctctagtag tagtttttcc cacactacct gtaacaccta taaatggaat atcaaatttt
    49561 tctttatagt attttgaaat atctcctaga gccaaagatg tatcttttac ctctattaaa
    49621 tttatatccg aactttctaa ttttattcca ttactttcat tttttataaa agttttacat
    49681 ccactatcat atgcagactt cataaatgta tgcccatcta aattttctcc aactatggct
    49741 acaaatgcat tttgggcatt tgcctccctg ctatctataa ctatatcact tacacagtca
    49801 ttataatctc catatattaa cttcccatta gttgcaagta ctaactcttt tattgttaag
    49861 cactccatta ttaaactcct cctttaaaac cttagctata ttctcttagc aacaaaaggc
    49921 aatgtatacc gttatatata cattgcctac gataactctt aactttataa ttatatacta
    49981 tatttctgtt tttttgaaga tgtttatggg tatatgttaa ttatctgtta ctttttagtt
    50041 ttcaaaatat agggttatac ttgagtcttc attaactttt actccaggtt ttgggaatat
    50101 atcctttacc tttgtatctt ctggaagttc tatatctgca tctaagtctg gttttaactt
    50161 cgcatcctcc aatgccttta cagcatctcc tatttttaga tttcttacat ctggcacttt
    50221 aacttgcttc ttttcatact cagctttttc ttcttcttta tatactggtt taactcccaa
    50281 atattttaaa gagtcattca ttatttcttt cactattggt cctgctgtag tactaccaaa
    50341 tgcacttact cctgttggtt cgtcaacaat agcaagaact actatttgcg ggtcatcaca
    50401 aggtgctatt ccaacaaatg aacatatata ctttcctgga gcatacttac catctataac
    50461 tttttgagct gtacctgttt taccaccaag tctataacct ggtatatacg ctatctttcc
    50521 tccaccttca gttacaactg attctgcaat ttctaacatt tttttagatg tttctttaga
    50581 tataacactt cttacttttt ttggttttac tgtttcagtt atatttcctt tattgtcagt
    50641 ataagatttt accactcttg gttgcattaa atctccacca ttagctattg atgatatagc
    50701 tgttataagt tgtattggag ttactgatat agattgacca aatgatattg tagccaattc
    50761 aactggtcct acattttttt cgttatacag tattccctta gcttctcctg gtaaatctat
    50821 acctgtctta tccataagac caaatgattc tatataatca tacatttttc caacacctaa
    50881 tctgcttcct aactcaacaa atactgggtt gcaagagttt tgtactgctt gtttaaattc
    50941 ttgtgttcca tgaggtctgt aatgtctcca acatttaatc tttcttcctc caacagttac
    51001 actacctgta catgtgaatt tttctccatc tttaattact ccttcttcaa gagcactgga
    51061 agatgtaata agcttaaatg tagaacctgg ttcatatgta tcacttactg ctggatttct
    51121 ccacatttga taatagcctt ttattttatc tttatcatta tatttttcaa gttcttcttg
    51181 ataatatgga tatattggcg tccttgagtc attagggtca taatctggtt ttgatgctaa
    51241 agcaagtata tcacctgttt tagggttcat agctattgca gtaacctttt ttgcattatt
    51301 taactcataa gctttctgta ctgctttttc agtatagtgt tgaattactt catctataga
    51361 caacacaaga ccattacctt gtacaggctc ataatatttt tccattcctt gtggtatttc
    51421 tcttcctgaa gcatcagtac ttactataag ttttccaggc tttcctttta actttttatc
    51481 atattgcatt tctacaccag atatacctgt tgcatctgaa gaagtatgtc ctaacacata
    51541 tggtgcaaaa ttcccatatg ggtaatatct ttgattatct tctgccaccc atattccact
    51601 taatttagca tctcttattt gacttgcctt atcatcatct atccatcttt ttacttttac
    51661 aagagccata ttttttttgc ttattaaagc gtaaatatct ttataatctt catccaaaat
    51721 ctcagctacc ttttcggctg cttctttttt atcttctact tccacaggtt tacaccaaac
    51781 agtatactta gttacactta ctgctaactc tttcatattt ctatcatata tagttcctct
    51841 tttgggttct attggtatat ctcttgtttg ttgttctagt gcttttgtac tcaaccaatt
    51901 tcccttcata agttgtagat acccagtcct aataacaagg caaaaaaaca atgcacatgc
    51961 tagaataaga acgagtacca gccttttctt acttatcctc tttacttttc tcaaatctat
    52021 tccccctagt tatccacatc tatatacttt atttgtccat cttttggata gtccatattg
    52081 agcaattcct tagcctttag ctcaatttct tttattgatg ttttttcagt ttcttttgcc
    52141 tttagttcct ctaatactat ctcttttttt cttaaatctt tttgtaaata atagatatcg
    52201 tacttcattt ccgagatttt tgaataacca catagattca atattattac tgaaaaagtt
    52261 gcaatcagta aaatgcattt agctcctatt tttttcttat ttctcttttt ataattattc
    52321 ttttttttat ttttatattc atttagatta tgtattttat aatttttttt caaattctca
    52381 ccccgatagt atatagttta aattttcctc tatactatat ttgttattaa tcatatttct
    52441 tcctctaaaa tttcatcgct aaattaatac actattacac aatctaattg tatttttttc
    52501 tatacacaac aaaaacctat aaattcactt atacttttat atgaatctat aggttagata
    52561 ttaatttcta tttattttta tcacttctag tatttttaga taatttcttc cataaatata
    52621 atatgtaact aactatctac tctctgattc ctaagttctc cattatatta cttaatacca
    52681 tctatatcta tatttttata tctaaatttt cattatatat ctcaataaca aagaacattt
    52741 cttatagtgt taattgtttt ttaattgctt taccagtgca acaaaatata taatactttt
    52801 taattaatta taataatctt atatataaga ttattcttta gccttataac tacttatatt
    52861 ttttctgcta ctcttagctt agcacttctt gaacgtggat ttacttctat ttcttcctca
    52921 ctaggtaata taggttttct agttattatt ttcacctcag attctttatc acattggcat
    52981 ataggtaaat gctgtggaca tatacaatct gatgctaaat gcttaaatgc atttttcact
    53041 attctatctt ctaatgaatg gaatgttatt atacatattc ttccaccttc attcattata
    53101 gaagaagcat catttatcat ctttgtaatt actccaagtt cattatttac ttctattcgt
    53161 attgcctgaa aagttctttt agctgggtga ggtccatcta ttctggcttt cttagggata
    53221 gcttttttaa ttacatctac taattctcct gtagtttcta ttggtttgtt tgctctttct
    53281 tcaactataa atttagctat acgcttagcc cagttatctt ctccataatc ttttattatc
    53341 ttagttaatt catcttctgt ataagtattt acaacatcat atgcagaaaa ctcacaccta
    53401 acatccattc tcatatcaag tggtgcatct tgcatataag aaaatcctct atcagcttca
    53461 tcaagttgat gagatgaaac tcctaaatca gctaatacac catcaatttt gtaaactcct
    53521 attttttcta attcctcttt tatattttca aaattgctgt gaacaaactt cactctactt
    53581 tcatattcac tcaatctctc ttttgctgtg cttatagcat ttttatcttg gtcaaaccct
    53641 ataaataatc ccttatctga cagttttttt actatttctt tagaatgtcc tgctcctccc
    53701 atagtacagt caacatacac gccatctggc tttatattta aattctctat acactcattt
    53761 aaaagaactg atacatgatg aaattccata gttacctccc ttaaattcac tttttaaact
    53821 attcttcact aatattattt ttatttttct ttgataaata aacatgtgca attatgccac
    53881 caataactcc aattagactt ataacttgtg ccattctaag tggtcctaac attaaactat
    53941 ctgttcttaa tccctctata aaaaatcttc ctattgaata taaagttata taagtaacta
    54001 taacttgacc ttcatatttt ttattttttc taaatagtaa taaaactata aatattccaa
    54061 aatcccatat agactcatat aaaaaagttg gatgtacctt tactccatca accattattc
    54121 cccaaggtaa attggtagca cctccatgtg cttctccatt aataaaattt ccccatcttc
    54181 caatagcttg tgctaaaggc attccaagta taactgtatc agccattttt aagaagttaa
    54241 tatttttaat cttagtgtat atataaccag ctaatattcc accaattaac cctccatgta
    54301 tagcaagtcc accacctcta aaattaaaaa tttgagacat attttgagca tagtaactcc
    54361 aattaaatac aacataatag attcttgcac agattagtcc aactggaatt gctattatag
    54421 ctatatttaa tacatcatct tctttaattc ccactctttt tgcttctttt attgctatta
    54481 aagttcctaa aatcattcca catgccataa gtattccata ccacatgatg tctatgccaa
    54541 acagtgtaaa tgctactcta tccataacgt cacctctttg tattaattga aaatatttcc
    54601 aaagcaatat gctataatta caattaattg taattatact aaattatgat aacacattaa
    54661 tgttaattct acaaa
//
LOCUS       DAYAKB010000022        50707 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.022, whole genome shotgun sequence.
ACCESSION   DAYAKB010000022 DAYAKB010000000
VERSION     DAYAKB010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.022"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            213..1088
                     /locus_tag="ACGI3L_001532"
     CDS             213..1088
                     /locus_tag="ACGI3L_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HFG9197246.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            1106..2596
                     /gene="cls"
                     /locus_tag="ACGI3L_001533"
     CDS             1106..2596
                     /gene="cls"
                     /locus_tag="ACGI3L_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFG9197247.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            2789..3073
                     /gene="groES"
                     /locus_tag="ACGI3L_001534"
     CDS             2789..3073
                     /gene="groES"
                     /locus_tag="ACGI3L_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFG9197248.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            3106..4734
                     /gene="groL"
                     /locus_tag="ACGI3L_001535"
     CDS             3106..4734
                     /gene="groL"
                     /locus_tag="ACGI3L_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFG9197249.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTESAVADLPEKEDAGMPGMGGGMPGMM"
     gene            4996..5736
                     /gene="larB"
                     /locus_tag="ACGI3L_001536"
     CDS             4996..5736
                     /gene="larB"
                     /locus_tag="ACGI3L_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HFG9197250.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            5871..7003
                     /gene="larC"
                     /locus_tag="ACGI3L_001537"
                     /pseudo
     CDS             5871..7003
                     /gene="larC"
                     /locus_tag="ACGI3L_001537"
                     /inference="COORDINATES: protein motif:HMM:NF014072.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
     regulatory      7063..7164
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            7385..8920
                     /gene="guaA"
                     /locus_tag="ACGI3L_001538"
     CDS             7385..8920
                     /gene="guaA"
                     /locus_tag="ACGI3L_001538"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFG9197251.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(8997..10043)
                     /locus_tag="ACGI3L_001539"
     CDS             complement(8997..10043)
                     /locus_tag="ACGI3L_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9197252.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(10120..10335)
                     /locus_tag="ACGI3L_001540"
     CDS             complement(10120..10335)
                     /locus_tag="ACGI3L_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197253.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
     gene            10621..10752
                     /locus_tag="ACGI3L_001541"
     CDS             10621..10752
                     /locus_tag="ACGI3L_001541"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197254.1"
                     /translation="MNENENMSLYVSKLKEVLKNNSEEYKKIRAKINEIYNLNEKKE"
     gene            complement(10769..11170)
                     /locus_tag="ACGI3L_001542"
     CDS             complement(10769..11170)
                     /locus_tag="ACGI3L_001542"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197255.1"
                     /translation="MQTLAEIIKEYRSEHNLSLREFSNLCGVSHTYIDKIEKNRDPRN
                     GKAVEPTLDMLEKMSFGLNLTLKELLTKLGKIQPNTQQDDELLKKVNSKEDNEVNELI
                     NRLASLDSDDKNAIKKMIDNAYYKAVNTKKE"
     gene            11356..11547
                     /locus_tag="ACGI3L_001543"
     CDS             11356..11547
                     /locus_tag="ACGI3L_001543"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197256.1"
                     /translation="MRKESRISQKKFADKIGISRPYLSRIENGKVNPSLEIAHKISLE
                     TGKTINEIFFDFTVNHSKL"
     gene            11787..11924
                     /locus_tag="ACGI3L_001544"
     CDS             11787..11924
                     /locus_tag="ACGI3L_001544"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197257.1"
                     /translation="MQREQTTLRIPEDLHKALIDLSSDIGMPITSIIIIACWLYISKI
                     N"
     gene            complement(11910..12221)
                     /locus_tag="ACGI3L_001545"
     CDS             complement(11910..12221)
                     /locus_tag="ACGI3L_001545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197258.1"
                     /translation="MTTITVRIYTPLNENLEKISYQTGILKSSLILYAINDIIRNSKV
                     NELQSISYKSDDTVRSTLRIPGVLKELLEKTAKENNLSINSLINNVVHSFCISDWLIY
                     L"
     gene            12342..12512
                     /locus_tag="ACGI3L_001546"
     CDS             12342..12512
                     /locus_tag="ACGI3L_001546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197259.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            12515..13153
                     /locus_tag="ACGI3L_001547"
     CDS             12515..13153
                     /locus_tag="ACGI3L_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HFG9197260.1"
                     /translation="MNNLQIFEKLEFGQIRMAEIDNKPYFVGKDVAKSLGYKNTNDAI
                     LRHCKGVVKHEGFKINGIKIALITEGDVYRLIVGSNLPNAEKFESWVFDEVLPSIRET
                     GQYQAQQHVITELTGTIGDLKGTIKEYKKLCKITCSKKQQYSKYIKNRLDIDKANKEY
                     NQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIRVIKSERPYKQLSYFEN"
     gene            13212..13382
                     /locus_tag="ACGI3L_001548"
     CDS             13212..13382
                     /locus_tag="ACGI3L_001548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197261.1"
                     /translation="MKNNISDSRVKYFCKCPYCGFDNEVEVKKGLKPKICCICTKEVE
                     YEKLEQQSTPAK"
     gene            complement(13385..13618)
                     /locus_tag="ACGI3L_001549"
     CDS             complement(13385..13618)
                     /locus_tag="ACGI3L_001549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197262.1"
                     /translation="MNIGKITKIEATCFDCGTKVTITESKFREVCDNGLPCPMCKEHI
                     SNSNFIAEQALQYNHAVNKLEKELDSCKNIHIY"
     gene            13687..13884
                     /locus_tag="ACGI3L_001550"
     CDS             13687..13884
                     /locus_tag="ACGI3L_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197263.1"
                     /translation="MAINDNINKILRDRNLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKLADYLDVTLDELVGR"
     gene            13923..14129
                     /locus_tag="ACGI3L_001551"
     CDS             13923..14129
                     /locus_tag="ACGI3L_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197264.1"
                     /translation="MAKAVAKEQLFYRAKDIAKILDVCEATAYKIIGELNKELEKEGW
                     KTFPGRVSVTYFKERYCYKTKKGA"
     gene            14301..14489
                     /locus_tag="ACGI3L_001552"
     CDS             14301..14489
                     /locus_tag="ACGI3L_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197265.1"
                     /translation="MRIIYKNKIYKVEQDKVLFRITYYDEQKNNRKFNNNKKVKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            14505..14717
                     /locus_tag="ACGI3L_001553"
     CDS             14505..14717
                     /locus_tag="ACGI3L_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197266.1"
                     /translation="MVFNLEKFKVGNAIRISCERFGFEIDCIVVVATEEELNLAYFDK
                     ERGCIEYQALMPEDLRYDDYILERLG"
     gene            14733..14903
                     /locus_tag="ACGI3L_001554"
     CDS             14733..14903
                     /locus_tag="ACGI3L_001554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197267.1"
                     /translation="METAISIAKGQIEGANESIKELKSKENYDKESLRWWEGVKQASE
                     NILEFLEIENKA"
     gene            14985..16937
                     /locus_tag="ACGI3L_001555"
     CDS             14985..16937
                     /locus_tag="ACGI3L_001555"
                     /inference="COORDINATES: protein motif:HMM:NF024867.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9197268.1"
                     /translation="MKAILLKSLNIENFKGIKELRIDFNNITNVFGENATGKTSIFDA
                     FTWVMFDKDSKNRSVFEIKPLDKQNKVIRGLVTTVTAVLEVNNKEIKLTKKYEEKWTR
                     KRGESEATFTKNETTYMINDTPIKKSEYVKEVAEIANEEQFKLLTNPYFFSNELNWKK
                     GRELILNVCGDITTEQIIESNKDLTLLITEFEKENNIDKIIKNRKAIKNNLSKEKEEI
                     PVRVNECNKSMYDIDFEEIEAQLKAKKADLEAIEDMLLSGTKANEQILKDKEKIFELK
                     QETQSIKQSASEKGNKKRNELLKEKDELKYNIKNLRNNLVYLERDNELKETLKKRAIE
                     KTTNLRDKWTKKSQETLDLSVIQTECPTCKRPLDLEDIEEKKKEMLDNFNLNKAKELK
                     EIAELGKSKNDDVELFNTEIERLKVDINKTLEEIQEKAVLLDKIKKELESTKSTEIYS
                     ADEEKRLTEISAEIKELEEKINNKDADKNIDELKENKKKLTSEIELLNKELAKRDINK
                     ELLDRKEQLLEKEKALGIELAHQEKILNLCELFIKTKVSLLESNISSKFKNVTFKLFK
                     EQINGGIEETCEALINGVPFSNANTAGQINGGLDIINTLSNHFEVKMPIFVDNRESVN
                     NLIDIDSQVINLIVSNDNPLKIEGVN"
     gene            16938..17855
                     /locus_tag="ACGI3L_001556"
     CDS             16938..17855
                     /locus_tag="ACGI3L_001556"
                     /inference="COORDINATES: protein motif:HMM:NF015776.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFG9197269.1"
                     /translation="MAERNITDVVLNRVNELKDSGELVIPPTYSAVNALKSAYLILQE
                     TLDKSYKPVLETCTPISIINSLLNMVIQGLSPAKKQCYFVAYGNKLQLMRSYMGTIAV
                     TKRLSNIKDIKAYCIYEGDKFKVKYNKENAVLEIGEYEPAFENIDIGKIKGAFAVIVG
                     NEGILHTEIMTFTQIERAWLQGVGYSNPKNKVHDNFTEEMAKKTVINRACKMYANTSD
                     DSDLLIGAFNETDRVITSEEIAKDTDKEVEKEISQNANIKSLEMPSQVDNTIFTQTKE
                     KVAINIDEDKPNLAEFEEAIQVELDTPPF"
     gene            17900..18568
                     /locus_tag="ACGI3L_001557"
     CDS             17900..18568
                     /locus_tag="ACGI3L_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9197270.1"
                     /translation="MLQLENETLILECGVSYKEILKGLDFSLENVVGCLVTHEHKDHS
                     KAITELTNNGIDVYSSKGTLEALKIENHRTKIIESEKLFKIGNFKIVPFNTKHDAVEP
                     LGFLINHSSFGNLLFITDSYYCEYNFNNLNHIMIECNYSKDLLDNNKDKIYLRNRIVK
                     SHFELSNVINFLKVNDLSNIKTITLLHLSEDNSDKDLFIREIEKNVGVPVIVAEKGLE
                     IYLD"
     gene            18579..19472
                     /locus_tag="ACGI3L_001558"
     CDS             18579..19472
                     /locus_tag="ACGI3L_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFG9197271.1"
                     /translation="MAKYRILQANFWDDGFVLDLTPEEKYFYNYLLTNGRASQCGCYE
                     LPYKIMEMQTGYNRETVEKLIKRFIEYGKIKYDSTTKEILIINWSKHNFSKSPKVRTC
                     ILKEVESIKNKEFQQYMYRVCIDYGYPIDTVSIDYGEKEKEKQKEKEKQKEKEKQKEK
                     VEPLICEEQEKNELKEFKKLYEENIGVVYPVTAEWLIEISSDVDIRLFKSAIEICAEK
                     MNMNIAYLKGILKKWKDANITTYEQLESYRLQQENKKAKKVVNGQLSKNKFANFEQTF
                     TKYTENELDNIIKKSQDAKFK"
     gene            19530..19877
                     /locus_tag="ACGI3L_001559"
     CDS             19530..19877
                     /locus_tag="ACGI3L_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197272.1"
                     /translation="MGKIWMDAGTFLETKDIGDIECNLREMINKNKQKNLIGRINSKG
                     QGRKSKKVECTNIITGESKIFVSAVEASEYLYFTELHITRLARTGKTTKNGWKVRYIE
                     EVSNGISKCGTSN"
     gene            19846..19983
                     /locus_tag="ACGI3L_001560"
     CDS             19846..19983
                     /locus_tag="ACGI3L_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197273.1"
                     /translation="MVLANVEQVIKLAEKILSKKKCSVNKAIDIAIKILNRYEYEGMI
                     K"
     gene            19980..20429
                     /locus_tag="ACGI3L_001561"
     CDS             19980..20429
                     /locus_tag="ACGI3L_001561"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197274.1"
                     /translation="MSLIEYRGYDFENKKWIYSKTIMWSNAVDCLLMLKEDFKWRKVC
                     NVGICSEEWAGNNQEIFEGDILKENYNPHNRSSYGIVKRDFNSIKLYLEWHYLKKFEG
                     EWIEIIDKTEIYHSRGYKVIGNEYENLEEVRKEFLERKEMLENERLS"
     gene            20413..20538
                     /locus_tag="ACGI3L_001562"
     CDS             20413..20538
                     /locus_tag="ACGI3L_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197275.1"
                     /translation="MNVLASLILIVGSFIAGRVYEYRLNLKEFENYDNIGGFKNE"
     gene            20531..20689
                     /locus_tag="ACGI3L_001563"
     CDS             20531..20689
                     /locus_tag="ACGI3L_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197276.1"
                     /translation="MNDRLEMINASVNYIQMICESSNIAIIAEHDRVRILDLETKEKY
                     DLLRSEGD"
     gene            20693..21016
                     /locus_tag="ACGI3L_001564"
     CDS             20693..21016
                     /locus_tag="ACGI3L_001564"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197277.1"
                     /translation="MSKVIQCDFCKEIFEKYNGECIELYKKDCSKGVLGIDKHICPTC
                     YEKFIEGKIEKVENAKRFKDKLIDFLVEHEVCDCCACDCVFDSNDEKKCKAGIREWVE
                     SEVEE"
     gene            21018..21317
                     /locus_tag="ACGI3L_001565"
     CDS             21018..21317
                     /locus_tag="ACGI3L_001565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197278.1"
                     /translation="MAKLIVSIPLTKYLKDITKEWGETYITKTYGGHVYLSDEAPGEV
                     FKKEDDLNYIEFNDSDIVMRLPKEVHQHINLKKGCNKNLKDVLKEIKKIEEKTNI"
     gene            21425..22321
                     /locus_tag="ACGI3L_001566"
     CDS             21425..22321
                     /locus_tag="ACGI3L_001566"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFG9197279.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFKGRRSSLFFAVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLIELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFVVGHFRGRSTRKVFPIERKSRKNLEQLNNPTHSTSGVLVNAVLTPDRVNKRQN
                     GRRIKESGEPMFTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDSQ
                     LYKQAGNAVTANVVYEIAKRMG"
     gene            22400..22621
                     /locus_tag="ACGI3L_001567"
     CDS             22400..22621
                     /locus_tag="ACGI3L_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197280.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKQKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYYCDGGIEI"
     gene            22618..23622
                     /locus_tag="ACGI3L_001568"
     CDS             22618..23622
                     /locus_tag="ACGI3L_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFG9197281.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRTVVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNAILESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSISFEEDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDEYHLKVLDKDAEKEEANSKFVTEFLNATKVKDDKYRTKKFKDTVENWITNVL
                     GNDIKQAEDIRSILNYTLKEKHEIDIKDFVDKSIKDDELKNSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIIIKNVNFYNEK
                     "
     gene            23633..23923
                     /locus_tag="ACGI3L_001569"
     CDS             23633..23923
                     /locus_tag="ACGI3L_001569"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197282.1"
                     /translation="MENKDNFVLNKLGPASKVMKKVEIDEKEIKSYLKELKECEEVKV
                     FIIRKDGIEIPIVFKDGNMNEWLRKEIEISFDRFKDEIAQVKKALIKVTGEN"
     gene            23943..24110
                     /locus_tag="ACGI3L_001570"
     CDS             23943..24110
                     /locus_tag="ACGI3L_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197283.1"
                     /translation="MTNKEMCKSNNLDEREVCKEFGKEICGSCINDRVDCESKDCDIA
                     YENWLEKNTER"
     gene            24196..24537
                     /locus_tag="ACGI3L_001571"
     CDS             24196..24537
                     /locus_tag="ACGI3L_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HFG9197284.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNLKVCESYIEGKNELYK
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELIK
                     INSHLELEDLN"
     gene            24663..25070
                     /locus_tag="ACGI3L_001572"
     CDS             24663..25070
                     /locus_tag="ACGI3L_001572"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFG9197285.1"
                     /translation="MKVFLVIDGEPVGKERPRMNTYAKRTYTPNKTKNYEDLIKWLYQ
                     SKVKYYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVIKVVADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
     gene            25172..26026
                     /locus_tag="ACGI3L_001573"
     CDS             25172..26026
                     /locus_tag="ACGI3L_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFG9197286.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRELKHINELINNNIKRFKTNIDIIDLKVSRSERLGDLKANPFEGLGYEDVGYSKQS
                     FNQSRNIYLLSERGYSKLLKILEDDKAWEQYEKIVDGYFSMRKELNNPLLSASKELQA
                     IFMLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKA
                     YKNKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNNYKLPIVFEEEIRLL
                     NSQLSIVS"
     gene            26178..26684
                     /locus_tag="ACGI3L_001574"
     CDS             26178..26684
                     /locus_tag="ACGI3L_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197287.1"
                     /translation="MSKTKKEFFNATKKQLSNYKQLSANIIKLKNEIQMLKDNSVGDL
                     MKGISYDSVKTGKTNKTSNMIEDAIVNVSDLITEKEIELYEAEIIKSTIDLAIRNLKP
                     IHRQIIELKYIDGLMWQEMVDIVHLEERQLSVRASQAISSISIALFGKKALIEQEPLF
                     ELLDYKLN"
     gene            27437..27610
                     /locus_tag="ACGI3L_001575"
     CDS             27437..27610
                     /locus_tag="ACGI3L_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197288.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            27610..28221
                     /locus_tag="ACGI3L_001576"
     CDS             27610..28221
                     /locus_tag="ACGI3L_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFG9197289.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEDFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLTNSLARKVVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            28298..28924
                     /locus_tag="ACGI3L_001577"
     CDS             28298..28924
                     /locus_tag="ACGI3L_001577"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197290.1"
                     /translation="MKKITKLILCSLLVISIASPLQVEAKTTHHSSSHVSIHKSSTKS
                     KSSRPKITKTKKATKTYRTNKSIKKKIKLKKQVNKKTQVPNKQAARKDKKTTTYNYYN
                     SYNSNRYYTTSSSGLSFWDCYMLGHLFNNNNKVSEQDIARELQKQGYSKQETDNILRK
                     ANQNQAKKEEKKKRVMMLIFSVLGALFIIGLGLIIFIKRESKGCNKSM"
     gene            28997..29686
                     /gene="terS"
                     /locus_tag="ACGI3L_001578"
     CDS             28997..29686
                     /gene="terS"
                     /locus_tag="ACGI3L_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFG9197291.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKHNVSLSTVKSWATRYWKQKG
                     CNQSKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELMQEISIKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELK
                     ISVDYGDRNDS"
     gene            29676..30917
                     /locus_tag="ACGI3L_001579"
     CDS             29676..30917
                     /locus_tag="ACGI3L_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HFG9197292.1"
                     /translation="MIVRVNFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDYILKL
                     GDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIKSKVT
                     GNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGILTNP
                     NLYYQMTFTFNPVSSTHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQMRKEQ
                     DPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANVVLRIGF
                     KDGELYICNEIYVHEMDTSEIIKIANSKGLEKNIFMYCDSAEPDRIKMWKSAGYKAKG
                     VKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEFMDDA
                     MAALRYSIDNKLKNNGISFLK"
     gene            31004..32362
                     /locus_tag="ACGI3L_001580"
     CDS             31004..32362
                     /locus_tag="ACGI3L_001580"
                     /inference="COORDINATES: protein motif:HMM:TIGR01538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9197293.1"
                     /translation="MEHYILKHRPEKYKQGEEYYYGNADINNKRRYYLLDGAKVDDFT
                     KVNNKAINNYHKLLVDQKVGYSVGNPIVFNADDDNLTKLLNDLLGEEFDDTITELYLN
                     ASNKGVEWLHPYINRKGEFKYVIIPAEEAIPIWDSKRQRELVAFIRFYYIEDIDGNKI
                     KRVEYYTENDVTYFIERGNSFIQEFLYDEYGKMTDIQEGHFRINNKEQGWGKVPFIPF
                     KNNEKCVSDLTFYKSLIDIYDNNISTLADNLDEIQEVIYVLKEYPGTSLQEFIDNIRY
                     YKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKNIIIFGQGVNPESQNTGDKSGVALK
                     FLYSLLDLKCSKTEKKFKKAIRELLWFVCEYLKISGNKSYDYKTVQITFNHSMIINEA
                     EKIDMAAKSTGIVSDETIVSNHPWVEDVNDELERLKKQEDTQKEYDDLIPNNQDGVID
                     ET"
     gene            32352..33713
                     /locus_tag="ACGI3L_001581"
     CDS             32352..33713
                     /locus_tag="ACGI3L_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFG9197294.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSIKYYLELEKQYKLAMSNIEKDI
                     LIWYNRFTENEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKVLV
                     NEFSKKFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCHCRTTTAPWFEDEEGYRAARDENGKTYYVPSGMKYK
                     EWYEKTFITDKKDDILSNKSWLKADFPTEKKFKKHVEKHLNEYGNITAEEYLSTARNL
                     LSEQLSNDVEGFLSKDNFLFKYRKSTNDFAVGRADGKISTLFKPKEGYNYWLEQIKEY
                     KEV"
     gene            33716..33877
                     /locus_tag="ACGI3L_001582"
     CDS             33716..33877
                     /locus_tag="ACGI3L_001582"
                     /inference="COORDINATES: protein motif:HMM:NF025569.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPCC family cysteine-rich protein"
                     /protein_id="HFG9197295.1"
                     /translation="MNCPVCGKDVDVFDICDNCNWQNSGPKETNYKGPNKMSLKEAKE
                     AYEKGKKVI"
     gene            34209..34601
                     /locus_tag="ACGI3L_001583"
     CDS             34209..34601
                     /locus_tag="ACGI3L_001583"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197296.1"
                     /translation="MAKFKKKSEEVEAFKWILGSPNTPIWFYQAFEKGTIWLDESLNS
                     VNRKGEVKKTICIKYKNGVIRATNGDWIIKDSEGKIYSCTCDEFEKYYKDLDNETKIS
                     NGGLECLREIALKDVNFKFELTGIKEEK"
     gene            34602..34799
                     /locus_tag="ACGI3L_001584"
     CDS             34602..34799
                     /locus_tag="ACGI3L_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197297.1"
                     /translation="MFYLLLQVISICLSITVFMYVTGNIVFKIYLKSLRKEYESNIHE
                     VSDEILKRIRKELNKSLDESL"
     gene            34842..35072
                     /locus_tag="ACGI3L_001585"
     CDS             34842..35072
                     /locus_tag="ACGI3L_001585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197298.1"
                     /translation="MKEYMIWFKSGNSISGIVDEDVADKLMQDFMEADSDCKDLKVYL
                     DEDGTTVIDLSQIEAISINNCNENNNIGFSKS"
     gene            35117..35680
                     /locus_tag="ACGI3L_001586"
     CDS             35117..35680
                     /locus_tag="ACGI3L_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HFG9197299.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTITKEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            35692..36591
                     /locus_tag="ACGI3L_001587"
     CDS             35692..36591
                     /locus_tag="ACGI3L_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HFG9197300.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            36591..36824
                     /locus_tag="ACGI3L_001588"
     CDS             36591..36824
                     /locus_tag="ACGI3L_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197301.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            36834..37235
                     /locus_tag="ACGI3L_001589"
     CDS             36834..37235
                     /locus_tag="ACGI3L_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197302.1"
                     /translation="MENNMIDDIERRLQGFGYVLKDGDKWLIDFVREKIENIIKLDCN
                     ISEIPKELHNIEIDMIAGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLVAYLTTYGKNNILTFRCLRW"
     gene            37229..37576
                     /locus_tag="ACGI3L_001590"
     CDS             37229..37576
                     /locus_tag="ACGI3L_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197303.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            37576..38001
                     /locus_tag="ACGI3L_001591"
     CDS             37576..38001
                     /locus_tag="ACGI3L_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFG9197304.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            37994..38431
                     /locus_tag="ACGI3L_001592"
     CDS             37994..38431
                     /locus_tag="ACGI3L_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFG9197305.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            38415..38600
                     /locus_tag="ACGI3L_001593"
     CDS             38415..38600
                     /locus_tag="ACGI3L_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197306.1"
                     /translation="MIILNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELY
                     SFSEVEEIINKFMKGVS"
     gene            38601..39911
                     /locus_tag="ACGI3L_001594"
     CDS             38601..39911
                     /locus_tag="ACGI3L_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HFG9197307.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVGVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            39933..40403
                     /locus_tag="ACGI3L_001595"
     CDS             39933..40403
                     /locus_tag="ACGI3L_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFG9197308.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            40456..40713
                     /locus_tag="ACGI3L_001596"
     CDS             40456..40713
                     /locus_tag="ACGI3L_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197309.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            40718..41158
                     /locus_tag="ACGI3L_001597"
     CDS             40718..41158
                     /locus_tag="ACGI3L_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9197310.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPILNKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            41420..42211
                     /locus_tag="ACGI3L_001598"
     CDS             41420..42211
                     /locus_tag="ACGI3L_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9197311.1"
                     /translation="MGLFSKKNKKPCCICGSEKGLMPSIEGENFCTACNCKYIDFSEN
                     ILKVTSIMKMMSNSEGMKKFIEVEKKNLKLLEKFTETKSINSSISFDEEQNLLKISYK
                     NRNQILVEKIIKFDDILEFELLEDGETIVKGGLGRAITGGVLFGGTGAVVGGITGKKT
                     SRKVVEIFKIKITVKDINNPIEYINLINSKVKTNSSIYQKAFSDAQEILSILSIITKY
                     NVMEDKKKSISSSTADEILKYKNLLDMEAITQEEFDAKKKELLNL"
     gene            42278..44620
                     /locus_tag="ACGI3L_001599"
     CDS             42278..44620
                     /locus_tag="ACGI3L_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFG9197312.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQLSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMVFGAIQKKIEDTVSSRGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGTSLVVQGLGWIITQALSVANVFSRNWSIISPIILG
                     VVSAISTYIIALGIMQAVTIAGTVANWMSWTSEVIRQRGILGTARALAIGKAEQWGFN
                     AAIYACPIFWIVLGIIAVISAVFILVAVYNHFAGTSISAISLIVGAWYWLCAVVYNVI
                     VGIVNAINICVVEIANIFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVQQINKIPGIDLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKFKDTFDISKIAEKAKKDLGLDDLWDKKYGLGD
                     GLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            44636..45337
                     /locus_tag="ACGI3L_001600"
     CDS             44636..45337
                     /locus_tag="ACGI3L_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFG9197313.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDADNGSDVKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPTPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     VPKYTIYKGQVLKLG"
     gene            45330..47303
                     /locus_tag="ACGI3L_001601"
     CDS             45330..47303
                     /locus_tag="ACGI3L_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9197314.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDEFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLDLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGSIFVKYSNAYK
                     VNAALMAAISIHETGNGSSSLCKNKNNFFGMKGMSFGSVDEGIKRGISNLSRNYIHMG
                     RKTLESIRDKYAPLYDSPLNKHWVPGVNKFYKQITGNAYSSNSAGTGVRSNEEAEKNL
                     KDITYQVQNSNNANTSTNNNSKVNKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAF
                     KRGAGINLKRVSADQSNDSRGKLLCNINDVKAGDLVFFAYNQGKGNVHHVGLCIGNDK
                     FIHSPNTGDVVKISSLSGRQKQKHDFARARRFF"
     gene            47317..47577
                     /locus_tag="ACGI3L_001602"
     CDS             47317..47577
                     /locus_tag="ACGI3L_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HFG9197315.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESINPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKVVLIRMQGGQQYLVLDRM"
     gene            47582..48001
                     /locus_tag="ACGI3L_001603"
     CDS             47582..48001
                     /locus_tag="ACGI3L_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HFG9197316.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFQNVKGKVHCKFTVYSKYGNIKAEKVVSV"
     gene            48002..49051
                     /locus_tag="ACGI3L_001604"
     CDS             48002..49051
                     /locus_tag="ACGI3L_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFG9197317.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPIDSRFNLGE
                     YNYVAIERISEKTYKMKCETTGPVFELGQLIPIEYVDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSSDLVNLVQEEIDPLQNQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINSIASNL
                     NVDKDSIVLRGEVVG"
     gene            49044..49661
                     /locus_tag="ACGI3L_001605"
     CDS             49044..49661
                     /locus_tag="ACGI3L_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HFG9197318.1"
                     /translation="MDKEINLINYLPQILRDKEEYIKVFNVENKEIKTLHEKLNDLSN
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            49673..50665
                     /locus_tag="ACGI3L_001606"
     CDS             49673..50665
                     /locus_tag="ACGI3L_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFG9197319.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELNTRIDTENEKQNIKIDQLIAGGSNVSHTHIIEIDDWILNNETN
                     MYEVTINHPLLTKRILIALYDEIGEALTPNARAIDDNSILVRNEENIKMYVYLINGNA
                     ETHFINATVDDNRVSEMTTYSSKKIEDRFLNLEEKVNGGLSSIATSVNELITYC"
BASE COUNT        20759 a         5260 c         9584 g        15104 t
ORIGIN      
        1 atttcgataa gtttaagtgg gtataaactt atagaaattc attttttatt taaggtaaaa
       61 atttaaagta aaatattatt ttacataata ataaccttat aaattttgaa attacttatc
      121 tttgtgttaa aataagtaaa atgcacatat tagagctaag tttttaagta aataaacaaa
      181 atgaaaatat aaatattaag gagatttggt atatgaatgt ttatgaaaaa ggtaatggag
      241 ttatactaga aggagtaaca gattttgacc cagtacatat atttgagtgt ggtcaatgtt
      301 ttagatggca caaacaagaa gatggctcat acactggagt tgcaaaggga agaatattaa
      361 atgtcaaaaa agagaatgat aaaatatatt taaataatac taatttaaag gagtttaaca
      421 gcatttggta taattacttt gatttaggaa ctgattatac agaaataaag aataagctaa
      481 aaaatatgga tgaatattta aataaggcta ctgaatttgg atggggaata agaatattaa
      541 gacaagatgg atgggaaatg cttatatcat ttataatttc ctctaataat aggattccta
      601 tgatacaaag agcgatagaa aatttatcaa gaaagtttgg taagtatata ggtgaatatg
      661 aaggtaatga atactatgca ttcccaacac cagaagaact aaataaggcc tcacaagagg
      721 aaataagagc atgtcaaaca ggttttagag ataagtacat aaaaagtact acacaggcag
      781 ttatagagaa taatgatgag gtatctgaat atacaaattt aagtacagag gattgtagaa
      841 aagagctttt aaaatttaat ggagtaggac caaaagtatg tgattgtatt gcattatttg
      901 gtatgcaaaa atatgattct tttccagttg atgtttgggt taagagagtt atgcaagaat
      961 tttatataga tgaagacatg agtttaccta aaatgagaac ttatggaatc gataaattta
     1021 aagaaatgtc tggatttgct caacagtact tattttacta tgcaagagaa ctcggtatag
     1081 gaaaataaat taagggggag aaattatggg agtaatagga acaatatttc tgttctattt
     1141 aattatatca tatctagctg gagccataat ttctgtgatt atattgcttg aaaatagaga
     1201 ccctgcaaaa acaatgtctt ggctattgat gtttattata tttccaggtg taggtttaat
     1261 gatatatgct atttcaggta gaaatattag aaaaagaaaa ttatttaaga ctcaaaaact
     1321 agctaataat ataaaagaaa agaaactatt tgatacatta gaaaagataa cagaaatagt
     1381 tgaattagaa aaagaatcta taaaacaaaa taagctttta agagatgaag aggatggtag
     1441 ttatagaaaa agggtaataa atatgttgtt aaagactggt atgtttccct ttactaaaaa
     1501 taataaagtg gatgtatttg tagatggaaa tgaaaagttt aaaagactta tagaagatat
     1561 aagagaagct aaagaccata ttcatttaga gtactttatc atcaaagata gtgaaatagg
     1621 tagggtgtta aaagaagaac ttataaaaaa ggctaaagaa ggcattaaga taagaatttt
     1681 atatgatgat gtaggatgct ggagattttg gtttaataga aaattttttc gagaaatgag
     1741 ggaagtaggt atagaaattg cagcattttt acctacaaaa tttcctataa taggagggaa
     1801 attaaactat agaaatcaca gaaaaattgt tgttattgat ggaataattg gatatacagg
     1861 tggaataaat ataggagatg aatatttagg caaaaatgat aagtttggat attggagaga
     1921 tactcatatt agaattaagg gtatttctgt atacatgctt caaatgacat ttctgattga
     1981 ttggtattat acgacaaaag aagtattagt gactaaaaat tatttcccaa gtgtagggaa
     2041 tgttggtgaa agtatgatac aagttgttgc gagtggtcca gacagtgact gggaagatat
     2101 tcattatgct tatttttctg caatatgtca ggctagaaaa aatgtttata tagaaactcc
     2161 atattttatt ccagatgaaa gtctactaaa agctataaag agtgctgctc ttagtggagt
     2221 tgatgtgaga ataatatttc ctaaaattgc agaccacaag atagtaaata tagcatctta
     2281 ttcatatttt gaagaaatat taagagcagg tggtaaagtt tatttatata ataaaggatt
     2341 tatacattct aaagtcgtaa taatagatga taaaattgct tctgcaggta cagctaatat
     2401 ggatttaaga agttttatgc ttaactttga ggtaaatgca tttatctatg atgaagaagt
     2461 tattagggta atgacagatg atttctttga ggatttaagt cactgtgaag aacttaattt
     2521 ggaggtattt aagaatagaa atatcataca aaaaatcaaa gaatctgtag caagattatt
     2581 ttcaccaata ttataaaaaa ttattaaaaa aggtattgaa aattatgtgt gattggtata
     2641 ttataataat tgttagcact ctattagata gagtgataat aaataaaaag tatatatata
     2701 aatctacata tataagtagt attaatttaa aaataactaa aaacataggc gaactagtct
     2761 atacttaata ttttaggagg cgtgaataat gaaaataaga ccattagctg acagagtagt
     2821 aattaaaaaa gtagaagcag aagaaaaaac tgcaagtgga atagttttac caggagcagc
     2881 taaagagcaa cctcaaatag ctgaagttgt agaagttgga ccaggtggaa tagttgaagg
     2941 gaaagaaata aaaatggaat tgacagtagg agataaggtt atattccaaa aatattctgg
     3001 aacagaagtt aagatagaag gacaagaata cacaatacta agacagagtg atgtattagc
     3061 tgttattgaa taaatataga ataaatttat taggaggggt ttaaaatggc taaagaaatt
     3121 aaattttcag aggaaacaag aagagcttta gaagctggtg taaataaatt agcagataca
     3181 gtaaaagtaa cattaggacc taaaggaaga aatgttatat tagataaaaa atttggttct
     3241 ccacttataa ctaatgatgg agtaactata gcaaaagaga tagaactaga agatagattt
     3301 gaaaatatgg gtgctcaatt agttaaagaa gtagcaacta aaactaatga tgtagctgga
     3361 gatggtacta caactgctac agttttagca caagctataa taagagaagg tttaaagaat
     3421 gtaacagcag gggctaaccc aatactttta agaaaaggaa tacaaaaagc agtaacagta
     3481 gcagtagaag aattaaaaaa tcaatcaaga atagtagaaa cacaagaggc tatatctcaa
     3541 gttgcttcta tatctgctgg tgatgaagaa gttggaaaat taatagcaga agctatggaa
     3601 atagtaggta aagatggagt tataactgtt gaagagtctc aaactatgaa tactgaatta
     3661 gatgctgttg aaggtatgca gtttgataga ggatttgttt ctgcatatat ggttacagat
     3721 gtagataaaa tggaagcagt tttaaacgac ccatatatat taattactga taaaaaaata
     3781 tctaacatac aagaattatt accagttctt gaacaaatag ttcaacaagg taaaaagtta
     3841 ttgataatag ctgaagatgt agaaggtgaa gcattatcta cattagtagt aaataaatta
     3901 agaggaacat ttgatgtagt agcagttaaa gctccaggct ttggagatag aagaaaagaa
     3961 atgcttcaag atatagcaat acttacaggt gctcaagtaa tatcagaaga attaggttat
     4021 gatttaaaag aagctgattt atctatgcta ggtagagctt catctgttaa ggtaactaaa
     4081 gaaagtacta caatagtaga tggttctgga gataaaaaag ctatagaaga tagagtaact
     4141 caaattaaac atcaagtaga gcaaactact tcagattttg atagagagaa attaatggaa
     4201 agattagcta aacttgctgg aggagtagct gttgtaaaag ttggagctgc tacagaagta
     4261 gagttaaaag aaagaaagtt aagaatagaa gatgctctta atgcaactag agcagctgta
     4321 gaagaaggaa tagtagctgg tggaggaact gcttttgtta gtgttatacc agcaatagga
     4381 acactaattg agagtttaga aggagaagtt aaactaggtg ctcaaatagt taaaaaagcg
     4441 ttagaagagc cattaagaca aatagctata aatgctggtc ttgaaggtgc tgtaattgtg
     4501 caaaatgttg ttaattctga agcagaaact ggatttgacg cattgaatga aaaatatgta
     4561 aatatgatag aagctggtat agttgaccca actaaagtta gtagaagtgc tttacaaaat
     4621 gctgcatcaa tagcaagtac tttcttaact actgaatctg ctgttgctga ccttcctgaa
     4681 aaagaagatg caggaatgcc aggaatgggt ggcggaatgc ctggtatgat gtaatttaaa
     4741 aaatttaaaa tataaatttt aatataaaga actatttcga cttagatttt aaactctaag
     4801 ttgaaatagt tcttttgtat atatctaatt tttgtatatc tataaattca atacacatat
     4861 ttagataatc agtatctagt ttgtaataat attttagagt agtattgtta ttttttaggt
     4921 tatgatttta gatatatatt aattaaggta taattgttga tagagaataa atcaaattta
     4981 aaaggatgcg ataatatgga cttaagaaaa ttgcttgaag aagttaaaaa tgaaaatatt
     5041 gatatagatt ttgcgttaga aaagttaaaa gatttacctt atgaagacct tggatatgca
     5101 aatatagacc atcatagaga attaagaaat gggtatccgg aagttattta ttgtgaaggt
     5161 aagagtgatg agcatatttt agggattatt gataaaatga atcaaaaaag ttctaacata
     5221 ttggggacaa ggtgcagaaa agaaactttt ctgaaaatta aagaaatcta taatcatgct
     5281 gagtacgaag aggcgtctaa aattcttaag attcaaaatc atgatataga gaatatagga
     5341 aaaggtaaaa ttgtgattgc tacaggggga acttctgata taccagtagc agacgaagct
     5401 tatcatacag ctaagttttt aggtaatgat gttgatagaa tatatgatgt tggagtggca
     5461 ggtatacata ggcttttaaa taaaagacat aaaatagata gtgctagagt aatagtagcc
     5521 gttgcaggta tggaaggtgc tcttgcaagt gtaattggtg gactggttga tgttccagta
     5581 atagctgttc caacttctgt tggatatgga gcaaattttg gaggattagc agcattgcta
     5641 gctatgttaa atagctgtgc atctggaata tctgttgtaa atattgataa tggatttgga
     5701 gcaggatatt tagcatcaat gataaataaa ctgtaaatac attgatataa attaaacaaa
     5761 actatataat aaaatttaat ttctattata tttttactat taaaattgag gagacatata
     5821 tgagtgaaaa aatactttat tttgatataa taagcggtat atcaggggat atgacccttg
     5881 caagtttatt aaatttaggt gtgcctaagg aaattttttt ggaggaaatt cataaactaa
     5941 gaatgagcga tgaatttaat ataaacatca gctcgaaaac tgaaaatgga atagtaggta
     6001 caaaagtaga agtaattaca aaagaaaaac atacacatag aaatttagtg gatatatttg
     6061 aggttataga taaaagcact ctaaacgaaa atgtaaaatc taaagcaaaa aaaatattta
     6121 tggtaattgg agaagcagaa gcaaaagttc atggaactac aatagacaag atacattttc
     6181 atgaggtagg ggctatagat tcaattgtag atatagtagg agcttctata ttagttgact
     6241 tactttgtgt agataaagtt tgtgctagta cagtgtctgt tggttcagga tttgtaaaat
     6301 gtgaacatgg aattatacct atacctgcac ctgcaactat agaaatttta aaaggtgtgc
     6361 caattaaatt aaataatgta aatggagaat gtacaactcc aacaggagct gcaatcataa
     6421 aagttttgtg tgatgagttt gtagatgagc ttgaattttc tccaaagcaa attggatatg
     6481 gtataggtca taagaagttt gaagtaccaa atatactcag aactgtatta ggtgaaaaaa
     6541 aaaagaagaa ttaatttatg aaattagtgc aaacattgat gatatgtctt cagaaatcta
     6601 ttcttatttg tatgaaaaaa tattagatga gaaagcattg gatatttata cagagagcat
     6661 ttatatgaag aagaatagac cagcaacaaa agtatcaatt ttatgtagtg aatcagattt
     6721 agaaaaattt attaaaatat tacttttaga aactagtact tttggagtga gatataatgc
     6781 atataataga gaaattctag agagaaaatt tgtaaaatta gatacaaaat atggagtggt
     6841 tacagtaaaa ctagggtatt ataaaggaaa actagtcaag gctactccag aatataatga
     6901 atgtaaaact atagcaaaaa atgaagatat tcctataaaa aaagtgtttg ctgatataaa
     6961 ttttagaata aaagaagaat ttagtgaaaa cttattgaca taagtaataa attttgataa
     7021 attaatattc agccttatta aataaaagta aacagaaaaa aatatataaa atataaactc
     7081 actcgtatat gctcagaaat atggtctgag agtctctacc aagataccgt aaatatcttg
     7141 actatgagtg aaattattat accaaaagac ctagttaagt aaatgtgtag gctgagttaa
     7201 actccctatg tgttggctat aagataaagg tattttggaa gcctgtatag taatttcact
     7261 tttgctagaa attatggaag ttactataca ggttttttgt gtaaaaagat ttaatataat
     7321 ttagactgta ttgtgttaaa ataaatatat aaaaactata ttatacaagg agagatgtga
     7381 atttatgaaa catgaattag tacttgtaat agattttgga ggacaatata atcagttgat
     7441 agctagaaga gttagagaaa acaacgtata ttgtgaaata cttccatgta ctgcaagcat
     7501 agaaagaata aaagaaaaaa atcctaaagg gataatattt acaggcggtc caaatagtgc
     7561 gtatttagaa gattctccaa caatatcaaa agaaatattt gaattaggag taccaatact
     7621 tggaatatgc tatggtattc aaataatgtc tcatgtattg ggtggagttg taagaaaagg
     7681 taataaacaa gaaaaagaat atggaaaaac agctataact tatggaaaat catcattatt
     7741 tgaaggaata actacaaata gtgtatggat gagtcataca gatttaatag aaaaagttcc
     7801 agaaggattt actatagttg caaatactaa tgattgtcca gtagcagcta tggaaaatgt
     7861 agaacgaaac ctatatggag ttcaattcca tccagaggtg gaacactgtt tggaagggga
     7921 taagatactt acaaacttct tatataatat ttgtaaagta aaaggtgact ggactacaga
     7981 ttcattcata gaagataaaa taaaagaatt aaaagaaaaa ataggcgata aaaaagcttt
     8041 atgtgcttta agtggaggag ttgattcttc tgttgctgca gttcttattc ataaagcaat
     8101 tggggacaac ttaacttgta tatttgttga ccatggttta cttagaaaaa atgaaggaaa
     8161 tgatgtagaa agaatattta gagagaaatt tgatataaat ttaataagag ttaatgcaga
     8221 agatagattc ttatctaaat taaaaggagt ttctgaacca gaagctaaga gaaaaataat
     8281 aggtgaagaa tttataagag tatttgaaga agaatcaaat aaattaggaa aaatggattt
     8341 cttagtacaa ggaacaatct atccagatgt tatagaaagt ggacatggaa atgctgctac
     8401 tataaagtct catcataatg ttggtggaat cccagaagat gtagacttcc aagaaattgt
     8461 agaaccatta agagagttat ttaaggatga agttagaaaa ataggattag agcttggtat
     8521 agaagaagga ttaatattta gacatccttt cccaggacca ggtctaggaa taagagttat
     8581 aggtgatgta actaaagaaa aatgtgatat attaagagaa gctgatgctg tttatatgga
     8641 cgagcttaga aaagcaggtt tatacagaga aatatggcaa gcttttgcaa cattaccaga
     8701 tgttaagact gttggagtta tgggtgatga aagaacatat gcttatttag ttggtttaag
     8761 agcagttact tcttctgatg gaatgacttc tgactggtat aagatgcctt atgatgtatt
     8821 agaaagaatt tctaatagaa taataaatga agttgatgga gtaaatagag tagtttatga
     8881 tataacttct aaacctcctg gaactattga atgggaatag taaataaaaa agtcgtaagc
     8941 cttgtatttt caaggtttgc gacttttaaa aaaatctttg tgatactaaa atgatactat
     9001 atatttaaat tatctagttt ttgggcaact tcaagttgct tatttgggta taaatgtgaa
     9061 tatgtattcc aagttgtttc tactttttca tgccccaatc tttctgctat agttaatata
     9121 tttacatcca tatttaccaa taatgacgca tgagaatgtc tcaaatcatg cactctaatt
     9181 ctttttacat tagataactt acagcatcta tctagctctt tagaaagata acttttagca
     9241 aatttaaata ttctttcatt atcttttaag tcatatagct tagatagata atcttttata
     9301 ttattatata agaaatgtgg gatagggaca acacgtttac ttttaggagt tttaggagaa
     9361 gaaacaatat cctctccatt tagtcttatg tagctttttt cgacgcttat tttattttcg
     9421 aaaatatctt ttggagtaag agctaacaac tcccctagtc taagacctgt ccaaaataaa
     9481 atttcaaatg ctagtctagg ttctgatttc ttttcaaatt caataaattt tttaaactct
     9541 tctaatgtcc aaaagttcat ttcatctgcg ttttttttac cgatagaacc tgccaaatga
     9601 gcaggattag aaggtaagtt ataatattta actgcataat ttaatacagc aacaagctgg
     9661 ttgtttatcg ttttaatata tgtttggcta taatcacttt ttaataattc gttttgccat
     9721 cttcttatat gtgttgcagt aatttcattt atttttagac ttttaaaaaa aggtaaaatt
     9781 ctaaagttta ttaaatactt tttagtttct aatgtagata attttaatct agaagacata
     9841 tcgtgcatgt attcttctat gagactttca aaactcatat cagtactcat tttagattta
     9901 ttcaaaaatt ctctttcaaa ctctagagct tcttttttag ttttaaaacc tctcttaatt
     9961 ttctttttcc tatccccatc gaagtctgta aaataaaagc tagcatacca actttttctt
    10021 tgttcgtctt tgtaagcagg cattttagac acccccaatt atgtcatttt aatattacaa
    10081 taattataac atgttagata tgctatctaa ataattgttt tattttcctc ttctttttat
    10141 ttcttgaagc ttgtaatatt tacacagttc taagaagtct tcttctagtg ctatagataa
    10201 gtctaatatc gtagatatac ctatatcttt gtactcttga ttttctagtt ttgatatata
    10261 acttctgtta cgtctcattt tttctgctaa ttctagttgt gtcattcttt tcttttttct
    10321 taattttttc aacatttatt aaaatccacc ttttaattat ttttatgaca tttttataat
    10381 taatagtttg tgtaatttct tgtaaaaaat gttcctcatt agaacatttt ttggtggaaa
    10441 aatgtgttaa aatgtaagta agaaaagcac tttcaaagca ctataaaaat agtgctgaaa
    10501 tagataaaca aataaaagta ataaggagga aagatagatt ctagagggaa atcattatca
    10561 tttttaagaa cgtatgttcg gttggtggga tagaaaaata ctttacaggg gatggtttat
    10621 ttgaatgaga atgaaaatat gagtttatat gtcagtaagt taaaagaagt attgaaaaat
    10681 aattcagaag agtataaaaa aataagagct aaaataaatg aaatttataa tctaaatgaa
    10741 aagaaagaat aaaagggctt tagctctttt attctttctt agtattaact gctttataat
    10801 aagcattatc tatcattttt tttattgcat ttttatcatc tgaatctaaa gatgctaatc
    10861 tatttattag ttcgttaact tcattatctt cttttgagtt aacttttttt aataattcat
    10921 catcttgttg agtgttaggt tgtattttac ctaatttagt taatagctcc tttaaagtta
    10981 aatttaatcc aaaactcatt ttttcaagca tatctaaagt aggttcaaca gctttaccat
    11041 tccttgggtc tctgtttttt tctatcttat ctatatatgt atggctcaca ccacaaagat
    11101 tagaaaattc tctaagagat aagttatgtt cacttctata ttctttaata atttctgcta
    11161 atgtttgcat aatttcacac ctcatctaag taatagttga cttaattata tcagaaaaat
    11221 gtaaactatt gttaacaaaa ataaaaattt agtaaaaaat aattgacaag agtaaaaaaa
    11281 agacgtatac tatgattaac aaaaaggtta taaataaagt taggagggat taatataaaa
    11341 aataatttac aatatattag aaaagaatct agaatatcac aaaaaaaatt cgctgataag
    11401 ataggtatat caagaccgta tttatctaga atagaaaacg gtaaggttaa tccgagttta
    11461 gaaatagcgc ataaaatctc gctcgaaaca gggaaaacaa taaatgaaat tttttttgat
    11521 tttactgtaa atcatagtaa actataaggt tttaattgta ccttgaaaac taaatataaa
    11581 atattttaaa ggagcaagta tatgaaaaat aaagaaaaag aaataatcat tagaggaatt
    11641 ttaataggaa ttttttattt tttaggaatt gtatttagta atactttttt taaataataa
    11701 atagaagggg taggtgaaat accaactccc caaatcaaaa taacactttg gaagttaaat
    11761 ataaaatatt caaaagaggt gattagatgc aaagagagca aacaacgctt cgtataccag
    11821 aagacttgca caaagcgttg atagatttaa gcagtgatat aggaatgcct attacatcta
    11881 ttataataat tgcatgttgg ttgtatatat caaagataaa ttaaccaatc cgatatgcaa
    11941 aatgaatgca caacattatt tattagagaa ttgattgata aattattttc tttagctgtt
    12001 ttctctagca actcttttag gacaccagga atcctaagag tagaacgaac agtatcatca
    12061 cttttatacg agattgattg aagttcatta acttttgaat ttctaataat atcattaata
    12121 gcgtatagaa taagcgaaga tttgagaatg cctgtttgat aagaaatttt ttctaaattt
    12181 tcatttaatg gtgtatatat tcttacagta atagtagtca ttttgacacc tccctaatga
    12241 cattatacaa aaaatattta aaaaagtctt gacactaaaa tagtgtcata atctaatgat
    12301 tatagacagt aaaacagtgt cataaggagg gaggaataag aatggaaaaa gtaagaatga
    12361 cagtaaggct cgtcccaaaa ttaaatcaat atgtacagaa tatagccaaa gaatgtggaa
    12421 aaagtaaaaa ttctattatt gtggatgcat gttgggagtt tattgagaaa ataaaaaaag
    12481 aaaataaatt caatgtagaa agcgaggaat aaatatgaat aatctacaga tatttgaaaa
    12541 attggaattt ggacaaataa gaatggcaga gattgataat aagccttact ttgtaggaaa
    12601 agatgttgca aagtcattag gttataaaaa tactaatgat gcaattttaa gacattgcaa
    12661 aggggtagtg aaacacgagg ggtttaaaat taatggtatt aagattgctt tgataactga
    12721 gggtgatgtt tatagattaa tagtaggttc aaatctacca aatgcagaaa agtttgagag
    12781 ttgggtgttt gatgaagtgc ttccaagcat aagagaaaca ggtcaatacc aagcacaaca
    12841 gcatgtaata acagaactta caggaactat aggagactta aaaggaacaa taaaagaata
    12901 taaaaagttg tgtaagataa catgctctaa gaaacaacag tattctaaat acataaagaa
    12961 tagactggat atagacaaag ctaataaaga atacaaccaa gtgaaagcaa ggctattcct
    13021 aattcttgga gttgagaagt gggaagacat agacttcgat acatctaata atttaataca
    13081 aattatagat gattgtataa gagttataaa gtcagagaga ccatacaagc agttgagtta
    13141 ttttgaaaac taaatacaga atattttgaa atatattgtt ttaattaatt attaactagg
    13201 aggttaaata catgaaaaat aatataagcg attcaagagt aaaatatttt tgcaagtgtc
    13261 catactgtgg gtttgataat gaggtagaag ttaaaaaagg attgaagcct aaaatatgtt
    13321 gcatatgtac aaaagaagtt gagtatgaaa aactggagca acaaagtact ccagcaaaat
    13381 aaaattaata aatatgaata tttttacaag aatctaattc tttttctaac ttattaacag
    13441 catggttata ttgcagtgcc tgttctgcta taaagttaga atttgatatg tgttctttac
    13501 acatagggca tggtagccca ttatcacaaa cttccctaaa tttagattct gttatggtaa
    13561 cttttgtacc acaatcgaaa caagtagctt caattttagt tattttaccg atattcataa
    13621 atcaccacct aatcatatat ttataggatt tatcctacaa atatagtata tcaaaggagg
    13681 gaaataatgg caattaatga caacataaat aaaattttaa gagatagaaa tttaaaagcg
    13741 tggaaattag caaaagaaat aggcgtagat tcaggaaatt tatatgcaat tttaagagga
    13801 gaaaataaaa atccaactat agatacattg ataaaactag ctgactattt agatgttaca
    13861 ttagacgaat tagttggaag atagaaatta aatacagaat attttgaaag taggtgtatt
    13921 gtatggcaaa agcagtagct aaagaacaat tgttttatag ggcaaaagat atagctaaga
    13981 ttttagatgt atgtgaagca accgcttata aaataattgg agaattaaat aaagaattag
    14041 aaaaagaagg ttggaagacc tttcctggaa gggtatcagt aacttatttc aaagaaagat
    14101 attgttataa aacaaaaaaa ggggcataaa aaatgctatg agagtagcta aagatatgtt
    14161 tcctaaagta attgtataaa gaggaagggg gtgatttagt tgaatgtaag agtactgata
    14221 gcttatatac agttttgtaa gcaatacaat aagaaagcga gttttgaagg tcttaaaaaa
    14281 tacaacaaag gggtaattgc atgagaataa tttataaaaa caaaatctac aaagtagaac
    14341 aagacaaagt gttatttaga attacatact atgatgagca gaaaaataac aggaagttta
    14401 ataacaataa gaaagtaaaa agaagtgttt taacaagaga tatagagtta gttaacttgt
    14461 atttaccagc acatttaaaa ataaagtagg aggtttaatt gcatatggta tttaatttag
    14521 agaagttcaa agtgggaaat gcgataagaa taagttgtga aagatttggt tttgaaattg
    14581 attgtattgt agtagtagca actgaggagg aactaaattt agcttacttt gataaagaaa
    14641 gaggttgcat agagtatcaa gcattgatgc cagaagacct tagatatgat gattatattc
    14701 tcgaaagatt aggttagagg gggtgtattt taatggaaac agctatatct attgcaaaag
    14761 gtcaaataga aggagcgaat gagagtataa aggaattaaa atcaaaagaa aattacgata
    14821 aagaaagttt aagatggtgg gaaggtgtta agcaagctag tgaaaatata ctagagtttt
    14881 tagaaataga aaataaggca taagaaaaga gccattacga ttggctcaat tcaaaaacat
    14941 aataaaattt aattagctat attatagcac aagggggaac taaaatgaaa gcaattttat
    15001 taaaaagttt aaatatagag aatttcaaag ggataaaaga acttcgcata gattttaaca
    15061 acataactaa tgtgtttgga gaaaatgcaa caggtaaaac aagtatattt gatgccttta
    15121 cgtgggtaat gtttgacaag gatagcaaga atagaagcgt atttgagata aagcctttag
    15181 acaagcaaaa taaagtcatt agaggacttg taacaactgt aacagcagtg ctggaagtta
    15241 ataataaaga gataaagtta acaaagaaat atgaagaaaa atggactaga aaaagaggag
    15301 aatcagaagc aacttttact aaaaacgaaa caacatacat gataaatgat actccaataa
    15361 aaaagagtga atatgtaaaa gaggtagctg aaatagcaaa cgaggaacag tttaaattac
    15421 ttactaatcc gtatttcttt tcgaatgagc ttaactggaa aaaaggtaga gaattaattc
    15481 taaatgtgtg tggagatata acgacagaac aaattataga atcaaataaa gatttaactt
    15541 tacttattac agagtttgaa aaggaaaata acatagataa gattattaaa aatagaaaag
    15601 ctattaaaaa taacttatct aaagaaaaag aagaaatacc agttcgtgta aatgagtgca
    15661 ataaaagcat gtatgacata gattttgagg aaatagaggc tcaattaaaa gctaaaaagg
    15721 ctgacttaga agctattgag gacatgttac taagtggcac aaaggcgaat gaacagattt
    15781 taaaagataa agaaaagata tttgagctaa aacaagagac acaaagtatt aaacaatcag
    15841 caagtgaaaa aggaaataag aaaaggaatg agctgttaaa agaaaaggat gagttgaaat
    15901 ataatattaa aaacttaaga aataatcttg tttatttaga aagggataat gagttaaaag
    15961 aaactttgaa aaaaagagcg attgaaaaaa caacaaattt aagagataaa tggactaaaa
    16021 agagtcagga aacattagat ttaagtgtta tccagacaga atgcccaact tgtaaaagac
    16081 ctcttgattt agaagatata gaagaaaaga aaaaggaaat gttagataat tttaatctaa
    16141 ataaagctaa agaattaaaa gaaatagcag agctagggaa atctaaaaat gatgatgtag
    16201 aattatttaa tacagaaatt gaaagattaa aagtagatat aaataagact ttagaagaga
    16261 tacaagaaaa agcagtatta ttagataaaa taaaaaaaga attagaaagt acaaaatcta
    16321 cagagatata ttcagcagat gaggaaaaaa gattaacaga aattagtgca gaaataaaag
    16381 agttagaaga aaaaataaac aataaagatg ctgataaaaa tatagatgag ctaaaagaaa
    16441 ataagaaaaa actgactagt gaaattgagt tacttaataa agaactagct aaaagagata
    16501 ttaacaaaga gttattggat agaaaagagc agttgttaga aaaagaaaaa gcgttaggta
    16561 tagaactagc tcatcaagag aaaatactca acttatgtga attatttata aaaactaaag
    16621 ttagtttatt agaaagtaat ataagtagta aatttaagaa tgtaacattt aaactattta
    16681 aagagcagat aaatggtggt atcgaagaaa cttgtgaagc tttaataaac ggtgtacctt
    16741 tcagcaatgc caacacagcg gggcaaataa acggagggct ggatataata aatactttat
    16801 ctaatcactt tgaagttaaa atgccaatat tcgtcgacaa cagggagagt gtgaataatt
    16861 tgattgatat tgatagccaa gtgataaatt tgattgtaag taatgataac ccattaaaaa
    16921 tagaaggggt gaactaaatg gcagaaagaa atataactga tgtagtttta aatagagtga
    16981 atgagctaaa agatagtggt gagttagtaa ttccacccac ttattcagca gtaaatgctt
    17041 taaaatctgc atacttaatt ttacaagaaa cacttgataa gagctataag cctgtacttg
    17101 aaacatgtac tcctattagt ataatcaatt ctcttttgaa catggtcata caaggattaa
    17161 gcccagctaa aaaacaatgt tactttgttg cttatgggaa caaattgcaa cttatgagaa
    17221 gttatatggg tactatagca gttactaaaa gactttctaa tataaaagat ataaaagcgt
    17281 attgcatcta tgagggtgat aaattcaaag tcaaatacaa taaagaaaat gctgtactag
    17341 aaataggaga atatgaacca gcttttgaaa acatagatat aggcaaaata aaaggtgctt
    17401 ttgctgtaat tgttggtaat gaaggaatct tgcataccga aataatgacc tttacacaaa
    17461 ttgaaagagc atggttacaa ggtgttggct atagtaatcc caaaaataaa gtacatgata
    17521 attttacaga agaaatggca aagaaaacag taataaatag agcgtgcaag atgtatgcaa
    17581 ataccagtga tgatagtgat ttattaatag gtgcttttaa tgaaactgat agagtaatca
    17641 ctagcgaaga aattgctaaa gatacagaca aagaagtaga aaaagagatt tctcaaaatg
    17701 ctaatatcaa gtctttagaa atgccttcac aagtggataa tacaatcttt actcaaacta
    17761 aagaaaaagt agctattaac atagatgaag ataagccgaa tctagctgaa tttgaagaag
    17821 caatccaagt tgaattggat acaccaccat tttaaatatg attaagatat tagggagcag
    17881 tagcagaggt aattgctact tgctccaact ggaaaacgag acattaattt tagagtgtgg
    17941 agtcagttac aaagagatat taaaaggctt agatttcagt ttagaaaatg ttgtaggatg
    18001 tttggtcaca catgaacata aagaccactc taaagctatc acagagctta caaataatgg
    18061 aatagatgta tattctagca agggtacatt agaagcttta aaaatagaaa atcatagaac
    18121 taagattata gaaagcgaga aattattcaa gataggtaac tttaagatag tgccatttaa
    18181 tactaagcat gatgcggtag agccattagg atttttaata aatcatagta gttttggtaa
    18241 cctattattt ataactgata gttattattg tgaatacaac tttaataatt taaatcacat
    18301 catgattgag tgtaactata gtaaagattt attagataac aacaaagata agatttattt
    18361 gagaaataga atagtcaaaa gtcattttga attaagtaat gtgattaatt ttctaaaagt
    18421 aaatgattta agtaatataa aaacaattac attgcttcat ctaagtgaag ataacagtga
    18481 taaagattta tttataagag agatagaaaa gaatgtggga gtaccagtaa tagtagctga
    18541 aaaaggatta gaaatttatt tagactagag gtgataaagt ggcaaaatat agaattttac
    18601 aagctaactt ttgggatgat ggatttgtat tagatttaac tcctgaagaa aagtactttt
    18661 ataactatct tttaactaat ggtagagcaa gtcaatgtgg gtgttatgaa ttaccctata
    18721 aaattatgga aatgcaaaca ggatataaca gggaaactgt agagaagtta attaaaaggt
    18781 ttatagagta tggaaaaata aaatatgact ctactactaa agagatatta ataattaatt
    18841 ggagtaaaca taatttttct aaaagtccaa aagtacgtac ttgtatctta aaagaggttg
    18901 aatcaattaa aaataaagaa tttcagcagt atatgtatag agtatgtata gactatggat
    18961 accctatcga tacagtatct atagactatg gggaaaaaga aaaagaaaaa caaaaagaaa
    19021 aagaaaaaca aaaagaaaaa gaaaaacaaa aagaaaaagt agaaccgtta atttgtgaag
    19081 aacaggaaaa aaatgagtta aaagaattta agaagctata tgaagaaaat ataggagtgg
    19141 tatatccagt tacagcagaa tggttaatag aaatttctag tgatgtagat ataagattat
    19201 ttaaatctgc tatagagata tgtgctgaaa agatgaatat gaatatagca tacttaaaag
    19261 gtatccttaa aaagtggaag gatgcgaata taactacata tgaacaacta gaatcatata
    19321 gattacagca agaaaataag aaagcaaaaa aagtagttaa tggccaacta agtaaaaata
    19381 agtttgccaa ctttgaacaa acatttacta agtatacaga gaatgagctt gataacataa
    19441 ttaagaaaag tcaagatgct aagttcaaat aaaattaaac ttctaggaag taaatatcaa
    19501 tatattgctt cctagaaagg gggtagaata tgggtaaaat ttggatggat gcaggaacat
    19561 ttttggaaac taaagatata ggagatattg aatgtaatct aagagaaatg ataaataaaa
    19621 ataaacaaaa aaatttaatt ggtagaataa attccaaagg acaaggaaga aaaagtaaga
    19681 aagtagagtg tactaacatc attactggag agagtaaaat atttgtcagt gctgtagaag
    19741 caagtgaata tttatatttc acggaacttc atattactcg tctagcaaga acaggaaaga
    19801 ctactaaaaa tggttggaaa gttagatata ttgaagaggt gtcaaatggt attagcaaat
    19861 gtggaacaag taattaagtt agctgaaaag atattaagta agaaaaagtg ttctgttaat
    19921 aaagctattg atatagctat aaaaatatta aatagatacg aatatgaggg gatgattaaa
    19981 tgagtctaat tgaatataga ggttatgatt ttgaaaataa aaagtggatt tattctaaaa
    20041 caataatgtg gagtaatgca gtagactgtt tattaatgct gaaagaagat tttaaatggc
    20101 gaaaagtttg taatgttgga atatgttctg aagaatgggc tggaaataat caagaaattt
    20161 ttgaagggga tatattaaaa gaaaattata atcctcacaa tagaagttca tatggaattg
    20221 taaaaagaga ttttaatagt attaagttat atttggagtg gcattattta aagaagtttg
    20281 aaggagaatg gatagagatt atagataaaa cagaaatata tcatagtaga ggttacaaag
    20341 taattggtaa tgaatatgag aacttagagg aagttaggaa agagttttta gaacgcaagg
    20401 agatgttgga aaatgaacgt cttagctagt ttaatactta tagtaggaag ttttatagct
    20461 ggtagggttt atgagtatag attgaatcta aaagagtttg aaaattatga taatatagga
    20521 ggttttaaga atgaatgata gattagaaat gataaatgct tctgtaaatt atatacagat
    20581 gatatgtgaa agttcaaata tagctattat agcagagcat gaccgagtta gaatattgga
    20641 tttagaaact aaagaaaagt atgacctatt aagaagtgag ggggattaaa aaatgagtaa
    20701 agttatacaa tgtgatttct gtaaggaaat atttgaaaaa tataatggag aatgtattga
    20761 gctatataaa aaggattgta gcaaaggggt gcttgggata gataaacaca tatgcccaac
    20821 ttgttatgaa aaattcattg aaggaaaaat agagaaagta gaaaatgcta aaagatttaa
    20881 ggataaatta atagacttct tggttgagca tgaggtttgt gactgttgtg cttgcgactg
    20941 tgtgtttgat tctaatgacg aaaaaaaatg caaggcagga attagagagt gggttgaaag
    21001 tgaggtagaa gaataatatg gcaaaattaa tagttagcat acctttaact aaatatttaa
    21061 aagatataac taaagaatgg ggagaaactt atataactaa aacatatggt gggcatgtct
    21121 atttaagtga tgaagctcca ggagaagtat ttaaaaaaga agatgattta aattatatag
    21181 agtttaacga ttctgatatt gtcatgagat tacctaaaga agtacatcaa catataaatt
    21241 tgaaaaaagg ttgcaacaag aatcttaaag atgtattaaa agaaataaaa aagatagaag
    21301 agaaaacaaa tatatagaaa atatctaatt aaaacagttt agagagttgc aaaatatctt
    21361 ttagtataaa tttattgttg aagtgttttg tgactctcaa aaatgaaaat aaggaggagc
    21421 tatattgctt acatttttag atttattcgc agggataggt ggttttaggc taggaatgga
    21481 aaaagcagga cataaatgtt tgggacattg cgaatatgat aaattcgcaa atttaagtta
    21541 taatgccatg cacaaaccga aggaggatga atggtttgaa agagatatta gagaaattag
    21601 aacagaaaat atcccaagag cagatgtctg gtgttttgga ttcccatgtc aagacatttc
    21661 tgttgcaggt aaacaatttg gatttaaagg aagacgttca agtttatttt tcgcagttac
    21721 aaaacttatt agagaactca aagaagaaga tagacccaag tatttactta ttgaaaacgt
    21781 taaaaatcta cttagtgtta atggaggatt tgatttcctc aaagttctca ttgaactgga
    21841 tgaaatcggc tatgatgcag agtggcaagt tcttaactct aaaaacttcg gagtacccca
    21901 aaatagagaa cgaatattcg ttgttggaca ttttagagga cgaagtacac gaaaagtatt
    21961 tcctatcgaa agaaaaagta gaaaaaatct tgaacaacta aataatccaa ctcatagtac
    22021 aagtggagtt ttagtcaatg cagttttaac acccgatagg gtaaacaaaa gacaaaatgg
    22081 tcgtagaatt aaagaaagcg gagaaccaat gttcacacta acagctcaag ataaacatgg
    22141 aattttgaaa aatggagata taagaaggtt aacaccaaag gaatgcttta ggttgcaagg
    22201 atttccggat aaatattacg aaagagcagc aagtgtatgc tcagatagtc aactgtacaa
    22261 acaagcggga aatgctgtta ctgcaaatgt tgtatatgaa atagcaaaaa gaatgggcta
    22321 agagttgcaa aatgtctttt agtatgagta ttgttgaagt gttttgtaac tctcaaaaat
    22381 gaaaataagg ggtgaataaa tgtcaaagta tgtgcttaga tggcaaaaag ggttattgtt
    22441 ggatgaacgt aagataaatt attcatgtgg aagtaaagaa atgctaaaac aaaaagcaga
    22501 attattagct aaagatgaca agatattgct tgtaacaata gataaagttg aagaagttat
    22561 aaaagatact agaagtcaaa aaatggctga atattattgt gatggaggaa ttgaaatatg
    22621 ataatacaca aatttataat acatgtttta gataagaata gcgatacacc aatactaaat
    22681 gattttgagg gtagggttag tcaagatatt gaagctttct ttcaaaagaa aataagcaaa
    22741 gtatcaagag ataatgacat cagaacagta gtatttaatg actatagtaa caatctaatt
    22801 aagaagtgtt gtgaacaaat tatttatgat gaaagttcat ttttaaataa ctctaaagag
    22861 attgcagctt atttatttga tgttatgaaa ttgaatgcta tattagaatc ttgcgactta
    22921 gcaatttgct tatactctca aaaagatgaa aagaaagttg ctatattaaa gcttgattac
    22981 aataattcgt atactcattc tattagcttt gaagaggata aatttaatat acagatgtct
    23041 aagaatgaaa ttaatataca agagactaag acggttaaaa ttgctgcttt ggttggattg
    23101 agtggaatga atgacgaata tcatctaaaa gtattggata aggatgcaga gaaggaagaa
    23161 gctaattcta agtttgttac agagtttcta aatgctacta aagtgaaaga tgacaagtat
    23221 aggactaaaa agtttaaaga tacagttgaa aattggataa ctaatgttct tggaaatgat
    23281 ataaaacaag ctgaggacat aagaagtata ttaaattata ctttgaaaga aaagcatgaa
    23341 attgatataa aagattttgt tgataaatca attaaagatg atgagttaaa aaatagtttt
    23401 aaagaacata tggaagaaaa gggtcttgat gaaagtttta gcatagataa aaaatgggtt
    23461 gaaaaaaagc ttaaaaagag aaatataaaa actgacaatg gttttgaaat aaaaggtaac
    23521 ttaactgatt ttgaggaccc aatgaaatat acagtaagac aaaatcaaaa tgggtctata
    23581 gatataatta ttaagaatgt taatttctat aatgaaaaat aagggggcta caatggaaaa
    23641 taaagataat tttgtattaa ataagcttgg accagcaagt aaagtaatga aaaaagttga
    23701 aatagatgaa aaagaaatta agagttatct aaaagaacta aaagaatgtg aagaagtaaa
    23761 agtttttatt attagaaaag atggaattga aattccaata gttttcaaag atggaaatat
    23821 gaacgaatgg ttaagaaaag aaattgagat aagttttgat agatttaagg atgaaattgc
    23881 tcaagttaaa aaagcattga ttaaagttac aggagagaat taagaagtta gaaggtgctc
    23941 atatgactaa taaagaaatg tgcaagtcaa ataatcttga tgaaagagaa gtgtgtaagg
    24001 aatttggaaa agagatttgt ggtagttgta taaatgatag ggtagattgc gaaagcaaag
    24061 attgtgatat agcatatgaa aattggctag agaagaatac agaaagataa ttataaaaat
    24121 aaagtcaagg taagtttgtg aatgaaacta gaatgttata gacttacttt gacttataaa
    24181 aaaggagtgt attaaatggc taatatatat tgcgaaaatt ataattgtaa aaactacttt
    24241 gaagatatgt gtatgcttga aagaattgaa attaataacc tgaaagtgtg tgaaagttac
    24301 attgaaggta aaaatgagct atataaatta gaaaacggat atactataca tcctaaagat
    24361 ttgaaaatgg tgaaaagtaa agattattct gttgaagtta ctcatattcc aactggtatt
    24421 acagtaaaat gccgttctac aaatagtatt ttaaaaaata aaaataagtg tttggaagtt
    24481 ctagaagaag aattaataaa aataaactct cacttagagc tagaagattt aaactaaata
    24541 ggaagtgagc ttatgaaacg aagaagatgc agttggtgtg gtaagctatt ttatcttaag
    24601 gaaaaatcta aggatgttta ttgttgtaaa gaatgtagga agaaggctaa gaaggtgaaa
    24661 aaatgaaagt ttttcttgta atagatggag agccagttgg caaggaaaga ccaagaatga
    24721 atacttacgc taaaaggacc tatacaccta ataagactaa gaattatgag gacctaataa
    24781 aatggctata tcaatctaaa gttaaatatt actttgaagg ttatataaaa atgactttaa
    24841 gatgttatta ttctatagct aaaagtaaca gtaaaaaggt taaggagcag aaaagaaata
    24901 atgtgttaag acctagtaaa aagcctgaca ttgataatgt cattaaagta gtagctgatt
    24961 cactcaatga gatagcttat aaggatgata cacagattgt tgaggttgta gctagtaaat
    25021 attacagtga taaaccaaga gttgaggtta tattagaaga tgttatttaa ccaacggaaa
    25081 aatccgttcg ttagattagg tactcagttt ttcataaaaa tgtgaaaaag ctgaatagag
    25141 aatatatcaa atggtaaagg agagataaat tatgaatgaa aatataaata aagaaataac
    25201 agtacttgga actttagaaa tcgagggaat gaaatttcat aacattgagg gtggatttgg
    25261 agaacataag aaagcaatgc tagtaaaaga tatagctgag atacataata gagaacttaa
    25321 acatataaat gagctaatta ataataatat aaagagattt aaaacaaata tagatattat
    25381 agatttaaaa gtgagtcgtt ctgagcgact aggtgattta aaggctaatc cttttgaagg
    25441 attaggttac gaggatgttg gatatagtaa acaatctttt aatcagtcaa gaaatattta
    25501 cttgttatct gaaagaggtt attcaaaact actaaagata ttagaagatg ataaggcttg
    25561 ggaacaatac gagaaaatag ttgatggata tttctctatg agaaaagagt taaataaccc
    25621 tcttttaagt gcatcgaagg agttacaggc tatatttatg ctagataaga aacaagaagt
    25681 cttagaaact aaaatagaga atgttaatga gaagttagag aactttatgg atgatgcacc
    25741 attattcaat atcgagtgtg agtgtattgt taaagaggtt aagagagtag caacaaaatc
    25801 acttggtgga catggaagta aggcttataa aaataaatct ttaagaggta aagtttatag
    25861 tgatatatac catcagatta aacgagaatt tggagtagat agttataagg ctataaagcg
    25921 ttgtcagtta gataaagtat tagagattgt aaataattat aagttaccta tagtgtttga
    25981 agaagaaata agacttttga atagtcaatt atcaattgtg agttaagaca ggaatagatt
    26041 tttctccttt aaaggggaaa acctgcaata gttaattaaa agagaaaagg agtgctttca
    26101 cactccactt gtcaaaaata taaaactttt atatacaaga ttattataac ataaataatt
    26161 gataggagtg tgtgagtatg tctaaaacta aaaaagagtt ttttaatgca actaagaaac
    26221 aactttctaa ttataaacaa ttaagtgcaa atataataaa attaaaaaat gaaatacaaa
    26281 tgttgaaaga taattcggtt ggagatttaa tgaaaggtat aagttatgat agtgtcaaaa
    26341 caggaaaaac aaacaaaact agtaacatga ttgaggatgc tattgttaat gtatcagact
    26401 taataacaga aaaggaaata gagttatatg aagcagaaat aattaaatcc acaatagatt
    26461 tagctataag aaacttaaaa cctatacaca gacaaattat tgaacttaaa tatatagatg
    26521 gtctaatgtg gcaagaaatg gttgatatag tacatttaga agaaagacaa ttaagtgtaa
    26581 gagctagtca agctattagc tcaatatcaa tagcattatt tgggaagaaa gcattaatag
    26641 agcaagaacc actttttgaa ttgttagatt acaaactaaa ttaaaaaagt aagagtaatt
    26701 ttgagtgctg aaaatgtgca ggtttttttg ttttagacat gagataatag tattgtggaa
    26761 atgaatattt ctctctcaaa actaaatata tatgtgggct aggtaaaggg attcacctag
    26821 cttatatgaa cagactaggc agggcgtgag gacgctgtta gttcaattct aactatgttc
    26881 aatctttagt ttttctattt caattaatct acggatacac taaaaaatag tatttgaatt
    26941 gagattaaaa tctcatacag ttttgtatct taattcagag tctaaaccga gtggggcttg
    27001 gtaacctcac tcaccatgca ggtactggtg tttaatctaa gttcgattct tagaacttgc
    27061 gacataatat atgtatctcc ctatttaaaa aggctaagtg agggtaagct tagtctttta
    27121 atttaaaaaa aaaagaaatt tttattgtca taatactatt tgcttaggta tattataatg
    27181 tgcatactta aaattaaata cttagcaagc atttgaatta atatacataa aatatatgac
    27241 ataatttttt atagtgtaag ttatttaaat taatataaat aacagtaatt ttattataga
    27301 aaatgtatat attgtgaata ataataataa taaaatcttg tacaaaatgc caactgataa
    27361 ttcctcgaaa tgtattgtgt atttaacgtt acgattgtat aattaactta taatagtgat
    27421 atggaaggtg gtacttatgg ctacaaaaag tattttaaaa aatgtagatg taagaaaaaa
    27481 ggcatttgga agaaatctag tatcagctct agaaaatgct aaaaataaac aagaaaaaga
    27541 agttgtatta agtaaaaaat gttcagaagt accaaaagat aaaataaagg atatattcgg
    27601 gagattttaa tgagtggcta tttaattgta aacttaagta atatgctggg agaactggag
    27661 gaagaagaag ttaaaaaaat tctctccagt ttttcttgtc ctcttaataa agatgtagaa
    27721 gactttttaa aaaacaaagc tattgaattt tctaaacagg gtttagctag tacacattta
    27781 gtattaactt cttataaagg caagcctgtt atagttggat atttcactct agctaataag
    27841 tattttacaa taaaaagaaa aacattaaca aactctttag ctagaaaagt agtaaagttt
    27901 ggacaatata atgaagaact aagaagatat attattggag cacctttgat aggacaaata
    27961 ggaaaaaatt attcaaataa ttataataaa ttaattaaag gtgatgaact tctaaaaatt
    28021 gcatgtgaca agataaaagc agtgcagtta gatatgggtg ggaaaatagt atatcttgaa
    28081 tgtgaagaca aacctaagtt aattgaattt tataaggata atggatttgt agattttggt
    28141 aaaagaagtc ttgataaaga tgaaacagat tcattggatg gggactatct agtccaaatg
    28201 ttaaaatatc taaaaaaata aaagtacata aaatctaaaa tgactatctt gatggatggt
    28261 ctttttttat acaataaatt aaaaggagaa ttatagaatg aaaaagataa ctaaacttat
    28321 attatgttct ttgctagtaa tcagtatagc gagtccatta caagttgaag ctaaaactac
    28381 tcatcattcc agttcgcatg tttctattca taagagtagt acaaaatcta aaagtagtag
    28441 acctaaaatt actaaaacta aaaaagctac taaaacatat agaactaaca aatctatcaa
    28501 aaagaaaata aaacttaaaa aacaagtaaa caaaaaaact caagttccaa ataaacaagc
    28561 tgctagaaaa gacaaaaaaa caactacata taattattac aatagctata actcaaatag
    28621 atactatact acttcaagta gcgggttaag tttctgggat tgctatatgt taggtcattt
    28681 attcaataac aacaataaag tttcagagca agatatagct agagagttgc aaaaacaagg
    28741 ttatagtaaa caggaaactg ataatatatt aagaaaagca aatcaaaatc aagctaaaaa
    28801 agaagaaaag aaaaaaagag tgatgatgtt aatattctct gtattaggag cattgttcat
    28861 tataggttta gggctaataa tatttatcaa aagggaatca aaaggttgca ataaatcaat
    28921 gtaatttaat tagatacata gactctaaca agagttcttt tttattccca aaacgacaaa
    28981 caaacgaggt ggtggtatga atgaaaaggc agatttagcc catgaagatt acttaaaagg
    29041 gcttaagtac aaggaaatag ctgaaaagca taatgtaagt ttatcgactg taaaatcatg
    29101 ggcaactaga tactggaaac aaaaaggttg caaccaatca aaaaaagttg caaccaaaaa
    29161 gagaggtgca cccataggta ataaaaatgc tactggtcca ccaggtaata aaaatgctga
    29221 aaagtttggt ttcttctcaa agtatctacc tgaagaaact agggaattga tgcaagaaat
    29281 atctataaaa gataaattcg atattctttg ggaacagata acaattcaat atgcagcaat
    29341 aataagagca caaaagataa tgtatgttaa agacaaggaa gaaatgatta aagaattaaa
    29401 gaaacatgaa agtacagaaa atggagagaa gatagagtat gaatttcaat ttgcatggga
    29461 taggcaagca tcttttctta atgcacagag tagagctatg agtgaattaa gaagtttaat
    29521 taaacagtat gatgaaatga ttcataagga ttggaatttg gctacagagg agcagaaaac
    29581 aagagttgag aagttgaaat gtgaagttga taacctaagt aaagatgaca ttggagatga
    29641 tgagttgaaa ataagtgtag attatggtga tagaaatgat agttagagta aattttaatc
    29701 cagatttcaa ggaagccaat tttactaaaa aaagatacag agcaatgaaa ggttcagcag
    29761 ggagtggaaa atctgttaat gtagcacaag actatatact aaagttagga gataagaagt
    29821 atcaaggagc taatctatta gtagttagaa agtcagaagc tacacataag tattcaacgt
    29881 atgcagagct tacaggagct ataaatcgta tttatggtaa acaagctgat aagtattgga
    29941 aaactacttt aaatccttta gaaattaaga gtaaagttac tggtaactct ataattttca
    30001 gaggagttaa tgatgcaaaa caaagagaaa aattaaaatc aattaacttc tcgaaaggaa
    30061 aattaacatg ggtttggtgt gaagaagcta cagaacttat ggaaagtgac atagatatac
    30121 tagacgaccg tttaagaggt attttaacta atcctaacct atactatcaa atgacattta
    30181 catttaatcc agtctcatct actcattgga taaaaagaaa gtattttgac tataaaaatg
    30241 atgatatatt tactcatcat agtacttatc tacaaaatag attcatagat gaggcttact
    30301 acagaagaat gcaaatgaga aaagagcaag accccgaagg gtacaaagtc tatggtcttg
    30361 gagaatgggg agaaactggt ggagcaatac ttaaaaacta tgttatacat gaatttccta
    30421 cggaatttga atactttgat aatatgagac tgtcacaaga ctttggcttt aatcatgcaa
    30481 atgtagtact cagaattggt tttaaggatg gagagttata tatatgtaat gaaatatatg
    30541 tacatgaaat ggatacatct gaaataataa agattgcaaa cagtaaaggt ttagaaaaga
    30601 atatatttat gtactgtgat agtgctgaac cagatagaat taagatgtgg aagagtgcag
    30661 gatataaagc taaaggagtt aaaaaaggac caggaagtgt taaagctcaa atagattatt
    30721 tgaaacaatt aagaatacat gtacatccta gttgcactaa taccataaaa gaaatacaac
    30781 aatggaaatg gaaacaagat gaaagaactg gattatatct tgatgaacca gttgagttta
    30841 tggatgatgc aatggctgct cttagatatt ctatagataa taagcttaaa aataatggaa
    30901 taagcttctt aaagtaaagg aggcgttaaa tatttatata agtgaaacag atttaataaa
    30961 agttcagtta aaaaaagaga gcacatttaa cctagtaaaa gttatagagc attatatttt
    31021 aaaacataga ccagagaaat ataaacaagg tgaagaatac tattatggca atgcagatat
    31081 aaacaataag agaagatatt atctcttaga tggagctaag gttgatgatt ttactaaagt
    31141 taataataaa gcaattaaca actaccataa gcttttagtt gaccaaaagg taggctatag
    31201 tgtcggaaat cccatagtat ttaatgcaga tgatgataat ctcactaagc ttttaaatga
    31261 cttactagga gaagagtttg acgatacaat aacagaacta tatctcaatg ctagtaataa
    31321 aggggttgaa tggttacatc catatattaa tagaaaaggt gagtttaaat atgtaataat
    31381 tccagctgaa gaagcaattc ctatttggga tagtaaaaga cagagggaat tagttgcatt
    31441 tattaggttt tattatattg aagatataga tggaaataaa ataaaaagag ttgagtacta
    31501 cacagaaaat gacgtaactt actttattga aagaggtaat agttttattc aagaattttt
    31561 atatgatgaa tatggaaaaa tgactgatat acaagaaggt cattttagaa taaataacaa
    31621 agaacaggga tggggtaaag ttccatttat accttttaaa aataatgaaa agtgtgtctc
    31681 agatttaact ttctataaat cattaataga tatatatgac aataatattt ctacactagc
    31741 agataactta gatgaaatac aagaggttat ttatgtatta aaagaatatc caggaacaag
    31801 tctacaagag tttatagata atataagata ctataaatca attaaagtag atggtggagg
    31861 tggagttgat aaactagaga taaatatacc agttgaagct aaaaaggagc ttcttgatag
    31921 attggaaaag aatataatta tctttggtca aggagttaat ccagaatctc aaaacacagg
    31981 tgacaaatcg ggtgtagcac ttaaattttt atattcacta cttgacttaa aatgttctaa
    32041 gactgaaaag aagtttaaaa aagcaattag agagctttta tggtttgtgt gtgagtattt
    32101 aaagataagt ggtaataaga gctatgatta taaaacagtt caaattactt ttaatcactc
    32161 tatgataata aatgaagctg aaaagataga tatggcagct aaatcaactg gaattgtatc
    32221 agatgaaact attgtttcta accatccttg ggtcgaggat gttaatgacg aacttgagag
    32281 acttaaaaaa caggaagata ctcaaaaaga gtatgatgat ttaattccta ataatcaaga
    32341 tggtgttata gatgaaacat aaagattatt ggaggaagag atttgaacaa ttagaagaag
    32401 ctcagaataa taaaagtata aaatattatc ttgaattaga aaaacaatat aaactagcaa
    32461 tgtctaatat agaaaaagat atacttatat ggtataacag attcactgaa aatgagggaa
    32521 tatctttatt ggaagctaag aaactgctaa atacaagaga actagaagag tttaaatgga
    32581 gtgtagaaga atatattaaa tatggtaaag aaaatgctat aaatcaaaag tggatgaaag
    32641 agttagaaaa tgctagtgca agagttcata taacaaggct tgaagcttta aaactgcaaa
    32701 tacagcaaca agtagaagtt ttatatggaa atgaacttga tggtattgat aaactaatga
    32761 gagatattta tacaagtgga tactatcata cagcttttaa tgttcaacaa ggagtaaacg
    32821 ttggttggag tttaatgagt cttgatacta acagaataaa taaagttatt tctaagcctt
    32881 ggactagtga tggattaaac tttagtgaaa gaatttgggg taagcataga cctgctttaa
    32941 tcaatgagtt acatactaag ctaactcaat caattattag aggtgaaaat ccaaaagttt
    33001 tggtaaatga attttctaag aagtttaatg tatctaaatc acaagctaag aatttaataa
    33061 tgactgaatc agctttcttt gcatcagctt caagaaaaga ttgttttaat gatttagatg
    33121 tagaaaagta tgagattatt gccacactag atttaaaaac atcaaatata tgcagagagt
    33181 tagatggaaa agtatttgat atgaaagatt atcaagttgg aataacagct ccaccatttc
    33241 attgtcattg caggacaaca acagctcctt ggttcgagga tgaagaaggt tatagagcag
    33301 caagagatga aaatgggaaa acatattatg tgccatctgg tatgaaatat aaagaatggt
    33361 atgaaaagac atttataact gataaaaaag atgatatact aagtaataag agttggttaa
    33421 aagcagattt cccaactgaa aagaaattta aaaagcatgt agaaaaacac ttaaatgaat
    33481 atggaaatat aactgctgaa gaatatttat ctactgcaag aaatttgtta tcagagcaat
    33541 taagtaatga tgtagaagga tttttaagta aagataactt tttatttaaa tatagaaaga
    33601 gtactaatga ttttgctgtt ggaagagctg atggtaaaat atcaacctta tttaagccaa
    33661 aagaaggtta taattactgg ctagaacaaa taaaagaata taaggaggtt tagacatgaa
    33721 ttgtccagta tgtggtaaag atgtagatgt atttgatatt tgtgataatt gtaattggca
    33781 aaacagtgga ccaaaagaaa ctaattacaa aggaccaaat aaaatgtcat taaaagaagc
    33841 taaagaggct tatgaaaaag gtaaaaaagt aatataaaag cacttgctaa gttataaatt
    33901 agtaggtgct tttattatgt aaaaatttat tgcgagggtg atttgaaatg cttaaattat
    33961 atctatactt attttatcaa taattgtgtt ttgtacaggg ctttatttat tcaacatgaa
    34021 ggttgatagt aatgaggaat taattgaatt acttaaaagt aagaatatca gaagaagaaa
    34081 aaaatataat tttattttcc cagcgttatt tccactgctt aattttattt taggtgtgat
    34141 actgatacta ttttttttac tagttagcaa tgaagatatg attaaaaatt taaaggggga
    34201 taaataatat ggctaaattt aaaaagaaat cagaggaagt agaagctttt aaatggatat
    34261 taggaagtcc taatactcct atatggtttt atcaagcttt tgagaaggga actatatggc
    34321 ttgatgaatc tttaaactct gtgaatcgta aaggtgaagt aaagaaaact atctgtataa
    34381 aatataaaaa tggagttatt agggcaacta atggagattg gattataaaa gatagtgaag
    34441 gtaaaattta ttcttgtaca tgtgatgaat ttgaaaagta ctataaggat ttggataatg
    34501 aaacaaagat ttctaatgga ggattggaat gtttaagaga gatagcatta aaagatgtga
    34561 attttaaatt tgaactcaca ggaattaagg aggaaaaata aatgttttat ctgttgttac
    34621 aagtaataag tatatgttta agtattacag tatttatgta tgttacaggt aatatagtct
    34681 ttaaaatcta tcttaaaagt ttaagaaaag aatatgagtc taatatacac gaagtttctg
    34741 atgaaatttt aaagagaata agaaaagaat taaataaatc attagatgaa agtctttaag
    34801 aagtttttta ttaggtagaa aacaaaagga ggtttctgtt attgaaagaa tatatgattt
    34861 ggtttaaaag cggcaatagc atatctggaa tagtagacga agatgttgct gataagttaa
    34921 tgcaagattt tatggaagct gactcagatt gtaaggactt gaaagtatat ttagatgaag
    34981 atggaacaac agtaatagat ttatcacaaa tagaagctat atcaataaat aattgtaatg
    35041 agaataataa tattggtttt agtaagtcct agatagggct tttttatttt gtaaaaaatg
    35101 aaaggagata tttaaaatgg attggttaaa agaattgcta gaaggaataa aagtagagga
    35161 taacaaaatt gatgtagctt ctcttcaaaa atctatagaa aagaaaataa aagagactac
    35221 aattactaaa gaagattata caaatcttga aacacaactt aatacagcta atgaaactat
    35281 taaaaagttt gaaggaggta tgacaaaaga agatgtagag aatctaaaaa caacttatga
    35341 aactgataag aaaactttgg aagaaaccta caaaaaagaa attgaagaaa aggactttaa
    35401 ttactggtta aatgatgctt ttaagtctat taaatgtagg gatgaaatag cgttaaaagc
    35461 tcatttagat atagaagcac taagaaatag taaagataga caaaaagctt ttgaagagca
    35521 aataaaccct ttgaaacagg ataaagatta tttgtttaat gcaacactag aaggtgaaga
    35581 gcctaaaata gatactataa caccagggca agagcctaag ataaatgatt ttggttttaa
    35641 ttttactggg gtaagacctc atgaaaataa taataaatag gaggaaataa aatggcagca
    35701 ctaaattatg caaaagaata ttcaaatgtt ttagcacaag catatcctta tactttaaac
    35761 ttcggggatt tgtatgcaac accaaataat ggaagatata gatggactgg ttctaaaaca
    35821 atagaaatac caactatatc tacaactgga agagtagatt caaacagaga tacaatagca
    35881 gtagctcaaa gaaactatga taatgcttgg gaacctaagg tattaactaa tcaaaggaaa
    35941 tggtcaacgt tggttcatcc agcagatata aaccaaacta attatgtggc ttcaataggc
    36001 aatataacaa aagtatataa tgaggaacaa aagtttccag agatggatgc ttactgtata
    36061 tctaaaatat atgctgattg gaccgcatta ggtaacacag cagatacaac tgttcttaca
    36121 acaacaaacg tattagaagt atttgataag ttaatggaaa aaatgacaga agctagagta
    36181 cctgaaaatg gaagaatatt gtatgttact ccagtagtaa atacacttat caaaaatgca
    36241 aaagagatac aaagaacagt aaacataaaa gatggtggaa cttctttaaa tagacaaacc
    36301 acagatattg atacagttaa aataattaaa gttccatcta acctcatgaa aactgcatat
    36361 gattttacaa ctggatggaa agtaggagca ggagctaaac aaatctttat gtccttagtt
    36421 cacccaagtg caataattac acctgtttct tatcagttct ctaagttaga cgaaccaaca
    36481 gcagttacag aaggaaaata cttctacttt gaagaaagtt ttgaggatgt atttatatta
    36541 aataaaaaag ctgatgcaat acaatttgtt gttgaaggag ctggagcata atggcacaag
    36601 taagaaaatt aaatagaata ttaactatag aagaatgtaa aatagatgat ttcttagaga
    36661 tgggatatga tttgatagat gaaactggta aggcagtaaa gtatggcaag tcattaaatg
    36721 taaaagattt aatagctgaa aataatattt taaggtcaaa agtcgagtct ttagaagaag
    36781 aaaataagca gcttaaagag aaaaataagc ttactaaaaa gtaggtgaaa attgtggaaa
    36841 ataatatgat tgatgatata gaaagaagac ttcaaggatt tggatatgtt ctaaaggatg
    36901 gagataaatg gttaatagat tttgtaagag aaaaaataga aaatattatt aaactagatt
    36961 gtaatataag tgaaattcca aaagagttac acaatataga aatagatatg atagctggag
    37021 agttcttatt taccaagaaa aatatggggc aattagatat agaaagtatt aactttgaag
    37081 ctgtagaaaa gtctatatca gaaggtgata caaaggtaga ttttgctata ggaagtggct
    37141 ctcaaacacc agaacaacgc tttgatagct tagtagctta tcttactact tatggtaaga
    37201 ataatatatt aacctttagg tgcttaagat ggtaagtaaa actagaaaag caatagaaat
    37261 gttatataga gataaatgta ctatagttga gtatcagcca attaaagacc ctgtaacaaa
    37321 acgaactaac aataaagaag tgattgtatt agaaaatcaa ccatgtaaac tttcatataa
    37381 aaatatagtt tctgctacag aagggaaagt agctaagcta gagcaaacta ttaaactctt
    37441 tatatctcca gatatagaaa ttaaagcagg ttcaaaactt attataaatg ataaagagta
    37501 tgtaagaagt ggagaatcag ctatatatcc aaatcatcaa gaaataatac ttgagttatt
    37561 taaggataaa gcataatggc tagatggggc agtgttgatt ttagagagtt taaaagagtt
    37621 tgtaaaaaga tggagaagct tacaaagatt gatttagata agttttgcaa agatgcagca
    37681 agagaattag cagcaagact cttaggaaaa gtaattagaa ggacaccagt tgatacagga
    37741 ttcttaagac aaggatggaa tggagtggct tatgctaggt cgcttcctgt gtataaacaa
    37801 ggaaataatt atattataga ggttgttaat ccgactgaat atgcaagtta tgtaaatttc
    37861 gggcatagaa ctaaagatgg aaaaggttgg gttaaaggac aacatttctt aacaatttca
    37921 gagatggaac tacaaagcca agttgataag attatagaga aaaagttatt aatattactt
    37981 aaaggagtat ttgatgctta ataatattat agatggaata tcagtaaagt tagataaatc
    38041 atttggagaa aaatatacaa tttatagtga ggatgtagag caaggtatta atgaaccttg
    38101 tttttttatt gttcctttaa atccaagcaa gacaccatat ccaagcggga gagaattaaa
    38161 gaaaaattct tttgatgtac attatttccc tcgttcagaa gctaagaatt ttgaaataaa
    38221 tgagatagct gagatgctac tggaggaatt agagtatata gaaattgatg gagatttagt
    38281 cagaggtaca aatatgaatt ttgaaattat agacaatgtt cttcacttct ttgttgatta
    38341 taactatttt actataaaaa ataatgatac caataagatg gatacagtag agttattcgg
    38401 tggtttgaag agaggtgata attttgaata aaacattaag caaagaagat gactacaagt
    38461 ttactaagga gcaaatagtt aattctaaga agtatgtaaa tagaaaagac ttattaaatg
    38521 caattttaaa agaaaatgag ttatattcct tctcagaggt agaggaaata ataaataaat
    38581 ttatgaaagg agtgagctag atggcgttag gtggaggaac atttgtaaca cagaataaaa
    38641 tattaccagg tagctatata aattttatct cagctaagag ggcaaccagt tcattatcgg
    38701 atagaggtat tgttgcaata cctttagagt tagattgggg catagatgaa gacgtatttc
    38761 aagtaaccag tgatgatttt gagaagtatt cagtgaagta tttcggatat gattatactc
    38821 atgagaagct gaaaggtttg agagatttat tcaaaaatat aaggttggga tatttttata
    38881 aattaaataa aggcgttaaa gccagttgta ctatagccac agcaaaatat agtggtatca
    38941 gaggaaatga cttaaaagta acagttacaa caaatataga tgataatgct aagtttgatg
    39001 ttgtaacact tttagataat aagaaggtag atactcaaat agctaaagtg attacagact
    39061 tacaagataa tgactatatc acttggaaga aggatgcaac actagaagca agtgcagggc
    39121 tggtatttac tggtggaact aatggcgaag ctgtgacagg agcagagtac caagctttct
    39181 tggataaaat agaaagctat agctttaatg ctttaggatg tttggctaca acaacagaga
    39241 ttaaaagttt atttgtagaa tttacaaaga gaatgagaga taaggtagga gcaaagtttc
    39301 aaacagtact atataagaaa agtgatgcag attatgaagg tgtagtgtct gtagaaaata
    39361 agattaaaga taaagattta gttgaatcta gcttgattta ttgggctact ggagctatag
    39421 caggatgcga tataaataaa tctaatacta ataaaaagta tgatggtgag tttgatgttg
    39481 gtgtaaatta cactcaaata caacttgaag aagcactaaa gagtggtaaa tttatatttc
    39541 ataaagttgg tgatgaagtt catgtgttag aggacataaa tacttttgta tcatttacag
    39601 atgataaaaa tgacgatttt tcaagtaacc aaagtgttag agtacttgac caaattgcta
    39661 atgatatagc gactttattt aatacaaagt acttgggtga agtaccaaat gataaatctg
    39721 gtcgtatctc gttttggaat gatgtagtta agcatcatga acaactgcaa aatatgagag
    39781 caatagaaga tttcaaagct gatgatgttt ctgtagaacc tggaagcgac aagaagactg
    39841 ttgtagtaag tgatgctgta aaagttatta gtgctatgag taagctttat atgactgttt
    39901 cagttagtta acaataagaa aggagaataa taatggcaca acaaataaaa gcaagagata
    39961 caataagtgc atctaaggca gagtgttttg taactataaa aggtaaaaga tataatttta
    40021 tgcaagctat taacttagaa gctaaaatgg aaaagaataa gagtgagata cctatattag
    40081 gtagtactac aaaaggaaat aaatcaacag gaagtaaata ttcaggaaat gcaacatttt
    40141 attataatac ctctatattt agagaattgt tgtatgagta taaagaaact ggtgaggata
    40201 tttacttcga tatacaaatt accaatgaag acccaacaag ttcagtgggt cgtcaaacta
    40261 taatactgga agattgcaat atggactcag gcataattgc taaatttgat gctgatgggg
    40321 agtatttaga tgaagatatg gattttactt ttgagaattg gaaattagtt gagaaattta
    40381 atatagcaaa tggtatggag taaaatacac atttatgatt tatgtatgtg tattttttat
    40441 ttataagaat aggagatgat taaaattaag gataaatatg agataaaaga ttcaatttct
    40501 tttgattata gcaataaaag acctttggaa gaacgtgtca gcgagatgta taaaaaggca
    40561 ggaaaatatc ttatagatat ttcagataag ttagcaacag atacaattga tggttcgtca
    40621 ttaaagccaa taatcataaa atttgaaata aatgaagctg gtgttgcaac aatagaaaaa
    40681 caaacaaaat atttggtgat ggaggtagaa taagaatatg ggagatttaa acgctttttt
    40741 aagtcaaaat gcaataaaag tagagaatag aaagtatgtg gcaagtgaaa ggtttatagg
    40801 agaagatgga aaagcaatcg aatgggaact taaagcaata gattcagata gggacagaca
    40861 attaagaaaa gattcaacta taagagtacc tatattaaat aaaaaaggga aagctacagg
    40921 acaatacact agtgaaacag attttaatac ttacactttg aaattatgtg tggaaactat
    40981 agtatttccg gatttacatg atgcagaatt acaaaatagt tatggtgtaa tgggtgcaga
    41041 ggagttatta acaacaatgt tgactcctgg cgaatataca gacctttcaa gtgaggtagg
    41101 agaggtaaat ggttttgata gaacttttga agataaagta gaagaagcaa aaaactaatt
    41161 tatgaaggtg attatgattc taatatagct cattattgcc ttcataagtt taaatggaaa
    41221 ccgcatgaat atatggattt accagttgat gaaaaagcat ttgttgctgc ttctatagat
    41281 atcaaagtag aagaagaaaa agaagaagct aaaaaagctg acaaagatgc aaagagaggt
    41341 agaagaagat aatctctggt gtaaaaattt tactaatata gtataatata tttaaaaatt
    41401 gtactggggg attaaataaa tgggattgtt tagtaaaaag aataagaaac cttgttgtat
    41461 ttgcggaagc gaaaaaggac ttatgccatc tatagaaggt gaaaattttt gtacagcttg
    41521 taattgcaag tacatagatt tctctgaaaa tattttaaaa gtaactagta ttatgaaaat
    41581 gatgtcaaac tcagaaggaa tgaaaaagtt tatagaagtt gaaaagaaaa atttaaaatt
    41641 gttagagaag ttcaccgaga caaaaagtat aaattcttca atttcttttg atgaagagca
    41701 aaatctttta aaaatatcat ataaaaatag aaatcaaata ttagtagaga aaataataaa
    41761 atttgatgat atattagaat ttgaactttt ggaagatgga gaaactatag ttaaaggtgg
    41821 tttaggtcgt gctataactg gaggagtctt attcggaggt acaggggctg tagttggagg
    41881 aattacaggt aaaaaaacaa gtagaaaagt tgtagaaata tttaaaataa aaataactgt
    41941 aaaggacata aataatccaa ttgaatatat aaatttaatt aatagtaaag taaaaacaaa
    42001 ctcttctatt tatcagaaag ctttttctga tgctcaagaa atattatcaa tactatcaat
    42061 aattacaaaa tataatgtaa tggaagacaa aaaaaagtct atatctagtt ctacagctga
    42121 tgaaatatta aaatataaga atttgttaga tatggaagct attacacaag aagaatttga
    42181 tgctaagaaa aaagaattgc taaatttata atatataagc acttacttaa aaataagtaa
    42241 gtgcttatat tatgttaaaa aagaaaggag gttaaaaatg gcaactatac aaacatctat
    42301 ccgaattttc gacggaatga cacctgcttt tagacacatg aataatgcta tgaatattgt
    42361 attaagttca ttcgagcaat tacaaagaac atctagcaat gctatagatg ctaatagtat
    42421 tagaacagct agagaagaac tagcacgtgc agaagctggc tttgatagac tagaacaaca
    42481 aataagagaa tcagataatc aacagcgaag gcttaatgag gatataaata agggtgcaag
    42541 ttctacagat agattagttg gaagtgcaaa gaagctagca gcaacctact taggtataag
    42601 aacgttagga ggtctaggaa atttaagcga ccagatgaca agtactaacg cgagacttag
    42661 tatgataaat gatggtcaac tctcagatgg aggattaaat aagatgattt tccaatctgc
    42721 tgaaaggtct cgtgcatctt acttagatac tgcaaaaata gtttcacgaa taggcatgaa
    42781 cgcaggtaag gcgtttagca gtacaaaaga aattgtaggt tttgcagagc aactaaataa
    42841 aaagttcgta attgctggag caagtactga ggaaatgaat tcggcattgt tacagctaac
    42901 ccaagggttg agttctggtg tattaagagg tgaggaactg aatgctgtgt ttgagtcagc
    42961 acctaacatc atccaatcga ttgcagatta tttggacgtg gacataggaa aaataagagg
    43021 aatggcatca gagggaatgt taacagcaga tattgtaaaa aactcattac ttgcagcagc
    43081 agagcagact aatgcagagt tcgagaagat gccttatacg ctaggtcaaa tctttactag
    43141 tgtaaaaaat aatgcagtta tggtatttgg agctatacag aagaaaattg aggacacagt
    43201 ttcaagcagg ggatttcgaa ctttcataac tgatgttaaa gactcattat atgtacttgg
    43261 agcagttggg tttaatgtat ttagtggatt tattaattta ctgagtagtc cagcttttca
    43321 gaattttttt aatgtgatga ttgttggaac tagtttagtt gtacaagggc taggttggat
    43381 aataacacaa gcacttagtg ttgctaatgt attttcgcga aattggagta taatttcacc
    43441 tataatttta ggtgtagttt cagctattag tacctatata atagctcttg gtattatgca
    43501 agcagttact atagctggaa ctgtagcaaa ttggatgtcg tggacatctg aagttattag
    43561 acaaagagga attttaggaa cagctagagc tttagcgata ggcaaagctg aacaatgggg
    43621 atttaatgct gctatatatg catgtcccat tttttggata gttttaggta taattgcagt
    43681 aatatctgct gtatttatat tagtagcagt ttacaatcac tttgcaggca caagtatttc
    43741 tgcaatcagt cttatagttg gagcttggta ttggttatgt gcagttgttt acaacgtaat
    43801 tgtagggata gtaaatgcta taaatatctg tgtggttgaa atagcaaata tctttagaac
    43861 tggattatat gcagtgcaat gtttctttat tgatatggct aatgcaggac tcaaggcagg
    43921 tgttaattta gacaaagctt ttgataaatt tgctaccaat ctagcaaatg gtattataaa
    43981 agctgttaat atagctgtaa aaggattgaa ttggttagta caacagatta ataaaattcc
    44041 aggaattgat ttaccacaaa tgaaagaatt tcaaaaagta aatactgtaa ttggtacaaa
    44101 aacaacattt aaacccattc aaaaaccgcc tgagcctaaa gcatggaaac cagaattagt
    44161 agagtacaaa aatttaaagt cagaatttat aaaaggatat gacgtaggac atcaattaca
    44221 aaacaaattt aaagatactt ttgacattag caagatagcc gaaaaagcaa aaaaagattt
    44281 aggtctagat gacctttggg ataaaaaata cggacttggt gatggattgg gttcagctgg
    44341 attaaattca cctttgagtg acgcagcaaa aggagcaaag gacacagcag gcaatactgc
    44401 aaaaatggca aagactatgg ataaaagtca agaggactta aaatatctta gagacattgc
    44461 agagcaagaa acaataaacc gattcacagg ggtaaatata aaaattgaca tgaacaacac
    44521 taataacata agtaaagatg cagatgtgga tggtatagtt aatgtactaa cagaaaaact
    44581 gaatgatgct atggttgtat ctgctgaggg aatagtttag agaggaggtg taatcgtggc
    44641 ttatgatttt tatttagatg gagtacaatt accaatacct ccaccaaagt tagagattaa
    44701 agttacaaat aaaaataaga cagttgattt gataaatact ggagaagtaa acatattaaa
    44761 aaaagaaggg ctatctgaaa taagttttga agcagagttt acacataata aattaccttt
    44821 ttatcgtgga acttttaggg atgttcaatt ctttttaagt aagctagaat tactaaaaac
    44881 tgattgtaag ccatttcaat ttattgtatc gagggaaatg ggtggaaaag tactatttaa
    44941 cactaatatg aaagtgtcat tagaagaata taacatagta gaagatgcag acaatggttc
    45001 agatgttaaa gttgcaataa agttaaagca atatagagat tactcaacta aaaaattagt
    45061 tcctgcaact cctgaaaaga caaactatgg taggactccc actccagtca tgaaaccaaa
    45121 agaatttaga ccagattcat ccaataagcc aaatggtaaa acatatacag taaaagcagg
    45181 ggatagcctt tggtcaatct gccagaagca acttggtaat ggttcattat ataagaaagt
    45241 atatgagtta aataaaacaa tgatggataa agctaacaag ggtaaaaaag tacctaaata
    45301 cacaatttac aaagggcagg tgttaaaact tggctgatga attagttctg gcaaatgata
    45361 gggatgtaag gctagttatt gcacattggg aagatttcta cgaaccagtt gtccttgatg
    45421 gtatcacatg ggagatagaa agaagaggaa caccttctaa gttagaattt acaatagtta
    45481 tggatgatat attagagttt tgcgaaggaa attctgtaag gctgtattat aaaggaatag
    45541 gtatcttcta tggatatata tttcagaaga aaagagataa agaaaatcac attaaaattg
    45601 ttgcttacga ccagctaaga tattttaaga ataaagatac ttatgtatat agtaataaaa
    45661 ctgcaagtga acttgtaaaa atgttggcta aagattttaa tttaaaatac aatgtcatag
    45721 aagatactaa gtataaaata tctaggatag aagaaaataa aacactcttt gacatgatac
    45781 taacagcact agatgatact ctaagagaga aaaaggaaat gtatgtttta tatgatgagt
    45841 ttggaagaat aacattaaag aatgttgcat caatgaaact tgatacggtt atgaacaatg
    45901 atgtaattga ggattttgac tataattcat caatagatag tgatacttac acaaagatta
    45961 aacttgtcag agacaacgag gagtcaggaa aaagagatgt gtatattgca caagattcta
    46021 cacatatgag aagttgggga atactacaac tatttgatac agtagataaa aacatgagtg
    46081 aagcagagat aaagcaaaaa tgtgatatac ttctaaaact atataataag aaaactaagt
    46141 cattaagttt aaaaaatgtg ttaggagata ttagagtaag agcaggttgt ttagtacctg
    46201 tttttttaga tttaggagat attgatttac aaaattatat gttagttgag aaagtaaagc
    46261 acacatttga aaataattcg cactttatgg atttgactct tgttgatgga gatgaatttg
    46321 cttcttattc ttcaagctca tatagtagtg gaaatactaa taataaagat gaaaagaaaa
    46381 atggtcctgc acaaagtact acaagtaaag aagacaatga tatgataaat aaattaaata
    46441 aagtatttaa aaataagtta tcaaatacag gaagtatatt tgttaaatat tctaatgctt
    46501 acaaagtcaa tgcagcttta atggctgcta tttctataca tgaaactggt aatggaagtt
    46561 cttcactttg taaaaataaa aataatttct ttggaatgaa aggaatgtct tttggctctg
    46621 tggatgaagg aataaaaaga ggtataagta atttatcaag aaactatatc catatgggaa
    46681 gaaaaacatt agaaagtatt agagacaaat atgctccact ttatgatagt cctcttaata
    46741 aacattgggt accaggagta aataagtttt ataaacaaat aacgggaaat gcatatagtt
    46801 ctaatagtgc aggtacaggt gttagaagca acgaggaagc agaaaagaat ttaaaagata
    46861 taacttatca agttcaaaat agcaacaatg ctaatacatc aacaaacaat aatagtaaag
    46921 taaataaagt tattcaagaa gcaaaaaatc aacttggcaa gccttacaaa tggggtggta
    46981 atggtccaaa gagttttgac tgtagtggtc ttatggtgtg ggcattcaaa agaggtgcag
    47041 gtataaatct caaaagagtt tcagcagacc aatcaaatga tagtagagga aaactattat
    47101 gcaacataaa tgatgtaaaa gctggcgatt tagtattctt tgcatacaac caaggaaaag
    47161 gaaatgtaca tcacgttgga ctatgtatag gaaatgacaa gttcatacat tcaccaaata
    47221 ctggtgatgt agttaaaata agcagtttaa gtggtagaca aaaacaaaaa catgattttg
    47281 caagagctag aagattcttt taagtgaggt gataatatga gccaagattt attacaaata
    47341 ataaagaaag ctgcaatgga tgcagtagaa acaagcaacc caatgagggt tgtatttgga
    47401 acaatagaaa gtattaatcc tctaagagtt aagatagaac aaaaactatc tattggtgaa
    47461 atttttctaa tacaaacaga tacatttaaa agatatacag ataaaaaaat aggagataaa
    47521 gtagtcttaa ttcgtatgca aggaggacaa caatatttag tattggatag gatgtgatga
    47581 agtgttacca agcgataatt tagattatga cattgaagat gtatcaataa ttaattttga
    47641 tgtaaggcaa gaaccaagta agacctttaa attaaatata gaaaaatcta agatagatgg
    47701 tatttgtgat gatgttgaag cattaaaaca aaccatcttt ttaattttaa acacagagag
    47761 ataccaacat ctaatatata gttggaatta tggagtcgag ttgaacgacc ttattggaga
    47821 gcctatatcc tttgtaatcc ccgaacttga aagacgaatc aaagaagcac taattcaaga
    47881 tgatagggtt gaaaatgtag ataattttga gtttcaaaat gtaaagggta aagtacattg
    47941 taagttcaca gtttacagta aatatggaaa tataaaagca gagaaggtgg tgagtgtata
    48001 attgtttgag ttaatgacat ttgaaaatat aattaaaaga atgttagata gtgtaccaga
    48061 tacttttgat aaaagggaag gttctataat atataatgct cttgctcctg ttgctataga
    48121 acttacagaa acatacattg ccatggatga attactagac caaacttttg tagatactgc
    48181 tagttattac tatttagaga agagatgtaa agaaagaggt attacacctt tacctgcaac
    48241 caatacaatt gcaaaaggag tttttaatat agatattcct attgattcaa gattcaactt
    48301 aggagaatac aattatgtgg caattgagag aatatctgaa aaaacatata aaatgaaatg
    48361 tgaaactact ggacctgtat ttgaacttgg tcagttgatt ccaattgaat atgtagacaa
    48421 attagaaact gctgagttaa ctgaaatact aattaatgga gaagatgaag aaagtgaaga
    48481 tagtttaaga caaagatatt atgatagcct aaactcacag agttttggtg gaaatatgca
    48541 aaattataaa gatgaagtta acaaaataca agatgttgga ggagttaagg tttatcctgt
    48601 gtgggacggt ggaggtactg ttaagttagt aataattaat tctaacttca aagttccatc
    48661 tagtgattta gttaatttag ttcaagaaga aattgatcct ctacaaaacc aaggagaagg
    48721 tcttggatta gcaccaattg gacaccgagt cacagttgaa ggagttacaa gtacaactat
    48781 aaatatatca gcagagataa catacaaaaa tggctacact tgggagaata taaaatcaat
    48841 tgcagaagaa gcaatagacg actatttaaa tgaacttaat atgagttggg aagatgaaga
    48901 aaacttaata gttcgtatat ctcaaattga aactagatta cttagtattg atggagtatt
    48961 agacattgca aatacaatga taaatagcat tgcatctaat cttaatgttg ataaagattc
    49021 tatagtatta agaggtgaag tagttggata aagagattaa tctaataaat tacttaccgc
    49081 aaatcctacg agataaagaa gaatatataa aagtatttaa tgtagaaaac aaagaaataa
    49141 aaacactaca tgaaaaatta aatgacctat caaatgacca gtttttagag gatttaactc
    49201 caagtggcat aaaaagatgg gaaaagataa tgtctataac tcctaaaagt aatgagagtt
    49261 tagaagatag aaggtttagg atttttagta aatatataag taaattacct tactcagaga
    49321 gatttttaag gaactggcta gataatgtag ttggagaagg caattatgag ttaactataa
    49381 ataatgctac ttataatata catcttgaaa gtgatgctag aaatcaagat tggtttgagg
    49441 aagttcattc ttttgtaagt aatattaagc catgtaatat gactttagat tacactagag
    49501 tgcttataag caaagacaat tatatgaatt ttggtataac aaccctaatg ggtcaagaaa
    49561 taactatata cccttggagt ccaccagata tagaaactta tggagaaatt gatgtattaa
    49621 ctggcaatgg agttggatac caagagataa caatatttta ggaggtgata tattggctat
    49681 agataaaagt tattacacta taattacaga tgtaggaaaa gcaaagatag caaatgcaag
    49741 tgtcacaggt aataaagtgg gatttgtaaa aattcaactt ggtgatggag gagggagtga
    49801 atatactcca actgagagtc agacagctct caaaaacgtg gtatgggaag gcaatattgg
    49861 aaatacaact acagatgaaa ctgcaccaaa ttgtataata ttagagagtt taataccatc
    49921 aagtgtaggc ggatttatga taagagaaat aggatattta gatgatgaaa ataatttaat
    49981 tgccatttct aaatacaaag agtgttataa accttctata gaacaaggtg cagtggtaga
    50041 catgaaggtt aaaactgtgc ttattgtatc taatgtaaat aatatagaac ttaaaattga
    50101 cccaacaata atctttgcaa cactcaaaga tatacaagac ttagaaacta aaataggtac
    50161 tgttaatact aaaattgata caactaaaac agagttaaat actagaattg acacagaaaa
    50221 tgagaaacaa aatattaaaa ttgaccaatt aatcgcaggt ggttcaaatg tatctcatac
    50281 gcatattata gagattgatg attggatttt aaataatgaa actaatatgt atgaagtaac
    50341 tataaatcat ccactattga ctaaaagaat actaatagct ttatatgatg aaattggtga
    50401 agcacttaca ccaaacgcta gggctattga tgataatagt attcttgtta gaaatgaaga
    50461 aaatattaaa atgtatgtat atttgataaa tggaaatgca gaaactcatt ttataaatgc
    50521 aactgtggat gataacagag tgtctgaaat gactacttat tcatctaaga aaatcgaaga
    50581 tagatttctt aatttagaag aaaaagtaaa tggtggttta tctagtattg caacaagtgt
    50641 aaatgagttg ataacttatt gttagagagg agagtgagaa aatgcagaca gaatggaact
    50701 ttgggta
//
LOCUS       DAYAKB010000023        49651 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.023, whole genome shotgun sequence.
ACCESSION   DAYAKB010000023 DAYAKB010000000
VERSION     DAYAKB010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.023"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(305..499)
                     /locus_tag="ACGI3L_001607"
     CDS             complement(305..499)
                     /locus_tag="ACGI3L_001607"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF012678.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFG9197320.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFD"
     gene            769..1410
                     /locus_tag="ACGI3L_001608"
     CDS             769..1410
                     /locus_tag="ACGI3L_001608"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase family protein"
                     /protein_id="HFG9197321.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            1436..2980
                     /locus_tag="ACGI3L_001609"
     CDS             1436..2980
                     /locus_tag="ACGI3L_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9197322.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(3180..3806)
                     /locus_tag="ACGI3L_001610"
     CDS             complement(3180..3806)
                     /locus_tag="ACGI3L_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9197323.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(3941..4657)
                     /locus_tag="ACGI3L_001611"
     CDS             complement(3941..4657)
                     /locus_tag="ACGI3L_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFG9197324.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            5083..6297
                     /locus_tag="ACGI3L_001612"
     CDS             5083..6297
                     /locus_tag="ACGI3L_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFG9197325.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            6915..8243
                     /locus_tag="ACGI3L_001613"
     CDS             6915..8243
                     /locus_tag="ACGI3L_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197326.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(8371..9561)
                     /locus_tag="ACGI3L_001614"
     CDS             complement(8371..9561)
                     /locus_tag="ACGI3L_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9197327.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIREETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEVLLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9667..11046)
                     /locus_tag="ACGI3L_001615"
     CDS             complement(9667..11046)
                     /locus_tag="ACGI3L_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9197328.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(11077..12285)
                     /locus_tag="ACGI3L_001616"
     CDS             complement(11077..12285)
                     /locus_tag="ACGI3L_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197329.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(13310..14764)
                     /locus_tag="ACGI3L_001617"
     CDS             complement(13310..14764)
                     /locus_tag="ACGI3L_001617"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9197330.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYEMPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLGKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(14784..16655)
                     /locus_tag="ACGI3L_001618"
     CDS             complement(14784..16655)
                     /locus_tag="ACGI3L_001618"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9197331.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQSTTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(16645..17505)
                     /locus_tag="ACGI3L_001619"
     CDS             complement(16645..17505)
                     /locus_tag="ACGI3L_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9197332.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKTLNIKASDYLSLTLLDHLEF
                     LLKRCKKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSE
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            complement(18253..18657)
                     /locus_tag="ACGI3L_001620"
     CDS             complement(18253..18657)
                     /locus_tag="ACGI3L_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HFG9197333.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(18849..20036)
                     /locus_tag="ACGI3L_001621"
     CDS             complement(18849..20036)
                     /locus_tag="ACGI3L_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide family glycosyltransferase"
                     /protein_id="HFG9197334.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(20068..20283)
                     /locus_tag="ACGI3L_001622"
     CDS             complement(20068..20283)
                     /locus_tag="ACGI3L_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006774905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HFG9197335.1"
                     /translation="MVPPKGKFFFGAVVVGERGQIVIPKEAREVFNINAGDKLLVLGD
                     EERGLGIVHQRDLINFIGHVGVVHKEE"
     gene            complement(20311..20502)
                     /locus_tag="ACGI3L_001623"
                     /pseudo
     CDS             complement(20311..20502)
                     /locus_tag="ACGI3L_001623"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(20621..20749)
                     /locus_tag="ACGI3L_001624"
     CDS             complement(20621..20749)
                     /locus_tag="ACGI3L_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197336.1"
                     /translation="MKDYKYKGYFEGVEIFDNVNDLNLNTLTTVSRFVFVFLFTIT"
     gene            20971..21720
                     /locus_tag="ACGI3L_001625"
     CDS             20971..21720
                     /locus_tag="ACGI3L_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HFG9197337.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELIST
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFEIITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(21896..22261)
                     /locus_tag="ACGI3L_001626"
     CDS             complement(21896..22261)
                     /locus_tag="ACGI3L_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFG9197338.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWRSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(22277..23053)
                     /locus_tag="ACGI3L_001627"
     CDS             complement(22277..23053)
                     /locus_tag="ACGI3L_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9197339.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(23464..24891)
                     /locus_tag="ACGI3L_001628"
     CDS             complement(23464..24891)
                     /locus_tag="ACGI3L_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFG9197340.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFVVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(24952..26880)
                     /locus_tag="ACGI3L_001629"
     CDS             complement(24952..26880)
                     /locus_tag="ACGI3L_001629"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9197341.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(27025..27867)
                     /gene="licT"
                     /locus_tag="ACGI3L_001630"
     CDS             complement(27025..27867)
                     /gene="licT"
                     /locus_tag="ACGI3L_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFG9197342.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNKSIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(28214..29584)
                     /locus_tag="ACGI3L_001631"
     CDS             complement(28214..29584)
                     /locus_tag="ACGI3L_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9197343.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIENFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            complement(29623..30294)
                     /gene="pgmB"
                     /locus_tag="ACGI3L_001632"
     CDS             complement(29623..30294)
                     /gene="pgmB"
                     /locus_tag="ACGI3L_001632"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFG9197344.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     INREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGVKDEFDCIVNPSLLKRGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            complement(30296..32686)
                     /locus_tag="ACGI3L_001633"
     CDS             complement(30296..32686)
                     /locus_tag="ACGI3L_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFG9197345.1"
                     /translation="MSLIFTTKDQLVELGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGVRTYFEATNDEEFMMQNGLEILIETSRFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVFVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(32712..34160)
                     /locus_tag="ACGI3L_001634"
     CDS             complement(32712..34160)
                     /locus_tag="ACGI3L_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HFG9197346.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKN
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MSYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(34565..35452)
                     /locus_tag="ACGI3L_001635"
     CDS             complement(34565..35452)
                     /locus_tag="ACGI3L_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9197347.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(35552..36001)
                     /locus_tag="ACGI3L_001636"
     CDS             complement(35552..36001)
                     /locus_tag="ACGI3L_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9197348.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(35991..37898)
                     /locus_tag="ACGI3L_001637"
     CDS             complement(35991..37898)
                     /locus_tag="ACGI3L_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9197349.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(38166..40061)
                     /locus_tag="ACGI3L_001638"
     CDS             complement(38166..40061)
                     /locus_tag="ACGI3L_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFG9197350.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(40097..40975)
                     /locus_tag="ACGI3L_001639"
     CDS             complement(40097..40975)
                     /locus_tag="ACGI3L_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFG9197351.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(41518..41688)
                     /locus_tag="ACGI3L_001640"
     CDS             complement(41518..41688)
                     /locus_tag="ACGI3L_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197352.1"
                     /translation="MSALLYGVCNKSISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(42085..42297)
                     /locus_tag="ACGI3L_001641"
     CDS             complement(42085..42297)
                     /locus_tag="ACGI3L_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197353.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(42298..42714)
                     /locus_tag="ACGI3L_001642"
     CDS             complement(42298..42714)
                     /locus_tag="ACGI3L_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197354.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(42782..43195)
                     /locus_tag="ACGI3L_001643"
     CDS             complement(42782..43195)
                     /locus_tag="ACGI3L_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197355.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(44028..44657)
                     /locus_tag="ACGI3L_001644"
     CDS             complement(44028..44657)
                     /locus_tag="ACGI3L_001644"
                     /EC_number="3.2.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
                     /protein_id="HFG9197356.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALRQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(44736..45698)
                     /locus_tag="ACGI3L_001645"
     CDS             complement(44736..45698)
                     /locus_tag="ACGI3L_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197357.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKVKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVIEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(46460..>49651)
                     /gene="cbpA"
                     /locus_tag="ACGI3L_001646"
     CDS             complement(46460..>49651)
                     /gene="cbpA"
                     /locus_tag="ACGI3L_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HFG9197358.1"
                     /translation="EGDTNAGDAEGDTNAGDAEGDANAVVVEEEATAEEPTSVGDFKI
                     SGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIKT
                     ASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVVNRD
                     IEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGNT
                     ESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGIITAKGAYHGAG
                     IGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGTN
                     RGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDLE
                     KKTKVFMNKISLTYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQGILYLWFSDQ
                     FKGSEVSVNLVVIDKITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDTPPYLIIKRY
                     DGLPFEEDVEKSFLDWIFKDGGIPIITPKGEKLTDKKFMTISSQRLNEETMEPDINLG
                     SDDLTKQVDAGKYQLSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTETSLVVEESK
                     AKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGSE
                     SHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDVD
                     GDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWKPDK
                     NIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDNG
                     GNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPD
                     NGGNSKPDPDNGGNSKPDPDNGGNSKPDIDTDGDGKPNINIDTDGDGKPDINIDTDGD
                     GKPDINIDTDGDGKPDINIDIDGDGKPDINIDTDGNGKPDINIDTDESLDSNVGQNVQ
                     TGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
BASE COUNT        16459 a         8545 c         5413 g        19234 t
ORIGIN      
        1 gtgtacttcc ctcaagagga atagtcgttg aagtttctcc tattcggagc ttacctgctg
       61 attgcccatt ttaaagtact taggatttaa ccttatacca tctaaccaat tttttctact
      121 ttcgtaactt tcacacttag gtttatttca tccttatgtt ttagtttggt tagctttagg
      181 ggtttccagc aattcaagta gtattggata ggttctatcc tatctctaca tataggtttc
      241 cctatatgct gactatttta gctattaact catgactaaa gtcacgagtg tgcgtagcta
      301 ttttttaatc aaagtgtaca acttctatac ctttttctat taaattcaat gtaactcttt
      361 tatataactt gtctaatggc tctacatttg gagtagtaac taacaaacat ttctttccat
      421 attttcctat tattctaggt aattcactta aagttccttg tccaaaattt attcttgatg
      481 gttgataaaa gttaatcata tttttcctcc cttaaattat tgccttcata ttcaaattat
      541 acatatcata ggatttttaa ggcaatacct tcactgttaa ctcttattta ctaaagctta
      601 tggtaattat tagacaatca atgttttatt attaccatat cattatgtaa attttattaa
      661 gtacccatgt tataatttta taatcaatct tattgtataa ttgacttaat aataaaaata
      721 gagtatatac acttttttat gacaaatagc ttaaaggaga attaaattat gaaatatttg
      781 atagacagtg ctaatcttga tgaaattcaa aagtgtctaa agtatggatt taagggaata
      841 accgctaatc catctatgta tcttaaagag aaagtaaact tccatgaatt tattgagaca
      901 tgtgctaatt taaatccaga aatattaact gctgaagtca ttggaaataa tttatacgaa
      961 ttaattaatt catgtgataa gatattaaat ataaataaaa acactataat aaaaataaat
     1021 ttctctgaag ttggcttaga acttataaac atattaaata gtaaaggtgt aaaaactgca
     1081 tgtaccttga ttttcaatgt aaatcaagca tcattagcta taaatgcagg tgctgattac
     1141 ctattccctt ttataggtag aaatgatgaa aatgggaatg atggtataaa aaaccttaca
     1201 gaaatatgta accttatatc aataaatgga tataatacta aagttgttgc agcttctatt
     1261 aaaaatgtat tccacttaac tcaagcatct ctttgtggat gtgattatgc agctgtaaca
     1321 tatgatttat ttaaaaaagc ttcttttaac cagcttacaa tagatggtgc caatactttt
     1381 gaaagagatt ggtccaaggt taataaatag taactaagat ttaggagggt ttgcattgaa
     1441 caaaagatta ttagatattg ctgaattatt actcaacagc tcagactata ttactgtaga
     1501 tactattgcc gaagaattaa aagttagtaa taaaactatt cgtaatgacc ttgttatttt
     1561 agatgaatgg cttttagagt ttaatttatc cctagataaa aaaactggtt caggggttat
     1621 tattctaggt aatgaagata taaaacttaa agttattaga gatatcaatg ataaatcaaa
     1681 ttgtatatat gcatactctc ctgaagatag aaaaaggtat attctaagta aattatttat
     1741 taaaaattct aagtttagga ttcgtgatat ttgcaatgaa ctacatgtta gtagagctac
     1801 tgtgcataaa gacttggtag ttattcaaaa ttttttgcaa aactttaaag tgactctagt
     1861 tagaaaaacc aataatggag tatatttaga gggaaaagag aaagatattc gaaaagcaat
     1921 ttttgaactt gctacggtta ataaaagtta tactgaactt aaagaaatat tattctcgaa
     1981 atctaatgaa tgcaaagata ccccatcaac aaaaatattt aaggagctat ttaactatga
     2041 ttttgagaaa ttatctcaaa tcactctaca caccttacaa gtagaaaaaa gtaaccttag
     2101 tgatgagtat tatataaact tcttaataca tatagctata tgtattaaaa gaatttcaat
     2161 taaaagatat attaacttat ctgaaggttt ttttagagaa ttattagaac atgaatactt
     2221 tgaaaaatca aaaattttat gtgctaacct aagtgaagct tttgacgtag aatttattga
     2281 tgaagaggtc tgttatatcc ttcttcatat agaaggatta cttaaatcaa taaagaaaac
     2341 tactactctt gaacctctta aaaatgaaga aattacagag tataatctat ctgaagcaat
     2401 agctgttcat tggggaagta tactaaattt aaacttaaag gatgatttaa tattaataaa
     2461 gtctcttgct aatcacctta aatcagttct acacagaata aactatgggt ttactattac
     2521 aaatcccata ttaaatgata taaagagaac atttccttac acttataagg ctgctaaaga
     2581 gtctaatact gttatcaaac agttgatgaa ttatgaagtc aatgatgacg aaataggata
     2641 tcttgcttta tatttaatat cagcaataga tagaagcaaa tctcccctaa atactatttt
     2701 aatatgtcac tgtagtgatg gtgtatctaa tttattagtc caaaagttaa gttttgaatt
     2761 taatcagatt aatatagtta aatctatacc tctatcttct atttcattta cgaactttga
     2821 tgatgtggac ttaatactaa ccactgctcc tgtagacttt gaacataatg ctgaactgat
     2881 aaatataaat gctcttttaa gtaagaatga tatttctaga cttagtacaa ttataaaaaa
     2941 actatattct gaaaaaaata aaatattatc ttataaataa acaaaaatag gcttgtctca
     3001 acatagagat aaacctattt ttcattgtcc aaatgataaa aatatatttg atttcataga
     3061 aaaagtgcct catgaactaa aaaattcatt ttgagacacc ttcatttttt atatttaatc
     3121 tttttattta agcttttata ttttttaaac ttttatattt aaagtaaatt ttattatttt
     3181 tattgagcac aagcattatt tatattatta atttcttcag tattcttacc aaactttgta
     3241 gttacaaatc ctattgtttt tattatgagt aataaagata tcaatgaata tatagatatc
     3301 ataaaattct tacttattat tccagacgct actattataa atccatctag cataaataat
     3361 ataactggca acttcagaaa cttaattacc ttattaataa gcattgcaac taaatcagtt
     3421 ccaccagtac tacagcccct tattattgct atccctatag cagttcctac caataaccca
     3481 cctatcactc ctgctactaa tagattgtca gttatgtgag tttgtggtat tacttttaag
     3541 aataatgggc ccataagagt tatatataat gtttttattc caaaaccttt ccctaaaaat
     3601 aataatccca ttactaaaag tggcatagat attcctaatg atatattctc aacaggcatt
     3661 gataagaatg tgctaagtac gactgataat cctgttatcc ctcctggagc taatgtatgt
     3721 tctgcaaaga aaaaattaac tgctaatgcc attaaaaatg ctgatattgt tatcagtaaa
     3781 taatctttta tcatttcttt tttcatttaa taacctccta tgattatatt gtttcagtat
     3841 aaaaaatcaa ttaaattagt ctagcttcct gtagtttttc ataaaattaa tgcttcctta
     3901 aaacattaag aaagcatctc ttttatcata gtttattatc ttattctaaa ccaaactttg
     3961 tagctgcttc atctatagct tttctacaat tcttaacacc tgctgttata ccatctttat
     4021 ccttgaatat tgctgaagat aatattacaa cgtctggatt acattctatt aatggctcca
     4081 tattgtctgc tcttagtcca ccatctattg ctaattcaca cttaggattc ttttcgtcta
     4141 tcatttttct agctcttttt actaaatcaa cagcactctt tctccatccc cagttatctt
     4201 ttccatcagt ttcatcaaca ccatgaacga ctatttgcaa tctatctata tcatatatag
     4261 cttcatcaac aaaacatagt ggtgtgtaac atccaattgt taatcctact ttcataccaa
     4321 attctctaca gtaatttatt atgtatgcaa gaggagcacc taaaaaatgt tctgctggta
     4381 ttatcaacaa gttacatcct gctgctgcta ttttttctat aaataatcta tcacaatctc
     4441 ttgtgtatat atggcattct attggtttat ctgtcaccgg tcttattgct tctattattt
     4501 gatgaccacc cataagttgc atatttttta agtcatgcat atctgctgca tctgaatgta
     4561 cgtagtctac acctgcatcc attgcttctt taactacggc tgatatatga ccgtaattta
     4621 catgtgctaa tcctgctgct atttttatgt gtttcatatt tgtatacctc catattttac
     4681 tttaattagt attaaatatt agtttttaat atttttttaa tattttttaa tccagtatta
     4741 cttttattta gcattacttt tattgctgta tatatttctt ttatgaactt attctgcttt
     4801 tgttaactgt gaacttattt tgctttgtaa attaatatta cactgatata ttttttttca
     4861 caacactttg actactcctt aaaagtacct ttatattgtg gtaaattata gacattaatt
     4921 gtatataaaa agttagtttt ttaccacatt cttatggcat ttattgtcta tactaactca
     4981 attgatatag ctagttcatt taatatataa tcagactata aatataaatt tactcgataa
     5041 aaagtaccat tcataacaat attaatgaaa gggagatgta aaatgagaaa ctgtattatt
     5101 gcccaatctg gaggccctac agctgttatc aatgcttctg cagttggtat ttatgaaaaa
     5161 aatttagaaa ctaaatactt tgataaagta tattttggta tcaatgggat tgaaggtata
     5221 ttaaacaaaa atataataga ttcagactcc ttaaacaaag ataatgtatt aaatttaaag
     5281 caaacacctt cgtctggtct tggttcttgt agatacaaac tggctgatta taaaataaat
     5341 tcttatgatt atgatagagt tataaatata ctagatgaat ataaaataga tacattattt
     5401 tatataggcg gaaatgattc tatggacaca gtgatgaaat tttctcaata ctgcaaaaac
     5461 actacttgta aaataaaatt tataggtatt cctaaaacaa tagataatga tttattagga
     5521 actgacaact gtcctggatt tggttctgct gcaaagctta tttctacact aataatggaa
     5581 acatacttag atttttctat atacaaaaat aatggtatat ttatagtaga aactatgggt
     5641 agagatactg gatggttagc agcttcttct tcactagcta gacttaatga tactccactt
     5701 gttgatttaa tataccttcc agaaattgat ttctatgaag ataagtttat agaagatgtt
     5761 agaaaaatat ttaaagaaaa aaataaggct tatatagttg catcagaagg tataagggat
     5821 aaatacggca actttatatg cgaacaaaaa acttctgctc atgataaatt tggtcattcc
     5881 caattaggtg gagtaagcaa ctatctaaag aatcttatag tatcatcatc aattacaaca
     5941 agagtaaaaa ccttagaact tggtgtaata caaagatgtg ctatgcattt agcttcagat
     6001 actgatttaa aacaagcagc tgaagttggt gcatatggga tagaactatc taaaaaagga
     6061 tatacaggag ttatggctat cattaataga acatgcaata atccttataa gtatgaagtt
     6121 agtcatactg atatttctaa aatagctaac aagacaaaat attttcctaa agagtggata
     6181 aatgaagaat gtaattatat aactgatgaa gccctaaatt atctatatcc acttattcaa
     6241 ggtaaaccag atatcaaata taaaaatgga ctaccttatt tttcaattat ttactaggaa
     6301 attattataa tttgatatac actcaattct atcgctctta aatacctaag tggctgttaa
     6361 ataaaattat aaattgttat atgacagtca cttaatcgtt taattattta actgtttagt
     6421 tttttaattt tttaatcttt ttaatactaa tacaatttgt tgtaataata tctcacaccc
     6481 attttcattt tggatagatt ataattagtt agacaataaa tattttgtca tgatattatt
     6541 atatatagtg atacaaatag aaatactttt atcatggcta gaaaaacaaa gattacacaa
     6601 aggatttaaa agtcaaacaa cttcaattaa aataaatggt taaaataact tctaaatcaa
     6661 ctacataaac aataaaagaa cataaagtag ttaaatctac aattataaaa ttagtaagac
     6721 tataataact taaataaaat taaagttaac aaagactatt aaagttagca aatattcctc
     6781 tacctaaata attgcttttt ataaagagtt atttatttta attgaattta attgaaatac
     6841 gattttaact agaacaatag attaatgtaa tatttaatat aaaataatta taataattga
     6901 aaaggaagta atctatgatg aaaatagcag tcataacaac cgaattttta aaagagtttg
     6961 tagataattc tataaaaaag ttaaatatta atgcagaaat tgaaatatat atctatagag
     7021 atttttctca tgttggagat ttatatttag aaatagaaga taggtttgat ggatttgcag
     7081 ttagtggccc catccccaaa aaagctatta caaaaaaggc tggaactatt aaaaaacctc
     7141 tagttgattt tggtactgac ttacaaagtt actatgatat gtttctaaag cttatcttta
     7201 aatataatac attagatttt tccagagcat actttgactt aacagactgg gcagataatc
     7261 caaaagatat atcatattat ttatcaaatg gcacatttgg agacttaatg gatagtattg
     7321 atgaaaatgc atctaaaatg agtttatctg acatagcaaa acttgaaaaa aagattgcaa
     7381 aaaaacatat taatctatgg aatgaaggga aaatcgattt ttctactact cgttttagta
     7441 gtattgttcc tatgttacaa aatgcaggag taaactttca tttcatatac cctgatatag
     7501 atttattaaa aaatactttt aataacttaa taaaagatat tcatttacat agaatgaagg
     7561 gaaatcaacc aagtgtaata tatataacag ttaaagatac aaattatgat gactctactc
     7621 tagaccaagt ttataaaata ttaaatagta ttaaaaaaga taaattaacc gattttataa
     7681 ttgaaaaaaa tagtaattct tttaaaattt tcactaaatg tgaaacgatt aaatcattaa
     7741 ctaaaaattt tactgcatgt tatataaaag aatctattga aaatagtaca aatattaaag
     7801 tatgtattgg atatggaatt ggtaatgata taaagcaagc tatgtctagt gccataagtg
     7861 ctaataagga atctaaaata aatcctttaa attacagttt cttagttaac gaaaattatg
     7921 agacaatagg acctttactg tgtgataagt tacttactgt ttcaaataaa gtaactccac
     7981 atataaatac aattgccaaa agttctaaat tgtctactct tactattcaa aagattatat
     8041 ctgttactga aattctacaa agagatgaag ttactcctaa ggaattatct tcatgtttaa
     8101 atgtaacagt tagaactgct aatagatttc taagtagtct cttaaagtct ggaaacgcta
     8161 ctatattata tgaaaaacaa aactcaacaa aaggcagacc tgaaagggta tacaaattat
     8221 ttatatcaga aaataaatat taaaatccaa aatgcataaa aatattttat catctaatat
     8281 taagtaaaat tatatatgac tttctaaaag gtatatcttt gcatcttttt aagatatacc
     8341 ttttatgata tttaataata ttttatgtta ttatctacta aaattatttt ctaaccattt
     8401 tactgcacaa tgagcaaata aagctgaacc ataaactaat ccctcttcat taaaaattgc
     8461 tttaggatta tgcataccaa aattatatcc ctgactaata cttcccattc caatccataa
     8521 aaatactcct ggaaccctta gtaaaacctc tgaaaaatct tctgaaccca ttgcagatgg
     8581 aaagtctatt acattttcat ttcctataac ttctttaaca taagatacaa tctcatctcc
     8641 tacatccaaa tcatttataa ctgcaggagt ccccatttta aactccactt tagcatttcc
     8701 tccaaatgat ttagctattc ctgtagatat ttcaataatt ctatttttta atttttctct
     8761 aacaaattgg tcaaatgttc ttaaagttcc tgacatagat gctttatttg gtatagcatt
     8821 tggtacgttt cctgcattaa acataccaat agttaaaact acaggctctt tctgaggttt
     8881 ttctcttgaa agtatagtgt ttaatgctat ttgtatatgc gacattatgt ttattgggtc
     8941 cactccaaat tcagggcttg ctccatgagt tgcttttcct tctactgtta tttcaaatat
     9001 atccgcagat gccatagctg gaccacgtga ataagctact tgacctgtgt taagaaattt
     9061 acccaccata ctgtgaaatg ccatagctgc atcgacctga ggattttcta atataccatc
     9121 atcaatcatt gattttgcac ctctggtagt ctcttcatct ggttcaaata caaactttac
     9181 tctaccttta agtaagtgct tattatccat aagtatttta gctgctccta agagcattgc
     9241 tgtgtgatta tcgtgtccac aactatgaga tgcatcttta ttcttacttt taaaaggtaa
     9301 atccgtctcc tccctaatag gaagtgcatc catatctgcc cttaataata aggtctttcc
     9361 accattttca ctgtctaaaa cagctactat tccattatta gacgtcaatt tcggagaata
     9421 tcccattttt tctaaagtac tggtaacaaa ggttactgtt ttcggtagat tgcaaccaat
     9481 ttcgggattt tcatgtaaat accttctcca tctaataatt tccccttcta ttgactgcgc
     9541 ttctttaaaa aaatttttca tattccttcc tcctaatcag atagtcagca aaatctcact
     9601 ttcttttagt aatgaaatga tgctgatata aaaattataa ttttatatat taaatttcat
     9661 gtctttttaa ggagttggaa tatcatctgg aataggacat ttatatgttt taccattcat
     9721 agatttatca aattcttctt ttgccttttt agctatctct ggattattta atattttagc
     9781 tccaaacata gccataatct ttgatgcata tatcatacct ttttctccta tagaacttcc
     9841 tgcacaagat gtaaactgcc agctatgacc tggtgctcct agattcgtac accctgtaaa
     9901 aaagtatgct gtcggaacta tatgcattac atctccaata tcagtagagc cataactatt
     9961 aaagtttgta acatttcctc caccataata tagatgagtt ccttctggca aattatattt
    10021 acttatcata gccttatatt gttgtgggct ttgtctatct aattcagctg caaaatccaa
    10081 ttcctctcga gtccaaggct cttgtttaat ctcattcata cattctgata caagatttgc
    10141 taaaacatga ttgtttaaag tattataaca ccctcctaaa aactctactt caacttcagt
    10201 ttcagtcatc attgcagctc cttttgctac ctttacaagt ctttcatatg tactttctac
    10261 agcttctcta cttaaagctc ttgtataata ccatactgat gctttatcag gaactatgtt
    10321 gggtgctact cctccatctg taattgtata atgaatcctt acatcagaag taacatgttc
    10381 tctcaaataa ttagctccca cattagtaag ttccacagca tctagtgcac ttcttccatt
    10441 ttgagggtct gaccctgcat gtgcagtctt tcccttaaag tgaaacttta cagagttaac
    10501 agctgttgaa gtaccaattg tagcttcact aattttattt ggatgaaaat ttatagctaa
    10561 gtctaaccct tcaaacgctc cacctctagc cataaatcct ttacctgtta attgttcttc
    10621 tcctggacat gcataaaata ctatagtccc acttaagtta ttttctatca tctctctttt
    10681 aagccctact actgccccta catgtgctgt acataataaa ttatgcccac atccatgacc
    10741 atatgcaccc aattcaaatg cttcttgctt tgttgaaact ttttgattta aaccaggtaa
    10801 tgcatcaaat tctcccataa aacctataac tggtttacct gaaccaaaac tagctctaat
    10861 agccgtggct aaacctccta cacctacttc cacatcaaat ccttcacttc ttagaaagtt
    10921 tgctgtattt tcacatgctt taaattcttt aaatgctttt tctggatttt cccatatttt
    10981 cttacttaaa tcatcaagtt tgaatctttt tttatctatc tcatttatag atatacttcc
    11041 tatcatttcc tattcctcct ataagtatat ttactatcaa ccaaatataa ttggacctat
    11101 tatactagca aatgccactg atgcaatggt tacagtaaca aatcctccta taatcatctt
    11161 tggtaataaa taatctgttg ccctttgttt ttcttcttca gttccttcca tagcatcaat
    11221 accttcgttg gaaattatct gtgttgcagg ataagctagc atacaagtta caccaattgc
    11281 agctgacatt cttggagaat atcccaatag ttttcctaca attgcagtaa ataatattat
    11341 aaatacagaa cctacaacaa gtattcctat agttggaaca atcatcccaa acaatgctgt
    11401 tggagttacc ttagcaagtc ctccaggtaa catcaacata caaccaaaca ttataattcc
    11461 attagattga gatttatcta aaattccttt ttctaaaaaa cctattcgtg taaaaatcaa
    11521 ccctactaac aaacatgcta tattaggatt taaataatag tttgcagggg taaatcctgg
    11581 tattaaagta gccaatccta caaaattacc aatcatagca acaaatgaaa gctttgcaag
    11641 atacactaga gtagatgatt ttttacctaa atcttcttta aaaattctca tacttggaag
    11701 tttaaaatta ctttttgact catctttcaa aaaatccccg ttatctcttt taaattttaa
    11761 ttctttattt atacaatatg tagttatcgg aataccaaag aacttttgaa atgataatac
    11821 tagaattaca aatgcagcaa gttcaggtct atttgcagct tctgcaacag ttgttacgat
    11881 aatcccagca acagtagaac ctgctattgg aggtgctgct attaaagcat actctctgcc
    11941 aaataacata ctacccactg ttaaacagcc aactcctatt cctacaatac ctactaatgc
    12001 aattacaacc gttttccatt catgacataa gtcttcaaga tttataagtg ttcctaagtt
    12061 agttattaat aaagctatac caaagttgct cattgcagct aatatccctg atgctcctgt
    12121 aatgtctttt ggtaaaatat ttgtccaaaa tcctagtaaa aatataatac atacaaataa
    12181 caatgttgaa attgcacctt ttgttttctt agataaaaac tcactaaaag cataaatcat
    12241 tacacataca gtaaagcaag taagtggatt ccaaaaattt tccattgttg tttcctccta
    12301 aatataataa ttttttatca ataaaacaat aattataaaa tgtatattat gcagttattc
    12361 ttaactacat atggtatagc ttgatatttt ttgatgatat tatatacgtc ctaaattatt
    12421 cctaaaatat ctaaataaat ataactagag ttaactctct aaatattaac tatagttatc
    12481 aacttactag atttcttttt gatttttact ttctacataa ttttacgagt tagaattgta
    12541 cttcaactac tctctatatt agtatacatg ttggaagact tatatttatt taaatattag
    12601 atatagaata catttttata aacgtcttaa attattctta aaatatctaa aacgaaataa
    12661 taatataccc attaaaccaa tattatcaga atatacttca ctttaagtct tctttatata
    12721 gaaattttat ctattagtgc atcccctcct ttgtaaatta gactatttct aaacgaattt
    12781 agatatctta ttcctaggaa ctattactag aaacaaaaat tatttattat attaaatcaa
    12841 tgataagcca tactttaaaa ttctttctat acaagtataa tttatcatat aatgacatct
    12901 atacctttat ctttatagta gtcctaaatt attcttaaat tgacaataaa aataatttca
    12961 ctatttataa aaatacttgt ttttatattg tcaaactatt cttaatatag attataattt
    13021 taaatctttt ctttgtcaat atattctgac atttttccag aaaatttata aagttatata
    13081 gtgagtaaat catactattt ttatataatg agtaaattat actatgaata tgtctaaata
    13141 tttacttaag tataaacata aaaaatgtgt attctccttt ttatagtaat tttagttgcc
    13201 attactttta agaagaatac acactttact ttaaagaccc tatactctat tttaaatgct
    13261 ttactagaca ctaattaaca ttagttccta acttctattt atcttattcc taccctacta
    13321 ctatatccgt agaaaaatct aaaacttctc cattagattt tattacttct ttgtaccaat
    13381 caaatgattt tttcttatat ctcttaaaac ttcctttgcc ttcatcatct aagtcaacat
    13441 agataaatcc atatctctta ctcatctgac ctgtagttgc actgactaaa tcaattggtc
    13501 cccacatcaa atatccaaaa cattcaacat tatcttcttc aattgcagac ttcatttgag
    13561 atagatgctt acctaaatat tcaattctat aatcatcatt tatagttcca tcttcttcga
    13621 ttttatcata tgcccctaaa ccattttctg taattaagat aggtaattga tactttctgt
    13681 aaatatagtt caaggtaaat cttaaaccta tagggtctat tgcccacccc cacttacttt
    13741 gttccaaata tggattttga atcccaccaa ataaagattt atcacctgat aaattttctt
    13801 ttggagtaga tacacttgaa aaataataat taagtcctat aaaatctaac ttaccttctt
    13861 taaatgcttt tttgtcttca tcagtcactt caatagttat attatttttt tcatattctt
    13921 ttaatttata ttgtggaaac ttcccattgc acattgcatc aatttgataa taatcacggt
    13981 cattatctaa aaatgcattt aacacattac taggattaca attgtatgga taaattggat
    14041 ttagtccaaa tacacatcca actttattgt tgggattgat ttctctagcc aactttgcaa
    14101 cctttacacc cgccaaagtc atattatacc ctacatttgc caatgtttga accttatttt
    14161 ctatttcact atacttaata cctgctatca tataagtaaa aatatccgag tgctctgttt
    14221 gagggtcaat atggttcatc tcattaaatg taacccagta ctttacctta tcatcaaatc
    14281 ttcttattac agtctcactg tactttaaat acaaatctat aagttttctg ttattccatg
    14341 aaccatattt atgtactaaa ttcataggta attcaaaatg atatagtgtt acaataggtt
    14401 ctatattatt ttctattaat gtatctatca gaccttcata gtatttaatc cctaattcat
    14461 taggattttc atcatctcca tttggaaaaa ttcttgacca atctatagat attcttaatg
    14521 cactaaatcc catttcttta aataaagcta tatcttcttt atatctatta taaaaatcta
    14581 ttccattatg agatggataa tccaattttt cttctatttt atcagtaatt actcttggca
    14641 tttcataaga gcccttagtt acaaaatcca taattgcagg tcctttgttg tcactatccc
    14701 atgaaccttc acattgatgg gctgcaatac ttcctcccca gaaaaatgta tctttaatat
    14761 tcatgaattt tccctcctaa aatttatact attacagtta ataattcttc tgattcatca
    14821 tttgatgaga ttacatctaa ataatcgcta gtatttgtaa ctacagttat tatagtagaa
    14881 tcaaagcctt cctctataat tttatcagat tcaaatactg ctaaagcatc tcctttttta
    14941 accctttgat tttgtgttac aagactttca aagaattttc catctaagtt tacagtatct
    15001 atcccaatat gaattaatat ttctaatcct tcatcagtca ctataccata tgcatgttta
    15061 gttggaaata ctatagttat agttccatct acaggagata taacagttga ttttgattca
    15121 ctaggtataa ctccaacccc tttacctaat gctccagagg aaaatgcttt gtcattaact
    15181 tccccaagtg caattacctg accttttgca acatttccaa tactaatagt tcttgaattg
    15241 ttctcgttga ttattagttc taattctttt tcattatcac ccttaacttc ttctttttca
    15301 tctgaaggta ttcctagtaa ataggaagct gctgttgctg ctacaaatga tactactaca
    15361 cttattatca taaatgtaaa gttagatacc tctcctccaa caagatacgt tggtaatgca
    15421 gctaatcccc aaaccattcc atatgtttta acttgagcta aacctgctat taaaccacct
    15481 atacctccac ctatcattac tgctacaaat ggtcttctat atttcataaa cacaccaaac
    15541 actgaaggtt ctgtaactcc cataagtgca ctaaaactta ctgtaccaaa taattgtttt
    15601 tgttctttat tcctagtttt taagaaatat ccaaacattg caccacaaac tgcaatatca
    15661 gatattgttg cagcgcccat aaaaattggg tcatacccca atgttgtcac agaatttaaa
    15721 gatataggca tagtaaagtt tgctgcacca aagactatta agagtggttg taaagctgca
    15781 tacagtgcaa caacactcca attacccaat gtatcaatta aaaacataca tgcatagttt
    15841 aatccatcac caatccacat accaataggt ccaaatacag ttaatgtaac tgatagagtt
    15901 attattaaag ataatactgg aactaaaaaa tagtgtagtg ctttaggtaa tatttttttc
    15961 aaaccttcaa ttataattcc cattgcccat actcctaaaa gtattggaat aaaactgttt
    16021 gcataagttg tagactgtaa atttatacca aataaactta atccttctac accatctatt
    16081 gatgaagata ataacgtaac tgctaatact actgctatat atggatttac attaagtctt
    16141 tttgctgatg ctattgcaat taatactggt aagaagtgaa atgtagcact tcttaatgta
    16201 tctaatattt gatatgtagg actgtcactc tgaagtatgc cagacatatt taaaagtgct
    16261 aatatacttg caagtatacc agctgcaagt agtacttcaa ttactgaagt catagtctct
    16321 gagactacca caaagatgga attaaatata cctttgatac ctctaattcc cttttttctt
    16381 tcacttttta tacttgattc acttgaactt aaacctatca tagacataaa ctcgttatat
    16441 acatctacaa catgagtacc tattataatt tgataagcaa catcattaga aactacatca
    16501 attactcctt ttaatttttt aatttcttct gtttgagcga tactcctatc atttaaagta
    16561 aatcttaaac gagtaacaca atgcgctacc gactttatat tttcttttcc ccctataagt
    16621 tttattatat tttcatttaa atctttatat ttcatctgat tttgcctcca gtctttgagt
    16681 caccctattt atatgcaaca ttaaataagt ttcttcactt atagatatat cgacattaaa
    16741 ttgtgatttt atatattttc ttatcttttg aacacttcca aatgactttg gataaagttg
    16801 acttacttgt ttatataaat ctatagaatt atcttcatct attgaagctt cctctgacat
    16861 aattctttgg ataaagtact gtagatgagt agtaaatctc atataatttg ttgaagtttc
    16921 atctagctct acattaaaat gatattttat tatagaaact atatctgcta aagttctcaa
    16981 ctctacaatt gtactatcat gagactcttt atttacctcc atatttacaa aatgaagtgc
    17041 tattgatact gcctcatcat caggaagatt aattccctta ctatcaccaa ttaattttag
    17101 tgcatgcatt ccaatttcaa aatgctttgg ataaaatctt ttaacattcc ataccaaagg
    17161 actttttata aattgattct ttttacatct tttaagtaaa aactctaaat ggtctagtaa
    17221 ggttaagctt agataatcac ttgcctttat atttaaagtt ttctcaccat attcaattat
    17281 ttcattaata agaactatat tattggagtc tgagttttgt agtagataac taaagtgttc
    17341 tagcatatcg tatgaatcta gtatatatgt tctctctatt tcattttcat ttattacttg
    17401 tcccactctt tttttaaagc caattccttt aacaaataca ataatttcat ttttacctct
    17461 ttttactaag gctacattat tatttaaaat ctgaattatt ttcatatatt cctcccttca
    17521 ataaaaagaa ctcaagcata tatgtataga gtatccctct atttttcaca tatatacttg
    17581 agttctgcct gctaatcagt aacatactca aaattatgac tacgtcgcca taattaaaat
    17641 tcttttttgt ttaatttcat attctatatg ttatactatc catataaatc tgtcaacggt
    17701 ttcctagata tttttttatt ctataactac aagctctgtt atgcgattat ctgacaaggt
    17761 ttatatacta aattgatact attttaccgt cactagtatt tataatattg tctgaaccat
    17821 tatctatttt actattatga attatcatag taatgctttt aaatataatg aactgtattt
    17881 taacaaataa attcttaaga tatattaaca tataaagtct taagtttagt tttatttaat
    17941 cactattaag atatattaat aggtaaagct tcaaatttag tttcatttaa atgctagtaa
    18001 gatatactaa tatataaata cttaaattta gtttcattta aatgctagta agatatacta
    18061 atatataaat acttaaattt aattttgttt aaacactagt aagatatact aatatataaa
    18121 tacttaaatt taattttgtt taaacactag taagatatac taatatataa atacttaaat
    18181 ttagttttat ttaaacgctc tagtgatatt tttaaataaa ttttaataaa aattattcta
    18241 ttttgtcata aatcatttat ctggcttata tttaagatat attggtggat actttacact
    18301 ttttaattcc tcattacttc ttaaaagttt attattattt tccatatcat aaatttgtaa
    18361 cattacttta tttacatata gagcataata attatcacta taaaaatatt gatactcata
    18421 tcgagggtca tctttgtaat acactttgta tagtattcct tcgtaacttg ccttcttggc
    18481 tttttctttt gtaatacttt ttatattatc ttttgaaata tcttgtttta ccatatactt
    18541 atcaatatat gtttcagcat ctttccatgg tttaatgcag tttttatata caacaaaccc
    18601 tgttacactt ataataccta taattaatac tataaaaata actttatatt ttttcatatt
    18661 aatcctcctt catttattat ttaaaactcg atataatgca ctaaaaaaag gatgttatct
    18721 tttttattaa aatataacat ccctcatatt tagcatcaat atatatgccc caactggtag
    18781 gttaaaagac cccactgtca gtactttgat taaattacat gtatgtatat atatttttaa
    18841 caaatctatt atatgtcaac ttgtctacta ttacatataa tctgtaatat tacatctgct
    18901 gctttttttg agcctcctgc attataaaag ctttttgata gtttagttgc attttcttta
    18961 tattcattgt catttataac ttgaaatact gcttttttaa tactttctga tttatcctct
    19021 tttaacataa ttcctgctcc caaatgaaca actctcttag ctaccattct ctgctccgaa
    19081 tgttgaggaa ataataccat aggtactcca taatataaac tttcattaac actattcatc
    19141 ccagaatgag taacaaacac atcagttttt tgaagtatag caatctgttc aacactattt
    19201 ttaacctcaa aattatttgg tatatttcct aaacttttaa tatcagtact tctaccaaca
    19261 gacataatca catcaacatc agaatcttta aatgcattta tacagttttt ataaaagcta
    19321 acatttttat tattaattgt accaagcgaa atatatatta gctttctttt tctctcttta
    19381 ggttcaataa tcaactttga tactgatgga cctacaaatg aatacttact agagaaggtt
    19441 tctaccattg gttgaaattc ttttgatgta tatacaatgg tatccgtatc attatcatta
    19501 gaaactatag aaataaaatt ttttacttca tacccttttc tttgtaaaag ctttattttt
    19561 ttattaatgc gtcttacacc aaaaatcata cgtataattt ctataaagtt ttgtttcatc
    19621 aactttgctg tatgtttatt aaatgcaaaa gttgttgtag agcatacata tggaatatta
    19681 agtttttgtg caaataactt tccccaaaaa cttaatgaat ctgatacaat gcaatctgga
    19741 ttaaaatctt taagttctct acaaactttt tcatctaaag aaatagtagt atctactatc
    19801 atctcaatta atccaggaaa atccttacca atttttttct catctccagg gagtaattct
    19861 ggaaggtatt tatcacaaca aataaatttt gctccagcac cttcaatttt atctttaaat
    19921 tcattaaaag aataatacaa tacctcattt cctctatcca ctaattcacg aactacttca
    19981 atagtaggat tagtatgacc atatgcagga atgctaaaaa atactatttt actcatattt
    20041 catacctcct tttataattt ttttaaatca ttcttcttta tgtactactc ccacatgacc
    20101 tataaaattt atcaaatcac gttgatgaac aattcctaat cctctttcct catctccaag
    20161 taccaataat ttatctcctg catttatatt aaatacttct cttgcttctt ttggaatgac
    20221 aatctgacca cgttcaccaa ctacaactgc tccaaagaaa aactttcctt taggaggtac
    20281 tataatacct gttttttctt ccgaatgatt aactaagtca tctagtttaa cattgtacaa
    20341 ttttgcaagt ttaatgcaac tacctatatc aggaatagat tctccacttt cccattttgc
    20401 tattgattgt ctagaaacat taagtttttc agctaattct tcttgtgtat actgattgat
    20461 ttttcttaga ctttttaaat tctcattaat catatttttc atacctccta tgtttataat
    20521 attggattta ttatttaaat tctatcaact aatcttaaca ttcatatata tatttatata
    20581 cttttattat ataaatttat tgttcaggta acatatttcc ttaagttatc gtaaacaaaa
    20641 aaacaaacac aaatctacta actgttgtta aagtatttaa gttaaggtca tttacattat
    20701 caaatatttc tacaccttca aaataacctt tatatttata atctttcata agcaaattat
    20761 tatcccttct catatacaag tccagttgat gtcttgttgc taaatttaat ggtaatcaaa
    20821 ttctttacca ataagtataa aaattactaa tgtgttataa ttttcttaac tactaaattt
    20881 tacatacatt tgaatagaat atatcaataa attactataa taaataaaaa attaagagtt
    20941 aaaataaaaa atagttaggg agatattatt atgattttat attttagcgg aactggtaat
    21001 agccgatatg tggctcgtaa aattgcacaa gaattaaatg atgaactgat atcactaaat
    21061 caacttataa aagaggaaaa aacagatgaa ttaatatcaa cagataaacc attcatattt
    21121 gtatgtccta cttatgcatg gagattgcca atagtggtta cggattttat aaaagaaaca
    21181 aaatttctag gaagcaacag agtttacttt gtaatgactt gtggtggaga tacagcaaaa
    21241 tccataaact atattcaaaa actatgtaaa tacaaggaat ggcaattaaa aggtatggca
    21301 gaaattaaaa tgccagagaa ttatatagct ttattttcta caacagacaa agaaacatca
    21361 aaacaaatga ttaaagaagc agataaacaa atatatagga ttatttctga tatacgaaat
    21421 gaaaatgaat ttgaaattat tactcctagt ggcttaggag gtacaattaa aagtggtata
    21481 ataaatacag ttttttataa gacaattatt agtgccaaag gatttcatta tactgataaa
    21541 tgcattggct gtggaaaatg tgtagagcta tgtcctttaa ataatattaa tttaaaaaac
    21601 aaaaaaccag tttggaaaaa taactgtact cattgtatgg catgtatttg tggttgcccc
    21661 actgaagcta ttgagtataa aaataaaact caaaacagag aaagatacta tttagaataa
    21721 tatattctta atatttaaac cattataaaa tgaactatac ccattgtttt atacagtttt
    21781 acatatttta actgtctcct aagatgggta tagttcaaaa gatagtgtct caaagtgaac
    21841 tttttagttc tttttagttc ctaaatcaat ctttttgtat taaatcaagt ataatttaat
    21901 caccttttct tatatcattt tcactaatat gttgtattcc aacaaatata agatttatta
    21961 gctctgttag tgacctccat tgtgattttt ttgaatcaag ataataataa ttttttgttc
    22021 cttctctacg caaattaaca atctctgctt cttttaatat cttaagatga tgagatacag
    22081 caggacgaga aagatgtgtt ttttttgtga tttctcccac tcgtatacca ttaaaatcac
    22141 tctctaagag agcaattaaa atcaattgtc tagtctcatc acccatagca gagatagctt
    22201 tgcgacattc tttaaattta gacgttattt cttgcattct ttgttgacat tctttttcca
    22261 taaaatccac cctctcttat aagtatctaa cagttgctac ttctttctgt gcagtacgtc
    22321 tatatttaac atctgggtat ccaattacta atgttgtaag aacatgatta ctgcgtttta
    22381 gacctaaaag cttttttaat tttggcgaat tatttgctac atctgaaaaa tatccactaa
    22441 ataaaacacc taggccataa gactctgcca ttaatgccat atttgatgct gcaagtgaac
    22501 cactaatctt atcttttgta attatcatta ttgcaatagg agcatgctta aagaaaaagt
    22561 tatcgtcaat ctcaacttct tttgaatatt taatagctat atttgcaata ggttttattt
    22621 ttctaaaaaa tttcactgct tcgttttcat aaattgactt tttattgtct aaaacaatat
    22681 atgatacatc ttgtgaattt ttagcactag gggtatacct acctgcctca ataatttgct
    22741 ttataatttc tgaagaaact tctttgtctt taaatttacg tatacttctt ctagatttaa
    22801 ttgccattag taattcatct gaatctagct ttggcttatt tgtaagttct ataggaggtt
    22861 catcaaatcc tgtcaaggta atagcttttg tgggacatat tgctgcacaa tgtccacaca
    22921 ttagacaatc ttgtttttta attactgact ttttattttc tataattata ttgtttactg
    22981 gacaatcatt tttacaaagc ccacatccaa tgcaaagttc tttgtcaact tctattatat
    23041 gttggtattt catattcatt catctacctt tcgtttatta gtttaaacta ttataacacg
    23101 tagacatttt ttatattcat tggtaaagaa tttgattacc attaaatttt taatttctct
    23161 attaaataaa tttttcatag aattttaaag tatcatagtt tatacataat aaaaaagaca
    23221 agcttaaaac ctaagcttgc ctttttcatc ttttattaca aagtaaattg cacttacttc
    23281 ccatacttct taacaatttt attttctaaa attttatttg tgaatcatac tattgcataa
    23341 atacaatgta aaataattct gtattgattt tctatagtta aaaaagttaa aaattatact
    23401 tattattaat ttttatactc ttcttattta atacaaattt cttatttaac atagatttct
    23461 tgtctaatat aaatcttcac catttgaagc aattactttc ttataccatt caaaactttt
    23521 ctttttcatt cttcttagac ttccattacc actattgtct ctatctacat atataaatcc
    23581 ataacgcttt tccatttcac ctgtaccagc acttactaaa tcaataggtg cccatgtagt
    23641 ataacctaat aaatcgaccc catctataga aactgcatca tgcatagctt ttatatgttc
    23701 tcttatataa tcaattctgt aatcatcttc tacataacca ttttcatcag ctatatcttt
    23761 agcacctaat ccattttcta caacaaatag tggcttttca tatctatcat atacatgatt
    23821 tagtgtaatt ctcaaaccta atgggtcaat tggccatccc cattgactgt atgaaagata
    23881 tggattttta gcagatgtaa atatgtttcc ttcagccata tcatctgcat tttcatcggt
    23941 tctaacacaa cggctattgt aatatgaaaa tgaaataaaa tctactgtat atttattcaa
    24001 taattcaata tcaccaggtt ccatttctgg tgtaatacct ttttgctcca tatactttaa
    24061 cgcatagtta ggatatttac ctttagattg tacatccaca aagaagtaat tttctctatc
    24121 taactttgta gcttcccata catcattagg attacaacta taaggatata cacttccagc
    24181 tgcaaacata catccaatta agttatttga atcaacttca tgtgctattt tagttgcaat
    24241 tgcactagct acaagctcat gatgggcagc ttgatatttt atcttttcaa catcttcacc
    24301 ttcttcaaag caaataccag cacccataaa tggagcatgt aaaatcatat ttatttcatt
    24361 gaaagttagc cagtacttca ctaatccttt atatcttcta aagataacat tgcataattt
    24421 ctcatagaaa cctatcattt ttcgattacg ccatgcacca tactttttaa ctaaatgcat
    24481 tggacaatca aagtgtgtaa tagtgactaa aggctctatt ttatattttt tacactcctt
    24541 aaatatattt tcataaaatt gaagtccctt ttcatttggt gtttcttcat caccttttgg
    24601 aaatattcga ctccatgcaa tgctcattct atatacttta aatcccattt cagcaaataa
    24661 ctttatatct tctttataat tatgatacat atcaatacca gttttagctg gataataatg
    24721 ctcatcatca aaatcaaaca tttttagttt ccctgtaata actgctgttc tatcttttcc
    24781 tgttggacat acatctacat ttgccaatcc tctttcgtct tcattgtatc caccttcaca
    24841 ttgattggcc gcagtagctc ctccccataa aaaatcattc ttaaaactca tagtcaaagc
    24901 ctcctaaaat tataaccaaa gcactagatt atgctaatac ctcaatcttt actaaaataa
    24961 gactgtaatt agattgtctt ctaattcaat atttttactt tctgtttcta ctacatctaa
    25021 aaattgtgat gaatttgtaa taacaattgg agttacagta ctatacccca actcttttat
    25081 tgcatcaaca tcaaagttta atatagtttg accttttgta attctatcac cttgttttat
    25141 acatgcctca aaacctcttc cctctaattg aatagtattt aatccaatat gaataagcac
    25201 ttcaacacct gtatcagaaa gaatccctat agcatgtaga ctaggaaata aggttgtaac
    25261 taccccatct actggagcaa ctacttttcc atcactaggt attattgcca ccccttgacc
    25321 tagtacacca gatgcaaatg ctgcatcctc tatatcactt aattttaata cttcaccttt
    25381 tataggactt gttactattt ctctttctaa tttagtagac ttgacttctt ttatttcttc
    25441 tttaccctta tttcttactt ttttagactc ttctactttc tcatctttat ataaaatcat
    25501 agttaataca aaagctacga ccattgatat agctatacca gaaagagcta ctattaagtt
    25561 acccattccc ccatctggtt caatcattgc tggaagttca aatattccca ttcctccagt
    25621 tataaatttt ctaagattaa agaatccata gaaagcgcct ccaataccac tagcaataca
    25681 acttattata aatggtttct ttaaaggcaa taatattcca taaattgctg gctctgtaac
    25741 tccaaatata ccagatataa agtttggtat tgccatctct tttagttttt tatctttagt
    25801 cttgaaaaat attgccaaca caactgccga acttgcaaat gtacaggcaa agaatggcat
    25861 cataacatta tcatatccta aagtcataac attgtttata tatacaggaa taaatcccca
    25921 gtgcatacca aaaataacaa gaatttgcca agtaaatcct actatagcac ctgccaatag
    25981 tggactaaaa tctcttattg aaattacaat ttgtgaaata agtgtagaac caaatgttgc
    26041 tatagggcct ataactataa gtgcaacagg cactgttatt aataatgtaa gcattggcac
    26101 aaagaaaaac ttaactaaat ttggaacaca cttattaaat aatttttcac acctagaagc
    26161 aaaatacact ataaatataa ttggtacgac tgttccagta taatcaattg atacaattgg
    26221 tagtccaaag aaatcaatat atactggtga tgcaaacatt gttcctttaa ataaagtgta
    26281 catcacatct gctcctgctg atatactgct accttgtata gcaggataac atactgcagc
    26341 tcctagtgct aatcccaaca ttggttttaa tccaaacttc ttagctgaag tatatcctaa
    26401 gaacaaagga aggaatgtaa ataatgcatc tcccgctgca tttattacca tataaccacc
    26461 agatacatca ctatataatc ccattgctac aaataatgca ttaaatcctt tcaacatacc
    26521 acaagctgcc attattccta acactggctg aaaaattcct gatattatat ctataccttt
    26581 atctagtata ttacctgatt ttttagtttc tgaacttgta cttgaatcat ctaaaccaat
    26641 tatttcaact acatctttat agacagcttc aacatgattt cctataacta cttgatattg
    26701 tcctccactt ttcattacag taacaatacc ttccatgttt tttaatacat tgtcatttgc
    26761 tatactttca tcttttaaag taaaacgtaa tcttgtaata cagtgtacta atccactaat
    26821 attttctttt ccaccaacat tgtttactat ctcttgtgct aattgtttgt attttcccat
    26881 ttttctcctc catatttcgt ttaaattaat tttttgaaat ttgaaggttt ggccaactca
    26941 atgttaccat ccaaccataa gtataatttt gttagtatca ctcctttcaa tcattcttaa
    27001 tatactgctg aaaaattatt tcacttacat atttgagtct ttaactactt tagctaaatg
    27061 tattgttaaa tatataagct catcatctgt taatatgtag ttatattgtt ttttaatgaa
    27121 atttttaatt ttaactacac attcaaactc tttattatat ttagatttaa taatgcttag
    27181 taattctttg tctgtctcac cttcatgtgc actatctaaa agcaatcttt gcgcaaaaaa
    27241 ctttaaatgc attataaatc tataataaaa cactgattct tcatgaaatt ctatcctaaa
    27301 atgataccta actatgctaa gtacttcttg tattaacttc gtaatatcag atgccaaagt
    27361 atgaccttca cttaactgag cattcactat atgaaaggct ataaatccag cctcatcttc
    27421 tggtaatttt atacctgttt tgttttcaat aatatctagt gctttcattc caatttcaaa
    27481 ctcttcttta taaaatcttt taatttccca aaggattgca ttttttacat ttattccttc
    27541 tttcattctt tgaattgcag aatatgtatg gtcacttaag gatatgtaaa tacttttatt
    27601 tagcttcttg tttaacttta tttgtgcgta ttctataatt tcacttgata atttcatgtg
    27661 ttctatagga atattattga gtaattcttg tagtttgttt gatatttctt tatttgatat
    27721 tctaaatact ttatttactt tagttttatc tattagattg ccttttgatt tttgataacc
    27781 aattccttta cccataacga taacttcttc atcattatca tctaatgtga ttacaacatt
    27841 attgtttaat atcttattaa ttatcatgat tatcctcctt ttaagcataa aaaaagctta
    27901 tccataataa tgggcatact ccttcctagg atactgctat tattaatgaa taagcttagc
    27961 ttgtacttaa acaattacta cctaattcca attaatatga taaaacatca gacatatttt
    28021 gtcaactttt tatttccata tacttcatca atcttttatg ttgctttttg tcagttataa
    28081 taattattct tattaatatt aacttatttc tttgcatcaa tataaataca aaacaagtta
    28141 tagtcaataa taataaaaat tctattaatg taaatagtta atattatact tcctctacta
    28201 cattatctgt actttattta acattttttt caactccaaa aacatatgtc ataataaatg
    28261 gagcaaccaa tgctataaat ataactataa gtccatttac tatatttgaa atcccctttt
    28321 cccctgataa tccaagtact gccattatac tattttgtgg aacatataaa gtcacatgag
    28381 taattcctgc aaataaccct gcgattcctg ctcctataga tgctaacata gcaggttttt
    28441 taagtttcaa tgtaactcca taaagagctg gttcagttat acccataata gctgatatcc
    28501 atgcagctga tgctaactgt ttcatcttac tatctttgct tcttaatgct acagctaatg
    28561 ttgcgccacc ttgcgctaaa ttagcacaaa cttgagatat taatattagc gattcttgtc
    28621 ctgtagttgc aaatgctgat atgaatatag gagtcaatgc atgatgcatc cctgtcataa
    28681 cgataaatgg cattgcagct gctaataaac aaaccattat aaatcctaac cttccttgta
    28741 gtaaatttat tatactagct aatccctctc ctaagaaatt tcctattggt ccaattacta
    28801 ttaatgctat tggcgcactt attaataata ctaaagttgg atttaaaatt gtttttaaca
    28861 tgctaggtgt taatttatca atgaaatttt ctatatatga catcatccat actgttaaaa
    28921 gtgcagggat aacagatgct gcatatataa caccttgaat tggtactcct ataaatgata
    28981 tagggtcccc acttgatacc catgcagaga aatttggatg taaaaacaca cctactacta
    29041 taactgctat tgatgtatta acattaaatt ttttagctgc atttattgca agtattatag
    29101 gcataaagta aaatgctaca tctcctatta tatctaatac tctatatgta cttgaatttg
    29161 atgatagcca attaaaagtg gtgcaaagag ataatataac ttttatcatc ccagatgctg
    29221 taagggctgg tatcataggt gtcatacaac cagttattgt atctattata ttatttaaaa
    29281 tactattttt tttattttta ttttttatat cgcttttaat atctcctgtg gtatttatcc
    29341 ccttatttat tattgcatta aatacaacac ctacctcatt acctattatg acctgatatt
    29401 gagttgaagt tgagtttact ccaactacct tatctataga ttttaattta tctgcattga
    29461 ctttcttttc atcttttaag atgaacctta atcgtgtcat acaatgagtt aagtcaatta
    29521 tattatcttt tcctccaagt ccatcaatta tcaattgagc tacatcttca tatttattct
    29581 tcatacctta tcctctcttt taaaataatt tttaatataa ttttaatcca aattaatctt
    29641 tttactccaa gcttgtaata gtgtattgta atttaataag ctagtatctt ctacaatatg
    29701 gtcacatttt cctagtactt cttttttccc cacaccaatt gatgtcatat tggcagcatt
    29761 tatagcttta atacccgaat aagaatcttc tattcctaca caatcatatt gttttaaatt
    29821 tagcatcttg ctcccttcaa taaaaatatc aggatatggt tttccccttt ttaataaaga
    29881 tggatttact atacaatcaa attcatcttt tactcccaaa gattctaata tcctaggtgc
    29941 attcttacta gcagatgcta ttcccaattt cacattattt tttttaagtt cttttataag
    30001 ctcatttatc cctggtaata tatctttata tgttaatgag tttattaact ttatataaat
    30061 gttatttttt tcttcacaca cctttaactt ttcctcttta gtataactat ctactttatt
    30121 agcagataac aatattttat ctaatgattc ttccctgttt atgcctttta atttttcatt
    30181 aaaagtttca tctatttcta tatctagcga ttttgctatc tcatgccaag cttcaaaatg
    30241 atacttagca gtatctgtta taactccatc aagatcaaat aagactgctt tcatattaat
    30301 tactcccttt aaaacaatta ttaacttcta ttatgttctt tgataatttt atttctttat
    30361 tatcatgtaa tatggttata tttctacctt tgattaactt ataataagat ttatattctt
    30421 ctatatttac aaaaactaaa ttatctctaa ataatatatt aaatttaata tttttccagt
    30481 gtttaggtat ccttggttca aaacttaatt tatcattttt tattttcatt cctgcaaatc
    30541 catatactaa actcatccat gttccaccca tattagcagc atgtattcca tcacttgtat
    30601 ttttttgtag gttattaata tccattaatg ctgtgtccat aaaatagtta taagcttttt
    30661 catgatttcc aatttcactt gccatcattc caaatattga ccttgacaaa gatgaatcat
    30721 gagtagttat tttttcatag tattcaaaat ctctcttctt ttgttctaag ctaaactcat
    30781 cagggaaaag caacgctgaa agtacagtat ctgcttgttt atttacttga tatctatata
    30841 ttgttaatgg atgataatgg agaagtaatg gatatttttc ttttggtgta tttttaaaat
    30901 cccatactga tttttctaaa aatgaatcgt cttgtttgct tattttcttc tcttcatcat
    30961 atggtaaata catattttga gcggcattta tccagttttt cacttcatat tcttgtaatt
    31021 taacttttct aaatacttca tttgaaaata aattatgctt aaatttatct accatctgta
    31081 ctgcatatat taaattatac ttagccatta aattagtgta gtaattattg tttactattg
    31141 ctgtatattc atctggtcct gttactccat ttatacagaa tttattattt tttgattcta
    31201 tataatctcc aaattcaacc caaaatcttg atgtttctat aagaatttct aagccatttt
    31261 gcatcataaa ttcttcatca ttagttgctt caaaatacgt tctaacacca taagctatat
    31321 ctgcatttat atgaaactgt gctgttcctg ctggataata tgcactgcat tcattaccat
    31381 ttatagttct ccatgaatat aagcaacctt tatttattcc aagttctcta gctctttctc
    31441 ttgatgcatc taagattgag tatctataat ctaataaagc tctagcaatg gatggttgag
    31501 tatatataaa aaatggtaat atatacattt ctgtatccca gaaataatgc ccctcatagc
    31561 catcacctgt aagacctttt gctgatatat tagtctttcc atctcttcct gctgattgat
    31621 aaatatgaaa taaattggtt tttatcccca gttgaagagt tttatcgcct tcaatctcta
    31681 catcagaggt tgtccaaaac tcattcattt tctttctctg aatatttttg actttatcaa
    31741 atccaatatt acatgcttct cttaaaacca attctaatga ttttaaatgt gcttctgatt
    31801 ctaaacattt taacgactcc agacattcta atgattttaa acgttcttca tttagattta
    31861 aatcagaata tactctacta tagcctacaa caatttctaa atttaacctt tcatcttttt
    31921 tggcatagac ttctatttct cgctcaatac attcatctga aacattatag gtctcatttg
    31981 taatatttcc acaagtaata tatgaatcaa acccacacca taaccctaat ctacttcttt
    32041 ctgtaactaa attcataaaa tacttattgt tatatttttt tacattaatt ttaaattgct
    32101 tcttatttat agatgccact cttgggtcat ctactttttc acaattaaac ttctccatac
    32161 tattttccat tttattttta aattttattt ttccattaaa attcaatggt gttattgtat
    32221 atgaaatcat cattaattct tctatatctt gtgatactaa tctttctata gatactttaa
    32281 cttttctacc acgagagttt tcccatataa atgaacgttt aagaatccct tcatttaaat
    32341 ctagtatcct agtatgttca cttgtaatac cttttgataa atcaaagcaa tctccttcaa
    32401 tagagaaatt tactatatga gcattaggta acttacagat agtctgattt tgttttgcat
    32461 agccataagc gctttctcca tatgtaattg gagattcttc ataaaatcca tttacatatg
    32521 tacccatatt atctacatac tcattattaa aatcagactc ttcaatattc cctctaactc
    32581 ctaaatgtcc attagctagt gtaaacaacg tttcattgga ttttattgta tccttactaa
    32641 accctagctc tacaagttgg tccttagtag taaatattaa actcataata acactccttt
    32701 cttaaaatga attatgcatg agtttccata tcattaaata aaatttctcc atctgtttct
    32761 attacttttt tataccaaaa agcactttgt tttttagttc ttttaaatga gcctcttcca
    32821 tagtcatcag aatcaacatg aattatgcca tatcgttttg tcatctttcc ttcacttaca
    32881 ctggttacat ctatacatcc ccacataaga tatcctataa gctctattcc atcttcattt
    32941 actccaagaa tcatattttt aatatgttct ttcatgtaat ctatacgata atcatcaatt
    33001 atttttccat cttcatttac aatatcttga gtacccagtc cattttctac tataaataaa
    33061 ggtaactgat acctttcata taactgattc atagttattc ttaaccctac agggtcgttt
    33121 tgccatacac tatttgattt tggaagatat ggatttttta tggtttctgg tccgtttgcc
    33181 tttgattttt ctaaaccttc agctctagct gaactacaag cactagaata atagctaaaa
    33241 gatacaaaat ctacagtatt atccttaagt gttgataaat cttcctcttt tattattaat
    33301 tttatttgat ttgattttaa ataataactc ataaagcttg gatacacacc cctaacttga
    33361 acatcagaaa aaaacaaatt atgcctctca tgctctaaag ttgcaaatac atcttctggt
    33421 ttacatgtgt atggatatgt ttttccagca gctaacatac acccaaactt aaattcttta
    33481 tttatatacc ttcctatttc tatagttttt gcattagcta ataattgatg gtgtgctgct
    33541 tgatattttt tctgaagttg attttcatca gctataaaag ttaacccagc acctatatat
    33601 ggaatatgca ttatcatatt catttcgtta aaaggaatcc agtatttgac atcatcttta
    33661 tatcttttca tcaaaatttc agcatatttt acatataaat taaccactct tctatcagcc
    33721 cacccagaat atttttcaac tagagaataa ggtatatcaa agtggcttat cgttattaat
    33781 ggctctatat tatatttttt taattctttt attatattat cataaagttg taatcccttt
    33841 tcatttggtt cactttcttc tcctgttggg aatattcttg accaagatat agaaaatcta
    33901 aaacatttaa aacctatttc tgctaacatt gctatatctt ctttgtaatt ttcacaaaat
    33961 ttaatcccta tatgacttgg atagtattga ttattttcat ttaaaatatt atcctcatct
    34021 aaacatacat tttttaatct cttatcattt aatgggagtt tatcaaactg agataaacct
    34081 tttcctccat ctaaataaaa tccttcactt tgattggctg aaattgcccc tccccataaa
    34141 aaatctttcc ctaatttcat gcatctacct ctttcacagt ataaaatttt ataatttcta
    34201 tctcatattt agttataaga tttttttcat actatacctt ttaaataatt caatttaaaa
    34261 atccaattat attttttact cactataatt aatattgtct attttcaata ctttcatatt
    34321 aaatatcaat attagatatc tatgtatata attatatata tagcaaatac atttttatat
    34381 cctcattatt gttatcttat tctcatatat tgctgtatat ttatatatat aaaaggattt
    34441 atttcgaaat agaggttgta ttgagaacta aaatttagac tttataaatg aatggaattt
    34501 tcattgttga aatactgaaa atatatttga tttcatataa aagaaagtgc ctcatgaact
    34561 aagttcattt tgagacactc ccttttttct ccaagctatt atatcttttt ttaaattcta
    34621 atggagagac tccaattttt tctttaaata ctctgtaaaa agtttttgta cttccaaaac
    34681 caacttcttc aaccaaatct acaatggata tattgttatt aagtaatatc cactttgctt
    34741 tttctaatct atattcattt aaaaaagtta taaatgtttt tcctgtattt tttttgaaaa
    34801 atttagtaaa ataatataca ctaaatccta cttcataaga cacatcttct aattttatag
    34861 gttgtttata atttttttct acatatttga atatattgtt caatctctct aatatctctt
    34921 tagagtttat ttcatattct actgtatttt cttcaatttc tctaggaatc tgtctatata
    34981 atataggaat taaattatac attttacctt ttattgcata actatatcct tctattttgt
    35041 ataggtcttc attgtagata tctatcaata tatcgaaaac tgactttctt atttttgctg
    35101 accaatctct actacatttt tttatactac tgaataaatt aattaagctt tctttctcct
    35161 catttaataa aattaaatca ttaaaaaaag atatatcaaa ttgaaatact aatctttcac
    35221 ttcccggtga tggcagtata taatgaatat ctcctccttt tattatcact atctcgcctt
    35281 tttttaattg cataggcttg tcatttataa atagatttac tacaccttct gttataagta
    35341 atatttctat ttccttatgc cagtgtggtg ttgttaatac ttctccttca tttgatagag
    35401 tacgaaaagg aaattcatgt attaatttag gcatttctaa atatattgcc atatatatcc
    35461 tctcctctct agtgtctaaa aattaatcta tactatttaa aagaatacac attttatttt
    35521 aaaaacctca aatttataat ttatacaata cctacacttc ataaaatata tctaatattt
    35581 ctttttttgt atgtgcattt aaaagtcttt cacctatatt tttaccacct aaaatgtaag
    35641 ctattttaga tattaatatc atatcttcat tacctccaga ttgtggcata gcaaacataa
    35701 ttattacctt tacaggtaag ccatctatac ttggccaatc tacacctttt ttagatttac
    35761 ctattactat ggatgccttc tttacatatt ttgtttttcc atgtggcatg gccatttgat
    35821 aacctatact agtagagcct attttttctc tatgttttaa tgcctttata aacttacttt
    35881 ttaaagttat acttcctgta tcgtataatt tatctactaa ttcctgtatt atgccttctt
    35941 ttgtagttga tttcaaatct aaaataatgc tttcttctgt taatatttct ctaatttcca
    36001 tttgttttct ccaatagatt attcttaaat aatattttaa tatcctcttt gctcttgcaa
    36061 tctattatat agtttatata gttcttttgc ctatataaat ttgatatttc cattaaaata
    36121 ttctttaaaa aactttgatt actaatttct aaataaatat caatcgttct agtaacatta
    36181 ttgatattca ttatcccttt atttaattta ctttgcttat gtatatatat atttaaatct
    36241 tttcctaatg aaatagattc atatttactc cctaaattca cacctattaa actttccatc
    36301 tgagctacat caaaattaaa atatatatta tcttctaaat acattcctaa taagtttgta
    36361 tctaagttca tacttttttt aggtttagaa agtaaagcat tttttatatt attaatatca
    36421 ctttccatta atagtactga tacaactata tgtaatttat ctttcaaatc taagtttaca
    36481 gtagatatta caaagtctac atcatctaaa tttcgcttac tcaactgatg cataggaact
    36541 atatcaacta tagtccattc aggaaattct ctttttaatc tggctgcaag gagctgagat
    36601 gttccatatc ctgtatgaca aactactatt actcttttac tactcatatt tctttctatt
    36661 gccgcttgaa aatatgtggc aagatacgaa acttcatcta tactaatatt cttcagatta
    36721 tcatactctg tcataatatt tatagtcatc atacataatc ccagcacatc tgaaaatcgc
    36781 tcttgtatct ctcctaacaa cgggtttttt atttggatat catatcttaa tctgtttaac
    36841 ataggcctta catgagatgc tagacttttc tgtagtaagt catcattttt gagatttata
    36901 tttaaaaatc gtgacatatt ctctatcatt atagatgaaa ctttttcact ttcacttaat
    36961 ctatctgatt catcattgta actactatta ttttcgctac taaatccaga tgataccaaa
    37021 aaaatatata tgtacataat ttcatctttc gttattttta ctctgtatct attttctatc
    37081 ttatctataa gtgtagtgac atttttatat actaactcgt ccaaattatc tacagaaatt
    37141 tctctttctt cctgagattc tatttgatta ccttcttcga ttctctttaa acatataagt
    37201 atatgggtaa ttaaatttat atagtagggc tgatttatag tatatcctaa attgtattct
    37261 aattctgtaa ttatagtttc tacaaatata atagaatcaa tatcaaataa atttatcaat
    37321 gcactaaatg tagcagaatc taatcttgtt aactcagata tatcatgttg ttcataattt
    37381 tcatctaata aatcatccat cattttggca atcgatttcc ttatatccac ttctttacct
    37441 ataatcttag ttccttctaa agttttatta agttttaaat tgtattcttt tatccatgcc
    37501 tctatatatt taaaatcatt tactatagaa gttttactta cataatattt atctgctaac
    37561 tgatttattg aagttatatt atttgaattt agcaataaat actttaaaat ctccattctt
    37621 ctctgctcta ctgataaaga tttattttcc ttcgattgta tatttaaact attaattaag
    37681 tctatgttct tctttgctaa atcttctatt aatattccat agcctctttt tatatcaatt
    37741 tttatattaa aagtttctaa atatttctca atcatcttca aatctttttg taaagtttta
    37801 tcagatacat ttaatttatc tttaaagtat tttataggtc tatatttatt ttcgtttagt
    37861 atcaatttaa gaaattcaat ttgcctcgac acaagcatac ttagccctcc ctacctatgt
    37921 ttatatattt ctatgtttat attaagtact attttaacat atttactaac tatgtaaaat
    37981 tactaagata cttctgtatc ataaaagaat ttatgataca ccttactaaa ttgatataat
    38041 agataatata atttcaaaat aaaaattaag gatatttaga aatagttaac tgattctaaa
    38101 tatccttatt attattctat atacttgttg ttattccatt aattattttt actattattt
    38161 ataatttaag caccaagtaa ttcaacttca ctattttcac tccttatagt aggctttgtt
    38221 acccctataa tcaatgctgt tattactgta ccaatcaata tacaagctat atatgcaact
    38281 ggtgcactac atgcaaatgg tattacaaat attcccccat gtggtgccat taaagttata
    38341 tctaaactca tacatattgc cccacctata caagaaccaa ttatatttgc tggaatcatt
    38401 cttaatgggt ctgcagctgc aaacggtatt gcgccttctg ttatgaaaga tgcccccatt
    38461 atagcagttg gtagagatga ctttctttct tctttagtaa acttattttt gaatattaac
    38521 atagctaatg atattgctaa tggaggtacc attcctccta ccattaatgc tgctgatggt
    38581 tcaaatatat tacttgaaaa catagccaat ccaaaagctg aagctgtttt attaataggt
    38641 cctcccatat ctgatgccat catccctgct aatattgcac ctaataatac tttattagtt
    38701 ccagacatac tttgtaacca agattgtaaa gcttcattta accatgatgc tggcgtatta
    38761 actacaaaga acattatagc tccactcgta aatgcaatca aaagtggaca tatcaataca
    38821 gcatttactc cttttaatac atctggtaaa ttttctgtta tcttcattac tcctaaagct
    38881 atatatcctg ttgcaaaacc agctaccata ccacctataa aacctgaacc tccaataact
    38941 gccataaaac cagctatcat agcaggagca aatccttgtc ttcctgctat tgatttagct
    39001 ataaaaccag caagtatcgg tataaataac ttaaatgctg aatcgcctcc aagttgtcca
    39061 aagaatccag ctatagggtt gtatgtttca tgagttgggt ctgatgcaaa tataccaaac
    39121 ataaaagcta tggctatacc aattccacct atcactacaa atggaatcat ttcagataca
    39181 ccactcatta agtgcttata aacacccttt ttctctgacc cttgaagcat ttcttttgaa
    39241 tcttctaaag tctttccacc tggtttaatt tctttagcca ttccattttc agcgtttata
    39301 attaaatttt tagctaatga aacattctta gcatctacta ctttcttttg tagcactttc
    39361 tttcctataa atctactcag ttgaacttct ttatcacaag ctattattac gtattcagct
    39421 ctttttatat cttctttagt caacttattt tctacaccta tagctccatg agtttctatt
    39481 ttaacttcat atccaagttc ttgccctgct tcctctaatg ctttttttgc cataaaagta
    39541 tgagctatac ctgttggaca tcctgttatc ccaactataa gacctttatt ttgattatta
    39601 ctaaaatctc ctgattctgc agctttatta ttaaatatac ttaatatttc gtatggagtt
    39661 tctgcactta gtagatgctt aagaaaattt tcttccatta gatatgtagc tagtttagat
    39721 ataatcttaa gatgttcatc tgaacctgat tctggaactg ctatcataaa aaatgaccta
    39781 agtttttgac catcattatc tgtaatctct ctatctgttc ttaaatacat cattacaggt
    39841 tgatttacta catttgactt agcatgaggt atagctatta aattacccat attagttgat
    39901 gattcttttt cacgtttatt aatatcagct ataaactttt ctttattatt tatataattt
    39961 ccatggtaca aatgatttgc catataatta atcacatctt tttttgtttg taattgttta
    40021 tctagtacaa tacaatcgct tcgtagtatt ttacctatca taaattctcc cctcctttta
    40081 atttgttacc tcataattaa tttttatttt tataaaagca ctttaactta tctatagcat
    40141 tgaatagatt cattttaaac tctataactt ctcttgcagc ttttatacat ggtggatata
    40201 tagtatctgg ctcatataag cttgggtttt gttctaatag ttctctgcac ttcttataat
    40261 atgccgactt aacatcactc gaaatattta ttttacaaac tcctagttta actgcttgtg
    40321 ctatttcttc atctggattt gatgaaccac catgaagaac taaaggtata tctactactt
    40381 ctcttatttc ttttaataaa tctagtttaa gctctggttt aaaacctttt ggatatatac
    40441 catgtgctgt accaattgca atagctagtg tgtctactcc tgttttttca acaaaatcct
    40501 tagctaattt tgaatctgta tatattattt catcagtacc accttcactt gatgttcctg
    40561 ttgttcctat tgttccaagt tctccttcta cggacacatt taatcctttt gctatttcta
    40621 ctatttccct agatatagct acattctctt catatggtaa atgtgagcca tcaatcatta
    40681 ctgatgtaaa tccacatctt attgccctta atatttgttc tttattttcc ccatgatcta
    40741 agtgtattac cataggtact ttactcttat ttgcttcttc tatgcaacta gctacaaagc
    40801 tatctcctag aaaacttagc tcatttgggt gtattgcaag tattactggt gcattttttt
    40861 cgttagcact ctgtactact gctttaagta tttgcccact tcctatatta aatgctggta
    40921 cagcaaattg attttcttgt gccactttta gcatttcctt catgtttatt aacatattgt
    40981 acctcccgat attttaaatt ttaggttgaa tttgcttctt gttaattttg ttgttgttta
    41041 tatttaaata atatcagggt aatgaatgtc agaaaataac aatcgttttc cttagtgaaa
    41101 aggaactttt attatacact ctaagttcct tttcactaaa taatttttag aagtctgcat
    41161 catagttaat tatatttctc atgtacatct tctcttttta agtgttttat gctttagcct
    41221 tcctagattt tataataaac aattaagata cattaactat aaatttaaag atactcatgc
    41281 aatagttaat gctatattag agtcaaaaaa attaaaaaga tattagctat ttggccaata
    41341 ccttttcttg gattccaata gtatatacga tttatagaaa tcttactcac gattatctaa
    41401 tgttttactt ccataaactt tacataaaac accaaagtga caccctccaa attcatctct
    41461 agctaataaa gtgatttggt tttctaagca ccaatttata aattagcctt tgttatctta
    41521 tgtaaatctt tttctatcta atttaaaaat tattcctaat gctatatagc atataccaat
    41581 tactaataca ccataagcca tagatactcc tatcttaaat tcttgcatat taattacaat
    41641 agaaactgaa atagatttat tacaaacacc ataaagcaag gctgacattg tatattatcc
    41701 aattgtatga atgaatacta atatagctcc ttttaattaa atgatgctat ataaatcata
    41761 tttatcccaa tttttaatct aacctattta tatgtatatt cctttttaat aaaaaaagat
    41821 attgactaaa tagtcaatat cttttagttg atttaaatac ccacaatttt aatctaattt
    41881 ttaagtgttt ccttaacata atcttataaa tattaaaatt tatctaccta taaaatttct
    41941 ccattaaatt ttattacatt ttatcttaaa acaattataa tctgacctta atcatatatt
    42001 atattatata aatattttta acaaacttaa taattaaata actatatttt attatccatc
    42061 ttataaatgt ttataaactt tccactattc ttcttcaata aattcaaaca aattttctac
    42121 tgtagtatcg aatactttag cgatatccat agctaacttc aaagaaggat tatatttccc
    42181 attttctaag tgtacaatag tctcacgtct taccccaacc aatttagcaa gttcattttg
    42241 cgtcataagg agtttttctc tgtattcttt aatttttgtt ttcatcaata ttgccactta
    42301 gttacatatc ccccttttat caaagtatat atacaacact aatttagata aagactgtat
    42361 aaataaaact gcaatgagga ttatacctgt atctaggttt gatatattta tattacttgt
    42421 ataaggtgtt gcaaagaaaa tagatattat tactatagaa tatatcatta tttttattgc
    42481 aatcttatta acctttgata gtataaattc agatgattca tcaactaaat cattatattt
    42541 tttattataa attgaataac atccaaaaac tattaaccaa ctcaaccctg gaagagaagc
    42601 agtgcttgga cctttaaaaa tatacttagt ggctaataca gctataaaaa aataagttat
    42661 tacaagcaac tccaggataa gctttgatct tacaccagtt tctgatttag acatataaaa
    42721 tcactcctta aaaattatat tctctatact ctttaatttt cgtttttatc aatattatca
    42781 cttagttgca tattcccttt ctatcaaaat gtatatacaa aattaattta gataaagatt
    42841 gtataaataa aatagctaag agaattacac ctatatccaa atttgatata tccaaacctc
    42901 ttgtataatt tgctgaaaag aaaacagcta ttagcaaaat agaatataac attatttttg
    42961 atgcaatatg atcaaccttt aataacataa gttttgacgc ctcgtcaact aaatcattat
    43021 attttttatt atacatgaag tcacatgccc aaaaagcgaa taaaattata aaagtaatac
    43081 aaagatttcc ctctttaaaa ataaactttt ttaataatga gtctataaaa aaataggata
    43141 tcataagtaa ctctgaaaca agatttgttt taacaccaag ctctgattta gacatataaa
    43201 atcacccctt aaaagttata tatttataac accttatgtt ataaatatat aacttttcca
    43261 aataaattgc aatagaatat tgaaaatatt caataatatc ttcataaata tattttataa
    43321 aagattttat aataaacatt acaatacagt actaaattag tttatttcat ctatcatctc
    43381 aatcatatca tttactaact attattctaa tgagcatata acattgaaac ttataattat
    43441 acaacctaaa tgcctcccaa tgtaccctca aaacatcatt tcctgtaact gaagtataat
    43501 tggtatattt tatcactgaa ataaaaaaac actagtcaat aaagactagt attttcaagt
    43561 attttatcat tcttttttta attattggag acgaatcatc agaataatgc ccataattta
    43621 tctatatgca aattctaaat ttaaaataaa gtttcagata aatttactat tctatgctat
    43681 gatacaacag aaaaaactga aatctatgag tggtagcttc atataatcct agttcctaca
    43741 gtaatcaaaa ctgaggttta ttctatatgt aactaatgat aaattttatt ataggagtta
    43801 ttagatctat ttgtgttact ataagtagta attatatata tgataatttt ttaacacttt
    43861 tctgttggct atatagaaag tggtttagaa tttaaattta aataaaattt aaattcacca
    43921 aaaagaaatc tatattagaa accactactc tattccacca gattgtaatt ttttgttctt
    43981 tatatcacaa tgctatacca tattaaattg aaaaataagt tttaaattta tttgttacaa
    44041 ttcattaatt caaaaaaata ttttgagtca tgagttttgt aaagatttag ccatgaattt
    44101 aatgcttctg attcaaaaac atctaaaagt ttcaatactt gaaacgtaaa ttccaacgga
    44161 gcaattcctg aagccgtaac taaattttca tcactaacta cagattccgt tttataatat
    44221 ttttctccag agtaatttgg tattaccatt ttaagaaact ctaagtcatt acttgtatga
    44281 tttctaaaat ctaatagccc ttttttagct aggcctaatg tagctccaca tatggctgca
    44341 actatagaat cttgtcttaa agcttcttta actttttcta atattatctc atgattcata
    44401 gataaccaag tatttccccc tggcaaaatt aataaatcct tactttccat attaaactca
    44461 tcaactgtaa tttcaggtaa aacttttaac ccacccattg ttataatagg atttttatca
    44521 attcctacag taattacttt tagtggcttt aatccttttt taaaatatct tcctgtattt
    44581 aattcagcag ttaaatatgc cacttcccaa tctgacatag tatcaaatac atacatatat
    44641 acttttctat ttttcatctt ttttactcct tatgtaatta atttatatat ctaattataa
    44701 aataacttaa ctgacatatt cagtcagtta agctattaaa tttgataata atcaattaat
    44761 tctagtaaat cttcaattat tttcttccta aggcttagtg gttcaattac ttgtattgtc
    44821 tttctataag gtaaaagtat atttggtatg tacttgcata ttacttcctc ttcaagcata
    44881 aatattattt tattaggtgt tctttctttc aagtagtgcc ctaaaaacca atgttggctt
    44941 aaactatcta aagaatctat actcccttct ataactaatt gaattatatt ttgttcatct
    45001 tttatttcag gtataattcc ttttataaaa aattcacttg ctgaaaattc tgtcggtctg
    45061 ttaaatgtat ttgatgtttc tatgatttca ctaatcctat ccactctgaa actacgaacc
    45121 tcatttctca tattacaaaa tgcaactacg taccaattat tattccagtg aacaattcca
    45181 tatggattta taattctata ttttgatttt actttacgac ctgcatgata gttgatttct
    45241 acagatagct cctttaatat actattctcc aattttttaa gtactgattc tatagacact
    45301 ttcccaattg gttttattac ttcaagggct cttaagtggt ttgttaaaat atcttcttgt
    45361 ttttgatttg aatacatttt taactttaat atcgatttat ctaatgcttc gtctaagaag
    45421 tatccttctt ttttagcaaa tagtgctgca tgaagtagag atttttgctc ttctatatca
    45481 aaaaaaagag gtgctttagt aaaattattt aaaaggctat acccaccatt atgacctgta
    45541 tctgaaatta taggtactcc actcgcagaa agtacatcaa tatatcggta cactgttctt
    45601 atatttattt ctaatttttc agctatctgt tttgctgtaa tttttttgtc agagtttaac
    45661 atccacagta tagacatcat attgtcaatt ttagccatgt agtttcacct ctttctattt
    45721 gttatataaa gttattatat aactttttga ttgatttttt acaaaaaaac attagtaaac
    45781 tgctaataat ttatactaag atttatttca aatatttata gatagtcttt ttctatagtt
    45841 aagttatcca ttaaattaca tagtagtata tctattttag ttgatatatt ttcagctacc
    45901 tcccttgaat attattacaa taagtctaaa tcttctttct tccataaata tattatgagg
    45961 aaagactatc atctttaatg gtttaatagt ataaaagata ttaatttaaa aaaatctatt
    46021 tttatatcag atgggtattg ttttttataa aactgaaaaa atcacctaat agaatctatg
    46081 attttttaac ataacctcca taaattagtt ccaattatca cttcaaattc aaatttttat
    46141 ctgaagaata tacaatcata tttccatact caacataata ttgagtgttt ggcttgtatt
    46201 tacaaattat tattctaaca aaaacaacta tacatagatt aaaatcatct tctaaacata
    46261 actactaaaa ttgaattaat gatatcaatt ccattaatct cttttaataa aaaattctct
    46321 tttctatatg aaaattattt caaaactttt aagttaaata caaaaatgac tataaataga
    46381 tttttattta cacaaatcta tttatagtca ctatagttta tccaataaaa taataaaata
    46441 aatatgtaca caataaatgt tatttacgtc ttaagtattt atttgttaga tttttaatta
    46501 aaaaaaacaa gctaatgaac attaatgcta aatctagcat tatattgctt tgatctcctg
    46561 tttgtacatt ttgacctaca ttactatcta aactttcatc tgtatctata tttatatctg
    46621 gttttccatt cccatctgta tctatattta tatccggttt tccatctcca tctatatcta
    46681 tatttatatc tggttttcca tctccatctg tatctatatt tatatctggt tttccatctc
    46741 catctgtgtc tatatttata tctggttttc catctccatc tgtgtctata tttatattcg
    46801 gttttccatc cccatctgta tctatatctg gtttgctatt tcctccatta tctgggtctg
    46861 gtttactatt tccaccgtta tctggatccg gtttgctatt tcctccatta tctggatctg
    46921 gtttaccatt gccaccgtta tctggatctg gtttgctatt tcctccgtta tctggatccg
    46981 gtttgctatt tcctccatta cctgaatccg gtttgctatt tcctccatta cctgaatctg
    47041 gtttgctatt tcctccatta cctgaatctg gtttgctatt tcctccatta tctggatctg
    47101 gcttatttag atttggatta cctgtatcat aacctcctga gccagtatct acatttttat
    47161 caggcttcca ataatcatct actccatcat tatctgtatc tattgctgga cgattataat
    47221 ctgtatcagg gtttccatct ccattggtat ctatattttt atcaggtttc caaataccat
    47281 ctccatttcc accttctgta ctaggcttcc attcacctgt attatcagta tctatgttaa
    47341 tatctggctt ccaatcacca ctcgtatcta tattgatatc tggccttcca tcaccatcag
    47401 tgtctatatt tatatccggt attccatccc catctacatc tacatttgtc atatctaact
    47461 ttaacttctt ttcatcctca ctaccttcaa tgtaatttat atcatctcca atatatttta
    47521 cagtaatagt ttgttcagta gtaaaaatat gatgattgct atctaaaggt ctccattcaa
    47581 tagatgcagt actataatta tgactctcac tacccttatt atgagttttt aattctactg
    47641 gatctttata ttcctttcca ttaatataga attgtacgta acctcttgga gaggcacaat
    47701 ctggtccttc tttcttatct ggtgaaatag taacatttaa tgtaaacgta tctgttggtt
    47761 taaaaacatc agttttagct ttagactctt ctacaactaa tgaagtttct gtatcagcag
    47821 gaataatttc tgccttataa tatgctctat gcccccaata agcatcctta aaaggatata
    47881 tactcgaaaa ctgtgttgat gtaatgctta attgatattt cccagcatca acttgttttg
    47941 taagatcatc acttcctaaa tttatatctg gttccatcgt ttcctcattt aaacgttgag
    48001 aactaatagt cataaatttt ttatctgtga gtttttcacc tttaggagta attattggaa
    48061 taccaccatc tttaaatatc caatctaaaa atgatttttc tacgtcttct tcaaatggta
    48121 atccatcata tcttttaata atcaaatatg gtggagtatc atcaatagta aattcttcat
    48181 attgctttaa aaattgagaa cctgaaccta tatctttaat ataaaaatca tctggtttta
    48241 gaacttctcc agtaatttta tctataacaa ctaaattaac agatacttca gatcccttaa
    48301 attgatcaga gaaccataag taaagaatcc cttgagcatc tgtataacta ggtgctccat
    48361 aaggataaat ttttccatca attagcattt taaaatcatc aactagtgta gtactaactt
    48421 tatcttgccc taaatacgtt agagatattt tattcataaa aacttttgtt ttcttttcta
    48481 aatcaccgta tgcaactgct ccacctaaac ttttgaatgt tgttgctttt aatgaaccac
    48541 ctgttactat aacatctccc gttgtagcac ttaggtcaaa aatccaatct cccactcctg
    48601 tcatataagg taaaatcgtt cctccagtta caagtatacg atatcctcta tttgttcctg
    48661 gattaacaca tccatcccca aatgcactac catgtgcacc tccatatgaa taggaaagtc
    48721 caccattaat tgtaatattc ccactataac cagaacctgt gctaggatct actactgagg
    48781 gacttaatgc attctttgtt gttgtatagt atcctccacc tattccagct ccatggtatg
    48841 cacctttagc agttataata cctccattga ttgtgatatc tccaccacta ccattaccgc
    48901 ctccacctat tccagctcca tatcctgtat tacgactcga ttcttgacct atagcagtta
    48961 tagcaccacc attaataata atatttcctc cactttcagt atttccacca ccaatacctg
    49021 cagaataata atttccaaca acttttaaac ttcctctatt attactatct agtagtgtaa
    49081 ggcgatctcc tttttttaac ttgtctccat tttctagagt tacatctcta ggaatttttc
    49141 caccctcagg aactataaac tctccttcaa tatctctatt tacaacagaa tcatcaataa
    49201 ttagagtagt accttttcct gctctcatac ctggataata tacatcacct gactctagct
    49261 tgttttcact accatcttgt aatataacat gtgcatatgc accaccatct ttatctggtg
    49321 ttaaagtaaa tgggctatta gatgcagttt taatatttac tccatcaaat attaattcag
    49381 cttttacatc tttaggtata acaatcctat gtgttgttgg agtatttgga ttgttatttt
    49441 gaattgtcat ttgttttcca ctaagaatag ttaaaacgcc acttgcaaat ttaaaatcga
    49501 catttatttc tccaccacta attttaaagt ctcctacaga cgtaggctct tctgcagtgg
    49561 cttcttcttc tacaactact gcattagcat ctccttctgc atctcctgca ttagtatctc
    49621 cttctgcatc tcctgcatta gtatctcctt c
//
LOCUS       DAYAKB010000024        49024 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.024, whole genome shotgun sequence.
ACCESSION   DAYAKB010000024 DAYAKB010000000
VERSION     DAYAKB010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.024"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            170..550
                     /gene="acpS"
                     /locus_tag="ACGI3L_001647"
     CDS             170..550
                     /gene="acpS"
                     /locus_tag="ACGI3L_001647"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFG9197359.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            565..1026
                     /locus_tag="ACGI3L_001648"
     CDS             565..1026
                     /locus_tag="ACGI3L_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFG9197360.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            1047..1637
                     /gene="gerS"
                     /locus_tag="ACGI3L_001649"
     CDS             1047..1637
                     /gene="gerS"
                     /locus_tag="ACGI3L_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="germination lipoprotein GerS"
                     /protein_id="HFG9197361.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQDDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            1652..2809
                     /gene="alr"
                     /locus_tag="ACGI3L_001650"
     CDS             1652..2809
                     /gene="alr"
                     /locus_tag="ACGI3L_001650"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFG9197362.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEKSVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            2842..3129
                     /locus_tag="ACGI3L_001651"
     CDS             2842..3129
                     /locus_tag="ACGI3L_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HFG9197363.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            3098..3481
                     /locus_tag="ACGI3L_001652"
     CDS             3098..3481
                     /locus_tag="ACGI3L_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFG9197364.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            3652..4479
                     /locus_tag="ACGI3L_001653"
     CDS             3652..4479
                     /locus_tag="ACGI3L_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFG9197365.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            4472..5413
                     /locus_tag="ACGI3L_001654"
     CDS             4472..5413
                     /locus_tag="ACGI3L_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HFG9197366.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEVIIAKRM"
     gene            5836..6930
                     /locus_tag="ACGI3L_001655"
     CDS             5836..6930
                     /locus_tag="ACGI3L_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197367.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            7156..7572
                     /locus_tag="ACGI3L_001656"
     CDS             7156..7572
                     /locus_tag="ACGI3L_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197368.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(7754..8323)
                     /locus_tag="ACGI3L_001657"
     CDS             complement(7754..8323)
                     /locus_tag="ACGI3L_001657"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFG9197369.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            8477..9634
                     /locus_tag="ACGI3L_001658"
     CDS             8477..9634
                     /locus_tag="ACGI3L_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HFG9197370.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            10238..10708
                     /locus_tag="ACGI3L_001659"
     CDS             10238..10708
                     /locus_tag="ACGI3L_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFG9197371.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIY"
     gene            complement(11417..12571)
                     /gene="nagA"
                     /locus_tag="ACGI3L_001660"
     CDS             complement(11417..12571)
                     /gene="nagA"
                     /locus_tag="ACGI3L_001660"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFG9197372.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(12654..13379)
                     /locus_tag="ACGI3L_001661"
     CDS             complement(12654..13379)
                     /locus_tag="ACGI3L_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9197373.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            13648..14577
                     /gene="pfkB"
                     /locus_tag="ACGI3L_001662"
     CDS             13648..14577
                     /gene="pfkB"
                     /locus_tag="ACGI3L_001662"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFG9197374.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(14706..15623)
                     /locus_tag="ACGI3L_001663"
     CDS             complement(14706..15623)
                     /locus_tag="ACGI3L_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFG9197375.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            16100..17263
                     /locus_tag="ACGI3L_001664"
     CDS             16100..17263
                     /locus_tag="ACGI3L_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9197376.1"
                     /translation="MFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKLSR
                     FIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNPYD
                     YLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKNDEN
                     NYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVIDRK
                     DEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPKSF
                     IDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFKEK
                     YNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            17312..18163
                     /locus_tag="ACGI3L_001665"
     CDS             17312..18163
                     /locus_tag="ACGI3L_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HFG9197377.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            18489..20390
                     /locus_tag="ACGI3L_001666"
     CDS             18489..20390
                     /locus_tag="ACGI3L_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9197378.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            20393..21436
                     /gene="ypdE"
                     /locus_tag="ACGI3L_001667"
     CDS             20393..21436
                     /gene="ypdE"
                     /locus_tag="ACGI3L_001667"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFG9197379.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNKKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            21451..21756
                     /locus_tag="ACGI3L_001668"
     CDS             21451..21756
                     /locus_tag="ACGI3L_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9197380.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            21853..22188
                     /locus_tag="ACGI3L_001669"
     CDS             21853..22188
                     /locus_tag="ACGI3L_001669"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9197381.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            22220..23542
                     /locus_tag="ACGI3L_001670"
     CDS             22220..23542
                     /locus_tag="ACGI3L_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9197382.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILSNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEGLLDDLGLDF"
     gene            23564..24622
                     /locus_tag="ACGI3L_001671"
     CDS             23564..24622
                     /locus_tag="ACGI3L_001671"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFG9197383.1"
                     /translation="MERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVTKDKN
                     YQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSIQEYL
                     SLKNEGFEINLITNELWKLRAIKSKEEIKLIKKACEITDEVFDEVISEIKKDMTELEV
                     SALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVYQGYQ
                     SDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKHGFGE
                     YFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDIVIID
                     GKGVPLNKTSKEFIILGE"
     gene            24627..25814
                     /locus_tag="ACGI3L_001672"
     CDS             24627..25814
                     /locus_tag="ACGI3L_001672"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9197384.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(26011..26883)
                     /locus_tag="ACGI3L_001673"
     CDS             complement(26011..26883)
                     /locus_tag="ACGI3L_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFG9197385.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(27277..27468)
                     /locus_tag="ACGI3L_001674"
     CDS             complement(27277..27468)
                     /locus_tag="ACGI3L_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197386.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            27688..28734
                     /gene="cobT"
                     /locus_tag="ACGI3L_001675"
     CDS             27688..28734
                     /gene="cobT"
                     /locus_tag="ACGI3L_001675"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HFG9197387.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            28766..29326
                     /gene="cobU"
                     /locus_tag="ACGI3L_001676"
     CDS             28766..29326
                     /gene="cobU"
                     /locus_tag="ACGI3L_001676"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HFG9197388.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            29336..30109
                     /gene="cobS"
                     /locus_tag="ACGI3L_001677"
     CDS             29336..30109
                     /gene="cobS"
                     /locus_tag="ACGI3L_001677"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HFG9197389.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            30129..30743
                     /locus_tag="ACGI3L_001678"
     CDS             30129..30743
                     /locus_tag="ACGI3L_001678"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFG9197390.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENNSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      30810..30989
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            31104..32618
                     /locus_tag="ACGI3L_001679"
     CDS             31104..32618
                     /locus_tag="ACGI3L_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HFG9197391.1"
                     /translation="MGKKIMLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMAL
                     NSFITKEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSS
                     KYHDYKLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPV
                     IIVGDIDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKV
                     PVIGVVPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVS
                     IRYVDYGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQ
                     MLGKKLKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGK
                     KVKGYEIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEIS
                     FTRAILNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            32657..34033
                     /locus_tag="ACGI3L_001680"
     CDS             32657..34033
                     /locus_tag="ACGI3L_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HFG9197392.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            34034..35005
                     /gene="cbiB"
                     /locus_tag="ACGI3L_001681"
     CDS             34034..35005
                     /gene="cbiB"
                     /locus_tag="ACGI3L_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HFG9197393.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            35037..36107
                     /locus_tag="ACGI3L_001682"
     CDS             35037..36107
                     /locus_tag="ACGI3L_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9197394.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            36109..36996
                     /locus_tag="ACGI3L_001683"
     CDS             36109..36996
                     /locus_tag="ACGI3L_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HFG9197395.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            36984..37616
                     /locus_tag="ACGI3L_001684"
     CDS             36984..37616
                     /locus_tag="ACGI3L_001684"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HFG9197396.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            37625..38851
                     /gene="cbiD"
                     /locus_tag="ACGI3L_001685"
     CDS             37625..38851
                     /gene="cbiD"
                     /locus_tag="ACGI3L_001685"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase
                     CbiD"
                     /protein_id="HFG9197397.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDNLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            38848..39456
                     /locus_tag="ACGI3L_001686"
     CDS             38848..39456
                     /locus_tag="ACGI3L_001686"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HFG9197398.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            39446..40021
                     /locus_tag="ACGI3L_001687"
     CDS             39446..40021
                     /locus_tag="ACGI3L_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HFG9197399.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            40014..40766
                     /locus_tag="ACGI3L_001688"
     CDS             40014..40766
                     /locus_tag="ACGI3L_001688"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HFG9197400.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            40750..41871
                     /gene="cbiG"
                     /locus_tag="ACGI3L_001689"
     CDS             40750..41871
                     /gene="cbiG"
                     /locus_tag="ACGI3L_001689"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HFG9197401.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            41868..42593
                     /gene="cobJ"
                     /locus_tag="ACGI3L_001690"
     CDS             41868..42593
                     /gene="cobJ"
                     /locus_tag="ACGI3L_001690"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HFG9197402.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            42590..43342
                     /gene="cobK"
                     /locus_tag="ACGI3L_001691"
     CDS             42590..43342
                     /gene="cobK"
                     /locus_tag="ACGI3L_001691"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HFG9197403.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            43361..44839
                     /locus_tag="ACGI3L_001692"
     CDS             43361..44839
                     /locus_tag="ACGI3L_001692"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HFG9197404.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            44869..45774
                     /gene="hemC"
                     /locus_tag="ACGI3L_001693"
     CDS             44869..45774
                     /gene="hemC"
                     /locus_tag="ACGI3L_001693"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HFG9197405.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            45764..47263
                     /gene="cobA"
                     /locus_tag="ACGI3L_001694"
     CDS             45764..47263
                     /gene="cobA"
                     /locus_tag="ACGI3L_001694"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HFG9197406.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            47280..48245
                     /gene="hemB"
                     /locus_tag="ACGI3L_001695"
     CDS             47280..48245
                     /gene="hemB"
                     /locus_tag="ACGI3L_001695"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HFG9197407.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            48398..48976
                     /locus_tag="ACGI3L_001696"
     CDS             48398..48976
                     /locus_tag="ACGI3L_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HFG9197408.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        19471 a         5158 c         8713 g        15682 t
ORIGIN      
        1 ttgtatataa tattcattac aaataatttt aaaagttaca gttttattat aatgattatt
       61 aaattaagat aagtaacata aactaaataa taatgtgtat tatcgatagt aaatttataa
      121 attcattatt aattattgaa agaagtatta taaattttct ggaggaacaa tgaatatatt
      181 tgatattggc gtagatataa ttgaaattga tagaataaga aaggctgtag acaaaaataa
      241 taggtttttg gagaagatat ttacagatag agaaatagag tattttaatt ctaagaattt
      301 taaagcagaa agtatagcag gtaatttcgc agccaaggaa gctataagta aatctatagg
      361 tacaggaatt agattgttta attttaaaga tatagaagtt ctcagaaatg aaatgggaaa
      421 accaatagta aaaacttata ataatctagc aaaaatgtgc atagattata atgttttaga
      481 aataaaagtt tcaatatcac attcaaaaga ttatgctata gcaaatgcga taaccataat
      541 taaggactaa ggagtgatta cattatgatg gataaaacag caaaagaaat aatgacaaca
      601 gatgtaatag tagcaaaaca agatgatagt atagcagatg tagctaatat gctaattgca
      661 gaaaaaatag gaggtctgcc agttgtagat tcagagaata gagttgttgg aataatttct
      721 gaaacagata ttcttaaaaa agaaaaatat atagaagcac ctctctatat aaatctatta
      781 caaggattga ttttcttaga tgacttaaaa aaagttgaaa aagatataaa acaagtagct
      841 gcttataagg ttggagaact tatgtctaaa gatataataa aggttcatga agatgataag
      901 tttgatgatg tagctaatgt aatgattaaa aaatcaataa acagagttcc tgtagtagat
      961 gatgacaaca aacttaaagg tataatttgt agatatgata taataaaagc tttatacaat
     1021 gaataaactg aagtaggagg tgtgatgtga gaaaaaagtg gaccatagta tgtattatgt
     1081 tcttggcact ggttataatt gtaataggat gccaaaaacg acagtccaca aaagaagaag
     1141 tatacaaaga ttttcaaaag cagatttctg atatgaatta ttacagttgt aaagctgaag
     1201 tagaagtagt tggaaataaa agcccacaca attatgtttt aattcatact tataaaaaaa
     1261 ccgataacta taaattagaa gtaatttccc caaaacattt aaaagggaaa agtatagaat
     1321 atcaagatga taaaatatta gttaaaaatc caaagattag tgatgtagtg gagttaccta
     1381 atacaggaaa aaataatcaa tatctttttg taggagactt tataaaaaac tatcttcaaa
     1441 atgaggagat gaaagtaaag ttatccaaag gacatttggt tttagagact tttattcctg
     1501 gggataataa atattttaac aagcaagtat tatatgtaaa tgctgacaca aaaaatcctg
     1561 aaaaaatgga agtgttagat aaagagggag tgccaagatt tacagtaaaa tacaaagatt
     1621 ttgaatacag aaactaaggg ggactaaaga catgcaaaaa ataacagtgc ctacatgggc
     1681 agagataaat ctagataact taagatttaa cttaaataat attaaaaatt tattagaaga
     1741 agatattaag atttgtggag taataaaagc tgatgcatat ggacatggtg cagtagaagt
     1801 tgcaaaattg ctagaaaaag aaaaagtaga ttacttagca gtagcaagaa ctgctgaagg
     1861 aattgaactt agacaaaatg gcataacact tcctattttg aacttgggat atactccaga
     1921 cgaagctttt gaagattcta taaaaaataa aataactatg acagtttatt ctttagaaac
     1981 agcacaaaag ataaatgaaa ttgcaaaatc tttaggagaa aaagcctgtg ttcatgttaa
     2041 aatagactca gggatgacta gaataggttt ccaacctaat gagaagtcag tacaggaaat
     2101 aatagaatta aataaattag aatatataga tttagaaggt atgtttactc attttgctac
     2161 agctgatgaa gtaagtaaag agtacactta taaacaagct aataattata aatttatgtc
     2221 tgataaatta gatgaggctg gtgtaaaaat agctataaaa catgtatcaa acagtgcagc
     2281 tattatggat tgccctgatt taagattaaa tatggtaaga gcaggaataa tattatatgg
     2341 tcattatcca tctgatgatg tatttaaaga tagattagaa ttaagaccag ccatgaaatt
     2401 aaaatcaaaa atcggacata taaaacaagt tgaaccaggt gtaggaataa gttatggact
     2461 aaaatacaca actacaggta aagaaacaat agctacagtt ccaataggat acgcagatgg
     2521 atttactaga atccaaaaaa atccaaaggt tcttattaag ggagaagtgt ttgatgtagt
     2581 tggtagaata tgtatggatc aaataatggt tagaattgac aaagatatag acataaaagt
     2641 tggagatgag gttatactat ttggagaagg cgaagttaca gctgagcgta tagctaaaga
     2701 cttaggaact ataaactatg aagtgttatg tatgatatca agaagagttg accgtgttta
     2761 tatggaaaat aatgagcttg tacaaataaa cagttatttg ctaaaataaa accatgatat
     2821 tataatctgg gaggcgattt tgtgtacgat aagagtaaag aaaaaataga agttacttta
     2881 cctgactctc tgatttctga agttgatagt atagttcaga tggagaacag taacagagaa
     2941 gattttgcaa aagctgcttt tcagttctat ataactcaga aaaagaaaat tcatattaaa
     3001 gaatctatga aaacgggtta tagagaaatg ggtcaaatta atctgtcact agctgaatta
     3061 ggtatgacag ttgaagaagt atcttctgat gataaaaatg aagggaagat tgcccaaggt
     3121 gagtactaat tgtgaaataa agcgtggtga tttatattac gctgatttaa gtccagttgt
     3181 tggttcagag cagggaggcg ttagacctgt tctgataata caaaatgatg taggtaataa
     3241 atatagtcct acagttatag tatcagctat aacatctcag attaataaag ccaaattacc
     3301 tactcatgta gagataagtt ccaatgaata tgggcttaat aaagactcag taattctttt
     3361 agagcaaatt agaactatcg ataaaaagag actgagggaa aaaattggtt gtctagatga
     3421 aaatatgatg ataaaagtag atgatggact tcaaataagt ttaggattgt ttacttttta
     3481 aagagggatt tgtcttttat tagacaatcc cttttttctt ttaaatatct cttaaggttt
     3541 aattttaatg tactatgtta ataaaattaa aaataacgca aaaaaatagc ataaaagtga
     3601 tataataata tggaattgat ataaaattac gaactcaagg gaggtaattg catgagagac
     3661 cataaaggat taaatgagat tgcgcgtatc ataagaagag atatagtttc aatgatacat
     3721 agagccaaat ctggacatcc aggagggtca ttatcagtag ttgaaatact tactgcgtta
     3781 tactttgatg aaatgaatgt ggattcttca aatcctaaaa tggaggatag agatagattt
     3841 gtattatcaa aaggacatgc tgcaccagca ttatatgcta cattggctga aaaaggctat
     3901 tttgataagg aagaactgaa tggattaagg aagataggaa ggatgttaca aggtcatcca
     3961 gacatgaaag gcacgccagg tgtggaaata tctactggtt ctttaggtca aggtttttca
     4021 gttgcatgtg gtatggctat ggcatcaaag ttggataatg ctccgtggaa tgtgtatact
     4081 ttgcttggtg atggtgaggt tcaagaagga attgtttggg aagctgctat gagtgctgca
     4141 cattataaac ttgataattt aattgctttt ttagataata atggacttca aatagatgga
     4201 gatatagaaa gcgtaatgag tttaggttca atagttgata aatttaaagc ttttggttgg
     4261 aatgtaattg agatagatgg acatgatttt gaccaaatat ttgcggctct tgatatagct
     4321 aaatcaacag ttaaaaaacc tacaatgata gttgcaaaaa ctataaaagg caaaggaata
     4381 tcttttatgg aaaatcaagc aggatggcat gggacagctc caagtgatga ggagctagaa
     4441 aaagctttgc ttgaattagg aggtgctgac aatgagtaaa atggcgacga gagaagcata
     4501 tggtaaagca ttagtaaaat taggtcaaat aaatgacaat gttgtagtat tagatgcaga
     4561 tttatcaaag tctacaaaaa cacatgattt ttacaagtca tttccagata gattttttaa
     4621 tatgggtata gctgaacaaa atttaatagg cgctgcttgt ggattatcaa ctgctggtaa
     4681 aatacctttt gcaagtactt ttgctatgtt tgctacggga agggcttttg agattataag
     4741 aaattcagtt tgttatccaa agctaaatgt aaaaatatgt gctactcatg caggtcttac
     4801 tgttggagag gatggagcat ctcatgaaag tgtggaagat attgctataa tgagagctat
     4861 accaaatatg acagttcttg ttccagctga tggagttgaa acagaaaaaa ttatttttga
     4921 aatagctaag tataatggac ctgtttatgt tagattaggg agaagttcag taccagtttt
     4981 atttgatgaa gattataaat ttgaaatagg aaaaggtaca gtcttaagag aaggaaagga
     5041 tgtatcaatt atagcttgtg gaattatggt aaatgaagct ctattagcac aagaaaagtt
     5101 gcaagaagaa ggtataagtg ctagagttat aaacatgtcc tcgataaaac ctatagacaa
     5161 agatttaata ttagaatcag caaaagaaac gaatgctatt gtaactgtag aagaacatag
     5221 cataattggg ggattaggtt ctgctgtaag tgaggtagta ggagagtctt gtccaaccat
     5281 tgtaaagaaa gttggaatta aagatacatt tggagaatct ggtactccaa atgaattgtt
     5341 aaaaaaatat gaattaactt gtgatgacat aataaagact gttaaagaag ttattattgc
     5401 aaaaagaatg taagagatat aaattattca tgtttgttaa taatataata tatttaaaag
     5461 agaggtataa agtgttatat taatttatat ctctcttttt tttatatgat atcaatatat
     5521 caaaaatgta ataaaatatt caaattttta caaaaataga gaaaatattc aaatatatat
     5581 tgactattca gaaaaatatg actaatatat aatttataga gaaactaatt ttatatataa
     5641 tgactactta gataaaagaa tctaaaaaaa ttatgagagg aggagtaggg tataaaatca
     5701 gattataagt tttaagttat tatactaaaa agctataaaa cagttatcat gtattttatg
     5761 ttaaaggaaa ttgtaggtag tttatcgaat tgtttaatca gaagaaaaaa tttcacatgg
     5821 ggaggtaact gagatatgtc agaaaaagta aatgttaaaa cagtcatcag tttcgcaggt
     5881 gcgtatgtag caacagtaat cggttctgga tttgcaacag gacaggaaat aatgcaattc
     5941 ttctcttttt atggttttgc aggtattatt ggtgggataa tttcaatggt attattctca
     6001 tggatgggtg cttcagttat gtcaaaaggt aaagagcttc aacttaaaga acctatcaaa
     6061 atttatcgtg tttattgtgg taagtattta ggaatattct ttgaatggtt tggaccttta
     6121 ttcttatttg gtgttttcgt agtaatgatt tcaggagcag gagcaacttt aactgaatac
     6181 tatggattaa atccatttgt aggtagagta ggtatggcag tagtagcatt attaactgtt
     6241 tcactaggtc ttgataaatt atcaaagata ctaggtggaa tagggcctat aataataatc
     6301 tttacacttt tagttggtgg tataagttta gctaaaaaca taggtaatat aggagaagct
     6361 gcacaagttc ttagcactgt aaagatagct aaaccagttc caaatgccta tctatctggt
     6421 gtaatatata ctacttataa cacaattgtt gttatggcat tcttaactgg attaggagca
     6481 agtgctgcta acaaaaaaga agctatttgt ggtggtatat taggtggagt agcacttatg
     6541 gctgcagcta taatgatgca cttagctatt ctttctgata taggaaactt atattcaaaa
     6601 gcaataccat cattattctt agcagataag atttcaccag taattggagt tttattctca
     6661 ataattctta tattaggtat atatacaaca gctgtacctt tattatggtc agtaactaat
     6721 agatttgtag atgataaaca tcctaagttt aaattaataa ctttaatagc agctatatta
     6781 ggtcttatag gtggcttcct accatttgat aagctggttg gtattttata tccatatact
     6841 ggatatatgg gcgtcataat actggtttgt gttctttata gacagattac aaaaacatct
     6901 ggatatcaag aaggaatcag tgacaaataa gtatttttta atattgtaaa ctcaagagct
     6961 atatgaaaac aatgaaaatg ttttcatata gctcttttta ttttttagct cgtttattat
     7021 gaaatagaaa aaacatgttt tttagttaca ttacatatat ttataattat gtataaatat
     7081 atactaatca ataatttaga gtctaagata agtttataaa tcatatattt agaatatatg
     7141 ggaggagtga taagattgaa tgtaaagttt aatattaaag gtataattta tggagttata
     7201 gctcttgtat tcgttatagg gggatttata ttcataccaa gtatgtttgt agagaaatct
     7261 aaacccatag attatacagt attacaaaga aattcaatac cagaaaagat attagatgtg
     7321 atggataagt atacaaatga agaaagagca ttagcggcta aaatcgataa caaaatatac
     7381 attatagtga ctagaggaaa taataaatat ggtatagaaa tggacaaaat agaaagtgtg
     7441 gttgaggaag gaaaggatgt tttgagagtc aagataaagt ataaagataa ggaagattct
     7501 tttccataca tagttgttga aacaaatatg agtgaacttc cagatagaat agaattaaat
     7561 gcgacgaaat aagaaggtat tttataatta aataactgca tattgtacaa taaagtcatg
     7621 gtttttatta atgtaagtaa attgtatatg gttcttattg ttgtaaaagc catgacttaa
     7681 aatgcttata aagtaagata ttaacagtag tatttattac tatattaaat ggggtctgga
     7741 aatacttaat attctaatta tttggagtga taattctagt ttcagtaact atgtagtcta
     7801 attgtgcatc atgagtttct tttggaatag aatcgaatat ctggaagtca aatgctatgc
     7861 cgatagttat agcatctttt cttaagtttt ctaaaaatct atcataaaat cctccaccat
     7921 atcctaatct atagcaatgt atatcatatg ctacagctgg tacaattaca acatctaagg
     7981 ccttaatatc aattgtaggt gatttttcgt taggttctct tattccatat gctccaattc
     8041 tcaatccctc ttttaaatct gttatttgag tagggattaa tgtatgattt tcttttattg
     8101 tgatgggact tgatactatt ttctttagag acaaaagttt tttgattaaa ttatctgttt
     8161 gaacttcatt gttaaaattt agataaagca ttatattagt tgcatttctt atatcttcca
     8221 tttgaagtaa tttttcagtg attaaatttg aattactaag tacgaagttt gcactcttat
     8281 tttttcttga ttcaataact ttttttctaa attctttttt cataaaataa ttcctccctt
     8341 aatatgttat aatgtgtaca gcaattgtat ttaatataaa ttttagtata atttattgta
     8401 ataaagcaat atatttgggt aaatgtaata aaaataacag ctagtcatat aataataata
     8461 gtttatgtaa aaggagatgt atcttgtgat ttcaaagaag aaagctattt ttttaggggt
     8521 gattttagta attataacag ctatggttac atcagcattt cagttgacat tggggaataa
     8581 agttgtaata tcgaaagaac tctatgaaga ctataaaaaa tatgataagt tgttaggact
     8641 agaatctatt ataaaacaag atttttataa aaaagtatca gatactgatt tggtaaatgg
     8701 agcagcaaaa ggtctatttc taggaacaaa tgataagtat tctggttatt atactaaaga
     8761 tgaaatggag aatctaatta atgatagtga aggttcttat gttggtgtag gtatgtatat
     8821 aggggcatca aaagatggtg gcttagtagt agttcccatg aaagattctc cagcagagaa
     8881 agcaggtgta aaatcagggg ataaattagt aaaagtcaat ggaaaatctg tctcatataa
     8941 aaattcagat gaagctgttc gtatgatgaa gggtaaaaaa ggtaaaacag ttgaactgac
     9001 tatattaaga gaagataaac aattgaactt taaagtaaaa acagaccaga taattgagaa
     9061 gagtatagaa agtaaagtaa ttgataatga tttaggatat atagaaatta cccaatttat
     9121 atcaagtaca tatactgact ttgataaagc tttaaaagaa ttaaaagcaa aaaatatcaa
     9181 gggattagta atagacctta gaaataatcc tggtggaatg ctagatatat gtaaagaagt
     9241 tgctgatgag ttaattggtg aaggaactat agtatataca aaagataata agggaaatac
     9301 tgagtacttg aaatctgata aagaaaaatt gggacttcca atagtagtgt taactaatgg
     9361 agaaagtgct tctgctgctg aaatattaac agctgcaatc gttgataata aagaaggtat
     9421 ttctgtaggg actacaactt ttggtaaagg gttggtacaa tcagttgtaa gattgaagga
     9481 tggaacagga tacaagttaa ctactgctca atattttaca cctaatggag attatatcaa
     9541 tgaaaaaggt ataaagccta ctattgaaga aaaagatgaa aataaacagt tagatgtagc
     9601 aactaagtgg cttagagaac agattgataa ataggattta atttttataa acttatacta
     9661 taaaataaag aacattataa aagagatgtc tcaaaatgaa ctttttagtt catgagggag
     9721 tctggaaata tttatgtgta ttctttaaat aaaaatttat tttttaagtg ataattaaat
     9781 ttttacagac agggctatgg ttttaaaaat catagcctta ttttgatatt ttttaaaaac
     9841 acattgcaac ccagttgttc caaatattat atcatttact tttaaaatat cgtaaactgc
     9901 atactatata ttcattataa tataatttat ctaactagaa cctcagttta ctaattaaat
     9961 tagatgcata gaataacttt tttaaacatt gaaaataaat taaactctaa acacatttaa
    10021 atataaattt atatatcatt ttgacttggt taaacaattt catacttatc gatataaaaa
    10081 taggttataa tataaatgtt cattatctta taacctattt tatataattt attcctaaaa
    10141 catgtgaatg ttttttatga tagtttgaag aaattataaa atcactttat aattgaatat
    10201 tatatataaa ttaatttaaa tatagaaagg aaaatatatg tacaacaata tcaaaaatat
    10261 tttaaaagaa aatcatataa cgtttgaaga atatgaccat gaacctattt tatcatttga
    10321 aaaagctaaa gaaataagag aaaaattaca atatactgga gtagaaagta aaagtttatt
    10381 tataaaagat agatctggaa attactatat atttgtaacc acagaaggaa aaaaattaga
    10441 tccaaaaact ataaaaaatg ttttaggtgg aaaagtatct atatgttcaa aagaagaatt
    10501 aacacaaaaa acacaatgtt tgcctggatg tgtatctcct tttggatatg agaaaaatat
    10561 ctctcttgta atagatcaag atatatttaa ccatgataaa ataatctttt caccagggat
    10621 accagaaaag acatttatta ttacagctag tggatttaaa aaagtaataa acaatataaa
    10681 caatacaact tataaatata tatattaatg aattttaatc ataattgtaa attagagaaa
    10741 ataacattag aaatcatgct taactatagt gtaaataaat tatattcaac acaaaagatt
    10801 gatactatta ttacaatagt tactgttaag ctcaaattca atgtattatg agttattatt
    10861 tttaaatttt aattacaaaa gcagggtagt tttaactact ctgctttata tttaacataa
    10921 aatatataaa atcaacaaaa tgattttagt ctatctatta gatattcttc gctctcaatg
    10981 cttaaaactt ttagatatat acaataagtg ctttcatttg taaaaatttc tatagtatta
    11041 tcttgtttat ttacacctac aatatcttta aaattgatat gatttttagt atttttacat
    11101 ttgaaaatat atctgttatc aatcaaaatc tcatcattag taattgaaat atagggttta
    11161 tctcatgctt tattaaaaat ttatatgttt gctcaagata aaaacttaca aataataata
    11221 gaaaagttac tttaaatgta catattatcg aaaatattat cacaaaaata cttataatat
    11281 atatttgttt aaaataacct ctatcgcaat agtttattaa cgatatggaa ataaaagtgt
    11341 taaatcagat tttggagaaa taactttaaa tatttccaga ctctttttag acagcctcca
    11401 taaccttata ttgaacctat ttattaactt tgtacttaca gataccattt atataagttt
    11461 cgtgtatatt aaagtcatta tctgttacta taaagtctgc atccatacct tgatatatag
    11521 agccacagac attatcaata ttacaactta aagcagggac atatgtagcc atttttattg
    11581 catcttctaa agttgatatg ttccaatcaa ctatatttct cacagccttg tccatagtta
    11641 atacacttcc agctaaactc ccactattta atcttgcaac actatttttt acatttacat
    11701 taaacttacc aagagtatat tttccatcct ccatagcacc agctctcata caatctgtaa
    11761 ttaaagctat gttattacta gacttcgcat ccatcattat tttaacagct attgggctta
    11821 catgatgacc atcacaaatt aattcagcat aagtatcttt tagtaccata gcagccccaa
    11881 ccattccagg ttctctatga tttaaaggac tcatcccatt atatgtatgt acaaacactt
    11941 tagcacctga attaacgact tgtttaactt gctcaaatgt agctgaacta tgaccaagag
    12001 aaactgatat attattttta gttgcatatc ttgttaattc tattgaacct ttacgttctg
    12061 gagcaattgc tatttttctt attaaatttt tcgatttttt ttgccataat tttaatatat
    12121 tgatgtcagg gtctttaaaa tatttttcat tttgagcgcc cttatatttt tctgtaaaaa
    12181 atggaccttc taaataaata ccttgtattt ttgcaccctc aactcgattg aagctattgc
    12241 ttatattttc tacagaatca cttagtgtat ctacagaatc agttaaagtt gtaggtagga
    12301 aagatgttac tccatatttt aataagcctt ttgaaattgt gtttattgct tcaaatgtat
    12361 tgtccatgac atctgcacct aaaagaccgt gaatgtgagt atcaactaag ccaggagcaa
    12421 tatatttacc tgaaaaatct ataacattat cagtaacatt aggtctttct tgttgaaatt
    12481 caccgaattt gccattaatt atactaaggt aacctttttc tttgattcca tgtttcataa
    12541 aaaatttatc tgcataaata aaacttttca aaataacctc cttataatta tactatcatt
    12601 gtggcattga cgtttataat atcattctat tttcttgaaa gttatttaac ttactatctt
    12661 acatgtctta ctctatatac aaatttatcg cttctagcaa cactcaaagt aaattcaata
    12721 actatattgt catcattata tgtggtacga agtaatttca gacaaggtga atctcctggt
    12781 acttccaata acttagcttc cttatcagag attattccag ctgaaaattc ttcatcagca
    12841 actttaataa tctcgccata atcttctcta aatatttcat ataaaggttt ttgttcgatt
    12901 ttttcttttg tcaatcctat aaattctttc ataggaagat atgttctttc aagcatcata
    12961 ggaaggtcat cagcaagtct taaacgcatt atttttatca ttttttcacc aggagttata
    13021 cctaattttt cagagaaata ctttgtactt tctactacct caaatgataa tacctttgta
    13081 cctggctttt ttccttgtgt tctcatataa tctgtaaaac tataactttc cattaagttt
    13141 tgagaatttt gacttagtgc agcaacaaaa gttccttttc catgtctttt gtatatatac
    13201 cccatatgtt ccaactcagc catagctagt ctaactgtgg ttctacttac tccatattca
    13261 tcacaaattt ttctttcgga aagcattcta tcgtttggtt ccatctcatt ttcaatctta
    13321 gttcttaata tctcaacaag ctggtcatat attggtcttt tatcatttct ttttatcata
    13381 aaaatatagt cctttctaag tggttattac cacaatttga ttatagaata tagaattatt
    13441 tatgtcaatg aataaagttt aatcaaaatt caataagtaa ggttattaat ttattataaa
    13501 attatggtac attgacaaaa caagtaaaat aatttatatt caaattggta ataaccactt
    13561 tgggtatatt atagatgagg tattttttat tttacagatt aatttattgt ttagaaaagt
    13621 aaaaattaat aatgaggaga atctagtatg attacagtaa taacattcaa cccatctata
    13681 gatagaatgt atagagtgaa taatataaac ataggtgagg tgcaaagggt agtaagtaag
    13741 aatgcaactg ctggaggtaa aggattaaac gtagctaagg tatgtaaaat tttaaaagaa
    13801 aatcctttag ctatgggatt tctaggcgga tttaatggag aatttataaa aaatgaactt
    13861 agaaaactag atatacaaaa taaatttaca aaaatagagc aggaaactag aaattgctta
    13921 aacataattg aggacaataa agttagtaca gaatttttag aaaaaggacc aatagtagaa
    13981 aaaagcgatt tagagagatt tgaaaatgat atagaggaag tactaaaaaa tactaaaata
    14041 ctggtagctt ctggtagtta ttgtgagaat atgccgatag actattatga aaagatagga
    14101 aatatatgta gagcaaataa tataaagttt atattagata catcaggaga agcattaaaa
    14161 atagctttaa aatcaaaacc atatttaata aaaccaaata tagatgaaat aagacattta
    14221 ttaggaatga atatagaatc aagagaggaa attatcttgt caggaaaaaa acttattgaa
    14281 atgggtgcag agaatgtatg tatatcttta ggaaaagatg gtatggtgta tttaaacgaa
    14341 gataatgtat atgatgtaaa agtaccagtt gtaaagtgta taaatactgt aggtagtgga
    14401 gatagcacag tggctggatt tagtgtaggt attttaaggg gttataaaat agaaaattta
    14461 cttaaatttg caaatgcttg tggtataagt aatgctttaa atatggaaac tggatttgta
    14521 gatttgggag aaattgataa atatcaagat ttagttgaag taaaaaagtt aagttaaata
    14581 catttaatgg gaatataata aatttaatgt tgttgtaata gattttaatt ttaatataaa
    14641 agatatagtc ttatataaaa ataggttaga aaaattcatt tttaacctat ttttataata
    14701 aatatctatt ttactgaatt tataattttc tctagtaatc tttgagcttt gatacactct
    14761 tctccattaa tagctggttt tatattattt tctatacaat caataaaatg atttgatata
    14821 tcctcaaaac ccttttgttt taatatattt acccatgcac cactttgctt taaagttagg
    14881 tttccacctt cttctatttc cagtacatta agattcttaa ctctttgaat cttacccttt
    14941 gaaagaattt caacttgttc taactttgtt ccagaatctc tatgcataga ggtgtttata
    15001 gagaaatttt tacctttaag tttatgactt acaaatataa gattcttatt gtctgttaaa
    15061 aataaatcct ctccactaat ttcaacatct tcatttgcta accataaagc agtgtcaata
    15121 acatgtatat agtcatctat aagagtactg tcgaatctaa catttcttaa ggaatttaat
    15181 ccatgtttac atatattgat agatacaatt tctgtagcat tatttttaat ttctttgtac
    15241 ataggacaga atctacggtt gaatccaacc attaaattta agtttttttt cgtacttaac
    15301 tcgataagtt cttctccttg acttactgtt gaagcaagag gtttgtctac atatacatga
    15361 acacctaaat ttaataatat ttttataatt tcgtagtgtg tttctgtaga gctatgtaga
    15421 aaaatacaat cacatttttt agctagggat tcaatagaat cgaatggcat gattctataa
    15481 tcactacaga ctttttccct tttaacttta tttggagtaa aagctcctac aaactcaaat
    15541 ctctcagact tagttaatat aggtaaatat gccttttgag ctatggagcc aagacctatc
    15601 attcccattt ttatattttt cataatactt tctcctaagg tttttatatt tacagaattg
    15661 attataattc agacacataa atttgtaaac tttgtatcaa aaaataaatt taaagcttat
    15721 ataagtaaat tagcgaaata agaaatattg ataaagtaat tttgtaggat atccataaaa
    15781 ttgattgata taaatatttt atgtattgac aaaaaattca aattaattta tatttggatt
    15841 agtggtaatt accactttgg tctgaacaag cttttatcgt aaaataaaaa tactaaagta
    15901 tatagagtat gattttatta aatttttaaa gataaactat aaaattaatt aaaatctata
    15961 gtgtatattt tatagtgagt ttaagtagta ctaaaaaatc taagcaaaaa attataaaag
    16021 agtatatttt tttatagttt aaagtggtta taacctcatt accaaatgta aacgttacaa
    16081 gtatgaaagg agaatgaaaa tgtttaaatt agaagaacaa aaactaaaag atttaggtgc
    16141 aataataaca actaatgaaa taaaacaaca gcctgaatta tggttagaaa cttatgaaat
    16201 atataaatct aacaaagaaa aattaagtag attcatagat acaataagta ataatcatgg
    16261 gcagtttaga gttatattta caggtgctgg aacttcagct tacataggaa attcaatact
    16321 tccttacctt aaaaataaaa atgacataag aaaatacata tttgaagcaa tacctactac
    16381 ggatatagtt tcaaacccat atgattactt aaaaaaagat ataccaacat tattaatttc
    16441 atttgcaaga agtggaaata gtcctgaaag tttagcagct ttaaatttag ggaataagat
    16501 tgtagataat ttttatcatt tagctataac ttgtaatcca gaaggagaac tggctaagat
    16561 gactaaaaac gacgaaaata attacttgtt attaatgcca tcaaaatcaa atgatgaagg
    16621 ctttgccatg acaggaagtt tttcgtgtat gatgttatct gctatgttaa tattcgatag
    16681 tttagaagat gatgtagaaa agtcatatat aaatgcaata attgaaatgg gaagaaatgt
    16741 tatagataga aaagatgaaa tacatgagtt aataaataaa gattttgata gagttgtata
    16801 tttaggttca ggaggattag gtggtttgac acaagaagca caactaaaac ttttagaact
    16861 tacagcagga aaaatatcta cagtgtatga ttctcctatg gggtttagac acggaccaaa
    16921 atcatttatt gatgaaaata cacttgtatt tgaatttgta tctaactgtt tatatacaag
    16981 aaaatatgat ttagatgttt tagaggagat aaaaagggat aaaattgcta aattcacttg
    17041 tgcagtgtca gtagaaaatg aaaataactt ctcaggaaca aagtttgagt ttaaagaaaa
    17101 gtataataaa ttaccagatg tgtatcttgc aatgccatac atattgtttg cacaaactat
    17161 agcattgttt gtatcagtaa aggttggaaa taagccagat actccatcag ctacaggaac
    17221 agtaaatcga gtagtaaaag gtgtaacaat atatgaatat taaaagataa gattaaaata
    17281 ttataactaa ataatttggg agggtatcaa tgtggcatta gtaacaacaa catcaatgct
    17341 taaaaaggca caagatgaag ggtatgcagt aggagcattt aatgtagaaa atatggaaat
    17401 ggtaattgct gttatagaag ctgctgagga gttaaattct ccagtaatat tacaaactac
    17461 tccatctact gtaaaatatg caggtcttga ttattatcta gcaaatgcaa aggttgctgc
    17521 agaaagagta aatatacctg tagcaatgca tctggaccat ggttcaagtt ttgaccttgc
    17581 aatgaaagct ttaagaagtg gatatacatc aataatgata gatggttctc atgaaagctt
    17641 tgaaaataat atatctatat ctaaatcagt agtaaaagca tgtagtcctt ctcttatacc
    17701 agtggaagca gaacttggga aagttggtgg aaaagaagat gatttagatg gcgggaatag
    17761 taatgattat acaaatccaa aagaggcaaa agagtttgtc gatagaacag gaatatcttc
    17821 attggctatt gctataggta ctgcacatgg attgtataag ggtgaaccta aaatagattt
    17881 agataggtta tcagaaatta aaaatgtagt ttcaatacct ttagtattgc atggaggttc
    17941 aggaatacat gatgatatta taaaagaagc tataaaaaga ggtattgcaa aagttaacta
    18001 tgcaactgaa ttaagaattg catatagtaa aggggttaaa aaagttttag atgaagattc
    18061 tgaggttata gaccctaaaa agtatggatt agcagggctt caatcagtaa aggattttgt
    18121 gaaagaaaag attaaagtgt gtgggtctgt aaatagagta taaaaataaa atatcctaaa
    18181 tttattttag ataagtttag gatatttatt atatgaaaaa tttatattaa ttatatgtaa
    18241 atggtgtatt tttttcattt aattgatgaa aaatatcagc ttttattggt aaagtattac
    18301 atatataatt aaaatatact aaaaattgaa ctatatattt tattattata aaatatttat
    18361 attaaattgt ggaattaaaa tatactagga tataaaattc ttaaataaaa agaaaaggtt
    18421 gtttttataa aaaatatttt ttataccact ttaaaaaaca caataataac actgagggag
    18481 gtggggatat gagagaacgc attattcttg aaacattaaa aaatagtagt ggttatctaa
    18541 acatagatta ttttgcagat aagttggggg tatctactcg aactatcaga aatgaaataa
    18601 aaaagataga aactataaaa gaatgtaatg gttttaaatt agaatataag tctaaattag
    18661 gatatattct aaatattaaa gaccaagata aattcgagca ttatctaaga aacttaccct
    18721 cagatttagt tgaaaatcca gaacaacggt tggagtctat aatagtagag cttttagtaa
    18781 atgaaggtta taaaactata gaacagttaa gtaaaaaatt tctagtaagt tcatcccaaa
    18841 taaaaaatga tttaaaaaag atagatgaaa agataaagga tacagaatta aaactagagc
    18901 gaaaggctca ttatggaatt aaaatagaag gttctataaa agaaattcaa agtatattgg
    18961 tggatagtta ttttagaggg aatagaaata taacagagta caggaataag tttatagata
    19021 atttaaaatt agctaatatt agaagtacaa taaaaaatgt acttaatgaa catgatttag
    19081 aagcaaattt aacagaactt gaggaaatat tagcacaaat tattatattg tatataagag
    19141 ttagtatgag agtagtggga aatgctagcg atttaaaatt atatacagaa gatttaatta
    19201 tagataaatt attagataaa atttttagag ataaaaaata taaccttaat tatgatgaaa
    19261 agtattattt aaaggagctt ataaaactaa agactaaaga taagaaagcc actataaaga
    19321 atattgataa gaataaactt caagatatta tgttcgaatt ttttagagag atagataaaa
    19381 aatataactc taatttttta gaagataaag agttttttaa cttattttac ttacatattg
    19441 catgtttaat agaacgtata aagaagaacc acaagataat aaatcctttt tcagttaaaa
    19501 taagtcaaca gtatccaact gtttttaatt tatctattca attttcaaaa atcatagaaa
    19561 atgagtatca tataaaaata agtcaagatg aaatagggtt tatagctact cacattgctg
    19621 ttccttttga aaagagagaa gaagctaatt ttaataaaaa atataaaata gcaataatat
    19681 gctcttctgg tggaggtagt gcatttttga taaatttaag acttaaagaa atttttccaa
    19741 atgctgagat aagaaatttt tcattactag aagaaaaagc tgtaatagaa tttgcaccag
    19801 atttgatttt ttcaataaca aatcttttat ttgaaataaa tgctccagtt atacttataa
    19861 atgaaatttt agacgaattg gattatttag atattaaaga aagtgttaga tttgcagacc
    19921 atataggaaa tatatcaagc ccaaaacaat atatattagg tctatttgat aagaatcact
    19981 ttaggtgtat aaaagataaa gctaagtata aggatatcct tgatagtatg tcaaaatgta
    20041 tagttgacga gggagcttgt tctccaacct atcccaaaga tgtatgggaa agagaaagtt
    20101 atttgagtac tatttataca aatggggtgg ctatacctca tccaatcgag atgacaggaa
    20161 acaaaaatat aatatcagta gctttgatac aaactgatat tatttatgaa aatagggtgc
    20221 ctaaaattat tttcatgatt tcattaataa agggaaattt agaacttcat aagcaaatat
    20281 ctaaatattt aagtaagatt atggcaaata aggatatggt agacatgcta aataagtcac
    20341 aatcttatga agagtttatg tataagttaa aaatctatct gggaggttag acatgaatat
    20401 agagtttttt aagaggttgt cagaagcaga tggtatagca tctaatgaag aagaggttag
    20461 acatgtttta ttggaagaac taaaagctta tagtgataaa attatctgtg atgggctagg
    20521 gagtatcatc ttttctaaaa taaaagatga gagtgcacca aacgtaatga tttgtgctca
    20581 tatggatgaa gttggattta tggtgagaag tatagacaaa cttggtatga ttcacttaat
    20641 aacaatagga ggagtaaaac ctcttgcaca gtttgtacaa aaagttagaa ttacaacaaa
    20701 agaagggaag aaaatccccg ctgtcataaa tgctacatat aataatggta aggctgaaaa
    20761 tatatatgca gatattggag catatacaga agaagatgta tataacctag ggattaatgt
    20821 tggggatatg gtaacatata caacaagctt tgaggaattt actttaccag accgattagt
    20881 gggaaaggct tttgatgata ggataggatg ttttgtgatg ggagaagttt taaaagaact
    20941 taggaaagaa aatctaaatt gtaatattca ctttgcggct acaagtagtg aagaggttgg
    21001 aataagggga gcaaagacat caacacagtt aataaatcca gatatagtat ttgtaataga
    21061 tgtagcatgt gctaaaaatg agtttgtgag agactataca aataagaaac aaattgataa
    21121 aggtgtaatg ctaatgcata gagataggac tctagtccct agtagaaaaa tgatagatta
    21181 tgtaatggaa attgctgata aaaataatat accacttcaa catgatatgt ttgaatcagg
    21241 tgggactgat ggaggagaag cacatctcgt aaatgaaggg aaaccttgtg tagtaacttg
    21301 tgtaccagtt agatatggtc attgtgcatt ttcaatagta agtaataaag atttggagaa
    21361 cattataaga ttgtatacac agttaatttt aaattttgat gaagaacaat ataaacatat
    21421 aagaaatttt atctaaagga gaataagaaa atgtcaacag aagtacaaat aatggaactt
    21481 atatcaactg caggagagag taaatcgaaa gcttttgagg ctttaaaaaa agtgaagtca
    21541 aaagatttta aaggagcaaa attgttaata gaggaggctc gtaaaataga tattgaagct
    21601 cacaggatac aaacagaatt aataactcaa gatttaaatg aagatgttga aagtccagca
    21661 atgagtcttt taatggtaca tgctcaagac cactatatga cttctcagct agcaaaagac
    21721 ttgatagagg ctttgatata ttgtcttgat aagtaattgt aatatagaaa tagattattt
    21781 atgtaaaaat tcttttaaaa gtttagatgc ttttaagaga taataaaaat acaaacttta
    21841 ggaggaatta ttatgaaaat attattatgt tgtgcaggtg gattttctac taatatgtta
    21901 atgcaaaata tgaaaaaggt ggtaaaagag agtgctaaac tcaatgaaaa agattttgag
    21961 tttacagcta taccagcaga ttcaatagaa agtgaagttg atgattggga tatagtactt
    22021 ataggtcctc aaatagctca caaaatagac ttcttaaaag gaatattaga gccaaaaaat
    22081 aagccttttg cagtaataga taaagatgta tatggaaaaa tggatggagc tacagttatg
    22141 aagttggcat taataactta taagaaacat caattagctc aaggataata aaaataatga
    22201 gggaaaaggg agattagata tgttttcaaa atttgaagca tttatgaata gagtatttat
    22261 gcctttagct cataaggttg acaatcaacg tcaccttggt tctataaagg ctggtatggt
    22321 tgctatgaca ccattcacaa tattaggaag tatatttgca atacttccag cacttccaaa
    22381 tatgcttgga gaaaataatc caataagcaa attcatactt agcaattcag caatattgga
    22441 tttaccagta agtctttcca taggtttaat aggattatat gcttgtatgt gtattgcttt
    22501 taatctgggg aactactata aattatatat accaggttgt gttgcactat caactttttc
    22561 ttttttattc ctagtagcct catttacacc agatggagct ttagaaatag gaaatttagg
    22621 agctaaaggg ctatttacag gtatgatagc agggcttggt tctgtggagt tatataattt
    22681 ttgtaataag aagaatatca caataaaaat gccagaaaat gtacctgatt ttgtatctag
    22741 gtcttttgaa ttaataccta ctactataat agtttgtgga acttttatag ttgctcgttt
    22801 tatttcatta aaagtatttg gagaattacc tccacagata cttactcaat ttttatctcc
    22861 attagtagga agtatggata acccatggtc agttcttgca cttaactttg ctatatgtac
    22921 tatattcttt tttggaatac attcatcagt atttagtcct ataactagac ctataatgat
    22981 tacatttata gctgaaaaca tagcagctat gcaggctgga gaaacaatac ctcatttctt
    23041 tacagcagga gcttcaagtg cattctttgg atttacagga tgtggaatta gtataggttg
    23101 tgtaattgca tgtatgttat caaaaaatgc ttcctataag aagattggac gtgtatcatt
    23161 attccctgca ttatttggga taaatgaacc aatattattt ggagcaccga taatattaaa
    23221 tccaataatg tttataccac atgtatttgg tggagctata ataggtacac taccaatgtt
    23281 ttttatgcac tggggatggt tagcaaagcc agtatttgac cctccatatg taggggtatt
    23341 cttagaagga tttttaacta atggagattg gcattctata ttagcaaatg cattgcaatt
    23401 agtattagca gttttattat attggccatt ctttaaaata atggaacgtc aacaaaataa
    23461 taaaaaacaa aaagaagaaa ctaagaatat attctctaaa gaagaagaag gcttattgga
    23521 tgatttagga ttggatttct aatattttgt tatgaataat acaatggaga gattagtatc
    23581 cttaatctat aaaagaggtg ttgacgctct tttgattaaa gcaaaaaata ctaaaagata
    23641 tataggagct ttatcaggta gtggtgtata tgtgcttgtt actaaggata aaaattatca
    23701 aattctagat ggcagatata ttgatgaagc agataaaaaa acgactggtt tcataaaaag
    23761 gattgtatct caaggttctt atataccaac tataattgag ttattaaaag aattaaatat
    23821 aaaaaagtta gcaatagaaa accaagctat gagtatacaa gagtatcttt cactaaaaaa
    23881 tgaaggtttt gaaatcaatt taataacaaa tgaattatgg aagctaaggg ctataaaatc
    23941 taaagaagaa attaaactta ttaaaaaggc ttgtgagatt acagatgaag tatttgatga
    24001 ggttatttct gaaattaaaa aagatatgac tgagctagaa gtatcagctc taattcagta
    24061 tcatgcatta aaaaaaggtg caagtggaat gtcttttgaa acaatagtgg tatcaggaga
    24121 aagaggtgca atgccacatg gaagacctac aaacaaaaaa ttgaaagtga atgaagctat
    24181 aacaatagat tttggtgttg tttatcaagg gtatcaatca gacatgactc gtacaatatc
    24241 tataggcaaa cctcctaaaa ttattaaaga gatatatgat gtagtattgg aagcacaatt
    24301 atctgcaata gagtcaataa aggaaggaac tagggcaagt gatgttgaca aagtggctag
    24361 aaaaattata gataaacatg gatttggcga atattttaat catggactgg gtcatggtat
    24421 aggtcttgga gatggtgaag ttcccacttt aaatccaaat agtgaagata tattagtgga
    24481 aggaatggta atgtcttgtg agccaggtat ttatattcca aatgtagggg gagttagaat
    24541 agaagatgat attgttataa tagatggaaa aggtgttcca ctcaataaga catccaaaga
    24601 gtttataata ttaggagagt aaaattatga aatataattt taataaagta ttaaatcgta
    24661 aagaaggaaa ttgtagaaaa tggagcaacc atgtgattaa agaaaaattt ggcttaaatg
    24721 aagatgcaat tcctatggat ttagctgata tcgattttga gtgtgctcct gctataaaag
    24781 aatctatctt aaaaagagca tcagtaggag attatagtta tacttttata ggagatgact
    24841 tctatgatgc tattataaat tggaataaaa gaagatttga tgtatatata gaaaaggatt
    24901 ggataaaatt aacttttggt actgtttcaa cccttcatta tatagtccaa gcatatacta
    24961 aagaaggaga gggtgtattg ataaatacac ctgcttatga cccttttgca gaggctgtag
    25021 taaataataa tagaaagttg tgttgtagct cattaaaatt agataacaat agatattatt
    25081 tagatttaga ggatatggaa aatcaaatga aatacgagaa tataagattg cttatattct
    25141 gtagtccaca aaatccatca ggtcgtatat ggacaaaaga agaactatat caagtgtcag
    25201 agttatgttt aaagtataat gtaattttgg taagtgatga aattcataga gatataatat
    25261 ttaaagatta tagatttgta tctttgtgga atgctcatcc agaaatttat aaaaatagta
    25321 taatctgtgt atctcctaat aaaggcttca acttaggtgg attaaaaaca tcatatgtat
    25381 taataagaga tgtaaaaatt agggagactt tattagaaag gctaaaaagt aattcaataa
    25441 cttctccaaa tgtatttgca ataccagcaa tagttgcagc atataatgaa agcgaagaat
    25501 ggctagatgc tatgactagt tatgtagagg agaattttga aatagtttat gatttctttg
    25561 aaactaatat accaaaagct aaagtgatga agtcagactc ttctttttta gcctggatag
    25621 atgtaagaga agtatttaga aatgaagaag aatctaaaga attttttaga catgcaaact
    25681 taactatggt agttggaagt tattttgtga aagatggaga tggatttatt cgtattaatg
    25741 tggggtgtcc tagagaaaca ttaaatgagg ctctaaatag aatcaaaaaa acgtatataa
    25801 gtatgtattg ttaaatcata aaaaaagtat ctatggttta tataaaaaca cattatttag
    25861 ttatcaaata ttactggaat tttgtattcc agtaatattt tttgattaag gaatattatt
    25921 gaggaatatt aaataatatt atttcatacc cttatattaa cttatataaa aatattttat
    25981 tattttggga acgggttagc taacctttat ctagtgtata tttatattgt aagaagcagt
    26041 aaaaactttt cctttactaa gtttattaat aaacttctta tctttataaa ttttgttaga
    26101 atttatacta tcagcaagac cataccaagg ttctatacat aaaaaaggag cagtagaatt
    26161 agtttcacta taataaggag tccaaatacc aactagaggg aaatcttcca tagatatagt
    26221 tacatattta ctaccatcat tattacatat agacacttca tctatgttgg tgtatatcaa
    26281 agcatcattc ttgaatactt ctggatttaa ctgtaagttt tttaattttc caataggtat
    26341 tatatcatct gtaaaagaac catttaaatt gattttttct acatcatttt tacttttaaa
    26401 ctcaaggtag tgtttagaaa aatcattttg ttcgtaaaaa ggaaggttga atgcaggatg
    26461 tccacctata gaaaagaata tatctttaga atcagtattt tttacaatcc attctacctc
    26521 aatactatta tcatttaatg tatagtttat gattagctca aaagaatatg gatacttctt
    26581 taaagtagat tcattatctg ttaatttata agttacaaat gtatctcctt tatctacaat
    26641 ctcaaagtcc atatctctag caaacccatg ttgagtcatg ctatataaat tttcttctat
    26701 tattgtttca ttatcaaaaa gtttacctac tatagggaac aatataggtg attgtctacc
    26761 ccaatatttt ttattaccat cccaaagaat gtttttgtcg tattttttag aaaatatttt
    26821 agttagttca gcaccaaaac tgcttgattc gataattaaa ttttcatttt gtaatatatt
    26881 catttaaaat ctcctttatt atattttatg agtatattat actataaagt ataaagatta
    26941 ttaaatttta tttgatatta tatttgaaag gtagatttta gtatattttg aaaattttgt
    27001 tttgaaaatt tgggattatt taagaaattt tgtattataa atagaaggaa atagataaat
    27061 tgtatagaat aaaatatatt aagataagtt aataatgtta aatgggaagt gagtttatgg
    27121 aaaaaccaaa tacaaaagtt gttaactttc aagagtataa agacagaaaa aaccaaagag
    27181 aagtaaatag agacgaactt ttaaagctta taaaaaaaat tgtgacttca aaatagggag
    27241 ttgttaaact ccctatttta atgggtttca taataattaa gacattctaa gtccatctat
    27301 ataatctttg aattgtgaga aatctgattc actacttaat tctatggttt ctgaaccttc
    27361 cgtataaaaa ttcttaagat agatagtata attattatca acacaatcat gataaataca
    27421 tctatatcca tcttcataca aactttttaa cttagaaaaa tcatccacaa tatcatctcc
    27481 ttaaagttct tttaaatata tttttacaaa aagcatctaa ttgtatgcaa attgacaatg
    27541 taaaataaag gaaatgaaca taaaatgtag aataattttt atatgtatgt aaaaataaaa
    27601 agaaaaagtt gaaattttta gaaaataaga gtatttttta tctaaaaaga gagtttaaaa
    27661 aataaaaaaa tgttgggagg ataaaaaatg agtttattag aaagtatatc aaaaaacata
    27721 tattccctag ataactcttc tattgaaaaa acaaagcaga gattggatag gcttatacat
    27781 ccaactggaa gcttaggaaa gatagaagat atttgcatgc aattagcagg aatatttggc
    27841 aatgaaaatt ttgacacaag taaaaaggtt ataattgctt ttgcgggaga ccatggtgta
    27901 tatgaagaag gcgtagcacc tgaccctcaa aatataacaa aattacagtt tccaaatttt
    27961 tcgaaaggtc tatgcggagt tggagtaata agtaaatttg taggggcaga tgttgtagct
    28021 gtagatgtag gaataaactg tgatgaaaaa ctggatgggg tattagacta caagataaga
    28081 aaagggacat caaatatggc aaaaggtcca gctatgagta aacaagaagc aattagatgt
    28141 ttagagatag gtattgaaat agcagagcag tgtatagaaa aagattataa ggttattggt
    28201 attggggaga tgggtatagc aaatactact ccaagtacag caataatatc tgtaatttca
    28261 gggtgtgacc cgttagaagt tactggtata ggtgcaggtc ttaagaaaga aagactaaag
    28321 cataaggctg aagtaattag aaaggctatt gaaattaata atccaaatcc aactgatgga
    28381 gtagatattt tatctaaagt aggagggttt gaaataggct caatggcagg tgttatatta
    28441 ggttgtagtg ctaataggat tccagtagta attgatgggt ttatttctta tgcagcagca
    28501 ttaattgcat ataagataaa tccaaaaact agagaatata tgatagcatc tcatttatca
    28561 gcagaatcag gaactaaaag agcattagac atattaaaat tagaccctct attaaatatg
    28621 gatatgagat taggtgaggg aagtggagct gctttagcat ttgatataat agaagcttca
    28681 aactatactt ataaaaatat ggcaactttt gatgaaattg acatgggaag ataaatataa
    28741 aaatttaata tgtaggagtg ttttgatgag taaaattatt ctagtaacag gaggagctag
    28801 gtcagggaag agtaactttg cagaaaaact atgttttgac agaaataata atacagctta
    28861 tatagcaacc tctattccat ttgatgatga aatgaaagat agagtaaaaa aacatcaaga
    28921 gaatagacct agaaactgga atacttatga aatatatgaa gatatatatt ccataattaa
    28981 ggagatatat aaagaacatg aaactgttat actagattgt gtaacattat tagtaaataa
    29041 tctaatgttt gaacacaatc taaatataga agaatctagt caagaagaaa taaacaaatt
    29101 agaacaatac ataaaagaac aagttgtcaa acttattgaa gaaatagaaa aaacaaatct
    29161 atactttgta tttgtaacga atgagttagg tatgggaatt gttcctggga ataaacttag
    29221 tagaatttat gctgatattg taggtcgtat aaatcaatat atagcttcga aaagtaatga
    29281 agtttatttt gtagttagtg gcatagctat gaagataaag gagtagtatg caattatgaa
    29341 aagatttatt ttaatactac agtttttgac aaggatacct ataaaattaa atgtaggatt
    29401 tgatgatgaa ttttataagt caatagtata ttttccactt gtaggttttg tcataggtat
    29461 attatcctat ttaataggat ggatttctat gcttttattt gaaccattta tagcttctat
    29521 aataataact ctagctggtg tcttaattac tggaggactt catatagatg gattaggaga
    29581 tacatttgat gcaatatata gttataggga taaagaaaag atgcttgaaa taatgaaaga
    29641 ttcaagatta ggtacaaatt cacttctagc aattatgttt gtacttttat taaaggttgg
    29701 attcgtttac gatataataa gtaataattc attgtgggtt ataattttta tgccaatgat
    29761 tgcaaggtta ggagtaatgt tattgacata taaaactgtg acaccaagag aaaaaggaat
    29821 gggaaattta tttataggaa aattaactac aagtatgtta ataactgcta taatatacac
    29881 attattgata gttgctctta ttactaaatt tatattttta ttacctaata tagtgttgat
    29941 taaagtatta ggttcgatta tagtggtttt tgtatttata atattattca aaaaacatat
    30001 ttataaaaaa attgacggag taacaggaga tatattaggc tgtggaatag aactttcaga
    30061 gcttgtatat ttaatttaca tatatttgtt aatttttatg tttttttaaa gtaaaaagtg
    30121 gtgataatat gataagatta atattaataa gacatgcact gacaaatgat aataaaaaag
    30181 gaagattatc aggccatata aatagttgta ttagtgaaga gggcaaacta caaataaata
    30241 aaattaccag atatctgagt aatgaaaaca tagataaggt ttatacaaca ccatctacac
    30301 gtactaaaga tacagtagaa aaaatatcaa aattgaaatt attagaaata gaagaaaaag
    30361 aagctttaag agaaattagt tttggagact ttgaaggaag aacttttgaa gaaattaaaa
    30421 tcaaatatcc aaatgagttt gaaaaaatga taaaagaagg taacaactat agatatccaa
    30481 atggagaaag tttgatagac tcttataaaa gagtggcaaa agaaattgat aatataattt
    30541 tagaaaataa tagtaattta gatacaaaga caatacttat atgttctcat gcaggaacaa
    30601 taagaaatat aataacacat ttgatttctg gtagttataa gtatcactgg aactttaaaa
    30661 ttgataatgc atctattaca gttttagaaa ttgatggtgg atttgctgta atagataaaa
    30721 tgaattttac agacttcata taatttaatc aaaaccaaac attacaatct gtgtttgtaa
    30781 tatatctgta aaattagcaa tgaaaataga atattagatt aaaattaggt tcttaattag
    30841 atgttaaaag ggaaaaaggt tagatgcctt tgcagccccc gctactgtga aaccaacgaa
    30901 actataaata ccactgtcag tttgatggga aggttataga agtaggatga agttaagcca
    30961 ggatacctgc ctaatttaat ttaaaacaag aggtcttcgg ggtgaaagat ttttaattaa
    31021 tatatataaa agtcctatct ttagaagtat taggactttt tttaatttgt tttttagtaa
    31081 attttaacaa ggagggatgg aaagtgggga aaaaaataat gctacaagga acagcttcaa
    31141 atgtaggtaa aagtgtctta gtagcaggtt tgtgtagaat atttaagcaa gatggttata
    31201 ctgttgctcc ttttaagtca caaaatatgg ctttaaattc ttttataact aaagaaggat
    31261 tagaaatggg aagagcacaa gtatttcaag cagaggctgc gaaaatagag ccaatagctg
    31321 atatgaatcc agttttatta aaaccttctg gaaataataa aagtcaagtt attgtaagag
    31381 gtaaagttgt aggagaaatg ccttcttcta agtatcatga ttataaattg gagttagtag
    31441 atgtgttgaa ggaaacattt aatagcttaa attcaaggta tgatattgta gttatggaag
    31501 gggcaggaag taatgcagag ataaacttaa aagatagaga tatctctaat atgggtatgg
    31561 cagaaatagc tgatgcacct gtaataatag tcggagatat tgatagagga ggcgtatttg
    31621 cctcattagc aggaacaatg cttttattaa atgaagatga gaaaagaaga gtaaaaggtg
    31681 taataatcaa taaattcaga ggaaaaaaag agcttttaca agatggtgta aagatgctag
    31741 aagacatcat aaaagtacct gttataggag tagtacctta tacagatata aaaatagaag
    31801 atgaagacag tgtaactacg agatttaaga aaaaaatgaa taaaagtgat atacacatag
    31861 aaataattag aaccccacat atgtcaaatt ttacagattt taatatattt gagacacaag
    31921 aagatgtaag tataagatat gtagactatg gagaatcttt aggaaatcca gatatattaa
    31981 taatacctgg aactaaaagt actatagacg atttaacata tataagaaaa agtggtcttg
    32041 aatcgcaaat caaaaattta catagtcaag gtaaattgat atttgggata tgtggtggat
    32101 accaaatgtt aggtaaaaaa ttaaaagacc cttatcatgt tgaaagtgaa attgaagaag
    32161 ttgatggaat aggtctttta gatacagaaa caacgtttga gaaagaaaag actacaacac
    32221 aagtagaagc tactattgtt gaatgtatca gtgaatacat gaataacctt aagggaaaaa
    32281 aagtaaaagg ttatgaaatt catatgggaa ttacaaagcg aggtaatgat gtaagaagtt
    32341 tagatttaat aactaaaaaa cttgataaag aagtgaatta tactgaggga agtgtaaata
    32401 aagaggggaa tgtaattggg acttatcttc atggaatatt tgatgaaata agctttacaa
    32461 gagcaatttt aaacaatata agaaagaaaa aaggtttagg agaattagaa agcaaagtaa
    32521 actcttttaa tgaatttaag gataaagagt atgataagtt ggctgatttt ttaagagaac
    32581 atttagatat agagaaaata tatgagatta tgaaataatg atgaccttta tttataattt
    32641 aggtaggagg tgtattatga aaaaaatttt aattgcgggt actaatagtg gagtaggtaa
    32701 aacaacaata tcattaggaa taatgcaagc tttggttaag agaaatatga aagtacagcc
    32761 atataaagta gggccagact atatagaccc ttcatatcac acttttataa ctggaagaca
    32821 ttctagaaat ttagattctt atatgttaga tgatgaaaaa ataaagtata tagtaaataa
    32881 gtcctcaaaa gatgcagata tttcagtaat agaaggtgtt atgggcttat atgatggctt
    32941 tggaatagat ttagataatt gtacaagttc acatacttca aaggtattaa agtcacctgt
    33001 tatattagtt ataaatggta aatctatggc agcatctagt gctgctatgg tacttggata
    33061 taaggaacta gataaagatg taaatataaa gggtgttata gtaaataatg taaagactaa
    33121 tagccattat caaataatta agagttctat agaaaaatat tgtaatgttg aagtattggg
    33181 gtattttcct ccaaataaca aattctcttt ggaatctcga catctaggat tagttcctag
    33241 tgtagaaatg aaatcactaa gggaaaaatt ttatacctta gcagatgaaa ttgaacacta
    33301 tatagatatt gacagaataa ttgaaatatc agaaagtgat gaatttgaga gtgattttga
    33361 ttttcaaact ttgatagaaa ataataaaat aaaagaacat gttaataata aatcaatagc
    33421 tatagcatat gataaagcat tcaattttta ttatagagaa aatatagagc ttttagagga
    33481 acttggttta gaaataaact attttagccc tcttgaagat gtatcagtgc caaatgcaga
    33541 ttatatttat attggaggag gttttccaga aatatttgga aaagaattag aagcaaatga
    33601 gtcaatgaga acttccatat tagaagcaca taacaataat atacctattt atgcagaatg
    33661 tggaggactg atgtacctag gtgagaaact attgaatcaa gaagaacaag aatttaatat
    33721 ggttggaata tttagtggaa ttagtaagat gacatcttct ttaaagagat ttgggtactg
    33781 tattggtgta gccaaggaaa atactctttt atctaaaaaa ggggaatcca ttaaagggca
    33841 tgagtttcat cattcaatat ttgaaagtga tgaaaaatgt gtatattcaa tgagaaaaga
    33901 aagagatgga aatatagtag aagagtggga tggtggttat agtaaaggaa acactttggc
    33961 tacatatctt catactcatt tttataataa cttaaattgt atagaaaatt ttttgaaaaa
    34021 aggaaatgaa taaatgagta ttttatctat ttatatagga tatgtgacag acttaattgt
    34081 aggagaccca tattcttttc ctcatccagt gagatttatt ggtaaactta taaattttac
    34141 tcaaggtata ataagaaagg tctctaaaaa tgataggcag ttaaaatttg ggggatttat
    34201 attatggttt ataaccgttg gaataacata tttaacaact tatgctatag tgaagttatt
    34261 tagttttaat atattattga gtattgtagt gaatagtttt ataatttata caacactagc
    34321 cacaaaatgt ttaaaagacg aagcattaaa aatttataat gtattaaaaa ctgaagatat
    34381 agaaaaatct aggattcagc tatcttatat agtaggtagg gatactacta atttaagtga
    34441 acctgaaata ataagagcaa ctgtagaaac tgttgcagaa aatactgtag atggtataat
    34501 tgcgcctatg ttttatgcat ttattggagg agcaccactt gctatggcct ataaagctat
    34561 caatacattg gactcaacag ttggatataa aaataaaaag tataaagata ttggttttgc
    34621 atctgctaag attgatgata tagccaatta tataccagct agaatatctg tcattcttat
    34681 gacaattgga agtttctttt taaattataa ctataggaac tgttttaaaa tctctattag
    34741 agatagaaag aatcataaaa gtccaaattg tgctttttca gaaggtgcag tatctggtgc
    34801 tctaggaata caactaggag gtaccaacgt ttattttggg gaaaaagtat ataagccaac
    34861 aataggggat aagcttaggg agatagataa agaagatata attaaaacta ataaaattat
    34921 gtatgcatct tcatttgtat ctatgttggt atttacacta atatatgtgt tatgtaggat
    34981 gattttaatt aacttaatta tataaattat tgtttgttaa cttaaggggg acatagatga
    35041 aggatttagg gcatggtgcc aatgtagatg aaatggcaag attatatggg aaaaacccaa
    35101 aagaaataat tgattttagt tcaaacataa atccaaatgt attaccaaat ttagagagat
    35161 acattttaaa aggattagaa gagtgtagga attatccaga tataaattat acaaacttga
    35221 gagaaaatat atcaaaatat atagatataa atccagactt tataatacct ggcaatggtg
    35281 caacagaagt gatttatttg cttatgaaga gtattaaaaa aaaattggct ataataaatc
    35341 cgactttttc agagtataga agaagtgctg agttaaataa tttagatatt atagatttag
    35401 agttagattt agaaaataac tttaaactta atatagatat aataaaagaa aatataaaaa
    35461 gatttgatag tttatttata tgtaatccta ataatccgag tggtaatgtc caagatttaa
    35521 aggaacttgt tcatttacta gataaacata ataaggtact aataattgat gaaactttca
    35581 tggaatttgt tgaagatgaa agtaaatata gtttggttaa atatatagaa tcaaataaaa
    35641 atatatttat aattaaagct gtgactaagt tttttggtat gcctggttta aggctaggat
    35701 atggtcttac aagcaacact gaaattatga acaaaattta tgaacacaaa gagccatgga
    35761 ctatcaattc ttttgcagat atactatcca attttatttt tgaagataaa gagtatatta
    35821 aaaatagtaa agaatattac atagaagaaa gaaaatatat gttacaagag ttgagaaaca
    35881 taagaaatat aaaggtctat gatacagatg ctaattttat cttgataaga atatataaaa
    35941 aaacaactaa agaattgaaa aaagatttgt ttaagcaagg aaacatatta gttagagatg
    36001 catctaattt tataggatta gatgatagct ttataagagt ggctataaaa tctcatgaag
    36061 ataacaaaat tcttatagaa aatatgaaaa atttattggg tgattaaaat gaaatcttat
    36121 ggaatatgcc cagcatcttg tggagaattt gtacaaggta taattgatga tgaagaatat
    36181 ttatgttcat atgcaataga tatgtattct aaagtgtata ttgaagaaaa attagtagat
    36241 ataaatttag ggagatataa gtcaaggtta gcaattgaaa aggtatttga aaaatttaat
    36301 ctacctaaaa aatatactaa aaatatttct ttaaatataa atagtaaaat acctgttgga
    36361 aaaggaatgg caagttcaac tgctgatata ggagctacta taaaggcaac attatcattg
    36421 atagataaag atttaagtag cgaggagatt tctaaattag cagcagaaat agaaccaaca
    36481 gattctatat ttatagataa aaatagtata tttaatcctc taaatggaac tgttataaaa
    36541 tacctaggaa atctgaccaa tgcgaaagtt gtaatacttg aaccaaacaa agtactagat
    36601 actatgaaaa ttagattgag gcaagattat aataaattaa aagtagagaa taaagaagta
    36661 ataaaaaaat catttgctct tttagaagaa ggattgaaaa aaaataattt atctctagtt
    36721 ggagaggctt gtactttgag tagcttagca aatgagaata tagaaaaaaa agagtattta
    36781 aatgaaataa taaaaatatc aaaaaaatat ggagcatatg gagtaaatat tgctcacagt
    36841 ggaactgtag taggtatttt aattgataag tttatgaatg ataaaaagat gatagatgcc
    36901 ttatgtgaat ctaacataaa ttctgtctat aataaaattt atacacaaaa cataattaat
    36961 ggaggaatta agggggaaat agaatggaat acataaagaa tcctatgaaa atagaagaaa
    37021 aaagttttga attgatacaa gaaataatag acgaaattag accagattat aaatttaaga
    37081 ataatatcga agaaaaaata ataaaaagag ctatacatac tactgctgat tttgattact
    37141 tagatatatt aaaaatatca gaagaagcag ttgatagtat aatagatgca ttaaaaaata
    37201 atgcaagtat ttatactgat acaaatatgg ctcttagtgg tataaataaa agaaagttag
    37261 aatcattagg atgtaagtat aaatgtttag tggcagatga tgaaactgta aaattagcta
    37321 aagaaaaagg aattactcgt tctatggcag cagtagaaat tgcagctaaa gaagaaggaa
    37381 gaaaaatatt cgttttaggt aatgctccaa cagctttata taaagttatg gagatgaaat
    37441 cagaaggtag attagattta gatgcagtta taggagttcc tgtaggtttt gtaggagcac
    37501 aagaatcaaa agatgaagtt gaaaaaacag atataccata tataatttct aaaggtagaa
    37561 aaggtggcag taatttagca gcagcaatag taaatgctat attatatact atgtaggtac
    37621 ctatatggaa gaatatgtat atatagatgg aaaaaaatat agaagaggat atactacagg
    37681 ttcatgtgca acaggtgcat ctaaggctgc tgtatatatg ttgattacaa aaaatagaat
    37741 caatactata aatatagata ctcctaaggg gataccatta ctactaaaag ttgataatat
    37801 aaatatttct gatacatttg tggaatgttc cataaaaaaa gatggtggag atgatataga
    37861 tgcaactcat accatggata tttatgcaag agctgaaatt gtagctaaaa atgataagaa
    37921 caaagggtat cttactctaa aggatataga taatttaagc accaatagtg agtgtaaaag
    37981 tgagctctat aagtttatta gggtttatgg cggaactggt attggtgtgg ttacaaaaaa
    38041 aggtcttagc gtggatgttg gtaaacctgc tataaatccg actccactta aaatgataaa
    38101 tcatgaaata agaaagctta taggagataa ttttgaatct atacttggaa atgataaagt
    38161 tttaaaaata acaatctttg ctccacaagg agaaactgta gcaaaaaaaa catttaatcc
    38221 aagattaggt atagttggag gaatatctat aataggtaca actgggattg ttgaacctat
    38281 gagtgatgag ggttggaaga agtctctatc tatagaactt cagatgaaaa aagaacaagg
    38341 cttagataaa ataatattgg ttccaggaaa tcatggagaa cagtttataa gagaaaaatt
    38401 aaacttagat attaagtatg tagttagggt aagtaatttt ataggctata tgattaaaga
    38461 agctcaaaga ataggatata agaaaatctt aatggcaggt catataggta aatttataaa
    38521 agtatctgct ggtattttta atactcatag taaggtagca gatgctagaa gtgagatatt
    38581 agtggcaaac ttagctttaa tgggagctag atacgaattt ttaaataaaa taaatcaatg
    38641 cgtaactact gaagaagctg tagagctaat aaataatagt gaatatagag aagtatataa
    38701 tatattaagt aataaatgta gggagagagt aaagcaatac ttgaatgaag attcagatga
    38761 tattgatgtg gaagtaatca tattttcaat ggataagtct ttattaggta aatcggataa
    38821 tacagatgat ttagtggagg tctttatatg ataaacataa taggtctagg acctggtaac
    38881 ttagactata taacaaaaaa aggtgaaaat ttaatttcca cttctgatgt attaattggt
    38941 ggtaaaagaa atttagagtc tataaaaaat tttgaaggag aaaaaatagt tctggattct
    39001 aatttaagag aaattataga gtacataaat aacaataaag aaaagcaaat atcaataata
    39061 gcatctgggg acccactaat atatgggata ggtagatatc tatctaaaaa tattgataat
    39121 aagatgttaa acatggtttc tgggattagt tcattacagt acatattttc aaaaatatat
    39181 gtagatatga atgatgtata tattacaagt agtcatggta aagtaccaga ttttgattac
    39241 atattatcac ataaaaaagt atgtatggtt acagattcaa agataggacc aaaacaaata
    39301 agtagagaaa taatagatag aaatctaaat aaaattattg ttgtaggaga aaatctgtca
    39361 tatgacaatg aaaaaataac aatagcaaaa ccagaagaga taataagaat ggacaatttt
    39421 gatatgaatg ttgtggtgat tttagatgag gaatagtgaa tttataacag gtaaagttcc
    39481 aattactaag gaagaggtta gagcaatatc aataagtaag ttaaatttag taaatgctaa
    39541 aaacctcata gacatagggg ctggtacagg aagtgtaagt gttgaagctg catataatta
    39601 tcctaattta aaggttatat ctatagagaa aaatgatgat gctatagagc ttatagagaa
    39661 aaataaaaaa aaattcaact tgaaaaatat agaagtgata aaaggatatg ctccaattaa
    39721 tctagggtta aatgttaaag ttgagtctat ttttcttggg ggaacaggaa ataatctgga
    39781 agaaataata gaatggtcta aaaaaaatct cgttacagga ggaagacttg tagctaattt
    39841 tataataata gatacattta atcaaacttt aaaactgctt aaaaagcatg gatttaaaga
    39901 aatagatgta tgtgttttga atgtttctaa actagagaaa ctaggaaaag gtgaatattt
    39961 taaaccacta aatcctatat atataatatc ttgtgaaaaa ggggaaaatg atgatgaata
    40021 aagtacattt tgtaggagca ggacctggag ataaagagct gataacatta aaaggataca
    40081 aattattaag taatgcagat gtagtgatat atgcaggttc acttgttaat cctgaacttt
    40141 tggaatactg taaagaagat tgccaaatac ataatagtgc acatatggat ttacaagaga
    40201 taatagatgt tatgagagaa ggtatagaaa ataataaatc tgttgtaaga ctgcaaacag
    40261 gtgatttttc tatatatggt tcaattagag aacaagtgga agatttaaat aaattgaata
    40321 tagattatga ctgtactcct ggagtaagtt cttttttagg ggcagcatca tctttagggg
    40381 ttgaatatac agttccagaa atttctcaaa gtgtaattat aacaagaatg gaaggcagaa
    40441 ctccggttcc agagaaagaa tcaatacaat catatgctaa gcatcagaca tctatggtaa
    40501 tatttttatc tgttcaagaa attgagaaag ttgtgtctaa attactggaa ggtggatatc
    40561 caaaagatac tcctatagca gttatataca aagcaacttg ggcagatgaa aaaatagtta
    40621 aaggaacttt aagtgatata gctgtaaaag ttaaagaaaa caacataaat aagactgctt
    40681 taataatggt tgggagattt ttaggagaag agtataataa ttcaaagtta tatgataagg
    40741 atttcaaaca tgaatataga gggtaatatt gctataatct gtattacaga aaatggaaaa
    40801 aaattagctc taaagataaa ttctctagta aataactgtg ttatatatca agtaaaaaat
    40861 aaaaaaagta atttagttgt tgaagaaaca tgtgtgcata cagttcaaaa gaagttaagt
    40921 gattttgtag gagaaatatt tagcaaattt gattacatag tatttataat ggctacaggt
    40981 atagttgtac gaagtatagc accatacata ataagtaagt ttagtgaccc tgcaattttg
    41041 gtaatggatg aaaaaggcaa aaacgtaata agtttattga gtggtcatat tggaggggca
    41101 aacagcttga cacagtacat aagtagtctt attgatgcta atccagtaat aacaacagct
    41161 actgatataa atcaaaaagc ttccttagat atgatagcaa aaaaactaaa tgcacatatt
    41221 gataatttta gagaaagtgt aaaagaagta aattctatgc tagtgaataa taaatgtgtt
    41281 ggattatatg ttgatgaagg atatcaagtt gatactaggg gatttaaact tatagaaagt
    41341 aaggatgagt taagagatag tttttcaaac acatatatag aaaaattagt tgtagtaagc
    41401 aataaaataa attgtattga agatattgag aatttaaacc tagataataa atttgaacat
    41461 tgctatagta cccaaaaaat aataaaggta attccaagag atatagtgat aggaattggc
    41521 tgtagaagaa acacagatag tgaactgatg tataattcac ttgaagagtt tcttaataaa
    41581 caaaatatag atattagagc aataaacaca gttggaagta tagaactgaa aaaagacgaa
    41641 aaagcaataa ttgaattatc aaaaatattg aaggtgccat ttaaaacatt ttcagtagat
    41701 gaaatatcta aggttgataa tctttttgat aaatctgatt ttgttaaaaa aaatgtgggt
    41761 gtgtattcag tagcagaacc tgtagcatat cttttgagca aaggtaattt gttagttgaa
    41821 aaacataaat ataaaggaat aactttttca gtggggagaa taaaaatatg atatacgttg
    41881 taggaattgg accaggaagt aaagatacaa tgactttaga agcaataaaa gcaatagaag
    41941 attctgaggc tattgttgga tataagactt atataaaact aatagaagaa tttatacaag
    42001 gtaaagaaat aatccaaaat ggtatgaggc aagaagttga tagatgtaaa caagcagtgg
    42061 aggaagcaaa aaaaggaaaa aaagtagcag ttgtaagcag tggtgatgct ggaatatatg
    42121 ggatggcagg tcttatttta gaattaatat ctaaagaaga tgaagatata aaagtaaagg
    42181 taattccagg cgttactgca agtattggtg cagcagctat acttggagct cctattatgc
    42241 atgatttctg tcatataagt ttgagtgatt taatgactcc gtgggaagta attgaaaaaa
    42301 gattgagatt ggctgctgaa gccgattttg taatttgttt gtataatcca agaagtaagg
    42361 gaagaagtga acatctaagc aaagcattca aaataatggg tgagtttaaa ggtggagata
    42421 cacctgttgg agtggtaaaa gatgtaggta gagaaaaaga agaaaagttt gtatgtactt
    42481 ttgaaaatat ggactttgaa aaagtcgata tgactacaat ggttataata ggaaataagt
    42541 ctacctatat taatggtgaa ttgatgataa ctccaagagg ttatacagta tgattttaat
    42601 tttaggagga acttcagata gtttatctat atgtgataag ataaatgaac tgaaaaatca
    42661 accatatatc ctttcagtta ctacagatta tggaagggaa cttgcacaac aacatgcaga
    42721 gaatgtaatt ttaggtaagc ttggaaaaga agatatgcta aaatttataa aagataataa
    42781 tatagtaaaa ataatagatg ccactcatcc ttatgcagtt gaagtatcca aaactgctat
    42841 tacttgtgca aaactattga atatagatta tataaggttt gagagaaaat ctttaattga
    42901 agaaatagat tatgataata aatttatagt agatacaatt gaagaagcct gtgaaatagc
    42961 aaataaaata gggacaaata tattcatagg aacaggaagt aaaaatttga acagatttat
    43021 agaggaaata agtgataaaa atttagttgt tagagttctt ccaacgagtg aagtcatatt
    43081 aagttgtgaa aaattaggtt taagtgcaga taatatagta gctatgaaag gtccatttag
    43141 ccagtatata aatgaagaaa catataaaca ttacaatata gatttagtca taacaaaaga
    43201 aagtggaata gctggtgggt tcttagagaa ggtaaatgca tgtaaaactt tcaatatacc
    43261 agtaataatt ataaaaagag aatcgattaa ctacgaaaat gtatttaatg acataaataa
    43321 aattaaagac atacttgtgt aatttttagg aggagaatat atgaagaaag ccttattagt
    43381 agtgagtttt ggtacaagct atcatgaaac gagagaaaag acaatagata tatgtgaaga
    43441 taaaataaaa aattcgttaa aaagccatga tttttttaga gcttatacat caaatatgat
    43501 aataaataaa ataaaaaaaa gggatggaat agaaatagat aatccaatac aggctttaga
    43561 taaaatatat gaacaaggat atgatgaagt aataatccaa acacttcata ttatatgtgg
    43621 cgaagaattt aacaaattaa aagaacaagt agatggatat tcttctaaat tcaaaaagat
    43681 tgtattagga agacctttgc ttacacatat tgaagattat caggaagctg tagaggcaat
    43741 taagcatcaa attcctcata tggaaagtaa tgaagcagta gtatttatgg gacatggaac
    43801 acttcatgaa tcacattcag cgtatccagc attggaatac atgcttaggg ataatggaat
    43861 aaatgcttat gttggtacag ttgaagggta tccagaaata gaacatgtaa taagaagatt
    43921 aaaagaagga aatataaaaa ctgtaaattt gatgccattt atgttagttg caggagacca
    43981 tgctataaat gatatggcag gagatgaaga agattcttgg aaaacaatat tagaagaaaa
    44041 tggatttaac gtaagagttc atttaaaagg actaggagaa aattcttata tacaagataa
    44101 atttgttcgt catgctgtaa aatgtgcaga gaatgcgaag ttctatggta taggagcagg
    44161 gccaggagat ggttctttac ttacgataaa agcggttaat actttaaaga aactggatat
    44221 tctatacact ccagaatcaa aaaagggtgg agatagtcta gctttatcaa tagttagtga
    44281 atatttacct gaatcagtgg aaataaagtc taggcatttc ccaatgagtt ttgatgggaa
    44341 tgaaaaaagt ttagcttggg acaatgtggc acaagaaatt atatcagatg ttaatgatgg
    44401 taaaaatgta ggatttgtta cattaggaga ccctatgatt tatagtacat atgtatatat
    44461 aatgaaaaga atattaggag aggtagaagt cgaaactata ccaggaattt catcattttc
    44521 caatatagca tctaatcaga attttccatt agtcatggat aaagaagctt tagtggtaat
    44581 tccttgtact atggaagatg ataagataga gtatgctttg caaaattata attcaatagt
    44641 attgatgaaa gtatataaaa attttaaaga aataataaaa aaattagaaa agtatgattt
    44701 aatagaacat gctattttag taagtaattc ttcccaagaa agcgaaaatg tgtttacaga
    44761 tttaaaagaa gcgcaccttg aagataagat atcttatttt tctactatac tagtaaataa
    44821 agataataaa ataaaatagg tgaaagcaat atttaaagga gacttaatat gaatatagtg
    44881 gttggaacta ggggtagtaa tctagcgctt atacaaacag aatgggtaat aaatgaatta
    44941 aaaaagaagt atccagaaat tagttttgag attaaaatca taaagacaaa aggagattta
    45001 attcaaaatg tttcactgga taaaataggt gataaaggat tgtttgtcaa agaaatagag
    45061 caacaattat tagatggaaa aatagacata gcagtacata gtatgaaaga tatgccttct
    45121 tatttagcag atggactaaa atttgctcat acgcctaaga gagaagaccc aagagatgtt
    45181 ctaatactta gagaaggata taaaaattta gatgatttgc ctcatggagc agtaatagga
    45241 acaggaagta aaagaaggaa gtttcaatta ttgaaacaaa gacctgattt aaatatagta
    45301 caagttagag gtaatgtgga aactaggata cgaaaaataa aagatgaaaa catgcatggt
    45361 attgtgttgg cagcatcagg aataattaga gctaatttac aagataaaat aagttcttat
    45421 ttacctgttg atgttgttat tccagcacct gcccaaggag ctttagctat agaaattaga
    45481 agcaatgata gtacgataga gggaatagta aattcactga aggatgagaa tacagaaatc
    45541 caaatattgg ctgaaagagg ttttttagat ggtgtaaatg gaagttgtca tattccaatg
    45601 gcagcttatt gtgaaataat ccaagataaa atacatctta ctggcttata tggagattca
    45661 gaaggaaaaa aagtagtaat caagtctata gatggagata tttcttctcc tagagagtta
    45721 ggtttaaagt tagctaaact tgtattgaag gagtatgaga attatgaagg gtaaggttta
    45781 cttagtaggg gcaggaccag gtgattataa actcatgact ttaaaaggtt tagagtgtat
    45841 aagaaaatcg gatgtaatag tatatgatag attagcaaat agtagttatt taagagaagc
    45901 taagcctgat tgtgaactta tatatgtagg caaggcatca agtaatcata ttttgccaca
    45961 agaagatata aatagaatta tagcagaaaa agctaaagaa ggaaaaattg taactcgtct
    46021 taaaggagga gacccttatg tatttggcag agggggagaa gaagcagaga ctttagtaga
    46081 tgaaggtata gaatttgaag tagttccagg tataacttct gctataggag gtttatgtta
    46141 tgcgggtatt cctataacac atagagacca tgcttcgtca tttcatgtaa taacaggtca
    46201 tttgaagggt gatgatagtg gagaattaaa ctggaatgct cttgcaaata acaaaggtac
    46261 tcttgtgttt ttgatgggaa tttcaaacct agagaaaata agtgaaaact taatgaaaga
    46321 aggaaaagat aaggatacac ctgttgctct tataagttgg gcaactagat ataatcaaag
    46381 agttgttaca tctacacttg aaaatgttta tgaaactgct attaaagaag aagtaaaacc
    46441 gccaactctt atagtagttg ggagtgttgt aggacttaga gaaaagttga acttctttga
    46501 aagtaagcct ttatttggaa aaagtattgc tgtaactagg tctagaaatc aaaatagtgt
    46561 attggtagaa aaaataatgg atttaggtgg aaatcctata gaaataccta ctattaaggt
    46621 agaaaaaata caaaataata ttaacttaga aaatgaaata aaaaatataa ataagtataa
    46681 ttatctaata ctaactagta aaaatgccgt agaaatcttc tttgaaaaga tatatgaaat
    46741 gaattttgat ttaaggatat tatctaattt aaaggtatgt gctataggtt ctgctacatc
    46801 aaatgagttg aaaaaaagag gaattatagc ggatatagta ccaaaaaaat ttgtagcaga
    46861 gtcactgtat gaagagttag cgcctatttt aaatgatgac gataatatac ttatacctag
    46921 agcagaaaat gctagagatt atctggttga caaactcaag gctatttgtg aagtaacaga
    46981 agtacatata tatagaacag taatagatga ggagaaaaaa ggtgagatat tagatatttt
    47041 aaattctaat gacatagatt atataacatt tactagttcc tcaacagtaa ataatcttgt
    47101 tgaaattata ggaaaagaaa atattaaaat attagaaaaa ataaaaacac tatctatagg
    47161 tcctataact acagagacaa taaatagttt gggaataaaa ttgtacaaag aatctgctac
    47221 atctactata gattcgttag tagatttaat tataaaaaat taattttgga ggcttgaata
    47281 tgttaagaag accaagaaga ctaagagcaa gtaaagcaat cagaaatttg gtaagagaaa
    47341 ctaaggtgaa tgtagaagac ttaatatatc cactgtttgt agtagagggg gaaaatataa
    47401 aagaagaaat taaatcttta ccagatgtct atcatttatc aatagatatg ctagaagacg
    47461 aaataaaaga aataagtgag ttgggaattg aacatataat gttatttggt gttccagatg
    47521 aaaaagatga gtgtgcttca caagctttta atgataatgg aatagttcaa aaggcaatta
    47581 gaaaggtaaa agaaataaat tcagatataa atgtaataac agatgtctgt atgtgccaat
    47641 atacaagtca tggacattgt gggattttaa ctgatactgg ttatgttgat aatgataaat
    47701 cattggagta tttggctaaa atatctgtaa gccatgctaa agcaggagct gatatggttg
    47761 ctccatctga tatgatggat ggaagaatac aagcaataag agaagcttta gatgaaaatg
    47821 gattagaaaa tgttggaatc atggcttata gtgttaagta tgcttcaaat tattatggac
    47881 cttttagaga ggcagctcat tcagcaccat cttttggaga tagaaaaaca tatcaaatgg
    47941 acccagcaaa tagcaatgaa gctataatag agactgaact tgatatattg gaaggtgcag
    48001 atatacttat ggttaaacct gcattatcat atttagatat tataagaaga gttaaagata
    48061 attttgactt acctctagca gcttataatg taagtggaga atactctatg cttaagtttg
    48121 ctgtgaagga aggtttatta aatgaagatg taattcttga atcaattaca tctataaaaa
    48181 gagcaggagc agatataata ataacttatt ttgctaaaga cattgctaaa ctgttgaaaa
    48241 aataaattct agcagtataa agaatatcaa aaagtatagg aattgtaatt aactattata
    48301 cagtagtttt gtttagacat ttattgaaga ataatagaaa ctaatttgca atttctatac
    48361 tttatttatg taactaaata aaatttggag gtagaagatg ctatatccta ttaatttaaa
    48421 attagatgag ttagatgtag ttataattgg tggtggagaa gttgcatata ggaaatgtaa
    48481 aaatttttta gagtttaaca aaaatgttac tatagtttct aaacaaattt taaataaatt
    48541 ttatgattta aaaggaaata taaaaataat aaaagatgat tataaagaaa tatatataaa
    48601 agatgcttct gtaataattg ctgccacaaa taatagagag ttaaatatgg aaataggatt
    48661 atattgtaaa gcaaaaaata agctagtgaa tgtagttgat aatatagaaa tatcgaactt
    48721 tactgttcca tcatatataa aaagaggaga tttacttata agtgtgtcta ctgggggcaa
    48781 gagtccttca ttatcatcaa agataaaaaa agaaattgaa gagagatata ctgaagatta
    48841 tgaggagtat ttaaatgtat taggagatat aagaaaaaag gttataaaaa aatacgaaga
    48901 taaaagtaaa agaaaagatg tgcttaatat gttggtaaca cttgacctag aagaacttaa
    48961 gaagtttgat atataaaaaa taaaataaaa aatgttaaaa aggtgttgac ggattatttt
    49021 taag
//
LOCUS       DAYAKB010000025        48829 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.025, whole genome shotgun sequence.
ACCESSION   DAYAKB010000025 DAYAKB010000000
VERSION     DAYAKB010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.025"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            179..1546
                     /locus_tag="ACGI3L_001697"
     CDS             179..1546
                     /locus_tag="ACGI3L_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFG9197409.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            1571..2179
                     /locus_tag="ACGI3L_001698"
     CDS             1571..2179
                     /locus_tag="ACGI3L_001698"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HFG9197410.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            2227..2598
                     /locus_tag="ACGI3L_001699"
     CDS             2227..2598
                     /locus_tag="ACGI3L_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFG9197411.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            2777..3115
                     /locus_tag="ACGI3L_001700"
     CDS             2777..3115
                     /locus_tag="ACGI3L_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFG9197412.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            3581..4084
                     /locus_tag="ACGI3L_001701"
     CDS             3581..4084
                     /locus_tag="ACGI3L_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HFG9197413.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGVYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            4131..5090
                     /gene="moaA"
                     /locus_tag="ACGI3L_001702"
     CDS             4131..5090
                     /gene="moaA"
                     /locus_tag="ACGI3L_001702"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HFG9197414.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            5094..5564
                     /gene="moaC"
                     /locus_tag="ACGI3L_001703"
     CDS             5094..5564
                     /gene="moaC"
                     /locus_tag="ACGI3L_001703"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061799 - cyclic pyranopterin
                     monophosphate synthase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HFG9197415.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            5600..6031
                     /locus_tag="ACGI3L_001704"
     CDS             5600..6031
                     /locus_tag="ACGI3L_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HFG9197416.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
     misc_binding    6462..6673
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6836..8125
                     /locus_tag="ACGI3L_001705"
     CDS             6836..8125
                     /locus_tag="ACGI3L_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HFG9197417.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            8179..9258
                     /locus_tag="ACGI3L_001706"
     CDS             8179..9258
                     /locus_tag="ACGI3L_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HFG9197418.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            9279..10823
                     /locus_tag="ACGI3L_001707"
     CDS             9279..10823
                     /locus_tag="ACGI3L_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase N-terminal
                     domain-containing protein"
                     /protein_id="HFG9197419.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(10986..11528)
                     /locus_tag="ACGI3L_001708"
     CDS             complement(10986..11528)
                     /locus_tag="ACGI3L_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HFG9197420.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(11676..11960)
                     /locus_tag="ACGI3L_001709"
     CDS             complement(11676..11960)
                     /locus_tag="ACGI3L_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFG9197421.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(12023..12787)
                     /locus_tag="ACGI3L_001710"
     CDS             complement(12023..12787)
                     /locus_tag="ACGI3L_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFG9197422.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(13069..13335)
                     /locus_tag="ACGI3L_001711"
     CDS             complement(13069..13335)
                     /locus_tag="ACGI3L_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HFG9197423.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(13377..14186)
                     /locus_tag="ACGI3L_001712"
     CDS             complement(13377..14186)
                     /locus_tag="ACGI3L_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197424.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            14499..14780
                     /locus_tag="ACGI3L_001713"
     CDS             14499..14780
                     /locus_tag="ACGI3L_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197425.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            15044..15298
                     /locus_tag="ACGI3L_001714"
     CDS             15044..15298
                     /locus_tag="ACGI3L_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197426.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            15343..15666
                     /locus_tag="ACGI3L_001715"
     CDS             15343..15666
                     /locus_tag="ACGI3L_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HFG9197427.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(16225..16419)
                     /locus_tag="ACGI3L_001716"
     CDS             complement(16225..16419)
                     /locus_tag="ACGI3L_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9197428.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(16793..18412)
                     /locus_tag="ACGI3L_001717"
     CDS             complement(16793..18412)
                     /locus_tag="ACGI3L_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFG9197429.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            complement(18721..18939)
                     /locus_tag="ACGI3L_001718"
     CDS             complement(18721..18939)
                     /locus_tag="ACGI3L_001718"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197430.1"
                     /translation="MFFSLFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSILDVAVLI
                     GFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            19232..19423
                     /locus_tag="ACGI3L_001719"
     CDS             19232..19423
                     /locus_tag="ACGI3L_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197431.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(19512..20324)
                     /locus_tag="ACGI3L_001720"
     CDS             complement(19512..20324)
                     /locus_tag="ACGI3L_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HFG9197432.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            20746..21897
                     /locus_tag="ACGI3L_001721"
     CDS             20746..21897
                     /locus_tag="ACGI3L_001721"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9197433.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVISDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            22015..22653
                     /locus_tag="ACGI3L_001722"
     CDS             22015..22653
                     /locus_tag="ACGI3L_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HFG9197434.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            22654..23676
                     /locus_tag="ACGI3L_001723"
     CDS             22654..23676
                     /locus_tag="ACGI3L_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HFG9197435.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            23666..24286
                     /locus_tag="ACGI3L_001724"
     CDS             23666..24286
                     /locus_tag="ACGI3L_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197436.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(24410..25096)
                     /locus_tag="ACGI3L_001725"
     CDS             complement(24410..25096)
                     /locus_tag="ACGI3L_001725"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFG9197437.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQNKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(25110..25655)
                     /locus_tag="ACGI3L_001726"
     CDS             complement(25110..25655)
                     /locus_tag="ACGI3L_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197438.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            25883..27130
                     /locus_tag="ACGI3L_001727"
     CDS             25883..27130
                     /locus_tag="ACGI3L_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFG9197439.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLTFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            27217..29211
                     /locus_tag="ACGI3L_001728"
     CDS             27217..29211
                     /locus_tag="ACGI3L_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9197440.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            29211..30533
                     /locus_tag="ACGI3L_001729"
     CDS             29211..30533
                     /locus_tag="ACGI3L_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HFG9197441.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            30812..32098
                     /gene="grdG"
                     /locus_tag="ACGI3L_001730"
     CDS             30812..32098
                     /gene="grdG"
                     /locus_tag="ACGI3L_001730"
                     /EC_number="1.21.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     alpha"
                     /protein_id="HFG9197442.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            32184..33491
                     /gene="grdF"
                     /locus_tag="ACGI3L_001731"
     CDS             32184..33491
                     /gene="grdF"
                     /locus_tag="ACGI3L_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_082007859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:33231..33233,aa:Sec)
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     beta"
                     /protein_id="HFG9197443.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            33783..34499
                     /locus_tag="ACGI3L_001732"
     CDS             33783..34499
                     /locus_tag="ACGI3L_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9197444.1"
                     /translation="MYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVE
                     DLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAFEVDAI
                     NYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIY
                     VHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVS
                     RLRQQIFSKVMLEFMKNRRI"
     gene            34501..35859
                     /locus_tag="ACGI3L_001733"
     CDS             34501..35859
                     /locus_tag="ACGI3L_001733"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9197445.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            35949..36383
                     /locus_tag="ACGI3L_001734"
     CDS             35949..36383
                     /locus_tag="ACGI3L_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197446.1"
                     /translation="MKVGNINGQAPITNGLDSCQSEVQGLEQKKKALQDEIEKVRSDK
                     SIDGETAKLKIEALKKEMEEIENKIQELKGNKGKKTNKEENNVSEVNNNLLERKKEPS
                     NNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRPI"
     gene            complement(37038..37262)
                     /locus_tag="ACGI3L_001735"
     CDS             complement(37038..37262)
                     /locus_tag="ACGI3L_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9197447.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(37359..38612)
                     /locus_tag="ACGI3L_001736"
     CDS             complement(37359..38612)
                     /locus_tag="ACGI3L_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HFG9197448.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            38872..39861
                     /gene="add"
                     /locus_tag="ACGI3L_001737"
     CDS             38872..39861
                     /gene="add"
                     /locus_tag="ACGI3L_001737"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFG9197449.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            39933..40673
                     /locus_tag="ACGI3L_001738"
     CDS             39933..40673
                     /locus_tag="ACGI3L_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HFG9197450.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPSLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            40873..42024
                     /locus_tag="ACGI3L_001739"
     CDS             40873..42024
                     /locus_tag="ACGI3L_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="double-cubane-cluster-containing anaerobic
                     reductase"
                     /protein_id="HFG9197451.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            42049..42804
                     /locus_tag="ACGI3L_001740"
     CDS             42049..42804
                     /locus_tag="ACGI3L_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008047 - enzyme activator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase"
                     /protein_id="HFG9197452.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            42996..45383
                     /locus_tag="ACGI3L_001741"
     CDS             42996..45383
                     /locus_tag="ACGI3L_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HFG9197453.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(45614..45847)
                     /locus_tag="ACGI3L_001742"
     CDS             complement(45614..45847)
                     /locus_tag="ACGI3L_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFG9197454.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            46136..46726
                     /locus_tag="ACGI3L_001743"
     CDS             46136..46726
                     /locus_tag="ACGI3L_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9197455.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            46840..47685
                     /locus_tag="ACGI3L_001744"
     CDS             46840..47685
                     /locus_tag="ACGI3L_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197456.1"
                     /translation="MIKVDDLSFSYTERDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            47682..48365
                     /locus_tag="ACGI3L_001745"
     CDS             47682..48365
                     /locus_tag="ACGI3L_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197457.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            48362..>48829
                     /locus_tag="ACGI3L_001746"
     CDS             48362..>48829
                     /locus_tag="ACGI3L_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197458.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILV"
BASE COUNT        19161 a         5190 c         7909 g        16569 t
ORIGIN      
        1 gtaaaaaaat taaaattaaa agtaaaaaac taaataaatt aatgttaatt tgaaatatat
       61 atgaaggttt ttggagaata cttacttatg ataggaaaaa atgttaaaat aatagtgtaa
      121 tcaaatataa aggactgaaa taattaacag ttattaaata ttaggagtgt aaaaatttat
      181 gggattaaaa gaatttgatt ttattgaaga gtctattgat atgttgagga caatgtcacc
      241 aacattagaa actatatcag atgaaataga agaatatttt gaaaatatct tggatgaaaa
      301 gaatcaagaa tatataaatg taacctctag aataaaatca gaatcaagtt taagagaaaa
      361 gataattaga aatagatatt taaaaaaata tggagaagca agtaatctta ttcataatgt
      421 ttctgactta ataggcctaa gaattgagtg tagatttatt gaggatgaaa acaaaatata
      481 tagacttttg agaagatatt ttaataaaac agatgacaaa ataaactatt ataataaaga
      541 gaataagaat attaaattaa aactatctga gaggcaaccc aataagcaaa aaaatggatt
      601 tgaaatatat aaaatagatg gagtttttgc gtatttagat agagaagtaa aatttgaact
      661 tcaaattaaa tctcttgtaa atgtgttttg gagtgaaata gaacataaaa taatttataa
      721 aaacaataca tatttacttg ctgataaatt tataaaggat atgatggact ctataaagaa
      781 taatcttact atgatagata atcagctttt aagtatttat aaaaactttc attcagggaa
      841 gtcttttaat atgaaagtaa gtaaaaaaga aattgaaaaa ttatttgcga aactagtcta
      901 tgacgctttt tctgaaaaga tgaataaaag tataggtttt gttgtagatt ttaaaaaacc
      961 atgtgagact atattgaact attcttttaa taaacaagat ataagtgatg aagttttagg
     1021 taattttatg cttgatgagt ttgcaagatt aaatgaaatt gtaaacaagg atatagattt
     1081 taatgagcaa atagaatttg aaagagaacc aacatttgat gataagtttt gtaaagacct
     1141 aggaaatcat tttagaagta gattaaacac agaatttcca tggaacctat tttttagaat
     1201 attatttgaa atagagccat ataacaatac caaagacttt gaaaactttg tagagtttat
     1261 aaaagaaaat gtgctactag aagaaaatag ggagcaatta ttatgccaat ttgaagagga
     1321 tagtaagctt ataattgaag atatatatga ttgtatattt aatagtataa gtgagattga
     1381 tagtgttgaa attttatata actataatct tgaaaaaata aactttacat caagtgaaat
     1441 cataaattgt atatgtagag aatatgagtg ttatggtgaa tacttagaag aaaaagaaaa
     1501 gcttatgaat acatttaaag aaaagattat tcaaatcttt gagtaatagg tcaatgctga
     1561 agtggcgcta atgcgccatt tttcaaatat atatgaatta agtaaaatta ttttggagga
     1621 ggcgatttgt atagagaaaa caggtgtaat tttggcaggg ggaaaaaatt ctagaatggg
     1681 tagagataaa gcctttttag agttacatga taagcttttt attgaaattg caatagaagc
     1741 atttaaaaac tttgatgagt tgataataat atctaacaat gaagaattat attctaaata
     1801 cgatattaaa gtttataatg atatagtaaa agatgttggt ccaattggag gaatatatac
     1861 tgctcttgaa tatgcaaagt atgatatagt tacaattgca tgtgatatgc catatctaaa
     1921 taatcaaata gtcgaaagaa tagctaataa aatggatgat aaaagtgtga tttcagtgac
     1981 aaatggaaag ttacaaccat tgtgttctgg atataaaaag agtataataa ataaagtatc
     2041 tttatgtata agggaaaatg atttaaagct cagaagcttt atagataaaa tagataaaag
     2101 ttatatatac tttgatgaag aagatttatt tttaaatgta aacactgttg atgagtataa
     2161 aaaattaact aaagtttaat tagctatggt tgtaaaatag agtaggattt atatggagga
     2221 gagtttatga atttacttaa atgcgattct tgggcagtaa tattaaataa tagcgataaa
     2281 gaaagtaaag catataaaat attagatgaa cttaaaagga atatgtacaa agttgttgct
     2341 atagatgaag agaaaaaacc tattgaagga atagatgtgt atgaatgttt aaaagatgtt
     2401 ccacacaata ttgatgttgt agctattatt gataaacaat ctaagatgga tgtgatttta
     2461 gaagaagtag agcttttgga tatacaaaat atgtggtttg aaaaaggaag ctttagtgaa
     2521 atgatgatta aaaagactaa agatttaaaa ttaaatatag aatataattt aagtttatat
     2581 gatgagttga ctagataaaa ttatatttct taataataaa aatataatta gttaataaaa
     2641 catattattt tatagtatag attggttaat aaaagtacag attggttaat gaaacattaa
     2701 attacaatat ttgttaaaaa aattgtgagt tacatgatat aatgtattaa ataggatact
     2761 aaggagttga tatattatgt taatagtaac tacagaaaaa gtagaaggta aaaagatatc
     2821 aaaggtttta ggattagtga gaggaagtac aataagagca aaacatgttg gaaaagatat
     2881 aggagcaagt tttaagaatc ttgttggagg agaacttact ggatataatg aaatgctcac
     2941 tgaagcaaga caaattgcca taggtagaat ggttgaagat gcagaagcta aaggtgcaaa
     3001 cgcagtaata gcatttagac tgtcttcagc ttcagttatg caaggagcag cagaaatgct
     3061 tgcttatgga acagcagttg ttttagaaga tgataatagt attcttgaaa aataaaatat
     3121 aaatagttaa aaagaggcat cttttaaaaa ttttatggat gccttttttt atttgaaaaa
     3181 actaatttga gaagaaattt taactattat gacaataaaa ttagggtgat attatataaa
     3241 taagtaaaat tatattatat aatgtatggt atagacttta aaaattttat ttgtagagaa
     3301 aaatatggac aatgttataa taattataga aattaaaagt acttacattc attatgtatg
     3361 tgacatgtat aattagtttt atatttaata cagttttgaa gtaatatctt cattttgaga
     3421 acgttggaat aataaaaaat gtattattat aggtgatata aataaaaaat aaatataata
     3481 tgttatattg ctgatagaaa agagaataaa agaaaatagg ttttattaaa agagattttt
     3541 atttatagga cttaatcaat gtatagaggg gtgagaacat atgtttaatg ttgcaattat
     3601 aacacttagt gataaaggat atgaaggaaa aagagaagat ataacaggaa aaaagttaac
     3661 tgaatttgtt gaaaatacag gagtttataa agttactgaa tatgtactta taaaagatga
     3721 taaggaaatg ctaaaggaaa atattataag actttgtaat agtaataaaa tagatttaat
     3781 tcttacaaat ggaggtactg gtttttcaaa aagagatata accccagaag caactaagga
     3841 agtgttggaa aaagaaatac caggtctgag cgaatatatg agaatgaaat ccacagaaat
     3901 tactaaaaag gccatactaa gtaggggtgt gagtggaata agaaataatt ctataataat
     3961 aaatttacct ggaagtccta aaggtgcagt tgaaaatcta agttttataa ttgatgtttt
     4021 agaccatggc atagaagttt taagaggaga agctacagaa tgtgccacta aaaaaagtga
     4081 atagtatata atctagatag ataaaaaata gacaaagagg tagataaagt atgattgata
     4141 agtatggaag aaaaatagac taccttcgta tttcacttac agataagtgt aatttaaggt
     4201 gtgtctattg tatgccacca gatgtaaaat ttgataaaaa ttatataaat gaaaatctaa
     4261 gctttgaaga ctacaagttt attataaagg ctatggctga acaaggtata acaaaaatta
     4321 gatttactgg aggagaacct cttttatatc ctaaattaaa tgagcttata aaatttacaa
     4381 aagaagaatg tggaataaat aacataggaa tgaccactaa tgctattggt ctttctgata
     4441 gaatttttga gcttgaaaaa tgtggcttaa ataaagttaa tataagttta gattctttga
     4501 aggaatataa gtataaatcc ataacaagag gaggaaactt aaaagatgtc ttaaaatcga
     4561 ttgaatcttg tttaaattta ggtataaaag taaagttaaa ttgcgttgct ataagtgggt
     4621 ttaatgatga tgagcttaaa gattttatgt ttttaacagt taaatcacca attgatgtaa
     4681 gatttataga gcttatgcca ttaggtgagg ctaatagagt ttataagaag ggttatttta
     4741 atgtaaaaga aatgattgaa aaaatatatg gtttatataa agtcaaaaat gatgaaaaaa
     4801 gtacagcaga atattatatg tttaaaggag ctaaaggaag aataggaatt ataactccat
     4861 taagctgttc attttgtaac acttgtaatc gtattagact tacttctagt ggtgcaataa
     4921 aattatgtct acattcaaaa gaagaaatag atataaaacc atttttacat aaaccattgt
     4981 tatttagaga atctatgaaa gatataataa aacaaaaacc agaaaaacat catttaatag
     5041 aaaataaatg tagtgataca aataggcgta tgtatgaaat tggaggataa gtaatgttaa
     5101 cacatataaa tgaaaaaggg tatgccaaga tggtggacat aagtgaaaaa gatgatacta
     5161 aaagaacggc cgtagctaca gctacaatta ctcttagtaa ggaagcatta gaaaaagtaa
     5221 aaaatggtca gataaaaaaa ggagacgtat tgtctgtagc tcaagttgca ggtataatgg
     5281 gagctaaaaa tacatcttca aacataccaa tgtgccatca gattaaatta gttggatgtg
     5341 atttagaatt tgatgtagat gattctatgt ctgctattaa gatatacgca acctgtaaat
     5401 ctcttgggaa aactggagta gaaatggaag ctttaaatgc atgttcttta gcagcactta
     5461 caatttatga tatgtgtaaa gcagttgata aaaaaatggt tataagtaat atccatcttg
     5521 tggagaagac tggtggaaaa tcaggagatt ttaagttcga gtaaattaat aatatattgg
     5581 gttaaaattt ggaggaaata tggcgaaggt agtgtcaata aatataagtg agaaaaaggg
     5641 tgtaattaaa gttcctgtac aatgtgcaga gctaaaaata aatcatggga tagttggaga
     5701 tgcacatgca ggaaactggc atcgtcagat aagcttactt ggaaaagaaa gcatagataa
     5761 aatgaaaatg aaaggctttg accaattaaa atatggagat tttgctgaaa atgtaactac
     5821 agaagggata gaagtttttt ccctgcctgt tggtacaaag ttaagaatag ggcaatgtga
     5881 agttgaagta actcaaatag ggaaaaaatg tcacaatgga tgtgaaatta agaaattgac
     5941 aggtgactgt gtgatgccac gagaaggaat ttttgtaaag gttctaaaag aaggaattat
     6001 aaatgtgaat gattcaatag atgtaatcta atgaagtcac tattaaaata taattataag
     6061 taaatactat taagatttaa atatatattt taagagagaa ttaattttaa taaaatattt
     6121 tagttataaa ttggaatatt ggttatataa agctatgaat gtaaaatcat agctttttgt
     6181 ttttgaattt taaaatataa tattttattt atatatatta aattatattt tatataaaat
     6241 caattgttta aatatatatt atttatactg taaatttata gataataaag tataaaaaaa
     6301 atatattttg atgaaattta aaaaaataca ttatataaat atagtaatag tatgaaaatt
     6361 tacatataaa actaaaaaat gcaagtaatt gactttttaa gttgacaaaa tattgcatat
     6421 atattatgat ataaatcata aattaactac aaatcaatat tatatattcg tagaagaaga
     6481 aagtagcata aaggaatttt acagagagtt agatttggct gagaactaat attggaattt
     6541 atgtgaaaag gactttggag aatactattg taattatgtt agaatagtgg tttaattcgc
     6601 cttaagaaaa tgagtgagta aaattaattt ttactaataa gagtggtaac acggatttat
     6661 attcgtctct tggatttttc caagaggcgt tttttattat aaacttattt cagaaaattt
     6721 aaaactatat attaaatgaa aattataaaa atatgatagt taataaattt ataaattaga
     6781 aaattgtaaa atatgctaag gtcagtagtt ttacgattta aatggaggga tgaaaatgga
     6841 agaagaaaaa attaactatg ctctggaaca gattccagag aatcaaaaac gtggttgggt
     6901 agctatgttt tcagttttag tagcaatagg tgtggattta tcatctgtta ttttaggcgc
     6961 tgagttggca cagagtatgc caatgaaaca agcaatattg tcagtaattg ttggttcatt
     7021 tttttctgca attttgtata ctacatgctc tttggttggt tcatctacaa gtttatctac
     7081 atctatgata acaaagtatg tatttggaga agctggagca aaaatatttt ctctagttat
     7141 aggggtttct ctattaggtt ggtttggagt tcaagtaggt ttctttgctc aaaatgcaca
     7201 gataataata aaagatatat ttaatttaga tgtcagtatg cagattttaa gcctaatagg
     7261 tggtctcttg atgatgagta ctgcaattta tggatataag gcaatggaga agttgagtgt
     7321 gtattcagta ccatttttat tagttcttat gatgctaact atattcttag cttttagagc
     7381 aaatggaatt tcagttgatg ataatatgaa atctactatg acatttgcag gtggagtttc
     7441 tctgtcaatg agtataataa tagttggtgc aattgtatct cctgatataa gtcgttgggc
     7501 taaaagtaga agagactgtg ctctttcaag ctttttggga atacaatttg gaaatgcttt
     7561 tatgataata gtttcgatag tattagtaaa atgtatggga acttcagata ttatgagaat
     7621 ttttattaca ttaggaattg ctataccagg tataatagta cttacattag cacaatggac
     7681 tacaaataca agtaatgtat attcagcatc attaagtata gctcttgtac ttaagaaggc
     7741 tcctgagaaa gtattaacta tagtccttgg tattatagca acattattgg ctgtatttgg
     7801 aatatatgaa ggttttatag gatttttaaa tttacttgga attgtaattg cacctgttgg
     7861 tggtgtatat acagcagaat attacatagt aaagcaagaa cttaaaggct ttgataaagg
     7921 agtattatat aaaccaatag ttaaacgttc aatagtgtct tggataattg gtatattaat
     7981 aacttacctt tcaacatatg gatttataac tcttactact atagcacctt tagatggttt
     8041 tatagcaggg tttgtagtac aatctattat tggaaaagtg ctttgttcaa caaaaaataa
     8101 gcaagaaata gacaaagcag tataaagaaa tttgtttata aagtataaaa taaattagaa
     8161 atatgaggag aaagtaacat gagattttta acagaagaaa gtgtagataa aatagcagtt
     8221 ggtgcagcag tgcttggaac tggaggtgga ggtgacccat atgtaggtaa attggttgca
     8281 aaacaagcca ttaaaaagta tggtcctgta aaagtaataa gtttagatga acttgatgat
     8341 gatgctttgg tagttccagt atctggtatg ggttctcctg taattacaat agaaaaatta
     8401 ctttcagaag tagagttaac taccccttta gaaataatgg agaaattatt aaatagaaaa
     8461 gtggatgtta taattcctat agaaatagga gggataaact cacttatgcc tatagcagtt
     8521 gctgctaaaa aaggacttcc tatcttagat gcagattcta tgggtagagc tttccctgaa
     8581 gctcaaatgg taacttttta tcttgaagga tatgaggcat ctcctgccgt aatgtctgat
     8641 gaaaaaggta attctgccat cctttatcct gtggatggaa tttggtcaga aagattagct
     8701 agaactttaa ctgtagaaat gggaggaagt tcttctatta gtgactataa tttaagtgga
     8761 gctcaagtta aaaaagctgc tataggtaat actcttacaa tagctgaaac tataggaggg
     8821 tttttacttg aaaataaatc tgattcaaaa ggtgctgttg agaatatact aaaagaattg
     8881 tgtggataca agttatttga aggaaaagta attgatatta agagagagtt gaaaggtgga
     8941 tttactagag gacatgcctt ttttgctggg attaatgagt atgatggaga gtattctata
     9001 ttattccaaa atgagaattt aattgccaaa aaaggtgata caccactttg tattacacca
     9061 gatttaatag cagtattaga tttagaaact ggatttccaa taactacaga gagaataaaa
     9121 tatggctctc gtgttatggt agtagctttt ccttgtaatg aaaaatggag aacagaaaaa
     9181 ggaattgaga cagttggacc tggatacttt ggatatgatg tggaatataa aacagtagaa
     9241 gaattacaag gaaaataaaa gtttaggagg aaattttgat gtatcgtgta ggaattgacg
     9301 ttggaggaac aaatacagat gcttgtatac tggatgggga attaaaagta attcattcag
     9361 ttaaggtggc aactacaaaa gatgttgaaa ctggtgttta caatgcctta aaaaaagtta
     9421 tagatgaaag taagattgac cattcattaa taaaatatgc tatgcttggt acaactcatt
     9481 gtacaaatgc tattgtagaa agaaaaagac ttaataatgt ggctatgata agaataggaa
     9541 agccggccac tactgccatt cttccattta tagattggcc agaagactta agagaaaaaa
     9601 tagaattaga ttcaatattg gtatctggtg gatatgagtt tgatggcaga aaaataaatg
     9661 aactttgtaa agatgaagtt gtagagtttt gcaatagaat aaaaggcaaa gtggaaagtg
     9721 ttgcaataag tggagtattt gctccagtaa ataaacaaca agaagaagaa gttgcaaaat
     9781 gggttagaga aattttaggg gatattccta tatctttatc aaatgaaata ggtaatatag
     9841 gtatattaga aagagaaaat ggagctattt taaattctgc attgtctcaa gtaggtaaag
     9901 ctgtatcttt aggatttgaa aaagcactta aagatttagg tatagatgct caaatatatt
     9961 tcagtcaaaa tgatggaaca ttaatgaatt tagagtatac aatgaaatac ccaattttta
    10021 caattggatg tggaataaca aattctataa gaggagcttc cttcttatca aaagtaaaaa
    10081 atgcaatagt attagatgtt ggtggaacta caagcgactt gggtgtacta tataatggat
    10141 tccctagaga atcatctatt ccagttacaa ttggaggagt acatacaaac tttagaatgc
    10201 cagatgtttt aactattggt cttgctggtg gtacatgtgt aaaaggcgaa aaagataata
    10261 taaagatagg tcctgaaagt gtgggatata gaataactga agatgcaata atatttggtg
    10321 gagacactct aactttatca gatgttgtta caaaattaga tatggcgttt gaagatagaa
    10381 aaagcaatgt tgaaaactta gataaagagt attgtaatga ggtatataag aaggttattt
    10441 taaaattaga agatgctgta gaccaaatga agactagtca agatgatgtt gaattggttt
    10501 taactggtgg aggaagtata attgttcctg aaaaactaaa aggcataagc aatgttataa
    10561 gacctcctca ttatactgct gcaaatgcta ttggtgcagc tttaggacaa ataagtggag
    10621 atgtagaaaa agtatacagt ttagataaaa tgtcgagaga agatgccata gaagatgcaa
    10681 aaaaagaggc tgtaaataaa gctctaaaag ctggtgctaa agaagatact atagaagtat
    10741 taaatataga agatgttcca cttgcatacc ttcctggtaa tgcacttctt ataaaagtaa
    10801 aagttgttgg tgatttaatt taaagaataa atataagtat ttccagaatt atataaatat
    10861 ttctggactc atttttaaac ttattttatc aataaaaaca gcataacttt tgactatatt
    10921 cttataagtt tccgaacagc cgatatatac ctattttttg aggtttatcg gctgtttgtt
    10981 atcttttatc gcattccaac tatttttctt accgtatttg ctgtacgaat tgtaatctta
    11041 tcacttacat ttgaactggc agtctttgac caccaatttg tctttttata atctttacga
    11101 ctaaaagacc aaaagatagc atttttataa tgatatactt tttcatactc ttctttagga
    11161 tttccaacct catcataaaa ctcgtcataa gataagtcag gaaacataaa aataagatta
    11221 tcatatattt ctttgttgtt atctccccac caattaggag cattatttag tatatctttt
    11281 aactcttctt gtgaaataat aaaaactggt atttccaatt caaactgttt ttttatcatt
    11341 aatcttattg tatttgagat aaccttgctg tcatctacat cacttaaaaa gacaacatta
    11401 ccactattaa ggtatgtaga aacttctgaa taaccaagtt ctacaaagct tgcttttaat
    11461 tcagacataa ttatcttgtt cttaccactt atattgatac ctcttaataa tgcgatataa
    11521 cttttcatat aataatttca cctctaaaca ttcacatttt tctatgtagt acaaacttga
    11581 atttgcatct tttataattc tttcaaaact tcttcatatg taattttttt aatataaaaa
    11641 aatcggtgct taatttgtac cgatttttgt ttttcctagt aaagaactcg tttttttgct
    11701 tctgctatag ctctagcagc actttttgct tgcattcttt tttcttcttc ttttttaaat
    11761 tcatttattg tttcatttag attcttatca tgttcatttt tttctttatc ttcgttttct
    11821 ctgtatacta atatataatc tattattgat tcgtttatta tctgagatat acttttattt
    11881 tcattaattc ctattctctt aacttcctta agtagagtct catcaatatg aaccgttgtt
    11941 tgctttgtat tttttgccac cttaatcacc tcttaaaaaa aattctaaca ttaaaatttt
    12001 ttttagtcaa taaattttaa tattaaaatt ctttaaatgt tttatttgat tttctaaaat
    12061 tttctattgt atttatcatc ttatttttta tattttcacc tagtacagaa gactttagtc
    12121 taggattttc gatatggtca taaattggtt ctaaaaattc aacttcgaca ggaacagagt
    12181 taattttacc aataggttgg tatccttcat aagtatcttt tgaatttttt attacgagtg
    12241 gaacaatagg gcattttgct ttatatgcta tctttaaagc tccacttcta aactccgaaa
    12301 ccaatgaatt tggttcttta atccatgtta aatctccttc tggaaacact gccatacttt
    12361 gacctgtaag tatattttga gaggcttggg ctatactctt tataccctca cgattgtttt
    12421 ttctgtttac atatacacat cttagtaatt ttgcccattc tttaaatata ggtatatttc
    12481 tccaaactgg ttcatctgca attacacatc caattggtct ttctacactt gctgttagta
    12541 tgaagctgtc aagcatacta gaatgattta caacaaatag aagtggttct tttggcagtg
    12601 tttccttacc aattatatta agctctatat tcactatatc taaagatttt ttagcttgtt
    12661 tttgcataaa ttcaaatttt tcctttaagc taaatttatc aggattcttt ttaattttaa
    12721 taagcctagg tatagaagat gtaaaaccta taagttgata tgtagcaaat tttaagtaat
    12781 tattcataaa attatctcct taaaataaaa ttatttatta ctgtaaagat tttaacataa
    12841 aataaaattt aagtctattt taattcaatt ttgtaacata tattttaaat agacagagat
    12901 tgagatttta tatttccaat tttagtaatc agattttatc aataaattac tattctatta
    12961 atttaattaa ataaccttta aatttaatta taaaaactgt tgcagaaatt tctacaacag
    13021 tttaaaaaat ttaccttaca aaaacttatt ttataacaag agagtatatt ataaggctag
    13081 tacagcccat tttttgcact gagaaattct tttgccatca tcaccttgtt ctttgtcata
    13141 tgcaaattga ttaagcattt cacatggaaa tgtatcacat agaccacaat gtgtaaggtt
    13201 tttatcttca caacaagatt ttacaggaca ttgttcaccc caaaatggtt tctcaatctc
    13261 tgtacaacct ttacaattga ctttttcctt gtatccacat tcataacata aaattccaca
    13321 tcttgattct atcattttaa gtcactcctt aaatataaat tttatatgat tgtatatcaa
    13381 aatttatact tttcattgta aaaatcggac aaatttttta tataggttgt tggattaaca
    13441 ccacaaatag atttaaaatc atttataaaa tgagattggt cgtaataacc aatatcttgt
    13501 gctaaagttg caaatggtat tttattattt tgtatttctt gtaatacaag gtttatacga
    13561 agtaatctaa ggtatgattt aacactcata ccaagagaat tattaaaaat tctatttaaa
    13621 tgtcgttcac tataacaact aatttgtgaa atgtttttaa cagacataat agagttttgt
    13681 tttctagcat tttcaagaat tggtatagtc atatctacta tatttgattt caataagtat
    13741 gataagaata acatatctaa ttgttctact aattccttta tagtacttgt tctttcaaaa
    13801 atggaattaa cctctaagct aaataatgtg ttaaaatctt caagtgaaat ttttaaatct
    13861 gtagattctc tttgagaaag acctgtcaaa taatatactc cacctgggcg aaactcaacg
    13921 aatactctaa aaagtacatt ttctatatca ttttttacaa tagtagtttt tgttgtggct
    13981 ccccagaatg cgctttctat accttttttg tcaaatttaa atatcataca tccactagca
    14041 tcaggtatta atgtaagatt ttctttaata cttgtatctg gaatagatat tgtatagtgt
    14101 gctatatact gtcttaacaa tttatgtggc aaaatatatg tatactgttt gcaggtattt
    14161 aaaatgttat tgattatttt attcataagt atatcctcct gatatataaa aaataagtat
    14221 actaatttat tttttatata ataaaccagt tttgttttaa ttgaaatatt ctaataagat
    14281 attttgttaa atttagatac aataattgta aagtaaaatc tcaaaatata caattattat
    14341 aaatcataga tatttattaa ataaatatat taaagaagaa ggaatataaa acaagattag
    14401 aaaataatag tgttactttc ataataaata catataaaga tatttttaag aataaaattt
    14461 attattaaat aaaaaataaa ggagagtgat ttaatagcat ggcatcaaaa caaataccaa
    14521 gaaacaattt agaaaagttt ttaagaataa gagtcttatc acatacaggc gataaaatac
    14581 atataaagtt acctgtaaat tttgcaaaga gaatgattga gaataatgct ttggatttat
    14641 ttaatggaaa agatgatgta gtagatggta aaaaagttac tgaaatatta gttaaggcat
    14701 ttgactatga tttaactgga gaagtagttc acttggagag aaaaaatgga gacattatta
    14761 aagtttcaat tgtacaatag aattatttta tatgaatttt atttttgaat agttataaat
    14821 aattagaaat ttgtaaaaaa gtataatata ttattagtaa tggtacagaa tacacattta
    14881 taatttatag atgtgtattt tttgtttaaa aaatttaaat atataaaact ataaaggtta
    14941 caattttgga aatagatgta aatatatgtt gtattgtata ataagagtaa tataaaatct
    15001 agtaaaaata atcaaataaa tttagcttat gagagggata actatggaaa ataaggattt
    15061 taaattaaca atatgtatat ttgcttttgt aattggagta gtagtattat tctgttgtat
    15121 aggtttaggt gaatttagtg cagagcatat tattcaacaa aatggtggaa tcatggatac
    15181 tgaccaatat aatatttatc tagaccaatc tatttctcaa tatagaaatt ttggttctat
    15241 attagctctg ttaggaggaa tagggatatt gtttgataaa tatatcagaa aatactagag
    15301 attatgtttt gtctaaaata aattcttatg aggagataaa aaatggcaac agaaatattt
    15361 actgtaaaaa ttacaccctt agaggcacaa aaaatgataa aagaaaatct tgatgcagat
    15421 ttagttttta gtgattctta taatttagga gatgataaat ttatactaat tacaactttt
    15481 gagaagtatt atgcaagaaa taatagtgat gcaggattaa tagtagttta tgaaaatacc
    15541 acaggaaaaa cagttattaa agctacttca acaggcagtg caattggaat tttaaaaatt
    15601 gattggggtg caggtggaaa tttacttaaa agagtaaaaa acatacttgc tgattatatt
    15661 atttaattat tttatctaac tgataatatg tcaagaaaat ctcgtaaaag aggttaagaa
    15721 catttttata atatatagat aaataagaat ttgaaggtaa agtttttaag gtataaagaa
    15781 aaataatata ataaaacgaa ttggctttat aattctttat aaggcaaaga gcacatttct
    15841 ttatataatt gttggatatt aaataatatg taaatacacc atttacatat aaaagtttaa
    15901 ttaatatgtt aagagaaaat gaaatggaaa ttactaaaaa atatttttaa attggataat
    15961 ggttgatatt atgtttatac aaaaatcatg tagaatttta tatattttaa atatgatagt
    16021 ttaaaattat gaaagaatga taaattccag tttgtagggt aattttgata aataatatta
    16081 ataagtatga gtaaaaagta ggagcatatt aatataatgt ccctactttt ttattattaa
    16141 aattgtttat aatatcaaca ctacattaaa acacaaccta aatttgaaaa acaaatagtt
    16201 tagaaatatg tactttttta tctattatat tcttttaaat cgaatttttt catctgaaca
    16261 taaagtctca aatctatatg cgtctgtcat atcataaaaa ccaaaaaata taaagccatc
    16321 acgagaagta aattcatatt gtatattttc aattttcaac atgttttcta cttcgcttat
    16381 tttttcgcta tatataattt ctaccatata atttatcatt gtagaatccc tcctattaat
    16441 atgaaaatat ccaaatatat aataacatat ttagatgata taatagtatc caaataaaaa
    16501 ataatattat tacattattg aatgaagaat taaaatgaag ataaataaaa caaatattgg
    16561 ttataattga ttaaaaaata gttatgtata cttgtgactt tatttatggg cagttcaagt
    16621 tttatgaaag aagtcatata tatatggaat attctaggca gaaactgttt aataataaga
    16681 gaatactata aaaatttgag tattacataa aaaataagaa gccataaatg atataagcat
    16741 tatctatagc ttcttacttc tcattgatta agattatata taaaaataat cactatattt
    16801 tttgtttaag ttttagtact tgttttacta tatttgttga gtggtcagaa attctttcta
    16861 gattagtaag taagtcaaga taaagtacac cagcatcaat tgtacaactt ccattattta
    16921 gtctaatcat atgtgaattt ctaaaagttt tttctaaata atttacttca ttttcaactt
    16981 ctaaaacttt atttgctaac tcaaaatctt taacatctaa aactattaag gcatccttaa
    17041 aattagtaat tgtcttattg tatatttcgt atatttctct tatcgcacta tcagaaaaac
    17101 taatgttcat ttccttaaca ctcatggcca attcagctat attttctgca tggtcagaga
    17161 ctctttcaat gtcatttaca gtattaaaaa gcaaatctgt tctaaagcgt tcatcatctc
    17221 taagaggttc tttagaaagt tttaacaaat agttcaatat atctttctgt aacttattga
    17281 caactttttc tgactcaaaa gctttattaa tatcttcatt gctcttattt aaaaatcctg
    17341 caattgaatg ttccaaagag tttgtagctt tatgacccat tcttacaact tcttgtacag
    17401 tattaccaag tgctatagat ggagtgctaa acatcctttc atctaagtac ttagtattat
    17461 ttactatttc tgattcagtt tctttaatag gtataagtct atttgctaat ttaactatgt
    17521 atttagaaaa tggtaataat attataacat ttgtaagatt aaataaagta tgtgcatttg
    17581 ctatttgtct agctgtatca gttgggtcaa aatgagtaac tatggctgat ataggtttat
    17641 ttaaaacaag cataaatatt attgtaccaa ttacattaaa acttaaatgc attacagctg
    17701 cacgtcgagc atttctactt gcaccaacac ttgataaaag tgaagtaaca caagtaccta
    17761 tattatctcc ataaagaata ggtaaagcag atgatagagg aagtattcct tgagaagcta
    17821 gtgctattaa catacccata gatgcacttg aactttgaac aataccagtt atggcaaatc
    17881 ctgccaatat acctaataca ggatttttac taaaatataa aagtgcatca gtgaatgctt
    17941 tatattcagc aagtggagct actgcatctt tcataaactc cattcctgta aataatatac
    18001 cgaaacctat aagtatctca gataaatgct ttgttttttg atttgatgta aataaataga
    18061 ataaaatacc tatacctaaa gcaattggtg caattccttc aagattaaat gaaactaatt
    18121 gagcagtaac tgtagtacct atatttgccc ccattattac accaatagct tgacttagat
    18181 tcattatacc tgcatttaca aatcctacaa ccataacagt agtagcactt gaactttgta
    18241 taatacctgt aacgactgta cctaccagta cacccataac aacattactt gttaagagtt
    18301 caataatttt ttttaatttg tctcctgctg atttttgtaa accttctccc attaaactca
    18361 ttccgtaaag aaaaagtcca agtccaccga taaggctaat tactatattc acgatatttc
    18421 ctcccttaag aaattaataa tttttttatc tgaattataa actttattaa ctaaaattta
    18481 ttgtttccat aatatagaat aacaaatttt gtcaataaaa atattaatgt tttgttaagt
    18541 atacgttaag agaatgttaa atttttaagt tgttgttaat tttagaaaat ttatgatata
    18601 tagcaattta aatacttgaa cttagatttt tagtatttta tgtacaatca atttaacaaa
    18661 gaattaacta taattgtaaa aaatatgtaa aaaaataaca tccttttaga atgatatttt
    18721 ttagttataa atatttttat attcaattgg tgtaaagtta ttaaactttt taaaaattat
    18781 actatagtaa ttttgactat tgaatccaat tagtacagca acgtctaaaa tagacaagtc
    18841 tttttttaat atatactttt tgcttttttc aactctaact ttacttaaaa aattagtaaa
    18901 agtatatcca ctttttttct taaataaaga aaaaaacaac ttttattaag ttgtaattca
    18961 ttacatatat tacttactgt tatatcttct gagtaatttt tgtgaatata atctatagtt
    19021 ttctttaagt tttctttaca taaaactaag agttggtcta tgtttcattt tatcaaggca
    19081 tatttattaa aaaatcaatc tctatttgtt aaaataattt atgaatgatg ttagaaactg
    19141 taatatattg gatataatat aataaacaga taaactctgt attaagagga tatatagttt
    19201 atcttaatta taggggaagt gaggatatat tatggaaaga ttaatggaac tcatagaaag
    19261 aaaattttta aaggatgtag aacttttaga attagaagac atagaaaatg taatagaatg
    19321 caaaatgaca cagccatata atgctcatta taatgaatat ttagtaaaag taaaaaatgg
    19381 agatgaagta gaagaatatt ttgtgtattt aaaacataga taaacataaa agaggtttat
    19441 atttatttgt atgattataa aataaataca agcctctttt tttgataaat ataaaattat
    19501 aaaattttta tttatttaat tttttcaaca acattagtca atattgaatc taaatcatca
    19561 ctaatttctg taactccatt atgagtaata tctataattt ctttagtcat aggaagttct
    19621 cctaaaagct ctaagtctaa atcatctaaa aacttttcag tagattctcc ttcaaataac
    19681 ttgatttttt tagaacaatc aggacattgg atataactca tattttcaat aactccaagg
    19741 acatttatgt tcattttttt agccatatta acagcttttg atacaatcat agataccaaa
    19801 tcttgaggta ctgaaaccat aactattcca cttataggaa tagattgcat aactgttaag
    19861 gcaacatctc cagtaccagg aggcatatct attaataaat agtctaattc ttcccaaaga
    19921 acatcagtat aaaattgctt tacaacccct ccaagtaaag gtcctctcca aacaacaggt
    19981 tcattttcat catctatcat aaggtttata gacattactt ttatgttatt tgagttttct
    20041 acagggtaaa tataagagcc atcagaataa gcttttacat tttttacacc cataagtcta
    20101 ggaatacttg gtccagttat atctgagtct aatataccaa ccttatatcc cattttgttt
    20161 agcttattag caagtaaagc agttacagtt gattttccaa ctccaccctt cccactcata
    20221 acaccaatta tttttccaaa tttattgtta gggttatttt caatagaaca atttgattga
    20281 ctattacaat ttccctttga tggacatgaa ttacaatctg ccatatctat tacctccaaa
    20341 ctttaatatt tattagatta tttgtaacct acatatacta ttttagtaca attgaaccat
    20401 aaagtcatta tttaaaagca acttagaaga ttttctattg atttattcat agactatagc
    20461 aaaaagaata caataaaaaa attataacat tcttgaaaaa gtgattattt caatttagtt
    20521 atagaactta gtcatataaa tatatagaaa atattttaat atgttataca taacgggtta
    20581 ttttataagt ttaactataa attaggttta tattttataa aaatttgcta aaaaaaacaa
    20641 ttaaaaattg taaagaaaaa agatataatt agaactgtag taataaatgt tttattatag
    20701 ataatagagt tttaagtatc ttaaataata tttggaggaa tatgaatgga attaagacca
    20761 agaagtgcaa aattagaaga atttgataaa gtaatagaat taataaacta tgtatttaga
    20821 atatcaagaa atcataaacc aactatgatg gaagaatttc ctcttttact aagtaaaaat
    20881 aatatagaaa atatgattat aatatcagaa gatgataaag tgatttctga tgtaaactat
    20941 ctaattcagg atgtatctat tcaaggaaac agattgaagg ttgcagctat aggtggagta
    21001 tgtactcatc cagattatga aaagagaggc tattcatcta agatattgga taaagtagaa
    21061 gaaaaaatgt tttatgatgg tgtagatatt gtaattatat caggaacaag aagtctatac
    21121 agtagaagaa attgtagttt ggtaaagagt ttttataaat atacaataaa acctgaagat
    21181 gtaaaaatag catatgaaat agttgaattt gatgaaacta attttgaaaa agataatgat
    21241 ttagataaaa tgattgaact atataatcaa aatagtacta gatttataag aacgagagat
    21301 gagtttcaaa aactattgca tgcagcaact attgcctggg gaccaattgg ttacaagaag
    21361 gtatttataa aggaaaataa taatataata ggatatttga taataagaac aataaaaaaa
    21421 gaagattcta ctgtaggaga agttgctgaa atagggttaa actctgtaaa tgttgaaaat
    21481 atattgaaat atgttgcaaa taaatttgga ttagaatatt taaattataa agtacatgtg
    21541 aaaaatctta aagaccagtt gaaatgtaat gggacaaaat ctttggatta tcaacaagga
    21601 actatgaaaa taataaattt tactaagttg tgtgatagtt taagaagtta ttttagtcaa
    21661 tatgtagatt ttgaattact aaaatacatg gaatttaaac aagttgaaaa taaatatatt
    21721 attaaataca aagaagaaga acttgtaata gaaaatttgg ataagcttaa taaactgttt
    21781 tttgaaaaaa atgaggaaca gtacaatgaa tttaaacatc taaaaaatat atatgaattt
    21841 gctacaaagg catttcctgt agattttcca tggactgcaa atttaaatta tcaatagttt
    21901 tagatgatat taaataaaat tgattgatac ctagagttag tccttgttaa ataagagaaa
    21961 ttattggata ttgaaaaagc aattttgtaa gtaattagaa aggatgagta ttatatggac
    22021 atacttgatg atatagcaga atgtatatta aatatgggtg tagataatat agagaattta
    22081 gtaaaaattg ctatagataa aaatattgat gtggaagata tttatgaata tggtttaaac
    22141 aaaggtatga taggagcttt agataagttt gagaataagg aatactatct ttcagaagtt
    22201 atagtatgca cagatgcatt aaataaaggt attaatcttt tgaagggaac tggaaaagta
    22261 aagaaaaaat caaagggagt aattctgatg tctgtagtag aaggagatac tcatgagata
    22321 ggaaaaaata ttgtaaaagt aatggtagaa gccactggat ataaggttat tgacttaggt
    22381 gtaaatagaa aaagtgaaga tataatagaa gaagctataa aaaacaatgt agatataata
    22441 ggcttatctt caatgatgac aactacaatg gaaaatatga aatcggttat agacgaactt
    22501 aatatgattg agatagataa aagaccaaaa gtaataattg gtggaggacc tgtaagtatg
    22561 gagtttgcag aagaaatagg agcagatgga tacagttcaa atgctccaaa agcagttaaa
    22621 ttaataaata aacttatagg aggtgaagtt taaatgtttt cagatatgac tttacttcag
    22681 tatataaata gtgaagatag aggttttttt ctgcctgata tgggtacaaa tggattgttc
    22741 ttaataaata aaaaggcata tgaagtatat gatagtgtag atttgcaatt agaattagca
    22801 aagactatgg acaagtattt tgaatcagat tttatatact cattctgtga tgggattaca
    22861 ttttgtgaaa ctctgggttt agagacatta agaccagatt atgattttcc aagtgtattg
    22921 acacatacta taactgacag agataaatta agaaaattag atgttccaga cccttatacg
    22981 agtggacgta tgccactcaa tatagagagc ttatcagtta tatcaaaaag tattaaaaaa
    23041 ccactatatg aatcgataca aggtccattt acacttgcag gtcaattagc tggagctact
    23101 caacttttaa gatgtataat aactgataaa aaatttgtag aagaattatt ggaatttaca
    23161 actgaattgg taagaagata tgctgtagct gcaaataaag caggagcaaa atatatttca
    23221 atagcagagc caacatcagt aaccctaagt aaagatagat ttgatgaatt tatagtaaaa
    23281 aatttaaata aaatctacaa tgaacttgat tgttggaaag gtatgcatat atgtggagac
    23341 accagagaat tattagataa tatgctaagt tgtaatatag atgcagtaag tttagaccaa
    23401 attttagact atgaagaaat tgctccaatg attcctagag atatagtttt gattggtaat
    23461 ttagacccaa taaaacttct tggacgttct aagccagata agattagaag agagacgcta
    23521 aaattgttaa agaagatgag aagatatgat aactttttat gtgattttgg ctgtaactgc
    23581 ttaaatacca ctccagtaga aaatttacaa gcagctataa aggcaggaag aattagttat
    23641 aaagaattag ataggattga tattgatgaa ttataatagt aataaaaata aatatctttt
    23701 aaaggatata aatttagatg atatttttat agataagaat attgtgctaa agtttttggg
    23761 gtatggaaat agaaaagctc cagatacaat tagtaaaatc gttgaaagag aaataagaaa
    23821 tataaatgat attttagata tcaagatata tataagtgaa gttgatatta ataaaacacc
    23881 taaagaatgt aaaaaagcat ttgctgtact atatacaata ggggataaaa ttgatattaa
    23941 gatgaatgac tatatggaaa attgcaatat gatggcaggg ctagcattgg ataaaatagg
    24001 tatagtatgt ttagattata ttaatgagaa aataaaaatg tatttaaaag gaaagtatga
    24061 tagtctcaaa atatcgcatg aaatatatcc aggagataaa gattttgaag tagagagaca
    24121 aaaggatatt tataactatg taaaaaataa atataatagt atagaaatag aaattaatga
    24181 ttatcatcaa ctatccccca taaaaagtgt tgcaatgctt attttaatgg gggatgaaga
    24241 aaatttagaa tcaagatgta gtaagtgtcc tagaaaatgc ttttagttaa ttttcaagac
    24301 taagatttgt tttgtgtata aattgcaata atttttttgg tcattttatg tataaactaa
    24361 aaaaattatt gcaaagtaat attctattta atttgaacag acttacaaac tatagtagtt
    24421 tctttaattc aataagtgta tttatttcat aagttggtat atgattagta taatttatac
    24481 tgttattgga atttaaccaa caagtatcta ttcctgaatt tattccacct aagacatcag
    24541 aggttaagct atccccaatt attaaggcag aagatttatc atgacaatta aactttttga
    24601 gagcgtattt aaatatttca ggatttggtt ttgatatttt caactcttca gatacaacca
    24661 ttccatcaat atatcctttt atttttgaat tttcaagtct tttattttga actgcagaaa
    24721 ttccatttgt tattataaca atagtatact tttttttaag atattgtaat atatcgattg
    24781 cacctggaat taaaaatgta cattcaccta aaaaatttaa gtacattttg ctaagagttt
    24841 cagaatcaac atccaaagat attttatttg caaaaagttc aaatctaagt aatttaagtt
    24901 cattcaaagt tataatattt ttttcaaggt cgagccaaag cttatcactt atatttctat
    24961 atgactctat ataattctca aaattaaatt ctaaatcaaa ctcagataga agttttttaa
    25021 aagcatgtga ttcacttttc ttaaaatcaa ataaagtatc atctgcatca aaaaatataa
    25081 atttatatgt cttcatggtt tttactcctt tacaagatga ctgcaaaaat tactttactt
    25141 tcactatttg agtcattttg ccatttatgt tttgttccta aaggaacttt tacactatct
    25201 cctttggaca aagtaaattc atcatcatcc ataaaaagtt taacttctcc ctccaaaaca
    25261 tatgcaattt catctccatt atgagtaatc ctatcaacac aagaagaagt gtttggagct
    25321 aaatccataa ttgcaaattc taaattacca ctagagtctg gaattaaaat ctcatatata
    25381 acttctttgc ttccaggtaa aataactttt tttctattat catgtcttac tatcaagttt
    25441 tttttatcta cttcagatac aaaaaatgta aataaaggaa catttagaga agaggctata
    25501 gattttaatg aatttacaga tggattagca agacctcgtt ctatttggct caataatgat
    25561 ggtgtaacat cagctagttt tgctaaatct cgaatactta agttttgttt ttttcgaact
    25621 tcagctattt tttcccctaa atttaaatca ttcatataaa tatcctctct ttttaattta
    25681 aaaaatatta acttaaaata atcaagtaaa atgattatgt agtatgaaat tattataaca
    25741 tatagaatta ggttttgaaa aaactatgtt caatataatt aaataaatta aaatataatt
    25801 gacaaagtgg atacagaata cttaaaatat atttaaataa aattaagcaa aagatagtta
    25861 atttatgata ggaggggata ttatgcaaat aacgactttt ggagctatat ttggtttatt
    25921 aatagcaatt attttaatta taaaaaaatt tcaagctgta tatagtttaa tgttaggagc
    25981 atttattgga ggattagttg gaggagcaaa tataacacaa actgtagatt ttatggcaaa
    26041 tggagctatg aatatatcac catcaattct tagagctttg gcatcaggtg tattagctgg
    26101 aagtttaata aaaacagggg cagtagataa aatatcagaa cagattgtaa aaatatttgg
    26161 tgaaaagagg gctttatttt cgattgccat ttcaactatg gtacttgctg gagtaggtgt
    26221 aaatttggat gtatctataa taactgtagc acctatagga ttatatatag gtagaaaatt
    26281 aaattattct aaattgtcaa tactattagc tatgttggga gggggtaaag caggtaatat
    26341 aatatcacca aatccaaata ctatagcagt agcagataat ttttctgtca atctctctag
    26401 tgttatgatg gcaaatataa ttccagcaat tattggagtt gttattacag ttattttagc
    26461 aagtatatta ataaataaag gaaataaagt acaatcatat gaaattttag agcaaagaga
    26521 agatttacca agtttattta aatcattatg tggtccaatt atagctatat ttctattgtt
    26581 tttaggaaat gtatctccta tagttataga cccaatgata gcccttccaa taggaggaat
    26641 cgtaactcta attgtcacag gaaacttgaa caattcaaga gaatatttaa cttttggatt
    26701 atctaagatg caaggggtat gcatattatt acttggaaca gggactatcg caggaattat
    26761 acagatgtct gaattacaac agagtacaat aggtgcttta caatttttaa atatgccaca
    26821 atttttattg gcaccagttt cgggtatact tatgtcatta gcaacagcat catcaacagc
    26881 tggtgctact atagcatcat ctacttttca tgatgctata ataaatggtg ggctatcacc
    26941 gatttcaggt gcatcaatag taaatgctgg gtctagtgta ttcgagcaat taccacatgg
    27001 ctcactattt catactagtg caggtagtat aaacatggat ataggtgaaa gatttaagtt
    27061 aattccatat gaagcattga taggaatagt aatgactata atttcaacat ctattcaatt
    27121 agttttataa taaatataaa tatttaatga aaaaagtagg attttgttat taaatattga
    27181 acttattata gtaaaaaaga agattggagt tttaaagtga ataaaaaaaa gattgttatt
    27241 atagggatta tttattcatt tttagtagta ttttcactta caaatatgta tgtaaatatg
    27301 gagtataatc taaatgtatt tgaatatatt aagaagtcac ttccatttac agaagaagaa
    27361 aaaaagtggt tagaaaaaca caagaatttg atttacagct ctgaccaaag ttcacctcct
    27421 ttgagatata aaggtaagga agatggacag tataagggaa ttattgttga tttaataaat
    27481 tctctgtcaa ttcaaattgg tagagatttt tattttaaac caaataattg gtggaaagaa
    27541 tctttcgtaa attcaataga tgatagtata aagttttttg acttgattcc atcaaaagaa
    27601 agggcaaata aatttatatt tactgaccca atatacactt tgagtgcaaa tatattgaaa
    27661 gataaaaagt cccaagatat aaatagttac atggatttaa aggggaaaac agtagcaatt
    27721 ccagaaggtg attattctat aaatttttta aagcaaaaaa ttcaagatat aaacatttta
    27781 ttgactccag atataaagac tggagtcaac catttaatgt ctggaaaagt agacgcagtt
    27841 gttggtgatg aaccagtatt gcgatactat ataaataatt atggactttc aaataaatac
    27901 agtgttttaa gtaatcctat atatactaaa aaagcagttc ttgctgtacc taaacaatat
    27961 gaagagctgg ttagtatttt aaataaaggc atttttaaac ttcagaaaaa tggagtgtat
    28021 aaagatttaa agaaaaaatg gtattctacg tataatgaag ttgatgatat attgtatgag
    28081 cgaggaattg tgcctagtat ttatcttttt ataggtataa ttttaatatc aatttatgtt
    28141 ttttatagct atacatattt gttaaagata gaaatcaaaa ggaaaacaga acaggtaata
    28201 gaaaataaaa aaactttaga ggcaactttt aatagtatta cagatataat aatgcttgta
    28261 gatgaaaata acaatatagt agaatcgaac aaagtactat atgactttat gggtgaaatg
    28321 agttataaga tagcagattt gattagcatg ataaaaggtg ttattgaaaa taccttctct
    28381 gaaaatacta ataaaactag tgaaatagaa atacacaata aaattttaaa gataaacact
    28441 tttcctgtag agtataaaaa aaataatact gagtatatag tagttcttat taaagatata
    28501 actaatgata aaatagtaga ggcgaaatta cttagagaaa acaaaatgat atctataggg
    28561 caattagctt ctggggtagc acatgagata agaaatcctt tgggtataat aagaaataat
    28621 tgctatctct taaaagataa cgttacaatg gaagaagtaa atgattgtgt taaatcaata
    28681 gaaagtaatg tagatagggc aagtaatata ataaccaact tgttaaattt cgcaagaata
    28741 tcagatgata atttagaaca tataaatata aaaaatttta ttgaaaatat agtgaaactt
    28801 caatataaaa tgttacagtt aaagaatgtt gaaataaaaa ttgactgtga acataattta
    28861 atatgctata taaatggaga atcgttaaaa catgtattta taaatttaat ttctaattca
    28921 atagatgcaa tacatcaaga tggaaaaatt attatatact gttatgaaaa aaatcattgt
    28981 ttatttatag attttaaaga taatggtgaa ggaataaaag aagatgtcct aaaggacata
    29041 tttaatccct tctatacaac aaaaccaatt ggtgagggaa ctggtttagg tttatatatt
    29101 acttataatg agattaaaaa gaataatgga gatataagtg ttgaaagtaa attgggggtt
    29161 ggaacttgtt ttcatataaa aattccatta aataaagagg tgactatata atgaaaatac
    29221 tattagttga tgatgagcta gaatatggag tggtaatgaa aaaaattcta caaaagaagg
    29281 gctatcttgt agatatagca ctaagtggtg aagaagctat aaatataatt aaaaaagata
    29341 aaaattatga tttggtttta tctgatgtta tgatgaaaaa tatggatgga gtacagctat
    29401 tagatagaat taaatctatt aatagagata tagaggttat attagttaca ggatatggaa
    29461 gtattgaaaa tgcagttgat gctatgaaaa gaggagcttt atcttatttt ataaaaagta
    29521 atcccattga aaatttatta gaagaagttg aaaaggtaaa ggcaagtaaa atatctgttt
    29581 ctgtacaaaa aaataatttt gaatttactt tggaatctaa aaatagagat tttaataata
    29641 tcataaaaat agcaaaaaaa gctgcttgta aagatgttaa tatattaatc ttgggggaat
    29701 ctggtgtagg aaaagatata ttagctagat atatacatag cataagtcca agaaagaatg
    29761 agatatttgt acctgtaaat tgttgttctt tttcagaaaa tctattggag tctgagctgt
    29821 ttggtcatga aaaaggttct tttacaggag cagtagatag tagaaaaggt agatttgaac
    29881 tttcgaataa aggaactcta tttttggatg aaataggaga tatacctcta aatgttcagg
    29941 taaaactttt gaggacactt gaggacaaat ctatagagag gataggaagt aataaatcta
    30001 ttaaagttga ctttaggtta atttgtgcta tgaataaaga accaaaagtg gaaatatcaa
    30061 atggaaatat aagagaagat tttttttata gaataagtac aataacaata actataccac
    30121 cactaagaaa gagaagagaa gacttaacta ctcttataga atttttctta aataagtacc
    30181 aaattgaaca tgataaaaag atacactcga ttgataagga agtaaaggat tttttattaa
    30241 attacaatta tccaggaaat ataagagaat taaaaaatat aataaataga cttgtagttt
    30301 taagtgaaga aggtaattta tcaaaagaca atttaaattt aatatcaaat aatgtataca
    30361 tagatgataa aataagtatt agacctttaa gagaaataag aaaagagttt gaatgtgagt
    30421 atattgaaaa agttttatct ttgtgtggaa ataatatttc aaatacagct aaaaaattgg
    30481 agattagtag aagacagtta accaataaaa tatcagagta taatattaag tgagaaaaaa
    30541 acttctcatt aagtgagaaa aaaatttctc aaactgtatt aaaagataaa cagaaaaaat
    30601 ctgtttatct ttttttatta taattttaaa aattaatatt tacaataatt attgctaaat
    30661 tcaatattgg tgtaaattaa aaatgaaaat ttctatgaca ttaatacata gaatatatat
    30721 tttaaataat tggcatagaa aatgctttat atattaataa acgtaataaa tacttttaat
    30781 tgcgattaaa tatattaagg gggattttca tatgaagcta gagctaggga atatatttat
    30841 aaaaaatgtt gaatttggag aaaagacaga agtaaaagat ggagtactat atattagtag
    30901 cgaagaaata gaaaagatag tattagaaga tgaaaggatt gtaagtgtaa atgttgaact
    30961 tgcaagacct ggcgaatcaa taagaatagc tccagttaaa gatgtaatag agcctagagt
    31021 taaaattgga gatgaaagca aaatatttcc tggaattata aataaagtga agactgtagg
    31081 aagtggaaga acccatgtac ttttaggagc ttgtgttgta acttgtggaa atatagttgg
    31141 atttcaagaa ggcgtaattg atatgagtgg tcctactgct aaatatacac ctttttcaaa
    31201 aacaaataat atatgtattg ttataaaagc aaaggatggt atagatactc atgattatga
    31261 agaagcagct agaattgcag gattaaaaat aggtgcatat gtaggtgagg caggaagaga
    31321 agttgagcca gatgaagtca ttgtatatga gacaaagcca ttattaaaac aagtaaaaga
    31381 atatccagac ctgccaacag tagcatatgt tcacatgtta caatcacaag gacttttaca
    31441 tgacacttat tactatgggg tggatgctaa acagatagtg cctacattta tgtatccaac
    31501 tgaaataatg gatggagcta taatatctgg aaactgtgta gcaccatgtg ataaggttac
    31561 aacattccat catttaaata atccagttat acatgactta tataaaagac atggaaaaga
    31621 tttaaacttt ataggagtta ttttgactaa tgagaacgta ttcttagtcg ataaagagag
    31681 aagctctgat atggtagcta aattaataga atttttagga gttgatggag ttctagtgac
    31741 agaagaaggt tatgggaatc cagatactga cctaatgatg aattgtagaa aatgtagtga
    31801 agttggagca aatgtagttt tgataacgga tgaatttcct ggaaaagatg gcaagagtca
    31861 atctatagca gacgctacta aggaagcaga tgcagttgtt tcttgtggtc aaggaaatct
    31921 agtggttcat ttcccagcaa tggaaaaaat tataggaact ttagattatg ttgaaatgat
    31981 gataggtggg tataaaggat gcttaaatga agacggaagc atggatgcag agctacaaat
    32041 tataatagca tcaactatag caaatggcta taatcatttg acagcaagat attattaaat
    32101 aagtatttga atataaagtt ctgttgatgt aatcattggt ctaactgatg taataactat
    32161 aaagtgattt ggaggattaa gagatgagta aaatcagagt ggttcattat ataaacaatt
    32221 tctttgctgg tataggtgga gaggaaaaag cagatattcc gccagaaaaa agggctggtg
    32281 tagtaggacc tggaatagca tttcagagtc aatttaatga tgatgcagag ataatctcaa
    32341 ctgtaatttg cggagatacg tattttggtg aaaatattga gagtgcaact caagaacttt
    32401 taaaaatgat aaaagaagaa agccctgatt tatttattgc aggcccagca tttaatgcag
    32461 gtagatatgg agtagcttgt gggactattt gtaaggcagt tgaagaagag ttaaatattc
    32521 ctgtaattac aggcatgtat aaagaaaatc caggtgtaga tatgtttaaa ttagatttgc
    32581 atatagtgtc tacaggaaat tcagcagcaa gtcttagaaa ggtagttcca ataatgacga
    32641 aactaggtct taaattggtt agaggtgagg aaataggacc tcctgaagag gaaggatata
    32701 taatgagagg aataagaaaa aatttcttcc atgaacttag agggtctgaa agagcaattg
    32761 atatgttggt taaaaagatg aaaggggaaa gctttgaaac tgagtatcca atgcctgaat
    32821 ttgatagagt tacacctatg aaacctgtta aagatttatc taagataaaa cttgccctag
    32881 taacttctgg agggatagtt ccaattgata atccagacaa aattgaatct tcaagtgcta
    32941 ctaaatatgg aatttacgat ttaacagata tggattctat gtcaaataaa gaatttacaa
    33001 ctatacatgg ggggtatgac agagcatatg tccttgaaaa tccaaattta gttgtaccac
    33061 tagatgtagt tagagagctt gaaaaagaag gtgtaattgg agaattagta gattatttta
    33121 taactactac aggaacagga acgagtgttg gcaattctaa gagatttgga gaagagtttt
    33181 ctaagaaatt gttagaagat gatgtagatg ctgtaatttt aacttctaca tgaggtactt
    33241 gtactcgttg tggagcaacg atggtaaaag agattgagag agctggtata gcagttgttc
    33301 atatatgtac agtagtacca atatcactta caataggagc taatagaatt gttccagcag
    33361 tagggatacc atatccactt ggaaatccta tgttaggaga agaggaaagt aaaaaaatta
    33421 gaaagaatat agttttaaaa gctttaaatg cactaacaga agatatagaa gaacaaacag
    33481 tatttgaata ataaaaatac aacacaacac tgaaataaaa aaagatatca aaaaataatt
    33541 ttttaaaatt attttacgat atcttttttt attaggtaaa ttcgaaattt gcattttttt
    33601 aaattaaatt tataaaagtg ataaattagt ttattataat attgatacac aaattcaaat
    33661 tagatatact atgaaaagcg agattattac attttggaac aaatattcaa catattagat
    33721 catattaatt gaacagaaaa aattaacttt atataataat tagaataatg ataagaaaga
    33781 aggtgtatat attgatttca attgccattt gtgatgatga atcctatatg ctaaatcatt
    33841 taaaggaaaa tatagaatta tacatgaagc agaagaattt attatataat atagagcttt
    33901 ttaataaagt agaagattta ctatgcaatc atgaaaagtt taatattgta tttttagata
    33961 tacagatgga agagattaac ggaatgcagg cagctagaaa attaaggtca tatggtaatg
    34021 agtgctttat aattttcgtt acagttttaa atgaatttgt atttgatgct tttgaagtag
    34081 atgctataaa ttatctgata aaacctctat ctaatgagaa actatataaa actttggata
    34141 aaatagttac aaaacttgat gataatgaaa gtaattatat cacaatacaa aaaggttatt
    34201 catattggaa attaaaactt gctgatattt tatattgtga agttataaaa agaaagattt
    34261 atgttcattt aaagaaagag actgtagatt attatgagac tattgaaaat ttagagagaa
    34321 gtttaccaac aaattttttt aggtgtcatc gtagttatat aatcaattta caatatgtat
    34381 atggatatga aaatggtaat gcagttatgg aaagtggaga tagaatacct gtttctagac
    34441 tacgtcaaca aatattttca aaagttatgc ttgagttcat gaaaaatagg aggatataag
    34501 atgattaatt tattttcttc cgatttattt ttaaagtaca gttttttctt ctcttttatt
    34561 gtatatagaa ttttaatggt aatagtgcaa tactattttc taatcaattt tacaaatttt
    34621 aattcaaaat tttggtgttt tattttatat tcgataattt caattttttt aatcattata
    34681 aatacatatt ttaatttata taatttattt tcttcacaga ttctattttt tcttatgact
    34741 tttttatttg taaagtacat aataaaacaa tctactgttt tatctatagt atcaactttg
    34801 ttagtatatt taattgaaca attagtatat ggatttacag ctccattaaa ttacttgata
    34861 tttactagtg atataaatac agatatttat aaatttgata taaatatggg actatcttct
    34921 ttaattacta ttataatagc tggatttata tattggtata gttctaaaaa gtttaatatt
    34981 aaggtcatga actttgataa atatatagca attttgatga ttccattgtt gcttataata
    35041 ttatttatgc aatcatttga atatagttca aatataaata tagatacaag tcttgggatt
    35101 gtaaagctgc tattaaatac ttctataact gaagaaattc aagcttttct tttttctata
    35161 attggaacta tatgtgtatt tttttctcta tttaccttta agaaactaat tcaagctctc
    35221 gaagatgaca aggagagggc aattatgaat caacagattc atgctcaaaa aaactatatt
    35281 gaagaagcga aatcacgatt atcacaaact atatccttta gacatgattt taataatcat
    35341 ttagctattg tcaatggatt gttgaaaaaa gaccaaattt taaaagcaca agattattta
    35401 aataagcttg aaaaagtaac aagtgaccta tcattttctt gtaatacaca gaatattgtt
    35461 attgatgctc ttttcaacaa taaattaagt atagcaaaac aattaggcat agaggtagat
    35521 tgtgaagtaa ttatacccca aagcactaac atgaacgatt ttgacctatg tatagtgttt
    35581 gctaatgcta ttgacaatgc aattaaagct tgtagagttg tagataaaca aaataggtat
    35641 ttaaagcttt ccactaagtt agagggtgga ttttttatga tagaaataaa aaatagctat
    35701 aatccaataa ataattatac aagtggctca ggtataggtc ttttaaatat aaaagaaatt
    35761 gctaaaaaat atcaaggggc tataagtata gataagacat cagactattt tcaaataaat
    35821 gtattgctag ttatttcatt acattgcgct agtatttgag aacaatttca ttgaaaatag
    35881 tatttgtaag ctatattatg tatttgaaaa gagaaagttt gatatataga aatgaggagg
    35941 ttactaaaat gaaagttgga aatataaatg gtcaagcacc aattacaaat ggtttagata
    36001 gttgtcaaag tgaggtacaa ggcttagaac aaaagaaaaa agcattacag gatgaaatag
    36061 agaaagtaag aagtgataaa agtattgatg gtgaaacggc caaattaaaa atagaagctt
    36121 taaaaaaaga aatggaagag attgaaaata aaattcaaga gttaaaagga aataaaggaa
    36181 aaaaaacaaa taaagaagaa aataacgttt cagaagtaaa taataatcta ttagagagaa
    36241 aaaaagaacc ttctaataat gaaaatgtaa aacaattata tgatgttttt gaaagaagca
    36301 atgtagacga acaatgggat aatacttatc gtgttctcca agatgataaa aacttaaaag
    36361 taaaatttaa tagacctata tagtttattt ataaaaatag ttaatatttt aattatcacc
    36421 actttttaga agaatacaca ctttatttta aagacccaca tatttattta cagttagcac
    36481 atttatatgt ggttttataa ctattattta caagtctata ttgataactt ttacatagta
    36541 tatgatgttt aaatacttat tcaaatttat ctatacataa acaaaaaaag agattttaaa
    36601 atctcttttt agattgttga cttatggctt tttgatttaa taaaatcaag aagccgtttg
    36661 aattttatat gttggctgat acccttctga tattgaaaca ccatttttgt ttccaaaatc
    36721 gtttaaaatt aagaacttat tatgaatgac tatttcatta tgaacaataa gcaaataaca
    36781 tgaatcttca atcaatgttt taacagtagc attaaatgct tgcttatata gttctatcgt
    36841 ttgtttgaac tgcccattaa agtaaatatg agtcaataac ataactatat ctacacaaat
    36901 taatataaat tttttatact gtacattatc taactgttga ttatctgtat tacaacatga
    36961 ttgaatttaa aaagccatca acacatagaa tgttgatggc ctgaaaatag attttaaaat
    37021 ctctttttta ttatatatta attatttttt aaatttatat tttttgcatc agattttcta
    37081 atagctaagt caaaccctct aaatctaatc actatagggt cattaagagg agctatcttt
    37141 ttcacttcaa cttcagtgcc atctattagt cctaaggcta gaagtctctt cataagtttt
    37201 tcatttccag ctatattgtc tataattccc ttttgtccaa gttttaagtt gtaaacagtc
    37261 attattaaca cctcctaatg aaaatcatta tcaaacttta tatttataat atataacaaa
    37321 aagagcaaat tgtcaatata taacaaaaaa taaacatact aagttagtat gtttataaaa
    37381 aatagtatac atgggatact aatagcatct agcaaaaaac cacttactaa tggtacaact
    37441 aaaaaggctt ttggagaatc accatatttt tgtgtcaaag aactcatatt tgccagagcg
    37501 ttcggagtag ctcctattcc atgtccaatc aaaccactta ttatgatggc agaatcaaaa
    37561 tcttttccaa gtactctaaa gcaaataaat attgaaaata ggattataaa gattacttga
    37621 aaagttacta ttaagagaat aggaggtaat aatgtagata attcaaataa atctatattc
    37681 ataagtgata aagttaaaaa aattcccaat gaaagttctt ttaaaaaatc tataagttta
    37741 aaatttaatt ctagtatatt tatcttatca tttaaatttc taaaaataac agccgaaaac
    37801 atacaagtta caacagaggg taatagtata ttaaacgtta tatagaagca tctacttata
    37861 atttctcctg tatttataca aataaatatg agaagaacct gttccaaaaa tacagatggt
    37921 gttattgttt cggagaagtt attatttttt atcctattct tatttctaaa aaatttactt
    37981 ccaaatctct ttagatttct attatatcta ggaatcgaca agtctatatt tgatgatggt
    38041 tttaatttat atttatttat tagaaattta gctacaggac atcccaatat accacccata
    38101 ataagtccta ttgttgcagc agataatcca accccaactg ctccttctat accaagattt
    38161 tctattgtaa gtccaaatgc agcagaataa ccatgaccac cttccataga tacatttcca
    38221 cacataagcc ctaaaagagg ttcaagtttt ataatctttg atattgtaat agctaatata
    38281 ttttgacaaa atgccaatac tccacacaaa atccaatatc taaataatac actaccacct
    38341 ttctttataa gatttatgct tatttcaagt cctatagttg taaaaaagaa ggttatgaaa
    38401 tttggcatta aatttccact tatagatata tctgctatat taaaatattt aaaaaataaa
    38461 tttagaaaac aaaataatag acctcctatt actggtgcag gtatacagaa attatttaaa
    38521 aagttaactt tattcttcaa taaattacca attaaaaaga agaatataga tagtgtcaag
    38581 gtttgcacta tatcaaaact taaggtaatc aaaataagtc ctcctttgta attcaaagtt
    38641 ttaattatat aacttaaatt cttatgtatt gaaattttat tatcaaatgt atattaataa
    38701 atgtatatta aaaagaatca gtagatataa ttagatagtc ataaattaaa ttaaaatatt
    38761 ttaatgagat atgacttttt tagaattaaa aaccgtagta tattgatata atagaaataa
    38821 gacttaaaaa tctgttgata gtattattta taagtacagt aggaggataa aatgtttgaa
    38881 aatttaccta agatagattt acattgccac ttagatggaa gtgttagagt agaaaccatg
    38941 cttgatatag ctattaaaga gaaaatagat ttaccttcaa ataatatgga tgaaataaaa
    39001 aaattagcaa aggtttcttt taattgtact tcactagatg aatatttaga aaaatttgat
    39061 ttacccttaa aagtaatgca atctaaggaa aatttaaaaa gaattacttt tgaacttttg
    39121 gaagatgcaa gtagagaaaa tgtaaaatat attgaaatta gatttgcacc attacttcac
    39181 acccaaaaag gtatgagtgt taaaaatata attgagggta taattgaagg aattagagaa
    39241 gctgaaagta tttatgatat aaaaggcaat ttaatattag gttgtatgag aacaatgacc
    39301 tcaaaagagg cattattagt aattgaagaa gggaaatcat ttgtaaataa aggtgttgta
    39361 gcagtagact tgtgtggtcc agagaaagag ggattttgta aggaatataa agatgttttt
    39421 aaattagcaa gagaatatgg atataaagtt acaatacatg caggagaagc tgcaagtgga
    39481 gaaaatgtat tggatgctat aaatatttta aaggcggata ggattggtca tggggtaaaa
    39541 attaaagacc ataaaaaggc gtataattta gttaaagata aaaaaatatt gcttgaatta
    39601 tgtccaacta gtaatgtaca aactaagaca gtagattctt atgaagcaca tccattttat
    39661 actttttata aagataattt acatgtaagt ataaatactg ataatagaac tgtatcagat
    39721 ataaatttaa gttcagaact aaatgttata tttgatactt ttaaactagg attagaagac
    39781 tataaaataa tttatagaaa tgcagtagaa gctagttttg cagataaaga aactaaagag
    39841 tatttgaata gtttaattta atagataaaa atatttaaac tttaaattaa gctattaaat
    39901 tgataaaaat acattgtatt aggagaaaaa atgtgaaaga ttatgaagat gttgtttata
    39961 ttaaactagt caaaaaagaa cttgaagaat ggaagaaaaa tatattaaag aaaccttcta
    40021 tatttgacaa agcatcaaag ggtatacaga ataaatttaa tggagtattg ccagataaat
    40081 atcatgaaat aattacttct tctataaaag taatgacaaa aaccgtactg tttggatata
    40141 aatatgctac aaagccatca cttagaaata tgtcattaga agaaagagaa aaattagttt
    40201 tagaaaaagc taaaacttac aagactacag caatgattga aggggcagga acaggggcag
    40261 gaggaatcct cttaggttta tctgattttc ctttgctttt aggtattaaa gtgaaatttt
    40321 tatatgatgt agcttcaata tatggatatg atgttaaaga ttatagagaa aggatttata
    40381 tattaaatat attacagttg gctttttcta gtcaacagca tataaacaaa acttttaaat
    40441 tgatgaataa ctgggatgaa tatgtaaata gtctaccaga agacatcaat gattttgatt
    40501 ggagaacatt tcaacaagag tatagggatt atttagattt agctaagttt ttacaactaa
    40561 tgcctggaat aggagcattt gtaggatttt atgtgaatgg aaaattaatt gataaattat
    40621 gtgaaactgc tgtgtctgct tatagattga ggattcgaga gcttaagtta taagagaaat
    40681 tataacataa aaaattagtt atacaatata tctatatgta tctaattttg cattgataaa
    40741 aacaattatg gataaaaggt aaagcatgat agaatctaat gtagaggttt gtattttaat
    40801 ggaaaaattt agtttttatt gcttaagata caaattgaat tacgaagaga agtaattggg
    40861 aggaatattt tcatgacaaa tttgccaaaa caatttgata gcttcaatga agctagacaa
    40921 aaaggattta taaatgcaaa ggaacttaag gaaagtggga aaaagatggt tggagttttc
    40981 tgtacattta ctccagttga aattccaatg gcagctggag caactgtagt aggtgtatgc
    41041 ggcgttagtg aagagccaat acctgatgca gaaagggtgc ttccaagaaa tctttgtcct
    41101 ttaattaaat caagctatgg acatgcaata acagatacct gtccttattt ctatttttct
    41161 gatttgttga taggagaaac cacttgtgat ggtaagaaaa aaatgtatga agaacttgca
    41221 aaagttaagc caacatatgt aatgcatttg ccaaatactt caaaaggaga atttgcctat
    41281 aaactttgga aagatgaaat gataagatta aaagaagagg ttgagaaatc tttaggtgta
    41341 actataactg aagaagatat aagaactgct ataaaagata aaaatgaaga aagagaactt
    41401 ttaaaagagt tttatgcact tggtaaatta caaccatctg cacttacagg ccttgagtta
    41461 cataatgttt tatatcaagc aggttttaaa tttgaccgtg cagaacttaa acattcttta
    41521 agaaaagtta tagatgatat gaaagaaaga tatgaaaaag gtgaatgtcc tgttcaaaaa
    41581 gataagccaa gaatattgat aacaggttct cctattggtg gaataagcga aaaaatagtt
    41641 aaaactttag aagatgcagg ggcatcagtc gttgcatatg aactttgtgg agctattaga
    41701 tcaaacgatt tattggttga tgaagaaata gaagatgtat atgatgcttt aacacaaaaa
    41761 tatataaata taggttgttc ttgtatgatg aataatgaca atcgtattga attattagat
    41821 agaataatag atgaatataa tgtagatgct gtaatagatg tagttttaca agcatgtcat
    41881 acatttaata tagaaagtta tagaataaga gaatttgtta caaaagaaaa aaataagcca
    41941 tttatgtctc ttgaaactga ttattcaaaa tcagatactg aacaattaag aactagattt
    42001 gaagcgtttg tagagatgtt gtaggaataa ataaaagtag gaggaactat gtttagtata
    42061 ggagttgact cagggtcagt ggcaacaaag ggtgtgctat ttgatggtga aaaaattatt
    42121 aagaaaataa ttataccaac tggatggagc cctaaaagta catctaaaca ggtctatgag
    42181 ttgctaagta gtgaaattga caaaaaagat ataaaaaagg tggtaggtac aggttatgga
    42241 aggggagtaa tggattttgc tgataagaaa gtaacagaaa taacttgtca tactagaggt
    42301 atttactttt taaacaagaa cataaggact attttagatg taggtggtca agatagtaaa
    42361 gttataaatt tagatagaga tggaaatgta tttaacttta taatgaatga taagtgtgct
    42421 gcaggaactg gtcgattttt agagattact tctaaccttt taggaagcga tattgaaagt
    42481 atagatacat tagctaaagg atatgaacca gttaatatat ctagtatgtg tacagttttt
    42541 gctgagtctg aaattgtaag tcttctagct caaaacattt ctactggaga ggtagcagca
    42601 gggatactta aatctattgc aaataaatcc acctcaatgt tagcaagagg tgaggtaata
    42661 gatgaagttg catttactgg agggcttgca aaaagtaaag aactagtaaa aatgatagaa
    42721 gaaatactgg gtaaaaaaat ttttattgca gaagatactc aaataatagg agctttagga
    42781 gctgctgtaa taggatttag ataaaaacat ataaaaggaa aatgagaagc tgaatttatt
    42841 ataaataaat tcagtttttt attttatttt atttatttat aaaggaaaac tttggtataa
    42901 ttgatttaaa tgattgtata tttgtaaata cttgatattt agtcatatat aacattataa
    42961 ttttaaaaat tagctcaaaa taagggggag aaagcgtgaa aaaatttact tcaaaaaaag
    43021 taacaaggtt tgttgcgctg tttttaatat ctattttagt aatgtcaaca attcctgtat
    43081 cagctgacaa tagcaataca ttgaatcaga taaaaaaagc agaatacagt gagacgtata
    43141 aacaatatct aaatgatgct aaaaatggac gtacagaaaa atataatggg attataccaa
    43201 atccatatca gttggaaggt actcaaatcc aaagtaaagg aagaacagct ccaacatctt
    43261 atgaccctag aaaattaggt cttatgacat caataaaaaa tcaagaggat ttaggaatct
    43321 gttgggattt tgctgcaatg gcaaccttag aaagtttctt aaagttaaat aattatggag
    43381 actatgattt atcagaagaa cacttaagat ggtgggcttc agatggtgaa tatggatggt
    43441 ctgtaaatga tatgaatggt gctttaaatt atgaagctat gggatattta acatcttggt
    43501 caggtcctaa actagaaaaa gatattccat acaatggtag agtatctaaa gcacaaggag
    43561 caaaaaaacc aactaatatg aatacagcac ctactgtttt taatgtgaca gatgctgtgt
    43621 gtgtaagtaa tgacataaat tctacaaaaa atgctatatt acagtatgga gcagtaacat
    43681 ctggttatta tgaagatatt aaatatcaaa gtgatgacca aaattcatat tattgtccaa
    43741 caaaaagttt taatacaaat catgctattt caattgtagg ttgggatgat aactattcta
    43801 aagataattt taatgcaaat attagaccat caaaaaatgg tgcttggtta ataaaaaata
    43861 gctggggaga ttataattct gagggtggat atttctggat atcttatgaa gacaagacac
    43921 ttatgtctga tatagataat ttttcaatca aaggtggtaa aaaaccaaat gatgatgaga
    43981 agatgtatca acatgactat gcaagtattg tacctttaat ttcaaaaaag ataacagctg
    44041 caaatgtatt tgatttcaat agaggcgatg aaactctaaa atctgtaatg ttcttaactg
    44101 aaagtatagg agctaagtat gaagtatatt atgctccagt agtaaatggt atacctcaag
    44161 aaaacaatat gaaaaaatta aaagaaggta ctgcccaata ttcaggatac ataacagttc
    44221 caattgattc ttttgatata ccagaaggaa agggtgcaat tgtagtcagt atagagggga
    44281 aaaatggaga gtcaactata ggttctgagt caaatgtacc aggatatgat acatttaaag
    44341 caaaagctaa tttaggtgaa agttatatca tagataatac tggaaaattc tttgatataa
    44401 atagagatag taacttctat ccgtgtaatt ttactataaa agctgttaca gaaaagtctt
    44461 ctggtgagag tatcccaaat gagtctttaa ttggtagtga tagatatgaa actgctatca
    44521 aagttagtca aaatggtttc aattcttcag aaaatgtagt tttagtaaat ggcagttcaa
    44581 tagtagatgc attggcagca actcctttta catctgctat aaattcacca atattattga
    44641 cacaaaaaga agctttaaat tcaaaaacta aagctgagat acagagatta ggtgctaaga
    44701 aagtatacct aataggtgga gaaaattcta taagtaaaga aattgaacaa caattaaaaa
    44761 gcttaaatat atcgatagag agaatatcag gaagtgatag atacaagaca agtttattat
    44821 tagctcaaaa gttaaatggt ataaaaaatg tatctcaaat agcagttgta aatggagtga
    44881 aaggattagc tgatgcaatt agtgtaggcg ctgcagcagc agaaaataac ataccaatca
    44941 tacttgcaaa tgaaaagagc gaattgcaag gagctgatga atttctaaat tcattaaata
    45001 tagagaaatc ttatattatt ggaggaacag catccctatc aaacaatcta gaaagtaagt
    45061 taaaaaatcc aactagatta tctggtagta gtagagacga aactaattca aagataatag
    45121 ataattttta taaaaaagat actttaaaaa atgcatttgt agttaaaaat ggaatcaaga
    45181 atcaaaatga tttaatagat ggattggcag ttggtccttt aggagcaaaa actgggtcac
    45241 cagtaatttt agttggtgat aaattagctg atagccaaaa agaagttctt aaaaataaga
    45301 ctttagaaaa agtaactcaa gttggtggag gagcaaataa aaatgcattt aaagagttag
    45361 taaaattaaa aagtgctaaa tagagtactt aagtattaac atatattagt gtgtattagt
    45421 aacttatctt aataaaagct gaaaataatt acttcaaatt attgataaat aagataatca
    45481 atgattgtaa agttttgttt tcagctttaa atttatgtag tataagttta aaaacataaa
    45541 aaagggttac tttatataga aatatagaaa atcttacatt ttatatataa ataacccata
    45601 tttaattaac tttttatagt gttctaatag atattattga acttaatggt aaatataatg
    45661 tgtaagtttc atttaaagtt ggattagatt catctatata tcttgagcaa agtgtaattg
    45721 ataagctatc tgcttctata atttcaccat atagaggaca actgctaaag taagaatgta
    45781 cttcaacata tttatttaag ttttcttgaa cataatcgta aaaacggttt tttgtagtag
    45841 tagccataaa atcaactcct ttatttttta ttaaagttga aacttttaaa aagataaata
    45901 tgattacttc tattagaaac taagttaaaa aataagcaaa tagatatgaa aattagaata
    45961 atatattatt tatatcttaa ttataacact agataataaa aaatgctata taaaattcag
    46021 aattttcgaa agtttttaag cttattttta aatatactaa taatactatt gacattagat
    46081 agaaaaagta ttatattgac tatataaatt attttagtca aactggaggg aaaagatgcc
    46141 taaatcgtat tctgataaag aaagagagta tataataaaa agacttaaag aagaagcaag
    46201 attgtgtatg gagcaatatg gtattagaaa aactactgtt gatgagcttg taaaacgggt
    46261 aaaaatacca aaaggaactt tttatctatt ttttcaatca aaagaattgc tcttttttga
    46321 ggtattaaga gatatacatg actctataca aaaagaaatc ttatatgaga taaatagagt
    46381 agatgaaagt attacatgtg aacaattgac agatatattt atgaaattct ataggatggt
    46441 tgatagtact tcaattttaa atcttatgat aaatggagaa tttgagatat tggtgagaaa
    46501 gttaccagat tctataattg aagaacactt tagacatgat gactttgaaa ttggagagat
    46561 tatatcttgc ataccaaatg caaaaaataa agacatagaa agctttagtg gagcatttag
    46621 agcagttttt cttaccatgc tatataagcg cgaggttgga agtaattgtt ttgaagatgc
    46681 tttaagatta atgataaacg gattagttat acaacttatg gaatagaatt taaattttgt
    46741 ttgctaataa cttttattaa aaattattaa caaacaaaaa aattatattt tattgaccat
    46801 atagtcaaaa tagtcaaaaa tttgaaaggg tgatattgaa tgattaaagt tgatgattta
    46861 tcatttagtt atacagagag agatttttta caaaatatta actttggagt aggaaaaggg
    46921 gaaatactag gatttttagg accatcaggt gcaggaaaat ctacattaca aaagattcta
    46981 attggaatga taactaatta tggaggaagt gtcattgtaa atggagtaga gagtaaaaga
    47041 cactcaaata aattttatga aaatatagga gttgattttg aatttcctag tttatatgaa
    47101 aagttgactg caatagaaaa tttaaaatat tttgggtctc tatattctaa aaaactacta
    47161 tctattgatg agttattaaa atcagtagga ctagaaaatg aagcaaataa aagggtatct
    47221 gagtattcaa aaggtatgaa atctcgatta aattttataa aagctttatt acataatcca
    47281 gatattttat ttttagatga accaacaagt ggtcttgacc catcaaatag caaggttatg
    47341 aaagatataa ttttatcaga aaaatctaaa ggtaaaacta ttattttaac aactcataac
    47401 atgttagatg caacagagct ttgtgacaga gtagcgttca ttgtaaatgg taaaatatct
    47461 gctttagata caccacataa tcttattatg tcaaaaggag ctattaaagt tagatatact
    47521 tactttgata atggagaaaa aacttctgaa tgttttctga acaatactgc taatgataaa
    47581 aatttgaata tgcttattga gaaaaataaa cttttatcaa tacatagtag tgaaccaaca
    47641 ttaaatgata tttttattga gataacaggg aggaatttac aatgaggcta aaaaatctta
    47701 ttttaggaga tataaagttt caatttaagt atggttttta ttttttatat ctttttttaa
    47761 gtattatata tatttgtatt atcaatgtat ttccaacttt tatgagagaa aaaatagcta
    47821 taattatgat ttattctgac ccagcagcaa tgggattgtt ttttatggga gctattgtac
    47881 ttcttgagaa aagtcaaagg gttttaaatt ccttagctgt atctccagta aaagtatctg
    47941 agtatatttt atcaaaggta atttcattag gagtaatatc tagtattgta gctatgttta
    48001 ttgctattac attaaattta gataatatta taatatcaac tataggtacc tttttttctt
    48061 ctattatatt ttctttgctt ggattgatac ttgcaagtaa agcatctagt ttgaatcagt
    48121 ttattgtttt aagtattcct attgagatta tatgctttat tccaccaata ctcaatgtac
    48181 ttcttgacac aaaatcatat gcaaatttgt acccttttaa tatatgtatt tctcttatta
    48241 gtggagataa aaattttata atgattaata ttttaatttt aatatcaatt ataataataa
    48301 tttattttat aacttattat tttatttgta gcagttggaa aaaggtaggt ggagtaaaac
    48361 tatgataaag attataaatg cgtttaaaca agagtttgaa caaattaaga gagatgctat
    48421 gctttttata gtatgtgttt ctccaatatt atgtggagta tttataaaat ttggaatacc
    48481 attaatacag aatatatcac ttaacaagtt ttattatcaa ttaaatttag agccgtattt
    48541 cttgatgttt gatttacttt tagcttttat tacacctttt atgttctttt ttgcttctac
    48601 aatggtcata ttgggagaaa ttgatgacag catttcaaga tatttaatag taactccgct
    48661 tggtaaaact ggttatctta tttcacgatt tggaatacca ggtatcttag catttattat
    48721 tactatgatt ctacttatct ttttttctct aactaaaatt tctttcttgt taaacttatc
    48781 aatttcttta ttagttttat tacaaggaat tattatatca atattagtg
//
LOCUS       DAYAKB010000026        45827 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.026, whole genome shotgun sequence.
ACCESSION   DAYAKB010000026 DAYAKB010000000
VERSION     DAYAKB010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45827
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.026"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..499)
                     /locus_tag="ACGI3L_001747"
     CDS             complement(<1..499)
                     /locus_tag="ACGI3L_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9197459.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTK"
     gene            complement(507..2270)
                     /locus_tag="ACGI3L_001748"
     CDS             complement(507..2270)
                     /locus_tag="ACGI3L_001748"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing SpoIIE family protein
                     phosphatase"
                     /protein_id="HFG9197460.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(2313..2774)
                     /locus_tag="ACGI3L_001749"
     CDS             complement(2313..2774)
                     /locus_tag="ACGI3L_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197461.1"
                     /translation="MLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKIDS
                     VFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKNNI
                     DISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            2964..3425
                     /locus_tag="ACGI3L_001750"
     CDS             2964..3425
                     /locus_tag="ACGI3L_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197462.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKV"
     gene            complement(3518..3688)
                     /locus_tag="ACGI3L_001751"
     CDS             complement(3518..3688)
                     /locus_tag="ACGI3L_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197463.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(3877..4098)
                     /locus_tag="ACGI3L_001752"
     CDS             complement(3877..4098)
                     /locus_tag="ACGI3L_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HFG9197464.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(4182..5408)
                     /locus_tag="ACGI3L_001753"
     CDS             complement(4182..5408)
                     /locus_tag="ACGI3L_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9197465.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(5470..6402)
                     /locus_tag="ACGI3L_001754"
     CDS             complement(5470..6402)
                     /locus_tag="ACGI3L_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFG9197466.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            complement(6491..7018)
                     /gene="hpt"
                     /locus_tag="ACGI3L_001755"
     CDS             complement(6491..7018)
                     /gene="hpt"
                     /locus_tag="ACGI3L_001755"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFG9197467.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            7247..8323
                     /locus_tag="ACGI3L_001756"
     CDS             7247..8323
                     /locus_tag="ACGI3L_001756"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9197468.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(8409..9617)
                     /locus_tag="ACGI3L_001757"
     CDS             complement(8409..9617)
                     /locus_tag="ACGI3L_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HFG9197469.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(9778..10167)
                     /locus_tag="ACGI3L_001758"
     CDS             complement(9778..10167)
                     /locus_tag="ACGI3L_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HFG9197470.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            complement(10271..11272)
                     /gene="asnA"
                     /locus_tag="ACGI3L_001759"
     CDS             complement(10271..11272)
                     /gene="asnA"
                     /locus_tag="ACGI3L_001759"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HFG9197471.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(11331..11586)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11720..12910)
                     /locus_tag="ACGI3L_001760"
     CDS             complement(11720..12910)
                     /locus_tag="ACGI3L_001760"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9197472.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEISRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(13191..14312)
                     /locus_tag="ACGI3L_001761"
     CDS             complement(13191..14312)
                     /locus_tag="ACGI3L_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HFG9197473.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(14373..14858)
                     /locus_tag="ACGI3L_001762"
     CDS             complement(14373..14858)
                     /locus_tag="ACGI3L_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HFG9197474.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(14860..15528)
                     /locus_tag="ACGI3L_001763"
     CDS             complement(14860..15528)
                     /locus_tag="ACGI3L_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HFG9197475.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            15918..17942
                     /locus_tag="ACGI3L_001764"
     CDS             15918..17942
                     /locus_tag="ACGI3L_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197476.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(18172..19359)
                     /locus_tag="ACGI3L_001765"
     CDS             complement(18172..19359)
                     /locus_tag="ACGI3L_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HFG9197477.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(19561..20832)
                     /gene="brnQ"
                     /locus_tag="ACGI3L_001766"
     CDS             complement(19561..20832)
                     /gene="brnQ"
                     /locus_tag="ACGI3L_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFG9197478.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(20973..21626)
                     /locus_tag="ACGI3L_001767"
     CDS             complement(20973..21626)
                     /locus_tag="ACGI3L_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFG9197479.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      21955..22056
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            22129..23472
                     /locus_tag="ACGI3L_001768"
     CDS             22129..23472
                     /locus_tag="ACGI3L_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFG9197480.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            23651..25015
                     /locus_tag="ACGI3L_001769"
     CDS             23651..25015
                     /locus_tag="ACGI3L_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9197481.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(25193..27058)
                     /locus_tag="ACGI3L_001770"
     CDS             complement(25193..27058)
                     /locus_tag="ACGI3L_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HFG9197482.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(27294..28511)
                     /locus_tag="ACGI3L_001771"
     CDS             complement(27294..28511)
                     /locus_tag="ACGI3L_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9197483.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(28711..29574)
                     /gene="aroE"
                     /locus_tag="ACGI3L_001772"
     CDS             complement(28711..29574)
                     /gene="aroE"
                     /locus_tag="ACGI3L_001772"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFG9197484.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(29656..31578)
                     /locus_tag="ACGI3L_001773"
     CDS             complement(29656..31578)
                     /locus_tag="ACGI3L_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9197485.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(31642..32490)
                     /locus_tag="ACGI3L_001774"
     CDS             complement(31642..32490)
                     /locus_tag="ACGI3L_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFG9197486.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            32903..33784
                     /locus_tag="ACGI3L_001775"
     CDS             32903..33784
                     /locus_tag="ACGI3L_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9197487.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(33992..34831)
                     /locus_tag="ACGI3L_001776"
     CDS             complement(33992..34831)
                     /locus_tag="ACGI3L_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HFG9197488.1"
                     /translation="MSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEYKYAVSQGD
                     YVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDELPLFLSRL
                     ECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARIVIESRDDV
                     SNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIADILCNPLS
                     RARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIVEPVGPWLE
                     KMR"
     gene            complement(35010..36944)
                     /locus_tag="ACGI3L_001777"
     CDS             complement(35010..36944)
                     /locus_tag="ACGI3L_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HFG9197489.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENVISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(37056..38069)
                     /gene="galE"
                     /locus_tag="ACGI3L_001778"
     CDS             complement(37056..38069)
                     /gene="galE"
                     /locus_tag="ACGI3L_001778"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFG9197490.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(38093..38968)
                     /gene="galU"
                     /locus_tag="ACGI3L_001779"
     CDS             complement(38093..38968)
                     /gene="galU"
                     /locus_tag="ACGI3L_001779"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFG9197491.1"
                     /translation="MQMTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIE
                     EAIESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHY
                     IRQKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGV
                     QKIAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSIL
                     EKQTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENL
                     KDDLMDYMRKKVSEK"
     gene            complement(39160..39480)
                     /locus_tag="ACGI3L_001780"
     CDS             complement(39160..39480)
                     /locus_tag="ACGI3L_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197492.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(39470..41461)
                     /locus_tag="ACGI3L_001781"
     CDS             complement(39470..41461)
                     /locus_tag="ACGI3L_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197493.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(41584..44127)
                     /locus_tag="ACGI3L_001782"
     CDS             complement(41584..44127)
                     /locus_tag="ACGI3L_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HFG9197494.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(44405..44739)
                     /gene="rnpB"
                     /locus_tag="ACGI3L_001783"
     ncRNA           complement(44405..44739)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACGI3L_001783"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            44871..45548
                     /gene="srtB"
                     /locus_tag="ACGI3L_001784"
     CDS             44871..45548
                     /gene="srtB"
                     /locus_tag="ACGI3L_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HFG9197495.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(45708..45782)
                     /locus_tag="ACGI3L_001785"
     tRNA            complement(45708..45782)
                     /locus_tag="ACGI3L_001785"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45748..45750),aa:Thr,seq:tgt)
BASE COUNT        15160 a         7870 c         5024 g        17773 t
ORIGIN      
        1 gtttagtatt tatactctta aagaaaaaat ccatcacaat ctgtccacct ttaaactgtg
       61 aatcatatga tttactcccc cccactgcaa tatacattcc tatccgtttc ttacttctat
      121 caattgaagg tttatttaat acatatttac ttgcatatat agcttgagtt ctatcaacaa
      181 cagtctttaa tttagctgat attgaatcaa aatgtacagg acttattact atagttcctt
      241 ttgaatcatc aaacatttta tataatggct tcatatcatc attaaacttg caataccctg
      301 ttttttcaca aaatccacat gctgtgcaat attcaatatc catattgtag atattaaata
      361 ttttacaact taatccacac tcttctagca tagcttttac ttcatttgct ataaaactgc
      421 aatttttatt aattcttgga cttccattta ttattataat ctctggactt ttaagtcctt
      481 ttttatcgtt tgaatccata atcaatctac ctatccttta acataactat taaaatatca
      541 tcatcataat tatcttttga tgagaagttc tttaaatcca attttagatt ttctactatt
      601 aactgttgat ttaatctaaa attttctttt agaaagtttt ctaatcggtt tataccatac
      661 tcttcttttg atgaattttt tatctctaaa attccatcag tgtacataca taccattgca
      721 taatcttcca ttgaaagagt attattttca taagtagcat cttccattat tccaataggt
      781 atgccctttt tacaatttaa attattttct attgtgccat ctttctttac aactacagga
      841 ctatagtgac ctgcattaga cacagtaatc atattttctt tagtatctat aatacctatc
      901 aaacaagttg taaatactcc catcttgtca aattcatcat ataacatcct atttaaattt
      961 gtcattattt ctcttggtgt attgtattga ttgcataata ctttaaaagc accttttatc
     1021 attgcaacaa cataatttga taccattcca tgtcccatta catcagcaac aatataaact
     1081 atatgttcgt catccacttt tgtagcataa taaaaatctc cacctactac ccttgctggt
     1141 ttatggtaaa aataaagttc tttctcatca ttacaatcca ttttaccttt atccataata
     1201 agctgttgtt gtttatttaa tatgttcaac tcgttttcaa gaactttgtg ttttacttcc
     1261 ttttcattat gttcatataa ttgcatacca acagaaactt gtttggacaa tatactaaga
     1321 atatttaaat catcactagt atagtttttg ctatttgcac aaactataca tcctatagta
     1381 tcatttttat cctgaagttt gtaatatata taactttcca aatttattcc cttttttgag
     1441 catggtttta aattatttag ataccccccc aatgactctt tctttaaaaa catatcaatc
     1501 ataggatata aatttgtttt ctttttttgc tcaacattat aacaactaac tatagcatcc
     1561 ttattatgat gactatttat aattattaaa gcttctttac tattagtaat attacacgct
     1621 tgtttactta aattttccaa aaagccatca atactcttat taaggtatag ttttttagta
     1681 gcttcattta tggcacttat tgagcctctt agtttatcaa ttaaaatttg tacattatta
     1741 tttttattag ttatttctat tgataaactt aagagtgatg caacagatga tataaaatct
     1801 atatcttgtt ctgttatata atcatcctct tttaaaaaac aagtcataaa tccaacaact
     1861 acgttattta ttataaaagg aaaaactatt ctcccaatat aaccttcagc ttttgctaaa
     1921 tctcgttcac cttctgctct agaatcttca aatacatttt ccacatatat tatctttttt
     1981 tcatttacag cctcatgtat atactctgga tatgtgtcaa aatcaatttt tgcaccttta
     2041 agactattta ttggaaaaat ttgaggtaca tattctaagg tttgcgaaca tactaagtag
     2101 gcatatttag aatcattttt ataaaataga ttcacacatg cctttgtagg gtgaacaact
     2161 tctaacattt tttctattat gtcatctttt atattaaaaa aatctgtaga ttcagtcacc
     2221 atagcggata tttccactaa attcttcatt ttataactgc cattagtcat actcaatttc
     2281 tccccctata tattaaacta tttattagta ttttaacata cattctttat agtaaaaaca
     2341 aaaacaacga caaaactagc aactaatatc cagttaaatc ctgtcaataa tcctataaga
     2401 agtaatgtaa ttaatgcatt tagacctgtt ctcccttttt catccataaa agttatttta
     2461 gagatgtcga tattattttt cacattattt atatgctctt tcacttgttc ttccatattt
     2521 cttttatata gtatataaac tacaccaact aaaaacactc ctatacctaa aaccatgttt
     2581 aaattaaaag ctaccataag caatattgaa ccaaaagcta actttaaaag cttaaaaaat
     2641 acactatcta tctttagagt tatatttctg atttctttac attcatctct taaagaatat
     2701 ccacttgaat ctaagttatt aatctttgtt tttacaattt cagaataaaa aagctttatt
     2761 atcccattta acattttcat cactcctaaa tattttacat atatttgtaa gttttacaat
     2821 tataatattt tttatacttg gtaataataa aaaataacaa atattttatt atttagtatt
     2881 tattgtaaat aagttattga agcttgatta gttaagtata gatttttaat aaatattttt
     2941 ataatttaga aggaagtggt tttgtgcaaa tagaacaact cgatttagaa acgagaaata
     3001 aaatatactg ctatactaaa aaaattctta gaaaatatca aaaaggcata acatctggaa
     3061 aattaacagc agataaattt gcagataata tattgtctca agattttatc agtagtatac
     3121 ttaatgaaaa aatagtcaat gagacaaact ttaagatatc ttatagaaac tatatagaaa
     3181 ctttaataaa tattcaaaat gaaaatttat ctaacttaag aaaaaaatct actaaaactg
     3241 caaaatgttt caatatctct caaataaccc aattaaaaaa cttactaagt aatactggtt
     3301 ataatttatt aattccatat aaatacttaa ctgctagaga tatagaagga atagttactc
     3361 ttattaatac tgggtctatt gaacttggaa atgagagaat ctacaattat atatcaaaag
     3421 tataataatt taaacctatt ataaaaaggc aatttattta ataaaaaata tttttaatat
     3481 taaataaatt gcctttttaa ttttggatta aatactgcta tccaagtgct ttttctagtt
     3541 tagataaatg ttgtattgga taatatttta gtagctcttt aaattgttct actgataaac
     3601 cttctgttgt tgtatatatt cttatttttt catctaagtc actattaata aatttgtttt
     3661 ttaaatcctc aaaatttaca ctactcattt tacatcactc cttatgtaac atattcattt
     3721 gtattatttt atccaaatac ataaaattta ttacataaaa atatatctat ttaataattt
     3781 aataaaaaaa agctatctca atttagaaat tactttctat atttgagata gctctagcta
     3841 aactaatagc caatagttat aaataattat ttataactat ctgttgcttt ttccagccat
     3901 ttgttgttca gccatttcaa ctaatttttt agtcatgtat ccacctacat aaccattttc
     3961 tcttgcagta aggtttcctt tatcaacttg ttgataatta ctcataccaa gttcattagc
     4021 tatttctaat ttcatttggt ttaaagcctc ttttgctcct ggtactactg ttctgttgtt
     4081 gttattgtta cttgccatgt tgattacctt ccttctgttt aatttatttt gtgttgctga
     4141 taatattatg tgattttaaa catttttaat tcaggtaatt tttagcaatt aaaacctgcc
     4201 aaatatccag tagaaaaagc tatttgcaaa ttgaatccac ctgtatatgc atctatatct
     4261 attacttctc cagcaaaaaa taaaccttct actaattttg attccattgt acttgaattt
     4321 atttcgttta cttttacacc accagaagtt attatagctt cttcaatagg tctgtatctc
     4381 tttactgtaa actttaaatt ttttaataaa tggactaagt tttttctctg ctctctagaa
     4441 atttggtgaa caaccgtatt tggattaatt tcacttaagt ttattattat aggtattagt
     4501 ttttttggaa gtaaatcatc taatgctttt tcaaattttt tatttgtata cttctgaaaa
     4561 tctttttgaa ctcttttatc caatttttcc tcatctaatg caggttttaa atctaataat
     4621 atagtgtaat tttctttcct tgtatctttc attctacaac ttgcagactt gattataggt
     4681 ccatctaaac caaatttagt aaattcaagt tctccaaaat cactataaac tttcttttgt
     4741 ttgctattaa acacccttat ttcaacattt ctcaatgata atttttctaa atcttttgta
     4801 aaactttctt gtacttctat accaattaaa gatggttttg tatctataat tgtgtgcccc
     4861 tgtgaaattg caaatttata tccatcacca gtagaaccag taagtggata acttaatcca
     4921 ccagttgcta ctacaactga atcacactta atttcttttt tatcgtttaa aattactttt
     4981 tcaattttat tatttttaga tattattttt tctactttcg aatttaataa tatatttact
     5041 ttcttacttt taagttgtct ttcaagagca tttacaatat caaatgcttt atcactctct
     5101 ggaaaaaccc tttttcctct ttctgtttta gtctttactc caagattatt aaacatactt
     5161 attacatcat catttgtaaa agtataaaaa gcactataaa gaaattttcc atttgtaggt
     5221 acattttcta ttaattcctc tatttcacaa gcgttagtaa tattacatct accttttcct
     5281 gttattgcaa gtttttttcc taatttatga tttttctcaa ttaatgttac atcatagcct
     5341 ttctcacatg cagttgatgc ggctatcatc cctgctggtc caccacctat tattactacc
     5401 ttcttcaaat aatcactctt ttctaccctt aattttttta atttaaacta ttgactctat
     5461 accttaaaat caatttaatt ttaaaagttt aaataatgct ggagctcctg ctattccata
     5521 aaaaacaact actgtattct taataaaatt cataaaaatt atactcatag tagagtcact
     5581 tatatttaaa gtgactatta acattgaaat aaacaactta atgccaatat ataacattcc
     5641 tattgttact atcccaacca aaaacctaca tattcttgaa aaaattatat ttttactccc
     5701 cttattttta ttgctaaaat ttattttttt gttattatta tctgtattaa atttaacaaa
     5761 tctatcctca accatatatc caaatacaaa tcctactatt ataccaaatt tttcaaaata
     5821 ttcagggcta tttagaaata tagccactat tataaatggt ataagtaaaa ctacaagtaa
     5881 aatataattt ttattatcat caatatagtc aaatattttt acaaatacaa ctgtaaaaaa
     5941 tattcctaat atccaacccg ctatcacatc tattggccaa tgaacagcta aatacagcct
     6001 agacaatcct actcctaaaa ccataactgc acctattaaa tgaagatatc tctttttaaa
     6061 tatagtcata atactaaccc aaaatgttgt tgcagtttga gtatgagcac ttggaaaaga
     6121 ataaccacca gcagtagaaa ctctcaatga ttcaagacct tttattccta ttggtctggg
     6181 agcttttaca aactctttga tgcctaaatt tacaacaaaa tttccaatta tagcaaacag
     6241 tattttctgt ccacattttt tatttataca ccagtatata attgttgtaa ttaatattaa
     6301 taacggtgct tctgtgctta ttgtaaagac aagaaatata aagttcaaaa ttggatttct
     6361 taaattttgg aaaaataata atatatttaa ctgaatatcc atatagatgt ctcctttact
     6421 aaaattttat ataattaact aaaaagcact aactccctta gaaattagtg cttttgattc
     6481 acatttaaat ctattctaca tcctcaacta tacctatata aggtaaattt ctatactttt
     6541 cagcatagtc tattccataa ccaacaataa atttgtcttc tataacaaat ccaacatagt
     6601 ctacaggtat attagctttt cttctctgag gtttatcaag tagagtacat agttttaaag
     6661 attttggatt tctagttttt aaagctgcaa ctagattact taatgttaaa ccagaatcta
     6721 ttatatcctc tacaatcaac acattctttc cttcaatatc tacatctaaa tcttttaata
     6781 ttttaactgt tccagaagac tctgttgagt ttccataact tgtaacactc ataaaatcta
     6841 tatttacatc caaatctata catcttatta aatctgaaac aaatacacta gctcctttaa
     6901 gtatacctac cactagtaaa tcttcgcctt taaagtcttc ttctatcttt tttcctaatt
     6961 cataaacttt ttcttttatt tgttcttctg tcaacatttt tcctgtaact ttgtacattt
     7021 tgtatcctcc cgctttcctt ctattaactt atatattata gcataccaaa atatcaatta
     7081 aaatcttttt catcattttt aaacctaaat taacagctta tccatacttt tttgcttttt
     7141 acattaaaaa tttggaataa cgattccttt gtattataat ctatatgtac atatattaat
     7201 cagttatttt tatcgattat ataattttat ttttggaggt acttttatga gcacaaacca
     7261 tggagctaat ttatatagtt tatctagtaa gtatggcttt tcaaaggaag aatttatgga
     7321 ttttagctca aatataaatc cttttggtac atcaagttta gccaaacaat acattgtaaa
     7381 caatatagat atggtatcta tgtatcctga ccctgattac atagacttaa aaacttctat
     7441 atccaattac tgcaaatgtt ctatagataa tatagtactt ggcagtggag ctacagaact
     7501 aatttcatca tttatacata caattaaccc taaacaggct cttttactct ctccagccta
     7561 ttcagagtat gaaaaagagt tatctaaaat taattgttct atagaaaaat actttgcaaa
     7621 agaagaagat aattttcata taaatttaga aaatcttata aaaactatca atgctaaaga
     7681 ttatgatttg gtagtaatct gtaatcctag taatccaact ggatttgcat ttactaaagt
     7741 agaagtgaga gaaattttaa aaaatacaga ctcattttta atgattgatg agacttatgt
     7801 agagtttact gatacagata catactcttg tactcaatta gttgatgatt attctaattt
     7861 attcgttata agaggtacat caaaattttt ttcaacgcct ggaataaggc ttggatatgg
     7921 tcttatatct aacactaatg tcaaaaatga aataaataaa aatctagatt tatggaatat
     7981 aaacataata gcttctaaaa tgggtgaaat catgtttagt gatttagatt ttatatcaaa
     8041 tactatttcc ttaatgaaca ctgaaagaga ttacctgctt aaagagctta agaatataaa
     8101 aagcttagat atatacaata ctaaaggtaa tttcatattg tgtaaaatca agacaaagga
     8161 attgactgct aaatctcttc gagagcaact gcttccacaa aaaataataa taagagattg
     8221 ttgttcattt gaaggtctag atgagtattt ctttagagta tgtatattaa aacctaatga
     8281 aaataaatta ttaatatcat ctcttaaagc aatttttaaa taaaaaaatc actttatttt
     8341 ataatttttt ataccataaa aaatgagcta tctctatttg agataactca tttttgatta
     8401 ttaaaaaact aagcactttg ctcttcttta tttccttttt tactcattcc atcatttatt
     8461 ttatctacta ctactgctat tgcattatct cctgatacat tacatgctgt accaaaactg
     8521 tcttgagtta agtataaagc tatcattaaa cttgcaagcc caccatctga tggtattcca
     8581 accattggta ggaaaggaag tgcactcatt atagccccac ctggtgctcc tggtgctgca
     8641 accattgcta tacctaacat tgcaatataa gggaataata cacctattcc atgtggcata
     8701 ccattcatca ttaaaactgc agttgtaaat cctgttattg atatcatact acctgataaa
     8761 tgtattgttg cacaaagagg tacaacaaat tctcttattt gcttacttac tccatttttt
     8821 tctgcacaac caacattaac tggtatagtt gctgctgaag attgagttcc tatagctgtt
     8881 aaatatccag gtacttgatt ttttaacatt cttactggat tttttcctga aaatacacct
     8941 gctgctgtga attgacatgc catatataca aaatgtaaag gtattactac taagtatact
     9001 ttccagaata cccctaatat tgtccatact tcccctgcta tagttatatt tgcaaaagtt
     9061 cctgctatgt ataaaggtaa taaaggtata atcactgttg acaacgtttt cgttacgatt
     9121 ccttgaaatt cttggaagaa attaaataaa gtctctcctt ttccatgatt tcttaaagct
     9181 gatattccaa gtcccattac aaatgcaaat acgattgcag ctgttacatc taccataggc
     9241 tctaatggaa ttgtgaatat tggagctaac attcctgcct ctgggtctcc aatttgactt
     9301 gcaacacttg catcaataaa atttgggaag attaatgtag atactgcaaa tgataataat
     9361 cctgctatta aggtagaacc atatgctatt cccgtagtta tccccaataa ctttcctgca
     9421 cctgttgcta aatcagctat acctgctgtt acaaaaccta taattataaa tggtataaca
     9481 aattttagga atgctgagaa taaagtacta actgttacta atatttgtac tattatttct
     9541 ggtgcataac ttccgattaa aataccgact atgataccga tgattagttt gggcactaaa
     9601 cctatttttt tcttcataat atttaccctc cataactttt ttaaattaag cattcttgca
     9661 cattgaatac ttagttaaat attggatatc cacttattat gataatagag ttttacctct
     9721 ccgtcaacaa tttaaccatt ttttgttaat aaaaaaaaga ataacatata taaattgtta
     9781 ttcttcttca tcttttatag aaaattctac attttcaatt atatttgaat gtttatcttt
     9841 ttttgcgata actctatact tattaatttc ttcattcact atacctatac tccaaattaa
     9901 aactatagca tcatctataa aaccaaatgc ccctgcaatc atctctggaa ttatatcaac
     9961 cccagataca aagtaggata tagtaaaaat taatacagaa attaccttta ttttatcaac
    10021 tatattgatt cttttatctg tcataaaatc aggtagttta agtaaatcaa atacaaaaac
    10081 caaaccaaat ttagcatttt taaatctgac caaaattttt tttaaaatat ctaaaactat
    10141 attaatgatt atttttaaaa actccatatt tatcacctct tataattata ggttattcta
    10201 cattataacc gatataatta atttgatgaa catattagat ataaatttta tcaattagtt
    10261 tatatttaaa ttataataat tcaattcctg cactactaca attttgaatc atatcctgtg
    10321 gccatactcc aacttgtact tctcctatat gagctttttg taagaaatac atacatattc
    10381 ttgactgacc aattcctcca ccaattgtat acggaagttc gccatttaaa agcatcttat
    10441 gatagtcaaa ctcttttctc tcttcacatc cagcaagttt caattgtcta tcaagagatt
    10501 cttcatcaac tctaattccc attgaagata attctaatgc tgaatctaaa acaggattgt
    10561 aaaataatat atccccattc aattcccaat catcataatc aggacttctt ccatcatgtt
    10621 tttctcctga tattaatgtt tttcctattt gagttataaa tactgctttc ttctctttta
    10681 caattttatc ttctctttcc tttggtgata attctggata catatcttct aactcttgtg
    10741 atgttataaa agttatttct tctggtaata tttcttttat accttcatac atactacata
    10801 caaaaatttc agtatcttta aatactccat acaatctttt tacaacatct tttagagtct
    10861 tttcatttct actactttta tctataacca attcccaatc ccattggtct acataaagag
    10921 aatgtatatt gtctaattct tcattttttc ttattgcatt catatctgta tataaaccac
    10981 taccaacttc aaacccatat tttttaaggg ctaatctttt ccattttgca agtgattgaa
    11041 caatttctgc atttttattc ataaatggta tatcaaagct tacagccttt tctccattta
    11101 aattatcatt tgcacctgtt tctggcaata caaataacgg agaagaaact cttataagat
    11161 ttaattcatt acttagtctc atttcaaaaa aatcttttaa tttttttata gctatttgtg
    11221 tatcaattac gttcaaacta cttttataat cctttggtat tattgtgctc atatcattca
    11281 ctccctatat ttatatattt ttccattaaa aaaacccttc atccctatat aaaagggacg
    11341 aaaggttgct tttccgcggt accaccctga ttagtttgaa ataaattcaa acccagctca
    11401 caatgtacag atattactcg atacacccca atatgataac ggtttggttc cgactaagcc
    11461 tactctttta aaatttcggt tagcaactcc aggatgttct tcactataga cttcatattg
    11521 gtctcacacc atcaccaact cgctttaatt acattctata actactcttc ctttcaaagt
    11581 ctttaagagt ttaattcaat aaaatttagc tctcttatgt tttctattta ttcataatag
    11641 tatgataagt gattagttaa aatttgtcaa gtttattatt tttttatttt taaacacttt
    11701 ataaattttt acctatactt tataaatttt caaatatagt ctttaatctg tccatacatt
    11761 cttttaataa agactgtgga caagctacat ttattctttc aaatcctatt ccttcttttc
    11821 caaatatata accttcatca aataatacat tagctttttt aaacattaaa tcttcaagtt
    11881 ctacttcatt taatccataa gcagtaaaat ctaaccatgc tagatatgtt ccttctggat
    11941 aaacaagttt tacttttggt aggttttctt ttaagtattc atcaataaat tgtatattat
    12001 tatctaagta atcatttaat tcattaagcc agtcttcact ttcattatat gctgctattg
    12061 tagctacaat agcaaaggga tttggtgaag ttgcaactcc aacagctgta acctcttctt
    12121 gatatttctt ttttagttca tcattattca ctattatatt agacaactgc attcctgcca
    12181 gattaaatgt tttacttgga gctatacatg taactatttt atccttgtac tctgggcata
    12241 atgactgtaa aggagtatgt ttaaatcctt ttctaattaa atcagaatgt atctcatcag
    12301 ctattatcca taggtcatat tttttacata tttctacaac cttttttaat tcatcttctc
    12361 tccaaactct tccaacaggg ttgtgaggac tacaaagtat tagtacttta ttgttgctac
    12421 acttagcttt ttcttctaaa tcatcataat ccatcctata agtaccattc tcatatatca
    12481 gaggattgtt tacaacgtcc ctattattgc tctttatctt agcttcaaat gggtaataca
    12541 ctggtttttg gactattaca ccttcattag aattagttaa tattcttact aaaatagcaa
    12601 cagcaggtac aacaccagga ctaaaaataa tatcttttct acttatttcc cagttaaatc
    12661 tccttttata ccaatcacaa actgcattaa agtatttatc actatcattt gaactatatc
    12721 caaatatttt atgttcaact tttttacgta atgcttctat tattggttct gcacattcaa
    12781 aatccatatc agcaatccaa aaaggcaaac catctttttg tgcttttgtt gaacaattag
    12841 ttctaaaatc ccattttaca caatctgttc ctactctatc tattactctg tcaaaattat
    12901 acttactcat tttttccctc ctaagaataa aatttttata attgttaagt ctattactag
    12961 atgcactttg gtattatttt acaattctta atattataat aatatcactt ttttgtccaa
    13021 tagatttaaa atataattac ttttccatca tattttttca atattccaaa atcagtttca
    13081 ttatatcaaa ataagattgc tcatattaat tattttctaa ttaacataag caatcttttt
    13141 ctataacttc tataattata attttaaatg tagaattatt agtttggatg ttatcccaat
    13201 ctcttttcaa ccaatctaca ccatatatct acaccatatt ctaaagcttt cgtatcaaat
    13261 gttacatttg gattatgaaa tcctggtgta gcatcagctc ctaatccaat atatgtagtt
    13321 ttacatttta gtttttgtgt ataataatgg aagtcttctc caccagaatt tttaaatata
    13381 cctatagatg catcagctcc caatacatct tttatagttt cttcagccaa gtttacaagt
    13441 tcttcatcaa attctgctgc tggtactcca tctttggaaa ttagtacagc ttctgcattt
    13501 atagaactta caacagtttt tacagcatgt attgcttttt cttttaattc ttctattata
    13561 tcattacttt ctgcccttat atctaaagcc ataaatgctt catctggtat attattataa
    13621 gtttctccct taactgatat atttgttact tttatagaat ttggtatagc tggatttact
    13681 cttattgcat ttattgcatt cactgctaaa cagacagcat ctactgcatt tactcctaaa
    13741 tgtggtttag aaccatgaca agtgatacct ttaatcgtaa attccattat acagctagca
    13801 caatggtaca ttgcaggtat cgcctttccc aacctacaat cttgtccagg tcttaaatgc
    13861 atccctacca tttcttctac atcatccaac aaaccagaat caattactct taatgctcca
    13921 tataattttt cttcacctgg ttgaaaaagt atttttaact tacctctttt tactaaattt
    13981 ctctctttta ttaactttgc agctgttaaa agcatagaag tatgaccatc atgaccacaa
    14041 gcatgtatca ttttcttttc tccatctatg ataaattcca atgcatccat atctgctctt
    14101 atagcaaata ctggtccttc ttttttagaa tctatagtta ctataatacc agttcctgca
    14161 actcctttat taatattttc aaaccccatt ttttcaagct cttttaaaac aaactctgat
    14221 gtcttatatt cttcaaatcc tttttctggt atagtgtgta gataatcata cactttatgt
    14281 acatactcaa tataatcttt gttagttccc ataatctagc tcctccttaa aatttaaact
    14341 ttccatttat attaaatttt tattataatt acctatacta cgaaataatt cattataagc
    14401 attgcaatac aaccatttaa agttgctata acaaacatat gtggataata tttagttttt
    14461 aactcagctg ttcctaaaag tctccccata aattgtatct gcgctcctga aagcaataac
    14521 attggcaata gaattgcaac atgtgcttga cttatttgac ctgctgtaaa taaacctgcg
    14581 attactccag atgctcctcc cattgatata aatattgtca ttatagctgt tgctgcaaca
    14641 cctggaagtc caaagatact cattacaggt gtaaatattg tccctattac atccaaaaga
    14701 cctgttaagt tgaacacaga aattatagca aaaccgaaga tgacatttgg agccattgaa
    14761 tttgtactta tttggaatcc atttctagct cctccaataa acgcatctat cacatttcct
    14821 tttttaactt ttacttcttt ttttgctacc tcactcatgt taagcttccc ccttgtcaaa
    14881 tttatttaaa tataatctaa gtaagttcgc cccaacaaac ttcataatta atattaaagc
    14941 aagtggtata aatattggta catctcctat aaatggaaat agtgctgctc cagaagcaaa
    15001 gaaattcgta attgcagacg cacctgaaaa ttgaaatgca caaaatacag ctttttgttt
    15061 ttcatctata tacccatcat ctttaagttc tttagtcata gatgcagctg catctgtaga
    15121 ctgtaaacta gctatcaaag ttagtcctgc aaatccaggt aaccctaata atggctttaa
    15181 tagtggacta agaagctttt gagctgcctt cattccatct aagtggtcta taactctaac
    15241 tactccaagt gcaaacataa ctgatggtat taatgtcaat gcatatagcc atccatctcg
    15301 agggccagta cctccatcac ctctaaagtt tgcagctaat gtacctacac catcattaat
    15361 tgttcccaat gttccaaaag aacctaatac attgttaaaa tccaatactt ttaatggtcc
    15421 tggtgcatct ttaaatattc ctgaaaaaaa taatgctccc aatattaatg ctacataccc
    15481 ataccatttt acctcaactt tttctgttgt tgattctaat ttactcatat aaattctccc
    15541 tcctgtttaa atgaatttta ttagtatact tgtttaataa gcaaaactta tgccaatacc
    15601 ttaatgataa agcctttgta tttatttttt tattgtaaat ttattccagt gattaaatag
    15661 cttataatta cttacttttc aagtttaaaa atataatatt tttttattaa ttatttaaaa
    15721 tatacattac aatataaaaa gctattttcc ttatcttgca aaaataattt caaaataggt
    15781 ttttatagga taaaatccta aaaaaaccta ttatttaatc aaatatataa atttatacta
    15841 ctatttgttg tataatataa cttgccttat actttaaata ctttaaaaat aaatactatt
    15901 ttgttaggag aaataaaatg gataaaaaga agttaatcct tataacatat gataaattga
    15961 atagtgacca ctacaaagaa gaattaacaa acttttttgg agacgaaata atcatagaaa
    16021 cacaaaatat acttgatgga ataaaagaaa atttagaggg agatgtagtg ctttctctat
    16081 cacctttaac tagtaatttt ttaataaaac attttaagga agatattgaa attattcatg
    16141 gaacgaaagc actttcaaaa cttggatatg aaaaaatgat gaaactgcct ccaggtacaa
    16201 aatcgttact tatgacaacc aataaaactt cagcatttga gatggctact tatctatata
    16261 aaattggtat aaatcatata gattttgtac cgacatatcc agattgtgat gaaatatatg
    16321 atttagatac agctataaca ccaggtcaga ttagatttat accaaaatac ataaaaaata
    16381 ttgttgattt aggttggaga aaaatctcat tagatacata tatgtcatta ttagtagtat
    16441 taaaactaaa aaatgagaaa tttatagaaa aattatacaa attgtccaag gagacactaa
    16501 gtcatgattt cttaaataca tcattagata atatatctaa attaaaaact atactttaca
    16561 tgaccattga tgaaataggt gatggtctaa tatttttcaa tacctttaat aaggttactt
    16621 ttgtaaataa gtctttactt aatatgttgg aactagatga aaaacttata aaatcacctt
    16681 ccttaatgga atatatgcca aagagtttct tagataaaat tacaaagaac ttaaatatag
    16741 ataatatgat tatatacata gacgaaatag ataaaaaatt catactttct aaaaaaccat
    16801 tttatcttta taaaaatata gagggttgct taattacatt aaaagatgta aacaatatag
    16861 aaatattaga acaaaaaata agaagtgatt ctgtcaaaag aggttatgta gctaaatata
    16921 aatttaataa tattattgga aatagttcta ttataaaaga ttgtattaaa aaggcaaaaa
    16981 aaatggctct tacagataat cctatattaa taacaggtga aacaggaaca ggtaaagaag
    17041 cctttactca gtcaatacac aatcattcaa atagaaaaaa taaacctttt gtagcaataa
    17101 attgtgcttc attaccaagt gaattacttg aaagtgaact atttggatat gaagatggtt
    17161 cttttactgg agcaaaaaaa ggtggaaaaa aaggattatt cgaattagct catactggca
    17221 ctatattttt agatgagata ggagatatgc cacatgattt acaggttaaa cttttaagag
    17281 tcttacaaga aaaagaaatt agaaaaattg gtggtacaag tattattcca attgatgtga
    17341 gaatattagc tgccacaaat aaagatttag agaaattaat tatagaaaat aaatttagga
    17401 tggatttatt ttataggata agtatgttca ctttagattt acctcctctt agaaagagat
    17461 tagaagatat acctcttctt ttagaatcat ttttaaaaga acttccctat aaaaacataa
    17521 aactcgataa gagtctttta gaagctttaa attcatacac ttggatgggg aatattagag
    17581 aactgagaaa ttgtgttgaa tatatggctt acatgggttc caattatctt acaataaatg
    17641 atttacctca aaacatatct tcaaaattaa ataataatca tatgtcaagt aatatgtcca
    17701 tattcaatga tttaaaccaa tatgacaaaa acatatgcat ttctatccta aaatcattgc
    17761 acatgaaacc aatggggagg acaaagttaa tgaaatttat ggaatataat gtcacagaat
    17821 acgaagtaag aaatatgcta gaatatttga cacgcaatgg atacttaatt tctagtaagg
    17881 gaagaaaagg ctcatcaata actgagaaag gcataaaaat aatagaaaat aatataattt
    17941 aaacctatag taattcatct ttactttatc aaaatttata tataattata attttttatt
    18001 tttctataaa ttttttataa aataataaaa cttatttata ttaaaaacga agctatctca
    18061 acatatggat aagcttcttt ttaattgtta aaaagataaa aatatatttg atttaacaga
    18121 aaaagagtgc ctcataaact aaaaagttca ttttgagaca cgtccttaat attaataaat
    18181 taattggctt aaaattactg attgataatt ataaagtacc tctgttaaag gagtaaattc
    18241 tgaaccgatt ccaaatctta attctgtaaa cgcctctaaa taatctgggt cacatacatc
    18301 ttcttgtgtt aaatcttgtt tcaccatttc agtagcaaga taaattgcta ctgatggtag
    18361 aaaagcatcc attggcatag gatatccacc aagtctattt gacatgccaa aagccttagc
    18421 cttttcactt atcatgtcgt ttattttatc ataattttga gcatcttttt cagatatttt
    18481 tagacccata acactaggat atgtttgtat tggtgatgga ttgctttgct ctgcaactat
    18541 atactttaat tctaaagcct tagtcaatat aacttcatcc atatactcat ttacaccaaa
    18601 tacatttata tcttttccat attttttaac ttgtttttca atatcttcat ttaaaaactg
    18661 cttaactttg tttttgtctt cttcagtatt tatatttgga gtattaactt gtacaaatgg
    18721 caatcctata tttttgcaag tctctttaat catttctaat cttttggcta tattaacatc
    18781 tttcaaatca tctgtagagg cataatgaat aaaagctttt gctcccattt cttttgaacg
    18841 ttcagctaat acttttcctc tttcctctgc actaacccct agattcacat caacaaattg
    18901 gcttaattgg tttttatcat ctcccatagg ggcagaaata gttattattt ctggacgctt
    18961 ttcctttacc ttttgtaaag caggtaaaag ccctgcttgg tcagttgaaa ctacaatagc
    19021 ctgaacttct ttatcgtcag ccaactttac tatcttatta atagcactgt ctatattaga
    19081 agtaaaattc tctggcaata caacatgctt tatagtttgt ttaactttag tttgaccatc
    19141 tttgtcttta tcaattttat tctcttcctc atattctttt gccatctctt ccaccatatt
    19201 gtattgtact ttattttcag ataatggttg agttaccact gcaactttaa aatcatctat
    19261 aattttctct ttatctttct tgcctacaag taaactacaa cctgtaagtc caataattaa
    19321 acatatggat agcataaatg ctgttatttt tctaagcatt aattaaaacc tcctaaattt
    19381 gtacattctt atcactatta ctaattttat catacttcaa agaaaaatta tattataaaa
    19441 aattatatac atgctattat aatccaatct aaaaagtact atgggtagat taggtttaga
    19501 ttaaacctac ccatagtact aaaaattaat atattataaa attaaattaa ttacaaatta
    19561 ttatgctact tgtttgttgc tttttataaa gttaccaact attccaccca atatagctgg
    19621 tattacccag ttaaagccca aacctgcaag tggcaagctt tgtataaatg gaacagctcc
    19681 tgtcattcca tttatagctg ataataaact aatcactaat gtaacatatg ctgcaccttt
    19741 aaaagcatta tcattcttta tatgtttacc agccaactcc ataacaacta ttgctaataa
    19801 aacaggatat atagtttgta ggattggaac tgatatggct attatagaat caacacctaa
    19861 atttgatata agcatactag ctacacatat acctataacc agttgtttat aactcgcctt
    19921 acttattcct tcaaaataag ttgatattga tgctgttaaa cctgtagaag tagtcagaca
    19981 ggcaagtgcc acaattacac ctaaaattac ctttcctact tgaccatata acaatatact
    20041 agttatttca actaataaag atgcttgagg tatactagta tcatataaag ttgaaactgt
    20101 tgcacctaaa taagtaagac caccatatac tactgctaga aatacacagg ctacaaaacc
    20161 agctttaata gtcattccta tttggtcttt atctgatgta tatcctttag ctattataga
    20221 catcaacatt atagttgcca tagatgctgc acctagagcg tccattgttt gataaccttg
    20281 tgatatacct tcaccaaata gatttttatc tatcatatgc tcaggactca taggtcctgc
    20341 tggagaaatt atacccttta ctattaaaac aaataatact aataataacg ctggagttaa
    20401 atacttacct attatgtcta taaccttaga agacctaata gtaaatgcta aagttagccc
    20461 aaagaagatt attgaaaata cagctttagc tactggacca tggtctccaa atataggcat
    20521 aatacccatt tcatatgttg ttgcgcaagt tcttggtatt acaagaagtg ctaaacatgc
    20581 tagagcagct acactcatta ctcttgctaa ccctttacca gctctcctaa gtacatcatc
    20641 catgcttccc ttacatcttg ctgttgctat aataacaagc attgctatac cagcatctgc
    20701 aacaacaaat ccaataagag gaattaacca gtctttgccg gattccatcc ctaaaaatgg
    20761 aggaaacata agatttcctg caccaaagaa catagaaaat aaagcaaaac caactataaa
    20821 aatatctctc atctgcttac tcacactaaa ttaccccctt tgaaaatatt ttgaatatta
    20881 agataatctt actttatttt cagaaaaatg tcaatctggt aaaaattcac acattgttaa
    20941 cgttttccca atttatttta tgaatatttt tttcatttta tgataattcc catcaatttc
    21001 gttaaatcaa ttgcttgtga cacatcaaaa attgctcctc taatatcatc tataccaatc
    21061 tcaattccct caatattatt agtagtaaaa tctatgccag aaagtttagt tccattaaag
    21121 tttgcttttt ttaaatttgt atactcaaat actagattgt caccttttac ttcttgaaat
    21181 acagaatttt caaaatttga atctaagata gaaactatct taaatttaga gaatgaaaag
    21241 ttagaatact tacctaaaac atccttgaac aaaacgtttt taagtataca atcatcaaat
    21301 ctaactccta tcaatttact atttttaaat tcaactctgt atatacttcc tccatcaaaa
    21361 aatgtatttg ataaattgca gttttcaaat accacatcaa gtaaatcaat cttttttaaa
    21421 ttacaatttt caaaagacac atttctaaat atacaagatt caaagctaac tcttacagaa
    21481 tctaaatcac ttataacttc attttctata attttattaa atattttttc atcattaaat
    21541 atatcttcaa gtatatcttc aagattttca ataatttcta attctcctgt aaatttaggt
    21601 ttttgcactt taataatttt agtcattttc ccctccacta taaattatat tatttttgat
    21661 attatttttt ttaatatatt aacttaatat acatatttga tatattaaaa agtttttacg
    21721 aaatatccat gtattcagta cttttataat tatatcacaa actcatttat aataaacttc
    21781 cattaatagt ataaaacaag ttagaataat tgacattata ctcatacata ttcaattatt
    21841 ggaaaaagta atttttttca ataaataacc ttaatttttt ataaaatcga caaaaaaacg
    21901 aataatttta ttatatttat tgtaaataat acaatattac gatataatac aacagaaaaa
    21961 caaatagaaa atgttcatat aatattagta atacggtcta atagtttcta caaactcacc
    22021 ttaaatgggt tttctatgaa tagaatgtca actctgaata tatgttctat tctatctata
    22081 tgaatatata tttttttgtt tatatcttaa agttttttgg aggtaaaaat ggtaccaaac
    22141 actaacaatg tacaaccagg tggaaataat tcatcattaa gctttttaga caaaatgttt
    22201 aaatttagcg aacgtggctc tagccttaaa acagaagtaa taggtggagt tactacattc
    22261 ttaacaatgg catacatagt tttcgtaaat ccagcaatat tatctgaagc tggaatggat
    22321 aaagccgccc ttataacagt taccatacta gctacagcca ttggtacact tatatttgcg
    22381 attttaggaa atgcaccatt tgctctagct cctggtatgg gattaaatgc atttttcaca
    22441 tactctttgg ttataggtgc aggaatccca tggcaaacag gtcttggggt agtttttcta
    22501 tctggatgtg tcttctttac actcgcagta acaggtcttc gaaagacaat tgcagacgca
    22561 attcctagag aattggcagt agcatcttca gcaggtatag gtcttttcct tgcttttgtt
    22621 ggtttaaaaa atatgggtgt tataatagct aatccagata ctatagtttc acttgcagat
    22681 tttacaccaa cagttttaat agcccttttt gctcttatct taatggcaat actagaatat
    22741 aaaaaagtta aaggtggaat attgataagt atagtagttg caacaataat atctgttata
    22801 tttggatttg tggagttgcc aacagcaata atctcaacac ctcctagtat agcaccagtt
    22861 gcttttaaat tagatattgt aggtgcattg aaattctcat taattggacc tatattctct
    22921 ttcatgttta tagacatgtt tgattcatta gcatttctta ttacttgttg taaacaaatg
    22981 ggtcttgaag atgagaatgg tgaaataaaa gatttaggaa gaatgttata tgcagatgtt
    23041 tcttctactt taataggctc attcttagga actagtactg ttacaacatt tggagaatct
    23101 gcttctggta ttgcagcagg tgcaagaaca ggacttgctt caatagtaac agcagcatta
    23161 ttcttagcta cacttatatt tacaccatta cttggtatag ttcctactta cgctgcagct
    23221 cctgcacttg taatggttgg tgtgtttatg tttgaaagca taaaacagat tgattttgct
    23281 gatagcaaaa tagctgtacc tgcttttgtt acagttttat tgatgccttt aacttatagt
    23341 ataagtattg gtttatgctt tggatttatt tcatatataa taatgcatgt agtagctaaa
    23401 gaaactgata aaatcagtat tacactttgg attataggtt tacttgcagt tgtaaactta
    23461 gttctaagtt aatattttta aatagttcta ggtcaatatt ttaaattata tagaataaaa
    23521 tcttatttat tttaaattta taaatagcaa aatcacttta tatgtaaatt gattttgcta
    23581 ttaactttgt atagaaaatt tattatcata atatatagat ataaaaatat atagaaaagg
    23641 agtggtgttt atgtcacaat tacttataaa aaatgcatat ctaattacta tgaatgcaga
    23701 tagagaggta tatgaaaatg gaagcatact tattgaaaat aatattataa aagaggttgg
    23761 taagtttgat attaatattg tagataaaga tgcagagata tatgatgcta aaggaaaaat
    23821 actaatgcca gggctagtca atactcatgt tcacttatct caacaattag gacgtggtct
    23881 tgcagatgat gttgtacttt taacttggct tagagaaaga atttggccat acgaaagtag
    23941 cttcaattat gaagattcct tgatttcatc tactgcatgt tgtgttgaat tgataaaatc
    24001 tggtgtcact acatttttag aatctggtgg tcaatatgta gatgctatgg ttgaagctgt
    24061 tgataaaact ggacttagag cctgtttagc taaatcagtt atggatacag gagatggtct
    24121 tcctgaggca tggcaaaaaa ctactgatga ggaaatcaac actcaattag acttattcca
    24181 taagtttaat aatacatcta atgagagaat taaaatatgg tttgcattaa gaactatttt
    24241 taatacaact gaagaattac ttgttagaac taaagaacta gctgataaat acaatacagg
    24301 tatacatatg catattgctg aaatagctga tgaaatttca tttgtaaagc aaaacaatgg
    24361 agttggaaca gttgaatacc ttgataaact aggtgtatta ggaccaaatc ttttagctgc
    24421 tcatacagtt tggcttactc ataaggaaat tgatttattt agattacatg atgtaaaagt
    24481 ttctcatgac ccaggttcag ctatgaaagt ggttctaggg tttgcatcaa ttcctgaaat
    24541 gttagaaaaa ggaatacctg tttcaattgg tactgatgga gctccttcaa ataatagaat
    24601 ggaccttatg agggacatgt atcttacatc actaatacat aaaggaagaa ctttaaaccc
    24661 aactgtcgta ccagctgaag aagtcttaga aatggctact ataaatggag caaaatgtgc
    24721 tttactagaa aaagaaattg gtagtcttga agtaggaaaa aaagctgata tgattattct
    24781 aaatccagat acaattcatt gtttaccaat gcataatcca attggaaata tagtttattc
    24841 tatgactagt gaaaatgtag actctactat ttgtgatggt aaatggttga tgaaggaaag
    24901 aaaagtatta gttgtagatg aatctgaatt attaaataaa gttaaaaaac aagcttctaa
    24961 aataaaagat aaagcagaag ttaaaattcc atctaaattt aaaattataa aataacataa
    25021 atttcaattg ttttgtaaat atgaatatat aaatatattt atatacatca tatatacaaa
    25081 acaattgttt ttttatttta tattcattag cattgctcat aaaatacacc ataattccag
    25141 aaaaaataac caatcagtta ggattacatc atctaagcaa tatataaacg tcttagttta
    25201 taagttttat tctactctta tctaaaacca tctttaaaga gttttcaact gtttcaatta
    25261 catctttata actcaagtac acatttgcgt agatacaatc ttcatataaa ttatattcag
    25321 ttactctaca atacagcagt tttcctccat ctaataaatt gctcaaaata tagttttctt
    25381 ttcttgggac atagcctatc acatatccag tttcaccaac tattttaata gctttttcat
    25441 catatagatt atctttctct ctagttaaat agtatatctt acttttctcc aattcttttt
    25501 caagatattc tctatttcta aaccttgaac cagcaacagc tattgaagtc aaatagatat
    25561 ccttaccatg ttcatctact tttatttttt caatatttac aaattctttt tttaaattat
    25621 tactttcata taatactctt cttaattcat ccttcaatat aacatttttt tctttttcat
    25681 acgcttcttt aacaattttt aattcttcaa gagatagttt ctctctgtat ctttttaaga
    25741 tatttatgga ttcttttctt acttcattta tatttccaaa tattcctttt aaagatatat
    25801 tctttccttc aggatatagt gatttacttc ctttaagcac aataaaaaat aacatatcat
    25861 cataatattc ttgagtcaat ttatcttttt ctatatcttt catttttcca attaaatcat
    25921 ctattttaaa cgtctcttca aaaaaattta ataattttaa tctagaactt gtcgttccct
    25981 ttttagatat atgccaatat acctcaaaat ctctaatatc tctatttaga tatggcaaca
    26041 agtcatcaaa agataagttt acatcataaa tttctgacat ttttataata tcttctgttt
    26101 ttccactagc atctcttaat gcttcaaaat atatattttt ccatttttca ctgagcaaga
    26161 taccatttat ttctttttca aattcaatct tattgcactc tatattttca tcttttaaga
    26221 cgtttatagc tattaggaaa attgaatata aactttcaaa gttagtccca taatttacta
    26281 cagtaggtaa aaatcgattc actaattcta atttattacc tatatattta aattctacac
    26341 ttagcaagta attgcatata agacgtgcta aattatttat cttttcttta tctaaatctc
    26401 gtttttcaag atattcattc aaatctacaa ttgaaataat atagttcatc aataatcgtt
    26461 cgtactttgt atccttataa ccatcttcaa ttagatagga atttatttta gaatctaaat
    26521 tttccatatt aacaatagca aatactttta ttgaacctgt agccttttta gataaattaa
    26581 ataaatatgt attgtaaaat tcaagttttt taatagtatt actcagataa aatacgtatt
    26641 ctccagattt agaaaatgta tctacaactt ctcttaagtt ttctacattt agatatttct
    26701 cacttaaaac taaccctagt tttacatact caactttttt actcttatat attaattctt
    26761 tagttaattt atataaccat ttctcatcaa taatcatttc ttttaccaaa gtatttatct
    26821 ttttcataaa aatttcgaaa taacaaatta aagacttaga attactaccc tccaataaat
    26881 aaatttcatt agattcactt ttatacatat ttaaaatttc atctactaga ttatttgcaa
    26941 gctctacttg ttctcttaac ggtatacttt catatataca taggtaattc atttcaaatg
    27001 attctttgta tccatcataa ccattaaatt cctgcaatcg cttaaaaaca ttctccacca
    27061 aattatcctc ctttacatga tgtaatttat attgattata ctacttattt catcaagttt
    27121 acatttatac gcaaaaaaat attactagaa attgaaattc tagtaatatc cttattatta
    27181 attatgtaaa taccctatct tataactgta aataatatcc ttattaattt taattacttt
    27241 taataaaaat ctatcctaga tttagacttc tctatgcata tattatacta atattagaca
    27301 tcataatcat acactttttc tttttcatat ctcatgttta caaacaatgc aagtaaaatt
    27361 ccaacaaatg ttattgccac attaaacaat acaacatatt ttggtccatt aactccccct
    27421 gattttgtaa taatacctgc tatatttaaa ataacatagt ttgctatact agatgcaatc
    27481 ataactatag atgttatttt tcctttatta gttggaaaca tttcatttgc agttgacgtt
    27541 gttaactgaa gaacacctcc tgctgctgaa taacctatta caaatccccc taacatacaa
    27601 atagttggag tttgaacaaa atatacaact aatagcataa gtaaagctat tataggatat
    27661 ataactaata ttcttattgg tttaatatat tttttaataa gtaaagaagt tattaatact
    27721 gcacatatta ctcccattga gtaaaaggat tgaatttttg tagggtcagc catcccatac
    27781 aatttaccca attcctgatt acaatttaac cataatacaa atgtagatgt acatgtaaat
    27841 ccaatacaaa caagagctat acttgttggt gtaaatttca tcttctctga tttaactgtt
    27901 ttgcctttgt tatcaataac attattagct ggtggaaatg gtaacacagc tatcaaaaag
    27961 gcatctacta caataagaat cgctgttact ataaaaataa ctttaaatga tattgaattt
    28021 gctgcaacaa atccaattat aaaaggaagc aaaaattgtg ctaaagctat tgtaaattta
    28081 gtaaacatat ttgctattgt tcctaaacta gcaaatatct ccatacaaga aggagttaca
    28141 caggtatcta agaatgaatt tgctgcccct ccaattattg caaatacata tgctatataa
    28201 aaatttggtg aaaatacaat tccaacaaag aaaattgcat gtagaaagtt tcctataaga
    28261 ccacttactt ttcttccata cttatctgaa ataggtcctg caaatggata agatataagt
    28321 ctccctaatc ctagtgcagc aataacagct aaaacaatac ttacatccaa tgttccatct
    28381 gataatgttt tagcccccca cattgatgaa aattctggtt tgtattgtcc taaaattgaa
    28441 attccaatac caagtaaaaa atatgaaaaa tacaacgcta tggcagtagg ataatatttt
    28501 ttattgttca taatttttct cccattcttg ttaatttatt aacatttttg tgtacaataa
    28561 actcatcccc ataatggatt taaagtatag tcagttaaag cttcaaattt aactggacta
    28621 tgaggcaaaa cccactatga caatttgtaa tttattatta aaaatattga aatacgtatg
    28681 ttttttcatt gtttaagata ttactcttat ctatttaaag cataattcat taacttcttc
    28741 tacaggcatt tctaatccag tatatagatt aaaagcttct gctccttggt ataataacat
    28801 tcctaatcca ccaatagcct tacatccatt agcttcagca tcttcaatca tttttgtttt
    28861 cttaggatta taaacgacat ctgttactac taaatctttt cttaaaacac tagtatcttt
    28921 tatatttgtt tcattgtcat aaggcttcat accaataaga gttgcatttg tcaatatatc
    28981 acttgattgt atctcctcat aaagtttgtt tgtatcttct aaatcatata gattaacaac
    29041 acattctggt acatcttttt ttatattctc aactgtttgc tctgctcttt tataaaaatc
    29101 atccttagga ttaaagatag atatttctct tgctccatct aaagcacatt gtacttgtat
    29161 agcagttgct gcaccaccag cacccataat tgtaatcttt ttacctttaa cttctacccc
    29221 attttctttt aaattacgaa catagcctac tccatctgtt atatgaccaa ctaactttcc
    29281 attgtcattt acaattgtat tacatgctcc aattatacga gctgctggag aaagttcatc
    29341 catatattct gtaacagcag atttacatgg catagtaaca ttggctcctt ttatattaaa
    29401 agtttttatt gctaaaagtg cctcttttac cttatctact gtgatatcaa aggctaaata
    29461 tctataatct aaatctaatt tcttaaaact ataattatac atcactggtg atttagagtg
    29521 accaaccggt gtacctatta atgcaaataa tcctgttcta cctgaaattt ccataactat
    29581 aatctcctct caatattatc attttctttg caaataacct attcagttat ttacaaagaa
    29641 aaatttattt attatttata tatttaatgc tacttcaaaa gcttcttttg ttgcatctaa
    29701 tgccctacga gcttttactg catcaccaac aatataagtt tcttttacaa cttcttttat
    29761 aacttcactt aatgggtcgt aattacgaga acccatagca agtactactg aatcaaaacc
    29821 ttttaaatca tgctctgtgc catctgtaag taaatagtcg acaccatcat cataaaattt
    29881 agaaactttt gcaccagtaa tggtatgtat attataattt tcaaaatcat tcataaggaa
    29941 tttacggtgt tctgaaatta catctgcacc aacttcttct ctaagctcaa taacagtaac
    30001 ctcatgttct tgttctccaa ggaaggctgc cacttcacat ccaaccattc cacctccaac
    30061 aacaagtact tttttcccac aagatttttt accatcaaga aggtctacag catgaattaa
    30121 tcctgaatca ttgattcctg gtataggaag tacaagtgga gttgctccag tagctataat
    30181 aactacatca ggtgatttct cctttataag ttctactgta gcttctgtat tagtacatat
    30241 ttttacacca tattgattac attttgaaat ataacttcta actaagttag taatatctcc
    30301 tttccctgga ggatatgcag ctaaacgcat ttgcccacca agaacttcag atttttcaac
    30361 taaagttaca ttatgtcctc ttttagcaca tacccatgct gcaagcatac ctccaacacc
    30421 tccaccaaca acaagaactt ctttgctaat ttcagctggc ttaagctctg cttcatgtcc
    30481 taatatagga tttgcaagac aggctatagg tttgccttgg aacatatttg gtacacatcc
    30541 ttgtaagcat gcaatacatg gtatcatttc gtctagtttt ccatttttag ctttattagg
    30601 catttctggg tcagccaagc tttgtctacc gaatgctact aaatcacatc ttccttgtct
    30661 gaccattaac tcagcaaact gtggctctgt ataacgtcca actgttatta ctggtatact
    30721 aacagctttt tttatttcag taactaattc tgcactgaat ccagcatgta aagtcgtagg
    30781 agcccacata tattcatcat gtatatgtat actacgtgaa acatgaagtc catctattcc
    30841 acaatcttct agatatgctg ctattactga actatcgtgt acatcaattc ctcctggaac
    30901 atcatcagtg ctgtttatac gacataatat tgctagagaa tttcctactt ttttacgtat
    30961 attttcaatg ataagacgag gtaatctcat tctattttca aaacatccac caaactcatc
    31021 tacacgctta tttgttcttt gtgatataaa actactaacc agatatccat gagcgcagtg
    31081 aacttcaaca gcatctgcac cagctttttg tgcacgtaat gcagcatctc cataagattc
    31141 tataagttca tatatttctt ctgttgttat tgctagtggt gtattacgac catttgatgc
    31201 aggtattgca gaagcagctt ttaatggatg tcctgctact ttttcatttc cttcagaacc
    31261 agcatgttgt aattgtatag ataccttcga acctgcatca tgacaagcat ctattacatt
    31321 tttaaaacta tctattgtgc tatcatcata taaacaaggc ttacgaggac ctccttttgc
    31381 ttttttgtct acaacactag attctatagt tattaatcca aaaccaccta aagcacgctc
    31441 aagataataa gccttagaag tttcacttaa agtaccatct gtgtttgcaa aattgtttcc
    31501 cataggggga actacaaaac gatttggaac tgtcattgaa ccaattctta taggtgtaaa
    31561 catagaacta atcttcataa ggttttcctt cctttcaagt tttatattat aatactctgt
    31621 atatttttat attatataag tttattttgg agatacttca gaccatgctt tatccaaaac
    31681 ttttttagtt gcattaaata cagtttcagc agcagtggat aaccctttag atattagaga
    31741 atcagatatt acttctgccc ctatgactct tggtgatata ttgtgttctt ttattatttt
    31801 cacaaattcc tctgtgtttc catatccttc acctggagcc aaacggtcat gtagtgattc
    31861 atccctaagt ttttcataag gagtttctaa aacatcacac acttgaattg atactatctt
    31921 atctgctgga acaggtgcaa ggtcctctgc tgtctgcttt gctctagccc agtgccaagt
    31981 atctaatata agcattgcat tttcacgatt acatcctttc acaacacgcc atgcagtagc
    32041 caaatctggt acaccactat atggcataaa ctcaagacct ataataagtt cacctgctct
    32101 gtcacataat tctcccaatg cagttataat ttgttcttct ggtatcatct ctaataatcc
    32161 acaatttata tgtttaacat taaataagtg agccatatga taaacatttt gctctttttc
    32221 tctttgagct tccgttctat cttcttctct tccccattga gttatatatt ctacttctgt
    32281 aactttcata tcatattcat taagaattgc aatcatttct tcatctgtaa cacctgcatt
    32341 ttttgcatca atataatttt cagcacgcaa tccaatacca tcaaacccag cttcttttgc
    32401 aatacgaact ctatcacgga atgaaacttc tgttcccaat gtataagaac taattgtaat
    32461 tggaatatta agattttttt gattattcat agcttaaatt tgcccccttt attttcttta
    32521 taattaatag tatttttgat tttatatttt tatttatcct actagtagta ttattttacc
    32581 ttaaaaataa aagtattttt tgatttctat ttatctagat tttataaatt tattgtatca
    32641 cgagacttta ctaataacaa attgataatt tcctattaat tcatagattt tgtttataga
    32701 ttttatttat aagataattc ttgtattttt ctattaggtc gtataaatat atttatctta
    32761 taattcagac aaaaaacgat aaattttttt aaaagctttt attcttactc tataatcata
    32821 tataataaaa atgtaaaaat atcttaaagg ttaacttcta caaatatata aataaaaata
    32881 cctatgaaag gatgaacaaa aattgaattt atatcactta cgctattttg ttacattggc
    32941 acatttagaa cactatacaa aagcggcaga aaatttatct ataacacaac caagcttaag
    33001 tcatgctatt tctttactag aaaatgaact tggggtggct ctatttgaaa aagaaggtag
    33061 aaatatagtc cttactaagt atggaaaaat atttttaaaa gatgtggaaa aatcattaga
    33121 aattttagat tcaagtgtaa aatcattaaa aataactggt actggtgaag gacaaataga
    33181 cttagctttt cttagaacac ttggtactga ttttatccca gacatagtgc acaaattttt
    33241 aaaatctaat cctgctaaat caatagattt taaatttcat actggtgtaa ctactgacat
    33301 tattcaaggt cttaaagaaa gaaaatatga tattgcattt tgttcgaaac ttgaaaaaga
    33361 aaagggaatt gaatttatac ctgttgccaa acaagattta gtactaattg taccatatag
    33421 tcatccacta gctgcaaagg atactataga tttaaaagaa accatacctt atcctcaaat
    33481 agtatttaat cagagaagtg gtcttagata tataattgat gatatgttta aaaaaataaa
    33541 tcaacagcct aatatagtct atgaagtaga ggaagaccaa gtaattgctg gattagttgc
    33601 aaaaaatttc ggaattgctg tagtcccaaa tatgaatatg cttagcttta caaaagtaaa
    33661 agtaattcag attattcacc caagttggga aagaaacttt tacttagcat ttataaaaga
    33721 tagatatttg cctcctgcaa ttaaaaactt taaaaacttt gtcattaaaa acgctcaatt
    33781 ataatttatt aataaagggg ttatttttaa atatcctctt ttattctttt tataaaataa
    33841 aaaaatctat acttttaaaa gtatagattc ctaactgaca gtcggcatcc gagtctcagt
    33901 aattatcgtt atacaacagc aactggattc agttcctgaa taactaggtt acttacatta
    33961 tatcagattt tttaaaattt gtcaattgta tctaacgcat tttttcaagc catggtccaa
    34021 caggctctac aataggaact tctttaaatc cccaatttct tatatcattc acactcgttg
    34081 gagtatatat tttgtttctg acagatttga atattttgtt tttttctcca tattgcatac
    34141 actttggatt agcttctatt aaccctcttc ttgctctgct aagaggatta cataaaatat
    34201 ctgctatttc taaaccttct ctatagtcag catcttcttt tttggcaatt ataaaaccct
    34261 taaccttatc tcttaattct tcatctatat ctaagtatat tgttccatta ttaaatacat
    34321 caaaaaacgc cttttgtact tttaagtttg agacatcatc ccttgactct ataactattc
    34381 gtgcagattc tacagtttca ttatttacaa atgaataaaa attctgaaga acatgtataa
    34441 aagccacaac atacggttcc tttgaaggtg cataatattt ctttaatcta gctttatcta
    34501 ctgttactga tattatagta cactctaatc tagatagaaa taaaggcaac tcatcataga
    34561 ataacttaat ctgtgaatca tcaaacttct caaatgctct tgattttctt gatatatctg
    34621 tcaaatgtat tcctatgtta ctggttccaa aacaatactc tttaaatgca tccatttctt
    34681 tcctcaaaga acatacataa tcgccttgac ttactgcata tttatattca aaaattactc
    34741 ctgtcaatgt aaatgggtct tcatgattta tatcagctct tccactttca tcaataaaca
    34801 ttatatattt tttctttata atcttactca ccctcttaac atatgatgat agcatctata
    34861 ttcattttat atgagtttta aaaatattcc aagattttta tataacttaa acttaatttt
    34921 atactaaaaa attgagatgt aaaacaatca agcttttatt gattgaattt cacatctcaa
    34981 ttataattat ttttcaatat atatttttac tattttgcaa gaatatccat taatttatcc
    35041 attactatat aagatactcc gcctcctatt tgataaggag tttcaacttt tttatttgca
    35101 aatactcttt gttgctctga tgataatcct gaattatcca ttaaaactat tggtgaatgt
    35161 aattttacag ctaatggtcc agctgataaa gcatctacta aagcatctga tttactaact
    35221 aatacagcct gtaaatcagt atctccatag aatttttcta tcactttggc attagtatct
    35281 actctactat ctccatatat tctatttcct gaaatatctt cagtagttat atcattcatt
    35341 tttgctatta ctgaatcgtt aattgcactt ggtccaccta taaagtatgc attttctaat
    35401 tttctttctg ttagccattt ataagattct tctgtaattc catctttatt gactaatatt
    35461 ataggttgtt tttcttcccc agctttagaa gctacagata aagcatctgc ctccccattt
    35521 ccagaaacca tatatgcagt ttttatttct tctcgatttc caagttcttc agctattctt
    35581 gtagcagttt gatatctatc ttgacctgct attctctttg tttctgtgtt gaaagtagtt
    35641 tttatttctt gctctaattt agaacttatt acattttctc cacctatcaa gattactgtt
    35701 ttaggtgcta ataacttcat ttcttcaaca gtttcagttg gtaaattagc tgtattagta
    35761 agtagtattg ttgagtcata gctacttgct aaaggagttg ctgttatacc atcagctatt
    35821 gcattaccat ttactaatat tacagtatct gaactatcag cattccagtt tccaactgaa
    35881 cttatctttt tagctgtatc aaatctattt gcacctataa ttgtatccca tgtaggattt
    35941 atagttccat cttcattaaa agtataatct ttcccatcta ttttttgaga accagttagc
    36001 atctttccat ctttgtctaa atagtaagac ttaccatcta tttgttgcca tcctgtctgc
    36061 attattcctg ttttgtcaaa gtaatactta ttaccatcta tttcttgcca tcctgttact
    36121 gctaaaccat cagatcctag atagtatttc tttccattct tttcttgcca tcctgtttgc
    36181 attactccat ctgagttaaa gtaataagtt tttccgtcta ttactttcca tccagatact
    36241 cttgctccat cagttcctaa ataatatttt ttgttattaa ttgttttcca tcctgtttgc
    36301 attactcctg aagcatcaaa gtaatacatt tttccattta cttttagcca actattcttt
    36361 tggtatgttc catcagattt tacataatac ttcttaccat tttctgtttt ccatcctgtt
    36421 tgatttagat ttatcttata ttttgccgct atctttacat agctgtcgtt actataatct
    36481 ataattacat ctgaacctac aggaacttgg tcaaataacc atctaacatc tttattgtgc
    36541 attcttatac atccaccaga aatatgcttt cctatagaac tctcattatt atttccatgt
    36601 attccatatg tatctccata agttcctttt aatgctaatc ccatccatct atctcctaat
    36661 ggatttcttg gacttcctcc aggtatatta cctttataat atggtctatt ttttatcttg
    36721 ttaactactt ttgttttccc tgttggtgtt tctgacccct ttttacctgt tgcaactcta
    36781 aattctttta caagtttatt atttacaaaa tatcctagag tattttttct tgaatttact
    36841 ataatcacat gtttactggc tgcgcttgat tctggtacgc cacatgcaaa tactaaaact
    36901 aaagtcagtg ctagtactaa atactttttt agactttttt tcactataac ttccccctct
    36961 tttagaaaca ttactacatg tgtctaatta taacataaaa ttaccaatac cttatattta
    37021 caaatttgtt acatttatac atataagtat gtattctact cttcataccc attaggattc
    37081 atactttgcc atctccatga atcttcacac atctcttcaa gttcatactt agctttccat
    37141 ccaagctctt tttctgcctt tgaagaatct gcataacaca tggctacatc tccagccctt
    37201 cttcctacaa tcttatatgg tatttctttt ccacttgctt tagaaaatgc ttttactaaa
    37261 tcaagaacac tatacccctt tccagttcct aaattataaa caacaagtcc tggattttct
    37321 tctaattttt gtaatgcttt tacatgacca gcagctaaat ctaatacatg tatatagtct
    37381 ctaactccag ttccatcatg tgttggatag tcattaccat aaacactcaa ttccttcaat
    37441 ttacctactg ctatttttgt tatataaggc attagattgc tcggaactcc atttggttct
    37501 tcacctattc taccactttt atgagcaccg actggattaa agtatcttaa aagagctata
    37561 tccaatgact tatctgcttt tgatatatct actaacatct gctctatcat aagtttagtt
    37621 cttccatatg gattggttac agaaagtgga aaatcctcta atataggaca agtatgtggg
    37681 tctccatata cagtagctga agaactaaat acaaactttt taacaccata ttctctcatt
    37741 aattcaaata aatttaaggt acttattaga ttattgctgt aatattcaat tggtttttct
    37801 actgattcac caactgcttt taaagctgca aagtgtataa ttgattcaat attattttct
    37861 ttaaatacaa catgcatttc atctttattt ctgatatcaa tattataaaa ttttactggt
    37921 tttttagata attccttgat tctatcaacc actattgagt tgctattact taagttatca
    37981 actataacaa cttcataacc tgattctaaa agttctattg ctgtatggct tcctatatat
    38041 cctgctcctc cagctactaa aactgccatt gtaattacct cttttctaat atttattttt
    38101 cacttacttt ttttctcata tagtccatta aatcatcttt taaattttct ctctttagag
    38161 caaagtctat tgttgcctct aaaaaaccaa ttttatctcc cacatcatat cttctacctt
    38221 caaagttata agcataaata gcctcttgtt ttccaagagt ttgaagtgca tctgtcagtt
    38281 gtatctctcc acctttacca ggtgtctgtt tctctaatat gctaaatatt gcaggagtta
    38341 ttatatatct tccaagtata gctatatcag atggagcttc ttcaattgca ggtttttcaa
    38401 ccatatcttt aactttatat actctatctt cgatatgttt tacatccaat ataccatatt
    38461 tattagtatc ttctttagct atcttttgaa cacctaatac agttgtttta tactcattat
    38521 aagtatctat taattgtttt aagcacggaa catctgaatc tactatatca tcacctaata
    38581 atacggcaaa aggttcatca cctataaaac tttttgcaca gtaaattgca tgtccaagac
    38641 cttttggctc tttttgtctt atataatgaa tatttaccat atttgatatg tctcttacca
    38701 tttctaacat ctctgtctta cctttttgct ctagttctaa ctctaattca actgatttat
    38761 caaaatgatc ttctatagat tttttatttc tacctgttat tataagaatt tcttcaattc
    38821 ccgattctat agcttcttct attatatact gtaaagttgg tttatctact ataggaagca
    38881 tttctttggg ctgtgatttt gttgctggta aaaatctagt tcctagccct gctgctggta
    38941 ttattgcttt tttaactgtc atctgcattt tttcaccctt cttcgtaaat tttctattgt
    39001 accaaattaa tataccatat ttatactttt tcttcaaact ctatattatc ccaatattta
    39061 atgctataag ataatataag gtagatgaaa tttcatctac ctttagtttt ataagttaat
    39121 attgtattgt ttatatttta tccaaaactt atacaggtac taaatttcat ctaagatgcc
    39181 ttttatatca ctatctatat cttcatctag ataagaatct aaatcttcta agtcaacttc
    39241 tagttcttga tatgtcatat caacactgac atcctcatct atatccattt ctgatattaa
    39301 ttctcctaaa atactatttc catcagaatc taaaccacta tctatatctt catctatata
    39361 gttttcattt aaaatttcat ctaaatcaat ctcgtaataa acttcattat ttttttcatc
    39421 ccctgagtcc aatcctaaga actcatagtt aaaagtccaa acattgtatt tacttgacat
    39481 actttattcc tcctgtgaaa aacatatttt catctagttt attggttcca taatcaacag
    39541 agttatatat tttttcaatt atgtcttttc ttctttcttt tgtactatta tttaatgtca
    39601 attgtttaaa tacatatgta tttgttattc tctcgaataa tatttctttt atactatcat
    39661 catcaatatt tctatagttt ttccacaata actcaaataa cttaaacatt tccctactag
    39721 tttcatctac ataataagga tacatatttt ctactaaatg gtttaatctt gatatggctt
    39781 gttttaaaaa tacatcaaga cttgcacttt cactttcttt taacattcta taattgtatt
    39841 tcttcttatc ttctcctgaa attacaaaga tgatattgtc taaacttttt tcaacttcat
    39901 ttaaataact gcttatatta tatgataaat cagacaatag atttttaatc tgcttaaaca
    39961 cttgtacatc aagtttagta ttatactttt caaacaaatc tatttcttga ttttctaata
    40021 ttcttggcat atatgctgac aataaatcta aattgtttct ttgttcttgt atttgcttat
    40081 aaagtgaatt tataacttct attcttattt catcatttaa ctctttttct aaaatcttat
    40141 caaattcaga tttcatatag taaatatttc caaagaaatt aaatattatc atatcattca
    40201 tagctttaga ccaattctta tatatcactt caatagaatt ttctttaagt agaggttgct
    40261 ttgcatatat aaatacatct tgcataagtt tttgaaccat acttttactt aagtttaaaa
    40321 gtactttttg attattaaat tttatttccg tttctacaaa attagaattt tcgttttcaa
    40381 gttctttatt aattacaatg tcttttatat cactattttt tatagatatg atttcttttt
    40441 gaaaagactt tagaatagtc aagctatcga aatcttcttg aataaaaaat ggagcatgtt
    40501 ttaatgtata tcccactatt tcattttcta tatcttttag gtcatctatt tgcataattt
    40561 ctctattttt atcatttata tgtaggttaa atacattttt attatcatat aatattatat
    40621 cttctcctaa atttaactta gaacaattat ctttcgctga ctttacaata gtcttcttag
    40681 atttcttatt tataaaaatt aattggtctt gatattttac taaaagcatg tttgtgtttt
    40741 tataatcaaa tccatctata tttcctgata tcttgcagaa tactatttca caatctttag
    40801 gaagatttcc tattttttgg ttatctttaa ctctctcatt taaatcagat gggactacac
    40861 tatctatatt gttattaaat atagatacag accttactat aatcccctct ctttccatat
    40921 gaaagtatcc cttcaatgac actcttttat cttctaaaat gtatctttct atatcatcaa
    40981 aatttatttc aaatctattt ttcccactga taaatataaa cttctcatta tctttattaa
    41041 ttccacccat ataaaactta ttgtcatcta aacttaatat agtcatatta tcctttagat
    41101 agaatataaa ttctctttga cttttgcaga ttaaatcata ttcatccaaa gttattttca
    41161 tagtcaaatt tgctgtaaca tttttacttg aattttcact ttttatgtaa aaaggcaagt
    41221 tatttccata gacaattatt tgagaatctt ctaaaactgc ctctaatttt tctttattgt
    41281 ctgaaaaact atatatatat tttacacctg tatcctcatt aacttcatct gatttgctga
    41341 ttattatatt ccctagattt gttatatgaa gctttttata ttcttttgag tatctactta
    41401 tgccactaag ctcaaaccca tctgaaagct catatatgat tttttctcct aatttcaaca
    41461 taccttcacc acctaaacag aattataagt attttataaa ggtgaataaa atgtctcaaa
    41521 acaaataata ttttttttaa tactttttat tctgagacat agtttctcct tttttataat
    41581 gctctaagca ccttcaacta tttcttcata aagtttatct aaatgtttaa catattcacg
    41641 atatccagat ttgttcttta actcacttct taaatcttca tatttttgtt taagttcttc
    41701 agcactcaaa gaaggagctg attcttttaa ttcttctaac ttataatcat agtacttatc
    41761 atacatagct atatatgtat caatagactt cttagctagt tcattacatt tttcttgtgc
    41821 ttctccatat tgagaataat cacctatttt tattttatag tatccatttt cttgaattat
    41881 tgttgaagaa atacctttag cttcatattc ttttgctgtt tcttttgctg ttttttcaac
    41941 tttaagtgaa cctgcataaa cagtgtaata tacaccttta ccatctttat atgcttccat
    42001 ttcttttgct ttcttttcag cttgtgcttt ttcttgagcc tctttttcag cttttgcctt
    42061 ttcttctgct tcttttttct ctttttcagc ttgtgctttt ttctcttctt cagttaattt
    42121 attgttagct tgttgttgag ttgatgactt tggaatattc tctttatcat ttttcttatt
    42181 gttgcctact gttataaaat atcctacacc aacaataacc actataacta ctgctataat
    42241 agtttctttt aatctactct tcttagaaac aacctcttca tcatctaaag aatcttcttt
    42301 atctgataca taatttttca tttctttctt gttttctcta tatttgtcct tagaagaatt
    42361 tttagatttt ttattactat tttctttctt tttaataggt attactactg atttttcatt
    42421 ttctaatttt tcttctttta tttcttttgc ttttttatct tctaagtttt tactttcttt
    42481 ttcaagcttc gattcattat ttgaagatac tttttcatct aagttattat ttattggttt
    42541 ttctattttt acactacgtt cttcttctat atgttgactt ggttcttctt gttttatttc
    42601 tttcaattca ttttgctcta tttcttctga tttcacttga tgattttcaa ctggtttatc
    42661 taaaattata tctggagaaa tatcatttaa attctcttct tcttgttcag cttcttcatt
    42721 gtctttttta ataaatccaa ataatttagc cttcttttta ctctttttat tttctggttc
    42781 aattatatct tctttattgc tgtcgtactc tttatctgta gtatctttat cttctacaac
    42841 gtcacctata tcttgattat tactatctac ttcttcttta gtcccttctt cagcatcatc
    42901 ttctattgaa atactacttc taaagcaaat atctttatct gcatttttta tcatgtaaat
    42961 gtattcttca atatcgatat ctttatttct tctagttctt tttgatgcaa tttcatgatt
    43021 ttctaattca ctatagttat cttttattag attctgtgct ttattccatg tatcttcact
    43081 aatttctgtt ttatttttaa ttacatagtc cacaaattcc ttaaaatttt caggaccaaa
    43141 ttctccaatt atagtcagtc tcattgcacc ttctataagg tctctatttc ttctctttaa
    43201 aaattctaat acaactgttg cacaagcaaa atctttaata atttctttgc caaaaccata
    43261 tgcttcaaca gaatgaagtt cttctaatcc acataacttc ttatattcat tgtgtattgt
    43321 ttgagatata ctttcattat ttaagctatt taacttatct ataaacttcg attctatatc
    43381 atttgatttt gattcatgtt ttacttttga atttttaatt tcatttagta gcatgtcatt
    43441 ttctgaatta tctttaccta attgcaaatc ctcaatttca gttgctttta tttctacttt
    43501 gttttgttcg ttattctctt ccacattatt aggtaccaca tctttattac tagctaatat
    43561 tttgtttaca cagaatataa tttctctttt taattctctt ttcgcatctg cttgattttt
    43621 aagaaataaa tctccacatt ctttcttttc taaacttatt tttctaagag atatattaag
    43681 aaggtcttta tataggttta aaaccttata atccttttct aaacgtcttc ttctctctga
    43741 tagttccatt ttatcataag ctaaaaaact atttaaatca ttggctttta gagagtctaa
    43801 tccctctttc atagccttat ttacatactt tctacatttt gctgtagtta actctaaatc
    43861 tttttctaat tcatctattt caggtatgta cttatctact atccatttgc caataagtgg
    43921 ttctgtattt cttgctaatg tcttataaaa caatatatta aattttaaaa gctctgcata
    43981 ttttgcttca ttaaattcta ctttttcaaa tttcttttcc aaaacaccat ctagcttttc
    44041 atttatttta gactcttgtt ttaaaaaact tgctgtgaca tttaaaacag tgtttcttat
    44101 tatattattt tcactcaaaa ccttcactcc ttaaatcaat tattttattg taatatttac
    44161 attgtgcaaa gttgctaatt tgattatgat atctaaataa ttatttacta aatttgctac
    44221 atcttatatc atatcatatt atttacatca ttttactttt tctttttata tctatcttat
    44281 attataccat ttttaatatc tgtactaact tatattacaa tattcctcaa aattttaaaa
    44341 gtagattaga caaatttaca aataaaaaaa catcagttta aactgatgtt tttgactatc
    44401 gaaataatta agcaagtcta taagcggagt tctgtattag ataatcatct ttctaggcct
    44461 attgtcacca ataggctcaa gcgacctacc taccggagag tacgagcagc actctttatt
    44521 cctatcttgg tcttgctcca ggtggggttt acatagccaa ctagtcgcct agctgctggt
    44581 gagctcttac ctcgcctttc catccttacc acaatagtgg cggtttattt ctgttgcact
    44641 atccttagga tcgctcccac taggcgttac ctagcaccct gctctatgga gctccgactt
    44701 tcctcatgta agattacatg cgattatctg gcttacttaa tatttatttt acttagttat
    44761 gttaacacaa attcttttac atgtcaaagt aatattatac taaaaattta aatttattca
    44821 aaaatagtgt aatatagata tataaactac atttaactcg aggtgatcta ttgaaaaaat
    44881 tatatagaat agtaattaac attatactag tattagtaat actttacagt ggatttaata
    44941 tatactcaaa acttaccaaa tacaatcatg atactaaaat atcctcagaa cttcaaaaaa
    45001 aagaatataa aaaagaggat ttatcaaaga ttaacagtga ttttaaattt tggctttctg
    45061 ttgagaatac aaatataaat tatccagttg tacaatctaa agataattct tactatcttg
    45121 acaaagattt ttataaaaaa gattctattt ctggtacact gtttatggat tatagaaata
    45181 aatctattga tgacaaaaat atcataatat atggacataa tatgaaaaat aaaactatgt
    45241 tcaacaacct aaataagttt aaagatgctg acttctttaa aaaaaataat aaaataaaaa
    45301 taaccttgaa tggaaaagaa tttttatatg atgttttttc tgcttatatt gtagaatctg
    45361 attatgatta tctaaaaaca aattttaaca atgaatctga ttatcaaaat tacataaatg
    45421 atattacttc taaatcattg tataaatctc ctattaaggt aaatagcaat gataaaatag
    45481 ttacactttc tacatgtacc tatgaatttg atgatgccag aatggtgatt catggtagat
    45541 tgatttaaaa ctcacagaca cagtttaaaa caataatttt aaactgtgtc atcttttata
    45601 cctataattt gtaaattaga ccactaaaag tatttaatac aaaataacaa atacatcaaa
    45661 caataaaaaa caataaaaaa agactatgct aaaaacatag tctttactgg agctggtgat
    45721 aggaatcgaa cctacaacct gctgattaca agtcagctgc tctaccgttg agccacacca
    45781 gcacacctat tttattgtaa attagcaaaa ctaattttta aaagtta
//
LOCUS       DAYAKB010000027        44147 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.027, whole genome shotgun sequence.
ACCESSION   DAYAKB010000027 DAYAKB010000000
VERSION     DAYAKB010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.027"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            341..1048
                     /locus_tag="ACGI3L_001786"
     CDS             341..1048
                     /locus_tag="ACGI3L_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197496.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            1042..2352
                     /locus_tag="ACGI3L_001787"
     CDS             1042..2352
                     /locus_tag="ACGI3L_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9197497.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNVAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKSEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            2469..3152
                     /locus_tag="ACGI3L_001788"
     CDS             2469..3152
                     /locus_tag="ACGI3L_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197498.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDEPFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            3145..5532
                     /locus_tag="ACGI3L_001789"
     CDS             3145..5532
                     /locus_tag="ACGI3L_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9197499.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGKMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKLNDKSNLSI
                     EQAKSKLNKIANDVGLDTINVAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQVKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            5812..6954
                     /locus_tag="ACGI3L_001790"
     CDS             5812..6954
                     /locus_tag="ACGI3L_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HFG9197500.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            6973..7497
                     /locus_tag="ACGI3L_001791"
     CDS             6973..7497
                     /locus_tag="ACGI3L_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9197501.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            7597..8415
                     /locus_tag="ACGI3L_001792"
     CDS             7597..8415
                     /locus_tag="ACGI3L_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6597 domain-containing transcriptional
                     factor"
                     /protein_id="HFG9197502.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYIASNIHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            8493..8804
                     /locus_tag="ACGI3L_001793"
     CDS             8493..8804
                     /locus_tag="ACGI3L_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HFG9197503.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSVSSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(8981..9664)
                     /locus_tag="ACGI3L_001794"
     CDS             complement(8981..9664)
                     /locus_tag="ACGI3L_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197504.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(9757..10407)
                     /locus_tag="ACGI3L_001795"
     CDS             complement(9757..10407)
                     /locus_tag="ACGI3L_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9197505.1"
                     /translation="MSFLGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDG
                     LSRGAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHTYEQHN
                     KQDIFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMF
                     GFLLNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(10572..12575)
                     /locus_tag="ACGI3L_001796"
     CDS             complement(10572..12575)
                     /locus_tag="ACGI3L_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFG9197506.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELMKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(12728..13366)
                     /gene="recX"
                     /locus_tag="ACGI3L_001797"
     CDS             complement(12728..13366)
                     /gene="recX"
                     /locus_tag="ACGI3L_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFG9197507.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            13642..14331
                     /gene="nadD"
                     /locus_tag="ACGI3L_001798"
     CDS             13642..14331
                     /gene="nadD"
                     /locus_tag="ACGI3L_001798"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFG9197508.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            14332..14904
                     /gene="yqeK"
                     /locus_tag="ACGI3L_001799"
     CDS             14332..14904
                     /gene="yqeK"
                     /locus_tag="ACGI3L_001799"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFG9197509.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            15021..15371
                     /gene="rsfS"
                     /locus_tag="ACGI3L_001800"
     CDS             15021..15371
                     /gene="rsfS"
                     /locus_tag="ACGI3L_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFG9197510.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            15725..18145
                     /gene="leuS"
                     /locus_tag="ACGI3L_001801"
     CDS             15725..18145
                     /gene="leuS"
                     /locus_tag="ACGI3L_001801"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFG9197511.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDILDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            18998..19666
                     /locus_tag="ACGI3L_001802"
     CDS             18998..19666
                     /locus_tag="ACGI3L_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFG9197512.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            19706..19786
                     /locus_tag="ACGI3L_001803"
                     /pseudo
     CDS             19706..19786
                     /locus_tag="ACGI3L_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(20149..20421)
                     /locus_tag="ACGI3L_001804"
     CDS             complement(20149..20421)
                     /locus_tag="ACGI3L_001804"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9197513.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(20451..21266)
                     /locus_tag="ACGI3L_001805"
     CDS             complement(20451..21266)
                     /locus_tag="ACGI3L_001805"
                     /inference="COORDINATES: protein motif:HMM:NF026010.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HFG9197514.1"
                     /translation="MNIKSAFIRKRGEKFYVYVEYIEETTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFVAPKDMTFVERCYKYMDMNKNNWSPYTVTNTKSWVKNYIEPLF
                     KNLKLTEVNPSSVQAFVNYNFNNSTFTSAKVRYSFLSSVIREAYRLREIQENSCDFIK
                     LPSKEKYSTNEIYNRKEVLLLIEKLLSNNIEIPILLMLLLGLRMGEATGLRWSDVDLD
                     NNLINVNQILVYSNGKISFKEPKTPKSKRALSAPKELIEKLKIKKLRQSKLKL"
     gene            21482..22852
                     /locus_tag="ACGI3L_001806"
     CDS             21482..22852
                     /locus_tag="ACGI3L_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HFG9197515.1"
                     /translation="MKLKKLLSLGLVSMFVAGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLKDKGIETRRLQGNDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            23146..23304
                     /locus_tag="ACGI3L_001807"
     CDS             23146..23304
                     /locus_tag="ACGI3L_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197516.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   23590..24148
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=23590..23619
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaatt"
     regulatory      complement(24289..24386)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            24688..24996
                     /locus_tag="ACGI3L_001808"
     CDS             24688..24996
                     /locus_tag="ACGI3L_001808"
                     /inference="COORDINATES: protein motif:HMM:NF015898.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9197517.1"
                     /translation="MSKDVADEIEKTYAWKHTTTITLLARLTKKGFFISQRIGKHVHY
                     RVLIKEKEYLKIEGKRIFGGLHNNPLSELISKLHDGEEITEEKIIEIGNWIKSWKDED
                     "
     gene            complement(25174..26169)
                     /locus_tag="ACGI3L_001809"
     CDS             complement(25174..26169)
                     /locus_tag="ACGI3L_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFG9197518.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(26290..27918)
                     /gene="aspD"
                     /locus_tag="ACGI3L_001810"
     CDS             complement(26290..27918)
                     /gene="aspD"
                     /locus_tag="ACGI3L_001810"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047688 - aspartate 4-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006531 - aspartate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HFG9197519.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            28577..29794
                     /gene="ilvA"
                     /locus_tag="ACGI3L_001811"
     CDS             28577..29794
                     /gene="ilvA"
                     /locus_tag="ACGI3L_001811"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HFG9197520.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            29889..30269
                     /locus_tag="ACGI3L_001812"
     CDS             29889..30269
                     /locus_tag="ACGI3L_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFG9197521.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            30553..31035
                     /locus_tag="ACGI3L_001813"
     CDS             30553..31035
                     /locus_tag="ACGI3L_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9197522.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            31056..31871
                     /locus_tag="ACGI3L_001814"
     CDS             31056..31871
                     /locus_tag="ACGI3L_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9197523.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            31922..33472
                     /locus_tag="ACGI3L_001815"
     CDS             31922..33472
                     /locus_tag="ACGI3L_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9197524.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPFLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            33569..34921
                     /locus_tag="ACGI3L_001816"
     CDS             33569..34921
                     /locus_tag="ACGI3L_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFG9197525.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            35052..35810
                     /locus_tag="ACGI3L_001817"
     CDS             35052..35810
                     /locus_tag="ACGI3L_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197526.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            35857..36576
                     /locus_tag="ACGI3L_001818"
     CDS             35857..36576
                     /locus_tag="ACGI3L_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HFG9197527.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(36700..38100)
                     /locus_tag="ACGI3L_001819"
     CDS             complement(36700..38100)
                     /locus_tag="ACGI3L_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFG9197528.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(38104..38994)
                     /locus_tag="ACGI3L_001820"
     CDS             complement(38104..38994)
                     /locus_tag="ACGI3L_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9197529.1"
                     /translation="MTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKATFYKHF
                     ETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRTTINTYI
                     RENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDALIHQFI
                     YIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYFSLHNKS
                     LFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAYLEKEDT
                     LRPKVLLLNSIKNQLKKETL"
     gene            39273..39920
                     /locus_tag="ACGI3L_001821"
     CDS             39273..39920
                     /locus_tag="ACGI3L_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9197530.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            40245..42884
                     /locus_tag="ACGI3L_001822"
     CDS             40245..42884
                     /locus_tag="ACGI3L_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFG9197531.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHIEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMNTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(42942..44045)
                     /locus_tag="ACGI3L_001823"
     CDS             complement(42942..44045)
                     /locus_tag="ACGI3L_001823"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9197532.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVREAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
BASE COUNT        16658 a         5326 c         7271 g        14892 t
ORIGIN      
        1 aatcaaaaag agttaaagga taaaaagtca aaataaaaat taatgagcaa aaattagtag
       61 atagtaattt aattttagat aatagtaaac agcaaaggaa attagttata taaatactaa
      121 tttcctttgt tttatgtttt aacatgatta cttttaaata aaattgtatt ttatgaaaaa
      181 taattatact aaatggcata gtattatggg gatttttagt ttttattcaa gtaaatgaaa
      241 tcatattaac aacttctgat atatttacaa attgataaaa aaatgatttt attagtatga
      301 tataatttag ctagtatgta tgataatgga ggatataggg atgaataata tattactttt
      361 ggaagatgac aaatctttaa atagaggaat tagttttaaa ttaaaaaaag aaggatacaa
      421 tgtttttagt gcatttggta tagaagaagc aaaaaatatt ttcgcaaaag aagagatatg
      481 cttaattatt tccgatatag gtctacctga tggtagtggt tttgactttt gtgaggagat
      541 tagaaagaaa agtgatgttt acataataat gttgacagct cttgatgaag aggtggatat
      601 tgtcacagga tatgatttag gtgcagatga ttatatcaca aagcctttta gcttgatggt
      661 attaatatca aaagtgaatg cgcttatgaa aagagtaaat acagtaaaaa attatactct
      721 attagtttgt gatgatttat tcttttatta tatagaaaat aaattaatta taagaacaga
      781 tgataaggaa gaagagataa ttttaagtaa gacagagaca aaactattaa aatatttgat
      841 ggaaaattct atgcagacat tgactaaaga gcaactgtta gaatctttat gggatagtag
      901 tggtaatttt gtagatgata atacgattgc agtaaatata agaagactta gacaaaaggt
      961 tgaaaaaaat ccatctgaac ctaaatatat aaaaacagta agaggggttg gatatatgtg
     1021 gggagaaagg agtataaaaa aatgctaaaa aatatgaacc tcaaagatgg tttaagtgtg
     1081 aaagatgatt atataatgag aagagttatt gtatattctg ttttatctgt actaatagta
     1141 acccttgtat ttatactttt tgaatatagc agattacata aattgtatga acatcaaata
     1201 aaaaatactc aaaatgttgc tggaatattg attgaaaaat atcctaatga tgaaatagat
     1261 atagtaaatt ctatttataa ttctgattat agtaaggtgt ctactggaga aaaggcattt
     1321 aagaaatttg gctatggatt ggaaaataaa atgtcaaatg ataaaaattt tagcttatac
     1381 ttaaaatctt tttttaagga atcatttttt atttttttaa tgatgtttat agtagttata
     1441 ggtataatat attattttat aagatacata aataaaagat tgagtaaaat ttattttata
     1501 gtagataaga tgtcacaaga aaactacttg aaggacacta ctgagtcaga agaaactggt
     1561 tatctagtag aatataatga atactttaaa gaaggcatat ttagtaagat aaataactgt
     1621 ctatatgagc ttaatagaag tttaaagata aagtttatta aattagaaaa agaaaaagaa
     1681 agtgtaaaat cattagtaac agatatttcc catcaattaa aaactccttt agcatcctta
     1741 aaattataca atacattact tatagaagaa gaattagaag aagatgaagc caacgagttc
     1801 ttattaacca ataaggcttc tataaataaa ttagaaaatt taataaattc tttagtgaac
     1861 atatcaaggt tagaaattag catgataaac ataaaaaaag aagataatga tataaaaaat
     1921 actattctaa atgcagtaaa aagtgttacc cctaaggcta agagcaaaag tataacatta
     1981 aatttaaatg aatttaacag tagaattata ccacatgata aaaagtggac tgaggagagt
     2041 atttttaatg tattagacaa tgctgtaaag tatacacagg taaatggaga aataaatata
     2101 tctgtagaag aaactgctaa tttctttaaa attataatag aggataatgg catagggatt
     2161 gaaaaaagtg agtttaataa tatatttaaa cgtttttata gaggttctgc tgatgaaatt
     2221 gaatctgtag aaggtagtgg ggtaggattg tatttaagta gaaagatttt agaagaacaa
     2281 ggtggaaata ttatagtttc ttcaaaagta ggaataggga gcaagttttc tttgtttctt
     2341 acaactatgt aatattaaat gaaaggaaaa tgtaagcctc tacatttatt atataagtat
     2401 aaacagctcc agaaataaaa aattaataaa atatggagta atataactta gaatgagagg
     2461 ataattttat gaaaatacta tatactgaaa atttatcaaa gcattatgga aaaggagaaa
     2521 gcttagtaag agctttggac aatgttgact tagaaataaa tgaaggtgaa tttgttgcaa
     2581 taataggaaa atcaggttct ggaaaaagta cacttttgca tatgattgga ggtcttgata
     2641 tacctacatc tgggaaggtg tatatagata ataaaaatat atttacatta aaagaagaag
     2701 aacttgctgt atttagaaga agaaaaatag ggtttatatt tcaaagctat aatttaattc
     2761 catctcttaa tgtatgggaa aatgtagtgt tgccaatcgg tttagatggt agagaggtag
     2821 atgaaccttt tataaaagag cttttaaaat cattaggact tgaaaataaa cacgacgttt
     2881 taccaaatac attatcaggt ggtcaacaac aaagggtggc aatagcaaga gcattagcta
     2941 caagaccagc tataatactt gctgatgaac caactggaaa cctagattct aaaacatctg
     3001 atgaggttat gagtatatta aaatctatgt ctaagaagta cagtcaaact ctagttatga
     3061 taactcatga tgacagtata gcccaaatgg ctgatagagt tatattcata gaagatggca
     3121 gggtgtcaaa ggttggtgat aaaaatgatt aatactacta aaatagcaaa aagtaattta
     3181 aagcaaaata aatcaaaaag tattctaata ataattacta taatactttc aaccttaatg
     3241 ctttcttcta ttggaattta tattgttgat gcaggagcat atcaaaaaga aaatactata
     3301 aagtattcag gtaattatca aggtatatta gcaaatgtag acgaaaaaca agctgatata
     3361 ttgagtaatc atgcagatgt tgaattaact ggtaaaatga atggagtagg tgttgaaaaa
     3421 ctggaagatg attcaaatat ttctctagca tacatgaatg aagatgcttt gaaattaaat
     3481 agttttgaat ttatcaaagg aaaattgcca tcaaaagaga atgaaattgt gttagatagt
     3541 ggagctttaa aggcacttgg ttataaaaat aaagatttag gtgaaaagat aaaaatatct
     3601 tataatgact ataaaagtga taaaaaaatt gaaaaagagt tcattataag tggaatctta
     3661 aaaactagcg aaatatctga agcaggtaaa tattattatg ctattatatc agaatcatat
     3721 atgagaaata ctagagatat gtcacaagaa gattttaata tatatgtgaa attaaatgat
     3781 aaaagtaatt tatcgataga acaagcaaaa tcaaaattaa ataagattgc taatgatgta
     3841 ggattggaca ctattaatgt agctgtaaat gaaaactata taaatgcttt aaaaccagat
     3901 atggaaacaa ttatgggtgg agtatttgta gggttagtaa ttgtattgtc tagtatttta
     3961 gtaatataca atatatttta tatttcaata gttacaaagg ttcaagaatt tggaaagctt
     4021 agagcaattg gtgcaactaa aaaacaagta aaaaatatag tatttaagga agggttcata
     4081 ttagccggaa tagcaatacc aataggaata attttaggct atgtacttgc aaatattata
     4141 ataaaatcat ttatggatat agatgtaaaa tcatcacgat taccagttat attatcggtt
     4201 gtggtaataa gctttatatc tgttgtttta tcacttttaa aaccaatgaa agtagcatca
     4261 aaagtatcca ttgttgacgc agtaagatat acaggaaata aaataagtaa taagagtaag
     4321 agaaaaggat ataaaaatat aaatctaaag agattatcac atgccaattt agaaagaaat
     4381 aaaaaacgta cttacatgac attggcatca cttatactta gtggaactat atttataaca
     4441 gtatcaactg ccttagaaag ttttgatgct gagaaaatgg caagagaaca ctttccttat
     4501 gatatagaag ttagactatc tggttatgaa atgaacagtg ataaaaatcc taaagataat
     4561 ttgaatattt tacaaatgga taatcctcta agtaaagatt tttttaatca aataaagaac
     4621 atggaaggaa ttaaaagaat agaatctgca agaagtgtaa aaattggtat ggaggactat
     4681 gatgttgaat ttaagtatga ccttttacaa agtataaatg aaaatgatgt aaaatcatta
     4741 aacaagaata taatagatgg aaaaataaat cttgaaagac ttcaaactgg agatgaaata
     4801 gtaattactc atgttgatac agcaaaagaa atgggagtaa aagcaggaga taaaataaga
     4861 ttaactttat atgatggaga taaaaagata aaaaaagaat ttaaagttca agcaatagct
     4921 atgggggttc caagttttgg tatagggaag gattttattg atagaacttt gaaatacgat
     4981 tcaactagta gcttgggaat atatacagaa gaaggaaagt atcaagaaat caaagatagt
     5041 atcaagaaga ttgctaaaaa taatggattt ttagagactg attttataga tagtagaatt
     5101 gagtcaaata aggctactat ttcatttata aagataatgg gatacacgct aacaggcata
     5161 ataggtgtga ttggatttat gaatcttgtc aacacaatga taactagcat agttactaga
     5221 aaaaaagaac ttggtatgct tcaagctatt ggtcttacta ataaacaatt agtgaaaatg
     5281 cttaattcag aggcaatgta ttacacttct ggaatgatga taggaagtat tctatttgga
     5341 ggtatattag ggtatattgc tgttatattt ctaaaaaaga ctggattatc ttatgcaaca
     5401 tattctttgc caatagtacc aatcttgttg atgattgtgt gtattcttat agctcaattt
     5461 ataacaactt atttgatagg acgaagtttt aataaagaat ctcttattga tagagtaaga
     5521 tacagtgaat aaaatacaaa tatttatggt tagtttaact agcaaaaaac atataaaaaa
     5581 atatagttaa agagattcat aattaaatag gttaaagcat agtacagagc aaacaattta
     5641 agcagatgtt tgctctgtat tttattatgt aatcaataat atatctaata tactgatatt
     5701 attcatgtta gaaaatgtac cggtacaatt ctaaaaaagt ataaaattgt accatataaa
     5761 atgaaaattt tgtataataa tcgtatagaa aataaatagg agctgatata tatgaataag
     5821 aagattaatt atgcaccagg accaactgaa actagggaaa atgtaagatt agcaagagca
     5881 gaaaaaacaa caaatccaga tatagatatt gattttgttg aattttataa aaagacatgc
     5941 gagaagtttg gtaatataat tggaacaaaa aacgatgttt acatattgag tggtgaagga
     6001 atattaggtc ttgaagcagc atgtgcatca cttacagaaa aaggagatag agtacttgta
     6061 attgacaatg gtatatatgg agaaggtttt aaagattttg taacaatgta tggtggggag
     6121 tatgtgcttt tttcaagtga atatactaaa agtatagata ttgatgaatt gaaagcattt
     6181 ttagatgagg atagtaattt taaatatgca acagtagtgc attgtgatac tccaactggc
     6241 gtattaaatg atgtaagcaa aatatgtcca ttacttaaag aatatggaat attaactgta
     6301 gttgattctg tagcaggtat ggtaggagaa agattaagtg tagatgaatc taaaatagat
     6361 ataatattag gtggttcaca aaaagctatt tctgcaccag caggacttac tatagtcgga
     6421 ataagtcaag atgcaaaaaa ttgtataaaa aatagaaaaa ctgatgtaat aggtttttat
     6481 tgtaatttaa atatatggga aggctattat gaaaaaaaat acttccctta tacaatgcca
     6541 ataagtgaca taatggggct tgataaagca cttgataata tattagaaga aggaatagaa
     6601 aatgtattaa atagacatga aaagatagct tatagtgtta gaaaatctat tgaggaatat
     6661 ggtctagaac tatttttaga agaaggatat tctaatacag tcacagctat aaaaattcct
     6721 gaaagtatag gagctttaga acttactgat tatatgctta aaaattataa tacacttgtt
     6781 gcaacatcac taaatcaata tatggatact attttaagaa taggtcatat gggagagaat
     6841 gcaaatctaa ataaaataga acatgtacta aatgttttgg ataaaagttt aagtgcatta
     6901 ggattcaaag gaaatggaaa tttgttaaat ttatttaata agtattattt ttaatagata
     6961 gggggatata gtatggaagt tacagctaag caaaaattta caacgaaaga catggtggaa
     7021 acctcactat taatagcatt agtatttatt gcaactaaat ttataaacat aagattacca
     7081 atatctataa atggtgggct tgtgcattta ggaactgcaa tgttgttcat atcagcaata
     7141 gtatttggaa gtaaaaaagg tgctttatca ggagctattg gtatgtcact ttttgatttg
     7201 atatctgggt ggactttatg ggcaccgttt acctttatag ttagaggagt tatgggttat
     7261 ttacttggaa agattgcatg ggcaaatggt aataatggga ataatttttt aatcaatgta
     7321 ataggaatat gtgtttcatc aatttggatg ctatttggat attatgtaac agaagttata
     7381 ctttatggta attttatagt acctcttact tcaataccag gtaatttaat gcaagtattg
     7441 ataggtctta taatagcgct tcctatttct aaggtattga aaaaatgtat aaaataaata
     7501 taaagtgaac taaaatttat gatagcataa attatactgt ataatattag gatggagtac
     7561 ataattaaaa aattttagta tagaggttag ttcacaatgt tatcagttac aagatattca
     7621 atcaaaaatg ttcgtttaaa gccgtgggta aagtttattt ggtattttga gacaaaatca
     7681 aatatactgt taaataataa gttacttccg acagacagta tagatattat tctcaatctt
     7741 tctgatgtta tggaatataa aattgaaaat caagactata ttgctagtaa tattcatttt
     7801 aatggaataa gggataaaca tggatttatt attcaacatg gaaatatacg tgttataggg
     7861 atttcttttt atccatttgg tctctatcca tttttaaaga taccaatttc agagtttaac
     7921 agacaaattg ttgacctaga agcagtatca aaactatttg caaaaaaatt agaagagtca
     7981 ttaaatccaa caaaagcaat agaaaaagtt gttttatgtt tagaagaagt attattatcc
     8041 atattagaag aagatttaat ttcaaataaa tatgtaaagc ttctaaattc atttatatat
     8101 gttaatagat atagcaatat aaaagcattt tgtgatgata caaatataaa tattaaaaca
     8161 ttggaaagaa tctgtttaaa atatacaggg tatacaccta agattttaaa gagaatttac
     8221 agatttaaaa tggcaagcaa tcaacttatt tataattata aagatgatga actttttgat
     8281 tttatttatg aaaatgagta ctatgaccaa gcacacttta taaaagaatt taaaaaattt
     8341 tcagggacgt caccaattaa atttagtggt gagaataaga cgattaaaga aaatataaag
     8401 tacagctatt tataattata ctgtcgattt tttacaatac ctccaattta ttttttgata
     8461 tgatatagga aaataaattg gaggttttac atatgaaaat tattacagaa atagttgagt
     8521 ttaatgtgga agaaaattta tcaaaagaag agtttataga aattgtaaat gacttagaat
     8581 taaaatttca ttctattcaa tctggtttta ttgatactga gcttttatat gatgaaaagt
     8641 ctcaaaagtg gattatgata caacattggg aatctataga agacctcaag agtgtttcta
     8701 gtaaaatgtt taaagattct tcaactgaga aatttagaaa agctttaaag aatcaaactg
     8761 ttaagatgaa tataatacca caaattaaaa gttggaaatt atagaactga atgtaaaaga
     8821 tagttaaata gtatcaaact aaattagcca aataacattt tgtatttaaa ttgttatttg
     8881 gcttttagtg tttattttaa tatgagtgtt atatactaga aaaaccaaca aactgttaga
     8941 gtgtggatta tcataatgtc atattcggga gctaaaaggc ttaatactga tttgccaatt
     9001 ggtcaatcca tgcatgtcca tctggatatg ctgttattaa agcatttaca agccaatccc
     9061 tttgctcttg tgataatagt gggactgtta catcgaagtc tttttgataa ccaagcctat
     9121 ctatgtatat tgatttgcaa aacaaaacca cttcgggagc catatatggg atattatctg
     9181 atgttatcag tctggcctta tccatatctc ttataattct ttgattttgg gaaaaaagaa
     9241 attttccatc tttctgtgga ttatatatca attcaataaa atcgaactgt aactgttcgt
     9301 cacactgtat attcatttta tagttatcat cctcgacttt ttttaattca ataaatgagc
     9361 aatcaggctt aatcgcaaaa acacaaattt gctctatatg ttgcttgtta aggtcgataa
     9421 taggtcgtaa taaataatta cccaagggct catatatatc ccatccttga ttaagcatat
     9481 actgaatgct cttttcttta tctgtgtcag aaatccatat gtcaatatca ctgtgtgggc
     9541 gaatatgcat attcgcaaat aattctaggg catatccacc acatattgaa tatgaaaagc
     9601 cacaatcatt aaaaaagttt acacaatctt taattagttt gttcatagca acctcctttt
     9661 gcatgtactg aaataaatta aattttttaa aataccaact aaatgtttgt tttgtgtaaa
     9721 tataaaactg ccgatattaa ggcagtttta tatttactat ttagaaaatt tattaacaaa
     9781 tttttgatat tcacacatta tcttatcatt cataaaagaa atacccataa aagcagcttg
     9841 ctcaccaaac aaagtaaaac gttctatcat ctgttgtgga ttacctggat aaactgttgg
     9901 aatacaccat gtgtttagaa gaaaaccaaa catttgagca gcaatctctg gatttttaac
     9961 ttccatagaa ttatcttgat ttccttcttc aatcaatgct tttatccaag gcacaatatc
    10021 atttataatc tcatcaaact gcgtagctaa atacttagga ttacgcaata gtgatgatga
    10081 cattaaaaaa atgtcttgtt tattgtgctg ttcataagta tgaagcaacc tatattgtaa
    10141 tttttctaat gcggtctttc cttcatcatt ttttacctca tacccataaa atccatcatt
    10201 atacaaccga cttgtgattg ccttaattat ttcgtctttt gatttaaagt gatgataaat
    10261 agcacctctt gaaaggccat ctaaattatc tacaatgtct tgaatcgttg tctgctcata
    10321 ccctttttct aagaataact tatgtgaaat atcaagtatt ttttgtatag tattatcagg
    10381 ttcttttttt cttcccaaaa aactcactcc tcgaaacaat catttggtat gtttatctta
    10441 gcaaatacat aatgatttgt caatgtgtct ttttagcatg ttgaacaggt atattgccat
    10501 gctttcatta ttttattttt ttgccttata ctggactata tttgcagttt cctaatatat
    10561 ttggctcata tttaaatacc attatctaaa agcactattg ctgtacgaga ggcaataggc
    10621 attttagaag aaggaggagt tgagctaaag tatacatcat aatctcttaa gttttctttt
    10681 tttgtgtttc ctccaaactc taccatatca gtatttaata tcgttttgta gtttgtattt
    10741 tgaaactttg aaatatcaac tgattgtatt agattagggt ggaaattaaa tataaataaa
    10801 tatttgccct tactgtacac caaaatcttt ttatcattat ccatatgtat aagttcatga
    10861 ctattttgga taaaaatatc actgtatttt gtaagttcga gcatagattt atcaaaattt
    10921 aataattgtt tatactttaa gttgttatct tctgaaaggc tccattgtct tctggcatac
    10981 ttatagctcc aattgttgcc ttctcgtgga aaatcaatcc actcaggatg tccaaattca
    11041 tttcccataa aatttagata tccttcacct gctagagaaa aagttattaa tttaattaat
    11101 ttaataagag atattgctct attgataaca tggttatttg agtttatttc catattccag
    11161 tacatttcct tgtcagctag ccaaaaaata attgttttat cgccaactaa tgcttggtca
    11221 tgggattcac aatatcctat atttttttct ccaggtcgtc tagtagtaag ttcataccac
    11281 attttgccca aatcccagtc ttcatcagat aagttagaga tagtttttat ccaaaaatca
    11341 ggtactccca ttgcgagtct atagtcaaat ccaattccgc cgtcttttat agggatacac
    11401 ataccaggca ttccactcat atcttctgca atacttatcg aattaggttt aatttctttc
    11461 attaattcat ttgcaaattg gagatatgtt atagcttcaa tatctgtatt catactaaaa
    11521 tatttttcat aactatcaaa tgaaactcca agaccatggt tatgatataa cattgaagtt
    11581 acaccatcaa acctaaagcc atcaaaatgg tactcattta accaaaattt tatatttgaa
    11641 agcaaaaaat gtattacttc aggtttacca tagttaaaaa gttttgtacc ccaagcagga
    11701 tgatttccct ttgaacctga gtggaaaaat tgatgttcac ttccatcaaa ctcatttatt
    11761 ccttctaaag tattctttac agcatgagaa tgaactaaat ctaataaaac agcaatcccc
    11821 attgaatgag cagtgtttat gaggtttttt aagtcttcag gagtaccaaa cctagatgag
    11881 attgcataaa agtttgaaac ttggtatcca aaagatgcat aatatggatg ttccataata
    11941 gccataagct gaatggtatt gtatccagct ttttttatct taggaagtat tttttcagta
    12001 aattcattat aagttccaat agattcgctt tcagtagaca tacctatatg acattcatag
    12061 attagtggag aagttatgtt ttttaagtca aaatcattgt cagtccagat aaatggagtt
    12121 tttggttgcc atatttgtcc attaaatcca ccaaaatctt tttgaattac tctttttata
    12181 tataatggta tacggtcaaa tgtttttcca tttgcagtaa cttgtacctt tacctctgat
    12241 ttgtgaggta agctattttg accaggaata aatatttccc aattaccaga cccaattttt
    12301 cttagaggat gagattttct attccaatta ttaaagtcac caattagtga caaactatct
    12361 gcatttggag cccattccct atagaagaat ccatcatttg tctgatgaaa tccatagtaa
    12421 agatgagcat ttgcaaaaga actaaaatct ttatagtttt tcaatgtttt tgatttcata
    12481 tcctcataat gtttcattcg cttttttata tcagattcaa atggttgtag gtatacatca
    12541 atatctaaaa ttttaaatct tttttgactt ttcattgtat ttctcctcca taataaatat
    12601 tacatctaaa aaataatatt tatctcatac tatcttctct gtataattga tatatattat
    12661 ataatcctaa taaaaagctt aagccaccaa tgattaattt cataatttac ctccctagta
    12721 tttatactta tatatcgtat tcatcaaaat ttaaaagttt gtttaaaact cttttaataa
    12781 tatcataatc aaagccttta taggaaagat gttgagaaat tttttgatat attttctttt
    12841 tatcttcttt ctttactctt tcataccttt tttttgctag atacatagca ttttcaaatt
    12901 cagtgtcctt gtctaattca gatactgctt cattgattgt acttctattg atacctttat
    12961 tatataaatt ctgcttaatt ctgtttttgc cacatttatt taggttaaca tttgtgttaa
    13021 caattttttg agctaataca ctgtcattta cgagattata acttttaaga aaatctatga
    13081 ccctctcaat tatattttca tcaaattctg atgatagttt ttcttttaat tttttttcag
    13141 attggtcagc atgagataaa atatttaatg ctttattttt agcttttata tacatttcat
    13201 catctaaaat aggttttaat tcttcttcat ttatttcatt cccttttttt aaattaaatg
    13261 tataaaccag ttctttaaat atagcaataa aaaatttatc atctacataa atattaactc
    13321 tatcatcatt tcttttttgt tgttctattt ttgtaattat acccataagt cctccttttt
    13381 tatatgtaat tatattaaca aaagcaacta ataaaattta acaaaaaact tatatttgta
    13441 tgttatattt tatcaaaatt aagacaaaat agtaaaaagt tatttttatt aaaaagtaaa
    13501 gcagaattat gttaaataat tattttttaa agtgtttttt agcatataaa tataattata
    13561 tacccaaaaa aacaaattat aagctttaag aaataaaaaa taatggtaca atagtattat
    13621 aacattaaaa ggagacaaaa tatgagaagt gaaaatctag ttaagatggc agagttgaaa
    13681 aatactgaaa aactagagaa atttaatcgc cataaaggca aaatcaaaat aggtatattg
    13741 ggaggtactt ttgaccctat acactatgct catttagcaa cagcagaatt tattagagac
    13801 aagtatgaca ttgacaaaat aatctttata ccatcaggaa atccaccaca taaattatgt
    13861 atcactacag ataagtatga tagatataat atgacacttc tagcaactga aagcaacgaa
    13921 gattttttag tttcaaaagt agaaatcgaa agaaagaaaa ggacttatac aatagataca
    13981 ttaaaatact taaagaaaaa atacaaaaat gcagacattt attttataac aggtgcagat
    14041 gcaatttgta gtgttgaaga gtggaaagat gtaaagaaaa actttgagtt agctactttt
    14101 atagccgcaa ctagaccagg aattagtttg ttaaggtcac aagagactat agaaaaacta
    14161 actaagaagt ataatgctga cattataaca gtttatgttc catcactgga tatatcgtcc
    14221 acatatataa gggaacagct aaatgaaggc aagtcaatac gttacttagt acccgaaaat
    14281 gtagaaaatt atttatatga aaataaacta tatcaatatg gagatgatta aatgaactta
    14341 gaaaatatta accaaagact aaatcaaatg ctaccagtgg ggaggcttag ccattcaaaa
    14401 aatgttgcaa aatgtgctga aaaattatgt gagatttatg gatgtgacaa agaaaaagct
    14461 tacttagcag gaatgattca tgattgtgca aagtatttaa gtgacaagga aatagaggat
    14521 tatgtaaata agtatgaaat atatttagac ccaatagagg atggaaatcg ttccttgtct
    14581 catagtgtaa ttggggcgta catatgcgag tatgaatttg aagtggaaga tgaagatatt
    14641 ataaatgcaa tcaaatatca tacaacaggg agagaggaca tgtctctttt agaaaaaata
    14701 atttacatag ctgatttaat tgaagaagga agaaaattcc cagttgtaga tacattaaga
    14761 gaattagcat atggagggaa gcttgatgaa gcacttttaa cttcttttaa taatacttta
    14821 atgtttgtca tcaataaaaa agaagagata catccaagaa cagttatggc aagaaactat
    14881 ctaattaaag aaaagttatt ataaaaaagc tatataaagg caaacatatt aataaattta
    14941 aatttgacta tgttacaaaa tcgtattaat atgttacaat aactaagtgt attttaatta
    15001 ggaaagtgag gaatttttat atgacagtgg aacaaatgac aaaaatagca tatgatgcca
    15061 tagaagataa actgggtcaa gatacagtta taataaatat aggaaaagtt tctagtttgt
    15121 gtgattattt tattattact acagcatctt ctcagagaca ggtaaaagct attgctgaca
    15181 atgtggaaga tgaattagca aaactaggat tagagccaag aggtaaagaa ggacaaggaa
    15241 ctcaaacttg ggtactcctt gattatggag acataatggt tcatgtattt aatgaggaaa
    15301 atagagggtt ttataattta gaaaaattat ggaaagatgc accttatata gatattgaca
    15361 cattagcata aacatgataa tatatgttat tataattaga aaatttcaaa aattatatta
    15421 aattgaatag actagagcag taaaagatta tattttttca gagagttagt ggaaggtgag
    15481 aactaatatt atataacttt gaacttacta gattaaaatc tattctccat ggctggatta
    15541 aaagctatct aagagagtct atatatgtag taggctaatt agggtggtac cgcgaagatt
    15601 tatcctcgtc cctaaacgta agtttagtga cgaggatttt ttattttcaa agaattattt
    15661 ggaaattata agtaaataat actaaataag gtagttatac acaattaaaa ataggaggca
    15721 aaatatgagc gtatataatt ttaaagaagt agaatcgaaa tggcaaaaaa tctggaaaga
    15781 taataatcag tataaaatgg atactgcaca aactgaaaaa cctaattatt acacattaga
    15841 aatgttccct tatccatctg gaaaaataca catgggacat gttagaaatt attctatagg
    15901 tgatgttgtc gcaagattca aaaaaatgga aggatataat gtacttcatc caatgggatg
    15961 ggattctttt ggattaccag ctgaaaatgc agctataaaa catggaatac atccacataa
    16021 atggacaatg gaaaatatag aagaaatgaa agagcaatta aatttattag gtattagtta
    16081 tgattgggat aaagaagttg caacttcaac gccagaatac tatagattta cacaagaaat
    16141 atttttgaag tttttagagc atgggcttgc atataagaaa aaatcatatg ttaactggtg
    16201 tccttcttgt gagactgttc ttgcaaatga gcaagttgtt caaggagcat gtgagagatg
    16261 taaagcaaca gtattaaaga aagatttaga acaatggtat tttaagacta ctgaatttgc
    16321 agaagaatta cttaatgact tagatatatt agatggatgg ccagaaaaag ttaaaacaat
    16381 gcaaaaaaat tggataggta aaagtacagg agcagattta gtttttgata tagatggaac
    16441 tgataaatct atgacagtat ttacaactag accagacaca acttatggag ttacttatat
    16501 ggtacttgct ccagagcatg aattagttaa agaattggtt gcagggactg aatatgaagc
    16561 agatgttgaa gcttttgttc aaaaaatgca tactatgaca gaaatagaaa gaacagcagc
    16621 tgatgtagaa aaagaaggaa tgtttatagg tagatatgtt ataaatcctt taaatggcaa
    16681 gaaagttcct ctatggatag ctaactatgt attagttgag tatggaacag gtgctataat
    16741 ggcagttcca gcacatgatg aaagagatag agattttgct gaaaaatata atttagacat
    16801 aattgatgta ataacagaag ataacaaaat gataaattca gaagaattta atggattaga
    16861 tgcttcagaa ggatttgaag gaataatcga taagttagaa aaagaaggta gaggaaagag
    16921 aacaattaat tatagactta gagactggtt agtttcaaga caaagatact ggggttgtcc
    16981 tatacctgtg gtttattgtg atgaatgtgg aatagttcca gttaaaaagg aagatttacc
    17041 agttctttta ccaacagatg ttgaatttac tggaaaaggg gaatctccac ttacgacttc
    17101 aaagcaattt atgtcaacaa cttgtcctca ctgtggaaaa ccagctagaa gggaagttga
    17161 tactatggat acattcgttg attcttcttg gtatttctta agatatgtgg atagcaataa
    17221 tgaaaatgaa ccatttagta aggaattagt taatagatgg catccagtag accaatatat
    17281 aggtggagta gaacatgcta taatgcattt actttatgca agatggtttg taaaggcatt
    17341 taagagtatg ggaatggtag acttcaatga gccatttaaa aacttactta ctcaaggaat
    17401 ggtacttatg gatggttcta aaatgagtaa gtctaaaggg aatacagtat ctcctatgga
    17461 tataatagat gagtatggag cagatactgc aagacttttc gtattatttg cagcaccacc
    17521 agaaagagat ttggactggt cagagcaagg tgttgatgga tgctttagat tcttaaatag
    17581 ggtttataga ttggttgacg agttagcaga tgtggttaaa aaggatgtag agtttggaga
    17641 attaaattcc caagataagg atatgagata tactatacac tctacactta aaaaagttac
    17701 tgctgattta agtgaaaaat tcggatttaa tactgctata tcagctctta tggaattaat
    17761 aaatgatatg tataaatata aagagttaga taatataaac gaagcagtta taaaagaagg
    17821 tgtacaaact atagtaacta taattgcacc atttgcccct catttaggtg aagaactatg
    17881 gactatgata ggtaaagaag gaagtgtatt tgacatagac tggcctaaat atgacgaaaa
    17941 agctttagta aaagatgaaa tagaagttgt tgtacaagtt aatggaaaag ttagaggaaa
    18001 attaactgtt aactcaaata tatctaaaga tgagatggaa aaggtagctt tagaagatga
    18061 aaaaataaaa ggattagttg aaggtaaaac tatagttaaa gttgtagctg tacctaaaaa
    18121 actagtaaat atagttgtta aataactcaa aaatatgaac aaaaatataa atttataaaa
    18181 taaacgaggc tgtctcaaaa tagagataag ccttttttca ttgttgaaat tataaaattg
    18241 ttgaaattat aaaaatagat ttgattttat acaaaaaaat gattaaagaa ctaaaaagtt
    18301 cattcttata taccctagtt gttgttttaa atattattat aattaatgtt aaatcgagtt
    18361 aatgtattaa gtggtatgta aatcattcag tttccaaagt gttgttcatc aaggaactgc
    18421 tctaagctta aacgaaaaaa atataattat tgtattttga aatttttttc tatataatga
    18481 aaacaggcaa aaaaggtgcg tatctatgct ttatatgaaa cacccagaca acgaaattca
    18541 gattcatata atagctacca tgtttctaaa aaggaacttg taaaaaagat agcgtttcaa
    18601 cttcccagtt gattaaaatt atcagcagga aaacaagtat ggtcagcagt ggtattctaa
    18661 tgggtgttgt cgatatatcc aagttgggat tgtctgagga tgttatcaaa taacttgtga
    18721 taggtgcagt agatgtggag attcctgata cggatttatt ctcaggggat ggttgcttcg
    18781 ggagatatgg agcgtaacca gtttattgat atggtaacca ttttttgtct aatttgatga
    18841 aagaatccca agaataccat acagaagtaa gacaggaatt aactggtggt ataaactgat
    18901 aaaggcaaat ttaaaaattt tgataggatg attttaagat ttatcttcta ttttgtgttt
    18961 tagaaataat tgaaatgtta tgaggaggta tgtacaaatg gagactgtaa caaataatca
    19021 atcaggtgta gaaattcaac tcagtctgtt tgaagctatc aaagatttat tgttaattaa
    19081 tcctattttc ttgttgggaa ttatcttgat tggtattttc ttagttgtaa tattcaagaa
    19141 aaatagtgat attccaaagg taaaaacatc tattttatca ctggcaatgt attactactt
    19201 atgtttaaca ctatcgcata ttgttggtat ccctacattc agtgaatata taagactgtc
    19261 acagttaggg gaaacgttct ttaatccaaa cataaatctt attcctttta gtgatggatt
    19321 tagtttgagt tttattttga atattttact ttttgtccca ttaggttttt tatgtccgct
    19381 tatcagcaaa acctttgaac gtttgagaaa tacattcttg attggttttg gattatctct
    19441 ttttatcgaa actattcagc tttttacgtt acacagagca accgatatag acgacttact
    19501 cacgaatgta attggaacaa taataggcta tttctgcttc aaactgattg ctaaattgcg
    19561 aattgtaaaa ctacattcag atgatgactc tatggaacag gattacacag tatgtattcc
    19621 gattgccatt ataatagttg cccttatatt aggatttttt agttaagttc caaatagcta
    19681 atttgggaat tatggaggtc attaagtgaa taaaattact tttatatgtt taggtgtaaa
    19741 aagtatggag aagtcaatta aattttatag agatggatta ggattttaga ttacaaactt
    19801 ttagtttacc aaggagatag caaagttgtg tgccaaaggg taaccatttg gaaatccaga
    19861 caacataaca gatagtacgt taccttttac aggagcatac tatctgttat attgtcaaca
    19921 tcctatttta tggtttgtgt gtagtttcct gtaaactgaa ctaaataatt aaatagaagc
    19981 tattagaatt aataataaca gatagatatt aataagcata aacaaatagt aaaatgtgta
    20041 gatatagacg tttttaagtg aaactattat aaaataattg actgataatc aactgacaaa
    20101 acctattttt ttaggtttaa ctgacattta actgacagtc agtttttact atttaaatag
    20161 aagttcgctt agattgtcgg aagcttcttt gtccatttct ttaagtacat gagaatatct
    20221 attcatagtt atttttatat ctgtatgacc caatctttca gaaacaactt tcatattagt
    20281 tccccctaaa agcagcagag tggcacttgt atatcttaaa tcatgtattc taatcttttt
    20341 taaattattt tttttgtaaa attgtgaaac gtttttctta gtgaagaagg tagaaacgga
    20401 tttaaattgg tgtttagaca aactaaatta tttctgtttt ccaggatacc ttacaatttt
    20461 aatttgcttt gtcttagttt tttaattttc aatttttcaa ttaattcttt tggagctgat
    20521 aaagctcttt ttgattttgg tgtttttggc tctttaaaag atattttgcc attagaatag
    20581 acaagaattt gattaacatt tatcagattg ttatctaagt caacatctga ccacctaagc
    20641 ccagtagctt ctcccattct taaacctaga agtaacatta aaagaatagg tatttctata
    20701 ttattactaa gtaacttttc tattagcaat aatacttctt ttctattgta tatttcattt
    20761 gtagaatatt tttctttaga aggaagtttt ataaaatcac atgaattttc ttgtatttct
    20821 cttaatctat atgcttccct tattacagaa cttagaaagc tataccttac tttagcacta
    20881 gtaaaggtag aattattaaa gttataattt acaaaagctt gtactgaact aggatttact
    20941 tctgtgagtt ttagattctt aaaaagaggt tctatgtaat ttttaaccca agattttgta
    21001 tttgtaacag tatatggaga ccaattattt ttattcatgt ccatgtattt ataacatctt
    21061 tctacaaatg tcatatcttt tggagcaaca aacttattat tgtttatagt agattttatt
    21121 tcaattaaat gtttttcagc atcctttttc ttttcataac ttccataact tttctgtttt
    21181 atcttgccag ttgtttcctc tatgtactcc acatatacat agaatttttc ccctcttttt
    21241 cttataaaag ctgatttgat attcatatat gtacgctccc tttataagtt agttttataa
    21301 aagaacagtt gtactactct aattatgtca ttatcttttt aattctttac agttacatta
    21361 taacacgtat ttgtatacac ttaaattaac aggaagataa atatcgttaa aggaggaaaa
    21421 gaaaatttaa tgtagaatta ttaagatata tagtatttca tatataaaag ggggagatat
    21481 tgtgaaatta aagaaattat tatcactagg gttagtgtca atgtttgttg ctggttttcc
    21541 tatatcagct aatgcacttg ataaaattga taaaattcaa ggagcagata aatacgaaac
    21601 tgctggtatc atagctgaca aacaaagtta tactactgca atacttataa atgcagatag
    21661 tacaatggct gatgggctaa gtgcgagtgg acttgcagga gcaacaaatg caccaatcct
    21721 tttgactaaa aagaataata tacctaatgc aactcttaaa agagtagaaa aagctaaaaa
    21781 ggtatacata ataggaggag aaagttccat tgataaagca acagaaactt ttctaaaaga
    21841 taaaggaata gagactagaa ggcttcaagg taatgatagg attaagacaa gttataatgt
    21901 agcaaaagaa ataaattcca ttaataaagt aaataaagta atattaacta acgctttcaa
    21961 aggtgagcca gatgctatga gtgctgcacc tgtagcagtt agagataaag cagctatagt
    22021 attaactgat ggaaaaagtg ttccatttaa tacaactggt atagaaagtt atgcaatagg
    22081 tggcacttca tcaatgagtg atagtttagt aaatgatact aattcaactc gattgggtgg
    22141 agtagataga tatgatacta ataaaaaaat agtaaataag ttctataatg gcgcaaaaga
    22201 attttatata gctagtggta ctgatttagt ttatgcttta gttgcttcac caatggctaa
    22261 aaataatcct attgtactag ttgatattgg aagtaataaa gatatactta aaaatgctgc
    22321 aaaagtaacc gggataggaa atctaagtga taaaattatg ctagagtgtg aaaataccat
    22381 caataatatt agtcttccat cttcaaataa aaatataata tgtggattaa agattgattt
    22441 tgattcaaat cacataattt ggcaagataa aggaagttat cttgaatgtt atgatgataa
    22501 ccttgaatat tatactgaaa aatataaaga cccaacagtt cctataaata tagaaaatac
    22561 aagtacacaa aatttagatg taacaaaatt aaaagtttat ggagaagcta attcaacatt
    22621 atatatgggg caatacgcta aaataaaaat ggattttaat agtttcggtg tattaaagcc
    22681 aggagaaaaa tgtactattt atttagatat aatttcatta gatccatcaa gaagcatgac
    22741 attaacattt tcttatgtag gtgataaaga aaattataaa tatgaacaag gattggcaag
    22801 tagaatatta ttttataacc cggatggaga agattttttt gaatataaat aactagtggg
    22861 tatgtaaatg tctcgatatt gctcatatgt tgagttatta tatttagttt catatgaact
    22921 atatggattt taaaattaaa aatacttaaa aacatttact ttaatagtag gtgttttttt
    22981 gattaaaaga atattattat aatgtaaaaa gtaataaata ggtaaaatat gtaagaatta
    23041 tatgttataa tatttttagc aagaagatgt aatctacaat ttatagagtg gagttcatgt
    23101 atcaaaaaat tatcctcccg acgttaagaa gggaggtgaa tatacatgga taatttttta
    23161 caaggcatac tagcaagtct atctgctagc ttaatagttt atatagctag caaactattt
    23221 agaaagcgta aaaaaccact caaagcggca actaagagtg gttgggaatt tgatttaaaa
    23281 atcagattcc ataaaactaa gtaatttcta aattatgaac tccactctac agcaaaatag
    23341 attgtagttc ttcttgcttt tattatatca caaattggta cagatattca aaaataatat
    23401 ttttatgata taataaagtc atagaaattt tgcagtgttc gattttttga agaaattaag
    23461 gcttaacagt tgaaatataa ggcattgagg acttgtgata agtgttatca attgcactac
    23521 tcatggttca ctgcaaattt gagagatttg tatatgtgta ggcattggaa atactcaatt
    23581 tattttgggg ttttatatta actatatgga atgtaaattt catattccat gcattctgct
    23641 tacacttaat agaaaagttt tatattaact atatggaatg taaattattt ctagcgactt
    23701 ggtcggttgc tccatttagc ttgttttata ttaactatat ggaatgtaaa ttttttcaaa
    23761 tctgatatat cgaccttaaa tttcgtgggt tttatattaa ctatatggaa tgtaaatgat
    23821 ataaactttg ggagttcaga agaaggatta aaaagtttta tattaactat atggaatgta
    23881 aattagagat gaactcagat agaaaaacat gtagatgtgt gttttatatt aactatatgg
    23941 aatgtaaatt cttcaacagt tgtgttacca tctcctacac gcacaggttt tatattaact
    24001 atatggaatg taaattgcta cgtaaccagt ttcaccgctt tcagtatata acgttttata
    24061 ttaactatat ggaatgtaaa ttgttggtat agtttcagaa aagaaattcg aaacacttgt
    24121 tttatattaa ctatatggaa tgtaaattgt atccaaaaaa ttacaataat catacgaact
    24181 gctaatataa gcagtcaata tatgtgtaca tttatctatt ttatctctaa atatataaat
    24241 tattatcccc ctaaaaaact ttcataaaaa caaaaagaac aatatctctt tggcaactgg
    24301 ctgacataac tcataagata tttatataag tcttagtctc tatagctttg cgtcactaga
    24361 tttctctagt tttgccgatt tagttttatt ctataactaa ataatacaat agaattagtt
    24421 attattcaat aagattgttt gaaaattgaa taaatttata ggtatgaacg taatttcaca
    24481 cttaaaaaac agactaaata cgtagaatat atagaaaaat ttacctgtag tttttgtgat
    24541 aaaaagctcc tattattaat ttaagctaga taagtttgag gaagtgacat aaattgaaag
    24601 aaggaatata ttatgttgaa taaaaaatta ccagatgcag aattaaaaat tatgaaatac
    24661 atatagaata ctggttataa aactgtaata tcaaaagatg ttgcagatga aatagaaaaa
    24721 acatatgctt ggaagcatac aactacaatt acacttttag ctagattaac taaaaaaggt
    24781 tttttcatat cgcagagaat tgggaaacat gtacactata gagtattaat aaaagagaaa
    24841 gaatatctca aaatagaggg aaaaagaatt tttggaggtc tacataacaa tccattatca
    24901 gaattaattt caaaattgca tgatggagaa gaaataactg aagaaaaaat aatagaaata
    24961 ggaaattgga taaaaagctg gaaagatgaa gattaataaa taaaaggtag ctactaatat
    25021 aagtgctacc ttttttcttg tggataatat tggggataag ttgtggaaaa cttgtggata
    25081 aaatattttg ctgacattta actgacataa gtattagatt ttgatttaaa aatgttgaaa
    25141 tatcaataaa taattaaata gaagttatta gaattaacaa tagattcctt tttcaaagaa
    25201 atctttgatt tcatcaaggt tatcagtttt tccaagtgct aagataagtt ttattctagc
    25261 tttttgacct ggtaagtccc caccaaatat acaaccaaga ttttttaaat ctctaccaga
    25321 accaaagtaa ccataactat cgaatactct acctgaatga catctagaaa ctataactac
    25381 aggaagtcct ttttctctag catattcaac tccagaaagc atttgaggag gaatattacc
    25441 tctacccatt gcctcaataa ctataccttt ataaccacta tcaacagcaa atcttataaa
    25501 gtcagcattt tctcctacat atgctttaaa taaggcaact ttagattcta ccttatcagt
    25561 atctataatt gttctattta caatatctct tgtaaggaca agttcgttgc agtcaattat
    25621 tcctaatggg ccactagtta gagatttaaa tgtatttaga gaaagagtat ttgttttagt
    25681 agcttcagaa gctaataata cttcattgtt taaaactaca aggactcctt ttcccatagc
    25741 atctttggat actgcagtac aaactgatgc agataaatta cttgaaccat catatccaag
    25801 ttcagaacta cttctcatag cacctgtgac tattacaggt ttgatgttgt caattgtaag
    25861 gtctagaaaa taagctgttt cctctaaact atctgtacca tgtgttatta caacacctgt
    25921 aatatctttt cttgctaata aatcatttac ataatttttc aattccatca ttctataagg
    25981 tgttatgtga ggtcctggaa tttcatcaaa attaaaaact tcaacatctg caactttatc
    26041 aatgttggta accattgata gtatttgttc acctgataaa gttggtatag ctgctccgac
    26101 tttatcatct actgtcatag atatagttcc accagtaaaa actatggcaa cttttttctt
    26161 aatactcata ctattctctg cctttcataa ataaaattta taattccgat aggattatat
    26221 caaaaaaagt agttaaggtc tacataaact cttttattca tataatttag atatttcagt
    26281 gtaatataat tatttcttaa ttttttgcca ttcaacgata taaccattta atatctctct
    26341 tatggctttt cctatcttag tataagcttc atcatataga tttgctagag atattctaat
    26401 tgaccattca ggaccataga atccatttcc actaagtaaa actactgaat agtcattagc
    26461 taatttataa agaacatcta ctggagatgc agttttactt ataaatttaa ataagtcttc
    26521 tccgtagttt aatttagccc attcttcaat atcaaattga gtgtaatatg cagcattgtt
    26581 tttgttttca ttaattggaa gctctaaagc ttcaaataat agtttttgac gtctatggca
    26641 gatactcata ttgagttttt tgtaggcatc tactttgtca atcaatgcaa aagcagagaa
    26701 aaacgccatt tgtacttgct gtggagtaga aagaccagca gtatggttga gagcaacaag
    26761 tctgctatca gcaacaactc tttccataaa tgaaaggcta gaagggttaa gactcatatc
    26821 actgtaacgc ttatctactg atttttttaa ttctccagtt aaatcattta ttttcttatc
    26881 aaaaacattt ttcttatgaa gggcaaatgt accaagtctc catcctgtaa ctccaaaata
    26941 ttttgaataa gaatatactc caacagtgtt gtaaggtagt tttgacatta aggatgaaaa
    27001 atcttctaca aaagttccat atacatcatc tgatattatc attaaatctt tattataatt
    27061 ttcaattaca tctattagat tattacaaga tgtttcatcc atagctatag aagcaggatt
    27121 attaggatta acaacgaata aagctttaat agatttgtca cgaagtttct ctaattcttt
    27181 ttttgtatat tgccatgtat gagcaccttt ttcatcaact tcattagcat ttatatttac
    27241 cactttaaag tcgtaacgag gaaggttagg tatttcaaga taaggtgtaa atattggagt
    27301 cattaaggct atggtatctc ctttttttag aagttcattt gccattaatg aatcaaatat
    27361 atagcacata gcagctgtag caccttcaac agcaaaaatt tctacatcac catatttacc
    27421 tgatatatca tatttcattt cttgaactag gtaatcgtgt actatttttt ccatatgagg
    27481 taacattcta tctggaagtg gatagttatc accaataatt ccatcagcta gttcatgaac
    27541 aaattcatct ccatcaaatc caagttcatt tataccaaag tttataatat ctctagctaa
    27601 atatgctcca ggcatatcta tattttcatt tataaattta aaaaatcttt ctttaatacc
    27661 ctttttttga ggcattccag ccaaatgacc taaatcccaa ttagaacgag tttcagtaat
    27721 agcgaaatga ccaaaagtaa aaaaggcttc tctagcagtt gaacaagtcc agtttggatt
    27781 tccacgacct gcatcaagta attctctgtt attttctttt gcagtgtatt ttgcaatatc
    27841 tattaatttg tccttaaatt caaaagggct tatttttcca tatatgtttt tgatttcttt
    27901 ataagtatga tttttcatgt taaattcctc cttatgtaat aagtttcaca tttttataat
    27961 aaaataaaca agttgcaaaa atgattatac tttaattata ataggtttat agaaaaagta
    28021 aagtatgaaa ttaaaataat aactctattt agccttatta aatatatgtt aaaataaaaa
    28081 atacctttta ataaaaaatg attgttatat aaaataaata ttcaatttaa ttatcacctt
    28141 agttttttta ttgtatttta ttatatatgt atagttttct aattttgaat aaaaataaag
    28201 taaaactttc ttttatattg aagttgttta gtaagacatg tattttatta atttattaat
    28261 cttaataatg ttaaataaaa tcaaaaaaat agattttggg taaataaaat aatataaaat
    28321 ataaatttta ataaaaataa taaagtatat attattgctt taataagaat gtaaaaaata
    28381 tttttaaatt atcatttaat gtaatttaaa tgaattgaag atatatgttt attgtatgca
    28441 attgttgtat ttttaggttt tttgtgatta attaaaaaat tataaaaatc gtttacatgt
    28501 tgatttttaa aaaaaaaaga tatagaatta tatagaaagt aataaacaaa aattggattt
    28561 acgggagtgg aatgaaatga tgaatgttac cttaacagat gtgaaagagg ctagagagac
    28621 cattaagaac atagtaaaaa gaactgactt acttgaaagt gttaaactta gcgaaaaaac
    28681 aggagcaaat gtgttctata aatgtgagaa tcttcaaaaa acaggttctt ttaaattaag
    28741 aggagcttgt aacaaaatag cgagtttaac agatgaagaa aaggcaaatg gagttatagc
    28801 ttcaagtgca gggaatcatg ctcaaggagt tgcattggga gcaaaaatga ctggtataaa
    28861 atctacaata gtaatgccag caactgcgcc tttagcaaaa gttagtgcaa ctaaaggtta
    28921 tggagcagaa gtagttttaa atggtgcggt ttatgatgat gcatatgcaa aagctgttga
    28981 aatacaaaaa gaaacaggag caactttctt acatccattc aatgataagt atgttatagc
    29041 aggacaagga actatatctc ttgaaatttt cgaacaatta gacaataaag ttgatactat
    29101 actatgccca gttggtggag gaggaatcat ctctggtgtt gctgttgcag caaaagcatt
    29161 aaatcctaat gtaaaaatag tcggtgttca aactgcaaat ataccttcaa tgaaagagtc
    29221 aataaaaaat ggaaaagtaa caacagcatt taatgatact acaatagctg atggtatagc
    29281 tgttaaaact ccaggagatt taacttttga aataataaat gaattggttg atgaaatagt
    29341 agtggttgaa gagacagaaa ttgcagaatc aatattattt atgatggaaa gtcaaaaaat
    29401 agtttcagaa ggtgctggtg ctgtatgtac agctgctata ttaagtggta agtatgtacc
    29461 agcaaaagat gaaaatgtag tttgtataat atctggtggt aatatagaca taaatacgtt
    29521 atatagaata ataggtgttg ctttagctaa agaaggaaga agatattcat ttagtacaat
    29581 tatggaagat aagccaggaa actttgctga gttaactaga ataataagtg agaatggtgg
    29641 aaacatttta agtgctaatc aaggtaaatt atcagcaggg gaagctctag gaaaacaaag
    29701 tgcggaattt atattagaga caatagatta tgaccatata gctagaataa agaaagctat
    29761 agaagaaaaa ggttttaaaa ttatagaatt ataataaaaa gtgtatataa tatacaagaa
    29821 aaatagtata atagtgtatg aagatacatt ttatgtgtat tagattaacg aattaggagg
    29881 attttaaaat gaaacatgaa gtaatacata ctaatgatgc accagcagct ttaggaccat
    29941 attctcaagc tataaaagct ggaaacttgt tatttgtatc tggacaagtt cctcttgtac
    30001 cagagactat ggaagtagtt gaaggagatg tacaagctca aactgctcaa tctttaaaaa
    30061 atcttaaagc tatattagct gaaagtggag ctgatttttc aaatgtagtt aagactacag
    30121 tatttataaa agatatgaat gaatttgggg ctataaacga agtttatgct gaatattttg
    30181 gagaaaataa accagcaaga gcttgtgtag aagttgctag attaccaaaa gacgttaaag
    30241 ttgaaataga agtaatagct gtattataaa aatacaatat ttttaatttg aaaaggctga
    30301 aaaactatat tctagtgatt cagccttttt ataaaaaaat aaatcacaat aaagaacatg
    30361 ataaatattg tcgaattaaa aaataaaatt aaaataaata ttgcaatatt tttgagaagg
    30421 ttttataatg agtatataat ttgaaacgtg taactattaa attaggcatg agttcttgga
    30481 tatttttatc ctgaggattc atgccttttt tgtattgaaa ttcaaaaatc tatttaataa
    30541 ggaggaagta ctgtgttaaa ttttttcaag aaaaataaaa gctataagtt acatgcagta
    30601 gtgagtggta acagcattaa tattgagaaa gtaaacgatt ctgtgttttc aaaaaagtta
    30661 atgggagatg gagttgcaat tattcctaat agtaatgttg ttgtagcccc ttgtaatggt
    30721 aaagtaactg tgcttacaga atcaaagcat gcctttggta tggtctcaga tgagggtgtt
    30781 gaaatattag tccacatagg aattgataca gttagtttac agggtgaggg gtttaaaaat
    30841 gaagtgtctc aaggagatac tgttaaaaaa ggtagtccaa taataagttt tgaaagagaa
    30901 aaaataaatt ctcagggaat tgattgtaca acaataataa ttgtattaaa tcatagcgaa
    30961 ttttcagaaa taaattgcat ggtagaaaat gaagttgttg cagggcaaga tactgttatt
    31021 gaaattatga aataatagga agggattaat tcaatatgag agtagtaaaa atctttaata
    31081 ataatgcatt atctacagta actaatgata ggaaagaagc tattttacta ggtcttggta
    31141 taggttttaa taaacgtcca ggagataaag ttaatgaaga taaaatagaa aagatttatt
    31201 atgttcaaga ccacatgcaa acaaaatttt tagaattatt aaaaaatgtt agtccagaag
    31261 tgatggatgc ttcacaacaa attataagtc ttataccagg aaatgaggga aaatttaata
    31321 ataaagggat attatcttta gtggaacata ttagttttgc aatagataga atgaaaaata
    31381 atgttttttt acctaattta atgcttttgg atataaagat gatgtattca aaagagtttg
    31441 aattaggagt aaaagcttta gaaattatat atagagtatg tcatatccat ttgcctgaag
    31501 atgaagcagg ttacatagct ttacattttg tcaatttaca atcaaatgat aatttggcat
    31561 atgatacttt aaaatttgta aaaggtagta ttgatttgat taaagaatgt tatggattag
    31621 aattagatga atcgagttta agtacattac gttttagaac tcatcttaaa tttcttgctc
    31681 aaagaatttt taagaatgaa atttgtcagg atgataaaat gattgaaatg tatgattatt
    31741 taattaacaa tcatcctaaa aataaagaat atttagaaaa gttaaatgta tatattgaaa
    31801 aggagtttag gtataaatta gataaacctg aaaaaattta tctactacta cacctaacaa
    31861 aaatcttata agaatgagat gaattagtaa tagaaatata taattttagg gggggataag
    31921 attgaaagaa aaactacttg gaggactgga aacatttgca aaggcaatgg ttcagccatt
    31981 aatgtattta tcgagtgcag gaatattaat ggtggtaggt gtactactta caaatgatat
    32041 gttattagga gtacttccat tttttaaatg ggagccaatt caaatatttg gaagcctaat
    32101 ttataactgt ataatggcta ttattaataa tcttgctgtt atatttgcta taggtattcc
    32161 tgctgcacta gcaaaaaaag agaagcacaa agcagcgtta ataggattta tgagttatat
    32221 aatatacctt acagcttcca acactatgtt aacatcacta ggtcaactag caaaagaaag
    32281 caagatgctt ggactgatag ggactggaca agctactatt ttaggtattc aagttgtaga
    32341 tacaagtgta tttggtggaa ttattttagg gtgtatagct ggatatgtat ttaatcgtac
    32401 aagcaacaaa acatttaaag gagctttaca gatatactcg ggagcaaatt ttagttttat
    32461 atgcatgttc tttgtatcca ttttaattgg agttgtgagt aactttatat ggccattagc
    32521 tcaacaagga atagcttctc ttgcaaatgt catcaaagat acaggtacat ttggtttatt
    32581 cttatatggt tttttagaga gaatattagt accaactgga cttcatcatt taatctatac
    32641 accatttcag ttttctgatt taggaggagt gcttaaagtt ggtgcagata cagtttcagg
    32701 agcctatgct atagttatga cagaaatgaa tttaccagtt gagcgtttct cagatagtat
    32761 atactacatg gcaactggat ttacaaagat gtttggttat ataggtatag gagctgcctt
    32821 tatttatact gcatataagc aaaataagaa gaaagttaag gcaacgatta ttccactaat
    32881 aattacggca gtattagcct ctgtaacaga accattagac tttatgtttg tattctgtgc
    32941 accattttta ttctttgtac atgcagttat agctggtctt tttatagctt tattaaaaat
    33001 atttgatgtt actgcattat gtggagggaa cttattagta tcaattataa tgaatactac
    33061 agtaggcgta gaaaaaacac actggccagt aatgatgata ttaggacttg cacaaattat
    33121 tgtatatttt gtagtattta gttttttaat taagaaattt aattataaaa ctccaggtcg
    33181 tgaagatgag agtacagcta caggcgaaga acaatcaaaa caacttaatt tagatgcagg
    33241 gatagaaaat ataattgatg ggttaggcgg aaaagaaaat attaatacag tagaaaattg
    33301 catcactaga ttacgtgtta atgtaaaaga tgaaagtaag attaatgaag atataattaa
    33361 tttaacgcca aatagcggga ttgtaaggaa aggaaaagat atacaaataa tttttggact
    33421 tcatgtgcat gaggtaagac gtgcagtaga agatttttta gaagcttatt aaagatatat
    33481 atttatatag caagggtaaa taacagcttt aagtgctgtt tactatttat taaagataca
    33541 tataatttat agaggaggaa taattattat gattattact attgttggtg gaggaagcac
    33601 atttactcca ggtattgtta agtcaattgc attaagagaa aaagagttag agcttgagga
    33661 aattcgctta tttgacattg ataaagaacg ccaagataaa gtagctgtag ttgtcaactg
    33721 gatactaaaa gaagatgtta aaacagatgt taaactaact gtaactaatt gtgaaaaaga
    33781 agcgtataca gatgctacat ttatatttgc acaaatgcgt gttggtaaat atgaaatgcg
    33841 tgagcaggat gaaaaaattc cattgaaata tggttgtgta ggtcaagaaa cttgtggttg
    33901 tggagggatg gcatacggac tgcgtacaat acaaccaatg ataaaggtta ttgatgatgt
    33961 agagaaatat gctaaaaaag attattggat attaaattac tctaatcctg ctgcaatcgt
    34021 ttctgaagct tgtcgtaagt taagaccaaa tgcaaggatt ataaatatct gtgatatgcc
    34081 aatagctatt atagatatga tagcggggtc attaaatatc aatgacgttc ataatatacg
    34141 ctatgattat tttggtctaa atcattttgg ctggtttact tcaatagatt ataaacatag
    34201 agacttaatg gaagagatta aggaatacat aaaagaaaat aaaatattat taccaaaatc
    34261 ttatatagaa aacttaaata aaagtcgtag tacaggaaat cgccatgctg taagtagctg
    34321 gatacatgtt tgggaatctg tttatacaat gttagaaagc ttcccaaaat atctgccaaa
    34381 cacttattta acatactatc ttttaagtaa agaaacagtg gaacattcaa acataaatcg
    34441 tactcgtgca aatgaggtta tggaaagccg tgaaaaagac ttatttgaag gtgtgagaca
    34501 ttacttagaa actggagaaa tttctgaaaa agcattttat gcaggttcac atggagattg
    34561 gattagtgat ttggcagttt caattaaaaa tgatacacgt agtcgttttt tagttataac
    34621 tgaaaatcgt ggagctatac caaacatgcc atatgatgca atggtagaaa ttccagcata
    34681 tattggtaaa gatggtccag aagttattgc tcgaggtcca atacctctat ttcaacaagg
    34741 attaatgatg caacaactta acagtgaaaa attgatagta gaagcttata tagaaaatag
    34801 ttatgaaaaa gctttacaag cattcacatt aaataaaact attccaagta tgaatgttgc
    34861 taaagaaatt ttggatgaaa tgatagaagt taataaggaa tactggccag aattaagata
    34921 gtaggataaa ggaaagggtt tttatttaat aattagatat gttttcagag tcttttatca
    34981 aaatgtattc acaaacatat ggcaatatat taaaataaag agtgatattt ttagaagaat
    35041 ggggtgatgc aatgaacatt ataaataaaa ttttttggga agaagatagg attggcatga
    35101 ttacaaataa tttagaggca gatacacata gccactgtat gttacaactg ttcttaggga
    35161 tagaagacag cattgaaata acagtcaatg aaaaattagt taaatgtaat tgtatcatag
    35221 tagataaaaa tatctctcat tcattttcag caagaaaaaa agtttattac tctgctatta
    35281 ttgaacctac atctatatat gcagaacagc ttacctcaaa aatgaatgat tttggctact
    35341 ggatatgtga caatgatgga ttagagaaat tacgtcaaca aggaactttt ttgatagata
    35401 actctagtaa agaacaatat ttaagattta tggaaatgct taataactat ttgaatatac
    35461 ctataactct caaacattat gatgacagaa ttactgaatt gctcaattta ttacgtactt
    35521 gtaattgtga taatcatact atttcaagtt ttgcagataa agtgtcccta tcagcaagta
    35581 gattatcaca tctgtttaaa gaacaaatag ggataccttt aaaaagctat atcttatttc
    35641 atcaaatgga gtgtgctttt agagaattac tttctgggaa aaatgttacc gaagcttcta
    35701 tgactgctgg attcgatact ccatcacact ttgcagggac agttaagcga atgatgggaa
    35761 tgcctgtttc tttatctttg aaagatagcg aatttttgaa agtatattaa atattctcgt
    35821 tatataatga agttgtacta agaaaggggc tttgttatga ataaagaata tttagaggaa
    35881 acaaaaatgt taaattataa tgaaccacaa cttaagcttt tggtatcatc aaagaattgg
    35941 ttggaattag atgattttca taaaataaaa tctatttatg agtttgtaca gaatgatatt
    36001 ttatttggat ataatgcttc tgatatgtta agcgcaacac aggtattaaa tgatggtatg
    36061 ggacaatgca atacaaaagc tactctttta atggcattat tacgtgcagt gaatatccct
    36121 tgtaggcttc atgcttttga tgtaacaaaa gattttcaac gaggagctac atccaaattg
    36181 atttcactat tagcaccaaa atatattctt catacttggg tagaggtatt ttatcaagat
    36241 aggtggattg ctcttgaggg tgtcataact gataaaaaat atttagaagc aattcagaag
    36301 aaatttttta atcatggtgg aacatttaaa aagtatgcaa tagctacaaa tgatttgaaa
    36361 aatacatcta ttgattggga tggtaaagat acttttatcc aaaaagaagc tatcgtgtat
    36421 gattatggta tttttccatc accagacgta tttttttcta ctcattcaca acatatgtca
    36481 aaattaaaaa atttcatata tgtacatctt atcagaaaaa taatgacaaa aaatgtatgt
    36541 aaggctagaa acaattatat tgataaaaac gaatgagtgt ttaagaggta actatatagg
    36601 aaatatatag aataattaaa actgtactgg ttaaaatgaa taaaaaggag ttatcacaga
    36661 gcaaacttaa attgttcata ggataactcc ttttctgtat taacttctaa taatttgatg
    36721 tctttttata aaacatatag atacaattaa accagtaaat gcaagagtag ctgctattga
    36781 aaatgcaaca tctattccat gaatgttaga cagcatgttt gaactcatat gagctttctt
    36841 agtagcactt gtcattatag taataagtat agcagaacct atagctccag atatctgacg
    36901 gagtgtgtta ttaattgctg tggcatgaga tataagttct ctatctaatg ttttaattcc
    36961 ccatgtagtt aatggcatta aaaccattga aataccaatc atacgaatac aatacatcaa
    37021 tgacacatga attaaagatg tatctctgcc taaaaaagcg aaggataaag ttcctaaaaa
    37081 caaacatcct gttcctaata ttgatagagc atgaggtcca tatttatcta aatgacgtcc
    37141 tgcaattgga ttgagtacaa ccatcaatat agcaccaggt aacattaatg aacctgaaga
    37201 taatgcagaa aatcctctta cagattgaac gtacagagga atcattaatg tagcagacat
    37261 cattgaggca tatacaatca taattaatat tgtagaaata agaaatggtt tatttttaaa
    37321 aaccctcaat tctaaaaaag gttctttaga ttttaattga cgcaatgtaa ataaaattaa
    37381 tgacataatt cctattaata ttggtaaata tgtggcaata ttagtccacc cataattacc
    37441 ttgattagta aatccaatta ataaaccacc aaaacctaga gatgatagta ctattgaagg
    37501 tatatctaat tttagttttt gagtttcccc aacatttctt aatagaataa atgatagtat
    37561 aacatctaat atagcaatag gggaaagaaa cagaaataaa ctatgccaac caaatgaatc
    37621 tactaaccat cctgataaag ttggacctat tgctggagca aatcctactg taataccaac
    37681 taaactcata gctgcaccac gtttttcctc agggcataaa tagagtataa taacttgtaa
    37741 aagtggcatt agagaaccag aacccattgc ctgcaacaca cgagcaatca acatagttga
    37801 aaaattatta gaaaaaagtg caataataca tcctatagaa aagatagaca ttgatgtaat
    37861 aaataacttt ctagtactaa atcgatttat taaataagct gttgtgggta caataatacc
    37921 tgcaataagt agataaattg ttgttaacca ctgaccaata tcagcagtaa ttttaaaatc
    37981 tgacattata ttaggtaatg ctgttgacaa tagtgtttga ctgagagaac ttataaaagc
    38041 accagtcatt acaattgcta ttattaaatt tcctttttta ttgttacttt gggtttccat
    38101 aatttataac gtctcctttt ttaattgatt tttaatgctg ttcaataaaa gtacttttgg
    38161 tcttaaagtg tcttcttttt ctaaatatgc aatcattgca tccataatta aagaatcata
    38221 ttgttgattt tttccttcga cgtataattt ttttattgct tctagtaatt taggattttc
    38281 aaggagagaa gtatcagttt tgattagttc ttctatatct tgtatcgttt taaaaaatag
    38341 cgatttatta tgaagggaaa agtaaacttc atcttcttgt ttatgtaaaa acattgattt
    38401 ttcaattaaa ggatttagat tatccatatt ttctacaact aaatctagaa tttgtatagt
    38461 aaatttggca ataaagtata catttatttc tcttttttgt acatgaataa tgtatataaa
    38521 ctgatgaatt agagcatcca ataagaaaac taaatcaaat ataatttttt ctattttatc
    38581 accatagtta tcaaataagc ttagtttgta ttcattcaat aagttagctc ttgattttgt
    38641 ttgcaattta cttgtagcct tacgttgctc ttcagaaaag ttttctctta tataggtatt
    38701 tatggtagtt ctagaaaaaa tatttttcca tacagcaatt atctttctgt ttaacttttc
    38761 tgatgatgga atgtcattat tttcatttat ggaatgtata atttctaaaa acttttcatc
    38821 ataataattg attatttcgc agataaaact ttccttagtt tcaaaatgct tgtaaaaagt
    38881 agctttagac attttacact cttttacaac atccgatatt gaagtatttt gaaaaccttt
    38941 ttggtcaaaa attttttgtg caatagttat aatgagcctt tgtttttctg tcactttatt
    39001 atctcctttc acgcaaaaac gtttagtact atatagtacc tacaagtttt gataaatata
    39061 ttatacatca tttggaaaaa aaatcaatat atagactgta atatgaaatt tttgaaaaat
    39121 ttgttgttat ttttagtcgt ataaaaaaga aacttaagag tttcttaaga attgtttaaa
    39181 gaagttgcaa taaattagtg gtatgattat agtatgaaag agaatgtctt gaaatttttc
    39241 tgtatcaaat tccaattatg gaggtgtagt atatgaaaaa gaaaatttgt gtagcaataa
    39301 tttttgctct atttatagtt tttgtagaaa tgtttattga tagctctagc gaaggaagta
    39361 aaattatgac agctgaatta agtaaataca ggaaaggcgt aaatgtatta tcaataaaca
    39421 atattatagt agcgaataaa aaatatagtt tgcccaaaga ttattctcct caggaaagca
    39481 gtgaagcgag agatgctttt tataaaatga ataaagatgc tcaaaagtca ggattaaatt
    39541 taaaagcttt tagtacatat agaagttatg aatatcaaga tagattattt aagtcatatg
    39601 taaaagaaca tggagaaaaa gaagcaaata gattttcagc taaacctgga gagagtgagc
    39661 atcaaactgg acttgctttt gatattggag gagatgacca gtcttgttgg gcaaataaaa
    39721 agttcaacaa tacaaaagaa gctaagtggt tgtatgaaaa tgcatataaa tatggtttta
    39781 tacttagata tccagaaggt aaagagaata taacaggata tatgtatgaa tcttggcact
    39841 atagatatgt tggaactgaa catagcaaaa actttgcaat gaataatttg actttagaag
    39901 aatatttaca tataaattaa gagatggttt gttaaaatta ggttaaaata aaaaataacc
    39961 tagactatta gctgtgtaaa gtgatataat gtaaatacaa tttaagataa ctactcgaag
    40021 gggagtagct tacacgaaag tggtaattaa tcgtcaagac agtagaaata ctcggttaat
    40081 tagcaaggga ttccttgata gcaagacctt caaaataagc attaggtatg tttgttttgg
    40141 ggtctttttt tattcaagga atttttattt aaaaaaattt aaatttcaag tatacataag
    40201 agcccccaaa cataaaataa atttattgaa gaggagggca acaaatgtct tacaaaagta
    40261 cttatcaaga agtaattaaa aatttagact caagtttatc tggtttgagt aaagaaagag
    40321 cagaagagtt gttagaaaaa aatggagcta atgaattaaa agaagcagat aaggttccta
    40381 cttataagct tttcctagaa agttttaaag acccattagt aataattcta ttgatagctg
    40441 ctttagtaca aatattttta ggtgaaacag tggagtctat aataattttt gcagttatta
    40501 ttataaactc tgttctgggt gttgtacaaa caaaaaaagc agaaagttca ttagaaagtt
    40561 tgaaaaattt atctgcacca aacgcaaagg taataagaga caataaaaaa atgacaattc
    40621 cagcaaaaaa tctagtagtt ggagatattg tattcttaga agctggcgat tacataccag
    40681 cagatggaag gcttatagaa gcacaatctc tcaaggttgt agaagggatg ttaactggag
    40741 aatcagaacc agttttaaag catatagaaa aaataagtga agatgtaagt ttaggtgacc
    40801 agaaaaatat ggtatttagt ggtgctgtag ttgtttatgg tagaggttct tttgtagtga
    40861 ctggaacagg tatgaatact gagatgggta aaatagctgg gcttttagaa agtgctgaaa
    40921 ataaacttac accattgcaa caaaaaatag aggattttag taaaaaactt ggtgtaggta
    40981 ttgtaatact tgctctttta atatttataa ttcaagtagc aagaaattac tttatggctg
    41041 gaaatggaga aatgacacaa attattttag attcattcat gttctctgta gcagtagcag
    41101 tagcagctat accagaagct ctatcatcaa tagtcactat agtattggct gttggaacaa
    41161 atagtatggc aaaaaaacaa gccataataa gaaaattacc agcagtagaa actttaggtt
    41221 caacaagtgt aatatgtact gataaaacag gtactcttac acaaaataaa atgacagtag
    41281 ttgattatta tatgtatgga actaataatg atgagttaga taaagaaaaa gtaaactatt
    41341 cttatcatgc taaattattg actatggttt ctacattgtg taatgactct catataacta
    41401 gtgatggtaa agaagttggt gacccaacag aagtggcttt aataaattat tcaagtaaaa
    41461 atgatttaga ttatgataaa ttaagaagta agtatatcag aataaatgaa ataccatttg
    41521 actcagacag aaagcttatg tctactgtaa atagtatata tggagattat ataatgttta
    41581 caaaaggtgc tccagatatt gtgtttagta gatgtaaata tgctttgaaa aatggttcaa
    41641 aagtagatat aacagatgag ataatagaag aatataaaca taaaaatgaa gagttctcaa
    41701 atagagcact tagagtatta gcttttgcaa taaaagatgt cccagaagaa gattttatac
    41761 cttcaattga tgacgaacat gacatgacat tggttggaat aatggcaatg atagacccac
    41821 caagagaaga agtaatggat gcagtaaaag aggcaaagag tgctggtata aaaactgtta
    41881 tgataactgg tgaccataaa acaacagcag cagcaattgc aaaagagatt ggtataatgg
    41941 aagaaggaga cttggctctt actggaaaag agcttgatgc tttgagtgaa gaacaactat
    42001 atgaaaaact agaaaatata agtgtatatg ccagagtctc gccggaaaat aaaattcgta
    42061 tagtaaaagc atggcaacat aagaataata taacagcaat gactggtgat ggtgttaatg
    42121 atgcacctgc attaaaacaa gcagatatag gaatcggtat gggaagtggt actgatgtag
    42181 caaaagatgc ttctgctatg gtattggttg atgataactt tgcaagtata gtaaatgctg
    42241 ttgaagttgg tagaacagta tacagtaata taataaaatc aattacttat ctatttgcag
    42301 gaaacttagg agctatagta tccatagtat ttgcagtgtt tgcaggttgg tcaaatccat
    42361 ttacagcttt acaacttttg tttataaact tagtaaatga ctctttacca gcaattgcat
    42421 tagggtttga aaagtcagaa aaaaatataa tgaataaacc tcctagacac ccggatgaaa
    42481 gtatactagc aggaggaaca ttgaaggcag ttgctataag aggttgtata ataggtgtag
    42541 ttacaataat tgcacaatat ataggattac aagtatctcc agaacttgga gtagcaatgg
    42601 cattttcaac attgatatta gctagaataa tgcaaacatt acctgcacgt tctaataatc
    42661 aaacagtaat aaaattaggt tttttcagca ataaatacgt tataggagca gttttagtct
    42721 gtcttgggct ttactcttta acactaatac cagtgctaag aggaatattc tctataccaa
    42781 caacgtttgg attgtaccag ttggggattt gcctagggtt agcattaatt tcatcaatat
    42841 taatggaact taacaaatta ataaatagaa gtgaagtaaa ataatcaaaa aattaaaggg
    42901 catattgatt ttaacaatat gccttttata aatagtctaa tttattctat attatcgatt
    42961 atttggaatg cttttataac ttcaggtaat tctttttctt caggcattct aaatcttata
    43021 aaatttttat caagtccagt aaaatcactt ccagatataa ctcttatttt taatttagca
    43081 aactcttgtt gtaaatctat gtccttgttt ttatgttcaa ctgtcataat tgatacagta
    43141 tcactagttt cagctatatt aaggtttttc catggaatta ataattgatt ttttatatct
    43201 tttgtttttt cttttaattc ttctataaat tgaacatcat ctaataaatt tgctgcaata
    43261 ctacgagata tttcagacac ttcgtaagga gtagaaatct ttttaatagg gctaacaagt
    43321 tgttctggaa gaactgcata tcctgctctt agtcctgcta aaccaaatcc ttttgaaaat
    43381 gtttttaaag caattacatt atcataatta tttagaagct tgacagctga attttctttt
    43441 ggcatgtatt caccataagc ttcatctacc ataactgcta tatcatattt agctgcttcc
    43501 cttactatat tttcaattga tgataaaggt ataatttgtc ctgtaggatt gtttggattg
    43561 tctatgtaaa ttactttata ttctggattt attttttcaa taaattcttt ttcattaaac
    43621 ttgaaattat cctctttctt taaaagaaca taatcataag ttgcaccatg catttttata
    43681 tctgtctcat attctgagaa ctgaggtgaa tatcctaaaa ctttatctcc cttttcaata
    43741 aatagtctat ttaaaaggta aataacatgt atagaaccat ctgccaaaca aattctgtca
    43801 gtatctaatg ctataaaatc tttccaataa tcgactatat tatcttttaa agcaattgaa
    43861 tgaggatatc ctcttatcat atcaaatttt aaagcattaa aagcttctac agctttgttt
    43921 gagtaagaca cggtatttat accttcacca cagtctatct cgaatacatc ttctgaatgt
    43981 ccagattcta ttgcataact ttttttcaac tgcatttcaa tagctttgtt aatttttagt
    44041 ttcatacttt atcactcctt atttagtcaa taataaatgt tataaaagtt gctagattta
    44101 aaatattatg aaaatatata atagtaaaaa tgaatataaa tattata
//
LOCUS       DAYAKB010000028        43673 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.028, whole genome shotgun sequence.
ACCESSION   DAYAKB010000028 DAYAKB010000000
VERSION     DAYAKB010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.028"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            301..765
                     /locus_tag="ACGI3L_001824"
     CDS             301..765
                     /locus_tag="ACGI3L_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFG9197533.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            772..1266
                     /locus_tag="ACGI3L_001825"
     CDS             772..1266
                     /locus_tag="ACGI3L_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HFG9197534.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            1282..2307
                     /locus_tag="ACGI3L_001826"
     CDS             1282..2307
                     /locus_tag="ACGI3L_001826"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0046314 - phosphocreatine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HFG9197535.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            2294..4741
                     /locus_tag="ACGI3L_001827"
     CDS             2294..4741
                     /locus_tag="ACGI3L_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFG9197536.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNKVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            4921..6294
                     /gene="radA"
                     /locus_tag="ACGI3L_001828"
     CDS             4921..6294
                     /gene="radA"
                     /locus_tag="ACGI3L_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFG9197537.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSEKLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            6297..7367
                     /gene="disA"
                     /locus_tag="ACGI3L_001829"
     CDS             6297..7367
                     /gene="disA"
                     /locus_tag="ACGI3L_001829"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning diadenylate cyclase DisA"
                     /protein_id="HFG9197538.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            7456..8550
                     /locus_tag="ACGI3L_001830"
     CDS             7456..8550
                     /locus_tag="ACGI3L_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFG9197539.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            8679..10856
                     /locus_tag="ACGI3L_001831"
     CDS             8679..10856
                     /locus_tag="ACGI3L_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197540.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(11036..11887)
                     /locus_tag="ACGI3L_001832"
     CDS             complement(11036..11887)
                     /locus_tag="ACGI3L_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197541.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKNLPKI"
     gene            12104..13270
                     /locus_tag="ACGI3L_001833"
     CDS             12104..13270
                     /locus_tag="ACGI3L_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HFG9197542.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFAMIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLVKCVAQEWYPIEY"
     gene            13292..14938
                     /locus_tag="ACGI3L_001834"
     CDS             13292..14938
                     /locus_tag="ACGI3L_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFG9197543.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            15035..16408
                     /locus_tag="ACGI3L_001835"
     CDS             15035..16408
                     /locus_tag="ACGI3L_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9197544.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            16853..17806
                     /locus_tag="ACGI3L_001836"
     CDS             16853..17806
                     /locus_tag="ACGI3L_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HFG9197545.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            17844..18806
                     /locus_tag="ACGI3L_001837"
     CDS             17844..18806
                     /locus_tag="ACGI3L_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HFG9197546.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            18831..19817
                     /locus_tag="ACGI3L_001838"
     CDS             18831..19817
                     /locus_tag="ACGI3L_001838"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFG9197547.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            19830..20876
                     /locus_tag="ACGI3L_001839"
     CDS             19830..20876
                     /locus_tag="ACGI3L_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HFG9197548.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            21043..22773
                     /gene="lpdA"
                     /locus_tag="ACGI3L_001840"
     CDS             21043..22773
                     /gene="lpdA"
                     /locus_tag="ACGI3L_001840"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFG9197549.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            23191..26139
                     /locus_tag="ACGI3L_001841"
     CDS             23191..26139
                     /locus_tag="ACGI3L_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197550.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            26117..26581
                     /locus_tag="ACGI3L_001842"
     CDS             26117..26581
                     /locus_tag="ACGI3L_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9197551.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            26694..26996
                     /locus_tag="ACGI3L_001843"
     CDS             26694..26996
                     /locus_tag="ACGI3L_001843"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9197552.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            27073..28422
                     /locus_tag="ACGI3L_001844"
     CDS             27073..28422
                     /locus_tag="ACGI3L_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFG9197553.1"
                     /translation="MEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGLTVGVG
                     FIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALIIPIGL
                     VVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIVLVMAD
                     LTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQKKFGL
                     FGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLPVSEAA
                     QEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVLPFADL
                     AVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFKMPEGA
                     TMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKLSIEE"
     gene            28457..28930
                     /locus_tag="ACGI3L_001845"
     CDS             28457..28930
                     /locus_tag="ACGI3L_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197554.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            29102..29752
                     /locus_tag="ACGI3L_001846"
     CDS             29102..29752
                     /locus_tag="ACGI3L_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFG9197555.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            29926..30858
                     /locus_tag="ACGI3L_001847"
     CDS             29926..30858
                     /locus_tag="ACGI3L_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HFG9197556.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            31132..31845
                     /gene="ispD"
                     /locus_tag="ACGI3L_001848"
     CDS             31132..31845
                     /gene="ispD"
                     /locus_tag="ACGI3L_001848"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFG9197557.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            31842..32327
                     /gene="ispF"
                     /locus_tag="ACGI3L_001849"
     CDS             31842..32327
                     /gene="ispF"
                     /locus_tag="ACGI3L_001849"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HFG9197558.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    32422..32630
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            32694..34409
                     /locus_tag="ACGI3L_001850"
     CDS             32694..34409
                     /locus_tag="ACGI3L_001850"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFG9197559.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFNRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            34531..35976
                     /gene="proS"
                     /locus_tag="ACGI3L_001851"
     CDS             34531..35976
                     /gene="proS"
                     /locus_tag="ACGI3L_001851"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFG9197560.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            36414..37895
                     /gene="gltX"
                     /locus_tag="ACGI3L_001852"
     CDS             36414..37895
                     /gene="gltX"
                     /locus_tag="ACGI3L_001852"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFG9197561.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            38116..38271
                     /locus_tag="ACGI3L_001853"
     CDS             38116..38271
                     /locus_tag="ACGI3L_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197562.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            38416..39813
                     /gene="cysS"
                     /locus_tag="ACGI3L_001854"
     CDS             38416..39813
                     /gene="cysS"
                     /locus_tag="ACGI3L_001854"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFG9197563.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            39816..40211
                     /locus_tag="ACGI3L_001855"
     CDS             39816..40211
                     /locus_tag="ACGI3L_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III domain-containing protein"
                     /protein_id="HFG9197564.1"
                     /translation="MEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRKVNDLHK
                     LAIKYVKAKAQATIIHEVEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKHATGFEA
                     LVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            40317..41075
                     /gene="thyX"
                     /locus_tag="ACGI3L_001856"
     CDS             40317..41075
                     /gene="thyX"
                     /locus_tag="ACGI3L_001856"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HFG9197565.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            41088..41825
                     /gene="rlmB"
                     /locus_tag="ACGI3L_001857"
     CDS             41088..41825
                     /gene="rlmB"
                     /locus_tag="ACGI3L_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFG9197566.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            41828..42355
                     /locus_tag="ACGI3L_001858"
     CDS             41828..42355
                     /locus_tag="ACGI3L_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFG9197567.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            42420..43067
                     /gene="sigH"
                     /locus_tag="ACGI3L_001859"
     CDS             42420..43067
                     /gene="sigH"
                     /locus_tag="ACGI3L_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HFG9197568.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            43141..>43673
                     /locus_tag="ACGI3L_001860"
     CDS             43141..>43673
                     /locus_tag="ACGI3L_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFG9197569.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSAL"
BASE COUNT        17889 a         4542 c         8200 g        13042 t
ORIGIN      
        1 aataaaaaga aagtattttt ttattattat ttttacaaat gtttagtaat aaagatgaga
       61 aggtatattt aaaatataaa gtatttaaag ttctgaaatc taatcatgaa gcaaaaaatt
      121 agcatttggt tatcaataaa tataataaat aaaaactcat aattaatgaa agaataaatt
      181 catatctaaa tttctataaa aaatttaaat ttatacaatt tagggcttta aaaatttaaa
      241 taataggtgt aaaataatag tcaaagaaag tcaaaaataa aaaggtgtgt ggtgatatta
      301 atggcaacta tgacagatat aattgaaaaa tttattaaag atttgatgga agaagataat
      361 agcatacaaa ttcaaagaaa tgaactagca aacttgttta gttgtgcacc atcacaaata
      421 aattatgtct taacaacaag atttacaata gatagaggat attacattga aagtaaaaaa
      481 ggtggcggag gatatgttca aatagaaaaa atacgaaaaa gtaaagatgg gcatattaga
      541 gaactactaa atgaaaaaat aggaagtcag atatcctata aaaaagcaaa agaattatta
      601 gaaggtttaa aagagtcgga tttgattaac gaaagagaat taaaattaat attatatgca
      661 atagatgata aatcattgtg tatgccaata tatgaattaa aagagaaggt aaggtctaat
      721 attttaaaga atataataat aggattattt agtatagagg agtgataatt tatgctatgt
      781 caaaaatgca ataagaataa agcatctgta tattataata agatagtcaa tggagaaaaa
      841 acagagatgt atttatgtag tgagtgtgca aaagagaata cagaaatgaa ttttaactta
      901 gatatgcctt tttcaatgat ggatatattt tctaatttag gttttcaacc taaaaaagaa
      961 cttgaggaaa agctagtttg tcctaaatgc aatacaacat atagtgagtt taagaataat
     1021 gggagatttg gatgtagtga atgttataat gcatttagta gtcaagtaaa tccaatgctt
     1081 caaaatatac atgggcatat agaacataca ggaaaagcac ctaaaaaatc tttttataag
     1141 ataagtgtag aaaatgagat taaagaacta aaagaagatt tagatagagc tataaaaaat
     1201 gaagagtatg agttagcagc tcaatttaga gataaaatta aatatttaaa aggttctatt
     1261 gactaagatt ggagtgatat tatgaaagag aacatagtca tgaaatcaag agttaggcta
     1321 gctagaaatt taaataacta tccatttcca aataaattag ataaagaatg tgccatggaa
     1381 ataatagaaa aagtaaaaaa tgcgtttatt aattctaact tagaacaaaa agaagaattt
     1441 gatttctata aaattgaaga tttagaccaa tctaaaaaaa tgcttatggt tgaagaacat
     1501 ataataagcc cagatttagc agaaaatgat aaaagtgcag ttatagtaaa aaaagataaa
     1561 actataagta taatgataaa tgaagaagac catataagga tacaaactat atgtgatgat
     1621 ttaaacttag aatatgcata tagtgtagca aatgaaatag atgatttgtt agaatcaagt
     1681 ttagaatatg cctttaacac aaagctaggt tatctaacat cttgtccaac taatacagga
     1741 acaggaatga gagcttctgt aatgatgcat ttaccagcat taagtcaact aggctatatg
     1801 gatgaacttt ataaaatttc atcacaaata ggtatagcaa ttagagggat atatggagaa
     1861 cgaacagaag cgttgggaaa tatatatcaa atatctaatc aacttacact tggaagaaca
     1921 gagtctaata ttatagaaaa tgtaagtgga cttacaaaag atgcaatttc aaaagaaata
     1981 aaagctagag aaatattgca aaaaaaatta ggtataaaac tagaagataa aatatttaga
     2041 tcgataggga cacttgaaaa ttcaagagta atgagtagcg cagaggcaat gagccatcta
     2101 tcaaatataa aaatgggaat agaaatgaac tatatagata aactagattt aagggctata
     2161 gaacaactta tgataggtat acaaccagcg catcagtcaa taatgtataa gagtgatgat
     2221 gttgagaata gagatataaa tagagcaaca tatattagag aaactttgga aaaattaaga
     2281 ggagggatga attgtgaact tcaatagatt tacacaaaga gctaaaaagg caattgattt
     2341 agcgtttgaa tctgctaaaa gtctaggaca caatattgtc ggaagtgaac atatactttt
     2401 aggtctttta agagaagaag aaggtatagc tgctaaagtt ctaagtaaag ttggatttac
     2461 agaagcttat ttagaaggca aaatagttga tatggaaggt aagggagaag aaatctcaga
     2521 agatatagta ttaagtccaa ggagtaaaca aatacttgaa ttatcaggaa tgtttgcaaa
     2581 taaattaaaa acaaattata ttgggactga gcatatatta ttagcaatta ttcaagaagg
     2641 tgaaggaata gctaataaga ttttaaatta tgctggagta aatgatagga ctttagccca
     2701 attaacaatt gatatgatgg gtattagtga taaaaatcaa tacaaagcag agaatagtta
     2761 cacgggcaac cagaatcaag cagaatctaa agtacttgat aagtatggaa gaaatcttac
     2821 actatatgca aaacagaata aaatagaccc tgtaataggt agagaaaaag aaatacaaag
     2881 agtaatacaa atattaagta gaagaactaa aaacaatcca gtgttgatag gagacccagg
     2941 tgtagggaaa acagccatag ctgaaggtct ggctacaaat atagccttag gaaatgttcc
     3001 agaaacacta aaaaacaaaa ctttatactc tttagagatg ggttcattat tggctggagc
     3061 taagtataga ggagaatttg aagaaagaat taaagaagtt gtagatgaag ttgttaaaaa
     3121 tggaaacata atcttattta tagatgagat gcacacaata ataggggctg ggtctactgg
     3181 agaaggctct atagatgctt caaatatatt aaagccagcc ttagcaagag gagaaataca
     3241 agttataggt gcaactacaa ttgatgaata tagaaagcat gttgaaaaag attctgctct
     3301 agaaagaaga ttccaaccag ttatggtaga tgaaccaact aaagaggact caataaaaat
     3361 attagaagga ttaagagata aatatgaagc tcatcataaa gttaaaataa ctgatgatgc
     3421 tataaaggca gctgtagaat tatcaactag atatatatca gacagatatc tgccagataa
     3481 agctatagac ttgattgatg aagctgcatc aaaagtaaga ttaaaagaaa atacacctcc
     3541 ttcagaaata aaaaaattag aactagaaat agaaaatata gataaagaaa aagaagaagc
     3601 agtaagatgt caagactttg agaaagcagc caaaataaga gatgaacaag gtctacttaa
     3661 aaaacaatta gaagatgtta gagaaagatg gaacaagtca tctaaacatt cagatttagt
     3721 tgatggagaa gttattgctg aagtagtggg cttatggaca ggaataccag ttaataaaat
     3781 tcttgaagaa gaggctgata gacttttgag acttgaggaa atactgcaca ataaagttat
     3841 aggtcaagaa caagcagtaa aatctatttc aaaggcaatc agaaggtcaa gagcaggtct
     3901 taaagaccct aatagaccaa ttggttcatt tttattttta ggtccaacag gagtaggtaa
     3961 aacagaatta tctaaggcat tagcagaagt gcaatttgga gatgaaaatc aaataattag
     4021 aatagatatg tctgaatata tggaaaaaca tgctgtgtca agaatgatag gttcacctcc
     4081 aggttatgta ggtcatgatg aaggtggtca attaactgaa aaagtaagaa gaaatccata
     4141 ttcagttatc ttatttgatg agatagaaaa agctcatcca gatgtattta atattctgtt
     4201 acaaattcta gatgatggta gactaactga ttcaaaagga agaactgtag attttaagaa
     4261 tactattgta ataatgacat caaatgttgg agcatctaca attggtagac aaaaaacttt
     4321 aggatttagt atagctaaag gagacgaaga agaaaaatct caatatgaaa aaatgaaaga
     4381 aaatataatg ggtgaattaa aacaaagatt cagaccagag tttttaaaca gaatagatga
     4441 tataattgtt ttccactcac taaatgaaaa tcatatatca aaaatagtac ttttaatggc
     4501 agcgaaacta caagagagat taaaagaaat ggatataaaa ttagaaatga gtgatgaggc
     4561 tgttaaatta atttctaaat ctggatttga cttagaatat ggagcaagac ctcttaaaag
     4621 agctttacaa aaagagttgg aagatgagct atctgaagca atcttaaaag gtaatgtgaa
     4681 aaagggaagt aatgtagtag caaaagtcaa agatgaaaaa atagtttttg aaactaaata
     4741 atttaataga gttgcatttt aaaatattgc aaatataagt tttataatct aaacaaaatt
     4801 ttaagggcaa tgaatctata ataattcatt gtccttaatt attttattta atctttacat
     4861 attgtctttc agatatgcta aaattatagt atagaataaa aaattaagga tgataaaagt
     4921 atggcaaaaa taaaaacaaa atatgtatgt caatcttgcg gatatgaaac agctaaatgg
     4981 cttggtaaat gtccagaatg tacaaaatgg aatacatttg tagaagaaat agaccaaaaa
     5041 agcaccaaaa aagaggtctt tataatagat aaatcttcat ctaaaccagt cagtataaac
     5101 tcaatagaga gtaaagaaga agagcggttt acaacagata taaatgaatt agatagagtg
     5161 cttggaggag gtatagttaa aggctcttta gtgcttgttg gtggtgaccc tggtataggt
     5221 aaatcaacac ttttaatcca agtatctagt aatgttgcca atttaggaaa aactgtttta
     5281 tatataactg gagaagaatc agaatctcaa ataaaaatga gagctaaaag attaggtatt
     5341 aactcagaaa aattatatat atttgctgaa aataatttaa gtataattga atcttattta
     5401 gaaagtgtaa atccagaatt aataattcta gactcaattc aaactgtctt cagtccagaa
     5461 atatcctcgg caccaggaac tgtcagccaa attaaagaag gtacttcaaa attcatgaaa
     5521 atttctaaaa aaatgggaat ttcaacgttc atagttgggc atgttacaaa agaaggttca
     5581 ctagcaggac caaaattatt agagcatatg gttgatactg ttctatattt tgaaggagaa
     5641 agatataata cttatagatt agtaagagct gttaaaaatc gatttggttc aactaatgaa
     5701 cttggagtat ttgaaatgag ggatttagga ttagtagaac ttgataatcc atctaaaatt
     5761 ttaatctctg aaaaaccaaa agatgtagca ggttcagtaa taatatctac tgtagaaggt
     5821 acgaggccaa tgttacttga attgcaagca ttagtttctc ctacaagttt tggtatacca
     5881 aaaagaacat ctacaggagt cgattacaat agagtaggta tgttattagc agtattagaa
     5941 aaacgtgttg gtttgcaaat acaaaatcaa gatgtctata taaacatagt tggaggaata
     6001 aagataaatg aaccctcaat tgatttaggg atagccattt ctgtagcatc tagttttaga
     6061 aatataccga tagatgaaga tatagctgtt acaggagaag tgggacttac aggagaagtt
     6121 agagcagtaa gctttataga aaagagaata gctgagtgta aaaaacttgg atttaaaaag
     6181 atagtagttc ctagaagtaa ttatgatgtt gtaaaagaga ccaaaggcat agaaatatgg
     6241 ccagtagata acttaagaca agctataaat atagtacttg ggaggaatca ataaatatgg
     6301 agaattttct agataataaa aatatgctat atgcattaaa aatgatatct cctggaactc
     6361 cacttagatt aggtctaaac aatgtactaa gagctaagac tggtggatta attgtaattg
     6421 caacaaacga agatgtaatg aaaatagtag atggaggatt tgctataaat gcagaatatt
     6481 caccatcata tctatatgaa ttagctaaaa tggatggagc tatagtttta agtggtgatg
     6541 taaagaaaat attatttgct aatgcacaac ttatacctga ctattttata gaaacatcag
     6601 agacaggaac aagacataga acagcagaaa gagtagcaaa acaaactggt gctatagtca
     6661 taggaatttc acaaagaaga aatgttataa cagtttatag aggaaatgag aagtatgtag
     6721 tcgaagatat atctaagata tttactaagg caaatcaggc tatacaaact ctggaaaaat
     6781 ataagacagt attggaccaa gctgtaacaa atttaaatgc cttagagttt aatgatttgg
     6841 taactattta tgatgttgca ttagtcatgc aaaagatgga aatggtaatg agagttacaa
     6901 gtataattga aaaatatgtg atagaattgg gtgatgaagg aactttagta agtatgcaat
     6961 tagaagaatt aatgggtaca accagaatag accagaaatt aatattcaaa gattataata
     7021 aagaaaacac agaaataaaa gaacttatga aaaaggtcaa aaatttaaat tcagaagaac
     7081 taatagaatt ggtcaatatg gcaaaactat tagggtatag tggtttttca gaaagtatgg
     7141 atatgcctat aaaaacaaga ggttatagga ttcttagcaa aatacataga ctaccaacag
     7201 caataataga aaacttagta aattattttg aaaactttca acaaatttta gatgcatcta
     7261 ttgaagaatt agatgaggtt gaaggaatag gtgaaataag agcaacatat ataaaaaatg
     7321 gactcataaa aatgaaacaa ttagtcttat tagatagaca catatgatga attttaaatg
     7381 aattttacta cttttttctt gaatataata tacactttgg tctataatag ataagtataa
     7441 ctagggggtg aagcattgat aaggaaagta acaagaatat tgtttatttt acttggattt
     7501 acaataggta taacaaccta tttaacatta atgaaagatt ttgaaatatt aacatttgga
     7561 aaagaaacat atggttatat cgcagctgta gtagcaggta taataatagc cattttagga
     7621 tatcttatag agccatgggt tgtaaataaa gtaaaagaaa ttgctaaaat agtggataaa
     7681 gaattgtcaa aatatcctca gactgatata ttgttagggt ctatgggtct tatagtagga
     7741 tttgttattg cgtatttatt aagtggatta gtaaatagaa taccaatagt aggtggaata
     7801 ctatccttac tattatattt attcctagga tatcttggaa tgaaagttgc gcttaaaagt
     7861 aaaaatgatt tatttaatat tggaaaacta ggaagattag caaatcctat taaggataaa
     7921 gataaggata aagaaaataa aaaagaagta aaagccattc ctccaaaagt attagataca
     7981 agtgtaataa ttgatggaag aatagctgat atttgtaaga ctgggtttat agaaggaaaa
     8041 cttattattc ctgcttttgt tttggaggaa ctaagacata ttgcagattc ttcagatgat
     8101 ttaaaaagag taagaggtag aagaggtctg gatatattaa atataattca gaaagaatta
     8161 aatatagaag ttgaaataag tgagagagac tttgatgata tagcagaagt tgatagtaaa
     8221 ttattaaagc ttgctcaggt tttaaatgga aaagttgtta caaatgatta taacttaaat
     8281 aaagttgctc aattccaagg tgttgaagta ttaaatataa atgagttagc taatgctata
     8341 aaaccagttg ctataccagg tgaagatatg gttgttcaag tggttaaaga aggaaaagag
     8401 gctcaacaag gtgttgcata tctagatgat ggaactatga tagttgttga tggaggaaga
     8461 aaatatatga atgagactat aaaagtactc gttacttctg ttcttcaaac tcctgcaggt
     8521 agaatgatat ttgcaaaacc taaaaattaa tatgttcaaa gaaacctata atttgggctg
     8581 tttattttaa atagatggtc caaatttatt tatttataac gataatgttt aatgtattct
     8641 taaagatggg gatttaaatc agaaagcagg gagaatttat gagaaaaaag attatatctt
     8701 tcttagcaac atttatcata atattaacat cagcaagtca gtatagtttt gcagatgata
     8761 tatcaacacg tggaaaagta atatttatag atatgaatag aactagtatg agtaatatgt
     8821 taagaataaa atcattaaga gaagaactag acaatagagg gtatattggc ttgatgaata
     8881 taagaggcga taaaggaagt gatgatagaa ggtcatatgc tagtatgggt gctggtggta
     8941 gagctaatgt ggctaatgaa gaagatatta attttgaaag ctcgagtaag gatagaaata
     9001 tagtttttga atcagctaca ggaaaaagtg caaaaggtat aaataattta actataaata
     9061 agtctataaa tgaaaattta aactttggag agtatggttc tgtattaggg tcattaggac
     9121 aaagtttatc tgataatgga ttaaaagcat ctgtattggg taattcagat ataattgaaa
     9181 atggtcaact tataaaaaat agaaacttat gtctaactgc aatggatgaa tatggaagaa
     9241 tacctaatgg aaatgtagat actataaata aaaaagactt atctatgcct tatggaatat
     9301 caactgatta tgataaattg attgtagaga ctaaagaagc ttacaaaaat aatgatgtga
     9361 tttttgtgga gcttggagac acatatagat tagatttata taaaccaaat ttaaatgaaa
     9421 aaacatatga gagtatgaaa gataacatag aaaaaaatat agatatatat ttaaaaaata
     9481 tattttctat ggttgaagaa aatgacactg tctacatagc aagtgcattt ccaagtgatt
     9541 tagattataa aaataaaaga agactttcgc caataataaa attaaatgga gaagggaaag
     9601 gtatattatc atcttcaact actagaagag aaggtattgt aacaaattta gatgttgggg
     9661 ttgaaatatt agacaacttt aatataaaaa atcaaaatat ggttggaaga aaatatgaac
     9721 ttattaacag agatgataat aaagaatttt tgatggatga atatcaaaag atagtatcta
     9781 tttcaagcat aaggtctaca atactgaatg gttttgtaag tatagttttc ttgtcatgga
     9841 tagttgctat gattgcaatt ttatttagaa agcatatatc aaaaaattat aaagaaacaa
     9901 cattttttat attaaaggaa cttttaaaaa taggaatagt aatgccactg tcatttatga
     9961 taacaccaat aatgaatttc aaaacaccat tagcaatatc tttaggaata attataataa
    10021 cacttactat atatcttata agtaaagttt taataaagaa cgatttaaaa aacatgctgt
    10081 tttttactgg attaaccata gtaattatgg ttattgatgc tgggtttggc tcatatttaa
    10141 tgaaaagcaa tgttatgagt tatgattgta taattggagc tagatattat ggagtaggaa
    10201 atgagtatca aggtgtggca atcggtagtg caatatttac atttgcaatt ttacttacat
    10261 ataaaaatat accaaaatgg tctataatag ttttttcttt ggttatctta attacaagtg
    10321 catctccaat tatgggagca aatgttggaa gtgctatttc tgaatgtgtt gcatttttac
    10381 tatttatact attgatatat aatgtaaaga tagatttcaa aaaaatcgta ttattaggta
    10441 tagcagtagt atttgtatta ggagtttttg tagcaataga tatgattttg ggaagtaatt
    10501 cacatttagg catgtttgta aaagaaattt actttaatgg accaggagaa ataatacaaa
    10561 catttagtag aaagatagag atgaatttaa agctagctca aaccagtgca tgggtaaata
    10621 tactgttaac tggaataggt gtaattttag ttcttatgat taatcagatt agatacttta
    10681 agcaactgat ggatgagtat ccaattgtat ttaaaggatt tatagcatca atagcaggat
    10741 gtttagtaac tcttttagtg aatgactctg ggattgtgtc atcagctaca gcctttattt
    10801 atgtaattgt acctatgata acattaagta taaatcttac agcattaaaa gaataagtac
    10861 tgtatgaata atatgtaaat attaatacat taatttaact tctttattta caaaataaag
    10921 aagaaagttt ataaaaaata aattataata aaaaagagtt tatctcaaaa ttgattattc
    10981 taatcaaatt ttaagataaa ctctttttta ttataaagat aaataacata taacttcata
    11041 ttttaggtag attttttctt atatgtttag gagtgcattt aaatttttcc ttaaaaattc
    11101 tgtaaaataa ttttgtatta gtaaatccat gagcttctaa tatactgcat aaggtatcat
    11161 ttgtattaat taagtcttta taaatatgag aaatacgcac atcatttaaa tactctaagt
    11221 aagtttgtcc catatactgt ttaaattttc tacaaaaata ttctggttgt aagtgtgcta
    11281 ccttagcgat tttgttaata gaaataggca ttttgtaatt aatctttgta tattctaaaa
    11341 ctggttcaaa ttttgacaaa tcaagtactg tttttttcat atttttatta cctacagata
    11401 ttttaaagtt agtatataat tcaaataaaa gttcaaataa taagcttgta aagagcagat
    11461 tagctgcagg aggagaacta agtttaattt ctctcatgtt ttctaatata agtttaactt
    11521 tacttgaatt ttttttatag ttattgtcat tggcattaac cttaaagtca aaatagcaat
    11581 ttttaaaatc agggatatat ttgtttagaa aagacaatgg tacttgcaat aatatagagg
    11641 tattttgata aatacatcta gttgagtgaa taattccaga attaatgaac atacactcat
    11701 tagcttttaa attataagtg taaccctcca tgttaatttg taaatcacca gaagttatat
    11761 aaattatttc taatgagtta tgccaatgat ttgctacata actaccacta tcatcaaata
    11821 gtttgaaatt aacatctaaa ttatcaatag gttcaattat ttcatgtgaa aaattatttc
    11881 tgttcataat aatatcctcc ttataatttt aaattataaa tagtaaattt ataatgttca
    11941 atattaaaaa gataatatag attaataaat tagataataa acatacttaa gaaaacggat
    12001 aaaatcaaat ataataactg tatattaaaa taacttaaaa aaattatttt attataagtg
    12061 caaaatatac ctatttaaat aagataagag gggaggattt tatgtgtata taaaaggtgt
    12121 aaatttagga ggttggttag ttttagaaaa atggatgacc tcaagtttat ttgaaggcac
    12181 agaagctgaa gatgaatact atttaccaag acagctttca agagaggcat atgaatctag
    12241 aattaagact catcgtagtg aatacatcac agagagagat tttgcaatga ttaaatctat
    12301 gggatttaat tcagttcgta taccagtacc atactttatt tttggagatt gtgaaccatt
    12361 cataggatgt gttaaagaac ttgataaagc atttgcttgg gcagataagt atgggcttag
    12421 tatattgata gacttacata cagttccagg aagccaaaat ggatttgata atggaggaat
    12481 atcaggtata tgtagctggt cacaaaatcc agaatatgta gcgtttacat taaatgtatt
    12541 agaaagactt gcaaaacgtt atgggatgag gcatgaattg tatggaatcc aaattttaaa
    12601 tgagcctata acagaaagaa tgtggaacat aatgaatgtt ccaaatcggt ttaaggctgt
    12661 agataaggag atggcaaggg ggagtaaacc taattcatta gagtttttac gtgattttta
    12721 tataaaagca tataaggtaa tgcgtcctta tatgagggag gaaaacgtta tagtatttca
    12781 tgatgcattt gaattaaaag catggaaaga ctttatgaga gaggaagaat ttaaaaatgt
    12841 tgttctagat acacaccaat atttgatgtt agctgaagca gatggatgtg aacaaagtat
    12901 tgatagctat ctcaaatata ttagggaaaa ttatgctaaa gatattttac aaatgcaaaa
    12961 atattttcct gttatatgtg gggagtggag cttatttaat tcatatgctt gtggtataga
    13021 tacaaatgga ggtcaatcac ctctaaatgg gattgaatca aatatagata aattatcaaa
    13081 agacgataaa agagaattat ataggaagat agcaaaagca cagcttgatg catggagaaa
    13141 tggaagtggt cactactatt ggaattataa gttattacta gatacagtta atgaagaagg
    13201 ttggatagga tgggatagtt gggacctagt caaatgtgta gctcaagaat ggtatcctat
    13261 agaatattaa actaaaattg gaggaaaaga tatgattaaa aaccctatac ttccaggttt
    13321 taatccagat ccttgtattt gtagaaaggg agatgattat tatcttgtag tttcatcttt
    13381 tgaatggttt ccaggtatac ctgtttatca ctctaaagac ttaaaaaatt gggagttata
    13441 tactcatatt ttgacagatg aaacaaaaat agatttgaag aagcttcctt catctaaagg
    13501 aatttgggca ccctgtttga cttattgtga agaagaagat ttattttata tagtttatgg
    13561 aattatgaac tctatgaatg caagatattt tgatgttgat aattatttaa ttacatcaaa
    13621 agatataaag ggagagtgga gtgaaccagt atatctacac tcatcaggtt ttgatgcgtc
    13681 tatttttcat gatgatgatg gtaaaaagtg gattgcatca ttagactggg agacaagaga
    13741 aggatatgaa aaacctggtg ttatatgttt agtggaatac tgtacaaaaa agaaagaaat
    13801 agtaggatat ccaaagagaa tatggtcagg gggaactgat agaggttgta ttgaagcacc
    13861 acatataaca aagcgtggag attactatta tataatgtgt gcagaaggtg gaactggata
    13921 tggtcatagt gtaactatgg gaagggctaa aaatatatgg ggaccttatg aaaaagattc
    13981 aatgaatcca attgtaactt caattccagg cgatttttat gaaagacatg accctgacca
    14041 tctaaagcct aaatactata atccagaatc aaaacttcaa aaatctggtc atggaagcta
    14101 tatagaaaca acatcaggtg aagtatattt agttcatcta acatctagac catttgtacc
    14161 agagttaagg tgtactttag gtagagaaac agctattcaa aaaatgaaat ggacaaagga
    14221 taattggctt cgaatggaag atgaaagtaa tttggcaaaa gaatacgtat cagaaagtaa
    14281 actagaagaa catttagttt catctatacc aagttttgat gactttgatt caaatgaatt
    14341 aggtttacag tactatgctc ctaggatttc accattatca tttgcagatg ttaagtctag
    14401 accaggatat gtaaggatta gaggacaaga atcaagaaca tcattaaata aagtgagcat
    14461 attggcaaga aaattaactt cagtatatgc aagaataacc actaagatgg agttttaccc
    14521 agaggtacat cagcatagtg cgggtttgat aatgtattat gataatatga attatataaa
    14581 tttaagaaag tattatagtg aaacattggg tcaaagtgca ctatcaataa tacatcttga
    14641 aaatggagag aaaacggaat ttttaaatac taggatacca ataaaagata taccaatata
    14701 tcttcgtctg tatgtacaag gtcgtaagtc atattttgaa tggagttatg atgaaaaaaa
    14761 ctaccagaga ataggaaagg tatttgatac aactaagttt tcagatgagt actgtaaata
    14821 tggagaattt acaggtacgt ttataggatt aacttgtgca gatcgtgtaa agcataaaca
    14881 ctatgctgat tttgattttt ttgaatatat agtagatgaa tcaaaagatg tcgattaata
    14941 aaatcattac taaaattttc agagcaaagg taaatcttat gctctgaaat aagaaacatt
    15001 agaaggcaaa tcttacaaaa aggagtatgg tattatgaat acagaagtta atgttaaagc
    15061 aactacgatt agatatgaaa agatttcatt ttttgaaaga atttcttatg gttgtgggga
    15121 tttggggtgc aatatcatat actcagctat gtcagcattt ttgctgtttt attatactaa
    15181 ttatgcagat gttagtgcag cagctgtagg tagtattatg cttgtatcta ggatactgga
    15241 tgggtttagt gacttaacaa tgggaattat agtggataga actaaatcca aatacggtaa
    15301 ggctaggcct tggattttga gaatggcgat tccttttgct atagcagcag tattattatt
    15361 ttctgttcca tcaaatcttg gtatcacttc taaattaatt tatattttta ttacatataa
    15421 cttagtttct actgttattt atacagcaat caatgtaccc tatgcaactc taaattcact
    15481 tataactcaa aaccagtatg aaagaggagt attaagtata tttagaatga tattagccac
    15541 ttgtggtacc ttactaataa atggacttac actacctcta gttgaatact ttggaaataa
    15601 tttatcagca tggactaaaa cattctttgt atttggaata gcatctataa tggtattttt
    15661 tataacattt actggaacca aggaaagagt aaaagcagtt aagcaagata ggaatgaagt
    15721 aataccattt aaaataggta ttaaatcttt atttagaaat aagtactgga tacaaataac
    15781 attatgttta gtttgcatat ttattgtatt tgcgataaat ggtggttcat ccgtatatta
    15841 tgcaaagttt attttgggag atgaaaaatt atttggtcct ataaatatgg tttcaaatat
    15901 atcccaaatt atagctatgt ttatggttgc tccttttata aaaaaatttg gaaaaagaaa
    15961 tgtattaata gtaggttcaa taatattaat atcgtcaaat gttatgttta taatagttgg
    16021 acaaaatcat ataggagtaa tatttgcaag tgctataaag ggaataggaa gtgctggaat
    16081 agcatcaaca atgtttgcta ttgtttcaga tactattgaa tatggagaat ggaagactgg
    16141 atatagaact gaggggctta taaatagtgc atctagtttt gggtttaaag tgggaaatgg
    16201 attaggttca gcaatattag gtgcagtatt atcaattggt ggttatgtag gaacatcagc
    16261 tactcaaagt gatttagcta tagtatcaat aaaagtatgt tttatatacc tacctatatt
    16321 tataacaata ttacaaatta tcataatgtc tttttataag cttgataaag aatatagtac
    16381 tatacttaat gaattaaata ctaaataatg aaaaagtttc ttataaagtc ttaagtttaa
    16441 ttaaggtcta ttgtaaatgt tccctataaa aactattata tatttatgat tattgaagaa
    16501 tttttagaga agcgaataat aaaaatataa gaagacttta aatgatgaaa tggttggttt
    16561 tttagaagtg atttaataag ttattgttat ttaaagcatt ataagtggac aattaatttt
    16621 taatttatgg agatgatatt taacaattag aagtaatata taatatgcac taagaagcaa
    16681 tttttcaact atttatgaag gtggtggtac aagaaaagta tcaccttttt tttgttatac
    16741 aaaaaaacag ttgacttttt atatgaaccc cttctataat gttactgaaa ttaagtaaaa
    16801 tgattgaaca aatgtaaaga taattgaaaa gcttgatttt ggaggaaagc aaatgaaaaa
    16861 aattggagac ttaagattaa tgatgaagtg ttgttcactt tattacgaag ataatttgaa
    16921 tcaacaggaa atagcaaatc aattgggaat atcaagacca acaatatcaa gaatattaaa
    16981 agaagctttt gaacaaggaa tagtaaaaat acagatagtt gatgttttga aaaatgatta
    17041 ccaaaaaata gagagaagtt tggagagaaa atataaatta aaagaagtaa tagtagtaga
    17101 tgataaacag gatgcactaa cacaaaaaca agaactagca agagctgtat ctgaatattt
    17161 aactagagta gtaaaggaaa atgatataat aggtgtttca ataggaacaa cactaaaaga
    17221 aataccaaga tatgtggaaa aaagtaactg taaaaatgtt acatttatac ctctattagg
    17281 agggattgga gacaatgaaa tagatattca tgcaaatcaa atagccgtaa gtttagcgag
    17341 ggcttttgga ggtgatttta aattattaca tgctccagct gttatgtctg acttgtctac
    17401 aaaagagaaa ctttgcaaag acgaaaaaat taaagaagta ctagatttaa tagataaaac
    17461 aactatagca attgtgggta taggaaatcc tatgagttta aactcaacaa taatggcttc
    17521 tggatacatg aatgaagcag atatagaaga tttaaaaaaa tacaactcaa taggtgcaat
    17581 ttgtttacaa gcctttgata aagaaggaaa aacttctata cttgaattta atcaaagagt
    17641 attaggagtg aaactggaag atttaaaaaa gataaaaaga acaataggtg tcgcttcagg
    17701 agatgaaaaa atagaggcaa taaaggcatc attaaaagcg aaatttataa atagtttagc
    17761 aattaatcac agtttagcac ttaaattatt agaagattgt gactaataga aagatagata
    17821 aaagttaaca ggagggaatg tatatgtcaa tatcaaaaga aacattgctt gaaatgtata
    17881 agagaatgaa tcaggctaga aaatttgaag agaaagttag ttggtttttt gcaagaggta
    17941 tggttcatgg aacaactcac ttatctgtag gtcaagaagc gtcaagtgtg gcggctgtaa
    18001 tggctttaga aaaaggagat ttagtatcat taactcatag aggacatagt caatttatag
    18061 gaatgggaat agacctaaat aaaatgatgg ctgaacttat gggtaaagaa actggatttt
    18121 gtaagggaaa aggaggctca atgcatatag cagatattga gtcaggtaac ttaggagcaa
    18181 atggagttgt aggtggaggt cttacaatag ctccaggagc tgcacttaca caacagtata
    18241 aaaaaacagg caaaatagtt ttatgtagtt ttggtgatgg agcatcaaat gaaggtactt
    18301 ttcatgaagg aataaattta tcttcaatat ggaaattgcc aataatattt tactgtgaga
    18361 ataatttata cggtatgtca acaagcataa aacgtcatat gaatatagaa agtattgcca
    18421 ctagagcagc ttcttatgga atagaaggaa tatcaataga tggatataac ccaatagaag
    18481 tatacgaaac agtacaaaaa gctgctgaga agtgtagaag aggagaagga cctgtattaa
    18541 ttgaaagtag aacttataga tggttaggtc attcaaaatc agatgcaaat gtatatagaa
    18601 caaaagaaga aatagaatca tggaaagcaa aagaccctat tgaattttta aaaaattatc
    18661 ttatagaaaa taatctatct aatgaagatg aattagataa gattcaagaa tttgcaaagc
    18721 aatcaataga agatgcagta gagtttgctc aaaatagccc aaatccaaaa atagagtctt
    18781 tattagagga tgtatatgca gactaagaat ggtaaaggag gaaaataaaa atgagtacaa
    18841 gggaattaac atatgcacaa gcaataaagg aagcaatgtc agaagaaatg agaagagatg
    18901 aaaatgtaat atttatggga gaagatatag gaatatatgg aggagcattt ggtgtatcag
    18961 ttggtatgat agatgaattt ggaccagaaa gagtaaggga tactcctata tcagaagcag
    19021 ctatagcagg agcggcagca ggtgcagcag caactggctt aagacctatt atggaagtaa
    19081 tgtttatgga ctttgtaaca atttctatgg atgcaattgt aaatcaagcg gcaaaaatga
    19141 gatatatgtt tggaggaaaa gcacaagttc caatggttgt tagatgccca ggaggttctg
    19201 gaactggttc agcagagcaa cattcacaaa gtttagaagc ttggttttgt catgtaccag
    19261 gagtaaaagt agttgcacct tctacaccag cagatgctaa gggattgttg aaagcagcta
    19321 taagagataa taatccagtc atatttgttg agaataaatt gttatacaga aaaaaaggtt
    19381 ttgtgccaga agatgactat gtaattgaaa ttggaaaggc agatattaaa agagagggta
    19441 ctgatgttac agtaattact tatggaagaa tgttacaaag tgttgaagaa gcagcagaga
    19501 ctctatcaaa agaaaatata aatgttgaaa ttatagattt aagaacttta tatccattag
    19561 ataaagagac tatagtaaag agtgtatgta aaactgggag agttttaatt tgccatgaag
    19621 cagctaagac tggtgggcta ggtggagaaa tatcagcact gataacagaa agtgaatcat
    19681 ttgattattt agatgctcca gtaaaaagaa tttgtggaaa agatgtgcca ataccatata
    19741 atccagagtt agaaaaagca gttgtcccaa gagttgatga aatagaagaa gcaataaaat
    19801 ctttaattgt tagataagga gggatagata tggtggcaaa taaaataaaa gccacaccag
    19861 cagctagaag tcaggcaaga aaagacaata taaaattaga taggctgatt ggaagtggag
    19921 aaaatggaag gattcattta gtagatgtgt taaattattt aaaagataat aaagcaaata
    19981 ctactccttt agctagaaga atagcagaag atttaaatat agatttagaa actattgtag
    20041 gtactggata taatggaaag ataagaaagt gtgatgtgga aaaattaact gcaaaagaaa
    20101 ctattgtatc gactaataca tctaaatcta gtgagaaaaa agagctgaaa attgaaaatg
    20161 aaaattcaag catgtttaac acagtagaag gaatatttga aaagccaaat ccaatgagag
    20221 ctactgtagc aaaacgaatg tcagaaagtt attttagtgc tcctgtattt acattcaata
    20281 tagaagtaga tgctacagaa ttgaaggtac ttagagcaaa gttaatcgac acagtaaaag
    20341 aatcaactgg agtaaaatta actatgacag atttaatagt aatggcagta tctaaaatac
    20401 ttccaaatca tcaagcctta aattcagcat ggacagatga gggtatattt agatataaag
    20461 atgtaaatat agctattgca gttggtttag atgaaggctt atatgttccg gtagtaaaaa
    20521 atgcaaacaa aaagtcttta aaagaaatag caaaagaaag caaagaactt gcggaaaaag
    20581 taaagacagg gaaacttatg ccagcagacc aagaaggtaa tacatttaca ataagtaatg
    20641 ttggaatgta tggtataact acatttacac ctataataaa tatgccttca agtgcaatct
    20701 taggggtagg tgctacacaa gataagtttg ttccagtaaa tggagaggct aaaataaaac
    20761 ctataatgaa cttatcatta acatcagacc atagagtaat agatggaaca gtagctgcaa
    20821 aattcttaaa agatttaaaa gaattgttag aaaatccttt atcaatgctt gtataggttt
    20881 tgatattttg ttactgatat aaatagtttg aatagattat attattataa ttgtttcagt
    20941 aaatttaaag cttttatata ttaagaatta tttttaacag taactatatg tgaatatgat
    21001 ttgcttaatt aaaatataag aaaataaata ggaggagagc ctatgtcagt agaagtaata
    21061 atgccaaaag caggagtagc catggaagaa ggtactatag tatcttggct aaagcaagaa
    21121 ggcgaagaag taaagattgg agaacctata ctagaaataa caacagataa agttaatatg
    21181 gagatagagt cagaaggaga aggtacactt gctgtaatca tacataaaga ggaaggtgaa
    21241 gtattaccag tatttacagt aataggtgta atagcagaaa aaggggaaaa tcaagaggaa
    21301 gtaaaagcta aatatttatc tggaaatgtt tcaaaagaag atatagttga agagaatcaa
    21361 aatatagaat ttaaagaaga aaaaataaac aaaaaagagt gtaatcatga ttatgatgta
    21421 gtggtaatag gaggaggacc tgggggatat ttatcagcat taaaagcagc tcttttaggt
    21481 ggaagagttg ctttagttga agaaaatata ctaggaggta cttgcttaaa tagaggttgt
    21541 atccctacaa agacttatat aaaaacagca gaaatattag aagaaattga ccaattatca
    21601 aagagaggtg taaaagtaac tgtagataaa gaacaggaca ttaagaaggc cataaaatat
    21661 aaaaatagag tagttaaaaa acttacagct ggtgttggcg gattattaaa aagtagagat
    21721 gtagatgtgt ttaatcttaa agctagtgtt aaagaagagc ataaagtaat tttatcagat
    21781 ggaaaagttt tagatacaga aaatataata attgctacag gttccaaagt aaggatatta
    21841 cctataaaag gaatagaatc aaatttaata ataactagta cagaagcatt agatttggaa
    21901 acagtgccag aagaattagt aataattggt ggtggagtga ttggttgtga atttgcagag
    21961 atattcaatt caagaggttc taaagtaact atagtagaaa tggaagatag agtaatccca
    22021 agaatggata aagagttaag cgaatcttta aaatattctc ttagtaaaaa aggtataaat
    22081 gtattaacta aaaagaaagt ttctgaattt aaagaagaag gaaataacat attagtgtgc
    22141 attgaaggtg aagagccaat aaaagcagat ttatgtctat atgctatagg aagagaagct
    22201 aatctttctg gcatagagga cttagatatt aaaatagata aaggttcaat agttgtaaat
    22261 agtaaaatgg aaacaagtat accaagcata tatgcagtag gtgatgttac tggaggtgta
    22321 atgttagctc atgctgcttt taaaatggga gaggtagcag cttcaaatgc tctaggtgtg
    22381 aataaagaag ttgacttagg tgcattacct agttgtgttt atacaattcc agaagtagca
    22441 tcagttggta ttacagaaga ggatgctaga aaaaaatata atgtaaaagt tggtaagttt
    22501 aattttgctg gaaatggaag agctttagct tctggtcaag aacaaggata tgtgaaggta
    22561 gtagcagatg ctaaatatgg agaaatttta ggtatacata tgtttggatg tggtgtagca
    22621 gaacttataa atcatgcagc atcatttaaa gcattagaga tacctactga tgaagcaagt
    22681 gagttgatat ttggtcatcc atgtacttca gaagctttaa tggaagcttt ggcagatgta
    22741 aatggagaat gtttacactt acctaaaaaa taaatctaaa cataaattat taatttaagt
    22801 ctattattaa tattaattta tatcataaaa ttttaaaaca cttacttagc catacccctt
    22861 attatgcaaa taatttattt gcataataag gggtattttt tatggaaaaa tatagaatat
    22921 agaatccttg tagtttttgt tgtacaaaaa agatagtaat ataaaataac attatcattt
    22981 tagaatgatt tcaattgtaa ttaggaaaag tgattttttt gtttttaaaa aaagtattat
    23041 ttgtaaaata taaaaaaaaa tttcttaata tttaaataaa agaatagctt aatttaaatg
    23101 ttattacttt ataaaaaaat aataagtaca aaaaaaacaa tatatggcat ataagttgct
    23161 atataaataa taaggaggga acaattataa atgaggcaaa gaataaaaaa cttaattgaa
    23221 aatgaagata agaaaaatcc tttaacagat gaagcgattt caagtaggtt aaatattcga
    23281 agagaagatg ttaccttttt gagaaatgag ttaaaaatag aagattcaag acaaagaaga
    23341 aaagttgttt taattaaagc tataaaagat attttaaaag aagaaaaaac tataaataaa
    23401 aatgatataa caagaagatt aaacagcatt gggtttacag tatcaagatt tacagtcata
    23461 caatacttaa aagagattca agattctggt gacctaaaac ttgataaaga gagtgatgat
    23521 aaaaaagaag aaataatcaa taatagagaa aataaagata tagcatttga taaactcata
    23581 ggtagtagtg gtagcttaag tacaattata aaactagcca aagcagcaat tctttatcca
    23641 cctcatggtc ttcatactat tattatgggg ccaactggtg ttggaaagag tgagttagca
    23701 gagtgtatgt ataaatttgc agtagaatca tccagattcc ctaagaatgc accatttata
    23761 gtttttaatg cagcagatta ttcagagaat ccacagcttt tgctatcaca gttatttgga
    23821 cacgttaaag gtgcttttac aggagctgat gagaacaaag aaggattagt atcaaaggca
    23881 gatggaggaa tattgtttat agatgaaata catagattac ctcatgaagg tcaagaaata
    23941 ctatttcaac tgattgataa aggtatggtc agaaagttag gagaaacaag actaacacat
    24001 aaaatagatg taatgattat ttcagcaact tctgagccaa tagattctca tttacttaat
    24061 acatttaaaa gacgtatacc tgtaacaatt gaaataccag aattagttgc aagaccatta
    24121 aatgagaggt ttgacattat aaataatttc ttcttaatag aagctcaaag aatgggagca
    24181 aacatacata taaagtcaga tgtattaaaa gctcttatgc tttacgattg tataggtaat
    24241 gtaggtcaac ttagaagtga tattcaagta gcttgtgcta ggggactatt aaaccaactt
    24301 acaaacaaac taaaagaagt aaatataagc atatcagatg tacctggata tgtaaaacaa
    24361 ggtcttataa aaatcagaaa ttgtagagga aaaatagaaa attatgtaga tggggattta
    24421 attatagact caaatcttca aggtgagata gaaaagaaaa atgaagatat atatactttt
    24481 ccagatgaaa tatacaaact tactgaaaga agacatattg atttattgga acaaggttta
    24541 gattttgatg ttataaatag aatcattgga ggagaattag aaagttgcat tcaaaaatac
    24601 ataaaacaag ttaaaaaagt ttctattagt aacaatcttc cagatataag tccaattgtt
    24661 ggaaaatata tcgtagagct aacttatgaa gtaatcaaaa tagcatcaca atacctaagt
    24721 tcactagaac cgaatctaca tttatgttta gcagttcacc taaaagcagc ttttgagaga
    24781 ttaaaagaag gaaaagtaat atcaaatgct catttgaaag aaataatagg aaattatcca
    24841 ctagaatatt ctgtagcaga aaaggtagct caatatttaa aggaaagata taacataaac
    24901 ttaccaaaag aagaaatagg tataatagca atatatttta aaatgagtag tagaagagat
    24961 atgtctgaac aaaaaaagat aggtgtactt cttatggctc acggaagagt agcatcttct
    25021 gtatgtgagg ttacaaataa actattagga attaatcacg caaggtattt agatatgcca
    25081 tttgagaaga aaccggaaga aatgattgaa gaagctacta caataataaa agatattgat
    25141 gaaggtagag gtgtgattat attagtagat atgggttcac tttcatattt tggagatatt
    25201 atttctggaa agactggaat taatataagg acaatatcta gatttgatac attgctttct
    25261 atagaggtta tacgaagagc agttttacca gatttaacaa tagacgagat agttgatgaa
    25321 gttaaaggta tagagccaca agtaaaagaa aaggttagta aatgtaataa tacaaaagta
    25381 gattttagaa aacctataat tttaacatta tgtattactg gattaggggg agcttgtaag
    25441 ataaaaaaaa tcctagagga aaatattaaa agtataactg aaaaggttga tatagaacct
    25501 ataggtatga ttgaatatcc aagtcttgat ttagagataa aacaaataag caatgataaa
    25561 aatgtaatcg ccatagttgg aacaattgac cctcagatag caaatatccc tttttttagt
    25621 ctagtagaca taaatgataa agcaaagtta aatcaaataa ataacctaat tgatacaaat
    25681 caaattggtg aaacaaataa aaaatatgaa ttatcagatt taatacataa agaagatata
    25741 tttgtggatt tacaggttaa atcaaaagaa gaagttctaa aatatatgag taaaaaactt
    25801 agagagaaag gttatgtgac aaaaaatttc tataaaaaag tagtggaaag agataactta
    25861 tttccaactg aattatcaga tgaaatagca atacctcaca cagatggaat agatgtaatt
    25921 aggccagcta taagtatagc catcttaaag aagcctattg tgtggagtaa aagtaaagta
    25981 aaaataatac ttttattagc tgtagaccaa aagtgtttta atccattaag cactctactc
    26041 tcatttatag aaacagatga atttaagaag ataaaaaaca ttaaagatag agattttatt
    26101 agggagatga tattagatgg agtcaatgaa aataattagt agcaatttaa tttttaaaaa
    26161 tattgaagtg tctaacaatg aagatgcatt aaagtttttg ggacaacgtt tgtttgacga
    26221 acagtatgta aaagaaagct acatacaagc tgttgtagca agagaaaaaa agtatgctac
    26281 agggttacca acagaaatat acggagtggc aataccacat acagatatag tacatgtaaa
    26341 tgagccagga atagcaattg gaatactgaa taaacctgta aaatttataa tgatgggtac
    26401 agacgatact gaaattgatg taaaagttgt atttatgtta gcagtgaaag agccacaaga
    26461 acaattgcaa ctattagaaa aacttatgac tatatttcaa gataagaata tactaaataa
    26521 tattgttgac ttaagtgaag aaagtgtgag tgatttatta aactctaaat tgaaaaatta
    26581 aacatgtaaa gtatattaaa aatgtaaaat taaacatgca aagtatgtta aaaaatataa
    26641 aaagattatt aaagatttct aactatagat atctttaaaa taaaataatt tcaatggggg
    26701 tgactaatgt ggctaaaaag atattagttg catgtggaac aggagtatgt acttcaacaa
    26761 ttgctataaa caaattaaag aaagcacttc aagacattgg taaattggat atggttaata
    26821 ttacacaatg taaagtagta gaagttgcat caaaagcacc tgattatgat ttaataattt
    26881 gtactacaca agtatctagt agtataaaaa caccagtgat aaatggatta ccttttttaa
    26941 ctggtgtcgg aatggataaa ttaatcaatg atgtattaga agagttagaa ttataattaa
    27001 aaaaattaag gaacatggtc tctaaaatca taagttttag agacttaaaa ttaaataatg
    27061 gagggtcttt atatggagat attaaatttc attgttggtc taggtgcaca agtaatgatg
    27121 ccaataataa tatgtatttt tggtttgata ttaggtacaa aactaggaaa atctttaaga
    27181 gctggtttaa ctgtgggagt tgggtttata ggtcttaaca ctattatagc tttgctaaca
    27241 gataatttag gtccagctac acaacaaatg gttaagaatt tagggctaag tttatcaata
    27301 atagatgtag gatggccagc agcatcagct atagcttttg catcaacagt aggggcttta
    27361 attattccaa taggtcttgt ggtaaatata gttatgctaa ttaccaatac tactcaaact
    27421 gttgatgtag acatatggga ttactggcat tttgctttta caggagcttt agtggcaggg
    27481 gctactcaaa gtgtaatgtg gggagtattt gcagcagtag caaatatggt aattgtattg
    27541 gtaatggcag atttaactgc tccaggtata gaggaatatt taggtatgcc aggtatatct
    27601 cttcctcatg gatttacaca ggcatttgtt ccaattgcta tagtagtaaa taaattatta
    27661 gacttaatac caggcataaa taagattgag ataaatgctg atacattgca gaaaaaattt
    27721 ggattatttg gagaaccttt aataatgggg tctgtaatag gtgtaataat tggtattgct
    27781 gcgaaatatg atataaaagg aatattacaa ttaggtgtaa ctatgggagc tgtattaata
    27841 ttaattccaa agatggcagc attattaatg gaaggattat taccagtatc agaagctgca
    27901 caggaattta ttgagaagag atttaaaaac agaggcaaga tttatatagg cttagattca
    27961 gcagtaggaa taggtcatcc tgttacatta tcagttgcac tagtgttggt tcctttgact
    28021 atacttatag cagctatatt gccaggaaat aaagttttac catttgcaga tttagcagta
    28081 attccatttg cacttgtatt aatcgtacca attacaaagg gaaatgtgtt tagaacatta
    28141 ataataggaa taattataat tacttctgga ttattaatcg caactaactt agctccatta
    28201 tttacccaaa tggctttaaa tgctagtttt aaaatgcctg aaggagcaac tatgatttca
    28261 agtatttgtg atggtgcgaa tccattaagt tgggtatttg taaaagttat gaactataaa
    28321 gttattggag gagtagtttt tggagttata gctttaggaa tggctattta caataggaat
    28381 agaataataa atgaaaataa aaagctatct atagaagaat aaggttaaaa caattttatt
    28441 aaggagtgta taggttatga aaaaatataa atatgattct aaaagatact tactcagtgt
    28501 tacaatacca ggatttttta tgattttaat attgatttat gcactgttta ataactatac
    28561 aaattttaat ttgaatatat atagtttgtt aataattgtc tgtacttatg gtatattcaa
    28621 tacttttata tcatcaagta atcctaaaaa aattattatt gatagcaaat gtatacattt
    28681 tacctcattt atgactacac ataagtatga aattaaagat atagaaaaga taagaataag
    28741 agaattttat aataaaaaaa tttatctaaa aattaatgat ggaaaacttt tcaaaggtag
    28801 gtattggata agaacaaata tgtttaataa tagtatagca ttatatagct atttcattga
    28861 gttggaagag tgcttatatc cagattcact aaaatttaga aataaaaaat ttgagaataa
    28921 gaacatataa aaataaaaaa ttgaattgaa gcctagctta atcttttttg ataagatata
    28981 agtttgaact ttatactaaa tttttagaat tttcaatcaa gacaataaca taatagctaa
    29041 gcaattagaa cacaactaag atgtataagg catgtatatg atgaatggga ggatttaatt
    29101 aatgttatta gagaaattaa gaaaagaagt attacaagca tctttagacc ttttaaacta
    29161 taatttagtg acattaacag gaggaaatgt aagtgggaga gatgaacaaa ctggctatat
    29221 agcaatcacc ccaagtggaa tggattatag aaatcttaca ccaagtgata ttgttatagt
    29281 agatgtagat ggaaatatta tagatggaaa atggaaagca tcagtggatt tatcagacca
    29341 cttgtatata tataagcata gagaagacat aaatagtata attcatacac attctacata
    29401 ctcaagttgt tttgctattt taaatgaacc tatagaatgt gcaagtacaa ctcttgcaaa
    29461 tgaagtaggg ggttcagtac cagttgcaaa attttcgcca ccaacatcta aaaagatggg
    29521 aaaatgtgtt attgaagcaa ttggtgacaa aagagcatgt cttttagcaa atcatggcgt
    29581 aattgcagtt ggtccatctg taggacatgc tcttacagcc gctgtaatgt tagaagattc
    29641 agcaaaagta tattacttag caaaatcaat tggcacacca gtgctactgc ctgatgaaga
    29701 aattcaaaga gcgagagatg tattttttaa tgtctatggt caggataaat aaattagata
    29761 aaattttaaa agtaatatga aaatatagat attcaatgat attaaggaga tttataatga
    29821 tataataagt ttaatagtta agaagtaaaa tatgaaatgt aatagtatat aaattcattt
    29881 aagactaaaa agaataagat aaaataaaaa ggagtctgta tttctatgta ttacttatta
    29941 aacaaaagca caaatcctta ctttaatttg gcattagaag aatatctatt tttaaatgat
    30001 aaatataatg atgatattat aatcatatgg agaaatgaag aatccatttt tataggtaaa
    30061 aatcaaaatc catatcagga agtatatcat gatgttattg aaaagggaga aattcctatt
    30121 ttaagaagaa tatctggagg aggaactgtt tatcatgact taggtaatat caatatgtca
    30181 ttcatacaaa aagataggca acttcatgag atagattttt tggagcatac taagtttatg
    30241 caaaagatgc tttcaacctt aggactagat gtatctataa ctgaaagaaa agatttattt
    30301 ttaaatggga aaaaaatttc aggctctgca cagtctataa aaagaaaaaa ttctctttat
    30361 catggaactc ttctttacga ttcagattta aataaattaa ctaaatattt aaattcaaat
    30421 aaagcaactg aatcaaatgc aactaaatct gtttcaagta aagttacaaa tattaagttt
    30481 ttactcgaaa aagatataaa ttacttttta gattattgtg ttgaatattt aaaatctaat
    30541 ataaagaata taaaagaact tgaattggat gaagaagata ttaaaagtgt atacaatata
    30601 ggagaagata aatataaaaa gatagagtgg acatatggta aaacgccgaa atttcaagta
    30661 gtgctaccat ttaataatga aagtaaaata aatatacatg ttaacagatg gaaagtatca
    30721 aaatttttta tttcttatga tgataatgta attaatatgg acaagttgtt agatttgaat
    30781 ttctttaaag aagaaataaa agagagtatt ttagaaaatt atccacatta catagattta
    30841 atcaatttaa tattttaata taaaacctct aatttgataa aattgtctta tatcaaacta
    30901 gaggttttta atattcttgc atattaacaa ccattacaaa attgtaaaat taaaaacaac
    30961 actattgaaa aatcaatata tattgtaata aatatatgtg tttttcatta gcaaatagac
    31021 attaactatt tatacaactg aaaatttaat atataattaa tcagatggtt aaaataaaaa
    31081 tattaaaagt tttaataaat gatggttaaa aataaaatac gaggtgatac catgtatagt
    31141 gttataattg ttgcagcggg aagcggaagg agaatgaact tagatataaa caaacagttc
    31201 ataaaattaa gagaaaaaga aattattgct catacaattc aagtttttta tgaaaatata
    31261 aatatagatg aaatagtggt atgtataaaa aaagaagaag aagatttttt taaagaaaat
    31321 ataataaata agtataactt taaaaatata aaaatagcat atggcggaaa agaaagacag
    31381 gactcaatat ataatggttt aaaaaaatta gataaaaatt gtgatatagt acttatccat
    31441 gatggagcaa gaccatttgt cgaccataga ataatcaatg aatctataaa ggtagctaaa
    31501 gaaaaaaagg ctgtggttgt aggtgttcca gtaagtgata ctataaagat agtgtcagat
    31561 ggaacagtac aagaaactcc agaaagaaat ttgctgtggg cagcacaaac ccctcaaacc
    31621 tttgaatata atctcataat agatgcttat gaacaagcat ataagaacaa ttattatggt
    31681 actgatgatt caatgttggt agaaaatata ggtcaaagtg tcactatggt aatgggttct
    31741 tatgaaaaca taaaaataac tagtccagaa gatttaaata tagcagaaca aatattaaat
    31801 atggaaaaaa gagatgaagt taacagtaga aggagaatta tatgagaata ggattaggat
    31861 atgatgtaca caaattaaca gaggatagaa aacttataat cggtggtgta gagataccac
    31921 acgataaagg tttgttgggt cattctgatg ctgatgtatt gatacatgca ataatggatt
    31981 ctattttagg tgctctagca ttaggagata tagggaagca tttcccagat acagatgaag
    32041 aatataaggg agcagatagt atgaaattat tagaacatgt gtataatcta ataacaagta
    32101 aaggatataa aattggtaat atagacagta ctataattgc tcaaagccct aagatggctc
    32161 catatattga gagtatgaga agtaatatat caaaagtttt aaacacagac attgataata
    32221 taaacataaa ggcaacaaca gaagaaggtc ttggttttac aggagcaaaa cagggaatag
    32281 cttcacaaag tatttgttta ttattgttga caagtcagaa taattaatat attattagta
    32341 ataagtttaa tggatatcaa gtaataggcc tatatagaat atctataatg tatgaattta
    32401 agtgaaatta atataaatat aaaattagct atgataaaga aatagtaaaa tgatgaaatc
    32461 ttcacagaga gaaaacggtg gtgagagttt tcaagaggaa gtctttgaac ctgtctttta
    32521 gcttaaaggt ataaaaatct ttacggtagg aaccgttata ttcccaaaag agagctattc
    32581 atatagctaa ctagagtggt accgcggaaa ttaaaccttt cgtctctata cttgtataga
    32641 gatgagaggt tttttatatt ttcaggaagt taatattcag gaggaatcta ttaatgaaaa
    32701 tgtcaaaaat gtttatgccg acattaaaag aaatcccagc agatgctgag attacaagcc
    32761 atcaattaat ggttaggtca ggcatgataa aaaaaatgac ttcaggtgtt tataaccaat
    32821 taccaatggg gttaagagtg ttcaaaaaaa ttgaacaaat aattagagaa gaattaaata
    32881 aaaaagattg tcaagaaata ctttgtgcag ccttacttcc ttctgaatta tggaaagagt
    32941 ctggaaggtg gactgctatg ggtgaagaaa tgtttagact aaaagacaga acagaaagag
    33001 agtactgtct tgggccaaca catgaagaag cattcactga tataataaga caagaaatta
    33061 cttcatataa acaattgcca ctgaacttgt accaaataca agtaaaatat agagacgaga
    33121 gaagaccaag atttggtgtt atgagaacta agacttttac aatgaaggat gcctatagtt
    33181 ttgatgtaga tgataaaggt ttagataagt catatcaaga tatgtttgat gcatatgtaa
    33241 gtatatttaa tagatgtgga ttggagaata gccctgtaca ggcagattca ggagctatag
    33301 gaggttctac atcagccgaa tttatggtta agtcagaagt tggtgaagat gaagttgtat
    33361 tttgtagtgg atgtgattat gcagccaatg tagaaagagc agaatcttgt aatctagcat
    33421 cacaaaaaga agaaatgaaa gaattagaag aggttcatac accaggagca gctacaataa
    33481 aagagttaga agaattttta aaaacttctc cagataagtt tgctaaaact ttagtatatg
    33541 aggcagatgg aaaaacagtt gtagtcgttg taagaggaga tagagaagtt aatgaaatca
    33601 aagtatctaa tgccataggt tctgttatag aatttgctct tgctacagat gatgtagtga
    33661 gaaaagtaac taatgcagaa gtaggatttg caggtccaat aggtataaat gctgactatg
    33721 tatttataga taaagaaatt gttgaacaaa gaaacatagt tgttggggct aataaaactg
    33781 agtaccatat aaaaaatgct aactatggaa gagattttga aggaatagtt ggagacttta
    33841 gaaatgttca agaaggcgac aagtgtatag tatgtggtaa gccacttgaa atagctagag
    33901 gtgttgaagt aggacatata tttaaactag gaactaagta ctcagaatct atgaatgcaa
    33961 acttcataga caaagatgga aaatcaaagc ctatagtaat gggatgttat ggaataggtg
    34021 ttgaaagaac agcagcagct ataattgaac aacataatga tgagaaaggt ataatatggc
    34081 ctttgtcagt agctccatac catgttgtga tagttccagc aaatatgaaa aatgaagaac
    34141 aaatatcaat agctgaaaat atatataatg atttgcaagc tatgggtgta gaagttttat
    34201 tagatgacag agatgaaaga ataggtgtca aattcaatga ttcagaatta ataggaatac
    34261 ctatgaggat tacagtaggt aaaaatatta atgaaggtaa agtagaattt aaacttagac
    34321 ataaagaaga taaagagata attgacatag aagaaataaa tgaaaaagta aaggcagagt
    34381 ttatcaggaa taatgttagg ttaggataat aacttaaata agatattgta tagataatca
    34441 aagttgtact ttatagacac cattttatct atatataagg atataaaatg gtgttttttt
    34501 ataaaacaaa taaatgagga ggtaattaaa atggcaaaaa atgaaaaaca atttgttgaa
    34561 gaaataacaa agatggaaga tgattttcca caatggtaca cagatgtaat aactaagact
    34621 gacttagttg attatgcccc agtaaaaggt tttatggttg taaagccata tggatatgca
    34681 ttatgggaaa agatgcaaga atttatggat aaaaaattta aagaaactgg acataaaaac
    34741 tgttattttc cattattaat accagagagt ttattaaaca aagaagcaga acacgttgaa
    34801 ggttttgctc cagaagttgc atgggtaaca catggaggaa ataaaaaatt agaagaaaga
    34861 ttatgtgtaa gacctacttc agagactata atatgtacaa tgtatgcgaa atggttaaaa
    34921 tcatatagag aattaccata tctttataat caatggtgct cagttgttag atgggaaaaa
    34981 tcaactagac ctttcttaag aacatctgag tttttatggc aagaaggtca tacgttacat
    35041 gaaacagcag aagaagcaca agaagaaaca atacaacaat tagaagtata taaagcgcta
    35101 tgtgaagaat tacttgcaat gccagttgta gctggtcaaa aaagtgaaag tgagaaattt
    35161 gcaggtggtg aaagaacata tactatagaa gctatgatgc atgatggtaa agcattacaa
    35221 tcaggtacaa gtcacttcct aggtcaacac tttactaagg cttttgatat tacttttgca
    35281 gatagggaag gaaatttagc taatccatac catacatctt ggggagcatc tacaagactt
    35341 ataggtggac ttataatgac tcatagtgat aacagaggtt tagtattacc accaagagta
    35401 gctccaattc aagttgttat agttcctata gctgctaaaa aaggaaatgt aatggagact
    35461 gttgataaaa tatatgctga tttaaaagct aagggagtag ctgtagaagt tgatgataga
    35521 gataactata caactggatg gaaatttaat gagtgggaaa tgaaaggtgt tccagtaaga
    35581 gttgaaattg gaccaaaaga tatagaaaat aatcaagcta tggtatttag aagagatact
    35641 ttagaaaagg attctatgcc tttagaagga ttagctgatg ctatatgtga tttatttgat
    35701 gttatacaca atgatatgtt tgaaaaagca agaaaacata gagaagacaa tacatctata
    35761 gttgaaaata tggatgagtt tagaaaagct ttagaagaaa agccaggatt cataaagact
    35821 atgtggtgtg gagatgcaga atgtgaagct aagattaagg aagaaacagg agcaactata
    35881 agatgcttac cttttgaaca agaaaactta ggtcacaagt gtgtgtactg tggaaaagaa
    35941 gcagatagta tggtagtaat ggcaaaagct tactaaaata catttaaata aaaactgggg
    36001 tagaaagtat ttaatacttt atcccagttt tttgtttttt atgagtaata aaatgtattt
    36061 gtaactatgt cataagataa gtcatagata cttatattaa aaagaatata atagagaact
    36121 atttttaata attacatatt aatgaaagca aaatattttg ttatatagat tttcaataaa
    36181 gcaaacaata aatataaatg aatattaata aggagtgctt ttaattttta gaaaataaat
    36241 gacttaaaag aaagatttat gaaattaaaa ctaggatttt ctgatataat aaacatgtgt
    36301 atttttaaat aaaaaggata ttattattag atttgattaa aaataaactt gcaaaacaat
    36361 gtactagttt aatattatag ttatattgaa taaaatatca ggaggaagta aaaatgaatg
    36421 taagagtaag gtttgcacca agtccaacag gatttgtaca tataggtagt ttgagaactg
    36481 ctttatataa ctatttattt gcaaaaaaaa tgggcggaga atatatatta agagtggaag
    36541 atacagacca aagtagatta gtagaaggtg ctatagagaa tatgcttaat gctatgaaat
    36601 gggctggggt caaccatagt gaaggtgtta tattagatga tagtggaaaa gtagtacaaa
    36661 aaggagaata tggtccatat attcaatctc aaagattaga tatataccaa gaatatataa
    36721 agcaactttt agatagtgga aaagcttatt actgtttctg tacaaaagaa agactggatg
    36781 aagtaagaga tgctcaaaga gcagcaggag aaacagctaa atatgatggt cattgtaaga
    36841 atctttctaa agaagaagta gaagcgaata taaaagcagg aataccatat gttataagat
    36901 taagattgcc agagaatcat acaattaagt ttacagactt agttagagga gatatggaat
    36961 ttaatactaa tgacttagat gaccaagtat taatgaaaac agatggattt ccaacttatc
    37021 attttgcagt agttgttgat gactatttga tgaaaattac acatgttata agaggagaag
    37081 aatgggtatc atctactcca aaacatgttt atttatatga agcttttgga tgggaagcac
    37141 ctgtatttgt gcatttacca aatatactta ataaagaaaa gaaaaaatta agtaaaagac
    37201 aaggtgatgt agctgttgaa gactttaaga aaaaaggata tttaccagag ggattagtaa
    37261 actatgtagc attagttggt tggtctcctg aagataatca agaattgttt acaatggagg
    37321 aattagaaaa agccttctct gtagaaagag tatctaaaag tggtggagta tttgatactg
    37381 aaaaattaaa ttgggttaat cagcactata taaaagatgg tgatgatgct tatctaacag
    37441 acttagcaat accattttta atagaagatg gatttataac agaagaagaa gctactaata
    37501 aatatgattt cttaaagagt atgatatcag tacttaaaga gaaattacaa tatgtaaaag
    37561 aagttactga acatgcaagt atattttttg gagataaaat agaggtagaa actgaagagg
    37621 gaagagagtt cttaagatta gaacatatac ctactttaat agatgctttg agagaaaaaa
    37681 tagaaaaaac agaggtatta aatgctgagt ttgttcaagc tatgcttaaa gaaatacaaa
    37741 aagagtacaa aataaaaggg aaaaatttat ttatgggctc aagaataatt ttgacagggc
    37801 aaatgcatgg tccagattta ccaaaagtaa tggaagtttt aggaaaagaa acttgcttaa
    37861 atagaatagc ttatgtaaaa aataatatat tatagtcata aaagtccgct aatttagaag
    37921 cggacttttt ttgtgttagt atttggtgaa aatatctgct taagaaaatg aaggtattta
    37981 aggtaataaa tttaatatat aaaaagcaaa gcaaaaatat aaataaaata tgaataataa
    38041 actaataaaa tattaagcat agaagaaggg aatctattat tttagtttga tttaattatt
    38101 aagggggtaa ttactatgta tagtaatatt gatgatgtta aaaaggaatt aaaggagcta
    38161 tgcttagaat atgttacaat tttagaaaaa ttaaaagatg aaaaaatgat tacagaagaa
    38221 acttttgaaa agtgctcttc tcaaaaaaaa atatttttag aagaacaata gaggatggta
    38281 atagtattat tattatgtag tttgaaagat agtacgaaaa atgatagtaa tactattatt
    38341 tattgcaatt ttcaactata atataatata taatgttaag aagataattt ataaaaatac
    38401 agtgaggtga tgagtgtgaa agtttataat acattgacta gaacaaaaga agaatttgtt
    38461 ccattagaag aaggaaaggt aaaaatgtat gtgtgtggtc caacagttta taactatata
    38521 cacataggta atgcaagacc atttataata tttgatactc taagaaggta tttagagtat
    38581 agaggatatg atgtaactta tgtacaaaac tttacagatg ttgatgataa gattataaat
    38641 agaagtcatg aggagggaat atctcctgaa gaagttgcgg ctaagtatat aaaagaatat
    38701 tttgtagact gtgatgggct aggaataaaa agagctactg ttcatcctca ggttacagat
    38761 aatatacaac agattataga gtttataaaa gagttggaag ataagggata tgcatatgca
    38821 gtaaatggtg atgtatattt tgatacaaat aagtttgaag gttatggaaa actttcaggt
    38881 caaaaacaag aagatttaga ggcaggggct agaattgagg ttaatgacca aaaaagacat
    38941 cctatggact ttgttctttg gaaggcaaaa aaagaaggtg agccaggatg ggatagccct
    39001 tggggagaag gtagaccagg atggcatata gaatgttctg ttatgtctaa gagatattta
    39061 ggtgaaacaa ttgatataca tgcaggtggg caagatttaa cattcccaca tcatgaaaat
    39121 gaaatagctc aaagtgaagc tagaagtgga aaaacattct caaaatactg gatgcataat
    39181 ggatatataa atataaatga tgaaaagatg agtaaatcaa aaggtaattt ctttacagta
    39241 agagatatat caaaattata tgatttagag atagtaagat ttttcatgtt atcagcacat
    39301 tatagaaatc cagtaaactt tagtgatgag atgttaaatc aagctaaagc aggtcttgaa
    39361 agactatata atactaaaga aaaattagaa tttacgctaa gtaatttagt agaatctcct
    39421 ttaacagaaa aagaagtaga gcttgttaaa gaattagatg actttagaca aaaattcata
    39481 gatgctatgg atgatgatgt taatacagca gacgcagtaa gtgtaatatt tgaattagct
    39541 aagttaataa attctaatgt agatgaaaat tcttctttgg agtttgctaa aaaatgctta
    39601 gatgaattta atgaacttac aggagtatta aatattgtaa ataagaaaaa ggatactgta
    39661 ttagataaag acattgaaga attgatacaa aaaagaactg atgcaaagaa aaataaagag
    39721 tttcaattag ctgatgatat tagacaacaa ttactagata tgggaattgt attagaagac
    39781 acaagacaag gtgttaagtg gaaaaggata taaaaatgga aaaaactgaa ttagttacta
    39841 tgtcaccatt agttttagca tacttaggtg atacagtgta tgagacatat ataagagaat
    39901 atttaattag acagaataca caaagaaaag ttaatgattt gcataaacta gctataaagt
    39961 atgtaaaagc taaagctcag gcaactataa ttcatgaagt tgaaattgag ttaactgaag
    40021 aagagagtaa aatttataaa aggggaagaa atcaaaagtc aaatacttct cctaagaatg
    40081 cagatattat agactacaaa catgcaactg ggtttgaggc attagttgga tatttgtatt
    40141 taaataatga aatagagaga cttcaatata ttatcaataa aggaatcaaa attattgaaa
    40201 gagatatgta aatattaaag agtgttgtct taataataag taataaggca acactttttt
    40261 tataactaat gtataataaa tatatagaaa ttagtaatga gaaaggataa aaagttatga
    40321 aagtaaaatt aatatcacat acacctgaac cagaaaaagt aatagctatg gcagctaagc
    40381 tatgttattc accagttggg acagacgaaa tagaaaaaga cttaacagat gaaagtatag
    40441 agaaattttt aaatatgtta ttaagtatag gtcatgggtc aatattagaa catgcttcat
    40501 ttacattttc aatagaaggt atttcaaggg catgttcaca tcaaattgtt agacatcgta
    40561 tagctagttt ttcacaacaa agtcaaagat atgttaaatt agaacaattt gagtacataa
    40621 ttcctccaga aatagaaaaa atagaaaagg caaaagagtt atttatagac tccatgaaaa
    40681 aagaccaaga gaattatgat aagttagttg aaatattgtt tgaaaatcat tataatgacc
    40741 taataaaaaa cggtaaaaat gagaaaacag ctaaaagaca agctgagaag aaagcaatag
    40801 aagatgctag atacgtattt ccaaatgcat gtgaaacaaa gatggtattt actataaatg
    40861 ctagaagttt gtttaatttc tttgaacata gatgctgtga aagagcacag tgggaaataa
    40921 gaaatttagc tgtggagatg ttaagagagg ttaaaaaggt tgctcctata ttatttaaaa
    40981 agactggtcc aagttgtgta aatggaagtt gtccagaagg aactatgact tgtggagata
    41041 tagttcaagt tagagaaaaa tttaaggcct tgtaggaggt gaataatttg gcgagtatag
    41101 aaggaagaaa tccggtaata gaagcaataa aaagcgacag agaaatagat aaaatattaa
    41161 ttgcaaattc agctaaagaa ggttcaatta agaaaataat aggaatggct aaagataaga
    41221 atataattat tcagtatgtt gataaacata agttagatga agtaagtaca agtcattcac
    41281 atcaaggtgt aatagcttat gcaagtgagt ataagtatta tgaattagat gagctaatag
    41341 atttagcaaa gaataaagat gaagacccat ttttcattat attagatgag ataacagacc
    41401 cacataattt gggttcaata ataaggacag cagatgcagt aggagcacat ggagttatca
    41461 ttccaaaaag aaggtctgta cacataactc ctgtagttgc caaagcatct gctggagcag
    41521 tagaatatat gccagtttgc aaggtaacca atatagttaa tacaataaaa agactcaaag
    41581 aagaagggct gtggattgct gcagctgata tggatggaga aactttttat aaacaaaatc
    41641 ttactggtcc tcttggtgta gtaattggaa gtgaaggttt tggaatatct agattggtta
    41701 aacaaaactg tgactttata gtaaaaatgc caatgatagg taatgttaca tctttaaatg
    41761 catctgtagc aggtggaata cttttatatg agatattcag acaaagactg gataaaagta
    41821 aataggcatg aaaaaaaata taaatcatta cttaataata gatggctaca atattataaa
    41881 tgcgtgggac aatttgaaag aactggctaa agaggactta gaagattctc gagaaaagct
    41941 tattgatgac attatagaat tttctgagtt tatgggttat aagactataa tagtttttga
    42001 tgcttataat gttaaaaatt ctcgagaaaa agttgaaaaa agaaaacaca taacaatagt
    42061 ttatacaaga gaacaccaaa cagcagatag ttatatagag aaatttataa cttctttatc
    42121 aaagtatgat gatgtaaaag tagccactaa tgactatgca gaacagcaaa tgattttagg
    42181 aaaaggtgct actagaatgt ctgcaagaga attaaagtta gagttagatc gttccaagaa
    42241 taaaatgaag gaaaaaaata tcggtttgag gaaaaaaatt cagcgaaatt ggttggagga
    42301 aaggttagat aaagaaacat tgtcgaaact tgagaacatt cgtagaaagc gttgaaatta
    42361 ctaggttctt tagactataa tatacctata aatttgtttt atatatgggg gagatttaca
    42421 tgttggtagc aaaagaaaaa agttatgagt tagtggacaa ttgtcagcag gatgagtata
    42481 acattgtatt aagagcaagt gaaggggata aaatagcact agagtacatt attactaaat
    42541 acagaaattt tgtaaaggca aaagcaaagt catatttttt aattggagca gataaagaag
    42601 atataataca agaaggaatg ataggccttt ataaggcagt tagagatttt gatggaagta
    42661 agaccaattc atttaaatgt tttgcggaga tatgtataac aagacaaata ataactgcta
    42721 taaaaactgc aacaagacaa aaacatatac ctttaaattc atatgtttct ttgaataaac
    42781 caatatatga tgaagagtca gacagaacac ttttagatat tatagctaca agtatagtaa
    42841 cagatccaga agagcttata attagtaaag aagagttaaa aaatatagaa tcaaaaatga
    42901 acgaattgtt aagtgacttg gaattagaag tactagaatt atatttaaat ggaaagtcat
    42961 accagtttat agcggacaag cttaaaagag atgtaaagtc aatagataac gctttacaaa
    43021 gggttaagag aaaattagaa aaacatcttg aaaacagaaa tgattaatag taaaatactt
    43081 accataagct tattgtgagc aaaattaatt tatatcgaaa gataagggag gaaattcaaa
    43141 atggctaaag ctaaatacga aagaacaaaa cctcatgtta atatagggac aataggacac
    43201 gtagaccacg gtaaaactac attaacagca gcaataacaa aaacattata tgacagatat
    43261 caattaggag aagcagtaga tttcgcaaac atagataaag ctccagaaga aagagaaaga
    43321 ggaatcacaa tatcaacagc acacgttgag tatgaaacac caaatagaca ctatgcacac
    43381 gttgactgcc caggacatgc tgactacgtt aagaacatga taacaggagc agcacaaatg
    43441 gacggagcaa tattagtttg ttcagcaaca gatggaccaa tgccacaaac aagagagcat
    43501 atactattat caagacaagt tggagtacca tatatagtag tattcttaaa caaatgtgac
    43561 atggtagatg atgaagagtt attagagtta gtagagatgg aagtaagaga tttattaaca
    43621 gaatatgatt tcccaggaga tgacactcca atagtaagag gttcagcatt aat
//
LOCUS       DAYAKB010000029        41021 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.029, whole genome shotgun sequence.
ACCESSION   DAYAKB010000029 DAYAKB010000000
VERSION     DAYAKB010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41021
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.029"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            136..2637
                     /locus_tag="ACGI3L_001861"
     CDS             136..2637
                     /locus_tag="ACGI3L_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFG9197570.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVKNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            2797..3465
                     /locus_tag="ACGI3L_001862"
     CDS             2797..3465
                     /locus_tag="ACGI3L_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197571.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            3449..4726
                     /locus_tag="ACGI3L_001863"
     CDS             3449..4726
                     /locus_tag="ACGI3L_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9197572.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            5127..5348
                     /locus_tag="ACGI3L_001864"
     CDS             5127..5348
                     /locus_tag="ACGI3L_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197573.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(5637..6401)
                     /locus_tag="ACGI3L_001865"
     CDS             complement(5637..6401)
                     /locus_tag="ACGI3L_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFG9197574.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            6675..7349
                     /gene="fsa"
                     /locus_tag="ACGI3L_001866"
     CDS             6675..7349
                     /gene="fsa"
                     /locus_tag="ACGI3L_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFG9197575.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVGKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(7471..8865)
                     /locus_tag="ACGI3L_001867"
     CDS             complement(7471..8865)
                     /locus_tag="ACGI3L_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFG9197576.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(8943..10289)
                     /locus_tag="ACGI3L_001868"
     CDS             complement(8943..10289)
                     /locus_tag="ACGI3L_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9197577.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      10539..10641
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            10735..12111
                     /locus_tag="ACGI3L_001869"
     CDS             10735..12111
                     /locus_tag="ACGI3L_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFG9197578.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(12225..13370)
                     /locus_tag="ACGI3L_001870"
     CDS             complement(12225..13370)
                     /locus_tag="ACGI3L_001870"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9197579.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIILDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            13623..14330
                     /locus_tag="ACGI3L_001871"
     CDS             13623..14330
                     /locus_tag="ACGI3L_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197580.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            14377..15972
                     /locus_tag="ACGI3L_001872"
     CDS             14377..15972
                     /locus_tag="ACGI3L_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197581.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLMVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            16075..17157
                     /locus_tag="ACGI3L_001873"
     CDS             16075..17157
                     /locus_tag="ACGI3L_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HFG9197582.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            17306..17467
                     /locus_tag="ACGI3L_001874"
     CDS             17306..17467
                     /locus_tag="ACGI3L_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HFG9197583.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            17808..19076
                     /locus_tag="ACGI3L_001875"
     CDS             17808..19076
                     /locus_tag="ACGI3L_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFG9197584.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            19271..20059
                     /locus_tag="ACGI3L_001876"
     CDS             19271..20059
                     /locus_tag="ACGI3L_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HFG9197585.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSIRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            20059..20508
                     /locus_tag="ACGI3L_001877"
     CDS             20059..20508
                     /locus_tag="ACGI3L_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFG9197586.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            20512..22776
                     /locus_tag="ACGI3L_001878"
     CDS             20512..22776
                     /locus_tag="ACGI3L_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9197587.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            22916..23227
                     /locus_tag="ACGI3L_001879"
     CDS             22916..23227
                     /locus_tag="ACGI3L_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197588.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            23513..24013
                     /locus_tag="ACGI3L_001880"
     CDS             23513..24013
                     /locus_tag="ACGI3L_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFG9197589.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            24070..25056
                     /locus_tag="ACGI3L_001881"
     CDS             24070..25056
                     /locus_tag="ACGI3L_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197590.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            25106..25828
                     /locus_tag="ACGI3L_001882"
     CDS             25106..25828
                     /locus_tag="ACGI3L_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HFG9197591.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            25857..27791
                     /locus_tag="ACGI3L_001883"
     CDS             25857..27791
                     /locus_tag="ACGI3L_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9197592.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            27784..29052
                     /locus_tag="ACGI3L_001884"
     CDS             27784..29052
                     /locus_tag="ACGI3L_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HFG9197593.1"
                     /translation="MSKNIYVKETYEWIRIGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
     gene            29379..30419
                     /locus_tag="ACGI3L_001885"
     CDS             29379..30419
                     /locus_tag="ACGI3L_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197594.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            30775..32097
                     /locus_tag="ACGI3L_001886"
     CDS             30775..32097
                     /locus_tag="ACGI3L_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFG9197595.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            32394..33755
                     /locus_tag="ACGI3L_001887"
     CDS             32394..33755
                     /locus_tag="ACGI3L_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFG9197596.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            33828..35222
                     /locus_tag="ACGI3L_001888"
     CDS             33828..35222
                     /locus_tag="ACGI3L_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9197597.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            35284..35754
                     /locus_tag="ACGI3L_001889"
     CDS             35284..35754
                     /locus_tag="ACGI3L_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HFG9197598.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            35757..37973
                     /locus_tag="ACGI3L_001890"
     CDS             35757..37973
                     /locus_tag="ACGI3L_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9197599.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            38056..38727
                     /locus_tag="ACGI3L_001891"
     CDS             38056..38727
                     /locus_tag="ACGI3L_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9197600.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            39090..40304
                     /gene="dpaL"
                     /locus_tag="ACGI3L_001892"
     CDS             39090..40304
                     /gene="dpaL"
                     /locus_tag="ACGI3L_001892"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HFG9197601.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            40431..>41021
                     /locus_tag="ACGI3L_001893"
     CDS             40431..>41021
                     /locus_tag="ACGI3L_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9197602.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT        15916 a         4429 c         7193 g        13483 t
ORIGIN      
        1 aatattgatt taatatacct atagggggta taataaaaat atagatttct aaataagtaa
       61 tttatcaata ttacatatca aaataaaacg ttacaaatta gctgaaaata tattgaaaga
      121 aaggaagatt ttattatgag ttcaaataaa gtggtagaaa gttataaaat tacaggtatg
      181 acatgtgcag cttgtgcaaa ggcagtagag agagtaacta agaagatgga tggagtatat
      241 gaccaaagtg taaatatagc tactgaaaaa cttaaaatag aatatgataa ttctaaggtt
      301 aattttgatg atataaagca ggttgtagaa aaagcaggat atggaattat aaaggaagaa
      361 agtaataaaa aaattgatat gaaaattgat ggaatgacat gtgcagcttg tgcaaaagct
      421 gtagagagag tggtaaaaaa attggatgga gtagaaagta ttagtgtgaa tattgcaaca
      481 gataaagcta atatagacta tgacccatca aaagtaaaat tatctcaaat aaaagcagct
      541 attgaaaaag ctggatataa accaatagaa gaggtaaaaa ataaggttga tgtggatgaa
      601 gataaattga gaaaagaaag agaaatgaag tctttatttg ttaaatttat agttgcaata
      661 gtatttgcag tacctctgtt ttatatagca atgggaccta tgataataaa gcctataggg
      721 ccatggcctt tgccagaaat tataaatcct atgacaaata cttttaatta tgcattaatt
      781 cagttaattt tagtaatacc agtaatgata gctggttata aattttatat aaatgggttt
      841 aaatcacttt tttctttaag ccctaatatg gattctttag ttgcaatagg aacattagcc
      901 gcatttttat atagtctata tacgacacta caaatagcca atggacaaat tcaaggtatg
      961 caccatcatc agttgtatta tgaaagtgca ggaataataa tagcacttat cttacttggt
     1021 aaatatttag aatcaaaatc aaaaggaaaa acatcagaag caattaaaaa gcttatgggg
     1081 ctacaaccta aaactgcaat agtgttagtt gatggtaaag aagttgaaac tcctatagaa
     1141 gaagtagaga taggagatat actattagta aaaccaggaa ctaaaatacc tgtggatgga
     1201 gttgtaatag aaggatatac atcagttgat gaatcaatgc ttacaggtga aagtatacca
     1261 gtagaaaaga atgttggaag taaggtgaca ggagctagta ttaataaaaa tggtgttatt
     1321 aagtttaagg ctgaaaaaat tggtggagat actgctcttg cccaaataat aaagttagtt
     1381 gaagatgcac aaggtacaaa agcacctatt gctaaacttg ccgatactgt atctggatat
     1441 tttgtaccaa tagtaattgc aatagctgta gttgcatcat tattgtggtt tttaatagga
     1501 ggaaaagata tagtatttgt acttactata tttatatcag tacttgtaat tgcttgtcct
     1561 tgtgcattag gattagcaac accaactgct ataatggttg ggactggaaa gggcgcagaa
     1621 aatggaatct tgataaaagg tggagaggca ttagaatctg cacataaagt aaatacagtg
     1681 atatttgata aaacaggtac tataacagaa ggaaagccaa aagtaacaga tatagtatta
     1741 aataataatg taaaagaaga atatcttatc aagattgctt caagtgcaga aaaaggttca
     1801 gaacatcctc ttggagaagc aatagttaag tatggagaag agaagaatat aaaatttgaa
     1861 aaagttgata attttaaagc cataccaggt gctggtatac aagttactat taatgatgaa
     1921 agtatattac ttggaaatag aaagcttatg aatgacaata atataaagct tggggattta
     1981 gaagaaaaat caaatatatt ggcaagccaa ggtaaaacac ctatgtatat agctgtagat
     2041 ggaaatttat caggtataat agcagttgca gatgtagtca aagaaagtag taaaaaagca
     2101 atagaaatac ttcatgatat gggaataaaa gttgcaatgg taactggaga taatgcgaaa
     2161 actgcaaatg ctatagcaaa tcaagtcggt atagatatgg ttttggcaga ggttttacca
     2221 gaagataagt caaaagaagt tgaaaaacta caaaatcaag gaaagtttgt tgcaatggta
     2281 ggggatggaa taaatgatgc cccagctctt gcaaaagcag atatagggat agcaatagga
     2341 agtggaacgg atgtagccat tgaatctgcg gatatagtac ttatgaagag tgatttaatt
     2401 gatgttccaa cagcaattaa acttagtcat gaaactataa aaaatataaa acaaaaccta
     2461 ttttgggcat ttggatataa tacaattggt atacctgtag cagcaggaat attatatgta
     2521 tttggaggac ctttattaaa cccaatgatt gcagcagcag caatgagctt aagttcagtt
     2581 tcagtcgtat caaatgcact tagacttaaa aacttcaagg catataagag agattagatt
     2641 aataaattaa ataaaatgta tccaaaagag ctatctttaa attaaaagga ttaatttaca
     2701 aattaagata gctctttttt catgtaaaat tcacaacaat aagataaaat ataagtaata
     2761 tacgaaattt taaataaaat agaaaggatt gatagaatga attcgtcaat acttgtaatt
     2821 gaagatgatt caaatataca agagttaata tcagaatttt taagtgcaga aggttatcaa
     2881 gttgatacag caaatgatgg gttggaaggt atacaaaagt ttaagcaagg aagttatgat
     2941 ttagtaatat tagatataat gatgccaaac ttagatggtt atggagtttg taaaatgata
     3001 agaaagtcat caagcgttcc aattatattt ttaactgctt taaatgatga aggagaccaa
     3061 cttaaagggt ttgacttaga atgtgatgat tatataacaa aaccattttc atttaatctt
     3121 cttataaaaa gagtagaagc aattttaagg cgaagtaaca agactataaa tgacaaattt
     3181 atagtttttg aaaaattaaa attagattta aacacatata ttgcagagat agatggagaa
     3241 cctatagaac ttacactaaa agagtttaat atattaaaag ctttgataga aaagtatcca
     3301 caagttataa ctagggaagg tcttttggat agtatatggg gttatgacta ttatggagat
     3361 actaggattg ttgatgcaca tataaaaaat ataagaaaaa aaatatcatt accatatatt
     3421 aaaactgtaa aaggaatagg atatacactt gagaaggata tttgataagt gggaaaagtt
     3481 aagtataaag tataagttat tttcaataac gacatcatta ttaatagcat tagctttaat
     3541 aatatatcta attttatatt ttttattgcc atcatattat catgagtata aaattgagtc
     3601 tcttcaagaa agtttgaaat ctttagtaga tagttcaatt catttcgata catatacttt
     3661 agaagaaaga ctttattata tggctaaaga ccaaaatttg gctattttat taaaagataa
     3721 ccaaggtaaa attgtatatg gtaagaatga agtagttatt ttaagatata gtaagtacat
     3781 gattaatagt cttgaggatg agtatagaac ttctatacct atatatacta aagatgcaaa
     3841 agatggtcca tatactttag aactcgttat gccattacaa ccaattgacg aagcaaacga
     3901 agttataaga aaactaatgc catacatcat atcaatagca atattgatag cgattattgg
     3961 agcatatata tattcaattg taataacaaa gcctcttata aacataatag agagtgagag
     4021 agaacaggaa tatagaagga aggattttgt tgctacaata tcacatgaac taaaaactcc
     4081 aataaccata ataagtggtc aaattgaagg tatgatttat agtgtaggta agtataagga
     4141 tagggatact tatctgaaaa aatcgtatga gtgtacacaa gaattaaaag atttagtaaa
     4201 tgaaatgata gaggtttcaa aatcagaaat acttgaaaaa gatttgaaat tggtatcaat
     4261 aaatataagt gaattattaa atagacttgt aaagagacaa gtatttttaa tagaagaaaa
     4321 acatatgaaa actattttaa aaatagaaga aaatttggaa attaaagcag accaagagag
     4381 aataactaag gcaatcaata atataataaa taatgccata aaatattctc ctgaagaatc
     4441 agagcttata attagactct atgataaaaa taaacgaata agtaaaaaga cttctaatca
     4501 aagagtggtt ttagaaattg aaaatactgg tgtaactatc gagaaacgtt atttagaaga
     4561 aatatttaat ccattttata gaatagaaaa atctcgttcg agaaaaactg gaggaagtgg
     4621 acttggactt tatatagtca gccaaatttt taaaagtcat gggtttgatt atagcataaa
     4681 aaacaaagaa aactctgtag tattcacagt agaatttaaa aattaattac ttattataaa
     4741 gaatatataa ctttcaataa tagttcattt taaaatcaca aaaaattcat aatgaaactg
     4801 tattatataa atataaataa gcttaaaacc ataaaataca ccaactataa tgatgagatt
     4861 tccttacatc ctccatataa gtcatcatta tagtaaccca acaattaagt tactatgaat
     4921 ttaaaaaata acaccgagca tataatctat gcttagtgtt atttttattt tgaaataaaa
     4981 aatatttaat ttattgaaat gtatagattt agatagttta aactatattt aagacttaaa
     5041 aattataatt gatattacaa ataaatatat gtactttggg aaaaataaat ataggaagta
     5101 ttatatttac agaggaggta gttttgatgg atagattaaa aagagatatg aaaaatatga
     5161 aagaagattt aaaagaaggt gttaaaaaga cagcttatgt tatgaaaaat acagctgaag
     5221 atttgaaaga tgatgcacaa ggtgctatgg taaacttaga aatgaaaaaa gatgagatga
     5281 tggaaagata tgaacaaaag aaattttcta aagaattaga gaagcaaatg aagaatgaaa
     5341 tgaaataagc ttttatttat gaataacaaa ttattgtatt catataaaaa gtagccagta
     5401 atattaaata gtttatttaa ggaaatagac tttctaaaaa taactgtatt agatttagaa
     5461 agtctatttc aaattagttt tataaataga cataaggata aagtagatgt tatagaacta
     5521 gattttaaaa aatagatact aaggataaaa taaatattat agaaatatgt ttttaagaat
     5581 atttatcaaa taaaaattta tatttataag aaatcctata aaacatataa ttaaacttat
     5641 aaaacattta cattaaattc tgataaaata tctactatat caggagtagg cgttttttct
     5701 gtaattatag aactaatatc ttctaaatga gcaaacttga aatttccatc aaatttaaac
     5761 tttttatctt ccataactat aaatactttt ttacttgaat ttattatagc cttcttcgta
     5821 agaccatctt caatttcaaa agttgtaagt gaagagttga atacatctac tccacaactt
     5881 cccataaaag tcttatcaaa cttatatttc gatataaact ctatagttgg agtaccgaca
     5941 aaaccgtcta aactgagatt taataaacct ccagtggaaa ttatatttaa attatttggt
     6001 tttgaagtaa ctacatttag tatatccagc atatttgtaa caagtgttac ttttttatta
     6061 ctttcagcta acaacttcgc aagcaagatg ttaattgtag agatatctaa aaatatagtt
     6121 tctctatctt caattaaatt aaatgctttt tctgctatta ttttctttgt tggaatatta
     6181 atttcttttc tgtcttttgt atcctgattc tctagtgttt ctctagctag tacagctcct
     6241 ccataaattc ttcttattga agaaatcttt tctatatttt ttaaatcttt tcttatacaa
     6301 tcttctgtaa cattaaattt agaactgagc tctttgacag taactctacc ttcttttttt
     6361 aggatattta atatagcttg gattctttct tctgcaaaca ttttctacct cttttcgcaa
     6421 tatagtatta tagtaaatat tataagataa aatacaatat atcaactatt ttaacatgaa
     6481 atacaaaatt aatttaatat aaaaagtatg ttttttctaa ctatatattt agaatttagt
     6541 aaataaaaaa attataaaac taagaaggaa aagtaaaaca ataataaaaa ataaaaaaca
     6601 ataagcaaaa tgttgaaaat aataccaaat caatatataa taagaataaa gaaagattaa
     6661 agggggatat tttaatgcaa ctaatcttag atacaggtaa tgtggaggag attaaggagt
     6721 tatgtacttg tttaccaata gatggtgtaa ctacaaatcc aagtattgtt tcaaaagaaa
     6781 aaaagaattt taagcaactt ataaatgaaa ttggtgagat tataggtgag gatatgccta
     6841 tacatgctca agtgttaagt acaaagtatg aagaaatatt agaagaagca ttatatataa
     6901 gtagtttgag aaaaaatata tatgtaaaaa tacctgtaac acaagatggt ttaagagcta
     6961 taaaagacct tcacagaaaa ggtgtaaaaa taactgctac tgcaatattc actgctcatc
     7021 aaggtttttt agctgcaaag gctggagcaa attatattgc accttatgta aataggcttg
     7081 ataatatatc tggtgatgga gtagctatgg tttcagaact tataaaaata atagatactt
     7141 ataaaatgga tacaaaagta cttgcagcca gttttaaaaa tgcacaacaa gttatagaat
     7201 taatgcaaca tggggtgcat agtgttacag taccatatga tatttgtaaa tctatgatga
     7261 atcatccatt aactgattgg agtgtaggta agtttataga ggattgggag aatacttttg
     7321 gaaaaggaag taaaacaaat aatatttagt attatggtaa aagagtagtt ttgtccaatt
     7381 tcacaagaac ttatataaaa agatgaaaat atgaattttc tttttaataa tttcgttatt
     7441 atcttaagtt aattcatatt ttcatctttt ttagatttct agtcctataa atttccacca
     7501 agggaatgtt atacatatta ttataaagta ggttaaagga atcaaagtta aaccgtattt
     7561 gaaaataacc ttgctattat acagattttc accatgacca accattattg tagcatgatg
     7621 aaatggtaat atgtactgta tgcttactat aatgtagaca aatagacata aagtaacact
     7681 attttccttt agtatatgta aacttccaag taacggtatt actacagatg atgtagtgac
     7741 agcacttcca agacatatat tcaagattat tgtgagagtt atcaaaaaca atattgaaat
     7801 aatttctgaa gagtttggta taaactttat caaataattt cccattatat ctacaactcc
     7861 agagtacttt aacactcctc caattgaaaa tgctgctata aaaaaaataa ggaccttcca
     7921 atttatttct tttaaagtac taaatccaac tatttttctt agtaataaaa gaagtacaca
     7981 aattgacatt ataattaatg tgtttatgtt atgtatgaac tgagttaaaa acataaaaaa
     8041 cattattcct aggcataaaa atacgtgttt ttgctctttg tttagcaaat taaattcttt
     8101 ttttaaatta gaatatgaaa aatgaagttt attaccctca agattttcat tagaaataaa
     8161 ttttattgaa tgcaattctt ttttaaagac aaagataaat aaaaaataag ttataaaaca
     8221 agtaattata gttggaacag acatataaaa agcccattga ccccaattta tattacaatt
     8281 tccaagttct agtacaacat aatttagaag ggtgtctcca tttacaaaaa acattgatgt
     8341 aaaggtagat gctgtaaata tactaaataa aagtatagat tttgaatctt cagttatctg
     8401 ttgttctttt aaaaactcct tgtaaaaagc agatacaaga ataacccttg gaaatggttg
     8461 tgggataaaa aatattaaaa gtatacctaa aatatacgat aaaagaatca tttttttagg
     8521 ggtatttaca gtatttaaaa ttaacttctc agaaataatt tttgcgacac ctgtttttgt
     8581 aactgcatta gtaattatgt atgcaagaat tattatgtaa aaattttctg taaataaaaa
     8641 ctgtaaaata acctttattg gtgcaatgtt aaatataaac gctagaatta caaaaaacaa
     8701 tgcaacaaaa gttttttcaa ctgagtctac agcccatatc aagatagtta aaaaagataa
     8761 gcatatagaa aattttatgt tgaaactgta attaagagag aagtagagaa ttatggtagc
     8821 tataacagtc atataaaatt gttttggctt aagaataata cccattttta tattcacctc
     8881 cataatttat tatatcataa tggaggtgaa tacaatgaat gtgaatacat tttataaaaa
     8941 gattattcat tgattctatg atttacaata gctttagttt tccaatgtcc tttcttatag
     9001 tagataactg taacaataag acctaaagtc caaccaaaag gaatacccat ccaaattccg
     9061 tctgttccaa aaaatttaga aagcatataa gaagctggaa gtcttccaag ccataaagat
     9121 actattgagc ttataagtgc aaacatggaa tcaccagcac ctttcattgc acttgaaagt
     9181 acaaaagaag ttccaataaa taagaagaat ggtcctatta taaataagta agaagagcca
     9241 attttaatga catctttatc agtattgaat agagcaatta gattttccct aaatagcaaa
     9301 attaaagcaa taactgtaac tgctaaaact aaggtcattt ttatagattc tcgaatgcct
     9361 tttttaactc tttcattttc tccagcacct atgttttgag caacaaaagt agaaacagca
     9421 gaaccaagat tcataatagg taagcttata aaattttcta tcctaagacc agcaccaaaa
     9481 gctgccatag cagatgtacc ataactatta actaaaaatt gaagagccat atttccaatt
     9541 gaaaacaaca tttgttgaac tccacttgga agtcctaatc taagtccatc tttaaatatt
     9601 ttgttatcat atacaattcc tttgatttta aatttaagca cttcatgttt tttatttaaa
     9661 taaattatac ttattataaa tgatactgcc tgagccatta tagtggcaag tgcaacgccc
     9721 tcaacaccca ttcttagcac tacaataaaa gttaagtcta aaactatatt tagaattgtg
     9781 gctattatca gaaaataaag tggagttact gaatctccaa gtcctctaag tattgcactt
     9841 actgaattat atccagcaga aaataatatt ccactaaata ttatagtaag atacaatttt
     9901 gattgagcaa aaacggattc tggtgtattc ataagcttaa gcattgggcc accaaatact
     9961 attccaagaa tacttattaa tatagaacca ataaataaaa gtatatatgt agtatcaata
    10021 gtagctttta ccttttttaa atctcctgag ccataaaatt gtgacactaa aatagaaaat
    10081 ccaaggctaa cacccataag cgctgccacc aataaaaaca ttatagggtt agctccagag
    10141 actgccgcca ttgcttcttt tccgataaat ctaccaacta ttatactgtc agctgtattg
    10201 tatagttgtt gaaataaact accaataagc ataggcatgg caaaaaagaa tatggacttt
    10261 ccctcatgac ctgtagttaa atctttcacc ttattcctcc aaataaaaaa attattaatt
    10321 tattatagta taatcttaac ataaacttta tatccaaact ataaataaat tgtatcaaaa
    10381 tatcatatat ttttttaaaa tgtaaagaat ataattataa tttgaattta ataaatcaat
    10441 atttaatata atcgaatatt aatacaaaat caatacaata tatacgtata tattgacaaa
    10501 attaattata taaattaaaa taatattcgt aaagaaaaat tcatgttttg tactgtataa
    10561 catataattt tgacaatatg ggtcataagt ttctaccgga ataccgtaaa tattctgact
    10621 atgtatacta ttatttagtt aattaaatat ttaattaact gaattatgaa ggatacggct
    10681 cagcttatca actactgtgt cgtttttttg taaaatttaa taggaggtgt tgttatgcaa
    10741 acaacaaaca gtagtactat gcagaaactt tttccaattt tgactaataa aaatgtcgac
    10801 atgaagaagg aaataattgc aggagtaact acttttttaa ctatggctta tataatagct
    10861 gtaaatccaa atattttatc tgagacaggc atgcctgcag gtgcacttgt tacaggtact
    10921 tgtttagcag cagcatttgg atgtatttta atgggtgtag ttgctaacct tccttttgct
    10981 ttagcatcag gtatgggtct taatgcattt tttgcatata cagtagtttt acaaatgggt
    11041 gttccttggg aagtagctct tacagcagta tttgtagaag gtattatttt tatagtatta
    11101 tcagtaagtg gagttcgtga ggctgttgta aatgcgatac caaaaaatat gaaattagct
    11161 gttacaggtg gtataggaat atttattgca cttataggtc tagttaacag tggaattgtt
    11221 attggagacc aagccactct tatcaaaatg ggtagattta caccagcagt aataataact
    11281 tgtgtaggat taataattat tgctgtatta gataaaaaaa gagttaaagg ttctatactt
    11341 tttggaatag tagtgagttc attacttgct tgggcatttg cttttataaa tccagagtat
    11401 gcacaaaaat taggtatata tttacctggt ggattattta aattcgaaag tttagcacca
    11461 atagcaggta aaatagattt aggatatgta ctacatccaa caaatatagg tggtttttta
    11521 gtagtagttt gtacattttt atttgttgat ttttttgata cagtaggtac attagttggt
    11581 gtttgttcta aagcaaacat gttagatgaa aaagggaatg ttcctaatgt aggtagagcc
    11641 ttacttacag atgcggttgc aactacagtt ggtgcaggac ttggagtatc tacagttaca
    11701 acttatgttg agagttcaac aggagttatc gcaggtggaa gaactggatg gacagcaata
    11761 acagttggaa ttttattctt agctgcaatg tttttctctc ctgtatttat agcaattcca
    11821 tcatgtgcta cagcaccagc tttaatatat gttggatatt taatgcttgg tacagttaag
    11881 gatatagagt ttgataatat aactgaaggt gttccagctt ttgttactat tgcttgtatg
    11941 gcattaacat atagtatagg tgatggttta actttaggta tattaactta tgttttcgta
    12001 aatatatttt ataatatatt tggagctaaa aaggcagaag acaaaaaaca tgtttctgta
    12061 gtaatgattg ttctggcaat attatttata ataaaacttt ggctactata ataggtatta
    12121 tttaaaattt taatttaata taaaataaag ggctgtaatt tattatcaat tgtgatgata
    12181 aactacagct cttttgtatt tgttgtattt ttgtatttat tgtattattt aataatgtct
    12241 attagttctc cattttgtaa agttttaggt gtaattacta tattgaactc tttttgcaaa
    12301 tcttttataa tatctaattc tttttttgtt attattgaga ttgtgttacc acttcgattt
    12361 cctctagcag ttcgaccaca tctatgcagg tattcatttt tactttttgg aaaatccaag
    12421 ttaaaaacat gacttacatc cacaatatct agtccacgag cagataaatc agttgtaatt
    12481 aaaatctttg ctttaccaag tttaaattta tttattgcat tctttctatc ttctttttcc
    12541 atatttccaa aaattcctat tgctttgtaa ttatgataat ttagttttga tactaggact
    12601 tctatatttt tttcattatt tacaaataca atagcttttt ttggatttgt agctgctaat
    12661 gcctttctaa gaaaagtaaa tttatccctt atctcaccta ataaatatga gtgattgatg
    12721 ttaggattta tttgtgattt ttcctttgtt tttattattt caaactcctt cataagttta
    12781 tcacaaattt ttatagtgct atcagtaaga cttgcagagc atcctataat ttgtctatct
    12841 cttaacgttg ttcttattat gtcttctata caagttatat tttttccatt caatagattg
    12901 tccacttcat ctaagataat agtttttata ttatgtgatt ttagtttctt ttgttttatc
    12961 aagtctaaaa ctcttccaca agagccaatt actatgtgtg gttttactgc ttttatattt
    13021 tttatttgtt tttgtatatt gacctcccca attaaagcta aagaagtaac ggagagttct
    13081 gcatttttag ccaataattc aacctggttt gtaatctgca ttactaattc atgcgtaggt
    13141 gcaagtataa gagcttgtgt ttctcttttt gatgtatcaa ttttttcaaa tataggtaaa
    13201 aggtatgcta gtgtttttcc tgttccagtc tgtgaattaa tcaataaatc cttattttga
    13261 attatattcc ctataacaag tgactgaact tctgttggag aagttatgtc ttgttttttg
    13321 agtccatcta ttagagtgga acttattttt aattgttcaa atgtattcat attttactcc
    13381 ttatatttta ataattatag tcaactattt tttattatac attgtttatt caaatcgaac
    13441 tatatattct tttataatta tgtgtaattt gaaagtaaat atcaattata tttatacctt
    13501 tatatttctg atacctttgc attttataga tttctaaaat aaacaaataa aagttgtaat
    13561 tgtttgatat ttgttatata ttgtatataa caaatattaa aactataata tggagggaaa
    13621 ttatgttaaa agtaatcaat gtatctaaat catataaaaa taaaaaagta gtaagtagtg
    13681 tctcatttga tgtaaatgat ggagagcttt ttgggtttat aggacataat ggagcaggta
    13741 aaactactac tattaaagca attgttggaa tacacgattt tgaagaggga gaggtactaa
    13801 taaattctaa atctataaaa aaacagcctg ttgaatgtaa aaaggaaatg gcatatatac
    13861 ctgataatcc agatttatac gagtcattaa ctggtataca ataccttaat tttatagctg
    13921 acatatttga agttgccaaa gataaaagag aagagttaat aaaatattat tcaaataagt
    13981 ttgaactcaa taaagcatta ggagatttaa tatcttcata ttcacatggt atgaaacaaa
    14041 aattagctat aatttcggct ttgatacaca gcccaaaaat cttaattctt gatgaacctt
    14101 ttgtaggtct tgacccaaaa gcttccttta tattgaagga aattatgagg gagttttgtg
    14161 acaaaggtgg ttgtatattt ttctcaacac acgttttaga agttgctgaa aaaatttgtg
    14221 ataagattgc cataataaaa gatggaaata taattgctta tggaactaca gaagaagtta
    14281 agggaagtaa ttcacttgaa agtatcttta tggaattaat agagaaataa aatgtttttt
    14341 atacaatata gtgtctaaag tgaggaatga taaaatatga gcaatctaag tatattaata
    14401 aaaactaata taataaatga atttaaatta aatgcgttaa aaaaagctga tggtagagaa
    14461 aaacaaaaaa taatgggaat gatgctttca gttgttataa tagcgggtct attaattttt
    14521 tatgtaacaa gcttaagtct ctctttagtt gatatcttaa agcaaataaa tcaactggaa
    14581 atgctactga tatttggttt tggattatca acattaacaa ctattgttac atcattatat
    14641 aaaacgtcat catatctatt tcaagcaaaa gatttagacc ttttgactag tttacctata
    14701 aaagaatcta ctgtactagc aagtaagata ttaatgttgg ttggagcaaa ctatttattt
    14761 tcttcaatat gtatgattat acctgcagtg gtttactttt taaattctga tgtaagtata
    14821 acttatttcc cttatttgat attgctattt ttagctttac cattattacc gatagttgct
    14881 tcatcaataa tttttctatt tatagggcag atatcatcaa gaataaaata caaaaattta
    14941 gtattaatca taggtagcat tatattgatg ttgctttata ccctacttat gtcaagactt
    15001 aattctatgt cagttgaaat gctaaagaat agtgtgtcta tttcagagac aattagaaaa
    15061 gtatatcctc ctatatatta ttttgttgat gctcttaaaa caggaagtat agtttcattt
    15121 ttagcattta tagccatctc aataatacca ttttttatgt ttgtaactct atttgcaaaa
    15181 aaatttaaag atataaatgc taagatgagt gaaggatata agtcaaaaaa ttatgaattt
    15241 aagggtcaaa aaacttcaag accttcaaaa gctttattaa aaaaagaatt taagagatat
    15301 acttcttcgt ttatatactt tttaaattca tctgcaggtt tgttatttct aatggtaggt
    15361 acaattttaa tattattatt tggagcagat aaagtgggtg agttactgaa attgaatata
    15421 gattttaatc ttataaaaat acaattattg ggagtattct tctttataat agtaatgaat
    15481 tgtacaacat actgttcaat ttctcttgaa ggaaaaaact tatggatact gaaatcttct
    15541 ccaatagatg aaagagaaat attctggtca aaaatattga tgaatttttt attgaatgca
    15601 ccactatcta ttttatgtct aatattagta tctataagat tagactttga aattcagttt
    15661 attattgtat caatctgttt gattgtaagt ttttcaatgt ttgtagcatt gatgggatta
    15721 ttatcaaatt tattataccc aaaccttgat tggaaaaatg aggtggctgt agtaaaaaga
    15781 agtgcaagta tgatagttac aatgttagta tcattagctt atgtaattat acttggaggt
    15841 atatatgtat tacttggaat ttcgttttta aatatatata ttattttggc aagtatactt
    15901 actttgatat tagattttat gatatggaga attatttcta ctaaaggagt aagaatattt
    15961 aaaaatttat aggtgtattt atgtcaaata aagacttatc ttttttagtc ttgcaaataa
    16021 taggttaagt agtatactat gtatagtgat atgaaaaaat ttaggagaaa ataaatgaga
    16081 aaattatcca aaagagaaaa agattttatt caatatggat ttttattatt tttgatatgt
    16141 attactactt atttagtatt aactacttta gatataaaac taatacctaa aattataagg
    16201 ctagtaaata agacttatat atttcttggc atattgacaa ttatagtata tatgataatt
    16261 gaatctattg taactcattt gataataaat gcagttcaaa aaacaaaagt aaaatttatt
    16321 ggtattaaaa tggctacaat gggattttac tataacttag ttactccatt tgcatctggg
    16381 agtcaaccaa tgcaaatata tgcacttaca aaatatgatg taagccttag taaatcagtg
    16441 gctatagtta ctaataaaac tgtagtattt caaagtacag ttactgtatt ttgtggaatt
    16501 ttaattttgc taaataagtc attactgatg gagcaagtac attctgtgaa agtcttgata
    16561 acttttggaa tgattatgaa tgtaagtatg ttgttaggtg gactactaat agtatttagt
    16621 ccaaaacaag taaaaatgat agcagaagtt ttgattaatt ttttatctaa atttaaaaca
    16681 tttaaatttt tagattcaaa acgtgataga ataaatcatt atattgatga ttataattat
    16741 tctataaaaa tatttattaa aaatgtaaga atcttagttt taagtatatt acttactgtg
    16801 ttacaattaa tcgcatattt cagtatagtt tattgtgtgt ataaagcctc aaatttaaga
    16861 ggagtttcat atgtacatat aatgacatta caggtctttt tatatatggc tatatcacca
    16921 attccaacac caggaaatgt tggagctaat gaggttacat tttttactat gttctccaat
    16981 ataattccaa aagaattatt ggggtactct gtactcttat atagtgggtt tgtatactat
    17041 tttatattaa tagtttcagg tttatttaca tttggaacgc attatacatt aaattcttgg
    17101 aaaaaggaaa ataaagtaaa ttctaattta gataaggtta ttgaaaaatt aaattaataa
    17161 aataattagg gaaattctat atataaatat ggtgttgaat aagctatatt atattgagat
    17221 atttcccttt tttgattaaa attatagaaa tttgaaataa taagtaataa acagaaaaag
    17281 tgatattgtt ttgaaaggag aaactatgaa acaagataaa caaaatgaaa aacaaagtga
    17341 gatttctaag ataaaacaaa gcaatgataa taaacttgaa atagctcaag aattacatgt
    17401 aagtaaaaat atagggaata tgcttggata tagaatagat aagaaaaaaa tgaatagacc
    17461 aagttaatga aaatgttgaa aatggtacat tttaaaaaat atatataatg aaatgtttta
    17521 ttgttaaatt taaacttatt ttaatggggg aaaaagtcga aaaatatcta aaaagatatg
    17581 gatataaaaa atattaatat atatatacta taaacttgac aaaatcaacc ttttaataac
    17641 tagcaaaaaa tagcaaaatt atataagcgt tatttaattg tcaaaaatga aagctaaatt
    17701 gcatgtccta aaaaaaatga ttgataacat ttatttgtgt gctataatta tatagtaaaa
    17761 caataagtat attgcataat gtatgcaaat cgggaggaga gacggacatg gaagcatcta
    17821 tacacacaat tgccagcaat aatttattga taatttttgc tattgtaagt ataactggaa
    17881 taatttgtag taagcttagt gaaataataa aggttccaga tgtagtgtta tatttacttg
    17941 taggtatttt aataggacca tcatttttaa aatttataga tattcgtgga tttcaaatag
    18001 aaaatcaact aatacttaca tttggttctg catttatttt atatttaggt ggaaaagaaa
    18061 taagtttaaa agtattgaga aatgtgaaga tatctgtatt cttattagct actttaggag
    18121 ttgtgatatc tgcttttata atgcaacaag taataggatt tacttttggg ataagtgcaa
    18181 tgactgcttt actagcagga actataatag catcaacaga cccagccact cttgtaccta
    18241 tatttaatca ggtaaagata aaggataggg taaaacaaac tgtaataagt gaatcagctt
    18301 ttaatgatgc aacaggagct atactaacat cagcagtgtt ggctgtaatt ttgtcaaata
    18361 aattttcatt aggtgaaaat atttatgaac tggggacaat ggttattgtc ggagttttag
    18421 ttggtttaat tacaggaata ctgcttttga aattagttaa tgataaacct tatggaatat
    18481 ttaaagattt tgcaccaata atatctgtta tttcagttgt agttgcatat gaattatcta
    18541 caaaattagg tggaagtgga tatatgtctt gctttattgt aggtataata actggtaaca
    18601 agaaaaattt taaaatttgg ttaagtcaaa aatcttatga tgcagatttt tatgttgctg
    18661 aaactttagg tactatttgt cgtatggcaa tatttataat attgggtagc caagttaatt
    18721 tggctcagtt aagtaaatat tttatgccat ctgtaattac agtattagta ttaatgttta
    18781 tagcaagacc actttgcgtt ttagtttgta cacttgtaga cagggaagca aaatggagta
    18841 aaagtgaaat attatttatg atgtgggtaa gggaaacagg cgtaatacca gcagcacttt
    18901 gtggtattat ttcagcaatg aaagttcctg gatacgaagt gatttcatct gtagtattca
    18961 tgactatact aattacatta gtaatacaag gaagtactac aaaattagta gctaaaaaac
    19021 ttggattatt agaagaagaa gtgataaata taagtgaaaa agtatcaact ttttaaagtt
    19081 ttgctttaaa atagtacctg ttaatggcta ttttaatatt gtctaatgat gattattgaa
    19141 atagtcattt ttttatgtat aagtaattta cagaatttac atattagaca tatttattat
    19201 caaaatttgt tgaagctatg atataattag ttgtatttaa aataagaata gcaaataagg
    19261 gaggaaattt atgtttacgg ttatggatat tgtacagcca gatacagtag aagaagcgta
    19321 ctcaatttta aataaaagaa aaactaacca agtaattggt ggaagtgctt ttttaagaat
    19381 ggggaaaaaa agaataggaa caggaataga attatctaaa ttaaatttag attatataaa
    19441 agagtatgaa gattacgttg agattggttc tatgactact tttagaacat tagaaacaag
    19501 ttccataata aaaaataatt ttggaagaat aatagaagat tcagttaaaa atataatagg
    19561 agttcagttt agaaatgtag taacagttgg tgcaacagta ttttctaaat atggtttttc
    19621 tgacttgata gtagcattac tttcattaga tacggaagta gaattatata atattgggag
    19681 aattagtctt gaagagtttc taaatagaga ttatgagaaa gatttactta ttaagatata
    19741 cataaagaag acaaataaga atgcttctta taaatcaatt agaaatgcaa agagtgatta
    19801 tccaattcta aatgtatctg tatcaaaaca tatggaacaa tttaagttat gtgtaggagc
    19861 aagaccgcag aaagctacga ttgcaaaaca agctagtgaa tttctatcta acaatgaaat
    19921 caatgaaatt aatatagata aagcagtaga aatagcatca gaagaactaa cttttggttc
    19981 taacatgaga gcatctaggg agtatagaaa agctatgagt aaagtacttt taaaaagagc
    20041 tataatggag gttatttaat gttagtaaag attaatataa atgggaagaa aaaaagtgtt
    20101 gatatagaac cagaagaata tctggttgat actttaagaa aagttggtaa tttaagtgtg
    20161 aaaagaggtt gtgacacagg ttgttgtggt ttatgtacag ttttaattga caagaaacct
    20221 acattatctt gtgcaacact gacattgaga gctttagata aagaaataac tacaattgaa
    20281 ggtttagaaa atgaagttaa agaatttagt gaagttttgg taaaagaagg agctgagcaa
    20341 tgtggtttct gttctcctgg ctttatactt actgtacttg caatgaagga tgagcttgaa
    20401 aatcctacag atgatgaaat aaagcattat cttacaggaa atctatgtag atgtacaggg
    20461 tatatgggac agttaagagc tatcaaaact tatctggagg taaaatagaa catgaatata
    20521 gttggaaaag gaatcaagaa aatagatgga atgagtatca caacaggaaa gcctgtatat
    20581 acagatgatt tatcagcaaa agatgctttg gtggtaaaga tacttagaag tcctcacgct
    20641 tatgcaaaaa taaaagatat agatacatca aaggcagaaa tggttgatgg tgttgaatgt
    20701 gttttaacat ataaagatgt accaaaatct cgatttacac ttgctggtca aacatatcca
    20761 gagccatctc catatgatag attaattctt gaagatgttg taagatatgt aggtgacgaa
    20821 gtagctatag tggcagctat agatgaaaaa actgcaatta aagcaatgaa tcttatcaaa
    20881 gtaaagtatg aagtacttac acctgttttg gattttgaag aggcaatagg aaataaaact
    20941 atggtacatg atgaagatag acattgtaac tttgatatag gtatgcaaag agaaaaaaat
    21001 atagtatccc atcatgatta tacaaaaggt gatgtagaaa aagtattaag taattgtgat
    21061 gtagtgattg aagaaactta ttatactcaa gctcaagcac atgcaatgat ggagacgtat
    21121 agggcataca attatttaga ccatatggga agattggttg tagtaagttc aactcaaata
    21181 ccatttcatg taaaaagaca tttatctcgt gcactagaaa taccagctag caaaattagg
    21241 gttataaaac ctagaattgg tggcggattt ggtggtaaac aaactgcatg tgttgagatt
    21301 ttttctgcaa ttgttacttt aaaaacaggg aaaccagcta aaataattta tgatagaaaa
    21361 gaaactttta attgttcaac aagtagacat gcaatgagat taaaagttag actaggtgct
    21421 acaaatgatg gcataataaa ggcaatagat ataaaagcac tttctgatac aggagcatat
    21481 ggagagcatg cttctacaac tattggtttg gttggagaaa aaactttacc aatgtataat
    21541 aaagttgaag caacaagatt tattgcagat gtggtatata ctaataagat gccagcagga
    21601 gcacttagag ggtatggagc atcacaagga tgttttgctg ttgaatcaac tataaatatg
    21661 cttgctaata aattaaaaat ggacccaaca gatttaaggt taaaaaatgt ggtaacagaa
    21721 ggtgaaacta catttgcata tggtaaaact ttaaatagtg tcgatttaat aaaatgtata
    21781 aataaaggca aagaacttat tggatggaat gaaaaatatc cttgtaaaca tcttgataat
    21841 ggaaaaatta gaagtgtggg tatggcaatt actatgcaag gttctggtat acaaggtctt
    21901 gataagtctt cagctgaaat aaaattgaat gactgtggag attatactct tatgataggt
    21961 tctactgata tgggtacagg aagtgataca attttagctc aaatggctgc tgaggttctt
    22021 gatacaagca ttgaaaatat aacagttata tcagctgata ctgacttagt tccatatgac
    22081 ccaggttcat atgcttcaag tactacttat gtaacaggta tggcagtagt taaggcagct
    22141 caagacttaa gagaaaaaat aatttctgct ggagcaacta aactaggtgt tgagaaggat
    22201 gaagtagaat ttgatggtat aaaattaact agtaaaaaag gtagcacttt attattcgat
    22261 atagcagttg attctacaat tggtccagat actaatcaat taataggtct tgcttctcat
    22321 ggtagcccag tatctcctcc accttttata gcaggttttg cagaaactga aattgacaca
    22381 gaaactggaa aagttgattt agtaaattat gtagctgtag tagattgtgg aacggttata
    22441 aataaaaatc tagctaagat acaagttgaa ggtggaattg ttcaagggat tggaatggca
    22501 ttatttgaag aagttagata cacagaaaaa ggaagcatgg acacaaatac atttatgcaa
    22561 tacaagattc cagctagatg tgatattgga aatgttaaag tagattttgt tgaaacttat
    22621 gaaccaactg gaccatttgg tgctaaatct gttggagaag ttgttataaa tacaccttta
    22681 ccagcaatac aagaagctgt gtttaatgga attggtgtaa gaataaatac actccctatt
    22741 acacctgaaa aagtttttat ggaaatgaat aaataattat ttatgaaaat ttagactagt
    22801 tttacatgtt aaacaaccag ttatgtcata cctgttgaaa gatatttaat aagtagttat
    22861 tataatatta tgaattttac ttataaaata caaaattaaa taaggggatg atgttttggc
    22921 tggtaatcta aataatatga gagcagtaaa taattttaga ggagataaga acattttaga
    22981 atgtttagtc agctttgagg gtcgttcaat aagtcagaga aaagtaaggg tattttttaa
    23041 agaaaaacaa aatcaaatag aaattgattt tgcagaagag gaaatttcta aattggttga
    23101 aaatgttgtt ttaaatacat catatcaaga aatgttatat gatgaaatag agaaacaact
    23161 ggaaattgat tgtataggta cttggatgat attatctaaa ttaaaagatg gtagtagagt
    23221 tcactgattt taaaataaat tattagagcc taattttaag gctctttttt gctgttttta
    23281 attaacaata gaaaatttat ctttagtttg tatataattt taatatcata tattctatat
    23341 atataaaatt gaatttgtat gtattatatt gtataatata aaatgaattg ggaaaatagt
    23401 tcgctaaaat aatttgtttt tataaaatta ctgtttaagt ttatagattt tgtataaaat
    23461 aaagttatgt tattaatttt tttaaaaata aaacttttac taggagacag atatgagaaa
    23521 aaatagtatt aatatagcac taactgcagc aattacagca atctatgcag ttttaacatt
    23581 atcattggga tttataagtt atggaccaat acaatttagg gtagcagaga ttatgatgct
    23641 tttggcattt ttagataaag gatatatagt aggtcttaca ttaggttgtt ttttagcaaa
    23701 tgtaatagga ccatatggtg tacctgatat aatttttgga acattagcca catttataag
    23761 tgcaagtatg atttatatta ctagaaagtt aggtaaacaa aataaaagta ctttagttat
    23821 agcttcttta tggccaactg ttataaattc gattgtggtt ggtctaatgt taaatgtatt
    23881 ctttgggctt ccattaattc tatctatgat acaggtaggt tttggagaat ttgtagtagt
    23941 aacaattgta ggagtaccat ttttctgctt tttaatgaaa aaatataaaa atgtcattaa
    24001 tattaaattt taaatagtgt atagtaattt aattaattga gagtattatt agtgaaaaga
    24061 ggtgtttatt tgtcgaaggt aaaaagattg actgatgttt ggatatatat taatgataag
    24121 caaaagttta caataaaaga gttgtcagag gaatttaatc tttcagctaa aacaatacaa
    24181 cgatatttaa aagaattaaa taaaatggga cttccaattc aagcagaaca aggtagaaat
    24241 ggaggttata gggtgctaaa taatagctat atacctcctg ttatatttac agaaaaagaa
    24301 gttatgatta tactatttgc acttaagtca cttcagattt ataattataa gttaatggaa
    24361 atagaaatta attctataat gagaaaagta agttatgaac gtaaaagcag tataaaagta
    24421 ggtatagaaa atattaaaag atacattggc tttgtagcta atgatactaa tgatggagat
    24481 tttaagagta gtaatgtaac tgagtttttt agagcttctt cagaatctct aattttaaat
    24541 attaagtata agtgtggtaa tcagattttg gaaaaaaacg tatgccctat aggtatatat
    24601 ttaaataagg gagcatggtt ttcaccagca tatgattgta aaagtgataa aataatatta
    24661 gttcatatag ataatataat tgatataaaa agaacaggag aaagtaaaaa aatacatata
    24721 aacttggaag aatggttaca tgaagtatat aacaatttat atggaaatag ttcaactact
    24781 aaaaaatttg gtgaaattat ttatctaaat gtattattaa ctaaagaagg tgtttctaaa
    24841 ataaaggaca gttcttggaa tttagatatg gagctaaatg aagatggtag tggaataatt
    24901 agtacattca taaaggttga agatatagat tgttatgctt cgattttatt ttttattgga
    24961 aataatgcta aggttataga gccaaaattt ttgaataagc tactttatga taaggccaat
    25021 gagttaagat atttttatga agaaaatatg gtataatatt tagaaatgtt gaaattaaat
    25081 aattattaag gagatatacg ttataatgga aaattttaat aagaatgcta aaataattgg
    25141 tattggagct gaaggtatta atataataaa tgaagtagaa gaaaaaataa aagcaaatat
    25201 ggatatagaa aaaataaaca taaatcaaga gattgaaaaa gaatatgtta gaagtctttt
    25261 agatggtgta gatatattat ttttgatata ttcatctgaa gataaacata ttagagatat
    25321 tataaaagct gtttcatata tgtcaaacga aagaagagtt ctatctatag gaatggattg
    25381 ttcagagaag gaaaataaag aagatttaga gcttgggaga gagtttaaaa tcaataatga
    25441 tagtatattt aaatttgttg atttaatgaa tatcatggta gagtctattt ctgattcttg
    25501 catgataaat atagatatta ctgatttaaa agaagctatt gtaggagata aaggaattaa
    25561 gtattctttt gaagagtttg aagatacaaa gtcatatagc gagatagctg acattttatt
    25621 tgacaggatg gaatatattg gtgaggaatt tataagtaag aaaggaattg tatttgttga
    25681 aggaagtcca gaattttcta taatggaatt gaatgattta ataagtaata ttcagagcaa
    25741 ggtagaagaa agctatgaag taatattttc tttatatata aaggaaaatt taaatggaaa
    25801 tattagagta ggcttattgt ataattagta tattttagat attaaggaga gtgtatatgt
    25861 ctgaaaatat aagaggtaca gagtattggt taatggaaga atttttttat caggaaacag
    25921 acacaccaca gatttttaga gaagaaagca taattgcact tggatttgat ataaaaataa
    25981 atttaaaaaa agtattcagt atggggaaaa aatcagaaaa gtatattaat gagaattgta
    26041 atgataaaga ttttataaaa aagtttatgt cgattaaaaa aggagattat tttttatata
    26101 aagcatatca aaatatagaa gaaaaagtta aatgtaatgt gtctattggc atagttgaag
    26161 aagattttga aaatggatat gaattaagtc atattttagg gcatacacta ccagtaaaat
    26221 ggatgcataa ttttgataca gtttcaaatt gtaaagtata tacaagtgaa ttttataaat
    26281 taaataataa tgatattagt tcatatttag aaattattaa gtcacaagat aagaaattat
    26341 tgagaaaaag aatagaagaa agtgaaaata ataaatggta tttaaaaaac tattattata
    26401 aaaatgtaga taagtgtgta gatgatgaag aattatttat tcagcccatt aatctagaac
    26461 aattagaaag cctaaaaaat ataaagacag atgattatat tttattgtat aatagcgaga
    26521 aagtaatttg tgaaaatgac catacaatga agagtctatt tggcgtatgt caagttatgg
    26581 aagggttcga taaagagaaa gtaagtgctt tggagggtgg atattttttt cctgttagat
    26641 ggatagagta tgaaaaggag aatatagacg gaaatgcatg ggttatattt gaaaataata
    26701 gtatagttga aaagtatgta aaaagattta ctaataaaat gccattaaat actatacttt
    26761 atggaccacc aggaactggt aaaacataca atacaaaaca gatggtttac aatctagtaa
    26821 gtgaaaccag tctaagaaac agatactata caggttactt agattataaa aataatgtag
    26881 aattttgtac atttcatcaa tcatatggat atgaggaatt tatagagggc cttaagtctg
    26941 atggtgaagg caattttaag ccagaagatg ggatattaaa ggatatatct atagaagcat
    27001 gttataatgc attgaaattt gaaaaaaaga tgagctttga gttggaaaaa gatagcttga
    27061 ctttagaaac tataaaagac aggaaaaaga aattagtatt agaaaatata gaatatagtg
    27121 agagttttaa ttttgaagaa tcagaaaact atgttttaat aatagatgaa attaatagag
    27181 ggaatgtatc taaaatattt ggtgagctaa taacattatt ggaagatgat aaaagactta
    27241 ctaaatcaaa tcaaactatt gtcaaactac catattcaaa ggaaaaattt tctctacctc
    27301 caaatttgta tatagttgga actatgaaca catcagataa atcaatagca cttttagata
    27361 tagctttaag aagaaggttt aattttgaag aaattatgcc agattatgat ttattgtcta
    27421 ttgtagatgg tatagatatt agaaaaatgc tatatacaat caataaaagg atagagtttt
    27481 tatatgatag agaccatgtt attggacaag cttatctact tgctgtagaa aatattaatg
    27541 atatagtagt agtatttaga agtaaaataa taccacttct tcaagagtat ttttattatg
    27601 attcagaaaa agtaggtttg attttaggag gaattggaag aaatgaaaaa gataaataca
    27661 ttgtttataa agaaaaactt atagcttctg agttatttaa aaataataat gcctcaataa
    27721 tggagagtaa agttaactat tgtataaaac aaaacatatc tagtgaggag ctaaaaaata
    27781 tatatgagta aaaatatata tgttaaggaa acctatgaat ggataaggat aggtaatggt
    27841 gaaaatgagc ttacagaaat tgaatatgaa aaattgctta agtatctaga gaacaataat
    27901 gatgtattaa aaagtaatat aatagatatt aaatacaaaa aacttagatt tataaactat
    27961 gtaggcatca tatgttttga aaatgtaata cttgaaatac ttcctaaatt gtcattaagt
    28021 gataatcttg taaaagatag agagatacta ttacagatgc tttctatatg taataaaatt
    28081 ccaattacaa tgaatgaaaa aataagattg agtttgaaaa attataatct cttaaatttt
    28141 tttgttatgt atttcattga gagtatgcaa acacagatga aaaaaggtat ttattttgaa
    28201 tatataaata aaatagagaa cttaaatgtt atgaggggta aaatattatt aagtacatat
    28261 gcaaaagaaa aaggcatttc tccaatgaaa ataagatgtg aatatgatga gtatagtgaa
    28321 aataatttct tgaatcaagt tcttaaaaaa gcatgtatat ctattttatg tagaataaat
    28381 gacaattcaa ttcaaggcaa gattaaaaaa attttaagct attttcaaaa tgtagattta
    28441 atttatatag atagaaaaaa actgttggat tataaatttt ataaaaacaa tgatagattt
    28501 aaagattgtt atttactagc tagacttcta cttttaaatt tgtctatgga taatagtcaa
    28561 aataatcaag aggcattttc tatattattt gaaataaata ctttgtatga agaatatata
    28621 ggaattttaa tcaaaagtat atgggacaat tcatttagag aaacatatat acaagataag
    28681 agtaaatttc ttttgaaaaa tgaacaaact ggtaagaaaa actttaattt aagaccggat
    28741 atagttttat atgacttaaa aaatgaatat gaaattataa ttgacactaa atggaaagct
    28801 attgaagtag attcaaatgt tttttatagg tcaagtgata tataccagat gtatgcatat
    28861 ataacagcat atgaaaatgc aaaaagatgt atattattat atccttgtat tcaaaaagat
    28921 aagaattata gttcctggaa attatcagaa tcatttaagg gtaagtttat agaagcaaaa
    28981 actgtgaggt tagatgatat aaaaaacaca aaaaatgatt taaaaaagat aatttttaat
    29041 tataaatttt aaaaataaga attttaaaat ttataaaagt aattttatat aggtataaaa
    29101 attacgagta gtataaaaaa tttaataaga acttaaatta aaaattttaa aaattatttc
    29161 catataaaat atggcattgt aattgcttat ttaatagagg atttttgtaa aatgaagaaa
    29221 gtatatctat caaattaaaa ctaagtagat atacttttta ttaagttttg ttttaaaata
    29281 atattattaa attataacta agcttttctg ttatgatata attaaataga taatgtgaat
    29341 gattattata tagaatactt atttggagtt gatattttat ggacaaacac agtgattcag
    29401 taatgtatgg tggaatggaa gtatataata tttggggaac aacaacagta gactccataa
    29461 ttggagagtc tgatgtaatg cgtgctctta agaatagaat ttgtaaaatt ggaaatagtg
    29521 attctactgt agctataact ggagaaagtg gcactggaaa agaattaata gcaagagcca
    29581 ttcatctcgc aggaaacaga gggaataaaa cattcgttgc tataaactgt gctgctatac
    29641 cagaaccttt actagaaagt gaactttttg gatatacaaa aggagctttt agtggagcag
    29701 attcaaaagg taaaattggt aagtttgaat tggccaatgg aggggttgta tttttagatg
    29761 agataggaga tatgccaatt caactacaat caaagttatt gagggtatta caggaaaaga
    29821 agtttacgag aataggttca aatgaactaa ttgatataga tgttagaatc atatcagcta
    29881 ctaatagaga tttatttgag ttggttaagg aaaataaatt tagagaagac ttatactata
    29941 gattgaatgt aataccttta gaagtgcctc cacttagaga aagaggagac gatatacaaa
    30001 tattaataaa caattttata gacaaatatt cgagaaagat gaagaaaaac gtgtaccata
    30061 tagagccaga tgtggaacaa atgttgctta agtatccttg gccaggaaat attagagagt
    30121 tggaaaatac tatagaactg gcattaaacc ttcttgagga agatggaata atacataaag
    30181 gaataataaa tagaaagata cttgaatatt ttaagttaaa taatataaat ataaagttac
    30241 ttgaggaaag tgactatgag ataagtatgg aacaagacat acttacactt gaagagtttg
    30301 aaagagccta tataaagaaa gtgttaaagt tttacggaaa tgatactaag tctaaaaaac
    30361 tagctgccaa aaaacttgga atatcactag ctacattgta cagaaaaata gatgtataat
    30421 aattaggctt tttattctca attctaaaat ttgaaattat aaaattgata aaaaacactt
    30481 ggaaaactat tttctaagtg tttttttgtg taatagcatt ttattatcca aaaataaaaa
    30541 aaatttaaaa gaatttaaaa aaataaatgc tttaataaat tatcaaatac taacaaatat
    30601 aataaaaatt atatatgtaa aacaattatg ttaaaaaatt ggcattataa ttgcttcata
    30661 ttaagttgag atgacaaaat aaaaaaagaa aggatgttgt gtgagataat aataactgtc
    30721 attaaaaaat agttgggagt gataaccttg agtaaatatc aaaagaatgt ttctatgttt
    30781 gatattgatg gaaggccacc aattttaaag tgtttgccac tatcaatgca acatatacta
    30841 gcaatgatag ttggaactgt tacagtacct atagtcgtag gaggagctgt gggtgttagc
    30901 cctacacaaa taacactttt agtgcaatat gcattaataa tagctggtat atcaacactt
    30961 atacaactat atccaatagg aaatattggt tcaagattgc ctataatttt tggagttggt
    31021 tttacttatg taccaacact tgtagcagtc ggaggaaatt atggattagc aagcattttg
    31081 ggtgcacaat taataggggg agtggctaca gtattaatag ggatattcat aaaaaagata
    31141 agaaaatttt ttccgaatat agttgcagga acagtggttt ttacaattgg attatctttg
    31201 tatcctatag caataaatta tatggcaggt ggtgtaaata gtcctactta tgcctctatg
    31261 caaaactggg cagtagcggc tataacatta gtggtagtta taggtcttag tcaatttgca
    31321 aaaggatatg caaaattggc agcaatattt ttgggaatta tagttggata ttgtgtatct
    31381 ttagttctgg gtataataaa ttttgaccct attagagagg caacttggtt tgcgatacct
    31441 aaaccgcttg aatttgggat ggaatttgat atgcctgtaa taatctcagt agtaattgta
    31501 agtataatca atgctgttca agcaattgga gatttatcag ctactacaat gggaggcatg
    31561 gataggaata tcacagataa ggaattatca agtggagtaa taggaagtgg aatttgtact
    31621 atgataggag ctttgtttgg aggtttacca ccatcatcat atagccaaaa cgtggggatg
    31681 gtagctatga acaaagtaat aagtagattt gtgcttggaa tagctggtat atttatgtta
    31741 ttgtcggggt ttgtgcctaa atttggtgca ctaatgacta ctataccata ttctgtttta
    31801 ggaggagcta caatatctat atttagtatg ataacaatga caggtataaa gttaattatt
    31861 acagaagagt tgtcatcaag aaatattacc attgttggtt tggcaattgc cttaggcatg
    31921 ggaataacat cagtaccagc agcccaagag gcatttcctt catttgtaaa gttagtattt
    31981 ggagaatctc caatagtaat tgcaacattg gttgcattcg ttttaaatct aataatacca
    32041 aataaaagtc tagaggatga ggctaaagaa agagctgtta tggaagagac taattaagat
    32101 ataataattt aaaagaattg tttaaattat ttagtatgag attgttagat tatttttgat
    32161 agctattcat tttaataaaa aatttaacaa ataaatatat accaggcaat taatgttcat
    32221 ttaagttgaa aatcggggag ggaatattta gaaatttgtt aattttttat aaaaatagct
    32281 cagtttagct gtgtttatcg gttgagcaat aaattcatgg tcataaaaat atttatagaa
    32341 aataattata aaaatattta gtcaagatat ttatgtatgg gaggatttat tttatgaaaa
    32401 cacgtaatac ttcaaaatat gatgtcgatg ggataccacc actaaaggaa tcaatacctt
    32461 tggccttaca acatctgtta gcaatgatag taggaaatat ggtacctgcg atattaatag
    32521 caaacgtggt aggacttaac caggggcaag caacaatgtt gattcagggt tctatgttag
    32581 cagcaggttt agcaacgttt ttacagttat atccaatacc tttatttaaa ggatttaagt
    32641 taggttcaag attacctgta atgatgggaa tgagttatgt atttttagga gcttgtcttt
    32701 cagtagcagc taaagatggt ttagcagctc tatttggagc acagattgct gctggggtaa
    32761 tcgtattctt tgtaggattt ggagttaaga aaattagaca tatattcact ccaatagttt
    32821 ctggaactat aatagcatgt atgggacttg gactattcgc aacagctata aagaatttag
    32881 ctggaggaga aggcacacaa acatttggaa gcccaataaa cttcacagta ggagttatag
    32941 ttgcttttgt aataataatg ataaataaat acggtaaagg tttagtaaaa aattcttcaa
    33001 tattaatagg aatattagta ggttatgcta tatctttagt tttaggattg gttgatttct
    33061 cagccgttca aggagcagct atagtatctt taccaacacc agcagctttt ggattagaat
    33121 ttagaccaga gttaatagta atgtttacta ttatttacat aataggtata gctgatatga
    33181 tgggtgcctg tacaatagct acagtaggag caatggatag agaggtaact gacgaagaat
    33241 tagcatcagt tgttttagga aattctataa cttctataat ttcatcacta tttgcagctc
    33301 ttccaactgg agtatttagc caaaatacag taattgtatc tatgaacaaa gttacaagta
    33361 gatttgtaat agcactaggg gcacttgtat tattactagc agggatatct ccagcattgg
    33421 gtgcaataat gacaactata ccatcttgtg ttgttggtgg agcaacttta gtagttttct
    33481 catcaatagc aatgtctggt ttctctatta tgagtatgga tggattcact gaagaaaaca
    33541 atcttatagc aggtgtatct atagcaacaa gtatgggtct tacaactgct ccacaagttt
    33601 tagaccaatt cccagaaaca attggaactg tccttggagg gtcaagtata gtttctggag
    33661 caataatagc tatattactt caaacattat ttaaattaaa gtcacgtaaa agtgctgaaa
    33721 acgttacttc aaatcttgag gaaaatattg gataaatgta ttagatataa tatgagaaaa
    33781 ccatatggta aaatgttgta atgaaagtat tcaaaggggg atttaagatg attgatatac
    33841 taataaaaaa tgcaataatt gttacagtta ataaagacag agatgttata tttgatggag
    33901 caatagctat tcaaggtgac agaatcttgg acataggaaa tacagttgat attgagccta
    33961 agtatcttga tgctaaaaaa gttatagatg ctaatggaaa agtaatattc cctggcttta
    34021 taaatactca taatcacctg ttccaagtgt tattaaaagg tttaggtgat gatatggcac
    34081 ttcatgagtg gttaaataca atgatgtttc catcagcaaa attcttaaca gaacaagata
    34141 cttatgatgc tgcaatgctt ggatgtatgg aaggtttaaa aagtggtata actacaatgg
    34201 ttgattatat gcatactcac aatagaccag gacttacaga tggaatagta aaggcatata
    34261 aagatttagg tataagaggg gttgtaggta gaggttgtat agatttaggt attcacaaag
    34321 agcttataga agatgtggaa acggttgaaa aagatttgag aagggtattc gaaaaatatc
    34381 ataattcaga aaatggaaga ataaaaatct gtgtagctcc ttcttcaatg tgggctatat
    34441 ctgaagaaat gggtaagatg ctttggaata tagttaaaga atatgattca tattttacag
    34501 ttcatatatc tgaaacagaa tttgcaagaa cagcaacaaa ggatatacat ggagaaatag
    34561 atataaaatt acttgaaaaa tggggtatag taggtccaga agttgtagca gtacattgtg
    34621 tatgtataac tgatgaagac atggaaatgc ttaaaaagta tgacataaaa gtttctcata
    34681 atgtagcaag taacatgtat cttgcttctg gtgttgcacc tgtgccagaa atgttaaaaa
    34741 aaggtataaa tgtgagttta ggtcttgacg gtgcagcaag taataacgca caagatatgg
    34801 tagagcttat gaaattaaca gctttacaac acaaagtaaa taattgtgac cctctggcaa
    34861 tttctgcaga gaaagttctt gaaatggcta caattgaggg agcaagaact cttagaatgg
    34921 aagatgaaat aggttctttg gagattggga aaaaagctga cctagtaata tttaactcaa
    34981 tgctttctcc aaaatcaata cctcttcaca atcctgtatc aactttggta tactcagcta
    35041 gtatgcacaa tgtagagagt gttttagttg atggaaatgt aatacttgaa aatggaaaag
    35101 taactacaat tgaaagtgaa gaacaagtgt tgcttaatgc acaacatgca gcagaagaat
    35161 tatgtaagag agctaatgta actaatagaa tggaaggaca taagtggaat agcttatact
    35221 aatattaaaa taagattgta ataatattct attacaacat tagtttatct gtaggaggag
    35281 aaaatggaaa aaataaaatt aaatattaat gattacatgt atgaaataga agttgaaaag
    35341 aatgaaactc ttttgcatgt acttcgtgaa aaattaaatc taactggagc gaaacaaggt
    35401 tgtaatagtg gcagttgtgg agcatgtaaa gttttgatag atggagttga catgaaatct
    35461 tgtaaacttc ttgcaaaaaa ctgcgaaggt aaagttatat acactataga aagttttgct
    35521 aatggagaaa atcttcatcc aatacaagaa gcttttatag aagtcggagc tgtacaatgt
    35581 ggatattgta ctcctggtat gattataaca acacaagctc ttttaaatag aaatgcatct
    35641 cctaatgaag atgaaattag agaagctttt aaagaaaatc tctgtagatg cacaggatat
    35701 gtaaagatta tagaagctgt aaaattatct gcagctagat tagggggtag ataattatgg
    35761 aaaaggtaat aggaaaatca taccctctaa aagatgcagc tttaaaagtt actggtcaaa
    35821 tgaaatacgt ggctgatatg aaaccacaaa atgtacttta cgctaagatg cttttaagcc
    35881 ctgtagcaca tgcaaaaata aaaagtatag atacaagtga agctgagaaa gtagtaggtg
    35941 ttagagctat agctacttat ctcaatacat cacaaagaaa atacaatggt tcattaagat
    36001 tttatgagca caaaatacct gaaaatgaag ttatattttc agatacagtt agatttgttg
    36061 gtgaccgtgt tgcagcagta gctgcagaga ctccagaaat agcagagaaa gctgtaaaac
    36121 ttataaaagt tgaatatgaa gaattgccag ctgtatttac tatacaagat gcaataaaag
    36181 aagatgctat ctgcatacat ggagattcaa atatagtttc tcaaaacaac ataaatgggg
    36241 gagatgtaga aaaaggcttc aaggaatgtg attatatatt tgaagatgaa tactctactc
    36301 cagcaataca tcatagtgca atagagactc atagtgtaat tgcacactat gattataatg
    36361 ataaattaac tgtacataca ccttgccaaa atacatttgg atttagaata atactatctc
    36421 aaatttttgg gatgtcatta aataaagtaa gagttataag acctgctatt ggaggctcat
    36481 ttggtggaaa attagaactt acaattgaac cagtagcagc cgcattatca aaaatgacaa
    36541 gaagaccagt taaaatggtt cttacaagaa aggaatctat gatatcaaca agaactcgtc
    36601 atgggtcttt tgtaaaatta aaaactggtg taaataaaga tggtgaagta atagcacaag
    36661 acataaaaat atatacaaat acaggagcat atgcatcaag tgctttaaat gttataggag
    36721 cacttagtca taaagtattt aaagtttata aaataccaaa tataaagttt actgggatgc
    36781 ctgtatatac aaatacacca atagcaggag ctatgagagg ctatgggtca cctcaaatat
    36841 ttatggctca acaagctcaa tttgcgaaaa tagcaaagga aataggtatg gatttagtcg
    36901 attttcaaaa taaaaatgca gtagagccag atgatgtcga tataatcttc cacggttctc
    36961 ttggaaatcc tagagtattg gattgtatag agcaaggtaa gaagatgttt aagtgggatg
    37021 aaaagaaaaa acttccaaaa gaagaaggaa aatatttaag aggtataggt atggcaatag
    37081 gtgcacatgg taatggagtt tttggtgcac atagagatgt tgttacattg actcttaaat
    37141 taaatgaaga tggtacgttg acactactaa caggagctca tgatatgggt aatggtgttg
    37201 taactatgca aacaatgatg gtagctgaag ttttaggaat aacacctgat aaagttgata
    37261 catttgaaac tgatacggat gcatgtacat tcaaccttgg tgactatgca agtagagggg
    37321 tatttgtaga aggtggagga gctaaaaaga cagcagagaa attgaaaaat cttatattag
    37381 aagaagcaga aaaattactt gaaacatcaa aagaagattt atatctagac aatggatgtg
    37441 taattagtaa acttgatgaa aatgtaaaag catcactttc tgatgtcgca gtatatagtc
    37501 aaagtaaatc attaagagag ttaactgttg ttgaagatta ttcttcacca gctggacgta
    37561 cttcttatgg tgtacatttt gctgaagttt tagtagataa agaaactaag gatataaaag
    37621 tagttgattt tgtagctgta catgatgttg gtagagttat aaatcctcta aatttagaag
    37681 gacaattaga aggtgggatt catatgggtc taggatacgc attgagtgaa gaattggcat
    37741 ttgatgaaca aggtagacct aaagctactg attttaaaac atataaatta tttagaactg
    37801 tagatatgcc aaaatgtcaa gttgcatttg tagatggtta tgaaaaagct gggccttttg
    37861 gtggtaagag tattggagaa tgtgccgttg taccagttgc gccagctgtt gcaaatgcag
    37921 tatataatgc aactgatgta gagatacatt cattaccaat aaaattaaaa tagtagaaat
    37981 taaagcagaa ataacaattt attgtatttg taaatagata ataaaaatag atttatttgg
    38041 tgaggagata ttattatggc aaagatatta ggtatttgtg gaagtccacg taaaggagca
    38101 acagaatatg cagtgttaga agctttgaaa gaagcagaaa ctatacctgg tatagaaact
    38161 gagtattggt cagttagagg gaaaaaaata agtccttgtg tacattgtga tgcatgtata
    38221 agaaaagaaa ctatgtgtat tataaaagat gatatccaag aattagagca aaaaatattg
    38281 gaggcagatg gaattatagt aggttctcca gtttatgata tgaatataac tgctcaactt
    38341 acagcagtat ttaatagact tcgtccaatg tatttagttc atccaggaaa acttcaaaat
    38401 aaggttggtg cagctataac tactggtgga actagatatg gtggccaaga attgacaaaa
    38461 cttcctataa taaatttctt cctaatgcat gaaatgttag tgtctggagg tttaggtgga
    38521 tgctatatag gtggtacaat atggagtaaa gatggaaaag caaaaggtgc ccaagaggat
    38581 gagacaggta tggacacagt aaaaagactt ggaaaaggtg cagcagaggc agttatggtt
    38641 tctaagtttg gtcttgaaaa atggaatgtc gtaaaagaag aattagatgt taaaaaagat
    38701 gaaaaatcac ctcttagaga ccactaaaga tttattatat tattgaatat atacaaatag
    38761 tgatgtaata gattattgca tcactatttt atgttttaat ttagatttta taaattttat
    38821 attaaaaaat atagaaacaa agtgttttga gatttatttt taaattttaa aaatgagaat
    38881 taaaaagtga gaagatagaa aaggtttttt agttattaaa ttctacatac attgtatgaa
    38941 ctaaagatag aaaagaaaaa ataataaaag cattgcaatt tctatactaa agagtcatgg
    39001 aaaaatatct agtatatatt tagtattggc atgttaattg cttatatatt aaagtataaa
    39061 aatttaacaa taatttggag gtattttaga tgttaaaaga aattaaatgg aaagtaaata
    39121 atttgccaaa gggcgataag gaaaattgta tcaaattttt aaatgaagaa gaaataacta
    39181 aggttagaaa ttttcacaaa agctttcctc aatataaaga aactccatta gcaaacctag
    39241 aaggtttagc aaaaaaatta ggtgttgcag gagtatatgt aaaagatgaa tcttatagat
    39301 ttggattaaa tgcatttaaa gtattaggtg gttcttattc tatgggtaga tacttagctc
    39361 aaagattaga tacagatata tctgagttag ggtatgacaa attgacttcg aaagaaataa
    39421 aagaaaaatt aggagaaata actttcttta cagctacaga tggaaatcac ggtagaggag
    39481 ttgcttggac agctaataaa ttaggtcaaa aatctgttgt attaatgcca aaaggttctt
    39541 ctgaatttag attaaataaa attaaaggag aaggtgcaga tgctagtata acagacttaa
    39601 attatgatga tgcagtaaga ttagctaatg attatgcaga agctgatgac catggagtaa
    39661 tggttcaaga tacagcatgg gacggatatg aagaaatacc agcatggata atgcaaggat
    39721 atggaactat ggctcaagaa gctatagagc aattaaaaga atatggagta gatagaccaa
    39781 cacacgtatt tgttcaagca ggagttggtt cacttgctgg tgcagttcaa gggtatgttg
    39841 cttcaatata tgatgaatgc ccaataacag tagtagtaga ggctgatgaa gctgattgtt
    39901 actataaatc agcagaagct ggagatggaa aaccaagatt tgttggagga gatatgccaa
    39961 ctataatggc agggcttgct tgtggagagc caaatactat aggatttgaa gtattaaaaa
    40021 atcatgcagc agcatttgtt tcagcaccag actgggtttc tgctaaaggt atgagaacat
    40081 taggtaatcc tttaaatggt gatgaaaagg taatttctgg agaatctgga gcagttacaa
    40141 ctggtctttt agtagcagct atggaaagag aagatttagc agatttaaga aaagatttaa
    40201 aattagatga aaattcaaga atacttttaa taagcacaga aggagatact gaccctgaca
    40261 aatatagaag tatagtttgg gatggagaat atccaagtat ataaggaatt actaaaatgc
    40321 aattattaga tattggttta catatttaga agatatataa gttctaaaat ttagaaaata
    40381 tataagtata taaaatacat acattataaa aaatctaggg ggataatgaa atgttaaacg
    40441 aacaaagaaa acaagaagta actgaaatat gccaaaaatt aattcaaaat cctagttctt
    40501 ctggaaatga agaaggtgtt gtaaaagcaa tagaagagtc ttttgaaaaa ttaggttttg
    40561 atagttggtc aagagataga tatggaaata tagtaggatg tataaaaggt aacaagccag
    40621 gtaagaaaat attatttgat ggacatatag atacagttcc agttccagat gcaagtaaat
    40681 ggagtgttcc tccttttgaa ggaaaaatag ttgatggaaa gatatatggt agaggaactt
    40741 ctgacatgaa aggtcaatat actgcaatga tgtctgctgt agcgtatttt gctaaagaca
    40801 ctaatagaga ttttgctgga gaactatatg tagcaggtgt tgttcatgaa gaaatatttg
    40861 aaggtgtttc ggctagagag ataagtaagg ctgttcaacc tgactatgtt gtaataggtg
    40921 agtcttcaga gttaaactta aagattggtc agagaggtag aggagaaata gtagtagaaa
    40981 cttttggtaa accagctcac tctgctaatc cagaaaaagg t
//
LOCUS       DAYAKB010000030        38869 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.030, whole genome shotgun sequence.
ACCESSION   DAYAKB010000030 DAYAKB010000000
VERSION     DAYAKB010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.030"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            787..2367
                     /locus_tag="ACGI3L_001894"
     CDS             787..2367
                     /locus_tag="ACGI3L_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HFG9197603.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            2541..2987
                     /locus_tag="ACGI3L_001895"
     CDS             2541..2987
                     /locus_tag="ACGI3L_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFG9197604.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            3008..4051
                     /locus_tag="ACGI3L_001896"
     CDS             3008..4051
                     /locus_tag="ACGI3L_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFG9197605.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            4822..5982
                     /locus_tag="ACGI3L_001897"
     CDS             4822..5982
                     /locus_tag="ACGI3L_001897"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HFG9197606.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            5984..7114
                     /gene="glgD"
                     /locus_tag="ACGI3L_001898"
     CDS             5984..7114
                     /gene="glgD"
                     /locus_tag="ACGI3L_001898"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HFG9197607.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            7143..8585
                     /gene="glgA"
                     /locus_tag="ACGI3L_001899"
     CDS             7143..8585
                     /gene="glgA"
                     /locus_tag="ACGI3L_001899"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HFG9197608.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            8599..11019
                     /locus_tag="ACGI3L_001900"
     CDS             8599..11019
                     /locus_tag="ACGI3L_001900"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HFG9197609.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRVLL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            11024..12889
                     /locus_tag="ACGI3L_001901"
     CDS             11024..12889
                     /locus_tag="ACGI3L_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFG9197610.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIRIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            13134..13787
                     /locus_tag="ACGI3L_001902"
     CDS             13134..13787
                     /locus_tag="ACGI3L_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9197611.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPMEEMKKEKLL"
     gene            13883..14482
                     /locus_tag="ACGI3L_001903"
     CDS             13883..14482
                     /locus_tag="ACGI3L_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFG9197612.1"
                     /translation="MYPNKEIAIEELEVAGKMNPGPWIKHSYNVANVAKLIAEQCENL
                     NSEKAFVCGLLHDIGRRTGISSVRHIIDGYDYVISKGWDEVARVCLTHSFPVKDIEAD
                     IGNKDISKEQYDFINHYLNNLEYNDYDKLIILCDALADANGFCILEKRFVDTTRRYGI
                     YPFSVERWNKTYEYKEYFEKIINKSIYTLLPNIEKSIYY"
     gene            15072..16547
                     /locus_tag="ACGI3L_001904"
     CDS             15072..16547
                     /locus_tag="ACGI3L_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9197613.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            16634..17047
                     /gene="speD"
                     /locus_tag="ACGI3L_001905"
     CDS             16634..17047
                     /gene="speD"
                     /locus_tag="ACGI3L_001905"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HFG9197614.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            17077..17928
                     /gene="speE"
                     /locus_tag="ACGI3L_001906"
     CDS             17077..17928
                     /gene="speE"
                     /locus_tag="ACGI3L_001906"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HFG9197615.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            17918..18796
                     /gene="speB"
                     /locus_tag="ACGI3L_001907"
     CDS             17918..18796
                     /gene="speB"
                     /locus_tag="ACGI3L_001907"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HFG9197616.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(18976..19176)
                     /locus_tag="ACGI3L_001908"
     CDS             complement(18976..19176)
                     /locus_tag="ACGI3L_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9197617.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            19643..21133
                     /locus_tag="ACGI3L_001909"
     CDS             19643..21133
                     /locus_tag="ACGI3L_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9197618.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            21413..22909
                     /locus_tag="ACGI3L_001910"
     CDS             21413..22909
                     /locus_tag="ACGI3L_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9197619.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            23043..23969
                     /locus_tag="ACGI3L_001911"
     CDS             23043..23969
                     /locus_tag="ACGI3L_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9197620.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            24087..24278
                     /locus_tag="ACGI3L_001912"
     CDS             24087..24278
                     /locus_tag="ACGI3L_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197621.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            24501..24851
                     /locus_tag="ACGI3L_001913"
     CDS             24501..24851
                     /locus_tag="ACGI3L_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6483 family protein"
                     /protein_id="HFG9197622.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            25112..26617
                     /locus_tag="ACGI3L_001914"
     CDS             25112..26617
                     /locus_tag="ACGI3L_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFG9197623.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            27007..28104
                     /gene="dinB"
                     /locus_tag="ACGI3L_001915"
     CDS             27007..28104
                     /gene="dinB"
                     /locus_tag="ACGI3L_001915"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFG9197624.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            28367..29503
                     /locus_tag="ACGI3L_001916"
     CDS             28367..29503
                     /locus_tag="ACGI3L_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197625.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            29496..31043
                     /locus_tag="ACGI3L_001917"
     CDS             29496..31043
                     /locus_tag="ACGI3L_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9197626.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            31378..32244
                     /locus_tag="ACGI3L_001918"
     CDS             31378..32244
                     /locus_tag="ACGI3L_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFG9197627.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            32385..33527
                     /locus_tag="ACGI3L_001919"
     CDS             32385..33527
                     /locus_tag="ACGI3L_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFG9197628.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            33929..35149
                     /locus_tag="ACGI3L_001920"
     CDS             33929..35149
                     /locus_tag="ACGI3L_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6080 domain-containing protein"
                     /protein_id="HFG9197629.1"
                     /translation="MSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDLNNTYDV
                     LLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTDFNSAYG
                     FGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNVERFIYS
                     QFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKIGKMLKH
                     LITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLLYSVFYF
                     PGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIIIFNLTLH
                     GIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIVISNVNG
                     FIEILNIGIKSYPV"
     gene            35178..36065
                     /locus_tag="ACGI3L_001921"
     CDS             35178..36065
                     /locus_tag="ACGI3L_001921"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HFG9197630.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            36099..36728
                     /locus_tag="ACGI3L_001922"
     CDS             36099..36728
                     /locus_tag="ACGI3L_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HFG9197631.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            36760..37197
                     /locus_tag="ACGI3L_001923"
     CDS             36760..37197
                     /locus_tag="ACGI3L_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="COG2426 family protein"
                     /protein_id="HFG9197632.1"
                     /translation="MGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVYVFSVIGSTF
                     VSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGIILFVGIPLPT
                     TGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            37447..38814
                     /locus_tag="ACGI3L_001924"
     CDS             37447..38814
                     /locus_tag="ACGI3L_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9197633.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
BASE COUNT        15327 a         3936 c         6850 g        12756 t
ORIGIN      
        1 cctttgaaaa tattttaaat ggtttttaaa atttggtttt aaaaaatgat tttgatataa
       61 aaaaaccaca cagtatatat aactgtatgg caaaaattcg aataagccac acagtataat
      121 ccatgtggct ctatattatg atgataaaat aaaaacttta acaacaatta ctatagccaa
      181 catagataca atccttaaaa atcataatcc taaggggctt gtatctatgt tatgacaatt
      241 tgtcttaact taggtacaaa ccctaactaa attggctact aaaaaatcgt acttgtttgt
      301 ttaataaagt cttcatattt acctctcctt ttaatttaat aattttgaaa attttgtttt
      361 ctgttttgta tagtaattag tttaatacag taaaaaataa aagtcaacta taaattttga
      421 aaaattatca aattatcaga aaattgagtt taaataaaaa aatttttaca tgtagaatat
      481 agttatattc ttaattattg tttttttata aaaatgaaaa atataaataa gttataaaag
      541 attataaaaa taaagagata tttagataat tagtgtaaat aggttttaaa tcaacataat
      601 aacttaaatt atatggtata ataaattaaa taattgtttt aattcaaaat tttttgttat
      661 tttaaattat ttcaaaactc ttagttttag tgattttatt tatgatattt atgggattaa
      721 aaagatttca atagatattt ttggtaagta tttaagaagt ctttaacttt ataggagtga
      781 taatttatgc taataggtac atctaaatta agcagaaatg ttgatactgc atgtgtagaa
      841 gaagtaggga ttccaatgat tgtattgatg gaaaatgcgg ttatatctgc aatgaaaaat
      901 atggatatag acatgtataa tagttataca gttgtatgtg gtgttggaaa taatggagga
      961 gatggtcttg gaatagcaag acatctaaat acatatggaa aagaagtaaa cgtattttta
     1021 gtaggtaatc ttgaaaaact aagtgaatgc tctaaaataa attacaatgt acttttaaat
     1081 atgggaatta atattataaa tattaataaa aatgatttaa gtgaaaaaaa ttatggagag
     1141 gaaaatgaag tagataaaat tattaaagtt gagaaacaaa atattataaa aaataaaaat
     1201 ttaacaattt ttaaagatag agtatctaaa agtgatgttg tagtagatgc tatatttggg
     1261 actggattaa aacgtgatat aactggtatt tttaaagaag ttattgacat agtaaacgat
     1321 aatagcaaaa atacgtattc tatagatatt ccttcaggta tagatagcga taatggaaat
     1381 gtattaggaa cttgtattag agcaaacaaa acgattagct ttgagtttta taaaagaggt
     1441 tttctaaact atgacactag cgcacttata ggtgatgtag ttgtagaaaa gataggtgtt
     1501 ccagatttta ttacaagaaa ataccatgat gaagagttca taactgataa gacttttgta
     1561 aaaaataata ttagaagaag agataagcat ggttttaaaa gtgattttgg aaaagtatct
     1621 atagttgcag gttcaaaagg attttatggt gcaagtttca tagcaactga atctgctgtt
     1681 aagagtggga gtggacttgt aacattaatt agtagtgaag atgtgcaaga aaaggtatct
     1741 attagactta cagaagcaat gactttaaat tttgaagaag aaagattaaa taaattactt
     1801 aattctagtg atgcaattgg ttttggtcca ggtatgggag ataatagtca aacatttgat
     1861 aaattactta agatagtaga aaattctaat tgcccaatag tattagatgc agatggattg
     1921 aacgttatga aggacagatg ttataagttt ttagaatgga aaaatagatt tgtaattaca
     1981 cctcatttgg gagaaatggc caggttgaca ggagattcaa ttgggtatat aagagaacat
     2041 agagtagatg ttgcaaaaga atttgctcaa aaatataatc tggtggtgct tttaaaaggt
     2101 tatcaaactg tcataacaga tggtaaaaaa acatatataa atcctacagg aaatagctgt
     2161 atggcaactg gtggaatggg tgattgtttg cttggaatga ttacttcatt tataggtcaa
     2221 ggtatggata tattggaagc tacagttagt ggagcatata tacatggcta tataggagat
     2281 aaattgagca aagcaatgta tacggtaaat gctacggatt taataagtaa catttcatta
     2341 acaatgaaag agttgttgga tatataattg gtgatatttg atactacttt gtaacaattt
     2401 taacaaagta tgttgatata atactattaa ttaattaatt tattttattg ttttgtaatt
     2461 taaatttata ttcaaaaaca ttgtataaac atataattta tatagggttt tataattcat
     2521 atgaaaagag ggtagatagt atgaagctaa tatggttgat agtagcagtc ttatttggaa
     2581 tagcagaaat gttaacacca agcttaacat tgatatggtt tagtgtagga gctgtaatac
     2641 ttatattttt aagtagcttt atagagagta ttttcttaca aattttaata tttgcagtaa
     2701 tttctatagc aatgttagtc gtagctacta aaaaaatagt aaaaaaagat aaaggctata
     2761 aatctaacac taatttacaa gcaatgatgt ctaaaaaagg tattgttaca gaagagattt
     2821 ctccaaataa cacaggtcta gttgtagttg aacatgaaac atggacggct atttctatag
     2881 atggtgaaaa gatagaaaaa ggttctacag tagaagtatt aaaaattgaa ggggtaaaat
     2941 tagttgttaa aaaagtagac gccacagtta atgtgacaaa ccaatagaat aaaggaggat
     3001 ttatagtatg ggtactaaaa ttgttttaag tattgtatta atagtagtag tcgtagcaat
     3061 aagtttaact tgtataagag ttataaaaca atctaaagta ggtataataa tgagacttgg
     3121 taagtttcaa aaagtggctg aaacaggtgt acatttctta ataccatttt tagataaaat
     3181 ggcatatgta attgacctta gagaaattgt aatagatttt ccacctcaac cagttataac
     3241 taaagataat gtaactatgc agattgatac agttgtatat tataaagtta cagacccagt
     3301 tagatatgtg tttgagatag ctaatccaat agctgctatt gaaaatttaa cagctacaac
     3361 actaagaaat ataattggtg aacttgattt agatgaaaca ttaacatcaa gagatataat
     3421 aaatgtaaaa atgagaacta ttcttgatga agcaacagat aaatggggta taaaagtaaa
     3481 tagagtagag ttaaaaaata taatgcctcc tcaggatatt caagttgcaa tggaaaaaca
     3541 aatgagagca gaaagagaaa gaagagaggc aatacttcaa gcagaaggta ataagtcagc
     3601 tgcaatactt caagctgaag gtgaaaaaca atctgctata ttaacagcag aagccaaaaa
     3661 agaagctatg gtacgtgtag cagaaggtga aaaagaatct gctatattag tggcagaagg
     3721 tgaagctgaa gctataagac agacagctat tgctaaggca caaggtgaag ctgaaatgat
     3781 aaaaagaact caaatggcaa cagcagaagg tttaaaatta gttttttcag caatgaaaga
     3841 ggctgatata gacaataata ttctagcatt aaaatctatg gaagctcttg aaaaaatggc
     3901 tgaaggtaag tcaacaaaac tggttttacc ttcagaagca gttaatttcc taggaacatt
     3961 caaaggaata aaggaagtta tgagtgatga taacaaagaa gtacttgata taaaagaagt
     4021 tttaaatgat aatgaatcat taaaaaaata aaagagtttt gttatcatag gaaggatatg
     4081 gaaattaaag gtcgaattaa ttaaatatag cacaaaaatg cacgttgaaa agaagaggac
     4141 ttataaattt ttaagtcttc ttctttgttt ttattagaaa gatgaaatta taaaaataaa
     4201 ttaacagaat ttttatacaa tttatccttt actaatgtaa aaagtgttat ataatattat
     4261 ataaaacata tagcaaataa gcatggtttt agttattcta tttatattat taatatatat
     4321 ttataaaaat ataaacatta atactaagaa aactaataaa taatttaaaa gtttatatcc
     4381 ttttgtttaa attatagaca aagaagtatc aattaaaaaa taaagttgat taataattac
     4441 ttgattttcc ttggataatt atttaacaaa tattagatta tattttgcta ttacgaattt
     4501 aacaaattaa aaaataagca tgttcatatg acacaaagga tttataaaaa atgtttttat
     4561 atttataaaa taaaatttgt attatttttt aaccgataat tgaatattaa taaatactat
     4621 agtgcttatg gaaaataatg tatacgtcgg taagtccatt atggggtata cattatatca
     4681 attgtatagt tgatattatt ttatttttat taaggtatta tttaagcaac atttatacac
     4741 gacatttatt gactgataaa gtttataaaa gtaaaaatgc aattataaat attaattact
     4801 agatgagggg agtgtcatta aatgaaaaaa gagatgttag ctatgatttt ggcaggaggg
     4861 caaggttcaa gattaggtgt ttttacaaaa agaattgcca aaccagctgt atcatttgga
     4921 ggtaagtata gaattataga ttttgtgtta agcaattgtt caaactctgg tattgatact
     4981 gtaggtgttt taactcaata tagaccgttg atattaaatt cacatatagg catgggaagt
     5041 cattgggatt tggacagaat aaatggtggt gtctatgttt tacaaccatt tatgaatgaa
     5101 aaagaaggaa attggtataa tggtacagca catgcgatat atcaaaatat ggactttgta
     5161 gatacctata atccagaata tgtattgata ttatctggtg accatatata caagatggat
     5221 tatagcaaaa tgttaaaatt tcataaggaa aaaggctcta aagctacaat agcagtgatt
     5281 gaagttcctt gggatgaagc ttcaagattt gggataatga atacaaatga agattcaagt
     5341 atctatgaat ttgaagaaaa accaagtgaa cctaagagca atttggcatc tatgggagta
     5401 tacatatttg attggaaaat gttgagaaat tattttaagg aagcagaaaa aaatccagaa
     5461 ataaattatg atgattttgg aaaaaattta atacctaaaa tgttagaaga taatgttgga
     5521 atgtatgctt atccatttaa aggatactgg agagatgtag gaactataca aagtctatgg
     5581 gatgctaata tggatataat aaaatctcca gaaacacttg atttagcaga ccctaagtgg
     5641 aagatatata caaatactat ggcaatgcct ccacaatata taggtaaaaa tgcaaatgtt
     5701 catagatcaa tgatagctga tggttgtaga attttaggtg aagtaggtaa ctctgtatta
     5761 tcacatggag ttgttgttgg taaaggaagt aaagtaattg attcagtaat aatgccaaat
     5821 gttgtaatag gtgaaaatgt aactatagaa aaagctatga taggtgagtg tgcaactata
     5881 aatgataatg ttcagataaa gaatgtaaat aatgaaataa atgtagtttc tgagtatgaa
     5941 aatatcgaac ctagatgcgt attaatagaa ggaggtcttt aagatgagaa atgaatgttt
     6001 agggataata aatttaaaca aaaaaggaga cccagcaata aacaaactta actatggaag
     6061 accaatagca tctacaccaa tagctggaag atatagaata atagactttg ctttatctaa
     6121 tatgataaat tcaggaatca ctaaagttgg aatattcgca aaagaaaaat acagatcatt
     6181 aacagaccat ataggtagtg gtaaagattg ggatttaagt agaaaaaaag gtggcctatc
     6241 aatttttagt ccagaaaaca ctaagtatag aaatacttac tcacatagag aaggtgatat
     6301 atatactatc ttagctaatc tagattatat agaaaagagt gaagaagaat atattttaat
     6361 agctccaagc tatatgctat gcaatttaaa ttattctcaa gcattggaat accataaaaa
     6421 atctcataat gatataacta taatatataa aaatgtaaat aatgcaaata aagattttgc
     6481 tggtaactta actctaaatt tagatagtaa caatagggta ataaatgtag gaaataattt
     6541 aggtaagttc cctagagcaa acatatgtat ggagacatat attatgaagc gtgaagattt
     6601 tgttgaatgt atatataaca ttgtaaataa aggcaattat tgttatttag aagaatttat
     6661 tattgaagaa gcagaaaaca tgaaaatagg agcctatgaa tatacaggat atctaaaatg
     6721 tgtaaattct gttgaatcat attttgaaat gagcaaagat ttattaaatt tagaagttgc
     6781 agatgaatta ttatattctg aaagaaagat atttacaaaa gaaaagaatg aatcacctac
     6841 aatttataca gatagtgcta aagtagaaaa tagctttata gcatctggtt gtttaataga
     6901 aggtactgta aaagatagta tcatatttag aaaggtaaat gttgaaaaag gaacagttat
     6961 agagaactca atagtaatgc aaaattgtgt aataaagtca aatgcaaaac tatataatgc
     7021 aatattagat aaaaatacaa gtgtatcaaa tgggaaagaa ttaagaggag atgaaaaata
     7081 tcctcttgta gtggaaaaga atacaaatat ataaataaat tttttagaag ggggaatgac
     7141 taatgaaggt tttttatgta acagcagagt gttggccctt tgcaaaaact ggaggattag
     7201 gagatgtttc ttatgcattg cctaaagaat taaaaaaaga aggtgtagat gtaagggtaa
     7261 taatgcccaa atattcaact ataccaagtt atttaaaaga tcaactaaaa gaaatagctg
     7321 tgtttagtgt acgtgttgga tggagaaatc aatactgtgg tcttttagaa atggaattgg
     7381 atggtgtaaa attttacttt atagataatg aattttattt tagaagagaa gatgaaagaa
     7441 agagtatcta tggatatgga gatgatgcag aaagatatac tttctttaca gatgcagttt
     7501 tagaagctat aagtagaatt gatttttatc cagatgtaat acatataaat gattggcata
     7561 cagggatgtt accattaatt ctaaaagaaa gatatgcaac ccttgagggg tataaaaata
     7621 taaaaactat gtatactata cataatctcc aatatcaagg tgtatttgat aagcatgttt
     7681 tatatgatat attggactta ccacaaaaat actttgataa tggagatata gagtattatg
     7741 gctcaataaa ttttatgaaa gctggtataa attttgcaga taaaattata actgttagtc
     7801 ctacttatgc aaatgaaata caaacatctt tttatggcga acaattagat ggattactta
     7861 gaaaagagtc aggaaaatta aaaggtatat taaatggtat agattatgat ttaaatgacc
     7921 ctgcaaaaga taaagatata tttgttcatt atgatgtaga ctcaattgac aaaaaagtag
     7981 aaaataaatt gagattacaa gatatattgg gactaaaaaa agattcatct attccgttga
     8041 taggtatagt ttcgagatta gtttctcaaa aaggatttga tttaatagca tacatgatgc
     8101 cagaacttat gagagaagat ttacagattg tcgttttagg aactggagaa catcaatatc
     8161 aatcaatgtt caactattac gattctaatt tttcagataa agtatcagct agaattactt
     8221 ttaatgcatc attggctcaa cagatatatg ctgcaagtga tatgttctta atgccatcat
     8281 tatttgagcc ttgtggtata ggtcaaatgt tagctatgag atatggttct ttaccaatag
     8341 ttagagagac tggagggctt agagatacag taacacctta taataaattt actggagaag
     8401 gcaatggatt tagttttaaa aattacaatg ctcatgagat gtttttctgt ttgaaaaatg
     8461 caatcaaagt atttaaggac aaagaaaaat ggattaaatt agttgaaaat gcaatgaaaa
     8521 cagataatag ttggaaaaaa tcagctaagg agtatataga aacatataga gacatatgtg
     8581 attaaaggag tggttttttt ggtaacaata agcaaaaaga aattcaagca aaaatttgaa
     8641 gtaaaaatgt atagcttata tgcacaatct atcaaggaag ctactgatga acaattgtta
     8701 aatgtattat gtagtctatt gaaagatgag atagcaaaaa aatgggttgc tacaaagtta
     8761 gataagaaaa aagaagttta ttattttagt ttagaatttt taatagggag acagttaaaa
     8821 tctaatttat taaatttaaa tattgaagaa gaagttagag aaggtttatc tgaattagga
     8881 atcaacttgg atgatttaat tgaagctgaa gtagacccag ccttaggaaa tggtggactt
     8941 ggtagattag cagcttgctt tttagattct atggcatctt tgaacataag tggtcaagga
     9001 tatggaataa ggtataaata tggtctgttt gaacaaaaat ttgtaaatgg ttatcaggta
     9061 gaagtgcctg ataactggct tacagaagga cgatatgcat gggaaactgt aagaccaaat
     9121 gaagcaacaa tggtgaagtt tggtggtgag gtagaattaa tcaaggaagg tagtcattta
     9181 aaagtaattc ataaaaacta ccttcctgta atggcaatgc cttatgatat accaataatc
     9241 ggataccaaa accaatgtat aaatacttta agattgttta agagtgaaat accaaagaga
     9301 gattttggtg aacttacctc aaatgctcta aattattctg gtagctatga agaggcttta
     9361 aaacataagt attatactga ggaaatatca caggtattat atcctgatga ttcaaactat
     9421 gcaggtaagt tgttgaggtt gaaacaagaa tacttttttg taagtgcagg gatacaagat
     9481 ataataagaa aatataaaaa gaacaaatta aatattaata atttattcga taaggtagca
     9541 attcatataa atgatacaca tcctacctta tgcataccag aacttatgag agttttgctt
     9601 gatgaagaaa atttatcttg ggatgaagca tgggaaataa ctaaaaaaac agtgtcctat
     9661 actaatcata ctataatgtc agaagcaatg gaaaaatggc ctgtaagtat gatgaaagaa
     9721 ctattaccaa gaatttatat gataatagaa gaaataaata gaagatatgt agaggaatta
     9781 aataataaag gatatgacca agatagaata aaaagaatga gtataataga ctgtgacaat
     9841 atcaatatgg caaacttatg tattgtcaca agtcatagtg taaatggagt tgctaagctt
     9901 catactcata ttcttgaaac agaggtatta aaagatttct atcaagatga accaaataaa
     9961 tttaataata agactaatgg aattgcacat aggcgatggc ttataagttc aaatcctcaa
    10021 cttagcaatt taattacaga tttaattggt gattcatgga agaaagatac attacaatta
    10081 aaaaatattg aaaaatttaa aaatgattcc tctgttttac aaagacttga tgatataaaa
    10141 tacaataata aagcaaatct agcaaagttt ataaaagata aatacgattt aaatgtagac
    10201 ccaagttcga tatttgatgt tcaagttaag agattgcatg cgtataaaag acagttactg
    10261 aatatattta atgtacttca tatgtatcat gaattacttg ataatcctaa tttgaatctt
    10321 gacccaagaa cttttatatt tggcgcaaaa gcagcaccag gatattattt ggctaaatgt
    10381 ataattaaat ttataaattc tgttgcaagt actataaata atgatgttag agtaaaggac
    10441 aagttaaaag tagtattttt agagaattat ggagtatcat tagcagaaat aataatacca
    10501 gcagcaaatg ttagtgagca aatttcaact acaactaagg aagcatctgg aacaagtaat
    10561 atgaagttta tgatgaatgg tgctataact ttggctacac ttgacggtgc aaatgtagag
    10621 atatgtgaac aggttggtaa agaaaatatg tttttatttg gacttagtgc agaacaagta
    10681 ctaaattata ataaatatgg tggatattct tcacttgacc tatatcattc taatatggat
    10741 ataaaaaggg tagtagatga tttaataaat ggatttattc ctaatcttgg cgaagaagga
    10801 agaagtattt ataattcact cactacttac aatgatgagt attttgtatt gagagatttt
    10861 gaaaattatg gtcaagctca agcagatata aacaggttat atagagataa agaaaaatgg
    10921 aataaaatgt ctttagttaa tatagctaat tctggatttt tttcttctga tagaacaatt
    10981 tctgagtatg caaaagacat ttggtttaaa agggtgtgat taaatgcaaa gtgtaataga
    11041 atataactct tgggataaaa attttaaggc tccgtttgga gctttaaaat ttgatgagga
    11101 attgaccatt tgtgttaaag taaatgaggg atacaatatc aagtctattt ccctagaaat
    11161 aaatagagaa gaagaaatga gaacaataac tttaaatgaa gaattagata atgataaact
    11221 tggaaagtgc ttttgtggta agattgaaaa gtttgatggt acaggtgttt atttttatta
    11281 ctttaaagtt gatgttgaaa tggatggtca gataaagact ttattttatg gaaaaaacag
    11341 agataatgga tattcttgtg aatataatta tagtgatatt aataaatatc aaatcactgt
    11401 ttacaaagat tttaaagtac caacatggta caaagaagga atactttatc atatatttgt
    11461 agatagattc aataatggaa atcgtagtgg taaggttgat aatcctaaaa aaaatagttt
    11521 catatatgga aattgggaag atacacctat gtacataaag gatagtcaag gggatgttat
    11581 aagatgggat ttccatggtg gaaatttaag agggataatc aataaacttg gatatttaaa
    11641 aaaattaggt gtaagtatac tatatctaag ccctatattt gaagcctcta gtaatcataa
    11701 gtatgataca ggtgactata aaaaaattga cccaatgttt ggggatgaag atacatttaa
    11761 agaacttatt gataaagcaa aagaaaaagg tatatcaata gtattagatg gagtttttag
    11821 tcatactgga gcagatagta aatattttaa tatgtatgga aactataata gtttaggggc
    11881 atatcaatct aaagaatctc catattattc atggtatatg tttgaagaat ttcctcaaaa
    11941 atataaaagt tggtgggatg ttaagacatt gccaaatata aatgaattag aacatagcta
    12001 tatggattat ataatatatg acaatgatag cgttataaat aaatgggtaa atatgggtat
    12061 taagggctgg agactagatg ttgcagacga attaccaact aagtttataa gagagttaaa
    12121 aaaggaatta aaaaaggcag atgatgactc aattcttata ggtgaagtat gggaagatgc
    12181 atcaaataag attagctatg gtcagagaag aagttattta ttaggtgaag aattagattc
    12241 tgttatgggt tatcctttta gaaataacat gttttctttc ttaaaaggag aaattaattc
    12301 atatgaactt tgtaatagat atatgcagat taaagaaaat tatccaaaag aatcatttag
    12361 gtctaattta aatttaattg gaacacatga tgttacaaga gctaaaacgg aattaaatga
    12421 tgatgtagat ttagtgaagc ttgctgtagc tatacagatg acatttgaag gagtaccata
    12481 tatatattat ggagatgaag caggtctttg tggaggtgtt gacccagata atagaagaac
    12541 ttatccatgg aaaaatgaag acgaagatat gcttaatttt tatagagatg ttataagaat
    12601 tagaaataag aataaacttt taagttctgg aaatacagaa tttatatata ctaataatga
    12661 ttctgtattt tcttttatta gagttaatga aaataatgat agaatgttaa ttttagtaaa
    12721 tagaagtgaa aatgtggaaa gtatatcatt atgtatagag agtagtttta ttgaggaaat
    12781 acctataaag tatagtctta aaaatgcaaa tagtactata caaattgaaa ataatgagtt
    12841 gaaagtagat ttagactcta aatcatttag aatttttaga gtaaattaaa tatctttttt
    12901 tagaaaaata aatagaaaat aaggtgaatg tggaaagagt tttgttttat caaaactttt
    12961 tctacttttt ttgtataaat tatcataaga attttagtat ttcaaaatat tacaaagaag
    13021 tataaaaaat atcataattg tgatattata taaattagta agataaaact gaactctcta
    13081 ccaaagttgt agggagattt aacttttata atcttaatat ggaggaacgt cttatgaagg
    13141 tagatccact tacaactcaa gtatatgact atatatcaaa gaaaatccaa aatggagaat
    13201 atgaagctaa tcagagaatt actgaatctg agatttgtaa atctatcgga gttagtagaa
    13261 caccagcgag agaagcatta actaggttag caggtgaaaa tttactagaa aaaataccta
    13321 ataagggatt tgtagtaaaa gaatttcagg aaaaggagaa attagacacc tattccgtaa
    13381 ttggagtatt ggatgcgtta gccggttctt cagcattaca aaatttaact gaatcagacc
    13441 tagtaaaaat ggaagaatta acagaaatga tggcggtctc tataaagtat aaaaattaca
    13501 atagctattt aaaattaagt aatgaatttc acgatatata cataactaaa tcagataatc
    13561 aggtgttagt aaatctattg aactctttaa gatataattt tatgtcaaag tcatatacta
    13621 gtgataatga agatgagtta tataaaatgt tgacatacag caataatcaa catattgaag
    13681 tagtaaaatc tatgagggag aatgatttag aaaatgttga aagaattttg agagaacatt
    13741 ggaaaacgat acctatggaa gagatgaaaa aagagaagct tttataaagt ttctctttat
    13801 tttttatacc attttatcac tatttttttg aattattaag tagaaaataa taattaattt
    13861 aaacttgagg aggaaaacta atatgtatcc aaataaagaa attgcaatag aagagttaga
    13921 agtggctggc aaaatgaatc ccggtccatg gataaaacat tcttacaatg ttgctaatgt
    13981 agctaaattg attgcagagc aatgtgaaaa tttgaatagt gaaaaggcct ttgtatgtgg
    14041 attattacat gacattggaa gaagaactgg tatttcttct gtaaggcata ttattgatgg
    14101 atatgattat gttatttcta agggatggga tgaagtggcg agggtatgtt tgacacattc
    14161 ttttcctgtt aaggatatag aagctgatat tggaaataaa gatattagta aagaacagta
    14221 tgattttatc aatcactatt taaacaacct tgaatataac gattatgata agttgattat
    14281 tctttgtgat gcattagcag atgcaaatgg gttttgtatt ttagaaaaaa gatttgttga
    14341 tacaacacga agatatggaa tatatccatt ttcagttgaa cgatggaata agacttatga
    14401 gtataaagaa tatttcgaga aaataatcaa caagtctata tatacattgt tacccaatat
    14461 tgaaaaatct atatattatt aaatcctaag ttaataattt aatatccagt atcaccagca
    14521 gttggtcatt atgattgact gcttttatta tgcttatatt aaaaaaatac actatggttt
    14581 gtgtatatca aagttatatg gaatgaaaag agaatttatt ttatcaatta aaaaatttaa
    14641 taaattttat attaaaatta aaatacaaaa ataggaaaat tatttagtcc aactaaacca
    14701 agaattttga tatgtgaaat aagaataata taaaagttta gtaataaaat acttataaat
    14761 taaaaatagt aaactcaaaa gcttactaaa actcaaaaaa gtaaaaaaaa caaaataata
    14821 aaaaataaga aagtttataa atactaagtt ttaaaaaaat taatataaac aacaaaaaaa
    14881 taaaaagttt ataaatattg atatagctaa tgtatatgtt tttgagtaac ttcaaaaaaa
    14941 cacttgtaaa aatgctgaga tgttaatata ataaatatca tgagtttaat aaaagtaaaa
    15001 ataaaaaata gaaataataa ataataaata ttaaaaatat ttgaatatag agaggagatg
    15061 aatttgaaat catggatagc gagtttgcaa atgcagttga attaagctat gagtgtgctc
    15121 cattattaga gtcgttaaag gaatactcag agaaagatat agcttgtttt gatgtgcctg
    15181 gacatgtaaa aaatagaggt gtagctatat taaataaata tctaggtgaa agtctcatga
    15241 aaatggatat aaattcatca ccaactatgg ataatgtatc tgcgccaaat gggattataa
    15301 aaaatgcaca agatttgcta gcacaagcat atatggctga tgaggcattc tttataacga
    15361 atggcacaac tcaagcaata catgcaatga ttttgagtgt tataaaacca ggtgaaaaag
    15421 tattacttcc aagaaatata cataaatcag taataaatgc gttaatactt tgtggaggaa
    15481 taccaatatt tatacaacca gaatttgatg aaaaactagg tataagttta aatattactc
    15541 ttgaaaaagt tagaacagag atagaaaaag attgtaatat aaaagcatta tttttcctta
    15601 atccaactta ctatggagtt tgtgcagacc ttgagagtat tatagaacta tgccataaaa
    15661 ataatgtttt agtgttagtt gatgaagctc atggtgcaca ttttccattt catttagatt
    15721 tacctccttc tgcaataagt ttgggagctg atatggtagc tgtaagtata cataaaactg
    15781 gaggagcatt gacacaatct tcagcactct tattgaatag agataatgta agttttgaaa
    15841 aggttcttca atcaatcaat atgctacaat caacatcagc atcttatttg cttatggcaa
    15901 gtatagatgg tgctagagtt aatctagttg agaatggtga aaagcaactg tcaaaagcat
    15961 taaatctatc taggtatgca aaatctaaat taaacaaaat tgatggaata aaagttttat
    16021 ctacagaaat attgaaacaa aaaggtgtta aatttataga tgaaacaaaa ttgtgtataa
    16081 atgtaaaaga attaaatttg actggatttg aagtatacga tttattatat aaaaattttt
    16141 caattcaagt agaattggga gattcatata atatactggc acttgtgtcc attggaacaa
    16201 ataaatcaga tatagataga ttagtaaaag cactttctat aattgcaaag atttatagaa
    16261 aagaatcaac attaaatgaa tttaatatgg ttcaaataaa tccaattatt aaacttaatc
    16321 caagagaagc tttttatgca ccaaaggaaa gtgtagaaat caattcatgt atagatagaa
    16381 tttgtggaga atcaataatg gcatatccac caggtatacc gattattgct ccaggagaat
    16441 tgataacaga agaaattatg gagtatatta ttttcttaaa aaatagcaat gcatatctta
    16501 cagatgtaca agataaaaac ttagatagaa tattagtaat aaaataaatt actttatttt
    16561 gcaagggcaa gtatttgtta agtagagttt atcaaataga acttattaaa agtataaagg
    16621 agttggggtt gaaatgaaat ttgaaacact aggaagacat atactagtag aatactataa
    16681 ttgtgatgaa aacgtactta aagacccacg tcttatagaa aattttatga atgattcagc
    16741 attaaatgca aaagcgacaa ttgtggattc tgtattccac cattttaatc cttggggggt
    16801 ttcaggagct gttataattg ctgaatctca tttgacaata catacatggc ctgaatatgg
    16861 ctatgcagca gcagattttt ttacttgtgg tgatatagac ccatggaaaa gttttgaatt
    16921 attagagcaa cttttaaagt ctgaaagaag cgagtctaca gaaattccaa gaggcttaac
    16981 tacaaaaatt aaaaaatatt caaaaaaaga tttaggtaag attactcata aaccagaagc
    17041 agtataaaac atacaagaga aagtgaggat tattatatgg aactttggta tacagaagaa
    17101 tggacagaaa atgtaagatt ttctataaaa gtaaataaac atctatttga aggaaagtct
    17161 caatttcaaa ggatagatgt gtttgatagt gatgaatttg gaaaatttct aacaatagat
    17221 ggattaatga tggtaacata taaagatgaa tttatatacc atgagatgat aactcatgtt
    17281 cctatggcta caaatttaaa cataaagaaa gtattagtca taggtggagg tgatggaggt
    17341 acagtaagag aattaagccg ttatcctcaa atagaaaaga ttgacatggt tgaaatagat
    17401 aaaatggttg tagatgtatc taaggagtat atggatatat gctcatgtaa attagatgat
    17461 aaaagagtga gtttatattt tgaagatggt gttaattttg ttaagtgtgc acatgataaa
    17521 tcatatgacc tgataatagt agattcaact gacccaatag gaccaggtga agggcttttc
    17581 tcaactgatt tttataagga ttgttataga atactgactg atgatggaat tttagtaaat
    17641 caaagtgaaa gtccgtattt tgactttaat gctaaagaga tgaaaagagc taataaaaaa
    17701 ttaaaacaga tatttccaat atcagaagtt tatcaagcac atataccaac atatccatct
    17761 ggtcactggt tgtttggatt tgcttcaaaa aaacttaatc cagtaaaaaa tcaagataga
    17821 aatggatggg agaaattaag tttaaaaact aaatattata atagtgatat acatttaggt
    17881 tcgtttatgt tacctcaata cgtgaaggag atgctagatg aagaataatt tctatcatat
    17941 gaacactttt atgagtatgg acaaaaatta tgaagaatct aatcttatag tatttggtgt
    18001 tggatttgat ggaactactt ctaacagacc tggggctaga tttgcaagta gctctatgag
    18061 aaaagaattt tacggtcttg agacatatag tcctttttta gatttggatt tagaggatta
    18121 taatatatgt gattatggag atttagaaat tagtgttgga agtacagaac aagtcttaaa
    18181 agaaatctat caagagacat ataagattgt tagagattca aaggtaccct ttatgattgg
    18241 aggagagcat ttagttacat taccagcctt taaagcagta catgaaaagt acaatgatat
    18301 atatgtaatt cattttgatg cccatactga tttgagggaa gaatataata atagtaaaaa
    18361 ttctcatgca acagtaatta aaagaatatg ggatattgta ggtgataata aaatatttca
    18421 atttggtata aggtctggga caaaagaaga atttaaattt gctacagaag aaaaacacac
    18481 atacatggaa ataggaggaa tagatacgtt tgaaaatata gttaatatgc taaatggaaa
    18541 gaatatttat ctaactatag atttagatgt attggatgca tctgtgtttc caggaacagg
    18601 tacaccagaa cctggtggtg taaattatag agagtttcaa gagattttta agattataaa
    18661 aaactctaat ataaatatag ttggttgtga cattgtagag ttaagccctg attacgatac
    18721 aacaggtgta tcgacagtta tagcttgtaa aatcttaaga gagttatgct taataatatc
    18781 tgataaaatt aaatagagta ttttatataa atagtatata ttataatata agaagttatt
    18841 ttaaaaaagt tagtttaagt ttgacgcttt tctaaagtaa cttcttattt ttgtaattaa
    18901 aaataaatat aataaacaac aaaaaagagc cctcgatagc tccttttcta aaatatatat
    18961 atttaaatta aataattata ttctatttac gttttcagct tgaggtcctc tattaccttg
    19021 agttatatca aagctaacct tttcgccttc ttctaaagtt ttgtatccat cattttgtat
    19081 agctgagaaa tgtacgaaaa catcatcttc tccctctaca gatatgaacc caaatccttt
    19141 ttcattgtta aaccatttta ctattccgtt tttcattata agaaaacctc cgcattatta
    19201 aaaaatacaa actaaaaaaa taagtctgtt ctattaatat aacataaatt ttaaataaaa
    19261 gcaaataaaa tttttaaaaa aattaattac ttttagaatt taataaaaat tgttaaatta
    19321 tacagtgaga agtattgtaa aatttgacga aaatgtaaat gtagataata aatttaatat
    19381 caaaaaatgt aacaaaaagg tatgtaagta aaaagtaaaa ttaaaatata taataaaaaa
    19441 tattatatat tagattgaaa agtaaaaata aaaatagtga aatttcagaa atatcaataa
    19501 tattatataa taaaacaaaa aaacactata tatattcgat aaaataaaat ttaaacatat
    19561 aatattttat gtatatatta ataaaaggac atattgtgtt ataatggtat cgtataaaat
    19621 catttacggg ggtggtatta aaatgtttca atttgaaaca caaatacaca aattaagaca
    19681 tgatgtttta actgcaatag ctagacttgg aaaagaagat aaccttacca gagaagcaat
    19741 ggataatatt cagtatgaaa taataaaagg tgagaaacct acatacagat gttgtgttta
    19801 taaagaaaga gctataatat ctgagagagt aaatgtaagt atggggttac aaccaggtca
    19861 agataagata gatttagata caatggatat agaagaagat gaacaaatta tatatatttt
    19921 ggaagctgca tgtgacagtt gtccaataaa tgaatttaca gtaacagata tttgtagagg
    19981 atgtctagca catagatgta aagaagcttg taaatttgga gctataacac atgtcggagg
    20041 aatggcctat ataaatcatg aattatgtaa ggcttgtgga atgtgtaaaa aagcttgtca
    20101 atatgatgcc atctcagagg ttgttagacc atgtaagagt gtttgtccaa ctaatgcctt
    20161 aggatttgat agagaaaata tgaaagctat gatacatgag gataaatgtt taaactgtgg
    20221 agcatgtatg tcagcatgtc catttggagc aatatctgat aagagtttga tagctcctgt
    20281 agctagaaag ttagttcaaa aagagaaaat gtatgcggtg gtagctccag ctataacagg
    20341 tcaagttgaa gcaaatgtta catatggtca aataaaaaat gctataaaat cactaggatt
    20401 tgttgatgta ttagaagcag cttgtggagc agatgcagtt acagttcatg aaagcttaga
    20461 atttgctgaa agaatggaaa agggagaagc ttttatgaca aattcttgtt gtccaggatt
    20521 tgttggttat atagaaaaaa catacccaaa tcatgtaggg aaaatatctt ctacagtatc
    20581 tcctatgata gctagtggta gatttataaa aagtcatgaa ccagatgcta aagttgtatt
    20641 cataggacca tgtacagcca aaaagagtga ggcagctaag aaagaattaa aaggagctgt
    20701 tgattatgta cttacttttg aagaaataat ggcattattt gaggcatttg atatagactt
    20761 ggctaagtgt tcaaatgaag atatagatga tgcatcaatt tttggaagag gttttggagc
    20821 tgctggtggt cttacaaaag ctatagaaaa ttatcttgct gaaaaaggta ttggtgttaa
    20881 ttttgaacct gtaaagattt ctggttcaag agaaatcaag aaaactatga ctatggctaa
    20941 tttaggaaag ctagaaggta attttataga aggaatgatg tgtgaaggtg gttgtataaa
    21001 tggttctggt aaattcttat caggtgcaaa ggttaaagcc acttttgata gaaaaaattc
    21061 tcaatcaact aagaaaagtg tcttagcaaa tacaaagata aaagatttta gtaatataaa
    21121 tttagaaaaa taaagataat acaaagcaac aaaaatacat attgttaata gagttgttct
    21181 aagttgaggt ttaacttttg gacaactcta tttttattta tatatttaat tattgaacaa
    21241 ctaaaataaa aattatatac acttaaaata aaaattacat atataatatt ttgtatataa
    21301 cttaacaaag tatatgccta tgttataata atttatagaa ataaataaaa aatacaatat
    21361 acataatagt agaaatatag caaaaaggtg tgatttatag ggaggattac ttatgtttga
    21421 atttgaaacg caactaaaaa ggttaaaaca tgaagtttta acagcagtag caagactatc
    21481 tattgaagaa aatttaacaa aagaaaatat agaaaaaatt ccatatgaaa taattaaagg
    21541 agaaaaggcg agatatagat gttgtgttta taaagagaga gaagtagttc ttgaaagggc
    21601 gcaacttgca ttaagtttaa ctccaaatag taaatatgga gatataaatc cagattcagt
    21661 tagtttggac acagatgagc aaattatata tatagttgaa gcagcatgtg atagatgtcc
    21721 aataaatgaa tttacagtta cagagctttg tagagggtgt ttggctcata gatgtaagga
    21781 agcatgtaaa tttggggcaa tttcttatat aaatgggaga gcatatataa atcatgattt
    21841 atgtaaggct tgtggaatgt gcaaaagttc atgtcaatat gatgctatat cagaagttgt
    21901 aagaccttgt aaaagcgttt gtccaacagg agctttggat tttaatagaa acactatgaa
    21961 agcaatgata catgaagata attgtataaa ttgtggagca tgtatgtcag catgtccttt
    22021 tggagcaata tctgataaga gtttgatagc acctgttgca aaaaaacttg caaagaaaga
    22081 aaatatgtat gcaatagtag ctccagctat aacaggtcaa atagatagta atattacata
    22141 tggtcagtta aaaaatgcta taaaatcact gggatttgta gatatgatag aagcttcttg
    22201 tggagcagat gcagttacag ttcatgaaag caatgaactt attgaaagaa taaaatcagg
    22261 agataattac atgacaaatt catgttgtcc gggatttttt aagtatatag agaagatgtt
    22321 cccagatgaa aaagatagaa tatcatctac agtgtctcct atggtagcaa caggaagatt
    22381 agtaaaaaaa atagattctg atgctaaagt tgtatttata ggtccatgta cagctaaaaa
    22441 gagtgaggca acagagaaaa gtttaaaaga ttcagtagat tatgtactta cttttgaaga
    22501 actaatggca ttatttgaag catttaatat agatttatca aaatgttcaa atgaagatat
    22561 aaatgatggt tcgatttttg gaaggggatt tggagcatct ggtggacttg ccaaatcagt
    22621 acagaactat attgctgaaa aggggcttag ttttgatttt gaacctataa aagtatctgg
    22681 tccaagacaa attaaaaaga caatgacaat ggctaaattg ggaagattag aaggtaattt
    22741 tatagaagga atgatgtgtg aagaaggttg tattaatgga gccggtaagt ttttatcagg
    22801 tgtaaaagcc aaaaatactt ttgatagaaa aaatggacaa tctactaaaa agagtgtttt
    22861 atctaatgat aagattaaag aatttgaaga tgtaaattta gaaagataat tgttttggta
    22921 cagtcatttt tttattatgc cacaaatatg cctaaaattt gcccttttta tatgtgtatt
    22981 ttacagagtt aaggttgcta tactataaat atgtaataaa taaaatttat aggagctttt
    23041 ggatgaggaa aatagtatta aaagatatcc tgtttttagt tactacatta tctataatag
    23101 taatattatt gcttgtaaca aatataacta ctaatagtaa gataaaatca acaagtgaat
    23161 cttatttaaa aagtgacaaa aatagtgtga ggcaaaatgg tatccagagg agcacaaaga
    23221 gtagcacaaa aaatactgca tttaagacta ctatactaaa cactggaaag tctgattgca
    23281 tattggttga gataggtaac aaagtcataa tgattgatac aggagaagat aaaaatggaa
    23341 aacaaatagt ggataggtta aaagaaaaag gaataaatac acttgactat ttgattttaa
    23401 ctcatttaga taaggaccat ataggtggag tagatagtgt gttatctagt gttaaagtaa
    23461 agaatattat acaagcaaat tataagaaag atagtaagca atatgatgaa tatattgact
    23521 cacttaaaaa agctgatata gaaccagtgc tactaaaaga taatatgaat attgtaatca
    23581 atggtgcaga aataaacata catccggctt caaaaagcaa gtacgagagt tcaaatgatt
    23641 attcaataat cactaatata agctatggag cacataagtt tttatttgca ggagatgcag
    23701 aggaagaaag attgtcagag tttataaatg gaaatacttt aaaatatgat tttgttaaaa
    23761 tgcctcatca tggaagatat gacaaattaa ctgaaacatt tttagagtct atttcacctc
    23821 aatatgctgt tattacatgt tcagagaaaa aagaaccaga ggaaggtgtt ttaaaaatat
    23881 tggaaagatt gaatataaaa acatttttga cttctaatgg agaggtagtt atcaatagtg
    23941 atggtaagac attgagtgtg aatcaataat ttttttaaaa atatctaaaa aaatttaaaa
    24001 aaatcattag caaatattac cccttaaaca tagtatattt taggagctga aactccacat
    24061 acaaaatgac taggaggtaa catattatgt tggatagatt ttttggtgaa ggcggatttg
    24121 gtggatgtgc ttggtggata ataatattat tcttcttatt cttagcattc caagattgtt
    24181 gggctgaaat ggacttatgt gcatggatac ctttcttaat attattatta atactttgtg
    24241 aatgtggtga cgtttttgat ggaggatgtg gatgctaaaa aaatcaattt agatgattta
    24301 ataaagctta tggtgggtat aaataaaata ccaaaccaat cacaatctag tgtttgaagg
    24361 tagtcggaaa tcccccgcta ccttcttttt tttattgtta aaatttattt ttgaattatt
    24421 tcatttacat ataataattt ttacgataaa gtctgatata attaaaaaga aaataaaatt
    24481 tatttatagg agatgtaaaa atggctatag tggataagat tttcaatgag ataaaactta
    24541 tggttgcaag acttttattg ggaaaaaaat acagtgaata tgaagaaaaa gatttagtgt
    24601 ataatacaga agaagaagtt atacttataa ctttaaaaag attagttttt cagggaaatg
    24661 taaacgaagc agaagaaatt ttatttgata aagctaagag tgtaaatagt gaaaatatgc
    24721 agtatatagc aatagaattt tatactatgc ttatggaaaa gactgatgaa gaattagaag
    24781 ctatgaattt ttctaaacaa gaagtttatc aaggtataga agatattaga aaagtattga
    24841 atttagaata aaagatatat gaaaatattg aaataaatta atgctaaggt gagaatatta
    24901 tacttatata taaaaatata gtattcttat tttattagtt atataggtat atcttattta
    24961 ccataaaact atcttgaaaa aaattaatct taattgtata atattacttt gagtgaaaaa
    25021 gtattaacat ttttttataa gatgttttac taaaaaaata tatataaata tactgttatc
    25081 aacaagaaat ttaatttagt gaggtgttaa gatgaaagta ggatttgacc acaaaaaata
    25141 tttagaagag cagtctaaat atatcttaga aagagtaaat aattttgaca aactttattt
    25201 agagtttgga ggaaaattga tgggagacct tcatgcaaaa agagtacttc caggatttga
    25261 tgaaaatgca aagataaaag tattacaaca tatgaaagaa aaagttgaag ttgtaatttg
    25321 tgtctatgca ggagatatag aaagaaacaa aataagagga gactttggta tcacttatga
    25381 tatggaagtt ttaagattaa tagatgattt aagaggttat gaactagatg taaatagtgt
    25441 agtaattact agatttgaag gacaacctgc tacaactgta tttataaata aattagaacg
    25501 tagaggaatt aaagtttata agcattatcc aacaaaggga tatccgtcag atgttgagac
    25561 tatagttagt gatgagggat atggagcaaa tgaatatata gaaactacaa agccaatagt
    25621 agtagtcaca gcaccaggac ctaatagtgg aaaacttggt acttgtctaa gtcagttgta
    25681 tcatgaaaat aaaagaggta atgtagttgg atattctaag tttgagacat tcccagtttg
    25741 gaatgtacct gtaaaacatc ctttgaatat agcttatgaa gcagctacag ttgatttaaa
    25801 agatgtgaat atgatagatt cattccacct tgaaacgtat ggtgaaatgt cagtaaacta
    25861 caatagagat ttggaattat ttccagtgct taaaaaaata atagaaaaga taactggaaa
    25921 agaatcaatt ttccaatctc caactgatat gggtgttaat agagttggct ttggaataat
    25981 agatgatgaa gtaataagaa aagcttctat agaagaaata ataagaagat actttaaaac
    26041 tgcctgtgag tataaaaagg gacaagttga taaaggtgct tatgatagaa tgaaaatgat
    26101 tatggaagag cttaacttaa agccagaaga tagaaatgtt gtattacctg ctagaaacta
    26161 cagtaataaa ttgaaagaaa gtgccgacaa gaatgatact tgtcctgtag ttgcattaga
    26221 attagaagat ggtacaatat taactggtaa gggttctgat ttaatgaatg gaactgcagc
    26281 agtagtatta aatgccatta aacatttagc caatatatct gatgatatgc acttaatatc
    26341 acctgtaata ttagaaccta tcataaactt aaaaacaaag actttagcta gtagaaatgt
    26401 ttcacttagt tgccaagagg tgttaactgc acttagtatt tgtgctgtaa ctaatccaac
    26461 tgcacaattt gctatggaaa agttagcatt attaaaaggg tgtcaagctc attctactac
    26521 tatattaaat agagatgatg aacaaacatt tagaaaactt ggtatagatg taacttgtga
    26581 cccagaatat ccttcacaaa atctttacta tagttaaaat tatataaaaa aatatgggct
    26641 gttttaaagt aatagtttga gcagtccatt acaattataa taaaatcagt aggctgtctt
    26701 gtataagaca gtcttttgtt tttaaaacat cccataaatt aaatatatat actgttatcc
    26761 ataaggaatt ttaaatttag ttccttggaa tacctattgt aaagctttta tatagttttt
    26821 gcaagtgttt ttaaggattt tttataaatt atattgaagt taatggatta tagatggttt
    26881 tatttatgga aaatatgaat atataaagaa aataatgaaa aaataccaaa aagaaacata
    26941 agtttggtat aattaaaaag taatataaat aaaattaatc tatttatact ttaaaaggtg
    27001 ataataatga aacattatag aaaaataatt catatagata tggacgcttt ttatgcatct
    27061 atagaacaaa gagataataa aaaattaaaa ggaagacctg ttattgtcgg tggaaatcca
    27121 caaagccgag gtgtggttgc aacctgttct tatgaagcta gaaaatttgg tatccattca
    27181 gctatgccat cagctgtagc ttacaatagg tgtccatatg cagtttttgt aagacctaga
    27241 tttgatgttt ataagagtgt gtcagagcaa ataagagata tattttatag atacacagat
    27301 ttagttgaac cattatcttt agatgaagct tacttagatg taacaaaaaa taaaaaaaat
    27361 attgattcat caattgagat agcaaagcaa ataaaaaaag atatatttag agaagttggt
    27421 cttacttctt cagctggtgt gtcatacaat aagtttcttg ctaagattgc atcagactta
    27481 agaaagccaa atgggttaac tgtaataacc gaagaaaatg cccaggactt tttagataaa
    27541 ttacctgtga ataaattttt tggtgttgga aaagttactt caaatactct taaaaattta
    27601 ggtataaaaa ctggatatga tttaaggtgt ttaaatttat ttgaacttga aaatatattc
    27661 aaaaaaagag gttatgaatt atataaattt gctagaggaa tagacgatag accagtggaa
    27721 ccaaataggg ttagaaaatc tgttggggct gagactacat taagtcataa tttggatatt
    27781 gatgaagaag aaacacgcaa cattcttgat gaactttgtg aagaagtatg tcatagatta
    27841 aaaaactctg agaagtttgg aaaaacatta acattaaaaa ttaaatatga ggactttaca
    27901 aagataacta gaagccttag tttagaacac tatattgacg aatataatga tataagaagt
    27961 ggtgtagata atttgttgag aaatgttgag gttaatggaa aacaaattag gctattggga
    28021 gttacaatat caaacctaag tgataaaaaa gaaacttata aagatattac attatttgaa
    28081 tacatggata gtatccaaat gtgagttttg tttaaatgaa ataacactag ctttaatact
    28141 atataattga ggctagtgtt attttatgaa tatttttata ttttttgttt tttgacattg
    28201 tatattatat actatatata aatactttat atttgtagca atattcagac aaatagtgac
    28261 ctaaaaatcg tactttgttt acataaataa aatagtatga tataattata aaaacaactt
    28321 ataatattgg agaaggttgc ttgttcgaaa aaggggatga taaattatga tagagataag
    28381 aaatgtaaca aaaaaaatag gaaataatgt tatattagat gatatttctc tagttgtaga
    28441 aacaggtaca ttggtagttt tgattggttc aagtggttgt ggaaagacta ctactttgaa
    28501 gcttataaac aaattaataa aacctacatc tggtgagata tatattaatg gcaaaccaat
    28561 ttctcaggaa aatgaaatag agcttagaag aaaaatagga tatgttatac agaacacagg
    28621 cctattccct catcttacaa taaaagaaaa tatagagcta attccacgcc taaaaaagga
    28681 aaaatccgtt gaagaaattg aaaaaagaac gttgcaacta cttgagatgg taggacttga
    28741 tagtgatgaa tttttgaata agtatccttc agaacttagt ggtggacagc aacaaagaat
    28801 cggtgttgca agagccattg ctactgatgc tgaaataata ttgatggatg agccttttag
    28861 tgctttagac ccaataacga gaacatcttt acaagaacaa ttattttctc ttcaagatga
    28921 attgaaaaaa actataatat ttgtaacgca tgatatggat gaggctttaa agatagctga
    28981 taaaatttgt attatgaagg atggaagaat agcacaatat gatactcccg aaaatatact
    29041 tagaaagcct gcaaatgact ttgtaaaaga ttttatcgga gaagatagag tttgggataa
    29101 tccagaatat ataaaagcaa gagatattat gataaaaaat cctattgctg ttaattctac
    29161 tagaactgta actcaaggaa tagaaattat gagaacgagt aaggttgata gcttactaat
    29221 tatagataga gcaaaaacat taaaaggtat tgttactgta aaagatatga aagatattga
    29281 tgataagtca atattacttg ctgatattat gtcaagtgag cctttgcatg taaatgaagg
    29341 ggataattta gtagaaatac taaatgtaat gaatcgtaat tcggttggat atattccggt
    29401 tatttctgat gaaaataaac tggtagggct tattactaga agtagtttac tttctgtttt
    29461 aagtgaacaa ttcttagaaa tggaggtgag tgttcttggc taattttttt aactttatac
    29521 tattacaaaa agataagatt atagagcttt taatacaaca tatgagtcta actgttacat
    29581 ctattttaat agctataata gttggtgttc ctcttggaat aattatttca agaatctcat
    29641 ctcttagaaa gtttgtactt ggatttgtaa acttagtcca agcagttccg tctatggcac
    29701 ttttgggtct tcttgtacct atacttggta taggaagtaa accagccata tttatggtag
    29761 tggtttattc attactacca attgtaaaaa atacgtatat aggtataaca agtattgacc
    29821 cagtagtatt agaatcagct aaaggtattg gtcttacaag aaatcagaca ttatttaaaa
    29881 tacaattccc tttagcactt cctataataa tgggtggagt tagaatatct gcagttacag
    29941 ctgttggttt gatgactctt gcagcattta taggtgctgg tggtttagga tatttagtat
    30001 tttcaggggt tcaaactgta aataataata tgattttagc aggggcaatc ccatcatgta
    30061 taattgcact gttagttgat tatttattta gtaaaattga agttgcagtt actccaaaag
    30121 gattaaatcc aaaagcacct aagaagaatt atatagcact taaagtaata tctgtagtgg
    30181 ttgttgtttc aatgttgttc gttgttttta gttctagttt ttcaagtaaa aaagatacaa
    30241 taactattgg ttctaaagat tatacagaac aacttatact tggtaatgtt tatgctgaat
    30301 tagtagaaaa aaatacgaat cttaaagtta agaagaattt aaatctaggt ggttcatctg
    30361 ttgcgtttaa tgcaattaaa tctggtgagt tagacatgta tgttgactat acaggtacac
    30421 ttttggtaaa tgtaatgaaa catgctccga ttaaagatgc tgatgaagca tataatgttg
    30481 taaaagatac tatggaaaaa gaaaatcagt taactttact tgaccctctt ggatttaata
    30541 atacttacac attagctatg atgcctgaaa ctgctgaaaa gtatggaata aatactattt
    30601 ctgatttgac taaatatggt aaagaattta cattctcacc aactttggag tttgaaaata
    30661 gagaagatgg tcttgtaggg ctttctagag attatggttt aaaattcaaa gatgtaaaag
    30721 caatgaatgg aagtttaaga tatacagctt tagataataa tgaatctcag gttatagatg
    30781 catttttaac tgatggtctt attaaaaagt ttaatcttaa gatattagag gacgataaaa
    30841 atttctttgt accatattat gcagcaccat tagtaagaga agatactttg aagaaatatc
    30901 ctgagttaga aaaagttatg aatatgcttt caggaaaaat aaatgaagaa actatgagag
    30961 aacttaacta tcaagtggat gaacttggta aatcaccaga agaagttgct cattcattct
    31021 tagttaaaga aggcttagta taaaaaatta atagtttata tcaaaaaatt taagagagtg
    31081 tctcaaaatg aactttttag ttcatgaggc actctttttt atatgaaatc aaatatattt
    31141 tatcatttca acaataaaaa agaagattat ctttattttg agacagtctc ttatttttat
    31201 gtataccaaa accataccta cgatttttat ttataattaa gtttcaaata gaatgaacaa
    31261 gtacaaccaa ttttgaatat aaatatagta aatgtgctta tatacgattt tattgtctgg
    31321 ttgattgata ttgatagata gctttcttta ttgaatcgaa gggaggggga atttgttatg
    31381 gataactata agaaagtgaa gcaagtattg tggataattt tatttgctaa ttttgcagta
    31441 gcattattaa aaatcattat tggtaatcaa ataaaaagct atagtatgac agcagacgga
    31501 tttcattctt tgtcagatgg agcatctaat atagtggggc ttataggtat tttctttgca
    31561 tctaaaccaa aagataaaaa tcatccttat ggacataaaa agtttgaaat tataaccagt
    31621 ttatttataa gtggtatgtt gtttgttata gcaattaaga taattcttag tgcagtgtta
    31681 agaatagcta atccagttgt acctgctata actatagaaa gtttaattgc tttaattatt
    31741 acacttttta taaatatttt tgtatgcatg tatgaatata gaattgggac taaactaaat
    31801 agttatgttt tgatttcgga ttcattgcat acaagaagtg atatatttgt gtctctaggt
    31861 gtattggtta ctttagttgg tgttaagtta ggatttccag taataataga atctatagtt
    31921 cctattatta tttctgcatt cataatttat tcggcttatg gaatatttag gccatctatt
    31981 ggaattttgg tcgatagagt ggctgtagat gaggattata taaaagaaat tgtgtttgaa
    32041 tttaatgagg taagggatgt tcacaatatc agaagtagag gtagcaaaag ttctatttat
    32101 attgacatgc atgtaatggt agacccattt ataagcgtag agcaatctca tgatttaaca
    32161 cataaaattg agaaacaaat acaagaagaa attaatgaaa atgctcaagt aatagtccat
    32221 attgaacctt tttatagttt ttaacttagc tataaaatac aagttataaa aaaatataat
    32281 ttataaaaaa aatattatac cataaataat ttataaaaat tatttatggt ataatatttt
    32341 ctataaagaa attaagtctt aatatatcta aggaggaatt tacaatgaga tacgttgaat
    32401 atggaaagac agggaaaatg gtttcagtag ttggctatgg aggattaagg tttgatttag
    32461 aaaaaagtaa tcaagaaaat gctgatttag tcaaatatgc gtatgaaaaa ggtattaatt
    32521 actttgatac agcaccaggg tattgtgatg acagaagtga agatatattt ggactagcct
    32581 ttagacaaat gataaaggaa ggtaagaccg atttttatgt atcaactaaa gaaaagccaa
    32641 aagcatgtga tacatcagaa aaagctatag aggctgtaaa aaaatcaata gaacgattag
    32701 gcgtatctaa aataaatttt tatcatgttt ggaatattag aaagatggaa cattacgaac
    32761 tagcaatgag acctggaggt caatatgaag gattattgaa atgtaaagaa gaaggattga
    32821 tagaccatat agtattttca tctcatcaac caggagatga ggttatagat attctaagtg
    32881 aaaataagtt tgaaggtgta actatgggaa taaatatatt aaactttcca tataggctaa
    32941 aaggtgccaa atatgctgtt gataatggat atggtgttgt ggcaatgaat ccattaagtg
    33001 gtggaactat tccaaagtat aataaagaac tttcttttct atcaaaagat ggcgaaagta
    33061 ctatagaatc agctttaaga ttcaacatag gaatttcaca aataagtata tctttgatag
    33121 ggtttaataa aaaacaagat atagatgatg catgtaaaat tgcagacgaa aatagaattt
    33181 attcagatga ggatatacat gatattgaga ctagattaaa taagaatatg aacgaaatat
    33241 gtacaggttg tggttattgt aaagtatgtc caaaaggtat taatacccca gcctatatgc
    33301 ttttttataa tgaaaagcag atgtttaaaa agagtgatga agaaatgaca aagttagttt
    33361 atggcttagg acattggaat tacacaatga atagtaaggc aaaagctaaa gaatgtatat
    33421 cttgtggaaa atgtgaagtt gaatgtactc agcatttacc tataatagat agattaaaag
    33481 aaattaaaaa atgggaagaa gatggagcta atagtgttaa agtctaatta attttatact
    33541 atatttgaaa tttgtatagt atttagtaat gttttaaaat atagttttaa tatttaagga
    33601 gacagattat aattttgtct ccttaaatta tgctttaatt tgttatagtt taattccata
    33661 agtaacattg tatattttta tataaagttt ttcaaatatt ttacattaat attgcttaca
    33721 aattctcatt ttatacaaca ctaatctatg ttatataaac aatacttgac tgattataac
    33781 atcaataaag taaatattgt ggttgtaaat aaagagttat tcaattacaa taaaacaagt
    33841 aagaacatta tgaagatggc tattaaatat aaggaataaa ttgtaggtgt cagcaaatcc
    33901 tatataatga atggatggtg atatattgat gagtaaaata ttaaaatata aaaacgagat
    33961 gtttttgttt atattagttg taataactta cttaataata actaagatat ttttttctaa
    34021 gactactata ttttatgatt taaacaatac ttatgatgta ttgttagata cagatacagg
    34081 agttttattc aatttaaatg tatttgctat aagtcaagac aatagtaagc atatattgtt
    34141 ttcagcaatt atatcaattt ttgcatatcc aatataccta ttttgtactt caatagcaaa
    34201 tcctgggaca acagatttta atagtgccta tgggtttgga ctaatttgtc tacaaataat
    34261 aactagtgct atgtcaataa ctttagtctt taatcatatt aaaaagataa aaatgcagag
    34321 attaacttta attttactta ctatgataat gatattttct tttccacagt tatttatgac
    34381 tttaaatgta gagagattta tatatagcca attttcatta atatttttca tagttattgc
    34441 aaataagatg aaaggaaaaa attcttattt ggtagaatta gcagctattc ctctatttgg
    34501 aataactatt agtaatatat atttgtattt ttttaatatg atatttgagt ttaaattaaa
    34561 aataggaaaa atgttaaaac atttaattac atttatccta atggcatata tttgtgtagt
    34621 ttcaacgaag tcttatgaga gttttatgaa ccttggaaat gtaatacagt atgatacgaa
    34681 atttataagt ggagaaccaa ttttggaaaa gattgcaatg attatagaga gattattgta
    34741 ttcggttttt tattttcctg gagcaagtat taaaaaaggg ttatttttgc aaaatggaga
    34801 agttgctaca ataccagtaa ttcttacatt attagcttta tgtttttgtg ttttatcagt
    34861 tattgaaaat tcagaaaaaa gagttcctaa gctatgtatg ggaataatta tattcaatct
    34921 aactttacat ggtatagtag gatataatct agtcaattca agtattatgg ctataaattt
    34981 tagttttgca gttataattt tattggctta ctttacgaaa gcccttagaa aaaatgaaaa
    35041 gaatatgtat aatatatttc tatcgctgtt attggttact atagtaatca gtaatgtcaa
    35101 tggatttata gaaattttaa acatagggat aaaatcatat cctgtttaaa aaataatatt
    35161 gaaagggtag taagtttatg aaacagacca atacaagtat aaggcttctt actaaaattt
    35221 cagattatat aaagttaatg agaataaagc aatatataaa gaatttcttt gtattttcag
    35281 ctataatttt ttcaaacaac atactaaata taaatttatt tttaaatacg tttattgcgt
    35341 ttgtgtgttt ttgcctaatg tcatcatcag tatatgcact gaatgatgct atagacatgg
    35401 ataaagataa aaaacatcct aaaaaatgta atagaccagt ggcaagtgga agaataagca
    35461 aaaaaagtgc taatatacta tttgtagtat tagcgttaat ttcagtctgt ttatcaacag
    35521 ttgttagttt taatctttct ataattctca gtctctattt gataaacaat atattatatt
    35581 ctcttaaact aaagaatata atactattag atgtgttttc aatatctctt ggttttatac
    35641 ttagggttta tgcaggatgt gtagccataa gtgttagttt atcaaattgg ataattttat
    35701 gtacattttt cttatctctg tacttagctc ttggaaaacg taaaaaagaa atagaaactc
    35761 taagagatga tgcagttgaa catagaaaaa tattggaaga ttatgacata gaaaatctaa
    35821 atcaaatgat gatagttata ttaagttcta caattgtatg ttatgcattg tattctacaa
    35881 gtaatccaga aaagccacat atgatattta caacaatatt tgtagtttat ggtgtactta
    35941 gatataatta tataattaac actacaaatg aaaataatcc tactgatatt gtcctaaaag
    36001 ataatgcttt aaaaataaac gtaatcttat ggataattac atgtttaata atattgattt
    36061 tttagtgata tttttagtga taggatgggg aaatacttat gaaaaaaagt gtattattac
    36121 ttgatgtaga ttatactgtt ataaatactg atagcatgat agattttttt atttactctt
    36181 taaaaaataa aacctttaaa actattataa agttgccata cattattttt attctattta
    36241 tgtatttaat tagaatgata cccttgaaga aggcaaaaga ggcaatcttt tatccaatag
    36301 tagattttag tgaagaagat ttaaaaaagt tttttgatga ttgcataatg aaaaaaatta
    36361 acgaatctat gaaaaaggtt atttacaaaa ataaagaaga agataatgtt ataattatga
    36421 taactgcatc tccatatgca tatatgaaat attttaagta ttatggtctt gcagacgagg
    36481 ttataggcac ggagtttttt tatgaaaatt caagatataa aaatcaattc attggagaaa
    36541 actgtaaggg aattgaaaaa gtaaaaagaa taaaggctgt attaggtaaa cttgggatag
    36601 agattgatta tgaaaattca tatgcatatt cagactctaa gagtgattta ccaatgcttt
    36661 cattgactaa aaatgcattt ttagttagta aaaaggatgg tgaggttata gagcaaataa
    36721 attcataact taatgtcact tagaatagga gggaatagtt tgggatattt acacatatta
    36781 attttatcta tggttcctgt aacagaattg aggggagcca ttcctatagg tattgcaatg
    36841 ggcttaaatc ctatatgggt ttatgtattt agtgtaatag gttctacatt tgtatcgatt
    36901 cccttgatat tgacattcag acatgtatta caatttttaa gagggaagaa actatttaaa
    36961 gggattgctg atgtaattga tagaaaaata aactcaagaa tgaagaaatt aaaaagtgtt
    37021 tcgataattg gtataatact atttgtaggt ataccactgc caactacagg aacatggact
    37081 gcatctgcta tagcttccat attaaaaatg agaataaaag atgcttttat gggagtattt
    37141 cttggcaatt tgttatcagg ggttatagtt tcagctcttt ctttacatat aatataaaac
    37201 tatctaagta atatacttgg atagtttttt tatgagtata tgtgaaaaat ttttaataat
    37261 aaataaaaaa tgagataaag tatttaactt cagttagttc taaaatgttt actatggcaa
    37321 aagaaatata gtatagtatt acttgtaggg aaagtactct aaatttgtct gctaataaaa
    37381 tgaaattttt atatagaata aaattttagt gatacatttt aattattgga ttgaggaggt
    37441 tttaaaatgg aaaattcaaa cactaactta ggtagtgaaa gtgtgggtaa attattattt
    37501 aaacttgcta cacctgctat tatcgcacaa attgtaaatg ttttatacaa catagtcgat
    37561 aggattttta ttggtagaat ggaaaatgga gaagttgcta tggctggtgt tggagtggca
    37621 tttccaataa taattataat aactgcatgt agttatttaa tcggtatggg aggaggtcca
    37681 ttagctgcta taaaaatggg tgagcaaaac aatgatgagg cagagaaaat aatgagtaac
    37741 agtttttctg tattggtgat tttagcaata cttttgacta taggttttaa gattggaaaa
    37801 gagcctttac tttggatgtt tggagcaagt gaatctacaa ttggatattc aatggactat
    37861 ttaaatattt atttaatagg tacagtgttt gttcagattt caatgggtat gaatactttt
    37921 ataaataccc aagggtttgc tacaactgga atgatgacag ttgctatagg tgctttaata
    37981 aacataatac ttgacccgat ttttatattt ggctttaata tgggtgtaaa aggagctgca
    38041 ttagctacta taattgcaca aggcgtttct gctatttggg tacttatgtt tctctttgga
    38101 aagaaaagta tacttaaaat aaaaaagaag tatatgatac caaaagcaag tatcatctta
    38161 ccagtgcttg gcttgggaat ctctccattt ataatgcaat ctacagaaag tttagtactt
    38221 atagccttaa atagtaaatt acaaatgtat ggaggagatt tagcagtagg ttcaatggcc
    38281 ataatgagca gtataatgca aattcttatg cttcctaata tgggggttac acaaggagca
    38341 caaccaataa taagttataa ttatggttca ggtcaacttg atagagtaaa aaagacattt
    38401 aagttgtgtt tattgtcatg ttttacatat tctactattt tatggctttt attaatgata
    38461 tttcctgcat tttttgttag tatatttaat aagaatccgc agttacttag tatgactagt
    38521 tggagtataa aaatatattt tgctggtgct tttatgtttg ggattcaaat agcttgtcaa
    38581 cagacatttt tagcacttgg aaaagcaaca atatctttgg ttttagctct acttagaaag
    38641 attgtacttt taataccttt aatatttata cttccaacat tctttaatga aaaacttttt
    38701 gcagtaattt tagcagagcc agttgcagat ataacagccg ctactataac agcaatttct
    38761 ttctttatat tttataaatg ttttctatca aaacctaaag caataaaaga ataagatata
    38821 caatataaat tttttatgaa aatattttat tagataaaaa ttagaattt
//
LOCUS       DAYAKB010000031        38752 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.031, whole genome shotgun sequence.
ACCESSION   DAYAKB010000031 DAYAKB010000000
VERSION     DAYAKB010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.031"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..632
                     /locus_tag="ACGI3L_001925"
     CDS             <1..632
                     /locus_tag="ACGI3L_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF5808 domain-containing protein"
                     /protein_id="HFG9197634.1"
                     /translation="LGMSIFIAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIG
                     TDFCLMVLLYITSIGSIKSRIKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFF
                     TTLLSIKTKLLTAMNITTLLVIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNN
                     PNDPSLMVNKRFGIGWTINFGNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            752..1228
                     /locus_tag="ACGI3L_001926"
     CDS             752..1228
                     /locus_tag="ACGI3L_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFG9197635.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            1614..2081
                     /locus_tag="ACGI3L_001927"
     CDS             1614..2081
                     /locus_tag="ACGI3L_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFG9197636.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(2141..2713)
                     /locus_tag="ACGI3L_001928"
     CDS             complement(2141..2713)
                     /locus_tag="ACGI3L_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9197637.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(2776..3873)
                     /locus_tag="ACGI3L_001929"
     CDS             complement(2776..3873)
                     /locus_tag="ACGI3L_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFG9197638.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            complement(3887..4576)
                     /locus_tag="ACGI3L_001930"
     CDS             complement(3887..4576)
                     /locus_tag="ACGI3L_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFG9197639.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            complement(4741..5907)
                     /gene="rpoD"
                     /locus_tag="ACGI3L_001931"
     CDS             complement(4741..5907)
                     /gene="rpoD"
                     /locus_tag="ACGI3L_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFG9197640.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            complement(5925..7715)
                     /gene="dnaG"
                     /locus_tag="ACGI3L_001932"
     CDS             complement(5925..7715)
                     /gene="dnaG"
                     /locus_tag="ACGI3L_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFG9197641.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            complement(7970..8755)
                     /gene="aroF"
                     /locus_tag="ACGI3L_001933"
     CDS             complement(7970..8755)
                     /gene="aroF"
                     /locus_tag="ACGI3L_001933"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFG9197642.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            complement(8736..9242)
                     /gene="folK"
                     /locus_tag="ACGI3L_001934"
     CDS             complement(8736..9242)
                     /gene="folK"
                     /locus_tag="ACGI3L_001934"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFG9197643.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            complement(9235..9600)
                     /gene="folB"
                     /locus_tag="ACGI3L_001935"
     CDS             complement(9235..9600)
                     /gene="folB"
                     /locus_tag="ACGI3L_001935"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HFG9197644.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            complement(9611..10402)
                     /gene="folP"
                     /locus_tag="ACGI3L_001936"
     CDS             complement(9611..10402)
                     /gene="folP"
                     /locus_tag="ACGI3L_001936"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFG9197645.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            complement(10466..11038)
                     /gene="folE"
                     /locus_tag="ACGI3L_001937"
     CDS             complement(10466..11038)
                     /gene="folE"
                     /locus_tag="ACGI3L_001937"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HFG9197646.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            complement(11064..11765)
                     /locus_tag="ACGI3L_001938"
     CDS             complement(11064..11765)
                     /locus_tag="ACGI3L_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197647.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            complement(11799..12542)
                     /locus_tag="ACGI3L_001939"
     CDS             complement(11799..12542)
                     /locus_tag="ACGI3L_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HFG9197648.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDIKYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FVKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            complement(12532..13881)
                     /gene="pabB"
                     /locus_tag="ACGI3L_001940"
     CDS             complement(12532..13881)
                     /gene="pabB"
                     /locus_tag="ACGI3L_001940"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HFG9197649.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            complement(13883..14467)
                     /locus_tag="ACGI3L_001941"
     CDS             complement(13883..14467)
                     /locus_tag="ACGI3L_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HFG9197650.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            complement(14491..15210)
                     /locus_tag="ACGI3L_001942"
     CDS             complement(14491..15210)
                     /locus_tag="ACGI3L_001942"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9197651.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            complement(15238..16302)
                     /locus_tag="ACGI3L_001943"
     CDS             complement(15238..16302)
                     /locus_tag="ACGI3L_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFG9197652.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            complement(16446..17255)
                     /locus_tag="ACGI3L_001944"
     CDS             complement(16446..17255)
                     /locus_tag="ACGI3L_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFG9197653.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            complement(17497..18363)
                     /locus_tag="ACGI3L_001945"
     CDS             complement(17497..18363)
                     /locus_tag="ACGI3L_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9197654.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            complement(18883..19572)
                     /locus_tag="ACGI3L_001946"
     CDS             complement(18883..19572)
                     /locus_tag="ACGI3L_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFG9197655.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            complement(19565..19936)
                     /locus_tag="ACGI3L_001947"
     CDS             complement(19565..19936)
                     /locus_tag="ACGI3L_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFG9197656.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            complement(20118..21515)
                     /locus_tag="ACGI3L_001948"
     CDS             complement(20118..21515)
                     /locus_tag="ACGI3L_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9197657.1"
                     /translation="MEVSIILVKDIKQDIESMPRKILDISLIEDNKSDLTFFNIEEED
                     GDETLKALKQSYVTTNYKEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKN
                     YITSAINMVNKALEINPKDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKY
                     VNLISSEDFKTFLGRYNHSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDK
                     LGNVKKREGYLDKLKELDKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCV
                     LIGMGIYLIQSKKRIENLNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEP
                     EREITVADEEDLYYQALNLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKL
                     LGNKDEAIKYYKKYINTYTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPD
                     SMYNNSKIKEILSEK"
     gene            complement(21646..22239)
                     /locus_tag="ACGI3L_001949"
     CDS             complement(21646..22239)
                     /locus_tag="ACGI3L_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197658.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            complement(22304..23773)
                     /locus_tag="ACGI3L_001950"
     CDS             complement(22304..23773)
                     /locus_tag="ACGI3L_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HFG9197659.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            complement(23888..25279)
                     /locus_tag="ACGI3L_001951"
     CDS             complement(23888..25279)
                     /locus_tag="ACGI3L_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFG9197660.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIKKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            complement(25445..25735)
                     /locus_tag="ACGI3L_001952"
     CDS             complement(25445..25735)
                     /locus_tag="ACGI3L_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197661.1"
                     /translation="MSGLKKILRILVISMMICFAMTFALVLINSVMGVHIGLDYYFLM
                     GSVLTVCLTIGIVLCNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            25959..28088
                     /locus_tag="ACGI3L_001953"
     CDS             25959..28088
                     /locus_tag="ACGI3L_001953"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HFG9197662.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(28315..28914)
                     /locus_tag="ACGI3L_001954"
     CDS             complement(28315..28914)
                     /locus_tag="ACGI3L_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viroplasmin family protein"
                     /protein_id="HFG9197663.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(28932..32051)
                     /locus_tag="ACGI3L_001955"
     CDS             complement(28932..32051)
                     /locus_tag="ACGI3L_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFG9197664.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANKIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINFIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            32272..33096
                     /gene="pdaA"
                     /locus_tag="ACGI3L_001956"
     CDS             32272..33096
                     /gene="pdaA"
                     /locus_tag="ACGI3L_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HFG9197665.1"
                     /translation="MKKDSLKKYIMIGAFALTLFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            complement(33193..33978)
                     /locus_tag="ACGI3L_001957"
     CDS             complement(33193..33978)
                     /locus_tag="ACGI3L_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9197666.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEGGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(34078..34212)
                     /locus_tag="ACGI3L_001958"
     CDS             complement(34078..34212)
                     /locus_tag="ACGI3L_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197667.1"
                     /translation="MNISRKAMKIIELAQKIANKRGISVEEAWSEAVTEYKNKYEHIA
                     "
     gene            34443..34808
                     /locus_tag="ACGI3L_001959"
     CDS             34443..34808
                     /locus_tag="ACGI3L_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9197668.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            34886..35440
                     /locus_tag="ACGI3L_001960"
     CDS             34886..35440
                     /locus_tag="ACGI3L_001960"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFG9197669.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYYK"
     gene            35660..36334
                     /locus_tag="ACGI3L_001961"
     CDS             35660..36334
                     /locus_tag="ACGI3L_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFG9197670.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      36689..36785
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            36839..37015
                     /locus_tag="ACGI3L_001962"
     CDS             36839..37015
                     /locus_tag="ACGI3L_001962"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197671.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(37186..37425)
                     /locus_tag="ACGI3L_001963"
     CDS             complement(37186..37425)
                     /locus_tag="ACGI3L_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197672.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(37540..38379)
                     /locus_tag="ACGI3L_001964"
     CDS             complement(37540..38379)
                     /locus_tag="ACGI3L_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9197673.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITKYLYFNGL
                     DGK"
BASE COUNT        12534 a         6558 c         3981 g        15679 t
ORIGIN      
        1 ctttgggaat gagtattttt atagcattta attataatca attgccagac tcaattgcca
       61 ctcattggaa cataaatggg tctcctgatg tttttataga taaatcattt cttaatgtat
      121 ttaaattaat cggtactgac ttttgtttaa tggttttatt atatataact tccattggat
      181 ccataaagtc aaggattaag atagatacaa atagaattga agaaagtaga gttgaaaaca
      241 ttaaatattt aaataaaatt ggttatttgt ttttaatatt gatgattata atgacaacac
      301 agttttttac tactctttta tcaataaaaa caaaactatt aactgctatg aatattacaa
      361 cgcttttagt tataatttat ttaatagcaa catatattaa ttccccaaat ttaaaattca
      421 actcatctta ttctccagaa gaagatgaga agtattggat agcaggcatc atgtataata
      481 atccaaatga cccatcatta atggttaata aaaggtttgg tattggatgg actataaatt
      541 ttggcaatcc tcttggaaaa atactatata ttgctatagc tttactttta attttttcat
      601 tgtttagcct aataaaatct ctcttacttt aaaataccat aaaaggtatc ttacttgtat
      661 tattgggtat tatattttgt aggataagaa atatttcata ttatcgttga agtatagtat
      721 ttatatatta ctaagaatgg agattttcat aatgttgtca aaagctgaaa tcaaatattt
      781 taatgaatgt gcttctgaga tactttcttc tgaaaaagtt caacttatga gaacatttcc
      841 tcatcatggc aatgtttcat gtcttgaaca tagtttgtca gtagcatatt atagttatct
      901 attatgtaaa aaattgcact taagtgttga tattcaaagt gttattagag gagctttact
      961 acacgacttt tttctttatg attggcatta caaaggtgat agaaaaggat tacatggatt
     1021 tactcaccct agagaagcat taaaaaatgc aactttattt tttcaaataa atgaaaaaga
     1081 aacggacata attttaaaac acatgtggcc acttactgtt aagccaccta gatacaaaga
     1141 agcatttatt gtatgtttgt tggataaatt ttgctgttta gttgagactt taaagataca
     1201 ttctttatta tctccttacc atgtatagga caattcccac aacactttta taacttaatt
     1261 ttgaagaggt attaagtatt atattcaact tgatacctct ttactattta ttattttata
     1321 taataatatt ttctttataa tatcgttata aacaacaact tctaccctcg ataacttccc
     1381 cttcttatag acatgcttac taccttaaat aacaagaaac cagctattaa atttattagt
     1441 attatttgta ctactctaac aataatatca taaataaacc tccaaatagc ttctctttca
     1501 ctacctttta tcttaaacta tatttttttc ttaaaatttg taaaaaacat agcataatct
     1561 ttataaatgt tctaaaattt aatttaagca tcaaaattag aaaggatgat attatgttta
     1621 aagaaatgag attgaaaaaa agagaaatga caaaagaaga tactgttgaa gtattaaaaa
     1681 atggtgaatt tggtactttt tccactatat ctgaaaatgg ttatccttat ggagttgctg
     1741 taaattatgt atactttaat gattctattt actttcattg tgcaagaaat gggcataagt
     1801 tagataatat atcgaaaaac aacaaagttt cttttttagt agttgctaat gaaagtgtta
     1861 ttccagataa atttagtact acttattcta gtgctatagt ttttggaaaa gcttgcactg
     1921 tagaaaatga agaaaagaaa aatgctcttg tagaaataat aaaaaaatat tctaaaggat
     1981 tctttgaaga aggcatgaag tacatagaga aggatatgaa cttaacaact gttgttaaaa
     2041 tagaaattga ccatatttct ggtaaagctt cacgtttata attaagtaaa aatacctaaa
     2101 agtatataca gtcgctttta ggtattttta tatgatattc ttatatgtta agtcttttta
     2161 ggtaatctct tatacctatc ttggcatcat catttggcct tatatcagaa ttatctcctg
     2221 ctatatgaag tattccatac gctggataac ctcctcttac tgaacatgga actgacaaaa
     2281 gagtcattcc catatgttgg gcaaatatat tcatagcttg caaagctaat tctcctcctc
     2341 catgttgtga acctgctgta gcaaaacaac caaatatttt accactcaaa ggagcaccta
     2401 cccaaatatc agaaaaacta tccataaaca tcttcattgg tccagataca tttccataat
     2461 atgttggtga acccataaat atagcatcat aatctaatat ttcttttcca gatttaatta
     2521 catttatact ttcaaattcg tctttgtatt ctttggaatt tatcaaataa tattgaggaa
     2581 gtgtttttgc aacttcgtca cttactctaa atatatctac ctcgatattc atttcttcaa
     2641 gcgcttcttt atattctcta gctaataaat atgtactccc acaaacacta tgaaaaatta
     2701 ctgctacttt catcattatc cccctaatta aactcaaatt tattttttat atagtatttt
     2761 tattatcaaa cactgctaaa tagtactaaa tggattcaaa tatacattac tctttattac
     2821 ttcaatttca ctaaattcat ctaaaaatct cttcataaca tttttgaata tatcttctgt
     2881 atcaaaatga ccacaatcca ctatacacat tccaatatca agtgcatctt gtgcctcatg
     2941 atactttaca tcacccgtaa ttagtacttc tgcaccttgt ctcttagctt tttttacaaa
     3001 ttctgaacca gctcctgtta caacggctac tttcgttatg tctgtactaa ggtttccaac
     3061 tactcttatg tgtttcatat ttaatttctc ttttattttc cttgaaagac tttctaatgt
     3121 catactttta tcaagtttac ttattctacc tagtccaaat atctcacctt tattttctaa
     3181 cttgtacaaa tcatatgcaa cttcttcata aggatgtgca tctaacatag aacttattac
     3241 cccacctaaa agcttctgtg gtactacagt ttcaatttta acttcattta cagtttctat
     3301 atcatttaca cttccaagaa acggattaga gccttctaat ggcttaaatt gtccttcacc
     3361 ttctgttgaa aacgtacaat cactataatt ccctatatga cctgctcctg aattacttaa
     3421 aacctttcta agttcatctg aatagttatg tggaacgtat actgctaatt tatacaaatt
     3481 ttcgctttta gttatatcta aaacctttga attaccaaat tccataattt ccataaaata
     3541 gtcatttaga ccatcaaatg ctatatcaaa attcgtatgc atagaataaa gtgatatatc
     3601 atttttaata agtttttgga taagtctgcc ttttaaatct ccactattaa ttttattaat
     3661 tttcccaaat ataaaaggat gatgtgtcac aattaaatct atatttttgg atatagcttc
     3721 atcaataaca tcttcattag cttctaaaga taccaatacc ttttttacat ccatatcaaa
     3781 atctccaact ataagaccta cattatccca atcctctgct aagtttagag gatacttttt
     3841 ttcaattttt ctagttagac tctttaatag catatatacc tcctatttat tttattaaat
     3901 tttcaagttt ttttattgca acttcgcttt cctttctctt cttatctata gcttccccat
     3961 ttttcccttc taatttatta actatagaac tatatgtctt tatctttttt tctataaaat
     4021 cattaaaaag agaatctttg ttttctaaaa gctttattcc aacctcataa tatatctcat
     4081 cttctattat agtattttta cctgtatatt tggcaacaat tatctcatat attctaaaat
     4141 cttctctcac taaaacttct tctaaaattt catatccgtt gtttaaaagg taatatctaa
     4201 gttcttcttg tgcttgcatt ggctgtaata ttaatttttc tacattatgt gctacttctt
     4261 ttttagcttc gagaagctca cttatcaaga ttccacccat accagcaatt atcacttctt
     4321 ctacttcccc tatttcaagt atctctatac cagaacccaa tcgtaaatca actttatcta
     4381 aaagattgtt ctgtatgact tctttatgtg cattgtcaag aggtccttta ttaacatccg
     4441 ctagcactgc aaatggtact tttccctctt ttaacaaata tactggtatg tatccgtggt
     4501 ccgttcctat atcagctatt tttttaccat ctgacactaa tgatgctatt ttcaataatc
     4561 tatctgttaa tttcaaatat aattctcctt tcaattccct ttatttatag gatttaatcc
     4621 aagttataga tattagactg aaataactac aaaaataaaa ttaaatcttt actacaaaat
     4681 agccatgaga tatcacttat ctcatggcat ttatcacaaa aacatcaatg atgtatcttt
     4741 ttagtctaaa taatctctaa gtttttttga tctacttgga tgtcttagtt ttcttagtgc
     4801 ttttgcttct atctgtctta ttctctctct agttacatca aactcttttc caacttcctc
     4861 aagagttctg gctctaccat cctcaagacc aaatctaagc tttaatactt tttgttctct
     4921 atcatttaat gaaccaagta catcttctat ttgttctttt aataaagaat atgctgctgc
     4981 ctctgctggg gctggagcat catcatctgg aataaagtca cctaaatggc tatcttcttc
     5041 ttctcctatt ggtgtttcta aagacacagg gtcttgagct attttcatta tttctcttac
     5101 tttatcttct gtcatttcca tttcttttgc aatttcttct ggttttggat ctcttccaag
     5161 ttcttgaagt agttgtcttg atactcttat tagcttattt atagtctcta ccatatgaac
     5221 tggtattctt atagttctag cttggtctgc aatagcacgt gttatagctt gtcttatcca
     5281 ccatgttgca taagtactaa acttatatcc ttttgtatag tcaaattttt cgactgcttt
     5341 tataagacct aaatttccct cttgtattaa atccaagaaa agcatacctc ttcctacata
     5401 tctttttgct atacttacaa ctagtcttaa gtttgcttca actaaccttt gttttgctat
     5461 ctcatcacct tcgtgcatcc ttctagcaaa ttctacttct tcatgtggtt taagtagagg
     5521 aatttttcct atttctttta agtacattct tacagggtca tctatactta tcccttttgg
     5581 taaagataaa tccacagttt ctatttctat tgcagaagag tcatcatgtg aaattgcctc
     5641 tgcatcttca tctaagtggc ctatacttaa atcgtcatca gcaaccgaaa aatctatatc
     5701 agctttatag ttttttgttt ctgttatttc tattcccaaa tttcctaaag tctcataaag
     5761 attttctact tgatccttat caagttcagt ctccgaaaaa gcttccatta tctctgcaag
     5821 tgtcagagaa ccttgctttt ttcctttttc tattaatgtc ttagcagtaa ccttttttaa
     5881 ctctttttta ttcgatttat tttccacact caaacctcct ttctctacaa gctctttaaa
     5941 attttattta tctcaactat ttttaaagca atttccataa ctctaccatc tacctctttc
     6001 atatcattat tattttctaa ttcttgttgt tctctcaaca agctattaat ttgctcttct
     6061 aatgagtttt ttctgatatt tgttattatt ccttctattt cttttgtgtt ctctaagttt
     6121 atactattca aagaaattga atttaattct tttaagtatt cttcggatat gtttaaactt
     6181 ttcaatttgt caatagttat tttgtccaat tcttgatttt taatcatgta atttaaaatt
     6241 tctttacttt ctttcaataa aaaatcactt tcttctactt taagtaacgc tatttctcta
     6301 atttttttgt cttctaacat tatttttatt agagtttctt caactaattg ttttccgtct
     6361 tgtctgactt cgactttttc aattactttt tcttctattt tcttttgatt tttgttatta
     6421 tatggcttat tgtaattttt accataaact tctctcttta tagactcgac attaatatct
     6481 atttgattgc ttaaatactt tgtataaaaa tcaatttcaa caggacttgt caattgtttt
     6541 ataattttag aagcttcttt tgcgaacttc actcgttctt catctttttg aatgttaaat
     6601 tcttttttaa gatgatctat tttatatttt atgtagtgag tagaaacatc catagctttt
     6661 ttataatcac taagtccgta ttttcttaca aattcatctg ggtctttagc atcttttaag
     6721 tctaacactt ttacattgat acctaattta gtaagtatat ctatagctct taaagtcgct
     6781 tttattcctg cttcatcaga atcataagat ataatagcag tgtccgcata tctctttatt
     6841 aaaatgcctt gttgttcagt caaggctgtt ccaagggttg ctactacatt ttttatacca
     6901 tactgataaa gtgaaattaa atccatatat ccttcaacta agactatagt tttactttct
     6961 aaattttttc tagcaaaatt taatccgtat aagttctgtt ttttattaaa aattaatgtg
     7021 tctggagaat ttaagtattt tggcaaagaa tcgtctaata ctcttccccc aaatcctatt
     7081 atatttcctc tataatcgaa tataggaaac ataactctat ttctaaattt atcatagcaa
     7141 ttagttccat ctctattttt tgcaattaga ccgcactcta ataagtcttg ttttttatat
     7201 cctttactga ttagagtatt cataagtgaa ttccatgaat ccaaagaaaa tcctaaacca
     7261 aatttcttaa taattttatc atctagtcct cttattctta aatattcata cccaagattt
     7321 ttgcttccca ataagtttga aagataaaat ctagctgctt ccgtatgaat atcttgaaat
     7381 ttcttagatt tttctatttt aatcctagtt tcttcattca tgttagtgtt aatttctata
     7441 ccgcatttat ttgctaaaat ttttacagca tccataaaat ccaaattttc cattttcatg
     7501 acaaaattta ttacgtctcc accttcacca caaccaaaac acttataaat ctgttttgat
     7561 gtatttatat aaaaagaagg tgtcttttcg ccatgaaatg gacataatcc tttgtaatta
     7621 gctccagatt gttttatatt catatattca gatattatac ttgctatatc gcatctagct
     7681 tttatttctt caataatgtc ttttatatca ttcatattat caccttctgg tgtaattttt
     7741 tgtgttaaca tttctattct acactatatt ctaaatttgt caatcactca atatacacaa
     7801 ttcgactttt tttattgata tccttcttat taatcaaaaa atttttattt tttatattaa
     7861 ttctatcaat attaaatctt tatttatatt aaataatcta actatcaaat tataacttat
     7921 aaatttacct tagcaacgat tacgaataaa aaagaggctc ttgcctcttt taataattat
     7981 taattgattt cattaaatct tcaaattcat taaagcaaag agattgagca ccatctgaca
     8041 aagcattttc tgggtcagga tgtacttcta ccattattcc atctgctcca catgcaaaag
     8101 atgccagtga cataggtttt accaaatatc taactccagt ggcatggctt gggtctacca
     8161 caacaggaag acctgtttcc ttttgaataa tgggtaccgc agctaaatct aatgtatttc
     8221 tagtataatc attatacgtt cttatacctc tctcacacat tataatatta ctatttcctt
     8281 ctattgctat atattcagaa gcacctatcc attcagtaat tgtggatgct attcctcttt
     8341 ttaacataac aggtttattt tgttttccca cttcacttaa aagagtaaag ttttgcatat
     8401 ttcttgaccc aatttgaatt atatcactta tactatacag ttcgtccata tctcttacat
     8461 ccataagttc tgtaataaca gccataccaa cttcgtcttt aactgctttt aatatttcaa
     8521 gaccttcttt ttttaatcct tgaaatgaat ttggcgatgt tcttggcttg tatgctccac
     8581 ctcttaaaat gtttgctcct tgacttttta caaatttagc agtctccaaa agttgctcat
     8641 aactctctat tgcgcatggt ccagctatta taagtttatc tttttttaca gttatctttt
     8701 tgttatttgt atttatctct atctttgaat tattattaaa taggttttct ttcataacct
     8761 acaagctcct ttacttcttc tctttcttca gcagatagga ggtttaaatg ttcttttatt
     8821 gttttttcat ttattataag ttcttcattt aaatccataa gtggtatcaa aacgaaagct
     8881 ctatcttgaa tccttggatg aggtattgtt agtctttcat cagtggaaac tacatcatta
     8941 aaaaatagta cgtctacatc tatagttctt ggtccccaat gaactattct ctctctgtgt
     9001 agttctctct ctatttcttg acaatattct aacaactcat aaggttcaaa ctctgtttct
     9061 atttctacac acatatttag aaaatctgct tgttctgtat atccccatgg ttttgtttcg
     9121 tataagcttg attcttttac tttatatata gaatcactat ttttcaaaag ttcacatgct
     9181 cttgataaat tatcaaatct atcacccatg ttagtaccta ttcccaaata agccttattc
     9241 atctcttgtt ctccttatct caacaccaaa atagtcataa ataccattta caggagcctc
     9301 aggctttcta actctgacca taactccatt tataagtata aatttattca agacttcttc
     9361 agcaatattt tccgctaaag cctccaaaag attaaattgt ttattttcag taatatcttt
     9421 aacaacattg taaacctcgg catagcttac agatttattt atatcgtcac taagacctgc
     9481 ttctcttgaa tcaatataaa gttccatgtc gacaaagaat ttctgaccta gaaaattttc
     9541 ttctttaaga acaccatgat atccatagaa tcctagatta ctaagtaata ttttatccat
     9601 tatattatac ctactttcta tatattgcat cagtcattct agctgccatt aaattttcat
     9661 aaacatcatg tactctaact atatctacgc catctcttat accaagaaca gtagtagcta
     9721 ttgtaccttc taatcttttt ttaggctcaa ctggaagtac ttttcctatt actgattttc
     9781 tggatgtccc aagcaaaata ggatacccta aatcttttaa ttcatttaat cttctcaata
     9841 cttcaatatt ttgttcaaaa tccttgccaa atcctacacc tgggtcaagt actatttttt
     9901 ctttttttac accacaactc attgccattt ctatacttac cttaaaaaag tcttttattg
     9961 actccattat atctttgtca tagtttgtcc catcttgatt atgcattata cacacttctg
    10021 catcatattt tcctattaca gaagccatat ttttatcttt tctaagaccc caaacatcat
    10081 ttaccatagt gacacctaat tttaatgctt cttctgcaac atctgcctta taagtgtcta
    10141 ttgatattgg tatatccaat tcctgtttaa gtttttttat tacagggatt actcttctta
    10201 gctcttcgtc tgagtctaca tagctatgac ctgggcgtgt agactctcct cctaggtcta
    10261 ttatatctgc accttggtca accatatctt ttgcatgttg tattgctatg tccaagttat
    10321 taaaatctcc tccatcagaa aaactatctg gagttacatt taatattccc attatataag
    10381 ttcttttacc ataatcaaac acaattaatg acactccctt aaattaaatt ttatctcaat
    10441 aaatgattat atctataata aattgctact tcatagtaat caaactcata gcctcggctc
    10501 tagacgcaat gtccttttca aatattcctc tcactgctga tgtaacagtt tttgaacctg
    10561 gtttttttac gcctctcatt gtcatgcaca tatgttcagc ttctactact actaagacac
    10621 cataaggttg taattcttcc attattatat ctgcagcatt tttagtgatt ctttcttgta
    10681 attgtggtct ttttgccaat gtatctatta ctctagcaag tttagaaagc cctgtaagtc
    10741 ttcctccttt tggtaaataa gcaatatgag cttttccaaa gaaaggaact agatgatgct
    10801 cacaacatga ataaaatgga atatctttta ccaatactaa ctcttcatgt ttttcatctg
    10861 caaaaagaac ttttaaatgg tctcttggtt cttcactaag accagagaat atctcttcat
    10921 acatcctagc aactctattt ggagtttcga ttagaccttc tctatctggg tcttccccaa
    10981 ttgcctctag tatttctctt actgcatgtt gtatcttttc tttatcaact ttattcattt
    11041 aaactccccc cattgatttg tgactagaag attagtttta taacctcttt tgtctcaatt
    11101 tctttaaaaa tataattata aacatctaaa agtctttgat agtcataatt ttcacttact
    11161 tttgacacta gttcaaaaag ctcattattt tcttttttta aaacttttag caattttttg
    11221 tcttttggta cccatttatc atttatatta aagtacccaa ttattatatc ttttaaatat
    11281 aaattcgtca aaaaatgata ttcaaaaaca tcaaattttt ctttattttt taaattcgat
    11341 atttttgctc caatatcttg ctttataaaa gacttttcct ctaatgacat tttactgggt
    11401 ccttctaagt aaatatttct acttatatct tttataatat gtgatatatt ctccctatca
    11461 aacagtactt tagcatcttt catttctttc acaaagaaat attccctatt tgataataat
    11521 ttttttacac catcttttga aaagtaattt acatcaaatt ctattccctt ttttttaaac
    11581 agtattctct cttgtttttc cccttctttt acaaaaacga acacatcaat atcgtttatc
    11641 tctacatcat aaagagtaaa atctacgtct ttactagaac ccactaaata tacagccaaa
    11701 gtgttttggt tttctattat tttagttatc tcttcattgt atacttcata aatacaacct
    11761 atcatctttt gtctccaaca aattgttaat attttaattt attctaataa cttcactatt
    11821 ttatcaaaaa caacattttc tttattaaat tttattttgt caatttctgt aacctttata
    11881 gcgcccataa gactatttgt gacaaaaaca aaatcaaaac tactaatttc tgatatatta
    11941 atttcatttt ctatcaactc tatatgtaat tcgtcacaaa tctctataat cctttttttt
    12001 attattccat ttaatatcgg taatctatca ctaggagtgt acactctttc tccttttaca
    12061 aagaaaatat tgctcataga acattctaat attacacctt ctgaatttaa aaatatacca
    12121 tcattataac cagtcttatt tgcgatattt ttggtatata tgttttcaaa ataattagta
    12181 gtcttatgtc tatgaattaa actattcccc ctaactattg gagatatagc taatttaaac
    12241 cccttctcat acgtctcttg attatatgga atatccctaa tagatatatt ataaccttca
    12301 tcaaaaacag taattctaag tgctttatta atgacatttt ctttttttat atatgtaaca
    12361 atttcattta tcaagaaatc ttttttatat tttatatcta aatccaaaca atttattgaa
    12421 cttagcattc tttctatatg gatatctaaa tctactgcta ttccattttt aactctaata
    12481 gtttcaaaca aaccaattcc aaatttactt aaactactat caaaacctac attattcttc
    12541 ataatatccc ctcaaagcct tcattatgga tttagcttta tcaagtgttt cttgatattc
    12601 ttcatctggg tcagaatccc aagtcattcc tcctccaact tgaaaataga cttttttgtc
    12661 atttttgatt attgttctaa ttgctatatt aaaatccata tcaccattaa aacctatata
    12721 acctattgaa ccagtatata catttctttg cgttggctct aattcgtcta taatttccat
    12781 tgctctaatc ttaggtgctc ctgttataga cccccctgga aaagttgctt ttattacatc
    12841 agtagcatct ttatcatctt ttaactcacc tacaactgtg gaaactaagt gatttacatt
    12901 tgcatatggt tcaattacaa atagctctgg aactttaaca cttccagttt tagatattct
    12961 cccaatatca tttctttcta aatctactat cataagtagt tcagctctat ctttttcact
    13021 atttctaagt tcttgttgaa gtcttaaatc ttcttcttta tctttccctc ttggacgagt
    13081 accttttatt ggtctagttt ctattctctt attaacacat cttataaatc tttctggaga
    13141 atttgataat atatgtgcat cttcaaagtt taagaatgcc ccaaatggtg ctgggctaaa
    13201 tcttcttaag tccctataca attcaaagct tgtaagttct gtttctccac tgaacctttg
    13261 tgttaaatta gcttgatata tatctccttg tcttatgtac tctctaacac tttgaactgc
    13321 atttttaaat tcttcctttg taaaattaga tttaagtctt ataggtgtta cttctttttc
    13381 ttcataacat atgctatcta tacctttttt ctcttctttt aatattcttt gttctatatc
    13441 atctattatc ttttcttcta attcgatatc tatgtttgga gtagctatat aagttttttg
    13501 cacaagatgg tctataacta ttacatgatt ataaaatcca aaatacatat caggcatctc
    13561 aatatcatct acagcagttc taggtaaatt ttctatgtaa ttacctaaat cataagataa
    13621 atatcccaca gcacctccta caaatggaag attagtatca tttacaaccc tatacttatg
    13681 tagttcttct tttaaaactt ctaaaggatt ttcatcagta tctttatact ttaatacctt
    13741 aaatggttgg ctacttataa aagaatatct tcccaatttt tctttgtcca tagcactgtc
    13801 taatataaaa ctgtcatgtt catttctaaa aatagtaaat atctcaaaag aatttaattt
    13861 agtatttatc tctcttatca tattacatat gtaccctttc tctagcttct gttataaaat
    13921 ttttaagcat ttcatgacca tactctgaca aaatagcttc tggatgaaac tgtactcctt
    13981 ctattaaata tttcttatgc ctaatcccca ttatttcccc tttatcagta attgctgtaa
    14041 tttctaattc ttttggaact gtattggagt caactattag tgaatgatac ctagtgacat
    14101 ttaaaggatt tttaagtccc ctaaaaactc ctttattagt atggttgata ctatatactt
    14161 ttccatgcac aggctgttgt gcttttataa tatctcctcc aaaaacatgt ccaatagttt
    14221 ggtgacctaa acaaattcct agtataggtt ttttcccctt aaaatgctca acaatatcta
    14281 tgcaaatacc agcttctttt ggagaacacg gtcctggaga taacacaatt acctctggat
    14341 ttagttcttc aatgtcactt attttgattt cattatttct ttttactaca actgtttccc
    14401 ctaattcttc tatatattgg actaggttgt atacaaaaga atcataattg tctatcataa
    14461 gaatcatact gtaaatctcc cccctaaaaa ttattttatt aactcagaaa ctgttacaaa
    14521 tttaaaacct ttttcaatca tttttggaat aaacatatct aaagcttcaa ctgtatcatt
    14581 agttgcataa tcatgcaaaa gtattatatc tccattttgt actttattaa ttattttatc
    14641 tgcaatgcta ttagctcctg gatttttcca atctttcaca tctacacctg tccataaaac
    14701 aactttatag tcatgctttt ttgcaatttc tattaattct ttttctctat aacttccaaa
    14761 tggtggtcta aataatgtcg gtttttttcc agttacttct ttcaaaatgt cttcacactt
    14821 aacaatctcc tcttctatct gactagaact taaattactt atatcaggat gattgaaagt
    14881 atgatttcct atctcgtgac cttctttact tgctcttact aatggttctt tataccattt
    14941 tgcatgtttt ccagctataa aaaaagtagc ttttacattg tatttcttta atacatctaa
    15001 aacttgacta gtttctttag gatgaggacc atcatcaaag gtaattgcta ttagcttttt
    15061 ttcccttgaa ccatgtttaa tcaaaacatt tccattagta tccatcatca aagcagaaac
    15121 tttactaaaa ttagatatta acactattcc acaaaacaag actactgcta ttaagcactt
    15181 atatactgtc ttttttttcc atgatgtcat tttttaactt cctttcaaat attttagtta
    15241 tttataaaaa ttttgagtgt aatatgtttt atagcttcct ccaaatatta ctccaactcc
    15301 aatattatta tagttcccca aaatattttt tctatgtcct tcagagttca tccaagcttc
    15361 atgcgcatat attgcattaa tctgtcctgc tgctatgttt tctccagctg aagtatatac
    15421 tataccttct cttttcattc tgtcaaatgg agtttcattc ttcttattta catggtcaaa
    15481 aaaattatta tctctcatat cttcactatg ttttcttgaa ctcaaagttg cctgttcact
    15541 gtatctcaat gagtttaacc ctctttgatt tctaacacta tttacaaggt ctataacttc
    15601 aagttcaaaa cattttttaa gttcttcgct atcatctgga tataaatttt taaactcatc
    15661 ttcagtgctt ttatcaatta ttaaatatga acaaactcta ttttcttcat gaatatcgta
    15721 gaaaattgta atatacttac cttccttact tattatatca tattgatttt ctgagtttat
    15781 tatatatctg gtatttcctt ttctcttata ttttaatggt gtaatcttag ttctcactgt
    15841 ttgtctatct tgatttagtt ttatatcttg attttcacat gaattaatag aattactata
    15901 aagtgctact acttcatcat tttcaagtcc aaccattgca aattcttttc catattgatt
    15961 atatacatac caatcaaaac catattcact aatatcaatt ctaccaggtt tgccgatact
    16021 tgataaaaca tagcttaaat tatctcctaa gcttattttt tcaaaattct ttatatctga
    16081 ctctcctaag ttctcccctt cagtattatt tgattgtaaa ttttgacttt tttctttttt
    16141 atctttctta gaattatcat ttatatttat tttgtctaaa aattcattcc atatttcact
    16201 ttgaaaaaac ttttctttta aatcatatcc ttcttttaat aattcaggac tataaaataa
    16261 aacaataagt actactaaca ctaaagcaat taatctcttc aatatatctc tccttcttaa
    16321 aatcaatcaa aattttttaa tattgcattt attaagttaa tattgatagt gtatactaat
    16381 caatatcatt catacctatt tacagtaagt attagaaaaa agctttatct actaattaga
    16441 taaagctaca gtctcaagga aaatatttca tctaatgttc tatcaaatat agatggctta
    16501 tcaaatttcc aagtcccttc ataaaccaat tcattattta gataaaaagt tccttgccca
    16561 tgttttttac catgcataaa ttcacctata tactttttac ctttttccca tatataagtt
    16621 cccttaccat gaatcaaatt attcttccat tctccttcat aaagtacttc ccctttacta
    16681 ttatagcaaa taccgtaccc ttccatcttt ccacctttaa attcacctgc atatatacat
    16741 ccatcactcc acttataaat accttttcca tctttttttc cgtttttcca agttccaata
    16801 tattcatctt tactactata taacatattt ccaataccgc tcatcatatc ttcctcaaaa
    16861 taacctatat attcatttcc atttgaaaat ataaagtttc cttttccatt ttttttatct
    16921 tctttaaatt ctcctatgta ctccataact gttccttcat ctacaaaaaa agtatatgag
    16981 cctttcccct ccatctttcc ctctaagaat ttccctacat atacatcccc atttgaaaat
    17041 ttatagattt tattttttgg tttttttgta tcgacatcat ctatatcgcg tattgttttt
    17101 ccttccaatt ctaatacttc attttctgga gcaaaatcgc ccctttttaa aacacgtttc
    17161 ttcatgttct ttatacttct aatctctttg tttacttcat ttatatattt caaataatta
    17221 tcatacaaat taacatattc tttagataaa ttcataatgc cattcctcca acgttattcc
    17281 tagatatttt actaaatcta ttaaatttat tatatcctaa tagtggtcat gttttctaca
    17341 tattaagtaa ttttttcaat tttaatttta aaatgatatc ttttaaagtg atacacaaat
    17401 cattaataaa acctttattt tcgtatacta aatttaaata agctgagaga tataatatac
    17461 aaatttacat tataaactcc cagcttgtaa aattttctat aaatcttttg ctttaaaccc
    17521 tcttcctttt acttctgtaa catcatttac agatataaag gcctttttat catacttcaa
    17581 agctatatct tttatctttg gtatctcatt tgatgaaact attgtatata taatcttctt
    17641 tttttgatga gtgtatgcac cttctgcatc taaaaaagtt acacctctaa ctaaactctt
    17701 cattatatct tctgctatta aatcgacttc atttgacatt accataacag atttttggta
    17761 attcattgca tctttaataa aactcattga atacgcattt agaaatagac ctataagagt
    17821 gtataatgct aaatccaacc caaataaaaa acttcctgta agtactatca agccatttat
    17881 tgctaaagca gtgtctttca tttctatatt cttcttaatt tttagtattg cagctattat
    17941 atctgtacca ccttgagaag acctagttct aaatacaact ccgactccta aaccagataa
    18001 tataccacca tatacacttt gaagcaatat atcatgtata ggtataatat tacttatttc
    18061 ctgagttgct cctaataata atgaaaatac aatcatattt accaaacttg aaatacaaaa
    18121 ctctttttca aggtatatga accctaagat aaatattgga atattgatta aaaatgttaa
    18181 taaacctaca tttatatttg tcaaatagtt tatagatgtt gctatacctg tagcacctcc
    18241 actaagtaga tgtgctggtc ttaagaaccc atttattcct atagatgtca tcaacatccc
    18301 aaatagcatt gttgaatatc ttaaaactgg atgtttttgt agggtattct taacttcact
    18361 catttctttc tcccttcaat ctttctaaat ctttagaatt ttaaaagctt actcttacat
    18421 atattattcc tgatgtaata gataatattt caaataaatt ttttttataa tttcttgaac
    18481 tgtcatctat tacatcatct attatattat ctttttcata tatgtctagt gcaatctttt
    18541 atattctaat ctttaaaaac gttcaaatca tctcatttat gccttaaatg aaactttttc
    18601 tagcataata tgatactgct tattatttaa cttgcaatat agtaaattta tagtattttt
    18661 ttctaaatat ctattttcgc agtaatttat tttattttag caaattcaag tttagtaatt
    18721 gtctctttat aattaattcc taaatgaaat ttttcttttt ataatttcag tacatgattt
    18781 ttttatttca ttatttgcat ttttttcgtt cagtttttat tttaaatttt ttttatttta
    18841 ttttgtttta agtattcaag ttactcgtct taattttatt ttttatataa aattcattat
    18901 aattggaatt agtattactg taattgtacc agagactcca atagaaacac cactcatagc
    18961 tccttctatt tctccaagtt caaaagcctt tgtagttcct aaagcatgtg cagatgttcc
    19021 aagagcaatt cctttagcaa ctggatgatt tatattcccc agtttgaata ctgtagaagc
    19081 aaccatacca ccaaaaatac ctgtaaaaat tatggctaca actgttattg attctacacc
    19141 atttaaagaa tttgctaaag atattcccat tggtgttgtt atagattttg gaattagtga
    19201 atttattata cttacatctg aattagctat tttgccaatt atcaatacag atacaaaaga
    19261 aatcactata ccacaaccta ttcctacaat aatctcaaac atatgctttt taaataattc
    19321 aaattgttta taaagtggaa ctgcaagtac tactgtgaca ggacctaaaa agaaatttag
    19381 actatcagct cctatcttgt aattctcata agggatttta gatatgctta aaaacaatat
    19441 tattcctacg attgcaatta ataaagggtt acatatagga ttacttgttt ttcgttgaat
    19501 gtatcttcct aaattgaaaa aaactattgt tactattata ccaaatactg gtgtctgtaa
    19561 tacattatac atttttttgt ccttcttcct tcttttttat cattttctcc acaataattc
    19621 cagtagtata cattactatt agtgtactta aacatatgac taataaaagc actaatacat
    19681 tttcccttat taggtctaat gactttataa gtgatacacc tgctggaata aaaaatatag
    19741 ccatattatc gaggaaaaat ccacttacat tttctatact actcaagtct aaaactttaa
    19801 attgtagtag tagaaataat aatagcatac caactatact cccaggaata agtataattc
    19861 cttgtataaa ggaacttata tactctccta ttacccagat agataaaatt attaccaatt
    19921 gattgaaaac tttcattttc cacctccaaa aattaaagag attgcttcaa atcatatatt
    19981 tgtagtttta tcaacaagca aatatctttc tttaaaatag aaagttataa tttgacacaa
    20041 tctcttttta aatttatttt tattttaatt taataaaata catacttggt tgtttcaaaa
    20101 aacttaacta tataaaccta tttttcactt aaaatttctt ttatttttga attgttatac
    20161 atactgtctg gaacttcact tctcaaacta taaaaagtct gttgtgcatt ttttaaatcg
    20221 ccattatcat aataaagcat acccaactcg taatatgaat catcataata ctggtcattt
    20281 ttagtataag tatttatata ttttttgtaa tattttatag cttcatcctt atttcctaat
    20341 aatttatttg ttattgctaa ttgatatatt gactcagaaa tatatttttt agttttacca
    20401 gaagaaacta cacttttaaa attatctatg gctttttcat attctttgtt tttctttaaa
    20461 tttagagctt gataatataa atcttcctca tcagctacag ttatctctct ttctggttct
    20521 ttatttttaa cctcatttaa ttccttattc gttttttcta attttttact cgtttctcct
    20581 aactttttat cagtttcact taacttttcc tctttactac ttatttggtt attcaagttt
    20641 tctattctct ttttgctttg aatcaaatat atccccatac ctattaaaac acagccaact
    20701 ataatatatg gcaaaatact tttctttctt tttacttttt ttatttcttc ctttttactt
    20761 gtatcttctt tttcttcttc atttttttca aatacaggat tatctttatc tagctcttta
    20821 agtttgtcta aatatccttc tctctttttt acattaccta gtttatcata taacaaagat
    20881 aaaattacat atggctctat tagttcaggt tcttcttcaa ttatgttctc taaaatatgt
    20941 attgactcat aatttaattc ttcatttata aatcttatag aatgattgta tcttcctaaa
    21001 aaagttttaa aatcttcaga tgaaattaga tttacatatt ttctagatat atgattattt
    21061 tcataacata aagcagtata aaaactctca aatgatttag caaaatcaca ttttaataat
    21121 tttaaaagac ctctaagatt tagtatatca atgtctttag gatttatctc cagagcttta
    21181 ttaaccatat taatggcact agttatataa tttttatatg ctaaatccaa tgcattgtta
    21241 tatcttttat atgattctaa ttttaactcc ttagacgttg tatctgactt tgaatttaaa
    21301 gctccttgca agtttaatag agtttcttct ttataatttg tagtcacata actctgtttt
    21361 aatgctttta atgtttcatc accgtcttct tcttctatat taaaaaaagt caaatcactt
    21421 ttattatctt ctatcaaaga tatatctaaa atttttctag gcatgctttc tatgtcttgt
    21481 tttatatctt taactaaaat aatactcacc tccactctaa aatatatatt taagataaca
    21541 tatttaatat gtcaagtcaa aactatacat atttttccac cattctcata ataaaaaagg
    21601 taatcctctt cttttcataa aaaggttacc tctttttcaa tactattaac ttttaatgtt
    21661 gaattttttt acttttctat agagtgtagc tatacctata tttaatgcct cagctacttt
    21721 tttcatacct tctgtattac ttccatattt ctttatggca ttttctatag cttccctctc
    21781 aaggtcatct atagtcttaa cttcttgttt ataaagttca tctagtttaa aagatattaa
    21841 atcagacata ctccttacaa aagcagttaa ctccttatct tttgaaagta tcttttcttt
    21901 ttgttcttca ttaaacgcag ctatacccaa gattccaagt atatgctctc ccattttaac
    21961 gggagtacat atatcagcta actctttaca attttctcta tttgcacatt tattacagtt
    22021 ctcttctatt tctttattta taacatagga tttcccatct tttaaaacaa gagagtacac
    22081 tgacttctct gatattgtct ctcctatttt acctctgaat attcctgtac ctgctatcct
    22141 agttaaatct tttgtaacta aagtaacatc tacatccaag acattagaaa tattctcgca
    22201 aatactttga acgtaattcg ttatattatt taaattcaaa gtaatccctc ctatttagat
    22261 ttatattttt tattactcta cataaatcct attcttgaga actttaagct tgcggttgtg
    22321 gttgtgtctc attaggctta ttatcagttg gtggtgtttc tggtttttgt tgattatttg
    22381 ggttttgatt gtttgtattt tgattattct tattttcgtc tgtatttggt ttttcctctg
    22441 gttttggttc catagtccca actaatataa taccttcctt cttaggataa tatgaattag
    22501 ctattttttc agttttaatt tttttaccat ttgcatcatt aaatgttcta tatgttgata
    22561 cagaatatgc atttcttcca cttttgtcta ctttttcttt acctttaggc attgtagggt
    22621 cattaactct tttcattgta gtttgtgaaa cgccatctaa ttttgttgat attgttatat
    22681 tttgtttatc ttctgcactt ccatatatat tgcaaacaat ttgatttcct gaaacgtaat
    22741 tttttatgta aactggatgc tttagattat ttttaaataa gaaatctatt ccactatctg
    22801 caacagttgc atctcttcct tttggaacat aacttgatgg tatagtatga ttttttacat
    22861 taacaatttc taaacctgcg tatagcacag aattgtataa cgtagatgaa acttgacaaa
    22921 ctcctccacc ataatcttct tccatctcac cttccattat tacaggtgca cttttatatc
    22981 cattttcctt acttcttttc cctgtatgtt tattaaatga gaaagtttct cctggcataa
    23041 gtaatacatt acttatatta tctgttgcta attttatgtt tatacttcta tttatttgag
    23101 aagttttaaa tgttgttgaa tacgtaccta aatttgtatc tatattagca agttgctctt
    23161 tttttacttt tgctggagta gcttttacta ctaactcatt tttatagtta ccttttttag
    23221 tttgattatc aaaattctcc atactcttag aaatatccat tttaagacca tcagaatctg
    23281 gtataacctt gactttttca ccacttatat caagtgtagc atcttttaca tctacatcta
    23341 tttctttagc tatcttttcc atttctgctt ttaatttatt tttatcataa tttatcgcaa
    23401 ctactaagtt gctttttttg ccaaaatttg ctgaaatagt ttttgataga ttgccaaaga
    23461 aagcactctt tctatttaaa ttatatgcgt tttctactgt tttatccagg tcagtagata
    23521 aatttaaatc tttgctcttt actttccagc ttttatcatt gtaattaaaa tcaacattct
    23581 ctaatttgta ttttttagct aattcctgtt ttgcttgtga tttagttaat tttccaatat
    23641 ttactccatt aacatatgtg ttttttgcta ttttctcccc tttaaattgc atgcacatta
    23701 tgcctataaa aattattact actaatgcta cagctccaat agctataact agctttttgt
    23761 tcacattact catcccatac ttctccttac aataaaatta tttatatatc cctattatta
    23821 tattactaca taatgcgcct taaaacccca aaaacttttt aattatatat taatttaata
    23881 ttattaatta atattcattt agtccatttt ctgatatggc atatattttt tcattgtaaa
    23941 tattaatagc ataaacttct ttgcctctaa ataagccttt atttactaca gcataataat
    24001 aaatattttt atattttcca aacaattctt ctaaactctt tttacttttt acatatctat
    24061 ctgctttctc tatatctaat atctcaatct ttttatactt attttctttt tcatcaagag
    24121 tattagttaa cacaaactta gctttatctt ttgtaatacc aaattgataa cttccatctt
    24181 ctaatattct aaagtatcca tcaccataat ctactttgta atctttttta ccatctttat
    24241 atgaatataa atctttagtt tttgcactta ccaaaacttc atttattaat ttatcatact
    24301 catatacttc agcataatag tatttattat tttttatcat ttgtggaagt gaatttatag
    24361 atagatttgc cttgtctttg ccactttttt tagctattac atttataatg tcatcagatg
    24421 ttaaagtata caatgataaa ttctttttat attttttttc taaactctgt accttttcat
    24481 catctgaata atcgtctttt aaatactcaa tatattgtaa tgctctttca taatctccag
    24541 aagtatttgc ctcttcagct ctacttatat agtaatcata catttcttca atacattgtt
    24601 ctttcccatt ttgagccata ctgtaatact tttcatcttc ttttaatact ttattatact
    24661 tttcaatagc ttcataatac ttatatgctt tttggtcttt tactgctgag tcataaacat
    24721 ctctagactc tttgattgtt tctatattct gtttgtatac atctaggtta ctacccatac
    24781 catttaatat tgaaacagta cttatgtagt taatggcaat atcataagta gtattttctt
    24841 ctttatacat ttctctaact ctatcagctt gagctaataa gtcatccaca tctatactta
    24901 ttttgtttaa ttctttcacg gtatttatta atccaataaa actttcttga cttatgtctc
    24961 catctaaata tttatcacca ctatttaata gcaatttatt tattttttta gaaacagact
    25021 tattaaacct ttccattttt gaatcagaaa actttttttc tatacttgtg tagtaatcaa
    25081 cagctataga atactgtctt ttctttataa tctttaacaa ctcattagct tcatttccta
    25141 cactaaactc gttactactt aagaaaaata ctattatcaa agcaattaca cctaatgttg
    25201 ataatgaaat cgcaactata gatttccttt tttcatcaat aaaatctaca gccttctcaa
    25261 ataaatctct aaaattcatt atagttccct ctccatttaa taatctttat attttatggt
    25321 aaactaaatt tcttattggt tattatatca taattcttga aaaaaaataa aaacacaagt
    25381 taaatcgtgt ttttatttta cctatcaatc attattttat acataaatat ttcctttaca
    25441 taaattatga tatctttctt tttatatccc tagaatgact cttttgtttt ttattattac
    25501 tgacagtttt cgttcttgtc ttgtgtatag ctttgctatc aaatattttt ctagcattgc
    25561 ataaaacaat tccaattgtt aaacaaactg taagcacact tcccatcaaa aagtaataat
    25621 ccaatcctat atgtactccc ataactgaat ttattaacac taatgcaaaa gtcattgcaa
    25681 aacatatcat catggagata actaaaattc ttagaatttt tttcaatcca ctcacctcgt
    25741 ataatcacta aaattgacac taccccttat ccattactat accaaattag taaaaaaata
    25801 gcaattacta ttgtcattta tattaggaaa atattaaatc tttttaataa atatcttttt
    25861 ttgacataag gattacttaa cttttaataa aatagtaaca ctaatatgta ttaattaata
    25921 gaataaaata aatgataatt tattgagggg tgatttacat gccaaatttg ccaagtttag
    25981 ggtcaaaggc tcctgatttt aaagccaata caacaaatgg tcctattaga ctctctgact
    26041 ataagggtaa ttggattgtt ttattttcac atcctggtga ttttacacca gtttgtacta
    26101 cagaattttt atgttttgct aaatattatg acgaatttaa aaaaagaaat acagaactaa
    26161 ttggtctaag tgttgatagt aacagttcac atttagcttg gatgtataat atttctttac
    26221 ttacaggtgt agaaattcca tttcctatta tagaagatag agatatgaga attgccaagt
    26281 tatacggcat gatatcaaaa ccaatgagtg atacatcaac tgttcgctct gtatttatta
    26341 tagataataa tcaaattcta agaacgattc tttattatcc actaactaca ggaagaaata
    26401 ttccagaaat acttagaata gtagatgcac ttcagactag tgatagagat aatatagtta
    26461 ctcctgcaaa ctggtttcct ggaatgccag tgattttacc ttatcctaaa aactataagg
    26521 aattaaaaaa tagagttaac agttgtaata agaaatattc atgtatggac tggtacttat
    26581 gttttgtacc agataattat aatgatgaag aagtgagcaa gaaaattgat aatacttgta
    26641 gctggaaaaa agaacatact aaaaacattg aaaatgaatg taactgtgaa catgaacatc
    26701 atgactacct gaacaaagct cttgactgta aacaagaaca caagactgat attaaagatg
    26761 attgcaatca tgagaaaaaa catactaaaa atactaacaa agttcacaac tccaaacaag
    26821 ataagtttaa agataagtct tgtgatgaaa tgaattttaa ctatgataaa gatgaatctt
    26881 gtgacaaaat aaattctagc tataacaaag aagatagtag ttatgaagat ttctataaac
    26941 ataattataa aaactacgat tatactagcg aaaaaaatac taaaaaaata gctatgaaaa
    27001 ctttaaaaga ttctaaaaaa ttagttagac cacaaataac agacccatac aatccaatag
    27061 ttgaaaatgc aaactgtcca gatataaatc caattgtagc agaatatgtt cttggaaatc
    27121 caactaatgt agatgctcaa ctattagatg cagttatatt tgcttttgct gagatagacc
    27181 agtctggaaa tttgtttatt ccttatccta gatttttaaa tcaattactt gctcttaaag
    27241 gtgaaaaacc tagcttaaaa gtaattgtag ctattggagg ttggggagct gaaggattct
    27301 ctgatgcagc attaacacct acatctagat ataattttgc aagacaggtc aatcagatga
    27361 taaatgaata tgctttagat ggaatagata tagactggga atatcctgga agtagtgcat
    27421 ctggaataac atcaagacct caagatagag aaaactttac actcttacta actgccataa
    27481 gagatgttat aggagatgat aaatggctta gtgtagctgg aacaggagat agaggatata
    27541 taaattcaag tgctgaaata gataaaatag ctcctataat agattatttt aatcttatga
    27601 gttatgattt tacagcaggt gaaacaggcc caaatggtag aaaacatcaa gcaaatcttt
    27661 ttgattcaga cttatctttg ccaggatata gtgttgatgc aatggtaaga aatcttgaga
    27721 atgctggaat gccttctgaa aaaatccttc ttggtatacc attttatgga agattaggtg
    27781 ctactataac aagaacttat gatgagctta gaagggatta tataaataaa aatggatatg
    27841 aatatagatt tgataatact gctcaagttc cgtatttagt taaggatgga gattttgcaa
    27901 tgtcatatga tgatgcttta tcaatattct taaaaactca atatgttctt agaaattgtc
    27961 taggtggtgt attctcatgg acatcaactt atgaccaagc aaatatactg gctagaacca
    28021 tgtctattgg tataaatgac cctgaagtat taaaagaaga acttgaaggt atttatgggc
    28081 aattctaata gaatgtagta aaattttata gttatataaa aagcagattt tattatatta
    28141 aataagttgt atctaattaa tactattatt aattgtttat aaattagata cttatttttt
    28201 cataatacaa tctgcttttt taatcaaaat ttatttaatt acaagttgtt taattataaa
    28261 gtaggaattt agatatactc ttataccatg taattatgta taaatatttt tttattatac
    28321 accaatagct tttttagcta atttatcagc ttcctcatta tacttatttc cagaatgagc
    28381 tttaaccttt gtaaatttta cattaagctt attcttaata ctgtcataga aatttttata
    28441 tgctatagtt ccttctttat ttgttttcca aactccagta caccactttt caatcccttc
    28501 atagtcaaag tataaaatca agttttgaac attattgtca atacagtact gcattgcaat
    28561 tttagaagcc tctatctctc cagctacatt tctcatactt actaaagttt tctcttttcc
    28621 tttttcacta taagttttta taacttcatt attttttaaa atcacaacac ccgaaccata
    28681 catttttact gaatgttcat aacttccatc tacatatgct tctataaact ccttatcttc
    28741 ttgaaaactc aatttttctg acccatcaat atattcttta gcttcttgaa aagtagaaaa
    28801 actcttatat tcagctcctg agaatccatt tacttgtttt ttgcactcat cccatgtatt
    28861 atatacacct atatttttac cttttttcac agcataaaac ttttgttttg ccaaatatat
    28921 cactcccact cttaattttt atcttcttct ctcataaata tatctaaatt tataagatag
    28981 tttctatcaa aatattttac tttcatatct ttttttataa tatcaatatg gtacacttct
    29041 ccttttacag ctctttgtct tatattttca tttatatctt tttttataat atccttatca
    29101 acatcattgt tatccatttt agcatcaaca ttcaacgctt ttatagtatc aaatataaca
    29161 gattttagta ttaaacttct agatttattt aaatgtcgcc ttatataagt ataaaactca
    29221 ttgctattaa cctttgaaat tttacaatcg tgtaaatctt tctctaatct ctttaacaca
    29281 cttatattag ttcctacatc aaaaatcaca aaacatccat agtcatattt gcttcttaaa
    29341 attctcccca tagcttgctt tacctttatg gtcatttgag gataatttat agtatagtag
    29401 tctataccat acttcttcat tatagtaaaa tacaaagggt ctttaggatt tagattcgga
    29461 agcttgtcta aagttacaca aaccaaacca tcccctggaa tgtctacgcc ttcaaaacat
    29521 ccttttgagc caagtactac acattttcta tttaaatcgt taaggtgtct aatgcccttt
    29581 ttatcagcat aaatttctaa gttaaaacta tgtaagtatt ttttcaatat ttcataagtt
    29641 ttttcttgtc tatctttact attaaaaaga gctaatgtat gaccttctgt aatctttgat
    29701 atattagata taattttact catctcattt ggaaattcag aatttctgta ctcacaaata
    29761 tcagaaaatc caactacaga gactctattt ttataatcaa aaattggttc tataatcttt
    29821 tccacattct taactctgtc tattcctaat gtatttttaa aataagacat actttcagat
    29881 aaactcaaag ttgctgataa aaatattcct ttttctaatt gagataaaat attttcttca
    29941 aataaatctg ctatttttaa tggtactact cgaaattcaa agtcattata attcttatca
    30001 atttcaacta tccttgcata atcatccttt tcatcatact ctaaaaagat ttcaaatata
    30061 atctttatat cctctaaatc tcttgtcttt gcctttccaa atttatatat atctgcttct
    30121 ttatctatac tatcatcatc aatattccta taaattatta ttattattga aactaaattt
    30181 tttattattt tctcacaact caactttatc ttttcactat aggctctata acttatttca
    30241 gtatctatac catctttttt tagttttccc acaatttcat ctatttgcaa attcagttcc
    30301 catcttaaat tataattact tacattatta tattcattac aattaccaaa ctttaatatt
    30361 gaatctatct cttcaataat gaaatttata cttctagcaa ttttttgttt atcttctctt
    30421 ccaattttta atacattata aaatttatca aaagccttta tttttctcat atttctacta
    30481 tattttttat atataaagct actattttga ataaactcgt aaggataaat ttcttgtaat
    30541 aagtacctta aagactttga atttataata cttgaaaaga aatcatatcc tttttcagtc
    30601 aaattatgtg cttcatctac tattatattt tctaaaggtt tttcatcctt atacggccat
    30661 ttagctaata gtgaatgatt tactactgtt atatgttctt cttttaattc ttctattctg
    30721 tttttatata aacaatcttt tttgcatttt ttaggtctgc acatatttgg gtcacaactt
    30781 acatttctta agtgagtact tatttccttg aagttgtcaa acactaaata atttatttct
    30841 tctatatctc catacttgcc accttcaact aatctcttca aaaatattaa agataaaatt
    30901 tctcctttag tagggttttg agactcataa tcatctatat atgcttccag tctatctata
    30961 caaatatagt tattttttcc ctttatatat ccgtaactta cttttccatt tagacccaaa
    31021 gaatctaaca catttggaat atctttattt attaattgta tctgcaattc ctttgtgtca
    31081 gtagaaatta ataatctttt tttattaatt ctagcctcta atattgcagg caataaatat
    31141 cctacacttt tacctatacc agttggtgcc tctatacatg caattttttc ttcatcttcg
    31201 ctatttctaa acaactctct tattgtttta gtaagctcat attgaccagg tctatattca
    31261 tatgtaaatc cttctttatt ctcccaaata gttttgtatt ttaataattc ttcataattt
    31321 ttttcttctt catttaaaat ttttaaggtt tctctttcct tcttcttttc ttcttttgag
    31381 tcaaatatat tatattcttt ttttatattt atattatttg ataaatcata atttgcctct
    31441 tctaaaaatt tgctccattc ccatgttgga agattaaatt ttttaagata tgaatttatt
    31501 ttaaaactca atggctccaa agtagttttt tcatagttat taaattttac taaaaggcaa
    31561 tttacaatat ttattatatc aatagcatct gataaagctc tattttccac tttagaatta
    31621 caatttgtta aagtattttt taagtattct aagctataat ctttatgata tggttctaaa
    31681 ataactgcta attcaattaa atcaataaat ttatttttta actttggcat atgatactca
    31741 aaaaactttt ttttcagact taaatcatga catataatga aactatcttc tacaaaattt
    31801 acaagtctat cttccaccag ttctatttta ttagctattt ctaaatcatt tttatctaaa
    31861 tttttacata ctgagaatac ttctataggt acctcaaatt tgttttttat taatgattca
    31921 taggtatata ttttccagtc tttaaccttg acagctccaa cttctaaaat ttctgaattt
    31981 aaacaatcta atccactaac ttctatatct aaaaaaacaa catcattcaa tacacttatt
    32041 atattatcca tttttatatc ccttcaagtt aaaccagcct aacttattta caatcatttc
    32101 tctttatatt ttatcattta tatacacttt atttaagata attaatatca actttatatc
    32161 ttacagtaaa cttctttcat ttattatttg tatatgtgaa tatttttaac tataaatatt
    32221 caaactatat tataagaaat atactttaaa ttttaaataa gaggtgaaat tgtgaaaaaa
    32281 gatagcctaa aaaaatacat tatgatagga gcatttgctc taacactttt tggaattgct
    32341 agtataaatt ttaaatcatt agataaaaca aaaactcaaa tttctagtcc aacactcgac
    32401 acacatgaat atgattggta ttttaaccct agggaagatg gtaaacagcc atcacctata
    32461 aaagaagctg atttttttaa aaaatacgga gcttattatg taggaaatcc caatgaaaaa
    32521 gttatatatc tatcatttga tgctggatat gaaagtggaa acactccaaa attattagat
    32581 acgcttaaaa aacacaatgc taaagctcaa tttttcgtag ttgaaagtta tataaaaagc
    32641 aatccagagt taataaagcg tatggaaaaa gaaggacatt tagtttgtaa tcattcaaaa
    32701 agccatccat caatggcagg tattacagat tttgaaaaat tcaaagaaga aattacaagt
    32761 gtagaaaaag catacaaaga tgttactgga aaagaaatgc ctaagtattt tagacctcca
    32821 atgggtaaat ttagcgaaca atctttaaaa tatacacaag atttaggata taaatcaata
    32881 ttttggagtt ttgcttatgt agattggtat gaaaagaaac aacctactca tgaatttgcc
    32941 aaaaacaaaa tttattcaag aactcatcct ggtgcaatag ttttactgca tccaaattca
    33001 tcaacaaata ctgagatatt agatgaggtt cttacacatt gggaaaaaga aggttataaa
    33061 cttaaaacac ttgattattt aaataataaa aaatagtatc ataaatttaa aaaaactcta
    33121 tcatgaatta tagtaaaaat atagttattt ataaatactt taattctcga tagagttttt
    33181 tattttttat agctatttaa aaagaattgt ccattcattt atctctttgt atcctatatt
    33241 atgatatatt ttacctgcta catcattatt ataaaaaaga catggaactt ttccttctaa
    33301 caacaattct ttactcaaat tgtaaaccat ataacttgca agtccttttc ccctatatct
    33361 tttatctgta cttacagaga ccaccattgc caaaaaacta gtttccatac cagttgacac
    33421 agtgctaatc atagtatcat catttctaat aaaatatgct cttacatttc cctcttttaa
    33481 atgaactttt ctttcttcta tgtaattttt acttacttta tagtctgacc tatttaaaag
    33541 ttttcctatt tcatcaatat ctttttcctg agcattttct attttatact ccttcatgtt
    33601 ggaaaaatct atttctttta tttcttttaa tacacaaaat ttattatcta gtttttcata
    33661 aaaatctttg tatttactta ttagtctatc tattacacat ttttttccac ttatgctttc
    33721 tacatctaaa tcttttatat gattcttcat ttctcctata ttaaaattat ttttaaaact
    33781 ataaattata agtgttgact tattttttaa tattatagag gttatatttc caccttctac
    33841 ctgagaccat atatcttgat attgagagct aaatccataa ttctcaacgt atccaattat
    33901 gaataaattt aaactttctt catgtgatac atattgccaa aattcttttt ctaaagtatt
    33961 atctattttt acaatcaagc agatatcctc cttctatgtt aataatgata taccttataa
    34021 tttatagtat catttaaaat cattatattc taccaaatat tctaaatttt taaatatcta
    34081 tgcaatatgt tcgtatttat ttttatattc tgttactgct tcactccaag cttcttctac
    34141 tgaaatacct ctcttatttg caattttttg tgctaattct attattttca tagcttttct
    34201 tgatatattc atatatattc ctcctctaaa ttatcataag ttattttaaa gttaaatttc
    34261 tatagtcatg ttatatattt atttacttat atcttactaa ttatttatgt actaaatatg
    34321 aactacaata gaagaaattt agaacttaat aaaacataaa atttatatac agttcatata
    34381 tatttgtcat atcacaagac aagtgatata atttattatc attttactgg gggtgatatg
    34441 ctatgaaaat aagagctgaa tatacatgtc ctcttgaaat tgtacatgac ataatcaaag
    34501 gaaaatggaa aactatcctt atatttgaat taagacaatc taataaaaca ttttctgaat
    34561 tgcaacataa tatttatgga ataaatcaaa aaatgttgat tcaacaatta aaagagttac
    34621 gtgattttgg gattattgat aaaataagtt ctgctggata tccattacat gttgaatatt
    34681 ttcttactaa tcgtggtaaa aaaatgttaa aagcagtgga aataatgcaa gaaataggaa
    34741 tcgaatatat gcttgaacat ggtcaacaag aaattctaga taataaagga atttgctaca
    34801 ataagtaatc ctatacatac caaaaagtaa gtaatttaca ttttttacaa tagtattata
    34861 ataaaaataa ataggaggta taatcatgtc tatagcttta atattgattg atattcaaaa
    34921 tgattatttt aaaaatggaa aatgtgaatt atttcaatca gaagaaactg ctgaaaatgc
    34981 taaaaaaata ctactgtttt ttagaaaaaa caatttacca gttattcata tacagcatat
    35041 atcaacagat aaaacagctt ctttttttct tcctaatact catggttcag aaataaataa
    35101 aattgttttt ccactagata atgaagaaat tataattaaa cacacaccag atagtttctt
    35161 tgaaacagat ttgcaaagta tccttgagaa aaaaaatatt actaatctag taatctgtgg
    35221 aatgatgagc catatgtgta ttgatacaag tgtaagaaca gcaaagaaac ttcgatacga
    35281 cataactcta ataagcgatg catgtacaac gaagaattta tcttggaata atatagaaat
    35341 taatgcaaat actgtacatc aagtattcat ggcatcacta cagaacagtt ttgcagatgt
    35401 aaaaaacaca gataaatttt tatctaacta ttacaaataa aaacatacac tatgttaaaa
    35461 gagcaagttt gatttattta agcttgctct ttaatcattt aaaattagat gctttctatc
    35521 atttttatat acataatata cgtttataca ttttatattc atatataact attatataaa
    35581 ttttaaactt tactatattc acataaaaaa tgtagtatta tagtatatat aatattatat
    35641 agaagggggt gctagataaa tgaaccatca tatattgatt caatttgaat atatagcaag
    35701 aatcattact gctggtttct gtggggcttt aattggatat gagagaaaga atagactaaa
    35761 agaagctgga atacgcactc attttatagt ggcattagct tcagcactta taatcattgt
    35821 ttccaagtat ggatttaatg atatagtggg tactccaggt attggtctag acccagcccg
    35881 cgttgcagca caagttgtca gtggtatagg ttttttaggt gctggattaa tatttattag
    35941 aaatcaatca gtaagtggtc ttactacagc tgctggtata tgggcaacag ccggtacagg
    36001 tcttgccatt ggctctggat tatacttagt tggtattgtt tcaagtatca ttattgttat
    36061 tgtacagata acacttcata gagataggaa atggatgaaa ctccctacag cagagcaagt
    36121 ttctcttaaa atttctaaca gcactgattc catagaatat attgaaggta aatttaaaaa
    36181 atctaatatt gaaattataa acatgaatat taaacgcctt gatggggatt ggttagaagt
    36241 agttatatat actaagttac ctaaaggata taaaaaaaca aatttattaa aattatttag
    36301 cgataatcct cttatagaaa ctttagaaat ataatataaa aattgaagct taaaaataat
    36361 aatatattta atcaaggtca atatataaat aattaaggga tgagtctata taaaattcat
    36421 cccttgtttt ttgccattca tatatatttt ttcaagatat ttttgtttat ctattatcta
    36481 gccaagtaac ccttgtgaac taaacttttt aatacaaaaa cttcaataca aaactaaata
    36541 taatttttat taaacattct atacatatag tttgtttctt gagtgaaaaa tagatttcat
    36601 attgttaaga tattgttaaa tatttcaatt ttctgacaag tatgttgaac aataacttat
    36661 cctagtgtat tattttagtt gtagaataaa actaaatcgg caaaactaga gaaatttagt
    36721 gacgcaaagc tatagggact aacgcttata aaataaacta tgagttatgt cagccagttg
    36781 ccaaaaagat attgttcttt ttgttttatg aaagtttttt agggggatag taatatatat
    36841 gtttagagat gaaatggata aatgtacaca catgttaact gcttatatta gtagtttata
    36901 tgattattgt gattttatag atacacagct agatgatttt atactagagt acggagaaaa
    36961 tgtagtagaa tcttgtttac atcaagtgat ggtattggta agtaagtata attaaataga
    37021 aattgttttc tagagaaccc tttttagttt tatctacatt taaaaatgtt attatattaa
    37081 aaaactaatc ttccatatat gcaaagtttt cttccatata acaatttctt cccatttata
    37141 ctttttcact tgtatcttta ataaaattca acttcaaaaa ttattctatt tcttatcttt
    37201 acaccaattc ctatcagtat tatcctttat ataggttcta actatttcgc cacaatctaa
    37261 acataaatct gaatatatag tagattgtac tggaaaagtt ttatttataa ctttatctaa
    37321 ttttccatct cctctatatt ttaatccaat agtttcagca tatatgccac cagttgttaa
    37381 aattcccttt tcaatattta cacttccaca attagaacat ttcacattta taacccccta
    37441 aacaattatt ttttcatgct atcttataat ttaaaatata atttgctacc gattttataa
    37501 cacagtggca aatcggtgcc aaatcaacat tttttcattc tatttaccat ctaatccatt
    37561 gaaatataga tatttagtta taggaacttg aatttctgtt acaaactcct ctacaattcc
    37621 agtctcatgt atatctatct tatagatttc tatagggtca gcaattatct tataattatt
    37681 ttcttctata aatttaaaca ccttctccat atacatctta ttattagaat tactcccagt
    37741 ataatttaaa gttacataat atccttcatc aaaaactata ttatatactt tctcattact
    37801 ttccagaaaa caaaatacag atttaaactc attaaatatg cctttattaa ttgcttcagt
    37861 agaaaaggca gaaccaatat tgttgtttcc aagtatatta aatctatctt catattcttt
    37921 ctgaagtttt tgaattaaaa aatcgaagtc ttcatccctc tttatatcag catttaattc
    37981 taaagctttt cttttttcta tatatacaac ctctatctca tctatttttg tattttgaat
    38041 tacactttca attgaactca atctttttat aatattttcc ttatggctta taaattcagc
    38101 tattttttta tcaattaaat cgagttcttc atttaaaata tttttcgtag actctatact
    38161 tctgtcatct aggtattctt ttattttctt cattggaaag ttcaagcttc taaattcttt
    38221 tattaaattt aatttccata tatctgatat attatacatt ctatatccat ttatatctct
    38281 aactggtctt agaatgccta tttcttcata atacattaat gaatctctac ctattccata
    38341 tattttagat atctctccta ttttatagta atctttcatt tatataataa actcctccga
    38401 aatcttattt ttattttaaa tcaacattat tactctataa tactatagta ttagaatata
    38461 ctaaaaaaat ctttaaaaca aggataggaa aataaacatc ctaataatta attattaaaa
    38521 tatttttata ttgtaatatt aggtatagta tttataactt caactttttt ataaatatat
    38581 tttagtttta tatagtttta tgtttacagc tattatatcc atctctatgt aatatttttc
    38641 atattaaaac tgatttctat agattaatag tttataaatt tagtaaatga atatttatta
    38701 tagtctttaa caaaaaatac aagaataaac ttaattttaa taactaaaat ta
//
LOCUS       DAYAKB010000032        38152 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.032, whole genome shotgun sequence.
ACCESSION   DAYAKB010000032 DAYAKB010000000
VERSION     DAYAKB010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38152
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.032"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(129..740)
                     /locus_tag="ACGI3L_001965"
     CDS             complement(129..740)
                     /locus_tag="ACGI3L_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9197674.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(832..1821)
                     /locus_tag="ACGI3L_001966"
     CDS             complement(832..1821)
                     /locus_tag="ACGI3L_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFG9197675.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1888..2751)
                     /locus_tag="ACGI3L_001967"
     CDS             complement(1888..2751)
                     /locus_tag="ACGI3L_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HFG9197676.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2857..3453)
                     /locus_tag="ACGI3L_001968"
     CDS             complement(2857..3453)
                     /locus_tag="ACGI3L_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheB methylesterase domain-containing protein"
                     /protein_id="HFG9197677.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3493..4296)
                     /locus_tag="ACGI3L_001969"
     CDS             complement(3493..4296)
                     /locus_tag="ACGI3L_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008983 - protein-glutamate
                     O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HFG9197678.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDRTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4332..4772)
                     /locus_tag="ACGI3L_001970"
     CDS             complement(4332..4772)
                     /locus_tag="ACGI3L_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFG9197679.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4785..6887)
                     /locus_tag="ACGI3L_001971"
     CDS             complement(4785..6887)
                     /locus_tag="ACGI3L_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFG9197680.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7148..8851)
                     /locus_tag="ACGI3L_001972"
     CDS             complement(7148..8851)
                     /locus_tag="ACGI3L_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HFG9197681.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8877..9836)
                     /locus_tag="ACGI3L_001973"
     CDS             complement(8877..9836)
                     /locus_tag="ACGI3L_001973"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9197682.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9972..10490)
                     /locus_tag="ACGI3L_001974"
     CDS             complement(9972..10490)
                     /locus_tag="ACGI3L_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFG9197683.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10533..11018)
                     /locus_tag="ACGI3L_001975"
     CDS             complement(10533..11018)
                     /locus_tag="ACGI3L_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HFG9197684.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(11015..11662)
                     /locus_tag="ACGI3L_001976"
     CDS             complement(11015..11662)
                     /locus_tag="ACGI3L_001976"
                     /inference="COORDINATES: protein motif:HMM:NF016398.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HFG9197685.1"
                     /translation="MNAIIKGGVYIINYLELDDVHIDALREIGNIGSGNAITALASMI
                     NSNVEVLIPMVKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLML
                     SSLFNKEEAFLDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVG
                     AVLNVPMIRFSDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11697..12059)
                     /locus_tag="ACGI3L_001977"
     CDS             complement(11697..12059)
                     /locus_tag="ACGI3L_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9197686.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(12803..13300)
                     /locus_tag="ACGI3L_001978"
     CDS             complement(12803..13300)
                     /locus_tag="ACGI3L_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9197687.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(13475..14386)
                     /locus_tag="ACGI3L_001979"
     CDS             complement(13475..14386)
                     /locus_tag="ACGI3L_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197688.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15310..16161
                     /locus_tag="ACGI3L_001980"
     CDS             15310..16161
                     /locus_tag="ACGI3L_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HFG9197689.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16165..16635
                     /locus_tag="ACGI3L_001981"
     CDS             16165..16635
                     /locus_tag="ACGI3L_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197690.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16648..17958
                     /locus_tag="ACGI3L_001982"
     CDS             16648..17958
                     /locus_tag="ACGI3L_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9197691.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            18170..18916
                     /locus_tag="ACGI3L_001983"
     CDS             18170..18916
                     /locus_tag="ACGI3L_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9197692.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTDDSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19278..20819
                     /locus_tag="ACGI3L_001984"
     CDS             19278..20819
                     /locus_tag="ACGI3L_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HFG9197693.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKASISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20854..21960
                     /locus_tag="ACGI3L_001985"
     CDS             20854..21960
                     /locus_tag="ACGI3L_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9197694.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFQGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGEIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22339..23625)
                     /locus_tag="ACGI3L_001986"
     CDS             complement(22339..23625)
                     /locus_tag="ACGI3L_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFG9197695.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23748..26846)
                     /locus_tag="ACGI3L_001987"
     CDS             complement(23748..26846)
                     /locus_tag="ACGI3L_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9197696.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVTLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27572..27730
                     /locus_tag="ACGI3L_001988"
     CDS             27572..27730
                     /locus_tag="ACGI3L_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197697.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(28017..28721)
                     /locus_tag="ACGI3L_001989"
     CDS             complement(28017..28721)
                     /locus_tag="ACGI3L_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197698.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28712..30319)
                     /locus_tag="ACGI3L_001990"
     CDS             complement(28712..30319)
                     /locus_tag="ACGI3L_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HFG9197699.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30573..31751)
                     /locus_tag="ACGI3L_001991"
     CDS             complement(30573..31751)
                     /locus_tag="ACGI3L_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197700.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(31977..32471)
                     /locus_tag="ACGI3L_001992"
     CDS             complement(31977..32471)
                     /locus_tag="ACGI3L_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9197701.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNIGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32472..33233)
                     /locus_tag="ACGI3L_001993"
     CDS             complement(32472..33233)
                     /locus_tag="ACGI3L_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9197702.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33935..36769
                     /locus_tag="ACGI3L_001994"
     CDS             33935..36769
                     /locus_tag="ACGI3L_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197703.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIMHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36812..38056
                     /locus_tag="ACGI3L_001995"
     CDS             36812..38056
                     /locus_tag="ACGI3L_001995"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9197704.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
BASE COUNT        12832 a         6375 c         4426 g        14519 t
ORIGIN      
        1 ttatcaagat aaattattta taaaataaat catttataaa atataattta tactttgaaa
       61 ataaaataaa ctatcttcca aacattttat tatatgctta aaagatagtt ttgtgtcttt
      121 aaaataaatt aaattgtata tattccttca cataactttt gtatattact aggtggttgc
      181 catttaccat cttttttagt atatgtaatc atagttgtaa cttccttagt tggtttctta
      241 ttgtaaaggt ctataatcat ttttgtcata tcatcttgaa cttctttttc ttttttatcg
      301 taattctttt catcagttac ataagatttt actaaagtgt tcgcttcact cattacttta
      361 ctagtatcta aagctttact tacaactttc aaagttatct tatccttact agaagattcc
      421 actgttactg tcttttcaac accttgaatt aatttaacaa ttgtttcgta tatcttttca
      481 gcattttctt taccataaag aggtgtcaat tgagcaatca ttgaaacctt gtccttgctg
      541 ttataagttt gaatctgttt atattcagct tctgttaatg catcagaaat tcctttttca
      601 tcatacttat acatttctaa tgcagctaaa ttagcttcaa aattcgactt tactttttct
      661 tctgcattag aacaccctat agttagaact aaaactagag ccataatcgt agataatatt
      721 aactttttta ccattttcat acaaacatcc tccctcaatt aaaataataa aaaatttatt
      781 tatcaacatt ataacataaa tttgtctaac tatagaatta ttttgaatat tttaccactt
      841 ccagtctatt ccaataccgt tttcttttgc tttatcgtat attctttttg ctgttacgac
      901 atcttgtaca cctatcccaa cagttttaaa tacaattatc tcatcatcat cttctcttcc
      961 aggaatagtt ccgtttataa catttcctaa atcaccacta aaatcatctt tacttatctt
     1021 accttctttt aatggaatta atatatctcc tgactcagat aaaactgcat ctgttgattc
     1081 aaaaaatatc ttagacgctc tagttaaaca gtttgggcac aactcttgca tatctggcat
     1141 atatgaacct actgcactta ttaaagctcc ttttttcact aagtttccat taagtactgg
     1201 ttgttttgat ggagtagcta aaactatcac atctgcgtta tctatggctt cgtcagatga
     1261 ttcaactgca actattttag tattatattt acttaatttt aagttcattt cttctgcaaa
     1321 tttttctcta ctttccttgt ttctactaaa aactcttacc tcatccaaat ttctagcttc
     1381 tatcatggct tcaagttgtg gctcaccttg tcctcctaga cctatcaaag ctccaatctt
     1441 agaatctttt ttagccaata cgtctatagc tgctccagag gctgctccag tacgaatctg
     1501 agttacataa gtaccatcca atactgcact aacttctcca gtttctccat ctaataatag
     1561 tactgttgct ggaattactg gtttgccttt ttgagcattt ttaggaaata cagatacaat
     1621 ttttattccc ccacagccta attcttctac gtatcctggc ataaataaca tactagcatc
     1681 ttgacttgga acagatatat tggttctcaa aggatttaca ctctttcctt cacaataaat
     1741 tctaaaagct tccttatcag cttcaattgc atctctcatt gtaaatactt tttttatgtc
     1801 gtcttttttt aaaagtagca tttttatacc cccaatttta ataagtctct atgctaaata
     1861 ttatagcata acatttaatt taatcttcta tttcaaatca aataaatcta catactctgg
     1921 ttttagcata gaacttatca acgctttatt tattgaaaat tctggtattc ctgctgcata
     1981 tggagttata tcatacaaat caaaatatac aactagattc tcatcttgca agtaaaagtt
     2041 ttgattctct tttatacctt taaaattata tattccgata ttttcttcat cctttttttc
     2101 aagttcagct atttgtcttt taatttcttc atctataact tctttatatt tagtattatc
     2161 cttaaacaag tccattaatt ctaaaaattt tccagttctc atatccacat tatatgctat
     2221 atcttgataa aatccatgtg ctccaccact ataagtataa tatctcactt ttatactaag
     2281 agcagaatca gtattctttt taagttcaaa gtctacattt gcaacaaact tatttttctc
     2341 gtcaggatta tccttaagat actgctttgc ttctttatat gatttattat aaaattcaaa
     2401 tatgtcattt tttatcttat catttgtaga cctttcaaca attttatttg aatttgttat
     2461 tacaggcatg tttatagtac tttctaaata ctcatcattt ttcactattg ttttacttcc
     2521 tattgtactt actgataaag tttgtttact atttgtatta ccctttggta atgactggtt
     2581 actcataaca gtcactgctt ccttattact atttaaatta attgaagcat ctttccttaa
     2641 attattatat ttatagtcat gtttaattgc caaaacagcc attatagtca atgttaaaac
     2701 aaatacatat cttaaaactt tagcttttgt atcgacttta aaaaatttca tattatcatt
     2761 ttcctcctaa atataaatct ctcttattat atttggagtt tctagggttt tttatccata
     2821 taatttaata aaagattaat ttttatttat aaaaaattaa tctttttgtt ttaaaatatt
     2881 aatatgtctt atcaaacagt ttgaaatttc accaagaggt aattgtaaca taacagaacc
     2941 tctatcaaaa gctaccattg gcattccata tactatacaa gaattttcat cctgtccaat
     3001 tgtaaatgaa ccattttctt tcatttttaa aagtccactt gctccatcat aacccatacc
     3061 tgtaagtatt attcctattg aatttttacc tgctacttct gctactgaat caaacaaaac
     3121 gtctactgat ggacagtgac cacttattct ttctcctttt tcacaagtta cataatatcc
     3181 ttgtttatcc gtacacaatt tcatctggta acccccaggt gcaattaaca catttccttg
     3241 ttctactcta tcattattct tagcttctct tacattcata atacactgct tgtcaagccg
     3301 ttgtgcatac atataagtaa atatagctgg catatgttga actacaacaa tccctggtgt
     3361 tgattttggt aggtctttta taatttcaag tattgcctct gtaccaccta cagatgcgcc
     3421 tatagcaata accatattat taaaacgttc cacattaccg cctccaaaaa atcatatatc
     3481 aaaaatacct ttttatcgtt tatatatagc aggttttaca tatttgtatt tagtactact
     3541 tctgttgatt acttctgcat gtcctacaaa caaaaaacta tcttttttgg tagcattata
     3601 aaatttattt ataagttctt ctcttgtttt taaatcaaaa taaatcataa catttctaca
     3661 aaaaatcaaa tcaaaatgtt gatatgagaa atcattcatt aaattaaacg gcttaaaaat
     3721 tacacttttt ctaatcttat cacaaatttt aaatgtacca tccttgttgt ctataaaata
     3781 cttcttcttc cataactcag gaacattgtt aacatttgat tctatgtata tacctctttt
     3841 agctttttca agtgagttag ttgaaatatc tgtggctatg attttaatgt tccacaactc
     3901 tttattatat ccaaaataat catccaaagt catagctatt gaatacgctt cttctccact
     3961 agaacatcct gcactccata tatttatgtt tcttatttta ttattttctt cccaaaaagg
     4021 aagtatacta ttctgtataa actcaaaatg ttgaggttct ctcataaaaa atgtgtggtt
     4081 agtactcaat ctatttatta ggtttatagc ttcatttcct gtcctatctt taaataatag
     4141 attcatatat tgactaaaag aactaagttt tttctctatc attgtattgt ataagcgacc
     4201 ttcaattaac gctctttttt tacttaaatc aataccatat tcttttttta catggtttac
     4261 aagaactata aattcttcat ctgtgagttt tatcatgcaa aaacttcctc ctgctaattt
     4321 atcagaacta actatatgct attaatcaaa aactttcgaa tatctaaaat taatatagaa
     4381 ttatcttcaa ctttcgcaat ctcttttata tctttattaa tattagtgtt gttagaatta
     4441 gtcgtctcta gtaaatttag attttctata tgaataacat caacaacttt atctacaata
     4501 attccaactt gatactcatc aacctttgta attattatac aagttctctc attataatca
     4561 gctttaggaa gattgtactt tatatgcata ttaataactg gtattattct tcctctcaaa
     4621 ttaataactc cacttatata tgttggaaga catggtacat acgttattga ttgaaatctt
     4681 atggtttcaa tcacattttc taattctatt ccataaataa catcattgac ataaaatgtt
     4741 aatacttgtt taataatttc atctttagcc atactttaaa tcccctaata tatttctata
     4801 atgctatctg catctataat taaacttata cttccatccc caagtattgt acatcccgat
     4861 aaacccttat tttttatatt aaatcggtta aaataaactg gaaatggttt cacaacaact
     4921 tgctgattac ctattatttc atcaacaaaa atgcatactg ctttatgctc attttcaata
     4981 attatcatat taccattcat cagattggtt acttttgttt gaatattata tattttatgt
     5041 aaccttataa tgggaataca tgctccatat attgtaatta actctgtctt atttccttct
     5101 gtaattattt gatttaagtc tgtaagttta aatgttcttc ttatggatga tattggtaaa
     5161 gtaaatagtg aatctccaac tttaaacttc ataccctcta ctatagaaag agttaatggt
     5221 atttttatag taaaggttgt cccctcatcc tgtttacttt ttacttcaat tgaacctcca
     5281 actttttcaa tacttttacg aacaatgtcc atgcctactc ctcttccaga aaattcagtt
     5341 atagattctt ttgtagaaaa gcctggagtc ataatcaaag aattgacctc gtcatcagta
     5401 tactcattac tttgatgttt aagaagacct tgttccttag cttttgccaa aatcttatct
     5461 ctcataatgc ctctaccatc atctgaaata cttatcacag cttctccgcc tagattttca
     5521 gcagataaaa ctatctttcc cacttcttct ttacctttcg ctatacgctc ctcaataggc
     5581 tctattgcat ggtccatagc atttcttata aggtgcataa aaggttccgc taaattatca
     5641 attacactct tatccacctc tgtttctgct cctatagtta ttaactctac atttttatct
     5701 aattttttat tcatatctcg tacaattcta tgcatttttt gaaatacacc agcaatttga
     5761 atcatacgca tagacattac tatatcttgc aattcatctg taagcttgtg taattgtctt
     5821 gttgccttat tgaaattatc tatatcaaca cctgtagaat ttacgctatt tacaaccatt
     5881 gattccataa ttacaatttc tccaactata ttttgaagta agtccaattt ttctaaattt
     5941 acactcataa tactctgctt acttattggt aaatgttcat tttcttcact tagactatct
     6001 ttttccatat cagttttttc atttaaaaca tcttcttgta tctcatcttc tgtatagtta
     6061 ttttgataac ttttacttac tttattatta tcttttaatt tattttctac tgcatcattg
     6121 tttgatgtac ttttcatttc tatttctttt ttactaatat ttatgtattc ttttacatag
     6181 agattatctt ctatagtttt ataaactatt gccttatcct ctttagctac aaattgtata
     6241 taaaacccat aacttttaat atactctgta gactctgcat ttgtttctac atcttttgga
     6301 taaaaatcta taaattcaca gtaatctcta agttcaaata caagcatgaa agctctcaca
     6361 ttttccatca tgcaaccttg ttcaaagatt atttttacta catcagagtc ttctttgtat
     6421 tcaaaatttg aatcgattac ttctttttcg tctttacttt ctaaatttgc attatccttt
     6481 gatttcatag aacttgataa ttccaaagta ctcacatact cttcaattcc ttcaataaaa
     6541 ttagagtaat cagaagatat acaacctctt gattgtaact catctatatc tcttcttata
     6601 aaatctaatg attgaaagac taaatcaaat aataggtcat tgtctaaaac ttctatttta
     6661 ccttcacgta tagcataaaa caagtcttct acactatgtg ctaaagcaga tatattgtct
     6721 aaccccatca tagatgctga accttttatc gtatgcatta ttctaaaagt ttcattaatg
     6781 ttgttatgag taaatacttt ctctttttct atttgaatca taatttcatc taattgttcg
     6841 agtaataaac ttgtctcaaa tataaacata tctaacattt gtctcatact cggttcaata
     6901 taattcacat ttatcaccta cgacctacaa ataattttct attatatatg catctcataa
     6961 tttaaatcct tgatgattct cttatctcac tatatgtacc tcataattta aatacacaat
     7021 tattctctta cttcaatata tatacatctc ataatttaaa tccttgataa ttctcttatt
     7081 tcaatatata tacatctcat aatttaaata catgataatt ctcttacttc aatattcacc
     7141 tcataattta aacccatgat gattctctta cttcactttc ctttagatga aatttttcta
     7201 ctaattcttt taaaatttga gcctgagcag acatctcttc tgaggctgct gcactttcct
     7261 ctgctgttgc tgagttcatt tggactacta tggaaatttg ctctattcca gataaaatct
     7321 gtgtaattgc tacttcttga ctatgtacag ccgaagaaat accattaata taattagtag
     7381 ttttttctac accatttact accaagtcca atgcatttgc agtctcttta gcaattctga
     7441 caccattttc tactgtttta atagcttctt ctatgagaat agctgtattt tgagctgctt
     7501 ttgcactttt accagccaaa gacctaactt catctgctac aactgcaaat cctctaccat
     7561 attgacctgc tcttgctgct tcaacagctg catttaatgc aagaatatta gtttggaatg
     7621 ctatctcatc tattgttttg attatttttg atatttcact cgatttttca cttatttcac
     7681 ccattgatgt catcatatca tccatacatc tacttccaaa accaacttgt gatgcagatt
     7741 ggtcagatac ctcacatgca agactagcac tatctgcaca cttcttaatt ccatctgata
     7801 tctcattaat cgtggaagct aattcttcta ctgaactagc ttgttcagta gcaccctgtg
     7861 aaagagcttg tgcacctgct gcaacttgtt ctgaagcact tgcaacttgc tctgctgata
     7921 aatttatttc agaaaaatca ccattaaaag agtttattat actttctaaa gatattttaa
     7981 ttgatttaaa atcacctata aattcttggt ctatctctac tcttaaatct ccttttgcaa
     8041 tactagttaa tgtactgtct ataaggtcta tgtaatttaa aagcatactt tgcatctttt
     8101 tgacagaact cactaatagc cctatttcag atttactttc ttcaacgtct atacttgttc
     8161 ttaagtcccc agatgcaatt cttgaaaagt gtttttctac tttattaata ggaatcacta
     8221 tttttaattt tattactgta tattctatta ttgtcaatat tattaaaagg gaaagtataa
     8281 atattgttct taatattaga ctttgtaatt ctttttttac ttctacaatt ttggaatttg
     8341 aacgggtaac tatatcctct tgaaattcat ttattaaaga atccattttc tcttgggagt
     8401 ttatatagtc actaccaaaa attatacttt gagctttact cttatcatta ctttcgactg
     8461 cctttattgc actttgttct gttggtacta aagaatctga tatttctttt gcttctaaga
     8521 ttttatttga ctcgctcttt gtaagaccaa ttttttctaa tttgtttaaa gctgattctc
     8581 ttgtttttcc gtataattct ttttcataaa tatctttatt ctttttttct cctgtaaata
     8641 catatcttct taatacatca cttatctctc tagttgtatc ttttatatac tgactttgag
     8701 tcctcaaatt attcatatca ttaatacttt tttctacttt ttcaaatgct ttataagatg
     8761 aaatagaaga aaaaatccct gctagaacag ccaatactat aataatcagc aatacaattg
     8821 ctaatttaga aagctttact tctcttttca tatctgtact ccttcataaa gtaagtttat
     8881 atctttttta atcctttcat tgtactcact acgctacaat cttttcctaa gtttttaccc
     8941 tcatacattg ctttatctgc taaggatatg ttttcttcta atgatatatt tgagtttact
     9001 tctactactc ctaatgtaat agtgcacttt attttatgtt ctttatagtt gaaatcaaac
     9061 tcctttatct ctttacggat tctttctgaa agtatcttag caccttctat tggagtattt
     9121 gtgagcatta tcaaaaactc ttctccaccc catcttgata cagtatcaat ttgtctacaa
     9181 ttctttttta ttatacttga tattactgtt aacacgaaat cccctgcttc atgcccataa
     9241 gtatcattga taaccttaaa gtcatcaata tcaccaagga taagggatat tgatgtttca
     9301 ctatatttat taattcttct ttgctccata agctgattaa ttatatgtcg cctattgtaa
     9361 agacctgtaa gataatctct tacaacgagt ctattcaatt tttcaagaga agattccagt
     9421 tcattattta tcttttttaa tttatcttga gatttcttta cttcaagatg agctataaca
     9481 cgagctttta attctgtcat actaaaaggt ttcaccatat agtcaattgc tcctacacca
     9541 aatcctttta ctatgtctgt atctgtattt tttgaagtta taaaaattat aggtatatct
     9601 gctgtacgag cattagattt tacttcctta caaaactcaa aaccagagtt atctggtaaa
     9661 attatatcaa gcaaaataat gtctggtata aattcttcaa taaattcttt tgcctctatt
     9721 gcattaaatg cttttttaac cttaaaatta tcttttgtaa gtgttttatc tattaagtca
     9781 cacatcagaa cactatcatc aacgactaaa attgttccct gttgcttatt tttcatatac
     9841 aaacctctct taaacataat atattcaaat tttaatgatt taaaattttt atacttaata
     9901 attataccac tatattctta aatgttctca tcacaatctt tttataataa cactccaact
     9961 acatccctat gttacatgat agtgcaatca aacccattga ttaattcatc tattaaaact
    10021 tcatctttat ctgtcaaaag tttctccaaa tctagtaaag taattatttt accttctaat
    10081 tctccaactc cacttacaaa ataatccgaa tattctatag taactcttgg tggaggtgat
    10141 attttacttt tttctaagct tactatatca tcaactctat caaccacaaa tccaactacc
    10201 aagtccttta tttcagttac tactatatac atgcaatttg tagtcattaa ttcatctttt
    10261 ttaagtctca aacgcatatc tattatcgga atgatttttc ctcttagatt tattatgcct
    10321 ttagaatatg taggtagttc tggaataaat ataatttctt gatttccagt aatttctatt
    10381 accttttcaa gttcaacccc aaaatcttgc tcatctactt taaactttag atacttaatt
    10441 ccttcatcaa ttagtccata atctaaatat gggtcatctg gaaatctcat ttaatacctc
    10501 cctcctaaaa tacactttct atgaaatata tattataatt tcttcttacc tttatttatt
    10561 gaatctacaa gtaattcacc cgtctcagtg taaaaacgta ttgttctacc ataattcata
    10621 cctgtgtcct cagctaatat tggaatattt aatcctaaaa gagttttttt tactgcctca
    10681 acattcctat gtcctatact tgcaattact gaattgctac ttcctaaaaa catctgagca
    10741 cctccagcaa tttttgcttt tatatatatt ctatttgcac ctatattctc catagattta
    10801 atgagctcat ttattcctgt gtcagcaaat ttacacttat tttcaatgtt aatagcatct
    10861 ttactatatg gcaacataac gtgtaacatt ccaccaattc cagctacttt atctatcaaa
    10921 catactccta cacaagaacc aagtgcataa gtaactaaaa catttggtct ataggctatc
    10981 ttcatatctg caatgttcac tactatctct ctattcatac ttctaatccc aacctcacga
    11041 gtatttctct aagtgagctc atttctggaa tcatcaaaat gtgactagta aaataattat
    11101 cactcatttt aaatttattt tctataaata agactttgtc accaacatct gaaaatctta
    11161 tcataggtac atttagaaca gctccaacca tatcaataca tatatctgga attgaaacac
    11221 ttatagtcat gtttaacata gatgcaatag catttacata tgaacttgcc ataatatttc
    11281 ctatttcctt aattgctgaa atttcaattg cctcaatctc atctaaaaaa gcttcttctt
    11341 tattaaaaag agaacttagc ataagttgag ttattgattc atccaacaaa aacataaaca
    11401 ttccattgat atcacctttc atatcgagta aaatacatac tactttgttt tctggaccac
    11461 caagcaaatt tgtcgcttca ttatattcaa gtatcttgac cataggtatt aatacttcta
    11521 cattgctatt tatcatggat gcaagtgcag taattgcatt cccagagcct atattaccaa
    11581 tttctctaag agcatctata tgaacatcat caagttctaa ataatttata atataaaccc
    11641 ctccctttat tattgcattt atttgctttt cattgtatta gtgtatattt acacttttat
    11701 tttaaagcat tatctacaac tttaactaat gtttctgttt tgaagggctt cactataaaa
    11761 tctaacgctc caagttttat ggcttctaca atcatattct cttgtcctat tgcagagcac
    11821 attacaacct tagcacttga atccaacttt tttatttctc ttagcacctc taaaccatct
    11881 ttttttggca ttgtaatatc aagcaacatc aaatcaggct tttcatattt aaatatatta
    11941 cacgcttctt ctccatcatt tgcttctatt aaattattat agccactttt actcagagct
    12001 tctttaatta tcattctcat aaaaatagca tcatctacta tcaaaatttt attttccata
    12061 aaactaactc ctccatatgt acaacaataa acgcttttat cttcagttat tgtctatact
    12121 atctgactat ttttcgctac acaataaata catttcattg ataaataaaa gtaattattt
    12181 atgccatatt atacttaatt ctcttaacat aatttgtcaa caaaaaaact tatatatcta
    12241 ttgtaatata tgtttggcgt tttgacgagt tattaaaaat ataattgtat aaaacataaa
    12301 aagttatcaa aagtaattaa attataataa aacaacttta tacctttttt atgtttgtat
    12361 aaaaaaaatt ttcagattca ttaaaatcat ttctgtagat tcatatagga tttgactttc
    12421 tcaatatcta atagatagtt gtttatttac ttaattatat ttctctatat gtattatcga
    12481 ttaaattaga tttagcttta tacattattt tttatatttt tcaaattgta tactcataaa
    12541 tccagaagta ttctaatgtg tttataatac tttttttcat attttaaatt aaataacaaa
    12601 tcattatatt tacaagtatc atttatcaat aaacaatatt aaatgaagaa tatgtctgaa
    12661 gattcaaagt gatactgata ctattaatta ctaaaaaagc agtaaatctt ttacagattt
    12721 actgcttata gttataaata ataaaactat ctataataaa tgtactatac tcaatatttc
    12781 attcaatata gtaataacaa atctacttta ttcctatgta aatatgaatt tcttgtttct
    12841 ttgtatcaaa agtattacat tgatactctt caaaatcact tatataagtc ctatcaaaat
    12901 ccatttgcca aaactcaaac caaaaatctc ctacttcttt ttgacctcct actataacaa
    12961 actttgcata cttacctgct ggtataactt tactaataat actttctcca acagtattat
    13021 tagtgtttaa ttcttctaaa ttcttctctt tatcagaatt actatttact tcacaacatg
    13081 caacaaagct atacggactt gtaaaatcac cctggtaatc tgtatataga cctattgtct
    13141 tgtcattctt tttacccttt atagcattat atatcccttt gcccataaat tttttccaca
    13201 attcacctat atcatttacc gcttgtccat ctttatttgt agtctccttc gatattccta
    13261 taactatttt ctcatttatc tctactattt cataattcat actttatacc tcactttgtt
    13321 tttattaatc tattttattt tgaactaatt caattataat ttataatata cgacaccttt
    13381 atgtcatatt tttaatataa ttaaactcag tgagatatta tatactaaat gcaagatatt
    13441 atatatttaa taaaatcttt aatctagcat tatattataa tgaataaatt ttagacaact
    13501 cccttagtct agttattaca ttatccctaa catctttagg ttcaagtact tcaacattgt
    13561 caccaaatga taaaatatat ccataaatcc attcaccaat aggaaattct gtaattacat
    13621 catatgtatc atcttcattt ttagttatta aatccttatt aaaatcatca aatactctaa
    13681 aaagcatctt ttctttaaac ctcaatttca acgttatagt attttcctta attactttag
    13741 aatcattcaa acatacttct tctattatct ttcttgaaaa tacttcatcc tttatagata
    13801 aattccttat cctactaatt ctaaatatcc taaaatcatc ttttagttta caaaatccat
    13861 acaagtacca agtcttactc ttatacataa gcttcagtgg ttcgacagtt ctgtttgtct
    13921 ggcttgacaa actatttaca taattaaaat ttatagtatt acgccttaaa atagcttctt
    13981 ttatttttgt aaatttatca tcttcattaa aattacttcc ccattcagta aagtctattt
    14041 caatccagtt tgaaaaattc tgctctccaa atattgagcc aattttattt actactgaat
    14101 ttatttctgg atacttagtc gcctgtaatg ttttcagtgc aactattaaa ctctctttat
    14161 ctttttttga caatatagcc ttgtctatag aatattcttc tattaaagat atccctcctc
    14221 ctttgccttt cgtcatatat actggtactc ccgacataga cagagtttct atatctctat
    14281 atatggttct tgtagaaact tcaaatctat ctgccaactc tttagctgtt actaattttt
    14341 tatttaatag aattactatt atttctgtta atctatttat tttcattcat taccacctac
    14401 taaaattatt aaatttattt aatctaaatt aatcatacta atttttaaat aaataaaatc
    14461 ttagaatctt atctaaatta tttttacatg attttattta ctttctatta tctttctcac
    14521 tttggatatt atcatcttaa tttatttatt actatatcaa tttacttatt atcatctcat
    14581 ttgttatcgt cttacttaat ttacttattt ctatatcaat tcacttatta ttacctcact
    14641 tgttatcatc ttacttaatt tacttatttc tatatcaatt tacttattat catctcattt
    14701 gttatcgtct tacttaattt acttattgct atgtcaattc atttattatt atctcacttg
    14761 ttatcgtctt acttaattta cttatttcta tatcaattca cttattatca tcttaattca
    14821 tttgcttatt atcatttact ttattcaatt tctatatcaa aattagtatt tgtacttaat
    14881 acttaaaatt aatttaaagt ctttacatat tatttatttt ctattgtaat attcatttcc
    14941 atactttact aagctacttc cactcattta ttttaaaatt tcaatttact atttctcaac
    15001 tctatattat tatttttcaa ttttatatta ctaattttaa agctttttag ctattattcc
    15061 tacaatattt aaacaatttt ttcataataa agctatatta caatatattc aaaatatgta
    15121 atattttaga tatttttcgt tgacaatgtt aaatttttgt tttatcctta attaaggaca
    15181 tgttattgac atttctgaaa cttatttgaa atagtttttt cattttattt aggaaaacgt
    15241 attatactta agaaaacgta ttttctcatt tcagataagt aaaatattta ttcttttggg
    15301 gaggaaatca tggaaattaa taaaaaacat tttattcaag tatttttaac ttgcttaatc
    15361 ttggtagtaa tatgtgaatt tatagggcaa agaactatag ctattggaaa agcctctata
    15421 gtactgttcc ctatgcttta tgcagttata attggactta taataacacc agatttatta
    15481 ggtaaaaaaa ttaaagcact taaaaaagtg gttggagaaa aagaaataaa tattgctggt
    15541 gaagttgttg gaattgcact agtaatgctt ggtataaaat atggtactac agttggacca
    15601 aacattgaca aaataattca agctggacca gcgtttatcg ctcaagaatt tggtcatata
    15661 cttgcaccaa tcgttgcatt acctcttgca ttaatgtttg gaatgaaaag agaagctgtt
    15721 ggagctactg caagtataag tcgtgaacct tctttaggag ttatatcaga aaaatatggg
    15781 ataaactcac cagaaggtag tggtgtactt ggtacatatt taatgggaac agttcttggt
    15841 actatatact ttagtgtact aggttcaata tctatttata gtggtcttca cccatatgct
    15901 ttgggaatgg cctgtggtgt tggtagtgga agtatgatga cagcagctgc tggttcatta
    15961 tctaccatgg taccacctga aatggcagat acaatacttg cctatgctgc aacaagcaat
    16021 atgatgtcta gtataacagg aattatattc ttagtttttg tatccttacc atttactaat
    16081 tttatgtata agattttaga acctaaattt tcgagaaata aaaaaactaa agaaattaaa
    16141 tctacagaag gagagtgcta ataaatgttt gctaatttaa atttaaagaa aagttcatat
    16201 caattattgg ttatgtctgt tattggagtt ataattctta taggacaaag aattagcgtt
    16261 ggtacatcta tagttacagc tcttcctggt atggtgatgc taatattagc tgctatggca
    16321 gctatgatta taaaagattt atttcctaaa tcaatctttc cagcttttgg atttgcaact
    16381 ataatcggcc ttttacttag tatgccatat agtccaacat ctgaagtatt cttaactaac
    16441 actaataata ttaactttat ggctataact actccactac tagcttttgc aggaatttct
    16501 gttggaaaca aaatagaagc tttaaaagaa atgtcatgga aaatagttat aatttcactt
    16561 attgtattta caactatatt ctttgcatgt gcgagtatag ctcatatagt tttaagtatt
    16621 caaggtaaaa tataggagga atttattatg aataaagaac aattaaaatc tctagtaata
    16681 aaaactatag atgaaaatag agaaaaaata ttaaaaatag gtcaaggaat atacaaaaat
    16741 ccagaatatg gatataaaga atttaaaact acagaagctg tttcaaactt ttttgagcaa
    16801 gaattaaatt tatctgtaga aaaaaatata gcagttacag gatgcaaagc agatgcaaat
    16861 tctagcaaga aaggtcctca tatatctata cttggagaat tggatggtat atcatgtaaa
    16921 gaacataaag atgctaatga aataggtgct tctcatactt gtggacataa tattcaaata
    16981 gctggaatgt taggtgctgc tgttggttta gtaaaaagtg gcgttttaga acatttagat
    17041 ggtaaagtat cttttatggc tactcctgct gaagagttta ttgagttgga atacagagag
    17101 caattaaaaa aagaaggaaa aataacttat tttggtggaa aacaagaatt aataaaaaga
    17161 ggttattttg atgatataga catatctatg atgtttcatg cttctgattt aggagaagat
    17221 aaggctctag ttggtcctga gagtaatgga tttgttggaa aaaaggttaa atttataggt
    17281 aaagaatctc atgctggttc tgctccacat gatggaataa atgctttaaa tgcagcaatg
    17341 cttgctataa acaacgtgaa tgcacttaga gaaactttta aagagtctga aagagttaga
    17401 ttccacccta tcatcacaaa aggtggagat atagtaaatg ttgttcctgc tgatgttcat
    17461 atggaatcat atgttagagc tagaactata aatggtatga ttgatgctaa tgaaagaata
    17521 aataaggctt tgatggctgg tggaatggca gttggagctg atgttgagat aactgaaatt
    17581 cctggatatc ttccaatatt acgatacaaa agtcttgata atttatttaa aaacaatctt
    17641 gaagatttag gtctaaaagg aaaagttatt gatggtggag attttacagg ctcttttgat
    17701 tttggagatg tgtctcatat aatgcctact cttcacccta tgattggtgg tgtaaaagga
    17761 gctcttcata caagagattt tgaaatagtt gatgaagatt tagcttacat aattcctgct
    17821 aaagcaatgg cacttacagt tgtagacctt ctttttgata atgctaagga tgctaaagat
    17881 atattagata cctttactcc agttatgact aaagaagaat atctaacatt cttagaaaaa
    17941 cacgataaaa ctttataagt ctatttttat aatagggtgg tatctactgt aaaagttata
    18001 ccactctttg tttttgtaac agtatacttc ttttctttta gtttttagat taaactaaaa
    18061 tatattatcc tccttaaaac ttttagagct acgttgaaat atcagtagaa ctatgctata
    18121 ttctttctaa ttaatataaa tttctattct aattcaaggt ggtgaaaaaa tgtttaatgc
    18181 aggaaatcga attataaata catggttgta ccctattcaa gatggctttg tcttgattga
    18241 tactggatat gaaaatggtt ttaaacattt caaaaaacga atttctaaat tcaacataaa
    18301 aatcaaagat attcgataca tatttctaac tcatgctcat gatgaccatg ttggttttct
    18361 aaatcagatt ctagacgaat ctcctaatac aaagattgtt atgcatgata aagctttaga
    18421 aattctatat aaaggtcaaa actcttttat tggtggttgt accagccgta ctgcctttct
    18481 cttttgccaa attatgaaac tatttggaaa aggtgagcat agtttttctc cacttaaaca
    18541 agaatttgaa aaaaggtgta ttcttgtgtc tgacaagaat cgtaaagaaa ttgaaaaaga
    18601 actaaatgga aaaattatag atacaccagg acatactgat gattcaattt cactactaat
    18661 tgatgaaggt gttttatttt gtggagattc tgcaatgaat ggatttccaa gtactcacaa
    18721 aattaccata tttgcagaaa gcaaactaga atttattcaa tcttggaaaa caatcatcaa
    18781 tacaaaacct aaaatgattt atcctggaca tggaaaacca tttgaataca gtaaattaga
    18841 acaaaatcta atctatgtaa ataaaataaa tttatatcct ctacataatt caaaagatat
    18901 tcacagattt ttgtagaaaa tacaaagtaa atttatttga ttaattaaaa aatctaacac
    18961 tttactacgc tacttatttt aataacttaa tcttccacta gcttttcata aaattttgtt
    19021 ttaaaattaa ttttaaagtg catatgttat ttaaatacat tagataaaat tcgtcattaa
    19081 tctacttaaa gcatatttaa ctaacaccac tcaaccagaa aattcagaaa actgcattga
    19141 cacaggaaaa agtttatttt atactttttt taggacatat tgtggacacg tcttaaatcg
    19201 acaaacagaa tttaaattgt aagattaacc acaatactta ttttttaatt atatttttaa
    19261 acattaggga ggatattatg aatgataacg tagttaagaa gaaaaacttt tttgacagga
    19321 cattaaacag aatagaaact gttggtaata aactaccaga cccagttaca atatttttag
    19381 ggttatgtgt acttttactt atactatcta gtctagttgg ttctatgggt atatcagtag
    19441 ttcatcctgg tactggagaa actataaccg ctgtaaattt attgactgta gaacagcttc
    19501 aaattctttt aggaaacata gtcagcaatt tccaagggtt tgctcctttg ggtctagttc
    19561 tagtaactat gataggtgct ggtgtatgtg acaaaacagg acttatgaca gcaacaatca
    19621 aagcatcagt aagcaagatt cctgaaacaa gagtaactct tgttgtaatg actataggta
    19681 tgcttgccaa tatagcttca gatgcaggta caatattatt tccaccatta gctgcacttg
    19741 tatatcttgg tgttggtaga catccactta taggtttatt ttctggatat gcagcagtct
    19801 gtctaggatt tgccgcaaac attatgataa gtgtcaatga tatacttgct gcaagtttta
    19861 cagttccagc agctcaaatg attgattctg gatttcaagc caatgcaaca atgaacttat
    19921 tttttatgat agcatcaact tttgttctaa tacttttggc aacatgggta acagaaaaaa
    19981 ttgtagctcc tagatttggt aaatatgaag gaaatgcaga actagatgtt gatggaagtc
    20041 ttagtgatgt agaaaagaaa gggcttaaaa aagctagtat aagtatatta atatatgtgg
    20101 ctattatagt agctcttagt gtaatcggta aaaaaccatt cttagctgac ccagaaacag
    20161 gagatttact atcaaacaat gctcctctta tgaaaggtat ggtacctata atagcactag
    20221 catttttcat acctggtgtt gtatacggaa aaactatagg taaaataaag aaggataagg
    20281 atgtagtctc tataatggct agtgcaatga gtgatatggg tggatatata atactagcat
    20341 ttgctgcttc acaatttttg caattattca caaatagtaa tttaggtctg atactagctg
    20401 taaagggcgg agaattttta aaatcagcag gaataaatgg acctttattg ttgataggat
    20461 ttattatatt atcatgtttt ataaatttat ttataggtag tgcatctgca aagtgggcta
    20521 ttcttgcacc tatatttgta ccaatgttta tgatggttgg atacaatcca gcacttactc
    20581 agatggctta tcgtataggt gattgtataa caaatccact tagcccatta tttccgtact
    20641 tccctattat actagcattc acaagaaaat acgataaaga tgctggtatg ggtactgtaa
    20701 ttgctaatat gataccatac tctatatcat tcttaatagt gtggactata ctattaatat
    20761 tgtttatggt atttaatatt ccactaggac ctggaatact tccttcatat agcatgtaat
    20821 ttatttaaat ctttctaaaa ggagaaataa tttatgttag ataaaaatag acttataaat
    20881 aattttatgg atatggttag aattgatagc ccatctaatc aagaattaga aatgtctaag
    20941 tggttggtaa actacttaaa agaaagaaat atagatgcca ttatagatga tgcaggtgaa
    21001 aaatatggtg gtaatacagg taatgtcatt gcctatataa aaggtgaaga aggaagtaga
    21061 ccactttgtt tatgtgcaca catggaccaa gttcaacctt gtttaggtgt aaaaccaata
    21121 ctagatggta atgtagttag aagtgatgga actactacac ttggtgcaga tgataaagct
    21181 ggaatagctg ctatacttga agctttagaa catgttatta cagaaaaaat accacataga
    21241 gatatttatc tttgttttac aatctgtgag gaagctggta tgcatggtgt caaaaacttt
    21301 aatcctgaca acttgccttg taaagatatg gtgattttag attctggtgg agctattggt
    21361 tcgatagcat acaaagctcc tgctcaacaa tctataaaaa tctcttttca aggaaagaaa
    21421 gcacatgctg gtatagaacc tgaaaaaggg ttaaatgcta tattagtagc ctctcatgca
    21481 ataagcaaca tgcacatagg cagaatagat tcattgacta cttcaaatat aggtgaaata
    21541 gaaggtggtg gagctacaaa catagtaact gataaggtta cattgactgc tgaaattagg
    21601 tctcatatac ctgaaacttt agagtatgag cttaatcata tggaaaaatg ttgtaaggac
    21661 gctgcatcta aatttaatac tacttatact tttgaacata atatgtctta ccctagtttt
    21721 gaacttagta gagatagtca tgttttcaag ttaagtgaag aagcaataag acaagttggt
    21781 gttgttccaa atccaatggt aattggtggt ggaagtgacg caaatatatt agctaatctt
    21841 ggatataatt gtgctatatt aagtctaggt atgtatgatg tacacacagt taatgaatat
    21901 gtaaatatag acgaattata tgatactgcc aaaatagttt atcatatgat taaattataa
    21961 atatcataat agaactcttt aaattataaa aataaaaacc tatgtatcct caactttata
    22021 agttatatat tagagttgtt ttacataggt tttagtattt ttatataata atttgtttta
    22081 acatttttca taataagctt tgatatttta tatagtaatt tgttctaaca tttttcataa
    22141 taagcttcaa tattttgcat aataatttat tctagcattt ttaataatag gctctagtat
    22201 tttatattaa taatttattc tagtatttta cataattatt tgttctaatt tttttcataa
    22261 taagctttaa tactttatat agtaatttgt tgtagaattt tatacaatat aatgatttat
    22321 acagttttat aaaatatctt aaaacagtat ttcagtaata ttttttggtc ttcctccacc
    22381 aatactagtc tcttttgcac atattcgacc taaacctgca tttactattt tatttaatat
    22441 acgtcttgca cttctttcac ttacatttag atactctgct aactcttttg aatcataaat
    22501 cttacttttt ctattctcat ttatagcaat aatttttgca actgactcac aactcattcc
    22561 agtcttttta gatatttcga ttaccttttc atcagatagc atcaaagaat aatttaattc
    22621 attttcggaa gctaaaggtc ctcttatgtt ttcatcttca tctaccaaat atataccaat
    22681 ttcttttgaa tctatggagt gtcttaatgc tttatgtgca ttattttcag cctgatacgc
    22741 agttactcca gtaccaattc ctatactaag agaaaagccc atgtctttta tctctctctt
    22801 tagattgaat agcttatcat aattatactc attatcagct acccctttat gaacaaatac
    22861 aacataatca tttcttccaa gtaaaaataa ggaaccttga atgcttctta catagtttac
    22921 tacaagctta tccatatctg atttttttat catgtcagaa taatagttat ctatcttctc
    22981 tttataatct attaaactca atatttcaac agcaatttgg gaaaatcttg ccttacttag
    23041 agcatattca ctctttacct tgtcataact ttctttgatt aattgtatag tagcttgtaa
    23101 acgaaataca ggatagcctc tttcttttaa ttcattatat actgcaccaa aaccagtcaa
    23161 cattatatcc gtcttatttt cttcaaataa ttttatatgc cattctacaa gttcagactc
    23221 tcctacttcc aaagaaaatg gattacaaaa tacactcgtt gctttaatat caaattcttt
    23281 aagtgcatct tccacaacat atctatcaac tacatctata ctgaatttat ctaattttat
    23341 atttgcactt tttattgccc aaaatgcctt cattatactc gtcccacttc tcggtacaaa
    23401 tgaatgtggc ttacttatct catacttaga ttttataaat tcataaactg cacatcctgt
    23461 aaatataata gcatcacatt cgtcttcaca tttagaaata acttctattg tatctactac
    23521 tttttctctt acatatattt tagtctttaa atcactgtct atctgtttta aatcatcctt
    23581 tatcttaaac ccagagtctg aaggacctat aatacccact atcataaact tcgctcctaa
    23641 tccataaata ttatactttt taaaaattat atcctcacta ttttctactt ctatttaatt
    23701 attttgaact actccatcct acctacattt agaatggaat aattagctta tttttgataa
    23761 agtaacttct caaaatcagc acttggaata ggcttacaat aataataacc ttgaattacc
    23821 acacaatcta aagtcactaa aaattcagct tgttcttttg tctctacacc ttctgccact
    23881 acatccatat ctaaatcttt tgccatggct atagtgtgct ttaaaactat tttttctctg
    23941 tctgtgattc cttcctcatt aaagaaacca caatctatct ttaatgtatc aatattaata
    24001 ttttttaaca tatttaatga agaatatgct gaaccaaagt catccatatt taaaacaata
    24061 ccatccattc taaggtcggc tattatctta gtaaataatt ttatattttt aataaataaa
    24121 ctttctgtaa gctctaattc taaaaaagat tttggtatac tatatttatt tattaaactt
    24181 aaaacaattt ctttaaaatg tggattatgc aaatgtaatc ttgatacatt tacagagata
    24241 ggaactggct cttcacctaa atctatccat tttctaatca aagaacatac ttgttcccat
    24301 acatacatat ctaatctgat aataaaccca ttcttctcaa atagtgaaat aaatttaatt
    24361 ggaggtatta tacctttttc tggatgaacc catctaacca atgcttctgc accaacaatt
    24421 ttatttgcat taagattata cttaggttgt aaatatacat ggaattgccc attttcaagt
    24481 gcgtattcca tttccctttc catctgtttt tcttcaagtg catcatttct tatagtatca
    24541 tcataaaata tatagttatt gatactttgt ttctttactt ttttgtgagc atatcctgcc
    24601 atttcacacg catttgtaat tggaatatga ttatccaaaa ttctataaac cccaaaacat
    24661 ggtactaaca tatattcaaa tttttttcta tttaagctat ttttaatctt ataaattacc
    24721 ttatgaatat ctctatcaga gtaactctca taaaaaatgc aaaatacatc tgcatacata
    24781 cgacaacata taccattaga accaatgttt ttttgaatca actctgcaac atatattaaa
    24841 gctttatctc ctcctctaac tccataaatg tcattaatta ccttgaactt atctatatcc
    24901 atcattataa ttgcataacg cttgtcagga tatcttttaa gcattaaact tatttgttca
    24961 caaaaacttt cataattgta tagtcctgtt aatgtatctt tttggttttt atgtagttgc
    25021 ataagataat ctatattttt tatagcaact aaaatatgtg tttgtttctc acctaactta
    25081 tttttactac taatctttaa catataaatt aatgcccaat agtacttttt atctattcct
    25141 aaacgtctat actcaaaatt tagttctaaa tcgtcttgct tgctattatt aagactatca
    25201 agagatttta gaaggtggtt atcattaaat aatattatat catcaggatg aattaaatgt
    25261 ttttttatgt atgaaaaagt tttttcaaga ttttccttta taggaaaact aaaaatattg
    25321 ctctctgatt gataaattgg agtaattaaa ttcgtatcaa tgcaaataga taaaattata
    25381 tcatatgtat tataagctaa tttttcataa gccttagaat acccttttat cattaaatca
    25441 tcaaaataaa ccttatcaac taactcttta tgtttaaata aaatattatt cgtcgaatca
    25501 gctaagtcac taattacttt catttcatta tttctaagtt tgttcttatt ataatacctc
    25561 ttcttatctt ggtacattct ctcatcagca actttaatta gcttatgtat atcaatatta
    25621 tcgtcactcc aaatactgcc cactgctaca ctatatatca tctcatcctt aaattcttca
    25681 cttaaccaac tcactaattc ttcaaatagt tgttttgata tatcttcaca taatacaaca
    25741 aactcatctc ctccaatacg gtaaacatta taagaatgaa agtatttttt tattattaca
    25801 catgctgaca caatagcaga atcgccatta gcatgtccaa agttatcatt aatatctttt
    25861 aacccattta tatctacaaa tacaactcct atggatttaa cttttccttt ttgaaaatta
    25921 tctatatact taatatattt atttctatta tatgcaccag tcaagaagtc atagtagctc
    25981 atataattta atttattttc tacttttctt tttttcatct cagttaataa aaaataagat
    26041 agggatgtca aaagagaggt atctccaaca gctttatgtg gattatcaac tccaataaac
    26101 cctactactt tatcatcttg ttttagtgaa gatgtcatta aactttcaat tttttgaggt
    26161 tttaaaattt catattctat tggctgttct tcttttatat tttctatatc atcaattatt
    26221 acaaaacctt tttgttcgaa taataaaaac caattcttta attcattaat atcaagattt
    26281 gttagtgcct gtttttgttc atcaacacct tcattgcacc attcatatgt attagttact
    26341 ttttttctat cttctgatac ttcaaaaaca tatgctctat cagctttatg aaatttacca
    26401 atattggtta atacaagatt tacagcatca gaaaaattag attctgttat aagatgttta
    26461 atacatccaa ctaataactc ctttatctct aatttttctg ctattgactt acttatatct
    26521 tccttttctg taatatcaag agctatttct aatcgtgcat gtttgccctc ccatttaatt
    26581 aacttgtcct ttaatataaa atgtctattt gttcgagtat tcgtattttc ccatatgtaa
    26641 tattcatctt cttttaaaat agagtttgta caaaattcgc agggagaatc tttcccctgt
    26701 aatgctttat aacattttaa atgggatata tcattaagtc ccattgcctt tttcccaatt
    26761 tcattaatat ataaaagttc atatgtatct aaagaagaaa catatacaat ttcatccaac
    26821 tcatctatta aatttattac atccatttat atatatctcc ttttattcat tttccagatt
    26881 gaatttttaa agcttttaaa attttgctat atatttggca atgatattat atttctttat
    26941 gttttaaaat agtaccttaa tgaggttcta ttttttagta aatagaatta ttattgtgtc
    27001 aatcgtacaa tagagttttg taatacctaa tttaatatat ttataattaa ttatctcatt
    27061 atgtgtttat aattaattct catataaatg acaaatctcc acctcaatta agtattccaa
    27121 tcatatatga agataatact tcattcattt aaaaatataa aactattata tattaaaatt
    27181 tcttcaataa taaattatct agattgttac tttgatatat tatataatat cacaaaggct
    27241 gatataaaaa gacaaaaagg gcaatttttt tatatcaaaa aaaaatgtta aattgatatt
    27301 atccatatat aaattgatat tatccatata gatgctatat ttaacaattc tacttacttc
    27361 ccttacactt attagcatat agttattaag agtttgttgc aaaacaacac ttagcacact
    27421 ttaaaaagtg tggtctaata agtaatcaac gaagaagaca taataaagca taaaatatga
    27481 tatacttttc cacgccatca aaactgagga ttttattatt aatatatgct aaaatatgct
    27541 taataaatta aattttaatg ggagaatagt tatgaaaata tttagtttct tgttgtttgt
    27601 gataggaata tgtttatgta ttgctggatt tataggacat tacccagtat ttgttggtac
    27661 aacattgagt tttcttgcaa ttgcaatgat agctgtaaga caagtcaaaa ctaagaaaaa
    27721 aatgaaatag gcaaatccta actttacaag ttaatattac acaagtaatt agtctaaaat
    27781 tggatacttt ttctattaca gaaatacatc atccactttg tattttctta aaaaaataaa
    27841 atagctatgt aaattcaaga ttagatagat taactctcta tccatttcat tgtaaaatat
    27901 acatagctat ttgtattcga tttaaaatac ttagattttc ttacataaca aataatttct
    27961 atctgattat tactcatatt catttagtaa ccactcagca actaatcatt tagtatctat
    28021 tcatccgcca tacggtaacc taccccaacc tcagtcaaaa tatattctgg ctgagcagga
    28081 ttcttttcaa ttttccttct tatacttgcc ataaaaactc taagcgactg attttcactt
    28141 tcatagtaat ttccccaaac tttatctatt ataaacttat gggttaagac tcttcctgaa
    28201 tacttagaca tcaactcaat aatcttatat tcgattggag ttaaatgtat ttcttcacca
    28261 ttaattgaca caatatgatt ttcataatct atctttaggt ttttaacttc aaaagacttt
    28321 ggagcatcat tatttatatt atcctgttga gctttatttc taagagccac acgtactcta
    28381 gccaaaagct ctgttacact aaaaggttta gttaaataat cgtctgctcc tccatctaaa
    28441 gcttccacct tatccctctc atgctctctc gctgaaacaa caattatttt attagtcttt
    28501 gcacatgccc taactcgtcc tattacctca atcccatcaa tatctggtag tcctaaatcc
    28561 aaaattatca aatctgggtc aagagaatgt ataagtgata tagctgttcc tccattatct
    28621 gtctctacac acctataatt ttgagtttca agagatactt ttataaattt acaaattggc
    28681 ttatcatctt ctacaattag aactaatggc tttatttcca cttgtctttc ccctcctcat
    28741 catacatagg tatgctaaat ctaaatgtag ctcctccaga aggattatta aaggcgacaa
    28801 tttctccacc atgagcttct actatagatt tacatatctc caatccaaga ccaatacctc
    28861 ttctttcaag atttctagac ttattcttag tataaaacct attaaaaata ttcccgatat
    28921 cttcatttgg tattcctttt ccattatctg caacttcaaa tagtacttga tttgactctt
    28981 tttttacagt tagttctatc ttagaatttt taggtgtatg ccttatagca ttatcaatta
    29041 gatttactaa cacttgttct attaataata catccacatg aacgattatt atctcatctg
    29101 gaatatttgt ttttatgtct ctactattgg caaacttttt gactcttaat atagattcag
    29161 ctattatttc atcaacaact tctggtcgtt tttcaatatc caattttcct tcatctattc
    29221 tggtcatact aagtatattc tcaacagaat gagttagcca actcgtatct tcatatatat
    29281 ttttcaataa ttctactcta gtttctttat ctatcacatc atcattttca agtattgttg
    29341 aagatgaacc taatatactt gtaagtggag ttcttaaatc atgagaaatt gacctaagca
    29401 agtttcctct taatctctct ctctctgcct caagatttgc ttttttattt ttctcaaata
    29461 aattttctct atcaattgcc aacgcaacct gtgttgaaac tgcttctaat agtatctttt
    29521 cattttctgt aataatatct atcttaaaac acgcaacacc tataacacca agaacatttg
    29581 attcttgacc ttttataggg aaataatatg cactgctgtt tttacaatat tttgtcccaa
    29641 ttccaactgg gttacctgtc ctaaaagctt cttttatagc ttctttttct aatactgaat
    29701 ggaatatatt ctcacttcca tcattgttac aaatataaat acttggctta cctagattat
    29761 tattctcatc tgcaatagtc actattacag ttctatttaa tatatttact aaattagacc
    29821 cacaaaattc aataatttga tttttatttt ttgctttaag caacgttttg ttattctcat
    29881 agagcaatct tatcattttt tctctcttat gagaaagtct cacttctctt tttatcctag
    29941 aagttaaagt acttgttata attgctgcca ttagcataat acaaaaggtc ataggataat
    30001 cttttctata agctaaaaaa gtatataatg gatgcgtaaa gaaaaaatta aatgatagca
    30061 ctcctattac tgaagaaagt attccaaaaa aatatccata ggttatactt gtagcaaata
    30121 gtacacctaa tatgtatact agtataatat tagattcatt aaaacctacc ttttcaaaaa
    30181 ctactgatat tccagtagca attgtcataa ccaatatagt ttttatgaag tccttaataa
    30241 ttatcttttt actgagatag ccatcttcat cataatcata ctcttttaag tcttcatgtt
    30301 gtagtcgttc ctttttcatt tactacaatt cctccttatt gttactgttt aaattggctc
    30361 tattttatat aatacaattt tatcataata aattcaatca atacatttaa ttaatgtact
    30421 taaattacta aaaggtgctg tcttaaaatg aaaataaatc tctatttcaa aacagcacct
    30481 atatatttaa attactaatt tagtttttac atacttaaat caatagtttt attcaatttc
    30541 ataaattata atacttcaat tataaaacat ttctatccaa caagcataaa tataaagtgg
    30601 gcacatatac ctgcacataa accacctata gtatgcgaaa gtatcgcttt accagccaat
    30661 ggtcttgcat ctaaagcatc catcatacct atgtgtgtac ttaaatatcc actccaacac
    30721 atacccattg ctgtgaatac tgctatatca ttaggagtta tagcgcctga ttttataaac
    30781 tctggtacta aagatattgc tgctccaaca gctcctaatg cagttacagg gaatgctatt
    30841 gcctctggtg atgtgaatcc aaataatggt tctattatga agctaatctt atcaccaata
    30901 gcaggtaata attttatacc ttcatatgca gctcctgtgt aaacagcttg acctgtagca
    30961 gggtctgtag atggtccaaa agttaataac ataactaatg tacaaactac taaaactcct
    31021 ggtattatag ccatacccat ttcaacacct aacttaccac cttcaagtat agcatccaat
    31081 gttctttgga atacattacc atctcttatt tctctaaact cttcaagttt tgcaccttta
    31141 tcatttattt gcttttcagt atcattttta gggtcataat tataatactt tttagtaaaa
    31201 gtcaacataa ttctaacact aataatacta cctattattg ccgcaacatt acctattata
    31261 gctggtagta catattcttt accttgagct atcataaaag ttgttacaat aagtcccata
    31321 ccaaaggctg ttcctaaatt acataaagca ggtacttgat acttcttaaa atattgtgta
    31381 aatgttttgt ctttagcaaa tggtataata gctggattat cagataaata tgttgcaact
    31441 actcctgcta tactagcacc aggtaagccc catataggtc tcataagacc cttaaatatc
    31501 ttattaacta aagatattac tccaaactct gaaagcaatg cactaagtgc acctgcaaga
    31561 actgccatag ccattattaa aaatactgtg tctaataaaa gcgcatgtgc tgtactcatt
    31621 attactttaa acatcattcc tgcacccatg atgcttccta catatccaaa tcctaccgcc
    31681 aatagtacaa taaatacgaa ggtttccata cttactgcct tgactcttct cttatccgac
    31741 agcttttcca tcttgaaatc ttcccccttt taattttaaa ttaaggttcc taacattggt
    31801 acaaattttt tggtacaaac tgagttctaa aacttacact cgtaatgcaa gttgtcagtt
    31861 ttttgaaata aaaaaaaatt acgtttatag aataagaata tcctctttaa tttggatact
    31921 cttattctat tttatgttat tatattatca tccttttgtt taaaagtcaa ttttttctat
    31981 ttttgttgtt taattttatt tatactcttt ttatattttt cattttcttt tatctttgta
    32041 agtactccat ataagttgac ttttctaaat acagtagtta taaataccaa tcctaatgca
    32101 attgaacttg cacacgataa tgtactcacc ccatattcta cagcttttat ataattattg
    32161 gtcaaaacag aatacatagt attatatatt ccataacctg gtactaatat tattaaacag
    32221 caaacactta atgtagttgc tggagtcata taaattcttg cacataactc acaatatatc
    32281 gcaaaacaaa ctgtagctat aaaaaaacat aagttttctg ttactcctat atttaaaaga
    32341 aatttatatg aaaaccaagc tatacttcca cctattcctg ctagtattaa gttttttcct
    32401 ttcatattaa atagcactcc aaagcttaag gcagtaaaaa aagctgctat tacttctata
    32461 aacaaatgca cttatatccc ccctaacttg aagtacaatc caagtaccaa gaacattcct
    32521 actgctatag atacacctac aaaaaatact tctgctaatt ttgcaagacc agaaatcaac
    32581 tgtccatcta acaaatctct taatgcatta gtcaaagcaa gcccaggaac taagagcatt
    32641 attgctcctg ctattaaatg gtctaacgtc tttatgaatc cgagctttaa aattaaaatt
    32701 gaacaagaag ctataataac tgctccaatt gcatttacaa aaaagtcatt aagggaagat
    32761 ttacttaaat acataataac aaacttagtc agaatcccaa cagtaaatgc agctataaat
    32821 tcttccacat ttcctccaaa taatatcgaa aaagttgctg ctgcaatacc tgcaaaaaat
    32881 attgttatta aatctgagta atagttatct tcacttattt catctaaaat tttctcacat
    32941 aattcaatat ctaaattatt tatacttatt gctcttgata atgagttaac ttcatgaacc
    33001 aagtttaggt ctactcttct tgagcttatt cttttaattg ctgaatgtaa tttcccatct
    33061 acaaatacag atgccattac agctgttgga gttgcaaata catctacgtg gtctattcca
    33121 aaagattgac atattctagc tatcgtttct tcaactctat aggtttctcc tccactttgc
    33181 aacatagctt tacctgcatt tgaggaaaag tttaaaattc tatctatatc cacaaaacat
    33241 atctcccatt cttttatagt attattcata ttttaataca agatattatt tatttaaact
    33301 attttaaata attcatatcc aatatttaca ttttatgaaa aaacttgttt tttatgcttg
    33361 tcaaaatcaa attttaagct tgtttacacc ataaaatggc tgaattaata tttgacaaac
    33421 actttcaacc atttatataa ccttctaaat tgtataactt tttactacaa ataaaattat
    33481 atctctttta attctttctc ttgagtattt agcttatagt aacttcatat ttatatatgt
    33541 acaatataaa acattatttt tatgatacaa aatataattt gtaaatgtat atatgtatta
    33601 actgtgtata tataaattat tcttgacctt atcagttttt tcatatatct tcatctatac
    33661 caaccatata ttaataaatg atattacata gacttaagta tattaaaaaa cttaaattta
    33721 gttatttaac aacataatac tctaatttaa tctataaaaa tccatactta atataatgca
    33781 actcttattt taacaccatc tattacacaa aacaacatat taaaaagtaa aatacaaaat
    33841 atccactata aaccttattt taatactgaa tatatattat aatatattta atgtagctta
    33901 aatatagttt aaacataaag aaaggaaacg gtatatgcta agaaaagata aagttctatt
    33961 atctctacat aaattatgtg aaaatatgac tttaaaagac cttcaatcag ataaaacagg
    34021 attcactaca atagaaattg ctaaccattc atctcttgat agaagtaata ccagtaaaga
    34081 attaaataac ctatacaatg aaaaaaaagt tctgaaaata tctggtaagc caattttatt
    34141 tctacatgct agtattatag aaaatttaat tggccgtact ttgaacagtg atgaattttc
    34201 tataaataat tgtaatgagc tacttaaatc aagtaaaaat gactcagaag atattttttc
    34261 aacattactt ggacatgatt ctagtcttaa actacctata gaaaaagcta aatctgctat
    34321 actctatcct ccaaaaggtc ttaatacgtt actaatagga cctactggtg ttggaaaaag
    34381 tacatttgct gaaacaatgt acaaatatgc tgtagaaagt aaaatctttt cttctgaaag
    34441 caaattcgta gtatttaact gtgctgaata tgcagaaaat gctaacttat tattaagtaa
    34501 tttatttggt tatgtcaaag gttcttttac tggtgctaat aaggataaat tcggcatagt
    34561 tgcacaggct gatggaggca tattattctt agatgaaata cacagattgc caccagaagg
    34621 tcaagagatg ctttttcttt tgatggacaa aggcatatac agacgattag gagaatctga
    34681 cattatgcac aaagctaatg tctttattgt gtgtgccaca acagaagata tacattcttc
    34741 tctgcttggg acttttttaa gaagaatccc tgttacaatc aacctacctg ctttacagga
    34801 taggtcttta aaagaaagat tatctcttat taaatacttc tttattatag aatcaaaata
    34861 caccaatgca actataaaag ttcacaaaga tgtaattaaa tcattactcc tttatgattg
    34921 ttttggtaat ataggtcagc ttaaatctga catacaactt atgagtgcaa gagccttctt
    34981 aaattacaaa actggactta aggataatat agaaatagat ttatcccttg ttcctgatta
    35041 catctatatt ggtcttttaa aattgaatga aaatcgtagt aatctaaata aattatcaga
    35101 acttgattat atgctttttt atgaatttaa tggtaataac ttagaagttg aatatacaaa
    35161 agaactatct aaatacaata tagatacatc aaacaatgga tttaaatact ctacagagat
    35221 tccttatctg gaaaatgata taaggagtat gtttataaat tacatggaaa agtactctac
    35281 aaaattactt tcgatatctt cagtaactca ttctgattat acaagtaatg agatttttaa
    35341 agtaatcaat ccaaagattt actatgctgt tgaacattct ttaaaagagg ctgaaaaaat
    35401 atcgagaaac aaatacacaa aacaaactta tattgctctt tcaatgcata taagtgcact
    35461 tatagaaaat ataaatcaag acacatataa tcctaagtac aatttatata atgataaaat
    35521 tttcttagat aaagatttaa atatagctaa aatagtttta agtataattg aaaatgactt
    35581 acaaacatct ttacctaaag atgaagtaaa atttatatcc atgtttctaa atagcatgta
    35641 tcttgaacca aacaatcaat ctgaaagtat aggagtcata atacttgctc atggaaattc
    35701 aacagcaagc agtatgtgtg atgtagcaaa ttcattgctt ggtacaaacc attgtaatgc
    35761 aattgacatg cctcttgatg taaaagtaag taccatactt gataaaacta tagagttggt
    35821 aaaagaatgt gacgaaggta agggtgtact tcttttaaca gatatgggct ctcttatagc
    35881 ttttggagaa cttatttcag aaaaaacaaa aatcaaaact cgctcaattg aaatggtatc
    35941 tactccaata gttttagaag cagtaagaaa aagtacacta ccagaaatga ctttggatga
    36001 attagctaat tccttaagct ctttaaatcc atatattgga cgagcagcaa tcgattcaac
    36061 agaaataaac tatcctgaaa agtcaagaga gtatgtaata ataactactt gtataacagg
    36121 atatggttca gctatgaaag tagcagactt tataaattct tcacttaaaa atattagtaa
    36181 atacaatatt aatttagttc ctcataatat agaaagtttt aaaatgtata agaataaatt
    36241 tagtaatact aaaattctgg cagttgttgg aagtgtagat tttaatgtag ccaacacccc
    36301 ttttatacac atagaggaac tactaaatgg atatggccta gatatgctaa acaaaataat
    36361 agaaggtaca ttcaatgcca atagtattac aaatataaaa gaaacaaatc tatcatacaa
    36421 cagtttaata ataaacttta tgacccaaaa cttagagctt ttggactctg ttaaattatt
    36481 caactatgtc aattcttcct tatttacaat aatagaatta atagatgaaa acttaaagag
    36541 caaatttaag ctaggatata tactacattg ctcttttatg atagaaagat gttttaaaaa
    36601 tacaactttt ccatataata acattactga attaattagt aaaaatcatg aactatatag
    36661 tttaatacgt gaagccttta agccaacaga agcttatttt aatattttga taccagacga
    36721 agaaattgct tatataatag acatgattaa tgagtatcta aataaataaa atttatagca
    36781 cttattttgt gcatattaat taatatatga aatggaggac gagattttga aaggaaaaat
    36841 aaaacagtta acaatacttg cattaatttt tatatttata actcctgtat ttgcatttgc
    36901 agatactcca ccagtaccaa attcttcaag agcagcacta cttatagacc aggaaactaa
    36961 aagaatatta tttgaaaaaa acattgatga aaaaatgcca ttagcgagtt taagtaaaat
    37021 gatgaccttt ttattggcaa tagaagcagt tgataaaaat caagttaaag agactgatat
    37081 ggtgaaaata gacaagtcta cagcttcagt aggaggttct acttgtaaac ttaaagatgg
    37141 tgatgaaata tctctaggag agcttatgca gggtctaatg ctagtatctg gaaatgatgc
    37201 tgctatagcc atagctaaac atattggtaa aactgaaaag aattttgtaa atatgatgaa
    37261 caaaaaagca gaagaaatag gaatgattga tacgtattat tttaatccaa atgggcttcc
    37321 tatatatact gacccagaac ataaagaacc tcctattgaa aatatgtcaa ctgctcacga
    37381 tatagttaca cttggaaagt atatgtacga ccattatgaa aatcaagtta caagaataac
    37441 cactatgcaa gtatataatg atactaaaaa ggattttaca cattataaca caaatcctct
    37501 gcttgtttca gtacctggtg ttgatggaat aaagacagga tatacagata atgctggata
    37561 ttgccttgca ttttctatga tggtacctaa agatgctaaa aacgaaagaa atcatagatt
    37621 gataggtgtt gtacttggtg atggtaacaa gaaaaataga atttcttctt ccgctacttt
    37681 attgaaatat ggtaaagata atttccattc taaaaagata gcacataagg gtgatattat
    37741 agagactcct tgtgttgatg gtattgatga ttttaagata acagttaagg ttgataaaga
    37801 tttgtatggt gttgtttcag ataacgaaaa tatcaatcct aaggtagtgt ttaaaaatat
    37861 gaattatcct atccataagg gagatattgt tggtgttgca aagtattata atgactctgg
    37921 taaatttgtt ggaagtgttg atgtaaaaag tgaaagtaat ataggatgta ttcctttgaa
    37981 ggataagatt aagattaagg ttgctaagat aaataaaaaa cttgagatta aaaattctgt
    38041 ttgttttaaa gcatagtaaa gcatattatt aaaagggtat gttaaattta taaagactcc
    38101 actttgtgga gtctttttgt tttttacaaa aaattaaaat agtggcaaca at
//
LOCUS       DAYAKB010000033        37608 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.033, whole genome shotgun sequence.
ACCESSION   DAYAKB010000033 DAYAKB010000000
VERSION     DAYAKB010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37608
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.033"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(130..324)
                     /locus_tag="ACGI3L_001996"
     CDS             complement(130..324)
                     /locus_tag="ACGI3L_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197705.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(633..2162)
                     /gene="lysS"
                     /locus_tag="ACGI3L_001997"
     CDS             complement(633..2162)
                     /gene="lysS"
                     /locus_tag="ACGI3L_001997"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFG9197706.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2177..2656)
                     /gene="greA"
                     /locus_tag="ACGI3L_001998"
     CDS             complement(2177..2656)
                     /gene="greA"
                     /locus_tag="ACGI3L_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFG9197707.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="ACGI3L_001999"
     CDS             complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="ACGI3L_001999"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFG9197708.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRATEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3870..4640)
                     /locus_tag="ACGI3L_002000"
     CDS             complement(3870..4640)
                     /locus_tag="ACGI3L_002000"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HFG9197709.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4659..5249)
                     /locus_tag="ACGI3L_002001"
     CDS             complement(4659..5249)
                     /locus_tag="ACGI3L_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9197710.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTATSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5432..6400)
                     /locus_tag="ACGI3L_002002"
     CDS             complement(5432..6400)
                     /locus_tag="ACGI3L_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HFG9197711.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6393..7370)
                     /locus_tag="ACGI3L_002003"
     CDS             complement(6393..7370)
                     /locus_tag="ACGI3L_002003"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFG9197712.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7685..9655)
                     /gene="ftsH"
                     /locus_tag="ACGI3L_002004"
     CDS             complement(7685..9655)
                     /gene="ftsH"
                     /locus_tag="ACGI3L_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFG9197713.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIIVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9689..11077)
                     /gene="tilS"
                     /locus_tag="ACGI3L_002005"
     CDS             complement(9689..11077)
                     /gene="tilS"
                     /locus_tag="ACGI3L_002005"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFG9197714.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDGEGIICVGDYKISENYKIDES
                     TKEVLKINFNKL"
     gene            complement(11260..11688)
                     /locus_tag="ACGI3L_002006"
     CDS             complement(11260..11688)
                     /locus_tag="ACGI3L_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFG9197715.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11705..12511)
                     /gene="murI"
                     /locus_tag="ACGI3L_002007"
     CDS             complement(11705..12511)
                     /gene="murI"
                     /locus_tag="ACGI3L_002007"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFG9197716.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12713..13219)
                     /locus_tag="ACGI3L_002008"
     CDS             complement(12713..13219)
                     /locus_tag="ACGI3L_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HFG9197717.1"
                     /translation="MDRWSKLMATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIA
                     KKEVINLSDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQK
                     NAFSVVLDGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMR
                     IGNHVFAK"
     gene            complement(13249..13908)
                     /gene="spoIIR"
                     /locus_tag="ACGI3L_002009"
     CDS             complement(13249..13908)
                     /gene="spoIIR"
                     /locus_tag="ACGI3L_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HFG9197718.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14053..14733)
                     /locus_tag="ACGI3L_002010"
     CDS             complement(14053..14733)
                     /locus_tag="ACGI3L_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9197719.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14717..15607)
                     /gene="ispE"
                     /locus_tag="ACGI3L_002011"
     CDS             complement(14717..15607)
                     /gene="ispE"
                     /locus_tag="ACGI3L_002011"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFG9197720.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15725..17275)
                     /locus_tag="ACGI3L_002012"
     CDS             complement(15725..17275)
                     /locus_tag="ACGI3L_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOCS domain-containing protein"
                     /protein_id="HFG9197721.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVECIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17369..17635)
                     /locus_tag="ACGI3L_002013"
     CDS             complement(17369..17635)
                     /locus_tag="ACGI3L_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFG9197722.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17783..18643)
                     /gene="yabG"
                     /locus_tag="ACGI3L_002014"
     CDS             complement(17783..18643)
                     /gene="yabG"
                     /locus_tag="ACGI3L_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HFG9197723.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18727..19665)
                     /locus_tag="ACGI3L_002015"
     CDS             complement(18727..19665)
                     /locus_tag="ACGI3L_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HFG9197724.1"
                     /translation="MKFLDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19775..19936)
                     /locus_tag="ACGI3L_002016"
     CDS             complement(19775..19936)
                     /locus_tag="ACGI3L_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197725.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19946..20443)
                     /locus_tag="ACGI3L_002017"
     CDS             complement(19946..20443)
                     /locus_tag="ACGI3L_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HFG9197726.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20558..21268)
                     /locus_tag="ACGI3L_002018"
     CDS             complement(20558..21268)
                     /locus_tag="ACGI3L_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HFG9197727.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21444..21974)
                     /locus_tag="ACGI3L_002019"
     CDS             complement(21444..21974)
                     /locus_tag="ACGI3L_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197728.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21991..22221)
                     /locus_tag="ACGI3L_002020"
     CDS             complement(21991..22221)
                     /locus_tag="ACGI3L_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197729.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22236..23630)
                     /locus_tag="ACGI3L_002021"
     CDS             complement(22236..23630)
                     /locus_tag="ACGI3L_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HFG9197730.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23756..25009)
                     /locus_tag="ACGI3L_002022"
     CDS             complement(23756..25009)
                     /locus_tag="ACGI3L_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HFG9197731.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTIPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25060..26214)
                     /locus_tag="ACGI3L_002023"
     CDS             complement(25060..26214)
                     /locus_tag="ACGI3L_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9197732.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGISGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26774..27343)
                     /locus_tag="ACGI3L_002024"
     CDS             complement(26774..27343)
                     /locus_tag="ACGI3L_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9197733.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27546..27773
                     /locus_tag="ACGI3L_002025"
     CDS             27546..27773
                     /locus_tag="ACGI3L_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9197734.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27992..28735)
                     /locus_tag="ACGI3L_002026"
     CDS             complement(27992..28735)
                     /locus_tag="ACGI3L_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HFG9197735.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28903..29775
                     /locus_tag="ACGI3L_002027"
     CDS             28903..29775
                     /locus_tag="ACGI3L_002027"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9197736.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29775..30440
                     /locus_tag="ACGI3L_002028"
     CDS             29775..30440
                     /locus_tag="ACGI3L_002028"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFG9197737.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30461..31318
                     /locus_tag="ACGI3L_002029"
     CDS             30461..31318
                     /locus_tag="ACGI3L_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9197738.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31474..34020)
                     /locus_tag="ACGI3L_002030"
     CDS             complement(31474..34020)
                     /locus_tag="ACGI3L_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197739.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVISKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34020..34706)
                     /locus_tag="ACGI3L_002031"
     CDS             complement(34020..34706)
                     /locus_tag="ACGI3L_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197740.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34789..35778)
                     /locus_tag="ACGI3L_002032"
     CDS             complement(34789..35778)
                     /locus_tag="ACGI3L_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9197741.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35765..36451)
                     /locus_tag="ACGI3L_002033"
     CDS             complement(35765..36451)
                     /locus_tag="ACGI3L_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197742.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36448..36570)
                     /locus_tag="ACGI3L_002034"
     CDS             complement(36448..36570)
                     /locus_tag="ACGI3L_002034"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197743.1"
                     /translation="MDYIRTKETTENCVMISKIVVYYCSAGIYKTNKIKEDESK"
     gene            complement(36951..>37608)
                     /locus_tag="ACGI3L_002035"
     CDS             complement(36951..>37608)
                     /locus_tag="ACGI3L_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFG9197744.1"
                     /translation="SGVPIVDLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMS
                     KLSKVEVSLGPEMKSTGEVLGVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKD
                     EFIEIAKDMKELGYTFVATEGTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIV
                     INTPTKGNDSTRDGFKMRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE
                     "
BASE COUNT        12008 a         6984 c         4214 g        14402 t
ORIGIN      
        1 tttcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt ggttttttta
       61 ataaatataa ttaaaactaa tagatataac ccttgatatt acaaacaata catgcatata
      121 taattttacc tattttgcaa ttttattttc ataagaatat gaattagctc tcactctatc
      181 tgcccaaaca tttatactct taactttatt aacattagtt gtaccctcaa aaatatccat
      241 tgcatcctta caaaaatata tcataacatc aagaaccaaa aatccaacac aaaataaaca
      301 taaaaaatta attacttgaa acatcagaca ttcccccaat aattttttat atatagtatt
      361 ctcataaatt attcttttta ccttctcata aattattcta aatattttca taataaatta
      421 ctttcaatca tattttctaa atataaagtc tcaatcaaca aaaactaata tcaatttcta
      481 acgtttgttg gtaatttata aattaaatat ctaaaagaat ctttgaagca tataaaaagc
      541 attccacact gacattttaa ataaaattta gctatttatt gataatttaa tagctaaact
      601 ttatttaaaa cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg
      661 ttatcaatag gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt
      721 aataacataa ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc
      781 tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt
      841 tttctcaatt ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat
      901 gcattagcta actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct
      961 tcaacatttc tcttagataa tggagatact tcaactggat ggtgagttat aaatgttggt
     1021 tggattaatt tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc
     1081 attccaggtt ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta
     1141 tttatagtag aaaaatctac accagaatat tctttaacac aatcttccat actcattctt
     1201 ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta
     1261 gcaacttcag ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct
     1321 gcatatgctt gatataattc tattgcagta tattcaggat tatgttttaa atccatacct
     1381 tcatttctaa acattcttcc catttcataa actttatcaa atccaccaac aataagtctt
     1441 tttaaataca attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta
     1501 gttataaatg gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact
     1561 tctaaaaatc ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt
     1621 aaaaaagcat tttttacttc tggatttact attaagtcaa catatctttg tctatatctt
     1681 agttcttggt cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt
     1741 aatactacag atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct
     1801 tcaattccaa ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct
     1861 atagcatcta gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag
     1921 ccagctttcc cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttaccc
     1981 tcaagagaat caaagttatc ttttatatcc atagaataat gagttctatc atatctactt
     2041 tctttaaaag gatctctacc tgactcttgt aattttttta gtttatctct tcttacttga
     2101 agtacttcac taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc
     2161 atttttttcc tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag
     2221 gaacttgcac ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag
     2281 attcgtttga tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt
     2341 caacctcttc atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat
     2401 taaggtctat tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta
     2461 aaattctttc ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag
     2521 ataaatcacc aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa
     2581 cctttaagtt ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact
     2641 ctttattttc ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat
     2701 tatattttaa aaattttata atcttttttt aatttatgcg ctatattata agtcactatt
     2761 atttttatgt caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt
     2821 cttctatttt gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc
     2881 aagcgatgtg ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa
     2941 gttttaaatg cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct
     3001 cgcctgtatt catataatgg tttattcttt taaatatcca agggttacct tgagcacccc
     3061 tacctatcat tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg
     3121 taaatacatc accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta
     3181 tatcccagtc tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag
     3241 cacttattcc acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat
     3301 cccagccttt tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca
     3361 atacctcttc tgcaagctta ggatttttca taagtgctga accatctcca tttttaacta
     3421 cttttggagc tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta
     3481 tctctgttgc tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat
     3541 gttcttcctc ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct
     3601 taccatttat catttctgta tataaaagcc cacatccttg ttctttacaa attaatctaa
     3661 atggaaggtc tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat
     3721 ttcctatttt cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt
     3781 cttatttcct cattataata taccacatat agctagaaat ctatcataaa aagggaattg
     3841 gatatataac ccaattccct gtatattaat tattcttggt ttttttcata tattattctc
     3901 aatccttcta gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc
     3961 agtttagcta atccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc
     4021 atcatactta ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg
     4081 gctgatacag tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat
     4141 ttagacgcac tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca
     4201 cccaaatatt cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca
     4261 agtatacttg gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc
     4321 ccaacttgtt ttggattatc atattttata tttagacctg tttttatgcc tggacctact
     4381 attaatggct gttttttaca gtactttata caaaagtttt caagagaatg cataacattc
     4441 ggaactacag atgatattat aacatcatca atatcactta tattcacatt atcataatca
     4501 aataggttac ttatcaggat tccatattca tcagacgttt tttccctatc tgttttaatt
     4561 ctccagtaat taactaattt gtcaccttta tatataccta aaaccatatt agtatttcca
     4621 acatcaaata ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt
     4681 acagtggcaa cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct
     4741 gcggcaagag ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac
     4801 ttgtcagcat ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct
     4861 attgcccctg taattaaacc tgatatgtat accttatttg tagccttaat tattaactga
     4921 tatacataat aagctaatac acctatcata actcttggta atattgaaac taatggattt
     4981 ataaaaacaa aagatgttgc tgttgggttt gttatagcat ttaagagact tgatatccca
     5041 aatataaatc ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact
     5101 ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata
     5161 gatagcataa tagaaatagc tgatagtact cctattatag tcatctttct tacatttact
     5221 tttcttactg atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag
     5281 atgccggact acttaatttt ttaatttttt tcgttttttc ttataactat gagtcaagct
     5341 accattgtag gatgcccgct ctaacaagaa taattttatc aagatgagtt gccattgtca
     5401 acaatttgac aagaaaaata tgctaatttc atcatatttc tcgttttttt actatatctt
     5461 tatatgccat tatattttct acactatccg ctttttttac tgcatttatt atactttttt
     5521 ccacaacctc tacagccaat gaacctacta atgttatatc tgcttctatt tctcctgttg
     5581 atattgtgaa tattgtatct ccatcatgag gtgtatggat aggaaaaata gacttagcat
     5641 atccatcatg tcccatttga gatatctttt tacatccagc tttggttaac ttagcatttg
     5701 ttgcaattat cccaattgta gtattatcta cactaaatcc acctttactt tcaccttgtt
     5761 tcattaattt atatgtatca attgtttctg tctttttatc atttaaagca ccagctataa
     5821 ccttaccatt ttcataaaca tctccaagag catttacagc aattaatgca gatacaatta
     5881 gaccattatc taattttata gaatagctac ctattccgcc tttcatagca tattcctgac
     5941 ctcttatctt tccaacagtg gctccacaac ctgctccata atttccttga tttaaaatat
     6001 cagtatttgc aacttcacaa gctctataac ccatctttaa atctggtcta catttaaagc
     6061 tccctactcc taaatcaaat aaaactgctc ctacaactat aggcacttta cctacaccta
     6121 catcaaagcc aattcctttt tcttctaagt atctacttac accacaagtg gattcaagac
     6181 catatgcaga acctccagcc aaaactactg catgaacttt ttgaaccata tttacagggt
     6241 ctaataaatc ggtttctcta gtacctggag cagagcccct tacatcaaca ccgcaagtag
     6301 ctccttcttc acatattact actgtgcacc cagtaagacc atttctatcc tcaacctgcc
     6361 caacctttaa gccttctata tccaaaatat tattatacat atcctttttc tcctcttata
     6421 gaaacttcac ctgaaataat ttcttttata cttccatcac ttctttgaac taataaattt
     6481 ccctcttcat ttatgtctaa acatttcact agttctctat tatctccttt taatacatat
     6541 atatttttat ctataattgc agaataatct ctacatattt ttaaggtttt ttctttggaa
     6601 ttatttacag tataatctaa atataatttt tcaaattcag ttaatacatt cctaacaata
     6661 tctactctgg ataacatata tccttcttta tacaatgatg tggctttgtc agctatttct
     6721 tgttcaaaat ccattatttt aacatttatt ccaattccaa gaacaacata atttgttctt
     6781 tcaatttcag cagataactc tgttaatata ccacatattt tttttccatt taaaataaca
     6841 tcatttggcc attttattaa tgtatttgct cctagattgt ttaaagcttt cgttacactt
     6901 gctcctgcta ttaaagttat aaatggggct ttgaatggtt ccatatctgg ttttaatata
     6961 atactcatcc agattccttc atgaggtttt gaatcccatc ttcttcccaa tcgtcctttc
     7021 cccatatctt gatgttcact taaaatcaca gtcccatcta cactatttat agctatcctt
     7081 ttagcatgtt catttgttga atctatagtg tcaagatgtt caatattttt tccaataaac
     7141 tctgtatcta atttatagta aatattctgt gggcttaata aatcagttgg attttccgct
     7201 aatcgatacc cttttttatt tacagattct atattatatc cctcttcttt taaggctttc
     7261 atatgtttcc atatagctgc acgtgacacc cctaattgtt ttgataattc ttctcctgaa
     7321 ataaattcag atttattatt taatataatc tctattattt tatctctcat atttcacctc
     7381 taatatgaca taatttcatg acttattttc ttctaataaa taattataca ttattaatat
     7441 acttttaata ctattaattt taaatttcct ttttaattat tataatggtt gttttatatt
     7501 ttatattgat gatttatata attttacatt ttatttaaat aattttaaaa taataaaaaa
     7561 actgaaagta tcaattaaat taatacatgc aaatataatt tgcttattaa tttaatatta
     7621 tactttcagt tttagtattt aatccacatc agataataat cttaaaatga ccaaggtctt
     7681 aaaactattt atctttatca gatttatctt ctaaattttt atttatatca ataacattgt
     7741 ttctttcttc ttcatctttt tctaatttta tagttaattg ttcttcaact tctttagaag
     7801 aattttcctc tgtaactgca ttttcaattt cattcagagg taactcttta ttaaatgctt
     7861 ttacaaattg ttctgcatct aaagtttcat atataagtaa agcttgtgct acatactcta
     7921 atctatccat attttcttgt aatatacttc ttgtcttatc atatgcacca tcaactatac
     7981 gctttgtttc ttggtctatc tcaaaagcaa cttcttcaga ataatttctc ttacttgaaa
     8041 aactattacc taggaatact tcatcatcac tgtcaaatga cattggacca agtttagaac
     8101 tcattccata ctttgttacc atacttcttg cagtagctgt aactctttct aagtcatttg
     8161 aagcacctgt agatacatcc ttaagtacta gctcttctgc tactctacca ccaagtaaaa
     8221 ctataatatt ttctttcatt tcattttttg tagcatagaa cttatcttca acaggaagtt
     8281 gcattgtaaa ccctccagct cttcctcttg gaactattgt aacttgatga acaggactta
     8341 cttcttcaag tacatgggca caaactgcat gccctccttc atggtatgct gtaagtcttc
     8401 tttctttctc acttattact ttcgattttt tagccacacc tgctataacc tttgttatag
     8461 cttcttctat agtttccatc ttaattttct tttctctttt tctagctgtt aatattgcag
     8521 cctcattcat taagttctct atatcagcag gagtaaatcc tggtgttctt ctagccaaga
     8581 catccatttt tacatcatca cttaatggtt tatttcttga gtgaacttta aatatagcct
     8641 ctctaccttt tacatctggt gtaccaacaa caacttgtct gtcaaatctt cctggtctaa
     8701 gtaaagctgg gtcaagtata tctggtctat ttgtagctgc catgattatt ataccttgat
     8761 ttaccccaaa tccatccatt tcaactagaa gttgattaag agtttgctct ctttcatcat
     8821 gacctccacc aagacctgca cctctttttc taccaactgc atcaatttca tctatgaata
     8881 tgatagctgg agcacttttc ttagcctgtt caaataaatc tcttactctt gaagcaccaa
     8941 ccccaacaaa catctcaacg aaatcagaac cacttatact gaaaaaggga actcctgctt
     9001 ctcctgcaac tgctcttgat agatatgttt taccagttcc aggaggtcct accataagca
     9061 ttccttttgg tattcttgca cccaattcaa tatatttctt aggattcttt aagaaatcta
     9121 ctacctcctg caaatcttct ttttcctcat ctagtccagc tacatcttta aatgtaactc
     9181 tagttttttc atcatcttta tgaaccttag cttttgattt gccaaaactc ataacctttc
     9241 cgcctccacc ttgagactga ttcataaaca cgaaccaaat aatcaccatg aagaatatta
     9301 acagtaatgt aggcaacatt tcgacaaacc aaggtgtaga tggcttagct tcaccaccaa
     9361 aagttagttt cccagcctta gcttggtcta acacctcatc tgcaagttta tttcccatca
     9421 cttctgttgg aacatatgac ttaaactttg tatttgtatc ttttatagta ccttctacag
     9481 aagtttgatt tacaaagtat aatcttgata tattctcatc tgttaattct ctatatactt
     9541 cagagaattt taaatctttt attttttctg taggcttacc tgagaattga actataccta
     9601 ctataattat aaaaacaagt agataaaaac ctgccccttt tagcaactta ttcaatatag
     9661 aagccctcct ttcatacatt gctttgccct ataatttgtt aaaattaatt tttaatactt
     9721 cttttgtgct ttcatcaatt ttataatttt cactgatttt ataatctcca acacatatta
     9781 ttccttcacc atctgtgatt ataggaattt tacatctttc ttctcttggg atttttaaat
     9841 ctatgaataa atctttcact tttttacttc ccatagcaag ctttatctta tcaccttgcc
     9901 ttctgcttct tattactata ccccctttta ccttattaaa atcaaaccct ttagatgaat
     9961 tgtctaattt catactctta tacctatcta tgctcattac ttgggtctca ataatttgtt
    10021 ttaattcttt tattttaata aacccattac taggtacatt gtaataaaat tcaatttcct
    10081 cattaacaat ttcctcattc gttaatatta tactgtcttt ttttctataa acaaatatat
    10141 ttcttggaag agttaacatt ttatttactt ttgaattatc ttctaaagac attatatctt
    10201 ctatatgtct ttggtcaaca aaattagtat ctcctagtat atgttttatg gaatttctaa
    10261 gaactctaac tttgatagca tcatgtaagc aaacaaaatc gtctaaattt atctctacaa
    10321 agcctttttc ttttatattt gaaacttctc taaatttagc ttctgcctct ttctcaatat
    10381 aatcgttatc actttttaaa ctattgctca tcctcactat agattctatt acatttgaat
    10441 taaaattatc cttcatatat ggtaaaaggt ctaaccttat cttatttcta gtgtatatat
    10501 tttctaaatt tgttttatct atcctcggat ttaaattata agcttcacaa tactcctcta
    10561 tctcatttct ttccacgtct aatatgggtc taattatgca attatctcta atataatcaa
    10621 ttccctttaa gccttttaaa cctgttcctc tcatgatacg catcataacc gtttcggctt
    10681 ggtcattgag attatgacct attgctattt tattggcttt aatcttatcc ttaatttcat
    10741 aaaacatttc atatcttagc ttccttgctc cttcttctaa tgataatccc tcattttcac
    10801 aatattttgg tacattaata gactttacaa agaatataat tcccatatcc tcacaaagtt
    10861 tagatacata taatgcatct ttttgagctt ctatccctct tatttgatgg tttaaatgtg
    10921 ctgcatatat ttctatatta aaatcttttt ttaatctatt tagtacatgc aataaacaaa
    10981 ctgaatcagg tcctccagaa agacctaaaa ctattttatc gcctttttgt attaaattat
    11041 gtttatttat agtacttagt accttatcaa atatcatatt tatccctctt acacttagtt
    11101 ttattcactt ttaagtatac tttctataaa aaaacgctaa acccttgtat caattttaag
    11161 aaattaaagt ttaatataaa tataataata ccaaataaat taaataaaag gtagtttttt
    11221 cactaccttt ataaaatttc tggaaaatag ccatagttat tatttagtac ctatgtatat
    11281 atctatttta ttcctaccta aaaataaatc ttgtaccttt atattatagt ctattttcaa
    11341 ttttatgtgt tccccttctt gtatatttat atctaattct cttgtatcaa tatcaattaa
    11401 taaagtacct tgtggggtca catactttgt agtactactt tctccacatt taaacagcat
    11461 tgttgagtta atagcaccaa actttttgat actaacttga tttttaagta tctttatagt
    11521 attagttatt tctatatctt cttctttttc cttgtaaata acatatattc catcattttt
    11581 ataaaaaatt ttaccaaagg cagtcatctc tatggtgtcc atatttcctt tttcatcata
    11641 ttgtctagta tttatactta tttttacact caacgatttt tcctccatag attcttcata
    11701 taaactagta tttttgtatt tctacttttt gaatcttatc aatttttttc tttaagaact
    11761 ctcttgctat atctgaaaat ttttcaggta tatctgatac ataatattga taagttccat
    11821 gaatttctgt attgtttata atattttgca cctctaaaat cttttttaaa tcctttgcag
    11881 tctctttagc tggattaaca agttttatat gctctccaac ttcttcacct attgttctct
    11941 ttaaaatagg ataatgagta catcctaaca ctaaagaatc tatatttttt tctttcaatt
    12001 cttgtaaata tatctttgct gtcagtttag ccacttctgt atttgcccat ccttcttcaa
    12061 caataggcac aaataaagga catgctttat taacaatttc tatactctca tctattttag
    12121 atatttccaa gttgtatgct tttgaactta tagttccttc agttcctatt attcctacaa
    12181 ttttgttttt tgtagaactt acagctgttc tagctcctgc ttctataact ccaattatcg
    12241 gtatatcata tttttcttga gcttctttta agcttcttgc agtagcagtg ttacatgcta
    12301 taactatagc ttttacacct tttgttttta aaaagtttat agcttgaaaa gtatatttaa
    12361 ttatagtttc tttggatctt gaaccatatg gtattctggc agtatctcca aagtatatta
    12421 tatcctcatt tggtaatatc ttcattatct cttttagaac tgttaatcca cctaatcccg
    12481 aatcaaaaac tcctattggt ttattgttca tctttataca acacctactt tacatttttg
    12541 tgtttaacaa caacttattt atcgctaaaa tttatattta tattcataat taatatatta
    12601 ttacctaaat gattattata gtttatttta cacaaaaaat aaaggagcta tcttaaatta
    12661 gaaaataatt tctacaaaaa gacaactcct ttcactactt aaaaatttaa atttattttg
    12721 caaacacatg atttcctatt ctcatataag gattcaatct atttatccat ttgcaagtgg
    12781 ctatttctgg attccaaaaa tatactgctt tattagttgg gtcagttcca taaagagctt
    12841 cctgagctgc tttacgtgct gagtctgttg gtgccatctt tattgaacca tcaagcacaa
    12901 ctgagaaagc atttttttga tatatgactt cttctattgt gtctggaaat ctagggtcca
    12961 atactctatt tattactaca gctgctacag caacctgtcc ctcatagctt tctcctctag
    13021 cttctcctgc aaccaactta gataataaca tcaagtcatt atcagataaa tttattactt
    13081 ctttctttgc tatatttttt tcttgtttgt ttactttctt aatattttct gttggttcat
    13141 atgcaaatac ctctttaata ggcataaata taaaagtcaa agctaatagt gtagccatca
    13201 gtttactcca cctgtccatg attaaaacca ctccttacat tcttattttt aaaatttttt
    13261 ctctaaatcc ttgactactt caagtacttt aaacttaatt tttactctac ttgttttttt
    13321 tggtgtatct tgttttatta acttatattc tttatcagtt aaaacttcct tcaacttatc
    13381 atctgtagat ttatctatca ctccattaga ttcatcaaca aaacatagtg gagggaacat
    13441 aacacaccac cagttttttc cttcaccttt cccaataata atctttaatg ctttatattc
    13501 accagctgga agaactatat tagaatattg tttagtaggg aaattgctat attgtatacc
    13561 tacctttaca ctgtaattat atccattttt aagaataata tttttactta tttcttccag
    13621 actactatat tcctttttta taatagcttc actttctttt atactttttg aattttgaag
    13681 ctttggctgt aaatatttta ttacttcatc tctaactttt agtttaagtt cttggtcttc
    13741 atctgtattg ctgtttgcta taacatgaaa tcttattaat ttatctttat aatcttttga
    13801 tatattgtct acttttttta cctcaccatt tattactatt gtcattattg atatgactga
    13861 tataagactt aatattaata gtcccaatct aatcttaatt tttctcattg aaaattcccc
    13921 ctcaagataa atttatatca tcaattatgt ccaattaaat ttaatttatt cataatattt
    13981 tttaatacta ataaaaaaag ctatcttaaa atgattacaa tcattttaaa atagcttttt
    14041 aaaccttata ttttataagt ctttactaat catagcctta tctatcataa actgctctgc
    14101 tttttctata tgctctgtag catacttctt ggatagctca ctatcacctt taattatagc
    14161 atcaagtaaa tatttatgct cttcaacaat attatgtgat gtatcataag cagacatata
    14221 ggtaactcta aatctatata cttgttccca caatgagttt attaattgga ttaatttttt
    14281 attattagtt gctttaaata tacattcatg aaattctaca tcaagtttta ataacgcatc
    14341 tacatcggat tccaaagtgc tttttttaaa ttcttctgat atatctttaa gctttttaat
    14401 atcttcatca ctaattcttt cagcggcaag atatgctgct aagccttcta ggcttgctct
    14461 tacttctaat acatccataa tatcctttaa tgacatattt gccacatacg caccttttct
    14521 aggcaacata acgactaaac cttctaattc aagctttctt attgcctctc tcactggagt
    14581 cctacttact cctaattgtt ctgctagttg cacttccatt agcctttgac caggctttaa
    14641 ttttccttct aagattgctt ctcttaaatt ctcaaagact acatctctta atggcttgta
    14701 attatccaag ttcagtttag ttaaattctc cacaaatttc aacccctttt tgactgctat
    14761 taacaacata cacctgttta tattttttta ataattcttt ttttccaatt agagcatctt
    14821 ctttattttt aaatagtcca aaaactgtag gaccacttcc actcatcata gaacctaaag
    14881 cattattttt catcattact tgttttatat cacttatttc tttgtgttta cctatagtaa
    14941 cattttcaag aatatttacc atgctttctg atacagcttt tatatcttca gattttaaac
    15001 actctatcaa atatttatta tttggtcttt ttttaatatt attcaaatct aatccttgat
    15061 aaacttcttt agtagaaacg aataagtctg gtttgcatat caatatattt gtatcacatg
    15121 gtaaaccttt gatatttgtt agcttttctc caataccttg agctaaggca ggtcttcctg
    15181 atatacaaaa aggaacatct gcgcccaaat taagtcctat ttcttttaat tcatcttcag
    15241 ataatctaag ttcccatagg tgatttaaac ctactaatac tgcggctgca ttagaacttc
    15301 ctccagccat ccctgctgct acaggaatat ttttttctat gaatatttct acaccttttt
    15361 ttatataaaa tttattttta agtattttgg cagctttata aacaatatta tcttcatcta
    15421 aaggaatatc taaactagtg ctttttacct ttatttcatc ttcgtctaat tcttttatct
    15481 ttactatatc gtataaatct atcgtttgca ttatcatttc aacaaaatga taaccgtctt
    15541 gcctttttcc caagacatca atggataaat ttatttttgc tctactcttt agtcttataa
    15601 aatccattct atcctccttg tttaaagaat aatgcatcac taacaataat attatactac
    15661 aaaaaataaa ataatagggt attataatac cctattatac ttaattactt taaatttttt
    15721 aatattaatc tactaatacg actttttttt ctaaaataag acacttccca ggcttaattg
    15781 gttcatcaag ttttatatca ttaagttctg caatttcatt ttctgttgta ttgtattttt
    15841 ttgctatatt ccagaaagta tctccttctt tgcatatata tacgattatg ctaggagctt
    15901 tagataaatc atatacacct tggtcttctc ccttgataat aaaattttct gctttcttat
    15961 ctaatgcttc agtaaatctc ttaattttga taatcaagtc tatctggtcc ctattcaaat
    16021 caacttcgac tttatcaata catgctgtat taaacacaga tgctgtatca gttagattat
    16081 ccatttctat atcatgttca aatggaattt cctcactaat tttataaacc aattttaaac
    16141 cttcaactgg gacaaataaa atttcaactt ttatgattcc ttgtataatg cttttatttc
    16201 cttcaatata actattttct atagacatgg ttggacaaac gcttacaata tcttttattt
    16261 gtatatcatc attatcattt cttatgcctt ctctaaccat aaatgtttct tcactacgtc
    16321 ttaaagtctt atttaattga ataggtttgt ggtcaaattt tattatcttt tgaggcgaat
    16381 atgcatcttg taatacttct cttgtaactt catctgtaac ttttacctta caacaagcca
    16441 tacaatctat ttctaaaaga cctgtgttgc tttcactatt ttgcttgaaa atatgattaa
    16501 aatctgacat agacaacaat acttcttcag tcataccatc actaactcca gggacttcta
    16561 caaattgagt aaactcaata cctactctat ccaactctac aagttcaccc tcatatgtac
    16621 aagctaacgg atttatttct aatactccac caataataac tttattgtca gtcactctac
    16681 tttcttttac tttaacacat ggatttaaac ttattataga ttgaatttcc tctgtgttta
    16741 ttgttatagt atctcttata gaactttctg ctttttctat tccaactata tcttgaaaac
    16801 aaatttcctt tctgtgcttt tgtatgcatt ccacttgcgc cacatctttt acaatgtcta
    16861 acctttgctt ttcaaacaaa cttcccctta tattcataag agctcctact ttaatctttc
    16921 tctcattcat tatagtacaa tccatatgct ctacttctga aaataacatg tattccatat
    16981 cttgaataac attgtctttt tctattactt cgtttatatc tacttttccg tctacattag
    17041 aaatagtatt tttatcatct gcaatataga ttacattata attaaaacta cctctgcaaa
    17101 gtatcttccc atctgccatt tcaatttttt taagtgatat gtatccttct gtttttacaa
    17161 tttcatatac atctaatttt ttgtctggca caactgcctc cgcttcaatg aatgtttgaa
    17221 attttccaaa gtctattcta ttgtcaactt taattacatc tttaattaat tccatagtct
    17281 acctccttaa gtattataaa aatatcacac tatatttata tttaaggagc aaaaaaaaaa
    17341 ttacacctat ttttaaatag gtataatttt aacttatttg taatttatct tgatctctaa
    17401 aaacttgcaa ctttacatta gatgttaata aatctgagta actataagat actctaggat
    17461 atccattact ttcatcatct aactttataa caaacacgct tggataaact ttttctagta
    17521 taccctcttt tgtaataatc tgctttcttc ctttattagc tttcaacaat attttctttc
    17581 ctatatgtct ctctaagctt actcttatct tatctagagt ttgaacagta gccacaatat
    17641 caccttcttt aacgtttata tgtttacata atatcacata taaacatttt tgtcaaatgt
    17701 ttaaactaat tattttatat attttttgca aaaatgtcaa tactattttt gaagatatac
    17761 agtataatta tgttaatttt tgctaatgta atattgtttt tggcattgcc catctaaatt
    17821 ttcctcttgt ttcagaacca ccaattccct taacacctgt aatagtctgc tctataacct
    17881 catcaatagg aactactaca tcaattcttg aacaagcaat tttctccact ataaaaacag
    17941 ggtctaatgc atgtatcatt attcttccag gcgaacttgc atagtttgct cctgcactta
    18001 ttattttttc ataatttgat tggcatgctc ctgcgaatat gacaagatta tccaaatttg
    18061 gttgccattt acgtgcttct tttactgttt taacaaaatt tgaagagttt ctatagttac
    18121 tcatatcttc tatatctcct ctttttattg tcattgcatc atgacctgtt attactagta
    18181 tatccggatt atatttttct agtagtgctc ttacttcttt atactgattt tgctctgaaa
    18241 cagctacacc tactgcaggt attccaagtt gagcatatac atccaagcaa atttttaaat
    18301 attctttatc tccatctatc tgtagtactt ttccaggcat tccatatgtg ttaggattta
    18361 attgaagttt tggaactgct ctagtcattc ttttttgtct ttctttagct tttcttactg
    18421 acttatataa taaattttct acatttttat ctattaatat atcttttata tcaggtgctt
    18481 ttactaattc taggtcatca atataagcat ctgctattac tctaaatgca attcccttta
    18541 gtatagctat tttctcatta ttttcatcta caccaaaaga gactatttta aatactatat
    18601 ctttgttatg tgactttcta gctacaatgt ctcctacctt catagttaaa cctccaataa
    18661 atttttatct tagtttatac tatgttcgat ataaaacttt gtttcctaat gtcaaaaaaa
    18721 catttcttat aatacttctt ttatcactct taaagcattt ttatagtata tcttttctat
    18781 atcatcttca ctaaaccctt ctttttttag aggttcatac agtttaccca tctgagatat
    18841 atcttcaatc tcaacttttg aatctattcc atcaaaatct gaccctagag atacaacatc
    18901 tattcctcca acatttacaa tatgttttat gtgtctaacc atatcttcaa gtttactttc
    18961 acttttatca cttaaaaata agtggaagaa gtttatacct gtaactccac ctttatttgc
    19021 taatacttta atcatatcat cagttaaatt tctagaatga ttcatcattg ctcttgaatt
    19081 agaatgtgta gcaattattg gtttagaaga aatctttgca atttcataaa atccaccatc
    19141 tgaaatatga gaaacatcaa ccaacattcc caattcattc atcttatgta ccacttctct
    19201 tccaaaatca gtaagccctt tttctctata ttctacttta ttatgaggaa agctcaattc
    19261 attcacatga ttccaactta ttgtcatcat tctaacccct aagtcgtaaa atttctttaa
    19321 attttctaat ttaccttcaa gtactgcacc ttcctcaata gataaaagag ctgtaagttt
    19381 accttctgat tggtttttca taatttcttc atagttagta gctaaagcta tttcatcact
    19441 attttttttc atttcctcat gaaatttatt tgccatactc atgcaataat caaaaggatg
    19501 ttttacttct tcagtatcaa caaaaagagc aaatgtttga gctaatgaat cccccttttt
    19561 caatctgtct atatcaacag aatatttatt agacttaagt tcacttgttt ctacattttc
    19621 cattaatttt gctatagtat cacaatgtaa atcaagaaat ttcatattta taccccctgt
    19681 atattttata tttatatcta aaaatagaaa tagttgtcct tatagacaac tattgacaac
    19741 tattttttaa tattcttttt aatattactt aatcttattc ttcttttaag ttaggtatta
    19801 cttttttaac ttcttcaatt tgatgccatg ttttatctat attattttca ctaatatatt
    19861 tttttaaatc agttaaagat gtaaaatctt taactgataa attgtcatca tcatctgcaa
    19921 atcttaaaat aaacatgaga ctcccttact ttccacaaca tttcttatat ttttttccgc
    19981 ttccacatgg gcatgaatca tttcttccta tttttgcttc tttaactatt gttttagact
    20041 tcttataagc ctttattatt tcttttcttt ggtctgctgg tagtatatct tcccaacctt
    20101 gtaaattata tagccaatga gcctcaacag ttaccatatt gttatataat ttttcccaat
    20161 ctatttttat agaaacttct ttatcagctt ctacttcttc taaaactata tcttctttta
    20221 agctttcact tattccatct atgaatccca tgaaaaattc attagtagtt ccaaattttt
    20281 cagccaattc acttacttta ccttcaacaa catccatttt attatttaat atttcattgt
    20341 atattccagc ttcaactttc aaatattctt cccagaattt tacttctgct tcttgacttt
    20401 catgattatc acttaaattt ctccattcag tatataaact catacttttt cctcctaagt
    20461 atacctatat ttttatagtt tttatagtat aaaatctttt agttagattg gaagtttctt
    20521 ctttttgatt ataccatatt ctatttaaag ttaactctta tattatatca taattaaaca
    20581 attcttttaa tacttttata gcatactctt ggtttataaa ataagggctt gtcgcaattg
    20641 ttattacttt ggctttttta attaagtttt ttatcttgta aaatttgagt tcaaatggta
    20701 tatagtccat atcacttgaa aatatatcca aatctatatc aagaacaaac tctgattcta
    20761 cttctaaatc aaatccatat agactatcta ttattattaa ttctgaaaat atgttatatt
    20821 ttaaagcagg ttttataaaa cttcccacat ttaaaacttc atttgtatat ctaaatacat
    20881 cttttagatt atttacatct acatcatagt tctcaggttc tctagtatcc ttatgttggt
    20941 ctacatgcac taacttgcat ccttttgtaa actcaccctt taacaaagat tttgcccaaa
    21001 aataaaatgc atggttatga ttgtcaaaca catatatctt tttatttccc aggacatatt
    21061 cgaccatatt ctccaatcct tttgctttta tttccttatt ttcatctact tcattaaata
    21121 ctacctcatt gcctaacctt acatcattta atgtaccatt tattagtttt ggaacgtata
    21181 tgctcttatt ttctctttta tcatatgaaa atacattatt tcctactggt ttttctatat
    21241 aaaatccact atattcataa ttttccataa aactttattt cctccattgt tatataaata
    21301 tataagttat aattttaaaa attaaaatgc acttattgta aatcatatca tctattatag
    21361 aaaacatctt atataactaa atataatatc ttctctcaat atgtattata caataagtgc
    21421 aaaatatatt tatataaaat atactacatt cctataacaa aaccatcagc ttcaattgga
    21481 aggtaactaa ctcttctatt caactccacc tttccaaaaa atactaccca atatggtcta
    21541 aaaatacttt caattttaac tatttcaatc tctgggattc ctcccataaa cctatgagtt
    21601 aatctcatag ccattttatt tgcctttgct tttactcttc gttcgtcctt atcactatac
    21661 tgcacaatat tacaatccac attttttaca acttcatatg taggaaaatc ttgtactata
    21721 ctaccagaac ctgtagaacc attcactaaa atttttaatt catttatatc attagaatat
    21781 ctcctattct tgaaaatgga tttcgttttg tgaattttaa gtgtgataat tttaaactct
    21841 atataatgaa gtctaacttc atgagcatat ttgttcttta atattagctt actaaataaa
    21901 gaattttttc cacttttagc tatctctata gcttcttctt ttgtaattct tataggtaac
    21961 gctcttatat ccataaaatc attctctttc ttattttttt cttgtcattt ttaaaactct
    22021 atatatataa tcaaaaaata ttacaattac aactgccata actccatatg gaattatttt
    22081 tccaactata atatcatttc tagtcaatat accataaaat ataaatcctg ttattaaaaa
    22141 gtacaataat actagaaaac cgtctattcc aagccatttt atttctaaat ctttttttac
    22201 cttagacact aatttagaca tagcagtttc tccttttata gattattttg tgtatttaaa
    22261 ttttcaccga ttctattacc aatcatccat gcaataaatg aaaaaggtat agctatcaca
    22321 agaggctcta actcaaagct ctgaactgga aatattttaa aataaccaaa agtcactcca
    22381 ccaacaatca ttcctaaaat accacccata gatgttcttc ttccatttcc aagaagccca
    22441 cctactatag gtacaaatgc cgaacccatc caaatacttc ctacaaatat acatgcatca
    22501 tatacatttt caaatctaaa tgctacgcta agccccataa ctgctgctaa acatacacct
    22561 attctagtaa actttactaa ttgtttctga gataactctt tttttgtaat tcttccatat
    22621 atatcatttg ctaatgtagc cccagctgct agataatagc tatccaatgt tgatattata
    22681 gaacctaaaa ttcctattat aaatattact cttattcctt gtggtaatgt atctaaaact
    22741 aaagttatat atccagcagc tggagccatt tctggataag tagctcttac tataagtcct
    22801 gtcatagtta acaccatgtc aaaacatatc catagtgaaa aacaggttaa taaggctctt
    22861 cttccaacct taggagaatc tgctgctgaa aatctttgat aaaaagttgg gtctgaataa
    22921 gctccaaaag aatatacaat taacatcaat gctttcatag ctgacatacc ttttgtaggg
    22981 tgcataagct gtggtgcatc tttgagtgct tctgtaagac cttgaaaccc tcctatttgt
    23041 tcaaattgac ctggcataac catagttaaa ccaaatacca tacaaaaaaa caataccata
    23101 tctgtaatgg caactcccat aagcccacca agtactgtaa gtacaacgac tactcctacc
    23161 attattaatc ctattaattc tttatctatt ttccatgcta cgttacctat agttcccata
    23221 gcagttattt ctccaagttg tgcacaatat ataaacatca aaattgcccc aattatagca
    23281 acatgcttgc cataaaaact ttccagtaaa tcaggaactg ttatattggt tcttatatga
    23341 atccttggac caacccacaa tgctaaaggc attctcccaa tatgtgcagc tattgaccaa
    23401 actgcccatg cagatattcc atatatagcc gcatactcta cactacctac tgtaccaact
    23461 cctccatacc atgatgcaac caaagttcct actattaagg accatggtaa acttcgattt
    23521 cctaggtaat aactttccat atcttttaca tttctagaaa aataataacc tattcctaat
    23581 aatataaatg caaatataac tataatccca ttttcccaaa atgttaacat atctaatctc
    23641 cacattctta tattttaatt tttaacttta atatctaaat atgaacaact ctacccattt
    23701 ccataaaaat aggtagagtt atataataat tataagtatt taagtaatct tgttattaag
    23761 caattttatt gtttaaacct ttattttctc ttttatttat tttatttaaa gcataagtag
    23821 caaatatccc tataactgca catactacag ataaaataaa tatatatgta tatcctgttt
    23881 gtccatattt atctaaccaa ttacctgcaa tagtgtaata aaacgcatct ggagaaaatc
    23941 ctataaatga agcaaatcca actactgctc ctgtagtttc taaagatata ttagactctg
    24001 aaacagatgc aaagtatata cctctaaatc caaataaaat tacacttagt attatcatgt
    24061 ttattacagc tatccatata aatcctgtac tcttaggaat aaccaagtaa gcagctgtac
    24121 ttactgtcat taatataaat cctacaaaca ttactcttat agatgaacca actttatctg
    24181 ttataacacc agcaactgga gatgctccca tttttataac ataagttctt attattgata
    24241 aagcagaaac tagagtcatt ggcattacat aaacttctga taagtatgga cttaaataag
    24301 ttaaacttga gaatactaaa taagttgaaa atattataag accaattaac caagcctttg
    24361 gtattgtaac tacttttaac aatgacttaa tacttaatcc ttcatctgat gctccactat
    24421 cttttttctc ttccactaag aaaaatagaa gtataccaca tattatagat gctgcagaat
    24481 ataaccatac tacatatttg aatcctactg ttatttcagc aaatttacca aagaaataaa
    24541 gacctataaa agaaattaat gtacctgata cacctgataa cccttcataa aaaccaaata
    24601 ttcttccttg ctctgactca cttccttgca ttctaacaac cttaacagag gctgagaaga
    24661 aggttaatat tgtcgtaaat ccccataata caaatattaa aagtatcata ctatatgatg
    24721 ggaatgtaga gaaataaaat ccaagtatcc ctgaagcaat taaagaaaaa gttattaatt
    24781 ttctaactga gaatctatct gcaaaccatc ctcctataaa ataagatacc attcctacta
    24841 atccatataa actcaataag ttccctattt gtgtatgact taatgctaaa gcttgttgca
    24901 ttgggtcata aaatgatgat ttcatatatg gtaaactata catagctgtt gttccaaatg
    24961 ccaatatgaa tattatcaaa aatcttttaa cattattttt gctttccatt gattctctct
    25021 ccttaaaatt ttattgttta taatctcatt catataattt tattttaatt tttctattgc
    25081 ttgtttaaaa tcatttatta tatcatttga agattctaat cctacagcta ttcttattag
    25141 attttcccca ttcatttgaa ctaatgtatg ctcttcccct aagcttgttg ctattgttgc
    25201 aagctctaaa gagttcatta atcttctact agcttggtct cttgtcaatc cactgatacc
    25261 atccttaagt ttaaatgaaa ctacgcctcc acctaaacca ttcatttgag ttttacaaag
    25321 ctcatattga ggatgtgatt ttaatgctgg atactttacc aattccacat tctcttcttc
    25381 ctctaaaaac tctgctactg ctaatccatt ttcacaatgc tttttcatcc tcatatctaa
    25441 cgttttcata ccccttaaaa tcatccatgc actcattggt ggtaaagatg ctcctgtaaa
    25501 acaacataaa cttggccatc taactaaatc tattaattct tttgaacctg ctactgctcc
    25561 ccctaaagta tctccatgtc catttataaa cttagtaaga ctatgtatta ctaaatctgc
    25621 acctaaatct attggtcttt gtacaattgg tgtcccaaaa gtactatcaa ctatagctaa
    25681 gcttttattt tcatgagcaa tttctgctat tgtttttata tctactaagt ctaatgatgg
    25741 atttaaagga ctttctatat aaactatttt agtatttggt ctcattgctt cttttacatt
    25801 ttgtggattt actgcatcta caaatgtaac ttcaactcca aatttagata acaactcaga
    25861 catgaataat ttagtgtgtg aaaatattcc atctgaacta actatatggt caccactttt
    25921 taccaatgct aatatagtag atgttattgc ccccatgcct gatgtactag atatggcact
    25981 ttctgcattt tcaagcatag ccaacttagc ttctaactct gtaagagtag gattacactc
    26041 tcttgtatac acatatcccc atgtcataca caactcttca aaatgctcta ctgtctttgc
    26101 agcaaatgtt gctgtttgac atattggtgt agccaatgca cctgttgttg ggtctgcact
    26161 atgtccccaa tgtattattt ttgtctctaa atcttgatta atattgttac tcattttgat
    26221 ttcctcccat tttgacttat ttatacaacg ttttccctgc caaatttcat caatttagct
    26281 tagtcttaat acattttttc aagtatactt ttttatttgt tataatttct aaaaatatga
    26341 cacttatttt gtttttttac agttctaatt ataaactcta tagtaactat agagtcaata
    26401 tgtttttgat atttttttta caatgtttaa aatagtcaat acaaaaatag gtatatctta
    26461 gaataactaa agtcatccta agatatacct atttttatat cacaatataa ataattacat
    26521 ataagcatta gtttttttat cataaataga tttttcaaga tttatcattt tttcataaat
    26581 atattatagt taaatatttt aatattacct aacatctaca ataaaatata ctcttaaaat
    26641 aaaattatat aattaaaaat actctataaa agctaaaaag tttttctatt cgctacatct
    26701 aaaaataatt agatagaggt ataaatgtat ttagtttatt tatacctcta gtcttttata
    26761 aattatatct ctactaaatt gattttttag cacgaataag tgtgctcttg gagataccag
    26821 tcatcttcac aacctctcta tatggcttag aatttaataa ccccaatgca tattgtatct
    26881 gttgattgct gtatttcttt ggcctaccat ctttaaagtc ctttttcttt ttagcaaatt
    26941 cttttcctaa ttgagtacgt tctattatca tatttctctc aagttctgca actgcaagta
    27001 atgtagtcaa aaagaattta cccattgaag tattttctaa aaggcctata tttaaaatat
    27061 gaacacttac ttctttagca aataaacctt ctattagttg tattccttct gatgtacttc
    27121 tagctagtct atccagctta gttgcaacaa gtaagtctcc cttttttaga gatgatataa
    27181 ttttttcaaa tttaggcctg tttgtagtag tgcctgtata agtttccttt attattttag
    27241 catcattata tttattcaaa atttcttgct gttgctgata caaactgttg ttgtctgttt
    27301 gattttttgt acttacacgg caatatccat atataataat catcacttcc taacataaag
    27361 attttgtaca gaagttaccc agaagcttgt ttttacttat ctttatccat tttactaaaa
    27421 cgatttttgg gtgtcaatac tgttaacttt tgacaccata ataattcctt tataatttgt
    27481 ttgactatgt caaaaattac caatataatg aaattaatga gtttatacaa attggaggaa
    27541 ataatatgaa tagtctgtta aaagaagcaa tagatgaatt aaaaaacatc cattgcgggg
    27601 aagttttttt attaaaagaa ttgttcaaag gctatgaatg gaacaggttg gagatgaata
    27661 tcagattgaa attaggaaaa ctttttttgt atgaagtggt aactaatccc aatttaaatg
    27721 tagaggtcat caataaaaat tctgcttatc agcaaatgta taaaaaaaaa tagtgactta
    27781 aatgtatata atagtataat cttcttattg attcaaaagt taaaactttt aatacaaaac
    27841 aatcattcta ttttaacatt tatcaatatg tctaaattta tataattaac acatacgaat
    27901 agtattgttt aaatcacatt atttaagata gataaatctt aaccctactc cagcataaat
    27961 actaaaatag ggcttagaat tatctatatt tttatcccat aaaatgctta gctcttcctc
    28021 ttgattgaac atatatatct ggggaaatac aatagaagcg taaatttata aaatttccaa
    28081 agtcagaaaa cttcagttca aacttaggta taccaaaact ttcaggtgct atttcgtcaa
    28141 cgccaaaata gatgataatt ccattatctg taagataaaa tgcttggtct tcaggtataa
    28201 ctaactcaac attagaataa tacatttctc tattttcatt tatttgagat ttaatgtaat
    28261 cagtaattat attaatataa tcaactccat ctctaaaaat gtcattaagt aaaagttctt
    28321 ttccagttgt caaatctata ttgtaattat tcaatgtatt gtatttaggc ccatagttat
    28381 tagcaaaccc cataaggttt aatatcatac tcagtacata atttttatta aaagtaactg
    28441 cgtaactggt agatacccaa tagctttgtt ttggaagtga attttgagaa gctgcgttat
    28501 tatattctcg ttcttcttcc tgtaagccat ttttaaaatt atttacagtc attcttacag
    28561 cattgtttat gttatttaaa ataactgggt ttacatacgt ggattgattt ctaatattgt
    28621 atataacagg atactttaca tcatatgaaa aatacttact tctttcaaaa tcttcattaa
    28681 attgtacata taatatatta tatgtacagg tatttgtaga ttgataattt tccattaaaa
    28741 tcctccccct tttataaaaa aatcagatac aatataatat gcttaaaaca gtaataatgt
    28801 taatggtaaa tgtaaagaat agaaagtatc taaaacagca aaaaatgact aattttgtgg
    28861 tataatacat aggattgaga gttattttat aggaggaaaa atatgttatt attagcagat
    28921 aaatggaaag attatgaact tatagatatg ggaaatggag aaaaattaga acgttgggga
    28981 agttatgtac ttagaagacc agacccacag gttgtatggc caatggaatc tgaatgggct
    29041 ttatggaaaa accctcatgg acattatcac agaagcaata aaggtggagg tcaatgggaa
    29101 cacaaaaaaa gatatccaga acaatggact ataaattata aaaacttaaa gtttcacatt
    29161 aaaccaactg gctttaaaca tactggatta ttcccagagc aagcagctaa ctgggattgg
    29221 atgatagaga aaataaagaa agctaacaga cctataaaag tgttgaatct ttttgcatat
    29281 acaggtggag ctactgtagc atgtgcatct gctggtgcag aagtatgtca tgttgatgct
    29341 gcaaaaggta tggttaattg ggcaaaagaa aatatagaat tatcaggtct taaaaatcaa
    29401 acagtaagat ttatagtgga tgatgttgta aagtttgttg aaagagaaat aagaagaggt
    29461 aaaaaatatg atgcaataat aatggaccct ccttcttatg gaagaggtcc taaaggagaa
    29521 gtatggcaaa tagaagaaaa gttatacagt tttgtagatt tatgtatggg agttttatca
    29581 gataaccctt tatttttctt aattaattct tatacaacag gattttctcc aatagttctt
    29641 gaaaatgtat tgtctacaac aataggtaaa aagacaaata caggagatat atacggtggg
    29701 gaattaggaa taccagcttc cagagatggt aagatacttc cttgtggtat atttggaaga
    29761 tgggagaaaa aataatgata aaagtcatat atgaagataa ccatttatta gttgtagaaa
    29821 aaccagttaa catattgtct caaggagata atactaatga taaagatatg gtaaatcttt
    29881 taaaagacta tattaaaaaa aagtataaca aacctggaaa tgtatatatt ggtttaatac
    29941 atagattgga tagaccagta ggtggagtta tggtgtttgc aaaaacatca aaagcagcat
    30001 ctagattgtc tgagcaggta agaagtaaga ctttcaaaaa aacttatcta gctgttgttc
    30061 atggcaagat aaaatctaac tcagatatac taaaagattt tttatataaa aataaaaaaa
    30121 ctaatatggt aactgtagtg aaaaaaagcc ataaagatgc caaagaagct gaacttaact
    30181 ataatgtatt agattttaaa gaaaatctaa gtttagttca agttaattta aagactggtc
    30241 gttctcatca aataagagtt caatttgcaa gcagaaaaca tccattatac ggagaccaaa
    30301 gatatggcaa agaaataaat aagattggac aacaaatatc tctttggtcc aataagatag
    30361 aaatttgcca tcctactaca aaagaaaaaa tggaatttac atgtcatcca cctgacaaat
    30421 atccatggaa tatattttaa atctcaaatg aggtgattat atgagtaaaa aattttcaat
    30481 aggagaaatg tctaaacttc ataaaataag catacagaca ctaaggtact atgaccaaat
    30541 agatttattt aaacctgttc atgttgacca agaaagcaat tacagatatt actcaattga
    30601 ccaattttca caattagata ttataaaata tttaaaatat ttaggtatgc ctttaaaaga
    30661 aattaagtca aagcttgatg aaaataatga agaaattcta aaattactaa caaataaaat
    30721 taatatagtg gatgaaaaaa ttaaagaatt agagcttata aagaaggtac taagcacaaa
    30781 gaaagaaact atggaaaaag gtatgaaagt agatgaagtt ggtaaaatag tgagaaaaca
    30841 tattccacga agaagtatct tatctataga gtatgaagaa ggattaagta gtgaagaaac
    30901 tatggaactt tccagaagac aaatagcaaa tatattagaa gataatatat ctgtgttcta
    30961 tggtggagta agtggacttg tatctataga taaattttta aaagaagata aagttattta
    31021 tgacaatagt tttgttactg ttgaaagaga cttatttgat ataaaatcac aaaaacatat
    31081 aacagaaatt tcatctggtg attttatttg tatgacatat aaagggcctt acaaagaaaa
    31141 ttataccgct tttaagaaac tggttgatta tgttgaatat aaaagaatac ctattgaaaa
    31201 ttatatatat gaaataccta taatagaccc tctgtctaca aacaacgaag aggaacttct
    31261 aacagaaatt caaatacaag ttaaaaagag agaaattgac ttaagatgtc tagtgtagta
    31321 atctagttta cttacacatc ttaatatagt tgtctattat caacatatga tttttctaga
    31381 tagtgattcc taacagtgag attttcaaaa aataggagga aatatggcta atgctaattc
    31441 cctcctattt ttaattaagc catatcattt taattaagcc atgtcatcac gaagtgcatc
    31501 aataatattt tcttttttta tcttattaat agtatacaac attgtaataa atactataaa
    31561 taaaacacta aatatactaa ttccaatact aaaccatgga atcacaaaat caatatcatc
    31621 tgtaaccatt actttatgaa ttagccatga agaaattact gctataggaa gtccaaagaa
    31681 caatgctctc atgccataaa aggcacactc aaaattcatc atcttttgga aatcatgctc
    31741 agacattcct acagagcgaa gcatggcaag ttctctacga cgtaacttaa tattagttga
    31801 aattgtatta aacacattgg caatcgaaat cagagaaatc ataattatga aagtataagc
    31861 aaaaacattg gcaataaaaa tgtaattacg gttctcatcc atcattccat acatattgta
    31921 cagattgtac tcattcgtaa ctccctcact ctcaataatt tgctccattt ctgcaactga
    31981 ctgagtagga tttttcgatt gaaagcttaa actttcaatt cctgtagaaa caccaggaat
    32041 ctcaaactta tctttggctg aataaggagc caatactctg aagcttgctt tcttcacatc
    32101 tgaacttctg attcctggag gagaatcagg tggcactact ttgacaaatg aaatattcac
    32161 attttgtctc tcaggtatct ccaacttgcc attagtttca ggagtgaggc taacattcat
    32221 agaagaactg ttgaaaatat caataatatt attatccttt gttaccatag aaacagcaat
    32281 cagttttgca ttttgtccag tatattcttc tgctggtaat ccaagacttt taataatatt
    32341 cagataagtt ctatcatcaa gaaattgcat atctactggt aattcaagca tttcactcat
    32401 agaatgtgaa ccctcatagt tcaaataatc gtctgtaagc tcacttactt tggcaacaca
    32461 tgaataggtc ataagtttct gatacaaacc ttcgtaaaca ccatttgcag tttttagctt
    32521 atcgtaaagc ttcaacattt cgttgtcttt cataccttgt gtagaaaaaa taatatcctg
    32581 gtcagtaacc tctgacctct gatttgacat ctgttttagg tctgctacta aagcacttgt
    32641 agatataaat agaactatgc ttaaaacaag cgacaataca atacttcgat aacgtttctt
    32701 gtttctttta aagtttttca tagcaagaac tccctcaaga ccataaactc gctgtgttag
    32761 ttttgatgtc ttcacagatt tagattcaat ttttacctca tttgtctgac gaatacactc
    32821 catcactggt gtgttggcag cctttcttgc tggtatgtaa gcagaaatta agattgtaac
    32881 catacttacc actgctgcaa cgatgattgc agggatagac aatgttaatg tcaacggaac
    32941 gtttacatag agaatatttg caaagttttt agatatgaca gaaatcacaa gtccaatact
    33001 gactataccg attgcaacac caattggtat accaatcgca ccaatgcaaa ttccttcaaa
    33061 tagcaccgaa tttcgtaact gttttgctgt agctccaaca gatgaaagta ttccaaattg
    33121 atgtgttcgc tcgttcaatg acatgttaaa tgaattatat attagaaaaa ttgagcctag
    33181 catgattatg gcaagcacaa tgccaccaac cgagtacaaa aacatattga acaaattgtt
    33241 atcagagaca cctatgaatc gcaacacatt gtcattgaaa atggaagcat ggtctttagt
    33301 gctacttgtg taagagcgaa tctgatgtgg atttttcaat gtgacaaaaa ggctaagact
    33361 gtcagtcttg acttgtttat cttctttggt tatcaaggta tatcctggtg cagaagattc
    33421 ttcaaatacg ggctttctac agatacccac aactgtataa gttttcttat cctgtggcac
    33481 aaaaacttca ctcccagcag tgtatgggtc actctgacca agcttttcat tttcactcat
    33541 tcgtttccct acatccaaag aaatagtatc ccctactgca aatttgacac caccatctgt
    33601 cgcaacttta cttgaaacaa gaatctctct actattttca ggtaatcttc cagaaattaa
    33661 agttataggc aaagtatcaa aagcttcttt gctaaatcca gcaataaaaa gatatggttt
    33721 atctggattt ctgttacctt caagtgttgc atagccaata ttttcaaatg ttgcagtatt
    33781 tgcaacttca tcattgactc tttgttcctg tacaaaagaa gaatccacat ccaaaaactg
    33841 gacatgccaa tcaccatatt ttataatagc tccatttatc atatagttca tcaaagaaac
    33901 tccaaaggta gtaactgctg taatcatagc agctgacaga acaactccta taattgttac
    33961 aagagttcga gttcgattct ttttcaatcc ttgcagagca actttgttaa aaatgttcat
    34021 taacgattca ccttcctctc atcacgcact acttttccat ctgaaataca gataattcta
    34081 tctgcctgta aagcaatgtt ttcatcatgt gtgacaataa tgagagtttg gtgatattta
    34141 ctatggctct ctttcagtaa ctggataatc tcttgtccat ttttactgtc taagctacct
    34201 gtaggctcat cagcaagcat aactgctggt gcattcatca atgcacgacc aatggcaaca
    34261 cgttgctgtt ggccaccaga aagttgattt ggtaaatgtg tttttcgttc ttttaaacca
    34321 agtaattcta acaagtcatt taaccgttct tgattgacct tacgcttatc cataagtata
    34381 ggcaatgtga tattttccac tacatttaat gtgggtatca gattgtgaaa ctgataaatc
    34441 aatccaactt gtcgcctacg aaaaatagca agtttttcat tgctttggcc atatacatct
    34501 tgcccctcca gatatatctt tccacttgtt ggtacgtcta ctcctgcaat ggaatgtagt
    34561 agtgtagatt taccagaacc agaagaacca atgattgcag taaactcccc tttttcaata
    34621 gtaagtgaga catggtcaag tgcagtaacc ttattttcat tcttaccata aaccttacat
    34681 aaatcttcaa tctttaaaaa cgccattata taagtctcct ttcatatttt ataaatatat
    34741 catagaactt tcaacttaca tttaagtgac atttaaatga gagattcgtc actttggaaa
    34801 acgaataaca aatattgcac caccttgtgg gtgattttgt gcagtaattg ttcctccttg
    34861 tctcataata atcgtcttac aaagtgccaa tcctattcca taaccggctg tgcttgaatt
    34921 tttcccacga taaaatctgt taaatagaca tggtaaatct tcttttttaa agcctgctcc
    34981 gttgtcatga atagtaagtt gagtaaacaa aaagttgtcc tcacaaatga tatcaatttt
    35041 tccattatca cccacactct ccatgcagtt tttaaatata ttttgaattg cttctgaaag
    35101 ccaatttaaa tcacccaaaa tccttactcc ttttggtata tcaatatgta aagtgatatt
    35161 gtgcagttcc atgggaatca aaagttgatg aagtgcagaa ctaatcaaat tattcacatc
    35221 aatttgttct ttttgaaaga ctacaatacc tgcatctaaa cgtgataatt ttaaaaggga
    35281 agtaatcagc cagtccattc gtataagtaa ttcctctgtt tctcgtatca actcttttct
    35341 ctcatcttca tcagaagtat tctctaacag tgacaaaata agagttactg atgtaagagg
    35401 agtgcgaagc tggtgggcta tgtcagctag tgagtcagca aggtgttctt tttctttttt
    35461 cagtgcgtaa ttttgctctc taatgcgtaa cgtcatttta gttatttcac tttgtagaat
    35521 agaaagctca ccctcatctg attcagcaat atacagatgg ttagcattat gaagcacaag
    35581 attaatttgt tctgaaatct gtgcaatact tttgtatcga tttttagtaa acacaaaaaa
    35641 tgctattcca aaggtagtgg cagaaacaat agaaagtatt ccagtcataa tactgattgc
    35701 aaatcccagg gctacagtga gaatagtaat taataagaat aaaatagcaa attttcgaaa
    35761 ctctctattt cgaaacataa cttcccccca atctataccc tgtcccacga acagtcaaaa
    35821 ttatttgtgg acttgaaggg tcatcttcta tcttctctcg caagcgtttg atgtacacag
    35881 tcaatgtgtt gtcattaaca aactcacctg ccgcatccca caattcatca agtaatctta
    35941 ccctcgtaat aatactttta ggattgctaa taaacaccaa taacaaacgg tattctaaag
    36001 ctgaaagaaa aacctcattg ccattctttt tcacaacacc agttgctgta tctacataaa
    36061 gcccacaaat ttcaaaagtt gacccaaaac gcccactttt tcgtagtgct gttctaattc
    36121 gcgcaatcag ttcacgtgga cgaaaaggtt tagtaatata atcatctgca cccatattca
    36181 gtccagtaac aacacttgat tcatcaccgg aagctgtcaa aaagataaca ggaatgtctt
    36241 gcttttcttt gatttctgtg caaatcgtaa acccatttcc atcaggtaaa gaaatatcaa
    36301 taagtgccaa atcaaattta ttcttagcaa tctctacaag tgcttcactt cttgtggata
    36361 catgggttac tataaatcct tctgaattaa gcaaaagaat aagatttttg gcaattgctt
    36421 tatcatcctc aactaaaaat atccgtttca tttactttca tcctccttta ttttattagt
    36481 tttatatatt ccagcagagc aatagtacac tactatttta cttatcatta cacaattttc
    36541 agtagtttct tttgttctta tataatccat gcataatacc tccattgatt tattatattt
    36601 cttataacat aaatacacaa gataagacaa aaaacataat gtaagtgcaa gttttttaac
    36661 tcactaactt ataaacatac actcctacta acactacttt cttgatgaca catcttacaa
    36721 gcttatattc atacatcaat gaaaaattaa atttatccat ttattaaaat aaaaggcaat
    36781 agcttctata gctaatgccc tttatcttaa aatgatttaa atactataca atttttataa
    36841 atggctataa ataaactcgt atagaatata aaatttatct acagtctttt gttatacaaa
    36901 atttataacc tcttatagaa caaatttacc actttgcaaa cttatcactt ttactcagct
    36961 atattataaa cttttaattt atctttgttt aaatgtttct tcttaacttc tactaaagct
    37021 tttagcgtat ccaaagatgt cattatttca gtagaaaatt caatggctgt tcttctcatc
    37081 ttaaatccat ctcttgtaga gtcatttcct ttagttggtg tatttattac tatatcaact
    37141 tgtttatttc ttatagcatc taatatgttt ggtctaggtt cttcaattct atttactata
    37201 tcagcctcta ttccattttc tcttaaactc ttcgctgttc cttctgtagc aacaaaagta
    37261 tatcctaatt ctttcatatc ttttgctatc tctataaact catctttatc atgattattt
    37321 acagtagcaa gtactactcc tctttcatca gacatatgtc tacctgctgc caagaaccct
    37381 ttatataagg cttcttctaa attttctcct acacctagga cttctcctgt agacttcatt
    37441 tcaggtccta gacttacttc aactttagat aatttagaca ttgagaatac tggtactttt
    37501 actgatacta attttggctc tttgtaaact cctgtaccat atcctaaatc ctttaattta
    37561 gctcctaaca tacacttagt agccaagtca actattggta ctccactt
//
LOCUS       DAYAKB010000034        36040 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.034, whole genome shotgun sequence.
ACCESSION   DAYAKB010000034 DAYAKB010000000
VERSION     DAYAKB010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.034"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            129..791
                     /locus_tag="ACGI3L_002036"
     CDS             129..791
                     /locus_tag="ACGI3L_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFG9197745.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            1162..2571
                     /locus_tag="ACGI3L_002037"
     CDS             1162..2571
                     /locus_tag="ACGI3L_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFG9197746.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            2686..2961
                     /locus_tag="ACGI3L_002038"
     CDS             2686..2961
                     /locus_tag="ACGI3L_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HFG9197747.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            3591..3902
                     /locus_tag="ACGI3L_002039"
     CDS             3591..3902
                     /locus_tag="ACGI3L_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197748.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            3904..5829
                     /locus_tag="ACGI3L_002040"
     CDS             3904..5829
                     /locus_tag="ACGI3L_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFG9197749.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFNCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            5832..6323
                     /locus_tag="ACGI3L_002041"
     CDS             5832..6323
                     /locus_tag="ACGI3L_002041"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFG9197750.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            6375..6938
                     /locus_tag="ACGI3L_002042"
     CDS             6375..6938
                     /locus_tag="ACGI3L_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HFG9197751.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            6953..7930
                     /locus_tag="ACGI3L_002043"
     CDS             6953..7930
                     /locus_tag="ACGI3L_002043"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HFG9197752.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            7923..8240
                     /locus_tag="ACGI3L_002044"
     CDS             7923..8240
                     /locus_tag="ACGI3L_002044"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFG9197753.1"
                     /translation="MYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVEDEY
                     AIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGADIL
                     FKE"
     gene            8357..10135
                     /locus_tag="ACGI3L_002045"
     CDS             8357..10135
                     /locus_tag="ACGI3L_002045"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFG9197754.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            10132..11505
                     /locus_tag="ACGI3L_002046"
     CDS             10132..11505
                     /locus_tag="ACGI3L_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFG9197755.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            11511..12179
                     /locus_tag="ACGI3L_002047"
     CDS             11511..12179
                     /locus_tag="ACGI3L_002047"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFG9197756.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            12456..13505
                     /locus_tag="ACGI3L_002048"
     CDS             12456..13505
                     /locus_tag="ACGI3L_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9197757.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            13601..14590
                     /locus_tag="ACGI3L_002049"
     CDS             13601..14590
                     /locus_tag="ACGI3L_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197758.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKGKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDASIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            14595..16313
                     /locus_tag="ACGI3L_002050"
     CDS             14595..16313
                     /locus_tag="ACGI3L_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HFG9197759.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAASLAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(16395..17549)
                     /locus_tag="ACGI3L_002051"
     CDS             complement(16395..17549)
                     /locus_tag="ACGI3L_002051"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9197760.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            18048..19409
                     /locus_tag="ACGI3L_002052"
     CDS             18048..19409
                     /locus_tag="ACGI3L_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9197761.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            19500..20204
                     /locus_tag="ACGI3L_002053"
     CDS             19500..20204
                     /locus_tag="ACGI3L_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9197762.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDVRVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            20404..20715
                     /locus_tag="ACGI3L_002054"
     CDS             20404..20715
                     /locus_tag="ACGI3L_002054"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9197763.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            20737..22050
                     /locus_tag="ACGI3L_002055"
     CDS             20737..22050
                     /locus_tag="ACGI3L_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9197764.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            22147..23457
                     /locus_tag="ACGI3L_002056"
     CDS             22147..23457
                     /locus_tag="ACGI3L_002056"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFG9197765.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            23483..24214
                     /gene="chbG"
                     /locus_tag="ACGI3L_002057"
     CDS             23483..24214
                     /gene="chbG"
                     /locus_tag="ACGI3L_002057"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HFG9197766.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLLSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            24227..24544
                     /locus_tag="ACGI3L_002058"
     CDS             24227..24544
                     /locus_tag="ACGI3L_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9197767.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(24656..25120)
                     /locus_tag="ACGI3L_002059"
     CDS             complement(24656..25120)
                     /locus_tag="ACGI3L_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197768.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            25390..26328
                     /locus_tag="ACGI3L_002060"
     CDS             25390..26328
                     /locus_tag="ACGI3L_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9197769.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLAKPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            26456..27469
                     /locus_tag="ACGI3L_002061"
     CDS             26456..27469
                     /locus_tag="ACGI3L_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFG9197770.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            27475..28497
                     /locus_tag="ACGI3L_002062"
     CDS             27475..28497
                     /locus_tag="ACGI3L_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFG9197771.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            28512..29294
                     /locus_tag="ACGI3L_002063"
     CDS             28512..29294
                     /locus_tag="ACGI3L_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197772.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            29306..30646
                     /locus_tag="ACGI3L_002064"
     CDS             29306..30646
                     /locus_tag="ACGI3L_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9197773.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(30741..33020)
                     /locus_tag="ACGI3L_002065"
     CDS             complement(30741..33020)
                     /locus_tag="ACGI3L_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9197774.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(33357..34520)
                     /locus_tag="ACGI3L_002066"
     CDS             complement(33357..34520)
                     /locus_tag="ACGI3L_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9197775.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VNYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            complement(34533..34808)
                     /locus_tag="ACGI3L_002067"
     CDS             complement(34533..34808)
                     /locus_tag="ACGI3L_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9197776.1"
                     /translation="MNAIIHANEKDNLVTCVRPLIKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            complement(34829..35803)
                     /locus_tag="ACGI3L_002068"
     CDS             complement(34829..35803)
                     /locus_tag="ACGI3L_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HFG9197777.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
BASE COUNT        13328 a         4496 c         6326 g        11890 t
ORIGIN      
        1 ttttataaaa attatattaa aaataaattt attttgctaa taaacatgtt attaacaaaa
       61 gaatagtact ataatgtata gatgataaaa actttaataa aaatttagtg tataggagtt
      121 gtttaagtat gatagatata agtattgatg acaaacttaa ggaaagatgg cctaatgcta
      181 agctgggttg cattcaagca aaagtagcag taaataaaag ctcagaaaaa ttaattaatg
      241 aaataaatga gttttgtgat actataaatc aaagtctaaa agttgaagac attacgaaac
      301 tagataaaat taaagatgca agaaatgctt ataaagagct tggaaaaaat ccaagtagat
      361 atagaacatc ttcagaagca ttggttagaa gaattattca agggaagggt ctttatacaa
      421 taaataatat agtagaaata aacaatttaa tatcaataaa atcattatat ccagtaggta
      481 catataatgt aagcaaatta cattcaccag tatgttttac tgtaggagat gaaggagaac
      541 agtataaggg tattgggaaa gaattaataa atatagaaaa tcttcctata ttatctgatt
      601 cagtgggtaa atttgggagt ccaactagtg attctgaaag agcaatgata acagaagatg
      661 caaatgaaat attaatttgt atattttctt ttagtcaaga atctgatatt gaagaatatt
      721 ttggatatgc taaggaatta cttaaagaat atgcagatgg aaaagatata gaaactaaaa
      781 taattaaata gaatctatat aacaacgtta tgttaagcta aaattcaata taaaaataag
      841 ttaagataaa gaaactaaca caaaattagt ttctttttta aaatagtagt ttagtgttac
      901 aaaaatagat agatagtccc acgattatta aaagtatggt aatatattaa tatagcagag
      961 attgtgttta agggattttg aaagggggga tttataataa tcattttatc taaaagataa
     1021 aatggtttta tagaaataac tatatattta aaaatataaa taatgataca gtaatttggg
     1081 tatataaaat aaggcataca tggttttgtt taaaaaccaa taaggtacat aggtaattac
     1141 aatgtaagga aggatttaat tatgattgat ggaaaagagg taaaacaaga aagtggacaa
     1201 aaaaatctaa aatttaagat agctatagta gtaggtgttt tgtttgtagc ttatatagga
     1261 atggcaatct tttttagaaa tcatttttac tttggaacga ctattaatgg cgtaaaggct
     1321 tcaggaaaaa cagttgagca agtaaatgat ttgttaacat ctagtactaa ttcctatact
     1381 ttaaacttag aggaaagaaa caataagaaa gaacaaataa aagcaaaaga tattgattta
     1441 aaatttacac cagatgataa agttcaaaag ataaaagata gtcagagcgc tattggatgg
     1501 attggtggaa tatttaagtc taaagagtat aataatatga taactctttc atataataaa
     1561 gatttactag aaaaaaggtt taatgcttta tcttgttttg atagtaaaaa tgttgtagaa
     1621 cctaagagtg cttatcctaa gtatgatagc actaaaaacg cttatgttat agtaccagag
     1681 gtacttggaa acaaagtgaa aaaagatgat ttttataagt tagtacaaaa ctcaattaat
     1741 tctgggaata cttctatttc tctggatgaa agtaaagttt atgaagcacc aaacaacaca
     1801 aaggattcag aaaagttgaa acaagctatt aagacattag ataagtatgt tggtgtagtc
     1861 gttacatatg attttagtga ccgtaaggaa actttagatg gttctgaaat taataaatgg
     1921 ttaaaagtag actcagaaaa gaattatgac ataacttttg ataatgatgc tatggtagaa
     1981 tatacaagag gtttaagtaa aaaatacagt acttttggtg actcaagacc atttaaaact
     2041 gccacaggta aagatattac aatttcaggt ggaatttatg gttggttgat agataaaaag
     2101 aaagaagctg aagcattagt tgatgttgta aaagctggta aaaatgttac aagagaacct
     2161 atttacatac aaaaagctgt atctcgtaat aaagatgata ttggaaatac atatgtagag
     2221 attagtcttt ctggccaaca tatgtggttc tttaaaaatg gagaaatgct tgtatcaaca
     2281 gacgttgtaa caggtgattt agctagagga tttgctacac catcaggtat atatcctctt
     2341 aattataagg ctagaaatgt ttcattaact ggtcaaggtt acagttcacc tgtaagttat
     2401 tggcttccgt ttaatgggaa cataggcatt catgatgcta cttggagaaa ttcttttggt
     2461 ggaagtatat ataagtcttc aggttcacat ggatgtgtaa atacaccttt ttctaaggca
     2521 aagaaaatat atgaaaatat agaaccaggt acaccaatta ttttatacta gtaaatgtgt
     2581 tgctaacagt taagcgaagt catcttagtt tatttaggat ggcttccttt ttatataaag
     2641 cttattgaag tttacagaaa gactacttaa aaggagaaat acataatgaa tgaaaaatta
     2701 actaaaattt tagaagaagc taagaatgat gatgaattta gaaaagaact tataaaaaca
     2761 agagaacaac gtgatgttat ggattcattt tgtaaggttg ttacatctag aggttatgat
     2821 atgacagtag gggaactttt ttctatggga gaagaatata catccaatct actgaaaagt
     2881 gtaaatggag gagcagcata tcctattgaa gattggagtg attggtacga ggattttttt
     2941 ataatgttgt cgaatatata gagtaactaa tgatattatc tacttaagat taatacattg
     3001 ccttaaaata aaactattag aactaggtgt aagttttatc aatctttaaa aatattgatt
     3061 tatttctaac tagatataaa aaaattagat taaaaataag gtgacaaaaa tcgatatagc
     3121 ttgatgattt ataaaagtta gataaaatag tgcgagatat ttctaaaaat tcaaaaaaaa
     3181 caataaactt caatggttag aggttgaaaa agaatataaa aaacttttat atgtaataaa
     3241 ttaaattaaa attataaaaa aaataaaata aaaatttaaa atgtcgacat aacgttaatt
     3301 ttaaaacaaa ataacgctat tgacaaacta tatcgcttta aattataatt attgaaaata
     3361 atggtattta aaaaccatac tcatgtcata gtctaaaagt aagtcaaaaa aggatgtaaa
     3421 tctaggcaag tactattcta aaatatgttt tattaagaaa taaacgttga aaaatattaa
     3481 ttattatata aaaatgctgt ttatacttta acaatgaggt agtaatctaa ttagaataaa
     3541 aaaatctaat tggttatata catagtaaaa aggtaagaga ggtgatttgg atggcttttg
     3601 aaataataaa aagcattgtt gaggcagagc agacagcaga cagtatcaaa gtaaaagctg
     3661 ttactgatgc agagtctatc agagctgatg ctgtaaacaa atgtgaaagc atatttgctg
     3721 atgtaaaaaa acaagcaaag cttatggaag aaactcttat tgagaaggca gtcaccgaca
     3781 gtagagcaga ggttgataaa atcttagcta atgctaaaag tgaatgtctg aaaattgaaa
     3841 aaactgctga agaaagaaaa agtaaggcta ttgaagcggt tattggaaag gtagtgagat
     3901 aatatggcaa tagttaatat gaacaaaata tctattgttg gcttagaagc tcaaaaaagc
     3961 cagattttaa agctacttat gaaccgtggg tttgttcaga ttgatgatag tgcctttctt
     4021 actgaggagg aggaattaaa aaattatctt gtaaaagata gtgaagaatc tgaagttata
     4081 atgctagagc agaaaatgtc tcatgtaaac caagcaatta atattgtttc ttcactagtg
     4141 aaacaaaaaa aatccctact tgcaccaaaa agagagttta acaaaattga tagtgaaaaa
     4201 gaagggcaag tttatgctga agctctggag ttaaacaatt tgcacaagga gataggtaca
     4261 ataaggtcta acataaactt acttaacaac aataaaagta tgttagaacc atgggtgaac
     4321 tttgatattc ctcttgaaaa tatggaaact aagtatacaa aaactatact tggaactgtg
     4381 cccataagcg caaacattga tgctttaaga gtaaaattag aagatgaaat accagaaagt
     4441 gttattggga ttgtcaattc tgacaagtta atgaactatg tttatttaat tactttaaaa
     4501 gaaacttttg atgatgtttt agaagtttta aaagaattta atttttcagt ggtttcatta
     4561 ccaaatgaag aaggtacacc gttacaagct atcaagaaat acaatgaaat gataattaga
     4621 caggaaaacg tttctaagga caaaacagag gaaattaaaa gacatgcaga tagtatacac
     4681 atgcttgaaa acctatatga tttttacact atagaaagag accaaaaaaa gattatagag
     4741 agacttgtca aaacaaaaac aacattctgt cttaatggtt ggttaccaag caaaagggca
     4801 gatgaattaa ttaaagaaat tacagaaaag tttaattgtt gtgttcagac tgaagaagga
     4861 agtaaagaag aaggcttccc aattctgctt gaaaacaata aattagtaac accttttgaa
     4921 agtgtaacta acatgtacag ctatccaagt acaaaagata ttgacccaaa tacaatttta
     4981 actttcttct ttgttgtatt ctttggaatg atgctaagtg acgccgcata tgggttaata
     5041 attgcagtag tctgtggatt tgttgtatat aaattaaaga tacaaaaagg tgaaggaaat
     5101 ttaattaaac ttattggtat ctgtggagtt tcaactactg tatggggtct tatattcggg
     5161 ggtattttgg gggatttaat tcctataaaa gcattaatta atcctttaga ggatgttatg
     5221 acacttatgg gaatgtcgtt actgttcggt attatccata tatatgtagg tttgggaata
     5281 aaagcatata cattaataag aagtggaaag gtaatagatg caatctttga cataggtttt
     5341 tggtatttgt gtataacagg tgtatgtcta cttataatac cttttgttgc aggggatata
     5401 ggtgtatttt cagaagtagg aaaatattta gcaattatag gtgctatagg tcttgtactt
     5461 actcaaggaa gaagctttaa aggtattcct gttaagcttt ttaaaggatt ttcaagtctc
     5521 tatggtataa caagttattt tgctgatata ttatcttata caagaattat ggcgctttgt
     5581 ttaacaacag gagttatagc acaagttatc aaccttttag gagctatagc tggtccgata
     5641 cttgcagttg taattggtgt tgtaggacac acaataaacc ttcttataaa tgcactaggt
     5701 gcatatgttc atacaagtag gttacagtat gtagaatttt tcaataagtt ttatgaaggc
     5761 ggaggagttc cttttgttcc gtttaagtat aaaacaaaat atacaagcat taataaaaag
     5821 gagatgtaaa tatggaattt ttaaacgcgt taggaaatgg tcaatttttg gcaatatcag
     5881 gagctgctat agcagcatta tttgcaggta tgggttctgc taaaggtact tcaatagcag
     5941 gtcaagccgc agcaggtgtt gtaacagaag accctagtaa attcggtcaa cttctagttt
     6001 tacaacttct tcctggtaca caaggtctgt atggatttat catagctttc cttattttat
     6061 caaaagcagg aattattggt ggagatgcaa taccaacatc agctcaaggt ttacaacttc
     6121 ttatggcagg acttccaatt ggtttagttg gtttagtatc aggtatagca caaggtaaag
     6181 cagcagcagc aggagttgga atagttgcaa aaagacctga agaacttggt aaagctataa
     6241 catttgcagc aatagttgaa acatatgctc ttttaggact acttgtttct ttcttagctt
     6301 acaatggaat tgcaattggt taattataaa ttataattca taagtaaaaa aaatgaaaag
     6361 gaggaagcac tcctatgggt aatgaacaaa aaatgattga cagaattata gctgatgcca
     6421 aacaagaagc acaagaaata ttggataaag ctaaaagtga agcagattta aaagtaaatt
     6481 cagctaatga aaaagctgaa aaggaaatgg cttcctatac aaagcttgca gaggcagaag
     6541 cagaaaaagc ggcttctaag gaaatatcag gagcttatat ggaggctaaa aagcaaatat
     6601 tatcaaaaaa acaagagatt ttagaagagg taattttaga agctaaaaac aaacttttaa
     6661 atcttaaaga taatgaatat gaagagatta tactaaacat gattgaaaaa tcaaattgta
     6721 cagatgattc agagatagta ttatctaaaa aagataaaaa aacattaaaa gatgtgctat
     6781 caaaaaaagg cattaaagtg tctgatgaaa ctagagatat tactggaggt ttcatagtta
     6841 aaaaaggtga cattgagtac aattattcat ttgaagccat aattgcagta gagcatgaat
     6901 atattgaaca aattgcagca gaaattttgt ttaattaagg aggggttaaa aaatggcaga
     6961 agaaaaaact tatccctatg ccgttgcacg aataagagtg cttgaaaaac agcttcttaa
     7021 cagacaaatg tttattcaaa tggcagaagc caaaagccct gaagactctt taagaattat
     7081 agctgaggca ggttatgctg atacatcaaa taataatata cataattttg agaatatttt
     7141 gactcaagaa ttatcaaaga catatgaaat tcttaaaagt ctagctcctg aagaaaaatt
     7201 tgttgatgta tttctttata aaaatgacta tcacaattta aaagtgctga ttaaagaaga
     7261 aatttctggt gtagatggtg agaaatattt aattgatgga ggtacaattc ctcttattaa
     7321 gcttagagaa tctttagcaa atcgtagttt tagtgattta cctaagataa tgtcatcagc
     7381 tatattagag gcatttgatg tttataataa gacacaaaat ggccagatgg ttgatattgt
     7441 tctagataaa gcaaccttta ccagtatgaa agaaactgct aaagaaagcc aaaacaaatt
     7501 tgtaatagat tatgttatga aagtttgtga tttaacaaat ctaaagagtt ttataagagt
     7561 caaaaatatg aagaaagatt ttgatatgtt tatgaatgtg tttgtttcag gtggctcact
     7621 tgataaggaa aaattcttag aagctttttc ctcagatact ccagcatcat gttttaaatc
     7681 tacttcttac tctgatgtct gtaaaaatgg catggatagt ggttttactg tctttgaaaa
     7741 actttgtgat gactatctta tggaatatgt tagaggagca aaatttaagc ctcttacatt
     7801 agaaccacta attgcatatt tatatgctaa agaatcagag ataaaaacaa ttagaattat
     7861 tttgactagt aagcttaata atatagacgc agatactata aaagaaaggc taagggatgc
     7921 ttatgtataa ggtaggagta gttggagata aagatagcat catgggattt ttagctcttg
     7981 gaatagatat cttcccagcc tatgatagtg acgaaattaa aaaaagtata cataagttgg
     8041 ttgaagatga atatgcgata atttatatta cagaacaggc atcattgctt gcaaaagaat
     8101 caatagcaaa atacaaagat taccaacttc ctgccattat agttattcca ggtattggag
     8161 gaagtatggg attaggtatg aatgaagtaa gagaatctag taaacgtgct ataggtgcag
     8221 atatattatt taaagaatag atgaaagttg aataaaagac aatctcaaat tttattggtg
     8281 ctaaatatat gtgctaataa aatataggag ggaatattta aattttgata aagtatatga
     8341 ttgcaggtga gagaatatga aaacaggcac aattgtaaag gtgtcaggac cgcttgttgt
     8401 agcggagggc atgagagatg cgaatatgtt tgacgtcgta agagtttcag ataaacatct
     8461 tataggcgag attatagaaa tgcatggaga taaagcttct atacaggttt atgaggaaac
     8521 ttccggtcta ggaccagggg aagaagtagt ttctcttgga atgcctatga gtgttgaact
     8581 tggaccaggt cttatttcaa ctatttatga tggtattcaa cgtccacttg aaaaaatgta
     8641 tgatatttca ggtactaata taactaaagg tgttgaagta tcttcacttg atagaacaac
     8701 taagtgggaa tttaaaccta aaaaatctgt tggtgataag gttgtagcag gagatataat
     8761 tggtggcgtt caagaaacag cagtagtaga atgtaaaatt atggttcctt atggagttaa
     8821 gggtactata aaagaaatat attctggtga atttactgtt gaagatacag tttgtgttat
     8881 tacagatgaa aaaggtaatg atatacctgt aactatgatg caaaaatggc cagttagaaa
     8941 agaaagacca tatagagaaa agaaaacacc agattcactt cttgttacag gtcaaagagt
     9001 tatagataca tttttcccaa tcacaaaagg tggggtagca gctataccgg gaccttttgg
     9061 aagtggaaaa actgttacac agcatcagct tgctaaatgg gcagatgcag atatagttgt
     9121 atatataggc tgtggcgagc gtggaaatga aatgacagat gttcttcttg aatttcctga
     9181 attaaaagac ccaagaacag gcgagtcact tatgcaaaga actgtgctta tagcaaatac
     9241 atcagatatg ccggttgctg cacgtgaagc ttctatatac actggtatta caatagctga
     9301 atattttaga gatatgggat atagtgttgc acttatggca gactctacat caagatgggc
     9361 tgaggctctt agagagatga gtggtcgttt agaggagatg cctggtgaag aaggttatcc
     9421 tgcatactta ggttcacgtc ttgctcaatt ctatgagaga gcaggaaagg taaattgtct
     9481 aggtatggat gaaagagaag gaacacttac agcaattggt gcagtttctc ctcctggtgg
     9541 tgatacatca gaacctgtca gccaagcaac tcttcgtata gtaaaagtat tctggggtct
     9601 tgatgcatct ttagcatata aacgtcattt cccagcaatt aactggttga ctagttattc
     9661 actctatcag gaaaaagttg atgtatgggc agataaaaat gtaaatgata atttctcagc
     9721 tcaaagagct caagctatga aacttttaca agttgaatct gaacttcaag aaatagttca
     9781 attggttggg gttgattcac tttcagatgg agatagattg atactagagg ttactcgttc
     9841 tataagagaa gacttccttc atcaaaactc tttccatgaa gttgatactt atacatcact
     9901 tcataaacaa tatagaatga tgggacttat attaaaattc tataagtcag cacaagatgc
     9961 tatcaagcaa aatgttacta taaacgatat tatcaagctt tcagttcttg aaaagattgg
    10021 tcgtgctaag tatgtagaag aaggcgatat agatgcagct tacgattcaa ttgaagatga
    10081 aatagataac gagcttgcag accttattaa aaagaggggg gctgaagaac tatgataaag
    10141 gaatataagt caatacaaga ggtagccggt cctcttatgt taataaacgg cgtagaaggt
    10201 gtaaaatttg atgaacttgg agaaattgaa ctttcaaatg gagaaattcg ccgttgcaaa
    10261 gttctagagg taaatggaga tactgcactt gttcagcttt tcgaaagctc aacaggtata
    10321 aaccttgctg aaagtaaagt tcgtttttta ggaaagagtc ttgactttgg agtttcacca
    10381 gatatattag gtcgtgtttt tagtggaatg ggtagaccta ttgatggagg tccagaaatt
    10441 ataccagata aaagacttga tataaatgga gctccaataa atccagcagc acgtgattat
    10501 ccggccgagt ttatacaaac tggagtctct gctatagatg gacttaatac attggttaga
    10561 gggcaaaaac ttcctatatt ctcagggtct ggtttgccac atgccaatct tgcagttcag
    10621 attgcaagac aggcaaaagt acgtggaact gattctaagt tcgccgttgt atttgctgca
    10681 gttggtataa cttttgaaga tgctgaattt tttataagcg attttaaagc aactggtgca
    10741 atcgaccgtt ctgtagtgtt tgtaaacctt gcaaatgacc cagctgtaga gcgtgtatct
    10801 acacctagaa tggcacttac agcagcagaa taccttgctt tcgagcaaga tatgcatgta
    10861 cttgttataa taacggatat tacaaactat gcagaggcgt tgcgtgaagt ttcagcagct
    10921 aaaaaagaag ttccaggacg tcgtggatat ccaggatatc tttatactga ccttgctact
    10981 atgtatgaaa gagcaggaaa aatgaaaggg catgaagggt ctataactat gattccaata
    11041 cttacaatgc ctgaggatga taagacacat ccaattcctg accttacagg atacattaca
    11101 gaagggcaaa ttatacttag ccgtgaactt tataaaaaag atatacagcc tcctatagat
    11161 gttttaccat cactttctcg tctaaaagat aaaggtattg gtaaaggtaa gactcgtgaa
    11221 gaccatgcag atacaatgaa ccagcttttt gcagcttatt caagaggtaa ggatgcaaaa
    11281 gaacttatgg ctatacttgg tgaatctgca ctttctgaga ttgatttaat gtatgctaag
    11341 tttgcagatg aatttgagaa agaatatgtt tcacaaggat ttagaactga tagaactatt
    11401 gagcagacat tagaaatcgg atggaagctt cttagtatgt taccaaaaag tgaacttaaa
    11461 cgtatccgtg atgaatattt tgaaaaatat atgcctaagg agtgatatct gtggctagat
    11521 taaatataaa tccaacacgt atggaaatga ctagacttaa gaaactcctt aaaactgcta
    11581 caagaggtca taagcttctt aaagataaac ttgatgaact tatgaaacaa tttcttgaga
    11641 ttgtaagaga aaataagcga ttgcgtgaag aagcagaaaa tgctcttgat actgcttata
    11701 aaaactttat aatcgcaaga gcagttatga gtcaggagta tctgggttca gcacttatga
    11761 tgccaaagca atcagtttca gtagatgttt ctacgagaaa tataatgagt gttgatgttc
    11821 ctgtgtttga ctttaaaact gaaaacaatc aaagtgatat ttatccttat ggtcttgctt
    11881 ttacatcagg tgaattagat tctgctatgg aagctttctc agatgctatg caaccacttt
    11941 taagacttgc agaaagtgaa aaaagtgcac agcttcttgc acaagagata gaaaagacac
    12001 gtagacgtgt taatgctctt gaaaatgtaa tgataccaaa ttacattgag actattaagt
    12061 atatagctat gaagcttgaa gaaaatgaga gagcaagtac tactagactt atgaaggtta
    12121 aggatatggt gcttaaaaaa gcacttgaag aaaagaaaaa aaatgatttg gttgtataat
    12181 taaatactta taaaaataag tctaacattc tactttatag aggttagact tattttttat
    12241 gtttaaatta aaatgtagat actataaaaa ttaatatatt gtttaaaaac agactgtatt
    12301 taactaaaaa taatatattt aacaaaaatt tctaaaaatt aacgaactgt taatttacac
    12361 ttaactttat attaacaaat taggtgtatt atataaacat aagcaaaaac aataaaaaac
    12421 aaataaaaaa aggaaaaaac acaaaggggg aagatatgaa agaatttata tttacttgtc
    12481 tgtgcattgt agtgattaca tttatgacaa gttgcatatc aacaacacca caaactactc
    12541 aaggaaaagg aaataataaa cttacaatat atgcagcact agaggaagag cagatagctt
    12601 attatatgga aggttttaga gaagagtatc ccaatataga tgtagagata gttatggatt
    12661 ctcatggtgt aatagcttca aaactattag cagaaaaaga taatccacaa gcagatatta
    12721 tatggggatt atcagcaatg aacatgatag agctaaaaaa agatggtgca cttgaagcat
    12781 ataagcctaa aaattatgat aaagttgata aaaaatttaa agatactgaa gatgatgtat
    12841 cttgggtagg aatgagtgtc ccagagacag caatagtagt taattataag gaacttaaga
    12901 aactaggtat agatattcca aaaagttatg aagatttaat aaaaccagaa tataaaggac
    12961 ttataacaat gccaaatcca gcatcatctg gaacggggta tcttacagta tcagggctta
    13021 ttcaaatgat gggtgaaaaa gatgcttaca attacatgga taaattacat aaaaatatag
    13081 ccacatatac acactcgggt tcaaaacctg cgaagttagc tggctctgga gagtatccaa
    13141 taggtattac acttggatat agagctacac aacaattatc tagtggagaa cctatagagg
    13201 ttgtatttcc aaaggaaggt tcaggctggg acttagaagc aaatgcctta gttaaaaaag
    13261 ataatataaa aaaagaagca aagctatttt tagattgggc aataagtgat tcagctatgg
    13321 atagatatgc acatgaagta gcagttactt ccataaagac agataatcca gttccaaaag
    13381 gttattctaa acaaccattt gaacagctta taaaagaagt tgatttaaac tctgctgcca
    13441 aaaacagaag tacagtactt aaaacttggg aatcaaaata cggttcaaaa tctgaaagta
    13501 agtaaagttt aaattaataa tttagatgaa agaattttag aagaaaaagt aggatataaa
    13561 atttaaaata aaaaaataac tatataagga gagataagat atgagttact taaaaataaa
    13621 taatgtgttt aaaagttatg accaaaaaag ggttttaaat aatattagtt tggatattga
    13681 agaaggagaa tttctatgtt tactcggacc tagtggatgt ggtaaaacta cattacttag
    13741 aataatagca ggtcttgaag atgtaaatag cggaactata attctccagg ataaagatat
    13801 tacaaattta gagccatcaa agagaggttt tggtatagta tttcaatcat atgcattatt
    13861 tccgaatatg actgcttata acaatatagc ttttccacta aaagagagaa aagtttcaaa
    13921 aggaaaaata gataataaag ttaaggaagt acttgaaaca gttggattga ctaatgaagc
    13981 tcataaatat cctaaagcat tatcaggtgg gcaacaacag aggattgcaa tagcaagagc
    14041 attagctctt gaaccaaagt ttttactttt agatgaacca atgtccgcat tagatgcaaa
    14101 ggttagacac aagcttagaa tggacattaa aagattacaa aaagaactta atataacgac
    14161 aataatggta acacatgacc aagaagaagc tataactatg gcagataaaa tagctattct
    14221 aaatggagga gatataatgc aaatagggac tccagaagaa atataccaaa atcctcaaaa
    14281 cctatttaca gctcaattta taggagatac aaactgtttt gataatggag attctatatt
    14341 aactgtaaga ccagaatatg ttcaaataga gaaatcgaca aaagaaaact accaaggaat
    14401 aatatcaaat atagagttta gagggaattt attgagagtt gaaataaaag ataaattaaa
    14461 tgaaaatttc ataataagtg atgcttctat aaaagagtgg gttaatttaa atttagtaga
    14521 aggtgacctt gtaaaaataa gtatagacga aaaatactat ttaaagtatc caaaagttaa
    14581 aggagcataa gtgtatgaat aataatgcta taagttctaa aagtataagt cttaaatcaa
    14641 aaatgaattt agatataaaa aaatgtatgc ttacagtatt agttatgtct ttagtaatat
    14701 ttttattagc acctataata tatctatttg tacaggcttt tttagataaa gatggagtct
    14761 ttgtaggatt acaaaacttt caagaatact tggcttctga atctctatta aattctctaa
    14821 aaaatacagt atttgtatca gttatatcaa ctgtaatatc actaacactt gcattagtat
    14881 atgcatatgc attaactaga acaaagatta aatttaaagg tttttttaaa tcattagcta
    14941 tgtttcctat gtttgctcca acaatgatgc atgcaatagg tctagtatat ttatttggaa
    15001 atcaaggttt ggtaactaat ttacttggag tgcatgttcc aatatatgga gcagtgggaa
    15061 taatattggc acaaattata tatgtatttc ctcaatcatt tcaaatactt tatatatctc
    15121 taagttcaac cgattataga ctatatgaag ctagtaatac tatggggata agcaagataa
    15181 gagaatttat aagcataaca ataccaagta taaaatactc tttaataagt tctgcattcg
    15241 tatcgtttac attatgtttt acagattttg gagctccaaa ggtgatagga ggagagttta
    15301 atgtattatc aatagatgta tataagcaaa ttatagggca acagaatatg ccaatgggag
    15361 caactgtatc aatattactt ttaatacctg caataatatc gtttatagta actaaaaaaa
    15421 ttgaaaaaaa tcaaaattca tatataactt caaagtcaat tccatataag gttaaaacta
    15481 ataagttaag agatagtatt ttaggagggg ttgtaggaat tattgcattt ggtataatag
    15541 ctgtaatgtt aactgtaatc ttatcttcat taatatcagt ttggccatat gatttaagac
    15601 tgacactgga acatttttct atgaaaaaca gtattgatgg gattaaacca tttataaatt
    15661 caataaaaat gtcactattg acagctattc tagggacgag ctttgttttc ttatttgcat
    15721 atttgaatga aaaaacagaa aaagctccat atttaaaatc atttgggtat tttttaagta
    15781 cattgcctat ggcattgcca ggattagttt taggtatagc ttatgtatta ttttttaata
    15841 aattagagtt taattttatg gatacaatat acattaagaa tttgtttaat ggattatatg
    15901 gaacattact tataatggtt atatgtaata tagttcattt cttttcagta gcatttataa
    15961 cagctactac tgctattaag aaagtagata aagaattgga tatggtagct aaatcaatgg
    16021 gaataaacag cgcatcaatt cttaagaacg taactatacc actttgtttg ccagcagttt
    16081 tagagaactt tatgtacttt ttcctaaact ccatggtgac aatatcagca ttagttttta
    16141 tatatactgc aagttcaaaa gtagctgcaa tatcaattgt acaactagat gataagggga
    16201 gtactgcaca ggcagcatca ctagctgtgt taatattagt cacaaatata ttagtgaaag
    16261 taatatatga atttataaag aatcgtttag aaaaaagaac aaactttaat taaataattt
    16321 atcttataaa aacacaaatt taaaaaagtc tattcttgtg atttattatt taaagaatag
    16381 actttttaaa tttattattg atattgttta ttaattttcc ttttgttatc atacatttga
    16441 gaatctgcac gacgatatgt atcaaataaa gaaacatcta ctttttcatc aaaaatagca
    16501 tatccaatag acattgataa ttttaattca ttagttgagt tttcttcaac tatttttaaa
    16561 ttaatattat ttataatatt atttatttct ttgtgagata aattttttag aataattatg
    16621 tattcatcac ctccaatacg ataaactata tattttttat ttattacata ttgtataatt
    16681 ttacttgctt gcttaatata taagtctcct gtctgatggc caaatttatc attaatcttt
    16741 tttaaaccgt ctaaatctat tgatatgata gatattagat tctttagatt tgaattgttt
    16801 aagttattca tatctatttc aaaagcattt ctatttttta ggcctgttaa ataatctgta
    16861 ttagcaaaat cagtatatgt aggattagat attcttttaa atagaatcac tgcaatcaat
    16921 gctgatatta gacaagttaa taatgctatt attggtgtaa ctatacttat aaatttaaat
    16981 gtattgtatt gatgttttgc ttcaaattca attcctatta ctccaacaac cttaccaaca
    17041 tcattgtgaa taggaaaata cgatataaat atgtatcccc aagatgttga tttaatcttt
    17101 ttaggtaaca atatatgatt atctaatgct ttgttaaggt ctccccaaat ctctttttct
    17161 atcaaatcac cagcatttct aaaatcactc ctagatgaat ttaaaccatc aacaacatat
    17221 actagtgatc catcttttgt ttttttagca gtatatagat acatgactcc agtagtattt
    17281 tttacagatt ctaaaaggat tttagaactt ttataagact tttttgattg gtcttcttta
    17341 gaattaattt cagtaaaggt atttttatca atatttcttt ctacatattc atagatatgt
    17401 tttgacctct cacttaaaga gtatatcatg ctcttataag ttagtgtata attaaaaaaa
    17461 tatacacatg aggaagatat tattacaata attgcagtaa gtattgaaac ctgcatatca
    17521 actctattga attttttatt tattttcata gcttaaatgt cttgtgaaaa gaacctccca
    17581 caatctcccc ataattaata tatatctata aatttcacca taatatattc atatattatc
    17641 aaatttgtgt ggaaattaca attagtaaac atgcttaaag cattcaaata tagttttttt
    17701 attattatag tatactattt tatgtataaa taaaattata tataaatcat tgatattggt
    17761 tgtttattaa tggaagatac cgtataaaat attctaattg gttacgatat gtatacttaa
    17821 ttgaagttaa gttaaaggtt agaatatgta ttgatgaaat ggctagattt atattcataa
    17881 gtattaattt tatcatagat aggtaaaata ctgtatctta aacataagta tgattgagat
    17941 gcaatcctga gatatgataa tataaattga aggatagtga actcaatcaa ataaaatgat
    18001 taatctagct atataagcaa ataaatttaa tataaaagag gtggaaaatg aaagacagac
    18061 ttaatttaac agaaggaaga attacagaaa aattacttaa gctatcactt ccaataatgg
    18121 ggacttcatt tatacagatg gggtataaca tgatagatat gatatgggtt ggtaaagccg
    18181 gaagtaaagc agtagctgca gttggaacag ctggtttttt tccatggctt gcaatggcat
    18241 ttattatgat ttcaaaagta ggtggagaga taaaagtagc acaaagtatt ggtgcaaata
    18301 atataagcac tactaaatca tatatgaagt cagcaataga aataaatatt atactagcaa
    18361 taatatatac aatttcttta atagtactta ataaacaatt gataggtttt tttagattag
    18421 gagacttaga agttataacc atgtctagac agtatttgat aatagtagct ctaggtatgg
    18481 tattttattt tattaatcca gtatttactg caattttcaa tggtcttgga aatagtaaaa
    18541 ctccttttcg tattaataca gtaggattaa taactaatat tatacttgac cctatattaa
    18601 tttttggatg gggatttgct ccaaaacttg gtgttgcagg agctgctatt gcaactgtat
    18661 ttgctcagat agtagttact acatgtttta tatatataat agttaaaagt aaagaagaat
    18721 attttaaatt aagactattt aaagaaatag agactaaata ttataaagtt ctgtataaat
    18781 tgggattacc tatagcaata caaagtggta tgtttacagt attctcaatg ctattaggag
    18841 taatagtagc atcatggggg cctgtggctg ttgcagtaca aaaagtaggc tcacaaatag
    18901 aagcaatttc ctggatgacg gctgaagggc tatcagttgc attaggcagt tttgttggac
    18961 aaaattatgg tgccaagaag tattctagaa taaataaagg ttgcaaaata gctataactg
    19021 tatcttctgt acttggtata ataactactt tagtattagt gtttgcagga gagagtatat
    19081 tttctatttt tatagatgaa agtgaggcaa tagaaaaagg agcagtttat cttaaaatat
    19141 taggctattc tcaatttttt atgtgtttag aaataataac aacaggagct ttcaaaggat
    19201 tagggagaac ctatatacct tctattataa ttactatact gactggtgca agagtaccat
    19261 tggcttactt tatatctaga ccagaaatgt tgggtctaaa tggtgtatgg tggagtataa
    19321 ccttatcaag tatattaaaa ggtatattaa tgataagtct atttatatct ttattaaaac
    19381 tcggaaagtt gtacaagatt tctgaataaa atttaaatta tcttaaatgt atagacattt
    19441 tctttgtttg tatataaaat tatcttatta tataaaagat ttaataagga gtgaattaaa
    19501 tgaaagagcc aatttataaa gttatagaaa atcatgttag agagttaata aattcagaca
    19561 gtttgaaaga aggggattta atcccttctg aaaaacagct gagtgaagaa tttaatgtaa
    19621 ctagaatgac tgtaaggtct gcacttaata atctagttaa agaaggctat ataactagac
    19681 aaagaggtgt aggtagtata gttattgcaa ataatatata tgataatata tcgtctgtaa
    19741 gtggatttac taaagagatg gaaagtaaag gctataaagt atctaatata ttggtatctc
    19801 ttgaaatagt tcaggcagat gaaaatttat caagtaagtt gaatataagt ttagaagaaa
    19861 atgtttggga aataaaaaga gtaagattag ctaatgatgt aagagtttca tatatgatta
    19921 cttatatgcc agttaagtta tttccaaatt taaataagac tcattgtgaa aattctcttt
    19981 ataattttgt tgaagaagtg tgtggataca agatagccat gtcagagaga gaagtacaag
    20041 ctgtaatatc gaatgaagag tgtatggata atctaaaatt agaagaacca gagccacttt
    20101 tatatataag ccaaatttgt aagttacaaa atagtgagat ttttgagtac tcacacacat
    20161 atcactatgg atatacatta actttgaatg ctgttgtcga ataaaattta aataaaatga
    20221 aaaagttttc ttgaaatgta tatacatttg gtatataata atatcaagaa ttaaatgtat
    20281 atacatttaa aaataagata tatacattaa gaaaaaatta atagaaaaac atattttaaa
    20341 tgtatagttt aaaaaactta tgacttaaaa aatatttaat gaatctaatt tggaggggaa
    20401 aaaatgataa aaataatgtt agcttgttca gcaggaatgt caactagttt attagttaca
    20461 aaaatggagg atgcagcaaa ggaaaacggt atagaagcaa aaatatgggc tatatcagaa
    20521 gtgaacttaa aaaatgaaat agaaaattgt gatgtcttac ttttagggcc tcaagttaga
    20581 tatgtattag gaaaagcaac tgaaatggca aaaccatata atattccagt agaagttata
    20641 aatatgatgg attatggaag atgtaatgga aaagctgtgt tagatagagc tgtagagtta
    20701 aatagttcaa aataaagttg tactggagga tgtaaaatgg aaaaattcat gtcatttatg
    20761 gataaatata tagtgcctgt agctgctaaa ataggagctc aaaggcactt agtagcagta
    20821 agagatgcat ttatagtaat gatacctata actatggtag gtgcattggg aacattgata
    20881 aataacttac cattggaagc atacaaaaat ttgatggcaa gtatatttgg agaaaactgg
    20941 accacatttg gaggcgacct ttggtgggga gcaataggta caatggcagt attcttagta
    21001 ataggtgttg cttattttct agcaaaatct tatgagagtg atgggttaca atctgggctt
    21061 atagctttat ctatcttttt tataatggct ccacaaattg gtaaaatagt tcctgaggga
    21121 ggaactacag tagttgaagg atggggaatg atacaacaaa cctacttagg tacagcagct
    21181 ttattctctt ctatattaat aggattatta tcaactgaga tatttgtaag attatctaag
    21241 gtaaagaaat taactataaa aatgccagat ggagttccac cagcagtttc aagatcattt
    21301 gcaaagttaa taccaggaat gttaactata atgatattta ctgtaatagg aatatttata
    21361 aaaatgcttt ctaatggaag tttcttaaca gatattttaa atacttattt aggagcacca
    21421 ctatcaaatg tagctgatag tctaggttct acaatgctta ttgcatttat aattcatata
    21481 ctttggactg ttggacttca tggtgcaaat atagcacttc cttttacaga aactatactt
    21541 atgaaattag gtggagaaaa tgctgccttg gctcaagcag gagcaacgga aggataccat
    21601 gtacttgcag gtgcattctt tgatgcattt gtatatttag gtggttctgg aatggtattg
    21661 ggattaatag tagctttatt aatagctgga agaagacgta aagagatgat agtattaggt
    21721 ggtccacctg caatatttaa cataggagaa ccattgatat ttggacttcc aatagtttta
    21781 aatcctatat ttatgattcc atttgtactt gcaccagtaa tatgtagtgc tgtatcatac
    21841 ttagcaatag attttggatt agtagcacca gtaattttac ctaaaatacc ttgggtaaca
    21901 cctcctatat taggtggagc aatggctaca ggtgactgga ctggtggagc tttagcacta
    21961 tttaatttaa tattatcaat attaatatat attccatttg tcatagcgtc tgaaaaaatg
    22021 gaagctaata aattgaaaat taacaactag gtagttttat ttcggtaaat aaatgtatag
    22081 agttttaaat aaatgtatgg ggttttgtag agtatattaa attataggta aggatggtat
    22141 aatgagatga aaaagggact aaaaatagtt acaattggag gaggttcaag ttatactcct
    22201 gagcttgtag agggttttat aaatagatat gaagagttac ctgtaaagga attatggctt
    22261 gtagatatag aagctggaaa agaaaaatta gagatagttg gaaatctagc taagaggatg
    22321 gtaaaaaaag ctggagtaga tatgaaaata aatcttactt tagatagaag agaagctcta
    22381 agagatgcag actttgtgac aacacaactt agagtaggtc ttttagatgc gagaataaaa
    22441 gatgaaacta ttcctttatc tcatggagtt atggggcagg aaactaatgg tgctggaggt
    22501 ttatttaaag cccttcgcac aataccagtt atatttgata taataaaaga tgtggaagaa
    22561 ttatgtccaa atgcatggat ggtgaatttt acaaatccaa caggaataat aacagaggct
    22621 gtattcaaat atactaattt tagaagatat ataggtctat gcaacgtgcc aattcattta
    22681 aaaaatgatg ttgccaaact atttaatgta gaaagtgaca gaataagtat ggattttgca
    22741 ggtcttaatc atatggttta tggtctaaat gtatctttag atggagaaga tgttacaaaa
    22801 gaagcaattg ataaatttgt caaagcagat ataagtatgc aaaatataaa ggcaattgat
    22861 tttaatgctg aatttgtaaa atctttgggt gcaatacctt gtccatatca tagatactac
    22921 tataaaacta aagaaatgct tgaggatgag ttgagagagt ttaaagaggg aaaagctaga
    22981 ggtcaagtag ttaaagaatt ggaagaacaa ttatttgaat tatataagga tgaaaaatta
    23041 gatgtaaaac cacctcaact tgaaaaaaga ggaggggctt actatagtga tgctgcttgt
    23101 aatttaataa gttctatata caacgacaaa aaagatatcc aagtagttaa tacattaaat
    23161 aagggttcta taagagattt taaagatgaa caagcggtag aagtaagtag tgtaataaca
    23221 aaaaatggtc caaaaccaat aagtatagga tatttaccag attctgtgca tggattagta
    23281 agtcaaatca aatcatttga agtattggca gctaaagcag ctgtatatgg cgattatgaa
    23341 tctgctcttt tggcactttg tataaaccca ttgattccat ctgatgactt agcaaaaact
    23401 atattagacg aaatgttgga agctcataaa gattatcttc ctagatttaa tagatagttg
    23461 tctatagaaa gtaggttatg gtatgactaa aattataata aatgcagatg attttggata
    23521 ttgtgaagct gtgaactatg gaataatttc agctcataat aatggtatag ttaggtctac
    23581 ttctatgatg gcaaatatgc ctggggtaga acatggagta ggcttactta aagaaaataa
    23641 aactttaaat tgtggagttc atatgacttt aagttgtggt agaccattat tatctaactt
    23701 aaaaactatt gttgataaag acggtttttt tattaggagg attacagacg aaattattga
    23761 aaaaatggat tgtgatgaga tttatagaga actttgtgct caaatagata gggtaaaagg
    23821 gcttggaata gatatatctc atttagatag tcaccatcat atccatactt tattaagttt
    23881 aaagccagta atagagaaga ttgtaaccaa gtataatctt ccaataagag gtggatttga
    23941 atataattta gagtattcta aagtagttcc tttaatagat agtttttata aggaaaatgt
    24001 aagtgaagaa tattttataa aaaatataga cgaaataatg aagtatgatg tagtggatat
    24061 tatgtctcac ccagcttttt tagatgatta tattttaaat tctacatctt atgctattga
    24121 tagaacgaaa gagcacaaga tacttacatc taaaaaagtc aaagaatttt tagaaaagaa
    24181 tggattagtc atatcaagct atagagatat ttaggaggtc gaataaatgg atgagaagat
    24241 gatagagata tcttttggaa taattggatt tgcaggtgat gcgaaagggc tagcatttga
    24301 agcaataaaa gaagcaaaga gcgggaatat agataaagct agagaatgta ttgaaaagtc
    24361 gaaagaatca attcataaag ctcataaatt ccaaacagaa ttgatacaaa atgaagctaa
    24421 tggtaataaa actgaaataa gtgttatact tattcatgca caagaccatt taatgacagc
    24481 tatgaatttt caacaattag cagaagaatt tatagatgta tatgaaagat tagaaagtaa
    24541 gtaatttaaa attattatta aaaaagagtg tataaaaata atttttataa ttattaaatg
    24601 cactcttttt ttatttaagt agagtttagc aatatagtat tatgttattg atactttaaa
    24661 atttagactt ctcataattg taaggtatac tagtaccaac aactacatct tcaatttttt
    24721 caacaataag ccaatcatcc atatttcctt gatggtcaaa atcaagaggt gttatttctt
    24781 caacattttc aaattcaact aagcataaac attttttatg ccaacgaact ttttgctttt
    24841 cagataaatt taattttggt tgattttcat ttaaaatttt agaaatttca tcttctgtta
    24901 atttaacata gttttctacc tttttaacag tggcttttgc agatattttt gcagttcctt
    24961 tttccataaa ataaagtaac tcatcttcaa atactctact atgtggtatt tttctaccag
    25021 cagcacctct aataaccatt gtttttgttc cagccaagat tttatctaag accttttctc
    25081 ctttttttcc tgcattatca caatatacta aatgtaccat gttttgaatc ctccttacta
    25141 aattcattat ctataaattg cattttatca ttgtttaact gaaaagtcat tgtatttgtg
    25201 tccaattctt taaaaaaata ctgtttaata taagaaaacc ttatctaagc tatatataat
    25261 taagattaat taggaatttt tatcctttta caaaataata ttgactaaaa atagaaaaat
    25321 gctataataa atatgtgctt atgataatca atatcatgta agtataataa acaagtagga
    25381 gaagtaatca tgaaaaaaat aaaatcactt gcaatattta tatctattat aactacgtta
    25441 gtacttgtta cagcatgttc agataagaat acagaggata aagataaatc agagacaaga
    25501 gttgtacaat ctgttaaagg agaggttaag ataccatcaa atcctaaaaa aatagttgat
    25561 atatcaggaa gtagtgaaga actattatta gcaggttata agcctgttgc aacagcaaat
    25621 gtagactcat atgaaactga taaattacca agttacataa gagaagagct taaaggtgta
    25681 aagatagttg ggcactcaat gatggatact atggatatgg aagctatatt agaagtaaat
    25741 cctgatttaa taataatgag tcaaagacaa gaaaaaatat atgaccaatt aaaagaaata
    25801 gctcctgtag ttatgatgaa agattatgca aatgactgga gaagcaagtt aactgatgtt
    25861 tcaaagttat ttgacaaaga agaagaagct aaaagttggc tacagaagta tgatgaaaaa
    25921 gctacaaagt taggtaagga agttatagaa aagaatggag aaaaaactta tttaccagtg
    25981 ttggcaagtt caggtcaatt tatggtattt agtgatggtg gaataggtac tctaatcaat
    26041 gatgatatga aattagctaa acctaagaat atgccaaaac aggatggaat aacactacca
    26101 atggtaagta tggaaggttt aacagatata gatgcagacc atatagttgt aattgctaca
    26161 gaagcagata aaaaagattt agaaaatagt gctatctggg ctcaaataag agcagtaaaa
    26221 gatggtaatg taacaatact tgatgctgct ccatttttca gtcaatcata caatccaatt
    26281 ggaaaagagt tattattaga atcagttaaa aatgaattaa caaagtaatt cttaacttag
    26341 taggtgtgag ataatgatat tcatttttca cacctatttt taataaatct taaaattaaa
    26401 atacttaata gatgatatta tactgacgat taaaagggaa aaggaggtag gataattgac
    26461 taagctgagt aaaaaaaata taacttattt gttgatatta gtaagtatag ttgtacttgt
    26521 atttggaatt gtattatcca taactattgg ggcaaaagat atgaatctat caactgttat
    26581 agatagtttg ataaaaatgg aagatggaat aaatatgaga atagtaaagg atgttagact
    26641 tccaagggca atagcagctg cacttgttgg aggattttta gcagtttctg gggcaataat
    26701 gcaaggaata acgagaaatc ctatagctga accatctgtt ataggaatta cacaaggagc
    26761 tacattcgca atttcgatat cactggtact tcaaaaaaaa cttcctcaac ttatacatgg
    26821 aagttttagt gtaatgatgt ttgcatttat tggagcaagt ataagtggat tatttatata
    26881 ttttataagt tctaaatcaa gaggaagagt taataatgta aaattagctc ttgcaggagt
    26941 cgctcttggt acattgctaa tttctttggc atcagcaata tctatgtatt ttaacctatc
    27001 tcaacaatta agtttctgga tatcaggagg gcttgtagga gtgaagtggg aaggtataaa
    27061 attgctattt gtagctggtg gtattggatt tattttagct attattatgg ctccaagaat
    27121 aactatatta agtcttggag aagaagtggc aataggatta ggacaaaaaa ctaactttgt
    27181 tagatttata tgtatagtac ttgtaatatt aatgactgga gcatctgtgt cagtgtctgg
    27241 taatattatt tttataggtc ttatagttcc tcaaatagct aaaggaatag taggttcaga
    27301 ttataagtat ataataccga gctctttagt attaggagct gtattgcttg tatatacaga
    27361 tatattaagt aggatgataa atcctccata tgagacacca gtaggttcta taacagcact
    27421 tataggagtg ccaatattta tataccttgt tagaaagggg gagaaatagg tactatgaaa
    27481 aatattataa aaataaattc taaaacatta cttgttatat caattttaat ggtgcttatt
    27541 tttatcactt ttttattgag tttaaatatg ggctcatttt ctatagaacc aatggatgtt
    27601 ataaagactt ttttagggca gggtcagcgt aatcatgaaa ttgcaatatt taaattaaga
    27661 ttaccaagaa tagtaatagc acttttggtt ggttctgcat tatcaacagc aggtgtaata
    27721 cttcaaggag ttacaaagaa tgatttagct gattctggaa ttttgggaat aaattcaggt
    27781 gctgcattgt ttgtagtagt ttatatatac cttatgaatg gtaatgtata tgaaggtatg
    27841 agtaacttga ctgtatttac aatgcctatt gttgcactta taggagcttt atttggagca
    27901 tttcttatat attctcttgc atggaaaggt ggtataaatt catcaagatt actacttatt
    27961 ggtataggtg taaacatagc ttttacttca attttgacaa tattccaatt gaaatttaca
    28021 acacaggaat ttaatagggt tatggcatgg acatcaggaa gcatttgggg aaccagttgg
    28081 aaatatgtaa tagctgtgct tccatttata gtgattttta tgggtataac tatttataaa
    28141 tctaaatata tagatgtttt aaatttgggt gatgaagtat ctataagtct tggtgtagat
    28201 gtagaaaaac aaagaagaag acttataata tatgcagtaa ttttatctgg tgtatcgaca
    28261 gcagtagcag gtagtatttc atttttaggt ttaatagctc cacatatagg tagaaaaata
    28321 ataggaccaa agcataaaag attaatacca gtatcagcat tgataggaac attattactt
    28381 ttaatagcag atactatatc aagaaatctt ctagcaccta tagaaatacc agtaggtata
    28441 gtagtttcta taataggagt gccgtacttt atttatttaa tgttggtaaa tgattaggaa
    28501 agggtgttgt tatgaactgt ataaatacta agaatctaaa tgtatcatat ggaaacacag
    28561 atattataaa aaatttaaat ttaaatatac caaaaggaaa aataactacc atcatagggg
    28621 ctaatggttg tggaaaatcg acaatactta aaactatagg tagaattatt agccctaata
    28681 gtgggaaaat atatataaat ggagaggaca tctacaaaaa gaagtctaaa gaaatagcaa
    28741 aagatatggc tgtacttcca caaagccctc aagctcctag tggtcttacc gtttcagaat
    28801 taatttctta tggaagattt cctcataaaa gtggatttgg taattctagt aaagaagaca
    28861 gagagattgt aaattggagt ttagaagtta ctggaattgc agaatttaag gatagaaata
    28921 tggaagattt atcaggagga caaagacaaa gggcatggat agctatggct ttggcacaag
    28981 aaactgatat attattactg gatgagccta caacatattt agatttggca catcaattgg
    29041 agatactaaa attattagat gaactaaata aaaaacaagg aagaactatt gtcatggtaa
    29101 tacatgaact taataatgca gcaagatttg ctgaccacat gataggtatt aagaaaggta
    29161 aaatagtttg tgaaggtgat gcatatgatg ttatgacgaa ggataatcta aaagaattat
    29221 ttaatattga tgcagaaata gcaacagacc caagaacaaa taaaccaatt tgtataactt
    29281 atgacatggt gtaaatggtg acaacatgga gaatcaagaa gcattaagac atgaaaaaat
    29341 atggatttta ttatttaggt attcgatacc tgcaataata gcaatgatgg taacttcact
    29401 ttataatgta gtagatagag cttttattgg ttctatggaa ggtattggct ctatagctat
    29461 tgcaggtctt ggtgtaacta tgccagtatt tactctaata atagcttttg gaatgttggt
    29521 atcagtaggt gctagcacaa gattgtctat aaagttaggg gaaagaaata gagaagaagc
    29581 agagaagata ttaggtaatg ctttgacact atctataatt atctctttaa ttataactat
    29641 attaggatta gttttcttag aagatatact ttttattttg ggtgcaagta aagattcaat
    29701 attttatgca aaagactata tgagtgtcat attggttgga agtatattta atttagttgc
    29761 attttctctt aataatgcaa ttagggcaga aggtaatcca aaattagcag caaggacaat
    29821 gattgtagga tgtgtattaa acctgatatt ggaccctata tttatatttg tatttaattt
    29881 aggtataaaa ggagcagcta tagcaacagt actctgtcaa atagtagtat tcttttgggt
    29941 aatacattat tttataagag ggaagtccaa tttaaaacta aaaaaatgta acttaaaatt
    30001 gaataaagat atagtaaaga aggtatttgc aataggaatg acaccttttg ctatggaagt
    30061 agctataagt ataactcaca tgtttacaaa taattctcta aaggtttatg gtggagattt
    30121 agctattgga gctatgacag cacttacatc tattttattg atgtttatga tgcctgtgtt
    30181 tggattgaat caaggtatgc aaactataat atcatacaat tatggtgcaa aacaatatga
    30241 gcgtgcaaag aaaactttaa tattatctat catagtgtca gttgtcatat tgtcatttgg
    30301 atttttagta gtacaagttt tcccagaagt atttgtaggt atatttaata aagattcaga
    30361 tttgatggat atagcagtaa gaggtataag cctaaatcta attacattgc ctataatggg
    30421 gatttctatt gtaggacctg tgtattttca gtgtataagt aaagttaaac attcaatgtt
    30481 tttaactctt ttaagacaat ttattttatt tataccatta atcattgtac ttccaattca
    30541 atttaattta gatggtgttt ggttggcaca gccagttgca gattttattg ctatgataat
    30601 tgtattatta ttcttaaaaa gggaatttaa aacaagccga gtgtaagaaa tttagaaaat
    30661 aaaattaaat tggaaaataa aaagacttgt ctttataaaa tgattaaaat tattttatag
    30721 agacaagttt tttattttat ttaaacggaa ctatccatac tggtttcttc tagttttttt
    30781 ccaaaagtca ttttctcaaa tatttcttga ggtagaggtt ttgaaaaaac atatccttgt
    30841 atcatatcac aattaatttt tttaagataa tccatttgca agattgtttc aacaccttct
    30901 gatatactat tcatatttaa tttttttgcc aaattaacta tagattctat tacatgattt
    30961 tcagcaatat tatctgcatt aggtgagcta aaaaaagcac ggtcaagttt taatgtgtca
    31021 acttttattt cttttaacat attgagtgaa gagtatccac ttccaaagtc atctagtgaa
    31081 cattgaaaac cttcttcatg gatttggtct attatattaa ttaatttttg gagattttca
    31141 aatacaagtg tttcagttaa ttcaatttct aagagcttag caggaatgtt gtatttatta
    31201 cgaagcattc tgtatttttc taaaaaatct atattattta aattagcacg tgaaaaatta
    31261 actgaaacag gtattggagt ttctccatta tctatccatt ttcttatcat actgcatact
    31321 ttttcaaaaa catagtggtc gagttttgta ataaaaccat ttttttcaaa gaaaggaata
    31381 aactcgtctg gtggtataag acctttattt gggtcttgcc atcttactaa tgcttctgca
    31441 cctacaatag tattatcttt gaggcttatt ttaggctgaa gatatactat aaattcgtta
    31501 ttatttaatg cttcctccat tctattttcc atttcttttt ctttaatcat ttttaaacgc
    31561 tctaaatcac tataaaaaac acatgtataa agtggatgat ttccaatgtt tcctttatta
    31621 ttttttcgtg caacatttgc acggtcttga attgaaacta aaggtagatt tgggtcatca
    31681 attttatata cacctataga tagagctata aaatatttac attcttcatt tttattgaaa
    31741 ctattaatat cattggtgat attttctatg tacttaagaa tttctttttg aggaatagtt
    31801 ttaataagta cattaaactg gtcattagaa actcgacaaa gcaattctcc tggttctaga
    31861 taattactaa tgacatcatg tatgtacttt aatgttttat ctcctgcttc actaccaaaa
    31921 gaatcattaa taagtttgaa tttctgaata tttatagata ccaatgaata gctttctgat
    31981 gaagatgact gtataatttt tttagcttca atatcaaaac gtgctttact gtaaccttta
    32041 gttacagagt ctacataggc gatttttata agttgtgccc tgttcttttg atttataaac
    32101 ataatcaata taataagcaa taaaaatagt ataacaatta aaatattgat gaagattgct
    32161 ttttttagaa gtaaatcaaa ctgtgcactt gctgtttttg ttggaacaat tgaaaggagg
    32221 tataagtttt cttcttgtaa tggaagataa tgcattgcct tagaaatacc atcatttaat
    32281 gtataataca tagaaccagt tttgttcttt tttaagttta ttttcatttc ttcaagttta
    32341 tttttatcaa cctgttttcc ttggtgttta atcatgtcaa aaaaatttac cacatttttt
    32401 ggagcatttt tgtttgctga acttacaata aaatttccat cttggtcgat aatttgggaa
    32461 aatccttcac catgaaagct ttctacactt aataaatttc tcatagtatc aatagtattc
    32521 caagcagcaa cagctccaac aattttatca ccattgtata gtggtacaga atataaaatt
    32581 ccatatgtac cagattgtga tttaacagga gtaattgttt ctttgccttg aagggctttt
    32641 ctataaaagt cttgtccttt aacattacct gtatctttaa gggcacttac aaaatttcca
    32701 ttagaatcta taatacctaa ccaatcaaat tcaaataatt ttaatttttt tgataagtat
    32761 ctattgactt ctttttcact atcattaatc tcaaaataag tatctcccat agaatatagt
    32821 gtcctaaata tacttttaca tttcacatta attgtagtgg aaatactttg tgaaacttct
    32881 acaagatatc gttctgtttc attatgtgtt actttattta gattcataat aaaagtgaca
    32941 catgttaatg acacgattaa aaggagtgtc aatagtaaag tagctattat ttttttattt
    33001 tttgtgtttt caaagttcat tcttttgttt catcctccat cctttatttg tttacaaata
    33061 agaattctct cagacatatt ataccaaata tcttttcata caaagatatt aaattttatt
    33121 tatcccactt tacatttagc tttatttatg tcttcttaga gattaatcaa gatacgttta
    33181 ttgtttaaat cttattttat aatattttga gtaaaagagg ttaaaaaagg aactgttttc
    33241 aaaataattt tgatacagtt ccttttcagt atagaaaatt tttatagtat tagaaagaac
    33301 ttttagctta tgtatctaca taagtattat atttataaaa gatattttgt tacaatctaa
    33361 aatgtagatg aaattctgta aatgccaaat tctctatgac caagactttc agctttggta
    33421 tgtttaccat tacagacttc tattatttca ttaaatattt cttgacctat atctgctatt
    33481 ttagcaccat ctgttataat tctacctgca tttatatcga tattgtctgg cattttgttg
    33541 tatgtatcac tattcccagt gattttaata actggtgaaa tagggcttcc tgttggagta
    33601 cctctaccag ttgaaaagat tacaatttgt gcaccacctg ctaccatacc agtgatagaa
    33661 tctatatctt gacctggagt atccataaaa tataatcctt ttttatcagg aggtacaata
    33721 tcagcatatt caagagcacc tttgaatggc ttattgcctg ccttatacat acacccaagt
    33781 gacttttctt caattgttga aagtccacca gctttattgc ctggagtagg ttgaccacta
    33841 cgtaaatctt ctcccatagc aattgctctt ttttctacat cacttacaaa tttaagaaac
    33901 ttatctttca tttcttcatc ttcaaaacgg gtagccaaca aatgttctgc accaattact
    33961 tctgtagttt cacttagtat gctacttcca ccttcatcta caagaaggtt tgatgcaacg
    34021 cctattgaag ggtttgaagc tattccactt gttgggtcag aaccaccaca ttcaagtgct
    34081 aatgtaattt cactcatacc aaattcaact cttacttctt ttgatacttc acgagccatt
    34141 ttacttacta tttcagctcc cttagaaact gtttttaatg ttccaccaca ttcttgtata
    34201 acaacgtaat ttaccttttt tcctgttgta gctatttcag atgctaattc ttttgcttga
    34261 ataccatcac atccaagacc aactactaaa actgcggcaa cattaggatt ttttccaaat
    34321 cctattaatg tctttgctgt aagctctata tcagaaccaa tttgacaaca tccatgttga
    34381 tgagggattg ctattgctcc aggcacaagt gatgctattc ttgtagctgt ctcacttgaa
    34441 catacagatg ttggaataat taaaacatga ttacgaatac caaactgacc attttctctt
    34501 aaataaccca ttaatttcat tttaacttcc tcctattttt tatctccacg accacgtgta
    34561 ctttcaatgt tatgtacatg aacatagtca ccagttttta tgtcaactgt tgcaattcct
    34621 ataatttcac cgtatttgta tacaacatca ccttttttta catcttctgt agccatctta
    34681 tgaaagacag gtatattatc atttactatg taagactttc catcaattga aactttttca
    34741 cctttaatta aaggtctgac acatgtaact agattatctt tttcatttgc atgaataatt
    34801 gcattcatta attttacctc cttaagtatt aatttacttc aatattttta tttgttttaa
    34861 aaatagattt tttctttttt tctcttttat ctagatagga aactaacatt ggacaacata
    34921 ttgctgtaac aataatagca gcagcaactt gtactgttga aacagctgct attgtagcta
    34981 gagtagggtc tatagctgct aaagcttcag gagtaccagc tgcatttccg gctgttgtac
    35041 ctgtagctgc acctactgct ggatgttctg cacgtataag tttcattaca aagtacccac
    35101 ccatacctgt tattatagta actcctaaac caagtacaac tccaggtagt ccagcagtta
    35161 taatttgatt aaagtttaat gctgctccta aaggaaaagc gaagaaagga attaataatg
    35221 ttgtaccagg tgcaagaaat tctcgtatat cttcatcaag gttaccaagt ataaatccaa
    35281 gtagtattgg tataagtgct gcaaatagtg ctactatagg tacatttgca agtccagtta
    35341 ctccaaaagc aagcattgta aaaaaaggac catcatttag agataagata gatattgctc
    35401 caacatctgt ggagtctcca tattcacctg caagagcagc aaatagacct ccatttgaat
    35461 tagtcatggt agcaactatg gcaagaggtg taataccaat tataccttta ggtccaataa
    35521 atttactaac aataatacct aatactgcac caattataaa ttttgttgct gtaagtacta
    35581 tacctttagt caatggttta ccagcttgtc tgatattgat ttgagctcca ttgcatagac
    35641 aaaatagagc aagtatactc attgcaccag ttttaaataa ggatgttgtg aatcctccaa
    35701 tttcaagagc ttgtggacat actgtattaa atagtgctcc caataacaag ggacagacca
    35761 taagtcctcc tggtatcttt ttcactgatt ttaagatgtg catctagtat cactcccttt
    35821 catttttata taggtattat aaaagcaatt actatgccaa tatatagagt ttgtatcttt
    35881 agttatcatg attattttta ataatcgatt gaaatgctgt agattactta taattaaaag
    35941 tatgattgac gagaatttca cttacaaaga ttctttttag catataattg tattttttat
    36001 tgaaaacaaa taaacgtctt atgtattaaa attaaacata
//
LOCUS       DAYAKB010000035        35567 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.035, whole genome shotgun sequence.
ACCESSION   DAYAKB010000035 DAYAKB010000000
VERSION     DAYAKB010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35567
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.035"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            387..953
                     /locus_tag="ACGI3L_002069"
     CDS             387..953
                     /locus_tag="ACGI3L_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HFG9197778.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            1258..1719
                     /locus_tag="ACGI3L_002070"
     CDS             1258..1719
                     /locus_tag="ACGI3L_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9197779.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1787..4033
                     /locus_tag="ACGI3L_002071"
     CDS             1787..4033
                     /locus_tag="ACGI3L_002071"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197780.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            4026..5858
                     /locus_tag="ACGI3L_002072"
     CDS             4026..5858
                     /locus_tag="ACGI3L_002072"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197781.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6583..7854
                     /gene="hflX"
                     /locus_tag="ACGI3L_002073"
     CDS             6583..7854
                     /gene="hflX"
                     /locus_tag="ACGI3L_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFG9197782.1"
                     /translation="MAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSITQN
                     AKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRTAL
                     ILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKLEL
                     DRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLVDI
                     FKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRSTL
                     EEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVLDR
                     ILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNENTS
                     IINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            8087..8584
                     /locus_tag="ACGI3L_002074"
     CDS             8087..8584
                     /locus_tag="ACGI3L_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9197783.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8634..9158
                     /locus_tag="ACGI3L_002075"
     CDS             8634..9158
                     /locus_tag="ACGI3L_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HFG9197784.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            9470..10834
                     /locus_tag="ACGI3L_002076"
     CDS             9470..10834
                     /locus_tag="ACGI3L_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HFG9197785.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10973..12139
                     /locus_tag="ACGI3L_002077"
     CDS             10973..12139
                     /locus_tag="ACGI3L_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9197786.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            12256..13038
                     /locus_tag="ACGI3L_002078"
     CDS             12256..13038
                     /locus_tag="ACGI3L_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9197787.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(13157..13810)
                     /locus_tag="ACGI3L_002079"
     CDS             complement(13157..13810)
                     /locus_tag="ACGI3L_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9197788.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13834..15198)
                     /locus_tag="ACGI3L_002080"
     CDS             complement(13834..15198)
                     /locus_tag="ACGI3L_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HFG9197789.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            15856..17286
                     /locus_tag="ACGI3L_002081"
     CDS             15856..17286
                     /locus_tag="ACGI3L_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9197790.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            17389..18492
                     /gene="hisC"
                     /locus_tag="ACGI3L_002082"
     CDS             17389..18492
                     /gene="hisC"
                     /locus_tag="ACGI3L_002082"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9197791.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            18525..18743
                     /locus_tag="ACGI3L_002083"
     CDS             18525..18743
                     /locus_tag="ACGI3L_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9197792.1"
                     /translation="MNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAHVEVDES
                     KCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            18760..19809
                     /gene="vorB"
                     /locus_tag="ACGI3L_002084"
     CDS             18760..19809
                     /gene="vorB"
                     /locus_tag="ACGI3L_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HFG9197793.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            19811..20551
                     /locus_tag="ACGI3L_002085"
     CDS             19811..20551
                     /locus_tag="ACGI3L_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HFG9197794.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            20554..21093
                     /locus_tag="ACGI3L_002086"
     CDS             20554..21093
                     /locus_tag="ACGI3L_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HFG9197795.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            21217..23316
                     /locus_tag="ACGI3L_002087"
     CDS             21217..23316
                     /locus_tag="ACGI3L_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HFG9197796.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMEKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(23583..24098)
                     /locus_tag="ACGI3L_002088"
     CDS             complement(23583..24098)
                     /locus_tag="ACGI3L_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HFG9197797.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(24190..25401)
                     /locus_tag="ACGI3L_002089"
     CDS             complement(24190..25401)
                     /locus_tag="ACGI3L_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9197798.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKFLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            26077..27519
                     /locus_tag="ACGI3L_002090"
     CDS             26077..27519
                     /locus_tag="ACGI3L_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9197799.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            27561..27914
                     /locus_tag="ACGI3L_002091"
     CDS             27561..27914
                     /locus_tag="ACGI3L_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197800.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            28105..28926
                     /locus_tag="ACGI3L_002092"
     CDS             28105..28926
                     /locus_tag="ACGI3L_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HFG9197801.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            29184..31067
                     /locus_tag="ACGI3L_002093"
     CDS             29184..31067
                     /locus_tag="ACGI3L_002093"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFG9197802.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            31291..31971
                     /gene="pgmB"
                     /locus_tag="ACGI3L_002094"
     CDS             31291..31971
                     /gene="pgmB"
                     /locus_tag="ACGI3L_002094"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFG9197803.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            31968..34253
                     /locus_tag="ACGI3L_002095"
     CDS             31968..34253
                     /locus_tag="ACGI3L_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFG9197804.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLLYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKCIKIDK"
     gene            34478..35371
                     /locus_tag="ACGI3L_002096"
     CDS             34478..35371
                     /locus_tag="ACGI3L_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFG9197805.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT        13919 a         3852 c         6192 g        11604 t
ORIGIN      
        1 aaattttcta ttttatatat tgaacaattt atgtgaatag aaaatttttc aataagactt
       61 ttgagtttaa tcattatatt ggtaaggtaa acatttttaa atctaattat atataggtga
      121 aataaaaaat taattataag taaggcattt agaataaaat tttaaaaaaa ttataattaa
      181 aaaaataatg aaaatatata atattagttt agattataaa aaataaatat acaaatactt
      241 ataaatacaa gttatataca agatttatag tagagtaata atcttataaa ataatttaat
      301 aaatataaat taaattatat gtgtatatat tgtactttaa tagtgatata ataataaaaa
      361 aatttttaaa gagggtgata ttacatatga gaaaacttga agagatatta gaatataata
      421 aatcatttgt agagaacaaa gaatatgaac aatatgtgac atcaaaacat ccaaataaaa
      481 aaatagtagt cttatcttgt atggatacaa gattaactga gcttttgcct aaggctatga
      541 atttgaaaaa tggagatgtg aaactaataa aaaatgcagg agctactata atgcatcctt
      601 ttggaagtat tatgagaagt gttttagttg caatttacga atttgatgta gatgaggtta
      661 tggttgtagg gcatcatgga tgtggtatgt gtaatgttga tacggataag ttacttggta
      721 aaattttaga tagaggaata tctaatgatg taatacttac acttcgtagt gctggaattg
      781 atacaaaaca atggttacat ggattcgatt ctgcagaaga atctgtaaaa gatagtattg
      841 atttaataaa agggcatcct ttaattccag atggtattat tgtacatggt ctaattatat
      901 cacctgaaac tgggaagtta gacgttgttg taaatggata tgaagataag tagagtatca
      961 taatgttata taatcaagat actgttgaat atgatgttgt ttcaaaattt attttgggac
     1021 aactttttta tttgaaaata tatgaaaagg tttattttaa gctttacaat aaaaaatata
     1081 agtagctgac taattaaaaa tcttactatt atttattaaa attataacta tatgatataa
     1141 aaatatttaa taaatgaaat ttatatgaat tttttataaa tatattgaaa aaatgcatgc
     1201 agtatagtaa aataatgctt agccgactaa gtaatataaa aaataaggag ggcaagtatg
     1261 aatagcaatt ctgaagaaaa attaaatgat gttttcttgc aattaatgcg aatatatttt
     1321 ataagaactc atttttattt tgataaatta ggcttatatc atggtcaacc ccaaatactt
     1381 ttttctttaa agatgaaaga tgggcaaagt caaaaagaat tagcagataa aaggaaagta
     1441 aaagcatcta caactacagt tatgataaag aggatggaaa aagctggact tgtggaaaga
     1501 aaacaagatg aaaaggacca aagagtatct aggatttttt tgacagacaa aggtttagaa
     1561 atatgtaata aagttgaaga atttaacaag gaattggaaa gagagttttt tttaggattt
     1621 agtgaagaag aaaaaatagt acttagaaga cttctaatgc aagtacgaga taatttaaaa
     1681 gcaggatgtc ataagcatga agatgaaaaa tatttttaaa gtttaaaata atgtttttca
     1741 atttaatgtt attagactaa ttaatattac agaagggaag aaatgtatgt ttaaattaat
     1801 taaatattta aagaaatcgg cattatcaat agtaataata gtctgtctat tggtaattca
     1861 agcggtatgt gacctttctt taccagaata cacatccaat atagtaaatg taggtataca
     1921 acaaggtgga gtagaaaact ctgttccatc tgtgattaga gagagtgaat taaataaaat
     1981 tactttattt atggataaaa gtagtaagga taaagtacta gataattata ctttgctgaa
     2041 taaaaaggat tatgttaagt ataaagataa gtatccaggt ctaaaagatg aatctcttta
     2101 tgagttaaat actaaagaca aagacactat agatgattta aatgttattt ttggtaaagc
     2161 tattttaata gtatcagggc ttgagggcga tagtaaagag gtaaaagcta tgaaagctca
     2221 gttaatgagc aaacttccac cacaagctac tcaaagtgga gatgttgata tatttaaatt
     2281 gttatcagca atgccaaagg aacagttaga tacattgact aaagagatga gcaaaggctt
     2341 tgaaagtatg ccagagagta tgataacaca aagctctgtt tcatatgtaa ggtcagaata
     2401 tgagaaaata ggtattgata cagaaaaaac tcaaaataat tatatattat ttactggtgc
     2461 taaaatgctt ggtatagcaa tgattagtat ggtagctaca ataacagtag gatttttagc
     2521 agcaagagta gccgcaagtg taggtagaaa tttaagaagt ggagtattta gaaaagttat
     2581 gtcattttca aatactgaaa tgaatgaatt ttctacagct tcattaatta ctcgtagtac
     2641 aaatgatatt caacagatac aaatgttgat ggttatgttg cttagaatag tattctatgc
     2701 acctataatg gctataggtg gagtgataaa ggttttaaac acaaatactt caatggcctg
     2761 gattatagca gtagcagtag ttgctatctt atcattaatt gtagtgttat tctcagtggt
     2821 tatgcctaag tttaaactgg ttcaaaagct tgttgataag ttaaacttag taagccgtga
     2881 aataattact ggtattccag ttatcagagc ttttagtact gaaaaacatg aagaagaaag
     2941 atttgataaa gcaaataaaa atttaactaa aacaaatctt tttgtaaata gagttatgac
     3001 atgtatgatg cctgctatga tgcttataat gaaccttatc acagttctta tagtttggag
     3061 aggtgcatac agtgttgatt ctggagcaat gcaagttgga gatatgatgg catttataca
     3121 atatacaatg caaataataa tgtcattctt aatgatatca atggtatcta ttatgcttcc
     3181 aagagcatcc gtttcagcta cacgtataga tgaagtatta gtgtcagata taagcataaa
     3241 agacccagaa aaatcagagg cacaagagtt taaggaagat aaaaagggtc ttgttgaatt
     3301 taaaaatgtt tcgttcatgt atccagacgc agaagaacct atattaacaa atatatcttt
     3361 tacagcaaag ccaggagaaa caactgcctt tataggaagt actggtagtg gtaagtcaac
     3421 tcttataaat ttaattcctc gtttctttga tgttactgaa ggagaaatat tacttggtgg
     3481 agttaatata aaaaatgttt ctcaacatga tttaagggaa aaaattggat atgtacctca
     3541 aaagggagta ttgttttctg gtactataga atccaactta aaatatggta gaaaagacgc
     3601 aacagatgaa gaaatgagaa cagcagctga aatagctcaa gctacagaat ttatagattc
     3661 taaaccggaa gcttttaaaa ctgaaatttc tcaaggtgga acaaatgtat ctggaggtca
     3721 aaaacaaaga ctttctattg caagagcaat agcaaaaaat ccagaagttt atatatttga
     3781 tgatagtttt tcagcacttg acttaaaaac tgatgcagct cttcgtaagg ctttaaaatc
     3841 aaaaactgct gaaagtacag ttctaatagt tgcacaaaga attagtacta tcttaaatgc
     3901 agaacagata attgttttaa atgagggcga aatagttgga ataggaacac ataaagagct
     3961 tctaaaaaat tgcgaagttt atgagcaaat agctttatca caactttcaa aggaggagct
     4021 agctaatgag tagaatggga agaggtccta tgggaaaatc tatgggagca ggacaaaaag
     4081 caaatgactt taaagggact atgcgaaaac taattgcata tttatctaaa tttaaaatat
     4141 caataattct agtaattgta tttgctattg gtagtgcgtc gttttctata gtaggtccaa
     4201 aaattttagg aaaggcaact acaaagatat ttgaagggct agtgagtaaa gtttctggag
     4261 gaaacgtagg tatagatttt aatgcaattg gaaaaatctt aaccttttta cttttccttt
     4321 atttgataag tgcactgttc tcttttatac aaggatttat aatgagtgga atttctcaaa
     4381 aagtatccta taatttaaga aaagagattt cagcaaaatt ggatagattg ccaatgaagt
     4441 attttgatac taagacgcat ggtgaaatat tatcgagaat tacgaatgat atagatactt
     4501 taaatcaaag tttaaatcaa agtatgacac agcttataac atcagtaaca actatgatag
     4561 gtgttttgat aatgatgtta tctataagtg gaattatgac attagtggca gttttaatat
     4621 taccaatatc aatgtttgta atttcaagaa taataaagaa atcacaaaaa tactttagat
     4681 atcaacaaga atatttagga aatgtaaatg gtcaagttga ggaaacttac agtggccaaa
     4741 caatagtaaa agcatttaat cgtgaggatg aagtaattga agagtttgat aaactaaatg
     4801 atagcctgta taattcagcg tggaaatctc aatttttatc aggtataatg caaccactta
     4861 tgatgtttat tggaaacttg ggatatgtaa tggtatcaat cttaggaggt tggcttgcaa
     4921 ttaagaaaac aattgaggtt ggtgacatac agtcatttat acaatatgta agaaacttta
     4981 cacagccaat gactcagatt gcacaggttg ccaatttatt gcaatcaaca gcagcagctt
     5041 ctgaaagagt atttgagttt ttagaagagg aagaagaagt ccaaattgtt gaaaatgcag
     5101 tttcaataga tggtttagaa ggtaaaattg attttgaaaa tgtcaacttt ggatataacc
     5161 caaacaagac tataataaat gatttctcag taaatgttaa acctggtcaa aaagttgcta
     5221 ttgttggacc tacaggagca ggtaaaacta caatagttaa actgttaatg agattttatg
     5281 atgttaatag cggttcaata ctgattgatg gtcataatat taaagatttt aatcgtagtg
     5341 agcttagaga aatgtttggt atggttcttc aagatacatg gttatttagt ggttcaatta
     5401 tggaaaatat aagatatggt aagttgaatg ctacagatga agaagttata gaggctgcta
     5461 aatctgcaca tgttcataga tttattaaga cattaccaga tggatataag atgaaattaa
     5521 atgaagaagc aagtaatgtt tctcaaggtc aaaaacaatt attgactata gctcgtgcta
     5581 ttttagctga tcctaaaatt ttaatattag atgaagctac aagttctgtc gatactagaa
     5641 cagaagtatt gattcaaaaa gctatggata atcttatgga aggtagaaca agttttgtta
     5701 tagcccacag attatcaact atacgtgatg ctgatatgat tcttgtaatg aatgaaggag
     5761 atatagttga acaaggaaat cacgaggaac ttctaaagaa aggcggattc tatgccaatc
     5821 tttacaattc tcaatttgaa gaagatgaag caatgtaaca aaaaactatc ttagcataga
     5881 catgtaatta ataagataaa ataaatgagg gtgccttaaa atgaactttt taattcataa
     5941 ggcactcttt tgtgtatgaa ataaagtgta tttttatcat tttaacaatg aaaaagagga
     6001 ttctctatat tttgagatag ccacataatt ttatgtcttt acaaagtgtt tattttatta
     6061 taatatgtag taaggaaaat gttggaggtg attatcaaaa tgtatattta attttattct
     6121 ttaaatttta ttataaatag aatttaattt taatagttga tgattatatt gaagtatatg
     6181 tttttattac ttttattaat catgcaaata actacttaaa tttaagaata gggttaaata
     6241 taaaatgata attacatata agttaattaa actaatgtat ttttaatata tatttagaat
     6301 tttaatcctt cttatgatat aagtagcttg ttttgtatta cttagatttg taaggagttt
     6361 ttttattgaa aaaactgcat aatatatttg ggaggaggtg taagaaagtg attttttata
     6421 taagattgag aaaataatgc acgattatgg ttattataat agtaaataag aagtgtcatt
     6481 taaggataag ataaaaagca aaattcttga tgaatttaat tatagagcca taatctcgtg
     6541 ctatagatta aataaaaaat agcagataag gagaatatgg atatggcgaa aaaaggaata
     6601 acagtaggat taaacataaa taataaatct gaggacttta atgaactaat gattgaactt
     6661 gaaaacttat gttcagcatg tgatattgat gttgtaggga gtataactca aaatgcaaag
     6721 caggttaata gagcatttta cattgggaca ggtaaagttg aggaaatatt aaacttaata
     6781 aagaaagaaa atatagagat agttatattt tacaatgaac tttctacatc acaactaaaa
     6841 aatcttgaag aaaagcttaa ttgtgaaatt atagatagaa cggcattgat acttgatata
     6901 tttgcacaaa gggcaaaaac tagagaagct aaacttcaag tagaagtagc aagtttaaaa
     6961 tatatgttac caagacttat aggttcaaat gaaaatttag gacgtcaaag tggtggagtt
     7021 ggtactaaaa atagaggttc tggtgagaaa aaattagaac ttgaccgtag aagaatagaa
     7081 gaaaagataa catctttaaa tagggagttg gatgatttaa aattccaaag agaaactcaa
     7141 agaagtatga gaagaaaatc aaatcttcca aatgtagctc tagtcgggta tacaaatgct
     7201 ggtaaatctt caataatgaa taaactagta gatatattta aaaactctga agaaaagaaa
     7261 gtgtttgaga aaaacatgtt atttgctaca cttgaaactt ctgtcagaaa tatagttctt
     7321 gcaaataaca aagaattttt attatctgat actgttggtt ttgtaagtaa tctaccacat
     7381 gacttagtaa aagcatttag gtcaacatta gaagaagcat gtgaggcaga cgtactgtta
     7441 catgttattg atatttcaaa tccaagctat aaaagtcata ttaaagtgac agaagatact
     7501 ttaaaacaaa taggtgcaga tggtatacct atgatacatg tgtataataa aattgattta
     7561 atagatgtag aagtattgga tagaatttta gatagtatcg ataaagaagg tatatttgtt
     7621 tcagttaaaa aagatataaa tatagataaa atgataaaat gtatttgtga tagcatattt
     7681 aaagattatg taagatgtaa gttcttaatt ccatatgata aaggtcatgt agtttcttat
     7741 tttaacgaaa atacgagcat tataaataca gaatacagag aagatggagc tattttagat
     7801 gtagaatgta gcaatataga atataataag tataaaaagt atgctttaga gtaaattttg
     7861 aaaaacttat tatagcctaa aatatattta atttataatt tattataaat tgattgtaaa
     7921 tatgatttta tgaaacggta tagccataat gctatgccgt tttgccgttt ataataaaaa
     7981 taaatttatt gacataatag taactaatta ctataatata aagtaattag ttactattta
     8041 aaattatcaa aaaattaaaa tctaagataa agagaagtgt ataataatgg atgcagaaag
     8101 tttaatgaaa aaatatatgg tagatgatga tagtagaaaa caagctatat ttgcaagtat
     8161 atttgtaatg caaaataaac ttcaaactac atgtgataaa ttagacccag aattaacaat
     8221 gaaacaatgg ttacttttag ctattgcgga ctctgtagat gaaactctta cattaaccaa
     8281 acttggagaa ttaatggggt gctcaagaca aaatgtaaaa aaactagcta ttgctttaga
     8341 aaagaaaggt tttatacaaa ttgagcagaa tgaaaaagat tcaagagcta tctgtcttgt
     8401 gacaaaagat agagtgcaag agtattctaa aaaagtaaga ggtatgcagg aaaaagtatt
     8461 acagctttta tttgaagatt ttacagagaa agaagtggaa cagttatttt ttggaattat
     8521 gaaattaagt ataggaattg aaaatgtgaa aaattatgta gaaaataatg acgttggaga
     8581 ataagcaagt atcaaatcaa ctttgtatga catcagagag ggggataatt tatatgaaaa
     8641 atgtagtagt gatttataag agtaagtatg gttcaacaaa aaaatatgct aaatggcttt
     8701 cagaattatt gtcttgtgat atttttgaaa ctaagaatat taatatagaa aaggttatga
     8761 agtatgatac gattatttta ggaggaggtc tttatgcttg taatatagcg ggaatttctt
     8821 tcttaaaaaa aaattataaa gaattgcaga aaaaaaattt agtagtattt ggcgtaggag
     8881 ctgctccata tgatgatgaa gtaataaaga aattaagaga agtaaatttt aaggatgaat
     8941 taaacaaaat tccttgcttt tattgtcgtg gggcatggga tgagacaaaa atgtctttta
     9001 tagattatac tctttgtagt ttttttaaaa aatctatagc taaaaaagaa cgtcaaggtc
     9061 ttaaaccagc agaagcacct ttattgtctg gagaagcctt tgattggtgt aataaagaaa
     9121 atttaactcc aatacttgat tatataagag aactttaaga ggtatatatt tgtaattatt
     9181 tattatctaa agttagattt catagaaact tactagacat tatttataaa ataatattat
     9241 taaagatgga taatttaatt gtttcaataa ggttataatt ttaaaaaatg tttattttaa
     9301 aataaactat tttataagct tacttatact taataagggg ctttttttat tggaagattt
     9361 atgttatatt gagatgaatt tattatgata taaaaaataa tgttaggata aatttaaatc
     9421 tttttctaaa aatgtattag tataattctt aaagaaagga tttttaacaa tggatataaa
     9481 agagttagtt aaaatgcaaa gaaaatatta taatacaggt aaaacaagag atatatcgtt
     9541 tcgtatagaa cagttgaaga aacttaagtt agttgtatca caaaatgaag aaaaaatact
     9601 tttagcacta aagaaagatt taaataaatc ggattttgaa ggttttatga cagaggtagg
     9661 catgttttat agtgaattaa actttgctat aaagaatata agaaaatgga gcaaaataaa
     9721 aagagttaaa tcaagtatgg ttaattttcc atctatatcc aaagttgttc cacaacctta
     9781 tggtgttact ctcataatgt caccttggaa ttatccattt caattagcac ttataccatt
     9841 agtttggtca ttagcagcag ggaattgtgt tatattaaaa ccttctgaat attctgtgtc
     9901 aacatctagt gtagttaaag acatagttga agatactttt tcaaaagaat atgttgcagt
     9961 tgttcaagga agtcaagaag aaagtgaaaa gttactattg gaaagatttg attatatatt
    10021 ttttacagga agtactaatg ttggtaaaat aatcatgaaa tcagcatcag agcatttaac
    10081 tcctattact ttagaacttg gaggaaaaag tccttgtatc attttaaaag atgctaatat
    10141 agaccttact gccaaaagac ttacttgggg aaaactaata aatgcaggac aaacctgcgt
    10201 ggctccagat tatgttttag tgcatgaaga tagaaaaaat gagttaatag agaaaataaa
    10261 atattatact aataagtatt ttggggataa tgcatgtaat aatgagcaat ttcctaaaat
    10321 cataaatcag agacatttta atcggatatt atctcttatt gataaagata agatagtcta
    10381 tggtggaaat tataataagg agacattaaa gatagagcca actatagtag acaatgttaa
    10441 ttgggatgat aatataatga aggaagaaat atttgggcct atatttccca ttttaacata
    10501 taaagattta gatgaagtaa tacaaaaaat tatacaaatg ccaaatccat tggcacttta
    10561 tatttttaca aaaaataagt acctagaaaa taaactttta gaaatgattc cagcaggcgg
    10621 atgttgtatc aatgatacag ttactcatat agctacgaat tacttacctt ttggtggtat
    10681 tggtgaaagt ggtatgggct catatcatgg aaaagctgga ttcgatacat ttactcacta
    10741 taagagtgtg ttaaaaaaat taaatttgga tgtccctatt agatatgctc catacgataa
    10801 taaattaatt aaggttctta aaaagataat gtaggttata ttgtagaata ataaatataa
    10861 ataaaattga gtatttgtat tctgaatata ttttattttt aatttggtat atttgttata
    10921 aaagtggtga ttttgtgata aaatttaatt atatagaaat aaggaggaaa aaatgaaaat
    10981 taattggaat acaaaataca caacaatagc aatttataca tttataatag ctgctagtag
    11041 tattatattt tatctagtat catcacaaat tgatgtattt tctaataatt tagatgctat
    11101 atttacaaca ttacaacctt ttataatagg atttgctatt gcatatcttc ttaattttat
    11161 tttaaagttt tatgaagaca gaatttttat aaaaagtgag aaattaaaaa aactaaaaca
    11221 aagttcaaaa agaggcttgg gtcttttatt aacatatgca acagctacat tgatacttta
    11281 cttatttatg catttcgtat tgccacaagt aattgagagt attgttggac tagcaaatga
    11341 tatacctatg tatgtaaaca atgcaactaa gcttattgat aaattaatga ctgatttaaa
    11401 tcttgatgag caatacttta atttggcagt tgataagtgg aatgaatttg ttacatatat
    11461 tataaagttt gtaacagatt taatcccaat attaggaagt atgttaaaga atgtagcctc
    11521 tagtatatgg aatattgtac taggattaat tgtttcagtg tacttattaa ttgataaaga
    11581 aaaattctat ggattaagca aaaaaataac ttatgcagta tttacagaaa aacaagctgc
    11641 cagaatttta gaattaactc atagaagtaa ctatacattt ggaagatttt taggtggcaa
    11701 aatattagat tcattcatta taggtattct aacatttgta atacttacgt tagttaaaat
    11761 gccatataca ttattaatat cagttataat tggtattaca aatattatcc ctttctttgg
    11821 acctttattt ggagctatac catctacgct aatagtgatg tttgtatctc ctataaaagc
    11881 tttctggtta ttgttgatta tattaataat acaacagata gatggaaata ttataggacc
    11941 taaaatactt ggagattcaa ttggtatatc tgcattttgg attttgttct ccttattggt
    12001 tgcaggaaaa ttattaggtt ttattggaat ggttatagga gttccaatgt ttgcagtaat
    12061 ttattctata attaaggata ttgttgaaag taaattggac aaaaagggat taccgacaga
    12121 tacttccgat tatatgtagc taaaaaatat tatgtataat taaaaatata taaattaagc
    12181 aatatttaaa gcactgagaa agttaaactc ttggtgcttt ttagatataa aattattata
    12241 gaagaggtgt tttttgtggc atttatagaa tgtaaattta aatctaaata tactggagga
    12301 gaaactgata taattgtaat tttgcctgta gcaaatggaa aagaactttt tagtggtaaa
    12361 gagatatatg attttgaagg taaatttaaa acattatact tatttcatgg tttagaagat
    12421 gaccaaagct catggattag atatactaat gtagagcatt atgctaaaaa taaaaatata
    12481 gccctagtaa taccaagagt agaaactagt ttttatactg atatggcgta tggacaccaa
    12541 tattttactt ttgtaagcga ggaattacct aaatttgtta gagctatatt tcctttatca
    12601 gataaaaggg aagataactt tgtagctggt atgtctatgg ggggatatgg agctttaaaa
    12661 ttagcgcttt caaaaccaaa agagttttcg gcagttgcaa gtttttctgg ttcgcctgat
    12721 atgattcatg agttagaaaa tcaacaaata gaaaccaatg cagacattct atttcacgat
    12781 tttggtagac cagaagacgc tagaaatagt gagaatgatt tactttacat acttaagaac
    12841 cttaaagaaa gaaatgaaga tattcctaaa atttatcaat tttgtggtga tagagatttt
    12901 ttatataaaa ataatcagat gtttaaaaaa tatgcagatt ctctgggtgt agatgttgaa
    12961 tatgaagagt gtgtaggggg gcatgaatgg cgtctttgga atttatggat aaagaaattt
    13021 atagatataa ttggatagta cacttatggt attaacaggt atactataaa atatctttaa
    13081 atatgataaa gactgaaatc ctaaaatcaa attatgattt taaaatttca gtctctaaga
    13141 atttaataaa attttattaa gttcttacac gagttattat tggagtaaaa ttgtcaacta
    13201 tatctatata gtatttactc aattcctcta aaatctcttc gcataaatcc gtactatgac
    13261 caagattaat aagaaactgt tttgtaaaat gctttattac agcttgagaa gatatatcgt
    13321 acttgtgtga agtataaact ctaattattt caggtttcat agcaagtata ccaatacaag
    13381 aaagtattaa ttcatcatgt tctatagatt ctttatcatt aacatatctt ttcatgacca
    13441 tttcggttac acttctttga tagcttaaaa tagcttcttc ataagctata tccaaataaa
    13501 aatttctata tgcttcgttt tttagaagga aacaaaggtc agcattcata gcaagaaaga
    13561 acatcatcat agtaccttct tcatggtagt tatagattaa agactgcatt tcatttctta
    13621 tatcttcata tattatagct cctatttcgc ttttacttga gaagtaatag cttattagac
    13681 ctaaatttat attagctctt tctgcaattt gcctagttgt tgtcttatga taaccttgct
    13741 caaaaaataa ttctctagca gcacttataa tactagcttt tgtttctttg cccttttctg
    13801 attttgacat atttactgtg tatacctctc ttttcaatct ttttttgaaa atttgctaac
    13861 tataaatatt gtaatagaac cacctattat aggaaccaaa attctgtcaa atacagtaag
    13921 aataccaatc atatttaata atgccaatat aacacttact ataacagcat agatagctcc
    13981 tttttttgta gcacctttcc agcaaagacc aattacaaat ggtgcaaata ttacacctgt
    14041 acataatgga gctggccaaa acaataattc taataaacta tcaaatttaa gtgctatgat
    14101 tgcacctatt atagctgtca aagctgatgc aatttgagaa tactttagag tattttttaa
    14161 atcattaaat tctatattag gatgtaataa tttgttataa atatctcttg atataatagc
    14221 actcattgag gtcattaatg aatcggcagt agacattatg gcagccaata tagcagctaa
    14281 gaataataca gatattaaag gtggcaaagt agtcgatatc atttgaggta aaacctgaac
    14341 agatgatata tttggaaata aactaccacc aatagctcca attattccta tagggaaagc
    14401 aagaaataat agtataaatc ctgcaattac actactttta actgcatttt tagcattatc
    14461 agcacattga tatcttaaaa aactttcata agaaaatatt gagcctaaaa ctaatggtaa
    14521 aactgtatac ataaaatcac taatcgattt atttcctgga aagaatggtt cttttaccat
    14581 tgattgtaac ataagtaaag ggttgtcgcc aactaatttt aagcttatat aagctactat
    14641 tggcaaaaac actatacaaa tagcaagttg aataaatgct gatactgcaa ctccccacat
    14701 tcctgatgta taagtatata taatgataac tataactcct ataattacag ctatatcata
    14761 aggaatacca aatgcagtag atacagaacc aaaagaaatc aattgactac ccataatagc
    14821 tagtatagat attggtgtta caagactttg ataagctctt aaaaatacac tatgaccata
    14881 tctagtttca atataatcag caggtgttat atcacaagat aagcttctta attttcctgc
    14941 gaaaaatgca tttataaagc aagctaaagc tgcacctata gtagaataca ttccaaccca
    15001 aagtcctctt tcagctcccc attgaactcc accaactaag caccctcctc caaaagatgt
    15061 agcagcaatg gttgcagcta gtataggcaa aggcagattt ctacctgcga ttaggaaatc
    15121 ggatgctgtt ttaacttttt ttgaaaaata aaaaccaatc catatgtata ttgcacacgt
    15181 aacaattaaa agtaacatag tcttttctcc tttataaaat attttaataa aatatacaaa
    15241 atatatttaa aatatatttt atataaaagt agtacgatat ttgttttatt ggttttagat
    15301 taatatagct ataataattt atgatattag atggaaatta cgtaaaaata gaaaattgaa
    15361 aattctgaaa tttttgcata ttgatattta tctcatagat tcttttttgt aattgtaaca
    15421 cgcttttatt tttaaatcaa tagtacatgt ataaaaataa aaggaattta aataagaaaa
    15481 agatattttt aatatctgga tgtagtatag aaatatcttg aataaattat tcttgaataa
    15541 aattataaaa aattaaaatc actagaaata tgataaaata atttaaaata cgcatttcaa
    15601 tgacatttca aaacaagaaa ataataaaaa acaaacctaa attaagtcta aatagctttt
    15661 tagttaattt tagtagtaaa aaataaaact taaaaagtgt ttgacaatta tgaattttga
    15721 gaatataatt aaattaaaat tatacacata taaaaatata ctcctgaatc aagaatgaga
    15781 tatttaagat tcaaaatata tattattata cgtgaataat aaaaagtaag taaattttat
    15841 aagggagggg tagatgtgag tagtcaagaa agcaaaccaa aaggaaatct tatatcaaat
    15901 tttagagatg atatgagaga ccctaagaaa agagcaatat acacatattc aagttctata
    15961 aatttagcgt acaattttat aggttacttt gtatcaactg ttacaaatat ttttttaact
    16021 gatgtggcaa aacttggtgt aattatggca ggtggtatgc aaattataca atctttcata
    16081 aaaattgctg tagctcctat aacaggtaca gtatttgaca aacaaccatt caaaaaagga
    16141 aagtattatc catggcttag atatgcacca gcagcgttag cattaacata tggaatattt
    16201 ttcatagttc cattaatgaa aataagtcca gcattacttt tacctttgat gacagcttta
    16261 ttattaatag catcttgtgc tcagcaagta gttttcacta taatttatgc tatttaccct
    16321 gtagttgcta agacacctag agaccgagtt ataggctcaa ctactacgaa tatatttaaa
    16381 gaagttggta aattcttagt aggtttttca tatccgttat tattagtttt atttgcagat
    16441 gtattaggtg gagaaggaat gggttattta ggtacctact tattctttgc agcaggatgc
    16501 cttttagtat tttggttttc ttcaacagag ataataaaat ctggagcaga agaagaagtt
    16561 cttcaaaaag aagagaagcc aaagattaaa gcaagtgaaa tggcaaaagc tttattcact
    16621 aatgtaccac ttatgatggc attttgttta gaatttctta tatgtataag atctatagga
    16681 ttaggacctt tggctccata ttattttaaa tatgtaatag aagatgaacg tggattagca
    16741 gtatttttat caatcatgcc tttggtaagt gtagcattca tgtttttcgc accagtgttt
    16801 ataaaaatct gtagagagca aaaactagct tcaataattt ctttttctat atgtgcacta
    16861 tgccacttat tggttgcatg gactccttgg gggaaaacta ctttaggagt aactatgttg
    16921 ttggcaattg gtggaggttt ttcaaatgta gtatcaataa taaatcttaa tttctttgcc
    16981 ggttcttgtg attatgggca ttggaaatca ggaaaagact tacctggctt aagtatgtca
    17041 ctatatccag ttgcaataca agtaggagta ttacttgcaa ctactataag aacagtttta
    17101 atgaactcaa tgggatatca agctgatatg gtagtcacag aagcagttaa atcaggtttt
    17161 ataaatatga tttcttattc tatggcaata cctttaataa tagctgttgt tatagcaata
    17221 ctatatccag taagtgacaa gaaattaaac caaataagag aagagttaaa tcaaagaaat
    17281 gcttagttaa aagaaagttg agtagatggt taatttaagc tattaaagta agtagacgca
    17341 atagcgttta tataaatgaa aatacatata cagagggggc ttttaaaaat gatagaaaaa
    17401 ttattgagaa ataccgtaaa agaattacat caatatgttc caggtgaacc aatagaaaaa
    17461 gttaaggaaa aatatggtgt aaaagaaata ataaaattag cttcaaatga aaatcctcta
    17521 ggaccatcac caaaagcaat agaagctatg attgaaatgt taaaacaagg tcaactttat
    17581 ccagagccag aagctaacga acttagaaga aaattagctg aaaagctaga tttaaaacca
    17641 gaaaatttta ttgttgctaa tggtgcagat aacgttatca ctctaatagg tgaggctttt
    17701 ataaatagag gagatgaagt tatatattgt aacccaacat ttccatcata tagaactgca
    17761 actataaaaa atgaagggat accagtagaa gtacctttaa cagaagatta taagtatgat
    17821 ttacaaggta tattagataa gattacagat aaaacaaaat taatatgtgt atgtaaccct
    17881 aataatccaa caggaacaat tgtggatgat aaagagttag aagaattttt aaagaaagtc
    17941 cctgaaaata ttataactat attggatgaa gcatatatag aatttttaac agttcctaat
    18001 tatgtggatg gacttaagta tgtaagggaa aattataacg ttatagtaac aagaactttc
    18061 tctaaaatat atggtcttgc agggcttaga gtaggatatg gtattgctaa agatgagata
    18121 ataagaactt tatttacagt aaaagagcct ttctctgcaa atcgtgttgc tataagtgga
    18181 gcaacagcag cacttgatga tgaagagttt ataaaagaaa catatgaatt aaatagagtt
    18241 ggaatggctt actttaaaga agagtttaca aaaatgggat ttgatgttgt agattcacaa
    18301 tcaaatttcc tttatgtaga tatgaaaaca gatataccta agttatttga agacttgaaa
    18361 aaaagagggt ttgtaataag accaagtgct acacatgcac gtgtaagtat tggaactatg
    18421 gaagaaaata ggaaatttgt agcagtttta aaggaaatat taaatattaa aggagagcca
    18481 agtattggat aatagataga aatattatga aacggggtgt agatatgaac ttaaaaataa
    18541 acgcagagag atgtaaaagt tgtgaatact gcgttatatc ttgtaaaaaa ggagcattaa
    18601 aaatatcaag taagataaat aaagaaggtt atgctcatgt agaagttgat gagagtaaat
    18661 gcatactttg tggaatttgc tatcaggtgt gtccagataa tgtttttgaa ataattaaag
    18721 aagaagcatg tcaagaggct tagaaggagt tgggataata tgaaaaagat gtggaagggg
    18781 aaccacgcca ttgcagaagc agccctaaga ggaggttgtg aattttatgc aggatatcca
    18841 attacaccac aaacagaggt aatggaattt ttatcacata gaatgtctga acttggaaga
    18901 acttttatac agtccgaaaa tgagatggct gctatatata tggtatatgg agcatatgca
    18961 agtggaatga ggtctatgac gagttcttca ggaccaggaa tatctttaaa acaagaaggg
    19021 atttcttact tatgtgcaaa tcattaccct tgtgtaatcg taaatgtaca gagatggggg
    19081 cctggtcttg gctcattgga ctcagcacag acagactatc taagagatac tagaggggga
    19141 ggaaatggag attatcattt gatagtttat gcaccaaaca gtattcaaga gactgtagat
    19201 ttgatgtata actcatttga tgtagcggag aagtacagag tgcctgtcga aattttgaca
    19261 gaagcagctt taggtcaaat gatggaacca gtagaatttc cagagtttaa gaagagagaa
    19321 ggagatttag gttggactta tgatggaagt aatagagacc atgcaaaggt tgcagataac
    19381 caaaagccaa ctttttgtat ggagaaacgt atgagaataa ctgaaaatga acaacaatgg
    19441 gaagattatc aagtagaaga tgcagaatat gtgtttgtag cgtttggtat accatcaaga
    19501 acaactatga atgctgttag aagacttaga gaacaaggtg aaaaagttgg aataataaga
    19561 ccaataacag tatggccttt cccatataaa gcatttgaaa aggtaagtaa agatgtaaaa
    19621 ggatttatct cagtagaatc aacagacaca ggtcaattag tagaagatgt tgctttagcc
    19681 tcaaagaaag tatgtaaaga aaatgtacct gtgtatggtt tatttagtgg aaatcatata
    19741 ccaaaaacat tgcaagtaat ggacacttat agcaaaataa aatctggcga aatcaaggag
    19801 gtgttctaat atggctacag aaaaattaac acctagcgtt gtttcaatac caaacaagtt
    19861 ttgcccaggt tgtggtcatg gaatagtaaa tcgtataata gcagaggtaa tagaagaaca
    19921 tggatatgaa aaaaatcatg tattaacatt aggagttggt tgtgtctgca atatgaattt
    19981 tagctggaat ggtgataaga tgcaaactgc acatggtaga gcttcatcta cagctatagg
    20041 agttaaagta gcacttccag atacattagt aatgacttac caaggtgatg gagatgctta
    20101 tgttataggt ctttctgaaa ctttaaatac agcatataga aatcataatg tgactgtatt
    20161 tgtaataaac aataataatt ttgcaatgac tggtggacaa atgtcatgga ccactatgcc
    20221 gggtcaagtc acaacaacaa gtgtaaatgg aagagatata aagactactg gtagtccact
    20281 gaaagttcct gagatggtgg caaacttctt tgatgtagca tatgtagcaa gaggttcagt
    20341 tcatagccca aaggaaataa ttaatctaaa aaaatatata aaaaatgcaa tagaagctca
    20401 attaaatgga gagggatatt ccttagttga aatattagca ccttgcccaa ctaactgggg
    20461 tgtatcacta gagaaatcta tcaaatggat ggaagaagaa atagtgccat attatgctct
    20521 tggcgaattt aagcaaaggg atggtgaata gttatggaaa aagagctagt atttgcaggg
    20581 tttggtggtc aaggagtttt aactcttggt ctgattgtag ctgagtcagc acttgaattg
    20641 gggaaacaag taacttggat gcctgcatat ggtccaacta tgagaggtgg aaaagcctat
    20701 agtgtagtaa agttttctga tgagagtata ggtgggcctg atatggaaga aatagatgtt
    20761 ttagtagcaa tgaataaacc atctttagat tatataaatt tagttaaaga aggtggaaca
    20821 gtagttatta atacatctgc aatagatgag aatgtaacat taagagaaga tataagtgta
    20881 gttaaaataa attgtcagga attagctcaa aaagtaaaca atccaaaagc agcaaatata
    20941 gtagtacttg gagcattaat tgctaaaact gggttatttg aaaaagaatt agctttaaaa
    21001 actatgtgtg atttctttga ggaaaaagga aaaggaaagt ttaatgttca aaatgaagca
    21061 gcattcatgg aaggctataa taacgccatt tgataaatta cccttatctt aagtgattta
    21121 tctcaagatt taataatctt tagtgccaag agaaacttca tcttgagata aaattcactt
    21181 aaaatcacaa ctataaacat ataggagcgt gaatttatga gtttggaaaa acttattaga
    21241 ccaaaaagta ttgctatagt aggagtgact gataaacttg gttttggaag aagtgcagca
    21301 cttagtatag taaaaagtaa ggaaacagat agagtatatt atgttaatcc caaaagagaa
    21361 gaattgtttg ggagaaaatg ttataagacg atacaagaag ttccagaagt agtagactgt
    21421 gtagtagtat gtacgcctag aaatgtagtt ccatctgtat taaaagattc tggagagtta
    21481 ggaacaaagg cagcagtggt atatgctagt ggatttgcag aggaaggtac agaggaaggt
    21541 acagatttag aaaatcaact tatagaaata tcaaatacat acgatatgaa aatattgggt
    21601 ccaaactgca tggggttgct aaattgtata gataaggtta atctatgggc aggaggttct
    21661 aaatgggatt tagatactaa aaaacctggt ataggaattg taggtcaaag tggatttata
    21721 actgctgaaa ttgtttcaag tgattatttt aatatatctt atggtttttc aacaggaaat
    21781 ggaaatatag ttacactaga agatgcagta gatttccttg tagatgatga ttatgcatca
    21841 gtaatagcaa tttaccttga aggtttaaaa aatcctcaaa aatttataga tgctttaaaa
    21901 agggcagcac aaaaaagaaa gccagtaata atattgaaat caggaaggtc agaaaaaggt
    21961 gctatttctg ctgcttctca tacaggaaat ttagctggtt cgagtaaagc ttttgaaagt
    22021 atttttgaaa aatatggagt aatttctgtg gaaaatttag aacagtttat gtgtttagca
    22081 caagctttta gtgttttaga tggtaattta cctgcaaatt ctaattttgc agcaataaac
    22141 ttctcaggag gagaaaatac tatttgtgca gatttagcag aagaaaatgg tgtagaactt
    22201 gcagaaatat cttctgaaac taaagaagaa atggaaaaat atcttccagg atttgcaaca
    22261 cctaaaaatc cactagatgc tacaacagca ttattccatg aaaaggatat gatagtaggt
    22321 ttattacata cctttgaaaa ggatgatagt gttggattta ctatggtagg tgcaaatata
    22381 agagatgaag aaaatgaaat gcatgaaacc ctttgtaaag ctgtaagtga agctagagaa
    22441 caaggattga aaaaacctgt gtttgcagtt cctacacttg aaggaaatag atatttagat
    22501 tataggacta gattagaaga taatcaagtg cctataatgt catcagttgg aactacattt
    22561 acttgtttta ataaaatggc taagtttata gattatgatt attcaaaaag aactttagaa
    22621 tttaaagctg ttaagaaaag agagtcaaat aatgtagtag cattatcaga attagatagt
    22681 aagattgaga tgaaaaaata tggagtacca gttccaggac aaggtaatgc aaaaagtatt
    22741 gatgaattag atgaaatctt aaaatatatt aagtatcctg ttgttttaaa aataaattct
    22801 tctgaaatat tgcacaaatc tgatgttgga ggagttaaaa taggaattaa gaatagagat
    22861 gaggcagtag atgcatataa tgagatttta actaatgtaa aaaaagcaaa accagatgct
    22921 aatattgatg gtatattagt tcaagaaatg gtagaaagtg gtatagaaat tattattggt
    22981 ataactaatg atgaccaatt tggaccaatg ttattagtcg gtttaggagg agtatttgta
    23041 gaggtattta aagatactac attatatcca ttacctataa atcatgatga agctattatg
    23101 atgcttaaaa aactaaaatc atttaagctt ttaaatggct atagaggaag tgagccatgt
    23161 gatattgatg ctcttgcaga tatgatggtc aagttaggaa aatatgctta tgaaaataag
    23221 gatgaagtca aggaaataga cttaaatcca gtgtttgtat atcctaaagg aaaaggcgta
    23281 tgtgcagtag atgccttaat agttaaatat aaatagttta taagttttgg tattcaacca
    23341 taattaaagc accaactgaa aatcacattt tgtaagttag atagtgtgat tttcagtcac
    23401 cccaaattta atttaaaaat attttaaaat gaaagtatag ttttaagttt cattgtgaaa
    23461 tagcactgta taaacaataa aatactacgt ataaaacgaa taataaaagg tgttttaatg
    23521 ataagaatca atcttgattt tcattaaaac accttcttta ttatattaaa aatttttaaa
    23581 cgttatattg tcacaggtgg gtttgttgga gctgcatatg tacgattagc aaattcttgg
    23641 tcaacaaaga atagcccacc ctctccagca agtttaacac gttttatatt gtcttcacaa
    23701 tttgtttctt cttctgcttg ttcagatata aaccaaagta agaattgaga agttctaaag
    23761 tctgattcag agtttgctac agctgctaag ttgtttatta aagctgtaac ctttttttca
    23821 tgagctaacg tacgctcaag aatatccatt gcagaagtaa agtctgaatc tggcattggg
    23881 atagcatcaa gctgaacctt tcctcctaca ttatgtaagt atttgtaaaa aaacatagcg
    23941 tggtctgtct cttctttata ttgaacataa aaccaattag aaaatccttt aagtccttct
    24001 gcttcaaggt aagaagacat agaaagataa agatacgcag aatataattc atggttaatc
    24061 tgctcattaa gtaatttttc cattttagct gaaatcattt ttatacctcc aaattttaaa
    24121 tgctcttata aaatataata atattaaatg gaaaaatatt caataaaagt gtttaaatat
    24181 tttacatatt taataaaaat ttatactacc attaaaaaaa ttataactta caatggctat
    24241 agagccaatt aatggtgcat ttgctccaaa atttgaatgc cttacactta tttttttata
    24301 tttagaaaaa cttgctgaag cagtcaattt ttttaataat gtattttcta taaatgtacc
    24361 aggtatatta aagtcatagc ctattattat agaactacaa tcaatcaatg taagtgtatt
    24421 aactaatgca tatgatacgt atgtacaaaa ttcatcaagc aaaaacatgg caagactatc
    24481 tttattattt gcctcatcta ttaacttgac taaagaaaaa tctttacagt taattaatgg
    24541 ggagttagga taaatatggc tcaatgattc aattctttta attagattac tgacacttgt
    24601 ataataatct aaacatccat tgttaccaca actgcacaat ggtccactaa aattaattga
    24661 tgtatgtcct atttctccac tttgtcctag gttgccagta tgaagtttat tttctagaac
    24721 tagaccagct ccaataccat tcattatgtg taggtatata taatttgata tatttttacc
    24781 taaaccatac attttttctg ctaatgcacc cgaattagca tcatttatca aaaatattgg
    24841 caaatcagac atttctttta taaaatctac tatatttagg tttgatacat ttccaaaatc
    24901 tgggggattt agtatggtac catttatatc atctactgga cctattgaag aaataccaat
    24961 tccaattata tctctcttgt tgattttcat tattttagta aacattcttt ttattatatc
    25021 ttttaaaaca tcatttgata gaaatttagg gtaagtttca gaaagttgtt ttacaatatt
    25081 accttttaaa tctgaaataa ttaccttaca tatatttctt cttattagga ttccacaaat
    25141 acaaggcgat atattagaaa tatctaataa aataggttta cgacctgatg aatgtgcatt
    25201 taaagttgat gactctattt ccctaatcat attttcatta ataagttcag taactagatt
    25261 tgataaagtc attttagtaa gtcctgtaga cttagctaaa tcaactctgg acataggtgt
    25321 atttgtagaa agtaatttca atattattaa cttattttta atttttacat ctttgatgtt
    25381 agaaccttgt ttgttactca tcataaatct ccttaaataa agttaagtgt tttatttatt
    25441 ttcaagtata ctatcacctt ataatagagt aacatttttt tacttgaaaa tatcattaat
    25501 tagaatatat cacattatat atcataaaac atataaaaaa atattagaat taaattaaaa
    25561 gtgaaaagta gattgatata taaatagtaa atacttaatt aaaaaaagat aatgatagca
    25621 ataattattg ttaccaagaa tctactactt caagtgttac cttaggtatt taagttgata
    25681 gtggtttgca cgtaataaac ttgatgtaat atatattctt aataatatcg ataaaagatt
    25741 tacttaaaaa taatatagat tatgtaaaca tataatctat ttattgtata caataaaatt
    25801 tcattttgta aaacagtgaa ttaaatatgt aatatagata tcgattttta ttacaaattg
    25861 ttactaaata taggtacatt agaacaaaaa tctagtaaat tgtaactaaa atgtaaattt
    25921 ttcctttaat ctatacaata ttatggaaac tttttgtaat ttatgatata ataacaaata
    25981 tataattatt aaattataat aaatgactat agcgtagatg taatactatg ttatagtcat
    26041 ttttgaatta aacttgatat atcaaggggg aagaatatga gaacaattag aagagtttta
    26101 gcattaggtt taacattagc tatatttcta ataaatgtac ctaatgtaga tgcattaaca
    26161 tcagatacaa ttaaaggtaa caatatatat gagacggctg gattaatagc agataaaaag
    26221 agttatgata cagcaattat ggtaaatatg gataattcta tagcagatgg tctttcagca
    26281 agtggtcttg caggtgctgt tgatgctcca attttgcttg cacaaaaaaa taagatacca
    26341 aatgaaacaa aacaaagatt aaaaaatgtt aaaaagatat acataatagg taaagaatta
    26401 tcaataagta agtcagtaga aactgaacta aaaaacacag gggcacaggt aactagattg
    26461 ggtggagatg acagaataaa gactagttat agtgttgcta aagaggtaaa tggtatcaaa
    26521 aaagttgatg aagtgatatt aactaatgca tataaaggag aagcagatac aataagtgct
    26581 gcacccgtat cagtaagaga tatagctcct atagtactta cagatggaaa gagtgtgcct
    26641 ttttcaacaa gcaatgtaaa aacatatgca gtaggtggga gtatatcaat gagcactagt
    26701 ttagttaata aaactaatgc taaaagactt ggtggttcag atagatatga tacaaataag
    26761 aaagttataa aagagtttta tccagatgca tcagaatttt atttgagtga tggatatgat
    26821 ttagtaaatg cacttacagg ttctacaatt gctaaggaaa atccaattgt attggtgtca
    26881 gaaagtagtg ataagtctat attagcagga gcagataaga ttactagatt aggttcaata
    26941 agtgacagtg tgtataataa gtgtgtttct gctgcacaaa ataatggcga ttcgtctaca
    27001 aaaggtgagt cacctatgaa aaatgagaca agcatattag gtcagccaac agctagttta
    27061 gaagcgtgct taaaatgggc aaaatctaaa aaagctaatg atttatttat agagttaata
    27121 ccaatattat atgatactgc tgttcaggaa ggtgttaatc ctgttttggc agtagctcaa
    27181 tctgcaaaag aaactggttt ttgtaatttt ggtggagtat tagatgcatc atttaagaat
    27241 ccttgtggac ttaaaacttc tgtaggtggt tctgatactg ataagaatgc ccattcaaga
    27301 tttgatactt gggaagaagg aatattagct caaattcaac atttatgctt atatgcagga
    27361 caagatggtt acccactttc aaatccagta gaccctagac atgaaaaatc tttatttggt
    27421 aaggctaaaa cagttgaaag tttatctaat aattgggctg gaggtcaata tggacaagat
    27481 ttagtaagaa tgatgggaga aattgaggca acaaaataat tgaagattat caaatatcca
    27541 ataaataagg attgattatt atgaaaaaga gtaatatttt tagtatcata tttcctacag
    27601 tcataatggt gctaatgttt ttaacttttg ctacagatat atttaatatt ccagatattc
    27661 aatctaaaag tatttttgtt gtgggaatgg ttttgatttt tccaatttct tttttgatac
    27721 aagggataat ttgtgtatta aataagacta attggatttt atctcttatt gtttctttag
    27781 taacttatat agtattaatg tatatatttt taaatgattc tgcatatata tatgttttac
    27841 tttatacagc tttttatatg attggacata taacagctaa actctattac aaaattaaga
    27901 cttttaaaaa ttaaattgaa gtatataaaa gtaacattag gagaagtatc cttaatgatt
    27961 ttctaaaatc agaaataggt gcttctcttt tttgtaaaaa taaaagtatg taaataaaat
    28021 ttaaccatta taattttctt ttaacaaatg tatacaataa acttgttgta taattaagat
    28081 agataaaata aagggaggga taatatgaat ttaatagata atcatattca tactaatttt
    28141 tcaagtgatg gaaaggattc catggaagat acaataaaaa aagctataag tattggtgtt
    28201 agatatttga cttttacaga ccatttagaa catgatgaag atagaggatt ttgcataaat
    28261 tataatgact atgttccagt atttaataag tttaaagaaa aatataaaaa ggacatagag
    28321 ttattactag gtgttgaagt gggttacaga aaacatctaa aaaatgaaat agaagaaata
    28381 ataaattcta atccttttga ttttgtattg tgctcaactc atacaattga caatgtacct
    28441 gttccatcaa aggcgtattt taaaggtctt agcaaagaag atgcgtatta taaatatttt
    28501 aatagcatac ttgaaactaa tcgtgaattt ggagattaca atatatatgg tcatttggat
    28561 tatatatcta ggtatggaat atattcagat aatagagtta tatacaatga ctttaaagat
    28621 gttattgatg aggtcttaaa gtcaataatc aataatggga gtggtataga gctaaatact
    28681 tctggttata gatatggact aaatgctata catccaaatg aagatattct aaaaagatat
    28741 aaagaacttg gaggatttat agttactgta ggttctgatt ctcatagggt agaagatata
    28801 tgcaaagatt ttgatgtggc ctatgatatg cttaagtatc ttgactttaa atatgtatct
    28861 ttatttaaag aaagagaaac ctattttgta aatatagaaa aagttaaatc taacaatata
    28921 gcttagagtg tgttttgaag taaattaata gatagttaaa aagttaatag ttatagtatt
    28981 gtatcctcta gaaaaatact agaggttttt attttgctaa aataactaaa tagaattaaa
    29041 tttaaatagt atagcttatt ttaaattgaa tagtttattg ttgatatatt ttactattat
    29101 atatttttat tgtgatataa tagtaaaata tattaaccta tctttagatt atataaatta
    29161 ttataaagga gggaaatttt aaaatgtcta ataaaaataa agaaaatata actttaagta
    29221 atcaaatcaa aggaacaatt caaaatagtt taacaaaaga agctatatta catataccaa
    29281 tgagcaatta tgcctatggt tatgatagag aaacactaca tataagactt agaactaaaa
    29341 aaaatgaagc gaaaagagta attttacgaa taggagacca atatgtgtgg gataaaggag
    29401 gtgcaggagg aggaaattta aatgcatctg gagttggttg gtctggtgga acaaatatag
    29461 taatgagtaa agaagtagaa actgaattat ttgactattg gatagctaag tgtaagcctt
    29521 taaataaacg ctcacgatat ggctttataa tagaaggtca agaggaaaaa cttttattta
    29581 cagaaaaaag aataatagag ttgggaaatg aaaatgatga aaaggaatta tgtgaaatag
    29641 gtaatttttt tggatatcca tatttaaatt atatagatat acctaaagtg ccaaattggg
    29701 tgaaagatac tgtttggtat cagatatttc cagatagatt tgcaaatggt gacccgtcta
    29761 taaacccaga aggagtagat aaatggggag ctattccaac cagagataat tttacaggtg
    29821 gagatttaca aggtgtgata gaacacttag attatttgag tgatttggga ataaacggaa
    29881 tttacttttg ccctattaca attggaaaaa ccaatcatag atatgatacg gtagattata
    29941 tggaggtaga ccctacatta ggagataaag agactttaaa aaaactaata gaagaagcgc
    30001 ataagagaaa tataaaaata atgttggatg ctgtttttaa tcatatagga tattattcta
    30061 aacagtggca agatgtagtt caaaataagg aaaattctcg atataaaaac tggttttata
    30121 taaaagatat gagtaaaatt gatactccaa tagaacaaat agatgaaaaa aatatacctt
    30181 atgaaacctt tgggtgtgaa aaatatatgc ctaaacttaa tacagaaaat tcagaagtaa
    30241 taaaatattt attggatgta ggcaagtact ggatacagga atttgatata gatgcgtgga
    30301 gattagatgt ttcaaatgaa gtagaccatg ttttttggag aaagtttaga gaagaagtca
    30361 aaaaagtaaa accagacatt tatatattgg gagaaatttg gcatggtagt ttaccatggt
    30421 taatgggtga ccaatttgat tcagttatga attacttgat gtcagaagcc atgaaaaaat
    30481 tcttttgtac agatgagata aacgccgaag aatttaagta tatgataaat gatgtaatgg
    30541 taagttatcc aatacaagtt agtgaagtta tttttaattt acttggaagt cacgatacta
    30601 caagaatatt gacttatgct aatggaaata ttgatagatt taaacttgca tatatgttta
    30661 tgtttgtaca aacaggatgt ccttgtatat actatggtga tgaaatcgga atggaaggag
    30721 aattaagttc aatatctgaa ggtcaaagaa aatgtatgga atggaatgaa gaaaaatgga
    30781 ataaggatat atttgatttt atgaagaaga ttattagact tcgtaaagaa aataaagaac
    30841 ttaggtctat atcaaatgaa tgggtgttag cagataagga aaatggaacg attatattga
    30901 aaaaagaatc tatttctata ataataaata attcatctaa aaatataatt ttgacgttac
    30961 cagattattt agcaaataaa aaagtaaaag atttatatga agaagaaata gttgatttaa
    31021 aagaagaact aatgttagag aaatacaagt tcattatttt aaaataatac aaaaaagtat
    31081 ttattttaga tttcatgtta aattattata cagtttaaac aagtctttat aaacgataaa
    31141 aaatatggtc tacaagtgag tgaattgaaa gtagatttta aattaaagac tgagttagag
    31201 tagataattt tataaataat atcttaaata caagatagaa aataaattga ttattagtct
    31261 aaaaatttct tgtagaaaga ggaaataaga atgattgaag catttatatt tgatttagat
    31321 ggtgtaatta cagatactgc atattatcac tatatggctt ggagaaaact agctcataaa
    31381 gttgggatag atatagacac aaaatttaat gaatctttaa aaggcataag tagaatggag
    31441 tcattggaca ggatattaga atttggaaat aagaaatatt cattttcaga agaagaaaaa
    31501 gtgagaatgg ctgaagaaaa aaataattac tatgtatcat tgatagatga gataacttca
    31561 aatgatattt tgccaggcat agaaagcttg ttaattgatg taaaatctaa taatataaag
    31621 ataggtctat cttctgcaag taagaatgca ataaatgtat taaatcattt gggtataagt
    31681 gacaaatttg attttatagc tgatgcagga aaatgtaaaa acaataaacc acatccagag
    31741 atatttctta tgtcagcgaa agggcttaat gtaaatccac aaaattgcat agggatagag
    31801 gatgcaagtg caggtataga cgctataaac tcagctaata tgttttctgt tggtgttgga
    31861 aattatgaaa acttaaaaaa agcaaattta gttgtagatt caacaaatca attaaagttt
    31921 gaatatatac aagaaaagta taatgagtat atagttagga gaattatatg aaatgtttat
    31981 ttagtaatgt agatgagtgg aagattatac aagataagat tgaaatcaaa gaaaatagat
    32041 tagcagagtc cataatgagt ataggcaatg gatatatggg tatgagagga aactatgagg
    32101 aaaattatag tggagataca cacaaggggt cttatatagc tggagtatgg tttccagata
    32161 aaactcgtgt tggttggtgg aaaaatgggt atccagaata ctttggtaaa attcctaatt
    32221 cagtcaacta tataggtgta agaattttca tagatgatgt agaattagat ttagcaaaat
    32281 gtaaagtaga agattttcat agagaattag atatgaaaaa tggtatttta aatcgtaggt
    32341 ttattgtaaa tataaatgat aaaaaatttg aagttagggt tactaggttt ttaagtatat
    32401 ctgttaagga acttgcagta attaaataca gtataaaatc attaaattct aatactaaaa
    32461 taaaatttgt accatattta gattcaaata taaaaaatga agattcaaac tatgaggaaa
    32521 agttttggaa tggaatttct tcaagttctt tagaatataa agggagtatt ctttctcgaa
    32581 caaaggagaa tgcatttaat acaccagtat tcactgtggg ttcaatgatg tatattaaga
    32641 caaatggtga tgtagaagct gtatctcatg agagtgatta taattactgt gaaaattcga
    32701 taacaatgga tgttttaaaa aatgaggttg caagtataga aaaatatgta tctataacct
    32761 caactagaga ttataaggaa agtgagctat taagaaaatg tgaagacatt ttaaatagag
    32821 aactatctaa aagttatgat gatatattaa atgaacatat aaagttatgg aataaaagat
    32881 gggaaagtgc agatgtaaaa ataaatggag ataaaagtag ccaacaaggt ataagatata
    32941 atttattcca actattttca acatattatg gagaagattc gcgattaaat ataggtccaa
    33001 aaggatttac tggtgaaaag tatggaggag ctacttattg ggatacagaa gcgttttgtg
    33061 ttccagtata tctaggtgta gcagataagg aggtaactag aaatctttta gaatataggt
    33121 acaatcagtt agaacaggca aaggataatg caaaaaaact aggtcttaaa ggtgctttat
    33181 atccaatggt aacatttgat ggagtagaat gtcataatga atgggagata acatttgagg
    33241 aaatccaccg aaatggaagt atagtatatg caatatataa ctatacaaat tatacaggtg
    33301 actataaata tataaaagaa aaaggaatag atgtaataat agaaatagct agattttggg
    33361 caagtagagt tcatttgtct acaaaaaaag atttgtatat gatacatgga gtaacaggtc
    33421 caaacgagta tgaaaacaat atcaataata attggtatac taattatata gctaaatggt
    33481 gtttagatta tgctgtagaa aatatcttac gattagagaa agagtgtaat gaatgtattg
    33541 acagaaataa tgtgactagg gaagaagttg agttttggaa aataatatca aataaaatgt
    33601 atctgctgta tgatgaggaa ctacaaataa taattcaaaa tgataatttt ttagataaag
    33661 aatttgtaga agtaaaggat ttaccaaaag aaaattttcc tcttaatcaa aattggtctt
    33721 gggataagat tcttaggtcg tgttttataa aacaagcaga tgtattacag ggaatttact
    33781 attttggaaa tagatttact aaagaagaaa aaaagagaaa ttttgacttc tatgaaaaat
    33841 atactgtaca tgaatcttct ttatcttcta gtatttattc tattattgcc tcagaaatag
    33901 ataacctaga aaaggcttat gaattatatt caagaacagc taggcttgat ttagataatt
    33961 acaataatga tacaaatgat ggactgcaca taacttcaat gtctggttca tggctttcca
    34021 ttgtacatgg atttgcaggc atgagaacat ggaatgaaac tctatctttt gaccctaagt
    34081 tgccaaaaga gtggaaaaat tattctttca atataaatta tagagataat attattaatg
    34141 tagatgtatg tagtgattta attaaaatag aaaatttaaa aggtaaacca ataaaaatta
    34201 ttgtatatgg gaaaaaatat atattagaaa aatgtataaa aattgataaa tagatttaat
    34261 aatattttta ttatataaat agttaaaata agctatctaa ttatttattt attttaacta
    34321 ttttgtgtga tagaaaacta tatattataa caatagtagt gcttttaatt aaatatattt
    34381 cataaatctt cataaaattt tcaaaatttc gtaaagaata tgtcacaaaa gtaaggtata
    34441 ttatattcag cagatagtat aagggaggac aatatttatg aagaataaaa aattcattgt
    34501 tataatactg ataatatcaa ttttaatagg tgtattagtg aaggaatatt catctagaga
    34561 gataaaaaag gatgatataa atgtcagtaa gtatataaaa tatgctgatt tagcaagtaa
    34621 aaataatgca caagttaact ggaagtatgt agcttccatt gttgctgtgt taaataaaaa
    34681 taacttaaaa aacgttaagg attcacagat acaagaagta tcagatttat ttgttaagaa
    34741 tttttctaaa aataataaaa taaataagtt aagtgatatt ttggatgagt tagaatttag
    34801 taatagacaa aaaagattgg ttgataatta tatagacaat cttaaggatt atggtataaa
    34861 accagaaaga ttgaagtctg atacaaaata tatgaagttt attgatgaaa ttaaaacaga
    34921 agcaatacaa aattataagg attataaaat acttccatct ataactattg cacaagctat
    34981 aatagaatct agctggggca agtcaacttt ggcaaaacaa tataacaatc tatttggtat
    35041 aaaggctgac gcttattgga aaggcaagtc agtgacttta gaaacgaaag aacatttaga
    35101 tacaattata gatgataaat ttagaatata tgatgataaa aatgaatcta taaaagacca
    35161 tgcaaaattt ttagccacaa ataaaaggta taaaaacaat ggtgtatttg atgcaaaaac
    35221 gtatatatat caagctaaag cattagaaaa ggcaggttat agtactgcga aggatgaaaa
    35281 tggcaatagt atatatgcag ctcgtctaat agaattaatt caacagtata atcttcaatt
    35341 aatagacagt gaaattcaaa gtgaaatgta actttgatta aatttttatt gataaggcta
    35401 tgatttttaa aatcatagcc ttattttgac atgcttttac ttgtaattat taaatcgata
    35461 tcattatctt tcaaaattta ctttatactg taaatcaaat tatttaagtt aaaacttgga
    35521 attatttata aaaggattat ttactttatc taaattctgc acttaaa
//
LOCUS       DAYAKB010000036        34134 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.036, whole genome shotgun sequence.
ACCESSION   DAYAKB010000036 DAYAKB010000000
VERSION     DAYAKB010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34134
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.036"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            105..806
                     /locus_tag="ACGI3L_002097"
     CDS             105..806
                     /locus_tag="ACGI3L_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFG9197806.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            888..1496
                     /locus_tag="ACGI3L_002098"
     CDS             888..1496
                     /locus_tag="ACGI3L_002098"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9197807.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            1820..2284
                     /locus_tag="ACGI3L_002099"
     CDS             1820..2284
                     /locus_tag="ACGI3L_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HFG9197808.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTYETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            2921..3937
                     /gene="gap"
                     /locus_tag="ACGI3L_002100"
     CDS             2921..3937
                     /gene="gap"
                     /locus_tag="ACGI3L_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFG9197809.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            4332..5501
                     /locus_tag="ACGI3L_002101"
     CDS             4332..5501
                     /locus_tag="ACGI3L_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197810.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYSPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            5881..10134
                     /locus_tag="ACGI3L_002102"
     CDS             5881..10134
                     /locus_tag="ACGI3L_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase-related protein"
                     /protein_id="HFG9197811.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            10283..10777
                     /locus_tag="ACGI3L_002103"
     CDS             10283..10777
                     /locus_tag="ACGI3L_002103"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFG9197812.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            10893..11270
                     /locus_tag="ACGI3L_002104"
     CDS             10893..11270
                     /locus_tag="ACGI3L_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HFG9197813.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            11476..11916
                     /locus_tag="ACGI3L_002105"
     CDS             11476..11916
                     /locus_tag="ACGI3L_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HFG9197814.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            12561..13868
                     /locus_tag="ACGI3L_002106"
     CDS             12561..13868
                     /locus_tag="ACGI3L_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197815.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    13954..14216
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14342..15145
                     /locus_tag="ACGI3L_002107"
     CDS             14342..15145
                     /locus_tag="ACGI3L_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9197816.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            15183..15794
                     /locus_tag="ACGI3L_002108"
     CDS             15183..15794
                     /locus_tag="ACGI3L_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFG9197817.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            15826..16497
                     /locus_tag="ACGI3L_002109"
     CDS             15826..16497
                     /locus_tag="ACGI3L_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFG9197818.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            16796..17158
                     /locus_tag="ACGI3L_002110"
     CDS             16796..17158
                     /locus_tag="ACGI3L_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFG9197819.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            17594..18295
                     /locus_tag="ACGI3L_002111"
     CDS             17594..18295
                     /locus_tag="ACGI3L_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HFG9197820.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDELCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            18566..19384
                     /gene="larE"
                     /locus_tag="ACGI3L_002112"
     CDS             18566..19384
                     /gene="larE"
                     /locus_tag="ACGI3L_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HFG9197821.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            19439..20587
                     /locus_tag="ACGI3L_002113"
     CDS             19439..20587
                     /locus_tag="ACGI3L_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFG9197822.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            20723..22111
                     /locus_tag="ACGI3L_002114"
     CDS             20723..22111
                     /locus_tag="ACGI3L_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9197823.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            22140..22838
                     /gene="walR"
                     /locus_tag="ACGI3L_002115"
     CDS             22140..22838
                     /gene="walR"
                     /locus_tag="ACGI3L_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism DNA-binding response
                     regulator WalR"
                     /protein_id="HFG9197824.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            22841..24274
                     /gene="walK"
                     /locus_tag="ACGI3L_002116"
     CDS             22841..24274
                     /gene="walK"
                     /locus_tag="ACGI3L_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFG9197825.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            24296..25033
                     /gene="truA"
                     /locus_tag="ACGI3L_002117"
     CDS             24296..25033
                     /gene="truA"
                     /locus_tag="ACGI3L_002117"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFG9197826.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHSPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    25144..25351
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25604..26803
                     /locus_tag="ACGI3L_002118"
     CDS             25604..26803
                     /locus_tag="ACGI3L_002118"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HFG9197827.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            27050..28096
                     /locus_tag="ACGI3L_002119"
     CDS             27050..28096
                     /locus_tag="ACGI3L_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtrH N-terminal domain-containing protein"
                     /protein_id="HFG9197828.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTGQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            28204..29367
                     /locus_tag="ACGI3L_002120"
     CDS             28204..29367
                     /locus_tag="ACGI3L_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9197829.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     NRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(29456..29836)
                     /locus_tag="ACGI3L_002121"
     CDS             complement(29456..29836)
                     /locus_tag="ACGI3L_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HFG9197830.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(29839..30498)
                     /locus_tag="ACGI3L_002122"
     CDS             complement(29839..30498)
                     /locus_tag="ACGI3L_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFG9197831.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(30604..31578)
                     /locus_tag="ACGI3L_002123"
     CDS             complement(30604..31578)
                     /locus_tag="ACGI3L_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFG9197832.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(31618..31965)
                     /locus_tag="ACGI3L_002124"
     CDS             complement(31618..31965)
                     /locus_tag="ACGI3L_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197833.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(32183..33139)
                     /locus_tag="ACGI3L_002125"
     CDS             complement(32183..33139)
                     /locus_tag="ACGI3L_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFG9197834.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            33584..33952
                     /locus_tag="ACGI3L_002126"
     CDS             33584..33952
                     /locus_tag="ACGI3L_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HFG9197835.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT        13684 a         3412 c         5778 g        11260 t
ORIGIN      
        1 tttaaaaaaa ttaaacaatt agcaaatagg gggtatattt ataagacaca aagtgataaa
       61 atctatttag aaaataatgt aaaataacag gaggataaag caaaatgaaa tttatagtag
      121 aaaaagaagt ttttgataaa ttagaaaatg tatgctttgg tgtagtagtt gcaaaaggaa
      181 tagataatac taaagaaata gaaagaataa gcaacctttt agatataagt atagatagag
      241 tagaagatta cttcaaagat aaaaaagtaa aggaatcaga agaaattata ccatatagag
      301 aggcatttag aagtctaggc atgaacccaa ataaatttat gagttcgata gaagcaatga
      361 caacaagggt tgctaagaat aagaaacttc ctcatataaa tcctattgta gatttaggaa
      421 actctatttc tttaaaatat ttacttccaa tgggtgctca tgatatggat tttagaaatg
      481 atgatgtata tgttagattt tctaaaaaag gggataaatt tgtaccattt ggagaaactg
      541 atgttgaatt aatggaagaa ggagaattaa tttattcagt tggagacatg gtaaaaacta
      601 gaagatggat atggagacaa ggagaggaag gaaaaattac taatagctca aaaaatatat
      661 tttttcctat agatggtttt actgatgcta atttagataa ggtaatgagt gcaagagaag
      721 aattagcaaa attgttaaag gaaatattta attgtgaaat taaagtaggt tttgtagata
      781 aagataatcc tgaaatggaa atataataag ttgttgaata cttgttaaga tattatattt
      841 acttaatgat gttaaaaagg tattaaaaaa gaaaggtcgt agtaaatttg aaaaaaacta
      901 taataaagaa tgtaaatcca atgattgaaa ataagtttat aggacttttt gaaatagagt
      961 ataaaaacaa attagatgaa gataaggttt ggatggtagc atcaagaaaa agtagtgagc
     1021 aattaaaaaa tatttatttg aagaatgaag aagatagtgt agatgcagtt gtaatagttg
     1081 ggcttcataa aagtagtaaa aaattaattt taataagaca atttagagta cctattaatg
     1141 gatatatata cgagttacca gcaggtcttg ttgatgaagg agagtctata gatatttccg
     1201 ttgaaagaga acttagagaa gaaacaggac ttactctttt agaaattaaa aaaaataaaa
     1261 gtattgataa agtttattta tctcctggaa tgagtgatga atctgttgcc tttgtttatt
     1321 gtatatgtga tggtgatata acagatgaat ttttagaacc agatgaagag attgaagcgc
     1381 ttttaatttc gcaagaagat gcaaaagaga ttttacaaag taatcataag atagacacaa
     1441 aagcattttt gattttacaa atgtttgtga gtttaggagc taaattattt gaatagatat
     1501 atagaaaaga ggttatatag aagagtaaaa taataaagtt tattttactt gtataaatta
     1561 taatctcttt ttttatacaa taaagtataa ttttgtgtat ttttaaataa gtgacttgac
     1621 tcttaaattt tcataatatg ttataaacca atttaagata ctacaataat taaaattcca
     1681 aaattattta acatatttgc aattaaaatg agaaaaggta aaggttgaat gattgaaaaa
     1741 tttgatgtaa aatagtagct tagtttaata ttatagtttg tagggttaaa aattagaaat
     1801 tgtaagggag ataaattcta tgaaaaaatt agttattatt ttaattagta tcattagtat
     1861 ggttagcttg acagcttgta aaaaaagcaa tgaaagtaaa tataataatt taaacaacaa
     1921 agaatccgga caaacaacca ttgaaatgga cttagataaa aattatgata cttcagaccc
     1981 atttgttaat gcacgtttgt tttgtgtgtc taatgatata gatgttttag acacagagat
     2041 ttcttttaaa atggatggag atagtggtat tgtggaaata aaggacaata aaacatatga
     2101 aactttatgg agtaatacat ggcatggaag cgttgataat gatacattca caatttctct
     2161 ttctaatata caaaaagaga aagagtatgc tatatgcttt actggaatta aaataaatca
     2221 tgcagttgta aaggttactt ttgaaagcaa tttagttaag gagaaagaaa aaccctcaaa
     2281 ataaattcca gattgtctat aacttgatat tcagtacata aaagcagttg atatttatga
     2341 ttgactgctt tttcttatca aaaaggagag tttgtgcatt tttacttgaa atagtttatg
     2401 cacatcaaaa gttggtgagc atgatattgg aaatggtaag catgaaatct tgataagaca
     2461 aggaaataaa tttaagtttt caattaagta tatttccata atttagttaa caataagcta
     2521 attattattt atattttgat atataaataa taattgtagc aaatttcaaa aaatcatata
     2581 ttttttgaac taaataaaaa tttattttta ttattttaaa ttagaggaga ttcttgaaga
     2641 tatattattt ttaaaaataa gtatagttta aaaattcaaa aaaaagatgg caaaatatgt
     2701 cccaagggac attgagtaaa ataaatgatt tcagcttatt tacactaaaa agtacatact
     2761 aaatgagggg taaaataaag aaaaatgata tactaattgt cttttgataa taaaaaaaca
     2821 tggaatttga ttatttaatc aagaaaaagt attgaacaaa tgatttattt agtgtacaat
     2881 aatcatgtaa aaacatagta atggagggag acatttcata atgaaaatta aggtaggaat
     2941 gaacggattt ggaagaatag gaagagctgt attaagaata gctcaagaag aattaggaga
     3001 taatatagaa attgtagcca taaatgcaag agcaacaaca gaatctttgg cacatttatt
     3061 tacatatgat tcatgctatg gaacttttag aggtgaagta gaggcaaagg atgaagacac
     3121 tctagtagta aactctaaag agataaaaat attaagatat aatgacccag aagaattacc
     3181 atggaaagaa ctgggggttg atatagtaat agaatcaaca ggattattta cacaaagaga
     3241 aaaggcagaa aagcatatta aagcaggagc aaaaaaagta attataacag ctccaggaaa
     3301 aaatgaagat ataactatag ttatcggagt taatgagaaa gaatatgata atgaaaagca
     3361 caatataatt tcaaatgcat cttgtactac aaattgtcta gctccttttg ctaaagtatt
     3421 ggacgaaaaa tttggtatag taaaagggtt aatgactaca gtacattcat atactaacga
     3481 tcaaagaata ttagataaaa gccataaaga tttgagaaga gcaagagcag cggctgaatc
     3541 tataatacct accactacag gagcagcaaa agctgtgtca agagtactac cacaattaga
     3601 aggaaaatta aatggttttt cacttagagt accaacacca acagtttcac ttgttgattt
     3661 agtgtgcgaa cttaaagaaa acgttacatc tgagcaagtt aactctgtgt taaaagatgc
     3721 tgctgaagga gaattaaaag gtgttttagg atattgtgac aagccacttg tttctataga
     3781 ttataaagga gattcaagat catctattat agacgctcta tccacaatgg ttatagaaga
     3841 caatatggtt aaggtagttt cttggtatga taatgaatgg ggatattctt caagaactgt
     3901 tgacttagta aaatatgtag ctgaaaaatt aaaataatat atatttctta aagcaaattt
     3961 taaaaaaatt ttttaaaaaa attatataaa actaaaaaaa aagattatga aaaatattga
     4021 aggaaaaatt ttttcataat cttttttctt tcatgcaaaa agatacaagt tacaacttat
     4081 atttgcatat taggtcgtta gagaagtata tatatattta gtaaggaatc atacttttta
     4141 taaaatgaaa gataagatgt cgaaaacttg cataaatctg aaaaattttt attattaaaa
     4201 tactgatttc cattttaaaa atgataaaaa aatgacaaat aaagttgcaa atagtaatac
     4261 ttataagtat aattaaaaaa gagaaaaggt tttgttaaac tttataacaa aaaaagaagg
     4321 gatgattcaa aatggagaag ttaacagaca ggagacaggt taaggcagta agcatggaaa
     4381 ccttcatttt cctaatatta ctagtagttg gttttgggta tgttggtagt attatgggag
     4441 caggaatgat gttcaaagta ataatgagta cagcacatgc tttactattg gagacagttt
     4501 tcttaattat ggctatggca gttcttgcag gcgcattaag cgcactactt tcagagtttg
     4561 gagtaatagc gttaattaat aaaattttcg ctgtatttat gaagccttta tatggactac
     4621 ctggtgctag tatagcagga gctataacaa cttatttatc agataatcca gctattatac
     4681 cttttgctaa agataaaaca ttcacacagt attttaaaca ataccaagtt ccagcattat
     4741 gtaacttagg aacagccttt ggtatgggac ttatcttaac aacatttatg atttctcaag
     4801 gtacagaata tgtacttcca gcattaattg gtaatttagg tgcaattata ggtagtgtca
     4861 taagtgttag aataatgttg acatttacta agaagtttta taaatacagt ccggaagaag
     4921 ataaagcaac aggaacatta gagaaaaagg atgaatttag agaaatcaga gaaggaaatg
     4981 tatttcaaag agctttagat gcaattcttg aaggtggtaa aatgggggta gatatgggaa
     5041 tggctataat tcctggagtc ctagtagtat gtacattggt gatgttatta acttttggac
     5101 catctacaga ccctgttaca ggtcaagaag tttatacagg agctgcatat gaaggaataa
     5161 aattacttcc agttattgga gataaacttg gatttatatt agaaccatta tttggattta
     5221 catcaccaga ggcaatagca ttccctataa cttcattggg agctgttggc gcagcaatgt
     5281 ctctagttcc agagtttata aagtcaggag ctataactcc taatgatata gcagtattta
     5341 cagctatggg tatgtgttgg agtggatatt taagtacaca tattggtatg atggatgcat
     5401 taaatgctag acagttggca ggtaaagcta ttctttctca tacaataggt ggtttatgtg
     5461 caggagcagc tgctcacttt atatttacac tcgtaggata aatgtaatca gctaagataa
     5521 aaaataatat acaaaaaatg gttgttgata tgtaataaga atttacatat caacaaccat
     5581 ttttttctga ctaaagataa tttataatac ataaacatta agtggatatt agagttaagt
     5641 tatatttatg taaaaagtaa caaaaatctg tagaaattta tgacaaaatt tagtacacta
     5701 actatatgtt cttatttaaa atttaaggtt agaattagga attacctagt agagtaagct
     5761 ttgattaata aaagaatcat aaaataaaaa tattagtcat aaagattata aataacttac
     5821 ttaaaataaa gccatagaac ttacaaaaat taaaaaagca tataaatatg gaggggtaca
     5881 atggatgaat tatttcatat aggaattgat gtaggttcta caacggtgaa ggttgtggta
     5941 cttaataata gtaataatat agttcataaa gaatatagaa gacattattc tgatgtaaaa
     6001 aaatcagtta aagaagtact aaatggtata tatgaaaaat tgggagatat aaatactacc
     6061 attataataa ctggttcagg tggaattgga atatcaaaaa aattaggtgt aaaatttgtt
     6121 caggaagtta tatctagtac aaaatcaata gagtattttc atcctgagac tgatgttgtc
     6181 atagaacttg ggggtgaaga tgcaaagata acatatctaa gtggaggaat agaccaaaga
     6241 atgaatggaa tatgtgcagg tggcactgga gcattcatag accagatggc atcactctta
     6301 aagacagatg ccagtggatt aaatgaactt gctaaagggt ataatgttat atatcccata
     6361 gcttcaagat gtggtgtttt tgctaaaaca gatattcaac ctcttataaa tgatggagcc
     6421 aatcagactg atatagcaat gagtattttc aatgcagttg tcgtacaaac tgtgagtgtc
     6481 ctttcttgtg gaagaaaaat agaaggaaat gttgcgtttt tgggtggtcc attgtacttt
     6541 ttatctgaac ttagagaagc atttaaaaga gtattagatt taaaagatga aaacataatc
     6601 ttcccagaaa atgcacaact ttatattgct attggagcag gattattatc agtagatgaa
     6661 gataatatac aactaaaatc tctaatagaa aaattggata gtataaagaa tattgaagat
     6721 ggagaagtaa atttattaga acctttattt aaagataaaa atgagtatga agaattttca
     6781 agaagacatg aaaaagaaaa aataaattat gtggacataa attcaataaa aagcaattgt
     6841 tatttaggaa ttgatgcagg ctcaactaca actaaagcag cacttattga tgaggatgga
     6901 agacttgtat attcttatta taatagcaat gaaggaaatc cattaaaaac aaccattaaa
     6961 gttataaatg aagtatatga tatattacca aaaaatatta aaatattgag ttcaactgta
     7021 actggatatg gagaaggtct tattaaaaaa gctcttaaaa tcgataatgg agagatagag
     7081 actatagcac attacaaagc tgctaaattt ttcaacaaag atgtagattt tatacttgat
     7141 attggtggtc aagatatgaa gtgcctaaaa ataaaagatg gagtaattga taatataata
     7201 ttaaatgagg cttgttcatc aggttgtggc tcatttttag agacatttgc aagttcttta
     7261 tctatgacaa tagaagaatt tgcgcatgaa ggtatttatt ctcaaaatcc tgtagattta
     7321 ggttcaagat gtactgtatt tatgaattct agagtaaaac aagctcaaaa agaaggtgca
     7381 agtgttggag atatatcagc agggctatct tattcagtaa taaaaaatgc tttatttaaa
     7441 gtaataaaga ttagagattt aaatgagatt ggtaataata ttgttgtaca aggtggaacc
     7501 ttttataatg atttggtgct tagaagcttt gaaaaactaa ttggaaaaaa tgtaattaga
     7561 cctaatattt caggaattat gggagctttt ggttcagcac ttatagctaa agaaaaatat
     7621 gaaagtggat acaaaacatc cttgttatct aaggaagagt tgaataatat caagctagaa
     7681 gcaagtgtaa ctagatgtaa aggttgttca aatcattgtc ttcttacaat aaataaattt
     7741 tctgataatg aaatttttat ttcaggtaat agatgtgaga agggtgaagc tatttatggt
     7801 gataaaaaaa taggattaga aaagaaaaaa ccaataaatt tatttaagta caaatacaat
     7861 agaattttta gatacaaacc attggaaaaa gaagaagcaa aaaatgggga aatagggata
     7921 ccaagagtat taaatatgta tgaagattat ccattttggt ttactttttt caatgctatg
     7981 ggctttagag ttgtactttc agataggtca tcaaaacagt tatatgaaac tggtataact
     8041 agtattgcat ctgaaacagt ttgttatcca ggaaaattag ttcatggaca tatagaaaat
     8101 ttaattgcaa aaggtataaa aaatatattt tatccaagtg taacaaatga aaataaagag
     8161 gattcaaatg cagataatta ttataattgt cctgttgtaa tatcatattc tgaagtaata
     8221 aaaaacaatg tagagaatat aagaaataag aacataaatt atataaatcc atttataagt
     8281 ctaaatgata aggaaaaatt gaagaaaaga ctctatgatg aattatcaag acatttttct
     8341 gatataaaaa taactaaaga agaagttaat catgcagttg ataaagctac tgatgaacag
     8401 aatttattta aaatggagat acaagcagca ggtgaaagag cacttaaaga aataaaagaa
     8461 agaaatatga aggggattgt gttatgtgga agaccatatc atatagaccc agaaataaat
     8521 catggaatgc cagagcttat aaattcatta gatatggcag tgcttactga agactctata
     8581 tgtcatttag ccaatgtaca aagaccactt agagttgtag accaatgggt atatcattca
     8641 agattgtata aagcagctag ttttgtaaga gataaaaact atttggaact tgttcaactt
     8701 aattcatttg gctgtggatt agatgcagta actacagacc aggttcaaga aatacttaat
     8761 gaaaaatcga agatatatac tattataaag attgacgaag gcaacaattt aggagcagct
     8821 aagataagga tgaggtcctt aaaagcagct atgtttgaga gagaaagcaa aaatatagat
     8881 gtaaaaaata taaaggtaaa caggatacag tatgctaaaa ataatcagat aacgaacaaa
     8941 catactatat tagcaccaca aatgtctcca atacatttcc aattccttga aaaagctgtt
     9001 aacttaagtg gttataatat agaaattcta aaagatactg atagtagtgt aattgaagaa
     9061 gggttaagat atgtaaataa tgatgcatgt tatccagcta taatagttgt aggtcagcta
     9121 ataacagcat taaaatctgg caaatatgat ttaaataaca cttctgttac tataactcag
     9181 actggtggag gttgtagagc tacaaattat attggattct taagaaaggc tatatacgat
     9241 gctggattta aagatgttcc tgtcattgca cttagtgtaa atggaataga agatagtggt
     9301 ataatggata atatatcact aaaattaatc aatagactct ttatgtctgt tgtttatggt
     9361 gatttgctga tgaaagtact atatagagtt agaccatatg aaaaagttac tggaagtgca
     9421 aatgctctat atgaaaaatg ggttgatata tgcaaatctt ctcttgttaa agcaaaaatt
     9481 tctgtattta ctagaaatat aaaagatata gtaaaagaat ttgataattt agagatacta
     9541 gatatcaaaa aaccaaaagt aggtttggtt ggagaaatat tggtgaaatt ccatccaatt
     9601 gcaaataata atttagtaga tatattagag cgagaaggtg ctgaagcagt cgtgccagac
     9661 cttacaaatt tcttcttaag ttgtgccttt aatactatat acaaacacac tcatttagaa
     9721 ggaagtagaa agagtagaat gataggagag gcatttatat acataactgg aatatatcaa
     9781 agagtatata aaaaagcact tgataagagt gagagatttt atgctccagc caatataaaa
     9841 aatgttgcta aaagtacaga accagtagtg tcattaggta atcaaactgg agaaggttgg
     9901 cttttaacag gtgaaatggt tgaattatta aatgaaggtg tagaaaacat tatttgtatg
     9961 caaccttttg gatgtttacc taatcacata attggtaagg gttctataaa agaattaaag
    10021 aggttgtata aaaatgcaaa tataatacct attgattatg acccttctgc aagtgaggta
    10081 aatcaactta acaggataaa acttatgctt tctaaggctt ttaaaaatat ataagattta
    10141 tattttgata tgttaaaagt taatgaattt aaaaatatac tctatattaa gtatctataa
    10201 aaaagagtta tcctattttt tagggtaact ctttattagt taaaaaatta tatgtatact
    10261 gatattaaag gggggaagta atatgagttt agtatatgat gtttataaat caaaattagg
    10321 aaatttgtac atattaagtg aagatggttt tatagttagt atatacatag gagatgaaaa
    10381 atttaataat ttaaaaaatg aatgtattaa aaaaggaatt gatataaaga gaagtaagga
    10441 agatttaaag gaagcaataa gccagataga tgattacttt aatggaaaaa gaaaagtctt
    10501 taatttaaat attcgtattg aagggactga atttcaaaaa tcagtttata gggaaatgtt
    10561 aaaaatacct tatggagaaa cattgtgtta ttcagatata gcaagaaata taaacaatcc
    10621 aaaatcagta agagcaatag gacaagcaag taaaagtaat aaaattccaa taataatacc
    10681 ttgtcataga gtagttggca aaaaagatat tggtggatat atggggaatc attctgattt
    10741 gaaagagata ctattaaatt tagaaagaca gagttaactt agaaagaaat gtttttattg
    10801 ttaatatttg atataataat agtaaaaaga agtatttttt acaaaaacaa tgaagaattt
    10861 attttaattt acaaaaatga gggggaattt taatgtgtga taaagttata gcatcaaaat
    10921 atcatgagaa gggatttaat tgtgcagaat cagttataaa agcatataat gaggaattta
    10981 atacagatat accagtttgt ttaggaagtg gactgggttc agggtgtggg gttgctagtt
    11041 tatgtggtgc agtaaatgca tcaaatataa taattggata tgtaaaaggc agaaaccacg
    11101 aagatgaaag tactaaagct aaagtatatg ctaaagattt aactacaaca gtaagaaaag
    11161 agtatggttc agagttatgt atagacctaa aaaaagattt agttgcttgt agagaaataa
    11221 tggatttcgc atatgatagt ctaaaggaaa ctttaaaaaa agaattataa gaaaataagc
    11281 tatcaaatat aaattatttg atagcttatt tttatagccg atactaaata aatcaaatat
    11341 attttagaat tattatttgt aaataaacag caaataattt taggcttttt atttaatata
    11401 gtttttattt atatttattt ttgaatatgt tatactttgt ttaaataaat atttgtaatg
    11461 agggagatga gaagattgaa gaatctcaat ttacttatta ataaattata ttcaaaaaat
    11521 cataatgaag catataaaac ttttttattc ttagaaaatg aaagtttaaa atcaaatatt
    11581 acatattgtt tttttgactc attcctagaa atgattgata acgaaaactc atatattcga
    11641 acaaggggat tgttattaat ctctgcaaat gctcagtggg atattgataa taaaattgaa
    11701 ataaatatag atagtatact aagtcatatc gtagataaaa aaccttctgt atcaagaatg
    11761 tttattaaat ccatacctaa tattacaaag tataaagaaa atcttattaa tcgcataaaa
    11821 atggaattaa gtaatgcaga tataagtatt tataataata atatgaaacc attagtagaa
    11881 aaggatataa acgatacatt atctaatatt agttaaatat taatatagaa attgaatatt
    11941 atctagttac aattatttat aactaagata ataaaacaac aatggtgcta atttatatgt
    12001 ataaattaat tatgaaaaat ttatataagt aaaatatatt aacataaagg taaaattttg
    12061 tatactaaaa gggaatattt acagtttaat ggcagtttta aaataataaa ttaaagctgt
    12121 catttttatt taaaaatttt tagaaaaagt acaatagtgt taatgtgtga attagataag
    12181 gtgtatataa tagtttagat gatatgatat aaaatatgtt gtaaattaaa tgttttcttt
    12241 gacaatatat acacaaggat gataatatct atatgaataa aagatagtgt gtaatttgat
    12301 aatatgtaat tataacatta tgatataatt acaataaagt atgtaataat ctgtagaaat
    12361 ttcaagctag ttatctaagt tttcggataa ctaaatctaa acggaataca taatgtatta
    12421 aataaatgat gatactaaaa tgatactatt tttatagaaa tttattgagg tatataatta
    12481 atgaaaataa tatattaaat tatataaatt aaattatata atatattgag ttttacataa
    12541 aagcaaaggt gggaataaaa atgaaagaaa ttgctgatgc tataacatca gagtatttaa
    12601 gctatggtat caatgaagat attagtatct atgaaggtag attttgcata tatttagata
    12661 aaaaatatag atgtaatggg aaaatttatt ataaaatgac acctccaata tctataagtt
    12721 ttaaagcaga cataggttgt gttgaagaga tagacaatga agatgacaat ttagctttag
    12781 attatgataa tgctattctt gaagttcatg gatataaaat tatttctata acaataaata
    12841 ctttaagtga atttagtgta gaaggttata tcaatgatga ctgtataaaa tctaagaact
    12901 cctatgttga atatgtagat tttaatataa taaacttaga taaaatacct ggaaaactca
    12961 ttaaatacaa tgataaggta tacgcaggta gaattgaatt tgatataaat gattatgttg
    13021 taactataga caagcgatat gattatagaa aagaattaaa atcagaatta aagtctaaat
    13081 ctggagcaat aataactcat ataggcagga ttagaagaaa agatggtaga atttttagaa
    13141 caaataatac aataaatctt ttagatagga tatcaacagc tttgagtttt atgtgtggaa
    13201 gatatgtagg gttttgtttg gccaaagggt atagaagtgg taatgaagtt tatagaatat
    13261 ggaatgaaaa tcaaatatct ccttttagat atgtaccaac atggtcagat acactttcaa
    13321 attatcataa tatggaaaaa tatataagcc ttatgtgtaa aaagctagaa gatttttatt
    13381 atggttctgc tataaagagt gttgttgatt ggtacataga atctcttgga agtgctacca
    13441 tggaaaacaa tataatatct gtacaaattg cacttgaaac tttgtcatat gtaattctag
    13501 tggaacaaaa taagatactt acagatgaag catttgactg taatttggca tctaaaaata
    13561 taagactctt acttgataca tgtaagatac catatggtaa acatgaatta aatatatttg
    13621 ataatataat aaaaaataaa tttgatgatg gagtggattt agttatttat ttaagaaata
    13681 gcatagttca tccaagtaga aagactcata gagctgtgtt agaggttgaa gatatttgga
    13741 atataatttc aataggaacg agatatattg aacttgtttt actctttatt ttaggttata
    13801 gaggagaata ttcaaacaga ttagtagaaa gatgttatgg tgaagtggaa gttgtacctt
    13861 ggaactagat ttttatattt attttaaaat atatattgac atatattgcc ttatgctata
    13921 aaatcaatat cataataata attcagaata acattaaatg ctaagaaaag aaatagtaaa
    13981 agtagttaat cttaaacaga gagtttccga ttggtgagag gagcaataga ttttactttg
    14041 aacacatctt tgagcaggac tctgaaagag tagaaatact ttattaggag atttccggaa
    14101 tccttgcacc cgttatagtg ctagagtata ataattttat tgtacttaaa gaggttagtg
    14161 ccgtgaggca ttaatgaaca gaggtggaac cacgagagtt aactcccgtc ctctagcaga
    14221 agctagaggc gggagttttt taatataatt ttttaagcgc gcagagaatt atattgcaat
    14281 agatacactt tttaaaaaat aatcaaaata ttttaaaaat taaaagacga gggagaatat
    14341 tatgaaaaat atattaaaaa aagtaggaat atttacaatt atgttaggtt tattaggtgg
    14401 agttgtaggt tgttcaaaac cagataatga aaaagataag gatgcttcaa aggaatctaa
    14461 aaaagaagta gttgtagggt ttgataatac gtttgtacca atgggatttt tagatgaaaa
    14521 gggagataca gtaggctttg acgtagactt agctaaagaa acatttaaaa gacttggaat
    14581 ggaagttaag tttcagccta tagattggtc aatgaaggaa actgaattaa atgattcaaa
    14641 aactgtagat gtattatgga atggatattc tataacagac gaaagaaaga aaatagtatc
    14701 atatacagaa ccatatttac aaaataaaca gataatagtt actctaagtg actcaaaaat
    14761 aaattcaaaa gctgatttaa aagataaaga agttggaaca caacaaggtt caacagcact
    14821 tgatgcagtg gaaaaggata aagattttat gaatagctta aaaggtggag caccagttct
    14881 ttatgatact tatgataaag cacttagaga tttagagata ggtagaacta gtgcagttgt
    14941 tggtgatgaa gttttaatta gatactatat gggacaaaag ggtgaagaca aatacaaggt
    15001 attaaaagac gattttggat tagaagatta tgttgtagca acttctaaag aaaatccaga
    15061 actttgtgag aaaataaatg aaacattaaa agaaatgaaa aaagatggaa cttttgacaa
    15121 gatttatgat aagtggttta aatagaagat aagttagctg ttaagaaggg ggcactaaag
    15181 gcatgttaca aggtttagag atagttatag caatgttttg tataacattg atagtatcaa
    15241 ttccattggg gattggagtt gcatttttaa gattatcaaa gaataaatta gtaagtggta
    15301 ttacacaatg ttatatattg ataatgagag gtacaccttt acttttgcaa atgatagtca
    15361 tattttacgg attacctctt ttaggaattg tatttgacag atttacagct ggagtagtag
    15421 ctttcttctt aaattatgca gcatattttg cagaaatatt tagaggtgga atacagtcaa
    15481 tcgatagagg acaatatgaa gcttcaaaag tactaggatt tgataagttt actatgtata
    15541 agagagtaat ctttccacaa gtttttaaaa gaatactagc acctatttca aatgaagtaa
    15601 tcacattagt aaaagataca tctttagtat atatattagg attaaatgat attttaagaa
    15661 tatctcaaat agcaatgaac agggaagcaa gtctgttacc attatttgag gcaggagcga
    15721 tatatcttat atttgtagct atacttacta agggatttga attacttgaa aaaaaatatt
    15781 cttattatag ataaagttac aatattatag gaggaggttt tttatatgtt gaaaatcaaa
    15841 aacttaaata aatcatttaa aaaaaataga gtacttaaag atatttcttt tgagttagaa
    15901 gaaggtcaga ttggagtttt acttggtaag tctggtgcag gaaagaccac aatattaagg
    15961 tgtataaatg gtcttgaaga atttgatagt ggagagatta taatagataa tgaggtaata
    16021 aaaaataaga gagatatggc aaaaatacga ggaaaaatag gtatggtttt tcaaaatttc
    16081 aacttatttc ctcatatgac agtccttgaa aatataattg aatccccagt taatgttttt
    16141 aaagttccta gaaaagaggc tgaagagagg gctagagaac ttttaagatt agttgattta
    16201 gaagataaat taaattctta tccatttgaa ttgtcaggag gacagcaaca gagagttgct
    16261 atagctaggt catgtgcatt gatgccaaaa gtcctttgtt ttgatgaacc tacttctgca
    16321 cttgatattg atactattca aagagtagtc aatataatga acagacttaa agacaaaggt
    16381 atgacaatat taataattac acatgatgtt gtcttctcaa ataatgttgc agataaaatt
    16441 ataagtataa aagatggtat agtagaaaat gttcaaataa aagaaaaaat tgtttagagt
    16501 tttataaata taaactaggg tagaatttta taatataaat aaagggcaag taaaatcaaa
    16561 tatactatgc ccttttgtta tctcaaaatt taatcttata ttttatgttt aagttacatt
    16621 ataatttata ataaaaataa aaggactatt taaatatata atgtgaataa atgtttaata
    16681 atttgaaata tgataatttt ttatgttgaa agcttataat gattatgata taaattggtt
    16741 atagtataca atttatgggt ataacaataa aaaattagaa aggaattttt ataaaatgat
    16801 taaattatat ggatatacaa aatgctctac tgttaaaaaa gctaaaaatt ggcttaagga
    16861 aaataattta gaatttgaag atatagatat ggttcaaaac cctcctagta aagaggagtt
    16921 aaaatcaatt tataagacta gtggatatga tataaagaaa ttttttaata caagtggtat
    16981 gaaatataga gaattgggtc ttaaagatat tgtaaaaact gaatctgatg ataaactttt
    17041 agaaatattg gtaagtgatg gtatgcttat taaaagacca ttacttttgg atggtaaaaa
    17101 tgtattattg ggctttaaag aagatgtatg gaaaagtact ttgctaaaag aagattagga
    17161 agagataggt gtgttgatta aaattattaa ttaatacacc tataaattta tgtattaaat
    17221 ctaattttta taaatattaa ttagcaaatt caaatcaaaa aaattcatat caacaaacat
    17281 attacttctt attacaaatt atatcatatg ttttatatta aaatattata atattacaac
    17341 gaattgttac aaaattactt attattaacc atgaacattt gttttgtgct atcatattta
    17401 tataagggaa ttgtcataaa aaatatcttg ttcatacagt tttatataga aaaaagaaat
    17461 gaatcttttc tttatataag tatattttgt aaattgcctc tatatttata gtttaaataa
    17521 tagtggtatt aaaaatctga caacaaaaat aaaactttca aaaaattaaa tctaaaaaga
    17581 ataggagata aatatgagta ttgaagattt atatgatttt gaatgtgttc ctttgaacaa
    17641 tgagattgat attgatgttt tatttgaaaa gatgatagaa gatggaaaag aaaaagaata
    17701 tacaccaatt atagtcattg atgaaaaagt agggctatta agaaaaaata tagatatgat
    17761 tactaaagag tatggttctc ttgaaaacta tagagagtat tgtttaacaa aatataatga
    17821 aattgatgta aatcaatttt ttgattttag gaagagtgag atttcagaat tattaaagga
    17881 gctaattgat ttagaagatg atttttatga ttataaacat tttagaccaa ttatgaatat
    17941 agatatattt catgaatata acaaagttta catagctaaa attccaacaa ttaaaccata
    18001 tgaagtattt gcatacatac ctattggcgg atttaatgat tgtcctagag atgaagaaca
    18061 tatagctatt gcaaaatatt ggtatgaaaa gcatggaatc tttccaatcg caattggatg
    18121 tgatacagtt caatattctg taaaaaattt aactaaagat ggtaaaaaat ttgatgaatt
    18181 atgtattgaa ttagtatttt attgtgagga tattattata caagggtatg aaaccttaaa
    18241 ggctcttaag gatgtattaa aacgctctac aatagtgctt ttttggtggg attgatattc
    18301 catcatttag atagtattaa attgttagtc accaagaatc cacttgcttt agttatgggg
    18361 agtgtgtcaa actaggtttt tatacacagt gtagcatagt aatatgttta aattacaaag
    18421 gttaaaaaaa tactttaata tttttaatat tataattaat agatttaaag gtaattataa
    18481 tttataaaat aaatacttta tatgttataa tcattaagaa tgtaaaaaaa taatatatag
    18541 ttttatagtt catatttttc cagatatgga ggtaaatttt gtgaaggaaa aagaaaaatt
    18601 agataaatta aaaaaaatgt tacttgaatt aggcagtgtt gtagttgctt attctggtgg
    18661 agtagatagt aattttttgc ttaaggtcgc aaaagataca ttaggtgaaa atgttatagc
    18721 tgtgactatt catgcaatga tgcattcaag tagggaaatt gaagaggcta aacaatatac
    18781 tcaaaatttt ggtgttaaac atatcatatt aaatatagaa aactttgatt taaaagaatt
    18841 taaagaaaat ggtgttgata gatgttatca ttgtaaaaaa tatatattct ctaaaataaa
    18901 agaggtagca aaagaacata atataaagta catagtagat ggaacaaata tagatgattt
    18961 aggagactat agacctgggc ttaaggcatt gagtgaatta ggagtaatta gtccattaaa
    19021 agatagtagt ttaaaaaaag aagaaattag gtcgctttca aaaacattag gattaaatac
    19081 ttttaataaa ccatcatttg catgtcttgc gagtaggata ccttatggag ttgaaataac
    19141 agatgaaaat ttaagaatag tagaaaagag tgaagaatat ctatccaatt taggtttttc
    19201 tcaatttaga gtgagaatgc atggagatat agctagaata gaagttggac aggaagaact
    19261 aggtaaattt tttgaaaata acaattttaa taaagttgat actaaattaa aaatatttgg
    19321 ctttaaatat gttacactag atatgtcagg atataaaatg ggaagtatga atttaaatgt
    19381 gtagattatt ttaaaaataa ataagtttta tagttaatat aaggaaacag gaggttttat
    19441 gaaaaattat acgttaatat cgccatgttt ttttggaatg gaaaaaatgc tggctagaga
    19501 gattactaat ttaggatatg aaataataaa aacagaagat ggaagaataa catataaaac
    19561 tgatgagttt ggaatagcaa agtcaaacat gtggttgaga tgtgctgaaa gagtacatct
    19621 taaaattgct gaatttgagg caaaaagctt tgatgaatta tttgaaaata caaaaagaat
    19681 aaactggtct agatatatac cttatggagc tcaatttcct atatcaaaag cttcctctat
    19741 aaaatcaaaa ttatacagta caccagatgt acaagccata gtaaaaaagg ctatagtaga
    19801 aagcttaaag aaaagttatt tggaggatgg tttgcttaaa gaagataagg agaaataccc
    19861 tatttttgta tttatacaca aagataaagt aaccatttct atagatacaa caggagatgc
    19921 tttgcataag agaggatata gagaaaaggc aaataaagct ccaataagag agactttagc
    19981 tgctgggctt atttatttaa ctccctggaa agcaggtaga gttttagtag accctatgtg
    20041 tggttctggt actatattga ttgaagctgc tatgattggt ataaatatgg cacctggctt
    20101 aaatagagag tttatatcag aaaagtggag aactcttgat aagaaaatat ggtgggatgt
    20161 aagaaaagat gcttttaata agatagataa tgaatctaaa tttaagattt atggatatga
    20221 tatagatgaa gaatctatag atatagctag agaaaatgct gaaatagcag gtgtagatga
    20281 atatatagag tttaatgtag gagatgcaac tcaatttaaa agtgaagatg agtttggatt
    20341 tataatcact aatcctcctt atggagaaag attagaagat aaagacagtg ttaaacagtt
    20401 gtataaggag cttggttatg catttagaaa attaaaaaat tggtcgtatt atttgataac
    20461 ttcttatgaa gactttgaat atgagtttgg gcaaaaagca gataaaaaaa gaaaattgta
    20521 taatggtatg ttaaaaacta actttttcca atatccgggt cctaagcctc ctagaaataa
    20581 taaataagtt ttacatgatt tatttgtaaa atataaaatt ttattaaaat aagtaaaaca
    20641 ttatgatgcc ttgaaacgtc taattattgt gaggagattt ttgtgaacaa atttaaagat
    20701 ttataggatt aggaggagtt aaatgaaagt gttaaagctt attactgtag tagccctgat
    20761 gatgttattt gttactggat gtaatataaa aactgaatct ccagaacaat tagcgaagat
    20821 acctgactat gatgatacaa aaaaagtatt gtatgatggt attgaccagt tactaaaacc
    20881 agattcatct atgatattgc cttctaatac aaaagaagta ggaaaaataa ataaggtaga
    20941 tttaaacagc gatggaattg atgaattagt agtatttgaa caaaaagaag atttaagtaa
    21001 taatgtgagt caggtagggt ttgtaacctt gagttacaat ggagaaaaat acgtacttgg
    21061 agaccatttt ttagaaaatg gcgaatcaat agaatatgct aatttttatg atttggactc
    21121 agatggatat aaggaagtta tcttattggt taaatccaaa gacaaaacga atatgcatat
    21181 atataaagta gtagataatg aaataacaaa aatatatgac ttggatgcat catggcttca
    21241 aaataaagaa gattttaatg atatgaaagt aaaaattgga tatatagatg gagatgacaa
    21301 gttagacata ttgatgcttc atttgaataa taagactaat gaaatgtttg caagtgttgc
    21361 aaattttgat gggaaaatga aaatcaaaga ttctgttaag tttgaaaatg taaaaaactt
    21421 aagtgaatta tatataacat taggtaatgt tgcttcatct gttggaaatt cttctgcagc
    21481 tataaaaggt attgtacttg atattcctat attgaaagat aataactata ttacgcagat
    21541 actttatatg aaagatggga aaattaacaa agcttttagt gattatgata aaactattac
    21601 taaatcttat tatatacctg tagatgatat tgacaaagat aagattatag aaatacctat
    21661 agttgcaggc agtacaggta ataataaaaa tacttatagt tctaaatcat ctgcaactat
    21721 aagttggtat agatggaatg gaaaagaagg tgctgactca agtttaatat ttacaagtca
    21781 gatatattat aattataaat ataattttaa attatttatt ccaaataatt tatttgataa
    21841 aatacttgtt gaacaggaat ttgttggaga aaaagcagta tttaaatttt actattttga
    21901 ctattcagac cgtaagaatt tatttaatat agtagtagag agtaaaaata aacttgaaga
    21961 tagaaaaaat acaggtactc aaaattctat tgtacttcaa gagagcgatg aatatacttt
    22021 cttactagtt gtaaacaatg caaatgaaat ggataagcta gatatgacta tagacgcatt
    22081 aaaagaatat ttctcattaa tatatggtta atattatact caattggagg ttttatttta
    22141 tgaaggaaaa gatacttata ctagaagatg aaattggtat tagaagtttt gttagtataa
    22201 acttaaaaag ggaaggctat gaaatagttg aggcaggtac tggaagagaa gctatagaaa
    22261 aaatgacaac agaaaaggat attacaatag ctcttttaga tgtaatgctt ccagatataa
    22321 gtggtataga agtatgtaaa tttataaggg agaattttga ccaagtaggt ataataatgc
    22381 ttactgctaa agctcaagaa gatgataaaa tagaaggatt tatctcagga gcagatgatt
    22441 acatcataaa accatttagt ataaaagagc ttttagtcag agtttctgct cttcttagaa
    22501 gagtagcaaa ggatgattca agtgttaagt cgagtgagat agtttctcca ccatttatac
    22561 ttgatataga caaaagaaaa ttatttaaaa atggaaagga aattgagctt acaccaactg
    22621 aattttcaat agtgaaatat ctaatatcaa atgctaagca gtcgttaagt agagaccaga
    22681 tattagacga agtatgggga actaactatt tatatgattt taaaatagta gatgtaaata
    22741 taagaaggat aagaaataaa atagaagatg acccatcaaa accaaaatat atacaaacta
    22801 tttggggtta tggatactgt tttagaaagg aagaataata gtgttacatt ttgaaggtct
    22861 gagaaaaaaa gtaataaaaa actattttat aataattatt ataatggtta ctctgtttga
    22921 aggattgttc atgttttaca tacaaaacta ctattatgat tctgtcaaac agctacttga
    22981 atctgaaata aaatatgctg atgaatataa tgctattaca atggaaacta caagttttga
    23041 gaaaaaagta aaaaatatat ttgataaaca acccttaact aaaaattcag aatttggaat
    23101 ttcaataata gataaagata aaaatattat attagaccaa tatggtttta aaagtaaaga
    23161 aaaagcaaac tatgaagatg ttaacaatgc attaaaagat ataaaaacta aaaatttaac
    23221 accttatact tatagaatac cagatacagg ggagcatgtt atgagtatct ccttaccact
    23281 taaggtaaat aatataatag aaggtgttgt tagatataca gtatcattag atgctattga
    23341 taatgcaata ttaaagcaag ctacatggct tatattagca ggaatattta tacttattat
    23401 agctatacta ataagtctta aatttgctga gactcttata aaaccattac gagagctaaa
    23461 gaaatttgca aatgaattgg ctgtaggaaa ttataatata aaattagaaa agatgaagat
    23521 tgtagatgat gaaattggtg atttagcaca gacatttgaa cacatggcac atgagattga
    23581 caaaagtgaa aaattaaaag aggaatttat atcatctgta tctcatgaac taaggactcc
    23641 tcttacatct ataaaggggt ggagtgaaac cttaggttat gaaagtataa caagagaaga
    23701 actagactta ggtttaggca ttatacaaga tgaaacagaa agacttataa aactagttga
    23761 agaattatta gacttttcaa ggctttcttc agacaggata aaacttcatg ttgatatagt
    23821 tgatgttgaa ggtttaattg taggtgttgt aaatcaactt aaagttaaag cagctgaaaa
    23881 agatatatca cttttatttg aatttgaaaa tgaatttata gagaacattc aaggagataa
    23941 aaatagatta agacaggttc tcataaattt aatacaaaat tcatttaaat ttacgagtca
    24001 aggtggttac ataaaagttg tagcttctca agatgaagag ataacaacca tatcagtaga
    24061 ggataatggt tcaggtatag aaaagcaaaa tttaaataaa gtgttagata aatttttcca
    24121 agaagattat aataaggctg gtagtggatt aggactagca attagtaatg aaattgtaaa
    24181 acttcatggt ggaagaatga aaatagaaag tgaaaagaat gttggaacaa aaataacttt
    24241 taatataaaa aataaatttg ctaaacaagc ataaattctt agaaagagga ttaagatgag
    24301 aaacataaaa atgatagtag catacgatgg ttcaagatat aaaggatatc aaaaattagg
    24361 tgacaataat atgactattc aagaaaaact tgaaaatgtt ttaagtaaaa tgactaatga
    24421 aacagtggag ataataggtt ctggaagaac tgatatggga gctcatgcaa gaggacaagt
    24481 ggtaaatttt agaactaatt gtatggattc tttggataaa attcaaaaat atttatatga
    24541 atatttacca gaagatatag ttgtaaaaac tgttgaagaa gttgatgaaa gatttcattc
    24601 aagatacaat gtaaaatcaa aaacttatat gtataaaatt gacaataata agtatcatag
    24661 tccttttata agaaaatatg ctactcatgt aagtaaaaaa ttagatttag atagaatgag
    24721 aaaagcaagt gagtatttag taggagaaca tgattttacc agttttgctt cttctaaatc
    24781 taagaaaaaa tcaaatgtaa gagaaattta ttctataaat ataaaagaag atgataatgt
    24841 tatagaaata tatgtagaag gaaatggatt tttgtataac atggtaagga taatagtagg
    24901 tgctttaata gatgttggtc taaaaagaag agctccacaa gatattaagt atatgcttga
    24961 atcaaaagat agatgtcaat catcagatac tgcaccagct aaaggactat gtctttggaa
    25021 agtaacatat taatcaatta tataaaactc tctttaaaat aaaaataaaa taaattatat
    25081 agttgacata aatggaaaaa taaactatta tatattttat aagagagata taaaacttta
    25141 tatttaaatc ctgtgagaaa gagagtaact tctatgtgtt ttatagagag ctgaggatgg
    25201 tggaagcttg gcaaataagt attagtgaaa agaactttgg aggatactaa ttgaatttag
    25261 tatgttagta ggtaatctcg ccttaagaga aagagtggat aagtttatct tatcaattag
    25321 agtggtaacg cggatatatt tcgtctcttg gtttttccaa gaggcgtttt ttaatatatt
    25381 taattattag tgtttatctg gtatgttgaa catttactaa ttgattagct aagtttatca
    25441 ataagagtgg taccgcggat atttcgcctc ttagtatttt aaaatactaa ggggtttttt
    25501 tagtattaaa atgattttat gtgagtctaa attctcagag tcattcaata ttaagaattt
    25561 ctataaaata aaaattataa tttaagattg ggaggaatta aaaatgaagg aaaaagtagt
    25621 attagcatat tcaggaggac ttgacacatc aatcataata ccttggttaa aggaaaatta
    25681 tgaagatata gatgttatag ctgtttgtgg aaatgtaggt caggaagata aaatggaaga
    25741 tgtatatgaa aaagctttac aaagtggagc atcaaaggca tatgtggatg atataagtga
    25801 agaatttgta actgaaacta tatttaaagc cgtaaaagca gaggctaaat atgaaggaaa
    25861 atacttatta ggaacttctt tagcaagacc tataatagct aaaaaattag ttgaagttgc
    25921 tcataaagaa ggtgcaaaat atatatgcca tggatgtaca ggaaaaggta atgaccaagt
    25981 tagatttgaa gctacaattg cagctcttga cccgactata aaagttattg caccttggag
    26041 aatttgggat ataaaatcaa gagaagatgc tatagactat gctgaaaaac ataatataaa
    26101 ggtaacagca actaaagcta aaatatattc agtagatgct aacctttggc atgtttcaac
    26161 agaaggtgga gatatagagc acctagaaaa tgaacataaa aaagatgttt ataaacaatg
    26221 tgtagaccca gaagatgcat gtgatgtagc tgaatatgta gaagtttact ttgaaaaagg
    26281 tgtacctaaa aaggtaaatg gtgaagaatt atctccagtt gcactgattc ataagttaaa
    26341 tgagttgggt tgtaaacatg gaattggtgt tatagatata gttgagaata gacttgttgg
    26401 tatgaaatca agaggtatat atgagactcc aggaggaaca atcctttatg aagcacataa
    26461 tattttagaa agtgctactt tagacaaaga tacattacat ttcaaacaaa tggtatctta
    26521 taaatacgga gaacttattt acaatggact atggtattgt aaattaagag aatctataga
    26581 tgcatttatg gaacaaactc aagataatgt tacaggaaca gtaaaagtta aactttacaa
    26641 aggaaatata aaacctgctg gaatatttac tgaaaatgct ctttatgatg aaggaatatc
    26701 ttcttttgga aatagtgaac tttatgacca caaagatgca gaaggattta ttaatttatt
    26761 cactttacca ttaaaaatca gagctatgaa agctggaaaa taataaaata aattatttaa
    26821 gagtgtataa aaactatttt taggttttta tatgctcttt ttttatttga atttattaac
    26881 ttatacagta aatagtataa aaaaatatat tatagttcca aatggcttaa taatgtgaaa
    26941 atataagacc taaaatataa attttataaa tacaatagtt attgactctc tcattgtaag
    27001 agggtttata ctgaatctaa tgaaaattta tagtgaggag atagattata tgagaaaaat
    27061 aattgaaatt aaacatcatt cacatgatta tgagtgtatg tggaatggta tagaagattt
    27121 atatataaat aaaaccggtg aatgccttcc aaacgatttt ttctttttac tgtcaggttt
    27181 tggttcattt tgttatatga aaacaaataa agctgatttg aaaagaatgg tagctttggg
    27241 agatggaagg acaaaacaga tgtataaatt tttagcacca attgttggat ttgaatacaa
    27301 acatcatgag tttaaaaagt atgagcaagc attaaagaaa gcaaaatctg aaattgatga
    27361 tggatatcca gttattttag gagctttaga tatgtattat ctaccatatt ataagaagct
    27421 atatcataaa gaacatattc cttttcatta tatattaatg gtaggatatg atgatgaagg
    27481 aatatatctg tatgattgtg gtagaacaga attattacat ctttcttatg ataaattacg
    27541 tgaaagcatg aattgcaatt cccctggatt aagcaaagaa aatactattt gcacaataag
    27601 aatgaatact tcaaagaata aatataacat tgctagagaa gctattgcta taaagcgtga
    27661 tatgttttta aatccaccta aaggattttt gggatataaa ggttttgaaa agtttattaa
    27721 agagttgcca cagtggaaca ctgaattgga taaagatgat tatgataaga ttttgaccaa
    27781 tatggttatg ttttttggaa cagtaccaac aattccaaat gcaatcaaag gaattaaaga
    27841 accagatact gttcaattta aaggtggatt tgataaaatg agtagaatgc tcaacagtat
    27901 tggggaggaa tacaaaaacg actcttttat acaagtagct gatatttttg ataaaactgc
    27961 tattataatt gagaaaatat ccaatattat aatagattac ttaactcaaa catgtgatga
    28021 tacaggacaa cttccgttat tgttctctga ggtcttagag catatgaaaa caggatattt
    28081 aatcttggat gtataaaaaa tatattgttg accctaacat tacgtaatag tgtaatatga
    28141 aaatatagct tgaatatatt agtaggtatt gatggctgta aaattaaaat ttgaggtgtg
    28201 gatatgagaa cagtgaaaca agtttctgat ttaactggaa taagtgtgag ggcattacat
    28261 tattatgatg aaataggtct tttaaaacca aataaaatta cagatgcagg atatagactt
    28321 tatgatgatg aatctattaa aactcttcaa caaattttat tttttaagga gattgatatt
    28381 cctttaagag aggttaagga aataatgtca agccaatatt ttgataaggt tgaagctcta
    28441 aaaaatcaaa aaaaattact tattttaaaa cgaaagagac tggatgaatt gatagagctt
    28501 ataaatcaaa ctctaagagg agaaggaaat attgatttta aagagtttga tatgagcgag
    28561 tattttgatg ttttagaaga atttaaaaga gagcatagga ataaggtaat taaaatttat
    28621 ggtagtgtag aaaaatacaa tgaatatata gaaagagtta agtctaatga agagaaaatt
    28681 gctaaaatgg ctataaaaca atatggaact attgagaagt ttgctaaagc tataaaaaca
    28741 aattttagca gtgatatatt gaatttagga gaaaaatttg atagatataa aaatgattgt
    28801 ttaaaagaaa aacatccaaa attaaaagaa ttatatagaa agcttgtaga agatttaaat
    28861 aggaatcctt cttcaacaga ccttcaagaa atagcaaaag agataacaga tatatctaaa
    28921 aaagattatg aaattttctc tatggatact ggtgatgaca actggtatta tatggttcaa
    28981 aattatctag taaatcctat gtggatagaa gaagtagata aaaagtatgg aagtggagca
    29041 ggtaagttta ttggacaagt actaaagact tatctaagag atagaaaacc aaagataaat
    29101 acattgtatg aaaaacttgt agaagatttg agtagagatt gttcttcaag ggaagttcaa
    29161 agcattgttg aagaaataga caatgaaatg aaaagaagta atgaatttta taaaatagac
    29221 aatggtgaaa gatactttga ttatatgtca gagctttatt tacaagattc taactatata
    29281 aaagtaactg ataagaatta tggtgatggt gcatctaagt ttattggaga agcttttaag
    29341 atttattttg ataataataa ttgttgaaaa tttggaagta aaaaatatgc aagttttata
    29401 aaagcacaaa aataaggatg tagattagct ccatctatat ccttatttaa agttattaaa
    29461 atatatagtt tacatcaaac ttaacacttt caataatatt tcccaaatat gtttttatac
    29521 tttcaacttc ttctaaagat tttaatttat tttcagtata aattgctttg tccagaatat
    29581 taaaccttaa tcctatttca tcaaagtact catgatttaa aactttgtac caatggtttt
    29641 tttctttatt ccaactcgta gatattgaat cagcttcttt ttgagctttt tcccaatctt
    29701 cattttctat agatttttct aaaacagata tattgtcttt atatccttct gtaaaatcat
    29761 atagtttatt gttaacataa aatccaaata atacaaataa gatagtccat agtataacaa
    29821 atgttgtaga tttcaatatt aatcaccctt tttattttga ataaatattt tgtcattttc
    29881 atctaaaaca caaataagaa catctttaaa agtttctatg tgattagatt ttaaaatacc
    29941 cattaaccag ttagtatctt tttgagctat gtctagattt ttatttatta ttctaccatc
    30001 cagtataagt gggataggta aatgattaaa agctcttgga ggagtactat tgtagcttga
    30061 tgctggtaca acacttagat taccatcagt ctccaaaata gcatattgta catcttttag
    30121 gttaaagtat ccttgaatcc taagttgttc taataattca tctatactaa ttctttcttt
    30181 tttaagctct ttatatacaa tttttccttt atctattaat acagaaggtt tacctgataa
    30241 aaatgaactt aattttctac tttttaatga taagaatgaa attagagtct gcatgattac
    30301 aagtccagat attgctgcaa caccatttat gattggtata ttattatttt ccattgggac
    30361 agatgcaact tctgcaatta atagtgttat aactaaatca aaacagttca tttcagctat
    30421 ttcacctttt cccatgactc taagtgcaat tagcactgtt atgtataata taatacttct
    30481 tattaatact actgtcatat ctatcaatta ctcctttaaa aaatatttac acttagttag
    30541 tatatcctat ataaaaaatt taattcaaag tataaaaaac cttaaataat tggattcaac
    30601 tatttaaggt ttttttgata attttaatat taaatttttt atggattttc tgttactttt
    30661 atttatttta ataacagatt caacaaaact ctttttatct cctaatttta agataaaatc
    30721 aggatattct tcaaattcat tgagttttat taatttgaaa gaagaagata gatttttaaa
    30781 gttaataatt ttagagttat tcactaatac acttcttttt ttaaaataaa tttctttttt
    30841 acttatattt agtatagtta atatttgttt aagatatatt attatatctt ctggagttct
    30901 atcaaatttg agttcaaaat tttcatcttc aaagtaggga atataatata aaggtgtttt
    30961 gagagcaggt aatttattat ataattcttc aagaatatcg atatttttag gggagttaaa
    31021 gaaaaagcat ttacatacat tcattaaatc cacagcatct gaaagtgagt tatgtttaat
    31081 atctccttct acagaaaaaa tttttttcat attcagtaaa gatatttgct tagataagat
    31141 tctattattg tatgtaatat gttgagatat aaaaggttga atgtcaatca tcatattaaa
    31201 taactctaag catttacctg tatatttata tactctaaat gaagttagaa ggccagttat
    31261 atcaaaatca ccccaattat atattgtaac atcatcaaat ttacaaaacc atttataaaa
    31321 atcatccata acatataaaa gattaggagc attattgata tctagttggt tcaatttggt
    31381 taaattttta catttatttg aaagtatttt attgtatttt ggcttaacta aagagtaata
    31441 attatctatt gtattaaatt cgttatcaac taaaactcca ccaatagaaa ttaattccgc
    31501 accattatat tcttttggtt tatttttatt atcatctagt atattaaatt caaagtctat
    31561 aaataacttg tatttcataa atctaaagca catcctcagg taaattattt attgagccta
    31621 agcatcataa gaatcaatag atataatgac tctaaacatc aaaggttcat tacaactttt
    31681 atttatttca taatttaatt caaataaatc ttttaagata taatttataa gtattctttc
    31741 ccaacccatt tttaaattaa ctttagagtc tattaatata ttttctatct ttttaaatat
    31801 ttctatattt gctggtatta tactgagctc aatattactt ttaaacgggt tagactgtaa
    31861 atctgttata agtatatttt ttaattcctc tgtaagttca gaaattaaac tatcacctat
    31921 gtattttttt atgatttcct ctctaatttc ttttaaattt agcaatatta gtacctgcta
    31981 cttacatagt agcttttcct ttccttttaa tactattatt catttttgaa tcttatttag
    32041 atatatttta agattaaaag tctttagcta tataattttt tacccatttt taacttatat
    32101 taacatatta caggcttata tctccaccct gtttacattg aggatggagt atattgccta
    32161 ttttgataaa aatgataggt tgctatttgc ctattccttt ttctgataat ttttctaaca
    32221 tatctttggt cattttatct aaatcataac taaacttaaa gttccattct tttactgcac
    32281 tactactgtc tagagagtta ggccaagaat cagctatact ttgtcttaca gggtctacat
    32341 catattctat cacaaaatca ggaatatatt tttttataga atcagctatt tcctcaggag
    32401 aaaagctcat agcagtaata ttaaaagcat ttctatggat gagtttatca gctggagctt
    32461 cgattaaatc cactattgat tgaagtgcat caggcatata catcatatcc atttttgtac
    32521 cttctgctat gtaagattta tatctcttat tttttaatgc ctcataatat atatcaactg
    32581 cataatctgt agttcctcca ccaggaggcg taacataaga aataagacct ggaaatctaa
    32641 cacctctagt gtctactcca aattttgagt gataataatc acatagtaat tctccagaaa
    32701 ctttagtcac accatacata gtattaggtc tttgtaatgt atcttgagga gtcatatttt
    32761 ttggagaatt ttcaccaaaa gcagcaattg aactaggtgt aaaaaattta caatccaatt
    32821 ctttggctat ttcaagacca tttattaatc cattcatatt taagttccaa gcttctagag
    32881 gtttactttc agcaactgca gaaagtaaag atgctagatg aattatagta tctacatcat
    32941 atttttttgc aatttcaaaa aaacgattct tatctgtaac atctaatatc tcaaatatac
    33001 cagattcaca tactggatta ccttctttta ctctccttga actagcgatt acattttgtt
    33061 ctccatactc atttctaagc tttattgtta attctgaacc tatttgtcct aatgcacctg
    33121 ttataagtat ttttttcaat tttacaacct cctaagggtt taatttatgt agtactactt
    33181 atttttattt tagcaaatct tttgtttaaa tacaaagaat taaagataat aatatacgac
    33241 ttaattgaat gaagtgcagt aagtgcctaa aaatttaaag ctaatatata atggtatatt
    33301 gtataacaat aaaagagtag attaaattat tatatataga ttgtgtgact aagtcacaga
    33361 aaatagagtt aatttaatat ataataaaag catatcaagt aaagctttaa attaaagtaa
    33421 ctttataaat aaaaagtaat ataaattgat aaaattataa atttatttat agtgaatatg
    33481 ggttggattt tatagataca aaaatagtat atatgatatg tagaccatta gcaggtttaa
    33541 agtagcaaaa catataaaat aaaatttgaa aggaagtata aaaatgacaa gaccatcaat
    33601 atatcatagc caaggataca cttgtgcaga ggcattaata aagtcttata atgaggaaca
    33661 taacacagat ataccaatct caataggaag tggtatgggg gttggaatga atgttggaag
    33721 tgtttgtgga gctgtaaatg ctgctgttgt tataataggg tatttaaatg ggcgaaatag
    33781 taatttagat gaaaatatag caaggaagta ttcaagagag ctattgaata gagtaagaaa
    33841 taaatacagc tcagaaatat gtgtatctct taaaaaaaat aaagtaactt gtgaagaaat
    33901 aataaatttc acatatgatg ctctaaatga tatgctaaaa aatcaaaaat aattctaaga
    33961 aacaagtatt ttacattcga tagaatactt gtttttttat gatattttta ataagtatta
    34021 gtttattata atttttaaat caattttatt atattttaat tgaaacaatc tactttgaaa
    34081 attactaact gacaaaagaa tatgattata gtatagaaaa aatgtaaatt attt
//
LOCUS       DAYAKB010000037        33900 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.037, whole genome shotgun sequence.
ACCESSION   DAYAKB010000037 DAYAKB010000000
VERSION     DAYAKB010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.037"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            212..1405
                     /locus_tag="ACGI3L_002127"
     CDS             212..1405
                     /locus_tag="ACGI3L_002127"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HFG9197836.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1611..2729
                     /locus_tag="ACGI3L_002128"
     CDS             1611..2729
                     /locus_tag="ACGI3L_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HFG9197837.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            2860..3105
                     /locus_tag="ACGI3L_002129"
     CDS             2860..3105
                     /locus_tag="ACGI3L_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HFG9197838.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            3092..3838
                     /locus_tag="ACGI3L_002130"
     CDS             3092..3838
                     /locus_tag="ACGI3L_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9197839.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            4123..4998
                     /gene="hslO"
                     /locus_tag="ACGI3L_002131"
     CDS             4123..4998
                     /gene="hslO"
                     /locus_tag="ACGI3L_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFG9197840.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5389..6189
                     /locus_tag="ACGI3L_002132"
     CDS             5389..6189
                     /locus_tag="ACGI3L_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFG9197841.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6717..8957
                     /locus_tag="ACGI3L_002133"
     CDS             6717..8957
                     /locus_tag="ACGI3L_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9197842.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9371..10906
                     /locus_tag="ACGI3L_002134"
     CDS             9371..10906
                     /locus_tag="ACGI3L_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9197843.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVIIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            10922..11683
                     /locus_tag="ACGI3L_002135"
     CDS             10922..11683
                     /locus_tag="ACGI3L_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9197844.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            12021..12890
                     /locus_tag="ACGI3L_002136"
     CDS             12021..12890
                     /locus_tag="ACGI3L_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197845.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            13219..13470
                     /locus_tag="ACGI3L_002137"
     CDS             13219..13470
                     /locus_tag="ACGI3L_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HFG9197846.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            13582..14361
                     /locus_tag="ACGI3L_002138"
     CDS             13582..14361
                     /locus_tag="ACGI3L_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9197847.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFINYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(14496..15146)
                     /locus_tag="ACGI3L_002139"
     CDS             complement(14496..15146)
                     /locus_tag="ACGI3L_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197848.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(15143..15646)
                     /locus_tag="ACGI3L_002140"
     CDS             complement(15143..15646)
                     /locus_tag="ACGI3L_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9197849.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(15695..16210)
                     /locus_tag="ACGI3L_002141"
     CDS             complement(15695..16210)
                     /locus_tag="ACGI3L_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197850.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            16490..17017
                     /locus_tag="ACGI3L_002142"
     CDS             16490..17017
                     /locus_tag="ACGI3L_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9197851.1"
                     /translation="MHEQIDYCERKKIRTIDIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            17001..18404
                     /locus_tag="ACGI3L_002143"
     CDS             17001..18404
                     /locus_tag="ACGI3L_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9197852.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(18787..19098)
                     /locus_tag="ACGI3L_002144"
     CDS             complement(18787..19098)
                     /locus_tag="ACGI3L_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197853.1"
                     /translation="MKKIIKSFTSWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(19154..19747)
                     /locus_tag="ACGI3L_002145"
     CDS             complement(19154..19747)
                     /locus_tag="ACGI3L_002145"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9197854.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            20598..21248
                     /locus_tag="ACGI3L_002146"
     CDS             20598..21248
                     /locus_tag="ACGI3L_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFG9197855.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            21462..22133
                     /locus_tag="ACGI3L_002147"
     CDS             21462..22133
                     /locus_tag="ACGI3L_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197856.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFKLLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            22130..23260
                     /locus_tag="ACGI3L_002148"
     CDS             22130..23260
                     /locus_tag="ACGI3L_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9197857.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKLEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            23561..23683
                     /locus_tag="ACGI3L_002149"
     CDS             23561..23683
                     /locus_tag="ACGI3L_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197858.1"
                     /translation="MKWYTWLTIILIILLSIPLKIKFIKWWDRRQKNDKGGYDR"
     gene            23680..24525
                     /locus_tag="ACGI3L_002150"
     CDS             23680..24525
                     /locus_tag="ACGI3L_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197859.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            24525..25553
                     /locus_tag="ACGI3L_002151"
     CDS             24525..25553
                     /locus_tag="ACGI3L_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197860.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            25556..26569
                     /locus_tag="ACGI3L_002152"
     CDS             25556..26569
                     /locus_tag="ACGI3L_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197861.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLYYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLF
                     FSR"
     gene            complement(27086..28336)
                     /gene="cme"
                     /locus_tag="ACGI3L_002153"
     CDS             complement(27086..28336)
                     /gene="cme"
                     /locus_tag="ACGI3L_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HFG9197862.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(28422..29168)
                     /locus_tag="ACGI3L_002154"
     CDS             complement(28422..29168)
                     /locus_tag="ACGI3L_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9197863.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(29283..30305)
                     /locus_tag="ACGI3L_002155"
     CDS             complement(29283..30305)
                     /locus_tag="ACGI3L_002155"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFG9197864.1"
                     /translation="MNKNNCLDLIFEKVNPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTYSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGAGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(30305..32725)
                     /locus_tag="ACGI3L_002156"
     CDS             complement(30305..32725)
                     /locus_tag="ACGI3L_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFG9197865.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSYNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEVRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(32811..33731)
                     /locus_tag="ACGI3L_002157"
     CDS             complement(32811..33731)
                     /locus_tag="ACGI3L_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9197866.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
BASE COUNT        12538 a         3959 c         5717 g        11686 t
ORIGIN      
        1 gatatttata ttatattaat attagaaaaa ttttaaataa atgttttatt ctcaaaatat
       61 gcatattaat ttaataaaat ataccaaaat ggaaataaaa aataaatttt atgagaattt
      121 aataactaat aattaatata tttaggttat aataaatatg tgcgtaaaat ctaacaataa
      181 gcaataatac cgtaaattta ggaggaataa tatggatact ttaaaggaac tttttaaaat
      241 aggaagtgga ccttcaagtt ctcatactat gggaccacaa agagcagcag agagatttaa
      301 gaatgaaaac ccagatgcag aaagttttag agcaatatta tatggtagtt tggcagctac
      361 agggaaaggt cacttaactg actatataat tgaaaaaact atagcaccta aaaaagtcga
      421 aattgtttgg gaagaagata ttataaaaga ttttcaccca aatgggatga agtttgaagc
      481 tttagataaa gataaaaatg taacagctga atggactgta tattctgtag gtggagggac
      541 tatagcagaa gaaggtcaaa gaaacagtaa aagcaatagt atatatcact tagatactat
      601 ggatgagata gtaaaatggt gcaaagaaaa taataagact ttggtagatt ttgtgttgga
      661 atgtgaacca aaagacataa aagattatat aaaaactata aaagatgcta tgagaaaatc
      721 tattgatgat ggactaagta cagatgaaat aataccaggc aagttattat taaaaagaag
      781 agcaagtaca ttttataatg catataaaaa agataagagc ttctcaacac ttgtatatgc
      841 atatgcacta gcagcttcag agcaaaacgc ttctggtaat ataatagtta cagcaccaac
      901 ttgtggttct gctggagtaa taccaggaat attctttgca atgcaggatt tctataatta
      961 tgatgacgaa aaaataattg aagcactact tgtagctgga ataataggta atataataaa
     1021 aactaacgct tcaatatctg gagcagaggt agggtgtcaa ggtgaagttg gagccgcttg
     1081 ttctatggca gcagcagcag tagcatactt aaaaggtgga actatagacc atattgaata
     1141 tgcggcagaa atagcacttg aacatcattt aggaatgact tgtgaccctg tatatggata
     1201 tgttcaaatt ccatgtatag aaagaaatgc aatggcagct caaagagctt atgatgcagc
     1261 taattatgca ttattaactg atggctcaca ttctgtctcc ttagaccaag ttgttgaaac
     1321 aatgaaagaa actggtatag atatgatgga taagtacaaa gaaacagcta agggtggact
     1381 tgctaaacat ttcttctctt gctaaaaata aaattttcca ataataattc ctctgttttg
     1441 atttatgaaa caggggaatt attattaatg gtgaattatt taataatgca aaatattttt
     1501 atattcaatt tagcttttta tttttaatta gtataacatg ctatataata ttttaattat
     1561 aaagaaatat agaaatattt tttaataaat tagaaattgg aggagattac atgagagagg
     1621 catcatattt acaagaacaa ctttataaac ataggaagtc attaaatcct attgcagaga
     1681 ttgggagaaa agagtataag acttcaaaat atataagaga ttatcttgat aaattaggaa
     1741 ttgagtatga agtttattta gaaacaggta tagtaggtgt aatagaaggt aaaagaccta
     1801 aaaaagatat tgcttttaga gctgacatag atggtcttca tagtgaagaa ggggtaaaac
     1861 atttatgtgg tcatgatgga catgctacta tattacttgg attaattgag tatttaaatg
     1921 ataataaaga agacttaaat gataatatag tatttatatt ccaaccagca gaagaaggtc
     1981 ctgggggagc aaaagcttta atagatgaag gagtgcttag aaaatacaat attgatgaaa
     2041 tatatgggct tcatatatat ccagagttac cagaaggtta tgtaggtaca agagagggct
     2101 attttatggc tcaaatagga gatattgaca tagaaatagt gtctaaaagt ggacatgggg
     2161 ctatgccaca aaatggtatt gatggtatag tgatagcttc aaactttgta agctcacttc
     2221 aaactatagt gtctagaaat ataagcccaa tagacaatgc agtgttgact attggtagaa
     2281 ttgaaggggg agctagaaga aatataatag ctgaaaatat aaagatggaa ggtactatga
     2341 gatgtttcag cccagaagtg tatgagaaaa tgaagcttag agttagagaa cttgctagag
     2401 ggtttgaatt ggcttataac tgtaaggtta atataaatat tatagatgat tatattgctg
     2461 ttaaaaatga caaggatttg tatcaagagt ttgtagaggc tattggaagt gatactgttg
     2521 tagagttaga gccacttatg atatcagaag atttttctta ttatcaaaaa gaagttccag
     2581 gattattttt tatgttgggt tcaagaaacg aagaaaaagg atttgtaaat ggtcttcata
     2641 atataaactt taattttgat gaaaagatat gtgtaaatgc attgaatgtt tattcaaaat
     2701 tattaaaata caaagaagca atagattagg aagataagtt ataaagatta aaaagcataa
     2761 atacctaaat ttaaaaaaag tgtattaata aatacccctt acatatttgt ataaatttat
     2821 tttaattgac aaaaatacaa ataagaaggg gtgatttttt tgaaagaaaa agtacaaaga
     2881 gaaaagaaga taactaatgg caagaatact aaaatattga caaatgatga tataatgaaa
     2941 tatgagatag cctcagaact aggtcttatg gataaagttg gtgaacgtgg atgggcagga
     3001 cttacagcta aggaagcagg aagaattgga ggtatgctta catcacgcaa aaagaggctt
     3061 aaaaagattg tggaggagca gaataaaaag gatgagtcaa tatagtgatt ttgcgtttgt
     3121 atatgatgaa cttatgaatg aagttgatta taatggttgg gttaaatata tagaagatat
     3181 aatagatagt gaaggtgtaa aagtaaaaaa tatattggaa ttggcatgtg gcacgggtaa
     3241 tcttacaatt ccattgacta aaaaaaatta cgatatagct ggtatagata tatctgatga
     3301 gatgcttagt gtagcaagag aaaaggcaga aaaagaagga gtagaattag ttttacttca
     3361 acaagatata tcagagcttg attttgaaat atctgatttg gactgtgtac tttgtgcttg
     3421 tgatggattt aattatataa cttatgatga tgatttggaa aatgtatttt caaagacata
     3481 tgaattatta aagaaagatg gaatattcat atttgatata agttcttttt ataaattagc
     3541 caacatattg ggaaataaca tgtatggaga aaatagagaa gatatagcgt atatgtggca
     3601 aaattacttt gatgaagaag agaatctaat tgaaatggaa cttacattct ttattaaaga
     3661 tgaatgtgga aagtttgaaa gatttgaaga gatacaccaa caaagagcat atactgaaga
     3721 tgagatagtt gatatgcttg aaaaatctgg atttaaggat ataaaatatt atggggattt
     3781 tacatttgac aaacctagtg aagaaagtca aagaatcttc tttgtatgta aaaaataaga
     3841 tattcttgac tatataagat aattattaaa aataaccatg atataaaaat atataaaatg
     3901 cagttttata gattaaaagt aaagtgatga tattttatga tttttatttt ctaataatta
     3961 taaagtttta tagataaaaa ttaaaatata ataactattg cttagtaaaa ttaaaataaa
     4021 atgggttttg cccaaggtta agatagataa gtatttatag attaaaatta aggtagtaat
     4081 ataataaaaa taagacaatt aacgggacat ggaggaatat taatgagaga ttatgtacta
     4141 agagcgacat caggaaatgg tcaagttaga gcatttgtcg caactactag aaatacagta
     4201 gaagaagcta gaagattaca tgaaactaca aaagtagcaa cagcagcact tggaagaaca
     4261 ttaacagcca catctataat gggattaatg atgaaaaatg atagtgataa attgactgta
     4321 ataataaaag gtggaggtcc aattggaact attatcgcca catcagactc taagggaatg
     4381 gtaaaaggat atgtaggaaa tccacaagta gaggttgaag actatccaaa tggaaagtta
     4441 aatgtagcag cagcagtagg tacagaaggt gttgtaaaag ttataaaaga cttaggtctt
     4501 agagaaccat ataatgggac ttatccattg gtaagtggag aaattgcaga agactttact
     4561 tattattttg ctgtatcaga gcagactcca tcagtagtag ctttaggtgt tcttacaaaa
     4621 gaagatgaag tagagtttgc tggaggattt atagttcaat taatgccaga tgcagaagaa
     4681 gagactattg ctaagttaga ggaaaatgta gctaaattac cttctataac taacatgtta
     4741 aaagaaggaa aatcaccaga ggatatatta aatattgttt tggatggttt ggaacctaaa
     4801 atacttgata cctgtgaagt tgggtttatg tgtgaatgtt caaaagaaag agtaaaaact
     4861 gctttggttg caattggtaa aaaatcattg gctcaaataa tagaagaaga taaaaaagca
     4921 gaagttggtt gccagttctg taataagaag tatatgtata gtgaagaaga gttgcttgaa
     4981 attttaaagg aaatgtagac tataaaaata gttgtattga tataagtaat gttatagtaa
     5041 tatagtaaag tcgtattgat atagtaatta aagtataatt tattaataat agacatattt
     5101 atattaaaaa ataagtttaa taaattttta agcttaataa attttaagaa ttaagaagct
     5161 ttctggctgt aatgtttgca atgttgcagt tagaaggctt ttttatttta ttatagttcg
     5221 tgtcaaagat tgtatgaaac aataaaatat tgtaaaataa tttgtatatt tagacctgat
     5281 tgacacaaag gtttataaga tatttgagtt gattatacga aattctatga agtagtaacc
     5341 ctgtgacttt aatcatggga ggttcagaag aaggagaaaa ttttaaatat ggaaagtaaa
     5401 acgaagtaca taggaataag tatattaata ttattgatga tatttttaat tgcaaagaat
     5461 tttaacggaa aacttgaaat acctattcct gagagtaata gtagaaaatt taaatcagca
     5521 gcagtgtttt atcctcaaca tcaagatgat gaggttttat ggggaggaag tgccattgta
     5581 gatgctataa aacagtgtgg tgttgataat gtatatgtgg tattagtatc agatggttct
     5641 ggagttaacg ttttcaaagc taacacaaaa tttagaaatt taactaggaa gcaaaaggaa
     5701 gaacttagaa ataacgagtt taaatcagct ttgagagagc ttggagtgaa acctcaaaat
     5761 gtgattatac ttgcagatat agataaaaag gaaggcacac attatgaatt aatggaaaag
     5821 actatattgg attttgaaca taagtttaaa ggcaatgtga cccatatagc ccatcactat
     5881 aagtatgatg accatataat gcatagaaag aatggggaag ttttaaagaa acttaaacgt
     5941 gaaggtaaga taaaagatga cttgtatttt gttaagccaa aatatgtaaa gtatatacca
     6001 agaaatgaaa gagctatcta taaagcaatg gattttgatg actacaataa ggttaagagt
     6061 gcttgttatg aatataaggt tgtaaattca aagcgtaaaa tgtatggtat aggatatatt
     6121 tcggcacata gttattttga acatcttcta aatgaccctg aacttacgtc tgtattaagt
     6181 gaagattaat ttcttataag tagtaagtta tgtttgataa gttgattgga attttctata
     6241 gttttgaagg tattggaaat ttagttttat ttaaagattt aaagatagag gtttttagtg
     6301 tttaaaattt taaagttaag ttgaataatt gtatagaatt atttgtgaaa gaagaaacag
     6361 tgtaaaacat agtatcttat ttatggtttt aaaatcatag gcaagatact ttttttatgt
     6421 aactaatacc attttgagat tattaactta agaattttat ataatttaac actcatatat
     6481 aatgatgata tttaggtaga atagatgtaa ttacgcttaa ataaaataac tgtatttttt
     6541 ataaaaatcc aaaccctaca ctatactacc agataaaatc tacatgctat aatttgacct
     6601 gtgtttataa aaaaaggagt aatctaataa aatagtattt cacttatgta taactaacaa
     6661 ctattattac gattttctct aaataattta aagaaaaata atgcaggagg taaaatatga
     6721 acaatgaatt tataatttta aaaggttgca aagagaacaa tttgaacaat atttccttaa
     6781 aaataccaaa aagaaaaata accatattca caggggtgtc gggttctgga aagtcatcta
     6841 ttgtatttga gacaattgca aaagaatcac aacgccaact aaatgaaagg tttagtacat
     6901 ttgtaagaag ttttttacct aagtatggag aggttaaagc tgattgtata gaaaatttgt
     6961 caacaccaat tatcatagac caaagtagac ttggtggaaa ttcaaggtca actctaggta
     7021 ctattacaga tgtaaattcc tttttaagag ctttatattc aaggtttggt agtgagtata
     7081 taggtaatgc caatatgttt tcttttaata atattgatgg tatgtgccca cactgtcatg
     7141 ggcttggaaa aaagctagtt cctaatatga accaaattct tgatatgaat aaatcattaa
     7201 atgaaggtgc tatattgctt tcagggtttg gagtgggttc ttggcattgg aatatattcg
     7261 ctgaatcagg attttttgat attaataaga ggatatgtga ttattcagaa gtagaattgg
     7321 aaaagttttt gcatggtaaa gcagaaaaga ttaagataga aaatgctggt caaactaaca
     7381 tgacatatga gggattaatg gttaaattta atcgcctata cttaagtaga gagggagaaa
     7441 tatctgaagc tactaagaaa aaattgagta aacttcttat agaagataga tgtcctatat
     7501 gtgatggaag aagacttaat gaaagagtat ataggtcttt aattaatggt tataatatag
     7561 cagatttaac tagtatgcaa attgatgaat tggctgaagt tattaaaagt atagatgagc
     7621 cagaagcaca acctttaatt aaaggaataa tagaaaagtt aaacagtatc atagatatag
     7681 gtcttggata tttaacacta gatagagaga catcttctct atcaggaggg gaatctcagc
     7741 gtataaagat ggttaagtat ttaaatagta atcttgttga tttaatgtat atttttgatg
     7801 aaccaagtgt aggacttcat ccaaaagatg tgtataaatt aaataatctt ttaaaaaaat
     7861 tgcgtgataa agggaataca attatagttg ttgaacatga cccagatgtt attaagattg
     7921 cagaccatat tgtagatgta ggaccaaagg caggtaagta tggtggagaa gttgtgtatg
     7981 aaggcagtta tgaaaatcta cttacaagtg gtactttgac agggaatgct ttaagtaaat
     8041 ttcttcctat taaagaaagt gtaagagaac atagtggata tttagaagtt aaaaattgta
     8101 ataaaaacaa tttaaaaaat gtatctatta agatacctaa aggtgtattg actttagtta
     8161 ctggagtagc aggagcaggt aaaagtacat tgattaagga tgaattttta aagcaaaatc
     8221 ctagtgctgt acttatagac caaagccctg tttcagcaaa ttcaaggtcg agtttggcaa
     8281 catatagtgg aattatgaac aacataagaa gcatattttc aaaaacaaat ggcgtaaatg
     8341 cttctttatt cagttcaaat tcagaaggag cttgtgataa ctgtaagggt tctggaatag
     8401 tagaaatgaa tcttgctttt atggagagta taaagagtac ctgcaatatt tgtgaaggta
     8461 aaaaatttaa aaaagaagtt ttagaatata ggtttcaagg gaagaatata attgaagttc
     8521 ttgaaatgtc tgttttagag gcaattgagt tttttaattt aaaacagatt aaaacgaaat
     8581 tacaatgtat tgaaaaaatg ggtattggat accttacttt aggacaaact cttgatactt
     8641 tgtctggagg agagtgtcaa agattaaagc ttgctagtga attaaataag gaaagttcag
     8701 tgtatatatt agatgaacca acaacaggtc ttcatatggc tgatattgag aattttataa
     8761 gtataattga agagattgta gataatggaa atacggtcat aataattgaa cacaatatag
     8821 atgtaattaa aagagctgat tggattattg agctgggacc tgaaggagga acaaaaggcg
     8881 ggagagtaat atttgaaggt attccaaaac aattatgtaa caataaaata tcattaacag
     8941 caaaatatat agtataataa ataaaatata ataaaattat aatgatattt taataaatat
     9001 aatgggtata taaaatgata attaaactta acagtaataa ataatgtgag aaatattcaa
     9061 atttaattaa ataaagtgtc agaaatttgt ttaaatttta gtattttaac ggttctgacc
     9121 ttttttctta tttttatgga gaatatcgag gatggagtct ctaatagtta cttttttgtg
     9181 tctacttgca agtttgatta aaaaatggct atacacactt gtgacttcag tcatgggagg
     9241 ttcagattat aatcttaata tataatttgt gaaataattt gatgacgatt tgctgatgta
     9301 taaacaataa agattaacta cattaaaatt taaatcttgt taagtaaaac ttataaaagg
     9361 agagagatgg atgataaatg atattctaac cttattatct gaaagaagtg atttttttat
     9421 aaagctatcc atagaacatt tgatgatttc tattatttct ataataattg cgattgtttt
     9481 gggtggtata attggtatta ttgtaagtga atttcataat tcttctaaac ctatattggg
     9541 aactatcaat tttctataca ccattccatc tatttctatg ctaggatttc tgataccatt
     9601 ttccggaatt ggaaatacta ctgctgttat tgcacttacc atttatgcat tattgccaat
     9661 ggttagaaat acatatactg gaattactaa tgtggataaa aatattcttg aagcagctag
     9721 gggaatggga agtacagatt ttcagatatt gtataaaata aaacttccgt tagccctacc
     9781 tgttattatg tctggtatta gaaatatggt gattatgaca attgcattag ctggtatcgc
     9841 ttcatttata ggtgctggag gcctaggtgt agccatatat agaggaatca cgacaaataa
     9901 cacaataatg acaattactg gaagtatact tattgctcta ttagctttaa tatttgattt
     9961 tattttaggg ctggtagaaa aattttttca acgaaaaaga aaaaagaaaa ataggaaaaa
    10021 agtttttgcc attctaggaa gccttattct tatagtaatt atctttacgt cttatttatt
    10081 taatccttca aagactcaaa ctattcatat tgctactaaa cctatgactg aacaatatat
    10141 tcttggtgag atgttggata ttttaattga aaaaaacaca ggtctaaacg tggaaattac
    10201 acaaggtgta ggagggggaa catctaatat ccagccagct atggagaatg gagaatttga
    10261 catttatcca gagtatacag gtacaggctg gaatatggta cttaagaaaa atgaattata
    10321 tactgaaagt atgtttagta aactacagtc ggaatacaaa actaaactta aaatgcaatg
    10381 gactggtatg tatggttttt ctaatagcta tgcattagca gttagaaaag aagttgcaga
    10441 taaatacaat ttaaaaaata taacggactt aaaagatgta tcttctaaat tgacatttgg
    10501 agctgaatat gacttttatg agagagagga tggatatact ccattgtgta atacatatgg
    10561 actgaacttt aaagatacag ttgatttaga tattggatta aaataccaag ctatcaatga
    10621 aggtaagatt gacgtaatgc ctatatttac aactgatggt cagtatagtg tttcagatgt
    10681 tgtagttcta aaagatgata aaaatttcta cccatcttat caatgtggaa atgttgttcg
    10741 tttggaagta ttagaggaaa atccagaact atcaaaggta tttaagatgg ttggagatat
    10801 tttgactgat aaagaaatgg ctaaaatgaa ttatgacgta gaaaacaaca atttagaacc
    10861 tagagaagtt gctcgtgagt ttctgaataa gaaaggtctt ttataaattg gaggaaatat
    10921 aatgacacct attatacaat ttaaaaatat taaaaaacaa tataatgata aaactataat
    10981 agataatctt aatttagata tagaaaaagg agagtttttg actgtaattg gttcgtctgg
    11041 ttctggtaag acaacactct taaaaatgat taatggtctg attttgccag atggaggaaa
    11101 tattttgata aaccaaacag atatcaaaaa cgaggactta attaaattaa gaagaagaat
    11161 aggatattgt gtacagggaa gtgttctttt tcctcatatg actgttgaag aaaatatttc
    11221 atatgtacca aatctcctaa gtaaaaagaa taaattagaa gtaaaaagtg ctgtaaacaa
    11281 gtggatggaa atagtgggat tgccaaatga tatgaaagtg cgttacccat cagaattgtc
    11341 aggtggtcag caacaacgtg tagggattgc aagagcttta gcttcttctc cagaaatttt
    11401 attaatggat gaaccttttg gtgcagttga tgagattaca cgaaagcaat tacaaaaaga
    11461 gataaaagaa attcataaaa aaacaggagt tacgattatc tttattacgc atgatattta
    11521 tgaagctttg attttgggaa caaagacttt ggtattaaat catggagttg ttcaacagta
    11581 tgatactcct gagaatattt taaatactcc tgctaaccaa tttgtagacc agttattgaa
    11641 tataagaaaa tctataatag atgatgataa tttaaaagaa taaatttaaa tttaaaatca
    11701 aattgttgtg ataaaaacta ttgatttaga gctaacttca agttgtatac ttgaagtgga
    11761 aaagttagat taaggtatag aagggcattt agcagttggc tgtagacgag gtaactgctg
    11821 aaggtgcttt caataaatgg ctagaacctg tatctgttga agattataat aaattgaaat
    11881 aagaagctca atatacagag tagataggca cttcaaatag aagtgtcttt tgtgtgccat
    11941 aaaataaatc aaaatattag caaagaatgt gaaaaacaaa ataaaataat atgctatctt
    12001 taaaatagga gggatgctat atggataaca atttgattac cattgaaaaa actttagatt
    12061 atatagaaaa acatctttta gatgagatgt tagatttaaa tgtaatttct aaagagatag
    12121 gctattcaaa ataccattta catagaatgt ttacatcagt tgtcggattt agtgtacata
    12181 attatataca aagacgtaga cttactgaag cagcgagaat gctaattttt acagaaaaac
    12241 caattattga gattgcttta atctcggggt atgatacaca acgctctttt tcaagagggt
    12301 ttaaaaaaat gtttaaacgt agtcctaatt tttttagaag acatcaagat tttttaccac
    12361 tacaattaaa atttgatatt cataatagaa aaaaattacg tggagatatg gttttagatg
    12421 ttaaaaaagt taattgtgca gatataaata ttgttggcta ttctggtaaa gtaagaaaag
    12481 gatttcatat tattggaaaa tgctggaggg atttgcataa aaataaagag atgatagaaa
    12541 ataaggtaga tttaggtttt ttaattggag ttagtgatta tagcaatttt aaagagattg
    12601 agaatactcc tacatttaca tacattgcag gtgctcaagt agctactttt ggcaaattac
    12661 ctaatggaat ggaaaaattc gtattaccga aaagtaatta tattgttttt acttttattg
    12721 ggaaaaatga ggatagtatg caaaatgttg tagaatatat ctatcaagaa tggttcccta
    12781 attcaagttg ccagtttaat gaaaataatt tatatgactt tgtaaaatat ggagaaaaaa
    12841 ctgatgagaa tggtttgagt gaaattcagt tttgggttcc aatcatttaa aagaaggtat
    12901 tatgtataaa gtagatggat ttatataggc aaagttttac agcagtatgt atttataaat
    12961 aatttatagt ttgtaggaaa gaaataattt tactataaga ttatgataaa atacacaata
    13021 ctatgacaaa atagtgttaa ataatagatt taattttgca taggaaaagt tctataatgg
    13081 tgtgtattca taaataattt ataatctgta ggaaagaaat agttttacta taagattatg
    13141 ataaaataca caatactatg ataaaatagt actaaataat agatttaatt ttgcaaagga
    13201 taaggtgttt taataaaaat gaatgtagaa aacgaattac ttaaaaacct agatagattg
    13261 catacaacag agttaggcgt tgtaagaatt aagaaaaatc tttctttgga gacaaatgat
    13321 gtagtgaact ggtgtaaaac taaaatagaa tctccaaatg ccattattaa tagaaaggga
    13381 aaaaactggt atataagtgt atatgattgt attataacag taaacgctca cagttataca
    13441 attattacag ctcataaaga aaagaaatga attgcaaaat acaaaggtca aaagcatttt
    13501 ccactgtttg tagtacctat gaagaagtat ataaaataat attacttttg aataataatt
    13561 taaattttgg aggttgaaaa aatgaatgat actgtaaaag aaaaattggc agagtcacta
    13621 acttctgata ctactgatat tttaccttat ttgccttatt tattacaaga tttttgggaa
    13681 ttaggaagtt caccagaaca aatgttacaa ttatttagaa agcatatacc ttttaatgag
    13741 gatacaaaag ttttggattt agcttgtgga aaaggtgctg tatctgtgaa gcttgcaaaa
    13801 gagttgaata tacatatcaa aggtattgat ttgatacctg aatttattaa ttatgctaga
    13861 agaaaggcta ttgaatataa ggttgatgct ttgtgtgatt ttgaaatgaa tgatgctaat
    13921 agttctgtaa aaattgagca tgattatgat tgtgtgattt ttggagctgt aggggatatt
    13981 ttaggtaatt ataaagaaac tataagtaag ctattaccta caataaaaag taaggggttc
    14041 attttaattg atgatgcata tgtagtagat aaatctacaa atgaacagct taattttgag
    14101 agggtgtatc ccacttacaa tgagtggtgt atattgttca aagaattagg tctgaagcta
    14161 attgaatgta taccatgttt agaacttgaa aatgatgttg aagaggaaat gaattggatt
    14221 ataactcgtg caaatgagct aattaaaaaa tatccttctc aaaaagatat gtttgaacaa
    14281 tatgttatta gccaaaaaaa tgaatatact gatttacagc aggaccttgt tggagcaact
    14341 tggattttac aaaaagaata agataaatat tagactagat aatcaatgtt atagtgaatt
    14401 atcccatgtc tagtgaatat aaataacata aaaaaccgtc aagatgaata gtttattcgt
    14461 gcttgacggt ttttagtatt tgttgaagta aaattttatt tctttagtat atcactttta
    14521 gtcaatccat ttgatttagc ttgagtattc cattgatgat tccccataag tttatatagg
    14581 aatctaggga agttaggtga aataaaaata gtacttttgt tggaatcatc tatatgtata
    14641 ttatcactaa gtatattttt tgaaagttct tttaatgcaa ttcctaaatc ttttttaggt
    14701 cctttaccca aaggtacgga ttctagtgaa ccaaacatct ccccagctcc aattccaata
    14761 ccttgaaccc atgtaaagtt gattttttta caccaatgct ctatcatttg aattgccaaa
    14821 tgattatgtt caccttcatt gaatccacag ttaactattg catacactgg aataggtttt
    14881 ttattttgtg tttttaaaaa tttttcacat ttctctaaaa aatgaagtaa atgagatgga
    14941 ataccatcta cataaagagg agatgcgatt attaatctat cacaattaag tatggcatta
    15001 agagcgtcag gatacttaga tgtgctatct actttaaatg taaaaacttt attatcattt
    15061 tgaataagtt gttttaattc agataaaaaa tactgtgaat tatttttatt tacttttgga
    15121 ctaccattta tcattactat attcatatgg attcacctct tatatcttgt atattttcat
    15181 agaaacaaac agagtgttct tttatattga aatttatagc atttccattt actaatttcg
    15241 tagcagtttc tttttcagct tctgtaatac aatctccata gaatatagct tttaaattta
    15301 tctgtttatc atatctgctt ttatgacgca tcatattatc ttttattaca aagtatggaa
    15361 gaatataatt aatgctttta tcaagtacgt ttttgacaaa agggctaaac cctccgtaac
    15421 agcatctgct tattataata attccatcag agtcatttat aagtttaccc atgttgctgt
    15481 aataatcttt tacaacacat tcagaaggag ttttaatcca gcaaccaaaa caaccaatac
    15541 atttgtggat ttcttttgtg tttggaagta tttttatatt gtcatcaagt ttgggtaata
    15601 acttttctaa ttctttgtca gttaaatcat gtattaaaag cctcataaag tccatctcct
    15661 tttattatgt atgtttactt ctaaaaatta tatcttatag atttttcagt aaatctttac
    15721 accaattaat aacaaaatta taatagtcaa ctccataaat cattgttgca tacatatatg
    15781 tatattggtc aacgcaatga ttttcttctg catcattttt ttgtttactt aatttattta
    15841 gaagtaattc tacttcagtt attaacattt ttaagtttgt ttcaattatt tctttgggta
    15901 gatacttgta aaagaatata ttaacaaggt ggtcttgctt tgttttagaa aaatttatag
    15961 gtttctttaa ccattcaaga aatacttctt taccagtatt agttatggaa tataattttt
    16021 ttaatttgct accatctata acttcgtgat agtgtatata tccttttgtt tctaatcttt
    16081 taagtgcagg atagatactt ccaaagctgg cgtcaaaaaa gtacgaggta ctttctgaca
    16141 ttatttgttt taagtcgtat ccacttaatt ctttttccat taaaaatcct aaaataatgt
    16201 attctaacat attacctcct ggtatcaatt agatatatat cgattcgata tatttattat
    16261 tacagataat aaatcttacg tcaagatgct ttttaagata agctaaaaag aattaggagt
    16321 tattgataaa tatgcaaaaa aattaatata aaaggtaatt aaatatcaat gaagatttaa
    16381 aaatagttaa atcaaagtaa gagtctaata tataaaattt atagtaactt tatggtttaa
    16441 atataaactt gcgtgctatt gacaaagtat aaaattagca gtaaaataat tgcatgagca
    16501 aatagattat tgcgaacgca aaaaaataag gacaatagat attaaaggag agaatatgag
    16561 agagctatta aaatgggttt ccattataaa tagatacaat acaaattata ttgacaggaa
    16621 attggcggat attggaatca ataatagcca atatttttat gtattacaca tatgtaataa
    16681 tccaggtatt acacaggaca ctatatttga gaaaattctt gtgaatccta gtaatataac
    16741 aagagctttg gcaaatttag aaaaagaagg ctttataaca agagaaccag gtgtaaagga
    16801 taaaagaaca tggcatttat atcctacaga aaaatcttta ggatgttatg atgaaatact
    16861 aaaaataaca aatgggtatg ttgaggagtt gttgagttca tttgagaaag aagagcaaga
    16921 gttgtttatg tcaatgttaa agaaagttgc atttttggct attgatatga atgaagaagc
    16981 aaaattggag gcgaaggaaa atggaagaaa aatataagga gccattggaa tatgaaaagg
    17041 tttcaaagtt attaactaag tacgcaattc ctagtattat agcaatgtta gtaagtgctt
    17101 tatataacat tgttgaccaa atatttattg ggcaaggtgt tggtgtattg ggtaatgctg
    17161 ctacaaatgt cacttttcca ctaacaacaa tatgtactgc aattgcatta ttgttaggaa
    17221 ttggaggagc gtctaagtgt tcattggaat taggtgctaa aaattcagaa aaagctacaa
    17281 aagcagcagg aaattctata tgcttgatgg ctgtttttgg aataagttta tttatagtag
    17341 tatcaatatt tttaacacca ctattaaaat tctttggctc tacatcagaa atactacctt
    17401 atgcacacac atatacaaaa attacatcaa ttggattacc atttcttata atgtccactg
    17461 gaatgagtaa gttgatactt gcagatggga gaccaaaagc ttctatgttt tgtatgttaa
    17521 taggagcagt tattaataca attttgaatc cattattcat ttttgttttt aatatgggaa
    17581 ttgctgggtc tgctttagca actgttattg ggcaacttat atcttttgga ataagtgttc
    17641 attatataaa gaattttcaa catattaaat tacataagaa aagttttaaa ttagatagta
    17701 taatttataa acatatattt gcgctaggtt caagctcatg ttttaatcaa ttagcaatga
    17761 ctgtaacaca gatagttatg aataatacat tggcatatta tggggctagg tcagtttatg
    17821 gaagtgagat tccacttgct tgtgtcggta tcattattaa agtaaatatg atttttatat
    17881 ctataattat tggtatatca caaggtatgc aaccaattat agggtataat tatggggctg
    17941 aaaagtataa tcgtgtaaaa gaagcatata agtttgcagt gggaagtgca actattatat
    18001 ctgttattgc attcttatgt ttccaattct tcccaagaca aattacgtct atatttggta
    18061 acggaaatga gacttatttt atatttgcag aacattattt tagaactttc ttgttcttaa
    18121 catttataaa tggtgttcaa atagtatcat caactttctt tacatcaatt gggaaatcag
    18181 tgttgggact ttttacttct ttgactcgtc aaattttatt tttaattcca ttgatagtaa
    18241 ttttaccaat gtttatggga attgatggag taatgtttgc aggaccaata gcagatgcag
    18301 cagcggcaat ggtatgtata tactttgcag ttcatgaaat gaaatcattg actataaagc
    18361 aaaataattt gatgagtaac cataataaga ttgcagaggt ataagacaat atttaagaag
    18421 tatagaaaat taatttaaaa aatataataa attaatttag gaagtgtaga aaattaatct
    18481 aaagaagtat aataaactaa tttaggaagt atagaaaatt aatctaaaga agtgtaataa
    18541 actaatttag gaagtataga aaattaattt aaagaagtat aataaactaa tttaagaaat
    18601 atagaaaatt aatttaaaga aatacaatac attaattttt aagtaacatt aaattaatgt
    18661 aagtaaaata atgttcatat gaatatttaa aggtgcattt tctgaagcta agtatatgtt
    18721 gtagagtgtt atgtctctct atcctgtgaa gtttaatagc tcaagaaaat gcactattta
    18781 tgatgattat tttgttttat ttccaatttt ggaaataact attctaatta aatctaaaat
    18841 tataccataa ataagaaaag aaagtataga tgctatgtac caataaatcg aaattgaccc
    18901 tgtaattgtt ctacatggga tttgcatacc tgaatccata aaaacaaaaa aactatcaac
    18961 tctggaaata atagacaaaa taggatttaa acctattaga acaatacttt ttgagtcttg
    19021 accaatttga tgcatataaa tctcaaataa tgcaattaaa aaaaaccaag atgtaaaaga
    19081 tttaataatt tttttcatca aaatacctca cataatataa attctgtttg cactatttgc
    19141 ttactacaac tatttatctc cattcagtca catcacttaa ttgtaatcta ggtcttcttg
    19201 atggttcttc atcaggataa cctaaagata ttgctgccac taattgacta tctgtattta
    19261 accattcaca taattcacga tatgcaaagt atacatcaca aatccaaaga ctacctagac
    19321 ctaattccac agctgtaagc gacatattct gaattgcagc tccaattgat tgcatatttg
    19381 ccatttcata gaatcgttct tcaggggata gcttttctaa aggtgattta cctaatatat
    19441 ttaaaataaa aattgttact ggagcttgtt tcatgatttc aactgtgtaa tttgcaccag
    19501 cgatatgttg acgacttcct ggaagaagcc cattatcatt aatttcattt tgaatacctt
    19561 tgctcatggc tttaagcata gattcttttt ccttttcagt gatgacaaca aaacgccatg
    19621 gttgcctgtt tttagatgaa ggtgcattta ttccagcttc aattattttc tctatagttt
    19681 catgtgaaat gctttgattt ttatattttc tgatacttcg tctttttgat atagaatcac
    19741 ttatcatttt aagtaacctc cgtttatttt ttggaaaaat ctatttaatt tttattttct
    19801 attttaatta ttttagcatt aatcagaaaa aaagtcattg attttagtat acaattatta
    19861 atgattatat taagaattgt atcaaaaagt atgtgattat actaagggat tatattaaac
    19921 attatattta aaattgtatg aaaggttgta tttaatatta tattgagaga tatatatatt
    19981 aggatttata tatattcaga tttattatta tattgagtct tatattaaat taaggactat
    20041 aatttgaaaa taagctataa aaactcaata ttgttttgtt caaagataaa aaaagaatac
    20101 tttaggtgat ttttattaaa aattaagagt gataagatta tatactttat aaatgtaaat
    20161 atgacggata aaaatgataa atataataat atatatattt acattaggag ttttctatac
    20221 tataattatt taaaactaaa tataaatgtt ggaattattt aggacttgaa attgtctaaa
    20281 aataaatata agtgatgaag aggtgatgtg atgagattag atatggatag tatgttatat
    20341 gtactaattt atatgacatt attggtatct atcattggaa gtatatttta tttttgtaaa
    20401 gacctcttaa atcataaaat taagtatgtt ttaataagag acatatttgt aaatagaatt
    20461 acatattctg aagaacggtt gcctaaacag tatatagttt ttcagaaata tgatatttgg
    20521 aggtattgta gtttgtttta atttgaaatg aatctattat aaattctaaa gtttaaaaat
    20581 aaaaaggaga gaataaaatg gatttcattt caagtatatt gcaaggatta ttaagtatat
    20641 tatttaattt tacaggtgat tttggaattt ctattgtact tataacttta atagttaaat
    20701 tagtacttat gccactatca ttaaaacaaa gattttctgt aaaaaaacag caagaattag
    20761 ctgaaaaaat ggaacatata aaagaaaagt ataagaatga tactaaagaa ttggaaaagc
    20821 aaatacaagt aagttctgta gaaagtatga agagtatgct gggatgtctt atagttttgg
    20881 ttcaaatgcc agtagtatat gctttatatc atgtatgttt agatatgaca aaggaattta
    20941 caacaattat aattccatgg attgctaatt taggtacatt tgataatttg tttatattac
    21001 cttgtatata tacattaatt atgttagctt caaatttagt gaattatata ccatatttaa
    21061 aaataaattc tcaagtaaag tttaacaaac aaatggctgt ggtgactacc ataacaagtc
    21121 ttatactaac tgttagaact ccagtagcca taggtctgta ctttataaca agtgcaattt
    21181 attcattaat tgaagatatt tgttttagaa tatattttaa tcgaaaaaat agaatagtga
    21241 caaaataata taattattat tagaaatatt ttagcctgct aacatagaaa aagttagtag
    21301 gctattttta tctatgatat caattccatt aagaatagtc taaaaaatac tatcaaaatg
    21361 ctataaaaaa tactatcaaa atactataaa aaaatagttg aaaaataaat aaattaatat
    21421 aaactaaaat aaagcctaca aaaaagaggt gataaataga aatggctaaa atactaattg
    21481 tagaagatga aaaaaggatg caaagtatta ttgtagaata tatgcaaaag ggaggatata
    21541 cttgtataac tgctgatgat ggagtcgagg cacttacaat attaaagagc aacaatatag
    21601 atttaatgat attggatatt atgatgccgt atttagatgg attttcagtg tgtagagttt
    21661 cacgtgaaat gactaatata cctattatta tattgacagc taaaggtgaa gaggaggaca
    21721 aattaaaggg ttatgaatat ggcgcagatg attatataac aaaaccattt agccccaaag
    21781 tacttttagc aaaagttaat gccttgttac gtagatacac tactgatatt cccaaaaatt
    21841 cattgagttt aggaaagatt tttattatgg tagcatcaag gcaagtgtat gtagaagata
    21901 aattgattga tttaacatat aaagaattta aattattgcg tttatttatg gaaaacccta
    21961 atcaagtttt ttccagagag aaacttttaa attgtatatg gggatatgat tttgaaggaa
    22021 acacacgaac tgtagataca catataaaaa ccttacgcaa aaagcttggt agtgaaggac
    22081 accatatagt tacattaatt cgttcaggat ataagtttga ggttaaggaa tgaatagttt
    22141 aagaaagatt atagaaaaac tgaaaaatgt agatatttca aattggatta aacaaaattt
    22201 tggactatat tcagttagaa aaaaagtgtt tttactttct aaattatcag gagcgttaat
    22261 tatattattt tatctggttg ttgaagaatt ttcgataaac tctaaattag aattttggat
    22321 ttggtttata atactggtta tatttattat gagtattgat ttcttattgg gaaaatttat
    22381 ttcagaacca atcacatcta taaataaatc tgcaaaaagt atgtcccaac ttgatttttc
    22441 taatccatgt actgtaaata ctaatgatga atttggagaa ctttctagga gcctgaatac
    22501 aatgtctaca aatctacaac aggcattatc agacctagaa agtgcaaata ttcaacttga
    22561 aaaggatgta aataaggaaa gaatgctatt ggaacaaaga aaggagttgg tagatacaat
    22621 ttcacatgaa atgaagactc cacttggcat tatacgtgcg tatacagagg ggcttatgga
    22681 tgaagttgat gaagaaaaaa agaaaaatta tatgaatgtt ataatagaag aaactgatag
    22741 aatgaacaat atgattgtat cattattaga cttatctgca ttggaagcag gagtttctaa
    22801 acttaaccca gagcgttttg attttataga gtttgttgaa actgtggcag gtcgtctttt
    22861 aattgatata ccagatgcca atttttattt tacatatgat ttgccagagt atgaagtttt
    22921 tgtagtggca gataaaatga gaatggaaca agtagtagag aatctagtta ttaatgcaaa
    22981 gaagcatgtt gtatataatg gtaatttaga tttatcgatt acatgtgaaa atggcttgct
    23041 tttatttgaa atttataatg atggtaggtt tatagagcaa gatgagattt caaagatttg
    23101 gtctaagttt tatcgtagtg ttcaatctca gcgtacagga ggttcaggtc tagggcttgc
    23161 aattgtttca caaatactta caatgcaagg gttagaatat ggagtgaata atcgtgatag
    23221 aggagtagag ttttatttta tgattccaat tgatgaataa tttagtatta atttataaat
    23281 tataagtatc tgatgtaaaa tatttttctt tgtatatgta agcatttaaa gagaataaaa
    23341 taaaaaaact taatgaaaaa agcttaatga aaaagtctaa taaaaagctt aatgaaaagt
    23401 cttgtttttc tgatgaaaac aagatttttt attaagcttt ttattatttc acttcgattt
    23461 cacaagagag acactctgat ttcaccaaat agaaataaaa taggttaaat aaattaaaaa
    23521 atagaagcgt aattaaataa ggttacaagg gggagtactt atgaaatggt atacatggtt
    23581 gactattata ttgataatat tgctttctat tccgcttaaa attaaattta taaaatggtg
    23641 ggatagacga caaaaaaatg ataaaggagg ttatgataga tgataaaagt aggagagtta
    23701 aaattttctt atggaaaaga taaacagata ttgcatggac ttaattttga agtaaaagaa
    23761 ggagaaatct ttggattcct tggacctaat ggttcaggaa aatccacaac acagaaaatc
    23821 ttaaatggtg ttttaaaagg ttacaatggt cacgtatccc tttttggtaa ggaagttaaa
    23881 gcatacacag aatctttata tcaaaagatt ggtgttttat ttgaatttcc ttatttatat
    23941 accaatttaa gtgcaattga taatttagaa tatttttcgt ctttttatcc taaaaatcaa
    24001 aggagagata tatatgaact cttagatttg ttagagttta agaaagagtt tataaataag
    24061 cctgtatcat cctactcaaa aggtatgaag caacgtatta gtatggcaag agcattggta
    24121 agtaatccaa agttgttatt tttagatgag cctactagtg gacttgaccc atctggagct
    24181 gtactatttc gtaagattat tgaagaagaa cgaaaaaaag gaacaactat ctttttgact
    24241 actcataata tgctagatgc agatttaatg tgtaacaatg tggcttttat tgcagatgga
    24301 aagattatgg taatagataa acccaaaaat ttaaaaatga aaaatagcaa taataaagtt
    24361 gaagtggaat ttgtatataa tggaaatcga gatattgaaa ttgtagatat acaagagtta
    24421 gaatctggaa taacttttaa atatgatgaa atcttaagtg tacattcaaa agaacctaca
    24481 ctagaagaag tttttattaa atacacagga aggatgttag tgtaatgtac tctaaatttt
    24541 ttaccttagt aaaaaaagat ttttggatga tgatttatgg taaatttttt gtgctgacac
    24601 ttggctctct catactttat tcgtgttata ttaattttgg ttatgtaaag tttatggatg
    24661 aagatagtta tcacaataat gtatatctat ataatccaga gaatataagc atgagtgcat
    24721 ctccattaat taatcaagtt tcttctatag gtgaattaaa agcaaaactt gatgaagata
    24781 caagtgcagt ttgtattgat atgagttcca gtaagccgaa agtaatttta catgaaagta
    24841 ttaaaggagt tgacgattat agagctgact atgcattgtc attattatca tcagaaaaag
    24901 accacaatag caaaatatca gacaacaatg caataattca aattaatgat aaggatacat
    24961 ctgagataaa acaaagaaaa gacatgactt gtgagatttt attctttgaa attgtagcta
    25021 ttggattttt agggattgcc tctttattat ttaaagaaaa gcagatggga gtaatgcgta
    25081 ttactggtat tttacctgta aaaagaagtc tttttatatt atcaaagata tttgcttttt
    25141 tgatatgtga cctatgtttt acagttcttt tagtagtatt taatattgga ttttttgaag
    25201 gaataaaaat acttccacaa gtattagttc aagctagtat tttatcaatt attatgtctt
    25261 tgattggaat aggatgctca atgttattga gagattttaa gcaattttct cttatatatc
    25321 ttgtggttgc tgtattcata actacaccta tatttctatc tgcaaataca tcttttgaaa
    25381 tagattggat taaatatcat cccttctatc atgtttatag tcagcttaaa aatgcgtttt
    25441 tcatgaattt ttcaaaagaa ttagtttatt ttgtagtgtg ttctttgaca ataatagttc
    25501 tatttttact tgtaaaatat atttttaata aagagttggt tagggaggga taatcttgat
    25561 aggattacgt taccagttaa agagtataaa aaaagataaa atgtgtataa tttccttctt
    25621 tttaccagtt gttatggcga ttttaataaa ttttatggga acaattgata tatcttcatt
    25681 aggagagata cgttttggta tagtgaagga tacacttcct gtacaaacag agcagtggtt
    25741 gaagaagtat ggtatggtaa gtgtatatga cacaaaaatg catttaatac gtgaaattaa
    25801 ggatattaaa acagacacaa ttggagttgt tagagatggt aaagggataa aaactgtgct
    25861 ttatggaaat gagattaatg ctataaaaaa tgttggaaag acattgccag agatgtttag
    25921 actaaagggt gatttaaaag atgttgaggt tacaatattg cctaaagata gtattttaaa
    25981 agagtttcaa aatgttttta ttgccatgat tttaattact gctatgttta tgggatgcac
    26041 ctttaatgca atgaatatta tatctgaaaa agaagatgga atatcattta taaatgaagt
    26101 tttgccacag agtagaagtc agtatattat acaaaaagta tttttgggtc ttttatgtgg
    26161 gtgtttatct tcaatgataa ctgtatttat atgtttggat atttcaatat tagatatgat
    26221 aatgatgttg ttactcgttg tattttcagc atttatttca tcacttatag gtttatttat
    26281 tggaaagttg tcagaaggtc ttatggtagg aattgtttat attaaaatag taatgatttt
    26341 atttataggt actcctttgt taatatatct tctaggggtt aataccagtg gtatagggaa
    26401 tttatactat ataatgcctt cagttgctac atttaatggt attatggaga ttattaatgg
    26461 taatgtcatt attatcaaag atattgtaat tttggctgta cattgtgtag tatggtttat
    26521 gatatatatt attttagata aaaaaagaaa gttatttttt agtagataac tcagtataat
    26581 tataattggg acaatttaat aggtgattta atatactttg tatagtgtaa tttatgtagt
    26641 gcaatttgta tactttaatt tatgtagtgt aatagttagt tttattttat aattattcaa
    26701 tataatttag taagaagttc agtacaatta gagctactta gtggaaaact taataggtac
    26761 ttaaactata taaatacttt attttcctcc atttgtacta taaatttaat ttatgatata
    26821 aatggaggta ttattatatg atttgataaa tttcatcatt ataacctaca agtaaaggta
    26881 ttattatata aagttaataa agatagtatc aaaatattat ttgctataaa gagaggggct
    26941 caaaataaag ataaacctat ttttcaatgt tgaaatgata aaatatattt gatttcatat
    27001 aaaaaatttt cttcataaat taaaaagtcc attttaagcc ccctcatttt taaccagata
    27061 aatcgagtta aactatttaa atatattact cggattcatt tgacttagat attccttgct
    27121 tgtaaaattg ttttgaatag gggatagcca aagcaaaaaa taaaagtata atccctgcta
    27181 tgattattaa attattaata gaaattacat ctgccattgg tccgaaaatc atcataccaa
    27241 gaggaataaa accagtatat ataataatag gtaagctaag aactcgacct agcatttgtg
    27301 gtgctacatg ctcttgcaac atagtcatag ctgatgcttg aatgattgga attgaaaaat
    27361 tcgtaaaaaa cataaatata aaaaattgcc aagcttgtgt tacaagacct agaataattg
    27421 aaaaaatagc ataggataat attgctagaa aaaaggtctt atttctattt ttaaaaccac
    27481 caaaaactcc tataatcaat ccacctaaaa ccatacctaa aaatccaatc atttcaataa
    27541 tagacaggta tatataaccc ttgccaaatg ttcgttcaat aagaagtcct ataagaaatc
    27601 ctgatggaac acaaagaagc atgaatgctc cataagtaaa aagcactttt ctaatgaact
    27661 tatctgaaaa acagtacttt atccctgata ccatatctgc aaaaaatgag actttttcag
    27721 tttgttttgg tatatcatgt ttaggaattt tgatgaatat caataataca atagcaataa
    27781 ttgcagtaaa tacatcaatt aaaagaactt gatttatttt attaccaaat ccaagtattg
    27841 cagcagctac aataggaact ataaattgta ctatagattg taggctacta tttataccat
    27901 taaaacgcat taaatgttct tctggtacaa gttgaggaat cattgcgttt acagcaggtg
    27961 tttgtacacc acttcctagt gaacgtataa cagatattac tgatatggct attaattcac
    28021 ttgttgtgcc atttgatgac atcataaata gaattagaac taatgtagat atagcaattg
    28081 ttgaatctga tacaattatg agtacctttc gattgtagta gtctgcccat acaccagcaa
    28141 aaaaagaaat tatcatttga ggtataaagg agcatacagt taaaactgtt acccatacac
    28201 ctgatgatgt ctgaagtgtg acataccata tcattgccat ttgtacaagt gatgagccaa
    28261 ataaggaaat atattgactt gctaaaaaaa gaatgacttt tttcttccat gtagaattag
    28321 tatttttgtt ttccatccta ttcctccttt gatttgtgtg ttgaattttt cttgctctta
    28381 aggataacac acaaatcaaa gtctggagtt agagtggagg gctaggaaaa ttgttttttc
    28441 ataatttgaa gatgagattt catggttttt gcattatgtt cagcttcttt caatgaagtt
    28501 atcagtttgt cacacactga gataatttcg tcatcatctt ttggagtgtc aaggacagtt
    28561 ttaatattag tattaggatt agaagataaa gcatttaaca ttcgtaaaat agctgaaaga
    28621 gaatagtttg cacaacgaag tgcgcttata attttaagtc gttttatatc ttcatcagta
    28681 tatacacgat aaccattttg ttttcttttt acttttaaca aaccattcat ttcccaattt
    28741 cttaaagtat ctattgtaac gtttaagtgt tctgcagttt cttttctagt taaaaagagt
    28801 ttatttgttt ctggagtatt tccatttaaa atctgtgcaa caatagtaag tgcttcctcg
    28861 gcattagatt tttctatttc taattgttgc aagtattgat ttacaagact aatagcctta
    28921 tcaaagtccc tattcgctga tgttcttaca atctcaaggg catcttttct taatcccctt
    28981 tgtaccactt caattttcaa ggctgtacga gcaaatctaa attgttctat atgaaaatca
    29041 ttaaagatac gataaccatt ggtattacgc ttaggtttag gtattaagtt tagttcttca
    29101 tataaacgta ctgtattagg atgtacacca attaaatctg ctacctctga tgtcgtgtaa
    29161 gtgtccatta gtattcaact ccttttagat atatagtatt agtcataata acaccaaaca
    29221 aaagtctggt gttataatgg agggtttggt tatctaagag taattaattt atgaaagagt
    29281 aattaatcta ttatagaagt aagtatatat ttttcaataa actcccatct atcacgaggt
    29341 ttaaacacta ttttagatgg tatggctatt actaagtcat attgtggaat acaacaaata
    29401 gcatttcctc cagctcccat tgctgaatac cacaaaacac catctttttt acatagccac
    29461 cacagataac cgtattcatt actattcatt ttaactgatt cttcaatcca cgatttagat
    29521 ataatacgtt tattattcca aataccatca tttaaataca gaaaaccaaa tcgcaacata
    29581 tctctagcac tcaatgtaag tccccagcca cctatagaat aaccctgtct atcttttgcc
    29641 caacccttaa gattttttcc aaagaaatct tcaaaaccaa aatctttcat atcataatct
    29701 ggtataactt tcataccaat aggtttaaat aagtattcat tagcaaattc acgagcagat
    29761 tttccagtag tttttgttat aatagctgaa agtaggtgcg ttccagctga agaatatttg
    29821 aaagtaccaa tttcgccttt ttgaccaagt tgattcaagg tatattttat ccaatctttt
    29881 tgtttgcaaa gtctttctaa agactcagtc atatttttaa aagggtatgg tgcagtcatt
    29941 gtaagtaggt gacgtatagt tactgctttt ttacatattt cagaaggact ataagtatat
    30001 tcagggaaaa aatcaacaac cttttggtca acatctttta tatatccttt atctattgca
    30061 atacctatta aggctgatat aatacttttt gtaactgatg caacatgaaa agtatcatca
    30121 gcattatatc cattatagta cttttcaaag acaacttttc cttttcttgc aataattatt
    30181 ccatttatat tactatattg tgagattatt aaaggttcaa gttgtgagag tttttctgaa
    30241 ctcatgccaa cacttgaagg atttactttt tcaaatatta aatctaagca attgttttta
    30301 ttcattaaag atacctccct gttatagatt ttggattttc ttttagagtt tttggagaac
    30361 cttctgcaat tatataacct cctttgtcac caccttctgg accaagctca acaatccagt
    30421 cacaaacatt taatacatct atatcatgtt caacaacaat tacagaattt ccattttcaa
    30481 ccaattcatc taataattga atcaacttag aagtatcgta tagacttaga ccagtagttg
    30541 gctcatccaa tacataaagg atattaccat ttcgtttttt accaatttct tttgcaagtt
    30601 tgattctttg ggattcacca ccacttaaag ttggtgtagg ttggcctaat tttatatacc
    30661 ccatacctat ttgttctaat acatttaagt gtgaaacaat atttggaata tccttgaaga
    30721 aatgtacaga ttcagaaaca ctcatattta aaatatcatg tatattttta tttttatatt
    30781 taatagataa agattcatca ttaaatcttt ttccctgaca ttcactgcat atatggtcta
    30841 tacttagatt atttcccaac cagacctttt catatccact accactacat ttaggacaag
    30901 cccctttgga gttaaatgag aaatgaccag ctgtaaatcc tcgttctaac gattctggct
    30961 gacctgcaaa tagtgtacgt atcttatccc atataccaat ataagaagca ggagttgagt
    31021 tcatattttt gccaatagga gattgagata tctctgaata tccagaaata tgtttagtac
    31081 caatcagtct atctgcaata gtttcaacaa ctgcataatc gtcttcctca cctatttcac
    31141 tctctgaaga atttatttga ttattgatag tatggttatt aaattggctt ctaagaagag
    31201 gaagtagggt gtctgatata agtgaactct tgccactacc tgattttcca gatattccaa
    31261 ccatagcacc caaaggtaat gatacagtta catttttaag attatttgta tttgcatttt
    31321 gaatagttat acaaggtatt ttatcagtat gtgtaatgtt tttattgctt gttctattag
    31381 gcattggata ttttccagat agatactgtc cagtgagtga tttgtcggat tgaagtagac
    31441 cttctaaatc tccttgatat actaattgac caccttcaac accagctttt ggaccaatat
    31501 caataatatg ttctgccatt ttaattgtgt ttttatcatg ctcaactact atgaccgtat
    31561 tgcctaaatc tttaagtttc tttattgatt ttaagatgtc tattttttct gattcatgca
    31621 atccagctgt tggttcatca agcacataaa ttaatgagtc catctctgaa tcgagatgtg
    31681 aatttaaaaa tagtctttgc atttccccac cactcaaagt tgacatttct cggtataagg
    31741 atagatgacc taatcgtgat tctattaaat gttgagtttt ggataaaata tcatttacaa
    31801 gatttgtacc aaatgtgttt aaattacctt gatttattaa gagtttaagg aaatcatcaa
    31861 tttctaaaat cgtcattttt ccaagttctc caatatgttt tccgtttaaa agtactctac
    31921 gtgcttcttc accaatttta aaaccattgc aatctgaaca ggcagtcata gtataaactc
    31981 catttaaatc ttcgcccctt ttgtaacgat tgtgaaatac ctttgataaa gaggaacttt
    32041 ttttaccatt ttcataatga ccatagagta cttcatttct tacttcttca ggtagttgta
    32101 agaattgtat gtctaaataa tcattgaatt ttttagaaaa tactctcaaa tatccaggtg
    32161 taatctttgc tctatctaag acttgtttta gggtatcatg cttatcaagg actaattttt
    32221 caatattaat ctcaaaatat gcaccatgtc cagagcactt catacacatt ccatctgaag
    32281 agttgtatga gaaataactt ggtcttaatc gttcttcctc atatccacaa ttattgcaaa
    32341 ttagattata gcttacagga gtatcacaca tagtacacat tatttgacct tccactgaat
    32401 acaatagtgt aagcatgttg agaatattgg ttcttgtgcc tactgttgaa cgaggattgc
    32461 tctggcgaat aatattttgt tgaacagcta tagtgggagc taaaccttga atattatcaa
    32521 acttatcttc actatcaata cctgcaagta tacctaaaga ttgcagatat tgtttacgcc
    32581 cttcctcaaa tacaatgtca aacataaggc tagacttacc tgagccactg acacctgttg
    32641 caacaacaag cttatctttg gggatagaaa catctatatt tttaagattg tgtatctttg
    32701 ctccattaat ttttatttct ttcattggtt cacctcattt tatcaatttt atcaaaccgt
    32761 aaaataggga tatattaatc cttaatacaa gaatagatta ggtgaggtta ttaaaaaggt
    32821 tctataggta aatatatatc gaccaagtgt ctattttgag ggtgattgtg tgggttgtta
    32881 agatatactt caaaagggaa ggaggcacgt agcttataat taccatttga tagccattca
    32941 ttatacataa aatcccacgc atcactatat tcagattttg aaatatcaaa atgtcccaca
    33001 agatattttc cagaaggtat tatcatattg ccaagattgt cattctcttt gacaacaatg
    33061 ttatctggaa tggtcatgca aatactagtc cttaattgat gctcctgtgt aaattgtgga
    33121 ttatcatgat aaatggctaa tatttgtgtg ttttcaagtc caagtagatt ctgctcactt
    33181 gcatatgtga ataaccgttc taaaagtttt gggaaagtac tggttagatt accatatgaa
    33241 ccagtatacc tagtgtaaat agtattcata ttatcaagtt ctagaatttc aatttcacct
    33301 ttaacctctc tagtattctt acatttaggt tttgatatgc ttctattgta ctgagaaatt
    33361 ttatatggtt ctttgcaatt cttgctataa ttgtttctat attttatagg gcttatttta
    33421 tagtaatttt taaatgctct tgagaaaact gctgaatcag taaagccaaa gtagtgtgca
    33481 atatcagtaa cagtcatgtc agttctatga ataagaaaag cagttgcatt ttctagtttt
    33541 agcctattta catattgtgc caaagtttct ttttctattg ctttgaagat tctatgaaaa
    33601 tgaaattttg aaaaacctgc tatattagaa agttcatcaa gagaaagagg ttcatgtaaa
    33661 tgttcttcta tatagtcttg cactttgcaa atacgattta gatattcttt tttactttta
    33721 gcatttgtca tatatagccc tccttattgt gtaaaatgtg tatcaattaa tttatagcaa
    33781 tatagtaata aaattttatg tttttgtaat ttatgataaa taagatagcg tttaattttt
    33841 tataattgat aaaagatatt tataattaat aaaagatatt tataattaat aaaagatata
//
LOCUS       DAYAKB010000038        33267 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.038, whole genome shotgun sequence.
ACCESSION   DAYAKB010000038 DAYAKB010000000
VERSION     DAYAKB010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33267
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.038"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            358..1782
                     /locus_tag="ACGI3L_002158"
     CDS             358..1782
                     /locus_tag="ACGI3L_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFG9197867.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            1808..3946
                     /locus_tag="ACGI3L_002159"
     CDS             1808..3946
                     /locus_tag="ACGI3L_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9197868.1"
                     /translation="MDNLKKKKITSRQKKIILMIVANSKKNIPITISEIAGTLELSSR
                     TVLRDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEER
                     NLIILSKLLVSNEPVKSYYFAKILKVSEWVLNNDFALASKWLERFDIELVRKPGLGVY
                     LKGQEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCI
                     IRKVEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITE
                     EFKLAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITN
                     KMIDLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYD
                     VVEKISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSR
                     FLSTKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSL
                     DDEQIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEK
                     FESKDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERID
                     IMKLSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKI
                     NKFSIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            3976..4398
                     /locus_tag="ACGI3L_002160"
     CDS             3976..4398
                     /locus_tag="ACGI3L_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9197869.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            4417..5568
                     /locus_tag="ACGI3L_002161"
     CDS             4417..5568
                     /locus_tag="ACGI3L_002161"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9197870.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      5674..5775
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            5958..6530
                     /locus_tag="ACGI3L_002162"
     CDS             5958..6530
                     /locus_tag="ACGI3L_002162"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFG9197871.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            6594..7244
                     /gene="fsa"
                     /locus_tag="ACGI3L_002163"
     CDS             6594..7244
                     /gene="fsa"
                     /locus_tag="ACGI3L_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFG9197872.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            7396..10320
                     /locus_tag="ACGI3L_002164"
     CDS             7396..10320
                     /locus_tag="ACGI3L_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197873.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVMKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            10909..11367
                     /locus_tag="ACGI3L_002165"
     CDS             10909..11367
                     /locus_tag="ACGI3L_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9197874.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            11428..11703
                     /locus_tag="ACGI3L_002166"
     CDS             11428..11703
                     /locus_tag="ACGI3L_002166"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9197875.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            11762..13036
                     /locus_tag="ACGI3L_002167"
     CDS             11762..13036
                     /locus_tag="ACGI3L_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFG9197876.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            13166..14218
                     /locus_tag="ACGI3L_002168"
     CDS             13166..14218
                     /locus_tag="ACGI3L_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9197877.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            14218..15249
                     /locus_tag="ACGI3L_002169"
     CDS             14218..15249
                     /locus_tag="ACGI3L_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HFG9197878.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            15341..16153
                     /locus_tag="ACGI3L_002170"
     CDS             15341..16153
                     /locus_tag="ACGI3L_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFG9197879.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            16156..17076
                     /locus_tag="ACGI3L_002171"
     CDS             16156..17076
                     /locus_tag="ACGI3L_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HFG9197880.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            17251..17697
                     /gene="rpiB"
                     /locus_tag="ACGI3L_002172"
     CDS             17251..17697
                     /gene="rpiB"
                     /locus_tag="ACGI3L_002172"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HFG9197881.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            17727..18392
                     /locus_tag="ACGI3L_002173"
     CDS             17727..18392
                     /locus_tag="ACGI3L_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFG9197882.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            18502..20004
                     /locus_tag="ACGI3L_002174"
     CDS             18502..20004
                     /locus_tag="ACGI3L_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFG9197883.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(20316..21908)
                     /locus_tag="ACGI3L_002175"
     CDS             complement(20316..21908)
                     /locus_tag="ACGI3L_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HFG9197884.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INYYYKEFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLNMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(21877..22593)
                     /locus_tag="ACGI3L_002176"
     CDS             complement(21877..22593)
                     /locus_tag="ACGI3L_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197885.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(23133..23933)
                     /locus_tag="ACGI3L_002177"
     CDS             complement(23133..23933)
                     /locus_tag="ACGI3L_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFG9197886.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(24247..24978)
                     /locus_tag="ACGI3L_002178"
     CDS             complement(24247..24978)
                     /locus_tag="ACGI3L_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF364 domain-containing protein"
                     /protein_id="HFG9197887.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEICAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(24965..25660)
                     /locus_tag="ACGI3L_002179"
     CDS             complement(24965..25660)
                     /locus_tag="ACGI3L_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9197888.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(25662..26453)
                     /locus_tag="ACGI3L_002180"
     CDS             complement(25662..26453)
                     /locus_tag="ACGI3L_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197889.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAIILSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILYTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(26463..27275)
                     /gene="modA"
                     /locus_tag="ACGI3L_002181"
     CDS             complement(26463..27275)
                     /gene="modA"
                     /locus_tag="ACGI3L_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9197890.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(27909..28109)
                     /locus_tag="ACGI3L_002182"
     CDS             complement(27909..28109)
                     /locus_tag="ACGI3L_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011723062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9197891.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(28334..28510)
                     /locus_tag="ACGI3L_002183"
     CDS             complement(28334..28510)
                     /locus_tag="ACGI3L_002183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197892.1"
                     /translation="MFRDKMDKCTHMLTAYISNSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(28564..28653)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(28833..29033)
                     /locus_tag="ACGI3L_002184"
     CDS             complement(28833..29033)
                     /locus_tag="ACGI3L_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197893.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(29035..29385)
                     /locus_tag="ACGI3L_002185"
     CDS             complement(29035..29385)
                     /locus_tag="ACGI3L_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HFG9197894.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            29547..29735
                     /locus_tag="ACGI3L_002186"
     CDS             29547..29735
                     /locus_tag="ACGI3L_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197895.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGESELKIKKFSILYGSS"
     gene            complement(30212..30412)
                     /locus_tag="ACGI3L_002187"
                     /pseudo
     CDS             complement(30212..30412)
                     /locus_tag="ACGI3L_002187"
                     /inference="COORDINATES: protein motif:HMM:TIGR04223.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(30771..31259)
                     /locus_tag="ACGI3L_002188"
     CDS             complement(30771..31259)
                     /locus_tag="ACGI3L_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HFG9197896.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            32063..32437
                     /locus_tag="ACGI3L_002189"
     CDS             32063..32437
                     /locus_tag="ACGI3L_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9197897.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            32542..32916
                     /locus_tag="ACGI3L_002190"
                     /pseudo
     CDS             32542..32916
                     /locus_tag="ACGI3L_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT        13145 a         3779 c         5314 g        11029 t
ORIGIN      
        1 ttgtatagtt tacattgata atattactag agagtgcata aacctcaaaa atacagataa
       61 attaaatcta tattagtata tccaaaagta catttaataa atttatttaa ctgaattatt
      121 attttcattt ctattaaatt taaatatttt ataaaaatag tattatttac aaaatcatat
      181 actccaaaat actacataaa taaaattaaa caaaaactaa aatgacaaat gtcattatct
      241 aaagtgacat agaaacggtt tcttaaagtt gttactataa aatataaact ctataataaa
      301 agtataacaa aagggaatca tatcgatata gaatataatt caagaggagg taaaattatg
      361 agtagttcta atcaatcgac aataaagaca tctatacagc gagtagggaa atttttaagt
      421 ggtatggtaa tgccaaatat aggagctttt atagcatggg gtcttataac agcattattt
      481 ataccaacag gatggatgcc taatgaaaaa ttgagtacta taggtgaccc aatgataaaa
      541 taccttttac cactattgat agcttatact ggtggtaaag caatagcagg acaaagaggt
      601 ggcgtaatag gtgcagcagc agctatggga gtaattgttg gtgcagatat accaatgttt
      661 attggagcaa tgataatggg accatttgca ggatgggtaa ttaagaagtt tgataaattt
      721 gtagatggaa agataccaac aggatttgaa atgttagtaa ataacttttc aataggtata
      781 ataggtatgc ttcttgcaat actaggattt tatgcaattg gaccagcaat agtagcaggg
      841 acagctctta tagaatctgg agttcaattt atagttagca aaagtttatt gcctctagtt
      901 tcagtattta tagaacctgg aaaagtatta ttcttaaaca atgcaataaa tcatggtata
      961 ttagggccta taggtatagc tgaggcaaaa gaagcaggta aatctataat gttcttacta
     1021 gaaagtaacc ctggaccagg tttaggagtt ctattagcat attggatgtt tagtagagga
     1081 agtgtaaaac aatcagcacc aggagctgta ataatacatt tctttggtgg tatccatgaa
     1141 atttacttcc catatatttt aatgaatcca gttttaatat tggctacaat ggcaggtgga
     1201 gcagcaggaa tattgacttt ttcaatatta ggagctgggc ttgtagcagc accatcacca
     1261 ggaagtatat ttgcacttat ggcactagct ccaaagggag gattacttcc agtattagca
     1321 ggagttgcag tggcaacagt tgtatcattc ttagtggcag caccatttgt taagagagct
     1381 tcagcaaatc aaagtgaaga agacagtact tctttagaag aagctaaagc aaaaatgagt
     1441 gatatgaaat ctgcaagtaa gaactctgag aaaaatattg aggaaaaaca gcttgaagta
     1501 aatgagatta agaagattgt atttgcatgt gatgcaggaa tgggttcgag tgcaatggga
     1561 gcttccagat ttaaaaatag aataaaaaac ttagacttaa atatagaaat tacaaattca
     1621 tctgttgata atcttccaga tgatacacaa atagtagtaa ctcacaatac attagttgaa
     1681 agagttgcta agaataattc aagtgttgag atagtttcaa taaacaattt tttaaatgac
     1741 ccaaatttag atacattgtt taaaagatta gaatctaaat aaaaataaaa agtaccacta
     1801 attaggagtg gataatttga aaaaaaagaa gattacatct aggcaaaaaa agataatact
     1861 aatgatagta gcaaattcaa agaaaaacat tccaataact atttctgaga ttgcagggac
     1921 tttagagtta agttcaagaa ctgtacttag agatatgtct ggaattgaaa aatggtttga
     1981 tgaaaatgat tttaactttg taaaaaaacc aggagtggga ttgattttag aggaaaatat
     2041 agaaaatcaa aactttataa ttgagttgtt agaagaagaa aaaatagaaa aagaatacag
     2101 caaggaagaa agaaatttaa ttatattatc aaagctacta gtttctaacg agccagtaaa
     2161 atcctattat tttgcaaaaa tattaaaggt atctgaatgg gtactgaata atgattttgc
     2221 cttagcaagt aaatggttgg aaagatttga tattgagctt gttagaaaac cagggctcgg
     2281 tgtctactta aaaggtcaag aaaaaaactt tagagaggca tatgtaaatc ttatatacga
     2341 ttcattcaat gaaaaagaaa tactagatat ggtcagaaat ataagtgaaa atatacaaac
     2401 agataaagca atagaaattt taagtgaaaa tagactttta aatttaatgg acaggtgcat
     2461 aataagaaaa gttgaagcta cattaacaaa gaagctttca gatttagatg taaatttagc
     2521 tgatagtgca tatatagggc ttgtagttca tatttcatta gccttacaga ggataaaaaa
     2581 tggtgaaaat ataactatgg ataaagagtt tctaaaagaa ttatctataa cagaagagtt
     2641 taaattagct aaagaaatcg taaaaggtat ggaaacagat tttaacatgg atataccagt
     2701 agatgaggtt ggatatataa ctatgcatat aagaggtgca aagcaaaggt catcttcaaa
     2761 ccataaggct ttaaacttag atgatataga aataatggaa attacaaata agatgataga
     2821 tttggcggaa gatgaattta aaataagttt aaaaaatgac gagaggttat ttaaagacct
     2881 agcaaatcac ttagggcctt ctataaatag gttgaatatg ggattagaaa taagaaatcc
     2941 tcttttagat gaaataaaaa gcaagtattc atatgcctat gatgtagttg aaaagatttc
     3001 tagaattata aaagataaac taaatataaa ttcaatacct gaatcagaaa taggatatat
     3061 tgcaatgcac tttgcatcag ccatagaaaa aaatcttatg atgaatacta atataaatat
     3121 tgttgtggca tgtcccactg gaataggtac ttcaagattc ttatcaacta agattgaaaa
     3181 taaatttcct aatttaaata tacttgaaac catatcagct ataaacatag atgaagagta
     3241 tttaaaggaa aaagatgttg atttaatagt gtctacagtt gagttaaata caagtttaaa
     3301 ttatatatgt gtaggtccat ttatgagttt agatgatgaa cagataatca aggaaaaaat
     3361 aaaatctata gctcaaaata aattaatcaa tttaaatgcg aaaaatgata ctaagagtaa
     3421 gaataaagta tatgaacaga taacagaaag tatgaatata ggaaaagata ttcttcaatt
     3481 tttagaggaa attagatttg aaaaatttga aagtaaagat ttaagtgagc ttattgaaga
     3541 ctcatcaaaa atatttgcaa aatctagtga agatataatc tctataaaag aatcgttaaa
     3601 agaaagatta aaaatttcaa ttccatatat agaagaatca aaaattctat tgttacattg
     3661 tatgagtgaa agaatagata ttatgaagtt atcaataata aaactagaga atagaatcgt
     3721 gctagattca aatgaagaaa tcgacaatgt agtttttatg ttacttccta aaaattcacc
     3781 aagttatcaa agacaaataa tgagtgaaat aagtggttca ttaatagaca atataatttt
     3841 tactaataag ataaataaat tctctataga agagatggca ttagaggtaa aagatatagt
     3901 ttttaatttt tatacaaaca gattaaaagc atttatagat aaataaaatt aatattaaaa
     3961 aggaaggttg atactatgag taaagtattg aatgagaata atatattttt agggttagat
     4021 agtgtttcaa aggaagaagc tataacttta gcaggaagaa aattagttga aaatggatat
     4081 gtaaaagaag aatatatacc agcaatgtta gaaagagaaa aagtaatgac tacatatatg
     4141 ggaatgggag ttgctattcc acatggtgta aatgaagcaa aaaaagaaat attatcttct
     4201 ggaatagtta tattacaatt ccctaatggt atagattttg atggagaaaa agcatattta
     4261 ttaataggaa tagctggtgt tggagatgaa catttagaaa tactatctaa tatagcagta
     4321 gttttagatg atgacttaac agaaagacta aaaaattcaa atgacaaaca agcttttatg
     4381 gaagcttttg ccaactaatc ttaggaggga tttaaaatga aaaaggcaat tcagtttgga
     4441 gcaggaaata ttggaagagg ttttattgga ggcttgttag ttaagtcggg ttatcatgta
     4501 gtatttgctg atgtaaatga ggagatatta aactcaataa acaaagataa aaagtatact
     4561 atacacataa gagatgtaga atgtatagat gaagtaattg ataatataag tgcggtttca
     4621 tctataaaag aagaaataat agatgagatt gtacaggctg aaataataac tacagcagtt
     4681 ggacctttag ttttgactaa aatagcctct acaattgcaa aaggtataaa ggctagaaaa
     4741 gaaaagggat taacaagtaa tctaaatata atagcatgtg aaaatgcaat atacgcaagt
     4801 tcttctttaa aagaagaggt acttaagtat ttaaataagg aagaagtaga atatttagag
     4861 atgtatgttg gttttccaaa ctgttcagtt gatagaatag ttcctcctgg taaaaacgaa
     4921 aatcctcttg atgtaacagt tgaaaatttt tatgagtgga atgttgaaaa acaaggattt
     4981 aaaggggaaa taccaactat agttggtatg aatttagctg ataatcttat ggcttatata
     5041 gaacgtaaat tgtttacact gaatacaggt catgctataa cagcttatat aggatattta
     5101 aaaggatata agactataga agagagtata aaagataaat ttatctgtga tatagtcaaa
     5161 agtgcaatgg tagaaagtgg agaaggattg attaaaaaat acaattttga ctcagaagtg
     5221 cactataaat atattgataa aattttaaat agatttaaaa atccatatct taatgatgat
     5281 gtattaagag tcggaaggga accattaaga aaactaagtg ataaagatag attgattaaa
     5341 cctttaatga cagcaaaatc atatggatta tcagttgata atttgattct tggaataggt
     5401 gcagcgcttc attataataa tagtgaagat actcaaagtg tagaattaca agagttgata
     5461 aagtctattg gagtaaaaaa agccgttgct aaaatagcta atataagcaa tgacgaagaa
     5521 cttttaaaca atatcgaaaa aagttatata tttatgaaaa atttataaat ttacttgaaa
     5581 aaaagtagtt ctgataaagt aactataata tattattcta cacagtttga attatttgtt
     5641 gaataataga gaattataat atataattaa aaggaataaa ttaatatatt tacctgtata
     5701 tgtttgataa tatggttcaa atgtttctac taagctacca ttaatagctt gactacagga
     5761 gtgaagaaga tatagtttat acttatttta aattatatat taagttaatt actttgaatt
     5821 ttaagctcct gtctatgata tagacaggag cttttttagt attttaatat aaaatactta
     5881 caagaataga tagcaaaatt agaacaaata taattttttt attaatataa ttttagaaag
     5941 ggctaggtgg aagttcaatg aaggctttac aagaaaagat attgagagaa ggcagtgttt
     6001 caggaaatga tatactaaaa gttgatagtt ttttaaacca tcaaattgat gtagcttttt
     6061 taaatgaaat aggaagagaa tttaaagaga gatttaaagg agaaaaggtg gataagatat
     6121 ttacaataga ggcttcagga atagctatag catcaattgt ttcacagtat tttgataatg
     6181 cacctgtagt atttgcaaaa aaatcagaat ctaaaaattt ggataaagat gtatatgaaa
     6241 ctaatgtata ttcatttact aaggcaagag agtattcagt taaagtttct aaaaagtaca
     6301 taaacaaagg cgaaaatata ttgatagtgg atgatttttt ggcaaatgga agagctgctc
     6361 ttggacttaa agatttaatt gagcaagcag aagctaactt agttggagta ggaattgtca
     6421 ttgaaaaagg atttcaagct ggaggagcac ttttaaaggc taatgatgta agattagagt
     6481 ctttggcagt agttgaatct atagataatg gaactgtaaa atttaggtaa tttatgatat
     6541 tatatacttg tgtttagcac atattttaac tatgtaatta tggaggattt tttatgagat
     6601 tttttataga cacagccaat attgaagaaa taaaagaagc aaatgattta ggtgtaatct
     6661 gtggtgtaac tactaatccg tctctaatag ctaaagaagg tagagatttt atagaggtag
     6721 ttaaagaaat aagtgaaata gtagatggac caataagtgc agaagtaata agtttagaac
     6781 ataaaggtat gatagaggaa gcagaaaaat tatctaagat acataaaaat atagttataa
     6841 agatacctat gacagcagaa ggtctaaaag cggtgaaagt actatcaagt aaaggtataa
     6901 agactaatgt aacgcttata ttctctgctg gacaagctct tttagctgct agagctggag
     6961 ctacatatgt aagtcctttt gttggtagat tggatgatat atcacaaaat ggtcttgatt
     7021 taattgaaga aatcgttgat atatttagtg taaatagtat tgaggctcaa ataatagttg
     7081 ctagtgttag aaatccaata catgttttac aagctgctag aatgggagca gatatagcaa
     7141 cagttcctct taaagttata aaccaaatga ttaagcatcc tttgacagac aaaggaatag
     7201 atagctttat gaaggattgg gaaggtgctt ctttaaaatt ataattataa actacgcttt
     7261 ataagtatat taaagaggtt attatggaaa ttctaagtaa taaggctagg ctattttgcc
     7321 tagtcttatt ttggtgtata atatattgaa acatattatt gaaatagatt aattttttaa
     7381 gtgaggaggc gaaaaatgga taaaatatta agagagatac aaagagaaga taaaaaaaat
     7441 ccatatactg accaagaact tgctgaaatg ttaaatgtag ctaggtctga agtgatatca
     7501 gttaggaaaa aaaataatat tttagattcg agagaaagaa gaaaaaaaat attaataaaa
     7561 gatatatcaa aaattgtaag tgaaaatcct caaatgtctg aaagaaaaat aactgaaata
     7621 ttaatagaaa atggatataa tatatcgaga agtgcagttt caaaattatt aaaagaggaa
     7681 aatttaaatc agtcaaagat tgggattaag gataaagacc cagcatcatc aggaaagtat
     7741 gtgaaggtga gtaaagttgt agaagaagat ggatttgaag aattgatagg tataaaggga
     7801 agtttgaaag aaaaggtaaa tctagctaag tcagcaataa tgtatcctcc taatggcctt
     7861 catactataa tatatggaga aacaggagta ggtaaaagtg aattagctac atgtatgtat
     7921 aaatatgcta taaaaaacaa cattaaagaa gagaacagcc catttatagt gtttaactgt
     7981 gcagactatg cagaaaatcc taatctattg atagctcaac tctttggggt agtaaaaggt
     8041 gcatatacag gagcagatgc aaatagagaa ggtcttgtag aacaagctaa taatggaata
     8101 ttgtttttag atgaaattca tagattgcct gctgctgggc aagaaatctt attttcatta
     8161 atagatagag gagaatttag aaggttagga gaaagtagtt ctaatagaaa ggcaaatgtt
     8221 ctcataataa gtgctacaac agaaaatcca gattctaatt tacttcaaac atttagaaga
     8281 cgtataccaa tggtaataaa tttacctaat atgagtgaaa gaccaaaatc tgaaagatat
     8341 gaaataataa taaagttttt tgaaagagaa gcaaagcgag taaacaagaa ttttataata
     8401 actaaagaag ttatgtgtgc acttatgaat tataagtgta ctggaaatat aggtcagtta
     8461 aagagtgata tacaagtaac ttgtgctaga gcttttagta aatcgatatt ttctagcgat
     8521 aaagtaatta tagatttaga tagtttaagg gattatataa aaagtggata ttatgattgt
     8581 aattgtaaaa atgaaaagta ttctgagttt tcagttgagg atatatatat agatattagt
     8641 gaattggtga gtggaaaaaa tagaatttta tctgataatg agataagcga gatatataat
     8701 tatgcagaaa aagagcttaa ggttttggaa agtaagtgct tttcagaaga agagttaaaa
     8761 aatgcattta tagaaaagtt agataagaag tttaatgcta ttaaaaacaa taaaaattta
     8821 tctgatagaa gaagtcgaat agactgggga ggacaattaa aagagtctac actggagata
     8881 atggataagg taattgtatt tattaaggag cagtttaagc atgtaaatca aggtctgtac
     8941 ttggctctag caattcatat tgagcatgct ataggtagga taaaagatgg aaaaactata
     9001 ataaatccga gtttagataa aataaaagca tcaatgccaa tggaatatga gttgtcaaga
     9061 tatataatgg gtatagtaga agatttgaca caagtaacat ttccagaaga tgagcttgga
     9121 tatttggctt attatataaa taaattttgt tataatgagg aaagtataaa agataaagtt
     9181 aaagtagtaa tagttacgca tggtaaagtt ggaattgaaa tgtctaaagt tgtaaatcat
     9241 attttaggta tagaatgtac actaggtata gaaatagcac ttacagattc accatcagag
     9301 gggatagagc atgtattaga agaacttcaa aagatagaag ctagaaaagg tattctagtt
     9361 ctaattgata tgggttcttt ggtaattctt ggtgatgagg ttgaaaaaag gcttggaatt
     9421 agatgtaaaa ctgtaaatag agtagataca ttattggcaa tggaagcagg aaaacttgca
     9481 acaattgaag gaaaaagttt agatggtata atagctgatt taaagaaaaa taagaattat
     9541 gctatgataa atacaaataa atttagttac agaaaaaacg agtatggaaa gaaaaatgta
     9601 atcattactt tatgtttgag tggtgtaggt acagctttaa atttaaaaga gcatatagaa
     9661 aaacaaatta aggaatatga cactttaatt gaagtaaagc cagttgcttt tttaaataat
     9721 aatttagaag aagagttaaa tgatattgaa tctgaatata atattattgc tatctgtgga
     9781 actattgata tagattataa aaacgtgcct tttatttctt ataatgaggt acttggtaaa
     9841 aatggtatta ataaagtatt agagcattta aatagtaaac aaccagcttt aaatattgaa
     9901 aaccagttga ataatttaat acatgaagat ttgattttat acaattttga aggaatttca
     9961 aaggagtata taattgatac tcttgtttca aaacttgaag aaggtggata tgttgactca
    10021 aagtatatat taagtgtata taaaagagaa gcaatgggaa gtgttgtaat ggcctctaag
    10081 gtagccgtgc cacatggact tccagaaaac gttatgaagc ctgcaatagc aatcgcgagg
    10141 ttgaataaac ctatagtatg ggacaataaa tttatggtgg atttggtggt actactggca
    10201 cttaaagaaa ataataagaa agaaatacga agcttatttt caaagattaa tgaccagcat
    10261 actttagaag ttttattaaa tactgaagat aaaaatgaaa taaaagaact tttaagctaa
    10321 ttattagtac cgagaagaaa gacaaaaaaa tttgctttag tataaaattt aaaactactc
    10381 aattgctaag tagttaatta ctctatataa ggctagttct atgaaattta tttatatgat
    10441 tttatagaat tagctttttt cttggtaaat aaaatatata aatttattta tgtaaaaagt
    10501 aaattttatt ggacaattct ataaaaattt ttcctatatt tcttataaaa tatagaatat
    10561 ataaaaaata tataaaaata aattaaattc ataataaata attttataaa atagttgtta
    10621 aacataaaaa accatttgta aaaaacaaaa aaatcatttc tctaacaaaa aaaaccacaa
    10681 aaaatataaa aaagtatggc tagttaagtg attaacaagt aaaaattaaa ataaaaatca
    10741 aaaaaaattt atcaatgaaa gtcagctaaa atcctggaag agagcattat ttttgggaaa
    10801 acattttctt ttgtttcaca aaaaaagcca ctttttggca cacaacatgc tttatataaa
    10861 gtcaagaaaa actaaggtat aagacaaagg caattaggag gtgtaaatat ggagtttata
    10921 aattttgtaa gtgataaagt tatagacctt aaaatggatt gtaaaacgaa agaagatttc
    10981 tttaaagaaa tacataataa agtttttgat ttaggctttg taaaagaaga atttggagaa
    11041 aaaatattag caagagaaaa tgtatttcca acaggtttaa atttaggtga ttatggagta
    11101 gcaataccac atacagatgc ggaatatatt aaagagcaat ttatatcagt ctgtactttt
    11161 aatgaaccag tagtatttag ttctatggaa gaccaagatg aaaaagtacc tgtaaatttg
    11221 gctttcgtat taggacttaa tcaaccacac agtcaattat ctgtattaac agaattaatg
    11281 ggaattatgc aaaataaaga gttagttgat aagttgatga gttctactga taaagaagaa
    11341 gttttaaaga cactaaagtc tttataaaaa taaaaaagta ctaaaaataa aaaatataaa
    11401 aataaaaatt attaggagga aataaaaatg aaaaaaatat tagtagcatg tggagcagga
    11461 atagcaacat caacagtagt ttgtgacaag gtagagagat tagttaagga aaataatata
    11521 caagcagaag ttatacaatg caaaatagct gaatgtgcaa caaagcaaga aggagcagat
    11581 ttaatagtat caacaactat actaccaaca acttataata taccagcaat aaaagcaaca
    11641 gcatatataa ctggagtaaa tacagcagca ttagataaaa aaatattaga tgctttaaaa
    11701 taatcctatc atagatacat tgaaataata ttttataaaa cagaaaaagg aggatttata
    11761 aatggataaa ttattagcag tagtacaata cattttaaat atgggaccga cagtaatact
    11821 accaataaca attgtagtac taggaatgat atttagaatt aagtttacaa aagctttaaa
    11881 gtcaggtctt acaattggta taggatttgt gggtataaac ttagttgtaa acctattaac
    11941 atcaacacta gggccagcgg ctcaaggaat ggttgaaaga ttcggactta atttaacagt
    12001 aatagatgtt ggttggccaa caacagcatc agcaacatgg gcttcaccag ttgcaccaat
    12061 attaatacca gtttgtttat tagtaaactt actattatta tacttcaata aaacaaagat
    12121 attaaacgtt gatatatgga attattggca ctttatagta gcaggtgcag ttggatatat
    12181 agtaacagga agttatgttt gggctatatt ctgtgcaata ctaatggagt tattagtact
    12241 gtttattgca gaaaagacag caaaaaatgt tcaggagttt tatgatttag aaggtatagc
    12301 attaccaact ggttcaacag cttcatttgc tccacttgga tatttagtag gtaaatttgt
    12361 tgaaaaaata ccaggaataa ataaaataca agcagaccca gactctatac aaaaaagatt
    12421 tggtatattt ggagaaccaa tgatgatggg gattatacta ggtataatac ttggagcact
    12481 tgcgggatat gatgtagcag gaatattcaa tgtaggtata tcaatgggtg cagtaatgtt
    12541 acttatgcct agaatggtta gaatattaat ggaaggttta attccaattt cagaatcaat
    12601 aagagatttc ttacaagcaa aatatggaga cagagaactt tatataggtc tggatgcagc
    12661 agtagcaact ggacatccag cagttatatc aacagctctt atacttgttc ctataacttt
    12721 gttcttagca gttatactac caggaaacaa agttttacca tttggagact tagcgacaat
    12781 accattttat atggcattta tagtgtgttt tagaaaaggt aatatagttc aatcagttat
    12841 aacaggaaca atagtaatag ctatatcact ttatatggct acaaactttg cagatgttca
    12901 tacacaatta ttacaacaag caaatatgat gccagaagga acaacaatgg ttacaagtat
    12961 agatacaggt ggaaacttgc taaaatgggg aatattgaaa ttatctcaat tagtttcttc
    13021 atttggaata ttctagtatg tagttaatag agattactct tttttagtaa agtatgcgaa
    13081 aatttaacat ttagcagcta ctaaaaaaga gtaatatttt ttataaattt ttaaaaatac
    13141 aaaatacaag aggaggagat ttatcgtgaa agcagcagta ttacatggca caaatgatat
    13201 gagatttgaa gatatagaaa taaaaccatg tgaaagtgat gaagtaaaaa taaaagttat
    13261 ggcagcagga atatgtgggt cagatcctcc aagagtatta aaacattgga aatatccagt
    13321 tccagctata ccaggacatg agttttctgg agtaattgct gaagttggta aggatgtaaa
    13381 aaatgtaaaa gttggagata gagtagttgc aattcctttt ataccttgta atgaatgtga
    13441 atattgtaaa agaggattat tttcattgtg tgatgaccat ggaatgttag gagctaaaag
    13501 ttttggagct tttgcagagt atgtaaatat aaaagctaca aatgtacttc caataggaga
    13561 tatgaacttt gaagatgctg caatgataga gccactagca gttgctatgc atggagtact
    13621 taatataggt gttcaagttg gagacactgt agctgtaatg ggtagtggaa caatggggca
    13681 gttggtaata caaggactta aaatagcagg ggcaggaaca attatagcag ttgatatatc
    13741 tgataataaa ttaagagaat caaaggaatt aggggctgat ataataatta atgctaaaga
    13801 tattaaccca gtagaaaaaa taaaagaact tactggtgga aaaggtgttg acatagctct
    13861 tgaatgtgca ggttcaaaaa taactcaaga acaatgttta cttataacta aaaagaaaag
    13921 taagatagga tttttaggga tagcatattc agatataact ttatcagaag aagcatttga
    13981 aaatatattt agaaaagaac tagaattaaa aggtttttgg aactcttatt ctgcaccatt
    14041 tccaggacaa gaatggacta agggaatcaa tctagttaat gaaggaaaga taaaattaaa
    14101 agaaatggta tctcatagat tctcacttga agatacttac aaagcatttg aaatgataag
    14161 agatagaaaa gaagaattta acaaaatatt aattttacca caaggggttg aaaaataatg
    14221 aaagcagtag ttaaaactaa accaggctat gataatgtag aagttttaga agtagaagaa
    14281 ccaaaagcta caggagacaa ggttaaaata aaagtagaat atagtggtat atgtggttca
    14341 gatatacatt catttaaagg tgaatatgca aatataaaag ccccagtaac attaggtcat
    14401 gaattttctg gaattgttgt agaagtagga gaagatgtta aaaatataaa agtaggagat
    14461 agagttacat cagagactac ttttgcaact tgtgagaaat gtatatattg tgaaactaaa
    14521 gattataact tatgcccaac tagaaaaggt attggtactc aagtaaatgg aagttttgct
    14581 gagtatgtat tatcaagaga agaaagcata catgtacttc ctgaaaatgt atctttatta
    14641 tcagcagccc ttacagagcc actagcttgt tgtgttcatg cagctcttga aaagactact
    14701 atagaaagtt ctgatacagt tttaataata ggaccaggac caattggttt attattagct
    14761 caagttgtta aatctcaagg tgctacagtt ataatgtctg gtgttacaaa agataaggaa
    14821 agattagaaa tagctaaaaa tcttggagta gatagaactg taaatgtaat ggaagaaagt
    14881 ttggcagatg tagtgaatga aatgactgat ggaaatggag taaacaaagg atttgattgt
    14941 tctgggttta tgccagcagt taacgaagcc ttaagactgc ttagaaaaaa aggtactttc
    15001 gtacaagttg gaatctttgc taaaaaatta aatgaaatgg accaagaagc aataatccaa
    15061 agagagttac aatatatagg aagcaggtct caaaagccaa gttcttggat tacagcatta
    15121 gatttaatgg caaatgggaa agtaaataca gaagctttag ttactagaac tgttggttta
    15181 gacgaattta aagaaggtat tacagcttta atgaacgggg aagaaataaa agtagcagta
    15241 aaatcttaaa aaaacatttg tattatttta aaaaaaattg taaaatctac tgtaggataa
    15301 aaaaatgtaa ggtcttaaaa aataacagga ggaagaaagt atgagcactc ttagagatca
    15361 ttctaataat attagaaaaa acataataaa aatggttgca gaagctaaaa gcggacatcc
    15421 aggtggttca ttatcaatag ctgatatgtt gacagtatta tattttgata agatgaacgt
    15481 atgtgcagaa aatccaaaaa tggctgatag agatagattt gttctatcaa aaggtcatgc
    15541 agcaccagct ttatatgcta cattagcaga aaaaggattt ttcccagaag aagaattaat
    15601 aacactaaga aaatttggtt ctaagttaca aggtcaccca gacatgaaaa aagtagcagg
    15661 aatcgatatg tctactggtt ctcttggtca agggctatct gcagcaaatg gtatggcact
    15721 tgcaggaaaa ttagataaca aagactatac agtatatact atattaggtg atggagaaat
    15781 ccaagaaggt caaatatggg aagctgcaat gacagcatca cattacaaat tagataattt
    15841 aattgcattt gttgacttaa atggattaca aatagatggt tctaatgaag aagtaatgaa
    15901 tgtaagtcca gtagatgaca aattcaaatc ttttggatgg aatgtaatag taataaatgg
    15961 acattctttt gaagaaatag gaaatgcagt tgatgaagct aaaaaagtta caggaaaacc
    16021 aactgtaata atagctaaaa cagtaaaagg taaaggtgtt tcatttatgg aaaataatgc
    16081 tgcatggcat ggaacagctc caaatgcaga acaagcagag caagcattga aagatttaga
    16141 aggaggtcta taggaatggg aatagcaact agagaagctt acggacaagt gttaaaagaa
    16201 cttgcagaaa ataaagatat agtagtatta gatgcagatt taggaaaagc tacaaaaagt
    16261 atatcattta aagaagttgc cccagataga ttttttgaca tggggatagc agaaggtgac
    16321 atgattggta cagcagcagg tcttgctact tgtggaaaaa taccttttgc gagtactttt
    16381 gcaatatttg cagcaggaag aggctatgag caaataagaa actctgtagc atatccaaat
    16441 ttaaatgtaa aaatagcagc tactcatgca ggtgtaacag taggtgaaga tggtggtagc
    16501 catcaagcta tagaggatat atctctaatg agaggtatac caaatatggt tgtattaaat
    16561 ccagcagatg ctttagaagc aagacaagct attcttacat ctattgatta taatggacct
    16621 gtttatataa gattaggtag agctgcaact cctgatgtaa acagtgaaaa ttataaattt
    16681 gaaataggaa aaggaactgt tttaagagaa ggttctgaca taacagtaat agctacagga
    16741 ataatggtag caaaagcctt agaagcagca gaagaacttg ctaaagaagg tataaatgta
    16801 gaagttgtta atatatctac aataaaacca ttagatgaag cattaataaa agaaactgct
    16861 aagaaaactg gaaaagtagt tacagcagag gagcacagta taataggtgg tttaggttca
    16921 gctgtatgtg aagctttagc agaaactaaa gatgtagtag ttagaagaat tggtgttaaa
    16981 gatgtatttg gtcaatcagg tacaccagct gatttattaa aacactatgg tttaactaca
    17041 gaagatatag taaaaaatat aaaagagttg ttatagatat aaatatatct aaataacaaa
    17101 ttgatttgac ataagtcaat taaagctgtc ttaaaaatag aaagaaattt ctacaatggg
    17161 acagctttat ttttacaata ctttattttt atgataatta taaaatagtc tgaaagtaat
    17221 caaaaaaatt ataaaaagag gtgctattta atgaaaatat ctattggatg tgaccatggt
    17281 ggttatgaat taaaggaata tataaaggaa aatttaataa ataaaggtat agaagttgaa
    17341 gatgtgggta caaattcaaa agaaagtgta gattttccaa tatatgcaaa aaaggtaagt
    17401 caaaatgttc aaagtaaaaa atctgattta ggcatacttt gttgtggaac aggaataggt
    17461 atgtctattg cagcaaataa gtttaaagga atcagagcag ctgttgtttc tgactgtttt
    17521 tcagctaagg caactagaga acacaataat acaaatgtac tttgtttagg agaaagagtt
    17581 attgggaaag gattagcaat gagaattgtt gaagaatggt taaattcaag ttataatgga
    17641 gaaagacatg caagaagatt acaaatgatt gatgatatag aaaaagaaaa tttataaata
    17701 tataatttat aacaaggggg agcgttatgt ctattatttg tgcttcaata atgtgtgcag
    17761 accaaatgaa gttaaaagag gaattagaag ctcttgaaga agcaggtgta aaattacttc
    17821 attgtgatgt tatggatgga atatttgtta aaaacttggc tatgggacca gagttattaa
    17881 aatcaataag tgaaaataca acaatacctt tagacataca cttagccaca gaaactccag
    17941 ataaatatat tgatatgatg tcttatataa agccaaaata tatttctttt catgtagaat
    18001 caagtacaaa tgtaaaagct gatatacaaa agttaagaaa ttatggtata gggccagtgt
    18061 tagcaataag ccctcaaaca agtgtggata aaatagaaga atatataagt ttagttgagg
    18121 gtatcttagt aatgacagta aatccagggt ttgcaggtca aaagtttaat ctttctgtat
    18181 tggataagtt ggataaactt acagagatac taaaagatta tgataatcct ccatttatag
    18241 aggttgatgg aaatataaat aaggatacta ttaaacttat gaatggtaaa aaagtagata
    18301 tatatgttgt tggtacttca gctttattta atgataagcc tccaatttca tataaagata
    18361 aaatagaaga actaaaagaa agtataaagt aaccatgtaa taaaattata atatgtttct
    18421 gtttaatagt aaaaatttag gtggaaacaa gaaattttat aatatttaat aaaaattttg
    18481 gttgagtaag gagaattttt tatgggagac ctatataaac tacaaaatgg tactgatatt
    18541 agaggaatag cgtatgaaaa tgattctaaa gaagttaacc taactgtaga agaagtaaaa
    18601 aaaatagcta aagcgtttca tatttggtta aaagaaaaga ctaagaaaga taaagtaact
    18661 gttgccatag gaactgattc taggataaca ggaagccaat ttagaagtac tgttattgaa
    18721 actttaacta atgacgattg taatgtaatt gattgtgaga ttgccacaac tccagctatg
    18781 tttatgacaa ctattatgga tggatacaat tctgatgggg cgattatgat tacagcaagt
    18841 cacttacctt attactataa tggtttaaag tttttcacag aaagtggagg tttagaaaaa
    18901 actgatataa aagagatgtt ggatatagct gttaaaaatg atagtgtaga ctatgaggaa
    18961 gtaaataaaa aaggtgaagt tatagtaaaa aatttaatag aagattattc taatttattg
    19021 atagataaaa ttagaaaagg tgtaaattca agtaaaaatt atgaaaagcc tttttctggg
    19081 cttaagatat tggttgatgc aggaaatggg gctggtggat tctttgctga aaaagtttta
    19141 cacatactgg gagcagatac gacaggtagt cagtttttga acccagatgg tatgttccca
    19201 aatcatatac ctaatcccga aaacaaagaa gcaatggaaa gcatatgtaa agctgtgtta
    19261 gataataaga gcgacctagg aataatcttt gatacagatg tagacagagc tgctattgta
    19321 ggtaaaaatg gcaaaccaat aaataaaaat gctcttatag ctgttatatc atcaatagta
    19381 ttagaagaac atccaaaaac agctatagta acagattcga ttacttctga aggacttgct
    19441 aaatttataa atgaattaca aggaagacat catagattta aaagaggata taaaaatgta
    19501 ataaatgaag ctataagatt gaatagtgaa ggtgaagagt gccatttagc tatagaaacg
    19561 tctggacatg ctgctttaaa agaaaattat ttcttagatg atggggcata tttaatagct
    19621 aaaattttaa taaaagtagc aaagctatcc ttggaaggaa agactataga agaattgata
    19681 gaaaaccttg aagaagctca agaagagaaa gaagttagaa taggcattaa taaagaagat
    19741 tttagaccat atgcagagga tatattaaaa gatttagatt ctcatgtcaa gagtattgat
    19801 ggatggtctg tagcaccaaa taattttgaa ggcataagag ttaattgtga tgaatcaaat
    19861 ggagatggat ggtttttact tagaatatca ctacatgaac cattattagc tttaaatatt
    19921 gaatcaaata aaattggcgg agcagaacaa atttattcta agttaaaact tttcttagaa
    19981 aaatatgatt taaaaggtct ttagggtaaa tagaaagaat atatttatat tgaagaataa
    20041 atgtaaattt gtacctaaga ttacaaatat tacaaaattg taatcttagg taacagagat
    20101 gtaactgatt atggaaacac tatgtgatat tatagataca gagagatgaa atatgtgatg
    20161 aattatagag aaatataatt taaaatgtat taatatcaca ccaaaaaggt ataatcaaaa
    20221 aatatgtaaa tataaacccc aacatttaga agaagacctc taaggaggtt tttttcttgt
    20281 ttaaataact taaaatatat ttttatatca atatatcaat taactcttct aaaagtaagc
    20341 attaccttaa ataaatcagc atctataatt atttccatgt gtgcattttc taattcaatt
    20401 atattttgag caattgataa accaagacca gagccatctg tttttctaga tatatcaccc
    20461 cttctaaatc tttctattaa ctcttctggc tttagattta gtttatcatt tgaaatattt
    20521 ttaaacgtta atattatatt ttcttccttt ataaacatat ctatgtagac cctagtgtta
    20581 ggcatagagt attttagtat attgcaaatt agattctcaa aaactctcca agttttttta
    20641 ccatctatca tggtaaaaac agcatattca ggtgtttcta ttataaaatc taaactgcta
    20701 ttttgaattt tgtcttcaaa ctctacaata ctttgaatta aaagttctct tatatcggtt
    20761 tttgttatat taaattctac atctccacta cttagcttag atgcttcaaa tatgtcatct
    20821 attaataatt ttaatctttg tgatttttta tctaaaatat ttatatagtc atttatagtc
    20881 tctctgtcaa agtcattatt ttttaacata tcaacatagc ttaatataga tgtaagtgga
    20941 gtttttaagt catgagatac gtttgtgata agctctgcct tcatcctttc attttttata
    21001 ttagcatcta cagcagtttc aagaccacct gttatattat ttatactttt ggctaaagta
    21061 gatatttcat catctcctat aacttctaat ttatacttta aattgccatt ttctatattt
    21121 tttatatttt ttgatatgtt atttatgtaa ttaaacttaa cagataaaaa gttgtatata
    21181 taaaaatgaa aaactgtgtt tacaagtgta aataaaatta ctatagctat tgcctcagca
    21241 taatatatat acataaagaa tatcaaaaca agatattgga taatagcttg tacaactata
    21301 gatattaaaa atactatagc taatttttta tttatagttt ttttattata catattaagc
    21361 aagtttgaaa aaaatacata tgttatagac atatctttta gattatagtt attatattta
    21421 atattttcat atattatata gactatagat ataattataa aattgtagat tattaaatta
    21481 gtgttgtaaa acattttatt acttgtaaat gcatgaaacc ttaaggttaa tagtatcaaa
    21541 gttaatataa gtgtaagttc tatttttacc ttagaaaaaa ggcttatgac attctctaag
    21601 aatttgactt tagtctgttt atttttttta tacaatgtaa aacatagtat agtcaataaa
    21661 aaacttgata atataatacc tatgcagaca aactctaatt ctacttttga caaatgtaca
    21721 ggagtaccga aaaaataaaa ataagggaga gcaaactctt tataataata attaatatta
    21781 taagaaaagt tattattcaa atcataaact gcttcaaata atatagaaac taatagaaac
    21841 agtaataata ataaaataaa ttttgcttta gaatcattaa taattaagtt tttcaatttt
    21901 gtaaccaatg ccccacacca cctttaaata ttttggttct tttggattaa tttcaatctt
    21961 ttctctaatt cttctaatat gaacagcaat agttctctca caactataag catcctcatt
    22021 ccagacattt tcataaatct catgagaaga gaaaatttta ccttttcgtg acataagaag
    22081 tgtaagtatt ttatattcaa gtggtgtcat tttaatttct tcaccatcta aagaaactat
    22141 ttttgtatct gtatttagct ctaggccacc actttttaga atataattag tatcatttga
    22201 gttatttgta ttactaaaat cacctaaatt tatatacctt ctaagttgag attttactcg
    22261 agcagtaagt tctagtggat taaatggttt agttatatag tcatcagcac ccatattaag
    22321 acctataatt ttgtccatat cttctgattt tgcagataag agaattattg gtatattcct
    22381 tttttctctt attttaagtg tagttttaag cccatctaaa ttgggcatca ttacatccat
    22441 tattattaac ttaatatcat tttcgattag tatgtccaat gcttcaagtc catcatatgc
    22501 ctttaaaaca ttaaagttat caggtctcaa atagaactct atagcatcaa ctatctctct
    22561 atcatcatct acaaccaata tattttgatt caacttatta acccccttga aattttattt
    22621 ttaaccaatt tttattttat accaaaaaga ggtattagaa aacagtaagc ccgttcatta
    22681 tgaaataaaa actagtactt ttaatatatt gtcaatgcat atagtaaatt taaaagtata
    22741 gacgcccata ttaatctgaa ggtaaaagtt tatgaaaata tctagggtaa tctatcacac
    22801 tccttatgtt attttggttt attaattttt taggtttaaa catatattaa caaatataaa
    22861 taacaaatga gtttcataat tattaagaat ttataacaaa tatttatttt aatgtagttt
    22921 aatataaata ggtagcttaa tgtagatatg tataaagcat ttaataaggc ttataggttt
    22981 taatgatgat atctttatat attttaagag atgatgaaat tagatatggg taatagttgt
    23041 atgagaaaaa gtagtatagc acaaaaagtg ctatatcaca aaatctcaaa taatttcctt
    23101 tttataactt aaattaaaag aataaatatt tcttataaat taggtgtatg aagtatagca
    23161 ggaacatctt tattatttaa taacttatca aatgatttat ggtcagactt atagccaata
    23221 ccttctctat attctaattc atcaacaatt ttgtattgtt gacaggcatt tttaaccttt
    23281 tcatagtctt cagtagaatg agctttataa actatcttat tattaaaagt tattttatca
    23341 gcaaatttag gttttacaaa atatttagca tcttttattt taccagcatt atataaattt
    23401 tggataacag aaccattttt taaatgttgt aaatggtcat ctaacttata agtatgtgct
    23461 atatgagtta catttttaaa tttttcttca aatgtaagag caattttttc catgtaattg
    23521 aagtcagtat taccatttgt atttgtttct ggtaataata ttatattttc ccttattaca
    23581 ccaaggctat taagagaagc taaaaattct ctatttctat attctgattt ttgtatattt
    23641 gttaggtttt catatttttt atatttatca aagacggata taccacatcc agtagatact
    23701 aaaaccacaa atacatgatt ttttcctctt tcttttatag cattaacaat agcactccca
    23761 gcccacaaca cttcatcatc ttgatgctga acatagaaga caacataatc tttaaatttt
    23821 ttatgactat aattcacata gctactaaaa gcggttaaaa tcaaacataa aactagaata
    23881 atagatagaa ttttatattt atttatagta aattttttat tcttaaatgt catttaatca
    23941 tctcctgaaa agttgtctta gttatattat caaacaaagt actaaaaatt atttcttaaa
    24001 tgctgaaaaa tatagagtag attaatggaa taaaattttt ttattagttt aaaataaaga
    24061 aaacatttat gtataagact aatcaaaata ttaatgattg ataggaattg agatttaaag
    24121 ggattgtaca tttattcggg attcatttta atagaatttt actttagtac ttagaataaa
    24181 agtaataact ttttaaattt aaagagtaca catatatatt tgtgtactcc ttgatgatat
    24241 gattgcttat ttactacaaa aacagagtct ttttaaacct aaaatatttg atgcaccagc
    24301 tatcgtagtt ccataatagt aaactggttt gttaagtgat agaaaattta taattgagtt
    24361 attacataat gtacttcctg tgcaaatcac taaatcagcc caagatatta catcttcata
    24421 atctcgtata ccatcttcaa tcttaacatt atattggata gtatccacaa attcaggatt
    24481 taaatctaat actcttgttt cgaaaaagtc cttaatatta tcaattatgg ctggttgata
    24541 tcctataatt gctacttttg gattaccaaa ttccattttt ataaactcag ggaatttttt
    24601 tgcacatatc tctggctcgt tatttttaca atgaatggtt ctatccgtct tgcctaagta
    24661 tttcataact gcatttaatg atgctataaa aagacttcta tcatgaggat tgtcatgtaa
    24721 atctaatgat aatatgtctt ttaaagaacc ttcaaatgta gatggagtag aagtaaatgc
    24781 ttgtccttta gctcctttaa agtcagcttc aagcattatt tctttaccaa ctataattgg
    24841 gaaatcttta cgcttagtat ttccaattgc ttcttttgaa gatagagatt tggacacaat
    24901 acttatcata tccatattta aattatattt atcaacttgt actaatagat aatctctcaa
    24961 aatatcaaat atattcatag aaaaaagatt ctcctttatt ttttatttct tcatttaaat
    25021 caaaaatatg atttattttt ccattgttca ttattcctat cttatgagca aaaaacattg
    25081 cttcagaaat atcatgagta acatgaatca ctgttggttt gtattttatg tagacatcct
    25141 tcaaaatttt gcttatatgt ttttttgtaa tataatccaa tgaactcata ggttcatcta
    25201 aaagtaatat atcaggttca gctattaagg cacgtgcaaa agcaactcgt tgcttttcac
    25261 ctccacttaa atttttagga tacctatttt ttatatcttc tatctgcatt aatttagata
    25321 agtggttagc cttaagaatc tgttcatcta taggtatttt tctcaattta agtggaaacc
    25381 ttatattatc ttcaacattc atatttggaa ataattcaaa attttgatat acaaatccta
    25441 tatttctatt ttctggaggt aagtttgata ttaaattttc tttgtatgat acatttcctt
    25501 tagcagatgg atatcttcct gctaatgttt ctagaaatag agttttacct gacccactag
    25561 ctcctaataa aacaaagtat tcatgattat taatatttaa actattttct tgtaatttaa
    25621 aattaggtaa atcaagagat aaatttttta tttttaacat attaattctt atcaacctct
    25681 ctattaaaaa atatctcaaa aagcatcaag catgtaagtg agataaatat caaaattaca
    25741 gctattccga ttgcaatgtc tatatcacca gtagacatat ttaaatatat agatgtagga
    25801 ataatttcag ttttcatacg tgtagaacct gctatcatag ctactgcacc aaattcacca
    25861 agtgctcttg accaagtcat tacagttgca gatatgattc cagtttttag atttggaaga
    25921 attataaatc taaatgcttc ccaactatta catccaaggg tacgtgcaac aaatatcatc
    25981 ttttcattac tttcatttag tgaagtgtaa agtattttaa tagtaagtgg aagatttaca
    26041 aatacttgtg ctaaaactat accttgcttt gtaaatataa aatcaagctt aaaaatctta
    26101 taaatggaat ctccaatccc cattcttcca aacaaaagta aaagagcaat tcctgatact
    26161 aagtgtggaa gagacatagg gagatttatt atctgtataa tcagtttttt aaatggtaat
    26221 ttagtaatat gtaaaaaata tgctactgga atagctaata aaaggcatac tatagtagat
    26281 attaaagatg ttttaatact aagtattatt gcatactgta cttccactga ttttaagcat
    26341 ataggaacat aacttatccc tttaatgatt aacataagaa gtggtgatac aataaacaaa
    26401 aagactatag caaaaaatcc agtaagtaga gtagtaaaaa atttattttt caagtttaat
    26461 cactacttaa caggttcaaa accatatttt ttaaatatct gtttagcttc gtctgactct
    26521 atataattta taaatttatt agctaaatct tttttatcac tatagtttac gattcctgct
    26581 gatataagtt ggtctatatt tttatcttgg gcaatttcta taacttctac atcttcattg
    26641 ccaaagaccg aatcttttgt ggctattgta gcatcagctt tacttgatgt taactgtaca
    26701 atcatttcat ttacagttgc agctgtagag acaacattat catttataga ttttaaatta
    26761 tttttttcaa gtattttttg tgtagtctta cctatagcat tagactcttt gtctcccaaa
    26821 ataagtttaa ctccatcttt atttaagtct tccaattttt gaatattagc tggatttcct
    26881 ttaggtacaa ctattgcagg tgtatgatgt gcaaccgttt tatgttcacc tacaagttct
    26941 ttttcaaagg cttttgaata aattggttca gaaccaacaa taaatacgtc ccctttgtga
    27001 cttgtctcaa tttgagctat tagctgtgca gaacctgcat agctatattc aactttgaca
    27061 ttattttctt tctcaaattt ttttgctatt tcatccattg gtttctttaa acctgcccct
    27121 gaatagacaa aaagagtctc tttttctttt gaatcatcag ctgttgtcac tttagtatta
    27181 gattcatcat tagctttgtt ttctttagaa ttacatgcag taatacttaa tgaaataatc
    27241 atagctaaag ctagtactga aagtttttta aacataagat attccccctt agtaaattaa
    27301 tgtaaattct tttttagtat atcatactaa gaaaacgatg tctaagtttt tgttatgttt
    27361 tataatgttt tgttatgttt tgttatgtat agttaagaaa aaatctattt ataatgttat
    27421 ttctataggt agttatttta tttttaattt ttattaatac tttaaagtat tttaaattta
    27481 aaaacttaaa tcaaattaac ttattgtaga ttttttactt tttaactaat tttatattta
    27541 ttatatttca gtgaaaaaat agaacattga aacatataga tatgttttaa ttgcttttta
    27601 ttaacaaatt actaaaaatg ttatatcaga attgaataca aaagaaagag tatgtattta
    27661 tgagatagtt gaaaattttg atgtgccaca actaaaatta ttatattact atatatttaa
    27721 ttaaaagagt acttgtaggt ttaagtacat actttataaa tatatttttg ttagatttat
    27781 tttataaaaa gtatttagac taagtattat ttttaagtat tttcttgttg aagttatttt
    27841 ttcctttttt acaaaattcg taaataaaaa aaagactctt aaaagagtct ttccgaaaaa
    27901 tctatatatt ataatatagt tatattttct gcttgaggac ctctagcgcc tttaactata
    27961 tcaaagctta ctttttgacc ttcttctaat gatttaaatc ctgaagtttg tatagctgag
    28021 aaatgagcaa atacgtcatc tccactttcc attgatataa atccaaatcc tttttcatta
    28081 ttaaaccatt ttactattcc attattcatt aaaaatactc ctattaacct atatcaagat
    28141 atacttgatt tacttgtgta ttaccacaaa tattattgta tcatagatta acataaatgt
    28201 ctatttaatt ataattttta gttaacattt ttatttattc ttaatatgaa aataaattta
    28261 aacattttat attaccaata tattaatgta aatgtagata aaactaaaaa gggttttcta
    28321 gaaaaaaatc tgtctaatta tacttactta ccaataccat cacttgatgc aagcaagatt
    28381 ccacaacttt ttctccgtac tctaatataa aatcatctaa ctgtgtatct ataaaatcac
    28441 aataatcgta tgaattacta atataagcag ttaacatatg tgtacattta tccattttat
    28501 ctctaaacat aatgtattta tccccctaaa aaactttcat gaaaaacaaa aagaaaatat
    28561 ctttttggca actggctgac ataacttatt ttataagcgt tagtccctat agctttgcgt
    28621 cactaaattt ctctagtttt gccgatttag ttttattcta cagattaata atacaataga
    28681 attagttatc attcaacata tctagttgaa taattaataa atttatatat gaactttaaa
    28741 ttatttgaaa aaataaaaag cccctctgtc aggagtgact taaaaattga atttaagttt
    28801 gtatttaaaa cacattttta ataatgcaaa aactaatcaa aaataaacaa ttcatcaata
    28861 ggtgtatcta ctatttttga tatatctatt gctaatttca aagaaggatt atactttcct
    28921 gcttctaaac gcataatggt ttctcttcta actcctactt tttctgctaa ttgttcttga
    28981 gttaattctt ttaattgtct atattttttt aggttacaag tgaatttagg catattattt
    29041 ttcctctaaa atataaagtt ttatagcata aacatttaaa gtgattgcat atgtaattga
    29101 tagtaaaaca cacattaatt ctatattcct agacactata gtaatacacc ataaaatgaa
    29161 taattctata atagcaagct gtcctgtaaa tgccatagct gctttttcat cttgtacata
    29221 cctttcatct gctttatcac catttatttt tgctataata aagtttgaga aaaaagcaaa
    29281 aaatccaata tatgtaaggt cagcaacatt gccagatgaa aaatatctaa gacttaaaaa
    29341 tccaaggaaa ccacaaaaac ccataaaaaa ttttttctga atcatttttt atcctcctta
    29401 gtaattttaa aagagatata tttatatctt tatgatacaa atatatctct tttatattct
    29461 tttgtcaata gaaaatcagt attatacaat atttatactg caccataatt gttagagcaa
    29521 aaatctaatg cttgagatgt ttatgtatga ctaaatatga ttttaatttc aaattaaaag
    29581 tagctaaatt ttatttgaat agagaaggaa gagatatttt aatagtaaaa caatatggag
    29641 tttatgacca ttctcaagtt gaaagatggg ttaatatatt aggagagagt gaactaaaaa
    29701 taaaaaaatt ttctatacta tatggttcaa gttagatgtt ataaactata tgatgataac
    29761 taaatatagt gtacaataaa tcgctaagta ttttggaata aacaatagca cagttatagc
    29821 aacatgaaaa taaaaatttt tacatagtgg tgttgatgcc ttttctaaaa tgaaaggaag
    29881 accataatga ataaaaacaa aaacactaaa gaaaaaataa attaacaaga gaacaagaat
    29941 tagaatatga aaataaattt ttaaaagatg agcttgagtt tttaaaaaag atgtgtgtct
    30001 cagggaagcc acattaaaaa acagtggtat cattattaat caaaagaaag ttagatgtat
    30061 tatcaaaaaa ttagaactta aatgcatagc attttttcat aaatcacata aatataactc
    30121 ctataaaggt ataattggaa aagtaaaaaa taataaaaca aatagaagat ttaaaacatc
    30181 aatagcatat cagaaaataa caaatgatat gctagaattt ataaaatata tctaatgata
    30241 aaaatggaaa atcaattata aaaaaggcat atctcgattc attttttgtt atatagtcaa
    30301 ataagaatac tatagatgaa agatacgatt ttgcatatgt attaagtaag tattctgatg
    30361 tttttggttg atacacatgc aataaagaag ttgtgtttgc agataaatta gcaaaactat
    30421 agtataagtt gcaacaataa agaaaatgaa aattatcata ctaaagcata aggcatgtta
    30481 caattttatt agataggaca ttaacataca ctaaagtact ttttattata aagagtactt
    30541 atttttttga aattcattaa tgtataaact atcaagaata ttactcaaca taatttaaaa
    30601 acaacttgaa taggtatttt taaattatgt gatataataa aaaatagaag tgtatgccaa
    30661 tacacttctg tagttataac taagcattct attcttgagg agtgcttttt tcatttttat
    30721 aaccaactct ttttacttta acaataatta tcagacctat atatttattt ttaattgtct
    30781 gatttattag ataaaaaagt tattatcata tttttatcat ttggtatttt tattgaacta
    30841 ccataatctt cttctaattt atctagacca cttttactta tttctccatc tataattatg
    30901 tttaattcta agtattcttc actaccatta gatgacacta aagtgtacga accattataa
    30961 ggcatgccta aattttctat tttatgtgcc aaagggtctt catcaccaat accagagttt
    31021 actgttattt ttccatcttt tttagtccac catattatgt ttccttcagt atattttgat
    31081 tcatctgcat agtagctaag agacgcactt tttattgcac ttatatcagc ttcaagttta
    31141 gctatctttg ctttttctat atttttaaat aatgctggaa gtgctactat tgccaatatt
    31201 cctattatag caattactac taataattcc actagagtaa atcctttttt atttttcatt
    31261 tatttcccct ccatataaaa ttaataatat ataaattttt attttgttaa tttctacttt
    31321 ctatatttta ccatatatag acaaaaaaat cactttctat gacaaatata ctattatttt
    31381 acaatttatg gaaatgattt aaaatgacat ttcttgttag aaaagatata agaaatggat
    31441 taaaataaag aaaactacag tcatatcaat gtcaataata ttatttaaaa gcagatgaaa
    31501 ataaaaagag gactcagaaa ataatgtcta tttaattata cttacttacc aataccataa
    31561 cttgatataa acaagattat actacatttt tttatgctct agtataaaat catctaactg
    31621 tgtatctata aaatcaaaat aattatatga actatcagta taataagtca aaatatgtat
    31681 acatgaatac atattttaaa agatatatat tattacatac ctaaaaaact ttcataaaaa
    31741 caaaaataaa atatgctttt agtaacttgt taacataact tataatttat tttataagca
    31801 ttagcctata tagctttgtg ctactaaatc tctttgattc taacgattta gtgctattct
    31861 acaactaaaa taatacaata gagctattta ttgtttggta gcattgtttg taaattaaac
    31921 aaatttatac atatgaatat tattttacat tcaaaaaaac agactaaata tgtagaatat
    31981 ttggtaaaac ttacctctag tttttgtctt aaaaagctcc tattattaac ttaagttaga
    32041 agaattaagg aagtgacata aattgaaaga agaaatatta atagaaaaat tattaagagc
    32101 agaattaata gtaatggagt atttatggaa aaaagacact ctaatgccta aaaaagaaat
    32161 tgtaaaagaa ataaaacaga tttatggatg gcataaaagt acaataaaaa tactactaaa
    32221 aaggctagtt gctaaaaggt atttggctag atatattata aattctcaat ctcattataa
    32281 aataatagat agtaaagaat attatacttt taagaaaaag gtactaaaat ctagtaaaag
    32341 cataaaaata atgcgttcac ttaccactac acataaaaat gtaagtaaag agaagttaga
    32401 cctattagat gagtattata gaaacttaaa agaatgatat agtaaaaatc gaatgtaatt
    32461 atttacctta attcttttgt ttgtaaaact ttattgatac agaatttaac atatacataa
    32521 attggtaaag gaatgtatac tatgaaaatt agtaaattac cagaagcgga attaaaagtt
    32581 atgagatata tttgggaatc agaaaaggta ttaatatcaa gagaaatcac caagtctatg
    32641 gaacaaaaat atgaatggaa agatacaact atatttacag tattaaaaag attactaaag
    32701 aagagagttt ttagaagcgg agaaaataga taagtgtaca cactataatg tattagtaaa
    32761 aaaaaataat atcagagatt ttaaacaaaa gaatttttaa agaatacaca taaaaattca
    32821 atattaagtt taatgtcagc actatgtagt aaggatgatg aagtagatgg tgatatttta
    32881 aatttattag aagaatattt taagaatttg aaataagaaa atgacaaatt gatacataat
    32941 aaataaaatg aaggtatgaa attataactt tttctacctt cattttgttt attattctga
    33001 acatgttaag aaaatgaaat aagtttgtat tttatttata taaattttaa tagaatatgt
    33061 atagtatata gtagatagaa tgtataaaaa taaaaactgt tcaataagaa ttaatataca
    33121 ttaattcagc tgaatccaat caaaatactt aaataaaagt aatctgaaaa taacataatt
    33181 caaatcaatt tattcaaata aacctcaatt tatctcaaat cttaagaagt cattaaacaa
    33241 acttgctaaa ttacaaagag aattatc
//
LOCUS       DAYAKB010000039        33106 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.039, whole genome shotgun sequence.
ACCESSION   DAYAKB010000039 DAYAKB010000000
VERSION     DAYAKB010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33106
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.039"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            119..313
                     /locus_tag="ACGI3L_002191"
     CDS             119..313
                     /locus_tag="ACGI3L_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HFG9197898.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    482..715
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            792..2189
                     /gene="asnS"
                     /locus_tag="ACGI3L_002192"
     CDS             792..2189
                     /gene="asnS"
                     /locus_tag="ACGI3L_002192"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFG9197899.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(2362..3537)
                     /locus_tag="ACGI3L_002193"
     CDS             complement(2362..3537)
                     /locus_tag="ACGI3L_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9197900.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            3956..5320
                     /locus_tag="ACGI3L_002194"
     CDS             3956..5320
                     /locus_tag="ACGI3L_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9197901.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            5342..5833
                     /locus_tag="ACGI3L_002195"
     CDS             5342..5833
                     /locus_tag="ACGI3L_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9197902.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            6106..6777
                     /locus_tag="ACGI3L_002196"
     CDS             6106..6777
                     /locus_tag="ACGI3L_002196"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFG9197903.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            6847..7728
                     /locus_tag="ACGI3L_002197"
     CDS             6847..7728
                     /locus_tag="ACGI3L_002197"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008747 - N-acetylneuraminate lyase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HFG9197904.1"
                     /translation="MRTTDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGL
                     YVGGSTGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGY
                     DAISAVTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENE
                     KIIGVKFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRA
                     RQIFELTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKE
                     ATDEMKSRAKEIYRKYF"
     gene            7761..9263
                     /locus_tag="ACGI3L_002198"
     CDS             7761..9263
                     /locus_tag="ACGI3L_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HFG9197905.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            9393..9845
                     /locus_tag="ACGI3L_002199"
     CDS             9393..9845
                     /locus_tag="ACGI3L_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HFG9197906.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            10005..10808
                     /locus_tag="ACGI3L_002200"
     CDS             10005..10808
                     /locus_tag="ACGI3L_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HFG9197907.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            10866..11753
                     /locus_tag="ACGI3L_002201"
     CDS             10866..11753
                     /locus_tag="ACGI3L_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9197908.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGKDATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            11772..12620
                     /locus_tag="ACGI3L_002202"
     CDS             11772..12620
                     /locus_tag="ACGI3L_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9197909.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            12683..13372
                     /locus_tag="ACGI3L_002203"
     CDS             12683..13372
                     /locus_tag="ACGI3L_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9197910.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            13763..14770
                     /gene="asrA"
                     /locus_tag="ACGI3L_002204"
     CDS             13763..14770
                     /gene="asrA"
                     /locus_tag="ACGI3L_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HFG9197911.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            14771..15562
                     /gene="asrB"
                     /locus_tag="ACGI3L_002205"
     CDS             14771..15562
                     /gene="asrB"
                     /locus_tag="ACGI3L_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HFG9197912.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            15575..16546
                     /gene="asrC"
                     /locus_tag="ACGI3L_002206"
     CDS             15575..16546
                     /gene="asrC"
                     /locus_tag="ACGI3L_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HFG9197913.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            16603..17379
                     /locus_tag="ACGI3L_002207"
     CDS             16603..17379
                     /locus_tag="ACGI3L_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFG9197914.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLIDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     NTVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            17650..19668
                     /locus_tag="ACGI3L_002208"
     CDS             17650..19668
                     /locus_tag="ACGI3L_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFG9197915.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIINTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            19883..20740
                     /locus_tag="ACGI3L_002209"
     CDS             19883..20740
                     /locus_tag="ACGI3L_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9197916.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            20837..21706
                     /locus_tag="ACGI3L_002210"
     CDS             20837..21706
                     /locus_tag="ACGI3L_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9197917.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(22076..22708)
                     /locus_tag="ACGI3L_002211"
     CDS             complement(22076..22708)
                     /locus_tag="ACGI3L_002211"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HFG9197918.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(22801..23133)
                     /locus_tag="ACGI3L_002212"
                     /pseudo
     CDS             complement(22801..23133)
                     /locus_tag="ACGI3L_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
     gene            complement(23211..23414)
                     /locus_tag="ACGI3L_002213"
     CDS             complement(23211..23414)
                     /locus_tag="ACGI3L_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFG9197919.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            complement(23804..24034)
                     /locus_tag="ACGI3L_002214"
     CDS             complement(23804..24034)
                     /locus_tag="ACGI3L_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9197920.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(24036..24443)
                     /locus_tag="ACGI3L_002215"
     CDS             complement(24036..24443)
                     /locus_tag="ACGI3L_002215"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9197921.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            complement(24803..25252)
                     /locus_tag="ACGI3L_002216"
                     /pseudo
     CDS             complement(24803..25252)
                     /locus_tag="ACGI3L_002216"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(25266..26192)
                     /locus_tag="ACGI3L_002217"
     CDS             complement(25266..26192)
                     /locus_tag="ACGI3L_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197922.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            complement(26317..27099)
                     /locus_tag="ACGI3L_002218"
     CDS             complement(26317..27099)
                     /locus_tag="ACGI3L_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HFG9197923.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(27255..27875)
                     /locus_tag="ACGI3L_002219"
     CDS             complement(27255..27875)
                     /locus_tag="ACGI3L_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9197924.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(28002..28670)
                     /locus_tag="ACGI3L_002220"
                     /pseudo
     CDS             complement(28002..28670)
                     /locus_tag="ACGI3L_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            28741..29577
                     /locus_tag="ACGI3L_002221"
                     /pseudo
     CDS             28741..29577
                     /locus_tag="ACGI3L_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            30249..31016
                     /gene="aroD"
                     /locus_tag="ACGI3L_002222"
     CDS             30249..31016
                     /gene="aroD"
                     /locus_tag="ACGI3L_002222"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFG9197925.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(31344..32021)
                     /locus_tag="ACGI3L_002223"
     CDS             complement(31344..32021)
                     /locus_tag="ACGI3L_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197926.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(32171..32488)
                     /locus_tag="ACGI3L_002224"
     CDS             complement(32171..32488)
                     /locus_tag="ACGI3L_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197927.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(32510..32848)
                     /locus_tag="ACGI3L_002225"
     CDS             complement(32510..32848)
                     /locus_tag="ACGI3L_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9197928.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT        12535 a         3877 c         5415 g        11279 t
ORIGIN      
        1 ataaattaag tattgaaaag atattatgtt aatttaaaaa taattataat ttagacttat
       61 gaattttatt tgtaaaattg ctaaaactat tacaaaataa ataatagagg tgatagtttt
      121 ggaaagtaaa aaggcaagag cattaaaagg taaagataat aaaagactta aaagttcact
      181 tttagttgga aatgagtcga cagcagcatg ggctgatgtt gaaaaattaa aacctcatag
      241 taaagtttca ataccttcaa ttaagggtgt cgaagaagca aaagactggg ttgacaatgg
      301 aagtaaatta taaaattttg gaaattgaag taataaagaa gtaatgaaga taagtattta
      361 ttatcattat gtaaggtaga attattatat tttaaataac aatcagtatc aattatataa
      421 atttattgac taaaaattta taaattggta taattttgtt aattagcaga aataataaaa
      481 gataaatact gtgaagagaa gagtagatat aaaatgtagt tctagcgagt tgaggatggt
      541 gaaagctcaa tacgaggttt atattgaaga acatcttgga gtttctaatc gaaagcttat
      601 ttagtaagta gacttagacg gaaggcaccg ttataggctt taagcattgc ttaactaaga
      661 ggtcattatg acaactaggg tggtaccgcg agagtaatag tctttcgtcc ctttatatag
      721 ggatgaaggg ctttttttat tgaaattata tttaaaagaa attaataaca attatactag
      781 gaggatttaa aatgcaaaag gaatttataa cagtaaaaga attgtacaga gaaaaagaac
      841 agtacatagg gaagactgta aaagtagctg gatggataag aacatctaga gtatctaaaa
      901 attttggatt tatagagcta aatgatggaa gcttctttaa aaatatgcag atagtatttg
      961 atgagaaagt agaaaatttt aaagaggtag gaaaattagc aataagctca tctatacttg
     1021 tagagggaga gttagtatct acagaagggg ctaaacaacc agtcgaaata catgcaaaaa
     1081 gcatagttgt agaaggggaa tcagatagtt cgtatccact acaaaagaag agacatacgc
     1141 ttgaatattt aagaacgata gcacatttaa gaccaagaag taatactttt tcagctgtat
     1201 ttagagtaag atcaatagct gcctatgcaa tacacaaatt cttccaagaa agaaactttg
     1261 tatatgcaca ttctccaatc ataacaggta gtgactgtga aggtgcagga gagatgttta
     1321 gaataacaac tatggattta aatgatattc caaaaactga agatggcaaa atagactata
     1381 ctcaagattt ctttggaaaa gaggctaatt taacagttag tggtcaatta aatgccgaga
     1441 taatggcact ttcttttaga aacgtttata cttttggacc tacatttaga gctgaaaact
     1501 cttatacagg aagacatgct tcagaatttt ggatgataga gccagaaata gtttttgcag
     1561 accttgaaga taacatggaa cttgcagaag atatgataaa atatgttata agctatgtat
     1621 tagaaaatgc tcctgaagaa atggaatttt ttaatagttt tatagataaa ggattgttag
     1681 aaagattaaa taagatagta aactctgagt ttattagaat aacgtatact aaagcagtgg
     1741 aattattaat tgaatctggg catgaatttg agtatcctgt tgagtgggga tgtgaccttc
     1801 aaacagagca tgaaagatat ataacggagc aaatatataa ttgtccagtg tttgttacag
     1861 attatccaaa agatataaaa gctttctata tgagaatgaa tgaagatggt aaaactgtta
     1921 gagcaatgga tttactagtt cctggagttg gagaaatcgt aggaggttct caaagagaag
     1981 aaagagaaga tgtattgtta gatagaatta atgaaatggg attaagagaa gaagattatt
     2041 ggtggtattt agaacttaga aagtttggta ctgctactca ctctggattt ggtcttggat
     2101 ttgaaagaat aattatgtat atgacaggta tgtctaacat aagagacgtt atacctttcc
     2161 caagaactcc taaaaatgct gaattttaat aattatatat aataaaactt atataacttt
     2221 aagtataaac actaaaatga cttgcatatt tatctatttt agagatatgc aagttatttt
     2281 tattgtacta taaatatata atttgattac ttttattttg cgatataata cttataggtt
     2341 tatgtaatag tatgtaacct tttaataaaa tgcaacacaa ttacgtcctt gttcttttgc
     2401 agtatatagg gccttatcac aattacttat aaactcattt aatgttattg tctttccaat
     2461 tttctttgta taaactccaa tactaacagt tacacatttt aaaggaacat catcacgctc
     2521 aaaattgcag gactctataa tttttcgtaa acattctgat ttaagtttag catctgcctc
     2581 attacagtta aaaatacata taaaaaattc ctcaccacca tatcgtatag catgttcatt
     2641 ttcagaactt gtaaaatcta aaattacttt ggcaatattt tgtagacaat agtctccctt
     2701 ttgatgtcca taattatcat taaattgttt aaaataatct atatctatca tcattccagt
     2761 tataggttct tgatttgcat ggctgattaa ttttttttgt agaatatctt caaggtacct
     2821 acggttgttc attttagtaa ggtcatctgt cataactttg tcgttaagta aattatttat
     2881 atgagatatt tcttcatatt gttgactaat taaaagttta tcatagtaag taaatacacg
     2941 atttctatat agcattgtag aaacaaaaat ggcaagggat gttataaaaa atgtgttgac
     3001 aatattacta aactcattgc ctggtatagt ttgaatccca ggtaagaata aattaagaaa
     3061 caaaaagcat cctccaaaaa ctattactga ttctccaaat tttaatactg agaaagctgc
     3121 agctgctaac ataatataac taaatacact taggtcattt ccacctaact ggtcaagtag
     3181 agtaattaca caaccccata ggcagaaaaa agtcacataa attatccata aatttatata
     3241 aaacgtacag caatcctttt ttttattcca aaggtaagaa aatacaaaca taaagacaga
     3301 agatacacaa aatagtgtta catacatata aaaataccat tggcgtcttg gtgtgacaaa
     3361 agggcctcct tctctagctg agattgatat catcataatt atttgagata ttactattat
     3421 tatgcaaatg attttacccg tatgataaag ataattgcag agttctttct caacattgtc
     3481 tttgtgtttt ttgtctagag gaaatccaaa aaattttttt attttttcta agttcatata
     3541 agcctccatt aaaaataaag cataaaaata agtattcctt tctatcatta gatatttgga
     3601 atacttcgtt tatgatttaa ttatatcaaa atatattgtg tgtaacaatc taaaattgtg
     3661 atagataaaa tttattagat aatgtcgagt aactttattg attaatactt tattataatt
     3721 aagatttaca gatagtttac tactgaaaat aaagaataga ataaatttaa attaagcata
     3781 ataaaatata aataataaag ttcgcattaa caaactattt aaatatcaag acctgttaaa
     3841 aaacaacagt aataaacaaa taaaatagat aaatatatcc aattaaggta taattaagtt
     3901 ttatatgata tagttatatt tgataattta caatagtaaa acttggaggg aaaaaatggg
     3961 tgaaaagaaa ataaataata tgaattattc acataataat tattccaaaa agacaggtga
     4021 accaactaga aaaataaaaa atagccatat cactcttaaa agtaaagaag aaaaaatttg
     4081 ttctagttgc aataaagaaa ataatactaa ggataattac tgtaaatttt gtggaaatga
     4141 actttatgaa atagcatcat taagaccact tgaaacaaaa ctagacttga aatctaaaat
     4201 aaaagagctt tcatatcatg caaataaaag aggtgtattt ttaacaacat ttacaaccat
     4261 atttatattg tttattattg cattgatatt taaagctatt ataactattc aatttaatga
     4321 tattagttat ttaataaatc cagcacatat aatcctagct ctcaacttgg gtcaaattag
     4381 tgtatctatg tctaccatga tgggttctgg gtttataaat gccaatatag gtttgttgat
     4441 attacttata atccctattt tggtattatt aatatcaaac ctaattttta tgagaaaaag
     4501 atgtagagat tcaaaaactg tattagcaaa ttctctagga gttggaattt tttatggatt
     4561 agttttagct attttatcta tttttactaa tgtaaaaact agttcacata gtatgttaga
     4621 atatggatat gcattagaat atagttatga attttttagt gttcttttaa atggatttgt
     4681 attagggttt atatgtacat acataactac ttataaaaaa agttatgaaa aggaaaatat
     4741 gtatttatct cttttttcaa attctataag aacattcata ttaggttatg ttttagtatt
     4801 agtaatacta ttggtactaa ctatatctga tagtagttac ttaaatgaac tagatatgag
     4861 tagttattca aatggattaa atttatttac tatactccca caaatagcta gttatatgtg
     4921 ggcttttgca aatggaattt cagtaaccat aataaactca acagtatcaa tgtttacttt
     4981 aagttcttca tctttatttg gagatactaa attaatgttt tatgcaatgg gagcattgtc
     5041 tatgttaata ttattattaa atggatacaa gctaagattt aagtataata cagatagtat
     5101 aagacctata atagtattta gtatatatta tgcatttttg atgggaatat tggctttatt
     5161 tagtacattt atactagata gtaatattaa tttctttaat acaactaatt atggaacaac
     5221 tttaataatg caatttaaag tcttacaagc tattgtaatt tcatttgtat atagttttgt
     5281 gatatcttta ataggatata agctaaattc agctgattaa atatgattgg agggaatttc
     5341 tgtggaagga aatactaata ataaagtaga tgataaattt tctaaggtta agaaaaagtt
     5401 tggtagtgga aaatttaaag ttgaattata taaagaaaaa tcaaaattaa atagagagat
     5461 tgatgatatt caagaaaaga aagcaaagat attcttggaa atgggaatac tgacatatca
     5521 aaaaattaga gaagattcta ttaatgataa tagttttgat aaattctgtg atgagttact
     5581 agaacttgat aagttaattt atgaaaaaaa tatggaaatt aatgaaatgg aaatggcaga
     5641 aagtaatgta acttgtgagt gtggttatgt tggaaatgta aatgataaat attgtgctga
     5701 atgtggtaaa aaatttgaat tggaaaatga atgtgatgat tttataattt gtggttattg
     5761 tgaaagtgag atagatacag aggctgaatt ttgtccatgc tgtggaagaa aaattataat
     5821 ggatttagaa taatattggg aaacctatgt atagtataca tgggtttttt tattgaaatt
     5881 atttaaatgg acttataaca gtagttatat aaaatgaaaa taaacaccaa aaaaatgaaa
     5941 taaaatttct tttaaatgta aaaaacaagc taatatataa aataaatcag taaaaatata
     6001 gatgcgagaa aaaaatatga aaaaatattg caaagaaaaa gttttcatgt tattattaat
     6061 acataaatca agaaaataaa tttcagaaac gaggtaattt aaaaaatgct agataaggta
     6121 aagggaagat taatagtatc atgccaagct ttagaagatg aacctcttca tagtcctttt
     6181 ataatgggga gaatggctaa ggctgctatg gaaggtggag ctgttggaat tagagctcaa
     6241 ggagttgaag atattattga aataaaaaaa gttactggac ttcctgttat aggtattata
     6301 aagagaaact atgaagattc agatatatat ataacgccaa ctaaaaaaga agttgatgaa
     6361 cttttaacaa cagggtgtga aatgatagca ttagatgcta ccaatagagt tagaccaaat
     6421 aatgaagact taaaagaact tataaagtat ataaaagaaa acggtgttct agtaatggca
     6481 gatatttcaa attatgatga ggctatcaaa gcacaagagt acggtgtaga ttgcgtttca
     6541 actacactat ctggatatac tccatatact aaaacattag aaggtccaga ttttgtatta
     6601 atggaaagat tagttaaaga tttagaaata cctgtaatag ctgaaggaaa ggtaaatact
     6661 cctcaagatt taaaaaaggt ctttgagttg ggtgttcatt catcagtagt aggttcagca
     6721 ataacaagac cacaattaat aacagaaaaa tttgttaaag caattgaaat taattaaaaa
     6781 ttaatttata aattaaaaaa ttattatatt taactatatt tgaaaattaa aattggaggt
     6841 aaagatatga gaacaacaga tatgaaggga atttattcag cattattagt ttcatttgat
     6901 aaggaaggaa atataaatga aaaagggtta agacaaataa ttagacacaa tatagatgtt
     6961 tgtaaagtag atggtcttta tgtaggagga agtacagggg aaaacttcat gctttcaact
     7021 gatgaaaaga aaagaatatt tgaaatagct aaagatgaag tgaaagaaga aataaaatta
     7081 atagctcaag ttggttcagt taatttaaaa gaagctgtag aacttgctaa atttacaact
     7141 gatttaggat atgatgcaat aagtgctgtt acaccttttt actataaatt tgattttgaa
     7201 gaaataaaac actattataa tacaataata aattctgtag ataatagatt aataatatac
     7261 tctataccat ttttaactgg tgttgatatg agtttagacc agtttggaga attatttgaa
     7321 aatgaaaaaa taataggtgt taagtttaca gcagcagatt tctacttatt agagagaatg
     7381 agaaaaacat tcccaaataa attaatattt gcaggatttg atgaaatgat gttaccagct
     7441 acagttttag gtgtagatgg ggcaattggt tctacattca atgtaaacgg tgtcagagct
     7501 agacaaatat tcgaattaac taagaatgaa aaaatatcag aagcacttga agtacaacat
     7561 gtgactaatg atttaataac agatatatta ggaaatggct tatatcaaac aattaaatta
     7621 ctacttgaag aacaaggtgt tgaggctgga tactgtagac aacctatgaa agaagcaact
     7681 gatgaaatga aatcaagagc aaaagaaata tacagaaagt atttttaata aaatactttt
     7741 agtatgggag gattagtcaa atggtaggat ttacttggat agattttgca atactagtgg
     7801 tttacttatt ggcagtttta tttgcaggat tgttattttc aaaaaaggaa atgaagggaa
     7861 aagagttctt caaaggtgat ggaactattc cgtggtgggt tacatcagta tcaatatttg
     7921 ccacattatt aagtccaata tcatttttat cattagcagg aaattcttat ggtggtactt
     7981 ggattttgtg gtttgcacaa ttaggtatgt ttatagcaat acctttgaca ataaaatttt
     8041 tcttacctct atatagtagg ttagaaatag atacagcata tgaatactta gaaatgagat
     8101 acgaaagcaa aggtcttaga gtacttggag ctttgatgtt tataatatat caaataggac
     8161 gtatgtctat cataatgtat cttccatcaa tagttctggc tggtcttaca ggaatacctg
     8221 taaatgtact gataatagtt atgggtgtaa tagcaataat ttactcatat acaggtggat
     8281 taaaggctgt cttgtggacc gattttatac aaggaatggt attaatagta ggtgttacag
     8341 ggacattgtt ctatttaata gcaagtataa atggtggttt tggaacagta atggatactc
     8401 ttacaactgg acacaagttc ttagcaagta atgaagttat gtttgataaa aatatactat
     8461 ctacaagtgc atttataata tttgttggag ctggtcttaa tactttttca tcatatgtat
     8521 cgagtcaaga catagttcaa agatttacta caacaactga tataaagcaa cttaataaaa
     8581 tgacatatgg aaatggtgtt ttatcaatgg gacttgcaac agtattttat ctaattggaa
     8641 cttgtttatt tatatactat actcaaaacc cagatttagc tcaaacagtt caacaagacc
     8701 aagtatttgc atcatatata gcttatgaat taccagtggg tataacagga atactacttg
     8761 cagcgatata tgcagcttct caatcaactt tatcgacagg gcttaattca gttgctacaa
     8821 gttggacttt agatatacaa actatcataa caaaagatat aagtatggaa aagcaaacta
     8881 agatagcaca atatatatca ttaggtgtag gtatactttc tatagctgtt gcaatagtat
     8941 tagcaaatgg agaaataaag tcagcatatg aatggtttaa tagttttatg gggctagtac
     9001 taggtgtttt agcaggaata tttgtacttg gtgcattttg taaaaaagcg actaaaatgg
     9061 gagcatatgt tggattcata gtatcagcaa ttttagttgt ttatttaaaa taccgtatgc
     9121 cagaagtaac ttcttgggca tattctctaa taacaatcac gacttctgta gtggtaggta
     9181 caatagttag tgcaatagaa gctaaagtta aagcaaaagt atctttacca aaagctgaga
     9241 ctactgttta ttatgaaaaa taatatttaa atgataaatt gtcttataga gtgattagat
     9301 aaataattta gttactctat aagattgtat aatatacttt gtatataaaa gtataaaaat
     9361 agactttata attatatagg gagatagtgc ttatgatatt tggaaatata aatcatagta
     9421 agacatattc aacattgcat gaagatttac ttagatgttt tgaatatgct aaagataatt
     9481 cattaataga ttatgaaaaa ggtacttata caatagatgg tgatgatatt tttgtgaata
     9541 ttgtagagta taaaacttgt gaaaaagaag atagattctg ggaagctcat aagaagtata
     9601 tagatgttca tttgatgctt gatggatgtg aacgaataga tataaatttt atagaaaatt
     9661 tagaacaaaa aatatatgaa gaaaagggcg atttcttgcc tcttgatggt aaaaataatg
     9721 gatacatgga acttagaaaa ggtgattttt tagtttgtta tccggaagat gctcatatga
     9781 caggaataaa agttttagaa aaagaaaata tcaaaaaagc tatttttaag gttttggtta
     9841 gataatgata atttatataa ccactagggc tgaaaatagt gatttaactt tcagcgatta
     9901 gtgagacttc gtaaatttta gttagattac tattttcagc cttagttttt tatgagaaaa
     9961 ttgaaaataa ttaaaagctt aaaattttgt aaaggagtta acttatggaa aatatagatg
    10021 tattcttatt aataggacaa agcaatgcta gaggattggg aaatccaaaa gagagcatca
    10081 ttccaaatga aaattgtttt gaatatttga gtactgatga aattataaat atgagatgtg
    10141 agctagagac ttcagaaggt gatggtacta tagcacctgc attttcaaat gaatggaata
    10201 agcttactgg aaataaagtt tgttttattc acaatgcaaa agatggttca agaataaaaa
    10261 actggaatca tgataataac tggtttctaa atgacactat agaaaaattt aatacaggct
    10321 gtactacctt aagtaaacat tataatatag aaaataaata cgttatttgg attcaaggtg
    10381 aaagtgatgc aaaatatggt agtgatgtat tgtactataa agaaagtcta aaaaaaattg
    10441 cgtataggct taaagaagaa tgtatgattg ataaaatgtt tgtaagttta actggttatt
    10501 ggcttggaga agatgaatat tttattagaa caagacgaat tgcagcagca caggagtcgg
    10561 cttgtagtga atgtgatata ttatgtgtag gaagcaaaat tgctatgcag tttcatgaca
    10621 gaggattaac tattgatgat gttcattaca ctcaagaagg tcttaatatg ttaggagagg
    10681 acttatgtaa aaatatttat aagtatcata taaccaaaga aaaaagtgta ttaagtgata
    10741 ctatagactt atcagaagca aggaaatata tctgtgaatt ggaaaagata agtaaaagat
    10801 ttgtgtaata taaaatttta aatagagttg ttaatttata aaaataattt gtatggagat
    10861 atgttatgaa aaattacgtt tgtatagatg ttgggggtac ttcaataaaa tatggtttta
    10921 ttagagaaga tggatttata attgataaat caagtcttga tactgaagca aaggaaaaag
    10981 gtggagaagg aatattagcc aaaataaaag atatagtaaa aaaatatata gaggaaaatg
    11041 aaataagtgg tatatgtata tcaactgcag gtatggttga cccagttgaa ggtaaaatac
    11101 tatttgcatt agaagaatta attccaaact ataagggcat gcaattaaaa aaagaagtag
    11161 aaaaagagtt taatataaaa tgtgaagttg aaaatgatgt taattgtgct ggacttggtg
    11221 aaatgtggct tggagcaggt aaagatgcaa catcttctat atgtttaaca ataggtactg
    11281 gaattggtgg atgtattata ataaataata aactgataaa tgggtttagt aatagtgctg
    11341 gtgaagtagg atatatgaat gtaaatggaa gttcttttca agaattggca tctactagca
    11401 gtctaattaa aaaagtagca aaaataaaaa atttgaatga aaatgactta aatggaaaaa
    11461 taatttttga tttagcaaag aataatgatg aagattgttt aaaagaactc gataatatga
    11521 taaaatcatt agcagttgga atcgcaaata tatgttatgt aataaatcca gaagtggtaa
    11581 ttttaggtgg tgggattatg gcacaagaaa agttcctaaa accaaaaata gacaaagcat
    11641 taaaggaggt tcttatagag agagtttaca aaaacactaa tatagaattt gcaaagagac
    11701 aaaatgatgc aggaatgctt ggagcattat ataatttttt aaacaaaata taaagaatag
    11761 aagggttttt aatgagtatt ttagaacaat tggaatcacc aacttttaaa gtcacaaaat
    11821 cagataaatt attaatagct tatataaaag aaaatataga tgatgtattt tataaaccaa
    11881 tatcacaaat agctaaagag agcaatattg gtgaagcaac tataactagg tttgtaaaaa
    11941 aaatgaattt taatggatta caggatttta aagttacttt agcacaagaa atatcaacta
    12001 tcaataaaaa aaatattata aataaaaata tacaaaatga tgagccagct ttggatacag
    12061 caaaaaaact tttaagttca aatgtaacca ctttagagaa cacagtagag ataatcaata
    12121 gtaaggatgt acatgactgc gcaaggctta taataaatgc aaagaaagtt tacttcatag
    12181 gtattggata ttctggtata atagcacagg attcaaacta taaatttatg agaataggtc
    12241 ttaattgtgt aagttttgac agtagtcata caatgataat gatgtcttcc ataatggaag
    12301 aaggagattt aataattgca atttcacatt ctggtgaaac agaagagatt ataaaaactg
    12361 taaagcttgc aagagccaat aatgctaaaa ttatatcaat tactgaaaat aaaaattctg
    12421 aattaaagga tatttcagat gtacacttat cttatgtatc gggagaaaca gtactggaaa
    12481 ctggttcaat atcttctaaa ttagcacaat ttttcattat tgatttagta tatacacagg
    12541 tagtaaaaga actttctaat gaagctattg aaaggaaaat taaaactaca aatgctataa
    12601 aattgtttaa aaatgaataa aataagaaat ttgtaatgtt ttatagagct ctcttaaaaa
    12661 tttaggaatg gagagatatt acatgtctaa attaaaagat tataatattg ataaagtaat
    12721 aatttttaat aatttaagta ctaaaacgaa gaatcaactt aaagaaaaag ttaaactaaa
    12781 aagattacaa aaaaaagaaa ttttatttta tgaaaaagat agcttagaca gtgtttatat
    12841 acttttagaa ggaaaggtat ctatttttaa gataagtgaa aatggagaga gaaaagtaat
    12901 tttcatatta aatagtgggg aagtcataaa tgatattaca cttgacgctt ctaaaaactc
    12961 tactgttggc tgtgaagcat ttgaaaattc aattgtagct tattatagta ttgaagaatt
    13021 tttagaaatt atgcaaaatg attttcaact tacaaaggat attatttctt atatggaaag
    13081 aagaataaga cgtttatata gacagttgaa aaattctata tccataaaag tagataaaaa
    13141 acttgcagca aaattatata ggttaagtag agaatttgga gtttgctgtg gagaatggac
    13201 tttactaaat gtaaatatta cagttacata tttagctgat atgcttggct gtaaaaggga
    13261 gactgtttcc agaatgataa aggtattgca aaaagaagaa cttattaaaa ttgacaataa
    13321 aggtttttat gttaaagaaa ctgaattatc aaggtatttt aaaaataatt aattatgatt
    13381 aagtaagagt attattagaa ttttaattaa ataaaaatat tattaagaga atctatttat
    13441 agattctttt ttattgtcta atttattaat ttttatttta ccctattgaa ttgtataaaa
    13501 aaacaaataa gattcttttt tattcaaaaa attgagtaga tagtagtttt attgtactta
    13561 atgattgtat ttaagtgatt agatttgaaa tcgaataatg tagataataa aaaaatatta
    13621 acagaactta ataaactcca ttaatatttt ttttattatt tttgaaactg tgataattat
    13681 cacggaagca tagaaaataa agtgttaaga tttaaacaag atagcaagta agtaaaacta
    13741 aaatataaga aaggtgataa aaatgaaact aaaattagat tcatctaagt tcaatgaagg
    13801 tctgaattat ctaaaaaaag actacaagat atttgcacca gttttaatcc catttaaagg
    13861 tactttttca gatactgatg ttataagata caaggaggta aacgcttttg aagaaatgga
    13921 atttgctaag aaagcaaact tttcaccaaa agaagttgta cttcccataa atcaagtatt
    13981 gttttatttt actgaaaaag agtttaagga aagcgattta gacaacaaga aaattttaat
    14041 tttcttaaga gcttgtgaca taaatggtat aaaaagactt gatgaaatat atctaaataa
    14101 tggtgaagaa aaagattatt tttataaaaa tatcagagat aaagtaaagt ttgcacttgt
    14161 agggtgtaag gaaagtttta gaaactgttt ttgtgtgagc atggattcta acaaaactga
    14221 taattattca attggattaa atatagaagg agatacactg tacttagata taaaggatag
    14281 tgaatttgaa gtatttaatg gagaagcaac tgaatttaat gttgattatg taactgataa
    14341 tttaatatct gtagatgtgc cagagaatat tgattcaaat gaaatgatag gaaattcaat
    14401 atgggatgaa tatgatacaa gatgtatagg atgtggtaga tgtaattttg tatgtccaac
    14461 atgttcatgt tttacaatgc aggatatttt ctataaggaa aacgaaaatg taggtgagag
    14521 aagaagggtt tgggcttctt gtcaagtaga tggatataca gatatagcag gtggaaattc
    14581 ttttagaaaa aaacaaggcg aaagaatgag atttaaaact atgcataaaa tacatgattt
    14641 taaaaaaaga ttcggatatc atatgtgtgt tggctgtgga agatgtgatg atgcctgtcc
    14701 gcaatacata tcattttcaa agtgtataga aaaaataaat gatttagtaa ttagtaagga
    14761 ggaagtataa atgaacccat atataccagt aagtgcaaaa atactagata tagttaaaca
    14821 tactgataaa gaatggactt ttagagtaaa ctgcaataca aaaggtgtat tgcctggaaa
    14881 gttttatgag atatctatac ctaaatacgg tgaaagtcca atatcagtat caggatatgg
    14941 agaggattat attgacttta caataagaaa tgtaggaaaa gtaactagcg agttgtttaa
    15001 ttataaagaa ggagattctt tttttataag aggtccttat ggaaatggat ttgatgtatc
    15061 cctttatgaa ggaagagaaa ttgtagtagt ggcaggagga agtgcattag cccctgtaag
    15121 aggaatagtt gaatattttt ataataataa agaaaaatgc gaaaagttta aattaatagt
    15181 aggatttaaa tcaccaaaag atattttatt tgcagatgat ttaaagagat ggagtaaaaa
    15241 acttgatatt ttagttactg tagatggagc agaggaagga tatagtggta atgtaggatt
    15301 agtaacaaaa tacataccag aattggatat gaaagatata aacaatactt ctatagttgt
    15361 agttggacct ccaatgatga tgaaatttac agtagaagaa tttttaaaaa gagatttaga
    15421 tgaaaagaac atttgggttt cttatgaaag aaaaatgtgt tgtggaatag gtaaatgtgg
    15481 acattgtaaa atggatgata cttacatatg tttagatgga ccagtatttg attattcata
    15541 tgctaaaaat cttattgatt agggggtgaa gtttgtgata agagatttaa ataccaaaaa
    15601 agtaatgaaa aatgcttata gaattacaaa aacaaaatat gagacttctt taagagttag
    15661 agtacctgga ggtcttattg accctgagag tttagctgta gtttctaaaa ttgcaagtga
    15721 gtacggcaat ggacaggtgc acataactac aagacagggg tttgaaatat taggaataaa
    15781 tatggaagat atggaagaaa taaataaaat tatacaacct gttattgaaa aaatgaatat
    15841 aaatcaaagt gagaaaaacg caggttatcc agcagcaggt acaagaaata tagcagcttg
    15901 tataggaaat aaagtctgtc caaaggctca atataataca actgaatttg ctaaaagaat
    15961 agaaaaagct atatttccaa atgatttaca ttttaaagtg gctttaactg gttgtccaaa
    16021 tgattgtata aaagctagaa tgaatgactt tggaattatt ggtatggctt taccaatata
    16081 tgaaaaggat agatgtgtaa attgtggagc atgtgtaaaa aaatgttcta agatatctgt
    16141 tggagcatta aaaacagaaa ataataaggt ggtaagagat aaagataagt gtataggctg
    16201 tggagagtgt gtgctaaatt gcccaacaaa tgcatggact agagatgaga aaaaatacta
    16261 tagattagct ataatgggta gaacaggaaa gaaaaaccct agactagcag aagattttct
    16321 tttatgggta gatgaggaca gcataataaa gataatactt aatacttata gatatgtaga
    16381 aaagtatata gataaagatg caccaggagg aaaagaacat ataggatata taattgatag
    16441 aacaggattt atggaattta aaaaatgggc acttgaaggt gtagagcttc cagaaataac
    16501 taaaatgtac gaaaacatat actggagtgg aattaaatat ctataaattg agtaaaacat
    16561 atatttgaat aaattaaaat ttaatagaag gaagagggaa ttatgcataa agaaactttg
    16621 gataaattaa ctaatgcagc tataaataag ataaatttat taaacacaag taaagtaaaa
    16681 tatttggtat cttctgcgtt tgcaggactt tatgtaggta taggtatact tttgatattt
    16741 actattggag gacttttgac tgatgcaggt tcacctatga ctaagatagt aatggggtta
    16801 tcatttgcaa tagcactaag tttggttata atgacgggaa cagagttatt tactggaaac
    16861 aatatggtta tgtctgctgg tatgttaaat aaaggtgtaa gtataaaaga tacttctaaa
    16921 atatgggcat acagttgggt aggtaattta atcggagctt tggttttagg cattatattt
    16981 gtaggaactg gtctaataga caaaggacct gtagctgaat tttttgcaaa tacagcagct
    17041 agtaaagcat ccatgccatt tacagctctt ttctttagag ggattttatg taatattcta
    17101 gtatgtgtat cagtgttgtg ttcgtttaga actaatagtg atactgcaaa aataattatg
    17161 atattcttat gtttatttgc ttttataaca tcaggctttg agcatagtgt agcaaatatg
    17221 acaatttata gtgtttcatt attttcacca acaataaata cagttactat tggaggagct
    17281 atttataatt tagtagctgt aacacttgga aatattgttg gaggagcttt atttatgggt
    17341 cttggaactt atatattagg taaagaaaag cttaattaaa tttattgtat aaattataac
    17401 tctcttgata aatgcatttt tagtattgtt gagagagtta tttttatatt tttgaaaaaa
    17461 tatttgaaac aaaaaaaata tgggagcata cgaaaatata tcggttatat atataaaaaa
    17521 tacgtttata tatgaattat atagttctaa atataaaaaa agttaaagtc ctaccgtaaa
    17581 aaagcgcatt ttgaataaga taacaaatat gataaaattg gtcttgttga aatttttagg
    17641 ggggatatga tgacaaagaa actagtaata tcaaaaacaa agttgtttat ttttataata
    17701 gcatttattt ctatatttat atatttattt ggaagtaaaa atacacttat aggtgtaggt
    17761 atagtaacag ctatgctaac gctcttggaa agagatttaa ctatttctcc aattaaaaat
    17821 ttactgaagt atttagcaat aaatataatc ttaggaatac tatcattttt tgcagtacaa
    17881 aatatgtatt taggagtttt attaaatttt atagcattat ttataatagg gtatgtattt
    17941 agttatgact taaaaagagc agtatatgta ccctttggtc taatgtatat atttatggta
    18001 agtatacctg taggaaaaag tgaatttcct atgagattgt cggctttagc tgttggagca
    18061 gttataataa tgattgctca atttgttatg aatagaaata ggatgaaaaa tgtcggagat
    18121 aaagaactga tatctatatg tgatgaatta ttagaaaaaa ttagtctttt aaaaaatact
    18181 attaatgatg atagttctat aattaaatct agtatgagaa aaatagatag ctgtaattat
    18241 agaataaatt ctatatctaa aaatttgaaa atggttattt ttgataatag aaaagatgac
    18301 ttttatatca gtattagagg tatagacata atgaatattt tattttcatt agaaagaata
    18361 agtttaatcc tagaaagata caaaaaggat agtaaagaat ttgaagatga agatataaaa
    18421 aatattttag aagaaagtag cataaatagt aaatcagatg ttctagttgt agcaacgaaa
    18481 gaaataaact atattaagat gtgtttagaa aataaagata ccataactga taaagagata
    18541 ttaggattta gagattatgt tattgctcag gatactaaaa atataaattt aaaagaaatt
    18601 tatagtgttt tagaaaattt atatgagttt ttagtagatt ataaaaaagt aaaatcaaga
    18661 gacgaaaaga aagctgaaag aaaatcaaag atacctcatg aatttaaacg actatcaata
    18721 tataagaaaa actttaattt aaattctata agattttctt atgcagtaaa gattgcttta
    18781 gctacagctg tagcgggttt tattatggat tatttccatt taagagatgg aagatggata
    18841 atgttaactg tcttttcatt aacacaacct tacgcagaaa attgtataca aaggtctaga
    18901 aaaagaatag aaggtacatt tataggagct gtaatattta ttgtattatt ttcaataata
    18961 aaagatagta cattaaggtc gttaatagtt cttttagcag ggtatataaa ctcttatgta
    19021 gttgattata gaaaattaat ggtatgtgta actgtttcag ctcttggttc agcagtagtt
    19081 atgggagacc caaatgtttt aaccataagc aggatttcat atgtagcatt aggagcaatt
    19141 attgcattaa tagtaaataa gtttatatta ccatatgatg ctaaaacagg ctatcaacat
    19201 gttatagaaa tgtataaagg aatagttaaa aatataattg atgaagtcaa taagtctata
    19261 gaaaatgtag ctgatgttta ctatataaaa aatttattat tgataccatc acttattgaa
    19321 gatagactta tgttgataaa tgctatatat aaagataaac atcaagagga ttttttagaa
    19381 aatcagaaat tactaataag taatatgtat aatctatata taaatgttaa taaaaataaa
    19441 ataaaagatg aagatgttga aaaaatattg agagatacta attatatttc aaattacaat
    19501 gtagataagt atgatgaagg aagaagtgta attttagaga gtattataaa tactaaaagt
    19561 ctaggtgaca agataatatg tctaaactta ctgcaaactc taaatggtgt caaagaaatg
    19621 tatagaataa gtaatataac taaagtttca ataaaagaag cagcttagat attaaattat
    19681 agaatagcca tatatttaaa ataaagtata tggctatttg ttttataaaa tactaaaaga
    19741 aaataatata taaaaaacaa aaaacatata tttatgaatt ttatatgaaa atagttaaaa
    19801 tattgatttt tttcattggt tgaaaaaaca atttacttag gataaactat aatagtattc
    19861 aaatattatg ggggttagat ttatgagtaa agatgtaaag gtaaagcgta ataagaaata
    19921 tgatacattt agtataacta tggaacttga gagaccttta ctttatgatg aggttgagaa
    19981 caaagatgat aaaaataata atagaaaatt taacataaag aataagatat ttaagggaat
    20041 aggtatacta tttgtattga ttttgcttgg ctttttcata tggataaata aaacatatga
    20101 acctcaaaag ctggcaaaag aagctctagt cagcaatagt aaagttgaag taactgtaaa
    20161 tgaaaacatt tcatttacac caaaaggaag aaaagtttct aaaggtttaa ttttgtatcc
    20221 aggagctaaa gtagaaatag aatcttatgc tccacttgca agaaaaatag cagaaagtgg
    20281 atatgaagtt gtaatcgtaa agatgccact taatctagct atacttggaa ctaataaggc
    20341 acagaaagtt atggattctt acaacaacat agaacattgg gtaataggag gtcattcatt
    20401 aggaggagtt gcagcatcaa attttgcacg tgataataaa ttaattgaag gcgttgtatt
    20461 tttagcttct tatccaatgg gtgatgagtt gaaagaatta ggaaaaaaag ttatatctat
    20521 atgggggagc aaagatggag tagtcaattt taaaagtctt gtagaatcaa aacaaaaact
    20581 tcctgatgat acaacttatg ttgagattga aggaggaaat catgcacaat ttggagatta
    20641 tggaaaacaa aagggagata atgatgctat tataagtcaa gaaaaacaac ttaatattac
    20701 tgccaatagt atcattaaat ttttaaagaa tatatcttaa actaaaattt aaaaaatata
    20761 attttataag ttattattta aagtaaatat taataatata atagaatgaa tattttatta
    20821 caagggggat tttaatatgg aatacgatat gccactttac agaccaccaa gtgaggctta
    20881 tagtcttata atacaagtca cactaggatg ttctcataac aaatgtacgt tttgtagtat
    20941 gtacaaatct aaaaaattta aaataaagcc actagaagta ataaaaaatg aaattgatat
    21001 atttagaaga tattataagc atgtagaaag aatattctta gcagatggag atgcattgat
    21061 aataccaatg gagaaattaa gagatattat tttatatata aaagaagttt ttccagagtg
    21121 tgaaagaatt actatgtacg gctctcctaa atctatagag aaaaaatctg atgatgaact
    21181 taaagaatta agaaaacttg gtgttaaaat gatttatcta gggcttgaaa gtggaagcaa
    21241 tgaagtatta gaagatatta agaaaggttt tagtagtgaa caattaataa aagttggtag
    21301 aaaagttaaa aaaagtggga ttaaattatc agccactgta atagcaggtc ttggaggaac
    21361 taaaaaaaca catcagcatg cagttgatac aggaaaaatg ctaggagcaa tttcaccaga
    21421 ttatgtgggt gtacttagtt taatggtaga acctaatact gaactttacg atttacttaa
    21481 ggcaggagag tttacaatac tagaggataa ggctgtgtta caagaaatta aagagatgat
    21541 aaagaatata gatgctaatg aaaaaattgt atttagaagt aatcatgcat caaattatgc
    21601 taatttaaaa ggtgtattac ctgatgataa acaacgtcta attgatgaaa ttgattacta
    21661 tctaagtaac caaaagctaa aaagagaaga atatagaaga ctatagtttt tgatatatca
    21721 atctatactg ataggtaaat actaagatta tttagataca aaaaatcatg ctacattaat
    21781 agttgcttac tattgatgta gcatgatttt ttattaaaaa acaaaatggt atattcatat
    21841 ataatatatc aataataatg aaaatgtgaa ctagtttaat agaattttac ctattataat
    21901 aaaaacagga atttaaataa taaaaagtaa agtaactttt tattaagtaa ctttactttt
    21961 tattttattt aatgttgtat taaatttata tatattaaaa taatatacaa attttgaaaa
    22021 agctcttata aaatgattat taaagtaaag tttaatataa ataaattata aaatattaaa
    22081 ctaatttatc aatatttcct gattgaatat gcttaatgtt tgattgaatt tttttatatg
    22141 gccaatccca ccatttaatt tctaataatt ttgaaattgt atcattatta aatctctttt
    22201 ttataatttt tgcaggtact cctccaacaa tagaatacgg tggaacgtca ttagtaacta
    22261 ctgctcttgt tccaataatt gcaccatcac caatatttac acctgacata attatagaat
    22321 cataacctat ccacacatca tttccaatta taatgttacc cttattgtcc caagcgtccg
    22381 ttatatggtt gatatcgagt ttccattctt cataaaagat gggaaaagta tatgtggatt
    22441 ttgatttcat tgagtgattt ccactagtca ttagaaattt tgcattacat gctattgagc
    22501 aaaacttacc aattattaat ttatcattgt ttatagggta atgatacaat acattgtttt
    22561 tctcaaaatc tcttgggtca ttataaaagt cattatatat tgtgtaatct ccaacttcta
    22621 tattttccct tgttattaca tttttaagat atacagtttg ataatcatta cttcttggat
    22681 ataccttatt tgaacttgga atagtcatat ttaaatctct cctttaatat atattatgtt
    22741 tttgactatt ccactactac aatacatctc ttcacagaat cactccttgt taagaatctt
    22801 cataagataa tggcgtcctt ttttagtgtt aagtcggata ttctttctta gtccattctt
    22861 tttagcgtat aactgacaaa ctgtcatttt cttaccaata gtgtcaatgc tatcatcaag
    22921 gtcattttgt attgcttttt ccttatccct taatgatata tcatcacgtt ttccctttgg
    22981 gggtttatca gtaggtacaa gtttccaaga gtaaacaaat tgtggtttac caaatgaata
    23041 tacatactta tatgcgtatc ttccatcttt tctctggctc tctccagttc ttaaaattct
    23101 atctttatta tctcgtcttt tttcagttga catgataaga agctcctctc aataaccgaa
    23161 ttgagcttga tacgtcatat gaatattata acatataagg ctcaatttca ttagataacg
    23221 tcaagtgtat caacgatttt ctcaaattgt tttctcttta tttgaatgcg attgctattc
    23281 ataatgaccc agccagaatc aaggttttca tcagcacgtt tacgtaattt tttctctcca
    23341 atacgaaagt attttgacgc ttcttcaatc gtcaaggtat atttttccca aataggtaca
    23401 tcagtattgt tcatataatg tatcactcct ttctatgttc gtagttcaga agtagataga
    23461 tggctttgat aagctccatt ggtatttcaa ccaatcccat tcttatggac agaaccgtgt
    23521 catacaggtg tatcattata ctgtggtaca ggttacggca aaacaaccgt tccaaaggtt
    23581 attcacaaat cactatatag tagctctctt gattaaggtc atggcgtata gtatttgttg
    23641 gctatctgta tcacaaacgt atctatctac tttattcagt tgtcaaagaa cagtcggcat
    23701 tgatttgcct ataaaaaatc acaatagctt gtgggctttt atagacaaat aattagtgat
    23761 tctccatgta ccaaatagct tgatacatgg agagagggcg agattaagac aaattaaatc
    23821 tcaaaatagc agtgattagt tttgttccta gcattcgctt tgtttcttct tctacatgaa
    23881 tatagggatt tccgtattca tcaaataaag ttttctgtga aagacgaatg atatagtgtt
    23941 caaaatgttt aagtattacg tttattgcat ttacatcgcc atgtacagca agtaaaataa
    24001 ttgtaaaagg taatacttct ttagtaggtt tcatttcaat gttcctgcat gagttctttc
    24061 aactctttta gtgcatttgt tttgtgataa tgtatggtat tttctgctaa atccatcaat
    24121 gttgctatgt cagcatttgt catgttgaaa aagaatgaaa gtagaattat atcttgtttt
    24181 ctttttgtaa gttttccgat tgcttgcgcc attaatacat cttcaattcg tatgttgtag
    24241 tcgtaagaaa ccatacagat gtagttagaa tcataatcat ctaaaatact caatttactt
    24301 aattctgcaa gtgacaaaga ttcgagagat accaaataat catttctgcg tttattttcg
    24361 tcataaatat ctctagcata gttacgcaaa actgttttac agaaactgtc gaattgatgt
    24421 tcaattgtct tttcatcaac cataagattt caccctcttt ccatcgcaag gagttaaata
    24481 accttgctta ctcctatcac ggtgggaggg cgttaaatct tcgataaatt tcaaaaaaaa
    24541 gagaaaaaaa tacacactct gcctataggg caaaaatgtg tattctttaa aacgtattta
    24601 atttatattg gttgtaagcc accaccatat tgatgtatgg aaatatgcat tggctagctt
    24661 ttcataaaaa tacaaagatg cataagaaat taatagaggg gaaaaactta ttctgttatt
    24721 aaaaagtagg ttaattctaa taaatgctat tgcggtcgaa ttaaactata tacatggcaa
    24781 tcaatcatgt ttctattctt tattatgaat tgtgacagta ttcttcaatc ttaaagccac
    24841 atttttccaa tactttactt gactctctat tgtaggaata tacattagca tgaattttgt
    24901 taaggttgta tttttcaaag gcaattttgc atatttcttt tactgcattt gttgctatcc
    24961 ctttgcctca atagttccta gcaagccagt aacctaattc agcattttta ttaatagagg
    25021 tatcttcttc aaatgttagg ctgatacttc caatagccct ttcttgataa aaaatagcat
    25081 agctaagttg tttaacatct gaagttgcca aacaaaaact aacaaaatct ctagcgtttt
    25141 gctccctata agggtggggg aagttgtcac gaagattctt tgcaatttct ttatcattcg
    25201 caaactcaac taaatcggta atataagcat aattccactc tataagttcc atttttcttc
    25261 tccttttatg aaacagctac aagaaatctt tctaagccaa taccacttat caaacagcgt
    25321 tctcttttat ttccaagcat ttgataagtc cagtcaacaa atccaccgtc aactatttca
    25381 acggtttcat ttccttgttt gaccgataat ttgaaattga tacctttata ataattatta
    25441 tcaacatcat cattatgaat tgataactct atattaggaa aaataagttt gatagtttca
    25501 accattctgt cgaaaaatcc gtcattatct ttgtatccgt ttcttttgcg tagaataata
    25561 gagaaacgaa cattttctat ttcacttaat atatctttat aatagtttaa gtgcttttct
    25621 aacaacattt tttcacaagt gtaagaccct gtatctatac cagatgaaac catacaatat
    25681 aagccaaaat gtgaatataa acctttacct acaaaatttt gtgctcttat taccctagca
    25741 gtagtagcca tgtggatagg tatggtatta ttttcttctt ttctttttaa tttatcagca
    25801 ataattattg ccaacatatt tgaggggtct gcaagtgttt ctgtccctcg tagagcactt
    25861 actacgttat attgatctac ggagccaaaa acgctacagc tacctaatgg ggcagaggga
    25921 gaaagcataa tcgtcttgat atccatattg aatgcttttc tcaataattt tgattccaaa
    25981 gcatgaattt cttctggatc tataccgcta gggatagtaa atctatttag ttggtatgac
    26041 tttagaatat cagttgcagt taaagtattt gcttgtctat caaacacttc taatagaagt
    26101 gagttcaaat ctgattttga tagagctgat aacttatcaa ctatattctt atccccaatt
    26161 ttatttgtaa ttctacttaa aatatcactc atagttatcc tccatactgt tactttcaaa
    26221 ataattatag aattgttaca acaactaatc taggtcattt gaccaaaaat gaaaaaacac
    26281 tgaatattta ctattcaata tttttttact ttgggtttat ttgattaaat cttgaaaata
    26341 ctgtaatgca accctttcag cttcaacctt tcggacaata ggactttgtg ataattcctc
    26401 tcttaactca agatacaggt tgatagtagc ctgcaatgca ttaacacagc ttttatattc
    26461 atggttagca accgtctttt ctaatgcttc aatatattgg ggtgcgtcca attcaatttt
    26521 tctaactcca cgaggtaatt tacctaagag aagctgtatt aatggggcaa gtactgattg
    26581 tcttaaaaaa gataaaaaat caattgtttc aaatagttct ctacgtccaa tcttagtgca
    26641 agcgtaatga acccaaatcc aaaatctatc ttcaatccac tgtaagtctg gagttgggaa
    26701 gtatgcttct tttttagaat aaatttctgt tatgcagttg ttttcttcat agagaatagc
    26761 tgaatcttca accctatcta gtaaaccatc taaggttgta aacttaaaat caacatgaag
    26821 aacaggggaa tcatagaggg aaattatcaa tcgaggttct ccaacgtgtt cgccagtaaa
    26881 agcagaaact aatgttccaa actgttccac aataagtaat ctctcttcga taacttcttc
    26941 ataggattta tcatctgcta caatcagaaa atccaaatca gaatattcat ctaacgattt
    27001 tgtgatataa gaactgctaa ttgcaagtcc tattatccta ctatctcttt ttgaaaattc
    27061 taatacgttt tgtatcattt tctgttgtgt tttagtcata atataacacc tctcactgtc
    27121 ttttattagc tatcaatcca acataattat gcataggagt attatataat gaagaaataa
    27181 aaaaaaatag gtcacttgac ccgaaataaa aaagcattga ataattatta ttcaatactt
    27241 ttttgaaatt atacttatgt tgtaggaaga ttctttaata cctctcgctg attaattaca
    27301 ctaaatcttt tgttttcata agcaattaga tgttcttgta cacattcatt tatagcacga
    27361 ttaatgcttc taattggagc gtttacttcg ctagcaagct gttttttggt aagcagattt
    27421 aattcacttc tataatagtg taaggatata cacctcagaa gtcgttcttt aacacttaaa
    27481 gatgataatt cttcaattaa ttcagcattt acaactaatt tactagatat ttctcgaatc
    27541 agaaattttg tagcttcaaa atctcccctt aaccagttta aaaaatcatc tctatgaagt
    27601 ttatatacat tacaatctgt gaaagcgaca atttcaacgg gttttttccc atcattaaat
    27661 tgttccattt ctccaaaaaa actaccactt ctataaagat gaatcgttga gatgtttcct
    27721 ttcacattta agatgaatgc ttctgcaata ccgtcaatca taagaattac atattcattt
    27781 tcttgctcag caaaaagaat agtctctttc tttttatacg tttttttaac aagcttcttt
    27841 ttaatatctt cattcataaa atcaattaaa tgcatattca tccctcctta ccaaatcttt
    27901 gattaaatta tatcatcttt caattagtta ggtaagatag taaaaatata tttacataga
    27961 aactattcca ttattatttt ccagttgtca tttttctgca aaaacttatc actgtcacga
    28021 ctggagatac cagtaaggaa tgttaggata tcaatcgcta aactttcaga atccttttta
    28081 cggctcaaaa tgacgtaagg gtcaagcaat cctttgtttt catcattact ggttaaattg
    28141 acaatgttta tctcatgggc tatttctggt agcgtttctt tccatttgcc gcgttctgct
    28201 ttagggtcaa ctatgaccgc ctgtccgccg aatagtaccg catagtaaac aagcatattg
    28261 ttactgaata atttaccacc acccaatgaa ccgataaacg cagacgctaa cgcattggta
    28321 atagaaccct ttaccccttg actagcaagg gcaggtttta gatagacatt ctttccagtg
    28381 tccagattgt agccaagata gatatcctca tgttcgccaa gggtttgtgt cgctccaaaa
    28441 ccaagtccag ccaaaaaatc cgaagtgaca tattgaatat aatcattgat gtaacgtttg
    28501 ctgacaggaa taaattcgcc atgcaatccc aacatatccc caaagggacg cacgagcttg
    28561 attgataagt cgtcgtaaaa gtctttgact tcatcacaac gcctttttag ctcgtcaaga
    28621 ttctttgtag atacacggac aacatagcta agtttataca tagattcttt acagttaaaa
    28681 gtctgttttt aaaaaaatgt ataaattata aatcaaaata tagatactat caatgaccca
    28741 ctaggtgcaa aaagcattga tatggttaaa ttatcagacg ctaaaagctg ggctatccga
    28801 atgagtgaag atgggtgtgc ttataaatcc attgacaatt ataagcgctc actgaaagcg
    28861 tcgtttttca tggcaattca agacgactgt attagaaaga atccatttaa tttttagtta
    28921 agtgatgttt tggaagatac aacagaacca aaaatcgctc taacaccaga acaggaaatg
    28981 ggcttattat cctttatggg gagcgataag acttattgta aatattatga tgatgttgtt
    29041 atcctcttag aaacaggact acgcatttct gaattatgcg gtttgacttt agaattggat
    29101 atgaaaaata aagccattat ggtagaccat caattgttga gtgatactaa gattggctat
    29161 tatgtagaag ttccaaagac cacacagggt aagcgagaaa ttccaatgac tgaaagagct
    29221 tatcaatcat ttgaacgtat cgtggaacgg cgtaagaacg ctaaagcaga accaatcatt
    29281 gttgatggtt accagaactt cctatttctt aaacaagatg gattaccaaa acaagcaact
    29341 cattatcaaa gcatgttaag agcgttagtc aagaagtata ataagaccca tgaggacaag
    29401 ctaccaaaga ttacgccaca tacctttagg catacactct gtacaaatat ggctaacaaa
    29461 ggaatgagtc ctaatatatt gcaatatatt atggggcata aaaacattac tatgacgctt
    29521 ggctattatg cacatggttc atttagttct tcgagagctg aaatggaacg gttataatcc
    29581 tagtagtatg actagagttt actacttatt tactactttt gatggcattc ttatacggtt
    29641 aaatgccaac ttatgcaaag tatcttccaa aaagaaaatg ccgatactcc ttgtagatac
    29701 aggatatatc gacatttacc aacttatgaa aagataatca aatttaatat aagtttttca
    29761 aataaaaaga taccaaattc tttttcgaga atctatataa cattacttaa gcttggttgg
    29821 ggtataaaca attgagtagc tacttttgta tggtgttcaa ctttagtcaa aactcttaag
    29881 taatgcaaat gatttagatt cattaatatt caatctcttc ataagtagtg aaattcgagt
    29941 tatttctgca taattatact atgatttata gattaattct attagcatcc agaataatat
    30001 tgtttatatg agtaaaattt aaagaatatt gtgaaaatta taggatgtta aaataaattt
    30061 aggtaaaaaa gaagtgtttg tatattatag agtacctttt ctaaaatatg tgggattgtt
    30121 ttaagaatta gaataaaaat tatttttaaa ttagtatttt tataatgtat agtattttta
    30181 atgtataatt aaattgtgca gaaaatagaa tttaaagtcc tatagaattt ctgattatgg
    30241 aggagaatat gaaaagaaaa gttcaagtaa aaaatattac tattggagaa ggtagaccta
    30301 aaatttgtgt accaattatt gggaaaaata aaaaagatat tataaaagag gctaaagagt
    30361 taaaagatgc atgtttggat attatagagt ggcgagttga tttttttgag aatgtagaaa
    30421 atattaaaga agttaaggaa gttctctatg aattaagaag ttatatacat gatatccctt
    30481 tattattcac atttagaagt gtagtagaag ggggagaaaa attaatatca agagattatt
    30541 atactacttt gaataaagaa atttctaata caggtttagt agatttaata gatgtagagt
    30601 tatttatggg agatgaggtc atagatgaag tagttaattt tgctcataaa aaagaagtga
    30661 aagtaattat atctaatcat gattttaata aaactccaaa aaaagaagag attgtatctc
    30721 gtttatgtag aatgcaggaa ttgggcgcag atttacccaa aatagctgtt atgccgcaaa
    30781 atgaaaaaga tgtgttagtg ctacttgaag ctacaaatga aatgtttaaa atttatgcag
    30841 atagaccaat aataacaatg tcaatgtcag gaatgggtgt tataagtaga ttgtgtggtg
    30901 aaatatttgg ttctgcattg acttttggag ctgcaaaaag tgtttcagca ccagggcaaa
    30961 tatcatttaa agagttaaat tcagtactta atctattaca taagagtatt aattaaatta
    31021 attatataga aatattagac ggtatttttg aagatataaa ttaaatataa aaaacttttc
    31081 agatagtaaa atttaaattg ggcaattata tctgaaaagc aactatttag tgtgtatttt
    31141 gaaagtgata tagaaaatct tataaatcaa ctatggcata tttaaaatat gccattaaaa
    31201 cctactagac attagattat agatggtata ctagcatttc tattatttat agatagtaag
    31261 ttttcataat aactgtttta tctaaagtag aagatatatt tgtattatgt atatttgtca
    31321 ttattttttt gtaattatgt atattaatgg ttatatatgt aatataatat tatcactcta
    31381 ttttttgtat attgtacatt acaacattta tatctatcat catcaattac agtagaatgt
    31441 atgggatact tattttcact taaccaatat ttttgcatat tctttgtcca agactttgga
    31501 aacttcaata ctttcttgtt tattataaca tcctcatctt caaaaatatt aacttctctt
    31561 tctattttta tttttctgtt gtatatctta ttgatagatt ctttgtcgag ttttatgtct
    31621 ctatacatat cagggcaata gcaacaaaca taatttcttt tttttcgacg tttaaatttc
    31681 acaactttct ctatgctaat ttctaatttt tttgtaccat cttttataaa tttaatatct
    31741 tctatgttct cgcttgaaaa aatttctgtc aatcttaaag tatctacagt ttctctaatt
    31801 atttgctttt tataagaaga gaatccatat ccaaaagaaa ggtttaattt attagggatg
    31861 tagccatttt tatatttaaa catcttaatt ttttccaatt cagcattatc tttaaatttc
    31921 aacttttcat acctaaaagt tactttgcta aaaagagtat attctacatc aatatattct
    31981 tttgcaatct taaatttatc gctaccttca atcacaatca tagcctatct ccaatcgttt
    32041 tatattaaaa taaggccata gaacatggtc taatagtact cattagcact ataagacaat
    32101 gttaacacaa aaagacaaaa aaaggttatt tatttcaaat aacctttttt tttatataaa
    32161 atataaagaa ttatatttta ttctttttta tgatgtctat aatctgtgat atcagattta
    32221 gttctcttga atttaagtct tttaactctt catttatatc attttctaaa tatgtttttc
    32281 cagtggaagt aatatctttt ataagaacat ctgcagaaat atttaatata tttacaaatt
    32341 ttatgaatgt tttaagactt ggattctttt taccactttc gatttgagtt atataccaag
    32401 gcgatactcc aaccatattt gcaaattctt ttgaagttaa atttgctttt ttccgttctt
    32461 ctttaagtct tttacctata taattcatta ttgttactat ttccctcact tatatttctt
    32521 tgtatttaat gatgcacttt attaactcta gcattgcaat ttgttctttt tcagttaatt
    32581 tattaatcat ttcataacat tctaaaggta cagagttatc aacgccttct gttgtaataa
    32641 tatttgcaaa taacaattca agtggtatgt ctaaagcagt agcaattttc attataatat
    32701 tgatagatgt atttgtctca gctctttcaa tctgaccaat atatgttgga tgtaaacctg
    32761 ccttttctgc tagaaactct tgactatatc ccaattttgt tctatagact tttattctat
    32821 ctcctattat ttttcctata tttgccaatt attatccctc cactttagat tatattcata
    32881 gtttaagttg ttttatatag actatttata cttttttagt ctaaatatag actatatatg
    32941 tttttatact gaaataagtg ctatttattt ttgtatagtc tgtatctaca ataaacaaat
    33001 atggataaat catattttta attagagaaa tattttcata atttcatagc catactacaa
    33061 taataaaacg aattaataat atgttaatta tagcattttt tattgt
//
LOCUS       DAYAKB010000040        32584 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.040, whole genome shotgun sequence.
ACCESSION   DAYAKB010000040 DAYAKB010000000
VERSION     DAYAKB010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.040"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     regulatory      320..396
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            661..1917
                     /locus_tag="ACGI3L_002226"
     CDS             661..1917
                     /locus_tag="ACGI3L_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFG9197929.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNACSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            1980..3173
                     /locus_tag="ACGI3L_002227"
     CDS             1980..3173
                     /locus_tag="ACGI3L_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFG9197930.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            3374..3754
                     /locus_tag="ACGI3L_002228"
     CDS             3374..3754
                     /locus_tag="ACGI3L_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9197931.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            4662..5216
                     /gene="tcdR"
                     /locus_tag="ACGI3L_002229"
     CDS             4662..5216
                     /gene="tcdR"
                     /locus_tag="ACGI3L_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HFG9197932.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSIFEEDICFFGYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            5534..12634
                     /gene="tcdB"
                     /locus_tag="ACGI3L_002230"
                     /gene_synonym="toxB"
     CDS             5534..12634
                     /gene="tcdB"
                     /locus_tag="ACGI3L_002230"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Toxigenic strains produce this toxin (TcdB) or
                     TcdA. TcdB-producing strains are tumorigenic in mice;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HFG9197933.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            12756..13256
                     /gene="tcdE"
                     /locus_tag="ACGI3L_002231"
     CDS             12756..13256
                     /gene="tcdE"
                     /locus_tag="ACGI3L_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HFG9197934.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            13365..13496
                     /locus_tag="ACGI3L_002232"
     CDS             13365..13496
                     /locus_tag="ACGI3L_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197935.1"
                     /translation="MPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKDGAWSVGKIY"
     gene            13561..13767
                     /locus_tag="ACGI3L_002233"
     CDS             13561..13767
                     /locus_tag="ACGI3L_002233"
                     /inference="COORDINATES: protein motif:HMM:NF022413.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BhlA/UviB family holin-like peptide"
                     /protein_id="HFG9197936.1"
                     /translation="MKLFKNTKIRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKT
                     LKKYKICLQITIRQSPYLIEESIN"
     gene            13984..22116
                     /gene="tcdA"
                     /locus_tag="ACGI3L_002234"
                     /gene_synonym="toxA"
     CDS             13984..22116
                     /gene="tcdA"
                     /locus_tag="ACGI3L_002234"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HFG9197937.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(22451..23149)
                     /gene="tcdC"
                     /locus_tag="ACGI3L_002235"
     CDS             complement(22451..23149)
                     /gene="tcdC"
                     /locus_tag="ACGI3L_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HFG9197938.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            23575..23820
                     /gene="cdd1"
                     /locus_tag="ACGI3L_002236"
     CDS             23575..23820
                     /gene="cdd1"
                     /locus_tag="ACGI3L_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein Cdd1"
                     /protein_id="HFG9197939.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(24038..24307)
                     /locus_tag="ACGI3L_002237"
     CDS             complement(24038..24307)
                     /locus_tag="ACGI3L_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HFG9197940.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(25185..25922)
                     /locus_tag="ACGI3L_002238"
     CDS             complement(25185..25922)
                     /locus_tag="ACGI3L_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197941.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(25934..26695)
                     /locus_tag="ACGI3L_002239"
     CDS             complement(25934..26695)
                     /locus_tag="ACGI3L_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197942.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(26695..27618)
                     /locus_tag="ACGI3L_002240"
     CDS             complement(26695..27618)
                     /locus_tag="ACGI3L_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9197943.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     TIMQRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     SIKELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            27780..28487
                     /locus_tag="ACGI3L_002241"
     CDS             27780..28487
                     /locus_tag="ACGI3L_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9197944.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            28532..29938
                     /locus_tag="ACGI3L_002242"
     CDS             28532..29938
                     /locus_tag="ACGI3L_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9197945.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            31699..32088
                     /locus_tag="ACGI3L_002243"
     CDS             31699..32088
                     /locus_tag="ACGI3L_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9197946.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT        12712 a         3547 c         5091 g        11234 t
ORIGIN      
        1 agtgaagaaa atatttaaat catgtatcat aatataagca gagtgaagaa aatatttaaa
       61 tcatgtatca taatataagc agagtgaaga aaaatattta aataatatat cataatgtgg
      121 agtgaggaaa aatatttaag ttatgtatca taatgcaaag taaagaaaat catttaaatt
      181 atatatcata aaaataatat gaaatattga acactcataa tattagaggc tttactattt
      241 taattgatag gttatattat ttataacatt aaaaatacaa tttacataaa atagacatat
      301 gaaaaataaa aaattatata ataattatgg gaatgaggtt ctcccttgga tgataatatc
      361 ctaaactgcc aatgagctga tgacttctat gatatcatag atgccaccag ctttttttgt
      421 tgtttaaatc aataaaatgg aggtgaagta cttactaaat ttttattttt taaatttgaa
      481 gaaatattta attaatagaa aaaatagtag attatatgtt aattatttta ttaagaatgg
      541 gttaagagtg tacctatatc ctatcaattt aaaaaacaat tatgatagtc attacattga
      601 ctacagttga tgtaataaaa ctttcaaaaa atcttatgat gcaaatagaa aggaattaaa
      661 atgatagaaa aatttaaaac tttaatatgg attaaaatga taataagaat taaaagcgtt
      721 tataaaacat atggtggact atttttttta ggactcatag gtataccagt tggtgcaatt
      781 ataggtctta tagacaccat atttggaacg gttcttctaa aagttacaga tattcgagaa
      841 acatatccaa tgtatctgat accattttta gcagtagtag gagttgttat tgcttattgc
      901 tattttaaat ttggaggaaa aagtagtaaa ggaatgaatc taatatttga ggtagggcat
      961 ggagaagaag aaattattcc tttaagattg gttccattta taatatcagg tacatggtta
     1021 acccatttat ttggtggtag tgcaggacga gaaggagttg ctgttcagat tggtgcaact
     1081 ttttcacatt gggtaggtaa aaggttgcct ataaaaaatg cttgtagtat ttttctagta
     1141 actggtatgg cagctggttt tgcaggatta tttgagacac caatagcagc aatactattt
     1201 gctatggagg ttttggtagc tggttcactg gagtatcaat cgctttttcc tgcgtttact
     1261 gcttctttta cagcaagttc agtatcaaaa gctttagggt tagagaaatt ttcttttgca
     1321 ctttcttcta aagttgtatt tgacttgtca atattttgga agcttattgt tttaggaatt
     1381 atttttggaa tggttggtgg agcatttgca tggtgtctga aattgtcaaa aagaaaaata
     1441 ggtaatagat taaaaaatcc tatgataaga attgctatta ttggagtatg tcttagtgta
     1501 ttattccttt tattttataa aggaagatat tcaggtttag ggacaaattt aattcaaaat
     1561 agtttctatg gtggagaaat ttattcattt gattggctgt taaagtttat acttacaata
     1621 ctgactttgt cagcaggttt tcaaggagga gaggttacac ctttgttttc cattggagct
     1681 agtcttggtg tattgttagc aggatttttt aatttgccaa ttgaattagt tgcagcgctt
     1741 ggctatgcta gtgtctttgg tagtgctaca aatacttttt ttgcacctgt atttataggg
     1801 gcagaagttt ttggatacag ctatttacct tatttctttg tagtatgcgc tatttcatat
     1861 atatttaata tggataaatc tatttattca ctacaaaaaa tttcaacaaa acaataaata
     1921 aaacaacata atgtatgatt agaagagaaa gaatattaga gaaaggatag ggtaggaata
     1981 tgttgacaag tttagctttg atttttttat taggaatggc ctcgggaggt atttttaaga
     2041 ggataaagtt acctaactta ttgggaatgt tacttacagg aattatatta ggtccatatg
     2101 ttttaaattt gattgataat tcaatactag atatttcttc tgaccttaga aagattgcat
     2161 tgattattat attaacaagg gctggattat ctttagatat aaacgatttg aagaaagtgg
     2221 gaagacctgc tgtacttatg tgctttattc cagctacttt tgaaattatc ggaatgatag
     2281 ttttagcacc aaaattacta ggcgtttcta tattggaagc agcagtcatg ggtgcagtag
     2341 taggagcagt ttctcccgca attattgtac ctaaaatgct taaattaatg gaagaaggtt
     2401 atggtacaga aaaaagtatt ccacagatgc ttttagcagg aacttctata gacgatattt
     2461 tcgtaattgt gatgtttaca gtattcacag gattggcaca aggaaatagt atatcagcta
     2521 ttagtttttt acaaattcca gtatcaatta tattaggtgt aatagttgga gcagtgattg
     2581 gaatctgttt agcagtattt tttaagaagg ttcatatgag agattctgct aaaggggtgt
     2641 tgcttttaag tatctcattt ttaatgataa gtttagagac tgctttagag ggtattgtgc
     2701 cattttctgg attattagca gttatgagta ttgggatttt ccttcagata aaatatcgtg
     2761 tagttgcaag aagattgtcc ataaagtatt caaaactatg ggttggcgct gaaattctct
     2821 tgtttgtttt ggtaggggca acagtagata taagttatgc atttaaagca ggaattggag
     2881 ctgtaatttt aatatttgga gttcttttat tccgtatggt aggagtattc ttctgcctta
     2941 ttaagacaaa tttgacaata aaggaaaggt tgttctgtat gattggctat attccaaagg
     3001 ctacagtaca ggcagcaata ggaggtgtac cacttgcaat ggggatggca tctggacaac
     3061 ttattttgac gttagcagtt ctagctatac ttataactgc acctcttgga gcttttggaa
     3121 ttgatgtaac ttataaaaaa ttattaactt ctgtaaaagg cgagagtaag taaaaataaa
     3181 gattatttta actggtaagt tatattttgg aaaaggatta tactattgaa tacaatataa
     3241 aaaaatcatt tgggagatta agaaggtaga agttaagaac agattttaag gtatgttatg
     3301 attattagaa ttgattttgt gaaattatta ttgtaatatt taattatata gataaagaag
     3361 cggagtgata actatgtgtt taaaaaaatt atcaaaatta gagttagtta ttatgaaatt
     3421 tatttggaat ttagatataa aaaccaattc atatgagatt attgattata tgaaagaaga
     3481 acataattta ccagaaaaag tagctttaaa aactttatca aaactatcaa agaaaagatt
     3541 cttatatgtt caagaaacag gcaagtgtat gtattataca gttgcaataa aagaaaaggc
     3601 atatttagag tttatatcaa gaaatgtgca aaatcttttg aagaataatt ttataaggaa
     3661 tttattagta tcatttcacg aagaggagct aacagaggaa aagataaagt cgttagaaaa
     3721 ctgggtagta aattgggaag aagcttatgt ataaatgtta ttatttttat tacaatttag
     3781 ataattttgg ttttgtaagc tctgcaacta tttttagatg gttgcagagt ttatttttat
     3841 tttttattcc cttaagcaat acttaaaagt aaacgcattt atatttacta acttcaatta
     3901 cttctaatac ttaaattact ttttaaaaat attttgatat gtcatctcta tagtaatcta
     3961 gaacttgttt ctattcttta tataaagttt ttatgaatga tatatataat attcgttcat
     4021 ttgattaaaa ataacaaaat attaaataat tctactctga tagtttgtta aaaaaataat
     4081 aaaaaatatt aataaacaaa aaaaaaatta tcttaagaga ggagaatgtt ctaaaatata
     4141 aaaaggtttc tagatttcat aaaagatact attttagtct tgaaaatatt tagtttgaaa
     4201 agattttaat ttaatgattg attaagttaa aaatgtgtat gtaataaatt ttattttatt
     4261 tattgactaa attataaagt ttacataatt atttaataat tatgtaattg ttacttgaaa
     4321 attgatctat tttaaaatct agttataact tcaaaaaaga ctgaaaatta agaaaaaaga
     4381 aatataaata taaaaatatg tcatatagat tttttttatt ttactttaat aaaatgattt
     4441 gtttttacaa tactttatta atataaagtt tattgctaaa atactttatt tattagaaaa
     4501 agattactaa ttaattatta aaattaatgt attcataatg tatattttca tataaaattt
     4561 aatttatttg ccgattatat aattataatg actgatttaa ttccaatgtt gtcaaaattt
     4621 tcaaataaat catcattata aatataagag aggatgattt tatgcaaaag tctttttatg
     4681 aattaattgt tttagcaaga aataactcag tagatgattt gcaagaaatt ttatttatgt
     4741 ttaagccatt agtaaaaaaa cttagtagag ttttacatta tgaagaggga gaaacagatt
     4801 taataatatt ttttattgaa ttaataaaaa atattaaatt aagtagcttt tcagaaaaaa
     4861 gcgatgctat tatagtcaaa tatattcata aatcattact gaataagact tttgagttgt
     4921 ctagaagata ttctaaaatg aagtttaatt ttgtagaatt tgatgaaaat atcttaaata
     4981 tgaaaaataa ttatcaaagt aagtctattt ttgaggaaga tatttgtttt ttcggatata
     5041 ttttgaaaga attatctggt attcaaagaa aagttatttt ttataaatat ttaaaaggat
     5101 attctgatag agaaatatca gtgaaattaa aaatatctag acaagctgtt aataaggcta
     5161 aaaatagagc atttaaaaaa ataaaaaaag actatgaaaa ttattttaac ttgtaattaa
     5221 tgagtttaaa gaaatattta caatagaaat caaattttat aattaacttt attgtaaaat
     5281 taataactta atctaagaat atcttaattt ttatatttta tatagaacaa tgtttacata
     5341 tttatttcag acaacgtctt tattcaatcg aagagcaaat taatcaactg agtgtcttaa
     5401 atttaaaatg ttaggaagtg aatgtatatg aaaacctaag tagatattag tatattttat
     5461 aaatagaaag gaggatatat aaaagagttt tagcatttag atgtaaaaat attatagtaa
     5521 aggagaaaat tttatgagtt tagttaatag aaaacagtta gaaaaaatgg caaatgtaag
     5581 atttcgtact caagaagatg aatatgttgc aatattggat gctttagaag aatatcataa
     5641 tatgtcagag aatactgtag tcgaaaaata tttaaaatta aaagatataa atagtttaac
     5701 agatatttat atagatacat ataaaaaatc tggtagaaat aaagccttaa aaaaatttaa
     5761 ggaatatcta gttacagaag tattagagct aaagaataat aatttaactc cagttgagaa
     5821 aaatttacat tttgtttgga ttggaggtca aataaatgac actgctatta attatataaa
     5881 tcaatggaaa gatgtaaata gtgattataa tgttaatgtt ttttatgata gtaatgcatt
     5941 tttgataaac acattgaaaa aaactgtagt agaatcagca ataaatgata cacttgaatc
     6001 atttagagaa aacttaaatg accctagatt tgactataat aaattcttca gaaaacgtat
     6061 ggaaataatt tatgataaac agaaaaattt cataaactac tataaagctc aaagagaaga
     6121 aaatcctgaa cttataattg atgatattgt aaagacatat ctttcaaatg agtattcaaa
     6181 ggagatagat gaacttaata cctatattga agaatcctta aataaaatta cacagaatag
     6241 tggaaatgat gttagaaact ttgaagaatt taaaaatgga gagtcattca acttatatga
     6301 acaagagttg gtagaaaggt ggaatttagc tgctgcttct gacatattaa gaatatctgc
     6361 attaaaagaa attggtggta tgtatttaga tgttgatatg ttaccaggaa tacaaccaga
     6421 cttatttgag tctatagaga aacctagttc agtaacagtg gatttttggg aaatgacaaa
     6481 gttagaagct ataatgaaat acaaagaata tataccagaa tatacctcag aacattttga
     6541 catgttagac gaagaagttc aaagtagttt tgaatctgtt ctagcttcta agtcagataa
     6601 atcagaaata ttctcatcac ttggtgatat ggaggcatca ccactagaag ttaaaattgc
     6661 atttaatagt aagggtatta taaatcaagg gctaatttct gtgaaagact catattgtag
     6721 caatttaata gtaaaacaaa tcgagaatag atataaaata ttgaataata gtttaaatcc
     6781 agctattagc gaggataatg attttaatac tacaacgaat acctttattg atagtataat
     6841 ggctgaagct aatgcagata atggtagatt tatgatggaa ctaggaaagt atttaagagt
     6901 tggtttcttc ccagatgtta aaactactat taacttaagt ggccctgaag catatgcggc
     6961 agcttatcaa gatttattaa tgtttaaaga aggcagtatg aatatccatt tgatagaagc
     7021 tgatttaaga aactttgaaa tctctaaaac taatatttct caatcaactg aacaagaaat
     7081 ggctagctta tggtcatttg acgatgcaag agctaaagct caatttgaag aatataaaag
     7141 gaattatttt gaaggttctc ttggtgaaga tgataatctt gatttttctc aaaatatagt
     7201 agttgacaag gagtatcttt tagaaaaaat atcttcatta gcaagaagtt cagagagagg
     7261 atatatacac tatattgttc agttacaagg agataaaatt agttatgaag cagcatgtaa
     7321 cttatttgca aagactcctt atgatagtgt actatttcag aaaaatatag aagattcaga
     7381 aattgcatat tattataatc ctggagatgg tgaaatacaa gaaatagaca agtataaaat
     7441 tccaagtata atttctgata gacctaagat taaattaaca tttattggtc atggtaaaga
     7501 tgaatttaat actgatatat ttgcaggttt tgatgtagat tcattatcca cagaaataga
     7561 agcagcaata gatttagcta aagaggatat ttctcctaag tcaatagaaa taaatttatt
     7621 aggatgtaat atgtttagct actctatcaa cgtagaggag acttatcctg gaaaattatt
     7681 acttaaagtt aaagataaaa tatcagaatt aatgccatct ataagtcaag actctattat
     7741 agtaagtgca aatcaatatg aagttagaat aaatagtgaa ggaagaagag aattattgga
     7801 tcattctggt gaatggataa ataaagaaga aagtattata aaggatattt catcaaaaga
     7861 atatatatca tttaatccta aagaaaataa aattacagta aaatctaaaa atttacctga
     7921 gctatctaca ttattacaag aaattagaaa taattctaat tcaagtgata ttgaactaga
     7981 agaaaaagta atgttaacag aatgtgagat aaatgttatt tcaaatatag atacgcaaat
     8041 tgttgaggaa aggattgaag aagctaagaa tttaacttct gactctatta attatataaa
     8101 agatgaattt aaactaatag aatctatttc tgatgcacta tgtgacttaa aacaacagaa
     8161 tgaattagaa gattctcatt ttatatcttt tgaggacata tcagagactg atgagggatt
     8221 tagtataaga tttattaata aagaaactgg agaatctata tttgtagaaa ctgaaaaaac
     8281 aatattctct gaatatgcta atcatataac tgaagagatt tctaagataa aaggtactat
     8341 atttgatact gtaaatggta agttagtaaa aaaagtaaat ttagatacta cacacgaagt
     8401 aaatacttta aatgctgcat tttttataca atcattaata gaatataata gttctaaaga
     8461 atctcttagt aatttaagtg tagcaatgaa agtccaagtt tacgctcaat tatttagtac
     8521 tggtttaaat actattacag atgcagccaa agttgttgaa ttagtatcaa ctgcattaga
     8581 tgaaactata gacttacttc ctacattatc tgaaggatta cctataattg caactattat
     8641 agatggtgta agtttaggtg cagcaatcaa agagctaagt gaaacgagtg acccattatt
     8701 aagacaagaa atagaagcta agataggtat aatggcagta aatttaacaa cagctacaac
     8761 tgcaatcatt acttcatctt tgggggtagc tagtggattt agtatacttt tagttccttt
     8821 agcaggaatt tcagcaggta taccaagctt agtaaacaat gaacttgtac ttcgagataa
     8881 ggcaacaaag gttgtagatt attttaaaca tgtttcatta gttgaaactg aaggagtatt
     8941 tactttatta gatgataaaa taatgatgcc acaagatgat ttagtgatat cagaaataga
     9001 ttttaataat aattcaatag ttttaggtaa atgtgaaatc tggagaatgg aaggtggttc
     9061 aggtcatact gtaactgatg atatagatca cttcttttca gcaccatcaa taacatatag
     9121 agagccacac ttatctatat atgacgtatt ggaagtacaa aaagaagaac ttgatttgtc
     9181 aaaagattta atggtattac ctaatgctcc aaatagagta tttgcttggg aaacaggatg
     9241 gacaccaggt ttaagaagct tagaaaatga tggcacaaaa ctgttagacc gtataagaga
     9301 taactatgaa ggtgagtttt attggagata ttttgctttt atagctgatg ctttaataac
     9361 aacattaaaa ccaagatatg aagatactaa tataagaata aatttagata gtaatactag
     9421 aagttttata gttccaataa taactacaga atatataaga gaaaaattat catattcttt
     9481 ctatggttca ggaggaactt atgcattgtc tctttctcaa tataatatgg gtataaatat
     9541 agaattaagt gaaagtgatg tttggattat agatgttgat aatgttgtga gagatgtaac
     9601 tatagaatct gataaaatta aaaaaggtga tttaatagaa ggtattttat ctacactaag
     9661 tattgaagag aataaaatta tcttaaatag ccatgagatt aatttttctg gtgaggtaaa
     9721 tggaagtaat ggatttgttt ctttaacatt ttcaatttta gaaggaataa atgcaattat
     9781 agaagttgat ttattatcta aatcatataa attacttatt tctggcgaat taaaaatatt
     9841 gatgttaaat tcaaatcata ttcaacagaa aatagattat ataggattca atagcgaatt
     9901 acagaaaaat ataccatata gctttgtaga tagtgaagga aaagagaatg gttttattaa
     9961 tggttcaaca aaagaaggtt tatttgtatc tgaattacct gatgtagttc ttataagtaa
    10021 ggtttatatg gatgatagta agccttcatt tggatattat agtaataatt tgaaagatgt
    10081 caaagttata actaaagata atgttaatat attaacaggt tattatctta aggatgatat
    10141 aaaaatctct ctttctttga ctctacaaga tgaaaaaact ataaagttaa atagtgtgca
    10201 tttagatgaa agtggagtag ctgagatttt gaagttcatg aatagaaaag gtaatacaaa
    10261 tacttcagat tctttaatga gctttttaga aagtatgaat ataaaaagta ttttcgttaa
    10321 tttcttacaa tctaatatta agtttatatt agatgctaat tttataataa gtggtactac
    10381 ttctattggc caatttgagt ttatttgtga tgaaaatgat aatatacaac catatttcat
    10441 taagtttaat acactagaaa ctaattatac tttatatgta ggaaatagac aaaatatgat
    10501 agtggaacca aattatgatt tagatgattc tggagatata tcttcaactg ttatcaattt
    10561 ctctcaaaag tatctttatg gaatagacag ttgtgttaat aaagttgtaa tttcaccaaa
    10621 tatttataca gatgaaataa atataacgcc tgtatatgaa acaaataata cttatccaga
    10681 agttattgta ttagatgcaa attatataaa tgaaaaaata aatgttaata tcaatgatct
    10741 atctatacga tatgtatgga gtaatgatgg taatgatttt attcttatgt caactagtga
    10801 agaaaataag gtgtcacaag ttaaaataag attcgttaat gtttttaaag ataagacttt
    10861 ggcaaataag ctatctttta actttagtga taaacaagat gtacctgtaa gtgaaataat
    10921 cttatcattt acaccttcat attatgagga tggattgatt ggctatgatt tgggtctagt
    10981 ttctttatat aatgagaaat tttatattaa taactttgga atgatggtat ctggattaat
    11041 atatattaat gattcattat attattttaa accaccagta aataatttga taactggatt
    11101 tgtgactgta ggcgatgata aatactactt taatccaatt aatggtggag ctgcttcaat
    11161 tggagagaca ataattgatg acaaaaatta ttatttcaac caaagtggag tgttacaaac
    11221 aggtgtattt agtacagaag atggatttaa atattttgcc ccagctaata cacttgatga
    11281 aaacctagaa ggagaagcaa ttgattttac tggaaaatta attattgacg aaaatattta
    11341 ttattttgat gataattata gaggagctgt agaatggaaa gaattagatg gtgaaatgca
    11401 ctattttagc ccagaaacag gtaaagcttt taaaggtcta aatcaaatag gtgattataa
    11461 atactatttc aattctgatg gagttatgca aaaaggattt gttagtataa atgataataa
    11521 acactatttt gatgattctg gtgttatgaa agtaggttac actgaaatag atggcaagca
    11581 tttctacttt gctgaaaacg gagaaatgca aataggagta tttaatacag aagatggatt
    11641 taaatatttt gctcatcata atgaagattt aggaaatgaa gaaggtgaag aaatctcata
    11701 ttctggtata ttaaatttca ataataaaat ttactatttt gatgattcat ttacagctgt
    11761 agttggatgg aaagatttag aggatggttc aaagtattat tttgatgaag atacagcaga
    11821 agcatatata ggtttgtcat taataaatga tggtcaatat tattttaatg atgatggaat
    11881 tatgcaagtt ggatttgtca ctataaatga taaagtcttc tacttctctg actctggaat
    11941 tatagaatct ggagtacaaa acatagatga caattatttc tatatagatg ataatggtat
    12001 agttcaaatt ggtgtatttg atacttcaga tggatataaa tattttgcac ctgctaatac
    12061 tgtaaatgat aatatttacg gacaagcagt tgaatatagt ggtttagtta gagttgggga
    12121 agatgtatat tattttggag aaacatatac aattgagact ggatggatat atgatatgga
    12181 aaatgaaagt gataaatatt atttcaatcc agaaactaaa aaagcatgca aaggtattaa
    12241 tttaattgat gatataaaat attattttga tgagaagggc ataatgagaa cgggtcttat
    12301 atcatttgaa aataataatt attactttaa tgagaatggt gaaatgcaat ttggttatat
    12361 aaatatagaa gataagatgt tctattttgg tgaagatggt gtcatgcaga ttggagtatt
    12421 taatacacca gatggattta aatactttgc acatcaaaat actttggatg agaattttga
    12481 gggagaatca ataaactata ctggttggtt agatttagat gaaaagagat attattttac
    12541 agatgaatat attgcagcaa ctggttcagt tattattgat ggtgaggagt attattttga
    12601 tcctgataca gctcaattag tgattagtga atagataaaa atatgttaaa tatatcctct
    12661 tatacttaaa tatataaaaa taaacaaaat gatacactac ataaagtgtt ctatctaata
    12721 tgaagattta ccaataaaaa ggtggactat gatgaatgca cagtagttca cctttttata
    12781 tttctaatgg taacaaaata tttttttata taaacctagg aggcgttatg aatatgacaa
    12841 tatctttttt atcagagcat atatttataa agttagtaat tttaactata tcatttgata
    12901 cattattagg atgtttaagt gcaataaaaa gtcgtaaatt taattctagt tttggaatag
    12961 atggaggaat cagaaaagta gcaatgatag catgtatatt ttttttatca gtagttgaca
    13021 ttcttacaaa gtttaacttt ttatttatgt taccacaaga ttgtatcaat tttttaagac
    13081 taaaacatct tggaatatct gaatttttct ctattttatt tattttatat gaaagtgtaa
    13141 gtatattaaa aaatatgtgc ttatgtggat taccagtacc taagagatta aaggaaaaaa
    13201 tagcaatttt actagatgca atgacagatg aaatgaatgc taaggatgaa aagtaagtaa
    13261 tggtagatat aataaagata ttaacaaata aaaagtgtta tccaaataag aatagctgaa
    13321 agttatcata attcatgaaa ctaataatga aaacgaggga gcagatgcca agagacacac
    13381 aagtattaaa tacatataat ttcgaagcaa gtgttcatta ctatatagat gacaaggtag
    13441 tatatcaaac attggttcac aaagatggtg catggtcagt tggtaaaatc tattaagcta
    13501 cattagttac agatatcaca aactataata gttaaacata gaaatatgtg taaattgtga
    13561 ttgaaattat tcaaaaacac aaaaatacgt gatgaaggac aaaatgatat agaaaataag
    13621 tatcaaacct taataaatga tttaattgat agtttaaaag ttataggaaa aatatataaa
    13681 gaaataaaaa cattaaaaaa atataagata tgtttacaaa ttactatcag acaatctcct
    13741 tatctaatag aagagtcaat taactaattg agtatcttta aattgaaatg ttaggaagtg
    13801 atttaaatat gaaaacttaa attataaaaa atcaatatta atttattttt aaaaaataga
    13861 aaggagtgta taagatttat tttcaaagtt taaaaacaag aaaatcaatt taaatttcag
    13921 aaggaataaa tgtggttata gaagtggatt tattatcaaa aataataata ctaggaggtt
    13981 tttatgtctt taatatctaa agaagagtta ataaaactcg catatagcat tagaccaaga
    14041 gaaaatgagt ataaaactat actaactaat ttagacgaat ataataagtt aactacaaac
    14101 aataatgaaa ataaatattt acaattaaaa aaactaaatg aatcaattga tgtttttatg
    14161 aataaatata aaacttcaag cagaaataga gcactctcta atctaaaaaa agatatatta
    14221 aaagaagtaa ttcttattaa aaattccaat acaagccctg tagaaaaaaa tttacatttt
    14281 gtatggatag gtggagaagt cagtgatatt gctcttgaat acataaaaca atgggctgat
    14341 attaatgcag aatataatat taaactgtgg tatgatagtg aagcattctt agtaaataca
    14401 ctaaaaaagg ctatagttga atcttctacc actgaagcat tacagctact agaggaagag
    14461 attcaaaatc ctcaatttga taatatgaaa ttttacaaaa aaaggatgga atttatatat
    14521 gatagacaaa aaaggtttat aaattattat aaatctcaaa tcaataaacc tacagtacct
    14581 acaatagatg atattataaa gtctcatcta gtatctgaat ataatagaga tgaaactgta
    14641 ttagaatcat atagaacaaa ttctttgaga aaaataaata gtaatcatgg gatagatatc
    14701 agggctaata gtttgtttac agaacaagag ttattaaata tttatagtca ggagttgtta
    14761 aatcgtggaa atttagctgc agcatctgac atagtaagat tattagccct aaaaaatttt
    14821 ggcggagtat atttagatgt tgatatgctt ccaggtattc actctgattt atttaaaaca
    14881 atatctagac ctagctctat tggactagac cgttgggaaa tgataaaatt agaggctatt
    14941 atgaagtata aaaaatatat aaataattat acatcagaaa actttgataa acttgatcaa
    15001 caattaaaag ataattttaa actcattata gaaagtaaaa gtgaaaaatc tgagatattt
    15061 tctaaattag aaaatttaaa tgtatctgat cttgaaatta aaatagcttt cgctttaggc
    15121 agtgttataa atcaagcctt gatatcaaaa caaggttcat atcttactaa cctagtaata
    15181 gaacaagtaa aaaatagata tcaattttta aaccaacacc ttaacccagc catagagtct
    15241 gataataact tcacagatac tactaaaatt tttcatgatt cattatttaa ttcagctacc
    15301 gcagaaaact ctatgttttt aacaaaaata gcaccatact tacaagtagg ttttatgcca
    15361 gaagctcgct ccacaataag tttaagtggt ccaggagctt atgcgtcagc ttactatgat
    15421 ttcataaatt tacaagaaaa tactatagaa aaaactttaa aagcatcaga tttaatagaa
    15481 tttaaattcc cagaaaataa tctatctcaa ttgacagaac aagaaataaa tagtctatgg
    15541 agctttgatc aagcaagtgc aaaatatcaa tttgagaaat atgtaagaga ttatactggt
    15601 ggatctcttt ctgaagacaa tggggtagac tttaataaaa atactgccct cgacaaaaac
    15661 tatttattaa ataataaaat tccatcaaac aatgtagaag aagctggaag taaaaattat
    15721 gttcattata tcatacagtt acaaggagat gatataagtt atgaagcaac atgcaattta
    15781 ttttctaaaa atcctaaaaa tagtattatt atacaacgaa atatgaatga aagtgcaaaa
    15841 agctactttt taagtgatga tggagaatct attttagaat taaataaata taggatacct
    15901 gaaagattaa aaaataagga aaaagtaaaa gtaaccttta ttggacatgg taaagatgaa
    15961 ttcaacacaa gcgaatttgc tagattaagt gtagattcac tttccaatga gataagttca
    16021 tttttagata ccataaaatt agatatatca cctaaaaatg tagaagtaaa cttacttgga
    16081 tgtaatatgt ttagttatga ttttaatgtt gaagaaactt atcctgggaa gttgctatta
    16141 agtattatgg acaaaattac ttccacttta cctgatgtaa ataaaaattc tattactata
    16201 ggagcaaatc aatatgaagt aagaattaat agtgagggaa gaaaagaact tctggctcac
    16261 tcaggtaaat ggataaataa agaagaagct attatgagcg atttatctag taaagaatac
    16321 attttttttg attctataga taataagcta aaagcaaagt ccaagaatat tccaggatta
    16381 gcatcaatat cagaagatat aaaaacatta ttacttgatg caagtgttag tcctgataca
    16441 aaatttattt taaataatct taagcttaat attgaatctt ctattggtga ttacatttat
    16501 tatgaaaaat tagagcctgt taaaaatata attcacaatt ctatagatga tttaatagat
    16561 gagttcaatc tacttgaaaa tgtatctgat gaattatatg aattaaaaaa attaaataat
    16621 ctagatgaga agtatttaat atcttttgaa gatatctcaa aaaataattc aacttactct
    16681 gtaagattta ttaacaaaag taatggtgag tcagtttatg tagaaacaga aaaagaaatt
    16741 ttttcaaaat atagcgaaca tattacaaaa gaaataagta ctataaagaa tagtataatt
    16801 acagatgtta atggtaattt attggataat atacagttag atcatacttc tcaagttaat
    16861 acattaaacg cagcattctt tattcaatca ttaatagatt atagtagcaa taaagatgta
    16921 ctgaatgatt taagtacctc agttaaggtt caactttatg ctcaactatt tagtacaggt
    16981 ttaaatacta tatatgactc tatccaatta gtaaatttaa tatcaaatgc agtaaatgat
    17041 actataaatg tactacctac aataacagag gggataccta ttgtatctac tatattagac
    17101 ggaataaact taggtgcagc aattaaggaa ttactagacg aacatgaccc attactaaaa
    17161 aaagaattag aagctaaggt gggtgtttta gcaataaata tgtcattatc tatagctgca
    17221 actgtagctt caattgttgg aataggtgct gaagttacta ttttcttatt acctatagct
    17281 ggtatatctg caggaatacc ttcattagtt aataatgaat taatattgca tgataaggca
    17341 acttcagtgg taaactattt taatcatttg tctgaatcta aaaaatatgg ccctcttaaa
    17401 acagaagatg ataaaatttt agttcctatt gatgatttag taatatcaga aatagatttt
    17461 aataataatt cgataaaact aggaacatgt aatatattag caatggaggg gggatcagga
    17521 cacacagtga ctggtaatat agatcacttt ttctcatctc catctataag ttctcatatt
    17581 ccttcattat caatttattc tgcaataggt atagaaacag aaaatctaga tttttcaaaa
    17641 aaaataatga tgttacctaa tgctccttca agagtgtttt ggtgggaaac tggagcagtt
    17701 ccaggtttaa gatcattgga aaatgacgga actagattac ttgattcaat aagagattta
    17761 tacccaggta aattttactg gagattctat gcttttttcg attatgcaat aactacatta
    17821 aaaccagttt atgaagacac taatattaaa attaaactag ataaagatac tagaaacttc
    17881 ataatgccaa ctataactac taacgaaatt agaaacaaat tatcttattc atttgatgga
    17941 gcaggaggaa cttactcttt attattatct tcatatccaa tatcaacgaa tataaattta
    18001 tctaaagatg atttatggat atttaatatt gataatgaag taagagaaat atctatagaa
    18061 aatggtacta ttaaaaaagg aaagttaata aaagatgttt taagtaaaat tgatataaat
    18121 aaaaataaac ttattatagg caatcaaaca atagattttt caggcgatat agataataaa
    18181 gatagatata tattcttgac ttgtgagtta gatgataaaa ttagtttaat aatagaaata
    18241 aatcttgttg caaaatctta tagtttgtta ttgtctgggg ataaaaatta tttgatatcc
    18301 aatttatcta atactattga gaaaatcaat actttaggcc tagatagtaa aaatatagcg
    18361 tacaattaca ctgatgaatc taataataaa tattttggag ctatatctaa aacaagtcaa
    18421 aaaagcataa tacattataa aaaagacagt aaaaatatat tagaatttta taatgacagt
    18481 acattagaat ttaacagtaa agattttatt gctgaagata taaatgtatt tatgaaagat
    18541 gatattaata ctataacagg aaaatactat gttgataata atactgataa aagtatagat
    18601 ttctctattt ctttagttag taaaaatcaa gtaaaagtaa atggattata tttaaatgaa
    18661 tccgtatact catcttacct tgattttgtg aaaaattcag atggacacca taatacttct
    18721 aattttatga atttattttt ggacaatata agtttctgga aattgtttgg gtttgaaaat
    18781 ataaattttg taatcgataa atactttacc cttgttggta aaactaatct tggatatgta
    18841 gaatttattt gtgacaataa taaaaatata gatatatatt ttggtgaatg gaaaacatcg
    18901 tcatctaaaa gcactatatt tagcggaaat ggtagaaatg ttgtagtaga gcctatatat
    18961 aatcctgata cgggtgaaga tatatctact tcactagatt tttcctatga acctctctat
    19021 ggaatagata gatatatcaa taaagtattg atagcacctg atttatatac aagtttaata
    19081 aatattaata ccaattatta ttcaaatgag tactaccctg agattatagt tcttaaccca
    19141 aatacattcc acaaaaaagt aaatataaat ttagatagtt cttcttttga gtataaatgg
    19201 tctacagaag gaagtgactt tattttagtt agatacttag aagaaagtaa taaaaaaata
    19261 ttacaaaaaa taagaatcaa aggtatctta tctaatactc aatcatttaa taaaatgagt
    19321 atagatttta aagatattaa aaaactatca ttaggatata taatgagtaa ttttaaatca
    19381 tttaattctg aaaatgaatt agatagagat catttaggat ttaaaataat agataataaa
    19441 acttattact atgatgaaga tagtaaatta gttaaaggat taatcaatat aaataattca
    19501 ttattctatt ttgatcctat agaatttaac ttagtaactg gatggcaaac tatcaatggt
    19561 aaaaaatatt attttgatat aaatactgga gcagctttaa ctagttataa aattattaat
    19621 ggtaaacact tttattttaa taatgatggt gtgatgcagt tgggagtatt taaaggacct
    19681 gatggatttg aatattttgc acctgccaat actcaaaata ataacataga aggtcaggct
    19741 atagtttatc aaagtaaatt cttaactttg aatggcaaaa aatattattt tgataatgac
    19801 tcaaaagcag tcactggatg gagaattatt aacaatgaga aatattactt taatcctaat
    19861 aatgctattg ctgcagtcgg attgcaagta attgacaata ataagtatta tttcaatcct
    19921 gacactgcta tcatctcaaa aggttggcag actgttaatg gtagtagata ctactttgat
    19981 actgataccg ctattgcctt taatggttat aaaactattg atggtaaaca cttttatttt
    20041 gatagtgatt gtgtagtgaa aataggtgtg tttagtacct ctaatggatt tgaatatttt
    20101 gcacctgcta atacttataa taataacata gaaggtcagg ctatagttta tcaaagtaaa
    20161 ttcttaactt tgaatggtaa aaaatattac tttgataata actcaaaagc agttaccgga
    20221 tggcaaacta ttgatagtaa aaaatattac tttaatacta acactgctga agcagctact
    20281 ggatggcaaa ctattgatgg taaaaaatat tactttaata ctaacactgc tgaagcagct
    20341 actggatggc aaactattga tggtaaaaaa tattacttta atactaacac tgctatagct
    20401 tcaactggtt atacaattat taatggtaaa catttttatt ttaatactga tggtattatg
    20461 cagataggag tgtttaaagg acctaatgga tttgaatatt ttgcacctgc taatacggat
    20521 gctaacaaca tagaaggtca agctatactt taccaaaatg aattcttaac tttgaatggt
    20581 aaaaaatatt actttggtag tgactcaaaa gcagttactg gatggagaat tattaacaat
    20641 aagaaatatt actttaatcc taataatgct attgctgcaa ttcatctatg cactataaat
    20701 aatgacaagt attactttag ttatgatgga attcttcaaa atggatatat tactattgaa
    20761 agaaataatt tctattttga tgctaataat gaatctaaaa tggtaacagg agtatttaaa
    20821 ggacctaatg gatttgagta ttttgcacct gctaatactc acaataataa catagaaggt
    20881 caggctatag tttaccagaa caaattctta actttgaatg gcaaaaaata ttattttgat
    20941 aatgactcaa aagcagttac tggatggcaa accattgatg gtaaaaaata ttactttaat
    21001 cttaacactg ctgaagcagc tactggatgg caaactattg atggtaaaaa atattacttt
    21061 aatcttaaca ctgctgaagc agctactgga tggcaaacta ttgatggtaa aaaatattac
    21121 tttaatacta acactttcat agcctcaact ggttatacaa gtattaatgg taaacatttt
    21181 tattttaata ctgatggtat tatgcagata ggagtgttta aaggacctaa tggatttgaa
    21241 tactttgcac ctgctaatac tcataataat aacatagaag gtcaagctat actttaccaa
    21301 aataaattct taactttgaa tggtaaaaaa tattactttg gtagtgactc aaaagcagtt
    21361 accggattgc gaactattga tggtaaaaaa tattacttta atactaacac tgctgttgca
    21421 gttactggat ggcaaactat taatggtaaa aaatactact ttaatactaa cacttctata
    21481 gcttcaactg gttatacaat tattagtggt aaacattttt attttaatac tgatggtatt
    21541 atgcagatag gagtgtttaa aggacctgat ggatttgaat actttgcacc tgctaataca
    21601 gatgctaaca atatagaagg tcaagctata cgttatcaaa atagattcct atatttacat
    21661 gacaatatat attattttgg taataattca aaagcggcta ctggttgggt aactattgat
    21721 ggtaatagat attacttcga gcctaataca gctatgggtg cgaatggtta taaaactatt
    21781 gataataaaa atttttactt tagaaatggt ttacctcaga taggagtgtt taaagggtct
    21841 aatggatttg aatactttgc acctgctaat acggatgcta acaatataga aggtcaagct
    21901 atacgttatc aaaatagatt cctacattta cttggaaaaa tatattactt tggtaataat
    21961 tcaaaagcag ttactggatg gcaaactatt aatggtaaag tatattactt tatgcctgat
    22021 actgctatgg ctgcagctgg tggacttttc gagattgatg gtgttatata tttctttggt
    22081 gttgatggag taaaagcccc tgggatatat ggctaaaata tatgtttgat aaaaaattat
    22141 tcctgtgcta ctaagaaatt atttttatat aataaatatt gagatttaat taaaagtcat
    22201 gtgttattgt aatacatgac ttttagttaa aatttttcta tcatttaata atctattatt
    22261 cttgactatt ttataataaa attcatatat ggaaatatta atactaaata attaatagtt
    22321 gataaaaaat agataatatg ctaaaagcaa aaactaattt agagccttgt aactgtttat
    22381 ttgcaattat aaaaacatct ttaaacatat tgactataat ataaaatatt aactataata
    22441 caaaacaata ttaattaatt ttctctacag ctatccctgg tatagttata tttccaccca
    22501 tagttgattc ataagttata gttccagcac ttatacctct tatagttatg taatcatcct
    22561 ctaatactct tgaaggagtt attgattttt tataactaca tagtacaacc ttatcataat
    22621 ttccagacac agctaatctt atttgcacct catcaccatc ttcaataact tgaataacct
    22681 taccttcaaa ttttaccttt ttgtacttat aatcatcagg tgttctagct aattggtcat
    22741 aagtaatacc agtatcatat cctttcttct cctcttcttc ttttttgcgt tgttcttcag
    22801 cctttttagc ttcttcagct tttttagctt cttcagcttt acgttgattt tcagcttcaa
    22861 tagctttctt ttcgtcgtct ttcattttga accatggttc agcatcagac aatttgctat
    22921 ttaaagtttc tatttctgtt ttttgagaat ctataactga tgtttggtta gaaatgacct
    22981 cctcatggtc ttcagaacaa gctggtgagg atatattgcc aaaaaacacg cctaaaataa
    23041 atgccagtag agcaataccc tttgtgctct taaagaattt aattattttc ttagagcttc
    23101 cttttccttc attactaaat tcgttaccct catttttttt agaaaacata atacaatctc
    23161 ccttttatta gatatatttt attttaaaag ttaaaaactt aaaataacta gttgactaaa
    23221 aattatatat tcatattttc ctaaaatata tttcccctaa gcataatttt acaaaataaa
    23281 gtaagaagat tcaatatatt ttgaaaaaat aagataaaaa tgtcagatta taatataatt
    23341 ttcttgaagg tgaattttat atattaaatt aaacataaag tattttattt gtataaaact
    23401 atattatgat gtaattaagt gactcagtga tttagaggtg gtaaaatata tatatatgaa
    23461 agagcataaa taaattgata taataaaaaa ttaaatatta aatattaact ataataaaaa
    23521 aatatctggt aataggtata atataaaaag aatataccag aaagaaggtg aagtatggga
    23581 gaactacaaa aaattccagg ggtagggaaa gcaacagaaa aatctttaat catgttagga
    23641 tatacaacta ttaaatcact taaagatgca aacccagcac aaatgtatga aaaggaatgt
    23701 ttaatgcgtg gacagcacat agacagatgt cagttatatg tatacagatg tgcagtatat
    23761 tttgcatcaa ctgaaaatcc agaaccagaa aaattaaagt ggtggtattg gaaagattaa
    23821 aaaatcaaaa aagttagaca taaaaaagag ttgaatatcc gttttaaata ataaaaacta
    23881 atactcaact cttttttagt cgtaaatttt atgtaaatct atttgtatgg ctaaatatac
    23941 ccatcaataa atgtataaat atactaatca acaaatgact aaacatacta cctaacaaag
    24001 gattaaataa attccttaac aaagcattct aaaacaatta attagaaact gtttcttcaa
    24061 gccattttct acattgctca atatttacca tagggtcaaa accttggtct tttcccttat
    24121 ttaaaagcat atcacaaggg aaagtatcac attcaccaca atgattaagt tccttacttt
    24181 cacagcaagt tttaacctta cattctccac cccaaaatgg tttttccata gttgggcaac
    24241 cagtgcaatt tacttgttct ttttttgtac aactgtcaca acagacacca catcttgatt
    24301 caaacatatt caaacatcct ttccattatt taaaaatatt ataaaatgat tttagatgaa
    24361 tacaaaagtg caaatagttg attttaggtc atctaaatgt taaacataaa attattagta
    24421 ctggtaaatt tataaaaact attccaaaaa tctttttgaa tatttcaaaa cacaataaat
    24481 tacttcaaat ccccttgaat atattttaca gcattataga ttgctttaaa tctctttgaa
    24541 tattctacaa gactatagat tagtttaaat ccctttgaat atattttaca acattataga
    24601 ttgttttaaa tctctttgaa tattctacaa gactatagat tagtttaaat ccctttgaat
    24661 atttcaaaac accatagatt actttaaatc cctttgaatg ttctataaca ctataaatta
    24721 cttttaactt ttatataacc ataaagtttt tatctggcac tttaaatgga gttttatatc
    24781 aaatttgcct tccatcgaat aaccaaactt aatttaatta cacattccaa gagtcaaata
    24841 ttcattcaat atatttgata attctatgtt atagctataa ttaaatatag attattaaag
    24901 ttaaatattt atttaatata ttgaatgatt ttttacctat atttaattaa gtttcattat
    24961 ataatataaa aattgttttt gcattaagtt ttaatataat acataataat tttaaataat
    25021 aacattatta tatattttta aattttagga gtatatctat tatatagcga gtagataaaa
    25081 catataaaat tcaaataaaa gatatatatt tttaaataaa atggatatag atttcaacta
    25141 aaaagaatat aaatttcaaa cccaaaaata tctagcattt accattaaga aataacatca
    25201 ttctttctaa aatttctatt ggcaatttca gaaaatacta tagtagtaat aaatgcaaca
    25261 catattgtaa ctatagtgtc attaacattt aaagcagatt gctttataac ccccatagca
    25321 ctacctaaca tagaataagg gaaaaatata ccaacagcag gttttgctac tattaatccc
    25381 ataccaaata gagaaaggca aagactaata ccaataggag ttgcaaaact tctaatcttt
    25441 atagacatgt ataattgtat agaagctatt gaaatagaaa taatccaacc tttagcaatc
    25501 caaccagtca attctttagg tacactacca gaaaaaccaa acatatttcc tgcaactata
    25561 taaaagataa caaagaaaac ttgtgtaata gctgtaagta ttgaaactac tgtaagttta
    25621 gataaaaaga tattttttaa attaactggc agtgtcatta cattattcca attatgattc
    25681 atatgttcaa gcctacaaat atatgcacaa aagattgcga ttaagatagg aaagaaaaat
    25741 tccccataaa aaagactaac ttgagtccat aagctgtacc attctttttt gagtatgcct
    25801 tgatttagat aaaaattacc agaaccaatc aacacactta taagtggcaa agctaataat
    25861 acataccata taaaagaatt ttttaacttt agaatttctc ccaaaactga cttccttaac
    25921 atttaaatcc ctcctatact tcttttttta ataaatgatt tcttccaata taataaatta
    25981 gcattccaat taagaaaact aaaatcgtaa tagaaaaatt catatcaatt ctatagacag
    26041 atgaacctaa aacattatca taagcataac ttaaaggtga taactctagg taataagacc
    26101 atataaacaa tctacgaata ccttgataaa acaaacctga tgtcaaacct ataaaactac
    26161 caatcatgcc aaatgtaatt gcaatcattt gatttggaat tacagttgca atccataggt
    26221 gtagtgcaat gatagcaata cttacaagaa ttgttcctaa tgtgtatttt aaaagtaaag
    26281 atacagaaat tgactcaata acccctctaa aatgtccaaa caacacaata gataacactt
    26341 gcatcaatac aggtatagat accaaaatag cagaacataa aaatttagat aaataaatac
    26401 tatttaaaga tgtcacagaa gattttaaaa gcttccatgt atctccttta tgttctatat
    26461 cgcttatacg tgatgtaatt attgatatta agataggaaa gaatagacca tttaaacttg
    26521 caaaactcat aagcatatag gaatattcaa atccacctaa catatctgga ttacgtgtaa
    26581 tagctctatt tgaatttacg atacaccaca ttatttcaac agctgcaaat aaaaaggtca
    26641 tcagaataat cttctttctt ttaagtttat aaaattctag accaaggtat ttcattataa
    26701 agtcaccgcc ttaccagtaa gttctaagaa tatatcttcc aagctttttt tatgttcttc
    26761 tattctaaat acatctatat ttgaatggac aagcatacca tttattttag cgacatctga
    26821 gtcttttaaa ttttcaatag tcaagtaccc atcttgtata agtgacatat atcctttagt
    26881 atttaatagt ttttgtgcag atacaacatt cttagttttg atagcaatct gactttgacc
    26941 tctattatga agttctttta tgctatcttg aaaaaccagt tcgccatgat ttattattcc
    27001 tattgatgtg gcaatttggt caatttcact taaaagatgg ctagagatta gaacagtcat
    27061 cccgtatttt tctggtagag attttattaa ttctctaatt tcctcaatcc ctgctgggtc
    27121 gagtccattt gtaggttcat caagtattaa taatttggga aacttcatta ttgccatagc
    27181 aatgccaaga cgttgcttca tacctaaaga atattgacta acttttttat ttttttgatt
    27241 ttctaacctt acaattttta atgcttcatt tacatttttt ttaggtaaat ctaagagtct
    27301 ttgcattatg gtcatgtttt caagccctgt aagatgacca tagtatgatg gagattctat
    27361 caaagaacct atatctttta aaattgatat tctatttttt tcatttaact ctttacctaa
    27421 aatattaata tttccttgtg tgggtttagc aagtccaaga agcattttaa gagtggtaga
    27481 ttttccagct ccattaggac ccaaaaaacc atatacagct ccttgtggaa ctcttaggtc
    27541 tatatccttt actctaaata ttttattgta ttcctttgaa agtctttgtg ttctaattat
    27601 catttccata tgtttcatcc ccttttttaa tctgtgctta ttgattcttt taacttatat
    27661 cagtataata acttggttac atttcaatta gctgaaattt accttacaat aaccttaaaa
    27721 gtctatttag gcaaagttgt gaaaatgggt atatggtata ctaaaggagg gtgatgatta
    27781 tggagtcaat aaaagataaa aaaatacttg tggttgatga ccacaaggaa ttattaaaaa
    27841 tgatagatga aatcctgaga aaagagggat ttagtagagt atttttagca tcaagttatg
    27901 aggaagctgt tagggtattt agaaatgtaa agccagattg tgcaatttta gatgttgtat
    27961 tgccagatgg agatggtttt tctattatga gaaaaattag agagacatct aaaataccag
    28021 tgatttttct ctctgcaaga ggtgaagatg aagatagatt gattggtttg ggcttagggg
    28081 ctgacgatta tatagtaaag ccatttttac caaaggaact tactttaagg cttgtgggta
    28141 tattaaatcg tgtatatgtg cctatagaag aagaggagtt gccagtattt aaactgggag
    28201 attctgttgt tgtgaattta aatagtgcat gtgttgagaa agatgggcaa gagatttctt
    28261 taacagctaa agagcattcg ttgcttttaa agttgtatga aaataaaggg agaattgtta
    28321 ctaatgattc actatgtcaa gccatttggg gagatgatat gtatggatat gaaaataccc
    28381 ttatggttca tgttagaagg gttagagaga agatagaaaa aactccatct acacctaaac
    28441 atcttattac agtaagaggt cttggatata agttgatgat taattaattt tagatattag
    28501 aataaaagaa atcaagagga gtgatttaat tttggatagt gtaaagtaca tattgaggcg
    28561 atttataggt tcaagtatct tgatttcatt actttttatt gtattaaata tagcaggttt
    28621 tcttctgttt tcatatatgt tatttgtatc taaatactct gataatttag atacaagtga
    28681 tagtagagaa ataaaatcaa acttgattat gattgaagat aatttgattt taagagatgg
    28741 aaagtttatt ttagatgatt ctagtaagga agtactacat aaaaataaag tttgggcaat
    28801 gttaattgat aacaatggag atagaatatg gggatttgat ttaccaaaag aaattccaag
    28861 tcattatact ttgacagatg tagcaaagtt ttcaaggttc tttttaaagg actatcctgt
    28921 gtatgtatgg gaacatccaa atggaatatt agtaacaggt tatccaaaag acaagtatac
    28981 taagtttaac cttacttata cggttaagga aatagaacaa tttcctatgt taataatagg
    29041 tatgtttctg gttaatgcaa tagttacttt tttaatagct ctattcatag gtttaaaaat
    29101 ggtgaaatct ataaaaccaa ttattactgg cataaagctt atgtcaaaag gagaaccagt
    29161 acttttacaa gaaaaaggaa tactaagtga tatttcaaaa tctattaata ctgtatctaa
    29221 agagttgcaa atgaaagatg aaaaacttag gaagaaagag gaagctaggt ctaactggat
    29281 tgcaggaata tctcatgata taagaactcc actttcaatg ataattggat atgctggaga
    29341 acttgaagaa agcagtagcc tttcaaatag agaacaagag caagtgtcta ttatatgcaa
    29401 tcaagggatt aaaatcagag aattagtaaa tgacctaaat ttagtgtcta aacttgaata
    29461 taatatgcaa acattgaatt gtgataagat tagagtttct gcgtttttga gagagcttat
    29521 ttctgagttt ataaataata atttggataa tgacttttac gttgaacttg atatactaaa
    29581 tgaagatatt attatagatg cagataaaaa attattaaaa agggctatta gtaatttaat
    29641 acaaaatagt ataactcata accaacaagg atgtaatata agggttacct ctaagtctga
    29701 tttagatttt tgctatataa ttgttgaaga tgatggaaaa ggtatgagtc aagaaagaat
    29761 taatagttta ttaaagagcc aaaatggact aagtgaggca tatgccaaag gtcaaaatca
    29821 tggtctaggt attttgatag tatctggcat tattaatgca catagaggta aattagatat
    29881 tacgagcatt gatagtcagg gactaaaaac aatactaaaa ttacctctaa ttaagtgata
    29941 ttttataaaa taataacaga taagaatgaa gaatgaaaat attttgaaaa taattttatt
    30001 ctttattgac aaattaactc tattagagta gaataaggat aaattctttt cttgtcaagt
    30061 tttattaaag taaagagtaa cttgtgcttt atgcgcttat ggctgagtta ctcatggtat
    30121 caaaattttc atagaaataa tattttggaa ttattgtaag gttattaaat tctttagata
    30181 attccatttt ttttattttt tagttaatat ttaattttat tattgacaaa aaaattctac
    30241 taaaatagaa ttatggtata gtgtttttta attttaagaa aaaatataat gacatcctaa
    30301 aaaagtttta attataagct gttctgtgta gttataatag cttctatgta actattgtaa
    30361 gtatatttta ttatagttat ttatttaaag tacgataaat gttttaaatt gaagtatttt
    30421 gcgccattga gttctactaa agtagagttt ttgtgtagta tttttagaaa taacatatat
    30481 atatatgtat ttatgttgaa atatatggaa aatttataat ataattaatg aaaaaattta
    30541 aactttgtaa tatataaata aaaaaactct aaaatagaag gatataatta tatagaatgt
    30601 ttcaattaaa caaggtaaaa actataatct taaaattaaa attaacatta ttcttaagaa
    30661 gcaagaaatt tagaaagtag gaagtttagt gataagtggt agtaagtaag aaatttagga
    30721 agtgggaagt ttagttataa gtggtagtaa gtaagaaatt taggaagtgg gaagtttagt
    30781 tataagtggt agtaagtaag aaatttagga agtgggaagt ttagttataa gtagtagtaa
    30841 gtaagaaatt tagtaagtgg gaagtttagt agtaataatt tatagcaagt aagaaattta
    30901 ggaagtagga agtttagtaa taatttgtag caagtaagaa acttagggag taggaagttt
    30961 agtaataatt tatagcaagt aagaaattta gggagtagga agtttagtaa taatttgtag
    31021 taagtaagaa atttagaaag taggaaattt agtaataatt tatagtaagt aagaaaatta
    31081 gggagtagga agtttagtaa taatttatag taagtaagaa atttagaaag taggaagttt
    31141 agtaataatt tatagcaagt aagaaattta gggagaggaa gtttagtaat aatttgtagc
    31201 aagtaagaaa tttagaaagt aggaagttta gtagtaattt atagtaagta agaaatttag
    31261 taagtgagaa gtttagttat aatttatagt aagtaagaaa tttagtaagt gagaagttca
    31321 gtaataagtt gtagtaaata aaaagtttag gaagtaggaa gttcagtaat aagttgtagt
    31381 aaataaaaaa tttaggaagt aggatttact gaaatacaaa tatttaaaat caaagagttt
    31441 aaaagaaagg agagctactg gacaagtatc caaaatagat agctgagtac aaaatatttc
    31501 ataaaattaa gcaatataat acaagagaat tttgacatta tttatatata tttaccgtgt
    31561 acaaatagct aaatttagga ttaagattga aaaatatctt ataagtctga gcttatataa
    31621 atccgtataa gatgtattta atcgaaaaat tttattatgg atattgcttg tctatattct
    31681 gagtagcaag gttttatcat gactataaaa aagttgccac aatcagaatt aaagataatg
    31741 aaatttatat ggaaatcaga ttccaaagta acatctagag atattgtttt aggaatggag
    31801 caaaaatatc aatggaaaca aacgacaact ttgactcttt tatctagatt agtagtaaaa
    31861 agatttctaa attctcaaaa gatagataaa tatacgcatt atgaagtttt aattaaagaa
    31921 aaggaataca taggagttga gacaagagat ttttttagaa atattcatga ttcttctata
    31981 aaaagtttat tgttgtcatt acatgaaaat attaatttga gcaaagatga tattttactt
    32041 attgaagagt ggataaaaaa tctaaaagaa gaggagaaag acgtataagc aaacgtattt
    32101 cttatagcat caatataaag tgtatgtaag tgtatttatg taatatatta gtctacttaa
    32161 gtaatatgac aaatgattat aagtggatta tgatactata atgtgaatct aaataaatta
    32221 aatataaatt aatagtggat attctattta attaaattta aaaagctacc tttacttata
    32281 agtataatta aggtagcttt ttaaatagag gtagtgtaat taaagagaat ttttaaatat
    32341 aaattgtgaa gctttaatat agatgataat atatattttg caaatatgac acagtgtttt
    32401 cgtatttaag atgataaaat aaataggaat taatgatgat attgaaaaaa taaaaataaa
    32461 ggattaatat aagatattaa agagatagag ataaaagtgt taacagaaga tattgaaaaa
    32521 ataaaagatt gatataagat actgaagagg tagaaacaaa agtattaata gaagatattg
    32581 aaaa
//
LOCUS       DAYAKB010000041        32547 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.041, whole genome shotgun sequence.
ACCESSION   DAYAKB010000041 DAYAKB010000000
VERSION     DAYAKB010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32547
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.041"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            251..1072
                     /gene="yidA"
                     /locus_tag="ACGI3L_002244"
     CDS             251..1072
                     /gene="yidA"
                     /locus_tag="ACGI3L_002244"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFG9197947.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            complement(1208..1849)
                     /gene="saoL"
                     /locus_tag="ACGI3L_002245"
     CDS             complement(1208..1849)
                     /gene="saoL"
                     /locus_tag="ACGI3L_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_238476746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(1364..1366),aa:Sec)
                     /transl_table=11
                     /product="MerB-like organometallic lyase SaoL"
                     /protein_id="HFG9197948.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     CUNIMNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLKQKVLS"
     gene            complement(1862..2614)
                     /gene="saoA"
                     /locus_tag="ACGI3L_002246"
     CDS             complement(1862..2614)
                     /gene="saoA"
                     /locus_tag="ACGI3L_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein SaoA"
                     /protein_id="HFG9197949.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            complement(2614..3357)
                     /gene="saoP"
                     /locus_tag="ACGI3L_002247"
     CDS             complement(2614..3357)
                     /gene="saoP"
                     /locus_tag="ACGI3L_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591060.1"
                     /note="Most members of this family are selenoproteins with
                     the selenocysteine residue at the channel-gating position;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(2791..2793),aa:Sec)
                     /transl_table=11
                     /product="ABC transporter permease subunit SaoP"
                     /protein_id="HFG9197950.1"
                     /translation="MDILYKIILLVIIFLVWHFAAKDIGSSLLLPMPVDVIKGFFFCV
                     TDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFSKTFERVLSPVVDSVRQVPIMA
                     WVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVRAISKDYYNAARSMGASPIVIF
                     TNVIVPASLPDILTGSRIAISTGWMSVIUAEFIATSAGLGYSMVQAQTLMHTDVLIGL
                     MIFAALIGFIIDRVLKFINKILCRWRFAD"
     gene            complement(3381..4169)
                     /gene="saoB"
                     /locus_tag="ACGI3L_002248"
     CDS             complement(3381..4169)
                     /gene="saoB"
                     /locus_tag="ACGI3L_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(3954..3956),aa:Sec)
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     (seleno)protein SaoB"
                     /protein_id="HFG9197951.1"
                     /translation="MKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTSGFV
                     INYMVNRDYFENIKVSDIMDIFTINDCUASTMQWALSSEEIDIAIICKDAAKQYVNVN
                     SGFEIVGTVVQNSDIFLLSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAY
                     GLESNLVDGVVIDCIKSIGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYN
                     KSVDALKNKATFKKVLKEYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            complement(4183..5274)
                     /gene="saoX"
                     /locus_tag="ACGI3L_002249"
     CDS             complement(4183..5274)
                     /gene="saoX"
                     /locus_tag="ACGI3L_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding subunit SaoX"
                     /protein_id="HFG9197952.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            complement(5309..5767)
                     /gene="saoC"
                     /locus_tag="ACGI3L_002250"
     CDS             complement(5309..5767)
                     /gene="saoC"
                     /locus_tag="ACGI3L_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Cys-COOH (seleno)protein SaoC"
                     /protein_id="HFG9197953.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            complement(5760..6845)
                     /gene="saoE"
                     /locus_tag="ACGI3L_002251"
     CDS             complement(5760..6845)
                     /gene="saoE"
                     /locus_tag="ACGI3L_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter SaoE"
                     /protein_id="HFG9197954.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            complement(6872..7129)
                     /gene="saoT"
                     /locus_tag="ACGI3L_002252"
     CDS             complement(6872..7129)
                     /gene="saoT"
                     /locus_tag="ACGI3L_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_240067706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(7094..7096),aa:Sec)
                     /transl_table=11
                     /product="thioredoxin-like (seleno)protein SaoT"
                     /protein_id="HFG9197955.1"
                     /translation="MSKILVEFINTUPSCDEHGVFIKKMSEKYADKLEIKLYQAGKDF
                     SYIKKYGIITKGTLIINQKKKYDRLNKDTIERAIVEAINNN"
     gene            complement(7219..7551)
                     /gene="saoD"
                     /locus_tag="ACGI3L_002253"
     CDS             complement(7219..7551)
                     /gene="saoD"
                     /locus_tag="ACGI3L_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE-related protein SaoD"
                     /protein_id="HFG9197956.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            complement(7807..8643)
                     /gene="nadC"
                     /locus_tag="ACGI3L_002254"
     CDS             complement(7807..8643)
                     /gene="nadC"
                     /locus_tag="ACGI3L_002254"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFG9197957.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            complement(8624..9925)
                     /locus_tag="ACGI3L_002255"
     CDS             complement(8624..9925)
                     /locus_tag="ACGI3L_002255"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HFG9197958.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            complement(9938..10852)
                     /gene="nadA"
                     /locus_tag="ACGI3L_002256"
     CDS             complement(9938..10852)
                     /gene="nadA"
                     /locus_tag="ACGI3L_002256"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HFG9197959.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            11270..12727
                     /locus_tag="ACGI3L_002257"
     CDS             11270..12727
                     /locus_tag="ACGI3L_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HFG9197960.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            12950..13378
                     /locus_tag="ACGI3L_002258"
     CDS             12950..13378
                     /locus_tag="ACGI3L_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197961.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            13438..13746
                     /locus_tag="ACGI3L_002259"
     CDS             13438..13746
                     /locus_tag="ACGI3L_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HFG9197962.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(13893..14915)
                     /locus_tag="ACGI3L_002260"
     CDS             complement(13893..14915)
                     /locus_tag="ACGI3L_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9197963.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(15090..15596)
                     /locus_tag="ACGI3L_002261"
     CDS             complement(15090..15596)
                     /locus_tag="ACGI3L_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFG9197964.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            complement(15656..16357)
                     /locus_tag="ACGI3L_002262"
     CDS             complement(15656..16357)
                     /locus_tag="ACGI3L_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9197965.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            complement(16575..17645)
                     /gene="buk"
                     /locus_tag="ACGI3L_002263"
     CDS             complement(16575..17645)
                     /gene="buk"
                     /locus_tag="ACGI3L_002263"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HFG9197966.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            complement(17698..18273)
                     /locus_tag="ACGI3L_002264"
     CDS             complement(17698..18273)
                     /locus_tag="ACGI3L_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HFG9197967.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            complement(18275..20062)
                     /gene="iorA"
                     /locus_tag="ACGI3L_002265"
     CDS             complement(18275..20062)
                     /gene="iorA"
                     /locus_tag="ACGI3L_002265"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043805 - indolepyruvate ferredoxin
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HFG9197968.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            complement(20123..21382)
                     /locus_tag="ACGI3L_002266"
     CDS             complement(20123..21382)
                     /locus_tag="ACGI3L_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9197969.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            complement(21644..23644)
                     /locus_tag="ACGI3L_002267"
     CDS             complement(21644..23644)
                     /locus_tag="ACGI3L_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9197970.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            complement(23652..25482)
                     /locus_tag="ACGI3L_002268"
                     /pseudo
     CDS             complement(23652..25482)
                     /locus_tag="ACGI3L_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            complement(25566..27407)
                     /locus_tag="ACGI3L_002269"
     CDS             complement(25566..27407)
                     /locus_tag="ACGI3L_002269"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9197971.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            complement(27538..27957)
                     /locus_tag="ACGI3L_002270"
     CDS             complement(27538..27957)
                     /locus_tag="ACGI3L_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HFG9197972.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            28270..28452
                     /locus_tag="ACGI3L_002271"
     CDS             28270..28452
                     /locus_tag="ACGI3L_002271"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197973.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            28781..29803
                     /locus_tag="ACGI3L_002272"
     CDS             28781..29803
                     /locus_tag="ACGI3L_002272"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFG9197974.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(29896..30498)
                     /locus_tag="ACGI3L_002273"
     CDS             complement(29896..30498)
                     /locus_tag="ACGI3L_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HFG9197975.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(30515..31663)
                     /locus_tag="ACGI3L_002274"
     CDS             complement(30515..31663)
                     /locus_tag="ACGI3L_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9197976.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            complement(31656..32033)
                     /locus_tag="ACGI3L_002275"
     CDS             complement(31656..32033)
                     /locus_tag="ACGI3L_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9197977.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
BASE COUNT        10707 a         5564 c         3474 g        12802 t
ORIGIN      
        1 taacaatgca aacgatacca ttatttgtaa ttaagaattt tggaattatt gattacaaag
       61 tttttacatt ctcatctcac ataagtaata tttttatcaa aaaattaata ttattaaact
      121 ttctaaatta cttatctctt gatataatag tatacaaaac aaaccatatt tcccactgaa
      181 actttgttca acactagctg tgtcaacgtt ttcacaggaa atttgagtat ataatttatt
      241 ggaggttgat atgtacaaat taatcgcact agacattgat ggaacaatat taaatacaca
      301 aaaaaggatt actcctgaag tctttgagtc cattcaggag gcaaaaaggg ctggggcaaa
      361 agtagttata acaacaggca gacctcttcc tggtgtaaaa gaacttctaa atcaactaaa
      421 tttaacagat gaaggtgatt atgttatatg ctttaatgga gcaattattc aagaagttaa
      481 aagtgagaaa atcatacatg atgtagaaat gagtttagat gattttgatt ttatatataa
      541 taacgtttgt aaaaaatata agactaaaat acacataaat acaatgacaa atttaattac
      601 accaaatgaa acgcctggca aatatacact tcatgaagcg aaattaaata atatagaagt
      661 caaatatata caaaaagata aaattgatga atctattaaa atctgtaaaa ttatgatagt
      721 tgatgaacca gaaagattgg aagaaatcat acagcaacta cctaaaaatt tattcaataa
      781 atatactata gtaaggtctg ctccttttta tctagaattt ttaggtaaaa ctactaataa
      841 aggaactgct cttaaaacat tatgtacgaa tctaaatata cctatagaaa atgctattgc
      901 tgttggcgat gaagaaaatg accaacatat gataaagtat gcaggtcttg gtgtggctat
      961 ggggaatgca cgtaatagta taaaggaaat tgcagattat gttactgata ctaataatga
     1021 aaatggagtt gcaaaggtta taaataaata tatacttaat aaggctatct aatcatctaa
     1081 aaaaactaaa aatatacctt tagatttaaa tacttttcac atccctactc tatactaatt
     1141 tatatagtat ggatattacc tatcattttt atctaaaggt catttttagt ttttcatata
     1201 tgtatatcta tgatagtacc ttttgtttga gtttaaatat tttatatgat tctactattg
     1261 cctcattaat atctaaacaa tatatatctt catcatcaga taatcccgct tcgtttgtcc
     1321 aagcatcaaa atcactcttc gtccagaaga aattcattat atttcagcaa ctagcagccc
     1381 aatttagatg cttatcaaga tttatatgaa gcactcttaa gtttggatta ttcacatact
     1441 caatcttttc attttttata attacttcta tttccttacc tgtagcacta caaatagagt
     1501 ttatttttat atcttggttg aatgtgcaag aggttcctat agcatctata gcacacattg
     1561 cactgaaact tctattatct ctcaaagtta ctttatgatt tgttggcaat gctgatacag
     1621 gatatataaa atttatacta ttcccatcaa caaccattat atttttataa ataaaatatt
     1681 gtagtgtcct ttctatatat tctttttcta tattcaactt tttacttaca tattcagtca
     1741 cttcttgaag tgtaacacta gaacctttat ctattatcat atccataata gagattctta
     1801 ttttctgttg tgtattatcc aaactattgt atttttctat ttgactcatg tctactcctc
     1861 tttaaacttc ataacacttt gataaagtat cagttaattt gtttttgtac tcttcatatt
     1921 tttggcttcc tctaattcta ggtcttggaa tatctatatt tatatcatca ataattcttc
     1981 ctttatctct cgacattact ataactctat cactcatata tacagcttca tcaacatcat
     2041 gagttaccat taatgcagtt attttcttct ttatccatat tcgttctagc tcttcctgta
     2101 aattttgtct catttgaaaa tctacagctc ctaatggttc atccattagt aatacctctg
     2161 gattacatgc taaagctctt atcatggcca ctctttgttt cattcctcca gataattgat
     2221 gcggaaacag tttttctttt cctttcaagt ctgacataac caaaagttct tctagcattt
     2281 cttctctttt ttcttttggt attttctgct gtttcatagg aaatagaaca ttacctctta
     2341 tagttttcca aggaaataaa gcataatttt gaaatataaa agctctatct atgcccggtt
     2401 ttttaactct tttatcattt ataaaaacat ctccacgttc tgatttttga aacccaccta
     2461 ttatagtaag taaagttgtt tttccacaac ctgatggtcc taaaagacag acaaattgtc
     2521 catcatctat atccatactt atatcttcta aaacctttgt atgtactcta ttatttacaa
     2581 atgtcttatt tatatctctt acacttaact tcattaatct gcaaacctcc atctacaaag
     2641 gattttattt ataaacttta ataccctatc tattataaat cctattaaag ctgcaaatat
     2701 cataagccca attaatacat ctgtatgcat taatgtttga gcttgtacca ttgagtaacc
     2761 gagaccggca ctcgtagcta taaactcggc tcagataaca gacatccatc ctgtacttat
     2821 agcaatcctt gaaccagtta gtatatctgg aagagatgcg ggaacaatta catttgtaaa
     2881 tatcacaatt ggcgatgctc ccatacttct agctgcatta taataatcct ttgatattgc
     2941 tcttactcct tgaatagtat ttaaaattat agggaaaacc cctgaaaaag ctattaaaaa
     3001 tattgttgga ccatctccta taccaaacca tactatagta agaggaaccc atgccattat
     3061 tggaacttgc cttacagaat ctactactgg agataaaacc ctttcaaaag ttttagaaaa
     3121 tcccataata aatcctattg gaagcccaaa caataatgca tacataaaac ctttaagtac
     3181 tctctgcaat gttataaaaa gattagtgac tgtctctgca tctgtcacac agaaaaagaa
     3241 accttttatt acatctactg gcattggaag taacaaagaa ctccctatat cttttgctgc
     3301 aaaatgccag actaaaaata taataactaa tagtattatt ttatataaaa tatccatact
     3361 accatcagtt tttttcttag ttaatctatc gcttttatct ttagaaattt taatttccaa
     3421 ttgcttattt cctccatatc tatatttctt atattcctgt actcttttaa tactttctta
     3481 aatgtagctt tattctttaa agcatcaaca cttttattgt aaagtgttat aaaatcacta
     3541 tatgctttac tttttttaaa ctctttattt acaactaata cataggtatc ataatctcct
     3601 aatttagttg tagattttct tttaccctct aacccaattg actttatgca atctattaca
     3661 acaccatcta ctaaattact ttctaatcca tatgctagtg cagtccctaa taagggagct
     3721 acttccacat tcttgtagta ttttttaacc aattctgact ggtaatctct attttgaatg
     3781 actcctatct tttcaggatt attatcactt aatagaaata tatcagaatt ttgaactaca
     3841 gtaccaacaa tttcaaatcc actatttaca tttacatatt gttttgcagc atctttacat
     3901 atgattgcta tatctatttc ctctgaactc agagcccact gcattgtact tgctcagcaa
     3961 tcattaattg taaaaatatc cattatatca cttactttta tattttcaaa gtagtctcta
     4021 tttaccatat aatttattac aaaaccagag gtatcatcag atacccctat tcttaatttt
     4081 ccttttattt cttctttatc ttcaaaatta aaaaatatta taaatatact tcccaaaata
     4141 atgataaaaa gtattattat atttttcata ttctccattt atttataata cctttgcttt
     4201 ccagtcttca taactcatac cttcaggaaa ctctgggtta actttttctt ttataaattt
     4261 gtcaaaatca tcagctccac aagagtccaa taagcttgta tcaatcgtat cttcatattt
     4321 aggtatatca tctaaagcct ttaaatcttt atacatttgt aaattatttt tatattcttc
     4381 acctgtaact ttccaagtaa gagttctacc ttctccaaca gtcttcttat agatagttct
     4441 aagtgcaact tcttcttcta cattataata ttttgcaaat attttagctg cttcagctgg
     4501 atttgtatat atatattcta ttgcttttgt atgtgctaga accaattttt ttgctaaatc
     4561 tggatgttct tttataaagt ttttgtttaa tgagaatgaa caacagttat attctttgcc
     4621 attagctttt tctttatatt gagtagatgc tattattttt cctgcaccgt cattttcagc
     4681 tacagaaccc caagggtcac aagatgtaaa agcttgaatt ttcccagttt taagagctaa
     4741 atatttatct ttgtctgaat ccatatttac aacttcatat tttgatgggt cagttggtag
     4801 acctgtttct ggaccataat cacttgtcca taagaaatca ctcatatctg ttgcaatttt
     4861 tttacctatt aaatctttag gttcttttat atcttttgaa actattaaat attcagaacc
     4921 accagtatgg ttgttagctg ctattgttat tggcgaaccc ttaggtattg ctccaactaa
     4981 ccccttagtt cctatgtaac ctgcatccat ttttcctgct gccatagctt caggaacttt
     5041 accatttcca acagttttta cattaagacc taaatcttta tatattcctg ccgattctgc
     5101 tactggtccc gcagtcatat ggtcacaatt ataataacct actgttattg tataatcatc
     5161 ttttccagtt tttgcttctt ctttttcttt tggtttacta ctacatcctg ttaatataga
     5221 tgtacccatt acaccaaata agattaatgc ttgaatcttc ttagataatt tcatataaat
     5281 ttcccacctt tatgtattat ttttattttt agcaacattt gtccatatct tcgccaaata
     5341 aatcaacaaa ttttttaccc tctactctgt aaatagcata tcctacatta ccatttttag
     5401 accctgatac aattacttct attggtgctt tatcatcaat atttttaaag gttatcgttt
     5461 gattctctat aggtgctggt attggctttg ttatatagtg gctattttta tcagaaacta
     5521 cgactaccat ttcatttgaa ttattgcttt ttttatatat aactactaaa tctttttttc
     5581 catcattatt taagtcttct tcagcacaag ttattatgtc ttctttataa ttttttctaa
     5641 aatattctaa tgtttcttta ttcacatttg gaatagaagc atcttctttg atgttatcat
     5701 caactatttt tgataaaatg attaacacaa ctactataca ggatattata actatctttt
     5761 taagcatgat ttcctatgac ctctttcatc tttggtatta ttgatttaaa tgcaaataaa
     5821 ataattaaaa tagtacatac atactcaaaa ctatcaggta tatttaacat tagtttattt
     5881 gccaactgta ttgaagaatt tgttgcatct aaatttactg agttattatt cactaaaagt
     5941 aaatttgtta tatatccaat tattattgaa gacagtgtca aagttacaga atatataata
     6001 acagttcttt ttccaataag tttaaacata cttataagtt ctggtagatt tgtagctgct
     6061 ccagctatta gaaatgttat cgctatacca ggagatgctc cacttgcaac aagggctgct
     6121 ataaacggta tatgtcctac agcacataca tacataacac atgcaagtat tgctatactt
     6181 ccaagagata gcaaacctgg atttcctaaa tatttttgaa ttatactatt tggaaaaata
     6241 gttgttataa atcctgcaaa aaccataccc attactacat atttactaat agtaagggct
     6301 aattcaccaa aagaccattt aagaccatca atcatatttc ccataaaact tcttttttct
     6361 tcttctaatt ctattacttc ttcctctgaa tcattatgaa gtgataattc ttcttttcca
     6421 aaacaatttc ctaaaaatcc tactaaaaat ggtactaaaa aaccagctat tagataaatg
     6481 attgtaactt taggacctaa aagacctaga caaagaacta cagctattgg atttattatt
     6541 ggagttgatg tcataaaagc aagtactggt cctaaatatg ctcctgaata atacatactt
     6601 attccaagtg gtattactcc acaactacat attggtaaaa acattcctga gatagtactt
     6661 ttaattaaag aagaaaattt cttatttcca agttgttttt gaaaccttct tggagttaaa
     6721 acattgtgaa gtacacctgc caatataaaa cttatcataa gccatcctga tgctccattc
     6781 agtgtaacta tagaagctac tatagtatct ttaactccat ttaaaacaat ttctaatata
     6841 ttcatttttg atactcctaa tttttaaact tttaattatt gtttatagct tctactattg
     6901 ccctttcaat tgtatcttta tttaatctat catatttctt tttctgattt attattaaag
     6961 ttccttttgt tataatccca tattttttta tatacgaaaa atctttccct gcttgatata
     7021 attttatttc caatttatca gcatattttt ctgacatttt ttttataaac actccatgtt
     7081 catcacaaga tggtcaagtg tttataaatt caactaaaat tttagacatt tgttaatccc
     7141 ctactttaaa caatttatct tttacttaaa ataatccaca gaaaataaat ttttctatgg
     7201 attgtatcct atactaattt ataacgttat aacttggtcc acacctgcac tgcctaaaca
     7261 agcatatagg tttgggaaac atccaattgt agctccatca accaaattat tctctatacc
     7321 tctttctata gcacattggt cacaagccat tattatcata tcagtttttt catgtaattt
     7381 acttagtctc tcgcctacag gattaccttt agataaaaat aaggtattat ccataaagaa
     7441 aaacatccct agaacgtcta ctccatgagt tccttgttca agttgtggta ttatcatttt
     7501 gtctagaatt ttatgtgtat tagtactact aaaaatataa gctactttca tttttattcc
     7561 ccctatactt tttatatttt acaaaatttt acagatacaa ttatattata agtttattct
     7621 tatttatctg taaaatagat attaactata ttattaaaag tgtatatagt atttatctat
     7681 ttttattaaa ttattgattg atttttttct atttttatta attttaatga ataaaaaata
     7741 gactccttaa atttataaaa caaatttaag gagtctattt taattaagtt tatttcaata
     7801 taaaatttat atatttctca aattcttcat acttatatcg agagctttaa cagaatgtgt
     7861 aagcgctcct acagaaacaa catccacacc aatttttcct atatcttcta tagtatctaa
     7921 atttacattt ccggaaaatt ctacaatggc tcttccattt ataatatcta ctgcttgttt
     7981 tgccatttcc aaactcatat tatccaacat tattatatct gcattagctt ctattgcttc
     8041 ttttaccatg tctaaagttt ccacttccac ttctatcttt ctaacaaaag aagtattttt
     8101 tctagctaat tcaactgcct tcttaacact accagcagcc ccaatatggt tgtctttaag
     8161 caatattcca tcagataaat taaatctatg attgcatcct ccacctactt taacagaata
     8221 cttatctaat attctaagat taggtatcgt ttttctacta tctaataatt ttgtatttgt
     8281 accttcaagc ttttcaacat acctacttgt aatagtagct ataccactca ttctctgtaa
     8341 ataattcaat gctacacgct ctcctacaag taagtttcta gtactacctg ttaatacagc
     8401 tatcttttca cgattcttta ctctatcacc atcattttta tataatttta catctacatc
     8461 accaagtatc tcaaaaactc tcttaaatac acctaagcca gctattatac catcttgttt
     8521 acaaattaaa tctacagtag atttagaatt ttcatccaca atagaattag ttgttatatc
     8581 ttcacttgga acatcttcta tcaaagcatc ctgtatcatt ctatcaataa tcaaataatt
     8641 catcgccaaa atcctcactt gttctttcaa tttcttttat gactaatatt ttattttctt
     8701 tttttacctg ttctatatct atatccatat ctggtacatc tataaactta acttttacat
     8761 tatctataac tgagtttata tttttagctg ctctttttga aaatacaagc ccttcaagta
     8821 atgaattact tgccaatcta ttggctccat gaacacctgt acaactaatt tcaccaactg
     8881 catataaatt ttccatagat gtttttgaat ccaaatctac atgtatcccg cccataaaat
     8941 aatgttgtgc aggagatacc tttatacatt ctttcgttat gtctgttcct ctagctaaac
     9001 attcattata aataaaagaa aatctattaa ttaaatattc actatctaaa tgtgttgcat
     9061 ctaaatacac ataaggtaat ttatcttttt ccatttgctc aaaaatagct tttgaaacta
     9121 catctctagg aagaagttca tccacaaatc tttctttatt tttatttaaa agtttagctc
     9181 cctctcctct taatgattca gatataagca ttctcctacc ttcattattt tcttcataaa
     9241 aggctgtagg atgtatttga atatattcta aattttctat ttttatatta tttcttaaag
     9301 ctattgcaat tccatcacct gtaagatgtc tttgattagt agaattttta aaaagcccac
     9361 caattccacc tgtagctaaa actactattt ttgaaaaaac atgaatctct tttttagatt
     9421 taaaaattct agctcctata catttattgc catcttttaa tatatctaaa agataggcat
     9481 cttctataag agttatattt tctctagttt tagcttcttt taataaagtt ttaaaaacaa
     9541 cttctccagt attatcctta ctatgaacta ttcgatttac actatgtgct ccttctcttg
     9601 tgtaatctat ctctccattt tctttgtcta aaggcatacc atattctact atctgcccta
     9661 cattttctat agattcatct gcaagtactt gaactgcttc aactctattt ttatactgcc
     9721 cagccttcat tgtatcttct acaaaggatt ctatatcatc aatatttcta gcagttgaaa
     9781 ttccaccttg tgcaagatat gtattgttgt tttcaattgt tgatttcgat actactagca
     9841 catttaaact tttatctaaa tttaatgcac agtataatcc tgaaactcca cttccaacta
     9901 ttaaaacatc ttgttctaaa ttcataagtc tatccctcta tccttctgct aatttgtgca
     9961 tgttaagcag tgaatttaaa gccttttcca tgatttcatc ttctacaata acttcatttt
    10021 ccatattttt aagtgtacta tataaatttt ctaatgttgt ctttttcata tctgtacata
    10081 gtatttttcc accaggaata taaaagtttt tattaggatt atttttcttt aattcatgta
    10141 atataccttc ttcagttgct attataaagt ctttgttttt actattagta gcatatttta
    10201 ttattcctga tgtactacct acataatctc ctaaatctct tatttctttt ttacattctg
    10261 gatgtactaa tacttctgca tttttatact tatcttttaa ctcaattatt tcttcagctc
    10321 ttatattgtt atggtattta caatatccgt cccaaaatat aaagttttta tctggaaatt
    10381 gttctgcaat atatcctcct aaatttttat ctggaaggaa tataatttct ttattatcta
    10441 tgttttctag tattttaatt gcactagaag atgtaacaga aacatcacaa tgtgccttaa
    10501 ctttagctgt agagtttata taacatacaa ccaaagcatt tggatactgt tgttttaatt
    10561 ttatcacgcc ttcttcatct accatatctg ccatagcaca cccagcgtta cttactggca
    10621 tcaatacagt tttttcaggt gataatatct tagcactttc tcccataaac cttactccac
    10681 aaaatacaac cacttcttct ttacaatctc tagcaatctc acttaaataa tatgagtcac
    10741 caactgcatc tgctaattct tgtatttctg gtggttgata aaaatgggca agtattattg
    10801 catttttttc tttctttagc tctttgattt gatatgttaa atctttatcc ataattgcac
    10861 cgctttctat atgtactagt gtatatacac ctgtaaactc attatatcac ttgactattc
    10921 tttcttcaag aattttaaac ctcttaatat tgttaagata tagacattta tattctcaat
    10981 tgattttcct tttttctcca tctatttaaa ctaattttta tattttttaa tttttttgta
    11041 aaatattatc agaattttgt ctatattctt tattgctata acattgaaaa tattaccaaa
    11101 tacctgtata ctaagtacat ggttatgtat atgtatttat ttctgaaatt atattagttg
    11161 taatacttta tagaatttgt aggttgtcca gaattaaatt caatataaat ctacacattt
    11221 agataatatg tatacaaaga ccaaaaaatt ttataaatgg ggtgatatta tgacaacatt
    11281 cttaatcggc ttggctatat tactaatagg aggtgcttta tacggtgctt attgtgaaaa
    11341 agtatttggc ccagatgaca gaaaaacacc tgcacttgct caaagtgatg gagtagacta
    11401 tgtcccaatg aaaaaatgga aaaatagtct aattgagttg cttaatatag ctggtacagg
    11461 accaattcta ggacctatcc aaggtatatt gtttggtcca atagcattca tactaatacc
    11521 tattggctgt gtatttggag gagctttgca tgactatatg agtggaatga ttagtataag
    11581 agaaaaagga gcacaaatgc cttctcttat cagtagattt ttaggtaata aagtatttca
    11641 agtctataat atattccttt gtcttttaat gcttttagtt ggtgcagttt ttatttatac
    11701 acctggggat ttagttgtta ctcaaatttt aaatatgaaa tcgactataa ataatccagt
    11761 tgtctggata gtttatggac ttatctttct atattacttg tgtgcaacac tatttccaat
    11821 tgataaaatc ataggaaagg tatatccaat atttggagct attctacttt tatctgctgc
    11881 tggtgttgga attggaatct ttacacaagg ttatgattta gctaatttaa gtcttgcaaa
    11941 ttggaaaggt attcatcctg atggtattcc tcttattcct acattctttg ttacagttgc
    12001 ttgtggtatt gtttctggat tccactcaac tcaagctact cttatagcaa gatcagtttc
    12061 aaatgaaaaa gaaggaaaaa ctacttttta taatatgatg attttagaag gtttaattgc
    12121 aatgatttgg gctgcagctg ctatgggtat ttacaataaa ggaataccta aggaattagt
    12181 aggttctcct gatgtaatag gtttggttgc aagagattta cttggttcta ttggtggtat
    12241 catagctata ataggtgtaa ttgttttacc aataacttct ggagatacag ctttaagatc
    12301 tttaagatta atgcttgcag attactttca ttatgaccaa aaggaaaaaa aacatcgtgt
    12361 tatattgtca atctgtatat ttattcctgt catagccatc cttatatttg caaagcttag
    12421 tgcttctgga tttaatatat tgtggagata cttctcttgg agtaatcaaa ctattgccat
    12481 atttgcattt gcaatgatta cagtttacct tataataaaa gaaaagaatt atattataag
    12541 cttaattcct ggtatgtttt attcctttgt tatattcagt tatatattta atgctcaaat
    12601 tggatttaac ttaaacataa atatatcata tgttttagct gccatattta ctgtattata
    12661 tgctatttta actgtacgct ctggtagaaa gttaaaaagc aaagcagata ctaagttggc
    12721 tgactaaatc taaataaaat aatacttaga ataaatttta ttaaaaaatg ataaaaaagt
    12781 aggcaatctc aagttagatt tgcctctttt ttatttaata cagtaataaa tacttaagta
    12841 tttactcctt attggaatat ttatcctaaa tctctaatat aaataaataa aagttttaaa
    12901 ataatctatt cgtttatata cttaaaataa attttttgga ggaatactta tgaataataa
    12961 attacatgaa cttgaaaaaa atctaccaga aacatcttgt tctttttgca cacatctttc
    13021 atttaagggg cctagcctag actatagata tgatattaga tgtgttattt cagatacaaa
    13081 gcccgatttt agaggatgtt gtgaatattt tgaaccagaa tatacagaat taaatacagg
    13141 agatttagac aatctataca taaactttct tgagacatgc ctcaaggtaa attataatga
    13201 ttacatcaat tctatgtatt ggaagttatt taaagaaaga accctactag aaaacaattt
    13261 taaatgttct atatgtggat caactgaaaa tgttgatgtg tatcatgtta ataaaaattt
    13321 aggaagggaa acttccaaag atgtagttgt taaatgtgat aaatgtaatt gtaaataagt
    13381 gtataaaatt tagataactt cacataataa gtttaaataa aacttaggag gttatttatg
    13441 aaaaataata atttaaattg tgctgctact aattgtgctt ataatactag tggatattgt
    13501 tatgctggta gtataaaagt agatggaatg caagcaacta ctacagaaaa tacttattgt
    13561 gcttcttttg aagacaaata tacatctggt ataactagtc gttctaatga aactaaccaa
    13621 gttgatacag ataacattca ttgtgaagct gtaaaatgta aatacaataa aaatgaactt
    13681 tgcaaagctg aaaaagttca tataaatgaa agaaatgcaa gttgtgaaac ttttgaaatg
    13741 aaataaattt ctttttattt agttttatag tatttataca aagcaaaatt gaacctatca
    13801 aatagatgtc tttattaatg atgtctattt ataggttctt ttttaaaaca atttataatt
    13861 tatatataaa gataaattat tattttaata tattacctag aagtaaattt aacacccaga
    13921 atatccataa ggaacataaa tattggaact ccaattagta atccccatac acctaaataa
    13981 tgttctccta caagtaaaat aataaaaaca aaacaaactg gaagtttagt tctattcgac
    14041 atcaacttag ggtttaatat gtatgtttct actgcatgca ctatacaaat cataagtaaa
    14101 actccaaaaa cctttgttat tcctcctgta ttaaatgcta ttacagttaa tggaatcaaa
    14161 gacactataa ctcctgctac tggaataaga cccaacacaa aaatcataaa tcctaaagcc
    14221 catatttgag ggaatcccat gaaacctaag aaaatcatag aaacaacaga atttataaag
    14281 gcaatcataa cttgtacttt cattacttca ccaaaatttt taacaaagct ctttccaaaa
    14341 aatacaagcg aattataaat aaaagaaatc ttactatcag aaagtttatc tccaaaattt
    14401 ttaatttcat ttttttcaag taaaaggagt aaactcagta aaaatgccaa taatatattt
    14461 actccaaaac ttccaacttt tgttgctgtt gatgctataa gtagccctgc ttgtgaaata
    14521 tatttattaa aatccagctt tgagacaata ggatacaatt ttggtcctaa agattgagca
    14581 aattgattta catcaaaatc actaaaaacc ctactcaact ctgtaagttg aactataatt
    14641 attggtacaa ctgcatagct aatcaatact aacaatatag caaatagtgc atataacact
    14701 ataattatta atgaatctgg aatatttaaa gaagaaaact tcttaattcg ttttcttgtg
    14761 gctacaagca agttatagaa aataaaagtc ataataaatg ttaaaagcac catatttaac
    14821 atataccaaa atgtaattag aataattact acgacagata tagaaacaat tttatatttt
    14881 gaactgtcac gtgccaatcc tttgttatct tccatagttt aaatcctccc caaattttta
    14941 tgactttata atgactgccc tttttatttt aatctcaaaa aacaagtaga aaaatactaa
    15001 aaataactta ttaattttca taaaacaata ttaaaattta gagaagatac attttaaata
    15061 atcttactta tactgaaatc tgctctacat catatattta atttattatt atctatctca
    15121 tatagcaatt cgtatatctc tggatattca aaaaacaaac cctcttttag taattgtctt
    15181 atttcatctg tgcttaccca ctttatatca cttacttctt cctcctgtaa aatagctttg
    15241 gatatatcat attctttttt aactaagtat acatcccaaa gagtatcttc atgaatcata
    15301 cttctaaaaa ctttcatctc atctttagtt atatctatcc ctatttcttc ctttgcttcg
    15361 cgaattgctc cttctaaact gtcttcccca gaaacaatac atccagttgt cattccccac
    15421 atatttggca atgtcttttt acttttagac cttttctgaa ttaaaatttg agagttacta
    15481 tttaaaatcc acacttcaac tgccaaatgg taataacctt cttcaataga attacctctt
    15541 tttataacat ttcctgtttt aattccatca gcattatata aatcccataa ttccatttca
    15601 aaatctcctt gactttacta taaattagat aaactacaaa tatattttag cataattaat
    15661 tctgctcatt ttttattaca atacttgatt tacatttatg ttcattgctt ttcttttcct
    15721 tccattctct tatatcatct ataataaatc tatgtttcaa caattttgtg tcaaatttaa
    15781 atattctaaa cactatttgt aatacatatc ctaaacctaa agcacttaca agcgtaccaa
    15841 tacctacaga acctcctaat aaccacccaa caactaatgc tagtatttca agaattgttc
    15901 taacaagacg tacagattta ttagtttttt tctgaagagc aatcataagc ccatctctcg
    15961 gtccacttcc taaacaaaca cctaagtata gaaaacttgc tatagctgcc aaaataattc
    16021 ctataacaac cataaacaca cctatataag tgttgcttgc atgaggtatc actccagaaa
    16081 atattactaa atcaataaaa attcctataa atgtcatgtt gagtaaagta ccccatccta
    16141 tattttcacc aaaaactgca tccaatataa caattacaac tcctaccatt atagaagcct
    16201 gacctatagt tatgcctagc tttatagata aaccttggtg aagtacatcc caaggcataa
    16261 gacctacatg tgcattaatc ataagcacag aagaaattgc aaatataaaa aaacctgaaa
    16321 ataatcttat catacttttt aaacttattt ttcccatcaa aaatcactcc tcataataat
    16381 aataacaata aataccaata aaatatatat ataaatacga aattttacag aattatttat
    16441 taggttaaga taaaatttta attataaaaa gtggcaatcc aaattttata cattttcacc
    16501 tatactctaa gctttcgtgt ataaaaaacg gatataccac ttttttagta tataaacatt
    16561 tttagttttt cttattaatt ttcactataa attctagctt cttcttctcc atttagtact
    16621 cttaaagttc caaaagcaag tgattccaac tcattttctc ctgccataat ttctactggt
    16681 gctataaact caactttctt tttaaccatt gaagtaaaca tttcagaata tgcaattcca
    16741 cctgttataa ttatagcatc tacctttcca tctactacag ttgctaactc tccaatacct
    16801 tttgctaact gataagccat tgcttcataa ataatttttg cttcttcatt tccttctgct
    16861 atcatttttt caacttctct agcatctaca gtatttaggt atgaaactat accaccttta
    16921 cctcttatct ttttagtcat ttctctttct gaatattgac ctgaataaca ggcagccact
    16981 aattttgtag caggtactct tcctgacctt tctggagaaa atggtccttc atcatcagat
    17041 agcatatcaa ccattcttcc tttttcatga agataaatac ttactcctcc accaatgtga
    17101 gctactatta agtttaagct cttataatct tttcctttat ccttagcata ttttaaagcc
    17161 attgctctag tatttaatgc atgccctgca cttgatctat ccattccaca aagtccagat
    17221 attctcgcta catctataag ctcatctact gcaacagaat cataaatata tgagttgatt
    17281 ccaagaggtt ctgatattgc atgtgccaca acagcaccta aattggaagc gtgttcaagt
    17341 actggtctat gtcttagtac atcaatcatt tcttcattta ctaaatatgc tcctgatttt
    17401 actggtggta aaactccacc tcttcctact attgcactaa gagattttaa gtctatacta
    17461 ttttctttaa gaatattcaa aactgcttcc ttacgcattt caaactggtc ttgtatagta
    17521 ttatattttg caatctcttc agctggatgg tctatcgtct tcacaagaat ttgttcttct
    17581 ccatcatata ctgctatttt tgtagaagta gaacctggat ttatggctaa tattctgtaa
    17641 gtcataattt tcttcctttc accttaattt ctatagtcta tttatatcta ttataaacta
    17701 tttgctaacc atttccatac cttcatggaa agcttttatg tttaattcaa caaattttgg
    17761 tttaacattt tcacttataa ttttttccca atcaatagac tctaattgca tagatttaac
    17821 tagacatcct aataaaataa cattcattat ttttgaattt cctagttctt cagctttatc
    17881 agctgcattt ataacttttg catttaatct acttaactct gcatctatat cactttcttg
    17941 atattcagct cctccgatta aaacagtcat agaatctatc ctatgattat tcactaaagc
    18001 ttttccttct ggttttaaat aattgaacca tcttaaagct tccatttttt caaaagatac
    18061 taatatatct gctccaccaa tttctataac tggagaatga acacaatctc catatctaac
    18121 ttgtgaggaa actgaacctc ctctttgact cattccatgt atttcactca tctttacatc
    18181 atatccagct tccatcaatc ccatagttaa taatttacta gcaagtatag ttccttgacc
    18241 tcctacacct accaaaagta tactcttagt catattattt ttcctcctta actattgctt
    18301 gttttggaca aacttgtgca catactccac atcctacaca ctgatttcta tctatatttg
    18361 ataacttatt ctctttatca aatgatagag ctggacatcc agttttcaaa cataatttac
    18421 atcctataca tttatcatgg tcaactttac acttagtctt aaatggatta ttaaattctt
    18481 ctatatcttc tttagagaat tttttaagta cacatggcca tcttgttatt attactgatg
    18541 gttcatcttc tatagctaaa gcccaatcta gtgcttcatt tacttctttt aaattattag
    18601 ggtttataac tcttacatgt tctattccac aagctttaac taatccttct atatcaactt
    18661 ctttagtttt agcaccttgt aaagtatatc ctgaacctgg gttttcttgg tgacctgtca
    18721 ttccagttat tctattatct aatataaccg aaatagaatt acctctattg taaacaacat
    18781 ctaaaagtcc atttattcct gtatggaaga atgttgagtc tccaagtaca cctaccaatc
    18841 ttttttcatt atcatccttc atattaagaa ctttttgagc tccatgtgca gttccaaaag
    18901 cagaacccat acaaacaaca taatctattc cattatatgg aggagcaaat ccaagagtat
    18961 aacaacctat atctccacca actattaaat tttttctctt tccaagttca tagaagaatc
    19021 ctctatgtgg acatcctgca cagaaacttg gtggtcttgg tgttactaat tcagatttgt
    19081 attctatagt atcatttgtt tttccaaata tagcttttct taaaacatct ggtgtcattt
    19141 ctccatatgg tggtattaca tcttttccaa tacaatctat tccatatgct tttatttgtt
    19201 cttctataaa tgggtcattt tcttctataa catatatttt atcaactttt tctgcaaatt
    19261 cttttatttt ttcataaggt aatggatttg taaatcctag tttcatatat gatgcatttt
    19321 ttccaaaaac ttctttggca aaattacaac acataccaga tgctataaca cctatttttg
    19381 tatcatttat ttcatagtag tttaaatcag tttcatttga gaatttttta agaatttcca
    19441 ttctttcttc aacaacgccc cttcttattt gagcatttgc tggaacagtt accattttct
    19501 tagcattttt aacatactct ttaatttcaa cttcttctct atcatagcac tccactaatc
    19561 cttttgaatg acaaagtctt gttgtaactc tatataaaac tggtgtatcg tatttttcac
    19621 taacttcaaa agcttctttt atcatatctt tagcttcttg actagttgat ggttcaaata
    19681 aaggtatctt tgcaaatttt gcatacatcc tattgtcttg ctcattttga gatgaatgca
    19741 ttcccggctc atctgctgta ataagtacca taccaccatt tacccctgta tatgcataag
    19801 taaatattgg atcagctgca acattcaaac caacatgttt catagaagcc attgttcttg
    19861 ctcctgcaat tgaaccccct atagcagcct caagtgctac cttttcgttt ggagcccact
    19921 ctgcaactat tgcatcttta tatgttgcta tattttctaa tatttctgta cttggagtcc
    19981 ctggatatgc agatgcatat ttaacaccag cctcataggc tccacgtgca attgcttcat
    20041 tacctgtcat caattgtttc atataaaatt ccctccatct acaattatta aattcatagt
    20101 ccacccaatt tgttcaatga aattaattat ttatttttac ttctaaactt tcaagtgctt
    20161 cttttataat acttggtgct ttcttacatt tatcttcaga aactgcacaa actgcaaatc
    20221 ttaagcccat ttttaatgga actgcaaata aattatgttt agtcaattct tcacatactt
    20281 cttttggatt atcacatggt atacttacaa agaaacctgc tatatatgga agaatttcta
    20341 atcctactct ttcagcttct tttacaaata catctgctct tctagtaagc atgtttttgt
    20401 atatttcttt ttcatcctca tattctttga attttttagg gtcatttaca atgttagata
    20461 atactgccat agcacttcta ttacaatttg accaatttgc tctacatgaa tgaacacatg
    20521 agtaatggaa ctcttcagct acatcttcac ttgaagatat acaaattata gctcccattc
    20581 tcataccata agctgtaaat ccttttgaca tactgaatcc aaccaatacg agaacgtttt
    20641 caggcaaatt agaaaatttc ttaaaaaact ttctacatac atcatcatca cctgcaaagt
    20701 caatatatgc tgaatctacg aaaaatatta tctttttgtc tttatctttt gcgacttctt
    20761 ttgataagtc taatatttta tcccactcat catctgcaac actatatcca gttggattat
    20821 gcgctggtgt gtttataatt gtaaagactc taccttgttt ttctgctata tttacaaatt
    20881 tttctttaaa cgactcaaaa ttaaaccttc tattttcatc aaaaagttgg taattaacta
    20941 cttttctatt agcctcttca gctatactta catatggact ccagaaccaa tcagatgtta
    21001 atacctcatc tccttcatta gtatagttcc atacagctaa ttttattgca ccacttcctc
    21061 ctggtgaagc taatactctt atatgtcctt ctggtaagta atctctgaaa aatacttttt
    21121 taactgcttc taagtaatct ggttgacctt caagagctgc atatgcacct atctcacagt
    21181 tatctaatgc tttatattct tcatatacag ttttcattgt tatcaatttt cctgaatcat
    21241 ccattagagc gcctattgtt gcatttatta cattatccat accaaaagcc ttctctgctg
    21301 cttgagctct gccagatatg ctaaatataa catcattttc ttttggccac attgcatgct
    21361 taccaaccat actttgactc ataccatcac ccctaaaatt gtatttactc ttacattata
    21421 tattaagcaa ttactatgcc aataaatccc actttatgta aaattgattt tgtttagaat
    21481 tattattttt ttcattatta aattaagtgt tttaactatt tttcttataa atatatatgc
    21541 ctgtctaaaa aaataaaaat ttgcaaaaaa gtaatgttaa tttttcttaa cacttgtttt
    21601 aaaaaattaa cattacttca aaataattta tatgtaatta tatttaaata tttttattgt
    21661 atttcttcca taaagatgtc ctgcttattc caagaacttg tgcaacttca tttttagaaa
    21721 gtccctgagc aaaaagcata cttattattt tttcttcaac atacttattt acttctttta
    21781 tatctatact tatcttacca tcatttatct tacttatatt tatagattca tcttggactt
    21841 ctacacttgc tgtcgtttca gaattaaatt tgtctacttc agagttagga agtaattttt
    21901 tagttttaaa atctctatct tgtctcaatt taattttacc tgtcacaaca tatttttgag
    21961 ctattgtctt taactctctt acatttccag gccagctata attatatagc ttatccattt
    22021 catctttagt caaaacaaaa ttttcatcta tactgtttat tccattgaga ccatcatcct
    22081 ttaatacttc atttacaaaa ttgttaaaca aaggtattat atcttctctt ctgtctctta
    22141 aaggaggtat atttatctct aaactactca atctataaaa taagtctgct ctaaatgtac
    22201 ccataactat tttttcggtt aaagattcat tcgttgctgc tataatcctt atatccagag
    22261 gtattatata atcagaacca attctcatta tttgacgttc ttctattact cttaatagtt
    22321 ttgtttgaat attaaaggat agactattta tttcatctaa aaaaagagtc cctccatgag
    22381 caagttcaaa tagtcctctt tttccaccct ttctagcacc agtaaatgca ccttcttcat
    22441 agccaaaaag ttcactttca agtaaatttt ctgctatagt agcacaattt atagcaacaa
    22501 aaggcctatc ttttctttta cttatgttgt gtatactatg agctataatt tctttaccag
    22561 acccactttc tccataaagt aaagttgtat aatcactttt tccaattttt ttagcttctt
    22621 caataaattc tttagttaat ttatctttaa ataaaaaatc atcaaaagta tatctagcat
    22681 agagaccttt ttgattcaag tcaaatctta tttttctttc taagttttgt agcttggtta
    22741 tatcttgtat tattcctaaa actccataag tactattatc aacttttatc aatgttgtcc
    22801 tagtattaac aattagatta tttatatttc ttatctttct atcttctacg tcctcttttt
    22861 catgtaaaca atctaacatc cactccattt taggaaatac atctaagatg tatttattaa
    22921 gtgcacattt tctctctact ttaagcatgt tttttgcact ttcattgtac aaaattatac
    22981 tgccattact atctatagca attactccat cttttatacc atcaagtata tttcgtaaca
    23041 cttcattatt aaacttttct tcacctaatg tatctaataa ttttttacaa tattctacag
    23101 cttctcttat agattcatca ctagcagttg caaatacact atcaattcca tattgccttg
    23161 caaaagaaca tgccaaacct cctcctacga ttacaacttc atctttttgg tctatatatt
    23221 ttacaacttt acttcttatc tcatacttag attcaaacca ttcttcagtt atttcagtac
    23281 ttatgacatt tctccagcca acatagtcaa aagaaacttc attgtctcca agaatcaata
    23341 ctactttttt agaatatttc tttgctattt ctattgctct taaaaggtca gttgacttca
    23401 tattcattgg tataacaggt acatttactg tatctattac taagctataa cctccacctc
    23461 taccaattat agcttgggca cctttttcaa caagtatacg accttgattt tccattaagt
    23521 ctaggttaag tatgtcgatt attatagttc cattttctac atcttctcta tataattctt
    23581 ctattctttc ttttaattca atatcagagg ctataattcc tatttttttt cgcaacaaaa
    23641 tcacctcaat tttaaattat aatgtattga tttctacctg ctttttttga tttatatagg
    23701 ttcttatctg catcttcaat taatatttca acatcttttc tactacgaca cctttttata
    23761 cttactccag cacttatagt tatatagttt tttattttag aatatatatg ttcaataccc
    23821 tcaaattcaa gaagtttgaa aactctttta atatataatt ctatattatc aatctcttca
    23881 acaccgattg attctataga atctactaat attaaaattt cttctccccc atatctgatt
    23941 atgtgttcgg taatatctat aaatacactt cttataatat cagttacctt aactataact
    24001 ttatcccctg ctagatgacc ataattatca ttataacttt taaaacaatc tatatcgacc
    24061 agtattgcga ccatattttt gtctctggtt ccattaaata aatccaactg ctgttccaaa
    24121 tatcttctat tatatagttt agtaagtcca tcttttaaaa tatcattttc taatttctta
    24181 ttatcatcca ctagtaatct taaactctct tgtttttgtc tgagttcata ttgtttgtga
    24241 attgcttgag atgttttata ggaattattt ttttcccacc tatcagaata ccaatccata
    24301 cttttataat attctattgc cagtttaaaa tcttttttta gctcatatcc atttgctatt
    24361 agcccatata aatatagata tttttctaag attcaatgaa ctctttttaa ctaaatttaa
    24421 accttttata taacaactta taccttcatc tatattacca aattttatat ataaatctcc
    24481 atacaactta tatatgtaat ctagtttaga attatatata aaaacatctc caaaactttt
    24541 atatatattt tttgataaaa ttaaataggt gtttaccttt tcaaaactac aattatcttt
    24601 ctttaactca atttcagctg aatataaaaa tataaatgaa tataaataat ccttatatac
    24661 accttcaaca actttcatta attttatagt ctttaataaa ataacttctg cttctttatt
    24721 catatcttct tttaaatatg cccatataag gtctattttt atagacactc tttcagttac
    24781 tgatattgag ttattactgt gtgcaacatc taatacatta tttatgtatt ttatagcttc
    24841 tacattattt ccactctcta aataacacaa acttattata catttacaaa aagcctctat
    24901 agagtataaa ttattttctt gagccaattt tagacattca attaagtatt ccatactttt
    24961 tataaagtta ttaaataaat atagataaac tctcccaaat atataatttg ccctacttac
    25021 aagagcttta ttttttaaag ttttaaaaaa agacacttct tctactaaag ctattacatc
    25081 cgttttggtc tgatataaag cacttatttc cacacataaa ctcatattta acaataccaa
    25141 caactcattt aaatgatttt gccttataat tttttttgct gagaaataaa aattatttac
    25201 cttatcatat tttcttatag aaatagctga taaagtaaga taaatataaa ttttagatat
    25261 tatatctgaa tcatctttta atgacaattt tttaatatac tttaatgact ctatcaaata
    25321 gttgtatgat gcttctctat ctttttttat atagtttata agactaatta aatataaagt
    25381 atagactcta ctattatctt ctaattttgt atttaaaagg tctttgtgat aatccaagat
    25441 gtagtttaaa tctgtcaaat ttagatagaa tttagtcaac atatcgtatt ctatcttgtt
    25501 tatatttctc tttaaatctt ctattaaact ccttttcaag taaatcacca atcctatttc
    25561 aacagttaaa aattcttaaa atcatgataa tgcaaacatc tatttctacc actttccttt
    25621 gctttatata aagctttatc agcattttca attatttctt ttatatctat actactattt
    25681 ttacatgtat caatgccaat actaactgtc aaattattat ttaaaaattt ctttacaatc
    25741 ctacataatt ttcttccaaa tattttactt tttttataat ctttacatac agataatatc
    25801 agaaattctt ctccaccata ccttatcata agcatgtctt tttttagata tttttttatt
    25861 attatagtta tatttttaag agcaatatct ccattataat gtccataagt atcattgtat
    25921 tctttaaagt aatctacatc tatcataaat gctgtgcaat attcactaac ttcttgtttt
    25981 tctaaaaaat cgttcaaaaa agttctatta tatgcacttg tcaaatggtc aacatacttt
    26041 tttttatcta aatcaagttt tacttttctc atgttattta tttctttttc tatatactca
    26101 tgtctataat ttaaggaatc tatataattt ctatttcgag cttttatata catcattttt
    26161 aactcataat acattttaaa gtatttcata ctcatttcat aattttgaat cttttcaaaa
    26221 cacaaatata tactcttgta tgctaacttc acataattat aatttttagc atttttagat
    26281 ttttcaagga gttttttatt tgtatttaag gcattgtcat aatatccaaa gatataatat
    26341 atctttgcct ggtgataaat tatttctaaa tcatatatta tatattcttc tatatttttt
    26401 atcatattta atatgttttt agctctatct aaatagcata ttgattgttc aaaagatttt
    26461 tcattacttt ttgcataata catggctaaa cttataaata aatcaaactt ctctacttct
    26521 tttaagctat gatttttaat tttttctaga tatacttcag attttgctaa attatttatt
    26581 gcgacaggat aatttctagt ctttattaat attttagtta tgttgtttga tgctctatat
    26641 ttttgaatta tatttacatt tctatacttt ttattgctta ttacttcatt gaaatattcc
    26701 atggaacatt cataattttc aaacgaacat tcacactcac ctatctttat attacatagt
    26761 gaagatactt gcatatcctt tagtaaatct gcatattttc ttgcttttaa aaaatttacc
    26821 ttagcaatta gagcatcatc caaaaacaaa aaatatattt taccaataat aaaaaaatat
    26881 atttttttac aattaaaatc gttaatttct tttatcttta tatacaacgt ttctatttct
    26941 ttaattatta cagaagattc tatacactta cttgccttaa tgtaaataag ttgtgattta
    27001 aaaataattt cttcaattag aaaattattt tcatcacaaa taagattaaa tttatccata
    27061 tataaatttg ccttatttac atcttcattt tttaaactta aaatagctat ttgtgaataa
    27121 aatcgtgcta aaaatttata atctttgggt aagcatttat caatatattt acaggaaatc
    27181 aaaatatact ctttcatttt ttcactaaac ccttgaatac catataataa agctagcaaa
    27241 aaatttgatt ttaataacat taaactattt tgttcagttt tatagcaatc aattaaattc
    27301 tttactacat caattttatt ttcaataaaa tcgttattag tcaataatct ttcattcaag
    27361 gttagtttaa acattgaatc taaaattgta tcatctatct cttccaaata tttactatat
    27421 attgtaactc acctccgact tacattatct cataaattta gtaattttcc atactatttt
    27481 tgaaaaaagt tgatgtctca atttagaaat ttctcttaaa ttaagacata ctttacacta
    27541 aactatacaa ttttctatct gaactatata atcctgacaa ttttcgcaaa ttatcacact
    27601 tacaatataa ctattatcaa ctttatttgc ccttgatagt ttattaaaag atagtccttt
    27661 ataatcaaca gatatattgc ttattacata ttctccatct ttactgaaaa tataaaagtg
    27721 atattctaaa aaaggaaaga attttttctt ttcttttact ccttctaaac ataatggaca
    27781 tgcttcttga taatattcta catcaaaatc aacttcttct gcttcattaa gtatatcaat
    27841 tatttttgaa atacttactc cttgaactgg attttcttca tcatttatta aagcactaca
    27901 gttctcctct tttaataaat attccttatc atcatatata aacttatata aactcatatt
    27961 atatcctcct tataattatt aatctccaag ttattctacc atttaaataa agttaataaa
    28021 agtaattgtt tataatcttt ataattaagt tatgtataca tatattccta tgcgctatct
    28081 taattaatga ttttaaaatc caagtttgca ctttgaacat ccagtttccc aaaatctatt
    28141 gtcaaaactc actttagtta ttaatataat gatataaata tataactgca tagatgttac
    28201 acacttaact atttaatatg atacgatttg gtatctaaat ttatatattg tatatagggg
    28261 gagatatata tgtataaaga taaaagtgat gaatgtatac acttaatgac tgcatacatc
    28321 gatagtataa gtggatatta ttcatttatt gacacacaat tagaggattt tatgatgaaa
    28381 tatggtgaaa acattgttga ttcaaattta cacagtataa tgatgttgct ttgtaaatgg
    28441 ggattatctt agcatttcaa gaaacttttt tgtatattgt attctatatt atttattcat
    28501 taacaaaaaa gattgacata aacttaaaag ctatatatag atttctttaa aaatctatat
    28561 atagcttttt taattttttc aaaatgtata cttaaataag ttagtttttt tcaaaatttg
    28621 actatctaat atgatataat ttaactatct acaacaataa aaaatatcta atatgtatta
    28681 tctagtttag ctcatcataa taacatccct atatttacaa ttaagatatt ttcaatatag
    28741 taatactcaa ttttaatatt ataaaaagga gagattttgt atggattaca atgacttact
    28801 aaaatcagct agagagaact ttaatggaac atgtaaagta tgtaaaattt gtaatggatt
    28861 agcttgtgct ggagatgttc ctggtatggg tggtaaagga agtggttcgt ctttcattga
    28921 aaatagaaaa agtctagaaa aaataaagat aaatatgaga gtcatacata atgtttcaaa
    28981 gccagataca tccatagaat tatttggtag aaaaatgagt tctcctatat tcgctgcacc
    29041 tgtatcaggt actatattga acatgggtgg taaagtttcc gaaaaagaat acatagagcc
    29101 tgttgttaga ggttgttcta attctggaat ttatgctatg gttggcgata ctaatgtaga
    29161 tactttttta ctggataatt tagatgtatt gaaggataat aggggaaatg gaattgtatt
    29221 tataaagcct tggaataatt caaagataat agataaaatt agattgtctg aagaagcagg
    29281 tgcttttgca gttggtgtag accttgatgc ttgtggactt attaataatc aatttcaaga
    29341 aaatcctttt tctcctaaaa caattgatga gattagagaa ttggttgaat ccactagatt
    29401 accttttatt ataaaaggaa ttatgactgt agatgatgct ttgatggctg tagagtctgg
    29461 tgctagtgcc attattgttt caaatcatgg tggaagagta cttgattata ctcctggtac
    29521 ttgtgaggta cttccagata tagctaagtc tgtaaaggga aagataacaa tacttgttga
    29581 tggtggagtt aggactggtg ttgatgtagt taagatgctt ggattgggtg ctgatgctgt
    29641 tttgatggga agaccttttg ttactgcttc ttttggcggt ggtcttgatg gtgtggagtt
    29701 ttttatagag aaggttagga atgagttatg tgagactatg attttgactg gttgtcaaaa
    29761 tgttaaggat atagatggta gagttatatg gaatttattg taaaatagtt ttataacatt
    29821 tatatttaaa tagtgtctca tttaaattga aaaatcatat tgagacacta tttaatatat
    29881 ttttagattt taatcctatg aaagagtagg gtcagttagt ctacccaatt tatcccaagt
    29941 agctggacca attattccat ctgcagacaa accgtatttt ttttggaaac ttacaactgc
    30001 attatatgtc ttacttccaa aagaactatc tatacctaca ttataaccaa gtaaagttaa
    30061 catgatttgt gcagctttta cttcttttcc gctattaccc tttcgtataa cttttgttgt
    30121 acttatagtc aaatactcat tactcataat tgttatagtt ttagcaccta tattataaga
    30181 aacagtataa cttgcataaa cacctttact attgtcctca ttcattagat tagctgattc
    30241 tggaacaaat atctcatcat ctggcttagg gtctatattt atctcttcac aattttgttt
    30301 atgttcatct cttatttctt gtggcgcatt ttcatatgta tatatatacc cagaaagagt
    30361 aaaagaatct aggtttttct ctggaacagt ctctttactt cctcctttct ctttacttgt
    30421 gtcagcaaat gccacacttg taaaagtaag caataagcaa cacataatag ctactatttt
    30481 tcttaatttt gttaacataa aatcctcctt ataattattt tattaattga ttataatctt
    30541 tcatatccat ttctattatg tcatagtctc taggtatttt accttctaat tcgcatttat
    30601 cttcataaaa tttcctaatt tcatttggtg catctttata ataaatattt ataattttat
    30661 cagtcgtctt attcaataaa aattcattaa tattgttatt cattccatta ttaccctcat
    30721 caattctaac ttgagcatca acttcaacaa aagatgttat agaagtcata aatactaaaa
    30781 cagcaattag tattccactt ttgcctttct ttttaacaat actctcaagt ctcttttcca
    30841 aatttgtctt atcaaactcg gttgtcaaaa tcttactatt ataattttta ctaaacttaa
    30901 ttgactttat aagtgctagt gcatattctt ttttatcttt taaagaacat tctaccaaaa
    30961 cactttcatc acaacataat tcacaatcta gatttacttt attgctcatt acatatacaa
    31021 gtggattaaa ccaatatatt attctaacag acaaaactaa aaactttatt aaaatatctt
    31081 tatttttaaa atgcattaat tcatgtttca aaatccaagt tagttcatct ttactataag
    31141 gatagtctgg taagaatatg taagatttaa ataatcccat acctgctgga cttatcaatt
    31201 catcagaacc tcttaattca attttctttt ttatatttaa ttcttttaac aagtttttgt
    31261 agatacagtt tatatcatta tcttcaatat cataagatac atcaacaact agatttttaa
    31321 atcttgtata ctttataaat gtataaactg caatgactat agttacaaat aaccataaat
    31381 aagctacata cagcataaga ttattatctg tagaaatatc aatttgtgta atattatttc
    31441 ctaatgcatt ttctttgggt tcttttactt catacactat tgtataatta aatagaaaaa
    31501 gtaacattct aaagactatt atcaaccaaa tataataatt gaatctctta ctaaacttct
    31561 taaataaata tcttttcaaa aataataata gacaaatacc aagactacat acaatagttg
    31621 tctttataag attttcaaaa acatatagca tataattatt catcctttaa attatcaaaa
    31681 taactttcta gaaaatctag cttatcttta cctatatttt catcatcatg taatgctgaa
    31741 attaagcttc ttaaagagtc atcatgtata ttacttagga aatcctttgt ctcaaaactt
    31801 aaataatctt tgtgttttac tcttattgtg taatgtgtat atctgtctat tttttgagca
    31861 tctaagaatc ctctttttac cagcctagat aaaagtgtca gtgtggtggt ttgtttccag
    31921 ccatattttt gttccatagc ttcaataaca tcttttgatg tcactgtaac atctactttc
    31981 caaatgaatt tcattacttt tagttctgct tgtggtattt ttcttatcat tatttacacc
    32041 tccctcaaaa ctcctgctac cttaattcta caacatgtga attttttagt caaacacttt
    32101 atgaaaaaaa tgtgaatttt tgtacttttt gttaaatttc taattttttt acaatattaa
    32161 aagttagatt ttaaaatata tctatttaaa tattttactt tttacatatt taattacaat
    32221 agtgtagaat gttatttaca cattaaaact atttaataaa aattcctata ttttcacaca
    32281 aggaatatta taatactttt ttttaaaata aactagagta atatctaata aattttaata
    32341 acattctaat tatgccttta tgctattaaa acatctattt tatactgatt atttacaaat
    32401 atatctaaat taattataaa ttttattgaa taagactttt ataattatac ctttcataaa
    32461 ttataaaaaa gtacttttat aaaaaaatgt gcttttaata tctactaata aagttcttta
    32521 ttttaattaa aacataatta tatttta
//
LOCUS       DAYAKB010000042        31310 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.042, whole genome shotgun sequence.
ACCESSION   DAYAKB010000042 DAYAKB010000000
VERSION     DAYAKB010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31310
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.042"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..747
                     /locus_tag="ACGI3L_002276"
     CDS             <1..747
                     /locus_tag="ACGI3L_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HFG9197978.1"
                     /translation="ILMGLASIYSILNKEDISLTVKGQEQKVSSFKKTVEELLDEQGV
                     KYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFDTKHVNDSNLLKGKSKVY
                     QEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIKYGTKEKVLIASRGANIR
                     GGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTKVYIPKLGMTFVAEDCGG
                     AIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            857..1447
                     /locus_tag="ACGI3L_002277"
     CDS             857..1447
                     /locus_tag="ACGI3L_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFG9197979.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            1513..3210
                     /locus_tag="ACGI3L_002278"
     CDS             1513..3210
                     /locus_tag="ACGI3L_002278"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFG9197980.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            3424..4263
                     /locus_tag="ACGI3L_002279"
     CDS             3424..4263
                     /locus_tag="ACGI3L_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFG9197981.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            4780..6636
                     /locus_tag="ACGI3L_002280"
     CDS             4780..6636
                     /locus_tag="ACGI3L_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9197982.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGTYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    6719..6959
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    7025..7260
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7345..8562
                     /locus_tag="ACGI3L_002281"
     CDS             7345..8562
                     /locus_tag="ACGI3L_002281"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFG9197983.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            8679..9161
                     /gene="cdeM"
                     /locus_tag="ACGI3L_002282"
     CDS             8679..9161
                     /gene="cdeM"
                     /locus_tag="ACGI3L_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HFG9197984.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            9425..10690
                     /gene="hisD"
                     /locus_tag="ACGI3L_002283"
     CDS             9425..10690
                     /gene="hisD"
                     /locus_tag="ACGI3L_002283"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HFG9197985.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(10893..11645)
                     /locus_tag="ACGI3L_002284"
     CDS             complement(10893..11645)
                     /locus_tag="ACGI3L_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9197986.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(11763..12032)
                     /locus_tag="ACGI3L_002285"
     CDS             complement(11763..12032)
                     /locus_tag="ACGI3L_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HFG9197987.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            12507..13601
                     /locus_tag="ACGI3L_002286"
     CDS             12507..13601
                     /locus_tag="ACGI3L_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9197988.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            13603..14553
                     /locus_tag="ACGI3L_002287"
     CDS             13603..14553
                     /locus_tag="ACGI3L_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HFG9197989.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            14546..15730
                     /locus_tag="ACGI3L_002288"
     CDS             14546..15730
                     /locus_tag="ACGI3L_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9197990.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYKKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDAFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            15743..17239
                     /locus_tag="ACGI3L_002289"
     CDS             15743..17239
                     /locus_tag="ACGI3L_002289"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HFG9197991.1"
                     /translation="MSKILEIQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            17262..18212
                     /locus_tag="ACGI3L_002290"
     CDS             17262..18212
                     /locus_tag="ACGI3L_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9197992.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            18233..19195
                     /locus_tag="ACGI3L_002291"
     CDS             18233..19195
                     /locus_tag="ACGI3L_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFG9197993.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            19567..20199
                     /locus_tag="ACGI3L_002292"
     CDS             19567..20199
                     /locus_tag="ACGI3L_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9197994.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            20625..20702
                     /gene="kdpF"
                     /locus_tag="ACGI3L_002293"
     CDS             20625..20702
                     /gene="kdpF"
                     /locus_tag="ACGI3L_002293"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA];
                     GO_process: GO:0043462 - regulation of ATP-dependent
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HFG9197995.1"
                     /translation="MWFLAVVIIMLIIYLVYALINPEKF"
     gene            20749..22425
                     /gene="kdpA"
                     /locus_tag="ACGI3L_002294"
     CDS             20749..22425
                     /gene="kdpA"
                     /locus_tag="ACGI3L_002294"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HFG9197996.1"
                     /translation="MVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFI
                     YKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGLSF
                     NTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKKKT
                     LGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVA
                     ALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKK
                     QGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSSLF
                     TTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLC
                     GLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHG
                     LSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGVVMFFGRYVSIIVLLAISSLLASK
                     KAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            22450..24507
                     /gene="kdpB"
                     /locus_tag="ACGI3L_002295"
     CDS             22450..24507
                     /gene="kdpB"
                     /locus_tag="ACGI3L_002295"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HFG9197997.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            24526..25152
                     /locus_tag="ACGI3L_002296"
     CDS             24526..25152
                     /locus_tag="ACGI3L_002296"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HFG9197998.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            25389..26297
                     /gene="cysK"
                     /locus_tag="ACGI3L_002297"
     CDS             25389..26297
                     /gene="cysK"
                     /locus_tag="ACGI3L_002297"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFG9197999.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            26324..26914
                     /gene="epsC"
                     /locus_tag="ACGI3L_002298"
     CDS             26324..26914
                     /gene="epsC"
                     /locus_tag="ACGI3L_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFG9198000.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            27074..27262
                     /locus_tag="ACGI3L_002299"
     CDS             27074..27262
                     /locus_tag="ACGI3L_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFG9198001.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(27316..28185)
                     /locus_tag="ACGI3L_002300"
     CDS             complement(27316..28185)
                     /locus_tag="ACGI3L_002300"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HFG9198002.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(28382..29626)
                     /locus_tag="ACGI3L_002301"
     CDS             complement(28382..29626)
                     /locus_tag="ACGI3L_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198003.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDGLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            29917..30228
                     /locus_tag="ACGI3L_002302"
     CDS             29917..30228
                     /locus_tag="ACGI3L_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFG9198004.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      30321..30413
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            30513..31307
                     /gene="thiD"
                     /locus_tag="ACGI3L_002303"
     CDS             30513..31307
                     /gene="thiD"
                     /locus_tag="ACGI3L_002303"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFG9198005.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
BASE COUNT        12192 a         3293 c         5587 g        10238 t
ORIGIN      
        1 attttaatgg gtttggcaag tatatattct atattaaata aagaagacat aagtttaacc
       61 gttaaaggtc aagagcaaaa agtatcttcc tttaagaaaa cagttgagga acttttggat
      121 gaacagggtg taaagtataa ttctgaagat aagattaatc caagtttaga tacagagtta
      181 aaagatgata tgaaaataaa agttgttaag gtaactaaaa gtaaaaaaga agagattgaa
      241 aaaattccat ttgatacaaa gcatgtaaat gatagtaatt tgttaaaagg aaaatctaaa
      301 gtttatcaag aaggtcaaga aggagaaaaa aaactagtct ataatttaac ttaccatgat
      361 ggcaagttag tcaaaaaagt cttatcaaaa gaagtaatat ctaaggagcc aactacaaaa
      421 attataaaat atggaactaa agaaaaagta ctaatagcat caagaggagc aaatataaga
      481 ggaggcaaac atatgaaagt ggttgccact gcatatgcag gagatacaat aacatctact
      541 ggtacaactc caagatgggg tgttattgca gttgacccac gtgtaatacc atatggaaca
      601 aaagtatata tacctaaact gggtatgact tttgtagcag aagattgtgg aggtgcaatt
      661 aaaggtaata gaatagacat ttttatgaac agtgaaggaa aagcttcaaa ttggggaagg
      721 aaaagtatag atatatatct acattaaatt agtgaataga ataactttac ttgaaggaca
      781 aaaaagtata aaatatgaat taactaaact gttagattat tcttaaaaca taaaaatata
      841 tctaaggggg gataagatga aaatagtctg cttaggagac agtttaacgt atggatttgg
      901 agtatcacga agtaattcat ggacaaacat tgtaaataaa gagactcgat tagaaatagt
      961 aaataagggt ataaatggtg atacaacaag tggtatgtta gctaggttta atgaagatgt
     1021 tgtaaaaaac tctcctgata tagtttttat aatgggtggc accaatgatt ttattgctgg
     1081 tgcgggaaat gaaattatta attctaatat aatggctatg gtgcatcagt catattcaaa
     1141 aaatattata cctataatag gtataccatt aaaaccagat attccaaatg ttagggaaga
     1201 ttggagttgt tttactgatt ttaatatagt atctcaaaac ttagaatcat atagttattg
     1261 gataaaaaaa ttttgtatga catttaatac taatttcgta gatttttatt cagaatataa
     1321 taaaaatatg gaactagaag gatataaaaa attatatttt gatgggttac atccaaccaa
     1381 agagggtcat agaataatgg cagacatttt tattaattca attaataagt atatagaaga
     1441 gttatagatt acattaaaat gcttgtttat gcgtcagttg caataaatac atacagtaga
     1501 gaggggttta ttatggatta tactaaaact tatgaagagt ggataaaggg ttcatatttt
     1561 gatgaagata caaagctaga gttggagaat ataaaaaata atgaaaaaga aatagaggat
     1621 agattctata aggatttaga atttgggact gcgggtctta gaggaataat tgaagcagga
     1681 acgaatagaa taaataagta cacagttaga agagctactt ttggattggc aaactatata
     1741 ttagaaaaca caacaaaaga agaaacaagt agaggagtag taatagctca tgataataga
     1801 cacaagtcta gacaattctg tatagaatct gcaaatactt tggcagcatg tggtataaaa
     1861 gcatatatat ttgatagttt gagaactact ccagaattat cttttgctgt tagaagctta
     1921 aatgcaatcg ctggtatagt cataacagca agccataatc ctccagaata taatggatat
     1981 aaggtatact gggaagatgg agcacaagtt atgccagaga ttgcaaatgc aataacagag
     2041 aaagtaaata gtatacatga ttatagtaca ataccaacct taacggaagc taataaaaat
     2101 ttggtagttt tgttggacga atcacaagat actaaattta tagaagcagt aaaaagccaa
     2161 attataagaa aagatttagt taaaaatgta ggtaaaagct ttaagatagt ttatacacct
     2221 ctttgtggaa cagggaatgt tccaataaga agagcattga aagaagttgg ttttgaaaat
     2281 ataattgtag ttccagaaga agaaaatcca gacccaaatt ttgcagggct tgattatcca
     2341 aatccagaag agaaaaaagc tttaaataga ggtatattac tcgcaaaaga aaaaggagca
     2401 gaccttgtaa tagcaactga cccagattgt gatagagtag gtgtagcagt aaaaactact
     2461 acaggtgagt atgctttact tacaggaaat caaattggtg gtatgctgac acattatata
     2521 atagaaggat taaaagaaaa taataaatta aaagaaaatc ctacaataat aaaaaccata
     2581 gttacatcag aatttggagc agatatagct aaagcaaata atgttgatgt attaaatgtt
     2641 cttacaggtt ttaaatttat tggtgaaaaa ataaaattat ttgaacaaaa taaaaataga
     2701 agttatgtat ttggatatga agaaagttat ggttacttag ttgggactca tgctagagat
     2761 aaagatggtg tagtttcttc attgttaata tctgaaatgg cagcatttta ctattcaaaa
     2821 ggtatgagtt tatatgatgg cttaatagaa ctttataaaa agtatggatt tttcaaagaa
     2881 cagactatat ctttgacttt aaaaggtata gaaggtgtag aaaagataaa agaaataata
     2941 tcttatttta gagaaaatca aattgattat ataaatagta ttaaagtagt tgataaaaaa
     3001 gattataaaa atggtataga taatcttcct aaatctgatg ttttaaaata ctttttggaa
     3061 gatgaatctt gggtagctat aagaccatct ggaacagaac caaaacttaa attttacata
     3121 gctgtaaaag gagctagtga tattgaagca gataaaaaga ttcaaggttt gaaaaagtat
     3181 atagatgaca tggtcgaaaa attaaaataa aatattatta ttttataaga taattttgta
     3241 ataatattta tttagctgaa aattataatt tactttcatt gagtagaata tggaaatgtt
     3301 agtagaattg ttattttcag cttttatttg tgttattttt acttaaataa ttatattata
     3361 gaatgaatct gagtataatt aatattgtat aatgaaatta atttgataga aaaggggata
     3421 tttatgtttg gtatagataa gaaattgatt gaatatataa ttgcaaaatc caattacagt
     3481 gaattaagtt caaagtcagc agaagtatct ttcttcttaa tgttgtccat atttcctttt
     3541 ttaatattta caataagttc tatagcttat ataccgattc ttcatttaaa taagtatata
     3601 gctttgttta gaaatatgat gccagaaggt gcttttgctg tgttatcttc aatcatagtt
     3661 tctgcaatag acaatagaaa cctgaaattt ttagcagtca gttttgtact tactatgtgg
     3721 acattttcaa gagcagtaaa agctcttatt aaaggaatga atagagccta taaagttaaa
     3781 gaaactaggt ctttttttaa aattttatct atatcatttt tatttacaat aatgcttttg
     3841 gtccttattt ttttatctat gatattttta gtttatgggg aaaaaatagg ttattttatt
     3901 tttaatcttg taggattgga tgagatattt ataaaaatat gggatattct aagatacact
     3961 gtaggtataa taacaataat agtgatattt acacttttat ataaatacac tccaaataaa
     4021 aagttaacta ttaaagaatc tgcgccaggt gctatttttg ctacttttgc ttggttttta
     4081 gtatcatttt tatattctta ttatacaaat tactatgcta actatgaagt aatctatgga
     4141 agtatagctg aaataattgt acttatgacc tggatgtatt ttagtagttg gtctatcgtt
     4201 attggctatg aggtaaattc aagattgtat tttagaaaga taagacatga aatgttaaag
     4261 taaagtattt aaaataaaag agagtattta gtattataaa tgtaattgaa ttaataaaga
     4321 aatattgaca tttaagttaa aaagtctaga atttttctgg gcttttttta tttttagtat
     4381 aacttgacaa attttattta atgggatagt tttaatttat aatcatcttt aaaaagatga
     4441 ctattgataa gtaagagata aaattggtaa gtatcaaaaa atatactaaa taaaaattat
     4501 agtcctaatg agttaatttc tgtattttca aataatgcag tatttagtca tgtgttttta
     4561 tatgcgcctg tatttctaat taccaatata ttagaataag ctactgtaat tagatttaga
     4621 aaaaagcgac ataaataatt ataaacaaat aataaattac ataaaattaa atttattcac
     4681 aagtatatct tataaaatat gttataatta atagaaaatt gtcatataat taattaagta
     4741 gtattattat aaataacatt gaaaggtagt ggttagaata tggataccca taataaatat
     4801 gtaaatttta taaaaaatat acctgtacct tttttatatt gtagaattgt aaagagacaa
     4861 gaagatatag aatatcgagt agaatatata agtaagggta tgggcaaagt attacaatta
     4921 gaagaaggta tttgtgataa aaatatacta gatgtattgc ctgtatttaa gtctaaaaaa
     4981 tatttcaaag agttgttctc aaatgaagtg gattgtataa aaaggtacat tccgacactt
     5041 aaaaattgga taaatataaa aaaacagata ataggggatt catacataat tttgtatttt
     5101 ggtaaaattg tatttgatta tagacagata atcgattcct ttgataaaaa ggaaaaagta
     5161 gcttatatta aagacgaaga aggcacatat atagattgca gtgaaaattt aataccaata
     5221 ttaaataaca acattaaaac aacgaaagat atctttggta aaaatgatat agaagtatgg
     5281 ggagagaata caggaaaatt atttagagat gattatagag aaggagtatc tagtaaaaaa
     5341 agatttttac aaaatctttt tgaatatgaa gaaacatttt ttatggttga aaaatatttt
     5401 ttgtatgatg aagacgaact tttaggtact atagggatag tagacaatat aatatatagt
     5461 ggttacagta atagaaatta taactcaaaa gatttaatga agatgataga acactcaatt
     5521 ccagagaata tgttttataa agatgtgtat ggaaattata ttggatttaa ttcaggtttt
     5581 ttgaatttag cttgtatgaa taaagaagaa ttattaggga agaatagtta taaaatatca
     5641 gaagaagaag ctttaataga taagatattt gaaagtgata agggtgtagt tgaaaataaa
     5701 aaagtagtta catttgagtt aaatataagt atgaatgatg aaaacaagtg tattgagatt
     5761 acaaaaaggc cgttttttga tagctatgga agtgttattg gaataattgg aacagcaagg
     5821 gatataagta gaagaaaaag attagaagag gaaatggata aaactaggat ggaatttttt
     5881 gcaaatttat cccatgaact tagaacgcct ataaacttaa tatcatcttc attacaagtg
     5941 atagaaaaaa aagaagcaga tttaatagaa tcaaatgata ctttaaaaag aaatttaggt
     6001 ataataaaac aaaatggaaa tagaatatta agattagtaa ataatgttat agattttaca
     6061 aaaatgcaat caggatattt agattttaaa ccagaagaat ctgatataat tgcatttata
     6121 gaggagatat gtatgtctgt agctgatttt gcaagccaaa ataatataca acttacattt
     6181 gatacagaaa tagaagaatt ttcaatgtta tttgattcag aaaaattgga aagaataata
     6241 ttaaatttac tttctaatgg aattaagtac aataagaaag atggaaaaat aaatatattt
     6301 ttatatgtga aagataatgt atttaatatg aaaatatctg atagtggaat aggaatacca
     6361 aaagaaaaaa tagataaaat atttaatagg tttgaacaga ttgacaatga actttcttac
     6421 agagttaaag gaagtggtat tggactttca ttagtgaaat ctttggttga gttgcatgag
     6481 ggaagtatat ctttaaaaag tcaacttggt attggaagtg aatttatagt ttcattgcct
     6541 gttagaagta aaaataatat tgaaaaatat aatcataaaa gagaaatcag caatgaatta
     6601 agtaaaaaat tagaaataga gttctcggat ttataagttt aaatataaaa aataaaattt
     6661 taaaaaagta ttgacaattg atttagaagg gtttaaaata aattacaaca taataaataa
     6721 aaaggcgatg aataggaaga gtaaatctaa ttcgattacc agagagaaga gtccgttggc
     6781 tggaagactt tttaaattag agggattgaa aactacctag gagctacttt ctgaagtcat
     6841 ctgcattagt agattttagt aagaatagtc gttagctgcg ttaaagtgta aagtgagttt
     6901 tcatgacata tgaaaactaa attaggtgga accgcgggaa taatactctc gtccttatgt
     6961 tataaggatg agagtttttt gttatttaaa aatataaaca gtaatcataa taattataga
     7021 aaatataaaa gcaatgaata ggaagagtaa atttaattcg actatcagag aggaaagttc
     7081 acaggctgaa agactttcta agtttgagaa attgaaaact acctaggagc tgtggtctga
     7141 agttacttta aaaagtttta gtaagactaa ccgttaactg cgttaaagtg taaagtggat
     7201 tttatcaata aatgataaaa tcaaattggg tggaaccgcg agtatagact cgtcccttta
     7261 tatagggatg agtctatttt tattgcaata aaagattgaa aataaaaaaa aatcggaaaa
     7321 ttataaattt aggaggaaaa taaaatggag aataaagtga aaattggagt actaggatat
     7381 ggagttgtag gaagtggact tatagatata atagataata ataaagaaaa aagaaatata
     7441 gaaatagttg gaattttagt taataatttg gaaaaacata aggataaaaa atattctaat
     7501 ataataacta ataatataga tgatatattt aataaagata tagatatact tgttgaagtc
     7561 atgggtggtt tagaaccatc attatcttat ataaaaaaag cattaaacaa taaaattcat
     7621 gttgttacag caaataaaga tttgttagct gaatgtggag atgagcttgc aaaattagca
     7681 agtgaaaata aagtaagtat taaatttgaa gcttcagttg caggaggtat accagtatta
     7741 aaaccaataa tagaatcact agaaggaaat aatatagata gtataaatgc aattttaaat
     7801 ggaactacta attttatatt atctaaaatg tatgatgaga atctatctta tgatatggca
     7861 ttaagacaag cacaagaatt aggttttgct gaagcaaatc cagagtcaga tgtattaggg
     7921 tatgatgctg ctagaaaact atcaatatta tcaactctag cttatgacaa tagagtatat
     7981 tggaaagatg tgtatttaga aggaattaca gatatagatg aaaaagatat tgaatatgca
     8041 aaaaaattaa attgtaaaat aaaattgatt ggtcaaagta agtatgaaaa tgataaagta
     8101 agtgcttttg ttagacctgt tttagtagaa aaagataata tccttgctag aatagacaat
     8161 gagttcaatg ctgtcatagt gaatggagat tcagtaggag aagtttcttt tgtaggtaaa
     8221 ggagctggaa gtttagcaac aggaagtgcg gtttattcag atgttataga tataatagat
     8281 aatagagttt caagtataga ttcttttact aaagataaaa tacaagttaa taaaatagtt
     8341 agagaaaagt gtggagcact tcttagattt aaaaaatgta ataaagatga aattctaaat
     8401 atagttgaga attgtttagt aaaattcgat attttaaatg atgatgatga acttgctatt
     8461 atggtttatg ctgattctga atatgaaata aacaacagtt tatgtctaat aaaagataaa
     8521 ggatactgcg aaaaaatgaa taaaatgttg aaaataagtt aaaaaagaaa aaatataagt
     8581 ttatatgtaa catattttga cgattttaat actatatagt atgagatgaa acaaaacatc
     8641 tcataaaaaa attaaaatta aagggagaga tatgttatat ggaaaataaa aaatgttatt
     8701 cagaagattg gtatgaaaga ggagaatcta cagctaaatg gttccaaaat gatagagaag
     8761 aatatgaaag agaagcatat gatgaagata gagaaagaag aggttcaaac tgtggatgtt
     8821 cagattcagg agaaaataga cctagaaact gtgaaagatt tagaagagaa gctgagataa
     8881 gagaaagaga agcaagagaa gcattctgtg aatcttcaga gaaaaagaaa gaggcattag
     8941 catatgaatg tgaagctaga aaattatggg aagaagcaga aaaatactgg gatgaatatt
     9001 caaaatacaa ctataaagga atcgaatatt tagcagaagc tgctagatta tttgatgaag
     9061 gtatggaatg tgaagctaga agaaatggaa ataatggagg aaacaataat aattgttgcc
     9121 ataaatgcca taaatgtaat tgtaactgct gtagaaaata aaaaaattaa ttgacaaatc
     9181 aatagttaaa atatatcata ttatgtataa taaagagaaa attcagaaaa aaataatgat
     9241 tagaagaaat ataagtatat ttattagaca aatagtgctc agttagtgag gtgagtacaa
     9301 tatgattaaa ctcccatcct ctagcttttg atagagggtg ggagttttta tttatttata
     9361 tatcttaaat gaggataata ttgtaaaata aatgagtatg agattgtaaa attaggaggt
     9421 aaaaatgaaa agtattaaaa catcaagtat gaaagaaaag gtagatgaaa agatattaag
     9481 agagcaagta agttctataa tagaagatat aagaaataat aaggatgttg cacttaaaaa
     9541 atataatgag aagtttgata gaaatacaag agatgaattt agaattacta aggaagaaat
     9601 aaaggaagct tataagcatg tagatgacga atttataaat aacttaaaga ttgctgccaa
     9661 aaatataaga gaatttgcta aagctcaaaa actaagtttt gaaaaccctt ttgaaaaaga
     9721 aatttatcca ggtgtaatct taggtcaaac taatattcca atagagtcat gtcttgcata
     9781 tgttccagga ggtcagtatc cattgttttc aacagctctt atgcttataa tacctgcaaa
     9841 agtagcagga gtaaaaagaa tagtggcatg ttcaccaact atgaaaaata ctgaaaagat
     9901 aaatcctaag acattggtag ctatggatat agcaggtgct gatgaaatat atgcaactgg
     9961 aggagttcaa gctatagcag catttacata tggaacagaa aagattaatc cagttgacat
    10021 aattgtagga ccaggaaata agtttgtaac tgaagctaaa agacaatgtt atggacaagt
    10081 agggattgat tttgtcgctg ggccaagtga agttcttata atagcggatg aaacttcaaa
    10141 tccagtttat attgcagctg atttattagc acaatgtgag catgatttaa atgcaagagg
    10201 aatattattg acaaatagct tggaagtagc acaaaaagtt gaaaaaaata tagaaagtat
    10261 gctaaaagat ttgccaacaa aggacatagc atatagttca tgggaaaata atggagagat
    10321 aatattggtt gatgatatgg aagaagccat taaaataagt aatttttatg caccagaaca
    10381 tttagaagtt gcagtaaatg agtataatga tatttgtgat agattaacta actatggttc
    10441 tttatttatt ggaaatcttt ctgctgaggt gtttggtgac tatgtttcag gtaccaatca
    10501 tacattacca acacttaaag catcaagata tactggtggt gtttgggttg gaacttttat
    10561 caaaacttgt acaaagcaga tatttaatga aaaagctata caatcattag cacctgtagc
    10621 tgaaaagctg gcaaaagaag agggattata tgcacatgca aaggctgctg aggttaggtt
    10681 taaaaagtag taaaaaattt tattttggca gtcgagactt agtattagac tgagataagg
    10741 aaaacgctga gaacctgaat aaatactata ttttgtgggt ctcggcgctt cttttatatc
    10801 tgtatataat agaataatac tatctgtgtg tttaaatact aacttaatat ttcttttcta
    10861 aataatgttt atgaaatagt taatattttt agttaatact tgaaaaaaac ttttgctaac
    10921 tgtgcaaatt catctgcatt tgtcaatata gcagggtgtc ctccctgact aaaaatgtaa
    10981 atacttgctt ttgaaataaa agttgccatt tgcttgtact cttcttcaag attatgacga
    11041 cacatttcgt cttccttact tcctgtaaat aaaattggca tttctaattt acacaattct
    11101 ttatgaaaca aagggcgttt ctcgtttgca cattgcaata gagcttttgt atcaagatta
    11161 acaacattct cccaatcttt tccatgacac cattcataga attttcgtgc ttgaatatct
    11221 tgctttgatt tttcccttcc agtgattaga ttatctatga agttatcatt aagagtacgt
    11281 ccatcaaagc tatctgctat aattgcttca actaaatcgg gacgttctaa tccagtatta
    11341 acagctgccc atgctcctcc acttgttcca attaagccaa ctttaccaca attcaaatgt
    11401 tcaatcagtg ctattgtctg taaggcttca tcatgccata tgtcaggaga aaattgagaa
    11461 actctatccg actgtccatt acctaaaaaa tcaattaaga tacatctaaa attttctgca
    11521 tataatggca caagtgcttt aaacatatta gaagaaccag tattaccatg caggaaaatt
    11581 atcggtttac cttgtccata ttctttataa aaacaagaat taccttgata ctgaaaatat
    11641 gacatatatt ttcctccttt ttatttgtta agttaattat aacaatatag gtatgaatga
    11701 aaaacctcat gttctttctt agaataaaaa tgtgccacgc ataaaacgtg acacatttct
    11761 aattataaat tttgctgttt aagtattctt tgtatgcttt tctctgtcaa aaagtatttc
    11821 tctgataact gcttgatact cattccattt tggaaattta tacagatttg agaattacga
    11881 gaagctaaga cttgtttggt gtttgtgttt tcaccccaat gctttttgtg ctcttgcttt
    11941 ttgggaatat aaatcacttt accatctata tattcttgca cttgctcaat cagttcttta
    12001 ggcagtaagt caatcgaatt ttgatagctc attttgcacc tcctaaataa ttattcttta
    12061 ggattagcaa aggctactgc cactcacaat taaaaataaa attttttatt atgtacaata
    12121 gcctttgcta tgcacaagtt ccaattccca taaactaaat actcctttct ggtttgaaaa
    12181 attcatctga acattgattt cgcttttaag atagagttca atgacaaatt tacattttta
    12241 ttatatatat tcagatagat aattgcaact gtctttgtat gaggatattt tattatagtc
    12301 aatactataa tatgtattta tatcatcaaa ctaatatgaa cagttgaaag gaatatgaac
    12361 aataaaactt agtcaggaag aataattatg aagcagacaa tagagaaatt tgattttaaa
    12421 gttttattga aaatttattg acaaatttaa cttgtaaata ttatactaaa cttaataaat
    12481 aaagtttata aagtaaggtg ttgtctatga aaaatatagt tggaaaaccg caaacgataa
    12541 aaaaagtaaa tgaagattta ataaaaaaca ttataaaaaa tgaaggtcct ataacaaaac
    12601 cagaaatttc aagcattact gaattgagtt tagctacagt taataagatt gtagagcaat
    12661 tagctttgaa aaatgaagtt aaagtaagtg gactaagtga atctactgga ggaagaagag
    12721 ctcaattatt tgaaataaat gcaaacttag aacacataat agctttatat tattatagaa
    12781 attgttgtat aggggtagtt gccaatttat taggtgaaat aatttatcaa gaagaattta
    12841 atataagaat ggatacgtat gaaaacgtta accaagatac tttttttgtt atagatactc
    12901 taataaaaaa ggaaaaagga aacaatataa gggctattgg aattggtgtc ccaggagttg
    12961 taaaaaaagg tgtagttaaa aatataccaa ctataaaaag ttgggaaggt ataaatttag
    13021 aaaatttaat aaagagtaaa tacaatacta aagtgtttat agaaaatgat acaaatatta
    13081 ctactattgg gatttatcaa aaacagtata aagacaaata taaaaatatg gctcttatgt
    13141 atttagaaga tggtattggt tcaggtatag ttataaatgg tgaattgtat ttaggttcta
    13201 caaattttgc tggagaatta agttatctaa atatagaatt tggtaagtat aactctaaca
    13261 acttaaatct tgaagattat attatgagtt taagaaaaag atatttagaa agtaaagata
    13321 ataaatttaa gaaagaaatt ttatctataa tatcaaactt tataaggact cttgtatgtg
    13381 tcctaaatcc acaagctatg attatacagt gtagtatatt aaccaagagt gacatggagt
    13441 ttatagaaaa agatgtaagc aataatgttg gagaagaaaa ttttcctaaa ttaataaaag
    13501 tagactcatt gagagaagga agtataaatg gagtaattag tatgtgttta aaagaaactg
    13561 actatcaata ttccttatct aataaaaaag gaggatatta atgtgaaata tttggtttca
    13621 atagatggag ggggaacaaa aactaaattt tgtgtaagtg acttagatgg aaacatactt
    13681 aaagaacata ccactggttc aactaattat aagtcagttg gaattaaaaa aacatatgaa
    13741 aatattaata atggatttaa aaaaatatta aaagatttat atatcgatta tgacgatatt
    13801 gagtacactg tatttggtat atctggttgt gattctccta atgattataa gattataatg
    13861 gatgaaatat taaaaattgg gattaacaaa gaaaaaatat atctggcaaa tgatgcagtt
    13921 ttagcttttt atgcacaagc tgattcccct ggcttagtaa ttgtggctgg gacaggttca
    13981 attatactgg gaattaaaga agatggagaa atatatagag ttggtggatg ggggtataat
    14041 tttagtgatt tgggttctgg atatgatata gggagaaaat tattaaagaa agtattgctt
    14101 tattgtgatg aatgtcatga gtatagtgat ttatttagtt gtgtcttgga cttctttgga
    14161 gcaaatagtt ttgaacaact tgcatatatg attactgata taaatgataa tgttgaaata
    14221 gcaaacttag cttcattagt gattgattgt gccgaacaag gtgataaatt ggctattgaa
    14281 atattaagag aatcatcaac tgaactatct aaattagctc aagtaatatt gagaaaaata
    14341 tctaatccaa tgaaaatgga taaaagcgaa ataaatatag ttttgtctgg tggtacatta
    14401 aataaaactg tatatgctca aatgttaatg aataatttaa aaacagaaaa tacagataaa
    14461 aatttaaaat ttatatctca agaaaatcag ccagtatatg gggggataag acttgctatg
    14521 gcattagcta ataggagggt caagcatgga tagaaaaaag gtaatagtac aaatttttac
    14581 tggaggtttt aaggctaaag aaataaagtt taatgatata aaatgtaaac tactagaatt
    14641 attggactgt attgatatag aaaaggttat catgggatgg agtgtagatg aagaattata
    14701 tgtagaaact aaaaaactat taaataaata taatgttgaa ctatatcttt ggttgccatg
    14761 tttttctgaa ataggattac ttgaaaaaag taatttacta attgattata tggggaagga
    14821 agtcaagggc tatgctttac aagaggatga aaattttgag ttttattgcc caaataataa
    14881 ggaaaatata aaaaatataa agaaaatata tagtacttat tttagtgata ttaaatttga
    14941 tggaattttt ttagataaaa taaggtatgg ttctttttcg aataaactaa atggtgtttt
    15001 taattgtttt tgtaaagatt gtttaaatat atataaaaaa aataatattg ataaagagtc
    15061 gttaatgaga gaaatgaata atgtgtctaa gggagttata gataatgaag atactccatt
    15121 tggtataaca gaatacatta atggaaaata caaatttaaa aataaaatat gggaagattt
    15181 ttttgaaaca aaaaatcaaa atatatacaa ggcattatta gagataagta gttattttaa
    15241 aagtaaggga ttgaaaatag gtatagatgc tttttctcct tttatttctt actttacagg
    15301 tcaagattta gaaaaattac aagaagtagc agattttata aaaccaatga tgtatagaac
    15361 tacaaaagct ccagctggtt taccatttga atttgaaagg tttattgatg aatccataca
    15421 taagaataaa gagattggaa aaagaaattt cttagatatt ttaggaatta aggagtatga
    15481 aggagatgta tatcctatag aatttgtact agaggaaatc gattttatga caagaaatct
    15541 taataaagat atatatgtag gagttgaaat aaataaaaag gaaattatat ctcctgttac
    15601 acctaagtac ataagtgaaa atatttcaaa tataaataag acaacagtaa aaggatatgt
    15661 tttatcttgg gatttgttgt cagcaccaaa agaaaatatt gatgaaatta taaaatggtt
    15721 tcggaattag tgaggtgata aagtgagtaa gatattggaa atacaacaaa tatataaaag
    15781 ttttggaaag gtagatgttt taaaagggat aaattttgag ttagaaaagg gagaagtaag
    15841 agctcttttg ggagctaatg gagcaggaaa atctacactt attaaaattt taggaggagt
    15901 tcattctcaa actaaaggta aagtaatttt gactggtaat gaaataatgt ttaaaaatcc
    15961 acatcattct aaagaaaatg gtattagtat aatttatcaa gaattaagct tgataccaac
    16021 gcttacagta cttgaaaata tttttcttgg tagagaaatt ttaaaaggaa gtgtgttttt
    16081 aaacaagaaa gacatgcttg aggaatatat gaaaatttgt gaggattttg attttaatat
    16141 agacccacat atagtagttt ctaatttaag tgtagcaaac caacaaatgg ttgagataat
    16201 gaaagctgtt tcatgtaatt ctgaaattat cataatggat gaacctacaa catcacttac
    16261 taataatgaa aaagatgggc tatttaaaat aataagtaga ctaaagtcta aaggtaaaac
    16321 aatagtctat atttctcaca tattagagga agtttttaaa gtatgtgata gtgcaagtat
    16381 aatgaaaaat ggaattatga ttggaactta tgatgtagag gatttaacta aattaaagat
    16441 aactcaactt atgacaggaa atgataatca caaacttatt gagaagaagg attatacatt
    16501 tgcaaaatat gaagagccac cagtactaga agtaaagaat ataagctggt ctaacaaaat
    16561 aaaaaatgtt tcatttaaag tttatagagg cgaagttgta ggtcttgcag gtcttgtagg
    16621 ttcaagaaga actgaaatta taaatttgat atttggtata gataataaag atagtggaga
    16681 tatttttatc aatggtaaaa aagtagacat aacttctcct aaggttgcta taaaaaacaa
    16741 aataggattg attcctgaag atagaaaaaa tctaggatta attttagaac aagctatata
    16801 cacaaactca tcatcagtac aaattgataa attcaagaaa tttttgttta tagatagaaa
    16861 taaagaaatt gagttttcta aaaaaggtgt taaggaatta ggaataaaag ttagtgatgt
    16921 aaagcaagaa gtaaaagagc ttagtggtgg aaatcaacaa aaagtagtag tttctaagtg
    16981 gttagagaaa gatttagatt taataatata tgatgagccg acaaagggaa tagatattgc
    17041 tgcaaaagaa gatattttca atacaatcaa agaattttca agtaaaggaa taggagtaat
    17101 atttatatct tctgatttag aagaagtaat aagagtaagt gatagaattt tagtaactag
    17161 agaaggttct attgtagatg atttaaaaaa tgagaatata caggttcaag atataatgaa
    17221 cagtatattt aatgtataaa aaatgaaaat ggaggactga gatgaagaaa gcttttgaga
    17281 agttaaattt aagagattat ggagtattat taggtttttt agctttatgt atagctataa
    17341 gtattgcaac tccatcattt ttaggtaaac aaaatatact taatctttta cgacaatctt
    17401 ctataattgg aataatttca gcaggtatga cttttgttat aatatctgga aactttgata
    17461 tatcagttgg agcagtagca gctcttgcag gtgctataac aatgaaattt gcgactggtg
    17521 gaactaattt gtttgcatcc atgttcttag gtgtagcgat ttgtgcagta ataggattaa
    17581 tcaatggtat agtagttgca aagataaatg taccatcatt aatagccact atggctatgg
    17641 tcactattgt aagaggattg ctgttgatgc ttacaggagg atatccaatt actgaaaata
    17701 taccaatact tgattacatt ggaaatggat atttgtttaa tataccaata ccagtagtaa
    17761 ttttctttat agtggtgtta gcttcgttta ttgtacttaa taaaactaag tttggtagat
    17821 atgtttattc tgtaggaggg aatcaagaag caagtaaact taatggtata aatgtagatt
    17881 ctcacaaagt gaaagtgttt attattaatg ctgtacttgc aggaatagct ggaatcgtac
    17941 taacaggaag acttgggact gcaactgcga ttgcaggtga aggatatgat atggatgcaa
    18001 ttgcatctgt agtaatagga ggtacatcag tggcaggagg ttctggttct gtacttaaaa
    18061 ctgttatagg agtattactt atgagtgtta taaacaacag ttttaatctt cttggaatag
    18121 atgtatattt ccagtacata tttaaaggat taataatttt agcagcagtt ggatttgatt
    18181 cttatagcaa gaaaaaactt gcttcaagat aaaaaataag ggggattttt ttatgaaaaa
    18241 attaatgaaa catttagcat tgttgctatc acttgttatg atatttggtt tagttggttg
    18301 ttcaaatggt ggtgacaaag aaaaaaatgg agaaaagaaa atagcagtat tactaccagg
    18361 ttcaacaggt tactttgtag caactaaaca aggtatagat gcaaaatcta aagaattagg
    18421 tgtaagcgtt gaatatgcag atgctcaatg ggatgctagt aaacaattat cacaagctga
    18481 agattttatg gctaaagggg tagacatgat tgcattatgt ggagttgatt ctgctgtaag
    18541 tgagagaata gttaaagctg ctaatgattc agacgttcct atagtagcat ttacaaattc
    18601 tataggaagt aacccaactg gagaatttaa aggtttagtt acatatatag gacaaaatga
    18661 ggaagaaaca ggagcattaa ctggaaaaat tgctaaaaac ttattaggag aaactggtgg
    18721 gaaagctgta ttaatagaag gagtaccagg aactactcca caagtattaa gaaaaaaagg
    18781 tcttgaaaaa gaattaaaag atagtaatat agaaatagtt tataatcaaa cttcaaattg
    18841 ggagaaagag caagctttaa aagtaacaga agatttaatt caaaagaaaa ctgattttaa
    18901 tgttataata tgtcaagatg ataattctgc tacaggtgca ggtcaagctt taaaagatgc
    18961 tggtcttaag gataaagtta aagtcatagg tttgggtgga agtaaagatg gattaaaagc
    19021 tataactgat gggttaatag atggtacaac ttatatgtct gctgtagaag aaggtggatt
    19081 agtcatagaa aaggcatcta aattccttaa aggtgaaaaa atagaacctg ttacacaaat
    19141 taaacaagtt gaagttaaca aagataatat ttcagagttc aagggtgaat ggtaaattgt
    19201 catagataat aaataagatt tttagagtta ctttagaaac tatataaagt aactcttttt
    19261 ttaatttaat ttagtgataa attattgaat agtatttcta aacaaataaa aaattaatat
    19321 aaacaaagac ttaattatac taaattataa gtaaaactaa tataaactta tggaaaaaag
    19381 gaaaacgtct aaagtattgg aattactata gtgtaggtgt agtattaaaa aaacataaaa
    19441 aaacataaaa aaattgttga aaaaaatata gaaattttgt ataattaaag atttgaaaag
    19501 tgcggtatac aaagccaatt cttttgtata taatatatat aaattcagaa aaaggaaggg
    19561 atatgtatgg ccaggcggtt atttttagaa aggattggac ttatattttt aggttcagca
    19621 atattagcat ttggagttta taatttttat tatttaaaca acataacaga aggtggagtg
    19681 ttaggtattt tactactgtt aaaaaattta ttcaatatac aaccagcaat agcaaatgtt
    19741 gtaatagatg gtttactact tttagtagga tataaatttt tcggtaaaaa attccttata
    19801 tattcaatag tagcttctat aactttttca gtgttatatg acttatttga agctatagga
    19861 cctctagtac cacaatcaca aaatatgctt ttatcaacta ttttggcagg tgtaactgtt
    19921 ggaactggtg taggtatagt agtaaaagca ggttgtgcat caggaggaga cgatgcttta
    19981 gcattagtaa tttctaagac tacatctttg aacatagggc aagtttattt agcaacagat
    20041 gttattgtat tgttgttatc attattttat ctatcagcgt ttgatatctt ttattctttg
    20101 attgctgtta caattagtgg caaggtaatt gattttattt attatcatgg taaaagtttg
    20161 gatatggata taagtaatga tatagttcca gaatgttaat ataaattaaa taactttaga
    20221 ttttattagg ggtggcagat ttgccacctt ttttgtgtct aaatctttat agaaagtata
    20281 atcccatcta ggtttttgca aatctcaaat atagaattat gttggaatga ctgggaatac
    20341 gattgctaga tgtgcatttt aaaaacccaa ttttatattt atgaaatact aatcattaat
    20401 ggatgtttct taatcctatc tttataccta aaatgataag ataaatgaag tagcaataca
    20461 aaactaaaat ttgtaaaaga gattaaatta aatggaggag ctaaaatgtt ggatatagtt
    20521 atgatagcat tgttattcat aggatttgtt tccatgaagt tacttgctga ttggtgtggg
    20581 aaacaaactg aaaaaaaata atgtaatgta tggagggatt acctatgtgg tttctggcag
    20641 ttgtaattat aatgttaata atatatttgg tatatgcgct tattaatcct gaaaaatttt
    20701 aaacagtata aggctaataa gtaagttgaa ttggggggaa caatttttat ggtgcagata
    20761 gtaatagtgt tagcgatttt tatgatttta gtaataccta tgggcaagta tttatatcat
    20821 atagctacta atcaaaaaac atttggagat agactatttg ataaagtgga caattttata
    20881 tataaggtat gtagtataga taagaaaaaa gaaatgaact ggaaacagta tgcattagct
    20941 ttattattta caaatgcagt tatggtattt ataggatata tcatacttag aactcaaagt
    21001 atgcatattt ttaatccaag tggaattaaa agtatggaac aaggactatc atttaataca
    21061 ataataagtt ttatgacaaa tacaaatctt caacattatt caggtgaatc aggactttca
    21121 tactttagtc agatgacagt gataatatat atgatgttta catcagctgc aacaggatat
    21181 gcggctgcta tggcatttgt aagaggtcta gtcggtaaaa agaaaacatt gggaaatttt
    21241 tatgtagatt taattaggat aacaacaaga gtacttttac caggagcttt aattattggg
    21301 cttatattag ttacacaagg agtaccacaa acttttgctg ggacagaaac agtgactact
    21361 atagaaggaa agcttcaaga tatagctaga ggtcctgtgg cagctcttga atcaataaaa
    21421 catttaggaa caaatggtgg tggattcttt ggttcaaatt catcacaccc atttgaaaat
    21481 ccaacaataa tatcaaatat agtagaaata ttatctatga tgatattacc aggagcttgt
    21541 gttgttgcat ttggtcacat gataaagaat aaaaaacaag gttgggttgt gtttggcgca
    21601 atgtcaatca tatttttaat aggtctagta gtgtgcttta aagcagaaag tgcaggaaat
    21661 cctattttat cacaattagg gcttaatcaa agtatgggaa gtatggaagg taaggaagtt
    21721 agatttggta tagcacaatc atcattattc acaacagtga ctacttcctt tacgacaggt
    21781 acagttaata atatgcatga tacactgact cctttaggag gattagtacc acttttaaat
    21841 atgatgctaa atgtagtatt tggtggtaaa ggcgtaggtc tgatgaatat gttgatgtac
    21901 gctataatag cagtattctt atgtggatta atggtaggaa gaacaccaga gtttttaact
    21961 aagaaaatcg aaggaaaaga aatgaagctt attgctttac ttattatatt acatccactt
    22021 ttaatactaa tgttctctgg tctttcagta gcaataccag cagggcttga aggaatttca
    22081 aatcctggat tccatggatt atcacaggta ttgtatgagt ttgcatcttc agcagccaat
    22141 aatggttcag gatttgaagg tctaggagat aacactatgt tttggaatat aacaacaggt
    22201 gtagttatgt tctttggaag atatgtgtct attatagtac tactagcaat atcaagtttg
    22261 ttagcatcta aaaaagctgt aaatgaaagt ataggaacac ttagaacgga taattttaca
    22321 tttacaatag ttttagtact tgttgtttta attgttggtg ctttaacatt tttcccagcc
    22381 ttagcgcttg gacctatttc ggagcatcta gtgttgtggc actaaaaaat tgggagggag
    22441 taaagtttta tggaaactaa aaaaacaaag tttattacaa aagatatttt caaaacttcc
    22501 attatagaag cttttaaaaa attaaatcct aaatacatga tgaaaaatcc agttatgttt
    22561 gttgtagaaa ttggatttat agtaacattg atacttacaa tagtacctag tttgtttggt
    22621 gatgaaggca ataacttaag agcttataat gggattgtaa caataatctt atttataaca
    22681 gtcctttttg caaattttgc tgaagctgta gctgaaggaa gaggtaaagc tcaagcagat
    22741 acacttaaga aaactagaaa agatacagta gcaagggtta tagatacgtt aggaaatgaa
    22801 aaaatgataa gtgcaagtga gctaaaactt ggtgatattg ttttagtaaa tgctggagaa
    22861 gttattccaa atgatggaga agttatagag ggtatagctt ctgtggatga gtcagcaata
    22921 actggagaat ctgcacctgt catgagagaa tcaggtggag atttcgcatc tgttacaggt
    22981 ggtactacag ttgtaagtga ctggttaaag ataagaataa caacaaaacc aggagaatcg
    23041 ttcttagata aaatgatagc tcttgtagaa ggtgcttcaa gacaaaaaac gccaaatgag
    23101 attgctttaa atactttatt agtagggtta acacttatat ttatggttgt tttaatatct
    23161 ctttatccaa tggcaaacta tgcaggtgta aagattccaa tttctactat gatagctctt
    23221 ttggtatgtt taataccaac tactataggt ggattgttgt cagctattgg tattgcaggt
    23281 atggatagag taactagatt taatgtaatt gcaatgtcag gaaaagcagt agaagcttgt
    23341 ggagacgttg atactatgat tttggataag acaggtacga ttacttatgg gaatagactt
    23401 gcatcagaat ttatagcagt tggaaatgca gattcaaaag atttaataaa ttattctgtt
    23461 atgtgttcat taaaagatga tacaccagaa ggaaaatcta tagttgattt aggtatgaaa
    23521 ttaggttcaa caggtaagac aaaagaggca gaggaagctg agtttgtaga attttctgca
    23581 caaactagaa tgagtggtat taacttagct gatggtagag ctataagaaa aggtgcttat
    23641 gatagcataa taaaaagagt aaaagaatct ggtggtacag tgccagaaga tttagaagaa
    23701 aatgtaaatc gagtagctaa actaggagga acacctttag tagtgtgtgt agataatgag
    23761 atatatggaa ttatctactt aaaagataca gtaaaatcag ggcttgtaga aagatttgct
    23821 agacttcgag agataggaat aaagacaata atgtgtacag gggataatcc cttgacagca
    23881 gctacaattg caagagaagc tggagtagat ggatttattg cagaatgtaa accagaagat
    23941 aaaatagatg caataaaaaa agaacaatta gagggtaaaa tagttgcaat gacaggtgat
    24001 ggaacaaatg atgctcctgc acttgctcag gcagatgtag gtcttgcaat gaatagtggt
    24061 acaacatctg caaaagaagc agcaaatatg gtagatttag attcagaccc aactaagata
    24121 ttggaagttg ttgaaatagg aaaacagctt ttaataactc gtggggcttt gacaacattt
    24181 agtatagcaa atgatgttgc aaaatatttt gcgattatac cagctatatt tactcttgca
    24241 atacctcaaa tggagatatt aaatgtaatg aaactttcta cgtcatttag tgcgatatta
    24301 tcagctttaa tatttaatgc tataattatc ccatgtttaa tacctcttgc aatgaaggga
    24361 gtaaaatata gacctatgaa atcacaagct atgttaatga gaaatatgct tatatttggt
    24421 cttggtggag ttatagtacc atttttagga ataaaattaa ttgatttatt gattacacct
    24481 ttagtaatgg ttcttaattt aggttaataa atggaggata taaaaatgaa aacattaaag
    24541 ccagcattac ttgtaagtat tgtattgtta gttgtttgtg gacttgtata tccacttgtt
    24601 ttgacaggtg taagtcaagt tgcatttaaa gataaagcca atggaagtat gatagaagta
    24661 aatggtgtaa aagtaggttc agaacttatt ggtcaaagct ttacagatgc gagattcttt
    24721 aagggaagag tatcatcagt aaactataat acttatacaa aagaagattt agtaccagat
    24781 aaagatggaa atacatctta tggaggtgta tcatcagggt cttttaatta tggagctaca
    24841 aatccagaac ttcatgatag agtacaaaaa gatatagaaa agtttttaaa ggataatcca
    24901 actgtcaaaa gagaggatat accaacagat ttacttacag catcaggttc aggacttgac
    24961 cctaatataa gtccagcctc tgcaaaaatt cagataccag ctatagcaaa agcgtctgga
    25021 atatcagaaa gtaaattaca aaaaattgta gatgataata cttccaaaaa actttttgga
    25081 gttttaggtg aagatagagt taatgtatta aaagttaatg tagaggtcgc aaaaatatta
    25141 ggtcttatat agtattttgt ggaattttag caacaaaata ttacgcaaga tttaatttaa
    25201 aggttaaatt ttaaagagtg aaaatcgata atgattttca cttttttatt tgaatattac
    25261 taatatttgg aataaagtga ttgtaagtat aaaatccaaa aaaaggttgc attatcaaaa
    25321 tgataatact ataatatatt tatcgttatc aatttgataa tagatttgga catataggag
    25381 gaaatagtat gttatataat aacgcattag agttgatagg aaacacacct gtagtaaggc
    25441 tgaataattt aggctgtact aatgggtgtt ctaacatata tgtaaaatta gaaaaagtaa
    25501 atccagcagg aagtataaaa gatagagctg tttatgaaat gttagagggc ttagagcaaa
    25561 gaggagaatt aaaaaaggga gatgtactag ttgaagcaac tagtggaaat actggtattg
    25621 cattatctat gataggaaaa ttaaaaggat atgaagtagt aatcgtaatg cccgaaacaa
    25681 tgagcgttga gagaagagat ttaatgaagg cttatggagc aaatttggtg cttacagatg
    25741 gtaaagctgg aatggcaggt tccatagaaa aagcaaatga acttttaaaa gaaaatccaa
    25801 actataaaag cctaaaacaa tttgaaaata aagataatcc aaatgcacat tataaaacaa
    25861 cagcagttga aattatgaat gatgtcaaag atttagatat attcgtatgt ggagttggaa
    25921 caggtggtac tttaatagga actgcaagat atttaaaaga acaaaatcca aatataagag
    25981 taattgcact tgaaccaaaa aaatctccag ctatatcaga aaacaagact ggacctcata
    26041 aaatacaagg aataggtgct aactttgttc ctgaaaatta tgattctagt gtagttgatg
    26101 aagtaatatt agtagatgat gaagatgcat ttgatacagt taaattactt gcagcaaaag
    26161 agggaatttt agtagggata tcttctggag caaatatatt tggtgctata gagatggcaa
    26221 aaaagtatcc agataaaaag atagttacag tagctccaga tggagttgat aagtatatgt
    26281 ctatgggaat attttaataa ttttatttga gggagtgaat actttgttta agaaaataaa
    26341 taaagatatt gaatatataa tgaagaatga tccagcagct aggtctaaga tagaagtttt
    26401 tttactttat ccatcagttc atgcaatgat aatgcatagg atggctcatg ctctttataa
    26461 gaagaagaag ctttttacag caagattaat atcccagata tccagattta tgactggcat
    26521 agaaatacat cctggtgcta aaatggggga aggtatattg atagaccatg gaatgggtgt
    26581 tgtaattgga gagacagctg aagtagggaa tagggtgaca atatatcaag gagctacttt
    26641 aggagctaca ggaaaagata ctggaaagag acatccaact gttggtgatg atgtattaat
    26701 tggtgctgga acaaaaatac taggaccttt aaatataggt tcaaattcaa aaattggtgc
    26761 aaattctgtt gtcgttaagg atgtacctaa tggtgcaaca gttgttggta taccagcaaa
    26821 aatagtaaaa ataagaaacc tagaacctgt aaaaaagaat aaaaaagaag tgtcctatga
    26881 gtatgatgaa ttagataatg tatattatat ataggattta tataactata aaataaactt
    26941 tataaaaatt attttaaaag gtattttttt caaatttgag gacataataa aaaagaactg
    27001 aatgttacag ttttggttca tcaatctttg ataaacaaga ttttaaattt gtagcgtcta
    27061 ggaggatttt attatgaaag caaatgttaa tcaagatact tgtataggtt gtggattatg
    27121 tccatcaata tgtccagaag tatttgatat gaaggatgat gggaaatcac atgttatagt
    27181 tgatgaagta ccaagtgatg ctgaagaatc agcagcagaa gctagagaaa gctgtccagt
    27241 tgatgcaata gatgtgcatt aataaaataa atgcctataa aaattgaatt ttcaattttt
    27301 ataggcattt gtcttttatt cagttagtat ttcaacacct gtttctgtaa ctaaaaccat
    27361 acattcccat tgagcagata atttaccatc ttttgtataa atagtccaat tattttcttc
    27421 atcaacaaaa atttcgtgag ttccttcatt taccataggt tctattgtga atatcatccc
    27481 aggaaccaat agcatctcag tccctttttt agatacataa cttacaaaag ggtcttcatg
    27541 aaagcttaat ccaactccat gaccacctat ttctctaaca acagagtatc catttttctt
    27601 tgcataagag ttgatagcat cacctatatc tcctaaaaat ccccatggtt tggcaacttc
    27661 aagacctttt tggacacatt cctttgtaac ttgaactaat ttttttgcat tttcattaac
    27721 attacctatc ataaacattc ttgaagcatc tgaatagtat ccattaaaaa tagtagaaac
    27781 atctacattt ataatatctc catcttttaa gataatgtct ttacttggaa taccatgaca
    27841 aacttcatta tttactgatg tacatacact tttaggaaat ccattatagt ctagtggagc
    27901 agggatagct ccattttgta gtgtaaagtc atgaaccaac ttatttatat cttctgtaga
    27961 cattccaatt tcgattttat ctgaaatata atccaaaatt tttgtgttta ttacagcact
    28021 tttttttatt tcctcaattt gactttcatt ttttataata tcatgagttg gtacaatatg
    28081 acctaactta gcaaatgaat ctattttatt atccatatcc atatgacatt ttttatattt
    28141 tttagtactt ccacaccaac agctatcatt tctatttaac ttcataactt ttcatccttc
    28201 ttttattatt tatttaaatt atgggttaca taaactattt taaaacataa ccattataaa
    28261 tattataaca taaatactaa gaaatccttt atagatagtg atttattcaa agtataaatt
    28321 attatatggt tattgttgat gaaaagagga tagttaaatg tattattgga tattagcgca
    28381 cttaatagtt tagttcaagt ttttcaagaa aatcatatgt tagaggacaa ttttccttta
    28441 aagtattttt tgaatcttca tcaagataat aatgtacaaa tgattctgca aaaaattctt
    28501 ctataaactt gcttatatat gcatgtgcaa cttgcttagg gtcataaagc ttatatcttt
    28561 cctgagcaaa tacttccata aattcttcag aatttgattt tttatttaaa acatttttat
    28621 ctatagcatg tgcagtttca tgtaattcta aattttttga tgaatgtaca tttgcatagc
    28681 tagggttact ataacctatt ttagccacta tagaattatt tctatatata ccaggtacat
    28741 ctttccaagt cttgcctgat cttacccaac atggaggtaa ttgatatttt aaatcactaa
    28801 attctggttc atcagttaga tttgaattta ttaattttat ttttatatcc ttttctttaa
    28861 gtgtctgtaa atatttaata tttatttttg caagtctgtt tttcatattt tcaacttcat
    28921 ctttatcata attcaagtca tcaggaagta taagcatttg ttcaattata tctatactac
    28981 tgtcttttat attttcagat tcttcatcaa acttatattg aagagtatta ttttcataga
    29041 tagttatatt tgtattattt tctatagaat aagagtgaat atcctctaaa tctaaaatat
    29101 tcatttgttg taaaatatgt tttgtttcgc cactccatac tactaaagaa agtgaattaa
    29161 aattaattag tggattttct tttgctttta tatcattgct tatatctaca tcaaatacat
    29221 attcaattga gtcttctatg ttaagaccat ctgtattctt tttaatatat aaatacgctt
    29281 gttttaagtc tatataaatc tcatctaaag attcgtcata aaattctgat aaattattag
    29341 taaagagttc ttcacttaaa agttcatttt tatcagttat actttcaatt aaaatattaa
    29401 tttcttttat catatcgtaa atacttattt ttctatttgc tttttcacta gatacattgc
    29461 atggcgcaag agcaatgcaa taaaaatctt tttctttttt ataaaaggct ttaagtgatt
    29521 ttgataaaag tgtaaagtct acacctatct gtaagttgac cttaagtgag tcattttgta
    29581 ataattcagt attatttctt ttagctgtat ttaaattgtt ttccataatc attgccccct
    29641 ttttattagg gtatcataat ttttttatat gtgtcaattt gtttttttga aaattataat
    29701 ttttttgaaa attttatttt ttataatttg tgaatttttt attatagaaa taaatatgtt
    29761 attattatgt caaaatttag cattagattc atgtagagta tgttttatac atatattata
    29821 attaattctt tgaagattgc atattcaaaa tacacaccat tttttttaat tctataatat
    29881 aatatttata tatttaatgt taggatgtga tttaaggtgt attttacata tattataaga
    29941 tgtaaagatg attctctata cactggatat accagtaata tagttagaag aatgaatgaa
    30001 cataaattag gaattaattc aaaatacaca agagcaaagg gatttgaaaa actagaagtt
    30061 tattttgtga ccaacacaaa aagcaatgct atgaagttag aatactatat aaaaaaatta
    30121 actagaaata aaaaattgtc tataataaaa aacccaagta tacttataaa tttaattgat
    30181 aataaagaag attatattat tggtaaggaa atagaacaat taacataaat atttatagta
    30241 acattataat gggtgcatat ggtgtaaaaa cttgacaata aatactattg taatataatg
    30301 aagttataaa tatagtaaat taaaatagct aggggagcca agagctgaga ggtataccga
    30361 cccttacacc tgatctggat aataccagcg taggaaagct tagtaaaaat tcaagtatgt
    30421 attatttgtg atatatgcta tttctaagct atacctattg taggtatagc ttttttaatt
    30481 aagttattta aattaaactt taggaggcaa caatgagtaa ttataaaata ccaacactta
    30541 caatagccgg ctctgattca tctggaggag ctgggattca ggctgatttg aaaacgttta
    30601 gtgcaattgg tacttatggt atgagtgtaa taacagctat aacagcacag aatactaaag
    30661 gagtttttgc tgtagaggat ttaaataaga aaataataaa aaaacaaata gaggcagtct
    30721 ttgaagatat acctccaaga gctgtaaaaa taggaatggt ttcaagtcct gagattatac
    30781 ttgaaatagt tgagaatcta aagaaataca atccaaaata tttggttgtg gacccagtaa
    30841 tgatatctaa aagtggatat tatctattaa agccagaggc aaaagaaaac ttaattaagt
    30901 atttgatacc acttgcatac ataattacac caaatatacc agaggcagaa gaaataacag
    30961 gaataaaaat acataatgta gatgatatga agagagtagg agaagaaata ctacaacttg
    31021 gacctaaatt tgtacttatg aaaggaggtc atttagatgg agaagcagtg gatattttag
    31081 ttggtaaaaa tatatttaaa gtttataaaa gtgaaagaat tgataaaaaa aatacacatg
    31141 gaacagggtg cacattatct tctgcaataa catcttatct agcattagga tatgaaataa
    31201 cagaagcagt aaatctaagt aaaatctata taacagaagc aataaaaaga agttttgata
    31261 taggtcatgg agtaggacca gtacatcatt tttataaatt tgagtaataa
//
LOCUS       DAYAKB010000043        29431 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.043, whole genome shotgun sequence.
ACCESSION   DAYAKB010000043 DAYAKB010000000
VERSION     DAYAKB010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29431
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.043"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            105..1442
                     /gene="rsxC"
                     /locus_tag="ACGI3L_002304"
     CDS             105..1442
                     /gene="rsxC"
                     /locus_tag="ACGI3L_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HFG9198006.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            1465..2442
                     /locus_tag="ACGI3L_002305"
     CDS             1465..2442
                     /locus_tag="ACGI3L_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HFG9198007.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            2442..3011
                     /locus_tag="ACGI3L_002306"
     CDS             2442..3011
                     /locus_tag="ACGI3L_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HFG9198008.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            3024..3617
                     /locus_tag="ACGI3L_002307"
     CDS             3024..3617
                     /locus_tag="ACGI3L_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit E"
                     /protein_id="HFG9198009.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            3632..4207
                     /gene="rsxA"
                     /locus_tag="ACGI3L_002308"
     CDS             3632..4207
                     /gene="rsxA"
                     /locus_tag="ACGI3L_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HFG9198010.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            4223..5194
                     /locus_tag="ACGI3L_002309"
     CDS             4223..5194
                     /locus_tag="ACGI3L_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HFG9198011.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            5414..5998
                     /locus_tag="ACGI3L_002310"
     CDS             5414..5998
                     /locus_tag="ACGI3L_002310"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFG9198012.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            6043..6702
                     /gene="radC"
                     /locus_tag="ACGI3L_002311"
     CDS             6043..6702
                     /gene="radC"
                     /locus_tag="ACGI3L_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFG9198013.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            6772..7833
                     /locus_tag="ACGI3L_002312"
     CDS             6772..7833
                     /locus_tag="ACGI3L_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HFG9198014.1"
                     /translation="MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVRE
                     PSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQK
                     AADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
                     EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERT
                     AENVKINIGSTFKDDEEINMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIK
                     STLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTG
                     KSVEDQEIFEKVLMMNTKN"
     gene            7843..8736
                     /gene="mreC"
                     /locus_tag="ACGI3L_002313"
     CDS             7843..8736
                     /gene="mreC"
                     /locus_tag="ACGI3L_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFG9198015.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            8751..9239
                     /gene="mreD"
                     /locus_tag="ACGI3L_002314"
     CDS             8751..9239
                     /gene="mreD"
                     /locus_tag="ACGI3L_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFG9198016.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            9251..12229
                     /locus_tag="ACGI3L_002315"
     CDS             9251..12229
                     /locus_tag="ACGI3L_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFG9198017.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            12327..13010
                     /gene="minC"
                     /locus_tag="ACGI3L_002316"
     CDS             12327..13010
                     /gene="minC"
                     /locus_tag="ACGI3L_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HFG9198018.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            13034..13831
                     /gene="minD"
                     /locus_tag="ACGI3L_002317"
     CDS             13034..13831
                     /gene="minD"
                     /locus_tag="ACGI3L_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HFG9198019.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            13849..14133
                     /gene="minE"
                     /locus_tag="ACGI3L_002318"
     CDS             13849..14133
                     /gene="minE"
                     /locus_tag="ACGI3L_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HFG9198020.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            14218..15348
                     /gene="rodA"
                     /locus_tag="ACGI3L_002319"
     CDS             14218..15348
                     /gene="rodA"
                     /locus_tag="ACGI3L_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HFG9198021.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            15389..15802
                     /locus_tag="ACGI3L_002320"
     CDS             15389..15802
                     /locus_tag="ACGI3L_002320"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFG9198022.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            16287..16616
                     /locus_tag="ACGI3L_002321"
     CDS             16287..16616
                     /locus_tag="ACGI3L_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9198023.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            16620..17411
                     /locus_tag="ACGI3L_002322"
     CDS             16620..17411
                     /locus_tag="ACGI3L_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFG9198024.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFVFGLLCIIAYFILRFKISLIKNNN"
     gene            17541..18361
                     /locus_tag="ACGI3L_002323"
                     /pseudo
     CDS             17541..18361
                     /locus_tag="ACGI3L_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428476.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(18573..19766)
                     /locus_tag="ACGI3L_002324"
     CDS             complement(18573..19766)
                     /locus_tag="ACGI3L_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HFG9198025.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            20085..21929
                     /locus_tag="ACGI3L_002325"
     CDS             20085..21929
                     /locus_tag="ACGI3L_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HFG9198026.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            21931..22632
                     /locus_tag="ACGI3L_002326"
     CDS             21931..22632
                     /locus_tag="ACGI3L_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03936 family radical SAM-associated protein"
                     /protein_id="HFG9198027.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGAESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            22650..24071
                     /locus_tag="ACGI3L_002327"
     CDS             22650..24071
                     /locus_tag="ACGI3L_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HFG9198028.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            24172..24483
                     /gene="rplU"
                     /locus_tag="ACGI3L_002328"
     CDS             24172..24483
                     /gene="rplU"
                     /locus_tag="ACGI3L_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFG9198029.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            24498..24815
                     /locus_tag="ACGI3L_002329"
     CDS             24498..24815
                     /locus_tag="ACGI3L_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFG9198030.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            24829..25119
                     /gene="rpmA"
                     /locus_tag="ACGI3L_002330"
     CDS             24829..25119
                     /gene="rpmA"
                     /locus_tag="ACGI3L_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFG9198031.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            25230..26507
                     /gene="obgE"
                     /locus_tag="ACGI3L_002331"
     CDS             25230..26507
                     /gene="obgE"
                     /locus_tag="ACGI3L_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFG9198032.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            26559..26927
                     /locus_tag="ACGI3L_002332"
     CDS             26559..26927
                     /locus_tag="ACGI3L_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HFG9198033.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     regulatory      27019..27125
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            27228..28433
                     /locus_tag="ACGI3L_002333"
     CDS             27228..28433
                     /locus_tag="ACGI3L_002333"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFG9198034.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     gene            complement(28634..29200)
                     /locus_tag="ACGI3L_002334"
     CDS             complement(28634..29200)
                     /locus_tag="ACGI3L_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9198035.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
BASE COUNT        11308 a         3304 c         5688 g         9131 t
ORIGIN      
        1 aaaaatacgg atattttttt aacaattgtt aagatttttt aatatatata gtatacttat
       61 agaaggcaga aaaaatgttt ttttatagat aagggggtaa aacaatgaaa ctcttaactt
      121 ttaagggagg gatacatcct ccatatagaa aagagtactc taacacaaag gcacttgaaa
      181 aagctcaagc tccaaagata gtttacattc ctcttcagca acatataggg gcaccagcta
      241 aacctattgt tgaagttggt gatgaagtaa agtttgggca aaaaataggt gaacaacaag
      301 gttttgtttc atgtaacgtt cattcttcag tatcaggtaa agttattgct attgaacaac
      361 atgaagtacc aggaggttca gctcaatgtg tagttatcga aaatgacttt aaggaagaat
      421 tacatgagag tgttcaacca aaaggtcagt tagaggattt gagcaaagaa gatatagtag
      481 gtatcataaa agaggcagga atagtaggta tgggtggagc tacattccct aaccatgtaa
      541 aagtatctcc tccaccagat agcaaggcag aagtagttat attaaatggt gcagaatgtg
      601 aaccatactt aactgcagac cacagattaa tggttgaaaa tccagaagat gttgtgtttg
      661 gtttaagagc attaatgaag gtattagatg tcaaaaaagg atttatagga attgaaacga
      721 ataaaccaga tgctatagaa gcaattcaaa atgtagctaa agactatagc gaaatcgaag
      781 ttgttggcct tcaagtgaaa tatccacaag gagcagagaa acaacttatt tatgcgtgta
      841 caggcaaaga agttccatct ggtggattac caatagcagc aggtgcagtt gttgacaatg
      901 ttgccacagc agcacagata gctaagtcta ttaaaacagg tatgcctttg gttgaaagaa
      961 tcactacaat aacaggtagt tgcatcaaag agccaaagaa cctaataaca aaagttggaa
     1021 cattagtttc agaaataata gaacaatgtg gtggatttaa agaagataag aagattggta
     1081 aggttataat gggtggacct atgatgggaa tagctcaata tactactgaa atagcgacta
     1141 acaaaggttc ttcaggaatt ttatgtttgg atgaggaaga atcacgtact ccagatattc
     1201 aaaactgttt aagatgtgga agatgtacag atgtatgtcc atcattctta caaccacttt
     1261 tcataagtgc atattcttta aaagatgact atgacacagc tgaatatcat agagcaatgg
     1321 attgtataga atgtgggtct tgctcattta tttgtccagc aagaagacca ttacttcaat
     1381 ctataagatc agcaaagaga gaaataggag caaagagaag aaagcaagct gctcagaaat
     1441 aaagaaagtt aagggggaaa aacgatggaa aataagttga tagtatcatc ttctcctcat
     1501 gtgagaagta atgaagatac ttcatatata atgaaacaag ttattatagc actccttcca
     1561 gcagcagtag caggagtata cttctttaga cttaatgctt tgagtgctat gtttttttgt
     1621 atacttggta cagtaggtac tgaattttta tatcaaaaat ttacgaagca aaaaagtact
     1681 ataggagatt tttcagctgt tgtaacagga ttattattag catttaacgt accagcatca
     1741 cttccttggt ggatgtgtct agtaggagga atatttgcaa tattagtagt taaaatggta
     1801 tttggtggaa ttggatgtaa ctttgtcaat ccagcacttg ctgcaagagc atttttatta
     1861 gcatcattcc cagtagcaat gactgcttgg actcaaccag gtgttaactg gataggtaaa
     1921 aatttagatg cagttactac agcaactcca ttaagctttt tgaaaaatgg agcagcagga
     1981 ctggcagacc tttctagcaa tggaattagt cttgctgaca tgatgatagg gaatattggt
     2041 ggatgtatag gtgagacatc agcaatatta ttattattag gtggagtata cctaatgtat
     2101 aaaggcataa taaattatgt tataccagta ttttacatag caactgtatt tatattaaca
     2161 ttccttttag gtggatttaa tataactttc gcaatatatc aactgtttgc tggaggactt
     2221 atgttaggtg gattcttcat gcttacggat tatacaactt cgcctatgac taaaaaaggt
     2281 caaataatat acgctgtatt agctggtctt ataacaactg ttataagaat gtatggtgga
     2341 tatccagaag gtgtatctta ctcaatacta ttagtgaact gtcttgctcc acttatagat
     2401 aagtttgtta gaaatagagt atttggggag gtggctaaat aatgaacagt atggtgagat
     2461 taggtggtac tttacttgct ataagtgcaa tagctgcatt agctcttgga gctactaatc
     2521 aggttacagc tccagtaata gaacaaagaa atatacaagc aaataatgaa cttagaaaag
     2581 cagtccttcc agaagcaaaa gaatttaaag aaatgaagga agatacttac aaaggccttg
     2641 gagatggtct tatagctgaa gtgtatgaag gtttagatgg ttctgaagtg gttggatata
     2701 ctttaaaagc taaaccaagt ggatatggtg gagaaattga agttatggta ggtatatcat
     2761 ctgaaggtca agttacaggt gttgacattg gtaatatgtc agaaacagca ggtcttggag
     2821 caaaagctaa ggatgatgca tttaagggtc aatacaaagg aaaaactgct gagcctcttg
     2881 aagtagcaaa aggaagtaca acagcagata atcaaatatt agcaatatca ggtgcaacta
     2941 ttacatctac agcagttact acaggagtaa atgctgctat agatgttttc aatagtgctc
     3001 ttaataaata aggagggtta attatgaatt tagctaaagt atttaaaaat gggctaatag
     3061 atgagaaccc aacatttgtt caagttatag gtatgtgtcc aacactagcc gttacaactt
     3121 cagcaataaa tggaattggt atgggtcttt caacagcagc agttttaata tgtgcaaatt
     3181 tagttatatc tttaataaga aaaattacac cagataagat aagaatacct atatttatag
     3241 tagttatagc tacatttgtt acaatagtag gtatgctttt aaaagcatat gttcctgctc
     3301 ttgataaggc tcttggtata tatataccat taatagttgt taactgttta atattagctc
     3361 gtgcagaaag ttttgctttc aaaacaggag ctatgccttc aatagttgat ggtgtaggtc
     3421 aaggtcttgg atttactgtt gcacttacaa taataggtgc agtaagagaa ttacttggaa
     3481 atggtagttt atttggaatg acattatttg gagcatcttt ccaaccagta ttaatattta
     3541 tattaccacc aggtgcattc ttaacattag gattcttatt tgcaggattt aataaattaa
     3601 gaagtaaaaa agcatagtgg aggtgtaata aatgaattta atacttttat ttttaagtat
     3661 cgttcttgtt aataacgtta taacatctca attcttgggt atatgtcctt tcttgggagt
     3721 ttctaagaag gttgatacag cagtagggat gggagttgca gttacgttcg ttttaactct
     3781 agcttcaatt ataacttatt ttatacagat tttattagta aaaactggaa ctggattctt
     3841 acaaacaata gcttttatat tggttatagc ttctatagtt cagttcgttg aaatggtaat
     3901 tcaaaagatg agtccatctt tatatcaagc attaggagtt tatttacctc ttataactac
     3961 aaactgtgca gttcttggta tagctctagt taatgttcaa aaaagttata atttagtaga
     4021 aacaataata aacggatttg gagccggagc tggatttact ttagcaatag taatattcgc
     4081 aggtataaga gaaagactag aattagctga tataccagaa gcatttaaag gtttccctat
     4141 aacgcttata tcagcaggtt taatgtcaat agctttctta ggatttacag gacttataaa
     4201 gctataaaaa agaggggtga aaatggtgat acttacagct gtattagttt taggaattat
     4261 gggcttaatc ttcgggatag tactagattt tgcatctaaa aagtttgctg tagaagtaga
     4321 cgagagagtg gaagctatac taggagtact tccaggagcc aactgtggag gttgtggatt
     4381 tccaggttgt ggaggtcttg caaatgcgat agttgaaggc aatgcaccag ttaatggttg
     4441 ccctgtaggt ggagcagatg ttggtgcaaa agttggagaa ataatgggaa taagtgctga
     4501 agcaggtgag aaacaagtag caaaagttat ttgtaaagga acttgttcaa gtgcaaaaga
     4561 taaatatgag tatgaaggaa tatcagattg tagagcagca aatgttttaa actcaggtgc
     4621 taagatgtgt aaatttggat gtttaggtct tggaacatgt aaagatgctt gtaaatttga
     4681 tgctatttct atagttgatg gaatagcagt aatagatgaa gaaaagtgtg taaattgtgg
     4741 aaaatgtaaa gaagtttgtc ctaagggtat aataatcaca aaaccagaaa gtcaagaagt
     4801 agttgtagag tgtaatagca aagagtttgg taaagctgtt aaagaaaaat gtactgctgg
     4861 atgtattggc tgtggaatgt gtgtaaaagc ttgtaaattt gatgcaataa tatttgaaga
     4921 caaaatagct aagatagacc ctaataagtg tgtaggttgt atgcaatgtg tagcaaaatg
     4981 ccctacaaaa gtaatatcag gtgacataac taagaaaaag aaagttacta ttgaccaaga
     5041 actttgtgtt ggatgtacag tgtgcaaaaa acaatgtaag tttgatgcaa tagagggaga
     5101 attaaaagaa aaacataagg tagatgcaga taaatgtgta ggatgccatt tatgtatgga
     5161 aaaatgtcca aagaaagcta ttaaaatttt gtaatatgga caaaataagg atatggaata
     5221 atttccatat ctctaatgag tacataaaac agaggtatgg aataatttcc atacctctat
     5281 tttatgtata tttattctaa tggtaataaa tataacaata gtgtaacaaa aaaggttcga
     5341 catttctgtt gaatttttta caatatagtg atagactaaa taggtacaaa ttacgtacaa
     5401 atgaggtgaa taaatgaata taatcttggc atcagcctct ccaagaagga aagaaattct
     5461 agagaatacg aatgtaagat ttgatataat taaaaatgaa attgatgaga ttatattgga
     5521 aggtgaaaca ccaaaacatt tagttatgag attagctttt gaaaaaagta tgtctgtagc
     5581 atctgaacat aatgaagatg ttgttattgg agctgataca gttgttgttt tagacaatgc
     5641 tattttagga aaaccaaaag atgagtcttg tgcaagagat atgttaaaaa gactatctgg
     5701 aagagagcat caagtcataa caggtattag cttaataaac ttgtgcgaag ataaaaaggt
     5761 aattgactat gtaatcagca atgtgaaatt taaaacgtta tcagagcagg atattgagga
     5821 ttatctgaaa actaatgagt catttgacaa agcaggagcc tatggtatac aaggttatgg
     5881 agctttgtta gttgaagaaa ttagaggaga ttattttaat atagttggtc ttccaatttc
     5941 aaggttaggc gacctattaa aaaaatattt tagtataaat cttttttatg gagtgtgatt
     6001 tatctgaaaa agtcatttaa ttcaaccatt aaggtaaaag aaatggcacc agaggaaaga
     6061 cccagagaaa agatgcttgc caaaggcgta aaaagcttat caaatgctga gttgttggct
     6121 atacttttaa gaactggcaa caagaataaa aatgctattg aattagccaa ctatataata
     6181 aatagagata ttcagggtat tagacattta gaagatatga caatagagga gctgtgtaat
     6241 atagatggaa ttgggttatc aaaatcaacc caaattaaag cagctttaga actaggctct
     6301 agagtagcta gttttaaacc tataaagtat aaaataagga atccttggga tatacagagg
     6361 tattatatgg atagcctaag gtatttaaaa aaagaggttt ttaaagcggt tcttttaaac
     6421 acaaaaaatg agataatatc tgatgtagat gtatctatag ggactttaag ctcgtcatta
     6481 gtccatccaa gagaggtttt taaagaagct ataagaagaa gtgcaagtaa gataatagtg
     6541 atgcataatc acccttcagg aagtgtagaa ccatcaagag aagataaaaa tatcacatca
     6601 agacttatta aatgtggaga aataattgga atagaaataa tagaccatat aattattgga
     6661 gatggattat actttagctt taaagaaaat atgataattt gactttatat gtgataaaat
     6721 aatagaagaa tgttttaaac atgattctta atagtaggaa ggagtaaaat catggctaag
     6781 gaaaaaaaga aagaaaaaaa aggttttttt agttttaata agatgacaaa ggatatggga
     6841 atagatttag ggactgcaaa tacattagtt tacataaaag gacaaggtat tgttgttaga
     6901 gaaccatcag ttgtcgcaat aagagatgat agtaaagagg tattagcagt aggtgaagaa
     6961 gccaaaaaaa tgataggtag aacaccagga aatatagtag ctataagacc tatgaaagat
     7021 ggagtaatag ctgattttga cataactcaa tcaatgatta gctattttat acaaaaagcg
     7081 gctgataaaa aaggtgttgt aagtccaaga atagctatat gtgttccttt tggagttaca
     7141 gaagtagaaa agagagctat agaagaggct gcaagacaag caggagctaa agatgcattc
     7201 cttatagaag agccaatggc agcggctata ggggctggat taaaagttga agaaccagaa
     7261 ggtaatatgg tagttgatat tggtggaggt acttcagaaa tagctgtaat atctttagga
     7321 ggaatcgtta ctgctaaatc tataagaata ggtggagacg aatttgacga gtctatagtg
     7381 gcttatgtaa aaaaagaata taatcttatg ataggtgaaa gaactgctga aaatgtaaaa
     7441 attaacatag gttctacatt taaagatgat gaagaaataa atatgcaaat aagaggtaga
     7501 gatttaatct caggattacc taaaacaata gaaatatgct ctacagaagt tagagaagca
     7561 ttaaaagaac ctgtaagttc aatagtagat gcaataaaat ctacactaga aagaactcca
     7621 ccagaattag cctcagatat aatggaaaac ggaataatgc taacaggagg aggcgctttg
     7681 cttagaggtc ttgataagct tattacacag gaaactggta tgtctgtaca aatagcagaa
     7741 acacctcttg attgtgttgc acttggaaca ggtaaatctg ttgaagacca agaaatcttt
     7801 gaaaaagtat taatgatgaa tactaagaat tagaagttgg tgatggcctt gagatttgac
     7861 aagaacaaaa atgagaaaaa aaggattaat gttaaagtga tagcaacggg cgtagttgct
     7921 atcactttaa ttggaattgt gggtatatca attggtaaat tttctagtgg tagtccagta
     7981 aatttaggag tagcttcaga tgctattaca agtgtaggta agggaataaa tgatggattt
     8041 tcttttatca aaaatggttt taaagatgta gcaaatttta aagataattc taaaaaggta
     8101 aaaaaattag aagaagaaaa tgaaaaactt aaaaaaaata tgatagcttt aaatgccaaa
     8161 ctagataaaa cagaatcgct agaagagtta aaaaagacac tgaactttgt acaagaagag
     8221 tataaggcga caagtatttc agcaagtgtt gttggtaaaa atgatggaaa ctggtatgag
     8281 agttttgtca taggtgcagg aaaaaattca ggtgtaaaaa aagaaagtat agttatgaat
     8341 ggtagtggat tagttggcat agtttatgaa gtttccaaca attatagtaa ggcaatttca
     8401 ctattggatt ctaaggcatc tgtaagcttt aaactagcaa aggatgccaa tgctaaaggt
     8461 acaattactc aaaatactac tttagataat aaagatagtt ataatagtaa aggatatttg
     8521 caaggatata tgtttgactc atcatataat gtaattcaag gagatataat aacaacatca
     8581 ggtcttggat tcttcccaga tggtatacca attggcgaag ttgaaaaagt ggttgatgat
     8641 aaagataagt cattaaaata tgtagttgta aaaccttatg ttgattttaa gaatataaat
     8701 gacgttgtag tcatagaacc aagaaatata ggataaaggg gataaaaaca atgaaaaaag
     8761 ttttactttg tctgttgggg attgtgctta tgactataga aaatagtata acaaattata
     8821 tagatatttt tggcataagc tttaatttag ttcttatata tgtaaccata atctctcttt
     8881 atttagatga attagaaggt gggattatag cagcaataat agggcttatt aaagacataa
     8941 ccgttggtgg aatttttggt gtaaatgcat taattttgtt tattattgca tatgcaattg
     9001 gatacatgag agatcagcta tataaaggta gttatattat tactttcgtt ttaattttta
     9061 taggcagttt aattgattca attgtcaata taggtacatc tagtataatt tatcaaagct
     9121 acaacatatc aacacttttt gtaaaaggtc tactagtagc accaatagtg aatagtttaa
     9181 ttggtttagt aatatatcgc ttatctaaaa gagcagtttt aaaacttaaa gaagattagt
     9241 tggtgatttc atggaagaaa ataaacaagt tgatagacta aaaataatta agatagtcat
     9301 gggcgtgata tttttagcta ttttagtaaa aataatctat atgactacat ttaaatatga
     9361 atattacaat gagttagctg agaataaaac atataaaaag ttggcaatag aagctccaag
     9421 aggagaaata aaagatagat atggaagact gttggcagga aataaaaact tatttactgt
     9481 tcaagtttca ggtaacgata ttaataagaa agatgcaaat aagcattcaa gagcaaatga
     9541 aatatcatta aaacttataa atttgctgga gagaaatggt gaagaatatg tagatgagtt
     9601 tcctatatat gtagaaaatg gaaagtacta ttatacatat gacagagata ttagggaata
     9661 taaatcagaa aatggtattc caaatgatta taatgctaag gaaagttttt attacttggt
     9721 ggacaaactt atatcagctg gaatattatc tcaagaagat aaaagattgg atgcgacaag
     9781 attacaggca aaactaaatg aaaatggata ttatccacct attttagtta gtaaatggat
     9841 gttcacagca gaaagagata agagagattg gttggctagt tataagataa aagaaactaa
     9901 actgagtgcc aaagaagcgt ttgaaaaagt aagaaatagt gatgcattag aaattgataa
     9961 aagtttgagt gatgaagatg caagaaaaat aatggtcgta agggatttga taaaatcaaa
    10021 aggatattct caatataatc cagtaactat tgctaaggat gtaggagaaa ctacgattgc
    10081 tcaaattgaa gaaagtgcta tggaccttgt tggtgtttca atagcagtag aaccagtaag
    10141 atattatcct aatgggtcat tagcttctca tatgttagga tatgtaggaa aaatgccatc
    10201 cactcaaata gaatcatacc ttcaaaaagg ttatgaaact ggagatatgg taggtcttgc
    10261 aggagtagaa aagagtaatg aaagtagatt aagaggaact gatggttata aaatggttaa
    10321 agttgatgca ttgggtagaa tcagtaaaga aattgaatct aaaaaaccta aatcaggaga
    10381 tactgtgtat cttacactag ataaagattt acaagaagtt tcagacaatg cattaaaaca
    10441 gataatcgaa gttgcttcta aaggaggtac ttttaaaagt aaatttgggg acaaaccaat
    10501 tagtgcatat gcaggaaaag cacagtcagc agctcttata gctattgatg ttaaaaatgg
    10561 agaagtatta gcttcatcaa gttatcctaa ttatgaccca aataaatttg caaaaggtat
    10621 ttctacagag gattataaag cacttcaacc aaaaaatcca aatgacttac tagcaggaag
    10681 tccactttta aacttggtta cacaagggga atttcagcca ggttcttcat ttaagatggt
    10741 aacttcaatg gcagcgttag aaaatggtct ggatccaaac tttactataa atgaccctgg
    10801 ggttataatg ttaggtaaaa aatcttttgg tgactatgta tggaaccatg gtagaggaaa
    10861 ccatggtatg acaaacttat ataaagcaat acaagagtct tgtaatatat atatggcaac
    10921 aattggtaca ggtaaaacat ggccagatgg aaaaagcatt ggtatagata tgaatgcaaa
    10981 taaaatactt gagtatgcaa aattatttgg gcttgaccaa aatacagggc ttcaagatga
    11041 agtagaagaa agagcaggta aagttcctag cacagaagat aaattgaaat caacacaagc
    11101 tcttctaaag tcaaatttag aaagagaaat ggcaaatgat tttgttgata taactagaga
    11161 aaaaaatcct aaagaatatg agaaaagaat caatgagatt gtaagctggg cagcagaaaa
    11221 gaaaactcct ggtagagttg aaacaatgaa taggctaaaa aaattggatg ttaaagaaga
    11281 tagaattgaa gaagtagcag atttagcagt atttagttat tttaactttg caaaatggag
    11341 tactgcagat acatttaact tagctatagg tcaaggtgaa aatgcttata caccagctca
    11401 aatatcaaga tatgtagctg ctatagcaaa tggaggtaat ttagtagaat tatctgtagt
    11461 tgatagagct gtttcaagtg attattcatc agttaaaatt aatgaccaga agaaagtcga
    11521 aaaaatacct tttaaaaatc cagataactt aaaagaatta acaaaaggta tgaaattggt
    11581 tgcaagacaa ggtacagcga agagtgcttt tgctgatttt ccaatagatg tagcagcaaa
    11641 aactggtaca gctgagaaaa gtgggaaaat acctacagat aacgagtatg aatatttaaa
    11701 aagtcatatg tcatcttata atgtcaacct aaatgatgcg attaaactag ctgataagat
    11761 gaaagcagaa aaagaaaaag agctttcatt agctaaggaa aaggaaataa aaaagaaatt
    11821 agaaaataaa gatttgaaag acgaagaaag aaagaaatta gaggaagaat tagaagatgg
    11881 agtaaaagtt agattagagg acactgataa ggtgaattct tcatatctaa gaaaagctat
    11941 aaaagaatta aatccaaaaa taacagatga ccaaatagat agatttaaac aagattatgg
    12001 ttcttttacg tggactgttg cttttgctcc agcagatgac ccagaaatag ctgttgtatg
    12061 tgtaattcct caaggtgatt caagtgtatt ctcactttta ccaactagag aagttattgg
    12121 aacttatatg ggattagagc caactaatag taaaaatgac aacaagacga atgatgttaa
    12181 caattcttct gacgaaaata taaatttcga gtcacaaatt aatagatagc tcaatctatg
    12241 tataaacttt agctttatat agaaaaaata aaagggttta aagcgtattt gaagaatata
    12301 aatgatatat cactctggag gttgttatgt ctttaagaga aatttgtagt caagaactag
    12361 tagagttcaa gggtaataaa agagggataa tagtaaatat aaaaagagaa gctccatttg
    12421 aggaaataca ggaaaaaata ataaacaaat tggaagcata tgttggcttt tttaatgggg
    12481 ctaaaattag taaaattaat agtgattgtt taactgacat ggagattcta gaacttaaag
    12541 aaggaattac ttctagattt gatgtggaat ttgttgaaga tcaaaaaatt gaagaaaata
    12601 gtaattttcc aacaaaatat gtcaataccc taagatctgg tgaaaatatt gaatttgaag
    12661 gtgatgtagt tatattgaat gatatgaaac ctggttcaaa agtcctttca aaatcaaata
    12721 cagttgttat gggagatata aatgctggtg ctaaggttgt agcaggaggt aatgtttttg
    12781 taatgggtaa aatagaaggt tttgtacatg caggtgcaga aggcaatgaa tttgcatatg
    12841 ttgttgctgg aaatcttaat cctaaaatat tacaaatagc agataatatt gcagaagctc
    12901 cagatgatga agaaaattat gaaagtgaat cagaaattag cccagaaata gcctttgtaa
    12961 gtaatggaag aattgtaatc gaaagctatt tgtcaaagtt agacaaatag aaagaaaaat
    13021 agggggtagt attatgagcg aagttatagt tataacatct ggtaaaggtg gggttggaaa
    13081 aactactacc gcagcaaact taggaactgc gctaagccta gaaaataaaa aaacagtagt
    13141 tgtggatgca gatattggac ttagaaactt agatgtagta atgggtcttg aaaatcgaat
    13201 agtttatgac atagtagatg tagttgaagg aacttgtagg cttaagcaag ctctaataaa
    13261 agacaaaaga tttgataatc tatatttatt accagcagca caaactagag ataaaaatgc
    13321 tgtctcagtt gagcagatga ttgacctgtg tgagaaacta aaagaatctt tcgagtatat
    13381 aataatagat tgtccagcag gtattgagca aggctttaaa aatgcagtag ctggggcaga
    13441 tagagctatt gtagttacta atccagaaat atcagcagta agagatgctg atagaataat
    13501 aggtctatta gaagcaaatg aaataaaaga gataagatta gttataaata gaattagaaa
    13561 tgatatggtt aagcgtggag acatgatgga taaacaagat ataatagaaa tattagcaat
    13621 agatttgtta ggtcttgttc ctgatgatga aagcataatt atatcaacaa ataaaggaga
    13681 gccagctata cttgattcta agtcacttgc tggtcaagca tacaaaaata tcgcaaaaag
    13741 gatactaaat gaagaagttc ctctacttga tcttgaagtt gaagatggat tctttggtag
    13801 acttaaaaaa atgtttagca tggctaagta gcaaaggagg atacatctgt gttagattta
    13861 tttagagttt tttctaacga ggctaaaact agtaaatctg ttgctaaaga gaggttaaag
    13921 ctagttttag ttcatgatag agtagattgt tcaccacaac ttttagagat gataaaaaca
    13981 gacattttga aagtaatagc taattatgca gaaatagaag atgatggtct tgaaataaaa
    14041 atgtctaaat gcagaggtga gcatgatgac aaacctgtat ctgcattagt tgctaatata
    14101 ccactaaaga atataaaaga tagatgtatg taattagtgc ttaaaagggg gatatcctta
    14161 ttggtatatg ccccttttat ttaattatat gtttaaagat agaaagacgg tgattctttg
    14221 aaaaaaatca atattaatta taagtcgaca attaagttga taaaacagtt agactggaaa
    14281 cttatagtta cagtattagc tatctttatt tttgggcttg ttatacttag tagtgcaaca
    14341 catgctaatt caacaggttc atataatcaa ttgattaaac aaggattagc ttttgtactt
    14401 ggtataggaa tgattatagt catattattt tttgactata accttctagg caggtattat
    14461 aaagcgcttt atataataag tcttattttg ttagccatag ttttattacc tggaattggg
    14521 acagtaaaag gtggagctag gtcgtggatt aacttaggac cacttgactt gcagacatct
    14581 gaaatagtca aattaacatt tgtactaagt tatgcaaaga tacttgaatc caaaaaggat
    14641 aaattaaata cgttaaagga agttatgcct gttgtagttt attctcttcc atttatcgga
    14701 ttattgattg cacaaccaga cttgggaaca ggaattgtat tttgttgtat gatatttgca
    14761 atgctgttca cagcaggtct tagttcaaag ttgataaaaa gaggaataat catactatta
    14821 gtgtcaatgc cactgatgta tttaatgatg gcagaccatc aaaaggtaag aatagaagct
    14881 tttctaaatc cagaagatgt aactctaaaa ggaaactatc aagttatgca atctctgatt
    14941 gcaattggtt ctggaggcgt aactggtaaa ggactttaca atggaagtca aaatcaagaa
    15001 gattttttac ctgtacaaga tagtgatttt atatttgctg ttgtaggtga agaacttggt
    15061 gtaataggaa tggcagtgtt gataatctta tttatgatat tcctattaag gcttttagca
    15121 attgcaagag atgcaaaaga tttttatgga accctcatag tggttggtgt tatgggaatg
    15181 tttggttacc agataatcca aaatataggt atgacggttg cgttaatacc agtaactgga
    15241 gtaacattac cttttgtaag ttatggagga agttcgttat tgacatcttt agcaaactta
    15301 ggattagtac taaatgtgtg tatgagaaga aagaaaataa atttctaaat ttaaatacat
    15361 ctaaacataa attgaggaga ttagatatat gaatatagca ttagtagcac atgaccaaat
    15421 gaaaaacact atggtcggat tttgtatagg ttatgaatca attttaaaaa agtatggact
    15481 atatgcaact ggaactacag gaaaaagaat aatggatgaa actgaattaa atataaatag
    15541 attagcatct ggtcctttag gtggagacca gcaaataggt tctttaatag taacacaaga
    15601 aatagattta gttatttttt taagagaccc attgacatct caggctcatg aaacagatat
    15661 acaagcgtta ataagacttt gtgatgttta tcatgttcca atagctacaa atctagcttc
    15721 agcagaaata tttataaaag ctcttgatag aggagaacta tcatggagag aagttagaaa
    15781 aagcaaaagt caacgtattt aaaaaatatt aatattacag tctaaagaaa cagatatata
    15841 agtgtttaat gccctagttt ttctgttgga ataaatctag tacctgtaga aatcttatga
    15901 aagatttaaa tgatgaagag ctaaatttga gattaaataa ttaggaaata gattatagat
    15961 agagtagtag aatttaaact attactctat tttaataata tgaaatagaa tcaagtctat
    16021 tattatatat atttaaactt ataggtaata ctatttcaac caagtaaatg ttgttatgac
    16081 aacattaata aaacaaaaat ttatttttaa aatttgataa atagctgtat attagtattt
    16141 atagattaaa tattaatata cagctattta ttatttttaa gtctattgta gaatataaac
    16201 cttgtattat agagtactat gtaatattat agtaaatata agtactatac attatagagt
    16261 agtaggtgaa aaggcggtgg tacataatgc agttaaataa agaagtgtta aaaggttata
    16321 tcgatatatt aattgtttct atattagaaa agaaagattg ttatggatat gaaattgcaa
    16381 agcaagtaag agaaagaagt gagtttgaat taaaagaagg aacaatgtat cttgcactta
    16441 aaagaatgga atctaaaaat ttaattaaat cttattatag caatgaacaa agttcaggtg
    16501 gaagaagaaa atattataat ttaactaatg aaggtaaaga ttttttagaa ataaagaaac
    16561 aagaatggag atttattaaa aaggttatga atcaattttt gggagaggtg gattaattta
    16621 tgaaactaat agatgaatat ttagataaac tatataaaaa atgtgacaat aaaagtacta
    16681 tagaattaaa acaggaaatg agatgccatc ttatagaatc tgcaaatgaa tttaaattag
    16741 aaggattaga tgaagaagaa gcatgtaaaa aagcaattga aagatttgat gatggtgatg
    16801 aaatgcagta tgaattatgt aatataataa aagaactatc tttatcattg gataggcata
    16861 aatcaattgt aatggggttt aaaaaagtat taggttacat aagtataatt gcatttttaa
    16921 tttctggatt tatgtggtat tacaataata gtttacaaca taatatgtat aatttaggaa
    16981 aagaacttga tggagaaata aagcaattgg cagaaagaca tgatatgaca aagattggtg
    17041 aatataagtt agaacttgaa aaaatacttg ataaagataa gtatagtaaa gtcaaagctc
    17101 ttagactata tgtaatagat atgaaagatg gaaacactaa tttaagttct tctggattga
    17161 atgctaatat ggtatatgag agggaagcag attataataa cataagtaat tttatacagc
    17221 atttaggata taatggaaaa gattttttag acaagaatgg gaatatagta aatccagata
    17281 ttttcttaga atatttcttt tattttgaat cggagatgtt aattccagta gcattcgtat
    17341 ttggattatt atgtataata gcgtatttta tattaagatt taaaatttct ttaataaaaa
    17401 ataataatta aataattcac caaataattt taatttgtag agtaaataag atgtttcaaa
    17461 ataaaatttg aatcatctta ttttttattg tttgttatat tcttttcttt tatatttctc
    17521 catagtggat tgtatctata cataatcaca ttaaaaacaa cacaacatat gttaactgga
    17581 acgcagcaga gggagccaat actgcttata cattggttac taaaaaaggt gcttgttctg
    17641 gaatgtgtag gagcttgaaa gctttatgtg atgctatggg aattgaatgt tattatgtac
    17701 atagtacaac aaatgaccat cagtggaatc ttattcgttt tgaggatgga cgtttgtatc
    17761 atgtagatat tgatgccaac aaatcagcag gagcagacat catatacaag agtcttactc
    17821 acccattacc atttgacaag aaagcatatc cagctgttgg cgaagtagta aagacacaga
    17881 atccaacgcc aactgttaag aaacctacgc cagctaagcc ttctgcgcca gttggacctg
    17941 ggaatcacac tatgatagca gatcaacaag gggcaatact tgatgaagtt tatggaaata
    18001 atctacgtcc aaaaattgaa atgtatgagg gagttccgtg tagtttaatc aactcatcaa
    18061 taaatacaat taagtttaca agcaaaaatt caaatttaga cccatcaaag catacagtta
    18121 ctgtaatagg gtttatgaat acaccatatg gtatggttgc attagcacca gagagcaaac
    18181 ctgttagtta tccttttgag tatgataagg cattttcttt agattttact ggtaagaacc
    18241 tttctgcagc agaattatca aaaaagtgta aaaaaataat ataattatta aagtagaaat
    18301 tggtgaaaca acatctaatt ctggaatagg gctagtagca tatactagat acgtgaatta
    18361 atacaagtat actagtatac aaatagaaca gactataaat aatgcaccct gtgcgaaagg
    18421 gtacatttat tattatatta gtcattttgg aaaataaaaa aggagttgaa cttaaaatta
    18481 gattagaaaa attaattttg agacaactcc attttaattt atttttaaat ataaaatcat
    18541 ttattttaaa taatattatg tttgattaat ggctatttaa ctaattttgc aaattctgca
    18601 ccaaatgcca tacactcttt taatgtctct tcactaggga agaatttttt cttaagagat
    18661 tctacaggca ttttgaatga catagattta agtaaagtct cagccatagt tataccttca
    18721 ccactccaac caaatgaacc aaatactcct gctatcttgc cttggttagc cattgggtct
    18781 ataacagaga ataaatccca cataggttta accatagttt tgtttatagt tggagagcct
    18841 agtaatatta cttttgacac tactaatgta tcgtgcattt ctgttaatgt catatcttct
    18901 aaatcatata attcagcctt tgcaccttct ttatcaagtc cttcttttat ctttttagcc
    18961 atctctaaag tattactata agctgataag tagaatatag aaacttgatt ttgattagtt
    19021 gtattaacag cttctgtaga ccactcaaca tatcttttaa cagcagccat tgggtcttta
    19081 gtaagcattg gaccatgaga agtcaatata gtatcaaatt ctatgtttag tcctaccacc
    19141 ttatctacag cacttaaaac atgtttagca aatggcttaa ctatacaatc atagtagtgt
    19201 ttagctgatt ttagataatc ttcactattc actacctctg catcaacact tgcaaagtga
    19261 caaccaaatg catcacaagt taaaagagtc ttgtcctcct caatgtaagt aaacattgta
    19321 tcaacccaat gtaagaatgg agcagttata aatctaagat ttcttttacc gatatttaaa
    19381 atttcaccat cttttattac atgacagtta aaaggtctat ttatttgacc atctaagtat
    19441 agtttagcag ctttagtaca ataaacttct atattaggat ttatatctaa taagtatttt
    19501 aaactacctg catggtctgg ttctgtgtga tgaattacaa catagtcaat tttagctata
    19561 tcagtaacct ctgataaatt acttaaaaac tcatctttaa aatttgcctt tacagtgtca
    19621 aataaaaccg ttttttcgtc cttgattaaa taagagttgt aagttgtccc aaactcagtt
    19681 tccattatta tgtcgaatac ttttaaacct tcatctacta ctccagtaaa gtagatatct
    19741 ttttttactt caaaaacttt actcattttt aaccctccta aaatttatca ttatataagt
    19801 aacatacccc attttgaggt gaatgaaaca aaagatgtca tgataagtca tgtaaaacaa
    19861 tagttttatg tttataatat atcatacttt gtaaaaaaat tgtatttcaa taaaaattta
    19921 atagaaaata ttcttaaata tttttagcta ttctattttg tgaataatat gtattttaaa
    19981 ttcaatattt tagttatatt tttgatagaa aatattttat cgtgtataat attacttata
    20041 aataagaata aaaataaaga gcttgtttgg aggaatttta ataaatgaat aaagtagact
    20101 tgaaaaaaat cttaaaaaaa gtagaaaagc ctgctagata tcttggaaat gaaataaatt
    20161 caattcataa agatactagt aatagtgaat tgataagata tgcacattgc tttccagatt
    20221 tatatgaagt tggtatgagt cacttaggga gtcatatatt atatgatgta ataaataagg
    20281 atgaagatgt attttgtgag agagtgtatt ctcctgcagt tgatatggaa aatataatga
    20341 gagaaaaaag tataccatta tttgcattag agtcaagaga gcctataaca aactttgatt
    20401 ttgtcacttt tacacttcaa tatgaacttt catacactaa tatcttaaat atattagatt
    20461 tagccaatat accaatatta aaagaagaaa gaactttgga agacccattt ataatggttg
    20521 gtggtccttg tgcttataat tccgaaccat tagcagattt tgtagatgta gtaatattag
    20581 gtgaaggtga agaggttaat ttagaagtag taaatgagta taaagaatgg aagaaaaata
    20641 aaacgactag agaagatttt ttatataaaa tatctagcat agaaggagta tacataccaa
    20701 gtttttatga tgtcaagtac aatgaagatg gtacagttca aagtgtaact cctaatagag
    20761 aagggattac taaaaatcct actaaaagga taataaaaga tgttgagact gtagattatc
    20821 cagaaaaact aatagtacct tatatagata ctgttcatga tagaatagta ctagaattat
    20881 ttagaggatg tactagagga tgtagattct gtcaagcagg tatgatatac aggccaataa
    20941 gagaaaagag tgttaaaaga cttaaagaaa tattagataa attagttaag aatactggat
    21001 atgatgaaat atcattatca tcacttagta cgagtgatta tagtaagtta tcagagttga
    21061 ctgattattt ggtagatgaa tatgcatcta ataatattgg gatttcgctt ccatccctta
    21121 gattagataa tttttcaatg gaaattgctg ataaaataca acaagtaaga aaatctggac
    21181 ttacttttgc tccagaagca ggaactcaaa gacttagaga tgttataaat aaaggtgtta
    21241 cagaagaaga tttggaaaat gcaacagaaa gagcttttga gatggggtgg aatagtgtta
    21301 agttgtattt tatgattggt ttaccaactg agacttatga agatttagat ggtatagcta
    21361 aattggctta taaagttatt gatatttata gaaaagtaaa tggaggaaag ctaaagagaa
    21421 gttttagtgt tacagtgagt acttctacat ttgtaccaaa gccatttaca cctttccaat
    21481 ggcatggtca agatactaca gaagaagtta ttaataagca gagacattta gtaaataaat
    21541 taagaaataa caatataaaa tacaattatc atgattcaaa gactagtttg atggaagcag
    21601 tagtagctag aggcgataga agaataggaa aagttatata tgatgcattt agactaggtg
    21661 ctaaatttga tggatgggca gaacatttta atttagatat atggaaagaa gctatggaaa
    21721 agaataatct ttctatagat ttttatgcac atagaaatag aaactatgaa gaggtatttc
    21781 cttgggacca tatagatgta ggtattagta aaaaattctt aattagagaa gacgaaaatg
    21841 ctaaaaaaga aaaaatcact tctgattgta gacataactg caatggttgt ggaataaata
    21901 tacatgatat aggaaggggg ctttgctaat atgagtaaga taataagagt aaaatttaaa
    21961 aaggaaggcg acatgatata tatatcacat cttgaccttc agagattgtt acaaagagcg
    22021 tttagaagag ctgaaataaa cttatcacat tctcaaggat ttaatcctca ccctaaaatg
    22081 agttatggca atgctttggc tttaggggca gaaagtcaag gtgagtatgt agatattgaa
    22141 atagaagaag atgatttatc agtagaggaa tttttaaata aagtatcaat tcaacttcca
    22201 gatgggatag attttatcaa agcaaaagaa attgatagac aaacaccttc tctttcttct
    22261 gtgatagact atggagaata tttgtttaat atagatttga aaagacctat gacgaaagag
    22321 tttgtaaaaa gaaaagtaat tgactttatg aataataaag aaataatcat aacaaaaaag
    22381 aataaaaaag gtaagatggt tgaagtagat ataagaccta tgataagaac ctttgatgtt
    22441 ttaaatttag aagatgaaca tattactctt actgctacta tagctacagg ctcaaaaact
    22501 aatttaaata ctaatatact tataccaaag atattagaga tgtttgaact tgatattgac
    22561 ccattagatg ttgatatatt gagaagagat ttatatgtat tagaagatgg ggaattagtg
    22621 actcctatgt aagctcgaga ggtgaagttg tgaaaaagat agttattgag tccctaatag
    22681 ggtcccagaa aacagcagta cttgaagatg aaagattaac agaacttttt gttgaagaca
    22741 atttaaataa gaagactgta tccaatatat atcgtggaat cgtaaaaaaa gttataccag
    22801 gaatagaagc ttgttttgta gatattggat ttaagaaact tgcttattta caattaaaaa
    22861 agggaagtac tataaaatct ggtcaggata ttttggttca gataaataaa gaagaaatag
    22921 gaactaaagg cgcaaaatta aacactgaga ttagtatttc tggaaggtat attgtctata
    22981 taccttccaa tgatagaact acaatatcaa ataaaattac tgatgaaaaa gaacgattta
    23041 gattaaaaaa aattactaag gcagtaaata aggaaaatct aggattaata ataaggactg
    23101 aggctcaagg ttgcactcat gatgaaataa agaaagatat agaagagttg aaattaaagt
    23161 atgaaaacat tttaaaagaa tataaacttg gtataggtcc gaaattatta tataagtctt
    23221 tagattttgc aactaaatat gtaaaagata atgtgaatga tgatattgaa tctataatta
    23281 ccaatagtta tgataagtac tctgaactta agtctatttt aagaggtata gataagactt
    23341 atgttgataa actgtgtctt gaggaaaata gagatgtatt tgatttatac agaatagaat
    23401 ctaaaataga aaaattatta aataaaaaag tatggttaaa gagtggaggt tatttaataa
    23461 ttgaaaaaac agaagctctt acggttatag atgtaaatac gggtaagttt attggaactg
    23521 gtaaacttga tgaaaccgtt tataaaacta atcttgaagc tgcaaaagaa attgtaagac
    23581 agcttagaat tagagacata gctgggataa taataatcga ttttattgat atgcataaaa
    23641 agaagcatca aaaggagatt ttacacatcc tagaagaaga atttaataaa gataaaagaa
    23701 aagctgaagt attaggtatg acaaaacttg gtttagtaga agttgctagg cgtagagaaa
    23761 aagaatccat tgataagtat tatttaatgt cttgtccatg ttgtgatggt gaacaaacaa
    23821 taaaatctgt acattatata ctagatagta ttgaaaaaga aattatgaga ataagtgaac
    23881 atactgttta caaaaacata atggtagaat ttaatgattt tatttttgaa caaataaaag
    23941 aatattatat ggatataatt gataaaattg gtgaaaaata taatataaag atttctttaa
    24001 acgcaaatag tacattaaag cacaataaaa ccaatgttat tttcgataaa atagttgaca
    24061 ataaaatgta aatattttat aattaataat tgtaatgccg cacagtaaag gtttaaatct
    24121 tcaaatgaag taccttgtac tggcgagttt gaggccgagg aggtgtattt aatgtacgct
    24181 atagtaaaga ctggtggaaa gcaatataaa gtttctgaag gtgatgtatt attcgttgaa
    24241 aaattagaag ctaacgcagg tgatgttgtt actttaaacg aagtattagc ttgctctaaa
    24301 gatggagaat taaaattagg ttctccagta gtagaaggag catctgttca agctaaagtt
    24361 gttgaacaag gtaaagctaa gaaagttata gttttcaagt ataaagcaaa aaaagattac
    24421 agaagaaaac aaggacatcg tcaatcatac actaagatag ttgtagaaaa aataaacgct
    24481 tagttattgg ttaagttatg ataaaagtta aatattatta taatgatgat ttcttgttgc
    24541 aaggtttttg tttaaaggga catgctgatt ttgctgaaat aggctatgat atagtatgtg
    24601 ctgcagttac atctaatgct attgcagtta taaattcttt agacaaatta cagaagattg
    24661 aatttgaaaa agtagtagga gaagaaggtc atatagagtg tatagtcaaa gatacacatg
    24721 taaaagacgc acaattatta ctaaatcact ttcaattagc ggttaaagaa attaaacggg
    24781 aatacccaaa aaatataaaa attttaaaaa agtagggggt gactccatat gttaaacatg
    24841 aatttacaat tattagcatc taaaaaaggg gtaggttctt ctaaaaatgg tagagattct
    24901 atatctaaaa gattaggtgt taagagattc gatggtcaat tagtaactgc tggaagtata
    24961 atagttagac aaagaggaac taaaatacat ccaggaacta atgttggaaa aggtagtgat
    25021 gatactttat ttgcattagt tgatggtact gttaaattcg aaagaaaaga caagaagaga
    25081 aaaaaagtta gtatatatcc agtagcaata gctgagtaat atacataaaa ggagtgttga
    25141 ggcactcctt tttcttataa tactgatgaa tttataatgg tatttttggt aatgctaatt
    25201 aaaagttttt aattaagtag gtgaagaatt tgtttataga taaggcaaga atatttgtta
    25261 aggctggaaa tggtggaaat ggttcggtag catttagaag agaaaaatac gttccagctg
    25321 gtggtccaga cggtggagat ggtggtcgtg gagcaagcat catatttgaa gttgatttgg
    25381 ggcttagaac tctaatggac tttaagtacc agaaaaaata tcaagctcaa aatggtggcg
    25441 acggaagcaa aggaaaaaga gctggtaaaa atggagaaaa tttagtatta aaagtaccag
    25501 caggtacagt aataagagat gaggctacag gtcttgtatt agcagattta aaaaaagaag
    25561 gagatacagc tatagttgca aaaggtggta taggtggtaa aggtaaccaa cactttgcaa
    25621 atgcagtaag acaagctcca gcttttgcaa aatctggtac agatggagaa gaaagatgga
    25681 taactcttga acttaaaatg atagcagatg ttggtctttt aggatttcca aatgtaggta
    25741 aatcaacatt tctatcagtt gtaactaaag ctaaacccaa aattgcaaac tatcatttta
    25801 caacacttac accaaatcta ggtgttgttc aaactaagtt tggagatagt tttgtacttg
    25861 cagatatacc tggaattata gagggtgctt ctgaaggcat aggattaggt catgagttct
    25921 taagacatgt tgagagaaca aaggtattga tacatattgt agatatatct ggattagagg
    25981 gaagagaccc tattgaagat tttgacaaga taaatgatga gcttaaattg tacaatgaaa
    26041 agctttcaaa gagaccacaa gttgtagttg caaataaatt tgatatatta gaagatgaga
    26101 gtaagtttga gaagtttaag agtgaattag aaggcagagg atatacagta tttaaaatgt
    26161 cagcagcaac tcgtcaaggc atagatgaag taatagccta tgtttctaaa atgctaaaag
    26221 aagtagaaga tgtggagcta gtttcagaag aagaaatgta tagaccagaa cttgatattg
    26281 gtactgaaga agagttaagt atagatattg aagatggtgt gtatgtagtt acaggtaaag
    26341 cacttagaag aataatgtat tctgtaaatt ttgatgatat ggaatccctt caatatttcc
    26401 aaaaagctat ggagagtcaa ggtgtttttg ataggcttag agaaatggga atagaagatg
    26461 gagatgtggt taaaatttat gaattagaat ttgagtttta caattaattt aaatatagat
    26521 tatagataat ttaagtatag aattatagag gtgagaatat gttaaaagga aaacaaaggg
    26581 cgtatttaag atctttggca aatactttaa agcctactac acaaattggt aaagaaggtg
    26641 ttacagagag tttcttagag caattagatg gtatgttaag aactagagaa ttagtaaaag
    26701 ttactatatt agaaaatgca ggtcttgata ctaaagaaac tgctaatgca gtatgtgaag
    26761 ctttaagagc tgaatttgtg caggctattg gttttaaatt tactatttac aagaggaata
    26821 ttgaagagcc taaaatactt tttccaggac atgaacaggc gaaagcaaag actaaaaata
    26881 ataatgttac aaaaaagggt aaaccaacta aaagagctgt tagataatag tttatatcct
    26941 tttagggaaa taagttaaaa aaatagtgac aattggaaga aattgtatta tactattaaa
    27001 cataaattta aattagcaat cttatcaaga gtggcagagg gactggccct gtgaagcccg
    27061 gcaaccagta tatttaatta tacattggtg ctaaatcctg cagcatttat gctgaaagat
    27121 gagtataaac ccgtcatatg gcttgagttt atactcaagc tttttttatt ggtatattta
    27181 tatatataaa taatttaata taatcaaaat gatgggggta tgttacagtg aagatagcaa
    27241 tattagggta tggaacagta ggaagtggat taattgattt aatagaaaat aatacttcaa
    27301 aaagagatat agaagttgtt ggaattttag ttaaaaataa agaaaaacac aagtataaga
    27361 agtattttga taagataact actgatatag aagatatatt tgacaaggat attgatatac
    27421 tagttgaagt aattggagga ttaaatccag cttttgatta tgtaacaaga gcgttaaata
    27481 aaaaaataca tgtagtgaca gctaataaag atttactggc tgaaaaaggt agtgacctta
    27541 tagaattagc taacttaaat aatgttagca tcaagtttga agcatctgtg gcaggtggta
    27601 ttccagtttt aaaaccattg atagaatcac tggaaggcaa caatataaag agcataaacg
    27661 ctattttaaa tgggacttgt aattttatat tatcaaagat gtatgatgaa aatttaccgt
    27721 atgatgtcgc tttaaaacag gcacaagagt tgggatttgc agaagttaat ccagatgcag
    27781 atgttttagg atatgatagt gctagaaagt tatctatatt gtctacttta tcttatggaa
    27841 aaatagtata ttggaaagat ttattattag aaggaataac ttcaatagat gaaaaagata
    27901 tagaatatgc aaaaaaatta aattgtaaga taaaattggt tgctagaagt aagtatgaat
    27961 caggagaagt aagtggattt gttagaccag cattagtgga caataataat atgctttcaa
    28021 agatagataa tgagttcaac gtagttattt tagtaggtga ttcagtaggt gaactttctt
    28081 ttgtaggtaa gggagctgga agaggtgcaa caggaagtgc tgtttatgca gatattatag
    28141 atataataga taatagaagt tcaaatataa agtctttttc aaaagggaaa ttggatttaa
    28201 gtggacttat agaagatgag tgtagtgcag tagttagatt tggtgggtat aataataaag
    28261 atggaatttt agaatgttta gataaatatg tagatagtta tgatattata gatgatgaag
    28321 aattggcgat ttttgtaagt gcaaagtcag aacatgagat tgatagagtt ttggaaattg
    28381 taaaaagaaa taattacagt gaatcagcta aaaaattatt gaagatagat taatatgttt
    28441 atgcaagaat tatgaaaatt taatagggtg tctcaaaata gagagataag ccttttttcc
    28501 agtgttgaaa taataaaaat atatttgatt ttataaaaaa agagtgtctc atgaactaaa
    28561 aagttcattt tgagacactc ttttttaata tctggtgaat taataagata atagaaaaat
    28621 gtatacgtta taattaacca ataaagaaat tttcactagc ttcattaata gcttgctgag
    28681 ttacccttat atatcgctgt gtagtggcta cagagctgtg atttaaaagt tctttaacca
    28741 actctaaatt attgttactc ttttcaaatt gagtagtagc atagagcttt ctaaagctat
    28801 gtgtacttat attatacaga tttaagtatt tacaaattat cctcaactgt ttttgaatag
    28861 cctttgtctt tatatttact aagtagtcat ttgatttaag attatacttt cttgcatgtt
    28921 catttatgga ctcaattata tttttattaa ctggtctata ctgtaatttg cccgtctttt
    28981 tttcatttat ttccaacata ttacctttaa aattacctat ctttaatctt aaaatatctg
    29041 atattcttag acctaaatta gcttctaaca ttagtgccaa tgcaacttta ggattttttc
    29101 taaatctttt ttcaacgcca ttttcactat aagtaaagcc agtatgtaat agttccatta
    29161 tctttttata ttcgtctatt tctataggtc ttgttgccat tttcaaccac tcctcttagt
    29221 ttgatttggt aagtttaggt cggtatttat tatataatat aaatgaaata ttatataatg
    29281 gaaaaatttc ccagtaaact tatacaagtg tgatatatgt gattaaggag aattttttga
    29341 aaaatatttc taataaaatt attaaattgt gatgaaataa ctatgctgtt aaactaatta
    29401 aaaaggttat taaaattatg acaaatataa t
//
LOCUS       DAYAKB010000044        28481 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.044, whole genome shotgun sequence.
ACCESSION   DAYAKB010000044 DAYAKB010000000
VERSION     DAYAKB010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.044"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            36..1562
                     /locus_tag="ACGI3L_002335"
     CDS             36..1562
                     /locus_tag="ACGI3L_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9198036.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1590..2147
                     /locus_tag="ACGI3L_002336"
     CDS             1590..2147
                     /locus_tag="ACGI3L_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198037.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            2669..3706
                     /locus_tag="ACGI3L_002337"
     CDS             2669..3706
                     /locus_tag="ACGI3L_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198038.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNQILTKVVNDDNEIEEKIIEEDLLISENTIKLDDKEAIINDKNIELCKKEVQVE
                     SEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAINL
                     YTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKSEW
                     SYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYDEY
                     FKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTKVG
                     RNFIRYSLRSI"
     gene            3817..4959
                     /locus_tag="ACGI3L_002338"
     CDS             3817..4959
                     /locus_tag="ACGI3L_002338"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9198039.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            5413..6804
                     /locus_tag="ACGI3L_002339"
     CDS             5413..6804
                     /locus_tag="ACGI3L_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFG9198040.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            7057..8850
                     /locus_tag="ACGI3L_002340"
     CDS             7057..8850
                     /locus_tag="ACGI3L_002340"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFG9198041.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIAPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(8931..10313)
                     /locus_tag="ACGI3L_002341"
     CDS             complement(8931..10313)
                     /locus_tag="ACGI3L_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFG9198042.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            10571..10918
                     /locus_tag="ACGI3L_002342"
     CDS             10571..10918
                     /locus_tag="ACGI3L_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9198043.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            10936..11970
                     /locus_tag="ACGI3L_002343"
     CDS             10936..11970
                     /locus_tag="ACGI3L_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6398 domain-containing protein"
                     /protein_id="HFG9198044.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(12019..13068)
                     /locus_tag="ACGI3L_002344"
     CDS             complement(12019..13068)
                     /locus_tag="ACGI3L_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFG9198045.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            13343..14878
                     /locus_tag="ACGI3L_002345"
     CDS             13343..14878
                     /locus_tag="ACGI3L_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198046.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(15063..15749)
                     /locus_tag="ACGI3L_002346"
     CDS             complement(15063..15749)
                     /locus_tag="ACGI3L_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HFG9198047.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            15874..17256
                     /locus_tag="ACGI3L_002347"
     CDS             15874..17256
                     /locus_tag="ACGI3L_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9198048.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            17658..18926
                     /gene="eam"
                     /locus_tag="ACGI3L_002348"
     CDS             17658..18926
                     /gene="eam"
                     /locus_tag="ACGI3L_002348"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016869 - intramolecular aminotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006536 - glutamate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HFG9198049.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDTCDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(19019..19375)
                     /locus_tag="ACGI3L_002349"
     CDS             complement(19019..19375)
                     /locus_tag="ACGI3L_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198050.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(19526..20620)
                     /locus_tag="ACGI3L_002350"
     CDS             complement(19526..20620)
                     /locus_tag="ACGI3L_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9198051.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            21084..21905
                     /locus_tag="ACGI3L_002351"
     CDS             21084..21905
                     /locus_tag="ACGI3L_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9198052.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            21926..23122
                     /locus_tag="ACGI3L_002352"
     CDS             21926..23122
                     /locus_tag="ACGI3L_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFG9198053.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSISYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            23289..26687
                     /gene="cspBA"
                     /locus_tag="ACGI3L_002353"
     CDS             23289..26687
                     /gene="cspBA"
                     /locus_tag="ACGI3L_002353"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional germination protease/germinant
                     receptor pseudoprotease CspBA"
                     /protein_id="HFG9198054.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            26697..28370
                     /gene="cspC"
                     /locus_tag="ACGI3L_002354"
     CDS             26697..28370
                     /gene="cspC"
                     /locus_tag="ACGI3L_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid germinant receptor pseudoprotease
                     CspC"
                     /protein_id="HFG9198055.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLEPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
BASE COUNT        11193 a         3221 c         4882 g         9185 t
ORIGIN      
        1 actattacta tttaatatgt aaaggagtat tttaaatgaa tgaatcatat tggtttttaa
       61 actcaagtcc aaaagaatat aacaaattag gtgaaaatat aaaaacagat tgtcttatag
      121 taggtggtgg aataacggga ttgacaactg catatttatt agcaaaagaa ggtaaaaaag
      181 tagtgcttgt tgaggctgat aaaataggat atggaacttc tggaaggaat actggtaagg
      241 taacttgtca gcatgatata ttttactcta agatagagaa aaaatatgga ttagataaag
      301 caaaatcata ttataatgca aataatgaag ctttaaattt agttgaacaa ataatagaag
      361 aaaacaatat aaaatgtgat tttaaaaggg aaacttcttt tgtatttaca gaaaaagagg
      421 atactataaa ggatattaaa gatgaatatc gtacatgtaa aaaaatagga ataaattgtg
      481 agtatcatga aactatagaa aatattccat tagatataaa gggggctatt agttttacta
      541 atcaaggtca atttaaccca aagaagtata ttgatggatt ggcaaaagca gcagtaaatt
      601 tagggctaaa aatatatgaa aatacaccag tagtagacct tgaaaaagga aaaatatgta
      661 gggttaaaac aagagaggat aatataatag aagctgagaa tgttataatt tcatctcata
      721 gtccatggta tgatggattg aatttttatt ttgcaaaaga atatgcagag cgtgcttatt
      781 taatggttgc agttttggaa aataaattag cagatggtat gtttataagt atagatgacc
      841 catcaataac ttttagacaa tataatgatg gaagtgaaaa tttactgatt tttggaggag
      901 gagaccataa agttggtcag ggaggaactg agaaagaaat atttgatgat ttagagcatt
      961 atggtaaaga agtctttaag gtaaaagatt ttaaggggaa atggtctgct caagataata
     1021 tgagttttga caatgttcct tatattggtt atatcaacaa aagagaagac aatatttatg
     1081 tagctacagg gttctctaaa tggggaatta ctaatggaac tgctgctgga ataataataa
     1141 aagatttaat aataaataat aattctgatt ataaagatac ttttaatcca tccagactag
     1201 gtagctactt ttcaaaagat tttataaagg aaaatgcaaa cgtagcaata aattatgtaa
     1261 gtggaaaatt aaaaataggt agtggagata tgcctaaaaa taatggagaa ggaaagattg
     1321 ttaatattga tggaaaaaga tatggtgtat ataaggatga taatggagat ttttatattg
     1381 tagacactac atgtactcat ttaggatgtg aacttaattt taacagtgaa gaaaaaacat
     1441 gggactgtcc atgtcatggt tctagatttg actataaggg aaatatactt gaaggaccag
     1501 ctcttaagcc attaaaactt tatggacatg gtgataatga tgttaatcct aagttattat
     1561 aaaattattt ttaggaaggt aaagtgtata tgaataaact tttaaagcca ataactatac
     1621 tattgtatat agtttatatt ttatctgccg tattttttgt agcaaacaaa gaatatggaa
     1681 gtctaggtct agtagcaatt agtttagttg gtactttcat tttgagtttt ataaataagc
     1741 aaactgaaag attattgagt aaagaattat atataatgct tgctttattt ataatgtttt
     1801 catcattgtt aggtacttgt tttaattttt atgatataaa ttattatgat gattttttgc
     1861 atttatggtc aggtataata tcttgtattg tggctttttc tataattaaa tacttttata
     1921 cacaaagaga gataagtaaa atgagtaaag tgtttttagt tatattttta tttatgttta
     1981 gtatgggagt agcgagttta tgggaaatag gtgaattttt aatggatact tttgttggga
     2041 ctactacaca ggccggaggg ttagaagata ctatgattga tatggtagat gctttaatag
     2101 gcacaattat aactattcct tttatagtaa aaaaatctaa tatatagttt taaatttttt
     2161 atattaatta taatggattt aattaatcat gttgagtttc aaggtctata tgattaatta
     2221 aatccatttt tgttatttat aattattatt gaatatattt ttacatataa gatataaggt
     2281 gatagataga aattgttgga ttatgtaaat aattaatata taataccatt atgggcaata
     2341 aatacaaatc aaatgataat atagtctatt tatgtaaatg ttatattgta tcctaagtat
     2401 aatagtaagt tttttgatag tggtgtagaa agtaaaaatc tactagccta aattgatgta
     2461 tggattagtt taggaacagt aattgcatat cttaagtttg atgtcatgtt gggctactag
     2521 aaataggtca tctttttcac ttgaatatct tttctttaaa catggggagt atcatatcaa
     2581 aaacatatga aaattaagtg atttatgaga acagtaatat tttatatgat agtatagaat
     2641 agtaataaag tattaggagg aacattgagt gttaaaaaag tggtttggta ttgtgaaaaa
     2701 aagacaaaaa agtgagtcag taaaagaaga aggtgaagta atattaaaaa acgaaaaaat
     2761 attatctgaa gaaaagttga tagatgaaga aggagttgta gttaatattg ataatcaaat
     2821 attaactaaa gtagtaaatg atgacaatga aatagaagaa aaaataatag aagaagattt
     2881 gttaattagt gaaaatacca taaaattaga tgataaagaa gcaattatta atgataaaaa
     2941 catagaatta tgtaaaaaag aagttcaagt tgaaagtgaa aaaataggtt taaataagtt
     3001 tgaaggactg gaccaaaatg aaaattataa tctagaaaaa aatgttattg aagaaaaaaa
     3061 agtaagtgaa tgtttgacag aagaagattt agagtacata aaagaaatta aaataaaaag
     3121 aggaaaaagt ataaaagcta taaacttgta tactaaagaa gagtgggttt ttgacactca
     3181 tatacagtgt agtaaaaaac tcaaagttcc attagggtac ataagagaaa atttaaaata
     3241 tggatatatg gattactttg gagatgcaat aaattattta agtgaagtat taaatataga
     3301 tgaatactgc aaaagtgaat ggagctatct cgataatagc aaatctccat ctgagatatt
     3361 taatattcta aacaataaaa tatttagtat aaggctttct aatgaaaaaa gaaatgaaat
     3421 tttgacaaat gataaaattg aagcattaaa aatgaattat agatttgaat gtattgatga
     3481 agaatatgat gaatatttta aaaaatataa gtctataatc aaaagaggtg gaaagaaaaa
     3541 agttgaatta gtaaataaaa aaggtgacat tttagaaata tttaagtctt tagaagaatg
     3601 tgccatttat ttgcaaaagg aaaagaatga agttatacaa atgttaaaat atggagatac
     3661 aaaagtagga agaaacttta taaggtatag tttgagaagt atttaatttc attttaaatt
     3721 cataagagtt tcatttctga ttcacacatt taatattatt ttaatgtaaa ataataaagg
     3781 tgaagtattg cacaattaaa attaaggagg gtattaatgt ctgaagaaaa aaatccaaaa
     3841 gaaaatacat tagatgaatc taaaaattca gataatgtaa attctaaaaa agatgatgtg
     3901 tcagatgaaa aaaatactga taacaaagtt aaaaaaaggg aaataaagct aaacaacaaa
     3961 acacttaaag ctattgtagc aattgttgca gtaggagcta tatgtttagg tggaggctat
     4021 gtttttggca aagaagctgg aagaaaattg cctgctactt caaaacacta taatagcagt
     4081 gaggtagtag ctactattgg ggataaaaaa ataacaggtg aaatgttaag aaagagaatg
     4141 gagccattat tttatttaaa tgcaaaaact actatgactg atgacgaaat acgttcatat
     4201 gaatcaaata tgattgaaac tatgattaca tctgatatat tatcctctga agcagcaaaa
     4261 gagaaaataa gtataactaa tgaccaacta gatgctcagt ataataattt aatgagtagt
     4321 atagaatcag caatgggaat gactaaagaa gagtttttaa aacagtttga tttgactgaa
     4381 aaatatataa aagatgatat gaaaaaagag ctagtagcat caaaatattt aaatgaaaaa
     4441 tcaaaagtta ctgataaaga agcagagaac tattacaata aaaacaagag caattattta
     4501 caagttagag cttcacatat tttaataaaa actgttgatg ataaaggtaa gcaagttagt
     4561 agtagcaaaa aagctgaact taagaaagaa gctgaagaaa tacttaaaaa agcccaagct
     4621 ggggaagatt ttgctactct agctaaaaaa tactctgaag atagtagtgc agaatcaggt
     4681 ggagatttag gtttctttgg taaaggtcag atggtggaat cttttgaaaa agcagccttt
     4741 gcattgaaga agggagaggt atctaacaaa cttgtagaaa gtgattatgg atatcatata
     4801 attaagaaaa ctgatgaaaa atatcagcca tttgaagagg taaaatcaga tttagtaagc
     4861 agtttaacat cagaaaaaca aaacctactt atacaaaatc taaaagaaaa atataatgtt
     4921 aaaattacag ataaatatca aatgaaagct aaagaataga taaagtcaat ttattaaaaa
     4981 aaagaaaaat taactgtatg gataaaagct atttttactc tcaatataga gagtataaaa
     5041 tagcttttat tattttgcaa taaaatctat ttatatatat gaagtgataa agaaataaca
     5101 tgcaaaaagg tattaaaaag aaatattttt aatttgaatt ttttcaataa aaatttacaa
     5161 aaatgaaaaa ataaacaaaa aagaattgaa gatttaagtt gttatttaaa tatatatata
     5221 ttaagatttt ctgctgaaga tactaaaaaa ataatatttt tcataatttt aaaaataata
     5281 ataaaaaaat gaaaatacag gctataatct attgagtaaa catagaaaag atgatattat
     5341 aagtatgtgc taaaatggtt aaagcaatat taatattaaa tttaactata aaacaaaagg
     5401 gggcgttttt ttatgtcaag tacagaaagc gtatctaaaa aaagtggtca tccgaagagt
     5461 ttttggctta tttgcatgac aattttgtgg gaaagattta gttattatgg tttaacagct
     5521 ttattggtat tattttttac agcaagtgta gctcaaggtg gtttaggtct ttctactcaa
     5581 gaagcaacat ctatgtttgg cttatttaca ggtcttatat atcttacacc attagtcggt
     5641 ggctggttag cagataaagt tttaggtcaa caaaaatgta tttctatagg tgcactttta
     5701 atagcaatag gagatttcgt actatttgct tcatctacat ctattgcaat ggtttgggta
     5761 ggtctatcaa taattatttt aggaaatggt ttttttaaat caagttgctc aaatatagtt
     5821 ggggatatat atcctaaaac tgatgtgtca agaaaagatg cagcatacag tttattctat
     5881 atggcagtaa atgtaggagc atttatagct ccaataatat gtggattgct ttctgataat
     5941 gtatttgcag taagaggagc aagtggagat atagtatctt atggatataa gatggcattt
     6001 ttaatttgtg gtataggcat gatgttaggt atgattatat ttacacttct tgcaccaaaa
     6061 ttattaaatg aagtcggaaa atatcctgtg actaaaggta ataaaggtga aaaaattgag
     6121 tatggaccac ttactaagtt ggagaaaaat aggataatag caatggttat tttattttta
     6181 tttgtggtct tattctggac agcatactat caaacacaaa gttcttttat gatttatgta
     6241 agggataatg taaatagaac tctatttgga tttgaaatgc cagtagcatg gcttacatca
     6301 ctaaatgcta tattatgtgt ggctttatgc ccagtattag ctaccctatg ggttaaatta
     6361 tctcatacca aaagaggtga tttctctatt ccagttaaaa tgggattagg aatgataata
     6421 atgggtgttg ggtttatagt tatggtattt gctacattag ctaatggtcc agatggaatg
     6481 gtaaaggcta gtatattgtt tatagtattg acttatatat ttacaacagt aggtgaatta
     6541 ttcctatctc ctataggact tgcaatgttc aataaattag ctccagctaa gtatgctacg
     6601 ttgtctatgg gagcctggta tctaacaagt ttttttgcaa gtttattatc aggaaagatt
     6661 gctggtttta cagccacact tggtttttta cagatatttg gaggaatagc aacagtttta
     6721 ataatatttg gtttaatatt attgggaata agaaatgtat taacaagatt aatggctatg
     6781 gatttactaa caaaagaaaa ataattcatg acgaattatt gtaaataaat gaattacttt
     6841 aaataaagga agttacattt aaatataaaa ttaaatgtaa tttcctcttt gattatgaaa
     6901 aaaagcttta cacaaataga tattataatt aaaattataa ttgtgataat tagagtgtat
     6961 aagatttata taaattatac aaaaaatatt tatgtaataa actttacata cttatatatt
     7021 tagttattca aactattatt tcgaggaggt cttgttgtga atataaaaga tagattaagt
     7081 ggattaagaa aatttatgga agaaaaaaat atagatgcct atatgattcc atcttctgat
     7141 aatcaccaaa gtgaatatgt aggagattac ttcaaatcaa gagaatttat atcagggttt
     7201 aatggttcag cagggacggt tattgtgact aaagacgaag ctgggttatg gacagatgga
     7261 agatatttta tacaggcaga atctcaatta gaaggaagta caataaaatt attcaaaatg
     7321 ggacaagaag gttgcccaac tacagatgaa tatttatata aaaatattcc tgaaggagga
     7381 actttaggat ttgatggtag agttatatct gctagagaag gagctacatt agctgaaaaa
     7441 ttatctaaaa aaggtataaa gatagaatat cagtatgatt taatagatag tatatggcca
     7501 gatagacctg ctttatcaga tagtaaagca tttttattag atgttaaata ttgtggagaa
     7561 agttttagct caaaattagc tagattaaga gaaaaaatga gtgaaaaagg tacttctact
     7621 catgtaataa ctactcttga tgatatagca tggttattca atataagagg tggagatgtt
     7681 aaatataatc cagttgtact ttcttatgca gtaataactt taaaagaagt ttatctattt
     7741 gttgatgaaa gtaagttaaa tgaagaaata ctaaatgaac tagctaagga aaatgttcaa
     7801 ataaagccat ataatgatgt gtatgaattt gtaaaaaata tagacaaaac tgaaaaagtt
     7861 ttattagatg gaactaagct tagttataca atttacaata atataccttg tgaagttgag
     7921 aaagttgatg agttcaatcc agtaatgttt tttaaagctc aaaaaaatga ggtagaatta
     7981 gaaaatataa gaaattcaca tgtaaaagat ggtgtagctt tcactaaatt tatgtactgg
     8041 ttaaagaaaa atgtaggtaa gatggaaatc actgaaataa gtgctactca aaaattagag
     8101 gacttaagaa gagagcaaga aggtttcttt gagccaagtt tcaatacaat tgctgcatat
     8161 aaagagcatg ctgcaatgat gcactatagt gcaactccag agtcaaatta taaattagag
     8221 gcagaaggat tatttttagt agattcaggt ggacaatatt atgatggaac tactgatata
     8281 actaggacta cagttttagg acctataagt gatgaattaa aactacactt tacttctgta
     8341 gcaagaggaa tgataaatct ttctaaggct aagttcttgc atggttgtag aggatataac
     8401 ttagacatac tatctagaag ttgcatgtgg aatatgggaa ttgattatca atgtggaact
     8461 ggacatggta taggatttgt gctaaatgtt cacgaagctc caaatggatt tagatggaga
     8521 gtagtacctg aaagatttga tagtgcagtt cttgaagaag gaatggtaac tactaatgaa
     8581 ccaggtatat atatagaagg ttctcatggt ataagaacag agaatgaaat tgtagttaga
     8641 aaagctgaaa agaatttcta tggtcaattt atggaatttg aagttgttac gttagctcct
     8701 attgacttag atggtatagc accagaatta atgaataagg atgaaaaaga ttatttaaat
     8761 tggtatcata agttagttta tgataaaata tcacctttct taactgatga agaaagagaa
     8821 tggttaaaag tttacactag agctatatag tttgtactag atacaataaa aatcgaggta
     8881 ttataatgcc tcgatttttt attgtatatt ttattaactt taaaaaattt ttaatttgat
     8941 aattctacta attttttatt cattataagt agtataattc caaatatcaa taaaaatgat
     9001 ggtatcacta tgaagacttg taacatacca agttggtcta taatagcttg cgtatagcca
     9061 gataatttat ttgctgcaaa tttgcctaaa aaccaaacac ccattaggaa tgaaatatac
     9121 ttttcaggcg aaagtttatt taccatacca tacccgactg gagaaaagca aatttctcct
     9181 atactttgga atgttaaaaa tccaactacc caaaatacac ttgctttgtg aattgaatta
     9241 gggtctgttc ctgtttgtat aactgctact atcataaaca aaaatgctat ggctaatagt
     9301 ataaaaccta agctcatttt ttttggcaca cttaaatcgc cttttttagt ttgagataat
     9361 tttacccata ctaaagcaga gataggtcca agaataacac aaaggagacc attgtatgaa
     9421 tctatccatg aagtaggaat ttgaaaattg ccaacagtaa gatttatgtg ttcctttgta
     9481 tagagtgcaa tagacataga ggcttggtta tatgctatcc aaaaaaatac tgtgaaaaaa
     9541 gctaacacca atattactat tattcttttt ttctcaatca aagttaaagg tcttgaagcg
     9601 agcattttct tatattctag tgattttctt atagactctc tcccgttaat agggtcatta
     9661 ttcaaaggtt tataaaactt tctgtttcca aatataaaga agaataaacc tattagaacc
     9721 gtaattgatg aaaataaaaa tacatatcta tatccataca tacttataga taatccgctt
     9781 ttcatagcaa accattcatt agcaactaaa ccgcatatta aagggccaaa taaagtacct
     9841 agattagtag ccatatacgt aatagagaaa gctccatctt ttcttgggtc atcattggta
     9901 tataagtttc caaccatagt atgtaagttt cctttataaa aacctattcc taatccagat
     9961 aaaaatatca tgatgtttat atccatctta ctatttgcta tgtatcctag aaaataacca
    10021 attgaaacca ttagcattcc aagtataata cagtttttgg gacctaaaaa tctatcactg
    10081 acccatccac caataactgg agagaaataa gtccatgcta aaaaagatgc aagcattgat
    10141 gcggattctg ctggtgttaa ccctaaacca cctttggaga cttgttcagc taaaaacaat
    10201 aataatacca atttcatacc atagtatgca agtcctacaa aggtaaatat tgaacagcag
    10261 aaatataaat ctctaggttg tttaagtttt tcttgcgttt ttaaaactga catatgtcga
    10321 gaacctccag ataaatagtt taacaaaatt ttaccatact atatgagtat atgttttttt
    10381 catatagacg tcaacttgta agataattta attaagtcga aatatatgta aaaatagtat
    10441 catttttgtg tattcagtaa tattttttta tgataatata tgttattatt atattaaaat
    10501 acaaacatat ttatggaaag gatatgccaa tttagtagtt agattgattg tttggcaggt
    10561 gggatgagct atgataagaa agaaatctga attacaagta gaagtaaaag aaaatttaaa
    10621 tggtggtata ggaaaggtta agcttgaaaa cataatacaa aatgaagagc ttaaaggaaa
    10681 aggaagacta tttaaaagag tagctttacc agtaggaagt tcaattggtg tgcatgacca
    10741 tacaacagat tttgaagtat attatatact aaagggaaaa ggtaaagtat ttgataatgg
    10801 ggaatttgta gaagtaaatg agggtgatgt agtgtataca gctgatggcg aaaaacattc
    10861 tatagaaaat ataggagaag aagatcttga gtttgtagca ctagttttat atatgtaaaa
    10921 tatggaggag gagtcatgac aggcaagata gaagaaatta aggacaagat aaatagattt
    10981 tgcaactcca atttaaatca agaatacaaa gatataagct ttaaaatttt gcaaaacctt
    11041 ttagataata ataaagagat aattcattct tctagagctg atatatggtc ttcagctata
    11101 ctaaatatag ttttagaaca aaatctttta tacaataaga agcatccact acatataaca
    11161 aaaaaagagt tttcaaaaca aataggtgtt tctttaaata ctataaataa taaatcgtct
    11221 ttaataaaag atgtttgtag tattgacttt ttaaatcaag atactatagc tatttctaat
    11281 gtagaatttt gggtaaaaga gactaattcc aaatcaaagt ctgtagattt agatttagaa
    11341 aagaagaaaa tactatataa aagatatatt aagctatcac aagatgcgaa tagtgatatt
    11401 gaatcaatta gatatatgga ggaagctgta aatataggta aaagtatgat tactaaagaa
    11461 gataaagaac ttggattttg gaaaggttta tctaccagag cctatatgat agcacttgaa
    11521 tcccttgcta gaaagttaga aagtattaat aatctaaagg agtccaaaaa agtattagaa
    11581 tatttaatag aaattaatcc tagtgatgag cagggaataa gatacaaatt attaaatgta
    11641 ttaattagat taaatgatag aacttcaata aataaattat ttgaacttta taaagaagaa
    11701 aaatctgcta catggatgta cagtaaagct ctttattact ttaaaaataa aagtatgttt
    11761 ttggcaaatg attctattaa ggttgctaga agtaaaaata agtacgttgg attatatttg
    11821 ttagattggc gaaatgcttt tggtagagaa tttgttacag aggaagaaaa ggcagaagct
    11881 gtctattact atgatgaaaa catagtgatt tggaatgaag ttaaaggttc tatggattgg
    11941 ctattaaaaa aaatgttgga attttcataa aaaaaactac tccttacttt tatataagtc
    12001 aaaggagtag tttttaattt atacatctag ttttaaatct tcaggtttta ttagaccttt
    12061 ttttctcata aattctgaaa tcaacaaagt tacaatagca ggaagtataa aattaagtaa
    12121 aagtatacca acccacatag atatacctcc ttttccagca ctttgcatag cagttactgt
    12181 tccaaattgt ccaaccaatc cacaagtacc cataccagaa ccaataggaa tattctccat
    12241 tttgaatatt gttgtagata atggtccaag taatattgaa gctacagtag gtggtatcca
    12301 aattttccaa ttttttatta tattaggtac ttgcaacata gatgtcccaa gaccttgtgc
    12361 cacaaggcca ccaactccat tttctctaaa gctcataaca gcaaagccta ccatttggca
    12421 acaacaacct acagttgctg caccaccagc aagaccacct aaacttaaca tcatacaaat
    12481 agctgcacta cttataggta atgtaagagc tattccaaca agtgcagaga ctaaagctcc
    12541 cattattata ggttgcatag ttgtagcttg cattattata tttccaaatg aagtcataaa
    12601 agcagaaaca gctggaccaa taagttcagc tacaagtact ccaattagta ttgttacagc
    12661 aggtgtaacc aatatatcta tttttgtttc ttttgaaact aattttccaa cctctacagc
    12721 aaaaagtgta gcgacaaatg ctccaacagg tcctcctaat tcattaccac aagctccaac
    12781 aagtgcacaa gaaaatagta caagtggagg tgcttgaagt ccatacgcaa tagccactgc
    12841 tatagctgga ccagtaacct gtttagcaag agggcttata acttcagtaa aaagagaaat
    12901 attgaaatta tctcctaatg tattgaaaat tgttccaatt aaaagggacg aaaaaagacc
    12961 gagtgccata taacttagtg cgtcaataag atacctttga acagaaattt caatattttt
    13021 tcttttagca aatgatttga aatttctttt tttataattg atttccaatt taaaatcctc
    13081 ctcatataat ataagtataa tttcttttta attaattata taacttttca gctgacaaga
    13141 caaatgttat ttcactaaaa ttagactatt gtaatagtaa gaaattaaca ttaattttag
    13201 ttttaaattt taaatttatg gtttataatt agtataggga tattctgaaa tataataatt
    13261 ttccagttta tcccaatatt taacttaggt agattgctta caaaacaaat gattatatat
    13321 taggctaaaa ggaagtggat agatgatatt tgtaaaaaat aagaaataca gaaaaattgc
    13381 cataattata tctattccta tattgcttgt tgcgcagtac taccttttta aatttggaat
    13441 acttagacca atggtaaagg gagtagaaat tgaaattgta gatggggaat atgttaaaga
    13501 tatagataaa tatgtagtaa aattaaatga aacagttact ttgtctacag gtgaatatat
    13561 taaggttcct tcgtatgcta aaaatccaaa tatttggttt aatgtattgg ataactcagg
    13621 gactttaaaa atagatggaa ataaaatgac agcattaaag gttgggtatt cttctgtggg
    13681 tatcatgaaa aattcaagag tattaaaaaa ggctactata aaagtagtag acccagaggt
    13741 agaatcacta gatatggaga ttaatgggga tttaaaacat gttggtgata gtgctactat
    13801 agaaagtaca atagaagttg attatgataa gtttaaaaaa tcatataagc cagtttataa
    13861 gagtagcaat gaaaatattt taaaaatcaa aggaaataaa gtaagtgcag ttggagttgg
    13921 taaagctaca atatatgcta agtgtggaaa taaagaaatt gagagaacat ttaggattca
    13981 agctagagtt gctgaaataa atatggatga tataaaaata gaagttgacc agaatgaaaa
    14041 attgaaacca gatataataa cttctccgcc tggtttagaa ccaccaaaaa tatattatga
    14101 gttagtagat tcaaaattac ctgtagaaag agcaataagt ttaagtagta atggaaatgt
    14161 tgtagggctt agagaaggta aagatagggt gagaataact tgtggagata aatctaaagt
    14221 aataacagta acagtagtca aagaaactat aacgaatgac tatatacaaa acttggttgg
    14281 ttcacataaa atagtaaaca ataaagttat tattaaactt gaatgggatt atatgaaaga
    14341 tgtctttgat tatgatatat atcttaaaga taagttgtca ggagaatcat ttaagaaaat
    14401 taaatctata actataaatg aaagtgattt aggtaagtct aacaaggtat atgcaactat
    14461 agaagtagat atgaagggta atcaaaatat agattttgat atttatgtca tagggaaaaa
    14521 ggattcagat acaactaagc caagtaatgt aataaatatt accaatggaa atggaaattc
    14581 aaataatgat aataatatta aagatatgag ggtagaaaat atatcagcta atgttgatag
    14641 agataataat gtcattagag ttaactggag tagtatatct cataaggact gtacttacag
    14701 tatatatgta aaaaataata ctaatggaga tggagaattt actctatatc aaagtgatat
    14761 acagggaaat gagcatacta taagtattcc tgaaggagat ttaaatctag atatttatgt
    14821 tgttgcaaat tataatggaa atagctctca aaatagtgat gttataaatg taagatagat
    14881 ttgtatacaa attgaaagtg ttgagtttat ttaaatatta aattaagaaa aaggatagta
    14941 tagggtaatt atactatcct tttttgttac aatatatagg tttaaaatct ctagtaatat
    15001 aaattataaa aagtcttatt tacacaaatc tatagatatt ttttttatta atcaatattg
    15061 tcttaaattg aacttagtgc ggcttctatt gcatgtatta ctgtcgtatc aaatagtgga
    15121 atagaagtgt cattttgttt aattaaaaga cctatttctg tacatcctaa tataacagcc
    15181 tctgcacctt gtttgccaag cttatctata atagataaga aagctttttt tgaagattca
    15241 gatataattc ctaagcaaag ttcattaaat attgtgtcat ttactattat acggtcttct
    15301 tcatttggaa ttaagacttc aattccatta ttaataatta catttttata aaaatcttgt
    15361 tccattgtat atttagtacc taataaggcc acttttttta tttctttttc ccttaatacc
    15421 gtagcagtta catctgctat gtgaagtaat ggaatatgta tactttcttg tattttatct
    15481 gataccttat gcatagtatt agtacagata acaataaaat ctgcccctgc ctcttgtaat
    15541 ttaattgcag catcagctaa aattttggcg cttttttccc aatttccact agattggcat
    15601 tcttcaattt cttgaaaatc tacactgtaa agtatacatt tagaagagtg tagtccacct
    15661 aatctttctt ttattactgt attaataact tgataatatg taatggtact ttcccaactc
    15721 ataccaccaa ttaagcctat agtcttcata ttatacctct cttatttatt tattttgaaa
    15781 tagctattta caaatacaag tatagcatct aaaatagaag catacaatga taaaattgta
    15841 tggagtacaa ttataattaa gaggagtaat tatatgccaa taaattcttt tgaaaactat
    15901 cctatgacat ggaaaccaaa attagataac cgaaaaccac caatatataa aactttagca
    15961 atgttattag aagaagatat taaaagagga aatttaaatc ctggagataa actgcctcca
    16021 caacgggaat tagcagattt tctagattta aacttaagta caataacacg agcatttaaa
    16081 ctttgcgaag aaaagggact aatatgtgca aaagtgggaa agggaacatt catttcttct
    16141 gatgtaaatg taagtaatac attattatat caaacggaat caaaagacat aattgaatta
    16201 gggacagttc atcctccgta tgagcaaaat acatatatta ttgactttat taaaaatgta
    16261 ctaaaacaac cagaaatgga taggttttta caatacatgt ctccatctgg cacatatatg
    16321 caaaaaaagt caattgcaaa atggatagaa agaaataatg tatacaccag tgaagaaaat
    16381 atattattat ctacaggagg gcaaaatgct atatgtgcaa ctttactagg attatttaaa
    16441 gctggtgata gaattgctac agattcttta agtttttctg gaattaagtc aatagctaaa
    16501 atgataggta ttcaattagt cccaattcct caagaaaata atgaaatatc gattgaatat
    16561 cttgaaagtt attgtaaaaa tgaaaatata aaaggcatat atcttatacc agattatcat
    16621 aatccaacga cacatactat gtctgattta tctcgtaaaa agatagccaa gatagcaaag
    16681 caatataata taataattat tgaagatgct ataaatagca tttttagaga tggtatacaa
    16741 actcccatat tttctttagc tagtgataat actatatata tttttagtac atctaaattt
    16801 ttatgtgctg gtcttagagt agcatttgta gttgctccaa aacgatatat agaaaattta
    16861 gaaaatgcac tatataatat gaatctaatg gtttctccat ttacagcaga aatagtacac
    16921 cgtttattat attctcctat tatagataaa attatagaag agaaaagaga tgcaattata
    16981 gaaagaaatg aagttgctga taaagttttg tcagattata atttgattgg tgataagaat
    17041 tgcagttttc gttggttact tcttcctgat gaattggatg gaaaatcatt tgaaatttct
    17101 gcaaaaaatc taggagttca agtatattgt gctgaacgat tttcagtagg aaactctaca
    17161 gttccaaaag cagttcgtat ttgtgtaaca gctccaaaag atgtagaaga attagaaaaa
    17221 gggcttaata taataaagtc acttcttaag agttaaattt attttactat tatttaatta
    17281 aataaataaa aaggcggaga aatttattat aataaacctc cgcttttatt atttaatgaa
    17341 atactttact ttttattaaa aaatttaatt ttaataatct tgaaaatata atcgttttat
    17401 ggtaaaataa ttcttaaaaa tagaaaaaat taatcatttg ttaaaaaaaa tgcataattt
    17461 attgtaattt attgacgaag gttgaaaaat attcataaat gtgcgaaata acagaaaaaa
    17521 tgcaaaaatt aattcaattt catttgttat aaaatctata tggcaaaatt aaatctgcct
    17581 atcagaatga tataaacaca ccagaaagga ggacgctatc aaataataca agtagttaac
    17641 tttgatagca aaaaattatg aatgaacaaa ctagaatatc cttagagaga gctgctgaat
    17701 taaaatcaaa aattgatgat tatattcagg ctagaaaaac gattaacaga ggtcttgaaa
    17761 aagaagaaga gataaataaa cgaaaacaga aaatattaag tatcttaaat ggaactgaag
    17821 aggattggaa taactacaaa tggcaattat caaatagaat aacagatgta gatactttat
    17881 caaaaattat aactctaact aaaaaagaaa aagaatatat aaaagaggtt ggtactcaat
    17941 ttagatgggc aatatctcca tattatttga gtcttataga cccagaagat acatgtgacc
    18001 caataaaatt actgtctata ccaacacata tagagttgga agatgaacaa gaagatttgg
    18061 acccaatggg agaagagtat acaaacccag caggatgtat aactagaaga tacccggata
    18121 gattaataat aaatgtaaca aatgagtgtg ctatgtattg tagacactgt cagagaagaa
    18181 gaaatattgg acaacaagat tctcataagt caaaagctat tatccaagaa tctatagact
    18241 atatcagaga aaatgaagaa ataagagatg tactagtaac tggtggagat gctcttacat
    18301 taaaagatga ttatttagag tggattctta gccaacttaa agagatacca catgttgatt
    18361 atgttagatt aggtactagg actcttgtta caatgccaca aagaatcaca gatgaatttt
    18421 gcaatatgct aaaaaaatat caccctgtat atataaatac tcattttaat catccaatgg
    18481 aaataactaa ggaatctaaa gaagcttgtg aaaagttagc aaatgcagga gttccattag
    18541 gaaatcaggc agtattatta aatggaataa ataatgataa atttgtaatg agatgtttaa
    18601 atcaagaatt actgaaaata agagtaaaac cttattatat attccaaagt aaacatgtaa
    18661 agggaacaaa acatttcaat acatcagtag atgatggtct tgaaatcatg gagtatttaa
    18721 gaggatatac atcaggaatg gctataccaa catatatagt aaatgctcca aaaggaggcg
    18781 gaaagactcc tttgcttcct caataccttg tatcaaaagg aacagattac gttatgctta
    18841 gaacatggga aggaaaagtt ataaaaatgg aagatgaacc tgctgtagat ataaagaaac
    18901 ttataaaaga acaagcgcag gattaaaaaa gtatttaaag tttataaaaa gaaacaactt
    18961 taaaataaaa agaaaatgga tgtcaaattt atatcaattt gcatccattt tttattagtt
    19021 atttattatt ttgttgttga ttaactaatt caagatatcc acttgggtgg aagtaatata
    19081 tctcagaagt attttcattt acaaagtaac caatatcacc atctgcatct ggtaaaaata
    19141 cataaccatt aagattttta gcttttaatg cttcaaaatc actagcattt ccttgatata
    19201 tgtaatcaac ttcattgttg tattttacta aaagttcttt agcttgttct tgagtcaatt
    19261 tagtattttg gcttacagga acattctttt gagaatctgc ataagaagat tcatttactg
    19321 gtgcagttaa taacaaacaa gataaaacta ataaagatat aagtgctttt ttcatactaa
    19381 aaccctcttt catgtttaat tatataagat tcattactta ataatattgt atgtttccta
    19441 taattaaata ttaccattaa agagaataat attacagtta cacagctgta acttttgatt
    19501 acaaaatcgt aattaaattg tatttttatt ccatttgtat tttatcatgt ctacgattta
    19561 caaactcaca gaagtatatc tttataacgc ccatcacagg agcagataga atcataccag
    19621 gtataccaaa gaatcctcca ccaacagtaa ctgctaggat tgtaaagaat gggctaagac
    19681 ctagttgtcc acctacgatt tttggctcta taaatgtaac ttcaacttgt tgaattatta
    19741 ttaagtaaat taaagaagtt aaagcaattg ttggattgga gaataaatta attattacaa
    19801 ctggtgccat acctattact ggaccaaaat atggaaccat attcatgaca cccataagtg
    19861 taccaaataa tagtgcatat tcagatttta aaaagtaaag accaattcca gaaagtactc
    19921 caactataaa agaatctaaa atcttacctg taaagtattt accaatattt aaatttaagc
    19981 tttgacatag ttctattata aagtctccat attttttacc taaggaaata taaactactt
    20041 tttttgtaaa cagtaagaat ttttcttttt ctaataatat atagaaacaa attataaaac
    20101 ctaaaagaaa ttgtactata aattttccaa ctgaaaatgt agtgctaaat atcccaccaa
    20161 gtgaaccaat aagcaagtta ctaaatttag gcattacact cataattttg tcaccatact
    20221 cttttaatgt attagggtca actgattgta aactcttgcc taagtcgaat aaaaactgct
    20281 ctgttttatc tatgtatgta ggaatttgag caactaaatc agctaaacta tttactatgg
    20341 atggaactgt aaataatata aacgaaatta gtataactat gagtacacca taagtaagaa
    20401 gtaacgaata tattctctta aaatttaatt tactttctaa gaactttact agtgggttga
    20461 atatatatgc taatacaaat gctattataa atggtgttag tagtgacatt aataaactta
    20521 tcactccaaa aaaatatttg taattatcaa taactttaat caagatatat gaaacaacta
    20581 cagtgagtac aatatttaga taaatttttt tatcttgcaa aataacacaa cctttcttat
    20641 atttattaaa tttagatata cttaaatcta agttaaagtt aatatttata gcttattata
    20701 caataaaaag cagtattaat atagtatgat taatatgaaa ttataaatac gttaaaactt
    20761 tatgtttata gctaaaataa taaaaattat ttatattgtg tttatatata atctaaaatg
    20821 aaaaaaagtg gtgcctttga ttaaactaag tttttataat ttaaattttg tacaataagc
    20881 tatcttttat tattctttaa aatatatatt tcatttaatt atgacaaata aagataaaaa
    20941 ttaaatattt tagaggtgat tttatttaga tatagaattt tagaataata ctatacaaat
    21001 gtattgtatt attattttta tatcaaaaat agtaataaag tctatataca tttagaaaat
    21061 actgtttaaa aggagtagga tttatgataa aaaaagagat atctaacttt agaggaagta
    21121 gtgattatgt agtatcacca gaattgatgg catcagttaa tgttgctatt gctcttgaaa
    21181 agccactttt gattaagggc gaacctggaa caggtaaaac tatgctagca caagcaattt
    21241 caaatgaatt aaaaaaagat ttagtaattt ggaatataaa atcaactaca aaagcacaag
    21301 aagggcttta tgtatatgat actgttcaaa gactttatga tagccaattt ggaggagaag
    21361 gtgtagatga tattagcaag tacataaaat atggtaaact aggagaggcc tttagctcaa
    21421 atcaacaagt aattctttta atagatgaaa tagataaggc ggatttagaa tttccaaatg
    21481 acttgctttg ggaattggat aaaatggagt tttacataaa tgagacaaaa gaaactgtaa
    21541 gagctaaaca aagaccaata gttattataa cttcaaatgc ggaaaaagaa cttccagatg
    21601 cttttttaag aagatgcata tttcattata tagaatttcc tgatagagac atgatggaag
    21661 aaatagttaa agtacatttt gataaagtag aagaacacct attggaacaa gtaatgacta
    21721 ctttttattg gattagaagt ttaaaggaca tacaaaaaaa gcctagtaca tcagagttaa
    21781 tagactggat acaagcatta actttgagtg gaatgcctat tgaaaaaata gaaaaagaag
    21841 ttccttttgc aggaatacta cttaagaata atgaggatat tgaatctatg caaagacact
    21901 tatagttaat aggagctgga taattatgtt tattgaattt ttttatttat tgaggtcaag
    21961 aggattaaat gtatctttaa atgaatggat gactttaatt gaagcattgg ataaaggact
    22021 gtgctattca aacttttcaa atttttacta tctttgcagg atgattttaa taaaaagtga
    22081 aagtgatttt gataagtttg atgcagtgtt tttggagtat tttaaaggta tagaacacca
    22141 agaagaaatt ccagaagaga ttatgaattg gcttaaaaaa ccagatatag atttagaaga
    22201 gtttgaaaga ttagaacaaa atccaaatat aaatcttgat aaattaagag ctaaattgga
    22261 ggaacgaata aaagaacaag attctcctca taatggtggt aattattgga taggcacagg
    22321 aggcacttca gagttaggac attcaggaaa agggcaaact ggtatacgta taggtggaaa
    22381 ttctacttat ggtagagctg ttcttgaagt tgcaggagaa agaaaataca gagattttag
    22441 agatgatgaa gttttaaata tgcgtcaatt tcaagttgca ctaaagagac ttcgtcaatt
    22501 ttctactaga atagatgctc caaagacaga gcttgatttg gataagacta ttgaagagac
    22561 ttgtaataat gcaggatatt taaagttatt ttttgagaag ccaagaaaaa atacagtgaa
    22621 gcttttattg cttatggatt caggtggttc aatgagaggg tatagcactt tatgtaatac
    22681 attatttcag tctgtaagta aatcaaatca ttttaaagat gtaaagatat attatttcca
    22741 taactgtatt tatgatagat tatttacaac acctgaatgt tggttaagta aatctattaa
    22801 tactgaatgg atattaaaaa atatagataa aaactataaa gttataattg ttggagatgc
    22861 ttctatgtcg ccttctgagt tgcttcatat tggtggtaac tatcgtggtc catataatta
    22921 tacacctggt atagagtggc ttaaaaggtt taagagaaag tacagtaaaa ttgtatggat
    22981 gaatccagaa cttagagatg gatgggattc aattagttat tggtatcaaa ctcaaagaat
    23041 gatacaaagt gaatttaata tgtttccatt gactgtaaaa ggtcttgaga aagcattgaa
    23101 aaatttaatg gtttcaagat aaagtaaata taaatgatgg tatgatttat tcaaaattgt
    23161 accatcatta tttatttttt taatatatct attataaatt gtataactga aacttaaaaa
    23221 attatatagt ctaatacatt ttagactcac acaaaacata tacattaata ataattttag
    23281 aagtcgaggt gattataata aattatgaat taattgtaaa atacaatgga gatatattga
    23341 ggttagaaga agaattaggt gtatcagtag agatacttaa ttcatcatat gcaataataa
    23401 catcaagtaa tgaagaagat gtaaatatac ttttaactta tccagaaatt gaatttatag
    23461 aaaagccttt tatattacag actcaggatg tgcaaagttt ttcaagtaca ggaataacag
    23521 gatttaaaaa tagaactggt ttaactggaa aaggaactat aattggtata attgattcgg
    23581 gaatagatta tactctacct gtgtttagag atagtgatgg aaggtctaag atattatatt
    23641 attgggacca atctattcaa ggaaatccac cagaaggttt tagagaagga acattatata
    23701 ctaatgaaga tataaataat gcaatagatg gaagtatgta tatacctatt tcaacaacta
    23761 gcttacatgg aacacatgtt gcaggtattt gtgcaactat tgcaagtgat gccagaataa
    23821 tagtggttag agttggaaat atacagaccg atattttttc gagaagtaca gagtttatga
    23881 gggcaattaa atttatttta gatagggcat tagaattaag aatgcctgtt acattaaata
    23941 taagttatgg aagtaatgaa ggttcacata gaggaacatc tttatttgaa caatatatag
    24001 atgatatgtg tttattttgg aaaaacaata tagttgtagc agctggaaat aatgcagata
    24061 aaggaggtca taaaaggatt aggcttcaaa ataatattac agaagaagtt gagtttatag
    24121 ttggggaagg agagcgtata ttaaacataa atatatggcc agattttgtt gatgatttta
    24181 gtgtacattt ggtaaaccca tcaaataatc aaacacaagc aatctctcta acttcaggtg
    24241 agataaggaa tactttgggt gaaactagaa taactggtta tttttaccct atagcaccgt
    24301 attctctcac aagaagagtt actctacaat taagttcaaa tacacagata actcctgggt
    24361 tatggaaaat tgtatttgaa ccaatagata tagtaactgg taatgtaaat atatatttgc
    24421 caacttctga aggtctaaat agaaatacta gatttctgat tcctactcaa gagcttactg
    24481 taacagttcc tggaacagca agtagagtta taacagtagg tagttttaat tcaagaacag
    24541 atatagtatc tatattttct ggtgaaggag atacacaatt aggtgttttt aaacctgatt
    24601 tattagctcc aggtgaagat atagtatctt ttttaccagg aggtacaagt ggagcattaa
    24661 ctggaactag catggctaca cctcatgtta caggggtttg ttcattgttt atggaatggg
    24721 gaattgtaaa tggaaatgat ttatttttgt attcacagaa attaagggca ttacttctaa
    24781 agggagcaag gagattaagt aatcaatctt atccaaataa ttcatcagga tttggttttt
    24841 taaatttatc agatatagat ttgtacactc tatctaatat aaatcaagat ttagaaacag
    24901 aggatattgg atatagaagt attaataagt catttaaaga tgaggaaaat agttataagt
    24961 ttatagatgg ttataatatg caaatacata atgacttaga gaatgaaatt tatataagta
    25021 aaaatgcaag tagacaatca ggaatactat caggaataga tatagtccat actcctgaat
    25081 ttgaagaaga actagctggg ttaggtatga gtcaaaggtt ttttaagata agtgattcat
    25141 taggtgtact atctataaat aatacagact ataatagcat acaacgagtt ttgcaacttc
    25201 cttcaatcat aagaactgta tcgactacaa agatgacatt acttggagaa attaatcgag
    25261 gtacttttgg aggtgtagtt gcaacagaag aaatgggcgt aaatttcttt aaaaataatc
    25321 ctaatattaa tataacagga agagggactc taatatcaat tgcagataca ggaatagact
    25381 atctacaccc agattttatt tatccagatg gcacttcaaa aatagtatat ttatgggacc
    25441 aaacaaaaga aggaactcct cctgatggtt tttatattgg gacagaatat acacgagaag
    25501 atataaatcg agctatcgca gaaaatgacc ctagtctatc tcaggatgaa gttggtcaag
    25561 gaactatgtt gagtgggata tgtgcagggc ttggaaatgt aaatagtgaa tatgcaggta
    25621 tagcagaaga ttctgagcta ataataataa aactcggcaa gatagatgat ttttataata
    25681 gtgcaatgtt gtttgctgca tctcagtatg catataaaaa agcttttgaa cttggaagac
    25741 cattagttat aaatatgtct ttaggtacca gtagcctagc aggtttaacc aataggagta
    25801 atagtgaaaa agcgttcttt actagagggt tatgtataac ggcaggagca ggaaatgagg
    25861 gcaatacaca gacacataca tctggaataa taccatatgt tggaggttct gttgaagttg
    25921 aattagagtt aaatgaagac gaggaagaat tatcattaga actttggtta aatagaccag
    25981 ataaagctga tgtaataata gtatctccca ctggtgaaga aagtaaaagt gttggaattt
    26041 caaattataa taaagtaaca ggtttatttg atttagaggg gactgaatat tctataacat
    26101 atatataccc aacaactttt tctggacagc aatttactaa tgttacttta aagaatgcaa
    26161 aaagaggtgt atggaagatt cgattagtag gagtttatat tataacagga agatataact
    26221 tataccttcc aaatagagaa cttttaaaaa gtggaactag atttagagag gtagaccctt
    26281 tttacactat aaattatcct gcgattcaag atgatttaat aaccatagga gcctacaata
    26341 ccattaatgg tagtttatgg caaagttcat caagagggcc aactattgaa gacaggttaa
    26401 aaccagatat agtagcacca ggtgtcaata taatagctgc ttatcctggg aacacgtatg
    26461 caactataac tggtacagca gcagcaagtg cacatgcagc tggtgctgct gcaatgtatt
    26521 ttcaatatac ttttgttgac ggtagatatc caaaccaagc atatgtgcaa aaaataaaaa
    26581 cttttatgca agctggtgct agaaaagatt caaacacagt atatccaaat acaaattctg
    26641 gatatgggct cttggatgtt agaggaatgt ttgatgtttt aagataggag ggatttatgg
    26701 aaaaatctta ttgtataatt tatcaaggtg atatagaatc tgccctacaa gaaaatggaa
    26761 taaataggta tatggtttta aatagtcagc ttgcagtaat atatgtacct ttagattttg
    26821 atgaaactat tttaaataat ataatacaag ttgcttggtg ggaagaatct gaaccaatga
    26881 gcagtctaat tgaaataact aataatgtaa ataatggaga aaccattaca acagcagctg
    26941 aaactgatta tatttatgaa aatccatata atgatataac agggagagga attttattag
    27001 cagttataga ttctgggata gattatttgc atcctgattt tataaatgat gatggaacta
    27061 gtaaagtttt atatttatgg gaccaagaag caaatacaaa tccacctcca gaaggtttta
    27121 tttttggaag tgaatttaca agaagtgagt taaatatagc cataaataga aatgatggga
    27181 gtttgagtca agataatata ggtactggaa ctttagtttc tggtatatta gttggaaatg
    27241 gaaggataaa ttctcagtac agaggtatta ctacagaatc agacttaata gtagttaaat
    27301 taaaatcata tacagatact tattatgctg gaaggataaa ttacagtgtt tcagattttt
    27361 tagcagctat aacgtatgtt actaacatag caagaacaga aaataaacca ctgataataa
    27421 atttgactat tggagttaag tcaagtgctg tagcaactac ttcaatacta gatactttta
    27481 atatattgag tagtgctggt gtggtagtag tgagtggtgc aggaaatcaa gggaatacag
    27541 atattcatta ttctggcaga tttagcagtg tgggagaagt tcaagatgta ataatacaag
    27601 atggagatga ctatgctctt gatataacac taaatacgaa tggtccagat aaagtgggag
    27661 cacagataat atctccttca ggtgaagtta gtcatgatat aaggtattct ccagactttt
    27721 atatatatag aggaaaattt aacttagaaa atactactta tgcaatgaga tttatttatc
    27781 catatattac ctctggaaaa gaaaatttgg agataagatt aagagatata aaacctggag
    27841 tatggatttt aagattgact tcagaactta taataaatgg agaatatgac atatacttgc
    27901 caaataaaaa tttgatagct ccagacacaa ggtttttaga gcctgattca gtagctacta
    27961 taactatgta tgctgctagt gatgatgtaa ttacagttgg tacatttaac aataagactg
    28021 atagtatgtg gattggttct tcgaaaggac caattagagg aagaggaatt aagccagata
    28081 tagtagcttc aggtgtagat ataatatcca catataaaaa tggaacatat aatacaggaa
    28141 caggaacagg agtgagcagt tctatagtca caggtgtttt agccttattg atggaatact
    28201 tagaaaaaca ggataatgta ccgagattat cattgtttac acaagtttta aaaacatatt
    28261 taatattggg tgctacaaaa cttgagatat atacatatcc aaatgtatcg cagggatatg
    28321 ggattttaaa tttaaaaaat acgattcaac agatagcaaa tactctatag ataagaacct
    28381 atgtaaaatt ataattgatt attagtttaa ttgtatcaaa tactttagat agagtagaaa
    28441 aatagcataa aaaataaata tgaaaattaa aaaacagttt t
//
LOCUS       DAYAKB010000045        27652 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.045, whole genome shotgun sequence.
ACCESSION   DAYAKB010000045 DAYAKB010000000
VERSION     DAYAKB010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27652
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.045"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            210..1031
                     /locus_tag="ACGI3L_002355"
     CDS             210..1031
                     /locus_tag="ACGI3L_002355"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9198056.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    1110..1321
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1408..2724
                     /gene="argH"
                     /locus_tag="ACGI3L_002356"
     CDS             1408..2724
                     /gene="argH"
                     /locus_tag="ACGI3L_002356"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HFG9198057.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELQKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            2973..3311
                     /locus_tag="ACGI3L_002357"
     CDS             2973..3311
                     /locus_tag="ACGI3L_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HFG9198058.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGKP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(3438..4727)
                     /locus_tag="ACGI3L_002358"
     CDS             complement(3438..4727)
                     /locus_tag="ACGI3L_002358"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9198059.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            4807..5511
                     /locus_tag="ACGI3L_002359"
     CDS             4807..5511
                     /locus_tag="ACGI3L_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFG9198060.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKLNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            5603..6649
                     /gene="selD"
                     /locus_tag="ACGI3L_002360"
     CDS             5603..6649
                     /gene="selD"
                     /locus_tag="ACGI3L_002360"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:5651..5653,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HFG9198061.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            6700..8079
                     /gene="selA"
                     /locus_tag="ACGI3L_002361"
     CDS             6700..8079
                     /gene="selA"
                     /locus_tag="ACGI3L_002361"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HFG9198062.1"
                     /translation="MLPSVDEVLSDNRIVEIINEYPRSLVLESVREVIDLKRQFILRL
                     KEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLGRSLLSEDIKDE
                     LWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNAAAVLLVLSTMA
                     KGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYKEAITEDTNVLM
                     KVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKYGLSYEPTVLDS
                     IRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDKLTICALEATLR
                     MYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINIEDGFSQVGGGS
                     MPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDVRTIFDDEFDVI
                     VEELRKAFN"
     gene            8193..10076
                     /gene="selB"
                     /locus_tag="ACGI3L_002362"
     CDS             8193..10076
                     /gene="selB"
                     /locus_tag="ACGI3L_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HFG9198063.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            10181..12919
                     /locus_tag="ACGI3L_002363"
     CDS             10181..12919
                     /locus_tag="ACGI3L_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HFG9198064.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEHELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(13038..13982)
                     /gene="manA"
                     /locus_tag="ACGI3L_002364"
     CDS             complement(13038..13982)
                     /gene="manA"
                     /locus_tag="ACGI3L_002364"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFG9198065.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            14155..15516
                     /locus_tag="ACGI3L_002365"
     CDS             14155..15516
                     /locus_tag="ACGI3L_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9198066.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            15604..17493
                     /locus_tag="ACGI3L_002366"
     CDS             15604..17493
                     /locus_tag="ACGI3L_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9198067.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            17508..17963
                     /locus_tag="ACGI3L_002367"
     CDS             17508..17963
                     /locus_tag="ACGI3L_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9198068.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            18022..18339
                     /locus_tag="ACGI3L_002368"
     CDS             18022..18339
                     /locus_tag="ACGI3L_002368"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: protein motif:HMM:NF014368.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFG9198069.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            18364..19626
                     /locus_tag="ACGI3L_002369"
     CDS             18364..19626
                     /locus_tag="ACGI3L_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFG9198070.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            19731..20795
                     /locus_tag="ACGI3L_002370"
     CDS             19731..20795
                     /locus_tag="ACGI3L_002370"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFG9198071.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YAGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            20849..22027
                     /locus_tag="ACGI3L_002371"
     CDS             20849..22027
                     /locus_tag="ACGI3L_002371"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9198072.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(22218..23276)
                     /locus_tag="ACGI3L_002372"
     CDS             complement(22218..23276)
                     /locus_tag="ACGI3L_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFG9198073.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            23343..23714
                     /locus_tag="ACGI3L_002373"
     CDS             23343..23714
                     /locus_tag="ACGI3L_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFG9198074.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            23751..24425
                     /locus_tag="ACGI3L_002374"
     CDS             23751..24425
                     /locus_tag="ACGI3L_002374"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFG9198075.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            24674..25513
                     /locus_tag="ACGI3L_002375"
     CDS             24674..25513
                     /locus_tag="ACGI3L_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HFG9198076.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            25757..25853
                     /locus_tag="ACGI3L_002376"
     tRNA            25757..25853
                     /locus_tag="ACGI3L_002376"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25791..25793,aa:Sec,seq:tca)
     gene            26003..26710
                     /locus_tag="ACGI3L_002377"
     CDS             26003..26710
                     /locus_tag="ACGI3L_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFG9198077.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(26852..>27652)
                     /locus_tag="ACGI3L_002378"
     CDS             complement(26852..>27652)
                     /locus_tag="ACGI3L_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HFG9198078.1"
                     /translation="ISLLIGCDKKSLLSIHMIDVGQGDSILVQTPTNKNILIDGGDED
                     SENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIYMPEQSTDSEAYQ
                     NLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNSIVFKLTFNDNSF
                     LFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKISPDIAAISCGYKN
                     QYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEIDT"
BASE COUNT        11034 a         2892 c         4772 g         8954 t
ORIGIN      
        1 ctagcattat aagactataa attgaaaata ttcagaaaaa tactacaaga aacgatttat
       61 tttgctctta aaataagtta aatgaatgtt attaattttg taaattgaaa tagtttaagt
      121 ataaagttat gatataatct aataagggta attctttaga ttatattaag gaaatatagg
      181 tatacaataa aaagttatgg agttggatta tgggatataa attaattgta acagatatgg
      241 atggaacttt attaggcaat aatcataaag ttacagatga aaataaaact gcactacaaa
      301 aagttataaa aagcggtatt aatgtaactt tagcaacagg aagagccttc gattcagcta
      361 aatgcaatgt agattttctt aaagaggaca tgccaataat agcttgtaat ggttcattaa
      421 taagagagca aaatggaaat ataatatatt caaataagat tgatacaaga acatgtttaa
      481 acattttaga tgtattagat aaatacgata tttactacca atgtaatagt atagattcta
      541 tgctttcgaa aaaaatagaa ggacgtgaag atagattaag tgtattttta ggctctgaaa
      601 cagaagtaat tgtaaaagat gatttgagag aagaaatctt taaaaaagat atactaaaat
      661 ttgtaatcat agaagaaaaa aatccatcta ttttggatga aataagaaaa gaattgagaa
      721 aagttcaagg aataaagata acctcttcat ggccaaacaa tattgaagtc atgaatgaag
      781 gtgttgataa aggtaatgca gttaaaattt tagctgaaaa aatgaatata gacagagaag
      841 atataattgc atttggagac aattacaatg acatagaaat gataaagttt gctggtcttg
      901 gggtagctat gggaaatgca gaagaattga ttaaacaaga agctgattat gttacagata
      961 caaatcaaga cagtggagtt gcaaaggcaa tttataaatt cctagagtta aaagaatcac
     1021 ttagctctta aaacagtata taataggaaa aaataggttg actattttgt agatagtaat
     1081 tataatacaa atagataaaa tataaaaatt tagattcagt gaaaaagaga gtagatatag
     1141 agaaaatctc agcgaattgg gggatggtgt gagcctaatg ataacacttt atattgaaaa
     1201 gaactttgga gaatactact tgaaattcag tatggtagta ggtaatctcg ccttaagaga
     1261 atagagtggg taaacattgt ttaccaacta gagtggtaac acggaatatt tcgtctcttg
     1321 gtctttttga ccaagagatt ttttagtttc attgagttac aagacttata attaaaatac
     1381 aaaaaattaa aatatgaggt gaaagttatg aaattatggg gtggacgctt tagaaaagcg
     1441 gaaaatcaac ttatggaaga atttaataaa tcttttggct atgattgtgt actgtacaaa
     1501 aaagatatcg aaggaagtgt agcacatgtt catatgcaag taaaatgtgg acttttaaca
     1561 gaagaagaag gaaagtctat aacagaaggt ttaaaaggga tacttgaaga tgtagaaaat
     1621 ggaaagttag tattggatgg agagtatgaa gatatacata gttttactga gataaattta
     1681 attcaaagaa ttggagatgt tggcaagaag cttcatacag cacgtagtag aaatgaccaa
     1741 gttgcagttg atatgagatt gtatgctaaa gaaaaagcaa atgatttggt ggatttaata
     1801 tctgaattta aagctactat aaaagatgtt gctgacaaaa acccagtgat gatgccaggc
     1861 tatactcatc ttcaaagggc acaagtagtg acatttaagc atcacttaat ggcatattat
     1921 agtatgtttg atagagatga gaaaagaata aaaaatgcta tagaaatatt agatgaatca
     1981 cctttaggct gtggagcttt agcaggaact acgcatgata tagatagaag tataacttgt
     2041 gaacaattag gatttaaaaa agtagtagat aattttatgg atggagtaag tgatagagat
     2101 tatttactag agctaatgag tgatttttca attataatga tgcacttaag tagattaagt
     2161 gaagagttga tactttggag ttctcaagaa tttggatttg ttgagataga tgatttatat
     2221 acaactggaa gtagtataat gcctcagaag aaaaatccag atggtgcaga gcttataaga
     2281 ggtaagactg gtagagtata tggaaactta tttggtcttt ttacagtaat gaaaggaata
     2341 ccattagcat ataataaaga catgcaagaa gataaagaag gttttttcga tagtgtacat
     2401 actcttgaaa tgtgtataca aataatggat agaatgatag ccacactaaa ggtaaatgag
     2461 gataaaatga aacaagcagt aaaaaatggt tttttaaatg caacagaagt tgcggattat
     2521 ttggttaaaa ataatgttgc ttttagagat gcacatggta tagtaggaag tatcgttata
     2581 tattgtgaag ataataaaaa agcaatagaa gatttaacat tagaagaatt acaaaagttt
     2641 tcagatgctt ttaaggaaga tatttatgat tttatcgact atgagagtat attaaataag
     2701 ggaataaaaa agaatttaaa ataatgtatt tatttttaaa agctgtaaat ttgaatgtta
     2761 tcatttaaat ttacagcttt ttattgtgta agattttatt atataaaagt aagaaactta
     2821 aaaggagtag tatttaaaat aaatacaaat aaaaaattat tattaaaatg ataattaata
     2881 tcaataagta ttgacaaaat tatttctaaa tactattata tataatataa ataataatga
     2941 aaatcaatat caaataaatg ggaggaaatc taatgaactt attagtgatt ggtggtcatg
     3001 aaagaatgga aaaagattat atggttatgg ccaagaaaaa aggttataag acaaaggtat
     3061 atactaccat gtcatctaaa ttaaataatt ctataggaaa accagatgca gttgtcatac
     3121 ttacatcaac tgtttcacat aagatgtcta gaacggttga gtctcaagct aaaaaacaag
     3181 atatattaat cgtaaggcat aaaaatagta gtaaggtagc atttaatgaa tgtctagata
     3241 tggttgatga atgtctggga aattgttcaa aatgtaagct taaagacaaa caaaaacaaa
     3301 aaaatatata ggtataaaaa atacataaac ataaaattaa aagtactgag ataatagtta
     3361 taattattat ctcagtactt ttagatttat aaggataagt atagtataaa ttttttatta
     3421 taatttccaa ctacttgtta ctttttcata ttttttttac ttctagcttt ttttcttttt
     3481 ttcttcttta tatttgaagc tattataaat aaaactaaaa gcactagaat acctgcaata
     3541 atcttaacaa aagtcattaa aacattattt tcagtcaaaa atggaagact gctatcaaga
     3601 ttattttttg caattaagtc tatactgttt tctagtttac cattattata tacatttaaa
     3661 gtaccaacct tagctccttt ttttataggc aaatcaattt tatttaactc tgttttggta
     3721 tcataattgc cttgagattc atctttttct aagaatatcc tataactatt ttttggttca
     3781 taaatcaatt catgttgttt tgtaaacaat acttttttag tatctgtgta tttttcttta
     3841 tcaacaatag tagcacactt aaagttatca aatccataat caatcagaat acgtgagtct
     3901 aaatataaat cagcattagt tgaattaaat acagcaacga taactcttct gccatctttt
     3961 acagcactcg ataaaagaca tttaccagca gcatcagtat atccagtttt tataccatca
     4021 actatatcat attttatatt tataggttga cctttgtatg taatcttatc atgtgatgtc
     4081 aaaaacttat tagtgtttac aaagtatctc tcataaggat atgcttttgt agcttcaaat
     4141 ttaagtgact tagtttttac aatttgtcta aaagtatcat tattcatagc ttctctagct
     4201 atgagagcca tatcatgagc tgttgtgtag tgatttgggt ctggtaatcc atgaggatta
     4261 ttaaaatgag tattagtagc tccaattttt tttgcctcag agttcatgag gtcaataaat
     4321 ttttgtacat tgccaccacc aacatatcta gctaatacaa aagcagcatc attagcagaa
     4381 tgaaccaaaa gagcatctag taactgcttt acagtaaaag attccccatt ttttagatac
     4441 atactagagc catctatttg aggtaaatct ttaatttcta ttacttgatt taaatcttta
     4501 acctccttta gaactaaaca agctgtccat actttagttg ttgaagctgg ataaagctta
     4561 gaatttccat ccttattata tagtattttg ccagactcat agtccattaa aactgcatgt
     4621 ttagcaacta tagctggttc attatctgca aaagagatat tagagcttcc taaaaatgaa
     4681 gtaaatatca ataaacagat taataaaagt gataaatttc ttttcattgt gagcctccaa
     4741 attttaaatt catcttttag tatagcatat atttgtcaat aattaaaaga aaggagtgat
     4801 taatatatga aaaaaaaggt aaaatttatt tcgttttttg ttttatttat tttaataata
     4861 tcatcaataa tcgtttataa atcgcttatt ttcaaagatg atatttatgt tgtaagtaaa
     4921 aaaaatttac ctaatgaaaa aacacatgtt gtagagaatg aaattaaagg tgaagataat
     4981 aatcacagta aagtaactaa agacatagat aaaaattttc aaaataataa aataactata
     5041 tacataagtg gagcagtaaa tagacctgga attgtaacta tagagtcaga caagagactt
     5101 tatgatgctg tagaattact aggaggaacg acaaaagaag cagatttaaa tggagtcaat
     5161 ctatcagtaa gattagaaga tgaacaacat tacataatac ctaaaatagg tgaagcaaca
     5221 tctgttacaa gtaatgatga ttccaataaa ctaaatcaga agaatgagtc aagaggtgag
     5281 cctaaaaata aatccaataa aaatatatct aacgaatcaa aagtaaatat aaatgtagcg
     5341 acgatagaag agttggattc tctacctggg gttggagaag ctacagccaa taaaatttta
     5401 caacacagag aagaaaatgg acagtttagt tcaattgagg aaataaaaaa tgtaaatggt
     5461 attggagata aaaagtatga aaatataaaa gatttaattt gtgtagacta aaatataata
     5521 caaaacttac atatagatat gttattataa atatgtatgt atatgtgtgt acatgtggaa
     5581 atttagtaaa ggaggcactt ttatgaaaaa agaacaaaaa aaacttacag agatgacaac
     5641 agcaggtggt tgagccgcta aaatagggcc agaggttctg gcatcagttt tatctcaatt
     5701 gcctaaaaat gataatatag aaaatttatt agtaggacta gatacagcag atgatgctgc
     5761 agtttataaa ttaaatgatg atatggcact tatccaaact ttagacttct ttacaccaat
     5821 ggtagatgac ccatacgtat ttggtcaaat tgctgcatca aattcactat cagatgtata
     5881 tgctatggga ggcaaacctt tggttgctat gaatattgtt tgttttccat catgccatga
     5941 tatggatgta cttgcagaaa tattaaaagg tgggtttgat aaagtgaaag aaagtggagc
     6001 acttttggtt ggagggcata ctgtagatga caaagagcct aaatatggtc tttcagtttc
     6061 tgggattgta agtccaaata aagttttatc aaatgctact gcaaaacctg gtgataagtt
     6121 aattataaca aaaccaattg gagtgggtgt attaaataca gccatgaaag aaggtatggt
     6181 agaacaacat atagcagata aagtaataga aataatgata catttaaata aatatgcagc
     6241 aatgagtttt gagaaatttg atgtaaattc ggttacagat ataactggtt ttggtctact
     6301 tggtcatact ttagaaatgg ccaaagcttc tgaagtaagt attgaaattg aatcaaaaca
     6361 tgtaccaatt attgaaggtg caatagaaat ggcacaaatg ggaattatac ctgctggtat
     6421 gtataaaaat atgcattatg tatctaaaga tgtagaagtt gtaggaaata tagaagttgc
     6481 agttcaagat attttatacg acccacaaac atcaggaggg ttgttaattt cagtaaaaga
     6541 agaacttgca gaggagcttg taaaagatat gaaattaaat ggagcaatag aagctaaaat
     6601 tataggttct gtagttccaa aaggggaaaa atatattaca gttttataaa atattataga
     6661 gaaagagtga ttgttttgag caaaagagaa ttgtttgcaa tgttgccttc agttgatgaa
     6721 gtattaagtg ataatagaat tgtagaaata ataaatgaat atcctagaag tttagtttta
     6781 gaatctgtga gagaagtaat agatttaaaa agacaattta tattaagatt aaaagaagat
     6841 gcatcaaact ctgtaacaat agagtttggt gaaataatag aatctgcaat agagagagtt
     6901 aagttaaatt actcattatc tttaaaaaaa gttataaatg caactggtac agttattcat
     6961 acaaatttag gaaggtcttt acttagtgaa gatataaaag atgaattatg gtgtgctgct
     7021 tcaaggtatt caaacttaga atacgatttg gataatggag aaagaggttc aagatactct
     7081 catttaacta gtacaataaa aagacttact ggagcagaag atgtactagt tgtaaataat
     7141 aatgcagcgg cagtacttct tgtacttagc acaatggcta aaggaggaga agcaattgta
     7201 tctcgtggag aattagttga agtaggtggt tcatttagga ttccaagtat aatggctctt
     7261 agtggtgcag aattagttga agttggttca actaataaaa ctcatttgaa agattacaag
     7321 gaggccatta cagaagatac aaatgtattg atgaaggttc atacaagtaa ttatagaata
     7381 atgggattca cagagagtgt ttctatagaa gaattggtta atttaggtaa aaaatataaa
     7441 ctacctgtaa tagaagactt aggaagtgga gtttttatag atttatcaaa atatggttta
     7501 tcttatgaac caactgtatt ggattctatt cgacaaggtg cagatgtagt aacttttagt
     7561 ggagataaga tgcttggagg tccgcaagca ggtattatag ttgggaaaaa agagtatata
     7621 gaaaaaatga agaaaaatca acttactaga gcacttagag ttgataagct tacaatatgt
     7681 gctcttgaag caacattgag aatgtattta gatgagacaa aagctataga aaatatacct
     7741 actttaaaaa tgttgacata taaaattgaa gaattagaag taaaagcaaa taaactattt
     7801 gaaaaaataa ctgctttaaa cttaaatgca aacataaata tagaagatgg attttcacag
     7861 gtgggaggag ggtctatgcc tcttgaaact ataagtacaa aggtaatatc aataactcct
     7921 gaacatatga atgtttcatc tttagaaaaa aaactaagac ttagtgaagc acatataata
     7981 gccagagtgt atgataataa atatgtacta gatgtaagaa ctatatttga tgatgaattt
     8041 gatgtaatag ttgaggaatt gagaaaagca tttaattaaa taaatttgag ttaataaata
     8101 ttaaatttag aagtataagt atgaagtttt gattaaaaaa tagctacaca cacttgtgac
     8161 tttagtcata gcaggtttag agggggcaaa aaatgaaaaa tgtagtaatt ggaacagcag
     8221 gtcatattga ccacggaaaa actactctta taaaagcatt gactggaaga gagactgata
     8281 cgttagatga agaaaaaaag agaggtattt caataaactt aggatttact tattttgatt
     8341 taccaaacaa tagaagagct ggaattgttg atgtcccagg acacgaaaaa tttataaaaa
     8401 acatgttagc tggagcatca ggaattgata tagttttact tgttgtagca gcagatgaag
     8461 gggttatgcc acagacagtt gagcatttag atattctaag ctttttaaat atcaaaaatg
     8521 gaatagtggt tctaactaag tctgatactg tagatgatga atttagagag ctagtaaaag
     8581 aagatatttg tgaaaaaata aaaggaactt ttcttgaaga tgctgaaata attgaagttg
     8641 attctatatc taaaagaggt atagacactc ttattgaaaa aatagataaa atgagtgatg
     8701 atatagaaga taaaaatgaa aactctccag caagacttaa tatagacaga gtattttcaa
     8761 taaaagggtt tggtactgta ataacaggca ctttaataga aggaaagata agtatagaag
     8821 atgatttggt tatatatcca caggtattaa aaacaaaaat aagaagtata caagttcatg
     8881 gagaaaataa agatacagct tatgcaggtc aaagaacagc aatcaatata tcaaatgtaa
     8941 aagtggatga tataaaaaga ggagatgttt tagctgcacc aaactcattg gaggaatcaa
     9001 tgatgttaga tgtaaaatta tcattggtaa atcatttaga taaaggatta aagcactggg
     9061 atagattaag attgtatcat ggaactagag agatactttg tagagcagtt ccactagata
     9121 aagaattaat tgaaagtgga gaaagtggct atgttcagtt gagacttgaa gaaagcatag
     9181 tatctaagaa aggtgatacg tttgtagtga gacgttattc tccaatggaa actataggtg
     9241 gaggtgtaat aattgaccca tctcctaaaa aacataagaa atttgatgaa aaagttatag
     9301 aagcattaaa aataaaagaa aaaggcgaac taaaagatat aatagaagag tacttaaaaa
     9361 ggaatttaaa aaattatcca aatataaaag aaataatgag ctatagtggt gctcatgaag
     9421 aagatgtaaa aagagcgctt gaaacactta tatcagaaga taaagtattt attataggaa
     9481 atatgtatat gcatataaat caatacaata aattaaaaga aaatacaata aagcttttaa
     9541 gtgagtacca taagaagtat aggcttagaa aagggatact aaaagaagaa gtaaggtcta
     9601 agatagagag taattttaag actagggaga tggatatttt attagaaaaa ttgtctacag
     9661 aaaatgctat aaaaatagaa aataatatag tatctctatt agattttgag gttattttaa
     9721 atgataagca aaaagaaata gcaaaaaaaa tagaaaaaag attaaaatca tgtggagttt
     9781 cttctatact gacaatagat gaagtttctg aaggaaatca taactatgct gaagtattgg
     9841 agtcaatgat aggtaataaa gtagagaaat tagatgattt gtatataatg gacaaagata
     9901 tttatgaaaa tgcaaagaac attttgataa attatataaa agaaaataaa gaaataacat
     9961 taggagaata cagagatttg attgattcta gcagaaagaa ttgcatgatt atattggaaa
    10021 acttcgatag aaacaaaata actaaaagag tagaaaacaa aagaattttg ttttagcaga
    10081 aaatgtctgt ttttgcttta aggtataaag aaggaattat aatgtcgagt atcgtataat
    10141 taattagtat aaaatattaa ttaagaggaa gtgtaaagta ttgaagaata taatacctga
    10201 tgtaaaacca gatataaaag aaagagaaga catgagcctt ttatttataa taatgggctc
    10261 agtactttta ttatttatta taaaagatat agagaaatat gaaactttat tacatgccat
    10321 atatacgata tttttagtag ctacaggagt aattatattt aatactacaa aatttaaagt
    10381 agattcattt tctacatttt taggattaat ttttatagct actggagtat tggagtgtat
    10441 atatttattt aattccttgg ggattaaaac taagtctata atggagatta acatcacaat
    10501 atcagcaata acagatttat ttcctatact gggtgtatac ttaagtttta aatttgttaa
    10561 ggataacaaa caaatttatt caagtgtaat tttatttata gcaactgcta cattaacaat
    10621 aacatcttta ttcataatat caggaatttg tgactatctg ggaaatggta aatcacaata
    10681 tgctttagga gttataatat ctatattcat aataattatt tctatcatta gtggaattga
    10741 attaaattca agttcaaata aaggtaaatg ggaatatgat gaaaaaaaga tttttaacag
    10801 aataatagta ataataatct tatcaagagt tccaaatcta ttgcatatag ttattgataa
    10861 tagaaatgta gagaggatat tatcacaaat aataataaat gtagccttat attatttata
    10921 taattacata gtatctaaga atattaagaa aacagcactg gaattgcatg atacgaatga
    10981 agaattaaca aaaaaaacgg aaagtttaaa agaaaagaat aaaaaattaa tctatgagac
    11041 agaaaagata gaggaactta agggaatact tatgaaaaga gaatctaggc tacaatctac
    11101 attagatgta gcagtaaata gcatagtagt atttagcaaa gatggagaaa ttacatatgc
    11161 aaataagagc tttagaaata cttttggaga ctataaagaa caagataaat tgactgataa
    11221 aataaaaaac ttcaatgatt tgatagaaag cattcattat gtgtttgttc atgagaagaa
    11281 tgcagagaaa cttattagta caagcgataa taaagtttat caagctatat ttgcaccttt
    11341 aattattgct tcacaaacag aaggagtatt gtgtgtacta gaagataaga ctaagaaaaa
    11401 ggagtacgaa cgcaaactta ttgaagcaaa taagagaagt aaagattttt tagaaagtat
    11461 tggagatggc atagtagtgc ttgaaggtaa taacaaaata tatgttaata atgcatgtag
    11521 ggaaattttt aaaaataatt tagagagtat tgatttttca ttagtatgta aaagtgaaga
    11581 aagtatagaa aaaagatatg taatagatgg tgaagtaaag tatgtagaga tgagtttttc
    11641 tcagtatact aatgctggta ctaataaaac tattattgta atacgtgata caacctctcg
    11701 aaaaatatct caaataaaac ttgaggaaag tcaatcatca tattcaagat ttatagatat
    11761 attacctgat ggcatatgct tattaaaaga agatttaagt ataaactatg caaataagtc
    11821 gtttttagat atgctagctt ttacaaacat agatgatata aaagattcta atattaaact
    11881 attaatgaat gcgaatactg aagaaaaaat gaaatttacg gataatatgg ctaaagtttt
    11941 aaatgaaaat agaagtatac ttttactgga acatgaattg ataaatagtt atgatgatat
    12001 agtagaagta gaattaagtg cattaccttt tgctatatac aatactagat acataatgct
    12061 tattataaaa gatttagtac ataagaaata ttccgagcaa gcagaaaaag aactgcttga
    12121 aagatttaaa acagataaaa tcaaaacgga gttttttgca aatatgtctc atgaactaaa
    12181 aactccacta aatgttatat ctagttcaaa tcaactggta gattctttct atagaaatga
    12241 aaagataaaa gattacaata acaatattaa atctcatgtg gatttagtta gacaaagttc
    12301 ttataggctt caaagattaa taaataacat tatagattta acaaagatgg agtctgggtt
    12361 ctatacacta aaacttgcga aatacaatat tgtatctgta atagaagact tatttatgaa
    12421 tatagaagag tatgcactta gaaaagacat aaaaattctt tttgatacag accttgaaga
    12481 aattaatgtt tatatagaca aggttgaaat tgagagaatt atgttgaatc tattgtcaaa
    12541 ctgtattaag tttactgata atggaggttg gatatatgta agtattcatt ataaaataga
    12601 taaagtaatc ataagtgtaa aagacactgg agttggaata ccacaagata aattagagtt
    12661 gatttttgaa gaattttcac aagttgataa gactttatcc agaaatactg aaggaagtgg
    12721 aatagggctt gctatagtta agaatctagt aagtcttcat ggtggagata tagaagtagt
    12781 aagtgaagtg aataaaggca cagagttctt aatttcactt ccaatgaagg gatttagtag
    12841 tgaacattac acagaagata agagaatata taatattcaa gaaaaaataa aaatagaatt
    12901 ttctgatata tattattaaa aatgattatg agcaaaaata aaataaaaat actatttgtt
    12961 taaatattta agttgtaaga aataggctat cataaggtaa attattatga tagcctattt
    13021 ttagctaggt tttatatcta tatgtgagaa catataatct ctaaattacc ttcaaaacta
    13081 aaatctccaa agtcgtttgg cagtataaaa tgcataccct tttttaaatt atattctaca
    13141 gaattgtgta taagttttcc atttccatcc aacacactgt ataaagaaaa aggtgtattg
    13201 tgtgtaaaat tacattttcc aaaaacatct aatttataaa cactaaaaaa ttcgtttgac
    13261 acaaatgttg tgcatttaaa gtctgatgtt gatacgattt tatagtcagt atcgaaattt
    13321 atatgaggaa cattcgtaac atctattgat ttttgaacat gaagttcacg cttattacct
    13381 gaattgtcag ttctatcata atcatagact ctataagtag tatctgagtt ttgttgagtt
    13441 tctaaaatca atgttccttt gcatatagca tgtatagtgc cacttggaac atagaaaaag
    13501 tctccctttt ttatattaac ctttctaagt agtttgtccc attcattatt atttaccata
    13561 tttacaaatt ctttatgaga ttttgcatta tgacctatta taatttctgc atcatcagaa
    13621 caatctatta cataccaaca ctctgtctta cctaactctc cattttcatt ttttttagca
    13681 tattcatcat ttggatgaac ttgaactgat aaattatcat ttgcatccaa tatttttgta
    13741 agtaaaggaa acttatcacc aggtgtgttt ccaaataatt ctctattttt attccacaat
    13801 tcagatagtt ttttaccttt atattttcca ttttctatta agcaatctcc atttttatga
    13861 gagcttatag cccaacattc accagttgtt ggcgaatcta tttcataatt aaatttatct
    13921 ttaagtgcag taccacccca tattctatcc ataaaaatag gttttaaaaa taatggttcc
    13981 ataatcctgt tcctcctatg atattaaatt tatcctacaa ataattatat ataaatagat
    14041 tataaaatca atagtaaaaa agttttgtcc cttgaaatga cataaagtat aaggagttat
    14101 taaataagat aaactatgat atataatata aagttctaaa ttggagtgat aattatggag
    14161 ttgtttaagg cagaaagcaa aaaatataaa aaagaatttt taaaattatt ggagcaatgg
    14221 gttagtatac cttcatttta tgatagaaaa actgtatcta aagacatgcc ttttggaaaa
    14281 ggagtatatg atgcattaaa ctggtttgaa aatctaggta gagaaaacaa tttcaaagta
    14341 aaaaatatag ataatcatgc tgttcaaatt gaatatggaa atggtaaaga gtatgtagat
    14401 atatttggac attgtgatgt tgtaaatcca ggtgaaggat gggatagtga accatttaaa
    14461 ctaaatatta taggtgataa attagttgct agaggtgtat ctgataataa agggcctatg
    14521 atagtgaatt ttttagcact aaaaatgata aaggatttag atattaattt aaaaagaaag
    14581 gttagattaa tagctggggg aaatgaagag agtggattta aatgtataaa gcattattat
    14641 agcaaagagc catatggtgt atgtggattt actccagatg ctaaatttcc tgtattaaat
    14701 ggagaaaaag gtggagcaat aataaagtta atttcaaata tagacgataa atctttatat
    14761 ataagtggtg gaatagagtt taatacaata ccagataaag tttatataaa gaatgtagaa
    14821 aaattgggta aagataatat atgttttgat attaacaata tatcgataaa ttatgataat
    14881 ggcaattata ttgtgtatgg aaaaggtggt cattcatcta aacccgaaaa atcaataaat
    14941 cctatattag ctacaattaa acttttgtca gaaaatattg atgaaaaatg gacaaaagat
    15001 ttatataagt tgataaatca agataatata aatggaaact tatttggttt aaatattgag
    15061 gggaaatgtg gaattttatc aatggtgcca acaataataa atatagtaga tggaaaatta
    15121 gaagtagttt taagcgttag atatccagaa atattaacca ttgaagatat aataaaaaaa
    15181 tttaatttgt atatggagca aaataatatt aataaatttg agcttattgg ggaaaattta
    15241 aagcaagcaa attatataga tagaaattca aaacttgtaa gaagtttgca tgatatatat
    15301 ataaagtatt ctggagattt aaaaaatgat gttagagtaa ctagtgcagg aagttatgct
    15361 tctgaaatga ataattcagt aatatttggt tgtgaatttc ctgatggtag ctttggcaat
    15421 gtccatagtg cgaatgaatt tgctagctta gatagattta taactgcaat aggtatatat
    15481 gcagaggcaa taattacatt atgtaataaa atataaatac aaaatgtccc ttatatagac
    15541 atattatata tacaattaaa attttacttg atatataatt gaaatcaaag agaaggtgat
    15601 acaatgataa ctaagaaaca tgcaataata gtaaagagtt taagcaataa agatggatat
    15661 atgacatcaa acgaattagc tatcaaattg gatgtgtcta ctaaaactat taaaagatat
    15721 atagcagatt taaatagtgt tttaagcaaa tatgatttgg taatagcttc ttctagaggt
    15781 ataggataca agttaagcgg ttctaaaaac aatatagcca gagctgttaa agaagcaaat
    15841 aaatatattg atggtttttt agatgactct gaagagtcaa gaatgtcaaa tataatatgt
    15901 atgcttatta atagaaatta tatgagtata gaagcaatgg cagaagaatt aaatctaagt
    15961 atagccgcta taaataaatt gtctagtaag cttaaaagaa aacttgaaaa gtatgactta
    16021 gttataaaat ctaaacctta ctatggaagc tatatacatg gtgaagaaat taatataagg
    16081 caattaatta ctgactatgc aataaaatta gatgaaaaaa gtaaagtgaa ggtgttttta
    16141 gatgacatta gtgaaaacga tatacactgt atagaaagta ttttagaaaa gcacttaaga
    16201 gaaaaagata caataatttc agataaagat tttaatcttt tgctttcaaa aataatcgtt
    16261 tctgtattta ggagtaagag aggtcatagt aacaatataa acttaatgga tacaagttat
    16321 agatttcata actactactt tatagaaaat ctaatgaaag aaatatctga taaaattgga
    16381 tttaaactta ttgaagatga agtaatttat atttcaaatt attctggtgt aatagcctat
    16441 aaaggtacac aaggaagaaa aaacacaagt gaaattgagg aacgaataag tagtgttata
    16501 agtagtgcac ttcaagatat attccttatt tcaggtagtg attatacaaa agatgatgag
    16561 tttatggttg caatctctga ccatataaag agatttttaa atagagctag agctaatgta
    16621 aaatcaaata atcctttact tcatcaaata aaagagaagt ttcctatagc ttttaattta
    16681 gccgtgtttt tatcaaataa actagaaact gagtttaatt taaaacttga tgaagatgag
    16741 cttggatata tagctatcca ctttgctgct tcaaatgaaa gaatgaaaaa aaatactagt
    16801 aagaaaattt gtatagtttg tcattatggg ataggaacag gacaacttat ttctgaaaag
    16861 ctaaaacaga atataagtga tttaagtgtt gtaggtgttt atccagttag atatctcgat
    16921 atggctataa gtcaagatgt tgatttgata gtatctaccg ttgaattaaa aggatatgaa
    16981 aaacctgtct tatatataga aaatatattt gatgatagct taattgaaaa cgtaaacaaa
    17041 gccttttatg aaaaggaaga aagaagaaag ataataagca acatgtttga tgaaaaagct
    17101 tttttcagta taaaggctaa tactaaagaa gaggtcataa tttcactttc aaataaacta
    17161 aaagaaagag attttataga ggaaagttct ataaaaagta taatagatag agaaaatatt
    17221 tcatcaactg aaataggaaa tctagtagca ataccccaca caatagtgaa gggagataaa
    17281 aaatctataa taggagttgg aatacttgaa aatccaataa tttgggataa gcaagaggtt
    17341 cagctagtat ttatggtatt ttttaatact aaagaaaaac ataatttctc gatatttaaa
    17401 tacctttata attttataaa agatgaaggc ggagtaagag gaattattaa aatatgtgac
    17461 tttaataaat taatggcact gataggtaat taaggaggaa attaataatg ggaacaaaca
    17521 tatttaacaa agaatatgta tttttaaatg ttgatgctaa gtcaaaggtt gaagttttaa
    17581 aatttatatc aaaaaaagct aaagacttaa acttggcaga agatgagagc ttagtatatg
    17641 aaggtttaat ggctagagaa gaacaattta ctacaaattt aggagaatct atagcaatac
    17701 ctcacactaa aaatgatgca attgaaaatc cagcagtagt agtattgaag tttaatgaag
    17761 atgttgtttg gaatgaaggt gaggataagg ttaaattagc aataagctta cttatgccag
    17821 gaaaaagtaa agagaatatt catcttaaat tattatcatc tctttcaaga aaattaataa
    17881 ataaagaatt taaagattct cttttaaaaa gtgataatgt tgaagaaata tctaacttaa
    17941 taaatgaagc tttaggttta taattaaaca ctaaggttat aaaataaaaa aataattaac
    18001 taaaaatagg aggaatttga aatgaataaa aaattagtag cattatgtgc ttgtccaatg
    18061 ggactagctc acactttcat ggcagcagaa gcaatagagc aagcagcaaa ggcattaggt
    18121 tatgaagcaa aagttgaaac tcaaggtgct gatggtgtac aaaatgagtt aacaagagat
    18181 gatatattag gagcaactat gataatacat gcagtagcaa taacaccaga aggtatggaa
    18241 agatttgatg gttgtgaagt ttatgaagtt gaattacaag aagctataaa aaatgcagaa
    18301 ggtgttataa aagaaataga agaagattta ggaatataat aaatttattg tggaggaaat
    18361 agaatggcaa ttaagaaaaa agttataaac agttcaggtg cttctacaac aggaggaaat
    18421 aatgtaggaa aatctactcc atctagtcca actcaatcaa agggaaatgg aaaatggaaa
    18481 gaaataagta aacatataat gacaggtata tcatatatga taccagtttt agtaatgggt
    18541 ggacttatag gggccttatc tcaattaata ccatatgcta tattaggact tgacccatct
    18601 gtaggtatag ttgatgctat gaactcagga gaatttacag ggttcaagct tagtctttta
    18661 aatatagcac aattaatgtc aaatttcgga tttactttgt ttggatttgc gataccactg
    18721 tttgcagcat tttgtgcaaa ctctataggt ggaaaaacag ctttaattgc aggatttata
    18781 ggtggatata tagctaataa acctgtaggt gtaccacaat tcgttgatgg acaatggact
    18841 gaagttgttc cagttgcatc aggattttta ggtgcaatac taatagcatt tataatagga
    18901 tattttgtaa aatggttaaa taaatctata aaagtttctc ataactggtt agcttttaaa
    18961 acaacatttt taataccatt aatagcgtca ttagcttgta tggtattgat gatatttata
    19021 ataactccat ttggtggatt aattaatgaa agtatgaaaa acttcttaac agcagcagga
    19081 gcagctggag aatatgtata tgcaacagct ttggcagcag ctacagcatt cgacttagga
    19141 ggaccaataa ataaagcagc aggattcgtt gcacttggtt taactacaga gaatgtactt
    19201 ccaataacag caagaacaat agctatagtt gttcctccaa ttggattagg gttaacaaca
    19261 ttattagata aaagattagt aggaagaaga gtatatgata gacaattcta tcaagcagga
    19321 aaaacttcta tattcttatc atttatgggt atatctgaag gagcaatacc atttgcactt
    19381 gagagaccag gttttgttat acctttaaac atagttggaa gtgtaatagg agctattaca
    19441 ggtataattc taggagcaat tcaatggttc ccagagtcag ctatatgggc atggcctcta
    19501 gtagataact tatttggata tataataggt atagcagttg gtgctatatt catagcagta
    19561 ggaaatatat tctatagaaa taaattaata aaagatggta aacttgttgt agattatatc
    19621 gactagtatt taatttttac tatctataaa taactttggc tggtaatatg gttttaatca
    19681 atattaccag ccttacctat atgattaatt aaaggcggtg gagataagat atggataaga
    19741 tagaaaaagt aagagagtat tttagagaat atgatataga tggatttctt ataaatagtc
    19801 ctacaaacaa gttttatgtt ggaaatttat ttagctcttc aggttatgtt tttataacga
    19861 aagaatcaca atatataata gtagatttta gatattttga agaaattaaa agaaaatcta
    19921 gtttgtttaa tgtagtatta atggacaaaa ctagaactca ttttgatata attaatgata
    19981 tttgtagaga gcagaatata aaggaaattg gatttgaggg aaatgaagta tcttttgatt
    20041 tatatagaag tatgagtaat aagttaagtg caaccttaaa atcagttgat ttatctacat
    20101 taagggaaac aaaaaatgaa gacgaaataa aatatataaa aaaagcttgt gaaatagttg
    20161 atgctacatt ttatcatata gtagacttta taaaggttgg tatgactgaa aagcaagttg
    20221 aaaatgaaat tgttagaatt ataaaagatt taggtggtca aaaagaatct ttcgatacaa
    20281 tagttgcatc tgggcttaga ggagcattac ctcatggaaa agcaagtgaa aaagttatag
    20341 agtatggaga ttttgttacc tttgactttg gtgctaagta taataattat tgttcagata
    20401 ttaccagaac catttgtatg ggtactataa ataaagagtt agaagaaata tataatatag
    20461 taagaaaagc taatgaagag tgtataaggg ttttaagacc gggaatgact actggagaga
    20521 tagataaagt tgcaagagac ataattggtt catatggata tgctggtaat tttggtcata
    20581 atctgggtca tggtgtagga attatggttc atgaatatcc tgcattagct cctgaatcaa
    20641 atgaagtatt aaaagaagga atgattgtaa ctatagagcc tggtatatat gttccaagtc
    20701 ttggaggcgt aagaatagaa gatgatgtac ttataacaca agatggatgt atgagattga
    20761 ctacatctac taaggattta atagttgtaa gctaaaaata aattagataa atattttata
    20821 acaataagaa aagaagaggt aaatttaaat gtataatttt gatgataaac cagatagagt
    20881 aagtgaaaag tgtagaaaat gggatttaaa tattataaga gataaatttg gagatattag
    20941 agaagatttt ataccaatgt ggattgctga tatggatttt aaaataccaa cagaaataga
    21001 aaacaaattt attgaagctg taagaagagg tgtatttgga tatacatact gttatgatga
    21061 attttatgat tcagttattg gttggcaaaa aaatatgcat gaggtaaatg tagaaaaaga
    21121 atggattaca ttaacttatg gaactgtatc aacacttcat tatgtagtac aagctttttg
    21181 taagaaaggt gatagtataa tattaaatac accagtttat gacccctttg aatcatcagc
    21241 aaaaaaacaa ggtgtaaatg taatttgtaa tacattagat gttgtaaatg atagatatta
    21301 tataaatttt gataaattag aagttcaaat taaagaaaat aagcctaaat taatgatgtt
    21361 ttgtacacca cataatccat ctggaaggat atggacaatt gaagaaatga caagggtagc
    21421 aactatatgt aaagaaaata atgttatttt ggttgcagat gaagtacatg cagagcatat
    21481 tcattatggt acatttaatt caatacttaa gattggaaaa gagcttttag aaaatgttat
    21541 tctattgaca tcaccaaata aaggatttaa tcttggtgga ttaaagactt cttattcaat
    21601 agttataaat aaggatataa gggacaaatt tagaaataaa ttaaagcaaa attctataac
    21661 ttctccaaat gtgtttggaa taataggatt gataaccgct tataatgaat gtcatgagtg
    21721 gttaagtggt gtaaatgaat atataaaatc aaattatgaa cttttagaaa cttgggtaaa
    21781 taaatataat aagataaaat tgatgaaaat ggaatcatct tacttagctt ggatggatat
    21841 aagtggatta ggtattagtg caagtgagtt tacagataaa ttggctatag atacaggagt
    21901 attattagaa gatgggagtc attttgtaaa agatggtgag aagtatgtta gaataaattt
    21961 aggaactcaa aaggaaaatg taattgaagc tttaaataga atggatttat ttttaaagtc
    22021 tttataaaaa tttggttgaa ttagtatttt atataaattt aaactattaa tatggtatat
    22081 acataagtag aatttgtttt agattactta agtatatacc atattttata taaaaattaa
    22141 atttgcatta gtcatgtgat aactatttaa attcatatgt attttgtatg tataatagat
    22201 ataattatta tttaaactta ttgtttattt aatttttcaa tagaaaaaga tttatctgta
    22261 agtttaaaat tatcttttat acccttagtt aagtatactt tcttatcctt agttatgaat
    22321 atagcatcta cattatcaat tttattaatt aaattcatac ctttttcaag accaagacca
    22381 aatgtagaag tggataaggc atcacaatta atagatttat cagagattat tgtaacacta
    22441 cttaaattgt tttcaaaagg ataccctgta aatggattta acatatgatg atatattttt
    22501 ccgttttttt cgataaatct ttcataaatt ccagaagtaa caacagactt atttgtagtt
    22561 tctatgtttc ctatggattc accattttta ctagttgggt cttgaatacc tattttaaaa
    22621 ggtttatcat ttttaccatt ttctaaagta aatatatttc ctcctaagtt tactaaacct
    22681 ttttttacgt cctctgattt taaataggct acaattttat cagcagcata tcctttagct
    22741 atggcaccta aatcaatttt catattttct ttggttaatt ttatagattt atttttttca
    22801 tccaatatga tgttcttata atcaataaga ggcagaagtt tttgtatctc agaatcactt
    22861 ggaactttag ctttatctgt tccaatagcc cataaatttg ataatggacc aattgttatg
    22921 tcaaaatatc catctgataa tttggaatat tgtatagctt cttttacgac gaaaaatgta
    22981 tcatcagaaa ctctgacaaa ttttttacca gcattatcat ttattttaga aacatcactt
    23041 cctggtatat gagtgctcat tttgttgtca atatatctta aaattgaatc acattcattt
    23101 aagattttat cacttttgga ttcttttaca ttaaatacag taacttcgtt tactgtacca
    23161 aggtagtagc tagttttact atatttagta ttctggcttg aactcctaaa aaatgaaaat
    23221 aaaattaatg ctaaaatcaa tatcacaaaa ataaatgtga tttttttctt attcatggta
    23281 tattcctcct atgaaattgt gttattattt tattataaca taatttcata ggaggacaaa
    23341 aaatgaagaa aaaagacatt cttcttattt taggcatttt ggttgttatt acagcatgtt
    23401 atgggataat aaatgttata aattctaaaa atgctggaaa tattgagatt tatgtagata
    23461 ataaattgta taaaactgtt tcaataaatg ccaaagaaga atttaaaata gagaatagag
    23521 gggggtataa catagtaaag attcatgata aaggggttga gatagtagat gcttcatgtc
    23581 ctgataaggt ttgcgtacat actggattta taaacaagcc aagtcaaagc atagtttgta
    23641 tacctaatag agtgagcata aaaataaata caaatgaaaa gaatgataat caagaagata
    23701 taatttctaa ataaaataat aaaaataatt gaaaggaatt ggtgataatt atggttaact
    23761 taggaaacga ttgggatgaa ttattgaaag aagaatttga aaaagattac tacttaaact
    23821 taagaaaatt tcttatagaa gaatataaaa cacgccaaat tttcccaaat atgcacaata
    23881 tatatgaagc tttaaaacac acttcataca aagacacaaa agtcttaata ttaggacaag
    23941 acccttatca tggagataat caagctcatg gtttagcttt ttcagttcaa ccacaagtga
    24001 aaactccacc atctttatta aatatgtata aagaattaaa agatgattta ggttgtttta
    24061 tacctaataa tggatattta atgccttggg cagaccaagg agtgttactt ttaaatactg
    24121 ctcttactgt tagagcgcat gaagctaatt ctcataagaa caaaggatgg gaaattttca
    24181 ctgatagagt aatatctatt ttaagtgagc gtgaagaccc agttattttt gtactatggg
    24241 gaagtaatgc acgtaaaaaa gtagagttga ttgatacaag taaacattat attttggaag
    24301 cacctcatcc aagcccattg tcagcaagta aaggcttttt tggatgtaaa cacttctcta
    24361 agataaatga aattttgaaa aagctaggaa aagaacctat taattggcag atagaaaata
    24421 tataaaagta aaaggtaaca aaatgataac aaaacaacaa taaacaatga cattgttgta
    24481 actaatagaa atatgcttaa atagttgaaa atactatgta tgcatatttc tatttttttg
    24541 tcaagttgac aactcttgaa aaaatagtta caatttagtt acacaaaaaa cacaaataaa
    24601 aaaagaaact tacaaagcag aattttatga agcaaaatat atagtgtaaa aaatcttagg
    24661 gaggaaattt tatatgaatt ttaaaaaatt gagtaatgct aaagtctcgg taatggcagt
    24721 tgttttatca gttggaatat tatcgggata ctctgcgctt aataaacaag taacattagt
    24781 agtaagggga gaagaaagaa ctatatcaac atttagttct aatgtaggag accttttaga
    24841 atctcaaaac attagctatg atgcaaatga tatagtaact ttagatgaaa atacaaagtt
    24901 atctaatgga gataaaatag aagtaattga tgtaaaggaa aaaacagttg tagaaactaa
    24961 agacattcca tttgaagtta cagttgttga agatggctct ttattaaagg gtgattctaa
    25021 ggttaaagaa gaaggaaagt ctggtaaaag tgaattaata tataaagaaa cttatcacaa
    25081 tggaaagaaa gtagaaaagg aatttgtgaa aaaggttgtt aaagctgagc cagtaaataa
    25141 ggttgtaagc aaagggacaa aggtagaaat gcaagtagcc tcatcaaggg gagaaagttc
    25201 aagaagaatg gcttcatcat catctagtag cagtagtagt aacaatggta aaaatatgag
    25261 agtggtagca actgcatata ctggtcacag tataactgca acaggaacaa aacctaagtg
    25321 gggaacaata gctgtagacc ctaaggttat accatatgga actaaagttt atatacctca
    25381 atttgacatg gtgtttactg cagaagactg tggtggagca ataaaaggaa ataaaattga
    25441 tatctacatg aatgattcaa aaacagttta taactgggga agaaaaacta tagatatacg
    25501 tatattaaaa tagttaaata atttatattt ttactggaaa ttatattttg attatataga
    25561 gaagaaactc tttatagatt ctaaaaatat aatttccagt tttttatttt ggatatgtaa
    25621 taaaacaggt aaattttaac catgtataga taaaagctat ttaaattata atttactatc
    25681 atataaatct ataaaaattg ttgcaaagag tcaaaatata tgatattata gatttcgttg
    25741 agaaggattt cattatggga gtggatgggt gccggtgtgc cctctagtct tcaaaactag
    25801 tatgaggggt taagagcctc ttaggtgggt tcgattccca cgcattcccg ccaatatgta
    25861 aaaggtatct tttaattaaa agataccttt ttaaatttgt tttaagataa tttagtttta
    25921 atgatatata atattttgta ttatataatg taaattttat aatactatta ttgttcagat
    25981 aaaagtctag gagagtgaaa agatggaaaa taattttaca acgagaacta gttttctagt
    26041 tggagatgat gggatagaaa aacttaataa ttcaaatata atagtatttg gagttggagg
    26101 agttggtagt tttactgttg aagctttagc aagagctgga gtaggcaata ttactattgt
    26161 agattttgat gatgtagata taaccaatat aaatagacaa ataccagccc tacattcaac
    26221 tgtaggaaga tacaaagttg atgtcatgga agaaagaata ttagatataa atcctaatat
    26281 caatataaaa aaaataagaa gtctttataa taaagatact agtgacgaaa tactaactga
    26341 aagatatgat tatgttgtgg atgcgataga catggtaagt tccaaaatac atctaattga
    26401 aacttgtgaa aaaaaaggat tgaaaataat aagttctatg ggtatgggaa ataaattaga
    26461 cccaactaaa atagtcgtta cagatataca caaaacaagt acttgtcctc tagctaaagt
    26521 tatgaggaaa gaacttaggg atagaggtat caaaaagtta aaagtagtat attctactga
    26581 acaaccaata gaacttaaga agaaagtaat gaatggtaga aaagtaacac ctggtagtgt
    26641 atcatttgtc ccatctgtag gaggtttaat aatcgcatct gtaatagtaa atgaactatt
    26701 aggacaataa gttttaaata ttttaattta taaattttat atacaaattt gaaggctaga
    26761 aggatgaata taaagcaatt ttatattcat acttttagcc tagttatttt atattacctt
    26821 attttatgta gttgtagctt tattttttag attatgtatc tatttcataa ttatattttg
    26881 taaatataat ttctccatca ctataaaaaa caatatctcc tattctgtct gttctataaa
    26941 ttgatacatg gttttgtttt agattattaa taacctccct atgtggatga ccatattgat
    27001 ttttatatcc acatgatatt gcagctatat ctggactaat tttttttata aattctaaag
    27061 atgaagaaga attacttcca tgatgaccta tttttataaa attaatatta tttaatttaa
    27121 aagaatgtaa aatttctttt tcattttctt cttcagcatc acccataaat aaaaaagaat
    27181 tatcattaaa agttaatttg aaaactatag aatttaaatt agattcttct tgtatatatg
    27241 atggacttaa tacatatata tttatattgt tatctatgtt taaaacatca tttttataga
    27301 gatgctgaat agataagttt ttatccgtac aagaatttat tagattttga taagcctcac
    27361 tatcagttga ttgttcaggc atatatatgg agtttacatt aaattttttt ataatattat
    27421 caagacttcc tatgtggtct gaatctggat gagttgctat tataatatca atagttttta
    27481 ttcttttttg tctaagataa ctaataatta tattttcgct atcttcatca cctccatcaa
    27541 ttaatatatt cttatttgtg ggtgtttgaa ctaaaatact atcaccttgt ccaacatcaa
    27601 tcatatgtat agatagtaga gattttttgt cacagccgat taaaagtgat at
//
LOCUS       DAYAKB010000046        27530 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.046, whole genome shotgun sequence.
ACCESSION   DAYAKB010000046 DAYAKB010000000
VERSION     DAYAKB010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.046"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            206..1900
                     /locus_tag="ACGI3L_002379"
     CDS             206..1900
                     /locus_tag="ACGI3L_002379"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFG9198079.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYIRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      2232..2342
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            2446..2817
                     /locus_tag="ACGI3L_002380"
     CDS             2446..2817
                     /locus_tag="ACGI3L_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HFG9198080.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            2912..3859
                     /gene="trxB"
                     /locus_tag="ACGI3L_002381"
     CDS             2912..3859
                     /gene="trxB"
                     /locus_tag="ACGI3L_002381"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFG9198081.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            3963..4280
                     /locus_tag="ACGI3L_002382"
     CDS             3963..4280
                     /locus_tag="ACGI3L_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HFG9198082.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            4549..5835
                     /locus_tag="ACGI3L_002383"
     CDS             4549..5835
                     /locus_tag="ACGI3L_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HFG9198083.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            5947..6420
                     /gene="grdA"
                     /locus_tag="ACGI3L_002384"
     CDS             5947..6420
                     /gene="grdA"
                     /locus_tag="ACGI3L_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_110943085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:6079..6081,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HFG9198084.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            6452..7762
                     /gene="grdB"
                     /locus_tag="ACGI3L_002385"
     CDS             6452..7762
                     /gene="grdB"
                     /locus_tag="ACGI3L_002385"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:7499..7501,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HFG9198085.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            8018..9550
                     /gene="grdC"
                     /locus_tag="ACGI3L_002386"
     CDS             8018..9550
                     /gene="grdC"
                     /locus_tag="ACGI3L_002386"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit beta"
                     /protein_id="HFG9198086.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            9561..10706
                     /gene="grdD"
                     /locus_tag="ACGI3L_002387"
     CDS             9561..10706
                     /gene="grdD"
                     /locus_tag="ACGI3L_002387"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit alpha"
                     /protein_id="HFG9198087.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            11016..12095
                     /locus_tag="ACGI3L_002388"
     CDS             11016..12095
                     /locus_tag="ACGI3L_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFG9198088.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            12208..12807
                     /locus_tag="ACGI3L_002389"
     CDS             12208..12807
                     /locus_tag="ACGI3L_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198089.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(12993..13865)
                     /locus_tag="ACGI3L_002390"
     CDS             complement(12993..13865)
                     /locus_tag="ACGI3L_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9198090.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            14282..15685
                     /locus_tag="ACGI3L_002391"
     CDS             14282..15685
                     /locus_tag="ACGI3L_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198091.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            15712..17256
                     /locus_tag="ACGI3L_002392"
     CDS             15712..17256
                     /locus_tag="ACGI3L_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HFG9198092.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            17287..18678
                     /locus_tag="ACGI3L_002393"
     CDS             17287..18678
                     /locus_tag="ACGI3L_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HFG9198093.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            18871..20367
                     /gene="abfD"
                     /locus_tag="ACGI3L_002394"
     CDS             18871..20367
                     /gene="abfD"
                     /locus_tag="ACGI3L_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HFG9198094.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            20502..20777
                     /locus_tag="ACGI3L_002395"
     CDS             20502..20777
                     /locus_tag="ACGI3L_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198095.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            20801..22108
                     /locus_tag="ACGI3L_002396"
     CDS             20801..22108
                     /locus_tag="ACGI3L_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase C-terminal
                     domain-containing protein"
                     /protein_id="HFG9198096.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVREHLAVEFEKRFKEKY"
     gene            22128..23246
                     /locus_tag="ACGI3L_002397"
     CDS             22128..23246
                     /locus_tag="ACGI3L_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HFG9198097.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            23533..24453
                     /locus_tag="ACGI3L_002398"
     CDS             23533..24453
                     /locus_tag="ACGI3L_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFG9198098.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            24568..25725
                     /locus_tag="ACGI3L_002399"
     CDS             24568..25725
                     /locus_tag="ACGI3L_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFG9198099.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(25810..27309)
                     /locus_tag="ACGI3L_002400"
     CDS             complement(25810..27309)
                     /locus_tag="ACGI3L_002400"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFG9198100.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
BASE COUNT        10746 a         3130 c         5172 g         8482 t
ORIGIN      
        1 ataaatagac tgatggtaat ttgttatatt agttagtttt gtgttataaa atattgtaat
       61 tccattaatc atatgttatt attcaacatg attataatat aaagaatatt tgatatatat
      121 aataatttat aaaagagtat tacatagtac atataaatct atatttataa atacaataaa
      181 gtaaagttgt aaaggagtgc tttaaatgaa gttttcagag tttaagtatg aaagacccaa
      241 ttataatagt atgaaaaaag agtttttgag ttgtgtagaa gatataaata attctcgtaa
      301 ttataaagag caacaaaaaa atatacataa gattaattta ttaagaaata aaatagaaac
      361 gttgtcaaat atagcttcga taagatatag tacagacaca tttaataaat tctacaaaga
      421 agaaaaaaat tattgggatg aatatatgcc tttgtatgaa gaattaaatt catattttta
      481 taatgccatt gtaaattcaa aatttaaata tgatttgata aaagagtttg gagagcaatt
      541 tttcacaata gtagagtatt ctttaaaaag tttttccaaa gaaataataa gtgaattgca
      601 ggaagaaaat aaattgtgtt cagagtatac tagactttta gcttcagctg agataatgtt
      661 tgatgggaaa ataagaaatt tatctggtat ggggaaattc atgtattcta agaatagaaa
      721 aacaagagaa ttagcaaaca aagcatatta taatttcttt gaagaaaatg aaactaaatt
      781 tgatgatata tttgataaat tggttaaact tagagataag atgtctaaaa aattaggttt
      841 tgaagatttt gtagagcttg ggtacattag aatgatgaga agtgactaca gagaatatat
      901 gataaaaaat gttagaaaac aagtactaaa atatgttgtt ccaatggcaa atgagcttta
      961 tgaaaaacaa gctaaaagaa ttggtctaga atatttaagt tacatagatg aaggcgtgga
     1021 atttttaaca ggaaatgcaa gtttaaaggg agattcaaga tacataatta aaaatggtaa
     1081 aaggatgtat tctgaactgt caaaagaaac aaatgaattt tttgatttta tgttagaaaa
     1141 tgaacttatg gatttagaaa cgaagaaagg aaaaggagct ggagggtatt gtacttatat
     1201 accagattat aagtcaccat tcattttttc taattttaat caaactgctg atgatataga
     1261 tgtattaaca catgaggcag gacatgcatt tcagttgtat atgtctagat ggattgatat
     1321 gccagaaatt aattttccaa cgcttgatag ttgtgaaatc cattcaatga gtatggaatt
     1381 tataacatgg ccgtggatgg atttattttt taaagaagat acagataagt acaaattcac
     1441 tcacttatca tcttcaatta aatttatacc ttatggagta attgttgatg aatttcaaca
     1501 ctatatttac aaaaatccta atgtagataa gtcaaaacga aaagaaatct ggagattttt
     1561 agagaaaaaa tacttacctc atagaaaata tggtgataat tcttttttag agagaggttg
     1621 ttggtggttt aaacaaggac atatatttaa aaatccgttt tattatatag attatgtatt
     1681 agctcaaatt tgtgcgttac aattttggaa aaaaatgatt caagatagag atgcaggatg
     1741 gaaagattat ataaatatct gtaaagttgg aggaacaaaa tcatttttag atattgtgag
     1801 tatgggaaat ttgtattctc catttgatga tggctgtatt gagtctatta taggtgatgt
     1861 taaatcttgg tttgatgaaa taaatgacag caaattataa aaaattatga gaattttatt
     1921 gtataaaagt aaaaaattaa aaaatatata aaaagtgatt atttgttgtg aaaatagtct
     1981 tgtttttaac taaattgata aaataaacta aaaaagattt gtacttaaaa aaaaaagaaa
     2041 atacaagaaa tatgcaatat caacatttgg aaaaaaaagt aaaaatgtat acaaaataca
     2101 tataaaaaaa ctattgcaaa ttttatagaa tgtttatata cttaagtcaa cagagataga
     2161 aaaaagctat ttatagaaaa caaaggataa attgcttaat tttaaatttt ctgaaaaaaa
     2221 taataatccg gatgaagagt atgggagact gctttataaa aagcgaccga agggacaagt
     2281 ttaatcttac ttacccaaaa gattagatga aattctcagg taaaggtgac tgtacttgga
     2341 cggggctctg aaaatgattt taacagggaa gacaaattgg gagatttgtt tttcctgttt
     2401 tttatttatc aagtaataaa taaaagtttg aaagagagta aaaaaatgat aataattacg
     2461 aataatccaa aagtaaaaga agaagttcaa ggcagagaag ttttgtttaa agacacaact
     2521 tatattggaa tcttagaagc aagtagagat ttgatacatg aaggttatga acttttatct
     2581 catccactct atgggagtgt aaagccaaat gaaacacctt acaggactgt tatactaaag
     2641 aaaggaaatc gtttggatat aaactcttta accttaattg aagaagcaat catcactgca
     2701 agtaaatttc agaataataa aaagactcca aaatggacag aaagtgttca agatgatttt
     2761 agagtaattg attatgatat attttataat acaatacaaa gaatgcagta tgaataaaaa
     2821 aattgttaaa aagttattaa aacagcctaa atattaaatc taatttaata ttaaataaaa
     2881 tgagaaattt aattggggag gataagtcaa aatggaaaat gtgtatgact tagtaataat
     2941 tggttcagga ccagcagggc ttgcagcagg tctttatgga gcaagagcaa agttaaaaac
     3001 tctaatccta gaaaaagaca agactggtgg acaaattgta ataacacatg aaattgcaaa
     3061 ttatccaggg tcagttccaa atgcaacagg accaagttta atagctagaa tggttgaaca
     3121 gtgtaaagag tttggagcag aaatgctaag agacaacatt gttgatactg agctagatgg
     3181 agatataaaa gttttaaaag gggaaaaggc agaatataga gcaaaagcag taataatagg
     3241 aacaggagca acaccaagaa agattggttg tcctggagaa aaagaactta ctggtaaagg
     3301 ggtttcatat tgtgcaactt gtgatgcaga tttctttgaa gattttgaag tatttgttgt
     3361 aggtggagga gacagtgcat tagaagaagc aatgtattta actaaatttg ctagaaaagt
     3421 aacaattgta catagaagac aaggatttag atgtgctaag agtgttgaag aaaaagcaaa
     3481 agctaatcca aagatagagt ttttattaga tacagtaatt gaagaaatca aaggtgatgg
     3541 aatattagaa tcagttgtat ttaaaaataa agttactgga gaaactcatg aatactttgc
     3601 agatgaagaa gatggaacaa tgggagtatt tgtgttcgtt ggattagatg ctcaaactga
     3661 tttattcaaa ggtaaagttg atatggatga aaaaggttac ataataactg atgaagatat
     3721 gagaactaac ataccaggcg tatttgcagc aggagattgt agatctaaga ctctaagaca
     3781 ggttgtaact gcaactaatg atggagcaat tgcatctata gtagctgaga aatacattga
     3841 tgaaaaattt gggaactaga atctgtaaat taagaaatag tgtctgtaaa tttaatgaat
     3901 aatatttaaa attaaaatta atatttaaaa taaaaataaa aatttcaagg gggaataaga
     3961 aaatgttaga tttagataag gctacatttg aagaagaagt tttaaatgca gaaggttttg
     4021 tatttgttga tttttggagt gaaggttgtg agccttgtaa agctttaatg ccagatgttc
     4081 ataaattagc tgagacttat ggggataaaa taaaattctg taagatggat acaacaaaag
     4141 ctagaagatt agctataaaa caaaaagtat taggtcttcc aactatggct atatacaaag
     4201 atggagaaaa agtagacgaa gttactaagg atgatgctac agttcctaat atagaaaaca
     4261 tgattaaaaa atatctttaa tatgttgata aattattaac attaaaagaa aaaatctatt
     4321 tttatctgaa gataagaaga aaaaggtttt tatgtccaac tttgttaaaa aaataatttt
     4381 aaataaaata atttttttac aataaatatt ttttagtaat aaaataaaga tttaaggcat
     4441 aaaaacacaa taatatatct ttaaaaaaat aagataaatt gtaaaatgat ataattttga
     4501 gaaaaactca aatgcatata cacaaattaa ataacaggag gtgcaagtat gcgtcttgaa
     4561 ttagggaaaa tctttataaa agatattcaa tttggtgatg taacagaagt aaaagatgga
     4621 gtattattca tcaataagca agagatgcta caagaaattg gtggagatga gcatattaaa
     4681 tctatagata tagaattagc tcgtccaggt gaaagcgtaa gaataacacc tgtaaaagat
     4741 gttattgagc caagagtaaa agttgaaggt aatgggggaa tcttccctgg tatcatgtct
     4801 aaagttgaca ctgtaggaga aggaaaaact catgctttaa aaggtgtagc tgttgtaact
     4861 actggaaaaa tagtaggttt ccaagaaggt ataatagaca tgactggaga aggagctaag
     4921 tacactccat tttctaaatt aaataatgta gtagtaatag ctgaacctat tgatggttta
     4981 aaacaatacg ctcatgaaaa agctgttaga atgataggat tcaaagcagc aatgtactta
     5041 ggagaagtag caagaaatct tactccagat gaagtttcag tatatgaaac taaacctctt
     5101 cttgaatcaa taaaagaata tccagagctt ccaaaagtag gatatgttta catgcttcag
     5161 actcaaggtt tattacatga tacttatgta tatggagtag atgcaaaaca aatagtacca
     5221 actttattat atccaacaga attaatggac ggagcaattg taagtggtaa ctgtgtttct
     5281 gcatgtgaca aaaacccaag ttatgttcat ataaacaatg gggttgttga agacttatat
     5341 gcaagacatg gtaaagatat aaactttgta ggtgtaatta taactaatga aaatgtttat
     5401 ctagcagata aagaaagatc ttcaaactgg acttctaaat tatgtaaata tttaggatta
     5461 gatgcagtta tagtttcaca agaaggtttt ggaaatcctg atactgacct tataatgaac
     5521 tgtaagaaga tagaaatgca aggtgttaaa acagttatag ttacagatga atatgctgga
     5581 cgtgatggag gttctcaatc acttgcagat gcagatgtaa gagctgatgc tgttgtaaca
     5641 ggtggaaatg ccaaccaagt tgtagttctt cctaagttag ataaagttat tggacattta
     5701 gaagtagtag atgtaatagc tggtggttct gatggaagtt taagagctga tggaactatt
     5761 gaagttgaaa tccaagctat aacaggtgca actaatgaaa caggatttgg tcatttaact
     5821 gctaaaggat attaagaagt attttattaa acgattgagt aatgttaata aaacatatta
     5881 tagataatta taataagtgt tatagatata taaaaatata ttagaaatat aataaggagg
     5941 attattatga gtttacttag taataaaaag gttcttataa taggtgaccg tgatggtata
     6001 ccaggacctg cgatagaaga atgtgtaaaa acagtagaag gagcagaggt tgttttctca
     6061 tctacagaat gctttgtctg aacagctgct ggggctatgg acttagaaaa tcaaaacaga
     6121 gttaaagatg ctgctgataa attcggagct gaaaatgttg tgattttact aggtgctgct
     6181 gaagccgaag ctgcaggtct tgcagccgaa acagtaactg ctggagatcc aactttcgct
     6241 ggaccacttg ctggagttgc cttaggatta agtgtttacc acgttgttga ggaaccaata
     6301 aaatcattat ttgatgaaag tgtatatgag gaccaaataa gtatgatgga aatggtttta
     6361 gaagttgaag aaatagaaga agaaatgtct ggtataagag aagaattttg taaattttaa
     6421 tgcctaaaag caaaaggggt gaaactaaga gatgggaaaa ctaaaagcag tacattatat
     6481 taatcagttc tttgctggta taggtggaga agaaaaagct gatactaagc cacatgtggc
     6541 agaaacttta cctccaataa gtttacaact tgataaatta ttaggtgaag atattgaaat
     6601 agttggaaca gtagtttgtg gagatagcta tttcaatgaa aatatagata gtgcaagtga
     6661 agaagtttta tcaatggtaa aaggttttga accacaactt ttcatagctg gtcctgcatt
     6721 taatgctggt agatatgggg ttgctgctgg aacaataact aaagttgtaa aagatgcttt
     6781 gaatatacca gctttaacag gtatgtatgt tgaaaatcca ggagcagata tgttcaaaaa
     6841 ggatgtttat gtagtagaaa cttctgattc tgcagcaggt atgagaaagg cacttcctaa
     6901 gatagctaaa cttgcagtaa aacttgctaa tggagaagaa attggaactc ctaaagatga
     6961 aggatacata gctagaggaa taagagttaa ctacttccat gaagacagag gttctaagag
     7021 agctgttgac atgttagtta agaaaataaa aggtgaacca tttgaaactg aatacccaat
     7081 gccaaacttt gatagagttg acccaagtaa agctgtaaaa gatttatcaa aatgtaaaat
     7141 agctttagtt acttctggtg gtatagttcc aaaaggaaat ccagatagaa tagagtcttc
     7201 ttcagcttct aaatatggaa cttattctat agcaggagtt atggatttaa cagaagagac
     7261 ttatgaaact gcacatggtg gatatgaccc agtgtatgca aatttagatg cagatagagt
     7321 attacctgtt gatgttctta gagatttaga aaaagaaggt gtaattggaa aattacatga
     7381 gactttctat acaactgtag gtaatggtac atctgttgca aactctaaaa aatatgcttc
     7441 tgaaattgga gcagcattag tggctgatgg tgtagatgca gtaatattaa cttctacatg
     7501 aggtacttgt actcgttgcg gtgcaacgat ggtaaaagaa atagaaaaaa ctggacttcc
     7561 agtagttcat atgtgtacag tagtacctat ttcattaaca gtaggggcta atagaatagt
     7621 tccaactata gcaatacctc atccacttgg aaatccagcg cttgacccta cagaagaaaa
     7681 agccctaaga agaggccttg tagaaaaagc attaaatgct ttaactacag aagtagatgg
     7741 tcaaacagta tttgaaaaat aaaaataaca cacacatata ttatatagat aaaaatataa
     7801 acacacacta aaaataaaaa ataactatac acaaaaaaat aatatagatt tcatgaatgg
     7861 ataaattgga gttattcatt catgaaatct taaaaaatgc caaaatacat aaacaataat
     7921 agaatcaaat atacaataaa atacaatgat tagagctttt aataagttta ataagattaa
     7981 aaaataagtg ttcataaaat ttatggaggt gcacaaaatg acttatccag ttttaaaagg
     8041 ggcaggctat gtacttattc atactccaga tatgatagtg caaaatggaa gtacttgtac
     8101 agttgaaaga gcaacaaatc cagattcaga atttttaaaa gaagtaagta atcatataag
     8161 aagttatgaa gatgtagtta actacatgcc aaatcaagtt tatataggaa atagaagacc
     8221 agaagaatta agagatttac caatgccatg gtgtgaacaa aagattgagg gaactagaaa
     8281 tggtaagttt ggagaaataa tgcctcaaga tgagttcata gctttaatgc aaataagtga
     8341 tgcatttgat ttagtaaaat tatcacaaga atttattgat gaagtaaagc caaaaatcga
     8401 aaataactac cctgaaattg caccatttgt aggtaaatta aagggtgatg atatagaaga
     8461 aggtaaagaa ttagtagcaa cacacatagc tgaaggatta taccatgatg gaaaatttgt
     8521 tggttatgta aaaagagcac atgatgtaga tgttaactta aatgcccata caatgtttga
     8581 aaatctagta gtaaaagcat ctggagtttt atctgctatt caaatgctaa gacatagcaa
     8641 aatagaccct gctgaaatag attatgttat tgagtgttca gaagaagctt gtggagatat
     8701 aaaccaaaga ggtggaggaa actttgctaa atcaatagct gagatagcag gacttcaaaa
     8761 tgcaactggt tctgacacaa gaggattttg tgcagcacca actcatgcat taattcaagc
     8821 agcagcttta gtaaaagctg gtatacataa aaatgtaatg gtagtagcag gtggagcaag
     8881 tgctaaactt ggaatgaatg ctaaagacca tgttaaaaaa ggtcttcctg tacttgaaga
     8941 tgttgttgga ggatttgcag tacttgtatc tgaaaatgat ggtgtaaatc cagttataag
     9001 aactgattta acaggtaagc atactgttgg aactggttct tcaccacaag cagttatgac
     9061 agcacttata acttcaggtc ttgatagagc taatttaaaa ataacagatg ttgatgtgta
     9121 ttcagttgaa atgcaaaacc cagatataac taagccagca ggagcaggag atgttccaga
     9181 agcaaactac aaaatgatag gggcacttgc tgttaaacgt ggagacttag aaaagaaaga
     9241 attgaaagat tttgtttcta acaaaggatt accaggatgg gcaccaactc aaggacatat
     9301 accatcagga gctccttata taggattttt aatagatgat ttaactacag gaaatagaaa
     9361 tagagctatg atagttggaa aaggtagttt attcttagga agaatgacta acttatttga
     9421 tggagtatct tttatagctg aaagaaatac aggtgttact gaagagactt caggaatatc
     9481 taaggatgaa attaagaaga taatagctga atctatgaaa aaactagcat tagatatgtt
     9541 agaagaatag gggtgaggat atgtcaaaaa aagtaatcgc agatgtattc ttagaagtag
     9601 ctaatgcaat agaaagcggc gaatttggca aaaaagtaaa aattggtgtt actacacttg
     9661 gaagtgaaca tggtgtagaa aacatggtta atggtgcaca attagcaaaa tctaatttat
     9721 ttgatattgt gcttattgga ccaaaagtgg aaactgacct tgaagtagtt gaagttaatg
     9781 atgaaaaaga aatgcatgca aaaatggaag aattattaga ttcaggatat attgatgctt
     9841 gtgttactat gcattataat tttccaatag gtgtatctac agtaggtaga gtaataactc
     9901 cagcaaaagg aaaagaaatg atacttgcaa caacaacagg aacaagtgct actaatagaa
     9961 tagaggcaat ggtaagaaat gccatttatg gtattgctac agctaaatca atgggtaaca
    10021 aatgcccaaa agttggaata cttaatgttg atggagcaag acaagttgag aagtgcttaa
    10081 aagaattaaa agataatgga tatgacatgg agtttgcgga ttcaattaga gcagatggtg
    10141 gatgtgtaat gagaggtaat gatttacttg taggtgcacc tgatgttatg gttactgata
    10201 cattatctgg aaatatattt atgaaagtat tttcttcata tactacaggt ggagattatg
    10261 aagctcaagg ctttggatac ggacctggag ttggagagga ctatgataga aaggtactta
    10321 tagtatcaag agcatcaggt tctccggtag tagcaaatgc tttaaaatac gcttatgatg
    10381 ttgtaaaggg agatataagt aatgttgcaa gaaatgaatt tgcaaaggtt aaaaaagcaa
    10441 aatttgatga cattatatcc tctcttacta aaaaagaagt taaagctgaa aaagtagaag
    10501 ttaaaatgcc agataaagaa attgttactc gtcaaatagc tggtgttgat ataatggatt
    10561 tagaagatgc agtatctgag ttatggaaaa acggaatcta tgctgaaagt ggtatgggtt
    10621 gtacaggtcc aatagtttta gtaaatgaag ctaaaggaga cttagcagtt gaaactttag
    10681 ttaaagctgg atatactgca aaataagtac attttttata tgtaaataag aacatatagt
    10741 tataatttta ttgattataa ttatatgttc tttttatttt atatcttgtc aatatttata
    10801 tattaacaca atccatttat ttgattctct agctaattta ttatatttat tcagttaaaa
    10861 ttaagctttc taactaaata aaaactaatg aagtattaaa atgaaattga taaaatatga
    10921 aaaaatttta ggaataaagt atctgttaga taaaaataag attaattagt gatataatat
    10981 aattaagata aaatttatta tttggaggca aaatcatgag cagagtaaaa aatgtagtag
    11041 aattgttgga aactaaaggt gttgatgcac tatatctaac aaagaaaact aatgtaaact
    11101 atataagtgg ttttcctgat gaagaagcat atgcagtgat ttgcaaagat ggaaactttt
    11161 tagttactga tagtagatat atggagcttg cagaaaaggt ttgcaaagat tttgaaatta
    11221 taaattggca taattttgat agaagtgtgg caaaggcagt taaaagtgta tgtgataaag
    11281 tgggtataaa gaaacttggg tttgaaagaa ctaatatagt gtttgataaa tatgaagaac
    11341 ttaaaaatct gattgagaag gataatggag aattaatacc tacagaaaat attgtagaga
    11401 ctttgagata tgtaaaagac aaagatgaaa tcaaaaatac aagaaaagct tgtgaaatag
    11461 cggataaggc attagaagaa ttgattccac atataaaagc tggagttagc gaaattgaac
    11521 tggctacaaa gttagagtac tttatgaaaa tgaacggagc acaaaatata gggtttgaaa
    11581 ctatactgat atcaggagca aagacttcat tgcttcatgg taagcctagt gataagatta
    11641 tagaaaaagg tgattttgta cttatagact atggcgctat gtataatggc tatatatctg
    11701 atacaactag aacttttata gttggaggag cttctgaaaa gcaattagaa atatataatt
    11761 tagttaagga agctcaaaat gtaggggttg agaacatgaa agctggtgta catgcgacaa
    11821 ttccagatgc tgagataaga aaagttgtca aaaaatatga agactattac tatcaaggta
    11881 taggacatgg agtcggtaga gatgttcatg aagaaccttt cattggtaat tatggtgata
    11941 aaatcataga agagggatgt ataataacaa tggaaccagg tatttatttc cctggatggg
    12001 gtggagttag aatagaagat actgttttga ttactaaaaa tggtccagaa agacttacta
    12061 aattccctaa agatttgatg attttagaca aataatttaa tttatatata tttttttaca
    12121 taaaatataa cataatctca ctattaagct ctatttacat attatagtaa agagggctta
    12181 attttattgt gagaggtgat agtatatatg tataaaaaac ataaatttat aaaaaatata
    12241 aaaaaagcct ggtataaaat caaattaatt gatagatgcc ttataattgt aatggcaata
    12301 ttaatgtttc aatctatata taatttattt gttaatgaag taaattcaca agatactaca
    12361 actattgatg tagtagtaag aaccacttca gcagctatat ttgggtattt tttaagtgct
    12421 aattttataa agagaccttt aaggaagtat acaaatactg atgtatcttc aaatcttttt
    12481 atagataata atttatcccc aaaaggtcaa gagtctaatc aaaataatat aatgaatgtc
    12541 aaaaatacca ttggatttac ttcagaagct gataattatg aaaagaaaat acctattaat
    12601 aataatgaag gttttgaaga aggagaaact agtgaattgc aaattattat agctactgta
    12661 atttgtatag tagcattaac agtacttttt gttgtaagaa attttacaac tacaacatca
    12721 gcttctttag gtactatttc acagatgaga gattttgtct caggatgcgt gggttttttg
    12781 ctaggttgtc caagtaaacc tgattaaaaa agtattatca ataaaaggta ttttaaaaag
    12841 tatcagtata ataatattta gatttaaatg tatacaatta taattctaaa cattctatat
    12901 tgtattttta tactgatact ctaaactata ctatttatta aaatatttta acattgtatt
    12961 taaacaaaat attatatctg tataatataa atttagttta tatgaataga tgccatatac
    13021 tcaataaaaa gtttcatact atgagatatg tattgatttc ttctccaaag aaccccaata
    13081 ttcgcagtaa ttgcacgttc taatggtatt gaacagagat tttctgtatt ttgaaatatt
    13141 tctttataca atattgttga agccaagtca ttttctagta aataacgtat ggtagaaagt
    13201 tgatttgagt gtaaaattat atttggctta gctttttcaa gtctttttgt aataatctta
    13261 tagtgataag aaccttcaga taagattaca aaaggtacat tttttaacat ataattcgat
    13321 ataatgggat gttttgccaa ttcatttttg ggatttgtaa ctaagtataa ttctgtttta
    13381 tagattgtct ttgaatctat atcatcataa atatcactgt caattatacc aatacaaaaa
    13441 tcaagtgtag attcttcaat cattttagct ccaacaaatg ttggaacttc aaaaatttta
    13501 agctctatat ctggataaat tacattaaat ctaggaagta tttttgaaag caaaaacgta
    13561 cctaaaactg taggaatacc tattttgaga gaagcttttc tcttttttcc taaatcaagt
    13621 gcgtcacatt gaaaatcctc aaattgtttt ataaaatgtt ttgacttgtc taaaaaaatt
    13681 tttccttcag gcgttaactc tattttatta cctattctgt aaaaaagttc aaagccaagt
    13741 tctttttcta attctttaat tgctaatgtt atggatggtt gagaaatatg aatactttcc
    13801 gcagccttag tcatgttttt atatttacag acagtttgaa aatagtataa atagtttata
    13861 ttcatttggt attagttcct ttcatttaca tattagtgac aagtatataa ttaacaatag
    13921 cataagtttt gtatattgtt gtaaaaaaat agaatagttt taaactatca tagcataagt
    13981 ttttgatatt ttcaatctat taagaatagt gctattatta aattaacaaa agagaatagc
    14041 tggtatggtt tagagtaaat caatctatat tacagttata tcaacgaata tcaaaaaatt
    14101 atctattaga aaataaaaat tatttttaca attaaattgt taattaaatc ataaagaaaa
    14161 aagtgatatt aacaagataa aattttttta atcagaaatg ttaatttaat aacaaaatag
    14221 agtattgggg agaaaggaga aatatatttt ttaataatat ttgttaattt aataacgaaa
    14281 aatgaaaggg agtgatttag tgaagtttga attgatggat tttttaatga atccttttgt
    14341 ccttatgttt gctgcagtaa ttacaggaat tttatttgga aaaattaaat ttgggaagtt
    14401 taattttggg gtatcaggag cattatttac aggattattt attggatggc ttgcatatag
    14461 cttggggaat ctaataatag caaaagggga aacagcagca ggatataagg cagcaactgt
    14521 aatgatgggt aatggaatta tttcttctga cttctttgat ttctttttaa taatatttgt
    14581 tgcagcagtt ggtctattgg cagcaaaaga tatgaaagct gtattaaaga agtatggagc
    14641 aagatttgta attttaggag ttcttataac ttttataggt ggctctatga cttatgcaat
    14701 gactttacta tcaagtgata aaggaagtag tgcttatgaa gtttctggcg tttacacagg
    14761 agcattaaca agttcgcctg gattagctgc tgctttagaa acagctggta aacatgcaga
    14821 agatgtatca aaagaatttg aaaaagcttc aataaaagat aaaaaagaaa ttttaaaagt
    14881 agtcgaccca gaaggcaaat tggatgtgaa tacaactaca tcactgactc aagagcaaat
    14941 agataagtat attgcatatg ctgaagctgg tgttggtata ggtcatgcag tcgcatatcc
    15001 ttttggagtt ttaatagtaa tcttaggtgt aaatttcctt ccaaaattat ttaggatgga
    15061 cctaaaagaa gaaagaagaa aatatgagaa ggaaatgaag gaagcaagag atagtgtttc
    15121 tggtaaaacg ataccagaag ttccatttaa tataataaca tttttcttga catgtttagc
    15181 tggatactta gttggaggaa tacatgtatt tatgggacca ctagggtact tcacactagg
    15241 cgcaacagga ggttcactaa ttgtatctct agttcttgga tatataggta agataggggt
    15301 agtaaatttc agaatggaag aaaaggtttt aaatatttta aaacaaatag ggctagtatt
    15361 tttcttagca atagttggat taagatatgg tggaaaagta gttgattcaa ttatgacatc
    15421 tggtatgcac ctagccttag tagcaatagc agtaggtgtt acagctatga tgataggatt
    15481 cttagttggc aaatacgtat ttaaattaaa ttggatttta ttatctggag ctgtctgtgg
    15541 tggtatgaca tcaacaccag gtcttggagc tgctgttgat gctcttgata gtgatgaccc
    15601 agcagcaggt tatggtgcta cgtatccatt tgcattatta actaaagtta tattggttat
    15661 agttttacac aaacttccaa tgtaaataag attttatatg gggggatatt tatgaataat
    15721 gaaggagcat ttgaagaatt aagtggaaga ttaagaaata aagaattgtg tgatttaata
    15781 atgaatgcag atgaagctgc taaaattata gaggatggca tggttattgg agttagtgga
    15841 tttacacctt caggctatcc aaaagcagta ccattagcag tttcagaaag agctaaaagt
    15901 ggagaaaaga taaaattaac cgtatattca ggagcatctt taggtccaga agttgatgga
    15961 gcatggtcag aagcaggtat aattgaaaga agacttcctt atcaaactaa ttcaatactt
    16021 agaaataata ttaataaagg tgttgttgat tatatagata tgcacctaag tcattctact
    16081 caatttttaa attatggaac tatacctaaa gtagatgtag ctatagtaga agcacttgca
    16141 ataactgaag aaggaaatat tataccaact agtgggatag gtaattctcc atcttttata
    16201 aaaagtgcag ataaagtaat agtagagata aatcttgcaa aaccaatgga aatggaaggt
    16261 atggcagata tatatattac ggaaaatcca ccaaatagaa aaccaataga aataaatcat
    16321 cctaaggata gaattggaac aacatatata ccttgtggtt tggataaaat tgcaggagta
    16381 gtaattacca atatgcaaga taagacccgt ccattgggag ttgtagatga agcttcgaaa
    16441 aaaatatcaa ataatattat tgctttttta agagaagaag taaaggcagg cagattatca
    16501 aagaatttac ttcctcttca atctggtgta ggaagtgtag caaatgcagt attatatgga
    16561 ttatgtgaat ctgaatttga aaatttaact tgttatacag aggttgtaca ggactctatg
    16621 ttggatttaa taagaatggg taaagttaca atggcatcta ctacatctgt aagtccatct
    16681 ccagaaggat taataaaatt tgaaaaagat attgattttt ttaaggataa gattatatta
    16741 agacctcaag aaattagtaa caatccagaa atagccagaa gaattggtgt aattgcaatg
    16801 aacactgcaa ttgaagttga tatttatgga aatgtaaatt ctactcacat aatggggtca
    16861 aagatgatga atggaattgg tggttctggt gattttgcta gaaatggagc aataactata
    16921 tttagtactg agtcaattgc aaaaaatggt gatatatcat caatagtacc tatggtatct
    16981 cacgtagacc acactgaaca tgatgtaatg gtaattgtaa cagaacaagg atatgctgat
    17041 ttaagaggtc ttgcacctag agaaagagct ataaaaataa tagaaaattg tgcccatcca
    17101 gattataaag aacaacttag ggattattta aatagagctt gtaaaagtgg agcaaaacaa
    17161 acacctcaca tattggacga agctttatca tggcatagta aatttatgag tacaggtaca
    17221 atgaaaaagg ctgaaacttt taaaagtgca ttataaaata tttaataaat tggaggtaga
    17281 ttttaaatgg aaaaagcagt ggaaaacttt gaagatttaa gtaaggaata cattaatggt
    17341 tatattgaga gagcaagaaa agctcaaaga gagtttgaat gttatactca agaacaagta
    17401 gataaaatag taaaaatagt tggaaaagta gtgtattata atgctgaata tttagctaaa
    17461 cttgctgtag aagagactgg aatgggagta tatgaagata aggtagctaa aaataaaagc
    17521 aaagcaaaag ttatatataa caatttaaaa gataaaaaat cagttggtat aattgatata
    17581 gatagagaaa ctggaataac aaaggtagct aaaccagttg gagtagtagc ggcaataact
    17641 ccttgtacaa atccaatcgt tacacctatg agcaatgcaa tgtttgcact taagggaaga
    17701 aatgcaatta ttatcacacc tcatcataaa gcaattggat gtagtacaaa aactgtagag
    17761 atgattaatg aagaattaga aaaaatagga gctccagaaa atttaataca aatacttgac
    17821 caacaatcaa gagaaaatac aagaaattta atttcatcag cagatgtagt aattgccact
    17881 ggaggaatgg gaatggtaaa agctgcgtac tcaagtggaa aaccagcact tggtgtaggg
    17941 gcaggaaatg ttcaatgtat catagataga gatgtagaca ttaaagaagc agtacctaaa
    18001 atcatagcag gaagaatttt tgataatggt atcatttgtt caggtgaaca gtcagtaata
    18061 gtagcagaag aaatgtttga taaaataatg gatgaattta aaaataataa aggttttata
    18121 gttagagata aagtacaaaa agaagctttc agaaatgcta tgtttgtaaa taaatctatg
    18181 aataaagatg cagtaggtca atcagttcat acaattgcaa aaattgcagg tgttgagata
    18241 ccagaagata caaaaataat agtaatagaa gctgatggac caggagaaga ggatattatt
    18301 gcaaaagaaa aaatgtgtcc agttatatct gcatacaagt ataaaagttt tgaagaaggt
    18361 gtagctattg caaaagcaaa tttaaatgta gaaggaaaag gacatagtgt atctatacat
    18421 tcaaatacag ttaaaaatat agaatatgca ggagaaaata tagaagtatc aagatttgtt
    18481 attaatcaat gttgtgctac tagtgctgga ggaagtttct ttaatggtct tgcacctact
    18541 aatactctag gttgtggttc ttggggaaat aacagcatct ctgaaaatct tgattataag
    18601 catctaatta atatttctag aattgcttat tatatgccag aaaatgaagt ccctacagat
    18661 gaagaacttt ggggataaaa tttagacaaa aaatattcat tctaaattaa agtaggaata
    18721 tattttaatt tagaatgaat ttaagacata aattaaattt aaattagttt attggactaa
    18781 atttaaaata ttaagagaca tatagaagaa ggaagtatta taatttaaaa taaataaaaa
    18841 aatctataaa agagaaggag tggttttatt atggcattaa tgacaggagc tcaatatatt
    18901 gaaagtttga gaaaattaaa tactaaggtt tatatgtttg gtgaagaggt taagaattgg
    18961 gttgaccatc ctatgattag accatctata aattgtgtag cagcaactta tgacttagct
    19021 catgacccag aatatgcaga tttaatgaca gttacttcaa atatcacagg tgaaaaaata
    19081 aatagatttg gtcatcttca tcaaagtgtt gatgatttga taaaaaaagt aaaaatgcaa
    19141 agactatgtg gtcaaaaaac agcttcttgt ttccaaagat gtgttggtat ggatgcgttt
    19201 aatgcagtgt attcaacaac atttgagtgt gataaagccc atggaactaa ttatcatgat
    19261 aattttgtaa aatacttaac ttatatacaa gaaaacgatt tagtagttga tggagctatg
    19321 actgacccta agggagatag aagtctatca cctagtgctc aacctgaccc agatatgttc
    19381 cttcatatag tagaaagaag agaagatggg ataattgtaa gaggagcaaa ggcacatcaa
    19441 actggttcaa taaattcaca tgagcacctt ataatgccta ctataagtat gactgaagca
    19501 gataaagact acgctgtatc atttgcagtt ccttcagatg ctgaaggagt gtttatgatt
    19561 tatggaagac aatcttgtga cactagaaaa ttagaagaag gtgcagatgt tgatttagga
    19621 aataaggagt ttggaggtca agaagcttta gtagtatttg ataatgtatt tgttccaaat
    19681 gatagaattt tcttatgtgg agaatgggat ttctctggta tgttagtaga gagatttgca
    19741 ggataccata gacaaagtta tggtggatgt aaagtaggag taggtgatgt aataatagga
    19801 gcagcagctt tagcagctga ttataatgga gcaaacaaag cttcacatat aaaagataaa
    19861 ctaatagaaa tgactcacct taatgaaagc ttatattgct gtggtatagc atgttcatca
    19921 gaaggtcaca aaacagaagc tggaaactat caaatagatt tacttcttgc aaatgtgtgt
    19981 aaacaaaatg taactagatt tccttatgaa atagtaagac ttgcagaaga tatagctgga
    20041 gggcttatgg ttactatgcc ttcagaaaaa gactttaaat cagaccttaa agttggaaca
    20101 agtggaatga ctattggcga agtatgtaac aagtatttta aagcttcttc agtggcttca
    20161 acagaagaaa gaatgagaat attaagattc ttagaaaata tatgccttgg ttcatctgct
    20221 gttggttata gaactgagtc aatgcatggg gcaggttcac cacaagctca aagaataatg
    20281 atttcaagac aaggaaacat aaatcaaaag aaagaattag ctaagaaaat tgcgggaata
    20341 aaaaaagagg aagctttaaa tttataaaaa gttgatatat aaagggaaat tatatattaa
    20401 tgtgtgttaa ttaatgaaaa aatatgtagt ataagagata gttataaaat tatggtggtt
    20461 tttagctaag taaagaaatt tttaataagg agaatttaca catgacctgt ggagttagat
    20521 tttgtggggg ctgtaaccct agatacgaaa gagggaaggc tcttacaata atcaaagagc
    20581 acttcaatgg tagggtagat tttagtatag cacaagagaa cgtcgagtat gatttgttac
    20641 ttataattgg aggatgcgca actctatgcg catcctatca acaatataaa gtgaaaaatg
    20701 aatgtgttaa gatgtgggat tttagccata tagaaagagt tataaatgtg attgaatcag
    20761 caatttgtga aacttaaaaa agctaaatgg ggggatttca ttgagttggc aagaattgta
    20821 tcaaagtaaa ttatgtagtg ctacagaagc tgtaaaacag attaaaaacg gtgatactgt
    20881 agtatttgca cattgtgtag gtgaacctcc tgcactagta gaagctatga ttgaaaatgc
    20941 tgaacaatat aaagatgttg agattaaaca tatggtaagc ttgggtagtg gtggatatac
    21001 tgctaaggga atggaagctc attttagagt aaatccaatg tttgtaagtg gaaatgtaag
    21061 aaaggcaatt gaaaatggag atggtgattt tacacctgca ttcttccatg aagtaccaaa
    21121 gttgcttaga gaaaaaagat taaaatgtga tgttgtttta gcacaggtaa ctccaccaga
    21181 tgaacatggg tattgtagct taggaacatc agttgattat acttatgaag ccattaaaac
    21241 tgctagaaca gtaattgttc aagtgaatga ccagtttcct agaacctatg gtgaggtagt
    21301 ccatgtatca gagtttgact atatagtgga aaaatcacaa cctttatttg aactacaacc
    21361 tgcaaagatt ggagaagtag aagaagcaat tggtaaaaat tgtgcttcat taattgaaga
    21421 tggctctact ttacagctag ggattggtgg gataccagat gcagttatgt tatttttaac
    21481 tgataaaaag gatttaggga ttcattcaga aatgatttca gatgggactt tggcccttta
    21541 tgaaaaaggt gttataaatg gtaaatataa aaattttgat aaagaaaaaa tgacagttac
    21601 cttcttaatg ggtactaaaa aattatatga ctttgcaaat aataaccctg cagtagaggt
    21661 aaaaccagta gactatgtga atcatccagc aattataatg aaacaacata agatggtttc
    21721 tataaattct gctatacaag ttgatttaat gggacaggta gttgcagagg ctatgggact
    21781 tagacaattt agtggtgttg gaggtcaagt tgactttata cgtggagtgt ctatgggtga
    21841 agatggaaag gcaattatag ctatgccttc aataactaca aaaaaagatg gtacagtaat
    21901 ttcaaaaatc gtatctattg tggatgaagg tgcacctata acgacatcaa gaaatgatgt
    21961 tgactatatt gtaacagaat acggtatagc agaattaaaa ggaaaatctc ttagagaaag
    22021 agcaagaaat ttaataaata tagctcatcc aagtgtaaga gaacatctag cagtagaatt
    22081 tgaaaagaga tttaaggaga aatattaata atagaggggt gttaataatg gaagcactta
    22141 gagtagttcc aaagatattt tactttgata catttaaaga atttaatgaa gaatttaaaa
    22201 taggaaaaaa tgatttagta attactaatg agtttatata tgagccatat atgaaacctc
    22261 ttggaataga tacaaattta atttttcaag aaaagtttgg aacaggtgaa ccatctgatg
    22321 aaatgataga ctccatgaca aaggaaatga agaaatacaa ttttgataga attattgcat
    22381 ttggaggagg aacaatagtt gatatatgta agatattagc acttgatgtt ccagaaaagt
    22441 ctattgattt atttgaagga gaagtatcac ctaaaaaagt aaaagagtta gtagtagttc
    22501 ctacaacatg tggtacaggt agtgaagtaa caaatgtagc tattgcagag ttaaaatcta
    22561 aacatactaa aaaggggctt gcagtagaag aaacatatgc agactatgca gtgttaattc
    22621 cagagacagt aaaagggtta ccttacaaat tctttgttac aagttcggta gatgctctta
    22681 tacatgctat tgagtcttat ctttctccaa aagcaagtcc atttacagag atgtattctc
    22741 tacaagcaat aaaaatgatt atggatgggt ataagaagat agttgataaa ggagaagaag
    22801 agagatttaa tcatcttaga gactttgtac ttgcatcaaa ttatgcagga attgcttttg
    22861 gaaatgctgg ttgtgcagca gttcatgcac tatcttattc aataggtgga gctttccatg
    22921 ttgcacatgg tgaagcaaat tatcagttct ttactgaagt atttaagatg tattctagaa
    22981 aaaaacctaa tggaaaaatt ataaaatgta caaaaatttt agcagatgcc cttgaatgtg
    23041 accctaactg tgatgtttat ggagaattag aaaagttttt aaataaatta atagctaaaa
    23101 aagctttgag agaatatgga atggtggaaa gtcagataga tgaatttaca gatagtacaa
    23161 tagcaaatca acaacgacta cttgctaata attatgtaga gcttagtaga gaggaaataa
    23221 gagagatatt tgcaaatctt tattaataca attttttatt tatatgtata gtcaacataa
    23281 acaatgctaa ttatatttat gtacaaataa aaataaggga acttaaattt taattaaagt
    23341 taagttctct tatttttata tggagttaaa tataagtata tttttaattt aaaatatgct
    23401 tatatttaag tctattactt tatttgaaac aatttgtaga atttcaaatt ccttgacagt
    23461 aataagtaag taattgtata atcaaactgc aatatattaa taatattagt gaaaatgaaa
    23521 ggattataaa atatgtataa atcagaaaat ttttcaaaaa aatctgtatt aataaattca
    23581 tttttaagta aatttttaaa aataattgga tggggtttgg taagcttatt tacattatca
    23641 gccttagtac tttcaactat ttccattata attggatggg ctgtaatact tcctattcaa
    23701 gtatgtgcag tatttttact tataggagga gtttgtattt ttaaaggtaa gagattagga
    23761 gaccaaattt ctcgttataa aaaatattgt acaattataa acaatagaaa tattattcca
    23821 gtagaactta ttgcagaaaa cacatctaaa tcattaaatt ttataataaa agatgtacaa
    23881 aagatgatag acaaaaacta ctttataaat acttatattg ataaaagaaa taatcagatt
    23941 gtgttaacaa atgaagattt tgttccacca agatatgaag atgtagcata tgaagtcaaa
    24001 gaagaagaaa agactgatga atccaatgaa gttgatacaa ttataaataa aggaatgaat
    24061 tatctaacac aaataaaaga agctaataaa aatattaaat cagaatcaat gggcgataaa
    24121 attgtacaag tagaagatgt tacaagtaaa atatttgatg ttgtaaaaca tgacccatca
    24181 aaacttactc agatacaaaa atttatggat tattatcttc caaccacttt aaaactatta
    24241 aattcatatc atacattgga agaacaagga attgatagag aaaatataac aacaactatg
    24301 gaaagtattg aaaatacaat gaatacgatt gtagtagctt ttgaaaatca attggactat
    24361 ctgtttgaag atgaagccat tgatatttct acagatatta ctgttttaga gaatatgtta
    24421 gtccaagaag gattaacgag tggtaaattt taacttcaat agaaaaaata ttctgttatt
    24481 tttaaacaat taattagtca taaagtataa aatgtgtatt atataagtta atcagtactt
    24541 tatgaaggaa gaggagagaa agatacaatg aataatttag atgatatacc agttatgcca
    24601 actttgacac ttgacccatt tggagaagaa tcaaacacta atgatataga taattctgac
    24661 ttattaatga aaaaggatga aaaagaccca gaagaagaaa aactgtctga atctgaacgc
    24721 aagatggtaa aggaatttgc ggaaaaaata gatattacaa atacaaatat gattttgcaa
    24781 tatggagctg gagctcaaaa aaaggtagca agtttttctg aaacagcttt aaagagtgta
    24841 aaaacaagag atttaggaga agttggagat atgcttacaa atctagttac tgatttaaaa
    24901 gcattttcag cagatgaaaa agaacaaagt ggttttttag gaatttttaa aaaggcaaat
    24961 aataaaattt caaatttaaa aactaagtat gatagtgcag aggtaaatgt ggataaagta
    25021 agcaaagagc ttcaaaagca tcaggttaaa atattgaaag atatagcaat gcttgataag
    25081 atgtatgaat tgaacttagc ttactcaaaa gagcttacta tgtatattat agcaggaaaa
    25141 caaaaattaa aggatatgaa agaatatgaa atgccaaagt tgagagaaaa agctcgttta
    25201 tctggttcaa cagaagatgc tcaatctgta aatgatatgg tttcactttg tgacagattt
    25261 gaaaagaaga ttcatgactt agaattaact agaatggtat cgcttcaaat ggctcctcag
    25321 ataagattgg ttcaaaatag taataatctg atggcagaaa agattcaatc aactatagta
    25381 aataccattc cattatggaa aaatcaaata gtgcttgctc ttggaatttc tcacttaaat
    25441 caagctatga aagcacagcg tgaagttagt aatatgacaa atgagctttt attaaagaat
    25501 gcagaaactt tgaagatggg aacaatagaa acagcaaaag aatcagaaag aggaattgta
    25561 gatatagaca caattaagaa aactaatcaa tctctaatat ctactattga tgaggtagtt
    25621 aaaatacaac atgatggtag aataaagaga caagaagcag aagttgaatt atcaaaaata
    25681 gaaaatgaac ttaaaagtaa gcttcttgaa tttacagtta aataaaaatt atactaatat
    25741 aaaaagagac tgtctcaaaa tagagataag tctctttttc attgtttaaa tgattaaagt
    25801 atatttatat tataaatttc tattatcttt taacataaca tcatgagctc caccttcaac
    25861 tatactagta gaagatacaa gtgtaagttt agcatttttt tgaagttcag gaatgctaag
    25921 tgctccacag ttacacatag tagaacgaac tttacttaaa gaaagagtta cattgtcttt
    25981 caaagaacca gcataaggca cataagagtc aacaccttct tcaaaagaaa gtttcttatc
    26041 tccaccaagg tcatatcttt gccagtttct agcacgagca gaaccttctc cccaatactc
    26101 tttcatataa ctaccattta tattaacttt gttagttgga ctctcatcaa aacgagagaa
    26161 gtatctacca agcattataa aatctgcacc catagctaaa gctaaagtta tatgatggtc
    26221 ataaacgata ccaccatcag agcaaattgg aatataaata cctgtttttt caaagtattc
    26281 gtctctagct tgagcaactt caattataga agtagcttgt ccacgtccta tacctttttg
    26341 ttcacgagtt atacatatag aaccaccacc aataccaact ttaacgaagt cagcaccagc
    26401 ttcagctagg taaaggaatc cttcgcggtc aactacattt ccagctccta ccttaactgt
    26461 atcaccatat ttttcacgaa tgaaatcaag tgttattttt tgccactcag aaaaaccttc
    26521 tgaagaatct atacataaaa catcagcacc agcttcaact aaagcaggaa cacgttcagc
    26581 aaagtctcta gtattaatac cagctccaac tacatatctc ttagaagaat ctaaaagttc
    26641 aagtggattt tctttatgag aagagtaatc tttacggaat accatataca taagattacc
    26701 attatcatca agtacaggaa gagaattaag tttgtggtcc catataatat tgtttgcttc
    26761 ctttaaagta acatctttgt tagcataaac tatagatgac ataggagtca taaattcact
    26821 aactttagta tctaaatcca tacgacttat acgataatca cgacttgcaa caatacccaa
    26881 taatttacca gttgaagttc catcttcagt aacagctact gtagaatgtc cagttttttc
    26941 ttttaagtca agtatgtctt ttaatgtgtt atcaggttta atatttgaat cacttacaac
    27001 aaaaccagct ttgtgggatt taacacgtgc taccatagca gcttcatttt caatagtttg
    27061 agaaccgtat ataaatgaaa taccaccttc tttagcaagt gcaatagcca ttttgtcatc
    27121 agaaacagat tgcataatag cagaagtcaa aggtatattc atataaatat ctgcttcctc
    27181 gcccttttta aatttagtaa caggtgtttt taaacttaca ttagcaggta tacaatcagt
    27241 agaagagaaa cctggtacaa gaaggtattc actgaaagta tgtgatggtg tatcaaaata
    27301 aaacgccatt ttttaatcac tccttatatt tttatacttt ttataattga tagtattaat
    27361 tataacttat tctttaattt tattaaagta ttttgtcaaa tattgagatt tttgaaaaat
    27421 ttaaactatt ttaattaaat ttgtttaata tatattgcct tatagggtaa agttgtatat
    27481 taaataatgt ttagtgttta atagtagcta atttaaaatt aatctttagt
//
LOCUS       DAYAKB010000047        27270 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.047, whole genome shotgun sequence.
ACCESSION   DAYAKB010000047 DAYAKB010000000
VERSION     DAYAKB010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.047"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1339
                     /locus_tag="ACGI3L_002401"
     CDS             <1..1339
                     /locus_tag="ACGI3L_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9198101.1"
                     /translation="FNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLP
                     PKVLSNFMRNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECI
                     QNEKLDLNSDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINI
                     VLISVMCFAGILAIFTAVILSEKIAKPIKELCEFVKKMGQGDFKRTYFDFSDKELVEL
                     STVMNKSAEYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIIL
                     EESDRLSDMVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYE
                     FDEEMVLFECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKK
                     EDLPHVFERFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            1544..3157
                     /locus_tag="ACGI3L_002402"
     CDS             1544..3157
                     /locus_tag="ACGI3L_002402"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9198102.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(3520..4350)
                     /locus_tag="ACGI3L_002403"
     CDS             complement(3520..4350)
                     /locus_tag="ACGI3L_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9198103.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKSACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            4423..6150
                     /locus_tag="ACGI3L_002404"
     CDS             4423..6150
                     /locus_tag="ACGI3L_002404"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198104.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            6187..8049
                     /locus_tag="ACGI3L_002405"
     CDS             6187..8049
                     /locus_tag="ACGI3L_002405"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198105.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            8382..9071
                     /locus_tag="ACGI3L_002406"
     CDS             8382..9071
                     /locus_tag="ACGI3L_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HFG9198106.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            9188..9862
                     /locus_tag="ACGI3L_002407"
     CDS             9188..9862
                     /locus_tag="ACGI3L_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HFG9198107.1"
                     /translation="MTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMVYKKT
                     YMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDPMDLV
                     FLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNEDSEDI
                     ATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAVLVSY
                     NGDYVA"
     gene            9879..11786
                     /locus_tag="ACGI3L_002408"
     CDS             9879..11786
                     /locus_tag="ACGI3L_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HFG9198108.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            12239..12928
                     /locus_tag="ACGI3L_002409"
     CDS             12239..12928
                     /locus_tag="ACGI3L_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9198109.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            13364..13903
                     /locus_tag="ACGI3L_002410"
     CDS             13364..13903
                     /locus_tag="ACGI3L_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9198110.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            13922..14965
                     /gene="potA"
                     /locus_tag="ACGI3L_002411"
     CDS             13922..14965
                     /gene="potA"
                     /locus_tag="ACGI3L_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:1902047 - polyamine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9198111.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            14967..15803
                     /locus_tag="ACGI3L_002412"
     CDS             14967..15803
                     /locus_tag="ACGI3L_002412"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198112.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            15908..16582
                     /locus_tag="ACGI3L_002413"
     CDS             15908..16582
                     /locus_tag="ACGI3L_002413"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198113.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            16582..17634
                     /locus_tag="ACGI3L_002414"
     CDS             16582..17634
                     /locus_tag="ACGI3L_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9198114.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            17864..18712
                     /locus_tag="ACGI3L_002415"
     CDS             17864..18712
                     /locus_tag="ACGI3L_002415"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9198115.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            18702..20366
                     /locus_tag="ACGI3L_002416"
     CDS             18702..20366
                     /locus_tag="ACGI3L_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2334 domain-containing protein"
                     /protein_id="HFG9198116.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            20415..21671
                     /locus_tag="ACGI3L_002417"
     CDS             20415..21671
                     /locus_tag="ACGI3L_002417"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9198117.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            21694..23775
                     /locus_tag="ACGI3L_002418"
     CDS             21694..23775
                     /locus_tag="ACGI3L_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HFG9198118.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIIVMIL
                     SMLYIKKYKRR"
     gene            23812..24897
                     /locus_tag="ACGI3L_002419"
     CDS             23812..24897
                     /locus_tag="ACGI3L_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFG9198119.1"
                     /translation="MRKYMNEFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            24951..26075
                     /gene="wecB"
                     /locus_tag="ACGI3L_002420"
     CDS             24951..26075
                     /gene="wecB"
                     /locus_tag="ACGI3L_002420"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HFG9198120.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            26153..27127
                     /locus_tag="ACGI3L_002421"
     CDS             26153..27127
                     /locus_tag="ACGI3L_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFG9198121.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        10830 a         2704 c         4686 g         9050 t
ORIGIN      
        1 ttttaatgta tttcttgata catatataaa aacaactgcg aatgaagaat tgacaaagtc
       61 tacagaaata gtagaacata tggatagtaa ttttagacct attaagccac cacaagatga
      121 tggaaagctt cctcccaaag tattatctaa ttttatgaga aatgtacaag ataaagttag
      181 gatggcagaa acacaatcag atgctgatgc tatggtagtt gattctaagt ataacctgat
      241 atttccaaca agagaggatg atttcttaaa aaatgttgat gagatggagc tgattaggga
      301 gtgtattcaa aatgaaaaat tagatttaaa ttcagatgaa aatacacgga tatctaccag
      361 aaataaggat tattatattt caactgtaaa aattactagt atatatggtg aacaagacaa
      421 gtatcttata ctttttatag acatatcaaa aactctaaat ctagcacaaa agataaatat
      481 tgtattaata tctgtaatgt gttttgctgg aatattagca atatttacag ctgtgatttt
      541 atctgagaaa attgctaaac cgataaaaga gttgtgtgag tttgtaaaaa aaatgggtca
      601 aggagatttc aaaagaacct actttgactt ttcagataaa gaattagtag agctctcaac
      661 tgttatgaat aagagtgctg agtatctgga taagtatgat aatgaacaaa aaatattttt
      721 tcaaaatgca tctcatgaat taaggacacc acttatgtct attaaaggtt atgcagaagc
      781 tataaaatat aatgttatag atagtaaaca tgcaagtgat ataattcttg aagaaagtga
      841 taggttaagt gatatggttg aagatttatt atacatttct aaaatagata atataactaa
      901 agattttgaa cttgtagaat gtgatttaag agaagtactt tcaaattgtg gagctaggca
      961 aaatgtaaga gctataaata aggggataaa atttatttat gaatttgatg aagaaatggt
     1021 tttatttgaa tgtgatgaaa aaaacatttc caaagcattt atgaatctta tagaaaatgc
     1081 tttgagatac gctaagagtg aaataaaaat agtgtgtaag tataatcaaa aaaatatagt
     1141 tgtgataata gaagatgatg gaattggaat caagaaagaa gatttacctc atgtttttga
     1201 aagattctat aagggagtag ggggaaatca tggaattgga ttatcaatag ttaaatctat
     1261 tgtaaataag catggtgggc gtatatacgt agaaaatggc aaaaaaggag ctaaatttac
     1321 tatattattt aaattgtaaa aaaattagag aaaatataga gatgtttgaa gttgtttttt
     1381 atatatatct gttgtatact gttgaaaaaa gaacaatatt aagctgacat atattacgat
     1441 agttgacatt taaagtaaat gcttaaatat agatacgaaa ggaaaagtaa aatctgaagt
     1501 gtatttaggt ttaagtaagc ttcttatttt ataaaaaata tgtatgaaag aacagctgat
     1561 ttttaatatt acaaatttag taacggttgt atttgaagct tttgtcatcc atatgttttt
     1621 atcagacttt ttaggtcaga aagaagggta tataaaagtt gtaagatatg ctaaactggg
     1681 ttttataata tgtttaggat tctgtaattt aataacttta aaccctaaaa tcacaatgcc
     1741 tttaattttc atccttattt tttcaacatc atttttatat aaaggaaatt taaagacacg
     1801 attgtttact actgttttat taagtatatt ctttatactg tcagaaattg tagttacaag
     1861 tatttttgtt ttatttgtaa aagaaggctt tgaaataatg cttgaaaata atagtataag
     1921 agtattggcg acaattttat ctaaaattgt ctttttgttg acttgtaaaa ttatttgtct
     1981 atttaaaaag gatgtacatt tagatatgcc cataaagtat tggctccctt tatttttaat
     2041 acctatattt agtttatttc tgtctgtttc tatctttgat gtaagtaaat tttttagtct
     2101 tgaaagttta aaatttctaa gcttaatatc tagtgttggt attttatata ttaattttat
     2161 tgtcttttat ttatttaaat ttattataga taaaactaaa ctatctatga aatatgaact
     2221 acttgaaaaa gaaataattc ataaggaaga attaagactt agtaatgagt gttataaaat
     2281 tattgttgaa cagactgatt ctgtcgtttt cgaatggaat atcaaagaaa ataaatcatt
     2341 tgtatcgcag gcttggactg aaaaatttgg atataacaat gcatgtaaga atatttttaa
     2401 agaaattaaa gataaagact tagttcattc tgaagataaa gctatatttg aaggttttct
     2461 tgaaagtatt aaaaaaaaga atatgcacaa tcaagcagta tatcgtttaa aaaaatctaa
     2521 tggtgaatat atttggtgta gaacatcaat tacaagcatt tataatgatg aaaatgaact
     2581 tttaagagtt gtcggagtaa ttgtagatgt agatagtgat ataaaaaaat atgaagagtt
     2641 aagaactaga gcagaaagtg actcattgac caatatatac aataaaggta catttgaaaa
     2701 attagtggaa gaaactatag ttatgaatac aggtgataaa aaagatgcat tattcattat
     2761 tgatttggat gattttaaag aaataaatga taattttggt catccatttg gtgattttgt
     2821 actaaaaaca tttgctgata agatacaaac tagttttggt agtaaagact tagtcggaag
     2881 aattggtgga gatgaatttg ttgtatatat gcaagattat gttacagaag taaatttgca
     2941 taaaaaagct aaagaattaa atagagtact ttcggataat tacactgatt tgagttttag
     3001 ttttgatgct tctgtcagta taggtattgc aaggtatcct caagatggaa cttcattttt
     3061 tgaattgttt aaaaatgcag atagagcact ttatagcata aaagcatcag gtaaaaattc
     3121 atattgttta tttgaagaag aactatatgt acagtgaatt tgaatttaga ttttatgtga
     3181 gagtaagatt tatatatact tgtggctgtc tgatttataa aatatgttac tttgtatatt
     3241 tttatatgtt tcagtaaggt taattaacat gagcaaaggt gtaagtaaat ttatattagt
     3301 ttaagtttac ttacaccttt ataaaaatac aaataataga ttcatttaca ttcttaaatg
     3361 attaaagctc tttaccttct aaacatgcat aacatatcgt tataattcca gtaaataaga
     3421 ctaaaatgcc cattactaag attacaattt catcatctat tactccaaat gtttttaaag
     3481 taacttattt cgctttgtat cataataatt tgtctctttt tacattttaa cttctgctga
     3541 gatttgagtt agatattcat tagaatctcg cacacttata tcatatagaa gatattcttc
     3601 ataaacaaaa tccccaatac gtaaattatt ctgattaaaa aaatttaata acttttcata
     3661 agccttgtaa atagtttcat aactcccttt atgataagca gttacataaa gtccctttgg
     3721 tttgattgat acaggatatt tcttgtactc tttattaact tttgtaaata aatatgaata
     3781 tgattcaaag tctttattaa ttatatcttc acctttaatg attgagccaa tcgtaccata
     3841 atcactcaat tcatagttgt ccataaagtt aatacattca tataaaaaat tttcttcctc
     3901 atctcctaaa aactgttctt tatatgtaac aggtgttttg accaagtact cttcttcatg
     3961 ttcttttaaa gtaatagtat tcgcatctat attacatgca cttttagtaa atgaaatagt
     4021 agattccatt agagcttgaa tattatttag tttttcaatt tcatttttaa tatcaatggt
     4081 tttcttttct aaaagctcaa ttagtaaatt aggtgttctt ttgtctatat aagctttaat
     4141 ttcttttaaa ggcattttta cttccctaag tgaagaaatt ataccaaaaa tgctaagttg
     4201 atggtatgag tagtatctat atccattttc tttctttaat tctggtgaga aaagacctat
     4261 atcatcataa tggaaaagtg tttttttatt gattccacaa atctttgcaa attctccagt
     4321 tgtaaaataa ttttttgaaa cttgactcat aattataatt cctccttgac tatcctgtta
     4381 cagtatagtt tatcatagta ttttgtaaag gagtgtgatt atatgaaaaa attaattcat
     4441 tttttaaaac catatagagt tttaattgtt gtagttttga tatttacgtt tttacaaaca
     4501 cttggaactt tgtatatacc aacacttaca gcaaatatag taaataatgg tgtagtaaag
     4561 ggagatatag attatattgt aaaaacaggt ttaatgatga tgatagtagc tggtataaca
     4621 gctttatcag ctgtgttagt ttgtaaagta tcagcaaatc tttcatctgg attttgtaga
     4681 gatattagag aagcagtatt tataaaatca caagatttat caataaatga ttttaataat
     4741 ataggtacag catcaatgat tactaggagt actagtgata ttactttaat aggtcagtct
     4801 gtgtttatgt ttattcaatt agtattacca gcaccaatta taactgtttc tggtctattc
     4861 ttagcatatt ctatagataa agcaatgaca attattattg ttgtagtaat gtttttattc
     4921 atgctttcag catttttagt tggtaaaaag cttataaagt tgtttaaaat gatgcaaata
     4981 aagatggata atatgaatag ggtgttacgt gaggtagtaa ctggagtaag agttataaga
     5041 gcttttaata ggagtcgttt tgaaaaaaag agatttgata gaactgcaat agattattct
     5101 gaaacagcaa tttcaataaa taaaatattt gcagtactta tgcctattgt aatgttaata
     5161 atgaatttag gtatagtaag tattatttgg tttggtggga tgagagtcag taatggaaat
     5221 atggaaatag gtcatataat ggcacttgtt gaatattgta tcttaatttt attctattta
     5281 atcatgggag taatggtatt tatgtacata cctagagcag gtgcatgtgc agatagagta
     5341 aatcagatat tagatataga acctgaaatt gtagatggaa atggtcataa agatactgtc
     5401 tcagagagag gacatttagt atttaaaaat gtaacctttt catatgcaca atcagaagaa
     5461 cctgtgttaa ataatataac atttgaagca aaatctggag aagtaactgc aattatagga
     5521 agcactggct caggcaaatc tactattgca aatataatac cacgtttttt tgaaattcaa
     5581 tctggagaaa tatctataaa tggtcaggat attaagaaga ttcctcaaaa agaacttaga
     5641 gataagattg gatttgtacc acaaaaagct tttttattta gtggaacaat agaagaaaat
     5701 ataaggtatg gaaaagaaga tgcaagtatt gaagaagtaa agcatgctgc aagtatagct
     5761 caagctgatg aatttattta tgatatggaa gacaagtatg actcatttgt agcacaaggt
     5821 ggaaataatt tgtcaggtgg tcaaaaacag agaatatcca ttgcaagagc gttagttaga
     5881 aagcctgaag tatatgtctt tgatgatagt ttttctgcat tagattttaa aacagataaa
     5941 agacttagaa aagcgttgaa aaatgaaatc aaagattcat cagctataat tatagcacaa
     6001 cgtataagta caatcatgga tgctaatcag attatagttt taaatgatgg aaaaattgta
     6061 ggtattggaa aacataaaga tttacttgaa aattgtgaag tttataagca aattgcggat
     6121 tcacaactta gtaaagaaga acttgcataa aatgaagaat taatctgata tttggaggtg
     6181 tatgatatga gtgaaaaaag aatagatgaa caagatatag aagtacttag ttttgaagat
     6241 ggcatgtcag cagaaaaagc taaggatgca aaaaaaacta ctaagagatt attaaaatat
     6301 atggcaaaac aaaagtttaa aatattaatt atttttattt cagtattgat aagttcagcg
     6361 cttacagttt tagcacctat ggttatggga aaagctattg accaactatt taatggaata
     6421 aaaactgcag tccaaacagg tacaaaattc agtgtgaatt ttagtactat gggagggata
     6481 gtatcaatac ttctagggtt gtacttaatt agtgcagtat ttatatatat tcaacagtat
     6541 attatgtcag gagttgcaca aaatctagtt cttagcatga gaaaagattt aagtgataaa
     6601 ctcaataaac ttcctcttaa gtactatgat tctcataaaa agggggaaac acttagtata
     6661 gtaacaaatg atttagaaaa agtagcagat agtttacaag aaggattaat gcaacttatt
     6721 acagcagtag ttacagtagt tggttctatt gtaatgatga taagtataag tgtaccactt
     6781 acaatagtat cagctataac attacttgtt tcattgggta ttactgttgt aattgcaaga
     6841 aaatcacaag aaagattctc tgaaaatcaa aaggcactag gagagttaaa tagcaatata
     6901 gaagagatat ttactggtca aatagtggtt aaagcattta gtaaagaaaa ggatactata
     6961 agaaacttta aaatattaaa tcaaaatctt tataatgcaa gtagaaaagc acagttttcg
     7021 tcatatgcaa tatctccaat tattagattt ataaacctaa ttggctatgt tattatagca
     7081 gttgtaggtg ggatatttgc atcaactgga gcaatgactc ttggtagtat acaagcgttt
     7141 attcaatatg taaatcaagc atcagagcct actacagaaa tatcttatat tgtaaatatg
     7201 cttcaagcag caatagcatc tgcagagaga gtttttacag ttatggacga ggtggaagag
     7261 ataaaggatg aagaatcttc aaaggttatt agcatgccta aaggtaaagt acaatttgag
     7321 catgttaaat ttggatatag tgatgatttt attcttatga aagatattaa tatcaatcta
     7381 aatgcaggag ataagattgc aattgttgga cctacaggag ctggaaagac aactcttgta
     7441 aatttactta tgagatttta tgagatacaa ggtggaagaa ttactattga tggtgttaat
     7501 ataaaagatt taaagcgtgg agaacttaga actatgtttg gtatggttct tcaagataca
     7561 tggctgttta atggaagtat aaaagaaaat attgcatata gtaagtcaga tgccacaatg
     7621 gatgaaattg taagagcagc aaaatcagca agagtagacc attttataag gactttacca
     7681 caagggtatg acactatatt gactgaggat gcttctaatc tatctcaagg tcaaaagcaa
     7741 cttctaacaa ttgccagggc aatactttca gacccatcag tattgattct tgatgaagca
     7801 acatctagtg tagatactag aacagaggta gaaattcaaa aggcaatgaa taacttgatg
     7861 aagggaagaa ctagttttgt tattgcacat agattatcaa ctattcgaga tgctgattta
     7921 atattagtaa tgaaagaagg aactattatt gaacaaggaa gccataagga acttattgaa
     7981 aagaaaggat tctatgaaga actttataac agtcaattta caagtgaata tgatgaagat
     8041 gttgtatgat tatcaagttt taggcaacta aatgattgat aaatattaag ttaaatatag
     8101 taacatgtaa ggttatatgg aataagagta tttctctatt tcatataacc ttttttattt
     8161 atcaaaataa gataaaattt cctttctaaa ttagattgaa gaatgtattt atcaatataa
     8221 aagtaaaata atcattatta ttagtgaagt aaatattgtt tgccacatat atgccataaa
     8281 gatgcactta ttttacggag atttaacaaa gtagtgtaaa gtatactcta aatataaaat
     8341 aaatcaaata gagttaaata aattgagagg tgatataaat agtgaataaa aaattgaact
     8401 atagatttga aatgaagcac aaaataactg aagcagatgt gttagcttta aaatcaagac
     8461 tctatccaat aatgaagaaa gatgaaaatg catctaaaga tggaaaatat cttattagga
     8521 gtttatattt tgatactcct gaagataaag cacttttgga taaattaaat ggcgttgcaa
     8581 taagagaaaa gtttaggata agattttata ataatgactg ctcttatata aggttagaga
     8641 aaaaaatcaa acattacaac atgacatcaa agctatcaac taatttaacc aaaaaagaag
     8701 taataaatat actaaataat gatattgaat ttctaaaaga gtcgacaaat tgtttattaa
     8761 gagaatttta tttgaaatta aaatgtgaaa gattagaggc aaaaagcata gttgattaca
     8821 atagagaagc ttttatttat ccagttggaa atgtaagagt tacaatcgat agtgatatta
     8881 aaacttctgt aaattcggta gatttattta ataaagattt gccaactatt tcggtaattg
     8941 atgagaatat gactgtattg gaggttaaat atgatgaatt tataccagat tttataaagg
     9001 atttaattca aattaataag actacctcta cagcagtttc aaagtatgct tcaagtagat
     9061 tatatattta agaataaagg ctatgattta tataaagata tacataaata aggttaaaaa
     9121 acaaataagt taaaaataaa taaaataaaa aataaataag ttaaaaatag gaaggatgat
     9181 tttaattatg acatttaatg atatttttaa atcaagtttt atagaaaacg tatcaggttt
     9241 ttcatttgtg gacagtgctt tagcactagg ttcagctttt ttagtaggtt tgtttatata
     9301 tatggtctat aaaaagactt atatgggaat tatgtattct cgaccattca atgtgtcgct
     9361 tgtagcactt acaatgctta caacttttgt aatattggcg gttacttcaa atgtagtttt
     9421 atccttaggt atggttggtg ctttatctat agtaagattt agaacagcaa ttaaagaccc
     9481 aatggattta gtatttctat tttggtcatt aggttcaggt atagttttag gagcaggttt
     9541 gattccctta gctgtcatgg gttcaataat tatgggattg attctaatat tcttttcaaa
     9601 taaaacaata tctgaaactc catatatatt gatggtaaat tgtaataatg aagattcaga
     9661 agatatagca actgataaaa ttaaaaaagt atttactaaa tatcaaataa aatcaaaaag
     9721 tgttacacca gaaaaaggaa tagaattagt gtttgaagta agaatgaaag atggagaaac
     9781 aagtcttata aatgacttga gtcaagtaga tggagttact aatgcagttc ttgtaagtta
     9841 taatggtgac tatgtagcat agagaggagt aatcttttat gaaagataaa aaatttaccc
     9901 ttcttatctc gattatgatt atatttttat gtgctgtagt tggagtttat agtacatcta
     9961 gcaacaaaag tgctgattta tatagtgatg tatatattga aaaatatttt aacagagaca
    10021 aggttatgga agttaatata gagatagatg aaagtgactt gaaggatatg aatgaaaatg
    10081 ctataaaaga agaatttaag gttgcaaaag taactgtaga tggagataca tatggaaacg
    10141 taggtataag aactaaagga aattcaagtc ttatatctgt agcaaatagt gatagtgata
    10201 gatacagcta taagattaat tttgataagt ataatactag tcaaagtatg gaagggctta
    10261 ctcaattaaa tcttaataac tgttactctg acccatctta tatgagagag tttttaacat
    10321 atagtatttg cgaggaaatg ggattagcga ctccagaatt tgcatatgct aaagtctcta
    10381 taaatggcga atatcatggt ttgtatttgg cagtagaagg attaaaagag tcttatcttg
    10441 aaaataattt tggtaatgta actggagact tatataagtc agatgaagga agctcgttgc
    10501 aatataaagg agatgaccca gaaagttact caaacttaat cgttgaaagt gataaaaaga
    10561 cagctgattg gtctaaaatc acaaaactat taaaatcttt ggatacaggt gaagatattg
    10621 aaaaatatct tgatgtagat tctgtcctta aaaatatagc aataaataca gctttattaa
    10681 accttgatag ctatcaaggg agttttgccc ataactatta tttatatgag caagatggag
    10741 tattttctat gttaccatgg gattttaata tgtcatttgg tggatttagt ggttttggtg
    10801 gaggtagtca atctatagca attgatgaac ctacgacagg taatttagaa gacagacctc
    10861 tcatatcctc gttattaaaa aatgagacat acaaaacaaa ataccataaa tatctggaag
    10921 agatagtaac aaaataccta gattcagact atttagagaa tatgacaaca aaattgcatg
    10981 acatgatagc atcatatgta aaagaagacc caacagcatt ttatacttat gaagaatttg
    11041 aaaaaaatat aacatcttca attgaagatt ctagtgataa taagggattt ggtaataaag
    11101 ggtttgacaa caataactct aataacagtg attctaataa taattctaat agtgaaaata
    11161 agcgctctgg aaatcaaagt gatgaaaaag aagttaatgc tgaattaaca tcaagcgtag
    11221 tcaaagctaa tacagataat gaaactaaaa ataaaactac aaatgatagt gaaagtaaga
    11281 ataatacaga taaagataaa agtggaaatg ataataatca aaagctagaa ggtcctatgg
    11341 gtaaaggagg taagtcaata ccaggggttt tggaagttgc agaagatatg agtaaaacta
    11401 taaaatctca attaagtgga gaaacttctt cgacaaagca aaactctggt gatgaaagtt
    11461 caagtggaat taaaggtagt gaaaagtttg atgaggatat gagtggtatg ccagaaccac
    11521 ctgagggaat ggatggtaaa atgccaccag gaatgggtaa tatggataag ggagatatga
    11581 atggtaaaaa tggcaatatg aatatggata gaaatcaaga taatccaaga gaagctggag
    11641 gttttggcaa tagaggagga ggctctgtga gtaaaacaac aacatacttc aaattaattt
    11701 taggtggagc ttcaatgata ataatgtcga ttatgttagt tggtgtatca agggtaaaga
    11761 gaagaagatt tataaagtca aaataagatt aaaattgaat ataaataatt ttaatactgt
    11821 taagtctaaa tatttactta gcagtatttt tttagaaaat aatgtatttg gttaataata
    11881 taaggtaata aattgataaa aattaaatac agcatattaa taatacataa taaagtaata
    11941 aaaaaactgt ttaagtataa taacttatat ttagacagtt tttttcattt ataaataata
    12001 taaatgaaat tgaaaacatt tgaaggatag aaattggttg gataaatgta taaattactt
    12061 caccaaaaaa taatgacaaa aattgtaact aagttgtaat aaaatggtag ttatttagca
    12121 taaaataatg tatcatagaa gtatattata aaattaataa aataagattt ttgtaagaaa
    12181 actgctggct tttgatattt agagtgagta gttaaattat gtttaggagg ggtagaattt
    12241 gttgcaaaaa gtattatgga aatttttaaa gctagtagtc ggtttattta tatgttcagt
    12301 tggtatagta ttgacgataa attgtaacct tggattatct ccctgggatg tatttcatca
    12361 aggactttca aatcatatag gaataactat aggaactgct tctataattg taggctctat
    12421 agtagttatt gctgatgtcg ttcttggaga aaatgtagga tggggaactg tttttaacat
    12481 gctactaatt ggattcttta tggatttact tttatatagt aatttaattc cagaggctga
    12541 tagtttattt gtaggaataa ttatgttgat attaggattg gttcttttgt ctgttggaat
    12601 ggtattttat atgggaagtg gtttaggaag tggacctaga gatggtttga tggttgcaat
    12661 tcaaaagaaa acaggaaaat cacttaaatt aataagaggt actatagaag ttggagcatt
    12721 aatagtagga tttttattag gtggaaaagt tggtatagga actataataa gtgcatttgg
    12781 attggggtat ttcacacaaa tggtatttgg cttatttaaa ttagattgta gtaagattaa
    12841 acatagattt atagtagatg atataaaatt tatcaaagtg tatatgagtg gtgagaaaaa
    12901 agctgctgtt caaaatatag ttaagtaatt taagaataaa ttcaacgaaa tgttaagtat
    12961 tttaaattaa cattttgttt agatagataa attgaatatt aaaagaatat taaaatatga
    13021 ggattgctag aacactataa aatatagatt tctagcaatt ttttatttgt tcaatatttt
    13081 tttagtacta gaagtcttat tctctattta atgaatgaat taatttataa ttagagatac
    13141 taaactttat agatattaat ataaacacct ttaaactgtg tattttccaa agcctttaaa
    13201 atgcttgtat ttattctaaa taaaaaaata aaaaaatgtc aaaaaaactc ttgtattata
    13261 tccaaatttt atatataatt acctatgttg tttagaaatt ttaaactcaa tgtttagtaa
    13321 acaaaatgtt tagtaaaata aaacagaaac taggaggtgc aacatggata taggtgaaaa
    13381 gataaaaaga ttaagaacag aaaaacaact gacccaggaa gagttagcta atagatgtga
    13441 attgtcaaag ggatttattt ctcaattaga aaataactta acatcaccat ccatagctac
    13501 ccttatagat atacttgaaa tactaggtac aaatttaagg gaatttttta atgaaataga
    13561 tgatgaaaga atcagtttta caaaagaaga tatgtttgaa acagaagatg aagatttaaa
    13621 atataaatta aagtggttaa ttccaaattc acaaaaaaat gaaatggagc caataataat
    13681 aacattgtat ccaggaggac agtataaaga agaaaagcca catgaaggtg aagaatttgg
    13741 atatgtatta gcaggttcaa tatatgtcca tataggcgaa aagaaaaata aagtaaaaaa
    13801 aggagagagt ttttacttta gaccgaaagc aaatcactat atatcaaacg agggcaaaac
    13861 tacagcaaaa gtgatttggg taagtacgcc accatcattt tagaatagag gtgtttaata
    13921 attggtagaa aatataatag aattaaggga tatatctaaa cattatgaag aacttactgt
    13981 tttagataat ttcaatttag atataaagaa aaatgagttt ctaacattac ttggaccaag
    14041 tggatgtgga aaaactacaa cattaaaaat aatagcagga tttgagtatg ctgatgatgg
    14101 taaagtttta tttgaaggta aggagataaa taatttgcca ccatatgaaa gacaagtaaa
    14161 cacagtattt caaaaatatg ctttatttcc acacatggat gtttatgaaa atgtagcttt
    14221 tggattaaaa attaaaaaga ctccaaaaga tgtaatagat gctaaagtaa aagaggtttt
    14281 gaaacttgtt gcactagaag gttttgaaag acgacaagtt gaatcattga gtggaggaca
    14341 acaacaaaga attgcaatag caagagctct agttaatgaa ccaaaggtat tattactaga
    14401 tgaaccactt ggagcacttg atttaaagtt aagacaagag atgcaaatag aattaaagag
    14461 aatccaaaaa aaattaggaa taacatttgt ttttgtaact catgaccaag aagaggctct
    14521 tactatgtca gatactattg ttgtaatgta taagggcaaa attcaacaaa tgggaacacc
    14581 acaagatata tacaatgaac ctaaaaattc atttgtagct aagtttatag gtgaaagtaa
    14641 catatttgat ggaattatga tagaagatta taaagttaat ttctgtaata gagattttga
    14701 gtgtgttgat aaaggattcg aaaaaaacga aaatatagaa gtagtaataa gaccagaaga
    14761 tataaaaatg gtaaagccag aagaaggaat gttaaagggg aaagttacat ctacagtgtt
    14821 taaaggagtg cattacgaga tagaattgaa tgaaaatgga agattgtgga tacttcataa
    14881 tactaaaaat gctgaggttg ggactgaact aggcatggat atatatccag aagatatcca
    14941 tataatgaga aaagagaata actaagatga aaagaaaatc ttttttagca tatccatatg
    15001 tagtttggag tgcgatattt gtaataattc ctttaatatt agtagtattt tttagtttta
    15061 caaaagaatc aggtggaggt tatgccttta cacttgagaa ttataaagaa gtaattgacc
    15121 ctatatatat gaaagttttt gggcgttcta ttcttttagc aggaggagct acattaatat
    15181 gccttatagt tggttatcca gtggcatata taatttcaaa ggctcgtgta agtagaagag
    15241 gttcattaat attattgttt attcttccta tgtggatgaa ctttctttta agaacatatg
    15301 catgggttgc tatattagga aaaaatggac ttttaaatac atttttaggt tggtttggaa
    15361 tacaaccatt agcaattttg tatactaatt ttgccatact tttaggtatg gtgtataact
    15421 ttttaccatt tatggttctt ccaatatata cagcactatc aaagatggat aatgatttga
    15481 taaacgctgc tcatgacttg ggtgcaaata atatgacagt ttttagaaaa attatatttc
    15541 ctttgagttt gccaggtgta atgtctggaa taactatggt atttatgcca gcagtcacta
    15601 cttttgcaat atcaagactg ttaggtggag gtaaaataat gctggttgga gatttgattg
    15661 aacaacagtt tacagttgtt ggagattgga actttggttc agctatatcg atatttatga
    15721 tgatagtaat attaatatct atgtctataa tgtcaaaatt tggagatgaa tctgacaaag
    15781 aaggcggtgg gttactattt taaaattaaa gaaaataact tctaatatat atttagcatt
    15841 agtattctta tttttgtatg cacccatatt tgctttggta ctattttctt tcaatgattc
    15901 aaaatcaatg gcaagatgga atggatttac atggaagtgg tatggtcaat tacttcaaaa
    15961 tgagagtata atgagtgctt tatattatac tattgtaata gctatattag cgtctgtaat
    16021 atctacaata gtaggaacta taagtgctat aggaatacat aagatgagag gtaagagtaa
    16081 gaaattaata ctaaatgtaa actatcttcc tattttaaat acagagatag ttacagcagt
    16141 agctcttatg agtctgtttg tatttgtaaa aatggaattt ggatttacaa caatgctatt
    16201 ggcacatata atgttttgtt tgccatacgt tatactttca gttttgccaa aaatgaagca
    16261 attacctgat aatatagaag atgcagctat ggacttggga gcaacaccta tatacgctct
    16321 tagaaaagta attttaccac aaataaaacc aggtatagtt tctggatttt taattgcatt
    16381 tactatgtca atagatgact ttataataag tttctttaat gctggaaatg gtgtaagcaa
    16441 tctttctata gaaatctatg gaatggctag aagaggtata aaacctgaaa taaatgcatt
    16501 atcaacaata atgtttgcag tggttctagg tttactttta ctagctaata aaaaagaatc
    16561 tatagtaagg gggattaaat aatgattaag tttaaaaaag caatatccct tatagctgta
    16621 ggtatgatga cagttacttt atttacagga tgtaataaag caactgattc tacaaaagtt
    16681 ttaaatgtat ataatgttgg agattatata gatgagtctc ttatagataa gtttgaaaaa
    16741 gaaacaggaa tagatgttca atattcaact tatgatacta atgaaatgat gtatcaaaaa
    16801 gtaaagagtg gtagtacaca ctatgattta gtatttcctt cagactatat ggtagagaaa
    16861 atgaaaaatg aaggtctttt ggaaaaatta gattttaaga atatacctaa tatgaaatat
    16921 ttagataaga gttttttaaa tcctgtatac gacaaaacta atgaatatag tgttgcatat
    16981 atgtggggaa ctcttggaat actgtacaat aagaaagaag ttaaagaccc tatggatagc
    17041 tggaatatac tttggaatcc aaagtataag ggaaatataa tgatgtttga ctctgttaga
    17101 gatactatag ggataactct taaaaaatta ggatatagca tgaatagtgt aaatccaaaa
    17161 gaaataaatg aagctaaaaa tcttttaatg aaacaaaagg atttagtatt ggcttatgta
    17221 aatgatgaag gtaaggatag attgcttggt ggagaagtgg caatgggtat gctgtattct
    17281 ggagatgcag ttacactaat ggagcaaaat cctgaccttg attatgctat acctaaagag
    17341 ggaactaata aatgggtaga tgctatgtgt gtacctacaa cagcacaaaa taagaaagaa
    17401 gctgagctgt ttataaactt tttattagac ccagagaatg caaaagtaaa tgctgagtac
    17461 attgggtatt caacacctaa tacaggagca ctaaaattat tagacccaga aataactcag
    17521 aatcctgttg catatccatc taaagaagtg cttgataaat gtgaaacttt tgaagatatt
    17581 ggtgaaaata taaaattata tgacaaggct tggatagagt taaaatcaaa atagggtctt
    17641 gttggtttaa gtaaatttac ttaataaata cttaataaaa ctgttctttt ttagaaaatt
    17701 tattttctaa ttattgaaca gttttatttt ttgtttaagt tatattcata tgcaatttaa
    17761 atagtttatt aataaatgaa aacttatttg tataatgact ttaataataa ttagaaaaaa
    17821 tgggcaactt aatagaataa ttggaggtgt aaatttataa aaaatgaata ggataaataa
    17881 aaaaatagat ttattaatat tggctttgct cgtttttata tttttaattg ttggaatagt
    17941 aatactatcg attaggacag aaaataaatt gaatgtgttc ataatgttag caataatttt
    18001 ttttataata atgttaactt atttatcaaa ttcagtagtg gggttgataa caagttcaat
    18061 aattatattt atgtatacat cctatatttt atataacaat attactcaca atatggatgt
    18121 tgaatttata tcatatatgt ggataatagc aacaccagta tcttcaatta taatgggtaa
    18181 tctgaacaaa agcataaatg aattgcaaaa tacaaataaa aaactatctg aacagtataa
    18241 ggaattagtg actattgata gtgaaactgg acttagaaat ttaaagattt tttataatga
    18301 tgtaaatatg gagataagta aatctattag acataatact gatttttctc ttatgatagt
    18361 aaaattacca tactacggaa acctacagac tatatttggt gaaaacaaaa ctaataaaat
    18421 agtaaaatat attggttcaa atattataga atgtacaaga aatgaagata taatttatag
    18481 tttacaaaaa gatatgatag ggatactaat gccaaataca tctttggaag gttcaaaagt
    18541 tgttaaagac agaataaaga aaaggataaa agaattaaat ttagatttaa acaatagggg
    18601 aaaatatgta aatatagatg tcaaaattgc atttttacaa tataagagta gttttggaga
    18661 tagtataaat tttaagaata tagttgaaga ggaacttcaa tatgatgttt aaaatattta
    18721 ataaaagtct attaaaatta gtagttgtat tatcaatagt actgacaata tcaaatttta
    18781 gcttatcttc atatgcatca gaaattactt ccagcacaga taaggtatta atcatatatg
    18841 attctaagaa agaaacagct tataatagag atattttaaa tattatgagg actctattgg
    18901 gaagatttag ttcagatata gagctattaa aattgagtaa ctatgatggt gagataaata
    18961 aaaattatta cagtcatata tttattttag gaatcaatga aaactcatat aataatgata
    19021 aaaacactaa aaacttgatt agttccttaa atttatataa aggaactata tgttggttag
    19081 gatatggtat agaaaatctt ttggaacata aaaaatacaa tttagactat gtaggaaaaa
    19141 caaacaatat agttagtgta aattatagag gtaaatcata taacttggat gaacattatg
    19201 tttttaacat tgtagaatca aaagatacaa gtaataaagt aataggaagt attaatgata
    19261 ccttaaataa gtatccatat ataataaatg ataaaaatct tttttatgta tcaaaattag
    19321 atttagatgg agttttattt tatatatttt gcgattcact taatgatatt tttaatatta
    19381 agacgtttga taaaggacgt atatttgtaa gaatagaaga tgtacatgct tttagagaac
    19441 caaaaaatct tgtagagata gcggattatt taagtagtaa gaatatacca tttacgattg
    19501 cattaatacc agcatatgta aatcctaaaa atcataaggt aataacttta tcagaaagcc
    19561 ctgaaattgt caaagcaata aaatatatgc aagataaagg tggaactgtg atattgcatg
    19621 gatatactca tcaatacaag aaagaagaag tttctggaga agggtatgaa ttttgggatg
    19681 gtaaaaaaga tgaaccctta aaagaaaata tgaagatatt tgtcaaagat agagttttga
    19741 atggtcttag agtatgtata gagaatggaa tttatcctct tgcatttgaa gcgccacatt
    19801 atgcaatgga atcagaggga tataaagaat taaaaaaata tttttctact tatatagggc
    19861 aacatcaaaa taatgataaa aaatttagca caaatacata tccttatatt attagggata
    19921 cagaggagtt taatatattt atacccgaaa atttaggata tatagaccca gaagataagt
    19981 ttacttttca aaatataaaa gaaaatttag ataaattatc cattgtaaga ggttttagtg
    20041 gagggttctt ctttcattca tatttaaaca tagagtatct aaaaaacaca atagaatatt
    20101 tagaaaaaca gaatatagaa tttatgaatt taagagattt taataattgg gtaaaagttg
    20161 atgaaataca aataagaaat aatggagatg aaattatagt caactatgat aaggacttag
    20221 atgaactaac taaaagtgat actagattta aatccatatc caatattagt aaagttttaa
    20281 tattcatagt atctataagt gttttaatat ttgtgattat atttatatat tttaagagaa
    20341 tagataaaaa gaaattttta aaataaagga ttttatatta gaatcaatat tttaaaatat
    20401 tttaggagaa atttatgaga gatttaaatg tatcagagta tttgttcgta tttagtttgt
    20461 ttagtatatg gtctttattg cttataaata ttattttagc tatgggtgga tatatatttt
    20521 attttaaaaa ctttgataaa gaaataaaag aaattgatga atatcctatg atatcaatac
    20581 ttgttcctgc tcataatgaa gctaaagtga taggtagaac tgtggagtct ttgctattac
    20641 tcaattatcc taagagtaag atggaactta ttgttataaa tgacaattct tctgataata
    20701 gtaaagaaat tttagaaaat ataaaggata ggtacaacaa ttataatttc actataataa
    20761 atacagatag tttaacaggt ggaaaaggaa agtctaatgc attaaatatt ggatatacga
    20821 tttcaaaagg agattttata gctgtttatg atgcagataa cacaccagat aaaaatgcac
    20881 ttagatatct agtacaaact atagtaatga atgatgaatt aggtgctgtt attgggaaat
    20941 ttaggactcg aaataaaaat aaaaacctat taaccaaatt tataaatata gaaacattaa
    21001 gctttcaatg gatgtcacaa gctggtagat ggcaactttt taatctatgt acaataccag
    21061 gaactaactt tatattgagg agaagtatca tagaagaaat tggaggatgg gatagtaaag
    21121 caattgcaga agatacagaa ataagtttta ggatatataa attgggatac aagataaagc
    21181 ttgtaccaca atctataaca tgggaacaag agccagaaac tgttaaggtg tggataaagc
    21241 aacgtactag atgggcaaaa gggaatatat atgtattaat gaaatatata aaaaatatat
    21301 ttaaacaggg aagaaataag attgtgtttg atatagctta ctttttttct gtatattttc
    21361 tatttttaac atctgtaatt atatccgata ttttatttgt tttaagtata tctaaactag
    21421 tagaaatttc tattccaatt aacttttttc taatatggat actatcttat cttttattta
    21481 ttatagaagt gagtataagc cttactatag aaaaaggtga agcaacaatt gaaaatatat
    21541 tcatagtggc aataatgtat tttacatact ctcaactatg gctgtttgta gctataaaag
    21601 gaatgataga gtatctaaaa gatataattt ttaaaagaga ggttaaatgg tataaaacag
    21661 aaagattttg attcatgtac aggaggaatt aacatgaaaa aatttattat atcaattata
    21721 tctttagtat tgtttttttc aaatatatca cttatataca aagtaaatgc tgatgagact
    21781 aaagttaaaa attataagtt tgaaagagat ataactattg atggtgttat aggaagtaat
    21841 agtacttttt ttgaagtaaa taaaaattgg gatattgaag aagttttatt gcatcttaat
    21901 tttagtaaga gccaaatatt aaatggagat gtttcaagtt taactgtatt gataaataat
    21961 gtaccaataa aatctattaa attaaatgct aagacaaatt ataaaaatac attagaagta
    22021 ttagttccaa aagattatat aattcaagga tataatgaaa taaaaataaa aacatacaaa
    22081 acaatatctg ataaaatttg ccaagatgat tccaatactg ggaactggat ggttattcac
    22141 aaagaatcat atatatcaat tagatataag cagaaaaagg tggaaaactc aataaatgaa
    22201 tatccgtatc catatgcaga aattgaaaat aatcataaat tagatacaac tatagtagta
    22261 ccagataata tgactagagg agagactaca gcagtgttta atttggcatc agcatttgga
    22321 aaaataacaa aaaatgatga tttaaagtta gatgttaaat tatattcaga aatgaaaaat
    22381 tggtcagatg ataatattat atatattggt aaacctgaaa atacagcaga agaaattttg
    22441 gatattttaa gtataaagga acaaacccta ttatcttcaa actgtataat caagcaagta
    22501 gattcaccat acaataagaa taagaagatg atggtggtaa ttggtagtaa tgaagatgat
    22561 ttaataaagg catcaaattt attaatagaa aatagacttt ctaaccaagt tttatcatca
    22621 tcagtacttg taaacaaaga gactaatata aaaattaata gggaacaaaa attaaattta
    22681 ggtcatttaa cattaaaaga tttaggatat tctgactttt tgttggaagg agcatttaat
    22741 caacaagctt tgtttgatgt caaaatacca acgggtaagg tattagatga tggttcaaag
    22801 attatcttaa atttaagata ttctgacaat ttagattttg aaaaatcttt agttacagtg
    22861 tctataaatg atgttattgt gggaagtaaa aaattggata ggtcacattc taataatgat
    22921 aagttagaat taaaaatacc taaagatata gataataaaa actattatca agttaaattg
    22981 acatttaatt tgagtataaa aaattcgaat tgtgttacta gagagagtaa taatccttgg
    23041 gcatatgtat caaataattc ttatttggcg ttatctacga aagaaaatga aaccttatct
    23101 tttgaaaatt atccgtatcc atttgttaga gatgatgaat ttaatgattt aactgtgata
    23161 atgccagatt attcagggtc acaagctatg acctggatgt ttagattagg tgttacttta
    23221 ggtgcgaata taaattcaca taatggaaat ataaatgtaa ttagaggaaa agaatttagt
    23281 gacaagtata aggatactaa tattgtagtt tttggagtgc cacataataa ttctgttata
    23341 aagatgttaa ataataattt aaatataaag ttcgataaaa attactccaa ttttatatca
    23401 aatgataaga taagctttat tgatgattat ggaaaaaata tttctactat tcaattaata
    23461 aaatcaccat ataataatca aaaaaatatc atggtaatta gttcaatgaa tgaaaaaaac
    23521 ttatatttag gaatggatta tttgttgaat aaaagtaaag ttaatgattt aaaaggagat
    23581 acattgataa ttgatgaata cggagaggta gaagatttag cttataattt aaaatctaag
    23641 aaagaagtaa aagattcaag ttggaatatg agtataaata agacaactaa agtattttta
    23701 atgatttctt ttattactat aattatagtc atgatattat caatgctata tataaaaaaa
    23761 tataaaagaa gataatatga taaatttatt attttaaaag aggtatataa tttgaggaaa
    23821 tatatgaatg aatttaaatt aaaaagaagt attttaatct cattaataat cttaattttt
    23881 atatttatag tttactttgt aagtattgag ttaaaagata ggagtctagt aaataatcaa
    23941 tataaaggta agattaaatc ggccaattta tctgtagatt atgaaataaa tcaagttatg
    24001 aaggatatag ataaattggg attgaataca gtaaatgtac ctataattat aaatgtagag
    24061 tccattaatt ctgatattat gtcaatagat aataatagta aagaaaaggc aattaagtta
    24121 ataaaaaaat taaataaaaa aggtatttca acaatattag aggcatatcc atggattgaa
    24181 aatggaaaat tgtatgagac tgactggaac cctataaata aaaaaagatt tttttatact
    24241 tggcaaaatg ccatattaaa tgaacttata attgatgtag caaatccact ggatgtaaat
    24301 gttttaaata ttggttctaa ttttgtacat ttggaagaat atcaacaaaa ttggggtgaa
    24361 ataatagatt ttgtacaatc caaatttgac ggtcttgtaa cgtacagaac taattggtgg
    24421 tatacaaaaa aagatgattt aagtagtaag ttgttttatg aacaaaagct gaacaataat
    24481 ttttttgata agttagattt tatatctata gcagcatatt ttgagttaag taataaacct
    24541 gttaatacag tggatgaatt aatttctgcc ttacactcat ctactgtaaa caatagagga
    24601 caaaatataa aacaagaaat atataacctt tataaagctc atagaaaacc tatatttttt
    24661 ggagaattag gtttttcaaa tagagaaagt gcaagttctc agccgtggaa tcatactcct
    24721 tcaaaagctg taaatggcga agaacaagca aggtgttttg aggcatataa gaaagttttt
    24781 gaaaatgaag actggataaa tggtttttct gtgttttgtg taggtaaaat agatgacgaa
    24841 aaaaattttt acccatcaaa agagagtata aaagttatta agtcttggta tgaataattt
    24901 tgaaagtgta gaatttatat agattaaata gatgattagg agagatataa atgaatgaca
    24961 tcaaggttat gactgtattt ggaactagac ctgaagctat caaagtagca cctttaataa
    25021 aggaacttga aaaaagagag aatataaaaa gtattgtttg cgttacagct caacatagag
    25081 aaatgcttga ccaagttata gaaaccttta atataaatgt agactatgat ttggatataa
    25141 tggaaaaagg acaaagcctg aatgatataa catgtaagat tttaaataaa cttcccttga
    25201 ttttaaacaa ggaaaatcca aatataatat tggtacatgg agatacaacc acaactctag
    25261 ctacaagttt gactgcattt tataataaaa ctcttgttgg tcatatagaa gctgggctta
    25321 gaacctatga taaatattct ccttttccag aggagctaaa tagacaactt acaggtatta
    25381 ttgctgatat gcactttgct cctactaatt tggctagaaa aaacttgatt tctgaaggaa
    25441 aacctaataa taatatattt gtaactggta atactgctat tgatgcttta aagatgacaa
    25501 taaaagaaaa ctataatcat cctataattg atgagattgg taacgatagg atgattttgt
    25561 taacctctca cagaagagaa aatttgggta aacctatgaa aaatatattc agagctataa
    25621 agcgaatagt agatgacttt gaagatgtac agatagtata tcccatacat ttaaatccta
    25681 aaatacgaac tatagctgat gagatatttg gaaaatttcc tgaaaaaatt catattatag
    25741 agcctttaga tgtagctgat tttcataact ttttaaataa atcttatatg ataatgactg
    25801 atagtggagg aatacaggaa gaagctccat cattaggtaa gccagttctt gtgttgcgtg
    25861 ataaaacaga aagaacagaa ggaattgaag caaagacact taaattagta ggtactaatg
    25921 aagatagaat atataattca gtgagcgatt tattaataaa taaagataac tatgttcaga
    25981 tgagtaaagc atctaatcca tatggagatg gaaatgcaag caaatatata gtggatataa
    26041 taattaaaaa atttaattgc aaatatttaa attagataag gcctaaaaca ttaactaatt
    26101 gatataagat ttatgataat attaaggaat acaattttta agggggagta atatggctag
    26161 aaaattaata aaaaatttgg gtaaaagtaa aagtgtaaag agagtgaaac ttttatttaa
    26221 gaagattttt attactgtat tcatagtagc aagtatagtt gctattttta atataacgaa
    26281 atattttgag gaattataca aagtaaggga tttaaaaagt actaaaattg aatactatat
    26341 ggatgtggct gatgaagcag gagatggaaa ggtccaatta agttggaagg ccttacttgc
    26401 tatagacatg gtaatacatg atgaagattt aagtaatata aaaaagaaag acacattgga
    26461 tataggggaa aagtttatag tagaagataa aaatggtaaa ggcgaaaagg tgtataaggt
    26521 aaaaaagttt aataaggtat taagcgaatt gaaatttgac tcttctcaaa aaagtagagc
    26581 aagaaaatac atgaaagatt tagaatacac ataccttgga aataaacaat tagatagtag
    26641 tgatgaaaaa attaaattta taaagaagtt agaagactca gctataagag aatatattga
    26701 ttatggaata ttgccctcta taacaattgg acaagctata ttagaatctg gttggggaaa
    26761 ttctaaactt acaaaacaga gtaataattt atttggtata aaagcagata aagcatggaa
    26821 aggaaaaagt gtagaaattt caacttcaga gcattataat gaaaaaattg tagctagttt
    26881 taggtcgtat aattcattac aagattctgt caaagaccac agtttatttt taattaataa
    26941 taaaagatat agaaaacatg ggttgtttga ggcaaaagat tatattagtc aagctcaagc
    27001 attagaaaat gcaggatata gtacagcaga agataaaaaa ggaaatcgta tatatgcaga
    27061 gctattaata gatgttatta ggagttataa tttgcaattg atagataata aagttgagac
    27121 aaaataattg ttaactttat atgaggagat aacaagataa gatttttttc tacaaaaaga
    27181 atagaaaaat tgtaaaaaaa actaaaaaaa tgtattgact tgttatttaa aaggtgatat
    27241 tattattact gtactcgaaa gagaacaaaa
//
LOCUS       DAYAKB010000048        26914 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.048, whole genome shotgun sequence.
ACCESSION   DAYAKB010000048 DAYAKB010000000
VERSION     DAYAKB010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26914
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.048"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..611)
                     /locus_tag="ACGI3L_002422"
     CDS             complement(<1..611)
                     /locus_tag="ACGI3L_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9198122.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDK"
     gene            1082..1732
                     /locus_tag="ACGI3L_002423"
     CDS             1082..1732
                     /locus_tag="ACGI3L_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HFG9198123.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(1872..3248)
                     /locus_tag="ACGI3L_002424"
     CDS             complement(1872..3248)
                     /locus_tag="ACGI3L_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9198124.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(3264..5177)
                     /locus_tag="ACGI3L_002425"
     CDS             complement(3264..5177)
                     /locus_tag="ACGI3L_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9198125.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            5313..5945
                     /locus_tag="ACGI3L_002426"
     CDS             5313..5945
                     /locus_tag="ACGI3L_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFG9198126.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            6084..6623
                     /locus_tag="ACGI3L_002427"
     CDS             6084..6623
                     /locus_tag="ACGI3L_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HFG9198127.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(6799..6969)
                     /locus_tag="ACGI3L_002428"
     CDS             complement(6799..6969)
                     /locus_tag="ACGI3L_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HFG9198128.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            7254..8321
                     /locus_tag="ACGI3L_002429"
     CDS             7254..8321
                     /locus_tag="ACGI3L_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFG9198129.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            8491..10392
                     /gene="cooS"
                     /locus_tag="ACGI3L_002430"
     CDS             8491..10392
                     /gene="cooS"
                     /locus_tag="ACGI3L_002430"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HFG9198130.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            10385..10858
                     /locus_tag="ACGI3L_002431"
     CDS             10385..10858
                     /locus_tag="ACGI3L_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9198131.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            10833..12059
                     /locus_tag="ACGI3L_002432"
     CDS             10833..12059
                     /locus_tag="ACGI3L_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9198132.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRILKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(12198..13385)
                     /locus_tag="ACGI3L_002433"
     CDS             complement(12198..13385)
                     /locus_tag="ACGI3L_002433"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9198133.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRIVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            13658..14482
                     /locus_tag="ACGI3L_002434"
     CDS             13658..14482
                     /locus_tag="ACGI3L_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198134.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GSNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            14611..15876
                     /gene="gluD"
                     /locus_tag="ACGI3L_002435"
     CDS             14611..15876
                     /gene="gluD"
                     /locus_tag="ACGI3L_002435"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HFG9198135.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            16089..16679
                     /locus_tag="ACGI3L_002436"
     CDS             16089..16679
                     /locus_tag="ACGI3L_002436"
                     /inference="COORDINATES: protein motif:HMM:NF017390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9198136.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            17010..18143
                     /locus_tag="ACGI3L_002437"
     CDS             17010..18143
                     /locus_tag="ACGI3L_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9198137.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMREEHKINCEFLGLIPKDSDKIGVGIEYYDSLLND"
     gene            19059..20081
                     /locus_tag="ACGI3L_002438"
     CDS             19059..20081
                     /locus_tag="ACGI3L_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9198138.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            20377..21297
                     /gene="pyrB"
                     /locus_tag="ACGI3L_002439"
     CDS             20377..21297
                     /gene="pyrB"
                     /locus_tag="ACGI3L_002439"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HFG9198139.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            21336..22028
                     /locus_tag="ACGI3L_002440"
     CDS             21336..22028
                     /locus_tag="ACGI3L_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFG9198140.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            22021..22923
                     /locus_tag="ACGI3L_002441"
     CDS             22021..22923
                     /locus_tag="ACGI3L_002441"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFG9198141.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            23008..23592
                     /gene="pyrE"
                     /locus_tag="ACGI3L_002442"
     CDS             23008..23592
                     /gene="pyrE"
                     /locus_tag="ACGI3L_002442"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFG9198142.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            23806..24732
                     /locus_tag="ACGI3L_002443"
     CDS             23806..24732
                     /locus_tag="ACGI3L_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HFG9198143.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(24784..25674)
                     /locus_tag="ACGI3L_002444"
     CDS             complement(24784..25674)
                     /locus_tag="ACGI3L_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9198144.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            25862..26893
                     /locus_tag="ACGI3L_002445"
     CDS             25862..26893
                     /locus_tag="ACGI3L_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFG9198145.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
BASE COUNT        10402 a         3067 c         4443 g         9002 t
ORIGIN      
        1 tatttatctt ttataccagt atctaaactt attatttctt ctgagtattt aactagatta
       61 gattgtattt cctttgaatc aatttgtaat aaatttatta tttctataaa tgtagaaata
      121 tctatatatc tgtgacctaa atcaaatata tctgagataa agctaggtac tttttctgga
      181 actcctggag ttatagctat ttttatattt ttatagttat tatcattcat atatggaatt
      241 ggtctaatat tagtcactcc aattttataa aataaactta tagtttctag agtagtttca
      301 tcagaatcat ttacgattag aacatttgta ccctgtggta aagatagtag attataaatt
      361 ttatcttccc taaaagttct tcttaccaca atcacttttt tcttatctag tatattattt
      421 ataattttgt ctaatctttc tactgacatt actaatatca catcatcatt tataatatca
      481 ttatcattta tttcatttat gaagtatcta ttaatattta tagaatctcc aaaaactaat
      541 ttcaaattat tttctaaaaa gtctattaaa tcttttctac tatcatttac cagagctact
      601 gattttttca tttatttctc cttatataat aaatagtttc caacaaaata gttgtataaa
      661 gcaatataat tttgataatt taaatttatc aaataaaaaa gaaagtgtct ataatgactt
      721 tataaaagtt gcattaagac actttctttc ttataattaa aaatcttgtc accaaatccc
      781 cctaattgtt gcttaaaact taaactgtat gtatattttt catttctatt cgattaaatt
      841 ataatataca cccaaaaaaa tttattttaa taaattctat tgataatata attttgtaaa
      901 tatagaatta tattaaaata aattatatat taaaatatat atgtataagt ttattctgcg
      961 tcagtagaat gaatttgtca agtttaattt agttgtaatt ttatctttta ttaaaaataa
     1021 tataaattaa aacatataaa taaaatattt tatacaatat attgtaaagg aggtaacttt
     1081 gatgaaagca gaaaaaacaa gtatatatcc aattattaaa aataatttaa acaaaatatc
     1141 aattgttgaa tataaaaagg gtcaaagatt tgtagcatca gataaagact tacaagaagt
     1201 gttctttata atagagggag ttgcattagt ggagtgtact actagaggag gaaataaatt
     1261 tcttgttgac attgtacctg aaaatgaatt tataggcaaa attagttaca tatatgaaca
     1321 taatttgaaa tgtgatatat ttgcaaagac caatataaaa ttatttcgat ttgaaaaaaa
     1381 tgtatttgaa gagttttatc tcaaaccaga ttttattgca ctatttcaca gaaaatgtac
     1441 aagaagaata tatgaattat ataaaaccag aatggtaaga gaactatttt cttgcacaga
     1501 agttattgcc tattgtatat caaataaaca agaaaataat gtctgcaata taaaagctat
     1561 tcgtaatttc agtgaaatct attcaattag tagaaaaagt agataccatt ctctgctaaa
     1621 gttaactgaa aaggagatag taaaaaaaat gggtaataca tatgaaattt taaactatga
     1681 tgaattacat aaattggcat ttgaagtaaa agaatttttg gaagatgagt aaaaattgtt
     1741 acttaatcaa aataaagtat aataatttct gtaaaaaata gaaatagtct cactgaaaat
     1801 caaaaatact ttagttattt tcaatgagac tgtttagaaa tattgtatac ttataatgta
     1861 tagtataatt attaatcaat ttcctttact atattaatag cccatttttt agataatgct
     1921 ctaggaacac caaatataaa cttaaccact tcttcactat aagtgagcaa aacgagtaca
     1981 aatataggtg cacctttaaa tgcagctata aaagttagag gaatagaagc taaccacata
     2041 catcctaatt ctaaaaatag agcatattta gtatctcctc cacttcttaa aataccaatt
     2101 ataaccaatg tattaaaaga tttaagagcc attagtattc ccattataaa gaatatctta
     2161 gttatatcag aagctaagct atcagaaaca ctaaacattt ttaataataa tggtatattt
     2221 aaaattaaaa taattccaag tattaaacca gctgaaaata caagtataga aaacttttta
     2281 gcatattcaa tggctctttt aatatggtca gctccaagtt catttccaag cataatagat
     2341 gcaccagatg caatacatac agctgtcatt atgaagaaat tacctgtact ggttgctatc
     2401 tggctagctg ctatagcaga agtaccagct cttgcatatg caacagaata caggacagtt
     2461 ccaattgccc atacagagtc atttacaaat ataggaaagc tttttgatga aaaagatttt
     2521 ataaaaattt tatcaatagc ttttagattt tttagaccaa actttaatat atagtctttt
     2581 ttataaaggt aaacataagt aatcattaaa attaattcac atattctagc aataacagta
     2641 gctagagcag caccttttac acccaatgca ggaagaccga agttaccaaa tataaatcca
     2701 taatttaaaa taacatttgt tacaagtgca aatgcactac aaatcatacc taacttagga
     2761 tttctaacac ctcttgaacc agtgctaaat acagtactta cagcaattaa tggataacta
     2821 aatactgcaa tactaaagta atctatacaa agttttacca cctcagaatc atacgaaaat
     2881 atgtgtataa ttggctttgg tgttagtaaa gcaggaataa caaatacaaa acttaaaaca
     2941 attgccaata cacaagtaag acctgtgact tttcttatat tactcacatc cttctttcca
     3001 taaaactgtg aaataaaaac tccagcacct cctgtgatac cagataagga catattaaaa
     3061 agaaagaaaa attggtttgc aactccaact gaagctacag atgtttcccc caaactactt
     3121 atcataattg tatctattac atttacagaa gtagaaatta agttctgtat gataataggt
     3181 atacataaag atagaagtat tttataaaat cttttatttt cgtcttttaa agaaaatagt
     3241 tcttgcaaat aatcctctcc tttttacata aattcttccc actcatcata tagagaggca
     3301 aggttatttt ctaaattaat tttttcttgg ctaacttctt tagctttatc tggattagag
     3361 tatacttctt cttgacataa aagtatatct aatttttcaa tttcaatctc taacttttca
     3421 atttcttttt ctatattttg tctttttatt ctatttttct tttctatttc tctttgttct
     3481 ctctcttttc ttttttcatc ttttatttga gttctagttt tttcttcttt ttcttctata
     3541 atactcatct cttggatttg ccttttttta tctatataat aatcataatt tcccagatat
     3601 tcagtaattc cattttcatc taaaactaaa attttatcaa caacagtatt tagaaagtat
     3661 ctatcatgtg atattgtaaa tatagtccca tcataattag ttaatgcctc ttcaaggact
     3721 tccttagaat caatatctag gtgattagta ggctcatcta ataacaataa gtttgcattt
     3781 gatagtataa gtttaagtat ggcaactcta gctctttctc caccactcaa tgtagaaatc
     3841 ttcttaaaaa cttcttcatc tacaaataaa aatgccccta acatatttct caaagtagtt
     3901 tgagtaagat gagtattatt ttcccaaatc tcatcaatta ttgtgttatc taaattaaga
     3961 gttttttgtt cctgatggaa gtaggaaaca tgtacattag ttccaaattt aatattgcca
     4021 ctaagaggtt gtagttcatt agttattatt ttaaataatg tagatttgcc aacaccattt
     4081 gcacctataa gtgcaacttt ttcccctcta tatatatcta aatccaagtc tttaaaaagt
     4141 attctttctc cataacccat agatacatct ctaatttgaa gaacatcatt accactctgg
     4201 acagaaggcg taaattgtat acgagctttt ttcctataag cttctggttt atctaaaacg
     4261 tctaccttgt ctaatgcttt ttctttactt cttgcacgct ttaggtgttt ttctctacca
     4321 taagctttta gtctttcaat tgattcttct tgctttttta tttctttttg ttggtcttca
     4381 aatttcttaa gctctagttc tttttctatt ttagataact caacaaattt agagtagtta
     4441 ccattatata ctttaagttt tttgttgtga acttcaaaaa ttctatttac ggattggtct
     4501 aagaaatatc tatcatgaga tattaacatg acagtccctt tatattgttt taaaaatact
     4561 tctaaccatt ctattgcttc agagtctaag tggttagtag gttcatcaag taacaataga
     4621 gttggtttct taagaagtaa ttttcctaaa agaactctag ttttttcacc accagaaagt
     4681 atgcttattg gcttatccat atcattgtca ctaaatccta atccctttag aactcctttg
     4741 gcttcagatt tatatccata tccatttaaa tctgaaaata attctagttt atgtgaatat
     4801 tcatccatga ttttttctat aattggagag tttgtttttg tactttcttc agatatttta
     4861 acctccaatt ctcttaaata ggattccatt tctatcaaat ttttaaaaac ttctagtact
     4921 tcttccaaaa tagtattatc cgaataaaaa ttggtatttt gttctaaata tccgatttca
     4981 caatctttag aagtgtaaat atctccacta tcatatccat aaattcctga aattatttta
     5041 aataaagtag tttttccagt accattaaca ccgattatac caattttatc gccttcattt
     5101 actgtaaaac taatattttc taatatagaa tctataccaa aacttttatt taagttatta
     5161 catgacaaaa caatcataaa tttctacctc cttgaactat ctaaaattat aatgttttga
     5221 tataatataa tcaaggttat atgtattagt tttgaaaaag aaatatttta ttgtgaatca
     5281 aacaaaaaag aggacacttt taggaggtga agatgttggg aaataaaaat atatcaatgg
     5341 cagttataag aaggctccca aaatatcata gatatcttgg agacttatta gatagggata
     5401 tacaaagaat atcttctaaa gaattgagtg atataatagg gtttaccgct tctcaaataa
     5461 gacaagattt aaacaacttt ggtggatttg gacaacaagg atatggttat aatgtagaag
     5521 ctcttcatac tgagataggt aaaattcttg ggttggatcg accatacaac gcagttcttg
     5581 taggagcagg taacttagga caagctatag ccaattatgc aggatttaga aaagctggat
     5641 tcgagataaa agctttattt gatgcaaatc ctagaatgat aggtttaaag ataagagagt
     5701 ttgaagtatt agattcagat actttagaag actttataaa aaacaataat atagatattg
     5761 ctgtattatg tatacctaaa aatggagcac aagaagttat taatagagtt gtaaaagctg
     5821 gaatcaaagg tgtatggaat tttgcacctt tagatttaga agttccgaaa ggtgttatag
     5881 ttgaaaatgt aaacttaaca gaaagtttat ttaccttatc gtatttaatg aaagaaggaa
     5941 agtagacaac ttaaacatat taataatgag cagttgtgaa gagtattgag aaagtcagaa
     6001 gatttaatat taaatcctct ggctttttga aatattagga taaaaattta aataatgtat
     6061 ggaaataaac aatattaagg agagtggttt ttgtggagga attatggaaa aaggcaattg
     6121 aatttcatgg tcatgaatgt ccagggttag ctataggatt taaagcagca cttgcagcaa
     6181 gagaatattt aggatgtaaa cagtcaggag atgaggaaat tgtatgtatt tctgaaaatg
     6241 atgcttgtgg aatagatggt atacaagtcg tgctaagttg cacaatgggt aaaggaaatt
     6301 tactacttag gatgactggg aaatcagtat atcatttctt taatagggaa aatggaaaat
     6361 ctataagaat atatgtaaag tcaaagccat ttcaaatgga tagagaagga tacaaaaagt
     6421 acttattaga aagtgatttt gaagaaatat ttgagattac agatactaag ttaagacttc
     6481 ctgaaaaagc aagaatattt aaatctctta aatgtgaagt gtgtggtgaa tttgcatctg
     6541 agcaatatat aaggattgaa gaaggaaaga aagtatgtct tgattgcttt aataaatatg
     6601 aaagatttta tgaggagtat taaaattata aattagatta aagttaaaag tattagatat
     6661 gtgctaacag tattttaaga tgaattaggt agcaacataa taaagtatat aaataatatt
     6721 aattgaatca tacataatta aaaagaggct gattagtatt tataaaataa aatcagtctc
     6781 tttatgaata acgaattatt attctggttg aggtgcatct acaggacaag ctcctgcaca
     6841 agaaccacag tctatacaag aaccagcatc tataacatat gcgtcgtctc cagctgatat
     6901 acagctaaca gggcattcag cctcacaagc accacagctt atacaagcgt cagtaatttt
     6961 atatgccatt ttgaaatcct cccttttata tgtattgtaa ttcaataaca ttataacaaa
     7021 tattattgaa tataacaatt aaattaattc tacaacaaaa actttattat gatattcttg
     7081 ttttaaagtt ttacaataaa gtttaatctg cttatatttt tatttatttt aaagaagttt
     7141 attttaaaaa taaaattaaa tttaaaaagt tatgtattga ttatatttaa aaatgttata
     7201 ctctaaaaaa gtatatttta tttaaaaatt tattaataca aaggagattt actatgaaaa
     7261 ataaattagt ttacatatgt attatgagtc tattgctatt tgtagtagga tgttctaata
     7321 atccaaataa ggaaagtacc attaaaaaag actctaagaa taaccaaagc caagttaaag
     7381 aagaaaaaag agaacctgtg aaaaaagata taactataag tttcgctggt gatgtaacta
     7441 tggggaacta taaaggttca tcatattatg gcagttttga ccatgaattt aaaagacaag
     7501 gagaagatta caattatttt cttaaaaatg taaaacctgt atttgaaaaa gatgacttaa
     7561 cagtggttaa tttagaaggt ccacttacta cagcgtcaaa tgcaaaagaa aaaaaatttg
     7621 catttaaagg aaagcctgga tatgtaaata ttttaaaatc tggaagtgta gaggcagtaa
     7681 gtattgcaaa taatcattca gaagattatt ttgaagaagg aatgaaagat acacagttta
     7741 tattggacga gaataaaata aattattttg gattagggaa agatgctgtt gtagatgtca
     7801 aaggaattaa agtgggtcta ttagggtata atggattatc aactgaatat aatgaaaaaa
     7861 atttaaaaca aatggaagat gatattaagt ccttaaaaaa gaaatcggat gttgttgtag
     7921 tgtactttca ttgggggata gaattagatt attatccaga taaaaaacaa aaagattttg
     7981 ctcattatgc tatagacaag ggagcagatt tagttatggg gtctcaccca catgtgattc
     8041 aaggaataga aaagtataaa aataagtata tagcttatag tctagggaat ttttgctttg
     8101 gaggaaataa gaatccttct gatacagata gttatatata tcaacaaacc tttacttttt
     8161 cagataataa attaacttca attaaagagc caaatataat accaacttca ataacatcta
     8221 gtaactccag aaataattat caaccaaaaa tattggatgg aagtgagaag gatagagttt
     8281 taaataaact tgaaaaaata agcaaagatt taaataaata aaatgtaaaa aaaaataaat
     8341 atatatattt attttaataa tttatatttt gtttagggta tggtaaatcg tggtattaaa
     8401 taagtagatt ttaatagtta aattatagtc aattataata aagctattta atctactttt
     8461 ttaatataaa aatataaggg ggaatttgta atggcttgta acacttgtaa aatgtgcgaa
     8521 agtgcagaca agaaattaga aagttttgta gcttcaaagg atgttgaaac agcatttcat
     8581 agaacagaag atcagaaagt taagtgtggt tttggacttc agggggtttg ttgtagactc
     8641 tgttcaaatg gaccatgtag agtaactcct aaatcaccaa gaggtatatg tggagcagat
     8701 gcagacacta tagtagcaag aaacttttta agagcagtag catcaggagc agcttgttat
     8761 ttacatgtgg tagaaaatac agctaagaat ttaaaaaatg ttggaataac taaaggtgtt
     8821 gttaaaggag aaaaaacatt aaatcaatta gcagagatgt ttggaataga aagtgatgaa
     8881 aagtatgata aatgtataaa ggttgcagac aaagttatca acgatttgta taaatcaaga
     8941 gatgataaaa tggaattagt agaaaaaata gcttatgcac ctagagtgaa aaagtggaaa
     9001 gagttaggta taatgcctgg tggtgcaaag tcagaagttt ttgatgcaat agtaaaatca
     9061 tcaacaaatt taaatagtga cccagtagac atgctagtta attgtttgaa cttaggtata
     9121 tcaacaggat tatatggtct tacactaact aatcttttaa atgatgttat gttgggagaa
     9181 ccagttataa gaatggctcc tgtaggattt aatgtaatag acccagacta cataaatata
     9241 atgataacag gccatcaaca ttcaacattt gcaaatttcc aagatagatt aaaagatgaa
     9301 gatgttataa aattagctca atctgttggt gcaaaaggct ttaagctagt aggatgtaca
     9361 tgtgttggtc aagatttaca attaagagga gaacattatc aagaagtatt tgctggacat
     9421 gcaggtaaca attttacaag tgaggctgtt ttatcaactg gagcaataga tatagttctt
     9481 tcagaattta actgtactat accagggctt gaaccaatag cagataaata taaagtaaaa
     9541 atggtttgtt tagatgatgt tgctaaaaaa gcgaatgcag aatacatagg tttagacaga
     9601 agtaaattag atgaacttag taacacttta atagaaaaag cattggagtc ttataaggag
     9661 agaagaggaa gtattgaaat agatatacca aaagaccatg gatttgaaca atctttaact
     9721 ggtgtaagtg aaaagaacct gaaagcgttt ttaggagatt catggaaacc tcttattaat
     9781 ttaattgcag aaggaaaaat taaaggtgtt gcagctgttg taggatgttc aaatatgaca
     9841 gcaggaggac atgatgtaaa tactgttgaa cttactaaag aattgattaa aaaagatata
     9901 atagtactat ctgcaggatg ttctactgga ggattagaaa atgttggtct tatgtcacct
     9961 ggagcagaag aattagcagg agaaaactta aaagaagtat gtaagacttt aggaatacca
    10021 ccagtattaa actttggacc atgtctagct ataggaagac tagaaatagt agcaacagaa
    10081 ttagcagctg aacttggaat tgacctacca caattaccat tagtgctttc agctccacaa
    10141 tggttggaag aacaagcatt agctgatgga gcgtttggtc ttgcccttgg cttacctctt
    10201 catttagctt tacctccatt tataacagga ggaaaattgg tgacagaagt attaacagaa
    10261 aaattaaaag acttaacagg aggacatgtt atagtgaatc cagaccctaa atcttcagct
    10321 aatcaattag aagaaataat aatagataga agaaaaaatt tagggttaaa ggatgtggaa
    10381 tgcaatgcat agaattttta taaataaaga tttatgtaca ggatgtaaga gctgtgtact
    10441 agcatgtatg ctaaaacaca ataaagatta tgacatgtac actcttgatt tagaaaatat
    10501 agataatgat agtagagggc atatagaatt agatagtaaa cataataatc cagttccaat
    10561 tctttgtaga cactgtgatg aacctgaatg tgtattagca tgtatgagtg gtgcaatgca
    10621 taaagatagt gaaagtggaa tcgtttcata tgatgaagag aaatgtggtt catgttatat
    10681 gtgtgtaatg tcttgtccat atggattatt aaagccagat gatagaagca agcagaacat
    10741 acttaaatgt gatttatgta aagatgagga gtatcctaga tgtgtagcta attgcccaag
    10801 tggagcaatt gaattacaga aggaggaaaa tgatgaatta tgtagtgtta ggggctagtg
    10861 cagctggtat aaatgcagta aaaacattaa gagaattaga taaagattca aatatagtag
    10921 taatttctaa agatgaaaac gtatattcaa gatgtatgtt gcatcacgtt atatctgaac
    10981 acagaatttt aaaacaaata aattttgttg atgaagattt tatggagcaa aataatgtaa
    11041 aatggattgc aggtaagact gttaaaggta tagacataaa taaaaaggta gttcagacag
    11101 aagacattac tgtaaattat gataaacttt taatagctac aggtgcatct tctgctattc
    11161 ctcctataaa aaatttaaga gatggaaatt ttgtatattc tgtgagaaac atagatgata
    11221 tttataaaat aaaagaaaaa gcacaaaatt ctaaaaatgt agttataata ggtgctggtt
    11281 tagttggtat agatgcatta gtgggattat ttaaatatga gcagttaaat atttctgtag
    11341 cttttatgga aaagtacatt ttagatagac aattggatga atatacagca tcagtgtatg
    11401 aaaataagtt caaagaaaaa ggtgtaaaat tttacccaag tgcatcaata caagaaattg
    11461 tattggataa cagtaaaaat gttacaggtg ttgcattttc aaatggtgaa gttttagatg
    11521 cagacatggt aattgttgct acaggggtta aaccaaatgc tgacttttta gatggaacag
    11581 gaatagaata tgatagaggt ataataatag atgatatgtg ccaaacaaca caaaaagaca
    11641 tatatgcagc aggagatgtt gtaggtaaaa atgctatttg gcctctggca gtaaagcaag
    11701 gaattgtagc tgcctataat atggttggaa aagataagaa gatagaagat gaatttgctt
    11761 ttaaaaacag tatgaatttc atggatatac caactatttc tataggaatg aatacacctg
    11821 tagatgatag ctataaagtg ctaactagac atggaattaa tgattataaa aagtttgttt
    11881 ttaaagataa tgtaatctat ggagcagtta tacaaggaga tatttcatat gtaggtgtat
    11941 taacttattt aataaaaaat aaagttgaaa tatatgattt agaaaatagg atatttgata
    12001 tatgttatgc agactttttt aatataaaag aaaatggaga attttgttat agtgtatagt
    12061 atatacgtgg agtaaggttt ataaatacag taaatcaata aatagagtta ttctaaaata
    12121 agaaaaatga caaatcttat ttagaaatag ctctattttt tgtaattaaa tttaaattat
    12181 attcaatttg taaaatatta ttttgaacaa ttatacatat actctctagt tagaggtaaa
    12241 tcatttttta tacctttagt gaaaagtatt tgatgtatat ctataatacc agtgttgaaa
    12301 gcagcagcac aagaacaaag gtataaatcc cacattctta taaacttatc atcaaacatt
    12361 tctttaatct ttggaagatt ctcagagaaa tttttttgcc agtatagtaa ggtttttaca
    12421 taatgtaatc ttagactttc tacgtctata gtatgatatt tgtaatcact acaaatatgt
    12481 atcatttctc ttaggctagg aataactcct cctgggaaaa tatatttttt tatccaaggg
    12541 tctccataag attcctgcaa tccacttata tagtgaagta aaaacaatcc accatctttt
    12601 aaaacagcat ttacgttttt aatgaaaagt tcatagtttt ctctaccaac atgttcaagc
    12661 atcccaacgc ttacaattct atcaaacata aggtctgatt tttttaattc tctatagtcc
    12721 ataagtctta cttcaagata gtcttgaagg ttctcttctt taattcttgc gttaaattcc
    12781 ttaaattgct cttcgctaag tgtaattcca acgccgtgaa ttttatattt ttttgcagct
    12841 tctattagta aaaatcccca accacaacca atatcgagaa ggctcatacc ttcctctaaa
    12901 tttagtttag ttaatatgtg gtgaacttta ttgacttgag catcataaag agtatcatta
    12961 tcatttctaa agtatgcaca agaataacta agtgtcttat ctaaccataa gctataaaaa
    13021 tcgttgccaa tgtcatagtg ggcatgtatt tctttctttt gatgtctcat tgaatttgat
    13081 gagtgcaata gatgttttac agctgaatta tcaatattga atttgtctat ttgttttaaa
    13141 agtagattta aagttaagaa taaatctccc tcaacttcaa tgtctctatt tatgtaggct
    13201 tctccaagtg ctaaagatgt actttttaat agttcagact tgctaatatc attatttact
    13261 ataactttga actgagggga gccctctcca attagaaatt cttcctcatc tttaagccta
    13321 actagaaatg gtgtttcacc aaatttctct aaatagtctt ttaaaaaatt ttttgtaata
    13381 ttcatattac cagctccttc taatgtaaat ccagtaagtt tccctgctta aaatatatta
    13441 tagtcctttt tttaaaaaag taaaattttt tcaataaatt ttttatttaa aggaaattta
    13501 ttttttataa agaaatttca tgttgtagta tattttttgc ttataaattt tggtactgga
    13561 tataatatta aactgttaat gatataataa atttaatcta taaagtaaat aaaattttgt
    13621 aataaatagt taaagctatt ttataaggag atatatgatg gaagtatatg ctttggttgg
    13681 gtcaagtggc acagggaaga gctttaaggc tttagagttc gcatatgaaa atgatataga
    13741 atatataatt gatgatggga ttttaatata caaaaacaag gttttagctg ggatatcggc
    13801 aaaacaagca aatactacta tagaagcagt taaaagggct attttttata atctggagca
    13861 tagacaagaa gttagagaag caattaaaaa agaaaatata agaaaaattc ttattattgg
    13921 gacatcaaaa aaaatggtta atcaaattgt agagagattg tcaattggaa gggtttgcaa
    13981 gtttataaat atacaagata taagtactaa atatgaaata gaaatagcaa aacaagctag
    14041 aaaagaagga aatcatgtaa ttcctgttcc agcagttgag ataaaaagta tggcaagtgg
    14101 tcttagtata aattctttga agagactttt tagaaaagga agtaatagga atatggtagt
    14161 tttagaaaaa acaattataa gaccaacttt tagttatata ggaaagtttt atattagtgc
    14221 tgatgtaatt aaacagatta ttgaatatga agtatacaac tttggaagca ttgatagaat
    14281 aaataaaatc aatatagaga attgcaataa ttttatgaat atttttgtaa gtataaatat
    14341 caatgattta gaaactataa aaaaaattga agacatacaa cagacaataa aaaagtctat
    14401 tgagaaaatg actttagtta atgtacaaaa aatagatatt aacattcata aaattaaaaa
    14461 aataaacttc ctccaatgtt aaaaaataaa ctgagaaaat gatatactaa tttgcaataa
    14521 agtgtgctat aattaaactg taaatttagg aaatggtttt ttctaaatgg agtatacata
    14581 attataacgt atttataagg gggctttcaa atgtcaggaa aagatgtaaa tgtcttcgag
    14641 atggcgcaat ctcaagtaaa aaatgcatgt gataaattag gtatggaacc agcagtttat
    14701 gaattattaa aagaacctat gagagttata gaggtttcaa ttccagtaaa aatggatgat
    14761 ggttctataa aaacttttaa aggatttaga tcacaacata atgatgcagt agggccaaca
    14821 aaaggtggaa taagattcca tcaaaatgtt tcaagagacg aagtaaaagc tttatctata
    14881 tggatgactt tcaagtgttc tgtaacaggt ataccatatg gtggaggtaa aggtggaata
    14941 atagtagatc catcaacttt atctcaaggt gaattagaaa gattaagtag aggatacata
    15001 gatggaatat ataaattaat aggtgagaaa gttgacgttc ctgcaccaga tgtaaatact
    15061 aatggtcaaa taatgtcttg gatggttgat gagtacaata aattaactgg acaaagttct
    15121 ataggtgtta taactggtaa gccagttgaa tttggtggtt ctttaggaag aacagctgct
    15181 actggatttg gtgttgctgt tactgcaaga gaagctgctg ctaaattagg aatagatatg
    15241 aaaaaagcta aaatagctgt tcaaggtata ggaaacgttg gttcttatac agttcttaac
    15301 tgtgaaaaac ttggtggtac tgttgtagct atggctgaat ggtgtaaatc agaaggttct
    15361 tatgctatat acaatgaaaa tggtttagat ggtcaagcta tgttagatta tatgaaagaa
    15421 catggtaact tattaaactt cccaggagct aagagaatat ctttagaaga gttctgggct
    15481 tcagatgttg atatagtaat accagctgca ttagaaaact ctataactaa agaagttgct
    15541 gaatctataa aagctaaatt agtttgtgag gctgctaatg gaccaactac tccagaggct
    15601 gatgaagtat ttgctgaaag aggaatagtt cttactccag atatattaac taatgctggt
    15661 ggagttacag tttcttactt cgagtgggta caaaacttat atggatacta ctggtcagaa
    15721 gaagaagtag agcaaaaaga agaaatagct atggttaaag catttgaatc tatttggaaa
    15781 atcaaagaag agtacaatgt tacaatgaga gaagctgctt acatgcattc aattaagaaa
    15841 gttgctgaag ctatgaaatt aagaggatgg tactaagatt tactcttaat aaataatagg
    15901 atataattat ttaagatata aaggggctgt acatagtaca gcccttaaat tatgtggctt
    15961 acaatgaagt aagctatttt tgttttaact tataaaaaac ttgataaatt atgtaattta
    16021 gaatgtattt tttaccacca catgattaca aattagaaga gttagattag atttttagac
    16081 atgaacttat gcattttaaa agcaaagacc ttaatttaaa gtatctagta ttatttttaa
    16141 aaatagtata ttggtttaat ccatttatat atataatgga aaaatatatg gatttggatt
    16201 gtgaacttta ttgtgatgag agagttttaa aaaattgtac tgtacaacaa aagcaagaat
    16261 atgctctaac tattgtaaat tcaatgaaaa gaagtacaaa tttttcaaat aaatttgtag
    16321 ctggattaaa taaacaatct gatattagaa aaagagtaat aaacatgttc agtgaaaaac
    16381 ataaaaatgg tatcttaagg gctttgatta taagcttgtt ttcttctatt acatttttta
    16441 aattcgattc aactagtatt attgaagaga atgatttctt agagaggtca agatatacgt
    16501 ttgaaggaag gcaagaagac atgtttgtaa caatagattt tatatatgca gatgtaccta
    16561 taaaacttag aaaagagcat gaagaaaact gtagagtcaa tggaatagta ccaaaagatt
    16621 cagattcaat agaaattatt cctagatttt ataaagattg tatggattta aaaaaataag
    16681 ttagacttaa tattgatgtt gatattatga attttttata tttaagcaat tgaaaatttt
    16741 attatagatt caattttata tgtgtttaag tatgaaattt atagatagtt gaaataatta
    16801 aatatgattg atgcatagga atcattacta agctataatt aattataagg gagtttaaat
    16861 aaattatgag ttacacaatt ataaaatgat aaaaaatagt tatctgttac aaaaaatgta
    16921 tctttttaat taataaagat aatatgaaaa cttaaaaggc aaataaactt aaacataaaa
    16981 tactcttaaa taagatagga gaaaaatgta tgtctaactt tattctaaat gggattttta
    17041 gaacagttat agtaagtagt ctaagcattc ttatgatatt gattttcaag aaaaatgtat
    17101 ttaaaagatt tagcaaaaaa tttaattatt atatatggat gatagttgtt attaaattat
    17161 ttttaccatt tacatattat acttttacaa taaatatctt gagaagtaaa aaacacatta
    17221 atattaataa cataaattta gagggattta ataatgtttc aactataagt aataatatta
    17281 tattgtacac ttggattata actgtagtag tttatttaat ttacactata tttaaatata
    17341 taaaacttaa aaatttaata aatgacttat cttatgatgt tgatgatgga gagattgtaa
    17401 atctttataa aaatatatta gaagaattta atataacaaa agatataaaa ctcaaatact
    17461 cttatgaagt tgaaacacca gcatttttta attcatgtgt gcttttgcca ccacatgagt
    17521 ataaattgaa agagttagac tggattttta gacatgagct tatgcatttt aagagtaggg
    17581 acctttattt aaaatatgta atcctgtttt taaaaacagt atattggttt aatccattta
    17641 tatatataat ggataaacat atagatttag attgtgaact ttattgtgat gaaagagttt
    17701 taaaaaatcg aaattcagag gaaaaaaagg attatgcttt aacaattcta aatgcaatga
    17761 gaaaaggttc aaatacttca aataaattta tagctggact ccataagcaa tctgatatta
    17821 aaaagagagt tatgaatatg tttaatgaaa agtacaagaa tggtatatta atggcattaa
    17881 ctttatgttt attatcttct attacttttt tgaaggttaa ttcaacgagt attgttaatc
    17941 ttaatatatt gccaaaagga atggaagaaa aagatgttac taatagtgca attgttacaa
    18001 tgatagaatt tacatatgca gaagctccta aaagtatgag agaagaacat aaaataaatt
    18061 gtgaattctt aggtttaata cctaaagact ctgataaaat aggtgttggt atagaatatt
    18121 atgacagtct attgaatgat taaataaata ttattttaac agatattaat tataaagttt
    18181 tgaatagtaa tttgttgaga aataaatata tccttataaa aatagatact tatataccaa
    18241 gaataaaaaa tagtcaagat agtacacaag gatatactta taaagaactc aaataagtga
    18301 aataaattat taattataag gtttataatt ttaaaaaatt agataaattc aggtgtaaaa
    18361 tactataaaa cacaattcgg aaaagtgtat gttgaacttc atttaaaatg gaatttcaaa
    18421 gttgctatag taagtagttt aagcattctt cttatattaa tctttgagaa taatgtattt
    18481 aaaaaagtta gtaaaaaatt taactattgt atattaatga tagttgctat tgatatatta
    18541 tctaaaaaaa ttaagtatga aaagattact gctaggacaa tcttttcata cttaattttt
    18601 aatatttata ttatccaaaa ttttcatctt tttaacttag aatttgagaa tcactattag
    18661 gaaataggct ttgatttatg tagggttaaa aatttcacag aatatctaac tttatactaa
    18721 atccatcaaa aaatatacgc catataaaag cgcataaaaa aacacataaa acaatattta
    18781 tgcgcacttt aacctcgaat ggtacaaaat tctttacttt tacagaccca tattatataa
    18841 ttaagtaaat aatgtatatt taggtgacat attggataag ctaatttatt tattttatta
    18901 atataatgat actataaaag ttatataaag tggtttacaa aaaagttaca gatagagctt
    18961 ttattaatgt attgtgtatt agtattttat ccttaggtac acttcaccta caaaatagaa
    19021 tcataagata attatgggaa aattttagga ggtttatcgt gaagaaaaag atattaatac
    19081 cagtatttgc atcagttatg gcattatcag taagttcaat tgtaaatgca gatgaagtaa
    19141 atgattcatc tcaaaataag gatgataaaa caaatactga attaaattta ggtgaatata
    19201 aagaagtaaa atataaagtt gcaaaaataa aagatggagt agctataaag ataagagaag
    19261 aaggtcaagt tcaaaacata gcttattctg gagatgaatt tacggtttta ggaactcaag
    19321 gagaatgggt taaggttaaa gttgaagatg gcgaaggttg gttagctact agatatgtag
    19381 atatatctga aggtgtagga tatactaacg ctgataaagt aaacttaaga aaagataaga
    19441 gtgaaagttc agaagtaatt gaagagctgg aaaaaggaag ttctttattg gttttggaag
    19501 ataatggaga ttggttaaaa gttaaagatg gggaaacaga aggatatgta aaatcatctt
    19561 atatatctga taaagctcct gtaatagaag agccacaagt aaacccaagt attgaccaaa
    19621 atgtagattc tacaaataat aatcaacaaa acaatgcaaa tactaatcaa caaaataata
    19681 attcaaatgt gccaacagct aactctaatg cagttcaagc tgtacttaac ttggcatatt
    19741 ctaagcaagg ttgtccatat gtttggggag cagaaggacc aaacactttt gactgttctg
    19801 gatttacaca atatgtgtat agaaatgcag taggaaagaa tataccaaga acatctaaag
    19861 cacaatctaa atatggacaa actgtaagta aagcaaattt acaaccagga gacttagtat
    19921 tcttcacaac taatggttct ggttctgtta gtcatgttgg aatatatgta ggtgggggta
    19981 atatgataca ttcaccatca acaggaaaaa cagttagtgt aactagtata aattcatcat
    20041 actatacagc aagatttgtt acagcaaaaa gaatattata atcggtttgt aatatgacaa
    20101 attgataaat acataaatat atataaacgc tctatattat atttaattta atcatggaaa
    20161 caaaaaatga ttatatttta aatgtactat agagcgtttt tgtatcactt taaatctaat
    20221 caagattcaa gttaatatga ctgttaaata ggagcctttt catatgatga ttatttgcgc
    20281 aatcccttga caggataggg caaaggtggt aagctactaa cagtacaaaa atacttttaa
    20341 ttttagttca gagaggctaa aaaaggagga cgaaagatgt taaaatcaag aaatttaatc
    20401 cagccagaag acttttcaat agaagaaata gatgaaatat tagaattagc tcaaaaaata
    20461 attgacaatc cgtcaaaata ttctcgtata tgtgaaggaa aactattagc tacattattt
    20521 tatgaaccat caacaagaac aagattaagc tttgaatctg ctatgaacag attaggagga
    20581 cgtgtagtag gcttttcaga gccaaattca tcctctgcat caaaaggtga aactctagga
    20641 gatacaatga ggatagtatc tggttatgtt gatataatag ctatgagaca tcctcaatca
    20701 ggtgcagctt cagaagcagc tagatatacg gaagtgccat ttataaatgc aggagacggc
    20761 aaaaaccagc atccaactca aacacttaca gacttactta ctataaaatc attaaaagga
    20821 actttagaaa gccatacaat aggattatgt ggtgatttaa aatatggaag aactgtgcat
    20881 tctttggtta aggctatggc aagatataaa aatacaaagt ttgtatttat agcgcctgaa
    20941 gagttaaaaa tgccagatta tataaaagaa gctataaagg gacatgcata ttatgaaact
    21001 aataatttgg atgatgttat aggaagcttg gatgttttat atatgactag agttcaacaa
    21061 gaaagatttg aagataaatc agagtatgaa agacttaaaa actattatat tttaaataaa
    21121 gctaaattag aaaaggcatc taaagatatg ttagtaatgc atccattacc aagagtaaat
    21181 gaaatagaca tagatgtaga tagtgatgat agagctgtat attttaaaca agctaaatat
    21241 ggaatgtatg ttagaatggc tttaataata aaacttttag gtataaatga agactaatag
    21301 ttatcatata atagtaaaac aaaggagatt ttgggatgta taaaattctg gaaaatatat
    21361 atataggcga agatatgtat agaatgaaag taaaaggtaa ttttgaaggt aaaatgggac
    21421 aattctatat gttaagagca tgggatactt atccagtact ttcaagacct ataagtatac
    21481 atgatataga tgaagaaggg ataacttttc tttataaagt agtaggagaa ggaactcaaa
    21541 ttttgagtaa cctaaaggta aatgataata taaaattaga aggcccttat ggtaatggat
    21601 atgctaaggt tgatggaaag gtagctctag taggaggagg aatcggtgta gctccactat
    21661 atttggttgc taaaaatata aaaaattgtg atgcatatct tgggtttaga gaagatgtta
    21721 tattagaaga tgaatataaa caagtatgta ataaagtcta tacaacagta ggaaatactt
    21781 ttgtaacaga tataattgat gttgagaaat atgattatat attaacatgt ggtccaactc
    21841 caatgatgga aaaattagtt aagatggtag aaggtactaa aacgagaatt atggtatctc
    21901 ttgaaaacca tatggcttgt ggagtaggtg cctgtttagt atgtacgtgt aaaactaatg
    21961 gaggaaataa aaagacttgt aaagatggtc cagtgttctg gggagaggac gtgattttta
    22021 atgggtaatt taagtgtgaa atttggaagt gtagaattta aaaatccagt aataatggcg
    22081 tctggaactt ttggatttgg aaaagaatat aatgagattt atgatataca aaaacttggt
    22141 ggtataagta gcaagggtct tactttaaat aaaaaacctg gtaacaatgg tatgagagtt
    22201 catgagacat catccggtat gatgaatagt gttgggcttg aaaaccctgg agttcaagga
    22261 tttatagact atgaattacc tttttttagt aaactagact tagtcagaat agctaatgtt
    22321 ggaggtggga cattagaaga ctacttatta ggggttcaaa tgttaaatga caagcctata
    22381 gacattattg aattaaatat atcttgccca aatgtcaaag ctggtggaat ggcttttggt
    22441 ataaaaaatg aagtggcaag agaagttgtt cgtgaggtaa gaaacataac gaaactgcct
    22501 ttagtaataa aattatcacc caatgcagaa gatattgtag gaatggcaaa agtttgtgaa
    22561 gaagaaggtg ctgatggagt ttcattagtt aatactttta aagcaatggc aattgatata
    22621 aaaaatagaa gaccagtatt tgaaaatgta tatgctgggt tatctggacc agctataaaa
    22681 cctatagctt tgagaatggt acatgaagtg tgtaaaaatg taaatatacc tgtaatggga
    22741 atgggcggaa taactaaagc cacagatgct atagagttta taatggcagg agctacttgt
    22801 atccaagttg gaactgcaaa ttttatgaat cctagaatag gtattgaaat aatagatgga
    22861 attaatgaat ttatggatag agaaggaata aaaagtttag acgaaataag aggaattata
    22921 taaggtagaa taaatagtat tttaaagata aaaaatatag attaaataaa caataatttt
    22981 ataacattaa catggaggaa aaataatatg agtaaagtag atgtagtgga tatattaaag
    23041 aaaagtgatg cattgttgga gggacatttt ttattatctt caggaaaaca cagtaataga
    23101 tacgtacaat gtgcaaaagt attaagattt ccagaatatg ctgctgaggt attaagtaca
    23161 gttgttgaac aaataaaaga cttagatata gacttagtag taggaccagc tatgggtgga
    23221 gtaatagttt cttatgagtt aggaagacaa ttaggaaaag aagctgtatt tactgagaga
    23281 aaagacaata caatggagtt aagaagagga tttgaagtta aaaaaggagc aaagataata
    23341 attgctgaag acgttgtaac tactggtaaa tcaactatgg agacaaaaag agtattagaa
    23401 gccttaggtg gagaagttgt aggtgttgca tgtatagcag atagaactaa tcatgatata
    23461 ggtatgccta tatatagtgc tataaaactt gatattcaag tttatgaatc tgatgagtgt
    23521 cctttatgta aggaaggaaa attaccagtt gttaagcctg gaagtagaga gttcaaggaa
    23581 ttagggatgt aataaaaact taattattta tagtgttact taaaaaatgt aaatttttta
    23641 gagtaaaaat ttgtaatata acatataact taaaaataaa aagcagttag ccttataaat
    23701 gaaggttagc tgtttttttg ttaaaaatat atttacaaaa taagagatag tagcagtaca
    23761 atataagtat aaggtaaaag tattatatat tagggagggg taagtatgaa aaatcaatta
    23821 aatgaaaatc ataaaaaggt tgtatttttt ggagtaggtg ctgtaggagc tacttttgca
    23881 gaacaatttt ttaactctaa atatgatttt aaaattcttt gtgataatga aagaaagaaa
    23941 agatatttag aagaaggatt tataataaat ggaaaaaggt atgattttga ttatgtaact
    24001 aaagatgagt ataaacaaga ggctgatttt ataattatag gtctaaaata taataattta
    24061 aaagaaaata taaaagaatt agatggatta gttggaaaaa atacagttat aatgtctctg
    24121 ctaaatggag ttgatagcga agagataata ggagaaagat ttggaattga aaaaatggta
    24181 tattcatatg ttaccaatat agatgcaaag aaaatcaata ataatattat acacactact
    24241 aatgggataa ttgtatttgg taacaaagat aatagtgaag atagaaaaac taatataata
    24301 accgaagtct ttgatgatgt aaatatagaa tatactttat caaaagatat tcaacgagat
    24361 atgtggtgga agtacatggt taatattggt gtaaatcaaa cttcagctat acttggtgca
    24421 ccttatggag tttttcagag ttctgagcat ttaagagaat tagcaaaatc tgcaatgagg
    24481 gaagttgttg ctatagcaca agcaaaagac atatctctta cagaagatga tgtggaacat
    24541 tcattacata gaatactaga acattcaaaa gaaggaagaa catcaatgct tcaagatgtg
    24601 gaagctcata gacttacaga agtagatatg ttttctaaga atatctgcaa acttggaaaa
    24661 aaatataaca tacctactcc tataaatcag actttctttt atatgataaa agtaattgaa
    24721 agtagatttt aaagggtctt tgtaagaaat attgataatt attgatttta aattttatta
    24781 atgttatata ctatttaagt tactaaatat ttttaactct tcaatgaaaa tagttgctgc
    24841 ttttgataaa gttatatctt ttggaaatat atatgagaaa tgtctgttgt agctgcttcc
    24901 aagctctatg acagacagct cattgtttag aacaggtaag cttgtcacta gattagagac
    24961 tattgtaatt cctaaattat ttctaacaga ttctttgaca gcataattac ttccaaaaac
    25021 catcatactt tttggaataa tttctttaac acttaaaaac atatctaaat aatctctggt
    25081 tccagaacca tcctccctga ctatccattt ttggttttga agtttatcaa aactaaaatc
    25141 ttttaataaa tgactcttgt atggaagtgc taaaaccatc ttatcttcaa aaaaatattc
    25201 ttgaataaat gaaggggaag agcaagtgcc ttcaataaga ccaatgtcta aaatataatc
    25261 cttaacatga gaagatacga ttgatgtatt ttttataaaa acttctacat ctatgtcagg
    25321 atacttttta gaaaataatg ctagaaaatt tggtaaaata tactctccaa tagttaaact
    25381 tgcaccaatc tttaagtgac cagttatagc atctgaaact tggcttacat catgataagt
    25441 aatatttaaa agatttaata tttctttagc tcttttgtac aagatttgtc cactttctgt
    25501 tataaaaatg gttttttgtt taatagacct gtttataagc acaactttaa aataattttc
    25561 tagatttttt atgtgtttac ttacacttgg ttgtgataga tttaaatatt ccccagcttt
    25621 agtaaagttt ttgtattcaa caacagctac aaatgttttt aattcttcaa acaatttttt
    25681 gtctccttta cctaatgaaa ttttacattt tttatatact ttctacagat aattatacta
    25741 tatataataa ccattaaaaa cattaatcat tacgatatta tatatttatt ttacttatgg
    25801 ttattacaat tatatactat tgctatgaag aaaactatat taattataag gtaggtatat
    25861 tatgttaaag aaaaaaagca gtttgacatt aaaaactata agggaaatat taccaggact
    25921 gtttgtatca gtattagtag gttatattag tatatttatt tctattttaa ttcctaaggt
    25981 aggggcagca tcaatttcta tatttttagg tatgtttgta ggaaacctat ttttaaatca
    26041 aaaggtattt caaaagggtt ataaattttc agagacagat ttgttatcat attcaatagt
    26101 actattagga gcaacactca gtgtatctac cttaatagac ttaaaagttt caggaatttt
    26161 atttataata ttgcaaatga caataacaat aatagctgca ctttatatag gtaaaaaact
    26221 aggatttgaa gaaaacttta gatttctaat ggcaagtgga aatgcagtat gtggttcttc
    26281 tgcaatagga gcaacagttc cagtggttaa tgcgacagat aaagaaaagg gaattgcagt
    26341 aactattgta aatgttactg gtatatttct tatgttttta cttccaataa tatctcaatt
    26401 tttatatagc catgaacttg taaaaacttc agcaatgata ggtggaactt tgcaatcaat
    26461 tggtcaggtt gtagcaagtg gagcaattgt tggagaaaat gtaaaagatt tggctactat
    26521 ttttaagata gtaagagtaa tatttctagt tgttgttgta ttagtatttg gacatatgaa
    26581 aaatcaatct aatagggaaa ttcttgaaga agaaaaggat gagataaaaa agaaaaaagt
    26641 gactatacca tggtatgtaa ttggattctt tataacttgt gcactttttt caatgaacat
    26701 tataccaaaa gaagtatctg tgttgtgcaa agaaataagt aacaaactag aaataatagc
    26761 tttagcagca attggattaa aggttaatgt aaaagattta gtgaaacaag ggaaagaagt
    26821 ttctttatat ggtttatttg taggtatagt acaagttgta tcagctgtag ttttaataaa
    26881 aatatttata tagcataaaa atagtatttg taat
//
LOCUS       DAYAKB010000049        26772 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.049, whole genome shotgun sequence.
ACCESSION   DAYAKB010000049 DAYAKB010000000
VERSION     DAYAKB010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26772
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.049"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            203..784
                     /locus_tag="ACGI3L_002446"
     CDS             203..784
                     /locus_tag="ACGI3L_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9198146.1"
                     /translation="MMGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLD
                     TAAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPG
                     EISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVA
                     EIYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            823..1401
                     /locus_tag="ACGI3L_002447"
     CDS             823..1401
                     /locus_tag="ACGI3L_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9198147.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1487..2116
                     /locus_tag="ACGI3L_002448"
     CDS             1487..2116
                     /locus_tag="ACGI3L_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9198148.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2106..4865
                     /locus_tag="ACGI3L_002449"
     CDS             2106..4865
                     /locus_tag="ACGI3L_002449"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HFG9198149.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     LKKTA"
     gene            4952..6514
                     /locus_tag="ACGI3L_002450"
     CDS             4952..6514
                     /locus_tag="ACGI3L_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HFG9198150.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6515..7651
                     /locus_tag="ACGI3L_002451"
     CDS             6515..7651
                     /locus_tag="ACGI3L_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFG9198151.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7715..8791
                     /locus_tag="ACGI3L_002452"
     CDS             7715..8791
                     /locus_tag="ACGI3L_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HFG9198152.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDFMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8769..10007
                     /locus_tag="ACGI3L_002453"
     CDS             8769..10007
                     /locus_tag="ACGI3L_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HFG9198153.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10061..11149
                     /locus_tag="ACGI3L_002454"
     CDS             10061..11149
                     /locus_tag="ACGI3L_002454"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HFG9198154.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11177..11968
                     /locus_tag="ACGI3L_002455"
     CDS             11177..11968
                     /locus_tag="ACGI3L_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HFG9198155.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12083..12637)
                     /locus_tag="ACGI3L_002456"
     CDS             complement(12083..12637)
                     /locus_tag="ACGI3L_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9198156.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12833..14035
                     /locus_tag="ACGI3L_002457"
     CDS             12833..14035
                     /locus_tag="ACGI3L_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFG9198157.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14092..15072
                     /locus_tag="ACGI3L_002458"
     CDS             14092..15072
                     /locus_tag="ACGI3L_002458"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HFG9198158.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLSEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            15315..16268
                     /locus_tag="ACGI3L_002459"
     CDS             15315..16268
                     /locus_tag="ACGI3L_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFG9198159.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16258..17214
                     /locus_tag="ACGI3L_002460"
     CDS             16258..17214
                     /locus_tag="ACGI3L_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFG9198160.1"
                     /translation="MKLSLNQKIYFVSILLFISMALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17211..17966
                     /locus_tag="ACGI3L_002461"
     CDS             17211..17966
                     /locus_tag="ACGI3L_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198161.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            18058..19023
                     /locus_tag="ACGI3L_002462"
     CDS             18058..19023
                     /locus_tag="ACGI3L_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9198162.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAETLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            19504..21363
                     /locus_tag="ACGI3L_002463"
     CDS             19504..21363
                     /locus_tag="ACGI3L_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9198163.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(21655..22254)
                     /locus_tag="ACGI3L_002464"
     CDS             complement(21655..22254)
                     /locus_tag="ACGI3L_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9198164.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(22357..23154)
                     /locus_tag="ACGI3L_002465"
     CDS             complement(22357..23154)
                     /locus_tag="ACGI3L_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9198165.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(23267..23372)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(23464..24450)
                     /locus_tag="ACGI3L_002466"
     CDS             complement(23464..24450)
                     /locus_tag="ACGI3L_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFG9198166.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     regulatory      24614..24790
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            24934..26664
                     /locus_tag="ACGI3L_002467"
     CDS             24934..26664
                     /locus_tag="ACGI3L_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HFG9198167.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLSIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
BASE COUNT        10366 a         2889 c         4554 g         8963 t
ORIGIN      
        1 tattaaacat agcttttata catttaataa ggtatgtaaa atctatgtaa aaagtaagaa
       61 atataaacat ttttttaatt atattttaaa aatatcaagc aagttttctt cacaaatgaa
      121 taaaaaatgt tataatatga ttaaagaaaa agataaataa ttagcaagat ttgtttagct
      181 aaaattaaca agggagcgat aaattatggg tataacatta tcaaaaggcc aaaaggttga
      241 tttaactaaa ggaaatccag gtcttaaaaa tattttagta ggtttaggat gggatactaa
      301 caagtatgat ggtggatttg actttgattt agatacagca gcatttttaa caggagcaag
      361 tggaagtgtt actaatgatg gagattttgt attttacaac aatttaaaac atacatctgg
      421 agcagttgag catctaggag ataacagaac tggcgaaggt gatggagatg atgaacaaat
      481 agttgttgat ttatctaaga ttcctggaga aataagcaag atttctttta ctgttacaat
      541 tcatgatgca acagaaagaa gacaaaattt tggacaagta agtaattctt atataagaat
      601 agtagataaa gacacaaatg aagagttaat aaagtatgaa ttaggagaag attttagtat
      661 agaaacagct atagtagtag ctgaaatata taagcacaat ggagaatgga agtttaatgc
      721 actaggttct ggctttgaag gtggtcttgc tgcattatgt ggaaactttg gaataaactt
      781 ataatttcaa ctataacaat aaactaaagg gggatatttt ccatggctat agtattaaaa
      841 aaaggacaaa aaatcgattt aactaaggga aatccaggtc ttaaaaatat aaaacttgga
      901 ctaggatggg atacaaattc atttgatagt ggctatgatt atgatttaga tgtaagtgtt
      961 ttcatggttg gagaatctca aagagttgaa aaagatgaag attttatatt ctacaataac
     1021 ttaaaacatc catctggagc agttgaacac ttaggtgata atagaactgg tgaaggtgat
     1081 ggagatgatg aggaaatatt agtgaattta gagacaatgc caaagcatat acaaaagata
     1141 gctgtaacag ttacaatata tgaggctgct gaaagaagac aaaattttgg acaagtaagt
     1201 aactcatata taagagtatt aaattctgaa aatgatgaag aaatattaag atatgactta
     1261 ggtgaagaat ttagtataga aactgcaatt acagtatgtg agatatataa gtataatgga
     1321 gaatggaagt ttagtgcagt tggagcagga tttgaaggtg gcttagaagc actttgtaga
     1381 aactatggct taaatgttta atttaagcaa tataatatat taaatataaa taacctatac
     1441 aaataatgta taggttatat tatataaaat tttgtggagg tttagtatgt cgattaattt
     1501 atcaaaaggt gataaaatag atttaaaaaa atctaaccca ggactgagta acatacttgt
     1561 aggtctagga tgggaccctg tgcaacaatc tggtggaggt ttttttaaat cgttatttgg
     1621 tggaggacaa gctgatatag attgtgatgc atctgtattt atgcttaatc aagaaggtaa
     1681 attaagtgga ataaaagatt taatttattt tggaaatcta aaaagtgcct gtaaatcagt
     1741 tttgcataca ggagacaatc taactggtga gggtacaggt gatgatgaac aaatcctagt
     1801 taatttggat aaagttccat caaatattca taaattattg tttgtagtaa atatatacaa
     1861 ttgtgtagat agaaaacaac actttggaat gatagaaaat gcctatataa gagttgaaga
     1921 ccaaggtaat aagaaagaga tagcaaaata caatctatct gataattatt ctgaaaaaac
     1981 tactcttata gtaggagcta tatatagaaa agatggaagt tggcaattta aagcaattgg
     2041 tgaaggaaca aaagatgcgg gtcttaaaga agtaatgcaa aatttagaca ggattgagtg
     2101 tgcatatgga atttaataat gatatcaaat attataatgt agataaagaa gaagttacaa
     2161 aagacttatc tgttaatcct gaaaaaggtt tatcagaatc agaagtcaag actagaagag
     2221 aaaaatatgg tttgaatgaa tttactccaa aagaagaggg tagtttttgg gatgatttaa
     2281 aggaaagttt aagtgaacca atgatagtta tcttgattat tgcagcagta gtaagtgcag
     2341 taattgggga aactcatgat gcaataggga ttgtaggtgc tatagcaata ggtatagcaa
     2401 taggtatgat tacagaaggt cgttctaaga aagcagcaga ggctctttct aagttgactg
     2461 aaaacataga agtaaaagta ttgagagatg gggaagtaca tcaaatttct aagagtgaat
     2521 tggtaccagg tgatatagta tatattgaaa ctggtgacat ggtacctgct gatggtagac
     2581 ttatagaaag tataaacctt aaaattagag aagatatgtt aacaggagaa tctgatgacg
     2641 tatctaaaaa gtgtgatgta gtagtttcta tggaagagat agaatctaaa ggagcagtag
     2701 tagtacagga gccaatacct gcaaaacaga taaatatggt gtttggtggc acacttgtag
     2761 cttatggtag aggagctcta gttgtaactt caattggaga taatagtgaa atgggtaaaa
     2821 ttgctcaaaa cttatcagaa acagatgagc aaactccact tcagataaaa cttggaaatt
     2881 taggtggttt gatagccaaa gtttctagtg cagtagcagg attactattt atatttatgg
     2941 ttttccaaat gataagtaag aatgtattaa atgtagatat gtctggaata ttaccgtttt
     3001 tagaatcaat agacccagtt aaaacagcat ttacagtatg tgttgcgttg atagttgcag
     3061 cagtgccaga aggtcttcca actatgataa atatgacact tgcaataaca atgcaaaaaa
     3121 tggctaaaat aaatgcattg gttactaaaa aagaagcttg tgaaacgata ggttctgttt
     3181 ctgtaatatg ttcagataaa actggtacat taactgaaaa tagaatgact gtagaagttg
     3241 catatgttga tggcagatat attgaaagtt cagaagagga aataaatagt tattttgaag
     3301 aaaactgtat gataaactct acagctgatg tagagcacaa tgatggtgat attaagtatt
     3361 taggaagtgc tactgaatgt gcattgcttt tatattacaa aaacgtagat tatagacaag
     3421 ttagaaaaaa ttctaatata gtagctcaaa atccttttac ttcagattca aagagaatga
     3481 cttctgttat aggtcaagat aatcatcatg tactattatc aaaaggagca ccagaagtct
     3541 tacttgaatt atgttcacat attcaaagag gaaaagacat agttccatta actgaaaata
     3601 taaaacatga gattttagaa gaaataaaga aattgcaaat aaaatcaatg agaactttag
     3661 ggtttgcata taaagaaatc tcacaagctg aagaagaagc agcagtaact gctgaaagtg
     3721 atgctatgaa tgtaagtgca atggaaaaca atttagtatt tagtggtttt gttggtataa
     3781 gagacccact tagaaaagat gttatagagt ctgtaaatac agcaaataaa gctggtgttt
     3841 ctgtaaaaat gcttacagga gataatataa atacggcaag agctataggt gaagagttag
     3901 gcctattaaa aaataatatg agagtggttg aagcttcata tatagatact ttagatgatg
     3961 aagaattaaa acaagagata caaagtattt caatcgtggc aagaagtaaa ccagatagta
     4021 aaatgagaat agtttcagct ctgcaaaaga gcggagatgt tgttgcagta acaggtgatg
     4081 gtataaatga tgctccagca ctttcaaaag cagatgttgg tatagcaatg ggtatatctg
     4141 gtacagaggt atctaaaaac gcagcagaca taattttaac tgatgatagt tttagtacca
     4201 ttgtaaaagg tattaaatgg ggtagaggaa tttatgataa cttccaaaga ttcgttcaat
     4261 tccaattaac tgtaaatgta attgcatttt tagtggctat aatatctcaa gttatgggac
     4321 aagagatgcc atttactaca atacaattat tatgggtaaa catcattatg gatggaccac
     4381 cagcactagc attaggttta gagccagtta gggaccatgt gttaaataga aaacctgttg
     4441 atagaaaagc caatataatt tctaagtcaa tggtgtatac aatagtatta aatgcatttt
     4501 atataacagc aatactaatg ttacaatcta catttaattt cttaggagtt gatgaagcgc
     4561 ataagggaac agtaatgttt gcgttatttg cttttagtgc actgtttaat gcatttaact
     4621 gtagagagtt taatgcagat agtatcttcc ctaattttac acataacaaa ttagcactac
     4681 aaataatagt gttgacagga attgcacaag taatatttac tcagctattc caagatttct
     4741 ttaactctgt agcaatggat tttatgacat gggtaaaagt tttatgtgta gcagcaagtg
     4801 taattgtggt taatgaagtt gtaaaatgta taataagact ggtaaaacta aaaaagactg
     4861 cttaaaacaa attttttaga agaaaacaga ctgactcaaa atatgaattt tgggtcagtt
     4921 ctgaataaac atttaaattg ggaggatagt tatgggtgac tcaaaggtat ttgaaaaaat
     4981 attctccagc caatcagata gaggaaatta cactccttca aagggatatc taagttattt
     5041 tatttcgtat attggtttag aagatgaagt tttgtacaat ctcgagatat ttaagacaaa
     5101 acaaaatatt gatagcaaaa aagatattgc tttatttact gatgttatag caaatcctag
     5161 tgattttgat attataaatt attttaaaag tggacttcaa aaatatagaa ctagcatgga
     5221 agatgtagat ataaatattt tgggatttga agagattgat tataaaataa agcaagcaat
     5281 ggatagagtg ttaaaagaag aggaaaaaga atttactaat gatagagtta aacaaaattt
     5341 tatagtgaaa ataatggcat ggataaaaat ttatatcggt gctttagata taaataaaaa
     5401 tgaagctcca aaagtaatat tttatggaga tataaaaaaa catgaagttt atttactctt
     5461 aatattatac ttggcaggtt ttgatgtttt atatcttaat ccaaattcaa agagtaatat
     5521 agatatttta aaatcagaaa gatacaatat agagtttgaa gaagccaaca taatagaaga
     5581 aaaaatttct tttgaagaaa gggttatttt aggggaaaaa atagataaaa gttctgtaaa
     5641 aaaagctttt actgttgggg cagaagcatc aaagcgtata agtgaggaat tgttaaatga
     5701 tgcaggattt ataaaacctt ggcaactcca agatagaaaa ataaaaaatc tacttctaag
     5761 ttcaactgtt gatgaaatat caatatactg gaatcaacca cttaaattaa gaccaggatt
     5821 taagtttaat gatgctattg tagaagctcc aaattttctt tctaagatta atggaatata
     5881 taacgataag aatgaatata ttaagttttt agatttatta agagattcgg aaagttcaac
     5941 atttattgaa tttaatggag atgtagatag attttcaaaa gcttttacaa gagaagcttt
     6001 tagtttatcc tttttattgg attcaaaagg tgcaatagat aaaaactctg ttttaaataa
     6061 taaagattat tccatatcaa cactagcatt gaatcaacaa attatgattt tagagaaagt
     6121 ggaagagttg ttagaaggaa gtatgttttt gaatggttta agtggagaag acaagataaa
     6181 aggtctattt acagtacttc acatggataa gaaatttgtt catatgatga acaatttcga
     6241 ttactcactt ataaacccaa aattgattat atacatgtac aagagtattg tatttgataa
     6301 agaaatagtt tttcttatgc ttttacttag taagattgga tttgatatta tcatattatg
     6361 tccaggagga gaaaacaata tagagaatgt tataaataac caattgattg atgtacacag
     6421 attggataaa atggtatatg accttaaatt aaattcgctt gaaaatgata tacctttact
     6481 taaaaaaatt tttggaaaga ggagacgatt ttagatgggg ataaatataa atagtttttc
     6541 aaaagataag aactctgtag aggttactga aaatttgcct acagcagttc aagaagaaaa
     6601 cttcgatata atggaatata caaataataa aaaaaatgaa ctgagaaagt ctaaggaagt
     6661 tgaggcattg acatctctta tagaagtaga aaatccagat acgattttac agtttggtag
     6721 gaaagcatct gaaggagtag caagagtttc tgatagcctt ttaaatacaa taaaattaaa
     6781 tagaaatgaa gaaaattcta aaatgttggt tcatttaact aaaataatgg acaagtttga
     6841 tttagacgat tttcaagaaa ctaaggaacc aaatttcgtt caaaaacttt tcaaaaaagc
     6901 taataatgcc attgaaatga tgtttcaaaa gtatgaaaca ttgggaggag aagttgagaa
     6961 aattcaaatt gagcttgaac aatacgaaag agatatagca ctttctaata agcaaatagg
     7021 tgctatgtta aatgaaaact ttgagtttta caatgaactt caaaaatata ttgttgctgg
     7081 agaaatggca atagaagaaa tggataatga aatactacct ttctttaaac aaaaatcaga
     7141 gactagtgga gaccaaatgg atgttgtcaa ttatcaagaa ctattaaaag tttatgatat
     7201 gttaaatcaa agagtctatg atttaaggat agcagaaaat atagctatcc aaacaatacc
     7261 tatgcttaga ggtatgcaac ataataatta tggtttaatt agaaaaataa atagtgcatt
     7321 tgtcgtaact ttaccagtat ttaaacaatg tttatctcaa gctatattac ttaaaaagca
     7381 agaattacaa gcaaaatctc taaaagcact tgatgacaaa actaatgaat tattgcttag
     7441 aaatgcacaa aatgtaagta ctcaaagtgc acaaatagct agaatggctg gaacaagttc
     7501 tgttcaaata gaaacattgg aaaaaatgta caatactatc aagtctggta tagatgaaac
     7561 tatgagaata gaagaaaaca atagagcttt aattaaggat aatacaaaga gattggaaga
     7621 attaaatacg actataattt ataataagta gtattatatt aagggctaat ttgtataaag
     7681 ttggctcttt ctatgtatat gaggaggcta gacattgaaa tatttcgatt atatctgcaa
     7741 agatgatttg gagagaattt ttttgaagga gccagaagat tttagtgcta agactgaaaa
     7801 agatgtgttg aaatatgcac tgggcgcttt tttatacgtt ccagctactc aatataatat
     7861 gatttataag agtattatag gggatgttaa gggagttaga ccattagcta tttgtttaga
     7921 agatgctgtt ggagtaaatg gagagttgga ggctatagaa aatcttagat taattttaaa
     7981 aaatattagc aatgaaagta taactaataa agatggaata ccactaattt ttgtaagaat
     8041 aaaagatgtg gagcaactgt tgagaattaa agagattata attaaaaata gtcattttat
     8101 aacaggaata ttaattccta aagcaaattc ggagttaatt gaaaattgta tagaagcttt
     8161 agattttatg aatcttcaag atatgtatgt tattccgata gtagagacaa aagaatttat
     8221 atataatgaa aaaaaagaac ttagttttac taatttgtac aatgctattt taagacataa
     8281 gtcaagaata ttaagcatta gagtaggcat aactgatata ttagggatgt atggtataag
     8341 gagagataaa aacttttcta tatataataa tttgatttgt tcttcattta tattagatat
     8401 aatcacatat cttcaaagac cagagttaga tatacctata agtggtggag tatcagaatt
     8461 ttttgatatg acgaataagg atataagaaa taagtatata gaagaaatat tattggataa
     8521 atatcatgga ttaattggaa agaccgtaat tcatccaatg caaattcaaa ttgtacaagc
     8581 gctatctaca gtatcatatg aagattttac tgatgctttg gatatactgg atagtacaga
     8641 cagtaagtat ggtgtgagca agggtgtatt aggagagaga atgaatgaaa caaatccaca
     8701 ttttttatgg gctaaaaaaa cattgattct atctaaaata tatggtgtat taaataaagg
     8761 agtagactat gaagaattgc ttaaatttta attgtgagat tgacattatt gataatccat
     8821 tgaatttaga actaaatgat tttttagacg taggaataag aaataatagc aaaagacgtt
     8881 ttttgtttat ctcaaagaaa ctcggtaaac atttagcatg taagccaagt gagatggata
     8941 atttgggaaa attaatggct acaatttata atgaaaaaaa taaggaagaa tcaaatggta
     9001 ctgttatagc ttttgctgaa actggtacag ctgttgggca tagttttttt gattacttat
     9061 gtggagatta tgaatttatt catactacta gagagcagtt tgacgagtta gaaaatctgg
     9121 aatttttaga ggaacattcc catgcaacag accagaattt atactttggt atgcttaaca
     9181 actttaaatt tggagatgag ataatattgg ttgatgatga gattaccaca gccaatacat
     9241 gcatgaatat aattaggaaa attcaaagca tttatcctaa aaagaaatac actatatgct
     9301 caatactcaa ttgggtaagt gatgaaaatt taagtaaagt tactcgttta gaaagagagc
     9361 tagattgtaa gatagatttt gtatacttat ttaaaggaaa ctttaaattt tatatagatg
     9421 aagatattat ttcaaattac aacgataatt atagtattac taaattagag actatttcaa
     9481 gtgataaagt aaatttagta gtaaatcata tttatgttga tttagaagat tatattggaa
     9541 ataagaaata tgtaaaatat acaggaagat ttggaattaa tagaagagaa caatttagat
     9601 taaaagaaat cgttaagaga gaaagtaaaa aaataactat ggccagtaaa gaatctttaa
     9661 aaaatgaaaa agaaaagatt ctatttttag gtactgaaga atttatgtat atacctatgc
     9721 tgtttgcaaa agaaaaagaa aatcaatatg atatatacta tcattcaaca acaagaagtc
     9781 caattattaa tattgataag aataattatc ctattaaaag taaatttatg ctaaagagtt
     9841 tttataatat agatattcaa aattatattt acaatataga taaacataat ttttctaagt
     9901 gttatttatt tgtagagctg aataaaagtg aaaattctta tctagaattt attgatataa
     9961 ttaaaaaaac aagtataaaa gaattaacta tagtatgttg tagctaaagt gttttaacag
    10021 gataaaatat atcacgattt taagatagga gttgagtcat atgagagatt ttagcacgta
    10081 ttctaaagat gatgttattt ttttattaaa agatatatca aatttaattg aagaagaagg
    10141 aaataaagaa agagaattaa aaatacaaaa tggtagacat tattcagaaa tgataccaat
    10201 agagtatgaa gttagtgaag attatctgaa tttatatcat gagaaactaa gagaaaataa
    10261 agataaactt gcattttcta taggagttat gtgtgaaaaa ataattaaaa aaaatggaaa
    10321 tgatgtagta ctagtttcac ttgctagagc aggaacacct attggtattt tggcaaaaag
    10381 atatataaga agcaagtata atataagttt acctcactat acaatctcta taataagaga
    10441 taagggaata gatatgaatg caattgaata tatagtaaag aatcatccga gctcaaaaat
    10501 tcaattttta gatggatgga ctggtaaggg aactatatca aaagaacttg aaaaagcatg
    10561 tgatgaactt aatgttaaat ttaaaaaata ttttgactca acacttgctg tattagctga
    10621 ccctgctgga tattcaggac tttatggaat tagagaagat ttcttaatac caagtgcatg
    10681 tttaaattca acagtttctg gtttagtaag tagaactgta ctaagagagg atttaattgg
    10741 taaaaatgac ttccatggag ctaagtttta tagacattta aaagataaag atgaatctat
    10801 gaactatatc gaaactatag aagaatgttt taaaaatcaa tttaagaata tatctgatga
    10861 agttgaaaac tgggaaagtg acattataac aagagatgga tactttgatg ttttaaatat
    10921 aaaagaaaag tataacataa cagatattaa ctttatcaaa ccaggtgtag gggaaacgac
    10981 aagggtttta cttagaagag ttccgtataa gattcttgtt aaagacttaa atgataaatc
    11041 tttagaccat atattcatat tagctaagga gaaaaatgtt gaagttgaac aaatggattt
    11101 aaaagcctat aaatgttgtg gaataataaa aaatatgaaa gatatttagg aaatatatta
    11161 gacaggagaa tattgaatga ttgttttttc agatttagac aggagtatca tttactccaa
    11221 taaattttta aatgctgata gtaaatatac taatatagaa atttataggg aaaaagaaat
    11281 atcttatata tctttagata ctataaattt aataaagcaa atacaatatt atggtatgtt
    11341 tatacctaca actactagaa cagtggagca atttaagcgt atagaattta ataaatatgg
    11401 gatttatttt ccttggagta taacttcaaa tggaggagtt atacttaaag ataatgaaat
    11461 attgaaatca tggagtgaaa aaatagataa actaaaatgt gattatgagc ccattgaaag
    11521 tatgattcat aaatttaaag actatttgaa tgtagatgga ataactaatt ttaaagttgc
    11581 agaagataca tttttttata tagttgttga tttatcaaga tttaatttgg attcaatcaa
    11641 agaatataca aatatattgg aatcaaaaaa ttggaagttt tatgtgagtg gcagaaaaat
    11701 atattttata ccaaaagaaa tttcaaaaga aaatgctata aaatacttga ctaaagaatt
    11761 aggaatagaa tatttttatg cagttggaga ttctattatg gactatggta tgcttaatat
    11821 ctcaaataaa tcctatgtat tgaagcatgg tgatataaat aaaaatgaaa tagaaaattc
    11881 atttatatca agttctttca atggaatgag tggaactgaa gagatactat ctaacatttt
    11941 agacgagaac tgcctactta atatataatg actgatatat aaataataaa ctagaaaaat
    12001 ctgaaataaa ttatagtaaa gtttatcata ctaatttatt tcagattttt atcaatttat
    12061 atttaagtaa gaactcaata tgttaaaatg aaggtggagt cattgcccag actgagatac
    12121 atacctcatc atcataattt tcatacacat gtggtatagt actgttaaaa taaaaactat
    12181 ctccttcctc caatagatat tccttatttc caagtgttat cttcatttta ccttttatta
    12241 tatagccaca ttcttctcct tcgtgtgtca caaattcact gtttttttgt gtatgaccat
    12301 ctagtgtaac aagtataaat tctatttttt tcccagataa attaggaaca agaagttcat
    12361 aaaattttgt agaatcatta gttactattt tttttcgatt atttttcttt actactatat
    12421 cagagtcttc tcttccaatc tcttcaaaaa aataacctat atttatatca agagcttttg
    12481 atattttcca cattgctaca atagatggaa caaccatatt acgctcaatt tgacttatta
    12541 agcctgtact taaatctgaa ttttttgcta aagtagagat acttatattt ttagattttc
    12601 taagagatct aattttgctt ccaacatcta tattcattag atacaaaccc cctcagacat
    12661 gattataaca tataatttat aaagattaat aaaataaaaa aaaagtttta caatacaagt
    12721 attttttatg ctatattgaa ttttctgaaa agatgcatta taatagtatt aatattcaat
    12781 atattgaata ttgataacga tattttaatt taatgaaatg gaggtaatta agatgaagag
    12841 ttttgtaagt cctgataata tttgggtatt atgggcagtt gtaactggat gggcagcatt
    12901 tagtatttat ttggaacaaa agtacaattg ggcatcaaaa gtgtcgggag caataatagc
    12961 tcttgtagga gcaatgttat tatcaaatct aaatattata ccagtagagt ctgttgtata
    13021 tgaccaagta tggggatatg ttgttccttt agccatagct ttattgttat atcaatgtaa
    13081 cattaaaaag atatggaaag aaagtggaag attgctcatt atatttcttg taggttctgt
    13141 aggaactgta cttggagcta tgattggatt tttagcatta aaaaatgtag taccagattt
    13201 aaatattgtt gcagctatga tgacaggttc ttatataggt ggaaatgtaa actttgctgc
    13261 tatgtcaggg gcgtttgatg cgccaggaga attagtatca gcaacagttg tagcagataa
    13321 tcttttaatg gcattatatt tctttgtctt aatagctata ccatcaattg gattttttag
    13381 aaaacatttt aaacatccac atgtagatga aatggaaagt ataggtataa ctgaaggaga
    13441 aacagtagca gcaaattatt ggggaagaaa agaaatatct ttaaaagata tagcaatagc
    13501 cattggtagc gcctttataa ttgttgcagt atctgtagaa ctatcaactt ggtttaaagc
    13561 tataatacca ttatcaaatc cttttttagc aatgttaaat actttatttg gaaatcaata
    13621 tctaataata actactttga ctatgttgtt tgccacattt atgcctaatt tctttggtga
    13681 tataaaagga gcacaggaat tgggtacatt tttaatatat atattctttg ttgtagtagg
    13741 tgttcctgct tcaataacat taataattca aaaatcacca ttactacttt tatactgcgg
    13801 aataatggta ctaataaaca tgctagttac atttatagtt gcaaaaatat ttaagtttag
    13861 tttagaagaa gctattcttg catctaatgc aaatattggt ggtcctacaa cagcagcagc
    13921 tatggcaata tcaaaaggat ggtctaagct agtagggcca atacttatag ttggaacatt
    13981 tggatacata gtcggtaatt attttggtct tttagtagga aatattttga tataatttta
    14041 cgtgaaaaaa agttgtttat tagaaagatt tttatttaat tggaggttgt tatgattttc
    14101 gatggacatt cagatacttg ggcagatgta acaataagaa ggcttaacgg ggaaaaagat
    14161 gtatttagaa gaatccatct tgataatttt aaaagagcaa atatagaagg agctattttt
    14221 gtaatatgga tagacccacc atatgataaa gagcctgaaa aaagagttaa acaaattata
    14281 agttctataa aagatgaaat tgaagatatg aaagatgttg taaacatagt aaaaaaatat
    14341 tcagatatag ataaaggtat aagtgaaaac aaaataaata ttttaattgg tcttgaagga
    14401 ttaagccata ttggaagaaa tatagattta ctagattatt tttataaaga agttggtgca
    14461 agacatgcat cattaacttg gaatgaacag aatgaacttg ctacaggatg tttaggggat
    14521 gaaaatcgtg gtttaagtga aataggcaaa aaagcagtca ataaaatgga aaaattgggc
    14581 atgatagtag atgtgtcaca tttaaatgaa aaatcatttt gggatttaat gtctgttgca
    14641 agtaagccag ttatagcttc tcattctaat gctaggagtt tatgtgatgc taaaagaaat
    14701 cttacagata atcaattaaa agaaatttca aatacaggtg gattagttgg aataaatagt
    14761 tttagaggat ttactaatag taatcctaag aagcaagatt taatacattt ggttgaccat
    14821 atagactata tggtaaatct tataggtata gaacatgtat cttttggttt tgattttagt
    14881 gattacttag ggaaagagac tataggttct tttactggaa atgctagtgt gccaagtgta
    14941 gatggtcttg aaagcacaca tacagcacag aacatagtag tagagcttga aaatagaggt
    15001 tataaaaaga aagatataga gttaatctct agtggtaatt tttataggct ctttaaagat
    15061 atactaaaat aatataataa agaacttaaa tttataaaat agtatattta tacaaataat
    15121 atctacatat ttaaattggc gttcataatt tattaaattt taatgttact agaagtttca
    15181 attctagtaa cattttttat gttaaaaaca gatatagata tgtattgaca atgataatta
    15241 ttattgataa actataaaag tgaaaatgat aataattttc attttaatta ataaaagatt
    15301 tttaaggagg gagaatgaag aaaaggtatt tagtcatagg aataataatt ttgtcttatt
    15361 tttctttatt tataggagct gaagatataa atataatgca tatatttgcc aaaaatcagc
    15421 ataaacttat gatatttatc atgagtagaa taccaagatt aataagtata ttgattgctg
    15481 gtgtaggaat gagcatagca ggtcttataa tgcaacagat aagtaagaat aaatttgtat
    15541 cacctacaac aggtgctaca atagatgcag cacaatttgg gatagtaata tgtatgcttt
    15601 tagtaccaac tgcctctatt tttacaaaga caataatagc atttgtattt tctcttgtag
    15661 ggacttttac gtttatgaaa ataataggga agttacaatt taaaaatata atctttgtac
    15721 cattagtagg tataatgttt ggaaatataa tagggtctat gacggatttt atcgcgtata
    15781 aatacgattt gagtcaaaat gttagttctt ggatgcaagg tgacttttct atgatactta
    15841 aaggaaatta tgagatatta tatatcacaa taccccttat aatattagca tatatttatg
    15901 caaataaatt tactgttgtt ggtatgggta tggattttgc gacaaactta ggtcttagtt
    15961 acaaaagaat tgtcaatata ggtctgataa tagtagcact tgttacagta tgtgtagtcg
    16021 ttacagctgg taatatccct tttataggtc taatagttcc aaatatcgta tccttgtaca
    16081 tgggtgataa tataagagca agcatatggt atactggttt acttggagcg atatttgtac
    16141 ttatatgtga tatttttgga agaattatta tttatccata tgaaatatct atagggctta
    16201 cagttggagt tataggaagt atactattcc tttatttaat attaaggagg aatgtgaatg
    16261 aagcttagtc tcaatcaaaa aatttacttt gtaagtatat tactattcat atcaatggca
    16321 ctttttataa tttatggaat agacatgaat catttagaat atgcattatc acaaagaata
    16381 ccaaaaatat ttgctatggt attaggtgga ggatgtatag catttactac tgtagtgttt
    16441 caaacaatta caaacaatca aatattaaca ccaagtgtac taggtttaga ttcattgtat
    16501 gtaatgattc aaactataat agtattcata tttggttcaa gcagtagtct gattataaat
    16561 gaaaattata attttattat taatgtagct atgatgattg gagcttcatt gttattatat
    16621 aagacgttat ttgaaaaaaa taaaaataat attttctttt taatcctagt aggaatgata
    16681 tttggaacct tatttaaaag tgcaacaaca tttattcagg taatgataga ccctaatgaa
    16741 tttttagctt tacaaactag tataatggca agtttaaaca atataaacac taatgtattg
    16801 ttaatagcat ttataataat tattgccata atacctttta tatatgatga aataaagtat
    16861 ttagatgtat tgtcgttagg taaagaacaa gcaattaatt taggtgtaga ttttgataaa
    16921 gcagttaaaa aaatgataat attaatagca attttagtct caatatcaac agcacttatt
    16981 ggacctatga catttttagg acttttactt gctaatataa caagagaaat ttttaaaaca
    17041 tataagcata catacttgat ttcgggttct atgttgatag ggatgattac attgataata
    17101 ggtcaatttt ttatacaaca tgtatttaag tttgatacaa ctttaagtgt agtaataaat
    17161 tttataggag gaatttattt tattcaatta ctattaaagg gggcaaatag atgatagaga
    17221 taaaaaatat atttaaaaga tataagaata aaaatgttgt agatgatgtc tcttttagta
    17281 tagaaaaggg aaagataaca tcttttatag gaccaaatgg agctggaaaa agtacagtac
    17341 tatcaatagt tacaagactt ataggaggtg atggtggaga agtaataata gaaggaaaaa
    17401 gcttgactaa ttatagcaat aaagaattag caaaaaaaat agctattctt aaacaatcta
    17461 acaatataac tttaaagctt acaataagag aattagttgg atttggaaga tttccatata
    17521 gtgaaggtaa tctaactaaa gaggatgaaa attatattga tgaagcaata gaatatatga
    17581 agttgactga tatacaacat aagtatttag atgaattgag tggaggtcaa agacaaagag
    17641 cttatatagc aatggtaata gctcaagata cagagtacat attacttgat gaaccactga
    17701 acaatttgga tatgaaccat tccgtacaga tgatgaaggt acttagaggt ctttgtgatg
    17761 aattagataa gactatagta ttagtaatgc atgatataaa ttttgcatca tgttattcag
    17821 ataatatagt tgcattaaaa aatggaaaag ttgaaaaagt aggtcgtaca gatgagatag
    17881 taaatgaaaa agttttagaa gatatttatg agatgaattt taacattaag aatataaatg
    17941 gaaatcgaat ctgtatttat ttttaaaata ttgtatatga aaataaactt gctatatgat
    18001 tttttataaa gtttttaaat taaaataaag attaatagga gagaggaaaa tattgatatg
    18061 aataaaaaag cagcaatagt agcagcagta gctattatag gattagtgac agtgtttgca
    18121 ttaggtggaa gtaaaaagaa tgaatcaaaa acatcagaaa attcaaataa tactatgaag
    18181 ataactcata acttgggaga aacagatgta aaattaaatc ctaaaaaagt agtggtattt
    18241 gattattcgg ctttagatac aatggatgca ttaggtgtag ctgagacttt agtaggactt
    18301 ccaaaagcga gtttaccagc atccttagaa aaatataagg atgacaagta tgcagattta
    18361 ggaggattaa aagaaccaga tttagaaggt ataaagtcgg caaatccaga tttaattata
    18421 ataaatggaa gacaagaaga tttttatgag caattgtcaa aaatagcacc aacaataagt
    18481 acaagtaaag atgataagaa gtacttagaa tctgttaaaa ataatataga caaaatagca
    18541 aaaatatttg gagtagaaga aaaagcaaat caagaattta gtaaaattga aaagaaaata
    18601 gaaactttga ataaaaaagt aacagataaa aatttaaatg ctttaactat aatggtaaat
    18661 gaaggtaatt taagtgtatt tggtgaagaa tcaagattta gtatattata caatagtttt
    18721 ggatttgaaa ataaagataa aaatataaaa gaatcaagtc atggacaaaa tattactttt
    18781 gaatatatag ctaaacaaaa tccagaagtt atgttcgtta tagatagagg aatagctact
    18841 ggcagtgatg taaaagaaag ctcaactgca aaatctgttt tgaacaatga tataataaaa
    18901 tctatggatg catataagaa tgataatata atatatttag attcaccaac atggtatgta
    18961 aatgatggtg gtctaacatc tttaaataaa atgatagatg atgcttcaaa agcggtaaat
    19021 taataatccg atataaccaa aatgtatttt ttataaaatg attatcaaat aaactaggag
    19081 tttttaagaa ctcctagttt attttttgca taaaaaagat atagtttaaa caataatatt
    19141 atctataata agataaatct attcaaaatc taataaaata tgaagttata ctagacaaaa
    19201 agaataactc ttaaatataa ttaagttata taataatata taattataat gatataattt
    19261 taataggtgg tttgtaatta aaaagtttat aaattatatt aatagtaata atctataaga
    19321 acttatatat tagaaaaaaa tttttgtata tataaaggac tctaaagatg aactatgtaa
    19381 aacaaggttt atatattcta attgtataga aaaatttatt gtaaacgcat gtatattatt
    19441 agaaaaaata gtttggaggt attcaataaa cataaaaaac aatatagggg ataaaggtgt
    19501 tttatgaaga gatttttgag gagaattatc ttagttttat ttattttgtt gatttttata
    19561 agttttattt ctattaaatt aattcataat gttggagatt atggaaaatt gattaattat
    19621 gttgggattg ttcgtggagc tagccaacgt ctaactaaac tagagatgaa tcatcaacca
    19681 aatgatgaat taatagaata tattgatgaa atcctacagg agttgattac agggcatgga
    19741 gattatggtt tagtaatcac tgattgtaat gaatacaatg aggacttact tttattagaa
    19801 aaaaagtggg aagatttaaa tattgaaatt aaaaaagtaa gaatgaaaga acagaataac
    19861 cagttattaa gtataagtga agagtttttt tctcttgcaa atgatacagt gtttaaaata
    19921 gaaaactttt ctaaagaaaa aagtaattac ttaatgactt taataataat tatatctatt
    19981 ataggtatat tagcatgtat catattgatt ttacaatata gtaaaaaaat ggttagactg
    20041 gaaaaattaa atgtagattt aaaaaatatt gcatataaag atgaactaac aggagtaaat
    20101 actatagaaa aatttaaatt ggatgcaaat caaaatattt gtatacataa ggataagaaa
    20161 tttgctgtat tctatattga ttttgaaaac tttaaataca ttaatgatat atttggatat
    20221 gattatggtg acatgatact gaaaagatat gctaatctta tgatgaatga catagggaaa
    20281 tatgaaatat ttgcaagaga aattgcagat agatttgttg cgttaagatg ctatgtagat
    20341 aaggaagatt tagtggtaag acaacgagat gtagacaatg aactaattaa tataacaaat
    20401 gaaattaaaa ataaacatag tattactgtt gttagtggaa tttgttgtat tgaagatgta
    20461 aatgaaaaat taagtataga tggtttaata aatagagcaa attttgcaca aaaaactgtt
    20521 aagaataaac caggtactaa ttatgctttt tataatgaca gtattcgtaa aaaaatgatt
    20581 gaagaaaata ctatcaaaag tagaatacat gaagctattg aaaaaagaga atttatagtt
    20641 tatttacagc ctaaagttaa tttacatagt caaaaaataa attgtgcaga agctttagtt
    20701 cgttggctta ctccggataa aggtattata tctccagcaa tatttattcc agtacttgag
    20761 aagaattttt ttattgcctt agtagataag tatgtttttg aggaggtttg taaatggatt
    20821 agaaagaggt tagatgaaaa taaacctttt gttcagatat cagttaatgt ttcaagaata
    20881 caattttata acactaaatt tgtagaaact tattccaata tacaaaataa atacaggata
    20941 cctaaaaata ctatagaaat tgaatttaca gagagtgttg cttttgagaa tcaaaaacat
    21001 cttttggaaa ttatacatga tttgcatgaa aatggattta cttgttcttt agatgatttt
    21061 ggaaaaggtt attcgtcttt aagtgtttta aaagatttac catttgatgt tttaaagctt
    21121 gattctatgt ttttcaaggc tagtttagat aaagataaag agaaaatagt aataaaaaat
    21181 attgtacata tgttaaaaga acttaatatc acaactgttg ctgagggcat tgaatgcaag
    21241 gaacaagttg aatttcttag ggatattggg tgtgatttag ttcagggatt tgtattttat
    21301 aaaccaatgc caatattaga atttgaaaaa atattggata aagagtttgt ttataatagc
    21361 taaaatgtac tttataaaat atgaactaat taagtaaaat tattttgtac tgaataaatt
    21421 tttactttat ttacagaata atgattattt acagaaaagc gcgaaaagtg tattccttta
    21481 agtgtgggat ggatagcaca aatagaggag aaaaaatatt ggccatataa gaatgcataa
    21541 taatataaat atttaaaagg tcagcattat ataaaaatta aaaagaaaat aaataatttt
    21601 tctataaaaa agagactatg agaaaattta ctcatagtct cctaaataat gtatttattt
    21661 tcttcctgca acccatttta atccccaatg aaattcagta tccatttctc tatgaccttt
    21721 gaagtattta actacttttt caacactgaa tgtctcatca tttacatttt ctatcaatgc
    21781 tattgaacac atattatagc catttttatg ttcatcaagt ttgacaacta agtctgaatc
    21841 ttgtttttgt ttgattgtta caattccatc agcttcagac cagttagcta caccttcgta
    21901 tataaaagca taaataagta ttctttttat atcttttatt ttattaccat ttattcttaa
    21961 attttctcct tgtgtattac ttcctgttct gtcatctcca tctaattgag caaaaggtgg
    22021 attgtctaaa ctaccaaagg catttcctaa tgcttgaaca gcacctttta caccattttt
    22081 catctcaaat aggcaaccca aatctaaatc tatattactg cttcttaaag agccaaaaaa
    22141 accctttttt tgtacttttt gattccaatt taaattaact aaaatttcac ctaaatcgct
    22201 attttccttt tttgtaaggt ttattttttg tccctttttt aattctatag ccatagtaat
    22261 cttcctccac aaacatagat ttatttaaat ggtagcactt aataagtcaa tattcaacaa
    22321 gattagaata ataatattaa aattatacta aatatactaa aaagtaggaa tcacaatacc
    22381 tttgtatttt tcttcaatta agcttcttgc tttatctgat gtaagaacat cttgtagaac
    22441 tttaatcttt tcactgtctt tatcttcagt tctaaatgct aaaagatttg catactcgtc
    22501 atttatagga gctgtataaa ttccgttttt cttggcatca agaccagcag gtacagcata
    22561 agtagtatct ataaatgcag cagtcacatc tggaagagaa gatggaattt gagcaatatc
    22621 taactctttg aattgtattc cctttggatt ttctattatg tccttaggac taactaatcc
    22681 atccccttta ggtaacgtta aaagtccaat actttcaagg tatctaaggt tcttagaaca
    22741 agaagatggg ttattgctta ttgcaattgt atctcctttt ttaaattcat caacagattt
    22801 tatcttataa gagtaaagta ttgctgggca tacatatagt tttttaccag ccattatttt
    22861 gtaacctttg gccttaacag cttcttttag ataaggttca tgttgaaata gatttgcatc
    22921 aatttcacca ttatttaaag cttcgtttgg aagtatgtaa tcatcaaagt ttttaacttc
    22981 taaagtatat cctttttctt taataagtgg ttttaattct tctaataact ctcctcctgg
    23041 aactaaagta gcaccaacaa caattttttt atcatcttta gctttagaac atccaaccac
    23101 agctaaagtt agtactagac ataataacaa acataataat tttttgaatt tcatataaat
    23161 tccctcctga atataattga ttagttaaaa ataaaatacc attctttatc acactgcaaa
    23221 ataaaaataa gcctgagttt aaactcaggc tttaaaagct aatttagact catctttcag
    23281 tataatactg caggatttag caccaatgta tataaaaata tactggttgc tgggtttcat
    23341 agggccagtc ccttcaccac tctggataag aagtatcaat ttttaattat gttataaata
    23401 ttatcatgat tttttacgtc tgtaaacata attttataaa tattttaaaa tctttaatgt
    23461 attttattta acacctaaaa ttccagaaac tagaatatca gtatcagcac ctaagaaata
    23521 gtcatttatt tcaatagaat ccagagtatt tctcaaagca ttttcttcat gccttatacc
    23581 aataagttta ttttctacaa atgcaacatc acattttcca aaaaaatctc caaaaaattt
    23641 tatactagtt attatgcctt tatcaacatt taaattaaac tcaacatttc caccagaata
    23701 ttttaattca tttgaaagag tatattttgg tgaattacca aaattccaat cccaagtttc
    23761 gtattttgat ttagtaagct tttctatttg ttttatatca tgctcactca aacaataatt
    23821 agtattatca gtatttgttt tagaaagata atccattata gcatctttaa attctaatat
    23881 gtccattttt gaatgtaaat gttcacttat attggttaca cgagatttta cagattttat
    23941 tccttttcct tcaaatttta taggtttaac ctttaatgct tttgagaggt catttatttc
    24001 agatgaaaat aaaagagtcc catgatgcat tactttgttt ttgtagttgt attgagcatt
    24061 tccagaaaat ttcttgccat ctataagaag gtcatttctt ccagaaaatt cggcattgac
    24121 atctagtgtt ttaagtaaat ctattatggg ctgagtgaat cttctgaaat cactaaaatt
    24181 attattgtta caagctataa atgtaaaatt tatatttccc aaatcatgaa atacagctcc
    24241 accaccagac tgtctcctaa cgacaggtat agaatattct tttatatatt ctaaatttat
    24301 ttcagaaagt gtgttttggt tttttccaac aattatagaa ggttcattcc tccataaaat
    24361 aaataagtct tcatcaaaat tttttagaag atattcttcc attgctaaat taaaataagg
    24421 gtttgttttt tcattataaa ttaataacat taaagtagtt cctccataga attgataaaa
    24481 tttttattat gaatacaatt aattttataa ttcgacaata atataaaaac tcctttaaat
    24541 tagaaatttt aaaaactacc ttgcaaagtt taaataaata atatatactc aaaatatgtt
    24601 taataaaagt gaatagaagg gtagaggcgc aataatctat cagtactaat aaggagttaa
    24661 gcacagagag ttattaggaa aggagatatt gccgaagttt tataatcgat gctttaagat
    24721 tatattgctg ggggtacata gaaaatatgt acaactgtca caggtttatt tgtggtgagc
    24781 tatcatttaa ggaattatat tatatttatt tttactattg ttgatatatt gtaatgttta
    24841 agccttgagt gtttaccact caaggctttt ttagttttat tgtaacataa taccctgtac
    24901 agttcacaaa attaaaagga gagggagatt tatatgagga acaaaaaaat taatattatt
    24961 tttctgacga caatcatgtt cataatgtca acagtaatgg tttttgcaga agaagatata
    25021 gacactattg cactagccaa tgcagaaaaa tttgggattt taactttaat accaccatta
    25081 gttgctataa tactcgcatt tataactaaa aacgtaataa tttctttact tataggtatt
    25141 ctttctggta gttttataat taaagctagt ggtattaatg tttttgcgac atttatacag
    25201 gcatttttag atttagtaga tagagcttta gtatctttag cagacccttg gaatgcgggg
    25261 ataatactac aggttttgtc aattggagga gtaataaatc ttgttgctaa aatgggagga
    25321 gctaaagcta tagctgaagc acttgctaaa agagcaaagt cagcaaaagg gacacagctt
    25381 ataacatggt ttttggggct tttagtattc tttgatgatt atgccaattc actaatagta
    25441 ggtcctatga tgagacctgt tgcagataaa atgaaaatat cgagagaaaa gctagcattt
    25501 ataatagatg ccacagcagc accagttgct ggtttagcta taatatctac atggataggt
    25561 cttgaggttg gtttaataca tgatgctttt gaaagtataa gtatagatgt agatgcattt
    25621 ggtatatttt taaatacaat accatttaga ttttacaata tattaatatt agctttcatt
    25681 gtaatatcag cattattatt aaaagaattt ggtccaatga gaaaagctga gataaaatct
    25741 agaagtagaa aaattagtat agaccttgat gaaggcgtag aagagttgga tgatttagct
    25801 ccaaaaaatg gagtaaaatt gagtgtatgg aatgctataa tcccaatagg aacattgata
    25861 atagttgcat tagcatcatt ttattatagt ggatatacat ctataatggg aggagacgat
    25921 aaggctctga tacaactatt tacaaattct ccatattctt ttgaagcaat aaaagaagca
    25981 tttagtgcat ctgatgcatc tagagcatta ttccagtctg cacttgttgc aagtttagtt
    26041 gctattataa tggctgtagt aaaaaagatt tttacaatat cagaagcaat tgatgtttgg
    26101 atagatggaa tgaaaagttt agtaatcact ggtgtaatat taatacttgc atggtcatta
    26161 agttcagtaa taaaagagtt aggtacagct aaatttttaa tacacctact atcaggttca
    26221 ctaccaccat tcttattacc aagtttaata tttggtttag gagcaataat atcttttgct
    26281 actggaacag cttatggaac aatgggtata cttatgccac ttgcaattcc attagcatac
    26341 tcattaaatc ctgatatgtc ttatgtaata gtaagtacta gtgcagtttt aacaggtgca
    26401 atatttggag accattgttc tccaatttca gatacaacaa tactttcttc aatgggagct
    26461 ggctgtaatc atatagacca tgttaacact caaatgccat atgctatatt tacagcagta
    26521 atcactattg tatttgggta tataccagct ggacttggat tgccaatata tatagtatta
    26581 ccagtggcaa tagctgctat atttgtaggt attcaaataa ttggtaagaa agttgatgaa
    26641 gcggaaatag aacttgtaga ataaagatat aaataagttt caccttttat tatcactatt
    26701 ttgttagttt ttagataatt ttaaaaagtt attgaaaata atggcgaaat atagtaaaat
    26761 aaaagagtga ta
//
LOCUS       DAYAKB010000050        25030 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.050, whole genome shotgun sequence.
ACCESSION   DAYAKB010000050 DAYAKB010000000
VERSION     DAYAKB010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.050"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(80..688)
                     /locus_tag="ACGI3L_002468"
     CDS             complement(80..688)
                     /locus_tag="ACGI3L_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFG9198168.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(797..3535)
                     /locus_tag="ACGI3L_002469"
     CDS             complement(797..3535)
                     /locus_tag="ACGI3L_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198169.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLKDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3683..4474)
                     /locus_tag="ACGI3L_002470"
     CDS             complement(3683..4474)
                     /locus_tag="ACGI3L_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9198170.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4510..5166)
                     /locus_tag="ACGI3L_002471"
     CDS             complement(4510..5166)
                     /locus_tag="ACGI3L_002471"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFG9198171.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5159..6124)
                     /locus_tag="ACGI3L_002472"
     CDS             complement(5159..6124)
                     /locus_tag="ACGI3L_002472"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFG9198172.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6230..6336)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6626..7570)
                     /locus_tag="ACGI3L_002473"
     CDS             complement(6626..7570)
                     /locus_tag="ACGI3L_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9198173.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7681..8148
                     /locus_tag="ACGI3L_002474"
     CDS             7681..8148
                     /locus_tag="ACGI3L_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6194 family protein"
                     /protein_id="HFG9198174.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNNDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8318..8917)
                     /locus_tag="ACGI3L_002475"
     CDS             complement(8318..8917)
                     /locus_tag="ACGI3L_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198175.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            9163..9759
                     /locus_tag="ACGI3L_002476"
     CDS             9163..9759
                     /locus_tag="ACGI3L_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HFG9198176.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(9857..10816)
                     /locus_tag="ACGI3L_002477"
     CDS             complement(9857..10816)
                     /locus_tag="ACGI3L_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9198177.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10850..11581)
                     /locus_tag="ACGI3L_002478"
     CDS             complement(10850..11581)
                     /locus_tag="ACGI3L_002478"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198178.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(11574..12344)
                     /locus_tag="ACGI3L_002479"
     CDS             complement(11574..12344)
                     /locus_tag="ACGI3L_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198179.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGANKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(12429..13139)
                     /locus_tag="ACGI3L_002480"
     CDS             complement(12429..13139)
                     /locus_tag="ACGI3L_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HFG9198180.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(13319..13471)
                     /locus_tag="ACGI3L_002481"
     CDS             complement(13319..13471)
                     /locus_tag="ACGI3L_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFG9198181.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(13497..15653)
                     /gene="feoB"
                     /locus_tag="ACGI3L_002482"
     CDS             complement(13497..15653)
                     /gene="feoB"
                     /locus_tag="ACGI3L_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFG9198182.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(15753..15974)
                     /locus_tag="ACGI3L_002483"
     CDS             complement(15753..15974)
                     /locus_tag="ACGI3L_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9198183.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(15987..16199)
                     /locus_tag="ACGI3L_002484"
     CDS             complement(15987..16199)
                     /locus_tag="ACGI3L_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9198184.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(16520..19306)
                     /locus_tag="ACGI3L_002485"
     CDS             complement(16520..19306)
                     /locus_tag="ACGI3L_002485"
                     /inference="COORDINATES: protein motif:HMM:NF012772.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9198185.1"
                     /translation="MRVGYCDDYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKG
                     SWEECLDRLEKGEIDLLGPLQKNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDI
                     SSFKGMRVAVLRGNFHNTAFEKYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGS
                     IINAKGMKIVSKFSVEPFYFATAKDKPNLVKELDYALKELKINDMYYELELYKKYFKR
                     EVNNSIAFTRQEMNFIKANPKLTMVYDSEWSPVEYYDEESNSFKGISSDLMSIISKKC
                     GIKFEYIKTKNYNESLDYIKSGKATMLCGSINENDKVKRFNMKLTNPYINIPMIMVGK
                     LDTNLNNDLNIALTSSYKSIDSYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSS
                     YQFDELLREGKSENLSVISVLDTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDC
                     IYSNTIDKPYKVPFGVIFKEYSIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTD
                     PLTGADSIDKFKINSNKLFAKNNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISN
                     TIASELKEDEIFARVSADHFVLLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLIL
                     DCGIYKISKSDNDINTIMDRANTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMV
                     DALNNGEFIVYFQPKYSLSDYQIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNI
                     DFYVFEEVCKKIREWMDEGQKVVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIE
                     LELTETAVLDNIEGLLDTMNNLKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAF
                     FTEKDESNNEKIVISNVIKMAKELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKP
                     MPVKEFEKIAFKKE"
     gene            complement(19743..20351)
                     /locus_tag="ACGI3L_002486"
     CDS             complement(19743..20351)
                     /locus_tag="ACGI3L_002486"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HFG9198186.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(20611..21156)
                     /locus_tag="ACGI3L_002487"
     CDS             complement(20611..21156)
                     /locus_tag="ACGI3L_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HFG9198187.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(21274..23097)
                     /locus_tag="ACGI3L_002488"
     CDS             complement(21274..23097)
                     /locus_tag="ACGI3L_002488"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198188.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRILNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSILLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(23110..24885)
                     /locus_tag="ACGI3L_002489"
     CDS             complement(23110..24885)
                     /locus_tag="ACGI3L_002489"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198189.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         8249 a         4342 c         2447 g         9992 t
ORIGIN      
        1 actaaaaatt ctataaaaaa ataagataca tacctataaa ataccttcct atagatacat
       61 atcttaccta tataaaaact tattctatat aaaaacgcca taaaaaatct tttgcttctt
      121 ctgcataatc tatatttata cgtttactag tttttatatc taactcatct ttactaaata
      181 ctttttttcc tttatcatca taataaaaat cacttatata taattcttca cccattatac
      241 tcttactatt tagacttcta tctattttta aagctttgca aagttttcct ggtccgttag
      301 taatattttt tacttgatat ttactcaact cagtgtaagc tttgttgtat ctattcatag
      361 atatctcatc taaagaagtt ataggctcta cccctcttat taatacacac tctggcacat
      421 tttctatatt tgcagataaa ttcaagcaat tatacatacc ataaattaaa taaacatata
      481 tatgtccacc atctaaatat aatggcttag ttctatctgt ctttttattg ccatatacat
      541 gtgctccttt atcatttaca cccatgtatg cttctgtctc tatgattttg gtaacaatta
      601 ctttattttc atatttcctt attagatatt tacctaatat tgatttggct aaatcaattc
      661 cattttttct aaaaaaatcc ttttccaaaa tttcacctca taaaatttat ttaaaacgca
      721 tcaaatacaa ctaaagtaat aaataaaatt aactcttatt aatgtgatat atataaacaa
      781 taaatttaga catttattat ttatatatat caaaaaattc tatctcaaac ttttcaatat
      841 tatcattgta atttgaatta tcatatactt cttcaacaac ctctttaatt gggaatataa
      901 cttttacatt agttccttct cctaccttac tatctatgta aatcttccca ttttgaattt
      961 caatcaatga ttttgtaagg cataaaccta taccacttcc aaattcattt gatataccac
     1021 tgttttcaat ttgtttaaat cgattaaata tatcctttaa tttttctttg tctatgccca
     1081 ctccagtatc ttttataatt atctctactg tttcgtcttt tttatatata cctacaagga
     1141 tttctcctcc ttctaaagta aattttatag catttgataa tatatttagt attattcttt
     1201 ctatcgattc tgggtcaagc cctaccataa cagtttcttc atctgtatca aaaattaaat
     1261 ctattccttt agacttagca taactactaa tagatgtaac tattctttct gttatgtcaa
     1321 taatatcaaa attaactgct ttaatcttat atatgtctga cttaacttga gaaatattta
     1381 ttatattatc tattaatctc aataatctaa acatattttg tttagttatt tttatatgtt
     1441 cttttagtat atcctgaaaa tcaattattt ttcctttttt ataaaggttt tcaataagtt
     1501 gaactgaact atatatatta tttaaaggtg tcttaagttc atgagatata ttagcataaa
     1561 actccatctt catttggtca tactgtcttt gttttattaa tgctttttta agtctttcag
     1621 actctctttg cacacttaaa tctttaataa ttctcactct acttcttttc tgtccaaagt
     1681 ataatgttct tgatatcatt tttacttctt taatgtgatt attttcattt actatatgga
     1741 tactcttctc tctttctcct atatttaaat tgtttatgta tttttttact aatatatttc
     1801 tatatttttg tgttgtaact cctaatacat cactagaaat tccgaacaac tctctaaagg
     1861 ctctatttgt atatagtact cttgatgtac ttaaatcctc aagaaaaata gcctctggta
     1921 taacatccag taatttttca tatattattt tttgttcatt tactgttcta agaatattta
     1981 tctctttagt tatatctcta aatgtaagca atttaaagag tttattatct gaccaatagt
     2041 ctccaactct aacttcttca acatgttctt caccttctga gtcagacatc acaaaattaa
     2101 ctatacagtt tgctgtgtca ttgtaactta ctatttcagc tttcttttct tgtgttagat
     2161 ttaatctttt aaattcccta ttgtcaaaga aatctatgtt aaaagtttca aaatattgtt
     2221 ctaatgtcat atcgactaaa tcacttgaaa cacatttaaa actcttttca tattttttat
     2281 ttatacttat taccttattc ttctttatgc caccttcagc acttcttaca agtataggag
     2341 atggaatatt tagtataatg ttttcatagt ctttatttat atttcttatt tcttcatcta
     2401 ttttgatttc atttgtaata tcatttaaac ttattaagta attgctttcg tctttattat
     2461 tacttaaact taacaaataa attttatcat ttaactctac cagtttatca attatactta
     2521 tatcgttatc aaatttcttc aatttttcag caactttttc atcttccttt ataaaagtta
     2581 atattttata ataattattc atatcctttg aaaattcatc tttaaattta ttatttgtgt
     2641 aacttatatt aaaatcatag tctgttacta tccatacatt tggtattgta tccagagctt
     2701 gtctaagtaa ttcttttctc tggtctatgt agttttttaa tgttctttgt ataatcatat
     2761 ccttttctat tgctaaattt atctttccta attgctctga ctttttactt aattttttat
     2821 tgattgaatc aagttcataa tatggataca ctactctatt attaagactg tatacatata
     2881 cataataagt atggttacat aatagtaaat atattactcc tattaatcta tctgaatcta
     2941 ctatattaat cttagaaatt gctacaaaac atataatagt tgtaaaaaaa acaaaatatg
     3001 ttaaatcttt tattaactta tagtgctcaa tgttactatc aagtttattc aacaaatata
     3061 gtaaattaaa catagatata caaatattaa ttaatataat aatcatattc cagttaatat
     3121 cactaaaaat atttcttata aagtaatcta atatcacaaa agcactataa aaaattagta
     3181 ttgggcttat tcttagtttt tttactttag aaatggttaa gtatataaaa gtagacatat
     3241 taattatgct taagttaagc aatacaattt ggaatttttg aatttttaaa tttactactc
     3301 ctaaaatact tacaaaaact aatacaagac accctacttt caatatattt ataaattcat
     3361 ctgttttaaa gctacttata taaactatag aatatccaaa tatccaaagt aaaattattc
     3421 tatacatatt tatagaaact gtatacaaat ttatatttaa aagtgcaata accaaaaata
     3481 acccattagc tagtatatag accttattct tacttaaagt tcctttagat tccatattcc
     3541 ccaccacttc ttcattttta tatagtttta cctataaata tgttaccaca attcttccaa
     3601 aaaatttgtc actttctagt tataaaaaaa aatgagtaaa tatttttaat tttactcatt
     3661 ttgtagattt tgtatattca gtttaaaaag ctggaactat acttccttta tattcatctt
     3721 gtataaattt tttaacttct ttactattca tagcctctga taaagcctta atcttatcac
     3781 tatctttatt attttctcta caagctatta tatttacata tggagaatca cttgattcta
     3841 ttactattgc atccttagta ggatttaagt tagctgttaa agcataatta gaatttatta
     3901 ctgctccgtc aacatctttt aatactgttg gtaattgctc tgcattcatt tcttttatta
     3961 ctatattttt aggattttta gttatatctt ttttagttat aagctctcca tcttttactt
     4021 ctatcaattt attttttgct aataatttaa gtgctctagc tccattagtt gcatcatttg
     4081 gcacagctat aacagctcca tcttttaatt catctaatga cttaactttt tctgaataga
     4141 atcccattgg ctctatatga actttagatg tataagtaag tttatatcct ttctccttca
     4201 cagtttcctc taaaaatgga atatgttgaa agaagttagc atccaaagac ccttcatcta
     4261 aagctgtatt tggaagtaca taatcatcaa atatttttac ttctaaatca tatccttttt
     4321 cttttaacaa aggttttgca acttccaata tctttgcatg tggatttgat gaagctccta
     4381 ctagtatttt tttatcctct ttgtttgaac aacctactgc tgatattgct attgctgaca
     4441 ccaatgctac tgataataat ttctttaatt tcatttttac tccccctctt taaaatgttt
     4501 ataattaatt tattttagtt tcttataagc cagatttcct actccctgga ttatctgaac
     4561 taatattata agtgctatta cagtatatac cattactgct gtatcaaatc tttgatatcc
     4621 ataaataagt gctatattac ctaatcctcc agctcctact gcacctgcca tagctgtata
     4681 accaagtata gatattattg ataatgtaat tccagatact attgaaggca tagcttcctt
     4741 tatcataact ttaaatacta tttgtctttt tgtagctcca aaagattttg ctgcttctat
     4801 caatccttta tcaacttcat ttaatgagct ttctataatt ctagcgataa acggtgctgc
     4861 cccaatagtt attggcacta ttgcagcagt ttcccctata cttgttccaa cgattaatct
     4921 agttattgga atcattgcaa ctataagtat cataaatggg aaacttctaa atatatttac
     4981 tataaatcct aatgcactat ttattgtgct atttggtttt aatccatctg gttttgtaac
     5041 tactaatatg attgctaata taaatcctaa tattgttgcc actatagttg gtactataac
     5101 catatacaaa gtttgtaaca atgcatttgg aaatagtgtt gttaaaaagt caattaaact
     5161 attcatttat catttcctcc catcttatgc ccttactagt tagatattgt tttacttgct
     5221 ctccactttt atctgaaatg tttataataa gtgaacctaa aatatcatct ttaaattgtt
     5281 ctaatttccc aaatattata gacacatcta tatttagttc tcttgccata gtcgtaataa
     5341 tagcttcatt agaaatatct ttagggaata gtatctttat atttgttcct tttggcaata
     5401 ttatactttc ttcacctatt aattttctaa gtcctttagt atttcttaag aatatttctt
     5461 ctgtatctcc tacctctaat acttctccat tttccattat tgctactctt ccacaaatct
     5521 gctttataac ttccatttga tgagttacaa ctattattgt tattcccaat tttttattta
     5581 tatcttcaag caatgaaaga attgactttg tagtatttgg gtctaatgct gaagtcgctt
     5641 catcacaaag aagtacttgt ggatttagtg ctaaagctct agcaattgca accctttgtt
     5701 tttgtccgcc acttagattt ctgggtttat catttttctt ttcagatatt ccaactactt
     5761 ctaataactc taaaactctt tttttaattt ctgcctttga gtatccaaaa cattctaatg
     5821 gcaatgctac attatcaaat acagtttttc tttcaagcaa tgaaaagtgt tgaaaaatca
     5881 ttcctaactc ttttcttaaa tctctcattt gcttttcatt caatgacttt acttctttat
     5941 cagaaacaag tacactgcct tcttggtatt cttctaatcc gtttatacat ctcagtagtg
     6001 ttgatttccc tgcaccacta tgacctatta ttccaaaaat ttctccagat tctatttcaa
     6061 tacttacatc tttaagcact tgaatctttc cataatactt attaacattt tttatgctaa
     6121 tcataaaatt tcctcccata tattctgctc agtttttatg tttatcctct cttatgtatt
     6181 acaacaaaat aaaagcccga gtataaactc aggcttagaa agctatttat actcatctat
     6241 caactatatt agttgcagga tttagcacca atgtatataa aatatactgg ttgccgggtt
     6301 tcaaagggcc agtccctcca ccactcttga taagacgtta tttaatttaa ttctattatc
     6361 atttgttgct atgttatata tgatatattc attaatagta tttgtcaata aatttattta
     6421 aattttttat tttttattat cgttaattaa ctatttttaa ttagttttct agctcctaac
     6481 actttatatt ttaatgtcta tataactata gaacatcatt ataagaaata aattaaataa
     6541 catcaatcta tctaaatcat ctgtaaagta aattaagaaa attaacattt tatccaaact
     6601 ctatcctact attaaataaa ataatttaaa tacaatgatg attatatagc tctagtactt
     6661 tagactttat caaatgttta agttctatag gttctattat tgtagcattt ttcccaaaag
     6721 ttaaaaaata ttcagccacc cagttaagtg tagattttgg tatatacata tctatgtatc
     6781 cacctttaga caagattttc aaccctcttg ccaacaaaaa ttctgtttca caacgtttta
     6841 ctccctcatc tgtcaaatta attttaatat gataatctgt acctacttcc atattcttaa
     6901 gataatcatg tatagaagat aaaaccttat atttcttact tgataagttt tctatactca
     6961 aaatcttcac aattctgtct acacgaaatt ccttaataga ttctgatttt atacagtaag
     7021 ctggacaata ccaaagtcca ttcatggcat acaaaccaat aggaacaatg gtacgtacac
     7081 tatttttttg ctttgatgaa tattcaattt taattgtaaa ttcattcatt actatattaa
     7141 acaattcttt caataatggt gttgaacagt gcctatctgg tgtccaaaaa acaaatttac
     7201 gccttatatt ctcaatatta tattgaatat catttggtat acaatttaaa aattttttta
     7261 aaacagaaat agtttcttgc tcaaatggca aatcattata atattctagt gactgatatg
     7321 caaagaatat agattttacc tcactttctg aaaatgcaat cggtggaagt atacgctctt
     7381 taagtacatg atatccacca gccgctccaa cttttgaata taatggaaat ccaatactct
     7441 ccagcacctg taaatctctt agtatagtac gttttgatac agaaaattct tctgctaatt
     7501 ctcctgctgt aaaacttctt tttgcattta ttgttatcat cagttcaatt aaacgctcag
     7561 ctcttgacat atttatactc ctaatttaaa tatagtgaca ataattgtca ctattatatg
     7621 ataagatatt cttgcatcta aagcaataat aatagtaaag aaagaaggga ttgatacttt
     7681 atggaaaatg atactattaa ggctgatgat attctcaatt attgtctatc aaacttagat
     7741 gatgttgtac taatggatag ttggggggaa cgagcaattt actacaatcc taatggtgtt
     7801 ttaaagcgag gggtatatgt tcttaccatt aaggaaaaag acagtaataa tgataaaggt
     7861 tcgttagtta gtcgtccaaa tgtataccgt gtgaatatag gattaaaaaa agaaactttt
     7921 attgaaatgt ttggatatat tccaaagcgt ccaggtgtag gtcaaatagt tgatatggat
     7981 tttgatttta caaaattgga cacaatcatg ccacatccta tctactcatg gatgggatgg
     8041 atatgtgtcc taagccctac tgaaaagaca tttgagaact ttaaaacttt aataggagaa
     8101 tcttacaatt ttgcaaaaca aaaatttaaa aagagaaaaa acaagtaaaa acgtgtgaaa
     8161 ataacctcta aataaattat aataaaaata ttaaggttac aagataaaaa ttaatatctt
     8221 aataacatgc aaaaaagcga agccaaaaaa tgtattattt ataaggcttc gctatatctc
     8281 aaataattta tttcaaattt caaaactatt tattctatta tttcttatta tttcctgtta
     8341 ttcctaatct atcattcata tcttttatca tttttctaaa accactacct atatcatttc
     8401 caacatcttc agttccatga actaatttta taaagtcatt ttgacctttt ttcatatctt
     8461 catcagatac cttatctaat ttttctattc tcttatctat atcttttact aatctttccc
     8521 cttcagcgat taggtcatca ttcattttct ttaactctgt atcttctgtt ttaccatctt
     8581 ttttaagaga tgttacaaat gattgtattt tatctctact atctttatat gcagccttta
     8641 catcacttag atatttttca tttcctggat attctttatc tttaaactga ttatttatac
     8701 tttctggagt atcataaata gaatatctat ttagacctgc tatataatca ttatagcttg
     8761 ttgaataata attcatatat ccttcattat tatttacaga ttcattagga ttttttcctg
     8821 tattttcact tggtttttca ttatttttag tacatgcagt tatacctata gctaatacta
     8881 gtgctaatcc tacaaataaa gttcttttta atttcatttt tattaccctc ctagatgttt
     8941 tatactataa aaaattttaa taattttctt tcttaattta gtatttctat atttttatat
     9001 tttatttact aaaattaaac aagttataat ttattttttt ggaaatcata atgaataaat
     9061 aattaaataa aaaaattata attttatcat tgatattgat tatcattcat agtataatct
     9121 aattacttga tattaatttt catttgaagg aggttatctt ttatgtcttg ttgtaattca
     9181 caattttgtt gtaaaaataa aattgaatca tcatatataa aatggctttt agaagtttta
     9241 ggtccagtct ttttaggctc taaacctgct gaaataataa atatttcgtt tactgatgta
     9301 aatagagagg aaaaaattaa tgatatttat aaatatctat ataagtgtaa gaaaatagat
     9361 tttatagtta ttgataaaga aaaaaaggga ttaaaaatct tatttgtaaa taaaaaagca
     9421 ttatcagaaa aattaaaatg taaaaaaaca gtaaactttt taaagttttt aggatacaaa
     9481 caaaatacga atgttaatgc ttatttagag catttagtag ataaacttaa gagtgatgtt
     9541 tttcctgatg aaataggtat ttttttagga tatcctctta aagatgtgat tggatttatg
     9601 ggatatagta attatgaagt ttctatgatt aaatattgga aagtttatgg tgacacaaaa
     9661 caatccgagg acacatattc gaagttttta cttcaccgta agaaaatgag aaaattacta
     9721 gactacataa gtgtagataa aatagtaagc tgtttttaat tgtgtttttg tataataata
     9781 aaaatacacc ctcttttacc atacagtttc cataataaat aagggtgtat tttccacttt
     9841 aatattttaa agtattctaa ttttgattgt acaacatatc tttaatattt attttctttt
     9901 gttgcattcc attagacatc aaaaattcct gtgtatcttc taattctttt atatccttgt
     9961 ccgttatttt agaactaaag tcataccaag aatacatttc ttttgtttca tctaaagata
    10021 aaccaacttc tttagataca acatccatca cttcatcctt gttttcattc atatatttta
    10081 aagtttcttc atgaaccttc ataaatcttt ttactaattc aggatatttt tcagcaaagt
    10141 catcacttac agcagtaact attattccac ttactaatcc ttctccattt acaatcattt
    10201 tggcacctga atttatcgtt ttcaatgcca ctggacctgc aagcattgct acatcagcac
    10261 ttttactttc taatgcagaa gcagcactag gaatatccat atttacatat tcaacatcat
    10321 ctatagtata gccttcttta gcaagtgcag caatcaacag ttgatgaagt atagtccctt
    10381 ttggacctac aattttttta ccttttaagt cttttataga tttaatatta tcattattag
    10441 ttataagcat atatcctttt ggtgaacggc tataaatatt cgtaatttta agaccaacac
    10501 catttgatgc agctattatt gcagacgttc ctcctaatgc atgtaaaaag tctagctcac
    10561 ctgctgctaa tgcttgagtt tgctctggtc ctgttgtcaa ttcatggaaa ttgactttta
    10621 tattgtcctt tttaaattcc tttccaaata aatcatcctt tttttctaat atactaggaa
    10681 cattaagtgg tgattttaca taagttaaat ttatttcctt aggtaaacta gcctcttttt
    10741 ttgcaggttc atctttctta tcatttgttg ttgaacatcc tacagtccca accaacacca
    10801 ttattaaaga tgtcattact gctaaaatct ttttgtttct tttaatcaat taaaactccc
    10861 ccaattccct taatatttct tttttcaagt ttatataata gtttttagtt aaatctctat
    10921 tatattcatc ttcgacacta aattgtttaa tccttttatt tttactaaaa acaattattt
    10981 tctttgctat ttccatagct tcttcaatat tgtgagttac aaatactaca ccttttttag
    11041 tatttttatg gatatttaca acttcttttt gcatttttct tcttgtgaag taatctagtg
    11101 ctgcaaatgg ttcgtccatc agcaaaatat cgggattgaa ggaaagtgct cttgctatac
    11161 ttactctgtg agccattcct cctgataatt catttggata tgagttttta aacttttcaa
    11221 gcttcatcat ttttaaatac ttgtctaaat caactttatt tctattatct ttttcagtat
    11281 gtaaaagtat attttcactt acattcagcc atggcataag tctactttct tgaaatacca
    11341 ttcctacttt tggagtacac tttttatcat tattaaaaaa atatacgttt ccactagtag
    11401 cattttcaag ccctgctaaa attctaagta gcgttgtttt cccacatcca ctttcaccta
    11461 atataacagt tatctcttca ctagatatat ttaaagatat attatcaaga actaaatgct
    11521 ctttattatc aactaaatat ttcttatata tattctctag caaaaatcca cttctaacca
    11581 tttaaatcaa cctgcttccc tttgctaaat tttgttatta tctttgaaaa tagataatct
    11641 gaaagtatac ctaaaaatcc aataacaaaa attcctacca atacaacatc agttctagac
    11701 atatcttttc catcagaaat caaatatcct agtcctgaag aagctgcaat aagctctgct
    11761 ccaattatag ccctaaaact atacccaagc cctaaactaa gtccaacaac aatatccagc
    11821 atagaattag ggattattat tttataaaaa attctctttt tagataaatt aaaagattta
    11881 cctacttcta ttaatttatt gtcacaattt tttatacctt tcaatgtatt taaaaatatt
    11941 ggaaaaaagg atgccaaaat aataattata attttagatt cttcacctat accaaaccat
    12001 aaaataagca ttggcaccaa agctagtgga ggtgtacttc gcataaattc aaatagtggt
    12061 ttgaaatatt catacatttt tttatttgct ccaaataaaa ctccaagtgg tatagccatc
    12121 aatgaactta ttaaaaaacc tattaatatc cttcttacac tggcataaac atttaagaaa
    12181 atagaaccgt catatatcat ttttataaaa gtatctaaga ctatttcagg aggaggcaga
    12241 atatagctac tccatatacc caaaacacat actatcttcc ataaaattaa aattattaaa
    12301 aaaatataat atcctttaag ccttttatga attttctcaa acatataaaa ctccttttaa
    12361 catatctatc cctgctaccc tttttatttt ttaatatctt aaataataat taagctatat
    12421 cataagattt aatctatgcc aagtcttaat ccacctgaac tcattctatc agaaggtgta
    12481 gaatctgttt ttaagccaga caatctttca gatggttgta taatgactat ttgtccaggt
    12541 tcaacaaatt ccatatgata agattctcct gaagtctgac caataaaagt cttccatgat
    12601 agttttgata ctttaggata tggttctctt ccagtccaag ctactaatgc atctgggtca
    12661 acacaacaag gtccttcaag aattagagga ttaccatctg ttattatagc aacatcttga
    12721 ttttgacctg ttttatttac taaatgtgta gtaaaaagac ctttttgaga tattacccct
    12781 gaaccaatca attttacact gtaatttaat tgttcagaaa atgccaataa gttttcactc
    12841 tcaacataaa tggaatcacc tgggtcaatt gatattacat ctacatggta agcattttga
    12901 gctaggtaaa tttcaccttc accttcaacc accattattg gcatttgttc tcctgtcaat
    12961 gacctctgaa catgacctaa taatgctctt cccaatccac cgccattact tggacctaac
    13021 agcaattttt caaaattaaa atttccttta aaggctacca tagcaccttt ttttgcaaaa
    13081 aatttaccac ttccccttgc tatacacata agctcgtttg taacatcaaa tttaaacata
    13141 atattcactt atattgctta atttagcaat aatccctcct aatcatatat ttatatataa
    13201 ttatacagta aaattacagc atagtctaac ctacttcaaa tatgaaattt gttatttata
    13261 caaaaaataa gaacctgata ataaagcaat ttaacttttt atcaggctct tatcctattt
    13321 atctcttagc gctatgacaa ctcttactac ttgagcatcc agaacaacca catccacaac
    13381 tgctaccatt cttttttgaa tttttaacca tatacattac agctagtgcc attaatacta
    13441 ctacaatagc tgctataata aatgtagcca tattcatcac tccttattta tatgaattaa
    13501 tttttcatat aacttaattt acccattttt tcttttttca tatttttatt tgaataagtt
    13561 aaaactacaa agactactgc tactgctata aatatagata ttattgcccc agcaatactt
    13621 cctccagtac ctaaaactaa acttccaact tgatttataa gaagagcaat tatatacgct
    13681 gttaaagttt ggaatcctaa tgtaatccat gtccatttcc atgaacccat ttctcttttt
    13741 atggctccaa tagctgcaaa acaaggtgca caaagcatat taaatgccat aaatgcaaac
    13801 gcactagcta ctgtaaacat acttgcaact gaagcaagaa gtgttgggtc ttgctctgtt
    13861 gcatctgata taccaaataa aactccaaat gttccaacta cattttcctt agctactaga
    13921 cctgtaactg ttgctactga tgattgccaa tttccaaatc caagaggagc aaatattggt
    13981 gcaactatat ttcctaagct agctaatata ctatctccag catctaccat ttgtaatgac
    14041 caattaaatg attgtaagaa ccagattact ccacaagcaa caaatataat tgttcctgct
    14101 ttgattataa atgcttttcc tctatcccac atatgtatta aaacaccttt tgcacttgga
    14161 atatgatatt gaggtaattc cataacaaat ggagatggtt ctcctgcaaa taaactagtt
    14221 ttctttaata taattccaca aatgattatc attgcaatac ctaagaaata cattgatgga
    14281 gctacccatg aagcacctcc aaataatgcc cctgcaaata atgctattat tggaatctta
    14341 gctccacatg gaatgaatgt agttaacata atagtcattt ttctatctct atcattctct
    14401 atagtacgag ttgacataac tcctggaact ccacaacctg aacttataag cattggtata
    14461 aatgattttc ctgaaagacc aaacttacgg aaaattctat ccattataaa agctacacgt
    14521 gacatgtacc cacaatcttc taatattgat aataataaga ataaaagcat gatttgtggt
    14581 acaaatccta gtactgctcc aactccacca attagaccat caactacaag tccttgtaac
    14641 cactctgcta catttaaaga agctagaaaa ttacttacat tgccttgaat aatttctcca
    14701 aacagtacat catttgtcca atcagttgct atagtaccca atgaacttac tgctatatag
    14761 taaactcccc acattataag tgcaaaaata ggtaatgcta gtatacgatt tgttacaatc
    14821 ttatctatct tatctgatac agtttcctta ccttttcgat tcttctttat tatacttgaa
    14881 attattgaac taataaattc ataacgattg gctgttatta tactttcact atcatcatcc
    14941 aattcatctt cacaatttct agttatttct tcaatactat tcaatattgt tttagaaata
    15001 tcaagttttt gtataacatt ttcatctctc tcaaatagct ttatagctaa ccagcgtgtt
    15061 tctacatcta tatatggagt cttttcttct attatttttt caattttttc tattgcatcc
    15121 ttactttcat caacaaaggg taatttgaaa tttaatttat tgttactact tgcaagttca
    15181 actgcctttt cagcagcctc cataattcct tgacctttaa ctgctgttac ttctaccact
    15241 gggcaaccta taacttcaga tagttcttta atatttatct tatcaccatt cttatttaca
    15301 atatccatca tattaagagc tataacggtc ggtataccta gctctaaaac ttgagttgta
    15361 agatataaat ttctctctat atttgatgca tctacaatat ttattactgc atccggctta
    15421 tcatctagca taaaattacg tgtaactact tcttctaatg tatatggaga taaagaataa
    15481 atacctggta aatctactat ttccacatct ttatttcctt ttaattttcc accttttttt
    15541 tcgactgtta ctcctggcca gttaccaaca tattgtgatg agcctgtaag cccattgaac
    15601 attgttgtct taccacagtt aggatttcct atgagaccta tttttattga catttccatt
    15661 ccctccatta ttatttaaat acatcactgt ttgtgataca gaaaatcatt ctcattatat
    15721 aattacatta accctactct aattaatctt tattattcca caataatttt ttctgcatct
    15781 gacttacgaa ttgatagttc ataatctctg actgttacct caattgggtc accaagagga
    15841 gctacttttc ttataaatat attaacacct cttgtaatcc ccatatccat tatacgtctt
    15901 cgtgtagctc cttctccctc taactttttg acttttacag tctctccaca cttaatatcc
    15961 ttcagtctgt tcatgtcatt acctccctat attattattc tacttgccat ttttttatct
    16021 aatgcaactc tagtatcttt tacgtctatt attaagttac catctatctt agaaactatt
    16081 ttaacatttg tacccactac aaaacctata ctatttaaaa aagtcctcgt cttatcactt
    16141 cccgaaattt tctttataac tacttcttca cctgtatttg ataatatcaa tggcatcata
    16201 taatatccct cctcttaaag taatttaaat ctacaagcaa tcgttatctt atatataaat
    16261 tacaatacct taaatcttaa tctattaaaa taacatccta ttttttcctt ctttttacaa
    16321 ttcctaattt tgatttaagt ctatcacaat agtatatttt ttgcaagtga ttattgtatt
    16381 cttttgattt tttttctcat ttgatttatt ttattaataa aatcgtaaaa attaatacaa
    16441 aaataaagat gctctaaaat agtatactca actaatatta aagcaccttt attatatatg
    16501 tcattattta cacattgctt tattcttttt taaaagcgat tttttcaaac tcttttacag
    16561 gcattggctt agaaaacaaa tatccttgta ccatatcaca cccaatttgc tttagaaatt
    16621 ctacttgcga aatagtctct acaccttctg atattacttt cattttcagt tcctttgcca
    16681 ttttaatgac attagatata acaatttttt cattattact ctcatctttt tctgtaaaaa
    16741 atgctctatc tagttttaat atgtcaacag gcaattcttt taaaagatta agagaggaat
    16801 atcctgtacc aaaatcgtcc atagagatta caaatccctt ttctttcaaa ttgttcattg
    16861 tatcaagtaa tccttctata ttatctaata ctgctgtttc tgttagctct aattctataa
    16921 gtcttgtcgg aattttgtat ttatctacaa ttaatttaaa ctcctctata aaattactat
    16981 ttacaaaatg cattcgagac aagtttacag atataggtac tactttttgt ccttcatcca
    17041 tccattctct aatcttttta cacacttcct caaatacata gaaatcaata tttacaataa
    17101 aaccattcct ctcaaataca ggaataaatt ctattggtgg tattagacct ttttgtggat
    17161 tatcccaacg aacaagagcc tctgccccta taatttgata atctgaaagg ctatatttag
    17221 gttgaaaata aacaataaat tctccattat taagagcatc taccattgaa ttttcaattt
    17281 ctttctcttt taatattttt ttgtgcattt ccttatcgta aaaagcaaat gaatttttat
    17341 gaccaccttt tatagttttt cttgcagtat tagctctatc cataatagta tttatgtcat
    17401 tatcactttt acttatttta tatataccac aatctaaaat caatttataa tagtttattt
    17461 taggattact aagtatttga accttattgt aaatattgtt taaccttgtt ttaatatcat
    17521 catctgtctt atacttaata agaagaacaa aatggtcagc agaaactctt gcaaaaattt
    17581 catcttcctt taattcactt gcaatagtat ttgatatatg tatcaaagta tcatttccca
    17641 tatcatatcc aaacatatca tttatatatt taaatttgtc aacatctata taaaacaacg
    17701 catattcttc tggattattc ttagcaaaca gtttattaga atttatttta aatttatcta
    17761 tactatctgc tcctgtcaat gggtctgtat atgctatctt ccttagataa tcctctttct
    17821 tctttttatt ataaattata tatttaatag caattaagaa taaaatacat acaaaagaaa
    17881 taatttgtat tgaatattct ttaaaaatca caccaaatgg tactttataa ggtttgtcaa
    17941 tagtattaga atatatacaa tcacttaatt cttcttcagt aattttgtct attgatttat
    18001 ttaaaataga cactaatata gggtcagttt tatttgatac ccctatacgc atcccatagc
    18061 ttgtatctaa aacagatata acagataaat tctcactctt tccttctctt aaaagttcat
    18121 caaactgata agaactaagt atcattaagt ttgctttacc ttcatttata gcgtttagac
    18181 aactttctac actcttataa gatgttgtct tagcattttc aaaactcttt tctatataag
    18241 aatcaataga cttataacta ctagttaaag caatatttaa atcattattg agattggtat
    18301 ccaattttcc taccataatc attggaatat ttatgtatgg atttgtcaat ttcatattaa
    18361 atcgttttac cttatcattt tcattgattg agccacatag catagttgcc ttaccacttt
    18421 ttatgtaatc aagactctca ttataatttt ttgttttaat atattcaaat tttataccac
    18481 atttttttga tataattgac attaaatcgg aacttatacc tttaaatgaa ttgctttctt
    18541 catcataata ctctacagga gaccactctg aatcatatac catagtaagt tttgggtttg
    18601 ctttaataaa attcatttct tgccgagtaa atgctatgga attattgacc tctcttttga
    18661 aatatttttt atataattcc aactcataat acatatcatt tatttttaat tcttttaaag
    18721 cataatctaa ttcttttact aaattaggtt tatcttttgc agtagcaaaa taaaaaggtt
    18781 ctactgaaaa tttgctaact attttcattc ctttagcatt tataatactt ccacaaacaa
    18841 atgcatctgc ctttttttca ttgacggact caattaattc atcaatagaa ttacagtata
    18901 tatattcaac tgaaaaatta ttttcttctc tatacttctc aaatgcagta ttatgaaagt
    18961 ttcctctaag tacagctact ctcattccct taaaggaact tatatcttca taaaacatat
    19021 tattgttact atcctttgta tatagtgcac tatattcata tcctgaactt agtttaggaa
    19081 aattaaatag tttatttctt tcatcattct tctgtaaagg tccgagtaag tctatttcac
    19141 ccttttctag tctgtctaaa cattcttccc aagacccttt tacaaattca tattcccatc
    19201 ttgtatattt tgagatttct cttagataat cataaccata tcctgtataa gaatgctctt
    19261 ttgatgagga tattattccg tagtcatcac aatatccaac tcttattttt ttgaattttc
    19321 agactcatca gcaaagcata gtatattgtt aaaacatgat ataataagta aaaatatcaa
    19381 agaaagtatc aagaagtgct ttttaaatgc tttcatattt aaaaacctcc aatttgccaa
    19441 cttactttaa cttatttcgt tttctagttg taactacttt tattgtaatg gtaaatatat
    19501 caaattgcaa tattctcata taatattctt attcaactat aatgaattta ttattatcta
    19561 tttaaataca ctatctaata ttagtttctt ataagtcata aaagcacaac taacactata
    19621 attctagtga ttaattttat ttcaaaaaat ataataacac tactaatatt ttaaatatca
    19681 atagtgtcat aaaaactttt cagattaatt aaatctttct atatatttta taataatcta
    19741 aatcatgcta aatatttaga cagaaaactt ttttctttaa tagtaaatac ttttgtttga
    19801 atatcagaat aattatttga atatctatct ataaaaccat gatttgcatc taaaatctca
    19861 atttggatat tttgtttcct agaaagttgg taagaaatag aatcaacatc aaatgaatcg
    19921 tgctttgcaa atactaataa ggtaggacat tttggaatta catccatgta atctctaatc
    19981 cgagagccat aacaacaaat tatgccatca caaaaagaat cttcactgca tctccatgca
    20041 atagttgctc ccacgctata cccagcaaca aatacatatt tatactctga ttttaaatca
    20101 tttataagct tttcaacttt tttataaata tcaaaaccaa cattatttat aaaaaaatca
    20161 tatgcctctt ggacttttga atatggaaaa actctttttt ctcccagaag ttcaggacaa
    20221 aatacatcat atccatattt ataatacttt tgacaaacat cttctataaa gctattaatc
    20281 ccatagattt catgcaaaac aacaatagct acatcacttt tatgtatata ctttatcaga
    20341 ttatccacca cctttacaaa acagcaaatt ttttatactt agtttaatat attcttcttt
    20401 acatgtcaat ttacttttct aaaatcaaat ttatttttgg attaatcatt tatttttaaa
    20461 agttgtgcat tattactatt aaattattct ctattattaa aaatataatc gttagaaata
    20521 aaaaataaag tacaaataat taaaaaatat ctcactcata actttaaaaa ttataagtga
    20581 gatactccta aaatctactt tatattaaat ttattttcca aaatatctat ttaataatcc
    20641 taaaaatgct ttaccatgtc tagcttcatc tttacacatt tcatgtactg tatcatgtat
    20701 agcatctaat cctaattctt ttgctttctt agctaatttt aattttccat cagttgcacc
    20761 atactcagca tcaactctaa ctcttaagtt ttcttttgta tctgcaacta caacttctcc
    20821 aagaagttct gcaaatttag cagcatgttc agcttcttca agagctattc tcttataagc
    20881 ttctcctact tctggataac cttctctatc agcttgtcta ctcattgcta aatacattcc
    20941 tacttctgta cactcaccaa caaagttagc tcttaatcct tcgattattt cttcatctac
    21001 accttgagct actcctattc tgtgctcatc agcccaattt ttttcgcctt tcatttcttc
    21061 aaatttatca gctccaactt tacatactgg acattgtgct ggtgcagcat ctccttcatg
    21121 tatatatcca catactgtac aaacaaattt cttcataatt actttcctcc taaattttat
    21181 atatcaaatt aaatttttta tttattaagt tagtctatat atacccgcac catatacctt
    21241 taaacaattt ttttaaaagt tttttctaaa tacttatttt ccctgtgtca ataatatgtt
    21301 tctataataa tgtcccttta attttatcaa ttctttatga tttcctgatt ccacaattct
    21361 accattttct aaaactatta tattatcaca atttgatatg gtacttaatc tatgagctat
    21421 aattatactt gtctttccat aagttaaatt atttattgct tcttgaattt tagcttctgt
    21481 tgctatatct atgttacttg tagcctcatc caaaataagt attggagcat tttttaatac
    21541 tgctctagca atacttatta attgtttttg accttcactt aaatcttcac ccctatccga
    21601 taatacagta ctatatcctt cacgcatttt aactataaat ttatgtgcat ttgctatttt
    21661 actagcatat ataacttctt catcagtagc ctccagattt ccatacctta tattttccat
    21721 aactgtatca ttgaatatat aaccttcttg tggaactact ccaaaacaag ttctcaaata
    21781 gtttctgtta atagagtata tatccttacc atctaaaagt atacttcctt catctatatg
    21841 ataaaaattt gtaattagat ttataatagt tgtttttcca cttcccgtct ctcctatgat
    21901 ggcatttgat gtgccagctt tgatttttag gtttatatta tctaaaattt tcttttttga
    21961 atcataagaa aaacttacat ctttaagctc aatttctccc tttacaaaat gagagtttaa
    22021 attaccatct ttattatcgt taatctcact tttaaacatg ttatgcactt cttgctcttc
    22081 ttgttcatct ataatttcaa aaactctttc acatccagct atggctgaaa gtaatgtatt
    22141 aaatagattt gctaattcat ttaaaggtct tgtaaattgt cttacataac ttaaaaaact
    22201 agctataacc cctatggtta taatatcttt agatgcaaga atgcctccta taatacatat
    22261 agttgcaaat cctatattac taatcacatt cataataggc attaaaagag aagtgtaaat
    22321 ttgcgattta agggaaatat ttagaattct atcattgact tctttaaaat catttacaga
    22381 ttttctttca taattaaaag attttactac atttatgttt gatatcattt cttcaatatg
    22441 tgcatttagt tttcccaact caacttgttg ttgcttaaaa aaaactctag ttctctttgc
    22501 aataaaatta ctcacaaaca ttactatcgg tattaatatt acactgcaaa aggttaaaat
    22561 tgggcttaat acaaacatca taataaaagt catcaatatg tttaagattc ctgtaattaa
    22621 ctgtactaat gaatttgata ttcctgtact gatattatca acatcatttg tcactctact
    22681 cataatatct ccagtagaac ttttatcaaa aaaggttatt ggtagatttt taaattttaa
    22741 aaataaatta cttctcattt ctttaactat actttgagat aatctagctg tacatatccc
    22801 cttagacagt ttaactgaaa actcaattat ataaaatgaa agtaaaataa ttattccttt
    22861 taagaaaatg gattttgaat aagtatcgat atctattatg tcaactacct ttccaatagt
    22921 atatggtatt acagttgata taattgaatc aattattact agcaaaaaaa taaatctagt
    22981 aatcttctta tcttttttaa agtacataaa aattctttta aacgtttttt taaaatcttt
    23041 aggcttttct tttttcttta atctactgac cttctgattt ccagtactta aattcaatat
    23101 acttcctcct taatttacat cttcacttac taaattctgc aacgcaaaaa tttttttata
    23161 aattggagaa ctaaccagta aatcttcatg tgtagcaaat ccaaccacct caccctcatc
    23221 caagactaaa atcttatcac agtcaattat agaactaatc ttttgtgaaa tagttattac
    23281 agtacatttc ttactttcct tttctcttaa attacttata tactctttta tattctttct
    23341 tataattgtc tctgtattaa tatccattgc actaaaacaa tcatcaagaa ttaatatttg
    23401 tggttttttg gctatagctc tagctatagt aattctttgt ctctgtcctc ctgataaatt
    23461 tttacccctt tggaataaaa cttcatcata agtattttcg agttttgtta taaattgatt
    23521 tgcatttgct atttcacatg attttacaac atcctctttg catatatctc tatttcccat
    23581 aactacattc tccaatatac tttttccaaa cacactacta ttttgaaata ctacacctat
    23641 tcttgccctt aaactttctt cagaaatact gtatatacta cgtcctccaa tcttaatatc
    23701 acctttatca attatatata atttttgaat taaatttact aaagaagtct ttcctgaacc
    23761 agtttgacca atcacaccaa tattttgacc ttcttctatt ttaaaggata cgttttttaa
    23821 tattttttca tctgtatttt tgttatacga aaaatctaca ttttcaaaaa ttatatcaca
    23881 gtttacaaac tttaaatctt tttctccaac atctaaactt tcttctctct caattacttc
    23941 ttcattctca tcaaccaaaa cctcacttat tctctcataa gatgcttttg ccctaacaaa
    24001 aacattaaaa acatgtgaaa tcattataag agatgttaat attctagtca tatagtttac
    24061 ataagcaact ataatcccaa ttttaatttc tcctgaataa attaaatgcc ttccaattag
    24121 taatattatt attatggaaa cattaatgat tattgtaatt gtcggtctaa aaaatgacat
    24181 catagttgta gcttttctac tatttttaaa aagttcatca tttaactctt caaagctttg
    24241 gttctcataa tcgtatctac aaaatagttt aactactttt attccactta aaaactgtct
    24301 taattttgaa tttactttat ctgtactttc ttgtacattt ttaaataatc tataccctat
    24361 cttcatatta agcaatatta taataaatat aattaaaact gcaattagaa taattattga
    24421 catctttaaa tttaatttta tagctataat taaacttcct atacacatta ttggtgactt
    24481 tataaaaact ctcatcattc cattaacgaa ttgttgcatt tgattgatat cattagtaat
    24541 tcttgttatt aatgaagctc taccaaattt atctatttgt tttaatgagt atgtatttat
    24601 cttttcaaat acatcctgtc ttaaatcata agaaaaatgc tgagaaactc ttgccgagat
    24661 tacacttctt attattgcaa atattgcacc taaaaaagtt atacctatca ttatagctcc
    24721 tgttgatagt atgtagtcta agttcttatt tgaaacccct atatctatta tttttgccat
    24781 tatagttggt tgagctaaat cacaaaaagc ttccaatgtt aaaaaaaata ctgctgttag
    24841 aaataatact atatattttt ttatgtattt tttaaaatac ctcattcaat catcccttca
    24901 tagaattttc tcattaccaa aagtatatca taatggctaa tttaattgat tatatcaatt
    24961 ataaatattt gatttattat taatttttat accatatatt ttataaatta tttgttttta
    25021 tttcctatat
//
LOCUS       DAYAKB010000051        24668 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.051, whole genome shotgun sequence.
ACCESSION   DAYAKB010000051 DAYAKB010000000
VERSION     DAYAKB010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24668
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.051"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(578..754)
                     /locus_tag="ACGI3L_002490"
     CDS             complement(578..754)
                     /locus_tag="ACGI3L_002490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198190.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1329..2351
                     /locus_tag="ACGI3L_002491"
     CDS             1329..2351
                     /locus_tag="ACGI3L_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198191.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDVGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2365..3252
                     /locus_tag="ACGI3L_002492"
     CDS             2365..3252
                     /locus_tag="ACGI3L_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198192.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3258..4031
                     /locus_tag="ACGI3L_002493"
     CDS             3258..4031
                     /locus_tag="ACGI3L_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198193.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4143..4868
                     /locus_tag="ACGI3L_002494"
     CDS             4143..4868
                     /locus_tag="ACGI3L_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198194.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4872..6275
                     /locus_tag="ACGI3L_002495"
     CDS             4872..6275
                     /locus_tag="ACGI3L_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198195.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDDGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6286..7110
                     /locus_tag="ACGI3L_002496"
     CDS             6286..7110
                     /locus_tag="ACGI3L_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraX family protein"
                     /protein_id="HFG9198196.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNT
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7435..8055)
                     /locus_tag="ACGI3L_002497"
     CDS             complement(7435..8055)
                     /locus_tag="ACGI3L_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9198197.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8321..8653
                     /locus_tag="ACGI3L_002498"
     CDS             8321..8653
                     /locus_tag="ACGI3L_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9198198.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8773..9414)
                     /gene="pcp"
                     /locus_tag="ACGI3L_002499"
     CDS             complement(8773..9414)
                     /gene="pcp"
                     /locus_tag="ACGI3L_002499"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFG9198199.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9435..10367)
                     /locus_tag="ACGI3L_002500"
     CDS             complement(9435..10367)
                     /locus_tag="ACGI3L_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFG9198200.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10389..11054)
                     /locus_tag="ACGI3L_002501"
     CDS             complement(10389..11054)
                     /locus_tag="ACGI3L_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFG9198201.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLRQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11626..12102)
                     /locus_tag="ACGI3L_002502"
     CDS             complement(11626..12102)
                     /locus_tag="ACGI3L_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HFG9198202.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(12105..12509)
                     /locus_tag="ACGI3L_002503"
     CDS             complement(12105..12509)
                     /locus_tag="ACGI3L_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HFG9198203.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12484..13113)
                     /locus_tag="ACGI3L_002504"
     CDS             complement(12484..13113)
                     /locus_tag="ACGI3L_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9198204.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      13479..13522
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13623..14591
                     /locus_tag="ACGI3L_002505"
     CDS             13623..14591
                     /locus_tag="ACGI3L_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFG9198205.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14593..15156
                     /locus_tag="ACGI3L_002506"
     CDS             14593..15156
                     /locus_tag="ACGI3L_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9198206.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            15164..15853
                     /locus_tag="ACGI3L_002507"
     CDS             15164..15853
                     /locus_tag="ACGI3L_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9198207.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15980..16708
                     /locus_tag="ACGI3L_002508"
     CDS             15980..16708
                     /locus_tag="ACGI3L_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFG9198208.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAQDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16722..17396
                     /locus_tag="ACGI3L_002509"
     CDS             16722..17396
                     /locus_tag="ACGI3L_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9198209.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17422..18258
                     /locus_tag="ACGI3L_002510"
     CDS             17422..18258
                     /locus_tag="ACGI3L_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198210.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18274..18945
                     /locus_tag="ACGI3L_002511"
     CDS             18274..18945
                     /locus_tag="ACGI3L_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198211.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLINQNIY
                     DLVILDLMLPNINGFDILKKMRINNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18935..20167
                     /locus_tag="ACGI3L_002512"
     CDS             18935..20167
                     /locus_tag="ACGI3L_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9198212.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20317..20634
                     /gene="trxA"
                     /locus_tag="ACGI3L_002513"
     CDS             20317..20634
                     /gene="trxA"
                     /locus_tag="ACGI3L_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFG9198213.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20651..21529
                     /locus_tag="ACGI3L_002514"
     CDS             20651..21529
                     /locus_tag="ACGI3L_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9198214.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21799..22167
                     /locus_tag="ACGI3L_002515"
     CDS             21799..22167
                     /locus_tag="ACGI3L_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFG9198215.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            22170..22541
                     /locus_tag="ACGI3L_002516"
     CDS             22170..22541
                     /locus_tag="ACGI3L_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HFG9198216.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22686..23141)
                     /locus_tag="ACGI3L_002517"
     CDS             complement(22686..23141)
                     /locus_tag="ACGI3L_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198217.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(23180..24445)
                     /locus_tag="ACGI3L_002518"
     CDS             complement(23180..24445)
                     /locus_tag="ACGI3L_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HFG9198218.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMADIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9535 a         2735 c         3799 g         8599 t
ORIGIN      
        1 aaaaatatta aagttaatct acaaatatag aatatattct aagacgaatt tttataatta
       61 ctaaataaaa taaattaatc aatatagttt tttaatataa acaaaaaata aaaaacttat
      121 ataaataaaa tgcttgtttt tcttgtatta tttatataaa tattgaaatt tgtctagtta
      181 tacgttttta ttgaccagtt atgcagttga tattgaatat tctaaatatt ggtgttattt
      241 tataggtggt ttaaacatat tagggggatt ttatatatga tttgtatgat ttatagagaa
      301 tgtataaaat agtaaaggtt tagagccatg tttagtggat tgcagaatat gcatatagaa
      361 tgattcttgt aaattaagtt agacatagga aatatataat ttgtattgga tgattaattt
      421 tatggtgtat gcttttaact tctataatgg gaaagtaaag atgtactccc aatacatctt
      481 tactttagca gaagttatag ttacttataa agtacaaaaa attatatatt tattagagta
      541 gataaatcta aaaaggtttt tctagaaaaa tttagtttta attgtatcta cttactaata
      601 ataagacttg atgtaagcag gtttcaacta ccgtttctcc atattctgat ataaaatcat
      661 ctaactgtgt atctaaaaaa ttacaataat catatgaact actgatgtaa gcagttagta
      721 tatgtgtaca tttgtctatt tctccaataa acatattatc catcccccta aaaaatttag
      781 taaaaataaa aagtcgcatt ctattagtca attaacataa tttataaaat tttttagtac
      841 tagtttctat aacttaactc cttaaggtta aatattccca gttttaccaa tttagtttta
      901 ttctacaagt atataatact agaagatgct ccattattca acatgcttgt ttgagaatag
      961 aaaatattct aaaattataa ttgtttttaa aaataagatt caagataaat aaagttatat
     1021 gcaactattt aataatcttt ccataataag gacagtaggt tctattctta aaaaactcca
     1081 tctttaaatt taaagaataa ctacaatttg aacaacaata aaatttccaa tcaataaaaa
     1141 tatcaaaaat aataaaaata attgaaaatg tataatttcc cagaaaaata ataaatgtaa
     1201 ctccaataat aaacacacct ataaattata aaataattta agctttattt aaggttagta
     1261 ttatatttat ataagattta agttttaata tatatgtgta attaaaatga tttaggagga
     1321 gaaatatatt ggtaaattgg gaaataaaaa aattggctaa atctaagagt atgtttatat
     1381 ctctagggat attagtgtta atactaatga ttagtatctt tattacgcct gttttagaaa
     1441 cagaaagtta ttatatagat aaagaaaaag gacgtataga agatacgaga agtggtatcg
     1501 acgtaggtaa tgagaaattt caaaataaga ttaatgtttt aaagcagttt tcaaatcaaa
     1561 cagatacagg tgaattttct aaaaaaattg aattaatgtc aaagaaaaaa cttgataatc
     1621 taagtgtgaa tgaatataag gatattagtt tttggaaagt atttaactat agagtcacaa
     1681 attcacttat aaatgtagga atgttaatca ttatatctat aattatatcc aatatttatg
     1741 tagatgaagt cgttacttcg gtaaaagata tcatactatc atcaaaagag aagaaaaaag
     1801 cattaaagtc taaaatattt gttgctttat tagttccatt agtaatttat tctgtttatt
     1861 taatgggaat atttattata acttgtatgc aacaaggagt acctgttaat ggagacttag
     1921 aatcttttag aatagtagac aatgtagttg cattgaaaac taatttaagt ataacaaagt
     1981 atgtaatatt aaatataggc atagagcttt tgatgtttga aggatgggcc atgatagcca
     2041 tatttgggtc ttttataagt aagtcttcaa tatcttcaat aagttttttt atatttatta
     2101 tatctataac taagataatg tcggtaatcc atatattacc taaaaaatta ctttcagttg
     2161 tatcaaatgt aaattattat gatttgatat ttggttttaa taaaataata ggaaattatc
     2221 taggtgatat tatgatattt aaagtgaata tagacattgt caatatagca ataggacttt
     2281 tgatggcaat attgataggt gctatgtcat tatgtttttt agtaataaaa tcagattata
     2341 taagtagata aaaggggagt taagatgaat aaattagaaa tagaaaatct ttcaaagata
     2401 tatggtaaaa aagtagcaaa cgacaagatt acagtaactc tggaaaatgg agtttatggt
     2461 cttctaggac caaatggagc aggaaaatct acattaatga aacaaataac aacgttgata
     2521 aaacctgatg aaggtcagat actttataat ggtgaggata tatttaaaat ggatgctgat
     2581 tatagaaata ttttaggata tttgccacaa gaatttggag tttataaaaa ttttacagca
     2641 aaagaatttt tacagtatat tggagcttta aaaggtttaa ggggaaaata tttaaatagt
     2701 aagataggag aattattaga tttagtaggt ctttatgatg tgagaaataa gtctatagga
     2761 aaattttcag gaggtatgaa gaggagagtt gggatagcac aagttttact aaacgaccct
     2821 aagataatag tccttgatga gccaacagca ggacttgacc cacaagaaag agctagattt
     2881 aggaatttaa tagcaaaaat gtctagagat aagataataa tactttctac tcatataatt
     2941 tccgatatag aatcagttgc aaaggaaaca ataatgatta aagatggcaa actcctaatg
     3001 aaaggaacac acaaagacat attaagtcac atggaaaata aagtatataa tgttcaagtt
     3061 aaaaatgaat gtgaagttga tgatatacaa tctaaatata aggttgtaag tattcaaagt
     3121 gatattgatt cagtagtact tagaattgtt tcagaggata ttccaagcga ggataatata
     3181 caaccagttc aagcaaaatt cgaagatgta tacatgtttt attttgattt agaagatgca
     3241 agggaggtgt agtagaaatg atgtatttag ttaaagctga aatgataaaa atattaaaat
     3301 caaagagtgt ttggataatt tggctgtttt taatattttt tggatttttt ctgattagaa
     3361 agtttgatgt tttagatact tatgcagata tattttacaa gatagaaggc tcaatacctc
     3421 taataggttt gataatgttt ataataactt ctggaaatta cattaaagaa tatgattcta
     3481 atatgacagg tttaataaat acaactaaaa agggaaaaaa atcagtagta ttatcaaaac
     3541 tagtagctaa tggattaatt ttatctatta ttaatatttc ttttatattg ttagtaggaa
     3601 ttagaggttt tagttttttt gattttaaaa atttaaatga atcgattcat aacttatggt
     3661 actttggaaa tagtaattta aatcttacag taatacaaat gtatataatt gttatattga
     3721 ctactatttt tgcttctttt atatttgcac aaataggctt aacactttca tctatattta
     3781 aatcggctgt aattccattt atactaggtg gattgataat ggcaattcca tactttagtg
     3841 taggttttat accagataaa gctataaaat ttatgtcagt gactccaaat tggattatga
     3901 tgagccaaca aatggttaag tataatgtac caagtatttt gatagttttt tctatagtaa
     3961 tctcaattat attaatgata gtgttaacta aaataacata tgaaaatttt acatcaagca
     4021 aaaggtttta actaaaaata atagtaattt tatttatatt ttagtttaat taaaaataag
     4081 ataaatgaat tttagataaa atatatgcta atatatatgt aaattattac aggaggttgt
     4141 ttatggaaaa tcgtgtttta ataatagatg atgaagtaga aatattgaag cttttagaaa
     4201 ctgtcctaaa aaaagagggc cttaataata tatatactgc aaaaactaaa aaagaaggat
     4261 tagaattatt taaaagtatt aatcctgatt tgattgtatt ggatattatg ttaccagatg
     4321 gcgaaggtta tgatatttgt aaagaaataa gaaaaacctc caattctcca ataatatttt
     4381 tatcagctaa aaccgaagaa ttagataagt tacttggact agcgattgga ggagatgatt
     4441 atgttacaaa accttttagc cctaaggaag tggcttttag agttaaagcg catttgagaa
     4501 gattaagtta ttttagtgat gctcaaaacg aaagtaaaaa tctaaataat aatgaagaaa
     4561 aaattatatc atttggccca tatatattaa atgaaagtag ggcagaactt ataaaagatg
     4621 gaaaatctat aggactgtct gcaaaggaac taaaaatcct atctttattt gcacataatc
     4681 aaaatcaaat tataagtaaa gaaaaactat gggataaagt gtggggagaa gattatgttg
     4741 gatttgacaa tactataatg gttcatataa gaaaaattag ggaaaaatta gaggataatc
     4801 cttcaaagcc tgaatatatt ctgacaataa aaggtcttgg atataaatta gcagtaaagg
     4861 aagattagaa tatgaagtgg aagattacta gaaattttat atttacaatt gtgtttgtag
     4921 ctatatcagt agtaattata aatatcatat ctatattgta tgtgatttca actaatagtt
     4981 tttttaaagt tgtagattct ggaaataatc ctgaagaatt tgcacgttct tttgaaaaag
     5041 atttatatga aaaagatgga gaatttaaac tatctaagat tggagctgaa aaattagaaa
     5101 aatcaaattc ctggatacag gttttaaatg atttaggaga ggaagtttat ggagtaaatg
     5161 tgccaaagga tactcccaaa aaatatacac cctttcaaat ggtgaataat tacaagtata
     5221 tagaaacaaa gtatgttaat tttgtattag aaaaatattt aaacaaaaaa catctaaaca
     5281 taatagtagg tatacctagt agagatatat caagaataat tttaacctat tctcaaaata
     5341 acattaaaaa aactttaaat aaagttatca ttataacact agtaattgat agcgtggtag
     5401 ctttaggtgt aggatattta tttagtagaa aacttacaaa accaatttca agcgtactat
     5461 ggagtattga gactatggct aatggaaatt atagtttata tcttaaggac agaggtatat
     5521 atgaagaagt ttttaaaaat ataaatatgt tagctgatac tttaagagta aatgaagttg
     5581 agagaaaaga aaatgaagag ttgagagagg aatggttggc aaatataaca catgatataa
     5641 agacacctct agcatctata caagggtatg cagagataat taatgacaaa gattatgagt
     5701 ttgaagaaga tgaaatacaa gagtatacag aaattatata taataagtct aagtatataa
     5761 aagatttagt tgatgattta aatttatcta ctcgattaaa aaataatact atagttctgg
     5821 acaagaaaaa aataaattta gtcagtttag tcagagatat aataattgat attttaaatg
     5881 ataatagata taaaaatagg aatattgaat ttgaaagtaa tgaagattta attgaagtat
     5941 atgtagattc aatcttattc agaagggcta taaccaatct tatatttaat tcaatagttc
     6001 ataatagcga aggaactttg ataagtgtag aaattgtaaa aaaagataat atagaaatta
     6061 taataaaaga tgatggaatt ggaataagca aaagtgattt gaaacatatt tttaaaaaat
     6121 attatagagg tactaataca ggtgagatgc ataagggttc aggtcttggt atggctattt
     6181 ctaaagaaat aatagagatt cataaaggta aaatttatgt aagtagtgaa attggaatag
     6241 gaacaaaaat tattatagag ataaaacaaa attaggagat atgatatgga tttttttaaa
     6301 aaaggtataa gtgggtttac tattaagatt ttagcattaa tatttatgac atttgaccat
     6361 atagcagcat ttatgccaca aacaatgcaa ataccaattt ggtttcattg ggtaggcaga
     6421 atatcagcac cactgtttat attcatggct gttgaaggat tttatcacac tagtaacaga
     6481 aaaaaatata taagtagatt gtatatttgg tctgttatta tggctatagg aaatcaaata
     6541 attaataatg tattttcaca tccagaagga gctataatta taaataacac tttttcaaca
     6601 ttatttttaa tagcgattta tttacaagca atagagttca taaagaaatt tagaaaagag
     6661 aaagaaatta aatattttat tataggatta ttgatgataa tcattcctat aattttagga
     6721 atatttacag tagctttact ttttaaagtc actaacagag ttattgcttt atttatgatt
     6781 ttggtaccag taccattttt agtagaaggt ggaccaattt ggattatact tgggattatt
     6841 ttttatttgt gtagaggtaa aaagttcagt ttgagtattt gttatgtttt aatgtgtata
     6901 tttatattta caacaatgtc aaatggagat tatagtttaa aaaattctat tttacaaaat
     6961 taccaatgga tgatgattgc ttctctacct ttaatgttac tttacaatgg agaaaaaggg
     7021 aagagtatga agtatttatt ttatttatac tatccaatcc atgtatatat attgtatatc
     7081 ttaggaatat acttaataaa tggtttttga ttgtaagtga tatttttaat acaaaatgaa
     7141 cagtatgagg attgttttag gtctattaaa attgttattt agatgagatt tgtagaatat
     7201 ttaaatttat gagcagaaat tcagttattg taatttcaat aacattagaa tataatatta
     7261 taatttattt agaaatatat gatgttatac atggtttggt tattaatgta ataataaaac
     7321 agaggtttga tataaaattc aatacctctg ttttagtgct ttttatccta catttatgct
     7381 tattttattt ataaattagt gttttgtttt aattaatatt agtacatttt ttatttattt
     7441 tataaaatta gtcataattg tttcttcata ttgtggttct ttaattccag cttttttacc
     7501 tgctgatata cacttaagaa gccatgccat gttttctcct agagttcgca tagtctgtaa
     7561 tccttcttca tccttcataa catcctctgg agtaaagcca tgtacctggt tccaatactg
     7621 tgatgataca ataggcatat tgctgattga aaaatattta tttagttggt caaatgttgc
     7681 acttgcacca ccacgtctac atgacacaac tgaagcacct aattttgtag ccatgcgact
     7741 cccagctatg aaaaatagac ggtcaagaaa agaagttaat tgaccagttg cactagaaaa
     7801 gtaaacagga gaaccaataa taataccatc aatattatcc agatcttcaa tcaattcatt
     7861 aactttatca tttcgaatac attttccagt ttcaaaacag gatgcgcaac taatacatcc
     7921 tgggattgtt tctttaccta aatacagtat ttctgtttta atatcgtgtt tactcaatac
     7981 tttagtaatc tcatttagtg ctgtataagt acatccatat tggtttgggc taccgtttat
     8041 caataaaact ttcattataa atttcctcca atgaatttta tttaatagat tttctaagag
     8101 acattatttt ttataaaata ggattttcat gaatattatc aatttatata gaaatgtcta
     8161 atcttagaat cctatttaaa ataacttttt ttttagtaaa tacacctcct attataaaat
     8221 tgactttcaa ttattcttac actataattt tattataaat tattctaaaa acaagtacgc
     8281 acatttttgt tcaatactaa ccaaaaggag agtgtaatat atgagtatag actgtatatc
     8341 aaatacagat ttaagtgaaa caggatttag ttatacactt tcactgatta gtggtaaata
     8401 taagatgata attctttact gtcttgtaga atttgaagtt gtaagatata atgcattaaa
     8461 acgttatata aatactatct cctataaaac tttgagttta tcattaaaag aattagaagc
     8521 agataacttg attattcgta ctgaatatcc tcaaatacct cctaaggtag aatatagtct
     8581 atcagaaagg ggaaaatctc tgattccaat tttagatgca atgtgtgagt ggggagagag
     8641 gaatagacct taattttgta tctgtagata ccataaaaag actgtgagta aaattgtttg
     8701 aataatctac tcacagtcta tatttaaatt aatagttagt atttttaatt tataaaaata
     8761 ctaaaaaatt tattatgaaa tttcaccacc aatttctttt acatcttctt tatatataat
     8821 acaagcttct atagctaatt ctaagccttt tactatttct tctaaagaca tgaatggtgt
     8881 atttttttta tctattactt gtgaagttgt atatgggatg tgtataaatc caccccttat
     8941 attaggatat ttcttgtcta tcatataaag aattccatac atcacatgat tgcaaacaaa
     9001 tgttcctgca gtgtttgaaa cactagctgg aattttattt tcattcatat gttttaccat
     9061 agcttttaca ggcaattttg aaaaatatgc aggttcacca tcttctttta taatagtatc
     9121 tataacctgg ttaccctcat tatcttttat tctaaaatca tctatattta tagcaactct
     9181 ctcaggtgta atgtcaaatc tacctccagc ttgtccaact gatattacta tatctggatt
     9241 gtgctcttga atagctttat ctatagcttc aacagatttt gtcataactg ttggtatagt
     9301 tatctttatg atttctgcac cgtttatatt attattgacc ctttcaactg cttcttgagc
     9361 tgggtttatt ggttctccgc caaatgggtc aaatcctgtt aacaaaattt tcattatttt
     9421 acctcctaat tatattaaaa tcctaaaaag tacattacta atatgtgggc tataattaat
     9481 accaaagcaa ctggagcttg atattttata acaatataat catttttaca ttctagcaag
     9541 gctgctggaa ctatattaaa attagcagcc attggagtaa gtagagttcc acaatatcct
     9601 gctgttaatg ctaatgctcc aattatagca ggatttccac cttgagacaa tacaaaagga
     9661 ataccaattc ctgccgttat gactgaaaat gcggcaaatg catttcccat tatcatggta
     9721 aatataacca tacctaatac ataagctata acaccaaata atctgctatc agcagggact
     9781 acaccagata tcatggttga aataacttca ccgactccgg cttgagtaaa taaagctccc
     9841 aatgcaacta aaagttgtgg taacatacta gcaggtccca tttgttgaag taatcttgag
     9901 ccatcttgaa ctgatgtagc aggttttgcc ttagttatta taagggctga tattaatgca
     9961 attattgaac ccacacctat tgcaaactga gaagaattat caaaattaga aagactcata
    10021 gctactacta ctgcagcaaa tgctaatatt aatgatggta taaatatttt atttttaagt
    10081 ttgtctgctt gttcttttcc aaaattttca tctggttctt catactttgc aaatacaact
    10141 tgtttagaaa gtgttaataa actagataat attaatatta ttcctattat attggctgga
    10201 atcaatctac caaatatgaa tggcagtgat ataagtatcc aaaataatga tgtaccatat
    10261 ttcttattgt tatttatggt agtaaaagac ttatatgcta taacaatcat taaaaatccc
    10321 attagtgcgt aaaagatttc caatgatatg tttataaaat tttgcatttt tattcctcct
    10381 aaataaaact attttttatg acttttgttt aattttttat catataaggt aaactggatt
    10441 gtagccacta caagtgctat tactgccata atagtactag cctttacgat attaagtcca
    10501 gttacattgt atccaaattg agtcagagta gatgctataa gtaatactcc actactacct
    10561 gcaaataagt tttgaccata aaaatttcca tagttttctg atgcagcaga taatgccttt
    10621 atggcttctt catccgattc ttttagttca tcactattac ttaaaccagc agcttgtgcc
    10681 ataggattaa caagtggtct tacaaattga ggatgtccac tcattcttat tgatagagca
    10741 ccagctattt gtctagctat catgtatata gtaagtactt ttcctgttgt aagtcttttt
    10801 aatttttcta ttaaagaaac agctctttgt cttaaaccat atctttctaa tacaccgatt
    10861 actggcaatg ttaatatgaa taatgataca cctctgtttg agacaaaaga atctcctaaa
    10921 attgtaaaaa tttgattaaa atctaatcct gcaacaattc ctgttgccac tcctgctaat
    10981 aatacagtaa atagtgtgtc aattttaagt ataaatccaa ttacaactat caatataccg
    11041 attagtttta tcataaattg ttctccttcc atttctatat gttttaattt aaatttattt
    11101 aatggataaa gttaaactct ttttatagta tttgcgttaa taggactatt attataaaat
    11161 ttaataaaaa atagggaaga tgttttaaag tatcaaagta aataatggtt gtgtatagga
    11221 atttgaataa caaagattat attttaagct aatatgaatt gattttgtaa gtctatagtt
    11281 taagtatatg tcaatatttg aaatagtagt tttaaattaa acattatatt ataaaaagag
    11341 aatgtgccaa acatagagac aagtgtattt ttctctgttg aaatgataaa aatatatttg
    11401 atttcataca aaaagagagt gtctaatgaa ttttttagtt cattagacac tctctttttg
    11461 ttatgattaa taaaacatat ttgttatgat taataaagca tatattaagt gctagtttca
    11521 ttagatttca ctaagaaaaa taaaattttg ataaagttta aagactattt tgagcaatat
    11581 tacttataaa taaaagaatt tatcatagaa ataattagct ttattttagc tattaagatt
    11641 tattaaaaaa ttatctatat tatcctgtga tattctaaaa ctgtcataat taccttttga
    11701 aacagccttc ataataagtt tatctaaaaa tttcattttt tctaatcgag cttcactacc
    11761 aaaaattcca atagcatttg cactttctaa taaggatgat ggaaaatttg attttaaata
    11821 tttatctgct tgttcagaaa agccacagca aaggaaaatg ccaacttgtt ttttgtttaa
    11881 taactctaca ttatcattac atagcacctg tatttttttt gaaactgaac caacatatat
    11941 agaacttcca ataataattt tatcaaattt tgataactca attttattat tattattatt
    12001 aatatcaaca atagtgacat tatctgatag tttatttttt agtatatttg cacagtcttt
    12061 tgtacaacca tatttacttg aatatataat aatagtattc ataattattc tccctttctt
    12121 aaagcatttt ctacagcttt tcgtatagta ttactgctat aagttgcaga agttatagca
    12181 tccacatcta aagactgttg tttaataata cttgttgtaa ttttttcagc aggtttacct
    12241 aaaagatggt cgtgttttaa gatattaata ttttggattt taccattatt aacttcaaca
    12301 gacacagtag cttttaccaa gttattatca gcacttccag tataaatgcc atttttaaca
    12361 ttattaatat ctatatcttt tactaccaag ttttctggct ttaagttgct tacaattaca
    12421 ataataatgc atataaatac aaagaataga gcaatagata tttttacata ttttttcttt
    12481 ttattagtag ccttgttgcg aattttcatt gtaaagtcct cccactaaaa tatctaagaa
    12541 attttctata agttgagaaa aattatgtaa agaatatagt ttattttcaa caacacataa
    12601 aacgaatcct aacaatgcac ttataagcat ccatgagctt ttatctatat tttttttgaa
    12661 tattccttgt tcaattccaa tggaaaggaa tttatcaagc atttttatac cattattgct
    12721 aggcgtattg tttgtatttt cagatgcaaa tataatattc attctactat gcatgataga
    12781 ttttgccatc tctggttcac tagaaagagt ttttataaag ctagtcataa tttctatgat
    12841 ttgtttatct attggtagtg atgagcaatt attcataatg tcaatggcat tactttctac
    12901 tgtgttataa agtttattgg tcatatcgct gataatctct gctttgtctt tgtagtaaag
    12961 ataaattgta gttggagaat attctatttt tgtagcaatt tttcttattg ataaattttc
    13021 atatccatgt tggtttataa tttcgatgct agcatccata atctttttct tcatttcttc
    13081 tttttcattt ttacgtcttt ctttgatact catataatca cctctttgct taacggtgtt
    13141 aagttaattt acactgttat tgtataattt aattttaata ctgtcaataa attattaaat
    13201 aatataagtt aatatatttt tatggataat aaattaatgt tattaattgt aatatttaag
    13261 atattattgt ataataataa tcggtttaaa tgcgccacat cttattaaag ttggttcata
    13321 attctaaata aactttaata agatacatta aaatataata aattctttta tgctataaaa
    13381 tttattttat agctattaaa tcagatgttt aaaaattttt taacggtcta tagtttttaa
    13441 gagtcttata gtaagtagcc taaaaatatg attttacatc tgtacttgtt cgagaactcc
    13501 aagtataaaa aactaaggaa ttatatagtg gcagtatata attaataccc ttagacacac
    13561 ctttttgaaa gtggaaaaaa gatgtgtagt tctcctcgac cacaaatcaa ggaggataaa
    13621 aaatggaaaa gagaaaagta ataattgatt gtgacccagg aattgatgat tctttggcaa
    13681 ttcttctggc tttaaactca ccagagctag aagtaattgg aattaccaca tgttgtggaa
    13741 atgtcccagc aaatataggt gcagaaaatg cactaaaaac acttcaaatg tgttcttcac
    13801 taaatattcc agtatatata ggagaagaag caccactaaa aagaaaactt gtaacagctc
    13861 aagatacaca tggagaagat ggtattggag aaaactttta tcaaaaggtt gtaggagcta
    13921 aagcaaaaaa tggagcagtg gattttataa taaatacttt atataatcat gaaaaagtat
    13981 caataatagc acttgcacca cttacaaata tagctaaagc acttattaaa gataagaaag
    14041 catttgaaaa tctcgatgag tttgtatcta tgggaggagc atttaggatt catggaaatt
    14101 gctctccagt agcagagttt aattattggg tagacccaca tggagcagat tatgtttaca
    14161 agaatttatc taaaaaaatc cacatggtag gtttagatgt aactagaaaa attgtactta
    14221 ctcctaatat tattgagttt ataaatagac ttgataagaa gatggcaaag tatataactg
    14281 aaataactag attttatatt gatttccatt gggaacagga gggaataatt ggctgtgtga
    14341 taaatgaccc tctagcagta gcatacttta tagatagaag tatatgtaaa ggatttgaat
    14401 catatgtaga agttgtagaa gatggaatag ctatgggtca gtctatagtg gattctttca
    14461 atttctataa aaaaaatcct aatgcaattg ttctaaatga agttgatgag aagaaattta
    14521 tgtacatgtt tttaaagagg ctttttaaag gttatgaaga cattatagac tctgtggaag
    14581 gagtgatata gtgtgaaaag aaaaatatgt gtaaaaacta ttacacttat agcttttggt
    14641 atttctataa atataatagg cgcttttata gctatgggat taagattacc tgtatactta
    14701 gattcaatag gaactataat gatagcttca cttttaggac ctaaatacgc tgttgttaca
    14761 ggtgtgtttg gaagtttaat aagtggaatt acgtttgatg tgtattctct ctattttgca
    14821 ccagttcaaa tatcaaccgg attacttgct ggaatagcat ttaaaaagaa ttttttaagg
    14881 ggtttaaaaa ctccactagg agtactttta tttgccattc caacatctat aataagttca
    14941 ataatttcag catttttatt tggaggtatg acctcttcag gttcatcata tatagtgcaa
    15001 atcttgaaag tgttaggact gggggatgtt tttagtgtgt ttgtaaccca agtatttact
    15061 gattatggag ataagctgtt agcagttgtt ttagtgaatt taggattaaa tgcagttcca
    15121 aaaactttaa aggtatcatt gactggagga aaatagatag aaaatggata gatatagtga
    15181 gataacaaat aaaaatcaaa gagaaattgt tctgcttaaa ggatttcctt gtatatgggg
    15241 aaagtgttct ttttgtgatt atatagatga taattctaat ttagaagaag agatgaataa
    15301 attaaatcta aaggttttaa aaaacgtaac tgggaaatat ggagttcttg aagtcataaa
    15361 ttctggaagc tgttttgaat tacctaagga tactttagaa aaaataaagt gtattataaa
    15421 agagaagaat ataaaaaaat tatttttaga aagtcattgg tcttacaaaa ataggcttaa
    15481 ggaaatgaga gagtattttg aaattcctgt ggtatttaaa attggagttg aaacctttga
    15541 caatgatttt agaaataata ttttaaataa aaatgcaaat tttaagactc cacaagatgt
    15601 aaaagaatat tttgattcac cttgtattat ggttggaata aaaggacaaa caaaagagat
    15661 gatagataaa gatatagaga ttatcctaaa tacttttgaa aaagcgacag tgaatgtttt
    15721 tataaataat tcttctagta taaaaagaga tgaagagtta gtgaaatggt ttgttagtaa
    15781 gtataaattc ttggatgaaa atccaaatat agaagtttta tacaataata cagactttgg
    15841 tgtaggagat tagcattaat ttagtttaaa tttaaaattg aaaagtttct tatgtttttg
    15901 aaaaagcttc taatagttag aagctttttt tgtagagttt tatgttacaa taagaaaaaa
    15961 ggaattaagg agcaattaaa tgatgtttga taggggaaaa tggaataaat tggattataa
    16021 tgaactttta gaatatatga tgtctataca agatataaaa tatagagatt ttaataaaaa
    16081 gcttatacct ggaacagaaa atataatagg tattagagtt cctaatttaa gaaagttatc
    16141 aaaagaaata agccaaggga attggaagga atttttagaa gtagcacagg atacatacta
    16201 tgaagaagtt aggctacaag gtatggtaat tggcaatata aatagtaatt ttgaagaaac
    16261 tttatactat gtaaaaagat ttatacctaa aatcgataat tggtcagttt gcgatggatt
    16321 ttgttctgat ttaaagtcta tgaaaaaata taaagaaaat atgtatgata tacttaaaaa
    16381 atatgtttat tcaaagaatc catgggaaat tagatttgca ttagttatgt ttttaatata
    16441 ttatgttgat gataaacata ttaaagaaat atttgaatac tgtaataata tacaaagtga
    16501 agaatattat gttaaaatgg gtatggcatg gttgctatca atttgtttta ttaaatgtga
    16561 agaggaaact tttctctata taaaaaataa taatttagat gatttcactt ataataaaat
    16621 gctacaaaaa ataattgaat caaatagagt agatttagaa aagaagaata taataagaag
    16681 tatgaaaaga aagacaagaa gatgttgacg gaggaatatt aatgaataac aatgaagaca
    16741 gaattgacaa atttttagaa cttcaaagca aaggatttaa atttgcagag atagctcaaa
    16801 atctaaagat tagtcaaagt actttaagaa cttttttaaa taaaaaagga tataagtcag
    16861 aaaaaggtaa atacatatta aaagacgaat taaattataa taaaagtttg gataatagaa
    16921 acttggaaga agagaaagct aaggagtatg aaaaaagtaa aaagaatact ataagtaata
    16981 gaaaaaaagt aagcaccaaa aaaaagattt ctaatgaaaa ggctttaagt aaaagtgttg
    17041 aacaaattga gtttaatgat acaggtttaa aaaatgcaaa gccaaaacaa aatattaagc
    17101 ctaagaaaga tagaaaaata aatataactc aagaagattt agataagctt tgtgaagtat
    17161 atgattggta tttagaagta aaagattaca atataaagcc taaaaaagta tctaataaaa
    17221 aagatgtaca tatagatgat gaacacatag atgaattaaa aacaacaaga atacgtatag
    17281 ataaagaaat atggaatgat tttgaaagat tatgtagtaa ttcgaatttt gaaaaacatc
    17341 aaatacttac acaggcattg aaagaattta tgaaaaagta taaaaatcta ctataaaata
    17401 ctactatatg aggtgcttaa tatgaataaa atagtaaaaa aatcaatttc tctaatgatt
    17461 atattaacaa tatttatttt tatgttgaca gcatgtgaaa aagatgaaca gcctgattca
    17521 gttgatattc aaacagaaga taaaaatgag ataaaaatag atgagggaaa tgcaaaagta
    17581 ttgaatatag gaaaatcaga aattataaat atagatgaag gtgataaagt agatacatca
    17641 acaaaggtag aaaataattc aacatttaat atatccaatg ttgaattgat atataatgaa
    17701 tatgatgaga ataaaaaaat tatatcttcg gatagtaagg ctttgttgga catgacttta
    17761 atgcctggga aagttgctta catagaatgt gggcataaaa cttttgtaaa gggtgtagaa
    17821 gtttatgcat atgaatatga ggcagagggt aagattgtgt atgttaattt aaaagaaaat
    17881 actattaata taagaaataa taatattaag ctagaaaata gtagtcagta tgaggtgcta
    17941 tctacatcag aacttaaaaa agtaaatgaa tcaaatgagg gaattacgta tcaagtaaaa
    18001 gtaaaaaatt catcatcaaa agatttagga aatattattc ttaagacagc agaagttaat
    18061 gaaaatggag aatatttaac agtaaatcgt gtaccatcat ataagatttt aaagccttca
    18121 gaagagacag atatagatat attgtgttca acaaaggcaa aaagtgttga aatagtggga
    18181 tatacgtatg atgatataaa agaaaaagcc aatgtggata ttgacttaaa atctcataaa
    18241 gttaagatag acaaataaag gtaggggata cttatgaagg ttttaatagt tgaagataat
    18301 aagatacttt tagaaagtgt agtagaagaa cttagcaagc attttgaaac tgaaaagtgt
    18361 gaagatggag aagaagcttt atacttaata aatcaaaata tatatgattt agtcatttta
    18421 gacttaatgc ttcctaatat aaatggattt gatatcctaa agaaaatgag aattaataat
    18481 atagatacac ctgtacttat attgacagca aaagaaacat tagatgacaa agtagaagca
    18541 tttactatag gagctaatga ttatttgaca aaaccttttt atatggaaga gttagtagct
    18601 agggtatacg ctatattaag gactaatgga aagataaaag aaagaaacgg attagaattt
    18661 aaatctttat atttagatac actagaaaaa agagtgtata ttgaaaaaga agaaataaaa
    18721 cttcaaaaca aacagtttaa cttgcttgag tattttgtat taaataaagg ttcaatttta
    18781 ttaaaagagc agatttatga tagaatatgg ggaattgatt cagatgcaac tattgaaata
    18841 gtggaagtat atgtaagtaa tctaagaaaa aagctaagta aatatggata tgataaatat
    18901 attaaaacta aacgtaaggt aggatatata ttcgatgata aataagaatg tatttaccag
    18961 tactaaaaat catttaataa aaatgtatat tattgtagta ggtagttttt taataatctt
    19021 ttctatattt atatactcat attttagggg acttacatat agtggaattg atagtgagat
    19081 aaatgatgaa cttgaatata tagtctctca atttaaaaga acttcatttt tgaacccaat
    19141 aagactcaaa gatcctaaag atatggtgta tgtatatgaa gatggaagga taagttacta
    19201 tactcaaaat gaatattttg atgagttact tccagataga agactagata aaaaaaattc
    19261 gttttttaaa tacacagaaa atggatatac ttttagagaa ttaaatgtag atgtaggtag
    19321 ataccaaata cagataatta gaaatataga ttctgagatg aattctttaa gacagcttac
    19381 atctgttctt ataattggaa tattaatttc tgtaataatt acttactttg tggctgtata
    19441 tctcactaga aaagctttaa ttccaataga aacagcatgg aaaaatcaag ctaagtttat
    19501 acaagatgct tctcatgaat taagaacacc aataacaata gtttcatcaa aattagaaag
    19561 tatgttaaaa tccccagaaa gtacagtaaa tgatgaagtt gaaacaatag ctactgcaat
    19621 gaaggaaact agaagactta aaaaaatgat aactgattta ttgtctctta ctaaagagga
    19681 ctctattgtt aaagttaatt tagaagaaat agatttagaa aagttattgg aagaaatatc
    19741 agaagactat attgacattg ctgagtttca ggaaaaaaga ttcgtgttta attctaaact
    19801 gaagaataaa gttataataa cagataaaaa taaattaaga caacttatat taattttcat
    19861 tgataatgcc tttaagtata caaaattggg tgatgagata gcattagaat tgaaagaaga
    19921 tatagaggat gaggtaactt tacttataag tgatactggt ataggcataa aaaaagaaga
    19981 gatacctctt atatttgata gattttttag aagtgaaaat gtaagaaata aagatttaga
    20041 aggttctgga ataggacttt caatagctcg catgattagt ttaaacttat ctattgatat
    20101 aaatgtaact tctgatgtag atattggaac tacatttgaa ttgtcaatac caaaaaagtt
    20161 aaaataataa aaatataaaa aattgttttt agaaatgaag aatgggtata ctaattagta
    20221 taaaatataa aaagacctta taaaagtaaa tttatattta taaatttcat agtataatta
    20281 tatagggata ataaagttta ataggaggat ttaaaaatgg caaaagttat aaatacatct
    20341 gaatttagaa gtagtgttga aggtagtaag ggagtagttg tagttgattt ctttgcaact
    20401 tggtgtggac cttgtaacat gttgggacct gtatttgcag aattaggtga agagatgaag
    20461 gataaagcta gatttgtaaa agttgatata gatgagagtt tagaaatagc tcaacaattc
    20521 aatgtatcta cagtaccaac tatgattata tttaaagatg gaaaaccagt agaaacttta
    20581 attggattca tgccaaagaa caaaattgaa atgcaagtaa aatcatattt ataaaaaatg
    20641 ggtgagtatt atgagatatg atatagctat aatcggcagt ggtccagctg gattgtctgc
    20701 tgctataaat gcaaaaataa gaaataaaac aattatcatg tttggtaatg ataatttaag
    20761 taataagctt gttaaagctc cttcaataga taattattta ggtttttatg atataagtgg
    20821 tgatgaatta aaagacaagt ttaaatcaca tatagatagt atggatattt caattgaaaa
    20881 taaaagaata aataatattt atgctatggg agaatacttt acaataatgt ctggaaatga
    20941 tatgtatgaa gctactactg taatccttgc aactggggta gagtatacta gaccaatcaa
    21001 gggtgaagaa gaatttctag gaagaggtgt gggctactgt gctacatgtg atgcaccact
    21061 ttatagaaat aaaaaggtag cagttatagg atataatgaa gaatctaaag aagaagcaaa
    21121 ttttttaagt gaactcactt caaagactta ttttatacct atgtacaaaa aagataatct
    21181 tatgagaagt tcagataacc tagatgattc tattgaagtt atacatgaca gaccagtaca
    21241 gatagatgga gataaacttg taaacaaagt atcttttaaa gaaaaccaca ttgaagttga
    21301 tggagtattc gttataaaag atagtacggc tccaagtgca ttggttcctg gaatagagat
    21361 tgatggcatt catattaaag ttgacaataa tatgaagact agtatagatg gatgctttgc
    21421 tgctggagat tgtgttggaa aaccctattc ttatataaaa gcagctggtc aagggcaaat
    21481 agcagcttta aatgctgttt actatttaga taaattaaag agggcttaat atttatattg
    21541 attaactttt taaagatatt tataaaaaac tgtcttgaaa taattttatt atttcaagac
    21601 agttttttat ttttaagtta ttaataaaag tattttaaaa tctatatgta attactttta
    21661 ttaataaaac tcaaagttat attagtaaaa attggaatta tttataatat actccaaaat
    21721 ttaaaaataa tggttgaaaa atctaattaa gagtactata atttaattaa gtaattactt
    21781 aatcaaaatg aggtacttat ggaaaacttg gttaaaatat ttaaagcatt gagtgatgaa
    21841 actagactta acatacttat attagtatcc aagagaaata tatgtcaaaa ggggatttct
    21901 aaatatctag ggatttcaga ttctgctgtt tcacaacata taaaaatatt aaaagatgtt
    21961 gggataataa caggatataa agaaggatac tatgttttat atcatattaa taaagaatca
    22021 tttaatatat gtgtagattt tataaattct atgttaagta attctagtga aagctttata
    22081 gatgtatttg atgtaaatac aatacatcta ggatgcagta aagaatgtaa atctataaaa
    22141 aaatgttgta agagaaggga gaaataataa tgaaagtatg tataccagta gaggagaata
    22201 aaggattgga tagtaaacca tatggacatt ttggttctgc tccaattttt gttgtgtgtg
    22261 atttagaaag tggagaagtt aaatctttag ataatggaga tttagatcat gaacatggaa
    22321 aatgtcaacc attaaaagca ttgtcaggga cagctgtaga tgcagtagtt gttggaggaa
    22381 taggacaagg agctataatt aaattaaatg gaatgggaat aaaagtttac agagcagaag
    22441 gtgatactat aagtgctaat ttagacttac ttaaaaatgg aaaattagta gaatttccat
    22501 cagaccatac ttgctcacat gacggatgtg gacatcatta aaaaaaaaca gctgatgaaa
    22561 tatatacttc atcagctatt ttttctttta ataaatacga ttttattctt ttaaaaccaa
    22621 aatttagatt tttatgtttt ttgtagtatc cttaataata tttcaagttt acaagtttac
    22681 tacttttaga ttttttttgt atgtttttct atatagtcaa tatcatttaa tatgtcattg
    22741 agttctttat taagtgtttt taaatcatca ccatctacat tgtagtttaa aaatagttcc
    22801 tctacattat caatgataga attgactttt ctagtaactt caacaaatgt cttaaagtta
    22861 ctactatttt tagcatttag aaattttttt aaatcctttg atataaatga tactatttca
    22921 tattcatcat taaatagacc tctaccaata ggatatggtt caattctctg taaaaaatat
    22981 tggtctttag cattaatatt ataagtataa gatatttccc aaccgtctcc taaatcaaac
    23041 ttgataaaat ataatgtact acttactttt gatattcttg tggcaccaag ctgtcttaaa
    23101 agaacttcaa tcgaatcacc ttgaacagta ttaatattca tatatacaca tcccctttag
    23161 tattattata ctatattttt taaaatttta taattaaata aacagtagat ataataatag
    23221 atataatcat aagtggaaaa cctattttga aatactcctt aaaagagata ggatgaccgt
    23281 gtttattacc tatacctgct agtacaacat tagcagatgc tcctattagt gttccatttc
    23341 ctccaagaca agctccaaga gatgttgccc accatagtgg cattacatca ataccttcag
    23401 cttgcatagt caaaataaga ggaattagtg ttgcaacaaa tggaatatta tctaagaaag
    23461 aagagactat agctgacaac cataatatca acaacattgt aaatacaaga tgtccttctg
    23521 taagtccaat caatgcttga gccaatttgt ttattatccc aacttctact aatccaccaa
    23581 ctactacaaa taatcccata aagaataaaa ttgtagacca ttcaatatct gccataattt
    23641 catctacatc ttgttttcct attaaaagca ttatagatgc tcctgtcagt gctacaacag
    23701 aagaatctat gtggattgta ctgtgaaaca taaaaccaaa aagtatgaat gctattaata
    23761 taaggctttt tataagtaga ggtttatctt taacagattt tttttcatct agttttaata
    23821 ttgcattttt agctctttca ttcacaacaa gttcttttcc ataaataaat ctaaagcata
    23881 ttatagttat agcaagtatt actataacag caggacctaa atttattaca aaatccataa
    23941 aactaagatt ggcagcacta ccaatcataa tatttggagg gtctcctata agagtagctg
    24001 ttcctcctat atttgaagct aaaatctgtg ttattaaaaa tggaactgga ttaagtccta
    24061 atatttgtgt aataactata gtcattggtc caataagtaa gacggttgta acattatcta
    24121 atacagctga taaaatagct gttataatag caaaacaaat cattatcttc catgggtcac
    24181 ctttggcttt ctttgcagtc cagatagcta tatattcaaa taaccccgag tttttgacaa
    24241 cagctacaaa tagcatcata ccaactaata caccaatagt attgaaatct atatggctta
    24301 atccttcatc aagtgtaagt atattgaata ttatcattaa tagtgcacca ccaacagctg
    24361 ctacggatct gtttaccttt tctgtaataa tagctgccat aactattaaa aatatacata
    24421 tagctattat ttgttgaaat tccataatat aagtacctcc atttgtatta ttttgtgcct
    24481 aatgctagta ctatatatag tattactttt ttattgtttt ttcaatggat gtatgaaagt
    24541 atattattta acaaagtttt tggaaaattg acagaattta aagaaaattt ttgttattta
    24601 aataaatttt aaaattattc cattgataat aatattaaac gacaaacgaa aaaatatacc
    24661 ctttaaac
//
LOCUS       DAYAKB010000052        23443 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.052, whole genome shotgun sequence.
ACCESSION   DAYAKB010000052 DAYAKB010000000
VERSION     DAYAKB010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23443
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.052"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            119..1030
                     /locus_tag="ACGI3L_002519"
     CDS             119..1030
                     /locus_tag="ACGI3L_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198219.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDYDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDE
                     ELYNINEQESEYNYNEKNTKTRAKKKR"
     gene            1145..1325
                     /gene="ssrS"
                     /locus_tag="ACGI3L_002520"
     ncRNA           1145..1325
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACGI3L_002520"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            1508..2725
                     /gene="cdeC"
                     /locus_tag="ACGI3L_002521"
     CDS             1508..2725
                     /gene="cdeC"
                     /locus_tag="ACGI3L_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HFG9198220.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(2826..4148)
                     /locus_tag="ACGI3L_002522"
     CDS             complement(2826..4148)
                     /locus_tag="ACGI3L_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFG9198221.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(4199..4993)
                     /locus_tag="ACGI3L_002523"
     CDS             complement(4199..4993)
                     /locus_tag="ACGI3L_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HFG9198222.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            5103..6548
                     /locus_tag="ACGI3L_002524"
     CDS             5103..6548
                     /locus_tag="ACGI3L_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9198223.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            6577..6786
                     /locus_tag="ACGI3L_002525"
     CDS             6577..6786
                     /locus_tag="ACGI3L_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HFG9198224.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            6806..8200
                     /locus_tag="ACGI3L_002526"
     CDS             6806..8200
                     /locus_tag="ACGI3L_002526"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFG9198225.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVIWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            8439..9191
                     /locus_tag="ACGI3L_002527"
     CDS             8439..9191
                     /locus_tag="ACGI3L_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198226.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            9217..9630
                     /locus_tag="ACGI3L_002528"
     CDS             9217..9630
                     /locus_tag="ACGI3L_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9198227.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            9634..10377
                     /locus_tag="ACGI3L_002529"
     CDS             9634..10377
                     /locus_tag="ACGI3L_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA/SgcQ family protein"
                     /protein_id="HFG9198228.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            10377..10847
                     /locus_tag="ACGI3L_002530"
     CDS             10377..10847
                     /locus_tag="ACGI3L_002530"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9198229.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            10864..11622
                     /locus_tag="ACGI3L_002531"
     CDS             10864..11622
                     /locus_tag="ACGI3L_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9198230.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            11606..12448
                     /locus_tag="ACGI3L_002532"
     CDS             11606..12448
                     /locus_tag="ACGI3L_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9198231.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(12608..13513)
                     /locus_tag="ACGI3L_002533"
     CDS             complement(12608..13513)
                     /locus_tag="ACGI3L_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism-associated LysR family
                     transcriptional regulator"
                     /protein_id="HFG9198232.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            13875..14609
                     /locus_tag="ACGI3L_002534"
     CDS             13875..14609
                     /locus_tag="ACGI3L_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198233.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            14820..16001
                     /locus_tag="ACGI3L_002535"
     CDS             14820..16001
                     /locus_tag="ACGI3L_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HFG9198234.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVISDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            15985..16557
                     /gene="mobB"
                     /locus_tag="ACGI3L_002536"
     CDS             15985..16557
                     /gene="mobB"
                     /locus_tag="ACGI3L_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HFG9198235.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            16676..16951
                     /locus_tag="ACGI3L_002537"
     CDS             16676..16951
                     /locus_tag="ACGI3L_002537"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9198236.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            17194..18894
                     /locus_tag="ACGI3L_002538"
     CDS             17194..18894
                     /locus_tag="ACGI3L_002538"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198237.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            19257..20444
                     /locus_tag="ACGI3L_002539"
     CDS             19257..20444
                     /locus_tag="ACGI3L_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198238.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            20504..21667
                     /locus_tag="ACGI3L_002540"
     CDS             20504..21667
                     /locus_tag="ACGI3L_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9198239.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGDNPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            21818..22621
                     /gene="zupT"
                     /locus_tag="ACGI3L_002541"
     CDS             21818..22621
                     /gene="zupT"
                     /locus_tag="ACGI3L_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HFG9198240.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            22725..23276
                     /locus_tag="ACGI3L_002542"
     CDS             22725..23276
                     /locus_tag="ACGI3L_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HFG9198241.1"
                     /translation="MEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGIFYF
                     HKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYKDIP
                     PKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVLQII
                     LLILYAVQLYRRLMYYLRLKKFK"
BASE COUNT         9197 a         2513 c         4156 g         7577 t
ORIGIN      
        1 aatataaata aaaattctta tagataatat atatgcactg agctttaaaa atggaacatt
       61 aaaatatgaa aaacatactt taatataggg caattatata atataagggg gaattgtctt
      121 gaataactta ctatttttga ttggagtgat tgcattgagt aatggtaata tctctatatt
      181 tgatgataaa aataaatcaa aaggaaataa tagagttaga aaaaacaaaa aaaatgcaaa
      241 tgataaactt tcacagtcta cacatggcaa tttaaggttt gatgcaaatg atataaaaag
      301 aggtttaagg ctcatggatt taagtgaaga agatttagaa atgggaatgg aaataataac
      361 aagaactaaa aaatacatgt caagagatga aagaaaaata ctaataaaaa tagaaagtgt
      421 tttagattta gttagaggaa taaaaaaatt aaataatata gatatggtag atacagaaga
      481 tgaaacggat tttttcagaa aaatggatag tgatgataaa aagaatatga tgataaagga
      541 aattatagat gtattcccag aaaaaagaaa aaattcagtt gaaaaagcta taggaatgaa
      601 aaagaagata gatttatttg cagaattatt tttaccagat gactttggtg aaggtggatt
      661 tagtttgagc tctttggcaa atataaacaa tcttggtagt atgaataatc tcaaattgtt
      721 aggaagtctt ttaagaggtg atgatagtaa taatgatgat gaagacaata atgatgagtt
      781 aaattatgaa gacgaagaat tagattgtga agacaaagaa ttggatgatg attatgatga
      841 gttaacagac gaaggtgaaa tggaggataa tgaagatgaa ttagtagaag ataagaacac
      901 aggctatgaa aatatagaaa atgatgaaga tatagtatat gatgaggaac tatacaacat
      961 taatgagcaa gaatccgaat acaattataa tgaaaaaaat actaaaacta gagctaagaa
     1021 aaaacgataa ttaactaaat acataaagaa aaaaggaaga aaaagtaatg atagaataag
     1081 attatctcaa ttactatata aaaccacttt aaaaaattca aaatttatta tataataata
     1141 atatgaaatc ctgaaacata cgataaggct tttttaaatt caacctacaa atgaaatacg
     1201 ggagaccgtg tctggtaaat tataacatgc ctagttagtt tggacgttaa aggttactgg
     1261 caagtcaccc acctgggagt gcctagggtg tgaatttact tagccaccgg tgtttcggga
     1321 caaaaaaagt gctactattt caaatagtag tacttttttt attaatatgc atttttctac
     1381 taaatacgcc taattattga taaattcaaa aagcaagtaa caattaagat tataaaagca
     1441 tagtattaat taggcttcaa aaagccaaag acttaataag aatcgcttac agggagggca
     1501 atgaaaaatg caagattata aaaaaaataa aagaagaatg atgaatcagc caatgtctac
     1561 aatgaatgaa gaagaagtgt atacagatga aataaattca gaagacatga gaggttttaa
     1621 aaaatcacac catcataatg gatgtaatac tgataataag tgtgagtgcc atgatgattg
     1681 caatccatgc aacccatgta atccatgtaa acctaaccca tgcaatccat gcaaacctaa
     1741 tccatgtgat gacaattgtg gatgccatga caattgtaaa tgtgattgtg aaccatgtga
     1801 aatggattca gatgaatgtt ttgaaaacaa atgtggacca gaatgctgta atcctatatc
     1861 tccaagaaac ttctctgtat caaatgcagt gccatttgca atagaggcta atagaatatt
     1921 tgatactatg caattccaaa catttacaga tgcaacagga ccaaatggag agccattaac
     1981 ttttgaaaca gaagtagtag aagtatttgg ttcagttcca agtgcaggtc aagcaagtgt
     2041 aactatagaa aaaatatgct taagtaatga tggaatcgtt atagacacag gaatgacaac
     2101 tttagaagat ttcgatttag acccattagg agatatagta ggaagaaact gtgaaacaac
     2161 ttttgaattt gcagtttgtg gagaaagaaa cgctgagtgc tgtagacaag gaaaaggcaa
     2221 atcagtagct tataaacaaa gaggattaac tgtagcagtt cgtaatttag tactagagct
     2281 aagaggtaga tgtggatgta cagagttcgt tgcattagct ttcccagcag ttagagcagg
     2341 aggtggatgt aagagaagag ttgattatgt agaatttact tttaacacac tttcagcacc
     2401 aatatgcttg ccagctgacg gaagagctgt tactttaaga caagaatatc aaactaactt
     2461 aactgtagat tgtataggaa aatctatatt aaaattagaa tgcaacgaat gttgtgaacc
     2521 tttctatgaa ttaattatac caaatgatat agatttagta ctttgcttac aagaaacagt
     2581 tagcacatta ataagtgaac aaatagtagt tttagcatca ccaaatccaa tccaaccaag
     2641 acttgttgat actttctcta aagtatgtga tttttcgcaa tgtggaccta atcatggaag
     2701 tggaaagcca agttgccaca gatagatagg taagatatat agacagttta aattataaat
     2761 aaaaatcatc taaggaaggc taccaaagtg tataatttac attggtagcc ttcacgtttt
     2821 tataactagc gtatagattt tagtgattta aaaagcacta tagtatgtaa tagacaagta
     2881 aagattgata ctatcgtcat tgtgtatatg tatgcataaa tattaagtcc tggaattgga
     2941 agaaatacat ataaagctat tagttgaatt aacatgccag taatagtatt tatacttgaa
     3001 gctaattctt ttcttattga atgtaaaatg ccagatagag tttgatttag ggacataaat
     3061 agtggaacta aaaacatagc ttttagatat tctcctgcaa gtgtattttt aaatactaat
     3121 atacataaat cttttccaaa gaaataaaaa aatattgatg atagtatgcc tacaaataaa
     3181 gtaagaagta tggagtattt gattttttta attacactct tacgctttct tagagccatt
     3241 tcttgtgaaa tagttggtat taaatttaca ataagcgctg aaccaacagt aaaaggtaaa
     3301 aatataaaag gcattaccat cccactgaca ataccataca tacttaaaga ttgttgataa
     3361 gtcattcctg ataatgctaa tcttgatggt atcatcatag aacttataga ttgcaaaagt
     3421 atgtttgaca ttctattaca agttatggga atagacattt ttaatgtttc catagaagaa
     3481 ttataaaaat cttttatgct tataatatac ctattgtcaa atgatgaatc tcgccataag
     3541 caaataagca taaatataat attactcaac tcaccgattg atatacctaa tagagctata
     3601 taacaattca tagatttatt atttatgtac ataactagta aaaaaacaaa taatatttta
     3661 ccaatttgtt caatgatttg tccaatagca gggattttta cattctttat gccatagtaa
     3721 tatcctctta gtacgtttga aagagttatt ataactatag caggacaaac agctagtata
     3781 aatagattta atttagcatc ttttaaaaat ttaagtgata aaaaagaact attgaaagat
     3841 gcaactatag atataattag tgctacgaaa aatgatatat ataaagttga tataaataaa
     3901 gcattagtat tgtgtctatc gtttaaagct tttctctttg caactagaca actaagtgca
     3961 gtaggtatac ctgttgttgt aacagctaag caaatcatca aaaagttaaa aatcatatga
     4021 tagataccta aacctgtttc acctagtgct cttgataaga atattttata taaaaaacca
     4081 aatattctta caataaaatt ggatataaat aaaataactg ttgatagtac taaataaggt
     4141 actttcaaaa aaatcacctc cttatctttt aaatatattc acaaggaggt gtaaaaattt
     4201 ataattttat aaattctggt ttcaatttat taaatttaga tacatattta aatcccatat
     4261 tttttagtaa tgaatatatg tagtcaaact cacatgcaac ttgacttata tgatgtgaat
     4321 ctgaacctgt ggttatgatt tcccctccca agtctttata catttgaagt atatacttag
     4381 atggggttag gtctggaaga ttatatctat aacaagaggt atttatctcg atacctttgc
     4441 catcataaat agcttgttta agagtttctt caattatatc agaaaatagt ctatcatcta
     4501 aaatagtgtc ataaggtgca taccttttaa tcaaatctaa atgacctaag acagagtaat
     4561 ctttataatt cttaacaata ttatataaat aaagatagta attttcataa acttcatgtt
     4621 gagttttatc tttaaaataa ttaccaaggt ataagtccat tgtatctata gcatggatag
     4681 aacatattat aaagtccaat ggatattgat gtgcttcctt tttgtatgta tccattaatt
     4741 gagtttgaac tccaaattca attccttttt ttattgatat tttatcttta tatttgcttt
     4801 gaagagtctc taaactctta aaataatctt cgtagacaat tgaaaaagaa tcatcagcat
     4861 atacatcata gtcaacatgg tctgtgaaac aaatttcctc caaaccgagt tcaatagatt
     4921 tttttaccat ttcttccatt gtagattttc cgtctgtaga gaaacttgag tgcatgtgat
     4981 agtcgtaaaa cataaatatt tccccttttt ataaaaattt tggtattata tatacatact
     5041 aaataatatc aaatatacat aaaagcatca ataaaatata aatacaatga gcggtgataa
     5101 atttggaaaa atacagaata gatttaaatg agaaaaaatc aactaaatat atacagatat
     5161 ttaatcatat aaaagaattg ataataaata aagagttagt agaacatgaa aaattgcctc
     5221 caataagaaa actatcaaat tttttacaag taaataacac tactatagtt aaggtatacg
     5281 agcttttaga aaatgaagga tatgtatata aaattatagg gagtggtact tttgtatcaa
     5341 gtttaaattc ttataaaagc ggtatagata acaggaaaaa taagattatt gtgcaaagag
     5401 aagatttaat tcattttgac aatgggaatc catctaatga tatgtttcct atcgattcat
     5461 ttaaaaatgc tgtaaatatg gcattatcta aagatggtag ttcaatattt gaatatgatg
     5521 aaggtcttgg ctctgaagaa ttaagagaaa aaatggtaga gtatctaagt gatggaaata
     5581 taaaaactac taaggaaaat attcaaataa tatcaggtgc tcaacaaggt atagatatag
     5641 tttgtaaagg acttataagt tattcagatg ttgtttttat ggaagaacct tcttacaatg
     5701 gagcaattga agtgtttaaa agtagaggtg caaaaataat atctatacct atgttagatg
     5761 atggaattga tataggtatt ttaaaattaa agttggaaaa aataaaacca agacttatat
     5821 acattatgcc taattttcaa aatccaactg gaatatctta ctcaacatat aaaaaaaaga
     5881 aattgataga attggcagaa gaacatgatt tttatataat agaagatgat tttataagtg
     5941 attttgtttt tgaatcaaag gacaatagaa caattagaag ttatgatgat aaaaatagag
     6001 tagtatatat aaaaagcttt tcaaaaatac ttatgccagg tcttaggata ggaattgtag
     6061 aaatgccaaa tgagttgtta aaaaaagttt tatgggctaa atattcatca gatatatcaa
     6121 caccaggttt aattcaaaaa tcaatgtatt actatatgaa taattttgat tggaagaatt
     6181 atttgagtca tatagaaaag atatatactg ataagtataa attggcaaaa aacttgatta
     6241 atgacaaatt gagtggtaaa ttaaaagtta gaaaatcttg tggaggaata aacttttttt
     6301 tagaattacc aagaggatat acatctcaag catttacaaa ttttatgtta aacaaaggag
     6361 tgtcaatgct tccagggact tatttttttg acaatctagt ggatgataga ttctttagga
     6421 taaatatagc tcgcccaagc atggaagaac tagaaaaggg aatatctata ataagtgata
     6481 atatagatga gtttttttgt gaatataaaa acaagttaga tataaaaagc aataaattat
     6541 tttattaaat aaatagaggt tttttaggag gaaaaaatgt ttgacaagaa gaaattagat
     6601 aggattaatg aattagcaaa gaaaaataaa gagggaatcc tttctgctga tgaaatcaaa
     6661 gaaagagaaa ttttaaggaa agaatattta gaaaacttta gagcccactt tagatcaaga
     6721 ctagatagtg tcaaagtagt ttcaccagaa gaatatgagc aatacatgaa aaacaataaa
     6781 aattagaact tagtaggagg aaaatatgaa cttaaagtac gaatttaaga atgcttggga
     6841 ttttgaaaga aaagaaaata ctattgaaca aattatgcaa tattctagca attatatgga
     6901 gtttttaagt aagtcaaaga ctgaaagact ttcagtaaaa gaaattataa aattggctaa
     6961 agaaaataac tatatttcaa tagatgaagc tatggaaaaa ggaagcataa gttgtggtga
     7021 taagatttat gttataaata aagagaaggc agtagcactt tttgtaatag gtaaaaatta
     7081 tatagaaaaa ggtatgaaga ttataggaag ccatatagat tcgccaagat tagatttaaa
     7141 accaaatcca ctgtatcaag agagtaatct aggttttttt aagactcatt attatggtgg
     7201 aataaaaaaa taccaatgga cggctattcc acttgcttta catggtatag ttatattaaa
     7261 tgatggaaca aaagtggaca tatctattgg ggaagaagat agtgacccag tattttgtgt
     7321 aactgattta ttgattcatt tggctggaga ccaaatgcaa aagaaactat cagaaggaat
     7381 tagtggagaa gctttaaata tattaattgg aaatatgcct ttagaagatg aagaaaaaga
     7441 acctataaca gcaaatatat taaagatttt aaatgagaaa tacaatatag ttgaagaaga
     7501 tttattaagt gctgaaattg aagtagttcc agctggtaag gctagagatt tagggcttga
     7561 taggtctatg gtgttgggat atgggcatga tgatagggta tgttcatatg ctgctgtaaa
     7621 agctatacta gaaactgaac aaccagaatt tacttcagtt gcattatgtg tagataaaga
     7681 agaaattggt tctaaaggga atacaggtat gcactcaaag ttttttgaaa atactgtggc
     7741 tgaactgatt gctttagaag gagattattg tgatattaaa gtaagaagag ctttagcaaa
     7801 tagtaaggta ttatcagctg atgtttctgc tggatatgac ccaaattttg gagaagcata
     7861 tgaaaagaga aattcggcat atatgggaaa tggagtagtt ttaactaagt atacaggttc
     7921 aagaggaaag agtggatgta atgatgctaa tgctgaattt atgtcagaag taaagagaat
     7981 ttttaataaa ggaaatgtaa tatggcaaac tgctgaactt ggaaaagtag accaaggagg
     8041 aggcggaact atagcccata tattggcaaa tcaaggtgca gaggttatag actgtggtgt
     8101 tggagtttta aatatgcatg caccacatga gattgtctct aaagtagaca tatatgaaat
     8161 gtataaggga tataaggcat tttttaatat aaatttataa gtaaaaatat aaatgtaata
     8221 agtgaataaa ggctgttgta taaacaattt aatctgttgt acaacagtct tatttttatg
     8281 taaaaatagc aatttgtcac actagagaaa ataaaagaaa atactgtcaa attaaaaatt
     8341 atttaaaaaa aattgacaac gatttcatct tgttataata tgtaataaag aacttgttat
     8401 ataatgttat aaaaatgtta catagggagg tgagcaaaat ggatgaaaag agacaaaaaa
     8461 aagaaatgga tttagaagta aattcctttg ttcctttata tcaacaacta tatgacaaca
     8521 taaaaaaaca aatagcatct ggcatatata aaccaggaga taaacttcca tctgaaggag
     8581 acttatgtaa agaatttaat ataagtcgta taactgtgag aaatgcactt aatgaacttg
     8641 taaaagaaga tatattatgt aaaaaacgtg gtaaagggac ttatgtaaca ataccagaga
     8701 gaatagaagc aacatgtgca ggaaatagtt ttactaattc ttgtcatcgt attaatgcaa
     8761 aaccaagtac caaaataatc tctgttttaa taaaaaaagc agataagcaa gtagctgaag
     8821 ctttaagtat tgaactagaa gagaaggtaa tatgtattaa aagacttaga ttaatagatg
     8881 aagtacctgt tatttttgaa gttgactatt ttagaataga ttacatgttt ttattaaaag
     8941 aagaattaga agataaatct ttaatggagg ttatatctaa taatataagc acattaccta
     9001 aacgagtaga aaatatattt gaagtaaaac attcaaacaa agaatattct gaccatctta
     9061 aatgtgcaag taatatgcca ctattgaaag taagacaatc ggtgtataca gaaaataatg
     9121 atgtcttata ttacaatgag caatttataa gaagtgataa gtacaaatat gcagtatcag
     9181 cagaaatata atctataatt tagtaggagg atgagtatga aaaagataat attagcatct
     9241 catggagact tttcaaaagg gcttttaaat gcagtaaaaa tgatagtagg agatttagca
     9301 gattgtgtca gttcgtatgg tttgtaccct ggacaaagtg cttcagattt tgctttagaa
     9361 ttagaaaaaa caatatcaga agataaagaa tgtgaatata taattttatc tgacttatat
     9421 ggagcaagtg tatgtacagc aatgttaaga ttaactaatc tacataatgt taggttattt
     9481 tctggaatga atttgaatat ggtattagaa cttcttacaa ggttttctga tgaattaaca
     9541 gttgaagata tagaccaatt agtggaagaa tctagaagag gaatacaaag cgtgacatta
     9601 caaattaaag aagaagaaga ggtattttag tttatgaaaa aaaagggaat attatcagta
     9661 tttaaaagta aaaaaccaat tatagcaatg atacacttaa aaggagatac tccagaagat
     9721 atctttgaaa gagctaaaaa agagattaca atctttgaag aaaatggtgt agatggaata
     9781 atgttagaaa attactatgg taattattat gatttagaaa gaatacttga atatgtatca
     9841 aaagctaatt tatcaatacc atatggagta aactgtttaa atgttgatac tatgggattt
     9901 gaactggcaa caaaatataa tgctagttat atacaggttg attctgtagt aggtcatgtt
     9961 aaacctagag atgaagctac tttagaagag ttttttaaat tacaacgttc aaaatgtcca
    10021 gcgtatttaa ttggaggcgt acgttttaaa tatcagccag tattatcaga aaatgatgtt
    10081 gaagaagatt taaaaatagg aatgacaaga tgtgatgcta tagcagttac agaaaatgct
    10141 acaggtcaag aaacatcaat ggaaaaaata gaactgtttc gtaaaaattt aggagacttc
    10201 ccattggtta tagctgctgg agttacatta gaaaatgcaa aaaaacagct taaattagga
    10261 gatatggcaa taataggaag ttactttaaa gataattaca aagattttgg ggatgttagt
    10321 gtagaacacg taaaaacatt catggatgaa atcaaaaaaa ttagggagga attataatga
    10381 ttaaattagt aagagtagac cacagactta tacatggaca agtagcattt acatggacaa
    10441 agtttttaag tacagactgt atattgatag caagtgatga cttattaaaa gatgaattaa
    10501 gaatggcagg acttaaaatg gctaaaccat ctaatgttaa gttagtaatg aaaagcatag
    10561 cagattctat aaaagcactt aactcaggtg ttactgataa atacaactta ttgatacttt
    10621 gtgaatctgt agaagatgtt tacagacttg ctaaagaggt aaaagctatt aaatctataa
    10681 accttggtgg aacaaaatca gatgataatc gtgaaaatat atctaaagca gtgcatgtat
    10741 caaaagatga tataaagatg attaaagagt tagattcaga aggcgtaaat gtatttgtac
    10801 aattagttcc tgatgatgat gctacaaatg taatgaaatt aatataattt tagggggatg
    10861 aaaatggaat ttacacaagt tattttgata actctaattg cattctttgc atatatgcat
    10921 agttttgtag gttctacaat gcataataga cctatagttg ttgcaccact tgttggttta
    10981 gcactaggta atcttcatac aggtatagta ataggttcaa cattagaatt agtatttatg
    11041 ggtgcatttc ctgttggggc aagtaatcct cctgattttg tgtctggttc tattattgcc
    11101 acagcgtttg taatattaac gggtcaagat gtatcagcag cagttgtact tgcagttcct
    11161 atagcaactc tagtattgct tatagataac ttcttaatga cagtagtact tacatgggga
    11221 gctcatattg ctgaccgtta tgcagaagag gggaatattg aaggcgtaga acgtgtgcaa
    11281 ttattatttg gtataggaaa taaattaata ttagcaataa tagtaggtat aggattttca
    11341 ttaggtgttc cagtaataga aaaaatactt tcatttatac catcatatgt aactcatgga
    11401 atggatgttg cagcaggcgt gattccagca ataggttttg ccatgttagc tagaatgatg
    11461 cttaataaga aaacagtagc atttttatta ttaggattta tattggttgc ttacctaaac
    11521 ataacagtaa caggagttgc attgtttgga ttagcaatag ctttaatata tgttaacttt
    11581 gtaggagaga aggaggtaat agtagatgac aacgagttct aagaaattag agacaatttc
    11641 accagatagt aaaataacga ggaaagactt ttggaaatgt tttagaaggt cattgacatt
    11701 agattcatct tggaactacg aacgtatgca aaatatagca tatgcataca tgatggcacc
    11761 aataatccgt agattatata aagatgataa agaaaagaaa tctaaggctt taaaaagaca
    11821 tttagaattt atgtcagtta ctcctcatat aagtactctt ttggtaggta tatctggagc
    11881 tatggaagaa gaaaatgcaa agaataaaga atttgatgct aatagtataa atgctgttaa
    11941 atcaagttta atgggtccag tttctgggat aggagattca tttttctggg gaacattaaa
    12001 gcttatagca gctggggttg gtatagcttt agcttctcag ggtaacataa tgggaccgat
    12061 tttattcctt ttaataataa atgttcctca ttttattata cgctatatat gtctagataa
    12121 aggatttaag tatggaactc aattctttaa agatgtgagt ggttcaagta tagtttcaaa
    12181 agttatggaa gcagcttcaa tgttagggct tatggtaatt ggaggtatga ctgcatctaa
    12241 tgtaatgtta aaacttagtg ttaatgtagg tagtggagaa tgggcagagc ctattcaaac
    12301 ttacttagac caaataatgc catgtatgct tccagctatg atattcggta ttatgtattg
    12361 gttattagga aaaaaggtaa agacaactac gatattaatt tcagttatga ttatttgtat
    12421 agtattggct gctattggag tagtataaat aaaaaaatcc caagttcatt tgaacgaggg
    12481 attttttgac taaattaaat aaaaaagaaa gatggttcat aataatttat aagcatttat
    12541 gtgatagtta taattagctt attaattagt tataaactca aaattaagca ctactttatt
    12601 aaagttatta tattataatt tcgaaatact cacataatct gtttagaaat ttatcttcta
    12661 atggggaaaa agttttcttt ttagagtaaa tgaagaaaaa ctttctagta aaatcaacat
    12721 cctttatttt ataacatttt attttacctg cattgagata atcgatagct gaaatgtacg
    12781 atataaagga cactccaaga cctaatctaa ccatttcctt aatagcctca tttgattcta
    12841 catgagcgat tacatttaat ttacttactg gaaagttatt tttactaagt gtgtttagta
    12901 ttaagtttct tgtacctgac ccttcttttc tcataataaa atttagataa gccaattctc
    12961 ctatatcgat acaattattt ttattatcaa ttttaaaatc tgaaggagtg ataagaacaa
    13021 gttcatcatc taataagtct aggtactcta tttgaggatt attgatttta gaaccaacta
    13081 atccaaagct tattcgttca tttaaaattt ctgatatagc atattgagaa tcataatggc
    13141 ttatggaaaa ttttacatct ggataactca tagaaaaact cttcataaaa tcaggtaaaa
    13201 tataagtttc aggtatggaa ctacatgcta tatctataat accttctatt tttcctgaat
    13261 attcttttat atcataaatt gcacgtttgc aattattcaa tatatatata gcatgttcat
    13321 aaagaatttc accagatttt gtgagtgtaa taactttgtt gcttctattt ataagaacag
    13381 tttctagctc tctctctaaa ttctgtatgt gtgcgcttac agtaggttga gttaaaaaaa
    13441 gttctcttgc agcctttgaa aaactctgat gttttgcaac agcaacaaat acttcaagtt
    13501 gtttaaaatc cattatttaa tcctccttaa attatctaaa actattataa catatttgat
    13561 aaattaatag tcaaaggtga tttttaaaat agaaaacctt taaatattca tggagttttt
    13621 gattgtttag gaataatttg gtataatgtt gtaaggtact tacaataaaa atatcgtaaa
    13681 ttgaattttc aaaattcaac tttaaagtgt tttttattac agaaaaatta caattagctt
    13741 cttaatctta ttaaattcaa ataaatatta tataattatt ttataatata ataaatataa
    13801 ttattgaaaa aagagataac tgtaaattga gatatagata aatactataa aatttaagaa
    13861 aggaggattg atttatgaag ttaaaaaggt cattagtttg tgtaactatt ttaggtatta
    13921 tacttgttgg atgtcataaa gaaaatacta aagagaaaaa tcaagtagca agtaaagcaa
    13981 cacagcaaaa aactatgaca aaagttcaaa atgatgttaa tgaaattatg aataaagatt
    14041 ataagtacat tataaagaat atgggtatac cttataatac attttattat ataaaaccta
    14101 aagttttaaa agaatcaaat acaatgcaag atataaatac atcaagttat atgacattag
    14161 tttatccaaa atatactgga aatgatgaac tagatggaag tgctttatat gttgatatta
    14221 acgaaaataa agttgtcaat gttgaaacca attctttctc atcacaaggt atatcagtca
    14281 ttgatgctga atctagtata gtgattgaaa aaagtgacca tgaaaaatcg gctgtatcac
    14341 tagaaaattt tagacatatt gacctgggag agtatgttgg tgttgaagat tccagaataa
    14401 atgaaattgt aggagatgcg aattatgatt taacagcata taatcatgaa ggcagtaaag
    14461 tagttaagag ttatagattg aaagaagata acaaaatatt aaaaaaagag gtacttacaa
    14521 taagtattgt ggataacaaa ataaaatcta taaaaactat tgaaagtgat aaaattgtaa
    14581 aaataataaa aggaacttta ttagaataaa atattctaaa gcatatgatg ctgtttcaag
    14641 atagaaggaa atttctagct gggaacagtt tttttattag atttataaaa tttgaactgc
    14701 acttatagat aactattagt tataattaaa tataagataa aagtatttcc aacttttata
    14761 atctataata tattacatag aaatatctta aataaaaaat atattgggga gtatttaaaa
    14821 tgatagaatt agaagatgcc ataaaaatta ttgaaaaaaa tgttttacca ataaacaggg
    14881 tcaagatagt aaatcttata gatgcagtaa ataaggtagt tgcagaagat atatattcaa
    14941 caattgatag tcctccattt gataggtcac cctatgatgg ttatgcatat aatgcaaatt
    15001 ctgaaaatag aaatttaaag gttataggga ctttgtatgc aggagatgta tttaataggg
    15061 tattaaataa aaatgaagca gtgaagataa tgactggtgg aaagatacca cagggtgcaa
    15121 attgtgtaat aaaaaaagaa gatgtaacag ttataagtga tatgataact ttaaatataa
    15181 aattaaagga atacgataat tacatattta agggtgagga tataaaaaag gggcaattga
    15241 ttattaataa aaatcagaat ataggatatg atggtattgg agtattagca agtcttggaa
    15301 tatccaaagt aactgtttat gatgatttaa aagttggaat tttgaataca ggtacagaac
    15361 tacaagatat aaatgagact ttagagaatg gtaaaatata cgatagtaat agatatacct
    15421 tatattcaag attattaaaa cttggaatac aagcagatac aatatgcaat tgttctgatg
    15481 atatattgga gttagaaaaa aaggtaaaga atatgttaca gagtgtagat tttttaatta
    15541 ccacaggtgg tgtttctgtt ggagataaag atttaattcc agatgtattc aaaaaaatag
    15601 gggcaacaga attattttgg aagataaaca ttaaacctgg tggagcttgt tatgtaggta
    15661 cattgggaga aaagctatta tttggtcttt ctggtaatcc acatgcagca atagtggtat
    15721 ttgataatgt gatagttcct gttattgagt atttaacata taagaaggga acacatcata
    15781 taaaagctat atttaaagga gaatttaata aactttcaaa taaagataga tttgtaagtg
    15841 gaaaactata tacaagtgaa ggtaaattgt atgtagagct aaatgataag aaagatgcaa
    15901 aagctagatt atctgcaact ctaagaagta attgtatgat taagattaaa aagaatgaga
    15961 caataaaaga aaatcaatta gtggatgttg ttattagata gttttatgaa aggacacaat
    16021 tttatgtata atatattgtc agttgtctca tattcaggag taggtaaaac tacattgatt
    16081 gaaggcataa taaaagaatt aaataaaaaa gggtatcgtg ttggagttat taaacatacc
    16141 tgtcatgatt ttgatatgga tgaggaagga aaagatactt ataaacatag aaaatctggg
    16201 gcgagaaaag tctgtataat atcagataaa cgagtagcat atattgaaga actaaaagag
    16261 aagaatccat tatataaaat gattcaatta tatgaagata tggacttgat tatcatagaa
    16321 ggatataaaa attatagatt taaaagattg gaagtaacta gaaaaggtaa gtatgaggat
    16381 attttatcta ataagtctga tttgataggt attgtcagtg atatagaata taaattgaat
    16441 attgaacagt ttaatttaaa tgattataaa aatatatcaa agtacataga gtcttgtata
    16501 aaaaatgaaa ttttaagtat aagcaatgtt gaaataaaaa acatattaaa agaataattt
    16561 taagatgttc ttcttatata aaatgatata attatttata taaataaaga tataagaaat
    16621 ttatcaattt tattttgagt tataaaatat taaagaaatt gtaggaggac aatatatgaa
    16681 aaaaatatta gtagcctgtg gagcaggaat cgcaacatca acaatagttt gtgacagagt
    16741 agaaagattg gttaaagaaa ataatataca agcagaagtt gagcaatgta aaattgctga
    16801 atgttcaaca aaacaagaag gtgctgattt aatcgtatct actactatac taccaacaac
    16861 ttatgatata cctacaataa aggcaacagg atatataaca ggtataaata caacagcatt
    16921 agataaaaag atattaaatg cattgaagta gttttgtatt tataaaaaaa atttagtatt
    16981 aaatatagag ttgtatcttt ataaaatttt aaatatagag atatagctct ttttatgttg
    17041 tttcaagtat acaactatat gatataaatc ttcaatttta tgaaaaagat tgttattact
    17101 ttgtaagttt ataaaagatt taaagttatt gttatgttat actaatttat gggtattttt
    17161 tagaagtact aataaaggag ggatttaata cttatgataa aacaatttgt caaatattat
    17221 aagccatata agaaaatttt tacactagac cttatagcag cttttctatt ttccttatgt
    17281 gatttagttt atcctatgat aactagaaat ataatggatg acgttgttcc aaataaaaac
    17341 ttaagaatgt tagtagtttt tgcagtagca cttatactta tatttatagc aaaagcaggg
    17401 cttaactatt ttatgcagta ttggggacat gttattggtg tagatatgca agctgatatg
    17461 agaaatgagg tatttacaca cttacaaaga cttccaaata cgtattttga taataacaaa
    17521 tctggagtaa ctatgtctag aatagtaaat gatttaatgg atataacaga acttgcacat
    17581 catgggcctg aagatttatt catttctata gtaatgttgg ttggttcatt ctttatactt
    17641 atagatataa atattcctct tacgcttata atatttgcta tattaccgtt tataatttgg
    17701 tttgcaatag ctaaaaaaga taagatgaat attgctttta tgaagagtag agttactata
    17761 ggtgatgtaa atgctacttt agaaaatagt atagcaggta tgaaggtaac taagtctttt
    17821 tgtactgaga aagaagagtt aaataagttt gtaagaagca ataaattatt tagaagagca
    17881 agacaagatt cttataaggt aatggcagaa tattactctg gtatgaattt atacatggat
    17941 atcttagagt gggtagttgt aatagctggt ggttatttta cttatatagg aaagattact
    18001 ttgggtgatt ttgctgctta tatactatat gtaaaaatgt ttatacaacc tatgaaaaaa
    18061 ttaataaact ttacagagca atatcaaaat ggtatgacag gttttaaaag attcatagag
    18121 ataatggaac aagaccatca aaaagaagct aaaaatccta ttgaacttga aaatgtaaaa
    18181 ggtgacattg agatagaaaa tatatctttc acatatgaag ataagactca agttttggat
    18241 aatttaagtt tatctataaa agctggtaag actatagcat tagttggacc ttctggagga
    18301 ggaaagacta cattatgtaa tctattgcca agattttatg aatttgataa gggtgatata
    18361 aaaattgatg gaaagagtat aaaagatgtt agtttaaaat cattgagaaa aaatataggt
    18421 atagttcaac aagatgtatt tttatttaca ggaactataa gagataatat tctttgtggg
    18481 aaccctaatg ctacagatga agaaatgata gctgctgcta aaaaagctag aatacatgac
    18541 tttgtagaga ctttgccaga tggatatgat acttatatag gagaaagagg cgtaaaatta
    18601 tcaggtgggc aaaaacaaag aatttcaatt tcaagaatct ttttaaagaa tcctccaata
    18661 ataatattgg atgaggctac atctgcttta gacaatgtaa cagaaagaga aattcaagag
    18721 tctttagagg aattaagtaa agatagaaca aatttagttg ttgcacatag attgactact
    18781 ataaaaaatg ctgatgaaat catagtattg acggataaag gaattgaaga aagaggtact
    18841 catgaagagc tagtaaacaa aaatggagta tatagtaggt tacacaataa ctagtataca
    18901 aattttacac catagctaac atacacatta aacttacaaa cataggatat attaagattc
    18961 ataaagacaa ttcattttat atttataaga tgttttatga ataaaatgta tcctatgttt
    19021 tattttttgc aaattacatt taattctctt tgtaagaata gagttaaata gccaatggtc
    19081 gggataacgt ttttacaaaa agaataattt agaaaactaa ctttaattta tggaatttat
    19141 cgaattttat gaaaaaaatc gaattttgac ttgaaatgtt tttcaaaagt agtaaaataa
    19201 tggataacta tacatacatt ttataaaaat atatttatta tgagggggga ttttgtatgg
    19261 aggcaataac agctttttgt ctagttttag tatcactgac gataggagat atagtttcag
    19321 caaaaactaa agcttttgtt ccgtcggttt ttgtatcagc aattatattt atagtaggat
    19381 tttggacttt tttcccagaa aatattgtgg acttagccgc tttaggaaca ccattagctc
    19441 aattaggtat gcttttgtta ataactcata tgggaactat gatgagtatt aaggaattag
    19501 caggtcaatg gaaaacaata gtaatagcct tggcaggaat agtaggaata tgtgtaggtg
    19561 ctttggcatt agggacagta gtatttggat gggatacagc agtaatagct acacctcctc
    19621 ttactggagg gctagttgca tctataatga tggcagatgc tgctacagca aaaggtcttg
    19681 caagtttatc agtacttgca attttgatgt atgttgcaca aggatttgcg ggttatccta
    19741 ttacagcatt aatgcttaaa aaagaaggaa aaagactttt atcagacttt agaagtggaa
    19801 aagtaactgt aaatacagat gaagaaaaag ttaaggattt acctgaacaa aaaagcagat
    19861 ttaagataat accagactta ccagaaaaat atgatacgac atatatgata atacttagat
    19921 taggatttgt agcatggtta gcagtacaat ttacaaatct tacaaatgaa gttgtatcaa
    19981 gatatgttat atgtttaata tttggtgtaa tagcatcaga acttggaata gttgatagaa
    20041 aaccacttaa taaatctggt tcatttggat ggttaatgac atcattgatg gcttttatat
    20101 ttgcagggtt agcaaaagct acaccagcaa tgcttgttga aatggcagtt cctcttgtag
    20161 gaatcataat atttggtgta ataggtatgg gaattttctc tattatagta ggtaagcttt
    20221 taggtgaaag taaagaaatg gctttttcag tttcgcttac atcactttat ggttttccac
    20281 caaactatat attaactgaa gaggcagtaa aggctttggc tgaaacacca gaagaaaaag
    20341 aatttttaat ggataaaatg cttccaaaga tgcttgttgg aggatttact acagttacaa
    20401 tagcttctgt agtaatagca ggtatctttg taaatctaat atagtattta attgataaaa
    20461 agtattttaa ataagaagaa tgtgtactac ttggaggtat agaatggata ttaaagaaat
    20521 aacaaagagt tataaagact atgtaattaa gcttagaagg gaatttcatg aaaatcctga
    20581 gaaaagtatg gaagaagtta gaacatcaaa gagagttaaa gaagaacttg ataaaatagg
    20641 gataccatat gtatcagctg gaggtacagg tgtaattgca actataaaag gagataatcc
    20701 aggaaagact gtagcactta ggggtgatat ggatgctcta caagttgttg aatgcactga
    20761 tgtagaatac aaatctaaaa atgaaggact tatgcatgct tgtggtcatg atggtcacac
    20821 atcaatgctt ctaggggcag caaaagtgtt aaatgatatt aaggatagta tcaatggaac
    20881 tgtaaaatta ttttttcagc caggagaaga agttggtaaa ggtgcaagag ctatgattca
    20941 agatggtgct atggaaggtg tagatagtgt gtttggaata catctttgga ctgatgtaga
    21001 atctgggacc atatcggtag aagaaggacc aagaatggct tctgctgatt tctttaaaat
    21061 tactgtaaaa ggtagaggtg gtcatggttc acttcctcat caaggtgttg atgcagtgct
    21121 tgcaagttca gcaatagtta tgaatctaca atctatggtt agtagagaag taagtcctct
    21181 ggaaccatta gttgtgagtg ttggagtttt aaattctgga actagattta atgtaattgc
    21241 gagtgaagct atcttagaag gtacaataag gctatttaat ccagagctta gaaagcaaat
    21301 tcctggaatt ttagaacgta tagcaaaatc tacagcagaa gcatatagag cagatgctga
    21361 attagagtat gggtacttaa caccagcagt tataaatgac aaagaatgtt caaagatagc
    21421 tacagatgca gcaattaagc tatttggaga agactgtata acactatttg aaaaagtaac
    21481 aggagcagaa gatttagctg agtttatgaa tatagcacct ggtgcactag catttgtagg
    21541 agctagaaat gagtcaaaag gtgcttgtta tcctcatcat catggatgct ttaatataga
    21601 tgaagatgct ctagaaattg gaactgcttt atatgtgcaa tatgcagtgg atttcttaaa
    21661 taaataattt taatatacta taaagaaaaa gcagagacta agtttatatc tctgcttttt
    21721 tattgtgtat attttttata aatattgact atataaaata tatatgatag cataaagaaa
    21781 atgataatca atatcaatta aaaagaaggt gatttatttg aataatgtaa tatttgcatt
    21841 tttgataaca ttattggctg gtttatctac tggtatagga agttgtatag cattttttgc
    21901 taaaaaaaca aatactaagt ttctttctat aagcttagga ttttctgctg gtgttatgat
    21961 ttatgtttct atgatagaaa tttttcctaa agcacaagat gctttgacaa aatctatggg
    22021 agagaaatta ggaagttggt caactgtaat agcttttttt ataggtatgg ctatcattgc
    22081 tgttattgat aagctaattc cacaagaaga aaatccacat gaaataaaga aaatggagaa
    22141 tatagaagaa aagaatatca aaaaaaataa gtctctttta agaacaggta tatttacagc
    22201 aatggctata gcaattcaca attttcctga aggattagct acatttatat cagctcttga
    22261 tgatgttaca atagctattc cgatagcaat tgcaattgca atacacaata taccagaagg
    22321 tatatctgta tctgtaccag tttattatgc cacaggagat aaaaagaaag ctttttatta
    22381 ttccttttta tctggtatgt ctgagccttt aggagcgatt attggatatg tacttcttag
    22441 aaatttttta aatgatataa ctcttggaat tgtatttgca attgtaggag gaattatggt
    22501 attcatatca ctagatgaat tattgccatc agctagagag tacggggaac atcatttatc
    22561 tatttatgga ttgattgcag gaatgggtgt tatggctatt agtttattac tatttaaata
    22621 acttttaaat atatgattgt aacctaaaat tagtatcaaa atgatataat tatttaaata
    22681 gatttttaag ctatttaaaa atatcatttt ggagaatgag tgctatggaa aagaaaataa
    22741 aattcaaatt tgactggtat agttcacctg ataagataga gaaatggtta gaagatattg
    22801 aagctaaagg atataattta tataagataa ataaatttgg aggaatattt tattttcata
    22861 agggaagtcc aagaaaaata aaatacactg ttgattacta ctatgatgta gagaataatt
    22921 attttgatga acataaatca aatggctgga atcttgtatt taggagtatt ggtagtttta
    22981 tgggtacatc tgcatggtat atatggtcga aagaatacaa agacatacct cctaaattat
    23041 atagtgattc tgataaaaca aataaagtaa agtcaatttt atttatgaat atgtttatat
    23101 tctttatgtt agtagtaata tttatatatt tattgaatat tgaaataaga aatttatata
    23161 gtggttatgg agcatctgta actgctattg tactacagat tatattgttg attttatatg
    23221 cagtacaatt atataggaga ttaatgtatt atttaaggct taaaaagttt aaataaataa
    23281 aagaaggtgt cctaaaatta tttttttaat attttaagac atcttctttt gtcagtaagt
    23341 actgttttta attatagtaa tttctgtctt taaattgaaa tatcaaataa tagttgtatg
    23401 ggattgagta ttgataaaaa taatttaaaa atgttatcct aaa
//
LOCUS       DAYAKB010000053        22956 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.053, whole genome shotgun sequence.
ACCESSION   DAYAKB010000053 DAYAKB010000000
VERSION     DAYAKB010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22956
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.053"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..321
                     /locus_tag="ACGI3L_002543"
     CDS             <1..321
                     /locus_tag="ACGI3L_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9198242.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKS
                     VYKK"
     gene            337..1920
                     /locus_tag="ACGI3L_002544"
     CDS             337..1920
                     /locus_tag="ACGI3L_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9198243.1"
                     /translation="MRILIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1948..3276
                     /gene="ssnA"
                     /locus_tag="ACGI3L_002545"
     CDS             1948..3276
                     /gene="ssnA"
                     /locus_tag="ACGI3L_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HFG9198244.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3475..4827
                     /locus_tag="ACGI3L_002546"
     CDS             3475..4827
                     /locus_tag="ACGI3L_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFG9198245.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            5019..6128
                     /locus_tag="ACGI3L_002547"
     CDS             5019..6128
                     /locus_tag="ACGI3L_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9198246.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6411..7802
                     /gene="hydA"
                     /locus_tag="ACGI3L_002548"
     CDS             6411..7802
                     /gene="hydA"
                     /locus_tag="ACGI3L_002548"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HFG9198247.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7796..10357
                     /gene="xdh"
                     /locus_tag="ACGI3L_002549"
     CDS             7796..10357
                     /gene="xdh"
                     /locus_tag="ACGI3L_002549"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004854 - xanthine dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0046415 - urate metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HFG9198248.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSIPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10509..11855
                     /gene="rpoN"
                     /locus_tag="ACGI3L_002550"
     CDS             10509..11855
                     /gene="rpoN"
                     /locus_tag="ACGI3L_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFG9198249.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            12637..13659
                     /locus_tag="ACGI3L_002551"
     CDS             12637..13659
                     /locus_tag="ACGI3L_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HFG9198250.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            13719..14726
                     /gene="gap"
                     /locus_tag="ACGI3L_002552"
     CDS             13719..14726
                     /gene="gap"
                     /locus_tag="ACGI3L_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFG9198251.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            14948..16150
                     /gene="pgk"
                     /locus_tag="ACGI3L_002553"
     CDS             14948..16150
                     /gene="pgk"
                     /locus_tag="ACGI3L_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFG9198252.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            16176..16919
                     /gene="tpiA"
                     /locus_tag="ACGI3L_002554"
     CDS             16176..16919
                     /gene="tpiA"
                     /locus_tag="ACGI3L_002554"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFG9198253.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            16931..18460
                     /gene="gpmI"
                     /locus_tag="ACGI3L_002555"
     CDS             16931..18460
                     /gene="gpmI"
                     /locus_tag="ACGI3L_002555"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046537 -
                     2,3-bisphosphoglycerate-independent phosphoglycerate
                     mutase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HFG9198254.1"
                     /translation="MKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTLI
                     NASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMDN
                     AKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALEY
                     AKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAIQ
                     NSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDGF
                     KREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAHV
                     TFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVLN
                     FANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPET
                     GKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTILDMMKLEKPEEMTGHSLIS
                     K"
     gene            19048..20340
                     /gene="eno"
                     /locus_tag="ACGI3L_002556"
     CDS             19048..20340
                     /gene="eno"
                     /locus_tag="ACGI3L_002556"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFG9198255.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            20933..21157
                     /gene="secG"
                     /locus_tag="ACGI3L_002557"
     CDS             20933..21157
                     /gene="secG"
                     /locus_tag="ACGI3L_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFG9198256.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(21541..22479)
                     /locus_tag="ACGI3L_002558"
     CDS             complement(21541..22479)
                     /locus_tag="ACGI3L_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFG9198257.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(22467..22865)
                     /locus_tag="ACGI3L_002559"
     CDS             complement(22467..22865)
                     /locus_tag="ACGI3L_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9198258.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT         9128 a         2624 c         4434 g         6770 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggctatatg atgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctacgcaggt
      181 gaggctggaa taagaactat aggatttggt ccttctaagg aaaatcttgc tcatacaata
      241 gatgagtata tagaattaga ccaattattc aaaggtgcag aaggatatta tggtatatta
      301 aaatcagttt ataaaaaata attaggagat ggttttgtga gaattttaat aaaacatggg
      361 cttatagtag atggaaataa aacaccagca tatgaaggag atattttaat agaaaacgag
      421 aaaatattaa aaatatcaca agatttaaac gaagaagctg acaaagttat agatgcaaaa
      481 ggtagagtta tatgtccagg tttcatagat actcatagcc attcagacct agttatttta
      541 gttaatccat ataatgaggt aaagattaga cagggaatta caacagaagt gttgggccaa
      601 gatggtatat ctatggcccc tctacctcaa gagcatatat cttcttggag aaaaaattta
      661 gcaggtctag atggtgaaag tgatgaaatt gattggaaat atgaaacaac agagaattat
      721 ttaaaaatga tggattacaa tggggtaggt ttaaatgaaa cttatttagt acctcatgga
      781 aacgttagaa tggaagctat gggacttgaa gatagacctg ctactaaaga agaaattcaa
      841 aaaatgtgtg aaatcacaga gagagaatta aaagcaggag ctataggatt gtctactgga
      901 cttatatata taccttgtgc atactcattg actgaagaaa ttatagagat gtgtaaggta
      961 gtagcaaaat atgatggagt atttgtagtt caccaaagaa gtgaagcaga tacaatttta
     1021 acttcaatgg aagaaatcat agaaattgga aaacaatcag gagtaaaagt tcatttttca
     1081 cattttaagg tttgtggtaa agcaaactgg aagtatatac cacaagttat agagctttta
     1141 gaaaaagcag aaaaggaagg aataagagta tcttttgacc aatatccata tgcagcagga
     1201 agtacaatgc ttggagtagt tttacctcct tgggcacatt ctggaggaac tgataagtta
     1261 atagaaagat taagtgatga aaacgaaaga gcaaaaatga aaaaagatat agcaaatgga
     1321 atagaaggct gggataattt tatagaattt gctggaatag accaaatatt tgtaacaagc
     1381 gtaaaaacag aaaagaataa agatacaatt ggtaagaact tattagaaat tggaaaaatg
     1441 agaggaaaag acccattaga tgcaacgttt gatttattaa aagaagaaga aaatgcagtt
     1501 gggatggtag atttctatgg attagaagaa catataatag gattcatgaa aagagacgag
     1561 caaaatgtgt gtacagatgg tcttttagca ggtaaaccac atccaagagc ttatggttct
     1621 ttccctaaaa tactaggaag atatgttaga gagttgaatg tgttaacaat cgaagaagct
     1681 gtttataaaa tgactaaaaa ggcagctaca agctttagta taaaagatag aggcgaatta
     1741 aaagaaggat attttgcaga tatagttata tttgacaagg atacagttag tggttgtgat
     1801 gattttatca actctatgca gtaccctaca ggtatagatt acgtaattat aaatggaaat
     1861 tgtgttgttg aagaaggaaa atacaataaa attaaagcag gaaaagtact taaaaattaa
     1921 atcttagctt taaggaggaa taaatttatg attttagtgg ggaatgggag gctaataagc
     1981 caagattctt taaatcccta tatggaagat ggatgtgtag taataaatga taatctaatt
     2041 gaagatatag gtactacaga agaaatgaaa gctaaatatc cagtacatga atttatagat
     2101 gcaggcaaga aaataatcat gccgggtcta ataaattcac atatgcatat atacagctca
     2161 tttgctagag gaatggcagt tccaggaaaa ccttctgaga actttttaga gatactaaac
     2221 aatttatggt ggagacttga caaacagctt acactggaag atacaaaata cagtgcatat
     2281 gcaacgtata tagaatgtat aaaaaatggt gtaacaacag tttatgacca tcatgcaagt
     2341 ccaaatgcaa ttgaaggcag tttgtttaca atatcagatg ttgcaaagga tttgggaatt
     2401 agaacgtgtc tttgttatga agtgtctgat agagatggtg gaaatacaat ccaacaaggt
     2461 atcaatgaaa acgtaaactt tataaaatac gctcaaaaag atgatacaga catgataaaa
     2521 ggaatgtttg ggcttcatgc tgcatttaca ctatctgatg atacattaaa taaatgtgct
     2581 tcagagatgg ctggtcttga tacaggttac catgtacatg ttgctgaagg actagcagac
     2641 ttacaatata atgtagataa atatggaaaa agggttttag aaagattcaa tgattttgga
     2701 gtactaaaag aaaaaacaat agcagttcat tgtatatata taagtgcaga agaaatcagt
     2761 cttttaaata aaacaaatac atttgtagtt cataatccag aatctaatat gggaaatgca
     2821 gttggatgtt ctcctgcaat agagttatta aaaaggggag ttacagtagg attaggaact
     2881 gatggatata ctagcgatat gtttgaatca ttaaaagttg ccaatataat tcacaaacat
     2941 cacttaaaag acccaagagt tggatttgaa gaatcacaaa caatgttatt tgataacaat
     3001 agaaaaatag ctaaagctta ttataaaaat gacctaggag tacttaaaaa aggtgcttat
     3061 gcagatgtta tagtagttga ttatatacca catactccat tgacagaaaa tacaataggg
     3121 ggacacacta tttttggaat gagtggaaga agcgtagata caactattat aaatggaaag
     3181 gtacttatga aagatagaaa gttaataaac atagatgaag aaagtattct agcaaaaagt
     3241 agagaattaa gtcaaaatct atggaataga atttaaataa ttgattatgc aaaattctat
     3301 gaagcaggaa ccctgtgact ttagtcatgg gaggttcaga ttaatataca agtaagaaac
     3361 aagaatttag atgttaaaaa cagagcttaa acaaaaatag gaatttaaat gaagtatata
     3421 aataaaaaat atacggaata gaatattaaa ttaaatatag aagggagacc caaaatgtct
     3481 cgagataaaa gccctaaaat agctccagta gatgaaaggt tacctgtatc caaatcttgg
     3541 gtattttcac tacagcacgt tttagcaatg tgtgcaggag cagtagcagt tcctatgatg
     3601 ataggaagtg ctgcacgact agatcatgct agtattgttt ttttaataaa tgcttgcttg
     3661 tttatggcag gtataggaac actcatacaa agtgttggta taggaaatat tgtaggtgct
     3721 aaaataccag taatagaagg aactagtttt gccgctgtgg caggtatgac agcaatagcc
     3781 tcatcatata gtgattcaca agttgcaata cagacagtat ttggctctgt aatagtagct
     3841 ggattgtttt gtatattact tgctccagta tttgaaaaat taataagatt tttccctagt
     3901 gtagttactg gaacagttgt tatggtaata ggtatttcac tatttccagt tgggataaaa
     3961 tggataactg acaacaaatt ggaagcggtt gaaccaaact cattagcatt agctttagca
     4021 gtattggcaa taactttact ttcatttaaa ttcttaaaag gaatttggaa tagcacagct
     4081 atattggtag gtatagtact tggtacacta ctttccatgg cagttggaat ggcagatttt
     4141 agtgcagtaa atggagttgg ttggcttaac ttaaatgtac ctttaaaatt tggaatgcct
     4201 agatttgaac catctgcaat actatcattg tgtttgatta tgttggtact tatgacggaa
     4261 tcagttggta atatgatagc tattcatgaa atggtagaca aagaagtaac aggtaaaaat
     4321 attaaaagag gtctatttgg agatggaata tctacagcat tatctggaat attcaattca
     4381 tttccaataa ctccatttgg tcaaaataca ggaatagtag gtcttacagg tataaaatca
     4441 agatttatag cagtttacgc aggggttata ttgctagtac ttggattctt accaaaattt
     4501 gcagcaataa taggagcaat acctaagcct gttcttggag gcgtaggatt tgcaatgttt
     4561 ggaatggtaa tggttggagg agtaaaaact ttaagcaaag tgaaatttga tggaactaaa
     4621 aatggggtta tagtagcagt tagtgttggt ttgtctatga taccactaac aaatcctgat
     4681 ttctatcata atttcccaac ttgggtacaa acaatattcc atagtggaat aacaacaggt
     4741 agtttatcag cagtgctttt aaacatattc ttcaatgaac taggttctaa aaaagaaaaa
     4801 aataataaag ttgaagaagc aaaataaaaa taaaacaagt aaaaatctat attgacttaa
     4861 agtcattaag tattaataaa aataattcag agatattaat aattcaacaa aactatctta
     4921 tattttaaat aatataaaaa agtaaataaa taacaaatac aaataaaaga atacaatcta
     4981 aatattaaaa atatttaatt taagggagag ataataatat ggctaattta aaagttaatt
     5041 tatatggaat ggaattttta aatccaatta tgacagcggc aggacctgga gcaaaagatg
     5101 gtgctctctg tcaagaggca gcaaaaggtg gagcaggagc tatatgtaca aaaactatat
     5161 ctgtattacc agctgatgta ccaagaccat gtatggcaaa aactaatagt ggttttttaa
     5221 acacagaatt atggtcagag cttccaaaag agcaatggat agaggaagaa tacaaaaagg
     5281 taaaagaaac agggcttcca gtaatagtaa gtatgggata ttcagcagag caaatagctg
     5341 aggttgctcc tttagtaaag ccttatgcag atgcagttga attatctact cattatgtag
     5401 gtacagacgt tgcaccaata gtaaatgctt taaaagctgc aaaagctgtt ttagatgtac
     5461 cagtatttat gaaaatgagt cctcatactg acattcaaac tattgcaaaa gctgttgaag
     5521 aagcaggtgc agatggactt gtaatgataa actcatttgg accatgtatg gcaatagatg
     5581 taaatacagg ataccctata atgggaagta aagctggata cggatggtta tcaggtgcac
     5641 caataagacc tctagcaata agatgtatat atgaagcttc tcaagttgta aatataccaa
     5701 taatcggtgt tggtggaatc acttgtggaa aagacgtggc tgaaatgatg atggctggag
     5761 caagtgctgt tcaagtatgt acagaagcaa tccttaaagg gccttctatc tatggaaaaa
     5821 ttgctaaaga attaaatgaa tttttagatg agaatggata tgctgatgtt aatgaaataa
     5881 aaggactaac tcataagaaa atggcagcta gagggtttag aactcattca gtagctccag
     5941 tagtggatga taacaagtgt atcaaatgta agcaatgtgt aacaagctgt gtatacgaag
     6001 ctttagaagt tacagataag ttgaacatag atgcagacaa gtgttttgga tgtggattat
     6061 gtgtaactag atgtccaaaa ggagctttaa gcatctgcta caatcaagta gaagctatga
     6121 atgagtaata attatataga attttggtaa ttaacttaga gtaataggta ttaggataat
     6181 aaaatatatc agataaacaa acacacatta tgcattaata atacagtcta aagttaataa
     6241 ttttattata ttgatttaac taaatattag tttagctgaa tattaattta attaggtatt
     6301 ggtttaatct taatatagat ttactgcgta taagtgaact aactagatta ctttaagtta
     6361 attttttcat ataaaataaa ttgatacatt acaagtaagg tggagtctat atgggaattg
     6421 ttttaaaagg tgggaaagta gtaacaagtg aaaaaactta ctgtgcagat gtaagaatag
     6481 aagatgaaaa aatagtcgat ataggtcttg atatatcaaa agaaaatgat gaaatagttg
     6541 atgttagtga ttcttatgtt ataccaggag gtatagatac acacacacac tttgacttag
     6601 atacaggcgt tactaagaca gcagataact ttgagacagg aacaaaagct gctatagtag
     6661 gaggaactac tactatattg gattttgcta cacaagctaa aggatgttct ttgaaagacg
     6721 gattagaaga atggcatgaa aaagctaagg ataaatccta ttcagattat ggctttcata
     6781 tggctataac agattggaat gactcggttt gtaatgaaat ggaggatatg gtgaaagagg
     6841 gagtatcttc atttaaactg tatatggcgt ataaaggaag ccttcaagtt gatgatggtg
     6901 taatctttga agcattgaga aaagcagaag agataggagg gattattggt ttccattgtg
     6961 aaaatgggga cataatatgt gaacttgtgg ataaagcaaa gtcagaaaat aatttatctc
     7021 caaaatatca tcaattaact agaccagcta taatggaggc agaagctaca tcaagactta
     7081 tgaagatagc tgaagttgca aactctaaag tatatgtagt tcacttaagc tgtaaagaat
     7141 ccttagagga ggttttaaaa gctaagcaaa gaggtgtgga tgtaatagtt gaaacttgtc
     7201 ctcaatacct tctattaaat gatgaattat atgatttaga tggatttgaa agtgctaagt
     7261 atgtaatgtc accaccttta agaaataaag aaaataatga aatattatgg aatgctattt
     7321 tagataatca aatagacact ataggaacag accattgttc ttttaattat aagggacaga
     7381 aggaacttgg gataaacgat ttcagtaaga taccaaatgg ttctccaggt gtagaacata
     7441 ggatgagtct tttatacaca tatggagtct gtaaaaataa aatatctatc aacaagatgg
     7501 tagaagtaac atcaactaat gcagcaaagt tgtttggaat gtatcctaat aaaggaacta
     7561 tagaaatagg cagtgatgca gatatattag tcttaaatcc aaacaaaaaa tccaaaatag
     7621 aagcaaaaaa acaattacaa aatgtagatt atacacctta tgaagggtat gaagtggatt
     7681 gtcaaataga acatgtttat ttaagaggaa aagaagtagt tagagatgga gaattaattt
     7741 gtaatactcc aagtgggaga tatataaata ggcgtctaac aaagggggct agagaatggt
     7801 agaatttata ttaaatggag agaaagttgt tgcaaaagaa ggcaaaaaac ttttagactt
     7861 ccttagagaa gatatgaata taacttcagt taaaaatgga tgttcagaag gtgcttgtgg
     7921 aacatgtatg gttataatag atggtaaagc tactaaagca tgtgtattta aaactgataa
     7981 attagctggg aaaaacataa caactataga gggattatca gagagagaaa gagatgtttt
     8041 tgcatattct tttgctagtc aaggagctgt acaatgtgga ttttgtattc caggtatggt
     8101 aattagttca aaagcactta tagacgttaa taataatcct actgaagatg atataaagaa
     8161 agctttaaaa ggtaatatat gtagatgtac agggtatgta aaaataatta aagctgtcga
     8221 tttagcggca aagattttta gagaaaatat agatgtgcca aaagtaaact gtaagggtct
     8281 agtaggtgaa aatcttccta gagttgatgc agttggcaaa gcacttggat attctgaata
     8341 tgtagatgat atgagaattg agggtatgat ttatggttca gcagttagag ctaagtatcc
     8401 tagagcttta gttaaaaaaa tagatataga agaagcaaaa gcttatccag gagttgttgc
     8461 agttctaaca gctaaagata ttccaggaac tataaaggta gggcacttaa agaaggattg
     8521 ggatacttta ataccagaag gtgaaataac tagatactta ggagatggaa tagttttagt
     8581 agcagcagaa actagagaag cgttagaaga ggccaaaaag ctagttaaga tagattatga
     8641 ggaattaaca ccattaagta ctacagcaga tgcacttaga gaagatgctc caaagataca
     8701 tgagacaggg aatatacttg ttaaggaaca tttagtaaga ggaaacgcta aagaaaagat
     8761 agaaaattca aaatatgttg taactaaaag atatactaca cctgctacag aacacgcatt
     8821 tttagagcct gaatgtgcag tagctggtcc ttatgaagat gatggagtaa taatctattc
     8881 gacagaccaa ggggtgtttg ccactcaaca tgaatgtgca gatatgttag ggttaccata
     8941 tgagaaggta agagttataa acaaaatggt aggaggaggg tttggtggaa aagaagacat
     9001 gagtgttcaa caccatgcag ccttacttgc ataccataca aagagatttg taaaagtaca
     9061 gttaacaaga aaagaaagta ttattgttca tccaaaacga catgccacag aaatggaatt
     9121 tacgacagca tgtgatgaaa atggatactt aacgggtatg aaggcaacga taatatctga
     9181 cacaggtgca tatgcctctc ttggaggacc agtgctacaa agactgtgta ctcatgcagc
     9241 aggaccatac aattatcaag atattgatat aacaggaaca gcagtatata ctaataaccc
     9301 tcctggagga gcatttagag gatttggagt tacacagagt tgttttgcaa ctgaatgtaa
     9361 tctaaattta cttgctgaaa tggttggaat atctccttgg gagataagat ataaaaatgc
     9421 aataagacct gggcaagttt taccaaatgg tcaatttgca gatgaaggaa cagcaatggc
     9481 agagacacta gaagctgtaa aagaagagta tgaaaagcat ccacgtgcag gtatagcttg
     9541 tgctatgaaa aatagtgggg ttggagttgg tatacctgat gttggaagat gtagattggt
     9601 gataaaagat ggcaaagttc acataagaac aagtgcttct tgtataggtc aagggcttgg
     9661 tactgttatg actcaagtag tttgtgaaac tgctaaccta cttcctgaaa atatagttca
     9721 tgaagttcca gatactcatt taacaccaga ctctggtaat actacggctt caagacagac
     9781 agtatttacg ggagaagcta ctaaggttgc atcaaataag ttaaaagaag ctttagactc
     9841 tggcaaaact ttacttgatt tagagggaga agagttttat ggagaatatg aaagtattac
     9901 agataaaatg ggttgtgaca aagaaaatcc agtaagtcat gttgcttatg gatatgcaac
     9961 acaagttgta attctggatg aaaatggaaa actagaaaaa gtagtagcag cacatgatgt
    10021 tggaagagct ataaatccaa tcagtttaga aggtcaaata gaaggtggag tagttatggg
    10081 tcttggatat gctctaaccg aagattaccc agtagttaac tctattccta cagctaagtt
    10141 tggtacatta ggtttattta aatctacaga tataccagaa atacaagctt taatagttga
    10201 aaagaacaaa gatttattgg cttatggggc aaaaggtgta ggagaaattt gtacagttcc
    10261 tactgcacca gcagtacaaa atgcctatta tgtatttgat aaagaattta gaactgagtt
    10321 accactacaa aatactccat atagtaaaaa aaagtaacaa aaaaaagaaa tattaaataa
    10381 aaaaatagat gaaattgtaa ataaaaaaaa cccttttgca taaggtatat tttaaatgat
    10441 agaatataca tatacaggag ggtttttctt ttataaaata agtttaataa aattgagagg
    10501 tgagcagaat gaattttaat aatagtctag aattaactca gtctcagaag ctaataatga
    10561 ctacacaact taagcaatca ttatcaatat taaatatgag taagttagag ttagaagaag
    10621 agataaaaag agaagcagag aataacccat tagttgaagt cgagaaaagt ggggagataa
    10681 attgggaaga gtatataaaa gacatggata ggtcaagacg tttagataga acagagataa
    10741 gctataatcc tgataatgaa gttaatctag aaaatttagt taaatattcg tcaaatttat
    10801 atgaagattt aaaatttcag ataagcctgt ataaacttac agacaaagaa ttggaagtct
    10861 gtgagtatat aattgatagt ttagatgagg atggatattt aagaactgag gaaaaagtaa
    10921 ttgttgatac cttaaagata gatgaagaac tttttgaaaa atgtttaatt agtgttcagc
    10981 agttggaacc tagtggagta ggggcaagaa gtctttcaga atgtctgatg atacaaatgg
    11041 ctagtttagg aatatataat gaaattttag aggaaatcgt tacaaaagac ttaaatttaa
    11101 ttgcaaataa taaatacaaa gagataagta aaaagtacaa tatgtcatta caaaaatgtg
    11161 ttgaactaat aaatataatt aagacattag accccaaacc aggaagaact tgttcagtag
    11221 agaaaagtgt atacattcaa cctgatgtaa cagtagaaaa aattgatgat gaatttattg
    11281 tatatttaaa tgagaaagat tcttatcaaa taagaatcaa tagttattat aaagacatat
    11341 taaaaaattc acagtctgat gaaagtgcaa aagaatttat aaaagaaaga ctaaattcag
    11401 caacaggact tatgaaaaat atagagagta ggaaaactac agtacttaag attgcagaag
    11461 agatagtaaa agctcaagat gaatttttga gaaaagggac aaaatatata aaacctttga
    11521 aaatgaaaga catagcagaa aaattagaat ttcatgaatc tactataagt agaggtgtaa
    11581 atggtaaata tatgctaaca ccttttggcg tatatgaatt taggtacttt ttcagtagcg
    11641 ccattgagac tgagaataat gaaatggcat ctagtacaag cataaaaaaa attataaagg
    11701 aaacaataaa agacgaaaat aaaaagaaac ctttaagtga tgaccatata tctaagttat
    11761 taaaagaaaa aggaatcaat gttgcaagaa ggacagttgc caaatatcgt gaagaattag
    11821 gaatcccatc ttcaagtaag agaaaagaat actaataagt aaaagacaaa tatcagtatg
    11881 gtaaggggaa aaggctaatt aagagatgaa tgtagattgg gctaaaaatt ttataaagta
    11941 aaataatata atatgaaaaa gtattaaaat gctataaggt attaaaaaac tggggaacat
    12001 taaaacatta agatagcaaa gagcataaaa aactaaagaa gattaaaaca ttaaagaaca
    12061 ttagagcttt gaggaatatt agaactttaa agaatattaa aatttataaa atataaaaat
    12121 actaaaaaga attgaaaaac tggggaacat taaaatattg taaaatgcta aaaaactaga
    12181 aaacataatt aaataagtgc ttataaagaa tgattaaatt aaataagtgt ttgtaaagaa
    12241 taattagata ttagaaaaag aagaatacct agataaataa actattatta aatttaataa
    12301 tcacaaaagg aaaacacgta gggtataaat aaaaatctta actagataaa agtaaactta
    12361 gttgtagata aaaataacta gaaataaaat tatttatagt aataaatatt agaatgaaaa
    12421 tataaaaaaa tatatataaa aagccttata taaaaagaaa aaatactgtg atttgaaaat
    12481 ggtggagaaa tattttataa aataaaaaaa taaaaaagtt tttgaaaaac tattgaaatc
    12541 tatacgcaaa tcctataaaa taaaaatatc ttgtgggact taaataaaca ctagggacaa
    12601 aaaaagtccc gaaaggaaag caataaggag tatgttatga agaacttatt agaaattcaa
    12661 aagaaattga ttccacaggc aattgaactt atggaaagaa gatactctat tttaagacaa
    12721 atatctttaa gtgaaccaat aggtaggaga acattatcaa atgtattaga gattagtgaa
    12781 agaataatca ggtcagaaac tgagttttta aaagaacaag gacttataga cgtagctgta
    12841 tctgggatga ctatcactaa agaaggttct gatttgttag ataaacttaa ggacatcatg
    12901 agtgacatca tgggattgtc taagttacaa gatagagtca gagaaaagct tggaataaaa
    12961 agggtaatat tagttcctgg aagctgtgat gaaaatggaa gtttactaaa agatgtaact
    13021 agatatggat gcgaatattt cttaggcatt ttaaaagatg gagatatcgt ttcaataaca
    13081 ggaggaagca ctatgttgga gttttcaaac gttattaaaa ctgataagag atatccaaac
    13141 tctacaatag ttccagctag aggaagtatg ggaactgatg tagagatgca atctaacaat
    13201 atagttgctt caataagtaa gaaattacat tctaattgca aacttttaca tataccagat
    13261 gagttggatg aaagtgcaat gaaaactctt agccaagtgc cagagattaa gacaactttg
    13321 gagtatatta aaagaacaga cattttagtt tttagtatag gtagagcaga tgtcatggca
    13381 aagagaagaa aacttccaga agacaaggtt gatgagatat tatctaaaaa tgcagttgga
    13441 gaagcatttg gatattattt caacaaagat ggagaaatag tttacaaact gaacactgtt
    13501 ggaattgatt tagaaacagt taaacaagta aaagaaacta ttgcaatctt tgcagggact
    13561 gaaaaagtag aagccttatt agctatatca aatatgcata aaaacatggt tcttgtaaca
    13621 gatgaagaaa gtgcttataa gatattgtca ttattataaa agtcaagacc tagcacagag
    13681 ctagaaaaca tacatttact ttataggagg tagcgaaaat ggttaaagta gctataaatg
    13741 gatttggaag aataggaaga ttagcattaa gaaaaatgat ggagcaacaa gataagttcg
    13801 aagttgttgc aataaacgac ttaacagacg ctaaaatgtt agctcattta tttaaatatg
    13861 atacagctca aggaagattt aacggagaaa tagaagttaa agaaggtgct tttgtagtaa
    13921 acggaaaaga aataaaagta acagcagaaa gaaatcctgc tgacctacca tgggctgaat
    13981 taggagtaga tatagtatta gaatgtacag gattctttac atctaaagat aaagctgaag
    14041 ctcatataca agcaggggct aagaaagttg ttatatctgc accagctact ggagatttaa
    14101 aaacaatagt attcaacaca aacagtgaca tattagatgg ttctgaaaca gttatatcag
    14161 gagcttcttg tactactaac tgtttagctc caatggctaa agtattaaat gataaatacg
    14221 gtatagaaaa aggcttaatg actactatac atgcatacac taatgaccaa aatactttag
    14281 atggtcctca tccaaaaggt gatttaagaa gagctagagc tgctgctgga aacatagttc
    14341 caaacactac aggagctgca aaagcaatag gcttagtaat accttcatta aaaggaaaat
    14401 tagatggggc agcacaaaga gtaccagttg taactggttc aataactgaa ttagtttgta
    14461 cattaggaaa aaatgttaca gttgaagaaa taaatgcagc tatgaaagaa gcttcaaacg
    14521 aatctttcgg atatactgaa gaaatgttag tatcttctga cataatcgga ataagctacg
    14581 gttcattatt tgacgctact caaacaaaag ttatggaagt agatggaaaa caattagtta
    14641 aagttgtttc ttggtatgat aatgaaatgt cttatacttc tcaattaata agaactttag
    14701 gatactttgc acaattagca aaatagtcag ttttgagaaa atagaaaagt agattgacaa
    14761 agtccgagtt tgtagtttaa tactacggac tcaggacttt ttttaagaaa aaatatataa
    14821 aatacaccta aataatgtta catactatat ataaaaatat gataatatga tatatttaat
    14881 agggtaaaag tatgtactat attatacttg gcaataaaaa attactttat taaaaggaga
    14941 gatatttatg tcaatgctta acaaaaaaac tatagaagat attgatgtgt gcggaaaaaa
    15001 agtattagta agatgtgact ttaatgtgcc attacaagat ggtgtaatta ctgatgaaaa
    15061 tagattgaac ggagctttac caactattca atatttaatt tctaaagggg caaaagttat
    15121 attatgctct cacttaggaa agccaaaagg agaagctaaa ccagaattat ctttagcacc
    15181 agtagcaaag agattatctg agatgttagg aaaagaagtt gtatttgcag cagacgataa
    15241 tgttgtagga gaaaatgcaa agaaagcaac tgaaaaaatg gaaaacggag atgtagtatt
    15301 attagaaaat actagatata gaaaagaaga aactaaaaac gaagagaatt tctctaaaga
    15361 actagcatca cttgctgaaa tatttgtaaa tgatgcattt ggaactgctc atagagcaca
    15421 ttgctcaaca gttggtgcag gcgagttttt acaagagaga gtttgtggat acttaattca
    15481 aaaagaatta aaattcttag gagaagctgt tgcaaaccct gtaagaccat ttacagctat
    15541 acttggagga gctaaagttt ctgataaatt agctgttata aacgaattat tagaaaaagt
    15601 tgataatcta ataataggtg gaggaatggc ttatacattc ttaaaagctc agggttatga
    15661 agtaggaact tctttacttg aaatagataa agttgaatat gctaaagaaa tgatggaaaa
    15721 agctaagaat aagggtgtta acttattatt accagtagac gttgttatgg cagaccactt
    15781 tgcaccagat gctactccaa tagtaacaga agatgctaat gtaaaagaag attacatggg
    15841 actagatatg ggacctaaga ctatagcaaa ctttgtaaaa actataaaag aatcaaaaac
    15901 tgtagtatgg aatgggccaa tgggagtatt tgaatttgaa aactttgcaa atggtacatt
    15961 atcagtagct agagctatgg cagagttgac tgatgcaact actgtaattg gcggtggaga
    16021 tagtgcagca gcagttaatc aattaggatt tggtgacaag atgactcacg tatcaacagg
    16081 tggaggagca tcactagaat ttttagaagg taaagaatta ccaggtattg cagcattaga
    16141 taataaataa actaatatat agaggagatt gtaaaatgag aaaacctata attgcaggaa
    16201 actggaaaat gcataaaaca ataaaagaag ctttagaatt tgtaaatgaa gttaaagata
    16261 aagtaaattc tgataaagta gaagctgtta tatgtgcacc atttacttta ttaaaggatt
    16321 taaaagaagc tactaagggt acaaatataa agataggtgc tcaaaatatg cactttgaag
    16381 aaaaaggagc atttacagga gaagtttcac ctcttatgtt aaaagaaata gatatggact
    16441 atgttgtaat aggacattca gaaagaagac aatacttcaa tgaaactgat gaaactgtaa
    16501 acaagaaagt tttaaaagca ttagaagtag gaatagaccc aatattatgt gttggagaaa
    16561 ctttagaaca aagagaagct ggaaaaacta aagatgtttg taaagttcaa gttgaaaaag
    16621 ctttagaaaa tgttcttaaa gatgatttag caaaagtagt tgttgcatat gagccaatct
    16681 gggctattgg aactggtaaa actgcaactg ctgaagatgc taatgacgtt atatcttata
    16741 taagagaagt tataaaagga ttatatggag aattagctaa tgaagttaga atacaatacg
    16801 gtggaagtgt taaaccttca aatgtagccg aaataatggg tcaaagtgat atagatggag
    16861 ctttagtagg tggagctagt ttagctagta atgattacct agaccttgtt aatttctaag
    16921 gagtgaaatg atgaaaaaac cagttgcttt aattattatg gacgggtttg gatacaataa
    16981 ggatgttaag ggaaatgcaa ttgctgagtc caaaactcct aatttagata gaataaaaaa
    17041 agagtatcca aacacattga taaatgctag tggtcttgat gttggtctac ctgatggtca
    17101 aatgggaaat tcagaagttg gacacactaa cataggtgca ggtagaatag tatatcaaga
    17161 tttaactaga ataacaaaat ctataaaaga tggtgacttt tttactaata aagttttatg
    17221 tgaagcaatg gataatgcaa aagaaaactc tcttcatgta atgggacttt tgtctgatgg
    17281 aggagtacat tcacatatag accatcttaa ggctataatc aaaatggcaa aagataaagg
    17341 cgtacaaaag gtgtatgttc acgcatttac tgatggtaga gatactgacc ctcaaagtgc
    17401 attagaatat gccaaagaag tacaagctag tatggatgaa attggagtag gtgaatttgc
    17461 tacagtttct ggtagatact acgctatgga tagagataag agatgggaaa gagtagaact
    17521 tgcatacaat gccatggtta gaggtattgg tgaaaaagca aattctattg aggaagctat
    17581 tcaaaactct tatgatgatg gaaaaaatga tgagtttata atgccaacag ttattatgaa
    17641 agatgataaa ccagttggaa gtataaagga aaatgattca attatattct tcaactttag
    17701 accagataga gctagacaaa taactagagc tttagtttgt gaagagtttg atggatttaa
    17761 aagagaagat attaaaaact tctttgtatg cttaacagag tacgatataa ctatagagaa
    17821 tgtgcatata gcatttggac ctcaatcttt agccaacact ctaggtgagt atctagctaa
    17881 aaatggaaaa actcaactta gagctgctga aactgaaaag tatgcacatg taactttctt
    17941 cttcaatggt ggagtagaag agccaaataa aggtgaagaa agactattga taccttctcc
    18001 aaaggttgca acttatgatt taaaaccaga aatgtcagca tatgaattga cagataaagc
    18061 tttagataaa ttaggagaag ataagtttga ctttatagta ttaaactttg caaatcctga
    18121 tatggtaggt cacacaggaa gtatagaagc ggctataaag gctgttgaaa ctgtagatac
    18181 ttgtgtagga agattgatag ataaaatagt agagttaggt ggaagtgcaa taataactgc
    18241 tgaccacgga aatgctgaat atatgttaga cccagaaaca ggaaaaactg taacggctca
    18301 ctctattaat ccagtaccat ttattgtagt tggtcaagaa tatgaaagtg caaaattatt
    18361 ggatggagga agattatctg atatagcacc tactatttta gatatgatga agttagaaaa
    18421 gccagaagaa atgactggtc attcacttat ttcaaaatag tcgattctga taagtagata
    18481 ataatatata aactacaata taaatttaaa aataatgcag tttaggttta ttttgtaaag
    18541 tttagacttt atgacataag gtttaaattt tgtaagttct ggatattgta aggtgtagat
    18601 gaagatatat tttataaaat ttacaagata gacaatttat aaaataaaaa attacaatat
    18661 agataataat gtaaataatg atataaataa taacaagata gacaataaca atataaataa
    18721 taataattaa tatatattat ataagcaaaa attttagaat cattagttgt acattttatg
    18781 tttaatgttt taaatctagt tataatattt gtgtatttaa gattggtttt ggattttaga
    18841 caagtttttt tatattatat aaattaaaat attataaaaa ataaaataaa aataggaact
    18901 tttacaaatt tacccatcaa ataaatttgt acctaatttt caaaagcaac tttatgtact
    18961 ataatataga aagtagatta aaatagtaga cggatgttta cagtaaatga aaatttaact
    19021 aatagaaaat cgaagggaga tatacaaatg tcagttattg aattagtata tgctagagaa
    19081 gtattagact caagaggaaa tccaactgta gaagttgaag tagtattaga agatggagca
    19141 atgggaagag caatagttcc atcaggagca tctacaggag cttttgaagc tgttgaatta
    19201 agagatggag ataagggaag atacttagga aaaggtgtag aaacagctgt tgctaacgta
    19261 aatgaaataa tagcacctga aatagaagga atggatgcat ttgaccaacc agctatagat
    19321 gcaatcatga tagaattaga tggaactcca aacaaaggta aattaggagc taatgctata
    19381 ttaggtgttt caatggcagt agctagagca gctgctgatg aaataggttt accattattc
    19441 caatacctag gtggagtaaa tgctaaacaa ttacctgttc caatgatgaa catattaaac
    19501 ggtggagagc atgctgataa caacgttgat gttcaagaat ttatgatatt accagtagga
    19561 gcttgttgtt tcaaagaagg tttaagaatg ggagcagaag tattccattc gttaaagaaa
    19621 gttttaggag aaaaaggatt agcttgtggt gtaggtgacg aaggtggatt tgctccaaac
    19681 ttaggttcaa acagagaagc tttagaatta atagttgaag ctataacaaa agctggatat
    19741 aagccaggtg aagacgttat gttaggtctt gacgttgctg ctacagaaat gtacaacaaa
    19801 gaaactaaaa aatacgtttt agcaggagaa ggaaaagagt taactgctgc tgaaatggtt
    19861 gctttatatg aagattggtc aaacaacttc ccaataataa ctatagaaga tggtttagac
    19921 gaagaagatt gggatggatg gaaattatta actgaaaaat taggaaataa attacaatta
    19981 gttggtgacg acttatttgt tactaacaca gagagattag aaaaaggaat tgaaaatgga
    20041 gtagctaact ctatattagt taaagttaat caaataggta caataactga aactttagat
    20101 gctatagaaa tggctaagag agcaggatat actgctgtta tatctcacag atcaggagaa
    20161 actgaagatt ctactatagc agatttagct gttgcagtaa atgctggtca aataaaaact
    20221 ggtgctccat caagaactga tagagttgct aagtacaacc aattattaag aatagaagaa
    20281 atggttggag agcaagctag atattgtgga ttaaaatctt tctataactt aaaaaaatag
    20341 ttattaaaat ggttactaaa aaagattaat gaagagagaa tataagatat ttaagctcat
    20401 cttataagat ataaaagaga taagtgttaa ttgatttttc aattcactta tcctttttta
    20461 tattttatta cttaatttta ttcatagatt cagaaaaaat atgaataaat gtttctatct
    20521 catttttatc taattgcata ggaggttttt attaaaaaat aaaagtgaag acatattttg
    20581 atttaatcat aattgtcatt gaagtattat tgctaaatgt ggattattta ttttaaatta
    20641 tgttgaaatt aaaagttata tcaatatttt aaaatgattg ttttattttg gtggctattt
    20701 ataatatata caatgagagt agattatttt aagtgttaat ttatgtatta atttaaatag
    20761 ttttctcttc taagttttat tcatttttat attgagaata tagtaatata ttatagtaac
    20821 aatatatttt tttgtatgtt atttatagca taatagtctt gaaatggcta tattattgtg
    20881 atacactaaa gagtaatgaa atttaagtaa taaacagata ggaggggcaa gaatgagcaa
    20941 cattttaatg ggtgtgcaag tagtactagg gattttacta gtaattagca taatgcctca
    21001 agattctaag aatgctttac cttcagaatt tggtggagaa ggaagtcaag cttactttaa
    21061 accaaaagga aaacaagcat ttcttgctag agttacaaag ataacagcag tattattttt
    21121 tataaatgca ttggcattac ttatagttaa gaagtagtga tattgttgaa taactggcca
    21181 ttatttaatt agtgcatttg ctagacattt aaaaattaaa tttagttttt aataaaagta
    21241 catcaacata aaaagtacgt aaaataaaag ctggactaat gattttatat gattagtcca
    21301 gtttttattt tatagattga ctatttggtg gcgtttatta tttgtattta tatattgttt
    21361 gtatttatat attttcttca aactaaaaaa tatatagcaa cactactttc accatgttta
    21421 atgagataat atacacaaag ttatattata tagtaaaaat agtataataa tatgttttta
    21481 cgcgattaaa tcagttttat atatgtttct tataatacca atttgtgtta tcaaatatca
    21541 ttaaataaga ttattctgct ttaaaataaa tattattaaa aatactgtaa ttatagaaaa
    21601 tccagaagta aatactacaa tttgtccagc taattcactg tcagaatcca tctgttgtgc
    21661 cattgtaaat gaagaaactg cagttggagc agataacatt atcataagtg aagctaattc
    21721 tacatttcta aatccaagaa aaatgctaat tggtaaaaat atagcaggta caagtataag
    21781 ttttccacat acgcccaata taatgggttt tatatgcccc tttatagcag aaaaactaaa
    21841 agagccgcct agaattataa gtgataaagg agtagctatt ttagaaatat caccaatagt
    21901 tttgtgtaaa aatgtaggta tattaatatt taaaattagc attgtcaatc ctataaaaga
    21961 ggcgattatg agtggatttg ttaagacgct tttaatcata tgttttatat ttactttgcc
    22021 acctctaaaa atttcaagaa ttacaacaga taatacatta aacataggta caataactgc
    22081 aattaataaa gatgtgactc caatactctt atcgccaaat agtgaaattg tcacaggaat
    22141 accaaatata acgaaattgc tacgaaatac accttgtatt aatgcacccc ttgtcttatt
    22201 atctttttca attttaggaa taataaagac taagattaag aagattgaaa aaataattat
    22261 aacagctaca gccataagct taaaattaag agaaccatct aaatctgtat tgtatatatt
    22321 aaaaaataat aataatggca agaaagactt gaagcaaaca ttattcattt tatttaaagt
    22381 atgagtatca aatagaccta atttttttag aacatatcca agtgacattg tgagaaacaa
    22441 aggaagaaca acatttattg ataggattaa attttccaag gtttactctc cgtgattcta
    22501 tgatttgata attcaattaa atttccatta gtttttttca aataaataga tttcatatta
    22561 ccaaagacac ctgtacattc tacaattcct ctcttaattt gaatctcatt ttgttctaag
    22621 tatttttttg gctcatcaat atttgtgttt attttaaaac ataagttatc tctacttgct
    22681 tttgaatttt taacataagg taaaaattta taacctttta tgttaagatt tatcttaaca
    22741 tttctagcat taagtttata atttttgctc atttctttag atgaaaaacc aaatttttta
    22801 taaaaattga tataattttc tatattatta ttagtaatga ccacatgttc tatttttttt
    22861 atcatggcaa ctccttaaga ttttatataa attagttaaa tttatataag ttattaaatt
    22921 ttatatagat tgatgatatt tatataaatt attaaa
//
LOCUS       DAYAKB010000054        22876 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.054, whole genome shotgun sequence.
ACCESSION   DAYAKB010000054 DAYAKB010000000
VERSION     DAYAKB010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.054"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..163
                     /locus_tag="ACGI3L_002560"
     CDS             <1..163
                     /locus_tag="ACGI3L_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9198259.1"
                     /translation="GFGFISMEGRDDVFAHFSAIQTSGFKSLEEGQQVSFDIVKGARG
                     PQAENITIL"
     gene            1168..2013
                     /locus_tag="ACGI3L_002561"
     CDS             1168..2013
                     /locus_tag="ACGI3L_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9198260.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(2237..2401)
                     /locus_tag="ACGI3L_002562"
     CDS             complement(2237..2401)
                     /locus_tag="ACGI3L_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198261.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(2943..3275)
                     /locus_tag="ACGI3L_002563"
     CDS             complement(2943..3275)
                     /locus_tag="ACGI3L_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFG9198262.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(3519..4160)
                     /locus_tag="ACGI3L_002564"
     CDS             complement(3519..4160)
                     /locus_tag="ACGI3L_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFG9198263.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(4141..4434)
                     /locus_tag="ACGI3L_002565"
     CDS             complement(4141..4434)
                     /locus_tag="ACGI3L_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autorepressor SdpR family transcription factor"
                     /protein_id="HFG9198264.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            4815..4886
                     /locus_tag="ACGI3L_002566"
                     /pseudo
     CDS             4815..4886
                     /locus_tag="ACGI3L_002566"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(5057..5191)
                     /locus_tag="ACGI3L_002567"
     CDS             complement(5057..5191)
                     /locus_tag="ACGI3L_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198265.1"
                     /translation="MNISRRAMKIIELAQKIANKRGVTVQDAWNDAMKEYKEKYEYVA
                     "
     gene            complement(5402..6154)
                     /locus_tag="ACGI3L_002568"
     CDS             complement(5402..6154)
                     /locus_tag="ACGI3L_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFG9198266.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(6213..7868)
                     /locus_tag="ACGI3L_002569"
     CDS             complement(6213..7868)
                     /locus_tag="ACGI3L_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9198267.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(9141..10220)
                     /locus_tag="ACGI3L_002570"
     CDS             complement(9141..10220)
                     /locus_tag="ACGI3L_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9198268.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIFNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(10304..10960)
                     /locus_tag="ACGI3L_002571"
     CDS             complement(10304..10960)
                     /locus_tag="ACGI3L_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9198269.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            11282..11488
                     /locus_tag="ACGI3L_002572"
     CDS             11282..11488
                     /locus_tag="ACGI3L_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198270.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(11641..12069)
                     /locus_tag="ACGI3L_002573"
     CDS             complement(11641..12069)
                     /locus_tag="ACGI3L_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFG9198271.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(12545..13483)
                     /locus_tag="ACGI3L_002574"
     CDS             complement(12545..13483)
                     /locus_tag="ACGI3L_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HFG9198272.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            complement(13997..14809)
                     /locus_tag="ACGI3L_002575"
     CDS             complement(13997..14809)
                     /locus_tag="ACGI3L_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9198273.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLVEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(14835..15464)
                     /locus_tag="ACGI3L_002576"
     CDS             complement(14835..15464)
                     /locus_tag="ACGI3L_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9198274.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            complement(15808..17463)
                     /gene="ilvD"
                     /locus_tag="ACGI3L_002577"
     CDS             complement(15808..17463)
                     /gene="ilvD"
                     /locus_tag="ACGI3L_002577"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HFG9198275.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(17787..18086)
                     /locus_tag="ACGI3L_002578"
     CDS             complement(17787..18086)
                     /locus_tag="ACGI3L_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198276.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            18346..19026
                     /locus_tag="ACGI3L_002579"
     CDS             18346..19026
                     /locus_tag="ACGI3L_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFG9198277.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            complement(19136..19393)
                     /locus_tag="ACGI3L_002580"
     CDS             complement(19136..19393)
                     /locus_tag="ACGI3L_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198278.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            19942..20313
                     /locus_tag="ACGI3L_002581"
     CDS             19942..20313
                     /locus_tag="ACGI3L_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9198279.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            complement(20310..20450)
                     /locus_tag="ACGI3L_002582"
     CDS             complement(20310..20450)
                     /locus_tag="ACGI3L_002582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198280.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(21115..22011)
                     /locus_tag="ACGI3L_002583"
     CDS             complement(21115..22011)
                     /locus_tag="ACGI3L_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9198281.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            22152..>22876
                     /locus_tag="ACGI3L_002584"
     CDS             22152..>22876
                     /locus_tag="ACGI3L_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9198282.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSII"
BASE COUNT         7891 a         3660 c         2454 g         8871 t
ORIGIN      
        1 aggattcggt tttatatcaa tggaaggtag agatgatgtg tttgctcatt tctcagctat
       61 acaaacttca ggatttaaat cattagaaga aggtcaacaa gtaagctttg atatagttaa
      121 aggtgctaga ggtcctcaag cagaaaatat aactatatta taatatatag atttttcggg
      181 aaagactctt tttagagtct ttttttattg ttaatatatg taagataatc attggtgaag
      241 taaataaggt atattgagta atgttcttga tagtttatat gctaatgaat ttcaaaaaaa
      301 taagcactcc tataaaaaga gtgctcttaa tgtaaatata aaccttcatt ggtccagcct
      361 aataccccgt attctccaag ttctaactat tttttatata cattatcact ttcatccata
      421 tctaacacaa ttatttcttc tttagaatca atttgtaaaa tatgaggact gtgtgttgtg
      481 acaattattt gtgtttttag gagaattgct tttaatgtaa taaaaatttt acataccaca
      541 tagttgatat aaaactataa taattacata agattgtaat aataagactt atctttacat
      601 accacatagt tgatataaaa caatgaaatt aacatacaag agactaagac aattaaaatc
      661 tttacatacc acatagttga tataaaaccc caaaataaac ttagcatctc caatgtttac
      721 acatatacaa tgctcttaaa attgcagtga acgcgcaata gtgcaattga taatacttat
      781 tatatattct caatgcctta tatttcaact gctaaacctc aatttgtcac aaatatcgct
      841 cactgcaaaa tttctatatt tttattatat cataacatat aattaatatt ttcaattaat
      901 ttttacattt aattatgttt aaattctata ataatgcaac tttaatgttt ctttctggaa
      961 ctaatataaa aactatttca gaaagattag gtcatgcaga tataaaaata actatgaata
     1021 gctactctca gtttttagaa gagatggaca gagaagcatt tgaaaatttg agcaaaatac
     1081 tatttattat attttaaaga agatgactta ttcaatattt gatgctagaa tataattaat
     1141 aaaaatttaa ttataggtga ttgtattatg aatattatta aaagcataac tttactctta
     1201 acattattaa ttgtgatatt aatgacaggc tgttccccaa gagaaagtgc tagtgaagtt
     1261 gcaaaaaaat atattgataa gatgaactct ggtgactatg aaacagcata tagtttatta
     1321 agtaaagata gtaaaaaaaa aattagtata gaaaatcttg aagaatttca aaatatttta
     1381 gttagtacaa aaagaataat tagttataaa ataggtaaag aaaaaatcat aaaaaaatat
     1441 aaacatgatg gaaaagaata taaaaatgtt gttaaattag aagaaacttt taatataaaa
     1501 aaccttcttt ataaaaaaga tgattctcta aaagtaaata gatattttgt agttgaaaat
     1561 aacaaataca agctattatt gtatgaaagt ttcaaaaaag aatttggtat taatagtatg
     1621 gaccttgctc aacttaagct taatgatttt ggactaaaat actttaaaga agttgacctt
     1681 atactaaaaa aagctattgc tattaatcct actgattcaa agctttatta tgcccaagca
     1741 tgtaattata tgaattttga tggatttcct ggttattcag atacaacata taatgcttta
     1801 gattcaatta ataaatcttt aaagtattta gataaaaatg attctgacta caaaaaaaat
     1861 gcaagtaata tatataactt aaaaggagtt attcttatgt ttcacaaaag atttgatgaa
     1921 gcacaacaat atttaaataa agccttatac tttaacaaag ataatgaaga cccaaaatat
     1981 aatctaaata caataaaaaa acatctaaac tagatattta atttttgaat ttataaaata
     2041 tttttttatg tataattcag cactgaatca taatttctac taaactaatt acaagtttaa
     2101 attataaaga cttatttcta tataaatatt actctataac aataagtttc ttatttaaat
     2161 tttaaaatat tatctaaaaa tcataaaaaa gaaggtataa agagctaccc tcaagctcaa
     2221 tataccttat aaatatctaa acttcatttt ttactaattt ttctatatct ttgataatat
     2281 gttctttaga tttttttcca gctatggcat caaaaattgc aacagccttt ttctctccaa
     2341 acttttctgc tacatcatta aagtctaaaa atctaacact ttcttttggt ttaccaaaca
     2401 tataacacct ctcatacatt tttatatatt tattataact tctatagact tatttttcac
     2461 caataaacgt tagacaaatt agtcccttta tttttttaaa ctagctttac cttcaaaatt
     2521 cttaacaaaa acagtttatt ctactctata aataaaaata gacaatttaa tttgtaggaa
     2581 actgataata gaatacagta aataaaactt tgtttaatct atctgaaaaa gttatctatt
     2641 aaaactgcta tgaatttata aagaatattc tagttcataa aaatacaaat atgtaaatat
     2701 aatcacctta atattcaatt tatttaaaat aaaaaatgta taaaagattt aataatgaca
     2761 atatactatt ctcaatacaa tctatgatgt aaataattta aaactactat attatttaaa
     2821 aatttatatt tatatatgca attctaaaaa cttaataaga agtgaactta gaaaataaag
     2881 cttaatttca aagacttaaa tagactatta ttattagtct aaataaacta cgtctatcaa
     2941 aattatatat taaattcttc taaaattttt attgcaaatc ttgcgtttgg atatgtaata
     3001 gacccgccac caattacacc tatttttata gcttctataa tttcatcttt acttgctcca
     3061 gaattaatac aaccctcaat atgataacaa atacactcat cacatcggct taaaattgaa
     3121 atagctagtc ccattaattc cttatttttt ttgcttatag ccccttctga ataagtctta
     3181 tcatcaagac ttccaaatac tctaaaaaac tcatctgttt cgcttaattt tttattgtaa
     3241 aatcccctat attctttcat ttctctagta ttcatcttct acctcctatg tttttcttat
     3301 aagaatatca caccgtactt atattttcaa tattaaatac aaattttcat tttatgttca
     3361 ttagcctaat ttatattatt ttttgaaatc tcaataagtt atcatataag taagattttt
     3421 tcagaactaa aatagaaatc ttagtaattt ctttattatc tatctcagtt ctgaaatata
     3481 ttattcttat ccaaacatta ttatagtgat taattatatt agttattttt acctgaaatt
     3541 ttatacatca aataagaata tataaatggt agtattacaa ttacaaagat tacaaagata
     3601 ttataaaaag gaatattaat aaatgcatta ataattaata atattccacc aataagccaa
     3661 atccatccag ctaaatggtg tgtcttattc caattatctt catcattaag agtccatggt
     3721 aaaattattc ctactgagta atttcgttta catttaggaa gatagtttcc aaataaaata
     3781 actattattc ctaaaattaa tcctgtataa aaattagact ccaaactaac tcctgttgaa
     3841 tataaaacca tcattatttg tataattact gaaagtatag caactcccca ttttgataaa
     3901 ttttgtataa catttgaaaa attagctttc ttaggctcat tctcaagtct aaaccatgta
     3961 tacaaatgga tacatagcat taacaatggt acaccaaaag ctgctataac ctttggagca
     4021 taattatctg gatttccata attatcaaaa tgaattgcaa cttcatttgg taatctatta
     4081 taaaaatata ttgatacaat aaatggtata aaacatatta aagtagataa aataaattgt
     4141 ttatttatcg cttttttcat tatctttttc tcccttctcc ataaattgtg aaaaccaaag
     4201 catgacctct tcgaaaactg aaatatttat ttcgtagaaa ataaagttct tatactttgt
     4261 ttcaaatatg agtcctgcct tttttagttg agatagatga taagaaattg tagcattcgt
     4321 catattaaat ttttcactaa tttctcctgc tgacatttta ttctccctca acataaccaa
     4381 tatttctctt cttatagggt ctgaaagagc tttgaatgtt tctggaaacc ccaacaccat
     4441 cacctcgcta tttagaattt catctaaata gaatataaca taacatccat tttatttcaa
     4501 tagctattta gaaatttttc taaatagtta tttctaaata tttattgaaa atttttatat
     4561 taagattctc aatttactta agtcgctttt atttaatctt actttatcta atttttttaa
     4621 cttaacaaaa gtgtattgca ccataattgt taaagcaaaa acctaatgat tgaggtactt
     4681 atatatataa caatactttt aattttaaat taaaagtagc taaacccaat ttaaaaagta
     4741 gttaagtcct atttaaatag aaaagaatga aacgagaaat atactgtata aaagtacata
     4801 aaaacatcta ctaattagat acaactataa cagaatatat ttattattat aataacaaaa
     4861 gaataaaaaa aattaattta gcataacctt gttaaatata gatttgaata tgaatttaaa
     4921 gttatgtaaa attaaaaata caggaatgaa aattccattc ctgtataaaa tctaactttt
     4981 gagtctcagt acaatcttat tttgagacaa tcttttttgt tttatatttt cttatattta
     5041 aaatataacg catatcttat gcaacatatt catatttttc tttatattct ttcatcgcat
     5101 cattccaagc gtcttgtact gttacacctc ttttattagc aattttttgt gccagttcaa
     5161 ttatcttcat agctcttctt gatatgttca taaacattcc tcctacaaat taccatatat
     5221 ttcatatata taaatcaagg ttatattttt atgatatata atccttctat tgtaagatta
     5281 cagtttatat gtgtattata tatgaactat attagaagat aattagaatt tttataaagc
     5341 tatatgatta gattaaatat aaaagcttta caattactta taaatttaaa aagtctataa
     5401 gctaaactaa tgtttgatat accaatttta cgaccataaa taatgccatt actaaaaata
     5461 ttggttttat catctttgaa cctttcttta tagcaacttt agcacctaca taagctccca
     5521 ttatcatcac taatgcaaac actatagcaa ttttataatc tacttgacca tttatcatga
     5581 ataataacaa tgaagttata ttacttgtta agtttaatat ttttgtattt gcagaagcat
     5641 gtaaaaaatc atatccatat atttttataa atccaaaagt caaaaaagtt cctgtacctg
     5701 gaccaaaaaa accatcataa aaacccatta taagagccat aagcatccct aatcttaaat
     5761 ttttcttatt aacagcttca aaattatctt cttgacctaa atttttagaa ataaaggtgt
     5821 aaatagccac tattaaaatc ataaccacaa ccaaaacatt taatatctct tcacttattg
     5881 ataatacaca tctcacacct agaacactac caataatagt aaatggtact aattttttta
     5941 aaaggttgtt attaattttt ccagactttg catatctata ggcactactt atacatcctg
     6001 ctgatgctgc aaatttattt gtaccaatgg caagatgtac tggcactcca attgccataa
     6061 gaacaggcat gcttataagt cctcctcctc ctgctataga atctacaaaa gcagctaaaa
     6121 acccccctat acataaaaaa ataactgaaa acataaaatt cctccatcat tctctttcaa
     6181 tttttcttac aatatatatt atataatctt atttaatact tattatccag catattcttt
     6241 ctatattcat ttggagttat actattaaac ttcttaaata tttgtgaaaa ataactactg
     6301 ttattaaaac ctactttctt acaaatatca ctaatactca tgcttctatc taacagatat
     6361 tttttagatt cttctatcct aagaagattt atatactcag ttattgaaac tttatttctt
     6421 tcattaaaaa tagaactcaa ataatttgga cttataaaaa aaacatctga tatactattc
     6481 aaatttatat tttctttata atattttttt atatattcgt ttatattttc aattagattt
     6541 cctttatctt ttctccaaaa tgctctattc ttatcaatac actctttgga aaattcaaat
     6601 aatacattcc ataaatcttc atcactgttt acaagtgata tttttttatt atatttattt
     6661 cttaaataag atataagttt taaatcctct aaatctctaa gcactgttct agacaataca
     6721 aatatcattt cctgaatagt atctctaaca tcattatatc ttaatttgtt tgtatctatt
     6781 agattataaa caccttctaa attcatattt ttaatttctt tttcaatata aagttctaat
     6841 tcaaagggat attcttttga agaattattg aacatatcta tcggattaat aatatactct
     6901 tcttctaata atctactatt tgctttttta agtgcctctt caagtcttat attttctttt
     6961 ctactcttca atatctcctc atcttttata ctaagttgat tttcaaaaaa attcctctta
     7021 gctatttcct gaataaattc agacatcatt aataaatttt cttttaatac atataatcta
     7081 cttttaggat ttaatggaaa ttcattgtaa attttgttta tgtattttat atcaatacca
     7141 gaactacttg ataattcaga taaattttta tctatatcaa tagacttata tactataaaa
     7201 ttaccacatt ctatatatcc aactatattt tcttctaata ctataggtat ctctaaactg
     7261 gaaacaccat actcacaatg gtacactttt tcaaagttat cattatttat gcttttaaca
     7321 agttttttag tacactgttt tatattttta caaatatcgc aaaatttatt ttctttctta
     7381 gtctcaaata tttctttata ctttaagtca tatacagata ttctaagctt caatatatta
     7441 gatatttgat ttgcaagatt ttcaattatg tttacattaa ctaactcctg tatattgttt
     7501 tcagaaaata ctataggtat ttgtctcaaa ctcgaaaatt tatgaggaac ataagtaatt
     7561 aatattacta aatcaatttt accagtgttt ataatttcat gttctgaata tggtgggcaa
     7621 taaactatag atgtttcctt tatattgacc tttttaccat caattatttg tattccttct
     7681 ccctgaatca catataaaag ctgttcttca cttaaatgaa aatgcttttc ttggtagttt
     7741 cccggaaaaa atcttacaat tccagcacta agtctattga attgtgtttt tgatggttcg
     7801 tgtatccaca taacctctcc ccaatcaaat ttttgtactt cattatttga ctcactaaaa
     7861 tactccataa gctcacctct tagtttttgt ctaaatattt tttcttccct tcttatatta
     7921 aaataatatc atcatcatta actttcatta ctataaaatc atcatactct tttaatactc
     7981 ctgtaatttt agttgcactt agtttactac aattcagttt tttaatatat tgataaattc
     8041 tataattact tttttatttt gtaaaatcag tgttttccca aaataattat atctataaat
     8101 gaaagtattt ttactgctta catcaatata tgttatcata attttccttt ttattgcata
     8161 tataaataac tgtatataac attgtccaat actatataga aatacatcta agaaagaata
     8221 ttattaaatt gttccaatta gtattatttt tcttatagaa ataaaaaaac tgttggagtc
     8281 ttttagaaaa attatttttt acataccttt tttgcttaga tagtctatct tcacagctat
     8341 tttgtatata cactcttcta gttcatgatt ttattttaat atcttgctta tattgctgaa
     8401 ataattgaat tcttttatct atcatattgt ctcttatatc acaaacatat tgtttcttat
     8461 atcacaaaaa tgaaagcatt cttatatctt caatatataa acctgctttt tttaatcttg
     8521 taataaatat aggatactct atattctctt cctagaaata actaatacca cttatttttc
     8581 tattatatag aaagtaataa atctttttct taataaaatt caatagtaag tggaataaaa
     8641 ttttatatga ataagaacat tataaaaata ctttatacaa tagtcaataa aagatattag
     8701 cttcaaatta tgttaaagtt gtattattta aagtgaaaaa acaaataaaa aagaaataat
     8761 agtataagta gaaaaatata cttaaaacaa ggcgaagcct ctcttgtatc taaatcaagt
     8821 agagaattaa atctaaaaaa gaaaataaat ataaaagatg actcctgtac attacaagaa
     8881 tcatcttatg gtttcataat cactccatgg tttttaactg tctgatataa aggtctcagt
     8941 tcactcatag catgaccacc ttttccgatt gctgaccccg tcacttatgg acaaaatgtc
     9001 cataagtgat agtcctctct taaaaccctc taaatagata tatctcaagc accgcattga
     9061 aaccagttgc tggaaacaaa ctgaagcgtt ctggaatagt aaaagaaatt gccaccatat
     9121 ccacgttact gtcctagttg ttactttgct aacttcggag cgatttcctc taacaatacg
     9181 cagtcaaatt ctgccttttt gctaagaaat ggcagatggt ctgcatctgg tataaaaaaa
     9241 atctgtttgt ctggcgccac tatttcatca aaaaatttct tcgctggaag ataggggcta
     9301 ttatagtcat tttctcccat gatgtagtat acagggacct gatagtcaac tccataattt
     9361 cttatgtcag cttcttccac taaaaaccgc aatacatcac cttgattgtc aatcgcattt
     9421 ggattgaaaa tggccgtatt ttttaactct ctcaatgaat aatacggggt tgccagtata
     9481 ctgattatat tgcccaaatc catatttata gaaagcccat acttgctttg gtatgttctt
     9541 actgtcataa gagctgccaa atagcttgga ccatattttg ctggcggata tggtgcaata
     9601 gcttccagcg ccttgatatc tttttgcttc cctgcagctt tcaccatttc aagtgtcttt
     9661 tcatagccca cgcgctcatt gtccaccata ttaacggtct gcgcaatccc aatgtacgcg
     9721 ctgtaatcct ccggataggt ttgcacagcc atagttccca gaactgttcc ccagctatga
     9781 cctataagga taattttctc cttgttgaac tcttgcttca aatatgctgt cacctcatgg
     9841 acgtcttgca gaacacgctc cgcgctcatg gtctgcaaaa ctgctgccgg atcgttcgca
     9901 aagtatgttt tgcctacgtt tcgctgatcc cagttcacca cagtaaaatc attttcccac
     9961 tcatactggt acagatgtaa aaatggcatc attgaattac caggaccccc atgaacccaa
    10021 aggatgatgg ggttgtctgc gttttgtccc cggatatata acgcctgctg tatgccgccg
    10081 atctccacca tttccatgcg gtcgattcca ggagcttcta ttttatggct tgtacgtata
    10141 atcgtggggg ctatcagacg caaaccggca aacgccagaa caaaaacagc aactagtatg
    10201 caaagtgtga ttaatatcat tttaagtacc ttctttcatg aattttttta gccatagata
    10261 tctcctctaa cattaaaaaa aatatgttgc tattttagtt ttgttactct acctgtccca
    10321 ttggtttcct ttcataaaaa atattaattg attctataat ctcatcttcc aggatatcaa
    10381 ctcctatttg tctcataaga aactgtaaga attgaaaccg tttacgaagt gtaggaaagt
    10441 ccccctgaaa tacatctgta tcacaccaaa agttaaagag cagcaaaatt acctctgcgc
    10501 attcatctgg gaactctgtg atgatgcttc tatcctctat gccttctcgt aaaacatttg
    10561 ctaatattgg tgctagtttt ttcaaattat cctgtgtaaa tgccagtatg atatgcggac
    10621 tttctatcgc gcttgtaatc atgttactag attcttttat cacctcatcc gttaaatgcc
    10681 gcctaactaa acttctaagc ttctcttttg ctgtaagtcc atgcatttca ccgagccatt
    10741 gatttactgt ctctattatc tgttcaaagc gcctttccat gaccacatta aaaatatctt
    10801 cttttgaact gaagtgatga aaaattccgc cctttgacat tcctgaagca tcaacaatat
    10861 tttgcatact tgttttgtca tatccttttt cagcaaacaa ctttgcagaa atggtaatga
    10921 tattttcaat agcttgcttt ggattgttct ttctagtcat tatataactc cttcttatta
    10981 aaaaccgact gttggttttt attatataag ctattcctgc ttctgtcaag taacattgtg
    11041 tttatggcaa aacaataagg tttggtggtt agacaggtat taattagact aatgcgactt
    11101 tcccctagat ggaacccttg gtaaatttgc aatctttacc ggctttgatt atatctgtaa
    11161 gcaaggcagg tatggccaca cctgccctgt ttgcccctcg gatattcatt cctatccctc
    11221 ctctccttag ccattacacc aaaacgccgc tcattgtctc caatggcggc gttttaaaga
    11281 tatgatttct catgctgctg aaatatgcaa aaaatataag atgcccttta ttatttttcc
    11341 tacaatagaa aagaaaagta ttgaagaatg ggttaatatt ggagcaaata tgctttgttt
    11401 ggcacaagat actaccttta tcacttatgt tatcaatcaa ttattatctt tttataatga
    11461 gattgtacca attcaaaaac aacattaaat tataaatcta attttatatt aaaagagact
    11521 aatattttat ctatctctat taaggatatt ttcttatgta tcataatatt agtctctctt
    11581 attattatat actgctatca tcattagttg ctatttatac tatttttata atatacaaat
    11641 ttattcagct aacgttttgc ctaattctat acactcatct tttgcttctt catttgggtc
    11701 ttccattgct gtaattcctt ctccaccaat aattgtagca ccagcatttt gcatacgttc
    11761 ttcccagtct ctcatccatt cacaatttcc ccatccatat gaaccaaata atccaatctg
    11821 tttacctgat accatagatt ctaattctga aacaaatggc tccatatacc cctcttctag
    11881 ttgctctgct cccatagatg ggcaacctaa tgcaaattta tcttcttctt ttaaatcact
    11941 tggtttcagt aagctcacat ctaaaacttc tggtgtctta ccttttaact tcacaccttc
    12001 agccacaaaa tttgccattt tttcagtatt tcctgttcca ctccaataaa caatatatat
    12061 tttactcatt tttacctcct gtagtatttt ttaattaatc aatagttagt tatagctaac
    12121 taacatctaa aaaacaaaag atttctttat ctgaaatctc tttatttttc taaatataga
    12181 atatcatggt tgattttgaa attcaatact tattgataat atttatcatt tatattttat
    12241 attcatttta taatatcaaa acactgtatc gtatttctaa tctttcatag aaaaatttct
    12301 aacttatagt acttttgcat ctcttataaa tcttttatat gtataagtac atagaaaaac
    12361 acaccttttc cagatgtgct atctataata tcgtatattt atttttcaat tctaactagc
    12421 taatatgttt ataaatttta tcacttaata cctttataca ttgatgtaaa atcttacacc
    12481 taagtaattt ttattatttg tctcgactct atataatata gctattttat catcaaatca
    12541 aaaattatct tttgctatta ttcttgtatt tataaagatt taaatataag tatccatttc
    12601 cttgttccgt tctaggtatt ccaagcgctc tcgtacattt tattaattgt gcatacagtt
    12661 cagcttcatc taaatctctt tcaaactcct ctcttgccca ttctttaatt agtgctaatg
    12721 agcctgatac gtatggtgca ctcatactgg taccactcat aatagcaagt ttattatcca
    12781 tataagtcga tataatattt cttcctggag ctaccaaatc tattgtagta tttgaattac
    12841 taaacttttc aaccaaatag ttctcattta ttgcacctac ttctattacc tcagcataac
    12901 tggctggata actatactca cttgtactag aatcaccatc tccattatta cctgctgcac
    12961 acactacaga aatattattt tttactgctt gcatgacagc attttttaaa ttcttatcat
    13021 ctttgtttcc cccaagagac atagatataa tatcaacctt gttatttaca gcaaagttaa
    13081 tagcattaat tatactttga tatgttccag taccatcttt atttaatgct tttgctatta
    13141 ataatttaca atctggagct actcccataa cttcattatt ataattagat gcagctataa
    13201 tacccgccac atgagttcca tgaccattaa aatcctcata tatattttta tttccattac
    13261 tgtcatcact aaaatttgca ccaccaatta tttttccttt taaaagagga tgagatatat
    13321 cacaacctgt atctattata ccaactacaa tatttttacc agtataacct tcatcccaca
    13381 ttcccctagc attcatttgt tttattccat atgggaattt attttttgca cctcttagat
    13441 tttcatttat ttcatatgga attagtttca ttcttttatt catcatatat cctcctaaaa
    13501 attttattgc ttataaaaat catgaatttt attttataat aggtttataa atcaaattaa
    13561 aacctatatc tacttattta tatttatgat atatttttta tttttaggag tcatatttta
    13621 ttgtatataa aataatattt agataactat attaaaaaat acatgtttgc ttatatacaa
    13681 aacttactaa aatgtcttta atatttttgt atacaaacat tatatttttt atataaaaag
    13741 ctcataaaaa ttttgattat attttcataa gttaacaaat gtgggtataa tatgaattta
    13801 caaaattcct ctgtttgtat aagtgcttta ccaatacaac aatatataat cacattgaag
    13861 ctatatttgt atttatagta gataatgtat caaaaattgg ttatgaatag taaaaatacc
    13921 agttaagcat attttcatgt ttctattttt aacattaaat ttccaatctt catatgtata
    13981 tttttaacaa aggtgtttac ttatttaaaa actctaaaac tctttcatta aaatcctgtg
    14041 cttcttcata tgtagcgtgt cccaatccct catagataaa tatttcgctt tttttaattt
    14101 tttctactaa atgaaaagaa gcattatttc caacaatttt atcattagca cctcctataa
    14161 ttaaggttgg acatgttatt ttatttaatt cggaaaaggc attatgttct atgcaagagg
    14221 tcgcttgaat aataaatcgt ttaaaatcct ttggtttacc tacttttcct aaaaaaggaa
    14281 taaataattg gtattttttt aaatatcttt cagaatagga tttctttgct gtgtcaatca
    14341 ttaaatcatt gtaattctgc ttcttcgcca tatcaatcca actacaaata acattttgga
    14401 tagtatcatt ttgctttgaa gaagtaactg ccaacacaag tttctcaact aactcaggat
    14461 aatcaattgc cagatattga gctatcattc caccttgaga aacacccatt acttctgctt
    14521 tcataattcc aagttttttc attatatctg cttggtcttt agccatatcc cttgtggaat
    14581 atttttctgt aatttgattt tttctactaa atacataaac cttataatct tttgtaaatt
    14641 gcttatatct aaaagcaaaa gcaatcgcct gtatttttcc atgtaaagga aataaaccat
    14701 ctcctaatcc tggtaaaata attagtgtct tcttaccact accaaattca atataattca
    14761 ctgtattact tcctatcatc atttgacaac tttttgcatt ataaaacata gtctattcct
    14821 cacttttcct attatcattg tttaaataaa tctttaaatt tttgaatacc atactcatca
    14881 attagaggaa tatccatttt ttttaacatg aataataaaa aatccaacct attacatact
    14941 tcactgtatt cacgtttaaa taatacaggg tcaagtaaaa tatcaatact aaaaacgagc
    15001 atttcagcta attcctctgg atattcacaa gaaaattctt tattttcaac accttgttta
    15061 attatcttag caatattggg tgcaactaca ttgttgagat tacgaacttc ctctattaaa
    15121 gcgaatggga ttttttctaa ccagctacaa tgtaccattt ttctacgtgt gtaatcattc
    15181 gcactatgaa caaccaattc tattattttt tcatttgctg taagggtgtc atcagcaaca
    15241 agatgctcta aaaaattatt catttgtgag taaagttctt ttgtgacact tctcagtata
    15301 tcttctttag ttttaaagtg atgatacatt gcacctctag atagaccaga taaattgata
    15361 atatcttgtg tagatgttga atcatatcct ttagacgaaa atagtgaaaa tgctgattgg
    15421 ataatttttt ctttactatt tttacttttt tcttctctat tcatatttcc ctcctaaaaa
    15481 cagactgtct gtttgttttt tattatacat tttaatattt attatgtcaa gaattaactt
    15541 actttcaatt tcttcatagt tcagaaggaa cgaaaagcat tccacatcaa acttttaaaa
    15601 agttgtatta cctcaacaag gtctaaaaga tacatctcta tgctgtactc gtattcctta
    15661 taatagagat gtattgtttt caaagataat caagattttg ctatgttttt catacaaaat
    15721 aaaaaggata cctcattagt gctataacac ctaagatatc caattaatat tttcttaact
    15781 ttttctaatt tacataaata tagtctacta ttttaaaact gctcctgtat ttgctgatgt
    15841 taccagttta gcatatctac ttaagtatcc atgctttatt ttcggttcta aaggtttaaa
    15901 ttttaatttt ctattttcta tttcaacttc atctactttt aactctaatt ttttgtctgg
    15961 tatgtttata gaaattatat ctccttcttc aactagtccg attaaaccac cttccatagc
    16021 ttctggagaa atatggccta tggatgcccc tctagttgcc cctgaaaaac gaccatcagt
    16081 aagaagtgct acatgcttat caagtcccat tcctgcaact gctgatgtag gagatagcat
    16141 ttctttcatt cctggaccac cctttggacc ttcatatctt ataactataa catcaccttt
    16201 gtttattttt ttaccaaaaa tagcatttac agcttcttct tctgaattaa aaactcttgc
    16261 tggtccttca tgaactaaca tttcttctgc aactgctgac ttttttacaa cagctccatt
    16321 tagagcaaga tttcctttca atattgcaag cccaccttgg ttactatatg gattctttaa
    16381 tgtatgtatt acttcttcat tttctatttc acaatttctt atattttccc ctatagtctt
    16441 gcctgttacg gttttgcaat ctaaatttat tccatttatc tttgaaagtt cgttcattat
    16501 agctggtatt cctcctgcca tatgtaaatc ttcaatatga tgttttccac ttggacttaa
    16561 ttttgttaaa caaggagttt tttcacttat ttcatcaaaa aaatctaagt taagctctat
    16621 tcctgattca taagctattg caggtaagtg aagtactgta tttgtagaac cagccattgc
    16681 catatccaca gctatagcat ttttaaaagc atctattgtt aaaatatctc taggttttat
    16741 gtcgttctta agtaactcca taacatacat acctgcatat tttgctatcc tttttctttc
    16801 tccagaatgt gacgcagcag taccattata tggtataccc atgcctaaag cttctgttaa
    16861 acaattcatg ctatttgctg tgaaaagacc agaacatgaa ccacatccag gacaagagtt
    16921 catggctaac tcttctaatt cttcttcact tactgttcca tctttacatg ctccaacacc
    16981 ctccattgca gagttaaaat catatacttt tccatttttt ttacctggaa gcataggccc
    17041 tccactcaca acaatacttg gtatattaag tcttgcagca gccattaaca tacctggcac
    17101 tatcttgtca caattaggta taagtaccaa agcatcaaaa ccatgtgcca tagccatagc
    17161 ttctattgaa tctgctatta attctcttga agccagggaa taattcattc cgacatgccc
    17221 catagctata ccatcacata cccctatagc aggaaattct aatggcaaac caccactcat
    17281 tcttactcca ttttttgcag cttctgctat ttcatcaaga tgcagatgac caggaatcac
    17341 ctcattttgt gcatttacta tacctattaa tggtctttca atttcttctt tagtaagacc
    17401 cattccatac attaacgctc tctttggagc tccttctatt ccttttttta tatcacttct
    17461 cataatatta cctctttctt acttttttaa attttcataa tattattata atatattttt
    17521 ctattaatta attacgaaaa ttgtaaaaaa atattagcat atactaatga aaatttatta
    17581 cgatttttta tcaatatctt acacaatcgt attatataat attatctttt caatatattt
    17641 tataaactaa tatattttac aaattgttga gtaatatttt atgatataaa tcagaagagg
    17701 cacttctata atagaaagtg ctcaactatg aataagatta ataatatatt tgccttagat
    17761 atatagactt ttataaatat taaagattaa tcaaatctga tgtttgaaac tttatcccaa
    17821 ttaatcttcc ttgaatagtc ttctggatgt gataatctaa ctatatgagt tgaattatca
    17881 tagctgtaat aaattgtagt agtaccatca actggattct ttttgtatcc ttgatacaca
    17941 gcactatttg gtactttctt ttcaacaaag ctatatgcag atgaagtatc aatagtttct
    18001 attttattag gaaatataaa catataaaaa gctactacta taaaaataca tatgcatgta
    18061 atactatacc atttaatcca tttcataaaa ttcctcctac tttaccaaaa tatactatta
    18121 ttatttccat atatttataa tatttatgca tacgataaaa tttttatatc cctaactata
    18181 taattgtaga aactttgatt atatatattt tttaatctta ataatatatt tttataaatt
    18241 aataaatttt taagatttta ttaaaagatt tttaaaactt acagtttaat ataaagatag
    18301 tacttataaa actaaaaaca taaatttgaa aggggacaaa ataaaatgat atggacattt
    18361 tattcattta tttgcgttat attaccatgc ttaatatacc aaatagtcgt tataaaacga
    18421 aaaaatttga aagttgaaaa gaatgtaatg atacatttag tatgggtata tattttttta
    18481 ttatatatct atctagcact tagtaaagct ggaattggta gcatatggga tataggaagg
    18541 tatagtgggc tttttagaat tgatgaaata aatctaatac cttttgactc agttggcatc
    18601 ttaacatata ttttaaatat aattatgttt atgcctttag gatttttact acctttaatt
    18661 tggaaaaatt ttagaaatat tatcaatgtt tcattaactg gattaggttt ttcattagca
    18721 attgaacttt gtcaattgtt taacttaaga gctacagata ttgatgattt aatgatgaac
    18781 acattaggtg ctgttttagg atattttata tgggtaggtg taaataattt atttaatctt
    18841 ataaagaaaa aagatatttt cccatctata tataaaaata ttattcaaga tgagattgct
    18901 attacaattg atgatgacat aagcaaaaaa attacctctc tttacaaaaa tgaagctatt
    18961 atatatttaa tacttgctgt tttaggagaa tttttattgt ttaattggtc cattatacct
    19021 tattaaataa tttattgata aaataagtgt acttcgatat ttacaaatat gtaaagccct
    19081 ctttcatact acaaaagaaa gtgggcttta gttattaaat taaaatgcac actcactatt
    19141 tagctggcat ctgaaatatt ttattaacat tgtatctgac tttatttgat gttatataat
    19201 catattttgt tccattttca atgaagtttt gtatattgtc caacacttgt atagctcttg
    19261 tattattttc ataatctcct atttttacag tatcaatttt actttcaaat actgcataaa
    19321 cttgactacc atctatttta atttggttta tctgcattaa attagtttta tcttgacttc
    19381 taattattat catatcaatt cctccattta cttaattcat tttaatttct aataaataat
    19441 attttataat tgatttatag attatttaaa tttttaaact tagtatttta ttttttaata
    19501 cgattattta tatcaattac atctctaata aaaaattttc ttaaagaata cttttttgat
    19561 aatactttgt tttatttgta gattgcattt ttgaccatta taactaaatt aaataatcta
    19621 atgtattaaa acataaaatt atctatgcta ctgatttatt ttatacattt ggtaatttta
    19681 cttgcaaaaa attttgtaca tattgtttat atctcaatta aaggttttca aaactttcta
    19741 tgtatttatt aattaattca gtttcttatt tcaacatacc acctctcatc aaattaccat
    19801 ttgtataatt catattatac atatacaaat ggtaattttc aatatatttt attattttaa
    19861 cctttttttt ttatattttt ggtaatttta ttttactttt tatcaaaata acttataatt
    19921 tcggtaagga gtgatgtaca tatggaaagt ttaggagata gaatagcaaa tctacgaaaa
    19981 gaattagata taaatcaaaa agaacttgct actaaagtcg gtataactga ggctagcttg
    20041 tcacgttatg aaaataattt aagagaacct aaaagtgaaa taatagttag attagcaaaa
    20101 gcattagaaa catcaacaga ttatttatta ggcgtaaatg ataatacaaa aataagcaaa
    20161 gaagataaat taatcataga gaacttatca gtaagtgaaa aaacaaaaaa gctcttagaa
    20221 aaaatatatt ctcttgaaaa agaagataga gaagctatag aaaaaatgat tgataatgcc
    20281 tatttaaaaa gattccttaa agaagagaat taattctctt ctttttcttt atacaaaatc
    20341 tcaagtaata attcataaaa agtaatatct tcactcaata aatgttctaa tttcattcct
    20401 atatcttcaa ttttttcttt ttttgtaaca gtagtgtttg acttttccac atataccatc
    20461 ccccaacaaa cttacgttct taatgttagt cagaaattcc caacaaattt ttaataaagt
    20521 ttatgtaatt gtattttgat tttataaaat atattttgat tatccaaaat ttccctagat
    20581 aattatctta attatataat aatactttta ttctacagtt gcaataaaaa actcgtaata
    20641 ataacaaaaa aatctattat tgtagaatct tgtatgtttt ttctattttt atatattttt
    20701 caggatgatt tttattataa aattttttat aaatatataa tttttttata tttatttgac
    20761 tttcttttaa ttctttagga tggatttaaa ttttctataa aaatcatact attttagctg
    20821 tttacttgct tatttaatag ttttatttct ttgattaaat atctttcaga atctaagcca
    20881 gatgtctcaa aaaaactgat ttataatata atcatttttt ctgctattct tatttttcca
    20941 attttagttt catattaaaa tatacttttc atagacacta cattctttca tactcatttt
    21001 cacatttaac tatacaagta gtcttactca tttatgtact atactttatt aatatttatt
    21061 aagaaaaact caaagattta aaaatatata ttttctataa agtatattta tgaattattt
    21121 catatcttct tttaaaataa cattactaac ttctttatgt tcatttctat acttagttgg
    21181 agatatatta taattccttt taaataagcg actaaaataa tttatgctat caaagccaca
    21241 tctcatagca atttctgtca tatttaaatc tgtttccttt aaataatata tagctttatc
    21301 aagcctgatt ccatttataa aatcgattgt agtcttacct gttatttgct taaatgttct
    21361 acaaaagtga tgtgcactca agttcacatg actagcaagt tcttttaatg taattttatc
    21421 catatatttt tcttctatca aatcaaagat acattcaaat ttttctaaag aatactttct
    21481 ttttataaat tcatcttcag aatatatttt atcaatatga cttcttaata agagtactat
    21541 taattgatag atattagctt ttatagataa ctcatatcca acttctttat tgtgatattc
    21601 atcaagtata gttgtaatac attttaaaat cagagaatca ttttgaatta aattattaaa
    21661 tacaatatga tttaaagcca atggtgctaa gtacttggtt tgtaacaaat caacttgatt
    21721 actaaaaagg aatgtgggtt caatacgaat actatagaat tttaaattat ctgataagct
    21781 ttctaaataa tgtaattcat tactgtttgc tattacaata tttccaggca ctaccttaaa
    21841 attatccaat ccacattcaa gatatgctat accatcaata aaataatata tttgtagatg
    21901 ctcatgccaa tgtcttttaa agtttgctcc ttttttaatg tcatccttta aaaaaatatc
    21961 tataaagttt tcttgacctt tcctgttaaa atatgtattt ttatccttca ttattccccc
    22021 ctcatcaaaa tagtgctaat tataagcaat atagttattg tattcattat ttcatatcgc
    22081 tattatataa aatgtaacta tcattgtaaa cattaacata atgcagtcat tataataagg
    22141 aggtaataaa aatgacaaac tcttttaaaa aagatgataa tagaaaaaaa atcacagttt
    22201 tatttgtagt cattgccatg acttttatgg caacattaga ttctagtatt ataaatgttg
    22261 ctctcccagt tcttgcaagc aaactaaatg tatctctagc atctattgaa tgggtaatag
    22321 caagttactc aattattatt tgttcaacac tattattttt tggaagactt ggagatatta
    22381 ttggtaaatc aagagtattt caagtaggta ctattctctt tacatcagct tcattactat
    22441 gtggattaag taattcttta actttactta tagtttgccg ctttattcaa ggaataggcg
    22501 cttctgccta catggcaaac aatcatggaa ttatcacaga actatttcca aaagaaagca
    22561 gaggaaaagc cctagggatt ttagttactg cagttgctat tggaaatatg gttggaccat
    22621 ctgtgggagg atttattttg tcaatatttg attggaatgt tatatttttt ataaatattc
    22681 caatcggtct tattgtaatc tttttaaata caaaatttct tcctaatagt aaaaaatctt
    22741 cagaaaatat ggataaaact ggtgctatac ttcaattttt aggaacaaca ttatttttta
    22801 gtgctctaat tagtgctcaa caaacaggat tactaaatcc atatatatta attgcactat
    22861 tattatcaat tatttt
//
LOCUS       DAYAKB010000055        22775 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.055, whole genome shotgun sequence.
ACCESSION   DAYAKB010000055 DAYAKB010000000
VERSION     DAYAKB010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.055"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            29..2206
                     /locus_tag="ACGI3L_002585"
     CDS             29..2206
                     /locus_tag="ACGI3L_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HFG9198283.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYKQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEANCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2220..2642
                     /locus_tag="ACGI3L_002586"
     CDS             2220..2642
                     /locus_tag="ACGI3L_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9198284.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            2816..3391
                     /locus_tag="ACGI3L_002587"
     CDS             2816..3391
                     /locus_tag="ACGI3L_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9198285.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEINKSKHIPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(3516..4232)
                     /locus_tag="ACGI3L_002588"
     CDS             complement(3516..4232)
                     /locus_tag="ACGI3L_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9198286.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            4397..5122
                     /locus_tag="ACGI3L_002589"
     CDS             4397..5122
                     /locus_tag="ACGI3L_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198287.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASFLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            5182..6774
                     /gene="hcp"
                     /locus_tag="ACGI3L_002590"
                     /gene_synonym="priS"
     CDS             5182..6774
                     /gene="hcp"
                     /locus_tag="ACGI3L_002590"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HFG9198288.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            7146..8051
                     /locus_tag="ACGI3L_002591"
     CDS             7146..8051
                     /locus_tag="ACGI3L_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9198289.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            8175..9128
                     /gene="msrA"
                     /locus_tag="ACGI3L_002592"
     CDS             8175..9128
                     /gene="msrA"
                     /locus_tag="ACGI3L_002592"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFG9198290.1"
                     /translation="MIKLATFSGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            9281..10411
                     /locus_tag="ACGI3L_002593"
     CDS             9281..10411
                     /locus_tag="ACGI3L_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9198291.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(10528..11496)
                     /locus_tag="ACGI3L_002594"
     CDS             complement(10528..11496)
                     /locus_tag="ACGI3L_002594"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFG9198292.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            11831..12019
                     /locus_tag="ACGI3L_002595"
     CDS             11831..12019
                     /locus_tag="ACGI3L_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198293.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            12279..13478
                     /locus_tag="ACGI3L_002596"
     CDS             12279..13478
                     /locus_tag="ACGI3L_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HFG9198294.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            13530..14033
                     /locus_tag="ACGI3L_002597"
     CDS             13530..14033
                     /locus_tag="ACGI3L_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFG9198295.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            14140..14457
                     /locus_tag="ACGI3L_002598"
     CDS             14140..14457
                     /locus_tag="ACGI3L_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198296.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            14615..15574
                     /locus_tag="ACGI3L_002599"
     CDS             14615..15574
                     /locus_tag="ACGI3L_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFG9198297.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            15689..16474
                     /locus_tag="ACGI3L_002600"
     CDS             15689..16474
                     /locus_tag="ACGI3L_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198298.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            16766..18085
                     /locus_tag="ACGI3L_002601"
     CDS             16766..18085
                     /locus_tag="ACGI3L_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9198299.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(18160..18588)
                     /locus_tag="ACGI3L_002602"
     CDS             complement(18160..18588)
                     /locus_tag="ACGI3L_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198300.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(18679..20055)
                     /gene="hydG"
                     /locus_tag="ACGI3L_002603"
     CDS             complement(18679..20055)
                     /gene="hydG"
                     /locus_tag="ACGI3L_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HFG9198301.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(20056..21141)
                     /gene="hydE"
                     /locus_tag="ACGI3L_002604"
     CDS             complement(20056..21141)
                     /gene="hydE"
                     /locus_tag="ACGI3L_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HFG9198302.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(21177..22385)
                     /gene="hydF"
                     /locus_tag="ACGI3L_002605"
     CDS             complement(21177..22385)
                     /gene="hydF"
                     /locus_tag="ACGI3L_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HFG9198303.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTQKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(22400..22651)
                     /locus_tag="ACGI3L_002606"
     CDS             complement(22400..22651)
                     /locus_tag="ACGI3L_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0065007 - biological regulation [Evidence
                     IEA];
                     GO_process: GO:0065009 - regulation of molecular function
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TM1266 family iron-only hydrogenase system
                     putative regulator"
                     /protein_id="HFG9198304.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
BASE COUNT         8676 a         2642 c         3739 g         7718 t
ORIGIN      
        1 tataaagtat gatatttgaa taaaaagaat gtataataag tataataatt tgtatttatt
       61 attgggaaag gaaaatgtta atatggatag ttataaacaa cttaaagcta aaataccctg
      121 taaggaaaca ggtatagaaa taaagaggac tttatgtgat atttgttcgc caggagtaca
      181 ttgtggaatt gatgcatatg ttaaagatgg taaagtaata aaaatagaag gtacaaaaga
      241 acatccaatg aataaagggt tgttatgtac caaaggtctt tgcaatagag aatatatcta
      301 tagagaagat agaataaaaa cacctctaaa aagaattgga aaaagaggtg aaggaaaatt
      361 taaaccaata tcatgggatg aagcttatag agaaatagca gaaaaattaa atagagtaaa
      421 atctgagtat ggagcaaagc atgtagcttt ttttacgggt tatggaaagt ggtatagacc
      481 ttttttacaa aggtttgcat cttcatttgg ttcacctaat tatggtacag aatctagttc
      541 atgttcaaca tcagcacaga tggctggaaa tgttgctact ggaagaaact ttacaatgca
      601 agatatggag aatgcaaaaa cttatttagg gtggggattt aatccatact actctaaatt
      661 tttaaatagt gtgaatctaa taaaattaaa agaaaaaggt ctaaaattta taattgtaga
      721 ccctagaata acaccgacaa ctcaaaaact agcagattta catttaagaa ttaaacctgg
      781 aactgatgga gctttagctc ttggaatggc gaatctattt atacaaaagg atttaataga
      841 tagagaatac atagaaaagc atgtacatgg atttaatgaa tataaagaat atgtaaaatt
      901 atttgattta gatactgtaa gtagaattac aggagtttct aaagataata tagtaaaagc
      961 tgttgagatg ttgtcacaag gtccattttg tataaatgaa agtgcagctc caatagttca
     1021 tcatcaaaat ggatttcaaa attatagagc aatgatgtct ttatccgcta taacaggtaa
     1081 ttatgataga ataggtggaa acataccaaa acaagattac tttgctggta agataggtgg
     1141 attccaaaca ctagaaaaag agtttgtaaa agaagttcta cctaaaaata taaatgaaag
     1201 aattggtgga gaaagatttc ctctatggaa tgaaatggtg actcaatttc aagctatgga
     1261 tttacctagg caaatagaag aaaagacacc atatgaaata agagctttgt tttgtcatgg
     1321 gataaatgct agaatgtttc ctaattcagg gagacttttt aaagcgttga atagtgtaga
     1381 tttttttgtg aatatagatt tatttatgac agatacatca aaatatgcag atatactttt
     1441 acctgcatgt acatcatttg agagagaaga atgtaagagt tatccaggag ggtatattac
     1501 atataccaaa aaagttattg ataaattata cgattcaaaa tcagatgtag aaatactttc
     1561 agatttagca aatgctatga atatagatga tgatttatta aaagcaggtt atgaagcaag
     1621 tgtaagacat atgtttaaaa atacatgtgt agatgtagat aaacttaaag aaagtgattt
     1681 accattaaaa tgtaaagatt ttaagccata tatagtaggt tcatatacaa gagaagggta
     1741 tgatactagc acttctaggt ttgaattaaa atctacaatt attgaaaaat ataaagattt
     1801 tgggctggat gcactaccaa catatagagg atttaatgat aatatagatg atgaatatac
     1861 tcatttattg acatcaggag caagaatttc aaatgcacta cattcaagac ttcatgacat
     1921 caaactttca agaatattaa aaaatgaagc taattgtgat atttctagct tagatgcaaa
     1981 agaattgggt gttatcagtg gagattatat aaaaataact actaagatag gaagtttgga
     2041 tgtaaaagtc aatgttactg atagagtctt atataagaat atacatatgt atcatggata
     2101 tagagaagct gatataaata gtattatttg tgataatttt gacccttata gtggattccc
     2161 tgcgtataga agttgtaagt gtaagattga aaaaatgaat agataaatgg agagatataa
     2221 tgaaaagttt atttaaattt aataaagaat tatgtacagc atgtggagca tgtttgcttg
     2281 catgtataga ccaaaatgat aataatatag acaatggtga actttttaga catgtattta
     2341 caatagagga aggtgaaaat atagaatatt tttcattagc atgtatacat tgtaatgagc
     2401 caaaatgttt aggtgtatgt cctaaaaatt gttttaaaaa agaagaagga ttcattgtat
     2461 tagacaatca aaactgtata gggtgtaaac tttgtgaaaa agcttgtgaa tatggagcct
     2521 taatttatgg aaatgatggt aaggcaaata agtgtaatgg ttgtattgag agatataagt
     2581 gtggtatgga ttcaccttgt gtaatggtat gccctacagg agcattaaaa tttaataaat
     2641 aattgtatta aattgctata ctacttttaa ataattgtgt taagaattat tttttgatat
     2701 acttttgtaa tataaaatgt aaataaaaca aatacaaagt atataaaata tatttttaga
     2761 ataaagtgtg ctttagatta aatttagaaa aataaattag acaggagaac ttaatatggt
     2821 aaaagtatta gcctttatgg gcagtccaag aaaaaaaggg aatgtagaca caatacttga
     2881 tgagataata aaaggtgtaa atgataataa tgttgaagtt aaaaaatatt atctaaatga
     2941 tatgaatatt aaaggatgtc aaggctgtct atactgtaga aaagttccta cttgtgcatt
     3001 taaagacgat atgattgaca tatatgaaga tataaaaagt gctgaatata taataattgg
     3061 ttcgccagta tatatatgtc aggtatcagc tcaaacaaag ctacttttag atagattgta
     3121 tcctttaaca gagataaata agtctaaaca tatacctagg tttggtcaaa aaaagttaat
     3181 catggtctat actcaagcag ctcctatttc gtttttattt aaaaaatatt ttaagtatac
     3241 tgcaaaacat ttaaagggca tgggattaaa tcactacaaa actatagttg taaccaaagc
     3301 atttgaaaga aattccacta aaaaaaattt taaggtattg aaaaaagcct ataaacttgg
     3361 aatgaaaata gccattgata tcaatggata gataaaagtt taatttatag tatagctaaa
     3421 ggagcattaa ttattaatac tccttttttg tataaaggtt tctagaaaat aactaataaa
     3481 aaacaatatt atttgaatac agatattata caagcctaga tatctaactt gttttgaaaa
     3541 taaaagattt caaatttatt tttgttaaaa gataacaagc cttcatctcg catcttgcca
     3601 agctctcttg acatagaact tctgtcaaca cataaaaaat cagccatttc atttcttgaa
     3661 aagggaattg taaactggtg gctacctgtt tgttctatct gttttgaaaa atacataagc
     3721 aatttctcgc gagttgtttt acgagaaagt aattctattt tattgtgaag taaaatgttt
     3781 ttttcagcta ttaattgtag catattttca acaagcctat tatgaaatac acatgcagat
     3841 gaacaaatac cagttacact tttaaacttt ataaataaaa cttcgcaaga agatgttgtg
     3901 gttactgtaa cattactttt atgtagtcta gtacatgcga atacctctcc aaataaatct
     3961 ccaggcaaga gttcagctac aatattccta ttcccttcga tatcttcctt tattatatga
     4021 gcacttcctt taagcataat tccaatagaa gtaacttcac ttccaacaga gaatattata
     4081 ctatcttttg ggtaagtctt atctacaaca cctaaacatt ccaacatttc ttcaagttca
     4141 tcacttttaa ttccttcaaa tagaggaatt tttttaagta agtctatatg cttttctaaa
     4201 aattttttca aataatcact tccttgttgc atatgcaacc gataatttgt tttcattgta
     4261 ctatactaag tttataaaag caaggggata taaaaatcct actacaagaa atttgaaata
     4321 aagaaatata ggtattaaaa ataaatatat aagaaatcaa tactttaaat taaaaaaatt
     4381 ttatgaggtg atataaatga tgagaaaaat aattaaaatt gatgaggaaa agtgtaatgg
     4441 ttgtggacta tgtgttgaag cttgtcatga agaagctata ggaatggtaa atggaaaagc
     4501 aaaactttta agagatgact attgtgatgg gctgggagat tgtctgccaa cttgtccaac
     4561 aaatgcgatt tcatttgagt atagagaagc agcagaatat gatgaagctg cagtaaaagc
     4621 aaatatggaa gcaaagaaag cacaaaagaa aactttagca tgtggatgtc caggttctca
     4681 gtctaagtca ataaatagag aggtttcaaa tagtacgtct ataagcaatg atatagtaga
     4741 gataaaaggt tctcaactta atcaatggcc agtacaaata aaattagtac caactaatgc
     4801 atcatattta aagaatgcaa gttttttaat agcagcagac tgtacagcgt atgcatatgg
     4861 aaattttcat aataaattta tgaaaaataa ggttacatta atcggatgcc ctaaacttga
     4921 tgaagttgac tatgctgaaa aacttacaga gattttaaaa gaaaatgata ttaaaaatat
     4981 agtagtaaca cgtatggaag ttccttgctg tggtggtata gtaaatgctg ttaagacagc
     5041 tctacaaaat agtggaaaaa tgataccatg gcaaatagtt actatatctg tagatggaaa
     5101 aattgtagat ggagaaattt aattaagtga attatagaaa aatataataa attttaataa
     5161 ataaaaaggg aggaataaaa aatggaaaaa atgttttgtt ttcaatgtga acaaacagca
     5221 ggaggtaaag gttgtactat aaatggtgtc tgtggtaaaa aggggggtac agctaactta
     5281 caagacgaac ttacaggagt gttgattggt ctttcaagag caactattgg aaataagaat
     5341 agaccaacaa gtgaaacaga taaaattatg atagaggggc tattcactac tataacgaat
     5401 gtaagttttg atgatgaagc tataaaaaga caaattgaaa aaactgaggt agaaaaaagt
     5461 aaacttgtac ctagatgttc agattgttca acaacttgta atagaaatga taactatgat
     5521 atgaaggatt tatggaatga taatgaggac atacgttcat taaaatcatt aatcttattt
     5581 ggattaagag gtatggctgc ctatgcatat catgcaatgg tacttggtta tacagacaaa
     5641 gacgtaaatg aatttttcta tgaaggatta atagcagttg gaggagactt gtctattgac
     5701 gaacttttag gtctagttat gaaaactgga gaaataaact taaaatgtat ggaattgctt
     5761 gatagagcaa atactgaaac ttatggaaca ccagaaccga ctcaggtatc tatgaaaatc
     5821 gagaaagggc catttattgt agttacagga catgaccttt atgatttaca caaattatta
     5881 gaacaaacga aagataaggg tataaatata tatactcatg gtgagttatt accagcacat
     5941 gcatatccaa aactaaaaga atataaacat ctaaaaggta attttggtac agcatggcaa
     6001 aaccagcaaa aagaatttga taatattcct gctccaatat tatttacaac aaactgttta
     6061 atgcctgtta aagatagtta tagagataga gtatttacta cagaagtagt tgcttatcca
     6121 ggtatggttc atattgatga agataaagat ttttctagtg taatagaaaa agctcttgaa
     6181 cttggaggat atagagaaga tgttcatatg actggtatta atggaggaga tacattaact
     6241 actggttttg caagaggtac agtttcatct gtacaagata aagtagtaga tgctgtaaag
     6301 agtggagcta taagacactt tttattggtt ggaggttgtg atggtgcaaa acctggaaga
     6361 aattattaca ctgaatttgt aaaacaagct cctaaagaca ctgttatatt gacacttgca
     6421 tgtggaaaat atagatttaa tgatttagac cttggggata taggtggctt acctcgttta
     6481 atggatatgg gacaatgtaa tgatgcttat agtgcaatta aagtggcagt ttcattggca
     6541 aatgcttttg aatgtggagt aaatgatttg cctcttagca tggtactgtc atggtatgag
     6601 cagaaagctg tttgtatact tcttacacta cttcatttag gtatcaaaaa tatctatata
     6661 gggccttctt tgccagcatt cttatctaag aatgtattag atatattggt tgataaattt
     6721 gcattgacac ctatatctac tcctgaagaa gatatgaaga agattttagg ataaataaac
     6781 atatctatac ttaaagatat ttatagttaa aatattttta agtatgccac aattaagata
     6841 aggggttaaa cttaaaattt gattaaaaaa tcaattttga gatgaccctt tatttatttt
     6901 ttgtaataat tgaaaaataa acctgctttc agtatattct ttttaagaat ctttgtatta
     6961 aatttataat acttagatat ataatatctt atatatttta ttttaagtat taaaggtttg
     7021 aatgtaactt aaatattaaa agaggaacat tgtaatatgt aacttgcata aaatatatat
     7081 actatagtga aattattttg attaaaattt aaaatataag gtgttttatg tgggggtata
     7141 tgtatatgaa aaattctaat tttaatatat tggcatttga tggtggtgga ttaaaagggg
     7201 cattgagtat atccatactt gagaggatag taaaagagta tccaaatcta ttaaacaata
     7261 taaatatgtt tggaggtaca tctacaggga gtctaattgc actagggctt gcgtatggtg
     7321 taagccctaa agagataaaa gaactttact caattgaaaa ttcaaagtat atttttaata
     7381 aaagttatgc agaaatactc agaccaaagt atgaaaacaa aaacttaaaa gaagttttat
     7441 taagtatatt tccagaggaa ctagaattaa aagatttaaa taaattagta atgataccaa
     7501 gtttttatat aggaaatgag gaaaatgcat ggaaaccagt gttttataac aatatgccaa
     7561 attcttttac aaagactagc aaagttgtag atgtagcaat ggcaagtagt gctgctccgg
     7621 tattttttcc aacatataat cgtcatgttg atggaggaat aatagcaact gacccgagtt
     7681 tagcgtgtat aattcatgcc attgacagtg gatttaaact taagaataca agactttttt
     7741 caatagggac tggatatgta tataacagta taaaggcaga tactaccgaa tggggagcta
     7801 ttgactggat aattaataaa gaacccgatt taccaattat atctattacc ttagaaggaa
     7861 attctcaaat gagtcagtta ttttctcaaa aacttcttgg agataattac tatagattaa
     7921 atcctaagat ggaaaaagat gtagctatgg atgattgtga tgcattagaa tatctaatgt
     7981 ctttaggaga aaattgtgat ataaaagatg cttttggatg gataaagaaa aagagctttt
     8041 atagaaatta gattcaattt gcaattgtat ttttacacat gatttcattg agtaggtaaa
     8101 aataataaaa tgcagattat taagttactt cttagggaat aaataaagta taatttattt
     8161 aaggagtgat gaaaatgata aaacttgcta ctttttcagg tggatgtttt tggtgtatgg
     8221 taaaaccttt tgataagtat gatggagtta ttaaagtagt ttctggatat acaggtggtc
     8281 atgttgaaaa ccctacatat caagaggtat gctcaggaac tactggtcat ttagaagcaa
     8341 ttcaaataac atatgatgat gatataataa gttatgatga acttctaaat atcttctgga
     8401 aacagattaa tcctacagat gatggtggac aatttggtga taggggaact caatataaga
     8461 ctgctatatt ttatcatgat gaagaacaaa aaaatatagc tttagagtca agagaacatc
     8521 tggaaaatag taaaatattt gatagtaaaa tagtgactga tataattcca gcaactaaat
     8581 tctacgaagc agaagaaaat catcaggatt attataagaa aagaccatta aactacaata
     8641 tgtattataa agggtctgga agatataatt ttgtaaaaag ccattgggat ggaaacaata
     8701 taaataggga agagttaaaa aagactctaa ctcctataca atttgaagtc actcaaaatg
     8761 atatgacaga agtacctttt gaaaatgaat attatgacaa taacaaagag ggaatttatg
     8821 ttgatattgt aagtggagaa gtgttatttt cttcaaaaga taaatttgat tctggatgtg
     8881 ggtggccaag tttttcaaag ccagttatag ataaatctat cattgagaga agtgatttct
     8941 cacaaggtat gtacagagtt gaagtaagaa gtgctaaagg aaattctcat ttaggtcatg
     9001 tatttgatga tggtccaaaa gaacttggag gtttaagata ttgtataaat tctgcttctc
     9061 ttaaatttat accaagagaa aatatggaag ctttaggata tggagaatat ttaaaacttt
     9121 ttgagtaatt aggaatattt attataaact tatctaaaag gtgaaaatat aaaaaaatat
     9181 tttcaccttt tgtttttttg tcaataatat gataaattat taattgtaat cttatttata
     9241 ccaatagatt aagaatttaa ttttgaaaga gagaaaacaa atgaatttaa aagactttaa
     9301 tggaaagaga ttaaaatcag ctagaatttt tagagcaaag acgatagaac agttgtctaa
     9361 agaaactaaa ataaataaaa aagatttaaa agcttttgag gaaaataagt atgtaccaaa
     9421 tatagaaaat acattaaaat tatctaatat attaaatttt ccaaaagagt atttttataa
     9481 aaatgaaaat ataaatatcg ttgtagagga tagccacttt aaccctcaat ctaaactacc
     9541 tagagtagaa gagatttctt atagagaaaa aataattata atacataaaa tatattcatt
     9601 tatggagaat tatattaagt ttccaaaaga aaacttgcca aatagaaaag taatgtcaga
     9661 tattaatata aatgatatag aatctcttgc atataagact agagagtttt gggatttaaa
     9721 tagtactcca atagtaaata tggtaagttt gttagagtct aaagggatta taatatcagg
     9781 tatgaatgta gatagaaaag gggcaactat ctttactcaa aaacagagaa ttagtaaaga
     9841 atctaaatat ctaatatctc tgggtaatga caaaaagtca gcatcaatta gaaattatac
     9901 tttggcatgt gagcttggat atataatatc aagtgaatta agaataccaa gtaagcaatt
     9961 ttcagaagat gagtatgcct gtgcattttt attgccaaaa gagagttttt taaaagattt
    10021 gactcatcca gaagatttag attattatgt agaactaaag aaaaaatgga ttgtacctat
    10081 atctgctatg atttttagag catataatct agaaaagata aattacaaaa aatacaatta
    10141 tcttatgaat gaaatggata aaaaaggctg gttgatagaa gaaccactag acaaaatgaa
    10201 aggttcaagc ccaacgtatt taaaaagagc agttgaatta ttgatagaaa ataaaataat
    10261 gagtgtaaat agtatagtat caagtttaga ggaatttgga ataaatcttt atccagaaga
    10321 cttagaatta ttgatgggat tgaaaaaagg attgttatct caagaggtaa ataaaaaaag
    10381 taaagttata aaatttgatg gtaaaaaata ggtttatatt ttagtattaa aattaaaagc
    10441 aggtacaaat gatttaaaca ttaacttagt taaaggtctt ttcaataagt catttacctg
    10501 cttttagtgt aagaaagaat attgaatcta aagtgttttt gaaagtgcaa tatattccct
    10561 taaaacagaa caagatttat taaattcatt ttgctcatat tcagtcatat tgatttcaat
    10621 aatttcttca ataccatctt ttcctataac acatggaaca cctgcaaata catttctttc
    10681 gttatattga ccttctagta atgtagaaac tggaagaact tttttctcat tgtgtagtat
    10741 agcttttaca atttctacta aagcagtacc tataccaaat tctgtacaat ctttaccatt
    10801 tattatactt atccctgttt ttttattttt ttcaactatt gatggtaagt ctaaattgct
    10861 ataagtactt gggttgtctt ttatcatgtc taagattggt ttaccaccaa ttgaaacatg
    10921 agaccaagga accatttgag aatctccatg ttcacccata gaataagctt gaattgattg
    10981 ttgagcgatt ccagtttctt cagataaaat ccttctaagt cttgttgaat ctaaagctgt
    11041 tccagttcca atgactttgt ttttaggaaa gccagatttt tcccaaatat aatttgtaac
    11101 tacatcaaca ggattagata tgactacaaa tataccatca aagccagaat caactatggg
    11161 ttttactata gattttatca ttccaatagt tggtcttagt aaatctaatc tagttgtgtt
    11221 ttgtctacgt aaaggccctt ctgaagagtc tgcaacactt atcactacta tgtcagaatc
    11281 tttacagtca gaaaaagttc ctttttctat atgtacttta tgtggcagat atgaaactgc
    11341 atcagctaaa tctaaagctt gagcttttga tttagattca tctatatcaa tcataaagag
    11401 ttcatcacaa actccttgag ttattaaact aaatccacaa tgagaaccaa catgccctga
    11461 acctacaata gatatttttc ttggctttat tgccatttta aatcactccc cctaaaataa
    11521 cgatacattg aaaattatag atgttattaa aagctgtttt tggatatttt aatattctat
    11581 tatttcagaa aatttattta atatgatttt atactaaaat ttttaaaaaa gcaatgttaa
    11641 tatactctct attagtgaat attaaagtat tatatgtata ttaataatta ttaaaatatg
    11701 taatgtcact gatagttaga atatttaagt gctaaaagat gtgtataaat aataatgatg
    11761 tcagtttata atgatattaa attgagatat actgtttctc taaattaaaa aataaaggag
    11821 taaatgtgtt atgaattatc atacaaaaga agaattggtg gaagcactga gagtagtatc
    11881 ttcaagtatt attaattgtg gaaaaggaca gaagaaattt tctgaggaga catctcatca
    11941 tacacgtttt aagaatatta tagaagtaat gtatatttca aaatcattaa taatggatga
    12001 aattagtaaa agagattgaa gcttattttg caatttaaca tgttttaata tacattttat
    12061 tatataagaa aataagtaaa catacatgtt ataaaatatt gaaataatat acaattataa
    12121 atttgttaac attaatatct atatgttaaa atatagtaga agatgttagt aaataatagg
    12181 atgagttcta ttttaataca attaaattaa gcttagtttg aaatttgtat ctaaaaagta
    12241 aagtaatcta gaattaagaa aatggagata gaattataat ggaaaaatta tattatacaa
    12301 atcagtatat aagagatttt acagcagaaa taattgaaat aaaagaagta gaaaataagt
    12361 atcatgtttt attagataag acagcttttt ttcctggtgg aggaggtcag tttggagacc
    12421 tgggaaaaat agagaatgat gatgtaataa atgtgtatga agatggaaaa aaaatatacc
    12481 atgtattaga taaaaaacct ataaagatac ataaggtaaa gtgtagtatt gattgggata
    12541 gaagagaaga tggaatgcat caacattttg gacaacatgt attgtctgga tgttttttta
    12601 aaacttttaa tgcaaatacg acaggttttc atttgggaaa tgagtatagt acagtagata
    12661 tagaaggtaa tttagaagag gataaaatta gagagataga gttgtttgcc aatgaaatta
    12721 ttcgtcaaaa tatacaagta gagacattac ttccaacgaa aaaagaacta aaaaagattt
    12781 ggttaagacg tgatttgcca aatactgatg aagagataag agtaataaaa ataggtgatt
    12841 tagatacgaa tgcatgttgt ggagtgcatc caaaatcaac tggtgaattg agaatgataa
    12901 aaataaagaa atgggaaaaa cataagtcaa gtacaagaat agagtttcta gcaggtaaaa
    12961 gggcagtgga tgaagtattg aagagggata tatatttgac taaaatatgt agatatttaa
    13021 gctgtagtga ggaagatgct ataaatggta ttgtaaatct aaatagtaaa gtggaagagg
    13081 ctttaattaa aaaaagaagg cttgaagaag tagtatctac atatcaggtc aaagaaatga
    13141 ttgaaaaagc aaataaggtt ggcaatattt cggtcattaa aaaaatttat gatgatgaag
    13201 atttgaaata tgtaaataag atagcaaata aaattgcaga atatgaaaat agtattgcat
    13261 tattagctgt taaatttaat gataaaataa atttagtttt tgcatgttct aaaaatttaa
    13321 aagatattaa tatgggagtt ttattaaagg atgcaataaa tcttatagat ggcaagggtg
    13381 gtggaagtaa agtattagct caaggaggag gtaagaataa tggaaattta gaggctacac
    13441 ttgattatgc atttatgaag atagaaaaaa ctctataaat atattatata aaaaacctta
    13501 gtagataaaa tagatatgga ggaataagta tggagcaaca aaaggactac atagagttat
    13561 atgaaaatga agaactaata gagataagag aagcacgtat ggatgatttg gatacaatag
    13621 caaaatttaa ttataatttg gctaaagaaa ctgaaggaaa agaacttgat atggatgttt
    13681 taactaaagg tgtaaaagca ttgttattag atgagagaaa aggaaaatat catgtatata
    13741 cagtatttga taaagttgtt gcacagatta tgtatacata tgagtggagt gattggagaa
    13801 atggaaattt cctttggatt cagagtgtat atgtagataa ggaatataga agaaaaggta
    13861 tctttaatta tttatttaat tatataaaaa atatatgtga taaagatgaa aatatagttg
    13921 gaatgagatt atatgtagaa aaagaaaaca taaatgcaaa agcaacatat gagtctttaa
    13981 atatgtatga gtgtgattat aatatgtatg aatacgaagt agtacattcg taatataaat
    14041 ttgtaatact gttatactga tgttataaag tattgattat attgacgatt atatgaaata
    14101 aactggatat tataattaga atttttaggg ggtataaaaa tgggcgtttt aaaaggaatg
    14161 ttttatgtat ttttattttt agatttagtg tcaatattct gtttcttttt caataaagga
    14221 aaaatagcat ctaataaaat tgtgtttaat gcaataggag tacttacatt tgtactttgt
    14281 tttatgcttt ttagttatta tcctaataat aatcttattg gaaaatttat tgcttctcta
    14341 ttttttatat ttggagttgc aggagttatg ttgaaagaaa aaaatttttt atatgctaga
    14401 cttcttttaa ctgtagttat agttttttct acattaagat tgttcgttat tcaataaaat
    14461 gtatttgtat aaaaatttat taaagtctac acatttaagt gtaggctttt ttgatttttt
    14521 gtttgaaaat taaggaaatt ttaaggaaat tttaaaatcg tcttaaatat ttattgatat
    14581 acttaaaata ttaatagcga aaggagactt atcagtgata gaaagtaaaa agtcagaaaa
    14641 attgttactg tcaattatat acataatatt tttggtatat attttaatga ttataagaat
    14701 aattttattt agagatgtac caatttacgc tattttcaag ggaacgttta ggaatgtaaa
    14761 tttaattcca ttttatacaa tatatcaatt tatagtagat agtaatcttg actttatgaa
    14821 agctactgta aatattatag aaaatatagg tatatttatt cctatgggaa tttttttacc
    14881 tatagtatgt aaaaatctaa ataaaaaaac tataattata gtaattatac ttgttagcct
    14941 agcatttgaa ttaacacaat atatttttgc tcttggaagt agtgatatag atgatgttat
    15001 tttaaattca ttaggtggca taattggaat taatatttac ataaacatga ataaattatt
    15061 tcccaatgat attaacagat ttaaggctat aataggtact agtttagttt taggagttat
    15121 aggattagga gttatttcta aaaattatca taacttacta acttttaaat ttagacctga
    15181 tagaaaaata tcaaaaatat taattgaaga aaatagggaa ataattaaag atataaataa
    15241 agatacagta gatatagttg ggacatttga gagctttaaa aaaggaataa taactattaa
    15301 agcaggttct aataacaaag taaagagacc agagaattta attgattctg atggaaatat
    15361 aagaatttat ttaaatgaaa atacaaaatt agtatcttat ataattacca aagaatcaaa
    15421 aatggatata gttaaatatg aggaatttga tgtgaagaat ttagatttat taaggagata
    15481 tgatactatt aatgtttgga ttgataaaga aaatcagcca aaggataaac atggtattat
    15541 ggctagtaaa ttattaattg gattgtatga ataaaatatt aaacaagaat aaaagaataa
    15601 caaatataaa aaacgaaaaa actatttcta taattatttt tacgttgtgc ataaaataag
    15661 aacattagtg aaggagtaga gataaattat ggagataata aaatatatct tgtacttttt
    15721 tatatattca tttttaggat ggacagtaga aagtatagga tgttctatag caagcaaaag
    15781 aataatcaac agaggttttt taaatggtcc aatatgtcct gtttatggtt ttggagcggt
    15841 aattgtgata tcactattgg gaagatttaa taatgtagta atagtatttc tattaggaat
    15901 gattttaact acgatactag aatattttac aggatttatt ttagaaacct tatttcatgc
    15961 taaatggtgg gattattctg acagaaaatt caatataaag ggtagagtat gtttaaaaaa
    16021 tgcaatatac tttggtgtaa tgtctgtttt aataataaga tttatacatc catttataaa
    16081 atattttgta agtataattc catatagaat attaatttca atggctataa ttacaacact
    16141 ttggactata cttgatttga ttgttactat tataacactt aaaaaattag atataaagtt
    16201 aaacttacta gacgatataa ttacagacct taatgatata aatgtgaaat tggataaatt
    16261 tgatagagga gaaatacaag ctttatttaa aacaataaat aacgacgaat tagaagttag
    16321 agaaaaaata aacaaaataa atagtaagtt ggaccgtata gagtctaata ttattttaca
    16381 aaaaagagtt ataaaagctt ttccacatat aaaacataaa aaacaacaag agcaactaga
    16441 acattttaaa aaaattatta atgagaaaag gtaattatac aatttaatga agacgaatag
    16501 aataatggta tttataagat gattttcaga ggactctata aaaatagaat agagtccttt
    16561 attttttgaa aaataatgtt tatttgataa aaataaaata tattgtttct gaataacaaa
    16621 tattttgaaa attataaaaa catatattga caatttgtgt caaaaatact aacattaagt
    16681 atataaagaa ttttatatga gaatatcttt ataaatcgca ataattttaa aacataaatt
    16741 tatttaaaga ggggatgatt tgccaatgag cgagataact agtcaaatga taagtacaga
    16801 agaaaaaaaa tatgttgcta aaactcaaaa gataccttat tatccagtag catttaaatc
    16861 aggtgatggt gcaatgctat atgattatga aggtaatgaa tatgtagatt ttttagcaag
    16921 tgcaggctct gcaaatgtag gtcatggtaa taaggaaatc tcacaagcag ttaaagaaca
    16981 aatggatgat ataacacaat atacacttgc atatttccat agtgatcctc ctgtaaaatt
    17041 agctgagaag cttgtggaaa tagcccctgg agataatgat aaaaaagtac tatacagtgc
    17101 aactggttct gcttgtatag atgctgctat aaaattagca agaggatata ctggaagaac
    17161 aaagataata tctatgtgtg aatcttatca tggaagtact tatggagcta tatctatatc
    17221 tgctttaagt acaaatatga gaagaaaaat gggtccattg ttaccagaag tttatcactt
    17281 ccattatcct gataaaaata gaacagctaa agaatgttta gatgagatag aatatgcttt
    17341 tgcacactat ctaccagcag aagaggtagc tgcaatattt atagagccaa ttgcaggaga
    17401 tgcaggaata atagtgcctc cagtagagtg ggtacaaggt ttaagtaaaa tatgtaaaga
    17461 aaatggaata ttacttgtaa gtgatgaaat acaacaaggt atgggaagaa caggtaagtg
    17521 gtttggtata gaaaattttg gtgttgaagc agaccttata gttcttggaa aatctgttgg
    17581 aggtggatta cctctaggag cagttgttgg aagaacagaa ataatgcaaa gtcttgatgc
    17641 accagcacat ttatttactt tagctggaaa cacaacagta tgtgtggctg ctttaaaatc
    17701 tatagagata attgaaaaag aaaacttact tcaaaagagt atagaaatgg gagattatat
    17761 taaagcagga tttgaaaaac taaaagaaaa atacgatata attggagaaa taagaggcat
    17821 aggattatct ataggagttg atatagttaa aggaaaaggt tctaatgaaa aacatccaga
    17881 tgctacagct aagatatgtt atagatgtat acaaactgga ttaataatga tattcttagg
    17941 acaatctact ttaagagtgc aaccacctct agtaataact aaggagcaag tagataaagc
    18001 aatgaacatc atagattctg caatagatga ttatttaaat ggtagaattg gtgatgaagt
    18061 atatgaagta actcaaggtt ggtaaaataa atattaaatg aaaataggag ttatctcaat
    18121 tttagaaaat tatttctgaa atgagataac tcttttaagt tacccacaaa taagaaaatt
    18181 gtttgattca ttaaagacta tatttcggat gtcgtttttg tgagtatcag agacagtatt
    18241 acgagaataa ttacctttat tcgtactatc tgttaattta gttataatta agatagctaa
    18301 aagaataaga attactgtgt ataaagcaat aacatatggt tttcttttat atttgtattt
    18361 gttattgaaa aaagaatggc cataattatt tttatttact ttagatgtat ttgtattctt
    18421 tttcttgtta cctttctttt tatcatcctt ttttctattt ttagggtaag gaatgacttt
    18481 gtgtgtatta tcaagtttga tatttttatt tttttgaata ttgttttcca ggctagcctt
    18541 tttttctcca aattgaatag ttttattggt attgttgtta tctttcaatg ttaatctccc
    18601 tcccttaaac tttcccttta gataatatta ctactaacct atggaatata caataaataa
    18661 tatataagta ataaaatttt ataggtataa atctctttct ccacgctcta aggcagtcat
    18721 attgttagat actatgtttc ttatatcttc tctttctatc ttacctattt cttctgcgat
    18781 aagtttttta cccataattt taagttcttc atctccataa tcgattaaaa attcatttaa
    18841 tgtagtaaga gcatttggtg tacatacatt atggatttgt cgacttttag ctaagctcat
    18901 gaatctatcg ccagttctac ctttacgata acaagctgta caataactag gtatatatcc
    18961 atcagtaatc agttctttaa gcacctcaac agggcttcta tggtctccaa cttcaaattg
    19021 ttctgtattg tcaccatctt catatgcttt atatcctcca acacctgtta gagaacctgc
    19081 actaatttgt gatacaccat attttagtaa ctcatttctc atttcagcag tttctctagt
    19141 ggacattatg attccagtaa aaggaacagc caatctagtt atagctacta tttttttgaa
    19201 catatcgtca gaaactaagt gaggaaaatc ttctaagctc ataccttcag cttttttcaa
    19261 tctagggaaa gatatagtat ggaaacctac accaaatttt tcctctaagt gttcgttgtg
    19321 catcataagt cctagaactt caaatttagg gtcagataaa ccaaataaaa ctcctgcacc
    19381 aacatcatca acaccagctt ccatagctct atcaaaagct gttaaatggt aataatagtc
    19441 attttttata gattgaccat gcatttttat aaatgttggt ttgtgataag tttcttggaa
    19501 taatatataa gttcctattc ctttttcttt tagtaattta tactcatcta cacttgtagc
    19561 tgctatgtta acgtttaccc ttcttatatt tccgttttca ttatatgttg aataaattgc
    19621 atctaagcaa tctaagatgt aatttatatc acaattttta gggtcttcac cagcttctag
    19681 agcaagtctt ttatgaccca ttttttctaa tattttaacc tcttccttta tctcttccat
    19741 ggtaagtttt tttcttttaa atttgttgca tttactaaaa ccgcaataaa cacattcatt
    19801 tacacagtag tttgatacat aaagaggggc aaataaaacc actctattac catatatttc
    19861 attttttatt tgcccagcta tactaaataa tctatctagt tgttttttat cttctacttc
    19921 aagaagtgta gctatatctt tataactaag tttttccctt ctatcagcct tatcaagtac
    19981 cttttcaata tcatcagaag ttgaattttt tgcatcttct aataaagaat taataagttc
    20041 atggtttatg aacatttaca aacgcctcca ttcaatatta tcaccgcgag aatagtcaac
    20101 ttcaagtcct aatgacttga tgttttcttc taaactttgg tgatattcac aagcttcttg
    20161 accagtaaag gctttgttat cgtaaagaga atattgtttt ctaaattctt gaggagaaag
    20221 gtttggcata attacattgc aaccagctaa aagacctgca tttctaccac tagggtttat
    20281 agatgccaag gctgttgtag cgggtaataa aacttttgga agtagaagtc ttgtaattga
    20341 aagcataagt aatgtcttct ctaaatctcc atgtttataa tccttaaaaa ttgtatcatg
    20401 gtgtggaata aaaggtccta ttccaaccat atgaggattt aactctttta ggtataataa
    20461 atcacgaaca aggtcttcgt tgttctgaaa tggtgattca accataaatc cagcacctac
    20521 ctgataacca atttctttaa ggttttttag gcattctttt ctagttctaa gctcaatgtt
    20581 tggcggatgt aattttttat aatgactgtc tgtagcagtt tcatgtctta aaagatatct
    20641 atctgcacca cataaaaagt attttttata cgaatcataa ctcttttctc ctagtgatag
    20701 agttatggca caatcctcat atttattttt tatacttgaa acaatttcac atattttatc
    20761 atcagtaaaa tatgcatctt caccaccttg caaaacgaat gttctgtatc ctattttata
    20821 acctatatca caacattcaa gtatttcatc aagtgaaagc ctgtatctta tgatattttt
    20881 attagaagat tgtattccac aatagtagca attattttta caatagtttg taagctctat
    20941 aagtcctctc aagtagactc tatttccata atgtttattt ctcatgtcgc tagcttgttt
    21001 ataaagatag tttcttaaat tttgttcgaa gttatattcc tcattgtcga tattttctat
    21061 taaatatagt agttcatcaa aacttaatga attaatgctg taaagtttat ctataaagta
    21121 tttaatctta tttttagtca tattcaaata tgtaattatt aagtatagtt aaatttttaa
    21181 taattgaaaa gttcaagtga tctttccaaa atacctttta catatgctat taagacacca
    21241 tagtttacaa taggtacatt gaaagatttt gccttttcta ttctagataa cattccagct
    21301 ctattcatca tacaagctcc acagtgaact acaagggcat atttatttat atcttcagtg
    21361 aaggatactc cagaactaaa ttcaaaagta atgtttttgc cagttttctt tctaatcata
    21421 ttaggaattt ttactgttcc aatatcatca gtttgtctat gatgggtaca tccttcggcc
    21481 atcaagattt tatcaccatc ttttaaattt tctaaagcat aagctccatt aatcaattct
    21541 ttaaggtctc ccttttgtct agcaaacaat atagaaaaag atgtaagagg aatatctttt
    21601 tgtgtatctt tatctacttg tggaaatact tgagagtcag taataacaag ttttggtttt
    21661 ttgcctaaat tagatagagt ttcttttaaa ctatcttctt ttgtaactat agaaattgca
    21721 ccattatcca aaatatctct tataacttgc tgttgaggaa gtataagtct accttttgga
    21781 gctgctttat ctattggaac aactaaaaca actaaatcat ttggttcaat taaatctgat
    21841 accaatttga actcagtgct atccttaggc aaaactttta ttatttcatt ttttaaattt
    21901 tcaattccaa ttttatctgt tgatgagaca gaaacaactg gacatttaac tttattttta
    21961 gttaagttta aaatttctga ttgattctta atagtatcaa ttttgttaag aattagaata
    22021 tgagggatat tcttatcatt aaatttttca attagtgaca aatcttcttg tgatatacca
    22081 atttggcaat ccactactag taaagctata tctgtctttt ctaaaacatc tagtgattta
    22141 cctattctaa gttcaccaag ttcaccaaca tcatcaagac cagcagtatc tataagaaca
    22201 caaggtccta taggaaggat ttccattggt ctaaatactg ggtctgtagt agttccagca
    22261 atatctgaga ctattgcagc actttgattt gttatagcat ttattatgct agatttacct
    22321 gcatttcttt taccaaagag acctatatgt actcttaccg attgtggagt agaatttaga
    22381 ctcatttgta ctcaccacct taaacttctt tttttgatat actagttttt acagatacat
    22441 gaggtatgtt gcccaattta ccagtcaaac tattaatagt gtccatttcg ccaacaactg
    22501 ctatacatac gattgagaca ccttcttctt cgcaaggaat gcccattctt cctttaataa
    22561 tacctttaaa acctgataca acctcattga atttaaattg acattctttt ggttcttcca
    22621 aaatagcact tataactgca acctttttca taaatatcct cctaactcag aaaatatgtc
    22681 ttaaacaaat ccaaaatcaa aaaacttttc tttgtaaaga aaagtttcta caaaagaaaa
    22741 gttattaatt acacaagtat aatgtgctat attaa
//
LOCUS       DAYAKB010000056        22673 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.056, whole genome shotgun sequence.
ACCESSION   DAYAKB010000056 DAYAKB010000000
VERSION     DAYAKB010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.056"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..597
                     /locus_tag="ACGI3L_002607"
     CDS             <1..597
                     /locus_tag="ACGI3L_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198305.1"
                     /translation="GLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQS
                     LSLIMSCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALH
                     YGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            728..1750
                     /locus_tag="ACGI3L_002608"
     CDS             728..1750
                     /locus_tag="ACGI3L_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD0873 family tyrosine ABC transporter
                     substrate-binding lipoprotein"
                     /protein_id="HFG9198306.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1914..2471)
                     /locus_tag="ACGI3L_002609"
     CDS             complement(1914..2471)
                     /locus_tag="ACGI3L_002609"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HFG9198307.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2477..3553)
                     /locus_tag="ACGI3L_002610"
     CDS             complement(2477..3553)
                     /locus_tag="ACGI3L_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HFG9198308.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3554..4237)
                     /gene="modB"
                     /locus_tag="ACGI3L_002611"
     CDS             complement(3554..4237)
                     /gene="modB"
                     /locus_tag="ACGI3L_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HFG9198309.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4386..5198)
                     /gene="modA"
                     /locus_tag="ACGI3L_002612"
     CDS             complement(4386..5198)
                     /gene="modA"
                     /locus_tag="ACGI3L_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9198310.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5391..6320
                     /locus_tag="ACGI3L_002613"
     CDS             5391..6320
                     /locus_tag="ACGI3L_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFG9198311.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6481..6930)
                     /locus_tag="ACGI3L_002614"
     CDS             complement(6481..6930)
                     /locus_tag="ACGI3L_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198312.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7133..8005)
                     /locus_tag="ACGI3L_002615"
     CDS             complement(7133..8005)
                     /locus_tag="ACGI3L_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9198313.1"
                     /translation="MYNSSVGLEQLIKNEDIVKIFSERKDRPLEKLKNYKTSELMIQS
                     SNNYKLESLFITSNIKTRDTMILVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGN
                     SGGDNYTFGLYERYDLDSLVKFVKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVD
                     FYILDSPYSEMKDAIRMGVLEKRIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVE
                     KSNVPILFIHGTKDTVCNYQNSKKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNK
                     IFKFIDSNVLSDKS"
     gene            complement(8318..9172)
                     /locus_tag="ACGI3L_002616"
     CDS             complement(8318..9172)
                     /locus_tag="ACGI3L_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HFG9198314.1"
                     /translation="MKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKEVP
                     SKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDIEE
                     IEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCDKI
                     IKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLNTI
                     KEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEEEE
                     EKYRRIFK"
     gene            complement(9495..10823)
                     /locus_tag="ACGI3L_002617"
     CDS             complement(9495..10823)
                     /locus_tag="ACGI3L_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFG9198315.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(10971..11300)
                     /locus_tag="ACGI3L_002618"
     CDS             complement(10971..11300)
                     /locus_tag="ACGI3L_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9198316.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11324..12613)
                     /locus_tag="ACGI3L_002619"
     CDS             complement(11324..12613)
                     /locus_tag="ACGI3L_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9198317.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(12629..12955)
                     /locus_tag="ACGI3L_002620"
     CDS             complement(12629..12955)
                     /locus_tag="ACGI3L_002620"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9198318.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(13090..13719)
                     /locus_tag="ACGI3L_002621"
     CDS             complement(13090..13719)
                     /locus_tag="ACGI3L_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198319.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(13934..16591)
                     /locus_tag="ACGI3L_002622"
     CDS             complement(13934..16591)
                     /locus_tag="ACGI3L_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198320.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAANTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(16950..17894)
                     /locus_tag="ACGI3L_002623"
     CDS             complement(16950..17894)
                     /locus_tag="ACGI3L_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198321.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIDVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(17887..18912)
                     /locus_tag="ACGI3L_002624"
     CDS             complement(17887..18912)
                     /locus_tag="ACGI3L_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198322.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(18987..20555)
                     /locus_tag="ACGI3L_002625"
     CDS             complement(18987..20555)
                     /locus_tag="ACGI3L_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9198323.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(20668..21579)
                     /locus_tag="ACGI3L_002626"
     CDS             complement(20668..21579)
                     /locus_tag="ACGI3L_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198324.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(21563..22549)
                     /locus_tag="ACGI3L_002627"
     CDS             complement(21563..22549)
                     /locus_tag="ACGI3L_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198325.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
BASE COUNT         7317 a         3951 c         2549 g         8856 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaagta ttattaaata aacataactt gtctaattta
       61 gctgaacaca gaagaactca aatagtaagt agagtttttc aagacccaag tcttggaact
      121 tgcccttcta tgactgttag agaaaacttg tctttagctc ttaacaaagg aaaactatta
      181 aatctaagaa aatgtcttcg ttacaaaaga gatttcttag aaaatttatt ggaaggtgta
      241 tctcttgatt taaaaaaata ccttgatgtt caagtaaaat ttttatcagg aggtcaaaga
      301 caatcattat cactaattat gtcgtgctta acaaatccat cagttttatt acttgatgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa ttgaattgac taataagatt
      421 gtaagggaaa aaaatataac tacacttatg gttactcaca acttaaaaca cgctcttcat
      481 tatggtgata gattgataat gcttcataag ggtgaagttg tattagatgt aaaaggtaaa
      541 gaaaaagaac aattaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtttaaaat
      601 aatatatcta ttgtattaaa ctcggcttta aaataaagtt aaaattacaa taattatggt
      661 tactttgtaa taattcatat gaatatatga acatatataa caataaattt ttgaggggga
      721 tataaaaatg attaataaaa aaagattggc aagtttgatt ttagctggtg ctcttagtat
      781 atctatgctt acagggtgtt cacaaggagg agactctggt aattcaaaac aagaaagtaa
      841 ttctaaaggt aaagaagtta aaaaaattgg tataactcaa ctggttgaac atccagcatt
      901 agatgccact aggacaggtt ttgtaaaagc attagaaaag aacggattta aagatggaga
      961 aaatattgat atagacttcc aaaatgctca aaatgacatg cctactacac aaagtattgc
     1021 gagtaaattt gcatctgata agaaggactt aatatttgct atatctactc catcagctca
     1081 ggcagcattt aatgctacta aagatatacc tatacttatt actgctgtga gtgaccctgt
     1141 tgctgctgga ttagttaaaa ctcttgaaaa gccaggcaca aatgtatctg gaacatcaga
     1201 ttttgtttct gtagacaaag gtttagaact tcttaaaata tttgctccta aggcaaaaac
     1261 tataggagtt atgtacaata ctagtgaagt aaattccaaa gttcaagttg atgctttaaa
     1321 agaatatgca tctaaaaatg gatttaaagt tgttgaaaaa ggtataacta cttcaaatga
     1381 agttaaccaa ggtatttcta gtttagttgg caaaatagac gtattatatg tccctacaga
     1441 taacttagtg gcttcttcta tgcctatagt ctctaaaata gctactgaga ataaaatacc
     1501 tgttatagca gctgaatctg gtccagttga aaaaggtgct cttgcttgtc aaggtatcaa
     1561 ctacgaaaaa ctaggttaca aaacaggtga aatggcagtt aaaattttaa atggcgaatc
     1621 agtatctgat atgcctgtgg ctacatcaga tgatacagat atcattgtta atgaagatat
     1681 attaaaagct ttaggtatgg aaaaaccttc taatgaaaat atttcttatg taaagactaa
     1741 acaagaatag aaagatattt tctatatacg attaatatgc ctgtttctat aaattaattt
     1801 atagaaacag gcatatattt ttattttaat gtattatcta tttaaagatt atatgtaaat
     1861 gctcttaatt tgtttgtata aattttactt gtataaactt tatacaatca tatttattct
     1921 tctattttct ttattactct acatggattt ccaacagcta cagtatttgg tggtatatct
     1981 tttgtgacta cacttcctgc acctattact acattatcac ctatagtaat tcctggtgtt
     2041 atgattactc ccccacctat ccatacatta tcacctattt ttataggaga accatactct
     2101 atgcctgaat ttctaagttg tgcatcaatt ggatgatagg ctgtatagat ttgaacgttt
     2161 ggagctaaca ttacattgtc acctatttca attttacata catctaaaaa aatacaatca
     2221 taatttgcaa agaaattttc gcctacatgt atgttatatc cataatcaca cctaatattt
     2281 tgttctacat ttatttgctt gccaactgaa ccaaatagtt gtcttaaaat atcttctctt
     2341 ttttcatatt catcctctaa agtattatta aacaatctag ttaatttttt acaatactct
     2401 ctttctttta ctaacaattc atcatttgca tagtatcctt tcccagacaa cattttttct
     2461 ttttcagtca tatagtttac tcctttttgt tataattgta tctaaagcaa aataaatatt
     2521 cctgtggaaa atctaaatat attctgtcac ctttcttaaa tctcatttta cttttttcca
     2581 attctatttg aataggtaca cattcgttag ataaatcagt ttttctaaca tatatagtat
     2641 atgtaaaagg attttctaca atgttaatca attcgaaaca taacttttca tttaaatctt
     2701 cattagaatc caagacctta atatgatgct ccctgattcc cacatattct atattatcac
     2761 ctatttctct atttaatgtc aactcgcatc cccagtctgt agcataaata gtatttttat
     2821 ccagtctatt taatttggat atatttttac accctgttat cttagcttct ataaggtact
     2881 ttggagattc aaagagctct tttttaggtc tctttggaag accttctcct ttgttgtaca
     2941 ctataatatc atcacaaact cggtaagctt cttcaatatc atgagtaaca aatagtatat
     3001 ctcccttgta atcttttaac atattcataa gttctttttc catattgctt cttaaatgat
     3061 ggtccaatgc tgagaaaggt tcatctaaaa gtaatatatc tggagatgtt gccaatgctc
     3121 tagctagtgc taccctttgt tgttgaccac cagataattg ccaagggtat ctcccctcaa
     3181 acccatttaa tttaagtata tctaagtacc ttgctactat ttcctttttt tcactcttac
     3241 ttagttttaa aagcccaagt tctatatttt gacttacagt catatgtgga aacaaagcat
     3301 agttttgaaa taaaaatcct acctttctat cttgtgttga taaatttatc ttcttttcag
     3361 aatcaaatag aactctatca tttaatacaa ttttacctct tgttggtttc tcaagccctg
     3421 ctatacattt taatgtcata ctttttccag aaccagattc tcccaaaaac cccagagtac
     3481 ctttttcttg tttaatttct acctttagtt taaaagagga taaatctttt tcaatatcca
     3541 cgtataagct caactatcca cacctctttc ctataatttt ctgctgaaat tccgaccaat
     3601 aatttagtaa taaaatcatt gctatagata ttgctacaat aatcataacc cacatcatag
     3661 ctttattcat atctccgcct tcaacagcaa aaaatatagc tattggcata gtttgagttt
     3721 ttccaggtat atttccagct atcataagtg tagcaccaaa ttctccaaga gctctggcaa
     3781 acgacagcac caatccacca attattccag gccatgctaa tggaactgca atcttaaaaa
     3841 atactttcca ttcattaaga cctaatgttc tagcagctga caacatatta ttatcaatct
     3901 gttcaaaagc tgaccttgaa gttctataca tcataggaaa agacaccact actgctgaaa
     3961 ttacagttgc tgtccaacta aatattaaag tcctatcgaa atttaataaa aactttccta
     4021 taaatccatt cttcccacat agtaataata aaaagaaacc tacaactgtt ggtggcaaaa
     4081 ttagtggaag tgtaaatagt ccatctataa gacccttcca cttacctcta tagttagcca
     4141 taatatatga cacaaatatt cctattacaa aagttattat tgttgacaaa atagatgtct
     4201 taagtgatat ccataagggt gaccaatctg ttcccatctt tccctcctta attttaaatg
     4261 gaaatagtga aactaataac tctattaatt tcactatttc cattttatta taatacacaa
     4321 ttattttcaa ttttcattta tttatatata atttatactt aattacacat aatttatttc
     4381 taagtttatt ctactttttt atatccaaat tcttcaaaaa tcttttgtcc tgactcactt
     4441 aataaaaatt cttcaaattt cttagcagca tctacgtttt tactagcttt aattactgaa
     4501 actggatatg taataggcga atgagttttt tcgtctgttt tttcaactac ttttatctta
     4561 tcattattga cagtatcact gaagtaaacg aatccaacat cagcatttcc tgattgcacc
     4621 catgctaaaa cttcttttac atcttttgca aatactagct tatcttttaa cttatctttt
     4681 aaatttaaat tagttaacac ctcatctgca tacttaccag ctggaacact ttcagcttca
     4741 ccaacagcaa ttttcttcac tttatctgta gtcaaatctt tcatacctga tacactactg
     4801 tcagcagaag aaataagaac taaatcattt tttactaaat ctttcatagt atcagaaact
     4861 aataacttct cttcatccaa agctttcatt tgtttttgac ctgctgaaat aaataaatca
     4921 caaggtgctc cttgttctat ttgttgttgt aatgagcctg atgctccata gttaactgta
     4981 agttttacat ttgaatcaac ttttttatat tcttcttcaa tctttgccat tgcttctttt
     5041 aaacttgcag cagccgatat atttaactct actgaatcac tacttttagt tgttttttct
     5101 tgttttccat catctttttt gtcttcatta ctattgcacc caactgtccc caaagttaaa
     5161 catgcaacta atcctaatat tcccaatatt tttttcataa caatctccct ttttgtaaat
     5221 ttgatacaca ttttaacatg ttttattatg ttttatcatg ttttgttata tatagtttaa
     5281 ttatatatac atgataataa attttcaagt aatttattta cactactttt aaatattttg
     5341 ctacattttc ctttttttaa tgttaaaata accttatatg gaggtggatt atggactcat
     5401 tatcatcttt gacacctgtc gaggtagctg aattattaaa gataacaaaa aatactgtat
     5461 atgaattaat caaaagaggt gaacttcctt cttataaagt agggaaaaaa ataagagttg
     5521 atactaaaga tgttgaagaa tatatcaaca gccaaaaaac tggtaaagta aaggatacac
     5581 atttcaacaa taaaaatata gatataaata ataatttcaa aattattatt tctggtcaag
     5641 atgtaatatt agacatttta gctaggtctg ttgaaaaaaa attggatgga ataagtacat
     5701 ttcgctctta tataggtagt tataatgctt tgtatgagtt atataatggc agagtttcta
     5761 tagcatcatc ccatctatgg gatttcgaaa cggatgaata taatagcact tttgttaaaa
     5821 agctattgcc aggaatacca tgtgtactta taaatctagc ttatagaatg caaggtttct
     5881 atgttgctaa aggaaatcct aaagagataa caacctggga ggatttaaca aaaccaagta
     5941 taaccattgt aaatagggaa aaaggttctg gaactagggt tttactagat ggtaaactta
     6001 gacttctaaa ctttaatggt aaacatataa aaggttatga taatgaagaa ttatcacatc
     6061 ttggagttgc aagtactgtt tctcgtggaa tagcagatgt tggtttggga aatgaaaaag
     6121 ctgctttaca agtaaataat atcgacttta ttcctcttca caaagagcgc tatgatttag
     6181 ttattaaaaa agaagactta caaaatccag tttaccaaac tataattaac ataataaact
     6241 ctcctgagtt taaagctgaa cttcaaggtc ttggcggata tgatttaact gatactggaa
     6301 aaactatagc aaaagtttaa gattaaaatc gcaatctatt ttataagatt tataattttt
     6361 cacaaaattt ataacttaaa cacgaaataa attgcgattt tagtgtctca aaaaatttat
     6421 gtctttcatt ttatcatcca atacaaaata taatataatt aattgtgcaa tcatattata
     6481 ttaatatata tttacataat agtatttttc tttaatgtag attaacatat gatatgtttt
     6541 aaacatcaat ccccttgctt tcttatatat atttggcaac acatatgagt ttaataaatt
     6601 atatacaatg ttgctttctt cttgtatttt ttcaaccaac aagttattta taaaattacc
     6661 tttctcattt tcaataatct cactccaatt tatcttaact tttaatatat atcttcccac
     6721 taggtataca cactctacaa taaataataa aaatacaatg cagtcagtac ctgttgtctt
     6781 atataaatta cccgatacta atggctttgc gaagaaatta taaaaattca aagtatcacc
     6841 cgtataatca aaaagtatta atagcactcc tagaactctc aatactttaa tattcaacat
     6901 gtttttatct ttattatttt tgtttttcat atatactacc tctcttttct ttagatttga
     6961 ttgtaatcta atactaactc ttttatttga ggtataaatg aatttaattg gtagttattt
     7021 tcatttttac tagaaattaa ttcacattac taaacaaaac ttatatttaa acataaaaat
     7081 agcctatcta ttttttaata aatacaaaaa taaataagct actaatattc aattaacttt
     7141 tatcacttaa aacattacta tctataaatt taaatatttt attgaagtat actgtactat
     7201 catgttcaaa tccatcaaca tgaccaatac cttctataag ccataggtct tttttatcat
     7261 gtttaactaa atcatacatt ttcttgctat tttgataatt acaaacagta tcttttgttc
     7321 catgtataaa cagtatgggt acattagatt tctcaactga ctcatatggt tttacatcac
     7381 tgtaccaaaa tccagattta aacttattat ataaatctcc acaagtcacc acataattga
     7441 ttaatatatc tggtattcgt ttttctagta ctcccattct aattgcatct ttcatttcag
     7501 aataaggaga atccagtata taaaaatcga ccttatcatc ttttgaattt atctctgaat
     7561 gcatagcagc tgtccctgcc cccatggaaa atccatgcac tcctaatctt ccttcaggaa
     7621 atttattttt tacaaattta actagactat ctaaatcata cctttcataa agaccaaatg
     7681 tgtaattatc tccaccacta ttaccagtat ttctttgatt ataaactaat acgttataac
     7741 ctttatctaa atatctatat gctaccttta acatttcata gtaactactt ccaattccat
     7801 gaacaagtat catagtatct cttgtcttta tatttgaagt tataaaaaga ctttcaagct
     7861 tgtaattatt agaactttgt atcattaatt cagatgtctt gtagtttttt aatttctcca
     7921 gtggtctatc ttttctctca gaaaatattt ttactatatc ttcgtttttt attaactgct
     7981 ctaaaccaac tgaactatta tacactaatt tgccaaatat ataagataca attaatagga
     8041 ttaatagaaa cacaattgat ataattataa atttatttct taaactaata caatttttaa
     8101 aactattttt catatttatt taccatacaa ttttcctata ttatattttc taagtaatag
     8161 cataattgat tatactattc ttataatttc tattatacct acttatttat taaaaataca
     8221 aattatattt tattaatttt tactacttgt aaattattat cttatacaat gaatttgtat
     8281 tatataataa gtatttttag gattctgtta cataatatta tttaaatatt cttctatatt
     8341 tctcttcttc ttcttcagta aacacattaa atacaacttt taaatttttt tcaggatttt
     8401 cttttagcca tagtctaact ctacttacag caagattagc tgcctctttt tttggataac
     8461 caaatacacc tgtagaaatt ccacaaaaaa caatattttt tatttcatca atttctttta
     8521 ttgtatttaa acatgattta taacaatgaa gcagttgctt ttcttgctct ttacttggct
     8581 gaccaccaga tacaataggt ccaacagtat gtactacaaa ttttgcaggt aaacaataac
     8641 ctctagttat cttagcatct ccagtatatt ctaaatgccc ttgttttttt attattttgt
     8701 cacaatcttc tctaagtcta ggacctgcgc atgaatgtat ctcattatcc acgcatagat
     8761 gtaatggttg taaacaccct aataacttgt tatttgcagc atttactatt gcatctgctc
     8821 ttaaattcgt tatattacct ctccatatgg caatcccttc ctctatttct tctatatcat
     8881 ttacatctac taactctctt tcttcacatt caatcaacaa taaattatgt aacatattaa
     8941 gtatctctgg agcaatttct tttggtggat atacattcaa aagtcctcta agtatatctc
     9001 taggcttaat ttcatcattt gataaattgt atattttaga aggaacttct tttgaaaaat
     9061 atgcaattaa agtgtttata ttttttcttc tttgttcgtc agttagaggc ttgatagttt
     9121 tatcaaaatc ctcaaataaa tttacatcat cagcataatc tctccacttc atagccatct
     9181 ctccattctt gtattttaga cttaaaaata attatgtatt tatgtacata tttatttatt
     9241 tctataaaca cctacataaa tcctgttaaa agtgtaaatt ttttattatg caacttctct
     9301 ggttatttct attgattgat agtaaattat tgtacctaaa tttaatccaa ctaacaagta
     9361 actaaaccta ctttcctaac tgcaaaatac actatgtttg ccacttgtat ctcatttgta
     9421 aataaataaa gtccctacaa atacattaac taggctatgt actaaactgt aggaacttta
     9481 aaaatatatt attcttaatt aagttttggc caataatttt tatttgcttc tattaaatca
     9541 tctagtaatt cttttgcaac tgttgcacta ggaactgtct tagatagcat aagtgcttgc
     9601 cacaatttat tataagactt ctcaatccaa gcatcaacta ctaatttttc aactgctaat
     9661 tgttgttcta ttaaaccttt ttggaatgtt ggtattttcc ctattgataa tggttcatac
     9721 ccgtcttttc caactataca tggaatttca accatagcat catcttgtat attttctata
     9781 gctccattat tttgaactat caataacata cgctcctgtg tattaaaagc tagagctgta
     9841 gctaaatcca ctataaactc tgcatgtatt cctatcttaa gcccactgcc cttagaatgt
     9901 ccttgctttt ctatcaatgc acatgaacca aaaacttctt tttctcttcc atcaataact
     9961 tcattggcac gagtataatt tacatcagaa tgatttacaa cataatctgg aaatagatag
    10021 tactttaagt aactacttgg tattgtagtt aaatctgttt ttactatttc tttagtaaat
    10081 aaattagttt caaaccaact atctttcttg tcatttttca ttccttcttc accatttata
    10141 aaaccatatt cttttatatg ttctactaat tttggtaaaa gttcatttcc ttttttatct
    10201 ttaattgaag tataccaacc aaagtggttt aatccaaagt atcttatatc catatgttta
    10261 cgagatttga gtcctgcaat ccttgctata ttatgttcca tacctattgg catatcacaa
    10321 atatttatta ccctagaatt aggtctcaac cttctaacag cttccgctat tattgatgct
    10381 ggattagaat aatttaacat ccaacaattt ggagaatact tttccatata atctatgttt
    10441 tcaagaacac cttctataga cctcattcca taagctattc cacctggtcc acaagtttct
    10501 tgaccaacta ccccatgttt tagaggtatc ttttcatcta gttctctcat ttcaagtttt
    10561 ccaactctta tatgagctaa acaaaaatct acatctgtat aagcctcttt agggcatgtt
    10621 gttgctaaat actctatatt agggtccttt tcctttatta gtatttcaca agctttagct
    10681 accttatttt gtctttcttc atcattatca tataatttga ttgctcttaa tggtaaccta
    10741 tctaagttat ctagcaacat taatatgatt tctggggtat atgtacttcc tcctccagct
    10801 attactactg aaaatttttc cataataata tctccttttc tatttaaaaa tttactgtat
    10861 ttataaataa atttataaat actagtactt taaagtaaaa gggagttcat ttattaaatc
    10921 tattgattta ataaactata gccaaacttc aagcactatt tacaagaaat ttaattctta
    10981 ttaattcttg ggtccatcat ctcaaatata tctacaagtt cagatactaa agaatgagca
    11041 aataatgcat ttgaataatg gtcttcagag tgcacaacta aaaaatcagt cccactatct
    11101 tcactattca tagcatttga tagtaattct aaatgatgct ttgatgctgt ttgtattttc
    11161 tctgaggctg aatttaaaag gtgttttgct ttattgtagt cacctttttt tatttcctta
    11221 agagacatca ttacatcact tttagcatct cctgcttctg atattatact aaatactttt
    11281 tcttccattt caggtaccat atccttctcc ttctaatgac ttgttaaaaa tcaaagctat
    11341 catcatctaa tgttgtagct aattctgcat ttttatttaa ttcttccttc tccattatct
    11401 taaagaatgg ataatatatc aaggtcataa gtattatact tgcaaatact aatacgattg
    11461 ccttccaatc taatgtcatc aaaaatgctg caacccctgg aggtaaaaag cctggtggtt
    11521 ctgcaatagg taatcctact aatcctactt ttaatgccat aaaattaagt gctccaacca
    11581 atacaggtcc aaatacaaat ggtacaaaca tatatgggtt cataactatt ggtgttccaa
    11641 atattaccgg ctcatttatt ccaaatagtg atggtaaaat cacaactttt cccatactat
    11701 taaaactctt acacttactt cttgacataa ggtacactaa tcccaaagtt atccctgaac
    11761 cagttacttg caagaaacca tagtaaaaac ctattgtaaa cacatatttt gggtctcctc
    11821 ctgctgctat taacgttgca ttttctgcca tatatgtagc tgctattggc atccatatac
    11881 ttgaagttat tgctgctcca tgaagcccaa agaaccataa taattgagtt ataaatagta
    11941 ttatagttac tgcaaaaaca ttatctacac tgcttatagc tggtgctaag aaattcatta
    12001 taatagctgg taatggttga cctgagacat ttttagttat tgctgctatt gctgtaaata
    12061 acattataca tactatcatt ggagttaagt ttctaaaact tttatttact acactaggta
    12121 cttcttttgg aaatctaatt acgagatttt tatcattcat aaacttagta atatcaacta
    12181 ctaaaagtgc tactaatata cttacaaata aaccttgtgc atctaaataa cttgtatcta
    12241 atacaccatc tactacttgt ccacatacaa caagttgtgc aacaactgct gtcataccta
    12301 tttctacatg attaagatta tattttttag ctagtgcctg agctataaaa aatgctgaat
    12361 atatagataa taaactcata gtaaatttat tagggataag taatgtatcc atattttcag
    12421 ataataatgt ttttgcactt ccttcaggta acatattgtt taatgccata aataacatac
    12481 ttaaagaacc aacaattatt attggggtaa tgcttatcat accttctttt atagcttgaa
    12541 gatgcctttg tttttcaatc ttttgtgcta ttggaagaag aaatcttctt aaattatttt
    12601 gaagtgcttc catttttatt ccccccaatt atctattttt atataattcg attgccgact
    12661 tcataacaga aggagcatcc atacgaccat aatgcttagt atctattaaa ccaactgcta
    12721 ttttgtaatt cttacaagct tcaactacat catcttcctt aaacctaatt tgtggtgcta
    12781 caagtactac atcggtatca ttagcttcaa tgtatgattt taaattttca aatgatgttg
    12841 cctctatatt tatagtttta gtttttaact tttcatgctc actacaaaaa cttttcatct
    12901 tttccacaag tacacctgtt gaagctccat ttgcacatac taataaaata ttcataatta
    12961 ccctcctaca atatctaacc tcttttattt tctaattttt tatcagccaa ttcttactct
    13021 aattcctatc agtttttact ttaattctta ttattttatt ttaattctta ttaatattta
    13081 ctctaattct tagtactgcc aatgattaaa cttgaaagcc gtatctataa cttcttcttg
    13141 cttatatttt tctaatattt ttaagtatct ttctttataa tcattatcta cttctttttc
    13201 tggtattact atactagctt catttaaaaa gtggaatgaa tcccttccca tttctaatcc
    13261 tctatatgta tgcttgtcaa gtgccacgtc cataacttct ggaactttac ccattgcaaa
    13321 tccttttata attatatttt ttaataaatc acttgatcta tctttctcac atgcacaaag
    13381 atatcttatt gcatgtatga aaaataaagg tctgtctcca tctgcatatg aatattcctt
    13441 tcttacttga tttaaattat ttatgattat tacagctgat gggtccccca ttcctatatc
    13501 ttcaactgat attgtaagta tccttctcca tagcttatct tctaattctg gtgatgatat
    13561 atatagttca taagcaaatt cacaagcttc ttccaccata tttcttctta tagctttttg
    13621 aaatgacgat attatttcat ctgcactaaa tccgtttctt gtagtcattc ttgcccatgg
    13681 gtcatttgcc tttttatctc ttaatatttt atcttgcata ttatttactc ctttttattt
    13741 aaattttaat tatttatatt actcatttaa taatataagc aagtattatg ccagtttttt
    13801 tagacacttt aaaacactgt tatttcaatc atttttatca tcaaaactta gatactttgt
    13861 ctaagtatat ttatatgtgt ctaatattaa tattatttta gactaaaaaa aattaccaaa
    13921 taagttttta tactcattgg taatcttttt cgattatttc tgcatattct aatattaata
    13981 atatttgata gcactctttt tcattaattt ctatattata ttttttatct aattgagata
    14041 ctatatcttt tattttgctt aggctcttgt gataatcaag tgttttttct ttatcaagct
    14101 tttcaatttc tctagtattt ccaatcaatc catctaccat gaaagctaaa tgcatcataa
    14161 gtccaattac tttatcgtat ttcttttcta tattaaatac taaaaacaat tcatcagaca
    14221 catattttat atctttaaat atcctattat aattagagct ttttaaggat gtctttaaac
    14281 cttcaactac atcatcataa cctatactta tctttataat attttttaat ttattgatat
    14341 tttcatcctt atctatatct tttttgctaa tatagtcaat tcctctaata ttaattcttt
    14401 gttcattgat tactgcaaca atattactac tttctttaag tttcgtaata tttaaactta
    14461 aatctttttc tgttttatat gggacagata taatatctat tccatctaag tacctactca
    14521 tcttttcttc taatattttt cttgttttat tatctacacc ttctgaaaca tgtgatgcta
    14581 taataattgt tttagacaga ttttctttat tttgaatttc attagttcca aaatagtact
    14641 ttctcgtgtt agttatagag ttgtatacgt catttaaagg taatcccata ttggccttct
    14701 gaactgcttc taacacagtt aatgttgtca ccataggaat tactcttact ccacactttt
    14761 tttctttctt tataatttca tcaaaagagt ttaatgaacc catatctgta aatagtaata
    14821 catctttatt gtctatatta ttaattaaat ttttaaaatc tacaataact tcatcatagc
    14881 ttttatctaa cttcatatcg aaagaaatag cactgcactt tccaataata tcaccaactg
    14941 cttttaccat actacttgct gtagtttctc catgcatagc aactataata ttaatgttat
    15001 tcactatttt attttgttca tcttgtttag cttgtactat gaataatgta atatatgcta
    15061 cagtttctat agataaaaat aaatcaaatt cattttcaat tattccaact atttttagtg
    15121 ctgttttaaa ttcacttctg ttatttcttc taatttgatt caaatctatg ttgtttgtag
    15181 agctactttt atccaatacg ctttttatat aaattgccat tgacttaaat attgattcac
    15241 ttatgtctat ttcttcatct tctttaataa tttgtcttat tgattcacac atgcttttaa
    15301 acttaacatt attaaataga gaagcatctg ctatattcat ttctacagat ttattaagat
    15361 tagtatttgc tgcattaata atatttatat cattgtagtt aataacttct tcttctccta
    15421 atgacgtaaa tacaaaatat tctattccat gtgttataac ttcatctgct ttaatagact
    15481 tctctctata atcatcactc acttcattta tagatttatc aaaatatttt ttctctatat
    15541 aaactggttc tttattatct cttttatatc ttaggtatcc atttgcaaca gctaatttta
    15601 tatcattttg aagttgacct acattatttt tacaatcata aagtaatagt gatttaatta
    15661 tttctttatg tacttttatt gaaatagaaa tactttttga ttcttccttg aaaaaatttt
    15721 tgactaattc cattctttca atcattgtcc tatctctcag tgatggtatt tctattttca
    15781 ttggtattct tctattgaat gtatctaata gtgttgatgt cggattttct gtagtagcac
    15841 atattattaa taccttagac tctctttctt tcgttgcatc tcctagtctt ttaaatgttc
    15901 ccttatctat aaaagtaaac aacatttctt gaccttctgc tggtagtcta tgaatttcat
    15961 ctaaaaatag tatccctcca tttgcaattt ccaaaagacc ttttctggaa gattctgcac
    16021 ctgtataagc tccttgttct accccaaaaa tatgtcccat aagtaattgt gcattattag
    16081 cataatcagc acaattaaat gttacaaaag gagctttatt ttttctaatt ccactatcta
    16141 tagaataatc gtacatatat ctagcaatca tactctttcc tactcctgtt tctccataga
    16201 taatagtatg aagtccattt gtaggataga gcattgcgac cttgcatttt tctattatag
    16261 gtcttaaact atgttcttta cctattagtg tttcaaaact atcttttttt attttgtttt
    16321 ctacttttgt tccttttttt atgccaagca actcactttg tgtatcaagc aattcattct
    16381 tgttaaggtt aagatttgca gggatataat acacaggtct tccttttatc ttcgtaacca
    16441 taccctcatt gaataattgg tttaaatatg tacttatatt gtttcttgca attcctgtct
    16501 tttctgataa ttggttagct gtaatccctt tttcattttc cctatatgat gattctaaaa
    16561 ctttcattac tttatctttt ttatatatca ttacaagctc ccctacatta tagtatttta
    16621 ttaactaaaa cccctataca cactttattt tttaataaac tcttattctt taactaaggt
    16681 tataatttat caaactttcc ttactttaaa ttatagaaaa ttattgtaga aaaaataaga
    16741 ttattgctca ttttttctac attactattt ttaattttat agtactttct taacaacata
    16801 ctttacttgt ttttaatttt attatatttg aatttattat atttgaaaag tagaaataaa
    16861 aaaccctatt ttggagtagt tttaaaattt ctccaaaaat agggttttag tttgtatttc
    16921 aaataaatac ctgttcaagt atttttatac taaacaactt ttaaattttg ttgatattta
    16981 tttatttctg atttagaaga atatacaaaa tgtccatctg aaacatcaat ccaacttaat
    17041 gacttttcat ttgaacaatc atatccatta gaattatact ctattctatt tcttgactta
    17101 gcatatctag ggtcaggaac aggaattgca gaaagtagtg attttgtata tggatgaata
    17161 ggattattat acaattcatt tgaatctgcc aattctacta attttccatt atacataact
    17221 cctatacggt cactaatatg tctcaccata gataaatcat gagctataaa taaacaagtt
    17281 aaattctttt cttgttgcaa ttttttaaat aaatttacta tttgtgcttg tatagacaca
    17341 tccaaagaag ctataggctc atcagctatt ataaattctg ggtctactga aagagctcgt
    17401 gctatgccaa tacgctgtct ttgtccacct gaaaaatcag atggatactt atttgcataa
    17461 cttctatcaa gtcctactag ctttagcatc tcatatactt tattcattct atctgtttta
    17521 tttttacaga taccttgaat ttttagtggc tctgaaatta tatctgcaat tgtcatacgt
    17581 ggatttaatg atgaagtaga atcttgaaaa ataatctgca tacttttgtt tacatctttt
    17641 tttataaatt tgtacgtttt tttatctgat atgcaatttc ctttgtaaat tacttctcca
    17701 ccagtagatt catgtagtct tattatagtt ttaccagttg tagattttcc tgaacccgac
    17761 tctcctacca atccaaatat ctcaccctta tatatatcaa aacttatatc atcaactgct
    17821 tttacagtag tacttttgtc caaatgaaaa tattgcttta agttttttat ttccagtatt
    17881 ttttctctat tcattagaaa tcacccttcc acaatttact ctaactggta catctacttc
    17941 aggtgcatct gggtgcaata accaagttgc tgcactatgt gtatcattaa ttttaaacat
    18001 tggtggctct ttttcataat ctatcttaag tgcattttta ttccttattg caaaagcatc
    18061 tccttttggt gggttcaata aatttggagg cattccaggt atattatata aatagtcatc
    18121 ctgcgaatct aaagtaggta atgaacccaa caacccccaa gtatatggat gtctagggtc
    18181 ataaaatata tcctctacag ttcctatttc tacaatcttt cctgcataca taactgctat
    18241 tctatcagct atagttgcaa ctactcctaa atcatgagtt ataaatatta ttgacaaacc
    18301 tattttatgt tgtaaatcct ttattaaatc aattatttga gcttgtatag ttacatctaa
    18361 agcagttgta ggttcatcag caatcaatac atctggatta caagcaagtg ctatagctat
    18421 tactatacgt tgtctcattc cacctgaaaa atgatgtgga aattgtttaa atcttttctc
    18481 aggattatca attccaacca attcaataag ctctatggct ctcttttttg cctcactttt
    18541 acttatacct tgatgaatga ttacagcttc tgcaatttgc tttcctattg atatagttgg
    18601 attgagagat gtcatagggt cttgaaatat cattgatata ttctttcctc ttatatcttc
    18661 catctctttt tcagacttct taaccaaatc acttgattta agtaaaacct ctccattttt
    18721 aatatatcca ttgtatggga gtatcctcat caaactctta cacagtacag atttcccaca
    18781 accagattct ccaactatag ccaatgtctc accttttttt agattaaaag atacatttct
    18841 tacagcctga acttctcctt cttctacttt aaaacttaca gatagattat taacctccaa
    18901 taaatgttcc aaaaaccatc aacccctatg ctattcaaac cttagggata tatttttatc
    18961 cctaaggttt ctaattaatt tcagtattat tcaattgtcc agtcagctat gttccagaat
    19021 atacctacac catgatgacc taaaactgta tcaggtgtta atccttttat gtttggtttt
    19081 ccaacatata ttgcatctat ataagcaata aatgtataag gcatatcctt agtcatttct
    19141 acttggaatt gtttatataa ctttaatttt tcatctttat cttctgtttc tcttgctttt
    19201 tgaagtattt tatctatagt aggattagag taagcactgt aatttgcacc tttatctgtt
    19261 ccaaatactt tatatgtatg gtcatctggg tcaaatggac ttccccaacc tattaaatga
    19321 gcatcttgat tagcccaatc tgtttcagtt acaacaacag ctttagcatc aacaccaatt
    19381 tcttttaact gttgtgcaca tattttagcc atatcaactc taacttggtc actctcacct
    19441 gctgttatct cgaaagctaa cttagtacct tctttttcat agattccatc agaacctaat
    19501 ttccaaccta gcttttcaat ttcttgttta gctttttctg gattatattc aaacttttct
    19561 atatcaggat tattatatgg tcccatttgt aaaggtgaat atgctggtac accatgtcct
    19621 aataatacac tgtcaactat tgcttttcta tctattgcat agcttaaagc atttggtaat
    19681 cctttagctt ttttatcttt aaagaattta gaattaaaat tgtataatat acctctatag
    19741 tcggctgttt tcattatatt tactttaaaa ttcttttcgt ctttttcaaa gttagacata
    19801 tctttaggag ttatttgagc taggtctaat tctcctgatt ttaattgcat tgccttagcc
    19861 ttatcatctg gaacaatctt aaagactact ttatctaatc ctggttcttt tacaaaataa
    19921 tcactattct taacaagtgt tatactttga cctttgtccc atttttcaag tttaaatggt
    19981 ccagtaccta ttggtttttg attaaattca tcagtagcta tatccttacc ttccaaagca
    20041 tgttttggta atactcctac tgttaaataa tcaagcattg ctgtatttgg agcttttaaa
    20101 gtaattttta tagtattatc attaaccaca tcaatttttg ttatatcttc ataatttgat
    20161 gctatctcag aagcattatc tggattcatt atagtttcta ttgtaaactt aacatcattt
    20221 gctgtaaatt tttctccatc atgccactta acatcatctc ttaaattaaa agtatatgta
    20281 tttgttgcct catcaaattt ccagtccttt gctagacaag gaaccacctt attattttca
    20341 tcatgagctg ttaatccatt aaatattaac gaatttattt ctccatgttc atatagtgca
    20401 ggatttatac ttgtatagtc attacttcca taaacaagca cctttccatc tttaggcgta
    20461 tctgccttct tatctttgtc tcctccacta gaacaacctg ccattagact aagtatcatt
    20521 actaaactta aaacttttaa cttctttaat ttcatgatgc tccccctttt gctttttata
    20581 aaatattttt caaagctttg accccattta tttaaataga tatttcaaat acctcagtat
    20641 ttgcttattt aatactcaaa tgctgattta taaattacta gattttttat tattattctt
    20701 tcttatataa ttacctatat ttgttataca caccaatgtg gtaaccaaaa atatacccgg
    20761 aatcagtata atccaccatc tatttgaaag taatgcttcc tctgacaaag ataacatact
    20821 tccccaagaa acaatttcta ttggtaaacc aattcctaaa aagctaagtg tcgattcagt
    20881 accaatagct gcgcctatgt ttgttacaac catgaacatt attgatgcca caaaatttgg
    20941 aagtaaatgt tgctttaata catagaagaa tcctcctccc atgctcttag ctgctagtat
    21001 gtattcgcta ttttttattt gtctaacttc tgttctcact atcttagata tattcatcca
    21061 acttgttatc cctattacta tggacataga tactggattt gaatttccaa gtatagcttg
    21121 tacaaatatt ataattaata ttgaaggtat actaagtatg atttctgtaa acctcatcat
    21181 tgcatcatct acaagttcag atgctgaacc acttatacta ccataaacaa ttcctataac
    21241 agttgatatt acagtggaaa atagtcctat aaataaagat atttttcctc cataccatat
    21301 catagaatat atatctctac ccattgagtc tgttccaaat aaaaaagttt tatttggagc
    21361 taaattagaa cttgctaaat ccatgtatgt tggttcatgt gtcattataa aagatgagaa
    21421 tacacttcca atgactatga ttgataaaat aataattgat atatatggta attctttaat
    21481 ttttttagat aaggttttct ttgtttctat atgttcatct tctgctacta aaatataatt
    21541 ttctcctaca atttcaaaat cactatattg tggcttcatt agtatcacct ctatcatatt
    21601 tcattctagg gtctatttta ttgtttataa tttgagctaa catattccca aatactacta
    21661 aagcccctgt tattaagcat aaaactaata acatattata atcatgatac tttgcacttt
    21721 caaaacaaag tgttcctaac ccaggataag aaaaaacttt ttcaactaca taagttcctc
    21781 ctagtatatg aggtatcgaa atggccatta tactaatata tgatggcatt atatttctca
    21841 ggcaatgctt aaaaacaata gttctattat ttaaaccttt tgctttacat aaaagcacat
    21901 aatcttctct tatttcctct agtaatttat ttcttatcat atatgtgtaa taccatagat
    21961 ggcttaatat aagtactgta agaggtaaga ttagatgtga tatcctactt aatatactgg
    22021 actcttctcc cattgaataa gcaccactac ttggaagtat acttaagttt atactaaata
    22081 taagtatgag tactaaggca acccaaaatg atggaataca gttggttatt gttcctaatt
    22141 tgcatatgat tctatcaatg agcttatctt catgtaatgt acaaaatatt cctaacaata
    22201 aggctagcac aaaggtaagt atatatcctg aaccacctaa tattatagtg tttatataga
    22261 catcatttat aacagaagta acattttgtt tatatttaaa tgaaattcca aattcccctt
    22321 ttgatgcatt tgaaatccat tttatatatt gactgtatat tggttcatcc aaaccaagtt
    22381 ttttcatagc attttctttt tcttgtgtac tcattctttc tactccatcc ccatagtaag
    22441 agattaatgg gtctcctgga gcaagtcttg ccatgtaaaa aacaataaaa gataataaaa
    22501 acattactaa aataaactgc aacaactttt tcagtatatc ctttaacaaa ccccaacccc
    22561 cctttgttgc aataaaaaaa accacataaa agcaaacgta aagtaacgtt aaaaccttcg
    22621 tggttccatt atcattaaac aaaattaaat tttctatatt tatctatgag tta
//
LOCUS       DAYAKB010000057        22105 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.057, whole genome shotgun sequence.
ACCESSION   DAYAKB010000057 DAYAKB010000000
VERSION     DAYAKB010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.057"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            278..505
                     /locus_tag="ACGI3L_002628"
     CDS             278..505
                     /locus_tag="ACGI3L_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9198326.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            531..2651
                     /gene="feoB"
                     /locus_tag="ACGI3L_002629"
     CDS             531..2651
                     /gene="feoB"
                     /locus_tag="ACGI3L_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFG9198327.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKNSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(2784..3602)
                     /locus_tag="ACGI3L_002630"
     CDS             complement(2784..3602)
                     /locus_tag="ACGI3L_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9198328.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            3821..4093
                     /locus_tag="ACGI3L_002631"
     CDS             3821..4093
                     /locus_tag="ACGI3L_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198329.1"
                     /translation="MKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKAVKLE
                     IFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   4261..4487
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4328..4356
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(5146..7239)
                     /gene="pdcA"
                     /locus_tag="ACGI3L_002632"
     CDS             complement(5146..7239)
                     /gene="pdcA"
                     /locus_tag="ACGI3L_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdcA"
                     /protein_id="HFG9198330.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SVQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     gene            7883..8815
                     /locus_tag="ACGI3L_002633"
     CDS             7883..8815
                     /locus_tag="ACGI3L_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like and DUF2520 domain-containing
                     protein"
                     /protein_id="HFG9198331.1"
                     /translation="MGFIGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKT
                     KIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSK
                     KAGALIYSIHPIFAFSNKNTDIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRD
                     KDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNG
                     FTKALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNIT
                     IENAIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            8790..9617
                     /gene="panB"
                     /locus_tag="ACGI3L_002634"
     CDS             8790..9617
                     /gene="panB"
                     /locus_tag="ACGI3L_002634"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HFG9198332.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIIKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            9636..10484
                     /gene="panC"
                     /locus_tag="ACGI3L_002635"
     CDS             9636..10484
                     /gene="panC"
                     /locus_tag="ACGI3L_002635"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HFG9198333.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSIFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            10895..11077
                     /locus_tag="ACGI3L_002636"
     CDS             10895..11077
                     /locus_tag="ACGI3L_002636"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198334.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            11904..12818
                     /locus_tag="ACGI3L_002637"
     CDS             11904..12818
                     /locus_tag="ACGI3L_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HFG9198335.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            13208..13855
                     /locus_tag="ACGI3L_002638"
     CDS             13208..13855
                     /locus_tag="ACGI3L_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HFG9198336.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(14022..14591)
                     /locus_tag="ACGI3L_002639"
     CDS             complement(14022..14591)
                     /locus_tag="ACGI3L_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198337.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(14596..15495)
                     /locus_tag="ACGI3L_002640"
     CDS             complement(14596..15495)
                     /locus_tag="ACGI3L_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9198338.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIIFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(15506..15655)
                     /locus_tag="ACGI3L_002641"
     CDS             complement(15506..15655)
                     /locus_tag="ACGI3L_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1871A family CXXC motif-containing protein"
                     /protein_id="HFG9198339.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(15648..16232)
                     /locus_tag="ACGI3L_002642"
     CDS             complement(15648..16232)
                     /locus_tag="ACGI3L_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HFG9198340.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            16621..17946
                     /gene="cdeA"
                     /locus_tag="ACGI3L_002643"
     CDS             16621..17946
                     /gene="cdeA"
                     /locus_tag="ACGI3L_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HFG9198341.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIFALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(18041..18835)
                     /locus_tag="ACGI3L_002644"
     CDS             complement(18041..18835)
                     /locus_tag="ACGI3L_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198342.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMIIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(18836..19711)
                     /locus_tag="ACGI3L_002645"
     CDS             complement(18836..19711)
                     /locus_tag="ACGI3L_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9198343.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLSFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(19715..20083)
                     /locus_tag="ACGI3L_002646"
     CDS             complement(19715..20083)
                     /locus_tag="ACGI3L_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198344.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(20266..20925)
                     /gene="deoC"
                     /locus_tag="ACGI3L_002647"
     CDS             complement(20266..20925)
                     /gene="deoC"
                     /locus_tag="ACGI3L_002647"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFG9198345.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(20961..>22105)
                     /gene="murJ"
                     /locus_tag="ACGI3L_002648"
     CDS             complement(20961..>22105)
                     /gene="murJ"
                     /locus_tag="ACGI3L_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFG9198346.1"
                     /translation="GIIFIGITSVMSAFLQIKENFIVVGFGSIPYNIVIIISIMLSTI
                     FGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSLIKLLALLSPVFIGVA
                     VNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIVSVMYPMLSKLSAENN
                     QKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAFDARATQMTATALIFY
                     AVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLVLIKPMAHGGLALATS
                     SSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVLSYFTYKFIFGILGVG
                     TFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLHLKK"
BASE COUNT         7927 a         3186 c         2673 g         8319 t
ORIGIN      
        1 ttgaattgat atttaggtat ttgaaaatac cttacataga gtcagaaggc ttttgctttc
       61 tgactttttt attatcaaaa ttcaataatt atatggattc aaagtgttaa tttttattct
      121 atattctact ttccccaaaa gtaagaatta tacccaactt tgtatgatag gcatcttgcc
      181 tatctttttt ttgtaaaagt aacaaggtaa taatataatg catagtttaa aataagaaga
      241 ttagcccagg ctaaatttca agcatggagg tgctattatg aaaaacctta acgatattca
      301 agtgaaaaaa actgtcaaag ttgaagatat attatctagt ggtaatttaa gagaaagaat
      361 gttagcgctt ggtcttacta gaggagctgt tatagatgta gttagaaaag gtccaaaaaa
      421 taatttaact gtctataaaa tcagaggtag caagatagct ctacgacaag aagaaagtag
      481 cttaatatta gtttctgaca tttaaaaatt tctagcagga ggatattaat atggggttga
      541 cacataactc aactaaaatg agttctttaa aagacatgtt tgatatagac aataaggaag
      601 accagtttgt aattgcattg gctggcaatc caaatacagg taaaagtact gtatttaatc
      661 atcttacagg acttagacag catactggaa actggccagg aaaaactgta gctacagctc
      721 gtggtaattt taaatataaa aataccgaat atgcattaat agatttacca ggaacatatt
      781 ctttatttgc cttatcacaa gaagaaattg tagctcgtga ttttatatgt tttggtaatc
      841 cagatgcagt aatagtagta tgtgatgcta catgtcttga aagaaattta aatttagtat
      901 ttcaagtgat ggaacttaca gataaagtta ttttgtgtat taatttaata gatgaagcta
      961 gaaaaaaagg cattactatt gataaaaaac ttttagagga ttctcttggt attccagtta
     1021 ttttaactgc tgcaagaaat ggctctggta tggatgaact attggatact ttaaatgatg
     1081 tatcttttga caaatataaa ttaaataata aacctgttag atacaatgaa aatatagaga
     1141 atgtggtaaa atcaattcaa ccagaattgg ataatattat accaggtata aattctagat
     1201 ggttgggact tagacttatt gatggcgatg aaagtatatt tgaatctatg agtaattata
     1261 tagacaaaaa ttctatagat gctattaatg aagtaaagaa aaagattcca gacaatataa
     1321 ataaacagaa aataagagat gagtttacta aaatcaacta tgattatgct aaaaaactga
     1381 gtgatgagtg ttgttctaat gttgctaaaa aatcaactga tagagaagaa aaagtagata
     1441 aaatattaac atctaaaata tttgggcttc caataatgct cttattatta ggtactatat
     1501 tgtggattac tatagaagga gctaactatc catccacttt attatctaat ttattactcg
     1561 gatttgagcc aagtatttcg ggtatattaa atagtattaa ttgtccatca tggttaaatg
     1621 atatgttggt tttaggatta tacagaacat tagcatgggt aatctctgta atgctacctc
     1681 ctatggcaat attttttcca ttatttaccc tacttgagga ttttggatat ttgccaagag
     1741 ttgcatttaa cttagaccac ctatttaaaa aagcttgtgc acatggaaaa cagtgtttga
     1801 ctatgtgtat gggatttgga tgtaatgcag ctggagttat tggttgtagg ataattgact
     1861 ctccaaggga aagacttata gctatactta caaacaactt tgttccttgt aatggtcgtt
     1921 ttcctacttt gatagctata tctacaatat tttttagctc agttataacc aactctttcg
     1981 tatcaagcgt agcaactgca ctttgcataa ctttactgat aattctaggt gttataataa
     2041 cattgttggt ttcttacact ctttctaaga cgctattaaa aggagttccg tctacattta
     2101 cattagaact tcctccttat agagttcctc aaataggaag aactttatat acctctataa
     2161 tagatagaac aatatttgtt ttaggaaggg ctgtaatggt agccatacct gctggtgtca
     2221 taacttggat atttgcaaat atatatatag gagatttaag tatattatca catgttgcaa
     2281 actttttaga ccctttagct aaattaattg gtcttgatgg ttttatatta cttgctttta
     2341 ttcttggatt cccagcaaat gagatagttg tacctatact tttaatggct tacctagcaa
     2401 ctggttctat gatagaatta gatagcttta gtgctttagg tcaagttctt agagaacatg
     2461 gatggactta tttgacagct ttaaatgtta tgctgttcag tttactgcat tggccttgtg
     2521 caacaacact tttaacaata aaaaaagaaa ctggtagttt aaaatggact gccttaggat
     2581 tcttaatgcc tactatactt gcttttgttg tttgtttttt aacaactaca gtttacaatt
     2641 tatttatata attagtatta actgacagta gacatatatt agagaaacca tttaaaaatt
     2701 tatatacttt attataaagc atagagatat attcaatgat aagtaaaatt acttaacatt
     2761 tgaatatatc tctattttaa ttcttatctg gatacttgga ttgaaatttc agtcatataa
     2821 ttatcttcat tactttcaca aaaaaagtca agtatactct cctcatacga atttccaaca
     2881 attttatatt cattttcata tatatatttt ttcaattttt cgtaagattt atatgaatcc
     2941 tcatattttc caatatgttt tatgcaagca tacattcctt ctggctttac atatagcttt
     3001 ttatccttta tttttttatc tatcttcaaa taaaaacttg atatacttaa atagtcccca
     3061 ttttttatat tttcattact tactattact cccaactcat atccttgata caaatttttc
     3121 gatttacaat aattggtaaa atctattaat tccatcataa aatcactatt actcatatta
     3181 ctcaaatcgc ttgatagaac taaatattct tcaaactttt tggatatata aatttcttca
     3241 ctattcattt tagaaattcc ttcaactgtt atatttattc tattttgcat cttagaactt
     3301 atctttctta gtttttttat tttttctctt atcttttttt cttcttcttt aagcattttc
     3361 acacaaagct ggggagttct attttgtata tactctttta tttcctctaa actcattcct
     3421 atttctctta atgattgtaa tatatcaagt gtatcatatt gataaactga gtaatatcta
     3481 taattatttt tatctttata ttcaggagaa aaaataccta ttttgtcata gaaaattaat
     3541 gtctgcttag atataccaca caatttagca aattcacctg ttgtaaaata ctgtttttcc
     3601 aagggttata cactcctttt ctttttgttg tctatatagt tactatattc tttattattt
     3661 actaaatcaa gtagttatta ttttagaaaa tcaatatggt tttgatttta aagcttaaat
     3721 atcagttaga tgtcagttat aaatatttta ccctttccca tcataaaaaa gatatcccct
     3781 cttaactttt ggatggaata ttatatttat acttgttaga gtgaaaattg taataggtgc
     3841 tacaataaga tatttaatta aacataaagt taattattgt aataaaaaat ctttagataa
     3901 attagagtta aagtacggaa atatagatag agaaaaagct gttaaactag aaatatttta
     3961 tcagtattta atagaacttg aatatataga aatgagttta ttaataagaa gattagatac
     4021 tgcaataaca tcattagcat tagtatctat tataacaata gcatcatatt atttaatcag
     4081 aaaaaatgtg taattatgta agctatttat aataaaacac tgataaaatt aataataaaa
     4141 aggtaatagg atttctatac tacctttttg tttttataat atagtgtaat tttattatat
     4201 ttttgtatgc taatgtaact agataatcat aagataacac attaaaagaa aattatgaaa
     4261 acttacattc tgtatagtta atataaaaca taagtaatat aaatttatgt aaagcaacaa
     4321 aagatagatt tacattccat atagttaata taaaacctta gagaaagcga aaacgtacca
     4381 ttaaaatcaa atatttacat tccatatagt taatataaaa cgttgtaatc atagttccaa
     4441 ttagccactt taacatgcat ttacattcca tatagttaat ataaaacacc aaaataaact
     4501 tagtattttc aacacttaca cgtatacaac tctcctaaat ttgcagtgaa cgagcaatag
     4561 tgcaattgat aacgcttatc atgcactctc aacgccttat atttcaactg ttacgccaaa
     4621 ttttttcaca aatatcgctc actgcaaaat tcctataatt ttattatatc ataaatatat
     4681 tacttttgaa tattgatacc aatttatacc ataataaaag caaaaaaacg taatctatct
     4741 acattagatt taaattctat aacttaaagt tttttacata atatttatgc ttgtttaatc
     4801 aatctaatat atcattcttg tatattgctt ttaatagtct tttttcttaa ataaatatct
     4861 atctgaacaa gcatagttta attaaaaact tttgtattcc cttaaaactg tatctacctc
     4921 ttattatttt atttatgata tattattttt aatctaaaaa tagatatcta tttttattat
     4981 ggttatccct ttttaaaata ctttaatcat atactattcc caatttaaca tccattgaaa
     5041 tgctattttc ttatattgca atttataatt gatatatctt caatataata atttaatgta
     5101 tttttgattt taaagctttt cagtgatatt attgataaat tagaattaat tatctagctt
     5161 taaaaggtca aagatttctg ttgctgtctg cggttttcca aataaatatc cttgtatgta
     5221 atctggcttt atttgtttaa ctaaatcata ctcttcttgt gtttctacac cttctaaaca
     5281 tacttttatt cctacatcat gacaaattgc aacaataaaa tgtataaatg tagcatcaaa
     5341 cttactcttt aatatatctt taacaaatac tctatcaatt ttcactatat ctattggaga
     5401 aaattttaaa acttctagag acgagtatcc agtaccaaaa tcatccatag caatataaat
     5461 tcctaaatct tgtaaagcct taaatttaaa ctgtaaaata ctcatatttt gtactgtatg
     5521 actttctgtc aattctaaaa caagattttg ataaggaaaa ttttcatcat ctataatttt
     5581 tactatatct tcaataaatg tgtcttctaa tatttgaaca gctgaaacgt ttacactcac
     5641 tttaaaaaaa ggatagtaat caatccattt cctaaaagta cgtaatgcca ttcgaagcac
     5701 ccaagcccct acaatattta tcatatcatt ttcttctaat attggaataa attccaaagg
     5761 agaaattgct ttgcatttgt cattagtcca ccttaaaaga acttctacac ctattatttt
     5821 atgactttct gtatctactt gtggctggaa tcgaagacta aaccccctaa aatcatcatt
     5881 aattgatgcc tttaaatccc gcatcatttc taatgaatac attttatttt ttaatatttc
     5941 ttgggagaaa aaaacaagcc tgtttttacc atgctctttc gcatattgta aagagtaact
     6001 agcacactta taaagttctt ttactgtatc tccatgtttt ggatatatta cacaaccagc
     6061 agaaattgtt atatttaatc catattttct ccatagttga aggtgtataa tcatattctg
     6121 tatttgatta tatagagtta gaatttcatt ttcttcaaca ttatcaacaa gaatgcccat
     6181 ttcgtcccca tcaagtttat aaagttcagc attatctggt aaaatagatt gtacagactg
     6241 tgctagtgtt tttattatat tatctccaaa atccctatca tacatctcat taacattttt
     6301 aaaatcgtca atatctaata atactatgca taatttttca atcataggat ttgaaatttt
     6361 atcttcaaat acactcataa attcatgata attcagtaac tgtgtcaatg aatcaatctt
     6421 attttgttta cctaattgcg tcattattcc tgcaaaaata cttggctctc caaattcatc
     6481 acgcattagt tgacctctac atcttaacca tatatattct ccactacgat ttttagccct
     6541 aaattccact gtatgataat ccatctggtt tttacctatt tcagtgtttg acttataaaa
     6601 acgattccag tcttctggat gtacaatttt tttccagtaa acaagcggat ttttaacaat
     6661 ttctcctggt aagtcaaata attcaacttg tgatggtgaa tatcgaaata cgcctgtttt
     6721 catattgcaa atgtatatat attcatctgt acctctaatc aaagcatcgt aaagcaatgt
     6781 agaattataa tcaaaattgt ctcttgaaaa attaaaaact cctttttctt ctttattatt
     6841 tgatatttca tgaaattcat taatcttaat tggtttattt aagcttgttg agtttgcaat
     6901 atctattgat tgatgcatat gaacaactgt gccatcttgc catgtaatta aactatcata
     6961 attttcaaaa acacgattta acttattaca tttttcatac cactttatta atactccttt
     7021 tttatcattc tttaataatt ctaaaacttt acaaaaacta caagtagaat ttttttcagg
     7081 atataatact tgccaacaaa cttttccttc tggatctaaa atattatatt cttctttcat
     7141 ttttttgttc ataaaaataa tttcattagt atgaatattt gtaacatata tattaatctg
     7201 tagttgattt aatataactt caaaattatg tttgttcata tacttatctc ctccatagtt
     7261 actgctcttt ataacaacat tgttaaaatt attcttttta gaagatttac ttataactta
     7321 tacatataca ctaaatacct taatttaatt agaaagttta ttacttcata ttttaaatta
     7381 taattgataa aaaaaaatac agcaatatag tattaccaat ttaaaaaaaa ttaatattac
     7441 ataatacatc tctctcttat attaaatttt aacttggtac taatcttgac aaattgtcca
     7501 caaaaataaa ttatatattt tattattgtt ttaaattttt ataaaaaatc agtattattg
     7561 atactattga agttaaaaag cattaatttc taaaaacatc ataatttttc taatagactt
     7621 aatcactttt aatatatata gtaaaacaaa aaacttatat tttataaata tcataatttt
     7681 tttactgata ttttattata taaattttat agaattaatt gtcaattttt tatgaaaatg
     7741 gtaagatatt tatggatggt atcttgttat aagaactata ctttaaatgt ttttaattat
     7801 tttgtcttat gtaactcata tcctcaggaa tgagattaga aattaagatg ttgtatcaca
     7861 aagtggaggt gatactatta aaataggctt tattggttct ggaaaagttg gaacatcttt
     7921 ggcaaattat tttttatcaa aaggttattg tgtttcaggc ttttatggaa ggaatcaatt
     7981 atctttatta gaatcaacaa atttaacaaa aacaaagatt tacagcaatt tgaaagatat
     8041 aatttatgaa aacgatatat tatttattac aacatcagat gattctattg aaattataga
     8101 caaaaaactt tccaaattta atttaaaaca taaatacatt tgccacacaa gtggctcttt
     8161 aaaatctagt atattgttct gttcaaaaaa agcaggtgca ttaatttatt ctatccatcc
     8221 tatatttgca ttttccaata aaaatactga cataaaaaaa atgaaagaca tttgtttttc
     8281 catagaaggt gataatgaac aagatgattt agttattcaa aatttcatag atgatttggg
     8341 aaaccaattt tttataagag ataaggatac ttcatccact tatcatttag ctaatgtttt
     8401 agtttcaaat ttagtattat ctttactaga tataggagta agttacttta ttaaattagg
     8461 tttatctgaa gaggaatctt taaaagctat cagtccttta gtaaaaaaaa acatagaaaa
     8521 tatacttgat aatggcttta ctaaagctct tactggtcct gtttctcgtg gagatataac
     8581 accaataagg aaacatctat ctgtattgga taaaaaagat gaggatattt acaaaatact
     8641 atccttaaac ctactaaaaa taattgcctt aggaaatgac aattcattaa aaggtataaa
     8701 aaatattact atagaaaatg caatcgaaaa tttaataagt aaatctgaaa aatacaaaga
     8761 aatttacaaa cttttaggag gaaaaaacga tgaaaaatac catacagact tttaagaatg
     8821 ctaaatatga aggaaaaaaa ctatctatgc ttactgctta tgactactca attgcaaaaa
     8881 taatggatga gtgtgatata aatggtattt taataggaga ttcattagga atggtcataa
     8941 aaggtgaaga aaacactcta tctgttacca tagacgaaat tatatatcat acaaaagctg
     9001 taaaaaatgg cgtaaaaaat gccttaatcg taagtgatat gccttttcta tcttaccatg
     9061 tttctataga agatgcagtt aaaaacgctg gtagacttat aaaagaagga ggagctcatg
     9121 ctgtaaagtt agaaggtggc tcaaacgtta taaagcaaat agaaagcatt gtaaatgctc
     9181 aaatacctgt aatggggcat ttaggattaa ctcctcaatc agtaaattca tttggtgggt
     9241 ttaaggttca aggaaatacc agtgaaacag caagacaact tattgaagat gctaaattaa
     9301 tagaaaaagc aggtgcattc tctattgtcc ttgaaggagt gcctacgaaa atagctgaga
     9361 tggtaactaa ttctatttca attcctacaa taggtatagg ggcaggaatt aactgtgatg
     9421 gacaaatttt agtttatcaa gatatgttgg gaatgtttgg agattttgtt cctaagtttg
     9481 taaagcagta tgcaaatata ggagatataa taaaagattc aattaaaaat tacatcctag
     9541 aagttaatac aggtgcattt ccacaagaaa aacacagctt ttcaataaat gaatctgagt
     9601 tagaaaaatt atactaatat taaggatggt acaaaatgct tgtaaaagaa attaaattac
     9661 taagaaatat aatcaaagat tggagaaaac atggctattc tataggcctt gttacaacaa
     9721 tgggattttt acatgaagga caccaaagtc ttataaaaaa agctgtaaaa gaaaatgata
     9781 aagtagtagt gagtatattt gtaaatccaa ctcaatttgg accaaatgaa gattttaata
     9841 gctatccaag agatatagat aaagatttta aatattgtat ggatagtgga gcaacagtag
     9901 tctttaaccc atcaccagaa gaaatgtatt taaaaggtaa ttgtactacc attaacgttt
     9961 ctggacttac agattttctt tgtggagcta aaagacctgt tcattttgga ggtgtctgcc
    10021 tagttgtttc aaagtttcta aatatagtaa cacctgataa agcttatttt ggagagaagg
    10081 atgcccaaca attagctgta attaaaagaa tggtcaagga tttaaacata gatacagaaa
    10141 taataggctg tcctataatt cgtgaaaatg atggattagc aaaaagttcg agaaatacat
    10201 atctctctga ggaagaacga aaatctgctc taatattaaa taagagctta agtttagcaa
    10261 aagaagaatt agtaaaaggc aatctaaatc cagagaatat aaaagaatta ataacagcta
    10321 aaataaattc tgaacactta gcaaaaatag actatgttga aattgtagat agtgagacat
    10381 tacaacctgt taagcaaata gaacattcta tacttgtggc aattgctgtg tttataggaa
    10441 aaaccagact aattgataat tttacatttg agttaaatat atagtctata attttatata
    10501 atatatctaa aaaataatag aatacctaaa aagtaataaa ttacctaaaa aataataaat
    10561 tgcttagaaa ataatagatt acaataacta aaattttaaa attaaattcc ttaaaagtat
    10621 gattaattat aattatataa gtatattctt attacactta tattaattta tattaaatat
    10681 ctactaactc aaatattcat aattaaactt taaactggat aaattttctt ttaagaatga
    10741 aagtttatcc agttttgcga ttataataac cagttttaca tatccacttg taaaatatat
    10801 ctaagcaata tatcatacta tatagattta tgagtgaaat aatatctgct atttactgaa
    10861 tatttttatt tttcgttttt tagggggatt agttgtgttt aaagataaga ttgatgaatg
    10921 tgttcatata atgactgcat atattgctag tttaaaagaa tactattcat tcatagaaac
    10981 tcaaattggt gattttatta aaaaatatgg agaagatgtt gtagagttat gtctccatag
    11041 agtgatgatt ctactatgcg aatgtggttt ggcataaaat taaatttatt aaaatgggta
    11101 agaagaatcc tatataatat tcttcttacc cattttaata tatcaatttc atagcttatc
    11161 gtttaaaata ttttacatcc attactagac aactttacat tctcttttta attctagtat
    11221 atttaaatca ttttagttgc tccttattta ttcttattac ttgttttatt tataaaataa
    11281 ttctttttaa taatgttttt tgttgatatt cctatcacac atccaattat ttatcattgt
    11341 cttgaaattg tttgcatact taatttaatc caattgaaac accccagcat agaatcccct
    11401 gtaaaataga agttggatta aatcctaaca tctatacaga aaatactact ccaagcacaa
    11461 gcaatataat ggaatatatt tatcacttaa ttttttatac tttttaaatc ccatacctaa
    11521 aacattaagt gcagctatta gaattaataa ttgttgtggt ataaaattat gcttgcttca
    11581 tatttattca ttttttgcta taaaagttct tgttttacaa aaaacatttg ttttgtatca
    11641 aaataatact tataaattac ataattctca taaaaatttc tagtattact tgtactctta
    11701 ataaataata gccaacaagt accttaaatc attatatcta tatctaataa gaaacacagt
    11761 aagataatct tttcgcccat aacttaataa aaactgttga tattagtagc aattgaattt
    11821 agttaattta tttataatat acataaattt aaatattacg aataaagtat tataaatagg
    11881 atactttcta aggggaggaa attatgatag ataatcaaaa atatgttatt ttatcactag
    11941 aattacattt atttttttca agaattatga aagagcatgc tcttttttta gaagcaggat
    12001 tcacaaataa aaattataat cttgctatgg aagctgacca ctataaaaag caatttgaag
    12061 atttattatc atacactgtt agtgctagta atggtataat tagacctgat atattatatt
    12121 cagaagagct tgtaactact ctcacatcag ttgcagaaca aaaaacagaa gagtttacag
    12181 ggatagaaat aaacaaaaac atcactacaa gagaattaaa tctacaaagt ggtgtaaacc
    12241 cacaagttgg tcaagactta gtgaactatg tagctcaact taactctgat gcaataagat
    12301 tacttgatgg gcttattaat tttaaagaaa gagtcttaga tggtgtacta tcatgtacta
    12361 tatttacatc aaactaccct ctacttcttg aacatataat acatgaagca aatttatatc
    12421 gttcttatgt agttgacctt gaaaataaaa tagatattga gtcaaaaaac gctaaagaaa
    12481 tagaattatt ctgggaccat attatgatgg aacatgctct gtttatgaga ggattactag
    12541 acccctcaga aggtgaacta ataaatactt caaatgattt tgctataaaa tttaatgaat
    12601 taattgaaaa aacaaacgaa atgactgatt ctaatatcaa gaacattaca gaagaaactc
    12661 taaatgaaac tgttgagttt aaagatttta aagaagcagg agcatcagga atagaacagt
    12721 gtaagataaa atctataata ttaccacttt tagcagacca tgttttaaga gaggcaaatc
    12781 attatattag aatattggag agttataaaa acatgtaatt aaaaattact tttaaaataa
    12841 tctttgcata tttagataaa ataaaggtac agttaactgt acctttattt tttataaact
    12901 tataaaattt aaacaagtta ttcataaaat aaaataataa tcatctataa cccacaactt
    12961 tattttatat taaataaaaa gtattagtgg ttatgtttta taagtatttc tttattcagt
    13021 tatttattaa aaactaatag taaatcttat actaatcgca tatttatgtt ataactatat
    13081 tgtaactatt ttcgtaatct taggaaaaga ttacttataa aattaacctt atacaataat
    13141 atatcgtata atcttaatta gcataatagt tacaatatta aaatttaaat atgggagtga
    13201 ttttagtatg ataagacaaa caccattaga gaaacgatat gacaagctag gtcctcatat
    13261 tgtaacagca ctcaaaaaac gttattttga tgcttattac tgtaaaacta gaaatgaagc
    13321 tttgcaacaa attttagatt taattcctca aaatcatgta gtatcatggg gaggatctga
    13381 aacacttaaa gaaatgggcg tacaaactgc tgttagagag aaaggattta aagttattga
    13441 tagagattta gcaaaaactc cagaagaaag aactgaaatt atgcgtcaag cacttctatg
    13501 cgatactttt ttgatgagta gcaatgcaat tagtgaagat ggacaactct ttaatattga
    13561 tggaaatggc aatcgtgtag ctgcaatgat atttggtcca aaaaatgtta tagttgtagc
    13621 tggtatgaat aaaattgtaa aaaacattga tgatgcaata caaagaacta gaacaattgc
    13681 atctccagca gttgttcagc gttttcaaga tgtcaataca ccatgctata ttaatggaag
    13741 ttgtatagat tgcacaagtc ctgaaagcat ttgtgcatac atggttacta caagaatcag
    13801 tcgtccagca aaaaaaataa aggtaatatt ggtaggagaa aatcttggtc tataaaatat
    13861 acatacatgt aaatagctct ataaataata aaatcatatg aaataactta tttctaaaag
    13921 tggtagaata aaagcttcta caagactttc attctgccac ttttatattc ttttaatttg
    13981 tgtttctata ttattaattg ctccaatttt catatatatt actaactatt tttattttca
    14041 taattttttt gttcttcatc aagctgttta taataatctt tattatagtc agctagataa
    14101 tctataccac ctcctgtaat cacatttaat aatttcattg cagattcttg attaacttta
    14161 caaacataat tatcaccaga tttaacaagc tctaatgtaa tattaaattc ttttttcttt
    14221 gcagaatcaa tatctttcat agttggattt ggcatcattt ctcctagttt aggaggattc
    14281 ttttttaaaa tagaaaccat atcagtattg ttaattttta aatctacagt cactttatcc
    14341 ttattatttt ttatatctga aatttcccaa gtcatatttt tagaatacat tttaaatcct
    14401 tctttatctt cgtatataag attacctaac cctgattttg ggaaatactt atcaacagta
    14461 tctgcatctt gtgtttttat tgaattaaac atactatcca cttcattttt tatcttatta
    14521 tcattagtac aaccagctaa caccagtact gatattgcaa acattataat acatagaata
    14581 aatttcttca ttaaattata tccccctata cttttttgca caaatattat tctctttttt
    14641 atcttttgaa aaagttgtag taattgcatt ttgtggacaa acttttatac attcaccaca
    14701 cctaatacag tctggactat ttacatcttt atatattggt atatcaagct tacattttgt
    14761 ttgacatgct gtacaatttg tacatttatc tttatcaatt ttaaatctat atattgaaat
    14821 aggattaaaa aaaccataga ttgctcctaa agggcatata tacttgcaaa atggcctata
    14881 agtaatgatt gacatcaata atatcaataa caaaatactt aacttccagc taaataaaaa
    14941 tcctattgat tctcttaaat tctcatttcc taaaataagt ggtattcctc ccaaaagtgt
    15001 tcctgaaggg caaatccatt tacaaaacca aggatttcca ccccctgcta catttacaat
    15061 agcaactggc aaaataatta caaatattat taagactata tactttagat attttagata
    15121 tttatcacca taaacttttt ttatctttac tggaaagggt actttatgta gtaaatcttg
    15181 tacaagtcca aagggacaaa gccaaccaca aacaaatctg ccaaaaaaag caccaaatgc
    15241 cattaaaaaa ccaacaacat aaaatgagaa tttatactct ctgcttgata aaactgcttg
    15301 taatgaacct attggacatg ctccaagtgc acctggacat gaataacaat tcaatccagg
    15361 tacacataat tttttacttt ctcctccata tatagttcct tctaaaaatc catttacata
    15421 tccatttgtt aatgctgtaa atgcaacttg agtaataagt cttatattat tatttacttt
    15481 agataataac ttcattcctc ttctcctaac caataccaat acactcaaga caaatcataa
    15541 ttgctttagt taatactgta tttgtttctc cacgatatgt acctaatgca ataaatataa
    15601 tactaattgc aataatagaa atgccttttt tattatcttt aataaagtta ctcattggct
    15661 tttaccattt ttagtctttc atctataatt tttttccaat cttccttact atttgcacct
    15721 acaaccttct cacccacaaa gtttcctttc ttgtctacaa aataagttgt tggaaactcc
    15781 ataactcttt taaaatcagt ttttttaagt tcttcagata cagtcaattg ttggtaagtt
    15841 gcatctgact ttttcataat gtctttaact aaatttttct cttcatttga aagaccagtt
    15901 ctcatatcag ttttatcaac ttctacaact aatcccttta tagctacatt ggaattatta
    15961 ctctcatatt cttttgataa tgcttcaagc tctggcattt cacccacaca tggtccacac
    16021 caagtagtcc agacattaat aagagtaagt tctttatttg aaaatatctc ttttgttacc
    16081 ttatttccat caacatcctc cgtatctaaa ttactaaacc attcactatt attcttgttt
    16141 ttttctactg gcttagattc ttttttgcta catccagaaa tcatacctaa aacacaaata
    16201 catcctaaaa ctactatgaa aaaccttttc atatctcaca ctcctagaat ttatatagta
    16261 tataaaatcg ctgcttgaaa taaaaataac ttatcttcta tattaaagta attatattta
    16321 ataaataaga gctaatttaa aaaaagatat acagttaaaa tctatttctt ttcagacaaa
    16381 atcttatata tatataatag cttgtaaatc ttaagattat atacatatat ttctaaagat
    16441 tttcttaaga aacagttaga ttttactaat ataagtttat taattagcat tatactaatt
    16501 tatcttaata tgattttttg ttgattttaa gctgtttatc gtataaataa aatttttctt
    16561 gactatatag ttactatata gcttattata tatagagagt aataaaagga ggtaaaattt
    16621 atggaaaatt tatttacaag aaaattcact acttttgaat ttctaaaatt tgtttctcct
    16681 gcaattatat ccatgatatt tatatctttg tacacaataa tagatggcat ctttgtatcg
    16741 acattagttg gttctgatgc tcttgctagt ataaatattg tactacctat aattaacctt
    16801 gtttgtggat ttggaataat gatggcaact ggtggaggtg ctatcgtttc tatacgtatg
    16861 ggtgaaaata gacaggatga agccaactct acattttctt ttatagtttt gttttcattg
    16921 attgttggga ttttattcac agtaatctca tatttcttta tcaaagaaat atctattttg
    16981 cttggtgcaa cagataagtt attaccatat tgtataactt atggtaaagt tatgatttta
    17041 tgtacaccat tttatatttt aaaatttata tttgagtact ttgcaagaac tgatggaaat
    17101 tctaaattta gtttatttct atcagtcatt ggtggtgtaa caaatataat attggattat
    17161 gtatttatta aatattttgg aatgggtctt ttaggagctg cagttgcaac tgctataggt
    17221 attattttaa cttgtgtttt aggtattatt tacttcttat ctaataaatc tacactaaaa
    17281 ttaagaaaac caaaaaccga ttttagactt ataagagata ctatgataaa tggttcttct
    17341 gaaatggtta cagaattatc tacaggaatt acaacattct tatttaatgt agtagcttta
    17401 aaattagcag gagaaaatgg acttgctgct cttactatag tattgtatgc tcatttttta
    17461 atgacatcag tctatctagg attcgctgct ggagtgtctc cattaataag ctataatttt
    17521 ggtgctgaaa acagtgataa attaaaagaa acatttaaac attctctaaa atttatattt
    17581 gtttcttctc ttttagtgtt tatttttgct ttagtatttg caccatttat tgttagggtc
    17641 tttgtaagtc cagataacac agtatttaaa ctagccttac aaggattaaa aatatttgca
    17701 tttgcttttt tgtttgttgg tataaatata tttgcatcag gattttttac agcatttcac
    17761 aatggaaaaa tttcagctat tatatctttt agtcgtgcct ttgtttttat aatcatagga
    17821 atcataattc ttcctcctat gttaaacatg actggattat ggcttacagt tccatttgct
    17881 gaggttataa ccatatttat atctattcta tttataaaaa aatataaatg tagatataag
    17941 tattaaaaat taatacttaa aatcaacatt tattaaaact aataaacctg ctttaaaata
    18001 caaatttaca aatttgattt ttaagcaggt tttattttag ttataataag tcatttgcat
    18061 actctttaat tggtgctttt ctaagtaata aaattataaa tattatgcaa ataactataa
    18121 ttcctacttt tgttccaaat aaaataaaag gattctgaaa tgaataaata attttttcta
    18181 aatacaatag cattttatgc atatttttag ttgcaaaatt aactatataa attatcatta
    18241 atatcggtaa tcctatcaat atagtaatac tagtaacttt tctaactcta tatgtaaaag
    18301 ctccaagtaa cactcctata aaacctatac atatttcatt tatacatatt tgtacaaaat
    18361 aatttaaata agttagtggc atacttgatg ttgaaggatc tatcagtgct gatatagatg
    18421 tccaaatcat atctctcttt agtaaaactg atagttctat actgtaacct gttataattt
    18481 ctataaataa cttcgataaa aaaatcaaaa ctatacctaa aatagaaatc acaaagctta
    18541 aaataattaa atctatgaca atagctttta tacaactttt tctatctgct cttatactta
    18601 aagctcctga aaagtcttta tttgctatat ttactccata cacaaatagc agtatagtta
    18661 tatatgttaa aataggattc acaatcgtgg ataaattagt tttagatgct tctccaaaaa
    18721 tcttgagaat aaacactggc aaaatattca taacaattcc cacaatcata aatataatta
    18781 tatacaattt agtattttta ttaaaaaatt ttatatatgg ctttaattca ttcaattaca
    18841 attcctcctt cttagtcatg ttaacaaaca tatcttgtag ccctatgtat cctacatcaa
    18901 tatttgaatt tttaagtatt ttttcatcac tttcactaaa atcaccatag taaaaataag
    18961 caactgcatt tccaaatgcc tttttaggtt ttatattttt tatacattct aatttttcta
    19021 actcttcttt atttccagta atataatgag ctttttgttt tatgacatca atttcttcat
    19081 ctataataat ttttccctca tttaatatta ttacatgctc cagtaaatca tctatttcat
    19141 caatcaaatg agttgatatt attattgtcc ttggattttt tatataacta tctaaaatta
    19201 tgttataaaa ctcttgtcta tttactgcat ccagaccaat tgttggctca tcaaatatgg
    19261 tgatagctga attagaacaa atacctatta tatttgaaag tatagttttc atacctcttg
    19321 acagttgttt atactttttt ttagtattta aatcaaaata tttgcataat tcttcttcta
    19381 agcctttatc ataactttta taaaaactag aagaaaattc aaatatctga cctactttaa
    19441 aatctggact ataaaattct ttttccctaa cgatacaaac ttcttccaaa acttttatat
    19501 cttcttttgg gttctttcct aatatttcta tctcaccttc attttgaatt aactgattta
    19561 ccattatatt taataatgtt gtttttccag ctccattctt acctaataaa ccatatatct
    19621 tatttttttc aaagcttaga gacatattat taaaaatatt ttgcttctta aaactgtgag
    19681 ataaattttc tatcttaata gaactactca tatattaatc ctccttgaaa ttaattataa
    19741 tatcaaccaa ttcttctcta tttatttcta atttgttagc ttcttgaagt aggtttttta
    19801 caaaattatg tttaaaattt tcttttctag cttcttttat aatagttttt gcaccatctg
    19861 atacaaacat ccctatcccc ctcttcttat ataaaatatt tttatcaacc aatatattta
    19921 taccttttaa tactgtagct ggattaattt tataaagctt tgaaagctct gttgttgatg
    19981 gaacctgttc ttcttctttt attccatttg atagtatctc atcttcaatt gctcgtgcta
    20041 tctgaataaa tataggttct tcattattta atactaattt cataggttcc tcctttctcc
    20101 atcagttagt tactcaacta attaactata taacttataa tatcttgaaa aatattttct
    20161 gtcaatacta aataaaaaac agagggaaaa ttccctctgt tttttgttct ttatatttat
    20221 aattaaattt tgatttttgt aatcctatcc cataagttaa aaactttaat aatctgttgt
    20281 atcttcattt tttaatattt tacatattga gctagttcct aacctttctg ctcctgcctc
    20341 tataaatttt tctgcatcag aaattgattt aactccccct gcagctttta tttttacatt
    20401 ttttccaaca tgctctttca taagttttat atcttctaaa gtagctccac ctgttcccat
    20461 tccagtagat gtttttataa aatctgaacc tgacattgtt actatttcac acatttttat
    20521 tttttcatct tcatctaaat aacatgtctc tataatgact tttaatactt tatctcctat
    20581 agcttttttt atttctttta tttcttttcc tatattatca taatctttat tttttatatc
    20641 tgaaatgttt acaaccatat caacttcatc tgctccattt tcaatagcat cttttgcttc
    20701 aaatactttt gtagcagtag tttgatatcc caaagggaac cctatcactg tacatatctt
    20761 tattttacct tttagatatt ctgatgctct tttcacatat gatggtggta tgcaaactga
    20821 tgctacactc atatctacag cttcatcaca taaaatttta atatcttccc atgtagttgt
    20881 agcttttaaa atagtatggt ctactgtttt taatatatgt ttcataaaat cctcctaaat
    20941 ttataattaa tataattaga ttactttttt aaatgcaatt ttctctttgc aatgtttagt
    21001 atcatatcaa cctcttcaac tttaaaaata atcattagta gtgtataaat tccacctcca
    21061 actataactg aaatagctag tgatacaaac tcattaaatg ttcctactcc caaaattcca
    21121 aatatgaatt tatacgtaaa gtatgataaa acacccataa ttaaagatgc aactaccgat
    21181 ttcaaagttg cttttattat tttatcttgt ccaaaatatc caacttttct ctttaggttc
    21241 aagaagagta acaatataca tgcaattgat gatgaactag ttgcaagagc aagaccacca
    21301 tgagccattg gttttattaa aactaagtcc aatactatat ttacccctac agatataatc
    21361 ccatttacca taggtgtttt tgtgtcttgt aatgaataaa aaacctttcc caaaatatct
    21421 cttaagccaa atgcagtcat accaactgca taaaaaatta aggcagttgc tgtcatttgg
    21481 gttgccctcg catcaaaagc acctctctca aaaatgattc taacaacagg agttgcaaaa
    21541 aaaatagaag caactgaaat aggaatcata gaaattatta tcatatttat actggattta
    21601 actgaactag taaacttctt ttgattattt tctgcactta acttagataa cataggatac
    21661 ataacagata ctattgaagc tgtaaatgtc cctgtaacaa aaccatttaa tctatctgca
    21721 taagtaagtg ctggaatgct tcctttaact aatgttgagg ctaaagttgt atctaccaat
    21781 gagttcactt gattaacagc aacacctata aatactggtg aaagtaatgc tagtaattta
    21841 ataaggctat catctttaaa gtttaagtag tataagtatt tgtagttcgt ttttttaaca
    21901 aaaaacatgt aaaagagcag ttgaactacc atagcaacca cagcaccaat tggaagtatg
    21961 tatggtccaa atatggtact taacattatt gaaataatta ttactatatt atagggtata
    22021 cttccaaatc caactacaat aaagttctct ttaatttgta aaaatgctga cataacactc
    22081 gtaataccta tgaatattat tcctg
//
LOCUS       DAYAKB010000058        21986 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.058, whole genome shotgun sequence.
ACCESSION   DAYAKB010000058 DAYAKB010000000
VERSION     DAYAKB010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.058"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(226..1170)
                     /locus_tag="ACGI3L_002649"
     CDS             complement(226..1170)
                     /locus_tag="ACGI3L_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9198347.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            1488..2918
                     /locus_tag="ACGI3L_002650"
     CDS             1488..2918
                     /locus_tag="ACGI3L_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198348.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            3118..3702
                     /locus_tag="ACGI3L_002651"
     CDS             3118..3702
                     /locus_tag="ACGI3L_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HFG9198349.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(3806..4585)
                     /locus_tag="ACGI3L_002652"
     CDS             complement(3806..4585)
                     /locus_tag="ACGI3L_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9198350.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(4643..5899)
                     /locus_tag="ACGI3L_002653"
     CDS             complement(4643..5899)
                     /locus_tag="ACGI3L_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFG9198351.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGIAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            6157..7056
                     /locus_tag="ACGI3L_002654"
     CDS             6157..7056
                     /locus_tag="ACGI3L_002654"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFG9198352.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            7080..8528
                     /gene="ddlR"
                     /locus_tag="ACGI3L_002655"
     CDS             7080..8528
                     /gene="ddlR"
                     /locus_tag="ACGI3L_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HFG9198353.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            8611..9393
                     /locus_tag="ACGI3L_002656"
     CDS             8611..9393
                     /locus_tag="ACGI3L_002656"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9198354.1"
                     /translation="MSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSNPNKKGNIK
                     SQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPI
                     SFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKIKLIDDYD
                     AVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDVTPKVSTVY
                     ADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            9419..11338
                     /locus_tag="ACGI3L_002657"
     CDS             9419..11338
                     /locus_tag="ACGI3L_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9198355.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGFIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(11580..11927)
                     /locus_tag="ACGI3L_002658"
     CDS             complement(11580..11927)
                     /locus_tag="ACGI3L_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HFG9198356.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(11914..13842)
                     /locus_tag="ACGI3L_002659"
     CDS             complement(11914..13842)
                     /locus_tag="ACGI3L_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HFG9198357.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(14254..16443)
                     /locus_tag="ACGI3L_002660"
     CDS             complement(14254..16443)
                     /locus_tag="ACGI3L_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HFG9198358.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKFGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDIYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            16774..17505
                     /locus_tag="ACGI3L_002661"
     CDS             16774..17505
                     /locus_tag="ACGI3L_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFG9198359.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LTLNIELKTDKINYPNIEKGVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            17585..18220
                     /locus_tag="ACGI3L_002662"
     CDS             17585..18220
                     /locus_tag="ACGI3L_002662"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFG9198360.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(18471..19064)
                     /locus_tag="ACGI3L_002663"
     CDS             complement(18471..19064)
                     /locus_tag="ACGI3L_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HFG9198361.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(19135..19998)
                     /locus_tag="ACGI3L_002664"
     CDS             complement(19135..19998)
                     /locus_tag="ACGI3L_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HFG9198362.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            20161..21330
                     /locus_tag="ACGI3L_002665"
     CDS             20161..21330
                     /locus_tag="ACGI3L_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9198363.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNSNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            21431..21907
                     /locus_tag="ACGI3L_002666"
     CDS             21431..21907
                     /locus_tag="ACGI3L_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HFG9198364.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSIPKWCSHWPKSVEKSGEFNWEDEIEF"
BASE COUNT         8091 a         3305 c         2776 g         7814 t
ORIGIN      
        1 ctatagttat ttagtattta caaaacaaaa tattaatttg tacatttata caatatataa
       61 taaaaaatag atagtctaaa ctgtatctac ttatatttta tttgtactgt ccactttatt
      121 ctataaaatt tataaatagt tattttttaa taccaaatat aatttggtat aatttttgtt
      181 ggaatctaca atgtatacca ataaatcctt tttaagtata taattctaaa tactttcagt
      241 tttttcaatc tgctttaact tgttggactt ataaaatatt cttatttcat cataagaaag
      301 attaagtgct actactgcag atattaacat caacatcact ccaaataact tccctaagga
      361 aaaactttct cctaatatag tgcaaccaat tattactgaa ccaactaatt ctactgatgc
      421 cacaacacct gcaactgaca actctacacc tttagatata cctgctgcat aaaaaatata
      481 tgcaagtgca gctggaacaa tgcctaacat tagcatacaa gataaaacat ctaaatcctt
      541 agcataattt aagatttccc aaggtcttga agaaggaatc ataaatatag ctccaaataa
      601 gaaactgtat actaatattg ttgaacttga aaattccttt aaagcatttt tactaatagt
      661 tggcataagt gcatatgcta ttgctgataa tactccaagt aaaagcccaa aagcgtttaa
      721 accttgaaaa tccaaacgtc caccagtcac tgccataatt gcaccaataa aacaaagaat
      781 aagtgaaaat aatttgcttc tagtaatatt ttctttataa cataattttg aaaatattgc
      841 taaaaacagt ggtgatgtat atagtaaaac tgctgcaatt gatacacccg caatgtcaat
      901 tgctttaaaa taacataaat taaacattgc ctgacatata attcctatta ttactgaata
      961 tataattcct tttttgttta tctttaagat ttgtggtgtc cttatagatg aatatacgcc
     1021 taaaactata aatccaaaaa acaatcttgt aaatgctact tgttctgatg tcagtccatt
     1081 tcccattaaa aactttccaa ataatccaag tgtagcccat aataaccctg ctattgctat
     1141 aaatacatac cctttacttt tttctcccat tttaaattcc cttctatttt tatttagtca
     1201 atttacactc ttctttttaa gcaaaaacta tgccatctta aatcaatata tatcgactct
     1261 aaaaccctag tctttccaat aatactaata aattttcaat ttttttatat ttatttttcg
     1321 cttactttaa gttgatttag acttatttta attgtaaaat gagttatata taacttattt
     1381 aaagttaaaa tagactgaaa cttatatata aatatcaaat tttaagtata ttaatcaatt
     1441 aaacctattt taatatatca ttaaaaattt aggaggaaaa tataaaaatg aatttagatt
     1501 tggaatttta tcaaaaaata ttagaagctt cccatgatga aatatgtgtt tctgatgata
     1561 aaggaataat aatatattgt aataaagcat ttgaagaaaa ttatggtcta aaaaaagaag
     1621 atattttggg aaaaaatgtt tcttttttag aagactctgg atattcaaca aaaagcccca
     1681 taccaattgt attaaaaaca aagactaaat tttcactgga acaagatact caaacaggga
     1741 aaaagcttat cataactgct acccctatat ttgatgaaaa tggacactta gaatttactg
     1801 ttgaaaattg tagagatata actgaactta ataatataaa aaataaactt gaagacacaa
     1861 aaaagcaagt aaaaaaatat aaatctgaag tagaaacact atacagaact gcacttagaa
     1921 ttgaagatac tgtaattatg gacggaatag ttatgagacc aatcataaac acagtaaatc
     1981 atgtttctaa aacggatgta agtgtacttt tattgggtga atctggaaca ggaaaaagct
     2041 cacttgctag atatatacac cacaacagca atagatctaa tggcccattt ataacaataa
     2101 attgtgcaac tatatctcca caacttcttg aatctgaact ttttggatat acttcaggtg
     2161 cttttacagg tgcaagtact aaaggtaaag ttgggctcgt agaattagct aatggaggaa
     2221 ctcttttttt agatgaaata ggagatatac cacaaaatct acaggcaaaa tttttgcaat
     2281 taatacagga tagaactttt actccagttg ggagcttaaa aaataaaaag gtcgatataa
     2341 gaattatatc tgctacaaat gttgatttag tttcaaaagt aaaagaaaaa aagtttagag
     2401 aagatttata ctatagatta aatgttatag aaataaaatt gcctcctctt agagaaagaa
     2461 gggataatct agtggaaatt ataaaatatt attttaatag gtactcaagt gacttcaacc
     2521 taaataaaac tatttctaag gaagctatgg atgctattgc aaattataga ttcccaggca
     2581 atataagaga attacaaaat ataattcaaa aaatcttgct tacttgtaca gataatcata
     2641 taacaataga tgacttacca aacattctta caaaaaatat acatattacc aataatggaa
     2701 ataaaacaca tatatcccaa attaataagg ttattatatc tgactcaaaa tctactaatt
     2761 ataaaaataa aaattttgac actttaatta aagagtatga aaaaaatata attttggatg
     2821 cttatgaaaa atttggtagt tcttataaag tagccaaaca ccttgaaatc tcacagtcta
     2881 aagccaatag gttaattaga aagtatacta atacttaatt ttaaatttga taaataaaaa
     2941 cttaacacta tttacatatt gtaaatttgg ccatttactg ttattatgaa tatggttgaa
     3001 attatttaaa taaatactgt tgacttagtt tcatatattt accattaaac ttttatcata
     3061 aatatcatat cataataata tatttaataa gtctaataaa ctatacgagg tgtaaatatg
     3121 ttaatgaata cccattttat tatggcaaaa tcaatacttg ataatataga tgaaaataaa
     3181 acattcttta taagcgaaaa aaattttata tatggcaata taaagcctga tgctttttct
     3241 aaatataaat taaaaaaaca ttatttagat gagtcattta atatgattgt ttctaaaata
     3301 aactatctat gcagtcttaa tatagatagt ctttctaaat acttttcagt aagtagactt
     3361 agtcaggaac taggagtcat atgtcatttt ttatgtgatt ttttctgtgt agctcacagt
     3421 gaacgttggg aatttaagca tagcttaaat aaacatgtta cttatgaaag agaacttgga
     3481 gcatttgcaa aagatgttga tttatctaaa attaaatgtg gtactataaa tagtagtttt
     3541 gagaagtttt ttactaaact ttatagtgat tacaaaaaga aaactgatta tatgaatgat
     3601 ttaaaatttt cagcttatac ttgtaatagt gtcataaatt atatacttga ctctatttta
     3661 tctaatacaa taaaatcata tcatatagca aattgcggtt aacttaagaa tttttaaact
     3721 tatataaact tataattgaa tataattaaa atgactgctc tatagaatat aattttatac
     3781 ttctctagga cagtcatttt ttatactaac tatttatctc cattataaca tctatggcac
     3841 tttttacact atctactaca taatttgcac tttgctttac atcttccctt gccttagaca
     3901 ttgcaaaact atatttaaat ccttctaaca tgcaaatatc atttggagaa tccccaatag
     3961 tagcaacttc atctggactt acatttaacg tttttattac atgctctata cttcctcttt
     4021 ttgacacact tttaggaact atatttaaag tatatgttcc agaaaaatat atttctaaga
     4081 cttcactaaa ctcacttttt agataaagtt ctattctgga taactcttcc aaattttcag
     4141 aacatacgcc tatatttcct ataagattat caaaactact tcttttttca aaatctgggt
     4201 caactataaa gtcactagaa taatgtctaa aagcagtggt atcactaccc acaattacat
     4261 cacccttata tttaaaataa agttgtgcat cacttgactc aaatctatca atgacttttt
     4321 ttactaaatt atcatctatc gttcttttaa aaattacatt ataatcttta tcatatataa
     4381 atgaaccatt ttcacataca tagtatccat tcatatctaa actatctttg ataatattat
     4441 gtgcttgttt aaaaattcta cctgtagcaa cattaaactg tactcccttt ttttctattt
     4501 cttcaattgc tactatatct tcttttgtta tggttccatt ttcatataga gttccatcta
     4561 aatcacaaaa tatatgtttt atcataaatt aaaagcctcc aaaaacaatt ttatatttta
     4621 ctaatacttt aatcaaaata acttaaagct tttctaattg tattctcaat tcattaagca
     4681 aatctctagt agctcttaat cttatctttc ttctatcccc attaaatata tttttcttta
     4741 ctattgtttt tccatttata tatattgcag tataaaccag tcccacaggc ttctctttgg
     4801 ttcctccacc aggtccagct actccagttg tagatatacc tatattagct ttaagtcctt
     4861 tagcaatgcc ctcagccatt tctatagctg tttgctcact tactgctcca aactcttcca
     4921 aagtttctct ttttactcct aatcttttca ttttagaatc attagaatat gttacacaac
     4981 cttcaagaaa tacagaggat atacctggat agtttataag agatgaagaa accaaacctc
     5041 cagtacaaga ttcagccact gctattgtta gatttttttc tacaagtagc ttagaaacag
     5101 catcttctaa agcagtctcc ccttcagata tggaaatatc tccttcagta tatacatatt
     5161 taccaactct actttttatt ttttcttcta ctggttttat taatttaaaa gcttctcttt
     5221 cattttcagc ctttgcagtt attcttattg taacttctaa ttcttttgca tataaagcaa
     5281 ctgttggatt agtctgctca ttaattatat cgagaatttc taattctaga tttgactcac
     5341 ctattccata taatcttaaa gtcttagata ctagcatttc atttgtgaat tgttgtaagt
     5401 aaggtttgac actctcatta aacatagctt tcatttctct tggaggtcca ggcaatacta
     5461 ttataaattt accatctttt tttaaaattg cccctggagc tgtaccatta ttatttttta
     5521 gtactatagc atcttttgga aagtacactt gtttcatatt attttcggcc atttttttcc
     5581 ctgttttaac aaagaaagat tccaaaacct ctagtgaagg tttatgtagt tctaatttct
     5641 gaccaaagta ttctgcagca gtttcttttg tcatatcatc accagttggc ccaagaccac
     5701 ctgtagtaat tacaaaatca cttctcttta agctttcatc aaaacattct aaaagtcttt
     5761 gtttgttatc tccaacagta ctctgatggt atacttctat tcccaatgat gcaagttctt
     5821 tagctaaaaa ttgagaattt gtatttacta tatctcccaa taatatttct gttcctacac
     5881 ttattatttc agctttcaaa atttatcact ccttgattta tagccattaa gactagtctt
     5941 aagttcataa caataatttt agcaaaaata ataacataaa taaagttaaa aaatcattta
     6001 aacatatctt taaactagat tattattcta aaaccacaca taatataaac ttcgtatata
     6061 gtggtacttt catcctcaac tgttaattca tataattaag tatgtaaata aaaagtttac
     6121 tttaaaataa taaaaattaa aataggagtg tataatatga aaatagcagt tataatgggt
     6181 ggaatatcat cagagagaga agtttcttta aattcaggaa aagagatata taataacctt
     6241 gataaaaata aatatgaagt tgtaaaggta ataatagatg ataaaaaaga tatatttaca
     6301 aagataccag aagatataga ttttgcaata cttgctttac atggaaaatt tggtgaagat
     6361 ggatgtatac aatcaatact tgagactatg gatataccat actctggatg tggacctctt
     6421 tgcagtggga tgtgtatgga taaaaatata actaaaaaaa tgcttagaga ttcaaaccta
     6481 cctactgctc catgggtttt agtaaaatca gttgatgaaa tagactatga tgaaatagat
     6541 aatataggtt atccagtatt tataaaacca aactcaggag gttcaagtgt agccacattc
     6601 tttattcatt ctaaggatga agttgaagaa gcagttagaa aaggtctgga agttgatgaa
     6661 tttgtaatga ttgaaaaata tataccaggt ggagaatata cttcattcat attaaatgga
     6721 gaagtgttcc ctacaatatc tataaaatct gattcaggat tctttgatta tgaagctaaa
     6781 tactcagttg aaaaaggtgc aaaggaagaa gttgtttact tagatgaaga acttcaaaaa
     6841 agagtaaacg aaatttctga gacttgttgg aaaattttta attgcaaagc atatgtaaga
     6901 gttgatatga ttataagtga aggtattcca tatgttcttg aactaaatac tcttcctgga
     6961 atgactcaaa ctagtttaat tcctagaagt gctgctgcta gaggtattaa gtacagtgaa
     7021 ctattagata aacttataga atactcttta aattagatga aataatttga ggtggtaatt
     7081 tgatattttc aaatctaaaa ttaaatgata atgaaccaat ttatatacaa ctaaaaaatt
     7141 atataagtga tatgatatca aaaggactaa ttccagacaa tagtaagctc ccttctacaa
     7201 gggagcttag tcagctttta caagttagcc gaaattctgt agttttaact tatgaagaat
     7261 taaaatcaga aggattaatc tactctattt caggaaaagg tacatttgtt aaatcaaaga
     7321 ataagtcttc aaatactaca tggtcattaa actgggattg tttagagaat acatactcta
     7381 aaaaagccaa tgaattggac attataaaaa gtgaaattcc ttggagctct gacctgattt
     7441 cctttaaaag tatttctcca gatggagatt tattcgacat ggaagaatta aaaaaatcct
     7501 ttttaaatag aatttcacta gaaggacata aattactcaa ctatggatat gcacaaggtt
     7561 ataagccact tattgactat ttactagaat atatgacaaa caaaggtgct gatataagta
     7621 ataaagatat actaataaca aatggattca cagaaggctt tgatattatt atgtcatctt
     7681 ttacccaaga aaaagactac ataatatgtg aaaatcctac tcataatact gctataaaaa
     7741 ttatgaaatc tcataacctc aatatcttag gtgtagatat aaatgaagat ggtttggact
     7801 tcaatatgct agaagacaat ttagttaagt ataaaaataa aataaagttt gcatacatta
     7861 caccctctta tcacaatcct acaggaattg taatgactcc tgaaaatagg tacaaattct
     7921 ataatcttat gaaaaaatac aatatagcaa ttatagaaga tggatttaat gaagaattac
     7981 tctacaatag ttctcatata tttcctatct gttccctaga taatatgaat aatggggtcg
     8041 tatatattgg tagtttttca aaaattttat ttcctggaat gagaattgga tggatatttg
     8101 cagataaaaa agtaatcaat aagctagaaa gtgtaaaaag gtgcagaaac atacatgtat
     8161 cctttttaga ccaaggaatt ttatttgatt atttaagtaa tggaggtttt gaaaaataca
     8221 ttaaaaaaat acgtaaattc tatggagaca aatttaactt tgcatataaa tgtataaaaa
     8281 aatatataaa aacagaatat atcttgggtg atggtggttt gcatatattt ataaaactaa
     8341 aaaatataga tactagagtt ttattagaaa aatgttatga aaaaaatgtt atatttatgc
     8401 ctggagactt attttttaca gataactctg gttttgatac tttaaggctc ggattttcta
     8461 ggttgtcttt tgaagacatt gaaattggaa taaaaataat tggagaaact ataaatgaaa
     8521 tgttctaggt taactaaata ttgttagcct agtttatttt tatgaggtat aatatatata
     8581 gtttatatga atctaatact gggggataat atgagtaaaa agtcaaaacg aagaaaaatt
     8641 aataaattaa aattaacgat tgtaataact gtattatttc ttgctttatt atctatatat
     8701 gagatactgt tctctaatcc caacaaaaaa ggtaatataa agagtcaaga aactatgcaa
     8761 aataaaaata atacaacaga tgattctaaa aataatcaaa gctctaccaa aaagcaggaa
     8821 gataataata tcaaacctac tttttcatat tcttcaatac cagataatat aaaaaataaa
     8881 atgattggta aatctatgcc tactgatgaa cctataagct ttgatagtct atcttattta
     8941 aaacttacat attatggatt tgatgaaaaa actcatcaag gagaaatgat agtaaacagt
     9001 gaactagctc cagaagtagt ggatattttt aaggaattat acgaaaaaaa atatccaatt
     9061 gaaaaaatta agttaataga tgactatgat gctgtagatg aaaaatctat gtctgataat
     9121 aatacctcat cattttgtta tagaactata gctggtacaa atgtagtttc aaatcatggt
     9181 aaaggacgtg ctatagatat aaacccatta cagaatcctc aagtttctgg aaatgatgtt
     9241 acacctaaag taagtacagt ttatgctgat aggtctagca caaaatttgg aatgataaaa
     9301 aaaggtgatg attgttataa tgcttttgta agcagaggtt ggagttgggg tggctattgg
     9361 aaaaacccag attatcaaca ttttgaaaaa taatagatta gaaataaagg tgaattatat
     9421 gaatttaatg acattggaaa atataagtaa aagctattct gaaaaaaaat tactagaaaa
     9481 tatatctctt ggaataaatg aaggggaaaa aataggattt attggtgtaa atggtactgg
     9541 taaatctacc ttactcaaaa ttattgcagg agttgaagaa agtgagactg gtaatataac
     9601 aaaaactaat ggtattagga tagaatatct acctcaaaat ccaacttaca atgaaaattc
     9661 aactgtactt gaacaagtat ttaatggaac ttctgaagaa ttaaagctac ttggtgaata
     9721 tcaagaaatc ctagaaaaac ttaattcaaa ctttacagag gaattaaata aaaaattatt
     9781 atcagtacac gaaaaaatag atgccttaaa tctttgggat ttagaaagtg aagctaagtc
     9841 agtacttaca aagcttggta taaatgactt taatcaaaaa atagcagaac tttctggtgg
     9901 gcaaagaaag agagtctctc tggcatcagc ccttattaca ccttgtgagt ttttgatact
     9961 agatgagcct acaaaccatc tagacaatga tactatagat tggcttgagg aatatcttaa
    10021 ttccagaaaa ggttcattgc ttatgataac tcatgataga tactttttag accgtgttac
    10081 aaatagaatt attgaactgg acaaaggtag attattcagt tatgatggga attattcaat
    10141 atttttggaa aagaaaatgg aaagactttc gctagaagca agtattgaag ataaaagaca
    10201 aaatttaata agaacagagc ttgcgtgggt aagacgagga gctcaggctc gtagcactaa
    10261 acaaaaagct cgtttacaaa gatttgatga acttataaat agagattctt ttaaacctga
    10321 tgaaaatctc gatatatctg ttgcatcaag tagacttgga aataaaataa tagaaataca
    10381 caatatatct aaatcatttg aagaaaatac tgttatagat aatttagaat acactttaac
    10441 tcgtacagat agaattggta taataggcaa aaatggtatg ggtaaatcta cccttataaa
    10501 tatacttaat ggagaaatag agcctgatag tggatatatt tcaattggag aaacagttaa
    10561 aataggttgt ttttctcaag acgactctca tatgaatatt gatatgaggg ctatagacta
    10621 tgtaaaagaa gctagtgact atatagaaac ttcagatggt actaggatta cagcttctca
    10681 aatgtgtgaa agattccttt ttaatggtac tatgcaatat actttgatag gtaaattatc
    10741 tggtggtgaa agaagaagac tacatcttct taaaatcctt atgacagctc ctaatgtgct
    10801 tcttttagat gaacctacaa atgatttaga tattgaaacg cttaaaatat tagaagaata
    10861 cctagacgaa tttaaaggtg tagtagttac agtatcacat gatagatatt tcttagatag
    10921 aatttgtaat aaaatatttg catatgaagg taatggaaaa attcatatct atacaggtaa
    10981 ttacagtgat tatcttattt atagagagat tcaaggaatt gaatttgaag aatctaaaag
    11041 ggaatcagtt aaaaaagatg actctactac cccaaaaaaa gaaaaaccta aaaatgataa
    11101 aaagcttaag ttctcatata atgaacaaag ggagtttgaa aatattgact ctgatataga
    11161 aaaactcgaa tctaaaattg caacacttga tgaaagtact gcaaaatttt caactgattt
    11221 tactaaactc caagaaattt tagatgagaa atctaaacta gaaaaagaac ttgaatacaa
    11281 atatgaaaga tgggaatatt taaataatct agctgatgaa atagctaata ataagtaata
    11341 ttaaaataat cttaagttta ataagttttg ctttaaatct gtaatttata aatattttaa
    11401 aggaagtgtc tcaaaatgaa ctttttagtt ttatgagaca ctctttttta tgagaaatca
    11461 aatatatttt catcatttca acaatacaaa agaggcttat ctctattttg agacagcctc
    11521 tttcataatt accttctaat ttatatgctc taatatatct ataataattc ttattatatc
    11581 tatatatcca gtctttcaat atagtgacaa ttaacttcaa tatgatttaa aaatactaac
    11641 aacctttcat aaagtggatg agattcttct ccatatttag cttctaggtt cttgcctatt
    11701 tctctaacag tcctttgacc atcaatttgt aaaaaaacaa aactggaata ttcatctagt
    11761 tctatttttt tgtatttagg tattctagct tttaactttc taaaaaactt ttgaatttta
    11821 tggtcctgtt tttcaagtat agtaacaaca cgattttcag ctacttcata ttcaagtcca
    11881 tcagtaattt taaatacaat atctaaaaca tcattactct tgctcattat tttttacttt
    11941 agataaaaca ataggtaatg ctgtaagcac aactaaaact actaataaag caattgccat
    12001 tgaatttgtt gcagcaaatc cacttggtac ctttggagtt acaactccag ttacttgtaa
    12061 tattatacct attaaaccaa tgatagaacc accagcaaca agaccagaag ataaacttat
    12121 accattagaa actttaactt ctttttcttt ttcagtttta gatactaatt caacaaataa
    12181 acgaattaat gctccaacta atattataga agtagttgca attggtaaat agaatcctat
    12241 agctatagtc attattggta aatttaatgc atatagaact attgccataa atactccaac
    12301 aataatcata acccaaggta aactacctga cataatacca gaagttaatg ttgacattaa
    12361 gtttgcttgt ggtaatgcaa attgtacatt atcaccagtt gctctaagtt ggtcagaaag
    12421 taataaaatt actcctacaa caactataac accaactata cttgcaattg taaagtaacg
    12481 ttgcatttcg tttttgctac caccaataat ataagttact ttttgagatt gagtataacc
    12541 tccagctata gcaatagcaa caactataaa tgaaccaaat aaaagtaatg atttattagc
    12601 ttctaaatca gtccatccca ttataacaaa cactaatgtt acaataacta gagaagctat
    12661 agtcatacca gaaactggaa gatttgatgt tccgattgtt cctgttaaac gaccagctac
    12721 tatgacaaat aataaagata ataaaagaga tatgatagct ccaataattg ccataacaat
    12781 gttaccagaa attaagaatg ctgctaaaaa tccaataact actccaccta ataaaagtat
    12841 catttgtata gatgaacctt cttctccttc tccagcactt gatttagctt taagtgtttc
    12901 ttttatagaa gcgattatag ttggtataag ttttattgca ccaataatac ctccacaaag
    12961 catcatacca gcacctatat attttacata actactagat attgctccaa catccatttg
    13021 gttaagaggc attgcaggat tattccatac catagctcca tctttagcca tatctgtaaa
    13081 gtatcctatt aaaggtgcta taccaaagtt tgataaaata cttcctgcaa acattgttaa
    13141 agaaacttca agccctacta taaatccaat tcctaaaagt agaggattta cttcaatatc
    13201 aaatttccat ttgtagaatt tgcttcctac aagactcatt acattgtttg ctacatttaa
    13261 gaatgaacca gttaatacag taataaatcc acttattaca aatccaattc ccatgtactt
    13321 aattgaatct ccaccagcct ctgaagcaac aagtgtctca gatatagcca ttgattctgg
    13381 gtacataagt ttaccatgtt cttcaactat tagatagttg tgaactatag cagcaattcc
    13441 tataccaaat aaaactccac caactccaac agctaagcct tctaagaatg taatttggct
    13501 tccaattaat ataactgctg gtaatacgaa aataaatcca cttgcaacag attctccacc
    13561 acttgacata ccttggatta agtttttacc aagaataccc tttgaacgag caaatgctcc
    13621 aacaaaagca gaacctatta tagctcctgg aatacctgcg gcaactgtaa gaccggcttt
    13681 cattccagag taagttgtag atgcggcaaa aatggcagct aaaataatac cgataatcag
    13741 tacagctaca tttccaccgg ttctggactt atctgtgata tatggaacgt aatcttttcc
    13801 actaacctca ccataagcac ccttaggtaa ttttttgttc ataaaatttt cacccctttt
    13861 caatttgtat atattataac atatatacat ataaaactta actttttatt attttacaaa
    13921 tagcgagtca aaactactaa aatttaaccc tatattatta atttctactt ttagatattt
    13981 ttatgctaat tttcttttta tttttcaatt ctactaaaaa ctattaagat ataaaataaa
    14041 aaaatttttt aatgtaaaat taattttgta aaaaaaatgc tttaaaacac ggaaaagtat
    14101 aaaaaataca ataatcattc ttataaataa attttcacca tagtaaatat atacagaaaa
    14161 ttcttgtttt tatgcaaatt gattatttta taaaaataag tgtcataaag aaatgtctga
    14221 aatcacttta tgacacctat cataataaaa aaattattct ggtaatgctc ttttatttac
    14281 ttttccgatt ggtgtaactg gtatcttatc tatcctcatt attattgttg gaatcatata
    14341 tggaggtaga tgctcattta aatattctct aatagttctt tcatttatct taccactatc
    14401 ttcctcatca attacataat atgcacatat ataaatatct ccatcatcat ttgttctcga
    14461 tatacaaaca acacttttaa tttctgtaat attatttatt atattttcaa tctcatatag
    14521 ctctatccta aactcatcaa tttttacttg attgtccatc cttccaatat aatctaaatt
    14581 tccatcatct aaccatctta ctaaatcacc agttctatac attaacttat tatgttcaca
    14641 agttttgtaa ggattctcta caaatacttg ctctgttagc ccttttttat ttaaatatcc
    14701 tcttgatatt tgaatgcctg atagacatag ctctcctggt gctccaattg gacatagttt
    14761 gttcttttta tctaatacat atgcataagt attaaatata ggttttccta ttggtatttt
    14821 tccatattct ctgtccacat gaaaagaagt cgatacaaca gtaaattcgg ttggtccata
    14881 ctcattatat agttcataat tacgctttct atatcctttt aatctttctc ctccagtctg
    14941 tacaactcta agtgaattat tattgcaatt ttgtataaat aaccttgcaa atgctgttgg
    15001 caatgctagt atagttatgt cattttcctc acagtattca tttactgtat attcatcaaa
    15061 tttagcttct tcaggcataa tatctattga tgcacctaca agcaaataag ggaatagttg
    15121 tttcattaca gcatcaaaac tgaaacttaa gtatatacca catatatcat tttctgtagc
    15181 gcttatagat tttacgctat aataacacat atttactaaa ctcttatgtt ctatagctat
    15241 ggtctttggc ctaccagttg accctgaagt agatatcgta tatgcacaat ttgatgatgt
    15301 tattttttca gttaattcat atccaaactt aaacatttct tcatcattta tatcgagtac
    15361 tatggtattc tcatttacaa ccttactttt gagttcatct gtagttatca ctactttcgc
    15421 attactatct tcaagaaggt aattcaatct ttcttctgga ttacttgtgt ctattggaaa
    15481 aaatgctccc cctgatttca taatccctat tgctgtaata attatgttaa tatctcttgg
    15541 taacattaca gctactatgt cttcactttc cactcctata tgatttaaat aacctgcaag
    15601 tttatcagtt acttcatcca attctttata tgttaacttt ctattttcat ccctagcagc
    15661 tatattacta ggtgttacct taacttgctc cctaaataaa tcaacataac ttttatcata
    15721 gggtacttca tattgattat tattaaagtc ttccaataat actttttctt cttccttaca
    15781 tacaaattct aaatcttcta ttaaaatatc attatcttct attatttgct ctattatata
    15841 atcaaattga tttaaaattc ttctaatagt ttctctttta tatatagatg gtttatactt
    15901 tatttttatt ttaagtgccc tcttagtata tactattaca gataaatcat atcctttttt
    15961 ttctatgtca taatcatatg ataaatcaaa acttttagct ataaatattg tgtttataag
    16021 cttagtattt agatgatttt tattctctat atctgataac aaatagtatc catactctaa
    16081 agacctgctc cactgccttt ttagcttcct tacaacatct ataaattttt cactttgtct
    16141 aactcttact cttattggaa ttatattcat tgttttacca aaaactacat catcttcata
    16201 tatatacttt tgaagtataa ggccatatat agtttctatg atagagtcta tgctaatatt
    16261 gttcacttta gaatattgaa ttaacctttc atgtttctca atattcatct taaaaacctc
    16321 atctactact tcatcagaac aatctttata aaaaaaatca tttggaattt ttgctatatt
    16381 cgtataatca tctaacaaat ccatccaata attcatagct cgttctaaat taacttcata
    16441 catatcaaaa ttccccctta ctactaagtc tatagaaaaa attcttttgg aattttattt
    16501 tcacaatata taaatatatt aataatacat atgcaagctc taaaaacatg agcttgcata
    16561 aaattacact tattatgact actaaattcg taatatttac aatgtttaaa atatattata
    16621 acacatatat gattttattt ttctacattt atataatata taaattacaa atagttattt
    16681 aactaatata taacaatacc ttttggaata tgatatatta tattaattaa atttttataa
    16741 gataagttat acttatagga gggaaccata taaatgaata tttatgctca tagggggttt
    16801 agtggaaagt atccagaaaa tactattcta gcttttaaaa aatgtttgga tatggatata
    16861 tatggaatag aacttgatgt ccacagaact aaggatggaa aaattgtagt tattcatgat
    16921 gaaaaggttg atagaacttt taatggacat ggttttgtaa aagactttac tttaagaaaa
    16981 ttaaaaactc taaactcatc ttttgaagga tatcaaagca ataaagaatg taaaattcca
    17041 actttagaag aagtattaat tctaatctca cctacagacc ttactttaaa tatcgaacta
    17101 aaaactgaca aaataaacta tcccaatata gaaaaaggcg ttttagagct tattttaaag
    17161 tataatatga aaaatagagt tcttatatct agtttcaaca gcaatagctt aaaaaacttt
    17221 cataaattag accctagtgt aaaaacagga ttattgtgtt atttacctat aaacaatgta
    17281 gtcaattttg ctaaatttct gggtaatagt tatcttcatc cacctctagt tttagtaaat
    17341 gaatctctaa ttgaactttg tcacaaaaat ctacttggtg tcaatgtata tactgtaaat
    17401 gaagaggatg atatactaca ctgtctaaaa ctcaatgtag atggtatttt tactaactat
    17461 ccagatattg cttcaaatct tttacactca aaacaataca gctaattata caatagtttg
    17521 tactccttga cttttatata attaatatgt acaattttat taaatttatc ttggaggtat
    17581 aactatggat aacttattaa atgaacttga agctttaaag agtaatttag ataatctacc
    17641 aatagaaaaa atagaaaatt atgatttgag taaaactgct ttatttataa ttgatgttaa
    17701 taatggcttt gcaagacaag gtgcattata ctctcctaga gtagagtctt taataaagcc
    17761 aattgaaatg tttacaaaaa aaatatcaaa caaattaaat agagtaatag catttactga
    17821 ttctcatact cctaaatcaa tagaactttt gagttatcct gttcactgtt tggaaaatga
    17881 tgtagaaagt gaattggttg atgaacttaa gtcgatagaa aacctacaaa ttcttcctaa
    17941 aaattctact aatggttttt ttgcattaga aaatttggat tttgataata tagataatat
    18001 aattatagtt ggcgattgca cagatatatg tatatatcaa tttgcaataa ctctaaaatc
    18061 atattttaat caacataata ttgaaaaaaa tatagttgta cctatgaatt tagtagatac
    18121 ttatgatatt cctaacgttc accctgctga gattttaaac ttagtatttt tcaacagtat
    18181 gattcaaaat ggagttaatg tattaaaaga gattcgttaa gcttctaata ctttacatcc
    18241 catataatac aattatcaga tatttatttt taataaaatt tctaatagaa aaacacagtt
    18301 ttagtgagaa gattacaatt taaaacacta tctattatta ctaatcttca caatataaaa
    18361 aatcgcagtt tagatattcc ttatacaaat ttataaggaa taataaattg cgatttttat
    18421 ttttaagtag tacaattaat tgatactact tcagtattta aattcatttt ttaataatca
    18481 tacttattcg tagtttcgca cattactacc tttatttttt tattaaacat attcttatat
    18541 tctaataaaa actcatttag ttctgaatcc ataagattta tttttctatc actacaaagc
    18601 attatctttt cttggtcgat tattacatta atatcattta agtcattttt tataaatgtt
    18661 gttatacaac tctttggttg gattttttct ccatatttct cataaaatcc tgcactcttc
    18721 ttaaatgact ctaaatcttc tgtagatact ttgctggaag tattattact cataaaacct
    18781 gccgtagaag ggtcgattcc aaagtttcta agttgttttt ctacttcttc agtgtccata
    18841 ccatatctct ccataaattg cttttgtatt ttcataaatt tttcttgaga tatgttgtta
    18901 tctctcatat aatcgaatat ttttcttgaa aactcagcca tagacatctt tccatccata
    18961 acagaaaaat ataagttata tatgtattgc tcaaatttat ctacatcaga atctttaact
    19021 ttgttcttta gttcgttaaa gtctattatt ctatcatcag acatttttca tcctcctagc
    19081 taaattttta cttgtataag attataccat atttctatta tatttatata cacactattt
    19141 ttttaattta acgatttttt ctgtagcatc taattcgcac attctgccca aaggaatagt
    19201 tatcattggg atacaatgtc ctgactgaag attatatata gaaggtttat tgaccttatt
    19261 tgcaaattct attagtaatt ccatcaaatc attttcttca atacaatcct taaaatctcc
    19321 aaaaattata ccattacatt cctcaagttt tcctgaagaa tatagttgtg ttaacattct
    19381 atccagttta tattgaggtt ctccaatttc ctcaataaac aaaattttat cttttgcatc
    19441 tatttcatat tttgttccca ttgtggcaat tattaaggat aaatttcctc ccattattat
    19501 tccctctgct ttaccttcac atacagtata aatcttttct tcttttggat tttctaaata
    19561 taattcatct ttaaattcta aagcatttac caatgattta taggtaaatt tatcccattt
    19621 acctacattt gctgccatta ttccatgata tggtaaaaga ccacaatttt tatagaaagc
    19681 taaatttaaa cctgttatat cagaaaaacc tataaatggt tttggatttt gctttattat
    19741 atcataattt attttatcca atattcttgt tgttccataa cctcctctta agcacataat
    19801 tatatctaca tctttatcta aaaacatatc ttctatatcc cttgctctaa tatcatcatt
    19861 accagctaaa taacctttat aatttaaact acaactttca gaaaacttaa cttcataacc
    19921 ataactttct aaattaaact ttatttcctc caaacttgta tttcttaatg gcccagatgg
    19981 cgcaattatt cctaacattt aaacacctct tcttataaaa tgatatattc ttctccatac
    20041 taaatatctc taatataatt ataagatatt ttatttgtac ttgatacata ataatgattt
    20101 acataaaata atataattaa tgaagaaaaa taaattttta atatagttag gatgtgtttt
    20161 atgcttaata taaaaactct ttgtcatgag ataaatgatt gggttataaa tataagaaga
    20221 gatttacata agactccaga acttggatta gaagaatttc aaactaagaa aaaaattatt
    20281 aaatacttaa atgaaatagg tataaattat attgaatata agaatcatac agggataact
    20341 gcatacatta acgtgagtcc aaactttgaa acagttgcta taagagctga tatagatgcc
    20401 ttacctataa cagaagaact taattattct tataaatcta ttaatattgg caaaatgcat
    20461 gcatgtggtc atgatgcaca cactgctatt ttactgggta cttgtaatat actatttaaa
    20521 ttaaaggatt acttaaatgt aaatgtaaaa ttcttttttc aacctgccga ggaaactatt
    20581 ggtggggctc aacttatgat agaagatgga tgtcttgaaa acccaaatgt aaaatatata
    20641 tttggacttc atgtaaattc caatatcaac aaaaatctaa ttgaattaaa atacaacact
    20701 ctaaatgctt ccactgatac acttcaatta actgtacatg gttcaaaatg tcatggagct
    20761 tatccacatc aaggtattga tgctattgtt atatctgctc atattattac agctctacag
    20821 acaatcgtta gtcgaaacac aaatccaact gattctgtgg ttatttctct aggaaagatt
    20881 gaaggtggaa tcaaggaaaa tatagtttgt gataaagtgg ttataagggg tactttgaga
    20941 accttgactc ctgaaactag agagttttca aaaaaacgaa ttagagaaat ttgcgatttt
    21001 acttgtaaaa catttggagg aagtatttct gttgaaattg aggaaggtta tccagctctt
    21061 atcaattcaa accatctagt agattacgtc aaacaaaatg ctgtagaatt gtttggagaa
    21121 gaaaatatta tccttaaaga ctcgcccact cttggggctg aagacttttc gtattttcta
    21181 agacactgtg aaggagcttt ttaccacctt ggttgtgcaa atcgtgaaaa aaacattact
    21241 tcccctttgc atacctctac ttttgatatt gacgaagatt gccttattac tggtgtcatg
    21301 ctccatgtaa aaaatgtatt atcattctaa ctattaatat ttttatttat tattttatat
    21361 tgaccctcac atgatgtcat gttataccct aaaattacaa atgataaatt aaataattgg
    21421 aggtaatatt atgaaagaaa tattaataaa tcctataggt aaaatatgta ttcaaggcga
    21481 agaggtcttt attaaattag acaaaaagta tgtacctgca ttaaatgaac tcgacgattt
    21541 cagtcattta aatgtatttt ggtgggctga tgggtttgat aatcctgaac taagaagtat
    21601 tttagaaacc ccaaaacctt ataaaagtgg accagacgtt ataggaatat ttgcaacaag
    21661 gtcacctata agacccaatc caatagcatt gactgctgta caaattatca atatcgacca
    21721 tgaaaatggt ataataaaaa taccatatat tgatgctaat gataatagtc ctgttataga
    21781 cttaaagcca tatactccaa gcgttgatag ggttgaaaat ccgtccattc ctaaatggtg
    21841 tagtcactgg cctaagagtg tagaaaaatc aggagaattt aattgggaag atgaaattga
    21901 attttaaatt acttttttct tgatttcatt aacttgtttt ccacatttat tttatttaca
    21961 cttaccaaga ttttatgtca catata
//
LOCUS       DAYAKB010000059        21752 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.059, whole genome shotgun sequence.
ACCESSION   DAYAKB010000059 DAYAKB010000000
VERSION     DAYAKB010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.059"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(8..850)
                     /gene="licT"
                     /locus_tag="ACGI3L_002667"
     CDS             complement(8..850)
                     /gene="licT"
                     /locus_tag="ACGI3L_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFG9198365.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1111..3153)
                     /locus_tag="ACGI3L_002668"
     CDS             complement(1111..3153)
                     /locus_tag="ACGI3L_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFG9198366.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(3305..4276)
                     /locus_tag="ACGI3L_002669"
     CDS             complement(3305..4276)
                     /locus_tag="ACGI3L_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198367.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(4277..5254)
                     /locus_tag="ACGI3L_002670"
     CDS             complement(4277..5254)
                     /locus_tag="ACGI3L_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198368.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            5473..7032
                     /locus_tag="ACGI3L_002671"
     CDS             5473..7032
                     /locus_tag="ACGI3L_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9198369.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGESKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            7138..8097
                     /locus_tag="ACGI3L_002672"
     CDS             7138..8097
                     /locus_tag="ACGI3L_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198370.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPAYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLAKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            8100..8912
                     /locus_tag="ACGI3L_002673"
     CDS             8100..8912
                     /locus_tag="ACGI3L_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198371.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(9128..10030)
                     /locus_tag="ACGI3L_002674"
     CDS             complement(9128..10030)
                     /locus_tag="ACGI3L_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9198372.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            10385..11563
                     /locus_tag="ACGI3L_002675"
     CDS             10385..11563
                     /locus_tag="ACGI3L_002675"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFG9198373.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            11572..12228
                     /locus_tag="ACGI3L_002676"
     CDS             11572..12228
                     /locus_tag="ACGI3L_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HFG9198374.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            12228..12893
                     /locus_tag="ACGI3L_002677"
     CDS             12228..12893
                     /locus_tag="ACGI3L_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HFG9198375.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            12998..13774
                     /locus_tag="ACGI3L_002678"
     CDS             12998..13774
                     /locus_tag="ACGI3L_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HFG9198376.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            13836..15170
                     /locus_tag="ACGI3L_002679"
     CDS             13836..15170
                     /locus_tag="ACGI3L_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFG9198377.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            15666..16598
                     /locus_tag="ACGI3L_002680"
     CDS             15666..16598
                     /locus_tag="ACGI3L_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFG9198378.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPNNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNNNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVAT
                     KKSQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSE
                     GHRKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(16990..20529)
                     /gene="nifJ"
                     /locus_tag="ACGI3L_002681"
     CDS             complement(16990..20529)
                     /gene="nifJ"
                     /locus_tag="ACGI3L_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFG9198379.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPVNT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMGICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(21047..21616)
                     /gene="pduL"
                     /locus_tag="ACGI3L_002682"
     CDS             complement(21047..21616)
                     /gene="pduL"
                     /locus_tag="ACGI3L_002682"
                     /EC_number="2.3.1.222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HFG9198380.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         7493 a         3435 c         3008 g         7816 t
ORIGIN      
        1 ctctttatta taaattcagt acagatataa ctcttttgat atgtaatgtt aaataaagta
       61 gttcatcttg acttacatag taatcataat tcttttctac atgagttttt attttatatg
      121 cacaatcata atccttttca tactttactt taattatatc tataatttca ttatttgtat
      181 cattgatttt ttcttttttt actaatcgtt ttgcaaagaa ttttaaatga gtcagaagcc
      241 tatcataatt tatatcatct tctttaaatt caactctata ataatatctt ataatattta
      301 gtatgtcttt tacaatttta gtaattaaca gtgattcctt tgaacttccc ttatagtttg
      361 aatttactat atgcattgct ataaaaccag cttcatctac tggaaatttc acatcaaatt
      421 ctttatttat ataatctaca gcccatttcc caatctcata ttctttttta tgtattcttt
      481 ttatctcatg tagtaaatca ttctttatag ttatgttttc atgatatctt ttaattgcaa
      541 atgcaatatg gtcagtaagt gctacataaa tatattcata aagtttagta ttcaaattct
      601 cctctgcata agcaattatt tcagtactaa cctcaaaaaa tttctcatca acctggcttg
      661 ctagtttact aattttatct aaaaagcttt catcttgtat tacaaaagtt ctttcaattt
      721 tacttttatc tatttcttga cctttctttt tttgaaaccc aattccacat cctgttaata
      781 ttaattcttt ttttatattt tcatctaaaa ctaatacaac attattatta taaatttgtt
      841 gaataatcat aatcaatatc tctcccaaaa tacaatttcc cttattcata aaaaaatacc
      901 taaattaaga tacaattcac ctgtatacct taacctaggt attgcctgct taccagtaac
      961 aatccagctt gttaacgctt atatattgta ttcaatttat ggttttattc tattataaat
     1021 aaatatatat gtcaagtaaa ttattgaaaa ctatttccta ttttttagta ttaattttaa
     1081 catcaaaaat caaattttat tccattatat ttatgattct atcatcatca tttcatcata
     1141 gagaatattt tccaataact ctttagccac ttctcttgat atttgcttag tttcaactaa
     1201 ttgttgaaca ctgtctcttt gactttgtat cgccattact ctgtagtatt ctactcttgc
     1261 ctcaaactta tcatcatttt gaatctttct agtaatccaa ttcaaataac gattatagaa
     1321 tctgattgct attaaggcct catgtctgtt atcttcatca gtatttttat ttataaatga
     1381 tatagcagtt ttagtagaaa gtgcatatgc atggtgaaac tctttgatta tttctttatt
     1441 ctcagatact atttttgtaa ttttttcttt tacttctttc tttacttttc tatttataat
     1501 ccacatgctt atttttaatt ttacaatttt aaatatagat ttttgaacag attttcttga
     1561 ttttgtaata taaaatctat acaatttaaa ggctctatca gaaattttac catcttctaa
     1621 tagtttcaaa acagctaata atccctgttg gtctgcttct gcaatcatca tacttataag
     1681 tttattatct ggagtattta gtattccttt ttctgagtct accaactgtt catttaaatc
     1741 atgtataact ggttgtactt cttgtgcttt ttcattacta agttttaaaa tggcttcttt
     1801 caaaattagt ttatatgcct ctttatcaga taataaaggt tctgactctt gtacgttatt
     1861 ttttaataat cttggcagta aaactgttgc caatactaaa cttataagaa taacttctga
     1921 tgatataaat aaaacagtat ctctcattgg aaatacatct ttatcagcca aataaaaagg
     1981 tatagataag gcagttgcta gtgtaaatgt accatgaaca ccacaagtag caactattag
     2041 tgagtattta catttagaaa tactctcttt tacaacttct tcatccttaa aacctaaaaa
     2101 acctacaaaa aaattattta aaggattctt tttaggtttt ataaaagaat tatgccataa
     2161 atatacccat ataaatctta taacaaataa aataagtaca attaaagtag aaataaaagt
     2221 caattccaat gccatatttt catttttact actaagtcct gtatatatac ttggtaacaa
     2281 aaaaccaagc agtgtaaaga caaatccatt caatacatac tccaaaacat accaagtatt
     2341 gtctgatatt atccttaatt tagtagttgt attttgtaaa tgctcttttt caattccatg
     2401 agctatccct gccattacaa cagctaggat tccagatact cctatttctt ctgctacaaa
     2461 atatacaaaa agtggagtca ttatttgtat aactattacc attggaattt cttccaaatt
     2521 ccacttgtgt aaactaagtc ttatttttat aattatgtat cctaaaatac ttcctactat
     2581 tattcctcca aaagctgtaa tcataaattg aatccctgcc tcttctattg aaaaaactcc
     2641 tgtaactgtg gcaagtactg caaccttaaa tgctactact ccagcagcat catttaataa
     2701 agattcacct tcaagtatac tcatcatatt tttaggaaaa tttaatcctt gtgtaattga
     2761 ttttactgct actaaatcag ttggagatat tactgctgcc aaagcaaatg aaacagataa
     2821 tggcatccca ggaataagaa aatgtataaa gattccacct gcaaacacgg ttattaaaac
     2881 taaaccaaat gcaagaagca aaattggttt tctgagctct aatagctctt ttctcgatac
     2941 attttgtcct tcactgaata gtaatggagc tatgatacat attacaaata tttctggatt
     3001 aaatgaaaat gagaatttaa atggcaaaat agacaatata atccctagta caatttgata
     3061 tattgcaaga ggaatattac tccacttttt gctaaataca gttgaaatcg ttgtacaaac
     3121 caataatccc aacaatgtta ctaaaattga cataactacc tctcttttca ataataatat
     3181 tatagattaa acttatatat caactaactt aatattaaca gcatgaaatc ccatcttaat
     3241 caaaaaaatt ttcagtttat tctattattc ttattatata catcaaattt aatttttgaa
     3301 atatctatac tagatgacat gcaacaaaat gatttcttga tatttctttt aaaactggaa
     3361 tctctttttt gcatatttcc ttacaataag ggcatcttgt atgaaactta catccacttg
     3421 gtggatttgt tggagatggt atgtctcctt ttaatataat tctatttttc ttaattgtag
     3481 ggtcttgtat tggtactgcg ctcataagcg cttttgtata tggatgttga gaatgtaagt
     3541 aaagttctcc tttagttgca atttctatta tagaacctag atacataaca caaactctat
     3601 gtgcaatatg atttactaca ctcaaatcat gagatataaa taaatatgaa agtttatatt
     3661 tatcctgtaa atccataagt aaatttataa tttgagattg aatagaaaca tctagtgcag
     3721 aaacaggttc atcacaaact ataaattctg gatttaatgc taatgctctt gctataccta
     3781 ttctctgtct ttgacctcca gaaaactcac ctggttttct atttaaatgg tacttagaaa
     3841 gaccacaact ttctacaaca tttaatatat tatcttttat ttcattcttt ggcactaaat
     3901 tatgttctat aactgcctcg gatattattt gttccacatt taatcttgga tttaatgaac
     3961 tatatgggtc ttgaaatatc atttgcattt tgggtcttaa ctttctaagt tcttccttct
     4021 ctaacttata tatatctaca ccattaaatt caactttacc ttcagttttt tcaattaatc
     4081 taagaatggt tcttcctgca gttgattttc cacatcccga ttctccaact atagccaaag
     4141 tttctccttt ttttaaatca aaagaaattc catctactgc ctttacacat ttaatttcct
     4201 tatcaaataa tccagattta acttcaaagt actttttaag accttctact tttaataaac
     4261 tctcttcttt tttcaattat atctcctcct ttttatataa ccaacatgca atactatgac
     4321 cactattcaa ttctattaaa ggaggtatct gagttctaca tttatcacat actttttcac
     4381 atctatcact aaaataacat gaatctggca tcccaattgg atttggtact tgtcctggaa
     4441 tcgaatacaa tcttttatct ttgttttttc caagagcagg ctttgatttt agaagtccaa
     4501 tagtataagg atgttttgga tttttaaata attcaacaac ctctgccact tctataattt
     4561 tgccagcata catcactaat actttgtcac acatttctgc aactactccc aaatcatgtg
     4621 taatcatcat tatagatgtg tttaattttt cttttatatt tttcattata tctaaaatct
     4681 gagcttgaat agtaacatct aaagctgttg ttggttcatc agctataagt aattttggat
     4741 tacatgataa agccatagct atcattattc gttgtctcat tccacctgat aattcatgtg
     4801 gatatgaatt atatatttct tcagctcttg gtatttctac cagttttatc atatcgatta
     4861 cctttttctt agcttcttcc tttgataaat cttgatgtat cataatacct tcaatgattt
     4921 gacttccaat agtaaacgct gggtttaaag atgtcattgg ttcttgaaaa atcattgata
     4981 tctcattccc tcttattccc ataagttcat cttcattcat ctttaaaata tctttgcctc
     5041 gaaagattat ttctccacct tctatttttg atgttggaag taacttcatc aaagacatgg
     5101 ctgttacaga cttaccacat cctgattctc caactattcc aatagtttca ccttcattta
     5161 tattaaaact tacttcattt acactcttta caatcccttt atctgtatga aaataaactt
     5221 ttaaatcttt aacctcaatt agtgctttac tcattatttt ctcctctcag caaaattact
     5281 taagataaca tacacctttt gattgtattt tataaaaatt taaattacaa cattttctta
     5341 cattttatta tttttttcta ttaattataa taatataata gttaatttct atatatattg
     5401 atttaataat gattactatt atacaataaa aaatatgtgt taaatattat tttatggagg
     5461 ttttataaga atatgaaatt taaaaaattg gcatcattaa tcttagtttc atcattaatg
     5521 cttacattta cagcctgtgc ttccaatgat aaagacaagt ctagtggaag caaatctggt
     5581 ggaactgttg taatacctat ggcaagtgac ccagatataa tcaatggagc ttttgcaaac
     5641 gttaaagaag actctcttgc atcaaatata gtttatgctc ctctttatac ttatgaaaaa
     5701 ggaaatttag taaattattt agcagaaaaa gtagatttta aagatagtaa ggaattaact
     5761 ataaaattaa aatccaattt aaaatggcat gatggaaagc caataactgc tgaagatgtc
     5821 ttatttacat ttaatacagt tttagacgaa aaacaaaatt caccatcaag acaatactta
     5881 ttggtgggtg agaaaccagt taaagtagaa aaaattgatg atttaacagt taagattact
     5941 ttaccaactg caagtgaatc tttcttatat ggtatatcta aaatttctcc aataccaaaa
     6001 catgtgtttg aaggagaatc aaatatagct aagtcagaaa aaaataataa tccagttggt
     6061 tctggtgcat tcaagtttaa ggaatggaaa aaaggtgaaa gcatagtatt tgaaaagaat
     6121 gcagattatt ttggtggaga atctaaggca gattctatag cgctaaaaat aattcctaat
     6181 gaagcatctc aagaagcagc tttaaataat ggcgaaattt cacttatgaa gacatctgct
     6241 gaaggatatg aaaaggcaaa atcaaactca aatttacaaa cttatactta tagtgaagaa
     6301 agattaaact acattgtatt taaccaaaat atatcaaaca tggctaacaa agaagtaaga
     6361 caagccttat catatgcctt aaatagaaat gaaatgatag aatcagcata tggaaaagaa
     6421 ggttctgtac ctgctaaatc tatattagtt ccagaagcag acttctatac agaagaaggt
     6481 gttgaaggat atgaccaaga tacaaataag gctaaagact tattggataa aagtggtgtt
     6541 aaaattgata aattaaaaat aggttataac acaggtagat ttgggcataa aaactatgcc
     6601 ttagtagctc aacaagagtt gaaaaaaatt ggtatagaag ctgaaatagt tccttatgaa
     6661 agtaaggcat tcttcaatat actatttagt aatagcactg aatgtgatat gtatgtaaat
     6721 ggttatgctt ggggattaga accaaaccca tatagaggta tgtttgaaac tggtcaatat
     6781 tgcaaccaaa ctaaatattc taatgctgaa atagatgctt tatgggaaaa aggatttact
     6841 gagttaaaca aggaaaaacg tgaagaaata tataagcaaa tacaacagga tatatctaag
     6901 gatgcgccta tttacactat agattatgaa caaaatttaa tggcagctca aaaaaatcta
     6961 aaaggaataa aagatgctaa accatctcct gcaatattat ttgaagattg gtctaaactg
     7021 tatgtagaat aattgatgta aaattttata ttattaatta gaaaaggaga tgtctaaaaa
     7081 taatattgtt ttattatttt aaaacgagac atctctttta attaggagaa tttacttatg
     7141 ttaaaattaa tattgaatag agtaaaagtt ttaataccta tgttaatctt aatatctata
     7201 ttatcatttg gacttttaga attagctcct ggtgacccag cagatgcata tataaatcct
     7261 ttaatgtctt cacaggatat tgaaaatata agggttaata tggggcttga taaaccagca
     7321 tatataagat atttaaactg gttgaaaaac actttaagtg gaaacttagg tatttcttat
     7381 ataaaccata tgcccgttac agaacaaatt atggaaaaaa tgggaaatac atttattctt
     7441 atgggtactt ctttgatatt ttcaatattg gtagccatac ctcttggaat atttttagct
     7501 gtaaataaaa attcaataac tagtaaagta tcatctgttt ttaattatat aggtgtttct
     7561 ataccttctt tttggatagg tatgatactc atttcaattt tttcagttaa acttaacatt
     7621 ttcccatcag gaggtatgca tactattgga aatgatagta ttggagattt agcaaaacat
     7681 ttagttttgc ctgtaataac tttaggtcta tataatactg ctatttttac aaattatgta
     7741 gaagctagtg taaatgaaca attaaaaaaa caatatgtta ttacagcaag agcaaaagga
     7801 ttatcagaaa aagtcatact atttaaacat gtcttgaaaa attcactgac atcattggtt
     7861 acaatcctag gcatgagtat acaaaaatta gtcactggtg catttgttac agaagtagtt
     7921 ttctcttggc caggtatggg aagattaatg attgattcaa ttttttcaag agattatact
     7981 gtaattatgg caataactat gttatcagca ctatttttaa ttttaggtaa tttagttgct
     8041 gatatactat acttattaat tgaccctaaa ataaaatcta gcaaaggagg attctagttg
     8101 tgtttacaag tatcttaaaa aaattaaaaa aagataaatc ctttgctttt gcatgtatta
     8161 ctcttagcat aataatcata ttaattatag cttcttttat attaaatata gactctaatg
     8221 caattgatac tacttctaaa cttcaagaac ctagcttaaa gcatatcttt ggtacagacg
     8281 aacttggtag agattacttc tctagagctc tttatggtgg aaggatttca cttagtgttg
     8341 gtattttatc aatgcttatt tctgtagtat ttggtactgc tgtaggtgtt attagtggat
     8401 atattggagg taagctagac caattcttga tgagattagt ggatatgctt atgagtatac
     8461 caagtttctt agttttgatt gtattaaata cttatctaac acctaaagtt tccactatta
     8521 tactaattat tggattctta agttggatgg aagtttcaag aattgtacgt ggcgaaacat
     8581 taaaaataaa ggaaaatgaa tactgtctag ctgctaaagc tactggtatc aaaactagaa
     8641 atatactatt aagacatata gttttaaact taaaagagac tattgtagtt gctggttcgt
     8701 taaatattgc taatgctatc ttaactgaat ctgctcttag ttttttaggt cttggaatcc
     8761 aattgcctct tgcatcatgg ggtaatatgc ttcaagatgc tcaaagacat atttttgaca
     8821 agttatattt agctgtattt ccaggattac ttatattttt aacagtcatg agtttgacta
     8881 taataagcaa aaaattttct agtaatactt aacaaatttt atatagaaaa taaaaacagt
     8941 gattatctaa agatatacac tgtttttatt tttcgtttaa aaaaatacat attttgtata
     9001 ttataacttt aaatactact ctaccatgtt atgcaaagcg tattattgct ctcaaacata
     9061 tagatgaaaa actaatagtt tattataata aaaattgatt tatttatttg ttattttaat
     9121 aacattttta agagttcttt ttactaaaga aatctataat aaatttaaat acatgttggt
     9181 ctacatggct ataacgttct tttttaggtc tacataatat aactttccat gtaataggat
     9241 gattaaaagg cttttctata attttgctat tttcaaaaaa atcatgaact ggtgatggta
     9301 aaattgttat aaaatcagaa tttgtggttg atagcaacaa aaaatcccat gaaccagaca
     9361 ttatatatct ttttaactta acattttcat cagtaaattt ttgcattagc ttatgatgta
     9421 tcataaaagt aggattaaat attgcaagta actgctcatt caaatcgttc caatctatct
     9481 tatccttctt agcaagtgga tgatttatat ttaaaaatgc tgtaagttca tcttcttgaa
     9541 gcacatgttc agttactaca cttttatcaa ttttatgtgg atgtaacaat actgcataat
     9601 ctaattcctg taagataagc attctattta agtcatatgc acccttctct actatatcaa
     9661 attctatatc tggattattt gcaactaact gtgcaactac atctgaaaat gctattccaa
     9721 gtataagtgg aggtattcct attctaactt ttcctttaaa ttgaactgaa tcttctctta
     9781 aatcttccat catatttttg tattcattta tgatatgttc tgcatttaca taaaatcttt
     9841 ctcctgctgg tgttaaccca tttaacctgc ctttatacct ttcaaataaa tatacatctt
     9901 cactttcttc aaaatttttt ataatttgac ttaatgctgg ttgagatatg tgaagtgtct
     9961 tagatgctat tgataaatta aaaccagatt tcactatttc aacaaaatat ttcaactgtt
    10021 ttatatccat tttaaacccc cttccccaaa agtataattt agattatatt ttttcttcta
    10081 atgatatttt ataggaaaat caacataatt tcattaatat tttaacaaaa tatttttcta
    10141 aatctactat aaatttttat cctataaatt tttcttatac actatataaa aaattagact
    10201 tagacaaaac gcttttttcg ccgtaatcta taattagaaa caggaaaacc taaagcatta
    10261 ggaataaaag taattgaaat acttaaaaac aagcttgtat taaaaaagta ctttattata
    10321 gtgttcccta atttctttat tcagaaaatt tttaattatc attcaagaaa ggtaactatt
    10381 agatatgaaa gatgtagtaa tcgtatcagc agtcagaaca cctataggaa gttttggagg
    10441 tgtatttaaa aatacttcag ctgttcaact tggaactatc gctgttaaag aagcgatatc
    10501 acgtgtaaga cttaatttat ctgaaataga tgaagtaata attggaaatg ttcttcaaac
    10561 agggcttgga cagaatgttg ctagacaaat tgctataaat gcaggtatac caaattctgt
    10621 tccaagctac acagtaaata aattatgtgg ttcagggctt aaaagtgtcc agctagctgc
    10681 ccaatcaatc acatctggtg aaaatgatgt ggtaattgca ggtggtactg aaaatatgag
    10741 ccaagctcct tatatcgttc caactgctcg ctttggtagt aaaatgggtg acataaccat
    10801 ggtagatagt atgctaacag atggccttat tgatgctttc aatcagtatc atatgggaat
    10861 aactgcagaa aatattgcaa ctaaatttga atttactaga gaaatgcaag ataaattggc
    10921 attagaaagt caaaataagg ctgagaatgc tataaaaaac aaccgcttta aagaagaaat
    10981 cgttccagta gatgttttaa tacgtcgagg aaaaatagaa actattgata aagatgaata
    11041 tcctaaatta ggtatgacat ttgaaggttt atctaaactt aaacctgcat tcaaaaaaga
    11101 tggtactgta acagctggaa atgcctcagg tattaatgat ggtgcggcta tgttaatact
    11161 aatgagccaa caaaaagcag acgaactagg tattagacca cttgctaaaa taaaatccta
    11221 tgcttcagct ggtgttgaac ctgaagtcat gggtactggt ccaatccctg caactagaaa
    11281 agcactgaaa aaagctggac ttagcatcaa tgatatagac ttaatagaag caaatgaagc
    11341 gtttgctgcc caagcattag ctgttaaaaa tgaacttcaa atagattcat caaagttaaa
    11401 tgttaatggt ggtgcaatag cattaggaca tccaatagga gcaagtggag ctagaatact
    11461 tgttacctta atttatgaaa tgcaaaaacg taaagttgaa actggacttg caacactttg
    11521 tattggtggt ggtcaaggaa tatcaatggt ggtttcacga taggaggaaa tatgaataaa
    11581 atagttagca ttgatgaagc tctatctcat gtaaaagatg gagatacaat aatggttggt
    11641 ggattcatgg ccaatggttc accagaaaat ttaattgatt atttatgtag taaaaatata
    11701 aaagatttga cactaatttg caatgatact ggctttattg acaaaggagt tggcaaaatg
    11761 gttgtaaata agcaatttaa aaagataatt gcttctcatg taggattaaa taaagaaact
    11821 ggaagacaaa tgaataacaa tgaaacagat gttgagttag ttcctcaggg aactcttgct
    11881 gaacaaatac gtgcagctgg ttatggtcta ggaggtatac tcacaccgac tggtattggt
    11941 actcttgttg aggagggaaa gcaaaaaatt gttgtcgata gcaaagaata ccttcttgaa
    12001 aaaccaattt atgcagatgt tgctcttcta tttgcatcaa aggtcgataa agcaggtaat
    12061 ctagtttata aaggctctat gaacaatttt aataatttaa tggcatctgc tgccaaaatt
    12121 acaatagttg aagcagatga aatcgttgaa attggtgata ttgacccaaa tgaagttaat
    12181 acaccaggta tttttgtgaa ttacatcgtt gaaggaggta atttataatg gataaattag
    12241 aaatgcaaga atatattgca aatagagtat ctaaagaatt aaaagacgga gccgttgtaa
    12301 accttggaat aggtctacca accaaagtag caaattatat tccggataat gtaaacgtta
    12361 tcttacaatc tgaaaatggc tttttaggtt taggttcagc cgaagatgga aattcaagtg
    12421 atgaaactat tgtaaatgca ggtggtcaac cagttactat acttcctgga ggatgtttct
    12481 ttgatagtgc tacttctttt ggaataatca gaggaggtca tgttgatata actgttcttg
    12541 gcgcacttca ggttgacaaa tatggcaata tagcaaacta tatgattcca ggtaagatgg
    12601 ttccaggtat gggtggagct atggacctag taactggagc taaaaaagtt attgtagcaa
    12661 tggaacatac ttcaaaaggt tctgcaaaaa tattaaataa ttgtactctt ccacttactg
    12721 caacaaatgc tgtagatttg atagttactg aaatgggagt tatggaagta acatcagatg
    12781 gaattttact taaagaaata aatccagctt tcacattaga tgatgttatt tctgctactg
    12841 aagctccttt aatattgtca gattcattaa atggaaaaat atctgttgtt taaaataatt
    12901 aaaactagaa aataaaaatc tcttagacgt attacatata aatttgtatt gcttaaaata
    12961 ttaatataaa aataaaataa aattggagga aatgaaaatg gttaaagata aagttgtatt
    13021 cgtaacagga gctgcaagtg gaataggtaa acaaatagct gaatcgttct taaaaaatgg
    13081 tgctaaagta atgttctctg atataaatca agaagcttta aataatacca taacagagtt
    13141 acaaaaaaaa ggttatgatt gcatgagtgt aaagtgtgat gtaactaagg aagaagaaat
    13201 taaccacgct atagacaaaa ctgttgaaaa gtatggcaga ttagatatat taataaacaa
    13261 tgctggactt caacatgttt ctatgataga agatttccca actgataaat ttgaatttat
    13321 gataaaaata atgctgacag caccttttat agctactaaa aaagcatttc ctataatgaa
    13381 aaaacaaggc tttggtcgta taataaatat ggcctcaatc aatggtgtaa taggatttgc
    13441 tggaaaggct gcttataact cagcaaaaca tggacttatt ggactaacaa aagttgctgc
    13501 tcttgaagct gccgattctg gtataacagt taatgcttta tgccctggat atgtagatac
    13561 tccacttgtc agaggtcagt tcaatgacct ttcaaaaact cgtaatatac cattggaaaa
    13621 tgtcttagag gaagttttat acccacttgt accacaaaaa cgcctattag atgttcaaga
    13681 aattgccgac tatgctatgt tcttagcaag tgataatgct aagggtatta caggacaagc
    13741 ttgcttacta gatggaggat atactgcaca atagttatta tatttagggc ttgaagaaag
    13801 tattcttcag gtccttctac taaggaggga tatttatgag tattatcgcg ccaattggta
    13861 taattattgg tatcatagct attatatatt tttcagttaa agaaattcat ataactatag
    13921 ctgctccaat agcaacttta atagttgtta ttttaaataa aatggatgtt gtaacgtcaa
    13981 tgctaggtgc tgacaaaaac aattatatgg gtgcacttgg aaactatata atgagttatt
    14041 ttgcaatatt cttattaggc tcaatacttg ctaaatttat ggaagaaagt ggagctactg
    14101 tatcaatagc tgattttatt ttaaataaat ttggctctaa tcatccttat agagttttag
    14161 ttgctatatt tatagtaagt tttatattaa cgtatggtgg tataagctta tttgtagtta
    14221 tgtttgcggt cattccactt gcaagaactc tatttaaaaa acttgatatt tcttggaacc
    14281 ttattcagat accactttgg cttggtattg caacaattac tatgactata attcctggaa
    14341 caccagccat tcaaaatgtt atacctattc aatatctaaa tacgtctctt actgcagcta
    14401 ctataccaag tattgtaggt agtataggtt gtgctacatt tggacttgtc tatatgaaat
    14461 atgctctaaa caaaagtatt agaaaaggtg aaacttatgc aacttacact tcagaattag
    14521 aagaagaatc tttagataga gaattaccag gattttttgc aagtattttt cctctattag
    14581 cactcgtaat tatagctata actggaagta cttttggttc agaatttatg aaaaaaaatg
    14641 taatttacat agctttaata gttgcaattc ttttatctgc ttttttattc cataaatttc
    14701 tatcatctaa gatacagaca ttgagcatag gtgctagtgg ttctataggt cctatatttg
    14761 ctacatcttc tgcagttgca tttggagcag taataatggc tgcacctggt tttgatgtat
    14821 ttagcaaact tataatgtca ataccaggta gtccacttat aagtcttact gttttgactt
    14881 caacaatgtc agcaataaca gggtcctctt ctggtgcatt aggaatagta atgccaaact
    14941 ttgcagatta ttatttaagt actggtctaa atccagaatt aattcaccgt gttgctacaa
    15001 tagcttcaaa tatactaact atagttccac aaagtggtgt ttttcttaca ttcttaagct
    15061 tatctaagtt aacacataaa actggattta aagaaacttt cattgtagtt gcagttggtt
    15121 cactaatagc agaaattatt gtaattacat taggattact aatgtattaa tataaaacaa
    15181 gttaaaattc ataatatgaa aggtggtgtc tcaaagtgaa ctttttactt aatgagacac
    15241 tctttttata tgaaataaca tatgcctatc atttaaacaa taaaaaaggc cttatctcta
    15301 ttttgagaca gacccttttt atttcttaaa gatttaaata attataattt gttgctaata
    15361 cgaaagcatc tactgaataa atttaaccaa ataaaaaaaa atttatcata actataaatt
    15421 tacgttatgg aattattata aaaatattat tttctctaac taagtaattc catactatac
    15481 aggcttttaa tacaaattgt caaacacact gaaatatacc tatttattcc atatatatct
    15541 tttttacata tctttacagt aaaaaaagtc ttaatcttat gttagtatag attcacgggt
    15601 aaccccctac actaaaggtt acaaatcagt aacattttta gaatttttag attaagaggt
    15661 gtttaatgat gagaagaaat ataccaacaa aattaaaaac tatattagct ttaggagtgt
    15721 taactttagc aacagcttca agtgctgtta ctgcaagtgc ttcatcactt gaaaataatg
    15781 taaatataag taacaaaagt ttagtatata gtaatactaa atacaagttt tctgcaaaac
    15841 caaattgttc tgtaaaacca gaacttaagc ctgataaaga taactcttgt aaggataaga
    15901 atcataatga caagaattgc aacaacacta ataaacctga ggacaacaat aattcagact
    15961 ctactaataa gcctgataac aataaacctg agtctaataa acctgaagac aacaataatt
    16021 caggctctac taataaacct aataataata aacctgagtc taataaacct gaagacaaca
    16081 ataattcagg ctctactgat aaacctgata acaataaacc tgagtctaat aaacctgaag
    16141 acaacaataa caataattca gactctacta acaaacctga tgataataac aactcaggct
    16201 ctacaagtga aagtttttca gcttaccaaa aagaagttgt tgacttagta aatatagaaa
    16261 gagctaaagc tggattaaat cctcttactc ttgattcttc tatatcaaat gttgctacaa
    16321 aaaaatctca agatatgatt gataacaact atttttcaca caattctcca acttatggtt
    16381 ctccatttga catgttgaaa aaatttggaa taagctataa gacagcaggt gaaaatatag
    16441 ctatgggtca aaaaactcct aaagaagttg taaacgcatg gatgaattct gaaggtcaca
    16501 gaaaaaatat aatgaatcca aatttcagta aaataggtgt tggagtagca caaaaaagtg
    16561 gtggttcaat ttattggaca caaatctttg taggataaaa tactcttttt ccatacatat
    16621 caaaagagta tctctaagtg ataaaaaaca caaatgagat actcttttgt atctatttta
    16681 aaattatcaa atccaaatat acatactata aatattattt gttctcttaa ttttagtgtg
    16741 tagaacaata tataaaaagt attggcaaga tgaaaatgga aaacttaaaa aagatattta
    16801 ataggtaaaa acaaaatctt aatatcttca taaaaaaagg ctgtctcaaa atagagataa
    16861 ggcctttttc attgttgaaa tgattaaaat atatttgatt tcatacaaaa agagtgcctc
    16921 atgaactaaa aagctcactt tgagacactc tcttttatca atttatataa gcattataat
    16981 actttaatat tattcagcta attttttgta tccttcatat ctttctttag catcagcttc
    17041 agctttagca aataatccat cagcttcttc tgggaattgt ttagctatag cagaatatct
    17101 tacttgtgca agtatgaaat ctttgaagct tgcagttggt tcttttgaat ctaaagtgaa
    17161 tgggttttta ccttcagctt ttacttctgg attgaatctg tataaatgcc agtatccgca
    17221 agcaacagct tgtgcttcgt tagctacagt tcttcccata ccttctttta atccatggtt
    17281 tatacatgga gcataagcta ttattagaga tggcccatca tgtttttcag cttctataac
    17341 ggctttgata aattggtttt tatcagcacc catagcaact tgagctacat atacgtttcc
    17401 atatgtcata gccatcattc ctaaatcttt ctttctagat tttttacctg aagcagcaaa
    17461 cttagccata gcagcagctg gagtagcttt agaagcttga cctcctgtat ttgaatatac
    17521 ttctgtatca aatacaagta cgtttacatc ttcaccagat gcaagaacat ggtctaatcc
    17581 accgtaaccg atatcatatg cccaaccgtc tccacctagt atccattgag atctcttaac
    17641 tagataatct tttctatctt ttatagcttt tactaactct ttagcttttt catctgtaca
    17701 atcacaagct ggtttttcta ataattcaac aaccttagca cttgctactt tagaagcttc
    17761 tccatcattt ctagaatcta accactctgt aaatactgct ttagcatctt cacagatacc
    17821 catagaaact aactctgtca tagcatctac tattttattt cttatttgct taacagctgt
    17881 gtacatacca aatccatatt cagcattatc ctcgaataaa gagtttgccc aagatggacc
    17941 tttaccttca tggttacaag tataaggaat tgatggtgca gaagctcccc atatagaaga
    18001 acatccagta gcattagcta tcatcattct atctccatat aattgtgtaa ctactttaat
    18061 gtatgcagtt tctccacatc cagcacatgc tcctgaaaac tccattaatg gttgtctaaa
    18121 ttgacttcct ttaacagtgt ttacaggcat aacatcacct tttggagcta cctcatcagg
    18181 atttactgca aatgcccaat tatctaactc tgtatcaagt tgagtatcta ttggcttcat
    18241 aactaaagct ttttctttag ctggacatat gtcagcacag tttccacatc ctgtacagtc
    18301 aagtggacta agttgcattc tatattttaa tccttctaat cctttaccta atgctttttt
    18361 agcttcaaat ccttctggag cattagctaa ttcttcttca gtaactaata ctggtcttat
    18421 acatgaatga ggacatataa aagaacattg gttacattga atacagttat ctattatcca
    18481 ttcaggaaca tcaacagcta taccacgttt ttcataagct gcagtaccac aagggaatgt
    18541 tccatcttct ataccattga atgtacttac tggtaagttg tttccttctt gtgcagtcat
    18601 tggtcttagt atatttttta taaattctgg ttctttaact tctcctttat ctgcatcaac
    18661 agcattttcc caagaagctg gaacttcaac tttaactaaa gcatttattc ctgcatcaac
    18721 agcagcatag ttcatgttaa ctattttttc acctttttta ccataagctt taactataga
    18781 atcttttaag tatttaacag catcttcttc tggtattatt tcagctaatt taaagaatgc
    18841 agattgcatt atcatattta ttctgtttcc aagacctatt tcttgtccta gtttaacagc
    18901 gttaactgta tagaatttta tatcattttt agctatatat tgcttcatat gagctggtaa
    18961 atgttcttca agtcctgctt ggtcccatat agtgttaagt acaaatgtac cacctttttt
    19021 aagacctttt aataaatcat attgataaac atatgattgt ttatgacagg caatataatc
    19081 agcttcatct attaaataag tagctcttat tggagtatca ccaaatctta agtgagacat
    19141 agttatacca ccagattttt tagagtcata atcaaagtaa gcttgagcat atttttcagt
    19201 atggtcacca attattttga tagcttgttt attagctcca acagtaccgt cagaacctaa
    19261 tccccagaac ttacatctta tagttccttt agaagctatt tttattggct cagatggagt
    19321 taaagaagta ttagttacat catcaactat acctactgta aatccatttt taggttgttc
    19381 tgaaactaag ttatcaaaaa cagtttttat atctgaagga gtagtatctt ttgaacctaa
    19441 tccgtatctt ccacctatta tcataggagc attttctttt ccatagaata catcacgtac
    19501 atctaagtat aatggttcac cagttgaacc tggctcttta gttctatcaa gtacacatat
    19561 tctttcaaca gtagatggca tagcatctaa gaaatgtttc attgagaatg gtctatataa
    19621 atgaacttta actaaaccat atttttctcc cttagcattt aagtaatcta tagtttcttc
    19681 tattgtttct gttactgaac ccatagctat taatacgtat ttagcatctt ctgctccata
    19741 gtaatcaaat aaactatgtt ttctacctgt taaattactc attttttcca tgtatttttc
    19801 aactatacct actatatttt gatagtattt attagaagct tctctagttt ggaaatatat
    19861 atctgggttt tgagcagtac cacgagcaac tggatgattt ggagataaag cattatctct
    19921 aaatgcttga actgcttcaa agtttaataa acttgcataa tcttcatttt ctagtaattc
    19981 aactttttgg atttcatgtg aagttctgaa tccatcaaag aaatgtataa atggtaatct
    20041 accttctatt gcagctaaat gtgcaacagg tgctatatca gctacttctt gaactgaacc
    20101 agaagctaat aatacacatc cagtttgtct agcagccata acgtcttggt gatccccaaa
    20161 tattgataac gcttgagatg ctaaagcacg agcacttaca tggaatactc ctggtaataa
    20221 ctctcctgca actttataca tgttaggtat cattaataat aaaccttgag atgctgtaaa
    20281 agtagaagtt aaagctcctc cttgtaaaga accgtggaat gttcctgatg cacctgcttc
    20341 tgactgcatt tcaacaacat taactgtttg tccaaatata ttttttcttc cttgtgatgc
    20401 ccactcatca actacttcag ccatagttga agatggtgtg attggatata tagctgctac
    20461 atctgtaaac gcataggcaa catgagctgc agctgtattt ccatcaagtg ttttcataaa
    20521 cttagccata atatgtatcc tccttgatag ctacaattgt acttgtttat aacaagtcta
    20581 tttttttata tttacatata atttacacaa caaaactata aacacacata tagtcgcgca
    20641 aatactctat cttctaatat aatactacag attagataaa attcctttga aaattgtaaa
    20701 ttaattacat atttaagtag atttttttta aaattaaata tgttaagttt ttttcataat
    20761 tttgtataca atatataata aattaagtta gatttttcaa acttttttat ctatttgttc
    20821 atattagtat aaaaagtaaa atgcttatcc ttattacatg taaattttta tatatataat
    20881 tttaccatat tacatcatat ttttgtaagt ttttattaca ttttttataa taccccttta
    20941 ttttataaat taatctaatc gattaaattt atcctataga aatttattac atttaaaaat
    21001 atgctagcaa ataaaatatc tactagcata aagtctattt ataatattaa tcaactatta
    21061 attctactaa atctccattt ttaacgcctg ctgcatttcc ctcttccata tcaacatgca
    21121 tttctagatt aaagctgtca ctagctctta ctaatacatt ttcaaatact aatgctcttg
    21181 gtccagatgt tttaactttt actatttgct tatcagttac accaaattta gcagcatctt
    21241 cattgctcat atgtatatgt ctagaagcaa ctataactcc ttctttcatt tcaacttctc
    21301 cagcaggtcc tactaattta acacctggag ttccagctat atcaccagat tcttttattg
    21361 gtgcttttac tcctaatggg aaaccatctg ctaaagatat ttcaacttga gtatgagctc
    21421 tagctggtcc tagtactcta actcctttta aagttccttt tggtcctact aaatccactt
    21481 tttcttcaca ggcatattgc cctggttgag ataatggttt aaatttagtt aactcatgac
    21541 ctgccccaaa taatacgtct atatcagctt gactcaaatg aacatgttta ttagataatg
    21601 ctattggtaa tttcattgaa attccctcct tttaattatt taaattattg caatacaatt
    21661 atacataata ttacctacaa aatcaaatta tattgaatca atatatatct ttaaattttt
    21721 atatattata tctttaaatt cttgattatc ta
//
LOCUS       DAYAKB010000060        21747 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.060, whole genome shotgun sequence.
ACCESSION   DAYAKB010000060 DAYAKB010000000
VERSION     DAYAKB010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21747
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.060"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            281..1879
                     /locus_tag="ACGI3L_002683"
     CDS             281..1879
                     /locus_tag="ACGI3L_002683"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HFG9198381.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(2118..4163)
                     /gene="bclA1"
                     /locus_tag="ACGI3L_002684"
     CDS             complement(2118..4163)
                     /gene="bclA1"
                     /locus_tag="ACGI3L_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HFG9198382.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGNTGVTGSIGPTGVTGPTGNTGEIGPTGATGPTGVTGSIGPTGATGPTGEI
                     GPTGATGATGVTGSIGPTGATGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTG
                     ATGEIGPTGEIGPTGATGPTGVTGSIGPTGATGPTGATGEIGPTGATGPTGNTGVTGE
                     IGPTGATGPTGNTGVTGEIGPTGATGPTGVTGEIGPTGNTGATGSIGPTGVTGPTGAT
                     GSIGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIG
                     NSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTT
                     EPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
     gene            complement(4841..5365)
                     /locus_tag="ACGI3L_002685"
     CDS             complement(4841..5365)
                     /locus_tag="ACGI3L_002685"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9198383.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(5430..6182)
                     /locus_tag="ACGI3L_002686"
     CDS             complement(5430..6182)
                     /locus_tag="ACGI3L_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9198384.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(6213..7511)
                     /locus_tag="ACGI3L_002687"
     CDS             complement(6213..7511)
                     /locus_tag="ACGI3L_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HFG9198385.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(7528..9792)
                     /locus_tag="ACGI3L_002688"
     CDS             complement(7528..9792)
                     /locus_tag="ACGI3L_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HFG9198386.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(10047..10865)
                     /locus_tag="ACGI3L_002689"
     CDS             complement(10047..10865)
                     /locus_tag="ACGI3L_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9198387.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(10858..11556)
                     /gene="cbiQ"
                     /locus_tag="ACGI3L_002690"
     CDS             complement(10858..11556)
                     /gene="cbiQ"
                     /locus_tag="ACGI3L_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HFG9198388.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASINMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(11559..11843)
                     /locus_tag="ACGI3L_002691"
     CDS             complement(11559..11843)
                     /locus_tag="ACGI3L_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9198389.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(11833..12585)
                     /locus_tag="ACGI3L_002692"
     CDS             complement(11833..12585)
                     /locus_tag="ACGI3L_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HFG9198390.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(12767..12959)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(13091..14863)
                     /locus_tag="ACGI3L_002693"
     CDS             complement(13091..14863)
                     /locus_tag="ACGI3L_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HFG9198391.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDVILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(14877..15806)
                     /locus_tag="ACGI3L_002694"
     CDS             complement(14877..15806)
                     /locus_tag="ACGI3L_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9198392.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            16027..16212
                     /locus_tag="ACGI3L_002695"
     CDS             16027..16212
                     /locus_tag="ACGI3L_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9198393.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            16205..16906
                     /locus_tag="ACGI3L_002696"
     CDS             16205..16906
                     /locus_tag="ACGI3L_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198394.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            16908..17831
                     /locus_tag="ACGI3L_002697"
     CDS             16908..17831
                     /locus_tag="ACGI3L_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9198395.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            17988..18911
                     /locus_tag="ACGI3L_002698"
     CDS             17988..18911
                     /locus_tag="ACGI3L_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198396.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            18904..19641
                     /locus_tag="ACGI3L_002699"
     CDS             18904..19641
                     /locus_tag="ACGI3L_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198397.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            19652..20425
                     /locus_tag="ACGI3L_002700"
     CDS             19652..20425
                     /locus_tag="ACGI3L_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198398.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(20966..21574)
                     /locus_tag="ACGI3L_002701"
     CDS             complement(20966..21574)
                     /locus_tag="ACGI3L_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFG9198399.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         6940 a         3757 c         2834 g         8216 t
ORIGIN      
        1 atttataaat ttttaattta ttaacatatt aattaatttt ttcccaggta gatttaatca
       61 atttatttta aataaaagta aatttaattc gatatttgat tgggtaaaag tatatataat
      121 aataattttt atattaaatt tgtagtattt atgtaagaaa taaattttat ataatatttt
      181 ttcactaaat ttttttcttt ttacaacaaa tactcactac cttttgatat aatattttta
      241 tcaattatta ttatattcaa gttttgaaag gagtattaaa atgagtttat tagttttcgg
      301 acataaaaat ccagatacag attcaatatg ttctgcaatt tcattagcac atttaaagaa
      361 caaactagga ataaaagcaa cagcttatgc tttaggagat atcagaaaag aagctaaata
      421 tgccttggat tactttaagg tagatgcacc tgaaatttta gataatgtta gaatacaagt
      481 tagagattta aattatgata aagtagtacc tttaacacca acttcatcta tattagaggc
      541 ttataacctt atggatgaaa aaaatgttaa aacactacct gtaacttatg atgatggaac
      601 ttttgctggt atcattacta tgaaagaaat agctaaaaat ctacttcatc aacactttac
      661 aactatacac acatcactat caaacatttg taaaaacctt aatggtacta ttcttgtgga
      721 ctgtggtgaa gatataaaag gtagagtagt cactttatca tttggaatgg agactctaat
      781 agagacttta aaagaaggag acatagctat tgttggagat agatatgata gtattgaata
      841 tgctattgat acaaaagtta aacttttaat acttactaat catacagaga tttcaaaaga
      901 tttgctagct cttgctaaga taaatggagt gtctgttgtt tctgttgaaa gtgacaatta
      961 taaaacttct aatgtaataa atcaatgtag tttcttagac tctatagaag ctacagaaaa
     1021 tttaattaca ttcaaagaag atgattatat ggatgaaata aaagagatta tgctagaaac
     1081 aaacttcaga tcttatccaa tattagatga tgataataag tttttaggtt tagtttcaaa
     1141 aggtcatcta ttaaacccat ctaaaaagaa tgttgtttta gttgaccata acgaatatgc
     1201 tcaaagtgct gatggaattg aacaagcaaa catagttgaa ataattgacc atcataaact
     1261 tggtggtatt tctactgatg ttcctatgtc atttagagtt atgcctgttg gatgcaatag
     1321 tactataatt tatcaaatgt acaaagaaaa taatgttgag ataccttatg aaatagccgg
     1381 gcttctttta tctgctatat tatcagatac attattattt aagtctccaa caacaactga
     1441 tatagataag aaagcttgtg aagaattaag taaaatagca aaagtagaca tggaaaaata
     1501 cgctatggat atgtttaaat gcggtacttc tttagatgaa tatactatag aagaaatagt
     1561 aaatatggac tttaaagaat ttaatatgag tggacataga gttggtattg gacaagtatt
     1621 taccttagac atagactcta tatttgctaa aaaagatgag tttttatctt atataaattc
     1681 gactgattat gacaaactaa ttcttgcggt tacagatata atcaaagaag gttcttattt
     1741 aatctataaa gcagaagaca gcttaattgc taacgcattt ggtgttgaag gtgttcaagg
     1801 tacatttgca ccaggtgttg tatcaagaaa aaaacaatta gtccctaatt taactactgc
     1861 aatcaaaaat tttaaataat ataaaatttt taaataacga aaactgtctc aaatctatat
     1921 ttgagacagt tttttattat atatatatat attgataata aagttaaata aaaatccata
     1981 aatttaaaat ttttatgaat atattttatt attattgtta ttttattcat tctaaaatag
     2041 gtaaaactca atatataaaa atacttttgt catttaaata aagcctaaat agtttttaag
     2101 attattttag acacgtttta agtcataaca gtatcagcta ttctaaatat cgtcaaagta
     2161 gccgcagttc ctgctgattg cccatttcgt atccctactg ttgtagatga aaaattattt
     2221 attgtaaaag tagtcccacc aaataaaaaa ccagcaaaat atccagaaag tactcctccg
     2281 cctcctggct cagtagtaag ccctgccaaa tcttttcctc ctaaaattgg gaataggata
     2341 gcgaaagaat attgatttat acttgatgaa cctggttgta atgctactga aactgatata
     2401 taatacacac cattttcttg tactgtaaac gtaccatttg catctactgt tatacttgaa
     2461 ctatttccta ttattgtttg ccaacctgtt atagcatctc cattatttag tgtttgtgga
     2521 gatggtgcat ttacgaggaa gttagcaact ggctgagagg aattgcctgt tgctcctgtt
     2581 ggacctgttg ggcctgttac tcctgtcgct cctgttgctc ccgttggtcc tatacttcct
     2641 gtcgctcctg ttggacctgt tactcccgtt ggccctatac ttcctgtcgc tcctgtattt
     2701 cctgttggcc ctatttctcc tgtcactcct gttgggcctg ttgctcccgt tggtcctatt
     2761 tctcctgtca ctcctgtatt tcctgtcgga cccgttgctc ccgttggtcc tatttctcct
     2821 gttactcctg tatttcctgt tggacctgtt gctcccgttg gtcctatttc tcctgtcgct
     2881 cctgttgggc ctgttgctcc cgttggtcct atacttcctg tcactcctgt tgggcctgtt
     2941 gctcctgttg gtcctatttc tcctgttggt cctatttctc ctgtcgctcc cgttggtcct
     3001 atacttcctg tcactcctgt tgggcctgtt gctcccgttg gtcctatttc tcctgttggc
     3061 cctatttctc ctgtcactcc tgtcgctcct gttggacctg ttgctcctgt tggtcctata
     3121 cttcctgtca ctcctgtcgc tcctgttgct cccgttggtc ctatttctcc tgttggtcct
     3181 gttgctcctg ttggtcctat acttcctgtc actcctgttg gacctgttgc tcccgttggt
     3241 cctatttctc ctgtatttcc tgttgggcct gttactcctg ttggtcctat acttcctgtc
     3301 actcccgtat ttcctgtcgg gcctgttgct cccgttggtc ctatacttcc tgtcactccc
     3361 gtatttcctg tcggacctgt tactcctgtt ggtcctatac ttcctgtcgc tcctgtactt
     3421 ccggttgggc ctgttactcc cgttggccct atacttcctg ttgctcctgt atttccggtt
     3481 gggcctgttg gtcctatgct tcctgtcgct cctgtacttc cggttgggcc tgttactccc
     3541 gttggtcctg tacttcctgt cgctcctctt ggtcccattg gacctgtaat tctaattgga
     3601 agacactcac atttaggata acaattatct ataattctat cttcaaatgt tacaagtata
     3661 tacggtttgt tacaacctct actagatgta aattcaagaa tctgataagg gtaatttaaa
     3721 gataaagcta acccataatt aggatattta ttcattgccc atgcttttat agttcccgta
     3781 atatttaaac aaatatagtt ggatgtatca cttatcccaa ctggtaaata tcccctaata
     3841 ttttccatag acactctatc attccatgtt atagttcgta aattataata ttcacttatt
     3901 cttttaattt caatatctac tttttcttta aaaatatgat tcttatttga atcaatatga
     3961 ataaataact ctgcttttaa tatacttttg tcttttaata tatctggtat tctcacttta
     4021 aaaaaagtaa tcaacttttc ttttacaaaa ctatttgaac atttacttcc tattaagcaa
     4081 taatctaaat tactaaagtt tttatctgga tattttttag atataaaagt atcatcattt
     4141 aaataaagta taatatttct catttataat ccctccattt tgggtctata tcatactatg
     4201 tttaaaatac atgcttagtt acaatataat taaaatttat agtattaaat ttttatataa
     4261 taatgctgat ttctacaaaa aaagaacatg tcattagaaa tttctaatag catgttcttt
     4321 ttcattatta tatattacac tttaaattat tccttgactg gcttagctgg tgtaaactaa
     4381 accagtcttt ctaaaatatt aagcactttt ttcttattat gttttttagg atttattgtc
     4441 tatattattg taaaccaaag ttataaaatt gtaaatagaa tatattacca taacaatatc
     4501 tttttataag taaaaattat aaaaaacctt atttttatta aatagaataa ataaaataag
     4561 tttaaaaaat actgaaataa gtgttttcca catattttat atatttattt aatacattat
     4621 tatttaaaaa taaatatata aacaatcata ataaaatttt tttaataaaa ctttattttt
     4681 tagttaaaat catacaatat atagatttcc acaatacaaa taaattaaaa agtgaaatgt
     4741 atttgtctaa aaacataata acatttcact ttatcctcat ttttaagtaa tatatatttt
     4801 taatttttat ttataactaa atctagtttt tatataaatt ttagtttttt tctacatctg
     4861 agtaatctat tccaaaagtt tctacagtaa cagatttcat aacttgtgga gtttgtggct
     4921 tatcagctga atctgttcta actgatgcta tttcatcaac tgtatccata ccttctatca
     4981 ctctaccaaa acctgcatac tgaccatcta agtgtggtga gtttttatgc attatgaaaa
     5041 attgagaacc agctgaatta ggtgccatag ttctagccat tgatatgact cctctttcat
     5101 gttttaaatt gttagtaaat ccattaccac taaattcacc ttttattgag tgacctggac
     5161 cacccattcc tgtaccattt gggcatcctc cttgtatcat aaatcctggt attactctat
     5221 gaaatattat tccattgtaa tatccttcat ttactaatga tacaaagttt ttaactgtat
     5281 ttggagctat atttggatat aactcaattt tgatttcttt tccattttcc atttctatag
     5341 ttactatagg atttttattt tccataattt attaccttcc ttttcattag ttaaattaca
     5401 taattacatt tattatatta tactctaaat taaagtctat caagtatatt ttttcctatt
     5461 tcatatcctt cttgataaat agttttacaa aactcatcat caaagttaag cgtgtcttta
     5521 ggagcaaatt gagtattagg tctaactact attattttat cttcatcata tactttttta
     5581 atatcttctg gcaactcata attatatttt gtggatatta aaataatttt atccacatta
     5641 tccccaatta atggttcaat taatgcactc ctaattaaac ctccatctaa tttgaaacca
     5701 tcataaattc cttcttgcac atctttcaca aattgttctt taaatccaag agttgcgttt
     5761 ggatttgatg gtaacaaccc actgtatgaa atgctgataa tggcttcatt acgaggcatt
     5821 tttgatacgt caacaatctt ttctgatact actttattat caacttcaac ataattaaca
     5881 taaaagttca tttcttctat attactatca tctagttccc ttaggttgtc tatagcagga
     5941 gaattatcca cagtattatt tactattttt acatttccat tctggatatc ttttatattt
     6001 gtccacattt tctccaagtt atcaacattc cctgtgtaca aataatatcc atttattgct
     6061 cctattgatg tccctgaaat cgaataaaat ttatttattc ctccatcata caaggcttta
     6121 actactcctg cttgataagc cccttttgct cctccacctt ctaaacataa tcctaatttc
     6181 atagtctcat ctccaaattg tttatcttat atttatattt caaaaaactt actaaatgtt
     6241 ttatatatac tatagtggtc ctcaacattt cctaattctc ttatagaatg cattgctaaa
     6301 attggacttc ccacatccac agatggtata tctatatgag tagaagatat tggacctata
     6361 gtacttcctc ctctttcatc tgacctatta acaaattctt gatactcaac attagcttct
     6421 ctacatatat ttttataaat agctatagaa tatccatcac tagtatatgc ctgactagca
     6481 tttatcttta taaccggacc ttttcccatt attggtttat tagttgggtc atgcttttct
     6541 ggaatgtttg gatgaatagc atgagctaaa tctgatgata tcataaaaga tgaataaata
     6601 gactcaaaga atccctctct atccttaccc attgatatgc aaattctctc caatatattt
     6661 aacaacatgt ttgaatctgc accttgttta gtagagctac caacttcttc attgtcaaat
     6721 acagccatta catttacacc atgttgacct ttagtattaa caagagcatt caaactagca
     6781 tgtaccattg caagattatc ttgtctccca atagatataa attcatcatt agcccctatt
     6841 aaacttcctt tttcaaattc atataaaaat aaatcaaaat ctataatatc gtccatattt
     6901 acatctaagt tagatgctat ttgctttata agaaaattat ctttttctaa tgtatcattt
     6961 aacatcccaa ctaaaggtaa catatctttt tgcttattat atgagtgacc atcatttata
     7021 cttctattta aatgtattgc tagatttggt attatacaaa ttggcttttt aaagtctata
     7081 agcctttcat ttggttttaa tatactatca ccttttaaaa ctactctacc agctatccca
     7141 agaggtctat ccaaccatgt acttaatatt gctcctccat agcattctgt atttaacttc
     7201 aaataagatt tttcagcttc tatttctgca tttggtttaa tactaaatgt aggagaatct
     7261 gaatgagagc ctattattct aaatccatct ctttctatac cttctgaatt tactacaaaa
     7321 gctactatag ctgataaatt cttagtaaca taatactttc caccaactct tagattccat
     7381 ctttgattca aaactaattc ttcaaatcca tttttatcta agatttcctt agtactctcg
     7441 actgcatgaa aagacgacgg actatcatat atgaagtcta ttaagttttt agcaaagttt
     7501 atactatcca ttcctcattt acctccatta taaaatattt agtgttgtat attctttatt
     7561 tattttttta attccctgtt ggtcaaaagc tatagtaaca tctgtaccaa ttatagaaac
     7621 cactgtccca accccaaatt taggatgatg taccttagaa ccaagtttta tatcatctgg
     7681 attagtttct ttattagaat cttttattgt agcattaact ttatctgcaa ctttagattt
     7741 gcttatagta ctcatatact ttttagtata tttatctaac atattataac ttgctttaga
     7801 atagcttagt tcttttttta ctttgtacaa tctttctata cattcttctg gcagttcttc
     7861 cataaatctt gaagctattg caacatttgt tttaccatat aatgttctct tctctgtcaa
     7921 tgacatatat agctcttctt tagctctagt tataccaaca taacaaagtc ttctctcttc
     7981 ttctatttgt gaatcactca tagattttat agctcttgat ataggaaata acccttcttc
     8041 catacctgtt aaaaacacaa cagggaactc taaacctttg gatgtatgaa ttgtcataag
     8101 cgaaacccta tcattgtctt cttcatcatt tgattcagat gtaagtgcta tacttgttag
     8161 gaatgtctct aagtctttat tttcataagt atcatcatta ctactttcaa actccaaagc
     8221 tatagaaata aattctctca aattatcaat tctgtcttga gcttcttcac ctttgcctgt
     8281 taaatctttt tcatttttat ttcttatctc tacaagctcg tccatatatc ctgtagtatc
     8341 caagactttt tctataagtt tgctaacagg ataaacttct tttatagttc taagagtccc
     8401 tataatatca acaaatccac ttatacttgc ccttgcctta gtagatatat ctgaatttgt
     8461 ttctatatca attaatactg agtatatact ttcctgtttt aagttagctc tatcttcaat
     8521 tttttctata gttctaagcc ctatacctct tctaggaaca tttataatcc tttttataga
     8581 tatatcatct tgtggatttt gaataactct taaatacgcc aacaaatcct ttatttcttt
     8641 tctctcatag aattttgtac caccatatat attgtatgga atttgacttc tatttaaagc
     8701 gtcctctaca ggtcttgcct gtgcatttgc tctataaagt actgcaaaat ccttataagg
     8761 tctattttct tttctagcta tttgtgcaat tgaatcagca atgaaatcag cctcttctat
     8821 ttcactacca gttaattgta tctttataag ttctccttct tttttttcac tccaaagctt
     8881 ttttcttttt ctttctatat tattagatat aactttatta gctgcatcta atataacttg
     8941 tgtagaccta taattttgtt ccaactttac aacatgtaca ttgtcataat ctttctcaaa
     9001 ttcaagtatg tttcttatat ctgcacctct ccatccataa atactttggt catcatctcc
     9061 aacaacacaa atattttgat gttctcttgc taataatttt atcaattcat attgagcttt
     9121 acttgtatct tggtactcat ctaccattat gtatctaaat ctacttctgt aatatgctaa
     9181 cacttcatca ttagccttga aaagttctac agttttaagt attaaatcat caaagtcaag
     9241 tgcactattt ctttttaaac ggtcttgata tagcgcataa atatctgcaa tcttaaccat
     9301 tctattatct gccatattga tatctttaaa ctgctttgga gtataaagtt tgtcttttgc
     9361 tcctgaaatt gcacttataa ctgcttttgg ttcaaacact ttatcactta aatttaattc
     9421 ttttagacag tctttaacca atgtaacttg gtctgctgaa tcataaatta caaaacttct
     9481 attgtaacca atcttattta tatcttttct tagtatacga acacagcaag aatggaatgt
     9541 acttatccac atatccttag tttcaggacc tatattttgt tcaactctct ctctcatttc
     9601 atttgcagct ttgtttgtaa atgttatagc taatatattt ggtgcttgta cacctttatc
     9661 ttctataaga tatgctattc ttgttgttaa taccttagtt ttacctgaac cagcaccagc
     9721 cagtataagt actggacctt cagtcttttc tactgcttct ctttgagcag gatttaatgt
     9781 atctaaattc atatttctcc tcctgttaac agccataaat atattttaat ctaaaatatg
     9841 aattacttca aattataatt atgtattata ttaatagatt atttccaata tattacaatt
     9901 aaataacatt tttccatata atttatttca ttgtttaata aaaaaaataa ccttatgatt
     9961 tggggaatca taaggcacct ttaaggggtc taggttaagg gttattatat ataaatctat
    10021 ttttttaaaa taggtttagg gcttaattat ttatttgtat taagttctct ttccttccaa
    10081 tacttataca aatcttcttc tttcttaaat aagggtaaat tcatatttct atgtactttt
    10141 actaaccatg gggattctag gccagcttgt ataatattat tttcatttat aaacacattt
    10201 tctgcttttc cttcatcaat caaaatcccc ttatccaata catatatgta atcacatatt
    10261 tcatacatta aattcatatc atgactggat attactattt ttatattatt tttatttaat
    10321 ccctttatta tatctacaat agacctagta cttactgggt ctaaaccagc tgtaggttca
    10381 tcaagtaata caatttcatt ttccattgct ataactgatg ctattgccac tctttttttc
    10441 tgtccatagc taagaaaatg tactggcctg tctataaaat ctattccatt aacagctact
    10501 agagctttgt ttattctctc tttaattgtt ttttcatcca taccaatgtt tctcattgca
    10561 aaggctatat catcatatac ttttgaataa aaaatttgtt tttctgggtc ttggaagaca
    10621 atacctacat tttttctaag gttgtataaa cttctcttat catattttaa cttttcttct
    10681 ttaaaaagaa tttctccaga tgtaggcttt aatataccca ttaaattcat aaataatgtt
    10741 gattttcctg aaccatttga acctattata cctataacat ttccctttga aaaatccata
    10801 ttaatgttta atagtgcatt ggtatttttt tcatattgat acgttaaatt atttatttta
    10861 aacatcatta tcccctacta tgtgaaattt accatcatac aattttatgt ctaatgatat
    10921 acacatatca tcataccttg tcataagtct tttgtacagc atacttccaa gaatacctaa
    10981 ggatttatat gaagttttta aatttatata tccaaatctt agctcttgtg acttgtatat
    11041 ttctgaaaat tcttctaaaa atatgaatat aaacctatat attaacattg ataactcgac
    11101 aaaagtgtca ggtaaatgaa gttttttaaa aaagaatatt aattgattaa aaggtgttgt
    11161 aagtatacaa aaatacacac aagtcaaaca agacatcgct ctaaataaca catgaataga
    11221 catgttaata gacgcctttg atattcctac attaaaacta aaaaattcaa aactatataa
    11281 taaatctgct ttattaaaag atatatttac aagagttatt cctatactaa gaaataaaaa
    11341 gtacattggt attctaagta attttaaata attttttaaa tctattccag ccacacaaac
    11401 aaccaaaata ctcattaaaa tcataattcc acttaaaata aatatatttt gtattaccat
    11461 agaagcaatc agaaaaatta ctcctatggc tacttttttg tttggattta ctttactcaa
    11521 tctatttgta tatgcatatt tatcaattat aagcatgatt aacttctctt tcctttttga
    11581 agacctaata tgtatcctat tacaccagcc cctaaagctg cttgtgcaga gaataataaa
    11641 ctttctattt ctccacttgg tggctcatat ggactgctaa accatggttt gtaatttgga
    11701 tttatcttag taatttcact ttcagcttga ccatctgctc ctccatattc agcacctgag
    11761 ttgacaagta atgggaatat aataagagct actactaata aaagtaataa tatgttagtt
    11821 tttgtttttg ttttagcact cattagcttt aactccttta tcattatttt ctagtatgct
    11881 tttttctccg ttttctgtaa ttaaattata tacaattaca gtaagtatac cttctgctat
    11941 tgctattggt atttgagtca taaagaaaat tcctaaaaat ttaattgctg aagccattac
    12001 cccacctgat gggtctggga aagccagtgc taattgtatt gaagttattg tatatgtggc
    12061 taagtctcct attgctgctg caagaaatac tggaatagca ttatttccat cttttttctt
    12121 taaagcctta aatattagga atgatacgat tggccctatt atcgccattg aaaaagcatt
    12181 agctcctaaa gtagttattc ctccatgtgc taataacaat gcttggaata ttaaaactat
    12241 agttccaaga acaaacatta cgcttggtcc aaacattatt gctccaagac ctacaccagt
    12301 aggatgtgaa caacttcctg ttactgaagg tatttttagt gctgataata caaacacaaa
    12361 tgctccacat aaagctaata atactttctt tttagggtct tgctttacta ttttacctat
    12421 tgattttaat ccgaataaga aaaatggtat aaatataact ccccatgcta tagaccattt
    12481 tactggtaag taaccttcca ttatatgcat tgcatttgat gtaactggag ttaaaatgat
    12541 taacataagt gcagctataa cccctaattt aatattctgt ttcatcttag tatccctctc
    12601 tccctttcta ataattaaaa cataataata catgtctgat ttatttaata aaataaaaaa
    12661 gcctaactcg atggttaggc ttctaatttt ccacaatcta aatacaaaca cataaaacaa
    12721 acatatctgt ataattatta taagaaactt tctccatccc cgaagaaatt actttaatat
    12781 tttaggcagg tctcctgact tagcttcatc ctactccttt tccttcccat gagatataaa
    12841 aaatatcatc atagtggcta acaaaagttt cgtctgcatc acagtagcgg gggctgtaaa
    12901 ggaatttaac ctttttccct attaatcttg cttaaagaac ctataatatt atatatttaa
    12961 tttttaaatt attcttaaat cattttctat ataaatcatt gtataccttt tctgtgaaaa
    13021 tttctacatt ttttataaat tttattcatt tttatatttt tatgtatata aattcttttt
    13081 tgtaagttta ttaatttcta attatcttct ttaaatacat tgaaactaca tcagaaaatc
    13141 tagttatatc tcttgaatat ataaaatcat ttccatatat taatctttca gcttcaagtt
    13201 ctgattcttt tcctgtaaat actcctaata ctaatatatt ttgctttcta gcttttctca
    13261 cttcattggc tgtatctctc aaaccaacta tacccctata agccttttct cctcttaatg
    13321 ttctctcact actttttcct atctttacat catttggtct tccatcgctg agaactatca
    13381 ggattttatt ttcttcatct ctatttatta gaccactaca tatagatttt attgccaaac
    13441 catctctatt attaccagca caaaaatatt caaatatatt ttcactattt tttatactat
    13501 catcataatc tttaaatctt tttaatattg tatagtctaa aaaactagaa aatcccatca
    13561 ctctatttgg tatgccaact tctgttagag catttgcaat tatgtaagct tgaattgcca
    13621 catttccctg atttctactt tgagagccac ttgcatccaa taatatatca ataacgtatt
    13681 tccctttttc attttctata tctttataaa atattttatt attattactt ctaccaactc
    13741 tccaagctct attggctaat atagtaccac aatcagaata tactctactt ttagcatttt
    13801 cttctattaa aattcttgac agactttctt ttaatctctt tatttgctgt ctatacattc
    13861 tagcatgttc tctaaatttt cctaaattat tttctttttg tcttgttaca tattttagtt
    13921 gaaatacatt attacactca cttctaagaa ctccatctgt aaagtgtatt ctacaacctt
    13981 catgaacatt tctacaattt tgtgtctcaa tttttttaat ttcaccttta ctcaaataag
    14041 tttttccata ataatgttct atttttgaat atatcttatt tgcagtgtct tcatcaacat
    14101 atataactcg gtctgctgaa ttgctacatt tagaatcatc aaaatcccct acaccttcta
    14161 caagcatgga tgaagatatt gaatctatat cactttcaat aatattttct tcttcatcac
    14221 tataaagttc ttcatacatg aaatcagcaa atgtatcaaa atttacttct acactttcta
    14281 cattattttc atcaataaga ctattttctt ctccatttaa tatgtattca aaataagtta
    14341 aatatataac atctaatgct tttaaaatct ccataatatc ttgattggta tctatatttc
    14401 ttatatcatt aactattctt ctagtcatac tatctaatgc tgggtgcttg tccatactat
    14461 aaagtacaaa tgtgtattta attttatcca taatattatc attgtgtatt ttggtaaaac
    14521 gtgaaacaat atctttataa gcattccttc ttatgtcttc tatccctggc ctgtctttaa
    14581 tgaccttttc ttcaactatt gtatttaata taacttgaat tagacctagt ataacatctt
    14641 tgttgtatcc ttttcttatt ctatttgtaa gatatttttt aactatatcc caatctacat
    14701 actttcttct agcacctgca attattgcga aatatagacc tatttctttt gaagagtaat
    14761 ctttttctga tatatctata ctttcattgt aatcaccagc tattgtccat gataggttat
    14821 tagctctatt ttcaaattca taatcatcat atatccattt cataatctca cctatattaa
    14881 atatgactta ttggaaacac atctatactc tcccatttat taggtattct agttttaatt
    14941 acatctccaa ccatttcttt ctcatataca tcaaaagtct ttcctgtaag tcccatatta
    15001 attgcaagag ttggttttaa tcctcttctt atagtcttaa gagatgccat aagaccacgt
    15061 aaatcaatag ctttactaga tatctctcca ttttgagact tcaattgtaa atctaaaaat
    15121 attcctgcaa agtgtattaa tttttcttca tcagcatctg aaaattcatt ttttaaaatc
    15181 atcattaact tatcttcttc tataggagga atatctatta ccataaatct agataccagt
    15241 gcttcattaa gttcttttgt tcctgcatat tcataattca tagtcccaat aaatcttgtt
    15301 gctggatgta gattgactct ctcataccca ggtacatcaa ttattcttct atagtctaaa
    15361 gctgaatgta ccacaactat agcatcattt tttgccatat taatttcatc aaacacccca
    15421 aaacctccat taatagcaca ctcataaact gagcctcttc taagtttaac ttcattgtct
    15481 ataaatgtat ctgtacctat aagtgttgaa ctgtctgtat ttatatgaaa tgatgtattc
    15541 cactgaggtc tattaaatat ttcccctaga ttatcagcaa gtaagttttt tcctgttgcc
    15601 tttggtcccg ataataatat attttcttct tctaaaatag ctgctataca catagacaag
    15661 atatctttac cataaaaata agttttagac tttgttactc tgtattctaa atctttttct
    15721 aaaccataat aatttctaaa atacagtaca tcttcaataa gtttttcatc taccccttgc
    15781 acccttagat tatctattat atccatattt ttaccccttt tatataaata gtatttgttt
    15841 catttcttat caccatttta gcataaaagg atataagcta aaattgattt tttaatctcc
    15901 ccattttaag taaaaccatg caccatttta tcactacaaa attaagagta ctacttactg
    15961 atatttcttg attttgttcg tctatacgta tataatatat gctgataaat tatgaggaaa
    16021 ggatgattga aatatggatg cccagaagta gcaaaaaaat ggggtatttc tgaaagaaga
    16081 gtacaaaaac tatgtgaaga aagtcgcata ccaggagttt caaaactcgg gtatatgtgg
    16141 ctgataccaa agaacgcaga aaagcctgtt gatggtagaa caaaaagaag aaaggaagta
    16201 caatatgaat agcgttttga ttatagatga tgacaaagaa ctttgtgctc ttatgaaaaa
    16261 atgtgttgag caagaaaatt tatctgctat tactgcacat tgtggtgcag aaggtctaca
    16321 tttggtcgat aaaaatagac acacactctc tcttgtaatt ttggacataa tgatgccaga
    16381 tatagacggt tttcaagttc tgaaaaaaat tagagaaaca agtaatattc cagtaattat
    16441 gcttactgct aaaaatgacg aggatgataa agtttccgga ctacgtttag gtgctgacga
    16501 ttacctaaca aaaccgttca gcataaacga acttatggct cgtgtcaatt ctcttattcg
    16561 tcggtatact atgttaaacc ctgcttttat aacagacaca gattgcataa taataaatgg
    16621 catgattatt gacaagacaa accgaattgt ttctgtcaat aatattcctg ttcaacttac
    16681 aagcaaagaa tttgatttac ttgcttttct ggcttctaat aagggacggg tgtttaccaa
    16741 aaaacagatt tatacacaag tatgggaaga agaatatgct tttgacgata gtaacatcat
    16801 gtctttcatc agtaaattga gaaaaaagat tgaaccagac cccaaccatc cattttatat
    16861 tttgacagtt cgtggtgtcg gttatcgttt taataaggag gcttaacatg aatacaagtg
    16921 tctatctgct tttgatattg gttcttagcc tgattattat agcgtacctt gtttctgtcc
    16981 tgctacgtgt ccgaatacaa cttacactta taaaagatgc tttagaggat ataaaaaatg
    17041 gaaaccttaa tcgacgtatt ttaacagatg aaaacgacat tacaaaacaa atttgctatg
    17101 atattaacga aatagcaatc aatagccaat ttcaacttat tcagcaaaaa caatcagaac
    17161 aagcctacaa acagctaatg acaagtctct cccatgatgt aaaaactcca cttgcttctt
    17221 tggtcggtta tttggaagca gtagaaagta aaattgttgt aggagaggaa aaagacgagt
    17281 atatccatgt tgcgtctaat aaggctcatt acttaaagaa ttttgtagaa aatctatttg
    17341 aatgggtaaa attggattct aaggaacaag tttttcattt tgatattttt gacttgaatg
    17401 aattatcccg taatattata tctgattgga tacctgtttt agaaagcagt cattttgaat
    17461 atgaatttga tataccagaa atagagtact tcttacgtat agacgcaaat gcatataccc
    17521 gtatcattaa taacctatta caaaatatta ttacccatag tagtggcaac aaaatgacat
    17581 tgagaatttt tgaaaacaaa gagcaagctc aaattataat aacagataat gggaaaggta
    17641 tatcttcaga caatctccca catatttttg aaaggttgta ccaatgcgac cattcacgag
    17701 cttcaaaggg aaatggttta ggcttggcga ttgcaaagga acttattaac gctcataagg
    17761 gaaatattac cgccaacagc actcccggta tgggaacaga atttacaata ttgcttccta
    17821 aagccctgta aaagtacgag gctttcttac tctaaaacaa gataaaagca agattatggc
    17881 aaggttttgg caaggttcat gttttataat tctaattgta gttgattttg acgttgtatc
    17941 aactatcttt tgtagaaaca aatttattaa aagtgaggaa attatatatg aatgattttg
    18001 tgattgaaac aaagcaactt acaaaaattt atgggaatca aacagtagtt gacaaagtca
    18061 atctccatgc aaaaaaaggc cgaatatatg gtctgttagg acgcaacgga gctgggaaaa
    18121 ccacaattat gaaaatgatt ttaggattga cttcaatcac gtatggcgag gtagatgtat
    18181 ttggagagaa tattaaggga cgtgaaaaac aagtatatcc ccgtatcggt gcaattatcg
    18241 aaacgccagg attttatcct aatctgacag gaacggagaa cttggagatt tttgcaaaac
    18301 tgcgtggtac agccgcccct aattctgtaa aaagagcatt ggaaattgta ggcttacctt
    18361 ataaaaataa aaagctgttt agtgaatatt cacttggcat gaaacagcga cttggtattg
    18421 ccaacgctat cctgcatgac ccagaactgt tagttttaga tgagccaacc aatggtcttg
    18481 accctattgg tattgcggag atgagaaagt ttattaggga cttgagcgtt gagcatggaa
    18541 agacaattct tatttccagt catattcttt cagaaatctc attgttggct gatgatattg
    18601 gaattatcga ccacggtgtt cttttggaag aaagtagtat gagtgaacta gaaaagaaaa
    18661 acagtaaata tatcctgcta caagtttcag atattccgaa gacatcactt attttagagc
    18721 gtcaatttaa cacgaaggat tattccgttc aagatgacta cacgttacac ctttataaca
    18781 ctaatctgga tatgggtgaa atcaataaag cacttgtaat gcagaatgta actgttatta
    18841 gttctcaact ttgtaatgat actttagagg actactttaa aaaaatcaca ggaggagagg
    18901 gcattgctta aacttattca aacagaattt cttaaactgc gtcgtaggaa acttatttgg
    18961 ctgatgttgt tgtctgctct cattatgccg tttttcgcac tactatactt caattatttt
    19021 ggtaaaacag gtgttgagcc aataaagttt tataaatggt ctgcatttgg ttatacactt
    19081 tggattattt tgcctgttgt tttgggtata ttttgcacca tgcttataca cgaagaaaac
    19141 cagtatgata tgctcaaaca gctttggatt gtacctatta gtaaaatggg atactttttt
    19201 agtaaatttt tcgttgtttt gatttactct atttgtttta tgctgattac agccgttgct
    19261 tctgtgttat ttagtgtact ttctggatat gtcgtattta gctgggcaag cattttatat
    19321 ttgttgaaaa aatgtttaga aattggtgta atcactgctt ttgtaatgtt gccgattttg
    19381 gcaatcgcta catctcaaaa aggatacatt ctcccaattt gtatcacatt ggtatatgcc
    19441 ttttccggtt ttgttataat gacaataaat atgtatttac acccattatc cagtatggga
    19501 gttattatca tgagaaataa agacattcca ggtcttatat tttcacagga aattaatgtc
    19561 ccattagcat ttctttgtat ttgtatttgg agtattgtat cagtattgtt tgcaaacact
    19621 gcactaggaa gaagaaagtg aggtgtagat aatgtggaaa ttactttggg ctgaatgtca
    19681 aaaaattcgt cgttcaaaaa ttgtttggat tacagttttt gcatccatta tgatagcagt
    19741 catagttttt gcaggagggc aggatgtata taatgaccca gatttacatt atggcttaaa
    19801 gagcgtttat gacggttcac ggtatataga caatgcaggt tggtatatgg acgcagtaca
    19861 accttggtca actttttttg ttcttcctgc tgtcattgcc ctattaggaa gctatattat
    19921 ttgtcgtgaa gaagaggagg acactattaa atccctgcgt cttattccca taaatgaaac
    19981 aaaattaacc atagcaaaaa tgattattac ttttatattc agtatacttc tttatttgtt
    20041 actctttact ataacatttt tgactgaatc cgttttacat ttttccgatt tatcgacaaa
    20101 actggtttta agttgcatga aagagtattt tcttgatggc ataggtgtat tctttgcaat
    20161 ttctcccatt attgccttgg tatcgcgcat gaaaaaagga tattggcttg cattagtatt
    20221 cacagaagtt tattctattg ctggactatt tgcgggtatg tcaaatgtct tacaaacctt
    20281 ttttcctatt gcggcaatat ttaatatttc tggatactat ataactactg gagaaaaaat
    20341 tatggggagt atcataagtt tattactttg tgcctgcctt tctgcattta tacttaaagg
    20401 gctaaaacac aatgaaaaaa attgaaatag gtatatcaaa atgaaaaaga taaaaaaact
    20461 gattattcta attgtattct tgtttctttt tggcatgtta cactgttata ctgaatggaa
    20521 attcaacaat aacccaccta aaggggtaat agaaagaata aatgaatgga ctgataagat
    20581 tggactggat tagtaactta tgttaattat agtgaatgta atattagcaa gttattgttt
    20641 cgtattttaa tactataact ttaaatattt ggttttaatc ttccaaacga atataaaaaa
    20701 actgtcacag aggcaacata tttttgaata tttataaagt ggtagttttg attttcaaag
    20761 ctgccgcctt ttcttctata taagcaaact tatcctcaac aaagtgtaaa acatggtaca
    20821 ttttaagaaa aaagtaccac agacacaagc aataaaagaa acgccgagaa cctacaaaaa
    20881 cgtagtgctt atgcagattt acgacgcctt ctattttctc aaccgtctta atgaccttgt
    20941 acaaaagaaa tttttctaat attttttata atcttatctt gtgatgtttt ttatgtataa
    21001 atgacttaat aacaaatcca ataaaaatta tggatattgg tataattaga acgaggaatt
    21061 tataatcatt ataatgtgac attattctta cccaactctc agaaaaaata tatcctatac
    21121 tgattaatga agtattccat atggttattc ccacgataga tgatattaca aaagttataa
    21181 tattttgacc tgctatacct gctataaaag atatgtatgt tctacataaa gggattaatc
    21241 tacatacaca aacagaaata gaagagtatt tgttaaaata atcttgagat gcaaatattc
    21301 ctttctttgc ctttggacat atctctatta ttttatttat gatagattta cctccccaat
    21361 ttcccactgt ataacaaaat atcgaaccaa gtatacctgc aattatactt aaaattaaaa
    21421 ttgtcagaaa tccaaaatga tttcttgcag caattgctcc acataaaggt aaaacaactt
    21481 cgctaggtaa tggaaaacaa gcatactcaa tcataattaa tacaaataca gagattaatc
    21541 catattgtaa aataaaacta ttgattacag acacttactt atctatctcc tttcttattt
    21601 aaaggtttta agggtacatg ttctaaggat tctcacccta tatttaaaga atcaatctct
    21661 ttaaactatt atatgtattt acacaaagca tttataacat actttaaaaa tagtacctta
    21721 aaataagaaa cttaataaat aaaaaaa
//
LOCUS       DAYAKB010000061        20909 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.061, whole genome shotgun sequence.
ACCESSION   DAYAKB010000061 DAYAKB010000000
VERSION     DAYAKB010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.061"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="ACGI3L_002702"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="ACGI3L_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFG9198400.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="ACGI3L_002703"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="ACGI3L_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFG9198401.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="ACGI3L_002704"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="ACGI3L_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFG9198402.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="ACGI3L_002705"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="ACGI3L_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFG9198403.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="ACGI3L_002706"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="ACGI3L_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFG9198404.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="ACGI3L_002707"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="ACGI3L_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFG9198405.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="ACGI3L_002708"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="ACGI3L_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFG9198406.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="ACGI3L_002709"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="ACGI3L_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFG9198407.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="ACGI3L_002710"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="ACGI3L_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFG9198408.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="ACGI3L_002711"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="ACGI3L_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFG9198409.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="ACGI3L_002712"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="ACGI3L_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFG9198410.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="ACGI3L_002713"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="ACGI3L_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFG9198411.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="ACGI3L_002714"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="ACGI3L_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFG9198412.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="ACGI3L_002715"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="ACGI3L_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFG9198413.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="ACGI3L_002716"
     CDS             6989..7174
                     /locus_tag="ACGI3L_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFG9198414.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="ACGI3L_002717"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="ACGI3L_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003241998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFG9198415.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="ACGI3L_002718"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="ACGI3L_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFG9198416.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="ACGI3L_002719"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="ACGI3L_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFG9198417.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="ACGI3L_002720"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="ACGI3L_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFG9198418.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="ACGI3L_002721"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="ACGI3L_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFG9198419.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="ACGI3L_002722"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="ACGI3L_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFG9198420.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="ACGI3L_002723"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="ACGI3L_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFG9198421.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="ACGI3L_002724"
     CDS             11117..11767
                     /locus_tag="ACGI3L_002724"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFG9198422.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="ACGI3L_002725"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="ACGI3L_002725"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFG9198423.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="ACGI3L_002726"
     CDS             12536..12805
                     /locus_tag="ACGI3L_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HFG9198424.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="ACGI3L_002727"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="ACGI3L_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017185218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFG9198425.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="ACGI3L_002728"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="ACGI3L_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFG9198426.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="ACGI3L_002729"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="ACGI3L_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFG9198427.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="ACGI3L_002730"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="ACGI3L_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020449874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFG9198428.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="ACGI3L_002731"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="ACGI3L_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFG9198429.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="ACGI3L_002732"
     CDS             14901..15848
                     /locus_tag="ACGI3L_002732"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFG9198430.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="ACGI3L_002733"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="ACGI3L_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFG9198431.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="ACGI3L_002734"
     CDS             16330..17163
                     /locus_tag="ACGI3L_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HFG9198432.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="ACGI3L_002735"
     CDS             17151..18017
                     /locus_tag="ACGI3L_002735"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HFG9198433.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="ACGI3L_002736"
     CDS             18011..18814
                     /locus_tag="ACGI3L_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFG9198434.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="ACGI3L_002737"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="ACGI3L_002737"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFG9198435.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="ACGI3L_002738"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="ACGI3L_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFG9198436.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="ACGI3L_002739"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="ACGI3L_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFG9198437.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8357 a         2455 c         4337 g         5760 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaaagagggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctactttat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc tagatgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tatcccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtattaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccta ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatatttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 atatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tatagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacatat gctaataaca tttaaatttt atttttataa
    20761 tattgtaatt taaaagttta tataaggtta tatattttaa gatattattt aacaatataa
    20821 attctgaata tacgttatca aaatttataa tataaactaa gtataattta ttgtatagta
    20881 ttgaatgtta gataaacata gtgaattaa
//
LOCUS       DAYAKB010000062        20785 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.062, whole genome shotgun sequence.
ACCESSION   DAYAKB010000062 DAYAKB010000000
VERSION     DAYAKB010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.062"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            364..1200
                     /locus_tag="ACGI3L_002740"
     CDS             364..1200
                     /locus_tag="ACGI3L_002740"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008833 - deoxyribonuclease IV
                     (phage-T4-induced) activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFG9198438.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            1484..2479
                     /locus_tag="ACGI3L_002741"
     CDS             1484..2479
                     /locus_tag="ACGI3L_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFG9198439.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKEYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(2736..3140)
                     /locus_tag="ACGI3L_002742"
     CDS             complement(2736..3140)
                     /locus_tag="ACGI3L_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFG9198440.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            4162..5076
                     /gene="queG"
                     /locus_tag="ACGI3L_002743"
     CDS             4162..5076
                     /gene="queG"
                     /locus_tag="ACGI3L_002743"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFG9198441.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLNYDEIQNISNKEFKR
                     KYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            5182..7419
                     /locus_tag="ACGI3L_002744"
     CDS             5182..7419
                     /locus_tag="ACGI3L_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9198442.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            7617..8786
                     /gene="nth"
                     /locus_tag="ACGI3L_002745"
     CDS             7617..8786
                     /gene="nth"
                     /locus_tag="ACGI3L_002745"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFG9198443.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKEEINKKGMNKKDIIEKEEINKKGMNKKDIIEKEEINE
                     KGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKGETEKKTKKSSSNKATQ
                     KTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGTAFELLIATILSAQC
                     TDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLCELY
                     DGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPNPQK
                     TEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK"
     gene            8980..9450
                     /gene="trmL"
                     /locus_tag="ACGI3L_002746"
     CDS             8980..9450
                     /gene="trmL"
                     /locus_tag="ACGI3L_002746"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFG9198444.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            9486..10334
                     /locus_tag="ACGI3L_002747"
     CDS             9486..10334
                     /locus_tag="ACGI3L_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFG9198445.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            10622..11626
                     /locus_tag="ACGI3L_002748"
     CDS             10622..11626
                     /locus_tag="ACGI3L_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9198446.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            11752..12864
                     /locus_tag="ACGI3L_002749"
     CDS             11752..12864
                     /locus_tag="ACGI3L_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9198447.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLLTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDFIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            13354..14115
                     /locus_tag="ACGI3L_002750"
     CDS             13354..14115
                     /locus_tag="ACGI3L_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6873 family GME fold protein"
                     /protein_id="HFG9198448.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            14118..14936
                     /locus_tag="ACGI3L_002751"
     CDS             14118..14936
                     /locus_tag="ACGI3L_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HFG9198449.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            15116..15718
                     /locus_tag="ACGI3L_002752"
     CDS             15116..15718
                     /locus_tag="ACGI3L_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HFG9198450.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    16330..16568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16632..18551
                     /gene="thrS"
                     /locus_tag="ACGI3L_002753"
     CDS             16632..18551
                     /gene="thrS"
                     /locus_tag="ACGI3L_002753"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFG9198451.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            19319..20410
                     /locus_tag="ACGI3L_002754"
     CDS             19319..20410
                     /locus_tag="ACGI3L_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFG9198452.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
BASE COUNT         8563 a         1903 c         3766 g         6553 t
ORIGIN      
        1 ttttatacct attgtatttg taaataatat gtatagtgta agatgtatac actatctaag
       61 aagtgcttag ataatataca aagtatgtaa gattataata tttgaaattg attaaaatgg
      121 gtataattaa agtgtaaata ttaaaattaa aaattaatat aaattaaatc aatgctagaa
      181 atatgttaaa agaggaatga gattagttgg gatagaacat cccttagagc ttacgaattt
      241 ttagtgaaaa agtactatca aataggaatc tccatcttca tatgttggct aaatgtagtt
      301 aaggtggagt agttcaaaat taaaattgag tacaagtagt agtacaaata aaaggagatt
      361 aatatgatta aattaggaac acatctttca atagcaaaag gatttgctaa tgcggctgag
      421 acagctgtat atattggtgc aaatacattt caatttttta gtagaaatcc aagaggagga
      481 aatgctaaag aatttgatga aaaagatata attaaatttc aagaaattag aaaagaaaat
      541 aattttgcac cactgcttgc acatgcacca tatactatga atctgggtgg tacaaaggat
      601 gatgtatacg aatttgcaac aagggtgata gatgaggata taagaaggat ggactcatta
      661 ggaattgaat acatgtgttt tcatcctgga agtcatgtag gtggtggtgt agattttggc
      721 atagatagaa tagtaaaagg attgaacaat gccataaagg gtgatgaaaa tataactata
      781 cttcttgaaa ctatgtcggg aaagggaact gaaataggtt ttaaatttga gcaattaaaa
      841 agtataatag acaaaattga gcataaagaa aaaataggtg tgtgtcttga tacatgtcat
      901 attttttcag ctggttatga tatagtgaat gatttagatg gggttttgga agaatttgat
      961 aaggttatag gcatagaaag attgaaaact gtccatctaa atgatagtat gatgccattt
     1021 ggagacaaaa aagacagaca tgctcctata ggggaaggaa agataggatt aaaagcatta
     1081 attgatttta tggaacatcc tagtctaaaa catttaccat ttttcttaga aactcctttt
     1141 gatgatgaag gtcacaagag agagcttaaa atgataaaag aaatactatc tagtaaataa
     1201 acctttatta aaaatatgtg aaatactcca ccctcaacat aattagggtg gagatacaat
     1261 catgaaatgt gataatttaa attaatggat aggaataacg aaaattgtat acaaattaac
     1321 tgggtataaa gtatgattat attatgaata gactgatata aaatataatt atattatgaa
     1381 tagtatgtaa atacattgca aagattctca taatttgttg tataattaaa ggtgacatat
     1441 ttatattata taaaaaatta ttaaaagtta ggtggggaaa gatatgagaa atttaggcaa
     1501 tactaacatg aaaataaaga gagttggctt tgggggcatt ccaatacaaa ggattactca
     1561 agatgatact aacttagtta taaatgagtt agaaaaacaa ggaataaact ttattgacag
     1621 tgcaagaggg tatacaataa gtgaggaagc aatcggaatt gccattgaag gaaaaagaga
     1681 taaatttttc ttagctacta aaagtatgtc cagagattat gattcaatga agagagatgt
     1741 tgaaataagt ttaaataatt ttaaaactga ttttatagat ttatatcaat tccataatgt
     1801 taaagaagag gagtatgata atctttttaa agataaaatg gcttatagtg cccttttaga
     1861 ggcaaaggag caaggtaaga taaaacatat tggtataact agtcacaatt taaatactat
     1921 agaaaaagct atagaagatg gaaaatttga cactatacaa ttcccttata atatagttga
     1981 aggacaagca gatgaagtgt ttaaaaaagc tcatgaaaaa ggaattggga taatagtaat
     2041 gaaaccttta gctggaggtg ctttagacaa tgcaacactg gctattaaat atatactatc
     2101 taaagagtac atagatgtag ttataccagg tatggagagt gttgaacagg ttagacaaaa
     2161 tgtcgctgta cttgaaaatc ttgtgctaga tgaaaaagat aataaggaaa ttgaagaaat
     2221 aagaaattct ttaggtaaaa aattctgtag aagatgcgaa tattgtatgc cttgtgctgt
     2281 aggaataaat ataccattga gttttttatg tgaaggttat tatactagat atggattaaa
     2341 agagtgggct aaagaaaaat atgaggttat ggatgttaaa cctactgagt gtattgactg
     2401 tgggctttgc gagagtagat gtccatatga acttcctata agagaaatgc ttaagactgt
     2461 tgttgaaaag ctaggataga ttttatttat tgaaatcggt gtattaaatt tactccgatt
     2521 tctttttatt agatgtggtc ttatatacaa atattaaatt tacatagtta tagctattat
     2581 ataaatttaa tatttgttta atacttatta aatatttact taatgctttt taaaaacatt
     2641 tgtttgagta tagacataac acaattatta ttgttgtatt agtatagttt caaatactgg
     2701 agtatcaata taatgtcgaa taacacataa aatctttatt tttcaaaaat attataggat
     2761 atatcgtatt tagatactgg ataaagttca atttcaaccc tagggttatc tttatctata
     2821 aaatcaaata aaagtactgg cttaagttgt ttatcatttt ttattattcc acttttttca
     2881 ataccatcac aaatactttt tggataatta tgtaaatccc ccattctctt atttgggaag
     2941 aataatttca agactgttat tagattttct tcgacagttt ccccttgata ctgttggttt
     3001 ataaaacctg caatcatgtt ttcgtatgca agatacttag aatattttcc ctttgaaggc
     3061 atccatgctt gaccatttat gttatgaagc ttaaaattag atttactaat aggtctacct
     3121 ggaattgtta ttttaatcaa atttttcacc atccttatac agtatttatt ataatctgta
     3181 tatgatttaa aagcaaattg ttatttaaag tgtttttaca gagctttttt gtaaaatttt
     3241 ccactttaga tgtagtaata taagataagt attttgctta caaattttaa aatttgatat
     3301 atgatggaca tattcatatt agtctattat aagaccttca taatattaat aagtatagtt
     3361 tagtaaagag agtaaaaaga aatccatata agtcaagtaa agatttaata aatggcaatg
     3421 taaatgggat attaattata agaaaaaatc aatctttttg cttaactata gaaagaatgt
     3481 caaaatataa ctaatgatat ttgaagtttt agagtttata ttaaaaggta agaaggttaa
     3541 gtgggtaaaa aaggttgaat agattaaaaa ggctaagtat ctaaaagagt taagtaggta
     3601 aaaaagttaa ataagtaaat gaaaaaggct aagtatctaa aagagttagt agttaaataa
     3661 gtaaatgaaa aaggctaagt atataaagga gttagtagat aaaaaaatta aatagataaa
     3721 aagattaagt atctaaaagc gttagtagat aaaaaaatta aataaataaa aaagactaag
     3781 tattcaaaag agttagtagg taaaataatt aaatagataa aaagactaat tatttaaagg
     3841 agttaagtag ataaaaaagt taaataagta aatgaaaaag acgaagtatc taaaagagtt
     3901 agtaaataaa aaagatgaag tatctaaaag agttagtagg taaaaaacta aatagataaa
     3961 aagattaagt atctaaaagc gttagtaggt aaaaaattaa ataggtaaaa agacgaagta
     4021 tctaaaagat ttaagtaggt aagaaaattg aatagctaaa aagattaagt atttaaaaga
     4081 gttagtagct agaaaaggtt aaaaagacta aaaaaattaa ataaatttaa aaagtcaatt
     4141 agattaaaaa ggaataattt tatggataat aaggaattaa aagcattttg taatttaata
     4201 ggattaaact gtgtaggagt agcaggggta gataagtatg ataatttaga aaagatactt
     4261 aaggacagac aacaaaaagg ttatttaact ggtatggaag aaccaataat tgagaacaga
     4321 attaacccaa gacatataat gaaggatgct aactctataa tagtctgtgc atttccatat
     4381 catataaata gacaagaaaa gaataaaaat tcaaatttat caaaatattg tcatggaaag
     4441 gattatcaca ttgtagtaaa ggacttttta caacaaattt gtgattatat ttctaaaaca
     4501 gtaacagatt ttaaatacaa gttatttgct gataatggac cattagttga caggtattta
     4561 gcttatttat caggaatagg atattttgga ataaataata atatcataac tgatgaatat
     4621 ggttcttacg tatttatagg gtatatagta aataattata aatttgaaga agataaacca
     4681 ctagaaaaaa gttgttttaa atgtggaaag tgtgtaaaat attgtccggg aaatgctata
     4741 ttgggaaatt atgatatgaa ccccaaaaaa tgtttatcat atataactca aaaaaaagga
     4801 gatttgtcag agaaagaaaa agttgtttta aagaatggca aaaaggtatt tggatgcgat
     4861 atttgtcaag aagtatgtcc acataatgtt gaaataccaa caactcatat tttggaattt
     4921 aaagaaaata taatagatta tttgaattat gatgagatac aaaatatttc aaataaagaa
     4981 tttaaaagga aatatggaga tagagctttt agctggagag gaagaaatat aataaagaga
     5041 aatatggaaa taattttaga taagtatgat gactaataat aagagtctgt ttcatatact
     5101 ttaatgtgta tttactttaa cacttgttgt gtaaaagtca tattatatca ttaaagttaa
     5161 atatggggag gtgggggaat attgaaatat aataatacat ctgaaataaa tccactagat
     5221 tatatattgg gtcaagaaag agctgtagaa gctatggaat tagggttgaa aataaataat
     5281 ccagcgtaca acatatatat agctggtgaa cctggaactg gtaaaagtac ttatgcctta
     5341 aaggttttaa atgagtatgc atccaaaaaa aatacgcata aagattggtg ttatatatat
     5401 aattttgaaa accctagaga gcctattata gttgaattag aaaaggggtt tggaagagaa
     5461 cttaagaaag atatggagaa attaattgaa agtcttttag aagattttaa aaatgcgttt
     5521 gaaagtgaaa attttgaaat agaaaaaaat aaacttctgg atgaatatga aatagaaaaa
     5581 gatatgcttt tgaagcaaat taaaaaatat ggagaagaaa aaggatttaa attaaaacag
     5641 agtaaaatgg gaatagtttt tatccctttg aaagaagagg aagatgaaag tgatgagtct
     5701 gatgaagagt tttacaaagc taaaagagaa ctagaaaata tggcgataca ggtcgtatat
     5761 aaaattagaa acttagaaga aatagctgaa aaagcagtgt tagagcttga agaagagata
     5821 gctaaacttg tagtagaacc tcatatcaag agattgtgtg aaaaatatga aaattatgat
     5881 aagattcaaa cttatctgga aaatataaag aaagatataa tagaatatat gtatttattc
     5941 tatttagatg aagaggagtt aaaagataag tatgataaag agcattttat taaatataaa
     6001 attaacctat ttgtagacaa tggaagctca aagaataaag aatcagcacc tgttgtagta
     6061 gagataaacc caagtccagc aaatctattt ggaaaggcag agtatgatta tgcaaatgga
     6121 aatataaaga ctgatttcac aaaactatta tcaggagcat ttcatagggc taatggtggt
     6181 tatttagtac tttatgcaga ccaattacta aaatatacaa tgtcttggga aattcttaaa
     6241 aagactttgc agactaaaaa agtaatattg gaaacacaaa cagcaattaa accagaaaat
     6301 atgccattgg atgttaaatt agtactgatt ggaagccact atatatatga tattttatat
     6361 agatatgatg aagattttga aaaatatttt aaagtatttg tagactttga tagtgaaatg
     6421 gataaaaatg aagataatga agaaggaata gcaagattta tagcatacca atgtgataag
     6481 aataatttaa ggcattttac taaatcagca gttgaagagg ttattaaatt tagcactaga
     6541 ttatctggtg atttagaaaa attatcaact aagtttaata aaataatgga agttgtaata
     6601 gaaggaagtg cttatgcaga gtttagaaat tcggagtata cagagcagtg tgatgttaaa
     6661 aaagcaataa gtgaaaagag aaaaagaatc aatagagtgg aaacacatat ggatgaatca
     6721 attgaaaatg gatttactct aatagaaaca gagggaagaa aagtaggagt gataaatggt
     6781 ttgtcagtct taagtacagg agaatactct tttggtagag cttcaaggat tacagcgacc
     6841 actagcccag gaagtaaagg catagtaaat atagaaagag aagtaaatat gagtggctct
     6901 atacataaca aaggagtact tatattaggt ggctatcttt ctgagaattt tgcacaggat
     6961 ttactattgt cactaaatgc atatgtttgt tttgaacaaa attatggtgg aatagatgga
     7021 gatagtgcat cttctgcaga attatatgta ctattatcat ctcttagtgg agtatcaatt
     7081 aaacaaaata ttgctgttac aggttctata aatcaaaagg gtgatataca agtagttggt
     7141 ggtataagtg aaaagataga aggattttat tctatatgta aaactaaagg gttaaatggt
     7201 gagcaaggcg tcataattcc tagaaaaaat caaagaaatc tcgttttatc agatgaagtt
     7261 aatgatgcag tgcgagatgg aaaatttaag atatatactg ttgaaagagt agaagaggct
     7321 atagagatat tgacagatgt taaatttgaa gaaataaaga aattggtaaa agaaaaatta
     7381 atatctttca gcaagataca aactgtgtca aaagaataag tttattatag aatttaatgg
     7441 gtatttatgt ataataaaaa gcaagaactt taataggttt ttgctttttt tgtaaatata
     7501 tataaattaa attcttattt tgtatgtttt atatattgat gtttattttt ttgttgatat
     7561 gattaaacta tttataaata gcgttttata aattggtatt ttgaaggggg ataattatga
     7621 aaaatgtaaa tctaaaagag ataaatgaaa aagatgtaat tttggaagaa gagataaata
     7681 aaaaaggaat ggataagaaa aatataattg agaaggaaga gataaataaa aaaggaatag
     7741 ataagaaaga tataattgag aaggaagaga taaataaaaa aggaatagat aagaaagata
     7801 taattgagaa ggaagagata aataaaaaag gaatgaataa gaaagatata attgagaagg
     7861 aagagataaa taaaaaagga atgaataaga aagatataat tgagaaggaa gagataaatg
     7921 aaaaaggaat agataaaatg attggtaaaa aagatgagat aattgatgag aaagatatag
     7981 agaattttat ggatattgaa gaagataaaa aaagtatcaa agtaagtaaa aaaagtacta
     8041 aaaaaggtga aacggagaaa aaaacaaaga agagtagttc taataaggct acacaaaaaa
     8101 caagtaaaga aactaaaagt aagtctaaaa ttaaaaatga gtcagcaaat gaaaaagacg
     8161 taaataagat tttagacgag ttagaaaaat tgtatccaga tgctaaatgt gagttaaatt
     8221 atgggacagc ctttgaactt ttaatagcaa ctattttatc agcacaatgt actgatgtaa
     8281 gagtgaataa agttacttca gagttgttta aaaagtacaa cacagctaga gactttgcta
     8341 atttgagcat tgaagaaatt agtaaagaga taaagagttg tggtctttac aaaagcaagt
     8401 ctcaaaaaat aaaggataca tctgaacagc tatgtgaatt atatgatggt gaagtacctg
     8461 atagcttaga aaagcttata aaattacctg gtgttggaag aaaaacggca ggggttgtac
     8521 ttagtaacgc ttttaatcat ccagcaatag ctgtagatac tcatgtattt agagttagca
     8581 atagaatagg aatagtggac gagccaaatc ctcaaaaaac agaatttgca cttatggaag
     8641 ctataccaaa agaaagatgg tcacactcac atcatgtatt aatttttcat ggaagaagaa
     8701 tgtgtaaagc tagaaatcca gaatgtgcaa gttgcccaat aaaagaagat tgtaattatt
     8761 ataaagaact taatgaaacg aaataacttt tagaaagtaa gttgtacaag agggattttc
     8821 tgatataata atacttgtga aaatgttaga taaaaaacta ttatatacat gaaataaaaa
     8881 ttattattaa cattatttta tataatagta taatattatt gttattctgt ttataaaata
     8941 aaatttgata aataaaagcg atacttaggg aggattaaaa tgtcattaaa tatagtatta
     9001 gtagaaccag aaatacctca aaatacagga aatataataa gaacctgtgc agcaacaggt
     9061 tcaactttac atttagtaaa accactgggt ttttcattgg atgataaaca cctaaaaaga
     9121 tgtgggcttg actattggga tatagctgat atacaatatt acgatagctt tgaagaatta
     9181 caagaaaagt atccaaatag taaatacttt ttttctacaa caaaggctaa acagtcacat
     9241 tcagatgtga aatatgaaga aaattgtttt atagtatttg ggaaagaaac aaagggatta
     9301 ccagaacctt tgttgaaagc aaatatggat acttgtatta gagtgcctat gttggatgtt
     9361 gaaaaagcta ggtcattaaa tttatcaaat tcagttgcta ttgtagtgta cgaggcttta
     9421 agacaaatag gatacccaaa tatgaggtag tttcaacaag cctaaatgag aaaggagcat
     9481 acttaatgaa aaatctaaag ataatctgtg acagtttatc ggacgtgcca aaagatttgt
     9541 tagataaata tgatatagat atagtttcat taacagttat actggaggaa agagaataca
     9601 aggatagaat tgatatatct ggagatgaat tttataaaag gcttagagaa gaaaatgtat
     9661 atccaaaaac ttctcaagct acttatgccc aatttaagga aatttttgag aaatatacaa
     9721 atgaggatag agagatactt tatatagcag ggtctgccac agctacaggt acgtatcaaa
     9781 gtgctgtaat ggcaaagaat gatgtagatg gtaaaatata tacatatgac tctaacttgc
     9841 tttgtatggg aactggttta cttgtaataa aagcaggaga acttgcaagt gaaggaaagt
     9901 ctgttgctga aatattgcct gttttggatg aattaaaaga gaaggctttt gttatatttt
     9961 cagtagatac attggaatat ttacaaaagg gaggtagaat atcatctact aaggcagcaa
    10021 taggaagtat attaaatata aaaccgattc ttgaaataag agatggatta gtttcgcaaa
    10081 tatctcaagt aagaggaaag aagaatgtaa tttctaagat gatggaattg ataaaatcaa
    10141 attgtggtga tgatttatca gaccaaattg tgtatatagg atatagtgat gattttaagg
    10201 aaaaagaaca attatctaag gttatgcaag atgaattaag acctaaagaa attagatttt
    10261 tccaaattgg tgtgtgtata ggtgcacatg ctggtcctgg tgttactggt atcatatgct
    10321 taaaaaataa ataatatatt tttggatgac attatttatt tttttattaa attaggatag
    10381 aatattaatt gttgagatgt taaattggat ttattttgga tgaaattaag tgttgatata
    10441 ttagatttag tttgtaggga agtgtgtaaa tagataagaa tctattgcac acttttttat
    10501 agtaagattt attaaaaaaa tttcaaaatg tacttgtaaa ttgtatataa aaaaattata
    10561 aataggatgt aaaagtaaat aggatataaa aatatcgtaa atgtatgagg agtgaaattt
    10621 aatgcgtttc aaaagaatat tgatattgat gttaactgta gcaatgatag ctggaatgtt
    10681 ggttgggtgt gctaataacc caagtaataa tcctagctct agcaaagata ataaaagtga
    10741 tataagcgat aaaagtaatt caaaaaaatc tgtatcaatg atactagata ttgaaggaac
    10801 aaataatgaa gctatgaata attcagcttt attagcatta aacaatgctc aaaagaaact
    10861 taatatagat acaaacaaag tggaatcaga tgattcctca actttttcta atagtataga
    10921 tattttatgt aatgacaatt acgatttaat tatagctgta ggagctagat ttgcaaaacc
    10981 attggagatg gtagccaaga aatatccaaa gcaacaattt gcaattatag actatgagta
    11041 tgacaagcaa ccttctaata taacttcaat ttcttatgaa gataataaat ctggatacct
    11101 agctggatta attgctggaa aaatgactga aagcgataag gttggtttta taggaggaac
    11161 aaagagttct agtagagata aatttgaatc aggttttaga gagggtgtta aattttctaa
    11221 tagtagtata aaggatattt cagttgagta tgcagatgtt tttaaagata gcaaatcagt
    11281 agaatctata gctaaaaaaa tgatggataa tggagtggat attatttttt ctactactga
    11341 agatgattca aaagctgtaa tagatgcagt aagggcaaaa aataaaaaag ttatagcaac
    11401 gaataaagac caacatgagt tagctccaga aaatgttata agttctattg taaaagattt
    11461 tgagaatcct acttataatc tgatacaaag ttttgtaaaa ggaaattata aaggcggaaa
    11521 ggttatagaa aacacagtta agtctggaag tactggactt gcccaaaata gttctcaaaa
    11581 tattcctcca gatgtgttag aatatgttaa taagaacaat aaataatcta ctataatatc
    11641 caagaatact tatgagttta gttatgaggt gaattggatg ttataataga catatataga
    11701 aagacatatg cagaggtagg tcagacctat ctaaatcagg gagtgaattt tgtgaaaata
    11761 aaaaggatat tgatggcttg ctttgtagta gtttttacaa tttttatatt agctatatgt
    11821 aattttgatt ttgggtttga taaagtaaat aagaataatt ctaatataga tagtgctaaa
    11881 tcgaaacaga gtgagtctaa aagtttgcta acttcagcag aaaaggataa atcaaatagt
    11941 aaaagtaaga ataaagaaga tgacacagaa gatgattcat atgtaagaaa aactattgga
    12001 gtattgttag ataccgaaaa cttaaataac gaatcatata ataacaatgt actatcagcc
    12061 ttaaaaaggg ctgacgaaga ttttgatgtt aggataaaac ttgaaaaacc aaagacttct
    12121 aaaagtttta aagagagtat agaaaaactg cataagtatg aaccagattt tataatagca
    12181 gttggagcca gatttgcaga gccaattaaa gaagctgcta ctaaatatcc caaacagcaa
    12241 tttgcaatag ttgactatac ttataaagtt cagccagcta atgtaatttc tgtatcattt
    12301 caagataatg ttactggata tttagcagga cttattgcag gtaaaatgac tgatactggg
    12361 aaagtcggtt ttataggagg agttgagggt tctagtagag ataagtatga atctggattt
    12421 agaaaggggc ttaaaacttc aaataaagat gctgagttac tagttaagta ttcaaatata
    12481 tttgaaaacc ctgaatcagc tagaactatt gcaaaggaaa tgagagattc tgatagagat
    12541 gttgtatttt cagctacaga agatgatagt aaaagagcta ttcaggtagc aagagaaaat
    12601 ggtggtaaag ttatagctat taataaagac caatacgata tggctccaga taatgtaata
    12661 agttcaatta taaaagatgt agaacaacct gtatatgaac tgataaagaa cgttgcaaaa
    12721 gatggtttta agggaagtaa agtaatggaa tttaaaataa aagatgggga acttggcttg
    12781 acttcaaaga gcagtagaaa tataccacca gatgttttgg aatacataaa aaaagagtat
    12841 aacaaagtga aagatacata ttaattattg atgtagaaga ttataaaaat atattgctta
    12901 agtttagatt agcaataaaa agatatattt attaaatttg tgctaactgt acaaaatata
    12961 ttgattaagt ttagattagt gataaaaaga tatatttatt aaatttgtgt taacagtatg
    13021 gaatatactg cttaagttta gattggtgat aaaaggatat atttattaaa tttagtctaa
    13081 ctgtacaaaa tatattgatt gagtttagat tagcaataaa aagatatatt tattaaattt
    13141 gtgctaactg tacggaatat actgcttaag tttagattag tgataaaaag atatatttat
    13201 taaatttgaa ccaactgtac aaagctatac taattaagct tagaataact atataaaatt
    13261 ataacaataa gtgtgtgggc agaaaaattc tgctacacac tttatttata ttcacataaa
    13321 aaatttatca aaaaaaagaa aaaggagtaa aaaatggaat ttacaagaga accatttata
    13381 ctagatgacg atttgtgtct agctttggtg gacaaaagaa ttagttatct aatggaaaat
    13441 gaattaaaat taagaaatat agagataata aaaacaatag aatgtaaaga attatatgaa
    13501 agcataaaat atcacccgga tatatgtatt tgtaatttag gaaaaggaga tataattgtt
    13561 gcgccgaatg tatataatca atacaaagag ttattaagta gatataaatt taatataatt
    13621 aagggagaag ctaatttatt aaatagatac ccttatgata taccttacaa tattgcgata
    13681 gttggtgact atgctataca caattttaag tatactgaca aagcaatatt agattatatt
    13741 gaaaataata aacttaaaaa gataaatata gagcagggct attctaaatg ctcaatctgt
    13801 atagtagata gaacgtctat aataacatca gataaaggta tttggaaaag tatgaagaat
    13861 acagaaatag agtgtttatt gatagaaaaa ggtcacataa atttatttga gatgaattat
    13921 ggatttatag gtggatgtac agggttgatt tctaaggata aactagcttt ttgtggagat
    13981 gttaaaaaac atcctgacta tgaacgtata aaaagttttg tagaaagtaa aaacaaggag
    14041 atagttacac ttagctgtga aaatttacta gatataggtt ctatagttcc tctcatgaca
    14101 agaaaggagc gataactttg gttgagaagg ataatatttc ttccatgaaa tttttgagga
    14161 ataataatgt aaacgataga ttaatatata cgaatgacat tgtagaagta gtgatagatt
    14221 ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg tactaaagct gaacaaagag
    14281 ctttaaatat tgatgagata tcaacggaaa taactagtat gataataagt ataatgaaag
    14341 agaaactttt gaaagaatac attctaaaat gctatgggcg tacatatcct gaagataaaa
    14401 ataatatata catatattca ctgaacatat ttgctaaaaa agagattttt atgagagaaa
    14461 cagtatttac tagggtgaga aattatatag aagaaaatga ttttataaat gtagaaggtt
    14521 ttattagatt tagaatgaga gaatttatga aatatatttc tgctataggt gatattgcag
    14581 ttgaggagta tttaataaag aaagaccaag atgaatttat aagagtttta aaatacttta
    14641 tagatactca agaagaaaag attgatttgc ttaaagttca tataatggaa gataatacat
    14701 ttgttttata cgataaaaat ggaaataaga tagacagtat agatgatgaa gaaattataa
    14761 atatggtaat aagagaaaat ttaaattatg aggacttttt aataagtacc ttattaactc
    14821 tatgtcccaa aaaaatagaa atattggatt tgttaaataa taattgctca aaggaaatta
    14881 tagatactgt agaagcaatt tttgaaaata aagttagtat aattatggaa aactagaatc
    14941 taagcatata aaagctatcc atataaaatt aaaaaaattc tttttaaatc gacacaaaag
    15001 acttataatt gtatataaag ctatagtata actagagtta ttaagtataa agaatatcta
    15061 cttgattaat gcaatatagc tggcaaatat acaattgata aggagtaatt ttataatgga
    15121 taatttaatt aggatactga tattagctgt tattggtgga tttataggtt atgttacgaa
    15181 tgtagttgct ataagactga tatttagacc aatagagcct attaaaatac ctattttaaa
    15241 tatagaaata gtaggtctta taccaaagag aagagcagaa atagcagcaa atgtaggaga
    15301 aataattcaa gaagaatttc tttctatgga cgaaatactt gcaaatatca ttactgacga
    15361 agataaggaa gaagttgtaa gatacataaa agcaagggta aaaattataa tacatgagaa
    15421 agtttcattt atcccgagtg gtataaaaaa catgatacaa gattatctag gagagataat
    15481 tgagtctgaa gttaagcaaa gtatagatga attgagtaaa aatataataa ataaagcaaa
    15541 tgaacgtata gatatacaaa aaatggtcga agataagatt aatgaactag atttatatga
    15601 attggaagag ataataataa gaatagctaa gaaagaatta aaacatatag agtttttggg
    15661 gcttgtctta gggtttttaa taggtatagc tcaagggtta attactatgt ttatttaaat
    15721 atatgagaag tagcatttat ttaagtacta attatattta cctatttgag tgaattactt
    15781 attaataaca tttagatatt aattgtattt acctatttga gtaaattact tattaatagc
    15841 atttagatat taattgtatt tacctatttg agtgaattac ttattaatag tatttagata
    15901 ttaattgtat ttacctattt gagtgaatta cttattaata gcatttagat attaattgta
    15961 tttatttatt tgattgtgtt acttattaat agtatttaag tatttactgt actacttatt
    16021 aaccatatta agtattgatt gtatttaagt atacaaaacc taaaaagagt acaaaaatta
    16081 gaagttagtt ttaataaaaa ttagttttag tatttatcta gtcatatcta tcatgcatgt
    16141 ggatacgttt taaaaatttt aaatttatga aaatattata atataactat aaatcaagag
    16201 attaatttaa tataaaaata taagaatatt ggtttacagc tgattgagat gaaaaataat
    16261 gggtaattaa tatattacat taatgttgat tgatgtataa ctatctgtta taatgaaaat
    16321 atattaaaaa tcatagtgtt gaagaggaag agtagagtag aaaccattct cagagaattt
    16381 gggtctatgg ctgagagccc atgtaatagg tctatttgaa aactaccttg gagctgagct
    16441 tattagcagt atttgtattt atactatacg tgaaagtgct cgggtgacga ccttatagtc
    16501 atcaagaggg ttgtatatac ttgtatacgc caacttgggt ggaaccgcga attaatatcg
    16561 tcccaaacat atttggggcg attttttatt acaaaaaatc taaaaattat ttcaataagg
    16621 aggaaaaaac aatgattaaa gttgctttaa aagatggctc aataaaagaa tttgaaaatg
    16681 ctatttctgt tatggatgta gctaaatcca ttagtgaagg attagctaga aatgtggtag
    16741 cagcgtctgt gaacggagag gttgtaggtc tggaccacat tatagatact gattgtgact
    16801 tgaatttatt taagtttgaa gataaagaag gtaaggaagt ttttagacat acatcagcgc
    16861 atatattagc tcaagctata aaaagacttt acccagaagc aaagcttgct ataggaccaa
    16921 gtatagaaaa tggattctac tatgatatag atttagacca tagattagtt ccagaggacc
    16981 tagagaaaat agaagctgaa atgaaaaaaa tagctaaaga agatttaaaa atagaaagat
    17041 ttgaacttcc tagaaatgaa gctttagagc ttatgaaaga acaaggagaa gactataagg
    17101 tagaacttat ttctgattta cctgaaagtg aaataatatc tttctacaag caaggtgatt
    17161 ttactgattt atgtagagga ccacatttac catctactaa aaaggtaaaa gctgttaaat
    17221 tacaaagtgt agcaggtgca tattggcgtg gtgacgaaaa taataagatg cttcaaagaa
    17281 tatatggaac ttcttttgag aaaaacaaag acttagaaga gtacttacat ttactagaag
    17341 aagctaaaaa gagagaccac agaaaattag gtaaagaatt aggattattt atgatacctg
    17401 aagaaggtcc aggattccct atgtttttac caaaaggtat ggaacttaaa aatgaattat
    17461 taaaattctg gagagaaata cacagaaaag ctggatatat tgagatagaa tctccaatca
    17521 tattaaatag aaaattatgg gagacttcag gacactggta tcattacaaa gaaaatatgt
    17581 atacagttaa aatagatgat gaggattatg ctataaaacc tatgaactgt cctggtggat
    17641 taatttacta taactctcaa ctacattcat atagagattt cccaatgaga gttgcagagc
    17701 ttggtagagt tcatagacat gagttatctg gtgcattaca aggattaatg agagttagag
    17761 catttactca agacgattca catatattca tgttaccaga gcaaattaag gacgaaataa
    17821 aaggagtagc taacttaata gatggtatat acaaaacttt tggatttgaa tataatttag
    17881 aattatctac aagaccagag aactctatgg gaagcgacga agagtgggaa gcagcagaaa
    17941 atggattaag agaagcttta gaagagttag gtctaccata tactattaat gagggtgatg
    18001 gagcattcta tggtcctaag atagacttcc atctaaaaga ttgtttagga agaacttggc
    18061 aatgtggtac tatccaatta gatatgcagc ttccaagaca atttgataat acttatattg
    18121 gtcaagatgg tgaaaagcat agaccagtta tgattcatag ggttgctttt ggtagtatag
    18181 aaagatttat aggtatatta atagagcatt atgctggtaa attcccagtt tggttatctc
    18241 caactcaagt taagatactt cctatatctg ataaatttat ggattatgca aatgaagtta
    18301 agaaagagtt atttgataag ggtataagag ttgaattaga tgatagagct gaaaaaattg
    18361 gatttaagat aagagaagct cagcttgaaa aagtgccata catgttaata gtaggtgaaa
    18421 aagaagtagc tgataataat gtttctgtta gatcaagaga taaaggtgaa ataggtagta
    18481 ttaaattaga tgaatttata gctagtattt caaaagaaat tgaatcaaga gaaagtatta
    18541 ttcaagacta atatatatta tattagtagc taagatattg ttatataaga taagtttaat
    18601 caatatgttg atatgttgat gcatagtgat taaatttatg aaaagatgag tataattaga
    18661 ggtacagtta atcatatttt tatgattaat gtacctctag ttttttgtat ggtagattta
    18721 ttaataaata tatcatagaa gtgttttgaa catggaaata tttatgtgca ttctttaaat
    18781 aaaagtttat tttttgagtg ataattaagt gcttgttggt aaggttatgg ctgtaaaaat
    18841 cataacttta ttttcatatt tgttccattt tcataaaaat tattatccct ttaagaaaat
    18901 ttcttaatcc tcttgaaata tttccttttt agtctaaagt taaatttctt tcttcaaaat
    18961 gaatatttaa atgaactaaa atttaagtac attttctaat cttatgagtc tatttttcat
    19021 agataattgc cctataatag aagaatctat gttggtgcta tgtggtgaca ataacagcat
    19081 tgtcagtgat taattaatgc tttataaatg attaattagt gttttatgtt atttttggac
    19141 ttatcctcta tacatagatt aatttattta actttagata gagagagaat gtcaagtaca
    19201 tacacagaca ttagagttta agaaagtgtt tatggagcaa gaacttttaa aagaggtagt
    19261 gacttagttt aatttcaaga aatgataaat acaaaagagg aaaaagagag gtgttgaaat
    19321 gatagaaaaa gtagaagaaa aatctaagat tattaaaaca tcaaaagaat ataagcgaac
    19381 tataattgaa gaaaaagata aagaatggac caaaaaatta aatgatatac ttagtagaag
    19441 tagtttttct aatgatgaat tagataaaat caaggcatta attccaaaag agattttgac
    19501 taatgaaaat gttggagaag ttgtgactga agatggatat gctaagcctg agtatgatga
    19561 ggtatttaaa tcattgttca ctttaaataa tgaatatgat ttacttgtaa attttataaa
    19621 tgatattcta aaagatgctc catatgctaa caggaatatc aaaccgttca ctcaaataaa
    19681 gagaataatt agagttgaaa ctgatccaac aattaattac attggagaga aaagacctaa
    19741 acttgatatt ttggctgaag atgaagaaaa taatcatata aatattgaga tgcaaagagc
    19801 ttttgagaac gattatttgg aaagagctga atattatctt agtcgtgtac atggtagaaa
    19861 gttagaagaa ggtaaagagt ataaagaaat tggaaaaact attggaatac atatactaaa
    19921 tcatgtaaaa tataatcaca tagaagatta tgtaaattgc ctgagattaa caatggacgg
    19981 gcatccagat atttattcta gtaaaactgc attatatttt atagagcttc caaaaattca
    20041 taaatctgac tatatagtaa atagaattat gctatgggga aaacttatta gtaatccttc
    20101 taacttagat gtaagagtta tagctaagaa tgattctatt attaaaaaag cacttgatag
    20161 attaaaagaa ttaggtagca atgaagaata tttattaaat ctgaaaagag gtgcttatat
    20221 catgaataaa agtagaaatt ttaaagaaga gattgaaaga gagacagcaa ttagagttgc
    20281 aaaagaaaaa gattataaaa taattataat gttgaaaaaa aatggtttta aattagatga
    20341 catattaaat aaatttaatg attttgactt aagtgaagat gagataaaag aagtatatga
    20401 aaataattga tgataaataa aaagtgaact tatataagtt tgctgaatcg gagtctggaa
    20461 atatttatat gtatttttta atgaatgaaa atttatttta aaaacaataa tttagaagta
    20521 cagttaatta tatttttatg atactgtact tctagttttt tctattgtag atttattatt
    20581 tactaataaa tctacaatag aaatgctttt gttgtaagaa tcattttatc taatgattgt
    20641 tttttataat agttaaattt ccatttgtag tgtttaaata taaatctata acagcatttc
    20701 tataaatgtt ataaatcact ataatgattc aactcaaagt tactgcttaa agaagcagag
    20761 attttatcaa ggtatatcat ggaaa
//
LOCUS       DAYAKB010000063        20311 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.063, whole genome shotgun sequence.
ACCESSION   DAYAKB010000063 DAYAKB010000000
VERSION     DAYAKB010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.063"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            664..1992
                     /locus_tag="ACGI3L_002755"
     CDS             664..1992
                     /locus_tag="ACGI3L_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9198453.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2745..3578
                     /locus_tag="ACGI3L_002756"
     CDS             2745..3578
                     /locus_tag="ACGI3L_002756"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9198454.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3647..4603
                     /locus_tag="ACGI3L_002757"
     CDS             3647..4603
                     /locus_tag="ACGI3L_002757"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9198455.1"
                     /translation="MNKKLYIGMVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVL
                     SATNNYINGQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVD
                     SKYQELEDKMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDM
                     EAYYTSHKKDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESF
                     ESLAKKYSDDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVK
                     VTDKRERQKSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4655..5137
                     /locus_tag="ACGI3L_002758"
     CDS             4655..5137
                     /locus_tag="ACGI3L_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9198456.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            5149..6018
                     /locus_tag="ACGI3L_002759"
     CDS             5149..6018
                     /locus_tag="ACGI3L_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HFG9198457.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            6061..6816
                     /locus_tag="ACGI3L_002760"
     CDS             6061..6816
                     /locus_tag="ACGI3L_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HFG9198458.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLASLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6858..7679
                     /locus_tag="ACGI3L_002761"
     CDS             6858..7679
                     /locus_tag="ACGI3L_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HFG9198459.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7684..8445
                     /locus_tag="ACGI3L_002762"
     CDS             7684..8445
                     /locus_tag="ACGI3L_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HFG9198460.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8606..8863
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8976..9215
                     /locus_tag="ACGI3L_002763"
     CDS             8976..9215
                     /locus_tag="ACGI3L_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFG9198461.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9468..10514
                     /gene="ilvC"
                     /locus_tag="ACGI3L_002764"
     CDS             9468..10514
                     /gene="ilvC"
                     /locus_tag="ACGI3L_002764"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFG9198462.1"
                     /translation="MSNKNKYHKNKKKYWEEMKMARMYYEKDVDLEVLKNKKVAVLGY
                     GSQGHAHAQNLRDNGVHVVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPD
                     EKQKKVYEESVKDNLKEGQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVF
                     TKGSGVPALFAVYQDYTKKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVL
                     CGGISELIKLGYKTLVDAGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEY
                     GDYVSGKRVITDVAKQGMQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIA
                     EVGRNLRSMMSFLK"
     gene            10567..12255
                     /gene="ilvB"
                     /locus_tag="ACGI3L_002765"
     CDS             10567..12255
                     /gene="ilvB"
                     /locus_tag="ACGI3L_002765"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HFG9198463.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            12466..13143
                     /locus_tag="ACGI3L_002766"
     CDS             12466..13143
                     /locus_tag="ACGI3L_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9198464.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            13312..15348
                     /locus_tag="ACGI3L_002767"
     CDS             13312..15348
                     /locus_tag="ACGI3L_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HFG9198465.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPAGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(15539..16105)
                     /locus_tag="ACGI3L_002768"
     CDS             complement(15539..16105)
                     /locus_tag="ACGI3L_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9198466.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            16393..17328
                     /locus_tag="ACGI3L_002769"
     CDS             16393..17328
                     /locus_tag="ACGI3L_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="HFG9198467.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            17793..19007
                     /locus_tag="ACGI3L_002770"
     CDS             17793..19007
                     /locus_tag="ACGI3L_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9198468.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(19427..19948)
                     /locus_tag="ACGI3L_002771"
     CDS             complement(19427..19948)
                     /locus_tag="ACGI3L_002771"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9198469.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHKQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEIRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHKKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
BASE COUNT         8235 a         2007 c         3439 g         6630 t
ORIGIN      
        1 aataattcta gtacattatt tattttagaa aaaagataat tatctaatta tatttaagga
       61 taataatatg aaaataattt ttatattaaa aaatatgaat gaaaatagta ggttttataa
      121 aaaaacatat ttagatttta acatctcaaa ggagttttca aagctaatat ttcattttta
      181 aataaaaaaa taaaatatta gttttgattt ctggtttaaa ttgggttata ataaattgtc
      241 aaattattta ttaatataaa atagactata aaacaagcaa aaatcatact attatataaa
      301 agaccttaaa gatagaaaac tacagaaaga agccaaaatg tttttgaaaa aaatgaaatt
      361 ttattgcaaa aaaatcaaaa tgaatttaac ttaatagtta taatctattt ttagtgttac
      421 aaatatacaa tgtatattat acaatataaa aaatacattt acttagaagt attattatat
      481 ttggattttt ggtttttata atttttttat atttaaacat aactaaaaat aaaagattac
      541 taaagctaag tagagtttat tttattttaa taaataataa agctattttt ctatatattg
      601 gcataatata tgcttattta actatgaaat taaaattaaa taggattaat gaggaggaaa
      661 aaaatgggaa gtaatgaact gaaaaagact cttggcgtat cagcagcatt atcaactgtt
      721 gttggttccg ttataggagc gggcgtattt tttaaaccac aagcagtcta tacattaact
      781 ggaggagctc caggtcttgg tatattggca tggttaatag ctggaatcat aactataaca
      841 gctggtctta cagctgcaga ggtatcagtt gcgataccaa aaactggtgg aatgatggta
      901 tatataaaag aaatttatgg agaaaaatta ggttttttaa ctggatggat gcaaattgta
      961 ttattttatc cagggatgat ggcagcatta ggtgttatat ttggagaaca agcatcggca
     1021 ctaattggta gtccatcact tttacttcca atagcaattg gaattataat aatagttgca
     1081 gggcttaata tgttaggttc aaaaactgga ggagtcatac aaactgtttc tacaatttgt
     1141 aagttaatac cacttatttt aataatggtt gttggattta ttaaaggtgg tggaaataat
     1201 ccaatactta cacctatggt tggtgaagga ttaagcctgg gtagtgtact aggtcaagtt
     1261 ttaattgcta tattatttgc ttttgatgga tggatgaatg ttggtacttt agctggagaa
     1321 atgaagaatc ctggaaaaga ccttccaaaa gctataatag gtggattgtc agttgttatg
     1381 gctgtttatt ttataataaa tttagcgtat ctttgggtat taccagctaa tgaattagca
     1441 aattatgctt ctcctgcatc agcagttgct gaagttatat ttggttcaat gggtggaaaa
     1501 ataatatctg taggtatatt aatttcagtg tttggagcat taaatggatt tttactaact
     1561 ggttcaaggg tggcatatac tttagctaca gataagactt taccaaagta tggtatattt
     1621 tctaaattaa attctgctca agttccagca aatgcaatag cattagtatc tgttattgca
     1681 tctatatatg ctttgtcagg tcaatttaat ttattaactg acttagctgt atttgctact
     1741 tggatattct atgtattaac ttttataggg gttatgaaac ttagaaagac tcatccaaat
     1801 ataccaagag agtataaagt tccattatat cctattgttc ctataatagc tatagcaagt
     1861 ggtatatttg ttgtagttaa tcaattgtgt tttgcaggta tgaaaactac tatgatatct
     1921 ataggaggtc ttgtaataac agctataggc ttaccagtgt atgcttatat gactagagga
     1981 gtaaaaagat aaaccaagta gtttacaaat gcttcataat taaaataaaa gagactgtct
     2041 caaatagaga taagtctctt ttttattgtt aaaatggtaa agatatgttt aattttacaa
     2101 aaaaagagcg ttccatgaac taaaaagttt attttaaggt attcatttta tttttagttt
     2161 tttgattata aaattaaaca tctaaaaaat tatttatttt aaaatacttt attttaaagt
     2221 gttttttatc aaactaagtg gtatctgtac aacaaatatt atacatagct tttatgaaaa
     2281 ttaaatcttt ctgttatata taatagaata ttgtattata tagaaaatat tacctgatta
     2341 atatagtgat ttataaatga gattagaaaa ttttatttga taacaaaaat tagataatat
     2401 gaatatataa tgtatgtatt aaaaatgtgg caaatagttg ttttgctatt tattatttgt
     2461 ttaatatttc taatttataa aaaaaaaatt ataaatttta aaaattataa atgacatttt
     2521 aactagaatt aattgtaaaa aacactatat aatactcaat tttcaacatt ctatacaatt
     2581 atacagaaat tatacagcat aataatcacc gaaataacaa attttaaaaa ttaagcaaaa
     2641 ctttttgtcg aagttcaacg tctatatata tgtagtgtaa atttttggga taaaatacta
     2701 caaaaatata aatgtaaaaa tatagtaata ttggaggtcg aacgatgaga aataaaaaga
     2761 aaaaaataaa tagaaagaag ttgtatttgc ttttaagtgc tattgtagtg tgtctggctt
     2821 ttatagtagt tggtgttcgc gtcagctctt taaatatgaa ggaaaatgaa attagtagaa
     2881 atgcaaaact gtcaagttct actattacag atatagtatc taatacatca atagaagtta
     2941 gtaaagggcc aagtaaaagt tctggaaaaa tagcatacat aactatagat gatggtccat
     3001 ctaaatttac tgaccagatg ataaaaactt taaataaata caatgttaaa gcaacttttt
     3061 ttatgataga tgggaatatg aaggaatatc cacagcaagt taaaaatata attaaaaatg
     3121 ggaacacagc aggttttcat agtgtatcac atgatattca caagctttat gttactagta
     3181 catcagcaaa agaggaattt gatacaaatg atcaaacttt ttataagata actggtaaac
     3241 attcaaaagt aataagaata ccttatggaa gcaaaccata tacaccacaa gcctcttatc
     3301 aggctttagt tgatgctgga tataaaattt gggactggga cttagataca gaagactgga
     3361 gatctaattc ttctcaaatt gtacaaaatg taaaaaatca tattaagaat agaaaaggtg
     3421 aagataaaga ccaacttgta gttttaatgc atgagaaaaa acagagtgca gaagctttag
     3481 attcagtttt aaaattctta tcagatgaag gttatgaatt tgcgccagta gatcaaaacc
     3541 aaataccaaa aaattattgg ttacgtaatt tagagtagtt aaaatataag aatattgatt
     3601 gatattttta gaaattgaga ataaaaatga gtgaggtgta ggtatattga ataaaaaact
     3661 ttatatagga atggtcggaa tattgtcttt gatgatggtt ggttgtaata aaagtttagc
     3721 aaaagtaaat gatgtggaaa tcacaaaaga acagtacaaa aaaacaaaag cagttttatc
     3781 tgctactaat aattatataa atgggcagtc tttagatgaa ttagaaaaaa ctttggataa
     3841 aaaaggtaga aataaattag aaaatgttat aatatcgttt atggtggata atgaactttt
     3901 atatcaagag gctaaggata aaggactaac tccaagtaaa agtgaagtag actcaaaata
     3961 tcaagaacta gaagataaga tgaatttgaa tacaagctat aaggaaaaaa tggacaaagc
     4021 aggtgttgat aaagattatt taaaacaaga aatatctaga gatttagcaa tagataaaaa
     4081 taaaaaggcc tttgaagata gaataaacat aagtgataat gatatggaag cctactatac
     4141 aagtcataaa aaagatttta atgtagaaga agtaagtgct tctcagatac ttatatcgac
     4201 tttagataaa aataaaaaag aagtaagcaa agataaaaaa gaagctttga agaagaaggc
     4261 agataatata ttgactaaaa tcaaaaatgg agaaagtttt gaaagtttgg ctaaaaaata
     4321 ttcggatgat aaagcaactg gaaaaaatgg aggacagcta ggatatttta caaaggatga
     4381 taaaaatgct gagtttacaa aggaagtgtt caaattaaag aaaaatgaag tttcaaatgt
     4441 gtttgaaact agttatggat atcatatagt caaagttact gataaaagag aaagacaaaa
     4501 aagttttaat gagtgtcaga gtttaataag agaatctatt ttaaatgaaa agtatattga
     4561 gcatataaaa aaactgaatg aagatgctaa aatagacaga tagaatttct aacagctcaa
     4621 tcctagcctg taatcggagg gagattttac aggaatgttt aagagtttaa agagaacgaa
     4681 agttgagaaa tacattatcg ataataaaga ctctttttat agaatagcat atagttatac
     4741 gaagaatgaa gaagatgcct tagatgtggt tcaagaagcc atgtataagg cactatactc
     4801 agtggaaaat attaaagaag taaattatat aaagacatgg ttttataaaa ttttagttag
     4861 aacgagtata gattttatta gaaaaaaccg taaatataat aatatgacag atattgacct
     4921 tatagatgag actggagagt atgataaata tactgatttg gatttaagaa gagctttgga
     4981 agaattacct attgaataca aatctattat aatattaaga ttttttgaag atttaaagat
     5041 tgaagaagta gcaataatat tggatgaaaa tgtgaatact gttaaaacta ggttatatac
     5101 tgctttaaaa aaactaaaat taaaaattga agagtaggga taaaaagaat gacaagcaaa
     5161 gaaaggttaa ataagttaaa agatgagtat cataaaattc caatacccaa gaaattagat
     5221 actataataa atcatgaaaa aatagaaaac atatatcgag agaaaaataa aaaagtaaat
     5281 agattaagat ttaaagttgc aatagccttt gcatgtatat ttacagtatt agtaaatata
     5341 agtcctgtat ttgcagacaa tttttctaag atacctgtaa ttggagcaat agtagaagta
     5401 ataactataa aaaattatag tttaaaaagt gaaaattatg aagctgagat tgatattcct
     5461 aaaatacgag gtttaaaaga taaaaactta gaacaaagat taaacagtag ttttatggaa
     5521 gatggaaaaa ggctttatca tcaattccaa gagagaatgg agaagataca atcatcaaag
     5581 aataaaggat ataaatcttt aagtttgagt tatagtgtaa aaaataattc taaaaaattt
     5641 ctatcaatag agatgacaaa aaatgagata gaggcttcat catatgtgag taaggtacat
     5701 tatactattg ataaaaaaag acaaatagtt ttgactttgc caatgctttt taaagatgat
     5761 aagtatataa aagttataag tgataatata aaagaacaaa tgagagaaca aatgaaaaag
     5821 gatagtacaa aatcctattt tatagatcaa aaaaaagact tgcctgttga agattttaaa
     5881 acaattaata agtatcagga tttttatttt aataaaaatg aagaccttgt aatttgtttt
     5941 gatgaatatg aagtagcacc tggttatatg ggcgcagttg agtttgtaat accatataaa
     6001 gtaataaaag atttgtaaat tgaatagtag tttatatata aatcttttaa ggaggacaat
     6061 atgactacat ataaaaaact taaaaaatct atatttaaaa ttgctatatt ttcaatatgc
     6121 ttattagctt cattagtaga tacaaaccct atatttgcag gtagttcctt taatgaaact
     6181 tcaaatagtg atacgataaa ggtgttaaat gctaagagta tcaactttaa acaagacaat
     6241 tatgaagtga atgtgagtat tcctaaaata aaaggtttaa aagataaaac tttagagaat
     6301 aaattaaaca atgagttttt gcaagatggg aaaaaaattt acagtgaatt tcaaaataaa
     6361 atgaaaaagg aagataataa gggtcataga tacctaaatg taatccataa tgtcaaaaat
     6421 aattctaagg actttttatc aatagaaatg acaaaagaag agatagaagc ttcctcatct
     6481 ataactaaga agcattacac tgttgataaa aatagaggaa tactattaaa tttaccaata
     6541 ttttttaaag atagtagata tattagagct ataagtgata atataaaaga gcagatgaga
     6601 aatcaaatta agaaagatga tacaaaatct tattttatag accaagataa agactcgcca
     6661 gtgaaagatt ttgaatctat aaataagtat caagattttt attttaataa aaatggaaat
     6721 cttgtgatta gttttgatga atatgaagta gctcctggtt atatgggagc agtagaattt
     6781 gtgataccaa ataaagtaat aaaaagacta agatagatat atagaagatt tttagataga
     6841 ctggtaagga gaattatatg aatatatatg aacaagcaat aagattaata gaaaataatg
     6901 aggatttcgc atttgctaca ataacgtctc attcaggttc aacaccacgt gaaactggag
     6961 caatgatgat tgtgaaaaat gattctacta tatttggctc agtaggagga ggtagtgtag
     7021 aagcagaatg tataaaacat gcaattaatg ttataaaaaa cagagaatca atgttgtata
     7081 aatttactct aaacaaatct gatgttgcaa aactaggaat gatatgtgga ggtactggag
     7141 aaatacaaat agattttata gatagtaaat taaaaagtaa tatagaaaaa tttaataaga
     7201 gactaaagga aaatacaagt aaagcatata tatttggtgc aggtcatatt tcaagagatg
     7261 ttgctgtgat actatctctt ttagaattta gaacagtagt aatagatgat agagaagaat
     7321 ttgctaatca tgaaaggttt ccagaatcag aagtagtagt tttagattct tttgaaaaca
     7381 taccagattt tccaactgac gaaaatagtt atataattat tttaacaaga ggtcatctat
     7441 atgattcaag tgctttagaa tgggctctta aaagagaggc tggttatata ggtatgattg
     7501 gaagtagaac aaaaattgga ttgacttacg aaaaactcat gaaaaaaggt tttaagaagg
     7561 aagaattatc aaaagtacat gcaccaatag gcataaaatt gaatgctcaa acaccagctg
     7621 aaatagctgt atgtatagct gctgaactta taaattgtag agctaataag gaaaaataaa
     7681 ctaatgaaca cagggagtaa agatattgat actttaaagg ttaattttag agggattgaa
     7741 ataaaagcag ttttagtata taaaaataga aaaaatattt ctataaaaat agatccattt
     7801 ggcaaaataa ctgtaatgag tcctcctaaa atatccaaaa aaataataaa agatataatt
     7861 attgaaaaag gagactggat acttaaaaag tcagaaaaat gtaaaggaag agaggaagta
     7921 tataaacaaa gaatgtttat aactggcgaa aaatttcttt atttaggtga agagtaccat
     7981 ttagttataa aagaactgtt gagagattct gtcaaaaaaa gtaactgtag aataactatt
     8041 aacgaatatc aaatagttgt tcagacaaat gatacaagta cagattttat taaaaaatct
     8101 ttaaaatctt ggtataagat ggaaagtgaa agaatagtat tagagagaat agattttctt
     8161 aaattaaatt gtgaaataat gaagcaatta gttccagcga gtgttaaggt aaaagaacaa
     8221 aataagagat ggggaagttg tacagctcaa aaaaatattt atataaactc aaaaatatct
     8281 atggcaagat tagatgtaat tgattatgta ataatacatg agtttagcca tttagtacat
     8341 atgaatcact ctaaaaaatt ctatgattta gtaaaatcca ttatgcccga ttataaagat
     8401 aaagaaaatt ggctaaaaat aaatggatat aaaataataa tctgaaaacg attattccaa
     8461 aatataggcg taaagtataa aagaagtatt attgtgaaaa aaataaataa tctgaaaatt
     8521 ttaaaaaaag tcattgacat tgtaaatgat agggaatata atctatatta acaacaaaac
     8581 agaattaaaa tataaaatta aaaaattaaa agcaatgaca gagacaacaa tactaatagt
     8641 gttatccaca gagaaccaat gttgctgaga attggtgtta acagtagtat aatgatcact
     8701 ctggagcttt tgtactgaat atttttagta agtacaaacg tatgtcagcg ttacatgact
     8761 aaggttaagg taattaatta cccgacctga aaaaagaggg gtagatgtat tttttatatc
     8821 tacaaataag gtggtaccgc ggaatataac tttcgtcctt ataagtaata tttatattgc
     8881 ttataaagat gaaagttttt ttattttaag cgatataaat aaatttaatc catataaaat
     8941 taataaaaaa ataataaaaa taaggaggga tttttatgga aaatactgta tatgctaaat
     9001 taaaccaagg aatagattct tttttaagag tggctatgac tctaagaaga agagaggttg
     9061 atatacaatc aataagtatg actgtagata atatgaataa ttcaggtata aaattaatag
     9121 taaatgaaga aaagacatcc ttagattctg tcttaaacca tatgaaaaaa ctacatgata
     9181 taagagagat aactgttgaa agaatgagac attaattaaa tatattttat aaagctaaag
     9241 ataaatatgc ttattttaaa ataaaaaact aaagataaat attaaataag aaaaatctta
     9301 gattaaaata taagtgtcat tgaatttatt agtttatcac agttaataaa tttattagtt
     9361 tgttgtagct aataaaaact gaaaattcta aaattataat tgtaagatta tataaattta
     9421 gaatttaaat ctgttgaata atattaaaac aatgataatg agtatgaatt tctaataaaa
     9481 ataaatatca taaaaataag aaaaagtatt gggaggaaat gaaaatggca agaatgtatt
     9541 atgaaaaaga tgtggattta gaagttttaa aaaataaaaa ggttgcagtt ttaggttatg
     9601 gaagtcaagg acatgcacat gcacaaaatc ttagagataa cggtgtacat gtagtgatag
     9661 gtctttatga cggaagtaaa tcagcacaaa aagcaaaaga agatggattt gaagttaaga
     9721 gtgtagcaga agctacaaaa gaaagtgatt tgacaatgat gttaatgcct gatgaaaaac
     9781 aaaagaaagt ttatgaagag agtgtaaagg ataacttaaa agaaggccag acattagctt
     9841 ttgctcatgg attcaatata cattataatc aagtacaacc accagaattt gttgatgttg
     9901 taatggtagc tcctaaagga cctggtcact tagttagaaa tgtatttaca aagggaagtg
     9961 gagttcctgc actatttgca gtatatcaag actacactaa aaaagctaca gagacagttt
    10021 tagcatatgc aaaagggata ggagcaacaa gagcaggtgt tttagaaact acttttaaag
    10081 aagaaacaga aacagattta tttggagaac aatcagtact ttgtggtgga ataagtgaac
    10141 ttataaaatt gggatataaa acgcttgtag atgcaggtta tcaaaaagaa gtagcatatt
    10201 ttgaatgttt acatgaaatg aaactaatag tcgaccttat atatgaaggt ggatttgaaa
    10261 gaatgagata tagtataagt gacacagcag aatatggaga ttatgtatct ggtaaaaggg
    10321 taataactga tgttgcaaaa caaggtatgc aaaatgtttt agaggatata caaaatggaa
    10381 aatttgcaaa agcgtggatt aaagaaaatg aagaaggacg tgaaaacttc ctaaaaacta
    10441 gagaagaaga atataataca gaaattgccg aagttggtag aaatctaaga agtatgatgt
    10501 cattcttaaa ataaatatat attaaatgga ttagtttgag ggaaagagtg gtgtatagta
    10561 gtgcgtatga atggagcaaa ggtaatttta gaatgtttaa agaaagaggg aattgacaca
    10621 atatttggat atcctggtgg agccgtgata cctctttatg atgctctata cgattattca
    10681 gatgatttta aacatataag gacatcccat gaacaaggtt tagttcatgc tgcagatggg
    10741 tacgcaagaa gtactaatac agtaggagtt tgttttacaa catctggtcc aggagcaaca
    10801 aatgccataa ctggaatagc aacagctttt atggattctt cacctatggt tgtaatttca
    10861 gggcaggtgc caactagttt attaggaaaa gattcttttc aagaaattga cataactgga
    10921 gcaacattat ctatgacaaa acataattat ttagttagaa acactaaaga attagttcct
    10981 acaataaaag aagcttttag agttgcaaat tcaggtagaa aaggacctgt acttgtagat
    11041 gttccaaaag atttattttt agcagaaatg gattttagtg gtgaggacta tgatttatgt
    11101 caaatagatg attatatgga ttataagagt gattttgatc tagatgatga aactaatatt
    11161 aagcttttaa atgaagcaat agatatcata aaagaatcta aaaagcctat aatatatgca
    11221 ggtggaggtg ttaaatcttc agacagtgag gaaattcttg aaaaatttgc aactaagata
    11281 gatacacccg tactaaatac acttatgggg cttggaaata tagatagaaa gaatgaatta
    11341 tctcttggaa tggttggaat gcatggaagt agagaaagta atttagcact ttctaattca
    11401 gatttagtaa tagcgatagg tgcgagattt agtgatagag tgataagtaa aagttctgaa
    11461 tttgctaaaa atgcaaaaat aatacacata gacatagacc catctgaaat aagtaaaaat
    11521 atagaatcta atgtatcttt ggttggagat gtaaagctag tccttagttt attaattgaa
    11581 agggttgaaa gtaagaataa tagcaattgg aaagaagaga taaagagatt tagaaagagt
    11641 gagggtgtac aaacatatga atttcatcca caaaatatac ttaaaaaaat aaatgaaaaa
    11701 tatgaaacat taaagaaacc cactgtggta gtaactgatg tcggtcaaca tcaaatgtgg
    11761 gctgctaagt actggaattt taaaggtaat aaaagtttta taacatcagc agggttagga
    11821 actatgggat ttggtttagg tgcagctatt ggaactaaag ttggtaatgt agataaaaat
    11881 gtggttttag tcactggtga tggaagtttt agaatgaact gtaatgaact agctacagtt
    11941 gcaaattata atgtacctat gcttatttta ctactcaata atagaacatt aggaatggta
    12001 aggcaatggc aaaagttatt ttccaatcaa agatactctc aaactgacat taatgaaaat
    12061 gtggattatg ttaaactcgt aaatgcatat aacattgatg gatataaggt atccagtatg
    12121 gaagaattag gaaaggcgct agatatgata gattttaata aacctgtatt tttgcaatgt
    12181 gatatagata aggattatga tgtttatcct attgtagcac ctaatgatgc attggaaaat
    12241 ttgatatgta actaaaactt atactgaata ttgataaaat tttttattaa atttttatta
    12301 gtattcagtt tttgttgttt agagatagat tggcattttt tatttttgca aataaatcaa
    12361 tgactatata attaagaact tattaaattt taattataca atttagaata gtattacaac
    12421 ttaagtaaat aataattttg aataataatt tacggaggta ttcatatgtt taaacacgat
    12481 aaagcattat taaaagaagt aaaagtagaa agaccaaatc ctcaatatgc tgttttaatg
    12541 caagaacagt tgggtggtgc aaatggagag ttaaaagcag ctatgcaata cttgtcccaa
    12601 agttttagaa taaaagaccc tcaaataaaa gatttatttc ttgatatagc agcagaagag
    12661 cttagccata tggaaatggt agcacaaact ataaatttat taaatggaca tgatgttgat
    12721 tataatgcag ttaatacagg cgaaatagaa acacatgtat taactggtct atcaccagtc
    12781 ttaataaact catcaggagc tccttggact gctaattacg ttacagttac aggggattta
    12841 gtagctgact tactttcaaa tatagcttct gaacaaagag ctaaggtagt ttatgagtac
    12901 ttgtatagac aaatagatga taaatatgta aaagaaacaa tagatttctt acttaataga
    12961 gaagaagcac ataatgctct atttagagat gctttaaata aagttaaaga tacaggttca
    13021 aatagagatt ttggagttac agaagattct aaattatatt tcgatttgtc tactccaggg
    13081 ccaaatcacg atactaagat agatattaat cctccttctt ttgaaaaacc tttaaaaaaa
    13141 taatttgata ttttttattt tgttttagta gttataaaaa ttatttacta gaagaattaa
    13201 ttatatgaaa aattaaatat gtatagttaa aaatgggtat acacttatta taagtgtata
    13261 tctatttgtt tattgcaaaa catataataa aataacaaat gaggtggtat tttggacagt
    13321 aatagaaaac ctaataatct aataaatgaa aaatctccat atcttttaca gcatgcttat
    13381 aatcctataa actggtatag ttggaatgat gaggctttta aaaaagcaaa agaagaggat
    13441 aaaccaatat ttttaagtgt aggatattca acatgtcatt ggtgccatgt tatggaaaaa
    13501 gaatcttttg aagatgaaga agttgctgaa ataatgaata gaaactttgt ggcaataaaa
    13561 gtagataaag aggaaagacc tgatgtagat agtgtgtata tgacagtttg ccaagctatg
    13621 acaggtagtg gtggatggcc aatgaccata ataatgacac cagataaaaa accttttttt
    13681 gcgggaacat atttcccaaa atattcaagg tataatagac ctggagttat agatttatta
    13741 gagaatgtat ctgaaaagtg gaatacaagc agagatatat taataaaatc tggagatgaa
    13801 ataatagaag ctcttaagga tgattttggt gtaaaaaata ctgagggtga tttatcaaaa
    13861 gagatgttga gttcatcagt tagagtattt aaggctattt atgatgaaaa gtatggtggt
    13921 tttggtaatg ctcctaaatt tccaagtcct cagaatctta tgtttttaat gaaatattat
    13981 agtatagaaa aagacaaaga tgtgttaaaa atggtggaaa aaactttaga tggaatgtat
    14041 agaggaggct tgtttgatca tattggattt gggttttcaa gatactctac tgataaaaag
    14101 tggttggctc ctcattttga aaaaatgcta tatgataatg ctatgcttac tatagctttt
    14161 ttagatgcgt ataaaataac aaagaaagag ttgtataaag aaattgctat aaaaactata
    14221 gattatgtag ttagagagat gaaggataaa gaaggtgggt tttattcagc acaggatgct
    14281 gatagtgaag gtgaagaagg taaattttat acatttaatc ctcttgagat aattgaagtt
    14341 ttgggtgaag aagatggaat tttctttaat aattattttg atataactag tagtggaaat
    14401 tttgaaggca aaagtattcc taatcttata aaaaataaag aatatgagag acataatgaa
    14461 aagatagctg accttagtaa aaaggtattt gaatatagaa aagaaagaac atctttgcat
    14521 aaagatgaca agatacttac atcatggaat gcattgatga tagttgcttt aacaaaggca
    14581 tatagtactt taaaaaatga catatattta gagtattcaa ataagtgtct taactttata
    14641 aataataatc ttgtaaatga gtcaggtaga ttattagcta gatatagaga tggaagttcc
    14701 gactatttag catatttaga tgattatgct tttttaatct gggcgtatat agagctttat
    14761 gagtcaacat ttaatatgaa atatttagaa aaggctttaa atttgaatga aagctgtatc
    14821 aacctttttt gggattatga aaaaagtgga ttttatatat atggtaaaga tagtgaaaat
    14881 ttaatagcaa ggccaaaaga tttgtatgat ggagctattc catcaggaaa ttctgttcaa
    14941 ttatacaatc ttataagact tgcgaaaatt actggagata atagacttga agaaatgtca
    15001 tataaacaat taaaactgta tgtggataat gtaaagagtt ctccagctgg ctacagcttt
    15061 tatatgcttt cattgatgtt tgaactttat tctactaagg aaattatatg tatttttaag
    15121 gaagattctg atttaattgc ctttaaagaa ttgataagtg aaaattttat accaaatgca
    15181 acttttttag caaagaaata caatgaagaa aacactatta taggtttttt aaataactat
    15241 agattgaagg atgataagat tagttattac gtgtgtcaaa gtaatagttg tagtcaacca
    15301 attaatgatt tacaaaaatt aaaagatatg attttaggag tagaataatc ataatagtga
    15361 aaaaggagat gctttaaaat aaaagtctaa tcatctcctt tttttgtaca aaaaacagaa
    15421 aaagagttcc tgagaacacc taatctatgt aatgattgtt ttgttaaaaa ataaaaatga
    15481 cattatagtt atataaaata ttgtactata aaaaagtagt attatagatg cgatagtatt
    15541 aatcgttttt atttactctc tttcttcttt ttgcaaattc ttcaagtgct tcagatttaa
    15601 ttttatctat ttcttcatat tccataaaat tagcatcttc ttcaaagcca tcttgttctt
    15661 caccattaaa acgatacatt ttttttagta aactccataa ggtctctaat tcatctttgg
    15721 taaattcgtg aaatacatct gccataaagt ttattccagt cctactacat gttaccataa
    15781 ccttttttcc taagtctgta actttaacat taattgctct cttatcatga ggacttggaa
    15841 ttacatcaac atatccattt ttttcaagat tagcaactag tctatttata ttttgtttac
    15901 ttgtacccat ttttcttgca atattattta atgttgtttc ttcctctggt aaatgaagaa
    15961 ttgataaaat agtcatatac tgtcttgaag taagtatacc aaaatattta tctccttcta
    16021 tttgtatttt gtttgtaagg gtaaaaagag ttgcatatgt ttgattcatt aaaaagagtt
    16081 cttttagttc atttgaataa tccatgaaat atatctcctt tatttttaga tgttgttttg
    16141 tcgaaaacag aatatcatga attaattcta atgtcaatat ggtgtcaaaa tatattaaag
    16201 tattactttt ttatgtaact attaattaat taaattattg tataatttta tgtaaaaact
    16261 tctatgtacc aatgataact tctatgagga attaataatt cttaaatttt ttagaaagat
    16321 tttgacttga aaatacttgt aatataatat ataaattaat atactgaata aaatcaatct
    16381 ggagggataa ttatgaagtg tacaaacttt actttcaaag gagaggaagg tttagatata
    16441 tatacatata aatgggaaga tgaaaatata aaaaaaccaa aggcagttat ccaaattgca
    16501 catggaatgg ctgaaactgc acaaaggtat gagacttttg ccaaggtact tactaaaaat
    16561 ggttatatag tatatatcaa tgaccataga ggtcatggga aaactgcaaa gataatagaa
    16621 aatgttggac atttagctga aaaagaagga tttagatgtc ttgtagagga catgtatact
    16681 ttaacaaata ttataaagaa agaaaatgaa gatctgccaa tttatctatt tggacacagc
    16741 atgggttcat ttgcaagtca aagatatata atggattaca gtaataattt atctggtctt
    16801 atactatgtg gttcaaatgg aaagcaagga atcattctaa atcttgctca tctgataatc
    16861 aatcgtgaga ttaaaaagta tggaagacgt tctaaaagta ataaaataaa taatttgata
    16921 tttggcggcg aaataataag aagaaatgaa aagactaagt ttgactggtt aagtagagat
    16981 aaagaacaag ttgaaaaata tataaatgac ccattttgtg gagtagtgtg tagttgtggc
    17041 tttttttatg atttagttca agggttaaaa gaaattgagg ataaagaaaa cttaaaaaaa
    17101 gtgccacttg atatacctat ttacataata tctggagata aagaccccat aggaaaaaat
    17161 ggtaaaggag tcttaagact aagggataga tatataaaat taggagtaaa agatgtaact
    17221 tgcaaacttt acaaagatgg aaggcatgaa ttgttgaatg aaataaatag agaagaagtt
    17281 tttgaggata taatttgttg gttaaataat aaaatagaaa tattgtaata aaaaaatata
    17341 atgatatatt tactttaaat ttatttatat ataatatttg aaaagtggat tatgtatatg
    17401 caaagtagaa aagagagagc ccagaagtga ttttttgcta taatgccatt tattgaatag
    17461 gtgggtgtta ttataaataa attattaaca ctcagtatta ttatcattgt atatggaatt
    17521 tattttattt aaaattcctt gaaagtttaa atatagtaag ttgtagtaaa gagaaaatat
    17581 aaatatttaa atgctattta atgtgaatct attaattagg ttatacttaa acttaattaa
    17641 tagattttat atttcaagac aatgagatag ggttttagat taaaatataa ccaatggtta
    17701 aattacagac attttgttaa ctttccctcg atttactagt aaatattttt tttatatact
    17761 taaattacaa cagatgtact agggaggtat atatgcaaat taaaataggt aaagtcatac
    17821 agtgtcttag aaaagaacga aatttaactc aagaacaatt agcaaagttt ataggtgtgt
    17881 caacaccagc agtatctaag tgggagagtg gaaattctta cccagatata gaattattgc
    17941 ctttattagc agactttttt aatgtgtcta ttgataagct tttaaattac aagattgatt
    18001 taagtgaaga agaagtaatg aaaatttata aagaattaga atcaggcttt gctagaattg
    18061 aaattgattt atcaacagaa gaaccaaaag aagaatttag acaagattta gaatctgtaa
    18121 aaaagctttc caatatgtat atagagaagt atcctaaaag ctatttattg aagctaagga
    18181 tatgttcgct gtatcagatg tattcatata aatttggtaa gagtgaactt aatgacagag
    18241 taaaagaaac aacgaatatt cttgaagata tagtgagaaa tacagatgat atccaaataa
    18301 aagaaacagc tcttattata ttatcaaacg catattgtat gttggaggat tatgaaaagg
    18361 cagagttgta tttaaatatg atacataagt caatagggga tacaagtgtt aatttagcta
    18421 tgatatattt aaagcaaaat agacttgaag aagcagaaat attgcttcaa aataaattgt
    18481 ttagtaatgt atttaatata agcatggatt gtaagggaat aattaatgta tacaaaaatc
    18541 aatacaagga attaaagaaa aaattggaga atagaaattt taataaaaat gcaattgaga
    18601 gagaaatgga gtatataaaa aataagttgc tggggtatgc aaatctttct ttagaaataa
    18661 aaaaaatgct cagtgaagat aaaggtgcat tttttagtat gtatatggat tatatggaat
    18721 tatctctaat ttttttattt tttaacatga aagaagaagc aaaaaaagct ttatatagtc
    18781 taaaagaaat attagaaaaa tatcctatac atgaaagttt ggatgtaagt caaatgagat
    18841 tttttgataa ggtagagtct aaaaatttat atacttttaa tatatataca aacttgttaa
    18901 ttgtacttaa tgatgacagt tataatgagc ttagagaaga accaattttt aaggatgtaa
    18961 ttgaaaagat tttagatatg gaaaaaatgt tgaaaaataa agaataagta aaaatttaat
    19021 ataggactta aagattaatc aaattaaaag aaagtgtttc aaaataaaaa tttgaatcac
    19081 cttttttgtc ggtcttaaac agttatttag aaaaatagag gtttcaaaat agaaatctga
    19141 attatctgta ttattacaca aaaatagaaa cctaaattta taaaaataga ataaaatttg
    19201 ttatataaaa tgtaattttg tctataaaat ctcacctgtt ttcttaactt taagcgtgaa
    19261 aaagaggatg tatcatgaat tttttagttc atgatgcatc ctgctttgta tgaaatccaa
    19321 tatatcttta ttatttaaac aatggaaaag agtcttattt atattttgag acatctcttt
    19381 tatttaatta tgaagtttta tacagttcaa taaataggaa ttatatttag aaactcatga
    19441 cattatttct tagatagtga ttaaatttat catattccat tttagataac ttttctgggt
    19501 aagacattac aatcaggtta tgcccattaa attttttatg gtatggtgga tgaatgtgtt
    19561 cataattatt tgtcttatat tttactcttt catagaacgc cttgcgataa attgaaatct
    19621 catcaattgg aaggtcaatt tctaaaataa tagtttttcc tttcttattt aaaagctcta
    19681 acgctctttg cccatatcta ttattgcgaa tttctggaaa aatgcagaaa tgttctacat
    19741 agataaagtt atctgtttcc caacataaaa ttatgccgac aaactggttt ttatcataaa
    19801 ttaaattgaa ttgatattct ttatttttca aaatttctgc ttgcaaagaa gattttcttt
    19861 gtttatgaaa tgggaaacta attttatata attccatagc cttgtaatat aatttatttt
    19921 cactggttct taaccgttca aatttcactt tactcctcct aatcacgaaa attccaattt
    19981 atttatgagt tcattttacc atagtcagta tttgcataca atgtgtttta agttgagtgt
    20041 catttctttc ttttatttat gcttatatct catagtctaa gagataattg cttaagacat
    20101 aactaaaaac tattatatta agctttgata atctaaaaac agtatattta tggacttttc
    20161 taggtctaaa agtaatctta ataattttag aagttacaaa aaagttacat aaatttggaa
    20221 agctataata tacatatata atataaggtt aaaactgtaa tgaataatat taatttaaaa
    20281 tttgaacatg gaaggagatt attatggaga a
//
LOCUS       DAYAKB010000064        20252 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.064, whole genome shotgun sequence.
ACCESSION   DAYAKB010000064 DAYAKB010000000
VERSION     DAYAKB010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20252
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.064"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(178..1707)
                     /locus_tag="ACGI3L_002772"
     CDS             complement(178..1707)
                     /locus_tag="ACGI3L_002772"
                     /inference="COORDINATES: protein motif:HMM:NF012862.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase domain-containing protein"
                     /protein_id="HFG9198470.1"
                     /translation="MKSLKALIVGVSKYSIVKNKDLLFCKNDIIEINNVLHKRLGITS
                     NNIRTLGMEYEVRKDLFFKTFQEISDSIGDDDTFIFYFSGHGCICNNGVHYLVLSDEL
                     VSIQFVIDFIEGLNCKNKIVFIDCCFAGKFNVSDKQKINIKDIFSLFDRKGCAVLVSS
                     SEYQESFSLPDSSISRFTSLLSEALRNEYIVRKGELSLRAISKYINLRMSILNKNYIN
                     CKQNPIFRSNILGDIYFNVKDYKSYIKKKVFQEHDDYIIYNVKSLHISIIKRYSVEVI
                     LKNKFSYCDISEISKEVFDIVKSVEVYNSEIGEDRLKGKDANIIWVYFGKDEIDMING
                     IYMCKTTWIDKYQEKDIWYSVNGKNKFFINGVHTETYDNYESLKSYISQNTITKEKAV
                     YEVKEILTNMINISEEIISFYNEYENKKICEDNIFQIIDSRKKKMDECYNKVINLDFP
                     PIEIKDWFDKCINLVSTIQNFGVYWDHSRTEENRKQCMEMNIEDYYKDLREVIRLSEE
                     I"
     gene            complement(2406..3836)
                     /gene="dcm"
                     /locus_tag="ACGI3L_002773"
     CDS             complement(2406..3836)
                     /gene="dcm"
                     /locus_tag="ACGI3L_002773"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFG9198471.1"
                     /translation="MKKITIDKNRVRKIMKEKNIRSQNQLALNMGITKNQLSAILSEK
                     FTPIKSNVEKLCEVLDIGFDEIMCLEDVNEKQLKFTNICSSNKDYIEHRDCTYKELSE
                     YELNPRERNKNNKHIDISNVLAKRAYTCVELFAGAGGLALGLEKAGFKEVGLVEWDKY
                     ACDTLKLNRPDWNVIQGDIVKIAENGIKNYIDNNIEIDLLSGGYPCQAFSYAGKKLGL
                     EDVRGTLFYSYAKILEELKPKVFLAENVRGLVSHDGGKTLKTMIDVFSEIGYNVKYEI
                     LKAVNYGVAQKRERVIIIGTRKDLSHVDFKFPKSFEYVATLRDALKNVPKSEGARYPE
                     RKKKVLDMVPPGGCWIDLPDEVARDYMGKSYYSGGGKRGMARRISWDEPCLTLTCSPA
                     QKQTERCHPDETRPFTTREYARIQSFPDEWEFTGSVSQVYKQIGNAVPVKLGKAIGLS
                     IVDYLNKIEKIYVTEEVAITEEEYVI"
     gene            4049..4765
                     /locus_tag="ACGI3L_002774"
     CDS             4049..4765
                     /locus_tag="ACGI3L_002774"
                     /inference="COORDINATES: protein motif:HMM:NF025864.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PmeII family type II restriction endonuclease"
                     /protein_id="HFG9198472.1"
                     /translation="MTELEKQEILDKAKDFFTNILVANHKKNTIKLNLKAFNINPFLV
                     KYLASFLTGSNKPEDIAKALIYPRVLGTSINTSFGTNLQKFCITTLDGFASTTSGIDI
                     EFIDCIDGRRKFCQIKAGPNTINKDDVKTIIDHFSSVKRLARTNGLSLSYNDLIVGVF
                     YGTENELNAHYKRINEEYPVVVGQDFWYRLTGDENFYFDLIDTIAQSALEEDCTVLLK
                     KTISNLADEISKDKSLFNQK"
     gene            complement(5010..5288)
                     /locus_tag="ACGI3L_002775"
     CDS             complement(5010..5288)
                     /locus_tag="ACGI3L_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6809 family protein"
                     /protein_id="HFG9198473.1"
                     /translation="MYDEIIEIYFDYWINEHMYRKVLEKDEYYNDRCKEIKKVNKLLE
                     KNLSEEKKMDVLIELNDLFNSVIEIERELGYKLGFKAGARFMIELLNS"
     gene            complement(5536..6870)
                     /locus_tag="ACGI3L_002776"
     CDS             complement(5536..6870)
                     /locus_tag="ACGI3L_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFG9198474.1"
                     /translation="MDNMSNLVKNTEAEQSILGSILLDSRKIEEIEILISEDMFYHQE
                     HKHIFNSVKDIHKRDEPIDIITLTEDLKKKGLIDYVGGISYLTKLSTIVPTIGNVSHY
                     IEIVIEKYKNRNIIDKFNKFKLGEIDDNTLIYQLEKYVNEVNQKLVKKDSSITAISER
                     AFEYINDEIEEGIDIGIKFLDETIGGLYSGELITIAAKSGRGKTALALQIMRNVVFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNEEEIIKYINALSTLNQENNLY
                     INDSVNTISGIKREIKSIKPDVVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPIIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALDYCKTMGIE
                     DIKELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGSLFSFKECKKVKEV"
     gene            complement(6883..7626)
                     /locus_tag="ACGI3L_002777"
     CDS             complement(6883..7626)
                     /locus_tag="ACGI3L_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198475.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNVNNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKANFDWIMSPNNFIK
                     ILEGNYQDKSINVKVDAEAYSPDDSQLKW"
     gene            complement(7647..7961)
                     /locus_tag="ACGI3L_002778"
     CDS             complement(7647..7961)
                     /locus_tag="ACGI3L_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198476.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEQEAQEKEKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDNWFIENANGI
                     KL"
     gene            complement(7965..8159)
                     /locus_tag="ACGI3L_002779"
     CDS             complement(7965..8159)
                     /locus_tag="ACGI3L_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9198477.1"
                     /translation="MKLKLKRIEKGIKQYELAEKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKEE"
     gene            8299..9159
                     /locus_tag="ACGI3L_002780"
     CDS             8299..9159
                     /locus_tag="ACGI3L_002780"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9198478.1"
                     /translation="MIDNTIGKKIKQYRKSINMSRDELANKIGCSVYAVAKYEQGQRK
                     PSLDMIKKISTALSIPINRLIIDESDLDTSTNNYTNLKELDLVVKTFDNYSAKLIGNN
                     ISKFRNINNISLKELSEKINCSENEIINYENGTKMPRIEILKKIALATYTKIEDLFGF
                     PLEEIKIDNQTILYRNPQTGYIIDNFLIDFINKDINIDNTPVSYYIDKSEFDLVIHIL
                     KNYGYDVKTDYKTKFEIADNADTIKPISLSFSDFKDFSKNLNWVINGLVENFIQENSN
                     GLIEDEDEEY"
     gene            9256..10008
                     /locus_tag="ACGI3L_002781"
     CDS             9256..10008
                     /locus_tag="ACGI3L_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9198479.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVSDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            9998..11164
                     /locus_tag="ACGI3L_002782"
     CDS             9998..11164
                     /locus_tag="ACGI3L_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9198480.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNSDILKAGELYRNDNYVFCNELGAPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKIEAVEKLDKIFSL"
     gene            complement(11281..11511)
                     /locus_tag="ACGI3L_002783"
     CDS             complement(11281..11511)
                     /locus_tag="ACGI3L_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198481.1"
                     /translation="MEANKTLLQSLYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGISDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(11760..16331)
                     /locus_tag="ACGI3L_002784"
     CDS             complement(11760..16331)
                     /locus_tag="ACGI3L_002784"
                     /inference="COORDINATES: protein motif:HMM:NF024685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFG9198482.1"
                     /translation="MTFEEIMEFNKPYNQKNFDELVNAIKDGYVVPYIGAGMSMLFKD
                     IYPSWSTFLNNTSEEYLEDEDKILFEKIEDYEKKAEFLYEELAKVRFSKHLKKVFGAG
                     YLDAKDKDDFIDKCVYLIPIIFGSGLIITTNYDKVLEKNYGLHNKTVLVSHPGHFEAL
                     NNALRNNELVLYKIHGDITEPTTSIVLTKEQYEKAYSNDELRKMLTQVYTSKELLFLG
                     CSLEKDRPLELLQQVSEAGTGHYAIIPVSSEKKKHRRIELENEYYIQTIMYPEGKHEC
                     VRIILERILEIVLPDEYRRLKDRSLKESRLTNLSCRLTEKWFQNQNNIQIKNLGDRYL
                     PELNVELSLENTFNALGKNEEFKQRFDEKTDKVLSSIKKQKINEVEVDVLVIEEIIQQ
                     FYDKANERLDIKLLKKHFEKISAALDDRINNFKNIIINEDCEKSKKREDEIYKLKQTQ
                     KDIYVYIKYLDSKEIKVVNSPYILLHSAGGMGKSHIIAHTIEKRNMDGHKSILFLGQH
                     FKLDKTPIKHMLEILEIECEFEELLEILNEIGEKEQQRVILFIDALNEGQGKELWKYY
                     LNGIVEQIKKYPWIGLILSIRSEYIPSLIDNNNKIKENLVFIEHQGFSSIEHKAMKKY
                     FDYYGIPYSNIPMPNQEFRNPLFLRIMCETFKGEEINLDTISFTDIYKNYLNILNLRI
                     SESCNYSRHANVVTEVLNEMIKYKYGDGLGNNLIPANKSVEIIINIASKYKINNVIID
                     ELIANGIVNKTVNLNDEEYMHVTYEKLEDYLYANLLVKELKEIGVVDFSHKYKYLVEY
                     EDILEVLAIVLSEETGSDIPNEIFEVFKNKETNYNVISAFINALKWRKKSTITEKTLD
                     YINKIVLGKSYYKIDFYNVLILISTKVNHTLNADYIVKYILQNTMADRDAIFIPIFNE
                     VYEEEESSIKRLLGWCFDFEGFDNTSNETIRLSAMMIATFLISSNRDLRDKSTKALVN
                     LLTGKMDIVIDLLKTFEDVDDPYIIERLYAVAFGCVVSEQSEEMIEALAVYVYNKIFD
                     VDYVYPNILLRDYAKNIVDYAKYKIDSSVLKDMNVEPPYKSIFPKVPTDEEIEGYKYD
                     YKASDFKDYYWSQNTILNSMEVEYTRDGQPGWYGDFGRYMFQHYFHKWKGLDYNDLKN
                     IAIKKVFDMGYDVNKHGKFDRTVQNGRLRDSKYERIGKKYQWIALYELAAQAADNYKI
                     EVYTDAYGTKKEIYCKGTFEPDIRNIDPTVMTVINNNNNKRVHNQLFQFSPIPNNEWL
                     GDFSDLPSINDMVNSVYKNQDFLLLNGWYTWKEENDFKNKNYKNPEKDMWVLINSYII
                     KNDQLEPIVNALKGKDFMGRWLTEPNSNYTLYNKEYYWADGYYFFQNSYYCGEEWVQI
                     DEHKNILEKDYKVLLPTYSYTTEREGDIFQEDFSGTWHKPCSTLFYGLKLRYGQGDSI
                     LYNDYGEVVCFESSELLNEEIGFFINKEIFLKYLNEQGYSVFWTMLAEKRVLEEPYMD
                     RKYIQPTISGVYTLNGENRLVGETIESEY"
     gene            complement(16736..18583)
                     /locus_tag="ACGI3L_002785"
     CDS             complement(16736..18583)
                     /locus_tag="ACGI3L_002785"
                     /EC_number="3.1.21.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DpnII family type II restriction endonuclease"
                     /protein_id="HFG9198483.1"
                     /translation="MKPILKWAGGKTQLLDILRKQMPTGCDFSSMTYIEPFVGAGALF
                     LYLLEEDIFNKYVINDINSKLINLYIKVRDDLEELITELTNLKEQYISYEEGSSDREK
                     MYYDIRDRFNILTNEKNIENEDCIKQASYFIFLNKTCFNGLYRENSRGEFNVPFGRYK
                     NPSFFDKNELEKLSMLLNKRDSRGELKVKILNKNYLNLENIIDKNCFVYLDPPYRPVT
                     IGGFNSYNKGNFNDDSQIELSKFYKVLDKIDTKLMLSNSDPKVLDEEDTFFDDLYSDF
                     NIKRVHAKRFINSKGNGRGFITELLITNYEEVGNQMELVKNIHKNKSKDEIFKELLEN
                     LKGTIASWDYYVNWNKALENTRKIEVQLNILNYLIGKEDIENETKNLLKEYPEVLSVI
                     PIVIASRDNEFKILDPSDEDMFKYKLFNFKKRKSISDEESELATEFLKKIKFLDLLKQ
                     KNIKNLVDYVFGVEVGLDTNARKNRTGSSMETLVERYVKNMCEKNNWSYLTQATVKKI
                     SEKWSIEVPTDKSKRKYDFAINNNGKIVLVEVNFYNGGGSKLKSVANEFTKLDKYIKD
                     GGFTFCWITDGLGWLESSIPLRDAFDKMDYIFNLDMVDKGSLEYIIKNL"
     gene            complement(19011..19360)
                     /gene="ssrA"
                     /locus_tag="ACGI3L_002786"
     tmRNA           complement(19011..19360)
                     /gene="ssrA"
                     /locus_tag="ACGI3L_002786"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(19518..19973)
                     /gene="smpB"
                     /locus_tag="ACGI3L_002787"
     CDS             complement(19518..19973)
                     /gene="smpB"
                     /locus_tag="ACGI3L_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFG9198484.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT         6842 a         3345 c         1996 g         8069 t
ORIGIN      
        1 tttcaaaata aatatctaat tatttaaatc aataccaata taatttataa atggatttat
       61 aattgtatct tctatcatgt ttagtgtaaa caacttattt taatttaaat tcgtaaccaa
      121 caaagtacca atctgactta taattctata ttagtacaac tatggaaaaa tttaattcta
      181 tatctcctca cttaatctta tgacttctct taaatctttg taataatcct ctatattcat
      241 ttccatacat tgctttctat tttcctcagt tctactatga tcccaataaa ctccaaaatt
      301 ttgtatagtt gacactaagt ttatacattt atcaaaccaa tctttaattt caattggtgg
      361 aaaatctaaa tttataactt tattgtaaca ctcatccatt tttttctttc tactatctat
      421 aatttgaaaa atattatctt cacatatttt cttattttca tattcattat agaaggatat
      481 aatttcttca gatatgttta tcatatttgt taaaatttct ttaacttcgt atactgcctt
      541 ttctttagtg attgtatttt gacttatata tgattttaag ctttcgtagt tatcatatgt
      601 ttcagtgtga acaccgttga taaaaaattt atttttccca tttacactat accatatatc
      661 tttctcttga tatttatcaa tccaagtagt tttacacata tatattccat ttatcatatc
      721 aatttcatct ttgccaaaat atacccatat tatattagca tcttttcctt ttaatctatc
      781 ttctcctatt tcactattat aaacttcaac agacttaact atgtcaaaaa cctccttaga
      841 tatttctgat atatcacaat aggagaattt attttttaat ataacttcta ctgaatatct
      901 ttttattata cttatatgta aagatttgac attgtatatt atgtaatcgt catgctcttg
      961 aaaaactttc ttttttatat aagatttata atcttttaca ttaaaatata tatctcccag
     1021 tatgttagac ctaaagatag gattttgttt acagtttata taatttttgt tcaatatact
     1081 catacgcaaa ttaatatact tgcttattgc tcttaaagat aactcccctt ttcttactat
     1141 gtattcattt cttaacgctt ctgataataa acttgtaaat ctactaattg aactatctgg
     1201 aagagaaaat gattcttgat attcgctact tgatactaac actgcacatc cttttctatc
     1261 aaacaaggaa aatatgtctt taatatttat tttttgtttg tcacttacat taaatttacc
     1321 tgcaaagcaa caatcaataa atacaatttt atttttacaa tttaatcctt ctataaaatc
     1381 aattacaaat tgaatagaaa ctaattcatc acttaatact aagtaatgca ctccgttatt
     1441 acatatgcat ccatgccctg aaaagtaaaa tataaatgta tcatcatctc ctatagaatc
     1501 gcttatttct tgaaaagttt taaaaaataa atcttttctg acttcatact ccatacctaa
     1561 agttcttata ttattcgaag taatccccag tcttttatgt aacacattat taatttcaat
     1621 tatatcattt ttacaaaata gtaaatcttt atttttaact atactatatt tacttactcc
     1681 tacaattaat gcttttaagc ttttcatatt ccattccccc tttataattt ttcaatttaa
     1741 tatacttaaa atgatgtttt aattgtttta ttgattttat aaaagctagt atcacactac
     1801 ttttttgact ttttcattat ttacttttgt agttggatta taatttttca aggtaagtat
     1861 atatatattt atttacatcg cacccatata atttatatct ctgatttatc tgacctgaac
     1921 ttagtgtaat ttaaaccaat gtaaaatcat ctatctcttc accatatatt ttttaaaatt
     1981 ccccaaaata ttgatgttaa tagaatttca tgtgtttttt gtattctact atccataaga
     2041 attttaaagt gagtaaatat ttccaatcat ttatatctta tttaatatca ttttattccc
     2101 tcaagtattt atttaaattg ttatgcttta tttataaaat tatacataca tttctaaagt
     2161 tagacataca tctttaaaaa cctttaattt gtgctacttt ttttctaaaa ataataaata
     2221 tataaaaatt atatatacaa aaaattaagt tatgactagt ttataaataa gtacataata
     2281 aaattaaaga gagcaatttt ttttgctctc tttcaaaatt tatattaaat tgtaataata
     2341 aaaataaaaa cgctagttat ctaaggctaa tattttcaac gattatataa atatctacat
     2401 aacagttaaa ttacatactc ttcttcagtt attgcaactt cctcagtgac atatattttt
     2461 tctattttat taagataatc tactatactt aatccaatag cctttcctag cttaacagga
     2521 actgcatttc ctatctgctt gtacacctga ctaactgacc ctgtaaactc ccactcatca
     2581 ggaaaacttt gaattctagc atactctcta gttgtgaatg gtctagtctc atctggatga
     2641 cacctttcag tttgcttttg tgcaggacta catgttaaag ttaggcatgg ttcatcccaa
     2701 cttattcgcc ttgccatacc tctttttccg ccaccgctat aataactttt tcccatataa
     2761 tctcttgcca cctcatctgg caaatctatc caacacccac ctggtggtac catatctaac
     2821 acttttttct tcctctcagg atatctagct ccttccgatt ttggaacatt tttaagtgca
     2881 tctcttaacg tagcaacata ttcaaacgac ttagggaact taaaatccac atgtgacaaa
     2941 tcttttcttg ttcctattat aataactctt tccctctttt gtgcaactcc atagttcaca
     3001 gcctttagta tctcatattt tacattgtat ccaatctcgc taaatacatc tatcatagtc
     3061 tttaatgttt ttccaccatc atgagataca agacctctaa cattctctgc taaaaacacc
     3121 ttaggcttta actcttctag aattttagca tatgaataaa acaatgtccc tcttacatcc
     3181 tctaacccta gcttcttacc cgcatagcta aatgcttggc atggataacc acctgatagc
     3241 aaatctatct ctatattatt atcaatataa ttctttattc cattttccgc tattttaaca
     3301 atgtcaccct gtataacatt ccagtctggt ctatttaatt ttaatgtatc acaagcatat
     3361 ttatcccatt ctactaatcc aacctcttta aaaccagctt tttcaaggcc taatgctaat
     3421 cctcctgctc ctgcaaataa ttcaacacat gtatatgctc ttttagctag tacattactt
     3481 atatctatat gtttattatt tttatttctc tctctaggat ttaattcata ttcactgagt
     3541 tctttatatg tacagtctct atgctctata taatctttat tactgctaca aatatttgta
     3601 aatttcagtt gcttttcatt tacatcttcc aaacacataa tttcatcgaa tccaatatct
     3661 aacacttcac ataatttttc tacattactt tttataggtg taaatttttc tgataatatt
     3721 gcagataact gattcttagt tatgcccata tttaatgcca gttgattctg acttcttata
     3781 tttttctctt tcataatttt tctcactcta tttttatcaa tagttatttt tttcatttag
     3841 ttcacctctt aataaataat atacccttaa atagttaata aaatacatta actatttaag
     3901 gatatattat cataattcta atttttatgt aagtagttat aaaaacttaa aataaaatat
     3961 ctgtaaacaa cctaatatta cctcataatt ttacacatta tggaatatat tgtataatta
     4021 cattaatact ttttaggggg attattttat gactgaatta gaaaaacaag aaatactaga
     4081 taaagccaaa gattttttta caaatatttt ggttgctaat cataaaaaga atactattaa
     4141 gttaaattta aaggcattta atataaatcc ttttttagtt aaatacttag ctagtttctt
     4201 aacaggatca aataaacctg aagatattgc taaagcattg atttatccaa gagttctagg
     4261 cacttcgatt aatacgtcct tcggaactaa tttacaaaaa ttctgtatta ccactttaga
     4321 tggttttgcc tctacaactt ctggcattga tatagagttt attgattgta ttgatggtag
     4381 aaggaaattc tgtcaaatta aagctggacc aaacactatt aataaagacg atgttaaaac
     4441 tataattgac cactttagct cagttaaaag acttgctaga acaaatggac tttcattatc
     4501 ttataatgac ttaattgttg gtgtttttta tggaacagaa aatgagctta atgctcacta
     4561 taaaagaatt aatgaagagt atccagtagt tgttggtcaa gatttttggt ataggcttac
     4621 tggtgatgaa aatttttatt ttgatttaat agatacaatt gctcaatctg ctttagaaga
     4681 ggactgtact gttttactta aaaaaacaat atccaatcta gctgatgaaa tttctaaaga
     4741 taaatcttta ttcaatcaaa agtaatataa aaatgattaa atagcataat ttacattttt
     4801 agatatttaa aaataatatt caccaaacaa aattattaag taaaatgaaa tgtatcttat
     4861 aaaagctgag ctataagtaa atctttgtaa aaacaaattt acttatagct tttttatgtt
     4921 caaaaaacac aaattatata ctatttaata tattataaac ttttatttgt taatactctc
     4981 tactaaattt ctaacatctc ttatataaat taactattta ataattcaat cataaatcta
     5041 gctcctgcct taaaaccaag cttataacca agctctcttt caatctctat aactgaatta
     5101 aataaatcat ttaactctat caatacatcc attttctttt cttctgataa atttttttct
     5161 agtaatttat taactttctt aatttcttta catctatcat tataatactc atctttttct
     5221 agtactttcc tatacatgtg ttcatttatc caataatcaa aatatatttc tataatttca
     5281 tcatacatgt tagtacctcc ttgactttca tctggtactt aatatatact taacttgtgt
     5341 agattagtgt acattaagta cctaatttat aaaggtagtt gttatattta tatggcaact
     5401 acctttttct aataaatttt tcaatctaaa tactatatat tttaaatctt cattgcttac
     5461 tattgaggat tatatacttt tcttctaaca ctccttaaac aatagtttat atatcactta
     5521 ataaattata ttttttcata cctcctttac cttcttacat tccttaaaag aaaacaaact
     5581 tcctatatac caataaggtc taaagcctga ttccccatct ctatttttag caactataat
     5641 ttcacttaaa ttagctccaa aacctttttc tctacgtctt aattctttta tatcctctat
     5701 tcccattgtc ttacaataat caagagcctc tttctctgta ggtctatgaa tatatatgac
     5761 tgaattagaa tccatatata tctgttttga acttctcatt actctatctc cttttggcct
     5821 ttcatccttc aattcatcat ttaattgagc caactgtata attggaatat taaagtctaa
     5881 agtaatcttt tttatttgcc ttgataaatc agcaaactta gcttctccaa cttctttacc
     5941 ttcgtaatcc aaaatctgaa gataatcaat tataacaaca tctggtttaa tactttttat
     6001 ttctctctta attcctgata ttgtattgac tgaatcatta atatagagat tattttcctg
     6061 atttaaagta cttaaagcat ttatgtattt aattatttct tcttcattta gatttctatt
     6121 cttcattttt acaactgata ttccagttaa agaagctatg tttctaaaca aaatttgtat
     6181 atcactcatt tccccactta taaaaagtac ttttttacct tgaaatacca catttctcat
     6241 tatctgtaag gctagtgctg tttttcctct tccacttttg gctgctattg taattaattc
     6301 accactatat agacctccaa tagtttcatc taaaaatttt attcctatat cgataccttc
     6361 ttcaatttca tcatttatgt attcaaaggc tctttctgat atagctgtta tactagaatc
     6421 cttcttaacc aatttctgat taacttcatt aacgtatttt tctaattgat atataagtgt
     6481 attatcatct atttcaccta atttgaattt attaaattta tcaattatat ttctattttt
     6541 atatttttca ataactatct caatataatg ggatacatta cctatagttg gaactattgt
     6601 tgatagtttt gtcaaataac ttatacctcc aacataatct ataagcccct ttttctttaa
     6661 atcttctgta agagttatta tatctatagg ctcatccctt ttatgtatat ctttcactga
     6721 attgaatata tgtttgtgct cttgatgata aaacatatct tcacttatta atatctcaat
     6781 ctcttctatt ttcctagaat ctagtaaaat actacctaat atagattgtt ctgcttctgt
     6841 gttcttaact aaattactca tattatccat aatataaact ccctaccact ttaattgtga
     6901 atcatctgga ctatatgctt ctgcatctac tttgacatta attgatttat cttgataatt
     6961 gccttctaat atcttaataa aattatttgg gctcattatc caatcaaaat ttgccttcca
     7021 acctttttca ttgcttccat ttaaaaagct agttttacta actatatgaa taatttctaa
     7081 tacagtctct ttatcatatt cttttattct agcattaatt actttttttc tagcttctgt
     7141 aagtttcttt acttttgata gttctgtaca agtaatattg aatttttcta taatttcact
     7201 gtatatttta cttttttcat tatttacatt cttgttagtt gttagttgct tgttaattgc
     7261 atgttgatta gtctgttgat tttcttcatt agattgatat agctcccagt tttcaatagt
     7321 tataagccta tttttgtttg ttgatttatt tgttagaaat ccatatcttt caaatttctt
     7381 taaagcagtt cttacattct gaatacttac atcttttgaa cacatatttg ctatactttc
     7441 caaagatgtt attaactgtc ctgatttaac ttcatattct ttacctccat aaacccattt
     7501 attaggctta tgattaactg acagtaatag gtttatgagt atatctcttt gtttggaatt
     7561 acaatcttta tatagtgggc tttcttttat ctttctatga agctttatcc aacctagatt
     7621 actcaaatac tatcacccac ttaagtctat aattttatac catttgcatt ttcaataaac
     7681 caattatcta gtttattttt tattatatac actctattat ctatccatat acaaggaaat
     7741 cctttatttt tagaatgaca taactgtcta aattttgatt cccctatggg ataaatttta
     7801 gaagcttctt tacaagtgat aagttgagct ttatctcttc tatatgtctg tatctccttg
     7861 tacccttttt ccttttcttg tgcttcttgt tcttgcttga caagtatatt caatgtagct
     7921 tgtagtgttt taagaacttc tagattattt gtatctgcca tacatcattc ctccttatca
     7981 aaaaataatt cttctacact tgtatctagt tcttgagcca attttaacat caacatatta
     8041 cttggatttt ttgatttacc tctttctaaa gaagataaat aatatcttga gatgccaact
     8101 ttttcagcta attcatattg ctttatacct ttttcaattc tttttaattt gagtttcatt
     8161 gatttcctcc tttctttcat acccattttg tgtatcctca tttctataaa atattctaac
     8221 acccatttgg tgtattgtca atatatttaa gtgtatcaat agacccattt agtgttataa
     8281 tgtatttgag gtgaaattat gatagataat acaattggaa aaaagattaa acaatataga
     8341 aaatctataa atatgtcaag ggatgagtta gctaataaga ttggttgctc agtttatgct
     8401 gtagctaaat atgagcaagg ccaaagaaag cctagtttag atatgataaa aaaaatatct
     8461 actgcattat caattcctat aaataggctt attattgatg aaagtgattt agatacttca
     8521 acaaataatt atactaattt aaaagaattg gatttagttg taaaaacatt tgataattac
     8581 tcagcaaaac tcatcggaaa taatataagc aaatttagaa atataaataa tatatctctc
     8641 aaagaactct cagaaaaaat aaattgttct gagaatgaaa ttataaatta tgagaatgga
     8701 acaaaaatgc ctagaattga aatattaaaa aaaatagcac ttgctactta tactaagatt
     8761 gaagacttat ttggatttcc attagaagag ataaaaatag ataaccaaac aatcctctat
     8821 agaaatcccc agactggata tattatagat aactttctta tcgattttat aaataaagat
     8881 attaacatag ataatactcc agtttcttat tatatagata agtcagaatt tgatttagta
     8941 attcatatat taaaaaatta tggttatgat gtaaaaacag attataagac aaagtttgaa
     9001 attgcagata atgcagatac aataaaacca attagcttaa gcttctctga cttcaaagac
     9061 ttctccaaaa atctaaattg ggtgataaat ggtcttgttg aaaattttat acaagaaaac
     9121 tctaatggtc ttattgaaga tgaggatgaa gaatattagt attgcacatt ttcaaaatat
     9181 gagtttacct attaactttt atacattcat agttaataaa taaaaattag atatgatatg
     9241 aaaggagcta aaatcatgaa taaatcatat ataccaaaat acacacataa attccctact
     9301 aatctacctc atggagataa aaaatatact ttaacataca ttagaagaat gataagtgaa
     9361 tttgtatatg atatgggtaa cctagaaaat aaccccttta cattcccaga agtacaaaca
     9421 ttacttgatg gtataaccgt aggtggacat aaattaagtg accaaaatca aatactaaat
     9481 ataaaatcat catgggatta tgtaataaaa ttaagtaaca aagaaaactt atctttaaat
     9541 aaagatacaa tttgctctat acataaaata gttgcaaaag atgaagctct aatagttgga
     9601 gattttagaa atggtaacat aggtatagct ggtactactc aatatgaatg catagaagcc
     9661 actctattaa atgatttatt tgtaagcgac ataaatatca taaataaaat aactaacccc
     9721 ttagaaaagg ctataataat aaatttatgg ttgtcctatt gccaattctt ctatgatggc
     9781 aacaaaagaa ctgctagact tacctcaaac ctaatactta taagtaatga tataggagtt
     9841 ctatcaatac cagctaaaca taaacaagaa tacaacacat taatgctaaa cttttatgaa
     9901 acactagaag ctgatgaagt tataaaattc ttattagaga aatgtattac attctttgat
     9961 gaatataact ataaatcata taaggagctg tttaaaaatg gcaactaaaa gagctaatgg
    10021 agaaggctct atcggaaaat ataaagatgg ttggcgttcc cgtataatga ttggctataa
    10081 tgaagatggt aaaccaataa gaaaagaatt ttatggtaag actcaaaagg aagttaaaga
    10141 taaacttgat gcttataaaa aacaatatta tttaagctct gatatttcag atgataaaat
    10201 aactttagag cattggtttt acaattggtt atttgaatat agaataaaag atttaaaacc
    10261 taaatcattt gaaagatatg aaagcatcta tcgtaattat attaaagata ctgatttagg
    10321 caatgttaaa ttaaaggact taagagtatc tcacatacaa aaatattaca atagattgct
    10381 tgattccaat aaaagtatac ctactataag gcaaataaac actaaactga aaacctgctt
    10441 atcagaagct gaaaaacaag gtcttataca acgtaattat tgtactatgg taaatatacc
    10501 agttgagaaa aaggagaata agcttgaaat attgactctt gaacaacaaa agagttttat
    10561 aaaagctata gatggacata aattagaggt attattttta cttgctcttg gtactggact
    10621 tagattagga gaattattag gacttaaatg gtttgatatt gattttaaaa agtctaattt
    10681 aacagttaaa agaacccttc aaagaacata ttttatagat aaaaccggaa atagagagct
    10741 taaagtatta gagcaagagc caaagacatc aaattcttac agaactgtac ctattccaaa
    10801 agatgtttta aataaattga aagagcataa agtaaatcaa aattcggata tattaaaggc
    10861 tggagaatta tatagaaatg ataattatgt attttgcaat gaattaggtg cccctattga
    10921 tgataaaaga cctttaagga atctaaaatc tatattaaac agcttagata tagagcctat
    10981 aaaatttcat ggtcttagga aaacttatgc gactagactt tttgagaatg atgtccctcc
    11041 taaaactgta caagttttaa tgggtcatta tgatatatca ataactttaa atatatatac
    11101 tcaagttatg gaagataaga aaattgaagc tgtagaaaag ttggataaaa tattttcatt
    11161 gtaaaaatca aatatataaa aatactctga tttcatatag ttaattacaa aaccaaaata
    11221 aggatacaaa ttaattttat attatcttgt atccttattc ttgtctagtt ttttaaatat
    11281 ttatcttgga tagcctttat gatacattaa tccattttct aacattagtt cttgggctaa
    11341 atatatatga cccttacagt gcatatctga tataccctca cttataagtt tatatgtttc
    11401 agaagtatat aaataatcca tactttcttc caagctctta cctgtttgtt tagaaaattc
    11461 taatatgatt tttttatata gcgattgtaa caatgtctta ttagcttcca taaaagctat
    11521 acctcctctt tcaaatattt gtttatccta ttttgactaa ctatatattt attagttatt
    11581 taattagcca taataattcg gctataagat atttataatc taatctcaat tatataaatc
    11641 tttttgccaa tatttaataa tcaaaatatt gcacttaatt aactatctta taagtattga
    11701 taataaaatc tgtcttctta aatatactta aataaaactt ctataattat atcaaagtat
    11761 taatattcac tctctattgt ctctcctaca agtctatttt ctccatttag ggtatatact
    11821 cctgatatag ttggttgtat gtattttcta tccatatatg gttcttctaa aactcttttt
    11881 tctgctagca tcgtccaaaa tacactatat ccttgttcat taagatattt taagaaaatt
    11941 tccttattaa taaagaatcc tatctcttca ttaagtaatt cactactttc aaaacaaaca
    12001 acttcaccat aatcattata tagaatcgaa tctccctgac catatctcaa tttcaaccca
    12061 taaaatagag tactacaagg tttatgccat gtgccagaaa agtcttcttg aaatatgtca
    12121 ccttctcgtt cagtagtata actataagtt ggcaataata ctttataatc cttttctaag
    12181 atattcttat gttcatctat ttgtacccac tcttctccac aataatatga attttgaaaa
    12241 aagtaatatc catctgccca ataatattcc ttattataaa gagtataatt actattaggt
    12301 tcagtaagcc atctacccat aaagtctttt ccctttagag cattcactat tggttctagt
    12361 tggtcatttt taattatata gctattgatt aatacccaca tgtctttttc aggattttta
    12421 tagttcttat ttttaaaatc attttcctcc ttccaagtat accatccatt aagtaataaa
    12481 aagtcttgat ttttgtaaac actatttacc atatcattta tgcttggtaa atcactaaaa
    12541 tctcctaacc actcattatt aggtattgga gaaaattgaa ataattgatt atgtactctt
    12601 ttattgttat tattatttat tactgtcatg acagttggat caatattcct aatatctggc
    12661 tcaaatgtac ccttacaata aatttctttt ttagtaccat aagcatctgt atacacttct
    12721 atcttataat tatcagcagc ttgcgctgca agttcatata atgcaatcca ttgatatttc
    12781 tttcctattc tttcatattt actatctctt aatctaccat tttgtactgt tctatcaaat
    12841 ttaccatgtt tatttacatc atatcccata tcaaaaactt tcttaatagc tatattcttt
    12901 aaatcgttat agtctagacc tttccattta tggaaatagt gttggaacat atatcttcca
    12961 aaatctccat accatcctgg ttgtccatct ctagtatatt ctacttccat agaatttaag
    13021 atagtgtttt gactccaata ataatcttta aaatctgatg ccttatagtc atacttatat
    13081 ccctcaattt cttcatcagt tggtacttta ggaaaaattg atttatatgg tggttcaaca
    13141 ttcatatctt ttaatactga actatcaatt ttatattttg cataatctac aatatttttt
    13201 gcataatctc ttaataaaat attgggataa acataatcta catcaaatat tttattataa
    13261 acataaactg ccaatgcctc tatcatctct tctgattgct ctgatacaac acatccaaat
    13321 gcaactgcat ataatcgttc aataatatat gggtcatcta catcttcaaa tgttttaagt
    13381 aaatctatta caatatccat tttccctgtt aatagattta caagagcttt tgtactttta
    13441 tctcttaagt ctctatttga agaaattaaa aacgttgcaa tcatcatagc tgacaatcta
    13501 attgtttcat ttgaagtatt atcaaaacct tcaaaatcaa agcaccatcc taataatcgc
    13561 ttaatagaag actcttcttc ttcataaact tcattaaata taggtataaa gatagcatct
    13621 ctatctgcca tagtattttg taaaatatat tttactatat aatctgcatt taatgtatga
    13681 ttaacctttg tagaaattaa gataagtaca ttataaaaat ctattttata ataagattta
    13741 cctaaaacta ttttattaat ataatctagt gttttttcag taattgtaga tttcttacgc
    13801 cattttagtg cattgataaa tgcactaata acattataat ttgtttcttt atttttaaaa
    13861 acttcaaaaa tttcattagg tatatctgag cctgtctctt cagataaaac aattgccaat
    13921 acttctaata tatcctcata ttctactaaa tatttatact tatgtgaaaa atctactacc
    13981 ccaatttctt ttaactcttt aaccaacaaa tttgcatata aataatcttc taacttctca
    14041 tatgtcacat gcatatattc ttcatcattt aaattgactg ttttattaac tattccattt
    14101 gctatgagtt catctattat cacattgtta atcttatact tacttgcaat atttattata
    14161 atctctacac tcttgtttgc gggtattaaa ttattcccaa gaccatctcc atatttatat
    14221 ttaatcattt cattaagtac ttctgtaact acattggcat gtctactata attgcatgat
    14281 tcagatattc taagattaag tatattcaaa taatttttat aaatatctgt aaaactaata
    14341 gtatctaagt taatctcttc tcctttaaaa gtttcacaca taattctcaa aaaaagaggg
    14401 tttctaaatt cttgatttgg cattggaata ttagaataag gtattccata ataatcaaaa
    14461 tactttttca tagctttatg ttctatacta gaaaatcctt gatgctctat aaaaaccaaa
    14521 ttctctttta tcttgttatt attatctatt aaagatggta tatattcact tcttattgat
    14581 aatattagtc caatccatgg atatttcttt atctgttcta caataccatt taaataatat
    14641 ttccaaagtt cttttccttg accttcattc aatgcatcta taaataatat cacacgctgt
    14701 tgctcttttt ctcctatttc attaagtatt tctaataatt cttcaaactc acactcaatt
    14761 tctaatattt ctaacatatg tttaattggt gttttatcca acttaaaatg ttgccctaaa
    14821 aataatatag acttatgccc atccatattt cttttctcaa tagtatgtgc aattatatga
    14881 gatttcccca taccacctgc actatgtaat aaaatataag ggctattaac tacttttatt
    14941 tccttagaat ccaaatattt tatatataca tagatatctt tttgagtctg cttcaatttg
    15001 tatatttcat cttctctttt tttacttttt tcacagtctt catttataat tatattttta
    15061 aaattattta ttctatcatc aagtgctgca cttatttttt caaagtgctt ttttaacaac
    15121 ttgatatcta atctttcatt agctttgtca taaaattgtt gtattatttc ttctataact
    15181 agtacatcta cttccacttc atttattttc tgtttcttta tacttgatag aactttatct
    15241 gttttttcat caaaacgttg tttaaattct tcattttttc ctaatgcatt aaacgtattt
    15301 tctaaactca attctacatt caattctggt aaatatctat ctccaaggtt ttttatctgt
    15361 atattattct gattttgaaa ccatttctct gttaatctac aagataaatt agttaaccta
    15421 ctttccttta aagacctatc ctttaatctt ctatattcat ctggcaaaac tatttccaaa
    15481 attcgttcaa gtattattct tacacactca tgcttacctt caggatacat aatggtttgt
    15541 atataatact cattttctaa ctctattcgt ctatgtttct ttttctcact actaactgga
    15601 ataatagcat aatgacccgt tcctgcctct gatacttgct gtaataattc caacggtcta
    15661 tccttttcca aactacatcc aagaaataac aactctttac ttgtatatac ttgtgtaagc
    15721 atctttctca attcatcatt actatatgct ttttcatatt gttcttttgt taacacaata
    15781 gatgttgtag gctctgtaat atccccatga attttataca atactaattc attatttcta
    15841 agtgcattat ttaatgcttc aaagtgacct ggatgtgaca ctaaaactgt tttattgtgt
    15901 aatccataat ttttttctag tactttatca taattagtag ttataattaa tcctgagcca
    15961 aaaattatag gaattaaata gacacattta tcaataaaat cgtctttatc ttttgcatcc
    16021 agataacctg ccccaaaaac tttttttaaa tgtttagaaa atctaacttt cgccaattct
    16081 tcatataaaa attctgcttt tttctcataa tcctctattt tttcaaataa aattttatcc
    16141 tcatcttcta aatattcttc acttgtgtta tttaaaaatg tactccatga aggatatatg
    16201 tctttaaata acatagacat gcctgctcca atatatggga ctacataacc atctttaatt
    16261 gcatttacca gttcatcaaa atttttttga ttgtaaggct tattaaattc cataatttct
    16321 tcaaatgtca ttattccctc ctaaactatc tcttaataat ttcaaccata attcctattt
    16381 tataatttta ttatatcatt ccattccatt tttttactac aattctatgt tatagaatga
    16441 attcacttac ttacatttgt taataatata aaactttctt ttaagataat taaaatttat
    16501 acttttaaat tatggataaa aatggaatgt tataactttt aatgtattac taatattaac
    16561 aattttaaaa aataatacta ttcttatttt atgctataat tatattttgc ataaatatta
    16621 ttgatatttt ataaatataa ttatacttat atctcatact caaatatttt atataatata
    16681 taagtctaaa ttaacttgca atataaaagc gcctcttaat ataggcgcta taatgttata
    16741 aatttttaat tatatattcc aatgaacctt tatcaaccat atctaaatta aatatataat
    16801 ccatcttatc aaatgcatct cttaatggaa tacttgattc aagccatcct aacccatctg
    16861 taatccaaca aaatgtaaaa cctccatctt ttatatactt atctaactta gtaaactcat
    16921 ttgcaacaga ttttaactta gaacctccac cattataaaa attaacttct actaaaacaa
    16981 tttttccatt attatttata gcaaagtcat actttctttt actcttatct gttggaactt
    17041 ctatagacca tttctcactt atttttttca ctgtagcttg tgttaaataa ctccaattat
    17101 tcttttcaca catattcttt acatatcttt ctacaagagt ttccatacta cttccagttc
    17161 tattttttct agcattcgta tcaagcccaa cctctactcc aaacacataa tctactaaat
    17221 tttttatatt tttttgtttt aataaatcta aaaactttat ttttttaaga aattctgtag
    17281 ctaattcgct ttcttcatca cttatactct ttctcttctt aaaattaaac agtttatatt
    17341 taaacatatc ctcatctgat ggatctagta ttttgaattc attatctcta ctcgctatta
    17401 ctattggtat cacactaaga acttctggat actcttttaa taaattttta gtttcgtttt
    17461 ctatatcttc ttttcctata agatagttta agatatttaa ctgaacctct atctttctag
    17521 tattttccaa agctttattc cagttaacat aataatccca gctagctata gtacctttta
    17581 aattttcaag taattcctta aatatttcat ccttactctt atttttatga atattcttaa
    17641 ccaattccat ttgattcccc acctcttcat aattagtaat tagcaattca gttataaaac
    17701 ctcttccatt ccccttagaa tttatgaatc ttttagcatg tactcttttt atattaaaat
    17761 ctgaatacaa atcatcaaag aaagtatctt cttcatctaa aacttttgga tcagaattac
    17821 ttaacatcaa ttttgtatct attttatcta gaactttata aaatttactt aactcaattt
    17881 gactatcatc attaaaatta cctttgttat aggaattaaa tcctcctata gttactggtc
    17941 tatatggtgg atctagatac acaaaacaat ttttatctat tatattttct agatttaaat
    18001 aattcttatt taatattttt acttttagct ctcctcgaga atctctttta tttaaaagca
    18061 tggataattt ttcaagttca tttttatcaa aaaaactagg atttttatat cttccaaaag
    18121 gtacattaaa ttcacctcga gaattttctc tatataatcc attaaaacat gttttattta
    18181 aaaatataaa atatgaagct tgctttatac aatcttcatt ttctatattt ttttcatttg
    18241 taagtatatt aaatctatct ctaatatcat agtacatctt ttctctatct gaagaacctt
    18301 cttcgtaaga tatgtattgt tcttttaaat tagttagttc tgttattaac tcttccaaat
    18361 catctctgac tttaatatat aaattaatta acttactatt tatatcatta attacatact
    18421 tgttgaaaat gtcctcttct aacaaatata gaaatagtgc acctgcacct acaaaaggtt
    18481 ctatataagt catggaacta aaatcacaac ctgtaggcat ttgttttctt agaatatcaa
    18541 gtagctgtgt tttacctcca gcccatttta aaattggttt catgcaacac ctctctcagt
    18601 tatattgtta tataattata taaaataaga ttctaaaata caagtactca tcagaacact
    18661 atatttatat caaatctttc caaaatctaa gtattatttt atcctaacac ttttcaaaac
    18721 ctctaaataa tatacaatat tctctaatat ttacttacta aaaatttaaa tctatcttta
    18781 agtataacct aaaacagatt ataagttacg tagtttttaa tataaaatat acttctacaa
    18841 gtaaagcttt aaatatcaat tacttatttc ataattaatg actatgtacc ctcaaaaaaa
    18901 cctcattttc tatggttggg gtacggttgg tggatttcat caccaaaata aaaaatacta
    18961 gtcaataaag actagtattt ccaagtattt catcattctt ttttcaaaat tggtggagac
    19021 gaggggagtc gaacccctgt ccgcaaatct tttccttgct gcatctacat gcttagccaa
    19081 cttcactaat atctcacctc acatagcgcc aagtggcagg ctctatgctt agccagtccc
    19141 aattaatcta cttcaggtcg agacacccct aaagtagttc cctgcataat gacgtccagt
    19201 cttagtcggc aggaggacta agagggacga gcagcaacta ggctgctatc gcgaaattat
    19261 cgtctgcgtt tattttaaag ttccccagtt tttacgtgac ccagagtaac acgacatgca
    19321 gcctcaagtt ccaaacccac gtcgaaacct ttacgccccc ttgagtagtt tatagtccag
    19381 tagacttttc gcaaacttta tcaccatttt tattaaattt ttaatgtata tataatataa
    19441 tacttttaag aataaaaatc aatgttatgt tctagataat aaagaatttt attctaaaaa
    19501 atacagtttt atctagttta atacttacct gtcatttctc tttctatacg tctttgtgca
    19561 tctttcttag ccatatcttg acgtttatca tatagttttt taccttttgc taaggcaatc
    19621 tctactttaa ctttaccgtt ttttagatac aaactaagtg gtataagtga ataccccttt
    19681 atagtagttg ctccaataag ctttcttatt tcatgcttat gaagtaatag ttttctaact
    19741 cttaaagaat caacattgaa tatatttcct tgctcatatg gacttatatg aacttgtttt
    19801 aaaaatactt cgctattatc tacagatgca aatccatcac ttaggttaac tttgccttgt
    19861 cttattgatt ttacttctgt tccttttaat tcaattccac attcataagt ttcttctata
    19921 aaatattcat gtcttgctct tttgtttgtt gctaatattt ttttaccagc catataaatc
    19981 tcaccttctt tgctagaaat ttattccata aatattagaa atttactaaa tatttaatgt
    20041 tgccaaatta tttgactaac ttgtatgata acatatttag gcattttagt caatatttca
    20101 ctgatatatt aagttagtta ggctatatat aattaagtaa tataaatgta tgaaaatagc
    20161 taaaaaacta cttcgaatat acttaatact aaactaactc taaccagtaa tactaattta
    20221 taaatttcaa aacaaaaata ttacatatta ta
//
LOCUS       DAYAKB010000065        20091 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.065, whole genome shotgun sequence.
ACCESSION   DAYAKB010000065 DAYAKB010000000
VERSION     DAYAKB010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20091
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.065"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..1088)
                     /gene="asnB"
                     /locus_tag="ACGI3L_002788"
     CDS             complement(<1..1088)
                     /gene="asnB"
                     /locus_tag="ACGI3L_002788"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFG9198485.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVA"
     gene            1261..1965
                     /locus_tag="ACGI3L_002789"
     CDS             1261..1965
                     /locus_tag="ACGI3L_002789"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFG9198486.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVV
                     NWNGALENYKNLKSQD"
     gene            2078..2614
                     /locus_tag="ACGI3L_002790"
     CDS             2078..2614
                     /locus_tag="ACGI3L_002790"
                     /inference="COORDINATES: protein motif:HMM:NF016214.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFG9198487.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(2780..3400)
                     /locus_tag="ACGI3L_002791"
     CDS             complement(2780..3400)
                     /locus_tag="ACGI3L_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFG9198488.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(3714..5852)
                     /gene="vanT"
                     /locus_tag="ACGI3L_002792"
     CDS             complement(3714..5852)
                     /gene="vanT"
                     /locus_tag="ACGI3L_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HFG9198489.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(5870..6676)
                     /locus_tag="ACGI3L_002793"
     CDS             complement(5870..6676)
                     /locus_tag="ACGI3L_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9198490.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(6673..7773)
                     /gene="vanG"
                     /locus_tag="ACGI3L_002794"
     CDS             complement(6673..7773)
                     /gene="vanG"
                     /locus_tag="ACGI3L_002794"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HFG9198491.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(8034..9116)
                     /gene="vanS"
                     /locus_tag="ACGI3L_002795"
     CDS             complement(8034..9116)
                     /gene="vanS"
                     /locus_tag="ACGI3L_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFG9198492.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            complement(9166..9867)
                     /locus_tag="ACGI3L_002796"
     CDS             complement(9166..9867)
                     /locus_tag="ACGI3L_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-G-Cd"
                     /protein_id="HFG9198493.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(10301..12832)
                     /locus_tag="ACGI3L_002797"
     CDS             complement(10301..12832)
                     /locus_tag="ACGI3L_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9198494.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(12940..13557)
                     /locus_tag="ACGI3L_002798"
     CDS             complement(12940..13557)
                     /locus_tag="ACGI3L_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFG9198495.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(13919..14803)
                     /locus_tag="ACGI3L_002799"
     CDS             complement(13919..14803)
                     /locus_tag="ACGI3L_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFG9198496.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(14994..16244)
                     /locus_tag="ACGI3L_002800"
     CDS             complement(14994..16244)
                     /locus_tag="ACGI3L_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9198497.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(16466..17230)
                     /locus_tag="ACGI3L_002801"
     CDS             complement(16466..17230)
                     /locus_tag="ACGI3L_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198498.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(17224..17949)
                     /locus_tag="ACGI3L_002802"
     CDS             complement(17224..17949)
                     /locus_tag="ACGI3L_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198499.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(17951..18319)
                     /locus_tag="ACGI3L_002803"
     CDS             complement(17951..18319)
                     /locus_tag="ACGI3L_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198500.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(18495..20039)
                     /locus_tag="ACGI3L_002804"
     CDS             complement(18495..20039)
                     /locus_tag="ACGI3L_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9198501.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         6904 a         3455 c         2048 g         7684 t
ORIGIN      
        1 aatgctactt taacatgttt acctgcctct ttaattaaga aataaagacc tacttctgaa
       61 gggtctgcta tagggtcatc caaagaataa attacattcg gtaatgattt tatatattca
      121 tcttgtgtta tattaatctg gatattttct atacctaact tatcagctgt tttctttgct
      181 acttctaatt cactatatcc tttgacacta aagcctgcag aaaaagattt tatatttgga
      241 ttaatttgtg aagccacagt agttataata gatgaatcta ttccaccaga caaaaatgtt
      301 ccaatttctt tctcctcttc catatgagtt actattgaat ctactactat atttcttata
      361 tcatcctcat tcacatctct attgcctaag tgatttttag tataaaaaaa ttttgtacta
      421 cttctaaact caagtttatt atatctcttt aaagatagta taccattttc taccctaaaa
      481 tagtgacctg ctggtatcag ccttattcct tgtatcatag tatcttcagg aagtacatat
      541 tgaaatgaaa aataactttg taagcttctt tcatttatat ttaaattttt catatattca
      601 agtaaaaact tatactctga ggaaaaaatt attgcatttt ccttatttat ataataaagt
      661 ggttttatcc caaataaatc tcttgctcca aatatacttt cattttctct atcatagatt
      721 ataaagttga acattccttt aatcttatgt acacaattct taccaaattc tatataagat
      781 gctaataaga cttcaatatc atcatttgta gtaaaattgt gtcctttttt aattaattct
      841 tcttttattt catgatagtt atatatattt ccattaaaaa caataacttt tccatctttt
      901 tcaaatggtt tatttccata aatagcatca attacattaa atctttcaaa atcaaaagtt
      961 ttttcctcat ccttatactc tattctacta gaaagtcttg tattatttac agattctttt
     1021 attttaaatt taatatcttc ttttttagat atatcacctt tataataaat tgaaatattg
     1081 ccgtccatat aatcaaaatt cctttctgtc ctttagtctt attctatatt tcatagtttt
     1141 gtctttggct ttaaaactta ttcaatttaa aatgaaattg ctattaaatt cttataaatt
     1201 atctgttaat atttcatatt ttttttattt ctagaaatac tatattagga ggtgattttt
     1261 atgaagaaaa aaatattaat accagttatt atgtctttat ttataatctc acagtgcata
     1321 acttcatttg cttttacacc tgaaaataac aaatttaagg ttaaaccatt accttatgca
     1381 tatgatgcac ttgaacctta tatagataaa gaaacaatga aactgcatca tgataagcat
     1441 tatcaagctt atgttgataa attaaatgct gctcttgaaa aatatcctga gctttataat
     1501 tattctttat gtgaattatt gcaaaattta gattctttac ctaaagatat tgctacaact
     1561 gtaagaaata atgcaggtgg agcttataat cataaattct tttttgatat aatgacgcca
     1621 gaaaaaacca taccttctga atctttaaaa gaagctattg atagagactt tggttctttt
     1681 gaaaaattta agcaagagtt ccaaaaatct gctttagatg tctttggttc tggttgggct
     1741 tggcttgtag ctactaaaga tggcaaatta tctattatga ctactccaaa tcaggatagc
     1801 cctgtaagta aaaacctaac tcctataata ggacttgatg tttgggagca tgcttactat
     1861 ttaaaatatc aaaatagaag aaatgaatac attgacaact ggtttaatgt agtaaattgg
     1921 aatggtgctt tagaaaatta caaaaattta aaatctcaag attaattaaa tattaaaatc
     1981 cttttgaaaa aaacttatgt ttgctatata atataataaa agatagtcta aatttaccaa
     2041 tataatgttt atagtgacga ttcaggagga tttttatatg ataaaagaaa cacatgaaag
     2101 gggaggttat atattcgcac ttttgatact cccctttata aacaatctat acctagttaa
     2161 atacgatatt gcatataaaa tagtattaat tataatttat atttattttg catatttagg
     2221 ttctttattt ccagatatag atatgagagg ttcttacata agtaaaaaat ttatgttaat
     2281 atacaaatta tttggaagta ggtttagaca tagagggttt actcacagtc taattgcctt
     2341 attacttatt tatagttttt ttaaatctct gacaatcttc actaacaata atatagtttt
     2401 ctcatgtttg tccagtgggt ttataatagg atatctatct cacttgtgtc ttgaccttat
     2461 tactaaagaa ggtattgaat tgttttatcc cattaccata aacatttctt tactacctat
     2521 aaaaactaac tcaaaaacag aaaaattcat atctaagcta ttaaatttca tagttatttt
     2581 tttgattgga tatcaatttt atattttatt atagttgtag aaaaaataaa taacaatatt
     2641 ttgaactaag tataaataag ttttatatat tttagtttac aaaagaacta aaaattttgt
     2701 accttaatac aaaaaataaa acgtatctta aaataattta gtactaaatc attttaagat
     2761 acgttttatt tcgtacaagc taaatcattt tatcatcttt atcattgtga tgttttttat
     2821 gatggaaatc ataattatga ttttcaagat ttttatttac tctatttcca atcttccatg
     2881 acaaaaacac caataatata aatgatgcta tctttaaagg acttgttata aaaccttcta
     2941 tatcacttgc cacgtaactt ataactataa acattacaaa ttttcctgcc aacattgctg
     3001 gcacaaaatc ttttaaatct tttttaccaa aagctgatgc gatagtaact aaacaaccgg
     3061 gcataaatgg acaggcatac gctataaata ataacttaaa tccctgttta tccatccaac
     3121 ttattgcttt ttcagtttta ctatttctca acttattaaa aagcttacta tcattaaatc
     3181 tgcttattaa taagaataat gaagttgtcc caagtcctga gccaatccat gataacaaac
     3241 atccaataaa taatccttgt attgcagcat ttgctgtaac tatagcaaca agtggtaagg
     3301 ctggtataaa gctttctata aatgcactta ataagccgat tattgtggct aacacccaat
     3361 aattttgagt caaatcaagt agttcttgta tatactgcat attgcttttc ccctttttta
     3421 actttaacta ttattatata ctctatatgt ttattatata ccaatctcaa aaaatgaatc
     3481 taatattaaa aagtaaataa tctatataag tttacagtta aggtataatt attttattat
     3541 atattataac aaaaaaggtg atgtttcaaa ataaaaatct gaaacatcac ctttttataa
     3601 cttaaattgt catgtaagtt ataaaaaata tatattagac ataatattac taaaaatgtc
     3661 tagtcagagt aaaataaatt acacagtaca acaaatatta ctatttaatt gagttacttc
     3721 tttataacat ttaaccttct tcctactctg ctcaataatt cattcgatat actacatgag
     3781 ttatttgcaa cttcagaagc agataattca gataaattat ctcttcctat tattattgcc
     3841 gtattaccaa cttctacatt aggtatatct gtaatatcaa cagcaagttg gtccatgcaa
     3901 attcgaccca ctattgctgc tctacaacca tttattatta cgtaactttt tccacaggat
     3961 aaatttctag gtataccatc ggcatagcca atagataata tagcaattac gctatctctg
     4021 cttgcaataa agactcttcc atatccaaaa ctatcatctt tttgtatttt tctaataaga
     4081 attacttgtg attttaagga taaaacaggt cgtaaatcaa gttgcaattt agtcgtatca
     4141 tttggagaac ttaatatccc gtataatgca attccaattc ttacataatt acacttaaga
     4201 ttgggataat taaaaaaacc ataactactt tgaatatgta ctttaggaat ttttatacct
     4261 ttttttaaca gaaaatcaat taacttataa aaacattcaa tttgtttatt tgtaaagtct
     4321 acatcttcat ctttcagact atctgaaaca cacaagtgtg taaatatgcc acatatatct
     4381 aagtatttta atttaaatgc ctttaaaatt gacctcacat cattaacatc aaaacccagt
     4441 ctgtgcatac ctgtatcaat tttaatgtgt gattttatgt tgtatttctg tttgtttaaa
     4501 gagatagcat gattaaggtc aataacactc tgtgtaagat tgtatttatg aagttccttt
     4561 gcccttattg ggttagtata tccaagaatc aatatttctc ctagtattcc atatcgacgt
     4621 aaatcaatcc cctcatctat tgttgctact gcaaatgctt ttacacctat ttggtttgca
     4681 caagtcgcta cttcaaaagc actatgacca taggcattag cttttacaac tgccatcaat
     4741 tcacaatctt ctggcatagc tttttgtatc atctttacat tatgttccaa attatttaaa
     4801 tcaatttcaa tccaagctct attggtattt accttatgtt ctcctttcaa gtcttttttt
     4861 agaggtttaa gaatcaatat aataattata gaagctataa aagatgctat acttaccact
     4921 atataatgaa taaggctatt gtcaaccaag acagtttgta ttccgaatat tttagaaaac
     4981 atacgaataa caacaatcat cataggatgt ataatataaa taattaatga tgatgttcgc
     5041 aataacctag ctcgagaacc tttcaaaaat gttaaggctg taaataagaa atacatacat
     5101 ggcaataaca taatatacat gctatcatga cgctgtaccc ctagtttatg taaaaacatt
     5161 ccctcacata acataagtaa gaatgatata agaaatccaa tcaagctatt tttagttgac
     5221 atataattag atttattaga tattattcca ccaagtatga aaaatacagg tgcaaaaaat
     5281 ataccatttc gtgtataatc tgatacttca aaaatatacc catataaatt ctttaatagt
     5341 ggtatttttt ctaaaaaacc ataataacta tcaccaaaca taccaattac ataaataaca
     5401 atagtgatta ctagtgagta ctttaaacct agtcttttta caagaaagta tgcaatactt
     5461 gcaccaataa ttgatgcagg tagataccat aaatgatata aagtcccatc aaatacaatg
     5521 tccttaataa tattgggcac taaattattc atggaaaaat atccagtgta aatatttaag
     5581 ggaatataaa ttacaatagc tatcccgtaa ataaataata cattttttag aaaagatttc
     5641 agtttattac aattataatt atatgttgaa attagaaaaa agcctgatag cataaaaaag
     5701 aatggcacag caatacgagc aattatacta gttaacacaa agtcagccat tttactatat
     5761 gataataatg gagatgtatg aattgcaatt ataagtaatg cagctataat cctaaaataa
     5821 tcaagccctg cataagattt attcctaatc attcttgttc ctccatttct tagtcctttc
     5881 tatttctcca aaatgtcaca ataaaaccat ccttattgtt acccgatatt tgatatacac
     5941 attgttcagg tatagagatt ctcacttctt ctttagtatg aataggcaca taaaagattt
     6001 ctataatttt ttctttatct tctattttta aacaatttgt atacgaaaat ctcttaatat
     6061 attctatata ttcttcaaga gcgagattca ttttattgat aatctcagaa tgcggatatc
     6121 ccacataacg aaaatgccat ggttcttgag atattcctgt tatttcttct tttttacact
     6181 gataacgctc tataaaacca taatgtagtg ctgccttacg aaactcatta caaataccat
     6241 tataaggaaa ttcagggcag ataaaatcta taacttcttt ctttaaccct aaatcaatag
     6301 caagccctgt ctgatgttca ctgtgatttg gaagtgctac aaacttttta gtaaagtctt
     6361 ttccattgtc acgcagagaa cttgaatata tatcttgttg ttcctctgca gtacgatatc
     6421 cacttacagg tactatttca tttattccac atatactttt taaaatattt tgtaaaatgt
     6481 ttgtagcttc acgtttcata agaatacttg gaaaccttgt atctacagga attaaatcta
     6541 tatcttcaga tgttttaact ggtaaaaaag catttactag aattagattc ccatcataaa
     6601 ctttatcttt agtcaataag atagtatttg tcattttatc ttctttattt ttatctaata
     6661 aaatattatt catcatttta tgtacacctc aattatcttg tccaatattt cttcaaaaga
     6721 caatccaata cctttcatca tatttggata acgactatga gaagtaaagc caggaattgt
     6781 attgacttca ttaaaaataa tttcaccaga tggagttaaa aacatatcta ctctagcaaa
     6841 tccagaacat ccaagagttc tataaataat ttttgctgtc tcttgtattc ttttctcaca
     6901 atccaaatca attctagctg gcatatgaat ttttgaactt ttcaatgtat atttttctgt
     6961 ataatcaaaa aatccttttg acaattctat ttcatctact cttccaacaa gtaagtcatc
     7021 gtttcctaaa actgcacacc ctacctcaaa accatcaata ttttcctcaa ttattacttc
     7081 attatcatgt tcaaaagcca agtctactgc tacttgtaac tcttcttttt tataaatttt
     7141 actaatacca aatgatgaac ctgcacgcac aggttttata aataatggat aagttaagtc
     7201 ttttgacagt tcagccacat taaatttatc tgagtatttt agtaatattg attttggtac
     7261 tttaatacct tctgaatgaa caagtttatg tgatttgtct ttgtccatac ataatgctga
     7321 agaaagagta ccacatccta taacctgtat acctgccaat tcaaataacc cctgcactgt
     7381 tccatcttct ccattttttc catgcagtac aggaaacaca aaatcaagtt tagtgtattt
     7441 aatatcattt tcacatgatt caatagcact atttggaata tgattctgag aaacagcatc
     7501 aggaattaaa aattcaataa taccattttt gacacggttc tgcgaaacaa taactggaat
     7561 tatatcagta tccctttcaa accaagtgtt attctggata ttattataat ctccaatata
     7621 atgataccaa ttaccctccc ttgtaattcc aattggtata atatcatatt tttccgtatt
     7681 caaattctca agtactgcaa aagctgattg taatgataca tcatattctg ttgagtttcc
     7741 accaaatata actgcaattt ttttattatt catctttgat tctcctttgt tgatttattt
     7801 atttttatac aatctacaga aacatgttaa aatacttttt ctatttcaaa tccaatcaac
     7861 cttcacttac aattgcatct gttccacata atatattttc acatttttct attgatataa
     7921 ttactgtatc aaaataaaag cactcttgtt ttgatacagt aattatatca ataacaagag
     7981 tgctctttat ttatttatcc taaagaattt cctatttttt tatacttaaa ttcttacaaa
     8041 tttcctacaa tcggaataat aaccttaaag ataattatat tgttctcgct atgagctgtt
     8101 attgtcccgt tatgaagctc cactatttct ttagctatag caagtcccaa cccagctcta
     8161 ccactgtttg aattacgaga tgtatccaac ctgtaaaatt gttcaaaaat acgctcaagt
     8221 ttttcctctg gaatcgtatt gctatgattt ataaatttaa gctttatata atcatcctcc
     8281 tgtacagctg ttatttcaat agtagtatct tcaaaactat aataaacagc atttcgtaat
     8341 aagttatcaa atacacgttg cattttatta acatcacacc ttatcatcat atttggtgta
     8401 acattcagtg tatattttaa attcttactc atcaaagtag gtttaaactc atatgttagt
     8461 tgttcaagca tacgagttaa gcttactgta ctgtattcaa gtgatatatt tgataaatta
     8521 aaccttgtaa tttcaaagaa ttcattaatt aaatcttcaa gacgctctgc cttatccaac
     8581 gaaatagata aatatttttt tcgcagttct tcagaaatct gactttcatc tcgaagtagt
     8641 gtcagatacc ctataactga tgtaagtggt gtttttaaat catgtgcaag ataaacaata
     8701 agttcattct tacgttgttc tgccatttgt gtctcaaatt tacgttgttc aagtatatgt
     8761 ttaattgagt ttattttctt ttctattgcc aataactctg gagataaagc cacttctcca
     8821 acatcttctt tgataagaga gtcaatacct tgatttattt cactaaaata ttttgtaaac
     8881 caatttaaat aaacccggaa tattataaaa aacacaatca ccatagctag tatcatgaag
     8941 agctccatgc tattacggaa aatctgctga tataaattca atgcagcttt atattccata
     9001 cgaaaagcat tttcaaagaa tgatactatc cagatagaaa acttaccata caatataaaa
     9061 gaatataaaa tccatatgaa aataatggct ataaatgcca ttaaagctgt tctcataaaa
     9121 attttatttc tcacttgagt aaagtcagga ttgactttaa tatttttact tttcaattgt
     9181 ataacctact ccccatacag tttttataaa tttcgggttt ttagaaggtt catgaatttt
     9241 ttcacgtaat cgccctatat gagccataac tgtgttatta ttatcaagat atttttctcc
     9301 ccatacagct tcaaacaatt cttcagaagg aaccactttt ccttgatgtt cacataaata
     9361 ccaaagaata gaaaattcaa tcggtgttaa tgctacttct ttcccaaata aactacattt
     9421 atgtgtttct ttattgataa tcaatccttt aatatcatac tcattaacaa ttatcgactg
     9481 ttgttcataa gaattattat atcgcatata tcttcttaat tgtgtcttta ctcttgcaac
     9541 aacttccaaa gggttaaatg gctttgttat ataatcatca gcacctatgg ttaaacccat
     9601 tatcttgtct atatcttcaa ttttagctgt taacataatg ataggataat agtatttttc
     9661 tcgaattttc tggcaaatat gaaatccatc aatatcagga agcataatat ctaaaatagc
     9721 catatccaaa tttttagatt caatacattc tagagcttcc ttacctgtat aaaacttgta
     9781 tactgtaaaa ccttcatttt ttaaatatac ttcaattaaa tctgctattt ctttttcatc
     9841 atccacaatc aaaatatttt cgttcataga ttatttttca ctctccttat tatcgaggtc
     9901 atcatttata atattggtaa atttacatat caaataatta caagcatatt tgtaactaat
     9961 ttttataaga aaagaactac tacatcagaa tgtgttgatg ctactattgg aacacaaaaa
    10021 ctgagattaa ttgttattat aaaaactccc ctaacacgtc cttattatcg cataacaggt
    10081 attaactttc aataaaaata tctatcagtc aaacacaatt caatttatta taccagagac
    10141 aatccatata aaaaacaatt aaacctatgt atgtaaccac agacattact aaaatttcca
    10201 tgttatttta tataaaaatt caaaaaagga gttgaattta aaatttgatt agaaaaaaat
    10261 caattttgag acaactcctt tttattttaa tgtatttaaa ttatagtata tcagccttca
    10321 taatatcctc aaaatcacct ttttcagata ttaatcttat caatttaaca gtacagctta
    10381 aatcatttat aagtatagct ccaactaatg aaccatcttt cataaataat tttttatata
    10441 ttctttgacc ttcatctttt gatgaaattt ctttatcaaa attttgtata ttaccaatac
    10501 taaatacttt tacattcatt gcatctaatg aaactggata tacttcactt tcaaatgtca
    10561 aattatctcc acttgcattt gcccctgcta tttttcccat ttctactgaa gatggccata
    10621 ttgctaaact aatatttccc acttgtgcaa catctccaca agcatatata tctttaacat
    10681 ttgtctgtaa tgtcttatct acaacaatac ctctatcaat ttttacagat gtatcctgaa
    10741 ccatttgagt gtttgctctt acaccaattg aaaatactac catatcacag tcgacactat
    10801 ctccatcttt aaatacaact ttttgagctt ttccatcacc ttcaatacca tcaactgcta
    10861 cacccaatct tacatctatt cctgtatctc ttacacattg ttctaatatt ttactacctt
    10921 ctttatcaag ttgttttgat agtatgctat ccatggcttc aactactact acttctaatc
    10981 cttttagtct aaattcccat gcagcttcaa gtcccaataa accgccacca atcactacaa
    11041 ctttcttaga tttttctagt gcttctttta cactatataa atcttttata tttctaagag
    11101 taaacacatt ttctaaatca tggcccttaa ttggtggtat aaagtttcta cttcctgtag
    11161 ctattacaag cttatcaaat ttaatagctc catcattcac tataatagtt ttattcactt
    11221 catctaattt atctacattc gttcctaata ttactactat attattttta tcataccaat
    11281 ctttatcttc catgtagaaa tctgaaccaa gttcttcatt tataccatca gaaagtgcag
    11341 gtctatagta agtcaactca tcttcattag aaatcatagt tatcttacaa gttttatttc
    11401 tttttcttat agcatctgct gcataaaaac cagctgctcc atttcctact attacgaaat
    11461 attcatcagt atcttttcta aaagtaactt catcttcttc aacttctata aattggtctt
    11521 ccttagctcc acatacaggg catacactag gagcactatc accttcaaaa acttcattac
    11581 aaattacaca tttaaatttc ttagttttct ttttacttcc aaaagtagaa tttaacttat
    11641 ctaggaattt acctgtataa gaatataatt tatcaatctc ttcatttgat ggtttaaagt
    11701 taacagcaaa aggttttact gctgtcattc taagctgact tattctctcc atagcatttt
    11761 ctataccttc tccactccat ccatatgaac caaatactga agcaactttt ccaccatgaa
    11821 gaactgggtt taacgatatt aatatatccc atataggctt taacgcatct cctaatattg
    11881 ttggtgttcc aaataataca ccttgtgata ctgctatttt tgccaaaata tcttcttgct
    11941 tatgctctat tacatcaaat aaatttactt tatagttgct atttttttca atatatgctt
    12001 ttatagcttc tgccataatc tttgtatatc catgtgcaga aacataacaa attgtaactt
    12061 ctttttctaa ctttatttgt tcatttacac tccagttgta ataaaggtct ataatttttc
    12121 taggattttc agttaatact ggaccatgac ctggacatac agtatctata tctaaatctt
    12181 ttatcttttc tatagcagtt accatagatg gtttaaatgg acccattata caatcataat
    12241 agtatcttaa agcatccaag taatcctttt cttcattttc atcaagtgta tttactatct
    12301 tatcattact atagtgacta ccaaatgaat cacatgttac aagagtttta tcctctttta
    12361 tatatgtgta tatggtatct ggccaatgaa gcataggtac agagaaaaat tctaaagttt
    12421 tgtccccaat tgataatgta tctccatctg taactgcaac atattcaaag tctttgttta
    12481 cgatttcctt aagatattta attgctgttt ctgaagctac tacttttgca tttttagcta
    12541 aatccaaaag cttttcaacg cttcctgcat ggtctggttc agtatgactt acaacaatat
    12601 agtctatttt ttcaaaatct atatttaaat catttaatct ttcaatataa ttgtcaaaat
    12661 gcttatcttt aactgtctca aataaaactg ttttttctgt tccttttaat acatatgaat
    12721 tataagtagt tccataaggt gtatacataa ttatgtcaaa tactcttaaa tcagggtcaa
    12781 gcgaacctac ccaatataaa ttttctttta tttttagtga tttcaatgac ataccgtact
    12841 cctcctaaaa tagttattta gtctctttat accctgcttg ttatatttta aacaaaattt
    12901 attcaaaaaa gaaattattt taaagatagt ttaaatcttc taatcttctt tttctacctt
    12961 caatacagtt ccctttttag aatctacttt tatgtcatat tcatttttat ctttatctat
    13021 tcttatttta taaaaagtaa catctaaatc tttgtctaaa ctccattctt taactattcc
    13081 attttgttct tttaatgcaa tttccatagc ttgttgaggt gtcattatgt catttaaatc
    13141 taatttttct tttctagcaa ctccatttaa atcttctgaa tccaactttt ctgttttatc
    13201 ttctaataca tcttttgtat tagcatcaat tttcatctta tattcattat tatcatctac
    13261 accttccaca gtataaacaa atttatttaa atctctctca agacttaaat ctactatatc
    13321 agcatcctta tatttatctt taaatatgtt tattgcatct gtgtatggca ctttaaaatc
    13381 ttgttccatt aaattttcat tatttttttc atcttttaaa gcgttatttg atgcatttgc
    13441 ctcctttttt gtattatctt gtgcttgtcc tgaatcctta gttggactcc cactacatgc
    13501 agttaataaa cccgctataa gcatacttac cactaataaa tacgtttttt tacacataaa
    13561 aaccctcctt aaatatatta atttattcta tattatgccc tctaaaccct ttatttaccc
    13621 ttttatatta aaaattcctc ctattttatc aattttaaaa ctttatattt actaaaatta
    13681 aagttacata aaaattatac tgtctcaaaa tggaaacaag cctctttttc attgttgaaa
    13741 taataaaaat atattttatt tcgtacaaaa agagtgcctc atgaactaaa aagttcattt
    13801 tgagacactc ccattttttt atatttttac ttacaaaata acagtactta ttaatttttt
    13861 acaaacctta taagtatatc tatatgatat tcttaaattt aaacactata ttaaaaaatt
    13921 aaattttgtt taattctttt accgttaaat ccattttagg atatggaatc gtaattcctt
    13981 cttcgtcaaa cctaacttta acctcttcta gtaaatcaag ataaattgtc caataatctt
    14041 ctgtcttgca ccaaactcta gttgcaaatt taatagcatt atctccatgt tctactactc
    14101 ctataaatgg ttctggttca tttattatta atttatgatt attaacaata tctttaagta
    14161 ctcttctaac atgtagtata tcatcttcat accctacact aaaagtcaaa tcaactcgtc
    14221 tagtattctt tgctgaatag tttattagac tatcatttga tacagaacca ttaggtataa
    14281 gtatctgttt attatctgga gtaaccaatt gtgtataaaa aagacctatt tgttcaaccg
    14341 ttcctccatg acctgctgct tctacgtaat ctcctacttt aaaaggtcta atcaatagta
    14401 taataaatcc tccagcaaaa tttgatagac taccttgtaa agccaaacct attgctaccc
    14461 ctgctgatgc tatcacagca gcaaaactgg acaaactcat tccccaatat tccagaacaa
    14521 tgattataac ggcaacttta agtacactca aaagaagaga ctttaaaaac tttcttaaag
    14581 ttaaatcaat atctctttta ctaagtaata acataacatg gtttacaaat ttttttatta
    14641 ttttaaatcc aatagaaagt ataagtatgc ctattataag ttttactccg cttgtagtag
    14701 cccattctag cagactttcc attatacctc ccatatccat cttattaata tctaaattat
    14761 ttaaatctaa cttgcttata tcatctattt tcgtcgtatc cataaaaaac tccttacctt
    14821 atattttaga accaatatta tagtttaaag ttcttatttt ctatttaata taatacaata
    14881 ccatttgtac atagtaaaca agatttatat tccaattata catattagga aaatgcaaac
    14941 tatttgttat atatatgcaa aatataatac taaattaaac tattaataaa acactatata
    15001 gccttaaaat catcattttt tacccctata tgagatgata ctatagttat aatacttagt
    15061 actataaata ctacaaaacc ttttttatat ccatcaacta tattatatga atttacttgt
    15121 aaagagatag ctataatcaa attaataatt ccacttccta taaattcaaa agtattaata
    15181 acactagttg ccagtccaga ataaatttct ttatttttat acttggcatc attaaaaacc
    15241 tgtagatgtg acataactat acatcccata ataaagaatg atattggtaa aactataatt
    15301 ggtggtttta cctggtatac aactacaatt acaatccata taaacaaatc tatcattgct
    15361 ccaaatttta ttatattaaa tttgctagac cttattttag caaatacaaa atccataatt
    15421 attgaaccaa atataaatcc atatgtaaaa aatgatacta taaacgcaga aaaactctta
    15481 ctcacaccat aaacgtccat tatgtatctt actccccaca agcttataaa tgcacttgta
    15541 agaccaacaa aagagaacat tatcattgaa ttataccatg ttgatttgtt ctttataaca
    15601 gacttaatac catcaacaat attaaccttc tctgactttt catagggttc agtatctaca
    15661 ttgaatccat actcttttgg tgtatctcta acaataatat acataaaaca tccaattaca
    15721 acaccaatta taccgattaa taaaaatgaa tttctccaac caacaagttc agacaaaaac
    15781 acaagtggaa aagtagcaag aactccacct aaatttccta caaatgaaaa tttagctgtt
    15841 gcagaagcaa attctgactt attaaaccat ctcccttgaa tttttaaaat acaaagtaat
    15901 attactgatg ttcctgcccc tacaattaca cgagaaatat atgctaattc tatactttga
    15961 atcaaaccaa ataaaattga ccctaaactt gccattatta ttccaagact gctaattttt
    16021 cttgctccat atttatcaat caaaattcct gcaggtattt gcataaatgc atatgcatat
    16081 aggcaaaagg atgctatatt tgaaatttgt atagaattaa aacctaactc atttgctaaa
    16141 ttgtctgaaa caacagcagt tgacatcctt aaaaataata ctaaaacaaa tgaaaatgta
    16201 attatacccc aaacactcca cttagccttt gtataacttt tcatatcttc tccctcaaat
    16261 ccatatattt ttaaattttc ttgatataac ttatataaag tgtatagtta ttcttacaaa
    16321 tttttacacg caatatcatt atacaacata tgtatatatt taactagaaa taaaacacta
    16381 ttcatattat atacatgaat taactacata aataataaga gccatctttt aacattactc
    16441 aaaagatagc tccatataaa aacatttatt ctaaatttaa ttttttatct aatataaatt
    16501 ttgtagcgaa aaataacgct attgcaacta caagactacc aagtattgca agcataaaac
    16561 taggactctg ataaagatga tataccatat ttgtatcttc atttggtaag atgcttccaa
    16621 ctgcatctcc aacaattgat attactatat ttatagctat aaaagaagca aatgccacta
    16681 tgtttctatg tttattgaat tttggcaatt gtcccattga gattgatgta tataataaca
    16741 aaataaatga tgaatatgaa ataaacatta ctactactaa taataaaata tctaaaaagt
    16801 tttcagaaat ccatttaaaa ctagtgttaa acaaatctaa aatttcaggt agtaaaattc
    16861 cagaagtacc aaaaagcata agaactccaa aagtgaatac tgcaactata aaactaagta
    16921 cagcgtatat aagtgctgtt atacatttag ataatataag tgaactagtg ctaacaggaa
    16981 gagtaaacat taaataacct tcatccccca aaagattttt tctaaacctt tgaattgtaa
    17041 ctacaatagt taaaactcct aatgccataa aaagacttgt taatactagt attcctattc
    17101 cctgtacctg aagtatattt gtattcataa atattccatt aaatacagct actatcaata
    17161 tggctatata taacggtata aatattcttc cacttgcttt taactcatat tttaataatt
    17221 tacctaacat ttaaattcct ccctaaataa tgcatctata gattttcctt tttcttctct
    17281 tattgcttca acgtctcctt gtaacactat ttctcctttt gatatgaata ttatctcatc
    17341 acatatgttt tctatttcac ttattaagtg ggtagcaatc agtaaagtac tatcttcaga
    17401 ataatttttt aatatagtct taagtatata tgaccttgca gctgggtcaa caccacctat
    17461 aggttcatcc aatatatata tgctcgcatt tcttgacatt actaaaataa gttgaacttt
    17521 ttctttagtt cctttagaca ttgtctttag cttttcattt acatcaatat ctaagctttt
    17581 aatcatctca tttgctcttc taacatcaaa atcactataa aaatcataga aaaacttaag
    17641 taaatctgat accttcatcc aatcatttaa ataagttctt tctggtaaat atgaaactat
    17701 ttttttagta tctatggatg gtttcattcc atttatcata atttcaccat tatcaggctg
    17761 taataatcca ttcattagct taatcattgt acttttgcca cttccattag gtcctaacag
    17821 cccgactatt tttccctttg gtatatttaa atcaatattt tttaaaacat tcttagttcc
    17881 ataactcttg tttacacctt taaattcaac tattccatct tgagaaacat tgcttatatt
    17941 tttatccatt ttataattct cctttcagat tttctgtaat aagttttagc atttcatctc
    18001 tatcatatcc aagcttttct aaggttactt ttaatgtatt tatctccaca ttagctattt
    18061 cctctttcat agcttttatt ttttccttat catctgttac aaatcttcct ttagttctct
    18121 gactataaac taaaccttgt ctttcaagtt ctgttagagc cttttgcatt gtatttggat
    18181 taacttccgc atcttctgct agtgctctca ctgtttctaa tttagatcct attttaattt
    18241 cccctgaaat tatttttaac tttaaatgtt ctactaattg tatatatata ggtttgttat
    18301 tatcaagttc ccattccatg ttcatgcctc cttattatat tattgtatta agttgttaat
    18361 acaataatat aataatacaa agtatatgtc aattactttt tagtaaaagt ataaaaaatt
    18421 ttacaaaaaa aatgaacact acattagagt ccatttttaa cacaatttat taaattcttt
    18481 atattacaga ttaattaccc tcttaccaag ttagatacaa ttaaatgttc aaattcttca
    18541 attggcattg gctttccaaa caaatatcct tgtgccatat cacactttac ttcttttaaa
    18601 agtttaaact gttcttctgt ctcaactcct tctgatatga ctttcatacc caactctttt
    18661 gccatttcta ttactttagt aacaattatt ttgcttcttt tactattata agtttccata
    18721 ataaattttt ggtcaagttt taagatatcc ataggaattt cttttaacat atttaatgat
    18781 gagtaccctg aaccaaaatc atccatagat attaaaaatc ctattttttt taaattattc
    18841 attatatcaa ttaaaatatc aaaattatca aatatgatac tctccgttaa ttcaagttct
    18901 atatactttg caggtatatt gtatttatca attatatttt tgtatgtttc tataaaatta
    18961 ttgcaatata aatgtatcct tgaaacatta actgaaacag taactggatt tattcctgca
    19021 tcaatccatt ttctaaggta tatacatact tcttcaagca catataaatc taaatttata
    19081 acaaaaccgt ttctttcaaa aaatgggata aattcatttg gaggtattag ccctttatca
    19141 ggacgtttcc acctaacaag tgcttctgaa ccttgtatct ctcctgtatt aagttctatc
    19201 ttaggttgta agtatataat aaattcttta ttttctagac ttgaaaacat tgtattttcc
    19261 atctcttttt cttttatctc ttggtcatga atcttattat cataaaatgc atatgaactt
    19321 ttatgtcctc cctttgccat tttatgaggt atattagccc tatctatgat tgagttgata
    19381 tctctatctt ctggaagtat aaaatagatt ccacaactta aaactaactt atatttttct
    19441 tcttgattat tattaaacaa gtctaattct tcaaatatag tttttaacct ctttgttata
    19501 tcttcttctt ctatatattt cataattata ataaaattat ccgcagatat tcttgcaaac
    19561 atttcctctt caaatatatt gctcttaata atctttgtta aattacgcaa aatttcattc
    19621 ccaacttcat atccaaataa atcatttata tatttaaatt tatcaatatc tatatataat
    19681 aaagcatact ttacttgagt atttttacat agtattttgt tagcatcaat tacaaattta
    19741 tctatagtat ttgctcctgt aagattatct gtatatgcta tcctttgcaa tttaatttta
    19801 aaatttaatt tatcatatat tatatagaat ataagtatta cacatattat agccataata
    19861 agtattattt gtattgcatg tttgctaata agctgattat tagacacaat agactcaaag
    19921 ttatttatgg agttgttttt atagagtttg cataaagaat agactggtgt tgtgtatgta
    19981 atttgtaaaa ttatacaaat aaataaaaaa aacatcaatt ttttttgtaa attcctcata
    20041 aaaatttcct cccattaaaa cacctctatt ttattagcaa ataagtacat c
//
LOCUS       DAYAKB010000066        20061 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.066, whole genome shotgun sequence.
ACCESSION   DAYAKB010000066 DAYAKB010000000
VERSION     DAYAKB010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.066"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..1334)
                     /locus_tag="ACGI3L_002805"
     CDS             complement(<1..1334)
                     /locus_tag="ACGI3L_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9198502.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELNKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYE"
     gene            complement(1403..2683)
                     /locus_tag="ACGI3L_002806"
     CDS             complement(1403..2683)
                     /locus_tag="ACGI3L_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9198503.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(2810..3070)
                     /gene="hfq"
                     /locus_tag="ACGI3L_002807"
     CDS             complement(2810..3070)
                     /gene="hfq"
                     /locus_tag="ACGI3L_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HFG9198504.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(3184..4119)
                     /gene="miaA"
                     /locus_tag="ACGI3L_002808"
     CDS             complement(3184..4119)
                     /gene="miaA"
                     /locus_tag="ACGI3L_002808"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFG9198505.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINKKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(4157..6124)
                     /gene="mutL"
                     /locus_tag="ACGI3L_002809"
     CDS             complement(4157..6124)
                     /gene="mutL"
                     /locus_tag="ACGI3L_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFG9198506.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(6135..8978)
                     /gene="mutS"
                     /locus_tag="ACGI3L_002810"
     CDS             complement(6135..8978)
                     /gene="mutS"
                     /locus_tag="ACGI3L_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFG9198507.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIENLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALIKQNDDKEKINQVDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(9138..9872)
                     /locus_tag="ACGI3L_002811"
     CDS             complement(9138..9872)
                     /locus_tag="ACGI3L_002811"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198508.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(9841..10854)
                     /locus_tag="ACGI3L_002812"
     CDS             complement(9841..10854)
                     /locus_tag="ACGI3L_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9198509.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(10876..11646)
                     /locus_tag="ACGI3L_002813"
     CDS             complement(10876..11646)
                     /locus_tag="ACGI3L_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198510.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(11621..11911)
                     /locus_tag="ACGI3L_002814"
     CDS             complement(11621..11911)
                     /locus_tag="ACGI3L_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HFG9198511.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(12042..12141)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      12761..12850
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            12903..13079
                     /locus_tag="ACGI3L_002815"
     CDS             12903..13079
                     /locus_tag="ACGI3L_002815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198512.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(13194..13550)
                     /locus_tag="ACGI3L_002816"
     CDS             complement(13194..13550)
                     /locus_tag="ACGI3L_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9198513.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            13927..14307
                     /locus_tag="ACGI3L_002817"
     CDS             13927..14307
                     /locus_tag="ACGI3L_002817"
                     /inference="COORDINATES: protein motif:HMM:TIGR00654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="HFG9198514.1"
                     /translation="MTNADGLSESQMQKIARELNNSETAFIFNNLAKNHQENYDVHIR
                     FFTPTNEVPICGHATIAAHYVRAIENQFNNKTVFQKTGAGILPVDIIKKDNDYEIIMT
                     QGKIEVSPPLQQTYQKRLLNAFGI"
     gene            14367..14765
                     /locus_tag="ACGI3L_002818"
     CDS             14367..14765
                     /locus_tag="ACGI3L_002818"
                     /inference="COORDINATES: protein motif:HMM:TIGR00654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="HFG9198515.1"
                     /translation="MIGIKELSTLNSLSPNLYELSKISQEIKCNGYYIFTLHNKETLQ
                     VHGRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPTPNTEFIFEAVQGEAIKRKGKM
                     LVKVIILDNKPVEVKIIGKAVIAFSTNIEI"
     gene            14996..15607
                     /locus_tag="ACGI3L_002819"
     CDS             14996..15607
                     /locus_tag="ACGI3L_002819"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005777 - peroxisome [Evidence IEA];
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_function: GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HFG9198516.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            15905..16243
                     /locus_tag="ACGI3L_002820"
     CDS             15905..16243
                     /locus_tag="ACGI3L_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HFG9198517.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(16650..18086)
                     /gene="miaB"
                     /locus_tag="ACGI3L_002821"
     CDS             complement(16650..18086)
                     /gene="miaB"
                     /locus_tag="ACGI3L_002821"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HFG9198518.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(18334..19770)
                     /locus_tag="ACGI3L_002822"
     CDS             complement(18334..19770)
                     /locus_tag="ACGI3L_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HFG9198519.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGSMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT         6522 a         3257 c         2167 g         8115 t
ORIGIN      
        1 aattcgtaaa tagaaagagc atatatttga gtagctttta taatatcctc tactattaag
       61 tattcattag cttggtgttc tgtttctggt tttcctggaa aaatagctcc aaatgcaaca
      121 caattatcta aagctcttgc gtatgttgct cctccagatg aaagtggtgt tccatcaaga
      181 ccagtttctt cttcatatac ttttctaagt gtcttaacaa gaagagtatc ttctggaaca
      241 tagattgaat ccaagaaatc atattcttca taatttaaat tgtatttatc tgtcattttc
      301 tttaactctt ttacaaaatc atcctttttg tatgttactg gaatccttac atctattcct
      361 gcaaattctt tttcgttatc aatagttact ctacctatat ttactgttag tttacctgat
      421 acatcatcct tgcagttagg aattatattg tttccattag catcttcacc aataacttct
      481 gctaaaaact taattatatt agaatctata cctatattat taagagctat acaaagtcta
      541 gccactgcat ttataccagt atcacttgct gctgaatgga cactctttcc aattatacag
      601 attttattac cttcaacagt atactcaaaa tttaatttat taagttcttt ttttaattta
      661 tcagagtatt ttccaatata gattgcttta cctggaactg catttaaagc ctttccaact
      721 gacaactcta tatcactttt gctatcacaa gtcaaatgaa cttgtaaaag acctttctct
      781 gcatttgtta ttgggaatct agaatctgga gtaaatccat agtttggtat ttcttcatta
      841 ttttctttat atttatttat acatctccaa agattttctt catcagcccc aaaaatgaat
      901 cttatcctct tattaaagtc tacatttaaa tccataagag ctttcactgc ataaattgct
      961 gatattgtag gtcctttatc atcttgtgtt cctcttccat acaatttacc atcttctaaa
     1021 acagcttcaa atggagggta attccagctt tctaaatcac cttctggaac cacatcaacg
     1081 tgaccaagta tacctatcat tttttcacct tgtcctattt ctgcatatcc ataatatcca
     1141 tctttgtata ctgtcttaaa tcctaaagat ttacataaat ctaatatacc tcttaaagct
     1201 ttatctacat tttcaccaaa tgggcaattt tcagttgctt cagatataac actaggtatt
     1261 tttacacttt cttgtattga agaaatcatt tcatcttgta gagaatttac tttttcttta
     1321 atttgctctt tcatattatc acccttcaat tttcatcata atatactaat aaatattttg
     1381 accttttaaa aaaaaaatat gcttattttt tcagtttttt tataaattca atcgctttta
     1441 aagtccccat ttttgaatgg tcaaatgtaa gtccaccttg gaaataaaca ttataaggag
     1501 gtcttattgg agcatctgca cttaattcta tagaagaacc ttgtataaat gctcctgctg
     1561 ccattatgac ttcactttcg tatccaggca tgtcccaagg aacaggtttt acataagaat
     1621 cgactggtgc agcttcttgt ataccttcac aaaaacttat tacttcatca gcattattaa
     1681 gtctaataca ttgaataata tcacttctta agtcatcata ttttggtaat acatcatatc
     1741 ctaatttttc aaaagctctt gagcaaaaga tagctcccat tacagcctga gatactatat
     1801 aaggcgccaa gaaaaaaccc tgaagtacat ttctagttgt tccaaaagta agaccacatt
     1861 cttttcctat tccaggagaa gtcattctat aagatataag ctcaatcaaa tcttttctac
     1921 cagctatata tccacctgtc aatgcaagcc caccaccagg attttttatt aaagagccag
     1981 ccataacatc tgctccaaca tcagtaggct ctttggtatc taaaaactca ccataacaat
     2041 tatcaaccat tactatagct tctggtttaa cagactttat tacttctata gcttctttta
     2101 tatcactaat tgaaagtgat tttctccaag aatatccttt tgacctttgt atcataacga
     2161 gtttagttct atcatttatt ttgtttttaa ttccttctaa atctaagttt ccatcctcta
     2221 aaaaatctac atcatcatat gtaacaccat actctttcaa tgaacctttt tcttctctta
     2281 tgcctataac tccctctaaa gtatcatatg gtctaccagt aacagataaa atttcatctc
     2341 ctggtctaac tataccttgt atacataaag taagtgcatg tgtaccattt acaattattg
     2401 gtcttacaag agcatcttct gtattaaata ctttagaata aatttcctct attttttcac
     2461 gaccaatatc attatatcca tatcctgtag tccagttaaa gtgcatatca cttagtttag
     2521 attcttgcat agcttttaaa actttatatt gattatattc tcttatttct tttatttctt
     2581 caaacttatc ttttatttct tccattattt cttgcgatag tttaaaagta tcatcatcta
     2641 ttccatagta gtcttttaat aattcttttg tctcattaag cattttatca cctgtctctt
     2701 tattatttta tttaaacatg taaaggagac tattttacta aaacaaataa attatagttt
     2761 ataagttagt ataagtctcc tctcaatcat cttaaattaa attaattatc tatctgttgt
     2821 tattattatt gttgttttgg ttttgatttg ttagattaat atactttcca ggttgtatag
     2881 ttgatacagc atgtttataa atcatgtttt gttgtctatt atccccttct attaatatta
     2941 tataactatc aaaccccttt acaagccctt taacttgcac tccattaact aaatatatag
     3001 taacaggtat cctttctttc cttgcattat ttaaaaacaa atcttgtaaa tttaaaactg
     3061 tatttttcat tagatttgta ccctcccaag attaaattga acttctaaaa tattcctacc
     3121 ttatattcta tataagttat gacaaatttt caatattaag ttgtatactt aaaaatttat
     3181 atattatttt atagaatctt taatatataa gattatttca ttttttaatt cgtctatatt
     3241 ttcatattgg tctaaatcaa accattttgc tgttttatat cttttaaacc atgttatctg
     3301 acgttttgca taccttctag aatctctttt aattatttca atagcttctt cgtatgtata
     3361 ttctccatcc agatacttta atatctcttt ataacctata ccttgcattg atatcatatc
     3421 ttttttaaat cccatactta aaagtttttt tacctcttca accaatccat ttttaagcat
     3481 aatatcaact ctcatattta ttctttgata caaatgttct ctatctctat ttagaactat
     3541 tattattggt tgatattctt cattaaattt taaatcactt gaaaaatcat tcattttctt
     3601 accacttaga caaacttcaa gagctcttat gaccctttta gtattgtttt tatggattct
     3661 attagcagat tcttcatcaa gttcttttaa cttattatgc atgtaatcta ttcccttttc
     3721 agcaagttgt ttttgaagtt cttctcttaa ttcattattg gcatcagatt gtgcaaaatc
     3781 catattatat attaaagagt ttaaataaag tcctgtgcct ccagttacta aaacacattt
     3841 ttccttttta tttatttcat gtatatattt ttttgctctt tgttgaaact ctgaaactga
     3901 aaatggatag tcaggcttaa cttcatctat aaggtaatgc ttcactcctt gcatctcttc
     3961 ctctgtaact tttgcacttc caatatccat atattcatat atttgcatag aatcagctga
     4021 aattatctct gcattcatat cttttgctaa ttttattgac aaatctgttt ttccaacagc
     4081 agttggacct gtaagtatta taagtggtat ttttttcata acattccttt ccatatattt
     4141 taaatatcca aatattttac ataattcttt taaacatttt ttctatttct gtcttagata
     4201 tttcgaccat tataggtctt ccatgaggac atgtaaatgg attctcacac ttttctagct
     4261 gttccaataa actttttatt tcaatatcgt atattttatc atttgctttt atagcagacc
     4321 tacatgccat agatgcaaat ctctctcctt ttaaatcata attacttgta atttcttcta
     4381 tattatcaat tatttgaagt ataaatttct cggtttcagg tactccaaat atagtaggaa
     4441 cacatcttac cattatatga ttattgccaa aaatttctag ctcaaaacca aatttcataa
     4501 ataactccaa gttattttca atttgaagca tatctacatt tgatacttca ataaccactg
     4561 ggtctaaaag tatttgcata tttatatctt gtctatagaa cttctccata tatctttcat
     4621 atagtattct ttcatgtgca gcatgttggt ccaacaaata catagaatcg tctttgctca
     4681 aaattatata agtattaaat acaactccaa ttacagaata tccgtataaa gaaaacttgc
     4741 gttttgaact acacaagtat tcttcttcac tgtccttaat actatctcct aagtaataat
     4801 ttccttcatt tttaattcca tcaacttgaa actcttcttg tatattatca tttgcactat
     4861 cttcacttag ataattaatg ttttttacat catcttctac acttgcattt aggacttcac
     4921 ttactgattg aaattcattt attggttttt cacttgataa agtaacaact tcaatgactt
     4981 catccttacc tttagtaata ttactatttt taggagtaga ttctaataaa tcattatttc
     5041 ttaatttata atctgtactt ttttctctac tgttaatagc gattctaggt tgtgtttttt
     5101 tatcactata agtagcatat tttccaataa gatttgagtg tattaattta acctttaaaa
     5161 aatctctaag ttctatatac acttcttgtt ctttttcaaa tttaatttca agtttattgg
     5221 ggtgtatatt tacatctata catgatgggt ctacttctat atttaagaag cacactgcat
     5281 gtttacctat tggaattata gacttataac tttctgttat tgcatctatg attattttac
     5341 tttttacaaa tcttttattt atatagatat gttgtaagtt tttatttgaa cggtatatat
     5401 tgttattacc tatatatcca ttcattttaa agtgattgca cttaaactct acatctatta
     5461 tattttccgt tatttctttt ccatatatac ttctaatagt gtttacaagc tttccatccc
     5521 ctggagtatt tagcatctgt ttattgttat ttgtatattt aaattgaatg tttggattac
     5581 ctattgcaag tttatttatc aaatcactta tatttatagt ttctgcatga gtagatttta
     5641 aaaatttctg tcttgctggt gtattaaaga aaatatcttt tataatgatg gtagttccat
     5701 tagtagaacc tattggttct ttcgatatta tttttccacc ttcaacatat attttagttc
     5761 ctattatttc atctttagtt ttagttgtca tttctaattt tgatacagct gaaatagatg
     5821 ccaatgcttc tcctctaaaa ccaagagagt ataaatcata caaatcatca atttttttaa
     5881 ttttactagt agcatgtctc aaaaatgatt tttcaacttc acttgaaggt attcctattc
     5941 cattatctgt aatcttaatt agactttttc ctccatcaat tatatctatg gaaattttat
     6001 ttgcacctgc atcaatggag ttttcaataa gttcttttac tacagaagaa ggtctttcta
     6061 caacttcacc tgctgctatc ttatttatag tcaaatcatc taggatgtta attatatttt
     6121 tcatttttac acctctaaga ttttatttct tttgcttttc tttgaagatt ataaagagag
     6181 tttatagcat ctaatggagt catatttaaa atatccagat ttaaaatttc ttctgatagt
     6241 atatctctat ttacactatc aaaagagatt tgagttaagg ctacttcttt tacagaatcc
     6301 acttgattaa ttttctcttt atcatcattt tgctttatta aagcaacttc atcatttaat
     6361 gctttaaatt tagaatttaa tttatcataa tcctttttta tatgtttgta gtcttttact
     6421 ataagttcat gttctatttt tagagattca tatttattct taaaattact ttgatttacc
     6481 ttaactaatt cttcgtccaa attactatta attatattat tgttttcttt atctccattt
     6541 attgcaacac tgttgtaaac atgatttttt tccaagtctt taagtatata ttttgctctt
     6601 tctatgactt cgtctggtaa tttagctaat ttagcaacat atattccata actcttgtct
     6661 gctccctgag gaattatttt tcttaaaaat attattcctt ccccatcttc tttgactgct
     6721 attgaataat ttttaacctc tttaaactct tcttctaaat cagtaagttc atgataatgt
     6781 gttgcaaata atgtcttaca tctaatattt ttttgaatat attccactat tgaccatgct
     6841 aaacttatac catcataggt actagttcca cgacctattt catctaatat aactaaactt
     6901 ctctctgttg cattttttaa tataagggat acttcgttca tctctaccat aaaagtagat
     6961 tgaccttgag ataaatcgtc actagctcca actcttgtaa atattctatc taatattgga
     7021 atatcagcag actctgctgg tacaaatgag cctatatgtg ccataagagc tattatagca
     7081 gtttgtctca tatatgttga tttacctgac atattaggac cagttattat gttaataatg
     7141 ttttctccac gatttaaata agtatcattt ggaacgaaat tttcctctcc tactatattt
     7201 tcgacaacag gatgtctacc atttcttata tcaagtttat tattttcatt tattgctggt
     7261 tttacatagt tatttatatg tgcaactgtt gcaagggaca caaaaacatc tatattagct
     7321 atagtcttag ccactttttg tattctatct atgtttttat atattgtatc tcttatctct
     7381 acaaatatct cgtattctaa agatttaatc ttttcctctg catgtagtat cttttcttct
     7441 atttccttta attctggagt tatatatctt tctgcattac taagtgtttg ctttcttata
     7501 tatgtctcat ctagctttgc ctgtttaaag ttagcttttg ttatttctat ataatatcca
     7561 aaaactttat taaagcctat ttttaatgat ttaactcctg ttttttctct ttccctgttt
     7621 tctatttcct ttacaagaaa ggctccattc ttagaaatct ctcttagttc cttaagttca
     7681 tcactaaaat ctgatttaat tatgtttcca tcttttatgg ttatcgtagg ttcttctaga
     7741 atagcttcat ctattaaatt gtatatatca tctaatttat ccatttctga aacatactct
     7801 tttaggattt ttgcatttga taaatttata gtatctttta aattaggtaa cttttctatc
     7861 gaatttttta agtgaattaa ctcttttggt gttactctct caaatgctat ctttccacat
     7921 attctttcta tatcgtatat atttttaagt atatcattta ggtcttctct taatataaag
     7981 tcatctttta tttcttctat tacatctaat ctattttcaa ttttagattt atttatcaaa
     8041 ggttcttcta catattttct taaaagtcta cctcccattg ctgtagaagt tttatcaagt
     8101 acgtgtaata atgaaccttt tttcttattc cctcttatag tttgagtaag ttctaaatta
     8161 gttctagtaa acatatctag aaccatatat tctgatgaat tgtatatatt tatattatta
     8221 atgttagatg ttatttgttt ttgagtattg tatatataat tcagaagaat tgataagctt
     8281 gactttatta gacctttatc atcaaacttt agtttttgta gataaacatc tggaaaatat
     8341 tcttttaata tatttatatc caaatagtta tcactaaaac tttcatttat gtatatatta
     8401 cttacagtag ctatatctct aagattttct ataaagtcta aatcatttat aattatttca
     8461 gttggatgga tttttgcaat ttcttcaatt accttatctt catttaaaca tgttgcatta
     8521 gtttctcctg tacttatatc aacataagtt agacctatat tagtaccatc cttatacaaa
     8581 gataataaat aattattctt tttattttca agtaaatttc catctaaaac tgtaccagga
     8641 gtgatgactc ttataacctc tcttctaaca attccttttg ctgtagatgg gtcttccatt
     8701 tgttcaccta ttgctacttt atatccattt tcaactaatt ttgatatata tgaattggct
     8761 gagtggaaag gaacaccaca cataggagca cgttcttcta aaccacaagc ttttcctgtc
     8821 aatgctattt caagagcttt tgaagctact aatgcatctt caaaaaacat ttcataaaaa
     8881 tctccaagtc taaaaaacag tatacagtct ttatatctat tttttacttc aagatactgt
     8941 ttcatcatag gagttaattt attcatatct atttgcatta tcaaacctcc ttcttttcta
     9001 attaaatatt atatcatagt agatgattat tattaacaca atatataaaa ttttgacata
     9061 taactaaaaa caatccaaaa tgtatactca cattttggat tgctaagttt aatgcttatt
     9121 aaataaaaat atttttttta caataaagat attatttctt ttttaagttt aatgatattt
     9181 tcaaggttat cttcatttaa ctttctacta tctataacaa attctttctt tactattgat
     9241 ggtttttttg aaataacata aattctgttt gatagcatta tagcttcgtc aatatcatga
     9301 gttataagaa gtattgttga atttactttt ttcttaacat ctaaaagcca tttttgcatg
     9361 gatgttttag ttaatgaatc aagtgcccca aaaggctcat ctaaaagcat tatgtcatta
     9421 gaatttataa aagttctcaa gaagttagct ctctgtctca ttcctccaga aagttctgaa
     9481 ggatatttat cttcatatcc gcttaatcca aacacctcaa aataaggttt taccattgac
     9541 ctagctttac tctttttttc tttttttaaa attagtggta gtgacacatt atctattata
     9601 gttttatatg gcaagagtaa atctttttga tacatataac tatacttacc atttatattc
     9661 actttgccac tatcataatc tgtaagttta gttataatat taaaaatagt actttttcca
     9721 catccacttg gccctaatat agaaacaaac tcaccttcat aaacatcaat acttatatct
     9781 tttaaaactt caatatcttt ataagttttt gatacatttt ctatagatac ttttactttt
     9841 ttattgtggt aaaaattcat ttgtgtaagc atcacttgcc ttcatatcct tatctattaa
     9901 tttatattct tttaagaatg atgtatagtt gttccataca ctatctttca tttctcccca
     9961 tcgtggtgca tcatctttgt acttgcttgc taaatattct tgactcttta aagctagttt
    10021 ttcatctact tcaggtgcat gttttactaa aatttttgct gattcttctg gattttttat
    10081 tgcatattca taaccttttg ttgtagcttt taagaatttt ttagcaagct ctggattatc
    10141 tttaagcaca gtttcattag aaattataag tggtgtataa taatccaatc tctcatctaa
    10201 atcttttact ggtataaagt ttaagtcata tccaattaaa tcagctttaa ctgcatccca
    10261 accttcaaat atccatgcaa aatctacagt tttcatagct gcaaagaaat catcttgacc
    10321 agtattaact atctttaact tattaaaatc agctccattt ttcttcataa ctgctttaaa
    10381 aacagcttct tctgatggag agccccaacc accataagtt tttccttcaa aatctttagc
    10441 tgttgttata ttcttttctt ttggtgatgc aaacccagaa gtattatgtt gtataacagt
    10501 tgctacagct tttattggaa gtggatcttc actagtcttt gcataagtaa cttgttcttg
    10561 atagcttata ccaaagtcag cttttcctgt tgctactaaa gtttctgctc cactttcagg
    10621 tggttgtact atttcaacat ccaaaccttc ttctttatag taacccttat caagtgctac
    10681 aaataatcca gtatgatttg tatttggtgt ccaatcaagc accatagtta cttttttaga
    10741 agaagtatct ttatcattgt ttttgtcttt attgttattt gaagaacatc cagttattgt
    10801 tgccaatgta aaaacactta ctaaacctaa tattcctaac tttttaaaat tcataattgc
    10861 ctccctcaaa tacctttaat ctattaatct atgtcttata acaacttttt ttacagcctg
    10921 tacaattcct acaaacatta aactaaatat aactactaat atagtagatg caaatacttt
    10981 atcaagtgca tatgcacttt ttgacctaag catataaaca ccaagtcctt tcgttccacc
    11041 tagccattct gcaacagttg ctgccattac agcatatgtt gcagatattt taagtccaga
    11101 aaaaaattta tccattgcca taggaaattt aaggtgaatg aatgtattaa ctttatttga
    11161 gtccatagtc ttaaataaat ttaaataatc tttatcaata ttctcaatgc catctacaaa
    11221 acttattaat ataggaaaaa aacaagtaag cattaccatc aatacttttg gcattgttcc
    11281 aaatccaaac catatcataa agagtggtgc tataattatt gtaggtatca tctgtgtaac
    11341 caacataata ggataaagac atttttttat tattgataca aaatccatca atattccaat
    11401 taccaatgat attataattg cgactataaa accaagtatt gcttctccta tagtaaccac
    11461 agcatgcatg gataaatttt gataatcttt aaaaaacaca ttaattatat ctactggtgt
    11521 gggtagtata tactgaggaa cttctaaaac tcctaccata gattgccaaa gaataagtat
    11581 aaacaaaaat gttgctattg gatatatact atctttgact ttatctatga tttctaagtt
    11641 tttcatctat agtcagacct ccagcttttt catctactct agctactgtt atgactcttt
    11701 cacatccaag attaaaaggg attttatgta ccttttttaa taattcaaaa acttcatcaa
    11761 aatcaccttc aacagtagtg ctcattgctc ctatttcaca tttaagacca cttttttcaa
    11821 tttcagcaat acaagcatct actactttat acatctcttc ttcacctttg taaggtctta
    11881 gtggcattac tgctatgtct gcgattacca tttaaatcac tcctttaaaa ataattaata
    11941 cctactaggt atattttgtt ttttattaaa aaattttatt actaaaaaga tattatattt
    12001 aaataaaaga aaagtcttat ccaaaatagg ataagactta tttttatctt aactggtctc
    12061 cctacactgg cattatccaa acaggttcaa agggtcgaga taaaatctcc tctcagcaca
    12121 ttagctcccc gaaatatatt atatcttttc tacttgatta tactacactt atcatatttt
    12181 aacaaatttt ttatttatat tagatatttt atccgttcaa aaatatctaa tataaattgt
    12241 acattattac accaaataaa ttatcttaaa atggtatttt atcaacatct tccaaaacta
    12301 gattaactga attttctagt ttttattttg ctatttcaag catatttgga tgtatatcaa
    12361 ttccatacaa atattgtgct aaatttctgt tttcactcat ctaatttgca atcgttacag
    12421 attacagatt agaaacagtt tttagactct acttatcttt atctacaaaa aatctttcaa
    12481 taaattcatt aataatattc agtaatctaa aaataaacct ctatctggat ttttaagata
    12541 caaacctttt aggaagtatc ttttgtgata atataaaaat tactcgtcat tatcatcaaa
    12601 atcctcagca accaacattt tatataagaa tcaaactcta taatataatt attttatcca
    12661 atttattttt gagaaataaa atattttttt aatttttaaa ttttttaata tgcaccttga
    12721 aaaaagaaac gttttcctat attatggtaa tagtagaata aaactaaata ggcaaaacta
    12781 gagaaattta gtgacgcaaa gctataggga ctaagactta tgaaatgagt tatgtcagcc
    12841 agttgccaaa gagatatttt ctttttgttt ttatgaatgt tttttagggg gatatatgat
    12901 atatgtttat ggataaaatg gatagatgta cacatatact aactgcatat atatgcagtt
    12961 cacgcgatta ctgcaatttt atagatacac aattaaatga ttttatacta gaatatggag
    13021 agaatgtggt agaatcttgt ttgcatcaag tgatggtatt ggtaagcaga tataattaaa
    13081 gaaattttat tttctagaaa acccttttta gttttatcta cgttttataa ttcattaaag
    13141 aactaattaa aataagcttc attatatatt tttcatgaag taaacagtta agtttatctc
    13201 atatactgtt taccccaatt acataattct aataatatag attccaatga tttaccacgt
    13261 ttagtagaca aatattcaac ttttggagga atagtcggat aagaaatcct cttaataagt
    13321 ccatctcttt caagatactt taattcttgt gacagtatct tatgacttat atgaacaact
    13381 tcttttttta attgactgta acgtattggc tcttgtttta aaatatgcca taaaataatt
    13441 gccctccatt tacttcctat cacagtcatg gtaaaaccaa ttgaacaatt aaaatctttt
    13501 tgtctttctt caatatttgg aaattcttca aaattattat ctatatccat ctcaatcctc
    13561 tctttcaaaa tagtaagtat ctaactaaaa agtgcattct tgtttagcgt actaattcgt
    13621 aatataatct tgattaaaaa atagctatgc acactcgtga ctttagtcat gggaggttca
    13681 gtgtagcata gagccttaca taatactact tttttagatg tatatgttta aattttaata
    13741 tagacatatg ttattttatt aattttattt aaacagataa taataaataa taatttatct
    13801 caagttttct atgtagataa actaatctaa tgtttagaaa ggattatata atatgaataa
    13861 aaaatttcgt ctttatcaag ttgactcatt acaaaagaaa aatttacagg taatccagct
    13921 ggtgtaatta caaatgctga tggcttatct gaatcacaaa tgcaaaaaat agcaagagaa
    13981 ttaaataatt cagaaactgc ttttattttc aataacttgg ctaaaaatca tcaagaaaat
    14041 tatgatgtac atatcagatt ttttacacca actaatgagg ttcctatatg tggtcatgct
    14101 actattgctg cccattatgt tagagcaata gaaaaccaat tcaataacaa aacagtattt
    14161 caaaaaactg gtgctggaat attaccagtt gatattataa aaaaagataa tgattatgaa
    14221 ataattatga cacaaggaaa aattgaagta tctccaccat tacaacaaac ctatcaaaaa
    14281 agattactta atgcatttgg tatttaaagg aagatattcg tacagattgt cctattgcca
    14341 tatcatctac aggacattca aaagttatga ttggaataaa ggaattatca acattaaata
    14401 gtttatctcc aaatttatat gaattatcga aaataagtca agaaataaaa tgtaatggat
    14461 attatatttt tacattacat aataaagaaa ctctacaagt tcatggaaga atgtttgctc
    14521 ctgcaattgg tatttcagaa gaccctgtta caggaaatgc taatggaccc ttaggtgcgt
    14581 accttgtaca ttataaagta atacctacac ccaacacaga gtttatattt gaagcagttc
    14641 aaggagaagc aataaaacgc aaaggcaaga tgttagtaaa agtaattatt ttagataata
    14701 agccagttga agtaaaaata attggaaaag ctgtaattgc attctcaaca aacatagaaa
    14761 tctaattata gattccttct aagtaaattt ttgaactttt taatactaat ttaataacaa
    14821 actaatttat atacaatcaa attaattttt ttattatttg ttaatatata tttatcatta
    14881 tattatataa taatatagat agttactata tcttataatt agataaatca taattatata
    14941 ttattgttaa aactcaatta tataattttt aataatatta ttttaggagg taaaaatgat
    15001 aaacgatatt aaaaataaat tcaaaaatta caaaccatat ataaatggat acaagaatat
    15061 gaagagagca tctgttttaa ttccaatagt agaaataaat aacacacact atatattatt
    15121 tgaagttcgc tcaaaaaatt tgaagcatca acctagcgaa atttcttttc caggtggtaa
    15181 aatagaatca ggtgagactc catatgaagc tgttattaga gaaacttgtg aggaacttgg
    15241 aacttttagt gacaatatag aagtaatatc aagtcttgac ctccttataa caccagtaaa
    15301 gtttatcata catccatact taggatatat aaaaaatatt aataatttaa atataaacaa
    15361 ggatgaagtt gaccatactt ttttggttcc tataaaatat cttttagaga atcctccaaa
    15421 tacttatagt aatactgtaa aagtttttcc agatgaaaat ctaccatatg gttcaattcc
    15481 aaaccaaaaa gattataaat ttgaaagtgg aagttatcct attctgtttt ataaatataa
    15541 agattatgta atttggggaa tgacagcaaa aatactagaa aactttttaa attttttatc
    15601 agaataacac tcataataaa ttatcaaaat ttttacataa gaaatttata aaagtttcta
    15661 aatttaacaa ttctaaaata tcaataacta tattttgtag cactttttta ttttattatt
    15721 gtttgaatat ttgatggttt tcaatgcaat ttcaacataa atactatata ttagtgtata
    15781 ctgttgatga attaaagtat gataatctat ttaataaagt atgaagtaaa tgattttaat
    15841 gtgcctttat ggtaaaatta ctaataagta ataaaattaa ttaaaatata tggaggtcct
    15901 tataatgttt gctgtaggat ttgttgttat aattgcactt gcctttttca ttttaagtgt
    15961 actattattt aatggaaaag ccagtatgct actagcaggt tataactcta tgagtaagaa
    16021 agaaaaagca cgatacgata aaaaaaaatt atgtagaagt tctagcattg ttacttttat
    16081 tgtctctata atgctattta ttatggcgtt tttgggatat agaatagaga gtggtcaaat
    16141 ggacgaaaaa aaaatggttc ccttttctat aatatttata atagtcatac tttccagtgt
    16201 attttttaat atcctctact ctaacaaaaa atgtaaaaaa taaatagttg taagttgagc
    16261 agttaattat aaaagattga ctgctttttc atgtatattg actactctta ttaaatattt
    16321 taacatttaa aaatctatgt aaaaataatg aatatagtac aaacttctaa taatgatttt
    16381 acctttgtgg ttacagtcca ctatatataa tttaatatga taacagggaa ttattaatga
    16441 caactaagta aacttttata aaatataata aaacaaaaat agatgtacaa tgaaattata
    16501 tcttatatca aatttatttt tattaatagc aaaaacttac attagcataa catatgacaa
    16561 attcgcttaa aataaaaatt tttaatataa tttgttctat agtacatcta ttttgattag
    16621 tttacataat tttattattt tgtacaatat taattattta ctaatatccc atttaatgaa
    16681 aaagttctag gttcagtaat tttgaccata actaatttac caattaaatc atcatttcca
    16741 ccttcgaaat ttacgagttt attttgtcta gttctaccag caaacttatt ttcattattt
    16801 ttacttcttc cttcaactag aacttcaact attctatctt tatatccatc atttatttct
    16861 gcagaaatcc tatttacagc ttctaacacc ctattaaatc tatcatgctt tatatcttct
    16921 ggtatttgat tttccatttt agcagcagga gttccctgtc ttttagaata aataaatgta
    16981 aaagctgaat catatctaac tttttcaacc acatctaaag tgtccaataa atcttcttct
    17041 gtttctcctg ggaaaccaat cattaagtct gtagaaaaag caatacctgg aacttccttt
    17101 ttagcttttt ctattatttc taaataatat tcctttgtat aatgtctatt catttttttc
    17161 aaaaggctac tgcttccgca ttgtattggt agatgtaaaa actcacacac cttatcacaa
    17221 tctctaattg cgtatattac ttcatcagat atatcttttg gatgagatgt cataaatcga
    17281 accctttcaa ttccttctat atcattcact tttcttaaaa gttctgagaa tgaaactgga
    17341 ttttcaagtg tcttaccata agaatctaca ttttgtccaa gtaaagtgat ttctttcgtt
    17401 ccatttgcaa caagctcttt tatctcgtta attatatctt caggagttct acttctttct
    17461 cttcctcttg tgtatgggac tatacaatat gtgcagaaat tattgcatcc atacattata
    17521 tttacaaatg cttttaattc aaattttcta ttacttctaa gaccttctat tacttctcca
    17581 tccacatccc atacatccac taacattttg tcagaattta ttgattctgt aagtaattgc
    17641 ggaaatttat atagattatg tgttccaaat ataaggtcta catgtttata tttttttctt
    17701 aattcctcta caacatgtgg ttgttgcatc atacatccac atacagctat tttcatatct
    17761 ggattttttc cttttagatg ttttaattgt cctaagttac catatacttt tagctctgca
    17821 ttttctctaa ctgcacaggt gttatatatt attaaatcac tttcttcaac catcattgac
    17881 atttggtatc ccatctcttc taacattgaa cataattttt ctgaatcatg ttcattcatt
    17941 tgacacccaa aggtttgagt aaacacgagt tttctctttc cagttctgtt gaagtattct
    18001 tcattttgtc tgtgtatttg ttctatatat ttatcttgtt cttgtatttt ctctataggt
    18061 attgttactt gttttctttt gctcacgtct attcctccta gttaatttct tatattacac
    18121 ataaccttaa ttatatcaaa taagaaaaat cttttaaaga tattattatt tttctagttg
    18181 tgttttaata gtaaatctaa tgatttatat atactatatt tctaaaatat aaaatcatat
    18241 aattattata ataataaaaa gatgttttaa attaaaactt aaaacacctt tccttaaata
    18301 aaatatatga tttactatta aatacaatta catctattca ttttcaatta aataacaatc
    18361 atttaatatt aaatattgac cttcctcaac cgttatatat cttcttcctg aaaaagtatc
    18421 attagtaact attccctctg cattacctaa gctatcattt ctaacttcat aatatgcatc
    18481 agaagaattt gacattataa tatattctcc agcaggaatt tctaatccaa ttttatacat
    18541 accatttcca aacttaccat tcttggcctt ctgggcttta gcatactttg ctaatgtcat
    18601 tgttgaatcc tcaattttaa tatattgacc attctttaag gtgatatatc tagtcccact
    18661 aaaaatatca tttgaaagta tactatcagc attacctgta ctatcacttg taacttcata
    18721 ataagaagca taacttcctg agtttgaagt tattaagtat tcacctgctg agatatcttt
    18781 tccaacctta tacattccat cttttatagt ctttgtagta ggtttaacat tttttacaac
    18841 cccagtatta atatctccaa ttccatttgt tatatttaaa cactgttgta ctatatttga
    18901 atctatatat cctatagaag ttatcttctt agcatttttt aaaatgcttt tattgctacc
    18961 atcattaact aaaaccattg aaccatgttt tgataaagaa gatcctacaa gtgcatttgt
    19021 taattcataa gctccagcta tataaaactc tctagcatcc ttataaaact tatttattat
    19081 tgctttatta gtttcaaaac gagtactccc ccctagtcta gtagatttag tattgtttac
    19141 taaagtggta ctcattgaag ctgttcctcc tattacataa gactttaaac cactagttga
    19201 aaaaggtata ctttgtccat tagtaagaat tattggtgct ttatctcttg ctgctacaga
    19261 tgcaatactt atagcatctg cttctccttt atatgcattg gttagcataa cagtattgac
    19321 tttttttatt gaatttattt cttttgcaac attataactt gtttttattc tgtcatttcc
    19381 cttaattctt acaactttca ttttcttaga ttttaatgaa ttttcgacag atgtactaat
    19441 agaatatgtt cctccaatta tataaacttt tgatacattt tttaatcttg cagatgtctc
    19501 agttggtata gtattttttt cagttaatag tataggggca tttaaagctc ctgctagtcc
    19561 acttgcactt aatccatctg caatagagtt actagtatta attaatatag cagttttata
    19621 tgcattttta tctgctattt tacctgcgat ttcatactta ttttttcctt gtattttttc
    19681 tacagatgat attgcatcta ctaattgaat atttgcaaat acaaaagaaa tacttaaagt
    19741 caatgttaat attcttttat agaatttcat aataaaattg tccccctcat aataaatttt
    19801 taatatataa atacatattc ttaaattagt tatgtactta acaaacttat gtaaaattgc
    19861 aaattatatt aagcatatta caaataaata ttaatacaat tattcattta gctataattg
    19921 tatttacatt tatattaaaa atcaactaga tttgtataaa tacttataat tatattttta
    19981 ttcttaatat tttttttatt atgttatttt aatagattta tttttctttt ttaagcatag
    20041 agatgtattt ttccatatat t
//
LOCUS       DAYAKB010000067        19654 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.067, whole genome shotgun sequence.
ACCESSION   DAYAKB010000067 DAYAKB010000000
VERSION     DAYAKB010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.067"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..843)
                     /locus_tag="ACGI3L_002823"
     CDS             complement(<1..843)
                     /locus_tag="ACGI3L_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HFG9198520.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVN"
     gene            complement(1209..2603)
                     /gene="gltA"
                     /locus_tag="ACGI3L_002824"
     CDS             complement(1209..2603)
                     /gene="gltA"
                     /locus_tag="ACGI3L_002824"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HFG9198521.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            complement(2603..3496)
                     /locus_tag="ACGI3L_002825"
     CDS             complement(2603..3496)
                     /locus_tag="ACGI3L_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HFG9198522.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            4122..4973
                     /locus_tag="ACGI3L_002826"
     CDS             4122..4973
                     /locus_tag="ACGI3L_002826"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HFG9198523.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(5106..6719)
                     /gene="ggt"
                     /locus_tag="ACGI3L_002827"
     CDS             complement(5106..6719)
                     /gene="ggt"
                     /locus_tag="ACGI3L_002827"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HFG9198524.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(6944..8881)
                     /locus_tag="ACGI3L_002828"
     CDS             complement(6944..8881)
                     /locus_tag="ACGI3L_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198525.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEVEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVAKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(8868..9635)
                     /locus_tag="ACGI3L_002829"
     CDS             complement(8868..9635)
                     /locus_tag="ACGI3L_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198526.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            9923..10597
                     /locus_tag="ACGI3L_002830"
     CDS             9923..10597
                     /locus_tag="ACGI3L_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9198527.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            10621..11625
                     /locus_tag="ACGI3L_002831"
     CDS             10621..11625
                     /locus_tag="ACGI3L_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFG9198528.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            11737..12966
                     /locus_tag="ACGI3L_002832"
     CDS             11737..12966
                     /locus_tag="ACGI3L_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFG9198529.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALSSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            12974..13648
                     /locus_tag="ACGI3L_002833"
     CDS             12974..13648
                     /locus_tag="ACGI3L_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198530.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            13651..14883
                     /locus_tag="ACGI3L_002834"
     CDS             13651..14883
                     /locus_tag="ACGI3L_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198531.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(15169..16434)
                     /locus_tag="ACGI3L_002835"
     CDS             complement(15169..16434)
                     /locus_tag="ACGI3L_002835"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFG9198532.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(16487..17635)
                     /locus_tag="ACGI3L_002836"
     CDS             complement(16487..17635)
                     /locus_tag="ACGI3L_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HFG9198533.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(17726..18271)
                     /locus_tag="ACGI3L_002837"
     CDS             complement(17726..18271)
                     /locus_tag="ACGI3L_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HFG9198534.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(18494..19438)
                     /locus_tag="ACGI3L_002838"
     CDS             complement(18494..19438)
                     /locus_tag="ACGI3L_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9198535.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT         6735 a         3191 c         2352 g         7376 t
ORIGIN      
        1 attaactatt agatttttaa agttcttaaa tatattacat tttgatacta aagtccaatt
       61 agtccacttt atgttcgtat attttacatt atataatctc caattatccc aagataaaaa
      121 atcaccttga cattttttat ttatattttt taagatttca cttttagtgg ttcctataat
      181 attcccttct aaatcaagca tcttactttt atcatttaca tattttttgt ttggatgaga
      241 aataatagta taatctttat ctatcattag aaatttaata gaatcatcaa aattgcttct
      301 acttattaaa ttatttacat cttgaaaata aaaagaagca aaaatggtcc caatcatctc
      361 attatttttt acaattggta catatatgat aaatactttg tcacctgtta cattactgac
      421 ttcaatatct gaaactacta cttgctttgt tttaattgct ttctcaaaac taggcttatc
      481 ttttattgag ttaacatttt ccctatatgt acttgaagca tttccttttg tatctgttat
      541 accaatcata aaaagattat attccttttg atatggactt aataattttc ccttttcaat
      601 tagtgatgtt tcaccattag aaaatctatc atcttgacta agagctttta ataaagatat
      661 gtttacttct aaatagtttt caagttctct ttttgatgcc tcaatcatat ttctagaagt
      721 aatttccata gagttacttg catatatgat ggtacttgtt aaatcaatca aaactaatag
      781 tattaataag attaatatat gcttaaaaac tagcccatca aatacttttt ctcttttttt
      841 catattaaaa taccattaat tacacaattt atttttctat tatttaatgt tagatttgac
      901 aaatctgatt ttattagcca cacattattc actccttaca agacctttat tgtataacta
      961 ttttatcata gttagacaaa gttatgttac ttagtatcaa atattacaat aataactgat
     1021 aaattattaa accatctaaa aaagtggcta catcaaaata gagattgtac taagacctaa
     1081 aagttagact ttctacagga atgaaatttt cattgttgaa atgattaaaa catatttgat
     1141 tttgtacaaa aagagtgcct catgaactaa aaagttcatt ttgagacacc ctctctttaa
     1201 tttacaaatt aagcattaac ttttgctttt aaatattcat ctattgatgc tgctgctgtt
     1261 ttaccagcac ccattgcaga tattactgtt gctgctccag taacagcatc tccacctgca
     1321 aatacaccct ctttagaagt ctgaccattt tcatctgtta ttaagcatct cttcttattt
     1381 atatcaagac tctttgttgt agaagatatt agtggatttg ggcttgttcc aagtgacatt
     1441 ataactgtgt ctacatcaag tacaaattca gaaccttcta tttctatagg tcttcttctt
     1501 ccagaatcat ctggctctcc taattccatt cttatacaaa ccataccttt aacatatcca
     1561 ttttcatcta ctaaaatttc cttaggattt gttaatgtat taaatataat gccttcttct
     1621 tttgcatgat gaacttcttc agctcttgct ggaagctctt tttcacttct tctataaact
     1681 atatatgatt ctgaacctaa tcttaatgca gttctagcag cgtccatagc aacatttcca
     1741 ccacctacta cagcaacttt tttaccagaa ctaataggtg tatcataatc atctctataa
     1801 gccttcatta agtttactct agttaaaaac tcatttgcag aaaatactcc atttgcattt
     1861 tcccctggta tattcataaa cattggaaga ccagctcctg aacctatgaa tatagcttca
     1921 aatccttcat cttctataag ttcatctact gtaattgttt taccaacaat tacattagtt
     1981 tctattttta cacctaattt tcttatattg tctatttcag gttgaacaac agcttgtttt
     2041 ggaagtctaa actcaggtat tccgtaagtt aaaactccac ctggctcatg cattgcttca
     2101 aagattgtta catcatagcc ttttttagct aaatcaccag cacaagctag acccgctgga
     2161 ccacttccta ttactgctac tttttgattt ttcttaggct ctgtatcaga taaatttatg
     2221 tcattttctt ttgaccaatc tgctacaaat ctttctaatt tacctattga tacagcatct
     2281 gattttattc caagtataca tacaccttca cattgacttt cttgtgggca tactctacca
     2341 caaacagctg gtaatgaact gctcttagct attactttag cagcaccttc tatatcatct
     2401 tctttaattt ttgttataaa ccctggtatg tcgattccta ctggacatcc acccacacat
     2461 tttggttttt tacaagctaa acatctatta gcttctgcca tagcttcttc tttattatac
     2521 cctaagcata cttcatcaaa atttgttgct ctcacagcag gttcttgttc tctaactggt
     2581 acttttactt ttttagcatc cattatttgt tacctccaca tccacaatta ctatgatgat
     2641 gactatcgcc ttcttcaagt tttagcatag ctcttccctc ttgagtcttg tacatagact
     2701 gtcttctcat tgcttgatca aaatcaacta aatgaccatc aaattcagga ccatctacac
     2761 atgcaaactt agtttcattt ccaacactaa ctctacaacc accacacata cctgttccat
     2821 ctatcattat tgtatttaaa cttactatag taggtatatt tagttcttta gttaattggc
     2881 acataaattt catcattatc attggtccaa ttactattgc ttggtcgtat tttttacctt
     2941 gattatcaac taaatctttt aataggtctg taactcttcc attaaatcca tatgtaccat
     3001 catctgttga tacatataca tttttagcta cttttttcat atcatcttct aatataatta
     3061 attctttagt tcttgcacca attattacat ctacatctaa tccatgctct ttaaaccatt
     3121 taacttgtgg ataaactgga gcagaaccaa ctccaccagc tacaaataat atctttttat
     3181 ttcttaattc ttctatatct tcatgtataa attcacttgc ttgtcctaat ggccctacaa
     3241 aatccattac aaaatcgttt tcttcaaaca ttgctaactt tttagttgaa gcaccaactg
     3301 tttggaatac aatagttact gttccttttt ctctatcata gtcagctatt gtaagaggaa
     3361 tcctctctcc tttttcatca tttttaatta ttataaattg acctggttga gaagattttg
     3421 caactctagg tgcctctatt tccattaaat aaatactatc tgttaattgt ctcttactaa
     3481 ctattttatt actcatctcg ctattctcca ttctaacaaa tatatttttc ccactttaaa
     3541 tttaattaaa aacataaaca cacaaaacta taactcttta taatataata ttagttcttg
     3601 gttgattgtt ttgtattgga catcccccct ataataatta taactgccca aactacaaat
     3661 agttgatatt aacaaatttc ttgtaaatgc caataaacac taagtctata tcatacgtct
     3721 aatttgttat agatttaacc taatacacac ttaaagtata ctatattatg ccaaatttgt
     3781 aacaaaaatt ttataaatac ataataaaat ttttttattc aattatttat ttaataaatt
     3841 aacttaggtt ttcataataa cactaatttc tttaaaaact aaacgtgtat aaggctttaa
     3901 tctattgcaa taccagcttt catattgtat aaaatatact cttattttat tatatatcta
     3961 aaattttcaa tattcattaa ttatttgaat ttttatataa aatttttaca atttctaaag
     4021 atttatttac ttatgtaata aattataata atattagttt ataaagttaa taattaatat
     4081 aaattaaaat aaagataata taaacacagg aggtacattc tttgaaaaac attatttcag
     4141 caaaagaact tatatcaaaa ctagaaaaaa atgataatct agttgtaata gattgtagat
     4201 ttgatcttat caatagaact tatggtattg attcttataa aaaaggacac atcaaaggca
     4261 gttttatctt agatatagac aaggatttat catctcctac aaaagaacat ggtggtaaaa
     4321 atcctttaca agacccttta atactaaaag aaaaattaga aaaaatgggt gttgataatg
     4381 acactacgat tgtaacttat gatgatggag atttaaatgg agcttgcaga ttatttttcc
     4441 aattaaaaca tttggggctt aaaaatgtct atgtactaga tgggggaata acatctttcg
     4501 taaaggaagg tggagaattg gaagagaaag tgaatatacc aagttgtaca ggtaaggaaa
     4561 ttagaccaaa tataaacaat gatttagttg ttccaatgga atatgttaaa tctaaattat
     4621 acaaaaaaga tactgtaata atagattgcc gtgctaatga gagataccag ggtttagttg
     4681 aacctgctta ctcaaaagct ggtcatatac caagtgcaaa aaattatttt tgtaaggatt
     4741 taataaaaag tgactttgaa aatggctcac ttaaagatat agaattttta aaaaaattct
     4801 ttaaagattt aaataattat gatgaagtaa ttttatcttg tggttcaggg atatctgctt
     4861 gtgttaacag tcttgctctt agagaactgg atatacctca caagatttat attggtagct
     4921 ttagtgactg gattagttat gatgacaatg aaatcaaaac tggtcaagaa taaggctcat
     4981 aatctatata aaatcagcat atgatagctt aaattttgta aaggcgtcag tcattgtaga
     5041 ctttcgcctt tacttattat ttcatatact ctttaaattt attatatata ttttagttga
     5101 taatattaat aaactgcaat atgaccatca catcttgatt ccgtcccaca aatataactt
     5161 tcctgttctg ttttaaatat tatttgacct cgtcccatgt cgacagtatc atgaattact
     5221 tttatttcat gacccttttc aattaatgaa tctattatat gctttggcat ctctggttca
     5281 acttctattt cttttccttt tatccactgc catcttggag catctagcgc ctcttgtgga
     5341 tttaatccaa aatcaatcat atttgttaac acttgaatat gtccttgtgg ttgcataaaa
     5401 gctcccatta caccaaatgg acctattgct ttatcttctt tacctaaaaa tccaggtatt
     5461 atagtatgat aaggtttttt aaatggtttt actacattgt ggtgtttagg gtctaaatta
     5521 aaattatttc ctctactatg taaagcaatc ccagttcttg gtatcacaat tcctgaacca
     5581 aaatttatgt aattgctctg tatatatgaa accatatttc catccttatc tgcagtacaa
     5641 aggtatactg taccaccaca atatggctct cctgcagttg gatacaaagc ctctttattg
     5701 tcaatcaata aacttctttt tttagcatac tcttggctta gtaattcctg aatctttacc
     5761 ttcatatgct ctatatcagt tacatatgtt ttagaatctg caaaagctaa ttttaaactc
     5821 tctataattt tatgtatgtc ttctacattt tctatatttc cttctaattc caattctttt
     5881 aatatgttaa gtgccattaa aactgttatt ccatgaccat ttggtgggat ttcaaatatt
     5941 ttatatccct tatattctgt acttataggt tctacccatg ttggataaaa acactctaag
     6001 tcactctttc ttatagcccc attaaatttt ttagaatatt catctatttt atcagcaagt
     6061 cttcctctat aaaagctttc agcctgagta tttgctatct cttctaatgt acttgcctgt
     6121 tcttcacata taaatatatc tccagcctct ggagctttac catctttaga aaatgtatca
     6181 aaccatggtt tgaactcttc tccaataagt tctttttcat agagttcata tgattttttc
     6241 cataccttag ctacattagg agatactacg tatccctctc ttgcatagtt tatcgctgga
     6301 gataagcatt ccattaagct aagtttacca tattttttat ttaattctga ccaagctgct
     6361 ggtattccag gtacagttac tgctccaaac ccatattttg gcatttcttt catattatta
     6421 taatttttta attccatatt ttctggagca aagccactag aatttaaacc atacaatcgt
     6481 ttttcttcct ctatccaaac aagggcatat gcgtctcctc caatcccatt gcttgtaggt
     6541 tctactactg ctaatgtggc ggctgttgca actgctgcat caacagcatt tccacccttt
     6601 tttagtattt caagtccagc ttgagatgct aatggtgttg atgttgcaac tgctccattt
     6661 ttagcataca cgacatttct tattgatgag tatttatgtt ggtaggcatt aaacttcata
     6721 aatttcagct cctcgtcatt ttttatttga tattctgctt agatttatta tataacatca
     6781 agtaatgtaa ctgatacaaa atgatataaa atatagactt tttcctaact ttaattttgt
     6841 ctttaaataa atatcttaaa ctcaattcta gtattttcta tctgcactta aataagttat
     6901 tttattcaaa acatatatct aattcttttg acttaaaaat aatttattct tttatcatgt
     6961 ttagagcata ttttaaagtt aaaaaataat atataaaata tcctataaaa taaatgacta
     7021 gagttatgat aattggtaca agtaatgacc ttggtataaa cttttgtgct atagacatag
     7081 caaataaatt atgaactgta cctacaacta atggcattaa aaatataact tttaactgtt
     7141 ttgatattat tttctcaata tctttattat ttgctccaag ttttattaac ataatatatc
     7201 tttccttatc atcatatata tttgataatt gtttaaataa gattatacta cctgtacata
     7261 aaagaaatac tacagacaaa aatatgccta taaacagcat tagaccactt aattttatca
     7321 agttattata actttcaata cttgatgtaa aattaaaagg ataagtaaat ttcatatttt
     7381 cacttactat attttttaat tttaaagtca aatccagttc ttttttttca ttttttatat
     7441 caattaatct tattaatcta gaatttccat gtaattttaa ctgattaaat acgtcatctt
     7501 ttgctacaat taaatcaaac gtagcttgtg aatttatttc tggctccaag atgctttttt
     7561 gtactttaaa cagatttata tcatactcat ttgtatcttt aatatgcaag tttatttttt
     7621 caacctcaaa gtctttaaaa aatatttttt tgtatgaatc agaaacatag tacacagatt
     7681 cctttgaagt taattcttca taattgttat tctgatattg tcttaatttt ttaaaatcac
     7741 tttctctaat aatatctaca gacgttctat cttctatata actatttcca tttttataat
     7801 acatttcaat atttatatct ttgtctataa gttctattgt tttatcaaag attatcttat
     7861 tatctttttt atatttatat aataatttgt caatttcgtt atttacataa gaatttccta
     7921 aatttatggt ataactgtat ttataatttt cacttatgtt cctatctata tcgtaataaa
     7981 gtgatatggt aaaccctagc atagttacac ttgtagctat taatattgct attacagcca
     8041 atacactact attgctcttt aatttaaatc caagttcaga aaatgcaatt aaattctgtc
     8101 ccttataata aaaacttttt ctcttcttaa cagcatcaat aatcatatac atcgttgatg
     8161 aaaaaaataa aaaagttcca ggtattattg taactaatat aaaaactgaa agcataatat
     8221 tttcagcaat aaaataacta attgacatta aataagaaat agctattaat aaaacaccaa
     8281 gtacacattt taactttata aattttttaa acttatactt ttctggatat ttattaaata
     8341 actctataat tctcttattt ctgataacta tagtatttct tattccaata actatgaata
     8401 ttattaaaaa taccgctagt gtctgaacta aggcctttat acttaagttc atatttacta
     8461 ctatcatttc attcattaat tttacaagca tcatagtcat aagctttgaa aataacagtc
     8521 ctaaaaatat acctattagt attgcaacta tacccatcaa aaaagtttca tataaaaata
     8581 tttttcctat ctgatttttc ctcattccaa gtaaactata agttcctact tctcgcctac
     8641 gtctattgaa aaaaaatgag tttgaataat atataaataa aaatacaaat accactatta
     8701 caattgaact tgtattaata ctcatcctag ttttctctcc aagtgaactc aacgcttcat
     8761 tatactctat agatttaaaa ctaaaaaata caaatacact aaatacaatt gaaataaagt
     8821 acattaaata attaaaaaaa ctattcttta cattttgcat tgcaattcta aataaagtca
     8881 tttttattaa ctcctccaat taaggaaact gtatttacta ttttattata gaactctctg
     8941 ttactttctc cctttacaat ttctgtgaat attattccat cctttataaa gagtattcta
     9001 ttgcaaaaac tcgcacttat agcatcatga gttaccatca atattgtttt attgctgtct
     9061 ttgtttaatt ttaatagaca attcaacaaa tccctagcag atttagaatc taatgctcct
     9121 gtaggctcat ctgcaagtac taatgatggt tttgttgcta tagctctaca tacagctcct
     9181 ctttgctttt gtccaccaga aacttcgcca gggtatttat ctaatataga ttctatattt
     9241 aattcttttg aaatctcttt tattctattt tctattactg atactctttc attttttaaa
     9301 gaaagaggca acattatatt ttcttttatt gtaagtgtat ccaaaagatt agaatcttga
     9361 aatacaaagc ctagattatc acgtctaaaa tctgccaatt cattttgctt cattttaata
     9421 gtattctttc catttatata aatatctcct gatgaaggta aatctattgt agaaataata
     9481 tttaaaagtg ttgatttacc agcaccggaa gaccccataa taccaacaaa ttctccttta
     9541 taaaccttga aagttattcc tcttagagct tcatgttttg aaccttttct tccatactcc
     9601 ttttttatat tttcaacaga taatatttct tccatagtta ataatcacct ttcatcacaa
     9661 ttagttattt atcaattctc acaaatatat tatatatatt aaaatggctt ttaaacattt
     9721 aattatatta atttaaggtt acattttcgt aagtattaat tatatttctt caaatttatt
     9781 gcaattatgt ttaaaatata atttatcaag taaaatatag ttatattaat ataattattt
     9841 taggtaataa ggtagaaata ttttaattta tcaagtagaa tatagttatg ttaatataac
     9901 tattttgaat taggaggtaa gaatgtttaa aataatggta gttgaagatg acgtctcatt
     9961 gaaaaatatc atagcaaagt gtcttactaa atggggacat gatgttcatc aaatagaaaa
    10021 tcttgaaaat ataatagaag agttcaaaaa ctataaccca gaattagttt tattggacat
    10081 aaaccttcca ttttatgatg gttttcattg gtgtaatgaa ataagaaaaa tttcaaaagt
    10141 tcctataatt tttatttctt caagaaattc taatatggat gtaataatgg gtgtaaattt
    10201 aggtgcagat gattatatac aaaaaccttt ttctgtagat gtcttagtag ctaaagttaa
    10261 tgccctttta agaagaactt ataattttgt tgataataac tcaaatcaga ttattcacaa
    10321 tggtgttact ttagatttat caactgcaac aataaactat gaagataata ctattgagct
    10381 aacaaaaaat gaaatcaaaa ttcttcatga gcttatgaaa tataaggggc agatagtaag
    10441 taggaataaa ctcatgaaaa aattatggga taatgattgg tttgtagatg ataatacatt
    10501 aactgtcaat gtaaatagaa tacgctcaaa gttaaatgaa attggtttag aagattttat
    10561 agaaacaaaa agaggattgg gttatataat cagttaaaac aattctaagt aggtgaattt
    10621 atgagcttta aagattttct caaggataaa ctaggttttt tagtatacaa ttttactttc
    10681 ttaattttta cagtatcagt tattatattt tctcctgtag atgtttttct gactgatact
    10741 attttatata tattagttgt aaatgttgtg tttttatttt tatatctatt tattagctac
    10801 atcaagaaga acaaattttt agataagata aaaaatgata cattcaaaat taatatgaat
    10861 gatatagaat tagctagatg taaaaatgaa gaaaaaatat acttgaacat tattaaaaat
    10921 catcaatatc aatgtaataa cataataaat aataatatcg agaaatttga agaaaacaaa
    10981 gagattttaa atatgtgggt acatgatgta aagataccta tagctataat aaaactcatt
    11041 cttgaacaaa atgaaaattt aattgatgaa aaaatttcag atgacataga tagtgaaata
    11101 tttagaattg aaaactccgt tgaaaaaatt ttatatttat caagactcga agattttcat
    11161 aaggattttt taattcaaga ggtaaatatt gaaaaaatca ttagaaatat tataaaaaaa
    11221 tactcaaaat attttatttc aaaaaaaatt attttagact taaataattt gaattttaag
    11281 gttttatctg atgaaaaatg gctatacttc atattcgagc aattattgag taattcccta
    11341 aaatactcct cattaggaga taatatatct atctattgca aaagaaccaa aaattattta
    11401 caattaagag tggaagatac tggttgtggt ataaaaaagg aagatttaaa tcgaatattc
    11461 aataagggat ttacaggtaa taatggaaga aacaattcta aatctacagg tcttgggctt
    11521 tatttagtaa aagaactttg tgataagctt ggtcataaaa ttgatgtaga ttcagagtac
    11581 aaccaatata caaaatttac tattacattc aaatgtgatt tatagtatct tattattgat
    11641 agtttatttt cattaactta tattcaactt cttatagtaa ttctatatgt acatcccagt
    11701 atataattaa gtagttttta taaaaaggag gaagacatgt cttttctaaa aaaatttaaa
    11761 aataaaagat ttagaaataa cagttttaaa agtaacaact ttagaaatag cagttttgga
    11821 agtagtggct tcaagtctaa aaataaaggt tttaaaaaca atccctttaa aaataagaga
    11881 ttcaaaatat atgcaggaat agcagtaatc atacttttaa ttctaggagt tcttgcttat
    11941 gttgattcga aaaacactga attacaagct aatgaaaatt ttatcgaaac atatactatt
    12001 cctgaaaatg aaaaaatatt tataaatggg atggttgttc ctaagcaaac taaggacttc
    12061 aatatatctg gagattatga gttaagtgat gttaatgtta caaatggtca aaaagtaaat
    12121 caaggagacc ttctttttac tgctaaaaat ccaactataa tagcagaaat agatagttta
    12181 aaatcacaac ttagtcaata caaaaaacaa aaaatatcac tttctgatat tgctgaaaat
    12241 aaagatgcta ttgcttctat aaatgcacag ataactgctt taagctccca gatagcttct
    12301 ctggataaaa aagcttatga cagagttact gctccttttg atggcacagt atacttgaat
    12361 gaccaaactg gaaatccaga ccaaccagtt tcatttatga ctattcaagg tctagagttt
    12421 tatatgaaag gacaagcaag tgaacaagat ttacctaaaa tgaagattga ccaaatggtc
    12481 aatatactag ttttttcaac tgaccaaaag cttactggta gaataagttt tatatctgat
    12541 aaaccatcta ctccaaatac tgaaatggga gctcagcaga atacactatc ttattatgat
    12601 ataaacatag catttgataa tcaagaagga ttagtaaatg gattccatct tcaagcatca
    12661 cttgaagtag ctaattcaag ctttaaaata ccagcatctt gtgtacttaa agacaacaaa
    12721 cactcatatg tatttaagga tttagatggt atattgaaaa agcaaattgt agatgtagca
    12781 agtcaaaatg atgattttgc tgtagttaga ggcggtcttg aacaaggcga tataataata
    12841 aaacacccta ctaaagaaat gaaagaagga gacccagttc aaggcgatgg cgtaactgct
    12901 ggttctaata atggagatac tactccaaac aaaaaagtag aagaagttac tatggatgtg
    12961 aattaattta catatgttaa ttaaattaga aaatattcaa aaatattaca aagtagggaa
    13021 agatgaatta catgttttaa aatccttaaa tttagaaatt gaatctggag aatttgtcat
    13081 gataatgggt aagtctggta gtggtaaaac tactttactt aatatcttag gttttctaga
    13141 tgtatttgat gaaggaagat atatatttga tggaacagat gtaactaatt tgagtgaaaa
    13201 tgaacgttct gtttttagaa atattaatat tggatttgtt ttccaacaat ttaatttaat
    13261 agaaactcta aatgtatatc aaaatgtaga gttgcctcta atttacaata aagcactaaa
    13321 aaaatctaat agagaagaaa ttgttaaaga taaattaagt tctgttgggc ttttggacaa
    13381 gcttaagcag aaaccacttc aattatctgg tggtcaacaa cagcgtgtag ccattgcacg
    13441 ttgcctagca aatgaccctc agataatctt tgctgacgaa ccgactgggg cattagatag
    13501 tgaaactagc agagaaatta tggagctttt aacaaggctc aacaaacaag gtaagactat
    13561 aataatggtt acacatgatc aagatttaac taagtatgca actaaggtta tacgacttaa
    13621 agatggtgtg tttacttcgg aggtgtaatc atgagtttat taaaaaattc tttggccaat
    13681 ttaaaaggtc acaagcttcg tgtatttgta gctttactct ggattataat aggaataact
    13741 tcagtaatac ttgttagttc tataggtaat ggatttcaaa aagaaattaa gaaatctgta
    13801 aacaatgtaa accctaataa aactactatt tcgtttgaat cagccgataa cacaggtctt
    13861 actgatgata tgagtatttt tttaaaacca tttaatgcaa aagatttaga agaattatca
    13921 tttgttgaag gagtagaaag aatagctcct tcaagagatg ggtttaacct tgattcagtt
    13981 tactcttcac aagcatcttt tgataaaaaa actacgtatg ttgatgttgg accagtaaaa
    14041 aaagattcta aaataaattt aatttgtggt agagattttt ctttagatga tgaaaaaaga
    14101 aaagtaattt tacttacatt acaaagtaca agtgaaattt ttgaaaatcc agaagatgcc
    14161 ttaggtcatg gtatcaacat aaatggaact atatttgaaa taataggggt attagatgat
    14221 tctcagcaaa accaagctgg aggattcttt ggaggttacc aagatatgca atttactact
    14281 tccctagtac ctaaaaaggc ttttgacact ttaatgagtc aaaattctta ttcaaatgaa
    14341 atttaccagt tagacttagt ttcttctaaa ggctataatg taaatgaagt tgcaaacaat
    14401 gttatagcta aattatatga gatgcaccct ggtatcaatg gttcttatac tacaccagac
    14461 ccaactgaac agacagctta tcttgaaagc attaattcca atgtaaacaa atatgtatct
    14521 ataataactg tagttgcaat gtttgttggt ggtattggtg taatgaatat aatgtatgta
    14581 tctgttatgg aaagacaaag agaaattggt ataagacgtg ctattggagc aaaacctagg
    14641 tctatattat ttcaattttt agttgaagct gtttttataa cagtatgtgg tggaatttta
    14701 ggaactatag ttggatttac tgctactaac tatgtttcta aatatatagg ttttgaagct
    14761 atacctagct taaatagctt attttatgca attgtagcta ctatattgac tggagttgta
    14821 tttggtctga ttccagcctt taaagcctct aaactagacc ctataaaggc aatttataag
    14881 tagaaattgt ataaagattt tcgattttta gattagttta tataaaacat acttaaatat
    14941 ataacgcact attatatatg atagattagg aacttaatct ttccaaatat aatagtgcgt
    15001 tctttcataa aaaggattct cttccttact atatctaaat taccaagatg ttatgttcta
    15061 attgttcaaa ctaatacttc caattttgat taatcaatct cattctccta atatacaatc
    15121 ttttactttc aatcattgta cactccgcct aaaaaaaata atcttaaatt aggcgttata
    15181 tacaatctcc ccattacata ttgtataatt aacctttcca tataaagatt tacctttaaa
    15241 tggtgaatta tcagctttag aaacaaagct ttcaactgtc cattcttctt ctggattgaa
    15301 tataacaatg tctgctacag ccccttcttc tataaatcca atatttaaat tgtacaactt
    15361 tgcaggattt atagacattt tttctattaa ctgcatcata ctaagatgat ttttatgcac
    15421 caaatttgtt attccaagag ctaaagaagt ttcaagccca ataattccac ttggagcttt
    15481 tataaactct ctatcttttt cttctttact atgaggtgca tggtccgttg ctattatttc
    15541 aatagtacca tcatttaatc cctctataat cttatctctg tcccatttac ttcttagagg
    15601 tggattcatt tttgcatttg ttccaaactc caatacatct tcctcagtca atgtaaagtg
    15661 atgtggtgaa gcttctgcaa ctacatttgc acctaagtat tttgcaaatc taaccatatc
    15721 aacagataca cctgaactta tatgttgtat atcaacttta gcaccagtct ttagtgccaa
    15781 catacaatct ctggctacca taacatcttc tgctacactt gatgcacctt ttaatccaag
    15841 ttctgaagct acctttcctg catttacacc tggatttcca actaaagaag ggtcttcttc
    15901 atgaaaacta agtggtacat ccaactcttt tgccttaatc attgcctcca taattagatt
    15961 gctatccatt aaaggtaatc catcatcagt aaaccctggt acaccagctt ttttaagagc
    16021 ttccatatca actaactctt taccttcaaa acctttagtt atagctgctg cttgtaaaac
    16081 atttatacat gcattttttg acttttcttt aacataatta aaagtatctt cattatctac
    16141 aataggatta gtatttgcca tacatataac agttgtaaat ccacctctag cagcagattt
    16201 agctccactt tctatatctt ctttatatgt aaacccaggg tctctaaagt gtacatgtac
    16261 atccactaaa cctggagcaa ctacattacc actagcatct attatttttt catattcatc
    16321 actttcatca aacttgccta ttttataaat tttattttct tttataatta agtcaatatt
    16381 ctcatctctt tgacttttag ggtctattac tctaccattt ttaattaaaa tcatattatt
    16441 tctcctttat atttttaatt tatatagact catataatat tatacattat tttacatact
    16501 taaatacaaa attacgtttg acatcaatag cctttttagg acaaagttca tggcaacagt
    16561 aacatcttat acatttactt aagtctataa tagcaccctt agtccctatc tctatagtgg
    16621 atgcaggaca agcttccttg cattttccac attttatgca atcttgaaat cttaccacag
    16681 gctttggtgt tataagcttt gaaataggtt catttaaaaa ttttggtagc tttacagaaa
    16741 acaatcttaa atccttactt acatttggaa tcttgtaatt ttttataatt aaatctttta
    16801 tatcttcacc taaaatttca atatctgaaa aatcttcttg tatatatcct ctcttaatag
    16861 cacctctaat tgtagcaact ctatttggaa gtaaacttat aatcttacat gcaacaacat
    16921 ctatagcata tggattttgt gatgctaata aaacgcctat ttctcgagta gtaccagctg
    16981 aaggtccatc accttccata cctactatac catccataat tgtcaatgtt ggttttatat
    17041 aatcacaaat atctaaaagt acattttcgc aaaacaactc ttctgtagga aatctataat
    17101 gtatctctgc ttttttcaat ccagctatgc atccatataa gttttttgta ccaccagtaa
    17161 aagttgccat tatatgagtc tttaatttac aaagatttat tatataatct gaatctacta
    17221 ttggtttaat aatatccata tattttagaa catgtgcttt ttcactatgt atcttaacat
    17281 ctgaaacatc ataatttaac ttaatgccca gttcatttgc tacttcttca attccagatg
    17341 ccttataaat gctcttaaga gaactttgat tatatggacc accagggcta tctgctattg
    17401 taatatcaca atttaactct aaaagttttt cacatacaac ttttacaacc ataggatgtg
    17461 tagttgtagc ttcttcaggc ttttttttca ttaataaatt tggttttata agtactttgc
    17521 ttcctttttt aacaaactta tctataccac caatatcctc taaatttttt tcaatagata
    17581 actttacttc ttcataattg taagttttac aactcctaac agataccgac ttcatattat
    17641 ctccatcctt ctatcacaac agtttatttg tataatttaa aaaaggagaa accaaagttt
    17701 ctccttttaa tctatgtttt aattattatt ttccaaaatg tctgtttaat aatcctaaga
    17761 atgctttacc atgtctagct tcgtctttac acatttcatg tactgtatca tgtatagcat
    17821 ctaatcctaa ttctttagct ctcttagcta attttaattt tccatcagtt gcaccatact
    17881 cagcatcaac tctaactctt aagttttctt ttgtatctgc aactacaact tctccaagaa
    17941 gttctgcaaa tttagcagca tgttcagcct cttcaaaagc tattctctta tacgcttcag
    18001 ctacttctgg ataaccttct ctatcagctt gtctactcat tgctaaatac attcctactt
    18061 ctgtacactc accagtaaag ttggctctta atccttcgat tatttctgca tctacacctt
    18121 gagctactcc tattctatgt tcatcagccc aaaccatttc gcctttcatt tcttcaaatt
    18181 tatcagctcc aactttacat actggacatt gtgctggtgc agcatctcct tcatgtatat
    18241 atccacatac tgtacaaaca aattttttca taattaattt cctcccaatt ttatataatt
    18301 aaatttttat ttttaagttt aataacttgc tacaagaata tatatacccc agactttata
    18361 gcttaaacac taaaaataaa atttatttcc taattaattt tatcactttg aaacaccagt
    18421 atcaaccaag ttttgatgtc aaatttctac ataatacata atttatttga ttaattagga
    18481 aatagttgtc atattaaata ctttctaatg aagactcctc tgaatcttta agtttcactt
    18541 ttttgctctt taaaaaagat aatttagttt ctgcagttat gattgcaaca aatatcaaga
    18601 tactaccaat aaccaatttt gctgtaataa gctcctttaa aattattata gaaaatattg
    18661 taccaaatac agcctctgtg gataatatta tagctgttct agttccatca actctttttt
    18721 gacatatagt ctgaaataaa aatccaattg tagtactaaa tacagctaga tacatagttc
    18781 ccatgtaacc agataattca gcttccatct ttaattgacc tgcaaatgtt tgaactacaa
    18841 cagacattaa aaacgctact gtaaattgaa tagctgtcaa tgccattggg ttgttatctt
    18901 ttgcaaactc acttgtaaag aatatatgaa atgcaaatcc gaatgaacat ataagtgtta
    18961 gaaaatctcc aaaattaata gagaaatcag cttctaaaga aagtatccca attcctataa
    19021 gagctaccaa actacttatt attcctattt tatcaagttt tcttctataa agtataaatc
    19081 ctatgaatgg aactattaca acattagctg ctgttataaa cgcattttta gatggtgtag
    19141 tgtacataag tccaatagtt tgtactgtga atgctagaaa taaaaatatt cctaaaatcc
    19201 ctcctgcttt taataatttt ttacccatat tagcacgaat ctgtttaaaa aacagtaaat
    19261 tcataattat agctgccaag aaaaatctta aagttatgat ttgtagaggt gtaagcccac
    19321 cgtctaatgc aaattgggtt gctacaaagc cacttcccca tataattgct ataaatatta
    19381 gtcctatttc tccaaagtat tttttcaata aagccccctc ctttttattt ttttgcaaaa
    19441 ttataaaccc cctaaacagc aagagagttt ttctataagc attactataa attaatatag
    19501 taaatttttt cagtatttta aatctaaatt tacatacatt ttgagctcaa atttatatcc
    19561 actatttaac agtaatatat taatcatttt ttgtaaacac ctttttaata aatttttata
    19621 ttttttatat ttttttacct atactaaatt tttt
//
LOCUS       DAYAKB010000068        19085 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.068, whole genome shotgun sequence.
ACCESSION   DAYAKB010000068 DAYAKB010000000
VERSION     DAYAKB010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19085
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.068"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..231
                     /locus_tag="ACGI3L_002839"
     CDS             <1..231
                     /locus_tag="ACGI3L_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198536.1"
                     /translation="GKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDGSPQKA
                     STIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            221..745
                     /locus_tag="ACGI3L_002840"
     CDS             221..745
                     /locus_tag="ACGI3L_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198537.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            1057..1614
                     /gene="efp"
                     /locus_tag="ACGI3L_002841"
     CDS             1057..1614
                     /gene="efp"
                     /locus_tag="ACGI3L_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFG9198538.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            1706..2161
                     /locus_tag="ACGI3L_002842"
     CDS             1706..2161
                     /locus_tag="ACGI3L_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1247 N-terminal domain-containing protein"
                     /protein_id="HFG9198539.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            2324..3034
                     /gene="rnc"
                     /locus_tag="ACGI3L_002843"
     CDS             2324..3034
                     /gene="rnc"
                     /locus_tag="ACGI3L_002843"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFG9198540.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            3088..4158
                     /locus_tag="ACGI3L_002844"
     CDS             3088..4158
                     /locus_tag="ACGI3L_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006448 - regulation of translational
                     elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongator complex protein 3"
                     /protein_id="HFG9198541.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            4186..7740
                     /gene="smc"
                     /locus_tag="ACGI3L_002845"
     CDS             4186..7740
                     /gene="smc"
                     /locus_tag="ACGI3L_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFG9198542.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKFAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            7767..9047
                     /gene="ftsY"
                     /locus_tag="ACGI3L_002846"
     CDS             7767..9047
                     /gene="ftsY"
                     /locus_tag="ACGI3L_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFG9198543.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            9150..9518
                     /gene="ylxM"
                     /locus_tag="ACGI3L_002847"
     CDS             9150..9518
                     /gene="ylxM"
                     /locus_tag="ACGI3L_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048500 - signal recognition particle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxM family DNA-binding protein"
                     /protein_id="HFG9198544.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            9515..10867
                     /gene="ffh"
                     /locus_tag="ACGI3L_002848"
     CDS             9515..10867
                     /gene="ffh"
                     /locus_tag="ACGI3L_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFG9198545.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPINIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            10905..11177
                     /gene="rpsP"
                     /locus_tag="ACGI3L_002849"
     CDS             10905..11177
                     /gene="rpsP"
                     /locus_tag="ACGI3L_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFG9198546.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            11242..11469
                     /locus_tag="ACGI3L_002850"
     CDS             11242..11469
                     /locus_tag="ACGI3L_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFG9198547.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            11577..12092
                     /gene="rimM"
                     /locus_tag="ACGI3L_002851"
     CDS             11577..12092
                     /gene="rimM"
                     /locus_tag="ACGI3L_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFG9198548.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            12101..12796
                     /gene="trmD"
                     /locus_tag="ACGI3L_002852"
     CDS             12101..12796
                     /gene="trmD"
                     /locus_tag="ACGI3L_002852"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFG9198549.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            12981..13331
                     /gene="rplS"
                     /locus_tag="ACGI3L_002853"
     CDS             12981..13331
                     /gene="rplS"
                     /locus_tag="ACGI3L_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFG9198550.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            13652..14548
                     /gene="ylqF"
                     /locus_tag="ACGI3L_002854"
     CDS             13652..14548
                     /gene="ylqF"
                     /locus_tag="ACGI3L_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFG9198551.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            14937..16229
                     /gene="brnQ"
                     /locus_tag="ACGI3L_002855"
     CDS             14937..16229
                     /gene="brnQ"
                     /locus_tag="ACGI3L_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFG9198552.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLFVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
     gene            17348..18640
                     /gene="brnQ"
                     /locus_tag="ACGI3L_002856"
     CDS             17348..18640
                     /gene="brnQ"
                     /locus_tag="ACGI3L_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFG9198553.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT         8060 a         1818 c         3511 g         5696 t
ORIGIN      
        1 ggtaaacacg aaggttatgt attgagaaaa gatggtaaaa acattaaatc aataatgcta
       61 cctaaaaatg caaaaatagc taggagtatt gaaataataa agtttaaatc tgatgggtcg
      121 cctcaaaagg cgtctacaat agagatatat aataatagat taagaaaaac tataacaata
      181 acacctgtaa gtggaagagt acttctgaaa gagggaaaat atgaaacata aatatggtta
      241 cttgcttttg gaaagtgtcg tatcattgtc ttcaatggtg ataattatac tagttttata
      301 ttctatattt ttgtctacaa taaacttaaa gttaaaagta gaagataaga tagaactaca
      361 acaacaaagt cttgaaatca taaaatctat ggaaggaatt attagcaatt ctatgggaat
      421 aatgaatgta tctaattatg aagaaacatt taaaaagaca acatctataa aatgtagata
      481 tttagatgaa aataataatg aagaaggcat aagtaataaa gaaattatat tgaatgaaag
      541 acgaaataag ttatttgtaa attctttaaa tggcgaaagt agtcaagcag gtggttatga
      601 aattggagat tatgtagatg agatgtatgt atcaattact aataatggtc aatatgttaa
      661 tattaaattg aaattatcaa aacgtagtca aaaatatgag actgatttca aaataaaagt
      721 atggaatttt agtgaaagta tatagaaata cataaattta agagaaagaa gtgacatcaa
      781 taagtcatat aaaatataat tattgagaac tatataacta aataatatca atatgtaaag
      841 tgtatagatt aagaatatag aggataataa taaaaatata gaataagtaa tttgccaaat
      901 acttgtttat attgtataac ttatgatatt atgatattag taaaaatttg taatcctgac
      961 ttgacagaat tcaagtaaga gatataattt taaaggcata gtaatgtaaa atttactaaa
     1021 aaataagaaa tttattttaa tatggaggaa caaaaaatgg tatcagcagg tgattttaga
     1081 aaaggtgtta catttgaaaa agatggacaa ccatgtttag tagttgattt tcaacacgtt
     1141 aagccaggta aaggagctgc tttcgttaga actaaataca aaaacttaaa aacaggagct
     1201 ataagagaag aaagtttcaa tccaagtgaa aaattcccta aagctgttat agatacaaga
     1261 caaatgcaat atctatacaa tgatggtgag ttatattatt ttatggatca agaaaatttt
     1321 gaacaaatac cattaaacta tgagcaagtt gaagatgcaa ttaagttctt aaaagaaaat
     1381 gaagttgcta caataagatt ttaccaagga caaccattcc aagtggaagc gccaaacttt
     1441 gcagagctag aagttacaga tacagagcca ggtataaaag gtgatacagc aagtaatgta
     1501 actaaagcag ctacagttga aactggagca gttgttcaag ttccattatt tataaatact
     1561 ggagataaag taaagataga tactagaaca ggtgaatatt tatcaagagt ataaaaattt
     1621 atgtatataa aagcttatat gtcttaataa tataagatat atgagctttt agtttatata
     1681 taaaaaagaa agcgaggggt gttacatgaa acatttatat gaagaagttg catacttaaa
     1741 aggcctagca gaaggactag aaataagtgc tgaaagtaaa gaagggaaaa tgatacataa
     1801 aatagttgat gcattagaag tatttgcaga tgctattgta acattggatg aagaacaaga
     1861 agaacttcaa gattttgttg aatctataga tgaagattta gcagatttag aagaagatat
     1921 tgctgacatg gaagaagatc tttatgaaga agatgacgat gaggatgatg aggacttcag
     1981 ctatatagaa atggaatgcc caaattgtgg agagttagta gaaatagacg aagatttgtt
     2041 atatgatgat gaagtagatg ttgtttgtcc tgattgtaag gctgtgatat tatcatcaga
     2101 agatgattgt gatgatgatt gtacatgtgg tggttgttca agttgtgatg atagagagta
     2161 aaaattcata agaattaaaa ctgcctatga tgcctatgag atattttgct tcataggtag
     2221 ttttattttt atgaggaagg gtattatgta ttttggtttt gcaatacttg gacaaaaata
     2281 gtacactaga atttatagaa taggattttg gagggatgta aatatgaaaa taagtaaaaa
     2341 attactagat aatatacaaa gatttgaaaa tgttataaat tataaattta aaaataaaga
     2401 atatatacta gaagctctta ctcatagttc atattctaat gaaaataaaa aatataattt
     2461 taacgaaaga ttggaatttt taggggattc ggttttaggc atagtgataa gtgattattt
     2521 atttaatgaa gaagctaatc tgcccgaagg ggaactaact aaacttagag caaatatagt
     2581 ttgtgaagat tcattaagtg aagtagctaa tgatataaat ttaggtattc acatgttatt
     2641 aggtagagga gaagaagcaa caggaggaag acataggact tcaatattag cagacgcatt
     2701 tgaagctgta atagctgcta tatatcttga tggaggtttt gaaagtgcaa gacagtttat
     2761 acttcatcat atggaaaata taatttatga ttcaagaaaa ggaaatatat ttagagacta
     2821 caaaacgcat cttcaagagg tgttacaagg gaatggagaa aataatatct ggtacaggct
     2881 tatagaagaa aaaggaccag accataataa aagatttgta atggaagttg gaattaatga
     2941 cgatgtactt ggtataggag aaggcaagag taaaaaagaa gctgaacagt tagctgctaa
     3001 aatagcttta aagaaaaaat tatgggaaaa ataaatataa tatgtaaaaa tataaaaaga
     3061 aatatttata ttagaaggat gttgtagatg aaaaagagaa ttatacctat atttgttcct
     3121 cacaaaggat gtcctcatga ttgcatattt tgtaatcaaa aaaaaataac aggtgtgagt
     3181 actgatgtta ctagtgaaga tgcaagaaat ataattgagg aatgtttaga gactatagat
     3241 aaagatgcag atgtagaaat agcatttttt ggtggtagct ttactgctat agatattgat
     3301 atacaaaaaa gtttattatc agttgctaaa gaatatgtag aaaaaggtct tgtaaaagat
     3361 attagaatgt ctacaagacc agattgtatt gatgaagata tattaagtat gttaaaagaa
     3421 tataagacaa gtataattga actaggagta caatccttag atgaaaaagt attattagat
     3481 agtataagag gtcatcaatc tgaaattgta tacaagagtt caaagatgat aaaaaatagt
     3541 ggaatcaaac ttggattaca gatgatgatt ggtcttccag ctgacacaga agaaaagtgt
     3601 atatttacag caaaaaaatt tgtagagcta aaaccagatt gtgttagagt ctatccaact
     3661 ttggtagtaa aagatacagg tcttgaaaag ttaatggaac aaaataaata taatccattt
     3721 actcttgaag agagtgtaaa tatagtaaaa aaagttcttg tactgtttta tgttaataat
     3781 atcaatgtaa taagagttgg gcttcaagct actgatgata tacaaattgg aaaagctgtt
     3841 ttagcaggac catatcatcc tgcatttaga gagttggtag aagcagatat gataaaagat
     3901 tatttagaat ttgttatttt gcaaaataaa aatataaagc aaatgttggt caaatctaat
     3961 aaaaagaata tttctaaaat cataggaaat aaaaaaacaa atgttaaata tatggaagaa
     4021 aaatttggtg tgcttttaaa aacacaagaa tcagatttag atataaatca attagaaatt
     4081 gtgttagatg ggaaaagttt aattagtgct aatatgagag acattcatag aaaattgtat
     4141 gacatttatg acctttagtt ttaataatga agggagagaa aagatttgta tttaaaaaga
     4201 ctagagttaa agggatttaa atcctttcca gtaaaaacag atattatttt taaagaagga
     4261 ataacagcca tagtaggacc aaatgggagt ggaaaaagta atatatctga tgctgtaaga
     4321 tgggtattag gagaacagag tattaagagt cttagaggtg ataaactcga agatgtaata
     4381 tttgcaggta cagatacaaa aaaacctatg aattattgtg aagtggctct tactattgat
     4441 aattctgaaa atcaattgga attagatttt acagaagtaa ctataagaag aagggcttat
     4501 agaaatggtg aaagtgaatt ttttctaaat aataaaagtt gtagattaaa agatataaaa
     4561 gaagtctttt tagatactgg tattggaaaa gatggttatt caatcataga acaaggaaaa
     4621 gtagatgaaa tattaagtaa taatccttta agcagaagaa aagtttttga tgaagcttgt
     4681 ggcatatcaa aatatagata taaaaaacag gaagcagaaa ggaatttaag taatacaaag
     4741 gaaaatttag aaagaataga tgatgtatat atagaaattg aaaatcaatt aaagcctctt
     4801 tttaatcaac agacaaaggc aaaaaagtac ttggaaataa gtgaaaaatt aaagacactt
     4861 gaagtaaata gctttataag agaaattgaa ggaatagaaa aagaattaag tgaggttaat
     4921 gaacatcgta aggttattga aaaggagctc aatgaaaaag aagaacaaaa aaatgttgta
     4981 gagaaaaagc aagaagatat taataaagag gtagaggtat tacaagatgt aattgaaaaa
     5041 tctgtagatt atataaattc aattaaagga gttatatcaa aaaaagagtc ccaaataaat
     5101 ttaattaagg aaagaataag aaattttacg aatgaaatta gtagaaaaaa tttagaaata
     5161 aaggatataa aagagaagct aaatgaaaat aagcaataca taaaagaatt agaaagcaat
     5221 aaattatcag gtagtgaaga actatctacc ttgcaggaaa atataaaagt attggaagga
     5281 agtaaagata aacaaaaaat taagttagaa tccctaaata atgagataga attattgaaa
     5341 gaaagtataa ttgatatatt aaataagaaa caagagttta gtaataagct gtctacttta
     5401 aacgcaaata aagaaaatat gaatatcaga gatgaaaata taaattcaga gataacagag
     5461 ttaaacaaaa atattgaaat aaaatcatct gaattagata ctataaataa agaatttaat
     5521 atgcaaaatg aaaatttaaa gaatgtaaat aatagacata aagaattatc aattaatttg
     5581 caggattcaa ttagtgaaca caataaacta gaagatgaaa tacagaaaag taaatataat
     5641 ttaaatggat ataattcaaa gttaaatgtc tatatagata tggaaaatca ttatgaagga
     5701 tttaatagag gagtaaaaga agtactaaaa aataaaaatt taaaaggagt tcatggagca
     5761 ttaggacaga ttataaatgt acctgaaaag tatgagaaat ctatagaagc agctcttggt
     5821 gcttatatgc aaaatataat aactgataat gagtttagtg ctaagtttgc aataaactat
     5881 ctaaaacaga ataatttagg tagagtaaca tttcttccat taaatataat taaatcaaat
     5941 aaaataagtc taggaaattt aaaagcaaat actaagttca taggaatagc aagtgattta
     6001 attacatttg atgaaaagta tagaaatata attgaaaata tacttggaag aacaatactt
     6061 ataaataata tagatgaggg cataaaattt gcaaaagaaa ctggtcatag gtttaaaata
     6121 gtaactttag atggtgaaat cttaaatcca ggaggttctt tgactggggg aagtctaaaa
     6181 actaatggga atatactatc gagaaaaaga tacattaatg aatatacaga aaagataagt
     6241 aatatcaaga atgaaatttc acatctagaa ttaaaaagag aatctttaga caaagatgtg
     6301 aaaaatatca aaaatgaaat tgattcacat gaaagtaaaa taaaagattt agaaaaaagt
     6361 ataataataa aaagtacaag tataaagaat gttgagtctg aaattgaatc gttaaaaggt
     6421 agtattacta aattagaaaa tgagaagaat gatttaaatt ctaacctaaa ttatacactt
     6481 gaaaaaagtg atgatgttag aaaagatatg gaagagttag atgatttata caataaaaat
     6541 aaagaaaaaa ttgatgcatt gaatgaggaa ataaaaagat acaatgattt atatgataaa
     6601 gaaaaatctg aatttgatga attgaactta agtttagtga agaaaacaga agtttacaat
     6661 agtatagtta gagatataaa aagaatatct ggtgaaaatt gtgagctaga agaaaaaaat
     6721 aaacaattag aagagtcatt aaattatgaa gaacatgaaa taattaaatt acaagattct
     6781 atactcactg aagaaaaaga aaaagaaaat ttaacaaaac aactagggga tagtaataga
     6841 aatcttgaaa ctagaaaaat agcaaaagat gatttaaaaa atagttttga tgaaattaat
     6901 aaagaattaa aaactataga tagacagcat atagaactta aagaaagttt atttaaagtt
     6961 ggtggaagat tagaaagatt aaaaactagt caagacacat atataaataa gttgtttgag
     7021 caatatgata tgaccttagt acaagcattg gaaattaaag atgaagattt ggatatagat
     7081 agaaaattct tagaaagtct aaagagagaa ataagaagtc ttggaaatat aaatatagac
     7141 tctataaagg aatatgagga aataaaagaa agatacgatt tttatagcga acaaaagcaa
     7201 gatttagaag agtctatgga agagatagaa aaacttatac atactttaga agaaaatatg
     7261 aaatctgaat ttgaaattaa gtttgaagaa ataagtaaaa attttaaata tgtatataag
     7321 agattatttg gtggaggttg tggagaatta actattttag ataaagaaaa tttattagaa
     7381 agtgatatac taataacagc tcaaccccca ggtaaaaaaa tgaaaaattt aaacctatta
     7441 tctggtggag agaaagcttt aacggcaata agtatattat ttgctatatt gattacaaag
     7501 ccaacaccat tttgtatatt agatgagatt gaagcgccac ttgatgacgc aaatatattt
     7561 agatttggag aatttttgaa ggatttatct aaagagactc aatttatatc agtaactcat
     7621 aggagaggaa caatggaagc tgctgattat atctacggag ttacaatgca agaaaaagcc
     7681 atttcaaaag ttattagttt aaaattaaaa gaagctcagg aaataacaga tattatataa
     7741 cttagattga cataggagga ataacagtgt taaaaaaatt atttggtttt ggaaaagaca
     7801 aggaaaagga aatagaaaaa aaagatgctg aagaagaaat agaagttgaa gacagtgttg
     7861 ataatttaga aaacttggaa gaaactattt tttcaggact tgaagaagaa gtgatagata
     7921 aagtggaaga tattgaagaa aaaaatgagg aaagtgtcaa taatgaaggc actgaagaaa
     7981 tcgaaaactt tgaaaaaata gaagttgaga tggatagtaa tggaaaagaa gtagaaaata
     8041 tttcaaataa tgattctcaa gaagagataa tcgaagaatt agaaaattat gatgaaattg
     8101 agtctaaaga gatagaagat aaagaagata agaaagttaa cttgtttgaa agactaaaac
     8161 aaggattgac aaaagcaaag caaggaataa ctgatagaat agatgaagtt ttaaaatcat
     8221 atacaaaaat agatgaagaa ttacttgaag atttagagga aattttaata acagcagatg
     8281 ttggtgtaaa tacaactatg gatataattg aaagactaag agataaaata aagcaaaaag
     8341 gtattactga accaataaag gtaagagaag aacttaaatc tatagttgaa gatattctta
     8401 caaatgaaaa ctctacacta gatatagaac cagcaccatg tataatatta atggtgggtg
     8461 taaatggggt cggtaagact actacaatag gtaaactagc aaatagatac aaaaaagatg
     8521 gtaaaaaagt tttattagca gcagcagata catttagagc agcagcgaca gagcaattag
     8581 aaatttgggc aaatagaacc aatgtagaca taataaaaca tcaagaggga gcagaccctg
     8641 gagctgtagt atttgatgct ataaaagctg caaaagctag aaaaacagat gtattaatat
     8701 gtgatacagc aggaagatta cacaataagg ctaatcttat gaatgaactt ggaaaagtat
     8761 ttaaaatagt agatagagaa tttccagaag caaaacgtga agtacttctt gtggtggatg
     8821 ctacaacagg tcaaaatgca gttgttcaag caaagacatt taaagaagtt gcagatataa
     8881 caggtatagt acttacaaaa cttgatggaa ctgcaaaagg tggagtagtc cttgcagtaa
     8941 aatcagaagt agatgtacct gtaaaactta ttggagttgg agaaagtgta gaagacctac
     9001 aagatttcaa tgcaaaatca ttttcagatg cattatttgg taactaatgt tcttttaaaa
     9061 ataatggttg acaagagtgt tgttatgata taaaatacaa tagtgtaaag taaataacct
     9121 ttacagtata ctgctaggaa gtgtaagata tgaatataga aaaaatggtc gaaattggat
     9181 tgttatttga acagtataaa gaattattaa ctgacaagca gaaagaaata gttgctctat
     9241 actatgaaga agattattct ttaggtgaaa ttagtgaaaa tctgaatgta tcaagacaag
     9301 gtgtttatga taccttaaag cgttcagaaa aaatactaag agattatgaa gaaaagttac
     9361 acttagtatc aaagattcaa gagcaggaaa aaaatattaa gattataaaa gataaaatta
     9421 ttgacattaa agaagattta ttgcacaata gagattgtgc taatttaatc cctaagctag
     9481 aaaatataga agatgtatgt agggagatga taaaatgata tttgaaggat tgtctgataa
     9541 actacaaggg gcatttagta agttaaaatc taaaggaaaa cttacagaag tagatgtaaa
     9601 aaatgctatg agagaagtta aacttgctct tcttgaggca gatgttaact ttaaagtagt
     9661 taaagatttc ataaaaaaag ttcaagagag atgtgttggg caagaagtta tgcaaagctt
     9721 aactccagct cagcatgtaa tcaaaattgt aaatgaagag cttacaagtt taatgggaga
     9781 tgtacaaagt aaagtaatga tttcctcaaa gcctcctaca attttaatga tggttggatt
     9841 gcaaggtgca ggtaagacta ctacagcagg aaaacttgga ggatatttta aaaagcaagg
     9901 taaaaaacct ctattagtag cttgtgatat ttatagacca gcagctataa agcaacttca
     9961 agttgttgga gaaaaattgg atatacctgt attcaatatg ggagataaag aaaatccaat
    10021 aaatattgcg aaagcaggtt taagccatgc gattaaaaat gctaatgatt tagttattat
    10081 agatacagct ggtagacttc atatagatga agtacttatg gatgagttaa agtctattaa
    10141 atcagaagtt aagccacatg agatactttt ggttgtagat tctatgacag gtcaagatgc
    10201 tgtaaatgtt gcagaaagct tcaatgaggc acttggtgtt gatggagtag tattaactaa
    10261 attggatgga gatactagag gtggtgctgc gctttcaata agagcagtta cacaaaagcc
    10321 tataaaattt atggggatgg gagaaaagct agatgatata gaacctttcc acccagatag
    10381 aatggcatca agaatattag gtatgggaga tgtcttaagt ttaatagaaa aagcacaaga
    10441 aaatatagac ttagagaaag ctaaagaatt agagcaaaaa attaaaaaac aagagcttga
    10501 ttttgaagat ttcttacaac aaatggaaca aatacaaaat atgggacctc ttgacaagat
    10561 acttggtatg atacctggta tgggaaatgt aaaagaccaa cttggagatg tagatttgaa
    10621 tggcaaagaa atgaagagaa caaaagccat aattcagtca atgactacat atgagagaag
    10681 aaacccagga gtattaaatg cttcaagaaa gaaaagaata gctaaaggca gtggaactag
    10741 tgtacaagat gtaaatagac ttataaaaca acttaatgaa atgaaaaaaa tgatgaagat
    10801 gtttgctggt tcacaaaaga gtatgaagaa aaggggcggc ttaggcggtt tacctttttt
    10861 taaataaaat ataaaaaagt aaaaattatt cggaggtgac tgtaatggca gttaaaataa
    10921 gattaaaaag aatgggagct aacaaaaaac ctttctacag aatagtagta gctgattcaa
    10981 gagctccaag agatggaaaa tttatagaag aaataggata ctataatcca atttctgaac
    11041 ctaaacaagt aagaataaat gatgaaaaag ctataaaatg gttagctact ggtgctcagc
    11101 caacagaagt agttaaaaaa ttacttgtaa aaaacggagt aatagaaaaa ttcgaagctt
    11161 ctaaacaagc aaaataattt tttcttggca attagtttaa gtaagggctc attgctaagg
    11221 ttactttagg agatgaaata tatgaaagag ctagttgtag atatagctaa ggctctagtt
    11281 gataatcctg actcagttgt tgttgaggaa tttgaagata atgatggtat cgtcttaaag
    11341 cttacagttg ctcaagagga tatgggtaag gttattggga agcagggaag aatagctaaa
    11401 gctataagaa ctgtcgtaag atctgttgca aatagagaaa atataaaagt ttctcttgag
    11461 atagtataaa ataggaggat taggtataat gcctagtcct ttttatataa atgcgtagtt
    11521 taagatttta tgatgatatg accacataag attaaatttt ttaagaaggt gataacatga
    11581 aagaaaaatt aactcatttt aaggtaggtc aaatagtaaa tacacaaggt ttaaaaggtg
    11641 aagtaagagt ttatccgctt actgatgata tagagaggtt tgatgaatta aaagatttct
    11701 atctgggaaa agatttaaat aataaattgg ctgttgaaaa agtaagatac aaaggttcta
    11761 tggttataat gaagataaaa ggcatagaca gcatagagaa agcagaaaaa ctaaaaaata
    11821 aatttatgta tgtagctaga gaagatagca gagagcttga agaaggcgaa ttttttatag
    11881 cagatatgat tggaatggaa gttttaactg tagatggaaa atatgtaggg atactagaag
    11941 atgttcttca atactcagca aatgatgtct atgtagtaaa aggtgaggaa gataaagaat
    12001 ttatgatacc agctataaaa aaatttgtac ctacaataga tattgatgaa agaaaaatga
    12061 ttatagaccc tattaaggga atgatagatt aggtggtaat atgagatttc atataatgac
    12121 actttttcca gaaatattta attcgtacat ggatgaaagt ataatgaaga gagcagttga
    12181 aaaaggtata attgaggttc atatatataa tataagggat ttttctaata ataaacataa
    12241 aaaagtagat gattatccat ttggaggagg agcggggatg gtaatgactc ctcaacctat
    12301 atatgacaca tataagcata taataacaac tcataatata aataacccaa gtgtaattta
    12361 tcttactcca aaaggtaagg tatacaatca atctatggca aagcagatgt ctttaaaaga
    12421 agatataata ctactatgtg gtcattatga aggaatagat gagagaatca ttgatttaat
    12481 agttactgat gaaatttcaa ttggagatta tgtattaact gggggagagc tcccagcact
    12541 tataatgata gattctatat cgagattaat accaggtgta ttaaaccaag aagaatcatt
    12601 tgaagaagaa tcatttaaag acaacttatt ggaatatcct cattacacta gacctagaga
    12661 ttttgaagga ttaaaagtac cagaagtgct tttatcaggg aatcataaga agatagatga
    12721 gtggagaaga gaagaatcta taaggataac caaagaaaga cgatttgatt tatataaaaa
    12781 atctaatgaa aaataaaaat ataatgaaaa attaatatat atgtatacaa taaagtacct
    12841 ataaatggaa ttaaaaacat aaaagtgctt gtaataacta ttgaagtata gtataatata
    12901 aaatgttgaa aatacgggcg ttcctctgtt tacactggtc gggtagttaa gaacgtctat
    12961 gatatctagg aggaagaaag atgaatgaaa tgctaagagc aattgagcaa gaacaattaa
    13021 aaaatgaagt tcctaatttt ggacctgggg acacagttaa agtacacgtt agaattatag
    13081 aaggaaaaag agaaagaata caagtattcg aaggtgtagt attaaagaga caaggtggag
    13141 gagcaagaga aactttcaca gttagaaaaa tgtctttcaa tgttggtgta gaaagaactt
    13201 tcccagttca ctctccaaaa atagaaaaaa tagaagttac tagaaaaggt aaagtaagaa
    13261 gagctaaact aaactactta agaggtagag taggtaaagc tgctaagata aaagaagcta
    13321 gaaataaata attaaaaact ttacttataa atggggggct gatttatcag tcctctttct
    13381 attttaatga aaattacagc aaataattat actagaaata aatagaaata tttgttgaaa
    13441 atatacatta tttatctatg aatttatagc ttttaaaatg aaaaataaaa ttggtaaata
    13501 ttgcattata ttttgtaaca atattaaaaa taagagaaca gtattatgta aagtatgacg
    13561 ttaaaaagat gacaatatta tagtttgtta agatagattt tttaagtgga attaggatat
    13621 aataatataa tattaataag gagtgataca tgtgtcaaat gaatacgaag agtatcttat
    13681 gaatgacaat ctacatataa actggtatcc aggtcatatg aaaaaaacta aggagttagt
    13741 aaaaaataac ttaaaattga ttgatgtagt aattgaactt ttggatgcta gaatcccgtt
    13801 tagtagtaaa aatccagaca tagacaggct tgtaggagat aagccaagag ttgtcgtact
    13861 taataagagt gatatggcag atagggataa attgaatcaa tggattgaat actataagaa
    13921 aattaatatc aaagctatac cagtagatac aataaaaggc gttggtataa ataagataat
    13981 cgaagaatgt aaaaatgtaa ctagagaaaa aatgagttct ttaaaagaca aagggagaaa
    14041 agaaagagct atacgaataa tgatagttgg agttccaaac gttggtaaat cgtctcttat
    14101 aaacaaatta acaggtagaa aaagcactca aactggagat aagccaggag taacgaaagg
    14161 gaaacaatgg gttagattaa agggaaatct tgaactttta gatacacctg gaatactttg
    14221 gcctaagttt gaagaccaag aagttgcatt aaatttagca tttagtagag ctataaagga
    14281 tgagatttta gatactgaaa ctttggcttt aagacttata gagaaactta tgaaaataga
    14341 acctgagaag ttgaaagcca gatataagtt agattgtcta ggagaaactc caattgaaac
    14401 tatggatatg attggccata aaagagggtt tataacaggt aaaaaagaac tagattatac
    14461 acgcatagcc acaactgtat taaatgaatt tagagatgga aaaataggaa atataacatt
    14521 ggaagttcca gaaaacgtta aaagatagat tttaaaacaa aatcaaaaat ttaatgttaa
    14581 aaatttaaaa aagcctttta gcaaaggctt ttttattttt ttgaaatata gacaaatatc
    14641 tccatataaa agtataaatt aggttagaaa acctttaaaa atattaattt aagacaaata
    14701 tacctaatat tttgaaaatt aaaatgagtg tgattattta aaattttagc atattgactt
    14761 gcttgtttcg tataatatat aataagcaca aataaataca atatattaaa aatttaattt
    14821 atttaatttt attaatttaa taataagttc ttattgttta attcaactta cttatgcaag
    14881 cgtaaacaat cgagacattt tattaattta ataaggttaa aaagggggat tttataatgg
    14941 gtaagaccaa ggatgttata gtatttggat ttgcgttatt tgcaatgttc tttggagcag
    15001 gtaacttaat atttccacct tacttgggaa taattacagg tccagaatgg ttaattgcct
    15061 tcttaggatt tacgtttgct gatgctggat tggcacttct agcagtaatg gctacagcta
    15121 aattcgatgg aaacgtagtt gaaatgttta aaagatgtgg tatgaagtta ggaattctta
    15181 taggttgtgc agatatttta tgtataggac cattcttagc tataccaaga acaggtgcaa
    15241 caacttatga aatgggtata atgcctttgt ttggaacttc aattccagtg ttattattct
    15301 gtatactttt ttttgcgatt tcatatgtac taacaataag accttctaag gtcgtagata
    15361 tagttggaca gtttttaact ccagctcttc taatagcttt agcatttata attataaaag
    15421 gtattatatc acctcttgga gatatagtag ataaacctat gatacctaat gtatttgcag
    15481 aaggtatagg tcaaggatat cagacaatgg atgcttttgc agcaatagca cttgcatcag
    15541 tgctaatagt atctttaaat gataaaggat attctactat tagtgacaag ttgaaaatga
    15601 ttggtaaggc gggtgttctt gcttgtggag gattagctct agtttatgga ggattatgtt
    15661 tccttggggc aactgtatca acaatgtatg gaacagatgc agtacaatca caagtaatag
    15721 taaatataac tgaaggattg cttggaaatg ttgggaaagc gattttagca gtagtagtat
    15781 cattagcatg tttaactaca tctataggtc ttacatctgc cacaggtcaa tatttctcta
    15841 gacttacaaa aggtaaattg agttatgaaa aaatagtatt agctgtatct gtattcagtg
    15901 cagtagtagc atcttttggt gttggaacta taataaagat agcatctcct atactaagta
    15961 tagtttatcc accatcaatt gttttaataa ttttagcttt cttcaatgaa aaaattaaga
    16021 atgataatgt atacaaagga gcagtatata tgtcattgtt tgtaagtata ctaacagtta
    16081 tatctagtta tggagtagct gttccagtag taaattcttt acctcttaat tcattaggat
    16141 ttaactgggt ggtgccagtt ataatagctg gaataattgg taattttata ccatcaaaga
    16201 gtcaatctaa tacacttgga acaaactaag ttttgtttaa ttaaaatata atcaattgta
    16261 aataaatgag ttaactaaaa gtaaaaggag ttatttgtac aaataactcc ttttattttt
    16321 agattctata tttaattatt tgtatttaat atggaaaaag tataagaaaa tatcaaaaaa
    16381 atatatggtt tattttttaa caataataga gattaaaaaa gaattttaga gtaattttat
    16441 aaatttaagt atacatatta aatgattttt acaaaaatat aatataaata aaattgtgac
    16501 aataataaaa taataaaaca aaatttaaga catatgatta tataaatgta ttaaataaat
    16561 gagtaaattg ttttcattga gagatatatt aagaattttt agttaattat gacatataag
    16621 tatgtaaacg tgaatactag caactgcaaa gtttaagtaa gttggaagtt agagagtaat
    16681 tgttatgaag aaaaataagt tgataaatca taataaggaa ttttcagaaa aaatggtttt
    16741 aagagtaaaa aacaagaggc aaatctacgc aagtagaata aaaattgaat aaagttaact
    16801 gtcaatttag caaaataaat acaaaatact acaagaatta acgtaaatag gtgttatgat
    16861 aaaaggaaaa cgatttttta agaatcataa ttttgaaaat taaaaaaatt aaaaatgcta
    16921 ttgactgctt ttttttcaga ttatataata aacacaaaat atttaaaatt taaattgaat
    16981 taaaaagatt atatgaatgt aaaaaaggac agtgatatat acagtatata aagcaataca
    17041 acttaataat aaatcgaata atctaaaaag tcttaatatt ttaattattc ggaatagtta
    17101 attttatcaa gaaaaattag agaaaaaaca aaaaaccaac tatgtttaaa gtatacaggt
    17161 tgattttgtt taattaagaa agttgtatta aatattgtga agattttata aattatgaaa
    17221 cataattgac aaatttaagt caaaaatgta taattaaata aaatctcgtc aaaaggtttt
    17281 catttaatta agagattgga cttatttttt agtaaaaggt agtaaaattc aaatgggggt
    17341 gctttaaatg ggtgagaaac aaatcaattt taaagatgta attgtaattg gatttgcact
    17401 atttgcaatg ttttttggtg cagggaactt aatcttccct ccatatctag gagttttatc
    17461 tggaagtagt tggctagtag ctttcatagg attccttttt gcagatggtg gtttggcatt
    17521 attagcagtt atagcagcaa ctaagttcaa tggagacaca tcgaagatgt tctcaagggc
    17581 aggcaaagga ttaagtattg cattaggatg tgcaatggta atctgtatag ggccactttt
    17641 agcaatacct agaacagcag caacaactta tgaaatgggt atattaccta caataggttc
    17701 tggaataagc ccagtaatat tctctatagt attctttgct ctagtattgg ttttaacaat
    17761 aagaccatca aaagttgtag atatagttgg gtcaatatta actccagctt tacttatagc
    17821 tttagcagta ttaatagtta aaggtatcgt atctccatta ggagaaataa gagacagttc
    17881 tttaatacaa aatgtatttg cagaaggtat aactcaaggt tatcaaacaa tggatgcatt
    17941 ggcagctagt gtatttgcat caattataat catgtcagta atagctaaag gttatacagg
    18001 tgagaaagaa aagatgaaag ccacaataag tgcaggtgta attgcagtaa taggaatggc
    18061 attagtttat ggtggattat gttatcttgg agcaactgtg tctcaacaat atggacaaga
    18121 tgttcaacaa acagctttaa tagttgcaat aacagcagct ttacttggaa ctacaggtaa
    18181 aattttattg gctattatag ttgcattagc atgtttaaca acagctatag gtctttcttc
    18241 agcagctggt caatatttct caacacttac agatggaaaa ttaaagtatg agcatatagt
    18301 tatagtagtt tgtgtattta gtgcaatcat atcaaacttt ggagtaagta caataataca
    18361 attctcttct cctatactaa gtatggtata tccagcaact ataactctag ttatactagc
    18421 attatttagt aataaaatta aaaatgacaa cgtgttcaaa tgtgctgcat acatggcatt
    18481 attagtaagt gtattaacag ttgcaacaag ttttggtgta aaaattcctc tagttaatag
    18541 cttaccattt gcttcattag gatttaactg gatagttcca gttgtaatag caggaataat
    18601 aggaaacttt attccatcta aaagcagtaa aactgcataa taataaaaac taattgataa
    18661 ttatggaatt gcctttaaat tatataggca attccttttt atatttaaaa gaattattaa
    18721 attattgtag ataaaagaac attattaatc ctgtttgata aatttaaaaa tttatttttg
    18781 aagtagtatg atttataaag ataataaaat aaaaaagatt catttataat tataaataaa
    18841 attaaattat atattataaa tgtttagtat taatataaaa acatcaatac atatttttgt
    18901 aaagaaaaaa taaagaattt attttctaaa tacttattaa ttaatcaaag ttaaaatgaa
    18961 aaaaatataa aaagataaag tatataagag tataatttga cttttatata cttttttata
    19021 ttatttttga gttttttagg aagatatttt acaagttaag aaaactataa ggagtgttat
    19081 attga
//
LOCUS       DAYAKB010000069        19062 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.069, whole genome shotgun sequence.
ACCESSION   DAYAKB010000069 DAYAKB010000000
VERSION     DAYAKB010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19062
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.069"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(297..833)
                     /locus_tag="ACGI3L_002857"
     CDS             complement(297..833)
                     /locus_tag="ACGI3L_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFG9198554.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(851..2164)
                     /locus_tag="ACGI3L_002858"
     CDS             complement(851..2164)
                     /locus_tag="ACGI3L_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HFG9198555.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2519..2959
                     /locus_tag="ACGI3L_002859"
     CDS             2519..2959
                     /locus_tag="ACGI3L_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HFG9198556.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(3143..3331)
                     /locus_tag="ACGI3L_002860"
     CDS             complement(3143..3331)
                     /locus_tag="ACGI3L_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9198557.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4353..4748
                     /locus_tag="ACGI3L_002861"
     CDS             4353..4748
                     /locus_tag="ACGI3L_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HFG9198558.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4791..6890
                     /locus_tag="ACGI3L_002862"
     CDS             4791..6890
                     /locus_tag="ACGI3L_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFG9198559.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNTSTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(7115..12325)
                     /locus_tag="ACGI3L_002863"
     CDS             complement(7115..12325)
                     /locus_tag="ACGI3L_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HFG9198560.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSMDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12340..14835)
                     /locus_tag="ACGI3L_002864"
     CDS             complement(12340..14835)
                     /locus_tag="ACGI3L_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198561.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15496..15783)
                     /locus_tag="ACGI3L_002865"
     CDS             complement(15496..15783)
                     /locus_tag="ACGI3L_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198562.1"
                     /translation="MRLNITKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNIFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15803..16078)
                     /locus_tag="ACGI3L_002866"
     CDS             complement(15803..16078)
                     /locus_tag="ACGI3L_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198563.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16733..16912)
                     /locus_tag="ACGI3L_002867"
     CDS             complement(16733..16912)
                     /locus_tag="ACGI3L_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6440 family protein"
                     /protein_id="HFG9198564.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(17197..18672)
                     /locus_tag="ACGI3L_002868"
     CDS             complement(17197..18672)
                     /locus_tag="ACGI3L_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198565.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
BASE COUNT         6345 a         3314 c         2077 g         7326 t
ORIGIN      
        1 gcttaattac tatttactat atattattca tttttaaata aaatgtgatt attttttatt
       61 aaaaacgata taaatataca atttaatact atttttttat aaataaactt gtattaaaat
      121 acatttagtt atataatttt attttttcta agagtataat tataaaaata aaaaaagaat
      181 aggataattt tcctactctt ttttctgtac ttacatataa tattaaaact ctttattttt
      241 taatatatat tttaaatttt cttttttaat aaatcttttt cttttaataa atctatttaa
      301 ttttcttctt ctatatcaga gccaaaggga atccatgcat taccaaactc tttatcttta
      361 aataaataag ctaatccagt tatttgcttc aatctaagaa tttcatcaac ttccataccc
      421 aggtgctttg atatccattc atcagatttt ccaatttcac aaagttcagt tataatttta
      481 ctcattaaat ccacattatg agaacctctt gcacgattgt gtcgaatagt acttgccatt
      541 ctttcatcaa gagatttatc aattactgaa acaggaagaa gtccattttc tctatcatat
      601 atatcctcat tttcaagcat tactctatat ctatgaaaac catctacaat aatatactta
      661 tccttttcct cattataata acagacaatt ggcattgtat acccatcttc ttttatactt
      721 ttatacaaca actgcatttc tggtggggct actgcatttg gattatagtc gttagattct
      781 atcttttcga ttggcactgc gatgattcca tatacaggac ttttatattc catagcatct
      841 taactcctat ctaatgaatt ttttcatatt tcttcttaat atattccgtt ctaattctct
      901 gttcttttgt aggaccaaat cccataaatc tacacatatg gtcatttttt aaaatacaat
      961 aacacattct tttccaactt ggtatatctt tggtaaattt aatatcatcc gtatcatcag
     1021 gtatatcatc caaaaatatg actctactct ttttatcttt tgtatgattt gaaactccat
     1081 ttaattctat tttataacct tttctcaaca attcacgtat aactatttct gacaaaccac
     1141 cacctgtatt ctgccaaaac tcaatagatg ttgaaaattt tttaatatag ctattcctta
     1201 tattttcagg taaggtatca agcaaaaaat atgtgaaact tttccatgtg tgtccatatg
     1261 gcaatttaac actacgatat cccatagctt ttgttttgcc ataaatagaa gtaaaattaa
     1321 ctccttgtac tctagcaacc aatttcaccc atacatctgg gtccaatatt ctgtataaat
     1381 ttaaactctc ttttgctgaa tcattaaaag gtgatgccac tctcattttt cttggagcta
     1441 ctccagcttt atagaataag tcataaattt tattatagtc atagtcaaat ttatagtgtg
     1501 ctaaccatat atcttctatt tcccaatcat atataggaga tgccgtccag acatttttaa
     1561 attccttagt tatccagcac tttcctttat atccatgctg tttattcaca atagaacaat
     1621 aacgttgtag agattctgct gctcgtgttc ctaataagca aacaactttt gcaccttcat
     1681 gtatatctct aatccatcta ccaaattgtt ttgccaaact ttcttgtctc attttatatt
     1741 tataataagt aaaaggatta tttttttgat ttattatgta ttctttgact ggcatttccc
     1801 ttacccataa ctcttctttc tcatcatccc atggatacca atacatttca taatttccta
     1861 cagcagttct tgtagccatt ggtaaacaca cccaatatgg ttcaatatct tcaatattat
     1921 cttcaaatac tttttcaaca tattcagtag tcaaactata ttgagcctca aaatcttgat
     1981 gaaatactcc tattttggaa cttatattat tctttctctt ataatccaaa actaaattta
     2041 gcagtaaacc actatctttt cctccgctaa aagatacata gatataatca aattcattaa
     2101 aaagataaga aagtctttct tgaaaagctt caaatacatc ggattctaaa tatctcttat
     2161 ccatttgaat tatccccttt caattagaag tttataaaac cttacaatgc aatattatta
     2221 tgctttttta gcagtaatca gcataaatta tacattattt aaatacacaa atccaactaa
     2281 ctacatataa ttataatgta attatacttt tgtattataa actatatttt atcattattt
     2341 tacatttttt tccaatatat ataaatatca tatttttcta ttagctaaaa ctaattactt
     2401 tatatttcta cgtattagta taataataca taaaaacttg aataatgcat aaaaacttga
     2461 catactgttg tcataattac tttgctataa ttaaaagtaa aaatggaggt aaattctaat
     2521 gtatgaacgt atgcttgata aaagcaataa accctgtttg tcccaaataa tagaatatat
     2581 aggtaaagat ggatatgcac gattgtgtaa gttggaaact tacttgaaaa ctcaatataa
     2641 tttatcaaga gaacttcgat ttccttttgg aaacaattat ggttggggtt acaaatatag
     2701 ccataaatct tttcatttat tttatgcttt ttttgaaaaa ggtgcattta ctgttctgat
     2761 tcagataggt gacaagcaag ttccagcagt agaaaaaacg ttggtagctt tgacaccaaa
     2821 agctaaagaa ctctgggtca ctcgttatcc ttgtggcaat aatggaggct ggattaagta
     2881 tcgtatttta gaagatgcag acttacttga tattattcaa tatataagag caaaaaaatc
     2941 tccacctaaa caaaattaac ttttattttt tgtgatttaa atatagtgta tataaattcc
     3001 attctttcca tattaaaaaa taatataaaa aatatctatt agtataactt atttagtatg
     3061 tcttattcta ctttttacag ataattaaaa agttttatca taaataaatc ataactagac
     3121 atcctagtaa atcaaaatta atttattctt ttttattcga atttttgata atagtcccta
     3181 tacatatgcc aattatcatt ccaaaaatta gaccataaca cattgtaata cctacatttc
     3241 ctttagaaat acctatagca caacctatag ccattccaag tatcatgcct ataaacatac
     3301 atataataac taaattgttg tttttattca tagtttttct ccattcaata tattttaaat
     3361 tgcctagctc gccttcttag cttaaaacaa agaaatataa attaactttc tttcattcta
     3421 atatctgcct gtataaatgt caaacaacac atttcttgtc ataacctcct ctttttgaag
     3481 taagtacaat ctcccagacg caataatatc aatttcctaa aaccatttaa gtaactttta
     3541 tatttacata atatttacaa tcataaacta tattgttatt catttataca tcataaacac
     3601 tccctcctaa tcattattat acttaaaata atgttcattt ataataatat atctaacgca
     3661 ctttaattga aaaaactaaa actttgcctt tcattcccat atataaataa gtatactttt
     3721 tgatgctcta ttacaaatca actaaattaa ttgatataaa ttatcatttt ctgttgaaaa
     3781 taccattcgc acatgctata cttaattgca taaatggtaa taaatgtcat atgattttac
     3841 aaatctatta ataacaatta ttacttttac tgtattttaa agtttttgga ctaaatatca
     3901 agaactttct aaaatacaaa gtacaaaaaa tttatataag ttataaattt atatgaacta
     3961 gataagctca aacaatatgt tatgtataaa ctgtgtagta ttcggttata aatttatata
     4021 aattatataa gctagataaa gtattacctc aactatataa gctagatata taaattgctt
     4081 atataagcta gataagaatt atttcaacta tataaactac atatataaat tacatacata
     4141 agctagatat ataaactgca tatataagct atataagaat tatttcaacc atataaacta
     4201 cacatgtaaa attcatataa atttactaat ataaatcaaa taaaattact aaactctcta
     4261 aactaatttt gtaaaacata ctctattttt aacatttgtt accttataca taagtacaaa
     4321 caaaatctaa ctaaatgaaa ggataatgta aaatgaatat tttaaaaatg aaaaaaacag
     4381 ggatattttt aggaggagta ctttttggta ctgtaggtgt taagatactt tcaagtgatt
     4441 gtgttaaaaa aacttgcact cgtgcaacag caggagcatt gaaagttaaa gattctgttc
     4501 ttgaaacaac tacgaaaatt caagaaaatg tagaagatat tttagctgaa gcaaaagaaa
     4561 tcaacgagca agaagactta tctacatcta aggtaaacgt tgtacaagat actcttaaat
     4621 gcgaacaaga agttcttaaa actgaaacta taaaaactgt agaagatact aattctaata
     4681 gcattaaatg tgaagaaatc aaagataacg taattgaaga aaaaaatagt acttgtacaa
     4741 cagaataaat ttaatgatta ttatgattaa taatatcagg aggaagtaaa ttgaattttt
     4801 atataaaaca cgaaataaga ggtcgtatac gctttgactt acaacttggc aaattaaaca
     4861 acaagcagtc cgatactctc ttatattatt taacttctat aaatggtatt accaaagcaa
     4921 aagtttacga tagaactggt gatgcagtca tttattacac tggtgaaaga gaatacataa
     4981 taagagaaat cactaaattc agttttaaca atagcaaaat agaaaaccta gttcctgaac
     5041 ataccagcag ggaattaaac aattattata gagacaaatt agcaaataaa ctgctagtca
     5101 aaagtatctc caaaatattt tttccaaagt ccttaagatt ttttttaatt ggacttcatt
     5161 ctataaaata ttttaaaaaa ggtctctctt ccctgctaaa taaaaaaata gaagtttctg
     5221 ttttagatgc cactgctata ggtatttcta tttttagaaa agatatcaat acggctggtt
     5281 cagttatgtt tcttcttggt atcggtgaac tattagaaga atggactaga aaaaaatcta
     5341 tagacgactt ggctcaaagt atgtcactaa acattgaaaa agtatggtta agaaaaggtg
     5401 acactgaaat cttaattcca atttcagaga taaaggaagg agatttagta agtgtaacta
     5461 tgggaaatat gattccattg gatggagtta tagtatcagg agaaacaatg gtcaatcagg
     5521 catcacttac aggtgaatcc cttgccgtta acaaaaaaga aggctcttac atatatgctg
     5581 gaactgtaat agagcaaggc aatattgtta tgtgcgtcaa ggaaaaagct ggtactacta
     5641 gattccagaa aatagtaact atgattgagg aatctgaaaa actaaaatct tctgtagaga
     5701 gtaaatttga acatctagca gatacattag ttccatacag ctttttagga agtatattaa
     5761 cctatgcaat tactagaaac cctataaaat cactctctat attaatggta gatttctctt
     5821 gtgcattaaa actctctatc cctatttcag tactatcagc catgagagaa tgtaacaata
     5881 acaacattac tgtaaaaggt ggaaaattcc ttgaaggtgt tgcatgtgca gatactattg
     5941 tatttgataa gacaggcaca ttaacaaaag ctcaaccaac tgtttcagat ataattacat
     6001 tccaaaatta taataaggag gatatgttaa gacttgcagc ttgcttagaa gaacactttc
     6061 cacactccat agcaaatgca gtagtttacg aagctgaaaa acaagggctt agtcacaaag
     6121 aaatgcatac agaggtagaa tatattattg ctcatggcat ttcaacaaaa gttgatgata
     6181 aaaaggttgt aataggtagc aaacattttg tatttgaaga tgagaagtgt actatcccag
     6241 acggtgagga ggataagtac aacaatctat cagatgagta ttcacaccta tttatggcaa
     6301 tatcaggtaa attatcagca gttatttgca taaatgaccc tttacgaaaa gaagcaaaat
     6361 atgtaatttc aaatttaaga gaatgcggaa taaaaaagat tgtgatgatg actggagata
     6421 gcgaaaaaac agctaaatct atagcaagta aagttggtgt tgatgaatat tattcagaag
     6481 tcttaccaga agacaaagcc aattttgtta aaagtgaaaa actcaaaggt cgcaaagtaa
     6541 ttatgattgg tgatggaatc aatgattctc ctgctatttc agaatcagat gtcggaattg
     6601 caatgagtga aggtgctgaa atagcaagag agatttcaga tattaccata tcagcagata
     6661 atttgaataa tttaatcgtt ttaaagcaga ttagtaataa gcttatgaaa agagttgatt
     6721 taagttctaa gtttattatt ggctttaatt taggtctgat tttacttggt gtaggtggat
     6781 ttgttagacc aagtacatct gcctttttac acaacacatc tactgtcgga ataagtttaa
     6841 acagtatgac aaatttattg gaaaacacca atacttataa ctaccattaa tctccattac
     6901 ataaaacata tgatataaaa aatttataat tcatcttttt aaaagaatat gtcttaaaat
     6961 tagctttttt ctaatcaaaa ttatataaag catactttac aaattttaaa ctcaacttat
     7021 ttctattttt tacaaaaaag gagatgattc aaattttcat tttgaaacat ccccttttgt
     7081 aaatttcttt aaaatttata tattaattat attttcaacc aataattgta ttttcaacca
     7141 atctttcttc atagcatttt aaatcatttt gctttagata attaaattca gactctacat
     7201 aaataccaca gcctaccaat tcaattgtca aattaggtat attttccttt agtatactag
     7261 tctgctcata aataattctt tccaataaat caacttgtaa tatagaaaaa tgcttcataa
     7321 tctccccatc actatctata tctttcttga tttcatacca actctttgac aaaattccct
     7381 tcaaatcaat ataccctaga ctcctcaata tatctatact atcgctccat gcatacttac
     7441 taggtttatc aaagtatgat tctagtttct tcttctgctc atttgtaagt gaatcataag
     7501 aaagcttctt attaaaatgt gccttcaaag aaatcttagc catagaatat ggacttctac
     7561 cagagtttaa tcctgcattt ttgaactttt caattccttt atcttctact gaagaccata
     7621 ttgagtttat tgaatctgaa tcattgtatt taatatcaag accatgtgta atatttatat
     7681 agttttgtgg aaatacatat tgataataga catctttttt atcatcatat agagagaagt
     7741 atccactatc atataaatga atatgcacct ttacttttaa actatcctct aaaatatttc
     7801 gtctaaggtt cgggatattt gcatacatgg ttacatattt tatggcatca aagtttttat
     7861 ttaatggaac ttcaaaacta atttcatctc ctgtcaaaag ctttttcact tcttcttcat
     7921 tacaatcata tagagaatat gtattttcaa atcccacacg tgatttccca tctaaactgc
     7981 ctgttaatgc taccttcaaa atatggttat ctgttttttg ccattggtaa gcatcttggt
     8041 caagaaactc tctaatctgt ctattttgct ctttcgcctg atttataacc tcgttttcat
     8101 cttctgtaat ccctacatgg catctattta agatatttac tatattgctt ccaaatggga
     8161 atgtccatag ttgaaaagct gctgcctcaa cctgacacaa atatctaacc tgatttaatt
     8221 caatttgatg gataagtttt ttctgatatt cattcatctg attaccacta tctgacattt
     8281 gataaatcaa ttctcccatt gcaagattat cttttttctt atcaatctta tcagtaatga
     8341 taatttgagt ttccatcata tcctgtactt ttttaaatat tatagaaatc tcctctgagt
     8401 tttccatttt taagcttcca aacttcgtgc ttaattcagt taaaacttcc ttcatcttta
     8461 atttacttat ctcattttca aaaatatctt gatttttaac tgtactatcg aatttttcta
     8521 caaatggtat aacagattct ttcaaagttt tatctttaaa ttccaccatt tgagtattca
     8581 attcatctaa tttcttaata ttattttctt tatctttaat tgcctcttta actacctcta
     8641 ttttactctc aaaactagat tttacattaa gacaattatt aacaccacta atcgcagtat
     8701 ttataagaga acaagcagaa cttccaatac tcaatgcatt tttaatttta gatgtctttt
     8761 gctgtctttc aatagcttgt ttacttttct ctagtgcagc taacttatct ttttgctgtt
     8821 tattattgta atttgcctcc aacataccta tttctttttt ctggattttt gtgtaaattt
     8881 ccttatactc gctttcactt aacccctctt ttgctctttg aatatcgtca gctttgtctg
     8941 catagttatc atcatctata gacttaacta taatctcctt aatttggtca aatttagttc
     9001 ttctttcttc atcaacacct gccaaattat aagtcatttt atctaaagca ttttttctat
     9061 cttcacttag ctgttctcca agtacaaatc tcataccatc agaatccaat ttaaaatctg
     9121 aaaaatcaac catcctgtta gtccattggt attcctcttc tttagctgaa agattttcct
     9181 tcaaagattt tgcactgtca aatgccccta gacaagcttg accaacacca ctaaatgcag
     9241 tcagtaaact caatgcgctt tgtattccag aaagaattaa ctgtgttttc atttgttcct
     9301 caagttttgc ctgtttcttt tttagttcct ctatgtcttc ttgttcatct tctttcatct
     9361 ttataatttc ttgaatcaac aggttcattt ttgcattaac agaaagcatt ttattctcaa
     9421 gttcattttt taaaacctct atttgttgat ttccagattc aatttgagtt aggatacttt
     9481 ccttatatgt attgaaatat ccttctttta actcatcttt ctttccttgt tccaattctc
     9541 ttaaggtctt atccagatag tctgtcaaag aacgaatatc tgtaacacga tttcctccaa
     9601 tttcactttc ttcaatcatc tgcacataaa atgctgtctt ctgctcaagt gcaaataaaa
     9661 tcatactcca ttcgctaaaa ttctgatttt ttcctacaaa agattctatt ctatcagact
     9721 gcatcaattt atttataagg tattcataga tttcctttgc ctctttataa aattctttct
     9781 ttatattcat gtcatccata gaaagtactg ctttattttt cttctcaaaa ctatagtact
     9841 tctgaagtat ttctctattt aattgcatct ctattttctc aactgcataa aaaatttcat
     9901 aaatatgtga aaattctaaa atatcagctt ctaaaattcc tactgcacac aacagtctaa
     9961 gatttctata acctttaatt ccagaaaaac caaatctctc gaaaaattca tagaagaatg
    10021 tatctattga caaagaatac tcctgcttta acaattcctt ttcttttagt gcatctccag
    10081 agtgaccggc ttttccctct gctccggctg aacctgaatc ttcacgtttg ctaattgtcc
    10141 agtccttatg ttcttcataa agagtattta atttctctcc atcatctgct gcttgcttct
    10201 gatttaaagc atgattaaac acatatctat caaaataata gtagtttcta tcactattat
    10261 ccattggagg agaggtacct atatatctta ttgtttcttc atatatacct ctaattccac
    10321 caagacctcc tgcaccacca gctcctccag agcctccttt tcctgctaaa ccatgatttc
    10381 catctttttt acttatagca ctttttaata aaggagcttt tccaaggaga taaacctgtc
    10441 cagacttgct tccaagacct gcatttccac cattacctcc tgtgcctcca gttccacctt
    10501 gttttccttt ttctgctttt acaacatagt attttgtacc tttaacatta gcaaattctt
    10561 ttgactcttt tttagaacct attttagcat ttgccccagc ttctccagtt atccctgtat
    10621 ctcctttttt tccatcttgt ccatttccac cacgtccacc atctacgtaa agtttaagtt
    10681 ctcctctttt ttctatttct ttaaaagata atatgatatc acctgaagta cctgcattat
    10741 tgccatttct tccattcatt ccgtcgtaaa tagaactttc tccaaccaat ttttctgcat
    10801 ccttaccaga tacgttgatt gaataagtcc cttctggtat atgtaatttt tctgtaagta
    10861 gtacaatatt cttacctgag aagacttctt tctccatatt acagtcaatt ttcaactcac
    10921 aatctccata catatatata gatgacaaaa tattaagttg ataaccagat attattttag
    10981 tcaaatccga taaattcact ttaggtatag gaatatatat agaaagtaca ttttctttct
    11041 catatgattt tatatatgta caactttgaa tcttctctat cctatactct gcatcttcaa
    11101 gctttttggc ttcttcttcc ctatattctt cttctgctat ccaatatttg atatctttta
    11161 atgtatcttc taaagtattt tttagcaatg attttaacaa ctcacttaga ccaacaatat
    11221 gagtctcact acagtaacta tttaactcta aaagaagacg tgtttcttct aatatattca
    11281 ctttctgtac gccatcacca tatgaaagtt cttgtacaaa ctccataagc tctttcatat
    11341 tattagtcct actacataaa tctgtataca tcttatctaa ttgaatcttt ttatctttta
    11401 gactatttat agaagataga atggaaatag aatcttccat acctttttta acactttcta
    11461 tataaggaac taaaagtttt tctaggtctt tataggttac atcaacagct ttttgtattt
    11521 ctattttaca agaagctgta agcatcaatc ccaaatctgt tttttcaaat gtttcaggta
    11581 gatttttcat ttcatccaac aacttttctg gctgtttatc tagtggatta cataatttaa
    11641 tagatacacc atctgataat gctacattta ataagtacac taattcctta caaccgtcgt
    11701 aatctttctc ttgactatct aagtcttctt ttgctttttc caatatattt cttatttttt
    11761 cttctgttac attaccgatt agtgttttag gtattttatt aataagaaag aagaaatttt
    11821 ctttatactt tgcataatca ccaagcatat ctttcaaatt tttgcctgtt tctatcaata
    11881 atgtatgtct agagtccagt agggattgat agtctaagat aactaccatc cctttcacct
    11941 ttgaagatgt ggaaatagtt tcccttacaa gcatagcacc agcaatcata tactctgctc
    12001 cacggttgtc aaaaaaacct gggcaatcac ataatgaaaa atctctattt gcaatatcta
    12061 caacttctgg acataaagtc ttagaatata caccatttcc aatttcgaca gctgaatctt
    12121 ttgcagttat atatatttgt ccagtctctt catccgtttt ttcttccatc acacagcctt
    12181 ttaaataatt tatacaagta ctctttccaa cgcctgaagc acctaggaat aacaaaattg
    12241 acttttcttt taagtcatat tttctaagct cgtctcttcc ttcttccaaa aggtttacga
    12301 tttcactata aagtttattt gccatacatc catccctttc tatatttcgg aacaatagcc
    12361 ttgatatttt tctttaataa gattctcttc tacctttgaa acagctgttg ataacttagt
    12421 atttggagca ttaaatcctc cattgtctcc tctatctcca tattcagcgt attctcttgc
    12481 tggtcctgtt ttaccttcat tccagcttcc accactaaat tctatatgat atttaattat
    12541 actatctaac ttataatccc aacttgtaaa atatcctgta tagtatacag tcttatctat
    12601 accacttgga gaaaatgaaa gtgtattata tccgtgatag ccaccacttc ctccatatcc
    12661 acctaaacct ggtctaccat ttggacctgc ttctccatct ttcactgtta tatcacaatg
    12721 attaattatt ctattttttt gttcctctga atctgaaatg aagtaaatat tacctttctt
    12781 accagcattt ccacctcttc cagcatttcc accagctcca cctttttcac cttttttgcc
    12841 acttgtacct ttttcaaaat accctttaaa catctgtccg tggaaataac ttgtatatcc
    12901 tgcatcagct ccattacttc cagaagctcc tgtttcacca ttttctccat ctattccttt
    12961 agaaccattt cctccatttg caatcagtgt tagacgataa tttctaattt cttctttaat
    13021 atataagtaa atattacctg catctctacc atcttcacca tttttcccat acatagaatt
    13081 atctacaagt tctccgctct ttccacttac attaattttt acattactac ctacatcaag
    13141 attgttagaa gcaagaataa tatttttctc tgatgcaaag ttcattccaa ggttatcatc
    13201 catataaata gtatctttag caaagaacat aaaagtagaa acattgtcat ctacttttct
    13261 atttttgaaa tattccaata cactgctaat tactaagttt ggaattaatg ctcttatttc
    13321 aatacctttc ttatcattaa tattaattgt ttttactata aatggattta aaatgtattt
    13381 accaataaat tctctaatta tctcattacc ttcttctcca tatgcactta atcttgttat
    13441 actgtcttct aactcttcat tttgtgtaac tgtaacattt gtcaaaattg aattaaaatc
    13501 acttacacta tatacataat cctttttatt tgcaacttcc attaattttt ctctatttgg
    13561 taatgtaaat acctgttttt gcacttcata agaaactaaa actttttcta aattctttct
    13621 tattataatg aagttttgtt ccattatctt cttacttgcc ttttctataa taaattccat
    13681 atgtacagaa ggtaataaaa tttccccagt tccatgttct gtatatttac ttaaagcatc
    13741 aattatatct aagtttcctt ttatcttatt ttgtaatttc atgcaactat cttgtaagaa
    13801 taatccactt tgtttggcta atacgttgat aaaactctct atagtaagac ttgttgtact
    13861 ttccaaccag tttttaaata cttttacaac ctcatcatat tttgctattt cttgaatcat
    13921 tgttatactt ccaataatat tgataaaatc ttctgtatac gccttaacat aatcttctag
    13981 gctagatacg atattgtttt gaatttcttt tatcaacgta tctaaaacta atcttgcatc
    14041 tgcactaatt ggatattgga atgctgatgt cttatcttta acttcatcta attctagtac
    14101 ttgctttaat aagccttccc tctcatctga tgcaagtggc ttacaaagat gaatattttt
    14161 tccattatct tttagcaatt cttcaaataa ccaagctttt tcctctatat tactgtctaa
    14221 attttcgcat aattgttcat attttctttt tataacatta tatatttgtt tttctgttct
    14281 tcctaagaaa ctttttgaaa tgaaaaaagt tatactaccc ttaaaatttt ctttatgaag
    14341 acacatattt aactgttgga acaggtctag tacttttgta agtctagaat ctaatatatc
    14401 tgcttctggt atcaatacaa ttactgcaca tatagatgca gaatttttaa atacttcacc
    14461 taatgaaact gctgcactaa tatcatgggc tactccccta ttgtcgctaa aacctgcagt
    14521 atcacataat tttgcatcca ttccttctat tggttttctc atatttacaa tgttcgggta
    14581 taaagtttga gaaacagctc ctgaaccaat ctctgccaca gggtctaagc aatcaatata
    14641 tgatatacca gtatcttcat cttctacttc catcattaca catcctgcaa gatagttaat
    14701 tgcagtactt ttgccacatc ctgtcccacc aagaattaga attaaatttt gattttcagc
    14761 cttatttatt gctacttttc cttcatttaa taaaagtgtt atttcttcta aaagttgatt
    14821 gttattttct ggcatttatt ttcccccttg gttatatatt ttatttaaat aaagtttaat
    14881 cccttaagta gattgcaaag tttttagact atatttaaat ttgtttttta ttttttattt
    14941 ttaataaatt tgcattttca ctaaataatt attcttcttt gtttattaaa ataactgtgt
    15001 tgtataatat aatctttatc aacacagtta ttttatttaa tgcgcttatt ttattgtatt
    15061 ttatgtaata cagttgtttt ttatattata tgtccattat ttttctatgg ttattacata
    15121 tagattttta attatatttg taccattaat ttaaacattc ctatactact gcttaagttt
    15181 tacacctata ccagcttgaa tattttattt ttatttgctt aaatagttca actatactgg
    15241 tttaaatagg ttatctttat ttgcttaaat agttcaacta tactggttaa ataggttatc
    15301 tttatttgct taaatagttc aactatactg atttaaatag gttatcttta tttgcttaaa
    15361 taagttcaac tatactgatt taaataggtt tcctttagtt taaataattc acctatactg
    15421 gtttaaatag gtttccttta gtttaaataa ttcacctata cctacttgaa tagttcactt
    15481 ttatttgctt aaattctata ccaatactgg cttaaacatt atactaccat gattgtattg
    15541 tctatcttca actacaataa aaacaggttc taaatcttta gtagatgtta tttttaattc
    15601 taaaaaaata ttatcagttg gtaatatttt tacatcataa ttatttaaat tattattcgt
    15661 gatactatta aatacatcac cttgacgttc aaaaaaaaca ttatcaacta ttacaaaata
    15721 aacatcttct tttctactat tttcaacctc tatagtattt tgtttagtta tatttagtct
    15781 catcttccac ctcctattaa tattacttaa ttatattaat acttgtaatt gttgcattat
    15841 gttcatcaca aggaagaggt ttaaaaacaa ctatctctgc taaataattc tgtggaggat
    15901 ttgtaactga agtagcattg caaataaatt taaaatttgt tcctgctaca acttgagtag
    15961 aaacaataag tggttcataa ccaacccctt ctaacattcc tacagcttca ttaaatactt
    16021 ttaaatcttc ttcttcgaca gctctgaatt ttgaccatcc accaacaaaa agactcatat
    16081 aaaaacctcc tttatatata tatttattta tatatagtag taccaatttt ctcaatattc
    16141 aatattttct gtgtaactgg tcaatgaaaa tgcataactg gataaaaata cttataaaat
    16201 aacttaactt tacatataaa tagcttactt tacatgtaat aagattattc tacatgtaat
    16261 aagattattc tacaatatga aatgcatctt gttttgaata tattctaaat acaataatgg
    16321 atattttcaa ttattataat tagaaaatat ccattactta acttgtttta tttaaaatca
    16381 catagagact ttattatttt ttttattgca tgaatagcta tttcaggtat cataaggtga
    16441 tataccccct ccttgaaacc acaaaaaaca tgacaaactt tacgaatctt gtcttaaaaa
    16501 actacaggta cattccttat ttgtggattg gagtagccat aacaagcaaa ttttacaatt
    16561 tttatgatga caaaaatcaa taaaatcgct tagtatataa cacgaaatac tacttgttac
    16621 tattaagaat agttagatag gaagtatgca ttatacaaat aaaggaatca ataaagaaag
    16681 ttaaaacatc cctacaaatt aaaaatctgt tacatttttc tatatttaaa cgttatttac
    16741 ttacaattgg agaaataaca ggttttcctt ctcggtcaag taaaggcgta aatccggctg
    16801 cattgccata atagtggaat acatagttca cacctgtttc tttatccacc caaatctccg
    16861 ttgcatttat tttcccttgt gaatatactt tttcaaatct atcttttccc attttataat
    16921 cctccatatt tttgattggt ctatgccttc ttcacttaag tagaaaaaat acataactta
    16981 tttttttaat tctaatatga gcacgtaaaa atgtcaaaca gcttatttaa tttcataact
    17041 tcatgttact gttcgtaacc ttgtctgttt acttacactg cattacagca ccattttatc
    17101 ctttacatta ttgtattgca cacagtaaaa atgcttactt tatgggattt ttcaactaaa
    17161 aaaaggattt tatctccaca aaacatttac tatttgttac aatataccta attttaatct
    17221 catatcaaca tttaatgaag atataacctt tttcaaatat tgtaaagact ccttaaaaat
    17281 attagaaaaa gattctgcaa atctctcaac atctcctttt tttaaatacc taagtatctc
    17341 aaaacataca tcaaaacgtg ttttcaaaat ttcattatat tcttcatgaa aaaatctctc
    17401 taaatagatt ccaaatatca tatattgttt taaatgcaaa aatgtttcct gtaatacata
    17461 aatttgtgta taatctacta tcttacaaag taaaacaaaa tctggataaa ccttacactc
    17521 ttcacaatta ttttgtaagt accttaaatg agtttctatt ttatctacag ctatcaaatc
    17581 cattttattt cctagtaaaa gtactacatc ctcaagagta atcgtaacaa actccatagc
    17641 atccaaaagc aaactcaacc ttttagctcc ttcttctgta tttatataat catcatcata
    17701 ttcagaaaaa agcgttacat atgttccctt gccattaatt gttttagcaa ttcccaattc
    17761 atttagctca ttataggcac ttctaactgt tggaagtgat acattatatc tattaattat
    17821 cgaagtaatt gatggtagac aatctcctat tttaatattg ccttcaaaaa tttgacaaat
    17881 tacatctgaa acaattaagt catataaata acatttttcc aacgttacag aattaaaact
    17941 acttgtatct atactttgtg gagcacgatt ttctaccatt ttaagtatgg attctctaca
    18001 agctttatac atatatgtta atagtttttt aaattcaatt agattcccat ccaatccata
    18061 taagtaagtt tttcttacct gctctatgta tttattacga aaaaagtcta tacaacaatt
    18121 atccaagtta tccaagttat cgaaattata ggccaattgt gaaataatga catcatgctg
    18181 aataatctca caaaaatggt gaatcaggaa attatttgtt ttacttatta gtttatttat
    18241 atattttagc ctttgttctt taaagactaa ataattagaa ctattttttt ccatacaatc
    18301 gataatctcg tttaattctt caaagtcttt agatgtaaat cttttaatat tgtacatagc
    18361 aatagaagga aatattaaac taaaaatctt atatatttct gatatttgta aaatcttctc
    18421 atataataag tcagattcta ttgattgttt actcgtactc tggattaaaa ctggtctaga
    18481 accagctttt gtctctataa agcccttttc tgagagcatt tttattacag tttttatagt
    18541 attttttgat accatatatt cttctgacat gctttttata gaatcaagcc tatctccaat
    18601 agtaatttta ccagtataaa tttgttgaat tatatgctca aaaataatta aatattgtgg
    18661 ttttctcttc atatttttcc tcttcgataa attagattta ttgttttttg taaggtatat
    18721 ttacttttat ttaatagggc aaaatagttg cttatttttt cctcataatc tataattaat
    18781 ataaaccatt tatatatatg gtctaagttt tataatactg taatgcagta aaatagcatg
    18841 ttgtagctat actacagcaa attaacatac cattgtagta tattaattgg aataatttta
    18901 agtacttcaa aattccagca aaacatatat gtgtttttga tattatgtat attcgttaat
    18961 agaatagcta tacttgtttt acataataaa ttatatgata cttgctatat gtaatcacta
    19021 tatttaatac acataactat tatacttgct atatgtaatt ac
//
LOCUS       DAYAKB010000070        18862 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.070, whole genome shotgun sequence.
ACCESSION   DAYAKB010000070 DAYAKB010000000
VERSION     DAYAKB010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18862
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.070"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            211..3756
                     /locus_tag="ACGI3L_002869"
     CDS             211..3756
                     /locus_tag="ACGI3L_002869"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9198566.1"
                     /translation="MNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHTY
                     LSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRMT
                     ISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKSG
                     KIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQLF
                     DKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKIV
                     SIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGGV
                     KTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQLE
                     KQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSKR
                     FEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFKD
                     DRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVDI
                     TSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENAT
                     KNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDNN
                     GKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKGA
                     LMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDIS
                     ETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALYS
                     AKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIEV
                     AVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLGN
                     YLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSYN
                     RMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTYE
                     LLFINKKILESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKFE
                     VQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            3941..5875
                     /locus_tag="ACGI3L_002870"
     CDS             3941..5875
                     /locus_tag="ACGI3L_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HFG9198567.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5981..6976
                     /locus_tag="ACGI3L_002871"
     CDS             5981..6976
                     /locus_tag="ACGI3L_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MqnA/MqnD/SBP family protein"
                     /protein_id="HFG9198568.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6948..7733
                     /locus_tag="ACGI3L_002872"
     CDS             6948..7733
                     /locus_tag="ACGI3L_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198569.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7721..8419
                     /locus_tag="ACGI3L_002873"
     CDS             7721..8419
                     /locus_tag="ACGI3L_002873"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198570.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8542..9015
                     /gene="ybaK"
                     /locus_tag="ACGI3L_002874"
     CDS             8542..9015
                     /gene="ybaK"
                     /locus_tag="ACGI3L_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFG9198571.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKFYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9212..10051
                     /locus_tag="ACGI3L_002875"
     CDS             9212..10051
                     /locus_tag="ACGI3L_002875"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HFG9198572.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKN
                     VVI"
     gene            10064..10612
                     /locus_tag="ACGI3L_002876"
     CDS             10064..10612
                     /locus_tag="ACGI3L_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HFG9198573.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10678..11859
                     /locus_tag="ACGI3L_002877"
     CDS             10678..11859
                     /locus_tag="ACGI3L_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HFG9198574.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEIKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12238..12540
                     /locus_tag="ACGI3L_002878"
     CDS             12238..12540
                     /locus_tag="ACGI3L_002878"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9198575.1"
                     /translation="MDKTQTALSKTLNITAYDDKVLVGCLRVLSDGYYFGTITELLVL
                     PEYQKQGIGSKLFQLAKENTPTMLYFGAQPGVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12690..12953
                     /locus_tag="ACGI3L_002879"
     CDS             12690..12953
                     /locus_tag="ACGI3L_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9198576.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13082..13924)
                     /locus_tag="ACGI3L_002880"
     CDS             complement(13082..13924)
                     /locus_tag="ACGI3L_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1-like domain-containing RNA-binding protein"
                     /protein_id="HFG9198577.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14219..14953
                     /locus_tag="ACGI3L_002881"
     CDS             14219..14953
                     /locus_tag="ACGI3L_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198578.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            14963..16096
                     /gene="nagA"
                     /locus_tag="ACGI3L_002882"
     CDS             14963..16096
                     /gene="nagA"
                     /locus_tag="ACGI3L_002882"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFG9198579.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16195..16944
                     /gene="nagB"
                     /locus_tag="ACGI3L_002883"
     CDS             16195..16944
                     /gene="nagB"
                     /locus_tag="ACGI3L_002883"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFG9198580.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17119..17391
                     /locus_tag="ACGI3L_002884"
     CDS             17119..17391
                     /locus_tag="ACGI3L_002884"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198581.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18051..18755
                     /locus_tag="ACGI3L_002885"
     CDS             18051..18755
                     /locus_tag="ACGI3L_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198582.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
BASE COUNT         7574 a         1971 c         3311 g         6006 t
ORIGIN      
        1 ataaagttat aatttttaat attaattaag aatgatgaaa tatgaataaa gattttacaa
       61 ataaatctta agctatctta tttaattcta atacaggaag aaggtaaatg tatattgaaa
      121 aaatcataga aatagaagta aacaatttaa ataaatacaa aggtttgcaa aagaagtaat
      181 ataattatat acaatgagga tgtgagtatg atgaacagac taaagccaag aattttaggt
      241 attagtatct tgtttattat tataattatt ttaacatgtg gagctgtttt caagtttaaa
      301 tttaaattag ataataaatt aaaagaaacc acacatacat atttgtctga gtttacagaa
      361 cacaatataa ttaatctcaa gacaagactt agtggtcaat ttgacatgct tgaatctatt
      421 gctaacttca taggaaactt gaataatata aatgatgaaa tggtgattga tttaatggat
      481 tctgatgtaa agcgaagttc tttaattaga atgactatct ctacattaga tggggaatgt
      541 tattctaatg atggaattac ccataatgtt caagatagag attattttaa aaaagctaaa
      601 aatggagaaa agaatatatc agagccttta aaatctattg ttaataataa agaaataata
      661 gttttatcta ccccagttta taaaagtggg aaaatagttg gtgttttaag tggaatttat
      721 gattcaaaaa agttaaatga gttattagga ttatctgcat ttgatgaaaa agcagatgtt
      781 tttgttgcaa agaaaaatgg agatatagtt gctcaaaaaa caaataaaaa tagaaagacg
      841 ctatcatgta tatttcagct ttttgacaaa gataattgtg atgaagatga ttgtctaaaa
      901 actataaaag aaaatatgaa aaatgataag tctggatatt ttaattataa cttagataat
      961 gaaaaattta tgttaaacta tcagccactt ggagttaatg attggtatgt tttttctgtt
     1021 gtgccaaata aaatagtatc tattcagtca gagaatatat cttatgatgt atatattttt
     1081 gcattagaaa tactactagt tatattgatt tttataatat atatagcatg tattataaat
     1141 aataacacca aaattattat aaatgaaaaa gaaaaattta aagtactcac tgataatata
     1201 ttaggagggg ttaaaacctg tttaaaagat gaatatatga ctatgacata tgtaagtcag
     1261 gggtttttag agcttacagg ttactcttgt gaagatttaa ataaaatatt taaaaataga
     1321 tttaaagaca tgatttataa agatgattta gacaagttta attgtattat tctaaatcaa
     1381 ttagaaaaac aagataaaat tgaagttgaa tatagaattg taagaaaaga tggaagtata
     1441 atttggattt tggagagaag taagtctata aatgataata aaggaagtga gtgtattcag
     1501 ggagttttaa ctgatataac agaacttaag aaaatacaag aagaattaga ttcaaaaaga
     1561 tttgaaatac aggctatcaa tgatagtatt gttggtggaa tagtgataac tgagataaat
     1621 gatgattttg atagtatata tttaaatgaa ggttatttaa atatgattgg atatacacgc
     1681 aaacaactgg aagatgagct aaataataaa ttaatcaaac ttatttttaa agatgataga
     1741 acagaattaa ttaatagtat aaacaaacaa ctcaaattaa gtgatacatt tgcatctgaa
     1801 caaagagttg aaaaaaggga tggcactatt atatggattt tattaaaagg aagaaagatg
     1861 atttatgata atggaaaatc tgtactttgt tgtgttattg tagatattac ttctgctaaa
     1921 ttattagagc aagaacttaa aaagagtgaa gaacgtcatg aaatcattct aaagcagacg
     1981 caaaatatta taatagaatg ggatatagaa aaagataaaa tgaatatatc acctaattgg
     2041 tataataagt ttaaatatga ccctataact gaaaacgcaa caaaaaatat aattaaatca
     2101 gtagatatat atcatgatga tatggataag tttatttcat taattaaact tacttcacaa
     2161 ggtagtgagt atgaagagtg tgaaattaga cttagaacta gagatactat ttacgcttgg
     2221 tttagtataa aggcaacaac tttatttgat aataatggta aaccttataa agtagtagga
     2281 agtttgactg atattgatga atcaaaacga gaagctgaaa agttgaaaga aagggcagaa
     2341 aaagaccctc ttacagatct gtataataaa aaagcatcac aatcacttat agaggagtac
     2401 ataacattgg ataaaaaaag aaaaggtgct ttaatgatta ttgatattga tgactttaaa
     2461 ggaataaatg ataatttagg acatttatat ggggatgctg tattaagtga aattgcaaat
     2521 gacctaataa atctatttag agcaaccgat atagtaggca gaattggtgg agatgagttt
     2581 attgtattta taaaagatat ttctgaaaca agagatatta taaataaagc agaagaattg
     2641 gtaaaaacat ttgaaaggtc ttttttaggt aaaggacgaa attataaaat atcattaagt
     2701 gtaggaattg ctaagtttcc acaagatggt atggactata tgacactatt tagaaatgcg
     2761 gatatagctc tttactcagc caaagggaag ggcaagaatt gttatacatt gtatgataaa
     2821 aaatttgata aagtccaata tataactaat acaagaaatg caggagatag tgataatgta
     2881 gagatgtctt ttaaagaaca tatcacaaat tatatatttg atatactata tgaatcaagt
     2941 gatatagaag tggcagtaaa tttaattcta agtattgtag gtaaacactt taatgtgagt
     3001 cgcatgtata tatttgaaaa ttcagatgat aatcgagtat gtaaaaatac atttgaatgg
     3061 tgtaacgaag gtgtaacctc ggaaattaat aatcttaaaa atatttgtta caaggattta
     3121 ggcaactatc ttttaaattt taatgcagat gggttatttt attgtaatga tattgaaaat
     3181 ttaggtagtg atgtgaaaaa agtacttaag ccacaaggca tacgttcaat attacaatgt
     3241 aaaattttag agggtaatga atttagaggg ttcataggat ttgatgaatg ttcatataat
     3301 cgtatgtgga ctaatgatga agtgaacact ttgacattta tatctaaaac gctcagtatg
     3361 tttttattaa aaatgcgtat tcagagtaag ctagaagagt ctttaacaat tcaaaaatct
     3421 gtgatggata atatggatat atgggcatat gttgttgaca ggaataccta tgaattacta
     3481 tttatcaata aaaaaattct tgagtcagca ccaaacactc atgtaggtga tttatgttat
     3541 aaagcgatat ggaataatca agataaacct tgtaaaaaat gccctatgat atatttaaaa
     3601 gatggtgatg atacttataa atcattcatg cataataaaa agtttgaggt acaggcaaat
     3661 ataactacaa ctactttgaa atggtttgat ggtaaagatg catgtttaat atttggaagt
     3721 gaaataacta gtattgaagc tgaagaaaat acttaaaata ctgtgttata tatatactta
     3781 aaatcgcaat ttgaatttat tagacttaaa atgtctatat aaatcattta agttgtggtt
     3841 ttaagtattt tttatgatat aattaagcgt taagaacaaa attaaaagat acttttgtat
     3901 aaaaaaatat ttgttaaata tatattgagc aggtgataat atggaaaata agtttttacc
     3961 aataagcaaa caagatatga tagatagagg atgggaagaa ttagattttg ttctagttac
     4021 aggagatgct tatgtggacc atcatagttt tggaacagca ataatatcta gagttttaga
     4081 aagtgctggg tataaagttg gaataatagc tcaaccagac tggagaacta cagatgattt
     4141 tatgaagcta ggaaaaccta gacttgcatt tctagttaat gcaggaaata tggattcaat
     4201 ggtcaatcat tattctgtaa gtaaaaagca tagagaaaag gatatgtatt ctccaggtgg
     4261 gaaaatgggt tatagaccag atagagctac tatagtatat tgcaataaaa taagagaagc
     4321 atacagtgat gttgcaatag taataggtgg aattgaagcg agcttaagaa gatttgcaca
     4381 ctatgattat tggagtgata aggttagaaa gtctatgtta atagatagtg gagcagattt
     4441 attagtttat ggtatgagtg aaaagcagat tgtagaagta gccaatgcac ttaatgatgg
     4501 atatgaccca aaatacatta gacatattga tgggacatgc tatatttcag atacattgga
     4561 agaaatatat gataaatata tattaattcc atcatataaa gaaatttgtg aagataaaat
     4621 gaagtatgta gaagctttta aaattcaata tgatgagcaa gacccattta gaggtaatat
     4681 aattgttcaa cctcatggaa gtaagtatct ggttcaaaat aagccagaaa aaccacttag
     4741 tagagaagaa ttagatgaag tatatggatt accatatcag aagacatacc atcctgtata
     4801 tgaaaaattt ggaggaatac cagctataga agaagtaaaa tttagtatag taagttcaag
     4861 aggctgtttt ggtagttgtt cattttgtgc aataacattt catcaaggta gagcagtgca
     4921 aagtagaagt gaaaaatcaa ttattgatga agcaatagga ataacaaatt tagatgattt
     4981 taaagggtat atacatgatg ttggaggtcc aacagctaat tttagaagac cagcatgtaa
     5041 aaaacaaatt actaaaggtg cttgtaaaaa tagacaatgc ttatctccat caccatgtaa
     5101 aaatttagat gcagaccaca gtgaatactt acatttactt agagctgtaa gaaaattacc
     5161 taaaataaaa aaggtgtttg tgcgttctgg aattagatac gattatgtaa tggcagataa
     5221 gaacaataaa tttcttagag agttgataga gcatcatgta agtggtcagt taaaggtagc
     5281 cccagaacat atatcagaag aagttttaaa gtatatgcaa aaaccagcag gaaaaactta
     5341 tgataaattt agacagaagt tttttgctat aaatgaagaa ttaggtaaaa agcaatattt
     5401 gataccctat ttaatgtcta gtcaccctgg ttctacctta aatagcgcta tagagttagc
     5461 agagtattta agagatactc actaccaacc agagcaggtt caggattttt atccaactcc
     5521 agggactcta tctacaacca tgttttatac aggtattgac ccgcttacaa tgaagccagt
     5581 ttatgttcct aaatcaaaac gtgacaaggc aatgcaaagg gctttattac aatatagagc
     5641 acctagaaat tatgatttgg tatactctgc gttagttgaa gcaggaagag aagacttaat
     5701 tggttttgga catagatgtc ttataaagcc aaaaaatgaa aagccttatt ttaatagaaa
     5761 taattctaaa aaaaatgtat ctaaaggaac aaataaaaac aaaaaaacta atacaaataa
     5821 cagaagtaat aaaaatcaac aaaaaagttc aactaaaaaa aagaaaaaac attaaagtat
     5881 aaataaaaat acttaaaaaa gaaggattat tcgataaatt aacagaaatt agtataaata
     5941 aatataatta ttttaatgac gttacctttg ggaggaagag atgaaaaagt atatttctat
     6001 aatattatta gtggtgttga ctatggttgt tttggtagga tgttcaccag gaaaagataa
     6061 ccctaaaaat aaggagctat cagttgtcaa acaagtaaaa gtagctgttc cagatggact
     6121 accagcagtg gcaatagcta aacttgcaaa tgaaaatcca gagattaaag aaggatatga
     6181 aacagtgtat agcattgaaa agacacctga agcgatttcc actagagtga tgaaaaaaga
     6241 tgcagatata gctatagttc cttcaaacat ggctgcaata gcgtataata aaacttcatc
     6301 atataatatt gttggaactg taggaatggg ttcactttat ttggtgtcaa cagaaaatat
     6361 aaaagattac tctgatttag ttggtaaaga agttggatgt actggaaaag gacttactcc
     6421 agacataact ataaaaagtc ttttgttaca aaaggatata aattattcag atataaaatt
     6481 taattatgta aattcagcaa gtgaactggt accattattg gctactggta aagttaaaac
     6541 aggtattgtt ccagaacctg cacttagtgc tttgatgtct aaaaatccag acataaaaat
     6601 tataaaaagt ttaaatgact catggaagga agtaagtggt tcaaaagatg gttatcctca
     6661 atctacttta attgtaaagt ctgaattttt aagagataat aaagattttg ttgattcttt
     6721 tgtaggtcaa ttatcaaata gtatagattg ggcaaacaaa aatcctgaag aattaggtgc
     6781 atattctgaa aaaataaaaa tatctactga atcaaagata ataggaaaat ctcttgaaag
     6841 agctaatttg aaatatattc cagttaagga catgattaaa gattataaaa attactatga
     6901 gaaattagct aattttgatg ataagacatt aggaggcaaa gtaccagatg aagcaatata
     6961 ctttgttgag aaataaaaaa aataaagaac aatttataga taaaatggag gtaacacttt
     7021 cttgtgttat cctcttattt ttatggcaaa ttattgcttt aaaaattgat aatgatattt
     7081 ttttaccaac agtaggtcaa gtgtttaata gtataaaaga gattatgcta aattctagtt
     7141 tctatataga tatactttac tctatgggga gatgtttttt tagtttttta ctggctatga
     7201 tttttgctat tatactttca atagtgtctt atttaaatag attttttaga aacttattaa
     7261 agccaatcaa tgctttgaca cgttcaatac caactatgat attggtagta cttgcactta
     7321 tttggtttga aaaggatagt acccctttta tagttggatt tactatagtt tttcctatat
     7381 tgtatgataa cgttttgggc gctatattga atatagacaa gaacttatta gaaatggcta
     7441 atgtgtataa aataaggttt atagataagg tgttaaaaat ttatttacca gccataaaat
     7501 ttcaaattat atctatacta gtatcaacat tttctttaag tttgaaagtt gctatagcag
     7561 gagaggtgta tagtcaacct acatatggta ttggaactat gatacagact gaaaaaatta
     7621 actttaacac atctggaata tttgcatgga taattattgt tcttttaata tctgctattt
     7681 tacaaatagc tcaaaagttt ttagcaagga gagctttttt atggaaaaga taaagttgag
     7741 tattgaaaat ataaataaaa gatatgatag tcgtattata tttagagatt ttaatattga
     7801 tttttatgta aatgaggtaa attgtatcct tggaaaatct ggttgtggaa aaactacact
     7861 cttgaacata ataagtggga ttattaaaaa tgacaccaac aatctaaata tcaaagaaaa
     7921 tttaaataga gtaggaaata agcttgaagc tagttacata tttcaagatg atagacttat
     7981 agactggtta acagtagaag aaaatataaa gatagttgta aataaatact ataataaaac
     8041 tcaattaaat aaaatttgtg atgaatactt ggaattggtt ggaattagtg attataaaaa
     8101 attctatcct caaatgctta gtggaggtat tagacaaaga gtaaatattg ctagagcttt
     8161 tatatatcca tcaaaaaaca ttataatgga tgaacctttt aaatctattg atgcaaagaa
     8221 tacacagctt ataatggata attttagaaa tatattaaga aaagaaaaga gaactgtgtt
     8281 atttgtaact cataatattg aggaagcatt gtttttagca gataggatat ttattttagg
     8341 agactctcca attagaataa aaaaaatatt aaaaaattct aaggaattgg aaaaaaatga
     8401 agttttgaag ttgatataga gttataataa tactgtcgtt ttaaaatata tttggttaaa
     8461 atctataaga ctatattaaa atagtacaga atattcaaaa ctgtgtataa tgttcgtatt
     8521 ttataaaaag gaagtgaatg tatggttaag actaatgcta tgagaatatt agattcaaat
     8581 aagattgatt ataaagtaat gtcttatgaa gtgaaaagtg aacatgtgga tggtgttgag
     8641 gtggcacatg atataggaag agatgtaaat gaagtgtata agacattagt aactcaagga
     8701 gttagtaaga atatatatgt atatgtaata ccagtacatg aaaacttaga cttaaaaaag
     8761 gctgcaaaag tagctaaaga gaaaagtgta gagatgattc atgtaaaaga tataaataag
     8821 cttacaggtt atattagagg cggatgttct cctataggta tgaaaaagtt ttataaaact
     8881 tttgtaaatg aaagtgcaaa gaatttagat acaattattg tgagtgcagg aaaaatagga
     8941 tatcaaatag aactatctcc atttgattta caaagactta taaaagtaga atttgtagat
     9001 gtaataaaaa aataagaatt acatataaaa tatagagctt atattctcaa taataggtgt
     9061 tgtaatatta ataaaatgaa taagaatttt aaaataaata ttcagttact tatgtgtaat
     9121 tggtataaaa atattgagaa attttaaaaa caatggtaaa gtgtaagtat aatcacgaat
     9181 attttttata aagtaatgga gggatgttcg cttgagaaaa ataaaatctg aacaaatcgt
     9241 cgagcaggta aaaaaacttt gtatagaagc gagcctatat ttaggagaag atgttttaag
     9301 ttgtataaaa gaaaaagcga aaagcgaaaa gagtgaagtt ggaaaaaata tattgaatat
     9361 attagttgaa aatgctgaaa tagctaaaga aaaaaatata ccaatatgcc aagatactgg
     9421 tatggctgta ttttttgttg aaataggaca agaagtttta attgaaggag acacacttac
     9481 tgatgctata aatgagggag taagacaagg gtatgaagaa ggctacttaa gaaaatctgt
     9541 tgtaagtcca attaacagag taaatacaaa agataataca cctgctgtta ttcattatga
     9601 tatggtaaaa ggtgataaaa ttaaaataga atttgcagct aagggatttg gaagcgaaaa
     9661 tatgagtaag atgaaaatgt taaagccatc agatggattg gaaggaatta aaaaattcat
     9721 aatagataca gtttcagaag ctggacctaa cccatgccct cctatggtaa ttggagttgg
     9781 tataggtggg actgtggaca aatgtgctca aatagctaaa aaggcacttt ttagagaact
     9841 aggtgaattt aataaggacg aaaatatagc aaaacttgaa agtgaactat taacagctat
     9901 taataaactt ggtataggac ctcaaggctt aggtggtact acaacagctt tgggattaaa
     9961 catagagact tttcctacac acatagcagg tctacctgtt gttgtaaata taaactgcca
    10021 tgcatcaaga cataagaatg tagtaattta ggaggaaaat aaaatgataa aaataactac
    10081 acctgtaaat gaaattgata tagcaaaatt aaattgtgga gatacaatta gtttgagtgg
    10141 tatactttat acagcaagag atgctgctca taaaagattg atagattgta taaataaagg
    10201 tgaagaatta ccatttgacg tatatggtca aggaatatat tatgtaggac ctactcctac
    10261 aaagccagga gaagttatag gtgctgcagg tccaacgacg agttatagaa tggatgattt
    10321 gactatacct cttttagaaa gaggtcttag attgatgata ggcaagggaa aaagaagtga
    10381 tgaagttata gaaggtatgc aaaaatacgg agcagtttat cttgctgcaa taggaggagc
    10441 tggagcgtat atttcaaatt caataaaatc atgtgaaatt attgcatatg aagatttagg
    10501 agctgaagct ataagaaaga ttgtagtaga agaccttaag cttacagtag caatagatag
    10561 ctatggaaat aatatatatg agcaaggtcg agcaatttat gaatgtaaat aatgtttaga
    10621 aataaatatg aatatcaaaa ttaaaaatag ttgtgtatat tttaaggagg aaaattgatg
    10681 tctaaggatt atgcaaaatt ggcattagaa atgcatgaaa tcaacaaagg gaaagtaagt
    10741 gtagaaagca aggtagaaat taaaactaag gatgatttat caacagcata tacaccaggg
    10801 gttgctgaac cttgtttaaa aatacatgaa aatcaagatg atgtttatag atacacttct
    10861 aaagggaatc tagtagcagt agttagtgat ggaagtgctg tacttggatt aggtaacatt
    10921 ggtgctgaag catctatacc tgttatggaa ggtaaagcta tattatttaa acaatttgca
    10981 gatgtagacg cttttccaat atgtttaaag actaatgatg tagatgagat agttaaatct
    11041 gtagagttga tggagcctgt atttggaggt ataaatttgg aagacatatc ttctccaaga
    11101 tgttttgaga tagaagagag attaaaaaaa tctttaagta tacctgtttt tcatgatgac
    11161 caacatggga cagcaataat agttgcagcc gccataataa actcaataaa gttaattgaa
    11221 aataaaaaaa tagaagattt agaaatagtt ataaacggag caggagctgc tggtatagcc
    11281 atagcaaaga tactacttaa tatgaatgtt aaaaatataa tcttatgtga tagaagtgga
    11341 gcattggaag ctagtataga aaatctaaac tatgttcaaa aagaaatgtt aaaagtaaca
    11401 aatataagaa atgaaaaagg acctttaaaa gatattataa aaggaaaaga tgtatttatt
    11461 ggtgtttcag gtccaggagc tgttacaaag gaaatggttg aaagtatgtc tgagaagcca
    11521 ataatattgg caatggcaaa tcctactcca gagataatgc cagaagaagc aaaattaggt
    11581 ggagcattta taatgggaac aggtcgttca gacttcccta atcaagtcaa taatgtactg
    11641 gcttttcctg gaatatttag aggtgcactt gatgttaagg ctaaagagat aaatgaagaa
    11701 atgaagatag ctgctgcata tgcaattgct aatacaataa gtgatgaaga aatatgccca
    11761 gagtatatat taccagatgt atttaataag aatgtagtaa aaaatgttgc taaggcagtt
    11821 aaagaagcag cgataaaaac taaagtaaat agaatataaa tttttatatg ttcatatatc
    11881 cttatattat cgggtatatg ggcattttta ttataggttt atactcatat atccttactt
    11941 ttatatacat atctttatga ttaaaggtgt tagaaaatgt agtaaatttt atactatcag
    12001 actctatctt tattacttta gtagatacat ggttgtaaag gtttatagaa aaaaatatag
    12061 gaaggcagat ttttattgtt gcgtatatat gagaatgata taatatgaat attataaatt
    12121 aataaattta aatttatgga ggtacaagag atgatggaat ataaagttaa tgaccaagaa
    12181 cttaatgctt caatgtttat cccattcgtc aacaggatat ggccaggaga ttatgatatg
    12241 gataaaacac agactgcatt atcaaaaact ttgaatataa ctgcttatga tgataaagtg
    12301 cttgtaggat gtctgcgagt tctttcagat ggttattatt ttggaacaat tacagaattg
    12361 cttgttcttc cagagtatca gaaacaaggc attggtagta agcttttcca gcttgctaaa
    12421 gagaacaccc caactatgct atattttggt gcacagccag gagtagaagc gttctatgaa
    12481 aaaaatgggt gccaaagaag tctgcaatcc tacataataa aaaagaaaga tagttattaa
    12541 agttccagct ttcaataatc ttaaaagtac aatattttag tggaatcatt tcatttttta
    12601 ttactaatat gacataaaca tgtcatatta gtattgatat acttttaata tggttaagag
    12661 ccaaagaaaa atataaggag tgatttaaaa tggaagaaac taaattttgc caatgctgtg
    12721 caatgccaat gggacaaact gatgaattat atgggacaaa taaagatgga agtaaaagta
    12781 ctgattattg tagttattgt tttaaagatg gtgagtttac agctgatata agtatggaag
    12841 agatgataga agtttgtatc cctcatatgc ttcaaagtaa taaggatatg actgaagatg
    12901 aagcaagaac aatgatgaac aatttctttc caacattaaa acgctggaaa taattttatg
    12961 caaaattagt tatatgcaaa acatgaaata tggtgttgag aataaggggt ggtgtgcttt
    13021 atagcatacc acctgttttg ttacttggag ttcagttatt ttcctaaata ttttaaatat
    13081 actattttag ataagttccc tcttcatctt gataaattaa tccttttttc ataagcactc
    13141 caagagctcg tttaaaattt ttcttacttg aattaaataa tatagaaata tctttagggt
    13201 cagatttatc attaaatctc atatatccat cagaaccttc taaataactt aaaatcttat
    13261 tttctaaagt atcaagttca tcctttctat ttcctctagg agaaagacca agttttccat
    13321 cttcatatat ttttatgaca tgtaaatttt caagaacatc accagttttt agttcagtaa
    13381 agtactcatt atgaagtatt acaccagcat atttattgtc tacacatatc attgcagaat
    13441 tattagtttg gaatccatat acaactccag ttacaatatc tcctacattg taagtatggt
    13501 ctgttaataa gtatgaatct atgtctgtag tagcagcaat tcttttgctt ttgtctaaat
    13561 atatataaaa taaatatttt tcgtctctaa atagtggata agtcttagct ttaaaaggaa
    13621 ctaatatgtc tttaggaagt cccatatcta taaaagtacc aatgtctgta ttatcaacta
    13681 cttttaaatg tgctacatcc ccaaccttag ctaaaggcgg tattaaagtt gcagcagttc
    13741 tgtcatcaga atctttaaat atgaaagcat ttacttcatc acctatgttt atttcatttt
    13801 ttccgattaa tctattatga agaagtatat cgtcttttgt gttattagtt tgtccatcca
    13861 aaaaatatcc aaattcagtt tttcttttta ctgtaagttt attaaaatca cctatgttta
    13921 tcaaattaaa atcatcctct cattttatat ttataattta gccataatat acttatgtag
    13981 tagtttgtca cagtatccat attagtatta gtgaaattta caataaataa tatagttatt
    14041 tatgtatttt tcaattctct agcttcttat atagtataaa ctccaatttc ttttttgtct
    14101 ttaggtttta ttaaaatttt tacaaaataa gttaaaaagt attgaaataa aatttctttt
    14161 aaagtataat tggtatatac caaaattggt atataccata tcgaaaagtg gtgactatat
    14221 gaaaatagta aataaatcta gtaatatacc attgcatact caattaagtt caataataag
    14281 agagatgata gaaactggtg agcttaaaga gggcgatgca ataatgccag aaagagaact
    14341 ttgcaacata caaaatgtaa gtcgtatgac agtaaataaa accattgttg gattagttac
    14401 agaaggactt ctttataggg tacaaggtaa agggacattc gttgcaaagc aaaaaaagaa
    14461 gtatcagttt tcaaatgtaa aaggttttac tgatgttatg aaagaaaagg gagtaaacat
    14521 aaaaacggat atattatcct ttgagatgga actaccagat gatttagtta aaagaaagct
    14581 tggaataagt gataatacta caaatatata taagattgtc agacttagat atactgatgg
    14641 agagccattt ggattagaaa tagtatatct atcagaagaa atgtgtaagg gtctaacaaa
    14701 agggatattg gataattctt cattatatag ggttttaaat gaaaaatatg gctataagat
    14761 acaaaaagct gaacaggtaa tggagccagt aatactttca gatgaagaaa gtaagcttct
    14821 tgaaacagat gaaggtgctt tagctcttaa acttcataga aattcctata atagagaagg
    14881 tagccctata gaatatacca tatcaatatt tagaacagat aaatatcaat atgaaatagt
    14941 attgagtgag taggtgaata atatgaaatg tttaattaat ggaaagataa tattaaaaaa
    15001 tcaaatctta gaaaataaag tattagtatt tgatgaaaaa ataattgata tagctgatag
    15061 tgtaccaaaa gattgtgaag ttatagatgc tgatggaaaa tatatatctc cagggcttat
    15121 tgatattcat atacatggaa acatgggaaa agatacaatg gattcgactg atgaatctat
    15181 tgaaacaatt tcaaagtcaa ttatgagaca tggagtaaca tcttttcttc caactacaat
    15241 gactatggat aaagaacatg tttatgatgc acttgaagtt attaaaaaag cccaaaatag
    15301 aaagcttgaa ggggcacaag tattaggagc acatttagaa ggacctttta taaatgagaa
    15361 ttataaggga gcacaaaatg aaaaatttat aataaattca aaatacgaat ttataaaaga
    15421 atataaagat gttataaaag ttataactta tgctccagaa aaagatattg attttgattt
    15481 tactagagaa ataaaaagat gtacagatat agttttatct attggtcata gtaatgcaaa
    15541 ttatgaccaa gctaaagaag ctataaattt aggagtaact aatgtaactc acatgttcaa
    15601 tgcaatgact ggtttaaacc atagagaccc aggcgttgtt ggtgcagcac ttacaactaa
    15661 tgtgtacagt gagttaatag cagatacaat ccatataaat aaagatttat ttcaatttat
    15721 actaaataat aaaggaaaag aaagactgat tttaataaca gattctatag aagctggtgg
    15781 tcttgaagat ggcaattatt ctcttggagg tcagaaagtc atagttaagg gtaatgaagc
    15841 tagacttgaa aatggagcat tagctggaag tgtgttgtct ttaaataaaa tggtatttaa
    15901 cttcttagat aatacaaacc ttaaagtgaa tgaagcaatt aatttagctt ctttaaatcc
    15961 agcaacatct ttgggaataa atgacaaaaa aggaagctta gaaataggta aggatgcaga
    16021 tatagctgta tttgatgaga atttagattg taaaatgaca ctttgcttgg gggacgtagt
    16081 atataaaaat atatagtata caaaacaaac cttaaagaca gtaaaaacaa tataaaaaat
    16141 aataaattaa acttacatta gtaaaagtag tagttaaaat ttaggaggaa taagatgaga
    16201 gtattagtgt gtaaagatta tgatggaatg agtaaaaaag ccgctgaaat gatagcagct
    16261 caaatagttt taaaaccaaa ttcaatactg ggactagcta caggaagtac accagtaggt
    16321 atgtatagag atttagtaaa aaaatacaat gataatatag tagatttttc agatgtgatg
    16381 agctttaatt tagatgaata ttataagtta ccaatatcta atgaccaaag ctatgattat
    16441 tttatgaaag aaaatctatt taatcatgta aacataaagc cagaaaatac tcatctacca
    16501 aatggaatgg ctgatgatat tgaaaaagag tgtatgaact atgaagcttc tatagatgca
    16561 gctggtggta tagatgtaca agtacttgga ataggtcgta atgctcatat aggttttaat
    16621 gaacctgata ctaaatttgc aaagagaact catgtagttg aacttacaga gtctacaata
    16681 gaagctaatg caagattctt taaatcaaga gaagatgttc ctaaaaaagc tgtaagtatg
    16741 ggaataggtt caatattgaa gtctaagaaa atattgcttt tagcttcagg agaagaaaaa
    16801 gctgatgcag tatataatac tgtttatgga gatataactc cagaagttcc tggttctata
    16861 cttcaacttc ataaagacac tatagttata gtagatgaag cagcagcaag taaattgaat
    16921 ccaaaagatt ataaattagt ataagaatag aatgtagttt aagtaaaaaa tagctatcat
    16981 tgagtaatca aatttattta atgatagcta tttttattta aattttttac ttctttttat
    17041 ttaaattagt tattattgtt taaattactt gcttattact ttttacgaaa actcgttatc
    17101 aagaagtatc caaataagat gttaaaaatt attatgttta gtgggattct atcaagcata
    17161 ataaaattac ctataattgg gatattacca actggaaaca taaagaagaa tacaggcatc
    17221 agtgatagta aaaaagatgg aaaacaaaga agaagtaatc ttggaatatc aatataccaa
    17281 ctaccatcct ttttgtattc tctaatcaat aattcagttc ctagtaataa accaatacca
    17341 ccagaggaaa ttaaattaat aaaaatgtat cttttaaagt cttgcatata accagtgtaa
    17401 aattgagtat agaaatcata atttaattta acagctaaaa aatacataag caatagaatg
    17461 attaaaaata aaagatatct aagagctttt ttcattttaa attctccctt cagaaatact
    17521 ttattcagtt ttattttgtt ggaatctgat tttatcattt agtttaagaa atccataata
    17581 ttagtgaaga atgaaataag tattatatat gaataaatat ttttagaatt aaggtgaatt
    17641 gtagtgctta atataactat aatattaatt gtttgaatat tcaataaaaa gtttgaaaaa
    17701 tatcaatttt gatataaact gaataaatac agttgaatat taaattatta ttttatcaaa
    17761 aatatgcaaa gtactacacc ttcaaatatc acctaaagta attaaaaggc aattaaggtg
    17821 aagtagttca agtatttcta aaataagttt aataaattct ataataattt attttttgcc
    17881 ttaaaattgc cttaaaatcc aaacaatttt aaaactaatg tactataaaa agctggtata
    17941 atttaaatat agtaaaaaat aagatttatc ttatctattg ggatttaatt atttaatcaa
    18001 tatatttata ccatttaatt taaataaaaa gtctattaag gagtgagctt atgagtaagt
    18061 taatttatat agcagatgat gaagataata taagaaattt ggtaaagaca ttcttaaaaa
    18121 atgaaggtca tgatgttatg gattttaaaa cgggtgatga acttttagaa caatttaata
    18181 taaaggagtg tgacttagta atactagata taatgatgcc tggctcaagt ggttttgaag
    18241 tatgtacaaa acttcgtgag aaaagtacag tcccaataat catgcttact gcaagagata
    18301 cagatataga ttatattaca gggataacct taggtagtga tgattatttt acaaaaccat
    18361 ttagcccaat gtctttggtt atgagagtaa aatctatatt tagaaggata gagtttgaaa
    18421 agaaacaaaa ttatgataaa tatagtaact cgatagatat ggaattaaaa tttggtgatg
    18481 taataataaa taaaaagaat aaaatcgtta caagtaaaaa tgtaaatata gaccttacac
    18541 caaatgaata taacctattg acttatttgt ttgaaaatat agatagagca gtttccagag
    18601 atgaattatt aaacaaaata tggggatacg atatagaagt tgagacaagg gctgctgatg
    18661 atacagtgaa gagattacgt aaaaaaattt taaatacaaa tattttaata gaaactgtat
    18721 gggggtttgg atttaggttg aaggagaaaa gttaagatga agaatggaaa tgacaagaat
    18781 agaattggaa agattaaatc caaatttaaa ttaaagttct caaagaaaaa tataagcata
    18841 aaaactagga ttttgttgag ta
//
LOCUS       DAYAKB010000071        18616 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.071, whole genome shotgun sequence.
ACCESSION   DAYAKB010000071 DAYAKB010000000
VERSION     DAYAKB010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.071"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            43..918
                     /locus_tag="ACGI3L_002886"
     CDS             43..918
                     /locus_tag="ACGI3L_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HFG9198583.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDINTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            1277..2581
                     /locus_tag="ACGI3L_002887"
     CDS             1277..2581
                     /locus_tag="ACGI3L_002887"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/bile acid-CoA:amino acid
                     N-acyltransferase family protein"
                     /protein_id="HFG9198584.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNNYY"
     gene            2765..4156
                     /locus_tag="ACGI3L_002888"
     CDS             2765..4156
                     /locus_tag="ACGI3L_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HFG9198585.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            4333..4920
                     /locus_tag="ACGI3L_002889"
     CDS             4333..4920
                     /locus_tag="ACGI3L_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9198586.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKSDWNLSI"
     gene            4953..5744
                     /locus_tag="ACGI3L_002890"
     CDS             4953..5744
                     /locus_tag="ACGI3L_002890"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9198587.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(5925..8342)
                     /locus_tag="ACGI3L_002891"
     CDS             complement(5925..8342)
                     /locus_tag="ACGI3L_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9198588.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(8355..9020)
                     /locus_tag="ACGI3L_002892"
     CDS             complement(8355..9020)
                     /locus_tag="ACGI3L_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198589.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            complement(9102..10133)
                     /locus_tag="ACGI3L_002893"
     CDS             complement(9102..10133)
                     /locus_tag="ACGI3L_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9198590.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSRICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            complement(10123..10809)
                     /locus_tag="ACGI3L_002894"
     CDS             complement(10123..10809)
                     /locus_tag="ACGI3L_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198591.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            complement(10967..12031)
                     /locus_tag="ACGI3L_002895"
     CDS             complement(10967..12031)
                     /locus_tag="ACGI3L_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reductive dehalogenase domain-containing
                     protein"
                     /protein_id="HFG9198592.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            12293..12964
                     /locus_tag="ACGI3L_002896"
     CDS             12293..12964
                     /locus_tag="ACGI3L_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198593.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            12966..13874
                     /locus_tag="ACGI3L_002897"
     CDS             12966..13874
                     /locus_tag="ACGI3L_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9198594.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            13951..14637
                     /locus_tag="ACGI3L_002898"
     CDS             13951..14637
                     /locus_tag="ACGI3L_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198595.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            14634..17189
                     /locus_tag="ACGI3L_002899"
     CDS             14634..17189
                     /locus_tag="ACGI3L_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9198596.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIEVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(17383..18582)
                     /locus_tag="ACGI3L_002900"
     CDS             complement(17383..18582)
                     /locus_tag="ACGI3L_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HFG9198597.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
BASE COUNT         6919 a         2325 c         2716 g         6656 t
ORIGIN      
        1 aatttatttt attgatgaaa ctaatgggga ggttaaaact caatgattac ttttgatgta
       61 aatggagcta ttatcagatt tgatgataca aaaaataatt ataataagat aaggaaaatc
      121 tttaaattat atgctttgga aatatctaaa aactttgaga gagattgttt aaatagtttt
      181 caaaatctaa agcaaatatc tgatagaggt ttaagtttag gagaaaaata tatagaagag
      241 tcttttaaga aaggaattga gactatagta agttttggaa ttataactat agatatcaat
      301 acctttaaaa gtgtttattg tgaaaaatat ttagatttta agagactttt taataacttg
      361 aataaaactt ttattatacc aaataaaaat aaaaaaaatg gccacgcgag cttcttagaa
      421 atagaatcga caataaagaa aatgagcaat tatttataca atgattgttt taaaattcat
      481 tatgctgttg tagatgccct tatagaaaat cgtataactg cggtacattc ttatattgat
      541 gaagaatcta taaaaaaatc taatgcctta tttaataatt ataaagatgg ttttattggg
      601 aaggctgacg aatgcaaagt agtaaaacaa ataataactt taaatccata tagggaagat
      661 gtatacgaat ttttggtaaa agaagatgga gattttagta aggaaattga gagattgact
      721 gaatttttag gctatgatat aagagaatat aaagcgtcat taatggatat ttatataaat
      781 gagttaatgg agagcgatga aaatgatgtt gaaaatgcaa aagaaaagat tgaaaaatat
      841 gctagatata ttggatgtag tgatgagaat ttatatgtag caagagttaa tgccatatat
      901 acttttgcaa atgcataatt ttattaaaca ttaaatatta gatgttcgat tatataaatt
      961 taaataaaaa aatatcctta ttaataacaa atagtttata ttaaaaacca ttcttaaaat
     1021 gagtggtttt ttattttgaa tatatatatt ctaaacctaa tagcattcct atctttaatt
     1081 agccaaaaat caactggatt tcatatagac tacataattt taaattgcta aaaaagacaa
     1141 tatgttgaca aaaatagaat atgttgataa aatgaaatag tcaatatggt gtcttaattt
     1201 aaaaatttat ttatgttgta ttagataaag ctgttttata taaaacataa ataattatta
     1261 taaggagaaa tagattatga aagtaaatgt atacaatgta gaatcatttg tggatgaaag
     1321 acttaagatt atggtttcgg acttaattcc aaatactaaa cttaaaataa gtgtgaaaat
     1381 ggaatttcca tggtgcaagg gagaagaatt ttcatcttat ggagtgtttt gttcaaatga
     1441 aaaaggagaa gtagatttag atttagttga acctatagaa ggtacttata aggctgataa
     1501 ttgtatgggg ttaatttatt cgctggaaaa atctaaaact gaaggtaaaa attttgcaga
     1561 aaatatatct attgataaac caataattat gaatatgata tttgaaactt ctattgaaag
     1621 aaaagaagtt gaattaaaga gaatatttaa atcagaagat attaccacaa aatatatatc
     1681 tgatgagttt ataggaaaat tattttataa acaaaattct aataataaaa caattttaat
     1741 gctaggtggt tctgatggaa atttagacgc tctagacctt ttagcagctc cacttgcatc
     1801 tagaggattc aatgtactaa cagttgcata ctttgcttta gaagggttac cagataaatt
     1861 agaagaggtt ccattagaat attttgaaaa agtatttgag tggattagtg aaaatgaaat
     1921 taccagtact aaagaaatat ttgtacatgg gacatcaaag ggtggagaat tggccttttt
     1981 acttgcttca agatatgaac aaattaaaaa ggttgtagta tcacaacctc acatttattg
     2041 tttccaagct cttaatggat tgatgagtgg aaatgatact tcatcatggt catataaagg
     2101 agagccattt ccatatatca aagtagacaa tgatatattc tttgaagaac agaaaaaaaa
     2161 tatatcaaaa ggtattccat ttggatttaa tagtacttat aagaaaagtc ttaaaagagc
     2221 agagaataga aaagaggcta gaataaaaat agaaaattcc aaagcagata tacttatgat
     2281 tgctggaaaa gaagataaca tatggaatag ttatgaagct tgtttaaagg cattagaaat
     2341 ctttgaagaa aataattatc catataacgt agaattatta acatacaata atatgggtca
     2401 tccgttacca attccatata ttatgcctct aaaggagact ttatgtatga gtatgagtgg
     2461 agggattttt tcttcaggtg gaactgtaga aggaaattca aaaggacagt ttgaatcatg
     2521 gaatagaact attgaatttt ataaaaaacc tttatcaagt gatttaaata actactatta
     2581 agtgatttaa gtaactaaaa atgaagcggt ctttctatat atgcacaaaa tctatcaatt
     2641 ttatagattt aatttattgt ttatataatt tgcatgttat atactaattt taatgacatt
     2701 gataatttat aaacaattat aaagttgtaa acttataaga gttattgaaa ggtggagtga
     2761 agttatggaa agactcgcta gaagggaaca acctcatata aaatttggaa tgtttaagat
     2821 aagaattcca tttatacatt acagatttga gaaaccagaa gctattcaag gtataatatc
     2881 aagtatgaca agtttaggca caattggcct tagtacacaa attttgggat taccctatga
     2941 agtggcatgg agtatggcta tcattaactc aatattatac tgtttgcatg tttttatggg
     3001 agacccagtt gtacctggct ggattacagc ttctataact cttacaactg catatttgtt
     3061 aaagttcagc atgggcattg aaagaataca agcattaaca gctttacaaa tagatttagg
     3121 aataatattt attttaatgg gtataactgg tgtagctgga aagttagtta gtaagatacc
     3181 aaattctatt aaaggtggaa tactaatggg tgtcggtata tcgactataa tatcagagtt
     3241 taatcctaaa gggagatttg attcttatcc tatatctata acagtaggaa ttttggttgc
     3301 ttgttttgta atgttttctg aaagatttga tactctaaaa gttaagaata aatttttatt
     3361 tcatttagga gaatatggtg tagtatcagc tattttagtg agtttaatag taggtatatt
     3421 tagtaaagaa atagaaattc ctagatttag ttttgacaat ttagtttaca tagtagattt
     3481 taaaaatctg ataaatacag tatctccttt tggaataggt tttccaagtg taatgttatt
     3541 tatacaaggg ataccaatgg cttttatgat atacataatt gcctttggtg attttataac
     3601 aggtgaaaac ttagtacttt ctgaaagtga aaatagaaaa gatgaatata tagatttcaa
     3661 ttcaaatagg tctaatgtta taagtgggat aagaaatatt tttatggcaa tcttttctcc
     3721 atatatacca atgtgcggtc cattagctgc gacacttaca ggaagtgttg ctcaaaggta
     3781 caaggttgga aaggaagcca tgcagtctgt ttttagtggc atgggtacat tagtatgggt
     3841 ttcagcaatt tttatctgtt tttatccaat tgcgcagatt gctacacctc ttataccatt
     3901 agcattgtca gtaacacttt tagttcaagg atatttatgt acaaagctat caatggagct
     3961 atgtaataca ggtgttgaga agggattgat tggacttatg ggaggtgtaa ttgctgctaa
     4021 aggcggaaca tggggacttg ctgtaggttt tatactgtat ttcattttaa ttgattctaa
     4081 aaaaagaaaa gaaaaagata ttaattcaat agaagattgt gtatatgaaa tattagacaa
     4141 aaagaagagt atttaaagga aaatctgagt tgctgttatc tattaataga ttaattgcaa
     4201 ctcatgtttt atttataagt tttaggaatt gcaaaaaaat gcaaagcttt ttcttgacat
     4261 aatttcttga tatgttacta tagttatata acacatgtgt tttataaaaa tttaatggag
     4321 aggtgaacat atatgccacc taaagtaaag ataacaaaag aaatgatttt gaatacagtc
     4381 ttggatatta caagagaagt gggatttgaa gctgtaaatg cgaggagtat tgcaagtaaa
     4441 ttacagtgtt ccactcgacc aatttttact tgttatgaaa acatgaatga attaaaaaat
     4501 gaatttcttg cttttgcata tgaatattat aatcagtatg ttgttaatta tcgtaattct
     4561 aaaagtgtaa gcccttattt actgcttccg ctttcataca ttgaatttgc tcaagaagaa
     4621 acgtatttat ttaagttgtt atttataaat gatttagatt tgatgatgaa agaggcgaat
     4681 gatttttata aagaaattga caatgaaaaa aaggcaagac ttttttcgga aagcattgga
     4741 atagatttgg aatgtgcaaa agtaatattt ttagatttat ttctttatac tcatggcata
     4801 gctgtcttaa cagcaacaaa aaaattaaca ttagatagat atagtgctga aaaaatgttg
     4861 aaaaatatat taacagcttt tataagacaa gaaaaatcag attggaattt gtctatttga
     4921 tgtttattaa ctaatataga agaggtgaaa ttatggaaac aaaacaatac ttaattgact
     4981 tttataatac ttatgatgaa gatagtcgac ttgcattaaa acatggaatg gtggaatttc
     5041 tcactactat gcattacatt gataagtaca taaaatcagg tgattgtgtg cttgaaattg
     5101 gcgctgcaac tggtcgttat tctcacacac tggcacgtca gggatatgat gttgacgcag
     5161 tggaattagt cgaacataat atagaggttt tccataaaaa tactcaatca aatgaaaata
     5221 taagcattac tcagggtaat gctatggatt tatctgtttt cccagataat aaatatgata
     5281 ttacgttact gttaggacca ctatatcatc tttataacaa agaagataaa caacaagctt
     5341 tacatgaggc aattcgtgta acaaaacctg gtggtgtggt ttttgctgca tatgttatat
     5401 ctgatggctg tcttattgac gaggggttcc atagaggaaa tattaatgta tctgaatata
     5461 ttgaaaaagg tttgattgat ccacagacat ttgctgctaa gtctgaacca aaggatttgt
     5521 ttgagcttgt acgtaaagaa aacattgatg atttgatgtc tgcatttaat gtaactagac
     5581 tgcattatgt cgcatcagat ggtttggctt tgtatatgcg tgaagcagta gactctatgg
     5641 atgatgatgc atttgcatta tatttaaaat atcaccttgc tacttgtgaa cgtgaagatt
     5701 tagtaggggt tacaagtcat gcaattgaca tatttagaaa ataaggaata tgcttgttta
     5761 tgtctctggt gatgttgctc ggagatataa gtaagtgtat ctgtataaaa taaaaacaag
     5821 tatagggata gaaaattatg taaagtcaaa attttctatc cttttagctt ttaaaaaatt
     5881 atgttaaaac ttgtataaaa aatggctatt ttttatatac attcttactg agaacgtaag
     5941 cgttctgtaa gtgatttttt ttctatattt cttacaagta attcagtcac taaaacttgt
     6001 ataccaatta atacgaatga aaaaattaaa atagtaaata tagaaaattt aaaattaata
     6061 aagtctaatc taattacatc ttttataaaa gtgcaaagta gatttgaacc aaaataacct
     6121 agtatacttg aagtacatat agctttgata cttatgttta gaccttctct ataaagcata
     6181 tttcgcagtt gctttcttgt cattccaacg gcttgaagta atgcaaactc tttttttcta
     6241 attaaaacgc tgtttattag ggtattggtc atatttagta taccaaagca agaaattaaa
     6301 ccaacaaaaa tgtatgaagc tataattata tattgaaatg ctctagtaat cattctataa
     6361 tcatcttcat atgaataaag cattaaattt gaatttttct gaattatact taacaacttt
     6421 tcttcaactt ctttagaatg ctttttatct attaaaatag aaaaatctaa atttgtatta
     6481 tatggtgtta gagattctaa agttttgtct gaagcaaaaa acatacctcc tgtattggaa
     6541 ttgtcaatga ttcctataat tttcattttc tttttaataa tatcatttcc actaaagata
     6601 ttaaatgtaa ctgtatctcc aacttttaaa tttaatccat aatattttgt tctatattta
     6661 tttataatta aactatctga atctaaatgt gtatagtcta tttttccact gacaatatat
     6721 tcttcaagtg attttgaaag ttcaggcgta atacctttaa ttagagtaat aaattgtttt
     6781 tcgtctctat ctttgatgta aggttctata atattacttt taattgattt ggattcaatt
     6841 aattttttta ctccatgaat agatttaatt tcattcttaa gagaatctgt tagtggatta
     6901 ttttgttgga tttctgtaat atgctcatat aagttatcac tcttaatgct aattatataa
     6961 tcttcgttat agacaaattg ttgagatagt tgttttttga aatctattga attagcaaga
     7021 ttagcgattg aaataaataa aactccacta atgcttagcg atattaatgc aatcaaattt
     7081 ttctttctat ttgactcgat attctttaat gctagatttt ttatatttat ataactaaaa
     7141 ttttttgctt tttttctaaa tttagtttct gtatattgca tggcttcaat agcagatatt
     7201 ttagaaataa ttctagctgg tttaaataaa gaaattctaa cagttaaaaa cattaccagt
     7261 gataaaatta aaattataaa taaatcagct atcatttgcc atgctaatgg ttgaattatg
     7321 taagcaatta tacaagaagc tataacccct aatggaataa aaataattga caaaatattt
     7381 ccttgtagag aaataatttt ttttaactga aaagaagtca tacctaacga tttcaactta
     7441 gcatacatct gaactgaatt aacaactgaa atataaaaaa tactatatat aacaaaaacg
     7501 ctagaaaaaa gaacaactat tccaactact aaaactgtaa taatctgctc accatcaatt
     7561 aaatttgatt caatatagtt atcatttaag tatatattat atttcttaat acctaaagat
     7621 aaaccaattt tatttaactg tgtcttaatt gaagctgaat ctttctctgt attttcttct
     7681 gatagtttaa ctaatacatc tacagtatca ggtcttgact cgtcaaaagt attactttta
     7741 ttttgtaaag gtgtagaagc tatattctta aaataatcat ttgaaacgac tgtatagtat
     7801 tgcttggcat tatcttgata ataattttct agaaatccaa caataataaa atcacattga
     7861 acttctttat tcgtaatatc atcataataa tttaatttaa tgctatctcc aatatcttta
     7921 tctaaaccaa attcctgtaa atatttttct gaaatagcaa tttcattttt atttgtaggt
     7981 agtttgcctt tcaatggttg aaaattcata agtttaattg ctgtatcatc tgcataaaca
     8041 atcgacataa tacaatctgt ctttttatta cttccaatta atttgtaagt tcctacgcca
     8101 ctaaagtttt tatctttata tagtatattt tttgcttttt catctacaga tttatatata
     8161 gcatgatatg gagatgcatt aactaaatct acagaggcat tatatgaaac taaggtcact
     8221 gttaataata aacatgtaga aatcattata atgatacctg aaagatatgt tttaagttta
     8281 ttaattttta aatcatttaa agctattttt cttataaatg tgcgattatt atttctaaac
     8341 atatactaca cctcctagtt aacaattttt ccatcttcaa tacgaataat tctatcagtt
     8401 agttgtgcaa tttcattatt gtgtgtaatc attacaattg tttggttgaa ttttttactt
     8461 gtcactttaa gtaaactcag tacatctgaa ctagttctac tatcaaggtt acctgttggt
     8521 tcatcagcta gtataatagc tggttttgtt acaagtgctc tagctatagc aacacgttgc
     8581 tgttgaccac cagaaagatt acttggtata tcatataatt tttcttcaag agaaagcata
     8641 tttataattt catttataaa atccttatct atggtctctc catccaatcc tattggtaag
     8701 ataatatttt catatacatt aagtaaagga acaagattat aattttgaaa tataaaacct
     8761 atatttctgc gtctaaagat tgtaagctgt tcatcagaca tagtagataa ttccttaccc
     8821 tttataataa cctttccaga tgtaggatta tctaatcctc ccatcatatt taataatgtg
     8881 gatttgccac taccagatgt acctacaata gaaataaatt cgcctttttc aatagataga
     8941 gttacaccat caagagcttt tgtaatgttt gaactttgtc cataatattt ctttaaatta
     9001 attacttgta aaatactcat aataatacct ccttaacatc ttgtaaatac agtataaaac
     9061 caaaatgttg cagaatcatt acaaatgaaa tatttaaaaa tttatttatt aggtaagaaa
     9121 atagaaaaag tcgacccttt tccaatatct gatgtaactt taatatagcc accttgaaga
     9181 gatataattt ttcttgaaag atagagacct attccaatac cttctatgtc atggacatct
     9241 tcttcacgat aaaatctttt aaagatttct gcttggcgac tttctgatat tccttttcca
     9301 ttatcaataa tatctatttt tgtatacata acccaacatt ctgtagctac acgtatctta
     9361 ccattagaac ttgtgtattt tacagcatta tctaatatat taaaaatagc ttcagaagtc
     9421 catttcttgt catgaattat atataaattt gggtcacaat caactgtaac ttcaatattc
     9481 tttttttcag catcaaacaa aattccacta agtgctgtag caattgtttc ataaattgaa
     9541 tttttctttt tagatagtgt gattatacct gtctctagtc tggaggtttt taccatagat
     9601 tgcattaaaa aatctaattt atctaattgg ttttccatat ccattaaaaa atccttttga
     9661 atttctgttt taaatgtttg atttagtaga gtagtattaa tcatttttaa atttgcaata
     9721 ggagttttaa tttgatgaga tatatcagaa actagttctt gtaaatcagc tttctctata
     9781 gcaatactat tgcgattttc ttgaataact tcatacattc taattaatct gtgattgata
     9841 cgtgataaaa tagtttcttc ttctaattca atttcaatat tatcttcact attcatcata
     9901 ctatctaaag tgtgacatat tctagaacaa aatataacta tttttttatg aagtaaaaat
     9961 attattaatg ctataaatcc acaaagtact attgtatata ttaataatag agcaattagt
    10021 tttaaatcat cagttattag ataaattgag atactaaata aaatagctgt aaaaattata
    10081 ccaacagcaa ttattaaata aatagaacta aaagaaaatt ttttaaaatt catttctttc
    10141 acctaaccac atatatccca taccatatac cgttttgata tacttaagat tgtctttttc
    10201 aattttgctt ctaatcctac ttataacaga tgttaaagta tgttcatcta caaagttagc
    10261 atctatatcc cagagttttt ctaaaagtac tttccttgtt aaaatacttt taggattttc
    10321 agtaagcagt tttaaagtac gatattctaa tggtgtaaat ataatttgat ttccatttat
    10381 attggcagat aactcagaaa agttaatttc aagatatcca tccctatagt aatcttgttt
    10441 tgtttttatt gtaagatgat ttaaaaaagc tttaattttt tgtttaaata tattgatatt
    10501 aaatggtttt gttatataat ccaaagctcc aagttcatag cctttaatca tatcacattc
    10561 catatcatta gcagttaaaa aaattattgg tatattgtaa ttttccttta tttcattaca
    10621 taattcaaac ccacttttat ctggtaaatt aatatccaaa attattaaat caaattcaca
    10681 ttcaaaaata gactttagtg cagatttagc tgtaaatttt gaagtaatta tatatccatc
    10741 ttcaattagg ttatatgata gagttttatt taatatagaa tcatcttcta ctactaatat
    10801 tttttccata cagttactcc ttttagttta atattttata atgtcaatta tagactaaaa
    10861 acattgctga attgttataa acgagaaaaa gtatttaaaa atttatatat ttaataaaga
    10921 acctgtccta tgataaattc tagtacagat tctttattaa ataaaattat ttcaaccaag
    10981 atggatttcc aggtataaat attcttttac caaattttga agtatactca tctaaagctt
    11041 tttgaataag ctcattatta cccttaaatg aagtagtatt ctttatagtt tcgagatttt
    11101 ggctaaatgg gcaagcagat atacacatac cacaatctgt acctaaatat ctccatttaa
    11161 tatagcatgt ctcatgttca attacccaat tatattttcc atcatcacca attttaatat
    11221 cattagaaag cgaatgagaa gggcagttaa aagagcattt tttacagacc ttacaaaaat
    11281 cttctagtcc aaaatcaaca tattcatctt ctaaaagagg aatatctgta gtaacaacac
    11341 ctaatctaag tctagagcca taatctttat ttgtaagtat agcatttctt cctatatctc
    11401 ctaaaccagc atcacgagct ataaaaacag gcattactaa ataattagca tccatatgat
    11461 ttctagcatc atatcctaaa tttcttatat agtaacttaa aatcatgccg acgatagatg
    11521 catccacata gcactttgat gtttctataa cttcacatat cattggagct ctatttatca
    11581 tttctttatc catctcacat ccaaatacaa ttgcatactt atgagttaga ttaatttctt
    11641 caccgtaatt ttcttcatgt ctacccctat ttgtataaat atgatagtct tttaatttag
    11701 ttataccaac tacagaagct ccatactgct ttgcaagacc cttaattttt tttgtcattg
    11761 actttgcatc tacatctact ttagtatcag aaacttttcc ttcgcataaa gatttgatat
    11821 cagataaaaa atcgaatgca ctacttgcca ttggagagtt taactcattg taagtcattg
    11881 ttccttcact acataaattt ggtctatttc ttatactatc atcaatttct tttttgtcag
    11941 gatttttctt ataatagtca ttataagcag tactatcttt tttgtaattt gctcttgcaa
    12001 acatagtatt tctctcatca acccttttca attctattcc ccctagtaaa aatatattta
    12061 aaaaatataa ctttattgtt gtataattta attatataag aataaagtta tattttcaat
    12121 ttaagcgtaa ttaaattggg aaatatataa ctatatgctt gattataatg tttttatttt
    12181 gaaaacaaat ttaaatacaa tctttttagt gaaataaata aaattaaaat atttttagta
    12241 tgataatgca agaaaataat tatttatcta aaaaatctaa aggagagtaa aattgaactt
    12301 attaattatt gaagatgata taaacttaaa tgaaggtctt ttttatgcat ttgagaatga
    12361 tggatttaat gtatttaagg cttatacaaa acaagaagga ttaaatatat ttaatagtaa
    12421 aaatatagat tttataatct tagactgcaa tcttccagat ggagatggat ttgatgtatg
    12481 tcaaataata agggaaaagt cagatatacc aattataatg cttactgcaa gagactcaga
    12541 aattgatgaa gtaaaaggat tagaaatagg gcttgatgat tacattacaa aaccattttc
    12601 tttatctgta ttaaaggcaa gagtcaaagt agcaataaga aaaaaatcga ataataaagt
    12661 aatatattcc aatggaataa aattggacca aaagttacta aaagtatata aaaataaaga
    12721 atgtttggaa cttagctctg tagaatataa gcttctaagt tatctaattg aaaataaagg
    12781 tcaaatatta ttaaaggaac aaattttaca ccatatttgg gacagcgaag aaaattatgt
    12841 tgatgataat attgtatctg taaatataag aagacttaga gtaaaagtag aggatgaccc
    12901 atctaatcca aaatatataa aaacagctta tggaatgggt tatttatgga atgaggtaga
    12961 ataatatgtt tatattagcc tttataatat gtacagttgt tatatttata gtatctacta
    13021 aaataaatcg aaaaagatat gatgaattaa atttgatgtt aaatcaaata ttggaaggta
    13081 aagaagttac ttatccagat acaaaggata caagagcgtc aaaaatttct caccaagtaa
    13141 aaaaaattaa ggatatgata gaaatagagg tagaacagtc aaagtcagaa aaagaagcga
    13201 ttaaaggttt aatatcaaat atgtcacatc aattaaaaac tccactttca aatataacca
    13261 tttattgtga acttctggag aatataaata tttccacatt acagaagaag gagtttttac
    13321 aaaagatgaa aaatgaaact tttaagattg actggctgtt acaatcctta tttaaaatga
    13381 ctaaattaga ggatggagtt atagaatttg aagtagaaga actactaatt aaagatactc
    13441 ttattcaaag tatcagtact atctttaata aagcagaagc taaaaatata aggataaatc
    13501 tcgaaccatt ttcagacata aaattagttc ataataaaaa gtggaccata gaagcaattg
    13561 taaatgtttt agaaaatgca ataaaatact caccatcaga tagcacgatt actatttctg
    13621 taataaaaat ggaactatat acgaagatta ctattaaaga tgagggaata ggtattgata
    13681 gtagagaact aaatgatatt tttaaaagat tttacagaag taaaaatgtt gaaaaccaaa
    13741 atggcacagg gattggtcta tatcttacaa gattaatttt agaaaaagaa aatggaaaca
    13801 ttatagtaga atctaaacta ggaagtggat gttgttttag tatcttctta cagaattgta
    13861 agagtttaaa ctaattttgt aggatgagtg taattatcgt cacttacaat attttataga
    13921 acatatatct gtattgaaag gagaaattaa atgagtatat tagtgacgaa taatttagta
    13981 aaacactatg gaaaaggtga gactaaagta aaagccttaa atggagtaag tatagaaatt
    14041 gaacgagata catttactgc tatagttgga acttctggtt ctggaaaaag cacattgtta
    14101 aatattatag gtggattaga taatccaacc tcaggtgatg taataattaa aggaaagaac
    14161 atatctaaaa taggaaaaaa agatttgaca gtgtttagaa gaagaaatat aggatttata
    14221 tttcaaaact acagtttaat gcccgtatta aacacttatg ataatatagc tcttcctgtt
    14281 acattagata aaggaaacca tatagaccat gaatatattg aaatgctgat gaagacattg
    14341 ggaatttggg ataagcgttt aaaatttcca agcgaactat ctggtggtca acaacagagg
    14401 gtagcaattg ctagagcttt ggcaaataaa cctgcgctta tattagcaga tgaaccaaca
    14461 ggaaatctcg atagtaaaac tacaatggaa gtggtatgtt tattaaaaga aagtagtgca
    14521 aaattccatc aaacgatact tatggtaaca cacaatgaaa atatagcaca agtatgcgac
    14581 tcaattatcc atattgaaga tggagttgtg gtgaatactg gtggtgaagt actatgatgt
    14641 ctctagtaaa attttcaatt caatatataa agcattataa aaaacaatct atatctatag
    14701 ttttaagtat agtactatca gtagcattat tgacgggaat tggttcttta gttcatagtg
    14761 cagacaaaag tagaattgaa aagataaggg aagatagtgg agattatcat tatttctata
    14821 aagtagataa ggaacaactt aataaaatta aaaaaaataa aaaatcaaag gaatacactg
    14881 tagatagact tggcgttaca aaacctaaaa atcagataga tgaacctttt attatagaat
    14941 ttttaaatgc tgattcttca tatttagaca tgacaggtag aaaattatta aaaggaactc
    15001 ttcctagtaa agatggagag atagtacttg acacatattc tctaaacaat ttaaatgtaa
    15061 acaaagaaat tggaacagaa atcaatttag atggtaaaat ctataagtta tgtggtattt
    15121 tatcaagtct ttcaaaccca gaaactgctc tggagggatt tgtaaacgat tattttcagc
    15181 ctaaagaaaa ggattcttat atagtttatg taaaatatga tgaaaataaa aatattaaaa
    15241 agcaaaatta taaatttatg aaaaaattca acatatcaaa agaaaaaact tatataaact
    15301 ggcctctttc agttgaattt ggagtaaaac caccaaaaaa tatagaaaaa tataatatat
    15361 ttgagttctt aaaaaattta gaactaaata caaatgcaat tatattactt gttggagtgt
    15421 ttggtgcagc agcagtatat agtattttcc atgtttcaat acttcagaga atatcacaat
    15481 atggggtttt agaagtatta ggcgctaata ataaacaact tttatttcta ctatttttag
    15541 agttattttt actttttatt gttggatttc ctataggttg cttcttaggt attgaagtgg
    15601 cgtctacaat atatgaacaa tttccacata tatttttgag tagtgatatt gttccaggag
    15661 cattttttat aagtgaaaaa tctatttatt taggcttttt atttatctta ttgttgttaa
    15721 ttttaattgc tgtacgtgtt gtacatcagt tgaataaata ctctagtata gaatctatga
    15781 aaaactttaa gattactaat aagaaaaaga gaatattaga aagtgtaaaa cactctaaca
    15841 tgacaaaagt attatctcat aaatacatga ctcaaaaaaa gggaatgttt attggaattt
    15901 tgttttcatt atcacttggt ggaattatat ttttatgttc tagttactct atacagctta
    15961 ctaaaaataa taatgaactt acaatgaaag ctgatgatgg tttaaattct gactaccaaa
    16021 taactatgca aacaacagat tttgatgtag gtataccaaa agataaaatt tcaagattaa
    16081 acaatgttga gggaatatca aaagtctatc cagtaagata tttatttgga gctatgcaaa
    16141 ttaaagaaga acaactattt tggaaaaatt tctttaaacc tcttgaaaaa gattacagga
    16201 taaagacttt ttttgatggt atttgtacaa agcaaaatga aggtggctat cttttaaaaa
    16261 caaatattta tggttataac aatggtatgt tagaaggatt aaattcttat attatagatg
    16321 gggagattaa tacccatgat atggttaaaa ataataaggt tatagttaga ctacctatgg
    16381 atggaactgg gatgtatgat gcagttgata taaatccagg agatacaata aaagttaaag
    16441 tgccaaagac aatgaaacca acagatgaaa ttgttaaatt taaagaagaa aataagaatg
    16501 attatacaac aaaagaattt gtagttgctg ctactgtaaa acgtgtgatg gcaaataaca
    16561 tatatttcat tggtgattat ggtatggata tagttatgac gaatgggcaa atgaaaaata
    16621 actttgatat cgaaaattat aattcagtaa gtataaaaaa gacagaagat agtaacagtg
    16681 aggaattgtc tgagaacata aaaagtgttg taagtgatgt aaaaagatgt atcgtaacag
    16741 attataccat tgctattgaa aaaaataata cctacttaaa tcaaaaactc ttatttatat
    16801 atggtattgt atttgtactt cttgcaataa gtttgttcca tataatcaat acagtaagct
    16861 acttaatttt ttcaagaaga catgagtttg gaattttaag agctatgggt attacggata
    16921 ataagttttt acttatgatg ataagagaag gttttttata tggattctat gcaagtatta
    16981 taatggtaat tggaagtgtt attggacaat ttatgattta ttttatggta aaacgtgtat
    17041 atttatatat aaatccaatt cttaaaataa atacacctct atacataggt atgattattt
    17101 taaatatcac tattagtata gttgctgtaa ttattccagt aagacaaatt ttgaagagtg
    17161 atattatttc agaaataaat aagaattaga gttatataaa tttttaagat tatataactt
    17221 tctgacaatc ttgtttaaat tatttaaata tatcttatct gtgaacatta aataaacctc
    17281 ttaatagata taactcttga aaagtcatat ctattaagag gttttaataa attttcatgt
    17341 taatatatat aatccaaaaa aattaaatct tattaaaaca tactattttg tatagttatc
    17401 gaaatatcct tgtatgtaaa taataggagt acccttatct ccacttccag atgttaaatc
    17461 tgctaaagaa cctataaggt ctgttaatct tcttggagta gtaccttgag aaaccatgtt
    17521 tcctgttaaa tcatcagatt tattatcttt ttcaactatg tattttgaaa ttgcttcttt
    17581 taactcatca ccagataagt cagcaaaatc attatctgct aagtatttta attttacttc
    17641 gtttggagtt ccctctagcc cttttgtata agcaggagat actactgggt cagctaattc
    17701 ccatatttta cctacagggt ctttaaaagc tccatctcca taaaccatta cttctacatc
    17761 tttccctgtt atttctttta tattaccttg gattttgttt acaacttcat cacaatttat
    17821 agggaataat tttactgttt cttctgtagc tttgtttgaa cctaaaagtc catactggtc
    17881 attgtaacca ctaccatcta cacttgctgt cattatatca tcaagtgaat atactttttt
    17941 agctccattt tgtcttaaaa ttctctttgt tctttgtctt gtatgtatat cacaagttaa
    18001 aatacttgtt gtatagttaa gaatagtttt tggattgttt gcaaatacta tttctacctc
    18061 tgcaccacaa tccttgatta aattcttata ataatcaaca taatctacac cagtaaatgt
    18121 atgcttgtta tatccaaata gttctctgta tttttcttct gttaaaacat ctgaccaagg
    18181 atttattccc ttatcatcaa gttcatcaat acttattaag tgatttccaa cttcatcaga
    18241 agggtagctt aacattaata cgacttttct acatcctttt gcaattcctt ttaaacatat
    18301 agcaaaacga tttctactta aaattgggaa tataactcca acagtatcat ctccaaattt
    18361 atcttttaca tcttttgcaa tattgtcaac gtgagcataa tttccctgtg ctctagctac
    18421 aacagcttct gtaacggcaa ttacatcttt gtccctaact tcaaagtttt cactttttga
    18481 cgcatttaaa acagaatcaa caactatttt aactaagtca tctccttgtc ttataatagg
    18541 tgctctaacc cctcttgaaa cagttccaac taatctatcc attatctaaa atcctcctaa
    18601 agaattaata ttgtca
//
LOCUS       DAYAKB010000072        18243 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.072, whole genome shotgun sequence.
ACCESSION   DAYAKB010000072 DAYAKB010000000
VERSION     DAYAKB010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18243
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.072"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..867
                     /locus_tag="ACGI3L_002901"
     CDS             <1..867
                     /locus_tag="ACGI3L_002901"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9198598.1"
                     /translation="TNANVIKKFYTDDELEAVLVAKSDVLVDALAAGPLAANLKSPIL
                     ITPKTYVSAYHKDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGK
                     TVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGN
                     RTALSNSLKPDLFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNILNRILEKF
                     KLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAVLVECAFLDNENDMSLINSSAKVKEMG
                     TQIGKGIEDSLK"
     gene            1109..3022
                     /locus_tag="ACGI3L_002902"
     CDS             1109..3022
                     /locus_tag="ACGI3L_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198599.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERSLRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYREILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            3015..5234
                     /locus_tag="ACGI3L_002903"
     CDS             3015..5234
                     /locus_tag="ACGI3L_002903"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFG9198600.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDNLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            5343..6173
                     /locus_tag="ACGI3L_002904"
     CDS             5343..6173
                     /locus_tag="ACGI3L_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFG9198601.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            6163..9630
                     /gene="addB"
                     /locus_tag="ACGI3L_002905"
     CDS             6163..9630
                     /gene="addB"
                     /locus_tag="ACGI3L_002905"
                     /EC_number="3.1.-.-"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HFG9198602.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            9630..13457
                     /gene="addA"
                     /locus_tag="ACGI3L_002906"
     CDS             9630..13457
                     /gene="addA"
                     /locus_tag="ACGI3L_002906"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFG9198603.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGCRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVNNPDSDY
                     YGEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            13503..14714
                     /locus_tag="ACGI3L_002907"
     CDS             13503..14714
                     /locus_tag="ACGI3L_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFG9198604.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            14701..18228
                     /locus_tag="ACGI3L_002908"
     CDS             14701..18228
                     /locus_tag="ACGI3L_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9198605.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKDNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
BASE COUNT         7947 a         1698 c         3237 g         5361 t
ORIGIN      
        1 acaaatgcaa acgtaataaa aaaattctat acagatgatg agttagaggc tgttttagta
       61 gctaaatcag atgtacttgt tgatgcttta gcagcaggtc cattggctgc gaacctaaag
      121 tctccaatac ttataacacc aaagacgtat gtatctgcat accataaaga taatttagaa
      181 gctaaatcag ctaataaggt atacaaaata ggaggaggat tgacttctaa ggtaatgagc
      241 tctatagcat catcattatc taaacacaat acgactccaa cagaaccagg aaatagtggg
      301 ggcaagacag ttatgattga cccagggcat ggtggttcag cacctggaaa ttcatctgga
      361 ggaatgattg aaaaagatta caatttaaat acttcacttg caacaactga atatttacgt
      421 tcaaagggat tcaatgtaat aatgacaaga gacacagata agactttatc tcttggaaat
      481 agaactgctc tatctaattc attgaaacca gatttattta caagtataca ttataatggc
      541 tcaactaata aacaaggtca tggtgtagaa gtattttata agcttaaaga taaaaatgga
      601 gggactacta aaactgtagc taccaatata ttaaatagaa ttttagagaa atttaaactt
      661 acaaatagag gtataaaaac aagagtactt cctagtgatt ctacaaaaga ttatttatac
      721 gttttaagaa gtaatgatat gccagctgta cttgtagaat gtgcattttt ggataatgaa
      781 aatgatatga gtttaataaa ctcatctgca aaagtaaaag aaatgggtac acaaataggt
      841 aaaggaatag aagattcatt aaaataaatg gaaataaaaa tatttaaaaa cttaatgtaa
      901 atttatagtt gtaaatttat actaaagtca aaaaatgaaa tataagtgta tcaatagtaa
      961 gactgtatgt acatttgcac gtgtgaatgc aagtatatat acagtctttt tttgtagtta
     1021 aatgcaataa tttgaatgtg ttttgtaaaa tacacaatat gatataatta gataatatac
     1081 acttaattta attgaggaag gtgattatat ggaatattta tttgaaaaaa gtagtttaaa
     1141 agaatatgga aatgaagctt tagataaata tagagaatta ttagataaaa ctggtaataa
     1201 ttcaaggtgt attcttttgt tagtaccaaa caataacaca aagatacgat atgaaaggtc
     1261 tctaagatta aattatagtg aagaactgaa aataacaaca tatataagtt ttgtgaagaa
     1321 agaattagtt aaatactggc cactaataat agaaaaatgt gatgaaataa gtacaaaggt
     1381 tgtatctcca acatttatat caaatagttt aagtgaatat ttaatagtgc aaaaagttaa
     1441 ggaaaaaagg atacaagaag gatattttga agatattaca ggaaccaata aatccatagc
     1501 aaatagtata atgactaaca taaataagtc tgcatttaat ttaattgatt ttgattttat
     1561 tggagaaaaa atatattcat caaagaaaaa taaagatagt atatatagat tttcatacac
     1621 tcaaatggat gaaattatat catattatat aaattcctta ctatcaaatt caattttaga
     1681 taatgcatta agcatatatt tatacaatca atacctactt aatgatgatt tttatttaaa
     1741 aaacttattt acagaagtga gatatataat tgtggatagc cttgaaagct caagtaatgc
     1801 agaagttgat tttataacag aagcattgga taatacatta caaagttata tatattttga
     1861 ttatagtagg gattattctg tatttaataa tgtggatata gactatataa atgagaaaat
     1921 aatatcaaaa attaagccta aagaagaaaa tattaaaaag aaggagatta gaatagaaga
     1981 tttatactta ttacctgcaa atatagaatt aaatcaatca agtcaattat ataatgaaat
     2041 gttagattta ataagtgaaa aagttatatc tcttatagaa gaagatgtat ctccaagaga
     2101 tatagcaatt atatctccta taaacaatag tatattggag catcaaatta gagattcttt
     2161 gatagaaaaa aatatagatg tttttagtac taagaaggat aaaaaagctg tggattatcc
     2221 atatgggaat gcattggtag tggctacatg tatattttat ggatatttag attttataaa
     2281 agatgatgaa tacttaagct ttttagaaac tcttttagaa ataaatagga taaaagcatt
     2341 taagattttt aatgaaacaa gacatttaag tattgataat atagatgaac atagtcagta
     2401 tcgtgagatt ttacagtata ttgaagaaaa aaagaagagt gatataaaaa tacatgaatt
     2461 tttaactcaa ttttacatag ataaaatgtt aaatttaaaa gaaggtaaaa agaatgttgg
     2521 gttatgtaaa aagataatag ctgaaagtga gtcttttagt gaaagtttaa gtctacttgg
     2581 gatgaaaaaa gaaaagatat ttatagaagc tttaaaaagt acaataaacg attattactc
     2641 tgttgtcgat atagaagagt tgaaatccaa agacaaaata gtaataacta ctccttattc
     2701 atatatatca tcaaatatag atagaagtat acaaatatgg gtagatatag gaagtaatgc
     2761 ttggaatatg aaaatagaaa aagatataag taatttaatt gtacttagaa aatcttttga
     2821 agaaaaaaag atttatacaa atgaaatgga agaatattat aaaaaatact atctatacaa
     2881 tacagtatat aatttgttat taaatgcaaa gaaaatctat gcatttaaaa gtgaatatgc
     2941 gattaatggt tatatccaag agagtatatt atatagtata cttttaaaaa tctcacataa
     3001 aggagataaa aattatgatt aatataaatt atagagaaga ccagatacca ataataaatt
     3061 acgataatgg tactatggca gtaccagcag taccaggtgc tggaaaaaca tttataataa
     3121 caaatttagt agctaaacta ttacttgagc agaaacataa gggtggtaaa atattaattc
     3181 ttacatatat gaatagtgct gtaaataatt ttaaaggtag aataagaaaa attcttgaag
     3241 agaataaaat agatgatact aattcgtatg aagtaatgac tatacacagt ttggctgtaa
     3301 aaataataaa ggaaaagcca gaagttgtaa tgttaagtga ggattttaac atagctgacg
     3361 atttgcaaaa aagtattata ttaaatgaat gtataagtag atttagattt gaaggtggag
     3421 aaagagcttt tagatggttt ttaaaggagc aaaaagatga acgctggaaa gaaataactc
     3481 ttgaagcctg ggaaagaggt ttttttgaat ttgcaggaaa tgcaataagt gaacttaagt
     3541 ataagggaat ttctccagat aaccttgaag aaatattgtc aagaggacac aaaggaatgc
     3601 ttaaaattat tttaccaata tataaattgt atgatagaaa attaaagcaa aatggattgc
     3661 tagattatga tgatatatta attttagcag aaaaaacttt aagcttagac gaagggctta
     3721 gaaagaagtt tcaaactaga tacaaatata tatttgaaga tgagtgtcag gactcaaatg
     3781 aaattcaagg taatataata aaaattatat ctagcgaaaa taaaaaccta gttagagttg
     3841 gagatataaa tcagagtata acaggaacat tttcatcatc agaccctaaa ttttttaaag
     3901 aatttataaa tagtgcagat ttctgttata ggatggatat gtcaaatcga agttcaaaag
     3961 atatacttga tttagcaaac actcttgtca agtatgttac aaaggaattt agacagaaag
     4021 aatgtagaca tgctcttgaa gatatgcaaa taaaaactgt gccaaatgga atgggatata
     4081 aagaaaatcc taatccagaa cattataata taaatgtaaa gtggtatgag agttggaaaa
     4141 ttgaaataga gcaaactgct agatatgtta aaggtataaa aaataaatat ccagataaaa
     4201 gtataggtat attggttcca tttaatgaac aagtgacaca agttgctaaa gaacttagag
     4261 agaataatct aacttttgaa gaattaggac caaattcttt gaataaaagg aaggttataa
     4321 acaacatagc atatattatt gattttatgt tacattgtga tgatgtagaa aagttaatag
     4381 ttgtacttaa taaagttttt atagatactg ataatgaaga agaaataaag tattttttag
     4441 aagaattaaa aaactattct actgaagaaa ttatttataa ttttgaattt agtaagttag
     4501 ataatgattt aatagaattt aaagaagaaa gtgacatata tttaagtttt aaaagaggaa
     4561 tagatattat aaaacagata ttagaatatc caataataag gttagacctc ttagttttgt
     4621 ttattgggaa aaaacttaat ttagaaaaag aagataaagc tgtactggat tatatatctt
     4681 tttatataaa gtatctagta tcagaaaata taaatatgga tttagaagat gtatataatt
     4741 tattgtttga tgtaaagaac agggtgttta atcatataat agatgtggta tatgagataa
     4801 atggatatga accagagccc ggtagtataa cactatgtaa ctatcataaa tcaaagggga
     4861 tggaatggga ttgtgtgttt ttactaggtc ttgttgaata taatttccct gacaatatta
     4921 atcaaaagtt tcagagtgat aaatggtatc taaaagaaaa atataaaaac cctatggcaa
     4981 ttattaaatc agaagttgaa gctatattaa aaggaagtat ttcaacagat tatgctcata
     5041 aaacgaagat tgattctata aatgaaaaga ttagactttt atatgtaggg attactagag
     5101 caaaggaaat gttagtactt tcaggaagtg cttatagaga tgaaagtgat atagggaata
     5161 agagaaaaga gcaaaaacca tgtatatatt taagcagact taatcaacat attattgaaa
     5221 aaaggtcaaa ttaatatata ataagttatt aaaagattgc ttgaaatata tctaaaaggg
     5281 gataaaacaa tatgtacagt aagtaactac taaaaaataa agttaagaga gaagtgatat
     5341 gagtgaacga taaattaaaa tatttttctt atagtcaaaa ttcaattaac acatataaat
     5401 catgtccatt gaaatttaaa tataaatata ttgatagaat aaattggaaa aatgatgatg
     5461 ttggtagtag agagtattat gaaactttaa aaacaggaag agattttcat ttgatttgtg
     5521 aaagatattt tagcaatata cctcttggaa tctattttaa tgaggatgat aaaaatagta
     5581 aaaagttttt aaagtggatg gaaaatataa aaaaagttgt tcctattgaa aaaggaaaaa
     5641 cgtatttgcc agaatatgaa gtaaggatga cattaaatgg ggatataata caggcaaagt
     5701 atgatttagt tgtaattgga aataacaata tagaaatatg ggattggaaa accgagtcta
     5761 aaaagattga ctataaacac gtagaaaata gaatacaaac tattgtttat atgtttttag
     5821 caaaagaagt aatacctaaa gttttaaaaa tggacataaa tgttaaagat ataaatatga
     5881 gatattatca acctgaattt gatgacttac caattaccat tttatatgat gaagaaaaac
     5941 atgaagcaaa tagaaataaa attcaaaatt atataagtat gataaaaaac actaattatg
     6001 aagaacatac atacgaagac aatctataca atgatataga aaaggtatat aataaagaag
     6061 aacgtatgtg ctatagaaat aaaaagcatt gcaagtattg tgaatttaat aagttatgta
     6121 atggcaaaga aatagattat agtattttgg aggcggaaat ttatgggact taggtttgta
     6181 ttaggtagaa gtggaagtgg aaaatccacc tatatactag atgaaattaa aaaagaagct
     6241 caaaaaaatg aaacgacatc aattatactt ttagttccag aacagtacac atttgaggct
     6301 gaaaatagag taagtaaact atttttagga aaagaaaaag ataagtatct aagagttagg
     6361 gtacttagct ttaagacact aagtaatata gttttttctc aagtaggagg attgacagat
     6421 gtaaatataa attctagtgg aaaagcaatg atggtatata gagctattga agatgtaagt
     6481 gaagaattaa atgtgttttc aaaatcaaaa tcgcagtctg gttttgtaag ttcaattaca
     6541 gatatgatat cagaaatgaa acaatacaat ataagccctg aaatgttaga aaatatatct
     6601 ggagaattgg ataatgaaac tttaagttta aaattaaaag atataagtaa aatatataat
     6661 tcttttgaag ggaaattgca tgaaaattat gtagatgctc aagatatgtt aacttcattg
     6721 gcaagtaaaa ttgaattaag cagttattta gatggagctt gtgtttatat agatgaattt
     6781 acaggtttta caccaaatca gtacaatgtc ataaagagta tattaaataa gtctaaaagt
     6841 gttaatatct ctttgactgt agatgatatc aactatattg ggtacagtaa atctgatatg
     6901 ttttctagaa cgaaatttac ttattcaaaa ttgactcaat tgtgcaacga agaaggcata
     6961 aaaatattgc cacaagtaaa tttaaacaca ggtgttataa aaagatttga aaaagttaag
     7021 gaattacagc acttagaaag attttataat gcttatccat ataaaatata ttcaaatcca
     7081 actgaaaata taaagataaa agagtttaac aatttatatt cagaggtgga agagatagcc
     7141 agagaaattg tacatttagt tagagataag aatgtcagat atagagatat aaccattgct
     7201 acaagagatt taaatagata tgatttttta gtacactcta tatttaatga atataatata
     7261 ccaaacttta tagataagaa gagagaggca aaaagtaatc caatagttat tttaattatt
     7321 tcagctttag aaatgaagaa tagacgatat gggtatgaaa ctatgtttag gtatttaaaa
     7381 agtggactta taggaattga taatgatgat ataaatttac tagaaaatta tgtgttggct
     7441 aatgggatta aaggtaaaaa atggtttgat gaaaaatggg attatagaat aacccaaagt
     7501 ctttcaggtc aagaaagtga atttgaactg gaattaaaag agaaaataaa tgaaataaaa
     7561 aatagagtat tagagcctat agtaatttta caagaaaaat taagaggaaa aaatagagta
     7621 aaagaaatct gtagatatat atatgaattt ttattagata taaatatgcc agaaactata
     7681 gaaagtttaa tagtaaattt taaggataaa ggggaacttg atgttgcaaa tcaatactca
     7741 caagtttggg acatagtagt ggacatatta gaccaaatgg tggaacttat gggtgatgaa
     7801 ataatttctt tagaaaaatt tataaaatta ataaccttag gttttgatga atatgaatta
     7861 ggactggttc ctcctagtat agaccaggta cttgtaagta gtgtggatag aatgaaaaat
     7921 ccagacacga aatatttata cctagttgga actactgatg gtgtgtttcc gctgattaca
     7981 aaggatagtg gaatattgag tgataatgat agggaaagtc ttggaaacaa aggaatcgaa
     8041 gttgatattg atagtaagac taggagtttt gaagaacagt ttcttgtata taaagctctt
     8101 acttcgacat ctaagaattt aaccataaca tatccaatat cagaccatga aggtaaaacg
     8161 cttagaccat caataattat atcaagactt aagaagatat ttccaaatat agaaaataaa
     8221 agttatttag tggaagaaaa taaaagcact gataaagata tacttaaaaa aataacggtt
     8281 aaatccccta catttaatga acttataaac gtaataaaaa attatgacag tgatggttac
     8341 aatacagaag agattaatag tatttggtta gatatatata ggtactattt aaaagatgaa
     8401 atctatagtt ctataacaaa aaaagttata aaaggtctta gttatactaa tcaagttcat
     8461 aagattgaag agaaaaaaat aaggtcattg tataaaagta attctcttag catatctagg
     8521 cttgaaaaat atgctgaatg tccatttgct tactttatac aatatggtct aaaagcaaaa
     8581 aagcgtaaag agtattcatt tacaccacca gatttaggaa cttttattca taatatttta
     8641 gataggtttt caaaagaact tttacaagat aatttaactt ggagagatat tgatgaaaaa
     8701 tatatagaat taaagatagg tataatagtt gatgaaataa ttttaaagat accaggatat
     8761 atattaaata gttctgagag gtataaatac cttgcatata gattaaagaa tatgttgaca
     8821 actgctataa ctataattag tcagcaaata aaacaaggtt catttgaacc aatagattat
     8881 gaagttaaat ttggcaacaa tggaaaatat ccacctataa aaatggtgtt agaaaatgga
     8941 caagaagtaa gtttaattgg acaaatagat agagttgatg aatttgaaga aggagaaaat
     9001 aaatatataa gaataataga ttataagtca ggcaataagt ccataagtct aacagaaata
     9061 tattatggtc tacaattaca attacttgtg tatttagatg caatccttga aagtgcaaag
     9121 gatgaagata taaatataaa tccagctgca atactatatt gtagaataaa taatccaata
     9181 gcaaaattta atgaagataa agatgatgaa gaaatacaag aagcaatatt aaaagaactt
     9241 agaatgaagg ggcttgtagt aaaagactct cacatagtta aagagatgga taaatcatta
     9301 atagatggag aaaggaaaaa ctctttagta ataccagtag gtcttactaa ggatggaaat
     9361 gtaggtaaaa gtacttcagc aataagctat gaggatttca aactgcttag aaaatatgta
     9421 aggcatgcta taaaggattt atgtgaagaa atgttaagtg gagaaatacg tatagctcca
     9481 tataaacata aagatggaac atcatgtgac ttttgtgatt actctgctat atgtcagttt
     9541 gattcaacta taaaagataa caagtataaa aatttaaata ataagagtaa tgaagagata
     9601 ataaaaatga tgaaaggaga tgttaattag tgagttctcc taaatggaca aaagagcaat
     9661 tagaagttat agaaagtaga gaatgcaatt tattggttgc tgctgctgct ggttcaggaa
     9721 aaacagccgt tctagttgag cgtataattc aaatgataac aagtagagaa aatccaattg
     9781 atatagataa gttattagtt gttacattta ctaatgctgc tgcgtcagaa atgagagaga
     9841 ggatagggga tgctatagga aaagccttag atgaaaaccc agaaaataaa catttacaaa
     9901 accaacttgt tttattaaat aaatctagta ttacaacaat acactcattc tgtttggatg
     9961 ttataaaatc aaactttcat agaataaact tagaccctaa tttcagaata ggagaccaaa
    10021 ctgaatgtgc tattttgaaa caagaagcaa tagaggaagt atttgaagat ttatatgaag
    10081 aaagagatga ggggttttta aatttagttg aaagttatgc agaaagagga ggagataaag
    10141 aagtacaaga tattatcttg ggaatatatt catttgcaat ggcttctcct gaacctaaaa
    10201 aatggttgat tgactcagca gaacgattta atattgatga aaattttgat ttttcacagt
    10261 ctatttgggc tagagctata ttagacactg taaaaataga gattaatggt ctttgtctaa
    10321 atatggaaag ggcattaaaa gaagtggaat caatagaaga attagaaact tttgcagaaa
    10381 agttatccgt tgaatataaa aaaattgctg acatttcaca agcatgtaat aaatcttggg
    10441 atgaggcata taaaaagatg gcaagtatgt cctttgaaaa ttatgtaaaa ggagtaaaaa
    10501 gaatttcaaa agatgctcct tcgtatataa aagaatcaaa agaaaaggca aaaactataa
    10561 gagataagac taagaagtct ttagaaagta tagtaagtgc tacattcaat aaagataatg
    10621 attctattag agaagaaata aaatatcttt ataacatagt taaaccaata tctagtgttg
    10681 tactgagatt tgaagaggaa tatagcaata agaaaagaga aaaaggaata atagatttta
    10741 acgatataga gcattttgca ttaaatatac ttacagatgt agatgaaaaa ggtaatattg
    10801 taccttctga tatagcagtt ggatgtagaa acaagtttta tgaaatattt atagatgaat
    10861 atcaggatag taatctagtg caggaagtac tgcttaaagc tgttgcaaat acagaaactc
    10921 caaatagatt tatggttggt gatgtaaaac agagtatata tagatttaga caagcaaagc
    10981 cagaattatt tttgcaaaaa tataataact ataatgataa aaagggaagc tcccatagaa
    11041 aaataatgct ttacaaaaac tttagaagta gagaagaagt tgtagatgct gtaaattata
    11101 tatttgaaaa tataatgaat gagaatatag gagaaattga atatacagaa aaagaaagac
    11161 taaatttagg tgcaaatttt aatgtggata cagacgagaa atctattatt ggtggagcaa
    11221 cggagataca cctaatacaa aaagataata aacttgatga tgatattata aatgataaag
    11281 acgatagaat taataacaaa gaaaatgaaa tagaggaaga agaaaaatta gataatatac
    11341 aacttgaggc tagaatggtt ggaaacatta tcaaagattt aatgaaagtc aatgaagatg
    11401 gaaaaattca aaaggtctat gataagggaa tagatggata tagacctgtg gaatttagag
    11461 atatagttat tcttttaaga gctacatctg catgggctcc agtgtttgca gatgaattga
    11521 tgaatatgga tataccaacg tatgctgatg ttggagtggg gtattttgat acgattgaaa
    11581 taaaaacaat attgtcatta cttcaaataa tagataatcc aatgcaagat atacctctta
    11641 tatctgtatt aaaatcacct atatttggat ttacaccaga ggatttgatt gatattagag
    11701 ttcagagtaa agataaaatt ttttatgagg ttttaaaaag tacagcagag tatgatggat
    11761 ttacagattc tcaaaatgaa aatgagtctg agtttatacc aagtgaagag tgcataaaca
    11821 aaagtaaaga ttttttaatt aagctaaagg aatttaaaga aaagtcaatg tacatgagta
    11881 cagatgaatt tatatggtac ttgtacacaa ggactggata ctatgcctat gttggagcat
    11941 tgccaggtgg aagtcaaaga caagctaatt taaaagtatt gtttgagaga gcaaaacaat
    12001 ttgaagaaac cagtcttaaa ggaatattca actttgtaaa ttttatagag aaattaaaaa
    12061 aatctagttc tgatatggga agtgcaaaaa cacttggtga gaatgcaaat gttgttagaa
    12121 taatgagtat tcataaaagt aaaggtctag aatttccagt agtcatatgc tctgcaatgg
    12181 gtaaaaattt caatactcaa gattttaaaa agagtatttt atatcatcat aatttagggt
    12241 atggacctca atttgtagac tatgagagaa ggatttcttt tccaagtata gccaaagaag
    12301 cattaaaaag caaaataaat atagaaaatt tatcagaaga gatgagagtt ttatatgttg
    12361 catttacaag agctaaagaa aaattgatta taactggttc tactagaaat atacaagata
    12421 gtataaagag atggtcaaat ggaattgaaa gtttagatac aatatcacaa tacgagatat
    12481 taaaaggtaa aaatttttta gattggataa tgccttgtgt attaagacat agggatttat
    12541 ctaatctact agaagaagta ggattagacg cagtttttaa tgttgaacat aattcaaaat
    12601 ggtatggaaa gttgtggaat aagaatgata ttttagtgga aaagaagagt gatgaagaaa
    12661 aagaaagtat tgaagaaatt cttgaaaaaa tagatgtaaa taatcctgac agtgattatt
    12721 acggtgaaat agaagaaaaa ttaaactata tatatccata tgaatttagt acaagaaaac
    12781 ctgctactat atctgttaca gaaataaaaa agatacaaaa taattatgaa gaagagttaa
    12841 taaatactat atttgaacaa aaagtaatat taaaaaagcc tctatttatt caaaatgaag
    12901 aagaaagaga aaaaataagt ggaacagaaa gaggtacaat agtccattta gttatggagg
    12961 ttttagactt aaaaaatgta agtagtgtaa atgatataaa atcacaaata agaggttttg
    13021 tttcaaaagg tataataaca gaaaaacaag ctagtatagt aaatccatat aaaatatata
    13081 aattttttgc ctctaacata ggaaaaagaa tgttgaatgc tgaaattata aatagagaaa
    13141 aatcaattta tgcacaagta aatatgaaag acatatatat ttatgaaaag cttataaaca
    13201 atgacgataa aaaactttat gataatgaaa gtgtcatgtt aagaggtata gttgatgctt
    13261 attttgaaga agataatcaa atagttttgg tggattataa aacagatttt gtaaatgagg
    13321 aaaatataaa tcaaataata gagaaatata aaaaacagtt ggatttatat gcagatatta
    13381 ttgaaacttt aactggtaag tcagtaaaag agaaatgtat atatttattt ggagttgatg
    13441 aagctgtttg ttattagttt ttatatataa attaaaccta aaagatagag gaaggggaaa
    13501 aaatgagatt tattcataca tcagattggc atctagggaa gtccctagaa ggccattcta
    13561 gaattgagga acaagcaaag ttttgtgagg aatttataaa aatagtagaa tcaaatgaaa
    13621 tagatatggt tataattgct ggagatgtat atgatacttc taatccccca gcacaagcag
    13681 aaaaactatt ttatcagact gtatcaagac ttgccaataa tggtcagagg tgtgtattaa
    13741 taatttcagg aaatcatgat aatccagaga gactctctgc aataacacct ctagcacatg
    13801 aacaggggat acttatatat ggttatccat taagtgctac gatagaagct aagtataaag
    13861 ggtttgaaat aacatatgca actcagggat gtacaaaact gaatataaat ggagaaaata
    13921 ttgtggttgc tacattacct tatccaagtg aaaaaagatt aaatgaagtt ttttcaagtg
    13981 aagatgagtt tgagaaacaa aaaaattatt ctgaaaaggt aggagatata tttagaagtt
    14041 tagaagaaaa ttttagaagt gatactataa atatagccgt atcacatata tttgtaatag
    14101 gtggagagag tactgaatca gaaagaccta tacagttagg tggaagtttt ttagttgaaa
    14161 gaaaagattt gccagaaaag gctcaatata ctgcactagg tcatttacat aaacaacaaa
    14221 aagcttccga acgtttaaat gcatactatt ctggttctcc acttcaatat agcaaggatg
    14281 agagagcgta taccaaaggg gcatacatag tggatataaa agctggtgaa aaaccaataa
    14341 ttgaagatgt atattttaat aattacaaac ctatagaagt atttaaatgt aatggaatag
    14401 aagaagcact agatatatgt gagcaaaatc aagatagaga gatttggtca tattttgaaa
    14461 taaatactga tgagataata tcacagaatg aaattaaaaa aatgaaggaa ctattaaaag
    14521 acataataga aataaaacca ataataacat cttgttatga acaagaaagt gtagatataa
    14581 aagaaaagtc tatggcagag ttgtttagag agttctattc ttttagtaaa ggtgtagagc
    14641 caaaaggaga acttatggat ttatttctag atataataag tgaagaaggt gaatcagcag
    14701 atgagaccaa ttagattaga acttacaggg cttaatagct atattgataa acaagttata
    14761 gactttgaaa aattaattga aagaggtttg tttgggatat ttggaactac tggaagtgga
    14821 aaatctacaa tcttagatgc aataactatt gctatgtatg gaaatatatc cagaaataca
    14881 aaagaatata taaacagtgt gtgcgataag gcaattatat catacgagtt tgagatagga
    14941 agcaaaaaca ctagaagaag atacattgta gatagaacca ttgctagaag caaaacagga
    15001 acaaagacct ctaatgctag attaatagaa gtattgaatg acaataccca aaatgtttta
    15061 gctgataaag ttgtggaagt aaatgaaaaa gtagcacagg ttgtaggatt aacagcaaat
    15121 gattttacta ggtcagtagt tttaccacaa gacaaattta atgagtttct aagattatca
    15181 cgtgcagata gaagagacat gttagagaga atttttaatc ttgagaaata tggaagaagt
    15241 cttggagaaa aagtgaaaaa gagaaaaaat atacagttac aaaatttaaa agatttgaaa
    15301 tcaaaattaa gtcaatatga tggaattaca gaggaagtat acaacaatat aaaccaagaa
    15361 ttaatagagt taaaaaattt ggaaaaagat aaggataatg ctttagacct agctcaaaaa
    15421 tcttatgaag aaagtaaaac agtatatgaa gaacaattaa agttagaaaa aaatgaactt
    15481 agaaaaaatg agcttgattt aaaaaatagt gagataaaag aaaagattgc tcttgtagaa
    15541 aatgatagta acgctaaaaa ggtagaccca tacataagtt cagttcaaaa tctagaaaaa
    15601 aagatagatg aagatagctt cgcagtaagt aatttagaaa agaaattagc aatattaaat
    15661 caggagcttg aagttacaaa aaatagatat gaaaaaataa acaaaattaa gaatgaagaa
    15721 gtccctaaat tgagtgaaga aaaaataaga ttgcaacaag caataaaatt agaagaagag
    15781 ttagttttat tagatagaga gttaaaagag ctaaaagaaa gtggaattaa tttaaataag
    15841 actaaagttg aattagaaaa agtaaagcag gtgtcagagt ccagaaaaga tgcagttact
    15901 aaatctataa aagaagttga aggaaagatt gataaagtaa atataagtgc agaattaaaa
    15961 caaaaaatat ttctagcata tgaatacgag aaagattaca acaacgtatt ggaagaaaaa
    16021 aatcaaaagc taaataaact agaagaaata ctcaaagaga cagaaaatat aaatttaaaa
    16081 gttagatata ttgataaaga taagaatgat gtaaatcgta atttagaaaa tttatcactt
    16141 cacttggatg ttcttcttaa aaaatgtcct ggtaagagtg ctgatttact tttaaaatct
    16201 gaatatgtta ctgaattaag aaataaagca aataatacta aagaaaatga aattaagaaa
    16261 agcagtatac aagatgaatt aaagataata cttgaaagta agtttaatac tgaaagggaa
    16321 gtaaatttac taaatgaaaa acttgaaaat aatagaaaga acagagatga cttagaaaaa
    16381 gaattagaag aactaaagta tttaaattta gcctctgaac ttagacgtga attaaaagaa
    16441 aatatgcctt gtccagtttg tgggtcaaaa catcatgaaa atcatgatat aactaagtat
    16501 gatgaaaata tatcttttgt caaagaaaaa ctggagaaat tagaaaaaga aaaaataagt
    16561 ataagaaaca atatagagga attaaatgct aaagtaagtg ggtatttatc tatagaaaaa
    16621 atgaagacta aagaacttga agatgtaaaa ggaaaactag gggggattcc atctagtcaa
    16681 ttattaaaaa aacttgatga agaacaaaga aaacttgcat tgttaaaatc taatattcag
    16741 gagtgggaga aagaaaaaga gagtactgaa aataaagtaa cattagctaa agaagaaaaa
    16801 aataaaattg aaaaagaaga attaaaaata agagagagtc tgaataatta taagaaatta
    16861 acaagagatt taaacataga aatagaaggt ttagaaaata aatgtaaaaa acttaaacag
    16921 gaatacctag gattaaagac gattactaaa gtctctaatc tattgtcaaa agtaaaagaa
    16981 ataagagaga atgaaaaaga attagaatta ctaagtactg ggcattcaaa tttattaaaa
    17041 aatagagact cactagatat taaaataaga gaaaatgaga gtaaactaca tgaaatagag
    17101 atagaattaa taaaggctag agaattatat gtagaaaaga aattgagtag agataataag
    17161 tataaagaag ttattagcat aacgaaaggt gatttagcta aaaatctttt acataatgtt
    17221 gaagaaaata tatgtaagat attagaacaa gaagaatcaa gtaagaaaaa attggaagag
    17281 caaagattag aatatgaaaa aaacattgct gaaaagcaca atatagatgg tagacttaaa
    17341 actgctaagg aacaatataa agaccaaaaa tcaacactaa ataaactatt agcagaaaat
    17401 aaatttgaaa gtatatatgc agtaaaaaga gctttattag atactgatgc agtaaaaaaa
    17461 ttgattgaag aaatactaga gcatgaagaa gaacaaaagt tattatcatt taaaataaaa
    17521 tcatcaaaag aaaaattaaa tggaagaagc ataaagaagg agtactttga acagttaaaa
    17581 gatgaaattt ataatttgaa agtagaaata ggaaatatat ccaaagatat tggagctaat
    17641 caaaatcagt taataacatt aaaagactct ttagataaga taaatgattt taataaacaa
    17701 cttaaggtag ttgaacacaa tgtggactta ttggaagaat tagataaatg tgtacaagga
    17761 aataaatttg tagaatatgt ttctacaaac caattaaaat atatagcgtt ggaagcatca
    17821 aaacgattgg atggaataac aaaaggaaga tatgcacttg aaattgactc aacactaaac
    17881 tttgtaatga gagataactt taatggagga gaaagaagaa gcattgatac tctatctggt
    17941 ggagagacat tcttgacatc tctatcatta gcacttgctc tttcatctca aatacaatta
    18001 aagggaagtg caccattaga atttttcttt ttagatgaag gttttggttc attagatagt
    18061 gaacttttag aaattgttat agaatcattg gaaagattgc atagtaataa tctaagtgtg
    18121 ggtataataa gtcatgtcga ggaacttaaa aatagagttc ctgttaagct attagtttca
    18181 tctagtgagg ctggaatagg ttcaaaagta aaaattgaat atagttagaa aatatatgtt
    18241 aat
//
LOCUS       DAYAKB010000073        18240 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.073, whole genome shotgun sequence.
ACCESSION   DAYAKB010000073 DAYAKB010000000
VERSION     DAYAKB010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18240
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.073"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            162..551
                     /locus_tag="ACGI3L_002909"
     CDS             162..551
                     /locus_tag="ACGI3L_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9198606.1"
                     /translation="MKQQEVVNKLRRGELMLMEYLWRKNSILSKKEIIEAMKEKYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNAIKEDRKVTKYDSFFIRMF
                     TTMHKKEKMTEEQIKKYIENMEKIGKE"
     gene            645..1028
                     /locus_tag="ACGI3L_002910"
     CDS             645..1028
                     /locus_tag="ACGI3L_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9198607.1"
                     /translation="MGFKKLPDSELKVMKFIWGLDGNKVASGEVVEAMKQIYDWNKNT
                     TLTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTAL
                     NDEENLSDDKLDMLEEWVKNWEEDE"
     gene            1746..3137
                     /locus_tag="ACGI3L_002911"
     CDS             1746..3137
                     /locus_tag="ACGI3L_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9198608.1"
                     /translation="MRNKIIIGITFLLVLLMSGCASKQTAEINVLATTDLHGVIPYEL
                     TSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGDNNTESYIETPISK
                     DMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTYKKNGDSYTKPYII
                     KNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQEGYNGELYMNDLVE
                     DAKKWVSIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVDGIDAIVAGHNHVQ
                     IEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDKSSKLIKFEKNQES
                     DKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDIYKTIGYKWRNISS
                     PKSDGMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKDNVVTIYPNKNDKFKIEK
                     GKQEYSINLKHIQ"
     gene            complement(3285..3593)
                     /locus_tag="ACGI3L_002912"
     CDS             complement(3285..3593)
                     /locus_tag="ACGI3L_002912"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9198609.1"
                     /translation="MLREQGSAIRDTLDSVLSLSNQKAYPVWESVNSFALIKAAQAGL
                     GITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNITQPLKIILDNISNVL
                     "
     gene            3630..4151
                     /locus_tag="ACGI3L_002913"
     CDS             3630..4151
                     /locus_tag="ACGI3L_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HFG9198610.1"
                     /translation="MFSIGGGYAIIPLIQEKVVNQTGWISEKIFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIMSGILGIFFYL"
     gene            complement(4280..4516)
                     /locus_tag="ACGI3L_002914"
     CDS             complement(4280..4516)
                     /locus_tag="ACGI3L_002914"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198611.1"
                     /translation="MLECFIAKDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSKKFCQEAYDWFVENQ"
     gene            complement(4826..8254)
                     /gene="uvrA"
                     /locus_tag="ACGI3L_002915"
     CDS             complement(4826..8254)
                     /gene="uvrA"
                     /locus_tag="ACGI3L_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFG9198612.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEALNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNHLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQAPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            8573..10807
                     /locus_tag="ACGI3L_002916"
     CDS             8573..10807
                     /locus_tag="ACGI3L_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9198613.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            11063..13093
                     /locus_tag="ACGI3L_002917"
     CDS             11063..13093
                     /locus_tag="ACGI3L_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9198614.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            13090..13542
                     /locus_tag="ACGI3L_002918"
     CDS             13090..13542
                     /locus_tag="ACGI3L_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9198615.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            13544..14599
                     /locus_tag="ACGI3L_002919"
     CDS             13544..14599
                     /locus_tag="ACGI3L_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HFG9198616.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            14666..14974
                     /locus_tag="ACGI3L_002920"
     CDS             14666..14974
                     /locus_tag="ACGI3L_002920"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HFG9198617.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            15078..16343
                     /locus_tag="ACGI3L_002921"
     CDS             15078..16343
                     /locus_tag="ACGI3L_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HFG9198618.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            16431..17147
                     /locus_tag="ACGI3L_002922"
     CDS             16431..17147
                     /locus_tag="ACGI3L_002922"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9198619.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHELEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(17342..17635)
                     /locus_tag="ACGI3L_002923"
     CDS             complement(17342..17635)
                     /locus_tag="ACGI3L_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HFG9198620.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(17641..17856)
                     /locus_tag="ACGI3L_002924"
     CDS             complement(17641..17856)
                     /locus_tag="ACGI3L_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198621.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
BASE COUNT         6804 a         2080 c         2967 g         6389 t
ORIGIN      
        1 aattatttga aaatttaata attttataga tatgaaagtt attttcttct aagaaaacag
       61 actaaatgcg tagaatattt ggtaaaactt acctgtataa attgaaatca gaaggtttta
      121 ttattgattt agattagaac aatttgaggg agtgacataa aatgaaacaa caagaagtag
      181 ttaataaact acgcagggga gaattgatgt tgatggaata cttgtggagg aaaaattcta
      241 ttttatctaa aaaagaaata atagaagcaa tgaaagaaaa atataagtgg aggaaaagta
      301 ctacagaaat tctattaaaa agattagtaa aaatgaaaac attaaaaaag aagaggatag
      361 gttttcagtt tagttatgaa gtgctagtaa ctaaaaaaga atatttaaat gcaataaaag
      421 aagatagaaa ggtaactaaa tatgatagtt tttttatacg aatgtttacc actatgcata
      481 aaaaagaaaa gatgacagaa gaacaaataa aaaaatatat agaaaatatg gaaaaaattg
      541 gaaaagaata atttatatat atattaatta tttttaaaat aaatttgtta taatatttaa
      601 atatacataa acatacataa atttacaaaa agggggtgta gcttatggga ttcaagaaat
      661 tgccagattc tgagttaaaa gtaatgaagt ttatttgggg attagatgga aataaggtag
      721 catcaggaga agttgtggaa gcaatgaaac aaatttatga ctggaataaa aatacgacat
      781 taacaatatt gtctaagctt gcaaagaaaa actatttgta ttctcaaaaa acaagcaagt
      841 gtacatatta tactatcgct gtaagagaaa aagattattt aaaagttgaa acaaaaaaat
      901 tctttagttt ttttcataat aattctttaa aaagtttttt cactgcttta aatgatgaag
      961 aaaatttaag tgatgataaa ttagatatgt tagaggaatg ggtgaaaaat tgggaagaag
     1021 atgaataaaa tgaatgtgat actaaaatga tactaatatg ttttatagcg tgttaaaaaa
     1081 tatagaaaat atagaaataa tagaagaaaa ttaatgtaat agataaggtt ttatcagatt
     1141 aaaaagaaaa tcaatagaat gggaataaaa tatagaatgc caaaaatcca cataaataca
     1201 ggatttaagg tctctcttac ttctatgtta tactggtttg atactatcaa tatttgccag
     1261 tatcttatgg attaataagt aaaaaacatc ctgctgaatg ataaattcag cggggtgttt
     1321 ttattttgtt ttagaactcc tttgctctga aactcgaagt atttaacact gatgattttg
     1381 ttatctttta gttccttttg tgtcatgctc tgaaagacaa attgatacaa taaaaaagta
     1441 atttcttaat cattgatgga gatatgtatt tatgttactc ttgatggtaa tttgagtaat
     1501 attgttcata gctttttata ttcaattaat tagaaaacca tttggtataa tcataaataa
     1561 acttgatgat ataatagaaa agatttataa ttattagaag tatataaaag tattttatgt
     1621 ctatgaaatg tatgtctata aaacatatag atgacttttg tatattaatg tatgaatatt
     1681 gatattatag aagaattgag ttgtcaatga tactaaatca aatatttata gaagctggag
     1741 ggattatgag aaataaaata attataggaa ttactttttt acttgtatta ctaatgtctg
     1801 gatgtgcttc aaaacaaacc gcagaaataa acgtattagc aactactgat ttacatggag
     1861 ttatacctta tgagttaact tcttatgtaa aagaagaaag aaaaaaagat aaaaatctaa
     1921 ctttagtaga tgcaggagat ttttttgata gtggagaagt gtttggttct agcatggata
     1981 gttattttag tgctagatat aaagatggtg ataataacac tgaaagttat attgagacgc
     2041 ctatttcaaa agatatgaaa gaggtaggtt atgatgttgc agttcttggg aatcatgaat
     2101 ttatatccaa caataaattt tatctagata atatgatatc tgattttgag aagcaaaaaa
     2161 taaatatttt atcggcaaat acgtataaaa aaaatggaga cagttataca aaaccataca
     2221 taataaaaaa tattaataca cctgaaggaa acgtaaaact aggaatttta gggcttacta
     2281 taaaagaagt tggtgagagg aaacagtgga aagatggaaa acttgttgac tctaagtctt
     2341 tagaactaaa agaccaagag ggctacaatg gtgaattgta tatgaatgat ttagtagaag
     2401 atgctaaaaa gtgggttagt ataatggaaa aagagaagcc tgacattata gttgctgtgg
     2461 cacatacagg tgagaaacct aagaaaccta aaaacccagg aaatagaata caagacttag
     2521 ctcaacaagt tgatggaatt gatgctatag ttgcaggtca taatcatgtt caaattgagc
     2581 aacatgatta taaaaataaa tcaggagaaa atgttatagt tactgagcca ggaaagcatg
     2641 gggaatgtat ttctaagatt aattttaaat tagaaaaaaa caatgataaa tggaatatag
     2701 ttgacaaatc tagtaaatta attaaatttg aaaaaaatca agaaagtgat aaatttggag
     2761 aatttatttc ttcaattaat aaagtaagta aagataagaa agaaataaga ttatcagaag
     2821 taaagactcc tgaatgggat aaaatatatg tttttaaatc tggaacatct gcagatgata
     2881 tatataaaac aataggatat aaatggagaa atatatcatc tccaaagagt gatggcatgg
     2941 tgcagattgt tgtaatgaat aataataagc ctgttagcta tatatatggt gaagctgaag
     3001 ttatgccaat taatataaaa tgtgatgaat cagagtataa agataatgtt gtaactattt
     3061 atcctaataa aaatgataaa tttaaaattg aaaaaggtaa acaagaatat agtattaatt
     3121 taaaacatat acaatagaaa cttttatctt atttaagttt agattgtact taaaataaag
     3181 tgtgtattat tttaaaaatt gatgataatt aaaatcacaa cattaaggaa tagtacacac
     3241 tttttatgct aaaaaataga atgttaaaaa attaaacctt taaattaaag tacattgctt
     3301 atattatcca atattatctt caaaggttgt gtaatatttt tatccttatg taatattgct
     3361 aacattttat tttccatatc tatcccatct aattcaatca atcgcaattt tttatgtaag
     3421 agtgaatcta ataataaatt ttctggcaaa atggttatac ctaaccctgc ttgtgcagct
     3481 ttaataagtg caaaagaatt aacactttcc caaacaggat aagctttttg gtttgaaaga
     3541 gataatacac tgtccaaagt atcgcgaatg gcacttcctt gctcacgtaa caataacgga
     3601 aacgtgcata actgtcgtag agataaggct tgtttagtat tggtggtggt tatgcaatca
     3661 tacctttaat ccaagagaaa gtagtaaatc aaactggatg gataagtgag aaaatattta
     3721 cagatattat aactatttca caaatgacac cagggccact ggctgttaat acttctactt
     3781 ttgttggact tcaaattgga gggttttggg gagcagttgc agccacttta ggttgtgtat
     3841 tatgtggtgt agtaatatct ctatttttat ataatttttt tcaaaagcat cagaactcta
     3901 cttatatatt tgaaatatta aatggtctaa aatcagcttc attaggttta attatctcag
     3961 ctgcggctac aattataatt cttgcattat ttgggacgaa taaagtgtac ttcaattcta
     4021 tatttgagat gctaaactgg actgcactaa taatcttttt tgttacacta ctgatagtac
     4081 gtaagtggaa aattaatcct attgtgatta taataatgag tggtatactg ggaatatttt
     4141 tttatttata agtttttgct aagtaaagga tatctatttt tttatatctt aaatccaaat
     4201 agccaataaa gtaaggctat ttggattttt aataaattct gaaaagataa tcagaaacct
     4261 atataacatt taaattatat cactggtttt ctacaaacca atcataagct tcttggcaaa
     4321 atttcttact atctatatag taactattat gaacattatt aatttcaaca agtttctttt
     4381 tacattttag tgaattataa tagctatcaa aatattgggt tttaaaatat ctatcatgaa
     4441 gtgttttaaa gacaagagta ggtatgttga ctccatcttt tatcttacta tcttttgcaa
     4501 taaagcattc taacattgta ttaattatct ttgtactatt tttccaaata tgaggatttt
     4561 tcttttcaaa tattttataa aattcattat catagacttc attataacct ttatatttag
     4621 gtggttttac tgttatgtga aaattaggaa gaaacttaaa gaaaaaatat aataattttt
     4681 atgttctgtt ttatatatta ttcatatttt atcacagata atatactaaa gttaattttt
     4741 ttattgtaca actattataa taattcttct ataatataag acattctata attttatatt
     4801 taagttcatg tgtatttaat tgtttttata taaaatgtcc agtaatacta tttggattta
     4861 tttttatttc atcaggagtt ccagaagcaa caatttcccc tccatttatt ccactgtctg
     4921 gacctatatc gataatccaa tcagaagcac gtataacctc tgtattgtgt tcaataatta
     4981 aaagtgaatg ctgttcattt acaagttttc taaaagtaat taacaaattt tctatatctt
     5041 taaaatgaag tccagtagta ggctcatcca atatgtacag cattcgtttt ttagtttttg
     5101 tccctaattc ttttgctaat tttatccttt gagattctcc tccacttaat cctaatgtat
     5161 tttgtccaag ctttagatat ccaagtccca cttcatctaa taaggagagt tttctatata
     5221 tatcagagca atcgctaaaa aatgtttttg cttctgctac ttccatgtca agtatatctg
     5281 caattgtctt tcccttgtat tgtatagaca gtatttcttt ttgatatctc ttaccttgac
     5341 attcactaca agttacccat tggtctgcca tatattgcag aataattttt gttttaccta
     5401 atccttgaca gtttgggcat tgcccctttt tgctattaaa gctaaaatag ctttcatcca
     5461 ataatttttg ttttgcttgt ggagtttcag caaatagaga acgaatttca tcaaaaatat
     5521 tgatatatgt agcaggtgta gaacggctag attttccaat aggtgcttgg tccattaaga
     5581 taaaatcatc aatagcatca aatccagtaa attcagtata atttttatct gggatagatt
     5641 tttgtttcaa tttttcttct agagcaggaa gtaaactgtg aaatacaaga gagctcttac
     5701 cagaaccact aacacctgta atagagcaca tacagtttaa gggaatttct acatcaatat
     5761 tttttaagtt atttgcatgg catcctttta agcttaacca tttacttggt ataattttat
     5821 tttgtgaact tattttattg tatgtactta aatatttacc tgttatagag tttggatttt
     5881 ttataatttc ttgggttgta ccttctgcga taatgaaccc cccttttgta ccagcacttg
     5941 ggcctacatc aataatataa tcagcagaca gtattgtatc tttatcgtgt tccacaacta
     6001 taacagtatt acccttatct cttagctctt ctatcatttt gatgattaaa ttatggtctc
     6061 ttgggtgtaa accaatagat ggttcatcta aaatgtaggt taagcctact aattcacttc
     6121 ctagctgact tgataatcgt actctctgca gttctcctcc agataaagtt ggagctgttc
     6181 tatctgttga tatatagcta agacctacct ttaatagata actaactcga atttttaatt
     6241 ctgttaagat atcatttacc aaagagagct catttttttg aaggtgattt ggtaattcac
     6301 acaaccaatt ccataactgt tctatcgtca tttttgttag ttcagggaag cgataacctt
     6361 tgattgtagt gaatctagcc tcaatgcaca gcaattcgcc accacatgta ttgcaaggaa
     6421 ttttgttcat atattgatgc aaggtattat tttcagaact agattctcta aaaagtcttt
     6481 gaatgtggtt gattgctcct gaagcaggtc ttctaatctt tgattctcgt ccctttgatt
     6541 caaagctaaa ttcatatatc ttatcgtctg taccatataa gattgcatct ataaaatctc
     6601 ttggtaattc attccaaggt atatctaggt ctatattttt atcttttgct attgcatata
     6661 attcacctac catccaatta ccatttggct ttttccccct caattttcca aaatagtaag
     6721 tagctccatc taatattgaa atagttgggt cttttacaat taattgagga ttaacttgat
     6781 aggtaaaacc taatccatta caatcgtgac aagctccagt atgggagtta gcattgaagg
     6841 ttgaagtatt tatcttagaa aaaatagttt gacaatgtgg acaataattt tttgtattat
     6901 tctttttttc taatggaatt ttgcaatatg gacagtaact ttttccgatt gatacaaata
     6961 acattcttaa ataatcccaa atgcttgtaa gagtaccaac agtagagcga ggattttggc
     7021 ttcctttttt ctgttcgatg gctatagtag gggttaatcc ctgaagtaaa tcaaattccg
     7081 gtttttgaag ctgttctgaa agttttgctc cgttacttag attttcaaaa taacgtcttt
     7141 ttccttcttc ataaatcgta tcgaaagcta aagaagattt tccactacca cttacacctg
     7201 taataacagt tatttgattt tttggaattg taacttcaac atcctttaaa ttgttttgcc
     7261 ttcctccttt taaatagata gagcttttat tatgacaaag tgaattttta attgatttat
     7321 ttattgcttt tgtaaatttg aatttctttt ctagttcaag aggattgcct aattctttta
     7381 tttccgaaat acctaatatt tttaactgag aaaagattga tttcaaataa tcttcaggca
     7441 atttttctat taacaaatta agggcttcta tttttatatt tccgcttgat aatatctctg
     7501 ccatttcatc taataaattt ttttctgctc ttgttaattg attgtatttt ttggaactta
     7561 attctgtcca taaatcccat ggaagcaatt ctaaaccaat catattatta aagtcatgta
     7621 gaagattacc ctttacagaa tgccaacctt tccaattttt attatatcca aagtcatctg
     7681 gatgagcatg tccttgccga catcttatcc aggcttctga accagttaaa aaaccatctg
     7741 tttttccgac atcatgagtg tcaaaattaa tttgaaaata atttttttgt atgtcatcta
     7801 tttgtgcatc tattcttatc catctctttg ttagagtatc atagtattct acaagccagt
     7861 ggtcttcata agtaagctca ctttcaaaat aattagcaaa acctgctctc attctagcct
     7921 caaaacctcg atatcttagg agcgatacaa gaagtaaaga ataatctctg cacattccaa
     7981 caagcctttg ttttgggttt cttggaatag ttagtgggtt agaatttatt tcaaatattc
     8041 tttttaacat ttgaggaatt gtacgaagca attcctcatc agattgttgc ttattaaagg
     8101 atataccata taattttcct tggtctccat gaattactag gctttgaacc acttttaata
     8161 actcaattgg agtctttggt aaatcttgat atttattttc aaatttttta ggatttgtga
     8221 tgatactttg atttttatag ttatttattt tcatttatat ttcacctctc taaatggatg
     8281 atataccctg acatggtgtc atatgcaagg acaatttaga tttttggcca aaatttaaaa
     8341 aataaataaa aaatgataca gtgataaatt gtaatacaaa tatagtttca aattgcatat
     8401 aatataatta tttaataaaa ccattatcta ttgaatgtta atgaaatgtt aagatggcat
     8461 tcttgaatat taagaaatag aatactataa tatagtgtga aggattttta gtaaaaaaat
     8521 ttgtaagtgt taatatacat taaaaaatag gtttataatt tggaggaaaa aaatgaaatt
     8581 atcaaggtat aagaaaaata gtttagttct gtctataatt ttatgttcac ttattatttc
     8641 aatccttgta attactgttt ttaataccgt aaaactacac aatatatcta ataaacaatc
     8701 taaaaactat ttaaatgatg tatctacaca gattgtaatg aatgttgatt ctaaaatcaa
     8761 atttatttta tccgacttaa gaataatggc agattttatt aagcaatatg aaggtgatag
     8821 tcgatatgag tatttatcta aaagaaagac tagttataag tattatgatg ttggaataat
     8881 agatttagaa ggtaaagctg agtttttaag tggaaaaaag tttgacttaa agaatactgt
     8941 ttcctataaa aaaggaattg aaggtaaaga atactcagaa gtaatagagt caatgggttt
     9001 tgttctttat agtgtaccta tatttaatga taatcatgaa gtatctagta ttttaatagg
     9061 tgtatccaat aaagaaagta tgaatgagat tcttaatata gataacttta atggaaaagg
     9121 aactattgaa attattaata gtaagggaaa acctcttttc ataggaaaaa atactgaatt
     9181 aataaaggac cttagccata aatataagag ttctggagat gaaccttggg cacaaaagat
     9241 gcttgaggat tttaaaaatg ataaatcagg gaatattaca ataacctcat caaaaggtgt
     9301 acaatgctta ttaacttatc atccaattac aagaggttta aatgattggc attttcttct
     9361 catagtacct gaagatgctg tacttggtga acttaataaa ttaaactctt ttacaataac
     9421 aatgacattt ataattacat gtattattgg aattataaca ttaattttat atattataag
     9481 aagaaaatat gtaaatcaaa tagaaaatat tgcatattta gatagtataa caaatggtat
     9541 aaattcaact aagtttagta tgctagtcaa acctttaatt tcagaatcac ctgatagtac
     9601 ttatatgatg atagcaatga atataaaaga ttttaagcta ataaatgatt gtttcggtag
     9661 tgaaaaggga aatatgacac taaaacatct ttacaatatt ttgtataaaa acattgatga
     9721 aaatgaagaa tttgtgtgcc gtcatgatgc agaccttttc tatttgctta ttaagaatag
     9781 accagtgtta gaagccctgg agttattata taaaatagaa gctgacacaa attattttaa
     9841 taaaaatagg gaaaatccat actttttaag actatcagta ggtatttaca caattgaaaa
     9901 tcataatgaa gatttaatta caatacaaga ccatgcaaat acagcaagaa aaagctttaa
     9961 taaaactcat caaagtgatt tttcttttta tagtgatata gaaagaaaac gattaatatc
    10021 tgaaaaggaa atttcaaatt taatggaaaa agcccttgaa aataaagaat tttttatgtg
    10081 cttacaacct aaaattgata taaaaagtgg aaaaattagt ggagcagagt ctcttgtgcg
    10141 ttggaaaaat tcagaaaagg gcataattta tccaagtgat tttattcctc ttttcgaaaa
    10201 aagtggattt atatgtaagt tagatttata tatactagaa gaaacatgca aattgatttc
    10261 taagtggata aaagaaggta aagaagtgtt gagaatttct gttaatgtat cacgtcaaca
    10321 tctgaatgat aaattgtttt tagaaaaata taagcatata tgcaataaat acaatgtacc
    10381 aacatgtctg atagatttag aacttaccga atctattttc ttagaaaatc cagaagctat
    10441 agatataata gaggatattc attctaatgg atttaaatgt tctatagacg attttggatt
    10501 tgggtactca tcattaggaa tattaaagga ttttaaagtt gacataatta agttagaccg
    10561 ttcattcttt gttagcaaaa ataatataga ccgtggtaag gtagttatta agtctattat
    10621 tgaacttagc aaaaggctag gtatgaaagt aactgctgaa ggaattgaag aattagaaca
    10681 agttgagttt ctaaaaaatg tgggatgtga ttatattcaa ggttatgttt tttcaaaacc
    10741 attattaatt tctgattttg aaaattttgc atatgaaaat aataaaatta aaaatatcca
    10801 ttattaaatg tacaagataa aaaatttagg caagttatat aattaaaaat ataacttgtc
    10861 ttttttattt atatatttaa taaaaatata tttgcagatt ttgtaaaaat aattttcaaa
    10921 tgttgtaagt tgtggctaaa gctttattgt attattctga atatagaaag atagttactg
    10981 tcttagataa aaactgaaac atacataata atataaaatt tgctatatta ataactctaa
    11041 ttattttgga aggagggaaa atatgataag tgggagaatg ttactcatca tgaattttct
    11101 aaaaggaaaa aataagacaa gttacaagga tattagcaaa caacttagta tagaagaaag
    11161 aaaagttaga tatgatataa ataatttaaa tattgttttg cgttcattaa acaagtcagt
    11221 aatacaaaag atgaacaaag gtgtgttaat tattcctgat gacttccaag tagtatgtat
    11281 aaataataac gaatatgtat tttccttaac tgagcgagta tctattatga aaattatatc
    11341 aatgtttaaa atagataatc taaacttaga aaaattaagt aaagaatttc aggtttctag
    11401 aagttcaatt aaaaatgacc ttaatgtttt gtcaagtgaa ttagaaagaa accaaataac
    11461 tattacttat gataaatctt ttaaaataag tggagaagaa gacattatat ataagcaaag
    11521 attgaacata ttaaaatcgt attcttatct ttttggtaag gaaaaatctg atttaagtgt
    11581 atttgagaag tatttagtga atgtaattga aaaaatattc aaagggattt atttgattga
    11641 tatatataat tggtctatga atttattatt gcaaatggga tggactttaa atgatgaatc
    11701 ttttacatgg tatgtgtcaa acattttcct ttttacatgg tatatacatt cagatgaaaa
    11761 acatccttta gaatctgctt cattaagtga gccgtgtttt gaaaataagt ttgaccaaga
    11821 atttgaaaca attattcaaa aaaagttgac taaggaacaa atttttctgt taaagagttt
    11881 tgtatttttt acaaataaat atgcaagttt aaacgaggat atggatttga ttagtacaga
    11941 aattatagtt caagatctaa tttacaatat gtcagaaata ttagagatta gctttaaaga
    12001 agatatgatt ctttataaag gattactcaa tcatattgcc ccattgatag agagaatcaa
    12061 acagaatata cagatttatg aggaattact tcatgtaata ccagataaat atcaatatgt
    12121 acttgaagct actaaggttt ctattcaaaa aaacagagtt ttaagtcaaa taaagaatga
    12181 aaatgaaaca atacttttgg caatacattt cttaggaagt atacatagaa atgagaggaa
    12241 taactacaaa aatatattgt tagtttgtgg atttggatat ggtgtaattg ctatgttaaa
    12301 ggatagttta gtaaatgatt accagataaa tatagtagag agtattccat catataagtt
    12361 acaagattat aaagaatggg aaagtattga cttcattata acaacatcaa agatagtaat
    12421 agacttgcct aaaacaatta ttgagataaa tccattttta caagaagagg attatttgaa
    12481 gtttgaagaa aaagggataa aaagaaagaa cgtcttaact aattatatgt caataaaaaa
    12541 aaggttggac tttttagaag aagatgccca aaaaagagta ttaagtatta tatgtcaaga
    12601 acttggatac agtgatgaga gaatattatt tagacaactt aatttaagtg atttaatagg
    12661 aattgatacc ataaggataa ttgatggaga tatgaaatgg gaagatgctg taaaaattag
    12721 ttcaaacata cttgctaatt gtgattttgt atcagcacaa tatgctgaga atattataga
    12781 tattttaaaa aatgtgggtt tttatgctgt aaaagataac gaatttgctt tactacatgg
    12841 caatgatagt tcattagtca aagtaagttc gataagttta ttaatatgta aagaagcagt
    12901 tagttttgga gataaaaagg ttaaaatcat attttgccta gcaagcagag ataaaaaaga
    12961 gcaaattcct gcaataatta atctaactaa aatggtttat aagactaatt ttattgctat
    13021 gttagaaagt gcaaagacaa aagaagaagc agaagtttta attcataaat atgagaagga
    13081 ggtcactgta tgaataaatt agttaatgta aaatgttcat ttaaaataca tgttaattca
    13141 aaagaagaag ccattatatc gttagttgat gtagtgtcaa aagaaggata tttaatagat
    13201 aaaaatcaat ttttaaaaga tgttttaaag agagaagaaa cattgtcgac ttatattgga
    13261 catggtatag gtcttcctca tagtcaaagt gtaggtgtta aaaactcttg tattacaata
    13321 ggaaagcttg atactcctat tgaatggaca gaagaaggag aaaaagtgga tttaatattt
    13381 ttgatatcag taacaaaaga caatgaaaat aatcttcatt taaagatttt atcaaaatta
    13441 gcacgtttat tgatgcatga aagttttaga aatcaaatta gatgttcaga tgaacaaact
    13501 gtttataatc ttataaaaga aaaaatagag gaggaagatt aaaatgagaa ttttaaagtt
    13561 tttgcaaaaa catcttatga cagcaacatc ttatatgatt ccatttgtgg ttgcaggagg
    13621 aatattattt gctttatcag taactttaag tggacaagct gctgttcctg aaacaggctg
    13681 gttggctaaa ctgaatcaaa ttggagctgc tggcttggct ttattcattc ctatattagg
    13741 tggatatata gcatttagta tggcagataa accaggatta gctccaggta tgataggtgc
    13801 atatttagca aaagaagtaa atgcaggttt tataggtggt atcatagcag gatttatagc
    13861 aggatttgtt gttttacaat taaagaaaat taaattagct cctacaatga gaactttagg
    13921 ttctatattt atttatcctt tagttggtac attgattaca ggtggtataa ttgtattttt
    13981 aattggagaa cctatagctt cttttatgac atggatgaca aactggttaa atggaatgtc
    14041 tggtgtttct aaaattcctt taggtggaat cttaggagga atgatagcct cagatatggg
    14101 tggccctata aataaggttg ctgctacttt tgcccaaact caagttgaca cacttccata
    14161 tttaatgggt ggagttggcg ttgcaatttg tatacctcca attggtttag gattagctac
    14221 attattgttt ccaaaaaaat ttagcaagga agaaagagat tcaggtaaag cttcactatt
    14281 aatgggatgt gttggaatta cagaaggagc tattccattt gcaacatcag atccagttag
    14341 agtaatacct tgtattatgg ctgggtcgat tgtaggaaat attatggctt ttttattagg
    14401 atgtttaaat catgcaccct ggggaggtct gatagtgtta cctgtagttg acaataggtt
    14461 ggggtatatt gcatcagtat taactggagc agtagttgtt gcggtattaa tgaaattagt
    14521 aaaaaaagac gtgaaagaag atgaagaaat tgaagaagat ttagatgaat caattgaatt
    14581 aatatttgaa gaattataaa tataaatgga aggaatttgt ataaaaaagt aaatataaaa
    14641 ctataaattt aaaggagata agaatatgaa aattgtagca gtaacatctt gtcctagtgg
    14701 agtagcacat acttacatgt cggctgaatc acttgaatta tcagccaaaa aatttggtat
    14761 agaaataaag gttgagactc aaggaagctc tggaatagat aatgaattgt cacttaaaga
    14821 tattgatgaa gcaacttgtg taatattgac taatgatgtt gagattagaa atatggaacg
    14881 ttttaaagga aagaaggtag taagaatgag tgtatctgag ataattaaga aatctgatgc
    14941 attaattaag aaaataaaag atacttttca ataaaaattg atttatttta catataactc
    15001 aaagatgttt ttaaagaaat ttttattaaa agcatctttg aaaatatctt aaaaatagaa
    15061 taaaaggaga tatagtcatg aaaaagttac caataaagac tgtcgtgcaa agattactaa
    15121 acttacaaga agaggggaaa agtgcaactc ttttaggaat tggtcctatg tcaccaaact
    15181 tgttacaagc aagttttgaa ctagcaaaag atgatgattt tcctttaatg tttatcgcaa
    15241 gtagaaatca agtagatgca gatgaactag gtggcggtta tgtaaatggt tggaatcagg
    15301 aaacttttac aaaagatatt aagaaggttg ccgacaaagt tggatttgat ggtttatatt
    15361 atttatgtag agaccatggt gggccatggc aaagagataa agagagaaat gaccatttgc
    15421 ctgttgatga agcaatggag ttaggaaaaa aatcttattt agcggacatt gaagcaggtt
    15481 ttgacctatt gatgattgac cctacaaaag acccatttga aattggaaaa gtaattccac
    15541 tagatgtagt actagaaaga actgtagaat taattgagta ttgtgaaaac gagagaaaaa
    15601 gacttaatct accagacata ggttatgagg ttggtacaga ggaaaccaat ggaggtctga
    15661 cttcaactga gacgtatgaa acatttataa ctagactaaa ggttgaactc gataatagag
    15721 gtttgccaat gccaacattt atagttggtc aaactggtac tttaactaga aagacagaac
    15781 aagtaggaac ttttaatttt agaaatgctt atgatttagc tcaaatggct aagaaatatg
    15841 gagttggttt aaaagagcat aatggcgatt acttagatga tgtaacttta ttagaacata
    15901 taccatctca aattattgct acaaatgtag ctcctcaata tggtactgaa gaaactaggg
    15961 catatttaaa attagcagaa gttgagtgta aattagaaaa agagggctta gttgagaaaa
    16021 cttctaatat cagacatgtt cttcttgtta atgcaattga atgtggacgt tggagaaaat
    16081 gggtagtagg agaacaaaaa aatctaacta ctgaagagat atttaaggat gaagttttat
    16141 ctaatgaaat actagatatt gcaggacatt atacatttaa taatgatgat gttaaaaaag
    16201 aaatagaagt gctttatgat aatttaagta agaataatat tgatggtcaa agatttgttg
    16261 tagaccatat taaacgtcct ttgcgtgatt atgcagaatg ctataactta aaaggtgtta
    16321 ctacgaggat tttaaataaa taataggact tatagtggtg agtattgtta tactaggtat
    16381 ttatagttat aattatactt accactatta aatttaggag gactaatatt ttgattaatt
    16441 taatttttga tgtagatgat actttatata atcaattaac gcctttttac actgcatata
    16501 ataaagtgtt ttcttcaata aaggatattt ctattgaaga tttatatatg agtagtagaa
    16561 agtatagtga tgaggtattt catatgactg aaaatggaga aatgccaatc aaagaaatgc
    16621 atatttatag gataatgaaa gcttttgagg agttgggaaa ttctattaca gaaaaagatg
    16681 cacaaagttt tcaagatgag tatatatatc aacaatcaca aattacacta ataccagaag
    16741 ttgagaggat tttaaatttt tctaaagaaa gaaatattaa tctaggaatt ataactaatg
    16801 gcccatcaaa ccatcaaaga atgaagttaa agcagttaaa tattgaaaac tgggttgata
    16861 aaagtaatat ttttatttct agtgaggttg gattttctaa gccagatact aatattttta
    16921 gagtagctga gaatgttatg aatttagata gagaaaatac atattatgtg ggtgattctt
    16981 atagaaatga tgtattaggt gctaaaaaag ctggttggaa gagtatatgg ttgaaccata
    17041 ggggacatga gttagaagag ttgttttata aacctgattt tgtaattttg gaacataagg
    17101 atttgatatc tttatttata aaaatatgta gttataaaaa tatgtagtaa aaaaatgtta
    17161 ataatagaat tgtataaaat aattaataat aactatataa aattatatgt ttagattgtg
    17221 agcaatctat tttatgttaa aaatagatta tttagaagaa ggggaaatct taaaaaaatt
    17281 tgaatatccc ctttttatta tttaattaaa atgaaatagt tagaaatata ttttatttag
    17341 tttagtcaat aacattttgg gattctttat aactacatgt taactgttga ataggtttat
    17401 catatggttt aacccatcct ttattaatac ttaattctgt aagtgctgtg tgaccttcta
    17461 ccatttgagt taatgaagct gaatatatag ctcttagttc aggtgtacta cttgtcaatg
    17521 cagaattaag atacatattg gcagatgctt tagcagatga aagcatactt aacattatta
    17581 ctttatcgtc tatataagta ttgttcttaa ttagattttc tatcatattt ctcatgttat
    17641 ctatacctcc tcagaaatta gtatttcatt ttcaactata aattgttgta tagctttaat
    17701 tcttccttct gttgctaata tactagattc tgattgtctt tttagatctt catctgatat
    17761 taacatattt attgctcttt gcataagtaa tccgtcagac tccattttta taattgctgc
    17821 taaagatatt ttttcagttt ctgaaagtat tctcatttaa tcatctccta tattgtaatt
    17881 tatgctttaa tagtatgtct ttcttttcaa ggaaataacc attacacttt tttacagtat
    17941 tttatattct cgttatatca aaatttagtc gacttaatat attaatataa ttttgtagga
    18001 tatttatcat taaatatcta taaaataaat tgtttgaata ttcataaagc aaaatttatt
    18061 tgtatgtact tcttcaagag taaatatgag ttttttcaaa aaattaattt ttatgataat
    18121 tattaagggc tatatttttc ttaaagttgt gattatcatt attaatttac aataaaattg
    18181 ccgaaaagcc ctctccttta ggtgtaggga tgaaaggtaa ggtcttaata taaaaaagtt
//
LOCUS       DAYAKB010000074        17981 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.074, whole genome shotgun sequence.
ACCESSION   DAYAKB010000074 DAYAKB010000000
VERSION     DAYAKB010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.074"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(134..1810)
                     /gene="bclA2"
                     /locus_tag="ACGI3L_002925"
     CDS             complement(134..1810)
                     /gene="bclA2"
                     /locus_tag="ACGI3L_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HFG9198622.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(2188..2727)
                     /gene="hpt"
                     /locus_tag="ACGI3L_002926"
     CDS             complement(2188..2727)
                     /gene="hpt"
                     /locus_tag="ACGI3L_002926"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFG9198623.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(3055..4362)
                     /locus_tag="ACGI3L_002927"
     CDS             complement(3055..4362)
                     /locus_tag="ACGI3L_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HFG9198624.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4787..6562)
                     /locus_tag="ACGI3L_002928"
     CDS             complement(4787..6562)
                     /locus_tag="ACGI3L_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198625.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6559..6696)
                     /locus_tag="ACGI3L_002929"
     CDS             complement(6559..6696)
                     /locus_tag="ACGI3L_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198626.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(6774..7343)
                     /locus_tag="ACGI3L_002930"
     CDS             complement(6774..7343)
                     /locus_tag="ACGI3L_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFG9198627.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7527..8162)
                     /locus_tag="ACGI3L_002931"
     CDS             complement(7527..8162)
                     /locus_tag="ACGI3L_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9198628.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(8830..9711)
                     /locus_tag="ACGI3L_002932"
     CDS             complement(8830..9711)
                     /locus_tag="ACGI3L_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFG9198629.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(9831..10838)
                     /locus_tag="ACGI3L_002933"
     CDS             complement(9831..10838)
                     /locus_tag="ACGI3L_002933"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HFG9198630.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(10858..11331)
                     /locus_tag="ACGI3L_002934"
     CDS             complement(10858..11331)
                     /locus_tag="ACGI3L_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HFG9198631.1"
                     /translation="MGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNE
                     WKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGAD
                     GLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK"
     gene            complement(11358..11825)
                     /locus_tag="ACGI3L_002935"
     CDS             complement(11358..11825)
                     /locus_tag="ACGI3L_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HFG9198632.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(11840..12598)
                     /gene="prdD"
                     /locus_tag="ACGI3L_002936"
     CDS             complement(11840..12598)
                     /gene="prdD"
                     /locus_tag="ACGI3L_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HFG9198633.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(12678..13403)
                     /gene="prdB"
                     /locus_tag="ACGI3L_002937"
     CDS             complement(12678..13403)
                     /gene="prdB"
                     /locus_tag="ACGI3L_002937"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(12951..12953),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HFG9198634.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(13441..13725)
                     /locus_tag="ACGI3L_002938"
     CDS             complement(13441..13725)
                     /locus_tag="ACGI3L_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBO2463/CBO2479 domain-containing protein"
                     /protein_id="HFG9198635.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(13806..15686)
                     /gene="prdA"
                     /locus_tag="ACGI3L_002939"
     CDS             complement(13806..15686)
                     /gene="prdA"
                     /locus_tag="ACGI3L_002939"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HFG9198636.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(16115..17875)
                     /gene="prdR"
                     /locus_tag="ACGI3L_002940"
     CDS             complement(16115..17875)
                     /gene="prdR"
                     /locus_tag="ACGI3L_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HFG9198637.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
BASE COUNT         5158 a         3559 c         2126 g         7138 t
ORIGIN      
        1 tttattggta tatgaaatca tattgtttat tattttatag tcttttcatc atataaacct
       61 attaaatatt attctattta ttggtatatg aaatcatatt gtttattatt ttataatctt
      121 ttcatcatat aaactattgt attctataaa ctgatacata tccagctgca gaagtacctg
      181 tcgtgcctga accaaatgta aaacttaaag taacagctgc tgctctagca tcaactaaaa
      241 agcttaaact tacacttaca tctgatgaag taagtgtatt tactgctttt gcaataaagt
      301 tattttgagc tactccatta aagttagtag taattgacat aaatcctgca agtgaaagtg
      361 tggcacgtat accgaaagat acattgtata tccctccaac tgcaagattt atagtactac
      421 ttgttggaaa agttatatta gttccattta taaatgatga attaaatgtc actaatgtat
      481 tattcactaa acttgaagag gacactgtaa attgtgcatt gtttgctgct aacactcctg
      541 ttgctccggt cgctccggtt ggacctgttg ctccatttgc tcctgttgct ccggtcgccc
      601 ctgttgctcc tgtcgctcca tttgctccag ttgggcctgt tggtcctatc gctcctgcta
      661 ctccatttgc tcccgttgct cctactgctc cggttgggcc tgttgctcca tttgcccctg
      721 ttgctcctgt cgctcctgtt gctcctgcta ctccatttgc tccggttgga cctgttggac
      781 ctattggacc tgctactcca ttcgctccgg ttgctcctac tgctcccgtt gggcctgttg
      841 ctccatttgc ccctgttgct cctgtcgctc cggttggacc tactgctcca tctgctcccg
      901 ttgggcctgt tgctcctact gctcctgttg gacctattgc cccagctact cctgttgctc
      961 ctgtcgctcc tgttggacct accaaaccat ttgctccagt tgctccggtt gggcctgttg
     1021 ggcctaccaa accatttgct ccagttgctc cggttgggcc tgttgggcct gttggaccta
     1081 ccaaaccatc tggacctgtt gctcctactg ctcctgttgg acctacctct ccatctgctc
     1141 ctgttgctcc ggttgctcct attgggcctg ttgccccagt tgttcctgtt gctcctgtcg
     1201 ctcctatact tccggttgga cctgttgctc ctgtatttcc tgttgggcct gtagcacctg
     1261 ttactccatt tgctccggtt gctcctgtat ttcctgttgg acctgttatt ccatttgctc
     1321 cggttgctcc ggttgctcca gttagtccgg ttggacctgt tgctccagtt gctcctgtat
     1381 tccctgttgg acctgttatt ccatttgctc cagtcgctcc tgtatttcct gttggtcctg
     1441 tagagcctgt tattccattt gctccagttg ctcctttgtt tcctgttgga cctgttattc
     1501 catttgctcc ggttgctcct gtattccctg tcggacctgt tattccattc gctccagtcg
     1561 ctcctgtatt tcctgttggt cctgtagagc ctgttgttcc atttgctcca gtcgctccca
     1621 tatttcctgt tggtcccgtt attccattcg ccccggttgc tcccgtattt cctgttggac
     1681 ctgttattcc atttgctccg gtcgctccag ttgcacctct aggccccgtc ggtcctgttg
     1741 gaccagtagc acctgttggc cctgttggac ctacatcttg atataaactt ggacctgaaa
     1801 tatcactcat ataattaatc ctcctttttt aaagttagag tattactcta taaatattga
     1861 gtattactct atataattat atgaatcgac aatttcttat gtgataatgt atctatttgc
     1921 ttatatcaac atatatgctt tgattcttga atttcattac ttttttgtaa aatcttttac
     1981 aattattagt actcttttac aattattaat acaattaaaa aactcatttt ccatcaatta
     2041 tttaaaattt ttttattatg ttataaaaaa tagataatta aattgcataa aattaattta
     2101 atactacttt aattactttg taaataaaaa aacctcaaca cgattaataa aaatcatatt
     2161 aaggcatcca caaaattata taattgctta tctatcttca tcagtaacat tgaatatata
     2221 aggaacattt ctataataat caccaaaatc aaacccatat ccaaccacaa acttatcttc
     2281 tatttcaaat ccacaataat ctggcactaa atcgactttt cttctgcttg gtttatccaa
     2341 aagaacacaa cattttaaac tagcaggatt tttagctttt aaatgtttta acacaaaatc
     2401 catagtaagt gcagaatcag taatatcgtc tacaaccaaa acatcatatc ctgctatatc
     2461 agtagtcaca tctgaaacta ctttaaccct tccagtactt tcttcattgt ttccataact
     2521 agatgtagtc ataaaattaa ctctaagtgg taaatttata tttctaacta agtctgcaca
     2581 aaatataaag ctacctttta atagagaaac taccataaga tttttatctt tataatcttt
     2641 ttctataatt gctcctaatt cccttaattt atctttaatt ttttcttctg aatacaatac
     2701 ttcccatttt tttgtttcta tatccataaa aagacctcca attgtaataa tccttcttaa
     2761 ttttataaga gattgctcac tttttcaata ctcttattca atattagtca atattattga
     2821 gtttttatgt tcattcaaca attattaaca atgtatctta tattttaagt agttcatata
     2881 tccacactaa attacatact atatatttta gacaaaaaaa gaaaaaactt gcactaacaa
     2941 gttttttcta ttatacataa atttatacat aatcatattt tattagaggg tactaattaa
     3001 atttatttat gctatttttg ttatacctca taatacaaaa catattataa agtactagtc
     3061 aactttattc atatcattca ttacatttaa gattatctca tctgttatag acataccttt
     3121 gtcacttact ctacctaagt tttgtatact ttgctcaaca cttgaaccaa ctataccatt
     3181 tagtggtggt acaaaacaat cttgcttagc tattatagca ctttgtatag ctgcagatgc
     3241 tgcagaagat aattttaatg cacaaccagc tttcgcaccg tcacatatca ttccacttaa
     3301 gtcagctatc atattttcta tagctccttc tatttgcttt tcagtaccat tcataagcca
     3361 agagatacca gcagttgctc cagtagaagc agcaacacca catccacata cagcagataa
     3421 tcttcctgta tagttcttaa tataaccagt tactagatga gatatagcta aagcttttgc
     3481 tagtctttca tcagattgtg ggaatttttt attataagca acgattggaa gaattgctgt
     3541 taatccatga tttccacttc catttgaact cataacaggc atttttaccc ctgccattct
     3601 tgcatctgaa gctccagcag ttaacatcat tgcataattt ataacatcat tacctaaaag
     3661 accttcttct atagactttt taattccata cccgacacca ataccagttt tttgttttaa
     3721 tccatattca gccatctctt cattcatttt tactccatct agtaaaaatt ctatatcttt
     3781 aaaatcaatt tcttctacat tttttattaa ttcttgtata gttactgtat ccattaaact
     3841 ttcagctttt tctgccgcat catttgaagc tgatactttt ggttcattgt ctaataatac
     3901 ttctccatct ttttctaaga acgtaaaatt atcatgttta gttcttattc tcactttagc
     3961 aatatgattt tttcctttta acacaacttc tataaatact ttctctcttg tatcagcagg
     4021 tgttattgat agtggagtat tatccatata atcctcagct attttaactt cctcttttgt
     4081 tagagtttct aacacactta atccattttc agaatgtcca cctactatac ctagagctgc
     4141 tgcaattttt aatcctaatc tttcagtacc tggtatacct acacacatac catttttata
     4201 gatactagga ctaactaaca tacgattttc aactatttct tctcctaata attcctttgc
     4261 ctttgcacat gctagagcta aggctactgg ttcagtacac cctactgctg gtttaacttc
     4321 tgcctttaac atttccacta attcttttct tatatctctc attatatata aacctcccaa
     4381 ttaagtttag atttagtact caaataatta gttaaataat ttcttatcta tatttatagc
     4441 aaaatacatg ccatattttt tatatctttt tatattttta gtcttatatt ctataaccat
     4501 tggtatgact gcctctattt atgtattttt tttatttgta tagagtattt atattcttta
     4561 aaatggagaa acatatgaca atttcgcaaa aagacaaaaa aaagtctcaa aatgagattc
     4621 tatatcattt tgagacggct caaatatatt attttttaac ttataaaaac cattttttaa
     4681 ttcataaaaa aagattctgc aaaacactta tagtataagt ttaaagcttt ctttaaagtt
     4741 atgaatttag aaaaatttaa attttatata gctttttatt atattactat gaaattatat
     4801 tgtatttttc aatttttcta tataatgtag ctcttgatat tccaagtgct ttagctgtta
     4861 attctttatc ttttttataa tctttatact tatttaaagc ttttattatc tcaatcttct
     4921 ctagttcatc aagtggaatt atcctatcgc ttttaacttc taactcttct acagaggtat
     4981 tcttaatttt ttgaggaatt acattcattg tgattattga agaagaagac atattcacac
     5041 tatattcaat aatattctgc aactctctta tattccctgg ccacttatat tccatcatag
     5101 catcaacaac cctgctatct atgtcaataa catttttatc taattttttt gaatactctt
     5161 taaccatatg cttgattata agtgggatat cttcttttct ctctcttaaa cttggtaatt
     5221 ttataggtat aacatttaat ctataatata aatcttctct aaaagtgcca ttttgaacca
     5281 ttctttctaa atctttattt gtagcagcaa taattcttac atctattgaa acatttgatt
     5341 tacttccaat tttattaagt tccttttctt gtaatactct caataacttt gactgtaaat
     5401 gcaaactcat atctcctatt tcatctaaaa atatacttcc cttatgagct acttcaaaca
     5461 ttccaagctt tccacctttt ttagctccag taaaagctcc ctcttcatat ccaaataatt
     5521 cactctctaa taaattatcc ggtatagcag cacagtttac agctataaaa ggattatcta
     5581 ctctattgct atggttgtgt atggctcttg caaatagctc cttacccgtt ccactttccc
     5641 cagtaataag tactgttgat gttgatttag aagctattag ggcttccttt ttagaatttc
     5701 ttatagctac actttctcca attatgtttt ccaattttat tctataatct ttattcatct
     5761 tattgtagtt ttttatagca tctcttttat ctataaaatc aataacatat ccctttaact
     5821 cattttttaa tactatttta ttgatgttgt atattccctt cgaatcatat ccgtatcttt
     5881 tataaaaaaa actacaggat ttgtccttct taaagttatt tatagaaggt ttctttataa
     5941 aatctaactc gacaaatatg tttttgccag ttatactatc ttttatattg aaaagctctt
     6001 taaattttga attatattta tcaatttttc catccacatc aatagacaca acagctttgt
     6061 ccatattgtt taatagtgtc tctaattttt tcttttctaa ttcaagctca taagttttaa
     6121 tttgtgcttt taatttatta gatattaggt ctgccatttt gcctaaaaag tttataagac
     6181 cacttttatt attttctata atttgtgctt gttcttttgt aaaggctata aggcctataa
     6241 caccatgaga atcgccatca catataatag gacaacacac ctctgcaaac tctacacaag
     6301 ccccactttt atagcattcc ctacatatat cactactctt tgggtcatca attagtattg
     6361 taatctgttc tgtaagtgat tttttaaaag ccgtatattt atctactttc tcacctattt
     6421 tgtctatata tactcctgta cctgcaatcc taaataactc cttatttact atagttacat
     6481 ctatattgag tactgatact atagcttcag ctatattttg aatatcagat tttatatatt
     6541 ctaaacctat cataatcatc attccttatt tttctttagc ataagtattt gtcttatttc
     6601 tttaagaatc aagtatatct tatttaaagt aaattggatt gacatcagga ttacaaagag
     6661 cataacaatt attattaact cataatttat ttccatctaa acatctcctt ataacaaaag
     6721 actaggctta acctagtctt ttatattata tccatattta tattttaact catttatctt
     6781 ctttttccca cataaatata ttttaattta tttgactctt taatcatacc atcaaagttt
     6841 aatcttgaaa atatattaaa tacttcatgt ggatagtgaa tctttgcaac agaaccacaa
     6901 aatttatgtt taagatagtt taacttaact tttaaatttt ttaaatttaa atcctctaat
     6961 ataacctctc cattgccctt taacactctt tgtatttcag atgaagcttt ttcacaatct
     7021 gtaataacat taaattggtc aactattatt atcttgttga actgattatc atcaaatggt
     7081 agaaactcta acttaccttt aactacattg caattttcat tatacactag agaataacag
     7141 acatcttcat aattactatt ctccagtata gttacagaag ttccaagacc tctcaatctc
     7201 ttgcctaggt ttcctatatg accaacaagc aatattttat cacctacatt atactcaatt
     7261 gtatccaaaa aacattctaa ttcatcagat gtatatttag ctttaactgg ctgtttattt
     7321 atctgacata atatgctttt cacaatgctt cacctcttca tttcctcaat tataaattat
     7381 gtacagatta cattataata aatggcgagc aactattcaa gagatatttc attagtattt
     7441 ttttaaacaa tctttataca ttttaatatg atattatacc aaatttatta ggattttatt
     7501 cataaaaatc agtctatttt ttatgtttat tcattgttat tttcatccaa tttttttatt
     7561 ttcgatatgg atacttcata tgccattttt ttgaccacat tattttcatc tatttttttc
     7621 tcatattctc tactttgaac cctaccccaa agctgtattc tatcaccaac ctttagattc
     7681 tttgcaaatt tagcatttct accccaaact attgatggta tataatcaga tttattataa
     7741 ggtctgttta tagcaactaa taaatcggtt atttcccttc ctaaaggtgt cttcctatac
     7801 acaggttcct tacatacata tccatctaaa aatatactat tagggtcttt attttcctcg
     7861 tctatacttt ttatttctct gacaaacact gtaagcacta atctattttt attatttaat
     7921 gttttgttat atgatcttaa ttggcctacg acattgacta aattttgttt atcaaggtca
     7981 atatcttgga gaagtctttc tgatacagtc attggaagta tatcaaaaga atcgcttagt
     8041 ctgtttattt ttattttcat attataaaat ttttctccaa atatctcatg gctaaattct
     8101 agcttattgt ctaactcccc tcttaagttt actacgttat tctcatcttt aacagctatc
     8161 atattttatc cctccacaat tgttaattct tatatttctg gtatcagctt atataataaa
     8221 tatatttata agggatgtat tttattacaa atctttgatt gctgtttaaa agtttttatt
     8281 tagttataaa tttcatttaa tatttcactt ttataattat aaaattatta tctttttgta
     8341 ccacatatac taattaaact acctatttca gttttgtatt aattataaaa atcctattat
     8401 ataattaata agtcatatat aacttaaatt tattcactct atataagcaa cttcaacgaa
     8461 ttaaatttat tgaaataatt cagatgaata ttgagtcatt ataaacttat ttttcttaat
     8521 tataagttat attagactta ttacaggtta tatttttatt aatctgtatt aatatatgaa
     8581 catttattga acttattgat tataaaattt aaatatttag ctttaaatta tgctttattc
     8641 tttaaaaata caacgttttt tagattaaat ctactaaatc actatatata ttacataatt
     8701 ggcatgttaa ttgctttata ttaatttagt aaataaaaaa ctgccctaaa atattaattc
     8761 aatattttaa agcagtttat aatctttatt attagctgta atatttaata aacactaagt
     8821 agtctttaac taagcagtct ttttgttttt atttgcagcc attatcattg tagcagaagt
     8881 ataagctata actactatta ctaatgcttt taatatatcc attggtagag tttttactat
     8941 atatgcagct acgaaaactc ctattaaacc acatatagct attataactg atgctttttt
     9001 agtatatgca tcttctttta tgaatttcat acttgcaact ggcattaata atgcacaaga
     9061 acccataact attgggaatg caacttttgc agacattcct aagaaataaa ccattgccat
     9121 acctggagca tatagaccta taccagctgt cattaaagct cctagtataa agttacctat
     9181 tacacctatt actaatttag caccagtaag acctaattca tttcctccac ctggtaatac
     9241 gttaatccaa ggatgaccta ataacattaa tattgctgtt aatgctaaag ttacacccat
     9301 aacaagttgt atttttctct cgtccatctt agctattatt cctgcaccta tatatgaacc
     9361 aactgctgct gccacaacca tagatactaa agtaacacca tctactggga taattgatgt
     9421 aaatatgaat gcttctgtaa caactggaat agtatgtgct acgtttaatg taccaggcat
     9481 ttttttatct ggtatattta actttaaagc ctttgacatt gctattgttg gagcaaatga
     9541 ccctattcct aatgtatcaa agaagtctgt tataaatcct gttacagcaa cttttggagt
     9601 actttgttct tctagtttcc cctctttgtt tgctttagct acgtctttac caaacacaac
     9661 tgcaaagatt gctgcgaata ctacatataa tgcctttaag attgctacca taatccatcc
     9721 tcctattttt ttattttttc atatattctg aatcttatag cctaaaagct atagaatagc
     9781 aaccgacaag tggctactat tctattttaa tttcctaatt tatttattac ttatttaaga
     9841 ataaatccat gtttaagtgg gtcttcttca tctattacaa aatgattaaa tccagttata
     9901 taagcagaac cagttatttt aggtactaca gcattgaaat ctgcaacttt agtttcttca
     9961 actatttcac ctttgaataa agttcctaat atactttcat atacgaattt ttctcctact
    10021 tttaattcac ctttagcatg taaagtagct aatttagcac ttgttccagt tccacatgga
    10081 gatctgtcaa cttgaccttg accaaatata actacatttt tgtaagtagc ttctggatga
    10141 gttggctcat catatatttc aactaagtct acagttttta tatgagctaa agttggatgt
    10201 tgtatttcta ttttctcatt tattatatct ctaagtttca tagctagttc agttaattta
    10261 ccagcatttt gaggttcgat ttttaaacct aattgacttg catgtattat agcaaagaag
    10321 cttccaccaa atgatatgtc aaatttaaca gttccaacac ctggtaagtc aacttcaaca
    10381 ccttctttat ataagaaagc tggtacgttt aagaatgata cttctttagc ttttccatct
    10441 acaactgtaa cgtctcctct tattattcct gctggagctt ccataactac atgagttaca
    10501 ggctctactg ctggaactac acctgtttct atagctgctg tcatagctcc tattgtacca
    10561 tggccacaca tgttaaggta tccgccacca tccatgaaga ttattccaaa gtcagcatct
    10621 gggcaacaag gttgagtcat tacagaacca aacatatcat tatgtcctct tggctctaac
    10681 attatagcag ttcttaaata atctagattt tcctctaaat attctttttt ctcaggcata
    10741 gaatttcctt ttatgttagg tattccacct acaactattc tagtcgcttc acctgctgta
    10801 tgagagtcta tagcttgtat acttctgcta aatttcatat caaattcccc cttaggttta
    10861 ttttgcgtct ttacgcattt ttaattttag gaaagccaat gcttttttaa catcaacttc
    10921 atccatgtga ttgtctccaa ctacttctgt ttctatgtag cctgttgtct ttttataatc
    10981 aattatggta gctttatcca aatatggatt ggtaattact aatccatctg ctcccataat
    11041 agtaagacct actgtaggta tatctgattt tacaaactct gctatagcat ttgtaaaatc
    11101 aatatgctgg tttcctgcca tatctaaagt tataatcact ccatcaggtc gcaatgattc
    11161 aatccatctt ccaagtctag ttgctaaaaa tgttttccat tcattgtgct ctgatgtccc
    11221 aactacaacc actcctaaca agtctatgtc agaatcatta tctatcaaat ctagtaacgg
    11281 gtctctaaat atatgaagtg atgtgttttt cattgatgta gaaattccca caaaactcat
    11341 tcccttactt aaatttttta tccatgtttt ctcattttaa gttttaaaaa tgccaaagct
    11401 tttttagcat ctatttcatt tgtgttgttt tctccaacta cttctgtctc aataccttct
    11461 tttgatttgt tcatatcaac tatggtatcc atatattgat tgcttacaac aaacttagct
    11521 tgagtcccat taaatgtaac tccaactaca ggtatatctc tttttcctat ttcctcaaat
    11581 gtgttagcgt agtcaacatg tgagtttccc caaccatctg atgaaactat agctccatct
    11641 actctcatgg cttccagcca agcggccgtt ctttgtccca caaaggtttt attttcattt
    11701 ccatctggag ttcctactac tattactcca agtaaatcta catccttatc actttcaact
    11761 atgtctaaaa gtgggtctct aaagtgatga agagatgttt cttttgttga aggtcctatt
    11821 cccataatat ccacctctct taagtcatag ctctaagggc accatctctg tattcattag
    11881 gagatataat cataggtaca tttcccatat ctataattga tgttcctcct tcaaatccac
    11941 taggttcctt tgagaataac tgattgtcat acatagcacc ttgacctgct atttgtttta
    12001 ctatgacaac cttttttgca tttggtcgaa ttttgtcaaa atattcacga acttgagtag
    12061 catttcttcc gtcttccatt ttcaaagacg ctcttatttc ttgtataaaa tcatcacatg
    12121 ctctgaatgc tgcaagtgga agtgttcttt caaaaggtaa acctcccttt aaagttacat
    12181 ctacatggat tatataatct tcaactgatg gagttccata tctcccaaat accatttggt
    12241 ctttcaaaat tccttctgaa gaaccaaatt catgcatttg atttccatct tcatctgcac
    12301 cagttaacat tacatataca cccgttaaag tatgtgtaat accctctccc agtctgccta
    12361 aaacttttgt tgatattggt ataatgtcca taatagtatt aatttctctg tcataatctc
    12421 caggttttat aatgtctact tttatgtctg ttattaactc ttctctttct tttatttcat
    12481 ctatacttga taaatctatt gtaagtacat ctttctttat agaagttttt gaaccgaaat
    12541 taacttcatt catatgaaac ggttttataa caagtcttct cattattttt tcttccataa
    12601 tatccacctt tgttcttaaa acccctctcc taaccgtgta ggagaagggt tctatatttt
    12661 caaatataaa ttacatttta aacgtgagct ttatattcgt atggtaatgg aactatctta
    12721 ccagcagatg gtattgcaac taattgctct aatgtatctc ttaatatatg tgtttgcatt
    12781 tctatattat gtggttcacc agcattagca cccattggaa ctaatggagc aactgctcta
    12841 ggagttccgt tttgtctaac tactggagga agagctgcta ttattattgt aggtattcca
    12901 gcttcctcta ttgctctctg cacgatcacg gcagttctat ggcaagtacc tcagccagct
    12961 gtcataacta caccgtctac tccctcttcc ttaagtttag cagcgatagc aggaccagtt
    13021 tcttcagtga agacatgttg gtttcctcca ccacccatga atgcatagtg cataggagct
    13081 actcctttga taaatccttc tgcagctaat tcatgtaatc tatctatagg gaacatacag
    13141 tttatatctt tgtttacatc tccattgtca tatccaccat gtgataccat catttcatca
    13201 actgtagctg tattaggtat agctctaaat gtagtatctc ctgctagatt aaatctcttg
    13261 tcagatttta aatgaacacc agctgctgta gctaaagcta tagtcatatc ttttaattct
    13321 ttagttacag gagtccaaac tggaggaggt gttattggaa cgaatatttc agattgaagt
    13381 ccttgtactg ttgtaaggct catatatttc ctctcccttc tattttcaaa cgattattta
    13441 ttatttttct tcttgttttg attgcatttc tgcttgtttt tctttttctc tcctaatatt
    13501 ttctacatac tcttgattag gctctggact taatacctca ggatagctta gcatgaatcc
    13561 aacttcttga cctatcttaa gttcgtagtc agttataagc attctattag gtattttaaa
    13621 ttgtccaagt ctacctttta ggtctatagt cactccaccg cctttgatgt caactataat
    13681 accttcataa aaagtctctg atgagatata ttttaaccta tccattataa ttctacctct
    13741 ctatactgtt ttaaacttgg atctaaattt atgttattgt ctaaatctta gttagtatct
    13801 aaattttagt tttcgtcttt ttcgtatatt tctcttctct tcttactcat tggtagagat
    13861 tgctcattct cttctaatac tattttttct cctgtaactt tttctatagc ttctatgtta
    13921 tttaatttaa catttggatt ccattttctt tcaggagctt taacttctac accttctata
    13981 gcatttttaa gcatagccat tattctaaca gcatcttctg gagctaaagt gttgttagat
    14041 aatatttcat tctctatacc ttgcttagac ttattgttgt ctaccatgtg agtcatgtat
    14101 ttattaccaa caactagagc accttgaaca gctgagaaac ttacaccaac tactggtata
    14161 cctctcatac ctatttgctc tatgtgagat gcgaaatcta tatggttgtt tccgaaacct
    14221 tcagtagtta ctacagctcc atcaacttcc atagcttcaa ctaacatacc taatctctta
    14281 gatacataga atttctcagc atttacttgt ggagaaccaa caaatacaac acctactaaa
    14341 tctatttctt cgtcttccat agctcttatt actaatggct ctctccagta atgtcttgac
    14401 atttcttttg atgcaggtcc tatacaagtt aatgcatgga taccaccatc taatacttca
    14461 agtggagata atacaactgg catgtttcct aagtcaacgt ttggttgagc tcctaatgta
    14521 ccaactggct caactggtaa tattaggtta tcatgcattg caccttgtcc cattatttct
    14581 tttataacaa caactttctt tttaccttct cttctgtatt gctctattac ttcttcatca
    14641 actactaaag agttgtcaac tttctttaat gcttctctta tttcttgagt tacatagtca
    14701 aatgcacggt gagcagctaa aggtcctggt ctttccatgt tagttcctgc ttttattgtt
    14761 acttgacctt tgatgaatat ttcacctttg tcagcagcac ctggtctacc ccacattata
    14821 gtagtattta actcaccttc tgaagaacca aattcaccta tttgaactcc atcttcatct
    14881 gtaccagtta ataccattac agctccatct ataactctag ttatacctga acctaattcg
    14941 ccttcttctt tagtagcgat tggttgtata tctaatacag cttcactgta agtttcatat
    15001 ttatcaggag ttattatttc taacttcata tctacaacta actcttgagt ttcattagct
    15061 tctttacata tttcttctgc gtttctgatg tataaagtag ttccttctat tttagtttca
    15121 tcagcaaatt caactttatc tattttaaag tgttttttag ttaagcttct taaaagtttc
    15181 ttttcttcaa cttttggagc tacttctgct gctgcacttg ccactggagc agcaacgttt
    15241 gctactggag cagcaactcc tgcttgacca gctactgata aaggtatctc taagcttatg
    15301 ttcttacctt cacctatgtg tattttaact gtttcacctg caactcctgt gcttactgga
    15361 actactgctg cttctgatac tggagctgct tcttctactg tttcttctac tacttcttct
    15421 ttagcctctc ctgctttgta tccttctacg ttatctgtag tcattggaga aagtgcatct
    15481 aaagtttctt ttaacttagc tcctagtact tgacctatag ttaatccatt ttctggtatt
    15541 gttaataatc cagaatcctc taagtctgca aatattgctg gatcttctaa gttttctggc
    15601 gctataattg ttcccgcttc aaatctacaa caacaaactg ctgggtcatt tgcatgggct
    15661 tgagctgttt ctaaagttat tgacatagta taaaatacct ccttacatta ttttcttatt
    15721 tattatttta aatctcaatt cctcaacagg taacccctta actgagaaat taagtaaatt
    15781 aaaacctaca taatttgtta tgattaatat tatttttttc tcacttaaag tcactttata
    15841 ttataagcaa ttcctatgcc aacttattaa caaaaagatt ttttctataa tagattcttc
    15901 atctatcgct atttttagcc aaatattata taaatattta tttaaaatat gttatttttt
    15961 gtatttgtaa acattttctc aaacaaaaaa agtgtcaatt aatcaacact ttttcatttt
    16021 ttttaacaca tctatataca caacacttat ataagcgttg gctttactag gttttaaatt
    16081 aaagtttatc attttgtcaa aatttagtca tgtgtcatat tttagacaca tctattttgt
    16141 attggtctat cttataatac aaagttgttc tgggtatatt taatatctta gctgctttag
    16201 ctttatttcc attagacatt ttaagtgcct tggttatatt ctttatttca attttttgag
    16261 ttgccttcgt taaatctaaa ggatactctt cttcttcagt actattattt gtagaatcca
    16321 tcatataact tggtacatca tccacatcta ttttagaatt ttgtgacaat acaacaatat
    16381 tttcaatcgt attttttaat tctctaatat tacctttcca tctataattc tgaaatatat
    16441 ctattacatc tttgctaatt gtaagaacag gcttattatt ttgtttacat atctcctcta
    16501 aaaagctatg aaccaataat cctatgtctt cttttctctc tctaagtgga ggaatcttta
    16561 tttcaacaac atttaatcta tagtataaat cttctctaaa tttttctgcc tttaccattt
    16621 tactcaaatc tttattggta gctgatatta ttctaggatt tatttttatt gtggtatctc
    16681 caccaactct tcttatttct ttttcctgta atactctaag caactttgct tgcatactaa
    16741 gaggtaaatc ggcaatttca tctaaaaata cagttccatc ttttgcaagt tcaaatatac
    16801 ctattcgacc ctttttactt gctcctgtaa acgcacctga ttcataccca aaaaactcac
    16861 tttcaaataa ctcatttggt atggcactac agttaacagg tataaattga ccttttctct
    16921 cactataatc atgaatagct cttgcaaata cttctttacc tgtaccactt tcgccccaaa
    16981 taaatatgct actatttgtt ctagccactt gttttgcaat cgctttcgat ttttccaatt
    17041 tataactttt acctaaaatc ttatcaaaac tacctttaga taaatttttg acttcgttct
    17101 ttagatattt taatgtatca tttacttttt caagttcaag agctaatatc ttagcttctg
    17161 taacatcaac ttctgtacat acaacaccga taaattcttc tttataaaat ataggatttg
    17221 catgaactaa tgcatacata ttttcttttt tatctgtaaa atacaagtca ctcattccaa
    17281 ctttactatt tagtactttt tctgaaatag tattttccaa aaattcattc atcggtcgac
    17341 caactatatc ttcagacttt atatcatacc tttcctccat aaacttattc cacaagataa
    17401 caacaccttc gttatttata gcacaaattc cttctttaat ttgacctata atatacttca
    17461 aagttaatcc ataatcttct aaatgcatat atagatagtc cctaatgtgc tcttgtttta
    17521 gaactccaat aattttatta tctctaagaa caggaagaat ccctatattt tttaatatca
    17581 ttatatctct acattcatct aaggttaaac cttcgttgac atatattaca tccttcttca
    17641 ttataagttt tactggttga ccttcatact ttttatgcat ctcataaaga ttatgtatat
    17701 ccgtcatgga tataatgcct tttaattggt cagatgaatc tattaccatt agagtttttg
    17761 tgttgctttt tatcatttct tttattgcat cttcaattct tgtgtcttcg tctatagttg
    17821 taaattttgt atccattacc tcttctactt tttttacttc tggtatcgaa aacataaagt
    17881 ccccccttta tagtagtacc tcatcaaaac ttatttatat atatttattc tagcatatta
    17941 taataattat ttattaaata attattatta aaatttatta a
//
LOCUS       DAYAKB010000075        17643 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.075, whole genome shotgun sequence.
ACCESSION   DAYAKB010000075 DAYAKB010000000
VERSION     DAYAKB010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.075"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            87..875
                     /locus_tag="ACGI3L_002941"
     CDS             87..875
                     /locus_tag="ACGI3L_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HFG9198638.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            896..1636
                     /locus_tag="ACGI3L_002942"
     CDS             896..1636
                     /locus_tag="ACGI3L_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HFG9198639.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            1812..2186
                     /locus_tag="ACGI3L_002943"
     CDS             1812..2186
                     /locus_tag="ACGI3L_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198640.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            2278..3738
                     /locus_tag="ACGI3L_002944"
     CDS             2278..3738
                     /locus_tag="ACGI3L_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFG9198641.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            3791..6820
                     /locus_tag="ACGI3L_002945"
     CDS             3791..6820
                     /locus_tag="ACGI3L_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9198642.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            6897..8963
                     /locus_tag="ACGI3L_002946"
     CDS             6897..8963
                     /locus_tag="ACGI3L_002946"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFG9198643.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    9681..9891
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10117..10932
                     /locus_tag="ACGI3L_002947"
     CDS             10117..10932
                     /locus_tag="ACGI3L_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9198644.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            10960..11637
                     /locus_tag="ACGI3L_002948"
     CDS             10960..11637
                     /locus_tag="ACGI3L_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFG9198645.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            11696..12418
                     /locus_tag="ACGI3L_002949"
     CDS             11696..12418
                     /locus_tag="ACGI3L_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFG9198646.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            13065..14216
                     /locus_tag="ACGI3L_002950"
     CDS             13065..14216
                     /locus_tag="ACGI3L_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFG9198647.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            14262..15437
                     /gene="thiI"
                     /locus_tag="ACGI3L_002951"
     CDS             14262..15437
                     /gene="thiI"
                     /locus_tag="ACGI3L_002951"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFG9198648.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEESTILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            15593..16396
                     /locus_tag="ACGI3L_002952"
     CDS             15593..16396
                     /locus_tag="ACGI3L_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFG9198649.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            16639..17280
                     /locus_tag="ACGI3L_002953"
     CDS             16639..17280
                     /locus_tag="ACGI3L_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HFG9198650.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         7147 a         1681 c         3236 g         5579 t
ORIGIN      
        1 ttattaaagg ctatttttat taaagatagt ctttttataa tgtcataaat gattagatat
       61 gtataactaa agaaaggagg gaatagatga caactttaat ttttttcata gtggggatag
      121 catctttggt agttgctttt gttattgatg ggggacatgt tggagcatta tttgtatttt
      181 catcagcact tgttgtgttt ggtggaacta taggagctgt tggagcttcg actccattcc
      241 ctgtgtttaa aaagtctata aagataatgt tattagcttt taaaaataaa aagcctaata
      301 acatagaaaa tataatctat ttcaaagaaa ttgcaacaaa ggctaggaaa gaggggcttc
      361 ttagtattga caaagaaata agtgagaatg atgaattaga cccttttatt agaaaagggc
      421 ttgaacttat ggtagatgga gtggatgcag ttactataag aaatatattg gaatcacaga
      481 tacagataac atcaaaacga cataaagaag gaatagcaat ttttgattca gcaggtggat
      541 atgcacctac actggggata ataggtacag ttatgggatt agtacatatt ttaggtaatc
      601 tttcaagtaa tccagatgca ttaggacctc aaatttctgt tgcattcttg gctactttgt
      661 atggtgttgg ttctgccaat ttaatatggt taccaatagc atcaaaactt aaggctataa
      721 atcaacaaga agtaagtgaa agacttttgg tgatagaagc aatattatcc atacttgagg
      781 gtgataattc taatttaatg acagaaaaat taaaaatatt tttaaattca aaagaactaa
      841 ttgaacttga agaaattggt ggtagagctg aataatataa aaggatggaa tgtttatgtt
      901 gtatgatgaa gatgaaaaag aagaaaacaa tgagcgatgg cttttaactt attcagacct
      961 cataacatta cttatgattt tctttgtaat aatgtattct atgagtaatg ttgatgcgga
     1021 gaaatataaa caattatctc aatctctaaa ttctgctttt ggtggttctt ctggagttat
     1081 tgaaggtggt aatagcaaga tagaaccagt agttgaacca ggaagtaatg atttagatac
     1141 tttacaaaat gctaagttta aaaaaattgg tgaagaaatt cagaagtatt taaacgaaaa
     1201 tggtatggct aattcagtat cattaagagt tcaagataga ggattagtaa taagccttaa
     1261 agatacaata ctatttgata cagggaaagc tattgtgaag gataattcta gagataagat
     1321 tattcaaata ggtaagatgt taaatgaaat gaatagttac atgagagtag aaggccatac
     1381 agacaatatg tctataaaaa attcagagtt taagtcaaat tgggatttat cagttatgag
     1441 agcaaccaat gttgttcaac ttcttattga caatgcaggt atagcaccag ataaattatc
     1501 tgctgtagga tatggtgagt ttagaccaat agcagaaaat tcatctgaag aaggtaggtc
     1561 aaaaaataga agagttgata tagttttagt tgatagtaaa tatgataatg tagaaaatgt
     1621 ttcaaaggat aaatagttaa attagctgtc tcaatacaga attaattcta aaggagatgg
     1681 cttttttatg cgaaaatcaa aaatagatac atagtaagtt acctttttgt aggaatatat
     1741 ggtatcttaa atatataata tttaaataat gtataagctc aattaaaaaa tttatagagg
     1801 atggaaaata aatgggaaat aaaaataaaa atactaaata taaagataaa acaagagaaa
     1861 ggtataataa aaaagttgag aatttaaata aagaaaaatt aaataaaatt aataagcaat
     1921 ctaagaaagt agataagatt gatgatatta ttaataaatc tagtattgta ttatgtgtac
     1981 ttctagtagt gttttcattg ctttacttat ttaaactggt tcaacttaat ataataatga
     2041 tacttttagt aattacagta gctattcaac aaggattggt gtcatttggt gcatttagaa
     2101 ataaaaatta tgtaaaagct ttattttcta tatttgtaat agtatgtttc ttaattgctt
     2161 ttaaatatgt tgtaaatcct gtttaaatat atcaataaac gttctataat taatataaat
     2221 agtgaagtta cagttttaat gctattataa attttataat ttgaaggagt agattttatg
     2281 aataggtgta agtttgcaaa attaattatc acatcaatga ttgttttatt acttacagga
     2341 tgtagtttaa agaaggaaga taattataag ttagacccag aaaatccgac atcaatacaa
     2401 atttggcatt attataatgg acagcagaaa atggcttttg ataagcttgt taaggaattt
     2461 aatgacactg taggtgctga aaaaggaatt attgttgaag cattcagtca aggtaatgta
     2521 gttgatttat cagagaaagt tttagattct gcaaataaaa aagttggttc tgaagatgta
     2581 ccaaatatat ttgcagcata ctcagatact gcatatgaaa tggataaatt agggttacta
     2641 gtagatatgg ataagtacat aagtaaagaa gaattaaatg aatacataga cgaatatgta
     2701 gaagaaggca gaataaattc taaggatgag tttaaacttt tcccaattgc aaaatcaact
     2761 gaaattttga tgttaaataa aactgattgg gataaatttg caaaagctac aaattcaaat
     2821 ataaatgata taaaaacaat tgaaggatta gtagagacat caaaaaaata ttatgaatgg
     2881 acagatagtt taacgaaaga gcctaatgat ggtaaagcat tttttggaag agatgcttta
     2941 gcaaattata ttattatagg aagtaaacaa ctaggagtag aaattttttc tgttaaagat
     3001 ggtaaagtta cgctaaatat tgatgaaaaa gttatgaaaa aactatggga taatttctat
     3061 gtaccatata taaatggata ttttgcttct tatggtaagt ttcgttctga tgatgcaaaa
     3121 acaggtgata tattagctct tgtaggttct agttcaggag cagcatactt tccagataga
     3181 gtaatgctaa atgataatga gagttataat attgaaacat ctgtttttca agcaccacgt
     3241 tttaaaggag aaggaaaata tgctgtacaa caaggtgcag gaatggctgt aacaaaatct
     3301 actaaagaag aagaatatgc atcagtagaa tttttaaaat ggtttacaga taaagaacct
     3361 aatataaaat tctctattgc ttctggatac ttaccagtaa agaaaaaaac gaatgatttg
     3421 gatgttataa aagaagttat gaagaaagat aatttgagtt tgtctgataa agttgaaggt
     3481 tcaatagcct catctattga acagattaac agttgtaatt tatatactaa taaagcattt
     3541 gatggtggaa ctaaagctag acaaatactt gaatattcaa tgcttgataa agctaaagaa
     3601 gattcaaata aaataaatga attagtaaaa agtggaactt ctaagaagga tgcagtagca
     3661 caatttaata atgataaaaa ttttaaaact tggtttgaaa gttttaaggc tgagcttgaa
     3721 aatgctataa aaaaatagat gaattggcag ttagtgtgtt gacgagcaca aaggtatagg
     3781 tggaatgggt atggaaaaca atctaagaaa aaacaattca ataatgaaaa agatgatatt
     3841 tcccctaatt attgttatgc taattcaaac aagtttattt tgtgccacaa ttttatgggg
     3901 aggaactatt aagaaattaa atgataattc gtttgacatc ttaaatgaaa gagtaattaa
     3961 tcgtaaaaat tatatacaaa atgaaatgtt acaaagatgg tcaaatacaa gtgaaacgga
     4021 agctacaatt aattcctctg taaaaaaagt attaaatgaa aaaaatgcct taattgagga
     4081 tgtaggcaac aatgaagaaa ttaacaaaga tattataaaa agcatatcaa atgatttaat
     4141 atatcttttg agaaaaaatt ctgttacagg agcttttata atcctaagtg acaaaaatat
     4201 taacgataag tcaatagata gtaaaggtga aataagtagg acaggattgt atataaggga
     4261 tttagaccct aagtttaatc caaatgataa ttctgatttg ttaattgaga gaggttcatc
     4321 agatatagca agaagttttg gaatatctat ggacagttat tgggaaccta agttttcatt
     4381 taaaagtgaa aatgagcaag atggagatga ttttttttat aaaccattta gagctgcaat
     4441 tgataatcca aatgtatcaa gttctaattt aggatactgg ggaagtaagt ttttattgac
     4501 aaatgcaggt gataggctta tgacatatac agttcccctt atttatgaag atggaactgt
     4561 atatggagta cttggaatag atttaagtgt aaattattta agagaattac ttccatactc
     4621 agagataaat gggaataaaa agggtaatta tattttaggt gtagatagaa ataatgatat
     4681 ggcctttgaa aatgtaattt caaatggata ctcattaaaa gaaaaatttt gggatggttt
     4741 acattctaat ttagagcaga aggaatcgta taaaaatata tataagatta aaaataaaga
     4801 taatgaatgt ggtaatggca acatttatgc tagtgtacaa tacttagatt tatataactc
     4861 caatactcca tttgaaaatg aacgttgggc tcttttgggt attattgaag aaaaaagtct
     4921 tttgtcattt tcaaaaaggg tagagaaatt agttataata tctatagcaa tttctttatt
     4981 aataggtcta ataggtattt atattgcatc aagattattt acaaaaccaa ttgttctttt
     5041 agccaacaaa gttagaaaca gtaatccatc aaaaccagta aatcttgata agataaatat
     5101 atctgaaata gatgaattat cttcagctat agagttgctc agtgcaaatg ttgcagattc
     5161 ttcgtcaaaa ttatcacaga ttattgaaat ggtagatatg ccaattggag cttttgagtt
     5221 atacaaaaac gcagagaatg ttttttgtac aaaagaattt tttagcgtgt ttactactga
     5281 aatcaaattt gaagaatatg gatatatgga aaaaaataag ttcctgaaaa aattaagggg
     5341 actagataaa tatttgcaag aaagttatga aacagaaaat acatatatat ataagtttga
     5401 atctaaagat aaaaaactta agtggataag aatgaatatc tttgaagatg agctaaaggt
     5461 tcttggtgtt gttgttgatg taacaaaaga atttattgag aaaaggaaga tagaatatga
     5521 aagagatttt gatattttaa cgaatctttt aaataggaga gcttttcatt cacagataca
     5581 agaaaaattt aagaataaag atgaacttaa gatagcagca tttattatgt gggatttaga
     5641 taatctaaaa tatattaatg atacatatgg acatgatgct ggtgatgaat atattaggtg
     5701 tgctgcagac atacttaaga agtttatatc atggaatggt atagtatcta gactttcagg
     5761 tgatgagttt tatgtattta tatatggata tgaaagtaaa gatagtataa gagatattat
     5821 taattctgtt aagaaacaga tgaataatac cttattaaaa cttcatgatg gaacagaatt
     5881 taaaataagg gcatcagcag gaatttcctg gtaccctgat gactcaacca actatgatga
     5941 attaatgaga tacgcagatt ttgctatgta tcaaattaaa aatacaatca agggtgaagt
     6001 tagtgaattt gatattaata tatataataa ggattcattc ttattgagta atagagaaga
     6061 attaaacaag ttaattgatg gtcaattagt tgagtatgca tttcagccta ttgtagattg
     6121 taaaggtaaa gtttttgcat atgaagcact tatgagacct aaaataaaaa cttttagttc
     6181 gccaatagat gtcattagat tagctcgttc acagtctaaa ttatatcaaa ttgagcgtat
     6241 tacatggttt aaagcactta aatcatttaa aaaatacaaa gaaaaatttg gcgattgcaa
     6301 actgttctta aattctattc ctaataataa tttgtcaaaa gtagattttg aggaaattga
     6361 agatttatat ggtgaatatt taaatagagt agtactagaa ataacagaga atgataagat
     6421 taatgaagat tttattgaga aaaagaaagc atatatagac cattggaata tagaaattgc
     6481 tttagatgac tttgggacag gttacaacgg agatgctgta ctattatata taatgccaga
     6541 ctatgtaaag attgatatgt ctattgtaag aggtattgat aaagatgaaa acagacagaa
     6601 aatattaaaa aatcttatct catattctaa cgaaagaaat attaaagtga tagcagaagg
     6661 tgtagaaaca aaaggtgaaa tggaaacact aattaatctt ggagtagatt atatgcaagg
     6721 ctactatatt agtaaaccat catttatacc tgaagatata agcgacaaaa ttaaaaaaga
     6781 actcaagata tgtcatgaaa ataggaatga tgtggtttaa tagaggaaaa attaaattta
     6841 tttttatgaa cttttagttt ataattaaaa agaaaataat ataattataa atcaaggtgg
     6901 tggagctaat aatcacaaca aatatagata taagaaagtt aaatgaaaat caattagaag
     6961 cagttgagca tatagatggg ccttgcatga tacttgcagg gcctggttca ggtaagacca
     7021 gagtaattac atatagaata gccaatatgg ttgtaaacaa aaacatagca ccaacaagaa
     7081 tcttggcaat aagttttacc aaggcatctt caatagaaat gaaaaataga gctttgaatt
     7141 taagtgatga cataagactt aataaggtaa cctatggtac ttttcactct gtatttttta
     7201 aaattctaag atactttgaa agatacaact tagacagtat atttgatgaa aagtcaaagc
     7261 gaatgacaat caaggcaatc ctaaaaagtt taaatataga gaatgctgat gatgatgaga
     7321 atataggaca agttataaat gaaatttcct atgtaaaaaa tgaacttatg gataaaaatg
     7381 aatttaattc agaagtatta acaaaagatg agtttttaaa agtatacaac ttatacgaag
     7441 aacaaaaatc taaagttaat aaaatagatt ttgatgatat gcttataaga acttattatt
     7501 tacttttgaa caataagtct gcactagaaa tggttagaaa tgtgtataaa tatatattga
     7561 tagatgaatt tcaagatata aataaagtac agtttgaagt tttaaagtta atttgtagcc
     7621 cattaaacaa tatatttgca gttggagatg aagaccaaag tatatatgga tttagaggtg
     7681 ctagaccaga ttttttgctt gaatttgaac aatactttaa taatactaaa aaaataatat
     7741 tagatataaa ttacaggtct aaaagtgaga tagttcatac tgcaaataga cttatcgaca
     7801 aaaataaaaa tagatatgaa aaaatcatta agtgtagtca gggggatgga ggaagtgtta
     7861 cctatatttc tccgcatgat tcagaggaag aagccttata tattgccagg gaaataattg
     7921 acgaaataca aaaagattat gtagagtatt cagattttgc agtaatttat agaactaata
     7981 tacagtcaag agcattagta gatgtattta tggatatgag gattccattt gtagtaaaag
     8041 actcagtaat tacaatatat gaccattggg caagtcaaga catactagcc tatttaagaa
     8101 taggtattaa tccaaaatca aataaagatt ggttgagaat tataaacaag ccttttagat
     8161 atatatccaa agacagtata aatatggtta aggatgaaaa agactttata acagcattaa
     8221 taaataagtg taatcttcat cctaaacaag ttaaaacaat aaatgatttg gaaatagatt
     8281 taagttattt aaatacttta aatcctaaaa atgcaatatc ttatattaga actagtcttg
     8341 attatgatag atatgtttta gattattgta gcaacagaaa gataaagact aatggacttg
     8401 tagagatatt aaatgaactt gagagttcag caactaattt taatactgtt acagagtttt
     8461 tagagcatat tgatagagta aagactgagt taacggaaaa taacaagaat aagcagactg
     8521 agggtgtcat atttacaact atgcatagtg caaaaggatt agaatttaga aatgtttata
     8581 ttataggtgt aaatgaagga acaatacctc atgaaaaatc atatgatatt tgtaaggaag
     8641 agaaaaaaga agaacaatta gaagaagaaa gaagacttat gtatgttgct attacaagag
     8701 ctgaagaaaa gttatgtata agctctactt taaataagta tggtaagaaa gttgataaat
     8761 cattatttat taatgatata aaatctccaa cgaaaaaaga aattgacagt attggtgtag
     8821 gggataaggt ataccataaa aaatttcatg aaggagaaat aattaaaaaa gatggaatta
     8881 tgtttacaat aaagtttaaa gatagagagc gaatcttgga tttgaaaact tgtttattga
     8941 agaatataat ttatactatt taatttagaa tctaaattta gatagaaata taatgtatta
     9001 tttattatgt gcaagacaaa tagatatgtg taaaatgtat tatttaactt attagaaaaa
     9061 gaaataaggg tttaatatat tatttatagt tgtttagaaa aagcaacaat gtggaaaata
     9121 ttatttagta ttattaaaga aaagcaacaa tgtgaaagat attatttagt gtaatttaag
     9181 aaaaagcaac aatgtgaaag atattattta gtattattaa agaaagagaa acagtgtgaa
     9241 agatactatt tagtattatt aaagaaaaag caacagtgtg aaagatatta tttagtgtaa
     9301 tttaagaaaa agcaacaatg tgaaagatat tatttagtat tattaaagaa agggcaacag
     9361 tgtgaaagat actatttagt attattaaag aaaaagcaac agtgtgaaag atattattta
     9421 gtgtaattta agaaaagcaa caatgtgaaa gatattattt agtattgttt aagaaaaagc
     9481 aacaatgtga aagatattat ttagtattat ttaagaaata tctaaaaata tgaaatatac
     9541 tatttataat tacaaaacta atatcaataa atataaacag tagtatttag ataatttaca
     9601 agtaaaaatt attaaaaaaa taaaaaactt attgacaaaa atattataag gaagtacaat
     9661 tgtattaaca atttaaggaa acaaatccaa tgatagagaa agtagcatat atggatttac
     9721 agcgagttag gggttggtgt aagcctagca atgaagtcta tgtgaagaga gctctggagg
     9781 agattatcag aaactttagt atgataattg gtttacccgc cttaagggat tgagaggata
     9841 agtacttact tatcaaaaag agtggtaacg cggatataat tcgtctctta gctgtaaagc
     9901 taagggactt ttttgattta aaaataaaag tatccataca gcttaaatgc taacagtcac
     9961 aaattttgaa agtaatataa gtatttatca ataagagtgg taacgcggta aagtcgtctc
    10021 ttagtcatta aagactgaga gacttttttt gtaactcgaa acatttaagt attaaaatct
    10081 gagggaaatt ataattaaaa gagaggggta gttaaaatga aagtatttaa aaaattatta
    10141 agtttaggat tagtattagg attgacatta tcgctagtag gatgtagtgg tggaggagaa
    10201 aaaacaaagt tagaacaaat aaaagacaat ggaaaattag ttgttggtac tagtgcagaa
    10261 tttcctccat ttgaatttca taaggtagta gatggaaaag attcaataaa aggattcgat
    10321 ataatgttgg ctgaagaatt tgcaaaagag cttggtgtaa aggttgaaat taaggatatg
    10381 tcatttgatg gattaatagg tgctttaaat gcagaccaag ttgatattgt tcttgcaggt
    10441 atgtctccaa caccagagag agaaaagagt gttgattttt cagaattata ttatttaagt
    10501 agaaatgcag ttatagttaa agatgcagat atagacaaag taaaaactga agatgattta
    10561 aagaaactta gagttggagt tcaagcagga agtatccaag aagaatatgt agttaacact
    10621 ttaaaaatga caactacaaa atctttgaaa gcaatacctg atttaattac agaattaaaa
    10681 aatggaaaca tagatgcagt tgttactaat gaagcagttt ctttaataaa tgttaaaaaa
    10741 tatgatggaa taaaaatggc aaatactgaa gttgggaaag atgtaacaga aggtatggca
    10801 gcagcaatca aaaaatctga caataacaaa gattttatag aattattaaa caaaaagata
    10861 aaagaattac aagatggcaa gaagatagaa gaatttttaa atgaagcatc tactgaagct
    10921 gcttcaaatt agtaagaaag ttatgtggga gatgaaatta tgagtttaga ttttagtttt
    10981 ttaagtagat ttgggacttc ttttttggaa ggaacaggtg tgacagtatc aatttctctt
    11041 gtggcattat gctttggatt tataataggt ataattatct gtatggcaaa aatatcaaag
    11101 agcaaggtat taagagcaat atcatcaatc tatattgagg ttttaagagg gacaccatta
    11161 ttagtacaga tatatatagt atggtttggt ttacctcaat taggaataag attccctatg
    11221 ttgtttggta taccaagtga atttatagct agtgcatttg cattatcagt aaactctggt
    11281 gcatacgtgg cagagatact tagatcaggt atacaatcag ttgataatgg acaaatggaa
    11341 gcaagtagat cattaggatt aaattattgg tcaactatga gatatataat aatacctcaa
    11401 gctataaaaa atatattacc ttcattagca aatgagttta ttacacttgt aaaagaatct
    11461 tcaataatat ctgtaatagg agttgttgag ataatgcgta ctgctgatat agtaaaaaat
    11521 gcagcattta gagcattaga gccattaata gtagcagcag caatttactt tgttataaca
    11581 tttactctat caagattagt tggattatta gaaaagaaac tatctgtgtc taactagatg
    11641 agagcatgtt tagcatttag ggaaaacata gaatagtaaa aaggaaagtg ataatatgat
    11701 tacaataaaa aatttaagta aatcttttgg agatttaaat gtattaaaaa atatagactt
    11761 agaaatcgct aaaggcgaaa taatggttat agtaggtcca agtggttctg gtaaaagtac
    11821 acttcttaga tgtatgaatt tactagaaat acctacaggt ggagaaataa tatttgaagg
    11881 aaaaaatttg gtcgataaaa aaactaatat tgatgaggtt agacaaaata taggtatggt
    11941 gtttcagaac tttaatttat tcccacataa gactatttta gataatataa cattagcacc
    12001 aattaaatta aaaaagatga ctaaggaaga agcagaaaaa aaagcagaaa ttttgttgag
    12061 tagagttggt cttttagata aaaaagattc atatccatca caattatctg gaggacaaaa
    12121 gcaaagaata gcaatagcta gagcacttgc tatggaacca gatatgatgt tgtttgatga
    12181 gccaacatct gctcttgacc cagaaatggt aaacgaagtt ttggatgtta taaaagaact
    12241 tgctaaagaa ggtatgacaa tggcaattgt aactcatgag atgggatttg ctaaggaagt
    12301 tgcagataga gttattttta tagatggagg aagtatactt gaagataata ctccagaaga
    12361 agttttcgga aatccaaaac atgaaagaac aaaagcattt ttagcaaaag tgctataata
    12421 tataaaaagg atgttattga tattagaaat tcaatacatc cttttttagt gatggttaat
    12481 attaatttta aaattaaagt tatattaata ttaactttat ttttacgatt ttttgcagaa
    12541 aaaaaagagc tcggggtaag ctcttttttt ccaccgaatt aatttccgtt actaatccga
    12601 tttttaataa atataaaata tatccttatg aaagggtatt gggaatagat atattaacta
    12661 actagggtta ccagggggat aaccttaatt tattataaca aaatgcgaca caaaaatcaa
    12721 tatttttttt gaaataaatt ataaaagtta tttttataac aagtaagctt ataaatttaa
    12781 cttttatagt aaaaataagt atatgtataa tataatatat ttattttata taatatatta
    12841 ttttatcata tattgtattt tataatatat ttttgtaggg tatagtataa gtatattata
    12901 ttttactata aaaatttgta ataaagtgaa aaaactagct tttcatgaaa taatatttta
    12961 taatttaaga ttgtcttttt aataaagatt aacaaaaaaa atactataat tagtggtata
    13021 atagttagag ttgaagattt taaataaagg taggtgtaat taagttggaa atatacttag
    13081 acaatagcgc aactacaaaa ccttatcaag aagttataga taaaatggtt tatgcactta
    13141 atacggaata tggaaatcct tcttctgtcc atagaaaagg tgtagaagtt gaaaaagcta
    13201 taaaagaagt aagacaagat atagctaaat ctctaggagc gaaagaaaag gagatttatt
    13261 ttacatcagg tggtacagag tgtaataata ctataataag aggtattact agtttaaata
    13321 aaaaaagaaa aaatcacata atatctacta acatagaaca tccttctgtt ttaaatacat
    13381 taaaagattt agaagaagat ggttttgaag taacttattt agaggtcgga aaagatggga
    13441 aaataaatat agaggattta aaaaatgcga taaagtcaac tacatgctta gtaagcatga
    13501 tgcatgttaa caatgaaata ggaactatac agccaatagg tgaagttgga aagtatttga
    13561 agggtttaaa agaaaaaatt tatttccatg ttgatgctat tcagtcatat ggaaaaatta
    13621 actttagacc atctaaatac aatatagatt ttatgagtgt aagtgcacat aaatttcatg
    13681 gtccaaaggg aattggattt atgtatataa aagaaaataa tcgccttaag cctatgttaa
    13741 caggtggtgg tcaggaaatt ggaattaggt cgggaacaga aaatgtacct ggaatatatg
    13801 gtcttggaga agctgttaga atactaaaca aagatttaga tgctgttatt tcgaaagtag
    13861 ataacttaaa aaatatatta aaaaatgaaa taattgataa tatagaagat ataaaaatca
    13921 attctccaga agacggagta tgtcatatat taaatgtatc atttagaggg acaaaaggag
    13981 aagttttact tcattactta gagcaaaaag gtatttatgt atcaactggc tctgcatgtt
    14041 cttctaaaaa gaaaggtagt tacgtattaa atgctatagg tcttacaaat gaagaaataa
    14101 atggaacaat aagatttagt ttatctgata tgaatacaga agaagaaatg ttagaagctg
    14161 tgaaagtttt gaaagaatca atttgtgact taaggtcaat aatgaaaaga aaataaagaa
    14221 tactgtataa atagtgataa taaattagtt taagaggtga aatggtgtat aatatattaa
    14281 tagtaaagta tggagaaatt ggagtaaaag gaaagaatag atatatattt gagaataggc
    14341 ttataagaaa tataagaaat atgttaaaac caattggaag atttaatgta tataaagagt
    14401 atggaagaat atatgttgat ttagaagact atgattatga agaagtaatt gaagaagtta
    14461 gaaaagtatt tgggatagtg ggtgtgtgcc ctggagtaag agctaaaaaa gattatgata
    14521 cattaaaaga aatagcttta aaaatgttag aagaaaaaat agaggctgga tataaaactt
    14581 ttaaggtaga gtcaagaaga ggagataagt ctttcggatt gacttctcaa gaaatgagta
    14641 tggatatagg tggatactta ttatcaaagg taggagatag gattaatgtt gatgtaagaa
    14701 atccagaagt taaaataaag tgcgaataca gagaatttca tactatggtc tatagtgata
    14761 ctatacctgg atatggtgga ttgccacttg gaacgaatgg tagagctatg tctcttttat
    14821 caggaggtat agatagccca gtagctacat ggatggttgc aaaaagaggt atggaagtag
    14881 aggcagttca ctttcatagt tatccattta caagtgaaag gtcacaggaa aaagttaagg
    14941 atttagctaa aatactggca aaatactgtg gtagagtaag gcttcataaa gttaatatct
    15001 tagaaataca aaaagcaatt ggcgagaatt gtaatgaaga agaatctact attctttcaa
    15061 gaagatttat gatgaggata gcgcagagac tttctgaaaa aagacattgt gatgctttaa
    15121 ttacaggtga aagtattggg caggttgcat ctcaaactat acaaggactt acttgtacta
    15181 atgccgttgt agacttacca gtgtttagac cacttatagc aatggataaa tcagatatag
    15241 ttgatatagc caaaaaaata gggacttttg aaacatctat agtgcctgaa gaagattgtt
    15301 gtagtgtatt ttctcctaga aagcccgtca ctaaacctag attagagaaa atagaaaaat
    15361 ctgaaacagc acttgacatt gaaaaattag tacaggatgc tattgacaaa atagaggtag
    15421 aggatattga gttttagcat acaagttatt taattactaa attgaatatt gagtatatta
    15481 gtagttctgt aagtatatta gtagttctgt tgaaaggatt tatgtagaca atttattaat
    15541 atgtagtatt taaaaataag tactataatt ttatttaatg ggaatgatta ttatgaataa
    15601 aaagggtttt acactaattg aattgttagt agttatatct ataataggca ttttagttat
    15661 agtagctgtt ccagcattgt ttagaaatat agaaaaaagt aaagcagtta catgtctttc
    15721 taatagagaa aatataaaga ctcaaattgt tattgcaatg gctgaggaat caagtaaagg
    15781 caagaatgaa gtcatgaaag aggtattaga aaacaaagat ggtaagtact ttgaaacaga
    15841 accaaagtgt aagtcaggtg gaatatattc agcaacgttt gatgatggtt atgatggaat
    15901 aactggaata gaaagcattg caaaagtgta tgttacttgt acaaaacatc cagatggtgt
    15961 tgaaatggct agggatatac atcaaagtat gaaagatttg attgcatcat ttgcacaaga
    16021 cccttctata ataccaggag cctcaaaggg taatgatgat tttagaaaat atttattaga
    16081 caataaatat aaaaatgggt ggcctacaat tccagatgaa tttaaggcaa aatatggatt
    16141 aagtaaggat acactatata tacaaccata tgcatataat cctactaaat ctgatgctac
    16201 tgtagttgta tttgcaaata ataagactgg gggtaattgg tatacttccc tagtttacga
    16261 ttatgatgaa ggtagatggt ataaaggtaa aaatggtatt tctgttgcag gtaggtcatg
    16321 ggatgttgac acagatagtg ttaagtctgt aaaaacagag attcattcta aagagggatg
    16381 gggtccttta aattaatata tcatgtttta ttaatctggt attgattaaa ctatagaaaa
    16441 gagcagtttc tatagatgac gaataccaga ttttcattta tatatataat tgagatatat
    16501 taaaagtgtt tatattttta agtcttcaca tacaagctaa aaataattat aataatattg
    16561 taaagaaatt taattataag attaattttc tgaagattta gtatttgtac taagaaatac
    16621 ataaaaaggg gaatagatat gaataataat tttcaagaca accaaacaat aaatttaata
    16681 caaagtcgta gaagtatacg aaaatttacg acagaacaaa ttagtgatga gcaagtaaac
    16741 acattattac actgtgcatt tgcagcacct tcaggatgta ataaacagcc ttggcacata
    16801 actgttgtgc aagaccagaa acttttaaaa gagattagtg atgatacttt atctaggatt
    16861 catgaggtga gtaatgttga gataaataaa aactttaagt tattttatgg tgctccaacc
    16921 gttttattta tttcttatga tgaaagtagt tcatgggctc catatgatat aggaatactt
    16981 acagggaata taacaacagc tgcacaagca ctagggcttg gaagttgtat aataggaatg
    17041 gttagaggtt tatttacacc tgttgaacaa ggggatattg aaggtcttgt gagtgtattg
    17101 gataaagaag atgtaaaaga atcagagtca ataaagatga agtttgatac aaataaaaaa
    17161 tacagagaac tacttgatat accagaaggg tattctgtac catttggtat tgctgtaggt
    17221 attccagatg gaaatttacc aaatgctaga gaggtagttt acaaagtttc cagagtttag
    17281 gataaagtat tgcaagaacc aatcagttac ttgaagaatt aaatcagtaa tatacaaata
    17341 aattgatgga agaggaagct atttaaaaag tagtttagat ttttcgttgt aaaataatta
    17401 aataaagaat aaggtgataa gtattttatt tattatctta ttctttttta tttttgtttt
    17461 gtagaatgat aaaaataagg attaagtgta ataaaataga aaacaagtat gttaatttta
    17521 agtatatgct ttaaaattta tccaagttaa aaatttaaga tatcttttca gtataatgga
    17581 aaaaatgtca aaatattgaa atagggaaaa aatagtgata taataagaaa aaatagagaa
    17641 aaa
//
LOCUS       DAYAKB010000076        17625 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.076, whole genome shotgun sequence.
ACCESSION   DAYAKB010000076 DAYAKB010000000
VERSION     DAYAKB010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17625
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.076"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(584..1318)
                     /locus_tag="ACGI3L_002954"
     CDS             complement(584..1318)
                     /locus_tag="ACGI3L_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9198651.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            complement(2329..2967)
                     /locus_tag="ACGI3L_002955"
     CDS             complement(2329..2967)
                     /locus_tag="ACGI3L_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HFG9198652.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFTLWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(2970..3827)
                     /locus_tag="ACGI3L_002956"
     CDS             complement(2970..3827)
                     /locus_tag="ACGI3L_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198653.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            complement(3829..4203)
                     /locus_tag="ACGI3L_002957"
     CDS             complement(3829..4203)
                     /locus_tag="ACGI3L_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198654.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            complement(5365..6555)
                     /locus_tag="ACGI3L_002958"
     CDS             complement(5365..6555)
                     /locus_tag="ACGI3L_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFG9198655.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(6571..8526)
                     /locus_tag="ACGI3L_002959"
     CDS             complement(6571..8526)
                     /locus_tag="ACGI3L_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFG9198656.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(8543..10588)
                     /locus_tag="ACGI3L_002960"
     CDS             complement(8543..10588)
                     /locus_tag="ACGI3L_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFG9198657.1"
                     /translation="MKKITKERIENTMKKLFTSETFLEYQFISDCQISPDGGYTAFIV
                     KKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRNEKVKEAV
                     KNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRPIVEGLPE
                     EEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAITAPMFNV
                     VGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGFELYQNQV
                     ILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGAGQTTKVD
                     GEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCLGNGLPEV
                     YTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYEVGKKYPA
                     VLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQFGEIDYI
                     DFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRSIANWSGM
                     EGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYVDKCVTPTLFLHGEKDYRCYMQEA
                     FQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIKKDNIGQ"
     gene            complement(10975..11625)
                     /locus_tag="ACGI3L_002961"
     CDS             complement(10975..11625)
                     /locus_tag="ACGI3L_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198658.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            complement(12609..12782)
                     /locus_tag="ACGI3L_002962"
     CDS             complement(12609..12782)
                     /locus_tag="ACGI3L_002962"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198659.1"
                     /translation="MLKQMLENNLPIKIVSWDSEELYRNSLNSCSLGNYVPLIEYLSS
                     LEDFREVYKMLWK"
     gene            complement(12786..12941)
                     /locus_tag="ACGI3L_002963"
                     /pseudo
     CDS             complement(12786..12941)
                     /locus_tag="ACGI3L_002963"
                     /inference="COORDINATES: protein motif:HMM:NF014691.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            complement(13042..13722)
                     /locus_tag="ACGI3L_002964"
     CDS             complement(13042..13722)
                     /locus_tag="ACGI3L_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFG9198660.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            complement(13719..14645)
                     /locus_tag="ACGI3L_002965"
     CDS             complement(13719..14645)
                     /locus_tag="ACGI3L_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198661.1"
                     /translation="MNYIIETNQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            complement(14718..15635)
                     /locus_tag="ACGI3L_002966"
     CDS             complement(14718..15635)
                     /locus_tag="ACGI3L_002966"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9198662.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAMLQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            complement(15635..16324)
                     /locus_tag="ACGI3L_002967"
     CDS             complement(15635..16324)
                     /locus_tag="ACGI3L_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198663.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            complement(16732..17037)
                     /locus_tag="ACGI3L_002968"
     CDS             complement(16732..17037)
                     /locus_tag="ACGI3L_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198664.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
BASE COUNT         6021 a         2933 c         1918 g         6753 t
ORIGIN      
        1 atggtttaaa taatcttctt tactttgtat tatgatacat gctttaaata tttttacgca
       61 ctttatatta taatacatgc tttaaataat cttattcgct ttgtattata acacattatt
      121 taaatatttt tactcactct gcattatagt acattattta aatatttttc ttcgctttgc
      181 attatgatac attatttaaa tatttttact caccttgtat tatggtacat tatctaaata
      241 tttttcttca ctctgtatta tgatatataa cttaaatatt ttacctcact ctacaatatt
      301 atatataatt taaatatttt tcttcacttt gtatactaaa gtttatttaa agtattttct
      361 ttcccattat actatgctgt taaatatttt tcaactgaag tattgtagaa ccttaaaatt
      421 actataaaaa actatattct aaaatacttg taatactacg tatcaccctt aacacttaag
      481 tataatttta aagcaaaatt cttattactt atatttaatt ttgattctac atctttagat
      541 ataattttaa gtaatttaag aaattattgt aaatcatata gtactactca ataattaggt
      601 ttttcaatgt tccaattatg tttctttgat ataatccacc atgactaaaa actatcgttt
      661 ctatatcata attacttata tttttaatag catcttttaa ctcttgtttg ttgctgtgca
      721 ttacatcaac aggcttaagt tctccatttt ctacctgtaa caaatctcca gcaataagta
      781 ctttagactc ttttaaataa agacatatgt gacctctagt gtgacctcct gtatgtataa
      841 cttctatttc ctcacctaga ttcaattttt catggttatc taatgacaca tctactttag
      901 tatatgatga tttaaatcca agtcccataa catttagcat actaagcatc ttatcatcaa
      961 ttttatctac catttgttcc aacatataaa gtttaaaagg agtttcttct cctgttatat
     1021 agctgatttc acttttgtat gcatatactt tgatattatt cttagatttt tctcttagat
     1081 aatttatgtt tcctatatgg tctatatcat gatgagtaat tattatattt tttaacttat
     1141 caaagctcgt gttactttta ttaagagcat caattattaa atcaccttga cccggaagac
     1201 ctgtgtcaat aagtgttgca tcatcttctg tgtagattac aggaatatac ataactttat
     1261 cttcaccgaa tacatttgat gaaattttta aaacatctaa tccctttgct aaattcataa
     1321 tttttctcct tataattact taattagagg tcaatttaat taaagaaatt gagaaaatgt
     1381 agattttcct ctagttatat tttattaatt aaaaattatt aatacctagt atatcactta
     1441 agttgaagga ttactcgact tgattttttt gttattttat ggtatagtaa ttaatataga
     1501 agtaagtaat tgcaagcttt gcaattactt ttattttttt ctaataacta ttttattttt
     1561 gataattcgt ataaaattaa aagtaaagta atatggaaaa tatgaatata gaaaaacttt
     1621 aataagaaaa taaattatga ataaataaaa gaaacgcaat actgtatata gatgattatt
     1681 tagaaaaata aaatctcttt taataaaaat aagcttcaaa ataaactttt agttcataaa
     1741 gcttaggagg aactaaattg agtgcaagtg tatctactgt tcaaaataaa tagttcataa
     1801 agcactcttt tttatattaa atcaattata ttttcgtcat ttcagcaatg aaaaagaaac
     1861 ttatctctat tttgagacag cttcttttta ttaacttcct actttttatt agttttctaa
     1921 aattgaaaag ctttatttat aggattcctt agatttatat tttgacgata taatttttta
     1981 aaaacatctt aaaagatggt atacaataca cacaatcata ctcataattg aaaaataatc
     2041 aatggaaaat aaaattactg gatattatct attaaaaaat acaaattgat tcacaagaaa
     2101 catataatct ataatattat gatgttactc tctcgcacca agtaacttta ttttcaagta
     2161 accttttaaa ttcataccat ctaacttcac tcaataaaaa tggcaatata aatatgtact
     2221 ctatttttta cttttaaata tctgacaagc tttatatact attggaagta aaatacaaag
     2281 taaaacagcc caatctggta aatgtggcat ataaaagtcc cccttacctt atacaagctc
     2341 cttattacta aaaattttaa tagaaataaa cattgaagct aacagtataa ttaaacttaa
     2401 aaggaacaat acaatattca ctatcatgga tggatactga tatataaatg gaatttcaaa
     2461 attgctgtga gctatagtta atggtaatac aaatgatgaa gccatgatta tcaccacgaa
     2521 aaagaatttt gttgtttcat atcctaattt atattgaata ggcatataaa ctccataaat
     2581 aatagaactt attaataaaa caatcaaaat atatgttaag tcaaaagttc ctatttgtgg
     2641 aataagtaaa ttttcaatcc agtaaactaa tgtacaatag ataaatacca ttgcaaataa
     2701 aacatactta gattgaacta agccacgtct aggataagga gttgaacaaa gtaatacaga
     2761 tgcttttgaa tattgactct cctttaataa tagatactgg cacagcataa attctgaaaa
     2821 tataatggat agtacaaatc ccaatatttg tgcaaatgga ggtaaacgcc acaatgtaaa
     2881 taatgggatt cctattgcaa taaacaatat caacaataca tattttttta caatcagaat
     2941 atctttttta actaaatgaa tcaacataat tactctctcc tttcaatata tgcaagcata
     3001 atatcttcaa ttgtaggacg ctctattaaa atatctggca tatttttttg cacttcatta
     3061 atttttgagg taatccctat aaaaccataa cctgtaattt ctaaatttaa aaataatttt
     3121 ttgatttcat catttagaaa ttgaatatcc ccttttactt ttctatgttc gtccaataga
     3181 gtatcttttt cacgctctaa tataatacgt ccattgtcaa tcataacaat catatctgct
     3241 attttgtcta aatcagatgt tatatgagtg gaaaagaaaa caccacgacc acattttttc
     3301 atatatcctg ttagtatgtc aagtatctga ctacggatta gtgggtctaa accacttgta
     3361 ggttcatcca taattaaaaa ctcagcttta tgcgataatg ctaatgctaa tgcaaatttc
     3421 attttcattc cttttgaaag tgtatcaatc ttttgttttg ggttaagatt aaaacgcttc
     3481 atattttgtt gataatcttc ttcacaccaa ttatcatatg aaggtgcaat aatacttttc
     3541 atttctgcca ttgacaactc ctcatagaaa tatgaatcat caaatacaac tccaattcga
     3601 ttttttaatt ccttctcatt tccatcgaaa tctttaccaa agatttttat ttttccacta
     3661 tcacgcttta cgacatccaa tatcgaacgg attgttgttg tttttcctgc tccattaaca
     3721 cctataaatc cagttataca atcttctggt aatgcaaagc ttatattaga taatgaaaaa
     3781 tcggtataag tcttatttaa gttataaact tctaaaatat tttccatatt aatcctcctg
     3841 atatagaata tccatcattt cttgtaactc tatctgtgta attcctagtg cttttgcatc
     3901 cttaatcata tctgccattt tttgttcaac tatacgtctc tttgagtctc ttagtatttc
     3961 taaatttcca gttgaaataa atgttcctat tccaacttgg cgtgtaagaa agccttcatt
     4021 ttcaagttct tcatacactc gtctaatagt caaaatacta acttttaaat cattagcaaa
     4081 atttcttatg gatggcattg catccccttc tttcagttct tcagtaaata ttgcttcttt
     4141 aatttgctct ttaatttgtt ggtataatgg cttatctgat gtgttagaaa tgagcacttt
     4201 cattttttat cacccccttt ttatcatttt cagtgtgatg ttgttatata cacactatac
     4261 acttagagca cttttttgtc aatataaaag atgtaaaata ttactatgac aaaataaata
     4321 tgaatgaaat attagagatt gttgatagct ataaacactt tttaaaacca cataagatag
     4381 aatgtattaa atatttatta aaagtaagaa ttgaatatct aaaaaaaaga ggaatcctgt
     4441 atgaatgatt tgtttgatga taaattaagt tataaactat ttataaaaaa cataaaggaa
     4501 taaatccatt tctaattaca aacatactaa aaaatttaga tagtaataaa tagatagtaa
     4561 taaatagata gtaataaatg ggatgaattt ataagaattt ggatagagga aagagttatt
     4621 caagagtgta gactagaggt aaactctata ttaaaaaaat ttaaatttgg atattatgat
     4681 gcatggaata tttgcagaag taaccttgct ataagtatag aagatttttt tgattacaaa
     4741 agataatact ctaaaatgtg aggatttcaa cattcaatac tgtactttaa ataatatcac
     4801 tgcaaaatac catccacctt ttaccataat tgaataccct aattatttta aaaaagaaaa
     4861 cattagaaac agaaaacctt ggatatataa aataaaaaat actaacttct aaaacacgga
     4921 tactctttga taaataaaac aaaaaataat tttaataatt aaaattggct atctcaaact
     4981 agagataagt ctctttctca cttttaaaac gttgaaaata tattcgattt cgtacaaaaa
     5041 agagtgcctt agaactaaaa agttcacttt gtggcactcc cttttttctc ctctttttaa
     5101 ttttttataa aaattcttca aaaatattat taaataccct atattataca taaatcaaat
     5161 taaagttgca ttttagcaaa taaaaacaaa ttataactat tagcatagca aataaaaaat
     5221 ctgctctctt ataaaatcaa attataatta taaaaagaaa atattcttat aacaaattag
     5281 ctaatataaa attattttat aaattaatac tactttttag cttctcctat aaattaatac
     5341 cactttttta actttgaaac ctatctacaa cattggtacc ataagaccag ctaccacaat
     5401 agaaatcata caagccatac caccaactac cagcttaggc ataatcttag acatcaaata
     5461 tgctctttct tcttccgttt ctccaacagc attacacact tcatttgaaa ttaaatatgt
     5521 agttgggaat cccaacatct gacaaaaccc tactccaaaa gcaagaggtt tagaaccgat
     5581 aattttccaa cctggtaaca ccttcatcat aaggaatata ccaatgatag aagctgcaaa
     5641 catacccaca attggtacaa aaagactaat taaatctgtc aaagaaactt ttgctaaaga
     5701 aggaataaca gctgcaaaca caaccatgtt gataaatccc ttgatttttc ctttttccaa
     5761 aatgtctttt ggcacaatac caatacgtgt tacaataaca ccaacaacaa gacatacaat
     5821 agaataattt acatgaataa tctctgaaag ttcataccct agataagaga ataatgctat
     5881 aaaaaatata caaacatttg tagaataata tttatcgtat ttttcacaga aagcttgttt
     5941 tacttttgtg cctgtattct ctgcttcttt cttatcagta tcaacatttg ctaaatcaat
     6001 gccttttgat tttgcttcat gatattctac taaaagacgg tttgcctctt gtaacgctgc
     6061 tcttgaagct attggtgtac caataaactt ctgaattgca aatacaactg ttgctgtagc
     6121 tgctgcaagt gtcagtcctt tttctagtgc tgcttgtgtc ataatagtag tagcaggtaa
     6181 agctccattt ataactggta tgcttgtcaa tactgttgat tttccaaaca aaggaataca
     6241 taatgagaca cagactataa ctgctacaat tccaagccat gctgtcaata ctgttctcca
     6301 ttcgtctata aattgtttaa cattcaacat tgttcccata ctaaacataa tcattggaac
     6361 actccaacta gctgctgcgg tcatacctgc tttttcaata atatcagctg gtattgcttt
     6421 tgtgacaaat agaatcaaaa ataaaagtag tgtaacaaat acagctgata cttttgcttt
     6481 tgttttgctt gcaattaaat ccccaatagc aaataaaact aatacgacac taaaccataa
     6541 taacatatca ctcatagaat aaccccctta ttataaatat ctttcaaacc aatctacaat
     6601 agcatttgct cttgcaattc tattagatgg tcttccattt ctagacaatc catgtgtatc
     6661 tccgtggaac aaatacattt ctgtatctac accaagctgt tttaatgctg taaacatttg
     6721 gaaagtatcc cccataaaac atctataatc cctatcacta tgtaagaaca atgttggtgt
     6781 cttaacattt ttcacatatt taataggtga atgattccaa agaacctcct catgattcca
     6841 aggcgtctta tctccacaag tctgcttcat aattctatcc ccaaagtcaa taattaaaga
     6901 agctgtaatc aagttactaa tacctctttg agaaactgct gctttgaaac ggtctgtatg
     6961 accaattatc cagtttgtca tataaccacc gtaacttccc cctgcaaccc ctaagcggtc
     7021 tgcatcaatc ccaggatatt tttcaataca agtatctaca aattccataa gatgctcata
     7081 gtcaacatac ccccatcttt ctaccatttc taagaatttt tcaccataac cgtcaccacc
     7141 atgagggtta caataaatca catacattcc ctttgatgtt acacactgct tcaagtgtgt
     7201 aaacatatag ccatatgccc atttaggccc accatgaatg aacaatacag caggatattt
     7261 ttcgccttct ttagcatcta taggtggtat aacaaaacca tcaacttctt ctttattttt
     7321 tgctacaaac gtcaattttt caggtaatga aaccttatga gtatctaaat atggtttaga
     7381 aaaagcagtc atttttttca ttgtacctgt agtcatatca atgctatata tttctgctaa
     7441 ctcataatct ttcaacatta ctgtgtacat ggtgttgtcg taaatatcaa aagatgtaaa
     7501 agcatctact tttgtgatga tacgtatatt acctgtcttt gtatcaaact cattaaattc
     7561 tgtcatagtt ctgcaaattc ttgcaccaat aaatttatct cctataactt tattactacg
     7621 tccaccacca tatactgcat ctacatccag taatgtagca tacataccat ctggactagc
     7681 aatcatattt atttcactag tactcaaatc aagtataaaa atatcatgat tctgtgtaat
     7741 agaacggtct aatgttgaag cttgcaacat tactttatct ttgccaatat attttgccaa
     7801 acttatttgg tactttcctt gtggtacaag ttctttggtt tcaccactgt ctatatgata
     7861 ctcccaaagt ccagaaaaag gagttgcaca atcttcataa atctgaccag tatataaaat
     7921 tctgttttta tccgaagaaa catctatacc tgctacttca caaaattttg gtgtaatggc
     7981 ttttgttata ttttcacctt cttgatataa ttctaatgtt acacgtcttc tttgagaaaa
     8041 attttctcca tctcttataa aaggtttatc tgtaaatgtc caataatcta caccctctac
     8101 tgccctatct ggttctgatt ttttagaatc cgttggattt tttgttgtca gtaaccacaa
     8161 tttatttcca agtgatacag gtacgctaca agcttttgga atagaaaatg ctttttttgc
     8221 ttctcctcct tctatagaaa tagtgtaaaa atctgttgta cctgcttttg gcttatttct
     8281 tttagatgta aaaagtagtt ctgtattaga aatccaacta aatgatgtta catcttttgt
     8341 ttgagtcata tgtatttgtt tttctgtttt gatgtccatc acatataagt catgttcata
     8401 gcagtctttt tcctcgttga tatttgatat aatataagca atatgctttc catcaggtga
     8461 acaagaaata tcatgaggga atatatattc aaaaatatct gaactttcaa tctttatttt
     8521 ttccattttt atattctcct ttctactgtc ctatgttatc tttttttata tataccgaaa
     8581 accaatctag catttcaact aatctttgta gcttttgttt tggtctacca gaacgagaca
     8641 gttcatggtt ttctccttca aatagacaaa gttttgtagg acacccatga attttcaatg
     8701 ctgaaaacat ctggaatgct tcttgcatat agcatctata gtctttttca ccatgtaaaa
     8761 ataaagtcgg tgtaacacat ttatcaacat aagcaagagg tgactgtttc cattgaagct
     8821 cgtggttttc catatgagaa gcacctgttt gtcctttgca gaaataataa ccaatgtctg
     8881 ttgtaccctc catgccactc cagtttgcaa tagaacgctg agcacaagca acagcaaaac
     8941 ggtttgtatg accaattatc caattcgtca taaatccacc ataacttcca ccttcaacag
     9001 ccaattttgt tttatcaatg tctgtatatt tttcaagtac agtatctgta aattccataa
     9061 aatctatata atcaatttct ccaaactgtt tcctaatatc tgcaaaagca ttgccacgac
     9121 cttcagaccc ccttgggtta cagaagaata caaagtaacc tgcacttgta aatacctgta
     9181 tctcatgcat aaaatatggt ccatatgtca atcttggtcc tccatgaatc gccaatacag
     9241 ctggatattt tttccccacc tcataatcta ctggtttata tacgtatcct tgtatttccc
     9301 atttagaact tccttttgac tctatgtatt ctggcacaga aattttatat tcctctaaaa
     9361 tatggtcatt taaatgtgtt ttcttacaca atgttccatt ctctactgta taaacttctg
     9421 gtaatccatt tcctaaacaa cccacacata caatattgcc atcttttaca tctataaaat
     9481 caactgaacc tgtctgtgtt actttttcct gttttcctgt tggaatatgt attctttcaa
     9541 taatgcagtc catatctact gtagaagtgt aataaatata ttctccatct acctttgttg
     9601 tctgaccagc acccatttta acatcagatg ttactgtatt tccaatacaa tgatgttgat
     9661 gccctgaaag aagtttcatt tctttcgtat caatatcaat agtataaaaa tctccatttt
     9721 ctccatttcc ataagataaa gcatcagtta ggtttagtat cacttgattt tgatataatt
     9781 caaaaccttt tataatatac ttatcttttt ctaatataca gacatttgtg tttgtgtttg
     9841 tatcaaatac atagacccca tttttcaaac cttttacatc tttaaattct tgccctatat
     9901 ataagatttt tccatcactt attttcatac ctacaacatt aaacataggt gctgtaattg
     9961 ccttcaactc atttatatta ctatcgtata catataggcg ttttcttttt ctgctaatat
    10021 atccctcccc attgacagca taaggaattt ctttgaaatg ttcataatgt cttttgttat
    10081 aagcatttat ttttttctgt tgttcttctt ctggcaatcc ctctacaata ggtcggtcat
    10141 tgtcataaga atcaataact gcatacaaac cttttcctat aggattcaat ttaccacctt
    10201 tgatagggag tctaaaaagt tcttctgctt ctccaccatt taaagataaa gcatagtaac
    10261 tcatgcattg cttaccgttt ttgacagctt cttttacttt ttcatttcgc aaagcaggga
    10321 acaagatagt attttcatct tcccaggcat atgctccaac agagtttata gacgttattt
    10381 gttttaattc gccagtttta ttgtttaata tataaacttg gcttgtgtaa ccattctctt
    10441 tgatatcagc tttttttaca ataaatgctg tatatcctcc atctggtgat atttggcaat
    10501 cacttataaa ttgatattcc aaaaatgttt cactcgtaaa tagctttttc atagtatttt
    10561 ctatcctttc tttagtaatt tttttcaaac tccctaccac ctctttcatt ttttatttta
    10621 aatttaaaat aaaaaatttt aaatttaaaa taaaaaattt tataaaggtt atttttttag
    10681 gaagccttct ggcttccttg taatatttgt aatttaaagt atatttaatc catgcttaat
    10741 tcatacttaa tctatactta atctatactt aatctatact tagtccatac ttaatctata
    10801 tttaattcat acttagactt atttacacta tatttagatt atatttatta gattatattt
    10861 attagattat atttattaga ttatatttag attatgttta aactataatt agattatact
    10921 tagactacat ttagcaactt aatagataag tatatatagt aacttcaaaa cttattattc
    10981 atcttcacag aatcttttaa tagttccttg aatatgattt cttagtttat ctactgcttt
    11041 ttttgtatct ctgtcttcaa tgaattttaa tatttcaaaa tggtcttgta ctgttccttc
    11101 ataattacga ttttttaatg gtcgaattaa atagttcact actataaatc ttccttgtat
    11161 accaacatat acatcattta aaatctcatt atttgcccct tctacaatgg ctttatgtaa
    11221 ttccaaatct gctagtgcaa gttctacaga tttttcttga cgatagtact cctcgcattt
    11281 atcagagtat ctttttatta catctagctt ttgttgaaaa acctcttcct cttcttgcat
    11341 cattttttct aaagcatatg tttcaatcag tgttctcgtt tcacaaactt gttttaccat
    11401 atcatattca tactctggta cgtacacttt accatttgtc ataatagtaa gcactccatc
    11461 tttatttagc atttttactg cttgtacaac tggtgttctg cttacttcaa atttttcaca
    11521 aaggtcattt agtaatattt tttgacctac agagtattca ccacgaataa gactttcaat
    11581 aatcttatga tataaaattt catctaaatt tgactttact ttcactactc tcaccttatt
    11641 tctattcttt tgccatatta tattgaatta ctggacttta attactttta gtaatatttt
    11701 taaagtagaa attcttattt gatagtactt ttgtactaca atttaaatta ttgtactgta
    11761 aatcatgctc ttatactata gattaattca ttgtattgca aatcaagtta ttgtactata
    11821 gattaaatcg ttatacttca aattaaacta ttatactata gattaaacca ttgtacttca
    11881 aattaaacta ttatactata gattaaatcg ttgtacttca aattaaacta ttatactata
    11941 gattaattca ttgtacttca aattaaacta ttataccata gattaattca ttgtattgca
    12001 aatcaagtta ttgtactata gattaaatcg ttgtacttca aatcaagtta ttgtactata
    12061 gattaaatcg ttgtacttta aattaaacta ttatactata gattaattca ttgttctgca
    12121 aatcatgcta gtgtactaca aattaaacta taaatgttta ctatctctta ataatttgaa
    12181 taatatgtta caaaaagtat agcacctttt tatttttttc gcaataaata aaaaatttaa
    12241 aattttttat tttttatttt cttatattat caatttgaaa tatgaaagat taagactaat
    12301 agaattgatt cagttaattg aaaaaaatag gtacctttta tgaaaattct aatgataagc
    12361 atttttctga tgtaatggta aattataaat gataaaatta aaaatcactt ttagttttat
    12421 gaactgtccc catattaaga aacaactaag atacataaaa atagttataa agagatagtt
    12481 aaactatatc cactatttta tatagttaaa atagtgggta tagtccaagc taagaataac
    12541 taagaaatta gcgttaaata gcatagataa aaatacattt atatataaac tttttttgct
    12601 gcaaacaatt atttccataa cattttatat acttctctaa aatcttctaa acttgataaa
    12661 tattcaatta aagggacata attacctaaa ctacaagaat ttaaggagtt tctatacaat
    12721 tcctcactat cccaagatac aatttttata ggaagattat tttctaacat ctgttttagc
    12781 ataacaaatc tacctatgtg accattacca tcttgaaatg gatgtatcaa ttcaaatcta
    12841 taatgaaatt cagttataac tttaatagat acttcactct gactatagta ccattcaatt
    12901 aattcatcaa gctttggctc aacttcaaat ggttgtgcaa tattattaaa actctaataa
    12961 tattaataat agctgatata atagcaaatc attattatcc cgagaagata caattaataa
    13021 ctaccttcct atccacagta tctagtcaat ttcagtaact ttatgattta gtatataata
    13081 tataccaatc acagttatac caactataat aaaaacagaa atcaaactgt cttgagttgt
    13141 atttgtacca gctaaaataa attgtcttaa attgataaaa ataattgaac tgacaagggt
    13201 aacaggtatt gattttctta tcattccaac aacgaatgtc catataccta atgagcaaaa
    13261 tacaataata cttttaattg ctcctggtat ccaataagat aaaattgaaa tatgaaaatc
    13321 tccaataact aaattaaaat acttatccaa cacaacaacg aatgtaaaac aacagatata
    13381 tccaactatc attgatgata tcataagagt cgtaatcaaa agtaactttg ataaaataag
    13441 ttttttacgg tcaagtggat aagagaataa aatcaagatt gttttatttg tatattcatt
    13501 tattatatat gccacattca acacagcaaa taatataata tagtaaaaac agaaaaataa
    13561 actgattgtc ctaaatgtaa catcataatc atatattgaa gtagatttat cattcaatcc
    13621 agtaaagaca aaaaacatac ataagaaaat ccccagcatt gaaaataaaa aatatctttt
    13681 tagcccaact ttttttagct ctagtttcat taaatgtatc atagtgtttc tttacctcct
    13741 gtacctgtag tttggaagaa gtaatcttct aaagaacttt gtttacgtcc aatgctattt
    13801 ataccaattt gattttgaat aaatattttg gatatttctt ttacatcttt tcgtaaatca
    13861 tatatttcaa tacaactttc cgaagtaatt ttaaagtctt ttattccaaa ttctttttct
    13921 aacaagtatc cagcaagctc cacattatct acatctactt caacataatc tgtttgatat
    13981 ttgtgtatat ctgacataga aatttcttta ataagtttac catcttgaat aattccaata
    14041 gtgtccgcaa tttgttctac ctctgaaaga atatgactag aaataaatat agttattcca
    14101 taatctgtat ttaacttacg gaataattct cgcatttctc ttatcccctc tgggtcgagt
    14161 gcatttatag gttcatcaag aatcaataat tctggtttag taagaattgc tctagctatt
    14221 gcaagacgtt gtttcatccc taaagaatat tttgaaactt tcttgtttga ttgctttgac
    14281 aatccgacac attccaatac ctctgatata tgttctttgt tataataacc catatattca
    14341 cagtgtaaat caagattctg tttagcagtc aaattctcat ataaatacgg attttcaata
    14401 atagtaccaa tcttttttaa tatttcaaaa tcagtttctg ccactttctt accgaacata
    14461 actatttctc cagaatttgg cttaacaaga tttagcaaca ttttcattac tgtactttta
    14521 cctgccccgt ttggtccaac aaatccataa atttctccct ttttcacatg aatattaaca
    14581 gcattaacaa cagctttatc tttatatatt ttctttaatt gattggtctc tatgatatag
    14641 ttcatcatac tccctccttt ctaaaaacag tatacaaaat aaaattatct tttctctctt
    14701 ttaaatctaa cttttttcta acttttcaat tttactgtaa aaactgtttt tacattaggt
    14761 ctactattta cataaattga acctcccata gagtttacaa gcccttgaga aatagccaaa
    14821 cctaaaccat tgcctttttt tctgtcagca gtataagctc ttgtgaaaat atgctctttt
    14881 tcagtttcag aaatacctga acctttatcc tcaatatcta taaaaacatg tttttccttt
    14941 tcatatagtg aaatccctaa aaatctacca tctgaaccat attttatagc attatcaatt
    15001 aaatttttga gtatacgttg taatgcttct gtgtcaacat ttgcatatat aggtctatct
    15061 tcaatattaa cttcaacatt aaagttttct ttatctagca aatcataaaa ctctaaaata
    15121 atctcatgac ataattgtgt tagattggat ttttgaagat ttaatatcat atctccagat
    15181 tggatttttg ccatattaaa caggttattt attgaattaa caagctcatt tgaatttgtt
    15241 tgcatttttt ccacagttgc tctcattgaa gaagataatt cttctttttg actttgaaga
    15301 tataacattt caatataacc ctttaatact gtgatgggag ttcgtaaatc gtgtgatatg
    15361 tttgtaaata tttgcaacat cgctttttca cttctattat aattaatttg cctgctgtaa
    15421 aacttttcaa gaagtttatt tatatctact gctgtttctt ttacaatcga aatatcagat
    15481 ggtactaaaa tataattaat ttcatcatca tttgttatgt cacgaagtct tgaattgata
    15541 tacttataat cactttccat tttctttgat ttatttcgtt cttttaagta gagagcaaat
    15601 agtacaatcg aaattacaac taaaaataac tccattattc ttcctccatt ttgtagccaa
    15661 ttccccaaag agttttaata taattatttt tttctatacc atcagacaat ttatttctta
    15721 acctgttaat atgagtattt agcacatttt catttccata ataaggttct ttccaaatag
    15781 cgttgtataa ttgttccttt gaaaaagcac gtccttgatt agtcgctagt aatttaacaa
    15841 tttcaaattc tgtatgtgtt aagtttaagt caattccatt ctttgaaact acatattttg
    15901 atatatttat aatcaaatct ttatactgaa taaccatatc ttcagagttt cttgaactgc
    15961 tgtacactgt tgcacgtcta atattagctt taattcttgc aagcaattct acgattgaaa
    16021 aaggctttgt aatataatca tctgcaccaa gattaagccc tagcatttta tctgtgtcac
    16081 tatctttcgc agtagtaata ataacaggaa caacactcac acttcgtata tattttaata
    16141 cttcaaaacc actagacttt ggtaacatca agtccagtaa aataatatca aatgaataat
    16201 ttttaaatat ttcaatagct gtatttccat caatggcagt tttaacagag taattctcac
    16261 taatcagaaa atcgtatacc atttctcgaa tattcttatc atcttcaacc aataagatgt
    16321 ccattattat tcaactcctt ttcgtcagta tacttcaaat gatatattta ttaaaaaggg
    16381 ttgtcaataa ataactgctt atgatattgt atctgcaatt tggtgatact cttctaagtt
    16441 aaagttcttt tcaataagct ttattgaaaa aataattaaa atatagtata ctctcttatc
    16501 tttatctgaa atatacataa ttttctttta ttaacatcta caattaacta ttttatatta
    16561 taaaacacct tttaactctt gctaaaaaat attttataca taaaaaagaa accacattct
    16621 agttttatac agaacatagt ttctttaaaa ataatcaaat ttggatttta aataattaaa
    16681 aacaaacttt tatttgtttt taattttcca attttatagt agataattta gttaattagt
    16741 tcttaaatgt ttatcttctt tagtaaattt ttttcttatt aagaaatatg caactattac
    16801 aacaagttct attgctaaaa atacaccata agtagctata gaatctatgc tatctatgcc
    16861 atttctaaag aaaattaaag caattcctgc tgctataata cctacagcat ttttccctat
    16921 agaattttga ccaaaaccat aaaaagaagg gaaatttcct tttatttcaa tgaatgtcaa
    16981 gattaatcca atagctataa atagtactcc tacaacttcc ataatcatgc taggcatttt
    17041 gacccctcct tattaataat taactactac tataaaaata tttattattt ttataattat
    17101 attatatatg cgattacatg tttttggaag tatatttgga agtaatttca tatttattta
    17161 acttaatttt tttgtgataa aatacttcta atttttatat agatattatt ataaattttc
    17221 tagtttatgg agtcattcat tctataattc acaaatatgt attttttaat ctattaaagt
    17281 attcattttc tggcttataa gcatggactt cttatctata agcttggttt ttcatctaat
    17341 aagttattta ttctttaatc tatgagcttg atttttcatc tataagtcat ttatttttta
    17401 atctatgagt ttggtttttc atctataaat aagtcatttt ttaatctata agtttagttc
    17461 ttcatctata aatcatttat tttttaatct ataagtttgg tttttcatct ataaataagt
    17521 catttatttt ttaatctata agtttagttc ttcatctata aatcatttat tttttaatct
    17581 atgagcttga tttttatcta taattaattc attctctaat ctatt
//
LOCUS       DAYAKB010000077        17527 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.077, whole genome shotgun sequence.
ACCESSION   DAYAKB010000077 DAYAKB010000000
VERSION     DAYAKB010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17527
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.077"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(93..1892)
                     /locus_tag="ACGI3L_002969"
     CDS             complement(93..1892)
                     /locus_tag="ACGI3L_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HFG9198665.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(1895..2281)
                     /locus_tag="ACGI3L_002970"
     CDS             complement(1895..2281)
                     /locus_tag="ACGI3L_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9198666.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            2514..3191
                     /locus_tag="ACGI3L_002971"
     CDS             2514..3191
                     /locus_tag="ACGI3L_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9198667.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            3167..3628
                     /locus_tag="ACGI3L_002972"
     CDS             3167..3628
                     /locus_tag="ACGI3L_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9198668.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            3696..4475
                     /locus_tag="ACGI3L_002973"
     CDS             3696..4475
                     /locus_tag="ACGI3L_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HFG9198669.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(4722..5348)
                     /locus_tag="ACGI3L_002974"
     CDS             complement(4722..5348)
                     /locus_tag="ACGI3L_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFG9198670.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(5491..5748)
                     /locus_tag="ACGI3L_002975"
     CDS             complement(5491..5748)
                     /locus_tag="ACGI3L_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198671.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            6074..6586
                     /locus_tag="ACGI3L_002976"
     CDS             6074..6586
                     /locus_tag="ACGI3L_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198672.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSDCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            6841..7545
                     /locus_tag="ACGI3L_002977"
     CDS             6841..7545
                     /locus_tag="ACGI3L_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9198673.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            7542..8312
                     /locus_tag="ACGI3L_002978"
     CDS             7542..8312
                     /locus_tag="ACGI3L_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HFG9198674.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            8309..9088
                     /locus_tag="ACGI3L_002979"
     CDS             8309..9088
                     /locus_tag="ACGI3L_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HFG9198675.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            9140..9832
                     /locus_tag="ACGI3L_002980"
     CDS             9140..9832
                     /locus_tag="ACGI3L_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198676.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            9851..11275
                     /locus_tag="ACGI3L_002981"
     CDS             9851..11275
                     /locus_tag="ACGI3L_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFG9198677.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(11515..13983)
                     /locus_tag="ACGI3L_002982"
     CDS             complement(11515..13983)
                     /locus_tag="ACGI3L_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198678.1"
                     /translation="MKNYLSLSIKELKSQKFMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13986..14654)
                     /locus_tag="ACGI3L_002983"
     CDS             complement(13986..14654)
                     /locus_tag="ACGI3L_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198679.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            complement(14940..15467)
                     /locus_tag="ACGI3L_002984"
     CDS             complement(14940..15467)
                     /locus_tag="ACGI3L_002984"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013250.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFG9198680.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFSSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            complement(15683..16843)
                     /locus_tag="ACGI3L_002985"
     CDS             complement(15683..16843)
                     /locus_tag="ACGI3L_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198681.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            complement(16831..17505)
                     /locus_tag="ACGI3L_002986"
     CDS             complement(16831..17505)
                     /locus_tag="ACGI3L_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198682.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
BASE COUNT         6127 a         2297 c         2705 g         6398 t
ORIGIN      
        1 cttctatgtt tatataataa gccttgtata tgaatttaat tgataattaa tatgaaaatt
       61 atgtgaattt tttagaatgt acagtaaata tattaaggat tatagatttt tttgtcattt
      121 aatatggata atgttatctt agatgctgaa ctaccattag aataatcttt gctttgaata
      181 tttgtagcaa agaaataagt attttcattt ttttccacat aacctataaa ccaaccattt
      241 acatcttttc catttatatt ggcagtgcct gttttaccaa aaagtgatac cccatccttt
      301 tttgatatta acaatgaatc ttttactgtt tctatatttt tatcttcaaa tttaaactta
      361 tttgtataaa aactttcaag taattctacc tgttcaatag gtgatatttt taatgaagat
      421 tctagccaaa agtttgagat accacctgaa acatcataat tgccatatcc aatttgccta
      481 agataagttt gtatgttttt tagccctgtt tttttatcta gagtctgaaa gtaccagttt
      541 acggagtttt ccatagcaga aaataagtct tggtcttcat tccaagaact attagaatga
      601 tgctttccat cccaagggat atgtgaatta tttcttgtta ttatcccatt ttccaatccc
      661 aataaggcac tataaatctt ataagtagaa tttggagaaa ttcttgtttt acttttttct
      721 ttattgtaaa tatgatattg cttggatttt aaatcataca taacaaaact tccatcaaaa
      781 cctttaaaat actgacttaa gtcctcgtac acagtttgtt catttgtagg tctatatttt
      841 tcattgatat ctgccataat agatagtttg ggaatatttc caaatacaat taaagctatc
      901 aatgtaaaaa ttaaaatgct tttgaatttt aacgtatttg attcattatg aaaatccatt
      961 atcttcaata gtcgcttttt tatttgtttt tttgacccac caatatctga tgtaagtgta
     1021 agatttgatg gtcttgaaat attatccaca aagtttatta gagtttgtcc atattctata
     1081 tgactatctt tatcaagctt ttttaaaact gaaatatcac atgcaatttc acggtctata
     1141 cgcatttctt taaatgcata ccatacaaga ggattaaacc aatataatat ttgaaggaag
     1201 cacattatat aatttatcag tatatcttta tttttaaagt gttgtaattc atgaagtaag
     1261 atatatttta tatcttttaa agataattta gatatagact tatctggtaa tataatgtgt
     1321 ggtttaaagt atccaaatgt aataggtgta tttataatag gtgatttgca tagtataaaa
     1381 tccttattta taccaatatc ttttttacac ttttcaaata taaatactat ctcctcatct
     1441 cttaaaattt gtattgattt tttcatattt tttattttaa tgttgcaatg aatagtaata
     1501 gctatcatga ttaaaattcc aattatccat gatattagta ataaaatatt taaactatca
     1561 aaattaactt ggtttaggga tactgaaaaa tcgtttaatg catttgagtt attaattata
     1621 gaatttggac tattttttat catagaagtc ctattagtac tgcttccaag ttgattaaaa
     1681 gtatataaat agttaaatac atttccaaga ttaatatatt taagagggac aaatggaatt
     1741 attaacatta taagcaatat aaatccaata ttgtattggt actttgcaga aatatgtttt
     1801 ttaaatactt ttttggcaag taaaattaca gcaattaata ttgataaggt taatgtactg
     1861 agtaaaaatc gtataaagaa tggggcatac atatttattt atccccctta gtcgtccttt
     1921 tatttaagat ttctctcagt tcctcaatat catcttcaga tagtttatca ttttctaaaa
     1981 agtttagtac catagaatta agagtaccat tataaaaacg atttaaaaaa gaactacttt
     2041 ctgtagctac gtattcttct tctttaacaa gtggagtata aacgaatact ctgctatttt
     2101 tttcatatgt taaagctcct tttttaacta atctcaataa cattgtttga attgttttag
     2161 gactccatgt acttgtttct accaactttt caattacttc agtagtgctg ataggagcat
     2221 atttccaaat aattttcata acttgatatt ctgcttctga aatatgtggt aactttttca
     2281 tactatacct ccttctactt acatttgtaa tacataaagt atattatcat taatttagtt
     2341 tgtcaattat taaaaataat tcatttatag ttgattaaat aagcacatgt agttaaataa
     2401 aacttttatt taagctgtgt aagtatagct ttaaataaat ggtttatatt gacagctaaa
     2461 attatagttg atatacttat tgttgatata acaactaaaa aggagatata gaaatgataa
     2521 ttacagttat aaatggaagc cctagaaaaa atggagctac atcaaaagtt ttaacttact
     2581 tgtataaaga tatagaaaga ttaataccag atgtaaaaat taattatttt gatttaagtg
     2641 aggtaaatcc atcatattgt attggttgtt taaattgtta taaaatgggc aagtgtatca
     2701 atcaaaatga taaagtagag tatattcatg atataattac taagagtgat ggtgttatat
     2761 ttggtagccc aacttatgga agtagtgtaa ctggactttt caaggtgttt acagatagag
     2821 cacatatgat gcttgaaaga ttattgtatc gtaagccatg tatagcagtt actacatatg
     2881 aaaatgcacg tggttcaaaa gcaatttctt ttataaaatc catggtctta gattcgggag
     2941 gttatgtttg tggtagttta tctataaaaa ctggatttaa tcaaaatcct ataactgaaa
     3001 aagtagaatc aaagatacaa aaggtatcta aaaaatttat ttattgcata gaggaaaaga
     3061 aaaatccacc tgtgctttct caaatctata attttattgc tataaatgct gttttaaagc
     3121 caatggcttt taaagatatt gagcaatata agggaataat tgatagatgg gaggagcaag
     3181 ggattattta aatggaggta aaatgaaaga ttttgagaaa ctatatgaag ctacaactaa
     3241 gttagtaagt acttcgttaa aagtaaaaga tgatttaaaa aagatgttta aacaaaatgg
     3301 atatgatata acaactgacc attatgcgtt attaaggttt ctatgggagc aagatgggat
     3361 ttctcagata gatttatgtg aaaaatcatg taaggataaa tctaatacaa caagaatttt
     3421 agatgttatg aaaaataagg gattaattgt ccgtaaagta gatgttaaag atagacgtaa
     3481 gtttcaaata ttcctaacag atttaggtag agaattagaa gaaccattaa atgaaattgc
     3541 aagtatatat gcaacagaga catttaaatc tatctctgat gaagaattgc ctttgtttac
     3601 tgatattttg gatagaattg gaaagtaaat ataaatccta ttttaagaga ctttttaact
     3661 attgatgatg tagaaatata gaaagaggga taagaatgaa tagtaagatt tattattttt
     3721 ctggaacagg aaattcgcta gtagtttcaa atattttaaa agaaacgtta aatggaagta
     3781 aagaagttat acccttagct atacatagaa aagaaaataa tatagacata aatgaagata
     3841 tattggtaat tgtttttcct gtttattttg ctgatgttcc tgatatagta aagtcttttg
     3901 tagagaaatt aaattttaat attaatactc atatatatgc cattgccact tgtaatgggg
     3961 tagctggaca tagtttattt actatagata agttacttaa aaaaaggggg aaaaaattat
     4021 ctgctggttt tttaatcaat atgcctggaa atgctttgat aacacctcca gatgttgaag
     4081 aagaaagatt gaaaaatcag actaataggg tagctgagat tgcaaaatgt atcaataact
     4141 tggagattgg aaatatagaa ggaaaaaaca atttaaagtc acatatagat agtgttgtac
     4201 ttcgtttagt aggtaagaat atgcaaattg caactactaa attttttgca gaaaataaat
     4261 gtaatggatg tgggacatgt aaaagggttt gtcctgtaga gaatataagt atagttgata
     4321 aaaagccaaa gtggggtaat gagtgtgaaa gatgcctagc ttgttttcac tggtgtccaa
     4381 aagaggctat taatgtaaaa aaatcttttt taacgaatag gaagaagtat caccatccag
     4441 atattactgt aaaagatata tttttagata aatagatata tttgacttgt attaataatt
     4501 gttttattaa ataaaaacgt tagagatata aaagaaatat aaagtaatct tgtaaagagt
     4561 aatgttacct agactaaatg gaatagagat taaaaagaac aatataaata ataaattatg
     4621 ttaatagtat atagttacac taatataaaa taaaagtgcc tcataaatag aagtttttga
     4681 ggcacttttt attttatatt agtttttatt attttgtaat atcaaccgtt tataatctcg
     4741 aacatttttt ttatatcttc tgatgccatt tcaaattttg atttttcaat cagtatgttt
     4801 ccaccagtca taatatatga tggaaatact cttaaattat cataataaag ttcattatta
     4861 cgaagtttat atgttgaaat ggaagggatg acattctttt ttatatgctt tttagtaatc
     4921 atattaaaag atttttttgc aacatctccc attaacatta ctacctctag gtttttaaat
     4981 aatttaattt cttcttctaa aataggcata tgtaatttaa ttgtatcacg agttattgta
     5041 tattctgatt taggaagttt tactgcatta gttatataga tacccatatc taggatatca
     5101 tttatgttag atacttttat tcctgcactg tcaaataaag gaatagtagt ttttaaataa
     5161 tcagcatctt tatctacact ataaaaatcg tcattggtgt tagttgggac aacctcatta
     5221 atcattatag tttttatttt gtctgtttct attgttatat taggaagata ggatattatt
     5281 ctgctgtcat caaaaagatt gttctgttta ataaattcac ttaactttga ttttatattt
     5341 attttcatat aacgagtctc cttagtttta agctttaaat tactaaaaaa agctagtttt
     5401 aaagcacaca attttgaaaa tatagtagca tatttgaaag tataataaca tataaaacat
     5461 gacaacagaa tgtcatgttt tatagataat ctatcgcaac ttagaattta ttagagactc
     5521 tgcctgttca taatcgtctt tatgaacata aattaagtac tcataagaga aatcttcctt
     5581 ttggcctaaa ttgccaagtg ttatttcatt aaaaaaaggt tttttagagt aagcattatt
     5641 tttcacttta tacttatatt taattttatt tactgataat atattgcata tctcgttaaa
     5701 tctatttaaa gaatatcctc ggaaaagctc agctctattt aaaatcataa tgaaaacctc
     5761 cttttaaaag taatatattg aaaagcatag gagaaatgta ctataagttg ttataaataa
     5821 aaggtagcaa atttaaattg atttgtaaag tttttaagag tattatatta gtgataaaat
     5881 aaataatttt tagaatataa ctaataacaa tttaaaataa gtaacttatg taagaatcgt
     5941 aggaactacg gagatatcct gtagagaatt aataagacat atttaagtat gcaaaattct
     6001 attaagtaga aaccttgtaa ctttagtcat gtgagattca taaggatatt taagtattga
     6061 aaggagagtt taattgaaaa aaatatctca agaaaaaata agtacacata tccaagaaat
     6121 accacaggaa aaaattgaac agtggaaatc tttatatgaa aaatataaaa gtattttaaa
     6181 agtaaattct aagtctgttt tagaaataat agagttttta aagcgaaaat atgtaatagt
     6241 agaagaaact tcagaggaat ttaaacatgt agttatcaat aatattaagt taaacaagcc
     6301 tttttcacaa aagatttcca gtgataaaga attaaaacct attgtattta caattccaaa
     6361 tgaaggaaat gcaaaaaaat tgtacgatac tcaagaggaa atttatagtg actgtaagat
     6421 tattgtaggt atggaatttg aaacaggttg tgtttttgta gaaggtagtg atgagcttaa
     6481 tgatgaaata acttctttta aaggattaga taaatatgat ataaataatt attatttagt
     6541 agcaaactat attagatgtc taaagaaata taaattaata gattagtgtt tgattaataa
     6601 attagtgttt gatttaaaga ttatagagta aatttgaagt tagtgtgata atgaaactaa
     6661 gtttaaatct aatataactg taaaacataa acttaaatag agttgccaaa ataaaattgg
     6721 taactctatt ttttatttta aattttatta aaattagtag gtgttataga attgttattt
     6781 tttcatgtta gtattctctt agtaacagat ttaaggtatt acaagaaggg agaaattaat
     6841 atgaaagatt taattcttga aacaaaaaac ttatcaaaaa gatatggaga acaaatggca
     6901 gttaacaatg tttctctaca aattgaacga aatagtatat atggactttt aggaccaaat
     6961 ggagcaggaa agtccacaac acttaaaatg cttgttggtc ttcttcgccc aacaaatggt
     7021 cgtattattt ttgatagaaa gccttggaaa cgagaatctc ttgcaaaaat aggttcttta
     7081 atagaatccc ctgcattgta tggaaacctt acagcagagg aaaatttgtt agtacataca
     7141 aaaatattgg gaatacctaa agataaaatt tatgaagtgt tggaaatagt aaatttgaaa
     7201 aatacaggta aaaagagagc ttcacaattt tctatgggta tgaaacaaag gttaggaata
     7261 gctattgcac ttttgagtga cccagagttg ttaatactag atgaaccaac caatggtctt
     7321 gacccctttg gcattcaaga attgcgtgaa ttgattgctt cttttcccaa aaaaggtata
     7381 actgtaattc tttctagcca tattctatca gaggttgctc aagttgtaga taatatagga
     7441 attataaatg gaggacgact attatttcaa ggaatgcctg accctaatga aaatctagaa
     7501 gaatttttta cagatgttat tcttaaagga ggacaaaaca gatgaatgct ttacaatcag
     7561 aacttttaaa gtataaaaga acatttatgg gtaaacttat tgtttttttc ccagtgtctt
     7621 ttgcagcata tgcatttata atgcaatcaa cactcatgca aaatccatta tctcaaacaa
     7681 cttcttgggc gtggcaaaat cttttagcat taatttttaa ctggtggtca tttttatttc
     7741 tgcctattgg atttgcattg ttcgctactt tggtagcttt ccaggaaaaa aaagctggaa
     7801 attatcgtgc tttacgtaca cacaatgtgt ctcctatgac actttggatt aataaagtta
     7861 tagctatggc agtctacagt tttatttcaa cgctagtttt aatagtcgta acaattataa
     7921 ctggtttaat attgaaagct ggtccagttc cttttggaca gattataggg gcaagtattg
     7981 tatgctgggt tgtttctctt gctatacttc cacttcagct atggctagct acatggaaag
     8041 gtatgttcct aagtatggga gttggagctt taggtatgat atttggtgtt cttgctgcga
     8101 caaaaccatt ttggattgca gtaccttgga gttgggcagt tagaatggta tgcccaatca
     8161 tcaacataca tcctaacggt actatattag aagctggaga cccacttttg aatacttcag
     8221 tgattcctat tgggattgtt gtttctttgg ttgtgtttat agtattaaca gcacttactg
     8281 cagcttggtt caataggagg gatgacaaat gataaaacta ttatcatcag aatggcttcg
     8341 agcaaagagg acagctgtcc agtggcttac tctttgtatg cctattattt tttcattatg
     8401 tgtggttttt tatctcacaa ctaaatctgg aagtacacaa gaatttgctt ttgaaggatt
     8461 ttttacagta tggactgtat tcatcattcc tattggagta ggtattttag caggatttat
     8521 agtgcaggag gaagagcttg ctggaaattt taatggtttt ttatgtgtag gtatttctcg
     8581 tgtcagatta tatctgggaa aatttctttt tcttctgttt tgcctaacta tatgcacatt
     8641 tattgctacg ttgatacttt gcataggaat gagtattgca gtgccatctg gagcaacaat
     8701 atggttattc ctgtcagcag caggacttgt ggtgattggg acacttccac tattagctat
     8761 tcatctttgg gtgagttttg catggggtat gggtgcatct attggtatta gtattggtgg
     8821 aattttgatg gcagcaatac ttggattaac tagcgttggt gaaaaagtat gggcatttgt
     8881 tccatggaca tggccagtaa aactaggtat gcttccagga atttatttta ttaaagaagc
     8941 tggaactatt tcaactgagg cattttactc taaagtgatg caaacagcta gtatagagct
     9001 tatagtagta gcaataggtt tgattatatt cttgatagga ggcgttattt ggtttaaaat
     9061 gtgggaggga aggaaaagtt atgagtagac gaatattgtt ttaatactga ccttcccata
     9121 agagaaaggt ggtgttatat tgagtaaaat attgattatt gatgatgaaa tggacctagt
     9181 aatgctactt gaggatgaat tgaaggcaaa aggacatgaa gtgttgatag cttatgatgg
     9241 tcaggcaggt atagagttat caaaacagga gcctgacctt attatactgg atattatgat
     9301 gcctaaaatg aatggatttg aggtatgtca ggcaattaga gatgatgttt tatgcccaat
     9361 tatattttta agtgcaaagc aatcagaaac cgacaaaatc aaagggttga cctttggagg
     9421 ggatgattat gtaacaaagc catttggact gcgtgaactt atggcaagga ttgaagctaa
     9481 tctgcgtagg gaaaagcgtt cacagtatat caatgaagag aacaagagat ctactttgta
     9541 ttttgggaag ttatgcttat atatgaagga acgtgcaatt aaaattgatg gtaagaatat
     9601 tgatttaaca aaaatagagt atgatattgt tgaattacta gcactccatg caggacaagt
     9661 tttctcaaga gaacaaatct atgaaaaagt atgggggtgt gattctgaag gtgattcctc
     9721 aactgttgtt gaacgagtaa aaaaaatacg agctaagttt tctgctgtga caccagaaaa
     9781 agaatatatt tccacagttt ggggtattgg gtataagtgg aataaaatgt aaagagagag
     9841 aggttattaa atgaaaaatc aatcccttat tacccaattt agacatactt ttatttttat
     9901 tataatagcc agtatagttg ccacagtgat tacttatgta tttgctctct atttgtatat
     9961 tcattcctta aataaggata tctatccacc aaactattat gagcgacaag ttcctagaat
    10021 tgaaaaatac atcaatgaaa aaaacatagc tttgttatca caatcgaatg aagaaggttt
    10081 aaaaagaacg attcgtgggg atgatatgct atatcaagtt gtggataata atggcaatat
    10141 tttatatggt actaacccca aaaaactatt taaaacaaaa gaagaattat ttaataattt
    10201 tatcaataaa actgttcgta aaggtggtta tatccatact gttccaatca aaggggataa
    10261 tggaaagatt gagggtgctg ttattctatt ctaccaagtg aaaatcacct ttgcaaatat
    10321 tagagggaga tttgtatttg cagttattat aatggctttg ttttctccat ttctatatat
    10381 cgtgggtttt actagatggc tttctaagcg ctttgtaaag aatatcaatc aaccattaca
    10441 tctattgatt gatgcgtcca agaagataaa agaaaaggac cttgattttg aaatcgacta
    10501 ttattcagat aatgaactcg gtaaactttg tagtgccttt tctgaaatga aagacgaatt
    10561 aaaaggctct ttatctgcac agtggaagat ggagcaggaa cgtgttgaaa tggtggaagc
    10621 tctagcacat gatttaaaat ctcctctttc tattattttg ggatatacag atgcacttat
    10681 tggtaataat acagatgaca atgaaaaact tcataggtat cttacagtga taagagaaaa
    10741 tacagaaaaa agtgctgctc ttgtccaaaa gatgcaatat acgtctgact tagaaaagtc
    10801 aaatatacaa ttaaatcttg ttcctataaa tttacctgaa tttttgaggc aaaaggtgca
    10861 agactatgaa ttacaggctc atcaaaagga agttgaactt atattgaaaa tgcaggggaa
    10921 tatacaatcc ccaattcaaa tcgacgttga taggttgaca cgaatttttg ataatatcat
    10981 atccaacagt ctgcaataca ctccatcagg tggtaatatt agtattactg taaaggatga
    11041 aaaaaattgt atttcttatg agatttgtga ttctggtaga gggtttagct ctaaagattt
    11101 aaaaaaggct cttgataaat tttatcgagg agatgaagct aggcagacaa aaggtggaca
    11161 ttctggtctt gggctttaca ttgtcaaaca attagtggaa cagcttggag gttctgttaa
    11221 aatagaaaat tcaaaatcag gtggagcatg tgtgaaattt tggcatagca tttaactata
    11281 tattttaaat taaaggagag tgtctcaaag cgaaattttt aattcgtgag gcactctttt
    11341 tttgtgaagt taaatatatt ttcattattt cgacaatgaa aaaaggctta tctctatttt
    11401 gagacaggcc ttttttaaag cttatattat agttaaaaag atttattagt tagatttgaa
    11461 agaaaataga gacagtcatt gataatttaa tttatattat tatctgtaaa atagttataa
    11521 attgatatct atacagtcaa ttatattcat ctttttaact tttcttaacg gaataagagt
    11581 agctataata catgcaagta cagaaataat agtagcttgt aaaattgaag taattggtat
    11641 attagtgaaa tcaagctttt ctatagttgc catgtttatg ataatagcac tggcataccc
    11701 agcaattgaa ccaaatatag cagcaaaaat tccataataa acaccttccc ataaaaacat
    11761 tttatataag ctcctattac tcataccaat agctctttta actccaatct cattagtcct
    11821 agtatttata tttgtatgag ttgtgttaat gatgtttaaa gtaccaatca atcccacaaa
    11881 taatataact gcccatgcta gaaattctat ttgtttaaaa ctctctttaa gttgtttatc
    11941 tgattcaata tatgatatcc aatgagagcc aggattattt tcacaaatct gttcaataga
    12001 caatcttatt tgttctaatt ttgatttatc tttagcataa atatttatct ggttgaactt
    12061 gtttttattt gtcaaagtgt tataaacaga atcatataca ataacatcaa caccatttat
    12121 ccagccattg ccttgtaaaa agaacatttt atctactgta ctatatatat ctagttgttt
    12181 tttgttgatt gtgatactat ctttaggttt taaatttgta tatctagttt ttacacctgg
    12241 tgtagaaata gcaatcggat tttttataaa acagatagaa ccatttttaa agtcttctag
    12301 tatagaatct gtaatagaag gcattaagtc ttttaaagtt tgctcatcaa ttccaatgat
    12361 ttttaacatc tcaccactat tttcaaaatt tatatctgta tctatttcac cctgtttgta
    12421 ttcagagtac tttataaagg aagtgcgatt gacgtttttc attttagcta ttttatctag
    12481 tgttgattta tcaaaaccag atatttcatt tgttaaggaa aaatctcctt cttttaaatt
    12541 acttactgac ctagatacat ctaatacatt agagaactca ctcagtgcaa cgaatactgt
    12601 tatactcata aataatgata gtatagttat tatagttctt cctttatttc tttttaagtt
    12661 tagccatgct agatgtcttt caaagttttt tattgttttt tctcttttaa tttttctttt
    12721 gattttggta gtactaccaa ccatagcaat tttgggagag acatgtgaag catatattgc
    12781 tgatggtaat gctgaaataa atgaaaaaat caaagataca ttagtgctta atactaatgg
    12841 gaatatatat gctgttgtat ttttatgtat aagctcagta atttctttat tatcatttgc
    12901 tagaagtata tctggattta agatattagt gaccattcca gttatgcctt tagaagatat
    12961 aattccaatt acagctccaa taggtatggc aacagtacat aaaattaaga tttgtaaaat
    13021 aactatctta tatatctggt ttggttcagc tcctattgct cttaaacatc catactcttt
    13081 aattttcttt gtaacagaga tttttaaaat attataaatt acaagtccag aagccagtaa
    13141 aaccaataag gcaacaaata aagataccaa tataatcata gatataccat cactattaga
    13201 actattttca tctttttcaa actgtatctt aagagcattt aagtaaatcc aattatattg
    13261 aattgaattg tgagaaagat ttattttttt agctaattga tttactattt cttgaaactt
    13321 ttcttgctgt tttattttaa aatccaaaga ggataaaata tatctcttag gtaatagatt
    13381 ttctgatgta cctttaccta caataccatt tactatacca cttacatatc ctgtataatc
    13441 atcctctaaa atgccactca atttaaagtt agctgtgtaa ttatatggtg gtatggtatc
    13501 atttaaaagt gaaatatcta aattcatagg tatagtcact cctagtcttg gttttatacc
    13561 cataagcttt agtgtgtttt catctaaggc tatttcgttt ttatctttag gcaaatgtcc
    13621 agattttaat ttcattaatt ttgggtagtt agaaagtcct gttttatcat actcttttac
    13681 aagtacagag ataccagaat cctttatttt actactgcca atagttattg aagtaccagc
    13741 ttgataaact ctatcatctt tctttatgtc atcaacttga tttttagtga gttggtgaaa
    13801 ggatacatgt ctatcaccat taaaagaacg ggcttgttca attcttaaat tttgtaggat
    13861 accaattgac tgtccaacca cagttgtcat aatagttgat agtactattg ctataatgat
    13921 gaatgtagtc ataaatttct ggctttttaa ttcttttatt gaaagtgaaa ggtaattctt
    13981 catttctatt tcacctccat aagaacacca tcaataattg aaatttttct atcagcaagt
    14041 tttgcaattc tatcatcatg agtaattacc actaaagtct ttccaaactg ttttgaagtt
    14101 tttataagaa gattcataac ttcactgcca cttttactgt ccaagtttcc tgtaggctca
    14161 tcagcaaata ttatatctgg ttttgcaata agtgctctag caattgcaac tctttgttgc
    14221 tgaccgcctg aaagttcatg gggaagatga ttgagtctat ctgcaattcc aagtaatgat
    14281 gaaatttcat ttaaatagtc tttatcaggt tgttttttat ctagaagtac aggcattgaa
    14341 atattttcag atgctgtaag aacaggtaaa agattaaatt gttgaaagac gaatccaaag
    14401 gattttcttc taagtgcaga tagttctttt tcagtgtgtt tatatatatc tttatcatca
    14461 agtaacactt gtccagaggt aggattatct aatccactta aaatatgcaa aagtgtgctt
    14521 tttccacttc cagaaggtcc aattacagaa acaaattcac ctgagtttat ttctaaattt
    14581 acattattaa gtgctataac tttattgtta ttagaaccat atatttttga taattgtttt
    14641 gcttttataa tcataaaaaa cactctcctt ttctatataa gaagagtgta agttttaaaa
    14701 ctcaattttt tcccaacttt tagcttaaat ctaaaaagtc ttcactattt gcggataatt
    14761 cgcagtgctg ataagcagtt tcagtatcat ttttaattta aaatgtaatt tatgcactaa
    14821 aggctttaca atacaactct attgctttaa aactatttta cacataaact tgtggataat
    14881 tttttatgtt ttacttcctc attattatat aaattatttt tgtcacaaat tctaagttgt
    14941 cacataaata tactttttat atcacgattt aattcttttg attttatcat aattgctatt
    15001 tcttcaaaag aagaaagaaa agccacgata catatcataa ttcctgcaac atcaagacca
    15061 aagcaaatat agagtaatgg aaaagcaaag atagaaattc cagtgatttt attcatcaaa
    15121 gtatgaagcg atgaaaatgt gcgatactta aaaaaaccaa tactgtaact aatcaaccgt
    15181 aacaatgcta ttgcaacaat acaccaccat agatacatgg gaagagcaat attttttccg
    15241 acagtaacca aaattgtaac cgcaaaaatg aaatcagcaa tactatctaa ctttgcacct
    15301 attccacttt gttgtctcaa ctttcgggca ataagaccat caagtatatc actaattcca
    15361 caccaaaaat aacatatcca gaaaggcagt gaagagaatg tagaactaag cattagcaat
    15421 gcaaacacaa tacgagagaa tgtaatatta ttagcaaaac ttttaatata atcacctcca
    15481 aaattctaat ttcatactat tctacatatt taaatatata tttctattat tatttcaaat
    15541 gccttttgcc aaatattata attgaagcaa ctcttacaac ttctacaaaa tagtatatat
    15601 attggttgta aattgaaata cattttataa attctaaact aacaaatttt atataagaac
    15661 agtgaaagct tacaaaatca ttttaatttc ttgttgagaa tttagcagta attttagcac
    15721 tgttagtaga attattttca atagaaatag agccaccatg tttttcgcat aatatttttg
    15781 agatataaag acccatacca aagtgtgcat tgctgtcatt taaagtctta tctctataga
    15841 aaggtcttaa agctaatttt agagattcct tactaaatcc tataccatca tcttcaatta
    15901 caaaggtaag gagttcttgt tcaagatata taagtatgga tacattattt ctagcatatc
    15961 taaaagcatt cgatattata ttttcgacga ctctaagaat gatattttca tcaaaaaata
    16021 gatttatatt atttatttga cttttaagtg taaaagattt tccttcttgt ttagcaatga
    16081 tagatatatt ttcatctaag ttttctataa acttgtttat attcgacata gattttgaaa
    16141 caactaaatc ttctaatcgt tgagcattac tcatattttc tacatagtat tcaattctgt
    16201 taatatgctc agacataagt tgtgtggttg ataaaatctt ctcatcacta agcttacctg
    16261 ttggtatgta ttttgttaaa tagtttgagt aaccttttag aactgttagg ggatttctta
    16321 aatcatgaga aaaagcagca ttaagttgtt ttctatcatt aatcatagtc cacatcttta
    16381 tgttgttttt atttagttca gacctcattt tttcaaaagc attacataga ttacctaatt
    16441 catcattatt attatattct aagcaaaagt ctaaattgtt gttggatatt tccattgcac
    16501 ctttattgag tatttctatg ggtgttttta attttacctt gtaaaaaatt atatcagcta
    16561 ataataaaag tcctataaaa aagataagtg gaagtacaag ctgaagtatg ttgattatat
    16621 taagtaatgt tttatcataa tcactaaatt ggttcacatt gttttgaact atggttataa
    16681 tacctgtatt tataggtgtt tttaaatact tatcttgtat agaattatat agattattaa
    16741 gtaaaatgta tgcgaaagta gtaagcactg atgctataat tagtgaagat aaagtaagaa
    16801 caaagaaagc tttttttaat gacatattat ttattttatc catttataac caactcccca
    16861 gactgtttct atataatttt caagagtatg ttttgatagt ttgattcgta tttttctaat
    16921 gtgttccatt ataacatcac tatttccatt gctattgtat ccccagactc tatcatatat
    16981 tttttcttta tcaaatactt gtccaggatt catagagaga agctctacta tatcaaattc
    17041 cttttttgaa agtgaaatct gattattata tatacaaatt aacctttttt cgtaatctat
    17101 tgttaaatca ttataaaatt taattttagt ttgatttgac ttcctttgtt cacgtcttaa
    17161 atgggcagat actctagctc caagttcgtc taaatcaaaa ggttttacaa tataatcatc
    17221 agcaccagca cgaaaaccat ttatcttgtc agtattttca attctagctg taagaaatag
    17281 aatagggcat gatacataat ctctaattct attacaaact tcaattccat ctatttcagg
    17341 catgtttata tcaagtagaa tgatatctgg atttttagat atttttttta atgcgtcttt
    17401 tccactttga gcagtgtaaa cctcataacc attcatttca aagtaatctt ttaagagtgt
    17461 tattatacct tcctcatcat ctacgacgag tattttattg ttcataagaa tgctcccttc
    17521 taaatta
//
LOCUS       DAYAKB010000078        16669 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.078, whole genome shotgun sequence.
ACCESSION   DAYAKB010000078 DAYAKB010000000
VERSION     DAYAKB010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16669
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.078"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1334
                     /locus_tag="ACGI3L_002987"
     CDS             <1..1334
                     /locus_tag="ACGI3L_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9198683.1"
                     /translation="WKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYILKNYYQD
                     NFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDHFILLIA
                     CNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLLIDRANI
                     AAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYSLDDVNE
                     IEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWINKGYTP
                     VPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILIDIMKKI
                     KEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISKIVEMAK
                     AIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            1481..2227
                     /locus_tag="ACGI3L_002988"
     CDS             1481..2227
                     /locus_tag="ACGI3L_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198684.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            2227..4107
                     /locus_tag="ACGI3L_002989"
     CDS             2227..4107
                     /locus_tag="ACGI3L_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198685.1"
                     /translation="MDFRKFAYNNIVKNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGVII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAQITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            4226..5617
                     /locus_tag="ACGI3L_002990"
     CDS             4226..5617
                     /locus_tag="ACGI3L_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9198686.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            5724..6764
                     /locus_tag="ACGI3L_002991"
     CDS             5724..6764
                     /locus_tag="ACGI3L_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9198687.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            7253..7906
                     /locus_tag="ACGI3L_002992"
     CDS             7253..7906
                     /locus_tag="ACGI3L_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFG9198688.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKAAEKIDGIIDGMKF"
     gene            7982..8191
                     /locus_tag="ACGI3L_002993"
     CDS             7982..8191
                     /locus_tag="ACGI3L_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198689.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(8331..8897)
                     /locus_tag="ACGI3L_002994"
     CDS             complement(8331..8897)
                     /locus_tag="ACGI3L_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFG9198690.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            9058..9711
                     /locus_tag="ACGI3L_002995"
     CDS             9058..9711
                     /locus_tag="ACGI3L_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFG9198691.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGFSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(9869..10045)
                     /locus_tag="ACGI3L_002996"
     CDS             complement(9869..10045)
                     /locus_tag="ACGI3L_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198692.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            10573..11517
                     /locus_tag="ACGI3L_002997"
     CDS             10573..11517
                     /locus_tag="ACGI3L_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HFG9198693.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            11539..12165
                     /gene="hisG"
                     /locus_tag="ACGI3L_002998"
     CDS             11539..12165
                     /gene="hisG"
                     /locus_tag="ACGI3L_002998"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HFG9198694.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            12199..13248
                     /gene="hisC"
                     /locus_tag="ACGI3L_002999"
     CDS             12199..13248
                     /gene="hisC"
                     /locus_tag="ACGI3L_002999"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9198695.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            13251..13829
                     /gene="hisB"
                     /locus_tag="ACGI3L_003000"
     CDS             13251..13829
                     /gene="hisB"
                     /locus_tag="ACGI3L_003000"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HFG9198696.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            13831..14436
                     /gene="hisH"
                     /locus_tag="ACGI3L_003001"
     CDS             13831..14436
                     /gene="hisH"
                     /locus_tag="ACGI3L_003001"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HFG9198697.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            14433..15155
                     /gene="hisA"
                     /locus_tag="ACGI3L_003002"
     CDS             14433..15155
                     /gene="hisA"
                     /locus_tag="ACGI3L_003002"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HFG9198698.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            15137..15895
                     /gene="hisF"
                     /locus_tag="ACGI3L_003003"
     CDS             15137..15895
                     /gene="hisF"
                     /locus_tag="ACGI3L_003003"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HFG9198699.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            15923..16591
                     /gene="hisIE"
                     /locus_tag="ACGI3L_003004"
     CDS             15923..16591
                     /gene="hisIE"
                     /locus_tag="ACGI3L_003004"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HFG9198700.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDVIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         6624 a         1548 c         2891 g         5606 t
ORIGIN      
        1 tgtggaaatt aagtaatgct aaattaatag aacaacttaa aaaattggct tattatgatt
       61 ctttaagtgg aataaaaaat aaagaaaagt ttagaaaaga ttctatgtat attttaaaga
      121 attattatca agataatttt tacttagtac aattggatgt caataaattt aaatatataa
      181 atgagatgtt tggatatgct gaagggaata agatattaat tcatatatca caggttttaa
      241 ataataatac aaataaatat gaaatttgtg ctaggatgga taatgaccat tttatattgt
      301 tgattgcttg taacactgaa gatgaacttt taaatagatt atctaaaata aataaagaaa
      361 tttgtaactt aaatactact aactcatcta agtataaaat tgttatgtca agtggaatat
      421 ataagattac taaaaaggat gatattaaaa agattgactt gttaattgat agagcaaata
      481 ttgcagcaaa aagtaaaaag gaaaaatatg aacattcata ttcatttttt aatgaagata
      541 caagaaatcg attgtacaag gaaaaacgat tggaagataa tatgaataaa gctttagaaa
      601 aaggtgaatt tatagtatat tatcaaccta agtatagttt agatgatgta aatgaaattg
      661 aaggagcaga agccttgata agatggaata gtccagaatt tgggtttatt tcacctatag
      721 attttgtacc tttatttgaa aagaatggtt ttattgtaaa tattgatatg ttcgtgtttg
      781 aagaagtatg caaaacatta aacaagtgga taaataaagg gtatactcct gtaccaatct
      841 ctgtaaatat gtctagagtt catttatata gggataattt tatagaaaat ataactgatt
      901 tgataagtaa atacaatata tctcctgagt ttattgaact tgaactaaca gaaagtgttg
      961 tgtttgataa tttaaatata ttgattgata taatgaaaaa gattaaagag ataggattcc
     1021 ttatatcaat ggatgatttt ggttcgggat attcatcttt aaatctgtta aaagaccttt
     1081 cttttgatat tttaaaatta gatagaggat ttttaatcga aacaacagat acaaaacgtg
     1141 gaaaaattat tatttctaag attgtggaaa tggcaaaagc gattgatatt aaagtaatct
     1201 gtgagggcgt agaaacttat gaacaagtag agttcttgaa agagataggt tgtgataagg
     1261 ttcaaggata cttatttgct aaacctatgg tattagatga atttgaaaaa cacttaaact
     1321 ttaaatttga ttaatcatta ataattatta gactataata taccctaaca acttacttac
     1381 aaatatgtaa gttaattgtt agggtatttt tatggttaaa gtagtatatt cacgatatta
     1441 tggtattgta gtaaaaataa aaaattatgg agaatataaa atgaacatat tgagtattag
     1501 aaatatatca aaaacatatt gcggaaatat tccatttaaa gcattagata aggttagtct
     1561 aaatatagaa aagggagaat ttgtgtctgt tatgggacca tctggaagtg gtaaatctac
     1621 tcttttaaat ataatatcta cagttgatag acagagtgaa ggtgaggttg tattagatgg
     1681 atatgatgta agtaaattga aaggagaaaa acttgctgaa tttagaagga aacaacttgg
     1741 ttttgtattt caggatttta atttgattga cactttaact gttggcgaaa atattatgtt
     1801 gccacttaca ctagaggggg caagtatcaa agatatgaat atacaaacta aaagtatatc
     1861 taaattttta ggaatagata aaattttaga tagaaaaacc tatgaaattt caggaggtca
     1921 agctcaaagg tgtgctattg ctagagctat tataaataaa cctgccatac ttcttgcaga
     1981 tgagccaact ggaaatcttg attcaaaatc tactgatgat gttttgaaat tatttactag
     2041 gataaacaaa gaacaaaagg taacaacact tatggtaact catgaagcat atagtgcaag
     2101 ttattcagat agagtaattt ttataaaaga tggttgtata tatacagaaa taaaaaaatc
     2161 tgaaagcagt aattctttct attctgatat actagctgtt ttgtctcaaa taggaggtgt
     2221 aagatagtgg attttagaaa gtttgcttat aataatatag ttaaaaattt cagggcatat
     2281 ttagcatatt ttttaagttc tgttttttct ataatgatat tttttgtttt tgcagtgtct
     2341 atgttccatc caattataac aaaatctgga atgcagagtg gttctactgc atttatggct
     2401 cttatgactt cagaattaat aatattcggt tttagtctac tttttatatt gtactcttta
     2461 ggaaatttct tgaaatatag attgaaagat tttggagtat tgatgataat tggaatgagt
     2521 aacagacaac tgaaaaaatt gatattaatt gaaaatttga taataggatt tttagcagtg
     2581 atgttaggaa tattacttgg tttatcaatt tcaaaattgt ttttattgta tttaagcaaa
     2641 ctgttttata tgaatttaac tgaattttat tttccagtaa aagcaatgct attgactatt
     2701 gtatcattta tgattttatt tttgataaca ggaccaatga gcttaaaatt attgagtaaa
     2761 aagagcattt tagagctttt agtaggtaca aaaaagccta aaaaagagat aaaatcttca
     2821 aagctatttg gaataattgg tgtaatatgt cttatattag gatatgctat gatactattt
     2881 ggcaataagt taaaaataaa tggaggtatg tatacaacag cactattaat tactttgggg
     2941 atatttttat ttttttctca atttactatt ttgatattaa agtatttaaa aaataaagaa
     3001 aaattttata agaacaaagt aaatatgtta cttataagta atttgatata taaattaaag
     3061 gataatacac gattgttatt tttaataaca atacttttat cggctacttt agtagcattt
     3121 acaacaactt caacacttgt aagttctcaa ggagaagctt ctaaaaataa ttttccaatg
     3181 gtttactcat atttttcaga gcataataat gaaaaagaat atgaagaact acaacaaatt
     3241 agagaagcaa tcaaaggata tgattataag gagttaagtt ttcctgtact taaatataat
     3301 agggaagtct tactaagtgt aaagaattat aacaaattat caaaggaatt gggattagat
     3361 aaaattagtt caaagttaga aaaatatgaa ggggttataa ttcctagtag caattcacaa
     3421 gaacatataa attctttaaa acaattaaaa aattatagta taaaaaattt aaatatagaa
     3481 gtaaaaaaat caaaaaataa aataattttt cctacaggac tgtttagtaa agttgtagtt
     3541 ataagtgatg acttatacaa tgaagtaaaa ggtgaatttt caaaaattaa ttttcatgga
     3601 tttgattata aaaactggca aagcagtgca cagataactg aaaatttaaa agaaaaacat
     3661 tttaatttgg atagagaata taacaggtca tattttttaa cattaccaga tatgtattta
     3721 gtagagttac aacaaagtaa aattcttcaa tttatgggtg tttttatagg agtgatatta
     3781 tttatagcag tttttagttt tttatacttt agattatata cagacgagat agaagataat
     3841 gtaaagtaca aaaaactatc aaaaataggt ctatctttta aaaatatgaa taagattgtt
     3901 agtatagaga taggtacatt gttttttata ccgtatttta tagcaattat aaatagcata
     3961 atttctttac tgtttttaaa tcaagtatta aataatagtt ttaagttaga aaatttgggt
     4021 atattactac tgatatcatc tatatattca ctttattttt acttattaaa aaaaatttat
     4081 actagaaaag tttggttttt tgattaaagt ggtatataat agatatataa attaatattt
     4141 aaaaagtagt taatattagg ggagggcatt tgcacctccc ttgtaatatg tggaaaattg
     4201 aatattagaa gaaggaggag acttgatgga aaatcaacaa ttattaggaa cagaacgaat
     4261 tagtaaatta ctactaaaat attctatacc agctataata ggtatgttgg taaatagttt
     4321 atataatgta gtagatagaa tttttattgg aaatatacca ggggttggac cacttgcaat
     4381 aacaggtctt ggtgtaacaa tgccaataat gacaataata cttgcatttg ggatgttgat
     4441 aggtatagga actactacta ccatatcaat aaaacttggg caaggtaaag tagaagaggc
     4501 aagaaaactt ataggaaatg caatgacgtt atctgtaata acaggaatta tcataatgat
     4561 acttggaata ttatttgcaa ataaaatact tacattgttt ggagcaagtg aaaatacttt
     4621 aatatatgca aaatcatata tcaatattat attattaggt acagtagtaa atcttctttc
     4681 cttttcttta aaccactcaa taagagctga tggtagtcct aaaatttcag caggaataat
     4741 gatagtagga tgtttaacta atatagtttt agactggata ttaatatttg gattcaattt
     4801 gggaatacaa ggagctgcaa ttgctacagt aacttctcag gctcttacag ctattttaac
     4861 tatagggtat tatataagtg gaaaatcaaa cttacgattc agtaaatcta atctaaaatt
     4921 agataaaaag ctaataaaag cagtgtttgc aataggtatg tcgccatttg ctatgcaact
     4981 tgcagcaagt ttagttcaag taatatcaaa tattgcactt aaaactcatg gtggagattt
     5041 agctataggg gctatggcta ctatttcttc tattgcaatg gtatttttga tgcctatctt
     5101 tggaataaat caaggagcgc aacctattat aggtttcaat tatggagctg aaaaatatga
     5161 tagggttaaa aaagcatatt taggttcatt agtagtagct actataattt tatgtatggg
     5221 tatggtagta gttatgcttt tcccagaagc tattataggt atatttaata aagaccctga
     5281 acttatgaat atatctgtta atggattaag aatatactta cttatgttgc caattgtagg
     5341 cttatcagtt acaggaacaa actttataca atctatagga aaagcaaaaa tggctatgtt
     5401 attgagcctt ttaagacaag taattttatt gataccagca gtattaattc ttcctacatt
     5461 cttaggttta cagggtgtat ggacagctca accagtgtct gattttatag ctacagtaat
     5521 tacaggtata gttgtattta gagaattaaa aagatatact cctaaaactg aaaaattaaa
     5581 tgaaaatgaa agactaaacg agataactac tgagtaaaaa tataaattca gataattgag
     5641 caagaaattg caaaaaatac gattatatga taaaataaaa ccgctgtcaa ggataagaga
     5701 aattctaatt atggagtgat tttatggaat ttacaaagaa aagcaaatta aaaaatatgt
     5761 atgtaaacat gaatgtagct agaatgttgt ctaagataaa tgagtataag ggtagacaac
     5821 tgctttacaa aaaacaacca aaagaaattt tagaaaactt agaaaaaaaa tctttagtag
     5881 attgttctga atctacatac attggaaatc aaagagatag tagtaatttt aatctagaaa
     5941 agttgataag taatgaagtt acacctagaa gtagagagga attgagtatt gttgaataca
     6001 gagatgtggt aaaaactatt aacagtgctt atgagagtat tcccatcagt tcacaaacga
     6061 ttcttgagct tcatggatac ttatataaat tttcatctac tagaggagga agttataagt
     6121 cagataatga ttttattgaa cacaatttaa aacctagcga atttataagt attgattcaa
     6181 gtgtcaataa agttgaaaaa gctgtagaag aaatatgtga agcttataat acattgatag
     6241 aggaagatga aattgatata ttaatattaa tttctgcatt tgtgttagat ttcatattga
     6301 tacatccatt caaagaaggt aatataaaaa tggcgagagt acttatccta ttgttactaa
     6361 ataaaaatgg gtatgaagtt ggaagatata taagtttagg aaagatattt gatgatagtt
     6421 catatgaata ttatagtaat ttaaattatt tgaaagcctc aataggtagt gaaaaagcag
     6481 atatgaatgc atggattgag tattttttag agacgatatt aactgcatat gagaagctgg
     6541 atgatagttt aaatatatct gataagaaaa gacaaacaaa aactagtaga atagagaaaa
     6601 taataaattc tacccttgga tattttacaa aagaagatat aagagattta tgtcctgaca
     6661 ttccagaacc tactataaat agagttttta ataatctaag aaaacaagat aagatagaag
     6721 ttgttgcaag aggaagaagt gcaaaatgga agaaaaaata ttaaaaaatg tttagataac
     6781 taaaatggta tagtgtttta cactatacca tttttaatgt cattagcatg agcaataatt
     6841 taacaactta agcaatatca attttattta ttgattattt ttgaactgaa aaatggcgtt
     6901 atatggtata cctcagtggt aattaatttt ggatgagaag atataatatt acagaatata
     6961 ttaggagtat atgtagaaaa aatataataa aagtgtgagg cttagtaatt aacaaattat
     7021 gtggcttcac acttttttat aaaataaaga tacttagcag aagaatattt tagttgatat
     7081 gtttataaga tggtacttgt ttgggtaaaa gtataaatag taaaaaagta gaagtaatgt
     7141 gtataaaaac gtaagttaca ttctgtaata atagttattt tataattcaa caaaagaata
     7201 gaatgggtat atttgtgaaa taataatata aaataatctt aggagtgagc ttatgaagaa
     7261 aaaattatta tatataaatg taaattcaaa acctgaagac ttatcttcaa gtaaaactgt
     7321 agcaagaaaa tttataaata aatttatgga aaaaaataaa gattttgagg ttgaagagat
     7381 agacctttat aaagaacata taccaagact tgagtatcag tactttgaaa aaagaaatag
     7441 catagttagt gaagaaaatg ctaaaaattt agacgataag gatagaaaag aacttacaaa
     7501 gattagaaat ctttgtgacc aatttgtgag tgcaagtgta tatgtaatag cagcacctat
     7561 gtggagttta tcttttccag caccacttaa agagtatata gattgtataa ttcaagatgg
     7621 aaaaactata tcttttgaag gcaatgataa accacaagga attttaaatg atattgatag
     7681 aagtatggta tatatacaat cttctggtgg acacatacca tgggtgttga agccagttat
     7741 gaataaaggg ttaaattatg tggaaagtat tatgaaattt ataggaatta aaaaatttga
     7801 tgaattgtta gtagatggaa ctggaactag tgaagaagaa agacaagctg ctatagaaaa
     7861 agcagctgaa aaaatagatg gtataataga tgggatgaaa ttttaattat aatattttat
     7921 taaaaatata aaggaaaaac ctcttttaat gtagaaactt atattgaagg aggcgagaat
     7981 catgcgagaa gaaaaaagta atgaaaagta tgattgttat tggtgtaatc aagagaataa
     8041 tttctgtgta gaaataaaag ataatatagt catgatagat gatggcactg gtacgttaaa
     8101 acaagccgtt ttcatagggt ataaacaaat ccaaattaat ttaaactgtt cacattgtca
     8161 aaacttgaat agaataaaat taaatttgta gaattttaaa atggaaatta ttgaaggaat
     8221 taaaaataga aagtgttaat atttagactg aaaattatat tttatacaat aaaagtttat
     8281 ttaaataaca ttgtatttta atatttattt tcagtcttac tttattaaaa ttattttttg
     8341 gttatgtctg gaaaatatct gtctactaat ttttctgaaa tattttttaa ttggtcagcc
     8401 attgaagtca gacttaataa ggctatcaat aaatcatctt tattttctgg atttatacta
     8461 atattttcaa aattagactc tataaagtcc ggtatattct ttctttgatt ttcttttatt
     8521 aacatgaatt tttcgtaaca tgaaactaaa tctttttcac tgaaattatc cttttcatac
     8581 acaccatgta agattctttt aatttcttgt attgtaagtg tatttttcat agaataaata
     8641 attatcatct gtaaaatttg ttctttagta tacttttttc ccttaactgg tttgattaat
     8701 ccctctttgc tgtaattatt tatcatggtt ttagtaagaa ttttatcact ttcaaatctt
     8761 ttattggcag aaagcttatt gtcaattaga gaaataattt gatccatata taagtcaata
     8821 gatggaatat cgtttgaagt tatatctgca ttatttagtg tttctagtat tatagtatta
     8881 agttcattat tcatcatatg ttacctccat aatatatata atacactaaa ttagaaagta
     8941 aaacaatatt aaggcttgta aaaaaaacat aaagtggtat aattaaatat ataatatagt
     9001 aatggaaact atatttgtga atctgatttt taaaatacat aattgtagga ggacgaaatg
     9061 tatcaatttt ttttaaaggg tagagaccca ataagcagtt taactcattt tataggtgct
     9121 tgtttatctc ttttagcaac tataatttta gtttttcaat ctgttacatt acaggaaact
     9181 tctctcttga tgatagtatc tgtatcggta tttggatttt cactaattgc tttatatagc
     9241 gcaagttcgt attatcattt tttaaagggg acaccagaac aagaattgtt ttttagaaaa
     9301 gtagaccatg caatgattta cgtattgatt gctggctctt atacaccaat atgtctgaat
     9361 tttatggaaa aaaaagaagg cataatattt gttacagcaa tatggatagt tgcatttatt
     9421 ggtataataa taaaaatatt ttggatggat gcacctagat ggttatctac cagtatatat
     9481 ttacttatgg ggtgggcaat tgtttttgat ataaatgcat tcaattcaat tcctaaggat
     9541 tgccttagac tattaattat ggaaggtgta tcttactcta taggtgcaat tatttatata
     9601 attaaaaagc ctaatataag tcctgagttt ggatttcatg aaatatttca tatttttatt
     9661 atgataggtt ctttatttca ctttttagca gttttattgt atgttttata gttttaaaag
     9721 atttgattaa ttgatactaa aattctacaa tgaataaaat ggaactgcct tatatagatt
     9781 atatcttcga caataagaca gttccttatt ataaatatta aattctactt ataataaaat
     9841 tttgataaaa atagtccatt caaaatgcct attccataat tcctttaatg tacttttcat
     9901 ttacgacata tagtttgaat ttatgtacta taattatatc ctctaaattc tctgaaacac
     9961 taacaattct gacacatttg tttctaattt ctacaggtaa atctaaatca tttgttaaat
    10021 tcacatagtc atcatattta tacataaaat catcccttta cattaagata tacttattat
    10081 actatatttt aataagtttt tttaaattat tacaattttt cccgaaattt cattttttat
    10141 acataaaatt tccaaattag gtaaagatta aattttttat tgtataaaca aaagttacat
    10201 ataaaatatt ttattcaatt ttttaaataa ctattgccaa tttttgaaaa atatattatt
    10261 attaatagta acaaaaaact gtaaatttag aatattaata aaaattattt gggaggaaat
    10321 tatcatggtg agattaaata tagtaaaatt aaatacaaaa ttaaatcatc accatcatca
    10381 tagattaaag ggattgtaat atgaaattaa ttcatagaca caagccctgt ttttagtgta
    10441 attggtcttg tatctatgat gggaagtaat tttaagagaa aattatagcc atataggtat
    10501 aaagcctatg tggctttttt attgttttaa atttgcaaat ataagagtaa atttaatgaa
    10561 gagggtgaga atgtgaaatt tttgaggatt gaagatgagg ttatttattc taaaaaaaga
    10621 tataaattaa aaagggaaat agataaactt tttttggatg aagaatattt tcaaatagaa
    10681 ccacaattat ttgaagaata tgatgaattt acaactataa ataataaaat tccagaagaa
    10741 tctatggtaa aggttgtaaa tggaaaagta atggtactta gagctgatat aactacaagt
    10801 ataataaaaa gccttgtacc aagatgggaa gatggtttaa agcttaagct tttttataat
    10861 tcatcaatat ataaaaataa aaatacagtt ggaataaaag agataagaca aataggttgt
    10921 gagtatctag gagaagcctc tgtagaagca gatagagaag tagtgaaatt agctcttaag
    10981 atacttgaaa aatacaataa taattttatt ctagaggttg ggagtagcaa gtatattcat
    11041 ggtttgttag aagaattaaa tttaaataag aattgtgaaa atcaaattaa aaatttacta
    11101 tatacgaaga acactcatga actaaaagta tatattgaag aattaaaaat taagcgtgaa
    11161 gtaaaagagt tattatcaaa tattttaagt ttacaaggga atttatataa tgttattgaa
    11221 aaatcaaaca agttctattg taataataag atgaagcaag ctcttgaaga attaaagcaa
    11281 gtaaataatt taattgagga atgtaatttt ttagataagg ctagatttga tttatcaatg
    11341 attactatgc ttgactatta tgaaggaatt atgtttagag gatactaccc aaactcatat
    11401 aaagaaattc ttagtggcgg aagatatgat tctttaacta aagagtatgg aaaagaaatt
    11461 ccagccattg gatttacact aagtgttgat gagttaatga agtatgtata taagtaaagt
    11521 ttagaaggag ggattgcttt ggattatttg actatagcac tagcaaaagg acgaattgaa
    11581 ggggaatcat ttaaaaaatt taaaaaaatg ggtctaggag acagtataga cacagatacg
    11641 agaaaactaa tttttaaaga tgaagaaaat aaaattatat atatacatgt aaagccatca
    11701 gatgtagtta catatgttga aaaaggagtc gctgacctcg gtatagcagg taaagatact
    11761 attttagaaa atgagacaga tgtatatgaa atatatgatt taggttttgg aaaatgtaaa
    11821 tttgctgtag caggattaaa gggagatagc atatatagag aagatgaata tttaaaagtg
    11881 gcaacaaagt atcccaatat agcaaaaaag tattttaaag agaaaggtca aaaaattgaa
    11941 ataataaaat taaatggttc tgtagaacta gctccaatag tagggttgtc agatgtaatt
    12001 gtagatatag ttgagactgg caatacactt aaagcaaatg gtcttgaaat attagaagac
    12061 atatgtaata taagtgctag aattatatca aatagagcta gctatagatt taaatatgaa
    12121 caaattcaga atataattcg tttatttgaa gaacttgata attaaaatat aattgagctt
    12181 tataaggagg gatttaagtt gagagaaaaa gaaagcataa gagagttaag gggatatgaa
    12241 ccaaatcacg taaactgtaa agtaaaactt gatgcaaatg aaggaagtaa gaggttgttt
    12301 aaatacctta ttaaagaaat ttcagatagt gatatagatt taaatttata tcctgaagat
    12361 tcttatagtg atttgaaaga atctataata gattacataa atatttctgg agtaaataag
    12421 aaaaatcttc tagtaggaaa cggttcaagt gaaataattg atttaataat acatactttt
    12481 gtagataaag atgaagtaat attgagtttc tctccaagtt ttagtatgta ttctatatat
    12541 agtcagataa atgggtctaa atttataggt gttgaaagtg atgaaaattt agttataaat
    12601 atagataatg tgattgaaaa agtaaaggag aataatccta aaatagtaat tgtatgtaat
    12661 cctaataatc caactggaac aatattaaag agggaagaga taataaagct tttagattca
    12721 actaatagtc tagtggtttt agatgaagca tatatggatt ttggagaaga aagcatgtta
    12781 agtgatgttt ttaagtatga taatctaata gttcttagaa ctttatcaaa ggcatttgga
    12841 ttggctggaa taagaacagg atatatgtta tctaatagta gtttaataaa ttctgttgag
    12901 aaagtaagac ctccatataa tttaaattca ttatcagact ttattgctac aagagcactt
    12961 agaaataaag atgtggtaaa ggcttatata aaggaagtaa aagaggaaag agaagtttta
    13021 tatgaagaaa tgattggtat gggaattaaa gcatacaaat cacaagcaaa ttttatatta
    13081 ttttattctg aaatcgaaaa tttatcacaa aaacttattg atagaggtgt tttaataaga
    13141 aaatttggtg gaaagttaga aaattattac agagttacaa ttggtgataa agaagaaaat
    13201 tctatgtttg ttggagctat aagagatatt ttgaaaaagg agaaataggt atgagaattt
    13261 ggaaggtaga aagaaatact cttgaaacac agattttagt agaattaaat attgatggtt
    13321 ctggtaaagc tgaaatagat actggaatag gatttttaga ccatatgctt accttaatgt
    13381 catttcatgg caagttcgat ttaaaagtga tttgtaaggg tgatacatat gtagatgacc
    13441 accatagtgt agaagatata ggtatagcta taggtgaagc atttaaaaat gcactaggtg
    13501 acaaaaaagg aatacgaaga tattctaata tctatatacc tatggatgaa tctctatcaa
    13561 tggtagcaat agatataagc aatagacctt atcttgtatt taatgctaaa tttgataccc
    13621 aaatgattgg tagtatgagt actcaatgct ttaaagaatt ttttagagct tttgtaaatg
    13681 aatcgagagt aacattacat atcaatctct tatatgggga aaatgaccat cataagatag
    13741 aaagtatttt taaagcattt gcaagagctt taaaagaggg tagtgaaata gtttctaatg
    13801 agatagcatc ttcaaagggg gttttgtaga atgaatataa tagtagacta tggtcttgga
    13861 aatatagatt ctgtgtctag gggttttaga aaagctggaa tagaaactaa aatttctagt
    13921 gatatagatg aaataaaaca ggcagattca cttatacttc caggtgttgg agcttttaga
    13981 gattctataa gtgccttaga taaactagga ttgataccaa taataaagga gcatgtttct
    14041 aagggtaaat ttatgatagg tatatgtcta ggaatgcaat tactttatga aaaaagttat
    14101 gagtatggag aatatgaagg attaggactt ataaaaggaa gtattgataa actggatata
    14161 agtttaaaag tgccacatat gggatggaat aatctaaaat ttaataaggc aaatgatgat
    14221 atacttaaat atataaatga agatgattat gtatacttcg ttcactcata ttatgcaaat
    14281 tcatcaaatg aagaactaat tgcattttca gaatatgaaa agaaaatccc tgctattgtt
    14341 agaaaaggca atgtatatgg tatacaattt catcctgaaa aaagtggaga agtagggtta
    14401 aatatattaa gagcatatgg ggagatgata aaatgataat atttccagca atagatataa
    14461 aagataataa gtgtgtaaga ctcacacaag gagaatttga caaagtaaat gtatattatg
    14521 ataatccatt agaagtagca tataaatgga aaaatgaagg agcagaatat atacatatag
    14581 tagatttaaa tggtgctaga agtgaatttg gtgtaaatac aaaaataatt gaggacatag
    14641 caaacaatat agatatacct attcaagttg gcggtggagt tagggataag gaaaaagtca
    14701 aaagtttaat aaatgctggt gttactagag taatattagg tagtatagcg attgaaaatt
    14761 tgaatttagt tgaagaattg gtcaatgaat ataaagagaa aattgtagtt tctatagatg
    14821 ctaaagatgg aaaagtagca gttaggggat gggaagttgt aagcaatgta gactcattaa
    14881 cattatgtaa acaacttgaa aagataggtg tacaaactat tgtttataca gatatatcaa
    14941 aagatgggat gttgcaaggt ccaaattttg acatatatga aagaatagca aaggaaacat
    15001 cactaaatgt tattgcttct ggaggcgtaa cttctataga agacgtaaaa agactaaaag
    15061 ctatgaactt atatggtgca ataataggta aagcgcttta tgataaaaag atagacttta
    15121 aggaggcaca acaattatgc ttactaggag aataatacct tgtctagatg tgagaaatgg
    15181 aagagttgta aaggggaaaa aatttaaaga tatagtagat gttgatagtc cagaagtact
    15241 tggaaaattt tatagtgatt gtggtgcaga tgaacttgta ttctatgata taactgcatc
    15301 aaatgaagag agaaagacat ctttagaatt tgtgacaaaa gttgcagaaa atataaatat
    15361 accattttgt gttggtggag gagtaaataa attagaagat ttcactgata ttttaagaaa
    15421 aggtgctgat aaagtttcta taaattcatc agcagtcaaa aatcctgaat taataaggga
    15481 agcttcatta aaatttggag cacaatgtgt tgttttatcg atagatgcaa agaaaaatga
    15541 agagggttca tggagcgtat acgtaaaagg tggaagagaa aaaactaatc tggatgcaat
    15601 tgaatgggct gttaaaggtg tagaacttgg agcaggagaa atcgttgtaa atagtatgga
    15661 tgaagatgga atgaaaaatg gatatgatat agaattatta tcaaagataa cttctttagt
    15721 aaatgtacct gttatagcat ctggaggcgc tggaaaaaag gaagattttt atgaggcggt
    15781 taataaatcc aatgtagatg gaattttagc agcatctgtt tttcattttg gcgagataaa
    15841 aataaacgat ttaaagaaat atttaaaaga catgggtgta gaagtaagat tataagttaa
    15901 atactaaaag gagattagaa atatggataa taagtgtaac aatgtataca gtgatgaagt
    15961 agagaaattt ataagaagta taaagtttga tgataaaggg ttagtccctg ttgttgttca
    16021 agaggtagtt agcaaagatg tactgatgtt agcatatatg aataaagatg tgataaagaa
    16081 aaccttaaaa gataaagtag cttgctattt tagtagaagt agacaagaac tttgggttaa
    16141 aggtgagaca tctggtaata ctcaaaaagt agttaagatg tcttatgatt gtgatgtaga
    16201 tactatacta ctttttgttg aacaaactgg tgtagcttgt catacaggca attattcttg
    16261 tttttacaga gacttgtttg atgatagttc aaaaatggag cttgaagtac aaacaaatat
    16321 attgaaagaa ttatatgatt taatcaatga aagaaaaaat aatccagttg aaggttctta
    16381 tactaattat ctttttgaaa aaggaataga taagattctt aaaaaagtag gtgaagagag
    16441 tagtgaggta attatagcat caaaaaatac tgataaaagt gaacttattt acgaaattag
    16501 cgatttagta tatcatacat tggttttaat gatagaaaaa ggtgttgaaa ttgatgaaat
    16561 aaaaaaagaa ttacttaaaa gaagaaaata gaataagata gattaatggg taataagaaa
    16621 atataccact tttaataaaa agtggtatat tttttatttt atattttga
//
LOCUS       DAYAKB010000079        16649 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.079, whole genome shotgun sequence.
ACCESSION   DAYAKB010000079 DAYAKB010000000
VERSION     DAYAKB010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.079"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     misc_binding    442..704
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            780..3446
                     /locus_tag="ACGI3L_003005"
     CDS             780..3446
                     /locus_tag="ACGI3L_003005"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFG9198701.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            3871..4581
                     /gene="rgaR"
                     /locus_tag="ACGI3L_003006"
     CDS             3871..4581
                     /gene="rgaR"
                     /locus_tag="ACGI3L_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HFG9198702.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            5645..6658
                     /locus_tag="ACGI3L_003007"
     CDS             5645..6658
                     /locus_tag="ACGI3L_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFG9198703.1"
                     /translation="MNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYIFISDKF
                     DDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNIRLINLS
                     LSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFTLDGDDS
                     FWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEKPGITIS
                     DLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCLDIEENN
                     EKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLTELVERY
                     KNL"
     gene            6791..8089
                     /locus_tag="ACGI3L_003008"
     CDS             6791..8089
                     /locus_tag="ACGI3L_003008"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFG9198704.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(8203..8448)
                     /locus_tag="ACGI3L_003009"
     CDS             complement(8203..8448)
                     /locus_tag="ACGI3L_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HFG9198705.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            8596..9462
                     /locus_tag="ACGI3L_003010"
     CDS             8596..9462
                     /locus_tag="ACGI3L_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HFG9198706.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(9466..10002)
                     /locus_tag="ACGI3L_003011"
     CDS             complement(9466..10002)
                     /locus_tag="ACGI3L_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HFG9198707.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(10193..10396)
                     /locus_tag="ACGI3L_003012"
     CDS             complement(10193..10396)
                     /locus_tag="ACGI3L_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HFG9198708.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            10687..11451
                     /locus_tag="ACGI3L_003013"
     CDS             10687..11451
                     /locus_tag="ACGI3L_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9198709.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            11840..13153
                     /gene="prdC"
                     /locus_tag="ACGI3L_003014"
     CDS             11840..13153
                     /gene="prdC"
                     /locus_tag="ACGI3L_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HFG9198710.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      13558..13643
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            13942..14070
                     /locus_tag="ACGI3L_003015"
     CDS             13942..14070
                     /locus_tag="ACGI3L_003015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198711.1"
                     /translation="MDNQQVSFEKKKLQRLERNLVPTSVGKWGVPNLWLGNDIVCA"
     gene            14225..16399
                     /locus_tag="ACGI3L_003016"
     CDS             14225..16399
                     /locus_tag="ACGI3L_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HFG9198712.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQTPDVEKPSDGQ
                     MPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEED
                     VKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTL
                     TFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQE
                     NQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERL
                     KQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGK
                     PSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTGEVE
                     ISTQQKFKLKSVVKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQN
                     LLSYTIEKKNGQEVNFNIGLPTDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPP
                     MDDTIINPPVPPTEDAVLNPPVPPTEDAVLNPPVPPTEDTVLNPPVPSVSDTVEKTPE
                     LSRDDTIIKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
BASE COUNT         6749 a         1773 c         2876 g         5251 t
ORIGIN      
        1 atgaattagt agtattaatt catgagaaag agcaaagttt aaatgcttta aataatatta
       61 taagaatctt aaaagagaga ggatatacaa tattgccaat tacagaaaat ataacaccta
      121 aaaatttctg gcaagaaaac ttataataaa tttaaatata gtaaaagata aagtaaatta
      181 tttataaaat aaaacatata atataaaaaa tacgaataag aggtatactg taaggataat
      241 ataaaattaa tgagaaagca ttaaaattaa aataaaataa tcttgcaatt attgacatta
      301 taagacagaa taactgtaaa aacatatttt aaaatataac aactatataa aagagaatag
      361 acataattaa gaaaattcag aaaaaataaa ataaaaataa ttgacaaaga gaataatatt
      421 tgtatataat aatatgtaat attaaagact gagaagaaga ggagtaagta aatactacta
      481 aaagagagga aaattcactg gctgtaagat tttctaagta taagatttac tgaatgtagc
      541 tttggagttt ctaaactgaa ctataagtaa gtttagacgg ttagaaccgt taaattcttt
      601 gagagtcaaa gttgataaaa taacattaac caataattta atgatatgtt aatgtatttt
      661 aagctttgga attaaggtgg taacgcgagc ttttcgtcct ttttaaagag gatgaagagc
      721 tcttttttat ttctaaagat atttaaaaaa tttatttata aaatacagga ggcaggacaa
      781 tggaaaatac gaatttatca aaaacttata acccaaaaga ttttgaggct aggctatata
      841 aaaaatggat ggatgaaggg tattttaaat ctaaaccaaa tccagataaa aaaccattta
      901 caataatgat gccaccacca aatataacag ggcaattgca tatgggacac gctcttgacc
      961 atacacttca agatatatta atcagatgga aacgtatgga tggatatgaa gctttttggc
     1021 ttccaggaac tgaccatgct tctatagcaa cagaagttaa agttgttgaa agaataaaaa
     1081 aacaagaagg caagacaaag tatgaaatag gtagagaaga atttttaaag agagcctggg
     1141 aatggaaaga tgaatttgga ggaaaaatat ctaatcagct taaacaacta ggtgattctt
     1201 gtgattggga taaagaaaga tttactatgg atgaagggtg taatgaagca gttatagaat
     1261 tttttgtaag cctatatgaa aaaggtcaca tatacagagg aaatagaata ataaactggt
     1321 gcccagattg caaaactact ttatcagatg cagaagttga acatgaagaa cacgacggaa
     1381 acttttatca tataaagtac ccactaaaag atagtgaaga ctttttagaa atagctacaa
     1441 ctagacctga gacaatgata ggagatactg gtatagcagt aaatccagaa gatgatagat
     1501 ataaacattt aataggaaaa acagcaatac ttccattagt aggaagagaa cttccaatag
     1561 ttgcagatag ttatgttgat ttagagtttg gaactggtgc agttaagatg actccagcac
     1621 atgaccctaa tgattttgaa gtaggattaa gacataatct tgagcagtta aatactatga
     1681 atgaagatgg aactatgaat gaagtttgtg gaaaatatga aggtatggat agatttgagt
     1741 gtagaaaagc tatcgtagca gacttaaaag aacaaggtta cctaattaag ataaaagagc
     1801 ataatcataa tgtaggaact tgttatagat gccatacagt agttgagcct agattatcag
     1861 agcaatggtt tgttaagatg gaagaacttg caaaaccagc tatagatatt cttaaaaaag
     1921 gagaattaga atttgttcca gataaatttg ataaaactta tttacaatgg ctagaaaata
     1981 taagagattg gtgtatatca agacaattat ggtggggtca tcaaatacca gcttattatt
     2041 gtcaagagtg tggagaaata gtagttgcta gaaaaatgcc agataagtgt cctaaatgtg
     2101 gaagcactca ttttaaacaa gatgaagatg ccttagatac ttggttcagt tctgcattat
     2161 ggcctttctc tactctagga tggccaaata agactgaagc tttagattat tattatccaa
     2221 caagtgtact tgttacagga tacgatataa tattcttctg ggtagttaga atggcatttg
     2281 caggtatgtt ctgtatgaat gaaaagccat ttgaccatgt tttggttcat ggattagtaa
     2341 gagattctca aggtagaaaa atgagtaaat ctttaggaaa tggtatcgac ccattggaga
     2401 taatcgagca atatggagct gatgccctaa gatttacatt aacaactgga aattccccag
     2461 gaaatgatat gagattctat atggaaagag tagaatttgc tagaaacttt gcaaataagt
     2521 tgtggaatgc atcaagattt gtatttatga atattgatga agatataatt aaaaacatga
     2581 ctagagaaag tgttaaagag gacttaactc tagctgataa atggataata tcaagagcaa
     2641 ataatattgt aaaagaagca actaataaca tggataagtt tgatttagga atagcacttc
     2701 aaaagatata cgattttact tggtcagaat actgtgactg gtatattgaa atggttaaac
     2761 ctagattata tggagaagat gcaaatgcta aatctgcagc attatataca ttaacttatg
     2821 ttcttgaaaa aatattaaaa ttattacatc catacatgcc atttataaca gaggaaatat
     2881 atactcatct tcctactgtt gaaggatgta taatagtatc tgaatggcca aaatataatg
     2941 aagaagataa catggctgaa gaagaagata tgatgaactt attgatggaa ggtataagaa
     3001 gtataagaaa tgtgagagca gaaatgaatg taccaccttc taagaaagct aaattgataa
     3061 taatcccaag tgaagaaaaa atagaagcta ttgagcttgg taaagactat tttataactt
     3121 tagcatctgc ttcaaatgta gagatagcaa aagataaatc taatgttcca gaagatgcag
     3181 ttggagtagt tattgatggt gttgaaatat ttatacctct taatgaatta gttgattttg
     3241 aaaaagaaat tgagagatta tctaaagaaa agaaaaagtt agaaggcgaa ataaagagag
     3301 ttaatggaaa gcttgcaaat caaggtttct tagcaaaagc tcctgaaagt ttaattgaag
     3361 aagaaaaagc aaaaaaagaa aaatttgaag agatgattaa atctgttgag gaaagattaa
     3421 caaatttaga atctaaaata aaataaatat aagaattagt aaaaacatac aaaaagtata
     3481 tattctatac tttttgtatg tttttcttta tatatataca aatatgatgt tataattctt
     3541 tacagatgtg ttatattttt attttatgtt gtgaatatat gaattttatg tcttaaaatt
     3601 tataagcaat aaaaatttga tatattatga tgtttaatat agggtaataa atacatatta
     3661 tatttatttt actatatttt tttacataat atatctagaa aagtatagga atttatcgta
     3721 atttaagttt aaatattaaa gagaatttct ataagtagtt taatcgacaa tttaaattta
     3781 taaagaaatt taaatttgaa agctagtgag tacagtttgg aaattgaaat aaagtaaact
     3841 aaatgatatt ttagatttgg aggtgatatt atgttcaggg tagttatatg tgatgacgaa
     3901 aaaatacaaa gaagcatact aaaagagttt acagaaaaac ttttgtctga aagatgtcta
     3961 aattatcaaa tactggaatt ttcctgtgga gaagatttaa tatccaaata cccagaaaaa
     4021 attgatatta tatttttaga tatccaaatg aaagatatca atggaattga ggtggctaaa
     4081 aaaataagaa agtttgatga aaaagtagaa attatattta caacggcttt ttcagagtat
     4141 gccccccaag gttatgaggt tcgtgcttat agatatttag taaagcctat agagtatagt
     4201 aactttgcaa tgggtgtaaa tctttgtatt gataaccttc aaagaaagaa ggagcgttat
     4261 atagttttaa atagtaaaaa aggatttaat agaatactga tagattctat tttatatgtt
     4321 gaaactgtaa agagagattt agtcgtacat acaataggta gagattataa agctaatatg
     4381 agcatgaaac aagcagaaaa attactgtgt gaaaatggct tttttagatg tcatacaagt
     4441 tttattgtta atttaagaag aatagaagat cttagggata atatgattac tattaatgaa
     4501 caatttatac ctataagtaa gtatagactt aaagatttaa aagtagcatt aacaagcttg
     4561 ttatgtgata taatgtatta attttaaaaa ggtaattgaa aatatcgtaa aaaagattta
     4621 atgtcatcac agggctattg attgaaactg tcttaatata taaaatgtta tttatattaa
     4681 gacagtttta ttatgcaaaa tagcagttta tagattttta atatggttta acatgtatat
     4741 gtagaggttc cattatagta gcatgattat taattagtag cttgattatc aatatactat
     4801 tattgatttt tatatgcatt atatgtattt ttagaatatg attacctttt taaaataatg
     4861 attatttata aaactctata gatatttgtt tcatttagct acgcatactt taattaatta
     4921 tattaatatt taatggagta caatataaat attaaagcga catcttatag tttattgaaa
     4981 ctatagtaat gaattaataa atagtttaat tctatgaaaa gatttccttt tatgcaattt
     5041 atttattgaa atatgatata atatataaag gtgtaagtat tagttgttaa aataatattt
     5101 atattagttt ttatacatac ttggtataag tttttcatat attgattaaa attgatgttg
     5161 atttattatt tttagtattt tttcaccttt tgattcatac tttgtagaat ggtgtatttt
     5221 ctaaaactga ttataagaca agttcattca aattagcatt tttatatcat ataaataatt
     5281 gttcccccta aataagattt agatgtatag tattaaaatc aaaaagtata aaataaaatt
     5341 gatgcttaat catagataaa tattaataaa atatacaagg ggattgtcta ataaaaagat
     5401 aatctccttt tttacaaata attctaaatt gtgatataaa tctaaaaatt ttatcttaac
     5461 atttaaccat ttaatgataa taattgatat aataaatata aattaaatat atggtgtact
     5521 tattttatgt ttttagcaag aaatatagca tttaaaagat aaattgtgca acttaaatca
     5581 aagtttaaga tgaactatta acatagatat attaaaaact tttgtaatgg agaatatatg
     5641 tgatatgaat aataaagtta aggttgcagt attagataca ggaatagaca aagaacatga
     5701 ttacttaaaa gataatttag ttggaggaat tgcttttgaa tgtatgcatg attatatctt
     5761 tatatcagat aaatttgatg atgaagatgg tcatggaact gcttgtgcat caataataaa
     5821 gaaagagtat gaagatgtag agttatttgt aataaaaatt ttgagaaaag atggtattac
     5881 aaatataaaa gttcttgaag aagcattaag atacctttta gacactaaca taagattaat
     5941 taatttaagt ttatcagtca taggagtaga aagtgttaag ggcttatttg aagtttgcta
     6001 tgaattgttt agaaaaggaa aaataatagt atgttcactc gctaatgatt ttgacttaag
     6061 ttatccagct atgtttaaca atgttatagg tgtaagagga tttactttag atggagatga
     6121 ttcattttgg tacaacaaaa aatatgatgt tcaatgtgtt atggatagca attcatatat
     6181 aagttgtgat ataaataatt cctatagatt accaccaaaa tgtaatagtt atttatcagc
     6241 aaagcttact ggtaaaatag ctaagatatt atcagaaaaa ccaggcataa caatatctga
     6301 tttaaatgat aagcttgaat cattagcaac tagaaatcat tgggatagtt gtgattttga
     6361 tgagtgtagt agaattgtaa actttaaatt ggatttgtat gacaaagaaa atgctctttt
     6421 tatgaaagtt gctgacgttg ttagggattg cttagatatt gaagagaata atgaaaaact
     6481 ctttaagggt agccttttta ataaggagat aggcttggtt tatgataatt gttttaatct
     6541 gttgaaaaag ctagagcata gatttgacat aaagtttaat tatatggaca tctcaaaata
     6601 tgacttagtt tcaatatata cactgactga attagtggaa agatataaaa acttataaat
     6661 aaagatttgt agctaaattt aatgtagaag gtattaaatt atatgtattc tttgtcggta
     6721 gattaaaagt aaaaaatata ctataattag atagcataag agaaaatgcc aatacagggg
     6781 gagttagata atgaaatatg aagaagcatt agagtacata tcacaaacta ataaattcgg
     6841 tataagatta ggattagaaa atatcggaaa gttattagaa ttattaggaa atccacaaga
     6901 aactttgaat ataatacatg tagctggaac taatggaaaa ggttctgtgt gttcttttgt
     6961 ttctaatata ctaagagagt gtggatataa agttggttta tatacatctc catatttaga
     7021 aacttttact gagcgtataa gagtaaatgg acaaaacata ccacaggatg atgttgctag
     7081 aataattgag ttaataaaag aaaaaataga gattatggta aaagaaggct atgcatatcc
     7141 gacagaattt gaagtggtta ctgcaatggc attttattac tattcagaac aaaaggtaga
     7201 ctttgtggca ttagaagttg gtttaggtgg cagatatgat gctacaaata taataacaaa
     7261 atcacttgta agtgtgatag tatctataag tttggaccat acaggtatac ttggagatac
     7321 aatagaaaaa atagcgtacg aaaaggctgg aataataaag gaaaatggag tagtactagt
     7381 atatgaccag actgatgaag caaaggatgt tataaagtca gtttgtaaag agaaaaaagc
     7441 taaatatata gaagttgatt ttgatgatat aaacataaaa aaatcagata taaattctca
     7501 aatatacgat tgtactgtaa tgaaagaaac ttatagagac cttgaaataa aattgatagg
     7561 cgaacatcaa ataaacaatt ctatcttggc aattagtgta ataaaatatc taaaagacat
     7621 aaataaatta gcaaatataa atgaagaatc tataagaaaa ggacttataa atactaaatg
     7681 gccaggaaga atagaaaaga taaaggaaaa tccaattttt ataatagatg gtgcacataa
     7741 tgaagatgga gcaaaatctt tggcaaaagc acttgataag aattttaaag gtagaaaatt
     7801 aaccttatta ataggtatgt tagaagataa agatattgat agtgttttag agatattgtt
     7861 gtcacatttt aataaggtaa taacaacaac accaaataac ccaagggcca taaattcaga
     7921 tatattaaga gaaaaagtat taaaatatgt agatgatgta acatcaaagc atgagataga
     7981 ggatgcagta aattatacat tagaaacatc aagtgaggat gatattataa taagtgcagg
     8041 ttcattatat atgattggta cagtgagaac tttagtaaag aaattataat tttataaaat
     8101 aagtatacaa ataaaaatat aaaaaagagt tgtctaaaaa atggacaact ctttttatat
     8161 aaaataagtt tttaataatt ttactgatgt ttatataagt aattatatag attgacgtat
     8221 agctttagat aattggtctg ggcaagaagt accttttcca ccacagtcaa taccatttaa
     8281 tttatcagca acttcaagag cattttggcc aattattaag cttctaagtc ctgataaatt
     8341 accattacat cctcctataa actcagcatc aacaatcaca ttattttcat caacttcaaa
     8401 aatcatttct ctacaacata caccacttgg attaaatgtt actttcatta aaaagacctc
     8461 cattaaatat tatttctttt tttaacatta ataataatac caaatatatg cgtaataatg
     8521 caactataaa gcataataca agctaatgaa ataatatatt attgtagtat atgtattgta
     8581 gagaggaggg gttatatgaa aatctatatt tctaactact tatcaaagag tattagcata
     8641 gttgattatt ctacacttga actagaaaaa gaaatagtat tagaagataa tatatatcca
     8701 caccattttt gcatagaaaa agaaaaaaat ttaatataca tacctagttc aagtaatggg
     8761 atactctatg tcttagattt aagtaatgat aaaataattg atactgtctc tataggagga
     8821 agtcttagtc aagttgtact tagcgataat gaattgtttg tggcaaatga agattctaat
     8881 agtatatatg tactagataa aaacacatta aatccaatag gaattattgg agttgataat
     8941 atgccacatg gatttgactt tgatagagaa agcaaaaagt tatatgtacc gtgtataaac
     9001 tcgatagtat gtatagatac aattaataaa aatatacaaa agaaaataaa tatggacttt
     9061 agagcttggc atatagaact tgataaacaa aagaaagaaa tgtatatatc aacacttgat
     9121 ggaaagctta taataataga tgaagtaagc atggatataa aaaaggtatt atatgaattt
     9181 ttattaccag tagaaataag atttaattat agtggcaaaa aagtttatgt tgctgatttg
     9241 ggttataata atgtaagaat tttagattat acaacgagta gatacattgg aaatattgaa
     9301 ataaatggga ttccccaagg attagaaata tctaaagatg aaaagttact atttgtatca
     9361 gatacacaag aaaattcagt aaaagtttat gaaactgcaa ataacaaatt aataaaagaa
     9421 atcaaggtag gaaaagagcc tacaactata atttgtttgt aggctttaat gtatgtctct
     9481 tataagtaaa tcgataactt cggcatacat ataagatgca ttatttttcc agttattgca
     9541 aataagtttt gcttgtttct ctgatgaaac atttagattt aaatctatta agttagactg
     9601 attttctatg actctaaggt tgacaataaa ttcattatca ctttgtttta caaaactaga
     9661 ctttacttga gtatctgcta gtagattttc tttgttagaa tctatatact tgtctatttt
     9721 ttcagtaaca ctagtaggta ttcgattaaa gaagtattct agactttcta cgcctctttg
     9781 agtaagagca taatattctc tgtcagagtc tttatatgta gtcaaaaact tagattccat
     9841 aagctgagat aaaagctgtt gtaatgaaaa ataattcatc atctcagtct ctaatactac
     9901 ttgagttatt tgagaattag ttaaatccat tttaattttt tctaatatat ataaaattaa
     9961 aagtttgtga taggctaatt cttcagacga gttttcaaac ataaatatca tcctccgtca
    10021 aactatttct atatataata tattaaacta atttgtacaa aattaaaaga acaatttgta
    10081 ttgtattatt aatctttaat aattcatata aaaacaattt tataaataaa tatagaaaaa
    10141 cagggctgct aattagcagc cctgttgata cccaggtgtc aaaatttact atttattttc
    10201 cagccatttg tctttcagcc atttcaacta atttcttagt catatatcca ccaacatatc
    10261 cattttctct agctgttaag ttacctttgt ctatgttttc atagttagat aaacctattt
    10321 cgttagctat ttctaatttc atttggttta aagcagcttt tgcttctgga actactgttc
    10381 tgtttgaatt tgacatagta aatttcctcc tcaaataatt agtttatgat gtctaacaac
    10441 acttttattt atgtgatgtt aatactaatt tctccaaaat aaaaataata tatacagaaa
    10501 aataaaggta aaaatgtaaa aaatataaaa aaattaaata aatgagtatt ttagagagtt
    10561 taattaggtc aatataggtt ttattttttt agttattgtc ttataaatta aatattacag
    10621 tacttttttg agctgaaaaa aaataaattt taaatataga agaaattatt tcaaaggggg
    10681 aatagtatga aaagagaagt taaaaggact aaagctttga tatatagtgt tttatttttt
    10741 tcattattat tagtgttaat atttgttttt gtttatggaa taaaatacat atgttctaaa
    10801 tctgacaatt caaaaatgcc tatatataaa gttgatacaa atgagaaaaa aatagctttg
    10861 agttttgatg tagcatgggg aactgataat atggatgata ttttaaaaat tttagataaa
    10921 cataatgtaa aagctacctt ctttttagtt ggtagttggg tggatgataa tgaagaaatt
    10981 gtaaaagcta tagatgaaaa aggacatgaa attggaaatc attcaaatac tcatgccaat
    11041 ttgaaggaaa tatcaaaaga agacataaca aaagagatag aaactacatc agaaaaaata
    11101 tataatataa caggaaaaag gactaattta tttagacctc cttttgggga cgtaaacaat
    11161 aaagctatgg acatttgtag tgatttaggt tataaagtaa ttaagtggga tgtagattct
    11221 atagactgga aggagcttgg accaaatcat gtaattgaaa aagtaataaa agaatctcaa
    11281 cctggttcaa tagttttatt ccatgctaat ataaatgatg tagataacta tttggatact
    11341 ataataagtc gactaaaaaa agatggatac agtctagtca aaatatctga tttgttgtat
    11401 aaagataatt atgtagttga ttccaatgga gtgcaaaaaa ctaagaatta ataagtaata
    11461 aatgtatatt ttaagtaaag ttgtgataaa ttatatagta tatgttagaa aagtgtcgat
    11521 aaaaagacgg tgtctatttt ttgacacttt ttatacatgt atgcaatatc aataattata
    11581 gattaaattg attaaaaaag tgtctaataa ttgacttttt tttgatgggt ttaaaaattt
    11641 agaagaatta atgaatgctg taagacagta tttccaaagg gtataagttt gtttaaaagt
    11701 tggcatagaa attgctttgt taataagcga tatgttctat agaaataaac aatatgttaa
    11761 gaccttataa tagaaaaata gcattaacat tatttgaaca gcttataaaa aaattaatat
    11821 acttaagggg gcgtactagt tgaacaaact atattctatt ttattaaaac aacacgttgg
    11881 tggtccagat aagccagtag taagtgttgg agatgtagta aaaaaaggaa ctctaatcgc
    11941 agaaccaact ggattagggg caaatattta tgccagtgtt agtggaaaaa taagtgaaat
    12001 aaatgaccaa gcgatagtaa ttgaagctga tgaagtacaa gaagatactt ttgaaccatt
    12061 aaaaggagaa ggtatacttg acttaattaa agaagctgga gtagtaggaa tgggtggagc
    12121 aggattccct actcatgtaa aattaaacat agatttaaat ggtggaacaa tattagcaaa
    12181 tgcagctgaa tgtgaacctt tattagctca taatataaaa gaaatagaag aaagaccaga
    12241 aatagtttat caaggtataa aatatgctat ggaagttact aatgctggaa aaggtatgct
    12301 agcaataaaa agtaagcatc caaaagcaat agaagctttc aaaaaagtaa taaagccagg
    12361 agacaacata gaagttgcag aactagttga tatgtaccca atgggagaag agagagcaat
    12421 agtaagagac gttctaggaa aattacttga gccaactcaa ttaccttcag aggctaatgc
    12481 agtagtaata aacgtagaaa cactaactag aatagtagag gctgttgagc aaaaaagacc
    12541 agttatatct aaaaatataa ctgtagttgg tcaattaaac agtggaaaag aatctatagt
    12601 gtttgaagat gtgccaattg gaacaactgt cggagaatta attgaaagag ctggtggaat
    12661 aaaaggtgaa tatggtgaaa taatcctagg aggacctttc actggtaaag ctactacttt
    12721 agatgctcca ataactaaaa ctagtggtgg tataatagtt actatgccat ttgttaatga
    12781 aaagagaaaa atgggtcttt tagtttgtgc atgtggacct aatgaagaaa gaatgagaga
    12841 tatagcaact aaaatgggag ttactgatat agtatcagtt caaaaatgta aacaagctca
    12901 agaaattaaa ggtgcattaa aatgtgaaaa tccaggacac tgtccaggac aagctcaaaa
    12961 atgtattgaa tttaagaaag ctggagcaga agttatatta ataggaaact gtactgactg
    13021 tagtaacaca gtaatgggtt ctgcaccaaa attaaaatta ggtgtatatc atattactga
    13081 ccatgtaatg agaacagtta atcacccatt aataagaaga ataaaaggtg acgtaagatt
    13141 aaaaataaaa taatagataa atagaagtta gacatcttta gaagtaaaac ttaaaagtta
    13201 cttctaagga tgttttttaa tgtattttga gggcaatata tatattgtaa aataaatgga
    13261 aaaaatagac aaaatatgct agatattgta taatgataat aatagctatt acaattaata
    13321 ttggacaaaa ataatgatac tcaagtatgt ggtttgtatt aatatgcata ttatattaag
    13381 tcaactatcc gatagagtaa aaggtttttg tgatatttga agatactcta tagtatcttt
    13441 tttattataa aaactaattt ttgtctttta ttagataagt atctaggata ctaatttata
    13501 ttttattgag ttgttaaaaa agtgcactta aaaagttaaa aaagaaaaat taaaaaacct
    13561 atttatagaa actgtgaagt atatcttaaa cctgggcact taaaagatat atggagttag
    13621 tagtgcaacc tgctataaat ataaatagga gtaactttta attgtcaaaa atatataaaa
    13681 taaatacata aataagtaat taatagaaga tagatataaa tatatttttg aaatgctccc
    13741 tgcattcata acgagtgtag agtggcagat atctgcccaa aactccttta attgctggaa
    13801 gttcctaaag ctaactaaac cacaacataa tcatgaaata aggataagtg tgatagagtg
    13861 tgcatttaat aagcacttga ggttacgaaa gtagaaaaaa ttagttagat agcataaggt
    13921 taaatcctaa gtgccttgaa aatggataat cagcaggtaa gcttcgaaaa gaagaaactt
    13981 caacgactag agagaaatct cgtacctaca agtgtgggga aatggggagt acctaattta
    14041 tggttaggta atgatatagt ctgtgcttaa tagaaatatt aagaagttca taggagaact
    14101 ggttaggagt aacgacccta attgaacaca ctaaagatgt attattgaat aagattcata
    14161 taatatttaa taattttaat tatattaagt gaatacaata tatgttttta gtatcaggag
    14221 aattttgaaa acaaaaatta aaaaatcaag tataatcagt ttagtaattg cttttagtat
    14281 ggtgtttact gcatttacac caatagtatc ttatgctgac gaagtgacta gcaatgatac
    14341 aatacttaat ggagaagaac aatcaaatgg tcagacacca gatgtagaga aaccatcaga
    14401 cggtcaggta ccagatgggg agaaaccatc agacagtcaa gtaccagatg gggagaaacc
    14461 atcagacggt caggtaccag atggggagaa accatcagat ggtcagatac cagatgggga
    14521 gaaaccatca gatggtcaga taccagatgg agagaaacca tcagatggtc agataccaga
    14581 tggagagaaa ccatcagatg gtcagatacc agatggggag aaaccatcag atggtcagat
    14641 gccagatgga gagaagacat cagatagtca gacgccagat gtagagaaac catcagatgg
    14701 tcagatgcca gatggggaga aaccattaga tgagcaaact ccagaagaag aaaaaccatt
    14761 ggaagaagaa atagttatag aggaaatgag tttaaaacaa gatattgata aaattcttga
    14821 tatgacttta tctcaaataa ataaaatagt atataacttt tgggaagatg aagaagatgt
    14881 aaaggcagat gaacaatcag aaattaacca agtttttact tcagaagact catttattag
    14941 cttatggtat gacaaaaaag caaaagtaaa aaattcttgt ttactaaaag aaatagatgg
    15001 ttcagataga ccttatcatg atttaagatt tgatgatatt acaaagactt taacttttga
    15061 ctatgtaata aagggtcttg taggagcaag ctcaaaagac gacaaatatg taatagaagg
    15121 tgaagatgga gagcaaactg cattttgtta caataatcat ttaagaccac caagtagtaa
    15181 tggaaagagt ccatatttac cagcagaaga ttttaatggt caagaaaacc aaaatgaaga
    15241 agcagttaaa tctatactat atgcaggttc tgaatttgat ggatttggat ataagcaaca
    15301 atttaattta ggtggagaag aaaatgaatt gatgacttac tcagctactc aaagtgcaat
    15361 ttggattatt cttggacaaa tggatgaaca agaaagactt aagcagtatc aaggttctat
    15421 aaacctttgt gataaactta tagaaagagc aaaaactgaa gaggaaagag ctgagtatca
    15481 gaagaagaaa gaagtagcta taaatataaa agcttattta gaagcattgt taaaagcagg
    15541 tcgtgaagag ttaaagccaa atgatacagg aaaacctagt ttgagtaatg gtttaactaa
    15601 gattaacttt gaaaaaaatg aagatggtac ttatgaaaca gaagctgtag ccttagtagg
    15661 ttatagtggt gtagtaaagt taagactacc agatggagta actgcttatg atggagatgg
    15721 taatataata ggtacaggtg aagtagaaat ttcaacacaa cagaaattta aacttaagag
    15781 tgttgtaaaa ccagatgcca aagctaatat ttctgctgta tcttatgatt atatttttcc
    15841 aaaagctatt caatattata aggcagtgct tgatttagga caaaaagacc attcatcttc
    15901 attaccatct agtaagcaaa atttattaag ttatacaata gagaaaaaaa atggtcaaga
    15961 agttaacttt aatataggtc taccaacaga tgatgttgta aatccaccag tgccaccaac
    16021 agatgataca aatggacata agccaaaacc atcaccacca atagatgata cagtaataaa
    16081 tccaccagta ccaccaatgg atgatacaat aataaatcca ccagtaccac caacggagga
    16141 tgcagtgtta aatccaccag tgccaccaac ggaggatgca gtgctaaatc caccagtgcc
    16201 accaacagag gatacagtgt taaatccacc agtaccatca gtaagtgata cagtggaaaa
    16261 aactccagaa ctatcaagag atgatacaat aataaaatca ccaaaaacag gtgatgaaac
    16321 tcagctaatg tcatatgtat ttattagtgt cattgcaatt tgtggattag cgtatcaatg
    16381 taaaataaaa agaaattaat ctagattatt attaagttta aaataaaaag tctcaaattg
    16441 atttataagt cattttgggg cttttttatg taaatataat atgcaaatat agtttgttta
    16501 aaaatatata ttttaattat attcttaaat ttatgattgg atacaggcat tcattaattg
    16561 tttgatgaat agaaaaatgt tttgaaggtg aaaatagtat tgaaaaaata atatactaag
    16621 ggtataattc atttgatttc atttgtata
//
LOCUS       DAYAKB010000080        16334 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.080, whole genome shotgun sequence.
ACCESSION   DAYAKB010000080 DAYAKB010000000
VERSION     DAYAKB010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.080"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            402..1805
                     /locus_tag="ACGI3L_003017"
     CDS             402..1805
                     /locus_tag="ACGI3L_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9198713.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            complement(2282..3304)
                     /locus_tag="ACGI3L_003018"
     CDS             complement(2282..3304)
                     /locus_tag="ACGI3L_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9198714.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(3339..4937)
                     /locus_tag="ACGI3L_003019"
     CDS             complement(3339..4937)
                     /locus_tag="ACGI3L_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HFG9198715.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            complement(4979..6244)
                     /locus_tag="ACGI3L_003020"
     CDS             complement(4979..6244)
                     /locus_tag="ACGI3L_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9198716.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAE
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            complement(6386..6766)
                     /locus_tag="ACGI3L_003021"
     CDS             complement(6386..6766)
                     /locus_tag="ACGI3L_003021"
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HFG9198717.1"
                     /translation="MLEKNEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLFASIPN
                     GSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQG
                     KVKEEWITFDGMDVLKQIYMGVEE"
     gene            complement(6750..8108)
                     /locus_tag="ACGI3L_003022"
     CDS             complement(6750..8108)
                     /locus_tag="ACGI3L_003022"
                     /inference="COORDINATES: protein motif:HMM:NF019581.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9198718.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EK"
     gene            complement(8264..8920)
                     /locus_tag="ACGI3L_003023"
     CDS             complement(8264..8920)
                     /locus_tag="ACGI3L_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198719.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            complement(8946..9647)
                     /locus_tag="ACGI3L_003024"
     CDS             complement(8946..9647)
                     /locus_tag="ACGI3L_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HFG9198720.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     KKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            10455..10934
                     /locus_tag="ACGI3L_003025"
     CDS             10455..10934
                     /locus_tag="ACGI3L_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9198721.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            10931..11710
                     /locus_tag="ACGI3L_003026"
     CDS             10931..11710
                     /locus_tag="ACGI3L_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198722.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFIPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(11960..12460)
                     /locus_tag="ACGI3L_003027"
     CDS             complement(11960..12460)
                     /locus_tag="ACGI3L_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFG9198723.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(13072..13779)
                     /locus_tag="ACGI3L_003028"
     CDS             complement(13072..13779)
                     /locus_tag="ACGI3L_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFG9198724.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            complement(14582..15367)
                     /locus_tag="ACGI3L_003029"
     CDS             complement(14582..15367)
                     /locus_tag="ACGI3L_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFG9198725.1"
                     /translation="MNFENDFITPEFRKKYIGLVLDNAQNINKVYTTTFPDKEIIKQV
                     IDKDEKDILIFSHHAMGYIASDEGFPFHDIPLSYMEEMKNRRISFYVLHSPLDNYSDY
                     STSVSFAKAMGLEIVKPFCKYDDKIEVGVICKTSLKSIEEIKELIKKSVGHDVKLYDY
                     GDSVLKDGLVAIAAGGGSYPFVAREVAELGINLYITGFTKPLKHFEPVLEFHQIAKDN
                     LINVIGATHYSTEKFACMGMVDYFKNLGLESEFLQGKYYLEDL"
     gene            complement(15719..16189)
                     /locus_tag="ACGI3L_003030"
     CDS             complement(15719..16189)
                     /locus_tag="ACGI3L_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9198726.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
BASE COUNT         5798 a         2814 c         1847 g         5875 t
ORIGIN      
        1 aacaaatcct ataattatat tctaatatac tacctactac tttgcgctac aacaatttct
       61 ctatttatat gatttgtaaa atatagtaca acatttttta tcattttcat ttcaactaaa
      121 tttgtaatat tttattcaat acttaataaa tacttaatca atacatgctt tataatactt
      181 tactcaatat ataatcaata cataatttat aatttgtaat actttattca atacataagt
      241 agaaatctct atatacataa attcattttt tcatacatct tacaaattta tttttattta
      301 gataacatgt atattttttc catgaaaaat aaataataaa aaatagtaaa tatggaaaat
      361 ataaaattga ttaacaataa ttaattacct gaggtgtgaa tatgaaaatg ctaaacaact
      421 tttttaagaa aatcaacaat ccagctcctg tctttgcaca gacaaaaatg gaaagagata
      481 atcaaacaga tgattcactt tctacaaaac caaagactac atttagagac gttgctggat
      541 tagacgaagt aaaagaagaa ctatttgaaa tagtcgattt tatgaagtca ccacaaaaat
      601 atcaaaaaat gggtgcaaaa atacctaaag gagtattatt ttatggtcct ccaggaacag
      661 gtaaaaccct acttgcatct gctgtagctg gtgaaacaaa ctcatcattt ttcaatgtta
      721 ctggttcaga gttcgttgaa aaatatgtag gtgtgggagc aaaaagagtt agaactctat
      781 ttgaaaaagc tagaaaagaa gctccaagta taatatttat agacgaaata gatgctgtag
      841 gagcaaagag acatcttgaa agtaacaacg aaaaagacca aacactaaac caacttttag
      901 ttgaaatgga tggatttaat aaagattcca atgtattaat aataggtgct accaatagac
      961 ttgacttatt agatgaagct ttacttagac caggaagatt tgacagacac attcatatag
     1021 gtgcaccaaa ctatcacact agatttgaaa ttctaaaggt acatacagat gacaaaccta
     1081 tagacaaatc tgtaaatcta gaacttttag ctaaaaaaac tcatggtttc aatggggctc
     1141 atctttcaaa tatagcaaat gaagcagcta tatttgcagt tagagatgac agtgagtgta
     1201 ttacatcaga acattttgac aaggcacttg aaagagttat tgcagggcta gaatctaaaa
     1261 actctgcatt ggttgaaaaa gagaaaaaaa tagtagcata tcatgaagct ggacatgctc
     1321 ttgtaagtga tatagtagga atttgtccta tacaaaaaat atctatagtt cctagaggac
     1381 aagcattagg ttatgttctt caattacctg atgaagatag atatatttat actaaggatg
     1441 agttgattgg aaaaataaaa atattacttg ctggaaaggc ttcagaagaa ttaatattta
     1501 atcataaatc tactggtgca aaggacgact taaagaaagt cactgaaata gctaaccaaa
     1561 tggtttgtga atatggtatg agtaacttag gatttatgac tattgatgga aatgataaga
     1621 ctttcttatg tgataaggtt caaaaggaag caaatcgtat agttgaaatt tgttataaag
     1681 agactttaga gatgttaaag gataatcttg aagatttaca ttctgtttct aaattcttat
     1741 ttgaaaaaga aactatgact catgaagagt taaaagattt gataggaaaa gaagctgtaa
     1801 actaatatag ttttaaaaat ttgaggctgt ctcaaaatag agataagcct ctttttattg
     1861 ttaaagttat aaaaatacat ttgattttat acaaaaaagt gcctcataaa ctaaaaattt
     1921 cattttgaga cacttacata ttttaattac atattttaat tttgtctatt tacagaatat
     1981 tatatctaca taaaactaaa ctgctgtaaa cttaactacc tccagtaatg tttgaagtgg
     2041 tataaaagct agtagcctag tttctacact tataatttat attttacata actaaattta
     2101 gtagattttt atactcacaa tttagaacga ttgaaaactt aaaaatttct tatcagatat
     2161 ctacaactta attaggtatc tatcacttga ttaaatatct atcacttaat taggtatcta
     2221 tcacttgatt aaatatctgc catttaatta aatatctacc acttaattaa atatctacca
     2281 cttaaagtgt agaacctctt tcaatcaatt caggttttaa catttcaacg actgactctg
     2341 gattttcttc atttaataag gacttaagta tgttaattgt tttttcaatc aacaaatcta
     2401 gtggctgtct aatcgtcgtt aaattataac tcttccatga agccatttga atatcatcat
     2461 atcctatcac tgataaatcc tctggcaccc tcaacttgta ctcaaacctt gcagcatcca
     2521 ttacaccaat agctatcaag tcacttgtgc aaaaaattgc tgttggagga tttgataatg
     2581 ctaacattct cttacctgct tcatatccag aatcataatc atagtttgca gattcttctt
     2641 taaggttatg aatcccactt tgtcttaact tagagtaaaa tccaattttc ttttccattt
     2701 cttcacttgt ttctctcgta aattgaatat atcctatatt cttatgacct ttcttaagca
     2761 gatattcagc agccattccc ccaccttcaa ttgggtctac atagactgta cttattttta
     2821 taccaggtat aaaacgatta aaaagaatca caggaatatt gttttcttca caagtctcag
     2881 ccatcacctt attcatggcc gaagctgtaa taatcacagc ttctacttga aactgaatta
     2941 cttttgaaat tatactatct atactttgtt gtctaggaac tttaaaaacg agacactgtt
     3001 tacctatctc ttgaattttt tctacaaata aattgataat tctattgtaa aatggaccta
     3061 gactatcacc aactatcaat cctataacat tagtttttcc actaatcatt ccccgtgcta
     3121 ccaaattagg aacatatcct atttcatttg ctacacgaaa aattctttct cttacttcag
     3181 gttttacgcc ctttccattt gcactaccaa atgctcttga aacagatgat tgagatactc
     3241 ctgccaatct tgcaacatct tttgaggtag ccgatttatt ataatgaact ttcttttgat
     3301 tcatttagta tttctcctta aatatctagt atttcttctt aaaattgtat caaaaataat
     3361 ataatatatt ggataataaa aaaagctaat acaattaatt cttgtttacc taaagaaaat
     3421 ggcactatag atactccatc tactttatcc attccttgag aaataaggtg atttctcata
     3481 ccaaatgcag tgtatttttt aatatcatct gcattatgat ttttctttaa aatgacacta
     3541 aaaatatatc caaatatcaa tgttattgta gcacctattg ctggattcca caaccaactc
     3601 acattatatt tattagaaat aaaaaatcct aaaactaacc ctacaataaa accaatagat
     3661 actcctttat cattagcttt atatgtaaac attgctagta caaatgcacc tgtagctggt
     3721 ccagcaaagt atgagatata gttaccaaca aggtcaagaa ttgatttgat gcttcctcca
     3781 aatcccataa taataaaacc tgtcataaca actcctataa ctacagttat aatcattgta
     3841 acttttaatg atgattcttt gttatctttt ttgaaataaa actcataaat atccttcgta
     3901 aaaacagttg tcatactgtt taatatagag tcgatactag acattgctgc tgcaaacaca
     3961 cctgcaataa taattccaat ggctcctact ggaagttcat ttaaaataaa agtaatcatt
     4021 atttcatttg aagtttcaaa tgtccttccc ccataaaaaa caaataaaat tactcctacc
     4081 aatagcataa agtagtaaac taaattcata acaaatgcac taactacaaa agaatttttt
     4141 gcacatttta aagatttaga tgttaaaact ctttgtactt gagattggtc aaaacaaaag
     4201 tatcttatcc acattacagt tccaccaatt aaagtagccc aaaaagtatt tgtcactgaa
     4261 atatccctac tgaaatcaaa tgtatttaat tttccactct gttgtgcaat ttgtaatgta
     4321 tcaaagaaac ttagattcat tccttttaag gctacaataa ttactataaa tacagcactt
     4381 attactacta tcatttgaat actatcagtc catataactg ccttaatccc acctaataga
     4441 gtgtatataa ttgatacaag tacaactatt gggactaaag cataaagtga ccagccagta
     4501 atcatttgaa taataagcac tggaatatat accatagaac tagcttgaat caatgaatta
     4561 ataaaaaatt gaataatagt taatcctctt gaataatttc ctaaacgaag tcccatatat
     4621 tcatatatag aggttatttt taatttatag ataactgggg tggtaatgct cagtgcaaaa
     4681 aatattgcta aaggtactgt aatattaacc attactggat acattccatc tacatatgcc
     4741 catccaggac cacctataaa gccatttgca ctaatcatag tagctgcaac tgataaagca
     4801 attggaatcc atggcattga cctacctgcc aagaaataat cttcttgatt tttattatct
     4861 tttcctgaat aataaccaat aactaacatt aatagcaaat atcctattat aatacataca
     4921 tcaattgatg aaatcataag ccaccccttt ctaagtaaca aaataaattc ctagtatttt
     4981 attttttatt atttaacgtc tctggtaaga ataaccatac aatagcacct gctacaaaga
     5041 ctgcgattga tatgtaaaag atagtcatca tacctaaagt accagaagct gtaccagcta
     5101 tagcaggtat tgcaaacgta gatataatcc ttcctccatt aaatgacata ccagatgaca
     5161 acgaacgata tttacttggg aacaactctg tgtagtatgc tccccatgct ccagaatatc
     5221 caacagcaac acctagtaat actgatatca tatagaatgt tgttgtatta tctccaccta
     5281 attttgtata tataaaaaca aatactgctg ctaatgccat acctataaaa ggtatttttc
     5341 ttccaaattt atctgcaatt gaaccccaga ataaatatcc tactaattga ccaattcctt
     5401 gtaaactata tatagactca gccactgctg ctgacattcc tattcctgtc actaggtatg
     5461 tagttgcatt atttgaaaat gctgaatatg ctgtaaaatt tgcacctgat aaaagaatcg
     5521 ttcccaatcc aatccataag tattttccct tatacatact tatatagcta atcttttcac
     5581 cagtttcttt tcccttttta actaattcct ttgtatactc caaatcatct ggcacaaaga
     5641 agattgctaa gatagctcca actataggtg gtataatcgc agtatacatc aatatttgcc
     5701 aatttgcatc acctaaaacg ccatatactt tcccaccaaa aatcattgct aatgaaaata
     5761 aagcagttaa tatagcagct aacttaccac gatatttact tggaaacata tctgcaacta
     5821 aaggcatagc tgttccaaat acgcctccca acactactcc tgtacacaaa cgtgctattt
     5881 tccataacat aatatttgta ggagataaca ttggtataaa tgttgtcaat ccaatcagta
     5941 aagcaacgct aattaaagtc ctcttcttcc caatttttgt agaaatcacc ccaaaaataa
     6001 atgtacctgg aattgtacca aaagacataa ctgcaaatat ttcttctgtt tgttttaatg
     6061 aaaaaccaaa tcccccatct gctaaagcat aaatcattgt tggtttaata aaagtaccca
     6121 ccataaaatt gtagcaataa aaaaagtata ttaaagcaat tgaaaaaaat gcaattcctc
     6181 tttttaggtt tgaatagtct tttcctaata tgatatcatt ttctatttca accgttgttt
     6241 tcatattttt ataattcccc cttttaaatt tagtcataat tttgctaaaa gtttaaacat
     6301 ctatttttca tatacattcc ccacttaaat tttataaagc aatacttccc tatatatttc
     6361 aaaactattt atactctaaa cagctttatt cttctactcc catataaatt tgttttaata
     6421 catccatacc atcaaaagtt atccactcct cctttacttt accttgtagt atatgataat
     6481 gattgattcc cattacttct atatgctttc cagaaggctg tccaaaaaat cctatacctt
     6541 catttattcc acgtaatctc catcttacag atacatcata accttcattt ttttctcttt
     6601 gattacaagt tactctttcc acttcataac ttccatttgg aattgatgca aataaactta
     6661 caatcattcc ttgaatctca tcatagccat ttaaatcttt atcacatata aaatgtacta
     6721 ctgcattatc atgatagtat tttttaactt catttttctc taacatagta agagaaaatt
     6781 cgtccaaaag taccaaatgc acgaggatga ggctttccaa gagaaagtaa accttctgta
     6841 gaaaggtcca tactatcaga acctatacat gactttggat ggcaaacaac cttatctgta
     6901 tcctcttgac cttgtgtatg aacaactact tgaattttac ttttttcttc aatcaaaagc
     6961 ctaaagaacg tatcaaatgg attttcacca ttgattttgg ctacctccat taaagtttta
     7021 ccctctacat atttatttgc ttcagtcatt acagaggcta gtacaacacc gttccaccca
     7081 cctgctaatt ggtagaaaca ttgccatcca ggaatccctt cctccaactc ttttataatt
     7141 ctgtctctat tttcttgtac ttctaatcgt tttaccatat tttctacacc gccttcaaaa
     7201 gcccaaggag gtaaaagtgc acccaaagat gtcattccag ctgtatatgg gtaacaatca
     7261 aaagttactt ccaaaccatc tgcctcagct tcatctagct ttttaaatac ctcatcaata
     7321 gttccaaaat tcttatgacc cataactttt aaatgagaaa tatgtagagg aactcctgca
     7381 gtcttagcta tataaattgc ttcatcaaga gcttccattt cttcatcacc ttcatctcta
     7441 atatgagata tatagtatcc attgtatggt atcaattcct tacataattc agccatttct
     7501 tctttctttg tgtatgctcc tggtaaataa actaatcctg atgaaagagc tacacatcca
     7561 gcttccatag cttttctaac ttccaacttc atatttttaa gttgctctaa agtagctggt
     7621 tcctttgaaa atcccatttc attgatacgt acaggtcctt gtgctacata agctacaaca
     7681 ttgactgctg gagaattttc agttaagtaa tcaaagtatt cttgcattgt attccaatga
     7741 agctctaatt ttgttggaat tgtaccaatt atcctagttc caagataatc aattaactct
     7801 tgcttcttct cttctcttat cggagcaact cctataccac agtttgcaat aacatctgtt
     7861 gttacacctg tatggatacg gcttcttgtg tatttatcat acacaagaga taaatcagaa
     7921 tgagtatgga aatctataaa accaggtgat acaaattttc cagttgcgtc tatagtctct
     7981 ttagcctctt tttgacttaa atctccaata gccatgattt tgtctcctac aatccctaca
     8041 tcacttttat atcttgaatt tcctgtacca tcaacgatta ttccattgac aattttaaca
     8101 tcaaacatgc tttttctcct ttcaagactt atttatattc atatttctta ataaacaatc
     8161 ctattctttt ttctcaacaa ataattctag tctttctcct taataaacaa tcctattctt
     8221 tttctcaaca aataattcta gtctttctcc ttaataagca atcctattct tttgttttat
     8281 tgttatcaat tacaaagaag acccttgtga taagtatccc acctaacaca ataaacaatg
     8341 ttaataatcc acctggtata ccaatttttt caccaaagta cataattgct aacgctacag
     8401 caatcgtaca tccaccagct cgaatatcct tacgtgcaat atcaacataa attgctccaa
     8461 ataatgctgg aagtatataa ttaaatgaat tagtaacaaa ttcaggtaac aaaggaatta
     8521 ctttatagcc tacaatggta aaaatggtaa tcatagaagc tgatacaaag attgaacaac
     8581 atgtaccaat tgttccaaca acttcaccct catgagttcc tgcttctaca cctgcaattt
     8641 tctgtgccat tgatgctgca ggcatacgta tatctccaac agaacctgca agccaaccta
     8701 tataagaacc tggagctcct agtgtaggat aataagctat aggttgaaca atccaactaa
     8761 ccccataagt cgcagcgact aacccccaaa tttgaaatat aacagaaagc attggcatct
     8821 gaccaaagcg aatacctaca tagatagcgg gaataaagtt tgcaataatt gcaagaccta
     8881 tagaaattct ccctattttt atcatctttt tatcatacat aattatcacc tcttatccgt
     8941 tttaatcacg ataatataat ctgtgtacca aacataccaa ttaacatggc aatacctaag
     9001 gataattctt gtaatcgttg attcttttta aataaagttg tcaatactag cataactata
     9061 gctgaaataa ttgctggtgt aagttttggt atttcaaatg tttttatttg atttgaaaga
     9121 aggtaagcaa ataatccaac tgtagcacct gcaagtagtt ttttaaccca agtaggatta
     9181 tacttcatgt tcatcttttc aacaattcca cgcattctat gacccaaaat aaatacaaca
     9241 aatagccaac ctaagttatt taaagccatc ccccatagtg catacgaaaa agcttctgct
     9301 ccaaatgcag cactacctac ttctacccca gataaattgg atgtaagaga tattactcca
     9361 agctctgttc tagctgctcc gacatcacag agcctcatcc aagtcgtagg agcgccaatc
     9421 acagctacca gtgataataa tgtaataaca ggagatagag aaggtccaat ggctgtaaca
     9481 ctagctgagc gaattgctgc tttaattcct ttcttttcaa taccaagatt tgaagcctct
     9541 tttagtgcct ctttcataaa tacgattgct tgaacaactg aaataattac taaaaaacta
     9601 gaaacaatcc aaagacctgg gctattaatc atttcttgaa acttcatact ttattcctcc
     9661 ttaaaataaa tttttcagca ttttattgtg agctttcttt ctgtaatctt gttatgtttt
     9721 tatattgttt taatttattt tatctaagat atagtatctt taataggaga ttatctgtct
     9781 taaagtctca ctaaaaacat taatacttaa atattttatt cataattagt aaatatcaga
     9841 aaattcacat attatttttt taacctgtaa ttaacttata aggtctttta ttattttgac
     9901 atttcaatat aaaaatttta atcaaaaaac tttattattt taaaaaaaat tattattttt
     9961 ataatttata ttttttaagt ttatttatgt tcatctctat ctaaaataat gacatttcta
    10021 actcttaatt ctcatttaag tttcattgtt ttttcttaaa agcctacttt tagtcaagat
    10081 actgttatct ttactcatta tttaaagaac ttattttaaa tctgtacatg aagtaaataa
    10141 tccaaaagca ttgttattct aactactcaa cattaaatac ttactatttt ctaattactc
    10201 aatataaaga cttactataa aactaaatac ataaatggct tctaaagttt aatatatcta
    10261 catggcttta tatatgacag gaaaaatact agaaaaaata tattatagaa tacttgtata
    10321 taataggcaa aactttcaaa cttaaattta tcaaataatc ataaaaaaag tgaaccatct
    10381 atagtaaaat tttatctaat aagtgaaagg caaaaaagta gcgctacgat ttgcatagaa
    10441 gggaaggaac ttagttggat aaaactacat ttacaaacaa tatacttgaa tcagaacaga
    10501 ctttgtatcg agtatctaag tctattctag gaaatgacca agactgtgaa gatgccgtca
    10561 acaatgctat tttaaaagca tatgaaaagt tggattctct taaggaagaa caatacttta
    10621 aaacatggct gattagaata gtcataaatg aatgtaattc attaagacgc aaacgattaa
    10681 aatctctatc atttgaagat gtcttcaaaa acaaaaaaat tgatgaaaaa gatgactata
    10741 gcgatttgta tactgctatt caaagtctac ctaaaaaaat taaaattcca atagtccttt
    10801 actatattga aggttattca gtagatgaag ttaaggaaat attagatata cctcaaggaa
    10861 ctgtaaaaag tagattatca agaggaagaa gattattaaa aactaaatta gaaaacacag
    10921 aggtaatcat atgaataaaa atatattaaa taattcgttt ccagaagttc cagaaagttt
    10981 tcataatagt ttaagcaaaa cactaaatag tttaccagaa agagaggaaa attataaaat
    11041 gattaataat aaaacacaca aattaccatt tagaaaaggc ttagttgcaa ctttagccat
    11101 tactttgata ttgagcacaa cagcccttgc agtaggacat atatatagtt tagttggaaa
    11161 atcaagtact aaggctacct atacatctat cccaactaca gaacaagtaa aaaaagactt
    11221 taactttacc cctaatatag tttctgaatt tagtaatgga tataaattta aaggagcata
    11281 tactgtaaat aaaaaagcat ttgacaaaga aaataatgtt ttaggaaaat caaaagcact
    11341 tagttttgaa tataaaaatg gcaatgatga aatatctctt gacacagcaa ataatgtact
    11401 tgggaagagt tctgacaatc taaaagttgt agatacttac aaagatatta atatttctta
    11461 tgaagcattc gcacaaaagt ttataccaga aggttataaa atgacagaac aggataaaat
    11521 tgatgaaaaa tcaggcaaat acacatttag tgtggggcca aataatgaat cagacaaagt
    11581 tgaagttaat gaatttaagt ttttgacatg gaaacaagat ggagtttact attcttttac
    11641 agttcaagac tcaaatttat ctatgaatga cttagttaaa atggctcatg aagtaataga
    11701 tgcaaaataa acataagtaa taataagttg tttatgagtt tattatttat gactttaatt
    11761 tttttattag taaacatggt tgtatcttcc atctttatat tttctttaaa tttaatatat
    11821 aaaattttag atatttagct accttcaaaa gaagcattat taaaaagccc ttaaaaatat
    11881 ttcttttata tggaatttta agggctttaa ctttatttta tacaagtgta tatggaattt
    11941 taaagacttt aactttattt tatataagtg taagctccat ttgaattact tcttctttta
    12001 caggtctatc attccatgta aaaccactag atattgtatt tacctctaca aaccctaaag
    12061 atttataaac atgaatagct ctactattac ttttaaatac atcaagctca attttttcat
    12121 acccatattc ttttgataaa tcaataattt gttttaaaag actacttccg ataccttttt
    12181 ccctatactc tttaagaata cccatgccta aataaccaac tttttcagtt ttaggtaaaa
    12241 cgtcacacca accaatacag ttatctgatt ctaaatcaat tataaacagt tgtggtaagt
    12301 ttttatttat aatatttttt ataaattcaa ctgtttcttc aaaaggaaag gcttcatcca
    12361 tagctagata tttcctctct tttgctattt tatcaaaagt ttgccaatac gaataaatat
    12421 acttttcttc tgcctttata aattttatgc cttctatcaa cttaacattt ccccttttta
    12481 atttttgatt gtagttaact tattttatat gattctagtt tataatgcta tataaattac
    12541 tatatattag cttaaaatat ctttgtatat ttctataaaa ttaaaaccaa tatatctatc
    12601 tcttgcatct ctattaaaat aatttttaat agtataataa atatagttct ttaatctttt
    12661 gggtatatat acttaatcat tttgaaattt gatttaaagt ataataaaat atataaaaaa
    12721 atatataaaa tggtactata aaatttttaa tcttcatcaa tacctttttt gctttcattg
    12781 ttaaaactat tttttctatt agtttatttc ttataaaaca aacatttagt attaaaatat
    12841 atatcacaca atagtatttg caatttaact ttaaaaaaat aaaaataccc aactgaccta
    12901 agcaactcga ttgggtataa ataatctaaa aaatcatttt tgtataaact ctttatttaa
    12961 cttacatttt tatttacctt ctactttaat tcaacttata tttctatgct tcttatactc
    13021 tcattcaact tatatttcta cttatcttat acttttataa attcatcaca attatttagt
    13081 tctcgctatc aaagaaattg tattaaaata ctttccattc tctacttcca tcattttttt
    13141 gtcatttata gcatatgaat tatcacaatt tatccaatcc ttccaagctt catcatgaca
    13201 atttaaagct tcacatttct ctacaatcac agactccgat tcagaccaaa gtttattcca
    13261 ccatgtaatt gaatggaagt tcatattatc ttgccaaaat ggaatgagtt catctggtat
    13321 acaatccacg aaatcttctt ttaatccagg cattgccata gcaagtattc ccccctcttt
    13381 tacaagaggt gatatatgat tgtctaaaaa tccttctttg tttccaaaat agtgataaga
    13441 atcgatactt atcaccgcat caaagaaacc ttctgcataa ggtagttcat gtgcctctgc
    13501 ctgtattgga aatattttat catccaattt aaactcttta aatcttttat agttttcagt
    13561 tggttctatc cataaatctg ttgcaaatac agtagcatca aattcctttg ctaaaaatat
    13621 cgaagatata cccttaccac aacctaagtc taaaatacgc attccctttt ctagttttat
    13681 cttacttgtt aattcttcca atatttttat acaattaggt cccatcatat ttttcatgag
    13741 aaagtcctta tcgtatttat tactttttgt aaatatcatt ctatctttcc tttccctatc
    13801 agttattatt tattaaattt tatacgtttg attttttatt ttttatctgc ttcttatatt
    13861 gagcaatctc ttttttattc attctttaac agacaatttt aatgtgtaat tttatccact
    13921 ctgtgatagt aactttaatg aataatctta tctactgtga tagttatttt agtgagtaat
    13981 tttatctact ccacagcaat cgctttaatg agtaatctta tccactctat gatagttatt
    14041 ttagtgagta attttatcta ctccacagta atcgctttaa cgagtaatct tatctactct
    14101 ataatagtca ctttaatgag taatcataat ttttatatca ttttagatac ttactctaat
    14161 aagaattcat tttctaatac ttaataagtt ttaattactt ccactttaac ctatatacta
    14221 attaacttat ttaatttagt gcatatttga cactttacct tttattatac catttattat
    14281 cataaatata ataattctat ttttttaaaa taaatattta taataatcta aaataaatat
    14341 ttataaattc taatcaaccg taaataataa tctaaaatac atcaaaaaat aaactaaaaa
    14401 atatcgaaaa ataatttaaa agacatcaaa actaaatctt ctaatcagca attaaaagtc
    14461 tattttctta gtttaaaaaa taaagataga ttttttcaaa acactggata aataggtaaa
    14521 aaaataaaca gttagtaaaa taaattttta ctaactgttt atttttattg tttaatatgt
    14581 cctataaatc ctctaagtaa tattttcctt gcaaaaattc tgattctaaa cctagatttt
    14641 taaaataatc aaccatgccc atacacgcaa atttttctgt agaataatga gtagcaccta
    14701 taacattaat taaattatct tttgctattt gatggaactc taatactggt tcaaaatgtt
    14761 ttaaaggctt agtaaaccca gtaatatata gatttatacc aagttcagca acttctcttg
    14821 ctacaaatgg ataacttcct ccccctgctg caatagcaac taaaccatct tttaatacag
    14881 aatctccata atcatacaat ttcacatcat gaccaacaga ttttttaatt aattccttaa
    14941 tctcttctat tgattttagt gatgttttac atataactcc tacctcaatt ttatcgtcat
    15001 atttacaaaa tggtttgact atttctaaac ccatagcttt tgcaaaacta acagaagttg
    15061 aatagtcact atagttgtct agtggagaat gtaatacata aaaagaaatt ctacgatttt
    15121 tcatctcttc catataagat agtggtatgt cgtgaaatgg aaaaccttca tctgatgcta
    15181 tgtatcccat tgcatgatgt gaaaaaatta aaatatcttt ttcatcttta tctataactt
    15241 gcttaattat ttctttatca ggaaaagtag ttgtgtatac tttattaata ttttgagcat
    15301 tatctaatac taatcctatg tatttttttc taaattctgg agtaataaaa tcattttcaa
    15361 aattcataaa actccaatca tcattaatat ttttaatatt aaattctaaa tctaattttt
    15421 tataaagttc aattgcctta ataataacca ctcctttata ataatattga attactacat
    15481 attaatatag aaatttccga taataaactt tatacgttta agtattccta cttcaaatta
    15541 aaaatattat aaatattcaa atttattaat atattttaat attatattta ttttttcttt
    15601 attaatattt tctttatttt aatttaattt atgacatttg tcaaatacta gtcctatata
    15661 ttatcttgaa ttagttctat tacaattaat ttctactaaa taattataat ttaaacaatc
    15721 attccttact attttcacac tgctttacaa atttaattgg atgttgaatt attttagaag
    15781 tttcttctac agagtatccc tcagataaat atcttctagc tataacttcc atagactctc
    15841 ctatctcaat aatatgctta tccgggtcat aaatacgcac tactctttgt tgccattcat
    15901 gttttagtgg cttatggaca aactctacat ctttataata attgagtttt tcaataaatt
    15961 cgtcaaaatc atcaacctca aaataaagtt ccatattatt tgatttttgt ataattgtat
    16021 ctggattaat ccctgtaagc catgcgaagt cttcttgtat agcaaatcct cctttaaatg
    16081 ttacattttt gcctaagtcc aattcaattt cttgctcaaa taattcttta taaaattttt
    16141 ttgatacttc aatatccttc actgctaata atgaaacctg atatttcata aattttcctc
    16201 ctaatttttt atttctattt tttcagtatc ttctattaac atttttttct ctatctcttc
    16261 agtacctttt attaatcctt tatttttact tttttagcat cttctattaa cacttttgtt
    16321 tctacctatt cagt
//
LOCUS       DAYAKB010000081        16227 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.081, whole genome shotgun sequence.
ACCESSION   DAYAKB010000081 DAYAKB010000000
VERSION     DAYAKB010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16227
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.081"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            440..3343
                     /locus_tag="ACGI3L_003031"
     CDS             440..3343
                     /locus_tag="ACGI3L_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198727.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEEDEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDESLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            3376..3822
                     /locus_tag="ACGI3L_003032"
     CDS             3376..3822
                     /locus_tag="ACGI3L_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9198728.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGDMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            3945..4247
                     /locus_tag="ACGI3L_003033"
     CDS             3945..4247
                     /locus_tag="ACGI3L_003033"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9198729.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            4428..5834
                     /locus_tag="ACGI3L_003034"
     CDS             4428..5834
                     /locus_tag="ACGI3L_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFG9198730.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPVITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            6178..7236
                     /locus_tag="ACGI3L_003035"
     CDS             6178..7236
                     /locus_tag="ACGI3L_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9198731.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVNIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMEKGDIIFKPMISDKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            7335..8021
                     /gene="araD"
                     /locus_tag="ACGI3L_003036"
     CDS             7335..8021
                     /gene="araD"
                     /locus_tag="ACGI3L_003036"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFG9198732.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            8039..8686
                     /locus_tag="ACGI3L_003037"
     CDS             8039..8686
                     /locus_tag="ACGI3L_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFG9198733.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(8859..10226)
                     /locus_tag="ACGI3L_003038"
     CDS             complement(8859..10226)
                     /locus_tag="ACGI3L_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFG9198734.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(10416..10504)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10932..13052
                     /locus_tag="ACGI3L_003039"
     CDS             10932..13052
                     /locus_tag="ACGI3L_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFG9198735.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRLFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            13156..14409
                     /locus_tag="ACGI3L_003040"
     CDS             13156..14409
                     /locus_tag="ACGI3L_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HFG9198736.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVIAMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(14563..15624)
                     /gene="ytvI"
                     /locus_tag="ACGI3L_003041"
     CDS             complement(14563..15624)
                     /gene="ytvI"
                     /locus_tag="ACGI3L_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HFG9198737.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            15898..>16227
                     /locus_tag="ACGI3L_003042"
     CDS             15898..>16227
                     /locus_tag="ACGI3L_003042"
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HFG9198738.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSY"
BASE COUNT         6479 a         1807 c         2776 g         5165 t
ORIGIN      
        1 gttaattttt aagttaaaat agtataatat gccatattaa atcatgttaa aactatttat
       61 atagctaaaa tcttacctat ataagtatgt atactatcat ataaaaataa aatcttaaaa
      121 tagaaagggt taaaaacaca gtttattata atttttattg ttgagtagat acgtactatt
      181 atatatgatt gagcaagttt ttcaatcata aatttataaa gtattttgca ttaaaattta
      241 aacaaagaat taaattattt aagattatga ataactaata catttagtaa attactaaat
      301 atacaaaatg taaatactta tcaaaatgta taaatactta tgacatctag ttacttacag
      361 ggtttaagta gaaaaaaata tcaaagtaag tatggcatga tagttgctta tatatttatc
      421 aagaaaggag ttattaagca tggagttgag agataaactt gtaaacatca taaatacaga
      481 aaataaaaaa gatccattaa cagatgttca aatagcaaag tttttaagta caactagaga
      541 gaacataact aatttgagaa aagaacttaa tataagtaat tcaaggcaaa gaagatatcc
      601 ttatttaaaa tcagcaattt cggcaatatt acaaaagaat aagaatattt ctatatcaga
      661 aattacaagg gaattgatga cagaaggctt taatatatcg agaagagttg tggaggaact
      721 tttacctaaa gaaagtttag aaatggatgt agtagaggaa gatgaagaag aatcgaatga
      781 cccatttgaa actctgatag gtaataaagg gagtcttaga aatgctgtag agcaggctaa
      841 atctgctata ttgtatccac caaaagggtt accaacgttg attattgggg aaagtggagt
      901 tggtaagagt ttattttcta gacatatgta tgagtttgca aagcaaaaaa agatagtaaa
      961 agagagctcc aattttgttg tatttaactg tgctgattat agtgacaatc cacaattatt
     1021 attatctttg ttatttggat ataaaaaagg tgcatttaca ggtgctgaat atgatacacc
     1081 aggtcttgta gaagaagctg atgaaggagt tttatttttg gatgaaatac atagattgcc
     1141 tccaaaaggt caagaaatac tattttctat cttagatagg ggaaagttta ggagattagg
     1201 tgaaactaat gctgaaagaa aagtaagtat tatgttgatt ggggcaacta ctgaaaatgt
     1261 agagactaat ttattattaa cattcagaag aaggatacca atgctaataa ctttgccacc
     1321 attacatgat agattactaa aagagaaaat agaccttata tacaatatct ttcaacaaga
     1381 gtgtaataga ataaatgcaa aaatatttgt agataaaaat gtgattgaaa tacttgcact
     1441 aaaaaagttt agtggaaata taggacaatt acaaaatatg attcaggttc tttgtgcaag
     1501 agcttttatg aagtttataa attccaaaga tgaagatagt gaatctatag tagtagtaga
     1561 tataaatgaa gttttaaagc ttaaagattc gtttaaagat gctgcctttc aagagattga
     1621 atatacagag ataagaaaat atttgaaaaa tgctatattt ataccattta atttagaaga
     1681 atcatcagta aaaggaagtc ttttaagtga tgaatatata ttaccagagg acatatacaa
     1741 aacaattgaa aagaaatatt atgacctaaa atccctagac attgaagata tagatataga
     1801 gaatatttta tggactttta ttttaaatag atttgctgac ttaaagttta atcttgatag
     1861 taatgaagaa attttttcaa tgagtgattt aaatagtttt gtaagtgata gtttagttaa
     1921 actggtaaaa gaacttatga atgatatagt tgaaaaaaat atgaatttag aagtaaataa
     1981 aaatatgttc aaatatctag caatacactt agaagaagct ataaaaagaa ttaagctaaa
     2041 tcaaaagata ataaatgtaa atttagaaaa aataaagatt gacttttcaa aagaatatga
     2101 aattagtaaa agttttgcaa taaaaattga ggaatcaatt ggtattaaga tttcagatga
     2161 tgaaattgga tttataacgc tctacataaa gtctgctcta aaaaatgaag tgaaaaaaga
     2221 taaagtaggg ttaataataa tttctcatgg acgtatagct acagagactg taaatgtagt
     2281 taaagaactt ttaggtgtaa agtttcctgt ggctatagat atgcctttag atgaaaaacc
     2341 aataaatata tacaataagg cagtagaatt gtcaaaaata atagaccaag ggaaaggcat
     2401 attgtttttg gtggatattg gttcacttac aaacataggt caaatagtaa ataagagaac
     2461 caatataagt actaaaacta ttgatagagt agacctccta atggcactag aagcaactag
     2521 aaaagtttct atgggagagg aagaacttga tgaaatattt ttttctttgc taaaagatag
     2581 gatgggatat aactatgaat tagaaaaaca catagataaa tcaaatgcaa ttataacatt
     2641 atgtcttact ggagaaggaa ctgctaagta tataagtaaa acgttggaag aaaagtatga
     2701 taacactaaa tgttatcaaa tgagtgcatt ggatgaaagt ttattttgta aaattgaaaa
     2761 tctaaaagag acaaacaata tattagctat tgttgggaca ataaacccta agataccagg
     2821 tataaatttt ataccctata ataaagaact tttcaaaaat ttggatatct atctatcaaa
     2881 atcaaaacaa caagatgaca gaccaattaa atcgtatgaa agaatgcttg atgaggattt
     2941 agtgattttt gaaccagata tatattttaa aaaggattta ttagaatatg tatgttcaat
     3001 tcttataaat aaagaatatg tagaaaaaga ttacttagat tctgttttac atagagaaga
     3061 aatgcttcca acatattcta aaggagctat aggtgtgcct catggagatt cttctactgt
     3121 aaatagtaca aggtttgttt ttgttaaact aaagaatcct attgattggg gtgtaggtaa
     3181 tgtaaatttc atatttatgc cagtttttca ggctaatgat aaagagattg ttaaaaatgt
     3241 tcttgagata ctaaaagatg cagaatttat gaacaatgcc aataagtgtt ttgataaaga
     3301 tgcttttaga aggattatat ttgataaatt taaacatctg tagccatagc aaaaaaattg
     3361 agaggagtta gagtaatgaa tgtagattta atatcattgg gtttagaatc taatgattat
     3421 gaaagtgtta ttgaagaatt aggaagtata atgtgtaaaa aagaatatgt aaaagaaaca
     3481 tacataaatg ctgtcttgga aagagaaagg acattaccaa caggtctaga tattggagac
     3541 atgtgtgttg ctattccaca tacagattca aagcatgtaa atgagtctaa tgtagctgta
     3601 gggatattga aaaatcctgt aaagtttaat tcaatgatag acccaaaaga tagacttgat
     3661 gtagaacttg tatttttatt agcagtaaag aacccagact cacaagtaaa actgttaaaa
     3721 gatttaatgt cagtttttca aaatataaag ttattaaaaa atataaaaaa cgcatcaaca
     3781 aaagaagaag tagctaaatt attggatttt atagaaattt aatgtaggag aattttataa
     3841 ataaaaaatt aaaatttaaa caatcaaagt aagtattatt tttttaatag gtttaatctt
     3901 atataaaata aaaatttaga gtgaaaaatt aggaggaaat tattatgaaa caatttaatg
     3961 tattatcagt ttgtggttca gggacagtta catcatctat ggtagcaggt aaattaaaag
     4021 aagtactagg taataagggg atttctatta ctacaacaga agctagacca acagaagcac
     4081 taaatttagc acaatcagga agatttgact ttataacatt tacgagtcca cttcaaacag
     4141 gcgattatgg aataccaact ataaatgcat ttgcttgcct aactggtata ggggaagagg
     4201 cattctttga agaagttttg actgttattg aagggataga taagtaagtt ttggagacgt
     4261 gaatttatag tatttaaatc aatgatttag atactataat aagctaatat taactaaata
     4321 tttgtggaaa aaacatttta tatgttgtca taaattaaaa aattataaaa atagtcactt
     4381 aagtattaaa ttaagcttat aaatatttat aagtaggagg gaaaaagatg ttagaattta
     4441 tgaaatctat aatcgataca tttggttctg caattatagt tccaattata atattcataa
     4501 tcgcaaagat atttaaagta actactaaga aatcgtttct ttctgctgtg tatgcaggag
     4561 ttgctttaca aggttttaca ctgattttaa attcatttac accagtaata acaccagtta
     4621 tcaataggat ggttgagagt acaggagtaa acctaccagt ttttgatgtt ggttggcaag
     4681 caacatcatt ggttgcattt tcaacaagtg caggtatgat atatttaggt cttggtatat
     4741 tattacaaac aattttattt ttgataaaat ggacagatgt gtttcaacca tcagatttat
     4801 ggaataacta ttcttatatg gtatggggag caatggttat aggagtaaca ggaaattttc
     4861 ctttaggtat agcatgtatg gttttattaa acctatatag tttattaata tcagagttag
     4921 ttgcaaagag atggtctagt tactatagat atcctaattg tacaataata gctatgcata
     4981 atgttgaggc ttctgtgttt gcagtatttg cagaccctat atacaataaa ttgggattaa
     5041 ataaaataaa attaaatcca aaagaattag agaagaaatt agggttttta ggtgaaccaa
     5101 ttactttagg tcttttttta ggtatgttta taggtatatt aggtaatatg acgagaataa
     5161 atactatgga agcttgggga gaaataatga aagtaggtat atctacaagt gcagtgatgg
     5221 caattttccc taaagtagca agtatgtttg ctcaagcatt tgcacctata acagaagcag
     5281 ctagaaagat tatgcaaaaa gctggaaacc gtgagtggta catagcagta aatgatgctg
     5341 ttggatatgg tgaacctgca actttaatat caggtcttat attaattcca ataatgcttg
     5401 taatagctat ggtacttcct ggtaataagg tattaccagt tgtggattta ttggcaattc
     5461 catatatggt tcaaggttta gttgccatac ataatggtaa tataccaaaa gtattagttt
     5521 caggtataat ttggtttgga ttaggattat atgtttgtac atctacagca ccattattta
     5581 cagatatggc tacaaatata ggtgtagcta tacctgcagg agcaatgtta ataacaagtt
     5641 ttaatatact aggaaaacct ttgatgggat tagttttctt tgcatttcta agtgcaaatc
     5701 caatttatat aggtctttca gttgtaattt actttgttct atgggcattg tttagaaaga
     5761 acaaaacaag tattcttgat tatttagaaa aacaagcact taaaaatgta gaagaagagc
     5821 ctgtagcagt ttaagtttat aaaaatgaaa taaaaataat taaaggagtt tataattgat
     5881 tttatataag tatcagataa tacctgagaa atatttaaat gaaatataga cttcttttta
     5941 tttgataata tttgtaatta taatgcattg tatttttata gttgagtttt ctgtataacc
     6001 tgctatttaa aacatactct tttatattta tacagtaatg tggtttaatt ttataaaatg
     6061 taatctctac tggtaaaaga ctttgtatat aaggcatttg cctgaataaa ccatttatct
     6121 tttgtatggc atagatattg ctatatagaa gtatatagca tgaaaggaga tatttatatg
     6181 ggaaataaaa tgagagcatc agtattgtat aatgtaggtg atgtcagata tgaaatggta
     6241 aatataccag aaataacaga tacgcaagtg cttgtaaatg taaaatatgt tgggatatgt
     6301 ggttcagatt tacctaggtc tatggtaagt ggtttgagtg gaaatacaaa atatccattg
     6361 attttagggc atgaattttc tggtgaagtt gttaaaattg gagaaaaagt aaagcatatt
     6421 aatgtaggag atagagtagc tgttgcacca ttagtacctt gtggaaaatg tgattattgt
     6481 aatgaaggta attttggctt gtgtgatgat tacaatataa ttggaacaag agtaaatgga
     6541 gcgtttgcag aatatgtaag agttccagaa gaacatattt taaaactacc agatacattg
     6601 gattatgaaa ctgctgccgg aattgaacca gcaactatag cttatcatgg gatttcaaag
     6661 tctaatatta gagtaggaga tagtgtagtt gtgttaggat gtggtccaat aggtcagttt
     6721 gttatacaat gggcaaaggt gtttggtgca tctaagatta tagcagttga tatttttgat
     6781 gaaaaattag aactttctaa acttctagga gcaaactata tacttaactc aaaagaagta
     6841 aatgtaatca aagaaataaa aaaaataaca aatggtggtg ctgatgttgt aatagaaact
     6901 gctggtagcc gatttacaca agaacaatct ctatttgtag caaaaaagag aggaaatata
     6961 gtgtttgtag gtatatcaca cacagaatta ccacttagtg cagacgctac tgagtgtata
     7021 ttacgtggag aacttacctt gaaaggttct tggaattcat atacaagccc ttatcctgga
     7081 agagcatgga ctgcaacatt ggattttatg gaaaaaggtg acattatttt taaacccatg
     7141 atttcagata aaataggtct taatgaagtg ggtgactttt taagtaaaat gagcaagaga
     7201 gaaattaatt tcaataaaat cctagtagaa atataaaaat ttaataaaaa attctaaaag
     7261 caattaaatt ttataactat gacattaaat aaaataaaaa taattttctt aaataaaata
     7321 taggaggaag aaaagtgtta gaaaatttaa aagaagaagt attaaaagca aacttagaat
     7381 tacctaagaa aaagctaatt acttatactt ggggaaatgt aagtgggata gatagagaaa
     7441 aaggattagt ggtgataaag ccaagtggtg tagagtatag taatatgact gtagaagata
     7501 tggttgtagt tgatttagag ggaaatatag ttgatggcaa attaagacct tcttcagata
     7561 ccccgactca tctagtttta tataaagagt ttgaagaatt ggggggaata gtacatacac
     7621 attcaagttg ggcaacaatt tgggctcaaa taggaaaatc tataccatct tgtggtacta
     7681 ctcatgcaga ttatttttat ggaagtatac catgtaccag aaaaatgact agagaagaaa
     7741 tttgcaatga atacgaaaag gaaactggaa atgtaatcat tgaagaattt atgggaagaa
     7801 atccaattca ttgtccagga ataattgtaa atgaccacgg accttttaca tggggaaaag
     7861 atgcaaatga ggctgtacac aatgcagtag ttttagaaga agtcgcaaag atggcttatt
     7921 atacagagtt aatgagtcct gataatatta tggataaggt tcttatgaat aagcattttt
     7981 caagaaaaca tggaaaaaat gcatactatg gtcaaaaatg attatctgga ggtgaattat
     8041 gctagactct ttaaaaggta aagttgtgga aatagcaatt aaagcagagc attatggttt
     8101 atgtaaagaa aagactggta attttagtat tagagataag gatactggat atatacttat
     8161 aaccccatca ggtgtaggaa gagaagaatt aaaagttgaa catatttgtg tattggattt
     8221 ggatggaaat gtaatagaag ttgagaaagg tattaagcca agtagtgagg tattgatgca
     8281 tattgaaata tacaaaacaa gagaaaatat aaatgccata tcacatactc attctttata
     8341 tgcaacagca ttttcagtag caaagaaacc aattatacca attgtatatg aatcagttaa
     8401 ttatggcggt tatgtagata ttgcttcata cgaaagacca ggaactttaa aattagctaa
     8461 gagtgtttca aaattactga tagatacaga tgcatgctta ttagaaagac atgggttgac
     8521 aactgtaggt aatgatttag acgaagcatt attaaaatca agatatgtgg aagaggtagc
     8581 agaaatatac tataggtctt tagtattaaa tcaatttaaa gaacttgaag tagtagatgt
     8641 tgatgagttt aaatcttgga aatacccaga agaaataaag ttttaatcta aataattttc
     8701 attgaagtgg ttaattaaaa tatatgtatt atttatatca attactatgt tttattatgt
     8761 taattaccgt attttgcaaa tatatttatt acattttttc aaaaaaatat agaatccgaa
     8821 agccatataa aattgacttg ggattctata ctttttattt atgcattttt ctttatctga
     8881 ttttctggag aatttatatg ttcaaaatat tttttagttt cagatactat tataggtgat
     8941 aatgcaagta aagctataag gttaggtatt gccataagcc catttacaat atcagcaatt
     9001 atccaaacaa cttctaactt taagaaagca cctaataaca ccatagccac aaatacagtt
     9061 ctatacccat tcatgccttt tacaccaaac agaaattcaa aacatctttc tccataataa
     9121 ctccatccca aaattgtagt aaatgcaaat aatgttaaac taactgtaag taatattggt
     9181 ccaaatgtag gaattgctcc gttaaaagct gcttgtgtca taacagctcc atttaggtct
     9241 gaacaccaca ctcctgaaat aacaagagag aatccagtaa gagtacagat tataatagta
     9301 tctataaaag tacctgtcat agatataaga ccttgttccg ctggccattc agttttagca
     9361 gcagctgcag ctattggagc actacctaga ccagactcat ttgaaaatac accacgagcg
     9421 ataccatttc taattgccag tgacatagtt gctcctaaaa aaccaccagt agcagcagta
     9481 ggtgtaaatg cacttttaat tattaacata aaagtttcag ggattttatt ccaaaaagat
     9541 attaaaatga ttccacagat tacaacatat ataactgcca taaaaggtac tattttagta
     9601 gctacattag atatactttt aagtcctcca aatacaacta aagctacaaa tactgctaat
     9661 acaacccctg taattctagg gtctatcccg aaactattat ttattgcatc tgttattgaa
     9721 tttacttgag taaaagtacc gattcctaaa agtgcaacta gtataccact tatagcgaaa
     9781 aatattgcaa gaggtctcca tttttctccc ataccattta ctatgtaata cattggccca
     9841 ccagacactt gaccattttt atctttagtt ctgtatttta ttgcaagaac accttctgaa
     9901 tacttagtag ccattccaaa gaatgctgct atccacatcc aaaaaagtgc accaggtcca
     9961 ccagctttga tagctgtagc aacaccaaca atattaccag taccaactgt agcagctaga
    10021 gcagtacata aggctgcaaa acttgaaaca tcaccactac ctttgttttc agcagagaat
    10081 attaacttaa gagctcttgg cagtttagtt atttgaacaa ctccaagctt aacagtaagt
    10141 agtataccag taccaactaa tagtaccagt aggggtggtc cccaaataaa agcatcaact
    10201 ttgtttaaaa tatcaattag attcataaaa acactccctc attttttttg ctttacataa
    10261 tcaatagaat ttttaatgaa gtaattgaca ggaaataagt ataatttatt aataatttct
    10321 agtgtaataa aaaaagctaa atctaaaaaa gattcagctc tggatgtaca ctaattagca
    10381 accaaaataa aagtattagt aaatactgtt tttggtagat aatccctgtc cttttgcctg
    10441 agagattgag cataaaagcc ttgccccttc ggcgcccata atgggtctct ccagagttcc
    10501 gtaaatttta cagtcctact tttaaaagta cctgagagtg ttactccttc ggtgtgctat
    10561 atagcaactc ttctataaaa tcttaaccgg atattgattt gtcatagctt attgtattaa
    10621 taatattaat ataagttttt atgttttgtc aactaaaaaa ttaaaaaaca aagaaaaaat
    10681 ataaaaatgt aagcctattt acgaattata aacttagaaa gatgagtaat atacgtgaaa
    10741 atgaattttg taatacacat acaaatgaag tgtaaaataa gttttaaata aaaaaataat
    10801 aaaatcttaa ataattaatt agatatgatt aaattatggt aatattatag ttacgatatt
    10861 aagaaaagtt ctatttagtt agattttaag cgtaatatga gattatgtat agagaaagga
    10921 tgtattttta gatgggaaaa atattagtgc tagcagaaaa accttctgtt ggaagagata
    10981 tagcaaaagt tttagggtca aaaaatgaaa aaaatggtta tatagagggg ccaaagtatg
    11041 tgataacttg ggcactaggt catttggtta cacttgctga ccccgaaagt tatggagaaa
    11101 gatataaatc atggagctta gaagacctgc caatacttcc caagcacctt aagactgttg
    11161 taataaaaaa gagtggaaag cagtttaata cagttaaatc gcaaatgaat agaaatgata
    11221 tagatgaaat agttatagca acagatgcag gtcgtgaagg agaacttgta gcaaggtgga
    11281 taatagaaaa atcacaggta aaaaaaccta taaaacgtct ttggatttct tcaagtacag
    11341 acaaagcaat aaaagacgga tttgcaaaat taagaagtgg aaaagaatat gaaaatttgt
    11401 attactcagc aatagcacga gcagaagctg attggattat tggaataaat gcaaccagag
    11461 ctttgacaac aaagtacaat gcacagcttt cttgtggaag agtacaaact cctactcttg
    11521 caatgttgct taaaagagaa gaagaaataa gaaatttcaa acctaaagag tattatggat
    11581 tagaattaat tgctacaaag ggaaattcag atataaaatt tatttggaat gataaaaaca
    11641 ataattcttc aacttttagt aaagaaaaga tagaatccac attaaaaaaa gtaaaaggtg
    11701 tagacataaa aatatctgaa gtaaacaagt catataagaa aaaatattca cctgcactct
    11761 atgatttaac agaattacaa agagatgcaa ataaaatgtt tggattttca gcaaaagaaa
    11821 ctttatctat aatgcaaaaa ctgtatgaac atcataaagt acttacttat cctagaactg
    11881 attctagata tttaacatca gatattgttg gaacattaaa agatagaata aaagctgtaa
    11941 atattagtga ttattcaaag atttgtaata gattattaaa aagcaatatt atagctaata
    12001 aatcgtttgt tgacaattca aaggtaacag accaccatgc aataatacca acagaacaga
    12061 aggtattcat gagtgatttt agtgataaag agcgaaaaat atataatctt gtagtaaaaa
    12121 gatttttagc agtactatct cctccttttg aatatgagca gacaactata agtgcaactg
    12181 tagaaggaga aatatttaag gctaagggaa acaaagtaat aaatttaggt tggaaagaaa
    12241 gttataaaga tattgaagat gaagatgagt atgaaagtat accaaatgtt ttagaaaaag
    12301 atgtacttaa ggtcaaggga ttaaagataa cttcaggaaa aacaaatcca ccaccatact
    12361 taaatgaggg aacattattg actgctatgg aaaagaatgg tctagggaca gttgctacaa
    12421 gagcagatat aatagaaaaa ttattcaatt catttttaat ggaaaagaaa aataaagata
    12481 tatatataac atcaaaagga agacaattat tagatttagt tccagtagac ttaaagacac
    12541 cagaacttac agcttcatgg gaaaagaaat tattggatat ttcaaaggga aaacttagta
    12601 aaaatacatt cataaatgac atgaaagatt attcaaaaga tattgtacta gaagtaaaaa
    12661 atagtgataa taaatttaaa catgataact taactaaaaa tagatgtcca gaatgtggta
    12721 aatttatgtt agaggtaaat ggtaaaaaag gtaagatgtt gatttgtgaa gatagagagt
    12781 gtaatactag aaaaactata tcacaagtaa ccaattcaag atgtcctaac tgccataaaa
    12841 aattagaact tcgtggagaa ggtgagggga gactcttcac ttgtagttgc ggatacagag
    12901 aaaagttgtc ttctttcaac aagagaaagc aagaagaaaa acagaaggca tcaaaaaaag
    12961 atgttaatca atatttaaaa aatcaaaata aaaatcaaga gacatttaat aatccatttg
    13021 cagaagcatt agctaagcta aaaaacaaat aattttaaag ttattattat acacaattat
    13081 aactttaact gtatattagt tatatgtact gatataatat agtgtatagt ttaggcatga
    13141 aagtagggct gttaaatgga tttaagtggc atatttaaat actattgtaa agagtgtgaa
    13201 aatacatgga ataattcgag tgttgaatta tttgagaata tagaaacgta tagtaaagat
    13261 tcacaaaaaa agagggaaaa agaattagat aaattgctaa atacaatatc agttcattta
    13321 gagaggtatc caagtgatgc tgtattgaga aaaatgtggg taaaaaaggg cgaggttttc
    13381 ttacaaaaga cattggaaaa agaaaatatt tttaagttag aaaaaatgga tgtagaggat
    13441 agaaaaaaat ttttagatat aacaaaacag tttattagag atgctagaaa atttgatgat
    13501 gatttaccta taggtgatat tatgcaagct atgaggaatg tatggatttc aaatgcatta
    13561 caattattat ttggtaaaga agtatattat tcaaaagcta actttgcata tagtatgtta
    13621 tatccatata ctgataatta tttagacaat acaaatatag ataaaaatga taagatttta
    13681 tttaataact ggttagaaaa aaggctcctg ggagaacaca ttaaatctaa ggattatcat
    13741 gaaagtaaag tatctcaaat gatagattat attgaaagtg tataccctag agaaaagttt
    13801 acagaagttt atgaatcgtt attattaata tttaaaagtc aagtaaatag tttaaaacaa
    13861 catggtaagg aaaatcattt gtgtaaagaa gatttattat ccatttctat tgaaaaagga
    13921 ggttcatccg ttttagtaga tggatattta ataagtggat tgatgacaaa ggaagaaata
    13981 gagttttgta taggatatgg atttttatta caaatatctg atgatttaca agatataaaa
    14041 gaagatttaa aatacaacca taaaactatt attacagaga tgtcaaaaga gggtacttta
    14101 gataaagttg taaataaact aataaatttt actattgagt taatagatag ttttaaaatt
    14161 aataataaaa ataaatctgt aatagctatg ataaagaatg attgcttaat gttaatttta
    14221 ttttctgtag tttataatgc tgaatttttt tctgtaggat atataaaaga agtagagaaa
    14281 tttattccat atacaataga ttattcatta gagattgaag aaaaaataaa agaaaaattt
    14341 aaaaatatag atgttttaaa taatgaaaat gaatataaag aaatgattga tattatttgt
    14401 gcagagtaga aaaaaaggga gtgtcttaga atagactttt tagtttatga ggcactcttt
    14461 ttgtataaaa tcaaatgtat tttcatcatt ttaacaatta aaaagagctt atccctattt
    14521 gagaaagccc tttttaattt aaataaaaat gtcaaggtta aactatttaa atgcagtaat
    14581 aatcccatta tcatgtaagt tttttatgat tgtagctgcg atagggaatc caaataatcc
    14641 agctattcca aatagttgag ctccaacaaa catacacatt aatgttatta aaggatatag
    14701 gccaatttgg tgtcctacta cctttggttc taatatttgt ctaacaacgg ttataattat
    14761 gtatagtatt aaaagtccta ttgctaaatt aatatttcca ttaatgagtg agataatcat
    14821 ccaaggtgtc aaaatacttc ctgtacccaa gactggcaaa atatcaacaa gtgctatgat
    14881 gacagatata gtaaatgcat tttcaacctt taggatagta agtccaataa gtagttctat
    14941 gaatgtcact gatagtagta ttgcataggc ttttagtagt tttaaaagag cattaatact
    15001 gctatttttt atatttatta tcataaattg acttttttct ggaaattgtt ttaagataaa
    15061 gtttactatt ttttgatagt caaaagtaaa gaaaaaagaa gcaattaaag taataataag
    15121 ttttaacata aatgcaggtg ttttacttgc aatactagca atagcattga gtgcatttgt
    15181 tgaaatagaa gctactaaag acatcataga ttgacttata ttatcccaac caagtattaa
    15241 tgctaggtta acattaggtg tactagcatc tatctttgaa aataaagtat ttagcgttgg
    15301 ttgtatactt gatttatata tttcaggaag tctaaaaaat acatcactta cacttgcaaa
    15361 tatcttcaca ccaaagctaa ctaataaaaa tatacacaac ccataaaaaa ttaaaagtat
    15421 tactatagaa ataagtgtac gatttaaatt tgtattattt gtaataagtc ttataatagg
    15481 tcttaagatg gatgcaatga taaaactgat tacaaaaggc attaataatg gcaataagaa
    15541 ttttaataca atatatacaa tacttgttat taaaactaca tatgtaaatt taattataaa
    15601 attcttttgc ttttgaatat ccataatata aaacctccaa tgtatttgat attattctaa
    15661 atatggtctt ttttacagaa aatatactac tgtatattga ttataaacta taaagcttat
    15721 gtaaagtaaa taaattatgt aaaatttagg ttaattttgt ataaagagat acttttatat
    15781 tttacaatta ataaccaaat actaaaaaat attttaaata aagaacttaa aattgtgata
    15841 aaattaattt atagatatta aaaaaagtat aatatatggt ttttaagagg tgctaagatg
    15901 aaaaatttta gagatttagg tgggaacaaa actgaggatg gcagaactgt aaagaaggga
    15961 ttattttata ggtctgcaaa attatcaaat ctaagtgaaa atgatataaa gattttaaaa
    16021 gagttaaata ttaaatatat atttgattat agaagtgatg aagaagctcg taaacatcca
    16081 tcaacaataa tatcaaatat aaaaaatata agaataccag caatgagaga gctagaagaa
    16141 tcaggaggaa gttttggttc tattgaagat atgattgatg gattgtttga aaaagatggt
    16201 gcatttaata tgttaaataa tagttac
//
LOCUS       DAYAKB010000082        16125 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.082, whole genome shotgun sequence.
ACCESSION   DAYAKB010000082 DAYAKB010000000
VERSION     DAYAKB010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16125
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.082"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(242..1114)
                     /locus_tag="ACGI3L_003043"
     CDS             complement(242..1114)
                     /locus_tag="ACGI3L_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9198739.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1508..2086)
                     /locus_tag="ACGI3L_003044"
     CDS             complement(1508..2086)
                     /locus_tag="ACGI3L_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9198740.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2144..2860)
                     /locus_tag="ACGI3L_003045"
     CDS             complement(2144..2860)
                     /locus_tag="ACGI3L_003045"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFG9198741.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3051..3536
                     /locus_tag="ACGI3L_003046"
     CDS             3051..3536
                     /locus_tag="ACGI3L_003046"
                     /inference="COORDINATES: protein motif:HMM:NF013740.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9198742.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     T"
     gene            3547..4131
                     /locus_tag="ACGI3L_003047"
     CDS             3547..4131
                     /locus_tag="ACGI3L_003047"
                     /inference="COORDINATES: protein motif:HMM:NF013740.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9198743.1"
                     /translation="MLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIE
                     FFRTTHDIFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGP
                     FIGAIPPIAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAIL
                     VGQSLFGFIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4286..4945)
                     /locus_tag="ACGI3L_003048"
     CDS             complement(4286..4945)
                     /locus_tag="ACGI3L_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9198744.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5162..6454)
                     /gene="lysA"
                     /locus_tag="ACGI3L_003049"
     CDS             complement(5162..6454)
                     /gene="lysA"
                     /locus_tag="ACGI3L_003049"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFG9198745.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6472..7665)
                     /locus_tag="ACGI3L_003050"
     CDS             complement(6472..7665)
                     /locus_tag="ACGI3L_003050"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFG9198746.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHLVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     regulatory      complement(7747..7915)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(8026..8643)
                     /locus_tag="ACGI3L_003051"
     CDS             complement(8026..8643)
                     /locus_tag="ACGI3L_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198747.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(8813..10513)
                     /locus_tag="ACGI3L_003052"
     CDS             complement(8813..10513)
                     /locus_tag="ACGI3L_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198748.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(10910..11473)
                     /locus_tag="ACGI3L_003053"
     CDS             complement(10910..11473)
                     /locus_tag="ACGI3L_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198749.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11632..12345)
                     /locus_tag="ACGI3L_003054"
     CDS             complement(11632..12345)
                     /locus_tag="ACGI3L_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HFG9198750.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12637..14301
                     /locus_tag="ACGI3L_003055"
     CDS             12637..14301
                     /locus_tag="ACGI3L_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HFG9198751.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLKQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14408..15307)
                     /locus_tag="ACGI3L_003056"
     CDS             complement(14408..15307)
                     /locus_tag="ACGI3L_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HFG9198752.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15334..15972)
                     /locus_tag="ACGI3L_003057"
     CDS             complement(15334..15972)
                     /locus_tag="ACGI3L_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HFG9198753.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
BASE COUNT         5180 a         2683 c         1756 g         6506 t
ORIGIN      
        1 ttgttaatta aggaaatgat attgtttaga gaaataaaaa aagcactctc catgaatgga
       61 aatgctttct ttaataaatt agttgacgta gtaaagatgt attcagaata catctttatg
      121 ttttgagtct cgaaatattt atttgtatta tttaaacgaa aatttatttt ttaagtgata
      181 atcgagtatt tactaataag gctatgattc tcaatttcat agccttatta atatacaaac
      241 tttactcata cacagaatat cttttccaaa tttgctctaa atcatcaaaa tgctgtttaa
      301 tatcttcttt ttccttcatc ccaacagata tagcaagggc atttgaaata ctaagagctg
      361 gaactagaga atctacaaat gaagccatat tactcttaac tagaagagtg ttatctgcaa
      421 gtgatgctac tggcgcaaat aagctatctg ttaatgatat tacatgggct cctttttctt
      481 tagcataatt gacaatttga taagatttct tagaataacg agggaaacta atagcaacta
      541 ttacatcttc ttcatttatt cttacaatct gctcaaaagc atctcccata tccattctaa
      601 ttatatgaac attgtcaagt attatatcta agtaaaaacc taaatattga gctactacaa
      661 aagaactcct cattccaagt atatatattt ttctcgctct taaaagtttg ttagaagctt
      721 ctttaaacgc tctctcgtca atttcttcta gtgtagacct tatattatct atatcacttt
      781 ttaaaacttt gtttagtatt gcaaaatcat cggaataatc atgtgccatt tcaactcttt
      841 gtactgtagt tagtttattt tttatgagtt cttgaagtgc agcttgtaat ttaggatatc
      901 cactataacc taatgcattt gcaaatctta caactgtaga ctcacttact cctacggttt
      961 cacccaattt acatgcagtc ataaatgcaa ctttatcata attatttaaa atgtattgtg
     1021 ctataagttt ttgaccctta ctcaatctcg tatattgaga ttgtatattt gatatcaaat
     1081 gtttactgtc cttcatttca tttgtttctt ccattttttt ctccttttag ttatataaac
     1141 tattttgttt tattaacact gtctttttct ctaaaaattt tattttttat ctcaatttca
     1201 tcttagtttt tatcatagct tcttaaactc ataaaattct aacttttctg taccttatac
     1261 ttcacatagt attttcgatt aaatttatta taccatcttt ccttgcattt tttaatattt
     1321 atccaatatt tcttttaaat ttttcaattt ttactcattt aaaagttatc tatcttattt
     1381 tgcatattta gatgtatatt ttgttttgag aataaactgt tgtatactta ttatttaaag
     1441 tatttttaat aggtcacact atatatatta actcttaata caatcttgtc aagtttttta
     1501 gtatttatta tgcttttttc ttttcaatta aaatcaattg tggtgggtta ttgacttgat
     1561 ttaaaaactt agattctaaa acattaaatt catcttgatt taaattattg acaaggttat
     1621 atatgcaatc tttttcttct tgacctccat catgccctgt atatatggca atgcttatta
     1681 ctccattttc ttttaacatt tctaaactta actttatagc ctttaaagtt gtatctggtt
     1741 tggttataat tgaatgtttc gctcttggaa gataacccaa attaaataaa acacatgaaa
     1801 cttcttcttt tatatattga ttcatttttt catgcccatc aaatatcaat tttactctat
     1861 ctgtatatcc ttctttctct agtttctttc ttgtagactt tattgcttct tcttgtatat
     1921 caaaagcata tacaaagccc ttttctccaa ccttctcagc tagatacctt gtatcatacc
     1981 catttcccat agtagcatca attactatgt caccttcatt tataatattt tctaaataaa
     2041 atttatttat atctgtaatt ttagttaaat actttgcata tgccataata ctatttctcc
     2101 ctactattaa ctttatttca ttttttctca atttattttt atcttatttt attgatttta
     2161 aatattttat ttcatcttct gttaggtatc tatattctcc aactttggtg tcttttaata
     2221 ctattttccc cacagaaatc cttcttaaat ttaaaactgg atgatttata gctttgcaca
     2281 tttttcttac ttgtctattt ctaccctcat gtatagttat ttcacacact gaataatttt
     2341 tttctttatt ttctttagtt acccttattt tggcaggtgc cgttgtgtaa tcttctattt
     2401 ttagtcctgt ttcgaattgt cttatctcat catcacttat aattcccttc acacttgcca
     2461 catacatttt atcaatttca tgctttggat gggtaagctt atatgttaaa tcgccatcat
     2521 tagtaagtat taataaacca ctagtttcat aatctaatct ccctattgga tatactcttt
     2581 cccttacatc tttaagtatg tctattacac tgggtctatt gaattggtct tttactgtag
     2641 ttatatatcc ctctggttta tttaatacta tatatatata attttcactt ggttttactt
     2701 ttttattatc aaattctact atgtcttttt cttcatcaat attaaaagat aactctttta
     2761 ctacacttcc atttaccttt attcttcctc caagaattat ttcttctgct tttcttcttg
     2821 atgctattcc acaagaagct atatacttat taattctcat acttaatcct tccttatctt
     2881 aaattatgtg tgtttaatat ttttatcaat gttaattttg ctacattatt atactatact
     2941 agaccttaat taaaaacaag caaaaaaatt atttaatttt cctaaataat tgtaatttct
     3001 tttcacatac tattaatatg taatagctga ctaaacacta ttttaaggaa gtgattatta
     3061 tttcaaagga aaatataaaa tattatttaa tagtcgtgtt tattggaatt ttatttttta
     3121 aatttattaa tactccatca gactttatat ctagtattga aggattctta aagtttttta
     3181 gcccattttt attagctatt ttacttgctt tacttttaaa tccacttgtg atgctttttg
     3241 agataaaatt caaagcacat agacttttag ccattttttt atcttatata tttataggtt
     3301 ttattttagc ctttgccatt aggttattaa ttccatcaat agctaataca ttaaatagat
     3361 tgataaatga aatgcctatg tatactgatt atatagatag ttttatagaa aaaaatatgt
     3421 caaacatata ttttctaaaa actttaattc ctcatataca acatagttta gataatttat
     3481 taaaagaagc aagtaatttt gttggtaaaa ttcctaaaaa cttcttaatc acttagtata
     3541 tcttctatgc tatttaatat gacaatggga tttatactat ctatatacat tatatatgac
     3601 aaagaaaaaa ttgcattggg atttaagaga tttctatatt cttctactgc tagaaacaag
     3661 gcagataaca ttatagaatt ttttaggact actcatgata ttttctatga ttatttactt
     3721 ggtagaatat tagactctct tattattggt ataattgcat ttttaggatt tcaatttgtt
     3781 atcagaatag aaaatgcttt atttttagct tcaataatat tcttaggtaa tataattccc
     3841 tattttggtc cttttattgg tgcaatccct ccaatagcca tgactatatt atatagtcca
     3901 caaaaaacta tatgggtcat tgcatttcta tttatattgc aacaattaga tggaaatttt
     3961 atagaaccaa aagttatggg taatcaagtt ggtataggag ctatatgggt aatatctgct
     4021 attttggtgg gacaatctct atttggtttc ataggagttt ttctttcagt accaatagct
     4081 gctgttgtaa aaacttatgt tgataaatat atagataatc gtttacaata gattatctct
     4141 actgtgactt taatttttag tttaaaattt aactgctatt tattaaatta tttctcaaaa
     4201 aatatctctt agtaagaaaa aattgctaag agatattttt tataatatat aatttgttca
     4261 ttaaatttat gcatatattt tatacttatt gattatttga gttttgagaa tttccaccac
     4321 tatctgaacc accagtagta tcttgtggag ttggtgctgg tgttggatta ctattatttg
     4381 gcttttcttg attttgagaa gaactgttat tattgtcaga cttattacta tctgattttt
     4441 tatcattgtt tttagaacta gatttattat ttttactact tccactataa gaagatttcc
     4501 ttgcatctga ttcaactcta tacctatctt ctccagccgt atcttttgcc tttttctttc
     4561 tttgttcctc tgcttcgttt tgttcttttt ctaatttagt taactcttct ttctttttag
     4621 ttgcctcttc tttaataaca gaggaaccat ttttgatttt ctctataagt ttaagttcct
     4681 tgattgcacc ctcataattt tttaattctt caaactccgt catatttgac attctcatag
     4741 cttgcatata catagctctt gcattctcat tagtactatc ttcttccagt gcagaggata
     4801 atgattccat agctttttta tagttatgtt tttctaaata tgtttttcct tgctctacta
     4861 aatttatttc atctttttta ttaaatgaac atcctacaag aaatatagat aatatcgata
     4921 ttaataaaat tactcttcct ctcattaaat ccctccttgt catatacttt aaattttatc
     4981 ataattataa agtttttaaa atattttata tttattacaa gaaatttgtt agtaaaacaa
     5041 aaaataagca gatatgctac gaacgataca ataaaccaaa aattaattta gagatacata
     5101 tcctagcaaa tctgctcata ataaacttta atatttaatt tttattatat acttctctat
     5161 tttatatctc taaagctaat aagtcctcat agctttgtct cttacaaatt atcttatcat
     5221 ttccatcaaa tactgatacc actgctgctc ttggtatttt attataattt gaagacattg
     5281 aatatccata tgcaccagtt gatgttgtta taagtatatc tccactttta atatccatta
     5341 tgtttatatc tccaattaat atatctccac tctcacaaca ttttccagct attgttacat
     5401 gattcatagc ctcatgatta attttattca caatactaca ctcataacta gcttggtaca
     5461 acgaaggtct tacattatct gtcatacctc catctacact tacataaacc ctaacatctt
     5521 ttatatcttt tatagaacct actgtataca atgtacttcc tgcatttgca actattgacc
     5581 ttcctggttc tattaccaat gtaggtactt ctattccaag ctctttacat gaagtttctg
     5641 ctttagtgat tatggtttca caaaactctt ttatagtttt aggtttatct ccttcgctat
     5701 aataaacgcc aactcctcca cctaggtcaa tttctgttag ttgtatgttg aatttttctt
     5761 ttatttcttt taccaagttc atcattatat ccactgtatc tatgtatggt tctacatcaa
     5821 atatttgtga acctatatga gcgtgaagac ctacaagttt aatattttta tattcactta
     5881 atttttctat tgctctaaat aaatctccat ttactaaagc aaatccaaat ttagaatcta
     5941 tctgtccagt ttttatataa tcatgtgtat gagcttctat accaggagtt attctaaagt
     6001 atatctcttg agttttacct ttatcttcac ataatgcttc aagcaaatct aattcataaa
     6061 aattatccac tacaaattta cctacaccta aatctaatcc catgtttatt tcttctttag
     6121 tcttattgtt tccatgaaag aaaacttttt ccataggaaa atttgattta taagctgtat
     6181 ataactcgcc tcctgaaact acatctaaac acatttgttc ttcatttata agattacaca
     6241 tgtaaagagg taaaaaagct ttccctgcat aagcaacctt attttttccc tctctagcct
     6301 taaaatattc tatatattct ctacaatttt gtctaactaa agcttcatca aatacataaa
     6361 gtggagtttg atatttttta ctaagttcta aacaactcac tcctccaata tataattcat
     6421 cattatttac agtcatagtt ccatgaagtt tcataatagc ctccccaaat tttatatatt
     6481 aaatacttct gctatttttt ctatagctac ttgcttatca tcagaattta tagcacaagt
     6541 tatacgaatc tctgatgtag ttataagttt tatcattata ccattttcat tgaatatctt
     6601 aaatacttta gcagcaactc cagaagtatt tttcatacca agacctacta aagaaaattt
     6661 agtgatatta ttatcaatca ctaaatgttc ttcatctgta tatttagata ctatcttttt
     6721 acattctccc aactcttctt ttggaactgt aaatgataca cttatcttat ctaaaatagg
     6781 tgcagtttgg cttatcatat ctacacttat acctatagtt gctatatctt caaataagct
     6841 agatatattt tcagctttaa aatcttttat tgttatagaa ctgtcatcat cactagtagc
     6901 taatcctgtt attactttat cctctaattt catgtctttt ccccctctta tatatgttcc
     6961 tttttctgta ccacatgtac gtccgacata gatttcaaca ccatattttt gtgcaagctc
     7021 tatacttctt gaatgcatta cttgtgctcc taaactcgct aactcaagca tttcttcata
     7081 ttcaatctca tcaagtttac tagcctttga atattttctt gggtctgtaa aataaattcc
     7141 atcaacatct gtatatatct cacattttcc atttaattta accgcaagag ctacagcaga
     7201 tgtatctgaa ccacctcttc caagagtggt tacatcacca tcttcgttga ttccctgaaa
     7261 tccagttact atcacgacat ttccttcatc taaactattt ttaattctgt ttacgtttat
     7321 atcatcaatt tgagactttc catgaagacc actcgttttt atatttaact ggtaagcatt
     7381 ataacttata gctttacatc caagtgcatt taatgctatt gataataaag atgctgaaat
     7441 catttcacca gtagacatta aagcatctaa ttccctctta ctaggttcat tactcaattc
     7501 ctttgctaaa gttatatatt catcagtgga ttttcccatg gcagatacaa ctattaccat
     7561 ttgtggattt tcttttcttc gttctattat attttctgct attgatttta ttttttcagt
     7621 atctgctact gaacttccac catatttttg aacaattata ctcatgcttt ctccccctca
     7681 agctaaattt tgataaataa aaacgcccaa aggtatactt tggacgtgta aatttcatag
     7741 accaagtaac cttgtagctc accactttaa aagtgacagc cttatgcata ttctgcataa
     7801 gtccagaaaa tttgtccgtc aacaaaattt cttcggctat ataccctttc atcaattatc
     7861 aacgcttacc agctcctatt gaatactatt gaatacagct acctctaccc taggctcatt
     7921 atttttaatt aatttattaa tatagtttta tcatattcta tataatattg caacaattat
     7981 tttacaaaat gtggcaaatc gatagttttc ttttctaaag ttagcttata tacaattaaa
     8041 tagtttattt aatcctaaat ctataaaatt tatgctatac tcattatcat atctctctaa
     8101 atcatttaat tcggatagat tatctggtgt aactaccaaa acgtttggta ctttaaaaaa
     8161 tggaattgta gatttatcta tttttttaga aagattttcg tatttagaaa tgtctatttc
     8221 attatttaag tcaacatcaa ctaaaacttg ctttatatta ccaaattggt ctgtatattc
     8281 aataaataaa tcgtatttca catcatctac actaacattt cggtaaaatc tttttacatc
     8341 acaacctgca gtattgattc taacaactaa ttctgatcct actagagcct ttattaaatc
     8401 atctccctta aaaagtttac taccgtttaa atagtataca taagagaggt ctttataatt
     8461 ataataatcc acatcacaag gatatttttt tagtgtatat tcactacaca tttttctcaa
     8521 agttttttta aaattttttt tattgtatct tttttggtct ccataaattt ttctaaattg
     8581 agactctgta acacatctaa ccctgctaat taaaagtaat atctcttttt ccatattcgt
     8641 catagtacat tctccttgaa gtattatttg caaagttgta ctaatattat attaatttta
     8701 tgacattaaa tttacaaaga attaaaataa aatagctaat ttttatagaa ttaaattcta
     8761 taaaaattag ctatcactat gttaaatact attatcaatc tttttattta aattatacat
     8821 taccttgatt ttcagaatct ttggaatctg tattttcatc agttcctgtt ttttcttttg
     8881 cttttttatc ttcaaagttt gcaatattta ggttatcaaa ttctgacatt tctattacac
     8941 cagattcttc ttttgaatac gatattttga ctttatcacc aacctgagtc aatggcaatt
     9001 cgctagatac ttttgaagta gccctaaata ttatatcttt atttgaatct aaagttacat
     9061 aataattagt gttaccacct cgcacatctg ggcttattct tgtcactgtg ccttctaata
     9121 cctcatcttt taaatcatta tcaagtttta aatcattacc cttagattct aatgcatcct
     9181 tatagtttct taatgcttca ttcttatctt cacctattcc aagtacatta taatcttcaa
     9241 cagatacaaa tgcaactctc ttaacaagac ccgccttatc ttttaatgat gatacatatg
     9301 ttggctgacc caatatatta tacattacag ggaacgtcgc ttcataattt ttttcttgaa
     9361 cattaccttc agctgatttc attgcagccg tttcagtagc tcctggttgt ttatataatc
     9421 tagcttcttt tgttctagaa tcaactaaca taaatccaat tgtagattca tctccacctg
     9481 aagatgttat acctgtatac caataagacc tgttatcatt gccataaact aatgatgtac
     9541 cttctgttgg tactaaaact cccttttctg atataacaga gtttaaaaat ccattaacat
     9601 aaacacccca gtctttaatt tggtctgtta caaagctttg tggttgtatt ctatccaccc
     9661 atttaggcgt gtttttaaca tcataaacat ttatttttcc agtttctgca tcaacagtgg
     9721 ctattcctgt tgcatttgct cctccatagc caattttatg ttcatataaa cttacaaccc
     9781 aataaggtct tccttcatca tttatttcaa gagtgaaatc tgtcatacca acatttacaa
     9841 taccatgtat gtataaatgt ctttgtaaat cctgatgtaa gtaggcttct ggttggtaaa
     9901 ctatctttat tggctttcca tctatttctt gaactaattg gacgtcttga ggattactag
     9961 ctgatacttt tacataacca cttgtaccac ttagagatgt tatccattta attatgtctc
    10021 tgtgaacaag aggcgctacc cagtacaact ctccatctac attttgtata tgaaattttc
    10081 ctaatttgga tacactccct attgcaggaa cttctccaag ctttttgtca cctaatttca
    10141 ttgccatatc ttcatctaca agacgaatgt catttacact gacagggcta atgtcatcag
    10201 taaatttact ttcagttact tttcccaata gttctctata tgattttgca tgaagtacag
    10261 gtgtagaagt tataaaggga actactacaa tatacacaag caaagctatt gctattgaaa
    10321 aattatattt agccatttta gatgctcttt catttctatc taacatcata tctagtattc
    10381 ctgctacaac aaagaaaatt attcctactg aaaataaaga tgtaaaatct aatcttagta
    10441 caggtaattt aataaatgca taaattatta caattattaa tgcaactcca tatgttttaa
    10501 gatatcgttt catttaatac tcctctctaa aaaatgttat tattactatt atatccatat
    10561 atttacaaaa aataaatatt tatcatattt attatatatt aagatatctt tatatattta
    10621 tagttctgct tattcaacta tatttaacat tatacgtgta tgtataaata ctttttatac
    10681 actgtttgtg ctatccatcc cgcacctaaa ggagtgggat ttttgcacta ttctgtatta
    10741 tatatatcca aaaatgttat aaaaatacaa atattagcag aaatttaaaa actgaagaaa
    10801 gtattctaac taagatttac aaattcttaa tcctatcgaa gttaaactac tatcttcagc
    10861 ctaattatct agcaatattt ttttatatga aaaactctaa atcaagtttt taaatgtttg
    10921 cgatttttga tacataagaa tgttgtctag aattatattc tgataataaa ccttcatact
    10981 ctaaggttaa gccagataaa ttataaaaat catttggcgt tacttcaaat gcttgtttat
    11041 ttaaaatgtc tatctcactt ttttctaaca tgtcagcaac aaaatttgaa catacatatt
    11101 tatattcaga ttgtctctga atattcatta gtaaatatat taatgccatt gtatcgtaat
    11161 agtaatcttc tctataatca ctaattaatt ttatattttt atatagattt tcatattgta
    11221 aattatctac ttctaacgaa tataccctac acacagtgtt ttttcttata gcatataatc
    11281 cttgatttat attttcttca acaaatcctc caataaatgg attccttgga tttagccttc
    11341 caaaagaata cattggtttt agattttcat ttaatgatat tgacacatgt gtatacagct
    11401 ttttacttat attccttatt aagtaagata atatagttcc tgtatatgtt gttacaatat
    11461 agactttatt catcatttcc ccccaatcta gtaactaaat aatattatac acttacaatt
    11521 taatatcata agatattcta acataataaa tgtggtttta caaattttga ttttaaggta
    11581 ctttaatatt atataatata ataaaaatat aaatataagt tttctatatt tttaaccaac
    11641 agatgttttc ttcaaattaa tcagatgatt tagtatatct tgaacctttc cagagtcctt
    11701 taaatatcct aatgccccat ttatttgtga ttttaaatct atttctactt ccatatccaa
    11761 atcaacattt ccttttttta tagatatatt tttaagtgtt attgggtaaa gataactttt
    11821 ttccaaagta atcttatttc cattaacctc aaatggaact tttttattgt agttacttaa
    11881 tattttttct agcattttat cacttagttt aaattttcca attttcacat tctcaagact
    11941 tacaactaag tttccatcct ttaaagtagg tctcaattca agttcatatt gactatttac
    12001 caaaccaaat accttatatg gtcctgctac ctttatttta ccatttttca tttcaacaaa
    12061 attattttca agttcattaa ttccatgctt ctgcatcaat gtatatatta aatttttaaa
    12121 ctcttcctct gaaacagata tttttccaac cattctaagt ggatttttta ctacctccat
    12181 agaatttata tatgagcctt ttgataaata ttcttcatct atgattttat tattttgtga
    12241 actaacatca tatctttctt ttggtgtcaa gatatataca acaattcctg caagtactaa
    12301 aacaataaca attaaactta acaaaatctt tgcaaccttt cccataatcg tctcctttac
    12361 aaatctgtca tcagatttaa aataaattta gataactaac ttcacataat attcttaaca
    12421 atatacatac tataatacag tcttttaaaa attaattcaa ccaatctaat gttttgtaaa
    12481 taaactgtaa aaacatgttt ttagtataaa agttaatatt ttgcataata ctcttaatta
    12541 cacctttatt tttttctaat cttggattaa aattaatatt atgcaataca gtgtagtgtt
    12601 ctgtattata atcaaattaa ataggaggta tagaatatgt caaatgaaac gaactcatct
    12661 aactttataa agaatattat tataaacgac ttagaaacag gaaaacatga cagtatcata
    12721 actcgttttc cacctgagcc aaacggatat ttacatattg gtcatgcaaa aagtatatgt
    12781 cttaattttg gattagctaa ggagtttaat ggaaaagcta atttaagatt tgatgataca
    12841 aacccattaa aagaggatgt tgaatatgta gagtccataa aagaagatgt aaagtggtta
    12901 ggatttgatt ggaacgagtt aaattttgca tctaactact ttgatgaaat gtataagaga
    12961 gctttaatac taataaaaaa gggtaaagct tatgtatgtg atttgacaca agaggaaatg
    13021 agagaatatc gtggtactct aactgaacca ggaaaagaaa gtcctcatag aaacagaact
    13081 attgaagaaa accttgattt atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa
    13141 aaaacattaa gagccaaaat agatatgtct tctccaaata taaaccttag agacccaatt
    13201 atatatagaa tatctcattc aacacaccat aatacaggag ataaatggtg catatatcct
    13261 atgtatgctt ttgctcatcc aattgaagat gcaattgaag gaataactca ctctatatgt
    13321 actttagagt ttgaagacca aagacctctt tatgattggt ttgttaaaga atgtgagatg
    13381 gaaaatatac ctagacaaat agaatttgct agacttaata taaataatac tgtcatgagt
    13441 aaaaggaaat taaaacaact tgtagatgag ggtattgttg atggttggga tgaccctcgt
    13501 gttcctacaa tatccggaat cagacgtaag ggatatactg cagaagcatt gcgcaatttc
    13561 tgtagtgaaa taggggtatc aaaagttaac tctacggtag atagtcaaat gcttgattat
    13621 ttcctaagag aaaacttaca accaaaggct cctcttacta tgggagtttt aagaccttta
    13681 aaacttatta taactaatta cccagaagat aagattgaga tgcttgaaat agagaataat
    13741 gctaaagatg aatctcaagg aaagagatta gttcctttct ctagagaatt gtatatagaa
    13801 caagatgatt ttatggaaga acctgttaag aaatatttta gatttttccc aggaaatgaa
    13861 gtccgtttaa aaggtgctta ttttgtaaaa tgtactgatg taattaagga tgaaaatgga
    13921 aatgtagttg aaatacatgg tacttatgac cctgaaacta agagtggctc tggctttaca
    13981 ggacgtaagg taaaatctac aatacattgg gttgatgcta aatcagctat accatgtgaa
    14041 tttagattat ttgaaccatt aattcttgat gatatacctg aaaatgaagg taaacatttc
    14101 ttaaaacaaa taaatcctaa ttcattggaa atattacaag gttttgttga acctacacag
    14161 ataaaagatg ctaaaccttt tgataaattc caatttgtta gaaatggatt ctttagtata
    14221 gataataaat atacaactga tgaaaaattt gtatttaata gaatagttcc tctaaaaagt
    14281 tcttttaaac caggtaaata atcttacaat caaaaaatga agacttaaaa tataaattac
    14341 ttctactata aataaactta gttagaagta attttttatt tgagtcttca tcatttactt
    14401 taaatgatta acttttttca ctacagattc ccatgacttc tattccatct tttatgcatt
    14461 ctatgttaag aggaaaatct ggtccttttt ctccgtcaat atctgttata agtgaatctt
    14521 cacattctat atgcaccttt ttagttttaa agtatagtat ttcatttcca ttatattgat
    14581 ctaaataatc acctctaagc acacttatca aaactggtat tgattttggt attggcattc
    14641 ctttaaaaat aattacatcc aaatatccat catctatttc agccttatat gctagattta
    14701 tatttcctgc tgttttgcca ttaaaaatca acataagata catatctcca tcataataca
    14761 tttcctcaga agatactttt atcttaaatt tcctcatata caatgcttct tctattccct
    14821 ttatataata agaaattctt ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata
    14881 catccgtaaa cataccagca cttgcaacat ttataaagta cttattattg actttcccta
    14941 tgtctatttt ctttggtttt gaatttatga tttcatttat agcttctttt atatcaaatg
    15001 aaatttgaag agcatttgaa aaatcatttg cagttcctgt aggcaaaatt ccaattggaa
    15061 tttttatgtc taattctttc attgcattta ctactaaatc tacagtacca tcaccaccag
    15121 ctatcaatat gtgttcataa gaactatcaa cttccttaaa tgcattcttt acaggttctt
    15181 taatagttaa tctatagggt atcaataaat aatttttttc ttgatataat tctatgatag
    15241 tgtctaaatt tgataatatc tttttttcac ctgaattagg attgtatata agttttactt
    15301 ttttcattat ttctccttac tcattttatt cttttagtat ccaaaatctt catttaaaaa
    15361 aatcacatgt attctttctg gtgttaattg tctttttata agtgtataac tacagcatat
    15421 tcttcctgga cttgaacagt ctatacatat accagtagtc ttacatccag tatttgtact
    15481 taatctttta caattggctg gagcagctat tgtttttgtt ctttttatag cttcatctac
    15541 atctttaact attttattta ctcctgctat aactattact ttatcaggtc catatatcat
    15601 agcagcaact ctattcccat tcccatctaa attgtaaagt tctccatcct ctgttatcgc
    15661 attagtactt gtaaaataag catctgcaga aaatgacttt ctatatattt ctttcatttc
    15721 ttctggtttg atatcttttg catatctatc aagaaaatta tatttttctc ttataaaatc
    15781 aatcactcct gtttcaaata aggtcataga acctccacat cctactagag aacctgcttt
    15841 aactatttct tcaatttttt taagaagctc ttctttgtta cttactaaat accctttcat
    15901 attattgttt tccaaagatt ttattgtttt ttctattctt ttttcattaa gccaatttaa
    15961 attttgatcc attttaactt cccccttatt tttaatatgc acttaattat ttataaactt
    16021 tattttcttt ataagtttat tttagtacat ctaaaaaaaa atacaatata aaacttaaat
    16081 agttttacat aattttttcc aaaataactt actcaatcaa aaaag
//
LOCUS       DAYAKB010000083        15804 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.083, whole genome shotgun sequence.
ACCESSION   DAYAKB010000083 DAYAKB010000000
VERSION     DAYAKB010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.083"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            138..1094
                     /locus_tag="ACGI3L_003058"
     CDS             138..1094
                     /locus_tag="ACGI3L_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HFG9198754.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1271..1426
                     /locus_tag="ACGI3L_003059"
     CDS             1271..1426
                     /locus_tag="ACGI3L_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198755.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            1556..2569
                     /gene="aroF"
                     /locus_tag="ACGI3L_003060"
     CDS             1556..2569
                     /gene="aroF"
                     /locus_tag="ACGI3L_003060"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFG9198756.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            2591..3655
                     /gene="aroB"
                     /locus_tag="ACGI3L_003061"
     CDS             2591..3655
                     /gene="aroB"
                     /locus_tag="ACGI3L_003061"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFG9198757.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            3655..4968
                     /gene="aroA"
                     /locus_tag="ACGI3L_003062"
     CDS             3655..4968
                     /gene="aroA"
                     /locus_tag="ACGI3L_003062"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFG9198758.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLTFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            4946..6025
                     /gene="aroC"
                     /locus_tag="ACGI3L_003063"
     CDS             4946..6025
                     /gene="aroC"
                     /locus_tag="ACGI3L_003063"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFG9198759.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            6028..7224
                     /gene="pheA"
                     /locus_tag="ACGI3L_003064"
     CDS             6028..7224
                     /gene="pheA"
                     /locus_tag="ACGI3L_003064"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFG9198760.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNRYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSKFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            7271..8080
                     /gene="aroE"
                     /locus_tag="ACGI3L_003065"
     CDS             7271..8080
                     /gene="aroE"
                     /locus_tag="ACGI3L_003065"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFG9198761.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            8092..8625
                     /locus_tag="ACGI3L_003066"
     CDS             8092..8625
                     /locus_tag="ACGI3L_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFG9198762.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            8646..9485
                     /locus_tag="ACGI3L_003067"
     CDS             8646..9485
                     /locus_tag="ACGI3L_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFG9198763.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            9753..11234
                     /locus_tag="ACGI3L_003068"
     CDS             9753..11234
                     /locus_tag="ACGI3L_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9198764.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            11267..14701
                     /locus_tag="ACGI3L_003069"
     CDS             11267..14701
                     /locus_tag="ACGI3L_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HFG9198765.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIVDDGIEKGIWILNDI
                     TDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNVP
                     YSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDED
                     GNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESWQ
                     KPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRRM
                     NQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYNK
                     GTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPIF
                     RKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGIS
                     FVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADKC
                     EKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDRP
                     CNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            14719..15465
                     /locus_tag="ACGI3L_003070"
     CDS             14719..15465
                     /locus_tag="ACGI3L_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFG9198766.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQGKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(15414..15722)
                     /locus_tag="ACGI3L_003071"
     CDS             complement(15414..15722)
                     /locus_tag="ACGI3L_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFG9198767.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
BASE COUNT         6542 a         1536 c         2617 g         5109 t
ORIGIN      
        1 aataaatgta tttaacactt accttataat aaatttaata taaatattaa ataataatta
       61 ttaaaatagt gtaaaataat tacagtaagg attataaaaa atttttagaa tgtaaattga
      121 aatttaggag tagatgtatg tatatactga atttaaatac aagagagact attgaagatt
      181 ttagagataa attttatgta gcagaaaatt cttatcttat attaagtgct ccaaaaaatt
      241 taaaattgct taaggaaact ttggatatag atgaaataac ttttaatgat tgtcttaaat
      301 ttgatgaaat aaccaaactt gatttatttg ataattacga ttttttaagc ctaaatacat
      361 ttgaactaag agatggagaa gctgttatag aagaggtaaa tatgtattta tcagataatt
      421 ttatattggt tgtagtgaat gaagaacact ttttatttga atttgtaaaa aatattattt
      481 tgaagaactc tcaacttgaa aaaaatccag ttattaatct atttaagata aactacttga
      541 ttcttagaga agttataaaa aatggttttg agtctttgga aaaagttgaa gagttaattc
      601 ttcaaataga agatgaaatg atggacaaca ttaataagaa tcatgtatct agaataagtg
      661 atgtaagagg attaacaaga attatagtta agaatactag acctcttttg tatattgggg
      721 atagaatagt taaggaaaat ataagatatt taaaatattc aaatgtaaaa aaatataatt
      781 tagaaaattt tcaaggtata gattttggaa ttgacaaatt atacaatttc gcattgtcaa
      841 cacgagagtt agcagataaa ttattagata tttattcttc cagagtaggt gagaaaacaa
      901 ataacttaat tacaaaatta accttgttaa cagccatatc agcaccactt acaattataa
      961 ctggtatata tggaatgaac tttagatata tgccagaatt aaactggatt tatggatatc
     1021 cagcaacttt attttttatg ctatgtataa tttttgttgg aattataata tttaaaataa
     1081 aaaaattatt gtaaattaca gatgatgttt aattgatttt ataaaaatac atcaattgag
     1141 aagctgattt aagtaaataa aaaaatattt taaattgaaa atatttatag aaaatattga
     1201 caattatatt ttctttgtta taattattaa acaagaagaa taataaatta taaaaatgga
     1261 ggataatact atgaaaggaa tattaaaaga actaacagca aaactttata gcttttttta
     1321 ctttatgttc tggggctttt attttagcgc tggctatttc ttttacaaaa atatatgtac
     1381 ttcctttctg gtgaggcctt attttagtga ttttgagcat aagtaaattt tataaaaatg
     1441 attattttat atatttatat aagatttagt gcttgataga ttattttaga gaactcatta
     1501 gtgagttctc ttttttattt taaatataaa attataatat tgggaggtag taaaaatgat
     1561 agtagtatta aaaatgggag cagataaaaa tgaagttaaa aaattaattg aggctattgg
     1621 gagagaagga gtagaagtta atcccataga tggaacagaa ttaactgttt taggtttagt
     1681 tggagatact agtaaaatag atgccaaaag aatagaagca aataaggtag ttgaaaaagt
     1741 tatgcatgtg gtagagcctt ttaaaaaggc caatagaaaa tttcatccag aaccttcaat
     1801 cataaatgtt aatggaatgg aaattggttc aaagaaaatt gctatgatag ctgggccttg
     1861 ttctgttgaa acagaagacc aaatagtatc tatagctaaa gatgtgaaaa aatcaggtgc
     1921 aggatttttg agaggtggag cattcaaacc aagaacatca ccatacgctt tccaaggatt
     1981 gaaatatgat ggattggatt tattaaaaaa agcaaaagaa aaaacagggc ttcctatagt
     2041 tacagaaata atgtcaacac aagatataga tatatttgaa gaaaatgtag atgtaattca
     2101 agttggagct agaaacatgc aaaactttga tttattaaaa gaattaggta aaacaaataa
     2161 aacaatactt ttaaaaagag gattatctgc tacaattgaa gagtggctaa tgtcagcaga
     2221 gtatataatg gctggaggaa atgaaaatgt agttctttgt gaaagaggta taagaacttt
     2281 tgaaacatat actagaaata ctttggattt aagtgcaatt ttagctgtga agaaacttag
     2341 tcatttacca gttatagttg acccaagtca tgcagcaggt aaatcatgga tggttgactc
     2401 tttatctaag gcagcaattg cagttggagc agatggtcta ataatagaag ttcataatga
     2461 cccagcacat gcactttgtg atggaaaaca atcgattaag ccaaatgaat atgatgaatt
     2521 gataagtgaa ttaaagacta tcgcatcagc agttggtaga gaaatataat ctataaaagg
     2581 atggttaaac gtggaagaaa aactattagt aaatttaaaa gaaaatagct acaatatatt
     2641 tattaaaaaa aatatactaa agaatatagg agaagaaata aaaaaaatat attttggaaa
     2701 taagattttt attgtaactg atgaaaatat agcaaaatta tacttggata aagtaaaaaa
     2761 taatttaagt gaatctggat ttgaaattaa atctttaata ttaaaatctg gtgaagaaac
     2821 aaaatcattt aatactcttc ctaaaatata cgatagttta cttgacttta agttaactag
     2881 aaaagatttg attattactt taggaggagg ggtaataggt gatttaggtg gatttgcagc
     2941 agcaactttt ttaagaggta taagttttat tcaaattcca acatctttat tagcacaagt
     3001 tgatagttct gtaggtggaa aagttggagt tgaccttgag agaggcaaaa acttagtggg
     3061 aagcttttac caaccaaagg ctgtgtttat cgacccaaat gtattattat cacttccaga
     3121 aaaattctat agagatggaa tggcagaagt tataaaatat ggatgtataa aagacaaaac
     3181 ttttttcaat aaacttttaa gtttaaaaaa tagagaagaa gtaatgcaac atatagaata
     3241 cattatacat aaatgttgct ttattaaaaa aactgtagtt gaagctgatg aaaaagactt
     3301 tggagataga atgcttctaa actttggcca tacattaggt catgctattg agaaatacta
     3361 caattttaca ggttataccc atggagaagc tgttgccata ggaatgtata agataacttt
     3421 agaaagtgaa aagataggaa ttacaaaaaa aggtacatca gaacttataa aatcaatttt
     3481 aatgaattat aatttgcctt atgagattga attaagagat aataaatcta tagtagatgc
     3541 tatatctctt gataaaaaaa atctaggtga tacattaaaa ataatacttt taaaagatat
     3601 tggagagagt attatatata atactacttc taaatttttt caggaggtaa gataatggga
     3661 agtctaaaaa tatatccaag taaattatct ggagatgtaa aaataccacc atcaaaaagt
     3721 atggcacata gggcagttat ttgttcatct ctaagcaatg gaaaaagtag aatttctaat
     3781 atagattttt ctgatgatat aatagctact ataagagcaa tgacatcatt aggagctatt
     3841 atagaaaaga aagaagatat tttagaaatt tcgggaattt tttctaaaga aggtatttta
     3901 aatagagaga atcagttgaa tcaacctaaa ttgacaatag attgtaatga atcaggctct
     3961 acattgagat ttttagtacc tatatcttta acatttgatg gtgtaaaaag gtttataggt
     4021 agaggtaatc ttggaaaaag accacttgat acctattatg agatatttga cagacagaat
     4081 ataaaatata gttacaaaga aaatcagtta gatttgatta tatcaggtaa gcttaaacca
     4141 gatgaattta gagtaaaagg aaatataagt tctcagttta tcacaggttt actgtttata
     4201 ttgcctacgc tagaaagtga ttcaaagata ataattacta ctgagctaga atctaaagga
     4261 tatttagatt taactctttc aacgataaaa gattttgggg tagaaattat aaacaataac
     4321 tataaagaat ttattataaa aggaaatcaa acgtataaag cgagagatta taaagtagaa
     4381 ggagattatt ctcaaggagc attttattta tcagcagatg ctataggaga agatattagc
     4441 atattagacc ttaaagaaga ttctcttcaa ggggatagtg aagtagttga aattttatct
     4501 aggatgggaa tggaaatatt aagagaaggc aacaaaataa aaggaataac aaatggttta
     4561 aatggtactt tgatagatgc atctcaatgc ccagatataa tacctgtatt atctgtagta
     4621 gcatccttaa gtatagggag gactacaata attaatgctg gtaggcttag aattaaagaa
     4681 tgtgatagac ttcatgcaat aaatgttgag ttaagtaaac ttggagcaaa tatagaggag
     4741 aaagaggata gtttgataat cgaaggagta agcaagttaa atggtggagt agaggtgtgg
     4801 agtcacaaag accatagaat tgctatgaca cttgcaattg cttcttgtag atgtgataaa
     4861 ccaataatat taaaagattt tgagtgtgta tcaaaatctt atccacattt ttttaaagat
     4921 tttaagatgt taggaggtcg aattgatgag tggaatatgg ggaaataatt taaaagtatc
     4981 aatttttgga gaatctcatg gaaatgctat aggtataaat atagatggtc ttccttcggg
     5041 gattgaactt gaccttgata atattgataa agaaatgaag agaagagcac ctggaaaaaa
     5101 ttctatatct acttcaagaa atgaaagtga tataccagaa attctaagtg gatattttaa
     5161 tggaagaact acaggaacgc cattatgtgc aatcataaga aatagtgata ctcgttcaaa
     5221 agattatgga gagcttaaaa atttaatgag accaggacat gcagatttca caggtaatgt
     5281 gagatattct ggatttaatg actatagagg gggaggtcat ttttcaggta ggataacagc
     5341 tccattagta ttttgtgggg ctatatgtaa acaaatttta tcacaaaaag gaatagagat
     5401 aggagcacac ataaaaaaaa ttaaaaatat agaagatatg agttttgatt atgtaaatat
     5461 ttcaaaacaa cagttatcaa atttgcaaac tttggaacta cctttacttg atttatcaaa
     5521 ggaagaagcc atgaaaaata cgattataga tgcaaaaaat caaggagatt cagttggtgg
     5581 tataattgag tgtgcagtag taggtattaa tgtagggctt ggaaatccat tttttgactc
     5641 tgttgaatct actttatcac atttattgtt ttctgttcct gctgtaaaag gtgtagagtt
     5701 tggtttaggt tttgaacttg cagatatgta tgggtctcaa agtaatgatg aaatgtatta
     5761 tgaaggaaat caagttaaga gcaaaacaaa taacaatgga ggaattatag gagggattac
     5821 tactggaatg ccaataattt tcaaagtggc aattaagcca actccatcaa ttagcagaca
     5881 acaaaacaca gttaatataa aagataaaaa ggacgatatt ttatatatta aaggtagaca
     5941 tgacccttgt atagttcaaa gggctatacc tgtaatagaa gcagtaacag ccattggaat
     6001 ttttgatttg atgaaaggac gataataatg gaggatttaa cgagatatag aaatgagatt
     6061 gacaatatag ataaagagct tattcaatta tttgaaaaga gaatgaatac agttcttgaa
     6121 attgccagac ataaaatgaa aaataacact actatacttc aaaaagatag agaagaaaaa
     6181 gtactaagta gagctgtaga taatttagat aataaagcat attcacaaga aacggtacag
     6241 ttttttaatt ctataatgga aattagtaga ggattacaaa aaagattgat agataatgat
     6301 ggtgagcaga aaatcgagtt tagtttagat tcatcaaata agaaatttga tttgtcaaat
     6361 gtaaatagat ataagtcttt aaaagatgaa ttaaataaaa aaaatatcct agtaggattt
     6421 ccaggaaaat caggttcatt tacagaagaa gcactaaata aattcttcaa caaaaaaata
     6481 tcaaaaaaac aatttaaaga atttgaagat gttttcatag cacttaaaaa taaagaaata
     6541 aactatggaa taatccccat agaaaattca tctacaggag ctatctctga aacttatgac
     6601 cttttgagaa agtacggttt ttatatagtt ggagaagaat gtataaaaat agaccaaaat
     6661 ttaataggga taaaagacac aaagcttgaa gatataaaag aaatatattc tcatccacaa
     6721 ggtataggac aatgtagtaa atttttaaaa caaaatagta catggaaatt gataccattt
     6781 aataacacag caacaagtgc agaacttgta agaaaacttc aagataaaac aaaagcagca
     6841 attgcaagca aaaaagctgc aagtatttat ggattagaaa taataagtcc ttgtataaat
     6901 gatattgcaa acaactatac aagatttgta gtaatcagta atcaaataca cattgaagaa
     6961 gaatcaaaca aaatgagtgt agtattttct gttgaacatg aagcaggaaa actttataaa
     7021 gtacttggat actttgctaa aaataatata aatatgacaa aaatagaatc aagacctatg
     7081 aaaaatgcct catggagata tttcttttat atagattttg agtgttctat atacaatgct
     7141 aaagtgtacg atttattaga attgatagaa cataatacag catattttaa atttatggga
     7201 gtatataaaa ataaaactga atagataaga taaattttta tttaatttat aattattagg
     7261 aggtgtaagt atgaattttt tcggtctagt aggtgaaaaa ctctctcaca gtgtttcacc
     7321 tcaaatccac aagagagtat tcgagatatt gaatattgaa agtgcttata aaaactttga
     7381 aatttcaaaa gaagatatat ctaagctaga cggtgctata aaattattag gaatacaagg
     7441 ggtaaatgtt actgtaccat ataaggagcg tattatgaaa tatcttgatt ttatatcacc
     7501 agaggcaaaa cgtataggag cagttaatac aattttactt agagaaaata tgttatatgg
     7561 ttacaataca gattactttg gtcttgatag tatgtttaaa atggctaata ttgatgttca
     7621 aggaaaagta gcagttatat taggaactgg aggtgcttct aaagctgctc ttacatattt
     7681 tattgattct ggtatagaaa agctttatgt ttcaactaga aaaaaggatg ataaaaaatt
     7741 attaaatagt aaagctatat taatagatta tgaagaactt aaacatataa aaggagatat
     7801 aatattaaat gctacaccag taggtatgta ccctaatgta ggaatttcac cagtgtcaaa
     7861 atctattata caaaattttg atatattaat agatttaatt tacaatcctg gagaaacaga
     7921 gtttttaaga attggtaata gtatgggtaa aaaaacttgt gatggattat atatgctggt
     7981 ggggcaagca ataaaatctc aggaaatttg gcaagatact aaaatagata atagtatttt
     8041 agatgttata tataatgaac taaaattaga atttttgtaa gggagattgt tatgataaat
     8101 aaaacaaaag aaaaattgat attaataggt atgccaggta gtggaaaaac tacaattggt
     8161 aaacttttgg ccaaagaata taattgtagt ttctgtgata tggatgatta tataattcaa
     8221 atatctcaaa aaagtatagc agagttgttt tcagaaggag aagatatctt taggaactat
     8281 gagactcaag catgtagaga actttctata agtgataaaa cagtgatatc tacaggtgga
     8341 ggtgtaataa aaaaggatgt taatatggaa atactaaaag aaacaggtat aataattttt
     8401 attgatagac ctatacaaaa gattttggaa gatataaata ttaattcaag accattatta
     8461 aaaaacggaa aagatagatt gtataatctt tataatgaga gaataaatct ttataaaaaa
     8521 ttttcagata tagagatttt aaatgataaa tcattaaata atgctgtata taatattaca
     8581 aatgcagtca gtgaaaattt taaatttgac tttaaagaaa aataatctag ggggaaataa
     8641 aaataatgaa tattgttatt gtaggactag gagttatagg aggctctttt gctaaagcat
     8701 taaaaaaagc tggatatgaa aatgtatttg gagtagatgt agatttagaa actttaaaaa
     8761 aagcagaaaa agcaaaaatc ataaaaaaag gatgtactac aggtaaagag ttatttaaaa
     8821 aagctgattt aattatatta tctatatatc ctagattagt tgtagatttt ctaaataata
     8881 ataaaaactt ttttaaaaaa gggactataa ttactgatac tacaggaata aaagaaacac
     8941 ttatcaatga tgtgttgcaa attattccag atgatataga ttttatattt ggacatccaa
     9001 tggcaggtag ggaaaaaaag ggtattgatt ttgcaagtga acaagttttt aatggcgcaa
     9061 attatataat tactccaact ggcagaaaca acataaaaaa tttagagtta gttgaaaatt
     9121 taattttaga gattggattt aaaagagtaa aaaagttaac ttcacaaaaa catgatgaga
     9181 ttatagcttt tacttctcag ttacctcatg ttatggcagt tgctcttata aatagtgatg
     9241 aagaaggtag agatacgggt aaatttattg gagatagtta tagagattta actagaattg
     9301 caaatatgaa tgaagactta tggagtgaac tttttttagg aaatagagat aatttactaa
     9361 aagttataga aaactttgaa tcagaagtaa atttagtaaa agaagctata tttaacaatg
     9421 ataaaaataa attaatagag tattttaaaa aatcatcaat aagaagagaa gctttagaaa
     9481 aataaatatt aatatttaag ctatatatag atgggtataa atataagcga tagtgtattt
     9541 aattgtatta ataaatatgg attcaatata attaaatatg ctattgatat atttgtaccc
     9601 ttaactattg ttatctttta aatgataatg atatttattt aaatactctt tattaacaat
     9661 ttataaaact taattgtaaa aaatacttat taatagtaaa ataaagtgaa tcaattatat
     9721 tataattgct aaagagagtg aggtgtagct atttgaaaaa aaatagatta atagcaaaga
     9781 atatatcaat agcatttata gtactattct tttttagtgt atttacattt ttttatgtag
     9841 gtaatattaa tagagtgtta gaatatgaaa caaatgacat aataacagtt acaattgctg
     9901 gatggattat actttcattt ttatttttag gtattataat ttacatatta tattcaaaag
     9961 caaatagtca aaaaactata gaaaaagtag catatacgga ttttgtaaca ggttattcca
    10021 actggagaaa gtttgaatta gatgttacaa atttattaaa gaaaacatca caaaataata
    10081 aatatgcaat ggtcatattc gatattgata aatttaaagc aattaatgat atatatggcc
    10141 ataaaaaggg aaatttaata ttaaaagata ttgcagatac tttaaatgaa ttgactgata
    10201 tcaatgaaac ttttgctcgt gtaagtgctg ataatttcaa tatattatta acatataaca
    10261 aaaaagagga tataataaat attatcaaaa agattatggc aaataatgaa cttgtaaact
    10321 tatcttttgg aatttatgaa atcaaagata aggatttatc tgtaagtgta tatagtgata
    10381 gagcttcact tgcaaaatca tcaataaaaa ataatagtga tgtaaatttt gcatttttta
    10441 atgacaaatt aagagagaaa ttattatttg aagataagat agaaaaagaa atggaatatg
    10501 ctcttgaaag tgggcaattc gtaatgtatt tacaaccaaa atacaatatt aaattagata
    10561 aattttgtgg aagtgaagcc ctagtcagat ggcaatatac agaaaaagag gtcatatatc
    10621 caggtgattt tattcctata tttgaaaaaa atggatttat tagaaagatt gatatgtaca
    10681 tattagaaca agcttgtaaa gaaatccggt ctttatttga taaaggaatt tcacctttac
    10741 ctatatctgt aaacttctca agagttgatt tttttaaaaa agattttatt gaaaacatag
    10801 taaatatatg tgatagatat aaaataccat atagtttaat agaaattgaa attactgaat
    10861 ctagtatgtt tggagatact gatactctat ttaatgttag tagaaaccta caggatattg
    10921 gctttatagt tgcaatggat gattttggct ctggatattc ttctgtaaat atgcttaaaa
    10981 atataccatt aaatgtaata aaattagata gaggattttt tgttgatgat aaagatgttg
    11041 ataagagtca aattgttata aaaagcatag tttctctcat taagcaatta ggaataaggg
    11101 ttgttgctga aggaattgaa acaagaagtc aaatagaaat gttaaaaaaa gcaaattgtg
    11161 atattgttca aggatattat ttttcaaaac cattaccaat taaagaattt gaaaaattag
    11221 tctataaaat atagtcagcg agtcttaaat gggaggtggt gattaagtga taagagcaaa
    11281 atcgttaaaa aatgtactga gtattgtttt aatattttta tttacaataa tttctttttc
    11341 tgattttgca tttaaaacta atgtccagga agaagaaaat agtaaaatta atttaagaga
    11401 aatatcccta caaagttcca atgctataaa aataaaatta gatagttctc tatcctttat
    11461 taaaagtgtg gcaaatatgg tttcttattt taatactata gataactcaa aaatagttcc
    11521 attattagct aatatatcaa aagaatctga ctttcaaaga atctctattg tatctcctga
    11581 tggaataagt cataccagtg atggcaaaat tatcaatgtg tcaaagtatc agtattttaa
    11641 gaaagctatt aaaggagaaa gtaatatatc tgaagttgtg aaatctccaa ttgatggaaa
    11701 agatactttt gttatagcta ctcctgtatt taataagaat aacaaaataa ttggtgtttt
    11761 atacggttct tactacaatg ataaattagc tgaatttata gatataacaa gttttaatag
    11821 tgaagggtac atagatatat ttgaatctag tggtcaattt gttttaaaat cttcacatac
    11881 aaacaaactg attaagtcaa gtagtaacat atatgatata tttaaaaaag cttcttttga
    11941 tgatggttat agctataaaa aaatatatga agatacaaaa aataacaaga gtggctttac
    12001 ctcatatgaa tacaaaggag aaaatcgtta tgctacttat acacccattg gtgtaaatga
    12061 ctggtatgta atttctgtga taccacaata tactgtaaga agaaacattg ataaaataaa
    12121 tcaattagca ttttctctta ttttcaaggt attcttattg tttattatgc ttataatata
    12181 tattatttat aaaaacaata aatctcagaa agatatacta aaagctaaca aagaaatctc
    12241 atctattaca aatagcattc ctggaggagt acaaaagtgt accctgggtg aaacatgcaa
    12301 tattaatttt ttaagtgatg gatttataga gttgtttggt tatacaagag aagaaataaa
    12361 aacattgttt aataatgatt tttatagttt aatacataaa gatgatgttg aaagaataaa
    12421 aaaagaaatt tttaaacaac tttacaaaaa taaaactgtt gaattagaat ataggattat
    12481 aacaaaaaat ggtaatacag tatgggtttt agataaaggg gagcttataa cagaacctga
    12541 tggaaaagaa tatttttgtt gtgtaactgt agatattact agaacaaaac aattagaaca
    12601 agagatggaa caaaaaaatc tagaacttga aatgatatca gaaaatgttt taggtggtat
    12661 aattataaca gaatttaatg atgattttac tataaaatac gctaactctg gttatctttc
    12721 aatgattgga tatacacgtg aacaattaga aaatgaactt aaatacaaag cttgtaatct
    12781 tgttttttat gaggataaaa agaaggctct tgaaagtata caacatcaat taaacacaaa
    12841 aggaatagct gtatatcaac atagaataag aagaagaaat ggtaatatta tttgggtttc
    12901 tataaaagga aggcttattg ttgatgatgg tattgaaaaa ggtatttgga ttctaaatga
    12961 tataacagat ttaaaaaatg cagaacaaaa acttaaaata aatgaagaaa gatttagaat
    13021 tgcattaaag caaacatcaa acactatatt tgagtatgat ataaaaacaa agtcactttt
    13081 aaatactagt aaagagcttg ataaatataa tatttataaa attactaaaa acgttccata
    13141 ttctctagta gaatcaggag ttattcataa agattttagt gatgatttta taaacatgta
    13201 tgaaaatgta ataaatggag caaaaaaagc aagttgtgta gttaagatga aacttccaga
    13261 tgaaaattat atatggaata aagttacctt gactactatt tttgatgaag atggtaatcc
    13321 tgtaagagca attggtatac aggaagatat aagcaaacaa aaggaagcag agataagata
    13381 caatcaagaa ggtaagtatc attcagctat attgtcggaa gcaatgataa cttatgaaat
    13441 aaatgtatca aaggatactt ttatcaaagg aaatgaaagt tggcaaaaac catttggaat
    13501 taagcctgac aataactatt ctcaaatggt aaaaactata gcaaatagta ttgtacataa
    13561 agacaataaa gaaacatttt taaatacatt tttatgtgaa aacttattgg atgcatataa
    13621 aaataatgtg actgaaataa aattagaata tcgaagaatg aatcaagaaa ataaaatgat
    13681 ttgggtcatt tgtacaatgc acttaataaa agattctatt acgaacgata taaaagcact
    13741 tgcttatgtt aaagatattg acaagcaaaa aaatgaagaa attagattaa aattaaaagc
    13801 tgaaagagat actcttacag gattatataa taaaggtact acagaaaaat tgattaatga
    13861 tttcttgaac tctgaggaag caagcttagg aatgcatgca tttttaattg ttgatataga
    13921 taattttaaa tctgtgaatg ataatttagg acatgtattt ggagataaag tattatttga
    13981 agtttctaaa aacctaaaac ctatatttag aaaagatgat atagtaggta gaattggtgg
    14041 agatgaattt atagtattct taaaaaatat tcagtctttt gagaatatca aaaagaaagc
    14101 agaaaaaata tgcgatatat ttagaaattc ttatacagaa aataaaaaga catataaaat
    14161 atctggaaca gttggaattt catttgtacc agaacatgga actgtatttg aagaacttta
    14221 taaaaaagca gacatagcac tttattatgc aaagagcaaa ggaaaagata agtatgcact
    14281 ttataatgat tgtatctacc aaaatgaact tgaaaataat ataagtgata ataatataaa
    14341 attagcagat aaatgtgaga aatccaaacc agtacttaaa gaaattcttg attctattga
    14401 taattatatc tatatagtga atccaaatac ttatgaactt ctttttgtca ataataaggt
    14461 gtctcgtttg gatttagaga taaaattagg agaaacctgt tataaatcac tattaaaatc
    14521 tgatagacca tgtaataatt gccctcttaa cggattagaa gaaaataagc attcaaaatt
    14581 caaaatagag acaaatacat ttggtaaaaa tatcagtata gcaagttgga ttaattgcat
    14641 agatggagaa tacaactgtc ttatagagtg tatagattct tctttataca aaaataaata
    14701 aaaaaggact atgaagatat gttaaatagt ataactttga tacttggtat aatatttaca
    14761 atttactatt tttatctcaa aatagttttt ggaggaattt catttagtga gattttctta
    14821 gttgtaggaa ttgtactaat tatctatcaa atatttaaga aaaaaattaa agaaaagaag
    14881 gttttttata gggtgttaaa aataataatc agcatttttt taatagtatt tgtagttact
    14941 gagagtctaa ttatttttta tcccaaaaat agtttagaat caaaaagtga ttatctctta
    15001 attttaggag cttctgtaaa aaagactaca ccaagtacaa ccctgaaggg taggttagac
    15061 actgcattga aatacctaaa aattaatgat aattgttatg tggtagtatc tggtggtaaa
    15121 ggaagtggag aaaaaataac tgaggcaaaa gctatgaaag attatcttat aaaaaatggt
    15181 atagataaaa ataggataat agaagaggat aaatccacga atacttatga gaattttaaa
    15241 tattcaaaat tgaagataga agaacatagt caaggaaaac taagcgattt aaaagtaaaa
    15301 atagtaacaa cagattttca tgttctcaga agtaaaatat tagcatatag aaatggatat
    15361 aaaaatacgt ctttttatgc tagtaaatca aaactttcat ttgtaccaac ttactataca
    15421 agagaatttt ttgcattatg gaaaacaatc atttttgata gataataaat aaaaagacta
    15481 gatataaact catatctagt cttttctatt cccttaattc taatccattt tccaacttta
    15541 cttgttgtag aaatttcaac attgggattt acaagtaatt gcttataaga agttttatat
    15601 tttacgattc caaaatataa ttttccttca taatccatta taaatccgaa tggtcttact
    15661 cttggtttat tatcttcaac tgtagcaaaa tagaatgttg agttttcttt aaaaaaattc
    15721 attatttttt catgattaaa tcctctttgt atcttatact aatataatga atataaataa
    15781 aatattcata atactaatat aaat
//
LOCUS       DAYAKB010000084        15676 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.084, whole genome shotgun sequence.
ACCESSION   DAYAKB010000084 DAYAKB010000000
VERSION     DAYAKB010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15676
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.084"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..267)
                     /locus_tag="ACGI3L_003072"
     CDS             complement(<1..267)
                     /locus_tag="ACGI3L_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9198768.1"
                     /translation="MAVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAY"
     gene            complement(269..676)
                     /gene="tnpA"
                     /locus_tag="ACGI3L_003073"
     CDS             complement(269..676)
                     /gene="tnpA"
                     /locus_tag="ACGI3L_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFG9198769.1"
                     /translation="MEVTHGRGYVYLVQYHIVWCVKYRHPVLTNEIEEDLINILNKIA
                     EDNKFQILECNSDKDHIHLLINCSPQHYIPDIIKALKGVSARLLMKKHGEQLKKKLWG
                     GHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            complement(1242..1454)
                     /locus_tag="ACGI3L_003074"
     CDS             complement(1242..1454)
                     /locus_tag="ACGI3L_003074"
                     /inference="COORDINATES: protein motif:HMM:NF024570.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
                     /protein_id="HFG9198770.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLD"
     gene            complement(1547..2104)
                     /locus_tag="ACGI3L_003075"
     CDS             complement(1547..2104)
                     /locus_tag="ACGI3L_003075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198771.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHISSR"
     gene            complement(2463..4373)
                     /gene="phnW"
                     /locus_tag="ACGI3L_003076"
     CDS             complement(2463..4373)
                     /gene="phnW"
                     /locus_tag="ACGI3L_003076"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFG9198772.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(4652..5437)
                     /locus_tag="ACGI3L_003077"
     CDS             complement(4652..5437)
                     /locus_tag="ACGI3L_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFG9198773.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(5654..5884)
                     /gene="dltC"
                     /locus_tag="ACGI3L_003078"
     CDS             complement(5654..5884)
                     /gene="dltC"
                     /locus_tag="ACGI3L_003078"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFG9198774.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(5903..7051)
                     /gene="dltB"
                     /locus_tag="ACGI3L_003079"
     CDS             complement(5903..7051)
                     /gene="dltB"
                     /locus_tag="ACGI3L_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFG9198775.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(7051..8565)
                     /locus_tag="ACGI3L_003080"
     CDS             complement(7051..8565)
                     /locus_tag="ACGI3L_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HFG9198776.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(8686..9876)
                     /gene="dltD"
                     /locus_tag="ACGI3L_003081"
     CDS             complement(8686..9876)
                     /gene="dltD"
                     /locus_tag="ACGI3L_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFG9198777.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(10164..11183)
                     /locus_tag="ACGI3L_003082"
     CDS             complement(10164..11183)
                     /locus_tag="ACGI3L_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFG9198778.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(11359..11898)
                     /locus_tag="ACGI3L_003083"
     CDS             complement(11359..11898)
                     /locus_tag="ACGI3L_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HFG9198779.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(11999..12679)
                     /locus_tag="ACGI3L_003084"
     CDS             complement(11999..12679)
                     /locus_tag="ACGI3L_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9198780.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(12708..13997)
                     /locus_tag="ACGI3L_003085"
     CDS             complement(12708..13997)
                     /locus_tag="ACGI3L_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFG9198781.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(14446..>15676)
                     /locus_tag="ACGI3L_003086"
     CDS             complement(14446..>15676)
                     /locus_tag="ACGI3L_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9198782.1"
                     /translation="NKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSVMGGSKDRP
                     PTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKEHDGIYTSH
                     IRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVEIMVDTVPR
                     SSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFILGDRGSIIL
                     LNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRADFPDKLHDD
                     KIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEIVRRVTSLP
                     ARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEYVIVNGKIA
                     LENGEITENKCGEVLKR"
BASE COUNT         5003 a         2855 c         1517 g         6301 t
ORIGIN      
        1 atatgcatta tctaaatctt ttaaggcgtt ttgtagtgaa aatttgtcag gttccttaag
       61 ccattttaat tcttttttta aattggttaa atcagaacta cactgtttat aagtaaaagt
      121 ttctttattg tttttataaa cttctattct tttagcaaga tacttattat atacaaatct
      181 acaacatcca aaagttttgt taattaactc ttgttgtttt ttatttggat acattctaaa
      241 cttataagct ttttccacta ctgccacctc actttacttg ttttttctga ttattaatat
      301 attttcttat ctgttcttct gtattttctg atacagtagc aacgaaataa ctaggattcc
      361 aaagatgtcc tccccataat ttctttttca actgttctcc atgttttttc attaacagcc
      421 ttgctgatac accttttaat gcttttatta tatctggtat atagtgttgt ggtgaacaat
      481 ttattagtaa atgtatgtga tctttatcac tattacattc taatatttga aatttattat
      541 cttcagctat tttgtttaat atattaatta aatcttcttc aatttcattt gttaatactg
      601 gatgtctata ttttacacac catactatat ggtattgtac taaatacaca taccctctac
      661 catgagtcac ttccattttt catcacccaa cataatatta acatagtaat tacttaaaac
      721 aagtattctt aaggttttta tatttatttt taaataacat acgtaagaaa cgcaaatctt
      781 aacttttatc atttttgagg ttgtcgttca cataagttcg ctactaccta tgcagttctc
      841 ttatgaactt cttacacttt catgcaagca cagactatat cttatccttc ggcattatcc
      901 gttaaggtct acccacttcc actaccgata gcttgtagtg tacttccctc aagaggaata
      961 gtcgttgaag tttttcctat tcggagctta cctgctgatt gcccatttta aagtacttag
     1021 gatttaacct tataccatct aaccaatttt ttctactttc gtaactttca cacttaggtt
     1081 tatttcatcc ttatgtttta gtttggttag ctttaggggt ttccagcaat tcaagtagta
     1141 ttggataggt tctatcctat ctctacatat aagtttccct atatgctgac tattttagct
     1201 actaactcat gactaaagtc acaagtgtgc atagctattt tttaatcaag agaagtctct
     1261 tctttcatag acaatattaa ctctattctt tctagtattt tatctcttgg aaagaaagtc
     1321 tcttgacctg taaaagctga tttttttata aaccattcct ctggtattat gttttttctt
     1381 ttccatctat ataattgtcc ataagatata ttagttttgc tcaataaatc tttcttagat
     1441 attaattctt ccatagctct tctagcccac ctttatactg ttttttacag tagaattatc
     1501 tgaaactgat aaattatcac tgtattcaat atttccaaca tcataattat ctactagaga
     1561 tatgcttttt ttctagcata cgaaattttt tgcaataatc tccatgcccc ttttttatat
     1621 ttatactact tgctccaact tcattaaaat tagaagttcc atttaaacta atattaactt
     1681 cttcacaatt caaaaatcca ttacactcca agattccact taaattgata ttttcacaat
     1741 ctatattctc atttgctttt aaatatcctt ctccatgaat aatatccgat tttatacttc
     1801 cttctacatt aataattcca ctagtatcaa tttcaacaga attaatattt cctgtacatc
     1861 taagaagtcc cgatatctca acttttgatg ccagtatgtt tccttctact ttacttaaac
     1921 cagatgtaaa aaattcatta cattctgttg tcccaaaaac ttttgctgaa ccagaagaat
     1981 caaatttact acattttaca cttccttcta ttttgcctgt tcctgatata ttaacattat
     2041 caaaaattcc acctttacat tttccaacac catcaaatct tagtgaactt aattcttcat
     2101 tcataatgat atcctttctt taccgtattt tatctttaaa cctaatataa caaaacattg
     2161 ttacgttgtc aagtatgata ataatactta ataaagcaac tatcatttat tttctataaa
     2221 taggcataaa aataataggg aaatgcttta tttaaactat aaatctaatt tcttagattg
     2281 tggtttaaat aaaatatatc cctattactc aatgtttata tattcattgt ataaacttct
     2341 aaaatataag tctttaaatt ctactgtcaa tactttttat acactgtttg tgctatcatc
     2401 tcacacacct aaaggagtag gctttgcgca ctattctgta acctacaaga cactatcttc
     2461 ttctatctat tgataaattt ttctattaca tcagctagtc tctccatatc agttggatag
     2521 acttcaccta tgctacctat tctaaatgta tctatatcag tcaatttacc tggatagata
     2581 acaaatccat tatcttttaa ataagtataa aattccataa attcaaactt tgcattttta
     2641 ggatataaga aagttgttat tacaggtgat tgagcattat cattcaccaa agtatcaaag
     2701 cctaaagatt ttaatcttga agctattgta aactgatttt ctttatatct agcatatctt
     2761 ttttcaacag aaccttcttc ttccaattct aataaagctt gataaaaagc tcttacaaca
     2821 tgtgtaggtg aagtaaatct ccatttacca ttatttttct ccatagtctc ccattgcgca
     2881 tacacatcaa gagataatga tttagctata cctttacatt tagataattt ctctttatta
     2941 gctattataa aaccaaatcc aggtactcct tgtatacatt tgttagaact actaactaaa
     3001 aaatctatat taaaatcttc aacatcaatc tcaattcccc caaaactact catagcatca
     3061 actatataaa ttttgttata ttcttttgca agtttcccta cctcttgtat aggatttaat
     3121 ctacctgtag tagtttcaca gtgaaccatt gatatatgtg ttatatcctt gttttctttt
     3181 aataaatttt ctactacatt taaatccact gcttctatat ctttaaatgt gcagtcaaca
     3241 aattgtatgt taagataatt acatatatct ttcattctct ttccatatgc tccatttgca
     3301 attacaagaa gtttaccatc ttttgaaata gtacttccta ttatagcttc tactgaaaaa
     3361 gtcccacttc cttgcattaa tacacttgtg tatttatctg tattttgggt tgctagagat
     3421 actaatcttc ttctaacatc ttgtactagg ttattatatt caacatccca agtacaccaa
     3481 tcttttaaca tagatgctct tactgattta gtagtagata gtggtcctgg tgtaagtaat
     3541 atgtaatcat tttctggtac aaaatctgat ttaatagttt cattctctat ttttattagt
     3601 atatcttcta actcagccat agtttctatt acaaaatgtg cacctgcctc tttaaatttc
     3661 tttgaaacta tactcatctt agcttttaat tcttccttat ccatgttctc tacttcttct
     3721 tgtgtaagcc ctaactcact tgaacctttt attacagcaa cactccacat tcctgcattt
     3781 acgccttctt ttacatcact tattgtatct cctactttta ccatagaact cataggagac
     3841 acccctaaag cttcagcatt tttatagcac atccaaggat acggtcttcc ttgagatact
     3901 tctgatggtg ttacaagaaa atcgggtgag tatcctttct ttgctgcatt tggttcaact
     3961 atgttcatca tctctcttgt ataacccgtt gtagaaccta tttttaatcc attttttctc
     4021 aacttttcaa tagtttcaac aacatgagga attggagtcg tatactcttc taatgtctca
     4081 aataacattg gctcaaattc agcataaagt tcatttacat catcttcagt tggcacttta
     4141 ccaaacttat ctgaccaaat attctttatt ctatccattt cacacatttc tcttatatgg
     4201 tctattttta attttcccat aggttttctt gcttcttcca ttgttacatc tatacctctt
     4261 cttttaaata tctctataaa tacattaaga ggtgcaaaac atccataatc tactgttgtt
     4321 ccagcccaat cgaatactac tgcttttatt ttttctccat atatcttttt catatttata
     4381 gcctccatag attcttttta gaatttttgt gtttttaatt gtttttactt ttaaagtata
     4441 actttcatat gttaattata catcatattt aggttaaata tatattaaat ttctgttttt
     4501 agttgtattt agttgttttt attttgtatc atattcccat aaaatcctaa gttacaatct
     4561 aaaatttact ttctaatctt aatctatgaa ctgactatat tttatgaatt tagttgtatt
     4621 gagcatagtt gtattatata aaactaaggg tttattttgc ttctatccat gttatattta
     4681 tctcatttaa cttatccttc cattcattcg gaggttctac atcacaaata acaaaatcta
     4741 attcctctaa atctgctatc ttatacatac tagcaattcc tattttagaa ctatcacata
     4801 atacaaaact ttcctttgaa ttttttatat attcttttga caacaatgcc ttattttggt
     4861 ctatactact aattccaaaa ctatcaagta taccttcact agatataaaa gctttatcta
     4921 cgtataagtt tttcatagta tctattgaca ttggacatgc tgtcctttgg tgttttaaat
     4981 ttacttttcc accaataaat ataacttctc catcaaacaa accttgattc tcataagaaa
     5041 tcaattttga tagaactgga taagagtttg taataatttt taaattgttt acagatatta
     5101 tataatctac aatctgcaaa ttggtagtac cttcatctat gataattgac tcattgtcat
     5161 ttacaaactt agctgcatat ttagcaatac tttgcttttt atctaggtta gtattgtttc
     5221 tctttatatg ttctggttca atcactccat aatttatttt tatagcacca ccatatacct
     5281 tttttaattt attttcattt tctaattctt ccaaatatct tcttattgtt tctgatgata
     5341 cttctaatct ttttactaat tctttagtgt ttaccttccc ttttgaatct aataatttaa
     5401 gtatttcttt ttttctatct atcgaattta aagacattca ttttcctcct aaatataata
     5461 tatttttctc ctataatatt acaatgatac ctaagattta tgaaatcata tttatgtatt
     5521 aaatttttta cttaattaaa gttattttca aaagactttg tattatcatt aaaaaagtcc
     5581 atcaaatatt agtatcagat ggactttgta aaattttatt ttataaatta atatttaaag
     5641 tctaactact aatttatttt cttgtctcca agaattttac taaattattt acagtagaca
     5701 tatcttttct ctctaaatca gttggttgaa gctctatccc taatctattt tcaatttcaa
     5761 gtaaaacttc aattatagct aatgagtcta aaagttccgt ctcaaataaa ttaaggtcta
     5821 aatcttctct tatctcatca gtccctaata catcttcaaa tatttctata actgtttctt
     5881 gcataaattt tcctccttaa aattaagcta aataacctga gaatatcagc aatccaaaac
     5941 acacaatatg gaatgtaatg aaaatctgca ctctctcgaa ccatttatct tttttatgtt
     6001 ttttataaaa tttagatttt cgctgatata tatcagttaa cacaagtgcc aatccttggt
     6061 atacaccata agcaacataa taccaagtta gaccatgcca aaatcccatt gttatcatgg
     6121 ttatcatctg agccacatga gcagcagtag tccttttctt aaatcttttc tttctcattg
     6181 atgacataac aaatctagaa aaaatataat ctccaaacca tcttgaaaga cttatatgcc
     6241 atcttgtcca gaactctttc atatctttac tgataaatgg cttgtcaaag tttataggta
     6301 cttgtattcc aaatatgtat cctgtaccta tagcaaataa actatatcct gcaaaatcaa
     6361 agaacaggta taaactatat gcgtacatat aacttaaaat atttataaaa ctcatatctt
     6421 taggtattct tgatacccaa tatgtattta tcaaaaatgc tataacaaac ttataaccta
     6481 ctcccatgac aatatttttt attcctggca gtaagtattc ttctatatac tcttttctag
     6541 agatttgttt ttccaagtcc tgttcaaatc ttcttgacct atcaataggt ccagaactta
     6601 aagttggaaa aaataacata aaataaagca tctttgaaat tttaacttct tttatagctc
     6661 catcataaat ttcaataacc atttgtatag ttctgaaatt taagtatgat attccaataa
     6721 atccaattat tccaaaagaa gtaactggag atattttatt tattattatt gggagcattg
     6781 atgcaaacaa gaatccccaa tatatgtatt tatttttagt ttttcttctt acatattcat
     6841 atcctttaac tattattact tcaagaataa taaatattac caagtacttt agttggacat
     6901 caattcctac tattaagaat atcataaaca aacttgccaa cataccataa tactttatat
     6961 tcttgcccat tagacctaaa attactgctg gtattgatgt taataataat atataaagat
     7021 aaaaataatc tccatattgt gaaaaaatca ttaaatttcc tccataagtt tctttctgtc
     7081 tattttacca ttgatatttg ttggaaactc agagattatt gaaatatttc ttggaatcat
     7141 atatgaaggt atatactttc caagttcctt ttttattatc atcccatttt taatattact
     7201 taaatcattc ttttcattta actcaacaat accttttaag taagcaattt tttcgtcctt
     7261 atatactggt aaaactactg cattttttac attatgtact tttctcaaat tattttctat
     7321 atcttctatt tcaattctaa atccatttaa tttaatctga aaatcttttc ttccacaata
     7381 atatatattt ccatctaaaa gatatcccat atctccagtt ttataagctc tccactttac
     7441 accatctatt tcatcataga aaaatacttc atcagtcttt tctttattat tgaagtaacc
     7501 tttagaaact gatggtccaa ttattataat ttcacccttt tcattttctt taagctcatt
     7561 tccatcttca tcaagtattt ttattttaca atttgacata gggtatccaa ctggaagact
     7621 tttttcatca tctatagcct tttgagtcat atcatttaca cttacaccaa cagtagcctc
     7681 ggttggtcca tatccattga taattcttgt gtttggaaat ctactcataa gttctttagt
     7741 aagatttttt gaaagtgctt ctcctatgaa tatcattgac tcaaggttag gaagcatttt
     7801 actattaaac tctttttcag ttatacatac tcctgcaaaa gaaggagttg acacccatac
     7861 agctatatct gagatactaa attgtctaaa tagttcttta tagtctgcta atacatcttt
     7921 tgatattgaa aataatgtag ctccatggat aagaccaggg tatattgttg taactgaaag
     7981 gtcaaaagaa tatgctggtt ggttcattat tactttttca cttccatcta tgtttagata
     8041 tgggcttatc caatctgaaa agctatctaa attgtttgaa cttatttgaa ccccttttgg
     8101 ctttcctgta cttcctgaag taaatagtat atatgcattt tcatcatctt ttacccagtt
     8161 ttctttatct aatgattttc cctgatattc atttattata taatttaatt tatccatatc
     8221 aattacattg atatctccaa aatctttttc atcactaaag ttaaataata cctttggttt
     8281 tatctcttta gtgacttcaa aaactctatc aattggaaaa ctaatatcaa gaggcacata
     8341 cgctctacct gattttaaag ctcctatcat acatgccatt atcatgtttt ctttatttcc
     8401 ataaattact ataggagtat cttcttcttt gtatacatcc tttagaaata ctgatatagc
     8461 atctgaatat tcatttaaat ctttataaga aagtttatct ccattacaca ttagtgctgt
     8521 tctatctgta tttgaatatt tttttattcc ttcaataatt ttcatataag aatgctcctt
     8581 taaaatccgt tataaataaa tggcaattct ttaaatggag taaatgttag aactcctatc
     8641 gccaatatta taaccatagt taaacaaata ctagttaaca aatctttatt gttctttaaa
     8701 tattttaaat aatctctcac agacatctac ccatcctttc gtaccaagat gcattacatc
     8761 ccttaaataa tacttatctg accctttatc tttaaggttt agaacttcaa agcctttgct
     8821 ttctgctatt ttttgtgctt tatcgtagta ctgatttctt tctttttcag aaataccagt
     8881 caaattatag aatttatcca tacttgggat taatacaaca actggcttaa tacctaagtc
     8941 agtacataca tttagcatca gtttataatt ttcaaactcc ttagatgtta ataaatttac
     9001 atctttgtct cttcctttgt attgctctat accatcttta aaatgctctt tataatagta
     9061 cttatcaata tttagtggat ttttaccaac tcttttttta gcatcttcaa tggctttctt
     9121 tctctcatat gaccaattta ttggtctttt tctttttgtt gctctctttt tatctagctt
     9181 aattaatcgt ttataaagaa tacccttttc tttaagagct atacaatact ttcttccttg
     9241 aaaataaggc tctaaaagca ccttttcagc tttttcagga aatgtcttag gctcatatag
     9301 cttagcatat aatgcttctg ctttatactc gtcacttccc cataataact tacttgattt
     9361 ttttgcatat tcaatcttat tttgtttaga tatttttgga ttatctaaaa atcgataaaa
     9421 ttgtattggt gaaaatctag actgataatg gtgacttgtg actccgtctt tttccataaa
     9481 ccattgcata gaaattaaca agacaacttt cttattatca atattaggat tcatacttcc
     9541 taatattgca gcatcttgta atgtctgagt ataggctctc ccaattgcaa acaccttatt
     9601 tttactccta tttgtattaa aatagtactt tggatgttgt tttgttgaat tactaagttc
     9661 tgatgacccc aaaatcataa tatccttttc tcttaaaaaa tgattatttg ctgtaacccc
     9721 tttatctttt atatcactta aagtatcatc cataattgga agtagatttt tctccctcaa
     9781 aagttcatca gttttagaat caagaaattt gtctaaccca aataaaaata ctacgcctat
     9841 tataaaaggt gtaataaagt atatcaattt tctcatattt tctctcctct aaaaatattc
     9901 aaatttatgt tattattaat catattagtt ttgatatgta tattcaacta caaaattgta
     9961 ataaaatcgt caaaactttt tttgatactg ttacaaaatt gtaaaaaaaa agaaaaaaac
    10021 gccaaaaata aatttctttt tagcactttt tcatacttat aatttgacat tttaacactt
    10081 ggttaagtat acaccttacc ttaacttaaa attaaattta tttaagaata tatattataa
    10141 attcttatat tttctaatat aaactatata ctatcagctg gataaacaat actactttgt
    10201 cttcttatct catccataat ttccattact attattgaat tttcatgaga atttatattt
    10261 gattctattt tattgttatt tataagactt ataaactcta caagttcata atacattcct
    10321 tctatttctc taggcttttc ctctgctttt tcttttggaa tagatatatc ttcttctctt
    10381 ccatctctgt atttaataat agctttttca aatagattaa gcttttcaat tattatactt
    10441 ccctcttctc cttgtatttc agatggtata taagaatcag ctactttaga atactgaatt
    10501 atcgcatcca tatcatcata ttgaaataca gctgaacctt ctccatccac tccagtttga
    10561 agtatatgag aaactgcctt tacagttttt ggagcaccaa ataaattcac cataggatgt
    10621 atacaataca ctcctatatc cattaaagct ccatttgaca actctttttt aaaggcattt
    10681 tctataattc catttttata tttatcatat cttgaagaat actgacaata gcttccaaaa
    10741 aatcttctta ttttccctat tttatataag ttttctttaa ctgctttaaa gtttggaaca
    10801 catgtaattc tcatagcttc cataagcaat acattattat ctttggctgt ttttatcatt
    10861 gatttgactt cttttaaatt agatgctaac gacttttcac aaagcacatg ttttttgtgt
    10921 tttaaacaag taatggtttg ctttgaatgt aatgcatttg gagaagctat gtatacagca
    10981 tctatatcct tcgatttagc catttgttct aaatcatcaa aaaaaatact tgctccatat
    11041 agagttccaa attctctagc tttttctaaa tttctagaat atacagcaac caattcaaag
    11101 tctttaaccc tagatgcagc tcttagaaat atatttgcta tattgcttgt cccaacaata
    11161 ccaaatctta ttttacccat cataaatcac tccccatttt ctacacttta ttttaatttt
    11221 aataaaaaac tttacaactt atagatatat tataaaataa ttttatcaaa taaaaaagaa
    11281 agctaatttt aaatgatttc accattttaa catagctttc ttttaactac aatctaaatt
    11341 caacttatat ttttaaagtt atctttctac tatatcttta tttcccctca aaaattttat
    11401 agtaagaatt tcatccacaa acaatgttac taaaagtata gttacaacaa ttggccaata
    11461 aggtattata agactatata aactatcaac tatatacact tgaaaatatc taactccaat
    11521 aaatgtcaat atagtccaat atacagaaaa ctttagacat actattcctc tactattgta
    11581 cttataatct gaataatccc aatagacctt attaaaatat actttcataa gtattcctgt
    11641 aatatattct actactgtcg gcactactag acataataaa agcaatgcaa atatattatt
    11701 ggggtcaata aatcttgaga cctctattat aatcgacatt gcaattgcat acattggttt
    11761 aaatggacca tttaaaaatc catcttcttg aaaatgccct tgtttataat aactatataa
    11821 gttttcaatt atccaaccta taaaaccata caagaaaaaa ttaaataaaa aatataatag
    11881 agaacctaca ttatccatga atattcctcc tagctgttta tacttatttt ttctcatatt
    11941 catggattta ttctaaatca aagaaattat atttaattta tttaattaat actttatatt
    12001 atagattgtg acattcttta gagttcaaac tttttaggta ttctctaact tccagtaaat
    12061 tttcaagtat cttatgtgat tgtgatttaa tttgctcatc tggctctttt aaatctggta
    12121 catttataca tcttatacca ccattgtatg cagcttcaac tcccataggc gaatcctcta
    12181 tgacaataca attttgggga ttaacattta tctttttagc tgcttttaag aatatctcag
    12241 ggtttggttt agagtttaca acatcatctc cacaaactat agcatcaaag taatctttta
    12301 aatttgcctt agctaatctc tttactgctc tttctctctt tgttgatgtt gcaacagcca
    12361 ttttgtatcc attttccttt aaaaaagaga ttagttcatt gactcctaat ttgataggag
    12421 ctcccttcct ctccataaat tcaatcatat ttttagtttt ttcgtcatat aaatctatta
    12481 ttggtacaga actatcgtat atatctgtaa gaccttctat tattccttta cgatttcttc
    12541 ccataactga tgtataaatt tccttagtca tagtatatcc atacttttca aacgtctcca
    12601 tccaaaattc aagagaaatt ctctctgagt caaacaaaac tccatccatg tcaaaaataa
    12661 ttccttctac tttttgcata caattcctcc aatatttttt gatataatta tattacactt
    12721 tttatgatta attttacaac cctcaattta tccaattcta atattgtaaa attgtaattt
    12781 tcaaaagtta cactttggtt tactttaata tttgaaccaa gcatatagga tatccaccca
    12841 cctatactgt caaatccatc atgctctata tcaagtccaa aatacttatt aatatagttg
    12901 atagattcag ttccatcaac taagtaagaa cctgctccta ttttcttaat atgagtctct
    12961 tctttgtcaa attcatcttg aatttctcca actatctctt ctagtatatc ttctattgtt
    13021 accacaccag atgtaccacc atattcatcc acaactatag caagttgaag tttttccttt
    13081 cttattctct caagagcttt atctatagtt aaattttcag atatatatat aatatctctc
    13141 aatatttctt ctagttcaat tttattttca tttatctttt gattgtataa atctcttata
    13201 tgtacaaaac ctaatatatc atctttattt tttctgcata ctggatatct tgtaacacct
    13261 tcctctttta aaatagctaa tatcttttct tcagaatcac tttcatatat acataccata
    13321 tcagttctag gaaccattat ctctctaatt ttcttttctt caaattcaaa aatattatca
    13381 actaatcttt gctctgattc atctataagt ccacttttat aactttcttc tactaatagt
    13441 cttatttcgt cacctgtatg gggttcatca acctcatcag cttgtgaata tccaaatggt
    13501 ttaagaaata aatcagtact taagttgaaa aaatatatta ttggatatgt taacttataa
    13561 aatcctacta ataaaaaaga tgtactcaac attatttttt ctgtattata aagtgctaaa
    13621 gctttaggaa ccaactctcc tattacaacc tccatcattg ttataattaa aaaagaaatg
    13681 gaaattgata tagtatatat aatactttca ctaagattaa atacacttac tattggtaaa
    13741 attaactctt taactgtaga ttctcccatc caacctaatg caagtgaaca aagtgttata
    13801 ccaagttgac atgcagaaag ataggaattt aagttgtctt ttattatttt acatcttttt
    13861 gcattattat taccttcagt tatcatggta tcaatcctag aactacgaag ttttaccata
    13921 gcaaattcac aagctacaaa aaaagcattt atcaaaacaa gcattactat aagtgttact
    13981 tttaataact cccgcataaa gtattggttc ttataatgta agaaatctat aagaactcaa
    14041 agttcccccc ttatattaat aaatttaatt tataatatat attctatcat atttattaat
    14101 atatcctact ttattacaaa taatttttat aaactaaata acccctttta atatttatga
    14161 ctggctattt gataaatatt aaaggggtta tttagttatc attttttatt tctaaaaatc
    14221 ttttctcaaa tgatttagtt atctatttat ccaatttttt acataattta atgattaaaa
    14281 atattaattt tttcactata aagtataaat attatctgat tattaaaata aatattaata
    14341 ctataaataa aaacgaagca tgatttttat ttaaataaat ctcaaacttc gtctttactt
    14401 acttagatat ttatttactt tctaaatcct attattttta aaaccttatc tttttaatac
    14461 ttcaccacat ttattctcag taatctctcc attttctagc gcaatttttc catttacaat
    14521 tacatattca acaccattgg ctagtaattg tggctttgaa aaatcaatat cttctgacct
    14581 aggataacta tagttatcca tgtcaataac tgctatatca gctatcaacc cttctttaag
    14641 aatacctcta ttttttattt taaattgcct agctggtaat gaagtaactc ttcttacaat
    14701 ctcttccaat ctaacaccag actttctgta catattgaag aaaattggaa aagctcctct
    14761 tctttgtagt tcaaaccatg acatatcccc acccacacta aacaaacaat ctgaaccaac
    14821 cataacaaat ggattatcaa ttattttatc atcatgtagt ttatctggga aatcagctct
    14881 atacattcct cctaaacaaa agataagttc ttcgtctcca tctaaaagta aatcgagtaa
    14941 taacttgtcc tcatctattc ctttttgtgt agctatttca cgtattgatt tcttttccat
    15001 attaatatct ttagtgttta gaagtattat actcccccta tctccaagta taaatgcttc
    15061 ttttaatata agtgttcttc cctcttcatt tctaagagca tccattaccc catctatacc
    15121 taattcaaat agactagatg atattgccat aataaattga attactcttt ttttcttcat
    15181 acaatgccca gaacttcttg gtactgtgtc aaccattatt tcaacaccat tatacctagc
    15241 ctttaatatc tcatcaaatg cttctatttc aactggactt aagtgagata cttgaaccct
    15301 agcaccactt ttctgcccaa cctctatggc ttcttttact gcattatatc ttcctatgta
    15361 atctctaata tgagatgtat atataccatc atgctcttta atctgccttg caatatcaac
    15421 aagttcatca atatcagcat acttacttgg tatatatgcc aatccagtag atattccaaa
    15481 agcaccactt ttcattccat catttattat atctgtaatt tcattttttt ccttttctgt
    15541 aggaggtcta tccttagaac ctcccataac actccatctt atagtcccat gccccaacaa
    15601 gaatcccata ttgacagaaa taccactttt agatataagg tcacaatatt ctgtaaaatt
    15661 attccaacat ttattt
//
LOCUS       DAYAKB010000085        15581 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.085, whole genome shotgun sequence.
ACCESSION   DAYAKB010000085 DAYAKB010000000
VERSION     DAYAKB010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15581
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.085"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            465..1244
                     /locus_tag="ACGI3L_003087"
     CDS             465..1244
                     /locus_tag="ACGI3L_003087"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFG9198783.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1554..2429)
                     /locus_tag="ACGI3L_003088"
     CDS             complement(1554..2429)
                     /locus_tag="ACGI3L_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9198784.1"
                     /translation="MLVYYLYNLIFLEGGVITLKLKIVGSGGMSIIPSSFCKCKICEE
                     ARQKGGRYERLGPSLYIDDIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGI
                     RIVEKIGCDFITGENNPIGFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKI
                     NNFDIDLINNNPDRNITFYVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDD
                     GILNDGTKLKDTPFKDEIFTLDEIVEIKNYYRIKKIIVTHIDEMWGKSYGYYSELEKK
                     LDNIYFAYDGMEIIV"
     gene            complement(3385..4203)
                     /locus_tag="ACGI3L_003089"
     CDS             complement(3385..4203)
                     /locus_tag="ACGI3L_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9198785.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4371..4952
                     /locus_tag="ACGI3L_003090"
     CDS             4371..4952
                     /locus_tag="ACGI3L_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9198786.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4949..5137
                     /locus_tag="ACGI3L_003091"
     CDS             4949..5137
                     /locus_tag="ACGI3L_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198787.1"
                     /translation="MKIITIGSSLITVLLFLSTMICGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYI"
     gene            complement(5307..7049)
                     /locus_tag="ACGI3L_003092"
     CDS             complement(5307..7049)
                     /locus_tag="ACGI3L_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloendopeptidase"
                     /protein_id="HFG9198788.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            7478..8854
                     /locus_tag="ACGI3L_003093"
     CDS             7478..8854
                     /locus_tag="ACGI3L_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HFG9198789.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            9165..9836
                     /locus_tag="ACGI3L_003094"
     CDS             9165..9836
                     /locus_tag="ACGI3L_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFG9198790.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            10025..10822
                     /locus_tag="ACGI3L_003095"
     CDS             10025..10822
                     /locus_tag="ACGI3L_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFG9198791.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
     misc_binding    11166..11400
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11450..12469
                     /gene="pheS"
                     /locus_tag="ACGI3L_003096"
     CDS             11450..12469
                     /gene="pheS"
                     /locus_tag="ACGI3L_003096"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFG9198792.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            12486..14879
                     /gene="pheT"
                     /locus_tag="ACGI3L_003097"
     CDS             12486..14879
                     /gene="pheT"
                     /locus_tag="ACGI3L_003097"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFG9198793.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            14904..15494
                     /gene="zapA"
                     /locus_tag="ACGI3L_003098"
     CDS             14904..15494
                     /gene="zapA"
                     /locus_tag="ACGI3L_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFG9198794.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
BASE COUNT         5922 a         1851 c         2545 g         5263 t
ORIGIN      
        1 tttaaatata atcaatactg attctacaat attattaata ctacttttta taatataatc
       61 aatactgatt ctacaatata attaacacta cttttttaaa tataatcaat attgattcta
      121 caatattatt aatactactt tttacaatat aatcaatact gattctacaa tataattaac
      181 actacttttt aaatataatc aatatcgatt ctataatatt aacactactt tttataatat
      241 aataaatact gattctataa tataattaac actacttttt aaatataatc aataccgatt
      301 ctataatatt aacactattt tttatgctat ataacaatta ttgaaaatga tataaatata
      361 atatctcaaa taatatgaat ataacatctg aatagagggt gttttatttg taaaaaataa
      421 gtttacagtt tgagcgtata aacttatggt aaaggagaat aattatgagt tataagaaga
      481 ttgcaattat aacgggtgct aatagtggtt ttggtaaaga gtttctaaag ttattaataa
      541 atgaagaaga aataacagaa atatgggcag ttgcaagaaa caaggcgaga ttaaatcaat
      601 tagtagatga atttggaagt aaggtaaaaa ttttttcaaa agatttatca aaaatagaag
      661 aagtaaaaga aattggtaca tttttaagta aagaaaatgt atgtataaaa taccttataa
      721 acaatgctgg ttttgcaaaa ttctgttcat acaatgattt aagtatagat gaatctatta
      781 atatgattga tttaaatatt agtgctgttg tagcattggg acttatatgt attccatata
      841 tgcaaaaggg aagccatatc atgaatattt cttcacaagc atcattccag ccattgccat
      901 atcaaaatat ttatagttca actaaagcgt ttataagaaa ttatacaaga gcattaaatg
      961 ttgaacttaa gagtaaaggg ataaatgcaa ttgctgtatg tccaggttgg atgagtacaa
     1021 atctatttaa gagaggtata gttgtagctg aaaaagggac aaaaaatttc ccaggcatag
     1081 tgtctccaga cgttgttgcc aaaaaagcat tgaaggatgc aaagaaaaat aaggatattt
     1141 ctgtgtatgg tataaataca aaatccagtc atttattagc aaaactattg ccacaaaaaa
     1201 tgatgatgaa ggtttggtta atgcaacaac atattaagga ataagagttt tggtaattaa
     1261 gtatcagttg gagattcaat ctgttatata ttatgagaag ttttgttgag caaataataa
     1321 ttgtgacaaa acggcttatc tagtgacgat aagccgtcta taatgtatat aaaatatatt
     1381 tttgatttta ctttatttag atattgaagt attaaaatat gtaggacttg aaattttata
     1441 aagataaata ctatgatatt ttgtaaaaac tgcgatatgt tgatatcaca tagtttgact
     1501 atactgttaa attgaagttt tcttattttg cattatgctt attacttaat gatttagact
     1561 ataatttcca taccatcata tgcaaaataa atgttatcaa gtttcttttc taattcactg
     1621 taataaccat atgattttcc ccacatttcg tcaatatgtg taacaataat ttttttaatt
     1681 ctataatagt ttttaatttc aacaatctca tctaaagtaa atatttcatc tttaaatggt
     1741 gtgtctttaa gttttgtacc atcatttaat ataccatcat cagaaactag acttattatt
     1801 aaaatatcag catcaaagta catatcacta tgagtaaatg gcttgggatt acagcaggca
     1861 tatatgactt ttttttcatt ctctttgata acatagaagg ttatattcct gtctgggtta
     1921 ttgttaatca aatcaatatc aaaattattt atctttacat gcgaagtttc attaatagaa
     1981 atgcaattta taacatcacc ataatattta agacaatcga gattcgttcg gtttatatct
     2041 tcaattactt caggaagcgc ataaaagcca attggattat tttctcctgt gataaagtca
     2101 catcctattt tttcgacaat tctaataccc ttaacatggt ctgggtcatg gtgagaaatt
     2161 gaaatatgtt ttacttccga tattttttgt ctgttacaag ctactgcaat gtcttcaggt
     2221 gtgtctatca gcatttttat atcatcaata tataaacttg gtcctaatcg ttcatatctt
     2281 ccgccttttt gcctggcttc ttcacatatt ttgcatttac aaaatgaact tggaataatt
     2341 gacataccgc cactaccaac aatttttaat ttcaaagtta ttacaccacc ttctaaaaat
     2401 attagattat ataaataata tacaagcaca actgattaac aaaattatga gttaataaat
     2461 tatatcacat gtaaatatga aagaatagta tgaaattttt ataaacatat attaaatgtt
     2521 tctcaatgaa attgactttg tatatgaact gaatgactta ttcaatatgg ataagacatt
     2581 tttcttgtaa taagatatga ttgtcctata aggtttatgt aattttgata taatttgata
     2641 taatatattg attaacaaca tacatgttat tggtgagcat atttctatag aatggaatat
     2701 ataatttttt atatttatca ttgtattatt gtacaaagaa agttaaaaag agtagagtac
     2761 aaaggaatta tttgtacttt actcttttat tgttttgtta aaaaaactaa tttatattag
     2821 tgattaaaat atatttaact agagtataag gatagtatat aatcttataa ttgatttatc
     2881 tgacaaatta agataatatc ctaatcaaat tctagtcatt taaacataaa atcataattg
     2941 atttatctga caaattgaga taatatccta attaaattgt aggtatttaa acataacatt
     3001 ataaataatt tatctgacaa attaagataa tatcctaatc aaattctagt catttaaaca
     3061 caacatcaca attgatttat ctgacaaatt aagataatat cccaatcaaa ttctagtcat
     3121 ttaaacataa catcacaagt gatttatctg acaaattaag ataatatcct gattaaattc
     3181 tagtcattca aacataacat cacaagtgat ttatctgaca aattaagata atatcctaat
     3241 taaattgtag atatttatac ataacactaa aagtaatttg tttaacaaat taagataata
     3301 tcctaattaa attgtaggta tttatacata acactaaaag taatttgtct aacaaattaa
     3361 aatattatcc aattaatata aaaattactt ctttttaact gggaagcata cctctgttac
     3421 ccaattatca ggattactat cgttgccagg acttacatga taaatattaa acataggacc
     3481 atccacatca tagttattat ctgatatcca attaccaata gcctcacaag cgtctgcaac
     3541 ttgattgaaa tttccattaa caattgcagt tgcagcagtc acacttggaa cagtcttaaa
     3601 tttaacatgt tcagtatctt tatactttcc agatacagca acttgtactt caacatctac
     3661 ataatcttct ttatatccag tatcataaaa aactgcttta gaatactttg ggggttcaat
     3721 ttgaacattc tggtcttttg tctctaaaaa tgcttgatgc cataacattc cttcgtcttg
     3781 ataagttggt ataacccttc taagtgtcat catatatttt ggtgcaaaat tctttatagt
     3841 tacatcataa tttttcataa tatcatttcc tccaattctt ttaatagtgg tttctatttt
     3901 taatagtttt ttctgtgtat cttctaattg ttcttttact tgagaatggt ggatatttag
     3961 atattttatg agactttctt tatcgttata ttctgtcaaa atttctttta tagaatacaa
     4021 gccaaagccc atatctttta gtgcatggat tctgtttgta gtagaaagtt ggtctgcact
     4081 atagtatcta tatccattag ttttattcgt atgagaagga gttaaaagtc ctatttcatc
     4141 ataatgacgt aacatacgaa tactaatttt acttagcttt gaaaaatcgc ctatcttaaa
     4201 catgtttttg tctcctttat aaaggtactt ttagcttaat attaatataa accatatcat
     4261 aatgttagag tcaactaaaa ttataattaa attatattga catatgatga aaaaaatatt
     4321 atactgaaca tgttcagaac tgaaaatgtt aattgttttg gaggtctatt atgaaaagta
     4381 atgataaaga tgctagagaa cgtataattg aagttacatt gaatctttta aatgaagtag
     4441 atgatattga ggagattaca gttagaaaaa ttgctgagcg tgcaaatgtt ggagttggtt
     4501 taataaatta tcattttaaa acaaaggata atttgttgag tactgccata ggagatgtga
     4561 tgtcaaatat aatagcagag ctatatgacg atagtgtata tactctaaga cctattgaag
     4621 atttaaaaaa tttattaaaa aaattgtgtg atactggatt acattatgaa aaagtgcttc
     4681 cttttgtatt gaatcaatgt ataaccaatg gagatatgca agcagaactt gatattgtcc
     4741 ctatgcttcg taaaattttt ggaaataaaa aagatgaaat gagtctaaga attattgccc
     4801 tgcaaattat tttaccaata cagatttctg ctttatctac agaatcattt cagttataca
     4861 gtggtataaa tataaagaat aaatatgagc gagataaatt cattgatatt ttaatagaaa
     4921 atattattgg agaggatgtt gatgtaagat gaaaattata actattggtt caagtcttat
     4981 cactgtttta ctttttcttt caactatgat ttgtgggttc tggattaaga ataataaggt
     5041 aacagatgca agttctatta agttccatat gaatagtgct atttttacag ggatattttt
     5101 attgatttcc acaatccttt taattatata tatataaaaa taataatatt attaataaat
     5161 aaagtatcag aaattataaa gacaagagtc ttaaaaattt ctgatacttt accatataat
     5221 tttattaaac attaattgtg tgtgaaaaaa tatcacttat ttcaatctaa tactaaatct
     5281 taagagtgag tataaagtat tagaaattaa gaagcatttt ttagttcaag cggattatct
     5341 ataccaaaat aatcatataa agtagagctt atttcctcta aatttccatc ttggaaaggt
     5401 aattgtaaat ttaccttttc taccacatct ttaaatccag catcagtatt ttgatttaaa
     5461 aaatccatat atacatcaac agcttttctg taatcttctt gtgataattg ccatatctga
     5521 agtgatacat cagatgcaag accataactc aagtaataaa aaggaacttg gaagttatga
     5581 gatacaagta tccaaaaagg agcatttttt tctctaagta tattattgga aactccatat
     5641 tcttcctcta aatcaaaaaa caatttattg atatcattta gactcatata tggattcttg
     5701 tatataattt cttgaaattc atcataaaga caagcatcaa taatagtatt taaaacaatc
     5761 gataagtgtt ctttttttat agcttcagat tgtttaccaa aaaaatcatc aaaatattta
     5821 taaaatagaa tttctaaaga tgttgaatga acttcacata catctatact tggttgcatc
     5881 ttattgttta agttaatact gttgtagtaa ttataaaaat gaccaaactc atgagcaaaa
     5941 ctagtaacac ctaaaaaaga attatcccat gtattaaaca agaaaggtgc tttatattta
     6001 tttatataag tagtatatcc tccaggtgat ttgttttttc cagaagaata atcgtacaag
     6061 tcatattttt tcatatagtc gaagctctct tttagttttg gagatatatc ttcaagtact
     6121 ttatcaaact tcctaaatga gcgattttta tatactttaa tataaataga agaatcagat
     6181 ggtttagatg aaatctctct atataatgga actatgtaat cttttacatc ttgtctaaat
     6241 tttttagctt cttcttgaga atagtctttg tttaggttca tataggcata atctatataa
     6301 ttcttaaatc cttgcttact tgctatttca gttcttgtct gtataagttc taagaatatg
     6361 ttaccaaata taggattgta tttttttaag taatctgaat aaattttcac atattcttca
     6421 gggctaagat ttggtcttga caaggcttct tcaaagtcta cctctatacc atctattgat
     6481 actgtagatt tagctaataa gtcttcatat tttacaacta ggtcttgctc ttttttaagc
     6541 aaaccttcaa cttctttaga attaagtttt ccaatgttct ttagataatt aaatgtatcc
     6601 tttccaagtt ctttttctaa ttctttagag aatttagaag ttacaaatct atcttgaaag
     6661 tctttgtatg acatgtcaac atctactgat ttactcataa gatacttata ttccttagag
     6721 taaaattcgt ctgatgaatc tatgttattt ctaatttttg ctatagtaag tgtactgtaa
     6781 aaatcttgat aaattttatc aacttcatta aataaattta attgttcctt agctgtttta
     6841 gctgttaaaa gtttgtcgtt gcacttgtta atgttttcgc aaattgactg tatattagga
     6901 cgcttatatt ccattttttc aaaaggaata gttcctctaa cagaatcttt ttttgtatca
     6961 ttagtataat ttcttatgta tgatgcaaat ataataaaaa ctgcaattaa aattagaaaa
     7021 acaaatattt tcttcttgga tttaaccata aaaatcctcc aatcatggat atagttatta
     7081 attattttac tatattaaat ataaaaaatg catgttaaga aaatttaaca taaagatata
     7141 gataagatta taaataatat aaaaaattta acttcaaaaa agtatatgaa atttatactg
     7201 gtaaaatgat aaataaattt taagtacaaa atagtaaaag ctatgatagt tttagaccta
     7261 ttatatgtaa aaaatataga tgtttttggt gcaatttaaa ttaaaagata tatataaaaa
     7321 tttaaaatat tccaaacaga aattataaaa attactatca ttgtctttat acaatattta
     7381 tactataata gaataataat ttagaggaaa gctctaaaaa taaacaaatt aagggtctta
     7441 acagtagtga ttttatgtta aggaggtata aagaaagttg aaaacaatag ttagaagact
     7501 tattctctac gcagatggaa tgcgtcctac tcaaataatg gtatctgggt ttgctgcgat
     7561 tattgtaatc ggagcattgt tgttaacact cccgatagcg tcgcagagtg gagagagtat
     7621 aggcttatta aatgctctat ttacggctac ttcagcggtt tgtgttactg gtctagttat
     7681 ggtagataca gcaacttatt ggagtttatt tggacagata gttataataa cattgataca
     7741 aattggtggt cttggattta tgaccgtagc cacaatgttt tcacttatgg cacgaaaaaa
     7801 aatacaacta agagaaagat tattaataca agagtcatta aatcaagctg atttatcggg
     7861 acttgtaaga cttacaagat ttgtattaat aataaccata acaatagagg gaataggtgc
     7921 actggtttta tcaactgtct ttattccaca atttggtttg tctaaaggga tatggtatag
     7981 tgtatttcac gcaatatcag cgttttgtaa tgccggattt gacttgatgg gcagtgtaag
     8041 tggcccattt acatcgttaa attcttatgt aaacaacttt acagtatcaa tgactgtttg
     8101 cgcacttata gtgcttggag ggctaggatt ccctgttgta cttgatattg taagaaaaag
     8161 aagattttca aaattaaatg tgcattctaa ggttgtattg ttttcaactg ctacacttat
     8221 ttttgtgggt gcattattta tttttcttat agaatttaat caaaaagcta ctatggcgga
     8281 cttgccttta aagggaaaag tactatcagc aatatttcaa tcagtaacag caagaactgc
     8341 tggttttaat acgcttgatt tagctacttt acgagaaagt agtgtatttg taatgataat
     8401 tttgatgttt attggagcat cacctgcatc aactggtggg ggtataaaaa caacaacact
     8461 agctgtttta atcattacag ttagaagttt tctatcagga aaatcagata tagaagcttt
     8521 tgaaagaaga ttagctccat caactataaa aaaatctctt ggtatatttg taatcagtat
     8581 atcagcagtt atttttggaa cattgattat ttcaataact cagcctaatt ttacattagt
     8641 tcaatcagct tttgaggtta catcagcact tgctacagtt ggttcaagtt tagctggaac
     8701 tccaaactta aatgctttag gtaagattat aataataatc tttatgttta tgggtagagt
     8761 tggttctctt actttattta tggctatact ttctggtggt agaagaaaga gtcaaccaat
     8821 cagatatgca gaaggtaaaa ttatggttgg ttaagttacc aaggagtagt ataaatttat
     8881 aatgggttta gagtagcact gtaaatctgt tgataaaata aatgagccta gatgtaatta
     8941 tatgaagaaa taaaatcaac taatgaacaa aattaattaa tgaaataaaa aaacagggaa
     9001 ataaaataca aataaaaagg taaatcaaaa ttaaattaat ctgtgtgtat aaaattatat
     9061 attgtgtata agttttgtat gtgtaaagta tataagtttt gtatgtgtaa acaattaatt
     9121 taagagatat tatataaatt gtgtattagg gaggaagttt cgagatgaag caatatatag
     9181 tcattgggtg tgggagattt ggaagttcag ttgcgtctac tatgcatctt ttaggacatc
     9241 aagtaatggc aatagacaaa aatgaagatt cagttcaaag tatatctgac aaggtaaccc
     9301 attcacttat agtggatgtt actgatgagc aagcgttaag gtcattaggt ttaggtaact
     9361 ttgatgtagc agtagttgca ataggttctg atataagggc atctataatg gcgactctta
     9421 tagccaaaga aatgggtgta gagttgataa tatgtaaggc aaaggatgaa ttacaagcta
     9481 aagttcttta taaaattggt gcagatagag ttgtatttcc agaaagagat atgggagtaa
     9541 gagttgcaca caatttagtt tcggataata tattagacca tattgaactt gacccagagt
     9601 attcaattgt tgaaatcgta actccaaata gttgggttgg caagacactt atagagcttg
     9661 aattaagagc tagatatgag ataactgtac ttgctataaa aacaggtaaa aatataaatg
     9721 ttacaccttc tccagatgag gaacttacag ccggaagtat cctagttata atcggtcaaa
     9781 atactagtat aacagcgata acatctggaa ataaggggat aattagaaga agataattta
     9841 ctatttaata tatatttaat tgcaatgaaa gcagatagta tcatataatt atgaatagtt
     9901 atatgatact atttttttaa tcgaaggtag tatttatttg taagattaga taaagagaag
     9961 ttaaattaaa agtaaggagg ctgtgctaat ataaaaattt ataagttatt agcatttaga
    10021 taaaatgatt acaaatataa acagtaagga taatgaaaag ttaaagtata caagagcact
    10081 attaaaatca aagaatagga ataaagagtc aaagttcata atagaaggat acagaatagt
    10141 aatgcttgca cttgaatgta tggcaaacct tgattatgta tttatcaatg aagaatttga
    10201 aaataagaaa gaacatgtaa aactattaga agatttggat aaaaaaaaca caaagatata
    10261 caagactact aataaaaact ttaaagaatt agtggataca gaaaatactc aaggaataat
    10321 aggtgtagtt tcatttaaga aaaaaaaatt aagtgaaagt ataaataaaa aagataaatt
    10381 tgtattgatt ttagacagaa tacaagaccc aggaaatatg gggactataa taaggactgc
    10441 tgattctgct ggagtagatg ccataatagc actaaaggga tgtgtcgata tatacaaccc
    10501 aaaagtaatt aggtctacta tgggttctat ttttgatatg aatataattg atgcttcaca
    10561 agatgaaact gtggacatgc ttaaatcatt ggattttaat atagtttcaa gttacttaaa
    10621 tacagaaaat ttttatgaca aaatagatta tggctcaaaa gtagcattgg tgataggaaa
    10681 cgaagcaaat ggaataaatg aagaacttgt atcaaagtct gatattttgg ttaagatacc
    10741 tatatatggt aaagccgagt cgttaaatgc tgcgataagc tctgctatac tgatgtatga
    10801 aataaaaaaa tacttaattt aatgtattgt aataaatata atgtcatgtt ataatcttga
    10861 attaaatagt agagtatcaa aaatagtcaa tatatattaa aaaaataatt aaattaatta
    10921 tatattagat gtatattata taaaaaataa ttgagttaat tatgcattag atgtatatta
    10981 tataaaaaat aattgagtta attatgcatt aggtgtatat tatataaaaa ataattgagt
    11041 taattatgca ttagatatat attatataaa aaataattaa attaattatg tattggatat
    11101 atattaaaaa tagtcacata atttgaatgg aaatgatata atactaaaat aaacaatata
    11161 atattgtaaa tgcaatgaaa gaggaaagta ttttgattaa acttagtaaa gagataaaca
    11221 cctaggctgg gagtgttttc taagaggtca tgagaagttc cctctggagt aacagagctg
    11281 aaattttaca gtaggctttg acgtcaaaaa cgcgttaagt ttgttagagg tggtttgatg
    11341 atttttaaat tgttaaacta ctagggtggt accgcgaaac tatagccttt cgtccctaga
    11401 cagggattga ggggcttttt ttatacaaaa aaacgaaagg gtgatatgtg tgcaagaaaa
    11461 attacttgct ttacgtgaag cagctttggc tgaaataaaa gaagcacaaa gcatagaaag
    11521 tgtagaaagt ttaagagtta agtacttagg aaaaaaaggt gagataactg ccatacttaa
    11581 agaaatgggt aaattatctg ctgaagaaag accagtagtt ggtaaggttg ccaatgaggt
    11641 aagagaaaac attgaactta gcataaattc taaaaaagaa gaaataaatg ctattgaaaa
    11701 agaaagaaaa ttaaaagagg aagtgataga tgttactcaa ccaggaaaag ttttaaaggt
    11761 tgggaagaag catccaataa ctcaaattat agatgaagta acagatatat ttatcggaat
    11821 gggattctct atagcagaag ggccagaagt tgagactgtt gaaaacaact ttgacgcatt
    11881 aaacgctcct aaagaccatc catcaagaga tatgagcgat acattctata tcaatgatgg
    11941 ggtattactt agaactcaaa catctccagt tcaagtaaga actatgagaa gtcaagagtt
    12001 accaataaaa gtaattgcac caggtagatg ttttaggtca gactcgccag atgctacaca
    12061 ctcaccaatg ttccatcaga tagaagggct tgttgttgga aaagatgtta ctatggcaga
    12121 atttaaagga actatggata tcttcgttga aaaattgttt ggttctgata tcaaaactaa
    12181 gtttagacct cacaacttcc catttacaga accaagtgca gaggttgatg ttacttgttt
    12241 caaatgtggt ggtaaaggtt gcccaatgtg taaatatgaa ggttggatag aaatattagg
    12301 ttcaggtatg gttcatccaa atgtgcttag aaattgtgga atagacccag aagtttacag
    12361 tggatttgca tttggagttg gggttgaaag acttgcaatg cttaaatacg aaatagatga
    12421 tattagatta ttattcgaaa atgatatgag attcttaaat caattttaat taggagggta
    12481 tgtagatgtt agtatcttta aaatggctta gagactatgt tgatatagac atggatgtaa
    12541 aagagttcgc tgataaaatg acaatgacag gaactaaagt tgaaacaata gattattatg
    12601 gtgaagaaat agaaaatata ttggttggaa agattttaga aataaaacaa catccaaatg
    12661 ctgataagtt ggttgtaact aaagtagata ttggagataa agttgttcaa atagttacag
    12721 gagctacaaa tatatcagaa ggagattata ttccagtagc tgtaaatggt tctaagttac
    12781 ctggaggagt tgaaatcaaa cagactgatt tcagaggtga attatcagat ggtatgatgt
    12841 gttcagcagc tgaactaggt atagatgaac attacattga ggagtataaa agaggtggta
    12901 tatatatttt agaccacgaa gattcttatg aattaggaaa agatataaaa gatgttttag
    12961 gattaaaaga tgctttaata gattttgaat taacttcaaa cagacctgat tgtaaatgca
    13021 tgatgggtat agctagagaa gcagctgcaa ctataggaac aaaagtaaaa tatcctgaaa
    13081 tcgaagtaaa agaaagtgac gaagagatag atttcaaagt tgagatagat aatccagatt
    13141 tatgtagaag atatgttgct agaatggtta cagatgtaaa aatagaacct tctccatatt
    13201 ggatgcaaag aagacttaca gaagcaggag taagacctat aagtaacata gtcgatataa
    13261 caaacttcgt aatgttagag cttggtcaac cacttcatgc ttttgatata aatcaagtag
    13321 agactggaag aatagtagta agaaatgcta aagatggaga gaaacttgta acattagatg
    13381 atgttgagag aacattagac aaagatatgc tagttataac aaatggagaa aaatcacttg
    13441 gtttagctgg tgtaatgggt ggtgctaact cagaaataac ttctaatacg aagactgtac
    13501 tttttgaaag tgccaatttc aaaccagaaa acataagaat gacagctaaa aaagttggta
    13561 ttaggtcaga agcatcttca agaaatgaaa aagacttaga ccctaatctt gcagagatag
    13621 cagcaaatag agctgcacaa cttgttgaaa tgttaggagc aggaaaagtt ttaaaaggtg
    13681 ttgtagatgt atatccaaat aaaccagaac ctaaaaaatt ggtagtaaat cctcaaagaa
    13741 ttaaccacct attaggtgta gatgtaccaa tggagcagtt tgtaggaatt ttagaatcat
    13801 tagagtttaa atgtaatttg gtagctaatg ataaattaga aatagatgta ccaagcttta
    13861 gaacagatat ggaacaagaa gctgatgtat gggaagaaat agctagaatt tatggatttg
    13921 agaatatacc ttctgtacaa ttagaaggaa atacgacagc aggaattaaa acttcaaaac
    13981 aaaaattcat ggatgcttta aaagataatt caactgctgt aggattaaat gaaatattaa
    14041 catattcatt tgtaagccct aagggagtag ataagataag agtaccagaa ggtaatgcaa
    14101 agagaaattt tgttaaatta cttaacccat taggagaaga aacttctgta atgagaacta
    14161 ctttaatacc aaatatgtta gatgttttat caactaatgt atctcataaa atagaagaag
    14221 tatctgcatt tgagtgtgga catatattca tcccacaaga ttcagaatta cctaaggaag
    14281 aaaatagaat gtgtgtaggt atgtatggta aagatgttga cttctttgca ctaaaaggaa
    14341 ctatagaaac tatacttgta aatgtcggat ttaaaggtta tgaaattgaa cctcaagata
    14401 ataatactac cttccaccct ggtagatgtg ctaaaatagt gtataataat aaatatgtag
    14461 gtacattagg tgaattgcat ccagatgtta tagaaaacta caatctaggt caaagagttt
    14521 atgtcgctga aatagatatt gactttgtat ttgataattc tgatagaaca aagaattatg
    14581 tgccattacc aaaatatcca tctacatcaa gagatatagc tcttattgtt aaagatgatg
    14641 tatttgtaaa acaaatagaa gatataataa aggaaaatgg tcaaggatta gtagaaagct
    14701 acaagttatt tgatgtttac aaaggttctc aaatagaagc tggatacaag tcaattgcat
    14761 attcaataac ttatagaagt aaagataaaa ctctaacaga tgaagatgta gctaaggtgc
    14821 atgataagat attaagtgaa ttaagcgaaa aattaaatgc taacttaaga tcaaattaac
    14881 aactaatgtc gggggaggtt aggatgaaca aagtaatggt taaaatccat ggcgctgaat
    14941 atccaatggt tggagacaaa tcagagaagt ttatgattag tattgctgat tttgtagaca
    15001 aagaaatgga taaaataaca cgtcaaaacc cgaaattgag cttatcagtt gctgcgatat
    15061 taactgcatt aaatatatca gaccttttat ttgaatgttc agatgagaat gagaagttga
    15121 ttaaagcgaa tgaagaattg agtaagaagg ttggagcatc taatgaagag cttcaattag
    15181 aaatcaaatc tttaaagctt acgatagcag aaaaagaagc agaaaatcgt gaagctgaaa
    15241 ctaagatgaa agagttaatt gagattatag aaaataaaaa gcaagaaata ttcgaactta
    15301 gtaatacgac agaaggttct agagcagagt tagatgctta taaaaacaag attgaggagt
    15361 taagtactca acttgaagaa gcaaatgaaa gagctactat agctgaaaac ttagcttctg
    15421 agtttcaaaa caaagcttat gatttacagt taaaatgtac agggttaaat aatgatgcaa
    15481 aaaatgtgga ataaactaaa agatttgctg tctcttgttt tttgagacag cttcttttaa
    15541 tgtataaata taaatgctat ataaatatag ataatgttta a
//
LOCUS       DAYAKB010000086        13915 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.086, whole genome shotgun sequence.
ACCESSION   DAYAKB010000086 DAYAKB010000000
VERSION     DAYAKB010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.086"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(189..650)
                     /gene="ribE"
                     /locus_tag="ACGI3L_003099"
     CDS             complement(189..650)
                     /gene="ribE"
                     /locus_tag="ACGI3L_003099"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HFG9198795.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(755..1948)
                     /locus_tag="ACGI3L_003100"
     CDS             complement(755..1948)
                     /locus_tag="ACGI3L_003100"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HFG9198796.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(1971..2636)
                     /locus_tag="ACGI3L_003101"
     CDS             complement(1971..2636)
                     /locus_tag="ACGI3L_003101"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HFG9198797.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSNNHKSNIDKDFLFK
                     NGF"
     gene            complement(2670..3782)
                     /gene="ribD"
                     /locus_tag="ACGI3L_003102"
     CDS             complement(2670..3782)
                     /gene="ribD"
                     /locus_tag="ACGI3L_003102"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HFG9198798.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKASNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(3914..4035)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            4224..6707
                     /gene="recQ"
                     /locus_tag="ACGI3L_003103"
     CDS             4224..6707
                     /gene="recQ"
                     /locus_tag="ACGI3L_003103"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFG9198799.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      6796..6907
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7049..8350
                     /gene="thiC"
                     /locus_tag="ACGI3L_003104"
     CDS             7049..8350
                     /gene="thiC"
                     /locus_tag="ACGI3L_003104"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HFG9198800.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            8404..8598
                     /gene="thiS"
                     /locus_tag="ACGI3L_003105"
     CDS             8404..8598
                     /gene="thiS"
                     /locus_tag="ACGI3L_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HFG9198801.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            8591..9394
                     /gene="thiF"
                     /locus_tag="ACGI3L_003106"
     CDS             8591..9394
                     /gene="thiF"
                     /locus_tag="ACGI3L_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HFG9198802.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            9457..10227
                     /locus_tag="ACGI3L_003107"
     CDS             9457..10227
                     /locus_tag="ACGI3L_003107"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HFG9198803.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            10244..11347
                     /gene="thiH"
                     /locus_tag="ACGI3L_003108"
     CDS             10244..11347
                     /gene="thiH"
                     /locus_tag="ACGI3L_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HFG9198804.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEVISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            11348..12037
                     /locus_tag="ACGI3L_003109"
     CDS             11348..12037
                     /locus_tag="ACGI3L_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFG9198805.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            12225..13619
                     /locus_tag="ACGI3L_003110"
     CDS             12225..13619
                     /locus_tag="ACGI3L_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFG9198806.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
BASE COUNT         5205 a         1684 c         2306 g         4720 t
ORIGIN      
        1 aaagactaga gtatgtatat actttatatg aatataatat tgaattaatt tatattactg
       61 gaatttttaa ttccagtaat atttttttat tatataattt agctttatta aaagttttta
      121 ttattaaaaa tagcttattt atcgtaaagt gaatgatatt gggttttaat tattatgaat
      181 gttagtattt aatttaaaga cttaaataaa tttgccattt ctagcgcatt catagcacaa
      241 tcataacctt tatttccagc ttttgtacct gctctttcaa tagcttgttc aatattttct
      301 gtagttacga ttccaaatat aacaggtaat tcactgtcta aagatacttt ggctatccct
      361 ttagagactt cactacatac ataatcataa tgagaagtag cccctcttat aacacagcct
      421 aaacagatta tagcatcata cttaccactt ttagccattt tttgagcaac aagaggaatc
      481 tcaaaagctc caggtaccca aactatttct atattttctg gagaaacgtc atgtcttaaa
      541 agacagtctt cagctcctga taaaagtttt gatgttataa attcattaaa acgagaattt
      601 attataccta tttttaaatc ttttccaata agttttcctt catatatcat ttttacttcc
      661 tccaatttta tttatgttat agatttatat ttataaatat ctttaattta attataaaaa
      721 actacttagt agaaaaatat catcatataa tcatttatat aatatctaaa agatgtccca
      781 ttttatcttt tttagttttt aaatatagct tattaaagtc attaatttct tcattaatag
      841 ggattctatt ttcgattttt attccatatt tctctaattg atttatttta tctgggttat
      901 tacttaaaag atttatactt tttatgttta aattttttaa tatttgagca gccatataga
      961 aatctctcat atcttcttca aatccaagca ttaaatttgc ttcaacagta tcgtaacctt
     1021 cttcttgaag tttataagcc ttaattttat ttaaaagacc aatacctcta ccttcttgct
     1081 tcatataaat taaaactcca cttccatttt ccacaatttt cttcatagaa gattctagct
     1141 gtaatccaca atcacatttt agagagtgga acacatctcc tgttaaacat tcagaatgaa
     1201 gtctaactag agtattttct atatttatat ttccataagt aagggcaatg tgttcttcat
     1261 ttgaataagt atctctatat cctatgattt caaaatttcc atattttgtc ggaaggaaag
     1321 cactagatac tttttctata gtagtttcat ttattttgcg gtattctata aggtctttta
     1381 tagtgatgat ttttaaatta tgcttttctt tgaaaatcat taaatcatca actcttgcca
     1441 ttgtaccatc atctttcatt atttcacaga taagaccaat ctctttaaaa cctgcaagtc
     1501 tagcaaggtc tactgaggct tctgtatgtc catccctgac aagaacccca ccagtttttg
     1561 ctattaaagg aaagatgtga ccaggcgttt tgaaatcttt acttgtagaa ttttcatcac
     1621 agaataattt tacagtttca gctctttcat atgcagatat accagttaga gtatctgctc
     1681 catctatagt aacagtaaag gctgtttgaa atgtatctgt attttctcta accataagag
     1741 gtatattaag acttttaaat tttttttcag tggcaggtag acaaattaga cctctaccat
     1801 atgtagccat aaaatttatt gattcaggag tagccatttc agctgccatc aataaatctc
     1861 cttcattctc tctactttca tcatcaacca cgattaccat tttcccattt tttatatctt
     1921 caatagcttc ttcaatagta ttaaacatgt aattcactcc tttattattt ttaaaaacca
     1981 tttttaaata aaaaatcttt atctatattt gatttatggt tattactatt agaatttaat
     2041 tccttgtagt tattagccat aaaattatta acatactttc caattacatc gctttctaaa
     2101 ttaacgaaat ctccaacatt ctttgtcaag agaatagtgt taattttagt atgaggtata
     2161 atagaaacct taaatatttc atcatctaaa tatgatatag ttaaacttac accatcaata
     2221 gcaacagaac ctttgagtat cattgaggat aaaagttttt tatcaggtcg tatacttact
     2281 aaaactgcat tttcatcttt ttcaaatttg cagatagttc ctttaccatc aacatgacct
     2341 gttactatat gaccaccaaa tcttgaagaa agactcatag ctctttcaag atttaccttg
     2401 tcatttgcat ttaataaacc taaatttgtg gaacgaattg tctccatcat aacatcggct
     2461 gtaaattcat tttttccgag gtttgaaaca gttagacaaa ctccatttac ggctatacta
     2521 tctccaagat ttgtgccatc taatatttta tttgatagta tggttacttt tccactctta
     2581 ccattagcag taatttttct aagtattcca acttcttcta ctatgccagt aaacatccta
     2641 acctcctata tgaatgtatt aacaaaaatt taatttaaaa catctgattc tataagaata
     2701 tcgccatcta tcaaagttac attattgatt gttaactgtg ttgaatctga caaatgattt
     2761 attccttctc cagaaacgaa tgtaggtgca tctttaccac ctataatctt gggtgataga
     2821 aataatttga ccttatcaac taacttattt ctaaagagac tgtcattgag agtagcacca
     2881 ccttcaacta gaacagaatc aatgtttaac tctcctaatt tatacattac aaactccaaa
     2941 tctactaagt tgttttttga aggagaaatt attgtttcaa cattattttc ttttaacata
     3001 gataatttta tactttcttt gcaacatgtg aaaactatag ttttactggt tttatcttta
     3061 accaaattac tattaagtgg caactttagg tgtgtatcta ttactattct tgtaggatga
     3121 gacacttttt cttgattgag cctacaagtt agtaaaggat tatcgttcaa aactgtattt
     3181 atgccaacca ttatactttg gtatttattt ctgtatttat gagttagata ccttgatgat
     3241 tcattagata tccattttga ttctagtgat tttgtagcaa ttttaccatc tagacttact
     3301 gctgatttta caatacaaag aggtcttttg ttttttatat gataaaaaaa tgcctcattt
     3361 aaatctcttg cttcatcttc taatattccc acagtaacat caatattgtt atcttttaat
     3421 ttttttactc cattaccaca aacaagtgga tttgggtcta atgtagatat tacaactctc
     3481 ttaatcttat tttgtataat tttatctaca caaggaggcg ttttcccata atgagaacat
     3541 ggttctaagt ttacataaag agtagagtct tttagacttt gtttagcact gtttatagca
     3601 tttacttcag catgattaga gccaaatttc tcatgatatc ctttgcctat tatattacta
     3661 gctttaacaa ttacacaccc aactaatgga tttggattta caaagccttc tccattttta
     3721 gccaattcaa tagctttttt catataataa atatcttttt ctttttgatt cacaaaattc
     3781 acaatatgta cacctcctgt ttaattggat aatttttaaa caaaaaaccc tgagaattaa
     3841 ctcagggttt agaataatct acaataaatg tttaataaat gtagaacaaa attgctctac
     3901 aaaaacactc attaaatatc ttcttccatc cagactttac tgtcggcttt ggaatttaac
     3961 caaatcaacc aagttttacc ttggctcgcg ggctataccg ccgattggga atttcaccct
     4021 accccgaaga ttaagtatta aatttatatt tagaatgtat cataaattat tttactttgc
     4081 aaactatttt tttaaaaaat atatgttaat atataatata gaatgtctat aaactttgaa
     4141 ataccacgat tgtgaatata aaaataaaaa tttgaacata atcaggaaag aagtctaatt
     4201 aatttaaatt aggagagtaa tatatgaata aaaaactttt agaaatacta tcaaaatact
     4261 atggatatac aagttttaga aaaggtcaag aatctataat aaactctatc ttaagcgaaa
     4321 aagatgtgtt agctattatg ccaacaggag ggggaaaatc aatatgttat caaattccag
     4381 ctttgatttt agatggaatg acaatagtaa tttctccact tatatcactt atgaaagacc
     4441 aagtagatgc cttaaagact atgggaatta gtgctgcttt tataaatagt tcattaagta
     4501 gcaaagaatt taatgaaata ttaaataata ttagaaaaaa taattataaa atactctata
     4561 ttgctccaga gagattagat gcacaagagt ttattgagct aataaataat aacaatgtaa
     4621 gtcaagttgc gatagatgaa gcacattgtg tatctcaatg ggggcatgat tttaggttga
     4681 gttatagaag gatttctgat tttataaaaa atttgcctaa aagacctata gttacagcat
     4741 ttactgcaac agcttcagaa gaggtaagaa ctgatataat aaatttactg tgtttagaaa
     4801 atccagatta ttatataact ggatttgata gagagaattt atcaataaat atagtaaaat
     4861 catctagtaa aaataagtat attttagatt atattcaaaa tcataaaaat gagtctggaa
     4921 ttatatatgt tgcaactaga aaggaagttg aaaatatata taatggttta tctaagagaa
     4981 atatatctgt gtcaaaatat catgcaggtt tatctaaaaa tgaaagaagt aaaaatcaag
     5041 aagattttat aaatgataat gtggatataa tggtagcaac aaatgcattt ggaatgggta
     5101 ttgataaacc taatataaga tgggttatac attacaatat gcctcaaagt atagaaaact
     5161 actatcaaga aataggtaga gctggtaggg atggagaaaa aagtgagtgt gtacttttat
     5221 tttctccagg agatgtacat atacaaaaat atttaattga tattggagtt gaaaatcctg
     5281 aaagaaaatt atttcagcat aagaagcttc aatacatgat tgacttagtt tacagtaatt
     5341 catgctatag aaagacaata ttgagttatt ttggagaaaa ttatatagac aattgcaata
     5401 attgtagcaa ttgtttagta gagggtgaaa tagtagataa aactatagat gcacaaaaag
     5461 tcatttcatg tgtagctaga atgaaaagaa gttatggtgt tactactatt gtagatgtgc
     5521 ttagaggttc taagaataaa aagattttac agcttggatt aaatactttg tctacatata
     5581 acattatgag agattattct agtgaagact taaagaattt tgtaaataca ttggtttctc
     5641 atggtttttt agatttagtt gagactctag gcaatggaaa tagaggtagt tttcctacta
     5701 taagattaaa tgagatgtct atgaaagttt taaaaggtga agtgaaagta gagtttaaag
     5761 aaattgttat gacaaaatca ttggaagtag aggatgagtt atataatgct ttaagagaac
     5821 ttagacattc aattgcaagt gaagaaagga tagctccata tatggtattt ggagatggta
     5881 cacttagagc catgtctagt agttatccaa ttaataaaga agaaatgcta gatatctctg
     5941 gagtaggaga aattaaatat caaaaatatg gtagagattt tgaagcagta attaaagaat
     6001 atgtcgaaaa aaataatata aataaaaaaa tagatgaaaa aaatgtcgat tcaaagaacg
     6061 ttaatagtga tttcttagag gttaatacag ataaagtttt atatgaaaaa ctgttagtca
     6121 ttagagaaga atatgcaaca aaggaaaaat tacctgcata tatgatttta gccaataagg
     6181 ctttgaaaga aataagtgga agatatccac ttgatgaaga acaattaaaa gatatttctg
     6241 gcataggtgg agtaaaattt gaaaaatatg gagctagtat tttggcagag gttaataaat
     6301 atgtaaaaga aaataatatt aatgttattt gggagaaaaa gggcaaaagg aagttaatat
     6361 tagatggaga aagtagaaaa aataatgaaa tagcattaga tttgctaaat caaggaaaag
     6421 atatacaaag tatcagtcaa gaaatagaag tttcactgtc aaccattatt ggatatgtgc
     6481 atgactatgt aaaggatgga catagtatat catttgaatt aggactagaa aatttttata
     6541 atgaagataa aaagaagatg attttagaag tttgcgaaaa agttggctat gataatttaa
     6601 ataacataaa aagaaaactt ccagattcaa taaagtatga aaatataaga gctgtgatac
     6661 ttgactctta tcttgaaaac ttaaaaaata atattatagc agagtaattt ttaacttaat
     6721 aaaaaataaa atttgtatta ttgtgttgaa ctaataattt tgctgtgtta tactgaattt
     6781 gtaaaaataa tgaaaaatta gagctagggg cgctagaatt ggctagctga gagataaagc
     6841 cgtaacttac aaaccctaat aacctgatca agataatgct tgcgaaggga agctttttaa
     6901 tataatttta ttatataaat aggcaaatta ttcaatgtta ggagaaattt gtctaagtgt
     6961 atatacgatt ataagagtgc tttccaaacg aggaaaagca ctttttttat tttcaaaaac
     7021 tataacttta atcttggagg attgtaatat gaactataca acacaaatgg atgctgctag
     7081 aaaaggcata ataactaaag aaatggaaat cgtttctcaa aaagaacagg tagatgtaaa
     7141 tgaattaaga gaattaatag caaatggaca agttgttata ccagctaata aaaatcataa
     7201 atctttaagt gcagaaggtg taggtaaaaa tttaagaaca aaaataaatg taaatctagg
     7261 aatttcaaga gattgtaagg atatagaaaa agaacttgaa aaagttagag tagcaataga
     7321 catgaaagct gaagctataa tggatttaag taattatggc aaaactagag aatttagaga
     7381 aaaggttgtt gaaatgtcac ctgcaatgat aggttcagta cctatgtatg atgcagtagg
     7441 atatttggaa aaagaattaa aagatataac agaagaagag tttttaaatg taataagaca
     7501 acatgctatt gatggagtag actttattac tatacatgca ggtcttacaa gaagtgtttg
     7561 ccaaaaaata aaaaatcatg agagattgac tcatatagta tctcgtggag gttctttatt
     7621 gtttgcatgg atggaattaa ataataagga aaatcctatt tatactaatt ttgataaaat
     7681 attggatata tgtgaagaat atgatgttac attgagttta ggagatgctt gtagaccagg
     7741 ttgtataaaa gattctactg atggtgttca aattcaagaa cttgtagtat taggtgaact
     7801 tactaaaaga gcatgggaaa gaaatgtaca agtaatgata gaaggtcctg gacacatggc
     7861 tattgatgaa atagaagcaa atgtagtatt agaaaagaga ttatgccatg gagcaccttt
     7921 ttatgttctt ggaccattgg ttacagatat agcaccaggt tatgaccata taacaagtgc
     7981 aataggagga gctttagcat gtgccaaagg agtagatttt ttatgttatg taactccagc
     8041 agaacattta agattgccta atttagatga tatgaaagag ggtataatag ctgcaaagat
     8101 agctgctcat gcaggagata tagctaaaaa tgttaaaggt gctcgtgaat gggataataa
     8161 gatgagtaaa gctagagctg atttagactg gtgtgagatg tttagacttg caatagaccc
     8221 tgaaaaagct aagagataca gagatgaatc aactcctact catgaggata gttgtactat
     8281 gtgtggaaaa atgtgctcaa tgagaacagt taagaaaata ttaaacaatg aggaacttaa
     8341 tctaatataa tttttggcta gtatgactgg aataaaaata agctgaaaag aggaggtgat
     8401 ttagtgaagg ttaatgggaa ggaaattgaa tttgaaaaag atttgactgt tatagattta
     8461 ttaaataaat ataatttaaa aagtgataga gttgtagttg aagtgaattt agagataatt
     8521 gaagaatcta actacaatac atatgtatta aaagacgagg acattgtaga gcttattagc
     8581 tttattggag gtggttaaaa taaaaatatt tgtaaatgaa ttattaacag atgttgagga
     8641 aaatacaact gcttataaag ttagagatag ctataacaat aaatgtgatg tattggtgtt
     8701 aaatggatat ccaattaaaa cagatatgac cctttgtgaa aatgataaat taacacttat
     8761 acaaaaagga gttaagccat cacttgatga attggaaagc ttgttgattg ctagacatac
     8821 tccaaatata cataataaat taaaaaaagg gaaagttgct atattgggat tggggggact
     8881 tggttccaat atagctatct ctttagctag aataggagtg ggagaacttt tacttataga
     8941 ttatgatgtt gtagaaccat ctaatttaaa tagacagcag tattttatag atgatatagg
     9001 aaaactaaaa actgatgcca tgatagaaaa tataaaaaaa ataaatccat ttataaaatt
     9061 aaataaacga gatatttttt taaacaagaa caatatggat actattaagg attcagattt
     9121 aataattgag gcctttgatg atgcttcatg taaagcacag gtatgtaatt atgtattaat
     9181 aaatttaaaa gataaatatt taatagcatc atctggtatg gcaggttact atgattcaaa
     9241 tataataact actaagaaga taaaagacag gttttatata tgtggggatt ttgtgaatga
     9301 agctaaattt ggtgaagggc ttatggctcc aagggttgcc atctgcgcaa atcatatggc
     9361 aaatttggca acgcaaatac ttatagatat gtaaatatta aaattagata taaaaaagat
     9421 tgaatattaa aaaaatttaa cgtggaggga aataatatgg ataaattggt acttggtgga
     9481 catgaattta atagcagatt attggttgga acaggtaaat atggttcaaa taatatattg
     9541 cctgaggtaa taaaagaaag tggaagtgaa ataataacaa tggcacttag aagagtggat
     9601 ttagacaata aacaagaaaa catattaacg tatattccaa aagagatgac aatacttcca
     9661 aatacatcag gagctactaa tgcagaagaa gctgtaagaa tagctagaat atctagaaaa
     9721 atgggatgtg gagattttat aaaaatagaa gtaatatcag atactagata tttacttcct
     9781 gataatgaag aaactataaa agctacaaag atacttgctg atgaggggtt tatagttctt
     9841 ccatatatga caccagacct ttatgctgga agaagactta tagaagctaa tgcagcggca
     9901 gttatgccac ttggagctcc aattggttca aatagaggtc ttcaaatgaa agaaatgata
     9961 agaataatga tagatgagtt ggatatacca ataatagtag atgcaggtat tggaaaacca
    10021 tctcaagcta tggaggctat ggaaatggga gctgatgcag tacttgtcaa cactgctata
    10081 gcttcagcag gagaccctgt acaaatggct agagcattta aattagctgt agaaggtgga
    10141 agagaagcat atattgcaaa aacaggaaat gtgtcagaat ttgcaaatgc atcttctcct
    10201 ttaacaggtt ttttaggcaa tttatagaaa gtggtgattg gtgatgagtt tttatgatgt
    10261 aatagaaaaa tatagggatt ttgattttga tggatattta aataatgtta ctgataatga
    10321 tgttttaaga agtttatcaa aagacaagct tgaagatttt gatatattaa atttgctttc
    10381 taaaactgca gtaaaacatt tagaagatat ggcacaaaaa gcacataaat taagtgttca
    10441 atactttggt aaaacagtat gtttatatac accaatgtat atagcaaatt attgtgttaa
    10501 tcaatgtgtt tattgtagct ataatataaa gagtggaata aaaagaaaaa aattaactat
    10561 ggatgaaatt agagaagagg gagaagtaat ttcaaaagaa ggtttcaaac atctacttgt
    10621 tttgactgga gaaagtagtt ttcactcaag tgtagaatat ataggtgagg ctatagaaat
    10681 attaagagag aaatttccct ctataggtat agaagtttat ccaatggaag tagaagaata
    10741 taagtacatt gtagataaag gtgttgaagg attaacagta tatcaagaaa cttatgacga
    10801 ggaaatatat aagagagtac atataaaagg cccaaaatca aattataaat ttagactaga
    10861 tgctcctgaa agaggggcaa aagcaggtat gaggacttta tcaataggtg cacttttagg
    10921 gctaaatgat tttagaaaag aaactttttt tacaatattg catgggaaat acttaaaaac
    10981 gaaatatcct catattgagc tttcatattc aacaccaaga atgagacctt ttaaagggtg
    11041 ttttgaggaa ttggtagata taagtgatac tgatttagtt caagctatgg tatgtatgag
    11101 attatttgac cctcatgcag ctataaatat atccactaga gaaaatttag aaatgagaag
    11161 tcatataata cctttaggag taactaaatt gagtgcaggt gtatctactg atgtaggagg
    11221 tcattctcaa gatgaacatg atactgctca atttaagata aatgatgaaa gtactgttaa
    11281 agatgtggag aaaatgctaa actcaattgg ttatcagcat gtgtttaaag attgggaaag
    11341 attttaaatg tatctgataa caaacagaaa attatgtagt gaggaacgat atttagaagt
    11401 tattaaagag tctatattga gtggtgtaga aaatataata ataagagaaa aggatttaga
    11461 atatcaagag ctaagaaaat tatatatgaa aataaaaact aaaatcaatt gtatagattt
    11521 tcaagagcaa atatcagatg aaagtttgaa aactaatata aatcaaaaag agtttagaaa
    11581 taaattcaag gttaatttta taataaatag taacattgaa ttttttgaaa aagtggattg
    11641 tcaaggtatc catcttcctt ttaaattatt cttgaattta attgaaaata agtataattt
    11701 taatgaaaat aaaatactag gattatcttt acataaagta gaggaagtag attatttaga
    11761 aaaattaata agaaatcaaa atataaaaat agattacata acattatcac atatatatga
    11821 aactaaatgt aaagaaggat taaatccaaa aggaattgag cttttaaaag aagctaaaaa
    11881 gattactgat attaaaataa ttgcacttgg gggaatttta ccatctaatg tcaaggaaac
    11941 attaaaatac tgtgatgatt ttgctataat gtcaactata atgaggtcta aagatattaa
    12001 aaaaaccata tcaaattata atgaaaagtt gaattagtaa atatagtata ttgaattttt
    12061 aacttaaata aaaataaaaa agttatcttt taaattttaa aaggtagctt ttttatttta
    12121 tatctttgct aataaaaaat tgtaaaaagg gaaaacttta gtcagagaga ttaaacaata
    12181 tcctagaaag atttaaaatt tagtaaagta tggaggacat tataatgact gacagtaaaa
    12241 agaaacgatt tattatacca cacactttta caataatatt tttactaata gtcttgatgg
    12301 caatattgac ttggatagta ccaagtggtg aatttagtag agaagatgta gaaggtagaa
    12361 tggtagttgt accagggact tatcaaagtg tagaaagtaa tcctcaagga tttgcagatg
    12421 tttttaaagc accaatagaa ggctttatcg attcagctga agttgtaggt tttgttttaa
    12481 tagttggagg tgcttttggt attgtaaata ggactggagc tatagaagca ggaatagctt
    12541 cggttatctc taagtttaag ggaaaagaac ttcttataat tccaatatca atgattttat
    12601 ttggacttgg aggtacaaca tttgggatgg cagaagagac attaccattt tatatgatat
    12661 ttgttccact catgacatcc ttgggatatg attctctaac agcaatagca attgtattta
    12721 taggagcagc agcaggagca gccgcttcaa caataaatcc attttcagtt ggtattgcac
    12781 aggcactagc tcaacttgct cctggttcag gagtaactta cagagtagtt atttttatag
    12841 catatatact aataagtata gcatttgtta tgtactatgc taagaaggta aaggaaaatc
    12901 ctgaaagttc aatagtatat gaaatagata aaaataataa atcaatactt aatcaaactt
    12961 caacagaaat aaaagaattt acttttaaag aagtatctgt tcttgctata tttggaatag
    13021 ggatggcaat aatgatttgg ggtgttttaa gtcaaggatg gtacattcca gaaatatcaa
    13081 tgtgttttgc tgcaataggt gtgctttctg gattggttgg tagattatct caaattgaaa
    13141 tctcagaaag ttttatagat ggagcaaaag atttagcatc tgcagctctt gctatagctt
    13201 tggctcgtgg aatcgtaata attgctcaaa atggatttat aatagatact atattaaatt
    13261 ccgcagcagc ctttctaggt gggcttccaa aggttatatt tgtatattta tcatttttct
    13321 tggaagctgc attggcattt ttaattccat catcttcagg tcttgcttca cttacagtac
    13381 ctgtacttgc tcctcttggt gatttggtta atatatcggc tcaagtgata gtaaccgctt
    13441 atcaatttgg tgtgggtctt acaaacttta taactccaac ttcaggagta ctgatgggag
    13501 cacttgcagt agcccatatt ccattttcaa aatgggtaag atttataatg cctatcttgt
    13561 tgattttgac agctgtatct ctagtctttt taacaatagg tatttatata gggttttaat
    13621 taagtgtagt tttatttaag atatttagta atggtataaa atgataatat gttttcaata
    13681 aattgccact aatttaatta gtggtaattt gttttttgta tttaaaaata aatgtattta
    13741 cttgtatttt gaattaatat ctacttagac attgttttaa ttgttatatt tttatttaat
    13801 taagcattga tttatcattt tttatatttc atataacaat gcaaaaaata atttttatat
    13861 agtaaatgac aaaagtttac aataaatgta tattttctta ctcattcctt aaaat
//
LOCUS       DAYAKB010000087        13810 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.087, whole genome shotgun sequence.
ACCESSION   DAYAKB010000087 DAYAKB010000000
VERSION     DAYAKB010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13810
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.087"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(80..2299)
                     /locus_tag="ACGI3L_003111"
     CDS             complement(80..2299)
                     /locus_tag="ACGI3L_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9198807.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(2575..5229)
                     /gene="adhE"
                     /locus_tag="ACGI3L_003112"
                     /gene_synonym="adhC"
     CDS             complement(2575..5229)
                     /gene="adhE"
                     /locus_tag="ACGI3L_003112"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFG9198808.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            5733..5933
                     /locus_tag="ACGI3L_003113"
     CDS             5733..5933
                     /locus_tag="ACGI3L_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198809.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(6140..6730)
                     /locus_tag="ACGI3L_003114"
     CDS             complement(6140..6730)
                     /locus_tag="ACGI3L_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HFG9198810.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(6733..7608)
                     /gene="dpsA"
                     /locus_tag="ACGI3L_003115"
     CDS             complement(6733..7608)
                     /gene="dpsA"
                     /locus_tag="ACGI3L_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HFG9198811.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(7684..9075)
                     /locus_tag="ACGI3L_003116"
     CDS             complement(7684..9075)
                     /locus_tag="ACGI3L_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFG9198812.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(9079..10215)
                     /locus_tag="ACGI3L_003117"
     CDS             complement(9079..10215)
                     /locus_tag="ACGI3L_003117"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HFG9198813.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(10247..10792)
                     /locus_tag="ACGI3L_003118"
     CDS             complement(10247..10792)
                     /locus_tag="ACGI3L_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFG9198814.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            11116..11886
                     /locus_tag="ACGI3L_003119"
     CDS             11116..11886
                     /locus_tag="ACGI3L_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198815.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLSL
                     NKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTFYCCGNCDSEISLSQREHFKI"
     gene            complement(12340..12768)
                     /locus_tag="ACGI3L_003120"
     CDS             complement(12340..12768)
                     /locus_tag="ACGI3L_003120"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFG9198816.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKNFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(12964..13197)
                     /locus_tag="ACGI3L_003121"
     CDS             complement(12964..13197)
                     /locus_tag="ACGI3L_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFG9198817.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSIFISTKW"
     gene            complement(13477..>13810)
                     /locus_tag="ACGI3L_003122"
     CDS             complement(13477..>13810)
                     /locus_tag="ACGI3L_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198818.1"
                     /translation="VTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKASTIEIG
                     IVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFFIVRNNYLKE
                     IRLNLVNF"
BASE COUNT         4704 a         2222 c         1500 g         5384 t
ORIGIN      
        1 aaaaacacta attatttagc aatgatttat taaaatcaag cattcataat agtgctttat
       61 ataaaaatca aattttgttt taaagtaaat ctaaaaaatt cttagctggc attggtcgtg
      121 caaaataaaa tccttgaact aaatcacatc caaattgttt cattaactca gcttgttctt
      181 tactctcaac accttctata attacaacta aatctagtga ttttgctaga gacactattg
      241 attttgctat attgcgactt ctctcatcat gttcaatgcc accaagaaaa gacttatcta
      301 gcttcaatat atcaattggc atatctctta aacaactaat agaagaatat cctgtaccaa
      361 agtcatccat agaaatagaa aatccatacg tcctcaactc atttaaaaca ttctttaaaa
      421 tatttaactc attaatagcc acagtttctg ttatctctat ttcaatgaaa tctgaactta
      481 aattatacat ttttattgtt ttattgataa attttacaat atctggttga tacaactcga
      541 ccctagataa atttactgaa actggaacta tctttttacc ttgctttttc cattcatata
      601 aatcattgca aaccctttca aatacaaatc tcccaatttt taaaatcaac ttacttttct
      661 ctgctattgg aataaatact gcgggactta taaaaccatg ttctggatga ttccatctta
      721 ttagtgcttc actccctatc atttctccag ttacaagtga aaacttaggt tgataataca
      781 cttcaaattg attttttacc aatgctattt ttatatcatc taaaatcatt gattcctcac
      841 taagcttatt cctaacatct tcattataaa tagcataatt tatattttta cctttagcaa
      901 cagacctagc catatttgct ttatttacag ccttttgaat atctacttca ccttcttcaa
      961 caaaataaat acccacacac agagaaattt caaagactat actcaaatta ctttcaatat
     1021 tacttcgtat attatcaagt tttcttataa ttttatttct tccattttta taatcacaga
     1081 aaattgcaaa ataatcactt gaaagtcgtg catatacctc accttctgtt aattcttctt
     1141 ttaaagcttt tgctattgta attaataaat tgtcaccaaa ttcatatcca aaagtatcat
     1201 taatcatctt aaagttatta atatcaaaat atactataat ataatttaaa gatggtttat
     1261 ctaaaagata cttactacat tctctataaa atttattttg atttcctata tatgtaactt
     1321 tatcttcata agccaaactt aatatttctt tttcattaga tttttttata taaattatat
     1381 aaaaaataat tgcaataaat attaatacaa tagataacac tgcatataca gctctgttga
     1441 ttatttgttt tgaattacta aatacaacag tttctggaat tgaaaaaatt aaattccagt
     1501 cttttatata attattttca ctattcccat tatccatagt ggcatatcct aaatatcttc
     1561 tttcttccaa catatttaat acagttgcac ctgttttatt ttcttgcaat tcttttttta
     1621 atctatttac ttcttgaata tcattatcct gttttaacaa tttataaata ttttttgata
     1681 ggctatcccc ttgtggatga aggataattg taccattatt ttttacaaca taagatatac
     1741 tattattttc ataaaaagat atattaataa gtttcatcag agtattgata ttgtaagtac
     1801 aatataaaac tccaactact ttatcattat ttaataatgg tactgaaata gcaatcttct
     1861 ttatagactt atttacttca tcaacatatg gacttgaaac atacttctta cctttaattg
     1921 agtttttgaa aaattctcta tctttcactg aaaacttatc acctttggta ttttcagcat
     1981 taccatttat atcaactatt gccatagtgt aaaatttttg attttccatt tcatctaaaa
     2041 gatttttcat tttttcctca ttaggtatat ctggatttga agcataatag ttagaaaaaa
     2101 tatttaaaac atctaaatct ttttcaattt gtctttgtgc tagttgagag ccttgtactg
     2161 caacttcttt tatatgtatt tttgcctctg acataagaag atgttttgta tcttctatat
     2221 agatataccc cattgtcaaa aataatgatg ttaaaaaaag aattgtaatt aatgtaaaac
     2281 ttttatttct ccctgtcatt cgactcctcc cctaattagt caatacttca tatagataat
     2341 atatcctttt tataccaatt catcatttat attgtatata actattctta aatgttacac
     2401 ataaaatcaa cataataacc ataaaaacat tcttttatta ttataataac actatttaat
     2461 tgaattttaa attaaagaat aaaaactatc cattttctca aacaaaaaaa ctcttataca
     2521 ataaaacttt gttttatgta taagagtttt tattttatct attttatagc aaacttatct
     2581 tccataatat gaatttaaat acatatcttt tatttcattc ataagtggat atcttggatt
     2641 tgctcctgta cattggtcat caaatgcttg aattaccatt tcatctattg aatccataaa
     2701 cttagattct tcaacgccaa actcttttat agatttagga ataccaactt taagttttaa
     2761 atcttcaata gctaccaata aactttggaa tttctcttca tcagaatttc cttttaatcc
     2821 taaaaatgaa gctatttcag catatctctt taatgcttct ggatatttat attgagagaa
     2881 tgctcccatt ttctttggtg catctgaaga attaaatttc ataacttctg ttatcaaaag
     2941 agcatttgca acaccatgtg gtacatggtg gaaagcacct aatttatgag ccatagagtg
     3001 acaaacaccc aaaaatgcat ttgcaaaagc catacctgcc attgtagaag catttgccat
     3061 tttttctcta gcttctgggt cttttgcacc attatcatat gcacgtggaa gatattcaaa
     3121 tatactctta atagcttgta aagctaatcc atttgtataa tcggttgcaa gcatagatac
     3181 atatgcttct aatgcatgag ttaaagcatc tataccagaa gcagatgtta agctttttgg
     3241 catattcatc atcatatcag aatcaactat agccatattt ggcatcagtt cataatctgc
     3301 taatggatat tttactcctg tatcttggtc agttataaca gcaaatggtg ttacttctga
     3361 accagtacct gctgatgttg gtatagctac aaaattagct ttttcaccca ttttagggaa
     3421 tgtatatacc ctttttctta tatccataaa tctcatagct aggtcttgga aatctacatc
     3481 tggatgctca tacaatgtcc acattatctt tcctgcatcc attgcacttc ctccacctat
     3541 agatattatt acatctggat taaattctct catagcttta gcgcctatct tagcacattc
     3601 caaagttggg tctggttcta cttcaaagaa tgtagtgtac ttaatattca tttcatctaa
     3661 taaatcagta actgctttag tatatccatt attgtaaagg aatgtatctg ttacaataaa
     3721 agctctcttc ttattcatta catctttaag ttcttttaat gctactccta aacaaccttt
     3781 tttgaaataa actttttctg gtgctctaaa ccaaagcata ttttctctcc tctcagctac
     3841 tgttttaata ttaagtaaat gcttaactcc tacattttca gatactgaat ttccacccca
     3901 agacccacat cctaaagtaa gagaaggagc tagtttaaaa ttatataagt cccctatacc
     3961 accttgagaa gaaggagtat taattaaaat tctacaagtt ttcatggctg aagtaaactt
     4021 atcaagtttt tctctttgat ttacatcatc aatatataat gaagatgtat gcccaaatcc
     4081 accatcttct actaattttt ctgcttttct aactgcatca tcaaaatcac ttgccttgta
     4141 cattgcaagt actggtgaaa gtttctcatg agcaaaagct tcttctattt caactgattc
     4201 tacttcacct attaaaacct tagtatctac tgggacttca aagcctgcaa gttttgctat
     4261 agtacaagct gtttgcccaa ctattttaga atttaatcct ccatttacta aaattatatt
     4321 tcttattttt tctgtttcat ctttatctaa taaataagca ccacgctctt taaattcttt
     4381 tttgacttca ttgtatatat tttctaatac tataaccgat tgttcagaag cacatatcat
     4441 accattgtca aaagtcttag atacaagaat tgagtttaca gcagttttta tatctgcact
     4501 atcatcaatt attgctggag tattacctgc accaactcca atagctggtt ttccagatga
     4561 atatgctgat ttaaccattc caggacctcc tgtagcaagg gtcaaatcca cttctttcat
     4621 aacagttgta gttaattcta aagatggctc atctatccat cctattatac cttcaggagc
     4681 tccagctaaa acagcagcct caagaacaac ttttgcagcc tctatagtag aattttttgc
     4741 tcttggatgt ggagagaaaa ttattccatt tctagttttt aaagctaaaa gtgctttaaa
     4801 gatagcagta gaagttggat tagttgtagg tacaactgct gcaataacac ctattggttc
     4861 agcaatttta gtcataccaa atgcttcgtc tttctctata acaccacaag ttttagtttc
     4921 tttatatgca ttatatatat actctgaggc ataatgattc tttataacct tatcttcagc
     4981 aattcccata ccagtttctt tttgtgccat tatagctaga ggaactcttt gcttattagc
     5041 tgccaaagat gctgctaaaa aaattttatc tacctgctct tgactatatg tagcaaatat
     5101 tttttgagct tctctgattt ttgctagttt tttaactaag ctttcaacgt tatttacagt
     5161 atctaaacca actgacataa cttcattttc ttttttattt tctattatta cttgttcttt
     5221 atgagccatt ttaacaacct cctgagatag ttttttattt attatgttaa tttattaaca
     5281 ttatagcatt tacttttcct attttcaagt tattttttta acattttatt ttttatctaa
     5341 tataacatca tttctactaa taatatctag ctttacaaat acttaattta actagatatc
     5401 actttatttt ttacgcaaat cactaatgaa atcatctaaa aacttaagga taacgttatt
     5461 tttttaacgt ttatattttt gtattttttg caaataaaac tttataaaaa gaatttttaa
     5521 tatgatactc tatcaagttt aaaaataaaa atccttgaaa atgaaaatta aaacttaatt
     5581 aacaagttaa agtaaatata gttaaatgta caaacattta caacatatag tataattaaa
     5641 aaaatatata ttcatgattt ttatataata tgaaataaaa tatatttaat attatataga
     5701 taaatttgaa gtttataaga aggaggataa gcatggaaaa attaaaaaca attagcgttt
     5761 tttctttgat tataagtgta attttaacga ttggaggtat tggaatagta acttattatg
     5821 tagataattt gtttattaga ggactatcag tatttgtttt aattatgtcc tcttcttttg
     5881 tatcaacaac agttagattg atatttgaag agtcaaaacg atataaattc taatttaaaa
     5941 attggattaa gtaaataatt ttaatatagc aaaaattacg gagattagct caaaatagac
     6001 tttttagtcc atgaggcatt tttttgtatg aaattaaata tattttcatc atttcaacaa
     6061 gaaaaagagg cttctctcta ttttgagaca gcctctttgc tagtattgta tctaatacat
     6121 aatattataa gaaccaattc tattgatgtg gactttttat aacaggctgt agctgtttgt
     6181 tctctagagc aagttctata gttggaatta ttagctcagt atgtgcaatc atagaattag
     6241 gctttgcttt gcaattatct tgaccaaaag gtacaaaata tatattttta gaattaagga
     6301 gaatgccaat atttttgaaa ttaaagctta gagcatcatt cgttgatatt gatattacta
     6361 gtggtttatc attacgaaga tgaccttttg ctgccattaa tactggtgaa tctgtaatac
     6421 catttgctaa ttttgcagca gtatttccag tacaaggagc tattattata atatcagcaa
     6481 ttcctttagg tccaaatggc tctgcctctt caatcgtaac tataggttta tttcctgtaa
     6541 gttcatatgc ttttttcata aactcttcag aatttccaaa tctacaatcg atattttgtg
     6601 atacatctga aaatatagtg tgtacattag ctccttcttt aaccaaattc tctaactcta
     6661 taaatatttt atcataagta caaaacgaac cagtaaatcc tactccaatt gtaagtcctt
     6721 caagtctcat ttctaatccc ttctttcatt tataatattt tctatagcgt taacaagaat
     6781 ttcaccagat gtctttggtg aatatttacc aggaagccca aggcaaagag tcgcattaat
     6841 ccctgcttct ttaacaacag aataatctac tcctccagga gaagaagcta tatctataat
     6901 agttacttct tgtgatactt tttctaacct ttctttcgtt aaaatacact ctggtatggt
     6961 gttaaaaata taatcaaatt gtaaaagttt ttcatcaagt tgacttaaag aaatactgga
     7021 atatccaaat gcattagccg tacttcttgc atcattattt cttgcgccaa cacatacatt
     7081 tgcatccaaa gcgtataatt tttttgcaag tatttgtgca catcttccat aacctaatac
     7141 taaacagtta ctttgatgta tattgattat acttctttta atagcttctg ctatagcccc
     7201 ttcagctgta gcaactgcat ttaaaatagc aacatcattc attttcataa aatcataaat
     7261 ctgaatagag tgttgctcgc aaaatttaca aactttagtt ggtatgttac ctccaaataa
     7321 tatttgatta ggagataaat taattagcaa gttatcaata gtagcatcaa gacaatcatc
     7381 cgtattttca atattaactt gattctttgt aaatggaatt ggacataaaa taatggaact
     7441 tttggatagt gcttcagcta gtgaagttga ttttccaacg attccattta taatttcatt
     7501 tgatatccca taagtgacta cagaataccc tttattaatt agttttttta ccatgtacac
     7561 ttgtcgcagg tctcccccaa taacagttat atcgtattga tttgacatat tgtaagcctc
     7621 ctttactata tacaatatgt ttttatcaat acattggttc actaaaatta ctaaatatta
     7681 tacttataac atttttaata atgctaatct atctatcttt tcagaagagg tatatggaaa
     7741 tgaatttaaa aagataattt tctttgggat ttcatttttc attagattat ctttcatttt
     7801 aatcaacaaa tctttcttcg taattttgtc tatagttatt acaaataata caatttgatt
     7861 tcctcttata gtgtctgagt acggcaatac aattgcatct tcaatttgag gaattttttt
     7921 aacttcattt tcaatcttag tagaactaac tttaaatcct ccaatattta taatgtcatc
     7981 acttcttcct tcaaatatta agtatccatc attatcataa tatccaatat cattgacaga
     8041 ataaggtttg gttgcattat atactgcata ttctgtattc acaaaaattt ttccttctct
     8101 aatatatata tctattcctg gaaatggtct gcctacactt agaggttttt caattagttc
     8161 atcatagcat aaatatgtaa tataatttaa ttcacttgcc ccatagtata aaataatttc
     8221 agactttggc atatattttt ttagatttct tgcagtatct tcaaataata attgagaccc
     8281 tgtaaaaata cttacaactt tgagtactgg ttcttttaag tgtttaacca aaagttgaag
     8341 ttttgtaggt ataaggtata tgttagttac attatattgt tttattgtcc ttatccatga
     8401 tttacaatta agacctgaac ttattacaat actacctcct tcatataata ctgacattat
     8461 agaatttaga ttccctgtaa aactaagtgt tccattaaca aacaagattg attccccaga
     8521 gatattaaaa ataccatttt gtataggaaa aaatccagcc caactctcat atgttctata
     8581 taataccttt ggaacacttg tagaacctga agataaagct cccatacaaa tacttttatc
     8641 taaataattt ataagcttct tatattgata catatatata ttaaatttag gattaaaaat
     8701 agaaaaatta actttttttg ctacttcatt attgttatca tcatataaat caataacgtc
     8761 catagattca tcagatataa tgattgaaat attatttttt aataaaatat catctaatac
     8821 ttttttagaa agattataat gacaaataat aggaatattt tttgaataat taatagcaaa
     8881 aaaactaatc aactgaaaca ttatattttt agaatatatt aaaattggga tattttcacc
     8941 taaagaaatt tgctttccta gttcctcact ataactcaat atattttcat aagtatattt
     9001 ttctccatct ataattaaaa aatttttatt tttatgcctc tcttttttta ttcttaaaag
     9061 ttcataatag ttcataatct acaccctttc aagcagtaaa gctgaaccta gaccaccagc
     9121 tgcagctata gagcaaattc catatctacc cttagtcttt tctaatgctt ttaaaagatg
     9181 taatgcaata attgcacctg aagcaccata tggatgtcca tacgctaaag ctccaccaaa
     9241 tatattatat ctatctatta actctggata ctttctttga aacaacacat ctataactgc
     9301 aaatgcttca ttaaattcaa cagcagatac atctaaataa ttaaggcttt ctatctctaa
     9361 aagtttatcc attgcttgta tcgctgatgt tggacttaag gttgcatctg ttcctatcgt
     9421 gcatgtgtta ataatttttg ctttaggctt cttttttaca tgttctaaat acttcttaga
     9481 acatattata ataaatgaag ctccatcatt aataagacat gaatttgctg catttgtaat
     9541 agtttctttt cctaaaattg atggcatcct atctaataac ctttgactca tcttatcacg
     9601 tataccttca tcataggtac tattatttat aggagatata atatcttcaa gtattttttc
     9661 ctctcttgct tcttttgctc ttttatgact ttcctttacc caaaaatcca agtctgcttt
     9721 ctcaatttga tataactctg ctactctttc cgcaccttcg agcatactat tttggctatt
     9781 atcatcagga gaaaattgag caactgtata atttggatta tttgtattat atcgcttatc
     9841 attcttatga tatgtgcgca ttggttgcag agaactactt tcaaaaccac ctgcaataat
     9901 taaatcacac tgaccagatt taacctttga aaaagctatg tctatactca tcatagcaga
     9961 agcacactgc atatccacag taaaagcagg tacttcattt gacactcctg ctgttaaagt
    10021 cattaatcta gctatattcc ctcctgtccc aactgcattt ccacatataa tctcatcaat
    10081 tttgtcaatt tcatactttt taattaaatc ttttaaaaca cttgctccta gtaattcagg
    10141 ttgaacaaat tgaaaaattc cattttttag acctatatga cttctcaatc ctcctaatat
    10201 aaaaacttcc ttcatacatt acacccttcc ttatattata gatttatcat agatttcttc
    10261 tgagtacatt gttcagttta gtgcctaaaa aagatgcaat aactgacttt attgtatctc
    10321 caattaaaaa tggtactact gctgcaaaaa gtgctgcttc tactgtcatt tgattaaaat
    10381 agcacataaa tactgttccc ataaaatata taataggcat tccaacaaaa attgttatta
    10441 atatatatct cttaatatca ttatttcgtc cttttaataa actaataatt agtgctgcaa
    10501 acaaaaaccc aaaataaaaa ccacctgttg ggcttaataa ctttccaata ccagatgtac
    10561 ctccaccaaa tactggaatc ccaattaaac ctatcattat atatacacca actgtactaa
    10621 atgcttgtct tggtgttaaa atcaaagcta ttaaatttat cattattgtt tgtgctgtta
    10681 ctcctgctgg agtaaatggc aatggtatat atatgtaaga tgatatacac aataatgcta
    10741 cacatattga cattttagtt aaatcttgaa tatttacttt agtatttttc atttttataa
    10801 ttcccttcat atgtcttatt tcatttagtt tatatgtaca tatacaaagc ttctattaaa
    10861 gctttgtttt agtataaaat aaagacgttt ttttgtcaac tattataatt atttaggttt
    10921 acatttaatt tataagtaaa ctttatactg ttactttata ttttaatagt catttataaa
    10981 actttgctta aaaacagctc tatttagact atacttgtaa attataatat gatatatttt
    11041 tatataagat tttattttat ataaaaaata gtaacaaata gtttatacac aagatattta
    11101 aaaggaagtg atgatatgaa agttaatgaa aataatatag atgaagagtt agatgaactt
    11161 agtaggaaag tttacttaga gtcaccagat ttttggataa gtatttctga caaaataata
    11221 gataaagtat ttgatgaaat gttattattt tttgcagtta aatataacta tttcaatata
    11281 gtatgctttg ctattgaaaa caattatctg gatttaaaca tgccttcaaa aaacaaaaaa
    11341 tacactaata taatggagca tttgttagat acatcaaaac agaatgaaga taaaaaaatt
    11401 tataattatc ttctaagctt aaataaaggt aataacctag atgaaagacc aattttagat
    11461 gaattaaact gtaatattag tagtgatact tttgaaaaaa aagatatata tcttccaaag
    11521 tacttatgtc caagttgtaa ttctaatata tttgatacag gttataaagt atcaaatgac
    11581 ataacatata aattttcttc taaagaagct gaacctattg aaatgtgtag tgaagtttct
    11641 tctatcagat gttgtaattg tgatgaatta ttagaagata ttacacttga taaactatat
    11701 aacctatgca aaattcaaaa ctgtaataat tgtggttcta atttaactaa ggtaggaatt
    11761 attgcaaaga aaaaaatgaa ctttgatgag aatactgaaa aatttaaaga tgtctcaaca
    11821 ttttactgtt gtggaaattg tgactctgaa ataagcttat ctcaaagaga acattttaag
    11881 atttaaatat ttataggcta aagtaataag attacattat tagatactgt ataagttttt
    11941 taaatctgta aaaataaata cacttataag aattaaaatt gctatgaaac tagttcttga
    12001 tgaactaatt tcatggcaat tttctataat ctaataatta ttaaatttta acaaaccttt
    12061 attagcattc cataattatt taaaattctt tcaatactct atagtttata ggtgaaagta
    12121 tctttaatat tatatcaaac ttattatctt taaatagtaa atttgttaaa tctgaaatac
    12181 accatacaat tttattttcc tcttttgtag ctatatcaat tctgattaac ttacatctat
    12241 aataaatatc tttatcttca tatagtctat tttaaaaatt actcttaaaa aatcaactag
    12301 aaaataaatt aattatcctt ttaatagaat gtaatcatat tatttactat attccattat
    12361 gtactcttta aatcctgaat cttcatttac ttgttctttt actatattaa aacctttttt
    12421 attataaaac acaactgctt ttttattatc tttatatact gctaagctta gacttttata
    12481 ttttttagtt gcataatcta aaagtttacc tccgatacct agattttggt atttgggctt
    12541 tataaataaa gctcctataa agtttttatc tattatgctt ataaatcctt ttatttcatc
    12601 tccatcatca tatacaaatg tatctgatat aggtatatat tcgtttttaa cagtattata
    12661 gttattttgc cagtattctt tacttataaa gtcatgtgct ttgattgtac ttttttccca
    12721 tatttccatg attttattta tgtctttact gtttaatttc tttatcataa attttgtttc
    12781 acctcatttt tgtattgatt ttataatgtt tgtaggtaag tgtattttat ttagatatga
    12841 tttagttaat ataaggtgga tgttttagta tatgctattg ttgattctac aattttatat
    12901 actgctttat taatataaaa taagtttcta aatactcgtt gatattgcta atattctact
    12961 tatctaccac ttagttgata taaaaattga aacttcacta tctaataatt taattaatga
    13021 tatgctatta catttatcta tttcataacc accataaatc ccaggtgttg aatttataaa
    13081 tataccagct tgctctaaat acatcttgta actttttatt tgcctttcac ttacttccaa
    13141 ctcttctgat aattctttgc atttcatttt gcctctgctt tgaattaata tcatcattct
    13201 aagtgtatta gctaatttac taatgagtaa ccccccccta ataacattaa ttgatatttt
    13261 tattatttat ttctacacat atgtacatat aacctcttta tattttatat aagtagaatt
    13321 tttttataat tttgacattt accatattat attttatatt tgtacaaaat tttaatagtt
    13381 aatacaataa aaaatattac tgaaaaaata aacatctata attccagtaa tattaattaa
    13441 ttttaaaccc tttttattat catttaataa tagtaactaa aaattgacta aatttaacct
    13501 tatctctttt aaataattat ttcttacaat aaaaaaataa actatttgaa ccaagaacaa
    13561 gcttcccatt accaaaacag ctgatgatgc tacttctata tcaaaagaat ttttaagtgc
    13621 agtaagtgca aatattgaat gtataacagc cactacataa ggaaacaaaa atactattcc
    13681 aatctcaatt gttgaagctt ttttaatctc attatatgtc atacccaatt tatttaactg
    13741 ttcatacttt ttcttatcaa cttggcaatc catataaaat ttattatata aaaaactact
    13801 tgtagtaaca
//
LOCUS       DAYAKB010000088        13657 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.088, whole genome shotgun sequence.
ACCESSION   DAYAKB010000088 DAYAKB010000000
VERSION     DAYAKB010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13657
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.088"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..334)
                     /locus_tag="ACGI3L_003123"
     CDS             complement(<1..334)
                     /locus_tag="ACGI3L_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HFG9198819.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCYGKIITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNG"
     gene            complement(445..1122)
                     /locus_tag="ACGI3L_003124"
     CDS             complement(445..1122)
                     /locus_tag="ACGI3L_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198820.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(1135..1830)
                     /locus_tag="ACGI3L_003125"
     CDS             complement(1135..1830)
                     /locus_tag="ACGI3L_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HFG9198821.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(1882..3081)
                     /locus_tag="ACGI3L_003126"
     CDS             complement(1882..3081)
                     /locus_tag="ACGI3L_003126"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HFG9198822.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(3342..5387)
                     /locus_tag="ACGI3L_003127"
     CDS             complement(3342..5387)
                     /locus_tag="ACGI3L_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198823.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(5798..6607)
                     /locus_tag="ACGI3L_003128"
     CDS             complement(5798..6607)
                     /locus_tag="ACGI3L_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9198824.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(6691..7224)
                     /locus_tag="ACGI3L_003129"
     CDS             complement(6691..7224)
                     /locus_tag="ACGI3L_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9198825.1"
                     /translation="MSGAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(7374..8723)
                     /locus_tag="ACGI3L_003130"
     CDS             complement(7374..8723)
                     /locus_tag="ACGI3L_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase TldD-related protein"
                     /protein_id="HFG9198826.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSITSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(8735..10117)
                     /locus_tag="ACGI3L_003131"
     CDS             complement(8735..10117)
                     /locus_tag="ACGI3L_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HFG9198827.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIESGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            10361..11575
                     /locus_tag="ACGI3L_003132"
     CDS             10361..11575
                     /locus_tag="ACGI3L_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9198828.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            11752..>13657
                     /locus_tag="ACGI3L_003133"
     CDS             11752..>13657
                     /locus_tag="ACGI3L_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198829.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIED"
BASE COUNT         4671 a         2289 c         1594 g         5103 t
ORIGIN      
        1 gaccattttt atacatatat tcatatacat tttcagaaga atatggtgtt atagaatgtc
       61 cacaattacc atttatagtt gttgtaactc cttgttttag aaacttttca aatttaccat
      121 ctagtattgc tactatttct tcatgaacat gagggtcaat aaatccaggt gttataattt
      181 ttccataaca atcaatctct ttatttgtat tgctatttat cttagaatct atttttgcta
      241 ttaagttgtc tttaattgct atatctccat aaaaaccagg attacctgta ccatctatta
      301 taaatccatt ttttaagatt aaatcatata tcaaaatatt ccctccttaa aaaccaattt
      361 ttaaataatc ttaatgtaat ttttatattt gaaaatcaaa ttattaaatt tcatatttga
      421 aaattcacta ttatttcatt gtaattagtc actaagctta tctttataca tagctcttgc
      481 aattaatata gtaccaaata cacatataag aactactaga gactgtggta ttataccttg
      541 ctttgataat ataatagtca atacagatat tacaattgct actagaccta attttttatc
      601 ttgtaaaaat acttgtccaa aaactgaccc aaatagagct ggtaaaatta agtttaattt
      661 ttctactact tcagctggaa ttttagatag tacgcttcct cctaaaatta cccctatagt
      721 tagtatactt atattcacta aaatagatac agctattcct attgtagata ttatcgagcc
      781 ttcttctgta cctgattcaa cttctgctgc cttttgagct gctattgaac atggtagcct
      841 catattagat atattaccag aaagaaaact catataagtt cctgggatac ctaagattgg
      901 tgaataagaa actggttcta ttatgtaatt tggagcactc atactgacaa ttgccattgt
      961 acttgctaat aatgctgata ttggaggcat aataccaaat ccaaagctca aaattattcc
     1021 aggaactaat gctgctataa tacccaaaga tagtgttagt cttccatacc ttatcataaa
     1081 aggtaaatat tcttcattgt atatagattt tactttactc ataaaactcc ccccttatat
     1141 tactgaagct attatcattc cgctaaacat tgatattgta agcccccact ctcttaacca
     1201 ttttatattt ttcttctttt caagcataca caatattacc attatagcca ttccacttat
     1261 acatgcaatt gttccattat caaaacgcaa caccctatca gcatttagat atgcaaatga
     1321 acccaacatt gctcctagag atattattgg tataaatgat ttcttgccac tagatataac
     1381 attggttatc ttatctagtt tatgtccaaa tagtaatgtg aatattatcc atcctaaaga
     1441 acctaatatc atagtccaaa ctgcatttgt aaatgcaagt tttgtcattt caggagaacc
     1501 taaagttata cctaatgcat ctgttccaaa tccggctgac attgattcaa aaattacaga
     1561 acctataaat gataatctca tccatgctat aggcccaccc atagttacta taagcgatac
     1621 cattccagca aatatagtca ttgaaggccc aatagctgaa atagcactac tcttaacagc
     1681 tgactttatt tgtttatctg ttattcccat tgttttacca actttgcaag attttatagc
     1741 aaatataagg gattgtacca ctactattga tactgctact gtactcgcta tccacaaaag
     1801 tggatgatta gctaatttta aataatccat ttataaaacc tccctataaa tcctcaaatt
     1861 ttattaatat ttctaatata tctatttcca aacctgtttt agtactctaa gtatatttcc
     1921 acctagtacc ttctctattt cctcatcact atatccatgc tttactaaat atctaacaat
     1981 gttttttgaa gtttctgttg ggttctcaag accttttaca tattctactt tgggatgttc
     2041 ttttgttcct gttatttttt ttatatcaaa tttagcagct agtactgagt gtaattttac
     2101 atggtcgcca tatactgtat ctggtccaaa agctacatgg tctattccta ctaaattttt
     2161 aatatactca aaatgttcca taaatgactc tattgaatgt tctttattct tctctgttat
     2221 tgtagtatga ggtgctgctt ctacacctat aacccctcct tttttagcac atgctattaa
     2281 tacttcatct ggagttagtc tctttgtgtt ccataaactt cttgccccaa catggcttaa
     2341 tattattggg tccttgctat attctattac atcaagtgta gtttgaactc caacgtgaga
     2401 gcaatctatt gccattccaa ttttattcat tctttcaaca gctttttttc cgaaatttgt
     2461 aagacctcca tctttctctt cttttagtcc tgaacctaat gcattggatt cgctgtatgt
     2521 tatacccatt aaccttatac caaatccata cagtatatct attctatcaa gttcattttc
     2581 tattggtgct gcaccttcta atgttggtat caatgctact ttaccttcac ttttagctct
     2641 gtatatatct tctacttttt cacactttat aacaaaatct tgatgagcta aatcacatag
     2701 tctcatgcct aaatctatta atatatcatc ccatttccac cctgaatttg atgttatcgt
     2761 acatacacca tccattaaat tatcaaatat agcatcataa tatcctcttg ataatgcttc
     2821 ataagcacat ctttgtttac cttccctatt atattcaaat atatctcttt ctaggtgttc
     2881 tggaaataat actggatgtt catgtaatga tataaatatt ttttcatcca ctatactttt
     2941 aaccttagct tcttgaatat catctaattc aataaggtat tctttaactc ttttatctcc
     3001 tttacacatc tcaatagatg aaatatcttt tcctttttct aaataactat aggcttcata
     3061 tcctttgtaa gctgacttca taacaacatc ctccaagttc tacaattttt tatatttttc
     3121 ctatgtagca attgatgtgc caaaatataa attttaattg tataataaat cttgcaaaaa
     3181 ataaaaacag tagtaaggtt gatatttact actgttttat taaaaataat cttcttagat
     3241 tatttattca atatttttga attatcttaa tcttaaagat aattttattt atttctatcc
     3301 attataggga tttttttagg gtgttttgcc tttttagtcc cctatatcac tcccttaatt
     3361 tttacatatg atataaagtt ctttccttca tcagttataa aactaccttg tttttttact
     3421 ccagataaaa gtaaaccatg gctctttaac ttatctattc tttttctaat ttggtctaca
     3481 cttaaaacta tatctttttc ttttaaaatc tcttgcagtt tatttcttcc taataatata
     3541 tttttattat tccaagtttc tatactggtc aatatacata tactttcctc aaagaaatta
     3601 gattgtttga aatctaagat aattgaatcg aaattttcat taactaaagt attgtttttt
     3661 tcaaatctaa attgttctgg caaatgctcg taatctactc tatcttcctc aactatagta
     3721 tcaatataat aaattaaatt tttaagctct cttacatttc ctggccattc atacaatgtt
     3781 aaagcttgca ttgattcctc tgtaaaacat ttgttgctat ttatttcatc taaaaaatac
     3841 ttacttataa gaggtatatc ttccttacgt tctctaagtc taggtatctc tatatgtaat
     3901 acattaatcc tataatacaa atcttctcta aaagaacctt ctttaatttt tttctttaaa
     3961 tctttatttg ttgcagctat aattctaaca tctattggta taattttact tccgcccatt
     4021 ctcataactt ctttttcctg taatactctt agcaatctct gctgtacatc taaagatata
     4081 tcacctatct catctaaaaa aattgttcct gtatgtgctc tttcaaatat acccattttt
     4141 ccacctttta ttgctcctgt aaaacttcct tcatcatagc caaaaagttc actttcaata
     4201 agtgtatctg acaaagaaga tagattaact gcaacaaatg gcttgttttt tcttagagat
     4261 tcattatgta ttgcctgggc aaatatttct tttcctgttc cattttctcc aagtatcaac
     4321 acagaaaagt ctgtagttgc tatttttctt gcaatattaa ttttttcttt tattatttta
     4381 ctctcaccta caacactctc aaatgtatac tttgatacaa aaccttttga ctgaagttta
     4441 ttttgaatct tgtcctcaag cacttgaatt gcacttatat ttttaatgct tataatactc
     4501 tttattcgtt cattattttc ataaacattt actttattaa ttatcagttt tttgttattt
     4561 aaatttacta cttcatcatt aacttcatct tcttgaaaaa atattttttt gacaacctta
     4621 tcactaaata agtccataaa gttattagat ataatttcat tttggtctat tccaactaga
     4681 ttagaaaata ctttgttgca atatataaat tttcctaatt tatcaacaga agcaatacct
     4741 tcatctataa tctccaaaaa actcttcatg gttttattca tagttgtata atacctatat
     4801 ccacttactg tatcttcatt gtatttttcc ttaataatat gtagtttatc tatagatata
     4861 tttagttttg taaagatttc tataactgta tttatatcaa ttaccttatc acctatgtca
     4921 attatttgct ttatgttttg tggtatgctg tttctgcttc ccgtaataat tccaatctca
     4981 catttagact tatcacaacc tggataatat ggtattagat taatatgaat taatcctagt
     5041 tttctaatta tcttggcagt ttcatctgct gactctttat aagcatctat aaccataaca
     5101 tcagaatcat tttctatact tattatctga tttatatttt caatatttat agtacgatgt
     5161 actattacaa taggtatatt tttatcaata ttattatgta tatattcctt tatatcattg
     5221 tctgaacata ctacaagctc atagcttgac agttcaatat ttatcctatt tacatatacc
     5281 aagttatcta tattacaaaa ttctccaaat atattttcca attgttttga tatatctata
     5341 tttattttgt catcagttga tacaaataaa atattatgtt ttttcatagt cccacctcct
     5401 gtttaacgag tatagaaagt aataatttgg tctattgtag cactttttaa aaaagtttta
     5461 aatcttaaaa atcaaatttt gtaccattta ctattatttt ccataataaa ataatgtaag
     5521 ctatcttttt tcacatataa tttaatttct aaaacggtta gtttgacatt attggaatat
     5581 aaataaaaat ttaatataaa ttcgttaata tattaataca tttttaagaa tgacaaggaa
     5641 taaattataa caaattttag gaatatataa taatagggtc tcagaactta gttacaagtt
     5701 ctaaaaccct atttgtttag tgtaaaaaac atcataaaat ttagcttaaa tcttttcaca
     5761 taatattact ctttttctaa gtgataataa aatatatcta ttcctctaaa aactgtaaaa
     5821 attcctgatt aaatagttta agctcatcat agaatatagc atgaccacta tactcaaaag
     5881 tatataaaat tgaatcttct attttttcat tcataaaaac tgcaaattca tacggacata
     5941 tttcatctaa tttcccatga aatataccag taggcactct tacacatttt aaatcattaa
     6001 ataattcttc atctcttaaa gatacagcag ttccaatagt gccaatacct gatgcactaa
     6061 aaccaatatc attaaaccat cttctaaagc tttctggtgg atttgatgca aatacttttt
     6121 cgccaaaatc ggttaccatt tctggtctat cagtacatgc ttgtgctatc aatttattta
     6181 catcttcacg tgtcatacca tatggaaatt ctggaggtct ttgtacaaat gatggtgcag
     6241 cagctgcagc taataccaat tttgacactc catatccatt aaataaactc atatacctaa
     6301 gtacgattgc tcctcccatt gaaaaaccaa caagggtaaa gtcttttaat ccaatagcat
     6361 gtaccacctt ataaatatcg tctgctaatt ggctataagt atatcctcct gatgttgcat
     6421 cagatttacc aaaacctctt aaatcaattg aaactgttct atatccgagt tttggcaata
     6481 tatttgtttg atattcaaat atcttatgtc ctaagggcca accatgtata aaaagtacag
     6541 tttttttagc actcggattc aaatcatata ctgctatgtt tatatcattc acatatacat
     6601 aatacatatc aacagcaact cccttcaaga aaatgtatga tggttatttt atatatatga
     6661 ataaaatgat gaataactaa attttcaaat ttatttacaa tacttctcta ttgccttttc
     6721 aaataaactt acatgaagtt tttcatctag gattattcta tttaatatag cttttatata
     6781 agggtcttca ataagactta tatctttata ataattatta atagccacat gctccaaatg
     6841 caaatctagt tttaatctgt tacaaataga atttccataa catacaaaac caccattcca
     6901 atatgcacca caagaacttg tagaacctct atatacagga tttccaccca ataatcttat
     6961 agtctttgct aatatctcca tatgtaacat ttctgttata gatatattta tccacatttc
     7021 acttaactct ctatgcgttt catctaaatc aaaattatgg tatagatatt gatttacact
     7081 cgtaaattca cttgatactc cagcatagtc atccatcaat aattctgcat aatacttatt
     7141 tggacctaaa acttttatct ctggatatgg ctcatcactt gaatatccat ttcgcttgtg
     7201 catgtcataa tgtgcaccac tcataatatc tcctccttta aatttaatgt atgatattaa
     7261 ttgtatgcat cacaactttt tcatataact tagataataa aatctactta aataataaaa
     7321 agccatatta attaaaatta acatgacctt ttatccacaa aattactttt taattattca
     7381 tcttttccag ctactgatag ctctttaata acaactgaag gtgaacctat actactcatt
     7441 ggaaattcta aatcttctcc tatagcttca atatctttca acaggtcaaa atagtttcct
     7501 gctactgtaa tttgctccac tggaaatact ttttttcctt ctttgatata aaagcccttg
     7561 gcagctaaag aaaagtctcc tgttactgaa tttgcacctg aatgaagtcc tgcaaagcta
     7621 gtaaccatca atccttcatc tatatccttt ataatttcat ctaaagattt atctcctttc
     7681 tctatataaa aattagttgg atatatgctt ataggtgatg aatatgaaga ttttattcca
     7741 tttcctgtag tctttacacc tgccttatta gccgttttta agttatgaag taaagttata
     7801 agctttccat ttaaaacaac ttctttttta aatgtagcta ctccttcatc atcaaaagga
     7861 gtagatgcca taccattttc taaaagtggg tcatcaacta ttgtaactat aggagatgct
     7921 atcatgtctc cttctctatt tttcaataaa gataatcctt tttgagctga atctgcatta
     7981 aatatcccag aaaatgtgct aagcaaagat accatagctt cattaagcaa tatagtttta
     8041 tatttacctg atgtaatact cttaccacct actttagata aagcattatc aacaccaagt
     8101 tttgctatct cacaaggttt tatttcttca atagaatttg ctatattata tcctattcca
     8161 tcatattttt gtccattgtc ttctatgata ggaactacaa accctataag catattagtt
     8221 ttattgctta aattaagacc tttagtatta gatataccat tacttgatac agaataagat
     8281 atagtacatt tagataaatt taccacctta tctgaataag ctttagtctc tctttccatt
     8341 tctaaagcta aatcaatcaa cttatctgcc tctaaatttt ctagctcttt agaataagtc
     8401 tttacatcat tatagtgctt atctccttca tatataaatt gtacatcttc attttcaata
     8461 gtgtttactc catcttttac attttttatc aacatatcaa cagctttatc atctaaaatt
     8521 tctgtataag aataacctat ctttccattt accttacctc taaaagataa accaaaagat
     8581 ttatcaagat tgtatttctc aacttctcct tcatatatat ttatacttaa attttctcct
     8641 gtataataat atatttcaca ctcttcaaaa ccttcactta gagccttttt aaataatata
     8701 tctttaaaat ttttaagttc cacaattatc cctcctatct tccacctaca gtaatttctt
     8761 ttacccttat cataggttgg cctacattag ttggtatact tcctgatgat gagccacaca
     8821 tcccctgagc ttgttttacg ttattcccaa ccatatctat attcataagt atatcgctac
     8881 cttttccaat taaactagca cctctaactg gctcttgtat ttctccattt tttattaagt
     8941 aaccttctga aactgcaaaa ttaaactctc ctgttacagg atttacagaa ccaccaccca
     9001 tttttttagc ataaagtcca tctggtattg actttataat atcttctggt ctatcttctc
     9061 cagcagcaat ataagtgtta gtcatccttg aagttggtgc aaatttgtag ttttgtctac
     9121 gagaacttcc tgtaggattc attcccattc gtctaccatt aagtttatct atcatataag
     9181 acttcaaaat tccactttca atcagtatat tcttttgagt tggatttccc tcatcatcta
     9241 tattcataga accccagtag tttggtattg taccatcatc tatagctgta atctttgtgg
     9301 aagcaatctg ttgacctaat ttatctgcaa atacagagtt cccctttgca actgatgtag
     9361 cttccaaaga atgtccacaa gcttcatgaa atattactcc accaaatcca ttatctattg
     9421 ctaccatcat attacctgca ggacaatttt tagcatgcaa catagtatgc gctactctag
     9481 ctgattcttt tgcataatat tctgggtcta tttcttcaaa tatttcaaac cctttacaac
     9541 ctccaggacc ttcaaatcca gtttgatttt cattaccctt agatgcaatt gaacttatcc
     9601 ctagtctagt tcttattctt ctatcctcaa catatatacc ttcagtgttt gcaattaata
     9661 ttttttggtc tttatccaaa taactgacac ttacttgaga tatatcatta ctaaattctt
     9721 ttgcactctt atatgcaacc ttcataacac ttactttatc tttatttcct attgaatttg
     9781 gataaatttt tatattatgt atgttattta ttttaatact gtcatttaat attacacttt
     9841 ttccatcttc caatttacct aaagcaacag cagctttgta tgctacatcc aacagactat
     9901 ttaatgaatt gtcacttgta taagcatata tacttttcaa tcctttaaat attcttattc
     9961 ctataccata atttcttcca cctattgcat tttctacttt attatctatt aaactaatag
    10021 aattatttat agtgtcttct tcaaaaatct cagcaaaatc tcctccagta attagacatt
    10081 tttctaatac cttagaagct atattttttg aaagcataaa tttacctcct actttaaatt
    10141 tttaattaac ttttattcaa tctttttact tgttaacaaa cattatatac tatattactt
    10201 aaaataaggt aattatgaat atattataca tatgttttat actaaaatgt tatcacattt
    10261 tatctataca tacccatata actagataat taaaatgtat aatattattt gctatagaaa
    10321 ataatacact catacataat aaattttagg agtgaagtat atgaatcaag aatatgtaaa
    10381 aggaaatcct atttttacta atattaataa agttccaaga caatttccat accttactga
    10441 tgatattgat actgatgtta taattgttgg tggtggcgta actggatgta tttgtgctta
    10501 ctatctagct aaaaacaata taaagtctgt cattcttgaa aaaggaagga ttgcacatgg
    10561 aagcactagc gtgacaactt ctctattaca gtatgaatta gatgacaatt tgatagattt
    10621 aacagaggtt atgactctaa aagatgctct aaaagcatac aacctttgta cttcagcact
    10681 tgaagaatta gatacattta tagagctata tggaaataag tgtgattatg ccaaaagaga
    10741 tactctactt tatactgcca acaaacttga agttaaggct atcaaagaag aatataactt
    10801 aagaaaagaa aatggatttg atgttgaata tattgatgaa tccacaaacc cttttagctt
    10861 tgatttaaaa tcaggattga tagcaaagaa tggaggacga gaattagacc catataaata
    10921 tagtcaccat ttgattgatg taagtttaaa aaatggtctt caagtatatg aaaatacaga
    10981 agtaaaaaaa gtagatttat caaatgataa ggttactgct gaagtatcgt atggatacaa
    11041 agttcatggt aaaaaattaa ttgtagctac agggtacaat acaagtttat ttacaaaaag
    11101 aaattttgca actaagtcaa atacttttaa tatagcaacg aaaccactta aaaacatagc
    11161 ttcttggaaa aacaacattt taattagaga taactgtgac ccatataatt atctaagaac
    11221 tactaaagac aatcgattaa ttataggtgg tgaagatgta agttttgatg atatagaaaa
    11281 tgaaacttta gccaatgaaa agtatgatat tttagaacaa agattgaaaa gtatgtttaa
    11341 ggatataaaa gacattgaag ttgaatataa atattgtggt tgttttgctt caactttaga
    11401 taatttaggt tttattggtc cagataataa aaataacaat ctatggtatt gcttaggtta
    11461 tggagcaaat ggtatactct ttgcaatatt aggaggtata atgttaagtg aattatatct
    11521 tggcaaacaa aataaaaata tgaaattatt taaagtagat agatttgata aatagatatt
    11581 atatattaaa agactgtaaa aagatgaaac tttataattc taaaagttaa ctttgataca
    11641 gtcttttata atgttccttt taaaaatact ttatttataa ttaaatataa agtaaaatgt
    11701 taaaatataa ctaataaaat ttagtcataa gataatattt aagtttattt gatgaaatat
    11761 ggaggaatta ttatgaagga aatactcgtt attgctccca ctaaaggaac ctatgaaaaa
    11821 tcaattcaca tagttaaaaa aaacaaatat acaaatattg atgttgtatt tggcaatcta
    11881 aaagaaggta tacctcttgc tgaaaaaagt attaatcatg gtactagaat tatcataagc
    11941 cgaggtggaa cttacaatat gttaaaagct acttacaata tacctatagt tgaaattaaa
    12001 gtagatgctt atgatattat aaaaagctac aaggaggtaa aaaattccaa cgaaccattt
    12061 ggaataattg gatttaataa tgtcatctac ggtttcgata ttatagaaga aatattgaat
    12121 aagaaaataa ctatgattga aattgaaaaa gaagaagaaa tttatgatgc tatagaaaag
    12181 tacagaaaga aaggtataaa cacatatata ggagatacca ctgttgcaca tattgttaag
    12241 agacttaatt gtaagggaat attaatcgaa tctagagaag aaaacatact tagagccatt
    12301 caacaagcag aacaaatact cgaagcaacc aaggatgaac aaaaaagaag attacagata
    12361 gaagctatga cagattttgt acatgatgga ataataacag ttgataaaaa ttttaaaata
    12421 acattattta ataagagtgc tgaaaaaata tttggtataa aaaaagaaaa tgcactttat
    12481 cataatgttg tagatgttat cccaaacaca gttcttccac aagtagttga gactatggaa
    12541 cctcaaattg gtgaaataca aaatataggg agtacaaaaa ttattacaaa tagagttcca
    12601 ataattgttg atggtcagat tcaaggggct gtttcaacat ttcaagatag caaggagata
    12661 agttcttttg aacatacaat aagaaggagc ttattaagca aaggtctatc tgctaaatac
    12721 acttttgatg atataattca tgctagtgaa aagacaaaag attgtataga acttgcaaaa
    12781 aaatatgctt gttatgatac tcctatgatt attactggag aatctggagt tggtaaagaa
    12841 ctattttgtc aaagtataca taactatagt aagcgtaaaa atgcaccttt tgttgctgta
    12901 aattgtgctg ccatacctcc atctctaata gagagtgagt tttttggtta tgaggaaggt
    12961 tcatttacag gtgctagaaa aaaaggtaaa gcaggtgtat tcgaactagc acatgaaggc
    13021 acaatcttcc tagatgaaat aagtgaaatc cctcttgaac ttcaaggtcg attattgagg
    13081 gtattgcagg aaaaacaagt tatgagaatt ggtggtgata aagttattcc tatagatgta
    13141 aaaattatct gtgcttcaaa taaagactta aaaaatatga tgcgcaatgg tttatttaga
    13201 caagaccttt attttagaat aaatatacta acattatatc ttccttcatt aaaagaaaga
    13261 aaagaagata ttataaaatt atcagaattt tttatacata aatattcaag caaatacaat
    13321 aaaacgcctt taattatcac tccaaatatt aaaaaggcac ttcttgaacg agaatatgaa
    13381 ggtaatataa gggaattgga aggtatgatg gaaagggctg ttattgtgga atcatttgac
    13441 tcgattttat tagaaaagct tagcaatgaa tatacaaata atatagttga taaagataat
    13501 agtgattttg aatgcagtaa tttagattta aaaactttag aaaaaaaata tatctataaa
    13561 atttataacg aaaataatag aaatactaca aaaacctgtg aaattctaaa gataactcgc
    13621 tccactctat ggcgtaagtt aaaagaaata gaagatg
//
LOCUS       DAYAKB010000089        13641 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.089, whole genome shotgun sequence.
ACCESSION   DAYAKB010000089 DAYAKB010000000
VERSION     DAYAKB010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13641
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.089"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            14..412
                     /locus_tag="ACGI3L_003134"
     CDS             14..412
                     /locus_tag="ACGI3L_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198830.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(535..1557)
                     /gene="ccpA"
                     /locus_tag="ACGI3L_003135"
     CDS             complement(535..1557)
                     /gene="ccpA"
                     /locus_tag="ACGI3L_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HFG9198831.1"
                     /translation="MKMKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEV
                     IKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANT
                     YSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYT
                     VSTSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKS
                     LIKYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVA
                     GFNDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRES
                     VTERKK"
     gene            complement(1804..2004)
                     /locus_tag="ACGI3L_003136"
     CDS             complement(1804..2004)
                     /locus_tag="ACGI3L_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198832.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(2038..2217)
                     /locus_tag="ACGI3L_003137"
     CDS             complement(2038..2217)
                     /locus_tag="ACGI3L_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198833.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(2399..2605)
                     /locus_tag="ACGI3L_003138"
     CDS             complement(2399..2605)
                     /locus_tag="ACGI3L_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198834.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(2653..3078)
                     /locus_tag="ACGI3L_003139"
     CDS             complement(2653..3078)
                     /locus_tag="ACGI3L_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198835.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            3250..3477
                     /gene="acpP"
                     /locus_tag="ACGI3L_003140"
     CDS             3250..3477
                     /gene="acpP"
                     /locus_tag="ACGI3L_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFG9198836.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(3621..4625)
                     /locus_tag="ACGI3L_003141"
     CDS             complement(3621..4625)
                     /locus_tag="ACGI3L_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFG9198837.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(4639..5541)
                     /locus_tag="ACGI3L_003142"
     CDS             complement(4639..5541)
                     /locus_tag="ACGI3L_003142"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFG9198838.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(5736..6911)
                     /locus_tag="ACGI3L_003143"
     CDS             complement(5736..6911)
                     /locus_tag="ACGI3L_003143"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFG9198839.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(6998..7843)
                     /locus_tag="ACGI3L_003144"
     CDS             complement(6998..7843)
                     /locus_tag="ACGI3L_003144"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HFG9198840.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(7941..8738)
                     /locus_tag="ACGI3L_003145"
     CDS             complement(7941..8738)
                     /locus_tag="ACGI3L_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HFG9198841.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(8757..9767)
                     /locus_tag="ACGI3L_003146"
     CDS             complement(8757..9767)
                     /locus_tag="ACGI3L_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFG9198842.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(9786..10568)
                     /locus_tag="ACGI3L_003147"
     CDS             complement(9786..10568)
                     /locus_tag="ACGI3L_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HFG9198843.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(10627..11763)
                     /locus_tag="ACGI3L_003148"
     CDS             complement(10627..11763)
                     /locus_tag="ACGI3L_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009272751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HFG9198844.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(12472..12939)
                     /locus_tag="ACGI3L_003149"
     CDS             complement(12472..12939)
                     /locus_tag="ACGI3L_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFG9198845.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(13018..13560)
                     /locus_tag="ACGI3L_003150"
     CDS             complement(13018..13560)
                     /locus_tag="ACGI3L_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198846.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
BASE COUNT         4260 a         2570 c         1462 g         5349 t
ORIGIN      
        1 aaggggtttt tttatgaaaa aattagatac agagtcatta gaaaaaatgg ctaaacaaaa
       61 aaatattgac aaggataaaa tagaaaagat ggctgatagt tacaaaggaa aatcagaaaa
      121 tgaacttatg gaggaactta taaaaatagg taagaaccta gatggcagag atgaagtagt
      181 atcaaaattc aaagcatttt tagatgaaaa tcaacgcaaa aaactggata atataatgga
      241 aaaaatctca gatgcagaaa accaaagaga tactaaacca gctaaaacta agaaggctaa
      301 acctactaaa ggtaagtcaa attcacctgc accaaaaaat acaccaggta gtcaacaaaa
      361 aaaatctaaa agtttattta agaaaactaa aaagtctaac cctcatgaat agataaaaat
      421 aaactattta agtaattaga taattatttt tagttaatct attattaaat ttgatattat
      481 tgacataaaa aatcaggtag tgccttaggc actacctgat tgattttaat agttttattt
      541 ttttctttct gtaacacttt ctctatcaac aattctataa ggtaattcta ttttcttatt
      601 ctcaattaat tccttattta ttaactttat aaccattctt attgctactg ctcccatatc
      661 gtatagaggt tgatatactg tagtaagttt aggtctatac attctagcta tcttaacatc
      721 attaaatcct gcaacagata tgtcttctgg aaccttatat ccagcatcac atatagcatt
      781 tatagcacct atggcagcct catcacctgt tacaaaagcc gcatgaggta ttattccatc
      841 atctaatagt tctttcatac tattgtatcc actctcataa tcagttccac catacttaat
      901 caaactcttg tctaattcta tattgttatt tgaaagtgct ttctcataac cagcaagtct
      961 ttccatttct aaaacagtat catctttact cgtcattata aaagctatct tttcatgacc
     1021 tttctttata agatgctctg tcatatcaaa agtagcttct tcgttgctag tacttactgt
     1081 atatatatca taatttctag cagttttact tatatatgtc gctggtattc cacaattttg
     1141 tatatagttg atatgttctt gttcaactat ccatgaaatc ataactatac cttccacttg
     1201 ttttgctctc aatagattta tactcttaag ttcttgttcc ttatcagagt atgtattcgc
     1261 taaaagaata tcatagtcat acattttagc aacctcttct atcccattta acacctcatt
     1321 aacaaaagaa tctgaaactt ctggaactat tacccctatt aattgactct tctttgttac
     1381 taagcttcta gcaagtggat ttggtatata tccagtctct tttataacct ctaaaacttt
     1441 ttgtttgact tcatcagtta caggttttga atcatttata actctagata cagtagatat
     1501 tgacactcct gcttgtttag caacatcttt tatcgttata ttgcctttca tcttcatcct
     1561 ccttatttta ctaaatttat ctaaaactga accaaatttt tgaaggttcc tattttaact
     1621 acatttatat aagtttttat tttaccataa aagcaagtac atttaaatac attatatttt
     1681 atattatacc ctatattcaa caaatttaat aatattcatt cttaatttaa atcatattaa
     1741 aaaataaaat aaaaaaatgc tggtataaaa taccagcatt tttttattct aatgatttaa
     1801 gtattagcag ccgcaaccta cttcaccatc aaagaatcca ccacatgaac aagttattag
     1861 caataatatt aagaaaggta tccatgacat tatgtcaatg tctctccagc aatcttcaaa
     1921 agctaagaat aggaagaata gtactattat ccaccatcct cctccaccaa agcatccttc
     1981 ttctccaaaa aatctatcta acataacaaa gccctccttt ttttaataac tgtgttctta
     2041 ttctaagcat ccaccacagc agcaaagtat taataaaact attaggaatg gtatccatgc
     2101 cattatgtca aattctgccc agctatctcc aaaagctaag aataggaaga atagtactat
     2161 tatccaccat cctcctccac caaaacatcc ttcttctcca aagaatctat ctaacattat
     2221 acgttacctc ctgttgatat tttgttgagc ttttcgctcc taacatatac tatgcatttg
     2281 gtttccattt tgctaatgta tttttactat ttttttaaat tttttaattt gaactaaaaa
     2341 aggtaaaacc ataacttgta taagttactg gttttaccta tttaataatc aatatttttt
     2401 agcaacaaca accatcatcg aagttaaata ataacaatac tattaatata acccatatcc
     2461 atatattgtc atcgcataat aagtcttcta aaatgtctgt gcataatagt aagaatacta
     2521 taactattat tatcaacatt ttattcccaa aaaatccttc gcatcctcca aagaaacgtt
     2581 ccatattgtc ttctaatttt gtcataacta atcctccttg aatcattaag agactaagtt
     2641 ttgtctcttt aattaaatat atgtagtaat agacagataa gttacttcta aaaagttttt
     2701 attgattagt ttatttattt ctttttcacc aagtttattg tatctatcaa cttcatccag
     2761 ataatctttt ttctcctctg atatagtata gattaaactt tctattgatt ttattttgta
     2821 ctccttatat ctttctatca agaaggatgt ttttgaattt tctattcctt tctttacatg
     2881 cattaacctt gatatgtagt cttctttttc attagataca taactctcct tttcagctac
     2941 atcttcaagg attaaattgg tctccattac ataatcctct atacgttgca tatctaaagt
     3001 tattgaatta taataaaaat ttactgctat aagtaaaaac attcctactg aagttagtaa
     3061 tagtcctaca tatttcatag catttcctcc taagttatat ttgttatcaa taaagtttat
     3121 tcatcaaata atactttatt actacattta taaaatttta ttatttttta tagattccat
     3181 attgaaaaat tcttgatatt atattaaact aacattaaaa ttaattaaaa ctgctttagg
     3241 aggcttaaaa tgtttgagaa aataaaagaa ataatagcag aacaattagg ggtagacaat
     3301 ttagatgaga taactatgga agcatcttta atggacgact tagaagctga ttcattagat
     3361 gctgttgaaa ttataatggc ccttgaagat gaatttggaa tagaaatacc agacgaggaa
     3421 gctgagaact ttaaatgtat tggtgatata tgtaaatata tcgaagaaaa caaatagtat
     3481 cgttttgtct acaaatataa atagtctgtg taaacttcta cataataaat tatattagag
     3541 ttcgcacaga ctagattaca tttatttaca atatataaaa tacacgctct tatatttaat
     3601 ttatatacta agtatataaa ttacttttct tcataaaacg taacattctt tattattata
     3661 tctatagttc catcttgatt ttgttttaca gtatacttca ttgggtcttc aaaatcagtt
     3721 agattccctt ttatgtcaaa accattatcc gtttttatac ttcttttttt aagctttttc
     3781 tcaacccatt ttttatctat actaaaactt tcgtcaagac ctttttcttc catatgctct
     3841 ttaaagctat cctttaactc atcatcttta attgaattat caacaaagtc atttatatca
     3901 acttcatgtt tttccttcag tgtataattt aatatacttc ttacatcttc agcttgcttt
     3961 atatcattac taagagcatt ggttatccaa ttttcagctg tatttttaaa taccttggtc
     4021 ttgtacttat catcatctat ttttttagca tttaaaaatt ctgttacaaa cttagattct
     4081 gacccttctt tttcagcatc cttatctaaa agccttagat gaaactcatc atttatacca
     4141 cttagactaa tcaaagctcc ttgcttttgt cttaaagtct ctgggatacc aatttcattt
     4201 gaaaccattt gaatattaaa tttatcatcc acaaattcaa ttgaatgagt gtacaacttt
     4261 ttataatcta atttcagtat tgctacactc ttttcatctt taatagtgta taaacaaatt
     4321 gccaaatcac aagattctag tgcagcatta attttcataa cgtcaaacaa gtaagatgca
     4381 atttctttag aatttttcaa aaaagtactt tcatcatata ttatttgttc acaacagttt
     4441 ttaattaaat tgtcattata atctttaaaa acaccttttc ttaaatcctc atcttttgca
     4501 attcttttta tagctttctg gaaaaaacca tccacttctt gattaacttt gccttcaaag
     4561 tcatttaata ttggaacatc actatttttg tccaaaacat gtattataaa tttatgtatt
     4621 atcatatata tcaccccatt atcttaattt cgatattaac tctttcatat cctctggtat
     4681 atctgcttta aatttcaatt tttcttttgt tcttggttgt tcaaactcta gcttatatgc
     4741 atgaagtgct tgcctattta ttagctcttc atctacataa ccatacaact catcacctat
     4801 tattccatga cctatatgag ccatatgtac tcttatttga tgtgttctac cagtttctaa
     4861 gcttacttct aatacagttg cattttctag tctttctatt actttatagt gagtaacaga
     4921 tgactgtcct ctttcatcta ttatcctctt tattgaatct tctgtaggtc tataaattgg
     4981 ctcatctata gttccctcat tttcttttat aattccatca actactgtta tatacttttt
     5041 ttcaacttta ttttcactca ttgctgtaga caaagtatga tgtgcataag cattttttgc
     5101 tactataact aaccctgaag tattcatatc taacctattt acaaatctta tttttacgtt
     5161 ttctttttga ttatctatat agtaactaat accatttgct attgttttat catagtggct
     5221 ttttgttggg tgaactacca taaacggagg tttattcacc ataattatat caaaatcatc
     5281 ataaattatc tgtaaattta aatcttgagg ttcaaaattt gctttttcct cgtctatttt
     5341 tacttctatt aaatcaccac tatacacctt taaactcggt tttttatata ctccatttac
     5401 taaaacactc ttttccctct tcatttttga taatgaccta actgagaaat ttagcttgtc
     5461 caataaaact tcttttaaag tcatttcttc ttcatttgta tacgatataa gattatatct
     5521 ttgattctct tttttaaaca aacttttacc tactttcttt tatatcttcc tactttttat
     5581 atcttcaaaa tcatgatatt atatatttta cactattttt gtttaataga taataattat
     5641 ttttaactat aaaaacctgt aagaataaca aatagttatt cttacaggtt aaattcataa
     5701 ttaaatattt aatttgtaaa tattataatc taaaactatc tcttaactat taaagtagtt
     5761 cccattcctc cacctataca aagtgtagca agaccagttt tagcatctct tctcttcatt
     5821 tcatataaaa gtgtagtaag tattcttgct cctgagcatc ctattggatg tcctatagct
     5881 attgctccac cattaacatt aactttattc atatctatat ttaagtctct tattacagct
     5941 acagattggg cagcaaatgc ctcattagct tcaactaaat ctatatcttc aatagtcata
     6001 ttagcagctt ctaaagcttt tttagttgct ggaactggtc catatcccat tattttaggg
     6061 tcaacaccag ctgttccata agaaactata gttgcaagag gctctattcc tagttcttca
     6121 gctttttctt tagccattac tactagcata gcagcaccat catttattcc tgatgcatta
     6181 ccagcagtaa ctgttccatc ttttttaaat gcaggtctta acttagcaag tttctccatt
     6241 gtagtgccag gcttaatata ttcatcttta tctactacag tgtcaccttt tcttcctttt
     6301 ataacaacag gaactatttc ttcatcaaat tttccttcag cttgagcttt ttcagcttta
     6361 ttttgacttg caagagctaa ttcatcttgt tcttctctag ttatattcca ttgctctgct
     6421 atgttttcag cagtaatacc catgtgatag ttattaaata tgtctgataa tccatctttt
     6481 atcattgaat caacaaaagc agcatcaccc attcttgcac catatctcgc acttggtact
     6541 aaataaggag acatactcat gttttcagct ccaccaacta acattatatc agcatcacct
     6601 aatgctataa gttgagatgc cattgaaaca gatcttaatc cagaaccaca aactatattt
     6661 atagtcatag ctggtttttc tactggtatt cctgctccta atgctatttg tcttgctata
     6721 ttttgtccaa gacctgctgt aagtactccc cctaaaagag attcatctat catatctgga
     6781 gttatgttag ctctttttat agcttcttta gctgctgtta cccctaactc taccgctgaa
     6841 actgatttaa atgctcctcc aaaacttcct actgctgttc tagctgcact ggcaattact
     6901 acttctctca tattcattac ccccattaaa ttagattttt catatatccg aaattgtttt
     6961 ttaaacaatt ttatttaaac ttttaattcc caaattctta tttattataa tcatagaatc
     7021 ctatcttagt ttttcttcct aattgattag ctctaaccat tttagctaaa agtggatgag
     7081 gtctatattt agtatctcca aattcagtat ataaaacgtt cattatagct aaaacaacat
     7141 ctaatccgat taaatcacct aatgctagtg gtcccattgg atggtttgct cctaatttca
     7201 tagcttcatc tatttcttct ttacttgcaa caccatctgc atatatacca acagcttcat
     7261 ttatcatagg tataagtatt ctatttacta caaatccagg agattcagat acatctactg
     7321 gtactttatt gatactctta gataattcaa atactgtatc aaaagtaact tttgatgtta
     7381 actgaccact tataacttca actaatttca tcataggaac tggattaaag aaatgcattc
     7441 ctataacttt atctggtctc ttagtagaag aagctatttc tgttatagat aatgatgaag
     7501 tatttgttgc caagatagta tcttctttac ataattcatc tagtaacttg aaaacatctt
     7561 tctttatatt catgtcttct acagatgctt ctattattaa atccatatct tttaaatctt
     7621 catagttagt agttgaacta acatgactta atatttctgc ttttgtagct tcatccattt
     7681 ttcccttagt aactaactta gttaaatttt tatctaataa agctaaacat ttatctatag
     7741 caccttgagt tctactcttt aaacatacat catgtccaca acttgcaaaa gtttgtacaa
     7801 taccacttcc catagttcca ctacctatta cagctaattt catagttata acctcctgtt
     7861 attttagtat ttatattctg ttaactagat taaaatacta tttaatctag ttaacagcaa
     7921 atatattttt aattagattt ttaccctttt ataaagttag cttctctctt ttcaacgaaa
     7981 gctgacattc cttctttttg gtctttagtt gaaaaacaaa gaccaaataa attagattct
     8041 atatctattc cagtatttat atcagtttga gcaccaagtt gtattgcttc tttagagtat
     8101 ctaactgcaa gctgagcatt tttagctatt atcttagcta atttctcaac ttcttctatt
     8161 aaaatgtctg gctcaacgac tctatttact agccctattt tttcagcttc atcagctttt
     8221 ataacttgac ctgtaaagat taattctttt gcttttgcca ttccaaccaa tcttgtaagt
     8281 ctttgagttc ctccatatcc tggagttatt ccaagagtta cttctggctg accaaattta
     8341 gctttagcag atgcaattct tatatcacat gccattgcaa gttcacatcc tccacctaaa
     8401 gcaaatccgt ttacagcagc tatcactact tttttactat tttctatttc tccaaaagct
     8461 tttgctccta agatactaaa atctttagca gctacagcat ctaaatcttt catgtatgca
     8521 atatctgctc cagctacaaa tgcctttcct tcccctgtca atattacaac atcaatagtt
     8581 tcatcattat taatatctac aaatacttca taaagttctt ctaaagtctt tgaatttatt
     8641 gcattaaggg ctttaggtct attcattttc actgtacata tatttccatc tacttcaaca
     8701 gctacattct cataaacttt aacatcactt gtactcataa taccctcccc aagaaattag
     8761 ttagctaaaa cttcaccttt ttcttttgca acacttaact gactgataag ttctggaagc
     8821 actttatgaa catctccaac tataccaaca tcagcatatt taaatattgg agcttctgga
     8881 tttttattta tagcaactat aaactcagca tcttccatac cagctatatg ttgtattgct
     8941 ccagatatac cacatgctat ataaaggtct ggtcttacag ttttaccagt ttgaccaact
     9001 tgtcttgctt tatctaacca acctgcatct atagtggcac gagaaccaga aacttctcca
     9061 cctataattt cagctaattc ataaagtatg tctaagtttt cttttccacc cattccacgt
     9121 ccagcagaaa ctaatatctt agcatcttct attttaactt gttttttagc ttcttttatt
     9181 acttgtacaa cttgaactaa tttatcagca tcattaaatt ctaccttgaa acggttaatt
     9241 acagcttctt tagtttcatc aggttcattt ttcttcataa cccctggtct aactgtagac
     9301 atttgaggtc tgaaatcttt acaaactatt gttgccatta tatttccacc aaaggcaggt
     9361 cttgtcatta ataataattt tgtatcttca gctactgcaa gacctgtaca gtcagcagta
     9421 agacctgtat gtattctagc agaaactcta ggtgctaaat ctctacctat tgaagttgca
     9481 ccaaataata caactatagg gtcagctgct tttattgctt cataagctgc ttttgtatat
     9541 ggttcagttg tatacactgc taaagcttca tcatctacta ctattacctc atctgcacca
     9601 tagtgtgcta atgtatctat taaaccttct accttactac ctaaaagtaa tgcagaaact
     9661 tttgtatcat aatcttttgc tatttctgta gcctttccta gtaattctaa agaaacagtt
     9721 tgaattacat tttctctttg ttctattact actaaaacgt tacccattct ttatcccccc
     9781 ttaaattata tgatatactt ctcttttaat ttatctatga taattccagc tgatgttttc
     9841 gcatcttcat tgtatattgt accagctggt ttaactgatt ttgtaaatga tttaaataca
     9901 ctagttggag aacctttaag acctaaatta gaagggtcaa cttctatatc ttttacagtc
     9961 catgtttcta ctacatcatt ttcgaaagca tcatatattc ttccaacttt catgtatctt
    10021 ggtgtgttca tatctttaag agttgttata aggcatggca ttttaacttt taagtcatgg
    10081 caacaatctt caaattgtct ttttactaat acatattcac cttcagtttt tatttcttca
    10141 gcatatgtta ttgatggaag atttaaatgt tcagctattt gaggtccaac ttgtgcagta
    10201 tctccatcta tcgcctgtct tccagctatt ataatatcaa aatctatatt ttttaatgct
    10261 cctgctaatg ctgatgaagt tgcccaagta tcagcacctg caaatgctct atctgttaat
    10321 aatatacctc tatctgcacc cattgctaaa gcttctttta aagccatatc tgcttgagga
    10381 ggtcccattg ttataacagt tacatgagca cccatttctt cttttaattt tatagcttct
    10441 tctaaacctg ctttatcatc agggtttatt atacttggta ctccatctct aattaaagta
    10501 cctgtattag gatctagttt aacttctgtt gtatctggaa cttgttttat acaaacgact
    10561 atattcataa atccttcctc catatctatt ttaatatcga cctattgtgt atattttaat
    10621 atttatctat tttaataatt ttcctgaaat aaccattctt tgaacttcac tagttccttc
    10681 atatatttca gttatcttag catctctcat cattctttct actggatagt cacgagtgta
    10741 tccatatcct ccatgaagtt gtacagcttt tgtagtaact tccatagctg tttcagctgc
    10801 aaataatttt gccattgctg cttctactcc ataaggtttt cctaagtctt tatttatagc
    10861 tgcttgatat acaaggtgtc tagccgcttg taccttaact tccatatcag ctaattggaa
    10921 ttgtgtattt tggaattttg ataatggtct accaaattgt actctttctt ttacatattt
    10981 aacagtttca tcaagagcac cttgtgctaa acctaaagct tgtgcagcta taccaattct
    11041 accaccatca agagtagaca ttgctatctt aaatccttga ccttcttttc caagtaaatt
    11101 ttctttaggt attctgcaat cctcaaatat taattcactc gtagctgaac ctcttatacc
    11161 cattttcttt tctttaactc caaagctaaa cccaggagtt cctttttcaa ctataaatgc
    11221 tgatattcct ttgttcccct tagatttatc agtcattgcc attactacat atatgtcacc
    11281 agctattgca tttgttataa atatttttga gccattaagt atgtattcat ccccgtctaa
    11341 aacagcagtt gtttgttggc cagacgcatc tgtaccagca ttaggctcag taagaccaaa
    11401 tgctcctaat ttttctccac ttgctaatgg tcttaagaat ttttgttttt gttcttcatt
    11461 accatattga tatataggcc atgagccaag agatgtatga gctgataata taactcctgt
    11521 agtaccacaa actctagaca attcttcaac tgccattata tatcctacag tgtctccacc
    11581 ttctccacca tattcttttg gatatggtat acccatcatt cctgcttttg ccattttttc
    11641 cactgtttca taaggaaatc tttcttcttc atcaagttct gttgctaaag gtttaacttc
    11701 attttcagcg aagcttacat atagctcttt aagcatctga tattttttag aatttaaatc
    11761 cataatagcc tcctcagtat tttataaata ttttattttc atttattaat taaaatctcg
    11821 gcaacatcta taataaggta tttgaatata cgtcgagaaa tttataacct taatcaaact
    11881 acgctctata tttatatgtg attatactaa ccaattatga cattaattta atcataaatt
    11941 gttaatttaa aatcaactat acttaaaaaa aatctcgctt tttggaattt tgtgaaattt
    12001 caagttagaa taagatttct ttcacactgg ttagagataa aataatttgt ttacgatatt
    12061 tatattaagg tatattaaac attaaatatt gtctgtacat ctgtttttta gccatgtaca
    12121 gaagattttt atcgtataaa aattatttta atagagctaa ataatcatat ttttatctga
    12181 ctatttttta tttttaaata tcttacatct ataatagtat cactcaaagg ataatttttc
    12241 aataatttct aattattttt ttaacaatat ttattacatt ttttccactt ttttgtcatt
    12301 tttttattgt ttcgaaaaaa aatcagaatt ttttaacttt attttggatt attagtttaa
    12361 attagatttt cctcttagat ttataaatat ttacacaaaa aaactacctc tgtatagatt
    12421 gtatacagag gtagtttttt actaattcct actatagttt actatatttt tttaccaatt
    12481 cttacaaaca tctacccatt tttcacactt agaaaacttc tccatttctt cacatgtaag
    12541 ttctattgca gagttactac tgccacatgc aggaaatact gtatcaaatc ttttcattga
    12601 atcatctaaa tagactttta tagaattttt taaaccaaat ggacagactc caccaatagc
    12661 atgtccagta aactccaaga cttcttctgg tgtcaacatt ttagccttac aattaaattc
    12721 agccttatac ttcttattat caatcttagc atcaccagct gtcacaatta aaattgcatc
    12781 atctcctatt ttaaatgaga gtgtcttagc tattcttgct ggaataaccc cagctgcttc
    12841 agctgcaagt tccacagtag cactagattg ttcaaattct aatatactgt cttccttgcc
    12901 aaattgttta aaatactctc ttacattact tattgacatt aaatacccct cctagtctga
    12961 acttttataa atttcatatt attcttaatt atatctataa ttgatttatt tttcaaatta
    13021 ttccataata ttagcattcc atgtatcatt attttttcca actactagat aaagtccttt
    13081 tgccattgga atattgacaa tatattctcc tttatactct acactcatac cagattcatt
    13141 aaagtaccta taatcaaaat ttagtccttt tggaattaca aaatcaacat aaccttgatt
    13201 atttggtttt attccatatt tcagagttct ttcagttata gaattttttt cattaaataa
    13261 atctacattt acatatgcag aacacttatt cattcccttt ttattttcca cacaattttc
    13321 aaacttcatt ttagcactgt ttaatttata actatattta ctattattgc ttattttaaa
    13381 tcttacaata gtaccaacat ctctacttct cctgctatca aaatcaaaaa caatttcctc
    13441 taaatgattt atttcataat ctttgacact taccatatct ctatatacta atttatttat
    13501 agctatgaat agtgtaaaaa tccccaaaat aaaaaatgaa acttttataa acttcttcat
    13561 ttttagtctc cttatatttt gtgctattgt gctataatat taatcaaaat tttaataatt
    13621 aaacttattc ttttttgaaa t
//
LOCUS       DAYAKB010000090        13354 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.090, whole genome shotgun sequence.
ACCESSION   DAYAKB010000090 DAYAKB010000000
VERSION     DAYAKB010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13354
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.090"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            110..301
                     /locus_tag="ACGI3L_003151"
     CDS             110..301
                     /locus_tag="ACGI3L_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFG9198847.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            456..1865
                     /locus_tag="ACGI3L_003152"
     CDS             456..1865
                     /locus_tag="ACGI3L_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9198848.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            1996..2685
                     /locus_tag="ACGI3L_003153"
     CDS             1996..2685
                     /locus_tag="ACGI3L_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFG9198849.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2688..3623
                     /locus_tag="ACGI3L_003154"
     CDS             2688..3623
                     /locus_tag="ACGI3L_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198850.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3620..4513
                     /locus_tag="ACGI3L_003155"
     CDS             3620..4513
                     /locus_tag="ACGI3L_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFG9198851.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4591..5337
                     /locus_tag="ACGI3L_003156"
     CDS             4591..5337
                     /locus_tag="ACGI3L_003156"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFG9198852.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5338..6171
                     /gene="rsmI"
                     /locus_tag="ACGI3L_003157"
     CDS             5338..6171
                     /gene="rsmI"
                     /locus_tag="ACGI3L_003157"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFG9198853.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEIRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6194..6898
                     /locus_tag="ACGI3L_003158"
     CDS             6194..6898
                     /locus_tag="ACGI3L_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFG9198854.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7086..7514)
                     /locus_tag="ACGI3L_003159"
     CDS             complement(7086..7514)
                     /locus_tag="ACGI3L_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFG9198855.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7551..8981)
                     /locus_tag="ACGI3L_003160"
     CDS             complement(7551..8981)
                     /locus_tag="ACGI3L_003160"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFG9198856.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9113..9697
                     /locus_tag="ACGI3L_003161"
     CDS             9113..9697
                     /locus_tag="ACGI3L_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HFG9198857.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9713..10234
                     /locus_tag="ACGI3L_003162"
     CDS             9713..10234
                     /locus_tag="ACGI3L_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HFG9198858.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10300..10546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10630..12567
                     /gene="metG"
                     /locus_tag="ACGI3L_003163"
     CDS             10630..12567
                     /gene="metG"
                     /locus_tag="ACGI3L_003163"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFG9198859.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12597..>13354
                     /locus_tag="ACGI3L_003164"
     CDS             12597..>13354
                     /locus_tag="ACGI3L_003164"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFG9198860.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKF"
BASE COUNT         5303 a         1523 c         2381 g         4147 t
ORIGIN      
        1 attttttgtc aaaaaaaaca aaaaatacgt atttcttttt tcatttcggg aaaactaaac
       61 acaggaatta tggactttat aaaaatttaa ttcttgagga gtgatataag tgaaaaaagt
      121 tgctttaatt ttagctataa taggtgcgct taactggggt gcaattggta ttctaggtac
      181 agacttaata ggtagtatct ttggtggaac atatgaaatg gtaagtagaa taatatactt
      241 cattgtaggt ttagctggat tatacttaat accaagttta atgtctgatg atagagaata
      301 atttatgctt ttatgttaaa tacctcattc taaatgttta gaatgaggta tttaatttta
      361 taaaaatatt aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa
      421 agaagtatta tgtaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata
      481 agattgtaaa tgaagaagta atatcttttc atatgcctgg tcataaaaag ggacaggttt
      541 ataaaaagtt aggatataaa gatatactaa aaaatttgta taaaatggat acaactgaga
      601 tattaggaac agataattta cactttccgg aaggaattat aaaaaattca caaaaaaaag
      661 catcaagagt atttaaaagt gattatactt gctatttagt aaatggtagt agctgtggaa
      721 tacaatctgc aataatgtca gtatgtagtc ctaaaagtaa aataataaca aatagagact
      781 gtcatcagtc tgttataaat ggatgtattt taggagatat agatatagag tatgtgcctt
      841 gtgagataag tgaagagaca aatgtcttaa aagggatatc tataagtaat gtgattgata
      901 taatagataa aaacttggat gcaaaagcag tactgcttac ttatcctaca tattatggaa
      961 tgacatatga tttagaatac atatgtaatt atgcacatag caaaaagatg gtagtgatag
     1021 tagatgaagc acatggtgcg catttagggc ttagcgagag gcttcctaaa acagctcttg
     1081 agcaaggcgc agatatagtt gtacagagta cacataaaac tcttccagca tttacacaat
     1141 cgtcaatgat acatatacag ggagaccgag ttgatataga taaaatattg aacatgttaa
     1201 gaattacaga atcttcaagc ccttcatatt tattattatc ttctctggaa ttagcagtag
     1261 atatatatga aaataaagga aaagaattaa tggaagagct tttaaataat attataactt
     1321 tcaaaaataa agttgattca aatattaata tatacgacac aaatgataaa acaaaaatat
     1381 ttatatcatc taaaaatatg ggtttaacag gttatgaact agaaaatatt ttaagaaaca
     1441 aatataacat acaagtggag ttatctaatt attatggagt tcttttaata tgtacaatag
     1501 gaaatactgt tgaggatttc tctagtttag aaacagcatt aaacaatatt gtaaaggaag
     1561 actttaaatt tgaaaagtta gaaaataaaa aataccctgt tgttattcca aagaaaatat
     1621 taacacctag agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagcatag
     1681 gtaaagtttg tggtgaatgt atagttccat acccacctgg aataagtgta atatctcctg
     1741 gtgaagtaat aagtaaagaa ataatagact atctaatgtt ttgtcattct aaaggcatga
     1801 ttgtgagtgg attgaaagat gtagatttaa attttataca aataatagat ttagaagaca
     1861 tttaaaaatt atgatataaa agtagataga agtagatagt ttaaaattgt gaagagaaat
     1921 aaatagactg cttatataga gctatctaat aaaagtacta aaaaagtaaa aagtgtttgt
     1981 atggaggata tgaaaatgaa aggtaagtta ataattatag agagtggttc agatgcaagt
     2041 ggaaaggcta ctcagacaga aatattatat gaaagattaa aaaaagaagg ctatatgatt
     2101 aaaaaggtag aatatccaaa ttatgaatct ccatcatctg ccttggtgaa aatgtaccta
     2161 aaaggagact ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt
     2221 acagctgata ggtatgcatc atttaaaacc gattgggagg agttttacaa tgaaggtgga
     2281 ataattatcg cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat
     2341 atttgtgata gagaagagta tttaaattgg ttagctgatt atgaatttaa tttatttaag
     2401 ataccacaac ctgattgtgt tatattttta gatgtgccta ttgaatttag taaaaagctt
     2461 atggagaata gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac
     2521 atagagtatt tagagaaatc ttacaacaat gctttatata tagcagataa atatgattgg
     2581 aaaaaaataa attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa
     2641 atttataaaa tagttcttga ttcaataaaa cctatggaga gataaatatg tattttgaaa
     2701 atattatagg gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac
     2761 ttaataatgc gtatatgttt gaaggaatgg atggaatagg aaaaaagaaa tttgcagatg
     2821 aattatcaaa actattactt gattatgaaa atctcgaaaa tagtccagac tatgtactca
     2881 taaaaccaga tggaaatagt ataaaaatag ctcaaatcag aaatttacaa tcagatatag
     2941 taataagacc tcataaagac tataaaatat atataatcaa taatgctgaa aaaatgactg
     3001 tggaagctca aaatgcactt ttaaagacgc tagaggaacc tccaaactat gctataataa
     3061 tcttagtcac aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa
     3121 taaagttctc acctatacca attgaagact taaaacgtta tttgataaat acaggtatag
     3181 aagaagaaag agctcaatta ttggctattt tttcgagagg aagtattgag aatgctctaa
     3241 atctatctca gtcttctgag ttttcaatga tgagagaaga tatacaacag tatattcaga
     3301 taatgttaga taaaaacata gtggagattt taaatatacc aaataatatg gaaaaatata
     3361 gaggtaagat tatagcttta ttagatatga tgataaacta ttttcgagat atcatcctat
     3421 taaaagaaaa tgtaaacaag aacatgttaa taaatgtaga taagctagtt ttcattcaaa
     3481 atatgagtgg aaaaattagt tattctcaat tgtccaagat tattgatata atagaagatg
     3541 caaagagtaa aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa
     3601 atatatacga ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa
     3661 aatatattat tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga
     3721 aactgcaaga ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag
     3781 cgaattagtt tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt
     3841 atatctagaa aataaggaaa aggcaaaaga aacttttgag ttgtgccaac aaaaaataaa
     3901 agaacatgag ttaacaatgt ttttaataga ttgtgagtat acatttgata ggaataagtt
     3961 gattttttac tttacagcag aaggaagaat agattttaga gaattggtaa aagacttagc
     4021 tgctatattt aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc
     4081 tataggaggt ctagggcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt
     4141 tcaaccagtt tcaataaaaa tggcaaaaga ccaaagtcta tctctaaatc caacaaaaat
     4201 atctggaata tgtgggagat tattctgttg cttaaaatat gagcatgatg tatatagtga
     4261 agcaatagaa aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg gaaaaggaaa
     4321 agttgtagaa gtgaatcctt tattagaaca aattaaagtg gaatttcaag acaagacagt
     4381 aaagatatac acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg
     4441 tggtggtaaa tgtaaggata atgatggatt agatgaagcc acactaagag agctaaagaa
     4501 attagaagat taaatttaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta
     4561 aagttattaa tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat
     4621 gatttacaat taaaaggcct taaaattata caagatacta atggtttttg ttttggtata
     4681 gatgcagttt tattagccaa ttttactaaa ataaaaaaag atgccaaagt agtagatttg
     4741 ggtactggaa ctggaattat acctattttg atagctggaa aaagtgaagc taaaaaaatt
     4801 attggcgtgg aaatacaaga agatgtatat gaaatggcaa ctcgttctat aaaattaaat
     4861 ggattagaag aaagagttga gattataaat gaagatataa aatacataga caaagtctta
     4921 gacataaatg gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata
     4981 aaaaatccaa atgataaaaa agcaatatca agacatgaag taaggtgcaa tttggaagat
     5041 gtaattagag ctgcatccag attggttatg cctagaggaa aattcttcat gatacataga
     5101 ccaacaagat tggttgatat aataacttta gggagaaaat ataaattaga accaaaggtt
     5161 attcaatttg tgcatccaag acctcaaaaa gcaccgaact tagttttggt tcaatttgta
     5221 aaagatggaa ggccagagct taaaatattg gacccattgt atgtttatgg agaagatggg
     5281 aattatacaa aagaattaaa agcaatatat aataataaag atataggaga gttgtaaatg
     5341 agtgggaaat tgtacatatg tccaacacca ataggaaacc tagaagatat aacatataga
     5401 actttaagaa cattaaaaga agtagacttg attgcagcag aagatacaag acatagtata
     5461 aaacttttaa atcattttga aatctcaaaa ccactaacta gttatcatga acataataag
     5521 gattcaaagg gagattattt gataaataaa ctaattgatg gtgaaaatat agctctgata
     5581 agtgatgcag gtatgcctgg tatatctgac ccaggagaag agataataaa acaagctata
     5641 caaaataaca tagagataga agtattgcca ggtgcaacag cctttgtaac ggctttagtt
     5701 ggctctggta tggacacaca tagatttgtt tttgagggct ttttagatag agataaaaaa
     5761 gttaggaaag cacaattgga agaattaaag gaagaaagta gaactataat tttctatgaa
     5821 tcaccacata gattgaagga tacactaaaa gatatgctta aaattcttgg taataggaat
     5881 atttctataa atagagaact tacaaaaaaa tatcaagaaa taataagaga aaatatagaa
     5941 actaccataa aaatatttga ggaaaaagaa ataagaggag aatttgtatt aatagtagag
     6001 ggttttcatg gtgagaagtc aaagaaagaa aattatgatg ggcttacaga tagggaatat
     6061 gttttaaaac taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa
     6121 gatagaaagt taaagaaaga tgtggtttat aaacaagttt tagatttata aaacctgaat
     6181 ctgaggtgat tttatggaaa tagggaaaat tataatagag agtttaaaga gggaagatac
     6241 acataaaata tttatagaat tagataataa gcatgaatta gaaaaaataa ttcctaaaat
     6301 aagctgtatg aagtctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacattc
     6361 tataaacgca ttaaaagaat tagaaatagt attaaatgat aaggattttt ttccaataca
     6421 tctaagaaaa catgtgtcaa actatttaaa cacatatatt gaagaaggaa taaataagtt
     6481 acatgtatta aagctgggaa catttttaca tgatataggt aagcctgaca gtatgacctt
     6541 agatgaaacc ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga
     6601 caatatggga ataaagttag agttatcaac agagacatat agacttataa gtaaatatgt
     6661 aagatatcat atgatacttt tgtctctata taagaaaaat gatttgagta ggaaagaatt
     6721 aattaatgta tttaacttag tagatgagga cactataggt gtaataatgc ttgggtatgc
     6781 agatatagtg tctacagtaa aattattggg caagagtgga gaagtcagtg tgttaaagac
     6841 atatatggaa tatattttaa caaattactt gtataagagt aattatacac atgtataaat
     6901 ttagttaata taattgagtt ttagatgatt aattgaagtt tgaaatatac ggatttcaaa
     6961 aacataaaag aagttgtctt tgttgtaaaa ttatgaaaga caactttttt tatatcaaaa
     7021 attgaaattt tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat
     7081 ttatattaca atattgattt tgcttgtatt ggcgttgata gtataacaga ggtcttagta
     7141 gaaccaattt tctttatagt atcaatcaca ttttctaact cgtacatatc ttttacaatt
     7201 acttttaaaa gtaagcaatc atcacctgtt atatggtgac attctacaat cctagggtcc
     7261 tttgcagctg actcaataaa ttctgtatat ccattgcttg gaagagaaat atgaataaat
     7321 gcctttataa ctctgcctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca
     7381 ccagactctt ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt
     7441 tttcctaagt ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa
     7501 tctgtaacat ccataaataa acagtccccc ttaaataaaa ataattaatg ctataaaact
     7561 tttttagaat ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta
     7621 taaatgtgtg gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt
     7681 acatgatttt ttatttcaag aacagctttt ttattatatt tgcatctgcc ttttatatac
     7741 aatggtttaa gaagctcttt aactttgtaa tttgtaaata ccttcgtttt ccatgtataa
     7801 gtaggatgga agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc
     7861 aaatctgcct ctgccttatt gtcttcgtta tatattctta taactttctt gtaaccagga
     7921 ttatttattt tttctggatt ctcagaaatc tttatcttag gttcaagaac tcctttttca
     7981 caagatgcag ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc
     8041 tttgtaccta ctccccatga atttatagta gctccttctg ctttaagtga tgttatggta
     8101 tattcgtcta ggtcattaga tgcagtgatg ctgatatctg aaaagccagc attatctaat
     8161 tgttttttag cttctttaga taaataagct aaatctccag agtcaagtct tatacccata
     8221 ggtttgtatc ctttttcaga aatatttttg aatactttta ttgcattagg aactccactg
     8281 tttaatacat cataagtatc tacaagtagt aggcatttat ctggataaac atcagcatat
     8341 gcttggaatg cttcaagttc attatcaaat ttttgtaccc aactgtgagc ttgtgtacca
     8401 attataggta tatcaaacat tttccctgct agtacgtttg cagttccagc acaaccacca
     8461 actacagcag ccctagcccc atatatccct gcatctggac cttgtgcacg acgtaatcca
     8521 aattcaaata cagggtctcc ttgagctgca aagcaaactc tagaggcttt agtagcaata
     8581 agagactgaa aattaactat tgttaacaat gctgtttcaa taagttgagc ttgatataaa
     8641 ggtgccttaa cagtaattaa tggctcatta gggaacatga tagttccttc ctcaacagca
     8701 tatatatctc ctgtgaattt aaattctttt aaaaatttta agaacttgtc agaaaataaa
     8761 tttaagtttt ttaagtactc taaatcttca tctgaaaaat gaagattatc tatgtattca
     8821 acaacctgat caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa
     8881 aacatatcaa atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata
     8941 gtaagctgat ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat
     9001 tattaaatat taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa
     9061 ctttcaagta taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat
     9121 aataggaaaa atatggtttt atatggtatc gataggaata ataggaagct tgatttctaa
     9181 aaatatgggt gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc
     9241 aataagtcta gctggtatca tggcactctg gatggggata atgaatatcg caaaagaatc
     9301 aggtttaatt gaaaagatag gtcaaaaact aaatcctata atgagaagat tatttccttc
     9361 tattccaaaa ggtcataaag caatgtctta tatagttatg aatattgctt taaatatgtt
     9421 gggtgctgga aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt
     9481 gaataacaag aaagatacag ccactaatga tatgattatg tttatggtaa tcaatatatc
     9541 atctatacaa ataattccat ttaccataat caaactaagg atggatatgg gggctcaaaa
     9601 tccaagtgaa ataattttta cgactttatt tgcaaccata atatctacag cagtagcaat
     9661 aataacatgt aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat
     9721 attttcaaac ttacttatac caataataat tctgtacata gtaatttatg gtaaatataa
     9781 aaaaatagat gtgtatgata gttttgtaaa aggagcaatt gatggattaa aagctgcatg
     9841 ggatatccta ccatatataa taggtatatt tttggcaata ggaatattca aaactggtaa
     9901 aggtcttgat atgttagaat ggctatttac accaatagca aatatgatga gtataccaaa
     9961 agaattaata ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tagggatgta
    10021 cagtgaactt gcaaatagag ttggaatagg aagtttagta gaaaaaatgg gtgctacgat
    10081 tgtaggttct tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat
    10141 aaaaaatact agacatacat tatcatgtgc tatgattagc catgttgcag gtgtcatagc
    10201 agctgttttt atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt
    10261 ataatatagt gattatatag aaacaaatag taatacaaat tacaagctat gaaaagaaga
    10321 gtaaataaag gttttttcta tcagagagct aggttaggtg aaagctagtg tcaaaagctt
    10381 tattgaagat ggtcttggag ctttttatct gagcaagtgt gctagggtaa aacggttgga
    10441 cacgttatag tctactaagg tatctataaa atgtttctac atttcatgtg aaacataact
    10501 attatagatg aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag
    10561 gcgatttttt attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag
    10621 gtaaataaca tgagcaaacc gagtttttat gtaacaacac caatatacta tccaagtgga
    10681 ggattacaca taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag
    10741 cgtttctgtg gatatgatgt aaagttctta acaggaacag atgagcatgg tgaaaaaatt
    10801 caaaagaaag ccatagaaca aggaatgtca gagatagagt atcttgatgg aatgataaaa
    10861 gatataaagg ccttatggaa tactatggat atatcttatg atgattttat aagaactaca
    10921 gaaaaaagac atacagacat aatacaaaag atatttacta aactatatga gcaaggtgat
    10981 atatataaag gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa
    11041 tctcaattac tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa
    11101 gaagaatctt atttctttag attatctaaa tatgaagaca gattaaaaga gttatttaaa
    11161 gatgatagtt tctgttttcc tgctgctaga aaaaatgaaa tggtggcaaa ctttttagac
    11221 aaaggattag aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct
    11281 tttgatgaaa aacatgtaat ttatgtgtgg gtagatgctt tatgtaacta tataacagca
    11341 ttaggttata tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcaa
    11401 atagtaggta aagaaatagt gagattccat acaataatat ggccagcgct tttaatggct
    11461 ttaggtctag aagttccaaa acaagtattt ggacatggat ggatactatt tgctgatgat
    11521 aaaatgagta aatcaaaggg taatgtggtt tatccagaac ctataataga aagatatgga
    11581 atagacacac ttaagtactt cttattaaga gagtttgcat ttgggcaaga tggaagttat
    11641 actcatagaa attttgtaac gagaataaat tatgatttag caaatgattt aggaaactta
    11701 ataagtagaa ctgtagctat ggttgaaaaa tacaataatg gtataatacc aacagcaaaa
    11761 gtttcaactg attttgatgc tgacttaaaa gaacaagctg tttcaactag agaaaacttt
    11821 gaagctgaaa tggataaaat gcaattccat gaagcattag agagtgtatg gaaattagtt
    11881 agaagaacta acaaatatat agatgaaact atgccttggg cactagctaa agatgaaacg
    11941 aagaaagatg aattagacac agttttatat aatttatgtg aatctataag aataatcgca
    12001 acactaataa atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata
    12061 aaaggtcaag atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa
    12121 aatgtaaaag tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagagata
    12181 gaagaattaa ctaaaatgtt ctctgggaaa cctccagtag aagaaaaacc tttagagcat
    12241 aaagaagaaa ttactattga tgatttagac aaaatagagc ttagagtagg gaaaataata
    12301 agctgtgaaa aacatccaaa agcaaataaa ttattagtat cacaagttaa gattggacca
    12361 gaaacaagac aaatagtatc aggaatagct gaatactata agccagagga tttagtagga
    12421 aaagaggtta cagtggtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa
    12481 ggtatgatat tagcagcagg tgatgatgga gacccatatg ttttaccatt tacacaaggg
    12541 gctaaagatg gatgcgaggt tcgttagtag gtaattaaat agtaaggaga ttaaagatgt
    12601 tatttgactc acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta
    12661 ttggttcatt aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagaga
    12721 cgtcgataac agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttgggg
    12781 tacatccaca tgatgtatca aaactagatg atacagcaat agaaactcta agaaaacttg
    12841 caactgagaa tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt
    12901 attctccaag agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc
    12961 taaaacttcc aataataata catgatagag atgcacatgg agatactttt gagataataa
    13021 agaatactaa aaatcctgaa ataggatgtg tacttcattg ttatagtggg aatgtagagt
    13081 tagctagaga atatgttaag atgggttgtt atatatcaat tccaggcacg gttactttta
    13141 agaataataa aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag
    13201 agactgattc accatatatg tcaccagagc cacatagagg aaagagaaac aatccttccc
    13261 aagtatcttt tgttgctgat aagatagccc aggaaaaagg gatatcttat gaagaagtat
    13321 gtagagttac aaaagaaaat gcaaagaaat tttt
//
LOCUS       DAYAKB010000091        13061 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.091, whole genome shotgun sequence.
ACCESSION   DAYAKB010000091 DAYAKB010000000
VERSION     DAYAKB010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.091"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            202..1107
                     /locus_tag="ACGI3L_003165"
     CDS             202..1107
                     /locus_tag="ACGI3L_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol lysyltransferase
                     domain-containing protein"
                     /protein_id="HFG9198861.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            1116..2300
                     /locus_tag="ACGI3L_003166"
     CDS             1116..2300
                     /locus_tag="ACGI3L_003166"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9198862.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            2415..3716
                     /locus_tag="ACGI3L_003167"
     CDS             2415..3716
                     /locus_tag="ACGI3L_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HFG9198863.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            3670..4713
                     /gene="holA"
                     /locus_tag="ACGI3L_003168"
     CDS             3670..4713
                     /gene="holA"
                     /locus_tag="ACGI3L_003168"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFG9198864.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(4900..5166)
                     /gene="rpsT"
                     /locus_tag="ACGI3L_003169"
     CDS             complement(4900..5166)
                     /gene="rpsT"
                     /locus_tag="ACGI3L_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFG9198865.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            5744..6265
                     /locus_tag="ACGI3L_003170"
     CDS             5744..6265
                     /locus_tag="ACGI3L_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9198866.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            6299..7075
                     /locus_tag="ACGI3L_003171"
     CDS             6299..7075
                     /locus_tag="ACGI3L_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFG9198867.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDKI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            7417..8370
                     /gene="gpr"
                     /locus_tag="ACGI3L_003172"
     CDS             7417..8370
                     /gene="gpr"
                     /locus_tag="ACGI3L_003172"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HFG9198868.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            8388..9407
                     /gene="spoIIP"
                     /locus_tag="ACGI3L_003173"
     CDS             8388..9407
                     /gene="spoIIP"
                     /locus_tag="ACGI3L_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061783 - peptidoglycan muralytic activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HFG9198869.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            9438..9689
                     /locus_tag="ACGI3L_003174"
     CDS             9438..9689
                     /locus_tag="ACGI3L_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198870.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            9971..11776
                     /gene="lepA"
                     /locus_tag="ACGI3L_003175"
     CDS             9971..11776
                     /gene="lepA"
                     /locus_tag="ACGI3L_003175"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFG9198871.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            11925..>13061
                     /locus_tag="ACGI3L_003176"
     CDS             11925..>13061
                     /locus_tag="ACGI3L_003176"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFG9198872.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEF"
BASE COUNT         5227 a         1337 c         2199 g         4298 t
ORIGIN      
        1 attttatttc tcaataaaaa atcactccat tcattacatg tttatataaa tttatgatgg
       61 gtaatataag atatatatga cttattatat tttatatttt aaacaatata aatgaaatta
      121 ataccataat aaaattggag ttttttatat atacaaaata aaatttttaa aattaagcaa
      181 taaaaaaggt aggaggattt tatgtttttc aaagatattg aactaaattc aaaaaaagag
      241 ttagacccat attttgattt agtagattat gaagcttgtg agtactgttt tagtacttta
      301 tatatgtggc aacatgttta taagacagga tattatatag gtgaagattt tgccgtttta
      361 gttggggaat acgaaggaga tagcttctca atattaccac ttgctaaaaa agataaactt
      421 ccagaagttg tagattttgt ccttgaatat ttttctaaaa ataataaaaa aatatactta
      481 agaggtatta ctactgaagt agtagagttt ttaaaagaaa aatatccagg tagatttgag
      541 tatatagaag aaagagattt atttgactat atttatgatg cagaaagttt aagaactcta
      601 gctggtaaaa agaatcaaaa gaagagaaac catataaact atttcttaaa agagtatgca
      661 ggtagatatg aagctaaatt attagataaa gaaaactttg atgagtgttt agtactaatg
      721 aaggaatggg aaagtaataa ggaagaaaat aatgaatttg atgaaagtat ggatgatgaa
      781 ttaataggta tcaaaaagat atttaaccat tatgacatat taaaagataa ggtaaaagtg
      841 tttggtgttt atgtagatgg aaaattagaa gcttttagta taggagagct tttaaatcca
      901 aatatggcat tgattcatat agaaaaagct aatcctgata taagaggtct gtatccattt
      961 ataaatcaac aatttttggt aagtgaattt aaggacgttg agtttgtaaa tagagaagaa
     1021 gatttaggta ttgaaggatt aagaaaagct aaactttctt atcatccttg cagatttgtt
     1081 gaaaagtaca gtgttaggga ggcttaatag actatatgga gattaggtat gctaaagaag
     1141 aagagataga aagtataaaa gagatttgga gttattgttt taacgatacg gagagtttta
     1201 tgaagtacta ttttaatgat aaatataaat ctgaaaatac tgtagtagct ttagatgaag
     1261 gaaaaattat ttcttctctt cagctaaatc agtataagtt attactaaat agcaaggtat
     1321 ataatacatc atatgtagta ggagtttcta cacttccaga gggaagagga gctggatata
     1381 tgaacaaagt aatgaaattt actttaaacg aattgtataa aaaagggcaa ttagtttcta
     1441 tattgatgcc tattgactat agactttata gaagatttgg atatgagcat tgttacgacc
     1501 agattgaata tactattaac acagatgatt taaaaaattt taagtcaagt ggaaaaatga
     1561 taaagtctaa tttatcacaa attgatgatt tgatacaaat agatagaact tttttaaatg
     1621 aggttaatgg taatgtgtta aaagatgaac attattatga aaacttattt aaagagattc
     1681 aaagtgaaga tggattttta tacattcatg aaggaaatga aaaagatgga tatatagttt
     1741 attttcttca ggaagataaa atgtttgtca gagagttatt ttataaaaat atagatgccc
     1801 ttaaatcaat gcttaaattt atatataatc acaatactca atgtaagata gttactatat
     1861 ctactcctac aatagataag ataagattta tattagacaa ccctaaagat agtgatataa
     1921 aaataaaacc ttttatgatg ggaagagtta taaatgtaaa gaagtttatt gaagatatag
     1981 atattgagaa tgatattaat agctcattta atttattaat agaagacaag tttatagatg
     2041 aaaataatgg tctatttaaa atttctatac agaataagaa ggtatctgta gagcagttag
     2101 ataaaaaagg tgcagaaaag cctcaagaag attttgatat taaattagat ataaatacct
     2161 taacacagtt atcattttct tatatagatg taaatgaagc tattttctta aatgatataa
     2221 aagatgtttc agaagaaaca ctagaaacac ttaattgtat tttttctaaa aaaaataact
     2281 atataaatga atatatatag gtagagtacg ttaaaagatt ttaaaaatct tttgacgtat
     2341 ttttttgttt agataacaat ttatcttgtt taaaaatttt ctatttgaaa ataatctaaa
     2401 taatatactt ttatatggga gtgattataa ttcaaataag aagaccatta ttaattatat
     2461 taatgtttgt ggtagctata tcatttatca ttacaaataa cacaaaaaac gacgaagaac
     2521 ttaatgataa gataataact atacaaggag ttgtcaaagg aaaaattgaa aagaaaagat
     2581 acaatcagta caaggtaggg gtttttctaa taaatgatta tacaaaaaat aaaaatttga
     2641 agattggtca gaaagttaat attacaggta aattcaaaag tttagataaa atgaagtatg
     2701 atgattttga ttatggaagg tatataaaaa gtactggata taaaggtata gtgtatataa
     2761 ataactataa aattattgat aaaaataaac tttactcttt aataggggaa ataaagtttt
     2821 atattagtaa aacttatagg tacttatata agaaaaactc agattttata aattctatac
     2881 tattagcaga agttgaaaat ttgactgagg aacaaaaaga aatttttact agaactggaa
     2941 ctagtcatgt aatatctata tcaggtcttc atacaggaat attatgtgta attatatcct
     3001 ttctattaag aggtataaat aaattgtata aattattaat actgtcgatt tttataactt
     3061 tatattgtat aatggtaggt gcgtctccat ccataattag gtctatagca tttgttatga
     3121 ttttttattt atcaatattt attgatagaa agaaagatgg aatatcggca ttgtctctaa
     3181 ttgggataat tttaattatg aataacccct atgttatata taatgtaagt tttcaattgt
     3241 cttttttagc tacactttct atattaatat tctataataa aataaatagt attataaaat
     3301 taagtatggt atcattgaca atatcatcaa atatattaac tttacctata atttattata
     3361 catttaaagg tataccattg ctttcaatta taggaaattt aattatagta ccatttgtgg
     3421 gagtaataat gtatttaagt attgcaagtt taatcgtatt taaagtaagt gtagtaatag
     3481 ctaaaattat atcttttttt aatagtacat ttatagaaag catatttttt ttactagaaa
     3541 aaatcagcaa tttaagtttt gcatacatta atatagaaaa tcctaaattt tatattgttg
     3601 ttatttatta cataggagtg tttttttaca tattttacat agaaggaaaa gagataaagg
     3661 agcaagagaa tgaattacaa ggatattata aggaatgtaa aagagaaaaa ctttgaaaaa
     3721 atgtatcttt tttatggaag agagtattat ttaattgaga atgcaataaa agcatttaaa
     3781 gatagtctaa acgagggaat gcttgatttt aacttagata taatagatgg gaaggaaata
     3841 gtcttaaatc agcttataag ctctatagaa acacttccat ttatggatga tagaaagata
     3901 gtaataataa aagactttga actattaaaa ggaaagaaaa agaattttac agatagtgat
     3961 gagaaatact taatagagca tttagacaat attccagaca ccacaactat agtttttgtt
     4021 gtatatggag atgtagacaa aagaaaatca ttagttaaga aaataggaaa caatggaatt
     4081 gtttttgatt gtgataagct ttctgatatg gatttgttta aatggataaa aaaatctttt
     4141 gctttaaatg atgttataat agataattct caaatcatgt attttattga acaagaagga
     4201 tacagagata agagtagtga aaagacatta tctgatttag aaaatgaaat aaataaaata
     4261 agttcatttg ttggtaaagg gaataatgta accaatgatg taattgataa attatctcaa
     4321 aaaaaagttg agaatgatat attcaaatta atcgattata ttggagaaca aaatgcttct
     4381 aatgcaatga aaatattaaa tgatatgata caagaaggcg aatctgtatt aggtatattt
     4441 tctatgatag caagacaatt taaaataatt atgcaagtaa gacagttaca acttgatgga
     4501 tattcaacaa aacttatagc tgataaatta aaaatgcatc aatttgttgt aggaaaagca
     4561 ttaaagcaaa ctaaaaattt ttctgatgat ataattgtgg aaatattaaa ctatatatta
     4621 gaaagtgatt ataaaataaa gacaggtctt ataagagata ctttagcagt tgaaatgttg
     4681 gttagtagat actgtaaaag agaagcaatt taaaaaatct atatattaat aaaaaataaa
     4741 tagcaagata tgttatagtt cagagtagat gtaagctaaa ttaagtttga tatacaatca
     4801 actataatat gtctaactat ttatttttta ttgtataaat ttacaaaata aaaaacccct
     4861 acataggggt tattatatat aagaaatata aactggtaat taagcgttca taccgtttaa
     4921 tttttgagct aatttagcta cttttctagc tgcagcattc ttatgtatag ttcctttaga
     4981 agctacttgg tatattcttt tttgagcgta ttggaactta gcaacagcat cctctctgtt
     5041 tccagctgca acagcatctt cgaatcttct tattgcagtt tttatttgag attttctaac
     5101 tctatttaaa gcagttttct tttcgataac acttattctt ttcttagctg attttatatt
     5161 tgccaccgtg ttcacctccc tgtatttttt tatcatattc atcgtcaaca tattagattt
     5221 taacagaaat aaatctaaaa atcaaggatt attatttata tattttaata atgtttttta
     5281 ttttgatttt ttagactgta aattgtgtat aaataatttg caatatcttg tttttaaatt
     5341 ggtatatttt gtgttttaaa tattttgaca tatataaatt aatattttat ttttgtaaca
     5401 aatattttga gataatacaa actattaaca tacattttga tagtatttcc aataattata
     5461 agataataca agaaattact catttttgta aatttaatga aaaattataa aaatataaat
     5521 ttatatgctt aattaagata atttttttca ttagtatgta tgatagatgc atcaaacaat
     5581 ataactaata tgttagaagg ttatatgtaa ttaatgtcag tgtttatata gaatagcatt
     5641 tgtagcattt attatagttg taattactat ttatatcata gacttgaata gtctaaaaaa
     5701 atagactata atatttttat agactaaaga aagggctgat aagatggaca tagcaaaact
     5761 aattttaaat cctgcaaggc ttcgtatttt acaatatatt cgactttatg gcagtgttcg
     5821 tacatctgat attgtaaagt atttaaatga tattcctcgt gcaacagttt atcaccatgt
     5881 aaaaatttta gaagagaaca atatgattga agtaattaaa gaaaatcgtg tgcgtggtac
     5941 tattgaaaag gtttatgcac taaaggaata tacaacatct atggaaggag agaccttcgt
     6001 tgcactttct acagcatttt atgtaggtct gatgcaggaa atgaatgaat actttagcag
     6061 aaaagagcaa gaccataaaa aggataatgt atttttctct tcagcattac tatatatgag
     6121 tgataatgaa tatgaaaatc ttcttaaaag tatagctgat ttattgaaac catatataga
     6181 acaaaaacct aaatcaaatc taaaacttag aaaactttca attatatctt ctccacctgt
     6241 agctgataat gataaaacaa aataacatgc aacccatttt tataaaagga ggttatatat
     6301 gaaatttcat gagtttggaa ataaaaacag accacatatt atgttgattc atgggggagg
     6361 gaatgcatgg tggaactatt tgcgacaagc agaagttttg tctaacaaat atcatgtgat
     6421 acttcctaca ttggatggtc atggagaaga atatgaaaca acatacattt ctacagagga
     6481 tacagcagat aagttgatat catatataga tgaaaattgc agtggacatc ttttcgcttt
     6541 gtgtggggta tcacttggtg gtcaaattgt catggaactt ttatctcgaa aacctaatat
     6601 tactaaaaaa gcaattattg atggtagtat ttgctaccca agacctctta tggcaaggtt
     6661 ttgtattgct ggtattcgat tttttggagg acttttgttt agtgagaagg cttgtcgctt
     6721 tcaaattgct atgatgccaa aattgttacc tgaaaatatg caatatccag ataaaataaa
     6781 agcgtattat atgacagata tgccacatgt aagaaaagaa acattctata atatgtatcg
     6841 tacttacatg atgaactata cacttaaaga gaatgttaaa aaaaccacag cacaagtaat
     6901 gtactggtat ggagaaaaag aaatgaagtg tgtcaaaaaa tctgcaaaac tgtttcagtc
     6961 ttatgtgccc tcttgtgaga tttatgaagc taagagctat aatcatgggt atttatcact
     7021 ttatcttcca aatgaatggt tggaaattgc agaaccattt ttccaaaagg aataaaggtg
     7081 ttaggtgatt attgtataat tattgctgtt tttttatata gtaaataaat taggtataaa
     7141 tataaaaaat tattttagtt aatatattag tgaaagctta ataggaaaat tataaataga
     7201 ttaaaggtag cacctatata aatagttgct acctttttct gtttgtaaat aaatgataga
     7261 taagaaggtt tactgacaaa tcactgacta aacccaattt tcttacattg aaagccttaa
     7321 ttttacttgt tttaaataaa tttacaattt cttgttataa aatactaaat tttgttaaca
     7381 attataatta gcatttaatt tatactggag gtttatatga ttagtgtaag aacagattta
     7441 gctttagaag ctagtgaaat gtgtgaaaag tctcaagaag gaagtagtat tcctggtgta
     7501 aaaatagaaa ctaaagaatt agaaaattgc attgtaacta aagttgaagt aatagacagg
     7561 caaggcgcag agataatgaa taaagatata ggaaagtata taactctgga aagtaatctt
     7621 atgaagtttg atgatgatga gtcaagagaa gaaatgataa gttatttaaa agaggagtta
     7681 gtagatatat ttggccaaga caaaaataaa aaaaccctgg taattggtct tggaaataga
     7741 aatattactt ctgatgcgtt aggaccaaag agtgtatcaa aaacacttgt aactagacat
     7801 ctttttaaaa attataataa agactatgat gatgatttca ctgaggtatc agctttaagc
     7861 ccaggagtta tgggtgttac tggaatagaa actagtgaaa tagtaaaatc attggttgag
     7921 aaggttaagc cagatagagt agtagcaata gatgcattgg cttcaagaaa aatggaaaga
     7981 gtaaactcta ctatacagat atcaacagca ggaatatcac ctggtggagg tgttggcaat
     8041 actagaaaat ctctaactaa agaaacttta ggcgtggatg ttattgcaat aggcgttcca
     8101 acggtggttg atgcagcaac tcttacaata gatgtcttag atatggcaat agacaattta
     8161 atagctcaat cagaagaaac agaaagtttt tatgaaatgt tgaaaaaact taaagaagaa
     8221 gaaaaatatc atctaataaa agattcgtta gacccatatg acaagaactt aatagtaaca
     8281 ccaaaggata tagatgatac aatcgaaaat ctatctataa taataagtga aggcttaaat
     8341 aggtctttac atccaggtag attggtataa aataaggagg agcaattatg tttaaaaaat
     8401 gcattaaagt agtaaccttg acttttatat tagtatgcat tttaccagga aaatcattag
     8461 ctttgaatca agatgatttt ttaaagtttt tagtaaattc atcttatcca gaagctaaag
     8521 tcgaaggaaa tgatacagaa aataaaaaga ataataaaaa taaagaaaca agtaaggaaa
     8581 ataaggaaga aagtaaagaa ggaaacacta aatctaaaga tgcaagtaaa gttgataata
     8641 aaaaagagag tgaaaaagaa tatataaaac tttatgttgg taaagaaaat gttccagata
     8701 ttgagtcaaa aaattcagac acaactgaaa ctaacacaac atctagttca gattataagg
     8761 atgatttaag agtaaccaaa gaaaatccaa gaattttgat atatcatact catggatgtg
     8821 agacttattc aaattcacct gatggaaatt atcattcaag agataagaaa aattcagtaa
     8881 tggaagtagg aagtgcatta actagtgctt tagatagcaa aggatggggt gtagtccata
     8941 ctactaaata ccatgactat ccatcttata ataactctta tgcaagtagc ttaaaaacaa
     9001 tacaaagtat attacctaaa tataactcag tggatatagc gatagactta catagagatg
     9061 ctagggattt aactaatcca gccactaagg aaaaagacca tttaaaatat acaactatga
     9121 taaatggaga gagagtatca aagttcttct ttgttgtagg aggtaaaaat acaaatagaa
     9181 aacaacttag agctttagca gaagatataa ctgcttttgc tgagaaaaag tatcctggtc
     9241 tagtatctcc aatagtagaa aaagactatg ctagattcaa tcagtttgca gttaagaatc
     9301 atatgttagt agaaataggg aataacgcaa caagtgtaga agaatctaag gctactacaa
     9361 agtatttagc cgagattttg gatgaatatt ttaaacaaaa aaattagagc tttaagttat
     9421 aattaggagc atgctaaatg agccgattag aaaaaaatat agaaagtaaa agtaaactaa
     9481 gaaaatacaa gtatattatg agaatcttat ttttgattac tatgattata tgtacatcag
     9541 tttgtgtatt tatagtggac agtaatgcaa aaagtatgct aggaatgaaa caatatgatt
     9601 ttccaagtat taaatttgat ataacaaaat ttgattttga cataccaaat tttgatatac
     9661 atgaaatcat aaaaaaattt aataagtagt aataagtgaa taaggtttat tgattaaaat
     9721 aagccttatt ttagttatat atttttaatg tataaaataa aaattcatta actgtatttt
     9781 ataggattta ctttaagttt atgatattat ataatattta gtgttagact tgataatcca
     9841 catataatgt ggataatttt gtttagtgcc aattagttta tattcaaaaa ttttaaattt
     9901 ggtatataaa gagtttttag ataatgtaaa ataataacta taagaataat caagaggagg
     9961 gaattttaag gtggacaata aacaaagtag aactagaaat tttagtataa ttgcacatat
    10021 agaccatgga aagtctacct tagctgatag attaatacaa caaactgggc ttgttagtga
    10081 aagagacatg aaaagtcaat tacttgacaa tatggacctt gaaagagaaa gaggaatcac
    10141 tataaagctt caaaacataa gattaatgta taaagcgaag gatggaaatg aatattattt
    10201 aaatcttata gatacacctg gacatgtaga ctttaactat gaggtatcaa gaagtttagc
    10261 tgcatgtgaa ggagcactat tagtagttga tgcagctcaa ggtgttgagg cacaaacttt
    10321 agccaatgtt tatcttgcta tagaccaaga tttagaaata ttaccaataa taaataaaat
    10381 agatttacca agtgcaagac cagaggaagt aaaaaatgaa atagaagatt taatagggct
    10441 tgattcaagt gaagctcctc ttatttcagc taaaactggt ttaaacatag aagatgtttt
    10501 agaagatatt gtaaaaaatg ttcctccacc taaaggagat aatgaagctc cattaaaggc
    10561 attaatattc gattcttact atgatgctta caaaggtgtt gtagcttatg ttagagtatt
    10621 tgaaggaact gttaaaaagg gtatgacaat aaaaatgatg aataccaata aaaagtttga
    10681 ggtaactgaa gttggtgtta tggctccagg tcaaactgaa cttagtgaat tatcagcagg
    10741 tgatgttggt tatattgctg ctagtataaa agatataaga agttgtcgtg ttggtgatac
    10801 aataacagat tcaaataatc ctacagaaga acctttacca ggatacaaaa aagctactcc
    10861 aatggtatat tgtggtatat atccaggaga aggagaaaag tatgagaatg ttagagatgc
    10921 tcttgaaaag cttcaagtaa atgatgctgc acttgaatat gaagctgaga cttcagcagc
    10981 actaggattt ggttttagat gtggtttctt aggtctttta catatggaga taatgcaaga
    11041 aagacttgag agagaattta accttgatat aattactaca gctccatctg ttatatatag
    11101 agttacaaaa atggatggag aggttgtaat gatacaaaat cctgcaaact taccagaacc
    11161 atctgagata aagatgatag aagagcctat agtaaaagga gatataatag ttcctaaaga
    11221 ctatgtgggt gttgttatgg agctttgcca ggaaagacgt ggaaatatgt taaatatgga
    11281 atatatagat gatagaagag taatgcttca ctatgacctt cctctcaatg aagttgttta
    11341 cgatttcttt gatgctttaa aatcaagaac tagaggttat ggttctcttg attatgaggt
    11401 taaaggttat gtagcatcta cacttgtaaa acttgatata ttaatcaata aagagcaagt
    11461 ggatgcactt agttttattg tccatgagac acgtgctttc cctagaggaa aggcaatgtg
    11521 tgagaaatta aaaggagaaa ttccaagaca tcagtttgct ataccaatac aagctgctgt
    11581 tggtaataag gttattgcaa gagaaacaat aagcgctcta agaaaagatg ttcttgctaa
    11641 atgttatggt ggagatatat ctcgtaagaa gaaacttctt gaaaaacaaa aagaaggtaa
    11701 gaagcgtatg agacaaattg gttctgttga agttcctcaa aaagcattta tgtctgtgct
    11761 taaattagat gagtaaatcc ttataaattt agataaagat atttaaaagc tagagtgatt
    11821 ttagaattat ttctaaatta gtctagcttt tttatggtat attttaagta aactcataga
    11881 gaatataagt aagaatatta aagaagaata aaaaggtgat atttatgatt aatatagaaa
    11941 ttcctaaaaa agtagactat ataattaaag aattagaaaa gaatggttat gaagcttata
    12001 tagttggagg atgtgttaga gattgtttat tagaaagagt tccaaacgat tgggatataa
    12061 caactagtgc tagaccagaa gtggtagtag aattatttga aaaaacaatt ccaactggta
    12121 tacaacatgg gactgtaaca gttatgattg aacatgaacc atttgaagtg acgacttata
    12181 gaattgatgg aaattatagt gatggtagac atccagattc aatagaattt acaaataaca
    12241 tagttaagga cttgtcaaga agagatttta ctatcaattc aattgcatac aattcaaaga
    12301 caggattagt cgacccattt aatggctatg aagatataca aaataagtat atacgttgtg
    12361 ttggaaatcc agtagataga tttgaagaag atgcacttag aatgcttaga gcagttagat
    12421 tttcagcaca actcaatttt aaaatagctg aaggtactaa gcaaagtatt cataaaaaag
    12481 cagatttgat aaaaaatgtt tctattgaaa gaatccagac agagtttaat aaaatattag
    12541 tatctgattc atctaaatta aacttattaa aatcaacagg tttgttgaaa tttataattc
    12601 ctgaaatatg tgaattagaa gatgttactc aacacaatcc atatcacatc tatgatgtac
    12661 aaaaacatac tttaatagct acagaagtaa ttgaagatga actgtattta aaacttacaa
    12721 tgttgtttca tgatttaggt aaaaaagtaa ctaaaacaac tgataaaaat ggtgttgacc
    12781 atttttatac tcatagtaga gaatctgtaa agattgcaaa gaagattttg aaaagactta
    12841 agtatgataa ttatactatt aataaagttt taatattaat acaatatcat gattatagaa
    12901 tagaacctaa aaggaagata attaaaaagt tattaaataa acttgaagat gttgaattat
    12961 ttgaagattt aataaaagtt aattgggctg atacacttgc aaaaaatcca aagtatgcaa
    13021 aacaaaagat attaaatctt attgagtgtg aaaaagaatt t
//
LOCUS       DAYAKB010000092        13046 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.092, whole genome shotgun sequence.
ACCESSION   DAYAKB010000092 DAYAKB010000000
VERSION     DAYAKB010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13046
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.092"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..1056)
                     /locus_tag="ACGI3L_003177"
     CDS             complement(<1..1056)
                     /locus_tag="ACGI3L_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFG9198873.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGAIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQ"
     gene            complement(1392..2378)
                     /locus_tag="ACGI3L_003178"
     CDS             complement(1392..2378)
                     /locus_tag="ACGI3L_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9198874.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            complement(2762..4516)
                     /locus_tag="ACGI3L_003179"
     CDS             complement(2762..4516)
                     /locus_tag="ACGI3L_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HFG9198875.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLIMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTESLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(4734..5624)
                     /locus_tag="ACGI3L_003180"
     CDS             complement(4734..5624)
                     /locus_tag="ACGI3L_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9198876.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            5773..6633
                     /locus_tag="ACGI3L_003181"
     CDS             5773..6633
                     /locus_tag="ACGI3L_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9198877.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            7089..7655
                     /locus_tag="ACGI3L_003182"
     CDS             7089..7655
                     /locus_tag="ACGI3L_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9198878.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQINNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            7695..8276
                     /locus_tag="ACGI3L_003183"
     CDS             7695..8276
                     /locus_tag="ACGI3L_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9198879.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(8333..9250)
                     /locus_tag="ACGI3L_003184"
     CDS             complement(8333..9250)
                     /locus_tag="ACGI3L_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9198880.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            9380..11011
                     /locus_tag="ACGI3L_003185"
     CDS             9380..11011
                     /locus_tag="ACGI3L_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9198881.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            11014..11961
                     /locus_tag="ACGI3L_003186"
     CDS             11014..11961
                     /locus_tag="ACGI3L_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9198882.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLANTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(12246..12509)
                     /locus_tag="ACGI3L_003187"
     CDS             complement(12246..12509)
                     /locus_tag="ACGI3L_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HFG9198883.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(12608..12853)
                     /locus_tag="ACGI3L_003188"
     CDS             complement(12608..12853)
                     /locus_tag="ACGI3L_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198884.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         4409 a         1918 c         1676 g         5043 t
ORIGIN      
        1 ttgcccactt gtttcatcat atcttaattt aattaattca tctactggca tttgcaatag
       61 cttattattt tttatattta attttcttgg aacagttaga caatgtgccc atttgttttt
      121 atctgtaggg tataaaactt ctcccattcc agcccatgca aatagtatta tttgtgagtc
      181 ctttataaat gtttgtggag catagaaatc aaatcctttt tccagttctt tcattgtatc
      241 tatttcaaat gttaaattat ctaaatccat attaccaata gcatatacta cattatatat
      301 attttgataa tcaaatcctt taggttctac tccttgtggt gaaaatatta atatatcttt
      361 ttcatctata ttaatataat ctggacattc ccacatgtaa ccaaaatctt catctatatt
      421 ttttacattt aattctcctt taaaattcca atctatagag tttttagatt catatactat
      481 tatagctcct tttttatcac ttgtttgtgc tccaagtaac ataaagtatt tatcctttct
      541 tttaaatact tttgggtctc ttacatgtcc tgtatatcct tttggtattt cacttactat
      601 tggattattt tcatatttag ttattttacc atccttgttc attatagcta agttttgata
      661 tgcatatcta tcttctgcac tatattttat attccctgta taatacatat gcaattttcc
      721 atctacctct atcgcattac ctgaatatgc tccatgagat tcataacttt cgattggtat
      781 taatgctaca tcttctctat tccagtttac aaaatcatca gaacttacat aagcccaatg
      841 cttcattcca tgagttgcat catatggata ccattgataa aatacatgat acttaccatt
      901 ataatatgct aatccatttg ggtcattaag tagtccatgt tgtggatgta tatgaaatag
      961 tggtttatat ttatcattta aagatatatt tcttaattta tttaattctt cttttgtcga
     1021 ttctaatatg gttctatatt taggctcttt gtacatattt ttattccttt tcttttataa
     1081 ttttatattt gctttattat tgctatctaa aacaattctt agtcttatta cacaatgtgc
     1141 tacatctttt atattttgtt tattcctatg tactctaata attactttga tactttgtta
     1201 caatcagtta tttttgcact cattttgcta ttctatcggt ttaattaaac cggtttcgaa
     1261 accggtttaa ttaaagatta gcataaattt atttcagatg caatatttct ttcaaaaaag
     1321 ttttcctaat ttttagaatt atagtttttt tagtaaaaaa atacacatta ctaatatatg
     1381 taatgtgtat cttaattttt atttattgta ctttcacctt ctattaattc aaatttaatc
     1441 tcctttaata gtggttcttt tctttcttgt attaaattta ctatcgtatt tgctgctact
     1501 ttacctgcat ttttattttc aaactttatt gttgtaagtt tagggcttat aatagacaat
     1561 acatcatatc ccccaaatcc agctacagat atatcttgtg gtatattttt acctctctta
     1621 ttgatttctt tcattgttgc tattgctata ttatcagttg cacatattat tatatctgga
     1681 ttttcacttt ctagcatttc tccacttctt tgtatagacg tttcttggtc aaagtcagta
     1741 taaaatactt ttgcatcata ccctttatct tttaacccat taagtactcc attttttcta
     1801 tttaaaccaa ctgatatatc actttcatca acacctaaat atacaatgtt tttgtaacct
     1861 ttattagcaa tatattgacc cattttatat cctgctccat aatcatcatt cactatgcta
     1921 ttgataccat caactttttg tccaactaca actatcggta tatctaactt ttcaatttca
     1981 ttcttatgtt ctttagttat ttcggtacca attagtatta ttccatcaac ttttagacta
     2041 gctaattttg atatactatc tatttctgac cttatttttc tattagtatt aataattagt
     2101 gatgtatatt ttaattcttt gagttcttca tctattgcca tcataatttt agattttaca
     2161 aaagaatcta aacacggtgt tataatacca ataaagtatg tttttttagc tctcaaactt
     2221 tgagcaaatg cattcggctc atatccatat tcatctatta ttgtctttat tttctcttta
     2281 gtagaatcac tgatatcttt attatttaga tatcttgata cagtactttt agatactcct
     2341 gccaagttag caatatcatt tattgttatt tttttcatag gttatcacct tctacatttg
     2401 atatatttta ttacattata ttatatattt aaaataaaat atagttattt gtccagtcaa
     2461 tactttttat atactacttg tactatccat tccacatcca aataattgag tctttaacat
     2521 taaattaatt gtaattttca ttttttgttg ttatatttaa tttcaatttt atctactatg
     2581 aattgataaa tactctaatt tatttataat ataaaaataa ggctatgatt tttacaacca
     2641 tagccttatc gataaacact taattatcac ttaaaaaata attttttatt taaagaatat
     2701 atataaatat tttaaaattc tataattttt aaaactatat aaactttatt ttcatatgtt
     2761 tttattctcc aattgatata ttatttatgc cattattttt aacttcaata attggttgtc
     2821 catttcctaa aatataatct ttagaccaac cttctggcaa tttatttatc ccatttccaa
     2881 ttaacttcaa gtgtaaattt gatggttctt ttttcagatt taatttaaat attccatcaa
     2941 aggtaccttt attatcgctt ccaaataaac ttatattgcc atttatattc gtagctgtta
     3001 catttacaat tccattgttt gctctaaatt ttatttcaga tgatatagtt tcagctgtta
     3061 cacctgaaat cccactatta gtatttatat tgaaaggatt tgttacattg ttatcaacaa
     3121 tgttagcaat cccgtcattg acatcaacag tagctcctcc tttaatatta taaagttcta
     3181 ctgaaccact ttcaacatct actttaaaat tagaatacat tttatcggga actccaattt
     3241 ttatcacatt taccatccta tctttatttg catttatcat attgtcgcca ttcatatctt
     3301 gcaaatcact atctttctta tctatttttt tcttagcact tacaactagc tttccatttt
     3361 ttatattatt agaagaattt tctttatata cagaaaaagt acaatttttt tcattagtta
     3421 cacttacgta atcaaactca aatttattgg tattcgtctt ttcaacaacc acacctaaat
     3481 tatctgattc tataagtatt tcagaaactt catttccttc aactgaagtt aagtgtttta
     3541 aaatatttgg agtcatatcc atattattat atttaatcat atctaaacac tgtttatata
     3601 tattggcatc aatacctcca acttttgtta tacttttagc tccttttaaa atacctttat
     3661 tacttccatc agcaactaaa acgattggtt tttctttggc taaaggagat aatgttagtg
     3721 catctactaa ttgatatcca tttgttatat aaaaatctgt cgctccatta taaaactttt
     3781 ccattacctt tttattggtc tcaaatctat catttcctcc gattctagtt gctttagttt
     3841 catttactaa atcctcattt atcgcagatt tgccacctat agcgtaaaca tttaaacttt
     3901 cagtcttaaa tggaactgat ttcccatctg taagtattat agctccttta ttttttgcaa
     3961 ctacaggtgc tatactcata gcatcagcct ctcctacaaa tccatttgta agcattacct
     4021 cttttacact acttacttca tttatttttt tagctacatt ataactagtt tcaattctat
     4081 tgttaccatt tattctttcc acttgaatac cttttctttt tatatctttt tctactgaat
     4141 tttcaatagt attataacca ccaattatat atactttttt tacaacattt aaactcttat
     4201 tatctagtct atttaaagta gcttttggta tttcactttt tttagtcaaa agtattggtg
     4261 cgttaatagc tccagctaat ccacttgatg aaagcccatc agataaattt ttatctccat
     4321 taactaatat tacagtatca taagtttgtc tatctgctat aagtcctgct gtttcatatc
     4381 tatcaattcc tattattgaa tcttctttaa tctgtgcatt tgcagttaaa ttattaaaaa
     4441 gaaacataat caaaactaaa attaatatac ttagtttttt actgaatttt ttgaattttt
     4501 tattcataat atacactatt cctcctgtaa attaaggtct ttaatttgct tataaattat
     4561 ccccttattt acaaataata acataatatt atagtaacgt atatattacc ttaaaattat
     4621 cagtaacttt atatcaatca tcttagctta tttatataaa tttttttata ttacttttca
     4681 aataacagtc atactaaaac aatttcatca tataatttga aaattattac tatttacaca
     4741 gcttttatca tcatcttacc accatcaaat atatattcaa ccatattatt ctcatataaa
     4801 taagttatat aagaacgtat tgtacttcca accaacacat attgattagc atcaagcttg
     4861 acattgtaca aatcacacat tttttcaata acttcatcaa tcataactgg ctcataacaa
     4921 acctttttaa tattatctat tatttcttcc atcttcttct tattaatatt aattaaactt
     4981 tttatatctg tagttttgac agagtgactt ggaacaaaga aatcagcctc taacattctc
     5041 aatttttcta gtgtcttaaa ctgtgaatct atatccagta ggaagaaaaa atgatattta
     5101 gtaattatat tctctggtgt aagactatct gcaacaaaca aaacattatc tggagttcta
     5161 acaccaatca tttcaaaata atgacctgga agagaaatcg cttcaagttc tgtatctaca
     5221 attttgccat ttgaagggat aatataatca acttcacttt cctttgctaa taaaaattta
     5281 ttcttcagtg ctttacttgg atagccacca tataaaaatg ctgattctaa tattggattt
     5341 tctgtaaaat atccttcaat tttagtcgta gcaatcttgc attttgtttg attcttcaaa
     5401 tatgcatttc ctcctatatg gtctgcattt gaatgagtgt ttattattaa tttaggattt
     5461 aaattatgtt cttctaataa tcttaaaact tgtctagctg tatccttatt atttccactg
     5521 tcaattaaaa ttgcatcctt accatctacg tatacaccta ctattgtagg gagtggaata
     5581 taatatgtat ttccttttat atgttctaga gttaatttag ccattttata acctcccttt
     5641 aaatttactt ttaattatag cattaatttt ctgaaaattc caatcaaatt gtttttataa
     5701 tatattttta tttcttttat taaaaattgg aaaaactata taatatatat tataatctat
     5761 atataaggag tgatgttatt gaaaaaagat agaataactt tttcagaaat tttaatatta
     5821 attgtaggct gtatattaat ggccatttct cttaacttat tttttaatcc acatgcaatc
     5881 gctgctggtg gtataacagg acttggagtt gttttaaatt cattattcgg tgtagaactt
     5941 tggattgtca atttactttt aaatgttcca ttattcatat ttgcttacaa aatactttca
     6001 aaaaaagatt gttttaaaac ggttttagga ataatttttc ttaccatagc acttaagctt
     6061 actgcaaata tggctacatt agatataaca aatgatatgt atcttgcaat tatatctggt
     6121 tctattttaa tgggagttgg tcaaggactt atttttagaa taaatggctc tacaggtgga
     6181 actgatttaa tggcactcct actaaataaa tattttccta catttagtat acctgtttta
     6241 atgggtattg tagactgcgt tgtagttgtt ttatcaggta tagtaaatag acaggttgaa
     6301 attgcacttt attcaactgt ggctttatac attttagtaa aagttagtga cttgcttatt
     6361 gaaggattta attattccaa atcattcact attatatctg acctttcaaa agatataagt
     6421 aaaaaaataa tggaagattt agatagaggt gcaactattc taaaaggaga aggtgcatat
     6481 actggagaaa ataaaaatgt acttttagta gtagttgaaa agaaagaagt tgtcgaattg
     6541 aaaaaattag taaaaaatgt cgaccctaat gcttttatta taattacaga tatacatgaa
     6601 gctttaggta atggatttaa aaaaatagaa taactaacaa ataaatagca agtataatta
     6661 acatatacaa attcaacttt ttatatgtta tattatactt gctatttata tattatactt
     6721 gctatttata tattataatt gttgttttta agataaaaat taaatgtatc aattattgtt
     6781 ttatacaagt atttccaaat ccgttctcat ttagatagta tgcttagaaa ttttagaatt
     6841 attgagtcta actttattac ttactttact ttataacaat caaatacaaa tttaaatatt
     6901 ataaaactac aaaataattt aaagcatata atgtcaatat gtttaaatta taaaatattc
     6961 atgtagttat ataataaata atttataaat atagccaact tagcctaaat acgtatataa
     7021 tatagctaat atggttctta tacttgatac catcaataaa actaaaaata taaaaaggag
     7081 aacttaaaat gagtgttagt ttacaaaaag gacaaagagt tagcttagta aaagataata
     7141 atcctgtaaa aaatctagta gtaggcttag gatgggatat gaataaattg ggtaaaaaaa
     7201 attatgacct agatgcattt gcaatagcat tgactaacca agataaaatg aatgttagag
     7261 gtgacttggt ttattttgga aatcttaaac acccttctaa agctattata cacactggag
     7321 ataacttaac tggaaaaggt gaaggtgatg atgaacaaat aattgttaat ttagaagaca
     7381 tacctgaata tgtacataaa atagtttttg gagtttctat atacaaagct aaaaaaagag
     7441 accaggattt tggtcaaata aacaactctt ttataagatt aattgattca aattccaagc
     7501 aagaattatt taaatataat cttcaagaag acttttctgg taaagtaaca gttttggcag
     7561 gagaaattta tcgtagaaat gaagaatgga aatttaatgc tttaggaatt ggtcaaaatg
     7621 aagagcttcg tgaattaatt aatacatata agtaataatt acaataaaaa atttataatg
     7681 aggagttggt ttaaatgggt ataactttag caaaaggaca aaaagtaagt ttaacaaaaa
     7741 gtaaccctgg tctaaaaaaa gtaatagtag gactaggatg ggatattaat aaatatgatg
     7801 gtggctttga tttcgattta gatgcctctg catttttaac tggaactgat ggaaaagtaa
     7861 cgaatgatgg agactttata ttctataata atttaaaaca cgcttctgga gctgttgaat
     7921 atatgggtga taatagaaca ggtgttggtg atggtgatga tgaacaaata aatgtagact
     7981 tatctaaaat acctcaaaat attgctaaaa tatcatttag tgttactata aatgaagcaa
     8041 ttacaagaag acaaaatttc ggacaagttg aaaattcata tataagaata tataatgaag
     8101 aaactaatga ggaacttatt aaatatgaat tgggtgaaga ttttagcata gaaacagcaa
     8161 tagttgtggc agaactatat agacataatg gagagtggaa atttaatgct ttaggttctg
     8221 gatttgagga tggacttgca ggattgtgta aaaattttgg cgttaatata ggctaatata
     8281 tctaaataaa aataagagta tattgatata ctcttatttt tatttagata tattataaac
     8341 tgtttacact tctactcttc tttctcgctt gttttttccc atattctact gaaatatcaa
     8401 aaaatgctga aatattttct gtaaaaaact tgcttctatg atatgcaata tcaaatgtcc
     8461 tatgtaaatt aataccttca atatcacaag cccacaaaag atgctttttt aaataatcct
     8521 caataagtaa ttcggatata actgcaatgc caaaattatc tacaactgct cttaatatag
     8581 cttcagagtt ataacatgac catctaatat tcattgggat ttttaattct tttaattgct
     8641 tttctaattg tgctcttgta ccacttccca attcacgcat aattaatggt tgatttgaaa
     8701 gttctgaaac ttttatagag tctcttttat aaaactcatg cttgtgtgaa catataagta
     8761 caagattatc attaataatg ctttttgtaa caatatctgg gtgcttaatt tttccttcta
     8821 caatcgcaat atctaattca ctattaagta atttttttgc aatcagtctt gtatcttcta
     8881 caaatacttc aggttctata agaggattta ccttgtataa ttctaacatt attggactta
     8941 ttacacatgt accaacagtt actgttgccc caactcttat acggatattt tttgcacaat
     9001 gcttcataca atcattcatt tcttcattta cagctaaaag atgcctccca tatccaagaa
     9061 gttttttccc tgcctcagtt aaatataatt tttttgaaat tctatcaaat agcttaacac
     9121 catactcttt ttctatttct gaaatagctt ggctaactga tgactgggta atatacatat
     9181 ttcttgctac ttcactcatt ttaccacatt cagcaacctt aacaaagatt tcaagactac
     9241 gaattgtcat attatcacaa ccttagcaaa cattagtaaa tgcttatgat tttattaata
     9301 ttttagtatt ttacaaatat attgtcaaga agtataattt tattatagag ttataaagta
     9361 gattggagtg tgatatattg tgaaagtatt aattataggt ggagttgctg ctggaacaaa
     9421 aactgctgca aaaataaaac gtgaaatggg tgataattgc tctgttacaa tactaaataa
     9481 aggtgatgat atttcttatg caggttgtgg tcttccatat tacgttggta agataattga
     9541 agataaatca tctttaatcg taaatacacc tgaaagtttt tctaaactaa caggagcaga
     9601 agttcgttgt ggagttgaag ttacatctat tgatagaaat gcaaaacaag taactttgaa
     9661 aacgctttca acaggagaaa aagaaaatct aagctatgac aaacttgtaa ttgctacagg
     9721 ggcagaccca ataaaaccac caatacctgg aatagattta cctggagtat tctttatgcg
     9781 tactccaaat gatgctataa aactaagaga ttctattgaa aacggtatta agagagctgt
     9841 tgttattggt ggaggtttca ttggtcttga aattgctgaa aatctttctg caatgggtat
     9901 acgtgtaagt gttgttgata tggctgaaca tgttatgcct ggatttgata ctgattttgc
     9961 tgaatacgtt gaaaatcata tggctgataa aggcataatg atttttacag gtgaccaggt
    10021 tgtaggtatt gaaggtgaaa ataaagttga aaaacttcgt actaaaaata gagctattaa
    10081 aacagattta gtggttatgt cagttggaat ccgtcctaac acaggttttc taaaagacac
    10141 aggtttagaa tttgccccta ataatacaat tattgcagat gaatatatgc ttacaaatga
    10201 caaagatata tatgtagttg gagactgtgc ttttgtaaaa aattctttaa caaataaacc
    10261 tacatggtca cctatggggt catctgcaaa tcatgagggt agaatttgcg cacaaaatat
    10321 atctggaaaa tctaaaactt acaatggtgt tcttggaaca acagtagtaa aattacctga
    10381 gctcaatgca ggaaaaacag gtctaagtaa agaaatagct gaaaaagaag gttataatgt
    10441 ttgctctgta accatagcta ctgatgataa agctcattat tatccaggtg catctaattt
    10501 tattataaga atggttgctg aaaaaaatac tagaaaatta ttaggtgttc aagttatggg
    10561 acctggagcg gttgataaaa tagtagatat cgctgctact gcaataactt taggcgctga
    10621 cctttattca ttagaaagta tggaccttgc atatgcacca cctttttcaa cagctattca
    10681 cccttttgta gtggcagtaa atgttttaca aaataaactt aatggagaac ttgatagtgt
    10741 tttacttgac gaaattgagg attttgacag ttggactaaa cttgatgttt caaaagctcc
    10801 ttctattcct agtttacgtt atattcctgt tggtgaaatt aatggagaaa ttgaaggtct
    10861 tgctaaggat gaaaaaattc ttcttatatg tgctaaaggt aaaaatagct atatggcgca
    10921 aaatcgctta agacgctttg gctatacaaa tacgaaagtt cttgaaggtg gaatactatt
    10981 ttatccaaat cttaaggtaa tggaggagta aatatgagta atgttacagc agaacaaaaa
    11041 aaggaagtaa aaggtagagg ttttctacca agcagggatg gagaacattt tgcagcacgt
    11101 ataataactg taaatggtgt aataaatgca tcacaagcaa aaaaaattgc agaagctgct
    11161 gaaaaattcg gaaacggtca gttagcattt actactagac taacagtaga attacctggt
    11221 gtaaaatttg aagatattga agctctaagt gaatttattg ctagcgaaaa tctaataaca
    11281 ggtggaactg gatcaagggt tcgtcctgtt gtggcttgta aaggtactgt ttgtgttcat
    11341 ggtctagcta atacacaggc acttgctgct gaaatacatg aagaatttta caaaaattgg
    11401 tatgatgtaa aactacctca taagttcaaa attggtgttg gtggatgccc taataactgt
    11461 attaaacctg acctaaacga tcttggaatt gttggtcaac gtgtacctga ctatgattca
    11521 gagctttgtg ttggttgtaa aaaatgtgct gttgtagagg tctgtcctgt taaagcagct
    11581 aaattaacag ataaaggtaa acttgaaata gatagtaatc tatgtaataa ctgtggtaag
    11641 tgtatagaaa gttgtaattt tgatagtatt gaagaaaaag aatctggtta taaagtctat
    11701 ataggaggga aatggggaaa atcagttcgt cctggaacac agattgatag attattttca
    11761 aaagaggaac ttatgacttt aattgaaaaa gcaattcttt tatttagaga acagggtaac
    11821 acaggtgaac gttttggaat aactatcgat agaatcggtg ctgataaatt tatagaaatg
    11881 cttttatcag atgaagtttt ggaaagaaaa gaagagatac tagaggctct tttacacctt
    11941 acaggtggag ctgtatgcta acaataaata ttttaattgt acagataacc tatggaaaaa
    12001 attttagtta agaataatta aaattctata tatgatatat gataaatgag gctatctcaa
    12061 aacacagata cgcctctttt tcattgttga aatgataaag tatatttgag ttcatataaa
    12121 aaagagtgtc tcatgaatta taaaattcat tttgaggcac ccacattatt ttataataat
    12181 tgcttattaa ttttatttta actatataaa atgtacaaaa attaagaata tccaatattc
    12241 taaaattaat tttgaattgt attgattgaa aagtttacta ttccactatt tccatcttga
    12301 tttactacta gataccatgt tccagtatta ggaactctca ttctacatgg atttttcttt
    12361 gcaaatccac catagtaatc ataatttctt tgatttttaa atttcacata atttatatgg
    12421 tctaacaata ttacattggc ttgtttctct aaatttacct ctacaatatc cccttttttt
    12481 aagttcatct tactataact atattccatt gaattactcc tccagtatcg aataatcttt
    12541 gttatttact catctcaaat atgtaaaaat tcatttaaaa tattacaaat actatataat
    12601 tagactatta tccagtttta accttattta ctacaatcca aaggttatta aaaatattat
    12661 tggcaacaac ttctccatcc catacaactc tttcttcttt attttctaat aaagcatagt
    12721 acccagagtc agaactttca tctttataga ctgtaacata aaactcttca tcactatatt
    12781 caggtatatt tttaaagtct tcagatattt tacatgttaa tatataacct tctaattctt
    12841 catctataaa caaagcaatt cctccaatct ctatattttt actaattata ccatattatg
    12901 tcataaactt tttattttat tacaaatttc tattttttct ttactttata aataaattat
    12961 ataaatttta acttttaaac tttatattat actaattaat tcttttgttt tcctatatat
    13021 ttctttatat tttataaatt tagcca
//
LOCUS       DAYAKB010000093        12827 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.093, whole genome shotgun sequence.
ACCESSION   DAYAKB010000093 DAYAKB010000000
VERSION     DAYAKB010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12827
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.093"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(291..1541)
                     /locus_tag="ACGI3L_003189"
     CDS             complement(291..1541)
                     /locus_tag="ACGI3L_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 family protein"
                     /protein_id="HFG9198885.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1573..2514)
                     /locus_tag="ACGI3L_003190"
     CDS             complement(1573..2514)
                     /locus_tag="ACGI3L_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HFG9198886.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2754..3830)
                     /locus_tag="ACGI3L_003191"
     CDS             complement(2754..3830)
                     /locus_tag="ACGI3L_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HFG9198887.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4203..4718)
                     /locus_tag="ACGI3L_003192"
     CDS             complement(4203..4718)
                     /locus_tag="ACGI3L_003192"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HFG9198888.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5081..6151)
                     /gene="leuB"
                     /locus_tag="ACGI3L_003193"
     CDS             complement(5081..6151)
                     /gene="leuB"
                     /locus_tag="ACGI3L_003193"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HFG9198889.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6158..6649)
                     /gene="leuD"
                     /locus_tag="ACGI3L_003194"
     CDS             complement(6158..6649)
                     /gene="leuD"
                     /locus_tag="ACGI3L_003194"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HFG9198890.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6664..7941)
                     /gene="leuC"
                     /locus_tag="ACGI3L_003195"
     CDS             complement(6664..7941)
                     /gene="leuC"
                     /locus_tag="ACGI3L_003195"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HFG9198891.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7898..9640)
                     /gene="leuA"
                     /locus_tag="ACGI3L_003196"
     CDS             complement(7898..9640)
                     /gene="leuA"
                     /locus_tag="ACGI3L_003196"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HFG9198892.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTTQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9764..10010)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10158..10604)
                     /locus_tag="ACGI3L_003197"
     CDS             complement(10158..10604)
                     /locus_tag="ACGI3L_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198893.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10625..11344)
                     /locus_tag="ACGI3L_003198"
     CDS             complement(10625..11344)
                     /locus_tag="ACGI3L_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HFG9198894.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11462..12736)
                     /locus_tag="ACGI3L_003199"
     CDS             complement(11462..12736)
                     /locus_tag="ACGI3L_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HFG9198895.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNVKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
BASE COUNT         3892 a         2459 c         1307 g         5169 t
ORIGIN      
        1 tcaaaatcac tttttttatt aactttttta taattataat aaaaatatat aacagtacta
       61 ttataaatac acatttaaaa ccttataaat atacaaatac aattatatga attttcatcc
      121 tcaattatag catagaatat gactatctat atcctaaaat tatccatttc taaaaaaaag
      181 gtaactatta ttaagaatat caacttatag aatttatatt ccacatacga ttttcaatca
      241 aaaaaacaag ggctaaaaag tgaattgtgc actttttagc cctttattaa ttattcattt
      301 atttcatgta agaatagacc acatcttact ttaggttcaa accatgttga cttagctggc
      361 attatcttat ttgcatctgc tactcttatt aaatcttcaa tactagtagg atacattgca
      421 aatgctactt tcatatcttc attaactctt ttttctaatt cttcaagacc tctaattcca
      481 ccgataaaat caattctttt atctactcta ggattatcaa ttcctaaaat agcatcaata
      541 acatagtctt gtaatataga aatgtctaat gagtcaacag ggtcttctat ttctaataaa
      601 tttttatttg ctttcatttt ataccactta tcacctaggt acattccgaa agttcctttt
      661 ttgtcaggtt tatatttttc ttttccttct atttcttcta gttcaaaatt ttcttttatt
      721 ttatttataa attcttcctc gcttaaacca tttaagtctt tgataaccct attataatcc
      781 aaaaccatta aattctcatc tggtgcaatc attgctatga agtaattaaa ttcttctttt
      841 ccagtataat ttggattttt agctctcatt tctttggcta cattttctgc tgaagctgtc
      901 ctatgatgac catctgcaat gtatagataa tctaattttt caaatttatc tactaggtta
      961 tctattatat catcattatc aatcttccat actgtatgct ctatcttgtc atctgttatg
     1021 aaatcatata aaggttcatt attatccata aaatcattga ttatatcatc tatcaccctt
     1081 tgatgtttgt aagttacaag tatagttccc gtattagcat cacagtattt tatgtgttta
     1141 gttctatcaa tttccttttc tggtcgagtg tactcatgtt tttttattgt tccattcaag
     1201 ctttcatcaa ctgatataca tgctactata ccaacttgag ctctaccatc catgatttgt
     1261 ttatatatat atatacactc tttgtcatct tttactagaa tttcttgttt tcgaaactca
     1321 tctaaatttt ctcgcgcttt taaataaact ttttcatcat ataaatctat attttcatct
     1381 aaatcaattt ctgatttatc tatatgcaaa aatgaatatg gattcccttc tgcaattctt
     1441 ctagcttctt tactattcat aacatcgtaa ggaagtgctg ctactttatc tactatatat
     1501 ttatttggtc taatcgcctt aaatggttta atcgttgcca ttactaattt cctcctaatt
     1561 atacaaaata ttttataatg ctacccctat tagattgttg aagtcaagaa agaaatcttg
     1621 aatcacattt actatttcgt ctcctattct ttcttgagct tctactgtag atgccccaat
     1681 atgaggtgta ggagaaactc ttggatgatt tactaagtct aaatttaatg taggttcttg
     1741 ttcataaaca tctatagcag ctgctgataa tttaccttca tctaatgctt ttagtaaatc
     1801 tttttcatca actaaaccgc ctcttgcaca gtttattaaa taagcccctt tcttcatctt
     1861 atttatttct ttttcagtta ttactgcccc cttattctta tcaaatggta tgtgtaaaga
     1921 taagaaatct gcattttcta aaacttcttc catatcacag aatttataat tgttaaagcc
     1981 ttgcgcctca cccattatgt cagtatatat aacattcata cctaataatt ctgctctctt
     2041 tgcaacttct tttgcaattc ttccaaaacc tataagtcca agtgtctttc cattaatttc
     2101 tgtaccttta tactttttct tctcccattt tccatctctc atagttacat ttgcagtatt
     2161 tatgaatctt gcaagaacaa ataattgacc tattgtaagc tctgcaacag atatactgct
     2221 tgcatttgga gtattcataa cttttatgcc attagcttga gcatatttaa catctatatt
     2281 atccagacct actccacctc ttactatcaa cttcaacttt ttaccctcta atgctttatc
     2341 tattacatct ttagtaactt tagtagctga acgtactaca agtacatcaa catctttaag
     2401 tttatctcct aaaacatctt tttcataaaa ctgctctatc acattaaaat ctaactctct
     2461 caattttctc gctgcttctt tctctattcc atcagtaact aatatattat acataacaaa
     2521 ctcctccaat ttttattcac ttaatttttc caatttttat tttttaaagt attttcatca
     2581 ataaaaaact ttacttaatt taactttctg tttatataat tttcaaaata tttttttatt
     2641 aaagtcatat caaatttttc tattgtttgt taaaaattta atatgtaatt tttataaaat
     2701 attatttatt atatattcta aatttatctt aaaacataca tatttttaca atattattta
     2761 ttaaaaccta atatatcatc aatattatct aataattctt gtacatcttc gacagtatag
     2821 tcacccatat gtgaaattct aaaagttttt tcttttaaat ctccatagcc atttgctatt
     2881 tggaatcctc gttcttgtaa ttttgaattt aaatttgata cactaatacc ttgagtattt
     2941 tctataacag taagtgtatt ggataagtga ttttcattgg taaaaatttg gaagtgtttt
     3001 ttagcccagt ttctaactaa gtttgccatg tcttcatgtc tgttgaatct gttatctagg
     3061 ccttcatcta atatattatc taattggaaa tctaaagcga acatgtgaga aagagatggt
     3121 gttgaagggt attggtagtt tttcttgatt aagtattcat acattgctaa caaatcaaga
     3181 tatactcctc taaaaggtac ttgcttagct ctatcgattg ctttttgaga aaatgtgcaa
     3241 atagacattc ctggtggtaa tcccagtgct ttttgtactg atgttataca aatatctatt
     3301 ccaatcttat caacctcgac ttttattcca ccggctgaac ttacagtatc tacacagtag
     3361 attacatcct catacttttt aacaacttct ccaatttctt ctattggatt tcttattcca
     3421 gttgaagttt cattgtgagt tacagttatt aaatcgtatt ctccggtaga aagcacctta
     3481 tcaaccattt ctggcgttgt tgcctctcct aattcaactt taaatatatc cgctgggaca
     3541 ttattagcca ctgccatttt gtaccatcta tcaccaaagg atccacagga aaatactgct
     3601 gcctttttgg atgtacagga acgaatggag ccttccatta aaccagttcc ggatgacgtg
     3661 gataaaagta tcgtgttgtt tgtatagaat agtttttgca tcttttcact tatactcttt
     3721 tggagcatag atgcatcttt tcctctatgt cctatcattg gtgtagccat cttttgcaag
     3781 acttcttctt taacatcaat aggaccagga ataaataatt tcttactcat tataattccc
     3841 ccctttttag tttgtaatat ggatagcgtt tttactgtcc ttatttttaa taactataat
     3901 atcaagctga attaactatg tcaacataaa atttattttt tatatataat ttattttata
     3961 tattttatga aaacattcat tttctacctt ttcataagtc tgaattttct gaattattcc
     4021 ctcaaaaaaa atatactttt tatctatata aattaatttt tttagtatgt aaattttacg
     4081 ctattacgat aaatcttttt agtataacta atttattttt atcttgtatt tttattgtat
     4141 ttttgaattt tattttttct aaatataaaa tttatgtttt aaaatataaa atttttattt
     4201 aatcaaagtt caatatattc cactttttct ttcgattctt caaaaaacca ttcttcatta
     4261 gaaaaatcac cttctgcaat ttgtccaata ggcattttca tatactttcc agttgctgtc
     4321 actgctatat ctccatttgg tagaattatt tctcctgtac cttcaaataa ttttctgttt
     4381 tctttagtta ttcttccaac aacttttata gtagcatctg ttggtactgg tttcttatat
     4441 ttcaactcta aagatactgt tactccccat atttggtcat catttatact tacagctctt
     4501 ccaatagtct catccaatat tgcagcagac atacctccat gaactctccc aggataactt
     4561 tgatgccaat cctttgtatt acaaattgat acaagctctc cattttcaag ttcataaaaa
     4621 tctgctttaa gtcctagctc attttgtgtt ccacaaacta aacaagattt actactattt
     4681 tgcttcttca aaactttata ctttgccaaa aaatccatct cctaaccgac attagtagtc
     4741 gcttaatatt aaataattct aaaatatatt atataatatt aataaaatcc ctgcaaactt
     4801 ctaataataa aaataggcta cttcaatatg ataagtttaa tttaaagtat tattttccaa
     4861 aaaataactt tatcaaaata gaaactcaaa gtagatataa acctcttttt cgttattaaa
     4921 atagtaaaaa tatatttgac ttaatataaa aaagagtgtc tcattaacta ataaagttta
     4981 ttttgagaca cccctcataa aacaaattat actacaatag atttttacta attctacaag
     5041 ttatatattt aaattatatt attcaaatta aactataatt ctaaatttca tttactatta
     5101 attcgcccat ttcccttgtt cctacaacat ttcccacacc attatagata tcaatagttc
     5161 tataaccttt attgagtaca ctttgtacag catcttcaat acacttagct tcttcttcta
     5221 agttaaaact atgtcttaac atcatgctta cagatagaat agtcgcaatt ggatttacaa
     5281 tatcttttcc agctatatca ggtgcacttc catgtattgg ttcatacata ccaaaactat
     5341 cttctctaag tgatgctgat ggtaacatac ctatagaacc cgtaatcata gatgcttcat
     5401 cagatattat atctccaaat atattattag tcactattac atcaaattgg ctagggtctt
     5461 ttacaacttg catagcagca ttatcaacat acatatgtga cagttctaca tcttcaaact
     5521 ctttagctaa gtcttccatt atacttctcc aaagtcttga actctcaagc acatttgcct
     5581 tatctacact tataagtttt ttatttctat ttctggctat ttcaaaagct ctcttaccaa
     5641 ttcttcttat ttcattttcg ttatatattt ctacatcata agcattttcg ataccatcaa
     5701 tgatttttct tccacgttct ccaaaataaa tgccccctgt taattccctt acaacaacaa
     5761 aatcaatgcc tttctcaact atatccgttc taagtggtga agcttctttt atactttcat
     5821 acattgtagc tggtcttaaa tttgcaaata aacccaatga ctctcttaat tttaaaagac
     5881 cagactctgg tcttttatct cccttacatt tatcccactt tggtcctcca acagcaccaa
     5941 gcaatacagc ttcgtttttt cgacaagttt caacagtttt attaggtaga ggttctccag
     6001 tttcatcaat cgcgcatcct ccagctaata catattcaca atcgaatcta tgattaaatt
     6061 tacaacaaat tttatttaga acctttatac cttcatctat aatttccggt ccaacaccat
     6121 caccttttat gactgctata ttacaattca tacttcacta ccccctattt gcttttattg
     6181 agttaattaa gccttcattt aatataatat tttgcataaa ctcaggaaat ggttctgctt
     6241 tatattcttt tccttttgtt atatttttta tcacacctgt agaaaaatct acttctatat
     6301 tatccccttc atctatgtta ttggcagctt cttcacattc aagtatagga agccctatat
     6361 ttatagagtt tctaaaaaat attctagcaa aagtagaagc aatcacacag gatactccac
     6421 tttcttttat tacaattggt gcatgttctc ttgatgaacc acaaccaaag tttttagttg
     6481 caactataat atctcctttt tttaccttag aaataaattt atcatcaata tcctccatac
     6541 aatgcgttgc tagttcttta taatcagcta tatttaaata tctagctggt attattacat
     6601 ctgtatctat attgtcaccg aatttaaaaa cacttccatt ggcaatcata aattttacct
     6661 cccttaaatt atttctgatg gttttgatat ttttccagtt atagctgatg ctgctgctac
     6721 agctgggctt gcaagataca cctctgaatc aacatgcccc attcttccta cgaaattcct
     6781 atttgttgtt gaaatggatt tttctcctgc tgcaagtata cccatatgtc cccctagaca
     6841 tggaccacaa gttggtgtag aaactgctgc tcctgcctct ataaaagtgg taatataccc
     6901 tttttctata gcttcaagat atactttttg agttccagga aatatcataa ctctaactcc
     6961 atctgctact tttttgcctt tcattatctc agctactact tcaaggtctg atattcttcc
     7021 atttgtacaa gagcctatta caacttggtc tatctttata tccttatcta tctcatctac
     7081 tgttctagta ttttcaggaa gatgaggaaa ggctactgtt tcttttagtt cagctaaatc
     7141 tatttcgtat acttcatcat agactgcatc ttcatctgct tcatatatat ttacatcttt
     7201 tgtcatagtt gaacacttat gtgaatttat atattccata gtcttatcgt ctactggaaa
     7261 aattccattt tttgctcctg cttctattgc catattacaa atagtaaatc tatcatccat
     7321 agataagtat tctactccat ctccacaaaa ttccattgac ttgtaaagtg ctccatcaac
     7381 acctatctcc cctattatat gaagtattat atctttacca cttatccatt tatttggttt
     7441 attcttcaaa acaaatttta ttgctccagg aaccttaaac caacattttc ctgtagccat
     7501 acctgctccc atatcagttg aacctacacc agtagaaaat gctcctaatg ctccatatgt
     7561 gcaagtatga gagtcagcac ctataattac atctccagca gttactatac ctttttcagg
     7621 aagaagaaca tgctctattc ccatatctcc tacatcaaaa aaatttacaa ctccttttga
     7681 ttttgcgaaa cttcttgtaa atttacattg ttctgcactc tttatatctt tattaggtgt
     7741 aaagtggtct aaaaccatca ctactttagt cttatcataa acatcttcaa ttcctaattt
     7801 ttcaaattct ctaatggcta ctggtgatgt tatatcatta cctaaaacta catctaaatc
     7861 tgcttcgatt aattgccctt tcttaacttc atttaattta gcatgtttgg ctaatatttt
     7921 ctgcgtcata gtcatcccca ttttttattt cctcctcaat ataactttta tttattgcat
     7981 tcataagtgc attaatagct gctgtattta tgttttccga tatacttaca ccaaaataga
     8041 cttcattatt gtgctctatt cctacataag ctacccctct tgaatgtgac ccttcctcta
     8101 atgcatgttc ccagtaatat ctaaatttat aatctttcat gccacattgc tttagtgcat
     8161 tattaaatga atctacaggt ccatttccta taccaacaat cctttgttca tttcccatat
     8221 aacttattct tgcagtcatc tcaatcatgt tagtatcatt agaatcatca ttttcatagt
     8281 ttaattcatc cattgatttt attttatact tcttaacttt ataagggctc tcaacttcaa
     8341 tatattcttt cttaaacaaa ttaaatattg cttcactact aagttcttcc ccaattctat
     8401 cagattccat tttgactaca tttccaaaat cagaatgcat attcttaggt atcataaatc
     8461 cataatctgt ttccattata taaacagctc ctccttttcc agattggcta tttatcctta
     8521 taatttcttt gtattctctt ccaatatcat gagggtctat tggtaaatat ggaacttccc
     8581 agtaatcatt atctctgttt ttcattgcta tcatgccttt tctaatagca tcttgatgtg
     8641 aacctgaaaa agcacaatgt acaagattac ctgcatatgg atgtctatca tgtaccataa
     8701 gttttgtaca atcttcatat atacctatta tcttatctat attgctaaaa tctagctctg
     8761 ggtctattcc ttgtgtataa agattaagtc ccacatttac tatatccata ttcccagttc
     8821 tttcaccatt tccaaatagt gttccttcaa gtctatcggc accagccaat aatccaagtt
     8881 cacttgcagc cgtacaagtt cctctatcat tgtgagtatg caaacttagt ataatagaat
     8941 ccctacaact tatattttta caaaaccatt ctatttggtc tgcatatacg tttggtgttg
     9001 ccatttcaac tgttgatgga agatttatta ttactttttt ttgagtagtt ggtttccaaa
     9061 catctatcac tgcctcacat atttcaagtg cataatccat ctctgttcct gtaaaactct
     9121 ctggtgaata ttcaaaagta aattctgttt ctggatattt ttttacttct tcattaaata
     9181 attttgctcc ttcaactgct atatctatta tttcttgttt actcatatta aaaaccacat
     9241 ctctttgaag aacagatgta gagttatata aatgtataat tgctttttta catcccctta
     9301 ttgattcaaa tgttttttct ataagatgag ccctagattg tgtaagtact tgtatagtta
     9361 catcatctgg aatcatattc tcatctatta attttcttaa aaatgtatac tctgtatttg
     9421 atgctgatgg aaatcctacc tctatttctt taaatcctgt atcaataagc attttgaaca
     9481 ttctgacttt ttcatttaca ctcataggtg ttggcagtga ctgatttccg tctcttaaat
     9541 cgacactaca ccaaattgga gccttaaata tttcattatc tggccattta cgatttacta
     9601 tttgcatttt atcatatttt ttatactttc cacacttcat gttatttccc cctttttctg
     9661 ttttttgtat tcagtatacc tcatatcgac gcaatcctgc acaattcata aggataaatg
     9721 tcaattttat cattagaata aaaaaaacct catctctaat aaaattagag acgaggtttt
     9781 gctcgcggta ccactctatt tagctttcta aaaagctccc ttagtaatag ccaatacaat
     9841 aattataatg actatatttc ctataacgtg gaattactcc gattattcta agatttaaat
     9901 cttagaaaac agctcctaga caagttcaga actatcaact actaaatcac accatccttt
     9961 agctctctga aagtttcatt gttcttacta cttctattca tcactttttt aatcatttaa
    10021 attttctaaa tattttgatt taatagttat tatatacaca ttaaaatgta ttgtcaacac
    10081 aaaaaataat tatctcaatt ttttattttt gataagcaat tctataaaac atgctaacta
    10141 ttgaaaacag tatgatatta tgccttaaac tttttcatct tttcatctat gatattcaat
    10201 aatttttttt catcttccaa actcaatgcc cttaatctaa ttttataatt agattcgtca
    10261 gtgtatatat ttaatatatt ttttactact tctatttttt ctattatctt ataattaaac
    10321 ttttgacttt gtttagattt tatactgaat atacattgat tatttattaa tattgaatga
    10381 ttatcgagag taatatatac ttttccctca tatttatttg aaaaatcacg accttgttta
    10441 aatagaaaaa ctgctgttat tatacataaa atatataata ttgtcgttga atatataaaa
    10501 attgtagcta aaattataag tgctaaaacc atatatatag tcattccttt tttaaaataa
    10561 ccattgtcat aataattcat atagataaac ttatttttac tcaaattttt tcacttccaa
    10621 gattctaaaa atttatatca aaaaattcta taatttcatc ttcatgataa tttatgacta
    10681 attcatctgg aaaatctact gcttctaaaa ctttttctgc attttcaaat tctcctatag
    10741 aataacatat atgagagtca gtaccaagaa ttactcttgc accatatgtt ttacacaatg
    10801 tcaacatatg acttacattt tcccaagtac ccgttctatg agagtttgaa cttaatgatg
    10861 aattatttat ttctaaaagg atatttttat ctttagcttt ttttactata ggttcataat
    10921 ctaaaggata cctactgtca tctggatgtc caattatttt taccttaggt ttatccataa
    10981 cttttaaaat agcatttgta ttttcttctt ttgtaccaga agctatacaa ggtctatgca
    11041 aacttgcgat tatataatcc aaatgttgca acatatcttc ttgaacatct aaattaccat
    11101 tataatccat tatatttcct tctattcctc taagaatctt tacgccttgc acttcacgtg
    11161 gaagcaaatg caaattataa aaatagaatg gatgtggtcc tcctggcata ttaggtccat
    11221 ggtctgatat tcctaagtat tttatattct tcttactcgc ctcttcgaca ttttccttga
    11281 aagtactatg tgcatgtcca cttattagag tgtgacaatg tacatccata atagactttt
    11341 tcattaaatt tcctcctaat attttacata aattcgtgaa aatagctaaa gggctatttc
    11401 aaaactaaag ctgtcataat agacagtgta acgttttaaa acagccccat tttcaattat
    11461 tttacacttc taaatcttta aatttatctt taaataattc tccaatactt cctaaagatt
    11521 cctctacttc taggtattct gttatatcct cttctggctc tctagttgct tcttttattg
    11581 aaaccaacat tctcttagtc tttggtttaa aatcaagaat cttaacttta acctcatctc
    11641 caatattaac aacattagta actttagcca ctctagtatc actcaattca gatattggta
    11701 aatacgcatc tacaccttct ttaatttgaa caaaagcccc tttttctatt attctaagaa
    11761 ctttaacatt gacaacatca tcaatttgta cttcttttgc tattaaatcc caagggtcat
    11821 tatttatgtc ttttaatgcc aaggcaattt ttttagtctc tttatttaca tccaacacat
    11881 aaacttctac ttcttgtccc tctgaaacaa catcttcaac actttcaact cttgtccaag
    11941 ctaaattatt tatatgtgct aatccttcaa tcccaccaat atccacaaat gcaccataag
    12001 gcattatctt tgtcacctta ccatctcttt tttgtccaac ttcaagagaa ttaaataagt
    12061 cttctttagc tgctttgata cgagcttttt cttcttctct ttcttgctta attcttgctc
    12121 tttcagcttc tttttctgcc ttaatttgag ctcttctttc ttctctctct ttatttatac
    12181 gctcttgtaa tacatctcta tgagatgcta caagtctatt ttttctaaca tccaattctt
    12241 ttatataaac ttctaagtta agaccaacaa atttagatgt atctgtaata aattttgtat
    12301 caagttgaga aattggtata aaaaatgtat atgtattgta attagcaaat acacctttat
    12361 ctatattctt ttcaacattt acagttatta ttctatgttc atcataagcc ttttgtaact
    12421 cggcaaaatc atttcttttg tcaagttgta atttagataa agttattgta ccatcttttt
    12481 gagatacttt tgttattaca gcagttattt catcacctat gtggtatata tcttctatat
    12541 attgattttt ttctatgttc aattcactta taggtattat tccatcaaac ccatagtcta
    12601 atcctaattg tacttcatca tttctcactg cagttatttt tccagttgtc aattctccaa
    12661 ctttcacttt gctgaatact tgttcttgct ggtcaagtaa ttcttgcatt gttaaatcat
    12721 tttccattat aaacatcctt tcctcttatt gattatcata tctgtaaata ttataccatt
    12781 aatattgcaa atacttacat ttttcttact ataattttta aaataaa
//
LOCUS       DAYAKB010000094        12803 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.094, whole genome shotgun sequence.
ACCESSION   DAYAKB010000094 DAYAKB010000000
VERSION     DAYAKB010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12803
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.094"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            122..469
                     /locus_tag="ACGI3L_003200"
     CDS             122..469
                     /locus_tag="ACGI3L_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9198896.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(619..1098)
                     /locus_tag="ACGI3L_003201"
     CDS             complement(619..1098)
                     /locus_tag="ACGI3L_003201"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9198897.1"
                     /translation="MAGAFAGGEGDFTTAFEPTATAMEKEGSGYIVTSIGKDSGEIPF
                     TAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKAMQPFFEDISLEDLTTV
                     VDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKDIVNTEFANNAIKNIK"
     gene            complement(1146..2651)
                     /locus_tag="ACGI3L_003202"
     CDS             complement(1146..2651)
                     /locus_tag="ACGI3L_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9198898.1"
                     /translation="MNVAIYLRKSRADEEAEHRGEFETLSRHKTTLLKLAREQNLNVI
                     EIKEELVSGESIEYRPKMLELLGEIKNNNYDAVLVMDIDRLGRGNMQDQGLILDTFKK
                     SKTKIITPRKTYDLNDEFDEEYSEFEAFMARKELKLISRRMQRGKIKSIEEGKFIAQA
                     PPYGYDIKYLNNKERVLVINEDKATVVKIIFDMYLKGDGACKISNYLNELGYKTTTGR
                     TWYEKGIRDIIKNKVYCGYIVWNKVERKRNSSRTRGIEEQIEVKGKHEPIISEDIWNK
                     AQNIRKKRINSPTPNNKITNPLAGIVKCGYCNHTLIAKSNTTSNGYEKYMVCTNCKNK
                     ATKLYILENKILEVLNKWLVNYRLSLKDEKDNSKPENTLEHTLINLNKELDTLEKQKE
                     RLHDFLEQGIYDSNTFGERLKILLSRIENAREAINKTNIDIEMQKERNTVKTQIVPQL
                     EKILSEYTEEKEPYLKNILLKSVINYAVYKKEPNQKSDDFSLILYPNIPRD"
     gene            complement(2850..3704)
                     /locus_tag="ACGI3L_003203"
     CDS             complement(2850..3704)
                     /locus_tag="ACGI3L_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9198899.1"
                     /translation="MEWIERLNKAINYIEENITKEIEYEQVAKIACCSTYHFQRMFAY
                     MADVPLSEYIRRRRMSLAAVELQNDDKKIIDVALKYGYSSPTAFNRAFKSIHGVAPSV
                     IKKREITTLKAFPPISFKISIKGAEEMNYRIEKKEAFRIVGVSQPLHNELEKNFEIVP
                     QMWQKVALDGTLQKLIPMMDSQLQGVLGISICNNSEEWKYFISVSSTKSIDNTLEEYT
                     VPAFTWAIFSGEGQCPQAIQELEKRIVTEWLPTSGYEYDNGPDIELYLNPDPQNAKFE
                     VWIPVVKK"
     gene            4089..4370
                     /locus_tag="ACGI3L_003204"
     CDS             4089..4370
                     /locus_tag="ACGI3L_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198900.1"
                     /translation="MPNIEKDLDGTTTITYLNDDIGVPTDENGYKISMTILHGKTICH
                     VVSPETILGRKFTLEEKQEKDTIIYGAIEKIMVDRQLQIKNSNKEVASH"
     gene            4520..5368
                     /locus_tag="ACGI3L_003205"
     CDS             4520..5368
                     /locus_tag="ACGI3L_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HFG9198901.1"
                     /translation="MIKSFLMLGQSNMAGRGFISEVTPIYNERIQMLRNGRWQMMTEP
                     INYDRPVSGVSLAASFADAWCCENQEDRIGLIPCAEGGSSLDEWNIDGILFKHAISEA
                     KFAIQSSELTGILWHQGENDSNNGNYKFYYKKLLSIIETLRKELNIPDIPIIIGGLGD
                     FLGKVGFGKSCTEYVFINQELQKFAFEQDNCYFVTATGLTSNPDGIHIDAISQRKFGL
                     RYFEAFHKKKHIMEALANESELIIPSNSKTYTKTEKIYINSMDLALGKISYDEFESKL
                     IKLNDN"
     gene            5420..5941
                     /locus_tag="ACGI3L_003206"
     CDS             5420..5941
                     /locus_tag="ACGI3L_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9198902.1"
                     /translation="MIPLLILGLLKQNPNSYGYELLALMEKKHYKYIVNFTKGSFYYN
                     LQQLEEKKFIEKVENKQSNKNRETHNYIITELGCQEFEKLMYKYGSKTEYINLSFYAT
                     LLFANDYKNEKLIELLETQIKQTQVRISLLNESIENDKTNSHYFNRMLENSRSHHLVN
                     IEWFEKLLNDIRD"
     gene            6310..6825
                     /locus_tag="ACGI3L_003207"
     CDS             6310..6825
                     /locus_tag="ACGI3L_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFG9198903.1"
                     /translation="MNDARIISQIKAGKKELFDTLIKKYYDSIYCYCYRHVDNKMTAQ
                     DLTQDVFVTVINNIENYKHYGKFENYLYVIAKNKCKDFWKKKQPIYLESLDKEISNQE
                     LSDIENKMFIKEALTKLPELEFEVIILRYYHDLRFKDIAKIMESSVSVTKYRMSRALK
                     KLELYLEGGKL"
     gene            6822..7583
                     /locus_tag="ACGI3L_003208"
     CDS             6822..7583
                     /locus_tag="ACGI3L_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198904.1"
                     /translation="MNNKEIKRSLQKYKVPKYDSSALEKTIKTIHELTLSNTYKRMNN
                     KDFFISQIGFIRKRTWIMQFLILCTICIFLFSTSADSNSFYNSLSLISIASPLFVLTN
                     IEELTKVYNSSILEIEFSTKNTLHKIIATRMLIFGISDLLFMIIILVSAKQIIDVNIL
                     YIIIYILVPFNLMCIGCMEIINRNKGKHTNYYCMIYGISLVLLIVTLSNFRDNLYQFE
                     AINQWLIVFLVTAVTLIYEIRKTWRHLCSFENIII"
     gene            7621..8487
                     /locus_tag="ACGI3L_003209"
     CDS             7621..8487
                     /locus_tag="ACGI3L_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198905.1"
                     /translation="MELSVERLTKQYNNKIIVDKIDFKLNEGIYGFLGENGAGKTTLM
                     RMICGILSPTSGEVKVDGKNNLDMGEDFRDMIGYLPQNFGYYPDFTAKEFMLYIASLK
                     GLMPSYAKRKTQELLEMVGLSEVINKKIRTFSGGMKQRLGFAQTLLNDPKILILDEPT
                     AGLDPKERVRFRNLISEFSKEKIVILSTHIVSDVEYIADKILIMKKGRFVLTGSIEEV
                     TSKIKDKVWKCVVNENEIDYMSDRYCLANIHHSGGVANLRIVSDIKPHDNACNLKPTL
                     EDLYLYCFNEVL"
     gene            8508..9749
                     /locus_tag="ACGI3L_003210"
     CDS             8508..9749
                     /locus_tag="ACGI3L_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFG9198906.1"
                     /translation="MSTLIKFELKKIIKRKSTIAVILGSLFLSIILFALMPIQEKAND
                     ESGKEYRGLQAIELKKQQSKLNEGYITDKKVKNSIRDYQKMFNNPNNITTDEGGFSNF
                     KPDIYWKFFYPNKAFYNFIIESYSNPNDYNPEIIKSMPLEDGVNFYKFRNEKVNTILN
                     MEYPDKNYTQKEKDFWLSKNKDIEEPYLNGYYQGWNYFLLARDLLIFTIVAVCISTAS
                     VFSGEYQSGADSIILSSKYGKTKVITAKIVSSFLFGTIIFTINTIVSIGILLLSFGID
                     GWNLPLQLTTSSIPYPYTFLQAILLSVLIIYMILILLISFTLLLSSYMKSPFPVLITN
                     IILLFVPIFLKYSETNKLYNQILNVLPSNAISFSFTNYVDYKFGNLIIALPTMIIFTC
                     LVLTVVFLPFIKNNFKKHQVN"
     gene            complement(9973..10545)
                     /locus_tag="ACGI3L_003211"
     CDS             complement(9973..10545)
                     /locus_tag="ACGI3L_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9198907.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQKSV"
     gene            10931..11665
                     /locus_tag="ACGI3L_003212"
     CDS             10931..11665
                     /locus_tag="ACGI3L_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9198908.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDGYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(11808..12299)
                     /locus_tag="ACGI3L_003213"
     CDS             complement(11808..12299)
                     /locus_tag="ACGI3L_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFG9198909.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            12648..>12803
                     /locus_tag="ACGI3L_003214"
     CDS             12648..>12803
                     /locus_tag="ACGI3L_003214"
                     /inference="COORDINATES: protein motif:HMM:NF037917.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198910.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDI"
BASE COUNT         4759 a         1600 c         1760 g         4684 t
ORIGIN      
        1 tagtattata cttatattta aaaataaaag aattttattc ctattgtgta aagtgagaat
       61 actattttct tatattggta taataatagt aaatctaata tagaaaagag gtatttctag
      121 tatgcatgaa aataaaaaaa atctattaga cggaagctta gctcaatata atgatacagc
      181 agttccaaaa ataccagtat ttgctggtaa cgatataact tcagaagttt attattttaa
      241 acctaatcaa gttcttaatg ctcatagaca ccctaatggt gaacaaatat ttgtgttcct
      301 aaaaggagaa ggtaaaatga aacttggtga gcatgaatgt gatgtaaaaa acggcgatac
      361 tgtatttgta ccaacaggag agtggcatga aattactaat ggaagcaatg aagaaatggt
      421 agccgttcaa attacaaaaa ttaatgctgg agcagaatac agaggataga tatataagta
      481 cagttagtac tttaatatct attttattat ataaacttta atctcaaata taaaaagagt
      541 cttttaaaag gctcttttta tatttttgtt aattttcatt ataaaaacaa gaaaatatct
      601 agctaaaact aatatatttt atttaatatt ttttatagca ttgtttgcaa actcagtatt
      661 tacgatatct ttataaggtg cttccttatc tagttcttta gcttctttca taacagtcat
      721 caatttcttc aaaccttcct cttttaatac aggattttga gaccatgcat ctattgattt
      781 atatctatct acaactgttg ttaaatcttc taaagatata tcttcaaaga aaggttgcat
      841 agccttagct acttctttgc tagatgcttg ttgaatccat aattgacctt tataaacagc
      901 atttgtaaat ctttgaatta aatctttatt gtttttcatg tatgatctcg tagtagagta
      961 tgctgtaaaa ggtatttctc cagaatcttt tcctatagat gtaactatat atccactacc
     1021 ttctttttcc attgctgttg ctgtaggttc aaatgctgtt gtaaagtcac cctctccacc
     1081 tgcaaaagct ccagccatta caccaaattg gtaatcagtc tatttataac atttaaaaca
     1141 tataattaat ctcttgggat attagggtaa agtattaaag aaaaatcatc agatttttga
     1201 ttaggttctt ttttatagac tgcgtaattt attacacttt taagcaatat attttttaga
     1261 taaggttctt tttcctctgt atattcactt aaaatttttt caagttgagg aacaatttgt
     1321 gttttaactg tatttctttc cttttgcatt tcaatatcta tatttgtttt attaatagct
     1381 tctcttgcat tttctatacg agataagagt atttttaaac gttccccaaa tgtattactg
     1441 tcataaattc cttgttctaa aaaatcatgt agtcgttctt tttgtttttc taaagtatcc
     1501 aattctttat ttaaatttat caaggtatgt tctaaagtat tttcaggttt agagttgtct
     1561 ttttcatctt ttaaagatag tctataattt actaaccatt tatttaagac ctctaatatt
     1621 ttattttcta atatgtatag tttagtagct ttatttttac aattagtaca aaccatatat
     1681 ttctcatatc catttgatgt agtattagat ttggctatta aagtatgatt acagtatcca
     1741 cattttacaa ttccagccaa tggatttgtt attttattgt ttggagtagg ggaattaata
     1801 cgtttttttc ttatattttg tgccttattc catatgtctt cacttattat tggttcatgc
     1861 tttcctttta cctcaatttg ttcctcaatt cctcttgttc tactagaatt tcttttcctc
     1921 tcgactttat tccatactat atatccacaa tacactttgt tttttataat atctcttata
     1981 cccttttcat accaagttct acctgttgtg gtcttataac caagttcgtt taaataattg
     2041 gatattttac atgcaccatc tccttttaaa tacatatcaa agattatttt aacaacagtt
     2101 gctttatctt catttattac aagtactctt tctttattat ttaaatattt aatatcatac
     2161 ccataaggag gagcttgagc tataaattta ccctcttcaa tacttttgat ttttcctctt
     2221 tgcatacgtc tagatattaa ttttaattcc ttacgagcca taaaagcttc aaattcagaa
     2281 tactcctcat caaactcatc atttaaatca tacgtttttc taggagtaat aattttcgtt
     2341 ttagattttt taaatgtatc tagtattaac ccttggtctt gcatattacc acgacccaaa
     2401 cggtcaatat ccatcactaa aacagcatca tagttattat ttttaatttc acctagtaat
     2461 tctagcatct taggtctata ttctatactt tccccagaaa caagttcttc tttaatttca
     2521 atgacattta aattttgttc tcttgctagt tttaaaagag ttgtcttatg tctacttaga
     2581 gtttcaaatt cacctctatg ttctgcttct tcatcagctc tgcttttgcg taaataaatt
     2641 gccacattca ttaaatcaca ccccttgaat atattatatt cagtaacaga ttgattatat
     2701 ttaaaacaca aaaataaacc ttcaaaatac aagatatatt ttttaggttt atttttatac
     2761 agtaaatttt atagtatatt taaaagcttg taatctaagt aaatatttat actattaatt
     2821 ttatgctttc ttcatttttt aattttaaac tattttttta ctacaggtat ccatacttca
     2881 aatttagcat tttgagggtc tggatttaag tacagttcaa tatcaggacc attatcatat
     2941 tcataaccag aagtaggtaa ccattctgtt acaatacgct tttctagttc ttgtattgct
     3001 tgtggacatt gtccttctcc agaaaatatt gcccaagtaa aagctggaac agtgtattct
     3061 tctaatgtat tatctataga ttttgtactt gaaacagata taaaatactt ccattcttct
     3121 gaattattac aaatacttat acctaataca ccttgaagtt gactatccat catagggatt
     3181 aatttttgaa gcgttccatc taaagcaacc ttttgccaca tttggggaac aatttcaaaa
     3241 ttcttttcta gttcattatg aagtggctga gatacaccaa ctatacgaaa tgcttctttc
     3301 ttttcaattc tataattcat ttcttcggct cctttaatac taattttaaa actgattgga
     3361 ggaaaggctt ttaaagttgt tatttctctt ttttttataa ctgatggggc aacaccatga
     3421 atacttttaa atgcacgatt gaatgctgtt ggagaagagt atccatattt taaagccaca
     3481 tcaattatct ttttatcatc attttgtaat tctacagctg ctaaagacat ccgtctacga
     3541 cgaatatatt cagaaagtgg tacatctgcc atataagcaa acattctttg aaaatgatat
     3601 gtagaacaac aagctatttt tgccacttgt tcatactcaa tttcttttgt tatgttttct
     3661 tcaatatagt taattgcttt gtttaatctt tcaatccatt ccataaaatc agctccttgt
     3721 aatttatata atatctattt taaaatagtt aatcctctct ttctatgcac taattaacta
     3781 gcttaataaa gaatgaacat gagaaagtct gtaattaact acaaaaatga acaaatagta
     3841 ttgtttttca cattaaagta tatcacaaat tagtatctaa tttttatata agataacagt
     3901 tttaatttat tatgaaattt ttataatatt ttagcttaga catttaatta tatataacat
     3961 tttatttata gttaactatt tttgaagttt acccttaatc aagcaacact tagttattca
     4021 attataaata atgattgaga ataggacaat ttttaagata cataaaatat aaagaggagg
     4081 ggatttaaat gccaaacata gaaaaagact tagatggtac aactactata acatacctca
     4141 acgacgatat aggtgttcca acagacgaga atggatataa aatatctatg acaatactac
     4201 atggaaagac aatctgccat gtagtatctc ctgaaacaat cttaggaaga aagttcacat
     4261 tagaagaaaa acaagaaaaa gatacaataa tatatggagc aatagaaaaa ataatggtag
     4321 acagacaatt acaaataaaa aattcaaaca aagaagttgc tagtcattag cacttcttta
     4381 ataagtaaag taggacaagt attttttata atattattga cttatagtct aattagacta
     4441 taatataaac atagatagtc taattagact actattaaaa ataaatacaa taagaattta
     4501 agaaaggata ataataataa tgattaaatc atttttaatg ttaggacagt ccaatatggc
     4561 tggaagagga ttcataagtg aagtgactcc aatttataat gaaagaatac agatgttacg
     4621 taatggaaga tggcaaatga tgacagaacc tattaattat gacagaccag tttctggggt
     4681 aagtcttgct gcatcatttg cagatgcatg gtgctgtgaa aatcaagagg atagaattgg
     4741 gctaattcct tgtgctgagg gaggcagttc cttagatgaa tggaatatag atggtatact
     4801 ttttaaacat gctataagtg aagctaaatt tgccatacaa agcagtgaat tgacaggaat
     4861 tttatggcat cagggagaaa atgacagtaa taatggcaac tataaatttt attataaaaa
     4921 attactttct attattgaaa ctcttagaaa agaattaaat attccagata taccaattat
     4981 tattggtgga ttgggagact tcttaggaaa agtaggtttt ggaaaaagtt gtactgagta
     5041 tgtatttatc aatcaagagt tacagaaatt tgcttttgaa caagataatt gttactttgt
     5101 tacagcaaca ggtcttacat ctaatcctga tggtattcat attgatgcaa tatctcaaag
     5161 aaaatttgga ttacgttatt ttgaagcttt tcataagaaa aagcatatta tggaagcatt
     5221 agctaatgaa agtgagttga taataccgag taattccaag acatatacaa aaacagaaaa
     5281 aatatatata aatagtatgg acttggcact aggaaagata tcatatgatg agtttgaatc
     5341 taaacttatt aaacttaatg ataattagat aaaatattca ttaatatact aataaatata
     5401 gattgaaaga ggtgattttt tgataccatt attaatttta ggattattaa aacaaaatcc
     5461 aaattcttat ggatatgagt tattagcatt aatggaaaag aagcattaca agtacatagt
     5521 aaatttcact aaaggttctt tttattataa tttacagcaa cttgaagaaa aaaagtttat
     5581 tgaaaaagtt gaaaataaac aatctaataa aaatagagaa actcataact acataattac
     5641 tgaacttgga tgccaggaat ttgaaaaatt aatgtataag tatggttcta aaacagagta
     5701 tataaatcta tcattttacg caacactatt atttgcaaat gattataaaa atgaaaagtt
     5761 aatagaatta ttggaaacgc aaattaagca aactcaagta agaatttctc tattaaatga
     5821 atccatagaa aatgacaaaa caaattcaca ttattttaat agaatgctag aaaattctcg
     5881 ttctcaccat ttagttaata ttgaatggtt tgagaagttg ctaaatgata ttagagattg
     5941 attttaataa taaaaaaaca tacatatata ttttatataa atgtatgata tatagattaa
     6001 aaataaggca gataattttc aattgaatat ctgtcttttt gttatataag atgttaaaag
     6061 aaacttatac tatgtaagta aaatttataa atataaagtt gttcattgtt gaattacaga
     6121 cacttaagat gaaaagtatg acatttgata taataaaatt gtttaagtat taattatgag
     6181 tattaattaa tggtatagat aattttaata taactgtatt tataaataat tataaaataa
     6241 taaattaatt tttttatact gactttttta tagtataaat cgttatatat aatgacggag
     6301 gtgataatag tgaatgatgc tcggattata tcacaaataa aagcaggaaa aaaagaattg
     6361 tttgatactc taataaaaaa atactatgat agcatctact gttattgtta tcgccatgta
     6421 gacaataaaa tgactgcaca agatttaact caagatgtat ttgtaacagt tataaataat
     6481 atagaaaatt ataaacatta tggtaagttt gaaaactatt tgtatgttat tgcaaaaaac
     6541 aagtgtaagg atttttggaa gaaaaaacaa ccaatatatt tagagtcatt agataaggag
     6601 atatcaaatc aagaattatc tgatatagaa aataaaatgt ttataaaaga agctttgact
     6661 aaattaccag aattagaatt tgaagtgata attttacggt attaccatga tttaagattt
     6721 aaggatattg ctaaaattat ggagtcaagc gtctctgtca caaagtacag gatgagtagg
     6781 gcattaaaaa aactagaatt atatctggaa ggaggtaaat tatgaataat aaagaaataa
     6841 aaagaagtct acagaagtat aaggttccca aatatgattc ttcagctctt gaaaagacta
     6901 ttaaaactat acatgagtta acgcttagta atacttataa aagaatgaat aataaagact
     6961 tttttatatc tcaaattggt tttataagaa aaagaacttg gattatgcaa tttctaatac
     7021 tatgtacaat atgtatattt ttatttagta catcagcaga tagtaattca ttttataata
     7081 gtttatcctt gatttctata gcatcaccac tttttgtact gacaaatata gaagaattaa
     7141 caaaagtgta taatagtagt attttagaga tagaattttc aacaaaaaat acattacata
     7201 aaattattgc tactagaatg cttatatttg gaataagtga tttattgttt atgattatta
     7261 ttttggtatc tgcaaaacaa atcattgatg taaacattct gtatataata atttatatac
     7321 tagttccttt taacctaatg tgtataggat gtatggaaat tataaataga aataaaggta
     7381 agcatacaaa ttattattgt atgatatacg gtatatctct tgtattatta atagttacac
     7441 tgagtaactt tagagataat ctatatcaat ttgaagcaat aaatcaatgg ctaattgttt
     7501 ttctagtcac agcagtaaca ttaatatatg aaataagaaa aacgtggaga catctttgtt
     7561 catttgaaaa tattattatc taagtaaaaa ataagaatac acagtatcag gaggaatagt
     7621 atggagttaa gtgtagaacg tttaacaaaa cagtataaca ataaaattat agtagataaa
     7681 attgacttta aattaaatga gggtatatat ggatttttag gagaaaatgg agctggaaaa
     7741 acaactctta tgagaatgat ttgcggaata ttaagtccta catctggaga agtaaaggtg
     7801 gatggtaaaa ataatttgga tatgggagaa gattttagag atatgattgg ataccttcct
     7861 caaaactttg gatactaccc agattttact gccaaagaat ttatgctata tatagcatca
     7921 ttaaaaggat taatgcctag ctatgcaaag agaaaaacac aagaattatt agaaatggta
     7981 ggattatcag aggtaattaa taaaaaaata agaacatttt ctggaggtat gaagcaaagg
     8041 ctaggatttg ctcaaacact acttaatgac cccaaaattt taatattaga tgagccaaca
     8101 gcagggctag accctaaaga acgagttaga tttcgcaacc taatttcaga attttctaag
     8161 gaaaagattg ttatattgtc tactcatatt gtgtctgatg tagaatatat tgcagataaa
     8221 attttaataa tgaaaaaagg aagatttgtt ttaactggct caatagaaga agtaacttca
     8281 aagataaaag ataaggtatg gaaatgtgtg gtcaatgaga atgaaataga ttatatgtct
     8341 gatagatatt gtttagcaaa tatccatcat tctggtggag ttgcaaatct tagaattgta
     8401 agtgatataa agccacatga caatgcatgc aatttaaaac caacattaga agatttatat
     8461 ttatattgtt tcaacgaagt actataaata tacataagga gataggtatg tctacattaa
     8521 ttaaatttga gttaaaaaaa ataataaaaa gaaagtctac aatagcagtt attttaggaa
     8581 gtttattctt aagcatcatt ctttttgcat taatgccaat tcaggaaaaa gctaatgatg
     8641 aaagtggaaa agagtatagg ggtttacagg ctattgagct aaaaaagcaa caatctaaat
     8701 taaatgaggg atacataaca gataaaaaag taaaaaactc aatcagagat taccaaaaaa
     8761 tgtttaataa tccaaataat attacaacag atgaaggtgg gttttcaaat tttaaaccag
     8821 atatttattg gaaattcttc tatccaaata aagcttttta taattttata atagagtcat
     8881 atagtaatcc aaatgattat aatccagaaa taattaaatc aatgccttta gaagatggag
     8941 ttaattttta taaatttaga aatgaaaaag taaatacaat attaaatatg gaatatcctg
     9001 ataaaaatta cacacagaaa gagaaagatt tttggttgtc taaaaataag gatatagaag
     9061 agccttattt aaatggatat tatcaaggat ggaattattt tctattggct agagatttac
     9121 taatttttac tatagtagct gtctgcataa gtacagcttc tgtattttca ggagaatacc
     9181 aatccggtgc tgattcaata atattatctt ctaaatatgg aaaaacaaaa gttataacag
     9241 ctaaaatagt aagttccttt ttatttggta cgattatttt tacaataaat acaattgtgt
     9301 ctattggtat acttctttta tcttttggaa ttgatggatg gaatttacca ttacaactta
     9361 caaccagttc aattccatac ccatatacat ttttacaggc aatattacta agtgtgttaa
     9421 ttatttatat gatattaata ctattaatta gttttacact tttattatca tcttatatga
     9481 aatcaccttt tccagtttta attacaaata taatattact atttgtacca atatttttaa
     9541 aatatagtga aacaaataag ttgtataatc aaattctcaa tgttttacca tcaaatgcta
     9601 tttcattttc atttactaat tatgtagatt ataaatttgg taatttaata atagctttac
     9661 ctacaatgat tatttttaca tgcttagttc ttacagttgt ttttttacct tttattaaaa
     9721 ataattttaa aaaacatcaa gttaactaaa atatatatta taaaaagaag gtgtcttaaa
     9781 atgaactttt tagcttatta ggcactcttc tttgtattaa tttaaatata ttttagtatt
     9841 agattaaata tgttttcatc attttaacaa tgaaaaagag ctttatctct attttgagat
     9901 agctcttata aagttaaata ttaaattgat aactataaaa tatgtagttt gaatttataa
     9961 tttgtgttat aatcatactg atttttgtac atcagttctt acattaacat tgcctgcttt
    10021 tagattttct ccaatagtaa gacctttttc ttttagaaca tattcaaaag tcattagtgg
    10081 aactccacct tttctaccac ctaatatttc ggttcctttt aaatcattgt aagagaaatt
    10141 aggcattttt ttcctagcaa ctagaaaact accatctctt tttgtcaatt gagcaaagtt
    10201 cactgcataa tcgtttttgt tttgattata tacatatata gatgcttcag gacccattaa
    10261 acctacgttt gcttcacctg aaatcaaagc tgccatagtt ttatctgcac cttgggtatt
    10321 tataaggtca atctttatac cttcatcttc aaagaatcct ttcgtaatag cagcatactg
    10381 tggagcataa aaaacagagt gagtaacttc tgctatagtt actttatcca gatttttaga
    10441 cgaagaagat tcaccttttt tgtcattaga gttaaaatca catccagtta gacatattgt
    10501 acttacaatg atagagcttg ctattgcgac tattttttta aacataataa atacctccca
    10561 taagacatac gaatagtata tagtattaaa aatttattgt agttgttaca aaaatgtatc
    10621 tatgcttata atatttctac aaaaacttaa taataatttt cagctttatg tttagttttt
    10681 tcagtaatgt gtaatattgg ataaattata ttgattattt ataaactaag taataaaatt
    10741 aaaataatat cacttttttg tctattatat ataaggaaaa attttttaat aatataaatc
    10801 atattcattt atattattaa aaaatttgtt tatagaaact tttattattt tatataaaag
    10861 tgataaaaac ttatattttg tatttaatag agtgttgcta agtgaatata tttaaaatgg
    10921 aggaaacttt atgaaacaaa ataaatatga tgatgataga ttttttaata aatacagtaa
    10981 aatggaacgt tctacaaatg gattagcagg tgctggagag tggcatgttt taaaaaaaat
    11041 gttacctgat ttcaaaggaa aaagagtttt agatttagga tgtggatttg gatggcattg
    11101 tcaatatgca gttgagaatg gagcaatttc tgctgttgga gttgatattt cagaaaaaat
    11161 gttaaaagaa gctagaaaca aaacgcaact tgataatata aattacatat gtatgcctat
    11221 tgaagatatt aattttccaa aagatagttt tgatgtagtt attagttcct tggcatttca
    11281 ttatattcaa tcatttgaag atatatgtaa gaatataagt aattgtcttt caaataaagg
    11341 taattttgta ttttctgttg aacatcctat atttactgca tatggaagtc aagagtggta
    11401 ctgtgataaa gatggcacta atctacactg gccagtagat ggatattttg aagaaggagt
    11461 acgtaagtca aattttctag gagaagaggt tataaaatat cataaaacat taacaactta
    11521 tttaaatacg ttaatgaaaa caggatttga aatattagaa attattgaac ctcaaccaga
    11581 agaaaaactg ttagatacaa ttcctgatat gaaagatgag ctacgtagac ctatgatgtt
    11641 acttgtatct gcaaaaaaaa gataagtaaa tataaataat cattattgta gaaaaaaagt
    11701 tgtagaaaat aattacacta atggagatga ttataccagt ggtattaatt acaccagtag
    11761 taaggaggca aaagcattcg ttgcttttgc cattttttaa gttgcaatta tacttctacg
    11821 tagtatattt cgtttccatt ttcttctata agctttttca tatcttcaaa ttttaaaaat
    11881 acagtagcag tattatcatt tggatgtata cctattttat ccatttttaa taaatcttta
    11941 tcaaatacaa cttttacaac agcctcttta tcatttaata taccaaaagg agtcacagct
    12001 ccttttgtaa gtttcaagta tttttgaagt ctttcttccg atgcaaaact aagaggttta
    12061 ctatcaattt gttgacgaat atcttttaaa tctgcttttt tgtctttacc taatacaact
    12121 aaaaaatgtt cttttccttt agcatcacga agaaataggt tttttacaac aaattccata
    12181 tgtaatgttt ttaattcttc catttcttca attgtataaa ctggtggatg atttacagcc
    12241 tcataaggta tgcttaactc atctaatttt ttatatactt cctgttgttg attgttcatg
    12301 atttcctccc attagaaatt tattttatat ataaataata ttatcacaga aaactttaaa
    12361 agaaaacgtt ttatataata tagacaatag attatatttt tataaagaag caagaatact
    12421 caataaaact taaagaaatt aaacaatttc taaaaatacc ttgaaaatag aaccttattt
    12481 gccatttata aattatataa aaagggatta tataaagtca tatatgaaaa aactatatta
    12541 tactatcttt tctttttgga ataaactata ctttaaatat agatatttaa tttaaataaa
    12601 ttttacagta ttaatagtaa attatcttag aaaggaatgt gctttatatg tctacagaca
    12661 aagttgttgg aatcatagat gaagaaacgg cagaacttgc aggaattgaa tatactggta
    12721 aaatttatgc ttcttctggt gttataaaac atataaagaa aaaacataga tgtcaactga
    12781 gtaaggatat ttttaatgat ata
//
LOCUS       DAYAKB010000095        12509 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.095, whole genome shotgun sequence.
ACCESSION   DAYAKB010000095 DAYAKB010000000
VERSION     DAYAKB010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.095"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..772
                     /gene="thiM"
                     /locus_tag="ACGI3L_003215"
     CDS             <1..772
                     /gene="thiM"
                     /locus_tag="ACGI3L_003215"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HFG9198911.1"
                     /translation="DVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSYEEVEEM
                     VSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAELTSRLLN
                     EVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVVATGKID
                     IITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLTMSLSGE
                     LANLNNPPIGTFKENLMNAIYQMDIDALSKNSNIEFLN"
     gene            795..1427
                     /gene="thiE"
                     /locus_tag="ACGI3L_003216"
     CDS             795..1427
                     /gene="thiE"
                     /locus_tag="ACGI3L_003216"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFG9198912.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            1566..1868
                     /locus_tag="ACGI3L_003217"
     CDS             1566..1868
                     /locus_tag="ACGI3L_003217"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9198913.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(1934..2683)
                     /locus_tag="ACGI3L_003218"
     CDS             complement(1934..2683)
                     /locus_tag="ACGI3L_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198914.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDIMPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(2677..3639)
                     /locus_tag="ACGI3L_003219"
     CDS             complement(2677..3639)
                     /locus_tag="ACGI3L_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9198915.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(3643..4101)
                     /locus_tag="ACGI3L_003220"
     CDS             complement(3643..4101)
                     /locus_tag="ACGI3L_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9198916.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            4457..4813
                     /locus_tag="ACGI3L_003221"
     CDS             4457..4813
                     /locus_tag="ACGI3L_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9198917.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            4885..5601
                     /locus_tag="ACGI3L_003222"
     CDS             4885..5601
                     /locus_tag="ACGI3L_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198918.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            5594..6418
                     /locus_tag="ACGI3L_003223"
     CDS             5594..6418
                     /locus_tag="ACGI3L_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198919.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            6430..7629
                     /locus_tag="ACGI3L_003224"
     CDS             6430..7629
                     /locus_tag="ACGI3L_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198920.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            7638..8450
                     /locus_tag="ACGI3L_003225"
     CDS             7638..8450
                     /locus_tag="ACGI3L_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198921.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            8461..9729
                     /locus_tag="ACGI3L_003226"
     CDS             8461..9729
                     /locus_tag="ACGI3L_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198922.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIIDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            10095..11276
                     /locus_tag="ACGI3L_003227"
     CDS             10095..11276
                     /locus_tag="ACGI3L_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9198923.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(11418..12335)
                     /locus_tag="ACGI3L_003228"
     CDS             complement(11418..12335)
                     /locus_tag="ACGI3L_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotA family spore coat protein"
                     /protein_id="HFG9198924.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
BASE COUNT         4937 a         1348 c         1967 g         4257 t
ORIGIN      
        1 agatgtaaaa aaattaaatc cattggtaat tcattatact aataatgtaa ctataaatga
       61 ttgtgctaat gtaactttag ctgtaggagc aagtcctctt atgagttttt catatgagga
      121 agtagaagaa atggtaagtg tagcaaactc tgtagtaata aatataggaa ctatgaactc
      181 aaatatgttg gatttattcc tattagctgg aaaagcagca aataagtaca ataaacctgt
      241 tgttttggac ccagttggag tatttgcaag caaagcgaga gcagaactta caagtagact
      301 tttaaatgaa gtcaaattta gtgttgttaa agggaatgta tcagaaataa agtttatagg
      361 tggctttaat gtaaggggta aaggtgtaga ttcatttgat gaagaagaag attctactga
      421 gataataaga aagattgctg aaaagcttga atgtgtagtt gtagcaactg gaaaaataga
      481 tataataact aatggtaaag gtacatataa aataaacaat ggaactgata aattaaaagg
      541 aattacagga actggatgta tgactgctag cttgattgca agttttatgg ctgttactga
      601 gaatatatta gaagcagcaa caatgggtgt tcttacaatg tctttaagtg gggaattagc
      661 taatttaaat aatccaccaa taggtacatt taaagaaaat cttatgaatg ctatttatca
      721 aatggatata gatgctttaa gtaaaaattc taatattgaa tttttaaatt aataaagagt
      781 aagggagact taaaatgatt gataaagaat ctttaaaaaa atgtttaaag ttgtatttag
      841 taactgactc tgaaatgctt aaaggtagag acttttataa atgtcttgaa gatgcaatat
      901 cttctggaat aacaactgta caacttagag aaaaaaatgc ttctggaaga gagtttttaa
      961 gaaaagctat gaaacttaga gaaataacta aaagatatgg tgttaagttt ataataaatg
     1021 atagagtgga tatagcactt atttgtgatg cagatggagt acatgtagga cagagtgaca
     1081 ttgatgttag agaggttaga aagcttatag gaaacaataa aattctagga gtatcagcaa
     1141 gaactttaga agaagctatt tgtgcaaaaa atgatggcgc agactattta ggtgtagggt
     1201 ctatattcac aacatctact aaattagatg caaaatcagc ttcgtttgaa actgttaaag
     1261 aaattaaaga aaaagtagac atgccatttg tactaattgg aggtataaat ttagacaata
     1321 tagataaact taaatgttta gaaagtgacg ggtatgctat aatatcagct atattaaaag
     1381 ctgaagatat ctctaaagaa gtggaaaagt ggacattaaa aatataaaat tggctctggt
     1441 agtgaaaaaa atggaaaaat ttgatataat ctaagagtaa aatttaagca attataaatg
     1501 ataaactttt ctacatatac tttttaatca agatatatgt agatttggtt aaaaaggagc
     1561 tataaatgat taggatattg ttagtgtgtg ttggaggcat gtcttctacc ctattggtaa
     1621 ataaaatgga gaaggatgca aaaaaaagaa atatagactg taaaatatgg gcagttggag
     1681 aaggagatat aaaatcggag cttgataact ttgatatttt acttcttgga ccacaactta
     1741 gatttatgct tgatgacgta aagtctatag ttggagatag agctccagta tctataatag
     1801 atatggtaaa ctatggcact tgtaatggtc atgctgtgtt aaattcggtt ttagaaatat
     1861 taaaataaat aataaaagtg gattctatat aatagagtcc atttttatta tttgttatta
     1921 ataggcttaa aacttagctt accatttctt tttttaatct ccacatagca agtgaaaaac
     1981 ttgaacagca caatattaaa aatagtagga taacaggcat tatatctcca ataagaatag
     2041 tctcaccaaa tattaagcta cgtaaagcgt taataacatg ggtaaatgga ttgagcatca
     2101 ctgctacttt taatcctcca gataaacttt ctatagggaa aagagctgaa cttaaaaaga
     2161 aaataggaag tacaattgca gtcataattg tttcataaac tatttcattt ggcaataata
     2221 aacttataga ataagctaga cttgataaaa agaaggctgt cataaatatc agtactatca
     2281 taagtaggat tccaccaatg ccagattcta tccttactga gaagaatata cttactatac
     2341 acaaaatagt tacttctatg aaagaaacta agatagcttc taataattga ccaaggacga
     2401 ttgaatacct gctgataggt gcaattaaga ctctatagaa acttccactg ttcttcatta
     2461 taaagtttat aataccacca ctactacaag aagaaaacac aaccagtaca atgatacctg
     2521 gtagtataaa agcagtataa ttattgatat ttatattatt catagtttgg tttgcaatag
     2581 aactataaag cacaagccaa agaaaaggtt gtaatatagt aactacaaat gagattggat
     2641 ttttaaaacg ccacttcata ctacgccata agatatttaa cattcccatt cctcctttaa
     2701 gcttttttta gaacttgtaa gtgctaaaaa tacatcttcg agacttggct ctacaatttc
     2761 tattgcatca aattctatat catgttctaa aagccattta tttattaaag taaaagcagt
     2821 tctactatcg tttacactta taaaaattga attttctcgt acgctcataa actttactaa
     2881 accagtactt ttaattgaat ctttatattt ttttatatct tcagtattat gaaaagttat
     2941 acgtagtata ttttgtctaa tgtaactacg taaacttgat ggtgttcctt gtgctaaatc
     3001 ctttccattc ttcataatac aaatattatc actcaattgt tcagcttctt caagataatg
     3061 agtagttaga aatatagttg tgccatactc atctctaatt tttaataaca tatcccacat
     3121 agattttctt gaatcgacat ccataccaac agttggttca tctaaaaata ggattttagg
     3181 agatgatacc atattcatag ctatgtccaa tctacgtttt acaccccctg aatatgatga
     3241 agtaggatat tttaagtaac tagataagtc aaacttatca attaaagagt ctattctttg
     3301 ttttgcaatc tgtggttcta ctttatacat tttactttga aataccatat tttccataag
     3361 ggataaatgt tcatcaatag agatttgctg tgctacacaa gcaatttgag tacgtatcca
     3421 agaaggatta tctactaaat cttttccaaa cattgttaca tttccagatg taggtttgta
     3481 aaaggtagtc aaaatattta taagagaaga tttaccagca ccattaggac caagtaaaga
     3541 aaaaatttct ccagcattta cattaaagct tagaccattt aaagctttca caccattttt
     3601 atattctttt actaaattgt ctatttcaat cgctaacata tattattcct cctctttaag
     3661 tggaaatatt atctctgtaa tatagttatc tgggtttcct tttatcaaca tacctggtcc
     3721 tttaataaat acttctctcc aaggagtttg tatttttata ttattttcat gaatatattt
     3781 aaatatcatt tcatacgttt ttggcaaatt actataagag cctgtgtgag taaaaaataa
     3841 agcttttgtt ttaggaaatt cttttgtagt tatacccata cgatttggag tttcagcagt
     3901 tggaacacat aattccattt ctgcaacacc agttttttgg tcaacatcat agtagcaaaa
     3961 gaatggtgca ccgttagact ttccttttat agctttaaat acatttggaa aatactttgt
     4021 tgcctcagtc ataggtccat tataacgcat ggtagccact gtgactgatt cgatattttt
     4081 gatttcaatt ttgcaattca tttgtttacc tcctaatgtg tgttcatatt cttactagat
     4141 ttttaagcat taatacatat aagattttga ttagttgaaa acatataatc ttatctcgtt
     4201 tgcttgtttt caagtctaac ataacataaa atatatatcc tctcatttga tgctccattt
     4261 tgtaaagtta ttatttaagc tttactttag attttttagc aaattaaaat aaagcaattt
     4321 ataaaataag tatttacaaa ttaagtgtat taatcgtata atacacttaa taggatacta
     4381 gataaagtct gaaataaagg cgtatttttt taaagtaagt gtactatcgt attaatacac
     4441 tagaatagga ggaatcatga attttgaatt agataataca actcccattt atttgcaaat
     4501 agtaaagtat ataaagagac aaatagtaac aggagagttg aaaccaggag agacaatacc
     4561 atcaagaaga gaaatggcac ttaatctaaa agtaaactta aatacagttc aaagagcata
     4621 taaggagatg ggtgatatga atataataaa tacttttaaa aattatcaaa gcagtgtaac
     4681 agttgatgaa aatatattaa aaaatttaaa attagagctt ataaatgaat cactatctgt
     4741 ttttatagaa gatatgaaag caataaatgt tagcaaagaa gaagttttaa aaataataga
     4801 agataagtat tagtttttta acaaatagaa aacttagttt agaaagttta tttataagca
     4861 tattggatgt ggaggatagt aaatatgata gaaataaaga atgtcagcaa aacatataaa
     4921 aggatgcaag ggcttaaaat aagaaagata gaagctttaa aaaatgtaag ttttaatata
     4981 gaaaagggaa aaataactgc attacttggt ataaatggtg ttggtaaatc aactatgtta
     5041 aaagcaatag caggacttat aaacattgat agtggagaaa ttcgtataga tggagaaaaa
     5101 ataaatgaaa aggtatacaa taaattggct tttgttccag atgtacaatc tcactttagc
     5161 aatacaacaa taaaagaaac atttgaattt atggaaattt tttattcaaa gtggaataaa
     5221 gaaaaatcaa aagaaatgat ggacatattt aaattggatg aagatgaaat aattgataac
     5281 ttgtcaaaag gaaacattgc aagagtaaaa ttaatacttg gattttgcca agacccagag
     5341 tacatacttc ttgatgaacc atttacagga attgatttgt ttaagaggga agagtttata
     5401 ggagtaatag cgcaatatat ggaggaaaat caagccatta ttataactac tcatgagata
     5461 gtagagatag aaagtttagt tgatgaggtt gtaattcttg atgaagggca gattataact
     5521 tcatttaatg cagaagaatt aagagaaaga gaaggtaaat ctatattaga taagatgagg
     5581 gaggtatata agaatgaata aacttctata tctaataaat gtagatttga gaagaagcaa
     5641 taagttttat atagcttata tatcattttt ttcattaatt acacttagtt taaatttatt
     5701 cgaaattaat aaatttaaaa attctaaatt tattatgaac ttagcaatag aagattttgg
     5761 aggtatattt tatggactag ggatacttag taatcttggt tttatccaaa gtatattgtt
     5821 ctttgggata ttgggacttt ttatatacta tatttttatg tggaaaagag agttcttttc
     5881 aaataatcaa agtatttata cacttatgat gttacctcaa aataagttta agatttgtat
     5941 atctaaatca atagccttga taacaatgat atatggtttt ttgataagtc agacagcaac
     6001 attatttata tgtaaatata tatttaattt catttttaga aatatgccta taatcaatat
     6061 gaactttgcc aaagatttat attatttaaa cttgaagagt ataccaattg attttatctc
     6121 ttttatggct atttatgtat ttttactact tatagctatt tctattgtaa attgctgtat
     6181 attatttatc ttttcctata taaataaatt ttatgtaatt ttaatcactt tgctgattat
     6241 agcaggctta tatttttcaa caatatatat aaatataatc actttattta gaaaatatta
     6301 taatcttata ggatttcaat ttaacaattt agtagcaggg ttattaagtt ttttaattat
     6361 aatgtttatt ctaaatggaa tatcttattt gctaattaaa aagaaagtat ctctttaagg
     6421 aggggtggta tgaaattaaa atctaaaata tctatattta ttatattttt gactttagca
     6481 atatatttta gtataggttt attaaataat gaagataatt taaagataaa aactataaaa
     6541 ggtgactcta atgaattaga ccatataaac ataaattttg gatatgcttt gaatggatat
     6601 ataaattcat attatacaat aaatggaagc aacaaaacca aaaagactga attaataaaa
     6661 ctacaaaagg atagtaagaa cacaaataat ttaattgatg tatctagtgg ttcagattta
     6721 attgctcatg ttggatttga aatgaatgag gagtcaaaag atataaactt tgtgatagat
     6781 gagaaaaaag aagatttaga aaaaggtgta tttccatcag aaggtagtga taaagaaatt
     6841 gaatatgaaa aattagatat gaataatttt acaaggacaa gatataaagt agataaaagt
     6901 acagatgatt attatgcaaa gatactagca tcaaaaagat ataaaaaata cttatatgta
     6961 tctgtacttt atgctacaag tgattcatca gaaaataaca aagaatattc aagtactata
     7021 gatataataa aaattaatcc agaaaataaa aaaatcaaga ctataaaaag tataaattta
     7081 agtaattatt tttccgaaaa ataccaaaac atagagaaca taggtgtaag ttatgctagc
     7141 aaatatgagg ataagatgta tattttagta aatgtactaa atacaaacat aggtgataat
     7201 agtaattcta aatttcattt acttgagtat aatcttgaag aaaataagga aagcataatg
     7261 gaattaaaaa ctgatagcaa aatggcttta gcaaaagcaa agttagaagc taataaatta
     7321 tatatggtaa tgtcgaatga ttatgataat agttcaatta cagagttaaa tttacttacc
     7381 tataatatat tagataaaag cttagatgaa gataaatatg ttttagataa tagagaaaaa
     7441 agaggaatta gaagtattga aattgattca aataaaatcg ttgcatatac atcaaggcta
     7501 aactctatat tatcttggga tgataaattt atgctatata taataaataa aaattctaag
     7561 gaaattgtat atgaaggaga attacaattt aacagttcaa atagtatgtt agaatttgaa
     7621 ataaagtagg tgagttgatg aaagatttaa taagattatt cgaatttgaa ttaaaaagaa
     7681 atataaagaa ttatatattt ataataattt gttgttgttc ttttgtaatt ttaaacatag
     7741 taaaaaattt aaatgactat aattacataa tagaaaatgc agttaaaagt gaacagttaa
     7801 caaaaatcgg aaatacgata gaaacggtaa atgttacagg tttctcaagc tttagaaata
     7861 taatgggttc tacagaatcg tggtttatgt ttggtataat tgcatgtatt tgctatgctt
     7921 tttttatttg gtatagagac tttaatggta gaagtaaatc tatatataca cttataatgc
     7981 tacctaaaaa tagaatcaat atttatatat ctaaattatt aaatatatta tttctagtgt
     8041 atagctatac agtagtactt acaatatctt tgtttattgc aagtaagttg ttgcctagac
     8101 atatgcttgg taatgtcaca aactatggtt ttgtacaaga aacaatatat gagttaaaaa
     8161 tgttacttcc atatagcttt gaaatactat ttgtagagta tatattttta ttgataggat
     8221 ttgtatctgt agtatttaca tcaattctta taaataaatc tatttataaa gtaagcactt
     8281 taataagttt tctattttta gttatagaaa ttttagtgtt tataatttct atagaattta
     8341 ttatacctta cgaatacagt gatgtattta ctgttctata ttcaagtata aacatatttg
     8401 tatgtagtct tatatctaat aaacttttga agcaaaagat tgacttttag gagggatatt
     8461 atgaaagcaa aaaatatagg aaaatataca atatgtttta taatagtatg ttttttaatg
     8521 attactatga ccttaatatt gagttatttt aataaggata aactatctgt aaaaacttta
     8581 aaaggcaatg taaaagatat agggagagta agtgtagtat atacacctaa tataagcaaa
     8641 ttttcttatg aggaggtaat tataagtaaa aatggagtaa gaaataatac aaacccaaaa
     8701 tcaagaatta gaaatgatta tttaaatatt gacaaaaaat acagtgactt tgttaatgat
     8761 aaaggaaaag aatttatata taaagatgat ttgaatatag gagaagcgta tacctctgtt
     8821 aagtctgatt tagtacaagg aatgaatgct ttaaatgatt gtataaaggt ttcaaataaa
     8881 aatttaaaaa gtggggtaga agaaaatttt gatattaatt taaataagtc tgattttaaa
     8941 gaaaatagtt ggaaaacctt atttaacaaa atatataaag gtaatttata tatggtaatt
     9001 agtgaaacta atatttcagg ttctaaagtc aataatattt gtatattaaa gatagatata
     9061 aaaaataagt cttataaatt attaaataga tttaatttag gattacagaa tggagaacaa
     9121 caaaatatca atgaaattaa attttctatt ggaagtaaat tatacttaga aatagtaaat
     9181 aataaaagta aaaatggata tattgaagga catgatagtt actctaactt tattatatat
     9241 gatatagaag ataacacttt taatataagt aataaattta tggataatct aaacaaagaa
     9301 aagaatgcaa atccaaagga gattggctta ttaagtaaaa ctaagctaga ttatatggta
     9361 aaaaacaata aattgaatct tatagttacg gatatgagta attccataac taatcttgtt
     9421 tatgatatta attctaatga gattaaatta gaagattatg agatacttga tttaaaagta
     9481 gattataatg aagcatcatc tggagttagg aaagttaagc tactggatga taagatatat
     9541 tctatttcag gtattaagaa cagtatatca ggagaattaa aaggatttaa agggattatt
     9601 gatgtagtcg gaactaagcc agtaaaattt caagtatttg atatgaaact taaaaagaat
     9661 atttatgaag ctgagctaat aaatggagat ataagtttac aagaaaagtt attttttgtt
     9721 gcaaattaag tgttagaatt aattttagaa ctttaaactt ttatatgtat cacagataag
     9781 tataagtaag ggagtgtctc aaaataaact ttttagctca tgagacactt tttttatatg
     9841 aaatcaaata tattttcatt gtttagattt attttgataa tgaaaaaaag attatcttta
     9901 ttttaagaaa gacatttatt tataattata tacaaaaata ttttttaatg tttttgtgta
     9961 taattataac aatttaattt atattaatgc acttaaattt gaaatagaat gcttatagtg
    10021 gtaaaattaa ttattagaat attagaaata ataaataaat aatacattgt acttaaaagg
    10081 gggagaaatt taagatgaac aaaaaatata ttaaagcagg gaatttaatt gatggaaccg
    10141 gaaatagtat tatgcaaaat aagggtataa ttattgatgg agatactata gttgaaattg
    10201 aagatataag agatgattta aatggatatg atgtgtacga ttacttagat aaaactgtta
    10261 tgccaggcat tatgaattgt catgttcact tgacaatgga gccagttgga aatccaaaga
    10321 tatattatga taatgtatca gatgtagagc ttgtagtaaa tacgataaaa caacttgatg
    10381 cttatttgga ttcaggagta acatatatta gaagcttagg ttgtcccaaa tatgtggatg
    10441 tacaacttaa aaatcttata gacaaagggt ctatagatgg tcctggtata gttacttcag
    10501 gtccagttat atgtatgaca ggagggcatg gatattattt tggtattgaa agtgatggag
    10561 tagatgaatg tagaaaatca gccagaacag ttttaaaaaa tggagtagat tgtgtaaaga
    10621 taatggcaac tggaggtgta acaactgatg gagttgagcc agggtcacca caattaactt
    10681 tggaggaaat gaaggctgct gtagatgaag ctataaaagc aggtaaaata actgccacac
    10741 atgcacaagg aagaactggt ataaaaaatg cagtgcttgc aggaattact tctatagaac
    10801 atggtgttta tttagatgat gaaataattg atttgatgct tgaaagagga acttacttag
    10861 ttccaactgt ggctgcacca tattttattc taaatgcagg aaaagaaagt ggaataactg
    10921 aagctactct tagaaagtgt gagattgttg ccattccaca caaagagtca ttcctaaaag
    10981 catataaaaa aggaattaaa attgcagttg gttctgatgc aggaacttct tataatgaac
    11041 atggaaaaac atattatgaa atgaaactaa tgtcagatta tggtatggat aatatggata
    11101 taatagttgc tgctacaaaa acagcatctg aacttttaag aattgataaa aattatggaa
    11161 ctctagaaaa aggaaagaaa gcagatgtta tagttgtaaa tggaaatcca gtagagaata
    11221 tagacgtact tgcagatgtg ttagcagtat ttaaacttgg taaaaaagtt agataaatag
    11281 tataaaaata aaaaagagtg tctaaagaaa tttttaaata attatagaca ctctttttta
    11341 ttagtaataa ttaaatcttt tatactttag aaaatagatt ctattttata tttagatata
    11401 actctttaaa atcattctta tgcaatataa tctatagaat ctacacatac aaagtatatt
    11461 cttgaatcat tagaatttcc aagtactata acatcatttt tcttacctag aacttcaaca
    11521 ccagttagaa ccaaactacc agctactaca gtaacttgat tatttatatt tgacatataa
    11581 agattatcta ggataccttt attacaacag caatcatcac aatcgcagtt gcaattacat
    11641 tctttgtaat gttttttatc aagatagtaa cctaaagatg ctatgaaatc ttcataatct
    11701 gcaggtgtaa tatcaaatgc aacagcttta agattacaca atgatgctaa atctacgttt
    11761 gctaatggag tagatgcagc aagtataaaa tcaattatag cagcaagtat tgcatctaat
    11821 atagccccaa ggtctatcgt aggaggaata actgcatcaa taagtgcaat taattcagct
    11881 actcctggta tagttcctat agtattaatt aatccctcaa gagttaaagg gactggaata
    11941 ggataagata ctctaccagc tatatctatt aaatcacagt tacaagcaga aaatctttca
    12001 aaagtaccat caagtccaga taaattatct tttggaggag ctgaaagatc tatacctacc
    12061 aaattagcac ctactataaa gaaatctgag ataaaagcaa attgattaaa gtttacaaaa
    12121 ggtcttagag catcatatct tagaagttct aatgcttctc tcatactttt tttacaacaa
    12181 cattgtttta ttttaggttc tttatattta tttggataat tatagtatct atcagctact
    12241 tgataatttt catagtatct ttcatttgta tttggataat cttcctcata ttcttgtgta
    12301 aatctaaagt cctctctaca tttattattt tccactaaat acactccttt tatattttaa
    12361 tttaaatgta tagataatta agcttatcta tatagtaata ttatatttat aatataaaaa
    12421 aatgttacaa aagatattat aaacgaataa aaaataataa tttgtcagat aaacttgtaa
    12481 atttttatga ataatccatt ctaaaacaa
//
LOCUS       DAYAKB010000096        12307 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.096, whole genome shotgun sequence.
ACCESSION   DAYAKB010000096 DAYAKB010000000
VERSION     DAYAKB010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12307
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.096"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            95..1357
                     /locus_tag="ACGI3L_003229"
     CDS             95..1357
                     /locus_tag="ACGI3L_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9198925.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            1377..2120
                     /locus_tag="ACGI3L_003230"
     CDS             1377..2120
                     /locus_tag="ACGI3L_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HFG9198926.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSKHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            2293..3678
                     /locus_tag="ACGI3L_003231"
     CDS             2293..3678
                     /locus_tag="ACGI3L_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9198927.1"
                     /translation="MENLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKYGFSIDELEGMDTAFAASYGEGRPVIAVLGEYDALDSLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            3897..4736
                     /locus_tag="ACGI3L_003232"
     CDS             3897..4736
                     /locus_tag="ACGI3L_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5685 family protein"
                     /protein_id="HFG9198928.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            4726..5169
                     /locus_tag="ACGI3L_003233"
     CDS             4726..5169
                     /locus_tag="ACGI3L_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198929.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            5180..5671
                     /locus_tag="ACGI3L_003234"
     CDS             5180..5671
                     /locus_tag="ACGI3L_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198930.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(5875..6603)
                     /locus_tag="ACGI3L_003235"
     CDS             complement(5875..6603)
                     /locus_tag="ACGI3L_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9198931.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            6728..7816
                     /locus_tag="ACGI3L_003236"
     CDS             6728..7816
                     /locus_tag="ACGI3L_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198932.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(8253..9101)
                     /locus_tag="ACGI3L_003237"
     CDS             complement(8253..9101)
                     /locus_tag="ACGI3L_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198933.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGIPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            9300..9665
                     /locus_tag="ACGI3L_003238"
     CDS             9300..9665
                     /locus_tag="ACGI3L_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFG9198934.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            9688..12075
                     /locus_tag="ACGI3L_003239"
     CDS             9688..12075
                     /locus_tag="ACGI3L_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFG9198935.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKAYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
BASE COUNT         4683 a         1255 c         2194 g         4175 t
ORIGIN      
        1 atgggaatat gctaagtgaa aaagtttact atggcttaaa tagatgagat tagacttgaa
       61 attttaaatg taaaaataaa tcttaggagg aaatatgaaa aaaattctct tagatacatt
      121 aaatagtaaa aaacaagaat acatagatta tttaaaagaa cttgtaagta taaagactga
      181 agatgttggt catggaatac taggtggatt tgaaaaagaa ggacaggaat atattgaaaa
      241 acttgcaaat tacataggtt ttagtgtaga tagacaagaa atgagcgaag aattaattaa
      301 aaaagcaaaa aatatatata aagaaggaaa tctaggtcac aattatcaag atagatataa
      361 tttaatttgt aagtatagtg atgatttacc tggtaagaca attgtattta atggtcatgt
      421 agacactatg ccaccaggtg atataagtaa gtggaaatat aatccatatc gtgctacaga
      481 agataatgga aaactttatg gacttggaac tgctgatatg aaatctggac ttatagcatc
      541 aatattagct gtaaagctta taaaagatag tggtctaaat gtacctggta atgtaaaaat
      601 aatgtcagta gtagatgaag aaggtggcgg aaatggtacc ataaatgcag ttatgaatgg
      661 tattgatgga gattgttgca taatttgtga accatcagaa caaaacttaa tagttgcaca
      721 tatgggattt gtattctttg aagttgaggt taaaggtgtg tctcttcact gtggtagtaa
      781 gtgggagggt gtaaatgcaa ttgagaaggc tatgttgttg cttcaagata taaaagagtt
      841 ggaacataac tggcttatga tatataaaca tccactatta ccttcaccta caataaattt
      901 aggtgtaata aatggtggaa cagcaggttc tactgtgcca gataagtgtg tatttaattt
      961 atgtgtacac ttcttgccaa atataatgag ttatgaacaa gttgtaaatg atgtaacaaa
     1021 tgtcataatg acaagggcta atggagattt atggcttaaa gataataaac caaatataaa
     1081 catatatcaa tcagggttag gttttgagat ggacaaggat tctgattttg tagtgaatgc
     1141 acataaaata ctagaagaaa ctctagggaa aaaattagag ataaaaggtt caacagctgg
     1201 caatgatgcg agattaatga aaaatttagc tgaaatacca acacttatat tagggccagg
     1261 ttcaatagaa caatgtcatt caattgatga atatgttgaa attaaggagt atttagatag
     1321 tatacttatg tatgcaagtc taatattaaa cttataaaag taggaggaat atataaatga
     1381 aaaaagtatt aatagtaggg gaatcttggg taaaaaatat aactcatata aaaggatttg
     1441 atacgtttgt tacaactcat tatgaagaag ctgtaaagtg gttgaaagaa gcaatagaat
     1501 ctggaggata tgagacagtt catatgcctg cacatgtagc agcagatagt tttccgtata
     1561 aattagaaga gttaaatgag tatgactgta taatattatc tgatataggt tctaatacgt
     1621 tcttattatc taatagtact tttatagatt gcaatagtaa tccagataga cttgaactaa
     1681 tcaaagagta tgtaaataat ggtggggcgt taatcatggt aggtggatat atgtcattta
     1741 caggaataga tgcaaaagct agattcggag aaactgctat caaagatgta ttaccaataa
     1801 caatgataga taaagatgat agagttgaaa aaccagcagg aataattcca gaagttattg
     1861 actctaaaca tccagtatta aaaggtatac caacagaatg gccaaagttt ttaggatata
     1921 acaaaacagt agctagagat aattgtcctg ttttagcaac tattggagga gacccatttg
     1981 tagctgttgg cgagtttgga aaaggaaaat ctgctatctt tagttctgac tgtgcacctc
     2041 actggggtcc aaaagaattt actgattgga aatactataa taaattatgg gttaatatgc
     2101 ttgattggtt aacatgctaa aaattttata aaacttgaaa acctcttact tgataaaatg
     2161 aaacttacaa gtcaagaggt tttattgtat aaaatggttg tatgatagaa aatattttta
     2221 aatcagttaa aattagtcat tttggctgat aatcgataag ttattagaaa cagggaggtt
     2281 tatataatta atatggagaa tttaaataaa aagtttttga tggaatatat agatgagata
     2341 cagggagaat taagagatat atcagataag atatggaaaa atccagaact tcagtataaa
     2401 gaatattatg cttcaaattt acaaaaagaa tacttaaaaa aatatggttt tagtatagat
     2461 gaattagaag gtatggatac agcatttgcg gctagctatg gagaaggtag accagttata
     2521 gcagttttgg gagaatatga tgctttagat agtttgtctc aaaaagtatc cactattaaa
     2581 gaacctattg tagatggtgg tgcaggtcat ggatgtggac ataacttact gggtacaggt
     2641 tcaataggag ctgtaattgc agtaaaggaa ttaatcaaac taaaaaagct gaaagggact
     2701 ataaaatact atggatgtcc agcagaggaa gatttatctg gaaaagtatt gatgataaaa
     2761 aaaggttttt ttgatggaat tgattgtgct tttagttggc atccatttga tataaatact
     2821 cctataagaa tcccaacact tgctaattac tctgtgaaat ttagatataa tgggattagt
     2881 gcccatgcag cacaagctcc ttataacgga agaagtgcac ttgatgcagt agaacttatg
     2941 aatataggtt gtaattattt gagagaacat atatttgata attgtagagt acactatgta
     3001 actactaatg gtggaaaaat gccaaatata gttcctgatt ttgcagaagt gtggtattac
     3061 ataagaggag ttaaaatgga gcatgtaaga gatgtatttg gtaggattgt tgatatagca
     3121 aaaggagcag cattaatgac tggtactatt atggaatatg acattataag tggagtatat
     3181 gactatattc caaatacaat attaacagat attctatcac aaaatatgaa attagtaggt
     3241 gtacaaaact ataatgaaga tgactactat tttgcagata aattagctga gacagtgtct
     3301 atagataaaa gaagtagtgt ttctagtgta ttaagtggaa ataaggatat tactaagatg
     3361 aatctgcatg atgaagttac ggatgataca tttactcata ataactgtat atcattatca
     3421 ttggatattg gagatgttag ttacataatt cctacagcac agtgttcttg ttcagtttgg
     3481 cctattggta tttctgccca tacatggcaa tcttgtgcca gtgcaggttc tgatatggga
     3541 tttaaagcaa tgttattggc atctaaatct atatcatgtt caataaatga tgtaatgctt
     3601 gatgaattgg ttataaataa agcaaaaaaa gaattgaagg atactgtagg tagttttaaa
     3661 tatataccaa ttatttaaaa cttaaattga tataagcaca actaacttgt atgagttaat
     3721 ataagtatat aatttaatat tatttttaac ccaaccttct aattatttta aatttaagat
     3781 acaatgatta gaaggaattt tttaagtttc ttagaatact gtaaattata taatcttgat
     3841 aaaaagtgtt atactatata taatctaaat aaaaaatagt acaaaaagga gtatttatgt
     3901 ttggatatgt taaaataaac aaaatggatt taacatttag agaatacgat tattacaaag
     3961 cttactattg tggactatgt aaatatttaa aaagaaatca tggagaaatc tctaggtttt
     4021 ctttgaatta tgatataaca tttttaattg ttttattaac agcagtatat aacccagagt
     4081 ctataagtac agaggaagtg tgtatagtaa atccatttaa aaagaaaaag gtaattacaa
     4141 atgatattac agaatatgca gcaagtatga atattctttt aacgtattat aaattggaag
     4201 ataatttaat ggatgataaa cgcataaaag ataaattggc atattatata tataaaaaca
     4261 aattaaaatt agcatatgaa aagtatcctg aaaaagcaga gtatataaaa caacaactaa
     4321 atgaattaaa taagttagaa aaagataaaa atataaatat agatgaagta tctagtatat
     4381 ttggaaatat aatgggtgaa gtatttgtct ataaaaaaga tgaaaatgag agaaacttaa
     4441 gaatgatagg ttttaatata ggtaagtata tatatctact agatgcctat gaagatttag
     4501 atgaagattt taagaaagga agatataatc catttataga gtatattgat aaaaatgatg
     4561 agttaaaaga aaaagtaaaa aaaataatag taacatcatt agggttttta gctaggggaa
     4621 ttgataatct aaatctaaat aaaaatgttg gaataataga aaatataatt tattctggtg
     4681 tttatttaag atatattaat atattagaaa gtagaggtgg aaagaatgta cagtaatact
     4741 tataataatg aaaattttat gagagcaaga gcattcatag aaaatagtga atttaaaaaa
     4801 gcatatgatt ttttaaaaac tttgactgac aaatgtgcag agtggtatta tttaactggc
     4861 ttttctgcaa tgaacatagg atattatgaa gaaggtgaag acttcttaaa aagagcaaaa
     4921 tttatggagc ctgaaaatag tgaatatagt gatgcactta gaagttatac acaatataga
     4981 aatgattata gcaatagggc tgacaattat aatagaagaa gacgtaatga tttagatgga
     5041 tgttgttgct gttgctgtga tgattgctgt tgttgtctag gtgacgattg ttgtgaaaat
     5101 tgtgctaagc tttggtgttt agattcatgt tgtgaatgtt ttggtggaga tttaataact
     5161 tgttgttagg atgataaata tgagtataaa agttgcttat ggaggagttt tattagcatt
     5221 aaatgtgata ttgttgactc ttacaaatat tattcctgta aatacattgt ttattatggg
     5281 gttagcatca cttttagtat caattgtaat aatggaatgg ggctttaaga gtggaattgc
     5341 tttttatata ggttctatag ttttaggatt tatagtgatg gcaagtaagt ctcaatggat
     5401 tgtatattca cttacctttg gaatatatgg tattgtaaaa tatcttatag aaaaagatag
     5461 gtctatatat attgagtatt ttatgaaatt agtatttgca aatataatga tacttatatt
     5521 gtatttttta ttaagaacaa tagtttatat tccaataaac atatttatta taggttcatt
     5581 tgagatagcc tttatagtat atgactatgt ttacagttct tttataggtt attacaataa
     5641 tagattaaga aagatgctat ttaaaaaata atagttgatt tttatattta attttaatga
     5701 aattgtagtt tagataagtg taaatgatat atatgaatat acattaaagc ataaagctaa
     5761 atttaatata ttctcttagt gcaacatata aaagctttga tttttagtca aagcttttat
     5821 atgttagata taaatattag atataatata agtttttaaa atagatagta taaattaaat
     5881 atccactata tttacatctg tagatagaga ataaataata tcttttcttt ctactattat
     5941 ctcaacattt ttagaaattt cctcatcaag tgatatttga gataaaagtt cctttgttgg
     6001 atttattgct attggatttc caactctttt tagcatattt atatcaccat tagtatctcc
     6061 ataggcatac gagtttgata aatctaaatc atactttaca acaaaatcgt ttatagcatt
     6121 attcttactt atagaatccc acattggaat aactgtgcct gtaaatatat tgttttcaaa
     6181 gacataatca cttcctaaaa aatcggttac attatatttt ttggccattt tttcaacaag
     6241 aaatccaggg ctaccagata taaatataac tatgtgtcct tgatttagat gccactcaat
     6301 ccttgaacgt gtgtatttat aaactctatc tgcttttaat ttaattactt ggtcacttgt
     6361 aaagttgata caggttttat ctaatccttt tagtgaatca acataaaggt cacatatttc
     6421 taatagataa tcatcataat taccttgtct tttatcccaa tccataaaag tgtctctagc
     6481 atgtttatac caattttttt ggtcaattat atcgtattta attaattttt taaaatgttc
     6541 aaccataaga gagtctctat aaagagtacc atctatatca aaaaaagctg ctatattttt
     6601 cataagacca cctcaattaa tcatttcctt atattatatt ataaattgta tctaagttgt
     6661 taaaatatat gtataataat ttatatatta aaaaacaagt attttagagt ttaaaggatg
     6721 tgactatatg aattttaatt ttgcaaaggc tacaaattct agacttatgg gcagtttagg
     6781 tcttataata aattggatag atgatgaaaa caatcacttt tgtcaatatt ttttattaga
     6841 tgcagaggga ttaggattag cggattatgt gagtttaaat aacccaacac aagaagaagc
     6901 ttatatggaa gaagaaagat tgatgggagg atttggttca gatagagttg aattaacgaa
     6961 ggatgaatct ttatttttag tatcttattt tggtaataag aatctttatt atgataagct
     7021 attgccagga gataaatgtg agtatattga tattataaaa aactataaaa cagatttaac
     7081 tatagaaaaa ttatacaata aaatatgtaa aagagttgac gaggaagttg aatttataaa
     7141 ctatatgacc atgagattta tagcatggga tagagaaagt ttaaagtact tttctggaag
     7201 tgacgagatt gcaaatatgc acattactaa tataaatgga acattactta aaaacgtggt
     7261 aagtgataaa ggtcaaggca gatatataag tgaagcttta tatgaagata atgatggata
     7321 ttatatatgt aaaattgctt tttgcataag taagtgttat gaaactggtt ttagaattaa
     7381 ttctctatta gtgacagata aagaacctat gtatgatttt gaggtatttg atgagatttc
     7441 taaaagtgaa tttgtaagtg tttacagtgt aaattcacct gaagaatttg caggagtatt
     7501 ttatagagaa aatccatttc tgttaaaaag taatatgaat gaaggtatat tctttactag
     7561 atttaatttt aataatgacc atgtaaaaga aaatgtatat ataataaata atgatatgaa
     7621 agctatatat tacttaatgg gaaataagtt ttttattggt acttataacg aaaatgattg
     7681 caattatatc aatgaaataa gtcaatctaa ttatagcgac tatattaaat ttgaagagaa
     7741 atttttcttt gagcaaaatg cattatatga ttttgcagaa tcaggttcat tagattttga
     7801 tgattttttg gaataataaa tttagacatt atttaagcga gattaactga atttaatctc
     7861 gcttaaattt atttctataa tattggggga atattatgag gaatacattt attattgtgg
     7921 tcaattatta aaattttata cagtttatta taaaaaattt atatttttct ttatgttgtt
     7981 tgccaatatt agtctcaaat acgagtatca tactattctg acccaccaat acaagagagc
     8041 atttttaaat gaaaaagtca gataaaatta aattttatct gactttttct atgtttatct
     8101 tattagatta tgttaatatc tgttgaccga ataagcgcat attcagtcaa ctttctatac
     8161 ctataataat attgggggaa tattatgagg aatacattta ttattatggt caattattaa
     8221 tgttttatac aacttactta aaaaaatata tattacattt cttcctcatc aaattcctca
     8281 atattagtag cctgtggtat accttgtata gacatattac tagaaccata aggagtagga
     8341 tatatattag gaggcatagt actaggcata actacaggca taccttgcat tgtattatga
     8401 catataactc ctggtatcat cataagtaca ttaggaggca tattttgatt acatgagaag
     8461 ttaggaatac ccatagtatt gttcatatta taccccatat tactgttcat gttattaggc
     8521 atacctgtat taccatacat attgttattc atattgccag acatattgtt aggcataccc
     8581 atattactat tcatattatt agacatattg ttaggcatac ccatattact attcatgtta
     8641 ttaggaacat tgttaggaat gcccatgtta ctattcatat tattaggcat attgttaggc
     8701 atacccatat tactattcat gttattaggc atattgttag gcatacccat attactattc
     8761 atattgttag acatattatt aggcataccc gtattattat tcatgttatt aggcatatta
     8821 tttgtagcag atgtattgta attcatattt ccggatgtat tatttgtgtt aggcaagttg
     8881 tttggagaat tactactttt aggataatga tttacattat taggatatag gttatttatg
     8941 ttctggttat taggtatttt tgtataacca ttagaaattt gagggtcatt tctcaattca
     9001 tcttggggaa tttcttcatt agtaatataa tctgcatagt tcgctgggtc taagtaaggc
     9061 atgtaactag tatctaaatc cttttttttc ttgttactca tattaaactt gcacctccta
     9121 gaaaactata aaaaagttta caaaaactta ttctaataat atatatatta aaaaagttta
     9181 taatatgtgc attctattta tattaaatta ataaaaatta ttgttgcaaa tttagaaatg
     9241 ataacatata atgaacatat gaacagttat tcatatatta aaataatgga ggattaaaaa
     9301 tgagagaaga gataaatgat tgtaattgta atatagtaca tgaagaaata gtaacagagg
     9361 ctaaatcaac tatgccagat gaagaaatgt tatatgattt agcagaatta tttaaagtat
     9421 ttggggatac tactagagta aagatattat atgcattatt tgcaaatgaa atgtgtgtat
     9481 gtgatatagc gagtttatta aatatgactc attctgcaat atctcatcaa cttagagtat
     9541 taaagcaggc tagattagta aagtttagaa gagaaggaaa aacagtgtat tactcattag
     9601 atgatagtca tataagtcag atatttgatt gtggattaaa tcatattaga gagacttata
     9661 aatgataaat gagaggagtg aatatatatg gaagcaaata attcaattaa aaaagaattt
     9721 atactaggag gattaaattg tgctcactgt gcagaggaga ttaataataa agtttctaaa
     9781 ctacaagaag ttaaatcttc caatttaaat tttataaata aaaaacttac agtaaatata
     9841 aaggaaagtt ttaatgagga tactactata gaaaagataa tagatataat agattcaaca
     9901 gagccaggtc ttgatataca aataagttct aaagaaaatg cagctagtaa aacatcaatt
     9961 aaaaaagagc ttatattagg aggattaaac tgtgctcatt gtgcagaaga gattaataac
    10021 aaagtttcta aattaaaaga agttgaatct tctaatttaa actttgtaaa taaaaaactt
    10081 acagtaaata taagtaataa ctttgaagag gatgatgtta taaataaaat aaaagaaata
    10141 ataaattcaa cagagccagg gcttgatata caagtagggt ctactgacaa agtaaaaggg
    10201 agaactactg aaaaatcagg agctgtaaat gatacaaata agaaagaatt aattccactt
    10261 ataattggag cacttgtata tatatttggt atatatcaaa cagctacagg ttatgaaagt
    10321 cagtttagca atatagtatt tatagttgcc tatgtaatag taggtggtga tgtgctttta
    10381 agagcaataa gaaatatatc aaaaggaaga gtatttgatg agaacttttt gatggctcta
    10441 gcaacagtag gagcattagc aataggggag ttatcagaag cagtaggggt tatgcttttc
    10501 tataaagtag gagagtattt acaaggtgtt gcagttggta aatccagaaa gtctataact
    10561 tcacttatgc aaataagacc agactatgca aatctaaaag ttaattctga agttaaggtg
    10621 gtgtcaccag aagaggtaaa tgtaggtgat ataatagtag taaaacctgg tgaaaaagta
    10681 ccattagatg gtgtagtagt agatggagtt tctatgttag atacttctgc actcacagga
    10741 gagtcagtgc tgagagaagt tgaaaaagga gatgaaatct tatcaggtgt tataaataaa
    10801 aatgctttat tgagtattga agttacaaag agttttggag aatcaacagt ttctaagatt
    10861 cttgaccttg ttgaaaattc gagcattaaa aaatcaaaga cagaaaactt tatatctaag
    10921 ttttcaagat actatactcc aatagtagta atagctgctt tattaatagc atttgtgcca
    10981 ccacttgtaa tctcaggtga ggtatttagt gattggttat atagaggatt gatattctta
    11041 gtcgtttctt gcccttgtgc attagtttta tcaataccac ttagtttctt tagtggaatt
    11101 gggtttgcat ctaaaaatgg tatccttatt aaaggaagta actatttaga agctttaaga
    11161 agtgtagata cagtagtatt tgataaaaca ggaacactta ctaaaggtgt gttcaatgta
    11221 actaagttaa atcctgaagg tatatcagaa gaagaattat tagaatatgc agctattgcg
    11281 gaggtaaatt caaatcatcc aatagcaaag tccatattaa gttactataa taaaaaaatt
    11341 gatttagata caatagacag ttatgaggaa atagcagctt atggaattag agtaaagcat
    11401 aatggcaatt ttatattagc aggtaatgag aaacttatga aaaaagaaaa tatatcttat
    11461 tcatcagcta aagaagtagg cacagtagtc tatattgctg ttgataaagc atatagaggt
    11521 tatatagtta tctctgatga agtaaaagaa gatagtaaaa atgccataag aagcttaaaa
    11581 gaaatagggg taaaagaagt tgtaatgtta actggagata atgagaaagt agcaaaaaat
    11641 attgctcaag aattagaatt ggatacagtt tactcaaatt tacttcctaa tgaaaaggta
    11701 gatagattag aagatttata tgaaggaaga actgaaaaag agaaaatagc atttgtaggt
    11761 gatggaataa atgatgctcc agtattagct cgtgctgatg ttggtatagc tatgggaggc
    11821 ttaggttcag atgctgctat tgaagctgca gatgtagtgc ttatgacaga tgagcctagc
    11881 aagatatcta aagcaattga aatagcaaac aagactaata agatagtgtg gcaaaacata
    11941 atatttgctc taggagtaaa aattatagtt atgatactag gtgctggagg agtagctact
    12001 atgtgggaag ctatatttgc tgatgtaggt gtggcactta tagcagtagt aaatgctatg
    12061 agagctatga gataagggat aaatgtaaat ccatactatt taaaaaactt ataattatat
    12121 attgaagtat gtaataatga aaggtatcaa taagtttctt ttaactttat tggtaccttt
    12181 ttattggagc gctttgcata tataaattta tattcattat ccattatgtt tatttaatgt
    12241 atttatttag tgtagagctt ttatattgta attttaaaat ttagacatag aaggtttatt
    12301 aataagt
//
LOCUS       DAYAKB010000097        12143 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.097, whole genome shotgun sequence.
ACCESSION   DAYAKB010000097 DAYAKB010000000
VERSION     DAYAKB010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.097"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..2103)
                     /locus_tag="ACGI3L_003240"
     CDS             complement(<1..2103)
                     /locus_tag="ACGI3L_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9198936.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIG"
     gene            complement(2093..2845)
                     /locus_tag="ACGI3L_003241"
     CDS             complement(2093..2845)
                     /locus_tag="ACGI3L_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9198937.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(4111..4287)
                     /locus_tag="ACGI3L_003242"
     CDS             complement(4111..4287)
                     /locus_tag="ACGI3L_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198938.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(4391..4972)
                     /locus_tag="ACGI3L_003243"
     CDS             complement(4391..4972)
                     /locus_tag="ACGI3L_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9198939.1"
                     /translation="MKADSTKEQLINATIQLLSSHRDVSSITAREIVAKANVNLAMIN
                     YYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFDFIGEHSQFI
                     KISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSFIQLLFLRSN
                     AFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(5098..5922)
                     /locus_tag="ACGI3L_003244"
     CDS             complement(5098..5922)
                     /locus_tag="ACGI3L_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9198940.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(6100..6993)
                     /locus_tag="ACGI3L_003245"
     CDS             complement(6100..6993)
                     /locus_tag="ACGI3L_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFG9198941.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(7250..7687)
                     /locus_tag="ACGI3L_003246"
     CDS             complement(7250..7687)
                     /locus_tag="ACGI3L_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFG9198942.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSIPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(7944..8093)
                     /locus_tag="ACGI3L_003247"
     CDS             complement(7944..8093)
                     /locus_tag="ACGI3L_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HFG9198943.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(8106..8336)
                     /locus_tag="ACGI3L_003248"
     CDS             complement(8106..8336)
                     /locus_tag="ACGI3L_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HFG9198944.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(9195..9416)
                     /locus_tag="ACGI3L_003249"
     CDS             complement(9195..9416)
                     /locus_tag="ACGI3L_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HFG9198945.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            9996..10253
                     /locus_tag="ACGI3L_003250"
     CDS             9996..10253
                     /locus_tag="ACGI3L_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFG9198946.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            10722..11960
                     /locus_tag="ACGI3L_003251"
     CDS             10722..11960
                     /locus_tag="ACGI3L_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HFG9198947.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYITYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         4498 a         1446 c         1645 g         4554 t
ORIGIN      
        1 accaataatt tttttgaatt tcttataagt taatagatat ataaggtaca tataaacccc
       61 acaaatccct ataaaaccta agtttatcaa aagagcattg acctcactat tgacgattct
      121 accatcatta tttaacataa tcataaaatt aaacagataa attaaaaaac ttcctgcaat
      181 aagagggtat gaaaatactt tctttaattg atttctaata cagaacttta tataatcatt
      241 gtttgctcct aatcgattta aatccataaa gacctgcttg tgatttatag ctatagtaac
      301 accccttgta tatgcaatga ttcctactgc tgtaaaacat atgattgcca catatatgaa
      361 taacattaag aagactgcca tgttttttat catatcttgg ctttgtaaaa ttttaaagtt
      421 aggatagtat ttccaattaa gatacaactg attgttgttt gggtctagtt ttaaatgacc
      481 ttcaccactt ggatattctt catccataaa atattttctt ccagttgatt cataacgttt
      541 ttttacgtat tcatcataac cactgaacat gcccatttcc ttagatgttc tttttataat
      601 ttctttcttt aagtcattgg caaaagcata ggtatcttta tctacattaa atagtataga
      661 attattgtaa ttttttatgg ataaatcttt agtaaatgat ttataatcct cctcattaag
      721 gacataggcg ttcatacttc tattttgaaa aaaagaacca ttaaatatta tttttccagc
      781 atatctaaag gggatttctt tttctgtgac tgggcttgat ataaatttgg tatatttata
      841 atcttgattt tcatttcctt tatttacaac agcaagatat tcaccatttt ttatagttat
      901 tggtttgcca attagcttgg aaaaatcttt ggaattaaag aacatatcat aggagctttt
      961 tttcatatat accttttcga tagttccatc tttatgatat attgattcta caccatcaac
     1021 aattaattct atagaaggaa tttccatata gttttgaatt tttatattgt gtttatctgc
     1081 taattgttca atatcttttt ttgatacctg tttatctctt tgattgtagg taaaagtata
     1141 atctataggg ttatttttaa gagtatcata gatacctgta accatattag gaacatagaa
     1201 tacagcaaat aatgctcctg caatcaaaaa tgaaataaca cacatgtttt ttactgtttg
     1261 tcttcccata aatctcatca tgctagttga tatgatgttt ttatagtatt tctctggatg
     1321 ttttcctctt ttagcatgta caactatgta tgtcataatc atatatattc caataagaga
     1381 gagtagataa gtaaagctcc atatagatgg tagtttataa tttaatttgt ttatagttag
     1441 tgaaggtacg agatatccta gaaaaatacc gagtataata aaaattatac ctaatatacc
     1501 ataccagtcc tttacatcct gtattggttc agatattctc tggtcattta atatatcaat
     1561 tatatttgta cgattaataa attttacaga aagtataaat atgcataatg tcacaaatac
     1621 actaaatata aatccatata tgaatccttg agttccaaaa tgatatgtca tttctctggt
     1681 atcaataatc actaattgaa atattttcca tataccaaaa gatacaggaa tacttaatat
     1741 aagacctaaa aaacagcata ctattgaaat taacaatatc tctgaaaata gaagtttttt
     1801 taatttcttc ttatctgttc ctagagccat gaaaatacca atttccttgc ttttaaattt
     1861 taaaaagagg gaagaagcgt atgtagtaaa gacagcgcat cctaatatag caactgagaa
     1921 tatcattgta gcctgttttc tgctatctcc accagttgga agtatgtttt gtattgttgg
     1981 gctaaaataa attagagcat atgaagttac taataccaca gaaagtatta tacaaaagaa
     2041 taaagttgta tagttcttcc aattataggc tcgaagttta ctgtataatt tattaattgt
     2101 catcttgagc gcctcccatt tcttttaaaa cttctagtaa ttcatctagg aatttatgtc
     2161 ttgaatttga ttttacaact tctttataaa ttattccatc tttaagcaca ataactcggt
     2221 cacagaagct tgctgcaaag ctatcgtgtg taaccatgag tatagtagca tctaattctt
     2281 gctttgcttt taaaaatgat tcaatgactg tacgacaaga cttactatca aggttaccag
     2341 ttggttcatc tgctaatatt aaatctgggt tgttcatgag tgctcttgct actgctgtac
     2401 gctgtttttc tccaccagat atttcggcag ggtatttttt tctgatatgt tcaataccaa
     2461 atagctcaca tagattaatt gcacggtttt ccatttgtaa gacttgacta cctttgataa
     2521 tttgtggaac acatatattt tcaaagacac taagaccatc aaatagcatg aagtcttgga
     2581 atacaaatcc tagttgttga tttctaactt ctgaaagttc cttttctttt aaatttctta
     2641 tattattatt tccaagaatt atttccccat tatcaattgg gataaaacat gaaatacaat
     2701 ttaaaagagt agtttttcca cttcctgatg aacccatgat tgcgacaaat tctcctttgt
     2761 tgatttcaaa agaaatattt tttaatacag gatatgtttt actgcctgtt ttatatgatt
     2821 tacataattg gtttacttta agcatatata tcatcctcac tttcatttat cttgtaagtc
     2881 aatgatagca tttgaaaggg gaggagggat atgagctata ttgtaatagt tggatgtttt
     2941 tttgtaatgt ttgaaaatat attgtttgga tagtgtgaga ggttattatt atagttaaat
     3001 tgattatatt attggaggat ttagagggtt atttttaggt attaattgtt gtgctaaagt
     3061 aatatgatgt ggaacattga aggtgtaatt agaaaagaag tatatagtaa aagtaaaaag
     3121 gttatagaat aacgaatgtt gtattgaaaa aaatgatgta aataatgtat agtagggtta
     3181 aaaagaaaaa aagaattata gagcagtaag attatttaat ggaatgtatt gtaaataatt
     3241 tgaaaggatt taggggctat taacacaatg taattgagaa aatatattgg agttttggaa
     3301 ataaataggt tgttagaaac aattgaaatg tataataaaa aggttaaaaa gtattattag
     3361 tataggtatg atagataatt ttagaaagtg gaagtatttt agactatgct gaaaagtgat
     3421 tgatatgatt ttgagatatt aaaatattac tatattatag taaagaagtt aaaataataa
     3481 aatgttgtaa taataaaggt ttgtagtata ataaagaact gtaataaata agactttgca
     3541 atgtaataga aatgctgtaa taataaaagt ctgtagtata ataaagaact gtaataaata
     3601 agactttgca atgtaataga aatgctgtaa taataaaggt ctgtagtata gcaaagaact
     3661 gtaataaata agagattgta ataataaaag tctgtagtgt aataaagaac tgtaataaat
     3721 aagactttac aatgtaatag aaatgctgta ataataaagg tctgtagtat aataaagaac
     3781 tgtaataaat aagactttac aatataatag aaatgttgca ataacaaaac accataataa
     3841 ataagagttt gcaatataat agaaacactg caataaataa gagatttcaa tataataaaa
     3901 gtctgtaata taacaaaatc ctataataaa taagatttta caatataata aaaatcctat
     3961 aataaatagg actctgtaat ataataaaat gctgtaacaa caaaacacta taataaataa
     4021 gaccctgtaa tataataaaa atactataat atagtaaaaa tcatgcaata ataaaaatct
     4081 ataataataa acctcagcat aacaaagaca ttaatttctt actaaaaagg ccaccacaat
     4141 taacagtgaa aaagcaattg aaagtattga aaaagtaaag tgagaattag agtcattatt
     4201 acgattatta agttttatcc ataaaccaca tataattgta cacaacaata aaattgctga
     4261 tattactcct ataaatgtaa aaaacattaa aattcctccc ccttatttaa tgcaagtatt
     4321 tttagtcaat gagaatattt tcaaacgtta ccataaaata aaaaaatgta cataaaaaat
     4381 taatatagta ttattttgta atatctacca ataataaatc taattgaaaa tctattaaac
     4441 catttctctg ttcaatatta agaatatcaa taccactata cttgaaaaaa gcattagaac
     4501 gaagaaaaag caactgaata aatgaagtta tttgatacgc aatagttctg tattcagctt
     4561 cagttttttt gttattctga ttttcatagt gagccttaat taaaggtagt atctcaaatg
     4621 gataaacaat ttcttcctgt atcaatatat agggtacaga aatctttata aattgactat
     4681 gttcacctat aaaatcaaaa aatgcaatta gtatttccct taattgctgt ttaggtgcta
     4741 aatttttagt atcatgtgta gccttatatt catccatatg acgctttaaa aattttttaa
     4801 tagaaatatt aattaactcc tctttagatt taaaataata attaatcata gctaaattga
     4861 catttgcttt agctacaatt tctctagccg taatgcttga aacatctcta tgtgaagata
     4921 gtaactggat tgtggcatta attaattgtt cctttgttga atctgctttc ataatttttc
     4981 cccttaaaag tttctccata aaaaaattaa acatgtttaa tacacgttta gatactatca
     5041 tgaaaatttt gggatgtcaa tgggtgatta gtacttaagt atttaagtac taatctatta
     5101 gacttttata agggggattt gaatttctgt aagataattt tcaggattta tttcattatg
     5161 ttcaccttta tgtccgattt gtctatttat acctgatatt tgataatcac tatttttatc
     5221 taaccaataa cagaacgatt catatgcacc agctatattt tcatatggac cataaaccat
     5281 agtacatgcc atcatatcaa tttcttctgt ctcacgatat ataaatccag atttgttctt
     5341 tccaatcttc tttacaacca ttccaacttc aatatctaca ccattatctt tgacttcttc
     5401 atcatggtaa aaagctatgt tattgttgga ttgacgtgat acttctatat gttcttcttt
     5461 gataaattta gatagctttt cccagagtat accttcagat tggtagtctg gaattatctc
     5521 tctaagtgat atgattttat aacttggaat ctttttaaag acaacattgt aatgaatttc
     5581 atctttatca cagtttatag cttctataaa tttatcaatt ttatttattc tttgttgttc
     5641 ctgctttatt tccttttgta tttcattctt ttttctattc aattccttaa ttacaaattc
     5701 atcattccaa ttatgtacga tatttgctat ttctgcaacg ctaaattttg aatctctcaa
     5761 taatacaatt ctttgtaata ttgaaatctg ttcaactgag tataatctat gacctgtata
     5821 tttgtctgtt tttgcaggtt ttaaaatacc aagttcatca taataacgca acatacgaat
     5881 agaaatttgt gttagttttg aaacctctcc tattttaaac atgaaaatat gacctccttt
     5941 tcacttataa tcagtatata ttttgttttt atatacttca agcgtttgtg gaaatacaat
     6001 tattttccag atgttgcaat aaattataga gagtaaatta tatttaagta gtaatcgtat
     6061 caaatcatag attatcttaa tttataattc atattaaaat taccagtcta actcaaattc
     6121 aaaatcatcc gactttatct gttcaatttc agaatttacc ttctgtttaa atttattaga
     6181 agaaatcata tatacaagaa atattaaacc aaatattatt tgtacatatt gagctattac
     6241 acataattta atagggtagt gtagaagtaa ttgaatgttg aaaaaatagt acatcatatg
     6301 aactaatcca gctgataaaa tgcttctact tgtattgata tatacaaaat taattataaa
     6361 gtttaaaagt acaatgtttg gtataaataa aaaagcatca aatagggagt attgtgccaa
     6421 attatatggt atttgattag gtgtaaaata cgaccctaga taccagattc cacaaacaag
     6481 ccctaaaata attgaagagc ctataaatcc aaatctaact aataatttgt caatggcata
     6541 tcctctccat ccagcttctt gactaagtat actcaatata aaacttgcta atagcatata
     6601 agctatttta gaaggtctaa acactgctat gtgtatccaa tctatatcag aagtttttac
     6661 attaaagtaa tttccgatta ttaacgaagt aataaaagtt aaagcaaaaa ataatattgt
     6721 taatagtatc cattttattc cgatttcttt aaagcttagg tatctataaa taaaatcttg
     6781 ttttgcactt tgtggataga ttgtagaaat aaaaaataga cctacaatag ctggtgatgt
     6841 atatgcaaga taaaaaatga tttctccaag tattgtattt gtaattccga gcaacgcagg
     6901 tgtaagactg aatatccagt tcaatactag agtaaatgta aagaaataga ttaagtgttt
     6961 gtttgtatta aagggggtgt tatatagttg cattttttca ctatccttcc gttttataat
     7021 gaagttttaa tttttattaa ttgtttattt atttttatat gtattaagtt atcgcttgat
     7081 gttagttatt gcctataata atatcctatt ttttatattt tgattaatta tttttacact
     7141 aaatataatt aattagtatt taatattgaa tatattatat tattattaat tattaaatag
     7201 gtcaataaat ttgcaattag tgatattaat aaattacttt agatttttat taaatgttta
     7261 gcttttcttt aatatttttt atataacgac gatttataat aactttttcg ttgtttttta
     7321 aagtagcttg catgcgatta tgtgatatta cttttatact ttttatgtag tccatattta
     7381 aaatcatgga tttagatatt cgtgagaaag atgtattagc taataatttt gataatttat
     7441 atatttttaa atcaatttca aatacatcat cttcataata agcaaatgtt ttatttccaa
     7501 ctgtctcaaa gtataaaata tcacagacat tgagtttata aatctctcct gattttttac
     7561 cttttatatc aagtaacggt atactcaata atgaaattat tttttcaatg ttattatcta
     7621 gagcagaaca ttttatggtt atttcaatat catcacaatt aataccttgt tcgacatgta
     7681 ttttcattaa tcatcacctc attttattac tgtcattaga atagcattat atcttattga
     7741 gtccaactag atgcgttcta aatttcaaat taagcatagt gaaattcaaa aataaaacag
     7801 tgaaattcaa atttgaggtg gtaaaattca aaaaaatact atggatattt ggataaatta
     7861 tccaaatatc ctagtatttc acatagaata tgtctaatta ttttacaaat agacctattt
     7921 tatgacttac atatattgtc aaattacttc ttaaatatca aaatattttt ggataatgta
     7981 tcaatactgt ttgataaagt atttaattta ccctcaattc taaccaacaa gtacatggat
     8041 agagctatag gaaaaccaac attggttatt aacagttgta aactatcatc cataaaatta
     8101 gccccctatt ctataactaa gtcataagga gtggtatttg tttccacaac cttggcttca
     8161 acaacagaag ctaggtcaaa tcctccaacc gaaaaaatat ttttagatac tatcaaatcc
     8221 atgacagatt ttatattttc ttcagttaaa tcatcctttg gattttctat agaaaaagaa
     8281 acttgtttat cctttacatt tttaaagctc atgactaatt ttttcttaat ttccatataa
     8341 ttacctccga tataataatt tatattttaa ttgtttgctt gttaatattg gtattttaat
     8401 tatcaatatt aatgttttgc ttgttagtat taatatttca attgtcaata ttaatgtttt
     8461 gcttgttagt attaatattt caattgtcaa tattagtgtc ttgcttgtta gtatcagtgt
     8521 ttcaattgtc aatattagtg ttttgcttgt tagtattaat atttcaattg tcaatattag
     8581 tgttttgctt gttagtatta atatttcaat tgtcaatatt agtgtcttgc ttgttagtat
     8641 taatatttca attgtcaata ttagtgtttt gcttgttagt attagtattt caattgtcaa
     8701 tattagtgtt ttgtttgtta gtatcagtgt ttcaattgtc aatattagtg ttttgcttgt
     8761 tagtattagt atttcaattg tcaatattag tgttttgctt gttagtatta gtatttcaat
     8821 tgtcaatatt aatgttttgc ttgttagtat tagtatttca attgtcaata ttagtgtttt
     8881 gcttgttagt atcagtgttt caattgtcaa tattagtatt ttaattgttg actctagtta
     8941 ttgctgatat agaaaatatt taatttattt caattaatta gattaaagta gggtagcatc
     9001 taaaatagct aacatgttta agttgaaata cgtttaatat attaattttt caaagcgtta
     9061 atatattaaa gttataacca aaattgaagt tataatctgc caaatctata gcgtattaag
     9121 tgcattatat aacttaatct tttatataaa gagttaattt tttaatttgt aaagcagagt
     9181 acgtttaaaa gacactattt agatagtgat gtactatcta attttaaaat atctacaata
     9241 gggttctctt gaagacttgc tattgcttct gcaacagcat aaacatcttc atttaatgcc
     9301 tctgctttta catttgcaaa tgatttactt ttaacaactg ccttaccctt atcatcaaaa
     9361 ccagcatcca attttagttt tatactagat aaattttttg ttgaaacaac ttccataaaa
     9421 ttacctccta aaaatttaat ttcaaagatt tgtcgacttt ctttgttagc tataatacta
     9481 tcatctaaga taatatcgga gttaaacagt aatttctaaa gattttttgt gtaaattttt
     9541 ataggaaaaa ttttactttt ttgctgatga aaaagtttac aagttatttg tgaagatatg
     9601 ttcttagtgt tttgaaatag tatttgtata tattcatgct tagttgagat agttttgtat
     9661 ggattttcat atgtgtagag ttaaatgtta ggtactaaag tttatgttaa attaaatgtt
     9721 aaagcttatg ttaaaaattt tattaaattt aatctgtaaa taaaaaagtt aaaagtccaa
     9781 tattaacatt ttacttttaa accattaaaa tctttattaa agctaacaaa gttataagtt
     9841 atgagaaatt ttattgaagt taatacaaaa attaatttta aagctaagaa attttttatt
     9901 agattcaata aaactaataa atatagttta gtcaataatg tattaaataa aaactttgtt
     9961 aagtctataa aaatatctta aaggaggtgt aacttatgaa gataaaagtg gaggatatac
    10021 cagttcaatt tcatgcaatg gtagaaataa tcggaattga taagttcata gaggttgcca
    10081 agttgtatgg aggaacaaat acttatatac ctacgtataa ggggcttttt agatatgcta
    10141 gaaataggga tatagtaaaa caatttaatg gagtcaacca caatgaattg gctattagat
    10201 ataatatgtg tgtaagcaat attaagcgaa tactcaatga aaatagtgtt taaatataat
    10261 aaaataatgt ttaaacataa tgaaaatagc cttgttaaac gtaagagtaa agacaaagaa
    10321 gatgttttat aaagtttttt tagacaaatt aactaaattt actacttatt aatttaaata
    10381 cattgtatat tctataaaaa aatttgttaa atactggaga tatattgaga atacaaagaa
    10441 aatggtcgaa aatatttgtt ggctaaaaaa tagataaaat gatacaattg cttgtataaa
    10501 ggggaaaaat aaataaataa actatataaa taaagaaata gcaattaata tgacataata
    10561 tatttataaa attaagaata taaatagata ttttaaggga ttagttgtta aattaggaaa
    10621 tattaaaaaa aatatatatt tatatttaaa ctattttgtt atttatataa aaatacttat
    10681 ctagttacta gcaattatta gtagaaatgg gggaaataga gatgaataag ggattttaca
    10741 aattaaattc agtggtattg aactttgata ttaagaatga tgttaacaag ataagattta
    10801 atcattatat aatgagaaaa gaaaacatac aaagacttca aggaactctg ccaaacggac
    10861 aattttatat gacagtgaga agagctgcta cagatttaca actttctatt tctactataa
    10921 gtaggcttgt aaaagagttt ttggatttag ggataataag attagtgtct aagggtgtaa
    10981 aaggtaatcg ttctgtatat agttacgtaa gtatagagtt taatggaagt ttatttgatg
    11041 atagtaaata tatggaactt gactgtgtat gtaatgatga atttattgat aatagtggca
    11101 tagagtttga ttgtgatagc aaagataatt cttttaatgg agatataaat gtagaaactg
    11161 tgcattgcat taatgagtat ttctctgatg atgatgtaga gcataattat aacaatttcc
    11221 ataacaaaga tactataaag gataaagcca tttctaatat tagcactatc aaaaaatata
    11281 ttgatgaatc ttttgataca aataaatcag aaaattctaa cttacaacag gagtcaataa
    11341 atttcaactt taatgataca tgcaatgaaa tagataaaag aacgaataat agtatagaaa
    11401 ataatcaaaa taaaaggcct atgagattga gtgacatcag tcttttaagt gataaaggta
    11461 tgacaaataa aaagaattac tttaatcata atcatggtat acaaaaaggg actaaatctg
    11521 taacaaagaa aaaagaatcc ttaaataaat ttaataaaaa aaatatacag caaagcatta
    11581 taaatatgct aaataaaaaa tcaggtaaga attttaaaat cgattctcca ataagcataa
    11641 aacttatcaa tgaaaggcta aaggaaggct atgtcttaga agatttctac aaagttattg
    11701 aggtaaaagt ggctaagtgg aaaaatacca taatggaaat gtatataaga ccagaaactt
    11761 tgtttagcta taagtttgaa tcctatgtaa atgaaaacat atctatgaaa agtcaaagta
    11821 atgttcaccc atgtaaagaa ggcaatagta atgatagcag taattatata cattctgatt
    11881 atataacata tgatggcagt gtgcgtgaga gaaaaaaata tgagaatgta agatactgga
    11941 atcctatatg tgaaatttaa ttagtttaaa aatgtattta tgataaataa gatattaata
    12001 gagaatagtg agctatagca aatgatatat caatagttgg tagtaagtta tattaagtaa
    12061 gatattacta tcaggtagtg aattatattg aacgatatat taataattgg cagtaagtta
    12121 tatcaaataa gatattacta tag
//
LOCUS       DAYAKB010000098        12055 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.098, whole genome shotgun sequence.
ACCESSION   DAYAKB010000098 DAYAKB010000000
VERSION     DAYAKB010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12055
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.098"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            201..1067
                     /locus_tag="ACGI3L_003252"
     CDS             201..1067
                     /locus_tag="ACGI3L_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9198948.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            1259..1456
                     /locus_tag="ACGI3L_003253"
     CDS             1259..1456
                     /locus_tag="ACGI3L_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9198949.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            1459..1902
                     /locus_tag="ACGI3L_003254"
     CDS             1459..1902
                     /locus_tag="ACGI3L_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198950.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(2089..2176)
                     /locus_tag="ACGI3L_003255"
     tRNA            complement(2089..2176)
                     /locus_tag="ACGI3L_003255"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2140..2142),aa:Leu,seq:caa)
     gene            2328..4976
                     /gene="polA"
                     /locus_tag="ACGI3L_003256"
     CDS             2328..4976
                     /gene="polA"
                     /locus_tag="ACGI3L_003256"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFG9198951.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            4985..5587
                     /gene="coaE"
                     /locus_tag="ACGI3L_003257"
     CDS             4985..5587
                     /gene="coaE"
                     /locus_tag="ACGI3L_003257"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFG9198952.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            5580..6134
                     /locus_tag="ACGI3L_003258"
     CDS             5580..6134
                     /locus_tag="ACGI3L_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HFG9198953.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            6134..7849
                     /locus_tag="ACGI3L_003259"
     CDS             6134..7849
                     /locus_tag="ACGI3L_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9198954.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKVKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            7922..8134
                     /locus_tag="ACGI3L_003260"
     CDS             7922..8134
                     /locus_tag="ACGI3L_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFG9198955.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            8335..8934
                     /locus_tag="ACGI3L_003261"
     CDS             8335..8934
                     /locus_tag="ACGI3L_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198956.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            9162..9533
                     /locus_tag="ACGI3L_003262"
     CDS             9162..9533
                     /locus_tag="ACGI3L_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9198957.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            9665..10939
                     /locus_tag="ACGI3L_003263"
     CDS             9665..10939
                     /locus_tag="ACGI3L_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9198958.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            11050..11994
                     /locus_tag="ACGI3L_003264"
     CDS             11050..11994
                     /locus_tag="ACGI3L_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198959.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
BASE COUNT         4976 a         1198 c         2169 g         3712 t
ORIGIN      
        1 cacttaaatt aatttttata aaaagttcaa taacatttta taatataatg ttattgaact
       61 tttttattgt ataatacaat ttttatattt attgtattga ttgaaaaatg cttataaatt
      121 taaatgctta caattttgtg catgaataga gaggtatatt attttattaa actgtataat
      181 ttgcttggag gtaatatcaa atggaatgga taaataaatt aaatcaagct attacttata
      241 ttgaagaaaa tctcgaaagt ggagtggatt atgcagaagc agcaaaaatt gcatgttgtt
      301 caacctttca ttttcaaaga atgttttcat atattgcaga agtaccatta tctgaatata
      361 ttagacgaag acgtatgact aaggctgcat ttgaacttca gaacagtaac atcaaaattt
      421 tagaactatc tgagaagtat ggttacgatt caccaacatc ttttaataga gcttttcaaa
      481 atatacataa catttctcca tctgcagcta gagcaaaggg tgttgtttta aaagcatatc
      541 ctaagatgac attaagcatt tatgtaaaag gaaatataga aatgcaatat cgtattgtag
      601 aaaagaaagg gtttcgtatt gttggtataa aagaaagtat gaacatgatt gtagaagagt
      661 gctttgagaa agttcctaag ttgtgggcta aatgcataaa aaatggaaca attgataaac
      721 tttcagagtt aataaataat gaaccttgtg gattgcttgg agttagtgtg tgtacaaata
      781 gtaagggttt agattattat attgctgctc caacagataa gcctgtatta gaagatactc
      841 atgaatactt aataccatca ggcacatggg cagtatttga atgtgtttct ccaatgccaa
      901 atgctctggc aatacaggaa ttgcaaaaaa gaattattac tgagtggtta ccaagttctg
      961 ggtatgtgta tgctaattta ccagatattg aactttatcc caatggcgat atcaatgctc
     1021 ctgattatac tacagaagtt tggattccaa ttcagaaacc aagttaaaat taataaataa
     1081 tatggaatta ataaataaca ttaaaattaa taaacaacat gaaattctaa aattacaggc
     1141 tgaaaatagt ctgttatttt tttgtaaata tggaaagtaa gctttacata aatggaatat
     1201 agttgtataa ttatggaaag tagactttcc gtagttgaga tattaaaggg ggatagatgt
     1261 gaaaaataga ttagaagaaa taagaaaaga aagaggcata aaacaagaag aacttgcttc
     1321 tattttgcaa gtatcaagac aaactatagg ttcattagaa aatggtaggt ataatccttc
     1381 tatcatctta gcctttaaga tagctagata ctttgatatg agtattgaag aaatatttat
     1441 ttatgaggag gagtaaaaat gaaaaagaat atgttatatg ttggaattat atattttatt
     1501 tgtggaattt tacttgtttt attggctaca tttactgagt tttcatttga ggcttttatt
     1561 tggggattat ctggagctgc tttaggtcca ggtgtatgta tgattcttca atatatgtat
     1621 tggagtaaac ctgaaagagc agtagattat gaagaaaaga taaaaaatca aaggatagag
     1681 atgaatgatg aaagacgaat tatgttacgt gataaagctg gacgtatcac taatcaaatc
     1741 atgtcctatg ttcttgtaat tcttatattt attgtttcta tattgagtgt attttctgta
     1801 atggtaataa gcaagtgggt tttagttgtt cttggattgc ttattttatt tcaatttatt
     1861 tgtagtgttg ttgtatacaa taaattagat aaaaagttgt aataagttat gatataaaat
     1921 agaaaattat ataaaaataa attagttttt aaattaatgc tagaagataa atttatataa
     1981 ttatataaat tttaaaaaga cacagtaatt tcaaaaaata acttaaaatt taaatcaaaa
     2041 ataaaaaaac tcctaatcta ttgaataaat agctttagga gtttttaatg gtgcccgagg
     2101 ccggactcga accggcacgg agtattagtc cggtggattt tgagtccact gcgtctacca
     2161 attccaccac tcgggcatgt catgtatatt attatagcaa aaaaatatat tgtttgcaac
     2221 atatttaatt ttaatatact attattatta tgggaatatt aaataacagt atattggtat
     2281 ataatatata tgttacaaaa atagataatt tttaggagtg atataatttg gaaaaaaaat
     2341 taattataat agatggaaat tcaataataa atagagcttt ttatgctctt ccagaaatga
     2401 ataataaaga agggctaaag accaatgcaa tatatggatt tacaacaatg ctatttaaaa
     2461 tgatagatat atataaacca acacatataa gtgtagcatt tgacagaaaa gcacctacat
     2521 ttagacattt agaatataaa gagtataagg ctggaagaaa gggaatgcca gatgaactgg
     2581 cagaacaatt acagccatta aaagaccttt tagataaatt tagaataaat agattggaaa
     2641 tagatggcta tgaggcagat gatattatag gtactgtttc taaaaaagca gaagaaaatg
     2701 gatataaggt atacatagta actggagaca aagatgctat tcaacttgct tcagacaata
     2761 caactactct tataacaaaa aaaggagttg gagaagttga agaatacaac tttaattctg
     2821 taattgaaaa atacgagatg actccaacac aatttatcga tttaaagggt cttatgggag
     2881 acaagtctga taatatacct ggagtacctg gaataggtga aaaaacaggt ataaagctta
     2941 taaaagagtt ttctagtata gagaatctaa tagagaatac agataagctt aaaggtagtg
     3001 taaaaaagaa aatagaggaa aacaaagaaa tagctattca aagtaaaaga cttgcaacaa
     3061 ttataagaga tgtgccaata gaagtggatt tagatagtat gatttttggc gattatgata
     3121 aagatgaact tttagataaa tttagatact ttggatttac aagtctctta tcaagattag
     3181 ttgatttggt cgattcagat gacacagaac acgtagaaga aaaaatagaa atattaaaat
     3241 taaaagatat agaaaaattt atagatgaag taaacaaaaa aggacaagtt attttaaaaa
     3301 ctgttagagg acaaggtaat atacttgaaa aaaatataat atatattttt ataagtgtag
     3361 atggagaaaa aatatattat gtagattcaa atgaagtgtc aaagttagat agtatatttt
     3421 caaataatga aattaaaaag tatggatata atttaaaaga tgattatata tctttaaaac
     3481 catataatat aaacttagaa aatatgtatt ttgatataac aatagctgag tacttaatag
     3541 attcaacttc atctacctca tatgattgta gtgcaatagc tatgaagtat ttatcaaaaa
     3601 aggttaaatc aaaagaagaa ttattaggaa agggtgttaa atctaaaaac tatgaggatt
     3661 tagaatttga ggatttagca gagtatatgg gtcaaataat atgcacagtt aaagaaacag
     3721 ttcctatgat ggaaagaagt ctaatggata tgagtatgga tggtcttttt tatcatgtag
     3781 agatgccttt agtagaagtc ttaggtcata tggagtatga aggtataaaa gtagacaaaa
     3841 gtatattgga tgaattgagt gttgaattta aagaaataat agctacatta gaaaaggaaa
     3901 tttatgaatt atcaggagag ccattcaata taaattcacc aaaacaattg ggtgttatat
     3961 tatttgaaaa attagagctt ccaataatta aaaaaactaa aactggatat tcaactaatg
     4021 cagatgtttt agaaaaatta agagataagc atccaataat agataagata actgagtata
     4081 gacaaatagt aaagttaaat tctacttacg ttgaaggact tttaaatata ataaatccag
     4141 aaagtaatag aatacattca tcatttaatc aaactataac gactacagga agaatttcat
     4201 ctacagaacc aaatcttcaa aatataccta taaaaatgga aatgggtaga aaaataagaa
     4261 aagtgtttat tgcagatgat aactgtaagt tggttgatgc cgattactca caagtagagc
     4321 taagagttct tgcacatatg agtcaggatg aaaatatgat agaagcattt aaacatcatg
     4381 aagatattca taccaaaaca gcttcacaag tttttaatgt tcctatggaa gatgttacta
     4441 gtgaattgag aggtgcagct aaagctgtaa actttggtat tatatatggt aaaagtgact
     4501 ttggtctagc tgatgattta aatatacctg ttccaaaggc gaaagaatat atcgaaagtt
     4561 attttgctaa ataccataaa ataaaagagt ttatggacac aacagtagaa aaggctagtg
     4621 aggatggata tgctgtaaca attttaaaca gaagaagata tataccagaa ataaagtcaa
     4681 gcaattttat ggaaagaaat agaggaaaga gatttgcaat gaatgcacca atacaaggaa
     4741 gtgcagcaga tataataaaa attgctatga taaatgttca taaaaaattg gaagagaaca
     4801 atttgaaatc aaaacttata ctacaagttc acgacgagtt gatagttgaa gcaattgatg
     4861 atgaaataga tatagttaag aaaatagtaa aagaagaaat ggaaaatgct gtaaatatgg
     4921 atgttcactt agatgtagat ttaaatgtag gtagttcttg gtatgagaca aagtaggtga
     4981 ttttatgttg atattaggac ttacaggagg aataggctgt ggaaaaagca gcctatcaaa
     5041 tatatttaga aatcttaaca ttcctatagt ggatgctgat attatatcca ggaagatatt
     5101 tgaggataag ttgttattgg aaaaagtatt tgtccatttt gggcaaagta taaaaaatga
     5161 tgatggaact ctaaatagaa aagctcttgg gaaaatagtt tttagtgatg aagaaaaact
     5221 taaggaatta aataacttga ctcatccacg aataagagaa aaaataataa gtgaaataga
     5281 aaaattgaga aaaaaaggcg aaaatatagt agtgttagat gcggcaatat tggtagaaag
     5341 tggtttttta gatatggttg acaagctatt agtagttact tgtaaacaag aagtacaaat
     5401 tagtagaata caaaagagag ataattgcag tgagcaggaa gcacttagta ggataaattc
     5461 acagatgagt caggaagaaa aatccaaata tggtgattat ataatagata attcgggaac
     5521 aataactgaa ttagaaagta aagcacataa atttattgag tacatgaagg agaattggcg
     5581 tgaatagtaa gaaagtattg attctatcta tttttataat cttatttggg gcactattaa
     5641 tggaaagcaa agtaatacat aaatttttat atcctaaaaa atattcagag tatgtagaaa
     5701 agtattcgaa agaatttaat ttagatgaaa atatagttta cagtgttatt aaagccgaaa
     5761 gtaagtttaa tagttctgct gtttcaaaaa aggaagcaaa aggattaatg caaatattag
     5821 acataactag agattgggga gcagaggaac taaatttaaa aaatgtggat attttcgacc
     5881 cagagactaa tataagactt ggctgttggt atttaagtaa gttatacaaa gaatttggta
     5941 aattagattt agtgatagct gcatataatg gtggttcagg taatgtgaaa aaatggttag
     6001 aaaataatga atatagtaaa gatggcgaaa atctacatga tatacctttt aagcaaactt
     6061 caaaatatgt agaaaaagta aaaaataatt acgaacatta taataagata tatggcaaga
     6121 aaggaaaaaa ctaatgaaga gaataaaagt cttaacagtc gttttagcta taactcttat
     6181 ggtagctggt tgtagtaata ctaaaacaaa acaaagtagt agtgattcaa gtttacaaag
     6241 tcaaagttct atagatgcta agtatataaa cttaacaatg gtaactccaa aaactataaa
     6301 tcctataact aatactgata agtctgttgg ttatataatg aatttagttt atgatagttt
     6361 atttactata gatgagaact acaatgtaat tcctcaatta gttaaggagt ataatatagc
     6421 tcaggatgga atgagtatag atataaagct aaaagatgca aagtggcatg atggaaaaaa
     6481 tgttacttca aatgatgtaa actatactat tggtttaatt caaaaaagtg cagatagtcc
     6541 atataatgaa tttactaaaa atatagcttc tgtgaatatt aaatcagata aagattttac
     6601 aataaaattt aaagctagat atgctttttc aattgatagt ttaatttttc caattgtatc
     6661 tcaaaatcat ttagattcaa aagatgtaaa tgacaagaat aataatatga taggaaatgg
     6721 gaaatataaa atagaatcat atacagaaag agaaggaatg gttttatctg taaacaaaga
     6781 ttactatgaa gaagttccaa aaaccatgaa gaacataaaa gtaggtatgg tgcctaatga
     6841 agatgcaagg acatctatgg ttatggctct tgatagtgat ataaccaatg ttacattaaa
     6901 tgatttaagt aagtttcaag aaaaagagtt taatataaca aaatatcaag gaagagatta
     6961 tgagtgtgta ttatttaatt ataataatcc ttttttcaaa gatgttaatt ttagaaaagc
     7021 aattgcacac tctatagata aagatagaat tattagtgaa ggttatatgg atgatgctac
     7081 tccagttaat tttccactta attcaaaatc aaaatactat aatagtgaaa tgaaggattt
     7141 agagtttaat aaagataagg cgatagagtg tcttgctaag gtagaatatg caaatgtaaa
     7201 ctcagtaaat caaaatgaca ataaagtaaa aaatcagaaa aaatcagcta aaaagaactc
     7261 aaagaagctt acgccagaag aagaagcaaa agttaaaaaa gcagaagaag atagaatcaa
     7321 aaaagaagct gaagagaaaa aaaatagaga aaaagaggaa gtaaagaaaa gtctttctga
     7381 aatgaactta aagataatag taaacagaga taatagtgag agaataaaaa ctgcaaacat
     7441 aataaatgaa aacttaaaag ctataggaat aaatagtaca gtaaatcagc tctcagataa
     7501 ggatatggaa aatgctctta attctaaaaa ttatgattta gcattagttg gatggaaact
     7561 atcaattata ccagatgcaa gtagtattat agcgagtagt ggatatactg atgataagtt
     7621 aaatggatat atgtctgcac ttacaagttc tacgtctgaa attgaaacaa aaaaagcata
     7681 caaagatgta cagacatata taaaagataa tgcaacattt ataagtttag ctgtgagaaa
     7741 caactatatt gtaagtaata gtagattaaa aggtaaaatt actccaaatg attttgatgt
     7801 atatgaggga atatctaatt tagatataaa atcgaatgaa tcaaattaaa tgattaattt
     7861 ctatttaaaa agtataaact atatgataga atacccttat agggtataag gaggtaatta
     7921 aatgaagaag aaactattag tagaaggtat gagttgtggt cattgtgtaa accatcttaa
     7981 aactgcatta acagaagata tagatggtat tgaagtttta gatgtagatt tagaaaataa
     8041 gtgtgcatct gtagatatga aagatgatgt atctattgaa aaattaaaag aagtgatagc
     8101 agaattagga tttgaactaa agggaattga atagaaattg ataaactaaa aaaagacctc
     8161 tattggggga gtaatagagg tctaaaaatg ggggagattg agtatgtttg attttacatt
     8221 actattatct ccccttttaa attaatatat acataaaaag taaaaaaatt ttgtaatgac
     8281 tcacatttct tgagcttttt gaatatacta taaatagcta agggagggag tatcatggaa
     8341 tctaggggat ataaagagga tttaaaaaaa atgatacttg atatggccca caaagaactt
     8401 gagagttatg tatcacaaaa aggagcaaaa aaatactttg aaggtaactt ggataagatt
     8461 attaataata atataaaaaa attcaatcaa agtattggtc ttaatagagt atatttaaaa
     8521 atgttaaaaa agtgtgcata tcaagaaagt gtaacttcaa tatcaagaac tataaagaaa
     8581 gaagcattat ttaaatcaaa aaaagagcta tttgcttttt cagagtactt aaaacttgat
     8641 attaacaagc gactttcata taatcaaatt ttaagaaaaa tatcaagata tatatactac
     8701 aatagaagtt catatgctca aaaatacgtt gttttcaaaa gaggagatga agaatatctt
     8761 ttagaaccag agaaaataaa agatgaatta atatcaagct ataggtcaaa gactagagaa
     8821 gatatgaggt caatagcaaa acttttggat atagaagtag aagatgatta taatgctgaa
     8881 gatattagaa aaaaagtaat aaattatatt attaaagaaa aacttaaaag ttagagtttt
     8941 aaagaataag ttctgccaat ttgcatgatt aagtataact tgggtataaa ttttttatgc
     9001 atttgaaaga gcttattctt tttttgacat attcttttaa ataatttacc atgatttggt
     9061 aattggtcat catcattcaa atttttaact taatatgatt taaataaatt tataataatg
     9121 atataatata aaaaaaataa aaattggaga gtgatttcaa aatgaagttt aatttttgtc
     9181 ataacaattt caatgttact aatttagaaa aaagtttaga tttttataaa aaagctttag
     9241 ggcttaaaga ggtaaagcgc aaggaagcag aagatggaag ttttatatta gtttatttag
     9301 gagatggcat tactagtcat acattagaat taacttggct tagagattgg gatagaccat
     9361 ataatttagg agacaatgaa tttcatctgg ctttagaagt tgaggagttt gatgaggcaa
     9421 aaaaacttca taaagattta gattgcatat gttttgaaaa tgaaagtatg ggaatttatt
     9481 ttatagcgga cccagataat tattggattg aaatacttcc taaaaatcac taattttaag
     9541 gatatgttta taatttcttt acaattaata agaaaataag ttatcattaa attgtaggga
     9601 ctaaaaatgg ataataatgt tatgaattta tgactataaa aatttgttgg ggggagtgat
     9661 agtagtgaaa aaagctatag cagctttagg aattggggca gtagcagtat ctgttagctc
     9721 cataaatgca agtgctcttg aaaagggaac agtaacagca agtgccttga atataagaag
     9781 tggaccaagt tctgattgcg ataaggtagc aaaattatac aagggaaaaa ctgtagagat
     9841 tttagaaaag tctaatggat ggtataaagt aagggtatcg agttctgttg ttggatgggg
     9901 aagtgcaaaa tacatatcaa caagtggttc gtctgaaggt acatcaagtc aaaataatcc
     9961 aacttcaagt gggacaacta ttagtggaaa tggtaaagta aatgtgagtt ctagactgaa
    10021 tgtaagaagt ggtgcaggta ctaactattc attagttggt aaagcaaata atggagatgt
    10081 agtaaagtta ctagaacaaa gcaatggatg gtataaaata aaactatcaa atggagttac
    10141 tggatgggct agtagccaat atatttctaa aacatcagaa gatgttggaa cgaacaattc
    10201 tagtaattca aatagtacta ataattctga taaaaaacca tctagcgaag aatcaattga
    10261 aggcaagaat ggtaaggtaa catctgctgt gagtttaaat gtaagaagtg gtcctgggac
    10321 aagctattct ataataggaa aattaaatgg tggagatgtt gttgaattaa aagctaaaag
    10381 taatggttgg tataaggtaa agttatcgag tggaacaatt ggatgggtga gtgccagtta
    10441 tatttctgag actaatgagg atacaaaaga aaaaccaaat tcatcatcta accaaaattc
    10501 tcaatctaat agtaactcaa agccatcatt tactggaaat tcagataaat ctacagcaaa
    10561 aggttcaaca atcgtagatt ttgcatatac tcttattgga ataccatatc aatggggagc
    10621 ttcaggacct gataaatttg actgttctgg atttacacag tatgttttta aacattctgt
    10681 aggcgtttct attcctagag tttctagaga acaggctaat tttggaagtg caatttctat
    10741 gggaaattat gcaccaggag atttagttta ttttgacact gatggtgatg gaacaactaa
    10801 tcatgtaggt atatacgtag gaaatagtaa atttatccat tgtagtggta ctcagactaa
    10861 tcctaataag gttaaagtgg ataatttaac tagttcatat tggtctaaag tattacttgg
    10921 tgcaagaaga tttgtttagt aagtacaatt tcttattaaa aaattagaag aaataattat
    10981 ttatattcat aaattgtgac tcttaaaaat atactttatt aataatataa ttttgggagg
    11041 gacaaactaa tgaatagaag aaaaacgata tacagaggat ttaataataa tagacataag
    11101 attgatttac gtaaatatgt tataacgatt gcttgcttgt gtctaattgg ctattattct
    11161 tatacaaaaa taaaagatag caagatattg gagtatgtat cggctaaaat accatttcta
    11221 aataattcat cagatataac ttataaagat atatctgatg aattaaattc aataaaaaaa
    11281 gggaaaaaat ctaaatcaca aaccaattca gatgataaac aagaaactaa tccagaaaaa
    11341 gcggtaaata acactaaaga gccagaagaa gtcaaattag ctactataga aggctgggat
    11401 atgtatacta ttcaagttgc tgcaatagat aataatgatg atttgaaaaa aatacagaca
    11461 tcattagtta ataatgacat acctttttca gttatggaga aggatggagt aaaaaaaata
    11521 cagacctatt cctcttttga tgaaaatgat gttagaaagc agataagcag tgtaagaaag
    11581 gtgtttccag atgcattttt atcacactta gatgcaccta tgttgtcttt agagtataca
    11641 agtaactacg cttatataga gagtatatct aaagaattaa ataaattaat aacaaacttt
    11701 aaagaagaat caagtttttg gtcgaatgct gaaaataatg tagatatgga aaaatataat
    11761 actattttga caaatagaaa ggcaatatca caaaatatat caaaagaagc tgaaaagatt
    11821 gattattctg aaatgcgttt atttaaagat aatttaatag agtatgtaaa gaatgtgaat
    11881 gaaaaaattg atacagcttc aaaagcagca aatgaagaaa aatatagtgt aagtaaaagt
    11941 ctgcttttat catccatgca ggagtactct atgtttataa attctataaa ataaaataca
    12001 gaaaatttgg actttagaaa gctatatgaa aaggattgtt taattaagca atcct
//
LOCUS       DAYAKB010000099        11929 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.099, whole genome shotgun sequence.
ACCESSION   DAYAKB010000099 DAYAKB010000000
VERSION     DAYAKB010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.099"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..2192)
                     /locus_tag="ACGI3L_003265"
     CDS             complement(<1..2192)
                     /locus_tag="ACGI3L_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9198960.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSGGSSSNQTSVNNEAAKITSVPTPAKDATRLTMPSVSSGYTIAIKTSSNE
                     SVIKKDGTIIPPNTATTVKLVFTVTHTSSGKTADTKELSVTVPAKSTDEELQAALDNE
                     VAKITSVPAPAKDATKLTMPSVSSGYTIAIKTSSNKSVIKEDGTIIPPNTEETVTLVF
                     TVTQESSGKTADTGEIDVVVPAKSTDGEIQAEVQAEADKITSVTQPTQ"
     gene            complement(2976..3164)
                     /locus_tag="ACGI3L_003266"
     CDS             complement(2976..3164)
                     /locus_tag="ACGI3L_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198961.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(3190..4329)
                     /locus_tag="ACGI3L_003267"
     CDS             complement(3190..4329)
                     /locus_tag="ACGI3L_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9198962.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDELYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFISKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(4866..5705)
                     /locus_tag="ACGI3L_003268"
     CDS             complement(4866..5705)
                     /locus_tag="ACGI3L_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9198963.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5729..6487)
                     /locus_tag="ACGI3L_003269"
     CDS             complement(5729..6487)
                     /locus_tag="ACGI3L_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9198964.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6534..7007)
                     /locus_tag="ACGI3L_003270"
     CDS             complement(6534..7007)
                     /locus_tag="ACGI3L_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFG9198965.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(7036..7452)
                     /locus_tag="ACGI3L_003271"
     CDS             complement(7036..7452)
                     /locus_tag="ACGI3L_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9198966.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIVINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7499..8551)
                     /locus_tag="ACGI3L_003272"
     CDS             complement(7499..8551)
                     /locus_tag="ACGI3L_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9198967.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            8947..9627
                     /locus_tag="ACGI3L_003273"
     CDS             8947..9627
                     /locus_tag="ACGI3L_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFG9198968.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9760..10080)
                     /gene="sugE"
                     /locus_tag="ACGI3L_003274"
     CDS             complement(9760..10080)
                     /gene="sugE"
                     /locus_tag="ACGI3L_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HFG9198969.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     regulatory      complement(10150..10256)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            10462..11289
                     /locus_tag="ACGI3L_003275"
     CDS             10462..11289
                     /locus_tag="ACGI3L_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HFG9198970.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
BASE COUNT         3868 a         2056 c         1352 g         4653 t
ORIGIN      
        1 tcttgtgttg gctgagttac acttgttatt ttatccgcct cagcttgtac ttctgcttgt
       61 atttccccat ctgttgattt ggctggtact actacatcta tttctcctgt atctgctgtt
      121 ttaccacttg attcttgtgt tactgtaaat accaatgtta ctgtttcctc tgtatttgga
      181 ggtattattg ttccatcttc ctttataaca ctcttattgc ttgatgtttt tattgctata
      241 gtatatccac ttgatactga tggcatagtt aatttagttg catcttttgc tggtgcagga
      301 acgcttgtta tttttgccac ttcattgtct aatgctgctt gtaattcttc atctgttgat
      361 ttagctggta ctgttacaga taattctttt gtatctgctg ttttaccact tgatgtatgt
      421 gttaccgtaa atactaattt tactgttgtt gctgtatttg gaggtattat tgttccatct
      481 ttttttataa cactctcatt acttgatgtt tttattgcta tagtatatcc acttgatact
      541 gatggcatag ttaatctagt tgcatctttt gctggtgtag gcacgcttgt tatttttgct
      601 gcttcattat ttactgatgt ttgattagaa gaacttcctc ctgaagatga gcctcctcca
      661 tgtgaagaac ctccacttga tgaacttcct cctgaagagt tagaacttgg actatttcca
      721 cttattgttg gagaattatc tcccttaaca ctacttattg tacctttatt atctatagta
      781 gtccctttag aattatttgt aactgtagtt atcttaccac cattagtcac ttttacttga
      841 cttgctccag atgctactgt taaactacca atctcacctt tagaattatt ttctatcttg
      901 gctccatttt tatcattaac ctttaagtta gttatttttc cataattaac aaaagttcca
      961 tcttttacat catctataac tacatcatcc acttttgcat agttatttac atcaccatta
     1021 ggcatgttga tagtcacagt ctttgtatat gtaccattta agtttactgt tactgcttta
     1081 tcagtttgta ttgtaaatgc ttctttaacc tcactagttg gcttaaagtt tataacatca
     1141 ttagcagtag ctttatctat agctgatttt aattcagaaa ttgttttagc ttcaactgtt
     1201 tttacttctt gtaatgactt catttcatta aatgctgtct cattaccatt cccaccaact
     1261 ttagttatct tatcaaaact cttagagtta actagagatt tttgtgaagc tgataagttc
     1321 tttccaacta aaactactgg tgattgattt ttagcaccta atacacctac tgctagtgca
     1381 tctataagtt ggtcttgttt attcatacca tctttagtta cataagcatt ttttaaatct
     1441 gtctttttat aaaattcttt tattactttt gcatttgtat catttctatc tgttccacct
     1501 agtcttgtac tatttggtag tttattttta acagcttcag aaattgaact ctctccacct
     1561 actacataag attgagttat tccagcatcc tttataaatt tgtctgcaac tgctgttcca
     1621 tttttagaat cagcaagtat tactggcata ttgttttgtg cagctggtgc tcctacactt
     1681 acagcatctg caagtccttt ttcaccatta actacagcta ttttcttaac atcacttata
     1741 gcatctaatt tctttgctaa ttctaaggat gtttgatatc tctcagctcc agagattctc
     1801 tcaaaagata tttttaaatc ttttatttct ttttctatat ttgtacttaa tacagaagtt
     1861 ccacctatta agtatacttt tttagctttt aatctttgta tttctgcttt cgtcttatca
     1921 tttaatttat ctttacttgt taaaagtatt ggagcatttt ttgcttttgc aaatggtgtt
     1981 gcagatagag catctgctat agatgagtcg tttacgatta ctacctcatc agcatttttc
     2041 catccatctt gacttatttt aacagcagtt tcatatcttt cttgccctgt taaatttgtt
     2101 gccacagttt gtgcactagc tatgcctgct gttgaacttc cagctatcat tgtaactgta
     2161 agcattgcag caatcttctt tggtattttc attttatttt cttccccctt gtccatttga
     2221 tattacttaa ttttttaact ttgttcccgt tctaattcta aaggatactt aatatctaat
     2281 tttaaagagg tttctaacta taatgatttc ataattaatt tgtaattatt ttgttacatt
     2341 gcagtcatta tgtaaggaat aaagaaattt tcttattgat tgaaaaattt gtaaatttat
     2401 attttaaggt aagtttgatt tttatgttaa tgaattgtta taaaaaatag ggttttgtat
     2461 aaaaaaagta gcctttagaa ttaaaagtgc tactcttttt acaaataaat tttattattt
     2521 atacttgtaa ttatatatta aataaccaat tttatccata tgaaaaacaa ataattgcga
     2581 tattttttta attattcttt atatttacat tttaattcaa attacttttg taaagattat
     2641 atctgttgca tatactactt taagtgctaa tatctctcca cctcaattag aatcctcgtt
     2701 atctcaatag acgttttcta ctgtcaaagt taccaacatt tgaaacttat taaattttta
     2761 tataaaaaag acctagaata taaattccaa gtcatttttt attaaattta ttttttacaa
     2821 tataatattg tcatgattaa agaacacaaa tcatacacaa attggtcata aatcttacat
     2881 aaatcatcta caaaaaatac attatttata ttaaatctat ataactaaat taagagcata
     2941 ttgtacaata tgctcttaga aaagatattt cttgtttata gtttatagta tttctctatg
     3001 atttttattt ttatcatttc aaaaataaaa attaagatta cagttattat catattttgt
     3061 gtactatttt ctataatatt ataatgaaac aatgaaaaaa caataattaa tgaaattacg
     3121 tttatagccc cagaaatcaa aaatgccttt ttcttattat tcatatattc cctctccaga
     3181 ttatctaaat tagtctatat caagcatttt taagtactta tcattaactt tatatatatt
     3241 tttttcttta gacaaaatct ctatctcttc aagattatta aacacttcca tcaactggtc
     3301 aactaattca atttccttta ttccagcctt taagtatcta cttttattct tttttatata
     3361 attttctaat gtcatagaat agttatcttt attgcaaata tattttaata tatgttcttc
     3421 tgttgctgat agagttatgt cattttcaaa caattcttct tttaatatac tttctaaaga
     3481 ttttctatca tgcatattac gcatctcatt aatagattgt attatagact tgagcataaa
     3541 ttctataaat acagttaaat tatttccttt gttttctaca tcaagtatag ccttataata
     3601 cttagttctg tttttagata tcatatatga tattgaaaaa tccttgaaag tatcatatcc
     3661 tttatcaatc aaatatagat atgataaggc tcttgatgtt cttccattac catcactaaa
     3721 aggatgaaca tatacaaagt aaaaatgaat tatagcactt ttaattaaat tacttacttt
     3781 gctattttcc ataaaatcta ttaatttact aataaagtca tatatcttca aaggttcaag
     3841 ccctgtatgt ataatctcac cttttgaatc acatacatat actttttcag ttctatactc
     3901 atattcttct gaatccaagc agttttcgcc caatatatga tgcaaatcat atataaattt
     3961 gtgactatac aattcatcta agttatctaa tccatattct aaggctctat gattattgta
     4021 aatcatatat tcacttttat tacttggttt catctttcct ctaattatag attttgcaat
     4081 ctttctagtt gaaaaagcac cttctattac actagaataa taagactcta gtgccaaatc
     4141 atttttatct tctattgttt taaatatctt acttgatgtt aatttatcta tttcatttat
     4201 taaatttaat atattttcag tttcatgata gtatagttct ttattatcaa aactatttat
     4261 agaaagtacg attttatttc cagtaaagta tttgtttttg tattcttcta ttgtcagttt
     4321 aatcaccacc ttagattatc tttatctatt aatattaaca aaaagtatta atttttacac
     4381 tatttttgat tatttgtttt ataattatca aactcaattt agcgttaaag cataataaat
     4441 tttaataaat aatgcaaaaa tttaagaata agcatttaaa atatatgtta caggaagttt
     4501 acaactatta tttataatac attagttata tattataata tctcgacaat gtcttaacaa
     4561 tatctcgatt atatatttta atatgtaact aatatgttat aatattttaa ttaaattaaa
     4621 taaatttata tttttttgaa attacttaat attttatata aaaatgaaaa agcacctcat
     4681 tctgattaaa aatctttctg agatactttt taaaatatta aatactacat atagcttaca
     4741 taagtttaaa atttaatcta ttataaaatt accctaattg ccaaactttt taatataaat
     4801 tttccaacat cctacaaata taatcaatag atatagaatc ctaacttaca ccaatatata
     4861 tttatttaaa atagtcctaa aatacctgta atagctccca ctactatcag tataaacatt
     4921 atttttattg gagaaagacc tttttttaat gcaaagagta ctaataaagt aagtaccaaa
     4981 ggaattaatc ctggaaatat cttatcaagt aaatccgttt gaagactaaa tttaaaatca
     5041 ccactagtat aacttattgg tgtagataaa ttgataaacc tacctacaag cccccccatg
     5101 actaaggtac ctagtataga agccccttct ataaccttat ttactattcc accttgaagt
     5161 atactttcaa cagctttttt cccatactta tatccatttg tccacattcc aaaagaaatt
     5221 gaagtcatta ttatatattg agctattaca aataatatag gtcctgcaat tgatgctcct
     5281 ccctcagtta aaccaataca aacagctaac actataggag ttataactcc ttgagttaaa
     5341 gtatctccaa ttcccgctag tggacccatc aagcctgttt tgatagcatt cataccatct
     5401 ccacttattt catctgctcc attagctttt tcttcttcca tagctattgt tattccatgt
     5461 ataacacatc cacatatagg ttctgtgtta aaaaatgcta gatgagtctc cacttcttgt
     5521 tttaactctt ccttatctgg atataatttt ttaagtactg gcaacattga atgtgaaaaa
     5581 gctgttgatt gcaatctttc ataattgtaa ttagattgtg caaagaaaaa ccatcttaac
     5641 catgatttta ttacatcttt cttgcttaac gttttcttag atacttcatt ttttatatct
     5701 gacataatat tttccccctc acatgtattt aagatgtagc actatctttt ccgtacttaa
     5761 ttgaagtaat tgtaagagca agtattactc caataacaga tattactatt atatctactt
     5821 taaaataaac agccattagt attcctaata tgaaaaaggg catagtaaac ttatttccaa
     5881 tcaattttaa attcatagca atcccaagtg ctggcaacat agccccaatt acattaaata
     5941 catgtaacac attatcattc attacttcca acataccatc tatcgcattt ggaccaaaat
     6001 aaacaactaa taatgctggt ataaaactca ttgcaaataa cagtatctgt ggtggtacta
     6061 tatttataaa tgctactcta tcaacattcc ctttttgaac ctctctatca gcccaatgtg
     6121 caaaaaaaga atttactgtc atctttccaa tccaaagtac agttgcaaca gttcccaatg
     6181 gtacagctat tgccattgca gtacttacat ctagcttaga tgctatagct aaagcagtac
     6241 ctacatatcc tgcaaaagct gggtccccca tctgagctcc ccctgctgat ataaaaccta
     6301 gatatatcat atttatacct gctcctataa ttgctccttg aacagggtct cctaatataa
     6361 ttcccgttac aaatccagcc aatagaggtc tattccatgt aaaaaatcca acataagtca
     6421 accacggact ccaagaaaga taataaaaaa ttgctattaa tactgcttga attagtgaaa
     6481 tgtgcatatt cttcctccct attttctttt aaagatttac aagatagtct tctttacaat
     6541 aatgttccta catcaatttt ctttgcatct ggtactattt gtataaagca tttaacatct
     6601 tttgatatta gctctctaaa tatttctttt tcttcatctg acacagatat atttttataa
     6661 aaactttttc taccaagccc tgctcccata cctccaacat tcaattcctt taaatctacc
     6721 ccactattta ctaaacctaa gacagtttta gggtatttga ccaatactat taaattttca
     6781 tctccattat gtgattttaa gacttcagca cctgattcta catcatgtac ttcaacctta
     6841 acagttgatg gagctgccat ttgtaaaact tgaactataa atgggtcctt tactactaaa
     6901 tcatccacga ttactatcct ttttgctgat gtaatcttac accaagcagt aataacttgc
     6961 ccatgtatta atctatcatc aattcttgtt aatgctatat tactcataat tattcctcca
     7021 gatttttaat ttattttaca actttaaaac agttttaaca tctttgattc ctgatatccc
     7081 aacttcctca cataaattct tcaagtcttt taacttcata gtatctctgt ttaaaaataa
     7141 ctctaaaagc ataggtaaat ttacacctgt caaacattct aactcacata ccttagcaaa
     7201 tttatttatt acaatagcag atgtattaaa tggagttccg ccataaaaat caagcaatac
     7261 taaaacccct tcatccttat atttctcaat tccatcttct aactttctac taaactcatc
     7321 tatgctgtca ccatggttta atcctaaagt ttctacattt tcctgtttgc ctactattaa
     7381 ttcagcactt tctaacattg ctttagccat atttccatgt gtggctataa ttattcctgc
     7441 catatgaatc atacctttct taaccttttt tatatggatt attatttagt actctaatct
     7501 aattatctat attaatcatt atcttaccaa agaaaatatc ccttttgtat actttttcaa
     7561 aataagctgg tacttcttct aaatttattc tatgtgttac taatttttca acattcatat
     7621 cacccttttg catatgatac aatccagcac tccattcttt tcctgggaat ggaaaggagt
     7681 ttccaaacca agttcccttt acagttaatt cacttcttac tatcttttca aattgctctc
     7741 tagtcaaagc tacatcccca tatggtacac ctgcatacaa tactgtacct ccctttttag
     7801 ctagcaacag tacttgacca catgtcagtg gagtaccagc cgattcaata acaatatctg
     7861 caccatctcc atcagttaac ctttttattt cttctacaat attcttttct tttgcattta
     7921 tacaaatatc tgcccctaac tcttttgcca agtctaactt ctcatcaaat acatccacag
     7981 ctattatttt tgtagaacca aatatttttg cccattgtat tgaaaataat cctattggac
     8041 ctgtaccaag tactacaaca gtatctccaa ctttagcttc tgacctaaaa agaccatgtc
     8101 ctgctataca tactggttct agcgcagcgg cagtctcata acttatctca tctggtattt
     8161 ttattaaatt tctctctttc acctttgtat actctgcaaa acaacctcca agttctttat
     8221 ttcctattat tgctacatta ttacatcttg aatacaagcc ttttttacat tcatcacatt
     8281 caaaacatgg catagctgga caaacagcaa ctctatctcc tattttaaaa ctccttactt
     8341 ctttaccaac ctgtgccact tctccagaaa attcatgccc taaaatttct ccaaccatat
     8401 gtggacctgt ctttgaatat tttgatatat cagaaccaca tattccagct acttttactt
     8461 taattattac atcatctttt tctaatattt ttggtacatc cacatcctcc actcttgtgt
     8521 ctcttatacc atagaatcta actgacttca ctattaacca cccctacttt ttatttgaga
     8581 atatatccct attgtttata tgttaaatat ctaaagcaac tttcatgcca atatatgtaa
     8641 gcattgtatt catgcatttt ataaaattat cattaaatgt gtgtcaaagt gtgtcaaaag
     8701 tttcttatat taaaacttat gtgtgtcaat ataaacgaca ctaacatttt atattagttc
     8761 tcttattata agttttataa aatgtacttt ttttgttatt tttataaaat tgttcggaaa
     8821 tttcccttct atttgtgata taatattaaa tataaggtat caatataaat tttcatgcga
     8881 atatcagaac ttttttgaca ctaatgcctt attcaatata ataatttaac tttttggagg
     8941 ttgtttatga aaaaagtgta tcaaggaaag actaaagatg tttttgaatt agataatgga
     9001 aattacttac ttaaatttaa agacgatgta actggtaaag atggagtatt tgacccaggc
     9061 gaaaatagtg taggtctaag tatagatgga attggtagag ctaatttaga gacatctgtt
     9121 aagttctttg aaattctaaa caatgctgga attaaaactc attatgtaag tgctaattta
     9181 gaagaagcaa ctatggaagt tctaccagca aaagtttttg gtaatggatt agaagttatt
     9241 tgtcgttata gagctgtagg tagtttctta cgtcgttatg gttcatgtgt tgaagaaggt
     9301 gctaaactag attgttacgt agaagcaact ttaaaagatg atgaccgttg tgaccctctt
     9361 ataacatctg aaggtttaga agctttaaac attatgactc aagctcaatt tgattcaatg
     9421 aaaagcatga ctcaaaaaat ttctaacata gttcgtgata ctatagctga aaaaggtctt
     9481 gagctttatg atattaaatt tgaatttgga ttctacaatg atgaagtaat cttaatagat
     9541 gaaatagcat ctggaaatat gcgtgtttat aaagatggtg taatagttga ccctatggat
     9601 ttaactgctc ttttattaga taaatagtat atacatataa tttacaaata taataaactt
     9661 ataaataaga taagctatga agtaaagact ttttaaatgt tgattatttt taaacatttt
     9721 ctcgccttta atttcatagc ttatttaaat taatatactc taattagtag ataatagctt
     9781 taaccctaca attcccacca caataaaacc tatacatgca attcttgata tactaatagg
     9841 ctcatttaaa atagccatgc ctacaatagc tgtaccgacg gtaccaattc cagtccatat
     9901 tgcatatgaa gttccaagtg gaagatgttt tagtgctaat gacaaaaaat aaaaacttac
     9961 aatcattcca acaacagtaa gtatacttgg agttaattta gaaaatccat gtgaattttt
    10021 tagttgaaaa gcccaaaaca cttcaaacaa acctgcaaca aacaaaaata accatttcat
    10081 aaattcatcc ctcttttcaa atatgtctct tatttttcca ataaaataac ctgagaaata
    10141 ttataaaata tctcccaggt ttttgtcctt ccgtgttcac aacaaaaact atgttgtggg
    10201 ttttatctcg gaccagacca atcattaata attgcggaac cctataaaac tctattaatt
    10261 attctatttt atctataata atactatcaa catatataaa aaaagtcaat atatgggttc
    10321 catatataat aaaaataact tttatatacc ttttaatatt cttattcact tctctccata
    10381 cccatttggg tcaatctaag aatatctaat ttttatttaa tatgttataa taacataaaa
    10441 atattgaaag gagtaatttc tatgaatttc tataaaattg cagtatgtca gatgattact
    10501 acagaaaata aaattgaaaa tatcaatcat gctgtagata tggtaacaga agctgccatc
    10561 aatggagcta aaattgtagt tttgccagaa atgtttaact gcccatatga aaataaatat
    10621 tttcctaaat ttgctgaaga atatccaggt gaaacaacaa cgatattaag taaattagct
    10681 gagaaacatg gaatttatct agtttctggt agtattcctg agttagaaga tggaaaaatc
    10741 tataatactt gctatgtatt tgataaaaat ggagctctaa ttggaaaaca tcgtaaaatg
    10801 cacttatttg acattgaagt tacaggaaaa gttagtttta aagaatcaga tactcttaca
    10861 gctggaaatg atgtcactgt aatagatacc gaatatggaa aagttggtat agctatttgc
    10921 tatgatattc gtttccctga gttatcacgt ttaatggctc ttaaaggtgc tgaaatcgtt
    10981 atcttacctg ctgcatttaa tatgactact ggtcccgccc attgggagtt atctataaga
    11041 atgcgtgctt tagataatca gatattctat gttggtgctg cacctgctag aaatatgaat
    11101 gcttcttata tagcttttgg aaattcaaga atttcagacc cttggggaag aataattgct
    11161 caagctgatg aaaaagaatg tattatttat gctgacattg atagagattt aattcctgac
    11221 ataagacaac agttaccact tcttaagcac agaagaactg atttatatga acttaatact
    11281 ttgaaataaa acagaacata accccataaa tcataaatta agtgttaaaa aaatttatgg
    11341 ggttctcatt aatttgattt aaaattaatt tcataaaaat aatgctaata ttaatttaat
    11401 taaataatac taataattac taatgattat gctaattatc agcatttact aatttaatca
    11461 ctattagtta tttcttttat taaatatctt tactttttta cttattatgt cttctagctt
    11521 tacatttgga ttatggtatt tctttctatt tttagtcaca tctttctatt gaattacttg
    11581 cttaaaacac caatgcacac atgccagata atgttcacaa ttatttagaa atcttgctct
    11641 accttcttca atgttgatat tatctctcct agttgatatt atctttccta aaatttcttt
    11701 taattaaaaa acaacattag ttgatatatc aagtatattt taagcaactg aaaaaaacaa
    11761 taataattga tatatcaact aattaatgta gattaattca tttttataat ttatatactt
    11821 tttaattaat ctaccttatt taattaaaat ccttcctttc tatttatcca ttttcaactt
    11881 aaattataag atttcatcag ctatattttt gcataccaat aattattaa
//
LOCUS       DAYAKB010000100        11928 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.100, whole genome shotgun sequence.
ACCESSION   DAYAKB010000100 DAYAKB010000000
VERSION     DAYAKB010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11928
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.100"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..591)
                     /locus_tag="ACGI3L_003276"
     CDS             complement(<1..591)
                     /locus_tag="ACGI3L_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9198971.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
     gene            complement(921..2135)
                     /gene="dpaL"
                     /locus_tag="ACGI3L_003277"
     CDS             complement(921..2135)
                     /gene="dpaL"
                     /locus_tag="ACGI3L_003277"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HFG9198972.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(3010..3297)
                     /locus_tag="ACGI3L_003278"
     CDS             complement(3010..3297)
                     /locus_tag="ACGI3L_003278"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198973.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSM"
     gene            complement(3374..5179)
                     /locus_tag="ACGI3L_003279"
     CDS             complement(3374..5179)
                     /locus_tag="ACGI3L_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9198974.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(5575..5952)
                     /locus_tag="ACGI3L_003280"
     CDS             complement(5575..5952)
                     /locus_tag="ACGI3L_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFG9198975.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6857..7342
                     /locus_tag="ACGI3L_003281"
     CDS             6857..7342
                     /locus_tag="ACGI3L_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198976.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(7542..8081)
                     /locus_tag="ACGI3L_003282"
     CDS             complement(7542..8081)
                     /locus_tag="ACGI3L_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9198977.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(8074..8487)
                     /locus_tag="ACGI3L_003283"
     CDS             complement(8074..8487)
                     /locus_tag="ACGI3L_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9198978.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(8523..9644)
                     /locus_tag="ACGI3L_003284"
     CDS             complement(8523..9644)
                     /locus_tag="ACGI3L_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFG9198979.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            10232..11884
                     /locus_tag="ACGI3L_003285"
     CDS             10232..11884
                     /locus_tag="ACGI3L_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HFG9198980.1"
                     /translation="MNKKNLAILISGIMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
BASE COUNT         3977 a         2003 c         1373 g         4575 t
ORIGIN      
        1 acctttttct ggattagcag agtgagctgg tttaccaaaa gtttctacta ctatttctcc
       61 tctacctctt tgacctatct ttaggtttaa ttctgaagat tcacctatta caacataatc
      121 aggttgaaca gccttactta tctctctagc tgaaacacct tcaaatattt cttcatgaac
      181 aacacctgct acatacaatt caccttcaaa gtctttgtta gtatcttctg caaagtatga
      241 aacagcagcc atcatagcac ttacttgccc cttcatatca gaagttcctc taccatatat
      301 tttcccatct actattctcg cttcaaaagg aggaacactc catttacttg catctggaac
      361 tggaactgta tctatatgcc cgtcaaataa tattttttta cctggtttat ttccttttat
      421 acatcctact atatttccat atctatctct tgaccaacta tcaaaaccta gtaaagcaaa
      481 attttcttct atagctttta ctacgttttc ttcttgacct gaataactag catttcttat
      541 taagtcttgg catacttcag ttaattgttt ttttcttgtt tcatttaaca ttttgatatt
      601 cccccatata atttttaatt tgttgacgtt ttattttgat atttcatttt tttaatttat
      661 tagcatttca cttaatctat tgatttttta tttctttata ttttatttat taaattttta
      721 tttagacttt attttaattt tatttggttt ttattttgaa tttttcattt gctttacttt
      781 tttatttgct ttactttttc atttatttag atttttcatt tgttttagtt tttattttat
      841 ttaaagtttt cacttattta agtttttatt ttccttaaat ttttcattta tttgttaaga
      901 ttttcttttc cttaagtctt ttatttactt tggcattcac cattccaaac tatatctcta
      961 tatttatcag ggtcagtatc tccttctgta cttattaata atactttaga gttctcatct
     1021 agtttcaaag cttctcttaa gtcttttaaa tcttcacttt caaggattga aactaatgct
     1081 ccagttgtaa ctgctccaga ttctccagag attactttct catctcctct tagagggttt
     1141 cctaatattc tcataccttt agcagatacc cagtctggtg ctgaaacgaa tgctgatgaa
     1201 taatttttta acacttcaaa acctatagtg tttggttctc cacaagcaag ccctgccatt
     1261 atagttggca tatctcctcc aacaaatctt ggttttccat ctccagcttc tgctgattta
     1321 tagtaacagt cagcctcatc agcctctact actactgtta ttgggcattc atcatatatt
     1381 gaagcaacat atccttgaac tgcaccagca agtgaaccaa ctcctgcttg aacaaatacg
     1441 tgtgttggtc tatctactcc atattctttt aattgttcta tagcttcttt agccatagtt
     1501 ccatatcctt gcattatcca tgctggtatt tcttcatatc cgtcccatgc tgtatcttga
     1561 accattactc catggtcatc agcttctgca taatcattag ctaatcttac tgcatcatca
     1621 tagtttaagt ctgttatact agcatctgca ccttctcctt tgattttatt taatctaaat
     1681 tcagaagaac cttttggcat taatacaaca gatttttgac ctaatttatt agctgtccaa
     1741 gcaactcctc taccatgatt tccatctgta gctgtaaaga aagttatttc tcctaatttt
     1801 tcttttattt cttttgaagt taatttatca taccctaact cagatatatc tgtatctaat
     1861 ctttgagcta agtatctacc catagagtaa gaaccaccta aaactttaaa tgcgtttaaa
     1921 ccaaatctat aagattcgtc tttaacatat attccgctta cgcctagtga ttttgctaag
     1981 ttatctaatt taactaaagg agttttttca tattgtggaa agctttcatg aaaagcttta
     2041 gcctttgcaa tctcttcatc ttttaaaaat tcaattcctt tttctttttc ctctgattta
     2101 ggtaagttat ttaatttcca ttttatttct ctcatttatt ttatattccc ctttcaaatt
     2161 tttcggtgtc attttaattt tttatctttg tgccttatag caaagcaatt accgtgccaa
     2221 tattatttat tctaaaaaca atttttttat gttggaatta catactttta taaaatttct
     2281 ttaaagttta taaattttga gtgtgaaaaa taagatttat aaaagaaaaa attctcatat
     2341 tgggaaattt ttatcaatac gagaattatc aattcgagaa atcgtttatt tatcttaatt
     2401 cttcctttat tatgctctta ttttttatat gtctattgtt ttgtcagata tattactact
     2461 tttattttct ataaatatat ggctataacc ttcttacgca taaactctat aaatttatat
     2521 actttatatt ctttattacc caaatattct ttattaccca aagcctccaa aatggcttaa
     2581 atcttttcat agcttcttac agaagtttac atgggcgtcc ccccaataag caaaagtgca
     2641 atatgtgtac cattgtgccc tacttgcgac tattgagctg tcgaaattcg caacttcgca
     2701 tttatctgat gaaatgcact atacaaaata ttcataacat ccacaacaga gttaaagtta
     2761 cctattcata ttcactgtaa aaatttcttc cacaggaaat gtaattttaa ccaatcctat
     2821 tgagacaaac tcaccactta tttttttgaa ctcacgcagt aatacatcac ttgcccgaaa
     2881 aaaagcctca ctttcatcat ctccagtaag tgctattgtg caatggggta cccaacgatt
     2941 ggggtggtac cattcccaac catttgaatc aaaatcttgt agtacctcat ataattctct
     3001 ctgaaactgc tacatactgc tattcattat aggtgataca aacaccgttt tagtatcatt
     3061 aaacatgcct actgaaccaa tgtaagcagg tattacctta tggttttgtg caaacccctt
     3121 tagcttgtct atacaacaag cctcatccac atcattgaaa caagccaaag taagatgagg
     3181 tcttgttttc cattctaaat acttcgtact aattttttca tcagcgattt ttttagataa
     3241 atcaaaaagt tgcttttccg tttttttatc ataatacagc tctatcgcat attgcataat
     3301 aacacctcca ccataaagta aaaataccta tctataaaaa cacacaaata cctatcattt
     3361 taatattata ttactactgt tcctcttcca attttctata tagtgtagcc aaacctatgc
     3421 ctaagtcttt tgctatcttc ttcttcgtct ttgtatctct tccatactta ttcaacaact
     3481 tgtttatgta agtcaactct aattctttaa ttgaaagtat cctttcttga ttctctacta
     3541 tccctccaac tatatcatct tcaaatatta tatttacatc cttattttta taaatatttc
     3601 cattaatatt ataatagttt aaaatatcta atggaagcat atctttatat attattccat
     3661 catctccaac caaattcatc atatattcaa ctgcattttc cagttccctt atatttcccg
     3721 gccaattata gttaatcaac atattcatta cattttcttc tattttattt aactgaatac
     3781 ctaattctaa agaatattta gaagcaaact tcatcattat tgcctcaata tcatcctttc
     3841 tttccctaag aggtggcaaa tttataggaa ttacattcaa tctatagtat aaatcatccc
     3901 taaacttacc ttcatttact aatttcaata agtttttatt tgtagcagca atcactctta
     3961 tatctaaatc tataagttta tttgacccaa ttctcgcaaa ttttctctct tgtaaaactc
     4021 taagtaactt tgcttgtaaa ggcattgaca aatctcctat ttcatcaaga aatataacac
     4081 cttcatttgc aagttcaaat ttacctactt tacctccact actagctcca ctaaatgcac
     4141 cttttatata gccaaatagc tcactttcaa ggagattttc tggaatagca gcacagttta
     4201 tcgcaataaa tggcttgttc catctgctac cttcagcatg tatagcccta gcaattagct
     4261 ctttacccgt accactttcc ccagttataa gtacagttga atttgacttt gctaatttct
     4321 tagttctctc ttttactttt aacattgctt ctgaatttcc aattatagac tctatatcac
     4381 tatttcccca gccactattc acttttccat gtcctttatg attgatatat gtcttgtcaa
     4441 atattattat tttgtcgtat tgatttatat atggatatac cggaattatt ttggcattta
     4501 tattataaat tttgttatca atatcaattt ctagtaattc atgtccattt gaggaagatt
     4561 caacagatac tatatttact atattttcta ttatattttt atctatatct aattttttta
     4621 gagctatatt gtttatataa gatattttgc tatttatgtc tagtattata acgccttttt
     4681 caacattttc aatgatttct atcatcatat ccatttttct actgctattt tttgacgctt
     4741 catgttcttc tattttcata gaaattaaat cgcatatatg attgacaaat tttaaataat
     4801 tatctatttt tgcacttatt tctacttttt tagttttatc tgtactaata gcaccaatta
     4861 ctcctatagt tcgattatta tactttattg gaactgctat tattacttta tttaggcatt
     4921 tcatgtaatg ggaacattct atacaaagct gattatcaca tatatccaat acgactaatt
     4981 cctgacctgt ctgtataaca ttgtcataaa taaagccctc agtaacaacg ctttcattta
     5041 tctttgattt atacagacct gtaccactaa ttcttattaa tctatcgtca actatttcaa
     5101 tatctacatc taacacacta gctactgttt cagtgtattt tatcatttct tgttgaaatt
     5161 cttttaattt acttaacata gtttccccca ttagaattta atttaccaaa ttatcagttt
     5221 agctatattt taacatatag tcactcttta aaatatatat aaaacattac ttatttatat
     5281 atttgcgtta aaacagacaa tattaattta taaaaagttt gttttatata gtaaccttaa
     5341 ttataatatg cagacaataa aataaatcac aatacaataa taaaaaaaag ctttcctcat
     5401 ataacaaata tatttttgac ataaaaatat acattatatg agaaaagctc aatagttaaa
     5461 tatttagata gatttttata tagacttttt taatataaac ttttttaatt gtagactttt
     5521 tttattagtt tttaattttt attagttttg ttattggttt tattgttata atacttataa
     5581 tactgccatt gcttcaattt ctaaaactgc atcttttggt aattgagcaa cttgtacaca
     5641 tgaccttgct ggtggatttt ctttaaaata tgtagcatat acttcattaa tatcattaaa
     5701 atcctttaaa tcttttacga atactgtagt cttaaatatt ttatccatac ttgtaccagc
     5761 ttgttctaat attgctttta cattatctaa agaagctttt gttgcttctt ttgggtcaga
     5821 tactaactcg ccagtcttca tatctattgg aagttgacct gatgtagaaa ctatgtttcc
     5881 aacttgaatt gcttgagaat atggtccaat tgctcctgga gctttctctg tagctattac
     5941 tacttttgac atgacttcac ctcctattat taagttatat ttacaggaaa ataaaatttc
     6001 ctaaacacca atattaatac gaacctttag attaaacttc aaatctaaaa cttcaaataa
     6061 tcaatactta gatgattatg tttatttgtg tcttgttaac ttttattaaa gcaattaacg
     6121 tgccaaactt tatttatata taaaattttg tgaagtcatt caaaatagtt acttctgaat
     6181 tttttcgtaa aaaaacgctc taaaattact tttttatgat gtcaattttt ttctcatatc
     6241 tagaaattta ccaacatgag aattcttgtt ttgagaattt acagattaaa gttatttttt
     6301 aaccttaaat tctgaacctc ccatgactaa agtcacaggg ttcctgcttc atagaatttt
     6361 gcataatcaa gttattacat atgaaagaac tatagttgac aatcccacta ttataaataa
     6421 taaaaccttt acccatacct tatttaccct agttatcata gagcctattg aaaatataac
     6481 agctaaatat aataataacc aaaaaattat caatatctac cactgttgct gaaaatccaa
     6541 aaaactacct tttgatagta ttacttaaca atctaattaa tctcataata aatttacaac
     6601 ttataaataa attgttatat tggccgtatc tcaacaactt tctcctttcc tagttttaaa
     6661 tcttttatag aattgtacca cgtctaagta aattttcata ctattaagtc ttatttctaa
     6721 taaatcatta gctctcattc tatgcccaat aatgtaagat tgcagtaatt ttattgattt
     6781 taatagtttt atttaatata cttatattaa ttattttcat atgaaattat tatttatata
     6841 gggggatttt tttaatatga gcaaaagtga attaacagca gaaacaacag aagaaatgtt
     6901 agaagtacta agtggtaaag attatgatat tgcatgtcat ttacatgaac ttggtaaatc
     6961 attagattgt aaaattgaac caaaaacagg tgctcgttct tacaaaatag tatattcaac
     7021 taagaaacca aaacgtagct tatttactat tgaatgtaat gaaaaaaaat ggagagttaa
     7081 agcaaatctt tttcatctaa atacatataa agatgctgtg gaggaatgct ctaaaactat
     7141 taaagatagt ataactaaaa ctcgtacttg taagaaatgt aattcaaagt gtattggagg
     7201 ttcttcgttt gaattagatg gaaagtctta cctgacttgc ataggaagtg gtcattattt
     7261 tgcaaatatg gaagaaatgg attggaaaaa cctagaaaaa ttaattacta aagaaaataa
     7321 tattatgcag gaatctgtat agttttttaa gggtaattat taaaatatat gagtaacaac
     7381 agatacttaa ataggcataa aaaaataaag ggtataataa ggatatagaa taaaaataaa
     7441 tgatatagca caaagaggct gtctcaaaat acagataagc ctctttttat tgttgaaatg
     7501 ataagaatat attcaatttt atacaatttt atacaaacat actacgccaa cttacccatt
     7561 tcatatgcct gtttcattgc cttacttccc ttaatatcac ctacattcca agcacctaca
     7621 ccatatacta tacctttttc cttagaacca tttagacatg atgtaaatcc tctaaatcct
     7681 tctattgttc tttccatatc agccacattt tcatctgctg ctgtaacgat aaaatagaaa
     7741 tctttatcac aaatttcagt atatctagag caagttctat caatcatagt tttcatttgc
     7801 gcattcatag tataaaaata aactggagtc gctaaaacaa tcacatctgc ctcaatcatt
     7861 ttttcaagaa tttctcccat gtcatctgtc tgtgaacaat ttgcttcttt ttcataacaa
     7921 gcaccacatc cagtacaata gttaatatct ttatctttta aaaatatctt ctccacttga
     7981 tttttagatt ctaatacccc ttgtataaac tggtcacaca ataaatcaga atttccacct
     8041 tttctaggac tagctgatac tattaataca tttttactca taagatactg cctccatttt
     8101 cttatttcta ctgctcttta atactttttc tttctcaata ataccttctt catatctatc
     8161 aatcttaaaa tttaatcgtt ccaaagtttt ttgcatttct tctattcttt ttgctagttg
     8221 gtttctctgc tctattaaaa gttcttttct agctttgata gtactgctcc cttgttgaaa
     8281 catagctaca tactcaatta atgtctcaat agaaagacct gcacctctca tacactttat
     8341 gaaattaacc cactcacaat cttcttctgt aaaagaccta attccacttt tatttctatt
     8401 tacaggtggt attaaaccaa ttcgttcata atatcgtaaa gtatccgctg aaagctcgta
     8461 ttttttacta acttctgaaa tcgtcataca tatcttctcc tcttgatatt gtatagattg
     8521 aattatttct caaaggtttc tgctacattc tttaaagcat ctataatttt aatgtgttga
     8581 ggacagcttt cttcacattg tttacattca atacaatctg aggcctttcc ataagtttta
     8641 gtataattat tatagtagac catctgtgtt gaaaatccag tattaagagc ttgtttttct
     8701 gcattgtaca acgcaaaata gtttggaata gcgatatttt ttggacagcc ttctacacaa
     8761 tactgacagg cagtacaagg aactaaaatt gattcgttga taatctctac tgcttcatct
     8821 ataatattat attcctcttg tacgaatggt ttgaaatttt gcatatatcc tgtattgtct
     8881 aataattgtt ccatatttga catcccactt aagaccatca taacattatc tttacttgct
     8941 gcaaaacgta ttgcccaaga tgaaattgac atatctggat tgtagtcatt caataatttc
     9001 tctgcttttt ctggtatctt tgcaagtgta cctcctttta ctggctccat aacaattaca
     9061 ggcttattat gcttctctgc cacctcgtag cattttctag attgtatgct ttcattatcc
     9121 caatctaaat aattaatctg taattgcacg aagtctactt ctggatgctc actcaagact
     9181 ttatccaata attctgcact atcatgaaaa gaaaaaccaa tattctttat ttttccttct
     9241 tttttctttt cttcaataaa cttaaagcta tcaaattttt tagctacttc ataatgtgac
     9301 acgcctatat tgtgtaaaag atagtagtca aaatagtcta caccacattt ttctaattgc
     9361 tcattaaaaa tggtttcttg ctcttctttt ttctttaaag ccattaatgg aagttttgta
     9421 gctatagtaa aactctctct tttgtgtctt tttactagag attctctaag tgctatctca
     9481 ctttttccca tgtgatacac ataggctgta tcaaaatatg taaatcccct ttctaaaaaa
     9541 gtgtctacca ttttatttaa atgttccata tcaatagttg taacatcatt ttcatctttt
     9601 attggtaaac gcattaatcc aaatcctaat ttttttgcct ccattgtttt acttccccct
     9661 ttaaaacttg tttgtttttt ctctctactt taactattct tacaagtata taattcttgt
     9721 ataattatac tttactactt ggagttaact tcaagtcaat agattttttt atttttaaga
     9781 caaatattat aaaaatacag ttctttaata ttaatccatt acatgtttct ttcaccctcc
     9841 aattctcaaa cttcacaaac tccaacatgt aaagaaatat atactttaag aaattcagtc
     9901 cattaatatt actacaaata ctttttagat atgtttaaaa agaaatttca cctaaaagat
     9961 ttagaaatag gtcttgtgtc tattttaaaa tatataaaac agtggtaaag acttatttat
    10021 aagataaaaa atgaatagtg tatacccttt ttaaaaagtt ttttcctttt tatatttgtg
    10081 atacaatgtt aaatataaaa aggaaaattt tgtattaaaa aaatcttatt tgttgatttt
    10141 gtaacttcaa actcagcatc aatttgattt taagattata ttttattaag tatgctaaat
    10201 aacaaatttt taaagattgt gaggtaaaaa tatgaataag aaaaatttag ctatattaat
    10261 atcaggtatt atgttttttt ctagttcttc agcaattttt gcagacaata ctacaaagca
    10321 agaaagatta ataggtaaaa caagatatga aacagcagta gaagtaagta aattgggatg
    10381 ggttcaatca aaaacagcca ttatagttaa tggtaattct attcaaagtg cgctttgtgc
    10441 aaatccattt gctaagctaa agaatgcacc tatactttta gtaaacaaca acagtattga
    10501 aaattcaact aaggctgagc ttaaaaggct tggtgtagat aatgtgtaca ttgtagatag
    10561 tggaaatagc atttcttcta aagtagaaaa tgaaataaaa tcacttaaca taaaaataaa
    10621 taaaatagta ggaaacaata tatatgaaat gtctacaaat gtacttaaag aaatagataa
    10681 gataaaaaag gtagaaaatg ttgcagttgt aaatggacta aagggactat ctgatgcagt
    10741 tagtatagct tctccagcag caatacataa tatgcctata atattagtat cagatgaaaa
    10801 cagcaatgat agtagtataa atttcttaaa caataggtct ataaaaaaat cttacatagt
    10861 tggaggaaat aagattttat cagacaatac agtaaagaaa tatccaaaca gagaaagaat
    10921 cagtggttca gatagaaaca atactaatgc aaaaattatt gataaatttt ataaagataa
    10981 aaaaataaat aatgtatttg tagctaaaga tggtattaac caagaaaatg cattagtaga
    11041 ttcattatca ataggagtac tagctgctaa agaaaattct cctataatga tatctaatgg
    11101 tagccttgta aatagtcaaa aagaatttat taaaaataaa gatatagatg aaataacaca
    11161 agtaggagga ggatataatc aaaaagcatt tgaagatatt ttaaaactaa aaaatgtgaa
    11221 cataagaaat aaaactaaaa aaatatcttt aatacaggct aaagaaatat taaaacaagc
    11281 tcttccagga agcaatattt tagtttgtta ttatgatgaa gatgataatg aatatgactg
    11341 caaagttata aaggataata tcctatatga gatagaaatt gatgcctact ctggtaaaat
    11401 aatagaaatt gaaaaagatg atgacttaaa tgataataat ttaggtacac aaaatatatc
    11461 attggataaa gctaagtcta tagcattaga tgctgttcct aatggtaatt taatctattg
    11521 taaatatgat gctgaagata acgaatatga ggctaaagta ataaaaaata agaaaacata
    11581 tgaattagag ataagtgcat ttgatggaag aattgtagat attgacatgg acaatgattc
    11641 tgatgatgac tttgatgata atgataagaa taactctaat actaatgaca acagttctat
    11701 tattagtgct gaaaaagcta aatcaataat gctagataaa gtgcctggtg ggaaaatagt
    11761 aaaatttaag tatgatgaag atgacaaaga atatgaaggt gaaataataa aaggaaaaac
    11821 tgaatatgag ataacaatta atgcaattac tggtaaaata ttagaatttg aaatagatga
    11881 ttaataaaaa atatatattc tattaattat tacaagcaat aaagccat
//
LOCUS       DAYAKB010000101        11687 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.102, whole genome shotgun sequence.
ACCESSION   DAYAKB010000101 DAYAKB010000000
VERSION     DAYAKB010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11687
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.102"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            392..1069
                     /locus_tag="ACGI3L_003286"
     CDS             392..1069
                     /locus_tag="ACGI3L_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198981.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            1141..3156
                     /locus_tag="ACGI3L_003287"
     CDS             1141..3156
                     /locus_tag="ACGI3L_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9198982.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLYFL"
     gene            3206..3886
                     /locus_tag="ACGI3L_003288"
     CDS             3206..3886
                     /locus_tag="ACGI3L_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9198983.1"
                     /translation="MQTKILIIDGDKDNCKKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            4404..4850
                     /locus_tag="ACGI3L_003289"
     CDS             4404..4850
                     /locus_tag="ACGI3L_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9198984.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIHTYCKHQVS"
     gene            5231..6148
                     /gene="pstC"
                     /locus_tag="ACGI3L_003290"
     CDS             5231..6148
                     /gene="pstC"
                     /locus_tag="ACGI3L_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFG9198985.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            6150..6974
                     /gene="pstA"
                     /locus_tag="ACGI3L_003291"
     CDS             6150..6974
                     /gene="pstA"
                     /locus_tag="ACGI3L_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFG9198986.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            6993..7757
                     /gene="pstB"
                     /locus_tag="ACGI3L_003292"
     CDS             6993..7757
                     /gene="pstB"
                     /locus_tag="ACGI3L_003292"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFG9198987.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            7785..8438
                     /gene="phoU"
                     /locus_tag="ACGI3L_003293"
     CDS             7785..8438
                     /gene="phoU"
                     /locus_tag="ACGI3L_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFG9198988.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            8596..9465
                     /locus_tag="ACGI3L_003294"
     CDS             8596..9465
                     /locus_tag="ACGI3L_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFG9198989.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            9552..10988
                     /locus_tag="ACGI3L_003295"
     CDS             9552..10988
                     /locus_tag="ACGI3L_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-Fe] hydrogenase large subunit C-terminal
                     domain-containing protein"
                     /protein_id="HFG9198990.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     NLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            11036..>11687
                     /locus_tag="ACGI3L_003296"
     CDS             11036..>11687
                     /locus_tag="ACGI3L_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9198991.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIV"
BASE COUNT         4569 a         1224 c         2087 g         3807 t
ORIGIN      
        1 ataaacattg agatgcagaa tataaacctt ttgtaacaat atatttacca aaataataca
       61 atttatttta tattataacc atataaatca tataaatcaa tactcaaact agccaataga
      121 caagtttcta gaaaaataat aaatttatac gtgaaaatga ctttaagctc cattctccaa
      181 caatcggaga ctttaattag tatttaataa tgaatcttaa tgtttaatac aatattcaag
      241 aattattcaa aaatacttaa gtattatagt ctagtttgta aagatattat aaaataataa
      301 taccagttat atatgaaaat aaaacattat aatttgtaat aactataaaa cttggaatta
      361 taattaaaat acctttgaat ggagtggtgt aatgtataat ttactggttg tagatgatga
      421 tgttgatatt ttaaacataa atcaaattta tttttctaat ataggtttta atgtatatac
      481 atcagagact gctaaagatg ctatggatat agtagagagt atagttttag actgtataat
      541 tttggatatt tcattgccag atatagatgg atataaaatg tgcaatgata taaaagaaaa
      601 ggttaacata cctataatat ttttatctaa ttatgagcat gaagaagaaa aagttcgggg
      661 atttttagct gggggggatg attatataac aaaaccttat agtttaaaag aacttgaact
      721 tagaatatat gctcgtatga ggcagtacaa aaatattaca tcagttccta atgtgttaaa
      781 gttttcagcg ttagtaataa atgtaaattc aagaaaagta acttttgatg gagaaagtat
      841 agatttaact actatggaat ttgaaatatt attgtttcta gctgaaaaca aagaacaagt
      901 attttcgaag atagagatat ataaccaagt ttggaaaatg cctgatattg gagatcaaca
      961 tacagtgcag gttcatattg cacagatgag aaaaaaaatt aattctttaa gcagggagca
     1021 tcaatacatt caaaccgtat ggggaaaagg atataagttt gtaccataag tgagatactg
     1081 taattaataa atagttcttg ttttatttaa tactactatg aaagagatgt ggttgataca
     1141 atgaaaaagt ataatatact aaaaggaact ctcattgtat tgatagtctc tctgttggca
     1201 ataacaggat taaatcttct gtataaatat gataataaat atacatataa gtctattaga
     1261 gcaagtaatg gaattttaac tatagataat gatactttca ctaaaggtaa acttgtcttt
     1321 ttgatagatg actgggagtt ttataatcat aaaatattta aaccgaatga ttttacagag
     1381 caagatataa aaccagaata tgtttttata ggtcaatatc cagatttttc tatgagaaag
     1441 gggactcagt caccatatgg gaatgctact tatcgtatga gaataaaaaa tgaaggcaag
     1501 gataagctac taagtttaga gcttcctgag attttttccg caagtgaagt atggataaat
     1561 ggagaaatgg tttctaaatt aggagatgta ggaacagaaa aatatagacc caaaattaaa
     1621 aattcagtag taagttttat tgcaaagaaa aatacagaaa ttataatcaa tgtatcgaat
     1681 ttttcacatt attatagtgg tttgtattat ccgcctgcat taggagaaac aaaggacata
     1741 agtaatatga tgttttatcg attacttttt tatagtataa tttgcttcac aacttttgca
     1801 atagctatat tttcattgtc tgtatggttt ctttcaaaca aaagtaaaat ttacttatat
     1861 tttggatgta tgtgtgtttt ctttgccatc catgtatcct atccctttgt acatttgtta
     1921 ggactgcctt tggtaagctt tacatatgcg gttgaagatt tgtcatattt tatggtagtt
     1981 ttatgtatta tttgtataaa tggaagtata tccaaaatag aagaaaataa agtgtacaga
     2041 tttttaattt taccattagg aattacaatg agtatcatat ctatagtgat accaattatt
     2101 cttcttccat atgatatgta ctttgtcaac atatatggga agttaataga catatataaa
     2161 tatattgtat ttatatatat attaatgtct tcgctggttt caatatataa aaagacatgc
     2221 tctgagcata taagttctta tattttagtt tcagtaaaca ctgtttttgg aattagcata
     2281 ttatttgatg cagttacgag taatagattt gagcctatat ttacagggtg gcaaacagaa
     2341 tattgtgggt ttgtaattgt tattttattt tctgttatga tgataaacag gaatagaata
     2401 ataataaaag agaatgaaaa acttacaagg aatcttgaac atgaagttga agtgagaact
     2461 aatgaactta caacattgtt aaatgaacgt aaaagattct tggcagatgt agcacatgat
     2521 ttaaaggcac ctgtttcggc tatacaagca tttatagatt tgataaaggt tggtaatatt
     2581 catgtagatg aagagacaag aacctatctt tatgctataa atcaaaagtc aaatgaagta
     2641 caaaatagag tacgtagttt gcaagaattt acatcacaag ataaaagcat tggtattagt
     2701 gaaaaaatat gtctgaataa ttttattaaa gagatatatg aaaataattt gccagataca
     2761 caagcatgtg gtgtaaactt tgaaacttac gtattggaga aaaaaatata tgcaaagata
     2821 aataaagaga tgcttacaag agcatttgag aatttaattt ataatgcttt gacctttact
     2881 ccatttgatg gaaagataat tttatcaatg gataaagaag atggatttgc aattattaaa
     2941 atttctgata atggaaaagg tatacctcca gaaaatatac caaaggtatt tgacagattc
     3001 tttacagaaa gagacaataa tgagccaaaa gggcaagggt tagggctata tattgtcaaa
     3061 tccattataa gagagcatgg tggagaaatc tttgtagatt cagaactagg aaaaggaact
     3121 gtttttacaa taaaattaag tctatatttt ttataataat agcttattta atataaaaga
     3181 ataatgatat ttgggagtga ttataatgca aactaagata ttgataatag atggagacaa
     3241 ggataattgc aagaagctaa aaggatttct ggaggaaaaa ggaataagta tagatttagc
     3301 atataattgt gaagaagcta ttggaaaaat atttagcaat aaatatgatt taatattttt
     3361 agaaataatt ctaagtgatg gtgatggatg gactctttgt aaaaaaatta gaaatgtaac
     3421 tacttgtcca attgtttata tgacttatat aaatgaagac caaagcattt taaatgcttt
     3481 aaattctggt ggagacgatt acttaataaa gcctctaaat ttagaaatat tatacgcaaa
     3541 agtaaaagct attttaagaa gaatgaactc atatgtaaat aataatgaaa ataatacaaa
     3601 attagaggaa tataatagaa ctagtggagt aataaagtta gaagataaaa taataaaatt
     3661 gactccaaca gaaaataagt tgttaaactt ttttatagag aatcctgaaa agactttgac
     3721 tactaaagag atatatgaac atgtatggat gaatgaatac ttagaggata actatagtgt
     3781 ggtagttgca gtgaatggat taagaaagaa aatagagaaa gattataaaa atcctcagaa
     3841 aattataaca ataagaggag caggatatta ttttaataaa gaataataaa tatattaata
     3901 tcattaataa ttgttataaa tgtgaaatac taacaatatc taaactaaat tattataaaa
     3961 tagctgactg taatttaatt gataaagcct attcttctag actttgccag ttaaattaca
     4021 gtcagtttta ttatataaaa aaatgcgtaa tggaactatt attttataga ttatatttga
     4081 aaagatagat aaattgtata tctaaatcta tatattattt ttttaccttt aatatatatt
     4141 aaataataaa atagttaaat aataagatta agaatttctt aataaatcca gaagatgctt
     4201 tcgattatat aatattttat atttttatat tattaattat atatgttgca attgctgcac
     4261 ctactttttc tggtgagtat cagacacaat cagatagcat ccttcgttgt acgaaacatg
     4321 gacatatttg tctagcgttt actaaaatat tagctctatt ttctatattt ataataatgt
     4381 ttgttatatg tatttctatc tatttggcaa tttctgattt agcttttggt actgaatgtt
     4441 tgaaaacctc atttcaaatg ttgttttctg tcattagtct agtaaatata aatttactac
     4501 aagcacagat tcttatagct attggtggtc taatttcaat acttgcaatg gttagtttaa
     4561 cattattttt atctgcaaaa tgtaaggatt ctcttacttc tatgctgatt gctttttcta
     4621 tttgcttaat tcctatggga ataggtgtta gttggattgg atacctatta ccgccagggg
     4681 gaattggttt taagattagt ttattatatc aaatgacatc atttaatttc ttacacttag
     4741 gaggtatgag tttttggaca ccacacatta tactgttttt ctcagtgata gaaataccta
     4801 tttttatatt tttggctatt catacctatt gcaaacatca agtatcgtaa caatttgatg
     4861 gaaataatag tgatataaac tagaggatac aataattata tatgtagtat aaaagttaaa
     4921 tttagttaac aaatcttaat agcagatata ggtaataaat tatacataaa ctgtattatt
     4981 atctatatct gctattttaa tatagagaaa caacagtata ttgtaaagta aatgtcaaat
     5041 atagttttaa aagtaaaatt aatgttaaaa agtaaatata attttacact tgcttaactt
     5101 aatcctaata tagatttaac ttaaaaaaag tagaataaaa gtacaggaaa tttgatgaag
     5161 acgaattata aaaaattaaa ttttgaatac agaacgaaaa tcgataagta tattttaatg
     5221 ggagggtatt atgatagtaa aatctagatt agtaggttta gaaaaaaatg acaataatgg
     5281 caataagaca aaatacgtaa ttgaaaaagt agcaaaaaat atttttctac ttagtgcttt
     5341 agtagcagtt gcaagtttac ttttgataat aggatttgta ttttataaag gattaagacc
     5401 atttatattt gaaggatatt catttataga ctttttaact ggtgcagatt gggttccttc
     5461 tgccaataaa tttggaatat catctatgat agtagcatca atatttgcaa cacttggagc
     5521 acttgttata ggagtacctg ttggtatatt aacctctgta tttatagcag aagtagcacc
     5581 taaaagatta gcaaaaataa tgtcaccagc agttgaactt ttagcaggta taccttcagt
     5641 attatatggt gtatttggtc ttgcagtgat agttccaact atacaaagta tatttaatct
     5701 tccaaaaggt caaagtttgt tagcaatagt aatagtatta gcagtaatga tgttaccaac
     5761 aataatatct gtatcagaaa cagcaataag agcagtacca aaagcataca aagaaggttc
     5821 attagcactt ggtgcatcaa aaatagaaac aatattcaaa gttgtattac ctgctgcaaa
     5881 atctggagta ttagccgcag tagtgttagg agtaggaaga gctttaggtg aaacaatggc
     5941 agtaatactt gttgcaggca actcaccagt tatgccaact gcaataacag atagtgtaag
     6001 accacttaca actaatatag cacttgaaat gggatacgca tttggtacac atcaagaaat
     6061 gctatttgca actggagtag tattgtttac atttatatta attttaaact tagttttaaa
     6121 taaactttca aataaggcgg taaattaaga tgagaaagtt caaagagaat ctattgaagt
     6181 cattagtata tctatcagca ctatttacaa tagtatcatt agtagttata gtgggattta
     6241 tatttataaa gggaattggc aacatgaatt ttaatttctt atttagcaat tattcagcat
     6301 caggtgatgg tggtatactt ccaatgataa ttacaacatt atatacagta gtagtttcta
     6361 tagttgtagc aactcctata ggaatattgg ctgctatata tttacaagaa tatgctaaaa
     6421 aaggaaaagc agttacagct ataagatttg caactgaaag tttatcaggg ataccatcta
     6481 tagtatatgg attatttgga ggaattttct ttgtagttac attaaaaatg ggatattcca
     6541 tagttgcagg ttcacttaca gttgcaataa taatattacc agtaataatt cgtacaacag
     6601 aagaagcttt aaaaacagtt cctcaagctt atagagaatc atcattggca ttaggagcta
     6661 caaaatttca aactttatat aaggtagtac ttccaagtgc aataccagga attttatctg
     6721 gagtaatctt atcagttggt cgtataattg gagaatcagc tgcaatatta cttacagcag
     6781 gtactgtagc caagatgcca ggtggaatat ttgatagtgc aagaacatta actgtacact
     6841 catacttact gactaaagag agtggagata tagcaacagc agccagtata ggaattgttt
     6901 taatagtaat tgtattagca ctaaacatgc tagcaagatt tgttgctaag aaattaaata
     6961 aagctaatta ttaaatttaa gaggtgtgaa taatggaatt aatcgataag ataaaaatga
     7021 gtgtaaaaga tttggattta ttttatggtg ataagcaagc attaaagaaa ataaatatgg
     7081 atataaaaga gaataaggtt actgctttaa taggtccatc tggatgcgga aaatcaactt
     7141 ttataagaac gttaaataga atgaatgact taatcgaaga tgtaacaatt aaaggaaaca
     7201 tttctgttga tggagaggac atatatacct cagatgatgt tataaatctt cgtactaaag
     7261 taggaatggt atttcaaaag ccaaatccat ttcctatgag tatatatgat aatgtggcat
     7321 atggtcctcg tacacatgga ctaagagata agaagcaatt agataaaatt gtagaagaaa
     7381 gcttaaaagg tgcagctatt tgggatgagg ttaaagacag gcttaaatca tctgcactag
     7441 gactttctgg tggtcaacaa caacgtatat gtatagcaag agcaattgct atgagaccag
     7501 aagttattct tatggatgaa cctacatctg ctttagaccc aatttcaaca ttaaaagtag
     7561 aggaacttat agaggattta aaaaaagact acacaatagt catagttaca cataatatgc
     7621 aacaagctgc tcgtatatca gatgaaacag cttttttctt aaatggagag gttatagaat
     7681 ttagcgatac aaaaactatg tttaccactc ctgtagataa aagaacagaa gactatataa
     7741 caggtagatt tggttaaaat atataactat aaaggagtta gacaatggtc aataatagct
     7801 tagatataag tattgatact ttaaaagaac aaacagtgct tatgatggaa aaatgtgaag
     7861 aagcaataga aaagtctgtg acttgtatga tagagaagga tttagagggt gcaagaaaag
     7921 tagtagaaga tgatgaagaa ataaataaat taagagaaga aataagagat aagagtatag
     7981 agctaatagt attaaagcaa ccaatggcaa gggacttaag atttatttat tcattaggta
     8041 atatatctat agagctggaa agaataggag attatgcagc aaatatagct agagaaatgt
     8101 tgaagatagg tggagaggct tatataaaag agctaataga tattcctaag atggcaaaag
     8161 aatgtaagtc tatgatgtct cagactagag aagctttaat cttatttgat gcaagtatag
     8221 cttatgatgt tggaactaaa gatgatattg tagatggatt gtatgaacaa gtacaaattg
     8281 attgtttaaa aataatgcat gaaaactcaa ataccataga ccaaggggta aaacttctac
     8341 ttataggaag ataccttgaa agaattggag accatataac aaatgtatgt gagaagataa
     8401 tttttgcaat tgagggtaaa atggttgaga taggataaaa aactgcttta aagcagtttt
     8461 tttattgtct aaattaagaa agaattgata aaaaaatatg attaatgggt aaatttaaaa
     8521 aattgtgata tactaggaac atattaaata tgaggatgcg tattttatat aaggtgcttt
     8581 ttaggaggtg gaactttgaa acttcaaaag atgggtatga ggactataaa aacaggaatt
     8641 agtgtcactt tatgtatgat tcttggtgac tatttagtag agaatatgtt ttattctctg
     8701 gtagcatgta taatttctgt tcaagataca gtaaaaggtt ctttaaagac gggaatcaat
     8761 agagtggaag gtactatttt aggtggtata ataggattca tatttgccat cattaaagct
     8821 ggagacccat ttttatgtgg tctaggagta atgtgctcaa tatatttatg caatctgttt
     8881 aaaataaagt cagtagtagt tgcctgtgta acctttctgg ctatacatct aggtgtagga
     8941 aatagtgacc ctgtgtatta ttctttacat agggtgttag atacatctgt gggtgttttg
     9001 tttggagtac ttgttaatta ttatgttgct agaccaaatt atctaaatag tgttatagat
     9061 gagtttaaaa agatagaaga actttcaatg ttgcttattg aagataaaat tcttagaaaa
     9121 gaaaatttaa atgtagagaa atttgaagaa gaagtagaaa aattagaaga aatatattca
     9181 aaacttattg atgagttgga ttatagtttg agtgaaacta atatagaaaa aattgagaat
     9241 gccttaagga tatgtagaga aatacatttt catatgcagt ctatagagtt acttgaaaat
     9301 aaactttatt tgaaagagca tacatataaa taccttaaga aaacatataa tgtggataag
     9361 ctagactgga atatagatga agaaaaaagc cctgtattca actatcatct aatgaaaata
     9421 atgattgaaa tagagttgtt gagaaaacta aataaatcat attaataata gtagttaaat
     9481 aataaataaa aaatagtatc tttgtaaata ttaaacatat ataagtttaa tttatggagg
     9541 tactattttt tatgaatact agaaatgaca attctaaaat actagaaata tataaaatga
     9601 agctttttgg cgaacttgta aaagcagtgt ggaatgatga catagaggat attgaaaact
     9661 tacctaataa aattttaaat gaaaatttaa aggataattt aaataattat tttagtggaa
     9721 aatttgataa agatactatg gtaaatttaa ttagggtaac tatgggattg gatgtgacag
     9781 aagatacaga taaaaattta aaagagtcac tacatgaagc tgtaaattta gatgaagtca
     9841 aaagaccaat aatatctgta atatcagatg cttgcaaata ttgtgatgaa aataataagg
     9901 aagatgagtc atgtaagata agaagtaagc atattaattg taatgaggaa gatgtatgta
     9961 gtgcttgtgg tgattgtgta tcaagatgta agttgggtgc aatttcagat aaaatagaat
    10021 ttataccaat gataaaattg ttaaaagata taaagagccc tgtatatgca atagttgcac
    10081 cagcttttgt aggacagttt gggaaagatg taagccctgg taaattaaga actgcattaa
    10141 aaaagatagg atttgaagat atgatagaag ttgctttggc agcagatatg cttactgcaa
    10201 aagaagcata tgattattat gagcatatga aaaaggacga agaaggatgc tttataacta
    10261 gttgttgctg tcctatttgg gttagtttga tacaaaatag ttttcctcaa atattggaga
    10321 atgtatcacc atccgtttct cctatgattg cttgtgggag agctgtaaaa attttaaatc
    10381 cagatgctaa agttgtattc ataggtcctt gtatggcaaa aaagaaagag gcaatgttag
    10441 aagatataaa agatgcagtt gattttgtgc ttacatttaa agagttgcaa gaaatatttg
    10501 atgcattaga gttaaatcca gcaataatgg atgagagtaa tagagtagag gcgtcccttt
    10561 caggtagagt ttatgctaga acaggaggtg taagtaaagc agttaagtta tcagttagaa
    10621 gaattgacaa aaatataaaa tttgaagaaa aggcatttga aggaacaaaa gagtgcatgg
    10681 acggtctaaa gaaagttcta aataaagaaa tagaagctac atttatagaa ggaatggggt
    10741 gtgtaggagg ctgtgtagga ggtccgaagc gtattttaag tgtggaagaa ggtactaaga
    10801 atgttgatga atatagtgaa agtacgaata tggaaactcc atttgataat ttaaatgtat
    10861 tacaattttt aacttctttg ggaatcaaaa gagtagaatc tttaggagaa aaagaagaag
    10921 aaaaggttaa aaaaatattt agtagagata taaaaagtaa taagaaagag aataaatata
    10981 aaaaataact ttttaagtct taaacttatg cttttataaa agggagatat gggggatgaa
    11041 aattaaagat aataaggctg tttttcatgt atttataagg atatttctta tagctgtttt
    11101 aattttaact ggaacattat tggaggaaaa aattaataat gttccagttg aaaatataag
    11161 ttcaaaaggt gaaaatacac tggaactgct ttctcaaagt aatactttag gagaaatcat
    11221 atacaaagca tctcaagaag aaacaaaagg tccaggggct acttctgaaa aagtagcata
    11281 cataacaata gatgatggtc catcaaaata tacaaatgca ctacttgata ttttaaaaga
    11341 aaatgatgtc aaagcgacat ttttcatgct taatcagaat atgaaaaacc acaaggaaga
    11401 agtaaggaga gtcttggaag aagaaaactc aataggtttt catagtgtaa gtcatgatat
    11461 acataagtta tataaaagcc cagaagtaac agttggggaa tttaatacat gcaataatac
    11521 tctacaagaa ataactggtc agagttcaaa attaataaga ttaccatacg gaagtaaacc
    11581 atatatgcca gaaggttcat ataataaact tatggcaaat gattatttaa tttgggactg
    11641 gaatttggat acacaggatt ggaagtcttc tacaagtcag atagtaa
//
LOCUS       DAYAKB010000102        11666 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.103, whole genome shotgun sequence.
ACCESSION   DAYAKB010000102 DAYAKB010000000
VERSION     DAYAKB010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.103"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            289..2199
                     /locus_tag="ACGI3L_003297"
     CDS             289..2199
                     /locus_tag="ACGI3L_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFG9198992.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNVGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(2262..2885)
                     /gene="ytaF"
                     /locus_tag="ACGI3L_003298"
     CDS             complement(2262..2885)
                     /gene="ytaF"
                     /locus_tag="ACGI3L_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HFG9198993.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            3073..3717
                     /locus_tag="ACGI3L_003299"
     CDS             3073..3717
                     /locus_tag="ACGI3L_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9198994.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            3931..4989
                     /locus_tag="ACGI3L_003300"
     CDS             3931..4989
                     /locus_tag="ACGI3L_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HFG9198995.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRSIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            5093..6277
                     /locus_tag="ACGI3L_003301"
     CDS             5093..6277
                     /locus_tag="ACGI3L_003301"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9198996.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMIVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            6484..7197
                     /gene="rpsB"
                     /locus_tag="ACGI3L_003302"
     CDS             6484..7197
                     /gene="rpsB"
                     /locus_tag="ACGI3L_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFG9198997.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            7276..8187
                     /gene="tsf"
                     /locus_tag="ACGI3L_003303"
     CDS             7276..8187
                     /gene="tsf"
                     /locus_tag="ACGI3L_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFG9198998.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            8272..8976
                     /gene="pyrH"
                     /locus_tag="ACGI3L_003304"
     CDS             8272..8976
                     /gene="pyrH"
                     /locus_tag="ACGI3L_003304"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFG9198999.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            9002..9559
                     /gene="frr"
                     /locus_tag="ACGI3L_003305"
     CDS             9002..9559
                     /gene="frr"
                     /locus_tag="ACGI3L_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFG9199000.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDALLSKKEKDIMEV"
     gene            9562..9765
                     /locus_tag="ACGI3L_003306"
     CDS             9562..9765
                     /locus_tag="ACGI3L_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199001.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            9794..10528
                     /locus_tag="ACGI3L_003307"
     CDS             9794..10528
                     /locus_tag="ACGI3L_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFG9199002.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            10541..11320
                     /locus_tag="ACGI3L_003308"
     CDS             10541..11320
                     /locus_tag="ACGI3L_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFG9199003.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         4900 a         1169 c         2033 g         3564 t
ORIGIN      
        1 tcactgtaca aaaacattaa tgacattatt tttattgaca taaatatata atttatggaa
       61 taatattaga agcactgata taagtgttta aataagaata gaaaaggaga agtgttttat
      121 gaaaaaaaat actaacatta atgagtccgg agttaaactt cttaataaat aaggagtttg
      181 atatataata actccttatt tattaagttg ttcgcaaaat aactattatc aaagtaaatg
      241 atagggtgat ttaaaagacg atgacttata aataaaggag aaaaaataat gaatagtaat
      301 acatttgaaa gattacaact aaatgaagtt aaagacttaa taaaaataca ttgtgtaagt
      361 tcgctaggaa aaaatttaat agataaatta actcctagtg ggaatattgg agtagtaaga
      421 aggaaattag cagaaaataa agaagctaga aagataattg aaaatagtaa tcacatacca
      481 cttgaaggat tgtttaatgt aggttctaca atagataaaa ttgaaaaagg aatgataata
      541 gaacctgttg aacttgtaaa tattgaagat tttttaagag gttgtaggaa gatgaaagct
      601 tttatgttag aaaaagaatt ttattcacct acattaagtt cttatgcctt aaatataaca
      661 gaatgtaaaa gtatagaaga tgagataaat tactgtataa aatctaataa agttgattct
      721 aatgctagta aagaattaaa aaagataaga cgaaatatag aaattacaga aggaaagata
      781 aaagatagat taaataaatt tataacatca actgtaaata aaaagtatat acaagagttt
      841 ataataagta aaagaaatga tagatatgta ataccaatta aatcttctta taaaaatgaa
      901 gttaatggta ctatattaga tacatcatca aaaggaaata ctgtatttat tgaacctatt
      961 agtgtttcaa atttaagtac agagttaact atgctaaaag ctgatgaaac tattgaagaa
     1021 tacaaaatat tatcttattt aacagaactt atatttgaga agataagtca gataaaatta
     1081 aatatagaga tactttcaga atacgatatg gtatttgcaa aagctaagta tagtcaaaaa
     1141 ataaaaggaa ttactccaaa aataaataat aatggctata taaaaataat taaaggtaaa
     1201 catccacttc taacaggaga tgcagtacct ttagattttg aaataggcaa aaattataga
     1261 agtcttataa taacaggtcc taatgcagga ggaaaaactg taacccttaa gactgttggt
     1321 ttactaactt taatggttca atgtggattt gatatttctg caaaagaagg tagtgaattt
     1381 agtgtatttg aaaaagtttt tgtagatata ggggataatc aaagtattga aaatgcctta
     1441 agtacttttt catcacatat aaaaaatatt gcagagatta tgagtttatc aaataattct
     1501 actcttgttc tgtttgatga aataggaagt ggaactgaac ctaatgaagg agctggttta
     1561 gcaatatcat tattagaaga gttttacaaa atgggatgta taactatagc atcaactcat
     1621 tatggagaga taaaaaagtt tgctacattg catccagaat ttgaaaatgc tggtatgatg
     1681 tttgataaag aaacgttaga accattgtat aagttaacta ttggaaaatc tgaagatagt
     1741 aatgctcttt ttatttctaa aaaaatggga ataaaaaata gagttttaga tagagctaaa
     1801 gaatatgtaa ttgatagaaa ctacaattta gatttagtta aaagaagtaa gctacaatct
     1861 aatattgaag ataaaaatag ttctgaagtc attttaaact atacagatta taatgtaggg
     1921 gataaggtaa aattactaga tgaagatgat tttggaattg tatataaacc tatggacaag
     1981 tttaataatg tagaagtatt gtttaatgat aattttattt cagtaaatat aaaaagatta
     2041 caacttagca taaaagcatc agaattgtat ccagaagggt atgatttaga tgtattattt
     2101 actagtttta aagaaagaaa attagaaaaa gatattcaaa gaggttcaaa aaaagctctt
     2161 aaaaagattc agaaagaaat tagagagaat agaaaataaa tataaaaagc acaaaagaaa
     2221 gcaatctaaa gagaaaagtt tatctttaga ttgctttctt attaacatat cttcataaat
     2281 ccaatgacta acaagattaa accacttaac caagataagt ttaaatttac gtttttaaca
     2341 aacatatttc ctagtaaaca accaagtaat actgcaatta tatttgatat taaagaaaat
     2401 agaataactt gtatataatt cacacctaca aggccactac caaaaccgat agctaatcca
     2461 tctaaactta aagcaagtgc aagtgtaaat gcttcagcag atttaagcac tttagattta
     2521 cttgtatcta agacatcagg ttcgatactt acattaaaat ttaatttaag gtctaacata
     2581 ttaaaattat aattctttga gtgtatagat tttttcttaa aataagattt aaaaaaactt
     2641 tcaattagtc tagcacttcc taataaaaat aaaataaaga aacatattaa cattgttata
     2701 ttttgaggta aaaagtctct aactattgta cctgcaaaaa gcgatattgc taaaatagct
     2761 gaacaaacta cgctgataat tatatttgaa tataagggaa ctttaacttt atttacgcca
     2821 tatccaaagc ttgtcacaaa ggcatctata caaagagaag taactaataa aattgattca
     2881 atcacagtag attaacatcc tttctcttaa attttgtact tatattagtt atagtattgt
     2941 aaaaatggat aaattgttac agataatcca ataaattgtt gataaaattc caacatcata
     3001 caacacctaa ataacaaaag aatcatatca tataataata taaaaccaat cataataaag
     3061 cgggtgaaaa taatggaaca aaataataag gttgggaatt tcggtgattt gttgaagatt
     3121 ttattagatg aaaaagaatt atcaatggga gaactaagta aaaaaagtgg aattgataaa
     3181 tctactatat ctcgtatagc taataataaa caaaagccaa atataaatca tttagaaaag
     3241 atggcaatac atttaaatat taacctagaa gaactgttga aagcttcagg atatgaattt
     3301 agaaacagca ataatcaaat atttaatgca gatagtgatt ttagtaactt tgatgatatt
     3361 cttggatttg caaatttaat caatgataag aactttaatg gaaatattga aaaagagtta
     3421 agtaagtgta agttatatgt ccaaacagat gaaggtaaaa aattactttt tgataatttt
     3481 aataaaaaaa tagattctat tgaaaaacaa ggtcaattta cagatagatt aagacaaatg
     3541 tatgctgatt tttgtacaga tggacttaca ataaagaaat atttattgat tggaagtatg
     3601 ctactttatt ttgttatatc aacagatgtg attccagact tcgtattccc aataggattt
     3661 atggatgatt tagtagcatt aaatatagtt acaaaattac ttaaaaatga taagtaagtt
     3721 ttagaatcat atttaatata taaataaatc aaagtatata aaatttatta ttttttatat
     3781 gaaacaaatt aaaagcacaa tgaagtagat taaaaattta aaactaagaa tctaatatat
     3841 attttgtaac tatttaagta tataaaataa aataatatcc aaactaatac aaaatagtaa
     3901 taattgtttt gtactggagg atatatattt atgaattgta aatggatatc taaaatagat
     3961 gagagaaaaa aatgtcatag agaagcagat tcttctggat attgtatctt tcataaagaa
     4021 aataagtctg atgaagaaat acagttgatg atggatacta ttcataaaga agagataagt
     4081 gaatttaatg gatttgtttt tgaaaatgaa tttaatgcgg aagaaatatt aacttacaat
     4141 tataaaatac tggatttttc tgaatccata tttaaacaaa aagcaaattt taaaaaatat
     4201 atttttaaaa agaatattat ttttaactat acagaattta gagataaagt tttatttaat
     4261 ggttgtgtat tcttagaaaa ctgtgatttt aatagaagca tatttagtaa aaactatata
     4321 aatgaccgta tatttgaaaa agtgaaattt aaaggacctg atttggtagt taataaagta
     4381 gaaaattttc caagaatgga tggaataatt tttagcatgt gtacaaaatt tgtgttaaag
     4441 aatgttgaat atggaaaaag tgagtatgag catggcaaga taaattatag aatagctaga
     4501 aatcaagcaa caaaaattgg agaatatgag atgataggat tttactatta taaggaaaga
     4561 atttatagta gtaaaataat gaaacgttct aattatccta ctttcagtga ttatttagtt
     4621 gaaaaatttt ttgaccaaat agcacgttac acaacaggtt atggagaaaa gccatggaat
     4681 atattattag ttattatagc aataataagt gtttttgctt tattatactt atttgtaggc
     4741 atagaaagtt caaatagcac acttgtagct ttagatataa ataatatagg tgattactca
     4801 ctaagtgaga ttttcaaaat gtatatggat ttatggtatt ttagcatggc tacatttagt
     4861 acagtaggat atggagatat ggttgctaca agtttgattg ggaaagcatt ggcaggtata
     4921 gaagtatttt ttggagttac aataggagca atttgggcat ctgtgattat taaaagaatg
     4981 ataaggtaat atttgtgtaa atatggatag gtattaatta ctagatataa attggactaa
     5041 atagggaaaa tttaaatata aatatactta ataatccaag aaggtgaaaa atttgaaaaa
     5101 tgcactaaaa aaaattatat cattagccat gattctagtt tttataatac caaattattc
     5161 atatgcagat gataaatctg tagacaagta ttcaaaaaca tctatactta tagaccaaga
     5221 aacaggtaga gttttatata gtaaagaacc tgatatgaag gtaccattag ctagtttaag
     5281 taagatgatg acttttttac ttgcaataga agctattgaa aataaagaag taaaagaaac
     5341 tgataaagta aaaatagaca aatctattgc atcagtaaaa gggtcaagtt ataaacttaa
     5401 agatggtgaa gaagtgccac ttatagagct tatgagaggt cttatgattg tatcaggaaa
     5461 tgatgcggca attgctatag caaaacatat ttgtaaaacg aaagaagcat ttgtagatag
     5521 aatgaataaa aaagcaaaag aaataggaat gagtaataca cattttctaa atccaaatgg
     5581 tcttccaata tacgatttaa gcaaccccaa aaaaccagca aaagaaaata tctctactgc
     5641 aaaagatata gctattcttg gaaaatacat gtttgaccat tatgaaaaac aagtaacagc
     5701 tataactgat atggagacat atacaaattc agatagaagt tttgaaaaaa gcaatacaaa
     5761 tgcattatta agaattatac cagaagtaga tggtataaaa actggatata ctggcaatgc
     5821 tggatattgc ttatcatttt ctatgattgt aaataaaaat gataaaaatg agaaaaaacg
     5881 tagagtaata ggggttgtat taggtactaa ccataaaaat aaaagaacct ctgcttcatt
     5941 agctctactg aaatatggaa aagaaaattt caatatgaaa aaagtaattg ataaagatag
     6001 ctttattggt aagaaatata taaaaggaat gaaagagtta gaggttacat taaaagcaaa
     6061 agatgaactt tatacaatat taaaagatga tgaaagtata aaatcagaag ttaagattaa
     6121 aaatatagag taccctgtta aaaaaggtga tactatgggt attataaaat attatactaa
     6181 ttcaggtgac ttacttggaa gtgtagatat agtaagtaat aatagtatag ataacgtatc
     6241 attaaaaaca aaattaaaaa tgaaatttgc aaattaaatt caaaaaatgg tataaaatac
     6301 acaaaaaaat ataaaaatag aaaatatgga aaaaatattg ttatttcttc acctctgtga
     6361 tatactacta gaggtgaaaa aataaaataa atcacacaca gcattgggat ccttaaaagg
     6421 tgcctattac atggtttttt agggagaaga tcaagctgga ggtataaaac caggaggtaa
     6481 gatatgtcag taatatcaat gaaacaatta ttagaagcag gtgttcactt tggtcaccaa
     6541 acaagaagat ggaaccctaa aatggctaag tatatattca cagagagaaa tggaatatat
     6601 ataatcgact tacaaaaaac agttaaaaaa gttgaagaag cttacaagtt cactaaagaa
     6661 gtagctgaaa caggaaagcc aatcttattc gtaggaacta aaaaacaagc tcaagatgcg
     6721 ataaaagatg aagctgaaag atgtggaatg tactttgtta atgaaagatg gttaggtgga
     6781 atgttaacaa accacaaaac tataaaaaca agaataaata aattaagaga attagaaaaa
     6841 atggaagaag aaggcgtatt taatgttctt cctaaaaaag aagttataaa attaagagct
     6901 gaaaaagaaa aactagaaaa atacttaggt ggaataaaag acatgcctga attaccaggt
     6961 gcaatgttcg tagttgaccc aagaaaagaa aacatagcta ttcaagaagc tcatagatta
     7021 ggtataccag tagttggtat agttgatact aactgtgacc cagaacaatt agactttgct
     7081 ataccaggaa atgatgacgc tataagagcc gtaaaattaa taactggtgc tatggcaaca
     7141 gctgtaattg aaggtagaca aggtgctgag gaagaagtag ctgaagacca agaataataa
     7201 tttgacaatt aaatggtaag ggtcgccctt accatttata atatggaata gaataagtag
     7261 gaggaaactt aaaaaatggc taatataact gctcaaatgg taaaagagtt aagagaaagt
     7321 acaggcgcag gaatgatgga ctgcaagaaa gctttacaag aagctgaagg aaacatggaa
     7381 aaagcagtag atttattaag agaaaaagga ttatcaaaag ctgctaaaaa agctggtaga
     7441 gttgctgctg aaggtctagt tgcaatagaa atgaatgatg ataatacagt tgcttctatg
     7501 gtagaagtta actcagagac agatttcgtt gctaaaaacg aagacttcaa agtgttcgtt
     7561 aaagatgctg cttgtatggc attagctact gataaagaag atatagcttc tttattaggt
     7621 gaaactcata aagagggaat aactttacaa gaagttttaa ataatagagt tgcaaaaata
     7681 ggtgagaaat tagactttag aagatttgct aaagttgtaa ctaatggaca agttgctgga
     7741 tacattcacg gtggtggaaa aataggtgtt cttgttgaaa tggaaacaga agctagagat
     7801 gctaaagttt tagaattagg taaagatgta gctatgcaag ttgctgctat gaatcctaag
     7861 tatgtttcaa gagatgaagt agatgctgaa tacatagcac atgaaacaga agtattaact
     7921 caacaagctt taaatgaagg aaaaccagct aatatagttg aaaaaatggt taaaggaaga
     7981 ttagaaaaag aattaaaaga ggtttgttta ttagagcaaa ctttcgttaa aaatccagat
     8041 ataactgtta aacaattagt tgctgatgtt gctaaggcag taggttctga tataaaagtt
     8101 gttaaagttg tgagattcga agttggtgaa ggtatacaaa agagagaaga aaactttgca
     8161 gaagaagttg ctaagcaact taagtaataa ccaaagagag aacacgcagg tgttctcttt
     8221 tttaaaaaat agaaaaaatt ggatatgaag gattgaaata ggaggtttct gatggataaa
     8281 ccaatgtaca aaagggtatt gttaaaatta agtggagaag cattagcagg agaaagaggt
     8341 tttggtataa ataatgatgt agttaatgat attgctattg ctataaaaaa aatacaagaa
     8401 ataggtgttg aagtagctgt agtagtaggt ggaggaaact tctggagagg cagaaccagt
     8461 gaaggaatgg acagaactac tgctgactat ataggaatgt tagctacagt tatgaatgca
     8521 atggcgctac aggatgcact agaaaatata gatgttgcta caagagttca aactgctata
     8581 gacatgagac aaattgcaga accatatata agaagaagag cagttagaca cttagaaaag
     8641 gaaagagttg ttatatttgg tgcaggaaca ggaaaccctt actttacaac agatacaact
     8701 gctgctttac gtgctgctga gatggaagca gaagttatat tgttagctaa aaatgttgat
     8761 gcagtatatg acaaggatcc aaaagtacat gcagatgcta agaaatttac agaattaagt
     8821 tacatggaag ttatacagaa agaattaaaa gtaatggatt ctacagctac atctttatgt
     8881 atggataata aaattccaat aaaggtattt gagcttacaa cagagaatat aataagagca
     8941 gtaaaaggcg aaaatatagg aactactgta aaataatgaa gaatgaagga ggagtaaaat
     9001 tatgaaactg gaaatacata agcaattaga agagaaaatg aatgggacaa ttgatgcttt
     9061 aaagtttgaa tttggaacta taagagcagg aagagctaat gcacaaatgc tagacaaaat
     9121 aagagttgat tattatggaa ctccaactcc aataaatcaa ataggtgcta tatctgtacc
     9181 agaaccaaga atattaatga tatctccttg ggataaatct gctatgcatg aaatagaaaa
     9241 agcgatagct aactcagact taggattaaa tccatcaaat gatggtgagg ttataagact
     9301 ttctgtacct gctttaacag aagaaagaag aaaagaatta gctaaaaaag ctagtaaagc
     9361 tgcagaagaa tttaaagtta gaataagaaa tgaaagaaga gacgccaatg agaaaattaa
     9421 aaagatggaa aaaggcggag aattaactga agatgaatta aaaaaagcac aagatgaagt
     9481 tcaaaaaatg actgataaat ttataaaaga aatagatgca ttattatcta aaaaagaaaa
     9541 ggacataatg gaggtataat attgaaaaaa tattataacc ttttaggtct tcatgtagat
     9601 gaggtaaaac aatattttga tgagcaaaat ataaattata ccgtaaaatc tattgaaggt
     9661 aaaaaggata aagaaaaact tgtagttcct agagttataa aaatatctga gataggtgat
     9721 agtgtagaac tgataatcac atacttttct gactccttag tttaaggagt cagaacaata
     9781 ttggaggcaa aatatgaata acaacattat atatgatata gacttaaata acatacctac
     9841 tcatattgct attataatgg atggaaatgg aagatgggca aaagctagat ttcttccaag
     9901 aactgcagga cataaggctg gagtagaaac tataagagat atagtaaaag aatgctcaaa
     9961 attaggtgtt aagcacttaa cattatatgc attttcaaca gaaaactgga aaagaccgaa
    10021 acttgaagtt gacacactta tgaacttatt atctacatac ttaagaaatg aaatagctga
    10081 acttcaccaa aacaatgtaa aagtaactgc tataggagat ataagtgctt taccaaaaac
    10141 ttgtataaga gaattaaact cagctaagga actgacaaaa aacaatacag gagttaactt
    10201 aaatttagca ttaaactacg gaagtagagc agatataaaa aatgctctta tagatatagt
    10261 aaaaaattgt gaaagtggta aaatagatat aaacaatatt gatgaagata ttataaaaaa
    10321 ctatttaagc acaaagtcta taccagatcc agacttggta ataagaacaa gtggtgaaca
    10381 aagattgagt aactttttac tttgggaagt tgcttattct gagttttact ttactgatat
    10441 acattggcct gattttaaaa aagaagaact acagaaggct atatacgtat atcaaagaag
    10501 ggatagaaga tttggaggac ttaagtaagg agattatttt atgcttacaa gaattattgc
    10561 ttcactagct ctggttccat tatttctatt tgttgtatat ggaggtattc ctctatatat
    10621 agctgagaca gcaatagttt atattgcatt gcatgagttt tataaggcat ttaaaataaa
    10681 agatgtacat ccaatattca ttataggata tttattttct atttatttag ctgtaaaaaa
    10741 tatttttaat ttaccattag aatatactta tgcagtaatt tttattttat ttttagcaag
    10801 tataatttat atgttgatgg gcaaaaacaa tgttatagat gtttcgatta cgtttttagg
    10861 agttttttat ataggagtat ttttagattt tataattata actataaatg gatttgaaaa
    10921 aggtagtata tatgtatggc ttatatttgt gatatctttt atgacagata tatttgcata
    10981 ttttagtggt tatttacttg gaaaacataa gctaattcct aaagttagtc ctaaaaagac
    11041 tatagaagga gctattggag gaataatagg aagtacactt tgttgtattt tatttggata
    11101 tttatttggc attgatttgc ttcaattagc gataatagga agtataggaa gtgtaatagc
    11161 tcaattagga gatttatttg catcttctat aaagagatat gtagggataa aggattatgg
    11221 aaagataata cctggtcatg ggggtatatt agatagattt gatagtgtta tattagttgc
    11281 accttttgta tatagtgcga ttaaattttt tattagataa agattggttg gatttaaaag
    11341 agcaatctat aattgctagt aatgaaaata gctatgtaac ttttaaatgc agagatattc
    11401 tgcagttatt agttacatgg ctattttcat tgttcaaaaa tttagaagac cttggggaat
    11461 tgtataagaa taggtattac tttataatag tatactatat ttgtagtgag tatatttttt
    11521 atactgtaac tatcattaaa aaatattttt ttgtttaata atttcgatat ttttagcttt
    11581 attatatatt tataatatat atgtataaat gtaactaatt tattatccat ttataaattt
    11641 tatttttaaa tataattaat aagaga
//
LOCUS       DAYAKB010000103        11391 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.104, whole genome shotgun sequence.
ACCESSION   DAYAKB010000103 DAYAKB010000000
VERSION     DAYAKB010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.104"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..852)
                     /locus_tag="ACGI3L_003309"
     CDS             complement(<1..852)
                     /locus_tag="ACGI3L_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9199004.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIV"
     gene            complement(1358..1579)
                     /locus_tag="ACGI3L_003310"
     CDS             complement(1358..1579)
                     /locus_tag="ACGI3L_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199005.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(2080..3060)
                     /locus_tag="ACGI3L_003311"
     CDS             complement(2080..3060)
                     /locus_tag="ACGI3L_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199006.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(3224..4096)
                     /locus_tag="ACGI3L_003312"
     CDS             complement(3224..4096)
                     /locus_tag="ACGI3L_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9199007.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANSKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(4260..4811)
                     /locus_tag="ACGI3L_003313"
     CDS             complement(4260..4811)
                     /locus_tag="ACGI3L_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199008.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(4831..5733)
                     /locus_tag="ACGI3L_003314"
     CDS             complement(4831..5733)
                     /locus_tag="ACGI3L_003314"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HFG9199009.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(5748..8120)
                     /locus_tag="ACGI3L_003315"
     CDS             complement(5748..8120)
                     /locus_tag="ACGI3L_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HFG9199010.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(8341..9030)
                     /locus_tag="ACGI3L_003316"
     CDS             complement(8341..9030)
                     /locus_tag="ACGI3L_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9199011.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(9271..10650)
                     /locus_tag="ACGI3L_003317"
     CDS             complement(9271..10650)
                     /locus_tag="ACGI3L_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9199012.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPYLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(10644..11357)
                     /gene="rgbR"
                     /locus_tag="ACGI3L_003318"
     CDS             complement(10644..11357)
                     /gene="rgbR"
                     /locus_tag="ACGI3L_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HFG9199013.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
BASE COUNT         3719 a         1969 c         1049 g         4654 t
ORIGIN      
        1 tactatctta tagtcttctg gcactttata atctttgtct ggagtaccta aattccattt
       61 taaatcaaac atagttgcac ttattattgt tgcaaaataa agcataacta taccaatgtc
      121 tattttttct tcatataaat tagtatgacc atcttttcta acagctaaaa ctacagtgcc
      181 tccatcaact ataaatctcc atggttgtct atttaatgta gatggagcta atcttgcata
      241 gtgaaatgca tcaagaagtg ctctttcttc taagatttct atacttgcaa catttcccca
      301 ttcgttcata taaacaacat cttctacacc tagtctagta gaccccttat ctgttacaac
      361 ttgcatatca gattttgaat aattttgccc agtttttgta gcatttaata ctttagcatt
      421 acttacattt tctccatatc caatagctat aattcctgtt acctctttat ctgaattaat
      481 tccaagtttt tcttttacct tttttccatc ttcaaaagta acccaacaag aaccaattcc
      541 aagttctgtt actttaaaga ttatactttc tcctatgtac cctgaatttt caatgtaatt
      601 atcttttatg tcagataata ttataatata acttggagaa tctatcatat ttcctttgta
      661 ccctgctact ttatctaaat tattaaaaac ttcacttcta ttcataattc ttacatcaac
      721 atctatttct ggaactagtt tcttacaaga ttctgagtat ttcttaattt cactaagata
      781 ttcttcttta atatctgtgt tcttatattc tctaacagac tttctattta atatgattgt
      841 tttataatcc ataattttat cctccccaaa ctagtattgt cttaattata tacccattaa
      901 tatattattt tactcattta tttaataaat aaagattaca attttgtaat tattatttat
      961 taataatatt ccacttttac attaataatg accagttgtg caaaatccat tgccaaccac
     1021 caaataaaaa catattataa aggtaatata aaataacaaa caaatcttaa caaaaaatta
     1081 aacttttttt acacgaaaga aggcttcccg ttgccttctt tatttttata aaaaaataag
     1141 ctgtttctaa aatgatttca catttttgaa acagccaagt tattctataa tgacaactat
     1201 aatttgagga tgtgagggag agttgtcatt ataaatttag ggtaattata ttatgtttta
     1261 agctagttct ttctatattt atataataca ttttatatat gaattttata tgagattggt
     1321 ataaatgata tatgaaatta catatgttta tattatatta aattttatta ttacattttc
     1381 cacaacaata ctcatatgtc tccacattat ttggaatatt tacaaataca aattctttac
     1441 agttctcaca atactttaat atagatatag ttccacaagt gtaacattca aatattacac
     1501 aatcctcatt ttcctctact atttcaaact ttttactatg ttcaccacac tctgggcact
     1561 tgtgattatt tacattcata aatactcctc cttattagta tagttacatg tcaaaaactt
     1621 aattaatgta ttctatatta cttattatat attctataat aaatcatatt ctaatataat
     1681 aaaacaaatt aaataaaaaa aaaccataaa ttttaaattt atggattaat tcttgtaatg
     1741 ataactctat ttgaggatgt gagggagggt tatcattaca atagggtatt atattatggt
     1801 ttttaagcta gtctttctac acctcatatg atacatatgc tatatgaatt ttatatgatt
     1861 tttacataaa tattttatga aatttaaatt ttttagtcat tttgaaattt gtaaaaagtt
     1921 ctctaaaaat ccacagcatc ataaacagcc aaaatttaag tagaacatca taaaaaaatt
     1981 tgtccaataa ttttaacaag taatctcacc tcattataat tattgacaca aacttaaata
     2041 aacaatctat aaatcttcta taaatcttaa actttccccc tattgataca caatttctag
     2101 tttgtcaatt ttattttgca tttctaagaa aatttcttca acagaattgt taaatatatt
     2161 gcctaaatag attcttttat ctttttgaaa tgaataagat tttacactac catcagaaga
     2221 aatatataaa tgactccact ctgctccata ttttgaaaac ctctcctttg tatctttaaa
     2281 cctcatatct tctattttta ttgctttttc tctgtctcct cttactacag tgtgacccct
     2341 ttttattaaa ctggttattt ttatatcttc ttttaattta atacgtgtat catcattttt
     2401 tgaatatact ttccatatca ctttatgacg ataattatct aattccttta ttaagcttct
     2461 atcaatagta aaactatctt tagttaccac aattaaatca aaatggtcta acatatattg
     2521 aaatatttct ctcatacttt tattttttaa aatatcctca ccaataacct ctataaatct
     2581 acagcctttc tcatacatgc agttcaataa acttgtgatt tcagaaaaat aatcatttgt
     2641 attattatct ccatctattt ctatagtaaa gtacaaagga gtaatgtatg atttatttcc
     2701 tgttatctca aatacacttg atagtgtctg tatatcatct tcaaacgtta agtatacatt
     2761 ctcataaaac ataaaaaatt ccataacttt ttctttcata ttatggatat ttctatatct
     2821 attggataat atatttatta tatcgtcagt agtatttttc ccatcacatt cagccagtat
     2881 aacaatttgc ttccaactta agctatccac atttccgata ctttttttat atccatcttc
     2941 ttcatcataa ataggaccaa ttataatgtt ttcttttggc cacagatgaa ccctagttcc
     3001 atcttttaat ttcggatatt tattttttac agactcataa aatctacttg tatcacccat
     3061 gattctttac taccccccat agtttaaata ttctatgcta aaaatagcac tttattttta
     3121 ttaattcaac aattattcaa aattggtcat tatatatgtt taaatggatt taacatcaac
     3181 cttatttata tgttattgat gtttatatat gttatataaa atcttatttc tcatacttca
     3241 atgtaatctt aactatctct ggtttacaat taagcctaat taaaactttt gagcctccta
     3301 agcctttatt taaaatcata gtgctattat ctttttcata ttttccccag tcatacttag
     3361 gaaagaactc tctatttgga gataatacac ctccaacaaa aggtattctt attatacctc
     3421 catgaacatg tcctgctaaa accaaatctg ctccccattt tgcatatttt tcaaagaaaa
     3481 atggtgtatg tgctaaaaga atgttatatt cattttcatt aactttacct agattgtctt
     3541 ctacaaaatt gtcacttagt tctaattttt tgctattagc aaataaatat ggatagcatt
     3601 ccaatggtat aattaaacca tataaattaa gatggctatt acctctatat attcttacag
     3661 attcattttc catatttatt attttctttg aatatagttc cttaaaataa tccttatata
     3721 gatgtttata cttttttatt aaagattttt gttcatgatt tccaattata tgatatactt
     3781 catatttttc aaccaaatta tctattaaat ctaatgcaac ttgaaaattt ttattttctc
     3841 catctactaa atctcctgtt ataaatataa catctgggtt taatgattca attttatcta
     3901 tcaatacctt attattttta tcaaacacct tattatgtaa atcactcact tgaactattt
     3961 taaagttatc aaattccttt ggaatttttt tgttgaaaat agtatattct gtcgtttcta
     4021 tatgctgagt ttcatactta tacagaatat acaataatat taatactaat actgtcattg
     4081 aaacctttat aatcatattc tcttcctctt tattctattt tgttaatatt attataatgc
     4141 ttttatgttt tttttaaaac aataacatca tcacatacat ataaatcttt tcgacattat
     4201 aaaaataagt tatccttttc taaaattttc atttatttta gaaaaggata actataaaat
     4261 tatctataaa cctctatatt gtgaaatata gtttttcctt tatttaaatt tttatatata
     4321 tgctctaaag ttccatcaaa cctaatagaa tgtccagact ctaaaatata agttttccca
     4381 tccacattaa ggtcaagttt accttctatt acgagtacat actcttctaa aacatgactg
     4441 tgtgtagatg aaacatgagt acagttttcc tcaagctcaa ttataaaaag ttcaaacctt
     4501 ctttgagggc taaaagggta tattggatat aacttcatgt tccctttttg ctcaacaata
     4561 ggctctactt cttctttctt tataacctca taggtatttg tattttcatt taatagtgta
     4621 gtaaaattta ttttaaatcc agatgaaatt ttccataaag tagatactgt cggacttgat
     4681 tcacctctct caatctgtcc aagcattgct ttactgacac ctgtcatctt tgaagctttg
     4741 tctaaactta tgcccatttc ttgtctcaat aaccttaaat tttctcccac attaggaaat
     4801 ttattatcca tgttaaaatc ctcctgatag ctatttgtat tctatgattt ttactcctgt
     4861 aagttctact atctctttta attttaacat atgattgtta caaatttcat caaattcata
     4921 tatataatct tcaagcccta atgccttata tttatcgatt ccaaatttat gatatggaag
     4981 taactccatc ttgcctcctg gaacattttg tttgacaaat aatgcagtat ttcttatatt
     5041 ttcttcacta tcatttactc cataaataat tggcactctt ataaccatag atttattcaa
     5101 ctttgaaagc ctacatatat tatctaatat aattttatta cttactcctg tatattcttt
     5161 atgaatatta tcatccatag attttatatc tacaaatatg tggtctattt tctcaaatac
     5221 atcatttacc ttattccaat caaaatatcc acaagtttca attgcaatat ttatgccttt
     5281 atcataaaaa atatcaacta attctcttaa aaaatcaatc tgaagtgtag gttcacctcc
     5341 agaaaaagtt atccctccat tagattcaaa gaaaaatata aaatcttttt caacttcctc
     5401 tactatttct tcaacactca tttcttcggt cattatacaa atggcatctt taagacatac
     5461 cttgatacac tctccacata aatcacattt attatttatt tgcgctctat caaatagtga
     5521 acttatattt tgaggacaaa catctataca tctattacag gatacacatt tatctttcat
     5581 aacacctaat tttactatgt tactccagga atctggatta gaacaccact tacattttaa
     5641 tttacatcct tctaaaaata tagtagtcct tattccatct ccatcattta ctgaaaaatg
     5701 ttgtactttt acaactctac cttttttact cataatctac ctcataatta aaaattgcta
     5761 tgtgaatttc tagctattat agcatcttgc atttctcttg ataaattaac aaattgagta
     5821 ctatatccag caactctcac taataaatct ttatattctt ctggattttc ttgagctttt
     5881 aatagagtat catttgatat cgtattaaat tgtacatgga atcctcctaa agcaaaatat
     5941 gatttaatca tagatgttag atttctaagt cctctttcag tttccaccaa atcttgattc
     6001 agtcttaaat ttagaagtgt tccaccagta tgaacatcat gatttatttt tgatgcagat
     6061 ttcattgctg ctagtggact tgttgtatca gtaccaacaa atggagaaac tccctctgtc
     6121 aaaggttttg tcgcttttct tccacaagga gttgcgccta cgatttttcc agttggtaca
     6181 tagtttgata tacccataaa tgcactatta aatttagagc caaaaatatc cttgtatttt
     6241 ctagtttcag tataataaaa atcagaaact tcaattgcta atgaatctac ataatcatta
     6301 tcatttccat acttaggaac atccaacgca agttttctta attcttcata accttcccaa
     6361 tcattattta gtgcttttgt taattcttct aacgtagtca ccttatcctc aaatactaat
     6421 ttttttatag ctgccaatga atttgaaact acacctaacc ctataccagt taatacagga
     6481 cctatattat attttgctcc tcctttactt aaatcaactc ccttatccaa acatccatct
     6541 acacaagtag ataaaaatgg tcttggtacc atttctttat gaatttgttg agcaacagta
     6601 gttcctataa cagaactttt tacaagatat gctaattgct ttaaaaactc atccttaagt
     6661 tcttcaaaag aagtaaattc tgtgatattt tttgtatcta accccatttt ttctccagtt
     6721 aatctactct taccttcatt catagcatat tctaaagctg ctgcaaaatt gatatttacg
     6781 gctgaagtcc actgtcctgt ttttctaaaa tgaggaacta cacaaccaca gttactccaa
     6841 tctctagcat cttctgcatc atatccatct tgtaataaca tttgtgcccc tgcactatcg
     6901 ctgtgtatag cagggaaacc agttccttgt tttaccaatt tagcaactgc cattacgaaa
     6961 ttgtctggtg ctccttgact cactctaaca cttaatcctg gttggtgagt ttttacactt
     7021 tctgtagcct ttaaacacat atatgagata tcattcgttc catcagtacc atttctcttt
     7081 ttaccaccaa cagtaagatt ttggaattga ttatatcctg caaagtaatt tgctgtattt
     7141 gctgatatag tccataccca ttctgataac ttaatccaaa gtgcttctat caattcttga
     7201 gcttctgatt cagttatttt accttctcta gcatcatttt cataatatgg atacatatat
     7261 tgatcaaatc tacctaaatt taatgccaat ggattttctg atagaatacc acctaattga
     7321 acaaaccata caaattgtat tgcttcataa aaattagttg gagggtttgc tggtacattc
     7381 atacatatct ctgaaatttt tataagttct aactttctct tttcatctgt ttcttgctta
     7441 ctcatctctt ttgcaagatt tgaatatctt tgtgccaatg tcataatacc ctgtgcaact
     7501 atagaaacag atttgtaaaa atctatcttt tcaatatttt ctgaaactga tatatctaat
     7561 tctttaattt ttttatctgc atcttcctta atccctttat atccttttac aaacaatata
     7621 tcttgataat ctggtgttac ttcaccaact gcctgtctcc acttagaatc attatctatt
     7681 attcctgtat ctactaatat cttagctgta tcttctggga ttcttgctaa gaaaacttct
     7741 tccaaagatt ttcccttcca atatggaaat atttcttttc ttataaattc tatttgttct
     7801 tttgatatta catatgggtc ttgagttctt ttatcaaaag tatccatttc tttgtctacc
     7861 cattgccaag aaaactctgg tgtcaatatc cctgttcttc taaattttcc tgctgtacct
     7921 actattaatt cattttcaaa gatttttata ggaagttctt tacatgtctc caaaaaagct
     7981 ttagctcttc ttatacagat agcttctccc tcagtttttt tatgtgattc tgtaaaaatt
     8041 ctagcccttt cacaacatat cataggttta gaattaatat attcttgtct aaatgcttct
     8101 attctattag tttgactcat ttaaaatccc cctttggata atatatacta catttttgta
     8161 tgttataaca tactttaatt atattatact gtcctttagc ataaaatgga agcaaaataa
     8221 cttatttttt ttcatctacc ttgaacacct atatattaat actttttttg ttaaatttat
     8281 aaaatctaaa aaaattttct atgatatatt ttctatattg ttatagttat gtctaatata
     8341 ctaatgattt gaaatatcaa atttgtatac tagacttagt tttaaaacct tagttgattg
     8401 tttaactttg ttaacttcaa catgtatatc cttcatataa ggaagctcta caacacctac
     8461 tcccttatta aagtcttctt caaccataga aaaaatttct ttctcagtta agttcgtatc
     8521 agtcaatgat ttaaataaat tgtatataaa tttaacatat ttatcactct cagataactt
     8581 atcatcttct ggatactctt tagcacagag aatatctatt gttacttttc cttctttatc
     8641 gtcttcagac atagaataga ataaacttcg aatatttttt tcaggtggtt tttcagcacc
     8701 atttatagat actacaaagc taccatctga ttttgagtta gtaatactat aaccactgtc
     8761 tattatagct ttcgaaaatc tttgagataa atcttttttt acttcttctc tacctttcgc
     8821 atcattaatc ttttgtgagt aattattaaa tagctcaata gattcatctt ttttatcttc
     8881 aacttgttct ttcaatgaat ctttactaat ttgttctgag ctacttaagt tcttatcaga
     8941 tacaggagac atacacccta ccatcaatgc taagctaaga tttaaagcca caattattgc
     9001 cactctattt atattccttt ttactttcat acacaatcct cccatcacac taaccgctct
     9061 aaagtattat tcattgcact agaatatatt tatattttct ttatattaaa gatttattat
     9121 tcaatacata tcaccttcct atccaattct tataacttac tattagtaaa attataagct
     9181 ccttaataca gaaataagga tgttatcttt tgttattaaa agataacatc cttatttttt
     9241 tgtatcaata catatgtccc aactggtaac ttaatcgccc caactgtcag tatcttggtc
     9301 caatggtata tatatattta gtataaattt atcgatacta ttttcaaata ataattctcc
     9361 attatatttt tgtaaagaag atttaatact ctgaatacct attccatgta cgaacttatc
     9421 cattttgttt gttaacaata tatttttatt aaaagtaagc tgatttagtt tactattttc
     9481 acatttaagt acaaaaaatg accttgttat agttccttta attctaatat atttattaat
     9541 attttcatcc actattttat cacatgcttc tattgcatta tccaaaatat tagaaaatat
     9601 gcttgacaca tctataggtt ttacaaaatt tacttttgaa aaatttatag agcaagtaaa
     9661 tttaattcct ttttttaaac atacttcact cttttcgttg attataatgt ctaatatcat
     9721 atttcctgta ttatagatat atttaaatgt ttttatttca tcttttaaat tgttaacata
     9781 ttcattaatt tctttgctat tgtttctaag gttgtctata caataaatgt gattatttat
     9841 atcgtgatat agtttcttaa ctcgcatatg agattcttga atacttaaat aatgcgcata
     9901 ttgcatatct aacttatttt ttattaattc agcttgagat tttaatctat tctcttttat
     9961 tatttcttta aacaatagta taagaaatat actactagct cctaccaatt ttggattaac
    10021 aaaattatca aaatagtatc cttctgaatg taatgaccca aaccgttcta atttttttaa
    10081 tacataattt acaagcatat tcattgtatt aactaataag gcaaataata aatatacata
    10141 atttctctta tcttggctaa ttaattttat agactttcta aaaaagctaa atataagata
    10201 tataagaata attattaaat tactatatat ctgaattttt atagattcta agtaaggtac
    10261 taataaagat tctttagatg aaataacatt acctgtaatt gcaaaaaata gtattctata
    10321 tataacagca tccaaacatt tataatatac actaaataga taaaagaaaa tggaatactt
    10381 aatataaccc atcttataaa aataattata gtatcctccc caagcaataa atgctaatat
    10441 ataaaataaa tagtttatat tactaaagta atttcctcca ttaaataatc tacttatctg
    10501 aattataata taaataagaa acaagacaat atagaatact attttttcat tttttttact
    10561 atccttttta taaattaaaa ttccgttcat tatagaaaac tgtataaata tagataaaac
    10621 tactaatagc tcagtcataa agtttagcat attgtatcac caagaaattt taagaatttc
    10681 tccttaactt ctttatatct atatctacta ataggtacct cttctccact ttccagtatt
    10741 gcagtattag gctttatatt ttcaacatat cttaaattta ctataaaact tttatggcat
    10801 cttataaatt tatatggatt taattctttt tctattttgc ctaaactata ttttatatca
    10861 aaattcttgt ttattgtgtg tattagcata tctttttttt gaacttctat atattttatt
    10921 tcatttaaat aaatcttata tgtattagac ttatttttta ttgtaatatg actttcctta
    10981 tttatttcaa tatctttgat acaagttagc acatgttttt ttagttcttc caactctatt
    11041 ggctttagta aatacctata agctcttacc tcataacctt cttgcacata atctattaat
    11101 gaagttacaa atattatttc catttcattg tctacttctc taatctttct tgcagtatcc
    11161 attccattta atttttccat ttttatatca agaagtaata tatctatatc ttttaaatta
    11221 ctttccagta actcttctcc agatatatac ttttgtatct catattctat acttatatct
    11281 tttaatatat tctcaaggta atcttctatt aaaagttgtg tttctttttc atcttcacaa
    11341 actgctatct taatcataaa atgcctcctt acataatttc tagttaatac a
//
LOCUS       DAYAKB010000104        11212 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.105, whole genome shotgun sequence.
ACCESSION   DAYAKB010000104 DAYAKB010000000
VERSION     DAYAKB010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11212
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.105"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1370
                     /locus_tag="ACGI3L_003319"
     CDS             <1..1370
                     /locus_tag="ACGI3L_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9199014.1"
                     /translation="TILNLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDI
                     FVDSLKVLLSEKEILDKVVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQN
                     LTKKLREKGQIAKYTFKDIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQ
                     SIHNNSNRKNQPFIAVNCAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTI
                     FLDEIGDMPLELQTKLLRVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFR
                     EDLYYRLNTIPINIPPLRERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIREL
                     QNVTSYLNIMCEDIVLEKDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDV
                     GIGRGLILKALLDKNLQITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKL
                     KYKGL"
     gene            1739..2959
                     /locus_tag="ACGI3L_003320"
     CDS             1739..2959
                     /locus_tag="ACGI3L_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9199015.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIEIKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            2996..4345
                     /locus_tag="ACGI3L_003321"
     CDS             2996..4345
                     /locus_tag="ACGI3L_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9199016.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKFFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            4459..5021
                     /locus_tag="ACGI3L_003322"
                     /pseudo
     CDS             4459..5021
                     /locus_tag="ACGI3L_003322"
                     /inference="COORDINATES: protein motif:HMM:NF037635.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5129..7462)
                     /locus_tag="ACGI3L_003323"
     CDS             complement(5129..7462)
                     /locus_tag="ACGI3L_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199017.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSRLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(7459..8142)
                     /locus_tag="ACGI3L_003324"
     CDS             complement(7459..8142)
                     /locus_tag="ACGI3L_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199018.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            complement(8213..9454)
                     /locus_tag="ACGI3L_003325"
     CDS             complement(8213..9454)
                     /locus_tag="ACGI3L_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9199019.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            complement(9465..10151)
                     /locus_tag="ACGI3L_003326"
     CDS             complement(9465..10151)
                     /locus_tag="ACGI3L_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199020.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
     gene            complement(10389..10733)
                     /locus_tag="ACGI3L_003327"
     CDS             complement(10389..10733)
                     /locus_tag="ACGI3L_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199021.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
BASE COUNT         4085 a         1618 c         1409 g         4100 t
ORIGIN      
        1 atacaatatt gaatttatca aaagatggta tattatttac ttcaaaagat ggtgaaataa
       61 atacatataa tagtaaagta aaagatattt tagacataaa tgaggatata tatggaaaat
      121 acattgagga tatatttgta gatagtttaa aagttttatt gagtgagaaa gagatactag
      181 ataaagttgt cgtattcaat aagaaatata taaatgtaaa taaaaaaaac atatacaata
      241 gagatgaaaa aatgggcaca tattatagtt tacaagaaat aacatacata aaaaaattag
      301 aacaaaatct cactaaaaaa ttaagagaaa aaggacaaat agcaaaatat acatttaagg
      361 atataaaaac aaatagtcct aaaatgtttg aatgtataga tttagctaag aaggtttcta
      421 aatctgactt aagcatactt atcagaggtg aaagtggaac tggtaaagaa ctcatagctc
      481 agtctataca taacaactca aatagaaaaa atcaaccctt tatagcagta aattgtgcag
      541 ccgttcctga aaatttatta gaaagccagc tattcggata tgacaaggga acttttactg
      601 gaggtctaaa agatggaaaa caaggattat ttgaacttgc taataatgga acaatattct
      661 tagatgaaat aggcgatatg cctttagaat tacaaacaaa actacttaga gttcttcaag
      721 aaaagcagat aatgcctgtt gggtctcaca atgtaattaa tatagatgtt agaatcatat
      781 ctgctacaaa taagaattta gaacaaatga ttgataatag ccaatttaga gaggatttat
      841 attatcgatt aaatacaatt ccaataaata tacctcctct aagagaaaga aaagaagaca
      901 tattaattat tatggaagat ttaattaata agaaattagt aatcacacca gaagcaaaaa
      961 aacttataca aaactatatg tggaaaggta atataagaga actccaaaat gttacatcct
     1021 atttaaacat tatgtgtgaa gatattgtat tagagaaaga tttacctcca aacttaaggt
     1081 cttcagataa caaaaataca tcattaaaac taaaatatag taagaatgat atattgaata
     1141 tattagagat actaatttta aataaggaat cagatgttgg tattggtaga ggattaattt
     1201 taaaagcact actcgataag aaccttcaaa ttacagaagg aaaaattaaa aaaatatttg
     1261 aatatctaaa aaaagaagaa cttataattt gtagttcagg aagatatgga agtaaaataa
     1321 ctcaaaaagg agaagatttt tacaataaat taaaatataa aggtctataa aattataatt
     1381 tatcaaacaa agaaatctat tcaggattaa agtactcctt caataggttt ttttattttt
     1441 caagtaccct gaaattataa tttattttgt acataaataa taggaattaa taggaatagg
     1501 ataatttttt tatttcctat tttttttata taaactagca tataaaatat attttcttca
     1561 aaataatatt ttttactgaa aattgaaact atgcaatcat tttttatact atacatatag
     1621 ataaatgatt atatttattc aatattctta taaaaaacaa agttctccat cgaaaattat
     1681 ggcataataa ttgcttatta tattaataaa acaataaaaa gcaattggag gaataaaaat
     1741 gcaacaggct ttgaaattaa aatatcaaac caaagaatta ggaaaagatt ttgtaataga
     1801 aagttgtaat tctataaaac catggcttat aaacataaga agagaattac ataaaattcc
     1861 agaattagct cttgaagaaa atcttactaa acagaaggta atttcttatt taaaagaaat
     1921 cggaattgat tatatggaat ttacaaaaca caatggaatt atggcatata ttttaaaaga
     1981 aagtgcagat aaaacgattt gtataagagc agatatggat gctcttccta ttgaagaaga
     2041 aaacaacata ccttataaat caatacattc tggaaaaatg catgcttgtg gccatgatgc
     2101 acatacaacc atgctacttg gagcatgtaa agttttacat tcaataaaag ataaacttaa
     2161 tgtaaatgta aaattcttat ttcaaccagc agaagaaggt tttggaggag caaaattctt
     2221 agttgaagat ggatgtttag aaaatcctaa ggtcgattat atattcggac ttcatgttat
     2281 gccacatatc gaaacaggat ttatcgaaat aaaatatgat acattaaatg ctagtgtaga
     2341 cactataaaa ataagtatca aaggtaaaag agctcatggt gcatatcctg aaaatggtat
     2401 tgatgcaata gttacagctt cacaaattgt tacatcatta caaactataa taagtagaaa
     2461 cttagaacca aataatgctg ctgttttgac tataggtaaa atatatggtg gtgatgcaca
     2521 caatgtaata tgtgaagatg taaaactaga aggcacttta agaaccttaa atagcaaaac
     2581 aagaaacttt atgattgata aaatagctaa aattgttgga gacactgcat ctgcatttgg
     2641 ttgtgttggg actttacatg taagtgatga aaactatcct gctgttataa atgaaaaaga
     2701 attagtagat acagttatat caaatactaa agaattactt ggagaggaaa aatttatatt
     2761 gagaccaaac ccgtctttag gtggtgaaga cttttctttt tacacagaac attgtaaagg
     2821 agcattcttc catttaggat gtaaaaatga ggaaaagggc ttaatttcac ctcttcatac
     2881 ctctagcttt aatatagatg aagattgttt accaataggt gttatgatgc atgtaatgaa
     2941 tactttgtat tttaattagt acagtaatta ataaaagaat aggagataaa ttaatatgga
     3001 aaaagctaag aaattaggtc tatttagtat gatattatta gggattaata gcataatagg
     3061 ttcaggtata ttcttactac caggtaaagt ttataatcta gcaggtcaaa acagtatgtt
     3121 tatatacatt tttgctacac tcttagttct atcaatactt ttatgttttg cagaagttgg
     3181 aagcatgttt gataagaatg gaggagcata tctatactcc aaaaaagctt ttggagattt
     3241 tataggattt gaagttggta caatgtcttg ggttattaga attatatcat ggtctactct
     3301 agcagtagga tttgcaacag ctttaggttc attttggcca gaatctgcca ctgaatacaa
     3361 aggttatata gctgcaatac tcgtaacact actttcaata aatagcttat ttggaattaa
     3421 aagcacaaag ataatgaata atgtaataac tatagctaaa ttagtaccat taatagtttt
     3481 tataatagtt ggaatattct ttataaaatt tgtaaatatt gttccttcag gaaatgtagt
     3541 taactctagt atgggtccag ccattatatt agtattttac gcatttaccg gctttgaatc
     3601 atttattgtg gcaagtggag aaatggaaaa tcctaaaaaa aatcttccag tcgcattaat
     3661 aaccacaata tttatatgtg caataattta tatattaatt caaattgtct gtatgggtat
     3721 acttggagat agactatttg aaaacagtat tccaattgca gatgcttcaa gtgtattttt
     3781 aggcaattat ggtaaatttt tcatatctgt agcaacatta atatctatat ttggtataaa
     3841 tataggttca tcaatagtaa ctcctaaatg tggttcttct ctagcagaag aaggttctct
     3901 tcctgcattt ataggaaaaa caaataaata tggtgctcca tatgtagcaa taataatatc
     3961 tttaatttgt tgtataccac ttgtgctaac tggaagtttt gaacaacttg cagtaatgag
     4021 tgtaattgca agatttgctc agtacatacc aacttgttta tcagtaatag ttttaagaaa
     4081 aagaacagat gttaaggcct cttttaagat tccatttggt cctgttatac caatggtagc
     4141 tattttaggt agcttatggt tgttacaaca agcttgggca gaagatattt caaaacctat
     4201 aactcaaaat agagttttaa taggattagg ggcaatgttg ttaatagctc ctctatatat
     4261 atttatgaaa aaaaataagg aaatcgagca taaaaataaa tcagaagatt ctaaattata
     4321 tatttcgaga gaaaaaattc aataatattt tacaaactat ttaaaaatta tttttctaat
     4381 actatagaaa taattagaaa tggagatgtt acgtatctaa aagtagttga taacacggat
     4441 attggtactt ttatagatat gggacttaca aaagacatac tagttccttt taaagctaag
     4501 acttatccat tgtttagaga tgaaaaatat ttattctata tatacttgga taaaagcgga
     4561 agaatagctg ctactacaga catagattca tatttagaaa cagaccatac ttacaatgta
     4621 ggagatgttg taaatggagt tgtatatgga ttccaaacca acaactctgc tatgatatgt
     4681 gttgacaata aatatgctgg tgtaatcctt cataatgaat actttacaga attaaaagct
     4741 ggggatgttc ttgaaaattt acatgttata aaaatatacg atgatggtaa attaggactt
     4801 tctcctagag gaaacagaaa agatgaactt gataccttag aaaataagat tttaagctat
     4861 ttagaaggtt cagatggata tatgagattc aatgataaat ctgatcctaa agatatttct
     4921 atcttattta attcaagtaa gaaaatttta aacgtgctct tggagtactt atgaagaaag
     4981 acttaattta tcaagatgaa gatggaactt atctaaagta aattatataa cacaaaaatc
     5041 gaagtaaatt atgaaagata ttttctattt catatttact tcgatttttt atttaaatta
     5101 ctacctctat ttaaattact acttatattt attgtgcatt tactacctct attatgtcta
     5161 attcacaaat ctttttaatt ggttttctta ctgcaagcaa agttattatt atcatagtta
     5221 ctacaatgat aaacagtaaa tcaaaaggta tttgccagtc tatatggaat tttaatgtta
     5281 ctaaggatac aaatatatat ctatgtaata ttaatccaag tacactcccc aataaacagc
     5341 cacttacagc atatgtactt gattctacta ttaccatttt tcttaattgc ttattggaca
     5401 tgcctattgc acgcataata ccatagtaat ttattctact tgtaacgctt atattcatac
     5461 tgtttatgat attaaacata cttataatcg caattataaa tacaaaccca tatacaaaaa
     5521 ctgccatagt gtaaaatgaa tttttagcct ctaagttacc ttgtcgctta tctcgaacct
     5581 ctaaattatc atctagaaca tttcttatat tttggattaa atcttcagga gcatcttcat
     5641 caacttgagt atcaattatt atatagtctt ttatatctgt tatactagta aaagtatttt
     5701 cagatgttat aatatttcca atatatttgt ctttaacatc aaatgaaatt gaagaaagta
     5761 tacctgctac ctctatctct ttcttagaat ttccattttt aatatatatc ttatctccaa
     5821 tattaaaccc atgaccttct tctaccaatc cgatattttc tgactctaat ttatcttcat
     5881 tgatttcccc ttttactaga tactttttgg cccagtcaaa ttgatttttt tcataagaaa
     5941 ttagctgaga tgttgcctcc ttattattgt atgtagcctc tacatccgtc atcattctac
     6001 tgtatacttt ttttattcct ttgatattac ttatttcatt aatatcgtct ttagtaagaa
     6061 cagacttaaa gtcagcgtca acaatagata tatgagcagc ttctggtttt ataggtttaa
     6121 gtgcctgata cataaagtct ataaatacac taaaacctaa aaacaataca atactaatag
     6181 caaatgaaga agtcataagt ataaaagatt tttttcttga aaaggcatga tttattccca
     6241 tagaaacatc aattttagaa cttcctgcgt tagcaatttt acttgctttt ccactagtta
     6301 aaatttcttt gaacattaga ttaccacgta tagcacttag tggagacacc ccagaagctt
     6361 tttttgctgg aacaatagct gataatatta ctgttaaaaa tcctactatt attccaaaca
     6421 caataccaat aaagctaacc tttaaaattg gcatcgaacc aaataactct gtattcacat
     6481 atttgagaaa tatagaggat ataatggtta caatacatcc taataacaat cctagtggaa
     6541 tagcctttac acttagaatt aaactttcta aaacaacaaa ttttttgact tggagttttg
     6601 atgctcccaa gcaacgtaat agtccaaaaa actttattct ctctattaca cccatattaa
     6661 agctattata tatcatgata atacttgcta ttaacacaag tataaaaagt cctcctgctg
     6721 ttaagtaaag tggtttagaa taatcagagt caccttgacc tataatagaa agtaattttt
     6781 catttttacc gatttgttta tcacttaaat tgaaggtatt cttaatatca gaagtagctt
     6841 ttctaatatt aaccttgtct ttaaatgtaa tataataata atcatatgtt tctgattttt
     6901 tgatagcttg tgtacctaat attgaaagca ttaatccatg cttatctgag gctcttaatc
     6961 ttgataatga tgaatattca cctactatct tataattttt atttctacca tctgctaatt
     7021 ttattttgat aaaatctcct acttttagat taaagctttt aactgcatct acatctatta
     7081 aagtctcatt ctccacaaca ggataacgac cttttattat ttctagacct aattgttttg
     7141 ctaaatcttc atctaaacct tgtatcaaaa tctcctttga tttaaactct ccattatcaa
     7201 tgacttgtcc tctaccatag tgagctatat ctactctact acttatttct gatatagctt
     7261 cttcattaag atttttaagt actatgtgcc aatttccatc atcttttata aattgtactt
     7321 tttgacattg tatagccatg tctgctagtc caaaaatagc agtaactaaa catactgcaa
     7381 tgacaataca taaaattgta gttctatttt ttttcttatg tacctttgca tattgtggta
     7441 ctagttctaa atagcttctc attctctatt cacccctagg tctttaagca ttccatcaga
     7501 aacctgtagt atcctatctg ctgtagaagc tatatttgta ttatgagtta tcataataat
     7561 agtttggtta tatttttctg ctgtcacttt taaaagtgaa attacatcac tgctattttt
     7621 actgtcaaga tttcctgttg gctcatctgc caatataatt gatggctttg taatcaatgc
     7681 tcttccaatt gcaacccttt gttgctgacc accagataat tgatttggaa gatgactttt
     7741 tctatcttta agacctaaaa ttgtcaatac ttcatctaga taaatagtgt ctggtttttt
     7801 gtaatctagt agtaaaggaa atattatatt ttgttccaca gttaattcgg gtataagatt
     7861 atatgattga aagataaaac ctatattacg acgtcgaaaa atagtctgtt tttcttcttt
     7921 cattgaacat atttctttac catcaacaaa tatttttcct gaggttggag tatcaagacc
     7981 tcctaaaaga tttaataatg tactcttacc tgagccagat tctccaacta cagtaacaaa
     8041 ctctcccttt gaaactgtaa atgatacatc ttttaatgcc tctacttttg tatatccatt
     8101 tccatatgtt ttacataaat tattaaccac aagaatatcc atttgctcta tctcctttct
     8161 gatgattaat ataagaataa ttcatacacc ttactgtaag atgtatccta tcttacatat
     8221 tagtaagctt taaaaaactt agagtaaatg tacttccttg taaaaaatta ctttctacag
     8281 ttatggttcc attgtgctgt tctatgatag atttaactag tggcaaccct aatccaaggc
     8341 cttgattact ttttgaaaac ttactcctat aaaatctttt aaatatatga tgtatatctt
     8401 caatatgaat tccatttccg gtatcactca ctgaaataat agttgttata ggtgtttcaa
     8461 cccattctat cattatttta tcgttctctt ttgtattatc taatgcattt tttataaggt
     8521 tgcttaaagc ttctgatatc cattcataat cgcaaaacaa gtttgtattt tctagacctc
     8581 ttatagagat actctttcct tctttttctg ctctagtttc aaaactatat aaaattttag
     8641 taatcaactt ttttacgtta acactagctt tgttaagaat tattgtcttt gaatctatct
     8701 ttgtaatctt taacaagttt tgtatcaatg attctatacg ctctaattca ttttgactct
     8761 tctgcacaaa attctcaaca atttcactat tatgactctc ttcctgcaat atttgattat
     8821 acatcatcaa tgctgtaagt ggagttttta gttgatgtga tatatctgaa attgtatttt
     8881 taagaaattc tttattctgc ttttctttca atatatgtgt gtttagagat gttgacatag
     8941 catctattga accaaataac tttgataaac taccttcttc ataagtattt aaccgtacat
     9001 ttatatttcc attcataaat gaatcaattt tataactagc ttcttctatc ttgttctgtt
     9061 gcctaaaaaa atacacatac aatataaaaa taatcatagt aaagaacaca aataaataca
     9121 aaaacatagt ttttatatat ttaccttgaa acaatttcac acttggcata aaactatcat
     9181 ctgtaccaaa gtcatatcta gctgtattta agatttcttt tccttttaaa gtatatttat
     9241 cttcattagt agtaaatact gctggtattt ttgatttatc aacacccata ctatttaagt
     9301 atccagctat attataatca tgttctaaca gtgcactttt ataatcatta gttatattta
     9361 taactactat ttgacctact actataaaca tcaataaaac ggatataatc accaaaaaaa
     9421 atatttttat gtctttatta gaaaatacct tcatattaac accctcactt tataacattc
     9481 catttgtaac ccattcttct aactgttaat agattttttg gattttcagg attatcttca
     9541 atcttatttc ttaaccttct tacatatact gacagagtat tatcatctac aaaactacca
     9601 tttccatccc ataacttatc caatatattt tttcttgtaa gtacaatatt tttatttttc
     9661 ataagtaagc ataataattt atattctgct gtagtaagtt caagctcaat ttcattttta
     9721 aaaacacgat tttcaagtaa tttaacagta atattatttg attttagttc agttacattt
     9781 tcacttgtaa aattataacg tctaagtaaa gcttttattc ttgaaattaa ctcatttaat
     9841 ttaaaaggtt ttgttatgta atcatctcca cccatatcaa gtcccatcac tacatttact
     9901 tcttcatcag aagcagttaa aaatatgatt ggtacattag aagcttctct taccctttta
     9961 caaatatcaa aaccatcacc atcaggtaag gatacatcca aaagcagtaa atcataattt
    10021 ttttctttat aaatttgcaa tgcttcttct actgttcttg ctacatcaac actaaatcca
    10081 ttcttttgta tagaatattc taatccatat atcaaactta aatcatcttc aaccaacaat
    10141 atactactca tctcaatcac ttccattttt ttatttttta ctttatatat attatatacc
    10201 taacttatta tatttttact cttttaaaaa tacaatacct tgaaatcaat gatttaaata
    10261 ttttaaaatt atttttatat gattttatat agttaattta atactttgaa atcttaataa
    10321 taaaaaaagc ttaaaataca ctaagtattc taagctttat tcaatcacat tttatatatt
    10381 tatattattt atttttttaa aatactattt tcaatattgc ctctattaaa catttcatta
    10441 tcattatcta aagagatatc acttatattt ctaacagttg ttgaatagtt accactaagt
    10501 tctatctcac tgaaatgcat atgcactatc ttttgtatta caaatcccat tgatgcaagt
    10561 aaaatagcaa atattatata ctgactaaag ttactcatat aataatttat aatggtatat
    10621 tcatttcctt tgactgttaa atgttttgta gatagcatag tatatatata ttcagtacaa
    10681 tttataaata catatatacc ataaatagct aacactacag ataaacaata cattgtgatt
    10741 gaaatctttg atattttttt aaacttacta tctttacaac acttaatatt tgttatttat
    10801 cataaacaag gttattgtat tatcaataat ttttaggtta cacttattat tagtcttgtg
    10861 ttaaaacgac agtagactta agagtagagt tttattaagc caatatttat atttgctata
    10921 cattgtaccc ctattacatc atacatataa cttggataac ttattttatt tttatttcta
    10981 aattatttaa aatcaatatc tacaccatta tcgataattg caattaaatt catataaaac
    11041 ctctttaatt tataggctgt tcactataaa gtctttattt cttccataaa attttcattt
    11101 tgaattttat tcaatgtttt tagtgtagtt atcatgatta tagatactaa aataaatact
    11161 attagtataa tagcccctat aaatttccaa tttattaaat tgatactttc aa
//
LOCUS       DAYAKB010000105        10985 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.106, whole genome shotgun sequence.
ACCESSION   DAYAKB010000105 DAYAKB010000000
VERSION     DAYAKB010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10985
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.106"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            248..3964
                     /gene="rpoB"
                     /locus_tag="ACGI3L_003328"
     CDS             248..3964
                     /gene="rpoB"
                     /locus_tag="ACGI3L_003328"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFG9199022.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            4006..7491
                     /gene="rpoC"
                     /locus_tag="ACGI3L_003329"
     CDS             4006..7491
                     /gene="rpoC"
                     /locus_tag="ACGI3L_003329"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFG9199023.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            7780..8202
                     /gene="rpsL"
                     /locus_tag="ACGI3L_003330"
     CDS             7780..8202
                     /gene="rpsL"
                     /locus_tag="ACGI3L_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFG9199024.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            8326..8796
                     /gene="rpsG"
                     /locus_tag="ACGI3L_003331"
     CDS             8326..8796
                     /gene="rpsG"
                     /locus_tag="ACGI3L_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFG9199025.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            8845..10911
                     /gene="fusA"
                     /locus_tag="ACGI3L_003332"
     CDS             8845..10911
                     /gene="fusA"
                     /locus_tag="ACGI3L_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFG9199026.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         4251 a         1404 c         2296 g         3034 t
ORIGIN      
        1 gatggtactt gtataaaatt ttttatagaa aattagacct ataaatgaaa aatatggatt
       61 ttatattgga aaattgtaca taatacataa tatatgctta aaataattta caaaaaatca
      121 aaaataatgc atagtttaca tataagataa aaaatatatt gaaaaatact tgacattatg
      181 ctaaaattat tagatgcgtt agaatgaact attgttttat ttttaattat tgagaggtga
      241 aaagtgaatg ccacatcctg tcacgatagg taaaagaact agaatgagct tttctaaaat
      301 taaggaaata gctgatgtgc caaatcttat agaaattcaa gtagattcct atgagtggtt
      361 tttaaaagaa ggtttaaaag aagtgtttga tgatatttca ccaatagaag attatactgg
      421 taatcttata ttggaatttg tcgactattc tctagatgat aaaccaaagt acgatataga
      481 agagtgtaaa gagagagatg ctacatattg tgcacctcta aaggttaagg taagacttat
      541 aaataaagaa acaggtgaga taaaagaaca agaagtgttt atgggtgact tccctttaat
      601 gacagaaaga ggaactttcg ttataaatgg agcagaaaga gttatagtaa gtcaattagt
      661 tagatctcct ggtgtttact atgcggaaga aagagataaa acaggtaaga gattgatttc
      721 atctactgta attcctaata gaggagcatg gttagaatat gaaacagatt ctaatgatgt
      781 aatatctgta agagttgata gaacaagaaa acaaccagtt acagttttac ttagagcttt
      841 aggaatagga acagatgcag agataattga ccttttagga gaagatgaga gattatctgc
      901 tacattagaa aaagataata ctaagacagt agaagaaggt cttgtagaga tatacaaaaa
      961 attaagacca ggtgaacctc ctactgtaga aagtgcatca tctttattaa atgctttatt
     1021 ctttgaccca aaaagatatg acctagcaaa agttggtaga tataaattca ataagaaact
     1081 tgctttatgt tatagaataa tgaataaaat ttcagcagaa gacataataa atccagaaac
     1141 tggagaagta tttgtaaaag ctggagaaaa aataagctat gatttggcta aagccataca
     1201 aaatgcaggt ataaatgtag taaatctact aatggatgat gataaaaaag ttagagttat
     1261 aggaaataat tttgtggata ttaagtctca cattgatttt gacatagatg atttaaacat
     1321 aaaagaaaaa gtacattatc caactttaaa agaaatttta gatggatata gtgatgaaga
     1381 agaaataaaa gaggctataa aatcaagaat taaagaactt ataccaaaac atatattatt
     1441 agatgatata atagcttcaa taagttatga gttcaatata ttctataata taggaaatat
     1501 tgatgatata gatcacctag gaaacagaag aataagatct gtaggtgaat tgttacaaaa
     1561 tcaagttaga attggtcttt caagaatgga aagagttata aaagaaagaa tgacggttca
     1621 agatatggaa gctataacgc ctcaagcgtt agttaacata agaccagttt cagctgcaat
     1681 aaaagaattt tttggtagtt ctcagttatc tcagttcatg gatcaaacaa atcctctatc
     1741 tgagttaacg cataagagaa gattatcagc ccttgggcct ggaggtcttt caagagaaag
     1801 agctggattc gaagtgcgtg acgttcacca ttcacactat ggtagaatgt gtccaataga
     1861 gactccagag ggaccaaata tcggtcttat aaactctcta ggaacttatg caaaaataaa
     1921 tgaatttgga tttatagaat caccatatag aaaatttgat aaagaaacat caacagttac
     1981 tgatgaaata cattatttaa ctgctgacga agaagattta ttcgtaagag ctcaggcaaa
     2041 tgagccatta acagaagatg gtaaattcgt aaaccataga gttgtttgta gaactgtaaa
     2101 tggtgctgtt gaaatggttc ctgaaagtag agtagattac atggatatat ctcctaagca
     2161 ggttgtatct gttgccactg ctatgatacc tttcttagaa aatgatgatg ccaaccgtgc
     2221 ccttatggga gcgaacatgc agcgtcaggc agtgcctcta gttagaagag aagcaccaat
     2281 tataggaact ggtatagaat acagagcagc aaaagactct ggagcagttg ttgttgctag
     2341 aaattctggt atagcagaaa gagtaacagc agatgaaata attataaaaa gagaagatgg
     2401 aaacagagat agatataatc tacttaagtt taaacgttca aactcaggta cttgtataaa
     2461 tcaaacacct ataataaata agggtgacca gataataaaa ggtgatgtta tagcagatgg
     2521 tccagcaact gatttaggag aagttgcact tggaagaaac tgtcttatag cattcatgac
     2581 ttgggaaggt tataactacg aggatgctat attaataaat gaaagattag ttaaagaaga
     2641 tagattatca acaattcata tagaagaata tgaatgtgaa gctagagata caaaactagg
     2701 gccagaggaa ataactagag atatacctaa tgttggagat agtgcaatta agaacttaga
     2761 tgacagaggt ataataagaa taggtgcaga agtagactca ggtgatatat tagttggtaa
     2821 agtaactcca aaaggagaaa ctgaacttac tgctgaggaa agattacttc gtgcaatatt
     2881 tggagaaaag gctagagaag ttagagatac ttcacttaaa gtgcctcatg gtgaatctgg
     2941 tataatagtt gatgtaaaag tatttactag agaaaatgga gatgatttat ctccaggagt
     3001 aaatgaatta gtaagatgct atatagctaa aaagagaaaa ataaaagttg gagataaaat
     3061 ggctggtcgt catggtaata aaggggttat ctcaagagta ttacctgaag aagatatgcc
     3121 attcatggaa aatggaacac cactagacat aatacttaac ccacaaggta taccatcacg
     3181 tatgaacatt ggtcaggttt tagaagttca tttaggactt gctgctaaga cattaggatg
     3241 gtatgtagca acatcagtat tcgatggtgc taatgagtat gacataatgg atgctcttga
     3301 agaagctggg tatcctagag atggtaaatt aactttatat gatggtagaa caggtgagtc
     3361 ttttgacaac agaataactg ttggatatat gtactacttg aaactacatc acttagtaga
     3421 tgaaaaacta catgcaagaa gtactggacc atactcatta gttactcaac agccactagg
     3481 tggtaaagca caatttggtg gacaaagatt tggagagatg gaggtttggg ctctggaagc
     3541 atatggagct gctcacatac ttcaagaaat acttactgtt aagtctgatg acgttgtagg
     3601 tcgtgttaga acatatgaag ctatagttaa aggtgaaaat atacctgaac caggaatccc
     3661 agaatcattt aaggttctta taaaagaact tcaaagttta tgcttagatg taaaagtatt
     3721 gacagatgaa gaccaagaaa tagaagtaag agaatctgtg gatgaagatg atacaatagg
     3781 tgaatttgag ctagatgttg taaatcatat gggagaagtt gaagaaagta atataataga
     3841 agaaattgaa gatgattttg cagaaaatgc agaagatgag gatatagaga atttagaaga
     3901 attcactgaa gatgatttat ttgaagaaga aatagatttt gatagtgatg actttgatat
     3961 gtaaatttaa ttaatgtaaa tctcaaatag aagggagaga actccttgtt tgaattaaac
     4021 aatttcgagt cgataaaaat agcattggct tctccagaaa aaataagaca atggtctagg
     4081 ggagaagtta aaaagccaga aactataaat taccgtactt taaaaccaga aaaagatggt
     4141 cttttctgtg aaagaatatt tggaccacaa aaagactggg agtgccactg tggtaaatat
     4201 agaagagtta gatataaagg tgtagtttgt gatagatgtg gagtagaagt aactaaatca
     4261 aaagtaagaa gagagagaat gggacatata gagctagctg ctcctatgtc tcacatctgg
     4321 tacttcaaag gtataccaag tagaatggga cttttacttg atatgtcacc aagatcgtta
     4381 gaaaaaatat tatactttgc ctcatatgtg gtagttgatc caggagagac tggattaaac
     4441 gaaaaacaat tgcttacaga aaaagaatac agaactgctc ttgaaaagta tggatatact
     4501 tttactgtag gaatgggtgc tgaagctgta aaaacattac tacaaaatat agatttagag
     4561 caacaaagta aagacctaag agcggagtta aaagatagta cagggcaaaa gaaagttaga
     4621 acaataagaa gattagaagt tgtagaggca tttaaaaagt ctggaaataa accagaatgg
     4681 atgattttag atgcaatacc agtaatacca ccagatttaa gaccaatggt acaacttgat
     4741 ggtggaagat ttgcgacttc agacctaaat gatttatata gaagagttat aaatagaaac
     4801 aacagactta aaagattatt agagcttgga gctccagata taattgtaag aaatgaaaaa
     4861 agaatgcttc aagaagctgt tgatgcattg atagataatg gtagaagagg tagacctgta
     4921 acaggacctg gaaatagacc acttaaatct ttatcagata tgttaaaagg taagcaaggt
     4981 cgtttccgtc aaaacttact tggtaagcgt gttgactact caggacgttc tgttatagtt
     5041 gttggaccag aacttaaatt ttatcaatgt ggacttccaa agaagatggc attagaatta
     5101 ttcaagccat ttgttatgga taaattagtt aaagaaggtt atgcacataa tataaaaagt
     5161 gcgaaatcta tagtagaaaa agttaagcca gaagtttggg atgttttaga agatgttata
     5221 aaaagtcatc cagttcttct taaccgtgca ccgactctac atagattagg tatacaagca
     5281 tttgaaccaa tcttagttga aggtaaggct ataaaactac atcctcttgt atgtacagct
     5341 tataatgcag actttgatgg tgaccaaatg gcagttcatg tacctttatc agtagaagca
     5401 caagcagaag caagattctt aatgctttct gtaaataata tacttgctcc taaagatggt
     5461 tcacctataa ctactccatc tcaggatatg gttttaggtt gctattatct aacaatagaa
     5521 gcccaagatg gagctaaagg aacaggtatg gtatttaaag actttaatga actattactt
     5581 gcttattaca ataaatcagt tcatctacat gcattagtga aacttaaggt aacacttgaa
     5641 gatggaagaa gttcattggt tgaaagtact gttggtagat ttatatttaa tgaaaatata
     5701 cctcaagact taggttttgt agatagaaaa gaaaatccat ttgcacttga agttgatttc
     5761 ttagcagata aaaaatctct tggtaaaata atagataaat gctttagaaa acacggaaat
     5821 acagaaacag ctgaattact agattatata aaagctctag gatttaaata ttctacatta
     5881 ggtggcataa cagttgctgt tgatgatatg agtgtcccag aagaaaagaa agtatttata
     5941 gctgaggcag aagctaaagt tgataagtat gaaaaagcat acagaagagg tctaatctct
     6001 gatgaagaaa gatatgaaaa agttatagag acatggacag aaacaactga taaagttact
     6061 gatgctctta tgggtggact agatagatta aataatatat atataatggc acattcagga
     6121 gccagaggtt ctaaaaacca aattagacag ctggcaggta tgcgtggtct tatggcaaat
     6181 gcatctggta aaacagttga gataccagtt aaatctaatt tccgtgaagg tttatcagta
     6241 ctagaatact ttacatcttc acatggtgcc agaaaaggtc ttgccgatac agctatacgt
     6301 acagctgaat ctggatattt aacaagaaga cttgttgatg taagtcaaga tgttattgta
     6361 agggaaatag attgtggaac agaagatact acagagattt atgctataaa agaaggaaat
     6421 gaagttatag aagagatata tgatagaatt gtaggaagat atactataga ccctatatta
     6481 aatcctgaaa ctggagaagt tatagttgag gctgattcaa tgatacaaga agatgaagca
     6541 gaaactatag tagctttagg aattgaaaaa attaggataa gaacagttct taactgtaaa
     6601 actaatcatg gagtttgttc taagtgttat ggtagaaact tggcaacagg aaaagaagtt
     6661 aatataggtg aagcagttgg tataatagca gctcaatcta tcggtgagcc gggtactcag
     6721 cttacaatgc gtacattcca tactggagga gttgcaggag ctgatataac tcaaggtcta
     6781 ccaagggttg aagaattatt tgaagctaga aaaccaaaag gattagctgt aataactgaa
     6841 gtatctggta gagttgaaat tgatgaaaca ggaaagagaa aagaagtaaa tgtaatacca
     6901 gaagaaggcg agactcaaac atatgtaatt ccatatggtt ctagattaaa agttaagcaa
     6961 ggtcaaatgc tagaggctgg agaccctcta acacaaggat ttataaatcc tcatgatata
     7021 gtaagagtaa atggtgttaa gggagttcaa gaatatatag ttaaagaagt tcaaagagtg
     7081 tatagacttc aaggggttga tgttaatgat aagcatatag aagttatagt aagacaaatg
     7141 ctatctaaag taaaagttga agacccagga gatacagatt tattgccagg tggatatgaa
     7201 gatgtattaa cattcaatga atgtaataaa gatgctatag ataaaggtct aagaccagca
     7261 gttgctaaaa gagttttact tggtataact aaagcatctc ttgcaactga ttcattctta
     7321 tcagcagctt ctttccaaga aacaacaaga gtattaacag aggcagcaat aaaaggtaaa
     7381 gaagaccact taataggact taaagaaaat gttatattag gtaagttaat accagcagga
     7441 acaggaatga agaaatatag aaatatagct gttgaaaaaa ttgaagatta atagcatata
     7501 gagtaaagaa atcttgacaa ccattatttg tggtgttaaa atagtaaagt gtgttgttta
     7561 aaagtacact aagggcttga acaagttctt agtgactttt agatggcaat aaatgagaac
     7621 taaaaagcat caagctagaa aagtgctaat atcacatatt tatgtgttat agacattaaa
     7681 ttgtaagtaa cgaatgttac aatcagtcag tatgaatatt catattgatg tagttggcgg
     7741 tcactgataa gatcgaaaat ttggaaggag gtgcagatga tgccaacaat taaccaatta
     7801 gttcgtaaaa gtagaaaagc gctagagaag aaatctactg ctccagcatt acaaaaaggt
     7861 tacaactctt taaataagaa agtaactgac gctagtgccc cacaaaaaag aggggtttgt
     7921 acttcagtaa aaacagttac tcctaagaag cctaactcag ctttaagaaa agttgccaga
     7981 gttagattaa ctaatggtat agaagtttct gcttatatac caggagaagg acacaactta
     8041 caagagcata gtgttgttct tataagagga ggaagagtaa aagaccttcc aggggttaga
     8101 taccatatac taagaggtac tctagataca gcaggtgttg ataagagaag acaatcaaga
     8161 tctaaatacg gtgcgaagag acctaaagaa gctaaaaagt aaaaacaatt aatgattgat
     8221 tatagttcgg tgctttaaat atatatatat ttacggcatc acggcattaa atgatttatg
     8281 tcgagtacct atgatttaag ttaaataatt aaggagggaa gcgaaatgcc aagaaaaggt
     8341 aatattccaa aaagagaagt tttaccagat cctatgtatg ggagtaaggt agttactaaa
     8401 ttaataaata atctaatggt agacggaaaa aaaggaaagt ctcaaagaat agtttatgat
     8461 gctttcgcaa ttgttgctga aaagacagga gaagaagctt tagaagtatt taataaagca
     8521 atggataata taatgcctgt tttagaagta aaagcaagaa gagttggtgg ggcaaactac
     8581 caagtgccaa tcgaagttag acctgaaaga agacaaacat taggtttaag atggctagta
     8641 aaatatacta gagctcgtgg agaaaaagga atggttgaaa agctagctaa agagataatg
     8701 gacgcagcta acaacactgg agcttcagtt aagaaaaaag aagatactca taaaatggca
     8761 gaagctaata aagcatttgc tcattacaga tggtaggata tatagatatc ttataaaatt
     8821 gaggatatca taaggaggat aaccatggct agaaagtttc ctttggaaag aactaggaat
     8881 ataggaatca tggctcatat agatgcagga aaaactacta ctacagaaag aatcctgttt
     8941 tatactgggc aaactcataa aataggagaa actcatgaag gagcttctca aatggactgg
     9001 atggagcaag aaaaggaaag aggtataaca ataacttctg ccgctactac tgcttcatgg
     9061 aaagaccata gaataaacat aatagatact cctggacacg tggacttcac agttgaggtt
     9121 gaaagatctc taagagttct tgacggttca gttgctgtat tctgtgcaaa aggtggggtt
     9181 gagcctcaat cagaaaatgt atggagacaa gctgaaactt atggagtacc tagaatagct
     9241 tttgtaaata aaatggatat attaggtgca gatttctaca atgttgtaag catgatgaaa
     9301 tctagattaa attctaatgc agttcctatg caattaccaa taggtaaaga agattcattt
     9361 ataggtataa tagacttatt aaaaatggat gctgttatat acaaagacga cctaggggtt
     9421 gaaatggaag aaacagatat accagaagat atgaaagaat tagctgctga gtggagagaa
     9481 aaattagttg aatcagtagc tgaaactgat gaagaattaa tgatgaaata ccttgaaggt
     9541 gaagaactta ctatagatga attaaaagtt gctataagaa aagctactat agcttgtgaa
     9601 atgaacccag ttttctgtgg tacagcttat agaaacaaag gtgttcagtt agtaatagat
     9661 gcagttttag attacttacc agcgccaact gatataccag ctataaaagg tatattagca
     9721 gatggagaag aagctgaaag acattcttct gatgaagagc cattctctgc attagcattc
     9781 aaaataatga ctgacccatt cgttggaaaa ctagcgttct tcagagttta ttctggaaca
     9841 ttagaatcag gttcttatgt tttaaatgca actaagaata agagagaaag aattggtcgt
     9901 atattacaaa tgcatgctaa tacaagagaa gaaataacta aagtgtatgc tggagatata
     9961 gcagcagcag taggattaaa agatactact actggagaca cattatgtga ccctgctaat
    10021 ccaataatac ttgaatctat ggaattccct gagccagtta tatctgttgc tatagaacca
    10081 agttctaaag cagctcaaga aaaaatgggt atagctcttc aaaaattagc tgaagaagac
    10141 ccaactttca cagttaagac tgaccaagaa acaggacaaa ctataatatc tggtatgggt
    10201 gaattacact tagagataat agtagataga ttattaagag aatttaaagt agaagctaaa
    10261 gttggtgcac cacaagttgc atatagagag actataactc aaccagttga tgttgaatac
    10321 aagtactcta agcaatcagg tggtagagga caatacggtc acgttaagat tagagttgct
    10381 cctcaagagc caggtgaagg atacaaattc acaaacaaaa ctgttggtgg atcagtacca
    10441 aaagaatatg ttggtccagt tgacatgggt atacaaggag ctatgcaatc tggtatagtt
    10501 gctggatatc cagttgtaga cgttgctgtt gagttatatg atggttctta ccatgaggtt
    10561 gactcttctg agatggcgtt taagatggct ggttcaatgg cattcaaaga tgctatgaag
    10621 aaaggtaatg cagttctttt agagccttac ttcaaagtag aagttgttac tccagaagat
    10681 tacatgggag atgttatggg tgacttaaac tcaagaagag gattaatcca aggtatggaa
    10741 gctagaagtg gtgcacaagt tataaatgca ttcgttccac tttcagaaat gtttggatac
    10801 tcaacagacc taagatcttc aactcaaggt cgtgcaactt acacaatgat attcgatcac
    10861 tatgagcaag ttccagcttc agttgctaag aaaatagctg aaggaaaata atttaaaaat
    10921 aattaataat ataaatataa aaaataatca gctagatgag agatatctct catctagcac
    10981 aagat
//
LOCUS       DAYAKB010000106        10642 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.107, whole genome shotgun sequence.
ACCESSION   DAYAKB010000106 DAYAKB010000000
VERSION     DAYAKB010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10642
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.107"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..321
                     /locus_tag="ACGI3L_003333"
     CDS             <1..321
                     /locus_tag="ACGI3L_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9199027.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKS
                     VYGK"
     gene            454..1824
                     /gene="hydA"
                     /locus_tag="ACGI3L_003334"
     CDS             454..1824
                     /gene="hydA"
                     /locus_tag="ACGI3L_003334"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HFG9199028.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKIAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            1842..3248
                     /locus_tag="ACGI3L_003335"
     CDS             1842..3248
                     /locus_tag="ACGI3L_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9199029.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     IRGTIKNRMEGHKWNSLY"
     gene            3320..3766
                     /locus_tag="ACGI3L_003336"
     CDS             3320..3766
                     /locus_tag="ACGI3L_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFG9199030.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            3805..4599
                     /locus_tag="ACGI3L_003337"
     CDS             3805..4599
                     /locus_tag="ACGI3L_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HFG9199031.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMTKALVVRMYNSIGGECDGK"
     gene            4589..6880
                     /locus_tag="ACGI3L_003338"
     CDS             4589..6880
                     /locus_tag="ACGI3L_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9199032.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            6881..8194
                     /locus_tag="ACGI3L_003339"
     CDS             6881..8194
                     /locus_tag="ACGI3L_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9199033.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            8230..9315
                     /locus_tag="ACGI3L_003340"
     CDS             8230..9315
                     /locus_tag="ACGI3L_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFG9199034.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            9551..10594
                     /locus_tag="ACGI3L_003341"
     CDS             9551..10594
                     /locus_tag="ACGI3L_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199035.1"
                     /translation="MQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEVKQ
                     EMTVMKEDMSEVKQEINVLKEDMSEMKQEMTVMKEDMSEVKQEINVLKGDMSEVKQEM
                     IVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEMTVMKEDMSEVKQEINV
                     LKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMK
                     EDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEI
                     QIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATS
                     KNWSDIVKLKSVK"
BASE COUNT         4285 a         1117 c         2169 g         3071 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggttatatg acgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctatgcaggt
      181 gaagctggaa taaaaactat aggatttggt ccttctaagg aaaatcttgc tcacacaata
      241 gatgagtata tagagcaaga acagttattt ataggaacag aaggttacta tggaatatta
      301 aaatctgtat acggaaaata atatttagtt cacaataaat tatttaaata tagtctagag
      361 gtgctgaata tagcaccttt agaaaataca attttaaata aagttttaca atacttagaa
      421 aatactttaa agcttaaaag ttaggaggta tatatgggaa caatactaag aggtggaact
      481 ataattacct ctgataagac ttatataagt gatttaagga tagaagatga aaagatagtt
      541 gaaataggaa ataacttaga aataaatggt gataaggtta ttgatgctac aggtaaaatt
      601 gtaattcctg gtggaataga cacacatact cattttgata tgaatgcagg ttctattaca
      661 actgcagata attttgaaac aggaacaaga gcagctatag ctggaggaac tactacaata
      721 ctagattttg cagaagccaa tgagggggaa aatctactgc aaggtgtaga agcatatcat
      781 aaaaaagcaa gtggaaattg ttattgtgat tatggttttc atatgacaat tacatgttta
      841 aataaagata catttaatca tatggaaaaa cttatttcag atgggatagt atcttttaag
      901 atgtatatgg catatgatgg catgaaagta gatgatggaa caatatacag ggttttaaag
      961 aaagcaaggg atttaggttg tatagttgga tttcattgtg aaaatgggga tttactagat
     1021 gtattgatag aagaaaatat acaaaatggt aatttggagc caaaatatca tccacttaca
     1081 agacctaaca tagttgagaa agagtctgtt tcaagacttg ctgatataac taaattatct
     1141 aattcaaaat cctatgtagt ccacttaagt tgtagggagt cacttgaaac tgtaaaaata
     1201 gctagagaaa aaaatataga tatgatagta gaaacatgcc cacagtatct attattagaa
     1261 gacaatttat ataataagga taaatttgag ggtgctaagt atgtaatgtc tcctccttta
     1321 agaaaaaaag aagacataaa ttacctttgg gaaggattgt ctagtggaga tattcaaaca
     1381 gttggcacag accactgttc atttaatttt aaggggcaaa aagacttggg aattgatgat
     1441 ttcagtaaga taccaaatgg agcacctggt gttgaacata ggttagcact tttatataca
     1501 tatggggtct tagaaaatag aataagtgta aataagtttg tggaagttac ttctacgaat
     1561 gctgcaaaaa tatttggaat gtatcctaaa aaaggtgaga tagctgtagg aagtgatgca
     1621 gatatagtca ttttaaatat caataaagaa gaaacaatta gttataaaac tcaaaaacaa
     1681 aatgtagatt atactccata tgaaggattt aaggttaaat gtaaagttga agatgtattt
     1741 ttgagaggaa atcatgtagt acaaagttgt aatgttaaag aacatccaac aggtcaatat
     1801 attaaaagaa aaattactaa ataatgcggg gggaaataag aatgatggat atacttatta
     1861 agaatgccat aatagtaact gtgaataaag agagagaagt tatttttgat ggggcattag
     1921 tagtaaaaga taacaagatt gctgatattg gaaattctaa agagatagaa agtaaatata
     1981 ctgatgttaa aaaaattata gatgctaaag gtaaagtttt attcccaggt tttataaata
     2041 cacataatca tttattccaa actttattaa aaggattggg agatgatatg gtacttaaag
     2101 actggttaga aactatgaca tttccagcag ctaactattt agagcccaaa gatacttatg
     2161 atgctgcaat gcttggatgt attgaaggac ttagaagtgg tataacaaca atggttgact
     2221 acatgtatcc tcatagtaag ccaggtcttt gtgatggaat aatagatgct tataaagaat
     2281 taggaataag aggaatactt ggaagaggat gtatgaatac aggagctcaa tttggagttc
     2341 atcctggaat aatgcaagat gtagaaacgg ttgaaaaaga tgtaagaaga ttgtttgaaa
     2401 aacaccataa tacagaaaat ggaagaatca aaataggagt agctcctgca gcaatatggt
     2461 caaattctca agaaatgctt gaaatgctat ggagagtagt aaaagaatat gatgatgctt
     2521 tatttacagt acatatatca gagactcctt ttgatagaga agcagcaaaa gaattgcatg
     2581 ggcaatatga catagatgtt ttagaaaaat taggaatact tggaccaaat gtgcttatgg
     2641 tacattgtgt gtatctaact gaaaaagata tggaacttac taaaaaatac gatatgaaag
     2701 tgtctcataa tacagcaagt aatatgtact tatcttcagg tgttgcacca gtgccagaaa
     2761 tgcttaaaaa aggaataaca gttagtttag gagtagatgg agccgctagt aataactctc
     2821 aagatatgct tgaacttatg aaattaacag cacttcaaca taaagttaat aagtgtgacc
     2881 cattagcaat gtcggcagaa aaagttcttg agttggcaac tatagatgga gcaagagcta
     2941 ttggaatgga agatgagata ggttcattgg agataggtaa aaaagcagac ttactaatat
     3001 ttaatccaat gctttcacca aaagcgatac ctatgcataa tccggtatct acattagtat
     3061 attcttctag tatgaaaaat atagagagtg ttatagtaga tggaaatata ataatggaag
     3121 attcaaaaat attgacagct aatgaagaga aagcattaaa agatgctcaa gatacagctg
     3181 agagactttg tataagagga actataaaaa atagaatgga aggtcataaa tggaatagcc
     3241 tttattaata aatgtaattt attcataaaa aagtatagta aaactttagc ttaaaaatat
     3301 gagttttgag gtgatttatt tgattatcaa atgtaccata aataataaag aaaaagaatt
     3361 aagtataaga ccagatgatt ttttagcaga tacattaaga gaaaatggat atgtaagtgt
     3421 taaaaaaggg tgtgatacag gctcatgtgg gttatgtaca gtgatggtaa atgacaaggc
     3481 cgtgctttca tgtaattatc ttactgctag agtagaaggt cagcatatta caacacttga
     3541 gggtgtcttg gatgaagcaa agaagtttgg agattttctt gcagacgaag gggctgacca
     3601 gtgtggattt tgtgctcctg gatttataat gatggtcttg gcaatgaaaa gagagcttca
     3661 aaatccaaca gaagaagaag ttatagatta tgtaaatggt aacctttgta gatgtacagg
     3721 atataaaggt caattaagag caatacataa atatttaaac acttagactt ttaagtgaaa
     3781 attaagttga tatggggaga gagtatgata actataaagg aatatgtagt tccaaaaagt
     3841 ttagatgaag cttatgaact gctaatatca agaaaaaaca acataatact tggaggatgt
     3901 ggatttttaa aactaggtag taaaaatatt ggttcagcaa tagatttaaa agacttagct
     3961 ttagattata taaatgaaac tgatgatagc atattaattg gagcagatac aagtttaaga
     4021 actttagaat taaataaggt tattaaaaat tactgtaatg gggtaatttc aaacgctgtt
     4081 tctaatatag taggagttca atttagaagt ggagctagag taggagctag cgtatttgct
     4141 aagtatggat tttcagattt aataccttca ttactagtgg tagatgcaaa ggttaagtta
     4201 tataaaaaag gggttatgaa cttagctgat tttttagaaa atgagcttga aaaagatata
     4261 ttaatagaag ttatattacc taaaaaagat gctataggtg tatttgattc tataagaaaa
     4321 tgtacaggtg attttgcagt attaaatgga gcaatgttaa aagaaggaag tatttataaa
     4381 attgcgatag gcgctagacc aagaagagca aaaattgcct ataaagcaag tgaaatatta
     4441 agtttagaaa atgatataga aaaagctggt gaagtatcaa gtgaagaact ttcatttgga
     4501 agtaatataa gaggaagtaa agaatacaga aaagatatga caaaagcctt agtagtgaga
     4561 atgtataata gtattggagg tgagtgtgat ggtaaataaa gaggtaagaa aaatagatag
     4621 tgaagccatt gttactggaa aaccaatata tacagaagat ttaatttttc ataaagatgt
     4681 tttaacaatt aagcttctta gaagtccaca tgcttttgcg aagataaaaa acatagatat
     4741 aaaaaatgca ttaaaggtaa aaggtgtagt aaacatattc acttacaaag atgttccaaa
     4801 ttatagatat tcaatggttg gagagtcata tccagaagca tcacctcatg accaattaat
     4861 acttgaagac gtagttagat atgtaggaga tgaagttgct ataatagccg ctgaagatga
     4921 aagggctgct attaaagcta tgaaacttat aaaagttgaa tatgaagtaa tgactcctat
     4981 attggatgca agagaatcgg aaggaaataa aattttaatc catgaagaag atgatttgtt
     5041 ttgtccattt gattttggat tggatgctac aaaaaatatt gtatcgagag aaaaaatggg
     5101 taaaggggat gtagaaaaag agtttaaaga aagtgatgta atagtagaac attcttatat
     5161 gactcaatca caagcccatt gtatgatgga aactcataga gcttatacgt atatagatac
     5221 gaatggcaga ttagtagtaa cttctgcaaa ccaatcagct tatcatatga gaagacaggt
     5281 ttctaaagca ctgggaatac ctctttcaaa agtgagagta ataaaaccaa gaataggtgg
     5341 aggttttggt ggaaaaaaca tagctgtaac agagatatat gcatcatttg taacttggat
     5401 gacaaaaaga ccagcaaaac taatttatac tagagaagaa acttttgcaa tgactaatac
     5461 tagacatcag atgttttttg atataaaaat tggggcagat aaagaaggaa acataaaagc
     5521 tatagatatg aaagcattga acaatacagg cgcttatggc gataatggac cttcagtttg
     5581 ctctgaatca ggtcataatg tacttccaac atataataat gtacctgcaa taaaatttga
     5641 tgggaaaact gtatatacta atttagttcc aggaggagca ttaagaggat atggagcaac
     5701 acaaggtaca tttgcacttg attgtgcaat tgatgaatta gcgcataaac ttaatatgga
     5761 cccaacagaa ataaagttaa agaatattat aaaaaaacaa actgaaggcg gaataatgaa
     5821 ttttccaata agaagttgtg cacttgatga atgtataatt agaggtaaaa aacttattgg
     5881 atgggatgaa aagtaccctg ttagggatat tggaaacaat aaggtgaggg ctgttggaat
     5941 gtctgtggga actcatggtt ctggtatagc caacatagac atggcaatag taaatatgag
     6001 gatggatgaa gatggaactt ataagttgtt ttctgggtct tcagacttag gaactggttc
     6061 tgacacaata cttgcacaaa tagctgcaaa agcattgaat acatctattg atagaatttc
     6121 cgtttataca ggagatacag atatgtgtcc atatgatact ggtgcatacg cttcttgtac
     6181 tacttatgta actggaaatg ctacaataaa atctgctgaa agtttaaaac aaaagatatt
     6241 aaaagtagca cagaagaaac tcgatttacc aatagatgat ttaatactat atgaagacag
     6301 agtttgttat agtgaagatg tagagaagtt tgttttgtta agtgaattag gaaaagaatc
     6361 tgttggtggt ggaaatcaag aagttttata ttcatctgaa tcttatggta tacaagagag
     6421 tgctaaacca ttcttagcag gatttgctga aatagagtta gataaaacaa caggggagtt
     6481 taaagtaata aattatgctt gttctacaga ttgtggtaca gttatgaatc ctgcacttgc
     6541 tagaatacaa gttgaaggtg gtgtaactca aggtataggg cttgcaatgt atgaagaccc
     6601 tagacatggt tctgatggaa agcttcaaac ttctaatcta ttacaataca aagttccaac
     6661 aaaaaaagat ataggaaaca taattgttga ttttgtagat aattatgagc caacaggtcc
     6721 atatggagct aaatctttag gagaaatagt tattcataca cctgcaccag caatagcaaa
     6781 tgcaatatac aatgccacag gagttcgtat aagagaactt cctataactt ctgagaaagt
     6841 ttatatggcc atgaaaaaat taaatcaggg aggtaaataa atgattgcta ttaaaagtaa
     6901 atacttaata tcttctgctg atgaaatata tacaaattct gctgttgtag tagaaaatga
     6961 cattataaaa gatatattgc caaatgaaga agttgaaata aaatataaaa atattgaaga
     7021 aataatagat aaatcagatg ctataataat gccaggattc gtcaatggtc atatgcatca
     7081 atatggagtt ctttctaggg gaataccggc aaatgtacat tttactgact ttgaaggttt
     7141 tttaaatgac tattggtggc catttataga aaatagaatt ggattaaaag aagtgaaggc
     7201 aacaactaaa gcatcagcaa tagaacttat agaatctggt gtggtagctt tttgtgatac
     7261 cctagaagct ccaaatacag aagaaggaac tttaattgag caaggaaaaa tactagaaga
     7321 aataggcatg aaagcgattt tatccttaga aagttgtgaa agaataagct ttgaaaatgg
     7381 acttagatgt ttagatgaaa attctaattt aataaagtgg agtagagaaa atagtaaatt
     7441 aataaatgga ataatgtgta cacatacaag cttcacatgt tctgatagat ttattaagaa
     7501 agctaaagaa gatgcaaaaa aattaaatgc accaatgcaa tttcatttat gtgagagtat
     7561 atatgagcca aactatgctg aaaaacactt tggcaaaaaa gcagttgact actataatga
     7621 tttagatata ttggatgaaa ctgtattagc atctcagtgt gtaaaagtaa atgatgaaga
     7681 aatagatata ttaaaagaaa aaggcgtaaa agtggttcat atgcctctta gtaactgtga
     7741 agtaggtgga ggtttttctc cagtaccaaa aatgattaaa aaaggcataa aagtggcact
     7801 gggtactgat ggatatataa atgatttttt tgaagttatg agaggtgcat ttttaatgca
     7861 taaatcagtt gaagaagatg catcagtaat gccagcaaat ttagtattta gaatggcaac
     7921 agagcatggt gcttatgtat taggacttca aaattctggt aaaatagcag ttggtaataa
     7981 ggctgatata atagttatgg aagatgaatt taaaactcct gtgactcttg ataatatatt
     8041 tgaccagata gtagttcagg gtaaaaaaga atttatatca aatgtataca tagatggtag
     8101 acatatttta aaagaaaaac agttagttga tttagataaa aaagctattg ttaaagaaat
     8161 gaaagaagtt gcttgtgaat tttggaaatt ttaacgaatg taaatatata tgaaaagggg
     8221 aagcagataa tgtataattt tttaggtaaa gaattaaaat caccacttat aataggttca
     8281 ggaccattaa catatagtgc agctggatgc aagatattaa gtgatgcagg agcaggggca
     8341 gttgtgacta agactataag aaaagaaaga gctataaatc cagcaccaca tatggttaga
     8401 aatacagcta atgctctttt aaataatgaa aaatggacag attttgagcc agagcaatgg
     8461 atagattttg aaataccaca aatgaaaaga gatgggactg tctgtatagc ttcaataggt
     8521 catacaattg aagaaagtag cgaattagta gagaaagttg caaatgcagg agctgacttt
     8581 attgaattag tatcttatga ctatagagat ttgataccaa tgcttaaaga tgcaaaggaa
     8641 agagtaaata tacctgtaat agttaaactt cctcctatga tagatgagat aggcgatttt
     8701 gctaaaaaat tagaagaagc aggagcagat gcaataactg cttgtgactc tgtaggacca
     8761 gcatttagaa tagacataga aacagggcaa cctttattag gtggaaatgg aataggatat
     8821 ttaagtggag aaactatcaa gccaataact ttacagagaa tatatgaaat aaaaaaacaa
     8881 gttaatatac caataattgg cttaggtgga tgtgtaagtg gagatgatgc cttagaaatg
     8941 attatggcag gtgctgactt tgttggtata tgttcagtag taattttaaa aggtgcacaa
     9001 gtaatatcta aaatacatga tgatttaaaa tctaatctta atagattagg atataatact
     9061 atagaaaatg cttgtggtat agtacataat catatgggag atgttaatga aagacttagc
     9121 tttgagttta cttatgatga agaaaaatgt actaaatgta agatgtgcga gagagtttgt
     9181 gcatatcaag cgagaaaatt gaatgataag atggaattga atgaagaaga gtgtagatat
     9241 tgtggacttt gtatatcagt ttgtaaacca aaagcacttg gaagaaaaat ttcatgttca
     9301 gagctgaatg tatagattat tttataaaaa acaaagtttt aaataaaaat aagaaaggct
     9361 atctcaaaga gataagcctt ttttgttgtt gaccttattt ttgtttattt gtagttattt
     9421 tagatattaa ttagttttga agtaataaag tgaatcaatt ttgtttaatt aaaattttaa
     9481 taattctgat atatatgtta acattgtata gcatttgtgt aaaatgttat aataattaat
     9541 agggatggtg atgcaagtgc aagagaagat tttagagtta ttatatacta taaatgaaga
     9601 tgtagttagc ataaaaaatg atatgtcgga agtaaaacaa gaaataaatg tgttaaaaga
     9661 agatatgtcg gaagtaaaac aagaaatgac tgtaatgaaa gaagacatgt cggaagtaaa
     9721 acaggaaata aatgtattaa aagaagatat gtcggaaatg aaacaagaaa tgactgtaat
     9781 gaaagaagat atgtcggaag taaaacagga aataaatgta ttaaaaggag atatgtcaga
     9841 agtaaaacag gaaatgattg taatgaaaga agatatgtcc gaggtaagac aagagataaa
     9901 tataatgaaa gaggatatgt ccgaggtaag acaagagata aatacaatga aagaggatat
     9961 gtcggaagta agacaagaaa tgactgtaat gaaagaagat atgtcggaag taaaacagga
    10021 gataaatgta ttaaaagaag atatgtccga agtaagacaa gagataaata taatgaaaga
    10081 agatatgtcc gaagtaagac aagaaatgac cgtaatgaaa gaagatacat cagaggtaaa
    10141 acaagagata aatgtaatga aaaaagacat gtcagaagtg agacaagaaa taactgtaat
    10201 gaaagaagat gtttccgaag ttaaatcaga agtaaacttt atgcaaaata aaataaataa
    10261 cattaatgaa gatatgaatg gaattaagga cgaggtatcc atagcaaatg aaaaattata
    10321 tggaattgaa attaagattg atagtctaga atgtgaagat aaatcaatga aagagataca
    10381 gatagaacag aataatattt taggaagttt attacataat tctgaaataa ataaagctac
    10441 tcatgataat atagaacata acatagcata tataaaaggt gacactaatt ctataaaaga
    10501 ggatatagct gaaataagaa gagacttaaa tttagtagag ttagccacta gtaaaaattg
    10561 gagtgatatt gtcaaactaa aatcagtaaa gtagtatttt aattcactaa tttatcatcc
    10621 acaaactaag aattttatat aa
//
LOCUS       DAYAKB010000107        10565 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.108, whole genome shotgun sequence.
ACCESSION   DAYAKB010000107 DAYAKB010000000
VERSION     DAYAKB010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.108"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1184
                     /gene="dnaA"
                     /locus_tag="ACGI3L_003342"
     CDS             <1..1184
                     /gene="dnaA"
                     /locus_tag="ACGI3L_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFG9199036.1"
                     /translation="DFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSD
                     STDLNYRVLYPNLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLG
                     KTHLMHAIGHHIVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLID
                     DIQFIAGKERTQEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITD
                     IQAPDFETRIAILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSN
                     RVISFDLATEALKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQ
                     IAMYLTRELTDLSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLK
                     G"
     gene            1426..2532
                     /gene="dnaN"
                     /locus_tag="ACGI3L_003343"
     CDS             1426..2532
                     /gene="dnaN"
                     /locus_tag="ACGI3L_003343"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFG9199037.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            2669..2875
                     /gene="yaaA"
                     /locus_tag="ACGI3L_003344"
     CDS             2669..2875
                     /gene="yaaA"
                     /locus_tag="ACGI3L_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFG9199038.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            2893..4008
                     /gene="recF"
                     /locus_tag="ACGI3L_003345"
     CDS             2893..4008
                     /gene="recF"
                     /locus_tag="ACGI3L_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFG9199039.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            4009..5910
                     /gene="gyrB"
                     /locus_tag="ACGI3L_003346"
     CDS             4009..5910
                     /gene="gyrB"
                     /locus_tag="ACGI3L_003346"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFG9199040.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            5930..8356
                     /gene="gyrA"
                     /locus_tag="ACGI3L_003347"
     CDS             5930..8356
                     /gene="gyrA"
                     /locus_tag="ACGI3L_003347"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFG9199041.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            8425..8721
                     /locus_tag="ACGI3L_003348"
     CDS             8425..8721
                     /locus_tag="ACGI3L_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFG9199042.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            8721..8981
                     /locus_tag="ACGI3L_003349"
     CDS             8721..8981
                     /locus_tag="ACGI3L_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFG9199043.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            8993..9310
                     /locus_tag="ACGI3L_003350"
     CDS             8993..9310
                     /locus_tag="ACGI3L_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HFG9199044.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            9314..9721
                     /locus_tag="ACGI3L_003351"
     CDS             9314..9721
                     /locus_tag="ACGI3L_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9199045.1"
                     /translation="MACETIKMEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVA
                     VSEACTNAIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLG
                     LFIIKTLMDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            9721..10494
                     /locus_tag="ACGI3L_003352"
     CDS             9721..10494
                     /locus_tag="ACGI3L_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HFG9199046.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
BASE COUNT         4328 a         1086 c         1965 g         3186 t
ORIGIN      
        1 gtgattttaa taaagatatc ttagagaata gatatttaca tttaattgaa gatgctatta
       61 gtcaactgtc attaaaaaaa tataatatta aatttgtatt gagcgaaaaa gaggttgctg
      121 atttaaattc tgatagcaca gatttaaatt atagagttct ttaccccaat ctaaatccaa
      181 aatacacatt tgatacattc gttattggta atagtaatag atttgcacat gctgcatgcg
      241 ttgcagttgc agaatctcca gctaaagctt ataacccact ttttttgtat ggaggagttg
      301 gattaggtaa gactcaccta atgcatgcta taggtcatca tattgttagt caaaaaaaag
      361 actcaaaagt agtttacgtt tcttcagaaa aatttactaa tgaacttata aactctataa
      421 aagacgataa aaacgaagaa tttaggaata aatatagaaa cgtagatgta ttactaatcg
      481 acgatattca atttatagca ggaaaagaaa gaactcaaga agagtttttc catacattca
      541 atactcttca tgaagcaaac aaacaaataa ttatatctag tgatagaccg ccaaaagaca
      601 tacctacact agaagatagg ctaagatcga gatttgaaat gggacttata actgatattc
      661 aagcacctga ctttgagaca agaattgcta tacttagaaa aaaggctcaa ctagaacgta
      721 tagatgtgcc aaatgaggtt atgtcatata tagcaaaaaa tattaagtca aacataaggg
      781 aactagaagg tgcattaact agagtggttg cttattcttc tcttagcaat agggtaatat
      841 cttttgatct tgctacagaa gctttaaaag atattataac aacttctaaa aatgaagaaa
      901 taaatgttct cagaataaaa gaaaaagtat cttctgtatt caatttaaag atggaagatt
      961 ttaattctaa aaaaagaaca cgttcaatag cttatccaag acagatagct atgtatttaa
     1021 cgcgcgagct tactgattta tcccttccta aaataggtga agagtttggg ggtagagacc
     1081 atacaacagt aattcatgct catgacaaag tatctaagga tatagaagaa agtgaagaaa
     1141 ttaagactaa aatagacaaa attatatcag atttgaaggg ataatttata cacaattgta
     1201 tgtttatatc tcttgaataa cctgttaata ctttttttga acaaaaatta ttaacaaatt
     1261 atcaagtcta aaataacaaa gatattaaca tcttatacac atgttaatat ctttgtattt
     1321 ataatgttat acatacttat taacattatc aacaacacct actactatta ctactatgat
     1381 tttaacttat ttttatatat aaaaagccag aggaggttat ccacattgaa aataatttgt
     1441 aatcaaaaaa tcctagcaaa tagaattgga attgctcaaa aagctattaa tggaaaaaca
     1501 acaatagaat tattaaaagg tatacttata tctacagaag aaggtcaatt aaaacttact
     1561 ggatatgatg ctgaaatagg aatagaaact tatgtacaag cagaaatcat agaaaaaggt
     1621 gatgttgttg tagatgcaag gctatttgga gatataatta gaaaattacc agattccttt
     1681 gttgagatag aaactgattc agaaaataat atttacataa attgtgtaaa ttcaagattt
     1741 aaaattaaag gttatgcagc aaaagaattt cctaaattac cagaattaaa tgaagaagat
     1801 ttatatagca tacctcaaga aatcctaaaa aatatgatta aacaaactgt atttgctatc
     1861 tcacaggacc aaacaaaacc tgttttaatg ggagaacttt tagaaattgt agatagaaac
     1921 ttaaatttag tagcaattga tggatataga ttagctgtaa aaagttgttc ggttgatagt
     1981 ttaactgaaa atataaaagt cataattcct ggaaagacac ttatagatgt aaatagtttg
     2041 ctttctggag aggataatgt taaagttgga tttaatgaaa aaaatgctat ttttataatt
     2101 aatgatacga aaattattac aagattgctt gaaggagatt ttattgatta taaaaaatta
     2161 ttgccaagag aacataacag cagagttaaa ttaaatacta aggaactttt aaatagtata
     2221 gagagagcgt ctttattgtc tcaatcagaa aaaaataatc ttataaagtt atctataaga
     2281 gataaagtaa tggcaattac ttctaataca gaaaaaggaa atgtgtatga agaagttgaa
     2341 atagatttag atggagatta cctagatata gctttcaatt ctagatattt tatcgaaggt
     2401 ttgaaaaata tagataatga ggaaatattt atagaattta ctacaaatgt aaatccttgt
     2461 ataattaaac caacagatga tgttaattat atttacttac tgcttccagt aagaatatca
     2521 tcaaatatat agcagacatg aaggagttgt cttttgtaga aaatttttct aatcttagac
     2581 aactcctttt ataagcatat ttatggtata atatactttt agtgtatcaa taggaatttg
     2641 tttaaaatag tgacaaggag gaactattat gactgaaata actatagaat cagaatatat
     2701 aaagttggat caatttctta aattagcaga gattgcatca acaggaggtc atgcaaaatt
     2761 tttaattcaa gaaggtttag tgacagtaaa tgatgaaata gaattaagaa gaggaaaaaa
     2821 gataaaatca ggagatatag ttgaaataga aggaactaaa ataaaagtat tgtaaaaaaa
     2881 ggagaacttt ttgtgaaact taaaagtttg caacttgtta attttagaaa ttataaaaag
     2941 ttgcatctgg aatttaatgg gaaagtaaat ctacttgttg gtaaaaatgg tcaaggaaag
     3001 acaaatatag tagaatctat ttatatgctt tcttttggaa aatcatttag gactaacaaa
     3061 gataaagaaa tggttagatt taatagtgaa aacttatata ttggaggaag tttttcaaaa
     3121 tataataaat atagtctaat agagctaatt attggaaaag ataaaaaagg gataagaata
     3181 aataaagttc ctttacaaaa gatacaagaa ctacttggca acttaaatgt tgttatattt
     3241 tctcctgagg atttaaggtt ggttaaagag ggtcctaaag aaagaagggc atttatagac
     3301 aaagagatta gtcagattat acctaaatat tataaatatc ttaccaatta taataaaaca
     3361 ctttctcaaa ggagtagggt gcttaaaaat atacatgttg atgaagcttt attagatgta
     3421 tatgatgata cgttagcaaa gtatggaagt tatatttata ttttgcgtag agactttata
     3481 aaaaagatag ctaatatatc tgaaaatatg catatgaatt tgactaatgg agttgaaaga
     3541 ttatcaattc gatataaaaa tcaaataaat ataactgatg aagatactat agatacagta
     3601 tataataaat ttttagccaa gttgtcatcg aatagaccta atgatataga atctaagact
     3661 accagatatg gtatacacaa agatgactta aatatattca taaatgattt agatgcaaga
     3721 ctttttggtt cacaaggtca acaaagaact gcttcaatat cattaaagtt atcagagata
     3781 gaattaataa aaaatgaagt tgaagaatat ccagtattaa ttttagatga tgtttttagt
     3841 gagttagatg aagcaagaca aaaactttta gtaaataatt taagcaatgt tcaaatgttt
     3901 ataacaagtg ctgaagtttc acataaaaaa atatttgatg aaaaaaatgt tacaatattt
     3961 aatattgaaa atggcgatgt tattagcata gagaatggag gaaattaaat gaaacaagaa
     4021 tacggtgcaa gtcagataca agtattagag ggattagaag ccgttagaaa aagaccaggt
     4081 atgtatattg gtagtacaag ccctagaggt ttacatcact tagtttatga agttgtagat
     4141 aatagtatag atgaggcttt acaaggatat tgttcagaca tatatgtatc tattaatgaa
     4201 gatggcagtg ttttagtaaa agataacgga agaggtatac ctgttgaaat acatcctaaa
     4261 actggtaaat caactttaga aacagtatta actaatcttc atgcaggagg aaagtttgga
     4321 ggcggaggat ataaagtatc tggaggtctt catggagttg gtgtttctgt agttaatgca
     4381 ttgtcaaaat ggatggtagc agaggtttat ttaaacggaa agatatataa gcagacatat
     4441 gagaaaggat tgccaacatc taagcttgaa gtagttggag aatctcaaga taaaggaaca
     4501 atgattcaat ttatgccaga tgagacaata tttgatgaaa tagagtttaa atatgaaaca
     4561 ttggagtata ggcttagaga actttctttc ttgaataaag gaataaaaat agtatttgaa
     4621 gataaaagag aaggacaaga aaaaagaaaa gaatttcact atacaggtgg tttggtagaa
     4681 tatattaagt atttaaataa atctagaact ggtatacatg atgacatagt ttatatagat
     4741 aaaaaggttg atgattgttt tgttgaacta gctatgcaat atacagatgg ttatacagag
     4801 aacatatatt cttttgcaaa caatataaat acacatgaag gtggttctca tttaagtgga
     4861 tttaaagcag ctcttactaa aactgtaaat gattatgcta agagaaataa atttttaaag
     4921 gaaaatgatg ttaacctact tggtgaagac ataagagaag gtcttacagc agtagtatca
     4981 gttaaattac cagaacctca atttgaaggt caaactaaaa caaagctagg taatagcttt
     5041 atgagaggta tagttgatag tgtaacagtt gatgaactgg ggtctttcct agaagaaaac
     5101 ccatcaacag caagaatcat agttgataaa gctttaagag cacaaagagc tagagaagct
     5161 gcaaaaaaag caagagaatt aacaaggaga aaaagtgtat tagaaagtac atctttacct
     5221 ggaaaacttg cagattgtgc agaaaaagat ccatctaaaa gtgaaatatt cttagtcgaa
     5281 ggggattcag cgggaggttc agctaaacaa ggtagagata gaaatagtca agctatactt
     5341 ccattaagag ggaaaatact taatgttgag aaatcaagac tagataggat actatcttca
     5401 gatgaaataa aaaatatgat aacagcttat ggttgtggta ttggagaaga ttttgatata
     5461 gataaggcta ggtatcataa aattataatt atgaccgatg ctgatgtaga cggagcccat
     5521 ataagaactt tattattaac attcttcttt agatatatga gacctcttat agatgagggg
     5581 tatgtttatg cagcacagcc acctttatat aaagtgacaa agcaaaagaa ggaacattat
     5641 gtttactcag ataaagagtt aaatatctta ctagatgaaa ttggaagaaa tggtgttgaa
     5701 cttcaaaggt acaaaggtct tggagagatg aatgcagagc aattatggga aacaactatg
     5761 aatcctgaga caagaacttt attacaagtt actgtagaag atgctgcaat tgcagatgaa
     5821 gtattttcaa tgcttatggg tgataaggtt gctccaagaa aagaatttat agaagaaaat
     5881 gcaagatttg ttagaaactt agatatatag agagagggga ttagtataca tggaagaaaa
     5941 taacaaaata ctccctattg aaatagcgga agaaatgaaa aaatcgtata ttgattattc
     6001 aatgagtgtt atagctggac gtgctcttcc tgatgttaga gatggtttaa agccagttca
     6061 tagaagaata ttatattcaa tgagtgagtt aaatttaact ccagataaac catacaggaa
     6121 gtcagctcgt attgttgggg acgttttagg taagtaccat cctcatggag atactgctgt
     6181 ttattatgct atggtaagaa tggcacaaga tttttcaact agagcacttt tagtagatgg
     6241 tcatggtaac tttggttctg ttgatgggga ttcaccagct gctatgcgtt atacagaagc
     6301 taaaatgagt aaattatcat tagaactact gagagatatt gaaaaggaaa ctgtagactt
     6361 taaaccaaac tttgatgagt cgttaaaaga gccttcagta ttgccagcta gatatcctaa
     6421 tttattagta aatggctcaa atggtatagc tgttggtatg gcaacttcaa tacctccaca
     6481 taatttagca gaagtaattg atgcaactgt atatttgata gataatccag agtgtagtgt
     6541 agatgattta ataaaatttg ttcaaggacc agatttccct acagctgcaa ttataatggg
     6601 aaaagaaagt atagcagaag catacagaac tggaagagga aaagttaaag ttaggtctag
     6661 agcttttata gaagagctac caaaaggaaa acagcaaata atagttacag aaatacctta
     6721 tcaagtaaat aaggctaaac tggttgaaag aatagcagag ttagttaaag aaaagagaat
     6781 agaaggtata tcagacctaa gagacgaaag taatagaaat ggtatgagaa ttgttataga
     6841 attaaagagg gatgctaatg ctaatatagt attaaataat ttgtataaac attctcaaat
     6901 ggaagatact tttagtataa taatgcttgc acttgtagat ggtcagccaa gagttttaaa
     6961 tcttaaacaa atattatatc attatattaa acatcaagaa gatgttgtta caagaagaac
     7021 taaatttgaa ctaaataaag ctgaagcaag agcacatatt ttagaaggat taaagattgc
     7081 tttagataat atagatgctg ttataagctt gataagagct tcaaagactg ggcaagaagc
     7141 taagctaggt ttaatagaaa aattcaaatt aactgaaatc caagcacaag ctatattaga
     7201 tatgagactt caaagactta caggtttaga aagagataag atagaagctg aatatgaaga
     7261 tttaatcaag aagataaata gattaaaaga gattttagct gatgaaagat tacttttaaa
     7321 tgtaataaag gatgaaatta caataataaa agaaaattac tctgatgaga gaagaacaga
     7381 aataagacat gctgaaggcg aaatagatat gagagatctt ataagtgatg aagaaatagc
     7441 aataactctt actcactttg gatatataaa aaggcttcca tctgatactt ataagagtca
     7501 aaaaaggggt ggaagaggta tttcagcact tacaactaga gaagaagatt ttgtaaggca
     7561 cttggtaact acaactactc atagtagact attattcttt acaaataaag gtagagtatt
     7621 taaattaaat gcatatgaaa taccagaagg taagagacag gctaaaggta ctgctatagt
     7681 gaatttactt caattgtcag cagatgagaa aattgctact ctaataccta ttgatggtaa
     7741 tgatgaaaat gaatatttat tacttgcaac gaaaaaaggt attgttaaaa agactaagag
     7801 agaagagttc aaaaatataa ataaatctgg tcttattgca ataggtttaa gagatgatga
     7861 tgagcttatt ggagtagaac ttacagatgg aaaacaagaa gtacttttag taactaaaga
     7921 aggtatgtct ataagatttg atgaaaatga tataagatat atgggtagaa cagcaatggg
     7981 tgtaaaaggt ataactttaa gtaaagaaga ttttgttgtg tctatgaacc tttgcagtaa
     8041 aggtacagat gtgttagttg taagtaagaa tggttttgga aagagaacaa atatagaaga
     8101 gtatagaagt caaataagag ctggtaaagg aattaaaact tataatatat ctgaaaaaac
     8161 tggtacaatt gtaggtgcag atatggtcaa cgaagatgat gagataatga ttataaattc
     8221 tgatggagtt cttattagaa taagagtcaa tgaaatatca ctgtttggaa gagttacaag
     8281 tggtgttaaa ttaatgaaga cgaatgatga agtcaatgta gtttcgattg ccaaaataaa
     8341 tattgaagaa gaataggata aatatcctat tctttttgta taatgtagtt agataaaaat
     8401 ttaaaattga aaggagtaat tgttatgtgc aataaaagaa gttgtaaaaa aggtggattt
     8461 ttattattag gagctatttt agggtttata tttggtatgt tttttgcacc taaaaaaggt
     8521 tctgaactaa gaaaagaaac aaaagagaag tttaatgatg tcaaagaaaa tccaaaagaa
     8581 gttctacatg aaacatttaa tgatgttaaa gagagaataa taaatttagt ggatgatgat
     8641 aataatgaag aagatataaa gatttcagaa gaagatatag taataagtaa aagctttgat
     8701 gatgagggag atgttaacta atgaatgcat gggggtggca aattggagca gtgttagtag
     8761 gaagctctgc tcttatagta gcaatttatt tagctaaaac tctaaacagc ataaataagg
     8821 ttgttgaaaa ggcatataag attgtagatt ataatgaaag acatatacaa gatattgttg
     8881 aaaatgcatc atcaatatca aagggaatag atgatatagt ttatgtaatt aataaaatat
     8941 tgagtatagg aaatatattt aaaattatta aaaggaaata ggaggttttt acatgtctat
     9001 gaatattgat tcaaatttag attcacaaaa taaattttgg aatgtttgtc ttgatggaga
     9061 acttgatgtt tctacagcag ataaactaaa ggaacattta catgctttaa tagaaaaaaa
     9121 tatgttagat gtaaagatta atcttaaaga tttagattat atagactcaa caggcttagg
     9181 agctatgata ggtgtattaa aaaaattaaa aataaatgaa aaagagatat acatagtaaa
     9241 tcctaagagt aacgtaagaa agatttttac tataacaggt ctagataaaa tatttaaagt
     9301 ggagggataa actttggctt gtgagactat aaagatggaa attactacaa atccagatta
     9361 tgttagtata ataagattaa cagcatctgg aattgccaat aagatgggtt ttccaataga
     9421 tgatatagaa gatataaagg tagcagtatc tgaagcatgt acaaatgcaa taaaacacag
     9481 taaagatgat gtgtttaata tagtatttaa tattttagat aatgcaatta atatagaaat
     9541 tcaagataat ggaaaaggat atgatgttag ctcaataagt acaccagatt tagagaatcc
     9601 aaaagagagt ggtcttggat tgtttataat taaaacttta atggatgatg tagatattga
     9661 atcagaacat aatcaaggga caaaaataaa aatgactaaa tatttaggag ttgatattta
     9721 atgaaaaatg tagctaatgc tacacattac ctaaatatgg atacaaaaga gctatttaat
     9781 ttatataata aaaataaaaa tgtagacatt agaaatattc ttattgaaag acatctgtat
     9841 ttagcaagat tgttagctaa gaagtatata aacaaaggtg ttgattttga agatatatat
     9901 caagttgctt cattggcatt aatttatgct attgatagat atgatgttga gaaaggattt
     9961 gagttctcca gctttgcaac accaactata gtaggagaaa taaaaaagta ttttagagat
    10021 aaggtatgga cacttagagt cccaagaaga atacaggaat taagcaaaaa gataagtgat
    10081 gcgaagatta aattagaaca agaaaataag aagcatccaa aggtaaaaga tatagctgat
    10141 tatataggcg ttagtgaaga agatgtttta gaggctatgg aggcttctta tggatatcaa
    10201 ccaatgtctt tggattcatc aagtaatgat gattcagagg ataaagatat aactcttatt
    10261 gataagattg gaaaagaaga aggtaacttt ggaagtatag agtatgaaga ttttattaat
    10321 aagtttattg aaactttaaa tgaattagaa gttaaaattt ttaaagatag atttttcttt
    10381 gataaaacac aatctagtat agctaaagaa ctagggatat cacagatgac tgtttctaga
    10441 ctagagaaaa aggtagtaga gaagctgaaa aaagaatatg aaaaaaattt ataaaaaaat
    10501 ataaaaaaag tattgaccta ctgttttaaa gatggtatag tattacttgt acttgaaaaa
    10561 aggaa
//
LOCUS       DAYAKB010000108        10458 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.109, whole genome shotgun sequence.
ACCESSION   DAYAKB010000108 DAYAKB010000000
VERSION     DAYAKB010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.109"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            122..679
                     /locus_tag="ACGI3L_003353"
     CDS             122..679
                     /locus_tag="ACGI3L_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9199047.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
     gene            complement(1048..1521)
                     /locus_tag="ACGI3L_003354"
     CDS             complement(1048..1521)
                     /locus_tag="ACGI3L_003354"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9199048.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            1820..2587
                     /locus_tag="ACGI3L_003355"
     CDS             1820..2587
                     /locus_tag="ACGI3L_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HFG9199049.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPYF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     misc_binding    2805..3018
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3272..4306
                     /gene="argC"
                     /locus_tag="ACGI3L_003356"
     CDS             3272..4306
                     /gene="argC"
                     /locus_tag="ACGI3L_003356"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HFG9199050.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            4347..5564
                     /gene="argJ"
                     /locus_tag="ACGI3L_003357"
     CDS             4347..5564
                     /gene="argJ"
                     /locus_tag="ACGI3L_003357"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HFG9199051.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            5579..6439
                     /gene="argB"
                     /locus_tag="ACGI3L_003358"
     CDS             5579..6439
                     /gene="argB"
                     /locus_tag="ACGI3L_003358"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HFG9199052.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            6469..7656
                     /locus_tag="ACGI3L_003359"
     CDS             6469..7656
                     /locus_tag="ACGI3L_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HFG9199053.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            7765..8787
                     /gene="argF"
                     /locus_tag="ACGI3L_003360"
     CDS             7765..8787
                     /gene="argF"
                     /locus_tag="ACGI3L_003360"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFG9199054.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            8914..9531
                     /locus_tag="ACGI3L_003361"
     CDS             8914..9531
                     /locus_tag="ACGI3L_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HFG9199055.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(9751..>10458)
                     /locus_tag="ACGI3L_003362"
     CDS             complement(9751..>10458)
                     /locus_tag="ACGI3L_003362"
                     /inference="COORDINATES: protein motif:HMM:TIGR00035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HFG9199056.1"
                     /translation="IIFMNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFP
                     KMMIYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKES
                     INIPILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKL
                     NNLIQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDS
                     SKCLAESVVNKYLKLVK"
BASE COUNT         4199 a         1030 c         1800 g         3429 t
ORIGIN      
        1 taattaaact gtcaagattt tataatagta taaagaattt tataaattac aataattgac
       61 gaaactaatt agattagcta aactaataaa gtaattaatt ttaaatgaaa gagggaaaat
      121 catgcgtgtt agtagagaaa tagttataca agctacatca gatatagtta ataaagatgg
      181 gcttaacaaa gtttctttaa aagttattgc agaaaagcta ggaatacgta caccatcttt
      241 gtacaatcat atagaaagtc tagatgattt attacttgaa gtagctcata aaggaatgag
      301 agagatgaat agtcaaatga taaaggcgac tattggaaat tttggagata cagctataaa
      361 gtgtataagt atagcatact ttaattttat aatttctaat cctggtgttt atgaaacaat
      421 tcagtgggct acttggcatg gaaataatga aacattagaa atctttgatg aatataaatc
      481 cttattagaa aaacttattc tttcttgtaa tctaaataca aagaatacag gtgaagtatt
      541 aaacttaata atgagtgtac ttcatggtta ttcgactttg caacttggga aatcactttt
      601 gagtaaagaa gaagctataa aaggtttagc cgattctatt gatactgtgt tattaggtat
      661 tcataaaaaa tatgattaag gaggtaaata aattatttta acttatttat tgaacacttc
      721 attatggggc atgtaaatta aatttttatc atttgtacca aaggaaaatc aacaggagaa
      781 cagtatattt taagaatatt tattttcaaa tgcccaatat tgtttacaaa gaagagatat
      841 aaagagaaac aacatagttt atgtttaata attgaattaa tttatatgtt aatcaaaaag
      901 gatatcaaaa aataaattat agttcatatt agtaaggatt ttaaagtata ttattaaaaa
      961 acaaaaaaga tagtattatt ttaaatcttg gtttaaaagc aaagtaacta taaaatattt
     1021 aagagacttt gctttttatt taatttatta tattaacaat ttcataggtg taaaacgtat
     1081 accgtcaaca atttgctcaa cagcagtatc tttaaatcct aatttatgat aaacttcaac
     1141 agcataaggt gatgaattta cagttatttc agttaaatta aatttattac aaatacagta
     1201 ttgtatgcct gtagtcatta atttttttgc aacaccatgt ttatgatagt ttttatctac
     1261 aaataacata catatatgat ttaaatttct aatagctaag actccaataa gttttttaga
     1321 gtcaaaacaa ccccaaaaga agagagtttt ttctttgatt ttttcaataa tagagttata
     1381 ttctataaat tgatgaaatg tcgtaattcc ttcatcacaa taatctggag attcaaattc
     1441 ttcaaatacg ttccagatta agtctaatgc atttttaata tcatcttctt ttaattctct
     1501 tattaagtat tctttgaaca ttataaacaa cacctttatt attattttaa ttataattat
     1561 atatcttaaa taaattcaat tcaatacaat ttgttttata aatttagaat attatgataa
     1621 tatataattt atattatagt gtagttagac catagaatgt atttaattat atatacaatt
     1681 taataattca gataatctta aaataatatt atgtaaaata aaaatatata tgacatgatg
     1741 ttgttgtatt caaaatatta agataaaaat atatagaata tatttaaaaa ttattatgca
     1801 attagaaaag gagataagta tgcagattat tgatataaat ataaataata ttgacaatga
     1861 acatatatgt tgttcaattt ctgaaaaaaa aggagaaaat tgtgtttttt ctaaaaaagc
     1921 ttggatgaaa aataattttg ataaaggtct agtctttaaa cgatttgatg taagaggtaa
     1981 agcttttata gaatatattc cagcagaaaa tgcatggtgt cctattactg cggacaatta
     2041 tatatttatt aactgttttt ggatatctgg aaaatttaag ggtcaaggat attctaatct
     2101 attgctacaa gagtgtgttg atgatgcaaa atcaaaaggt aaatatggat tagttgtgct
     2161 ttcgtctagt aaaaaaatgc cttttttatc tgatgctaaa tatctaaaat ataaggactt
     2221 ttgtttagca gatacatcag aaccaaatta tgagctatta tattttcctt ttactgataa
     2281 tgctcctatt ccatatttta agaattgtgt aaaaaaaaga aaattaaatg agaacggtat
     2341 agttttatat tacagtaatc agtgtccaca tacggaaaaa tatgctccta ttttgaaaaa
     2401 aattgcaaat tctagaggta ttgatgtaaa tcttataaaa ttcgaaacag caaaagaagc
     2461 acaaaatgct cctgcaccat ttactacata cagtcttttt tttaatggtg aatttgtaac
     2521 caacgagata ctttctgaga aaaagattga gaaattttta gataccaaca ttaaaaaatt
     2581 taactaaaaa gagatgtaaa tattgtattt tgaaaatata ttattttata atttaatata
     2641 ttttggatgt tttttaaatt gacgaatgaa atataaaaat tatatcgcaa tttagataca
     2701 aaatgctgga aattaaccat atagaaaata tttccaaaaa tttaaaaatt atattgacaa
     2761 agttaaaaaa ataaactatc atataaaaca ataagaaaat aaattgaaat cctgtgaaaa
     2821 agagagtagc ataaagctag ttgatagaga gctgggaatg gtggaagcct agtaacgaat
     2881 tttattgtga atagagcttt ggaggagatt accagaagta atagtatggt aattggtgaa
     2941 tctcgcctta agagattaga gtgggtaaga ttatcttatc aattagagtg gtaacgcggg
     3001 tgtatattcg tctcttggtc tttgaccaag aggctttttt aattttaaat gtacattttg
     3061 tagatacttt ttaatttgag ttttaatgat tattgtaatt ttaccaataa gagtggtacc
     3121 gcggaaaatc gcctcttagt atttataatg ctaaggggtt ttttgtttta attagagtat
     3181 tttaatctac gtattatcaa atgattatca tatagtaaag tggaaagata ggattttaag
     3241 actatttgaa tataaaaatg gagggaacaa aatgaataaa ataaaagttg gtattattgg
     3301 tgcaactgga tatgtcgggg cagagttgat tagattatta atgaatcatg ataaagtcga
     3361 agtgacagcg ataggttcaa attcgtatgt tggaaaagat atagttgata tatatccaag
     3421 tataggatat aaaaataaca tgatatgtat agaaaatgaa aaagttatag atatgtgtga
     3481 tgttgtattt acagcccttc cacatggagt tagtgaaaag tttgtaataa aggcaattaa
     3541 atcgaaaaag aaagttatag atttaggtgc tgactttaga ataaaagatg aagaagtata
     3601 tagtaaatgg tatggagtat cttttataga taaaatctta cataaaaaag ctgtatatgg
     3661 attaagtgaa atatacaaag aagatataaa agatgcagat ataattgcaa atcctggatg
     3721 ttatccaact agtatttctt taccattgat gccattacta agttctaaat tgataaaaaa
     3781 taataatata ataattgatt ctaaatcagg tcttacaggt gctggtagag aattatcgat
     3841 tagtagtcac tttacggagg ttaatgaaaa tatcactgca tataaaatag ggaagcacag
     3901 acatactcca gaaatagaac aaaatttaag tgaatcctgc aaagaaaaag taagtgtagt
     3961 ttttacacca aacttaatcc cagtaaatag gggaatctta tcaactatat attgtacaaa
     4021 agaagataat atttctataa atgatataca taggaaatta actgattatt atgaatttaa
     4081 agaatttata gaaattcttc cattagataa ggtagcttct ttaaagaatg ttagattctc
     4141 aaataaatgt gtaatatcat tacatgaaaa tggagataca ttgataatct gttcagctat
     4201 agataatatg attaagggag cagcaggtca agctatacaa aacatgaata taatatttgg
     4261 tattgaagaa aatacaggtt taaaaaatat tgcaccatca ttttagaaat aaaaaatact
     4321 aaactcatat aattaggagg ataaatatgg agattataaa gggtggagtt acagtttcag
     4381 aaggattttt tgcttcaggg attcactgtg gcttgagaaa aaataaagaa aaaagagatt
     4441 tagctttggt ttattcagat gttttatgtg atgcagcagc agtagtaact caaaataaag
     4501 taaagggcaa tcctgtttat gttacacagg aacacattaa aaatggaaaa gcacaagcta
     4561 tcatagtaaa tagtgctaat gctaatacct ttaatggaaa agaaggactt ataaatgctt
     4621 ataaaatggc taaattcacc agtgataaat taaatattaa agaaagtgat gttttggttg
     4681 catctacagg tgttatagga aagccattaa atatagattt aatagaagaa aatatggatg
     4741 aattagtgaa taatctaagt aaacaaggtc atattggagc aagagaagct attatgacaa
     4801 ctgatattat aaaaaaagaa atagcagtag caataatgta tggagataaa aaaataacta
     4861 ttggaggtat ggcaaaaggt tctggcatga tacatcctaa tatggcaaca acgttaggat
     4921 ttataactac agatgcaaat attgatggag ttttgctaaa agaagcttta aaaattgctg
     4981 ttgacaaaag ttttaataga gttagtgtag atggagatac aagtactaat gatatggtaa
     5041 tgattctagc aaatggaaaa gcaaaaaatg atagaataaa caaaaaagat gaacattatc
     5101 aagtattttt gagtgcactt acatatgtct gtatagaact tgctaaactt gttgcaaaag
     5161 atggagaagg atgtacaaaa ctaattgaat gctatataaa tggagcatta agtgaagaac
     5221 atgcagtaaa attagcaaaa acagttatat cttcttcatt agtaaagaca gctgtatttg
     5281 gagctgacgc aaattggggt agaatactgt gtgctttagg ttatgcaggt gaagaaatag
     5341 atatggaaaa agttgatatt atttttgaga gtatgaaagg atatattgaa gtatgtaaaa
     5401 atggaaatgg attagatttt aatgaggaaa aagcaaaaaa aatccttgaa gatgacgaaa
     5461 taagtatatt agtagattta aatatgggca atgccagagg aaatgcatgg ggatgtgatt
     5521 taagctatga ttatgtaaga ataaatggaa gttatagaaa ttaggaggat atactttaat
     5581 gattaatata gaaaaagcaa atacacttat agaagcttta ccatatatag aaaaacatca
     5641 gggaaagact attgtagtta agtatggtgg aagtgcaatg aaaaaagatg gtctaaaaga
     5701 atctgttatg gaagaccttg tgttaatgag ttatgttgga atcaatatag ttttagtaca
     5761 tggtggaggg gcagaaatca ataagatgct agcaaaagtg gatatagaaa gtaaatttgt
     5821 aaatggtctt agatatacag atgaagagac catggaaatt gtaaaaatgg tacttgctgg
     5881 aaaggttaat aaagacttag taaataaaat acatacaaaa ggtggaaaag cagtagggct
     5941 ttgtggaata gataataata tgattttatg tgacccatat aaaaattatg aacttggatt
     6001 tgtaggagaa atcaaaaaag taaatgttga gcttatagaa tcttgtctaa agtcaggtta
     6061 tatttcagta attgcaacta taggtgttgg agatgatgga gagacttata atataaatgg
     6121 tgacacagca gcttctgcta tagctaaaga gttaaatgca gataaattga tacttcttac
     6181 agatgtccct ggtttgttaa gagagccaga tgaagaaaaa tcattaataa cagaagttat
     6241 attagaggat gttgataaat tatttgaaga aggtataatt actggaggta tgatacctaa
     6301 aatagaggga tgcgtagatg ccttaaataa cggagtaaat agggtacata ttttggatgg
     6361 aagagttcca cattctataa taacagagct atttactgat agtggaatag gtacattaat
     6421 aagaaaagaa actgaataaa attataagtt taagagggga gaataagaat gaataacgac
     6481 aatacaattt caaaatggaa tgaatatttt atagatacat ataaccaacc caattttgtc
     6541 atagattatg gtgaaggaag ttgttttttt gatactaatg gcaataaata tatagatttt
     6601 acaagtggat atggagtatc ttctcttggg tatagtaata gtaatttaaa gaatgctcta
     6661 aaagagcaag tagataaatt attacatact tcaaatttat attttaatga gccagtgttg
     6721 tattcaggag agaaaataat taattcaagt ggaatggcta aagtatattt ttgtaattct
     6781 ggaacagaag caaatgaaac agcattcaaa atagcaagaa agtatagtag tgacaaatat
     6841 ggtaatggta gaggaactat cataagttta aaagactctt ttcatggtag aacaatgatg
     6901 tctttaatgg caactggtat ggacaaatac cataagtatt tttatcctct tcccgaaggt
     6961 tttaaatata tagaaagaaa taatattgaa gatttaaaaa ataatcttga ttccacagtt
     7021 tgtgcaataa ttcttgaagc gattcaaggc gaaggtggag ttaatgttct tgaaaaagat
     7081 tatgttttgg aaatagtaaa aatatgtcaa gaaaaggata ttgtagtgat ttttgatgaa
     7141 gtccaatgcg gtataggaag aactggtaaa ctttttggct atgaatattt tgatgtaaaa
     7201 ccagatatag ttaccgtagc aaaagggttg ggagcaggaa taccagtagg aggagtattg
     7261 gtaaataaaa aactttcaaa agtactagga aaaggagacc aaggtacaac ttttggaggt
     7321 aatttattag ctatggtggc agcttcagtt gtattagatg agatatctaa agatggcttt
     7381 tataatgaag tattagaaaa aggaaattat ataagaaaat ctattgaaag ttttaataac
     7441 aaagttatat taaagacaaa aggtattggt ctaatgatag gaattgaaac taatattgaa
     7501 tctagtatta tagaagagaa agctagaaaa aaaggattgc ttattttgac tgctggaaaa
     7561 aatgtattga gatttttacc accattaaca atcagttata aggaaataga tgaggctctt
     7621 gaaatcctaa aagatatatt actagaaatt aactaaatat tcaaaaaata gttgattaaa
     7681 gataaaaatt agaagtaaat aaaaaagtaa agtgctaaca agtttaattg aatttaaaaa
     7741 gtttataaga aggggcgaat taatatgaat aatataagtt taaaaggtaa gagttttttg
     7801 acattaaagg attttacaaa agaagagatt agatatttat taactttatc aagttattta
     7861 aaaactaaga aaaaagttgg tataaaaggc gatttgctac aaggaaaaaa tatagcttta
     7921 ttatttgaga aaacatcaac aagaactaga tgttcatttg aagtagcagc tcatgatgaa
     7981 ggagcacatg taacttatct aggtccaaat gattgtcata tgggtaaaaa agagtctgta
     8041 tcagatacag caaaagttct aggaagattc tatgatggaa tagaatttag aggctttaaa
     8101 caagaaacag ttgaaagtct agcaaaatat tctggtgtac ctgtttggaa tggacttaca
     8161 gatgaatatc atccaacaca aatactggca gattttttaa cagtaattga aaatgtagat
     8221 aaagatttga ataaagttaa atttgtatat gttggtgatg ctagaaataa tatggggaac
     8281 tcactgatga taggatgtgc taaaatggga atacatttcg tagcactagc acctaaggaa
     8341 ctttggccaa atgaagaatt ggttaaggaa atgaaggaaa tagccaagaa atccaaagga
     8401 gatataatgt tgactgaaaa tattgatgat gttaaaggtg cagatgttat atatacagat
     8461 gtatgggttt ctatgggaga agaggagcaa tatgaagcaa gaataaatca acttaaagat
     8521 tatcaagtaa atatggatat gataaagaaa actgaaaatg aaaatgttat atttttacac
     8581 tgtcttccag catttcatga tttagaaact aaggttgctc aggagattta tgaaaagttc
     8641 ggattatcag aattagaggt tacaaacgag gtatttaatt caaaatattc aaaggtattt
     8701 gaagaagctg aaaatagaat gcatacaata aaagctgtta tggtttctac tatgactgat
     8761 gtaaatatga acaataattt aatatagata tgttttaata tagactttac tttaatgaaa
     8821 atttataaaa tattttaaat atattattca aaaactctca ttatatgtta aaataactta
     8881 tgtatcaaca aattaagagg gaggatttga gatatgaaaa aaatcatatt agctttaaca
     8941 acttttttat tagcaatatc tttaacagca tgttcaagtg caaaaccaga agatacaatt
     9001 gatagttttt ttaacagtgc gaaaaagttt gactttgaag gcatgaataa ggtaatggaa
     9061 aataatgacg aaaaatataa ggatatatta aaggaattag atacaaaaga cccaaatgcc
     9121 caatatgttt tagattatct aaaacagaat gcatctaaaa tcacatatac aataaaagac
     9181 agcgaggtta aaggtgataa ggctacaatc aaagtagaat gtaaatttat agattcaaca
     9241 ccattacttc aagaaatagt agctgaggca tttacaaaga tgattggtat gagtttttca
     9301 ggacaagact taactgatga gaaaacaact gaaatgttag tatcaattat gaaagaaaaa
     9361 caaaaaagcg ttaaagagac ttatgttaca aaaaatgtag agtttgaatg ttctaaaaag
     9421 gataataaat ggataataag ttcagtaaat gatgcagtag ctgatgtatt gttatctaat
     9481 cttgttacag caggacaaga attttctaac tctatgaata cacttgaata atattgttta
     9541 ggtgtagtaa agtaataaat atatgattat ttttataaat aaacatataa atatttatga
     9601 aggataccat ttttggtatc ctttttatta atataatgaa atacatggtt aatttctata
     9661 ttgtcaagaa actatgatat atgttataag tctatactat ttaaaataaa cttataacat
     9721 atatttttta taatatagtg tatgaaaaat ttatttaact aattttagat atttattgac
     9781 aactgattca gccaagcatt ttgatgaatc aacaatattt attgaaggat atgatttttc
     9841 taaaactaca tttaaatcag tacaagcaat tactatattt tctatagatt catttttaac
     9901 atcttcaata agtttattcc aaatatcaat attgtgtgga ttttctttat ccatttttat
     9961 attttgaata agattgttta attttatttg ccattcatct ttaaatataa attcatgtcc
    10021 attatgtatt ataccattct ggtaaattgt agactcaaaa gttgaactag tcgaaaaaag
    10081 agttactttt tgtgagatag taggtaattt tttaactgtt tcttctacaa tatttaatat
    10141 tggtatatta atagactctt ttaattcttt aaagtatata tgtgctgaat tgcatggcat
    10201 tgcaataaaa tttacaccag ttgattcaag cttttgtaat ccatcaatta tagtttcttt
    10261 cataaggtca tgatttattg gacggtcaat ataaaatggg gtaggtaatg aatatatcat
    10321 catctttgga aattcatcat catattttgc tccatattga gattgacact catcaataat
    10381 taaatcaaca aaaggggctg ttgaccttgg acccattcca gccaaaatac caattaattt
    10441 ttcattcata aaaattat
//
LOCUS       DAYAKB010000109        10317 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.110, whole genome shotgun sequence.
ACCESSION   DAYAKB010000109 DAYAKB010000000
VERSION     DAYAKB010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.110"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            176..1075
                     /locus_tag="ACGI3L_003363"
     CDS             176..1075
                     /locus_tag="ACGI3L_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9199057.1"
                     /translation="MSIVLNMPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKN
                     NKINFEAVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLV
                     GNYIAERYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVN
                     QKLSEWTSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLF
                     RYGGDEFLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDI
                     ETLISKADSLMYENKLKNKSTLN"
     gene            1284..1433
                     /locus_tag="ACGI3L_003364"
     CDS             1284..1433
                     /locus_tag="ACGI3L_003364"
                     /inference="COORDINATES: protein motif:HMM:NF012772.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9199058.1"
                     /translation="MTTVAEGIETSFQKDFLQEINCDMLQGYVFSRPLPIKDFEKLMF
                     QNSSN"
     gene            complement(1693..4260)
                     /locus_tag="ACGI3L_003365"
     CDS             complement(1693..4260)
                     /locus_tag="ACGI3L_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HFG9199059.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYMSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(4263..4868)
                     /locus_tag="ACGI3L_003366"
     CDS             complement(4263..4868)
                     /locus_tag="ACGI3L_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9199060.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLNGIMNDGGE"
     gene            complement(5242..6702)
                     /locus_tag="ACGI3L_003367"
     CDS             complement(5242..6702)
                     /locus_tag="ACGI3L_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HFG9199061.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRGNIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            7064..7642
                     /locus_tag="ACGI3L_003368"
     CDS             7064..7642
                     /locus_tag="ACGI3L_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9199062.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            7933..9183
                     /locus_tag="ACGI3L_003369"
     CDS             7933..9183
                     /locus_tag="ACGI3L_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9199063.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            9344..9913
                     /locus_tag="ACGI3L_003370"
     CDS             9344..9913
                     /locus_tag="ACGI3L_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFG9199064.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3466 a         1762 c         1483 g         3606 t
ORIGIN      
        1 ttttattatt tgtacttatt taaagtttca tctaattata aattggacaa tttttatgtt
       61 gattttattc atacaaatta aagtaactta taaaatctcc acaataaaaa acatttttta
      121 ttcactaaac tgctccatca ttggtttagc aataaatata ttttttaggt ctttaatgtc
      181 aatagtgtta aatatgccag catatttatt tgatagtaat tctattgcaa atatttacag
      241 agtatttcct atatcattta gctttatagt tacaggacta tatttcagtt ataaaaataa
      301 taaaaataat aagattaact ttgaggcagt tttagaggac aaaaaaaact taattttctt
      361 attgagcctt atgtttggaa tgtacttgta tctatgtttg agtttgtcaa tatactatac
      421 tgttggaaat gtattgattt taaaattata tggaatcaag tctgccataa tagttttggt
      481 aggtaactat attgcagaaa gatatagctt tagaattact caaataaaag gttatgatat
      541 taaaaatcaa atagaatatg tagaaagtgt aaagacagaa tatgagatta ataaattgaa
      601 tgatattgta tatacagatt tactgacagg tttctacaat agaccttttg tgaatcaaaa
      661 actatcagaa tggacatcaa atcactacaa atttacctta tgttttactg atttaaatag
      721 cttaaaacct gtaaatgata aatttggaca ccaatttggt gataaataca tatccactac
      781 tgctcaaata ataaaaaaac ttataaatgt agaaaattcc ttactattta gatatggtgg
      841 agatgaattt ttattccttt tacagaatac aagttgtgta gaagcagaaa agataatgat
      901 taatataaat tatgaattat caaaattaag taatactgac gagtatcctt atgctctttc
      961 cataagctat ggattagttg agtgggatgg aatatccgat attgaaactt taatatcaaa
     1021 ggcagattct ttgatgtatg aaaataagct taaaaataaa tctactttaa actagctagt
     1081 taagatattc tacaaaatat atgttataag agagtactaa gaatatcaaa atatatagat
     1141 tttgcaaata ttgaatacag tttactaatg aatgcactgg atgtaagtgt tagtaaacac
     1201 ctattagatg aacactttac tgttgtttgg gctaatgacc gttattatga aatgttcagc
     1261 tatacctagc taaaaagtta aaaatgacca ctgtagccga gggaatagag accagttttc
     1321 aaaaagattt cttgcaagaa ataaactgtg atatgttaca aggatacgtg ttctctagac
     1381 ctttaccaat aaaagacttt gaaaaactta tgtttcaaaa ctcctccaat taacaatata
     1441 aaattgctta ttataagtga tattattgta tcaacaaata aaggaattgt ctcaaaattg
     1501 attttttcta atcaaatttt tattttgaga cattctcatt tttttgcata agaaaatacc
     1561 caccaagcta cggtttttct taccgctgtt cggtgggtat tagtagtatt atgaaatctg
     1621 aaaactttaa gtattactac ttccgctaac gcaatcacaa aggtcgaaag cttcaaagcg
     1681 aaaataggct ttttactcat caaacgtcac cgtacctgcc aacccgtcca ccgttatcat
     1741 ttgtccgctc ttaatagttc gtgtggcaat gtgtgtagcc ataacggctg ggatgccata
     1801 ttcacgtgcg acaatgcttg aatggctaag aggaccacca atgtccgtta caatcgcact
     1861 tgcagatgaa aataatggtg tccatgctgg agttgtggta actgcaacca aaacacttcc
     1921 aggttgaaag ctttcaaaat ctgctggact attcagtaca caagctggag ccgtcacaac
     1981 accagtactg gtaccaatgc ccgtcaacac aattttccca tctttctgct tctgttgtgc
     2041 ttgtgatata gtttttttgt ttttctctgg caacttggat ggtgacatat aacccatgta
     2101 ttttttaagt tcagcttttc gaacaggtat tatcccgttc atatcagata gagacttgtt
     2161 tttatccaac tgctctataa gtacctccaa ttccgatttt gtgagccaat aaatatcatc
     2221 taaatgtgaa atagctcctc ctcgtatgaa tcgttctgag atttcctgaa acatacaacg
     2281 aatcagagga tgtcccattc ccatcaaata aatagcattt tcacgcatag gagaggtttc
     2341 ctgtgcccaa tggagcaact taaaaaatag ttttttacgc aatccaccta tgtgttgtaa
     2401 aatctcttct tctgcatgtt ttctacgctt ttcaaacgtg gtctggcgta aaaaaggact
     2461 ttcccctttt ccttccacaa atgtttttac ggattcaaaa gttggtgtaa gtgtttcctg
     2521 cggtgtggaa tgcgcaaaat caaactcata agcggtacga ccaaactctt taaagtactt
     2581 attgattcga tttttccatt ctatccatac ttcctgtgaa actccaacag gcacaactga
     2641 agacatgaaa tcttctgcta tctttattgc aggactgttt tgcagataaa ggttgatgct
     2701 gttattttgc tttacccatt ctgaaatacc ccacaactcc ttttccgatt gcagaacaat
     2761 cgtatcaaac ccaagcagga aaacggaagt atccgttata ccagcacgtc gaactgctcc
     2821 ttgaaataat tttgtaaata atgtttcact gatagaagca gcaggcaatg taagctgaat
     2881 ccttgtgaaa taaatacatg cggcataaaa tattgtctga ataccctcca taatttgatg
     2941 ggcgttcata gtatgcaggg gcttttcttc ccattgttta atagcatcct catatccttt
     3001 tcgtgccgtt tcccagcgtg caacgctgtt cataagtgtc ctacgtaaag agcgtgggga
     3061 aagggatttg atagcaatca aaagtggctt tgatttagca gaaagataaa catatccatt
     3121 aataaccgta tatgccccgt tttttggtaa taattttttc gcacttttac caaacatatc
     3181 tatccataaa agctctgatg cacggtttac gatttcaaga ccaagtgtgg cgaacaaagg
     3241 tgtaacagga tttggcaaat gttctgccaa acttcccttt gtgtatacaa catcctgttc
     3301 tggcaatacc cattctggtg gcagaacagt aattggacga gcctgaacaa tgtacaattt
     3361 atctttttcc agtgcccact ctacatccat aggcatttga taatacttct caattttctt
     3421 tccaagctgt atcagttgca ttacctgatt acgagtaaga gcatattttt ttctcaacct
     3481 ttcaggaacc atggtttctt ctgttccttc tgaagtacga accgtcataa tctctttatt
     3541 tgccacttca tacgatataa ttcgttcgga gtccttatcc actacgattg tatcgggtgt
     3601 aactaagcta gaaaccaccg cttcaccaag cccccatgca gcgttaataa tcatttcgct
     3661 acgtctacca ttgattgggt ttaacgtaaa cataatacca gatgaatcgg aaaatgcaag
     3721 cttttgtact acaacagcaa gtgcgacaat ctcgtgcttt atattattct tcacacgata
     3781 agcaatagca cgagctgtcc ataaggaagc ccagcatctc tttacagagt caataacttt
     3841 atcttcacct tgtatgttaa gataagtttc ctgctgacct gcaaaagaag cgtcaggtaa
     3901 atcttcagca gtcgcagacg aacggacagc caccgatatg ttccctaatc cagcataagc
     3961 cattttaatt gcgtccgaca cttcctgtgg catttctcca ttatggaaaa gctcccctat
     4021 tttcttagat acatcttcaa gttggctggt attattggaa tcaataccat ctagcagttt
     4081 attaattcga gactgaatat ggttcgtctc aacaaaaatc tggtatgaag cagtcgtaac
     4141 atgaaaaccg tctggcacag ggatgcctgc tgtcaatagt tttgataaag acatcccttt
     4201 tccaccaaca atttcaatgg ttgcttgttt atgttccagt ggcaagacat aataaatcat
     4261 aatcattcac ctccatcatt cataattccg ttcagaaata tattcattgt ttcatccaac
     4321 attttttccg aactatccaa tggtcgtgac gtgtagctga ttgataacat ggagttaatt
     4381 aacaaacgtg tcacaagagc ggtatccgtt ttgcgaaaga tgcctgtggt cacaccatta
     4441 tcaattaccg attttataat atcttgatat gcataacgag catctttaag tctctttcga
     4501 tactcttctt ctaaataatc agattctgta tttaaccaca tcagtacagt tctatactgc
     4561 tctggaaatc taagatgatt aagcatgatt tttctaaggc actgttgtgg tgaaggttca
     4621 ccatcaataa tcctatgaac ttgttggata gttttttcta tttctttctc aactgcatat
     4681 acaacaatct cgtctttcgt tttaaaaaaa tcgtatagac ttgactttcc catgttggct
     4741 aaaactgcaa tttctctcat tgatgttttt tggaatccat tttcagccat gagactcaaa
     4801 gcaacagcaa ctattttttc tcggcgttct gcttgttgtt cgggtgtaag cacaattcct
     4861 tttggcatag tgcgatacct ccttttagcg accactggtc gtttcttttt tatttatcat
     4921 acagcaacca acggtcactt gtcaaggtta atttttttca ttgtatatgg tactcgagat
     4981 aaaaatgttc attttagaaa ttactctatt taagtagaaa taggcttcat cattagaaag
     5041 caagactata aatttgagat atttatcatg ttcaaatttc atcaatatca aagtttaaaa
     5101 tattaataaa aaaagaatta ctaagaaata acatataaag attcaaaaaa ggagttgaac
     5161 ttaaaattca attacaaaaa atcaaattta agacaactcc tttattcttt atctctacta
     5221 ttctttatct ctatttattt attacaactc cctaacattt accactactg ccttaggtct
     5281 agtcatagcc tcaattgaat acttaacacc ttgagttccc ataccagatg cctttacacc
     5341 taaaaatggg aagtggtctg gacctctttc agtcttatta tttatttgaa cagtaccaac
     5401 ttcaagttta tcagctatat aaaatgcctt atcaatatca cttgtaaata ctgatgattg
     5461 aagcccatac tctgattgat tagcaatttc aattgcttga tttatatctt taactcttat
     5521 aattggaagt actggaccaa atggttcttc ccaagcaatt ttcatatcaa catttacatt
     5581 atctaacaat gttggataga ataaattatt ttttctaaca ttgcctgtta ttaactttgc
     5641 tcctttatgt aatgcatcat caaccaaccc ttgaacaaaa tcagttgctt tattatctat
     5701 aagaggagtg ataactactt catccattgg atttccaatt gtcaacttct ctaccaatgg
     5761 ctttattttt ccgactaatt tatccgccac actctcttgt actaaaattc tctttactgc
     5821 cgtacatctt tgtcctgaat atgaatacgc tccagatact atattcttag ctgcaaaatc
     5881 taagtctgca tcttctaata ctatagccgc atcttttcca ccaagctcca ataataatgg
     5941 taccattcca gatattttag atatatgctg accaacttca gtactaccag taaagttaat
     6001 aaaattaatt cctttatgcg ttacaacata atcccctatc tcactacccc tacctgtaat
     6061 agtattaagt actccatctg gtatcccagc ttttctcata atttctacca catgaagtgc
     6121 gctaatagcc ccttgtgtag caggttttaa tacgactgca tttccaccaa taagtgctgg
     6181 agcaatcttt gacattgata aatttacagg ataattaaaa ggagatatag ctaaaacagt
     6241 acctaatgga acccttgaaa cataagacat cttatttctt gttccaccag ggaaattatc
     6301 tccactaatg gcttctccct ccatattttt tcccacatca gctgtgtatc ttaaaaaatc
     6361 tgctgttctc tcaacttctg cccttgcaga ttttatgtct ttggctattt caagtaccag
     6421 tatattagct atctcatcta tattttctaa caataaatca gcagccttat gaaatatatt
     6481 gcctctcttg tatacaggca tttcagccca tacttttata ctctcttttg tgttttttat
     6541 aacctcatct acctcatgtt ttgtcataga ttgtactttc ccaacaagag aattatctat
     6601 tggtgagtaa atttctattg gctttctcga attagattct acccattttc catttattaa
     6661 atttttatat acattttctt ttgttttaag ttcattaaac atatttttat tcctctctct
     6721 gatataactt tgtgtattta aattatagcc atttattcgt tatgtaaaca tttctttttt
     6781 tcataaacgt ttacctataa aaaaatttta agttaacgtt tttctacatt cttctatttt
     6841 aataacatac tcgctccaaa tctatatagg tcacacttta atactaatat atcaatatac
     6901 caatatacca atataccaat ataccaatat accaatatac caatataaat attataaaca
     6961 taaatcactt gacaaattta taagtagaca atattatata tctatgactc aaaatatttt
     7021 taaagtcata tatatcatat atagacagaa aggattgata aaaatggcta aaagttttac
     7081 agaaatagaa aaagacaata taagaaaaag actaatttca gaatgtgaaa tcaactggtc
     7141 taaatatgga tacaaaaaaa ctaatattga tgaactttgt tcaaaatcag gaattgcaaa
     7201 gggttctttc tatacatttt ttgattcaaa agaaaagtta ttttttgaag tattaaatgg
     7261 aatccaaaac agacttatat catcagtaga tgaaatttta agtaacatgc ctccaaaaga
     7321 aggctttgca aaatccttaa aaatgttata tcgattatat gataaaaatc catttttata
     7381 ttcaccaaat aatcctgatt tcatcagcct aataaataaa ctacctcaag atatgttttt
     7441 acaacttgag tccaataaca tacaaagttt ttacgactta attgagagac acaatctcaa
     7501 gttgaagata gaaaaagaaa aagtttttgg tgtttgtaat gctctactat caagtctgtt
     7561 ggtaaaagaa aatattgaat ataactatat tgaagtgttt gactttatgg tggataatct
     7621 tgtagaacac atacttgaat aacaatttaa aataattttt ctaagtattt ttttatacta
     7681 aataggatta atatgattga attaatgcaa aaaataaaca atataattta taaaataaat
     7741 gataaactaa atatcacaca aaacttatag accctagagc aaacccattc cactctactc
     7801 taagccatct ataatagttt gtatatttct aataatatta gatattaaag taagaaaaaa
     7861 attccttata ataattgcta ttatatcaat tattgtaaat gttttaataa tcttagatag
     7921 gtaggtacat atatggtaaa atcctcgaac acttttaata aaaacttcaa cttgatgata
     7981 ttaggtcaaa taatctcatt gtttggtgca tcaatactta aatttgcttt atctttatac
     8041 atacttgata taactggtaa agcagaaata tttgctacta tactagcagt atcttcaatc
     8101 ccaattatag tattctcccc tattggtgga gctattgcag atatattcaa cagaagaaac
     8161 ttaatggtta tttttgattt ttcaagtagt cttacagtac taatcttagc agtattctta
     8221 ttcaacaata atggttcaat attacttgta ggaattatta tgaccatatt atcagtcata
     8281 agcacaatgt atcaaccaac tgttcagtca agtacacccc ttttagttga taatgagcat
     8341 ttaatgaatg caaatggtat tgtagctgga gttgcatctc ttacaaatat tgcaggacct
     8401 gtattaggag gtgtcttgta tggtgtgatt ggaattaatg caattatagt tataagttgt
     8461 gtaagtttct ttctatctgc aattatggag atatttatac agattccttt tatcaaacaa
     8521 gagcaaaaca gcaacattat aaaaactata tttactgata taaaggatgg tattgttcat
     8581 atatgtaaag aaaatagatt tatactaaaa atactttttt tagctatagc aataaactta
     8641 tttttaagct ctatgttaat agttggtatc ccctatatag taaaaatcac tatgggagct
     8701 agtaacttct tatatggtct agcagaagga gcaatttctt ttagttcact ggtagctgct
     8761 gttagtattg gtattttctc aaaacatcta aaaatcacta atttgcatat ttcctttatt
     8821 atatgtgcag ttatgttcat accaatggcg gtttcagtat atccatttat attaaacaca
     8881 ggatttccag ttccattttt aatctttata gtatcatcta tgctaatatt ttttacaacg
     8941 actcttatct caatatatgt tataacagtc acacaattaa aaactccaaa tgaactctta
     9001 ggaaaagtaa tgtcaattct ttttgcagga acagcaattg caatgcccct tggtcaggtt
     9061 atgtatggta aactttttga tttattatca gatagagtgt acatcattat actaggagtt
     9121 ggatttatta cattacttat agcatttgta tcaaagataa cattgaggaa cgaaaatctt
     9181 tagatacaaa gaatttagat ataaagattt aattttcact aatttctgaa tttaaatgca
     9241 aaattgtgta tcagtatgtt gacgttttag aaattgattg atataatcaa tggaaaataa
     9301 actttataaa aattcaaaat attcagctag aggagtgata aaaatgagtt acatgccaac
     9361 tttagaacaa gcatgggaaa tattaagaaa atacaataag gaagaatttc atataagaca
     9421 tgctcaaatt gtatctggag ttatgagata ctatgcaaag gagtacgacc ctgaaagagt
     9481 agaattttgg gaaatagttg gacttttaca tgatttagat tttgaaatgt atcctgatga
     9541 acattgtgtt aaacaaagag aattaatgac agagcttgat ttagataaat caataatcga
     9601 ttctacaata agtcatggat atggattaac tggttcagat gttaaaccag agcaatttat
     9661 ggagaaagta ttatttgctg tggatgaact tactggttta attggtgctg ctgcaataat
     9721 gcgtccttca aagagcgttt ctgatttaga attaaaatct gttaagaaga aatttaaaga
     9781 taaatcattt gctgctggct gttctcgaga cgttataaga agtggtgcag aaatgcttgg
     9841 atgggaactt gataagctta tccaaacaac tatagaagct atgagaagct tgattccaga
     9901 gatggcaata tagctcctcc atacatatac catagaagtt acatctttaa agagcatttc
     9961 tctttttgat gcaacttctt tttatatttt gtagaataaa aagtttaata ttttaaactc
    10021 actatataat aaataatata atgtataata gtcataaact ttctaacctt aaaagtttct
    10081 aataatcaat aaacaattct aatatacaaa tgtcattata tgatttaatt atatatcttc
    10141 aatttatata ttaaaataaa tatatatata ttaaattctt atacaccaaa tttttacatt
    10201 aaacttctat gcaccacatt tatacatatt aaattcttat atattaaatt tctatgcatc
    10261 acttttatac atattaaatt cctatatatt aaacttttat gcatcacttt tatacat
//
LOCUS       DAYAKB010000110        10113 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.111, whole genome shotgun sequence.
ACCESSION   DAYAKB010000110 DAYAKB010000000
VERSION     DAYAKB010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.111"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1131
                     /locus_tag="ACGI3L_003371"
     CDS             <1..1131
                     /locus_tag="ACGI3L_003371"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9199065.1"
                     /translation="FVNYFDDESDKKYIINLIDIMNKNQIFKSNNLNFDMLSNGVAIY
                     FCLTNRCNLFCKHCCVESSSNKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIRED
                     FFEIIKYIKQKLPDTKLILSTNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRG
                     KGVFNKVISSVNLLKDNGFSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPT
                     GRGLENKESYLIEDTVLPITIPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDG
                     DVYPCPSLIKDDYKMGNIFDNEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVN
                     IFCWHCPAILDSVKDNELELDRWCSMMKHNLNTAVWGDEKVN"
     gene            1128..2144
                     /locus_tag="ACGI3L_003372"
     CDS             1128..2144
                     /locus_tag="ACGI3L_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9199066.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            2200..2361
                     /locus_tag="ACGI3L_003373"
     CDS             2200..2361
                     /locus_tag="ACGI3L_003373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199067.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            2569..5115
                     /locus_tag="ACGI3L_003374"
     CDS             2569..5115
                     /locus_tag="ACGI3L_003374"
                     /inference="COORDINATES: protein motif:HMM:NF014717.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9199068.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            5157..6401
                     /locus_tag="ACGI3L_003375"
     CDS             5157..6401
                     /locus_tag="ACGI3L_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9199069.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            6449..7438
                     /locus_tag="ACGI3L_003376"
     CDS             6449..7438
                     /locus_tag="ACGI3L_003376"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFG9199070.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            7475..8149
                     /locus_tag="ACGI3L_003377"
     CDS             7475..8149
                     /locus_tag="ACGI3L_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199071.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            8133..9875
                     /locus_tag="ACGI3L_003378"
     CDS             8133..9875
                     /locus_tag="ACGI3L_003378"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199072.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
BASE COUNT         4289 a          842 c         1629 g         3353 t
ORIGIN      
        1 tttgtaaatt attttgatga tgaaagtgac aaaaaatata ttattaatct tatagatatt
       61 atgaacaaaa atcaaatttt taaaagtaac aatttaaact ttgatatgtt aagcaatggt
      121 gttgcaattt atttttgttt gacaaataga tgcaatttat tttgtaaaca ttgttgtgtt
      181 gaatcttctt ctaataagaa agatttactt agtacatatg atttaaaaaa tatcgtagat
      241 ataatatcag ttttaaatac tcctcatata attataactg gtggagaacc attgataaga
      301 gaagattttt ttgaaataat taaatatata aaacaaaaat tacctgatac caaattaata
      361 ttatccacaa atggaacttt aatagatgaa cataatgttg attttattat aactaatttt
      421 gaaaaaatag atattagtat tgatggagta gatgaaaata cttgtagtga aacacgagga
      481 aaaggtgtat ttaataaagt aataagctct gttaatctgc taaaagacaa tggattcagt
      541 aatataaagc tgtctatggt atttggacaa aaaaattctc atttaaataa acaatttaaa
      601 gatttaaata aaaagcttgg aacagaattt gttgaaagat attttattcc aacaggaaga
      661 ggcctagaaa ataaagaaag ctatttaatt gaagatacag ttcttccaat tacaattccg
      721 tatattttag ataatgaatt aaaaatgtgt aaagataaaa aaaataaaaa aatgggatgt
      781 tgtgcatgta atgcaggaaa ctctcaaata tttataaatt atgatggaga tgtatatcct
      841 tgtccttcac tgataaagga tgactataaa atgggaaata tatttgacaa tgaatttgta
      901 aaagttataa aagaaaataa aacaagagat ctaaagtctt tgattaaatt agaaagtatt
      961 tatccatata actttgaaaa atgtaaagat tgtgatgtaa atattttttg ttggcattgc
     1021 ccagcgatat tagattcagt taaggataat gaattggaat tggatagatg gtgtagtatg
     1081 atgaaacaca atttaaatac agctgtatgg ggagatgaaa aagttaattg aaatttacta
     1141 tatttgtaac tgaagactgc aatttgagat gtacatattg ttatgaaggt aatgataaaa
     1201 aaaaagaaaa tatgagttat gaaactgctg ataaaacaat agattttatt tgtaataaag
     1261 aattagaaag taatagtgat tatacaacaa ttgttttaca tggaggagaa ccatttataa
     1321 attttgattt gattaaatat atacataggg atttagtaga tagattgagt gacaaaaaga
     1381 tattatttga tataactaca aatggaacta ttataaatga tgaaataata gagtttatag
     1441 caaagaatgt aaaaaacata tcgataagta ttgatggaaa aaagaatata catgatataa
     1501 atagaataga tgctaacgga gtaggtactt atgaaaaagt aatggaaaat ggaaaaagac
     1561 ttatagataa aggtatatat gttagggcaa gaatgacata taactcaaat actgttaagt
     1621 atctttatga gagtgtatat gatatagcaa aacaagggtt taaaaatatc gcaccaattt
     1681 cagattttat ggataaaaat tgggataatt ctcatattaa aatattaaat gaacaaatta
     1741 gtaaaattat gaatattaaa aaggattatc ctgatataga tatatctatt ttagataaac
     1801 aatttataaa taagaaaaaa ggagattgtt ttggagggat aaatagttat gcaatagata
     1861 ctagaggaga tgtatatcca tgtacagtat gtgtaggaga taaagatatt ttactaggaa
     1921 atatatatga tggattagat gataaaaaaa ttaagaacct tataaaaatt tatatatcta
     1981 agaatgaaga gtgtgatgga tgtactagac ttgattattg tatgtcaacc agatgtaaac
     2041 ttatcaataa aaaggtaaca ggtaaattcc aaagtgcagt accaatttat tgtggattag
     2101 aaagagttta tgtggaaaca acaaaaaaac tatgtagttt ataatctagt ttaactagtt
     2161 ataataaata taaaacaaaa gtaaaggggg atatgtatta tgatacatat aaaaaaaatc
     2221 gaagaaaaaa tagaacttca agatgttgag gtgcaagcag atccatgtaa atggtattat
     2281 gataagcatg gaataatttc acaaatagac tgtatggtgg attgtgcagg atcaactcca
     2341 aaaggaacag tagcttatta aaaaatacta atcagtctat taaatatgtt gaaagtacta
     2401 gatgtagttt tttacaaatg aaatgtgatt ttctcaactc tagtattttt aataattaaa
     2461 tttaactagc acaacgagtt agttagtatt taatgaatag tgctctataa cctactattt
     2521 taggttatag agtttttctt gtaaatatga ataaggagga ttctgattat gataaatatt
     2581 aaacttgcgg tgtcatattt aaagagacaa aaaggaaaaa ctttatcatt aatacttagt
     2641 atagggattg ctgttatgct agttttttca ttaagtgtta ttaatgaatc tcaaggacaa
     2701 tcagatataa atcatgcata caaaaactcg ggagattatc atgcttttta tgaagatata
     2761 aatagtgata tagtaaaaga acttaatggt gaagaagata taaaagaatt caatgatgta
     2821 cttaaatttg gagaaattat aagtaaagat aatggagcat ctctaaattt atgctcttac
     2881 aataaagatt ttttagattc tactagatat aagttagtta aaggtagaga gcctagaact
     2941 tctaatgaat tagtaataga acaaaaagtt ttagacaaaa tggaattaga tgtcaaatta
     3001 aatcaaacta ttgattttca gattgttaat gagcatataa ataaaaataa tgaaaattct
     3061 atttatagta aagataagca atttaaaata gttggtattt taagtaaatc tgatgaatac
     3121 tatgaaaatt taaataaata taaggtaaga gcttttacat attcaaacaa tggcaaagat
     3181 attgttccat atgaattaat aactcatatg ggtacattaa aattgaatac aaaagattta
     3241 gattctcaaa aagtagtgaa tctagggaga aaatataagt taacaagtaa tcaattttat
     3301 ccaaatacag aagtaagtat gtctatgtat atgaaaaata tttcaaaaaa aacaacttat
     3361 tcaataaagc aaagcttact ccctttatta tgtgcaacat tagtaatata caatatgttt
     3421 aacataataa tactagatat gaccaagcaa attggtttac ttagagctgt tggagctagc
     3481 aagagaaata ttagacaggt attttttatt cagagtattg tagttttatc tgtaggtata
     3541 gtaattggtt tacttggagg tatagttttt tcttacttag gtctcatgat agtatatgat
     3601 aaaagtgcag aattaactat aaatacaaac tctataattg aatctatcat catgtcaatt
     3661 atagcagtta tattagcctc tgtagtacca atatataaag ctggaaattt atctataatt
     3721 gatgctataa aaaagacaga taagttaaat tatattccta ggcttttgtt gttaaaatca
     3781 cataaaaaag ttgttggaat tataaatgag atagctttta aaaatatatt taggaataag
     3841 gttacatcaa taataataat aattacgata tcactatgtg gggttttatt tataggcaga
     3901 ctaacttcta caaaattcat atatggaaaa gagtcagatt cagctaatat aacaagtaaa
     3961 tcatatggca attttgatat ttatttggga tattcaccaa taaatgcaaa ttatacattt
     4021 tctaaatatg ataattcttt attaaatgaa ataaaagcta ttgaagatgt aacagatgtt
     4081 gaacccaata tttatttaaa aggatatcta agaaatgctg acttagaaga agattattta
     4141 gatgagctaa aaagaactga aataaataat aataatgagt ctacagtttt aattcgaggt
     4201 tacaataaag agctattaaa taatatagat aaatatatag ataaaggcga aaatgtttat
     4261 agttatacag acagggatta taaaaatgtt ttattggtaa ataattttta ttctagaatt
     4321 aaattgtcaa ataatactca gattataaaa tcacctaaaa taggagactt aatagatata
     4381 aaaattcctg tatataaaga tggagagtat aaatatataa atacaaaagt aagaatcgct
     4441 ggaataatga aaaatagcta tatatcagag caagatggag aatctcaatc aggtggaatt
     4501 caaattatat ttaatgaaaa ggatttaaaa gaattaacag ggataagtga ttataataaa
     4561 gtttttgtga agataaaaaa agaaacagat aaaaaagtaa taaaagaaat aaataatata
     4621 atagaaaaaa gtggattttc agatatagag ggaagatatg tacgtaatca ttttggagac
     4681 cattataata aatcctcata taaattagca atgatttgtg tatttggagt tttattaata
     4741 tcatctataa acattatttt tatagttaga tcaaatataa ttgtgaggtt gagtgagata
     4801 tgtacattta gagcaatagg gatgtccaaa aaaaatgtaa aaagaatgtt aataaaagaa
     4861 aatatgatat atggggtatt aagtatgatt gtagctggaa ttatatctag tttcaattat
     4921 tataaaatag tttctgaaac taacaaactt aatcaacagg tatatggtat aaataactct
     4981 attaaatttg aaattccaat atatgaaatt ctaatatttg gatctatatc tgtttttgtt
     5041 tgtgtcattg cagtttattt ttctaataaa atgataaata aacttagtat agtaagtggt
     5101 ataaaagaaa attaatgaaa tttctaattt aaatatatag gaaggaaata aaataaatga
     5161 atagctcaaa caaatatttt ttagattgta tatgtgaaaa aataataaat aataatcaag
     5221 ttattcttag taataaagta aatggaagat gggttaaaat tccaatagaa tgttatgaag
     5281 ttctaaagta ttcagtagat aatgcattac aacttggtaa tttgtatgat gtattccaag
     5341 aaaatgaaga taaaaaatat tatgaacgag ttatagataa gttagagcat ataggacttc
     5401 taagtgattc tattctaagt gaatttagac tagagagaat aaacaaaatt tcattttctc
     5461 caactaatag atgtaatcta agttgtgatt attgctgtgt agattctaaa atagataata
     5521 acgattattt agatacatct caagtaagaa aagtaataga taatatagtt aaattaaatc
     5581 caaggatatt aaccattaca ggtggagagc cattgatgag aaatgatttc ttagagctgt
     5641 tggattatat aaaagaaaaa tttaaaggta aaataattct gtctacaaat gcaactttaa
     5701 ttaaagaaaa acagattgat gatataatta atggtttata tgcaatagaa attagtttag
     5761 atggttatga tgaattaagt tgtagtgaag taagaggtaa aggagtattc tgtaaagtat
     5821 taaatgtgat tagacttata aaactaaaaa aattcgagaa cgtaggtttg tctatggtgg
     5881 taggaaagaa taatgagaaa gacatagaga aattcaataa attaaatgaa gatttaggta
     5941 caacgcctat aataagaaat tttatgaata ttggtagagg taatgagaac tatagcaaat
     6001 atcttaatga taaacttgat attgattaca tttgcaaaga tgattatgtg gatgaaagta
     6061 gtttatgttc aaatatgtgt aaagcaggtg ttaatcagat aagtatagat cataaaggag
     6121 atgtatatcc gtgtccaaac ttagagtata aggatttaaa gatattcaat atattagaat
     6181 ttaatgaaaa catattagag aggattctta atagagaaat ggatatattt aatatatttg
     6241 ataaattaaa accagtaaat attgagagtt gtaaagaatg taaagtaaat ttattttgta
     6301 caacttgtcc atcgaaaata tatactttaa aaaataacaa aaaaatgttt gatgcaaatt
     6361 gtaaaaaaat gaaaaacatc ttggaaccta tattatggta aggattagtt ttatattcaa
     6421 ggtaatttat tttagaggtg attattaatt gactaaagta agaatagcag tcttagacac
     6481 aggattagat gtaaatgatg atgatattaa tggaaattat gtttatgatt caaattttca
     6541 attgaaagat ttggggggga aggaaataaa tgacataaat ggacatggaa cttttgtatc
     6601 gaaaaccata ttaaatataa gtaaaaatac ccaaatttat cctattaata tatttaatga
     6661 ttctggaaaa acaagttctt taaatcttct tagtacactg agcaagttga ctatgtcgga
     6721 tatacagata ataaacattt cagctgcatc tattaatagt atgtatgaaa aagaattaga
     6781 aaaggtttgt aatattttaa atagtcaagg tagatttatt atttgttcaa aacataataa
     6841 atatgaagat aaagaaagta ttcctactat atttgaaagt gttattggtg tagtaggtaa
     6901 tgaaaatata tataaaaata atcaatatat atacgaacca gaaaataaga ttcaaatgta
     6961 tgcaaattca aaagataatt ttattaaatt taaagataaa gtaactcatt ttggtaaaaa
     7021 tagtaaggct tgtgcagtgg caactggcat tgttgcaaat atattaaaaa acaatccata
     7081 tattaagttt aatgaattgg aagaaatact tattcaaaaa agcaaaagta aagaagattt
     7141 aaaaatagaa aacttgaaca ctccaagtta taaatctaat ttgataagat tggatatagc
     7201 aaggaaaata ataaatgtga taaatagaaa cttttctaaa ataaaaatag actttgaatt
     7261 tgtaagtgaa tattctttat ttaacaattt tacatgtatt ggaaattata atgcatataa
     7321 ttttttaact attttaaata aagagtttaa tattagtatt gactacaaag aagtatactt
     7381 atatcaatta gagaatttag atatggcagt agatcttatt tacgaaaatt taatttaaaa
     7441 atatatgttt tttaaatggg aatggagata cgttatgaaa atacttaagg taaaagattt
     7501 aaaaaaaata tatggaaaat atgagaatga agttagagct cttgatggta ttgatttaga
     7561 tatagagcca cataaattta cagctattgt aggtgcaagt ggttctggta aaagtacact
     7621 acttcactgt gttgcaggct tagacaagcc aactttaggg aatgtgtact tagatgatgt
     7681 agatttatat acattaaatg atgataagct gtctgaaata agaagacagg aatttggctt
     7741 catatttcaa agttacaatt taataccagt tataaatgta tatgataata tagtacttcc
     7801 tgtgttgctt gatgggaaaa aagaagataa agaatatgtt atgagattaa ttaataagtt
     7861 ggggattgaa aaacaaataa agaaatatcc gaatgaacta tcaggaggtc aacaacaaag
     7921 agttgcaata gctagagctt tagccaatag accgtcagta atatttgcag atgaacctac
     7981 tggcaactta gatagtaaga ctacaaatga agttatgaat atgcttgaat ggtgtgttaa
     8041 agagtacaaa caaacactag ttatgataac tcataatgat aatattgcaa agacagctga
     8101 tagaattata actataaaag atggaaaaat agatgaaaaa aactattaat aataatttat
     8161 ttagaatact aaatataata gtatataaga ataagactaa gttgatagta tcatttataa
     8221 tggtttttat aattgctggc gtaaatattg taatacctca actaattaga tgtataatag
     8281 atgatggaat aggaaataaa aatatttttc tgcttataaa tttaatattg atatatattt
     8341 ttataaggat attatcagct acatttgatg ttatattatc atatttatat acttcaataa
     8401 aaaataaagt tactataaat ctaaaagtaa agttgcttaa ccatatatca aaactttctg
     8461 gtagatatta ttcaagtaag aaaacaggta atattttatc cattatggaa agtgatatat
     8521 ttatgataga aaactttgga gcagagatta tatttgatat tattgtaaat gtgtttacag
     8581 ctataatatc gttaattttc ttaattaatt tgcagtttga tttattttta gtagttttat
     8641 ttttacagtt gatattaaca ttttctcaaa ataaaatgac aaaacttata tctaagaaaa
     8701 tttctgaaat aagaagtgat tcaggcagtt tatcaaattt gattcaagag tacgtatcta
     8761 atattatgga tattgttata ttaaattcaa aaaagaattt ctttaataag tatttaaaga
     8821 gagagagaga tttgataaaa aaagatttga atttgaacat cattatgagt agtaatatag
     8881 caatatctca aatactaaca ggattgataa caatattaat atatggaatt gggggatata
     8941 aaataataaa taataagatg acgatggggg agttaatagc atttcaacaa tatacaggaa
     9001 tgttaattgg accatgtata gctatagtaa gggcgaatac tagaatagca caatcaaaag
     9061 tgtctatcaa tagagtattt tcagtaatag atgaaaagat agatattaaa gttgataata
     9121 atggatatag aatagataac agtgaaatta agaaaataga ttttaaaaat gtatctttta
     9181 gatatggtga ggatttaaac cttgttttaa atgatataaa tttacaattt gagaaagggg
     9241 aagtaacagg aattgttggt ggaagtggat gtggcaaatc aacaataaca aatctaatat
     9301 accgactttg ggatataaat gaaggtgata tattaataga tggtgttaat ataaaggata
     9361 ttaatttaaa atcactaaga aataatattg atatagtaac tcaagatcaa tttgtatttg
     9421 atgacacaat aaaaaataat atagtattaa ataataaaat aagtgataaa gaattagatg
     9481 agatattaga agttacttgt ttagatgatt ttataaaaaa tctagataag ggattggacg
     9541 aagtagtagg agaaaaaggt gtcaaaatat caggaggtca aaaacaacgt atatcaatag
     9601 ctagagcttt agtaagtaat aaaaaggtac ttattctgga cgaagcaact tcagctctag
     9661 ataatatttc acaaaaagag atattgaaca acttgaaaga gtacatacaa gataagatag
     9721 ttattataat agctcataga ctttcaacaa ttaagagtgc tgataatata tatgtattag
     9781 ataaaggtag agtaatagaa tctggaaatg atgctgaact tctacataaa gatggtttat
     9841 ataataagtt agttgaaact gcagattttg cataagcatg actttgtatg tacatatatg
     9901 attattaggg tatttaatgg aatctataag ttatataact aatttagtta tataaaagtt
     9961 tgcaaatcaa tctcagataa tgttaaacaa atgattagta tatccagtag aaaaattata
    10021 atagtagtag aatatattac aaataaatca aaacttcaca taattttcat attaattatc
    10081 aattaaattc acacacaaga gttattatat aaa
//
LOCUS       DAYAKB010000111         9806 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.112, whole genome shotgun sequence.
ACCESSION   DAYAKB010000111 DAYAKB010000000
VERSION     DAYAKB010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9806
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.112"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(229..1515)
                     /locus_tag="ACGI3L_003379"
     CDS             complement(229..1515)
                     /locus_tag="ACGI3L_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFG9199073.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(1530..2795)
                     /locus_tag="ACGI3L_003380"
     CDS             complement(1530..2795)
                     /locus_tag="ACGI3L_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFG9199074.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            3111..4208
                     /gene="ychF"
                     /locus_tag="ACGI3L_003381"
     CDS             3111..4208
                     /gene="ychF"
                     /locus_tag="ACGI3L_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFG9199075.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(4687..6966)
                     /locus_tag="ACGI3L_003382"
     CDS             complement(4687..6966)
                     /locus_tag="ACGI3L_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9199076.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(7237..8691)
                     /locus_tag="ACGI3L_003383"
     CDS             complement(7237..8691)
                     /locus_tag="ACGI3L_003383"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HFG9199077.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            8855..9724
                     /locus_tag="ACGI3L_003384"
     CDS             8855..9724
                     /locus_tag="ACGI3L_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9199078.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
BASE COUNT         3386 a         1522 c         1050 g         3848 t
ORIGIN      
        1 aaatttttta aactaaatct ctcatgacta aagttacaag tgtacataga tattttttaa
       61 tcaaaaagat tgatgcatat atacatcaac ctcttctaat tcttatctat agctcttaaa
      121 tttttacctc aatttatata aatatatttt ataaatttgt tttaccaaaa taaacattta
      181 aaaacataaa ctaatactta attagttatt cttattatga ttaagtttct atttaggctc
      241 tacaatagaa ataacacaat actcttcttt aaaatgctct tttaatcttt cttcaacttc
      301 ctcaaaagta atatctttaa taatatctaa ataatccaat agatttatat ccttaaaaac
      361 ataagatata aaactattac ctataaagtt tatagaatca aagcacttaa taaatgaccc
      421 tatttttttc tttttagttc tctcaaactc ttcttttgat aatccttctt tttttgattt
      481 ttctatataa tcaagaatta tttcttttac ttttttaggc tctttagaat ctccagctat
      541 tatgctaaaa gcataatcca cttgagacga aaatccagct ccaaaatttt catttattaa
      601 accttgcata tacaaatctt cataaagctt acttcctttt ttaaataaca tccctacaag
      661 tatatcagtt acaatctctt tacgtaaaag ttctttccct tttaaaccaa cattgctatc
      721 tttaaaacct atgttgaaca taggcataga tatagggaat ttttctataa cctctttttc
      781 ttttacactt tctggttctt ctggataaaa tctttctata ctcttagaga gtctgtctac
      841 tttgtaattg tttgactttt tagttacatc tataactttt tctacatcta agtcaccaac
      901 aacaaataaa gccatatttc ctggattata gaaagtatta taacatttat atagctcttc
      961 cttagttatc ttatatatac tatcaacagt acctgctata tcaattctag caggataatt
     1021 tacatacatt gccttcaagc aattaaagta tacattccaa tcagggtcat cattgtacat
     1081 ttttatctct tgtgctatta tacctttttc cttttcaaca ttttcatctg taaaataagg
     1141 tgtttgaaca tagtcaatta gatgttctaa actctcataa aaattttcag tagcagaaaa
     1201 taagtaggct gtcattgtaa aattagtaaa tgcatttgca tttactccta attttgaaaa
     1261 tttatcaaat gcatctcctc catcaggttg ctcaaacatc ttatgctcta gaaaatgtgc
     1321 aataccttca ttcactctaa ttttcttatc ttctccaatt ggtacaaatt ctaagtcatt
     1381 tgaaccataa ttagtagcca aaatagcata ctttttcata aaaccccttt taggcataaa
     1441 atatacatct aatccatttt gcaatttctc ataataaact tcttctttca atatatcatt
     1501 aactattttt tccatagaca tctcctccat taatttctca agaagtatac agtatcaagc
     1561 tctatatttt ttatagcttc aactatatct ttttttgtaa ccttttctat actagatatt
     1621 atgtcttgta cttcagaatt tgtctttgcc atagactgag agaaaacaaa atcagacata
     1681 ccacctatat tatcagttat agatttcata gaattaacta aagcaagttt actgttttct
     1741 aattcttcat cagatatatc acctgctttt acactttcta cttgtttttt tatcaattct
     1801 acagctttat cataatcttt agtttctata ccagatgata taaacatgat acttttatac
     1861 ttctctattg aagagaatat atagtaacat aaactttctt tttctcttac attaacaaat
     1921 aatttagagt gtggaccacc acctaagaca ttgctcccaa ctactaaagc ataatattta
     1981 tctatgtctg cataatccac atttgctcta taacccataa ctaacttacc ttgagttatt
     2041 tccatttgtt catctataac ttttacctca tccacatttt ttataaaatc tgctcttggt
     2101 atatttataa tttcttctct ttcaaatttt agatttttac ttattatatc tacaacttta
     2161 tcttcatcaa aattaccttc tacaactata tctataggtg atgttttaag tatgttttta
     2221 taatgttcat ataactctct tgaagttata ctatctattt catcttcata accaaattca
     2281 cttacactat atctctctcc tttacacata gcctcaatac atttatcttg cgcatattcc
     2341 tttttatcat ttattattga ttgtatcttt tctcttaaat tctctttttc aatatttaaa
     2401 tattcttctt taaacccacc atctacaaca agcgtattat ttattacttc attaaaaaat
     2461 tctactactt cttcaaatat actctcatct aaatactttt cacttatgtt aattacttta
     2521 aaactcaata cttgacgttc tccacgtttt acagcatcag ctcccataga tgaaccatat
     2581 aaatcatcta atttattgga tattgctcta gcactaggat atttagcgct tccacttgct
     2641 attattgatg gtattagagc attttttgta gtttcttttt catccaatag tctctgaaca
     2701 tataaactta taagattcga tttaaacttt tctgttttta tcaaagtaag attaatatta
     2761 ttacctaaat ttattatttt tttagtatta accatatgta cctcctattt ttatttaaac
     2821 atcaatttta aaattgaaat ttatttattt tttaattaca tatactcaca tataaaaacc
     2881 ttctatttaa ttatatcctt tttattattt tctaaaagca atatttttat ttaaattaaa
     2941 tacaaatatt atttaaatca atatgcttta aagtctagtt tacaagcttg atatatatga
     3001 tgtataatca atatgtatgt ctataattaa aacaattttg caatcctata gattgattgt
     3061 ttaaagttat ataaagaata taaaaaagaa taagagagag gacgattaat atgaaattag
     3121 gtatagttgg tttaccaaat gtaggtaaaa gcacactatt taacgcaata actcaagcag
     3181 gtgcagaatc tgcaaattac cctttttgta caatagaccc aaatgtggga gttgtatctg
     3241 ttccagatga aagattaaac aaactacaag aattatataa ttctgaaaaa atagttccta
     3301 ctgctataga attttgtgat atagcaggtt tagttagagg agcttctaaa ggagaaggtt
     3361 taggaaataa attcttatca catataagag aagttgatgc aatagttcat gttgttagat
     3421 gttttgagga tgaaaatgtt gtacatgtag atggttctgt agacccactt cgtgatatag
     3481 aaactataaa cttagaatta attttctcag atatagagat tcttgaaaga agaattaata
     3541 aaactcaaaa agctgctaag gctgataaaa ctttaggttc tgaacttgat ttattaaaat
     3601 caataatgtc tactttagaa gaaagtaaat gtgtaagaac tatggaattt acagaagatg
     3661 aacaaacatt cgtaaattca ttggatttac ttacatctaa gcctgtaata tatgcttcaa
     3721 atgtatcaga agatgattta gctgataatg gagaaaataa taaatatgtt caacaagtta
     3781 aagcatttgc agaaacagaa gatgccgaag ttgttgtagt atgtgcacaa atagaagcag
     3841 aaatttctga acttgattct gctgaagaaa agaaagagtt tttagaaaca ttaggtcttg
     3901 aacaatcagg gcttgataag cttataaaat cttcttatgc tttacttggt ttaatttcat
     3961 tcttaactgc tggtccaaaa gaagttagag catggactat aaaagttgga agtaaagctc
     4021 ctcaggcagg aggaaaaata cattctgata tagaaagagg atttatcaga gcagaaacaa
     4081 tagcctttaa tgatttggtt gagcatggta ctatggctgc tgctaaagaa aaagggttgg
     4141 ttaaattaga aggtaaagaa tacatagtta aagatggaga tgtaatatta tttagattta
     4201 atgtttaaaa tgattaatcg tatacacttt gactattata tataataact aaaaaactaa
     4261 gattataata atacaatatt atcttataat aattatatag aatttaaaaa taaaagaaga
     4321 gtatttcaaa tgatttgtat aaattattat gaaaaactct ttttttgata taataaaatt
     4381 acttacatat ataatattta aatttataaa ttatattttt attttttaaa atatgtataa
     4441 cacacctata gaaattacta ttattactat ctaaagtatt ttgctataat cccatatact
     4501 cttacctcaa aaacattcaa atgtaaaaaa tactacatat taataaactt tgcccaataa
     4561 ttcctaaaat aatatcctaa caatgattta tgtttttata atagtatatt tttacataaa
     4621 aaagtgaaca ttgattaaca aagttcactt ttttataaat ttttatgtta taattcacaa
     4681 ttttatttaa tttgtttctt ttctatttaa actatatcta tctaatatta atttttcata
     4741 ttcttctatt ggcattggtc tagcaaataa aaatccttgg gccatatcac aacctataaa
     4801 ccttaaaaac tctgcttgct ctacagtttc aacaccttct gaaacaactt ttatatcaag
     4861 ttgctttgcc atttgaacaa tacttgaaac tacaatttga ctcttttttg catttcccac
     4921 tgttataaag aattgcctat ctaatttcaa tacatcaatt ggcatatctt taagcatatt
     4981 taaagaagaa taaccagaac caaaatcatc catagaaatt ttaaatccaa cagatttcaa
     5041 agtttgcatt attttaaata atatttttgt attgtcaaat attgcacttt ctgtcaattc
     5101 aatctcaatt aaatttggtt caatttcata ttcttttgtt attctttcaa gctcagaaat
     5161 aaagcctgga ttctcaagat gtactcttga taagtttatt gatataggaa atgtggggaa
     5221 attttcattt tcccaacgtt taaaattttt acaaacttgg gtaaatacaa acatatccaa
     5281 ttctgttata aaaccatttt tctcaaaaat aggaataaat acacctggac ttattagacc
     5341 ttttttggga tgttgccaac gtacaagtgc ttcagcacct acaattttag tagttgataa
     5401 atcaacctta ggctgtaaat aaactttaaa ttgttcattt tttaaagcat catgcatttc
     5461 ttgttcaata tcacgttctt ctatgagagt ttcttttaaa ttttcagcat aaatctcata
     5521 aacttttaaa tattttcttt ttactgtagt ttttgcaatc atagctttgt caagacaggt
     5581 agaaatattt gtttctccct cttcaacaaa atatacacct atggatggaa ttaaattgag
     5641 ttctactccc aaacttgttt ttatcattga caatttttta cgtataagtt cacatatttc
     5701 tataattgac tctctattat ttttcttttc aaatattata gcaaaattgt catttgaaat
     5761 tcttgaaaat acagattgct ctttaaatat attcttaatt atctctgcta tttcctttaa
     5821 tactctatct ccttcttcat acccaaacct atcatttact agcttaaact tatctatatc
     5881 aaaataaatt aaaactagat tctttttctc atgagaggat aaaaattttc ccccttcaag
     5941 attaaattta tttgaattgc caatacctgt aacgttatct ttaaaagcaa attcttccaa
     6001 tttttcctta ctctttttat gtataaatag tatataaatt gttaatgccg taaagattat
     6061 aatcaagact acacatgctg ataatgtaag ttttataata gcatatgatt tctcagatat
     6121 agcagtttta ggaacttcag aaaaaagata ccaatcattg attcctattg gggcataact
     6181 taaataatat ccttttccaa acatactata acttaatgaa cctgatttaa agttttttat
     6241 atttgacttc atattgttga tactagattt tgatattgaa tcacttctgc caatgtaaga
     6301 aaataaattt tctttagtag agttggcgtt tttactgctt ggatttaaaa caatatcacc
     6361 attacttcta gttatataag aatatccttt tccattaaat gtaggtacag aaagtatttt
     6421 ttcatacaac ttcgtactat gtgtggcaaa tataactcct ttaacctcat tatctttata
     6481 aattggtaca gaatatacat taatattact attggtattt ttatcatctt ctattacatc
     6541 ttttaatttt cctgttataa ccacttctcc ttgcattgat tttaagaaat aatctctttt
     6601 agagaagtct tctatataac catctgtagt gtatgctgta ccatttggta aaataactcc
     6661 cattctttta aatgaactat taatagcttg tctttttagt atagaaagga tattatctac
     6721 ttcaaaagac tcttctcctt caataaatat tgaaattgac tctagtaact ttatatctcc
     6781 attaatttgt ttttttaaca cattgacgct ttgatttgct atttctgaaa gatattgatt
     6841 cgtttcttca cctaatgtct tattcaacct tgaaccataa atcaaacagg aaattgtaat
     6901 tactaagata cttatgacag caattatgga caaaccatac ctattatttt ttgcatcact
     6961 taacattatg cttcctgcct ttctcgaatc tatgtatgta taatcattat cttatgacaa
     7021 ttattgtaaa cattttataa taatacttat ttttccatat ttactgtaat tatacaaaat
     7081 tataaacttt attacaacaa taaattaatt aatatagata ttagtgttta cattattgca
     7141 ttatctattt tacaattatt tacatataaa aaaatgtaat atcaaagtga agcttgatat
     7201 tacatttttg ttcttgtatt ttgtttaatt tttatgctac atcttactta aacactcatt
     7261 tgcaacttct ttatcatcaa aatgatgctt aactttacct ataatttgat aagtttcatg
     7321 tcccttacct gttataatta caacatcatc cttttttgcc atacttatag cttctgctat
     7381 agcttgttct ctatcaacaa caacatggta attttctttt ttcttgtcaa ttccttcaag
     7441 tatatctttt attattgcct ctggttcttc agttcttgga ttatcagaag ttataataca
     7501 taaatcagaa tatttttgtc caattgctcc catcaaaggt ctcttttcag tatctctatc
     7561 tccaccacac ccaaacacag aaattatttt tccttctgca aattgttgag ttgtctttag
     7621 tacattttca agtgcgtcag gagtatgagc atagtctaca attacgctta tacctttatc
     7681 atttggaact gtttcaaacc ttcctgatac tccattagaa agtctaaggc cttctttata
     7741 tattggttta ggtatgccaa gtacatagca agcagctata actgctaaag tattatatac
     7801 tgtaaacatc cctggaactg gtataaatat tacttcttca tatgaaggtg ttattaatct
     7861 ataagatact ccatccgaat ctgattttat atctctagcc ataaaatcag ccttagtatc
     7921 aacaccataa gtgtaacaag gtacatttat accttttata ttttcatata tcttttttcc
     7981 accttcatca tctatgttta ttatatttgc catagtagtc ttaaaaaata atttttcttt
     8041 tgcttttcta taatcctcta aatctttatg aaaatctaaa tggtctggtg ttaaatttgt
     8101 aaatatgcct agtttaaagt ctgtttcatc aactctattt aatgccaatg aatgtgatga
     8161 aacttccatt gcacagtagt cacatccatt atccaacata ttattaaaat gatattgtaa
     8221 atctatactt tctggagttg ttgaattgga aacaatgtct ttttctccat caaaaatttt
     8281 tatagttcct ataagtccaa ctttattctt atttaaagtt aatatctcat ttagtatagt
     8341 agttatacta gtttttccat tagtacctgt aactcctata acgttaaatt tttgagatgg
     8401 atgattgtaa aaattatcag ctacttttgc catatctttt cttgtatctt ttacctttat
     8461 aaatgtacat ccttttattg ctacatcttc ttcaacaaga aatgcacttg ctcccttttc
     8521 tatggcatct tttatatact tatgaccatc tgacacaaat ccttttatac atataaataa
     8581 tgtacctttt gtaacctttc ttgaatcata ttgtacatta ttaatatcta tatttaattc
     8641 acccttgaca ttgattatat ccaacccctg tataatatca tttaatttca taaatgcttt
     8701 cctcccttta aactctttct gctaaaatta cactacatat aatattatat taagaatttt
     8761 ttactatgtg aatggttaaa aatgcttgaa acattgcaaa aaatgctcta taattttcta
     8821 taatataact gaggaaaggt cttctataaa aactatggat aataaaatcg ggtacttaaa
     8881 cgataacttt aaaatattta atattagaga taaaaaagat atacaatttg aataccataa
     8941 tcatgatttt aataagataa ttatatttat aaatggaaat gtaacttatt ttgttgatgg
     9001 tattccctat aaactaaagc cttgggatat actctttatc agcaataatg aaatccataa
     9061 accagttata gattcaaatg tcttttatga gagaattgca atatggatta gcccagaatt
     9121 tatgaaaaaa aatagtgatg ctagtagtga cttagaaaaa tgttttaaaa tagctacaga
     9181 gaataaatgc aatagattgc gtttaaatat gcatgatatt gaatctatta agagttttat
     9241 tgagcaaata aatatttccg aatccaatac tgaatttgga aatgaaatat tgagaaatac
     9301 attatttata caacttatga tattcttaaa cagaattttc ctaaaaaatg aaaatatgga
     9361 atcaacagaa gatgtttttt atgatgaaac tattaagaaa gtattaaact atataaattc
     9421 aaatatagat gataagcttt caatagatag catatcgtct gaatttttta taagtaagta
     9481 ttatcttatg agaaaattta aatctcatac tggaacgtct atacacaatt atatagttca
     9541 aaaaagatta attttggcaa agtcactaat aaccaatggt caccttatga gtgaagtttg
     9601 taataaatgt ggattcaacg attattctag ttttgtaagg gcatttaaaa aaaactacgg
     9661 tgtatctcct aaaaattata taaacaataa aaatccttta gatattactc ttttagatga
     9721 atagataatt tatgtaaatt ttattttaat aaaacttgaa gtattagtgt atttatctta
     9781 ctaatacctc aagtttttta atgttt
//
LOCUS       DAYAKB010000112         9271 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.113, whole genome shotgun sequence.
ACCESSION   DAYAKB010000112 DAYAKB010000000
VERSION     DAYAKB010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.113"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(12..1829)
                     /gene="ftsH"
                     /locus_tag="ACGI3L_003385"
     CDS             complement(12..1829)
                     /gene="ftsH"
                     /locus_tag="ACGI3L_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFG9199079.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            complement(1860..2303)
                     /locus_tag="ACGI3L_003386"
     CDS             complement(1860..2303)
                     /locus_tag="ACGI3L_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9199080.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            complement(2794..3684)
                     /locus_tag="ACGI3L_003387"
     CDS             complement(2794..3684)
                     /locus_tag="ACGI3L_003387"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HFG9199081.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            complement(3714..4979)
                     /locus_tag="ACGI3L_003388"
     CDS             complement(3714..4979)
                     /locus_tag="ACGI3L_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HFG9199082.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     regulatory      complement(5089..5191)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(5245..7932)
                     /locus_tag="ACGI3L_003389"
     CDS             complement(5245..7932)
                     /locus_tag="ACGI3L_003389"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HFG9199083.1"
                     /translation="MKKRKEWSSKMENHKQMPWHSRATHEILESLDSSEEGLTDTEAE
                     KRLKENGLNELRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIV
                     TVNAVIGIVQEKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAM
                     VPADLRLIETSSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGR
                     GVGVVVATGMDTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGA
                     FYQRPLLPMFMIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGG
                     ATVICCDKTGTLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCN
                     DACINPDKTDEILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVH
                     NIDEKIIAYTKGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGF
                     AKREISSIPKEDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHK
                     VTATTIAHELGIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSL
                     KRIGEVPAMTGDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIK
                     EGRRVYRNIQKVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALA
                     LGVDPPSRNIMKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQ
                     TMAFCVLAFSQMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRN
                     AFNLTVLNNLEWLVTIVLAIMSVIQVEVGKIIKRKKLKK"
     gene            complement(8030..8773)
                     /gene="yaaA"
                     /locus_tag="ACGI3L_003390"
     CDS             complement(8030..8773)
                     /gene="yaaA"
                     /locus_tag="ACGI3L_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFG9199084.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            complement(8783..9247)
                     /gene="bcp"
                     /locus_tag="ACGI3L_003391"
     CDS             complement(8783..9247)
                     /gene="bcp"
                     /locus_tag="ACGI3L_003391"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HFG9199085.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
BASE COUNT         2844 a         1728 c         1102 g         3597 t
ORIGIN      
        1 gtataatcat tttagtttaa gttaagtatt tccataaact catcacctgt aatagtttct
       61 ttttctaata aataattagc aagttcatgc aatttatcaa tattattttc taagatttca
      121 attgcatttt tgtgacaagc ctttactatt ttaaatacct cttcatctat tttagcagca
      181 gtgtcggaag aacaagcaag agaagtatct cctcctaaat attgattgct tacagtttca
      241 agagcgacca tatcaaactc ttcactcata ccaaggcgag taaccatagc tcttgcaatt
      301 ttagtagctt gttctatatc atttgatgct cctgatgtac aagtgttaaa gataacctct
      361 tcagcagcac gaccacctgt aaaagtagtt attttatcaa ttgcttcttc tttagacata
      421 agtacactct catcttcagc aacttgcata gtatatccca atgctcctga agttctaggt
      481 attatagtaa tcttatggac aggtgcagaa tgtttttgca tagcagcaac aagtgcatga
      541 cctatttcat gatatgctat aattttcttt tccttatctg aaattacagc tcctttacgt
      601 tgatacccag caattacagt ttcaacagat tcatcaaaat cctgttgttc tactatatct
      661 ctgccagact taactgctaa aagtgctgct tcgtttacaa tatttgcaag ttctgcacct
      721 gatgctcctg atgtagacct tgcaattgca ttataatcta tatctgagct tacatttaca
      781 ttttgagcat gtacctttaa tatagcttca cgtcctccaa ggtctggaag ttcaactggt
      841 atacgtctat caaatcttcc tggacgaagt aatgctttgt caagactgtc aggtctattt
      901 gtagcagcaa gtattactac tccaattcca ccatcaaaac catccatctc acttaacaac
      961 tgatttaaag tttgttcacg ttcatcattt ccacctaatc cacttccatt atcacgcttt
     1021 ttaccaatag tatcaatctc atctataaac actatacatg gagctttttc ttttgcttgt
     1081 ttaaataaat cacgaatcct agaagctccc attcctacaa acatctcaac aaactcagaa
     1141 ccagatattg agaaaaatgg tacatttgct tcacctgcta cagcttttgc aaggagtgtt
     1201 tttcctgtac ctggaggtcc tactaaaagt gctcctttag gcatttgtgc tcctatcttt
     1261 ttatactttt ctggattgtg taagaaatct actatttcag ttaaagcttc ttttgcctca
     1321 tcttgaccag ctacatcatt aaatcttttt ccactttgag cagatacata cattttggcg
     1381 ttgctttttc caaattgcat agcattacca cccattcgct tttgcataga cttcatcatt
     1441 aagttaccaa atagcataag aatacctata ggtattatcc atgtaagtaa aatacttaaa
     1501 agaggtgaat tttccttagg aataacctta gtaaattcta cttttgcatt ttttagtcta
     1561 tctaccaatt ctgggtcatc cattctacca gttatgtata tattcttatc cttgctacta
     1621 gatggattta ttgctattct attattttct atctcaacag atttaacctt tcctgtatcc
     1681 aacattgtga gaaactttcc atagtcaatc tcaaccattt ttttatccat taaacttgga
     1741 aatattaaag catttaaaaa cattactact attattataa ctgtataata atagagtgct
     1801 gacctttttt ggggtttatg ttcatccata attttattct cctttaaatt atttttatgt
     1861 tatttgcaat caatgtaagt taaaagttta tttaatttct ctaaaccttc tattatatct
     1921 tccatatctt gcaatttttc actggtcata ttttcaaaat aactatcaaa aatactactt
     1981 gaaatatgtt cttgtatatc caatgattta tttgtaactt ttacttttac aattcgttgg
     2041 tcttctatat ctcttatgcg atttaaaaag ccattttttt caagcctttg acagattact
     2101 gatacattac tatttgtcat gtttaagttc ttccctaaat cgcttatttt tttctctcca
     2161 tgttcacata actcagataa aatcaaagct tgcactgctg taataccaag tggctgataa
     2221 aaatcactta ataaagttgt aaatttcata tttatatctc tagtcaactc tagtagctct
     2281 ttcttaaaac tcatctcatc catacaaacg ctccctacga aaatacttta tttcaaattt
     2341 aggctgaagt gcatactgta aataaatact taacactata atgtttaatg tattaaatat
     2401 tatagtatta agtatttatt gtcaattaca atattgtaac ttcaattgaa attttgttat
     2461 cttattgata tttaatttta tacaggatat ttttaataaa atttaataaa aaatctatat
     2521 atatatttta cactgatttc tcccttttta atctctttta aaagttaaaa tacaaattta
     2581 ttgatactat aaaggtttag tctcccatta tcgcaccata tataaaatta aagccacctc
     2641 tatctacata cacctaaagt gattttctta aaatataaaa ctactattat aaggtcaaat
     2701 tttaaaaaaa taaggtataa agtatcatta agattaactt tatacctata aatttctata
     2761 tttttttagt taacatttat atactcttaa aatttattgt atcaaatagt tttttatcca
     2821 atttctaaac aacaattctg aatgtttttt ccattttaca gttggctctt ctgaagggtc
     2881 atcattaata tagtaatttt gaggtataga tattttatct cctttattta tatccctctt
     2941 atattcttta tcaagagtgt atttgtcata ctcgctatga cccattacga acacatctct
     3001 tgaatttgta attatatagg gaccagcttc tttagaatga ctcacaatgc tcaactcttt
     3061 attctctttc aaagcttcaa tatttacagt agtatgtctt gaatgtggag caaaaaattc
     3121 attttcaaat ccatctacta ttttactatc tttatctacc ttatgcttaa atactccaaa
     3181 acatttttga cttagtggaa gtttttttac attgtagtat ttgtaaagac ttgcttgagc
     3241 tgcccaacat atatataatg tagatttagt ttttctctta gaataatcca taatttcttc
     3301 tagttcattc caataatcaa cttcttcaaa ctccatttgt tcaactggag ctcctgttat
     3361 tataaagcca tcaaaatact ctcctttggc ttcatcaaat gttttataaa attctttaac
     3421 atattcatta caacttcttt tactttctct tgttgaaatt ttaataaatt ccacagacac
     3481 gttgaatcct gttttatcta tccttcttag taaatctaat tctgtatcta tctttatagg
     3541 cattagattt agtatagcta tcttagtgtc tatgttttct tcatacttta attccttttt
     3601 aaaatcttct ttataaatta catctattcc ttcatctaat aatttattaa taacaggtaa
     3661 tccctttggt agtattaaag ccatatcttt tcacttctct ttctcttaga atattagaaa
     3721 tttaaagctt gatttaaatc agctattaaa tcctctacat tttctattcc aacagataat
     3781 cttattagtg aaggcaatac tccagatgca attaattgtt cttctgttaa ttgtctatga
     3841 gtagttgaag ctggatgtat aacacaagtt cttacatctg aaacatgtgt aaccaaagat
     3901 gctatctgta atttttccac aaattttttg gcattttcta acccacctct tactccaaat
     3961 gataaaacac cactacatcc tcttgataaa tactttttgg cattctcata atacttgtta
     4021 tcttcaagtc ctgggtaatt aatccaatct acattttcat gtttttctaa aaatctagct
     4081 attttaagtg cattttcact atgtctctcc attctaagat gtagtgtttc aacatttaaa
     4141 ttagtaagat acgcattgaa tgggcttaaa caatttccat agtctctaag caactgaact
     4201 cttgctttag ttgcatatgc ggcatttcca aatttttgag tatagcttat accatgatat
     4261 gttgggtctg gctcaactaa ttctggaaat tttccattat cccagttaaa gtttccacca
     4321 tccactataa ttcctccaac acttgaagca tgcccatcta aatattttgt ggtagaatga
     4381 gtaactatat ttgctccata ctttaaaggg ttacaaagca ctggagatgc taatgaatta
     4441 tcaacaataa atggaacatt aattctctta gctacatttg ctattttttc aaaatctatg
     4501 acttcaagag ttggatttgc aagtgtttct gcaaacacaa ccttagtatt ttcctttgca
     4561 agttctacta tctcatcttc acttgaatct aagtcaaacg atattaaatc tataccaaat
     4621 tttttaagac taggtcctag taaattgaat gttcctccat atacttttga agaacaaagt
     4681 atactatctc ctgatttaca tatatttaaa actgccaaca tatttgcaga ttgccctgat
     4741 gatacagcta cagaagatac tccaccctct agtaaactta ttttttcttc aaaagcttga
     4801 atagtaggat tgcttattct tgaatatata tgtccatcaa cttttaaatc aaataattca
     4861 gcaagttggt ctatactgct atatttaaaa gttgtacttt gatataaagg tagtactctt
     4921 ggttctccat tacctggttt ataatttcct tgcacacata ttgtttcttt attatacatt
     4981 cttgtatccc ccttagattt tagtaaaaaa aattaaacta tttaccagat gagagttaaa
     5041 ataaataaag cctgagtata taactcaggc tctgtataag cttaattata ctcatctctc
     5101 agctttcgcc gcaggattta gcaccaatgt atataaatat actggttgcc gggtttcata
     5161 gggccagtcc ctccacctct ctggataaga tttatttaat ttttctatgt tttatatctt
     5221 atatattttt cctaattttg tcaactattt ttttaatttt tttcttttaa taattttccc
     5281 aacctctact tgaattacag acattatggc taaaacaatc gttacaagcc actctaagtt
     5341 atttaaaact gttaagttaa aagcatttct aaaaacaggt acaaatagta ttactgctat
     5401 taaaaatgca gaagttaaaa atgagattaa aagaaatgga tttttaccat tatttctatt
     5461 aaacattgaa tctgtatttg aacgctgact aaatgctcgt aacatctgtg aaaatgctaa
     5521 tacacaaaat gccattgttt gacctacaga atgattttct atattaagac caattttata
     5581 tgctaaaata gtcattattg ccacaaatat accttgggta acaactcttt gtataagatt
     5641 tttttcaaac aaagtggttg atttcactgg ctggtgcttc attatatttc tgcttggtgg
     5701 gtcaactcca agagcaaggg ctggaagcgt agcagttgca aggtttaccc atagaatatg
     5761 aacagcaaga agcggagtat cccaatttaa taatattgct acaaacaacg taagtatctc
     5821 tgctatatta ccaacaagca aaaattgtat aactttttgt atgtttctat atacacgtct
     5881 accttctttt attgcataag caattgttgt aaaactatcg tccattaaaa tcatgtcaga
     5941 agaatctttt gcaacatctg taccacttat acccatggct ataccaatat cagcagactt
     6001 taaggcagga gagtcattta caccatcccc agtcattgct ggtacttctc caattctttt
     6061 tagagattgt ataattctaa gtttatcaaa tggggataca cgagcaaata ctgtagtatt
     6121 tttaacagct tcatctagtt catcatcact caaattatca agttcatcac cagatatcac
     6181 agtattttct tcactccata ttcctaactc atgagcgatt gttgtggcag taactttatg
     6241 gtcacctgtt atcattatgg ttcttatacc tgcttcttta caagtactta ctgcatcaat
     6301 tacctcagtt cttggtgggt caatcatacc aaccatacct ataaatgtta aatcatattc
     6361 tatattttca ctatcttctt ttggtataga tgaaatctca cgcttagcaa aaccaagtac
     6421 acgcaatgca tctttagaca tgttaagaca taattcgtgt atattctttt tatccacttc
     6481 agtaatgttt ctttcacctt ttgaagttaa tattttagta cataggtcaa gaatttcgtc
     6541 tactgctcct ttagtataag caataatctt ttcatctata ttatgaacag ttgtcataca
     6601 ttttctatct gaatcaaaag gctgttcaaa tacacgtgga tattcttctt caagagcttc
     6661 ttgatctatt ccaaattttt tggccataaa aattaatgcg ccctctgttg ggtcacctaa
     6721 tatttcatct gttttatctg gattaataca tgcatcatta caaagtgcac cagcataaac
     6781 aatctcttta tacactaatg gatgtttttc agatgcagta tctattgatg tcacttttcc
     6841 agattcaaaa tctccattga cagcaatatg tgtaacagtc attttattta aggttaatgt
     6901 accagtttta tcacaacata ttactgtagc tcctcctaat gtttcaacag caggtaattt
     6961 tctaattaaa gcatttcttt tagccatacg ctgtacgcct aaagccatta caatagtagc
     7021 tgttgcaggt aatccctctg gaataattga tatggcaagg gaaattgcaa tcataaacat
     7081 tggcaagaga ggtctctgat aaaatgcacc tattgcaaat ataacaacgc atacaataat
     7141 acctatgaca cttaatgtct ttccaacagt attaagttta cgttttatag gagtatcaaa
     7201 atcatcttgt gaatctaaaa gatgtgctat gttacccact tctgtatcca taccagttgc
     7261 tactacaaca cctacacctc taccatatgt gactattgaa gatgtatacg ccatattgct
     7321 acggtctcct aatacacatt ctttaggtaa gattgtatct gcatcttttt ctgatggaac
     7381 agattctcct gttaaagaag cctcttgaat ttttaaactt gatgtttcta ttaaacgaag
     7441 gtctgctgga accatagctc catcttctaa aaaaacaata tctcctacta caagattact
     7501 tgctggaata acattttctt caccatcacg cataacacga gctgtaggtg aattcatatt
     7561 ttttaatgct tctaatgatg attctgcttt tttctcttga acaattccaa taactgcatt
     7621 tactgttaca attattagta ttacaaaagc ttctgtaaat tcgccaaata tcaaagataa
     7681 tattgctgct cctattagta tcataaccat agcatctgta atttgactcc aaagcatttg
     7741 taaagttgtt ctaggtggtt tttttctaag ttcatttaag ccattctctt taagccgttt
     7801 ttccgcctcg gtatcggtga gcccctcctc tgatgaatct agactttcta aaatttcatg
     7861 cgttgctctt gaatgccaag gcatctgttt gtgattttcc attttggaag accactcctt
     7921 tcttttttta atttaagaat aattatattt taaaatcaag ttcaattcaa tacacactaa
     7981 gtatatttta cctaaattta acaatgccat ttaatattta acaaaacttc tactctttta
     8041 caaatatgta ttcactattg ttagataagt tttctttata cttataacct tctaaatcaa
     8101 actttttcag ttcttcaata tctcttatcc tattttttac aatgtatttt gtcatcatac
     8161 ctctagcttt ctttgcttgt gtagattcca ctttcaatat gccattttta tttactttaa
     8221 aagtacatgt aatatatgta tcactatctt taataaattt ttctatggat ttgctgtatt
     8281 catttgatga aagattaacg atagctgttt tttctttgat tagttcttta tatatacgat
     8341 ttccccaata ttcgtataaa ttcttaaact cacctacttg taattttgtc tgcatttcta
     8401 atctatattc atatatacta tcatatggtt ttacaacacc atacaatcca cttatgattc
     8461 gaatacagct atttgcaaac tcttcatctt tccttgtaaa attttctgct tctatatttt
     8521 tatattgtat tccatcataa gttaagattg cagggtttcc taatctatca aatttaatgc
     8581 tttcaaatct atttttattt aatacagcta atttttcatt aattttcatt ttatttttaa
     8641 aatcttctat accaaatgtc tttatatttt ccactatttc ttttgtgtta tctataaagc
     8701 aaggcaaact caaatctcta tcaaatactt ctatattctt catattttta gctggtgata
     8761 acattataat cataaattct tattactcct gtttttccaa atattcaaga atctcttgtg
     8821 catttgtgtc tggttttgct ttttcaaaga ctttttcaat aattccattt tcatctataa
     8881 tatatgtcgc acgtacaact cccaatgcag tttttccata catttttttc tctttccata
     8941 catcaaaagc ttttatagca actaagtcag ggtcagaaag taaaataaaa ggaagttcat
     9001 gcttttctgc aaatttttga tgtgatttta tactatcttt acttatccca ataacttgta
     9061 tatcttcctt tttaaatcca tcatatgcat ttctaaaagc acaagcttga cgtgtacatc
     9121 ctggtgtatt atctttagga taaaaatata ctactacttt tttgccttta aaatctgaca
     9181 tacttacctt atttccatct ttatcttcta gtgtaaattc tggtgctttt gttcctatac
     9241 tcaacataaa tatctctcct tttgttttta t
//
LOCUS       DAYAKB010000113         9250 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.114, whole genome shotgun sequence.
ACCESSION   DAYAKB010000113 DAYAKB010000000
VERSION     DAYAKB010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9250
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.114"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            239..2596
                     /locus_tag="ACGI3L_003392"
     CDS             239..2596
                     /locus_tag="ACGI3L_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFG9199086.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2682..2999)
                     /locus_tag="ACGI3L_003393"
     CDS             complement(2682..2999)
                     /locus_tag="ACGI3L_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HFG9199087.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
     gene            complement(3583..4854)
                     /locus_tag="ACGI3L_003394"
     CDS             complement(3583..4854)
                     /locus_tag="ACGI3L_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9199088.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            complement(7096..7647)
                     /locus_tag="ACGI3L_003395"
     CDS             complement(7096..7647)
                     /locus_tag="ACGI3L_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9199089.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            7838..8800
                     /locus_tag="ACGI3L_003396"
     CDS             7838..8800
                     /locus_tag="ACGI3L_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFG9199090.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
BASE COUNT         3537 a         1012 c         1343 g         3358 t
ORIGIN      
        1 aagaattgtt gaatttatct tgccttaact ttatttactc ttttatatta agaaaaactt
       61 aactaaaata tagcgaaatt cataaaaatt taggaaatct taagaattat aatatttaaa
      121 tctttagatt tatattttat tatataaact atagaataat aaaataaaaa aattgagaat
      181 tttataatat atttgtagat ttgagtataa aaaagtgcta agttgaaagg agtaaaatat
      241 ggataaggtt aatttagaaa ggtatagttg tgatataaat gttggtttaa ataaaaatca
      301 acttcaaagt agaatagatg ataatttaat taatgcattt gataatggaa aaaccaaaac
      361 atataaacaa atttttaaag acaatatatt tacacttttt aatctcataa atattgtttt
      421 agtctgttta ttagtttcag ttggttcttt taaaaatacc ttatttatat ttattgctgt
      481 aattaatact attataggag taatacaaga gataagagct aaaagattat tggacaatct
      541 atctgttata gtttcaaata aggtatctgt cataagagaa aaagagaaaa aagagattga
      601 tgtacaagaa ttagtattag atgatattat gattttaaaa acaggtaatc aaatttgtgc
      661 agattcaaaa gttttaaatg gaaaattaga ggtaaatgag tctttggtta caggtgaatc
      721 tgatattatt ataaaaaata aaggcgattt tttatattct ggaagttttg tagtttctgg
      781 agaagctttt gtaagagttg aaaatatagg aaaagataac tatgcaaata agatagctaa
      841 tgatgcaaag atttctaaaa aacataattc tcaacttaga aattcattaa atgcaatatt
      901 aaaaattgta ggtataataa taattccttt aggaattata ttgtttgcaa aacaacattt
      961 tggaaatgga gattctatag ctacatctgt agtaggtaca gtggcagctg taaatggtat
     1021 gataccagag ggattaacat tacttacgag cattgctcta gctgtaggaa ctataaaact
     1081 tgctagtcat aaaactttag tgcaagaact gtactgtgta gagactcttg ctagagttga
     1141 tacactatgt cttgataaga caggtacaat tacagaaggt aaaatgcaag ttgatgatat
     1201 agtaatgttg gaagaagtgg atattaatga aataatgggg aatatatgta attctctcaa
     1261 agatgataat gcaacactaa atgcaataag agataagtat aatgttttag atacgtataa
     1321 agctaagaat ttaataccat tttcttcaga aagaaaatac agtggggtta cctttgaaaa
     1381 taaaggtaca tatttattag gtgcatttga atttatattt aaggaaaaaa ataaaaaact
     1441 taggatagaa gttgaaagat attctaaaaa aggaaacaga gtaatagttt tagctcatag
     1501 tgattcttat atggaagata ataatattcc tgaagatata aagccactag cttttatatt
     1561 gatattggat aaaattagag atgaagctaa ggaaacttta gaattttttt acaatgaagg
     1621 tgtagatata aaaattatat ctggtgacaa tcctataaca gtaagtgagg tagctagaaa
     1681 agcaggtctt aaaacagcta gtaattttat tgatgcaaca acacttaaaa atgatagtga
     1741 tatatacaaa gcagttgata aatacagtgt ttttggaagg gtaagcccac aacagaaaaa
     1801 acaaatgatt ttagcattaa aaaaacaaaa tcatacagta gctatgactg gagatggtgt
     1861 aaatgatgtg ctagcactta aagaagcgga ttgtagcatt gccatggcat ctggaagtga
     1921 tgttactaag aatgtgtcta atttagtctt attagattca aactttgcat caatgccaaa
     1981 ggttgttatg gagggaagaa aagtaattaa taacattcaa agagcatctt ctttgttttt
     2041 agtaaagaca attttttcat tcttcttgtc gttattaaca ttattcttct tcagtagaca
     2101 gtatccattt gttcctatac aattatcact cattggggct gtaacagtgg gtataccatc
     2161 attcttctta gctcttgaag caaacaaaag tagaatttca ggaaattttt tactcaatat
     2221 attaaaaaat gctttaccag gagcactatg tgtgacagta aatgtaatta ttgtttacaa
     2281 tatagttgaa tatttaggtt atagttcaag tgtattttcc acaatgtgtg ctatattaac
     2341 tggtgtatgt ggtcttttaa tattaagaca acaatgtttg ccatttaata aagaaagatt
     2401 atttttaata gtaagtatga ctattgcatt tgttattggg attctatttt taggtggatt
     2461 attctcattt gtagcattga gtagagaatt aattctcata actatggcat tagcaatatt
     2521 aatgccaatt atgataaaag ttatgttatt tgtcttagat gagatattag agacaattgt
     2581 tccagattta aattaatttt aaaatgatat aaataagagc agttttagtt gaactgctct
     2641 ttttagatgt gtttaatttt atgtaagaat atgtattttt attaatcagc tatatatgag
     2701 caacagtagt caacaacttc attaaccttt aagtcaaaac ttgaatcact aggaacatta
     2761 aatttttgcc cttctttata agttacaaac tcattgcttc caggcagttt tacatccata
     2821 cttccagcaa gcatctccat tatttcttct tctctagtag aaaaagtgta ttctcctggc
     2881 aacattaatc ctaaagtttt tctttctcca ttaggcagta ttattactct gctacttacc
     2941 ttaccatcaa aataaacgtt tgccttcttt actgcagtaa cattcttaaa ttcactcatt
     3001 agataaaacc tccaaaatta tttgtacata tatattatat aaaaataatg taaaaaatgc
     3061 tatatattta caaaaaaatt tagtatttat taaaaaaatt aataagaata aaaaagagat
     3121 gaaattgctt aaattgataa aaaatataaa ataaattgca aagtaagcaa gaaaagaata
     3181 agttgaagag ttatatatta taaatattaa aaattttagt attaataaaa aagatattac
     3241 attaatatga aaatatagga gattagaagt gtttgataat tacagtacat gttagatata
     3301 tcattgtaaa ttaacatagc tttgaatata ataatgttca gaaggcaata tttttgaggt
     3361 ctgaatccaa taataatata gtcttatgat tgtagatatc aaaaaatgta agttactagg
     3421 aatacgtttt gtagatttat atatgattaa taactaaagc tataaataaa caaaataaaa
     3481 agagtatgtt tcaacctata gcttttagat ttaaaatata ctcttttatt aattatagtt
     3541 gtataaatta accataatat ataattaaaa tttttattat aattatatat taggttcttc
     3601 aattagtttt ccacatacat atctatgaat gatatttcta tcatcaccaa catatataaa
     3661 tctttcaagt ctttcaagta tagaataatt gtcatgattt aaatttgaat catcaataat
     3721 caatgcatca aaatcataac cttcttcaaa gctaccaact tttccaaaga aacttccacc
     3781 acttttggtt gcaatataaa aagcctcaga taaagataag aaattatact tcttaccaga
     3841 gttaacccaa tataatttag ataattgtat tgcagatacc attgctttaa atattgacaa
     3901 tgtatgtcca ccacttatat ctgatccaag tgctaatcta atattattat cgattaattt
     3961 tctgataggc atagcaccac taccaacatt aaagttagaa gctggacagt gaactgccat
     4021 aacattattt tctctcatta aatctatttc atcctgagaa caatgaacac aatgagccat
     4081 taaagtagga gtttgaccaa ataaattata tctattatat gcatctccat agaatttaga
     4141 ttcaggttct agacttctaa cccattcaat ctcatcataa ttttcagata agtgtgattg
     4201 aataggaata ttatatttta aacataaatc tcctaaacct tttaaaagtt cacttgtaca
     4261 gcttggtata aatctaggtg ttattattgg ttttacaata gaatctgtat cactatactt
     4321 atttataatt tcttctgtat cagtaataga atcctgagtg ttttctaata aagtatcagg
     4381 gcaattcata ttcatattta ctttaccaac gtatgctcca agaccaactt ctttgaatat
     4441 atccataagt ttcatagagg cttctttatg tactgttgca aacactgcta ttcttgtagt
     4501 tccagatttc caaagttctt ttacaaattt tttatacatt tttgttgcat attctatatc
     4561 tttataattt gattcttctg gaaatgtata agtttcaagc catggcaaaa gctctttatc
     4621 catagccatt ccaagatttt taaattgaga ggcatgggca tggaggtcat tcataccagg
     4681 tattataagc ttatcagtgt aatctactac ttttaggttt ttgtattcct taggtatctc
     4741 tttaaatatt ccctttactt tacctttttc cagcataata taactatttt caaatactgt
     4801 gaaagtttct gaagtttttg taaaaattat atttcctttt agtactttta acatataggt
     4861 ctccttagtt ttaaatttgt tttaatatat gtaggtaaaa ttttgtttta caaatcaaaa
     4921 ttttaccaca tgtattatat caaatctaaa ctataaatac tattagataa tagcaaatat
     4981 tagtgaaata cagttgttta ctattattat atataactga catttaagtg acatttaaga
     5041 aaaatataat gcctacttac ataaaatgga atgttattta aagagaactt tgattatatt
     5101 ttcagaagtt tttttatcca tatcgtttaa aacaagaaaa tatctattca tagttatttt
     5161 tatattagta tgtcctaatc tttcagagat gatttttata ttagttctag ctagaagaag
     5221 aactattaga atagataata tagtaagtat ttacaaatat gtaggtgttc ttaaattgat
     5281 aaattattcc attttaattt tatagtttga attttatgat ataataaaaa tatataaatt
     5341 ttgcagtgag cgatattttt gataaagtag ggtttaacag ttgcaatgta agggattgag
     5401 ggtgtatgat aaatgttatc aattgcacta ctcatggttc actgcaaatt tgagagagtt
     5461 gtatgtgtgt aagtactgaa aatacttagt ttattttggg gttttatatt aactaagtgg
     5521 tatgtaaata aataatgtgt tttatcatca taactcctgc taaacatgtt ttatattaac
     5581 tatgtggtat gtaaatcttg ttaatgcaaa taaacaacat agcactatta atagttttat
     5641 attaactatg cggtatgtaa atagggtttc tgataaaatc ttcaaacatg taaaatatgt
     5701 gttttatatt aactatgagg tatgtaaatc ttatacttag ttagaactat atatcgacac
     5761 aaatatgctt tatattaact atatggtata taaattgcaa tttttattcg ttgtccaatc
     5821 tctttgaaat ttgttttata ttaactaagt ggtatgtaaa tttgtaacaa gtataggtaa
     5881 aataccccaa taatttatac agcattttat cctttaaaat ataattattt tttatcattt
     5941 gtagtaaata attaccagat aacattgact ttagttttaa tgattaaaat ataaaagtag
     6001 aataattata aaaagtattg aaaaatttat aaatatatat aataaaactt aatgacaaga
     6061 tattagatat aaaaaataat taccttataa atagattgaa atttatgaat attcatacta
     6121 taatttaaat ataaggagat gccctttgaa aataaaaatt aaaaaatatt taatgctact
     6181 acaataggaa ctagaactac acttaataaa tatacagaaa ttagatttgg ctcaatataa
     6241 aatacaaata tagaatttag gtgtttttta tgaaaaaatt tttatatgct ttatatagtt
     6301 tcattgttat tatagctaat tttagattaa aagaaaaaaa ttataacttt attttattag
     6361 caatcttttt tatattgctg ttaattcaaa atggagtttt aaaaacaggt tatcaaaata
     6421 gagctacatt ttatcaagat aattatttta atagagagga taaaaatgat aagataaaat
     6481 ttatgactat aaagattttt atatttttgt cattaccatt atgttttaat atactattca
     6541 attatttaac ctcttaaatt atatttagat ataggagtct tatgataaaa gtaagcttat
     6601 gtgttatttg tagtaaatat aaagtgcata tagtgataaa acaaaagttt catataaatg
     6661 aagaaaaaaa tataaaataa tttatttaac tacttaaaaa taaactaaaa gggataataa
     6721 aatagctttt aggttatggt aataaaggta tttaaaaaga gtgcataagc actccaattg
     6781 tgagaaatac atacacaaat cattattaca acaatgaaaa atgtacatat aagagacgtt
     6841 ttgtatttgt tttaagtgat aatattttaa tactaactaa ataattatca caatagtaaa
     6901 aaagaaaaag gagtattttg tactccattt gtcaaaaata taaaactttt atataagctt
     6961 attataacat aattgataaa agtgtaaaga tatataatga atttataaag aaaaataaaa
     7021 taaaaaagat aaatcctaat caaaggattt atctttttgt atagaaaata attattctat
     7081 tattaaatgg catggctaaa ctggataata atttattatt actgctttca atgttttttc
     7141 tccttgatta tggtatgtat gaattgattc agctgaaaaa caaatagagt cattttctct
     7201 aagttgataa atagagtcat ttacttctaa ttttaattga ccttctataa tcataatata
     7261 ttcctgtgat ttttcagaat gaccaacaga tgtataacta tgaccttctt ctaattccat
     7321 ttgaaataat tcgaagtttc tagttggtgt attgggataa taacaataaa gacgataatc
     7381 tttattttct gaaacttgta catctatatc agtttttgat acaataaaag tttcattttg
     7441 aggttgttcc agtattgcag tatatggaac atttagtcca cttgcaattt tccaaattgt
     7501 gtttactgtt gggtttgagt ctcccttttc aatttgcgaa agcattactt tacttacgcc
     7561 agataattca gcaagttgac ctagacttaa gttacgttca ttacgtaatc tatttaaatt
     7621 tttagcaata acagtattaa tactcatagt agctccttaa aatgtaaatt attgacaaat
     7681 ataatttacg aatgtataat ttatttaaca ttatttataa tttacaaatg tataatataa
     7741 tgaacgttaa atacactgta catccgtaat ataaattata ctgcataaag agttgttttt
     7801 caacggatga tagttgagag attaaggggg aattgtaatg cgtgtactta ataatgttac
     7861 agaggctata ggcaatactc atatgttaca tttatccaaa atagcagatg aatttggagt
     7921 tcaaggtaat atttatgcaa agatggaata cttaaatccg ggatttagta aaaaggaccg
     7981 tgtagcatta caaatgatta ccgaagcaga aaatgcaggt ttattagttc caggtcaagc
     8041 agttgtggaa ttaacaagtg gtaatactgg aacaggacta gcaatagctt gtgcatgtaa
     8101 aggatataaa tttatagcgt gtatgtcaaa aggaaattct atggaaagag caagaatgat
     8161 gaaagcttta ggtgctgaag tagttcttgt agaccaaatg cctaattcag ttcatggaca
     8221 ggtatctggt gaagatttgg cacttgtaga aattgaggct caaaaaatag caaaagaaag
     8281 aaatgcattt agagcagacc aatttaattt agaagcttgt aatcatgcac atgaaaagta
     8341 tacagcagaa gaaatgtggg aacaattgga tggaaatatt gatgtatttg tagattttct
     8401 tggaagtggt agtacttttg caggatgttc aaaaacactt aaaaaacata attcttctat
     8461 caaatgttat gttgttgaac ctgaaacagc agcaatttat tcaggtaaag aaataactga
     8521 ccaagggcat aaaatacaag gtggaggata ttctatggat ttgccattag tagacaagaa
     8581 acttattgat ggttatattc aagttacaga cgaggaggca actgatgtag caagaaaatt
     8641 agctaaatta gaaggtgtat ttgcaggatt ttcttcaggg gcaaatgtat gtgcagcaat
     8701 taagttgtta aagagcagtg aaaaaggaaa aaatatagtt ttaactctta atgatagtgg
     8761 tttaaaatat ttaagtactg atttatatga agaattgtaa taatagcaca atagttatgc
     8821 aatgtttttt aaattaagta tatagattta aattataaaa agtatctcaa tgtaattttt
     8881 gaaagttata aaggagatac ttttttattt tgtaaatatg gagtatccta cttataagta
     8941 ttaagctata tagatattga tgattagcta tgcaataaaa aagagtatgt gtttttgcat
     9001 ttatacatca taacttggaa taatacatat taatgttcta aatgtattta aaacatatga
     9061 taaaattaga acaaatagat acaaggagat aaaaatgcaa aagagaattt taagaaattt
     9121 tatatttacg ggtaaaaata ttttaagtaa acttgttttt ataataaaat ataattttag
     9181 tacattaatt ttatttgaat tatttcataa aggattagcc ttatttttta tatggccatc
     9241 tattagatat
//
LOCUS       DAYAKB010000114         9191 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.115, whole genome shotgun sequence.
ACCESSION   DAYAKB010000114 DAYAKB010000000
VERSION     DAYAKB010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.115"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            393..1598
                     /locus_tag="ACGI3L_003397"
     CDS             393..1598
                     /locus_tag="ACGI3L_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9199091.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKG
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="ACGI3L_003398"
     CDS             complement(1669..1890)
                     /locus_tag="ACGI3L_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199092.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="ACGI3L_003399"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="ACGI3L_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFG9199093.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="ACGI3L_003400"
     CDS             complement(2643..2993)
                     /locus_tag="ACGI3L_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFG9199094.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="ACGI3L_003401"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="ACGI3L_003401"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFG9199095.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="ACGI3L_003402"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACGI3L_003402"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="ACGI3L_003403"
     tRNA            complement(5068..5159)
                     /locus_tag="ACGI3L_003403"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="ACGI3L_003404"
     CDS             complement(5160..5615)
                     /locus_tag="ACGI3L_003404"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HFG9199096.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="ACGI3L_003405"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="ACGI3L_003405"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFG9199097.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="ACGI3L_003406"
     CDS             complement(7666..8547)
                     /locus_tag="ACGI3L_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFG9199098.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="ACGI3L_003407"
     CDS             complement(8559..9068)
                     /locus_tag="ACGI3L_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFG9199099.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2943 a         1598 c          973 g         3677 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttatttttt ttatttatca tgtattcttt atatttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt atcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa acttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaaggtattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ttacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatggtact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataacg tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctactataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt ttttaaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctatatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tattgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatctct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtaac
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta aaaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaaatata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggcgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta cgatgacatc ttttataata ccacctaaat ccacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag a
//
LOCUS       DAYAKB010000115         9159 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.116, whole genome shotgun sequence.
ACCESSION   DAYAKB010000115 DAYAKB010000000
VERSION     DAYAKB010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9159
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.116"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            156..647
                     /locus_tag="ACGI3L_003408"
     CDS             156..647
                     /locus_tag="ACGI3L_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199100.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            675..1622
                     /locus_tag="ACGI3L_003409"
     CDS             675..1622
                     /locus_tag="ACGI3L_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199101.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGYIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            1912..2454
                     /locus_tag="ACGI3L_003410"
     CDS             1912..2454
                     /locus_tag="ACGI3L_003410"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9199102.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            2782..4275
                     /locus_tag="ACGI3L_003411"
     CDS             2782..4275
                     /locus_tag="ACGI3L_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9199103.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            4349..4582
                     /locus_tag="ACGI3L_003412"
     CDS             4349..4582
                     /locus_tag="ACGI3L_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199104.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            4738..5502
                     /locus_tag="ACGI3L_003413"
     CDS             4738..5502
                     /locus_tag="ACGI3L_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9199105.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(5787..8966)
                     /locus_tag="ACGI3L_003414"
     CDS             complement(5787..8966)
                     /locus_tag="ACGI3L_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFG9199106.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGINKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
BASE COUNT         3594 a          959 c         1306 g         3300 t
ORIGIN      
        1 gaaagacttt tacttgtaaa ttgaaatcaa tgaagtaaaa aaggattctt tcttaaaagt
       61 aaataacaac tagatagtga ataataaaaa atggtaattt gaaataattt ttatgaatag
      121 tattaatata tagatacagg gagattgatg cgattatgta tgaaaataat aaggtaatat
      181 acaaccttga aagatgtgaa aaactagaaa agactcttta tttatctcaa tttaatacat
      241 ataaaaattt taaattagct tctaaaaaaa ctgtaataaa ttcattagag acatatgttt
      301 acaatatgaa tattaacaat ataagtcttg ttgatactat agaatgtata tcattagaag
      361 atgaacaact tacaggaaag aagttgattt tagttggtga tatagatatt gatgcaatat
      421 tagattatgc aggcaataaa agaaatagaa attctagtaa aaaaaataca tttaaattaa
      481 aaataccctt tagtacattt atacaaatgc ctagaaagat agaaaataaa gataaaatta
      541 atttaaagta tcttatacaa gatattactt catctatttt agatgataat ttatttatta
      601 gtgttactgc aattataagt tatgaaaata gttccaagat agagtaatct ttaaattata
      661 gaaaggtgga tgcaatgaga ataacgaaaa ctacttttaa tgatgtattt tcaaatgatg
      721 caaatggaag tattataaaa gtagaaaaat atgttgataa aaaatgtgca tctgtatttg
      781 agattttgac ctacactatt attgttacaa atacaagtag gtacaaaact ggaaatatat
      841 ttttcaaaga ttatatttct aaatatatag agtttataaa taatacggta aaagttaatg
      901 gcattataaa acgtggatta gacccacagc aaggttttta catagggaga atagatgcaa
      961 gttgtaaaaa aataatatct tttaagagtg tagttttacc aaattctgca cataggatta
     1021 taaagaatag tgctaatata tactattatt ataagtgtaa tctagataaa ttcccaacaa
     1081 gaatatcaat agaaagtaat agagtttata ctaatgtaaa taaaattgta ttcaaacaat
     1141 tgaatataag taatacttta aaagctccta aaaatctaag agatatatta aaagtaaatg
     1201 taaatagtaa aatatttgat gttaaaccta tgaaaaatct tataaacaaa ggtagtaatt
     1261 tgaaattatg taacttgata gtttttgggt atatagaagt tgaaatagac tatagttgta
     1321 aaaataggag taattttaaa acagtaaata agtctaatga cattaaaaaa gataagtatt
     1381 ataaaaatga tatacaaaat aacaatgaaa atataaacga ttgtaaaaag caaataagtt
     1441 ttggtgataa taaggtaaaa aaaataacaa aaacttttgg attttcttgt ttcatttgtt
     1501 ctccagttgg aattatttat gaagatatga aaaatataaa tataaaaatt gaacatacat
     1561 caataaatga attaaatcca gaagaattat ttgtaaatac atcactttta ttgtattatt
     1621 aagtatttta aagctaaaac ttaaacttat taaaatagca tttggttaaa ggaaaataga
     1681 tattgatata tttatcatat atataaatga ttaattaaac aattataaat aataagtata
     1741 gtataatatt taaaaaatat agatttatga taaaataaga caaatatgtt aaaaaaatga
     1801 taatcacgga gaacttttac cttcttcaat taatatatta ttattagtaa taactttaaa
     1861 attatattac tattatataa aaattggctt aaaagaaggt gaaaaaagta aatgaaaata
     1921 tgcataacag taggtcatag tatactaaaa ggtggtaaaa gtacaggtgt aaatggtata
     1981 gttgatgaat acaattataa taaaaaatta gctcctatgt tagctgagat gcttataagt
     2041 caaggtaata cagtagatgt aataatttgt ccagaaaggc actttatgtc agaaagagaa
     2101 gaatttttct atagagttcc aaaagtaaac agtggtaaat acgatttatt agtagagcta
     2161 catttaaata aagctgatgg aacacaatgt ggtacagaag tgctttacta tggcactgaa
     2221 ggattagaat atgctaaaag agtatctaat agacttggag aattatttga aaatagagga
     2281 gctaaaaaaa gagaaaattt atatatattg agaaatacaa atccagttgc aatacagatt
     2341 gaaagttttt tctgtgataa tgtgaatgat tgtaacaaag caaatgaatc aggttatgat
     2401 tatatagcac gattgattac agaaggtata ttgaataaag atataaatat gtgagattat
     2461 ggtgatttag gtattgatta atacctttta atattagata taaataaaaa tacaatgtat
     2521 tagtataatt taaactttca aaagatagat tagtttgatt attgacaaga gatacctcct
     2581 tgaaaatatt gatttatcag tatatttaag gaggtattta aatataaaaa tttaattaat
     2641 ttgctactaa actataggtt tatagagtat atacttttat cttcagtcta ataaataata
     2701 taaaaatagt agaaccttgt attataataa tataatgtag aaaaatatat agataagata
     2761 aatataataa ggtggtaata tatgaaatat acatttgaaa aatttaagtt aaatgaaaag
     2821 atacttaagt cattgaagag tttaggatat aatatacctt ctagagtaca aagagaagtt
     2881 attccaaaat tattaaaagg tcaaaactta gtagttaggt caaaaacagg aagtggaaag
     2941 acagcaagtt ttgcaatacc tttatgcgag aatataaatg tagattacaa taatattcaa
     3001 gctcttatag tggttccaac aagagaatta gccttgcaag taaaagatga gatatcagat
     3061 atagggagac taaagaaggt gagatgtagt gctatatttg gcaaacaatc tataaaagac
     3121 caaatagctg aattgaaaca aagggttcat attgttgtag ctactccagg cagaatactt
     3181 gaccatataa atagaggttc tattaagttg gaaaatgtaa agtatttagt aatagatgag
     3241 gcagataaaa tgtttaataa aggttttgtt gaacaaatgg aaaaaatatt attaaattta
     3301 cctaaggaga aaatagtaag tcttttttca gctacaatag atgaagagat aaaatatata
     3361 tgtgaaaaat atatgctaga ttacagtgtt ataaatatag aagaaaatga gagcgatact
     3421 aatcaaaaaa caagacaaat agatgacaaa ataatcaagg caaatggaag agagaagtac
     3481 atccttttaa aagaattaat atacagcgaa aatccaaaga gtgtgataat attttgtaat
     3541 accaaagaga aagtatctaa attatataac aagatgagta aagagggttt tttaataaga
     3601 gagttacatg cagatttatc acaagaaaga agaatttttg taattaagga ttttaaaaac
     3661 caaaaattta atatattagt tagtagtgat gtagcgtcca gaggaataca tattgatgat
     3721 atttctttag taataaatta tgatgtgcca caagataaag aaaactatat acatagaata
     3781 ggtagaactg ggagaaaagg aaatagtgga aaggcaatta ctatagtaac tgaaaaggat
     3841 gaaaaatata tagagaatat agaaacgtat ataggatata aaataaatga attaaaagat
     3901 atagaaaaaa gtagaattac acatggcaaa gttttgtttg aagaatattc aaaaggaatc
     3961 ctaaaaaaag tatcaaagag aaaaaaagtt gataaaaatt cttacaaaag taaagatata
     4021 aaactaaata tagaaagtga agttgttaaa ttatatttaa atgctggtaa gaagaagaaa
     4081 ataagagttt tagatatagt tggtgcattt agtaatataa aaggtataac taatgatgat
     4141 ataggtgtaa ttgaagttca agatttatgt tcatatgtag atatattaaa ttataaggga
     4201 gatttgatat taaaaaaata taaggagata cctataaaga aaaaaatggt taaagtgaaa
     4261 agagatatac gataatttag tcaatattga tgaattgctt tgttatcgaa atgaagttgc
     4321 aaaaaacaca atagaagttg ttaaggattt gaaagctgaa gatatgaaac gaaaggtctc
     4381 tccaattgac ttagaaagga ttttggtgac tggaggagta ataaagcatg aagattctat
     4441 ttggttgttg gacttttggg ggaataaaga tattgctgga attttgctta tgcctcctac
     4501 tcgtcatgtt atacttcatt tgaatgattg ttgtaaatgg aaggaatatt ttcgtacaaa
     4561 aaagaaattt tacagaagtt aaattataat aaattagaca aacaatagat aaattagcaa
     4621 ggaatgttga ttttatctac attctaagtt atactatttt taagtggcta agggaatagt
     4681 cattttaaat ataagtaata aatatatacc tatagggata ttaaaggggg gaaatatatg
     4741 gcatatttta actataacga caaacagtgc tactataatg aaattgggga tggtacacca
     4801 ttactttttt tacatggaaa tacagcctct tccaagatgt ttaatgatat aatcaatttt
     4861 tataaagatg aatataaagt aatattaatt gattttgtag gtcatggaaa atctcaaatg
     4921 gtcgataaat tttctgctga cttatggttt gatgaggcta tgcaagtgat atgtttttta
     4981 gaagcaatga actataaaaa agtaaacata attggtagta gtggaggagc tcttgttgca
     5041 ttaaatgttg cacttgagag acctgattta gtgaataagg taattgcaga tagttttgaa
     5101 ggagaagttc ctctagagtc atttgtacaa aatgtgaaaa tagagcgtga agcatctaag
     5161 caagatgatg gtgcaaaagc tttttatatt tataatcaag gagaaaactg ggaaaaagtt
     5221 gtagataatg atacagaagc tatttttgaa cattataaaa ctataggaaa gttttttcat
     5281 aagcctctag aaactatgca accagaggtg cttttaacag gaagtagaga agatgagttt
     5341 gtatctctaa tatctagtga tttttttgaa aatacttttt cattacttct tgaaaagatt
     5401 aaaaatggta aaatgtattt gtttgataaa ggtggtcatc ctgcaatttt atcgaatgga
     5461 ttagattttt caaatgtagc aaagaaattt ttagaggaat aatttaacca aaatttacaa
     5521 taatgaaaac tgtaaaatgg attgcaaaac ttacaaaagt gagtgtacat atacttcatt
     5581 attatgatga aataggattg ttaaaacaaa atattctaat agtcaagtta ttacatttgt
     5641 atatgcaata tgtatagaaa gagatatcat tagattgtaa agttgggatt aaataacaat
     5701 attaaatttt atttattcag atattttagc ttaactatat aaatgttaga acaaattcat
     5761 atagttaagc tgtaggatta aataatttag ttaaataagt ttattatctc ctcatcagat
     5821 agacttttta atacaccttc attagaaagt tctccattta taaattgatt tataagctct
     5881 tttttacttt cttgtaattt tattattttt tcttctatag tccctttagc aatcaatttt
     5941 ataacttgta ctgaattttt ttgaccaaat ctatgagctc tatcactagc ttgattttct
     6001 actgatggat tccaccatgg gtcaaagtga attaccatgt cagcagatgt aagatttaaa
     6061 ccagttccgc ctgcttttaa agatattaaa aaaacttttt tatccatact attattgaac
     6121 tcatctacaa gttcaagtct ttctttggca ttagttttac catctatata atggtattta
     6181 attttatact tatcaagttc cttacttatg ttcttaagca cagaagtaaa ttgtgaaaac
     6241 aataatattt tgtggttttc gtttatacta tccctaagta tttctaaaca tgtttcaatt
     6301 tttgaacttt ttttattgta atcttttact actatacttg ggtctaaaca aagttgtctt
     6361 agtttagtta aataagagaa tataactatt ttatctttct ttagattttt atctttcatt
     6421 ttatcttgta tatcttttga atatacacta tatatctttt tctgctcttt attcaattca
     6481 acaaaaaagt ttttttcaat cttatctgga agttctttca taacttgttt tttacttctt
     6541 ctaagaataa aaggttttat caattttttc aggtttttaa cattatcttc tttatttata
     6601 aacaattcct gaaactttgc tttactatat agatagccag gcattataaa atcaaatata
     6661 gaccataatt ctagtagatt attttccata ggtgtaccag tgagtgcaaa tttattttct
     6721 gcatttatac tttttacaga ctcagttact aaagccactg gattttttat attttgagct
     6781 tcgtctaata tacaataatc aaactttatt tcactatatt tgtctaaatc atttctaaga
     6841 gtaccatatg ttgtaagtat tacatcaaaa ttttctaatt ccataaaaca tttttctcta
     6901 tctcttttat ttccatgtat caataaaact tttatatctg gagcaaactt ttcaaattca
     6961 tttttccaat tataaatgag tgatgtcggt gtaacaataa gacttttttt attagataat
     7021 gataataaaa atgcaatagt ctgtattgtt ttaccaagac ccatttcatc agctaatata
     7081 ccaccaaatt tataataatc taaaacttta aaccaattga ggccatttat ttgatagtca
     7141 cgaaggtttg catttaaatt tgcgggaatt tctaaattta tgctatcaaa atttctaaat
     7201 ttttcacata tactgtctag ttctttttta ccatctataa actttaaatt tttactacgt
     7261 attacatcat ttatatatag agctttattt ttatgaattt tattattttt tgatttatcc
     7321 attatatcta gattttcaac taattcaaaa aaatcttttg tttctctttc tgataaatct
     7381 ataaagtttc catctttaag tttataaaaa gtacgttttt cttgaaaagc tttcaaaata
     7441 tccttgtact cttttggatt tatatcagat atattaaaat taaattctag gtaattctgg
     7501 ttagtctgat tgattgaagc ttgaattgat gaagcgttat atattttttt caatttaaac
     7561 ttctcagaat aatatatatc tccaaattcc tttagagatt ctaattgtaa atctaaaaat
     7621 gtaaataggt catggtcagt tcctttaaac acataatgat tattttcctt tgtaaattgt
     7681 gaagaagtaa gtttattttc aatagtagct tccttttgta tgttggggag cacaaatttt
     7741 ttatcttcat catcatatat atactttaca tcacaacata tgttgccatc aatcatatca
     7801 aagtagaact cagatttaaa atcttttgtt atattatttt ttatgttatc atctaaatga
     7861 acttcttgag atatagattt taatctagga actagcaatc ctaaaacatc cttagaatcc
     7921 tctttatcaa attttaactc tttagtcttt gataatattt gatatatttt tgaataatca
     7981 tgagcttttt tatgtgataa taaatagata ttgccatcat ataaaagtac atcatttttt
     8041 ttagtaagtg gaacaggtag tgaatcttta gaatataaga ctattttatc ttctatattt
     8101 ttaaaatcaa accttacagg tagagtatca tttaatatct ttggatgata ttcctcttta
     8161 gaaaaaataa gggtaaaatc cttgtactta atagcattta aaaattgttt taaagagctt
     8221 gcatttatct ccataaattt ttttgaatgt gatgaagaaa agttgtatga aagatttgtc
     8281 ccatattctt ctataatatc tactaacttc tcatcttcat cagcaaaata atgagtgttg
     8341 gggttgtaag taaatttctt cccaaaatct aattcatatc cattaagttt tgaatatgca
     8401 aattcagtaa tgttttttaa aatgtacatt ttattaattc ctattttaaa ttcagcaatt
     8461 gctttatttg aatccacatt tatcaataca tctaaattaa ccctttctct tttagtattg
     8521 tctaacaaag aaagtaattg cttgcttaaa tctaagctgg ttttagaatt tgtattagaa
     8581 agcttatcct tatctgcacc taatatatct attagaatag gaggaacatc ttttttattt
     8641 tttatttgtt ttaagctttt tatcacaata gcaactatat gcttacatat aaaaatactt
     8701 ttgccctttg attgacagtc agcgcaacta caatcatttt caattatctt aaagtgcttt
     8761 atatctatag ttattgaatt aaaataaaag ctataattat cttcagaatt gactccacca
     8821 cgaaatgtca acagattatt ttgtaggtca tcaatatcta tgtctatata atcaactaat
     8881 tgattagtat aatattttac acctcttgac catcttgatg gttctgtatt tcttcttatt
     8941 agtttatata tcatatctat tttcatatta ttcaccttac ctcactgtat atattataat
     9001 ctaaatgcat tcaatttaca ctctaaattt aagactaaaa ttaaggcaga tatgaatagc
     9061 ttttatctat cacgatatat gtgtaaataa caatttacta ttagattttt attgaattat
     9121 cttataaact atgaatgaaa aataattata taaatagat
//
LOCUS       DAYAKB010000116         9143 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.117, whole genome shotgun sequence.
ACCESSION   DAYAKB010000116 DAYAKB010000000
VERSION     DAYAKB010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.117"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..329)
                     /locus_tag="ACGI3L_003415"
     CDS             complement(<1..329)
                     /locus_tag="ACGI3L_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9199107.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKS"
     gene            complement(353..994)
                     /locus_tag="ACGI3L_003416"
     CDS             complement(353..994)
                     /locus_tag="ACGI3L_003416"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFG9199108.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            complement(1196..1609)
                     /locus_tag="ACGI3L_003417"
     CDS             complement(1196..1609)
                     /locus_tag="ACGI3L_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HFG9199109.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            complement(1760..2101)
                     /locus_tag="ACGI3L_003418"
     CDS             complement(1760..2101)
                     /locus_tag="ACGI3L_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFG9199110.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            complement(2395..3054)
                     /locus_tag="ACGI3L_003419"
     CDS             complement(2395..3054)
                     /locus_tag="ACGI3L_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFG9199111.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            complement(3585..3962)
                     /locus_tag="ACGI3L_003420"
     CDS             complement(3585..3962)
                     /locus_tag="ACGI3L_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199112.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            complement(4149..5120)
                     /locus_tag="ACGI3L_003421"
     CDS             complement(4149..5120)
                     /locus_tag="ACGI3L_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9199113.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            complement(5154..5351)
                     /locus_tag="ACGI3L_003422"
     CDS             complement(5154..5351)
                     /locus_tag="ACGI3L_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HFG9199114.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILSLYIKQLGVTDVSLI
                     QQYSGIVFGCTFVVAAFFSPI"
     gene            complement(5419..6630)
                     /locus_tag="ACGI3L_003423"
     CDS             complement(5419..6630)
                     /locus_tag="ACGI3L_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HFG9199115.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKYNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6911..7513
                     /locus_tag="ACGI3L_003424"
     CDS             6911..7513
                     /locus_tag="ACGI3L_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9199116.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPTLWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDNSIEVDNC"
     gene            complement(7769..8740)
                     /locus_tag="ACGI3L_003425"
     CDS             complement(7769..8740)
                     /locus_tag="ACGI3L_003425"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HFG9199117.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(8766..>9143)
                     /locus_tag="ACGI3L_003426"
     CDS             complement(8766..>9143)
                     /locus_tag="ACGI3L_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH32 C-terminal domain-containing protein"
                     /protein_id="HFG9199118.1"
                     /translation="YELNINIKNIDSNKFGLELFSSQDEGVKLEFNKLGNIVTLDRSN
                     FKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFINEGEVVFTSRIFAKENSNQI
                     RVYSDKIVEYEYTKFKLKQGIEL"
BASE COUNT         3195 a         1430 c          896 g         3622 t
ORIGIN      
        1 gatttatcat ttttagtgta tactttgtgg tcattttctt cttcaatctt atattccaaa
       61 tttctacttt caaaatacga aataaggtct ttatttgtaa atgtataaaa actactatag
      121 agaaattttt tattactgac aactttatca aaaaaatctt ctatctctct attattggta
      181 aaattgcatc taccgccacc agttgcccta agttttcttc ctaattctcc atttctctca
      241 actaatatta cttcattatt gttttttgaa gctgacaaag ctgccatcat tccagaagct
      301 cctccaccaa ctactataac tttactcata aatttctcct tataattgat tcctactcca
      361 gtgcagaatt atttatcttt acatgatttt ttatatgact tgtatcattc atttttacta
      421 taacaggccc ataatcttta aattctacta tatttaaagc agtattatct tgcttaattc
      481 tatatatatt ttccatacct gattctaaaa atgacaacaa cataaccctc aatgtaattg
      541 aatgtgtaac aagaattata tttttattat catatttttc atttagttcc tttataaaag
      601 catctactct ttcctttata atcttaagag tttcgccttc tggtatattt actaagtgtg
      661 gttcatttct ccatgttgca tatatatctg aataatcttt ttgaatttct tttattaaaa
      721 ggccttccca aactccgaat cccatttctc taagtgcctc agttttttga acttcaatat
      781 tgagcttatc tcctaaaatt tgagctgttt gcattgctct cccaaggtcg ctactaaaaa
      841 tataatcaat tgaatacttg ccaatatctt cagaaagttc ttttgcctgt tctatacctt
      901 gaggcgtaag gtcagaatta ccatgacctt gtgtttttcc caatatattc caatccgttt
      961 gtccatgtct tactatataa aaagtatttc ccatatgtcc tcctaatata tgcctatttt
     1021 ttattaaata taaattatca cttctcaaaa cttaattata tcatataata ctttactttg
     1081 tttctatttt ataatctaat ctaacatatt atttacaata aatctcattt gtatttctgc
     1141 aaattattgt actgttaaag aatttttcta aatttataaa catatttctc ttatattatt
     1201 tatatacttc ttcaaatctg tattcttgaa ttgaattgac atacttatct gtatctactt
     1261 tttctaaaaa catatccaaa ggtcttgcaa atattcctgt atcatcatat aaggtcttgt
     1321 ataaaactaa atcattagta tcttcttctt ttttatgata aaagtttcca tctaaatccc
     1381 tataaacata gatatcttct tctctttcag tatgtctaat aactaattta tatttatttc
     1441 tgttttggat taaattttct ttaccatata tttcacatat gttttctata tcatcaatag
     1501 ccttgctaag acccattgta gcataatatt tccctttgaa atgtttatag atacaaggat
     1561 attttaactt tctttcactg atacctaagt tattctttaa ttcaagcatt ttattataat
     1621 ctcccatatc tcgtcccttt cttttaaaaa gtattttatt ctgaaataag ttacttgttt
     1681 tatattttat cataatttaa aatttattaa taatacaatc aataaataaa gaggctgtat
     1741 aaaatacagc ctcccaatat taatcttcat aatcatataa tttttctaat ttctttttta
     1801 atttcttttt tctttctgaa cctaaaattc ttataaaatt attattcaca aaaatacaat
     1861 tattgctgag ataaaattca cacttgtcta gatttacaat ataactatta ctgcatttga
     1921 aaaaattttc ttctttcaat agttttctta tacaaggagc attttctcca acttcataat
     1981 taccactttc agtataaatc tttacttcat actcttgctt ttctatgtac aaaacttctt
     2041 tactattaat tgaaaaacgt ttatcctcgt attcaacatt aataaaattt tcctctttca
     2101 tttccatccc tccaagtact tttattaatt taattttagt gttttttatc aatataatct
     2161 atcggaaata tatgtaagac tgatttactt aagatattta aataattatt attaatatta
     2221 atgtataagt ttatttttta acattaattt ttaaagttaa aaagactttt tttaattata
     2281 tccgtatata taagtatatc tatctttaat aaaataactt ttatagaaat tcatgtaaaa
     2341 ttatacataa aaaagtaatt attaactttt aatttaaatg aatcgtatta aaatttatct
     2401 tattttccta attttaatct taagtattat atgtattaat acaaagattg aaatgttaga
     2461 taatattaat agtaaaacta ttactaaaaa agcagttctt ctttcaggag agatttttac
     2521 aagattaata atataatcat aaagtacaaa aaatgacaat aaatttgcta tcataggaat
     2581 acatatgtat atctcttttt tacttatttt aaaattttta aaagaagcct tataaacata
     2641 aagtaatata cctaacatta tctttcccaa gaatattgct tcatatctat ataaactgcc
     2701 actaagtaaa acattcatat tatccaaatt gcttactgtt gctactaata acatacttaa
     2761 tccatttata cctattaata ttaaccaata aaaaaatgag attaccagac atttatatat
     2821 attaacctta tagttagact tatagaaaac gaacattaca aatatacata tcaagattct
     2881 actattagct cctatattta tatataaaga agaaataatg agaaaaacag aaaagagaaa
     2941 atacatattt agttttttta agtcggtctt tgactgacta gtataatcaa aaactttttt
     3001 acatgaccat atttctataa tagaagaaac aattgttata aatgcatcta acataataat
     3061 atcctcaaaa atgattaaat tatatttttt ataaaatata tcataaaaaa tacatactaa
     3121 ttatagcata aaaaacacac ttaaatttaa tataattatt taatattttt aacaactttc
     3181 tatagtacat tttaaaatat ttacagataa gttaccaata ataaagttta aaaatataaa
     3241 aatcatttct tacttttagt ttacctataa taacaaaaga caggtttata ttgtaataat
     3301 taaaaatagt aaaatatatt ttgatatggt taaatagaaa taatacttta gattaatgaa
     3361 tattgacaag ttataaaatt attttaaatt ttaaaaatca tttcttattt aaataagtgg
     3421 tatcatttaa cttgatactc cctattccaa ttattttagg cattttacta attagagaac
     3481 ctatttaata ttactttatg aatagtgagt agctgattaa ataataccat ttatggtttt
     3541 cagccataga ttaattaaat tcttagagtt ctatcctgat ataattactc ttcttctaaa
     3601 tttttaaaat gactttcaaa taaatccaac atatctttat caacaacttc atcatcatgt
     3661 agtgctgaaa ttaaactctg taaagaattg tcgtgtatat tgcttaaaaa atcttttgtc
     3721 tcaacactta aatactcctt atgtccaaca actattgtat aatgagtgta tctatctatt
     3781 ttttctgcac ttaaaaaatg ttttttaaca agtcttgata aaagtgtcaa tgtagttgtt
     3841 tgtttccaac catattttcg ttccatagct tcaatagttt cttttgatgt tactgtatca
     3901 tttttttccc aaataaactt cataactttt aattctgctt gtggtatttt tgaaattgtc
     3961 ataaccttac gcccctctca aacttttatt aaattaatac tatcgcaata tagtttttaa
     4021 gtcaaagatt ttgtcgataa taatattttc caatttttac catagggtta ttttttatat
     4081 aattctatga taaattacat aaaaaatatt tattttacat cataaaatta gaaatgtaaa
     4141 tagtatgatt atttagtctt atctttaata aacaatccag taaatttata catccaaagt
     4201 gcattcataa acaacaataa acttgttgaa aaaaatactg ttctaatacc taaatgtgct
     4261 gatatttgtc cccctaaaaa tgctcctgat gaacagccta tatactgggc agatgcatta
     4321 tatccaaata tttttcccac atattcttct ggtgcaattt ttttaagcaa gctgttaaca
     4381 gaaggattaa gccctgcaac tgacaaccct aataaaaatc tcaacaacat cagttgccat
     4441 gcagttttta caaaagcttg tggtataaat ataatcccag cccataaaag tgaaattaac
     4501 aatacttttt gaggacctat tttatccgac atttttccaa gtttttgagc tgctaataaa
     4561 tttgctaatc ctgatgcaga aaatgtcaat ccagctatta aagctacatt tgatgcaaaa
     4621 tttgtaagtt gtgatatata tatggttaca attggttcta tagagtataa agctagttga
     4681 gtaatgaatg tggttacaaa aatagatgca attaaaaatt tatttggcaa tatatttaat
     4741 tgttctttag gtatagaaat tgattctttt atttctttag gtttaaaatt atctactaca
     4801 aataaaatag agatgataaa tgatacaaac aacaatcctc ctgttataat aaatgtactt
     4861 ttaagaccta agattgattc tatatatcct cctactgttg gaccaattaa tgagccagta
     4921 gttgatgcag ttgcaagagt acccaaagcc catcctgaat gatttttatc tgtctgtgtt
     4981 gcaataagag tagtacatgc agtagcataa cccgtaaaaa ctccttgaag tattcttaat
     5041 cctaataact gatagacatt ttgaacaaac gccatggtaa atataactat tcccatccca
     5101 atacttgcac gtaaaagcat tgattttctt ccatatttat cagcagcttt ccctcaaatt
     5161 ggcgaaaaga atgctgctac tacaaaggta catccaaaaa ctatacctga atactgttgt
     5221 attaaactaa catcagttac ccccaactgt ttaatatata atgaaagtat aggtgctatt
     5281 tggctcatcc ctatagaact aaaaaacata cctatccaac atacaaataa atttcttttc
     5341 cacaattcca tatagaatta caccccctgc attttaaatt ttttcaataa tactaagttt
     5401 attaatttat gctattgttt actcaatata tccatctttt cttttataat attgtttagg
     5461 aaattcataa cttgaaaata atagcggtga taaagaatag gagtaacttc cagcattact
     5521 aattgaaatc aaatctccta tgtttgcttt tttcaattta acattatttg caattacatc
     5581 taatgatgta cagagattcc caacaacatt tacatactct tcttctttta aattatttaa
     5641 tactgaaaga gaaaaggcat gatttgatgt atataatggc tcttgacctt ctaattctac
     5701 tccacaagta atattttcaa ttaaattaga aataataggt ctcataaatc cattaagtcc
     5761 attttttaca ataagatatt ttttccctct tgatacttta atatctacaa ttttaacata
     5821 ataattacct gatttacaaa ctatgaaacg tcctgattca ataagaagtc ttgattttag
     5881 tgtgtttgaa ttagtaaaag caatcttttg agttaatttt gaaagctctt taagattaag
     5941 tggattttct ctaagattat cataagctac tccaagtcca ctaccaaaat ttataaattc
     6001 aatattaata tacttacttt tatttaaatt taaagctata aaaaaacatt tttcataata
     6061 atgtcctaac ttttcaaaat ccaatacctg agatttaata tgtatatgaa tcccaactac
     6121 agatacataa tcacacatac ttaacatctt aaaaacactg ctcatatctt ctatatctat
     6181 accaaatttg cttgatttag cactatcatc atccatagta aaatcaggat ttattcttat
     6241 tcctatttta actttctgat tatacttttt agatatctta tttataagtt ctatttctgt
     6301 aatactatct gcaataatta tgcatttatc taaaacagtt tctatatcaa tctctgtttt
     6361 gcctggtgat gaataataaa tatcatcttt agaaactcca cattctgatg aaatcataac
     6421 ttcattagtt gaagaagcat ctgctccaaa accttgctct gcaatgcttt ttacaatttt
     6481 gttatatgga tttgttttta tagaatataa aaaatcaaaa cctaaaatat tatttttcaa
     6541 ttccttacat ttttcaatta tattagtctc atcatatata taacatggtg cattttcttc
     6601 tataaattta tagtcttcat ttgagtacat attttttacc tccaagattt taaatataat
     6661 cataaattaa gcaattataa tcctataaga taattttaca ataaattacc atagttaact
     6721 acacacatat atgtaaaaac atacctaaaa tatttttaat tatagataca ttccaacttt
     6781 tattgataaa acaatttgtt tcaattttat tacaaatata caaagtgtat tgttgttaac
     6841 gtattctcat agtatcctaa aactatatta agcactaaaa actattttaa aatactgtgg
     6901 aggtatcaat atggaagtat gcattcttat gggaagtcct aagaaaaaag gtaatactgc
     6961 tgctatttta aaacctttta ttgaggaatt agaaaattat aattcaaata ttgaagtaat
     7021 atggttatat gattgtaaaa tagagccatg tattgcttgt aaaaaatgtc aggataactt
     7081 atttgatttt ggatgttatt gtaaagatga tgttcagaaa attttcaaga aaattcttat
     7141 gtgtgattta attgtttttg ctactccaat ttattcttgg tactgcactt ctccaatgaa
     7201 agcactactt gatagattgg tgtatggaat gaataaatac tatggtaatg agaaaggccc
     7261 cactctatgg gcaggaaaac cagtagcact tattacaaca tgtggatata gacctgaaaa
     7321 gggtgctgat atttgggaaa atggtatgaa gcgctactgt aagcattcac agttaaaata
     7381 tataggaatg cttgttgaac gtgatttagg taaacctaat tttatgaata aagaaaaaga
     7441 agaacattct cgtcaatttg caaaacaaat ttattatatt ttagataatt caattgaagt
     7501 agataactgc taaagacata atactccaag taaagtattg ataatataaa taaatcttac
     7561 ataatttgct tatttaaaat aagatatata ttcttctaaa aagtaacaat aattaaaata
     7621 ttttttatca tttcaacaat gataaagagg cttatctcta ttttgagaca gcctctttat
     7681 tgctttttat atgttaatta ttttcatagt aaacatcctt aaaaactctt tacatgttac
     7741 ttccttcaaa acctattact cattcctact ataaattttt tataaattca gttatttctt
     7801 cctttgttgc atatgaactt atcgcacctt taatagttgt actacgagct gcataataat
     7861 tagaaaattc taaatactca tttaacgttt cttgtttcat ttcttttata tcattcaatg
     7921 ttatttgttt atacaataag gtgtataaaa atgaacctat ataagaatct cctgctccgg
     7981 ttgtatctat tgcatttact ttaacccctt tacacatacc ttttactttt ttagtgtatg
     8041 catctactcc atcttttcct tttgtatata atactagttc aacattcccc acaaagagtt
     8101 tatgtaatga tttttctata tcattttctc ctgttataaa ttctaattct tcatcagata
     8161 tcttaacaat atgagcaaaa ggtaaaaatt ctgatattgc ctttttacaa gattgctcac
     8221 tatcccataa aggtaatctt atattagggt caaagcttat tatactatta ctttcaagtg
     8281 cgtattctat tgctttttta tgtgctaatt tcattggact atctattaaa tctactgaac
     8341 aaaaatgtag gatatgacaa ttattaaacc actctttttt aacttcatca gcttctaaaa
     8401 gcatatctgc acttggattt ctataaaatg agaaatcacg attaccatct tcttttaatg
     8461 atacaaaagc aagtcctgta tttgctttac ttgttctcaa tacataatca gtatttacat
     8521 ttacttcatt taatacatct attatataat caccaaatgc atcttttcct aacttagata
     8581 taaaactcga ttttcctcca agctttgcta caacagcact aacatttgct ggagctcctc
     8641 ctgctactct tctaaattct gatacatttt ttaatttacc accattttga ttcggtataa
     8701 agtctattaa agcttctcct atgctaatta cttttttcat cttttctacc ccttataatg
     8761 tgtttttata attcaatacc ttgctttaat ttaaatttag tatactcata ctctactatt
     8821 ttatcactat aaacccttat ttgattagaa ttttctttag caaatattct actagtaaat
     8881 actacttctc cttcatttat aaaaatttct aaaatacttc tatccgctag tactttgata
     8941 ttagtatttt catcaatatt tatatattct tttctatttg ttccatattc aacaccgaaa
     9001 acttttttaa agttgcttct gtctaaagtt acaatgtttc ctaatttgtt aaattctaat
     9061 tttacacctt catcttgtga tgaaaataat tccagcccaa atttattgct gtcaatattt
     9121 tttatattaa tattaagctc ata
//
LOCUS       DAYAKB010000117         8784 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.118, whole genome shotgun sequence.
ACCESSION   DAYAKB010000117 DAYAKB010000000
VERSION     DAYAKB010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8784
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.118"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..205)
                     /locus_tag="ACGI3L_003427"
     CDS             complement(<1..205)
                     /locus_tag="ACGI3L_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199119.1"
                     /translation="MQQKCKKKALSMILSISMGLGPVASFNASNTFADTIEESTNAGN
                     AEGGTNAGNAEGDTNAGDAEGDTN"
     gene            474..1046
                     /locus_tag="ACGI3L_003428"
     CDS             474..1046
                     /locus_tag="ACGI3L_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HFG9199120.1"
                     /translation="MKKLVKILINIICIITLIFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEAFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNSNYEFKDYLNYIT"
     gene            complement(2059..2721)
                     /locus_tag="ACGI3L_003429"
     CDS             complement(2059..2721)
                     /locus_tag="ACGI3L_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199121.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(2738..5293)
                     /locus_tag="ACGI3L_003430"
     CDS             complement(2738..5293)
                     /locus_tag="ACGI3L_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9199122.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPHDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKNDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLLRLMGAKKRNIRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGMISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLISVVVSNRDFESMNIIEGIKENE"
     gene            complement(5533..5721)
                     /locus_tag="ACGI3L_003431"
     CDS             complement(5533..5721)
                     /locus_tag="ACGI3L_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HFG9199123.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTK"
     gene            complement(5733..5912)
                     /locus_tag="ACGI3L_003432"
     CDS             complement(5733..5912)
                     /locus_tag="ACGI3L_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199124.1"
                     /translation="MIHIEISEKEFFRKIEEVFDKGEVNVEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(5917..6174)
                     /locus_tag="ACGI3L_003433"
     CDS             complement(5917..6174)
                     /locus_tag="ACGI3L_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199125.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSITKEKKDTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            complement(6554..6760)
                     /locus_tag="ACGI3L_003434"
     CDS             complement(6554..6760)
                     /locus_tag="ACGI3L_003434"
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9199126.1"
                     /translation="MCKYLDNAIEACDKIHDKSIDKYIQIKGTISKSYFVIKCENSKI
                     NSIRKNKSLLLTDKKDKLVHGIGI"
     gene            complement(6936..7181)
                     /locus_tag="ACGI3L_003435"
     CDS             complement(6936..7181)
                     /locus_tag="ACGI3L_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFG9199127.1"
                     /translation="MIPRLILASSLVIIIVFIKIIKENKLKLQNEVIKNKLDMQYSHY
                     LSIQESHAKVKKLYHDINNHIYCIENLKYKKGKLMGM"
     gene            complement(7821..8144)
                     /locus_tag="ACGI3L_003436"
     CDS             complement(7821..8144)
                     /locus_tag="ACGI3L_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9199128.1"
                     /translation="MKKIKINLTHTKSNLAKKYIEVQKKNMLIHTKNKTLDAICILEK
                     IEKDLNIEELVRCHKSYITNLNYVENIKSNTAILDSQEEVPISRYRYKDIKEGFLKFI
                     GDRIC"
     gene            complement(8383..8535)
                     /locus_tag="ACGI3L_003437"
     CDS             complement(8383..8535)
                     /locus_tag="ACGI3L_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199129.1"
                     /translation="MKNLNKNTILGEVIITITACDDEKEIQIVIKNQVDNILKNKNKE
                     YRIKKI"
BASE COUNT         2929 a         1287 c          903 g         3665 t
ORIGIN      
        1 cattagtatc tccttctgca tctcctgcat tagtatctcc ttctgcattt cctgcattag
       61 tacctccttc tgcatttcct gcattagtac tttcttctat agtatctgcg aaagtatttg
      121 acgcattaaa tgatgctact ggtccaagtc ccattgagat acttaaaatc attgatagtg
      181 ctttcttttt acatttttgt tgcataaact ccccctcccc ttaataattt ttaatataca
      241 ctgtatacat ccttatatac actctaataa ttcttaatat acgctgtata cattctaatg
      301 cacactctaa taatttttaa tatatactta aaacttatat ttgtcaatga atatactgtt
      361 ttttcaacct tatatattat aagtattcat tatttgctaa ataactacaa taaaaatttt
      421 aattatataa aatttattta attttttata taataatact aaggggtaat taattgaaaa
      481 aactagtaaa aatattaata aatattattt gcattattac gctaattttc tctagccttt
      541 cgatttacat aaaattatct gaatataaaa aagctgatga agtatatacg gaactcagag
      601 aaaacactat caataatagc aaacatcaag aactttatga taaaaataat gattatagat
      661 tctggcttaa aataaacaac gtaaatatag actatcctgt agtacaagga tataacaatg
      721 atttctacct aactcatgat ttttataaaa attatcttcc tttaggtagt attttcatgg
      781 attatagaaa taattttgaa aatgataaga gtttaatagt ctatggtcat tatatgaaaa
      841 ataaaactat gtttggtcag ctagaaaact atactgatga agcatttttc aaagaaaata
      901 acttagtaga aataaattat aaagtacaaa cttatactta tgaaattttt tcagtatata
      961 ctgctgactt aattaacaga gattatttaa gtatacactt taatagtaat tatgagttta
     1021 aagattattt gaattatata acctaaaaat cagtacacaa atctgatata aaggtagata
     1081 tttcagataa aattataact ttgtatactt gtaactatga atttaaagat gctcgtacta
     1141 tagttcatgc taaattaatt tcaaaaaaag agactgataa gtaggtttgt gtaaatgcag
     1201 acttacctac agtctttttt gaacgtaaaa ttagtaagta tggaataata ttcatattaa
     1261 acttttgtag gcaaagaaat gaaaaatcaa agagaaataa ttattacaga tttagattac
     1321 caagctgaat taagaaagtg taaaactatg gaggatgtag ttggtgaaga tagtatataa
     1381 tagtttaact tataaattat cttggtgata ttaatgaagt ttcaaagtat atattattta
     1441 ttgatataaa taatattaaa tctgttgcta acagatgtac ctttgtttgg agacaaacta
     1501 tttaagaaat ataactaaaa tgttgaagta gctacctgac tttattttga aatgcgaaca
     1561 agattttggc attaagataa tttagaaaga atcactggta cacaaggatg tgaacttaga
     1621 atgaatagaa gtattcaggc ataaggagct ttcacccaaa taaaacatag tatgaacttt
     1681 aaaagaattc taatcagagg caatcaaaat gttctttcat agtttatacc tgtagtgtta
     1741 gacatagtat ttataagttt cacaaataag ataatcatta ataaatgtag tatgtatatt
     1801 catcctctca aaaatatttt ttaatcttac actttgtaaa ttattctatt ttaaaatggt
     1861 atttttatac ctttatttct tatgaccgtt ttcaagctca aattttgcat aaatataaat
     1921 taatgaaaag caagtaaaaa aagaactgtc gcacagcaat ttaaaattac tcattcgaca
     1981 gtccttattt cgtggattta aatagtggag aagaatcaca agaataatac ccacgattaa
     2041 acctttatac aatacatttt atatgacttt accatcacta atagttatta tacaatcagc
     2101 catcttagct atttcatcat tatgagttat cataaccaac gtctgcttgt attcatttac
     2161 acaatacttt agtaaattca tcacctcatt agttgtttta ctgtctaaat ttccagtagg
     2221 ttcatctgca aaaattattg atggcttatt ggcaagtgat cttgctattg caactctttg
     2281 ttgttgacca cctgataatt cattaggaaa tttattaatc tgactttcta atcctaactt
     2341 agttattaaa tcattaatat aattattatc tatctttcct ttagcaatta aaataggaag
     2401 aactatatta tcataaacat tgataacagg tattagatta tagttttgga atataaaccc
     2461 aaattcttta cttctaagat tagatagctt ttcatcactt aaagtatata aatctaaatt
     2521 atccataaat acattaccta aagttggttt atcaagccct gccatacagt gaagtaatgt
     2581 gctttttcca gaaccacttt gtccaattat tgcactaaat ttatggggtt ctatctctaa
     2641 agtaattcca tcaacagcct ttatttcatt ttctcctttt ccatatattt ttttaatatc
     2701 tataactttt aacatcttca tacatttacc tcccaaatta ttcattctct tttatacctt
     2761 caataatatt catactttca aaatctctat tacttacaac tactgatatt aaacatacaa
     2821 atacagatat agcaaagaat agtaaagatt ccttaattgg gaatgtaaaa gacataaaat
     2881 tctctattcc atagtttata tacgcatcat tattccaatt tgtaaattta actagattta
     2941 taaatgatgg aatcatagct attataaagc taaaaactgc atatgctaat gcttcatata
     3001 taagcatttt tttcatattt ttaagactaa cacctaatgc tctaagcgtt gaaatttctt
     3061 tttttctaat tagtagattt gttcttatag tacagaaaat attaattgat gctattatta
     3121 aaactagtgc aattattgct atttgtgatt taatgtaact tttatatata ctttctgaca
     3181 tttcatgata acttaatcta ctattaaata gagaccctgg tatacttctt gaaattttct
     3241 gtatctcatt attaacaatc tcatcatatg gattttctaa atttatgcct aattgagtgt
     3301 atttttgttc tcctgttatg tttttagagt gaatattact tgttataatt tctagatctg
     3361 gcataaaatc gccatctccc atagcaatcc attcatcctt taaaattaca gccactctta
     3421 ccttcatctc tttataaaca attgtattat tttcttcaac aggaattttt acagttatta
     3481 tgtctcctat atttaattct ttgaatatag gctttatagt atgatcatca actatatcat
     3541 aaaaataatt atatactgct acatttggat atccatcagt gtccttttta atatcatcta
     3601 agctaccttc ttcaacaaag tcatttaact tttcatctat ataatcatca tcataaagct
     3661 ttaaaactaa tttatcttcc attatctctt ttttttctac tccattatag gttgtaaatt
     3721 ctttgtttat atccttatta ttaaaagtaa acattccatt tgttatttga attttatgta
     3781 tacttttaac acccttaatt ttttctatat tctctacatc actatctgtg tattttgata
     3841 tttgcgggtc tgcatttact ccaaattgca ttgttatatt atatctattt tgcatatctt
     3901 caattttact gttgacctct tcttgcatac ttgagaatgt agtaatgaat atatatcctc
     3961 ctaaagcaat agacaacata gatatagcag ctctaacctt atttcttccg atatttttaa
     4021 gtcccataaa tccataaaat ccaaatattt tgcttactag tctgtctatt ccaagtctac
     4081 ttctgtgatt tttaattttg tctgtattta ttattgattc aataggtgat atcttgccga
     4141 ttttaaaagt tggtataata caagatataa aaacagaaat cattccaacc aatatagctt
     4201 ttataactat ttcattattt atatataatt tagggttaag accagcttca ctgtataaaa
     4261 cttcgttata attactaatt cctatatatg aatatgtaac cccagctact aacccaagta
     4321 gtatacctat tattgttata attaatgctt gatagattat catacacctt atgtttcttt
     4381 tctttgcgcc catcagtcta agcagtccca tttcttttac tgattgattt agtgtaatat
     4441 tgaaaatatt aaatatgaaa attatagata ctgtagttat taaaacattt cttttaaaaa
     4501 cattcggatc attcttatca tcttctacat aacgaagttc ccttacaaga ggtacatttg
     4561 gtagaaaact tttttgtccc aacttatatt ttttcataag ataatcacat tcaccttcaa
     4621 tatttctcca tccactttta aaacttaata tactattata actaatcgca tcatgaggta
     4681 taatgttatt tgtttcatca ttgccataag ttactgcttc gtattgccaa accacatcat
     4741 agtacccttt tggtttttcc ataactccta ctattttaaa ttctttattt atagaaaata
     4801 attgattact tccgttagta tctttatagt tcttttttat tgttaaattt aatgtagatc
     4861 ctactccttc acttaaattc attgcttcta gtgctttttt ctctaatact atttcattgt
     4921 tgtttttagg tagtctacct tctattattt tgttgtatct actttttaga tactcttcgt
     4981 ttgatgaagt taatataaat gagtttcctt ttttatctga aatacgtcct agattttgta
     5041 ccgaattacc ctttgatact ttttcatcag tttctaattt tttagcatca tcaagtgtca
     5101 aatcactaaa ctctacatgg tatccactgt aaagttcatg tattgctact acattgtttt
     5161 cattttgtga atcttttata acactaggtc caaatatcaa cataacacct aacataactc
     5221 ctattattaa aagtaatgtt ctaagtttat ttttctttaa atatgctagt gacattttta
     5281 agtaaatccc catataatcc tcctatttta ctataaatta tttatccaac tcatctgtta
     5341 agtagattgg tggatatttt aaatctttta attcttcatt attttttgaa gcttactacc
     5401 atcttcctca tgataaactt gcagtatcac cttatttaca tgtagtgcat aataatcacc
     5461 attataaaaa tattagtatt tataacctgg ataatttttg taaaatgatt tataaagtat
     5521 cccatcctaa ttctattttg tatacttttc ttttgtaata cgctctatat catcacctga
     5581 aactccttga tatgtcatat atttatctat atatttttca gcttcattcc attttctaaa
     5641 atagttgttg tatataataa atcctattat ggctataatg cttataatta aagttaataa
     5701 aatagctttg tattttctca tagtgaatct tcctacttca atttaaattc tttaataagt
     5761 tttaattcta aagacttagt tttatcatca aatttcttaa cttgaatttt tatatctccc
     5821 aaattatcaa cctctacatt tacttcacct ttatcaaata cttcttcaat ttttctaaaa
     5881 aattctttct cacttatttc tatatgaatc aatgatctat atgttataaa tggccattat
     5941 gaatttatca tcttctgaca gcttttcatt ataagaaaaa tctttaacac attgaattga
     6001 taatatttcc ttcgtatcct tcttttcctt agttattgaa taatgtaaaa cttggctagg
     6061 ttgttctttt gtatactcca agtttcccaa agacaaaaca aaacttccat ctgatttatt
     6121 ttcagctacc ctaagaccac tattttctat tgattctgat attttctttg acaagtcttc
     6181 ttgatactag aaatctgttc aatagtatat attttttcat ttgtacctga aaccttattt
     6241 gtgcatcctg ttattaaacc tagtgttaag cttatagcta taaccatagt tattgtaatt
     6301 tttttatctt catataatcc tccttatata ttgaaaactc gttatttctc ataaaaaaaa
     6361 gacgctatct ttttctatta aaagataaca tccctatatg tttagtatca atatatgttc
     6421 cccaactggt aggttaatcg acccaactat caaaattttg atttaatggt atataaatat
     6481 tcaatataaa tttgtctttt ttatcttcaa atgataaatc tcctctatat ttttttatag
     6541 aagatttgat gctttaaatc cctattccat gtacaagttt atctttttta tctgttaata
     6601 ataaactttt attctttcta attgaattta ttttactatt ctcacattta attacgaaat
     6661 aggactttga gatagttcct tttatttgta tatatttatc aatactttta tcatgtatct
     6721 tatcgcaagc ttctattgca ttatctaagt atttgcaaat atattagata catctattgg
     6781 ttttataaaa ttcactttgg aaaaattgat atcacaaatg aatttaattt ttcttttttc
     6841 acttacatca cttttttcat ttattattat atccaatata acattacctg tattgtaaat
     6901 tgatttaaat tctttaattt aatcttttaa actatttaca tacccatcaa ttttcctttt
     6961 ttatatttga gattttctat acaatatata tgattattta tatcatgata aagcttctta
     7021 actttagcgt gtgattcttg aatacttaga taatgagaat actgcatatc taacttattt
     7081 tttattactt cattttgcaa ttttaactta ttttccttaa ttatttttat aaacactata
     7141 ataatgacta agctactagc tagtattaac ctaggtatca caatataccc aactatatat
     7201 atttcctaat acccaccaaa tcgatacatt tttctattta tataaattat taatatagta
     7261 aataaatttg ttattaaagc aacagataag tatatatagt ttattttatt atctttatct
     7321 agtcccaatc ttttattaat aaatttaaat atagcacaag ctactatata actattatta
     7381 taagataata gtatatatct actttagcat tatcataact aaacactaat agagcttcct
     7441 ctgatgatat tacattactt gtaactacaa aaaataaatt tatagatata acatctttta
     7501 ttaaagggtg atatacgtca aataagaaaa atgaaactat atatttaaca attcctatct
     7561 tataaaaata attatagtaa gttcccaagt aataaatatc aaataataga ttatatcata
     7621 tagatttttc ttcatattat aatcatgggt cttatcaaca ttaaataata taatgatctt
     7681 agttataaga taagctaata atacagtaaa aaaagatatt ttcttagtct tatctgtatc
     7741 tttatcgtaa gttaatatac tttttagtat cattattggt gtaaacaatg ataatattaa
     7801 taatatttta tttatatggt ttaacatatt ctatcaccaa taaattttag aaacccctct
     7861 tttatatctt tatatctata tctactaata ggtacttctt cttgactgtc taatattgca
     7921 gtatttgact ttatattttc tacatagttt aagttagtta tataactttt atgacatctt
     7981 acaagttcct ctatatttaa atctttttct attttttcta ggatacatat agcatcaaga
     8041 gttttatttt ttgtatgtat tagcatgttc tttttttgaa cttctatata tttttttgct
     8101 agattagatt ttgtatgtgt tagatttatt tttatttttt tcaatttttt tggtacatgt
     8161 taatatgtgt ttttctagtt cttgaaaatt tattggcttt aataagtatc aataagctct
     8221 tacttcatat ctttcctgta cataatttat tagagatgtt ataaatatta ttatctactt
     8281 ttcttatgtt tcttgcgata tctatactat ttagttctgc catttttata tctaagagta
     8341 gtgtatcctc tcaattaact ttgtaatgat tcttcttttg agctatattt ttttaattcg
     8401 atattctttg tttttatttt ttaatatatt atcaacttga ttttttatta cgatttgtat
     8461 ttctttttca tcatcacaag ctgttattgt aatgataacc tctcctaata ttgtattttt
     8521 atttagattc ttcactttag gttaaaactt tttaaatgta tttatcaata atatttaaat
     8581 taaaaatgta taaaaatacc tatatccaat tggatatagg tattcgtgga tttcaatggt
     8641 ggagacgagg ggagtctata agtggttatt tgattgtttt gttgtttttt gcaagtgtag
     8701 gtatatagct atttagttat gatgttaaac tgattttttc ggatattttt tattgtttat
     8761 ttttgtagtt ggggtattat tggg
//
LOCUS       DAYAKB010000118         8528 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.119, whole genome shotgun sequence.
ACCESSION   DAYAKB010000118 DAYAKB010000000
VERSION     DAYAKB010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8528
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.119"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..411
                     /locus_tag="ACGI3L_003438"
     CDS             <1..411
                     /locus_tag="ACGI3L_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HFG9199130.1"
                     /translation="GGSNMADKIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASY
                     FISKNKSKNKNHSLINPILNAQNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIV
                     GYEVEEKKVNRDLLIGGYLYYNLIYTKSEENENE"
     gene            404..1393
                     /locus_tag="ACGI3L_003439"
     CDS             404..1393
                     /locus_tag="ACGI3L_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I CRISPR-associated protein Cas7"
                     /protein_id="HFG9199131.1"
                     /translation="MNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALKFP
                     MKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEDLKLEKNQQKVL
                     ENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPKAK
                     DKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKNDY
                     KKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDLIC
                     INIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV"
     gene            1395..2135
                     /gene="cas5b"
                     /locus_tag="ACGI3L_003440"
     CDS             1395..2135
                     /gene="cas5b"
                     /locus_tag="ACGI3L_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5b"
                     /protein_id="HFG9199132.1"
                     /translation="MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACL
                     GLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGN
                     LIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEII
                     TDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYKEPFKYQEKLPYRLHRMTNQYILE
                     TIIFTNMSVKLINKKEVYQVKGLNLIFI"
     gene            2159..4717
                     /locus_tag="ACGI3L_003441"
     CDS             2159..4717
                     /locus_tag="ACGI3L_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HFG9199133.1"
                     /translation="MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSY
                     LMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKM
                     QNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHG
                     VLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEAYLDDSHI
                     KDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDDFGTIDNYNKYYDVLKKSEIY
                     KGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKT
                     VTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSI
                     TPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSRE
                     ECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLG
                     CNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKIL
                     IEFIKKSSALKFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQ
                     VVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVR
                     KERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFT
                     EVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKM
                     SEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL"
     repeat_region   4842..7841
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4907..4936
                     /rpt_unit_seq="gttaaacagtaacatgagatgtatttaaat"
     gene            7926..8420
                     /locus_tag="ACGI3L_003442"
     CDS             7926..8420
                     /locus_tag="ACGI3L_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HFG9199134.1"
                     /translation="MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELK
                     EEKTKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGK
                     IEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYE
                     YCYI"
BASE COUNT         3623 a          784 c         1327 g         2794 t
ORIGIN      
        1 ggaggaagta atatggcaga taaaataaaa gttattagtg aatctttatt tgaaaaaata
       61 aattctataa aaacgaaatg tatacaaagt gatgaagaat attattttgc agttgggcaa
      121 ttagcatcgt attttatatc taaaaataag tcaaaaaata aaaatcattc tctgattaat
      181 cctatactaa atgcacaaaa tagaaaaaaa atcatgttag agatagaaaa attatttaaa
      241 aaatataatt atgatataag ttatgacaac aataggcgat ttaagaatct atattctatg
      301 attgtaggat atgaggtaga agaaaaaaaa gttaatagag atttattaat tggtggatat
      361 ctatattaca atttaatata cacaaaaagt gaggagaatg aaaatgaata gaagagtata
      421 tggagtatta ggtataaaat ctataatgtc aaactggaat gctgattttt ctggatatcc
      481 aaagacgaca tcaacaggag aagtttttgg gagtgataaa gcacttaagt ttcccatgaa
      541 aaaaatgtgg gaaaatgaag gtgaaaaagt tttatatgtt aaatcattaa aaatagatga
      601 atctaagaaa ggagaaataa aaattagacc aaaatcatta aaagagagat atgaagaatt
      661 gtttgatata gaggacctaa aactagaaaa gaatcaacaa aaagtactgg aaaatctatt
      721 taaagctatt gatgttaaaa attttggtgc aacatttgca gaagaaggaa ataatatagg
      781 aattatgggc gcagtacaaa ttggacaagg atttaataag tatgaagata ttaatgttga
      841 agaacaacaa atattatccc catttaggga tccaaaagca aaagataaga aaaagtcaac
      901 aaatgaagaa gaaaaagaag atgcaaattc aactacatta ggaaaaaaaa tagtaagtga
      961 tgaggctcat tacttttatc cattttcaat aaatccaaaa gcttatgaag tttttgttaa
     1021 tatgggtgtg actgatggat atactaaaaa tgattataaa aaatttaaag aagctgcttt
     1081 agtaagtgca actgcattca atacaaattc aaagcttggt tgcgaaaatg aatttgcatt
     1141 atttgttgaa actgatgaag agttatacct accagatttg gcacaatata taacttttga
     1201 aaagagagaa aaatcaaaag atttaatttg tataaatata attcatctta tagcagaatt
     1261 aaaagatgat ataaagagcg ttgagatata ttataaccca tataaaatag aaataaagcc
     1321 ttttaaagat gaaatattac ctaagataga taaagttaaa tttatgaaca tatttacaag
     1381 aaaagaggta taatatggag gttttgaaat ttaacttaag tggaaaaact gcttttttta
     1441 aaaaaccaga tgtaaatagc ataatttatt ttacgtatgg aaacatacat aaaattgcac
     1501 ttatgggtat tttaggagct tgtttaggac ttggtggata taatcaacag agtaaggaag
     1561 atgagtatcc agaattctac tctttactta aggatataaa aatgtcaata gttccaaagc
     1621 atgaatttgg atatataaat aaaaaagtcc atatatttaa taattctgta ggatatgcat
     1681 caaaagaaga aggtggaaat ttaataataa aagaacagtg gcttgaaaat gttagttggg
     1741 atatatatat acaattagaa gattcaacta caagtagaga gcttaaaaga agatttttat
     1801 ctaataaatt tgtatatata ccttacttag gcaaaaacga tcatatagct aatataagtg
     1861 aaatagagat aattactgat ttttacaaaa cagaagatat taacagagtg gacagtttct
     1921 ttataagaga ggattttgag tttgaaaaat cttattttga tgataatgat gattataaag
     1981 agccatttaa atatcaggaa aaacttcctt atagactgca ccgaatgact aatcaatata
     2041 ttttggaaac tatcatattt actaatatgt cagttaaatt gattaataaa aaagaggtat
     2101 atcaagtaaa gggtttaaat ttaatcttta tttaaattta taggtttagg agaattatat
     2161 gtactttaaa aaagttgagt tgtttgatat aagtaataat ataaataatt gcaaaaatat
     2221 ttatgctcat ataaataaag acaggaagcc agaaacttta aaagaacatt cagacttatc
     2281 atactcatat cttatgaaat tatgtgtaaa aaaagattta agctcttgcc tagagagaat
     2341 agagaataaa ttttttaaaa aagattcttt tttaagtaag aatttttata gagagattat
     2401 cttgaatatg gtttatatgc atgatatagg taagattaat tcttcatttc agtttgtaaa
     2461 aatgcaaaat aaaaatttta aaaaaatttc acttagatat actaaacatt cttttatctc
     2521 ttcaatgcta tattttgatt actattttga aaagcttaaa aaatatgatt ttgaagaaaa
     2581 aaaaatattg agtttatttt tgatgataaa tacatataca atatcaaaac atcatggggt
     2641 tctgaagtca tttaaagaat ttttattttt atttaaagat gagtttataa acattaaaga
     2701 aaattttaaa gatttattta aaaacaatta taatttagag cttaaatcag ttcccaaaac
     2761 tatagaaaaa atggtaagag gtgtagaagc gtatttagat gatagccata taaaggataa
     2821 cttagctata gacttatata tatattcaaa attgatgttt tcaattgtta catcttgtga
     2881 tttttatgct acatcagaat ataatagtgg taattctata gatgattttg ggacaattga
     2941 taattataat aagtattatg atgtattaaa aaaatctgaa atatataagg ggatgaaaaa
     3001 atatagggaa tacttaaata acaatagtga atgcccatat aaagagaatg atataaacag
     3061 attgagaaca gaaatgagta tagaagctga agatgcaatt acacataata cgagaaaaag
     3121 aatattttat ttagaagcac caactggaag tggaaaaact gttacatcta taaatctagc
     3181 actgaaatct atagagttaa atcaatcttt aaaaaagata ttttatatat ttccatttaa
     3241 cacattagta gagcaaacaa aagatgtatt tataaatgaa atatttaatt ctgttaaaga
     3301 catacaaaaa gatgttgtag ttataaattc aataacacca atacaaacag aagataaaga
     3361 agaagataat aaaaatgttg aatattgtgt tactaaacaa gaaattgatt atgataaatc
     3421 attgttaaat agacaatttt tacactatcc tatagtactt acaactaata taggtttttt
     3481 taactatttg tttggtgtat caagagaaga atgttttcca ttgatacata tgataaatag
     3541 tgtaattata ttagatgaaa tacaaaatta taaaaatgag atatggaaag aaattatttt
     3601 gtttttagaa aaatatgcag atatattaaa tataaaattt attataatgt ctgcaacttt
     3661 acctagatta aataaattag gatgtaatga tgataatttt gcatatctag taaaaaacag
     3721 agaaaaattt tttaaaaatc acctttttaa agatagagta aacataagtt ttgagatgtt
     3781 aaattcagaa attaatgata ttgaagaaat atcagaaaag gttatagaag aagcagaaat
     3841 atataataag atactgatag agtttataaa gaaatcatca gcactaaaat tttataaaaa
     3901 tattaaagaa aaattgaagt ataagttaga agatgttttt ttattaacag gtgatgataa
     3961 taaattagaa agaaaaaaaa taataaataa aattaaagat atgaactctg taattttggt
     4021 tgctacacaa gttgtagagg ctggagtaga tatagatatg gatttgggat ttaaagatat
     4081 atctacaatt gattctgatg aacaattttt gggaagaata aatagatctt gtaaaaaatt
     4141 aaattcaaaa gtatactttt ttaatttaga tgatgcaagt aagatatata agaaagatgt
     4201 tagaaaagag agacatttaa ctcttaatga ggaaagtaat agaaaaatta ttttagataa
     4261 agactttgaa aagtattatg ataaaataat agccagaata gaagaaaata agcataaaca
     4321 taatgacaag aatatagagg tttttataaa agatattgtg ggaaatttga attttacaga
     4381 ggtaaaaaaa tggatggctt taataccaga tttaaaagag tatacaatct ttttaaatac
     4441 tatagttaaa gatgaatctg gaaatatgat tgtaggaagt gatgtatggt atgaatatat
     4501 atcactacta aaaaatgata atgttgagta ttctgaaaag agggtgaaaa tgtctgaaat
     4561 tatggaaaaa ctagattatt ttacgtataa agttcagaaa tttgataatt catttaatga
     4621 tttagttgga gatatttttt atattgatga tggaagtaag tattttacag agggaaagtt
     4681 tgatagaagt aaatttaatc aaaatgaatt tctataatgt atttagatta tatagagaat
     4741 atttatccca agttaattaa ttagaattag tttaaaacta ttgaaatata gatattttat
     4801 agcttatata ttttttctag gattagctgg gataaaaaat ctgtatatta gtgttttcag
     4861 tgtatttaag gggattatat ttttaagaag tactgatttt aaagtggtta aacagtaaca
     4921 tgagatgtat ttaaattttt actacataat taaatcgtag tcaataccgt acaggttaaa
     4981 cagtaacatg agatgtattt aaatctctga atagccaatc aactttgctg cattactctt
     5041 gttaaacagt aacatgagat gtatttaaat gataatagtt atatatattt tttacaatat
     5101 attattgtta aacagtaaca tgagatgtat ttaaatttac ttctcctgtt ttgaaatcta
     5161 tatattcatc atgttaaaca gtaacatgag atgtatttaa atataatatt gatacaaata
     5221 ttttgggtaa atggacttgt taaacagtaa catgagatgt atttaaattc gatatggtaa
     5281 caaatttata aaagatatag aatgggttaa acagtaacat gagatgtatt taaataaaga
     5341 aaaacgaaat tggtgatttt gaagcaatgt gttaaacagt aacatgagat gtatttaaat
     5401 tagtaactac aatgcttttc cttttgaaga tgatatgtta aacagtaaca tgagatgtat
     5461 ttaaattaat aatgcaccta ttttaacagt acctggtcta aagttaaata gtaacatgag
     5521 atgtatttaa attcaagtct aggagacaac ataaatagta cagatgggtt aaacagtaac
     5581 atgagatgta tttaaattta aaaacatctt gaggaatatc tttaacagta attgttaaac
     5641 agtaacatga gatgtattta aatgcatttt caggtgcatg ataaataggt aaattagatg
     5701 ttaaacagta acatgagatg tatttaaatt ttttgtaatt agccagatta tcaactccca
     5761 aaatagttaa acagtaacat gagatgtatt taaattaaat atcgtccttc gtagtcaaag
     5821 caacaccaga aggttaaaca gtaacatgag atgtatttaa atcgtaaaca aaatttatca
     5881 agagaagaat ttctaaggtt aaacagtaac atgagatgta tttaaattta tatttgataa
     5941 gagtatcaaa tcgacttaaa atagttaaac agtaacatga gatgtattta aattcaatct
     6001 taatacacag acatttttaa aaacaaaacg ttaaacagta acatgagatg tatttaaata
     6061 aatagacaaa tattgaatag ctctgtcttc atcaagttaa acagtaacat gagatgtatt
     6121 taaatatatt tacaaaatct ctaacatatt ttttaacttc tgttaaacag taacatgaga
     6181 tgtatttaaa ttcttttaaa gagtcctcgg gagcctcgaa aacttcagtt aaacagtaac
     6241 atgagatgta tttaaattac tcaaataaat ttctaatttg tttatctact aacgttaaac
     6301 agtaacatga gatgtattta aattagaatt tacaacaata taagcctctt taaccataag
     6361 ttaaacagta acatgagatg tatttaaata tgtttttagt agtacattta ataaaacttt
     6421 ttaaagttaa acagtaacat gagatgtatt taaatgaagg aaccgtacct tgataaatca
     6481 cgaccgtacc cgttaaacag taacatgaga tgtatttaaa ttgtatattt gatgttgtta
     6541 tttctcctgt gtataatgtt aaacagtaac atgagatgta tttaaatgaa gttccacccc
     6601 caccaccccc actactttga gaagttaaac agtaacatga gatgtattta aattaacaat
     6661 agagtaaata taataaacaa gcatacaaag ttaaacagta acatgagatg tatttaaatc
     6721 cccttttgca tggtactaga cacgcatata tggtggttaa acagtaacat gagatgtatt
     6781 taaatacgcc tatatgcgga gtaacagatt tttgcctgga tggttaaaca gtaacatgag
     6841 atgtatttaa atactgtttt gggatagact ggaattaaat ggtctgtgtt aaacagtaac
     6901 atgagatgta tttaaatttt tggaatgaag catcaacaga taataaagaa aaagttaaac
     6961 agtaacatga gatgtattta aatcaaggaa acaaaagaga agtgaaaaga aatataatgt
     7021 taaacagtaa catgagatgt atttaaataa tcttttaaat ggaaattaag taataaaaga
     7081 gagggttaaa cagtaacatg agatgtattt aaattcaatt aaataagcat taatcttagt
     7141 aaaatcaaac gttaaacagt aacatgagat gtatttaaat tttcttgtgt taattgaacc
     7201 cccattttaa gctccagtta aacagtaaca tgagatgtat ttaaatcaga atacagcttc
     7261 tatatctgga tacatttgtc ttggttaaac agtaacatga gatgtattta aatgtgaaaa
     7321 gtaatacagg tatagagtct aaacgctcgg ttaaacagta acatgagatg tatttaaatc
     7381 aatgtatcct cttttttagt tttggagcct cttttgttaa acagtaacat gagatgtatt
     7441 taaattagtt agcacatttt atttcaagcc ttaaaacatt cgttaaacag taacatgaga
     7501 tgtatttaaa ttaatttgca cacttaacct ctaatcttaa agtattagtt aaacagtaac
     7561 atgagatgta tttaaataac acaatattat ctttaataga attaaacaaa tgagttaaac
     7621 agtaacatga gatgtattta aatttttgtt ggtcttgtgc ttcttttaaa agctgattag
     7681 ttaaacagta acatgagatg tatttaaatt taaaaagttc tgttattaaa acatccaaac
     7741 caatcgttaa acagtaacat gagatgtatt taaattctgt accatctagc caaaccgttt
     7801 ttgaagttaa agttaaacag taacataaga tgtatctaaa ttactctatc ataaaatttt
     7861 aatatattaa acaaactaat atgtgatata cttatgtata aataacaaaa taaataggtg
     7921 atgttatgaa aattacagga actttgataa attactattt ccattgtaaa agacaatgct
     7981 ggttgcttgg taatagaata aatttggaag aaaatagtga agatgtaaaa ataggtagac
     8041 ttcttcatga actaaaagaa gaaaaaacaa aatataaaga aattgcaatt gaaaatataa
     8101 aaatagacaa attaacaaga gaatatttag tagaggttaa aaagtctgat gctgatatag
     8161 aagctgttaa gtggcaagtt cttttatatt taaaaaagtt aaaagaaaag ggaattgtaa
     8221 gaaaagggaa aattgaattt atagaaaaaa ataaaactaa taaaaaaata gtctttgtag
     8281 atttgagtga agtatctgaa gaacagctta tatctataga aagagaaatt gttaatttaa
     8341 taaatagtga taaagcacca tgtcctgatt taaaaaaagg atgtaaaaaa tgtgcctatt
     8401 atgaatattg ttatatataa agaggtataa gaaacatata aggaggtgtt aatattggga
     8461 aagacaaaat atattacctc aatgggtgaa ctcacaagaa aagataattc tatatgtttt
     8521 agaaaaaa
//
LOCUS       DAYAKB010000119         8481 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.120, whole genome shotgun sequence.
ACCESSION   DAYAKB010000119 DAYAKB010000000
VERSION     DAYAKB010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.120"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..355)
                     /locus_tag="ACGI3L_003443"
     CDS             complement(<1..355)
                     /locus_tag="ACGI3L_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199135.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEE"
     gene            574..807
                     /locus_tag="ACGI3L_003444"
     CDS             574..807
                     /locus_tag="ACGI3L_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9199136.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            791..1204
                     /locus_tag="ACGI3L_003445"
     CDS             791..1204
                     /locus_tag="ACGI3L_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199137.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            1223..1519
                     /locus_tag="ACGI3L_003446"
     CDS             1223..1519
                     /locus_tag="ACGI3L_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199138.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKNYLNRF"
     gene            1803..2120
                     /locus_tag="ACGI3L_003447"
     CDS             1803..2120
                     /locus_tag="ACGI3L_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199139.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            2256..2720
                     /locus_tag="ACGI3L_003448"
     CDS             2256..2720
                     /locus_tag="ACGI3L_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199140.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(3048..3209)
                     /locus_tag="ACGI3L_003449"
     CDS             complement(3048..3209)
                     /locus_tag="ACGI3L_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199141.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(3261..3656)
                     /locus_tag="ACGI3L_003450"
     CDS             complement(3261..3656)
                     /locus_tag="ACGI3L_003450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199142.1"
                     /translation="MLKELLDDAGFDNKSKLLTAKTLYKKAEIDLPIEINEEEHYFDT
                     KQIASKLKIYSKSNKPAQMAVCEIIKKIDLEDGEVKGVWEINGSWTGTVNKYTKSVID
                     KVRTWIEENNRPTKIAGEKKNYYVFYKIE"
     gene            complement(3709..4074)
                     /locus_tag="ACGI3L_003451"
     CDS             complement(3709..4074)
                     /locus_tag="ACGI3L_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HFG9199143.1"
                     /translation="MKNELMMFEGKEIEVFEFEGRILFNSKDVANCLDIKNVNENIIL
                     MNEKQVVKLRNSDISNTDIRKLNNAGENFLTESGVYKLIFKSRKEEAERFQDWISDEV
                     LPSIRQTGAYITNNVIPKS"
     gene            complement(4194..4382)
                     /gene="srl"
                     /locus_tag="ACGI3L_003452"
     CDS             complement(4194..4382)
                     /gene="srl"
                     /locus_tag="ACGI3L_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor Srl"
                     /protein_id="HFG9199144.1"
                     /translation="MNKIATKSRAEYMKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     repeat_region   4537..5352
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4602..4630
                     /rpt_unit_seq="atttacattccatatagttaatctaaaac"
     gene            complement(5619..6467)
                     /locus_tag="ACGI3L_003453"
     CDS             complement(5619..6467)
                     /locus_tag="ACGI3L_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9199145.1"
                     /translation="MWILVPIITIVLLIIAVSSMQYILVMIAFLLIIYSFIEKKIVMG
                     LVSVLFFTYSIYLCATWEDKSLIADNKVETVRAQRETVEREKEMERRRIQEEVDKERY
                     IEKHGMEISENDLKVKLEALVPQEYKGKKYELKVGKFKRYSMYFDLTVQNEKFSNSEE
                     CKKFVKEIANDLKKIKISKAYFKFHSKDDGGIYNSVYIDYFRNIQNNVDNVENLEFNE
                     FELKTEEEEKREQEKIEQEKNSYNNYIQNRVVDPLDRIKKLKELLDSGAITQEEYNKK
                     KKELLE"
     gene            complement(6736..6888)
                     /locus_tag="ACGI3L_003454"
     CDS             complement(6736..6888)
                     /locus_tag="ACGI3L_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199146.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            complement(7162..7485)
                     /locus_tag="ACGI3L_003455"
     CDS             complement(7162..7485)
                     /locus_tag="ACGI3L_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HFG9199147.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            complement(7521..7775)
                     /locus_tag="ACGI3L_003456"
     CDS             complement(7521..7775)
                     /locus_tag="ACGI3L_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199148.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            complement(8207..>8481)
                     /locus_tag="ACGI3L_003457"
     CDS             complement(8207..>8481)
                     /locus_tag="ACGI3L_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9199149.1"
                     /translation="SRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCG
                     YKNEEVKDLNIREWIYPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         2828 a         1364 c          896 g         3393 t
ORIGIN      
        1 attcttcgag ttcacttaat ttatcttcat ccacttcgtc gtcttcacca tgtaacgctg
       61 acattaaact tgaaattgaa tttttatgta tgttcttcaa aaattccttt gtttcaaacc
      121 ttagatattt tttctctttt actagtatat tataatgtgt aagtttgcct attttctctg
      181 tacttaaaaa ctctcttcgc tctaatcttt tcaaaactgt aaatgtagtt gattcattcc
      241 actcatattt ttcttccatt gcagcaacta attccctaga agttaatacc ttgttagctt
      301 cacaaatata tctcataact tttaattccg cttctggtaa tttactaatt ttcataattc
      361 gcgccccttt gccgatttat gtatatgtta aattctatat caataaagtt ttacaaacaa
      421 gagaattaag gtaaataatt ccatccaatt tttaccatat tattctttta ggttttataa
      481 tacttatcta atgagattga cattttactc attttaggat attatgaagt taacttcaca
      541 tgaagttagc ttcatataga aagaggttat ggaatgaaaa caaaagtacg agaatttcga
      601 acaaatatgg gtctaacaca gcaacaactc gctgatttag tccatgtatc aaacagaaca
      661 attatttcta ttgaaaaaga gcaatatagc ccttctctta tgcttgccta tcgtatggca
      721 caagtgtttg gtacaacgat tgaagaacta tgttgtttaa aagaaaataa agaaatggag
      781 gataaaaaac atgaaagtaa agagtaaacg aagttttata gtgggtatta tagtttgtgt
      841 gttatgttgt gctagtttag ttatttattg cattttaaaa gataaaagat tcctaatttc
      901 atcatttctt ttaattgtaa tagcaatctt taatttttgt aatgcttttt caagaaaagg
      961 cattgttgaa gaattacacg atagtacaga tgaaagagac ttgtacttaa caatgaaaac
     1021 aagtcatatc ttagttaaaa ttatgaatta tacattattt acttttacat ttcttttcat
     1081 catagcttat agtgcatgga aaaatcaatc acttctagtt atagctataa cactatgtgt
     1141 cattgagatt tttttatttg ttgcatattt acttatcaat atatttttag agaaaaaaga
     1201 gtaaatacaa ggggtgatat aaatgtattt taaaacttat atactaaaaa gagaagtaaa
     1261 taacaaacaa ctagagataa ctcgaagttt tgacttagat aatctaattt gtactgcaac
     1321 agagattttg aaagataatg agattgattt gataattact gatgaagtaa ataatgttgt
     1381 ttggagaaat gaaaaaagca ctcccccagc aagagaatgc ttagttatag ctatagaagt
     1441 gtattggtgg tacacttcta tttttttatt atatcatata aattatgtta tcaaaaagaa
     1501 ctatttaaat cgattttaag gtgtgttgaa taaggttctt gatagtttat atattgatga
     1561 atttcaaaaa aaataagcac tctttattat aaggagtgct ttggtgtatg ttaatcttct
     1621 atctaataca attataacat gtcttatgtt ttagtatgat aattttcgtt cgctttatta
     1681 ttacaatttt tactatagtt ttatctatcc tgttaatatt tgtaatattt tagatactct
     1741 ttgtacttgt gttactgata tactttgatt aagaaaagca aatttaatag gaggtatctg
     1801 ctatggattt tggaaatatc aatcttatac ttattggaat aatagttata ataggaacta
     1861 caataatata tttaattaaa cctaaaactg ctttttgtag taaaaaatat tttaataaat
     1921 tagaatcaat atatggaaat atagataaga aaaaaactgt taaactagaa gtactttatc
     1981 gctatgtaac aggtcttgag tatatagcaa taggcttatt tacaagaaga ttagatatta
     2041 caataatagc aataatatta gtagccatta taacaacagc attatattat ctaattagaa
     2101 agaaatatat aactatataa aaaataatat cttataaata ataagcctat cattatactc
     2161 tatttttagc taaaatcgtt cgacaaattg ctgatataag ttcttaaata tgctataaat
     2221 taaagtatat tatataacat tgtaggaggg attttatgga ttttggggaa gttaaatcag
     2281 agttaagtga caaagacctt aaagataatg aagaagcttt aaacaagtat aaaaaatatt
     2341 atttaaaagt ttataagtat tatagtgaaa tggattccat aaaaagtatt caagatatag
     2401 aaatagagca atctaggctt aaaggacagt tacaaaaaaa tagtaacccc atttttgctt
     2461 tgtatatatc tattatggct gttgtatttt ctacaacaat taacttaaca tttgatttat
     2521 cagatatcac taattatttt attagaatga ttatgacact tttatttatt gtacttctta
     2581 tttttttagt taacaagggc attcttccaa tagctatacc ttatagaaat aatatacaat
     2641 tttatactac tgcattagat gtattagaag atatgaaaaa taaaatactt agagagagaa
     2701 agtataaaaa aagaaggtaa caaccaactc tagttgctac cttctaatct atttaactaa
     2761 gttttctact tcactaaatg ctttctcatt tccatttcca ccaatttgag ttatatttct
     2821 aaattctctt ttatttatta aacttttttg agtatcactt attccatctc caactaatcg
     2881 tactagagat tctgtcttac ctgcaggtac tcctactgat aaagcgtcaa ctaaatcatc
     2941 ttctctattt tctccatttt ttggttaata taattctcta tctccattat accattttat
     3001 accaaacaag cacttgaaac agtagaatat ccaagtgctt tatatgtcta tttattattt
     3061 ttctctaatt ttttctcaga aagtttatat actatacttt ctaacttatt atatatatct
     3121 atatctgttt ctcttatttt caaaagttta attctatatt cttcttttct cttttcaata
     3181 tacatattat caagtaaatt ctcacacatt gtattaatcc ccccaaaact aaactaaatt
     3241 atttaataca actgataaat ttactcaatt ttgtaaaata cataataatt cttcttctca
     3301 cctgcaatct tggtaggtct attattttcc tctatccaag ttctcacctt atctattaca
     3361 ctctttgtat atttatttac agtaccagtc caagaaccat taatttccca aacaccttta
     3421 acttcaccat cttctaaatc aatcttttta ataatctcac aaacagccat ctgagctggt
     3481 ttattactct tagaatatat tttcagttta gatgctattt gttttgtatc aaaataatgt
     3541 tcttcttcgt ttatctctat tggtaaatca atttctgctt tcttatataa tgttttagct
     3601 gttaatagtt ttgatttatt gtcaaagcct gcatcatcta gcaattcttt taacatagat
     3661 gtactgttat aagcaactgt aatttttcaa tctcacttgc tttttctctc aacttttcgg
     3721 gattacatta ttagttatgt atgcaccagt ttgtcttatg cttggtaaaa cttcatcgct
     3781 tatccagtct tggaatctct cagcttcttc ttttcttgat ttaaagatta atttatacac
     3841 tccactttca gtaagaaaat tttctccagc attattaagt tttcggatgt cagtattact
     3901 gatatccgaa tttcttaact ttacaacttg cttttcattc ataagtatta tattctcatt
     3961 aacatttttt atgtctaaac aatttgctac atcttttgag ttgaataaaa ttcttccttc
     4021 aaattcaaat acttcaatct cttttccttc aaacatcatt aattcatttt tcataatatt
     4081 acactcctta ataattgatt tttttaagga atgacatata ttataattga tatacgatag
     4141 tatacatcat aggggttact caaactttgg tcggtgggag tgacccttat tttttattcc
     4201 ttttgttcca gttcctcgtc gattttttct tctagccatt ctttcttggt tagattcttt
     4261 tcctctaata cttcatcaaa tttatctaac ttttctttgt ctaaaagtac actaaaacct
     4321 cttttatctt ttcgacaatt tttcatatac tctgccctac ttttagttgc tattttattc
     4381 acctcttttc tgtaactcgt tacattaata ataatattgt aacgagttac agaaaagagg
     4441 tttttactaa ttttttctaa tgattttacc caaccgacca attttgagca gaataaaagc
     4501 acctacatat ttgtaagtgc tttctttgtt tatttaattt tgaatccaca tagttaatct
     4561 aaaacacaat tattaattgt tttattagtg aaatcacagc aatttacatt ccatatagtt
     4621 aatctaaaac atataaaatg ggattagtaa aaaacacaac aggaacattt acattccata
     4681 tagttaatct aaaactttct tcgtctttag atgattgttt tattgttcat catttacatt
     4741 ccatatagtt aatctaaaac gctttgctta taaagtagta gacgaagcta aaaagctatt
     4801 tacattccat atagttaatc taaaactatg aaagaactag gattaagtgc ttttgattct
     4861 aaatttacat tccatatagt taatctaaaa cgtatgcttg tttattatat ttattcaata
     4921 gtcatgagaa tttacattcc atatagttaa tctaaaaccc acgcatttta gttcaaattc
     4981 gaagtttttg gctgatttac attccatata gttaatctaa aacctatcct ttcattcatt
     5041 taaaatttat tcctttcaaa tatttacatt ccatatagtt aatctaaaac acgacgttga
     5101 gattgcggag cttctcaacc ttgtacgcat ttacattcca tatagttaat ctaaaacaaa
     5161 gaagtcatca aagcaatgca aattaaatgt aatatttaca ttccatatag ttaatctaaa
     5221 actataatta gtattaaaaa aattcttaat tctatacaat ttacattcca tatagttaat
     5281 ctaaaactgt cataaaaatc atcaaaattt ttacccatgt aatatttaca ttccatatag
     5341 ttaatctaaa accccaaaat aaacttagca tttccaatac ctacatatat acaatactct
     5401 taaaattgca gtgagcgggc aatagtgcaa ttgataacac ttatcacgca ccctcaacat
     5461 cttagatttc aagtattaag ccctactttg taacaaatat cgcacactgc aaaacttcta
     5521 tatttttatt atatcataaa atctaaacta taaaattaaa atggaatact ttgtaaattt
     5581 aaaagcacct acatacttgt aagtgcttac tatattatct attctaataa ttcttttttc
     5641 tttttattat attcttcctg tgtaattgct cctgaatcta gcaactcttt tagtttcttt
     5701 attctatcta gtgggtcaac cactctgttt tgaatgtagt tattataact gtttttttct
     5761 tgttctattt tctcttgttc tcgcttctct tcttcttcgg ttttaagttc aaactcattg
     5821 aattctaaat tttcaacatt atctacatta ttttgtatgt ttctaaaata atcaatataa
     5881 acagaattat atataccgcc gtcatctttt gaatgaaact taaagtacgc cttgcttatt
     5941 ttaatttttt taagatcatt agcaatttct tttacaaatt ttttacattc ttcagaatta
     6001 ctaaattttt cattttgtac agttaaatca aaatacatac tatatctttt aaattttcct
     6061 acttttaatt catatttctt ccccttatat tcttgaggta ctaaagcctc tagcttaact
     6121 tttaaatcat tttctgatat ttccattcca tgtttttcaa tatatctttc tttgtctact
     6181 tcttcttgta ttcttcttct ttccatttct ttttctcttt ctacagtttc tctttgtgcc
     6241 ctaacagtct caactttatt atctgctatc aaggatttat cttcccaagt tgcacaaaga
     6301 taaattgaat aagtgaaaaa aagaactgac acaagaccca taactatttt cttttctata
     6361 aaagaatata taatcaacaa aaaagctatc ataactaaaa tatattgcat agaagaaaca
     6421 gctattataa gtaatactat tgttattatt ggtactaata tccacattat aaaattcccc
     6481 cacaaattac tcatctcact caatattata gcataatttg gcaaaacaaa agcacctacc
     6541 atttaagtaa gtactttctt atttacaatt aaatttattc atctagttag attcatcatc
     6601 attgtgtata aaaaatttca tatttttatt gactataaaa aatattatat gcaatatttt
     6661 ttctaatttg tggtataata aaaacaagaa gaactacaat ctatttgcgg tagagtgaag
     6721 ttctataact gaaagttatt ttttacgatg atatttaaaa tttatatcaa tctttaagtc
     6781 actctttgcg gtagagtggc tttttacttt tttgattaac ttgctaatca aataaactat
     6841 gtaactagct gttacactag ctaacacatt aaataaaaaa ttatccatgt atattcacct
     6901 cccttcttat cgttgggagg ataatttttt aatacatgaa ctccactcta taaattgtag
     6961 attacatctt cttgctacaa ttattataac atataattct tacatatttt tcctatatct
     7021 tactttttat tttattttct attttttcaa taaaaagcac ctacatattt gtaagtgctt
     7081 tctatgttta tttagtttta ttgattactt aataggttag tacaaattcc ataccaacct
     7141 aagaatatct acataaaata attaaataat ataatcaata agtatttttt ttactctttt
     7201 aatcaaatta ttacctgttc cccaatcaat ctgaaatagt ccaattgcac taccagttga
     7261 ggtaatttta acaagtgttt ttcctgtagt attttcacaa atcactacca aacctgcatc
     7321 actattgctt cttgcataat atttttcaaa gattgtaact attatagact tattattttc
     7381 taggttataa atatcaacag aaactaaatc tgcttccaaa tttttttcta ccattttctg
     7441 tgcttctagt ggtgtcatct ttacactaaa tacatctctt gccatatcat tcatcacatc
     7501 ctaaataaaa atatactttt ttagtatttt ctgacacttt tatcaaacag tattcctatt
     7561 cctcctagta aaaccagtat agaaccaaaa tttctatatt gtgaaataga ttgttctaaa
     7621 tatatgttgt attgttcggt agctattgac ccaccatttt gttttataat acaatccata
     7681 ttaaattgac ctagacctat acagcaaaat aacactatta ttccaattac aaaagcaaat
     7741 atacatattg taagtttaat atctttattt tccacccctc ataatttaga tttatttgtt
     7801 gttttttact tggtgatata ttatctacat tatactatac aacatatata tccatctatt
     7861 tccaaatttg taacattttc atatattagc aatgtaacta ttttaacttt aaattctacc
     7921 ttcttctacc tctctttttc tctctttcag cttctttcat tgtttcttct tcatcttcaa
     7981 ttttaataag tattgagtcg gctgctaatg ctctctcatt aacttctaaa ttcatatatt
     8041 cactaggttt ccactttagc ttttgaatac aataatgagt aatactagcc tgaacctccc
     8101 atgactaaag tcacaggttt cctgcttcac agaattttgc atactaacat atgtcttact
     8161 aattctccac aggctatccc cgtagttcct acggttctta catacgttat ttattttgaa
     8221 ttgttattag tcttaatcct tcttttaata tatttatact tgcatttata tctctatcgt
     8281 gagtttcatt acaactagga taaatccatt ctcttatatt taagtccttc acttcctcgt
     8341 ttttataccc acatttattg catatttgtg aacttgcaaa gaatttaccc acctttacaa
     8401 tttgtctacc atgccaatta gccttgtatt ctaattgacg aataaactct gaccatgaca
     8461 catcagaaat tgagcgagat a
//
LOCUS       DAYAKB010000120         8418 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.121, whole genome shotgun sequence.
ACCESSION   DAYAKB010000120 DAYAKB010000000
VERSION     DAYAKB010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8418
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.121"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            493..1185
                     /locus_tag="ACGI3L_003458"
     CDS             493..1185
                     /locus_tag="ACGI3L_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199150.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            1381..3441
                     /locus_tag="ACGI3L_003459"
     CDS             1381..3441
                     /locus_tag="ACGI3L_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HFG9199151.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(3646..3969)
                     /locus_tag="ACGI3L_003460"
     CDS             complement(3646..3969)
                     /locus_tag="ACGI3L_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFG9199152.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(3962..4663)
                     /locus_tag="ACGI3L_003461"
     CDS             complement(3962..4663)
                     /locus_tag="ACGI3L_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFG9199153.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(4941..6326)
                     /locus_tag="ACGI3L_003462"
     CDS             complement(4941..6326)
                     /locus_tag="ACGI3L_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9199154.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(6434..7672)
                     /locus_tag="ACGI3L_003463"
     CDS             complement(6434..7672)
                     /locus_tag="ACGI3L_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9199155.1"
                     /translation="MELFIEVIKFNIYISPLILFFILFTKKISKYTFKFNYFICLLIV
                     VRMMFISKINLNILNINNTTINIYKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYY
                     LRTNFKFYNYIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTR
                     CKIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIYWFNPILYLLKKYFH
                     ELCELSCDEIVIDKCTTSEIKEYAYIILDTIKYQKSLKYSSFVSQFLNKKNIILKKRL
                     DSMFNQDKKKINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGT
                     HIIDSNGNSIEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFK
                     KTIPLYDKEGIKIIGRFEIN"
     gene            complement(7685..8062)
                     /locus_tag="ACGI3L_003464"
     CDS             complement(7685..8062)
                     /locus_tag="ACGI3L_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199156.1"
                     /translation="MIILKKIPKSELLVMNFIWDKDIDKIPAREVANYMEISHGWTKG
                     TTGKVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISS
                     LGCGNEISDDDIKELEQWLKKRK"
BASE COUNT         3224 a          961 c         1154 g         3079 t
ORIGIN      
        1 ttatataaat tttaatagaa tatgtacagt atatagtaga tagaatgtat aaaaatagaa
       61 tttaaataag tagctattat tgcagtgaaa tgaatgtttc taagtatatt tgggtggaag
      121 aatggtggaa gaaaattagt gaaatgtaat tcttccacca ttcttccacc tagaaaatag
      181 aaactgttta ataagaatta atatacatta attcagctga atgcaatcaa aatacttaaa
      241 tgaaagtaat ctgaaaacaa cataattcaa atcaatttat tcaaataaac ctcaatttat
      301 cttaaatctt aagaaatatt taagaattag gataatattt tcttaagatt tatattttat
      361 tatatagtta taagggaaag ttacaaaaat gtaagccaaa gtaatataac aatttagtca
      421 ttgttgagaa agggagtgaa agatattgta taatatagat aagtattatt atacaataga
      481 ggaagtgaaa atatgtacaa tatattagta gtagacgatg ataaagaaat tgttgattcg
      541 atagaaatat atcttaaatc agaaggattt aaaatatata aagcatatga tggaatgaaa
      601 gctttggaaa taataacaga gaatgacatt catctaatac taatggatat aatgatgcct
      661 aaattagatg gaatcaaagc aactgtaaaa atacgagaag aaagaaatat tccaataatt
      721 ttaatttcag caaaaagtga agatacagat aaaataatag gattaaatat tggagctgat
      781 gattatataa caaagccatt taatctatta gagcttatag ctagggttaa atcaaactta
      841 agacgatatg taactttagg taattatgaa gatacatgta aagaaattct aaaaagtgga
      901 gctttggagt taaatacact aacaaaagaa gttaaaattg atggtgaaaa cataaaaatg
      961 actccaattg agtataaaat aattgaactt cttttagaaa ataaaggacg agttttctca
     1021 atagatgaga tatacgaaaa agtatggaat gaggaaagtt ttaattcaga aaatacagta
     1081 gcagtacata tcagacgaat aagagaaaag attgaaataa atccaaaaga accaagattt
     1141 ttaaaggtgg tgtggggagt tggttataag attgaaaaat tttagtggaa aaattataaa
     1201 agaaaagagt ttaatattta attgcatttt gattttagtc atttttacat ttacacaaat
     1261 gttaggaatt ttaatatgtt ttaatttttt ctctgagagt ttaatttact ctatggggat
     1321 tatgcttttc ttaaacttta ttttatataa aatactgaca atgtagatga ggtgggcaac
     1381 ttggagaaat atagagtatt aaagttagtt tcattaatca taatatctat ctcatttcca
     1441 ttaactatat tgttggtgac aataggactt gctgagccta aatacaatat acaaaaaact
     1501 tctacaaaga gtgggatttt tgatatatct gatgattttt atgatagtaa tatatttgac
     1561 gaaggaacaa tggcaagtct attacccaag tttaagctat ctgtaggtgg taaattaact
     1621 agtaaagaaa aaggtaaatt ccaacaagaa ggtaaaagta tagatttaag tagtagtgat
     1681 tctgagtatg ataaaatcat gattaatgaa caagcttctg aagaatattt aagttatcta
     1741 aaaaatataa aagtgtatgt tattaataca tacacaggag tattttatac aaatacgtca
     1801 tatgctagtt tatatgattt taaacaaaaa actaagagct attgtaatgt agagataata
     1861 aataagatag gaaagagctc atatattaaa acaataaatg gagaaaaatt tgaactgaat
     1921 aatctgagtc tggaactaaa tgaagtagat gaaggttttg aggcatatgt atcttttcca
     1981 gaagagccaa ctatagaaga tggaatagta tacactaatt ttcaaatatt taaacaagct
     2041 acagaaaaag taagattatt ttttgtagct agtttaagtt tagcaattat atgtttatta
     2101 tctataattt tatatatcaa aataaaaggt gaagttttaa aaagaaataa tgtattttta
     2161 ctaatataca gtaagatacc tatggaattt aatgtaatat tagtatctat ttcaattgca
     2221 attttaacta tatatgctct tgctgtatct tatcatattg atgtaattgc attagtttct
     2281 ttatctttac tgatagtatc aaataatata ttttttataa atgtgcaatt gagctattta
     2341 gaaaataaaa tgtgtatatt taagacaagt attatagtaa gagtgatttt atggttaata
     2401 aaaactgtaa gggaggtcag taacgctata aagaaagtat ctttagcaag gaaagttatt
     2461 gttatagtga taatatcttt agctttaatc atggcaatta gcactcgaag tataggtatg
     2521 ggattactgt tttctatatg tattttttta ggatttacaa tatatataac taaaagactt
     2581 tcatatctta gttacgtaat agaaggtaca gaaagaataa aaaagggaga attagattat
     2641 aagataaaaa ttactgggaa tgataatttt acgtctttag ctgaaaatat aaataatatt
     2701 ggagaaggtc ttgatagagc tatagaagag caagtaaaaa gtgaaagaat gaagtctgac
     2761 cttataacaa atgtatctca tgatttgaaa actccactta cttctataat aaattatgta
     2821 gatttaatta aaaaagaaga atcaatacaa ccagagtata taaatgatta tataaatgta
     2881 cttgagtcaa agtcaaaaag actaaaatta ttgatagaag atttatttga agcgagtaga
     2941 gtaagtagtg gcaatataga attacaaatt agcaagattg atttagtgca actattaaga
     3001 caaagtatag gtgaacttga agaaaaatta tctaaaaata atttatattt aaaattaaat
     3061 gttccaaatg ataaggtgta tatatgggca gatggaagaa gaatgtatag agtatttgaa
     3121 aatcttttat ctaatatagc aaaatattcc ttagaagaaa ctagagtcta tattgatgta
     3181 tatgactatg gtgaaaatgt aaaggtaact atgaaaaata tatcttctta tgaattaaat
     3241 tttgacccaa gtgagattat ggaaagattt aaaagagctg atgaatcaag gaatactgaa
     3301 ggaagtggat tagggcttgc tattgcaaga gatttagtag ctttacaagg tggaaaattt
     3361 tatatagaaa tagatggaga tttatttaaa gcaaatttag agtttcaaaa atatgaagaa
     3421 gaaataacaa atatggaatg agatagtatt taagtatata tattttttta ctgtcgaaag
     3481 cttttattat aatatattag aatatttaca gtagagaatg aagagtaaaa acagagtaac
     3541 tttaagtcac tctgtttttt atttaaaatc aataatataa caacttaaat taaaattgta
     3601 cacatagttt taaaataact tatacaataa aacattatcc aaatatcaca agataattcc
     3661 aaataaatat atagatatca ctcctgtaat aatagaaata ccaatagatt taaacttata
     3721 tgcaacaaga agtacaatca taaaagatat aattttaggg ttagctatag ataaatatag
     3781 actatctcca ttaaaaaata catctttagc agttaaggaa gtaagtattg ctacaggtat
     3841 aaatttcatg atttttttca aaaaatcagg catctctttt tttgaaaaaa ttaacatagg
     3901 aagcactctt ggtagatatg taacaatgta cattccaatt ataataaaaa atatataatt
     3961 attattcata agattcctcc tttttacagt aagattcttc tataaagaaa ccaattaaag
     4021 atgctaaaat tgatgcaact attattacta aattgctttt gaataatgca tataaaataa
     4081 cagaaataat gattgatgat ataaatacta caatataaat cttatttttt atttgagaaa
     4141 ctattaaagc tataaacata gaagtcaata tgaagccaga aatagaactg tctatagata
     4201 tactttctcc taaaaatgct ccaataaaat tagctaaaac tgatgaaatt aagcagaaga
     4261 aattaagata aatagcattt ctatcagacc aatttccagc agtaaatttt tcataattaa
     4321 ctgcaaaagt ttcatctgtt atagtatgac aaaatggcaa tataaatttt ggacttttat
     4381 tttttatgta catgttcaaa ttagaactca ttagaaaatg tcttaagtta actataaatg
     4441 tagtcaaaac aatagatgtt acacttgcac cagtagaaat cattgaagct gcaatgaatt
     4501 gagaacttcc tccaaatact aaagttacca ttagtgctat ttgaaaaggt gaaagaccag
     4561 atttttgtaa tagtattcct cctactatac ctataggtat ataacctaag aatataggaa
     4621 ttgaagcaat aaagctttct tttaattgtt gagttctttc cacaataaat cactcctttt
     4681 gtattaaatg tattaaagta ttcgtaaaac agaaaaatag attaattgta taattgcaat
     4741 tataattaaa aataaatttg gattaatata taaaatacta tacaacaaat agataatctt
     4801 aaacggttat taaattttat ctatttgtta ttatgatgta ataatacata ttaatctcta
     4861 taagttaatt actatctggt gtaattttat tttaacaaca aaaaaaaata cacacaatta
     4921 aaatattgtg tgcaatacaa ttattttttc tcttctaata gtctttttaa tacgctcaaa
     4981 ccagctttaa gttcttctgt actttctgta gcacatacag ctattcttat tgcagaaatt
     5041 ggtttttctt ttccaacagc aaaacgttca gaagcataga cctgtacacc ttctttaagt
     5101 gcttgtatct caaatttttc tgccattatt ccatcaggta gaatcaacca tctaaatata
     5161 cattcttcat ttcccaaaag attatatcca gataaatatt gattaataat cttgtttctt
     5221 cttcttgcag atttacggcg tgcattaatt aatttatcgg cttcacctga tgtaatcatg
     5281 cgataagcaa tttctgttaa aaaataagat tgagatagat taatgttgta taatgcgctt
     5341 gataatgcct ctcgatactg tttaggtgta gagatatatg ctagccgtaa actaggtgca
     5401 ataatttttg ataaactcgt aatataaatt gtttgattgg gcagatagga agccactgga
     5461 tttaaatgtg tttcattaag taaactatga atagcatcct caataacaat taaattgtat
     5521 ttagatgcaa tatttgcaat catttttcgt ccattttgtg acattatatg tgtagttgga
     5581 ttttgataat ctggtattat gtatagacct ttaatatttt catttttaca agcatataat
     5641 agtccttctt cactaatctc attatcttct tgtttaattg gaattagttg aatcccaagc
     5701 attttagctg ctgtctttat tccaggataa gttaatgggt ctacacctat tctatctcca
     5761 tgttgaaaca aaccagctaa aatagcaaca attgcatttt gtccaccact tgcaggaagt
     5821 aagctatctg atgtagtttc aagcccagct ttataaatta atttggcaat agcttctttt
     5881 tgccatttag caccatctct ttgtccatat tggaatatgg ttttaaaatc tatttcctta
     5941 attatgtgtt taaacaaagt attcatttct tctagtgtga aatctggatt cattgtgccc
     6001 atttcaataa atgtaatttt attattactg gacatcaaga atagatttga acgtgtatca
     6061 taagatacaa aagttccact tcctgtaact ccacttatta gacctttttt ttcacaaatt
     6121 ttaaaagctc tagagatagt actcacatta acatctaaga aatctgccaa ttcacgttgg
     6181 ggtggtaatt tagtacctgg taataaaaat ccattgttga tatcttgttc tagttgttct
     6241 gcaagcgcct tatataatat ttgccctttt gaaggtctct ttggtttcca gttcatagga
     6301 taattttcaa aagaattaat tggcataagt tttcacctca cattattaat ttgatttttt
     6361 ctttatctaa aacaataaat tctaaagata caaataaaaa ctgataggaa ataattctat
     6421 cagtttttgt cttttaattg atttcaaatc ttcctataat ttttatacct tctttatcat
     6481 aaagagggat tgttttttta aatatattaa aatttctttt tcttgtatat aaaacagctt
     6541 cttctggtgt ctttggttga ttatcacaat cgtacaaatc tctttttttt acgtagccga
     6601 cttttttacc tctacctatt gtttgtataa gttctggttc aatggaattt ccatttgagt
     6661 ctattatatg tgtaccatag gtttctccat ttttattata attaatctta ccaatagtat
     6721 attctacatc ttcattttgt ttaaaattgg agttgataga aaatattgac cctattatta
     6781 taaaggttaa taaaaactta agacctaaat taattttctt tttatcttga ttaaacatag
     6841 aatctaacct cttttttaaa ataatatttt ttttatttag aaactgagat acgaatgatg
     6901 aatacttcaa agatttttga tactttattg tatctaatat tatatatgca tactctttaa
     6961 tttcactcgt ggtacacttg tcaatcacaa tttcatcaca agataattca cataattcat
     7021 gaaaatattt ttttaataag tataaaattg gattgaacca atatatgata caaattatac
     7081 taattagaag cttaaataag ttatcttttc ttttataatg aattaattca tgtttaaaga
     7141 tgaatcttaa ctctttatta ttgtactttt tttctggaat tattatttta cagcgtgtta
     7201 aacctataat ggcaggagaa taaatacctt taaccttata tatctgaagt tttttattta
     7261 tacttagttc ttttgcttgt tcatctaaga tactagtaat atctatttct aaaatttctt
     7321 ttttaaaatt ttctatgtaa ttataaaatt taaaatttgt tcttaaatag taaaaagaga
     7381 ttgctataat tcctaatatc cagatgtaca taaatatatc taaagtaatg ccctggtcat
     7441 atggtatata attatcgata ttatgcttat agatattaat agtagtatta ttgatattta
     7501 atatatttaa atttatttta gatataaaca tcattctgac tactattaaa agacatataa
     7561 aataattaaa cttaaaagta tatttgctta tctttttagt aaataaaatg aaaaaaagaa
     7621 ttagtggact tatgtaaata ttaaatttaa taacttctat aaataattcc ataaaatacg
     7681 tctcctattt tctttttttt agccattgtt caagttcttt tatgtcatca tctgatattt
     7741 catttccaca acctaatgat gatataaagc tatgaataga atttttatgt ataagctcta
     7801 aaaaatcctt tgtttcaaat tttagatatt cctcatgttt aactttaata gtgtataaag
     7861 tatttctacc atctttttca aattctaaaa aacctttatc acttaatcta gaaagtactt
     7921 taccagtagt accttttgtc catccatgag aaatttccat ataattagct acttctctgg
     7981 ctggtatttt atctatgtct ttatcccata tgaaattcat aactaacaac tcggattttg
     8041 gtattttttt caatataatc actcaccttt aacttgatta tattagacaa atgtctaata
     8101 gtcaatataa tatatcatca tgtataaata atctttatat tattttatgc ttgagaacta
     8161 agtagtatag atttatagat aaaaaagata ttgagagttt tatggaagag gggaatatat
     8221 tttctattag agataagaat atgacatata ttttttattg atttttacaa aaatactata
     8281 tagtgaataa attaatatct tttctaaatt agaagaggag aatcttatta gataaagatt
     8341 atcctcttta ttgaaagttt aagggatatt agagattatt aatttttctc tcttttttta
     8401 actaaaagca ataataca
//
LOCUS       DAYAKB010000121         8351 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.122, whole genome shotgun sequence.
ACCESSION   DAYAKB010000121 DAYAKB010000000
VERSION     DAYAKB010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.122"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            42..1865
                     /gene="typA"
                     /locus_tag="ACGI3L_003465"
     CDS             42..1865
                     /gene="typA"
                     /locus_tag="ACGI3L_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFG9199157.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(1955..2863)
                     /gene="trxB"
                     /locus_tag="ACGI3L_003466"
     CDS             complement(1955..2863)
                     /gene="trxB"
                     /locus_tag="ACGI3L_003466"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFG9199158.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCITSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    3665..3896
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4004..5485
                     /gene="thrC"
                     /locus_tag="ACGI3L_003467"
     CDS             4004..5485
                     /gene="thrC"
                     /locus_tag="ACGI3L_003467"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HFG9199159.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            5495..6388
                     /gene="thrB"
                     /locus_tag="ACGI3L_003468"
     CDS             5495..6388
                     /gene="thrB"
                     /locus_tag="ACGI3L_003468"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HFG9199160.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            6518..7573
                     /locus_tag="ACGI3L_003469"
     CDS             6518..7573
                     /locus_tag="ACGI3L_003469"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HFG9199161.1"
                     /translation="MKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVISG
                     VQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEAVK
                     AGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIVVE
                     GPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSSSD
                     VKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAIRN
                     KFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAYKI
                     DKLSTVEDVINELISEL"
     gene            complement(7728..8240)
                     /locus_tag="ACGI3L_003470"
     CDS             complement(7728..8240)
                     /locus_tag="ACGI3L_003470"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFG9199162.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
BASE COUNT         3027 a         1147 c         1259 g         2918 t
ORIGIN      
        1 ctataattaa taagttattt taatcgaagg gagcaacaaa aatgtcacaa aaacataaaa
       61 ttataaatat cgcagttata gcccacgttg acgctggaaa atcaacattg gttgatgctt
      121 tcctttctca aagcggtgtt tttagaaaga acgaagtagt taaagactgc gttatggaca
      181 gtaacgacct tgaaaaagaa agaggcataa ctatatattc aaaaaactgt gcaataaact
      241 atgaagatta caaaataaac atagttgata ctccaggaca cagtgacttt tcttctgaag
      301 ttgaacgtgt tatgaaaact gttgacacag ttattctatt agttgatgct agtgaaggcc
      361 caatgcctca aactagattc gttttacaaa aatctttaga gttcggttta aaaccaatat
      421 tatttataaa caagattgat aaaaaagacc agagagcgga agaagtagtt aatgaagttt
      481 tcgatttatt tgtagactta aatgcaacag atgagcaatg cgaatttcct ataatatatg
      541 gtattgctaa acaaggtatt gctaaacttg aaatggatga tgatagtgaa gacctttctc
      601 ctctatttaa aactattgta aatcacgttg aagcttatcc taattacgat aatgaacctc
      661 tacagttcca aatatcagct cttgcatatg atgattatgt aggtagactt ggtataggta
      721 gaatttacaa aggtactctt aaaaacaata cacaagttgc tatatgtaga gaagattctg
      781 ttgtatctaa aggaaaagta tcaaaacttt ctgtgtatga aggtttaaaa caagttgaag
      841 ttgatgaagc tactagtgga gaaatagttg ttatagctgg tattcctgat atatctatag
      901 gtgaaactat atgcgattta gatagtccac tacctatgga aatgataaaa atagaagagc
      961 ctactctttc tatgaacttc ttagtaaacg actctccatt cgttggaaaa agtggaaaat
     1021 tcgttacaac tagacatttg aaagatagac ttgaaaagga acttgaagta aatgttggtc
     1081 ttaaagttga acctcttgat actactgatg gatacaaagt ttctggacgt ggagagcttc
     1141 acttatctat actacttgaa aatatgagac gtgaaggtta tgaagttggt gtttctaaac
     1201 ctgaagtttt aatgcataaa gaagatggaa aattaatgga accaatagaa agagttgttg
     1261 taaactgtcc tgaagtttac tctggtacta ttataaatga attaaacatg agaaaaggta
     1321 tgatggagtc tatgtcaata gaaggagact atgtaaaaat agagttctta gcacctactc
     1381 gtggtctttt aggatatcga agtgaattta taaacgctac tcgtggagaa ggtactttag
     1441 ttcgttcatt tgaaaaattt gaagaattta aaggagaaat accttcaaga ggaaatggtg
     1501 ttttaatagc acaaggacct ggtgttacta tggggtattc tcttaatgcc ttaagtgata
     1561 gagctgtaat gtttgtagac cctggtgtag aagtttacga aggtatgata attggtatga
     1621 attccagaaa agatgatatg gtagtcaacc cttgtaaaaa caagaaaatg agtaacgtac
     1681 gtgcttctgg ttcagatgat gctataaaat tatctcctcc tagaatattt actcttgaag
     1741 aagcactaga gtttatagaa gatgatgaat tagttgaaat tacacctgat tctataagac
     1801 ttagaaaaag attcttaaat gaacatgata gattaagata taacaaatct agacaaggta
     1861 aataaaacgt acatttacct ctaattaaca aaatagccat atagtactga aaaattattt
     1921 cagtttatat ggctattttt atttgaaatt tatattattc aacatttata taattagctg
     1981 cttgaacggc tgcaatagct ccatctgatg ctgctgttat tatttgacgt aaaaacttag
     2041 ttctactatc tcctgctaca tatacacctt ctactgatgt tatacaagac tcatctgaaa
     2101 ttatatatcc accttcatcc aaatcaagaa cattttcaaa cattttatta ttaggtttaa
     2161 gacctatagc aataaaaata ccactaacat ctatagttct tttttcttca gtctttaagt
     2221 tttttacttc tattttcgat acagtctttt ctccttctat tttttctaca ccatgactgt
     2281 aaagtatctc aatattctct cttgctttca cagatttctc caacacttct tcacctctaa
     2341 aactatctct tctgtgaatt aaatacactt ttgtacaatt attagctaaa aataaagcat
     2401 cttctagtgc agtatttcct ccacctacta tagcaacttc tttatcttta aaaaaggctc
     2461 catcacatgt tgcacagtaa gatactcctc tacctgtaaa ttcttgttcc cctgcacaac
     2521 ctaatttacg tctttcaact ccatttgcaa gaataacagc ctttgcttta tgttcacctg
     2581 aagaagtttt tacaaccttt acttttccct ctaaatttat ctcttcaacc tcatcaaact
     2641 gaatatcaac accttgagca actgcttgat tgtatatatt attagaaaat tctaccccag
     2701 aaatcttttg aactgctgga taattttcta cctcagaggt acttgcaact tgacctccat
     2761 aaatattttt ttcaaatact gtaacgctta accctgctct catagcataa attgctgaag
     2821 ttaaacctgc tggtccagca ccaattacaa tgatatctac cataacgttt acctctcttt
     2881 atattattat ttcttatata ttattctcat cattcttata ctttactatt attatccata
     2941 tatactataa acaaaacatt attttttatt aattaacttt attttacata tatataaaaa
     3001 aactgcaaat aaaaattaac ttttatttac agttctcact tatttatata attcaaaacc
     3061 ttattggtta tcatttacag tgtcttctaa tatattgctt tctgatatat atgatagaat
     3121 tgaaagtcca tacataacca aaactaatgc tgctgttata agtactattc ccatatttaa
     3181 tacctccttt tgtttacagt atactattat tatgtgaaat atttatgaat ttaatttgaa
     3241 tatatatgta atttcacact aacaatttct tcaaattaaa cattattaac tatatacttt
     3301 tgttgaacca attatgatta atagtttaaa tattagcact atttacttat atttatatga
     3361 tataccatat aattacattt ttcaaattaa agttttgtaa actttttttg taatatagtg
     3421 tagtataaaa ttgtaatatt acagatattt aatagttatc ttttaattac tttcattaaa
     3481 aacagcttca tcactatgaa aatctaggtt tttaaacttt taaaaaggtt aaaaaaatat
     3541 ttttctaata ctcaatttga ttacaatttt tttacaattt aaaaaatatt ttttccaaat
     3601 ttttatatta atacttgact ttgtctgttt tataaactag aataattaat aatattaaga
     3661 atattgaaag gcattgatta ggaagagtaa atctgaatcg attaccagag aaggaaacta
     3721 ctagctgaaa tgtttcccta attagaagga ttgaaaacta cctaggagct tctatccgaa
     3781 gttatcttaa tgattttagt aggaatagac gtttttatta cttgcgttaa agtatcaagt
     3841 ggatttttta aaatcaattt gggtggaacc gcgggaaaca gattctcgtc ccttttttag
     3901 ggatgagggt ctttttttat tacctaaatt cagtttttaa aatattctgt atctaattta
     3961 attagctaat taaaaattta aaatatatgg aggattataa aaaatgtatt attcaagtac
     4021 gagaggcacc gaagaaaaag taactgcatc acaagcaata ataaaaggaa tatcaaatga
     4081 tggtggtctt tatgttccaa gtgaatttcc caatgtaaaa aatgaactta taaatttagt
     4141 aaatttaacg tattctcaga tagcattttt tgtacttagt aaatttttat gtgattttac
     4201 tgaagatgaa attaaaaatt gtatagaaaa tgcatatgat gaaaagtttg attgtagtag
     4261 tatagctcca ttaaataaag taaatgatac ttatttctta gaactatatc acggtccaac
     4321 tttagcattt aaagatatgg cacttactat aatgcctcat cttcttaaaa catctataaa
     4381 gaaagataat ttagagaaag atgttgtgat tcttactgct acatctggag atacaggtaa
     4441 agctgcactt gagggattta aagatataga taaaataaag ataattgtat tcttcccaga
     4501 agatggtgta agcccagtac aaaaacttca aatgaaaact caaactggaa aaaatacata
     4561 tgtagttggt ataaaaggaa attttgatga tgcacaatca ggtgtaaaga agattttttc
     4621 tgataaagaa tttaatcaaa aactattgga taataattat atattatctt ctgcaaattc
     4681 aattaatata ggaagacttc ttccacaagt tgcatactat ttttattcat atatgaaatt
     4741 agttagcaat agtgatataa atttaaatga taaaataaat tttgttgtcc caactggtaa
     4801 ttttggtaat attctagctg gatattatgc taaacaaatg ggtcttccaa taaacaaatt
     4861 aatatgtgca tcaaatgata ataatgttct ttatgatttc tttaaaactg gtgtatatga
     4921 taaaaataga acattgaaat taactacttc tccttctatg gatatattaa tttcaagtaa
     4981 tttagaacga ttactgtttg aaatatcaaa tagaaatact gatattgtaa ataagctttt
     5041 atcagacctt agtgataaag gagtctacaa aataagtgat gatatggaaa aaaatttagc
     5101 ctcattctat ggagaatatt caaatgaaga agaagttaaa agcacgataa acaatgtgtt
     5161 taaaaattat aattatttga tagatactca tactgctgtt gcatacaatt gttatgaaaa
     5221 atataaaaaa gaaacttctg ataacacaaa aactgttatt gtaagtactg caagtccatt
     5281 caagttttct gaagatgttc taaagtctat agattgtgat tttaaagacc ttgatgactt
     5341 tgctataatt gatagattat caagtatttc taaaatagat attccaaaac ctattaaaaa
     5401 tcttaaaaat gcagaaatac tacataaaga tatttatgaa aaagatgaat taaaactagc
     5461 tataaaaaaa ttcttaaagg tataggtgat tattatgtta gagattatag ttcctgcaac
     5521 aagtgctaat ataggtccag gatttgattg tcttggaatt gcgttaaata tatacaataa
     5581 attttatgtt gaagaaattg aaagtggtct tgaaatagaa ggttgtgaag atgcttacaa
     5641 aaacgaaaac aacttagttt atacatctat gaagtacttt tttgatagag ttaaaccaga
     5701 aaaaatacct gctggtatca aaataaaaat ccaaagtgaa gtacctatat gtagaggtct
     5761 tggcagtagt gcctcttgta tagtagctgg agttatagct gcaaatgctc tatcaggtgc
     5821 taatttagat aaaaatcaat tactaaatat agcttcagaa atagaaggtc acccagataa
     5881 tgttgctcct gctattttag gaaatatgat tgtatctgtt actgataatg agaatataca
     5941 ttatgatatt ataaaaattc ctgaagaact taaattttgt gcaatgatac ctaattttaa
     6001 gttatcaaca gaaaaagcta gaggtgtttt accaaaggaa ataccatatt ctgatggggt
     6061 attcaatgtt agtagagttg ctttactaat atctgcctta ctaaacaaaa actttgacct
     6121 acttaaagta gcttgtcaag acaaattgca tcaagattat agaggaactc taattgagaa
     6181 ctacaatgat attgttgaaa aatctgaaca attaaatagt attggagtat ttttaagtgg
     6241 agctggacct actataatgt ctttaataaa agaaaatgat gatagttttg tggataatat
     6301 gaaaaattac ctacaaaaac taaaatctga ttgggaaata aaagagttat gttgcgattc
     6361 taatggagct gttttaaata taatataatt atcgtcttct atacaaaata taactactct
     6421 tttattataa tttgtagtat aataattagg actaggtaat aatattaagt attataatct
     6481 agttctttaa acatgtttac attgaggagg gattatcata aaagagttaa taattagaga
     6541 tttagttgca aaagttccta taattcaagg tggaatgggc gttggtatat ctaggtcatc
     6601 actagctggt gcagttgcta agcttggtgg tgttggtgta atttctggag ttcaaattgg
     6661 atatgatgag gaagattttg aaactaatac tataaatgca aatttaagag ctataaaaaa
     6721 acatatttct aaggccaaag aaatctcaaa tggtggtatt attggtatta attttatggt
     6781 agctatgaaa gaatatgaaa catacgtaaa ggaagctgtt aaagctggtg tagaccttat
     6841 aatatctgga gctggattac ctaataagct accatcatta gtaaagggaa gtaatgtaaa
     6901 aatagcaccc atagtttcaa ctgcaaaagc tgctaatgta attttaaaaa tgtgggatag
     6961 aaaagagaaa actactgctg acttaatagt tgttgaaggt ccaaaagctg gtggtcacct
     7021 tggatactct aacgaggaac ttgataacat agattctata gactatgata aggaatttgt
     7081 tgaaatttta aaggttgcaa atacttatgg agaaaaattt ggtagaaaca taccagtagt
     7141 tgctgctggt ggtataactt ctagtagtga tgttaaaaaa tatatagata tgggtgcaag
     7201 tggtgtacaa gttggtacaa gatttgttgc tacttacgaa tgtgatgccc atgagaactt
     7261 taaaatggca tacataaatg ctagtgaaga agatgttcat atagttaaaa gtcctgtagg
     7321 tcttcctgga cgcgccataa gaaacaaatt tatagaagaa gttaaaataa atcgtccaga
     7381 aataaagaag tgctataatt gtttgattcc ttgtaatcca aaagaaactc cttactgtat
     7441 ttctcaagct ctaatcaatg cagttaaagg agatgttgaa aattcacttt tattttgtgg
     7501 aaatgatgcc tataaaattg ataaattaag tactgttgaa gatgttatca atgaattgat
     7561 ttctgaatta taatttaaag aaaactaaat taaaatttta tcaagctaag gagtttaaat
     7621 acgttattta ttaatcttta taaacatatt tatgtcctta gcttttttgt gtcaatttcc
     7681 ttttatggaa attttaattt aattagagat agtattaacc tttataacta atcttctttt
     7741 acaagtacat tggttatttc agctatatat aaagtatgat aatctttttg tggataccat
     7801 cttccatcta taccttcagc aataaaacat tgaggttcaa gtttctgact atacattttt
     7861 ttgcatataa tagccatttt agattcttta aaataaggtg tatcatttaa gtgttctata
     7921 ttaaatccaa tctgtgatat cttatcctct tctctaccag atacctttcc acaatatgaa
     7981 agctctttac gaaaatcttc atcaaaaaat gtaagagaaa atttatctgt attatctata
     8041 aattccttag tataacgctg tggtcttatt actacaaaag caacatcttt tccccacata
     8101 actccaagcc ctccccagct agcagtcatt gtattcactt taccttcatt ttctgctgtt
     8161 ataagtgtcc aatctttacc tatcaatcca aatggattat ttttaatctc ttctgccaaa
     8221 atctctttaa aatcactcat atctctaata acctctcatt ctcttatatt tatattcctt
     8281 ttattttcgt gataaattat aaatgaagtc tagttttgaa aataaaatac ttttttaaat
     8341 atattattgc a
//
LOCUS       DAYAKB010000122         8017 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.123, whole genome shotgun sequence.
ACCESSION   DAYAKB010000122 DAYAKB010000000
VERSION     DAYAKB010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8017
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.123"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            50..1327
                     /locus_tag="ACGI3L_003471"
     CDS             50..1327
                     /locus_tag="ACGI3L_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFG9199163.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASFNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            1510..2232
                     /gene="yqeC"
                     /locus_tag="ACGI3L_003472"
     CDS             1510..2232
                     /gene="yqeC"
                     /locus_tag="ACGI3L_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium cofactor biosynthesis protein YqeC"
                     /protein_id="HFG9199164.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRNKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHRTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            2339..2908
                     /gene="mocA"
                     /locus_tag="ACGI3L_003473"
     CDS             2339..2908
                     /gene="mocA"
                     /locus_tag="ACGI3L_003473"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070567 - cytidylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HFG9199165.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            2905..3924
                     /locus_tag="ACGI3L_003474"
     CDS             2905..3924
                     /locus_tag="ACGI3L_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HFG9199166.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            4262..5887
                     /locus_tag="ACGI3L_003475"
     CDS             4262..5887
                     /locus_tag="ACGI3L_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9199167.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALLNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            6086..6562
                     /locus_tag="ACGI3L_003476"
     CDS             6086..6562
                     /locus_tag="ACGI3L_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199168.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(6770..7882)
                     /locus_tag="ACGI3L_003477"
     CDS             complement(6770..7882)
                     /locus_tag="ACGI3L_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9199169.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
BASE COUNT         3233 a          810 c         1327 g         2647 t
ORIGIN      
        1 aataccgtat ataatgtcta gtagagtata ttctaaagga ggtgagttca tgtcaaacag
       61 aataaaaaat atacactatg gaactcagag acaacaatta aaaaacttaa ctaaaaaaga
      121 atatcaagct ctacgagaga tgtgcttctt agctaagaac ttatataatg ttggtacata
      181 taatgtaaga cagcattatt tcaatcaagg agaacatctt aactatgaag ctaattatca
      241 tgtatgcaaa gaaaatgaga actataagct tctcaatagt aatatagcgc aacaaatatt
      301 aaaagaagta gacagttcgt ttaggtcatt ttttggatta attaaattag ccaaagaagg
      361 aaaatatgac tttagaggga taaaatcacc taaatattta gataaagaag gattttttag
      421 cataataata ggtcaaataa gaatcaaaga agatgggatt ttaaatgtac ctatgtctcc
      481 agcatttaaa aaactatatg ggaaagtaag tataaaagtt ccacaaaata tactagagaa
      541 aaaaattaaa gaaataagaa taatacctaa acataaagct aggttctttg aaattcagta
      601 ttgttatgaa ataccaaaat cagaggaagt ttcaaatcaa aaaaatgcac tagctataga
      661 cttgggttta gaaaatttat gtacatgtgt taccaattta ggtgatagtt ttatcataga
      721 tggaaaaagg ctaaaatctg tgaatcagtg ggcaaacaaa cagaatgata aaatagaagc
      781 cttaaaatta aaaaagaata taactgcaat aacaagaaaa caatttaaag tttggaataa
      841 gagaaataat caagttaaag actatgtaaa taaaacctgt ttttatataa ttgattattg
      901 tgtaaaaaat aatattggaa atttaattgt aggatataat gctaagttag aaaaaagtga
      961 taatatggag agaaaaatat atagaaattt tataagaatc ccatttggag agataaaagg
     1021 aaaattagaa tatctgtgta aaataaaaaa tatcaatttt attaggcaag aagaaagcta
     1081 tactagtaaa tcagattttt ttgctgatga ttttctacct gatatcaatg tggacaatgt
     1141 taaaaaatat gactttaaag gggaaagaat aacacgtgga cagtacaaat ccagtgttgg
     1201 aatcattata aatgcagatg taaatgcgag ttttaatata ctaaaaaaat cacaagtagt
     1261 taatttatct aatttacaga ataatcctca aatattaaag caaccacaga gagtaagaat
     1321 atcttaatta tatttaaaag ataaactgat agcgtaagct tacagcttag cggcgaattg
     1381 gatccgcctt gttgtttaca acagaatcta tttactttcg agtttatgga atttcaaaaa
     1441 tcacttttac taaaaaggcc taactataat aattaagaga ttagaaaact ggttataaga
     1501 ggtgaaagtg tggaactatc aaatataata gaaaagaatg aaataataac tgtagttgga
     1561 gcaggaggaa aaacttcgtt tataaactat tttgcaaatt tttatagaaa taaattgaaa
     1621 gttcttctta caacaacaac taaaatatat gtaccaaacg attatgacaa tataattatt
     1681 acaatagatg gaactgttat tccatctatt tgtcatggaa taacagtctg tggcagttat
     1741 ataaataatg aaaataaatt agtaagtatt gattcctcta ttttggatga aattgtagac
     1801 caatttgatt tagttttaat agagggagat ggctcaaaga gaaaaaaact taaaggttgg
     1861 aatgctaaag aaccagtagt atatcataga actacaaaaa ccatagggat attagatata
     1921 acatcatttg gaatgaatat taatgaagag aatatacata gagtagaaat atttaaaaaa
     1981 atagcaaatt tagatacaag tagtattaat agtagttcta cagtaagtat tgaaaactta
     2041 aaaaatatag tattaaatcc aaatggatta tttaaaaatt attctggaaa aagagtatta
     2101 tttattaata aagttgaaaa tgaaaaatat aaaaatttag ctataaaatt aatagaaaat
     2161 attaaagaat atgaaagtga aatagagata ttttatggaa gtgtaaaaca aaaattttgt
     2221 gtaagatatt gaagtattaa aatagtttat atgatattat atatatagat aatatcaata
     2281 gagatattat aaaaatcata gaactatcaa tatattataa ataccaagga tgatatatat
     2341 gataaatgca gtgataatgg catcaggctt tgccagaaga atgggagcaa ataaactttt
     2401 attaaattat aaaggctgtt ctataataga acatgtattt agagaagtta gcaagattga
     2461 ttttcatcaa gttgtagtag taagtcaata tgaagaggtt ttgttattgt gtaataaata
     2521 tggttttgaa tatatagata ataaaaatgc aaatataggt caaagtgaat ctataaaatt
     2581 aggagtttta aatagctcaa aatgtgatgg ttatatgttc tttgtaggag accagccatt
     2641 tattgataac ttatatatag ataaaattat aaatactttt aaattagata gagattttat
     2701 agtaattcca agatacaaag atatgtgtgg aaatccagtc atattcccat atagcaagaa
     2761 agaagaattg ttggcactta aagaagatga aaaaggtaaa accattttaa aaaattcatc
     2821 aaaaataaag tatgtagaag ttcctaaaga aatgttattt gatatcgata caaaaatgga
     2881 ctatgagaga attgggggta aattatgaag ctaataaaaa ctatagatgc tgttggacaa
     2941 gttttatgtc acgacataac tcaaataata cctggagaat ttaaaggaag aaaatttaaa
     3001 aagggtcaca tagtaaaaga agaagatatt ccagtgttat tatctcttgg taaagataat
     3061 ttgtatgtat gggaaaagtc agaaggaatg gttcatgaaa atgaaggcgc attgttttta
     3121 aaagaactaa ctgctggaga aaatttagat tttagtgaaa taaaagaagg gaaaatagat
     3181 tttatagcag catgtgatgg tctattaaag atagatgttg atgcactttt tgatttgaat
     3241 tgtgttggag aaataatgat ggctactctt cataataatt ttatagtaaa taaaggttta
     3301 aaagtagctg gaacaagagt gataccttta gttatagatg agaaaaaatt agaagatgca
     3361 aaaaaagtag ttggtaatag aaaaatagta aatgtagtac cttttaaacc taagaaagta
     3421 ggaattgtta ctacaggaaa tgaagtgttt tatagcagaa ttgttgataa atttggacca
     3481 gtaatagaag aaaaagtaaa aggctttggt tgtgaagtta taggacagac tatatgccca
     3541 gatgataaag aaattataaa gagtgcaata aaagaattta taagtcaagg agcagaactt
     3601 atctgttgta ctggtgggat gagtgtagac ccagatgatg ttacgccaac agctataaaa
     3661 gaaactggag ctgatttagt gacatatggt tcaccaatat taccaggagc tatgttttta
     3721 cttgcttatt acggagaagt tccaattatg ggtataccag gatgcgcaat gtatcacaaa
     3781 actacagtat ttgatatagt tttatctagg gttttaattg atgaaaagct tgataagtat
     3841 gatatagcta gatatggtca tggtggcctt tgtatgaact gtgatgtatg tacttatcct
     3901 gcatgtaatt ttgctaaaat ataaagttat taaaaaagag tatttacaaa ttaagtactc
     3961 tttttaaata tgaaacaaaa cagctagaat gatgttttaa aaaaagcata tttatttaga
     4021 aattataata acttattttc aatgtgtaaa agaatgaata aagttgcaat ttgatttctt
     4081 tataagtata atataagaga ttgttaattt ttataaattt acaattttta gtattatttt
     4141 aataaatatt tcacaaattt agtataaaaa atatactatt tacgtgataa tatataataa
     4201 aaatgttatc aaagttttat gataaaataa attatgagca aaaagaaagg aaaatatatt
     4261 aatgttacaa gttacaggtg ttggacttag atttggtgat aaggaactat ttaaagatgt
     4321 taacttaaaa ttcactaaag gtaattgcta tggaataata ggagctaatg gtgcgggaaa
     4381 atctactttt ttaaaaatat tatcaggaga aatagagcct aatacaggta gtatatctat
     4441 aactgataaa gaaagaatgt cagttttaaa acaggaccac tttgaatatg aagaagaaac
     4501 tgttttaaat gttgttataa gaggtcatga gagactttgg aacataatga aagaaaaaga
     4561 tgcattgtat atgaaggaag actttaatga agaagatggg ataaaagctg ccgaacttga
     4621 aggtgagttt gcagagcttg acggatggga tgcagaaact aatgctgaga aaatacttat
     4681 gggtcttggc ataacgaaag atatgcatta caaacaaatg aaggaactag ttggtgggga
     4741 aaaggttaag gtattgttag cacaatcact ttttggtaag cctgaaatac tattaatgga
     4801 cgaacctaca aaccacttag attttaaatc aataaactgg ttaaataatt ttataatgga
     4861 tttagaagaa tctatagtta taatagtatc acatgataga catttcctaa atcaaatatg
     4921 tactaatata gttgacgtag attttggtaa aatacaaatg tacgttggaa actatgattt
     4981 ctggtatgag tcaagtcaat tggctttaca attggctaag gaccaaaata aaaagactga
     5041 agaaaagata gctcaattaa aggaatttat agctagattt agttctaatg cttcaaaggc
     5101 taaacaagca acatcaagaa agaaacagtt agagaaatta gaagttgaag atatacaacc
     5161 atcaagaaga agatatccat atgtaggatt tacacctgca agagaaattg ggaatgaagt
     5221 tttagaagta cacaatttaa ctaaaactat agatggggtt aaggttcttg ataatgtgtc
     5281 atttagattg gatagagatg ataaagtagt atttatggga gatgaaatag ctactactgc
     5341 acttttaaac atagttatgg gagaacttga accagacagt ggagagtata aatggggagt
     5401 aactacttct caagattatc ttccaaaaaa tcataataag ttttttgacg gagtagaata
     5461 ttctttggtt gactggctta gacagttctc tgaagaaaaa agtgaaagtt ttataagagg
     5521 atttttaggt agaatgttat tctcaggtga agaagcatta aaagaagctc aagttatatc
     5581 tggaggagaa aaggttagat gtatgcttag taagctaatg ctttcaaatg caaatgtact
     5641 tgtattagat gaccctacta accacttaga cctagaaagt ataacttctg taaataaagg
     5701 acttgaaaag ttcccaggag tgcttttatt tacttctcat gaccatgaat ttatatctac
     5761 tatagcaaat agaattatag agataactcc aaatggaata atggatagaa aaatggactt
     5821 tgatgagtat ttagaaagta aagagataca agaccaatta gctaaaatgt atggaaaaga
     5881 taaataatta ttagtataaa accttttaat atttgagaca tgctatgcat gagtgtgtaa
     5941 atttttaatc aaatattagg aggtttttta tattgtttaa acatgtttat tagcagaata
     6001 gagtaatatt ttgtatatta agaatttaaa tataatatag tagatgatat aataaaaata
     6061 tataacattt tggggggaat agattatggt taagaaaagg ttagtagctg tagtaattag
     6121 tttagctatg attagtgtag ggaatttttc atatgctcac tcaggagggc ataattcatc
     6181 aggaggtcat cataataaaa ataaatcaga gttaacacgt tattattgtg gaggacattc
     6241 agcacatcaa cacaataaag gtttttgtcc ttatgctagt acaaaagaaa attctggagt
     6301 aacaatatct tcagtacata acgaaaaaaa tcataaaaac tattttgcag aaaaagggta
     6361 taataaaggt tatgaagatg ggtgtaaagg gctttataat ttaagtgtca cagaagccaa
     6421 atctgataat ttatatgaaa aagagatttt aaaaagttca tatgaaaaag gatatttaat
     6481 tggatacaat gaatataaag caaaaaaagt agatgatgta atgaagaaga tgttagatat
     6541 tccaatgtta gcaagtatat aataatatag tatttaaaaa gatattttct ataagggaat
     6601 atctttttta ttgtaaagta taatttttcg taaaaaagta taataactga ggcgataaat
     6661 taaaataaaa cagattattt aagtagttat taatttgaga tagatacatt taatattaat
     6721 gaatctatct caataagcta agctaattta aagctaagat aaattaatat taattagcat
     6781 taaataaact ttcagaaatt ttgtcagaag cctctttatc catttcttta agtacatgag
     6841 aataaacgct tagagtagta cttatatttg agtgtcctac tctctcggat ataaccttta
     6901 taggtacttt agaatttata agtaaagtaa catgtgagtg tcttaaatca tggaatctaa
     6961 tatgaggtaa ttcattcttt tctaaaaatc ttttaaattt tttactcata acatcttcag
     7021 caataggttc acatttctta ttgaaaaata acaaattatt attatttcta atggaagatt
     7081 ttaataaatt tttattctgt tttattttat attcttttaa taaagacatt aattctttgg
     7141 gagaagatat ttttctaaca gagctttctg tctttggctc tttgagaata acagaaccat
     7201 taattcggga agttatctta tttactgtta ttgtattttc ttcaaaatca atattatccc
     7261 aagttagacc taaaacttct gaaattctaa gacctaatcc aatagccaaa ttaataggta
     7321 attccatttc tgtatttttt gctaaatcta ataattttat catttgttct ctatcataaa
     7381 tctcattttt aaatttttta tatcttggag cctctatact atccataaca ttttctttta
     7441 ttaatttgag tctataagct ctttttattg caagtttcaa tatatttata tgaatcttaa
     7501 ttgattgagg atttagttta taagatagtt tatctatgta gttttgtatg tgaaccggat
     7561 gtaagtcttg tattttatat tttccaatag atggattaat gtaattctta caaatactaa
     7621 cataattatt atatgtagct aaagatatat tttcactata tttatttaga aaatctaata
     7681 gaaattctga cactgtaatt tcgcttggta ctaaaaaacc atcattatat aagctttctt
     7741 ttacctcatt tagtctttta cttgcttccc tttttttatc aaaagtaccc atattttttt
     7801 gttttctttt acctgtcttt tcatcttcaa attccaggta aacaacatag tttttatttc
     7861 tttttctaat aaatgcattc atatataacc caccaatcaa aattttatac atttattata
     7921 acatatatat atcacaaaat aattttgaaa tagagttgca tacattttaa tacattgtat
     7981 atatttattt aaaaaatgta tatattatgt caaatat
//
LOCUS       DAYAKB010000123         7971 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.124, whole genome shotgun sequence.
ACCESSION   DAYAKB010000123 DAYAKB010000000
VERSION     DAYAKB010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7971
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.124"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(195..950)
                     /gene="dapB"
                     /locus_tag="ACGI3L_003478"
     CDS             complement(195..950)
                     /gene="dapB"
                     /locus_tag="ACGI3L_003478"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFG9199170.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1390..2379
                     /locus_tag="ACGI3L_003479"
     CDS             1390..2379
                     /locus_tag="ACGI3L_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFG9199171.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2831..3547)
                     /gene="dapD"
                     /locus_tag="ACGI3L_003480"
     CDS             complement(2831..3547)
                     /gene="dapD"
                     /locus_tag="ACGI3L_003480"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFG9199172.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3771..4520)
                     /gene="dapB"
                     /locus_tag="ACGI3L_003481"
     CDS             complement(3771..4520)
                     /gene="dapB"
                     /locus_tag="ACGI3L_003481"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFG9199173.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4587..5474)
                     /gene="dapA"
                     /locus_tag="ACGI3L_003482"
     CDS             complement(4587..5474)
                     /gene="dapA"
                     /locus_tag="ACGI3L_003482"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFG9199174.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5591..6592)
                     /locus_tag="ACGI3L_003483"
     CDS             complement(5591..6592)
                     /locus_tag="ACGI3L_003483"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFG9199175.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     regulatory      complement(6765..6939)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(7017..7898)
                     /gene="dapA"
                     /locus_tag="ACGI3L_003484"
     CDS             complement(7017..7898)
                     /gene="dapA"
                     /locus_tag="ACGI3L_003484"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFG9199176.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
BASE COUNT         2727 a         1288 c         1034 g         2922 t
ORIGIN      
        1 gatgaagaga ttataaaata ataaacaata taattccata taccaataaa taagataatc
       61 tttaagaaaa atgattatat ttaaaaggta aacataaaat ttataaactt ttagaataga
      121 aatctcaatc aattagatat tcaaattgat gaatatgaat acctaaatag attgagattt
      181 attatgtaca aaacttatcc taatatatct gacattttat aaagcccaga ttgcttacca
      241 attaaaaatt tagctgcaac tatagaaccg tttgcaaata cttcatcaga ttgagaatga
      301 tggcttaatg taagaacttc attatcacct gcaaatacaa catcatggtc gctgattata
      361 ttgccacctc ttatagagtg tattccaatt tcatttggtt ttcttttaca atctctacca
      421 tatctaccat gtgtattttc actttcaggc aagacttctc taattgcatt agctatcata
      481 gtagcagttc cactaggggc gtcttctttt ctattgtgat gtttttctat gatttcaata
      541 tcaaaacctt ctaacatctt tgaagcatcc ttaactaatt ttattaatat attcactcca
      601 agagatgtat ttgatgataa taatatagga atgttttttg atgcttcttc tattttattt
      661 aagtcatttt catcatatcc agtagtagct aatactacag gtgtattatt ttttagagca
      721 tatgacaata ttggctctaa agtctcatga tgtgaaaagt ctattattac atcagttttt
      781 tcagttacat cagtcattgt tttgtaaagc tttgtatcac tatgatgacc tttttcatca
      841 gcagacctag ctacaccaca aaccaactct aattcattat ctttttttac acattctgct
      901 aaaactcttc ccattgttcc attatagcca ctaattataa ctttcaacat aaattcctcc
      961 tatgaaatta ataaaaattt gttatatttc tataagttta ttttatcact aatataattt
     1021 atataaaata atattagtga taataagctt acaatttatc ttacattaaa aaatttaagt
     1081 ggatttttca aaatatagat aaatttcttt ttcattgtat aaatgataaa aatatatttg
     1141 acttcatacc aaaaagagtg ccccatgaac taaaaagtta attttgaaat accatattca
     1201 tatatcatat gatttatttg gaaatcaata ttaatacatt aaaataacta aatacatgta
     1261 tgcataaaga tgtataaaaa atatataaac atatagtatt aattttaaat tcaacaattt
     1321 aattgttaaa agtgttatta ttaaattaga aatatcttaa cttaatatac tgagatggga
     1381 gtgatagata tgttaaaaga agaaaaaact tatcaagaga aagacgcaaa agtattcaat
     1441 ggagtggcag ctttgataat gattttatta tttttagtag tttcaatagg tatcatggtt
     1501 tttgggatag taaaacttga tagtggattt actggaatag gttcacttat gttaattttg
     1561 ggacttgtat ttatagtagt agattttatc ctattttttg ggctaaaaat gattaatcct
     1621 aaagaagcta tagttctagt tttgtttggt aactattatg gaactataaa aaaagaaggg
     1681 tactattggg tgaatccatt ttgttcagca ataaacccag cagtatcaag aattaatgta
     1741 tcgaaatctt catctgatga aaaggtagat atatcaacta attcaagggg caaaaaagta
     1801 tctttaaaaa caatgactct taataatgaa aagcagaaag tcaatgattt attgggaaat
     1861 ccaattataa taggagtggt tgtaatttgg aaggttatag atgcaacaaa ggcagtattt
     1921 aatgtagata attataatac attcttatct attcagtgtg attctactat tcgcaatgtt
     1981 tcaagacttt atccatatga tgtatctgaa gatggagatg aaaaatctct tcgtggtagt
     2041 agtcaggaaa tagcagatag attaaaagat gaattacaat caagggttga tattgcagga
     2101 attgaagtgt gtgaagtgag aattactcat ctttcttatg caccagagat tgcagcagca
     2161 atgttacaac gtcaacaagc agaggctata atagcagcac gtaaaaagat tgttgagggg
     2221 gctgtaagta tggtagagat ggcattgact aatttaagtg aaaataatgt tgtgactttg
     2281 gacgaagaac gtaaagcagc tatggtaagt aatctgttag ttgtgctttg tggcaataaa
     2341 gatgcacaac cagtggtaaa cagcagttct atttattaaa ttataaaaag tttaatagtt
     2401 tattttattg atatatagaa aatttagtag ttcattttat taaattatag aaagattaat
     2461 ggtttgcttt attgaattat aaaaagttta ataatttatt ctattgatat atagaaaatt
     2521 tagtagttca ttttattaaa ttatataaag attaatggtt ttcactttat taaattataa
     2581 aaagtttaat agtttattac attgatatat tgaaaaattg aaggaaataa aaatacttgt
     2641 cagcaagaaa taaaaatgat ataagaatga ataagagaat tgtaaaaaaa taaaatgatt
     2701 ataaataaaa gataaaaata ttgtaaaaaa gagggtgcct ctggtgaatt aaattcacac
     2761 agagacacct ttttaattaa ttttttaaat tagtatatta ttgtttaatt aatagtatag
     2821 tactatttaa ttaatctaaa tttctaaggt cttccataag cttagttttg tcagccgttt
     2881 tttcatcttt catttttata actttagcag gagaaccagc aacaacggca ccagcttcta
     2941 catcagtagt tacaacagca ccagctgcaa caacagcacc tttaccgatt ctaacacctt
     3001 caagaataac tgcattagct cctattaaaa catcatcttc aactataaca ggagtagcag
     3061 aaggtggctc taaaacacca gcaacaacag caccagcacc taagtgaaca tttttaccaa
     3121 gagttcctct agctccaata acagcattca tatctaccat agaaccttca ccaataacag
     3181 ctcctatatt tataacagct cccatcatta caacagcatt tttttctata gtaaccatgt
     3241 ctcttattat tgcacctggc tcaattcttg catgttcact taaagtattt tttagaggaa
     3301 tagcagaatt tcttctatca tattctacat gagtatctgt tatatcattt ccatgtttat
     3361 ctaatacttc cattatatcc tcatagtcac ctacaaatat ataagaacca ttacttccga
     3421 ataccttaaa tttatcagtt gattggaagt gtaaagagtt agtatttaca tataccttaa
     3481 caggtgtttt ctttttaact tcttttatat accttgctat ttcataagca tcgtttaaat
     3541 ttaccatttg ttaattctcc ttgtatttca ttatatttct tttattatat acttatttgt
     3601 caattttagt atatacttac ttcttattat ttatatttta ttttagttag tttttattgt
     3661 atagacatag tattaaataa atttattata tatgtttgat ttgtattgcg tattattata
     3721 tctatattgc atatgtttaa tttatattgt gtattattat atttatgcta ttatcccaac
     3781 atgctgtcca tattataaaa tcctggtttt tgcttaacta agtatttggc agcagctata
     3841 gaaccacttg caaagatacc acgagattga gcttgatggc ttattgtaag aacctcattg
     3901 tctccagcaa atagagcatc atgttcgcca acaatatttc cacctcttat agcatgaata
     3961 ccaacttcat ttggttgtct ttttgcacta cgaccatatc taccataatt attttcaacg
     4021 tttggcaaaa cctcttttat agcgttagca atcataacag ctgtgccact tggggcatct
     4081 acttttctgt tgtgatgttt ttctattatt tctatatcaa atccttctag taatttagct
     4141 gcatctttaa ccaattttac taatacattt acaccaagag acatattata tgattggaat
     4201 acaggaataa ctttagccgc ttcacgtatt ttgttcattt cgtcatcatt atatccagta
     4261 gtagcaatta ctaaaggtgt tttagtcttt aaaacgtaag ataagatatt atctaaatta
     4321 gagtgatgag aaaaatctat aactacatca gcttcctcaa ctatagtact catatcttca
     4381 taaattttaa ggtcgccttc atagctatcc agacctctag ctgcaacaca aaccaattct
     4441 aattcattat cttctcttat agtatcggct aaaatcttac ccatttttcc atcataacca
     4501 gttgctataa cttttaacat aatttcctcc tatgattaag ggctaacttt tgaccaaact
     4561 tactttttac catgcattaa tctttactat gcattaactt ttagcccaaa gttaactaat
     4621 tctttcttta atacttctaa atttgctggg tccatttctg ctagaggtaa tcttaaatct
     4681 ccaacattga atcccaataa attcattgca gtcttaactg gtataggatt tacttctata
     4741 aataaagctg cgattagagc atccatacca agttgtaatt ttctagaacc ttcaatatcg
     4801 ccttcaaaga atttagctac caaatcgtga gtttcttgag ggcaaacatt agcaagtact
     4861 gatataactc cttgacctcc taaagataat aaaggaagta tagtatcatc attaccagag
     4921 tagatagcaa agtcatctgg aactaaacta gctatttctg caacctgtcc taggtctcca
     4981 ctagcttctt ttacagcaac tatgttatca attttagcaa gttcaactat aaggctagga
     5041 cttatattta cacaagttct tccagggaca ttgtaaagta taattggaag tttaacactg
     5101 ttagctattg tttcaaaatg acgcttaagt ccagctttat tagctttatt gtaataaggt
     5161 gttattatta atagagcatc tactcctaat ttttcagctt cttgacttaa gttaactgag
     5221 tgcatagtat cattagaacc acttccagct ataacaggaa ctcttttatt aactttttca
     5281 acaacatact taatagtagc aagttgttct tcatcagtca tagtattagc ttcaccagta
     5341 gtaccacaag atactatagc atcagtacca ttagctattt ggtattcaac taattcacct
     5401 aatttgtcaa aatcaacttt gttatccttt gtaaatggtg taactagagc aacagcagaa
     5461 cctttaaata tcatataaaa tcaatcccct cttttttatt tttgtgtttt atattacagt
     5521 tacttctaat gcttgttttt gagttactat taatatttta caaaattata tatttataca
     5581 agtttgtata ttatactaaa tcgtatgata aagccatttc agctatttga attgcgttag
     5641 ttgcagcacc ttttcttata ttatcagcaa caacccaaag atttacacca ttatcaacac
     5701 taaaatctct tcttattctt ccaacaaaca cttcatctct atcatcaaat tctacagcag
     5761 ttggatattc gtttttagca ggattatcaa ctactacaac acctggagct tcttcaagtg
     5821 tttttactaa atcatctaac tcaaatggat tgttaaactc aacatttata gattcactat
     5881 gaccattttt tactggaact cttacagtag ttgcagttat ttttaaatcg tagttatcaa
     5941 gtattttcat agtttcattt accattttca tttcttcttt agtgtatcca ttttcagtga
     6001 atgaatctat atgaggaaga cagttgtaag agatttgatg agggtagaat ccagtaggat
     6061 taccgttcat tcctttctct aaatcttcaa cacctttaac accagaacca gatacagctt
     6121 ggtaagtaga gtaaacaact ctcttaattt tgtatttatc atcaagagct ttaaggggaa
     6181 ccatagcttg tatagtagag cagttaggat tagctattat acccttatga ttttttatgg
     6241 cttctggatt aacctcagga actactaaag gcacatctgg attcattctc cattgactag
     6301 agttatctac tactaagatt ccatttgaag cagctattgg agcatacttt tcactaatac
     6361 ttccaccagc agagaataat gctatttgta tgcctctatc agtaaatgaa gtttccttta
     6421 attcttctac tatatattct ttaccacaaa acattacttt agaaccagct gatttagaag
     6481 aagagaataa aaatagattt tctattggaa aatttctttc ttctaatact tttaaaaatg
     6541 ttctacctac cattccagta gcaccaacta ttgctacatt tacttttttc atataaattc
     6601 accccaattt taaattatta aaacattatt ttattttagt tatacaagta agatatgtta
     6661 atatttttat atatccaaaa actttaatat tatattaaca actttaatta tatacaaaaa
     6721 acgtacaaag gtatactttg tacgtctaat ttatcactca aagtaaaccc tgtagctcat
     6781 cacctacaaa aataagtgac agtattacac atgttatgtg caatcccaga aaatattatt
     6841 gcaagaaata ttttcttcgg ctgtaaatcc tttttccaat cattaacacc tgccagctac
     6901 tattggatac tcttagttac agctacctct accctaggtt aataggatat taaaatttga
     6961 ttattctaat aataatacat atttaagaaa aaatcaactt atttatataa atattgctaa
     7021 aatttaaatc caaaatttgt caattcttgt tttaacacat taagattagt ttcttccatt
     7081 tcagctagag gaagtcttaa atcaccaaca ttaaaaccta aaatgttcat ggcagtttta
     7141 acaggaactg gatttacttc tataaataaa gcagcaatta aagcatccat atcaagttgt
     7201 aatttttttg agccttcaat atcaccttca aagaatttag ttactaaatc atgtgtttct
     7261 ttaggacata tgttagcaag tacagagata acaccacttc cacctaatga taatagtggt
     7321 agtatagtat catcattacc ggagtatata gcaaagtctt taggtactaa tttagctatt
     7381 tctgcaactt gagctaagtc tccacttgct tccttcacag caactatatt atctatttta
     7441 gcaagttcag ccacaacaga tggctttata ttcactttag ttcttcctgg tacgttgtat
     7501 aaaataattg gcaacttaac gctatttgct attgtttcaa agtgaagttt aagacctttc
     7561 tcattagtct tattatagta aggagttatt attaaaagac catccacccc taatttttca
     7621 gcttcttgac tcatatgaac agacaacata gtattgtttg aaccagtacc tgctataaca
     7681 ggtattctct tattaacttt ttcaactgta tattttatta cagcaaaaat ttcagattca
     7741 ctcatagtag tcgcctcacc tgttgttcca caaacaacta gtgcatctgt gccattctca
     7801 atgtgatatt cgattaattc acctaatttt tcaaagttga cattattatc ctctgtaaat
     7861 ggggtaacta aagcaacagc agaaccttta aataacatat aatcaaatct ccttttttat
     7921 ctaaatttaa ttttttaagt acaataataa ttatagtaca aattaattaa t
//
LOCUS       DAYAKB010000124         7969 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.125, whole genome shotgun sequence.
ACCESSION   DAYAKB010000124 DAYAKB010000000
VERSION     DAYAKB010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.125"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(102..1373)
                     /gene="sleC"
                     /locus_tag="ACGI3L_003485"
     CDS             complement(102..1373)
                     /gene="sleC"
                     /locus_tag="ACGI3L_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic germination protein SleC"
                     /protein_id="HFG9199177.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            1618..2334
                     /locus_tag="ACGI3L_003486"
     CDS             1618..2334
                     /locus_tag="ACGI3L_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HFG9199178.1"
                     /translation="MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            2413..3723
                     /locus_tag="ACGI3L_003487"
     CDS             2413..3723
                     /locus_tag="ACGI3L_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFG9199179.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            3823..4359
                     /gene="lepB"
                     /locus_tag="ACGI3L_003488"
     CDS             3823..4359
                     /gene="lepB"
                     /locus_tag="ACGI3L_003488"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFG9199180.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            4525..5061
                     /gene="lepB"
                     /locus_tag="ACGI3L_003489"
     CDS             4525..5061
                     /gene="lepB"
                     /locus_tag="ACGI3L_003489"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFG9199181.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            5071..5826
                     /locus_tag="ACGI3L_003490"
     CDS             5071..5826
                     /locus_tag="ACGI3L_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HFG9199182.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EILTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            5900..7567
                     /locus_tag="ACGI3L_003491"
     CDS             5900..7567
                     /locus_tag="ACGI3L_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HFG9199183.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
BASE COUNT         2973 a          829 c         1494 g         2673 t
ORIGIN      
        1 ttataagtaa tacttatggt atatattagt tcataacagc cacttttatt ttaaattaat
       61 aattttattc aataatttga gtttatgttc taaatcaagc tttaaattaa aggatttaaa
      121 gaagctattc tagttgtagc tacataaact ctggatattt cataccatgt tttaaaatct
      181 actactccgc tttgaggtaa accaaagatt ccttggaata tcttaacagc gttttctgta
      241 tctgttccat agataccatc ttctataact tttggtacag ctggataaga attagatata
      301 gcatttaact gattttgtat ggttctaaca tactgcccag aagaaccaac ttgtagtgta
      361 gtaccaggga atgacactgg tacaccactt actataggtg ctctttcaaa tactatctca
      421 tctccataga aatatcttag tatactctca tagtcatatc cttggtcacc taagtcttta
      481 ctgccccatt gagtcatttg gtcaggacat tgggattttt gtccatcaca atattgtgct
      541 aatagtggct gtcttgatgt aggaggtctt tttataaaag tattaaaaat agcatctaca
      601 actacgttaa ttggttcaaa taagtttcta ttatttataa acttatggtc gtatgctgtt
      661 gttgaagtta ttgtaaagtt atatccttta tttctatacc attcagtaaa gactctattt
      721 aaagtaaatg atattatagc tattacattt gcatagattg tctgttcagg ccaagttgaa
      781 tatatttcag atgacgctat gtttttaatg tactctttaa atggaatcca atagtttgga
      841 gctgatgaat cttctggcaa accatcatga actactataa attcaggcac tacggggtta
      901 tctaatacaa cgaaaccagt aggaggtggt aatggtttta agttactttc tggaatctta
      961 ggaggataag taccatatag agtatgttct cctatatcaa aaatcaactc actttgtctt
     1021 gagaaagaac gcttacttct tgttctagga gacatgggaa ctccttgtct tgcttcaatt
     1081 gtagctaaca actgtgttcc ttctatgaca actgtctcat atccatctgc tatggcttcc
     1141 actatatact ggctataagg tctaacatca gatggttgta gagagtaatc tacatctggt
     1201 gctggtaata ctaaaccagt cacttgacca gattcattac ttcttaggtt ttggtataaa
     1261 gttgatgagc tttggctacc attagacatt gaatatatgt ttactactgc attttgaata
     1321 ggtctattgt tagtagcatc aattatgctt actgttaaga aaccatcttg catcaaatca
     1381 ccctttcttt aaatgaattt agttccctta tatttcaaga tatgaatata gcttgaaatt
     1441 tgttaaataa tatagatata aatttaaatt tttttgagta tttgagtata tttgtattta
     1501 aataatttaa aataatttaa tgtatatttt agtatgtatt taaaacacga ataagttaaa
     1561 aataagtaga tgatataaat cataaataaa tcaaaaattt tgaaaggaaa ataatctatg
     1621 aagctagatt tatttttatt agcaataatt cctatattga tagggatgtt ttggataagg
     1681 tctaaagata gatattgtag agaaccccta atccatctaa ttaaattttt tttaataggt
     1741 gcttttctaa gtgttataat tatactttta gaaaatttac tgatgaagtt taatgtattt
     1801 gaagggtatt cagaactaat atatgtatca tttgtagttg caggacttgt agaagaaggt
     1861 gtaaaagctc tgatactgat tcctgcccta attaaagaaa aacactttac tgaaaagtta
     1921 gatggtatta tttactctgt atttttagct ttaggatttg caacaattga aaatatggtt
     1981 tatatttttt ctgaaagtag aaatctagca ctgcaagttg gtattaatag ggcagttatc
     2041 tctataccag ctcatgtaat gtttgcaatt actatgggct actatatttc taagtataaa
     2101 tttgagggaa ataaaaataa aagacgtgag tatttgttta tggcggtgtt aattccaatt
     2161 ttattacatg gagtttttga tttcatattg atgatagaat atagatgggc tattatatta
     2221 cttatagttt atgtaataat tttgtggaag ataaatcttg ataaacttga gaaatatatg
     2281 aatcactcta aaaaagtgtt tttcggtaat cttaggaaaa agaagaagaa ataaaattta
     2341 aaggaaagac ataaataatt aaagtataat aaatgacaca caagtaaagc agattgaagg
     2401 gggattatag atttgacaga attaccaaag gaatttttag aagatattga agaaatacta
     2461 aaagatgaat atgatgattt tataaaaagt tatgaggaaa gtaagactac tgggcttaga
     2521 ataaatactt taaaaattga caagaaaaaa ttatttgatt tggagttgtt tgatttgaat
     2581 caaataccat gggcagaaga aggtttttat tatgatgata aaattgacag acctggtaga
     2641 aatccactgc atgaggctgg agcatactat ttgcaagagc cttctgcaat gagtgtaata
     2701 ccaaaggcag atattaaaga gggtgaaaaa gttctcgata tgtgtgctgc tcctggtgga
     2761 aaatctacat atatactatc taagctaaac gatacaggtt tattggtttc taatgaaatt
     2821 aatgctagta gaattaaggc tctaggggaa aatttagagc gatttggagc gagaaattgt
     2881 attataacaa acaccgattc taatagctta agaaagacgt ttaatgggta ttttgataag
     2941 gttattatag atgcaccttg ttctgggcaa ggtatgttta ggaaggatga ggttgccata
     3001 tcagattgga gttatgcaaa ggtagtagaa tgtcaatcca tccaaaaaga gattataaga
     3061 gatggatata aaatgttaaa gaaggatggc attttaattt actcaacttg tactttttca
     3121 agggaggaaa atgagcatgt tataaatgag tttatcagtg aatatccaca tgcagaactt
     3181 attgaaatgg aaagattatg gcctcataag ataaagggag aaggtcattt tgttgccaaa
     3241 ataaaaaaat tagaagaaga agaatgtaat gtcaaagaat taaaaataaa aaatttagat
     3301 aaagaaataa aggattatag ggagtttgaa aagaaatttt taaaggttga tttttatagt
     3361 aataaaaaaa ataaatttta tttaagagga gaaaatttgt acctacttcc tgaaatatat
     3421 ccagatacga aaaaactaaa agtattgaga tatggtttgc atttaggggt tttaaagaag
     3481 aatagatttg agccttctca tgcactatct cattacttaa aagttgaaga tgtaaaaaat
     3541 gttgaaaact tcagtgtaca gagtgaatca attcttaaat atttaaaagg ggatgttgta
     3601 aattctaatg atagtagagg atgggttttg gtttcggttg aaggaatacc tttaggttgg
     3661 ggaaaagaat cttctggtgt aattaagaat cattatccta aaggtcttag aaaagtattt
     3721 taaactatta gaaaaaagaa gtataatatt tatattgtag gtttatggta gattattttg
     3781 ctgtagattg acttaatatt taacacagag gagacgattt tagtgggtga agcagttaaa
     3841 aaagaagttg tagaatggat aaaagtgatt gtcatagctc ttgttttggc atttgcaata
     3901 actcgtttta tagtgccaac aatagtcaaa ggagaatcaa tgtatcctac attagttgaa
     3961 cgtgattatt tgatagttaa cagaattgcg tacaaggtag gagagccaaa atacaaagat
     4021 ataatagtat tcaaaaccga cttaacagag gaaaatggaa agaaaaaaga tttagtaaaa
     4081 agagttatcg gggttcctgg tgaccatgta aaaatacaag actccaaggt atatgtaaat
     4141 gataagttgt tagatgagac ttcctatata cataataatc gtactgatgg agatattgat
     4201 atcgtagttc cagaaggaaa attatttgca atgggagata atagagaaaa aagtttagat
     4261 agtagatacg atgaggttgg attggtcgac gagcatacca ttttaggaaa ggttctagtc
     4321 agattgtatc cattttctaa gataggaact attgactaaa catataaaat ttggagcaat
     4381 cgctgattag ctgaaatcac cagaccatac acaatagttg tctatataaa aaagacaaca
     4441 ccttatttag tagacttatc taaaagatag tgtttaagag acattatcaa taaagataat
     4501 ataactataa aggagaattt gtgaatgaat gaaactatta aagaagagat tgtagagtgg
     4561 ataaaaataa ttattactgc actttttttt gcatttatta taactcgttt tataaaacca
     4621 acattagtaa atggagaatc aatgtaccca acacttaaat cacatgatta tttggtagca
     4681 aacaggatga catataagtt atcagaacca aaatgtggag atataatgat atttaagact
     4741 gatttattac aagagaatgg aaggaaaaaa gagcttgtaa aaagggttat aggtgttcct
     4801 ggtgaccatc taaaaattaa ggattctaag gtttatataa atggtaagtt attaaatgaa
     4861 gtttcatata tacatgataa ttatactgaa ggcgatattg atatggtgat tcctaaggga
     4921 aaagtatttg cgatgggaga caatagagaa gttagtttag acagtagata taaagaagtg
     4981 ggattagtag atgaagaaaa tattaaagga aaagttattt taagagtatt tccttttaca
     5041 gatataggta tttttgagta ggtgatttgt atggcagttg gtatagcgtc cttattgttt
     5101 aatattgagg aggctttaaa catttgtgag agtataaagc aaataactca tttagagatt
     5161 ggaattgaca atatatctga atgtagtgag ttatgtaaat ataaagagag aatttctaag
     5221 ttaggattat ctatagggat acatttgcct atggaattaa atacttgcga aaacatagag
     5281 tatatacgaa attcatggat aaattttatt gagaagatag aatttgaact aaaaggattt
     5341 gatttaaggt attttaacct tcatttggga tatgttatga caaatagagt tagaaagaat
     5401 agagacaaat atttaggaaa tagtgtggat tttttagata aattaaatac aaattcatat
     5461 gtatgtatag agaatactta ttcaaaaggt ggggattttt caaatattgg aaatatatct
     5521 tatgattttg aatatatatt taagaggatt aaaaattcta agatttgttt ttgttacgat
     5581 actggacact gtttaattga tgaggatgct tatgtaaaga acttaaagga taaaataaga
     5641 ctgatacact taagtgataa tgatggtatc aatgatacac atgttggtat aggaagagga
     5701 attttatctg aagaggggat taaagagatc ttaacattag atgcagaata tttagtatta
     5761 gaaataaatt acgaagacat tgaagatact ataagtaaat tgaataatat tgtaggagag
     5821 ggttaaatac ctctctttat cttgttgata tgcctcatta attaaaattt atattcatca
     5881 aaaggaagga gatgttgaag tgaaaaaaat aaacttaaaa atagaaggaa aagataagga
     5941 atattcatta gaagaaaatt cccctggaat cagattggga gatatagcaa aagaattttg
     6001 tgatgagcat aagggttata taacacttgc agttgtagac aataaactaa aagagctaaa
     6061 ttgtagagtt aagaaggatt gtgagataaa ttttttagat actactaatg aagatggaga
     6121 gagagtttac tttagagtca tgtcatttat atttgtaatg gcatgtagag aaatcttttg
     6181 ggatagcaga gttacaatag aacattcact atcagatggg ctatattgtg aagttcatat
     6241 agatagaaag cttaaagaag cagatgttga aaatataaaa aacaagatga aagagatagt
     6301 aaacaacgat tatgttatag aaaaaattga agttacaaga aatgaagcta tttctatctt
     6361 tgaaaataat gaaatgtatg aaaaggcaga gcttttgaaa tacaaagagt atgatagtgc
     6421 taaagtatat aagtgtagaa actatataga ccatttttat ggttatatgt tgccatcaac
     6481 tggttatata aaatcatttg atattaagct ttataatgga ggcgttataa ttttaggacc
     6541 tagtgaagaa gataagactc ttcctatgaa atttgtacct caacctaagc tatcaagtgt
     6601 atattatgaa gcagaagaat ggtcaagact tatgggaatt gacaaggtag tatctcttaa
     6661 taaaataata gaaaacaatg aatatggaga tataataagg acatttgaag cattgcatga
     6721 aaagaagtta tcccaaatag cggatatgat aaaggatggc aataagagag tagttttaat
     6781 agcagctcca tcttcatctg gaaaaacaag ttttgctcac agattatcaa tacatcttag
     6841 agtaaataat ttaaatccta tttcaatttc tttagatgat tattttatag atagaaaaca
     6901 tactccttta gatgaatatg gaaattatga ttttgaatca atttatgcaa tagatttaga
     6961 gaagtttaac ttagacttaa agaaactttt agctggtgaa gaaattgatg atataagatt
     7021 caattttaaa gaaggtaaga gagaatacac tggtaaaaag ataaagatag attcaaatca
     7081 gccaattata ttagaaggta tacatgggct aaatcctatt ttaacatcat ctataccaga
     7141 tgaagataaa tttaagatat acataagtgc ccttactcaa ataaatttgg atgaccataa
     7201 tcgaatccct actgctgatt tgagaatgat aagaagaatt gttagagact ataattttag
     7261 aggatatagt gctgataata ctattttaca atgggcatca gttagaagag gagaaaagaa
     7321 gaatatattc ccgtaccaag aggaggcaga tgctatattt aactctgctt gtgtatatga
     7381 attggcagtt ttaaaacgat ttgcgaaacc tttgttggaa gagataaagg aagataatcc
     7441 tgcacatatt gaagctacta gattactaaa gtttttgcag tattttgttg aattggacga
     7501 tacttctgac ataccaggta tttcaattct tagggaattt attggaggaa gtaaaatagt
     7561 tgattaatgt gtgtattata gattgtttta tgaagattaa atggcatagc aagtagtgtt
     7621 attggtttat gttaagtata ttaagtgtaa agtggagaat taaattgata cagattttaa
     7681 agtttgagtt gatatataaa aaggcttgtt ttatactttt gtatgaagca agctttttat
     7741 tttaaatttt acttttttgt ttaatatttt gttaatttat gtgattattt tttaaaagag
     7801 taaaagagta aaagagtaaa agagtaaaag agtaaaagag taaaagagta aaaggtgttg
     7861 ggttagaaat ttttggtgtt ataaaaattt aaattactgg attattagat tgctggattg
     7921 ctaaattact aggttgttaa attattgaat tattaggttg ttgaattac
//
LOCUS       DAYAKB010000125         7743 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.126, whole genome shotgun sequence.
ACCESSION   DAYAKB010000125 DAYAKB010000000
VERSION     DAYAKB010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.126"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            90..164
                     /locus_tag="ACGI3L_003492"
     tRNA            90..164
                     /locus_tag="ACGI3L_003492"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:122..124,aa:Gly,seq:gcc)
     gene            189..265
                     /locus_tag="ACGI3L_003493"
     tRNA            189..265
                     /locus_tag="ACGI3L_003493"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:223..225,aa:Arg,seq:tct)
     gene            275..350
                     /locus_tag="ACGI3L_003494"
     tRNA            275..350
                     /locus_tag="ACGI3L_003494"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:308..310,aa:Gln,seq:ttg)
     gene            359..434
                     /locus_tag="ACGI3L_003495"
     tRNA            359..434
                     /locus_tag="ACGI3L_003495"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Lys,seq:ttt)
     gene            437..525
                     /locus_tag="ACGI3L_003496"
     tRNA            437..525
                     /locus_tag="ACGI3L_003496"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:471..473,aa:Ser,seq:tga)
     gene            529..604
                     /locus_tag="ACGI3L_003497"
     tRNA            529..604
                     /locus_tag="ACGI3L_003497"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Phe,seq:gaa)
     gene            611..684
                     /locus_tag="ACGI3L_003498"
     tRNA            611..684
                     /locus_tag="ACGI3L_003498"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Met,seq:cat)
     gene            699..775
                     /locus_tag="ACGI3L_003499"
     tRNA            699..775
                     /locus_tag="ACGI3L_003499"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:733..735,aa:Ile,seq:cat)
     gene            793..869
                     /locus_tag="ACGI3L_003500"
     tRNA            793..869
                     /locus_tag="ACGI3L_003500"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:His,seq:gtg)
     gene            878..953
                     /locus_tag="ACGI3L_003501"
     tRNA            878..953
                     /locus_tag="ACGI3L_003501"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:911..913,aa:Lys,seq:ttt)
     gene            961..1034
                     /locus_tag="ACGI3L_003502"
     tRNA            961..1034
                     /locus_tag="ACGI3L_003502"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:993..995,aa:Cys,seq:gca)
     gene            1042..1118
                     /locus_tag="ACGI3L_003503"
     tRNA            1042..1118
                     /locus_tag="ACGI3L_003503"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1076..1078,aa:Arg,seq:acg)
     gene            1131..1206
                     /locus_tag="ACGI3L_003504"
     tRNA            1131..1206
                     /locus_tag="ACGI3L_003504"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1164..1166,aa:Val,seq:tac)
     gene            1282..1695
                     /locus_tag="ACGI3L_003505"
     CDS             1282..1695
                     /locus_tag="ACGI3L_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199184.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2004..5435
                     /locus_tag="ACGI3L_003506"
     CDS             2004..5435
                     /locus_tag="ACGI3L_003506"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFG9199185.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTRESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5677..7605
                     /locus_tag="ACGI3L_003507"
     CDS             5677..7605
                     /locus_tag="ACGI3L_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFG9199186.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
BASE COUNT         3061 a          961 c         1539 g         2182 t
ORIGIN      
        1 gcagacgcac tagacttagg atctagcgcc attggcgtgg gggttcgact cccttcatcc
       61 gcaccatttt tatttaattt aataaacgag cgggaatagt tcagtggtag agcgcaacct
      121 tgccaaggtt gaagtcgcga gttcgaatct cgtttcccgc tccaaatttt atgtttatgt
      181 tgtaatgtgg gtgcatagct cagctggata gagcaacgcc cttctaaggc gtgtgtccgg
      241 ggttcgaatc cctgtgcgct caccacatat atattgggga ttagccaagt cggtaaggca
      301 catgactttg actcatgtat gcgtaggttc gagtcctgca tccccagcca aacagtatgg
      361 tctattagct cagtcggtag agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg
      421 cggatagatc accaatggag aggtgtccga gtggtttaag gagctggtct tgaaaaccag
      481 tgacttcgaa aggggccgtg ggttcgaatc ccaccctctc cgccaaatgc ccagatagct
      541 cagtcggtag agcaggggac tgaaaatccc cgtgtcggtg gttcgattcc gcctctgggc
      601 accaaaatgt ggcggtatag cttagttggc tagagcgttc ggttcatacc cgaaaggtca
      661 taggttcgac tcctattacc gctactgaaa tttaatgtgg gccattagct cagttggtta
      721 gagcgcccgg ctcataaccg gtaggtctgg ggttcgagtc cctgatggcc caccacatta
      781 aattaactta tggtgggtat agctcagttg gttagagcgc cagattgtgg ctctggaggt
      841 cgtgagttcg actctcatta tccaccccaa cttatatggt ctattagctc agtcggtaga
      901 gcacctgact tttaatcagg gtgtcccgcg ttcgagtcgc ggatagatca ccaaaaaggc
      961 ggcgacatag ccaagtggta aggcagtgga ctgcaactcc ttgatcccca gttcgaatct
     1021 gggtgtcgcc tccaataaaa tgcgctcata gctcaactgg atagagtgtc tgactacgaa
     1081 tcagaaggtt aggggttcga gtccctttgg gcgcaccata tgaatagcga gggattatag
     1141 ctcagctggg agagcacctg ccttacaagc agggggtcac aggttcgagc cctgttaatc
     1201 ccaccagtgc aaacctctag taaaactact agaggtttta tttttgattg aaaaagtttt
     1261 tatatttagg aggtaaaaaa tttgtatata gtaataggaa atgaaatagt tgatagtgaa
     1321 gaacttaaaa taattataga taaaaatagt gaatttaaag ttgaaaaaga tttaagtaaa
     1381 agcacaaaaa gagaagatgt aatagcatat cagttaagta tagatttaaa ttacctagat
     1441 tctcttataa atgagcaatg taatttagcc agtctatctg atgaagagaa atttgatgaa
     1501 tatatgactt tgtctgatga acttgcactg gatttagaag agttaatgcc aaaatataca
     1561 ataataaatg ctagagcata taaattagac gaggtagatg gaattgtaaa aataatacta
     1621 gctgtagcgt atgcagattt agggcacttg aaactttctg atgtagtaaa gaggctatct
     1681 agacaagtag attaggatat gaatatgaac tatattaaaa aaatgtataa aatcttacgt
     1741 aaagatgaaa ataattatgt aaacatagaa aaaaacagta taaaatcaag tcaattgtag
     1801 aaattttcac ataaattcat ctgaaattct ataaaaaatg ccttaatttt aatgaggtaa
     1861 atcgagttta cacagtctaa aaattactta tatttataaa tttatcttat taattaagga
     1921 actttcttaa acatcttcaa aaataaagta ttttagtcta taatctttaa tattacacaa
     1981 acaataaagg agaagaatag agtatgctta aaaagtttaa taaaatacta gtggctaata
     2041 gaggcgaaat agctataaga atatttagag cctgttcaga attggggata aaaagtgttg
     2101 gtatatacag taaggaagat aagtatggat tgtttagaac aaaagcggat gaatcatatt
     2161 tgataggaga aggtaaaggg ccaatagatg catatttaga tatggatgga ataatagacc
     2221 tagcaaagag aaaaaaagtt gatgctatac atccaggata tggttttcta gcggagaatg
     2281 cagaatttgc tcgtaaatgt gaagagaatg gaattacttt tataggacca tcatctaagg
     2341 taatgaatat gatgggggat aagattaact ctaaaaaaat cgcaaaagaa gttaatgttc
     2401 aaactatacc aggagtagaa aaagcaataa gaagtactga agaagcaaag gaagttgcaa
     2461 acaaaatagg atatcctgtt atgataaaag catctaatgg cggtggcggt agaggtatga
     2521 gaattgtaca tcgcgaagaa gacttagagc ttgaatatga aactgcttgt agtgaatcaa
     2581 gaaaagcttt tggagaagat attatattta tagaaaaata tatagctgat ccaaaacata
     2641 tagaagttca aatattaggt gataattatg gaaatatagt tcacttatat gaaagagatt
     2701 gttcagttca aagaagacat caaaaaataa tagaatatgc accagctttt tcattagatg
     2761 ataaagtaag aaaagagata tgtgaagatg cagttaagtt atcaaaacat gtgggttatt
     2821 ctaatgcggg aacattagaa tttttagtag atgcaaatgg tgggcattat tttatagaga
     2881 tgaacacaag agtacaggtt gaacatactg taacagagat ggttacagga atagatatag
     2941 ttcaaagtca aatactaata gcccaaggtt acagcttaga tagtgaagaa attaatataa
     3001 aatcacaaga tgatgtggaa ataagaggtt actctatcca atgtagaata actacagaag
     3061 accctaagaa taaattcatg cctgatacag gtaaaattca agtttataga actggttcag
     3121 gatttggtat aagactagat ggaggaaatg gatttacagg ggcaaacata agtcctcatt
     3181 atgatagttt attggttaag acaatatctt gggatagaac attccaagga gcaataaata
     3241 aaactataag atctataaaa gaacttagag ttagaggtgt taaaactaat gtaggattcc
     3301 tagttaatgt tttaaataat cctatattct caaatggtaa atgtagtact aagtttatag
     3361 atgaaaatcc agatttattt gaaataacag aaagtaaaga cagaggaaca aaattacttc
     3421 aatttatagg agatgtaatt gtaaatgata atgcttgtaa agaaaaacca ttatttgatg
     3481 cattacatga cccaagaatg gataaggatg gttcaaaatc agaaggaagt aaaatacttt
     3541 tcgataagtt aggtaaatct gcatatatag aaaagataaa aaatgataag aaattactat
     3601 taacagatac aacaatgaga gatgcacatc aatcattatt agcaacaaga ataagaacat
     3661 atgacttatt aaaagctgct aagccaacag aaaaatatca aaaggattta ttctcacttg
     3721 aaatgtgggg aggagctact tatgatgttg catatagatt tttaaaagaa tctccttggc
     3781 gtagattaca aaagctaaga gaagaaatac caagcataat gttccaaatg ttgcttagag
     3841 catcaaatgg agttggatat aaaaactatc cagataatgt aatagaagaa tttacaagag
     3901 aatctgctag acaaggtata gatgtattta gaatatttga ttcattaaac tgggttgaaa
     3961 atatgaaacc atctattaat acagctttag aaactggaaa aattgttgaa gcaactatgt
     4021 gttatacagg tgatatacta gataagacta aaactaaata caatctagaa tattatatta
     4081 aaatggcaca agaattagaa agcttgggag cagatataat agcaataaaa gatatgtcag
     4141 gtcttcttaa accatattca gcttacacat tagttaaaga gttaaagaaa aatgtaaaag
     4201 caccaataca tttacacact catgatacaa gtggaaatgg tgtagcaact tgtttaatgg
     4261 cgtcagaagc tggagtagac ataattgatg ctgcattaga atctatggca ggacttacaa
     4321 gtcagccatc acttaatgct atagtagagg cacttaagaa tacagagaga gatacaggaa
     4381 tagatttatt tggatatgat gagttaggaa aatattataa ggatttaaga aaagtttata
     4441 ataaatttga aagtgattta actaattctt gtgcagaaat atataatttt gaaataccag
     4501 gaggccaata tacaaactta aaacctcaag ctgatagttt aggattagtt aatagatttg
     4561 atgaagttaa agaaaaatat aaagaagcta atgaagttgt aggagatata ataaaagtaa
     4621 ctccatcttc aaaagttgta ggagacttag ctatctttat gactaaaaat aaattagata
     4681 aagacaatat aatagaagaa ggtaaaaatt tatcattccc agattctgtt gtggattact
     4741 gtaaaggtat gattggtcaa ccagaaggtg gaataccaaa agatttacaa gaggtagttc
     4801 taaaaggtga agaagctata acagtaagac caggttcatt attaccagca gaagattttg
     4861 atgaaatagc taaatatcta aatgaaaagt atgatataaa tgctaatata agaaatgtta
     4921 taagttatgc tttatatcca aaagtatatg aagattatat caaacatcta caacattata
     4981 atgatatatc taaacttgaa agtgatgtat tcttctatgg attaaataaa aatgaagaat
     5041 gtgaagtaga aatagaagaa ggtaaggtat taacaataag attagttgaa attggtgaag
     5101 ttaaggaaaa tggatttaga actataggat ttgagttaaa tggaatggtt agagaagtag
     5161 aaataaaaga taagaatttc tctggaaaaa ttaataatgt tgaaaaagct gatatgaatg
     5221 accctcttca aattggagca agcataccag gaaaagttat aaaaataatg gttaaagaag
     5281 aagatgaagt aaaagcaaat caaccattaa tcgttataga ggctatgaag atggaaacta
     5341 taatagttgc taagactgat ggagtaatta agtcaatcaa agtaaaagaa gatgatatgg
     5401 ttgaagataa acaattatta atgataatga agtaatttaa ttaaaataaa ttaaaaagca
     5461 ctctgaaatg tttaataaaa aatgttttag agtgttttta tttattttaa ttaaatattt
     5521 gttaaaaaaa agaggacaat tacctccaga tgtagaaata aagctagtaa ggaaaatgtt
     5581 atctaaaaat tctaaatata gtaaatattt tccataatat ttcttaggaa ataacagcaa
     5641 agataaaata cataaattta aaaggtgggt gcttatatga aggtttatga tagtaaaatg
     5701 ttgagaaatg tagcggtatt aggacatagc ggatgtggaa aaacaaatct aatcgaaact
     5761 atagcttaca cagcaaacac taataagata cctaaattaa cagacaaggt aaatatgact
     5821 tatagcatgg gattaatacc tatagagtat aatgattata agtttaactt attggatacc
     5881 ccaggatatt ttgactttag cggagacgtt gtgtcatctc ttagagcaag tgatgcagca
     5941 ataatagtaa tagatgcaac agcgcctatt caagttggta cagagaaatc attagaacta
     6001 actgagagta ttcctaagat aatgtttata aataaaatag ataatgaaaa ggcaagatac
     6061 aaagatgcaa tagcaatgtt aagagaaaaa tacaataata agatagttcc tatgataagt
     6121 cctatataca aagataaaaa ctttgtaaag ttacataatg tttttgaaaa catagatgat
     6181 ttagaaggtg aatttaagga acaagctatg agtgttaaag aagcattaat ggaacttata
     6241 gcagaaactg atgaccaaat attagataaa tattttaatg gagaagaact aactacagaa
     6301 gagatacaaa aaggtattat tataggtata caaagaggtg atattatacc tgtaatatgt
     6361 ggttcaacta taaataatat aggcacaaag gaaatattag atacaatatc aagttattta
     6421 gaacctatct ttacagagga aagcaaacca tttaggggat tagtatttaa aactatggtt
     6481 gacccatttg ttggaaagat gtcatatata aaaattactg agggtgtact ttctaaggat
     6541 aaagatgttt ttaatataaa taaaaatgta aaagaaaaaa tagctaatat atatacattg
     6601 agaaatagtg aattagtaga aatagaaaaa gctaaagctg gtgatatagt agttataact
     6661 aaagttaatt ctctaaaaac aggagacact atatctgcag ataaagatgc agaagcttta
     6721 gaaaagatag attttcctaa accacaaata tattatgcag taactcctaa gaataaaggt
     6781 gatgaagaaa aagtagcatc tgtattaaat aaactagtag aagaggaccc tacattacat
     6841 tggtatagaa atacagagac aaaacaagca cttttaggag gtcaaggaga acttcatata
     6901 aaaacaatta aaaataaaat gaaagataag tttggtgttg atgttgaatt gaatgacctt
     6961 aaagttcctt atagagaaac tataaaagga acagctgatg tacaaggaaa acataaaaag
     7021 caatcaggtg gtcatggtca atatggagac gtaaaaataa gatttgaaag atgtgaatct
     7081 gattttgaat ttacagaaga aatatttggt ggttctgtac caaaacaata tataccagca
     7141 gttgaaaaag gtttaaaaga ctctatgcaa aaaggtatat tagcaggata tcctgttaca
     7201 aacataaaag ctacgcttta tgatggttca taccatgatg tagactcttc tgaaatggcc
     7261 tttaaaatgg cagcaagtgc agcctttaaa aaaggtatgg aagaagcaca cccaatacta
     7321 ctagaaccta taatgaaact taagataact gttccagaag aatatatggg agatgtcatg
     7381 ggtgatataa ataagagaag aggaaaaata tttggaatgg aaccagatga caaagggaaa
     7441 caaataatat ttgcagaagc tccacaagca gagacattta aatatgcaat agatttaaga
     7501 gcaatgacac aaggtagagg atactttgaa atggaattag agagatatgg agaggttcca
     7561 tcacagtttg cagaaaaaat aattgggtta gctactgcaa agtaatgaac aaaataaata
     7621 gaaaaataat taatatatat tattaaaaat atttttaggg ttttaactag gtataggttt
     7681 atgttaggta aacttatacc tagtttttat acatttttga tgaataaaaa aatatataat
     7741 act
//
LOCUS       DAYAKB010000126         7737 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.127, whole genome shotgun sequence.
ACCESSION   DAYAKB010000126 DAYAKB010000000
VERSION     DAYAKB010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.127"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            207..1481
                     /locus_tag="ACGI3L_003508"
     CDS             207..1481
                     /locus_tag="ACGI3L_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster-binding protein"
                     /protein_id="HFG9199187.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(1642..4683)
                     /locus_tag="ACGI3L_003509"
     CDS             complement(1642..4683)
                     /locus_tag="ACGI3L_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HFG9199188.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            4889..5188
                     /locus_tag="ACGI3L_003510"
     CDS             4889..5188
                     /locus_tag="ACGI3L_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFG9199189.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(5427..7655)
                     /locus_tag="ACGI3L_003511"
     CDS             complement(5427..7655)
                     /locus_tag="ACGI3L_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFG9199190.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT         2689 a         1103 c         1084 g         2861 t
ORIGIN      
        1 cttaactata taaaatatta ttaaaatcat ttaagtggta taaaatatta ttatatcact
       61 taaataattt tttatttata taagaaatct aataataaat tactagaggt atttaactat
      121 ttagaaagaa ttggtattat ataaagtaag agaatatata ataagaaaga atatttgatt
      181 ttattggaaa acaaaagaaa aagaaggtga ttactatttc tcatataact gcgaagaata
      241 tgtataaaag tttagaggaa agaataaaca agtttccaca aggtgctcca ccatctgata
      301 cattatacaa aatactaaat gtactatata cagaacaaga ggcgaagtta gttgctcagc
      361 ttccaataaa gcctttcaga gtaaaaacag cagctaaaat ttggagtgta agtgaaagtg
      421 aagcatatag agtattggat aaacttgcta gtaaggctct gatactagat atagaagata
      481 ataaagggaa gaaatatata atgcctcctc caatggctgg tttttttgag tttgccatga
      541 tgagaacgag acacgatata gaccaaaaac ttttggcaga gctttactat caatatatga
      601 atgtagaaga agattttatc aaagatttat tttattcaac agaaacgaag cttggaagag
      661 tatacgttca agaggaagtt ttaactaatg ataatgaggt tagtatttta gattatgaaa
      721 gggctactca tataattgat gaatcaactc atataggtat aagtatgtgt tactgtagac
      781 atagaatgca acatgttgga aaagcttgtg atgctcctat ggatatatgt atgacgtttg
      841 acaatgtagc aaattcttta ataaataata aatttgcaag acgtgtggat aaaatagaat
      901 gtaaagagct acttcatcaa gcatatgaac ataacttagt tcaatgtgga gaaaatgtta
      961 ggaaaggggt tacgtttata tgtaattgct gtggatgttg ctgtgaagca atggtagcag
     1021 ctaaaagatt tggaaatctt catccagtac agacaacaag ttttatacca aatataaacc
     1081 atgaaaattg tgtaaagtgt ggtaaatgta taactgcatg tccaatagat gcgataagca
     1141 aggttaagga agatggtaaa gaatatataa aaattgatga ggatagatgt ttaggttgtg
     1201 gagtttgtgt tagaaattgc cataaaaata gcattatgtt attaaagaga gatgaaaaaa
     1261 taataactcc agcaaattca gtacatagag cagttcttat ggcaattgaa aaagggcagt
     1321 tacaaaattt aatttttgat aataatgctc tggctagtca tagagctatg ggagctatac
     1381 tgtcagctat attaaagctt gaaccagcta aaaagatttt agccagtaaa caattaaagt
     1441 cagtatattt agataaattg ttaagtatga atgataaata gaaactaact taaaaaaggc
     1501 aaagttttag acttatctat atcttaataa acttatcatt taatatttaa atttaatttt
     1561 tacacatata aaacttataa cttaaataaa aaaaggctat attcaattaa tattacttga
     1621 atacagcctt ttttagttat gttaagctat ttcttttatt tgcttaaatg agttttcatt
     1681 tccatttcca ccaatttgtg ttacagattt aaatctcata gttttaaata gttctttttg
     1741 attataatct agtgagtttc ctactagcat tacaggagat ttagtttttc cagccaaaac
     1801 tccaacagat aatccgtcta ttaaatcatc ttgtttattc attccatttt tagcaacata
     1861 taaattgtct atcttagaat ccttgtaaaa ttcttttatt acttttgcat tagtttcatt
     1921 tctagtgcta cctgatattc tctgtggatt ttgaagttta ctttctatat ttttagaaac
     1981 tgtatattct ccaccgatta cataagattt atcaatcttt ttgtttttaa acaagttatt
     2041 tatttcagtt atattactat tttcattagt aagtattata ggcatatcat tttgagctga
     2101 tacagctcca atgcttactg catcggctaa tcctttttcg ccattaacta ctgaaatctt
     2161 tgatatattg ctaatattgt tcaattcttt agcaatgttc atagaagttt gatatctatc
     2221 acttcctgaa attctagata cagagatatt gtttgatttt atagtatcta aagatttttc
     2281 atttatagaa gcttctccac caactacata tacattttta acttttaatc tctttaattc
     2341 agccaaagtt ttttcattta tttgagagct tccagtcaat aatataggag cgtttttctt
     2401 gtatgcaaat ggtgttgcag ccaaagcatc tgcaattgct gaatcgttta ttaaaactgc
     2461 attttcagca ttttcccaac ctgcttgact tatcttaata gaagtttcat atctatcagt
     2521 tcctgtaagt gcacttgcat ttacttcatc ttgatatgta acctcaaatc tagcatttgg
     2581 acttcctaag aaaacaatta cgcctccttt tggcaatcta actctattgt tctttgtaac
     2641 taaagaatag tttacaggaa cacctttatc atcataaaca gcaaaagctg aattttgagg
     2701 aagattaact tctatttttt tatttgcgat atcgtcacca atcttatacc attttgcata
     2761 accattggat tctagttcac aagtaaaaga tttttctgct ggcaaattag ttatagaatc
     2821 ttcactaaca tacgttagtg ttccaaaaga taaatactct gtaccatttt ctttatgaag
     2881 tttaatgtcg gataaatcac gacctattac accaggtatt tctataaaag catttgagtt
     2941 attctcatcc attattttag tgttaactat ataacctgga gtttcatcag aaagagcaag
     3001 agttgccttc acagaaccaa acatatagct ttgagaagta tatttttcat ctactagata
     3061 gtaatcttta ccatttcttt ttttccatgc ttcttttaca ctatttgata tattgttgtc
     3121 atctatcttt tgagctacat agtataaact tgctgtctga cctaatccag ggacatcatc
     3181 ataagagctc atatttaaat atgtgatatt gtttttttct tttacaaatt ttagacagct
     3241 gttacctttt tcagatacaa atctatcttg acctatgtat acgtatttat cttcaggtcc
     3301 attttctata taaggagaag atactgttaa agtaccatta tcattaacat ctacttttat
     3361 catatttgaa gaagcataaa gaccactatt ttcttttaga gagctaggca ttttaacttg
     3421 ttgtggttta ctaaatgttt tatcaggttt tatttcttta attttacctt tttcttttaa
     3481 tgcagatagt aagatttctt gtccaattat ttcattaagt tgactacttc caccagaaga
     3541 aagaactgca actgccatat tttcatctgg aagaactata agattactgt ggaataataa
     3601 agagtctcca ccttttgtaa gagcttttaa attatactga ttaaatggat aagtgttgac
     3661 acaatcccac cctaaaccat atccaagtat agagtcttct ccttcaggcc atagaccatt
     3721 taaatattct ttgttttcca tagcttttac tgaagcagga gaaagaatac catttgaatt
     3781 tttcataaat gtttgtgcaa atgtacatag attttctgca cttgaatata aaccacctgc
     3841 acctatagca ttaaggttat cttgcggaac tgcatcttcc caataaggca cgtatgcttt
     3901 tgctagtttt gaactatcaa aactattttc tgtagttttt gtattttgta agttaagtgg
     3961 attatttatg tatttatcaa gaaaattagt aaatgacata ccagatactc tttctactaa
     4021 aatttcagct aaagtaaatc catcattaca ataaacggaa aaagctcctg gtttagcttt
     4081 taatctttgt ttttgtaatt cttttaagaa attatcatga ccataagaat cattgtctgc
     4141 taataaaata gtgtttttaa aactacttcc catcaaccct gatgaatgat ttaataacat
     4201 tcttggagtg atttccttgt atctatcatc agccatttta aattcaggta tatactttac
     4261 aacaggagta tctaaattta attttccatc atcaaccaac ttcataacag ctgttgtagt
     4321 aaacatttta ctgatagatg cgatactata catattatcc ttatttaagt ttttgttatc
     4381 ctgtttgctg taaactccac cattaccaga aatctcaatt ttgccattat caatcaaagc
     4441 atattgagca cttacagcac catactttga tagcaaagtt tggattttct ctttagcaag
     4501 agctttagtt tttgtgtaag attccgcgtt tttactataa tcatgtaatt ctatatcaga
     4561 actttgatat ttttcggaat tatcttttgt attatcagca aaagtaatat ttggagcagc
     4621 agtaaataac atactcaata ctaatgtact agataataat ttagagagcc tttgcttaaa
     4681 catattacat tacctctttc cctttttaat aatttataat tagcataaca ttcttaatta
     4741 ttttaatcaa cagattatta tcaataaaaa aagcttttat aagtatagct ttttatataa
     4801 cagagaaaaa tataaaaata atatttgttg ttgtataaag aataaagggt ataggtaata
     4861 tataaataaa atggaggaat tttagacaat gtataagaat ataaataaaa agcaacttaa
     4921 agaaatgatg aaaaatgaaa aggatgtttt attattagat gtaagaacta aagatgaatt
     4981 taaggaatat aaaatagaaa atgctataaa tatatcttta caagagttaa tcaataatat
     5041 agatgaaatt tacgattata aagataagaa agtagtagtt tattgcagaa gtggtcatag
     5101 aagtgttact gcatgtaatt tgttagctga agaaggtttt gagcatttat ataatttaaa
     5161 ttcaggaata attgattata tgagttaaat aatgtaagtt atacattaaa tactatgtat
     5221 agctctgctt attaagtagg aatatatcta aatatttata agataaattt aggaaagaac
     5281 gaattttttc gtttttttct atgacagttt ttgtagtaaa tattagtttt taagttggaa
     5341 aaaggtagta gctttttagc tactaccttt taatatgaac ttagaatatt attaaaaaaa
     5401 atatatttaa agacagaatt aattttttaa tgaccagtta aattactatc gccgaattta
     5461 tcattaaatg gttttataac tctatttata ggtcctttta gaagtacatt taaacaaata
     5521 gacagaatca taaatagtaa tagaactagt atatctttag ttagatttgg agcatatata
     5581 ccaccaactg cttcccttgt agcacctatt gcataggtaa atggcattat agggtttatt
     5641 ctttggaaga atgtaggtgt aacctgtata gggaatgtac caccagaaga accaatctga
     5701 acgactaata gtactattgc aattgctttt cctacatttc caaatacaga aactaaagaa
     5761 tacactataa agttaaatac catactagta aacataagca gaactatcaa taaaattgga
     5821 tgttttgctg ttactcctaa caataatata tctccagttc ctattataaa accttggaca
     5881 agagctatac ttaaaaaagt aaggcctctt ccaaagtaaa tttcataagg tttatagttt
     5941 ccatgtacag atgtagacaa tagtgctgaa ataagtaata taccaaccca tgtagaaaga
     6001 acactataaa atggtgtcat tgcagaacca taattttcaa ttggatataa tttctctgtt
     6061 ttcacctcaa caggttcttt taagaaatta gactttgtca atatatcact ttcaagcaag
     6121 ctgactaatt ttttcatatc ttcaccatta ctaattttgc ttaaagtatc aatcaaatca
     6181 tccaacattc cttttgctaa aggaagtctt tctcttatca atgatatact ttcctgtgca
     6241 tttcctgaaa gttttagaga agtagtaagt atttcttcaa cctttggaag ttttgcttct
     6301 gccttatcta aaacagtaat tatatcattt gctactttta tactgtttgc aaatatacta
     6361 tttataggtt ttgatatttt tgagtcaaaa ttatttaaaa tatttaaatt aattcttcca
     6421 ataccatttg atagacttaa aacattattc aaagcactta tagatggttg ttgtccagat
     6481 ataactttgt ttttaatatc atttaatgtt gatatagatg aatctatttt attgctagag
     6541 tcttcaagat tatctattac atcatccaat ctattatttg atgtaagttg gtttaattta
     6601 gttaaaaagt ccaccaaagt atcgtttaaa gattgcaaat tagaaagttt ttctgataaa
     6661 ttatctatca acttaggtac atcttcactg ccactattta ctgcatcaat taaatttaat
     6721 gtaagagaag aagcagaaga tgaaaggtca accattaaat ttaagtcaga cttaataaga
     6781 ggagaaagtt cgtctaaatt atcatttgta tcctctaaga atttttttaa gtcacttgat
     6841 aatagttttg tatcattcag agtcttttta attgtaggta aatcagattt aatatcttta
     6901 actgtatcag ataattttga agtagcatca gaagctaaat caacagtctt atttatatgg
     6961 tcaaatctct tttgaaggtc aataagggaa ttttcaactt ttgtcaattt tggaagactg
     7021 tgttcaattc ctgcaccaac tccgtttgat ataccaagaa cgatttcact aactgttttt
     7081 actatagtct gattaacctg tagttgtatt gtagaagcac ctttatctgt aatctttggt
     7141 gcaactgcat ttattttttc attaacagta tagataattt cgcctttttt aacatcatct
     7201 gtaattaaag atgtcaaatc ttttgtaaaa ttttttggaa tcttaagtga tgcataataa
     7261 gtaccttttt taacaccttc aagagcagtt ttttcatcta caaactgcca acctaaactc
     7321 ttgttatctt tgagttgttc aattaattgg tctcctacat taatcttttg tcctgctatt
     7381 tcatttcctt tatcttcatt tgttactgct acaagcatat tagcagtgct tccataaggg
     7441 tcccaagatg cctttatatt gaaccaagca tacagagatg gtaaaaaagc aagacctaaa
     7501 actattacaa gtacggcata attgccacgt atatctttta ggtcactttt aaaaatttct
     7561 aatatatttt ttaaaccctt tgaaggtctt aaattcttga tattattcca gtttaaaatt
     7621 tcttttaaac tattagtttt tttcaaatgt ctcacctcct aaaatatttt gataaagaaa
     7681 aaagttagat ttataatcaa ttttaaatta tattactttt tacacaaata gtaaagt
//
LOCUS       DAYAKB010000127         7606 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.128, whole genome shotgun sequence.
ACCESSION   DAYAKB010000127 DAYAKB010000000
VERSION     DAYAKB010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7606
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.128"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(315..908)
                     /locus_tag="ACGI3L_003512"
     CDS             complement(315..908)
                     /locus_tag="ACGI3L_003512"
                     /inference="COORDINATES: protein motif:HMM:NF012861.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFG9199191.1"
                     /translation="MVGAVAGLIVLLYRILLGQAGTWLSQILKFVEGSTIKIIAWFAV
                     LAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKIKQVWWRVLPTKFIGGFLSLMGGLA
                     LGREGPSIQLGAMAGKGISRALDRGKTEEKFLLTCGASAGLSAAFHAPLAGVMFSLEE
                     VHKNFSVSVLISVMTASLTADYISANFLGMESVFQFD"
     gene            complement(1140..1676)
                     /locus_tag="ACGI3L_003513"
     CDS             complement(1140..1676)
                     /locus_tag="ACGI3L_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HFG9199192.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1749..2162)
                     /locus_tag="ACGI3L_003514"
     CDS             complement(1749..2162)
                     /locus_tag="ACGI3L_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HFG9199193.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2628..3182
                     /locus_tag="ACGI3L_003515"
     CDS             2628..3182
                     /locus_tag="ACGI3L_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HFG9199194.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEDTI
                     SGMQGTISDMQGSISSMNGTISDMQGSISSMDGTINSMQDSITDMQVEIKEVNSRLDN
                     MEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIK
                     NDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3790..3993)
                     /locus_tag="ACGI3L_003516"
     CDS             complement(3790..3993)
                     /locus_tag="ACGI3L_003516"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019846.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9199195.1"
                     /translation="MCLDAVIYMLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDI
                     VFSCIVFHHCTNVQNIFCIFWKW"
     gene            complement(4195..4728)
                     /locus_tag="ACGI3L_003517"
     CDS             complement(4195..4728)
                     /locus_tag="ACGI3L_003517"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFG9199196.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            5495..5683
                     /locus_tag="ACGI3L_003518"
     CDS             5495..5683
                     /locus_tag="ACGI3L_003518"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199197.1"
                     /translation="MPYKYFTEFCLLKATQFLKGTNELISDIAIKVVFHQIIYFSKCF
                     KEKTGYSPKVYRNIKKEI"
     gene            complement(6312..6884)
                     /locus_tag="ACGI3L_003519"
     CDS             complement(6312..6884)
                     /locus_tag="ACGI3L_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9199198.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(6946..7209)
                     /locus_tag="ACGI3L_003520"
     CDS             complement(6946..7209)
                     /locus_tag="ACGI3L_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HFG9199199.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(7209..7430)
                     /locus_tag="ACGI3L_003521"
     CDS             complement(7209..7430)
                     /locus_tag="ACGI3L_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HFG9199200.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         2642 a         1299 c          917 g         2748 t
ORIGIN      
        1 atagcttgta gtgtacttcc ctcaagagga atagtcgttg aagtttctcc tattcggagt
       61 ttacctgctg attgcccatt ttaaagtact tagggtttaa ccttatacca tctaaccaat
      121 tttttctact ttcgtaactt tcacacttag gtttatttca tccttatgtt ttagtttggt
      181 tagctttagg ggtttccagc aattcaagta gtattggata ggttctatcc tatctctaca
      241 tataggtttc cctatatgct gactatttta gctactaact catgactaaa gtcacaagtg
      301 ttcgtagcta ttttttaatc aaactggaat acagactcca ttcctaggaa attggctgaa
      361 atatagtctg ctgtcaaaga tgctgtcatc acagaaatta aaacagatac tgaaaagttt
      421 ttatggactt cttcaagtga aaacataaca cccgctagtg gtgcatgaaa ggctgctgat
      481 aatccagcac ttgccccaca ggttaacagg aatttttcct ctgtcttccc tcggtcaaga
      541 gctctagaaa tacctttacc tgccatagca ccaagctgaa tggaaggacc ttcccttccc
      601 aaagcaagac cacccatgag tgataagaat cctccaataa attttgttgg caacactcgc
      661 caccatactt gttttatttt ccctgtcatt tccccctcaa gctgagggat accacttcca
      721 gaaatcattg gctcccagtc caccaacttt gatacaatcc acgcaagtac tgcaagtact
      781 gcaaaccaag ctattatttt tattgtagaa ccttctacaa attttaaaat ttggctaagc
      841 caagtaccag cctgccctaa aagtatcctg tataaaagca caatcaaacc agccacagcc
      901 ccaaccataa gtccttcacc aatcaaaatt acctgaaagt gctctgcccg tttgataata
      961 tgagatgtat cctttttcat actattcctc cttcatccaa taattctaca caatctgaat
     1021 ctccaatgac taaagtcatg agtgtgtaca gatatttttt aatcaacaaa aatagatttt
     1081 tacttactaa atataagaaa ataattgctc aatttctcaa taaatgtgaa tttattcttt
     1141 taggtattta ttctccacag tcgtgcttct tccagcaaaa tatttattaa ttcttgcttt
     1201 ctctgtgtat agattttacg attgtcctca aactgtaatg ctaatttttg tttatgacta
     1261 tcatagagtt ttgctttgtc tgtaaaagta tttagataat ctcgaaaatt gatataatta
     1321 ttccatgcaa cactattcca ttcaacaaca tgaatatggt gagtacgagt atttttctca
     1381 aaatctccca tagcaaaaag taattgtttt ggtacatcct gacctcgaaa aacgattcca
     1441 cattgctcta acctttcgag gtataattta gcttcctcta aagaagcaac acctacaaca
     1501 atatcaataa taggctttgc gctaatactg ggaatagaag tgcttccaat gtgttgaata
     1561 tcaatagcag tcttatccca tatacttttt aataatataa tgacatcttt tgcactttta
     1621 tcccatatca tctgatgttc caataattta accataccac attttaaacc tatcactata
     1681 taccacctca atataatcca cctttatata tattacaatt ttttctatct tgataaatag
     1741 tgatttagct atttcacttt ttcttgacac tcgctacatt ccctatcatg aatagatata
     1801 attcctccac atttagaaca agtatatctc tccttctgct tttgcataaa cttctctaaa
     1861 ccgtactgct gaacaaattt actattttcc ataaggcttg cttgatatct cttgttataa
     1921 cttttttcaa gattttttat gagtttacaa ggaaaattga aacattcaaa acaataaaac
     1981 aacccttttt gacagacaca atcctttatt ttgcacttac ggcagtgttc tggctttcct
     2041 gtatcgccgt tcaaacaacc agcacatggc tttttgtgat aacaatgctt atagcaaacc
     2101 atacaattca ttccacaagg agcaaacata atcgtatcaa tactctcttt tggcattttc
     2161 ataacatttt actcctttca aaaatccaat ttgtcgaatt gttatatatt catattgtaa
     2221 cataaaaaat agctaaaaaa ttcatgcact ttcattgcca ataaattttc aaggaaatat
     2281 gaaagtttaa aactaagaat aaaaagagat aaaaaggaag ctactaatca aaatattcaa
     2341 acacaagtaa tcaatataaa taacttaagg tatatttaaa agtatatgat attaccagca
     2401 gttttaaata caaatataac cacacatgcc tcaaaaacac ttattacagt atcttagaaa
     2461 cttagacaat acataagatt cattaataaa aaagttctca atatagatat atttaaccat
     2521 gttttgaata gtagataatc atatgattaa aaattaaata tgacatagcg tttgtggaat
     2581 ataacaccta aattatgtta taataataaa gcaggagtgt gatagtgatg gatgaaaaaa
     2641 tattagagtt attacaggaa atgcaaggta atattagtaa tatgcaaggt agtatcagtg
     2701 gtatcgaagg cactattagt gatatgcaaa gcaatattaa tggtatcgaa gacactatta
     2761 gtggcatgca aggcactatt agcgatatgc aaggcagtat cagtagtatg aatggcacta
     2821 ttagcgatat gcaaggcagt atcagtagta tggatggcac tattaatagt atgcaagaca
     2881 gtattactga tatgcaagtt gaaattaaag aagtcaatag taggttagac aatatggaac
     2941 ctgatattaa agacttaaaa actggacaag ttgaaactag tagtagactt gatactattc
     3001 agagtgatgt tacagaaatt aagtcagatg taaaaattaa cagaaataca ttagatacag
     3061 tgattaaaca tacctcttca ttagtaaaag atacatcaga tattaaaaat gatttaaata
     3121 atatagagat agtcacatct aagaattcga atgatattgc taaattaaaa tcagttaaat
     3181 aatatactat agtaaaaaat acctgaaaat ttcacatact tctttaaagt tataccaaat
     3241 tttatacaga aatactgatt atccgacaac acactttact tataaataat ttattaaaaa
     3301 aatactcatt ttatcctaaa attaacacga ctaaatgagt cttgatataa taataaaaaa
     3361 taagggagat tgaacactaa aaagttgtgt atctccctta tattctataa tatagttata
     3421 taatttttca gcctaaaata aaagtccatc tttgattaaa acacatcccc ttatcactta
     3481 taaaaggata aaatcttgtt ttcatttttc catttatatc ttcttgctta agagtaataa
     3541 ttttttcttt tgatacttta agtgattggt taaatttaac caaacgacta agttttgttc
     3601 aacatctatt tttcatattt tccaatactt aatctatttt ttataaataa ttcttttatt
     3661 tctaactcac ttacattttt tacataaaac gaagcatata aatttcaacc ttatcttgta
     3721 tggttcttaa tacttaatga gtagcttaag tatcaatcat tataaatttt tcccttacat
     3781 ttaacactct taccatttcc aaaatataca aaatatattt tgaacatttg tacaatgatg
     3841 aaatacaata catgaaaata caatatcata actgttgtct aaaaatagaa gttcttcaac
     3901 ataacctttc acaaaaaaca tattatctaa gtattttttg tctgctcctt gttttcctgt
     3961 ttgtagcata taaattactg catctaaaca tataactact cacacgaaaa aagaaaataa
     4021 acttccaaaa tacaagctct aaaaactacc tctaaagttg tataatgttt actaggaata
     4081 aggttgtata acatatagtt taaataatca ttttttaaaa ttgcaagtta ttgctttcaa
     4141 aattagatgt ttttatatca aataaatgat taagaatttc taaatttaat ggctttataa
     4201 tgcactccct ttctttggga taaaataatg ttgcacagat actttttcta aagataacaa
     4261 ttttattttt ctatcaattc caccagcata cccagtcaaa ctcccatttg ttcctacaac
     4321 acgatgacat ggaataataa tagagattcc attatgccct actgcaccac cgattgcttg
     4381 tgctgacatt ttagatattc ctttttgttg agcaacttta tatgcaattt ctccataagt
     4441 gattgtttta ccatatggta tttgttgtaa aattttccac actgtagtct gaaaaggagt
     4501 acctaccata tggagtgatg gtgtaaaatt gggttctttt cccgaaaaat aaatatctaa
     4561 ccatttcttt gtctgctcga aaattggcaa ttctttttct tgatgttctt ggtcaagatt
     4621 ataagcataa tacttttgat tctcaaacca aagaccagtt aacccaatat tatctgatgc
     4681 taaaagaata tttccaattg gactatggta atagctaata tattgcatac aattcctcct
     4741 tatattctga aaacttcact caaatcatta gacacttctt ttctatctac cattatgtaa
     4801 aaacatacta atataatttc cttctaacta cactttcgtt ataatatcta tcctcatatc
     4861 atattagttt tatatttacc tgcatctgtt catccttttt tccctttccc tttgatgaat
     4921 ataaaattca tacatttaag cttcctactg tattaacttt tatagaagtg tatattataa
     4981 ttttatcact aaataggcca aaaaaatatc gatatagcat caagtaatat cataatactt
     5041 tcaaatggga aaagtaagaa taggctgtaa aaaagaaaag tatttttatg ttagaaatcc
     5101 agtaaaatca ttagtagata gaataacaga aaacgaacaa tttgctattt atcattttac
     5161 acataaatat aattgacgca ataaagtgtt ttctattcta caacgattaa taaggttaga
     5221 aaaaagtaaa aatgaactgt atatgtatga agcattagtt tctgtttctt tcctttggct
     5281 tattatgata aaaaatattg ttttgctacc aataaaacac aaaaatataa ttaatatcca
     5341 tatgcaaaaa attttacgtt atattgaaaa atactattgt tttacattat attgaagggt
     5401 actattgtga aaacttaatt ttggagtact atcaagcagt ggtaatatca ataaatcaga
     5461 gtgctccaga tgatttgaac taagtttaaa tactatacct tataaatatt ttactgagtt
     5521 ttgtttatta aaagcaactc aatttctaaa aggcacaaat gagctaataa gtgacattgc
     5581 tataaaagtt gtttttcatc aaataatcta ttttagtaaa tgttttaaag aaaaaacggg
     5641 atattctcca aaagtgtaca gaaatataaa aaaagagata tgatttttta tttcttttga
     5701 ttatccaaag agtaaataaa aaatattgta aaaaacttac taacaacggc aatgctttga
     5761 actatggtaa tactttgaac ttttgattgg actttttttg ctaaaataat atatttaaat
     5821 agcaaagtaa tctgtttaat caataaaaaa taagagataa aagaaatcaa ctaaaacttt
     5881 tacctcttat tttgatagtt tatcagagct aatatttaca ctctttttat ttttgatact
     5941 tcattaaaaa tgatgcttac tctccattca cttttaattc ttcattaaaa atgatgctta
     6001 ttctccattc acttttaatt cttcattaaa aatgatgctt actctccatt cgcttttaat
     6061 tcttcattag aactatgctt actctccatt cacttttaat tcttcattaa aaatgatgct
     6121 tactctctgt tcacttttaa ttcttcatta aaaatgatgc ttattctcca ttcactttta
     6181 attcttcatt aaaaatgatg cttattctcc attcactttt gattcttcat taaaaatgat
     6241 gcttattctc tgttcacttt taattcttta ttaaaactga tgcttattct ccattcactt
     6301 tcaattcttc attaaaactg atgcttgcac tctgtaaact cataaacatc cattaatgct
     6361 tcaccaaatc tttgatagtg aactacttcc ctctcaccca aaaatctcaa tatatctttc
     6421 aaatcagggt catcagttaa atttattaat tgatagtacg tagccaatgc tttttgttca
     6481 gcagccatat cctcatgtaa atcagttacc gaatcgccaa agacattaat ataacttgta
     6541 gtaaagttta ctccattaga atctactggc tgaagaccat gtccaaaatt agcataatta
     6601 ctaccaagtc cagcagcctt aagctcttct ggagtacaat tgcctattaa ttgatataac
     6661 actgaagaaa ttatctcaac atgagccatt tcctctgtac ctatatcagt taaaagtgca
     6721 cgagattttc cagttggcat agtatatctt tgttgaagat atctagttgc agctgccaac
     6781 tcaccattag gtcctcccaa ctgagtcatg atatattttg ccattctagg gtctgcttgt
     6841 cttatgttaa ctggatgttc cagtgttttt tgataaatcc acatattatc ttactcctcc
     6901 ttaatatata tttaataata aatctaattt taaagtttaa taattttatt tataaaatga
     6961 tttgtcccat ggccaaggtt cagatatcca tgaccaagga tattcacttg attcatatcc
     7021 aaaattagtt aatgctccat atttagattc ataatcacac acagcttgtg taaatttatc
     7081 gcagtatctg ttgtatgaat caagagcttt cttatccctt ggattgttat ctaaatataa
     7141 atttaattct atacaggcaa attgatattc tgaaattctc tctaaaagtt ctcttctatt
     7201 taatgacatt agtacatgtt accccctttt ttagctctaa ctctattttt aggatttgca
     7261 tatagccaat cattatagtt atttgactct attaaatcta attcaggaaa taaagtacct
     7321 ctttttaatg ctgtttttgg attgtatgtg tcatcataaa tttgacgatt gatgtatggt
     7381 ctagcaaatt cacaacaata gtcttgttta tcctctttta aatatcccat taattatcct
     7441 ccttaatttt tagaatttta aaatagcatt atttttaaaa attgtatact ggttctatat
     7501 tataactggt agttttaata ggtctttaat aagattaaat gattaaataa gtatcttttt
     7561 ttcttatttt acctctaaaa tttttctaat taatctttca taaata
//
LOCUS       DAYAKB010000128         7293 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.129, whole genome shotgun sequence.
ACCESSION   DAYAKB010000128 DAYAKB010000000
VERSION     DAYAKB010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.129"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            240..1067
                     /locus_tag="ACGI3L_003522"
     CDS             240..1067
                     /locus_tag="ACGI3L_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HFG9199201.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2092..2556
                     /locus_tag="ACGI3L_003523"
     CDS             2092..2556
                     /locus_tag="ACGI3L_003523"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9199202.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(2823..3467)
                     /locus_tag="ACGI3L_003524"
     CDS             complement(2823..3467)
                     /locus_tag="ACGI3L_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199203.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMVPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3397..4686)
                     /locus_tag="ACGI3L_003525"
     CDS             complement(3397..4686)
                     /locus_tag="ACGI3L_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199204.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4683..5555)
                     /locus_tag="ACGI3L_003526"
     CDS             complement(4683..5555)
                     /locus_tag="ACGI3L_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199205.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(6085..6576)
                     /locus_tag="ACGI3L_003527"
     CDS             complement(6085..6576)
                     /locus_tag="ACGI3L_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HFG9199206.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT         2667 a          985 c          840 g         2801 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatgt
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttggtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattacttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taaaaagttt
     1441 acatctatat taatttcata aaacaatcaa ggtagtcaag agattcaact ttacttgatt
     1501 ttaaaaattt aagtgaattt gttcttatac acatcttttt aaaattatat ctgtagaaaa
     1561 tatcatttag agctataatt aaattaactt attaaatttt agaaaattta ttaaaaaata
     1621 taagttaaat taatattttt aaagattctt ttttgtaact actagaatag taatttagta
     1681 gttattgtat ctctaaagtt taagcatgga tagatataca tttgataatt tgcctataat
     1741 ttacctacta cttggattat tggagcaaat acaatatatt aataataagt tcctaaaacc
     1801 aataaattaa ctaatacaca taaagatatt gatgttgatt atacaactat aagaaacgga
     1861 tttaacagaa tttaatcaag ctaagaaatt atatatatat cgtgatgttt ttgaattaga
     1921 aggtaattca aaattagttt atagtcttct gtcaatccaa taaaaagtac agggtacaag
     1981 aattgttagt aaaattttta aagattttat ggataaatat aaatagtttt acttattttc
     2041 taaaacttta aaataccatt aattacctta aatattttaa taggaggaca tatgaattta
     2101 aataaagtta aatttactga agaacatgct attgaagtta ctaattggaa atatgaaggt
     2161 aaatattcaa tatacaatct acctccatgg gaggaaatta aaaagaagaa tttttcacta
     2221 gcaaaagaag ataaaagaaa aaattttata agttttataa atgacaataa agaattgata
     2281 ggttttataa acttattaga tgaaggaagc tctgtattct ttggtattgg tatgaaaccg
     2341 aattattgtg gaatgggaat tggtaaagaa ataattggcc taggattaca agaatgtaga
     2401 aataaatata gtactaaacc aattgtatta aatgtaagaa cctggaacat gagagctgta
     2461 aaatgttatg agtctcaagg atttaaaata gttgagacta aggtacaaaa aacgcattta
     2521 ggagatggag aattttttgt tatgaggtat caatagttta taacaatagt cttattgtta
     2581 atacaacaat taaaatgaaa aaatacatat gtgtaggtca tagcaataag tgtctttgaa
     2641 atataaattt gagagctttt gataaaattt tgtatacata tatattttat actacggata
     2701 tataaatcta tctacatata taaagagatt gtaagtaggt ttgtgtatat aaaaatagat
     2761 ttatatttca taaatgtact ttttatttgt attaccttta ttttatctaa gctctcattt
     2821 tattatctaa tcttcctttt tactggtttt attaagagag atgcaattat caacacaaca
     2881 cttccaagta tcagccaata tttctcatca aaactacctt gactcataga cattataaaa
     2941 aattttccaa catacttgcc tttagtcatc atatttaaaa ttaaatatcc tatagatatc
     3001 atataaccta tgattgtatt attaaataaa tttgagaaaa acattcctaa acttcctata
     3061 aacatagctg atgcgaaact tccaataata tactcaacta ctggaaaatt acatccaaga
     3121 tatattaaaa catttacaaa acctatgatt aataccacta tacctataat tgacatcagt
     3181 atcctaatta attgtacaat aacttgagat aatgcttttg aagatactat ctcatcaatt
     3241 tcttttgatt gctctagcga aaatacaggt accaacatta ctatccctat tattgcaaca
     3301 taattttcta aacatatagc tgttgaaatt ctgtctaaat tagctactcc ttgtattaga
     3361 ggaaccatac atagcaatat aattgaacat attaaattag ttaaagtgct taatttgaag
     3421 ttttctttta ttagaactaa acagttttga aaactttgcc caaacatcaa gattccccct
     3481 tcttttttgc tcatataaga atatagctaa caaaacaagc accaatgctc ccaagcttat
     3541 cacaattcta ttaatcataa tttgattgaa gttttgtata ataatatccc catttaatac
     3601 actattatgt cttatcatta gccccattgt tgaataatca cctttgagtc ctgtagaatt
     3661 tatactgtaa agccaccaaa ttaattgcac aataattgct actggtgtat ctgttaatat
     3721 agtaatactc attcctacag ctgtaactat cataagagtt ggtagtatcc accataatgt
     3781 atattttata aatgctaagt tatcaataga tataccttta tctttagcaa agaaaatcaa
     3841 aggaagtaaa tctttcatac ctaaaattaa tacaggcaat atcatcataa agacaagtgc
     3901 aaaatatctt gataaaacta ttttgcatga agatacttgt tttgaataaa taatctctct
     3961 cattcttgaa cgcttatctt taagtgacat aaaaactgcc acaaatactg gaaatatact
     4021 taaaactata cctatataat cgcaaaaaat tcttgcatac ccattactaa ctttatcttt
     4081 ttgtattgta tagttgtaat tcttcatagc ttcatcatag gtaactggaa ctactccaaa
     4141 tctttgtaac ttgtcaaaag catatgcaga ccctcctcct aaaatgtcgt ctactctttg
     4201 cattatttct tcaaatcttt caagagatac tttagaataa tctattttta tactttcatc
     4261 agttttccaa agtgaattta tttcgctaat acttttacca gttatttctt ctatatattt
     4321 ttctatggtc ttcgttttat tttggtctaa ttttatatac ttaactaccc ctgttggata
     4381 cgttgtatat gtgttttttt gatattctct aattaggttt atagttgcat ttggaatgac
     4441 cttttctgtt ttcatagatt ctttttgacc atatggatat tgattgtgta cagaataata
     4501 ttcctcaata ttctctactt tttgtggagc aactaatgga tttccatcat taggaatatt
     4561 tttacttaca tcatttgaaa ctgaacttcc aagttgagaa atatagaaaa aaactaaaac
     4621 tacaataaaa atataatata ccatactctt taatatattt ttacattctt ttataaatag
     4681 attcatatat tatctcctcc cattataagc atatagccat cttcaatagt tggattacaa
     4741 tttactgctg tctcaaaagg tttatcatct gatataatcc taagtatagc ctttccacca
     4801 tgagtcaaca ttcctataac tataaatcta ctttttatat tttcaatgtc ttttttatct
     4861 acttcaatac tatatacttt cccttcagct agttttgcta atgcttctgt tgagccattg
     4921 tatatgactt ttccactatt caatatagct acgttttcac atgtagcttc tatatctcca
     4981 acaatatgtg tagataaaat aacgattcta tcatttgcaa tttcgcatag taaatttcta
     5041 aatcttatac gttcttctgg gtcaagacct gctgtcggct catctactat taaaactctg
     5101 ggattatgaa ttaatgcttg tgctatccca agccttctat tcatacctcc agataaagat
     5161 tttactttca cattttgata attagtaagg tttactttgc ttaataactt tgctataatt
     5221 tttcttcttt ttcttagtgg tatatccgat aaaactgcta aataatccat tgctttatat
     5281 actgtcatgt taggatacat tgaaaaatct tgtggcaaat aaccaaccat atttctaatt
     5341 tccttagtat tctcaatagg aactccacac atatgtattg aaccttctgt ttttgataat
     5401 aaagtggcta aaattctcat aaatgtggtt tttcctgctc catttcttcc taaaagacca
     5461 aacataccac tgtcgatttc aagatttata ttatcaagag cttgtttttt cccaaatctt
     5521 ttactaagat tggatactgc tattttcatt tccatatata aatacacccc cagaaacaat
     5581 tttatagaat tttattttta taaattttta ctgtattttc ataataaatt ctaaaactta
     5641 agatattatt tataaatttc taaatttttt ctaaagattt taatttttct gtttttaatt
     5701 aaattaaagt atctttgttt ctgaaatttt ttaagtttat gaagttataa tttaatatat
     5761 atttatttta tttgtgagtc tatttttata tataatgaaa aatgtgataa gtatccaaaa
     5821 gaattactgg atataatagg atagggtatt tagcctttta agataaataa aaatatctac
     5881 aactatatat tgcaaaaatt taaaactaat ttatatatgc taatataaat atttataaag
     5941 acataagaca aatttaccta cagatttaaa tttaacttat atattttaaa aggctaatat
     6001 aatatgtatt ttcttctata caatcaaaag gcttcatatc taagatatgt gatgacacta
     6061 atattcacaa ttttttagta attatcacat tataaaaaat attacagcta gtccatcatc
     6121 agatgcttct tgtataaact ttttaagctc aattagattt gcccatacat attcaaaaaa
     6181 atcatcttca ctctcatcat tcataacagg ataaatatta ttttctaaca tctcattaat
     6241 attaaatctt tttctaaatg cttgttcttc caaactgttc attgcttttg atagtttttt
     6301 tacatcattt gctgtaatca acatgacagg aaattctcca tcaatttcca taagtatgtt
     6361 tccacttagt actaatttgc taaatatatt atcatcatct ccaccaaaag gacaacctgt
     6421 caaagtaaag tgaatggcat gccatgcttt atcaatattg atagtactat tttcgttggc
     6481 atcttcaaaa acaaaatctt gtaagttttc ttctgcttgc tgtaatttaa aaacattctc
     6541 ttcacttatt ttagtataac atcctatcat ccccataatt acattcctcc taagtagcgt
     6601 ttttttaatt gtaacttata attaaactta gttacaataa aatatattga gaaaagtatt
     6661 atttcatctt aaatttaaat acctatatta tcaactaaaa ttctgtgttt atagcgtaag
     6721 tattattatt ttttcctaaa aattaaatga atcagaagtt ctataggcaa tattgactat
     6781 aaataagaac tattactttt aaaaaaaaat ttaagaaatt atactgtaga atcatgctct
     6841 acttattagc tttaaataaa aaataaatca tgttctcaaa ttaaataata aataacaata
     6901 aatttaaatt ttaaactata agagtttctg aagtgttaat aagcatacca ataattatat
     6961 gtgtaagaat ttgatttaat agatatgaat aatttttaca ttaattataa atatattaac
     7021 ctattgttat aaattctaaa aaagaaaagt tatcttaaat aaaaaataag tgtatcttaa
     7081 attttaaatg atacacttat ttttatattg aaattatatt ttttaatatc tattcttaat
     7141 taggtatttt taaattatct gtttacatta aatatttctt aattacttat ctttcagcta
     7201 gctttttcta ttaaatgttt ctcaattact tatttttcaa ttagccactt atattaagca
     7261 tttcttaatt acttattttt caattagcca ctt
//
LOCUS       DAYAKB010000129         7256 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.130, whole genome shotgun sequence.
ACCESSION   DAYAKB010000129 DAYAKB010000000
VERSION     DAYAKB010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7256
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.130"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(322..1713)
                     /locus_tag="ACGI3L_003528"
     CDS             complement(322..1713)
                     /locus_tag="ACGI3L_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HFG9199207.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(1724..2944)
                     /locus_tag="ACGI3L_003529"
     CDS             complement(1724..2944)
                     /locus_tag="ACGI3L_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HFG9199208.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(2958..3746)
                     /locus_tag="ACGI3L_003530"
     CDS             complement(2958..3746)
                     /locus_tag="ACGI3L_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HFG9199209.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(3763..5037)
                     /gene="larA"
                     /locus_tag="ACGI3L_003531"
     CDS             complement(3763..5037)
                     /gene="larA"
                     /locus_tag="ACGI3L_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050043 - lactate racemase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HFG9199210.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(5155..5868)
                     /locus_tag="ACGI3L_003532"
     CDS             complement(5155..5868)
                     /locus_tag="ACGI3L_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFG9199211.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            5993..7252
                     /locus_tag="ACGI3L_003533"
     CDS             5993..7252
                     /locus_tag="ACGI3L_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HFG9199212.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
BASE COUNT         2185 a         1308 c          828 g         2935 t
ORIGIN      
        1 ataaagattt agtaaaaggc cctatggatt tttatactca tccaatatat gtaaagtagt
       61 tttttaaaat aactatattt ataaaaatca ttttattaac tctttattat ataagataca
      121 atagtcttac tttatttatg tacacatgct tttaggatga caacatcaac ttaaatatta
      181 tgttactttc taaatttaag taaatattgc catcctaaaa attttacaat ttagcttcag
      241 atttaaaagt aaagtttaaa atattatatt taaatctaat ttaatatttt ttgttttata
      301 aatattatta aattaatatt tctaatatat tttccctgga tttaaaatat ttttagggtc
      361 aaaagctaac tttatatttt taattaacat catataagca tctgaatttg attcatgtaa
      421 gtactctttt ttagcatatc ctatgccatg ttcaccagaa acttgaccac taagttctct
      481 agatttttta tacatatagt caaaagtttc ttttaatctt attttccatg tattatcatc
      541 cataccatct tttaaaatat atatgtgtag atttccatct cctgcatgac caaaactttt
      601 tattcttatt tttaatttgt cttgaagctc gtgagtgtat cttataaact ctgctatctt
      661 atctcttgga acaacgacat cacattcatc catttgtgtc gtagatgcct ttatagcttc
      721 taaaaatgca cctctggctg accatataga atcgtttctt tcttgtgtat ctgatataaa
      781 tacatctaat gcaccatttt ctaaacataa attagctact ttttcatatt ctttttctat
      841 atcttcagtg ctatttccat caaatgtaag caaaagataa gcatctgatg tattatctgg
      901 aaacttttta cctaaaaatt cttctgctgc caatatcaca tctctttcca taaattctat
      961 agccgttggt attgattttg attttattat tttaggaaca gtttctattg ccattgataa
     1021 atctggaaat ggtataagca aacttatact tttctttggt aaaggaagca attttaatat
     1081 agctttagta actattccta aagtaccttc tgagcccact aataaatcct ttatactata
     1141 tccagaacta tttttaacca cctttccacc tacatttata atttctccat ttggtagtac
     1201 aacttcaagt cctcttacat aatcccttgt aacgccatat tttactgctc tcataccacc
     1261 tgcattagtg tttatattac ctgcaattgt agcacttttt tcacctgggt caggtgggta
     1321 aaataaatct ctatcttgaa catattgacc tattgtcatc aataaaacac ctggttctac
     1381 tgtcaatgtt aaattttcat aatcaacttc aagtatttta ttcattttac atagattaat
     1441 cattattcca ccatttatgg caacagcagc acctacaaga ccagtacctt gacctcttgg
     1501 tgtgactggt atattatttt tatatgcgta tttcattatt ttagatactt gttcagtttc
     1561 aagtacattt actaaaactt cagggtactt ctcaatccct ccaagttcat catgtgaaaa
     1621 atcttcattt atatcacttc caactaatac attttcttct ccacaagtat ctattaaaaa
     1681 atctatatct tttttatcga ttaatttata catttctatc cccctattta gctgctgatg
     1741 ccatatattt ttgattatta tctttgttat tttctatttt ttcaatcaat ttaggaataa
     1801 tatcataaat atcacctatt aaagctaaat gtgctacatc aagtataggc gctttatcat
     1861 ctttatttat tgctactata tagtcagcac cctgcatccc tgcaacaaat tgaactgctc
     1921 cagatacacc acaagttatt atcaatttag gttttacagt tctaccacta agacctattt
     1981 gttttttagc atctatccaa cctgcttcta ttacaggtct tgttcctgcc acttgagcgt
     2041 ttaacttatc agctaattta tatatcatct ccatatcttc ttgttttttt attgctctac
     2101 ttgccacaac tatcacttca gcttcttcca gaccaacttc tttatttttt tcttttacac
     2161 tcagtacctt aattttagat tttagttctt ttttttctac tttacataaa gttatctttc
     2221 ctgtagtatt ctctattttt tctggtgctg aaaatatttt atatcttaca gtggcaaatt
     2281 gtggtctatt attaggtgtg tttatatgag ccattatatt tccaccaaat gctggtctta
     2341 tttggtctaa atcagtattt gattgaatat caagtattgt acaatctgct gtaagacctg
     2401 ttctaaatct agcggcaagt cttggagcta atgacctacc taatgtagtt ccaccaacta
     2461 atactatcgt tggttttatt ttatctataa agttttctat tgcttttgaa tatggttcta
     2521 tcctaaaatc tttaaattca tcttcatcat atacaaatac ttcatccacc ccataagaaa
     2581 tcaaattact gcacttatct tttatgtctt ttcctacaaa tacacaatac acaggttgtt
     2641 ttatttttga tgccatctca cgagctttac ctataagctc gtacgttaca ggatgtatat
     2701 ttccattatg atgttcaaca tatactgcaa ttcccctcca ttcatcttta ttaatttgta
     2761 ctttactact ctctataaat tcaaatgcgc cttttggtcc acttttgaca cacaacttgc
     2821 acatcttaca gccagcactt atttctacta tacctgactt ttcttctata gccccaaaag
     2881 gacatatttc taaaattctc tttaagtcag ttattttatc ttgatttaca actatctttg
     2941 acatttatta ctccccctta caccaacttt aattcctcta atttatttac aagtgcaaaa
     3001 cttagttcat ctgcatttcc tcttacaata tttttatctg tatttggctt tggaggaaat
     3061 attcttacaa cttgagtagg agaaccatta agtccatagt tattttcatc tttatcttca
     3121 aagtcatcta agctatatac aggtatttct ctatctttag tattaagttt taatttaaat
     3181 gaaggtagtc ttggttgaaa aatgtctttt tctacagtta ttaaacatgg atattcaatc
     3241 tcacatactt gtaaatcatt tggcatatct atttcaacaa ctatactttc atctttaact
     3301 tcaattaatt ttgtaacgtt agtaacatga ggtatatcta aaaattcagc tacttcaggt
     3361 cccacctgtg ctgtatcacc atcagtagtt tgttttccac aaattattag gtctaccttt
     3421 cccatcttct taataccttg tgatatggta taggaagtag ccaatacatc tgctcctcca
     3481 aatctcctat cacttattaa tgctccttca tcagctccca tcataaaact ttcttcaatt
     3541 accttctttg cctgaggagg acccatgcta agtactttta gattcgcttt cttatcttcc
     3601 tttattctaa gagctgtttc taaagcatat aggtcatagg gattcatttt tgaatctact
     3661 ccatctcttt ttagtactcc tgtagtttca tcaacttcta ctgaagtcgt tccaggaact
     3721 tgtttaatac atgtcaaaat ttccataaag tacactcctt ttttatttaa ctataactga
     3781 tactccatca ggtataacta ctactttgct ctccttacca actatactat tcgccatttc
     3841 taaagcttct ttaaagttaa atgcatgttt catatgcatt ttttttatca tttcaggatt
     3901 acacttatct gttaccatta tcacagtata tttagataat attctcgcta gtatctgaaa
     3961 ttcccattgg tctggaatcg tatctactct atcgacactt ctaattttat ctaaaagttg
     4021 ttttggagaa tctgcatttg ctacattttc ataaaaagat tgacctccat gaccatcatt
     4081 acatgctgaa atcattatta ttactccacc gtctttacaa gtagcttcag ctgctgtcat
     4141 tcctttaaca gattgataaa tattttggtc tagtggatat ccaccatttg tagttacaac
     4201 aatatcagat tttatagaat ttacttttga taactctgtt acaaatctac atcctttagt
     4261 atgtgctttt tcgacatcac cagcaaagga agcaattatt tttttatctt tatctattac
     4321 aacattcaat atgaatgcta attttgcaac tttagctgca tataccatat cctcatgaat
     4381 aggattatta ttcaattttc cagttcttga attatcacta tctataaagt cactacaatg
     4441 attgtacatt atagtctttg cagatgcgat tcctggaagt acactttttc tgccacctga
     4501 aaaacctgca aagaaatgag gttctataaa accttctgct atcaaaagtt ctgcctcata
     4561 tgctagtttg tttatatata aatctccacc tgaaggcaat atccctactt tacacataga
     4621 tttatcatca gtagatatat gcataactat atcttcatta tctactattt cttctcccat
     4681 tttataaatt agctcttccc ttgtacttgg cctatgaaat ccagttgcca ctataatctt
     4741 cacatcaatt tctggattaa cattcctaat ccttcttaat ataattggca tagttattct
     4801 acttggtaca ggtcttgtat ggtcacttgt aattatgact acattctttt tccccttaac
     4861 cagttcttcc agagaattag agcctatagg attattcata gattcttcaa ctatctcttc
     4921 ttgagtctta tgttctatat aattatccga ttttgactcc aaaacaccga gaaaacgttc
     4981 atcaggtatt tctaaaatca ttccttgttt tgaatacggt acttttaact ttaccatttt
     5041 taatctccca ttataataaa ctataaaatt ggtatgtggt cataccagtt ttacatttat
     5101 atgatagtac cattatctac catttgcaag aataatttat tttataacaa acttttaatt
     5161 ttcatttttt ctataatttt tacttataaa atccatatgt tcctttgctt tctcacatgc
     5221 aagttctaca tcattttcta caactgcatt gtatatagct tcatgctgtt taagcaatat
     5281 attttcatta aaaggttctg cgattatttt ttctcttgca tcttctataa atccatcaaa
     5341 taattttgat gctgtcataa aaagactttg aattaaataa tttttactta atgttgctag
     5401 tttactgtga aatttttggt ctaataacac cagtactcga ttattatctt ttttattagt
     5461 ttctaccctc atttcatcta ttatatgttt caattctata acttcagaag aagttattct
     5521 ctttgaagca agttttgcaa tctcaatttc taggattatt ctaagctcta atatatcttc
     5581 aagtgtacca ttattaagtt taaaaatcat agataaaggt tctattaaag ttttttctat
     5641 atttgtacat ataaaatttc cttcaccctg tctgctttct atcactccca tagtctctaa
     5701 taccctaata gcttccctta tggaagttct actcacattc atttgttcag acagttctct
     5761 ttctgatagt aatttatccc ccttttttaa ctctccattt agtattttat attgtatttg
     5821 ctcaattact tgttcataaa cttttttact agctatacta ttaaacattt tttcctccaa
     5881 tatgataatc gttgttgtaa tatatatcta ttatatatct taagccatta cattcatata
     5941 tttttattac ttttaatata atatcttata actcaaattt acaggtgata ttatgaaaaa
     6001 aaataaaatt attgcttttt ttgctccatc tatcatagtt ggagttctag ttttagggat
     6061 tatcctatac ccaaatgaag ctataaaatc tgcaagagaa ggcttttcta tatggtctaa
     6121 tgttttagtt ccatcactac taccatttat aattggagca aacttaattg ttgatttaaa
     6181 aatagtggat attatagggt ttatcatcaa tcccataact agatttgtat ttaatgtttc
     6241 aggaaagagc gctttagctt ttgctatatc tacagtatct ggttatccag taggagtaag
     6301 tttagcttct gaatttagga gtaatggaca aatttctaag tatgaagcac aaagacttgt
     6361 gtctttttgt tctacatcag gacctttatt cataataggt tcggttggta caggtatgtt
     6421 ccaaaattca aacttaggtt atttaatgat tctctgccat tatctaggaa ctatattggt
     6481 tggtcttttc tttagaaatt atggtaatga aaatcttcca aagacaaaat tggatttaaa
     6541 aacaaatata aaaaatgtaa tcaacattag aaattcaagt gggaatggtt tttttgtttt
     6601 atttggaaat gctgtattta atggagtaaa tacattactt acagttggtg gatttgtaat
     6661 tgttttttca gtagtattta aaatactatc tctttttaat gtaatctcat taatagcatc
     6721 agttatatat ttgcctcttt catttttagg tgttagtaaa gaactctgtc aagcatttgt
     6781 aagtggtcta tttgaaatta ctataggatg caataaagta tctagtataa caagttctcc
     6841 agaaatttta agagcatctt tagctagttt tttgatagga tttagtggat tatccatcct
     6901 agctcaatgt tgtacatttc tatcaaaaac ggacatagat ttaaaattat acatactaag
     6961 taaatttgcg catggagttt tagctgctat ctttatattt atactttatc caattgcaaa
     7021 ctctgctgtg ttggtttcta gctttgctga tacatacaac gttatatata ataatttaat
     7081 ctggttttat tatcttagct attatgatac aattcttcaa attgtagtaa taatttatct
     7141 aatctcagcc gtatttattg caaaaaaaca tatgaaaact ttatctacaa atgggaaact
     7201 aatgcgatat aaaaatactt ttttcactaa gaaattttca cgaaaaaaat aaaact
//
LOCUS       DAYAKB010000130         7208 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.131, whole genome shotgun sequence.
ACCESSION   DAYAKB010000130 DAYAKB010000000
VERSION     DAYAKB010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.131"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(7..531)
                     /locus_tag="ACGI3L_003534"
     CDS             complement(7..531)
                     /locus_tag="ACGI3L_003534"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9199213.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(584..808)
                     /locus_tag="ACGI3L_003535"
     CDS             complement(584..808)
                     /locus_tag="ACGI3L_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199214.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            1005..2129
                     /locus_tag="ACGI3L_003536"
     CDS             1005..2129
                     /locus_tag="ACGI3L_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HFG9199215.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISTFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSDSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(2603..3427)
                     /locus_tag="ACGI3L_003537"
     CDS             complement(2603..3427)
                     /locus_tag="ACGI3L_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5780 domain-containing protein"
                     /protein_id="HFG9199216.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(3775..4830)
                     /gene="ispG"
                     /locus_tag="ACGI3L_003538"
                     /gene_synonym="gcpE"
     CDS             complement(3775..4830)
                     /gene="ispG"
                     /locus_tag="ACGI3L_003538"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HFG9199217.1"
                     /translation="MSYERRKTREVSVGAVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(5013..6017)
                     /gene="rseP"
                     /locus_tag="ACGI3L_003539"
     CDS             complement(5013..6017)
                     /gene="rseP"
                     /locus_tag="ACGI3L_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFG9199218.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(6030..7184)
                     /locus_tag="ACGI3L_003540"
     CDS             complement(6030..7184)
                     /locus_tag="ACGI3L_003540"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HFG9199219.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
BASE COUNT         2356 a         1295 c          730 g         2827 t
ORIGIN      
        1 gcttctttaa attaaatttt tattatatct tcccataata taaacatctt caaattttcc
       61 atctctgatt acagcatatt ttttagttcc ctctatttca aaacctagct ttttatataa
      121 atttaatccc ttttcattat ccacaattac ttctaatcct actctagtta acataatcca
      181 attatctgct atatctaaaa gttgttccat aagcttctta cctactcctc ttccctgata
      241 attctctgca acacttattc ctatttctgc gctatgtctc aatcgtggag aagaatttac
      301 atgtaaccca gcaaaaccta ttacatcttt ttctccatta ttattagttt cagctacaaa
      361 catataatca ttttctccca aagaagctaa catagcttca gttttatcga ctctgtcact
      421 cattaatgcc aaagtatttc tcataacact gtatgttctt ctaatttcat taaaagcttg
      481 tgcatcttct cttcttatag gtcttattgt tatatctata ggcttactca tattggattc
      541 cccctcaaac ataatcttta tttttaatta aaattttaca tctttatttt atactgttca
      601 aatctatgta tgcttctacc tgaggtacat atatcatatt atcttttata tgtgtacttc
      661 caaattcttt taattctgta ccttctttat ccttagttat tttatatcta atggattcca
      721 taccttcaac tacttcagca tgaaaaaaca taccttcata ttgtttaaat ctaaaattaa
      781 aattgtcttt agtaagtttt attatcatat ttttatctac tccttatata attgatattt
      841 ttcttattat tagttgtata tatactgctt attcatatta atatattata acttatcatt
      901 tatttagtat aaagttataa atagatatat ttatacttat tttacaatct ttcttcaatt
      961 gatatataat atgtttatat aaactaatgt atgtgaggtg aaatatgagc aaaaaaacaa
     1021 aatatttttc tttaattctc tttcctattg ctttgctttt aaattttata gccagtaaag
     1081 ttccaaatat tgttgaaaaa tattactccc aattcataga taaaataatt gtacaaatat
     1141 tgagtaaagt ttctggaatt ttcccatttt ctctctatga gattacaatg tacataatag
     1201 ttatatctac cttcttattt ttatgttgta ctttatctac aatttttaat aagaaaaaaa
     1261 aattaaacat atatttaaaa aattccattt taaatatatt atccattgta tcaatagtct
     1321 actttctttt tgtagtgctt tggggaataa actataatag gattccacta gaaaccacac
     1381 ttataaataa ctataattta aaaaacaata cctctatcca atcaaaacaa tatagtgtta
     1441 aagagcttac taaattatat aaattccttg taattaaagc aaatgaaact agaaaactca
     1501 cattacaaga taaaaatggt attgtaaaat ctaatacaga ttataatggt gtcataaata
     1561 gagctcaact aggatacgat aatatcttgg atatattacc tggtgttagt gatagttatt
     1621 ctaagcctaa gtatattatt tcatcaaatc taatgtgcta tacaggaata actggtatat
     1681 actttccttt tacaggtgag gcaaatgtaa atatagcaat acctgactta tatattcctt
     1741 gtacagttga acatgaaatg gcacatcaaa ggggatttgc tagtgaagat gaagctaatt
     1801 ttatagcgta tcttacttct ataaaacacc ccaatattga ttttaactat tctggatata
     1861 ttttagcttt aaattatact gcttctgctt taagtaaggt tgattataat gcatatgttg
     1921 atatttctgc tggcatttca gattctgtcc gtagagattt aaaaaatgaa agtgaatttt
     1981 ggcaaaaata tgaaggtaaa attaatgaaa tttctaatga gtttaacaat tcttacttaa
     2041 aagctaatgg cgttactgaa ggtactcaga gttatggtaa aatggttgat ttattgctaa
     2101 cttattatga attatatcca tataactaaa cactacaatt caaaatttta ttcatataca
     2161 gctgatatta aatcagctgt tttctattta aataaattat ttaacttcaa gcaatcttat
     2221 ataatttgat agtacttata ctatctgtat aacatttcaa ttctaactat tttagttaaa
     2281 acatttctat tatctttttt aataaatgtt ttaactaaaa tttttaaaac ataaaacttc
     2341 cacattattt cactatctat ataaaaatct aaaaattcac atataaaatt acataactaa
     2401 aaaatcataa atttatagaa aacatatatt caaaataaaa aagcatgtat caaaacttga
     2461 cacatgctta taatcttatg tatatatatc attttgtcac aataaaaatt tacttgtaac
     2521 actgatattt ttaaacaaaa tagtccttat ttaattaaat taacattaat taaattcgta
     2581 ctcattttgc tatcattaaa cattacttat agtaattttc taatacacta tttgaaactt
     2641 ccttcccttg aaaacttttc aaccaattct catatgctga gtttttccat acactaccat
     2701 cattaaatgt tacttgtttt acacaagata taatgtactt tacaccatgc tctccagttg
     2761 attgtttcca tttatcaaac aatagaaagg catcattttg attcttacct ggtgctattg
     2821 cattttgctt tgcatattct ttctccattt gtttccattc tttcaaccaa ttttctaccc
     2881 atgccttgcc ttgttgtttt tcaaacatac ttattatatc ctgtggtggt gattgttgca
     2941 tttttctata agtatgtgaa tatgattttg gagacacagg agatatgcct gtaacaatac
     3001 catagtctac accagctggg ctaaatccaa cacttcctac ttcgccatct gctgccacat
     3061 tttgagcatc ccaatatagc tcaagtggtt ttccattttt atcatatgct aagcatgtaa
     3121 tttcataatc cataattgcc ttttcactgc tatttgttaa gcttataaca ttgctaggcc
     3181 aatgatatgg agtatcatca tactgtattt tgctattatt tataaataat ggaatattct
     3241 cattataaac aagaccttta ctactttgaa tatctgatac cttctttgtg acagtactta
     3301 ccgtatttgc taagtataca tttgtttttt ctgaattggt cgtactaaga gaaaatgttg
     3361 ttgtcgttcc agtaatcagc aaagcaacaa ctaaaatagg taagctagat atttttttat
     3421 atctcacaat tcttcacctc tttttctatt aacttataat aaaacaattt accaaaacat
     3481 taaaatctat gttaacataa tttaccaact gttctagtaa ctatatccta tcatagttac
     3541 tatcaagttt caatactatt gatggaaatt ttcactatat taaatctttt tttaatttta
     3601 taaatttaca atatgattta actcatacat atatagtcaa attagaatat aagtttctta
     3661 catttaatga agtttataaa ataaaaaatg actagataat taaatactgt aaataaaaac
     3721 ttattacaaa agtatttaaa aatctagtca tttaatatat atatgaattg tatactataa
     3781 tttttcaatc tcttctagca actcatcaac taatttgtta ccatcaatca ttctaactat
     3841 ttcacccttt ttaaataaaa gaccttcacc tttaccccca gcaataccta tatctgcttc
     3901 tctggcttca ccaggtccat ttacagcaca gcccataatt gcaacagtga tatttttttc
     3961 catactacca atcttttctt caacctcatt tacaacacta attaagtcta tattacatct
     4021 accacatgta gggcatgata taactttaat cttatcattt aaaagtccca aacttcttaa
     4081 aatctgttta ccaacaataa cctcttcaac agggtcgcct gttaaagata ttctaacagt
     4141 atctccaatt cctttaagaa gaagtgctcc tacccctata gaagacttta ttgttccttt
     4201 gtgaacactt ccagattctg taattccaat atgaagagga taatcaactt tttttgatat
     4261 taattcatat gcatcaacag ttttataaat atcggatgat tttagagata taactatatt
     4321 atgaaaatct aagtcttcaa gaatcttaat atgtcccatt gcactttcaa ctaatgcttc
     4381 agcagttgca gagccatact tttttaaaag ttctttctct aaagaacctc cattaactcc
     4441 aattctaatt tttaaatttc tttccttgca tttctcaact accatcttaa ctctctctat
     4501 acttccaata ttaccaggat ttattcttat tccatccaca ccttgttcta tagcttcaag
     4561 ggctagctta taatcgaaat gtatatctgc aataattggt atatttacac tagactttat
     4621 ctttgctata tttttagcag ctttaatatc aggaacagca actctaacta tatcacaacc
     4681 agcttcctct aatctcttta tttgagctat tgtagcatct gcatctcttg tatcagtatt
     4741 tgtcatagat tgtatactta taggattttc tcctcctatt tttacagctc ctacacttac
     4801 ttctctcgtc tttcttctct cgtaactcat attccacctc tatatattat tttatattga
     4861 atctctttaa atattaaaat attataacct acatgtatat tataaattaa aaagctatct
     4921 agttaaataa gaataaattt catatataaa aattaattta ttcttattta aaactacata
     4981 gcctattttc ttaaaatctc taaaaaacta aatcattgaa ataatcttag tatatcttta
     5041 tatgtgataa aaagcataaa taacattaaa gctccaaaac caacaacatt tatcatgcct
     5101 tctttatttg ggtcgagttt tttaccacct ctaacagctt ctagtaacaa cataagtatt
     5161 ctccatccat caagtgctgg tattggtaat agatttacta tacctaaatt taagcttatg
     5221 acagctgcta aatacactac atttatgatg cctgtacgag cagcatctga taccatacca
     5281 ataacaccta ctggtcctgc tacagcattg ccaatccctc ctggtacacg tcctgtaatc
     5341 atttgaccta gaaatgttag catctgtttt gtcatatcta cagtagtttt acatgcattt
     5401 actattgacc ctaaaaagtc tttttctctt tgtggttgaa ttcctatttc atactttcca
     5461 ttgttatttt taggtgttac atttacaact ttatcacttc catctctagt tatactaagt
     5521 tttaattctc caccagaaga agtgtttatt atatttgcaa cttcatccca agtcttaaca
     5581 gaattaccat taattttatt tatcttatct cctacttgaa gccctacagc ctgtgcagga
     5641 gtatctggca ttatctttcc taatttagtc gttggagaac ctatatacaa aaatactgga
     5701 actaaaagta ttgctgctaa tattatattg aatattggtc ctgctacaat agtactaaat
     5761 ctttgtaata tagacttgtt tccaaaagaa tttggactta tttgttcttc atcttcacct
     5821 tccatgctga catatccacc aattggaagt gctcttatag aatactctgt atcttttttt
     5881 acactatata tcttaggccc catacctata gaaaactcat ttactttgat accacttctt
     5941 tttgcaaata taaaatgtcc taactcatgt attaatacaa ttatactaaa tagtattaat
     6001 gcggctatta tagtcataaa ttcaccttcc tattttttta tcagatttgc aacataagct
     6061 ctactccatc tatctgtttc taagatttct tctaatgttg gttcacttat gctactatga
     6121 acttctaaag tcttctctat gtaatatggt atgtcataga aaccaatttt atcctctaaa
     6181 aattcactta ctaaaacttc atttgctgaa tttaaaacag aagaataagt tcctcccatt
     6241 tttaaacact catatgccaa ttttaaacat ggaaaagttt ctaaatctgg ttcttcaaaa
     6301 gttaaagtac taaattttga aaaattcatt ctttcaaagc tactttccat tctatctgga
     6361 tatgtaagag catactgtat tggtagtctc atatctggac atcctaattg agcaattatt
     6421 gagctatctg tatactgcac cattgaatga attatgcttt gtgggtgaac tactacatct
     6481 atattttctt gttctactcc aaataaccat ctagcttcta tcacttcaag tcctttattc
     6541 ataagcgttg aagaatcaat acttattttt cttcccatac tccaatttgg atgcttcaaa
     6601 gcttcatttt tagttatatt tgcaagttct ccctttttct ttcctctaaa tggaccacca
     6661 gatgctgtaa gtattatctt ttctatattt tttttatttt ctccatttag acattgaaat
     6721 atagcactat gttcactatc aacaggaaga atatttacat tgtatttttc tgcttctttc
     6781 attacaagtt caccagcagt taccaacgtt tctttattcg ctaatgctat gtctattccc
     6841 ttctttatag cacaaagagt tgggactaat cctatcatac ctactacagc agttaaaagg
     6901 acatccactt catcaagtga tgatattatt tttaatcctt ccattcctgc taaaacttct
     6961 atttctatat ttttaggcaa catttctttt aattttaatg ctttattttc ctcaaaaact
     7021 gttacatatt taggtttaaa ctctactatc tgttctagca ataattcaat attactgtta
     7081 gctgatattg caactatctc aaacttatct ctatgttctc taaccacatc caaagtttgt
     7141 ttacctatag agcctgtaga acctaaaatt gatatctttt tcatataata atcctttcta
     7201 ataataaa
//
LOCUS       DAYAKB010000131         7151 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.132, whole genome shotgun sequence.
ACCESSION   DAYAKB010000131 DAYAKB010000000
VERSION     DAYAKB010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7151
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.132"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            485..976
                     /gene="infC"
                     /locus_tag="ACGI3L_003541"
     CDS             485..976
                     /gene="infC"
                     /locus_tag="ACGI3L_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFG9199220.1"
                     /translation="MNEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISP
                     NANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTKANNAIK
                     FLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNNMVVIID
                     PKK"
     gene            1004..1198
                     /gene="rpmI"
                     /locus_tag="ACGI3L_003542"
     CDS             1004..1198
                     /gene="rpmI"
                     /locus_tag="ACGI3L_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFG9199221.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1254..1610
                     /gene="rplT"
                     /locus_tag="ACGI3L_003543"
     CDS             1254..1610
                     /gene="rplT"
                     /locus_tag="ACGI3L_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFG9199222.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            1920..2465
                     /locus_tag="ACGI3L_003544"
     CDS             1920..2465
                     /locus_tag="ACGI3L_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199223.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKKDEGK"
     gene            2900..4825
                     /locus_tag="ACGI3L_003545"
     CDS             2900..4825
                     /locus_tag="ACGI3L_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9199224.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5226..7130
                     /locus_tag="ACGI3L_003546"
     CDS             5226..7130
                     /locus_tag="ACGI3L_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9199225.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3011 a          714 c         1354 g         2072 t
ORIGIN      
        1 tagtatatta gagtacaata tagaatttgt tatgtagtat agtagtatat tagaatacaa
       61 tatagaattt gttgggtagt atagtgttat attagaatac aatataggat ttgttatgta
      121 gaatatatag agtcatgtag aatatacata tataaaagga ttttgggtat aaatttaaaa
      181 attaatagca aaatgagtag tatagacata taattagtag taggaagtaa ttaaattttt
      241 cctaaacaaa aaaaatagtt gcaaataatt tgattaagtg atatagtaaa taaggtaaga
      301 ataaaacaaa gaagaagtcc gcttctcacc ttacgccgga ggttagtaag gtaaatataa
      361 gttaaagctt aattttaatt taagtttgtt taaatttggt aacttatatt gcggatgatt
      421 acgtcatccg ctttttattt tataaaaatt ttggaggtgt cctacaatta gcaaagaatt
      481 agcaatcaat gaacaaataa aagataagga aataagagtc ctttcaccaa caggtgaaca
      541 acttggagta atgcctacta aagaagctca agcaatggct aatagcaaaa acttagattt
      601 ggttcaaatc tcgccgaatg caaatccacc agtatgtaag ataatggatt atggaaagtt
      661 tagatatgag caagcgagaa aagagaaaga agctaagaaa aaacaaaaaa ctatagttgt
      721 aaaagaagta agacttagac caggtattga acaaaatgat ttaaatacga aagctaataa
      781 tgctataaag ttccttaaaa aaggggataa agtcaaagtt gaacttagat ttagaggaag
      841 agaattagga cataaagaca taggtaaaga agttatgctt aagtttttag atataataaa
      901 agagtttgga gaaccaacaa aagcccctgc atttgagggt aataatatgg ttgtaattat
      961 agatccaaaa aaatagatga ttaactgaga ggaggaattt gtcatgccta aaatgaaaac
     1021 tcatagaggt gcagcaaaga gattaaagaa aacaggaact ggaaagttaa agagagctaa
     1081 agcttttaaa aaacatatat taactaaaaa atctgcaaaa actaaaatga acttaagaaa
     1141 atcaacttta gtaagtgatg gagatgctaa gagaatagca caattattac catactaaga
     1201 tacagattgt aaataataac tatagaagag ggatataaaa ggaggtcata acgatggcaa
     1261 gagttaaaaa agctatgaac gctcgtaaaa agcataagaa aatattaaaa cttgcaaaag
     1321 gattcagagg atctagaagc aaattatata gaccagcaaa tacattcgta atgaaagcat
     1381 taaaaaatgc ttatatagga agaaagttaa agaagagaga cttcagaaaa ctttggatac
     1441 aaagaataaa tgcagctgct agaatgaatg gaatatctta ttcaagatta atgaatggat
     1501 taaaattatc tggtgttgaa gttaacagaa aaatgttatc tgaaatggct atacaagacc
     1561 cagaaggatt tgcaaaatta gcagaagttg ctaaagcaaa attagcttag tattgaatca
     1621 tgagatgtaa agtctttgag ttatataaat aattcaagga cttttttatt ttttgaaaaa
     1681 tacttattag tgtcatgtac aaccaatttt ataatgataa ataaaataag caatacaata
     1741 gaattttatg agatttatta taagaattgt tacaattatt tatgatagct ataaaaagtc
     1801 atagtaaaaa tgatattgat gtatgttgat atatgtataa agtttccaat caatcttgaa
     1861 ttaatattat caacatgata atattatctt attaataata taaataaggg ggacataata
     1921 tgaatgaaaa actaatggat tgttttgtaa acccaattaa atgcaagtta ttgattgaaa
     1981 ttttttcaaa taatcgaact acagctaaac aattaggaga aaaatttcaa gatatatcaa
     2041 aggcaacact ttatcgttac cttaataaaa tgttgaaaga tgatattata aaagtggttg
     2101 aagaaaataa aataagggga actgttgaaa aagtatatgc tatgaagtta gatatagctg
     2161 atgatgtgaa caaaattata gatgagaact ctggagaaga atatgctcaa ctgtttactc
     2221 aatatatgat gggattttta agagaatttt atgaatacgc tgaaagaaag gaaaaggata
     2281 tcctaaaaga tggttcagga ttttctgtct gtccagtata tgctagtatt gatgagatag
     2341 ttgaagtgag taaaaaaatt gctagtatac tagaacctct aagaaataac tcacatgaag
     2401 aaggtagaag aatgcattct ataggagtga taattactcc acctaaaaag gatgaaggga
     2461 aataaatctg atttacatgg ggtagagcca atttatacag ggaatcgttt tatgatttac
     2521 atatgtatcc agagcaaagt atctctgctt ggattgtact tcattgtacc atttcatcca
     2581 atgacttgga gtggtacaat gaagtttttt aatttttcat attaatgcta aagaaatgaa
     2641 ctttagacca catatgcaat taggttgcat tatacaatta gaccacatat acaaaataaa
     2701 aatcagtatt tttatagcag ataaattgac tgtcattctt cttaaaaatc atctattagt
     2761 tattgttagc atattgaaag aaattatagt aatctattga ataaatgaat attgcctata
     2821 atcatataaa ctgctatagt ttaaaataaa gcaggacgtt aaattttata gtaatctaaa
     2881 aatttaagag ggggatttta tgaaaataaa atttgttatt atgccattgg tgatattttt
     2941 aatggtatta tttgtggggt gtcaaagtac aaaagataca gaagttaaag caaaagatac
     3001 agaaattaaa atattaggga caggtgattt acattcaatt ttgacagact ctatggtttc
     3061 gtatgtaaat gaggaaaggg aaaagaataa aaatctgctt atggtagatg cgggagattt
     3121 ctatggtaca caaagtagag aaatgtggga atggtcttct ggaaaaaagt taattaatat
     3181 taaaagaaat ggtagagcag agtatgatga cataattaag agtagtaaag atgaagtacc
     3241 tatagttaaa gatatggcaa agttgaaata tgatgctgta gttttgggag ataatgaatt
     3301 tgtttcaaat gataagcaaa gtcttgataa actggtttct gattttaaaa ataataatat
     3361 gccattggta tcagcaaata tatatgaaca atctggagaa aattatgtac aaccatatgt
     3421 aatgaaaaat attaagacag atgagggcaa tgtaaaagtt ggaatactag gtcttactat
     3481 aaaagaagta ggggaaaccc ttggtcttga ggattttgaa aaggataaaa aagctagaga
     3541 gcttggagaa caagctgatt acaaaggaaa attatatgca aatgatttag tagaagatgc
     3601 aaaaaaatgg ataaaagtta tggaaaaaga aagtccagac ataatagttg cagttgtaca
     3661 ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat agaataaaag agttagcaac
     3721 tacagtggat ggaatagatg caattgtagc tggtcatact catgaaaaaa tagatgaaca
     3781 caaatataaa aataaatctg gagatgaagt aattgttaca caaccaggtt ggcatggaga
     3841 tagagtatca gagattaatt tcaaactaaa taaagagaat ggaaagtggg acataaagga
     3901 aaagtctagt aaattaaaaa taattgataa agaagtaagt atagttgcta ctgcagattt
     3961 acattcacat ttctctgata aattaacagt tgaccttgtt aatgaacgaa gtaacccaat
     4021 tgaacctgtt gtagtagatg caggcgactt cttagaccct caaacagatg aaatgactca
     4081 atggtataaa gagtggaaaa gtataagaga taataatagt gataaaacga ttagtagatg
     4141 cccaatggtc atggatatga atcagggaat gtatgatgca gtagtacttg gaaatcatga
     4201 atttgtatct gaaaaagatg aattttggtc agatgaacgc cttttagatg ctgttataga
     4261 ggattttgaa caggtggcaa tttctgtgtt atcggcaaat atatataggc aatctggtaa
     4321 aaattatgtt aaaccatata ttataaaaga tgtggagacg agtgaaggta atgtaaaagt
     4381 aggaatattg ggacttacta taaaagaagt aggtaaaggt cttaaaaatg taaacttaca
     4441 agagcaattt caatataagg ataaattgta tgcaaatgat ttagtggaag atgcaaagaa
     4501 atgggtaaaa gttatgaaaa agaaaaaacc agatataata gttgcagttg tacattcagg
     4561 agaagaacca aaaaatccaa aacatccagg aaatagaata aaagaactag caactacagt
     4621 agatggtatt gatgcaattg ttgctagtca tactcatgaa aaaatagatg agcatgaata
     4681 taaaaataag tctggagaaa aagttatagt gacacaacca ggtgagcatg gtaaatatta
     4741 ttctaaaatt acctttaaag taaataaaga aaagggttcg tggactatta atgataaatt
     4801 cagtaaaaca attgaggttg aataacttta taaaatttat agataaagta aattatctga
     4861 tattggcatg atatataaga taaagtttct aatattagta taatgcataa tgtgaaatat
     4921 tttaataata agagaataaa caagacaaat aaaaatattt taacatgtaa gatatagtat
     4981 gaactattat actaatgctt actttataat ttgaacatgt tagaataagt cttatttgaa
     5041 aattttagtg tactagagta agtattattt tactagtaaa aaatattgag aactatatgt
     5101 agatttgctt aaaaaggaat ttacatatag ttcttttcgt ataataaata gtacaatctt
     5161 atatggtaaa gataaagtgt gatattaaat tttattatca tccaaaatct aaggaggagt
     5221 ctcttatgaa aataaaattt attatagtag catcaataat atttttaata gtattacttg
     5281 tggggtgtca aagtactaaa gacacagaaa tcaatgtact cgccacaagt gatttacatt
     5341 caattattcc agataattta atttcctatg tagaagagga gagaaaatat gatgagaatc
     5401 tacttatggt agatgcagga gatttttttg acatgcaaag tggtgagatg aataagtggt
     5461 ttactggtca aaaattagta agatttaaag atgggatacc agagtacaaa aaaatagctg
     5521 aaccacgtga aggagaagtt ccattggcta aaaaaatggc aaagctgaag tatgatgcag
     5581 ttacatttgg gaatcatgaa tttgtatcta atgacaagca gagccttgat aaattggttt
     5641 ctgattttaa aaataacaat ataccattag tatcagcaaa cgtatatgaa caatctggag
     5701 aaaactacgt aaagccatat gtaatgaaaa atataaatac tgacaaggga actgtaaagg
     5761 ttggtatact tggtctgact ataaaagaag taggggaacg ttcaaggttt aaaagttttg
     5821 aacaagataa aaaggctaga gaacttgggg aacaacctca atacaaaggg aaattatatg
     5881 caaatgattt agtagaagat gcaaataagt gggtaaatgt tatggaaaaa aaagaaaagc
     5941 cagatataat agttgccatt gtacattcag gtgaagagcc aaaaaatcct aaaaatccag
     6001 gaaatagaat aaaagaacta gcaacaactg tagagggaat agatgctatt gtagcaggtc
     6061 atacacatga aaaaatagaa cagcatacat ataaaaataa ttctggtgaa gaagtaatag
     6121 taacacagcc tggagctcat ggtaatagta tatcaaagat taattttaag ttggataaga
     6181 agaatgataa gtggtttata aaagacaaat atagtgaatt aaaggttttt ggaaaggaag
     6241 taaatataat tacaacttct ggtctgaatc caaaattttc agatgaaatg gcagttaatt
     6301 tgtttaatga aagagataga gatgttcaac ctatctttat agatactgga gattttttaa
     6361 atactaatac aaaagaaatg actaagtggg ctaaagagtg gcaatacaat gaaaataaag
     6421 gcatctataa aaaaataaat gaatggccaa ttgtatatct tggttatgat gctgtagtac
     6481 ttggtagcca tgaatttaca gaggataaag agacttttga ggaaaaaaaa tctacattgg
     6541 attatattat agaaaacttt gaagaaatga agataccagt attatcagct aatatatatg
     6601 atgaatctgg agaaaattat gtaaaacctt atataattca taatgtagaa actagggaag
     6661 gaaatataaa ggttggagta ttaggtctta ctactactga taaggatgaa gaagacttaa
     6721 gtaactcaag cttaagcaaa gactcaaaga cttcgaaaat tcctgaagaa acaggaaagt
     6781 tatatactaa taatctagta aaagatgcaa gcgaatgggt aaaagttatg caaaaggaaa
     6841 gtcctgatgt gattgttgca gttgtacatt cagataataa tagtactcta aaaaatccaa
     6901 gtagtgaagt caaaaaactt gcaatgtcag tagatggaat agatgctatt gttgtaggtc
     6961 atacgaaaaa taaggtagaa gaacatattt acaaaaataa gtctggggat gaggttatag
     7021 taacacaatc tggagaagat tgttattcaa aaataagtct tgaactaaga aaagaaaatg
     7081 gcaagtggaa tatcataaac aaatatagta aagcaataaa aatgaagtga atttattgat
     7141 atataaacca t
//
LOCUS       DAYAKB010000132         7078 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.133, whole genome shotgun sequence.
ACCESSION   DAYAKB010000132 DAYAKB010000000
VERSION     DAYAKB010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.133"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            312..1472
                     /locus_tag="ACGI3L_003547"
     CDS             312..1472
                     /locus_tag="ACGI3L_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFG9199226.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1814..1975
                     /locus_tag="ACGI3L_003548"
     CDS             1814..1975
                     /locus_tag="ACGI3L_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199227.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2168..2797
                     /locus_tag="ACGI3L_003549"
     CDS             2168..2797
                     /locus_tag="ACGI3L_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFG9199228.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            3036..4295
                     /locus_tag="ACGI3L_003550"
     CDS             3036..4295
                     /locus_tag="ACGI3L_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HFG9199229.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4566..5549
                     /locus_tag="ACGI3L_003551"
     CDS             4566..5549
                     /locus_tag="ACGI3L_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HFG9199230.1"
                     /translation="MTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIKVIKH
                     NNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGIGLDE
                     LILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDFGITK
                     ANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNSEEKM
                     LQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKAYIEV
                     EDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5795..6862
                     /locus_tag="ACGI3L_003552"
     CDS             5795..6862
                     /locus_tag="ACGI3L_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HFG9199231.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFAEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
BASE COUNT         2823 a          688 c         1200 g         2367 t
ORIGIN      
        1 tatttaataa ttaataaaaa taaatacaaa acaaaataaa taaataataa aatatttagt
       61 ttaattatct ttacaaataa aaattttagt aataaaataa ttgttgaaaa agattttaaa
      121 ttcagattat tcatttctaa agtaattaat gtgcaaatct ttattaatat atgtcaatag
      181 ttaggtatat atgtatttaa ttagcatgat atagataaaa gtatttattt taattgtcta
      241 ttatctgaaa aagtctttac ttagaaatca taaaaatcaa attaattagg aaaagaaagg
      301 gtgtgtataa tgtgattgag actggatttg tatattgtag tttcttggtt gtattcgtag
      361 gtgtaatttt ttttatggtt gataaattga aatggaaggt atttgatgtt attaatccaa
      421 tgcttttaat atacttaggt tcagctatac ttggatcatt tggtttattt gcacagaatg
      481 aagatgttgg aacgtatcaa aacataataa cagtgaactt ccttccatta atgttagtgt
      541 ttttgttaat tcaatgtgat ttaagaaaaa tattaaagat ggggcctaaa atgttattat
      601 catttttctg tgctacattt acatttatgc ttggatttgt tatagcattc ataattttta
      661 aaaattcaat gggtgcagat tcatggaaaa ttcttggggc agcatctggt tcatggatag
      721 gtggctcatc aaatatgatt gcagcagcta atgctctagg agttgcagaa gaaggactta
      781 gttatgcaat acttatgggt tctataggat atacagtatg gatgtctgtt tgtctaatgt
      841 ctgtgaaatt tggacctaaa tttaacaaat ggacaaagtg cgatacaagt tttatagatg
      901 aggttacatc aaaacttgaa aaagaaaata aagataatac agcacctacg tttgtagaac
      961 ttatgatttt actttctgtt gggtttggag ttgcgtcttt tgcacaaatt gtatccaaga
     1021 tacttccaac ttcaggtata cttaatgaaa ctatgtgggt agtacttgtt gcatctacag
     1081 tatcaatatt attgggtatg acaaaaatat caaagcttaa agggagtaca ctggtaggaa
     1141 atgtgtttat gtatttactc cttgcagcta caggtagtaa agcaaatttc tttggattgt
     1201 cagaagcacc tgtttacata atgtttggat tggtagtagt ccttgtacat gctatttcat
     1261 ttatagggct tgctaaacta tttaaacttg atttatttac ttgtgaagta ggaagtatag
     1321 ctaatatagg aggagtaact acagctccaa tgattgctgg ggttcacaat cctgtattaa
     1381 taccagtagg tgtacttatg gggcttctag gaaatattat agggacttat tgtgctctta
     1441 tggtaactca aatattacat atgttagctt aataaaaata tggtataaaa ttaataattt
     1501 aaataagaaa agtcatttca atttaagcag aagcttttac tgaaatggct tttttgtttg
     1561 acaagataat ctatttcaag aagatgtttt gacatattta gtgtataata ttgtaaaatt
     1621 tactaaaaac gagatatatt taatttttat attgaatcga acgtctgtat gatgtataat
     1681 aaatatacag aacgaatgtt tgcagaacgg gtgttttttg aatttatttt aataatttat
     1741 gaatatatat cagaatgcat aaatatattt aaatataaag attaaaaaga atttaaagga
     1801 gtgttgataa cttatgataa ttccatcaag aagaatacaa gatataacat taacaaattt
     1861 aaaaaatggt gaagtaactt taattgaatt ggatgaaata tacaagaaga tgggattttt
     1921 atttgttgtt agtgaaggca aattgaaaaa gataaaaaag gagaatcatc attagaaatg
     1981 aatgaaataa taaatattat aatagtttat aaaacctaac ttatgtagaa tataaatact
     2041 taagttaggt ttttttgtga taaagtttat aagtactcaa ttttataaga taaataatgg
     2101 tcttaagtga aaagtaaata agtttaaatt ttagtaagta ttatattgca taagaggtga
     2161 tattattatg aaaatagtaa cctacaatat tcataaaggt atggattcaa ataatagatt
     2221 aactctaact aaaatggggt tatatttaaa acaattggat tgtgatgtaa tttgtttgca
     2281 agaagtatta tatcctcaat ttttagcttt aaaagctgtt ttaaatatgg atggtgtctt
     2341 tgcgacaaat gtaaaaaaag taaatatgat atatggtatt tgtacattta caacatctaa
     2401 aatgttaaac agtaatcatt ttttcttaac tagcaaaaaa gaacaacggg gagctctttg
     2461 tataactata gatgcatatg gaagaattat aaatgtaata aatactcact tgggacttga
     2521 taggcaggag agagcaaaac aattagacga aataatagac tataggaaca gattagtggg
     2581 gatagttatt ttatgtggtg attttaatga gaaaaatgtc tttttaagta tgtttaatga
     2641 tatggctatt tcactaaaca agtcttactt accaacattt gaaaaatcaa actctagaat
     2701 agattacatt tttgttaata aaaatactga actaaaagga tacacagtag aaaaaattta
     2761 cctgtcagac cattatcctg taataggtta catttaaatt tcaatataaa tgaaattagt
     2821 tgttataaaa taaacaattt tttgttaaga aatagtaaaa gaaatataat aaaaaatatc
     2881 aaaaataaaa ctaattataa gacataaatt tacaataaag ttacatttga ttaaattcct
     2941 tgtttaacaa aagctattca aatataatct aaggtagttt tgaaatggga actctattat
     3001 gcaaatttaa gctagtgtta aaatgaggtg aagttatggg cagaagaaca acaagagttt
     3061 caagattagg taaagaaaaa aaacgaagtg ttttaattgt attggcagct ttagttctaa
     3121 taatgggtgg atttacttat ttttttaaca gtaaatttct gtacaatggg aaaatcgcta
     3181 aaaatgtata tatagaagga gtaaatgtat ctgatatgac taaagcagag gcattaaaag
     3241 ctataacaga taagtatact ccagaagatt taaatcttgc ttatgatggg aaaaaatata
     3301 caatatcacc aaaagatatt gatttaaaat atgatacaga agatgttgta aaagatgctt
     3361 atgaaagtac aaaaaaaggg tcctattttc aaaacttaaa aaaatatatt gatataagag
     3421 tgaataaggc aaatatgaag ataaaagctg aatatgatga ggcaaaactt agttccaaag
     3481 tgtcttctat agcagatagt ataaatgtta agatgaaaaa tgcttctatt agtgttggaa
     3541 gtggtggact aagttataca gactctgttg taggtagaga atttgatttg gcagcaaata
     3601 aagagtctat atataatatg ataaaaaata aagagcataa aactttagaa cttaaagtaa
     3661 atcttcaaaa accagatata acaactgaac aagtaaaaac tgtaaattct gttataggtc
     3721 aatattcaac tacttattca caagctgtag agggtaggtc atataatgta ggattatcag
     3781 caagaaaaac tagtgatgta ttattaatgc caggtgaaga attttcatac aataaactta
     3841 caggacctag taataaagca aatggttaca aagatgcacc tgttatagtt tatggtaagc
     3901 tagaacaatc agcaggagga ggtgtttgtc aaacatcttc aacagtttat aatgcggctc
     3961 ttctttcggg tatggagata actcaagtta caaatcattc atctgcatct acttatgtgc
     4021 ctaaagggag agatgctact gtgagcgatg gaggattaaa cttaaagttt aaaaatccat
     4081 ataagcatcc tgtatatatt aaaaattatg caggtggagg aagtgtatca tcagtaatct
     4141 atggtaattc tggtgacaaa ccaaatatat ctatagaggt aaaacaaact ggtcagaata
     4201 aatattctac atatcgaata tttaaagatt caagtggaaa ggtcataaaa aaagaacata
     4261 tatcaaatag ttcttataaa gaattaaaaa aatagataat tttttagaga aatatttgta
     4321 atataaaagg gagtgtctca aaatgaactt tttagtttat gagacactct ttttctgtga
     4381 aatcaaatat attttcatca tttcaacaat acaaaagaag cgtatctcta ttttgagaca
     4441 gccttttttg taaaaattaa cactattagt tcttgtttta atattacaat cattaatata
     4501 tagaaaatat tcctatatat tggtataatt gtaaatagat ttagttatat aaaatgtatg
     4561 aggaggtgac atggttgaat tttataggca atagatatga ggtagtaaat tctgacgacg
     4621 ttttagaaat taacaaaatc tataaagcta gagatgtttt ttacaggaaa aatgtgttaa
     4681 taaaagttat aaagcacaat aattatatct gtgaagattt tgtttcaaat ttaattgatg
     4741 aaagtactgc tttagatgag ataaactctc cttatatact aaaaataata gatgttggga
     4801 ttcactgtac agaagaaaca acattatatt atgttgtaag tgaagacttt aatggtatcg
     4861 gactagatga attaattcta ggtaattatc ttcatttaga agcaattgta aacataatga
     4921 tacaagtttt aaaagcttta gaaatgatac ataggaatca ttcatatcat ggtagtttaa
     4981 aatcgagtag tataatagta gatacagaat acaatataaa aatttgtgat tttggaatta
     5041 caaaagcaaa taatggggtt aatacaagaa gctatggaaa caggagatat ttatgcccac
     5101 atcaactatg tataaattat actgataaag aaagtgattt ttttgcaaca ggtcttattc
     5161 tatttgaatc tatatttaaa aaattgcctt ttggagaatc aaattcagaa gaaaaaatgc
     5221 tacaatctat tgataaggga ttagattgga atagtataaa agcaattaat ggaaatactg
     5281 aacttataaa tgttataaaa aggcttcttg gaagaaataa taagtatact agagccaatg
     5341 atattattat tgatttaagt aaagtaatgt atgaaaaagc atatatagaa gttgaagatg
     5401 agaaagaaga agagcagaaa caagacaaag ttatacaagt taaaaaagaa tataaaagta
     5461 aaatgagaaa aaaattacat aaaaaacttg ttgttgccgg tctagctata gtcatgattt
     5521 caatgattat tattagttcc ataatataaa aattgtatat taagtatttt aaaatcaatg
     5581 tctataaagg atatacatag aaattttagt gtagtcttaa attatgaaag gaagtggtta
     5641 ttatgttaac aaaaaataat gaggtattaa acgtctagga gtattttaac aaatagccac
     5701 ctgcttttac agtttagaat aaaaaagctg tggctaaagg tcacagcttt ttgctacttt
     5761 ttaaaggcag gagaatatta aaaaggagca aattatgagc aatataaaaa taatagcaag
     5821 taataaatgt tggattgaag atatagcaag gaaacaactt gaagatattt caaagttaaa
     5881 tggaatttta agagtagtag gattacctga cttacatgca ggtaaaatac ctgtaggttt
     5941 agcagttgag actaaaaata ttatttatcc acatataatt ggaaatgata taggatgcgg
     6001 aatgacttta tttaaaactg gggttctaaa aaagaaattt aaaaaagaca aatggattaa
     6061 gtcacttagt aagattaaag atttgtctga tatagaaata aaaaacacat ataaagaaga
     6121 atgtccaatt ttaaatttag gaactatagg gagtggaaat cattttgcag aaattcaatg
     6181 tataagtgaa atttataata aagaacaatt tgaacaatta aaattttcat ctgatgatat
     6241 tatgatgtta gttcactgtg ggtcaagaaa ttatggagaa gatattttaa aaaaatttta
     6301 tgataaagat ggacttgaag ttgaaagtga gaaagctata gattatatta aaaaacatga
     6361 taatgcttta atgtgggcag agcgtaatcg tgaagctatc agtaaaaaaa ttatgcagtc
     6421 aataggtaca tctggagatg ttgaaacaat attctctata aatcataatt ttatagagaa
     6481 aagggaagat aaatttatac atagaaaagg tgctgtttca agtgaaagag gagctgtgat
     6541 tataccaggt tcaagaggca gtctatcata tatagttatg cctactgaaa atacagagat
     6601 atctttatat tctctatcac atggagcagg tagaaaatgg tctcgttcag tttgtaaatc
     6661 tcgccttaaa agtaagtata gtaaagatac tataaaacaa actaaattta aaagtcagat
     6721 tatatgtaat gatgtaaatt tattatttca agaagctcca gaggcatata agaatataga
     6781 gcagattatt gaaagtttga tagaatatga acttattcaa gtagtggcaa ctatgaagcc
     6841 attgattact tataaaggat aatttttaaa gttaaaaaag attaaaatta tattataaat
     6901 agctaatttt atggaacatt taaaagtgtt ttattattag ctattttttt attttgtaga
     6961 gacgataatt tatagagcta aattctttga tatataatga ttacaaagtt agactgtatt
     7021 ggaaactgca catacatgaa ttgatgacaa tataagtgat tcccaaatat aaatgaaa
//
LOCUS       DAYAKB010000133         6771 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.134, whole genome shotgun sequence.
ACCESSION   DAYAKB010000133 DAYAKB010000000
VERSION     DAYAKB010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.134"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..889
                     /locus_tag="ACGI3L_003553"
     CDS             <1..889
                     /locus_tag="ACGI3L_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9199232.1"
                     /translation="NHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGIILDNGD
                     KILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKWIKDLQG
                     ISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVELNIDFL
                     PNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSKADEIRI
                     IEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVIDIDAET
                     GGYNLQIAFSTGYLAGISV"
     gene            935..1585
                     /gene="cmk"
                     /locus_tag="ACGI3L_003554"
     CDS             935..1585
                     /gene="cmk"
                     /locus_tag="ACGI3L_003554"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFG9199233.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            1636..2232
                     /locus_tag="ACGI3L_003555"
     CDS             1636..2232
                     /locus_tag="ACGI3L_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFG9199234.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            2245..3084
                     /locus_tag="ACGI3L_003556"
     CDS             2245..3084
                     /locus_tag="ACGI3L_003556"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HFG9199235.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            3329..4483
                     /locus_tag="ACGI3L_003557"
     CDS             3329..4483
                     /locus_tag="ACGI3L_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese transporter"
                     /protein_id="HFG9199236.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            4789..6486
                     /gene="ade"
                     /locus_tag="ACGI3L_003558"
     CDS             4789..6486
                     /gene="ade"
                     /locus_tag="ACGI3L_003558"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFG9199237.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMEVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         2731 a          681 c         1190 g         2169 t
ORIGIN      
        1 caatcacaat gtaaagataa tgtataataa gaaagttata gatattataa ctgaagaaat
       61 tgctctaaaa gatgattcta ataaggacaa gtcaaagtat ctaataaaag ggattatttt
      121 agataatgga gataaaatac taggagacaa ggttattata tcaactggag gagtgagtta
      181 ttcaaagacg ggttcagatg gttcaatgta taagattctt aaaaagcatg gacatacatt
      241 aaacaaacta tatcctgctt tagttccact tacaatagag gaaaaatgga ttaaagattt
      301 acaaggaata tccatgaaga atgtggaaat atcttgtaag attaagaaaa ggaaaatatc
      361 aaaatctgga gacatgctat ttgcccattt tgggataaca ggaccttgtg ttcttataat
      421 gtcttcttat attaacaaga ttattgaaaa ggaaaaggta gaattaaata tagatttctt
      481 accaaattta agtactgatg aaatctctag tataatcaga gcatttccaa ataaaaatgt
      541 tctaaataat cttaagcaaa tactacctca aaatttctta aaagagattt tttctctatt
      601 atctttagtt gataaaaagg caagtgattt gtctaaggca gatgaaatta gaattattga
      661 gtatataaaa aatatgaagc taacttgtaa tgggactaca ggtataaaca ctggtatggt
      721 tacttctggt ggtatttcag ttaaagaaat taattcttct actatggaat ctaaattagt
      781 taagaactta ttttttacag gtgaagtaat tgatatagat gcagaaactg gtggatataa
      841 tttacaaata gcattttcaa ctggatatct tgcgggtata agtgtataaa tataattttt
      901 taataattaa atatgaataa atagaggtgt atatatgggt aatttagtta tagctgtaga
      961 tggtccagca ggagctggaa aaagtacaat agccaagata gtagcaaaaa agctaaatat
     1021 aaattatata gatacaggtg ctatgtacag agcagttact tataagtgtt taaaaagtgg
     1081 tattgatgtc aataatgaaa aagaagttat tcaaatagct gaaaattcgg atatagattt
     1141 taaagataac aatatatatt tggacaaaga agttataaat gaagaaataa gaacaataga
     1201 agtaagcaat aatgtttcta atgtagcaaa aataaaagaa gtaagacagt tgatggttga
     1261 agttcaacga aaaataggaa tgaaaaattc agtaatacta gatggtagag atataggttc
     1321 atatgttttc ccagatgcag attacaaatt ctttttagta gctactccag aagaaagagg
     1381 aaatagacgc tataaagaac tttgtaataa aggatataat actactttag aagaagtaat
     1441 tgaggatata ataagacgag atgaaattga ttcaaataga gaatttgcac cattggtaaa
     1501 agctaatgat gcactagaaa tagatactac aggaaaaact atagaagaag ttgtagaaga
     1561 agttgtatct aaaataaatc tttagttttt tatgcatcat aatgaaaata aatgtagtgt
     1621 tgaagggaga taaacgtgaa tttttataga tttgtaataa atatttttaa gggtttttct
     1681 aaaatatttt ttaaatatga agttataggt gcagagaata ttccagatag aggaaatata
     1741 gtaatagcat caaatcataa atcgaatctt gaccctatat tcttggctgc tgccatagaa
     1801 aatagagaaa tagctgcaat tgcaaagaaa gaattgttta aagtaaaacc attgggattt
     1861 atattaaaaa aattgcatgt tatgcctata aatagagaaa aaccagatgt atctacaata
     1921 aaaactattt taaggtcagt tagagacggt tatgtattag gaatatttcc agagggtact
     1981 agaataaaag gagattcttt tggtaaggct aaggcaggtc tttctgtatt tacaataaaa
     2041 agtaaatcta aagttgttcc agtatcaata atatctaaat ataaactttt tagtaaagta
     2101 attgtatata ttggagaacc aatatcattt gaagaacatt ttaaggaaaa attgagtaat
     2161 gatgaccatg aaaggatatc acaagagatt ttagaagtga taaaacaaaa ttactttaaa
     2221 tattcaaaat aagggggtaa agttatgaac ataaaaatag caaaaaatgc tggcttttgt
     2281 tttggagtaa aaagagcaat gaaaatggca tgggatgaag ttgaaaaaaa tgattctggc
     2341 atatatgctt taggtcctct tattcataac aagcaagcag tagcaaaata tgaagaaaaa
     2401 ggtcttaaga ctgtgaatga aattgataca ataccaaatc atgaaaatat gataataagg
     2461 tctcatggag ttcctgaaaa tatatataag gaagccaaag ataaaaaatt aaaaattgtg
     2521 gatactacat gtccatttgt aaagaaaata catacagtag taagtgaata tcataataaa
     2581 ggctatgaaa taatagttat tggagatatg aagcatccag aagttatagg tataaatgga
     2641 tggtgtgaaa attcagctat aataataaag accttagaac aaatggaaaa tatggaattt
     2701 gataactcca aaagatattg tcttgttgca cagactacaa taaatccaga gttgtatata
     2761 agtatagtta ataaactatc agataaatta gaagaaatag tatttaatga tacaatttgt
     2821 tcagctacaa aaacaagaca agaatcagct aaagagttag ctaaagaagt tgattgtatg
     2881 atagttatag gaggtaaaca cagttcaaat actcaaaagt tagtaaaggt ttgtgaagac
     2941 ttagtaccaa cttttgcaat agagactaaa gatgaattgg atgtaaatac gcttaaaaaa
     3001 tataaaaatt tgggtattac agcaggggca tctacaccta attggataat agaagaagtt
     3061 gtaacattcc ttgaaaattt ataatttgat aggtaataaa aataggtgga cattgttata
     3121 atttatcata atatccacct ttgatttcat attacatgtg gtaaatagat aacctaatat
     3181 caaaaagtgt gtatcttaag atgaaaaact aagagtataa gatgcgcact ttttaatatt
     3241 agaaattcaa aagaaatatt gatattgatt atcaatagaa aatagaatat aatataattg
     3301 ttgcaaaatt agtctaggag gtaaattaat ggaaatgttg atatccgctt ctgaagaggc
     3361 gtttttacat gtaggttcta tgattggatt ttttattttg ttatttggat atattaatta
     3421 taaaactagt ggaaatttta ctaatatcat atcaaaaaac agaaaatttc aacccttaat
     3481 aggtgcttta attggagcta taccaggttg tggcggaagt ttggcaataa tgccattgta
     3541 tataaatgga aaattaagct ttggagcaat aattgcaagt ttaatagcta gtatgggaga
     3601 tgcagcattt gtacttattt catcaaatat taaaatgtat ttttttgtca ctatagttag
     3661 tacaattaca ggaataataa ctggacaatt agtggattac tttaaactag aagaaaaatt
     3721 agggttaaaa aaccgtagaa aatcagataa atatgatata agtaaaaata accctaaaga
     3781 aaataaagaa caacataatc atgatgaaat aattttagac actctagcta aatctcatgg
     3841 aaatacaaat agacttgcat ttataataac acatggaaag ggatataaaa tttatatagg
     3901 aattatagta atcggtttta tatttatgtc acttgctcac tctggactta atcttcctat
     3961 aattgagaag ttacattcat tggaagaagt aatagcagtg attggaatat tattttcaat
     4021 aatttatatg tggtgtttta aaaaggtatt taaaaattct aatcaaaaag aggaagaaaa
     4081 taaaaagatt tctttgcgag aaatgcttat ccattctgtt ggagaaatat catttgtaat
     4141 tacatggatt tttattgcat atcttattta cgatttgata atattaattt taggtggaga
     4201 tgaatactta gttaaattag tattatcaac aggtgtaata agtgtattta taggtgcagg
     4261 tcttggactt attccaggtt gtgggataca aattgtgctt atgtcatttt atttgaaggg
     4321 aactatacca cttggtgcag tgatagccaa ctctatttct caagatggag atgcactttt
     4381 cccactttta gcaatggata aaaaatcttc tttatgggct atgattatta ctactatacc
     4441 agcaatactt gtaggtatga tagtttatgc atttttaggt taaatataat tatgaataaa
     4501 gaagtattaa aaaaataata aagcacataa atttatttat aagaatagtg aagattaaat
     4561 ataaaaataa aaaattcaat atgaattaaa ttattgctta aatattaatg agaacatggg
     4621 agataatatt attcctcatg ttctctctat ttaattaaag gaattatgga acaaatttca
     4681 agtgatactt tctatcaaaa ctcatatata atatatatta ataaattaaa ctataatacg
     4741 taatacagtc agtatattga tataaaaaac ttaggaggag ttgtaaaaat gggtaattta
     4801 aaaagacagt gtgatgtttc aagtggaaga gaaaaagctg acattgtact aaaaaatggg
     4861 acaatcataa atgtatttac agaagagtta ataacaggag atgtagcaat agtaggagac
     4921 actattgttg gaattggcga ttacaagggc aatgtagaaa ttgattgtag taacaaatat
     4981 atatcacctg gctttattga tgcacatatg catattgaat ctacaatggt aatgccaatt
     5041 gaattatcga aaaaattatt aaaatcaggt acgacaacta tcatagccga cccacatgag
     5101 ttggtcaatg taaaaggagt tagtgcaata gattttttat tagaatcgac aaaagatata
     5161 ccacttaatg tatatattat ggtgccttca tccgtacctg caacaagttt tgaaactaat
     5221 ggagttggta aatttagtgc aaaagacatg gagagttatg taaataatcc tagaatttta
     5281 ggtttaggag aggtaatgtg ttttaatgat gttataaatt ctgaaaatga aatcttggat
     5341 aaactagagc tttttaaaaa taaagttgta gatggacatg cacctaatat aaatggtaaa
     5401 tcacttcaga catatgtatg tgcaggaata gaaaatgacc atgaatgtat aacttttgat
     5461 gaagtatatg aaaaattgag agcaggatta aaaattttaa taagagaagg aagcgcagca
     5521 aaaaatttaa agtctatagt aagtggtatg ctaaagcata acttgccaat tgaagaattt
     5581 atgttttgca cagatgataa gcacttagat gatatagaaa aacaaggtca cataagatgg
     5641 aatataaaat gtgcgattga tttaggtatg gaacctgtta gggctataaa agttgcaact
     5701 tataattctg caaaagcata tgggttaagg aaaattggag caataggtgc gggttataag
     5761 gcagatattg ttgtattgaa tgatttagac aaaatggaag tggatagtgt atataaagat
     5821 ggtaatttgg taaacgaaga gatgttttct aattacaatt atgagattaa agataaagaa
     5881 ttgcttaata cagtcaagtt taaatatatt aataaagaaa aaatacagtt aaaagtaagt
     5941 gaaaaaaatt atgtaatgga gattgtacct tatcaaattt tgacaaataa ggtatatgaa
     6001 tctttaccat gtgcagatgg atattttgtt ccaaataaag agtattcaaa actttgtgtt
     6061 gttgagagac atagaatgac tggaaatgta gcaattgctc cactaaaagg atttggcata
     6121 aaaaatggag caattgctac tactgtggcc catgattctc ataatattat agttgcaggg
     6181 gataatgatg atgatattct agtagctata aattacttaa aggaaataca aggtggttat
     6241 gtaattgtat caaatggaaa agttcttgca cacctaagtc ttcaagtagc tggattaatt
     6301 agtactttta cagctgaaga agtacaagaa attactgata atatgttgga gatagcaaga
     6361 aaaatggaag ttccagagta tgtagaccct tttattacac tttcttttat ggcacttcca
     6421 gttgttccac aaataagact tacagattta ggtctatttg atgttgagga atttaaattt
     6481 atatagatag tataaaagta ataataaatg aggctttctc aaaatagaga taagtctctt
     6541 tttattgttg aaatgatgaa aatatatttg atttcataca aaaaagagca tctcatgaac
     6601 taaaaatttt atttttagat atccttattt taattaatct atcatttaac attgttttaa
     6661 gcatagatat cttaataaaa ctattttcag tctattttaa catataaata catgaaaatt
     6721 atatatttat gaaactttat acataaaaaa taaaatattt tatttatata t
//
LOCUS       DAYAKB010000134         6746 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.135, whole genome shotgun sequence.
ACCESSION   DAYAKB010000134 DAYAKB010000000
VERSION     DAYAKB010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.135"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            170..919
                     /locus_tag="ACGI3L_003559"
     CDS             170..919
                     /locus_tag="ACGI3L_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199238.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            932..2959
                     /locus_tag="ACGI3L_003560"
     CDS             932..2959
                     /locus_tag="ACGI3L_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9199239.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTRILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYTNIQIKKIIKKQVLPFFNIPFLLGIVDCIFAT
                     LVYKTALMQNLLGNSLSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKK"
     gene            3103..4686
                     /locus_tag="ACGI3L_003561"
     CDS             3103..4686
                     /locus_tag="ACGI3L_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9199240.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            4658..5278
                     /locus_tag="ACGI3L_003562"
     CDS             4658..5278
                     /locus_tag="ACGI3L_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9199241.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(5467..6393)
                     /locus_tag="ACGI3L_003563"
     CDS             complement(5467..6393)
                     /locus_tag="ACGI3L_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HFG9199242.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
BASE COUNT         2424 a          925 c          866 g         2531 t
ORIGIN      
        1 tcttttaaat taaaatcttg tccatcatcc caaacctaat aaagttagat tttaaacaat
       61 atattgtgat ataagtaatt tgtgtagaat tattgcgtga tttactcatg aagaaacaat
      121 aaggttaata tataatttga ctatattaag acgaaaggag acatatacaa tgaatacaat
      181 attaaaagta aataacataa ctaaaactta taataaaggg caacagccga gtttagataa
      241 ggtatccttt aatgtatcag aaggtgaatt tataggtata atgggagctt ctggctctgg
      301 gaaaacaact ctacttaatg tattatctac aattgataaa ccaacaagtg gagatatttt
      361 cataaataat ataaatttga aatcgcttaa tgacacttgt gctgctgatt ttcgtaagga
      421 taatttaggc tttatctttc aagagtattt tttactagat agtcttacaa ttttcgagaa
      481 tatttcagta cctcttacac ttcagaaact caatccagat aaaatagaaa acatggtaaa
      541 gagtctagct gaacgatttg gcatagcttc tcaattaaat aaatacccaa atgaattatc
      601 tggtgggcaa agacagagag cttcagcagt tagagcaata gtaaaacatc ctagtattct
      661 ctttgcagat gaaccaacag gagctttgga ttctaattca gctactgaac tactccactc
      721 actacaggaa gcaaatgagg agttgaaaac aacaatttta atggtaacac atgatgccta
      781 tgtagcaagt tttgcaaata gaattttgat ttttaaagat ggtcatatca ttaaagaatt
      841 aaataaacaa cagaataata gacatacatt ttatgagttg attattcaag aaattgcaaa
      901 attggatact aaaagatagg aggataattt aatgaacatt ttttatacgg caataaagaa
      961 tcttaaaaaa aacttttcat tctattctct atatctactt tcagtctctt ttgttattac
     1021 tgtatttttc gcatttactt cattttctgt taataagata atgctagaaa aaatttcaac
     1081 tgatggtaga gttgaatcta tgtgtaatgt tatttcgata tttttgatgg catttgtcat
     1141 cttctatatg gcatactcaa atcgattctt cttgagacgt cgtacaaaag aattaggtat
     1201 atatgcttta cttggctatc gtaagtttac aatattatcg ctacttacct ttgaaaatgt
     1261 attaatttgt agtggagctt ttattattgg attggtatta ggagcattgg cacataaggg
     1321 tattgtcttt ggaattacag cactacttaa tttatcaatt gataattcac agataccatt
     1381 ttttaatata aatgcaataa ataaaacaat tatctttata gcattagttg ttttagtctt
     1441 agctgtatca aatggtaaat ttttttataa gactccactt gtaaaattga taagatatga
     1501 aaaaagtgca gaaaaaaaat taaagttcag aaaaattcca gcctttatgg ggtttattat
     1561 gattttaagc gggtattgtt tatcactaga tattcttcgt ggagctaaat cagtatgggt
     1621 aagtattgga ttttatcaaa tgggcttgat aactatgatt atcattgtaa ttggtacagt
     1681 tctctttatc aattcctttc ttccatatat tatgcaaaat agtaaaaaaa ataaacgtac
     1741 tttctacaca gatatgaaga taatagctat tccaaacttt atctatcgta tacgttcaaa
     1801 ctctaaaact ctaattatgc ttacattact ctctgctact actttgacag tttcaagtgt
     1861 tatggcactg tccttatact accctattgc atctgtttcg cgtattgcac cttcagagat
     1921 agaatttaga gtagaaaaaa ataaacaaat agaagatgta aaacaaattg tcagtcaata
     1981 tacgtctaat acagatgata ttatttttac acagacaaat atttataagg taaaatcttc
     2041 atcaaaagac cttccatttg aatatgaaat tggtacatct aagaataatt tatccaatag
     2101 tagttcttct aaagaagtta tttcaagaga atcaggattt gaatgtatat ctttttctga
     2161 ttattatact ttattaaagg cacaaaatcg aacaaagcta ctaaaacaac ttaccccttt
     2221 aagggataat gaatgtattt taatgaaata tcaaccaaat aatgatggat atagtgaaaa
     2281 tggaacgatt tatccattac ttgttaatgg taaagaaaca cctgtagctg taagggaaac
     2341 atcattaaac aatgctattt cttttgccaa tagcgttgga acacttatcg ttaatgatag
     2401 tatatatgag caaatagcac aaaataaatt accaatgaca agaattttaa gtattaatgg
     2461 taaatcaatt aaaaataatg aaaatttata tagtaatatt tcagattatt tagatggaag
     2521 cccttattta caaggatatt ctcacaggat aaatgattta ttatcaatta atagttctac
     2581 atttctgtta atcggatttc ttgtggtatt attctttatt gctgttggaa gtattttata
     2641 ctttaacaat atatcagcaa tttcagattc aacatctgat tataaaattt tacagaaaat
     2701 gggttatact aatatacaaa ttaaaaaaat tattaaaaaa caagtattgc cattttttaa
     2761 tattccgttt ttacttggta tagtggactg tatatttgct accttggttt ataagactgc
     2821 tttgatgcag aatttacttg gaaattcact ttcacaatac atacctgtga ttattgcaat
     2881 tttcttaact tctgtagtat atttgatata ttacatactt actattaaat cctgttgtaa
     2941 aattgtatta aaaaaataat atttgccaaa tcgtcaagct taaaggtgtg acgatttggt
     3001 atacttcatt tataagtatt tgatataatt taaaactata aattcttaag tttgatttag
     3061 tcataaaatt aatataatta actcataagg aggtgtataa gattgacaaa ttttaattta
     3121 aaaatactat ttttaggaaa ctacattcta tcacttctct tcatgggaat atctacaagc
     3181 actgaaactt atatgaatat tcaaagcatt attcccttaa taatttcaac attattactc
     3241 atagacatca catatataac ctcttgtaat gtccgagaaa ataacattat ttcattgttt
     3301 tgtggattac tagcactaga cagttggtat ttactcttat catttgtaac cacaccaata
     3361 ggcactatta tttttaaaat attaagcaca gttatagtgt atgtctctat taaatttata
     3421 tttttatttt tgtttcaagg tagtggatac aatttccgta agataacaga cattttattg
     3481 cttatcacct gcattggtgc aattgtagga gcatttattt ctaacagaac gtatgcttgt
     3541 atgtacggaa tacagtttgt tgttagtata ataagctttt tctatattat tttttatcat
     3601 ttgaaaaggg ttgtttttgt cataaaaagc gaaaaaaaac ctatatcgat ttcagtattt
     3661 ataacaatta taggattcct tacttattat ttttttacac taagaatatc aaatcatatt
     3721 ggtaattttg gaatctatct aactgtactg gtatttttta tgagtattca tggtattgca
     3781 cttaaagaaa atgatagttt tcctatttca acagttttta acataaaaca aagggctata
     3841 tttcttttta taagtatttt agtaattagc ttggtcgtac tatttgccaa tgggaatttt
     3901 tctataatat taatagctat aaatgtttta tttatgctca ttttcctctg taacattatt
     3961 ttggagttta accttagaga tgaaaaaaat aaagtagtta aaaatagcaa gtatactttt
     4021 gcattagaaa aattacaaca agaagaacaa ctaaaaacag agttttctaa ttttttacat
     4081 gatgacatat tacagaacct gctttcaata aaaaacatga tgagtaagtc atatcgccca
     4141 gatgttcaag atattatata tgaaacactt aacaatctaa atacatgtat aaggaagcaa
     4201 atgcaagact atcatcctgt tattttaaaa aatttaacag taaaagaaaa ttatcagaat
     4261 ttaattgaaa gtgtttcttc atcctttcca caaaaaaata tttgtgtttc atttaagtgt
     4321 tctgatactt tattcttagt tgaaccatat gatatattga tatatcgact gattaaagaa
     4381 ttattgacaa atgtgtataa acattcaaat ggtagccatg catggatagc tttagcacta
     4441 gaaaaaaata taataaaatt aaatattagt gataatggtg tggcaaatac atcttttaaa
     4501 acgcctttag atataactaa aattactttt gatacaataa aacacaaagg gattatatca
     4561 attaaagaac aagtagaaaa tctaggagga acgataagtg tttctgataa tatacctcat
     4621 ggagtttgtg tacagattac aatccctatg aaaggagatg gttcttataa atattttgtt
     4681 agttgatgac catatgcttt ttgctaaaag cttgtcaatt gcactagaag aatacaaaga
     4741 aatcgaacag ttttattcca cacaggacat ccataatctt tcagaaatga ttcaagataa
     4801 aaaaatagac attgtcttaa tggatataaa ccttagaggc ttaagtgaat gtgatggctt
     4861 aaaagtagct tataatttat tagagactaa ttcaactatt aaaataataa tcttgactgg
     4921 atacgacctc ccagtttata aacatgaggc taaaaaaata ggtatctatg gattcctcaa
     4981 taagaatatt agccctgata gtttaattga ttcattatta aaagtctatc aaggggtaac
     5041 ttgttttcca tctgaaaata ctgaagtaat tattgaagat ttaactacta tggagaaaag
     5101 aattttacag cttatctgta gtggtaaaaa aagaaaaata attgctgatg aattgtatat
     5161 aagtgaaaga acattatcaa atcatttaca acacatatat gacaagctag atgtttcatc
     5221 atcagttgag gctattacaa aagctattaa aatgggttat atttctccag tatattaaaa
     5281 aaagtgagtg tctcaaaata aatcttctaa ctcataaagc actctccttt gtattaaatc
     5341 aaatatattt tcatcattta aacaattaag aagaggcttc tctctatttt gagacaactc
     5401 cattttaata cactatttat atttatatat aaacatattt taaacaacta aaaagcaact
     5461 aatatctcaa tacatatctt cataacacat atcaccataa ttacaagcag ataaagaact
     5521 ctcctcattt aaatacgact caaattcata cccaaacaga attgttggtt ctatatatat
     5581 ttccatatct gtatatctcc atcttcttac ctttgcctct ataaccttgt aaaaatcttc
     5641 taaactatac ccttctttta atcttttatc tataagtgcc ttagttatac tcaaatcagc
     5701 tttaaaattt tttcctgatt cactatttaa ttttcttata ataatttcat gtatgctttc
     5761 tggatttttg taagtagaat cttcagtcaa atcttcatcc gaattttcaa aggtattttt
     5821 atttaaattc tttttattta aattattttt taataattct tttttctttg tctcattttc
     5881 tgtttcatac ccagtatgaa ttatcaaatc ataatctttg tctatactct cttgatttat
     5941 acggctgtat atgttggtat tactgttctt aaacaactca tttctatgtt tatatttcat
     6001 tgttttttgg ttattgttaa tagttgcatc aatgtatttc tctatatttt tgaaaatatc
     6061 accattcttt gttacaattt ctgcattact actttcagaa caaacataac tatatacaga
     6121 acaacaattt ccctttactc ccctacttat taatctcaat atacctaaat ctataaattc
     6181 atttacaagt ctacttattg tagatataga tacatcaagg tcagatgcag ctttccttac
     6241 tgtcatcata aattgtcctc ttggcagagt tccttttaat ctttgtatat tttcttttct
     6301 cattacatag tgattaaacc ttattctatt tacatctctt ttttcattaa aatataatac
     6361 tgctgaattt aattgataaa aactattact catattccca ctcctccaat ttaaatagat
     6421 aatttgttgt aaagttttta gatttttaaa taacttatta aatgattatt tttattaaaa
     6481 agtattcttt gatattttca ttttaaagtt ttaagtataa taagttaata gtgtagattt
     6541 aactttttta tttaaacaat aaacttaata ttatttttaa tataaaaatt ttattaaatt
     6601 tagtatgtaa ttttttaatc ttattttatt ccatctatac tcttatgcta agtaataact
     6661 ttgataatat ttccctaact tatgtttcaa ctggtttata ttgcaattta tttaattaca
     6721 gcttatttgc ataataattc gtccat
//
LOCUS       DAYAKB010000135         6458 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.136, whole genome shotgun sequence.
ACCESSION   DAYAKB010000135 DAYAKB010000000
VERSION     DAYAKB010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.136"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(370..777)
                     /locus_tag="ACGI3L_003564"
     CDS             complement(370..777)
                     /locus_tag="ACGI3L_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II flippase MurJ"
                     /protein_id="HFG9199243.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1251..2135)
                     /locus_tag="ACGI3L_003565"
     CDS             complement(1251..2135)
                     /locus_tag="ACGI3L_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9199244.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2426..2902)
                     /locus_tag="ACGI3L_003566"
     CDS             complement(2426..2902)
                     /locus_tag="ACGI3L_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HFG9199245.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3168..4343
                     /locus_tag="ACGI3L_003567"
     CDS             3168..4343
                     /locus_tag="ACGI3L_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HFG9199246.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4424..5227)
                     /gene="proC"
                     /locus_tag="ACGI3L_003568"
     CDS             complement(4424..5227)
                     /gene="proC"
                     /locus_tag="ACGI3L_003568"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFG9199247.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5267..5857)
                     /locus_tag="ACGI3L_003569"
     CDS             complement(5267..5857)
                     /locus_tag="ACGI3L_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9199248.1"
                     /translation="MVLNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLT
                     SVATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLK
                     EKTMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYN
                     SEKNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2131 a         1098 c          724 g         2505 t
ORIGIN      
        1 aagcacagac tatatcttat ccttcagcat tatccgttaa ggtctaccca cttccactac
       61 caatagcttg tagtgtactt ccctcaagag gaatagtcgt tgaagtttct cctattcgga
      121 gtttacctgc tgattgccca ttttaaagta cttaggattt aaccttatac catctaacca
      181 attttttcta ctttcgtaac tttcacactt aggtttattt catccttatg ttttagtttg
      241 attagcttta ggggtttcca gcaattcaag tagtattgga taggttctat cctatctcta
      301 catataggtt tccctatatg ctgactattt tagctactaa ctcatgacta aagtcacgag
      361 tgtgcgtagc tattttttaa tcaatatttt agtaaatttt acggtaagta aaaacctctc
      421 tccttcaaat cctatagcaa atatacttac aagttgcttt gagaaaataa ctcctaatat
      481 agctacaact atgcatatac caactattat atttaaaaca ttgtttaaaa actttagtgc
      541 ttgcttttca ccttgtttac tacttatatc ttgatacatt ggaataaaag tagtaactat
      601 agcagtacct attgctgcaa atataatatt tggtatattc atagctgtta aataactctc
      661 tgtatataag cctgtaccat aaattgatga taatactaat tctctaccca ttccaagaat
      721 cttagagatt atagtaacta tcatcaaata aaaagttgct ttagctacct tgctcatttt
      781 atcactccac ttctaacata cctcttttta atcaagtaaa atttagctca ttagatataa
      841 ttctatcaac taatttgcct tgcttagccc tatcaaaata taattaacac ctatttctta
      901 atatatcaca aactacatta ttcttcatat ttttttattt ctccaataag ttttacattt
      961 ttcctatata aattgtatag cttcaattat attcaaagaa atggagttgc tacccgataa
     1021 ctttaaaagt aaaaaacaga ttttattatc tttttaaact atattctaac atattttgtc
     1081 catattgaga aattttacta aactattatg tactttatta aataaataaa ataacagcac
     1141 acctataaaa tacaagtgtg ctgttcataa acagatttta taaaaaaata attcctaagt
     1201 agagattaac atgctttctc atactctcat atataatgtg tctaaaaata ttaataaaaa
     1261 tgctttaatt gttttaactt acttggatgt cttaattttc ttattgcttt agcttctatc
     1321 tgtcttattc gttctctggt aactccaaat acctttccaa tctgttctag tgttttaggg
     1381 tcatcatcat caattccaaa tctcattctt aaaacttgct gttcttgctc tccaagacct
     1441 gtaagtagtt cttctatctt ttcttttaaa ttatgctgtt caacttcgtg tattacaaca
     1501 tctttaaaat cagcatctga tggtataaat tcaactaaac tactatcctc atcttctttt
     1561 aatggagtat ccaaagatac aacattttta tctcttctta ataattccaa cactttgtca
     1621 acttctaagc cacatgcatc tgcaatctca tctatagttg gctctcttaa taatacattt
     1681 aaaagttctt gtttcttttt ctttacaaaa tttattctct gatgaagatg tataggtatc
     1741 ctaatagtat tttcgcaatc gtcgatatat cttgttatac tttgttttat ccaccaagtt
     1801 gcataagtgc taaatttgta tcctttttta taatcgtact tttctacagc ttttataagt
     1861 cctatatttc ctgcttgaat taaatccaac atatcaatac tatctctttt atatctcttt
     1921 gctatgctca ctaccaacct ataatttgaa tttataaatt tttcttttgc tactgaagat
     1981 gagttgatta tttccttagc cagctctacc tcttctcctg ctgacaacat tttgtattcc
     2041 tctatttcct ttaaatacat tttcatcgca ttcgatacat ttgatgaacc cacacaaata
     2101 taattttcat aattattttc ttttttagta tccataatca aaccccttct attcatagaa
     2161 tttgctaaaa caaaaataaa taatttaaac ctacataatc tacaattaca taatatccca
     2221 ttctttaaat gaattgtttt gtatattatg tatacaaatt tataaaaact atacctataa
     2281 tattattcta cttctaacag caatatcctc cttatatata taatttattt tattatatgt
     2341 tgttatattc ttagtttttt gaatgatata tgtctaaaaa aagactgttt actaaacagt
     2401 ctttttttat atatatgctc aatatttaat tttcatgatg atgattacat ccacatccac
     2461 aattttcatc atggtgatga tgttcttcta aatcttttac ctgttgttcc atttcatgaa
     2521 actcttttac cattatatca taagttggaa gagctgcctc agtatcgtat tcttcccctc
     2581 tccaatcagc gtacatcata gcatctccat tagttaaaac caatctacct gacatagtta
     2641 tattatccac ttcttctaaa aattctattt gtttttgtaa aacttctcct tctaactcca
     2701 catcttcatc taaacattgc actatcatta caggtgcata ataatcttct tcatctttaa
     2761 catttacaac aatatctaaa attccttctg caccttcttc aaattctgcc aactcaacat
     2821 ttgtatcaat catatcttga ggtactaata aatcttctat taaatatttt attactctat
     2881 cttttactaa ttcttttgac atttattttt ctccttccga ttctataaca ttatcataat
     2941 catttctata ttatagtata ctacattaat tgttttttca atctcttaca aaaattattt
     3001 tttattatct tccttatatt ccctttttta ttacaaagtt gtaatcgcat tgatttaaaa
     3061 aatagtttat atttagtata atagaaatgt agcacatatt tttattcaat atattaataa
     3121 aaaaatatat tgaaaatgta atgtatgtta aatctaggag gaatattatg aagtttaaaa
     3181 aacaaattag ttctattgtt gtgtctacta tgcttgtact tgggagtatg aacctttctt
     3241 atgcagacgg tacaaatgta gttacacttg gagctaactt atcagagtct caaaagcagc
     3301 aaatgcttaa ttactttgga gtaaaaaaag accaagtctt agttttagat gtaacaaatg
     3361 cagaagaaag acagtattta caaggtgttg caacagaggg tcaacttgga aaagttacta
     3421 tctcttgctc atacgttgaa cctactaaaa aaggaaatgg aattaatgtt aaaacagcaa
     3481 acttaacttg ggtaactagt tcaatgattg cttcaaccct tacaacagct ggtcttgaag
     3541 atgcaaatgt tattgctgct gctccatatc ctgtaagtgg tactggagca ttgacaggaa
     3601 tcatgaaagc atttgaggat gcttcaggaa agaaacttga tgaaactaag aaagaaattg
     3661 cttctgaaga attggtagtt acaggtgact taggagatga tatagggcaa gaaaaagcaa
     3721 caggtgtaat gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa gataccaatc
     3781 aaatagcaaa tacaataaat aatgttgtaa ataattacaa tattactatt acaccagaac
     3841 aaaaagaaca aattaaaggt gtaatgaaaa aaatagctga ccaaaattac gattacaata
     3901 gcatgaaaaa tacactagat aatgtatcag ataatgtaaa tgaacaatta aagaaattag
     3961 gtgaaagtgt taagggttct ggtatactag atactattgg tggatggttt agtggaatag
     4021 gagactggtt ctctggttta ttctcaggcg gagataaaaa agatttggga atcttaaata
     4081 atactaatga tgagtctctt ggctctgatg ctgtaataaa ttctacagaa ggtgttcaaa
     4141 taaatccaca aaataatact aattctaaca atgatagtga tacaaatagc tcaaaaaatg
     4201 atacttcaag taataatgaa aataacgata gttctcaaac aaatgaaaac aacacaacaa
     4261 ataattcaga aaatcaatca aataataatg actcagttgg tttctttgaa aaaataaaaa
     4321 attggctttc aggcttattt tagaaattaa acaaataaaa agaattgcct aaaatggaaa
     4381 ttttctataa aaggcaattc tctttattta caataaattt ttattactca ctcatttttt
     4441 tagatttttc tatacatgca catattgctt ttatcacaga agctctaaaa ccttcttctt
     4501 caagtacttt aactgcttct atagtagttc caccaggtga acataccata tcttttaatt
     4561 caccaggatg ttttcctgtc tcaagtacca tttttgcaga acccataaca gcctgtgatg
     4621 caaacttata tgcttgtggt cttggcattc ctgcaattac tgctgcatct gctatagctt
     4681 ctataaataa aaatacatat gctggtgcag aaccacttgc accaattaca gcttctataa
     4741 gatactctgg tactacctca gtatttccaa aagaattaaa tacttctgta actgcttcta
     4801 agtcttcttt gtttatattt ttatttatcg aaagagaaga catggcttca tttacaagag
     4861 ctggagtatt tggcatagtt ctaactattt ttttatcttc tcctataata gactctatat
     4921 cttttataga ttttcctgct gctattgtaa ctataatttt attgtcatct ataaagtctt
     4981 ttatctcttc caaaatatca tcatatatat ctggtttaac agctacaatt actatatcag
     5041 aggttctagt tacttccttc gagtcttttg tagtatttat tccaaaattt gcatctattc
     5101 tatcgagagt tccttgacta tatgctgatg ctataaccat attaggttca actaattttg
     5161 aatttactat tccccctatc atagcgcttg ccatatttcc tgcacctatg aatccaattt
     5221 ttttcacttt agtacctcct tattgactaa tagtaatcgt taaaatttaa gcttctttaa
     5281 ctgcatcaga tttttcaaat ggatttggta tacttactac caaaattttc actaccttat
     5341 tagtatagtt gacccaatta tgattgttct tttcactatt atagtgtatt gtgtctcctg
     5401 gatacatttc tatttgttca tctcccaaaa acactgtaag agtaccctct aatacataca
     5461 caaattcctc accttcatgt acgtaacaac aaatttcctc actactctta cttggaagaa
     5521 tttcaattaa tcttggtagc attgtttttt cctttaaact agatgataaa tgataatgta
     5581 taaatgttga gttttctaca tcaaatactt ctttttcata acttcttaat acagctcttt
     5641 tatgctcttt tggcttcata aaaaagtaag ttaattctac atctagtaca cttgctattt
     5701 ttcctaagga atctgttgcc acacttgtta atcctctttc aagttgtgat aaaaaaccaa
     5761 ttgacaagtt tgttttttca ctcatatcct tcagcgtcat ttgcttttga gttctgagtt
     5821 gctttatttt tgctcctatg tccttattca aaaccatcac ccctaaataa ttttaatttt
     5881 ttcataatat aaatacaaaa atataaatat aggtactgaa cccatcttta tttcatttaa
     5941 aaaaattttt ataagtatta ctataattta tcaatctttt tttgtctaca tttttacgat
     6001 tatttacgat ttatttttca catatgtata tttaatcttg ccaactaaag atacattttt
     6061 tataagcatt tactctttat ataataaaac ttaagttgtt catgtagtct tcttctggtt
     6121 taattattaa aatttcaaat tatattatta tttctacaca ttattacatc ctttagtaca
     6181 attataacat aattttacaa tttaatgata tctattcaat gtcttttttt actctacaac
     6241 atattttatt ttagagttta atactatata tattttttat atacagcctt gtcatttttt
     6301 agattgtcaa gagttattga agtattttat gtagatttag attttatttc ctaatttctc
     6361 atttaacaag aattgcttat gataaaaaat aatatcatct caataagatt cttgtaaata
     6421 tatctatatt ctaaatataa tttctttttt tgtcaaaa
//
LOCUS       DAYAKB010000136         6413 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.137, whole genome shotgun sequence.
ACCESSION   DAYAKB010000136 DAYAKB010000000
VERSION     DAYAKB010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6413
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.137"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            85..234
                     /locus_tag="ACGI3L_003570"
     CDS             85..234
                     /locus_tag="ACGI3L_003570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199249.1"
                     /translation="MFKNKMDKCTHVLTAYISSSYDYYNFLDTQLDDFILEYGENVVS
                     LVYTK"
     gene            367..567
                     /locus_tag="ACGI3L_003571"
     CDS             367..567
                     /locus_tag="ACGI3L_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199250.1"
                     /translation="MCFKTYVLKRVVNNNQLEITRSFDLDNLICTATEILKDNEIDLI
                     IIDEKNNVVWKNEKSTPQQENA"
     gene            777..1082
                     /locus_tag="ACGI3L_003572"
     CDS             777..1082
                     /locus_tag="ACGI3L_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199251.1"
                     /translation="MNVEQSKSKKVYLNIGEELSKKMTKSELNKFSQELANYLQYAGL
                     DKNMKIKLFQTILEMVARKKITLSSDSEFTEGILQSDEAEMTTNVGFIIEGLSYHND"
     gene            complement(1391..1870)
                     /locus_tag="ACGI3L_003573"
     CDS             complement(1391..1870)
                     /locus_tag="ACGI3L_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199252.1"
                     /translation="MDKMDKKEAKKFLKVIDMNIDKIEEEAIKAFKESCLIKETNDIK
                     IYIDIQGKVEAIAIQAYAKLLDDDKEINIFTSRQTGNNLDDMFGEIYYVNDYEEFENW
                     CENKCESLNWDSYKKFNKENFEEIAERNIDDSTSVFLEELREGIESCKQELQNIVEN"
     gene            complement(1893..2396)
                     /locus_tag="ACGI3L_003574"
     CDS             complement(1893..2396)
                     /locus_tag="ACGI3L_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199253.1"
                     /translation="MNIDFSTILDLKVNKENVKMIEKEINKINNDIFDISLKDCANGH
                     IGSVKETVGKSLNIETWGHGEINSKIGIRLRFNFYYSKGDKVDIENIENILIYVNSLC
                     SKNVESDLIANVRPKFYKLEEKYSTRIEKCEIRHEFIGINKQEIKEFLEYLTEIEKSE
                     RTVIYKK"
     gene            complement(2473..3306)
                     /locus_tag="ACGI3L_003575"
     CDS             complement(2473..3306)
                     /locus_tag="ACGI3L_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199254.1"
                     /translation="MKILFKEAHKMAREIKRKYSNVDYKVQFSLCLSFLNKKGDIKLK
                     ELKGSEKQIIWANDIRTDILNLTNELEKSKIERIKNEDYKIKDMSIEEMTERCKRKFE
                     RIREAISNIENAKFFIDNFRNVLKYNSLNQKAFHINQILKDSQFAKENRNWSFLQGET
                     QASYRLKKVKDYSISYEEAKKIAKEINFNDNWSNEIKENVLEIVEIFDDAVKQATSTE
                     YIEKAKKYIIETLIQKNAQFYRNGFADIKKKQIENYRKIESDERKIEIAYQVFRDGVE
                     C"
     gene            3485..3697
                     /locus_tag="ACGI3L_003576"
     CDS             3485..3697
                     /locus_tag="ACGI3L_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199255.1"
                     /translation="MTWKNEIKSILVKENISMNELNNLMNEHNNKNNTVENLRQKINN
                     ETMKYSEILTIANLIGYEVVWKKKEK"
     gene            complement(3743..4549)
                     /locus_tag="ACGI3L_003577"
     CDS             complement(3743..4549)
                     /locus_tag="ACGI3L_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9199256.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     IVYTGKVDKSNNYLAEQCKIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNDKLATVFENRGAKSDVRGLYWLKHTKAPAILIEVCFVDSKADTDYYIKNKNTV
                     AKLIAEGILNKNINNKENGEGKIMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIK
                     DYVPGQTQNLYVVGGGACEKISSMTKENYTMIKGNDRFDTLHKVLDFIDR"
     gene            complement(4549..4806)
                     /locus_tag="ACGI3L_003578"
     CDS             complement(4549..4806)
                     /locus_tag="ACGI3L_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9199257.1"
                     /translation="MDNLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYIPIILLVI
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGDK"
     gene            complement(4826..5056)
                     /locus_tag="ACGI3L_003579"
     CDS             complement(4826..5056)
                     /locus_tag="ACGI3L_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HFG9199258.1"
                     /translation="MNEELVKEKISTLETRVKEHGKQIDRIEIEQAKFAIQIQNLCSD
                     IKNLTGVLKWLVGVIITTLVGFFIFAIQKGIF"
     gene            complement(5097..5279)
                     /locus_tag="ACGI3L_003580"
     CDS             complement(5097..5279)
                     /locus_tag="ACGI3L_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199259.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRVFELDDVTNTEYRMAVEN
                     YIIEHSEVVEGAELTK"
     gene            complement(5279..5572)
                     /locus_tag="ACGI3L_003581"
     CDS             complement(5279..5572)
                     /locus_tag="ACGI3L_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199260.1"
                     /translation="MERGNRIICDQTGKILLQTGEATGDILEHDEITELHFVDIPYGS
                     IDYTRNRIIGINIETKEPILEEIPTFISDEEKRIQELENQILLNENEKVGGIL"
     gene            complement(5593..>6413)
                     /locus_tag="ACGI3L_003582"
     CDS             complement(5593..>6413)
                     /locus_tag="ACGI3L_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199261.1"
                     /translation="LTKIEYFIDDVLKETITTDLTTEKTINYTLEDNALHTLKIVVTD
                     SNNATAEKVLSISKNIMPLPEDVNLQDISSKLIEVNAGFKTGKTSIINTLALKNIEAN
                     LNNTLVELSEKIKTGFDSSDATAEQLQNQITNLNNQLSQRKRWAKGTYTFTQSDYENF
                     YSRYSSAENYAKSLTVPINLNFIPSLVIVEKLCFYGNGYTVNFYAINNLNQLASVGRV
                     PKSSGEYRFCAFMFVKTITSKEFSLYTYRDEYTDSSSVVYRCKVGESFTWYAYE"
BASE COUNT         2048 a          997 c          700 g         2668 t
ORIGIN      
        1 atcttatgag ttatgtcagc cagttgccaa agagatattg ttcttttgtt tttatgaaag
       61 ttttttaggg gtataataat ttatatgttt aaaaataaaa tggataaatg tacacatgta
      121 ttgactgctt atattagcag ttcgtatgat tattataatt ttttagatac acagttagat
      181 gattttatat tagagtacgg agaaaatgta gtgagtcttg tttacaccaa gtgatggtat
      241 tggtaagtaa gtataattag atagacattg atttctagag aacccttttt agttttatct
      301 acttttaaat attactatgt taaaaaatta attaaagtat ttttgtgaga aaggataata
      361 atataaatgt gctttaagac ttatgtactt aaaagagttg taaataacaa tcaactagag
      421 ataactcgta gtttcgactt agataatctc atttgtactg caacagagat tttaaaagat
      481 aatgagattg atttaataat tattgatgaa aaaaataatg ttgtttggaa aaatgaaaaa
      541 agcactcccc agcaagagaa tgcttagtta taactataga agtgtactac caatacactt
      601 ctatttttta ttatatcatt aattttgttc ataaaaaaga gctatttaaa tcaattttaa
      661 ggtgtgttga gtaatgttat tgatgtttta tatacttaaa caaaaatatt tatatttgaa
      721 gtattagcat ttttaaaata taattgaatt ataacttaaa aaaggggttg aaaaaaatga
      781 atgttgaaca atctaaatct aaaaaagttt atctaaatat tggagaagaa ttatctaaaa
      841 aaatgactaa atctgaatta aataagtttt cgcaggagct agcaaactat ttgcaatacg
      901 ctggacttga taagaatatg aaaattaaac tatttcaaac aattttggaa atggtggcaa
      961 ggaaaaaaat aacattatca agcgatagcg aatttacaga aggaatatta caaagtgatg
     1021 aagcagaaat gacgacgaat gtaggattta taatcgaagg attaagttat cataatgact
     1081 aaatctttag cattaaaaaa gcagtgtatt tattaaatac actgctttta tttccgcata
     1141 gttaatataa aataatgtga tattatatca tgtgaatata gattaaattg atatttaaat
     1201 cccttatagt taatctaaaa aataccatta tatcatttct ctataaatta aattgacatt
     1261 taaatccctt gtagttaata taaaaattct tattacaata ttatttctaa ataaattaaa
     1321 aaatatttta aatccctcgt agttaatctt aaaagcgata ctatatacat taataataat
     1381 actcttctac ttaattttca actatatttt gtaattcttg tttacaactt tcaatgcctt
     1441 ctcgtaattc ttctaaaaaa actgatgtgc tatcgtctat atttctttca gcaatttctt
     1501 caaaattttc tttattgaat tttttataac tatcccaatt caaactttcg catttatttt
     1561 cgcaccaatt ttcaaattct tcgtaatcat ttacgtagta aatttctcca aacatatcgt
     1621 ctaagttatt tcctgtttgt cttgatgtga aaatattaat ttctttatca tcatctaaaa
     1681 gtttagcata agcctggatt gctatcgctt caacttttcc ttgtatatcg atataaattt
     1741 ttatatcatt agtctctttg attaaacaac tttctttaaa agcttttata gcttcttcct
     1801 ctattttatc tatattcata tctataacct ttaaaaattt tttagcttct tttttatcca
     1861 ttttatccat tttaatttcc tccatttttt agttattttt tatatataac agttctttcg
     1921 ctcttttcaa tttctgtaag atactctaaa aattctttaa tttcttgctt gtttatgcct
     1981 ataaattcgt gtctaatttc acatttttca atacgtgtag aatatttctc ttctaattta
     2041 taaaatttag gtcttacatt ggctataagg tcactttcta catttttgct acacaagcta
     2101 tttacatata ttaaaatgtt ttctatattt tctatgtcta ctttgtcgcc ttttgaataa
     2161 taaaaattaa atctcaatct tattcctatt ttactgttaa tttcaccatg accccacgtt
     2221 tcaatgttta aactttttcc aactgtttct ttaacgcttc caatgtgacc gttcgcacaa
     2281 tctttaagac ttatatcaaa tatatcattg ttgattttat taatctcttt ttctatcatt
     2341 ttaacattct ctttattaac ttttaaatct aatattgtac taaaatctat attcatgttt
     2401 taaacctcca attatttttt attttaatta tagcattcaa tggtgaacta tatttgtatc
     2461 aagttgaaac ttttaacact ctacgccatc tctgaatact tggtatgcaa tttctatttt
     2521 tctttcatca ctttctattt ttctatagtt ttcaatctgc ttctttttaa tgtctgcaaa
     2581 tccatttcta taaaattgtg catttttttg tattaatgtt tctattatgt attttttagc
     2641 tttctctata tattctgtgc tagtagcttg ttttactgcg tcgtcaaata tttcaactat
     2701 ttcaagtaca ttttctttta tttcattaga ccaattatca ttaaaattta tttctttagc
     2761 tattttctta gcttcttcat agcttatact ataatcttta acttttttaa gtctataaga
     2821 tgcttgtgtc tccccttgta aaaaactcca atttctgttc tcttttgcaa attgagaatc
     2881 ttttaatatc tgatttatat gaaatgcttt ttgatttaaa gaattatact ttaaaacatt
     2941 tctaaaatta tctataaaga acttagcatt ctctatattg cttattgctt ctcttattct
     3001 ttcaaatttt cttttacatc tttctgtcat ttcttctata ctcatgtctt taattttgta
     3061 gtcttcattt tttattcttt ctattttact tttttctagt tcgttagtta aatttaaaat
     3121 gtctgttctt atatcattag cccaaataat ttgtttttct gaccctttta attctttcaa
     3181 ttttatatcc ccctttttat ttaagaatga taagcaaaga ctaaattgta ctttataatc
     3241 tacattacta tattttcttt ttatttctct tgccatttta tgcgcttctt taaataaaat
     3301 tttcattctt tgcttacccc cttgttttat ttgttaatta tattataatc tatatgaata
     3361 tctaagtcaa cactttttca aagttttttc tttgatttcc aaaaatataa ctttgattag
     3421 cgtagattat tcttttactt ttaatttttt tatgttatta tataaataag agaggtgcga
     3481 aaaaatgaca tggaagaatg aaattaaaag tattcttgta aaagaaaata tcagcatgaa
     3541 tgagttaaat aatttaatga atgaacataa taataagaat aatacagttg aaaatttaag
     3601 acaaaaaata aataatgaga ctatgaagta tagtgaaatc ttgactattg ctaatttgat
     3661 aggatatgaa gttgtttgga aaaagaaaga aaagtagaca taaaaaaaga aggtaacaac
     3721 taactagttg ctaccttcta atctatctat caataaaatc taatactttg tgaagtgtat
     3781 caaatctatc attacctttt atcatagtat aattttcttt agtcatagaa cttatctttt
     3841 cacatgctcc accaccaaca acataaagat tttgtgtctg gccaggtaca taatctttta
     3901 tatcacatat cagtattttc ccatcattat agccccagcc aactacagtt gcaggtattt
     3961 tgtcaacttc tccatcataa acgattgtat gtttgtacat gatttttccc tcaccattct
     4021 ctttgttatt tatattttta tttaatatac cctctgctat aagttttgca actgtatttt
     4081 tatttttaat ataataatct gtatctgctt tactatctac gaagcacacc tcaatcaata
     4141 tcgctggagc ttttgtatgc ttaagccagt aaagacctct tacatctgat tttgcacctc
     4201 tattttcgaa tactgttgct aatttatcat taactctttc ggcatatacc ttaccattgt
     4261 tagttttgta tattgtctct gtacccatag gatttagagt tgttttattt gcgttgaaat
     4321 ggatttgtac tgctaagtct acattttgcc tatttgcaat tttacattgt tctgctaagt
     4381 agttattaga tttatctact tttccagtat acacaatagc tccaccttgt ttcaaccatt
     4441 taacaattaa atcagttaaa attctatttt cttttccttc gtctatatag ccagttgctc
     4501 ctgttccttt tccacttaaa gtgtgtcctg gtactattgc tattttcatt atttatcacc
     4561 atccttcaac tgtttgtaaa cttgatttgc ccctattgca actccccaac ataaaattcc
     4621 ttgtaaaatt gatgaaggat taaatcctaa catccatatt gaaaatccaa ttcctatcac
     4681 aagcaatatg attggaatgt atttattatc taactgtttg tatttcttaa atccaaatcc
     4741 taatacatta agagcaacta ctaataaaag cagttgctct ggtataaaac ttattaaatt
     4801 atccatatct taacctccta attaattaaa atattccttt ctgtatggca aatataaaga
     4861 accctactaa agttgtaatt ataactccta caagccactt gagtactcct gtcagatttt
     4921 ttatatcact acataggttt tgtatttgta tagcaaactt tgcttgctca atctcgattc
     4981 tatcaatttg tttgccgtgt tcttttactc ttgtttcaag tgtacttatt ttttctttca
     5041 caagttcttc attcatgaaa acctcctatt gctttgtatt aaaaaaagaa cattacctat
     5101 tttgtaagtt ctgctccttc tactacctca ctatgttcta taatgtagtt ttcaactgcc
     5161 atcctgtact ctgtgttagt aacatcatca agttcaaata ctctattttt tagaggattt
     5221 aatcccttat ttaatattct ctctgctaat attcttacta caacattatt tatattcatt
     5281 ataaaattcc tcctactttc tcattttcat ttaataaaat ttgattttct aactcttgta
     5341 ttctcttttc ttcatctgaa ataaatgttg gtatttcctc taaaattggt tcttttgttt
     5401 ctatatttat acctataatt ctatttcttg tatagtctat acttccatac ggaatatcaa
     5461 caaaatgtaa ttccgttatt tcatcatgtt ctaatatatc ccctgttgct tctccagttt
     5521 ggagtaatat tttcccggtt tggtcacata taattctatt tcctctttcc atttaaatta
     5581 ccacctttca tattattcat aagcatacca tgtaaaactt tctccgactt tacaacggta
     5641 tactacgcta ctactatcag tgtattcatc tcgataagta tataaagaaa attctttgct
     5701 agtaatagtt tttacaaaca taaaagcaca aaaacgatat tctccactac tcttaggaac
     5761 acgaccaaca gaagcaagtt gatttaaatt attaatagca taaaaattaa cagtataccc
     5821 atttccataa aaacaaagtt tttcaacaat gacaagacta gggatgaaat ttaaattaat
     5881 aggaacagta agactcttag cataattttc agcacttgaa taccttgaat aaaaattttc
     5941 ataatcactt tgagtaaaag tgtaagtacc cttagcccat cttttacgtt ggcttaactg
     6001 attatttaaa ttagtaatct gattttgaag ttgttcagca gtagcatctg aactatcaaa
     6061 acctgttttt attttctctg ataattcaac taatgtatta tttaaatttg cttctatatt
     6121 ttttaatgct aaagtgttta taatacttgt ttttccagtt ttaaatcctg cattaacttc
     6181 aattagttta gaagatatgt cttgcagatt cacatcttcg ggcaatggca ttatattctt
     6241 acttatactt aacacttttt ctgctgtagc attattactg tctgtaacaa ctatcttaag
     6301 tgtgtgtagt gcattatctt ctagtgtata gttaattgtt ttctctgttg ttaaatctgt
     6361 tgttatagtt tcttttaaca catcatctat aaaatattct atttttgtaa gca
//
LOCUS       DAYAKB010000137         6092 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.138, whole genome shotgun sequence.
ACCESSION   DAYAKB010000137 DAYAKB010000000
VERSION     DAYAKB010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6092
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.138"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            124..570
                     /locus_tag="ACGI3L_003583"
     CDS             124..570
                     /locus_tag="ACGI3L_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199262.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEELDLHEDAKKDNIYKEDEYKKYEEE"
     gene            855..1559
                     /locus_tag="ACGI3L_003584"
     CDS             855..1559
                     /locus_tag="ACGI3L_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199263.1"
                     /translation="MLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSGKEMISSN
                     EYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGGDDYITKP
                     FRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFLTSVEYKL
                     LLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCEPIYIETV
                     RGIGYKWIGSENSVSI"
     gene            1537..2790
                     /locus_tag="ACGI3L_003585"
     CDS             1537..2790
                     /locus_tag="ACGI3L_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9199264.1"
                     /translation="MKIVFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMV
                     VRNNQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPI
                     ISKLVLETIKINIILVCIIFILIFVLIVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKN
                     KNQEGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLND
                     LLYNDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHR
                     AMLSMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITY
                     KENPLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNG
                     DIYVNSEKGKGTEFHIIFHKMYDSD"
     gene            2870..3547
                     /locus_tag="ACGI3L_003586"
     CDS             2870..3547
                     /locus_tag="ACGI3L_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199265.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQVSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            3548..>6092
                     /locus_tag="ACGI3L_003587"
     CDS             3548..>6092
                     /locus_tag="ACGI3L_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199266.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVKNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIVCTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNI"
BASE COUNT         2566 a          554 c         1024 g         1948 t
ORIGIN      
        1 aacaaacaca aaatataagt ttatattttg taaaaattgt aatttaaaaa ataacataat
       61 ttttattaaa ataatacaga tactatttat agatagaaat aaaaattaga aaggagaaaa
      121 aatatgttaa catatttaat gaaaagacaa atgcataaaa aagatgatgg aatgagtaaa
      181 ccaatgatga ttacaggagc tgtaattaca ggtgtaggag catatgctgt atataaaatg
      241 gtaaaaagcc ataaatctaa ttctcaaatg gtcaatacaa attattatgg aaatagcgat
      301 tatgatgatt ataaatatga cgaatttgat tatgactgtg attgtagaga cacaaaacaa
      361 gattatgaat atgaagaatt aaaaaaaaaa gtaaaagaat ttaattcaag aagaataaat
      421 tgtgaaaatt gtccacatgt ttctcaagaa gaaatgatgc aatatgtaaa tagtgttaaa
      481 gatgtaaagg aagagcttga tttacatgaa gatgctaaaa aagataatat ttacaaagaa
      541 gatgaataca aaaaatatga agaagaataa gtaatatttt gtataactga acaaatagta
      601 atgtcaaatt atttaatatc tagttttaat atgtaagttg taacttaact tgaaagaatc
      661 agtatcattc tttagatagt taagtaacaa cttacatttt atttttataa attttaatag
      721 ttctttgtga ctattttgta attttagaaa tattttagta tccagggtaa ttgtgtataa
      781 taaaacttgt atagatagat agtatgaaat taagcagata gtttaaaatt aaaatgaaaa
      841 gaaaggaaat agttatgtta aagttgttga tagttgaaga tgatagtact atatcttttg
      901 gaataaagta tgctttagaa caagaaggat ttagtataga tatatcaaag gatttatcta
      961 gtggaaaaga aatgatttct tctaatgaat atagcatgat actgttggat gttacattgc
     1021 cagatggaac tggttatgag ctttgtcaat atataagagg attctctcag gttcctataa
     1081 tattcttgac tgcttgtgat gaagaagtaa atattgtaat gggtctcgat ataggtggag
     1141 atgattatat aacaaaacct tttagaatta gagaattaat atccagaata aaagctgttt
     1201 taagaagaaa aggtaatact tcagaagaaa ataagaaaat acttaaattt ggagatttaa
     1261 gtatatatac attagaagct agagtatata aaaatgataa agaaatattt ctgacatcag
     1321 ttgaatataa acttctttta attcttatac agaataaaaa tactgtttta agtagaactc
     1381 aaatattgga aaaactttgg gatgtaactt atgattttgt aaacgacaat actctaactg
     1441 tttatataaa aaggcttaga gaaaaaatag gtgatgattt atgtgaacca atctacatag
     1501 aaactgtaag ggggattggt tataaatgga taggaagtga aaatagtgtt tctatataat
     1561 ccagaagtga agaagttttt aagtaagtat gttactttga tgtttattgt tatcataata
     1621 tctattggat ttagcataat caacgtgtcc ttaactaaag agatggttgt aagaaataat
     1681 caggctataa taggaacttt atcaagcaag tatccaaact tagaaagtca gatagtagac
     1741 ataataactc aagggaagtc tatggagaac atagattatg gtcagaaaat attaattaag
     1801 tataattatg ataaatctat taggataaac tctgagccta ttatttctaa attagtttta
     1861 gagactatca aaataaatat aatattagta tgtataatat ttattttgat atttgtgttg
     1921 attgttagat attttacgtc aatttacaat gatttatcag atatgactaa gtatgtttac
     1981 tatagttcag agggtaagcc atttgatatg aaaaacaaga atcaagaagg gcagataggt
     2041 cttctaaaaa ctgaactctt aaaaatgacg acaattctta atgaaaaggt tgaactttta
     2101 aaaagagaaa agatattttt aaacaataca atttccgata tatcacatca attaaaaact
     2161 cctatgactt ctttaataat gttgaatgat ttattatata atgatgtacc atacgaagta
     2221 aaaatcgatt ttttaaataa gataaaaaat caattaaata gaatggattg gttgattaaa
     2281 agcatgctta aattatcaaa ggtagaagca aaagtgataa attttaaaaa agataaggta
     2341 aaatttagtg aactcataca tagagcaatg ctatctatga aaatacctat ggagattaaa
     2401 aatcaaaaac tgactataga gggaaatgat aatgtatctt atattggtga tattgattgg
     2461 tccgtggaag cattagtgaa tataatcaaa aattgtgtag aacatactcc tgaatttgga
     2521 aatataatta taacctataa agaaaatcca ttattttctg aactaataat aaaagatgag
     2581 ggtgaaggta tagataaaaa agatatacca catgtattta aacgattcta tagaggaaga
     2641 agtagttcaa aagaagatag tgtaggaata ggtcttgcaa tgtcaaaatc tataatagaa
     2701 agccaaaatg gcgatatata tgtaaacagc gaaaaaggta agggtacaga atttcatata
     2761 atatttcata aaatgtatga tagtgactaa tctgtaatat ttaattcact ttatagtaat
     2821 agccaaaacc taatatatga agtatagaat ataaatattg gaggtagtta tggaaatttt
     2881 aagagtagaa aatctaacta aaagttatgg taaaaatgaa acaaaagttg atgctataaa
     2941 aaatgtaagt ttatcagttg aaaaaggaac gtttatagca ataacaggtc caagtggaag
     3001 tggtaaaagt accttattac atttattagg aggagttgac agaccaacta gtggtaaggt
     3061 ttatataaat gatgttgata tatataattt aaaaactaag gatttggcga tatttagaag
     3121 aagaaatata ggtcttatat atcaatttta caacttaatt ccagtcttaa atgtgaagga
     3181 aaacatattg cttccagcag agcttgacaa tagagatatt gatagagaat attttgatga
     3241 tttaatgaaa acattaggtc taattgatag agaaaagcac cttccaaacc aagtatcagg
     3301 aggtcaacaa cagagaacct ctataggacg tgcattaatt aatagacctt ctataatatt
     3361 agcagatgag ccaacaggta atttagatag taaaaattca aaggaaatat tagaattgtt
     3421 aaaattgtca gtaaaaaaat acaaccagac actaataatg ataactcatg acaaaaatat
     3481 ggcacttcaa gctgatagaa ttataagcat agaagatgga atcataaaaa gtgatgaggt
     3541 gatgtagatg aatttatata catcactaac tattagatac ttaaaacaaa ataaaagaag
     3601 aaccattgta accataatcg gtataatact ttcaacagct ttaatttgtg gtataggaaa
     3661 tatatttgaa agttttatgg attatcaaat gagagaaact ataaagaatg atggaagttt
     3721 ccatgttaca ttttatgatg taaatagaaa aaatgtggaa tatgtaacga aatcagctga
     3781 aatagaaaaa catgcattta ccaaacaact tggatattct aaattagaaa atagtgaaaa
     3841 tgctatatta agtataaagc aatatgataa aaatgcaata aatggatata aagtttctat
     3901 aaaagaaggt agatttccag ctaaggaagg agaaattgtt ttaagtgaaa gtattattaa
     3961 tcttatagat gataagttaa aaataggaga taagataact ttaaaagtag gggatatgtt
     4021 tgactcaagc aagaaaaaga ttgatagtat gacatttcat gaaggtgatt atatagcaaa
     4081 tgaaaaagat agaactttta aagttgttgg tataattgaa aaacctgggt ttgaacgtta
     4141 taatggaatt gcaacagcta tagcctactt taatcctatg aataattaca atgatacaat
     4201 taatgtatca gtagcagtaa aaaatcctaa agatgtgtat aagataagta ataaaataag
     4261 taaaaatata tattcaaata aagataaaga agcagtttct gatatgataa aatacaatga
     4321 acatttattg aggttacaag gtgctagtaa gtattcaaat ataaatagct ctataaagtc
     4381 tataattata gcagtaacta ttttagtaat cgtatgtaca attgctacag tgtacaattc
     4441 ctttagtatt tctataaatg aacgaaaaaa acagtttggg atattaaatt ctataggtgc
     4501 tacatctagt caaattaaaa gattagtttt tatagaaggt attataatta gtttaattgg
     4561 tataccaata ggactaatat ctggaacagt agctatagac ttattgttta aaattataaa
     4621 taagtatttt actgaatcgg ttgttactaa gatgagtttg cagatagtgt ataatccaat
     4681 aataattatt gttagtataa taatagtttt gcttacaatc tttatatcaa ttctactacc
     4741 tgcaatatcg gcttctaata tttctcccct taatgtgatt aaaaatactg gagagtataa
     4801 agtgggcaaa atcaaaagct caagacttat taaaatgatt tttaaaactg aaggagtact
     4861 tgcatataaa aatattagga gaaatagaaa aaaatttata ataactcttt tttctttaat
     4921 ggtaagtata ataatattta tatcttttag tggctttaca ttacttttac taagaggtga
     4981 agaaattaga aattctcaaa gaaaatatga tttgtattta actgcaaaga acacagctag
     5041 gtctgtagag gatactataa gtgaactaga agatattgat gggataaaaa actttgaatt
     5101 ggcaacagga caatatgtgt ctataagagt aagtgaaaat aaaataaata aatccaagga
     5161 agatttaatc aggaaatatt atcaaaaata taagattgga gatagttatg aatatgattt
     5221 cagtaataat gaattaattt ttccaggaga ttttgcagta aaaaacaaaa taaataactt
     5281 agtacagggc tcttttaata aagagagagc aattgaagaa aatggtgtta tattagttag
     5341 aaaaagtgca attgaagaaa atgggaagaa aggtgtagta gaacttacca actataaagt
     5401 aggagataca gtaaattgtg aatatcttga tgaaaatgcc ttaagtaaaa aagtaaaggt
     5461 caagattctt gctataactg acgaagaacg tctaggtctt ggttatcaaa atatggggtt
     5521 acaatttata acttatgatg aagttgctaa aaatttaaat ttaaaattaa gtaaaagcct
     5581 tatatttatt gattcaggag gaagcattaa gactaagaag gaaatagaag ctttggcaaa
     5641 taaaaataat tttaactttt atgatgaaag tgcaagcaat gaaagtgaaa aacaagattt
     5701 aaaggttatt aaaatatttg tatatggttt tatagtagtg atatctttag tgagtgttac
     5761 aaatattcta aatacagtaa gtacaagtat aaatctaaga aaaagagaac ttgcagtaat
     5821 acaatctata ggggttactc ctaaaggatt taggaaaatg atatatttag aaagttttat
     5881 atatggtata ctgtcattgt tgtttggaat accaattagt attggtataa ttctaattat
     5941 gaataaactt atttcaggtg taattgaatt ttctccgatt ataccgtgga cagccatagt
     6001 tatctgtata gtaagtgttt ttataataac ttttatagca gggtatatac caatgagtaa
     6061 attaaataaa gaaaatataa tagataatat aa
//
LOCUS       DAYAKB010000138         5918 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.140, whole genome shotgun sequence.
ACCESSION   DAYAKB010000138 DAYAKB010000000
VERSION     DAYAKB010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5918
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.140"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(80..226)
                     /locus_tag="ACGI3L_003588"
     CDS             complement(80..226)
                     /locus_tag="ACGI3L_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199267.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            322..645
                     /locus_tag="ACGI3L_003589"
     CDS             322..645
                     /locus_tag="ACGI3L_003589"
                     /inference="COORDINATES: protein motif:HMM:NF024502.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFG9199268.1"
                     /translation="MKDRECSFSPNTIRNRKNMIKNQIEVFFKDMKLIDITPSILQSY
                     INNIYNEHMLNSIKNQVDFIKSVLKESYRLKEISENICDFVTTPIKKVVQLLSFIQNK
                     KLNYY"
     gene            1512..2867
                     /locus_tag="ACGI3L_003590"
     CDS             1512..2867
                     /locus_tag="ACGI3L_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9199269.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(2985..3644)
                     /locus_tag="ACGI3L_003591"
     CDS             complement(2985..3644)
                     /locus_tag="ACGI3L_003591"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HFG9199270.1"
                     /translation="MLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTISEEH
                     GKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAYGDI
                     DIESHRKWDTDRCEAVGMKVDLPLWQESREELVYEFIDSGFCSVVTKVNLKHLGEEFL
                     GKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGYLEI
                     K"
     gene            complement(3720..4148)
                     /locus_tag="ACGI3L_003592"
     CDS             complement(3720..4148)
                     /locus_tag="ACGI3L_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9199271.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            4300..4848
                     /locus_tag="ACGI3L_003593"
     CDS             4300..4848
                     /locus_tag="ACGI3L_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HFG9199272.1"
                     /translation="MYTNFNIDFNNFNKKENAIKFMLMGVLLIILGLLCLTFKTLGIK
                     LISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVLIIACILLFVFPQKIQ
                     SIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSI
                     MSFFIILFGLVLFFSGNTARKY"
     gene            4967..5902
                     /locus_tag="ACGI3L_003594"
     CDS             4967..5902
                     /locus_tag="ACGI3L_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFG9199273.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNKIDDTLKARNSYQGCKFV"
BASE COUNT         2115 a          819 c          759 g         2225 t
ORIGIN      
        1 ttctattgag atatttaaac atatatttac tgcttcataa aaatcaaatt cattaaaaaa
       61 tccattttta tttacaatct tatatccctt tgcatctctt tctaaatact cttcctaaat
      121 actcttcaaa actttcatca tctaatctaa atcctatatc actatgaaaa ataggttttg
      181 catttggata tagttctatt gttttatcaa aagtttcgaa taccaagtta ttattattcg
      241 attttccaat agtccactat aaacaataat aagtttgttg ctccaaataa tgtaacactt
      301 gtagaaagat gttacagata tataaaagat agagaatgta gtttttctcc taatactatt
      361 agaaatagaa aaaatatgat taaaaatcaa attgaagttt tctttaaaga tatgaaatta
      421 atagatataa caccttctat tttacagtct tatataaata acatatacaa tgagcacatg
      481 ttaaattcaa taaaaaacca agtcgatttt ataaaatcag tattgaaaga atcttataga
      541 ttaaaagaaa tatcagaaaa tatttgtgat tttgttacaa ccccaatcaa aaaagtagtt
      601 caacttctaa gctttataca aaacaaaaag ctcaattatt attagaaaaa tcaaaaaata
      661 ttcctatagg tataccaatt tttttgatgc taactcttgg attacgtttt ggtgaagctg
      721 tatcacttat atggtcagat gtagaccttg ataaaaaatc tcacatgtaa atcaaacatt
      781 agtttatgta tacaataaaa taatcttcaa agaccctaaa acccctatat caaaaagaaa
      841 attatttgct cctgatgaac ttataagttt gcttaaaggg gaaaaattaa aacaaaataa
      901 gttaaaatta cagggtatat tgaaaaatga atttgatttg atatgcttaa ataaaagatt
      961 caacccgtga gttcaaccaa cttttgttgt tcattttaaa aaactattaa gagataataa
     1021 tcctagagat ataaaagtac atgaattaat acatgcaaat gcaactttga tattactttc
     1081 aggtactaac ataaaagcta tttataaaat attagtacat gcagatataa aaatagctat
     1141 gaatatatat tccatattct cacttattag atgaaatgaa taaagaaaca tctgaaaata
     1201 taagcaaaat actattcaaa taatgttcag ttttatgtca attaaatgtc actcaaagtg
     1261 cttttttttc atttgtcagt taaatgtcac ttaaagtacc tttttcctat ttgtcagtta
     1321 aatgtcagta atatataaat aagatatatt tataagaccc ttaaaatcac tattatttaa
     1381 taaaatttat aattatatac tatttgctgt tgacattggt attataccat agtttatcat
     1441 ttatattaga aataaaatta ttaattaata gtttcgtaat tttataatag atttacaggg
     1501 agtgatagta aatggataca aaaatatcta taaacgaaaa catgagtcta ggtaaaagat
     1561 tttttaaata cctagcacca tctgtagttg caatgtgggt tttctcacta tatacaatgg
     1621 ttgatggaat atttgtaagt aaaggagttg gagaattagc tttagctgct gtcaatatat
     1681 caatgccttt tattaatttt atatttgcag tttctctatt attttcaact ggtgcatcta
     1741 ccataattgc aatctatctg gggaaaaaag atattaaatc tgctaacgaa gtcttttcat
     1801 ttaacttagt atcaataatt atattatcaa taattatatt agctataact ttttttaatt
     1861 tagatagatt agcactattt ttaggagcta cagaatctac aattggtatg gttaaagatt
     1921 atttaggaat aataatattt tttaacggat tctttatagt gtcttattct ttagaagtta
     1981 taataaaaac tgatggcttt ccaatattag ctactgttgg tgtaataata tctgctctta
     2041 caaacatcat acttgattac ttgtttgtaa ttgaatttgg atggggtgta aaaggtgctg
     2101 gtattgcaac tggtttgtct caagtctttt ctactatttt cttcttaata cattttttaa
     2161 gaaaaaactc tactttgaat ttttcaaaat ttagaattga ttttaagaca cttagaaaaa
     2221 ttgtatttat aggttttcct gattcaacta ctgaattaag ttgtggtata gttgttttac
     2281 tttttaactt aagtcttact aaatatattg gagaaaatgc tcttatttat tatagtgtca
     2341 taaattatat aaatacatta gtacttatga ctatgatggg tataactcaa ggtatgcaac
     2401 cacttactag cttttattat ggtgcaggaa atatagataa tgtaaaaaaa ttattaaaaa
     2461 tggggataaa agccacaata atagcatcag ttgctgtatt tgcaatttgt atggcttttt
     2521 caggaccaat agtctcttta tttatacatc cagaagaaac aatgctattc aatgaaggag
     2581 ttcgtgtatt taaaatattc tctatatctt tcttattggt aggaattaat gtaataattt
     2641 ctggattctt tgtatcagta gaaaaaccat caatttctac tgttatatct cttggtagag
     2701 ggcttgtaat agttgtttta agtctaattt caatgatact aatatttggt ggacaaggaa
     2761 tatggatgac tactattgtt tctgagttta tatgtcttat tttatcatta gtttttctaa
     2821 aaaagaattt ttctacatta gactctaatc taaataaggt tgcttagatg ataagagtga
     2881 caatatatga aaatatctaa ataaaaaata cctattatac aatcttgcaa atattaaacc
     2941 tttgcaaaaa ttaggattat ataataggta ttttatttat gtaattattt tatttctaaa
     3001 tatccatagc catcttttat taaagttcct tttacttcat attctacagg ttttttaaat
     3061 attggaccat ctacgacaaa tgtatgatac tctccatgtt ctccacatgg gtctgcacca
     3121 gcatttttta tcttctccac aagttctcta gttaattttt ttcctaaaaa ttcctctcct
     3181 aagtgcttta agtttacttt tgttacaaca ctacaaaatc cactgtctat aaattcatat
     3241 actaactcct ctctactctc ttgccataat ggtaaatcta ctttcatacc aactgcttca
     3301 catctatcag tatcccattt tctatgactt tctatatcta tatctccata tgcacatata
     3361 gttgctccca tgtttttagc ttttattaaa gccctctcaa agctctcttc atatccttct
     3421 acaccacact cagcaactaa taaaggtaat cctatattgc tacttacttg cttaagcata
     3481 ttatattcta aattatgtgt ccatgacttt ccatgttctt cacttatagt tgtcaagagt
     3541 gccacaggct tatatccttt tttcaacatt cgatttaatg ctaatatact atccttacca
     3601 ccactaaatg acattacaaa tttttcatca gccaatttta acacctcttt catctaactt
     3661 tgttttatta acataattat accaaatttt tgagttgcat agcaaattat attaaattgt
     3721 taattcacta taaagaatgt ccctaatatt aaaagtataa cccctatgta tttgtataaa
     3781 tgcattgttt cttgtcccaa aattacgcta tcaataaaaa atccaactaa aacttgggat
     3841 acaagagtta atataagtgt atttgatact cctaaatttg gaattgcctt tactgtaaaa
     3901 tatattatta gacctccaaa tactcctcct aataacaact tataattaaa accatttata
     3961 gatactagac actttaagtc acctgtaact attatacttg ccaaaaaaaa tattgctcct
     4021 acagttaagc ttataaaggt ggccactaat gctgttgtac tttttcctag ctctccattt
     4081 ataaaagctt caagagctgt agaaccacct gctaataatg caaatattat tgcccataat
     4141 tttgtcatgg acaaacctcc ttctatataa ttctattaat agaagtttat gatacaacct
     4201 attaattaat tactaagtat agtttaattt ttatacacta ggctttattt ggatatgaat
     4261 ttctgttata attgttctat cgattttgga ggtgatttta tgtacacaaa ttttaatatc
     4321 gattttaata actttaataa aaaagaaaat gccattaaat ttatgttaat gggagtatta
     4381 ctcattatat taggattatt atgccttaca tttaagacat taggtataaa attaatttct
     4441 tggacttttg gtattgcact tttattcttt gcatatttaa atttaaaaaa tattaatgaa
     4501 ctaaaaagat atgctactaa agaagaaatt aaaccctcta ttaatatcca atgggttcta
     4561 ataattgcat gtatattact ttttgtattt cctcaaaaaa tacaaagcat attttcatta
     4621 tttttaggat tttatttaat ctttaatcaa ctagtagcac ttgtaaatag taagaataat
     4681 ccttattcta aatttacaac ttggaatata gttaagattc tatttggtat atgccttata
     4741 ttatctccac tttttttatc tagatttata gtatcgataa tgtctttttt cataatatta
     4801 tttggactag ttctattttt ctctggaaat acagcgagaa aatattaatt attttctcgc
     4861 tgtattttta tattacttaa aatagaattt gtttaagtta tctatttgtg gtaatatgtt
     4921 ttttgtacaa gctcagcgta caattttatt agaaataggt gattttttgg ataaatttaa
     4981 atatgctttt gataataaaa gatatcatac ttggaattac tatcttagaa atacttttgg
     5041 agaaaaagtt tttaaggtat ctataaatgc aggatttact tgcccaaaca ttgatggaag
     5101 tcttggttat ggcggatgta cctattgtag caaagaaggc tcaggtgatt ttgctggaaa
     5161 ccctaaagat aatcttatca gtcaatttta taatataaaa gaaatgatgt taaaaaaatg
     5221 gcctcatgca aagtatattg gctactttca agcctataca aatacgtatg ctcctcttga
     5281 agttttaaaa gaaaaatatg agactatatt agaacttgaa gatgtcatag gtctttcaat
     5341 atccacaaga cctgactgtt tgccagatga tgttgtagaa tacttgtctg aactaaataa
     5401 aagaaccaat ttatgggttg aacttggact tcaaacaatt catgattcta catctaaaat
     5461 tataaataga ggtcatgatt ataaaacatt tgttgaaggt gttgaaaaat taaagtctaa
     5521 aaatataaag gttgtcgtac acattataaa tggtcttcct ggtgaagatt ataatatgat
     5581 gatggaaaca gcaaaggcag ttggtaaaat gggtgtagac ggtataaaaa tccatctatt
     5641 gcatgttata aaagatactc ctatggaaaa gatgttacaa aatggtatgt taactcttat
     5701 ggaacaagat gaatatatca atcttgtctg tgaccaatta gaaatacttc ctgaaactat
     5761 gataatccat agactcactg gtgatggtaa gagggatgaa ctagtaggtc ctatatggag
     5821 cctaaaaaaa tgggaaattt taaataaaat tgatgatact ttaaaggcta gaaattctta
     5881 tcagggctgt aagtttgttt aatacaaaat aataacta
//
LOCUS       DAYAKB010000139         5900 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.141, whole genome shotgun sequence.
ACCESSION   DAYAKB010000139 DAYAKB010000000
VERSION     DAYAKB010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.141"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(460..2193)
                     /locus_tag="ACGI3L_003595"
     CDS             complement(460..2193)
                     /locus_tag="ACGI3L_003595"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9199274.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(2433..3278)
                     /gene="dccA"
                     /locus_tag="ACGI3L_003596"
     CDS             complement(2433..3278)
                     /gene="dccA"
                     /locus_tag="ACGI3L_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP diguanylate cyclase DccA"
                     /protein_id="HFG9199275.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            complement(3309..5543)
                     /locus_tag="ACGI3L_003597"
     CDS             complement(3309..5543)
                     /locus_tag="ACGI3L_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9199276.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
BASE COUNT         2005 a          826 c          677 g         2392 t
ORIGIN      
        1 attaacttta taaaacccag taattgcaac acttttatag ttttatatta actaagtggt
       61 atataaatag tataatgttg aaaagttaga gagtacaatc aagaaatttt acattaacta
      121 aaatgtatag aataaaacat gtatttatac ttaaattctg tacctatata aaaaagtgaa
      181 ctctgtcaac aaagcacttt tttatataga taaattatca ttttgtttta agatagaaga
      241 tactaatgat aactgtttat cattagtatc tgtatgtata taaaagttta attttttata
      301 taaatttgct ctttagaaaa atgagcagta tcaataaata tattgtttaa attttttcta
      361 ggaactagtt gactagctat aagattagct tcaactcttt gattgttaga ctatgaaatt
      421 aaatttaaag gttcattctt ggtcgtataa atagctttat tattcgtatg tactataaca
      481 atttttgcca tctgcttttg atagataaag agctttatca gctttagaaa ataaatcttt
      541 atataattta gttgaatcat cagtgaaggc aataccaata cttaatgtta ttttatgatt
      601 gtcctttact tttattttac tcgcatcatt taaaatatca ttagtaattt ttattattaa
      661 atcctttgtt aatgatttta taaatattgt aaattcatct ccaccaattc gagcaactat
      721 gtctttatca tgtgtgttat gtaatagtat ttttgataca gcaactaaaa cttcatttcc
      781 ctctagatgc ccaaaagtat catttacagt tttaaaatca tcaatatcaa taactaatag
      841 agcatcatta tttttggaat cagaactaca tagatactct tcaataagat tttgtgatac
      901 tctttgatta tataattgtg ttagtgggtc acgttgagcc tgattaatta aactttctaa
      961 tttagattta tcttcagtta tgtcttttaa aacgcctatt gttttgatag ggttatggtc
     1021 actatcatat ataactgaac attgaacacg aatccatctc cattcatttt tagttaatga
     1081 atttacttgt cttatctcaa ttgtttcacg aagatttcca tgaagtactt ctagtagttt
     1141 tccaatatca tcaaggtgaa taattttacc agattctaat agtttggagt aattttttgt
     1201 ttcaaaattt tctaattcaa tttttttgtc aatttctaca cgttgatatt ttataagggt
     1261 atcgttttca atatcatact caaacatgat atctgtaata ttttgcaaag caatacgata
     1321 tcgctctctt tctaatttta gttcagattc tatgtttttt agttgggtta tgtcagtaat
     1381 aatactatta atttttacta tgccatcact atttaacgat ttcattccag aatctaatac
     1441 ccacattaat gttccatctt tttttcggat tctatattca gatgaatatg taggtccttt
     1501 tgcaaaacat cgttcacaat cttctagtgc tttaggtaag tctggtggat atacagcacc
     1561 cactgctgaa ccaccactca tttccatgaa ctcatcatat gtgtatccta atattttggg
     1621 caatccctca ttgacataga aaaatgagta tgtactatca tcattgctac cttttaagcc
     1681 accattgata ttatttgtaa tcatttcaat aacttctgtt ttttctttta gtaatctttg
     1741 caaataatca taactttgag ttccaatttt agtgggaaag tattcatcaa gttgcatttc
     1801 accataaggg tttgatatgt gcatgtgctt tattaataat tttcctctat cctcaattat
     1861 ctcaaatgta caacgttgat ttacctctaa aatcatttga gcattttctt tagttcgaac
     1921 agtatatctt cctaatacca tacatctatt ctcatcttca cttacagttt caaatatatc
     1981 attatttata tcacaagaag gaatttcatc ttgacctgca taaaaataat tttttatttc
     2041 attaaaagaa gtgagaaatt cctgttctcc tggtccaatc catgtaacat tttcacaaag
     2101 gtattttaat acttcattga tatctcgatt tatataaaaa cttgttataa tatgttttgc
     2161 taatttgggt gcttttttta ggagtatgct catgatattc ctcctttctt tttgctatta
     2221 tattttaatt atattataca tcaatatatt taaattaaaa gctttgttaa actatgatat
     2281 ctttgttaaa taagttaatt ttaacaaaaa agaactgaaa caatatatgc ttcagtactt
     2341 aatgtcaata tcttgtatag atacatattt ataaactaat gtacaagttt aaaaaaagaa
     2401 agataatttt aatttatttt aaaataacaa tgttaataat catttttatc aaattttttc
     2461 ttgtttttct ccttgttttt atacattttt ttatccaatt caactattgt caattttaaa
     2521 tttcttttta ctgtatcaac accataacta aatgaaagat acttatactt agagaatact
     2581 tttaaaaaat tttctcttaa ggcttctagc tgtgaataaa cataattttt gtcaacatca
     2641 ctagagaata taacaataaa ttcatctcct cctaatcgta taatagaagt agaatttatt
     2701 aattctttat ttaaaagtga aacaaaatca cataaaatct tgtctcctac attatgacct
     2761 tcatagtcat ttatcatttt gaaattatct aagtcaatta gtacaatata atctcctata
     2821 aatatgtcaa atctatcatt taaatatttt ctattatatg ctccagttaa tgggtcagta
     2881 attgagtagt gaagatttct cttattttct tcatagagtt ttgttatatc attggccata
     2941 gtaattatgt aggttttttc atcaacatct actttgtatt ctaaaacatt ccaatagctt
     3001 gtagtatctt ttttaaactc taaaatccaa tttgaaattt tatcataagg ataatttttt
     3061 tcccaatcta attgaatatt gtgagaatcc gtaaaaaatt tagcaatatt atcagggagt
     3121 ttcttagcta tttctatatt agtcattcca agtggattat cttgcatata acttttaatt
     3181 aaatttttta aattatcatt tataaatata attctgtagt tagaatctct tataattaga
     3241 aatcctggaa aagttcttaa aaaaatttct ttaaacatat taatttctcc aaaataaaat
     3301 actttgtact agatttttgt taaatttttt attttattta catctacata cataccctgg
     3361 gcaatcgacc ttccatcaat tgcagaaagg ttacattgtg tatacataac tgtgacaatt
     3421 tgaccatctc gttttatgaa tctatataaa aatggttcaa ttttatttgt gtcaatcatg
     3481 tccaaacttt ttttataaac aaagtctaaa tcatctggat gaacaattgc tcttaaattt
     3541 ccgcccatct caccaaaaaa ctgttctttt gtataaccta taatatcaaa catttcttca
     3601 ttcatataag taataatcat atcaccaaat aaatcgtagc gaattatacc tacaggcaac
     3661 attgaataaa attgtgataa aatattactt tcatcaagat gtgtatttgt cattttaggt
     3721 attgaatatg attcaaattc atttatatag ccagcagttt taattaaatc caaatgtaat
     3781 tttgctaaga gtaatttatt ttctgaaatt atacaatttg cactaaagta gaaattgcta
     3841 tatttttgat gttcagaagc ttcatctgat aaaacggctt ctccactaat taataatgaa
     3901 tctgattcag tattatgtgg ggttatactt ttgtaaagaa tagaaaattt tttaccttta
     3961 atatgttttt caaaatgctc tattacttta ggaaaagatg taatttcagt tttgttgtaa
     4021 aaatcaaacc attgaatgtc ttcagtgaca ttagctctta gttttttcat atcttgcata
     4081 ataaaaaatc catcaaatat cttctctatt aaagattttc ctatatcaga atattttata
     4141 aacattttct ctgaattatt ctctttagat agtaattttt caaattcttt gcactccatg
     4201 ggttttgcat aataataacc ttgggcgata tcacaattta tacttttaat aaattctaca
     4261 tgttgttctg tttcaacacc ttcacatact gtaagcatcc caagagctct tgcaatgttt
     4321 attatagagt acaaaatggt tgtattttta aaatcattta aattatgaga taaaaatatc
     4381 ctatcaattt tgattatatc aaaaggtaga ttttgcaaca taccaaaaga tgaatatcca
     4441 gaaccaaaat cgtccattga tacagaaaaa ccataagaac gaagttcagc tagttgttga
     4501 ataattgtat ttgtattttc tattaatata ttttctgtta tttcaatgct aaaatttgat
     4561 gtagagacgc tgtacttttc agtaatacct tttagcatac ttggaaaatt agggttaaaa
     4621 aaatgaagac gagaaaagtt acaacaaatt ggaacaaaaa catcattgtt atcaatccat
     4681 cttcttatat ttttacagtt ctcttcaaat aaatgcaaat ctaattccgt tatcagacca
     4741 aactgttcaa ataaaggaat aaatttatct ggagtaagaa gtcctttaat agggtgtctc
     4801 catcttgcaa gtgcctcaca tccaactata gtattatttt ttatattata aagtggttgg
     4861 taaaatactt caatttgttt agtttgtaga acatgtgata tttctgataa gaactcctta
     4921 tcattttcta atttattgta aaaactatta tctttaaaat caaatagaat gtatctattt
     4981 ttaccttcac ttttagcctt ttttaaagca ctatacactt ggttgaaaag catcaaagta
     5041 gtcatgtttg gttcaccatt ccagatagtg ctgccgatac taaatgtaac attggagtat
     5101 atttcttttt cattaggaag tcttattttt aattctcggg cgctctctat aatagttgca
     5161 cccatattat ttaactcttt atttgataca tttggaagta caattaaaaa accttctcct
     5221 tttaaataag cgactattcc ctttgattct ggaataaagt gcaataggtt ttgagttaga
     5281 gtaattaata aattttctcc gactaggtat ccatatatat cattaaataa tttaaagtta
     5341 tcgatattta ataacatgat tcctatatgt atatttttcg aaatacagtc atcaatatgt
     5401 tggtacataa attctctgtt tggtatttta gaaaaaaaat ctatttcatt taaggttttt
     5461 aatttaaaat ttctactatc taattcctta gataatactt ctaccttttt atttaacatt
     5521 tttatataat tatgattttg catggtattc ctccataaga tactttaaat tttgatgaca
     5581 actgtattta tgctagaagt atttaaatgt taatttgtaa ataatttaaa tgctaaattt
     5641 taaataagta tttaaaatga atatacatta agttatttgc tccaatgcta caaatacaaa
     5701 tattttttag tttagtaata atattagata aaattagtta atgcttaaat tctagtatat
     5761 tgaaagattt cctttttgaa tgcaattata tcatattttt tcataaatag atagattgtg
     5821 agctgtatag ttagtaaggt agagtttttt tataattaat tttaagttta atgatttttc
     5881 aaaggcataa ttattttatt
//
LOCUS       DAYAKB010000140         5860 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.142, whole genome shotgun sequence.
ACCESSION   DAYAKB010000140 DAYAKB010000000
VERSION     DAYAKB010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5860
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.142"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(48..2354)
                     /locus_tag="ACGI3L_003598"
     CDS             complement(48..2354)
                     /locus_tag="ACGI3L_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9199277.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKILSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(2347..3141)
                     /locus_tag="ACGI3L_003599"
     CDS             complement(2347..3141)
                     /locus_tag="ACGI3L_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HFG9199278.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(3248..4606)
                     /locus_tag="ACGI3L_003600"
     CDS             complement(3248..4606)
                     /locus_tag="ACGI3L_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFG9199279.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
BASE COUNT         1869 a         1123 c          645 g         2223 t
ORIGIN      
        1 ttacaaaata atttaaattt acttgctttt atgcatctta ttatttatta taattgttta
       61 ttattatttt tcatacccat ataaactttt tcaaaagtca taggaagctc tcttaaacga
      121 actcctgtag cattaaatat tgcatttgct atagctggtg ctggtgtatg tataactatt
      181 tctcctaatg atttagcacc ataaggacct cctgggtcga aattctcagc aaaatctacc
      241 aatatatttc caacttcttt ttttgtagga actttatact gtaggaaact atctgttaat
      301 aatctaccat ctttatcaaa tatagggtct tcatacattg caaaccctat acccatcatc
      361 acaccacctt ctacttgtat tctagctaaa gttggattta taactgttcc acaatcaggt
      421 acacatgcaa aatttatgac tttatattca cctgtatttt tatctaattc tatctctgca
      481 aatcctgcta taaatggttt tatttttttc aacatgccaa aagattctgt tgcttccaaa
      541 actactggta catcatcact agcaaatcct attcctccaa cagattctct acccaattcc
      601 tctaatagaa caaacttgct attatcgttt ttaacaaaaa ccctgtcttt tcccaactct
      661 aaatcttctt ttttaaatcc tagctttgac tctgcaactg aaagtaatat atcttttaat
      721 ttatttgctg tctttattgt tgcatttcct gtaaccgttg tcgtacaaga agcaaatgct
      781 cctgtatcat agggacataa gtctgaatca cctgtataaa tagaaattct atctacagta
      841 gtatttaaag cttccgcagc aatttgagct tgaattgtat cagccccttg acctaagtca
      901 gcaagaccag ataatatttt atatgtgcca tcttcatcca ttcttatagt gactgttgcc
      961 atatctacac gcggtatacc agaaccatga tttgctactg ccatacctac tgctcttact
     1021 ttgttgtttc ctatatcttt acatggatat ttatcatccc aattaattaa tttctttccc
     1081 ttttctatac attgtctcag ctcacaactt aatatttcgt cttcagctgc ttttccattg
     1141 gtatacctat ctattatatt tttaattcta aattcaagtg ggtccattcc aatcttatgt
     1201 gccaattcat caatagcact atctattgca aatattccct gtgtagcacc ataccctcta
     1261 agtgctcctg ctggtaacct attagtatat actgttctag cattaaatct aacagcatca
     1321 atatcattat atattggtaa ggtattgtgt ccagattcgg aagaaacaga gacaccattc
     1381 ccaccataag cacctgtatt gtttaatgac tttagctcta ttgcttttaa atttccttct
     1441 ttatctgcac caactttaac atcaaaaaac atttcatgtc tactattaga acctacaaaa
     1501 gtttcacttc ttgtaaatac aaattttgct ggtctaccag ttttcatagt aacaaatgca
     1561 gtaaatatat ctgttgctgc tatattcttt cctccaaatc caccacctat tctaggttta
     1621 attactctta tttttgaaga cggtataccc aatacttttc taagtattct ctttacattg
     1681 tgtggtgatt gtaatgatga aactacaaca attctatcat ttatatcttt atatgaatat
     1741 gacctatgag tttccatcat gcaatgcgat tgactttggg ttttgtatga agattcaacc
     1801 acaaaatcac tttctttaag cttagcttca acatctccaa attcaaaaaa ttcttttgat
     1861 actatattat tttttgcatc caatccaaaa gggtatggct ctactatgtc tttttctgga
     1921 tgtataacaa cttcatttcc ttctgcttct cttgcatcaa acacaggctt taaaacctca
     1981 taatctacct ttatcatttt taaggcttta agtgctgttt tctcatcttc agcagccact
     2041 aaagctactt catctccaat aaatctaact gtatcttcaa gtaaaactct atcataaggt
     2101 gatgcttctg gttctgtttg acctggaaca caatatctga cctgtggtac atctttatac
     2161 gtataaatac ccacaacccc tggaattttt tcggcttttg atgtatctat attctttatc
     2221 ttagcatgag catgtggact tctaagtagt tttaatgtca aaacatcttt atgcataatg
     2281 aggtcttcag tatatagagg ttttcctgtg acaattgctg tactatctat ctttcttatc
     2341 cccttattaa tcattataca ttccctcctc aatagcatta tacatccttt taactaatgc
     2401 acttgccata tcctttctgt actctttact agctctcata ttacttccat aagtaagttc
     2461 cttactagca acaatagatg ccttatctat atctttttct ttatttaata tattactcgc
     2521 ttcaagtgct aatctagctt tttgaggtct tgccccaatt gctattttgt aagtatcatt
     2581 ttcttttagc attgctgaat ttaatacaga aaaatctcct gtgcattttc ttattgagtc
     2641 aaaaacagct attgcatctt tttttggtag tattacttcg accaatatat ccctacttaa
     2701 ttcactatcc aaaaactcac ttaactctag tattccttta ttgtataatc tcaccttcgc
     2761 tccaacaacc aaaagtgctg gtattaagtc agaaaagcca tactttgaaa atacacttgc
     2821 accaattcta gccccttgtc taaattgaac accaactata ttagaaacag cgcttgaaag
     2881 tattccacta cagtaatttt ttatagtttt atcaatttct aaacttctaa gtgaagtatc
     2941 tgcacctatc aaaatatttt ttttatcctc ttttatataa tttagattta tatcttttaa
     3001 atctatcgct gttcctatat ttttattact taattttata aatccacatc cacctaaaat
     3061 aacattattt tttttagaaa ttaaaatttt atatgcttct tctaaactct gtggaactga
     3121 atattccttt atagtaacca tcttatcccc ccatcattaa cttattaaaa cacaaaagtt
     3181 tttaataaat cttttattta tatttataat tgtagtatat ttaattcaca tatattaaac
     3241 ctttacatta taaactttta tttttatcct caaccttatc acttttattt ccaggaaatt
     3301 ttaccatata taaagcttga attattatgg ctaccattgc tcctgaaact acacttgaat
     3361 ctgcaagtaa tgtctctata aattttggaa atttttcaag aacttgagga gctaccatga
     3421 atccaatacc agaagccata gaaagaccta atatcatgct attttcttga ttaaatccat
     3481 ccatactaac aagtcttaaa ccagatgttg taagagttga aaatataacg agtgttgctc
     3541 ctccaaccac acagggagga attgttctta ttaaattagc taataaaggc gatattcctg
     3601 ccaaaaataa tccaattcct ccaatagcta gtacaaattt acttacaacc tttgtattgg
     3661 aaacgattgc agaattttgt ccaaacatcc ccattggagt tgcagaaaat aatgcaccta
     3721 ttgtagagag tactccattt cctaaaacag cagaagaaag ttcttcatct gttacttgtc
     3781 tattaagccc tcctaccgca gaaagtgtac aagcacccat tatatcagct atctcaacta
     3841 aatatattat tgaaaacatt acaacaactt caagtcttat atctagccca aaagcaagtg
     3901 gttttggaag tgcaaccaaa gtaaactcct gaattgaaga aaaatttact atacccaaaa
     3961 ttaatgataa aatgtatcca aaaattatgc taactaatat tgatgcatct ttaaataatc
     4021 cttttccata cttatttaat cctaatatca taagagatac agatattcca actataaaat
     4081 taattggatt cccaaaagtc tcattgccca tacccccagc taagtttttt atagctattg
     4141 gaaaaagtcc aagacccata catgcaacta ttgttcctga tacagctgga gtaaatataa
     4201 atcgtatttt tttaagacca aaaccaatta taattattac tataccagct attatttgag
     4261 agccaaataa tactggtagt ccatacttac ttgcaacaga taccccagct cctataaaca
     4321 tagctgtagc tcccattata actggtattc ctcctcctaa tttaaaacct ttaaacaaag
     4381 gtattggata taattgtaat aaagttgata atcctgcaaa aactaatgcg gcttgaatca
     4441 ataatgttga catcttatga ttaagtccag ctgcatttgc aatcaatatc gctggtaaac
     4501 aactacctat taccattgcc attaagtgtt gtaaccctaa aggtattgct tcctttagtg
     4561 gtggtattcc gtctaattca aattttgatg tactttttgc tttcataata aaaactcccg
     4621 ttacataaaa cttattgaat tatataaata cttaaaaatc taatatatta aattaatgat
     4681 gttcataaat atcaactata ctccaacata tatttaagtt tttagtctta aaaaacagat
     4741 gcaataaatt taattattaa caaatacacg tattctttaa ttttgtatac attatatacc
     4801 atgctttaca aatataagag tattatagct atgaattttt aattttttat agtaaattta
     4861 attcaattta aatctttcaa tcttaatcat tataagttat aagttttcat aagtatttac
     4921 atgtttcaag ttttaaacat ttacctataa acgctacttt atagatgtca cttcaaatcc
     4981 agtgacctca tactttcata tgagcgtaga ctatttcttc atcttcagca ttacctgcta
     5041 agagcaaccc gtttccacta tcaatcgctt atagtgtact ctctctcgag atagtcgttt
     5101 gaccttccta tttctaggct tggcgaccaa atgtccattt ttaagtactt aggctctcac
     5161 catataccat cctcactatt gtttctggtt ttcaccacat tcataaaagt ttctttctat
     5221 cttttattgt agttgcaagg ctttaggatt tactggtttt aaagttgtgt cctacataga
     5281 tttctctatg tacggggcca aaagtacaat ttatttaaca tactttgctt taccccctgt
     5341 aaataatatt atttactctt tcactgtttt tgttattaaa ttaattaaat atcaattaat
     5401 ctaagcataa aataattatt taatttaaac tcaaaatatt tatgaatatt ttataatata
     5461 attctcataa gacagaaaaa cttaataagc tatgtatctc agttgtacca atgtactctc
     5521 ctttactata tttgtatctg caacataaaa tatacaagtt tctatctatt tatagatata
     5581 tatatctata agcaaaatag taatattatt tttatagtaa aaattttatt catattacta
     5641 tttataattt ttatagagca attttagtgc caatatttgc atacatttgt atagtataaa
     5701 atttttatgt tctcattgat aaaattttac ttatttcaag cgttctatta gattttatca
     5761 tctaaatttt aggttttatt tttataaatt aattgtattt acataaaaaa aaagacctaa
     5821 aaacaaattt ttaacggtct tttctcaatt ttttattttc
//
LOCUS       DAYAKB010000141         5782 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.143, whole genome shotgun sequence.
ACCESSION   DAYAKB010000141 DAYAKB010000000
VERSION     DAYAKB010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5782
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.143"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            351..866
                     /locus_tag="ACGI3L_003601"
     CDS             351..866
                     /locus_tag="ACGI3L_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HFG9199280.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      1358..1462
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            1672..4146
                     /gene="gcvPA"
                     /locus_tag="ACGI3L_003602"
     CDS             1672..4146
                     /gene="gcvPA"
                     /locus_tag="ACGI3L_003602"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HFG9199281.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            4146..5603
                     /gene="gcvPB"
                     /locus_tag="ACGI3L_003603"
     CDS             4146..5603
                     /gene="gcvPB"
                     /locus_tag="ACGI3L_003603"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HFG9199282.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         2280 a          622 c         1048 g         1832 t
ORIGIN      
        1 actcccttca tccgcacttt acagtactta attgtactga aaaaaactgg ggttgctggc
       61 tttcggagtg ggctatcccg tttttatttt tttgtatata taatagattg gcactttagt
      121 ataaggtgct ttttttatag gcaaaaacag tacatttatt tctgttttat tatcattcat
      181 ctattagaat atactttagt taagaatgtg ttaataagca gtgttcacat tcttgataaa
      241 atgtggaata atatgtattt ttactaagac ggaaatgaaa taattaaacc attaaataat
      301 attataagat gatgaataag tagataaatc aaattttgta ggaggatatt atggaaaaat
      361 atatatggtt gtttccatta ctttttattt ttcatgatat ggaagagata ataggttttg
      421 gaatatggct taaaaaaaat aaatcaatgc ttgataagaa gtatccattt atcagtaaag
      481 tttatgaaaa ttatagtact gaaggcatgg catttgctgt gtttgaagaa tttattttat
      541 gcattatttt ctgtatactt acagttataa cagagaatca gtatgtatat ctactatggt
      601 taggtagttt tatagcatat accttacatt tggtaattca tatagggcag tcaatcataa
      661 taagaaaata tataccttca cttattacca gtatcatatg cttaccaata agcatttggt
      721 gtataagtaa gagtatttat atagttgatt gtgaaatgag tacaacaatt ctgtacagta
      781 taattggcat tataattgta gcattgaatt taaagtttgc acagtcgctg attggaaaat
      841 ttacaaagtg gatgtcaaac atataaattt tagtttattg gacagttcaa ggaatcagaa
      901 attggaattt tatagtatta atattttatg gtattaatat aatgtataaa attttatagc
      961 aatgtatttc ataagtataa agtgactaga attttaagaa atatacaaat tctataaaaa
     1021 ctaaataatt tcaagtatat tttaaaaatc ttatttttca caagtttaaa attgtaaacg
     1081 atttcatcaa gtctatgaat atacttttaa catgttatag taaatctcaa tataaattta
     1141 catttggttc tttgtgtgtt attttaataa taaattaagt gaaaatgtta ttttacatta
     1201 atatataata tctttgcata agagtgaata atataaaaga gaaataattg ataataaaaa
     1261 cttaacaaaa aaattaatac ataaaaaaaa ataaatataa tgtgttgaca tttaattgaa
     1321 atattcatac aataaaattg aaaataaata tttccaaatg agattagcga gagagtcctt
     1381 tatacgaaaa ggcgccgaag aagaaattta agaaatgcca atttttagag aagctttcag
     1441 gcaaaaatat cgctaattga tgggactctg gagagactta agttaagata ctataagtca
     1501 ccgaagaagc aaaataatat taaattatta aatctttcag gtatacaaac agggatatat
     1561 aggctaggat tattttccat gctgatatat ctttttttta tgaaaaagta caggaaataa
     1621 tatcaaagtt acttaaatac agtaggtcta attttctagg gagggttata tatgaatgaa
     1681 ttgaaaagag tatctttgta caatatacac aaagagcttg gagcaaaact tgttgaattt
     1741 gctggttggg aaatgccttt agaatatgag ggtataaata aagagcatga gaaggtcaga
     1801 aaaagtgcag gtatatttga tgtatctcat atgggagagg tacagataaa gggagcagag
     1861 tcagaaaaat ttatacaaaa cctagttaca aatgatataa gcgcattaaa gataaatgat
     1921 attatatata cacctatgtg ttatgaaaat ggtggagtag ttgatgattt attaatatat
     1981 aaatttggtg aagaagatta tttattagta ataaatgcag gtaatataga taaagatgta
     2041 gcatggataa taaaacaaag tgaaggatac aatgtagata taaaaaatat atctagtgaa
     2101 gtgagtcaat tagcaattca aggacctaaa gcagaagaaa ttcttcaaaa aatcacagat
     2161 atagacttaa actcaataaa attttataag tcaattccat caacaaaagt atgtggttgt
     2221 ccttgtttag tttcaagaac aggatatact ggggaagatg ggtttgagat atactgtaaa
     2281 aataaatatg tagaaataat ttggaatgaa gttctaaagg ttggaggaga agatatatgt
     2341 ccagctggtc taggttgtag ggatactttg agatttgaag cagctctacc tctatatgga
     2401 catgaaataa atgaacacat atctccaatt gaaggtggtt tatctatctt tgtgaaaaca
     2461 aataaagaat catttattgg caaatcaatt ttatcaaaag aaaaagaaag tggagctaaa
     2521 agaaagttag taggatttga aatgcaaggt aaaggaatgc ctagaaatgg atatgatata
     2581 aggattggtg ataaaacagt tggatttgta acaacaggat gtgcatctcc aacgacagga
     2641 aaaattttag gtatgggaat tatagattct gaatatgcaa aagtaggaaa tgaaataggt
     2701 atagcaatca gaaaaaaagt tgttcctgct gtgatagtta agaaaccttt ttataaaaaa
     2761 caatataaaa aagataatat tatattaaac aaagaaaata aattttcata tatacctgct
     2821 acaagtgaag ataaatcaaa aatgttaaaa gtagttggat taaattcagt tgatgaatta
     2881 ttttcagata taccagaaga agtaaaatta aaaagagatt taaatttgga aattggaaaa
     2941 tctgaattag aggtaagcaa aatagtaaaa agattgtcag aagaaaattt aagtttagaa
     3001 gacttgactt gttttcttgg tgctggtgca tatgaccatt atataccatc aattataaaa
     3061 catataactt caagatctga attttataca gcatataccc catatcaagc tgaaataagt
     3121 cagggaactt tacaagtagt ttttgaattt caatctatga ttgcagaaat tacaggtatg
     3181 gaaattgcaa atgcatcaat gtatgatgga gcaactgctg caatagaagc atgtataatg
     3241 gcaatgaatc agactagaaa aagtaaaata gtagtgtcaa aaactattca tcctgaaact
     3301 ctgtcagtat taagaactta cttacaatat aaagattgtg agatagtaga aattgacttt
     3361 tgtaatgaat atgggactac agatatagaa aaattaaaag cttctgtaga caaagataca
     3421 gcatgtgttc ttatacaaac tcctaatttc tttggaatta ttgaagaaat ggaagaaata
     3481 gaaaagataa ctcatgaaaa taaggctatg ttaattatga gtgtagaccc aatatcatta
     3541 ggagttttaa aaacaccagg tgagataggt gcagatattg ttgttggaga agctcaatca
     3601 cttggaaacc ctcttaattt tggaggtcct tatgtaggat ttttagctag caaatctaaa
     3661 tatactagaa aaatgccagg aagaatagtt gggcaaagtt tagatgtaga aggtaaaatt
     3721 gcatatgtat taactttaca aactagagaa cagcatgtaa gaagagaaaa agcaacttct
     3781 aatatatgtt caaatcaagc tttaaatgct cttgtagctt caatatatat ggctactatg
     3841 ggtaaagaag gatttaaaga ggttggtatg cagtctatga aaaaagcaca ttatacctac
     3901 aataaacttg tacaaactgg aaaatataag ccaatattta aaggtaagtt tttcaaagaa
     3961 tttgctgtac aaggaaatct taatatagaa actataaatg ataaactctt agaagaaaat
     4021 atattaggag gttataattt agaatacaat tatccagaat taaaaaattc aactttgctt
     4081 tgtgtgactg agaaaagaag caaagaggaa atagataagt tagttggaat aatggaggga
     4141 ttataatgaa agaatacaat agtttgttga tagatatatc taaaaaaggt aggaaagcat
     4201 actcacttcc aaagttagat atagatgata taaaaataga aaatatgatt gaccaagata
     4261 tggcaagaca aagtgagttg aatttgccag aagttggtga attagaatta gttagacatt
     4321 atacattatt atcaaataaa aactttggag ttgatacagg tttttatcct ttgggttctt
     4381 gtactatgaa atataatcct aaaataaatg aagatatggc agcacttcca aactttactg
     4441 gaatgcatcc ataccaatct tcggatacag ctcaaggttc tctttctttg atgtatgatt
     4501 tatcaagaag acttgcagaa attacaggta tggatgaagt tacactacaa ccttcagcag
     4561 gttctcatgg tgagtttaca gggcttatga ttataaaagc atatcatgaa aatagaggtg
     4621 accataagag aaccaaagtg ataattccag attctgcaca tggaacaaat ccagcaagtg
     4681 cagctatggc aaactttgat gtgattcaaa tagcatctga taaaaatgga gctgtagaca
     4741 taaatgcatt aaaagaggtt ttgaatgatg aagtagcagc tcttatgctt actaatccaa
     4801 gtactcttgg tttatttgaa aaaaatataa aagaaatagc tactcttgta catgaagcag
     4861 gaggactttt gtactatgat ggtgcaaaca tgaacgctat tatggggata acaagacctg
     4921 gagatatggg gtttgatgtg gttcatctta atcttcataa gactttttca actcctcatg
     4981 gaggtggagg tccaggagct ggtcctgttg gagttaaaaa agaattagta ccttttttac
     5041 caataccagt aattgaaaga aaagaagata agtatgtact aaattatgat agagaaaaat
     5101 ctattgggaa aattaaaaat ttctatggta attttggagt tcttgtaaga gcttacacat
     5161 atatactaac tatgggaagg gatggactta aagaggctag tgaaatggca gttttaaatg
     5221 ctaattatat aaaggaaagt ataaaagatg attatatttt gccaatagat accttgtgta
     5281 agcatgagtt tgtattaggt ggattgccaa gaggagaggc caatataaaa actatcgata
     5341 ttgcaaaaag actactagat tatggatacc atcctccaac aatgtacttt cctcttatta
     5401 taaatgaggc acttatgata gaacctacag aaagtgagag tatagagaca ttagatagtt
     5461 ttatagaagc tatgaaaagt gttgctaaag aggcaaagga agaaccagaa ctattgaaaa
     5521 ctgctccaca taatactttg gtcaaaagag tagatgatgc aagggcagta aagaaaccta
     5581 tactaacatg gtcacaaaga taaatagtta aaaagtagag atttaaagta taaagagaat
     5641 taaatttgta agaaaaagct atctaactta atctagttta gatagctttt ttgtatatta
     5701 gtatgtatgg tattttctat ataaagtttt aaattatatt agtgcttata tagaatattg
     5761 atatgatgat tatgtataga ta
//
LOCUS       DAYAKB010000142         5628 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.144, whole genome shotgun sequence.
ACCESSION   DAYAKB010000142 DAYAKB010000000
VERSION     DAYAKB010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5628
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.144"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..369
                     /locus_tag="ACGI3L_003604"
     CDS             <1..369
                     /locus_tag="ACGI3L_003604"
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HFG9199283.1"
                     /translation="ELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVSRENIMKDY
                     LKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEEYISVEAYL
                     YGEFNLNKEEIRKLRNQYLE"
     gene            381..2159
                     /locus_tag="ACGI3L_003605"
     CDS             381..2159
                     /locus_tag="ACGI3L_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9199284.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            2326..3243
                     /gene="pfkB"
                     /locus_tag="ACGI3L_003606"
     CDS             2326..3243
                     /gene="pfkB"
                     /locus_tag="ACGI3L_003606"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFG9199285.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     IFKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            3280..5199
                     /locus_tag="ACGI3L_003607"
     CDS             3280..5199
                     /locus_tag="ACGI3L_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFG9199286.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         2307 a          521 c         1029 g         1771 t
ORIGIN      
        1 gaacttataa gagactattc taatttacca atattaaatc attgtacagc tggtaaggat
       61 agaactggtg tggggagtgc tataattctt atgattttag gggtatcgag agagaatata
      121 atgaaagatt atctaaaaag taatgatttt gcagataaag agatagaaag atttatagaa
      181 tataagccta aatttaagga cattccaaaa gaaaatttga aatatatatt tggtgtaaat
      241 gaagagtata tgaaaactgc atttagaaga attgatgaag aatacattag tgtagaagca
      301 tatttatatg gagaatttaa tttaaataaa gaagaaataa gaaaattaag aaatcaatat
      361 ctagagtaaa aggtgagttt atgagtttaa atataacagc aagacagata aatataataa
      421 aaatattgtt aaattcaaaa gatacaatta gtggtattgc cttaagtcaa gagataggat
      481 gttcttcaaa aactatacaa aatgaaataa aggatattaa taaacaactt agaaatggta
      541 aaattttgtc aataagagga gttggttata aactagaagg aagttttgat gaggtaaatc
      601 taaatagcaa tctctatgat gatgtagata gagtagaata tataatcaga aaaatattaa
      661 ccttaagtaa tgaagaaaaa aatactataa aacttgaaga tttagccgat tctatgtatg
      721 taagtgtttc aacagtaaaa aatgatttaa aagaagtaaa aagaatgttg gaaaagtatt
      781 caatatcagt taaatctaag cataaacaag gtatatgtgt tttggaaagt gaagataaga
      841 tattaaattg tatagttgac ttaagcaata agagagataa tcaattgagt ttaaatgatt
      901 ttttaaatga tgatataaag gaaagaaaac tattaataaa aaaattatta ttagacatat
      961 taaatgaaaa tggattagta ttaactgata tagaatttaa gagtgtgtta aataatatat
     1021 tagttatgtt aagcagacat aagtataatg aaaaagaatt tatagagaat tatatagaaa
     1081 attataggag caaaagaagc tcaattttag aaaatgaaca aaacaaagaa attataataa
     1141 attcaataaa aacattttgt aaaaatttaa aattagctac atcaatagat ataagtaatg
     1201 ataaggtatt tgaagagttt ttgtataagc atattagtag tttatgtaaa aaaataaagt
     1261 taggtataaa tcaatcacct ataatggctc aagatataaa aataaaatat ccatttgctt
     1321 ttgaactagc taatatagct aaaaagacaa tagaaaaaga tttgaagata gaaattaatg
     1381 aagatgaagt tgcaaacata gctctacata taggaggagc agttgaaaga gcatcttata
     1441 ataataaaga taaggttttc aaaactataa tagtttgtac ttcaggcata ggcacatcaa
     1501 tgttaataaa agctaaatta gagaatatat ttaaggaaaa attagaaata ctaaagatta
     1561 ttccttcata cttagttgaa tatataaaag ttatagatgt tgattttgta atatctactg
     1621 ttcctattga agtaggagat gtgccagtaa taaatatatc tccaatttta agtgagaaag
     1681 aaattagatt aattgaaaaa tatatagaaa caggaaatat atacctagat ttagatataa
     1741 aaagcctgtt tgatagtgaa ttgtttttta ctgatttggt gtttaaaagg aaagaagaag
     1801 ttatagattt tatggcaagt aaacttgtac aaaagggcta tatagatgag gatatgaaaa
     1861 aatcttactt tgagagagaa aaaatagcaa caacagaaat agggaatatg gtaactatac
     1921 cacatggagc tattggaaaa atttttgata ataaaatagc aattggtata ttaaagaagc
     1981 ctatttcttg ggaaatatca gatgttcgtt taataataat gttagccctt gataaagata
     2041 aaatattaga ttatgaagta atattttcaa aaatatataa aagagtagat tctatagcaa
     2101 aagttataag tatatgtgaa aatagtagtt ttgaaaaatt tgtaaattta ttcaattaga
     2161 tgggtagtat tgtatataca cctgtaaatt tggataatat aaaactaaat aagataaaaa
     2221 cgataaattt ctcttttaat taagagaaat tttttgactt tcaaggatat taatataaag
     2281 ttaagatata aacataaagc aaataaataa aaaagaggtg gcaatatgat ttatacagtg
     2341 acattaaatc catcaataga ttatatagtt aagctagatg agctaaagac aggaagtaca
     2401 aatcgtgtaa aagaagaata cgtttatcca ggaggaaaag gtataaatgt atctcgcata
     2461 tttaaggaac ttggaaatga taatacatct ttaggtttta taagtggttt tactggagaa
     2521 tatataataa gaacattgga agaaaaagaa ttgaagacag attttataaa gataaaaagt
     2581 ggtttttcaa gaataaatgt aaaaataaag gcgttaaagg aaactgagat taatggacaa
     2641 ggtccaaata tagatgatga agacattgat actttatata aaaaacttga taagctaaat
     2701 caagatgata ttttaatatt ggcaggaagt ataccatcta ctttagatga aaaactatac
     2761 gaaaatataa tggctagatt agaaaaaaag aatataaaag ttgtagtaga tgcaactaaa
     2821 aatcttcttc ttaatgtttt aaaatataaa ccttttctaa ttaagcctaa taacgacgaa
     2881 ttagaagaac tatttggtgt taaattaaat tcaattgaag acatggtaaa atatgctaga
     2941 aggttaaagg aaatgggagc tataaatgtc ttggtatcaa tgggaaaaga tggagcattg
     3001 ttgattacag aggaagatga agtgcttata agtgatgttc caaaaggaaa agtaaaaaat
     3061 tctgtaggag caggtgattc aatggtagca ggatttatat ctgggtattt gaatactggg
     3121 aaatatgatt atgctcttaa attgggagca gcttcaggta gtgcaactgc tttttcatat
     3181 gacttagcca aaagagaata cattgataaa ttggtaaatg agatatctgt aaagcagttt
     3241 taaaatatta aaaaatatat agaaaggtaa ttaatattta tgaaaattat agatttatta
     3301 gatgaaaagt caattaagtt aaatttaaat tcaaaaacca aatcagaagc aatagaagaa
     3361 ttagtagatt tggtcgcaaa tagtggaaat ttaaatgata aagaaaacta caaaaaagca
     3421 attttggctc gtgaagaaat gagtacaaca ggaattggag aaggtgtagc tatacctcat
     3481 gctaaaaatt cttcagttac taaagcttgt atagcagcag cagtgtcaaa agaaggtata
     3541 gattatgaat cgtttgacgg aagtttatca aatctatttt ttatgatagc tgcaccagac
     3601 ggagctaaca atactcatct tgaagtatta tcaagattat ctacaatact tatggatgaa
     3661 gactttagaa ataaacttat aaattcaagc tctgaaaaag aatttaagga aataatagat
     3721 aaaaaggaaa gagaaaaatt cagtgaagaa tatcaagatg agaaagttac tgaaaaaaat
     3781 ataatagata ctaaagagaa tgatgctaat aagtatccta aggttttagc agtaacagca
     3841 tgtccaactg gaatagcaca tacatttatg gcagctgaaa gtttaaataa aatggcagaa
     3901 aacaaaggtg tatcaataaa agtagaaact aatggttcag caggtgttaa aaataagctt
     3961 acaaaagatg aaatagaaaa tgcaacatgt ataatagtgg cggcagataa aaatgttgag
     4021 atggctagat ttaatggtaa aaaagtcata aaaactaagg tggctgatgg tatacacaaa
     4081 gcggaagaac ttatagacaa ggctgtaaat ggagatgctc caatttacca tggaggagat
     4141 ggaagtcaca acgaatcaaa tgaagaaagt gaaagtggat ttagaaaagt atacaaacac
     4201 ttaatgaatg gtgtatctaa tatgttacca tttgttattg gtggagggat acttatagcg
     4261 atagcctttt tacttgatga ttatactatt aacccttcaa actttggttc aaatacacct
     4321 atagcagcat tttttaaagg aataggagat aaagcttttg gatttatgtt acctgtactt
     4381 gctggatata tagcatactc tatatctgat agaccagcgt ttgttgtagg atttgtagga
     4441 ggtgctctag caggtgatgg tggttcaggt tttttaggtg cactacttgc aggttttata
     4501 gcaggttatt tagtagaagg gcttaagaaa atatttagtg tactaccagc ttcattggaa
     4561 ggaataaaac cagtattgtt atacccttta cttggaacac ttttgatggg aattataatg
     4621 acatttttag taatacctcc agttacagca attaataatg caatggttgg atttttaaat
     4681 ggtttaggtg gaacttcaaa aatagtttta ggattagtat taggtggaat gatggctgtg
     4741 gatatgggtg gacctgtaaa taaagcagca tatgtatttg gagttgcatc acttgaatca
     4801 gggcagtttg aaataatggc agcagtaatg gctggtggta tggttccgcc acttgctata
     4861 gctcttgcaa ctacattttt taagaataga tttactaaag aagaaagaga ttctggtaaa
     4921 gttaattatg taatgggatt atcatttgtt actgaaggag ctataccttt tgcagctgga
     4981 gacccacttc atgttatacc agcttgtgtt ggaggttcag cagtggcagg agcacttagt
     5041 atgttgttca acgcagctct tcgtgcacct catggaggag tatttgttat accagtggtt
     5101 acccatccat ttgcatatat attagctata gctgtaggtg ctttggttgg aatgatgctt
     5161 ttagcattac ttaaaaaacc attaaatcaa gaagtatagc aattaaagga tattcaagaa
     5221 cttaaaatat gatgttttat aaaaattaat atattgctga attattttaa aataaggatt
     5281 ttatgaggct gttatataac gatttgtaat tgttatcttg acagtctttt atttttatat
     5341 aagtaaaata agtgtgtttt gctttatttg tatttaaatt gtttttaagt tagaatataa
     5401 agaaaattat atattatttt aatattcact cgaactagaa aataatattt gttgtatttt
     5461 tttgtatata aaatatattg taatattaaa aaaataatag taaactgatt gcataaaaat
     5521 gatttttata taaaatttaa gcagaagaat aaatttctaa cgaaattgga tatttcttct
     5581 gtaaatacat attcaaaaaa agaattataa gagtttagtc agcagtcg
//
LOCUS       DAYAKB010000143         5483 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.145, whole genome shotgun sequence.
ACCESSION   DAYAKB010000143 DAYAKB010000000
VERSION     DAYAKB010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.145"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..516
                     /locus_tag="ACGI3L_003608"
     CDS             <1..516
                     /locus_tag="ACGI3L_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HFG9199287.1"
                     /translation="GTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLD
                     QAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFD
                     GYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRT
                     VASGVVATIIE"
     gene            766..915
                     /gene="rpmG"
                     /locus_tag="ACGI3L_003609"
     CDS             766..915
                     /gene="rpmG"
                     /locus_tag="ACGI3L_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFG9199288.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            941..1162
                     /gene="secE"
                     /locus_tag="ACGI3L_003610"
     CDS             941..1162
                     /gene="secE"
                     /locus_tag="ACGI3L_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFG9199289.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            1182..1724
                     /gene="nusG"
                     /locus_tag="ACGI3L_003611"
     CDS             1182..1724
                     /gene="nusG"
                     /locus_tag="ACGI3L_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFG9199290.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1763..2188
                     /gene="rplK"
                     /locus_tag="ACGI3L_003612"
     CDS             1763..2188
                     /gene="rplK"
                     /locus_tag="ACGI3L_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFG9199291.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            2259..2957
                     /gene="rplA"
                     /locus_tag="ACGI3L_003613"
     CDS             2259..2957
                     /gene="rplA"
                     /locus_tag="ACGI3L_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFG9199292.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    3009..3137
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            3180..3686
                     /gene="rplJ"
                     /locus_tag="ACGI3L_003614"
     CDS             3180..3686
                     /gene="rplJ"
                     /locus_tag="ACGI3L_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFG9199293.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3744..4109
                     /gene="rplL"
                     /locus_tag="ACGI3L_003615"
     CDS             3744..4109
                     /gene="rplL"
                     /locus_tag="ACGI3L_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFG9199294.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4500..5288
                     /locus_tag="ACGI3L_003616"
     CDS             4500..5288
                     /locus_tag="ACGI3L_003616"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFG9199295.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
BASE COUNT         2216 a          648 c         1074 g         1545 t
ORIGIN      
        1 ggaacagttg caacaggaag agtggaaaga ggagtactaa aagtacaaga cgaagtagaa
       61 ttagtaggat taacagaagc accaagaaaa gtagtagtaa caggagtaga gatgttcaga
      121 aaattattag accaagcaca agcaggggat aatataggag cattattaag aggagtacaa
      181 agaaacgaga tagaaagagg acaagtacta gcaaagactg gatcagtaaa ggcacacaca
      241 aagtttacag cagaagtata tgtacttaaa aaagaagaag gtggaagaca tacaccattc
      301 tttgatggat atagaccaca attctatttc agaacaacag acgtaacagg agcttgtaag
      361 ttaccagaag gaatagagat ggtaatgcct ggagataacg taacaatgga agtagactta
      421 ataaactcaa tagttgtaga agagggatta agattctcaa taagagaagg tggaagaaca
      481 gtagcttcag gagttgttgc tacaataata gagtaattct ttactaaact gatggattaa
      541 aaggaataac aaaaagaggg gttatgctcc tcttttttta acatagaaat acaaaaacat
      601 tgacacagca taggattttg tgataactta tacaaggtaa tgattatagg aagttaataa
      661 tatcttgaat actgtagatt tttaataaat acatatttta aagatattat attcacatat
      721 attaacaata tatattattg tattacaaag ttggaggtgt atcagatgag agttaaagta
      781 actttagcat gtacagagtg taagcaaaga aactacaaca ctactaagaa taagaaaaat
      841 aatccagaca gaatagaatt acaaaaatat tgtagattct gtaaaaagca tacaactcat
      901 aaagaaacaa aatagttttt tataaggatg tgagtatgga atggctgccc aaaaaaatga
      961 cggtgcaaaa actaaaaaaa ggtttagttt gtttggatac ttaaaagaaa ctaaacaaga
     1021 attaaaaaga gttacatggc cgacaaaaaa ggaactgttt aaaaacacaa gtatagtttt
     1081 aactgtagtt atttcatgca ctatattagt atggggtata gacactatat tatctggtgc
     1141 actagcgtta ttactaaaat agacgaaaag aggtaagtta aatgtcagaa ttacaagaag
     1201 caagttggta tgtagttcat acctattcgg gacatgaaaa taaagttaaa gctacaattg
     1261 agaaagcagt taaaacaaga ggtatggaag actgcataag acaagtagtt gttccaacag
     1321 aagaagtagt ggaaactact aaaactggaa aagaaaaaac tagacaacgt aaagtttatc
     1381 caagttatgt tttggttaaa atgataataa ctgatgaatc ttggtatgta gtaagaaata
     1441 ctaagggagt tacaggtttc gttggacctg gttcaaaacc agtgccatta agtgaagacg
     1501 aagtcaaagc tatggggata gacacaacag accctaaagt agtaaatagc gatattgatt
     1561 ttgaaatagg agatacagta aaagtatctc aaggaccatt tagtggacaa ataggtaaca
     1621 tagaagaaat tgacttagaa aatagagaag tcaaagtatg cataaatgca tttggtaaaa
     1681 ggactctatt tgtaatagag cttgaaggta tagaaaaaat ctaatactat attatagaaa
     1741 aatctgagga ggtgcgctca aaatggctaa aaaagttata ggtcaaataa aattacaaat
     1801 acctgcagga aaggctactc cagcgccacc agttggacca gcattaggac aacatggtgt
     1861 taatataatg ggattcacaa aagaatttaa tgctaaaact gcagatcaag ctggaatgat
     1921 aataccagtt gttataactg tatatcaaga tagatcattc agttttataa caaaaactcc
     1981 accagctgca gttttaatta aaaaagcatt aaacttaaaa tcaggttctg gagaaccaaa
     2041 caagaaaaaa gttgctaaaa tgacttcagc tcaagtaaga gaaatagctg aattaaagat
     2101 gcctgactta aatgctgcat cagtagaagc tgctatgagt atgatagctg gtactgctag
     2161 aagcatgggt gttgtaatcg aagactaatt aaaagataca ctttttttta taaagtggga
     2221 ggctagaagc cgaaattaac cacgaggagg aaaataaaat ggctaaaaaa ggtaaaagat
     2281 atgcaggtgc attacaaaaa gtagatagaa ctaaatttta tgatgcatca gaagcattaa
     2341 cattagtttc agatatagct ggagctaaat ttgatgagac agtagaagca cacattaaat
     2401 taggtgttga ctcaagacat gctgaccaac aagtaagagg tgcagttgta ttacctcatg
     2461 gaactggtaa aacaaaaaga gttttagttt ttgctaaagg tgaaaaagct aaagaagctg
     2521 aacaagctgg tgctgacttt gtaggagctg aagaattagt tcaaaaaata caaggtgaaa
     2581 actggtttga ctttgatata gtagttgcta ctccagatat gatgggtgta gtaggtagat
     2641 taggtagagt attaggacct aaaggtttaa tgccaaaccc taaatcagga acagttacat
     2701 ttgatgtagc taaagctata gatgaaataa aagctggtaa agttgaatac agattagaca
     2761 aaactaacat aatacacgtt ccagtaggaa aagtatcatt tggtggagaa aaattaactg
     2821 aaaactttac tgcattaatg gatgctataa taaaagctaa accagctgct gctaaaggac
     2881 aatatttaag aagtataaca gtagcttctt caatgggacc tggagttaaa ataaacccag
     2941 caagaacagc tgaataataa aactgttgac acaggttgac aaaaatgtta ttatatcact
     3001 tgtcaatgta aaaaagaata gatttgccgt agatagtggg tgcgaaagct taatatcccg
     3061 ccgaggtttt agataaattg agattactaa agcttttgat gtctactttt ggcaacaaaa
     3121 gctttttata atgttgcggt aaatactaag cctatttggt gaaggaggtg cacatctata
     3181 tgagaaaagc tatagaaatt aaatcagaag ttgtttctga gatagttgaa aagttacaaa
     3241 aatcttctgc tgctgttgtt gtagattaca aaggattaac agttgaagaa gtaactgagt
     3301 taagaaaaca aatgagagaa gctggtgtag attacaaagt atacaaaaat actttagtta
     3361 gaagagcagc taaagaagtt ggtatagagc aatttaatga tgaattatta gttggaacta
     3421 atgccatagc atttggatat gatgatccag ttgctccagc tagaatatta aaaggattca
     3481 tggattctca tccaaaaatg aaattaaaga tgggtattgt ggaaggtgca ttctatgatg
     3541 aatctaagat tgttgaaatg gctaacatac catcaagaga agttcttatc gctaaattac
     3601 ttggtagctt aaaagctcca gtatcaaact tcgcatactt aatagatgca atagcgaaaa
     3661 aggcagaagg tcaagaagaa gcttaattgc ttaactaaaa aattataaat attaatttga
     3721 aataaaattc ggaggtgcta aaaatgacaa tagaacaaat attagaagct atagaaaata
     3781 tgaaagtttt agaattaaat gaattagtta aagctgctga agaaaaattc ggtgtatcag
     3841 cttcagctcc agtaatggta gctggtgcag ctgctggtgg accagctgct gaagaaaaaa
     3901 ctgagtttga tgtagtatta actgacgttg gttcttcaaa agttggagtt ataaaagcag
     3961 ttagagaaat aacaggatta ggattaaaag aagctaaaga agtagttgac aatgctccta
     4021 agacagttaa agaaggagct tctaaagaag aagctgatca aataaaagag aaattagaag
     4081 ctgctggagc taaagtagaa gttaagtagt ttctttaaaa agatacccat tgggtatctt
     4141 tttttattta taaaaaacta taaagaaagt atttggaatt ataaagaaag tatttttata
     4201 aaataaaaaa aatttatata atagtactaa attaagggta tcatatatgg tgtaatggta
     4261 ttttaattta acattattat caaattaaaa tataaacaat tgttgtaatg tctgtatata
     4321 aagtatataa ttaaactaaa atgtaaaatt ttacatttta gtttaaaaaa atacacgagt
     4381 gtttataaat aaaatgtaat aaataattaa ttaacaaata taaattttaa aataagttag
     4441 atatttagaa aaatcgaaat ttgtaggatt taaaggacat attcaaggag gagttaataa
     4501 tggaaaaatt acaaggaaaa attgcagtag ttactgcagc aacaaaaggt attggattag
     4561 catcagcaga gatattagca aaaaatggag caactgtgta cttagcagct cgttcagaag
     4621 aattagctaa tgaagttata aataaaataa gtgcagaagg tggttgtgct aagtttgttt
     4681 actttaatgc tcgtgaagaa gagaccttta cctcaatgat agaagaggta gttaaaaaag
     4741 aaggtaagat agatatactt gtaaacaatt ttggttcaac aaacccttct cttgacaaag
     4801 accttgtaac tggggataca gataatttct ttgacacagt aaatactaat ttaaaaagtg
     4861 tgtatttacc atgtaaagca gcaattcctc atatgataaa gaatggaaaa ggaagtatag
     4921 taaatatatc aagtataggt tcagtattac ctgatttatc tagaatagct tactgtgtat
     4981 caaaagcagc aatcaactca ttaactcaaa acatagctac acaatatgct aaagacaatg
     5041 ttagatgtaa tgctgtactt ccagggctta ttgcaactaa agcagcatta gacaatatgt
     5101 ctccagagtt cataaaagaa tttttaaagc atgttccttt aaatcgtata ggggaaccag
     5161 atgatatagc aaaagctgtt ctattctatg ctagtgatga ctcatcattt ataacagggg
     5221 atttacttga agttgcagga ggatttggtt tacctactcc acaatttgca gataatatat
     5281 taggataatt aaattactaa tatgcaatga aagcttatgc attagttata gtagaaatga
     5341 tatttttata aaggccatag atataattta tattggaaag gtttgaggtt caaaattcca
     5401 agttaaattt atttatggtc tttattttgt atattttaat aaattgtata tatttgtata
     5461 aatgtaatta tttacaatca ttt
//
LOCUS       DAYAKB010000144         5358 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.146, whole genome shotgun sequence.
ACCESSION   DAYAKB010000144 DAYAKB010000000
VERSION     DAYAKB010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.146"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(210..1394)
                     /locus_tag="ACGI3L_003617"
     CDS             complement(210..1394)
                     /locus_tag="ACGI3L_003617"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFG9199296.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPVFIDTKKENGFKLTKDELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1767..4118
                     /locus_tag="ACGI3L_003618"
     CDS             1767..4118
                     /locus_tag="ACGI3L_003618"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HFG9199297.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4140..4679
                     /gene="nrdG"
                     /locus_tag="ACGI3L_003619"
     CDS             4140..4679
                     /gene="nrdG"
                     /locus_tag="ACGI3L_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFG9199298.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2097 a          598 c          852 g         1811 t
ORIGIN      
        1 tttttgttat aataaattta gaatttaact tatatagttt aatttgataa tttgatgaaa
       61 aaaataaaag acttactgat ttttaaatct ataggtcttt tattttttat ctaacattta
      121 aattaagttg ttgaatatat cttatattac ttaccttata tattaattac cattaataca
      181 ttatatctaa ttactattca tctaaattat tatgccatta ttttatatac aaattctttt
      241 aatttatcta atccagataa gaaagtattt tcactgcaag cataggatat acgaatatat
      301 ttatccatac caaatgctat gccaggaaca actgcaacat tatattcttc taaaaattga
      361 ttacaaaatt ctatagaaaa actatcttta tattcaaatt tctcagatac tttagaaaga
      421 tctataaata tatagaatgc gccatttgga ttcacatatc ctacattatc aatagagtct
      481 agttttgatt taattaaatc tcttcttgat ttatatgttt taaccatatt gtctatgtca
      541 attgagcaat ctttcaaggc tccataggct atgtattgtg ctgttagact tgggtgagat
      601 ataagatgtc cttgtataga actcattgct ttagcaatcg ttttattaga tgcagtatat
      661 cctaatctta atccagtcat tgcagctgac ttagaaaaac catttatagt tattgttata
      721 tctttagctt cttcgcttaa tgatgcaatt gatgtaaatt caccagtgta gcatattttt
      781 tcatatattt catctgctaa aatatatatt ttattttgta tgcatacatc tactatttct
      841 attaattcat cttttgtata aacactacca gtaggatttg aaggattgtt tattacaaga
      901 atttttgttt tatctgttat agatttttca agttcatctt ttgttaactt aaatccattt
      961 tcttttttag tatcaataaa aactggaaca gcattaacta acttaaccat ttcaggataa
     1021 ctaacccaat aaggctttgg taataagact tcatctcctt cgtctgttaa agctagtaaa
     1081 gtatttgtta ttgagttttt tgctccactt gatacaacta tttcatctat tgaatagtta
     1141 cagttatttt cttcaataag ttttttacag atttcctctc taagtatttt taatcctgga
     1201 actaaatcat atttagtgta atctttattt aaagaatcaa taccataaga ttttgcgtta
     1261 ttaggtacat taaaatcggg ttctcctata ctaagattta ttactttaac tccattactt
     1321 tccatttctt taactttaga actaatacct attgtgtagg atggtgttat aaagtttagt
     1381 ctttttgata acataaaatg cctcctttta aattattatt tatattatac gacaaattta
     1441 aagaatttac ataaggaaat ttgtagatat atacattaat atatataata gcctacactt
     1501 tttgcctaaa attagtgtaa aaaaaagaga aaaaaatttt aactttcaaa gttgttagaa
     1561 acgctactgt tcaaaatatc cacatagtat ttgcaatgat ttgcgcaagt ttgactatta
     1621 tgtacaaatt tggtaatctt aatatagcaa ttattaagat aatcccttta acttagttga
     1681 aggggatttt tttagactta acatactaca tatagtggta tggggattaa taaaatacaa
     1741 tatatagtaa caggaggttt ttttaattgg ttgaattcgt aaaaaaaaga gatggaagag
     1801 taattccatt taatgaagat agaataacaa gagctatatt tttagcagca acgaatgttg
     1861 cagaaagaga aggaatagta cctgattata aattatctga gcaattaact caagaagtaa
     1921 taaagttttt aaatcataaa tactcagaat cagttccaag tgttgaagat atacaagatt
     1981 ctgtagttaa ggttcttata gaaactggcc atgcaaaaac tagtgaagaa tatataatat
     2041 acagaactga aagaagtaga ataagaaatt caaaaacaag attgatgaag gcaatagagg
     2101 aaattacctt tgaagatgca gaagatgctg atataaaaag agaaaatgca aatattaatg
     2161 gtaatacagc aatgggaact atgttacaat atggaagcac tgtatctaaa gaattttgta
     2221 aaacacatat attaaaacca gagcattctt ttgctcatga taatggagat atacacatac
     2281 atgatatgga ttttttaaat atgggaacat taacttgttg tcaaatagat gttaaaaaac
     2341 tattcaatgg tggattttca acaggacatg gctttttaag agagccacaa gatataataa
     2401 gttatggtgc attagctgca attgctatac aaagcaatca aaacgatcaa catggaggtc
     2461 aaagtatacc atttttcgat tatggattgg ctgaaggtgt atataagaca tttaagaaat
     2521 tctacatagg aaatttagct aaagcattga agttatttaa aggaattgaa aataatgatg
     2581 tgataaagaa catagtatat aatacagaga aagaaacaaa tcaaaaagtt ggtcttaaga
     2641 gagatgaatt gtatctaaac ttagaaaaag agaaattaat acagactttt gatatagatg
     2701 atgaacttgt aaataagatg caaaactttg catttgaaga atcgtataga gaaactgata
     2761 aaaaaacata tcaatctatg gaagcattta tacacaatct aaatacaatg cactctagag
     2821 caggtgcaca ggtaccattt tcaagtgtaa acttcggaac agatacttct gaagaaggaa
     2881 gaatggtaac taagaatctt ctattatctc aagaaagagg tttaggtaat ggagagacac
     2941 caatttttcc aattttaata tttaaggtca aagaaggcat aaatttaaat cctgaagacc
     3001 ctaattatga tttatttaaa ttatcatgca gagtatcagc taaaagacta ttccctaatt
     3061 ttagcttttt agatgcgcct tttaatgcaa aatattataa aaaaggtgaa ccagatacag
     3121 aggctacata tatgggttgt agaacaagag tacttagtaa tgtgtgtggt tcagaaacag
     3181 ttagtggtag aggaaacata tcttttacta cagtaaattt accaagattg ggtataaaac
     3241 atggtattat aaataatgaa aaggctaatt tagatggttt ctttgaagaa ttagatgaga
     3301 agataaactt aattatagaa caattattgg agcgccttga ggtacaagga aataaaaaga
     3361 tgaagaattt tccattctta atggggcaag gtgtatggaa aggttctgat gatttaggac
     3421 cagaagatac actaaaagaa gtaataaaac aaggaacatt gacaattgga tttataggtt
     3481 tagcagagtg ccttattgct cttataggta aacatcatgg agaaagtaaa gaagctcaag
     3541 aattaggatt aaaaatagtg tcacatatga gacataaaat ggatgaagca acggacaaat
     3601 ataaattaaa tttctcctta atgggtactc cagcagaagg tctttcaggt aggtttacta
     3661 aaatagataa aaaagtttat ggagaaatta aaggtatcac agataaagaa tattatacta
     3721 attcattcca tgtaccagtt tattacaata taagtgcata tgataaaatt gagatagaag
     3781 ctccatacca tgaattgact aatgcaggtc atataacata tgtagagtta gatggagatc
     3841 catctgataa tttagaagct tttgaaactg ttataaaagc tatgaaagat ttgggtatag
     3901 gatatggaag tataaatcat cctgtagata gagacccaat atgcggtttt tcaggtgtaa
     3961 taacaagtaa tatatgccct gtatgtggaa gaaatgaaga tgaaagtgac atcaaattcg
     4021 aaagaataag aagaataaca ggatacttag ttggtacagt tgatagattt aataatgcta
     4081 aaaaagcaga agtaagagat agagtaaaac atagatagtt ttatttgggg gaataagtta
     4141 tgaaaataag aatgtcatct actataagtt atgacagcat agttgatgga ccaggattaa
     4201 gaatggtaat atggactcaa ggatgtattc ataattgtaa agagtgccat aatcctcaga
     4261 cacatgattt atgtggagga ttttatatgg atacagaaga aattataaat aaagtcaaat
     4321 cattgaaatt acaaaaaggc attacgctat caggaggaga accattttta caaccagaac
     4381 cattagaaga aatagcaaga gaagctaaaa taaatgggtt agatgtatgg tcatatactg
     4441 gatttacgtt tgaacaactg ttagataaaa aaaatagagc gtattttaaa aatttaaatt
     4501 tactaaagca aattgatatt ttagtggatg gaaaatttat agctgaaaaa aaagatataa
     4561 gcttaaagtt tagagggtca tcaaatcaaa ggataattga tgttcaaaaa agtttgaaat
     4621 ataaaaaagt gtttttggtt gagcaatata tgaaggatga tttatctata gcagaataaa
     4681 atataaataa acaggattaa atatatgcat atatttaatc ctgtttattt tcatataata
     4741 tttcaagctt gtataatgta acaattaaac caaaagactc attgtatatt tgaaattaag
     4801 ttttttatag tttataggtg ttttatgtgg attacgaatg atatagtatt gatacattat
     4861 ttaatagatt cttatgccaa gaaacaatta atttatagaa attcttaatt gttacaatat
     4921 aaatatctag ataagttata agatactgat aaataattta taaagtttat taatctaata
     4981 ttgtgtgtga atattaagtg gtcaagtagt ctaaaaaatg aaaaagattt aaaaaagtgt
     5041 tttaactaaa cacataagtg ttaaattcat gtataagtat aggttagata cataagaaat
     5101 aattatgtaa tatctatctt tgtaaaaaaa tattaaattt tgtaatttgt ggataaatat
     5161 gtttataatg tggataatat ttaatgtaat aagttaaagc aatatgaatc aactgtttat
     5221 aatgtggata atattataaa tgtatgaata attgcagtat ttaaaaacaa aaaaagttaa
     5281 aaaagttgtt gactctaaaa gaaaaagttg gtatagtaat acttgtcctc aagaaaaggg
     5341 caaacaaata aagcataa
//
LOCUS       DAYAKB010000145         5046 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.148, whole genome shotgun sequence.
ACCESSION   DAYAKB010000145 DAYAKB010000000
VERSION     DAYAKB010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5046
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.148"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            653..4795
                     /locus_tag="ACGI3L_003620"
     CDS             653..4795
                     /locus_tag="ACGI3L_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HFG9199299.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTSPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIVNPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NISTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNI
                     AEITSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
BASE COUNT         1952 a          729 c          839 g         1526 t
ORIGIN      
        1 agtttacata ataaaaataa agtcaactaa aattattgat tttagattaa agtaccggat
       61 taagcattta agtagatttt aagcttgatt tgattagaaa ggtacaaact atcaccgaaa
      121 aaaattaaac ccatttaaaa agcaatataa aagcttgtta tttttgagaa aaatagaccc
      181 tctaaactca attagattaa aaataaaata cagaaaatta tatctctaaa tatcttaaat
      241 aattaagttt aaattttacg atattttgtt tgatgattta taatataaaa gcatactctt
      301 aatcttcaaa atttaaaaag agtaaaaaat aacaaaaaaa tcactgacat ttcactgaca
      361 aattgtaatt ttgttattat aaatacattg aaaatacttg attattgaaa aatggcataa
      421 aataatacat tttatgccat ttgctattat ttgatagttt ttaacttatg acataagata
      481 ttttttaaca tatacaataa aatataaaaa aattgatatt gcaaataaaa aaaaatacat
      541 attagatgtt atagaaaaaa agcgcactta taggcttaaa atgtcacata aaagagtttt
      601 aaagaataat atattatgaa cacaaatttt gtaatcacaa aggagtgata atatggcaac
      661 agtatcagga caaatagttt ttgatagaaa tagaagtgct accattgatt ctggagactc
      721 aggaatagcc aatataccag ttgtattaca agatatagca actggagtta gacttgtggt
      781 tctcacagat gcatcaggaa attatgtttt tactaatgtt ccaaatggta actatagaat
      841 tgtagaagct tttggaacta caggaggagt accaacacca ggaaattttg caacagcgat
      901 agtaggtcca gttccaattg cagaaatgcc acctattagt tctgtgacaa gtcctcctat
      961 tggttcaaca aacttagatg gtacaacacc taacacacta ttaataacag tagcaggttc
     1021 agatataaca aatcaaaata tattaaatgg gcctgtgatt tatacaccta tagagaatat
     1081 attggattct tgcgtatctg tatctaatat aaaccttatt acagatgcag ataacggaac
     1141 attcggtttt tttccaccag gtacaccaag taatacagga cctgaaatag aaccttaccc
     1201 aaatgtgacg ccagatttta cgtatgttgt accagaccca actaagttta cacctttaga
     1261 tggagaatat acagtacaaa atattatgac aaatgcaatg agtaatgtta taggagcttg
     1321 gtggcgtatt gctgaccata ctacaggaaa tgaaacagga agaatgatgg tggtaaatgg
     1381 ttttaatcct ggagctgtat tttttaaatc aacagtacaa gttacaccta acactaatta
     1441 tttatttagc acttggattt taaacctttt taaggtaaca ggatatccac caccacagct
     1501 aggtgtaaga atatttgacc aaaataataa tatactatat caagcaacat taggagctca
     1561 aattccagtt aatacaaacg caccagaatg gaaagaagta ggtactgtga ttaattctca
     1621 aaataataat caacttacag tagaattttt tagtgaagga gaaagcgcca ttggaaatga
     1681 ctatgctata gatgatgttt ctttaagaga aatagctgtt ccaactttta ctccaataaa
     1741 aacaagtaac acagaaactg ctaatgtagg tgatataatc acatatacag ttacattaga
     1801 taatacttgt gatagccctt taactaatgt attttttagg gatttaattc caaatggttt
     1861 agagtttata cctggaactg taacggttga tggagtatct gtaccaggag tagaccccaa
     1921 tacaggtttc ccacttccag atattggagg aggaacaggg gttgaagtaa cttttgatgt
     1981 tgtggttgaa agtattccta acccaaatcc tactaataat atagctacta tagattactc
     2041 ctatacacct gtagaaggcg gtataccaaa tgatttttca gtagattcta atccagttcc
     2101 tgttgaagta atctcagcag atattgaagt tacaaaatta tctgaaccta ctatagtgaa
     2161 tccaggagag gaattaatat acactataaa agtagtaaat aatggaccat tcccatctga
     2221 aaatgtggtt ttaacagatg atgtaccagc ttctattgta aatccagagt attcattaga
     2281 tggaggagta acttttcaac catggactgg aagtttaaat atagggacat tagaagtagg
     2341 agagacaaga gttattataa ttaggggtat tgtaaatcca tcaacagtag gaattataac
     2401 aaatacagct gtagtatctt caactacagc agacccaaac cttaataata atacatctac
     2461 aatagagaca gaagtgaatt tattagcaga tattttagta atgaaaacag cagaacctaa
     2521 ttcagctgtt ccaggtactt tattgagata tactattcaa gtagaaaact taggaccagc
     2581 aaatgctgaa aatgtaatat taaatgatga tattccagct tctattataa atccagaata
     2641 ttcattggat ggaggagcaa gttttcaacc atggaatgga agtcttaata taggaacttt
     2701 aaactctgga atttcattaa cagttttaat tcaaggaaca gttagtttaa attcttcaga
     2761 atatatagta aatacagcaa cagtttcttc aactacacct gacccagatt taagcaacaa
     2821 tatatctacc attattacac cagttaaccc acaagcaggt atttctatta taaaagtagc
     2881 tgacgaggat gtagctgttc caggagaaga atttgtatat acaattgaaa tttttaatga
     2941 aggaccatct aatgctacga atgtagtttt aacagatgat ataccagatg ttattttaaa
     3001 tccagaatat tcattggatg gaggagcaac tttccaacca tggactggaa gtcttaatat
     3061 aggtacagtt gcaccagggc aattaataag aattatcata aagggattag taagttcaac
     3121 tgctacagga gatattacta atacagcaga agtaagtgca gatgtaccag aaccagttac
     3181 ggattcatca acagtgacaa ctcctatagt tccatcagca gatatagaag taataaaaac
     3241 tagcaatatg gatacagcag ttccaggaga aactttcagt tatactataa cagttacaaa
     3301 tttaggacca tctgctgcac aaagtatcgt tttgacagat gatataccag atgttatttt
     3361 aaatccagag tattcattgg atggaggagt aactttccaa ccatggaatg gaaatcttag
     3421 tataggcact ttggatgctg gagaaataag aagtattata ataagaggaa cagtgagcca
     3481 gacagcagta ggtacaatta taaatacagc aacaataagt tcaactacac ctgacccaaa
     3541 tccagataat aatacttcaa cagatgaaac agatataagt ccattagcag atatttctgt
     3601 gataaaaggc aacgaaccag ttgctatacc agggggaaga tttatttatg gaattgaaat
     3661 tgcaaatgca ggaccatctt ttgcagagaa cgtaacttta acagataata taccagcttc
     3721 tattttaaat ccagagtact caatagataa tggagtgact ttccaaccat ggaatggaag
     3781 ccttaatata ggtactttag atgctggaga gataagaaat atcataataa ggggaacagt
     3841 aagtcaaaca gcaataggca caattataaa tacagcaaca gtaagttcaa ctacacctga
     3901 cccaaatcta aataacaata tttcaacatc agaagcagag gtaagttcat cagcagatat
     3961 ttctgtagta aaacgaagca atcagactgt tgttgtacca ggagatgtac tagactatac
     4021 aattgaggtg agaaatgcag gaccgtctac tgctcagaac gtaactttaa cagataatat
     4081 accagcttct attttaagtc cagaatattc aatagataat ggagtgactt ttcaaccatg
     4141 gaatggaagt cttagtatag gcactttaga tgctggagag ataagaaata ttataataag
     4201 gggaatagta agtcaaacag caataggtac aattataaat acagcaacag taagttcaac
     4261 tacacctgac ccaaatccag ataataatac ttcaacatca gaaatagata taagttcatc
     4321 agcagatatt tctgtaataa aattagcaaa taaaacagaa gcatgtgtag gagagcaaat
     4381 agattttgta atagtagtat caaatgcagg accagaaaat gctcaaaatg ttactttaat
     4441 agacaatgtt tcagataagc ttaagaaagc agtattttca cttgatagag gtgtaagttt
     4501 ccaaccatgg actggaagtc ttaatatagg tacactacca gctggaactt taagagtgat
     4561 tatattaaga ggaattataa aatcaacatg tcttgataga ttaacaaata ttgcagaaat
     4621 tacttcaaca acaccagatt caaaccttaa caataatata tcaagagtgc aagtagaaat
     4681 aaaacaatgt tgttgtaatg attgctgttg taacaactgt agtaattgtt gttgcaatga
     4741 ttgtggttgt aaagattgtt gctgtaattg ttgtaaaaat gacttttggt gttgatttta
     4801 taaaataatt ttgtatacct taaattaaac tgaaataaaa aataaattca catatgagta
     4861 aaatatttta taaatattaa taaattttct atctttgata tggaccacat tcgtaatact
     4921 agttattaaa tgaagtggtc ctttttaatt cattaaaatt atttattcta attaaatttt
     4981 aaatgtatta aataatttta attttttata aaaaatattc atatgttatt tatattaaag
     5041 tttaga
//
LOCUS       DAYAKB010000146         5040 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.149, whole genome shotgun sequence.
ACCESSION   DAYAKB010000146 DAYAKB010000000
VERSION     DAYAKB010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.149"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            634..864
                     /locus_tag="ACGI3L_003621"
     CDS             634..864
                     /locus_tag="ACGI3L_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9199300.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            857..1438
                     /locus_tag="ACGI3L_003622"
     CDS             857..1438
                     /locus_tag="ACGI3L_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9199301.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(2017..2694)
                     /locus_tag="ACGI3L_003623"
     CDS             complement(2017..2694)
                     /locus_tag="ACGI3L_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9199302.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(2883..4247)
                     /locus_tag="ACGI3L_003624"
     CDS             complement(2883..4247)
                     /locus_tag="ACGI3L_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9199303.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            4375..4896
                     /locus_tag="ACGI3L_003625"
     CDS             4375..4896
                     /locus_tag="ACGI3L_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9199304.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         1909 a          662 c          804 g         1665 t
ORIGIN      
        1 taaagataaa cttcaatatg ggtttaactt gtggttaata gagtaagaat gtaaatagag
       61 ataaacttca atatgagctt aacttgtgat taatagagta agagtgtaaa tagagataaa
      121 cttcaatatg ggattaactt gtgattaata gagtaagagt gtaactaaag ataaacttca
      181 atatgagctt aacctatgat taatagagta agaatgtaaa tagagataaa cttcaatatg
      241 ggtttaacct gtggttaata gagtagggtg taactaaaga taaacttcaa tatgagttta
      301 acttgtggct aatagaataa gattgtgaat aaagttatag ttttagatgg gtattaacct
      361 gttactaata gaatatgatt aggtgtaaaa ttatagagct gcataagaaa atattataga
      421 tatattaaat attagataat aaatatttat atagatacac aaaagaaaag gcgatatgaa
      481 gctaaactta atgacttcat atcgtttttt atttgaaact cctttgtatt tagagtgtga
      541 tttttaatat tgaggtttta tgtgattaag tcacagataa aaagtaagta tcttgatata
      601 attcttatag attaataata tagggaggtt attatgtcta ataaaaaaaa gaagtatgca
      661 aatattttag caaatgagtg cgttgcttgt ggtagctgta taaaagcatg tccaagaagt
      721 gctatctcag ttccatgtgg cattagtgca aaaattaata gagatttatg tgttggatgt
      781 gggatttgtg aaaagatatg tccagcatct gtaattgaga ttataacaat attaaaagag
      841 gaagaaggta agtgtcatga ataataaaaa acattggtat gactatttat ggattttttc
      901 ttcaatatat ttgatattgg gatttgtaaa tattattttc gcttggattg ggctaatttg
      961 tttctttgtt ccactagcta tttctattgt taagggaaat aaagcttact gtaataagta
     1021 ttgtggaaga gggcaactgt ttaatttgct tggaaataaa ttgaagctgt caagaaatag
     1081 agatattcct aaatttatta gaagtaagtg gtttagatat gggtttttga cattttttat
     1141 ggtaatgttt gccaatatgc ttttttcaac ttatttagtg tttgaaggaa gtagaaattt
     1201 taaagaagta gtgactttgt tgtggactat aaaaatgcct tggcaatggg cgtatcatgg
     1261 aactttagtt tcaccttggg tggtacagtt tgcatttggt ttttatagtg ttatgcttac
     1321 atcaactgtt cttggtttga ttactatgat attgtttaaa cctcgttcat ggtgtgttta
     1381 ttgccctatg ggtactatga ctcagatgat atgtaaggca aagagtaagt ctgtatagaa
     1441 aggccttatg tgatatttac agttttgttc aagtagagat gagtagtagg tttgaatata
     1501 tatgacaaat atatgagtat aggggcatag atttagtttg tgtaaggtaa actgatttat
     1561 gcttcttttt tatgtcttag attattggct aagtggaaac aatgaattta gatattaaga
     1621 attattcagt tatttgaaga aaatagaata ataattaaca ttatattaat ggatattcat
     1681 tacatataag ccagttaata gcaagattta tttaatatga tataggtcaa gtatttaaac
     1741 taaataaggt catgacaatt aatataagta tagatataaa aagattagaa gttataactt
     1801 ataaaaggta ttctatataa atagtatggg gaaaatagtc aaattaactt attagaaaca
     1861 aaaaatatac ataaaaaata aatgtaaata tcaaataaga tactatatca aaatagatat
     1921 aagtatcttt tttattattg aaattatgaa aatatatttg attttacaca aaaaagagtg
     1981 cctcatgaac taaaaagttc attttgagac acacttttac agtgtcaaag aacgaagttt
     2041 atccttatcc aataccttta taccaccacg agataaagac acaatacctt ctctagcaaa
     2101 atatttcaac attctcgata caacttctct ggcactaccc atatacttag caatttgctc
     2161 atgagtcata tttatagtgc tactgccatt tttagctatc tcatcaatta aaaaagatgc
     2221 caaacgctta tcaaaactca taaaaagaat ttgttgcata gcccacataa catcagaaaa
     2281 acgttcagta gctaatttat atgaaaataa ctctgcatga atattttctg tagataattt
     2341 tgcaaaaaca gaggaactaa tctgtataat atcgcagtcc gtttcagcat ctacatagac
     2401 atcaaaagtt attgttttta gaatacagga agctgataaa atacatacat ctccatcatc
     2461 aagtcggaac agtgtaacct ctcgaccttc atctgaaagt atgtatgtac gcactgttcc
     2521 agattttata atcaaaatac caatacagtc actatcacca caatgtactg gattcccttt
     2581 tttgtaatgc gaggtatttg ctgaagaaat taataattct ttttgtaagt cagtaagttt
     2641 atcccaaaaa ggcaagctat gtgtaagtat atcaatttca ttttgtgaaa tcatacaata
     2701 tctcctttct taaattgtta taatcccatg atacaagtga atagataaat tgacaagtag
     2761 tttgttaaga ggattattta gtcagatagt aatagtatga tttatgtaga aaaaatatga
     2821 taatatatat tcttgctatt aatgagaaag taatatgttt tgatgatagt aggtttgtat
     2881 aactaatgca taccgtttat ttttaaaaga ttaagttcct tatgtaacct tatagacata
     2941 aaaccagcaa ttatagcagc catcaaatca gctattggtt gtgcatataa gataccattt
     3001 aacccataga atacaggaat aatcaaaatt atagggataa aacagacacc ttgtctacac
     3061 atacctaaaa atccaccttc ctttgctttt cctagtgcga ggaataatgt agaatacact
     3121 gtatagaatc caaatagcat aaatgaaaac ccatttgccc taagagcttt actaccattt
     3181 tctattaata aaatgtcacc acttgtaaat tgtgaaatta tagattttgg gaagagtatc
     3241 aatataagac caagcactac acaaaatact gtagtccata atatggaagt ttttattgct
     3301 atatgtaatc tatcgtagtt ctttgaacca aaattataac cagcaattgg ttggaaacct
     3361 tttataaaac caaatacaac aagactacct aaagacgtta ttcgtgttac agcacccatt
     3421 ccagctatca cagaatcacc atactttgta gcctccatat tagttaatgt aatagcaaga
     3481 ctagtcaata attgaaatat taaggtaggt atgccaattt ttaggatttc tgaaaaaatt
     3541 tcttttgaaa aacagcattc gttaattcta aaactaaata tacttttctt gcttaaaata
     3601 tatcctacat aaacaagtgt tgaagcaatc tgtgagatag ctgttgcaat agaagcaccc
     3661 cttaccccca gaccaaaagt ataaatgaat atcgggtcta aaatcatatt aagcaaagca
     3721 cctaataaca tagcacacat agttgtttta gcagctcctt cacttgtgac aatattagtc
     3781 atagtgacat tgaatatatt aaaaatagat gacacgacat aaatgctagc ataagatatt
     3841 gcataaggca taatactttt tgtagctcct aacaatttta aaattggatt gagaaaaatc
     3901 ataatcacaa taataactaa tgtacccact ataatactac tgtaaataga tgtacttacc
     3961 acttttcctg ctttttcatt atcaccatgg cctaaaagtc tggcaacata tgaagcagct
     4021 ccatttccaa acaataatcc taatcccaca acaagctgac ctaatggaaa tgcaacggat
     4081 atagctccca tttgacttgt tccaagtcca cccacaaagt atgcatcaac caaattgtat
     4141 aatgcagtta tcatcatacc tatcatggta ggtaatccca tagataacaa tgcttttgag
     4201 attggggcag accctaataa ttcaattctt ttgttacttt ctttcatact taacactcct
     4261 cttctattga cattaagtct aaattataat actataaatt atagtaagta tggaaaatag
     4321 tactataatt tatagtattt gtcaatagta agaaaactaa aggagatgat ttttatggct
     4381 acaatagatt taattgtatt gggaatagta aagcaacaac ccaagagtgc ttatgatatt
     4441 caaaaggcag tggaatacag gaatatatca cgttgggtta aaataagtac accatcaatt
     4501 tataaaaaag taattcaatt agaacaaaag ggatatattg aaagtaaaac tgtgaagaat
     4561 ggaaaaatgc cagaaaaagc agtttattca ttaactgaat taggtgagac acatttttta
     4621 gatttaatgt ttgatacatc tagcaaacca ataaatattc ttttagattt taatgctgtt
     4681 atagtaaatt taaatagcct tacaccagaa aaacagaaat tatgtctcaa taatattgaa
     4741 gagaatgttc aagagttaaa gaaaactatt gaggaaaata taagtataaa gacagaagta
     4801 ccagacacag caaaagcagt gttggagcaa cagttggtgc tagcacaagc attggaaacc
     4861 tggataaatt ctttaaaaga taatatggga aattagaatt agagaagcta acttaataat
     4921 cattaaacaa aaaccagcat atttaataat gagatattag aaaaaataaa acaaatgata
     4981 taaactgaaa agtatattta aaataaagct cacttaattg agggagaatg ttaaactttt
//
LOCUS       DAYAKB010000147         5033 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.150, whole genome shotgun sequence.
ACCESSION   DAYAKB010000147 DAYAKB010000000
VERSION     DAYAKB010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.150"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1188
                     /locus_tag="ACGI3L_003626"
     CDS             <1..1188
                     /locus_tag="ACGI3L_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HFG9199305.1"
                     /translation="FFSASETALMSLSKIRIRYMQDEGVKGAKLVSSLIENPNKLLSS
                     ILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVMTVLVLIFGEITPKTIAANNSEK
                     VSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGITNKGAKSFITEEELKTMVNVSH
                     EEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVAIDMEDSYDEIIQVFKTEKLSRM
                     PVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYMREPFFTYEFKKITQLLEEMKLE
                     KSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYDEEEDEIQVIKEDEYIVDGSTKI
                     GDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEVIEVDNIRFCIESIEKNRIKKIR
                     IYT"
     gene            1337..2389
                     /gene="ytvI"
                     /locus_tag="ACGI3L_003627"
     CDS             1337..2389
                     /gene="ytvI"
                     /locus_tag="ACGI3L_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HFG9199306.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            2479..3705
                     /gene="pepT"
                     /locus_tag="ACGI3L_003628"
     CDS             2479..3705
                     /gene="pepT"
                     /locus_tag="ACGI3L_003628"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFG9199307.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            3912..4964
                     /locus_tag="ACGI3L_003629"
     CDS             3912..4964
                     /locus_tag="ACGI3L_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HFG9199308.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT         1976 a          505 c          938 g         1614 t
ORIGIN      
        1 tttttctcag catctgaaac ggctttaatg tcgttgagta aaatcagaat cagatatatg
       61 caagatgaag gagttaaagg agctaagtta gtaagttcat taatagaaaa tccaaataag
      121 cttttaagtt ctatattggt tggaaataac gtcgtaaata tagcagcaac atccatatca
      181 acatctttgt ttataggatt aatgggagaa aaaggagtgg cacttgctac agctgttatg
      241 acagtattag tattaatatt tggtgagatt actccaaaaa caatagcagc aaataattca
      301 gaaaaggttt ctctattagt atctaaacct ataaaagcaa ttatatttat attaagacca
      361 atagtatgga tatttaatat aattacaaat attatattta aattatttgg tataacaaat
      421 aaaggagcta aatcattcat aactgaagaa gagctaaaaa ctatggtaaa tgtaagtcat
      481 gaagaaggcg tccttgaaat ggaagagaga gaaatcataa ataatgtttt tgaatttgga
      541 gatatgcaag ctaaaaatgc aatggtacaa agaatagata tggtagctat agatatggaa
      601 gatagttatg atgagataat acaggtattt aaaactgaaa aattaagcag aatgcctgtg
      661 tatgaagaaa ctatagatga tattgtagga atacttaata taaaagatat tatattttta
      721 tctgatgaag aaatagagtc atttgatatt aaaaattata tgagagaacc ttttttcacg
      781 tatgagttca aaaagataac acaacttctt gaagagatga aacttgaaaa aagtcagatg
      841 gctatagttg tagatgagta tggtggaaca tctggacttt taactataga agatttagta
      901 gaagtcattg ttggagatat agaggatgaa tatgatgaag aagaggatga aatacaagtt
      961 ataaaagaag atgagtatat tgtagatgga agtactaaaa ttggtgatgt taatgaactt
     1021 attggtgtaa acttggaatc tgaggagttt gattccatag gaggttttat aattggacac
     1081 ctaagcagat tgccagaaga aaatgaagta attgaggttg ataatataag attttgtata
     1141 gaaagtatag aaaaaaatag aattaaaaaa ataagaatat atacataatg taataatgtt
     1201 cttaaattta ttagaagtgt ataaatataa aagatatctt ttatatttat acacttcttt
     1261 ttattttgta ttcaaataaa actagtatga aatggacaaa ataaaaatat aaattagaag
     1321 aaaggagatt tttaagatga gcatactaga aaataatttt ttatacaaat taaaaaacaa
     1381 cactatcttt ttttgtatat atacattgtt atttattttt atttacaaag cgtttccata
     1441 catagctcca ttttttctag gtgctataat agcacttatg attaatccta tatcacaaaa
     1501 gttagaaaat aagtttcgta taaataaagg tatctctact cttgttctaa gttttcttgc
     1561 agtggctata gtcagtacag ttactacaat aatagtaata aattcaatga aagaattaat
     1621 gggattttta aataatatat ctgctaatcc tgaggatata agtaatacta ttatgtattt
     1681 tttaaataaa ataaatgact ttatgaaatc atttcaagaa atagccaatt ttgatgtaga
     1741 acaattagta aacaaattca gtggtgaagt aatgcaaatt acaaaaaatc ttcttactag
     1801 tatacttgga ttggctactt ctattccata tattataata tttataatta ccttgtttat
     1861 tgctacgtac tttatagcaa aagaccttga taagattgaa aatagttttt ataatatgtt
     1921 tactgttgat gttagaaaga aggtaaaaaa cgtaaagaaa gaggcagggc tttcacttgt
     1981 tggatatata agggcctata caatacttat ggctataaca ttttttgcaa tctggggaag
     2041 ttttgcttta tttggattga aatacggtct aatagtaggg tttgtaggag ctttaatgga
     2101 tttaattcca ttcctaggta taataacaat atatcttcca gtaattgttt attatttcct
     2161 tataaaaaat tattttatag ctataagtat gactgtgata ttttttgttt tgtctttgat
     2221 tagagaaata cttgaaccta aactagtatc agtaaatgtt ggactaaatc cattagctac
     2281 cctagcagcg atttttattg gaatccaagt aaaaggaata attggagtaa ttttttgttt
     2341 gggtttggta tgtatgcatg atatacttaa gaaggtggat attttttaat tataataatt
     2401 gatagatttt ttaaaaataa aattttattc acaggtaaat aaaaaaatat taatcttatt
     2461 aagaaagagg gtatatacgt gaaacaaaaa gtagtggaaa gatttttaaa atatgtatca
     2521 tttgatacaa catctaattc tcagtgtgag aactgtccat cttcagaagg tcaaagagtt
     2581 ttagctaagt atatagttga agagctaaaa acaatgggtg ttgatgatgt gagtttagat
     2641 gaaaatagtt atataatggc tactttaaaa ggaaatactg atggtgtgga tactatagga
     2701 ttcatatcac atttagatac aattgaagat gttagtggaa aagatattaa accaagaata
     2761 atagaaaatt atgatggaaa agacatagtt ttaaatgaag cgttaaatgt tattacgtat
     2821 gtaaaggatt ctccagagtt ggaagaattt aaaggtgacg atttaatagt cactgatgga
     2881 acaactctac ttgggtctga tgataaagct ggtatagctg agatagtgac tgcaatagag
     2941 tatctaataa atcatccaga aattaagcat ggagatataa aaataggatt tacaccagat
     3001 gaagaaattg gtagaggtgc tgatttattt gatgttgaaa aatttggagc aaaatatgca
     3061 tatactttag atggaggaat agttggagaa cttgaatgtg aaaattttaa tgctgcaaat
     3121 gcaaccatta ctatacatgg tagaaatgtt catccaggtt cagctaaaaa taaaatggta
     3181 aatgctatac atatagctgc tgaaatatca gaaatgttcc cagcagatga aagaccagaa
     3241 acaacagaag gatatgaagg attttggcat ttaaattcta taggtggaaa tgtcgagaat
     3301 gtaagtatgg cttatattat tagagaccat tgtaaagaaa aatttgaaaa tagaaaatct
     3361 attatgatag agaatataga aaaaataaat aagaaatacg ataatagagt ggaattggat
     3421 ttaaaagact cttattacaa tatgaaagaa aagattgagc cagttatgtt tatagttgat
     3481 atagctaaag aagctatgga ggaattaggt ataaaaccac gtttagttcc tgtaagaggt
     3541 ggtactgatg gagcaagatt atcttttaat ggattacctt gtccaaatat atttactggt
     3601 ggattaaact tccatgggaa aaatgagtgt ataccagtta gttctatgga gaaagctact
     3661 aaactaattg taagaatagc tgaaaaatat gctgaaagag tttagttaaa aagtatttaa
     3721 aaattaagca tttaaagtta taatagctat atcattcttt ataagtcaag ctgattataa
     3781 gcttgtgttg tacttaaaat ggtatagcta tttttgtaat tatttttata aaagataatt
     3841 atttttagtt tagggtatca ataaaaagta tgaatatcaa taggtattaa catttaaaag
     3901 ggggaattgt attgaaaatt aaatctaaaa aaataatagc atttgcactt tcacttggga
     3961 ttatgttgcc aagttgtgta tatgcagaca ctattagtaa aaatcaaaat gcacaggtag
     4021 atatgaacaa ttatcttcaa ggtagaaaat ctccaaagga ggaaaaactt attggtgaag
     4081 atagatttga tacagcgata aaaatatctc aaagtggttg gaataatggt tcagaaaggg
     4141 tgtttctagt taactcaaat tcattgccag atgcattggc ttcaactcct ttggcaagta
     4201 aattggatgc accaatactg cttacaaata aaaatagtat accatataat gtaacagagg
     4261 aaataaaaag gcttaatcca gcagaagtta ttttaattgg aagtgaagga gctatttcat
     4321 caagtgtaaa agaatctctt gaagatatgg aagtattagt cagtagaatc ggtggagcag
     4381 atagagaaga aacatcttta cttcttacta gacagctaga tgatactggt gatttaggtg
     4441 tctcaaaagt ggcagtggtt aatgggtata atggactggc agatgcaact tcaatatcaa
     4501 gcccagctgc aagtgataat acagctataa tatatacagg taaggatagc ataagaagtg
     4561 aggcaaagaa ttttattaca caaaactcaa ctaagacata catagtaggt ggggagtaca
     4621 gtataagtaa aaaacttgaa ggacagttag taaactcaga aagactagca gggacagata
     4681 gaaaagatac taatgcgaaa gttttagaaa agttttatgg aaaatcaagt aaggttaata
     4741 atatgtattt tgcaaaagat ggaagtggta gagaagctga tttagttgat gggcttgctg
     4801 ctggagtatt agcatcaaaa acaaagtcac ctgtagtact tgcaagtgga agtttaagta
     4861 gtgcacagaa aagttttata aaaaaagtaa aggctgataa atttgtacaa gttggtggag
     4921 gtaaaaatag taaaccatat gcagaagcat tagccttaca gtaatattgt gtaaatcaaa
     4981 attaatatat aataatagca agtaaaccaa gttgcacttc aatatatata ata
//
LOCUS       DAYAKB010000148         4982 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.151, whole genome shotgun sequence.
ACCESSION   DAYAKB010000148 DAYAKB010000000
VERSION     DAYAKB010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.151"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            341..1513
                     /locus_tag="ACGI3L_003630"
     CDS             341..1513
                     /locus_tag="ACGI3L_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9199309.1"
                     /translation="MIIWLSDPINILFTLFGYFILLIICSKSKLIPIISVVMILYPII
                     IGLNFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQY
                     LSNKIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAIL
                     ANIGVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIES
                     YLEIEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNID
                     IDNHLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKV
                     NPINRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
     gene            complement(1849..2418)
                     /locus_tag="ACGI3L_003631"
     CDS             complement(1849..2418)
                     /locus_tag="ACGI3L_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HFG9199310.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVEGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            2821..3393
                     /locus_tag="ACGI3L_003632"
     CDS             2821..3393
                     /locus_tag="ACGI3L_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HFG9199311.1"
                     /translation="MEYIINPCSGIKIKITRGQKIEIVDIEGGQVVDFFAEMKDDSTE
                     FISPGVTIDCNESLRLQVGNLIYSNKYRPMFKILYDDVREHDLLHPCCRPEMYDFFYH
                     NGENHPNCFDNINRTLGTSHQIIHPINLFMYTKVNTDGSIEVCEPLSKANDKIILEAL
                     ENMTLGIAACSVSESSCNSRKCTSIKILVD"
     gene            complement(4072..>4982)
                     /locus_tag="ACGI3L_003633"
     CDS             complement(4072..>4982)
                     /locus_tag="ACGI3L_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFG9199312.1"
                     /translation="GNVLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIG
                     TFGKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHKYIFGMVVLIFVIRFIFSAVSF
                     GSGAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPL
                     TGIILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKER
                     GEKILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVT
                     MTDERDSGAVYDKMENLCKEHTAHIF"
BASE COUNT         1804 a          816 c          577 g         1785 t
ORIGIN      
        1 aaacttaatt tttaaaattt caatctttta aaactcaatt ttttgaagct taatttctag
       61 aattttattt ttcaaaatca attctttgaa atctaatttc cagaatttta atttttaaga
      121 tttaattttt taaaacttag tttccagaat cttaattaat agaaaggtat attaaatggg
      181 cacttattct ttaatctcta caagcataaa ttttattcta atattaatca atattttcat
      241 agcctttttt ctttataagt tgacttccta ttttatagac tttaggaatc attggatttt
      301 caaaatcata ttgattttgg gctactctat tattagtcaa atgataatat ggctttccga
      361 ccccataaat attttgttta cactattcgg atattttata ctacttataa tatgtagcaa
      421 aagcaaatta attcctataa tatcagttgt catgatactt tatcctatta taattgggct
      481 taattttctt tttataaaca accctatata tgaggaactt atacactcaa aagagtatat
      541 tttaatactt tcaatagtcc agataatttc tgctctaatt aaattattat tttggttttt
      601 aatacatatt ttcctaaaga atagattggt caatataaaa caatacttat caaataaaat
      661 atggattttt attgatatgg tatgtatatc ttcattttta tcaatattaa ttgctattat
      721 tctgccacct actaatttaa tccctatggg tagtaataag aatattatct taggcaactt
      781 accttatggc acttatctaa tcatcttgtc agcaattctg gcaaatatcg gtgtgatact
      841 tcttttacag ccattgattg aaaatgtaaa gatgaagata gaaaaacaag caaatcacct
      901 aaaagaaaaa tactataact tactagaaaa tcaacaaatt caaatacgca aaatgcgaca
      961 tgatatgaat aatcactttc aaatgattga atcgtattta gaaattgaag atattgctgg
     1021 agctaaaaag tattttaatc agttaaaaat aggtataggt actcttagtg gaaaacaatt
     1081 ttgcaaaaac caagctctta actcaatttt aaatcttcgt catacaagtt tagaagaaaa
     1141 tggtgttgat gtgcacttta atatagatat agacaatcac ttgggtatag aacctataga
     1201 tttatgtact attttttcaa attctttaga taacgctata gaagcatctt tgaaaattcc
     1261 tgatttgtca aatagaaaag tggtattaaa ggcacgttgt gagaaggagt attttagcta
     1321 tttattgaca aacaacaagg taaatcctat caatagaaaa caagaactat ttatttcaga
     1381 taaaaaagat agtaattctc acggatatgg tattgagaat attagagaaa ttgttaataa
     1441 gtacaatgga aaattggata tttcttatac tgagagtgaa ttttctttat ttctttatat
     1501 tagattattt tagtctaaaa ttagattatc ttatataata caaattagat tgtttgatac
     1561 tatgtaaaat tataataact tataattaaa tatttacaca tatattcatt aacttaaaat
     1621 ttaatcaaat gtgatatttt atttacctta gtaaaaatgt gtgtgtctca aaataaactt
     1681 tttagttgat gaggcactct tttttacatg aaatcaaata tatttttatc ctttcaacaa
     1741 tgaaaaatgg atttatctct ccattttgaa acaagccctt tttctattaa ttactttctt
     1801 aaaaaatata atacgatata taagataaat atctaattgt acctatttct aattatatct
     1861 attagaatac aacacctttg ccttttcagt aaactcccta acaaaatcta gtttactatc
     1921 tgtataagca tcacgattat gctcatactt cttccaaagg tccaacttaa gtttttcata
     1981 ctcctttgca acatctgggt ggtcaattaa gtaatctcta aaaaacaact catcattatc
     2041 acctacatac cttatatgca aatgaaaaac tcgttcttca aacccctcta ctgtataccc
     2101 tttattaagt gaaagcctac tactgctctc agacatacaa atatatccat tcgactcaat
     2161 caaatcttta atatctttca tattataatc aggaattatc tcaatcagta tgtcaacaat
     2221 gggcttggca taaatcgtac tcacagaagt acttccaata tgacttattc taacaatttt
     2281 ttgcattggc aatattccag ttagtctata ttgttcttct ttaaaccaat ttttccaaca
     2341 ttctttgtga gtagtcaaaa atataggaaa caagttccat aactcctcta aagtcatatc
     2401 ttccaacttc tttttcatta gttacctcct tttaaatttg tactttatat tttttctttt
     2461 tcaaatttac ttagttaata tttaacttta ttttttatca aatcattttt ctaattatgt
     2521 aaatttttct aaatttagtt tttaatgtat tataacagat ttttaccctt cttacacttt
     2581 tgtatctatt taaatattag aacatttttt cttacttcta aatacagtaa gattgcttaa
     2641 ataccaaata ggagcaaaaa aactctgtaa tctaaaaaaa actacaacat ctttatgaga
     2701 attaaaaaat gatagactat gttatcaaca ttaagaaaca gatagaaaag aaacagagta
     2761 tgtgctaaaa tgggaacata gaacagaatg acaaattgga atttatggag gacattaaat
     2821 atggagtata taatcaatcc ttgtagtggt ataaaaatta aaataactag agggcagaaa
     2881 attgaaattg tggatattga aggaggacag gtcgttgatt tttttgcaga aatgaaagat
     2941 gattcaactg aatttatatc tccaggtgtt acaattgatt gtaatgagtc attaagatta
     3001 caagttggga atttaatata ttctaataag tatagaccta tgtttaaaat tttatatgat
     3061 gatgtaaggg aacatgactt gctacatcca tgttgtagac ctgagatgta cgatttcttt
     3121 tatcacaatg gagaaaatca tccaaactgt tttgataata ttaatcgcac acttggaact
     3181 tcccatcaaa ttattcaccc cattaatttg tttatgtaca caaaagtcaa tacagatggg
     3241 agtattgaag tatgtgaacc tttatcaaaa gccaatgaca aaattattct tgaagcattg
     3301 gaaaacatga ctttagggat tgctgcatgc agtgtttcag aaagttcttg taatagcaga
     3361 aaatgtactt ctattaagat tttggttgat tgacaaattt catttatcga aaaaatatca
     3421 aaattaaaaa atgacgtcaa aggcgcaaaa gggtaaccac ttgcgctctc aattcattat
     3481 ggtttgttac gtatttatgg gtaaaaatcc cttgattcta tgatgttttt cagacacaat
     3541 tacaaatgag taaggatttt atactcatac tctaaaaaat agcattttat tgcgtaacag
     3601 aacgaaaaaa cagtgtgtac ctttttcttg caatacacac tgtattcata gccactctag
     3661 ctgttaactg ttaattatct cataataccc ttactggtat tcatctaatc ttaacccctt
     3721 ttaattattt tcatttataa ataaattcta ttcttcccaa aatatcgtaa ttaaaatata
     3781 ttaattaaaa tatcccaata agaatatctg aaaaatcttc tacctatttt ttcaaacctt
     3841 ttattcccat tcctcataca atagtgcaac ttttagcaca gtataaatat accattagtc
     3901 catataatct cattaacaaa tatatacaat tattttcttc aaactctttt atatctaaga
     3961 tatcacattt tcattttctt atattaattc cttaactctc tttcaaatta ccaatttttt
     4021 aatcaaatct tcattaaata ttctatcatt attaaacatt catcattatc cctaaaaaat
     4081 atgtgccgta tgttctttac acaaattttc catcttatca tacacagcac cactatctct
     4141 ctcatctgtc atagtcacaa ttacatcact tggtctaaga attgtcttac ctctaggaat
     4201 aatttcttct ccacctcttt gaattgctac caaaagacaa ttttcaggcc actgtacatc
     4261 ctgaattgcc ttgttcgcaa caggagagcc aaacataaca gagaactggt ctagtatctt
     4321 ttcgcccctc tctttatgta caggttctcc attcttttca agtaacctct caagaagact
     4381 ttcataaata ggtttagact tcataagtgt agccacaata tatgccacaa ttgaaattac
     4441 tgatagtgaa agcatttgac taacagaacc tgtcatttca aaaattaata tgataccagt
     4501 caaaggggca cgcacaatag ctgtaaaata tcctgccata gccaaaagca caaagttatt
     4561 tacataatcg ggattcattc caaaaacttt aacacctacc ataccaaata ttccacctat
     4621 aaatgctcct aaaacaagca atggaaaaaa tattccccct ggtgcacctg acccaaaact
     4681 aacagccgaa aatataaaac gtataacaaa aatcaaaaca accattccaa aaatatattt
     4741 atgacttgta agttcttcaa ctaaattgtg tccactcccc agaacatcag gcataacaag
     4801 cccaagaata ccagccatta taaatggaat caacagtttt ccaaacgtac caattttagg
     4861 aatcttcttg tataaagact gcacatatag agtaaaccag ttgtaaaatg cccccataac
     4921 tccaagaata acacctaaaa tcactattaa tccataataa tcttgtggca acacatttcc
     4981 aa
//
LOCUS       DAYAKB010000149         4913 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.152, whole genome shotgun sequence.
ACCESSION   DAYAKB010000149 DAYAKB010000000
VERSION     DAYAKB010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4913
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.152"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(221..2356)
                     /gene="rnr"
                     /locus_tag="ACGI3L_003634"
     CDS             complement(221..2356)
                     /gene="rnr"
                     /locus_tag="ACGI3L_003634"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFG9199313.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            2949..3563
                     /locus_tag="ACGI3L_003635"
     CDS             2949..3563
                     /locus_tag="ACGI3L_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HFG9199314.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3581..3943
                     /locus_tag="ACGI3L_003636"
     CDS             3581..3943
                     /locus_tag="ACGI3L_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9199315.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4049..4546
                     /locus_tag="ACGI3L_003637"
     CDS             4049..4546
                     /locus_tag="ACGI3L_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HFG9199316.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1635 a          735 c          603 g         1940 t
ORIGIN      
        1 tttcagttag ctctttctat taaacatttc tcaattactt atttttcaat tagctacttt
       61 cattaaatat ttcttaatta tttatctttc agttaactat ttccattaga tatttctcaa
      121 ttacctattt ttatcattta ttttatagag tattgtgcac tatatattta tacatatcat
      181 aaatactaca acttgttatc tcttatttta gctgttttat ctactcctct attttttcaa
      241 ctatctcaaa gtcaatttct ttaaaatcta cattaacact ttcaaccttt atcttaacaa
      301 ggtctcctat cttatatgac ttcttagttc tttctcctaa aacactataa gaactctcat
      361 cataaatata gtaatcatca ttcatatttg caagtcttat caatccttct atggtattat
      421 ccaactcaac aaatattcca aatgaagtta cgctagatac aacaccctca aattcttgac
      481 caactttatc cttcatataa agagccttat agaaatcatg tacatctctt tcagctaact
      541 ctgcctttct ttctttctcg gatgattgaa cagatgcata atccactata gtagtaagct
      601 gttcttgtct ttttccactt attttattat ttaaagattc ttttattatt ctatgaattt
      661 gaaggtcagg atatcttctt attggtgaag taaagtgaca gtagaattta gctgctaatc
      721 caaaatgtcc actacattct ggtgagtact tagcttgttt taaagaacga agcattatag
      781 tactgatagc tccttcttct tttttgccct ttattttctc tattatacct tgtaatgctt
      841 ttggatgtac ttcctcttta tcacctttta ttatatatcc aaatgtagat ataaacttac
      901 tcaattcttc cattttttcc aaagatggtg tctcatgtat tctatacaca aacggtattc
      961 ccatccagta aaaatgttcg gcaattgtct cattacttat aagcataaat tcttctatta
     1021 tcttattaga tattcttctt tcatatggct ttatatctac aacttcgcct tttccattta
     1081 gaattatctt tgcctctggg aaattgaagt ctatagctcc tcttttttcc cttcttgaca
     1141 taagaatcct agctaaaatt tcagcatttt taaaatcttc aacaacatgt tcaaaagtct
     1201 ttttaagttt ttcatcatcc ttttctaata tatcagatac ttctgtataa gtcattctag
     1261 cttttgaatt tattacagat tcacatattt catgtttaac cacatttcct ttatggtcta
     1321 tttccataaa tatagaaaga gttaatttat cttcaaatgg atttaagcta catactccat
     1381 ttgaaagagt ttttggcaac attggaatta ctttatctac taaataaact gatgtagctc
     1441 tttttaaggc ttccttgtca agtttatttt tctctcttac ataatgtgta acatcagcta
     1501 tgtgaactcc tagtttgaag tttccattag gtaatacttc tattgatatg gcatcatcta
     1561 agtcttttgc gtcatctcca tctatagtaa atatgtttaa atctcttaaa tctcttcttc
     1621 tttttatctc ttcttgagga atctcaacag ctacagcttc tgcttcttgc aatactttct
     1681 ttggaaattc ttctggaaga ccatgttctc ttattataga atctatttct acgcctcttt
     1741 cacctttttg acctagtatc tctataattt tgccttctgg ttttctatcc tcttgtggcc
     1801 atactgtaat ttcacatact accttatcat tatctactgc tccactaaaa tgttttttag
     1861 gtatatatat atctttagta aatttcttgt tgtctggtgt tacaaatcca aaagttttac
     1921 ttgattggaa agtacctact attctagtta tttctctctt tattactttt actattcttc
     1981 cttctgctct cttttcttca gttgcaggta ctactatttc tgccataact ctatcattat
     2041 gcatagcacc atttatattg tcacttgaga taaataaatc ctgtgtatat tcaacatcag
     2101 attctacaaa tccaaaaccc tttttgtgtg atacaaattt tccaacaaag tatcccattt
     2161 gattgggaga tactattttt ccttttttag taaagcagat ataaccatct tcttctaatt
     2221 catttaaaaa attataaaac attggcattt ctgatgaatg tatatcaaat atttctgcta
     2281 attcttcttt ttttagagga ttatatgcac tttcatttat taatcctagc aaactttctt
     2341 taagtcctgg tatcattttt ccctcctgtt ttacttttca ttatattatt atttatattg
     2401 tcttttatat ttcttcagac aaaacatttt ttaattatca cataattttc tatattttct
     2461 tattattata agttaaaatt acttatttat atttttgatt taatgtaagc tttgtcatac
     2521 taacttcaaa caaattatga tgttttataa attatttgta aatatcatta taattactta
     2581 agttattctt tatcataatt gcttaaatta ctctttatca cctaattata caccatcaaa
     2641 taggattggt aaaatattca tctcatataa gtattactat ataataattt attctattag
     2701 tatactcaaa tcatgtaaaa tttatataac tcaattaatt ttttaaatac aactttataa
     2761 tataaaactt ataataaaag taaatttata tgttaaatga ggttgatttt ttattatttt
     2821 ttatttatgc tagtactaaa gacttgcaaa cgttttttga caagtcttta ttttgtctaa
     2881 attaaacaaa cttttttaca aataaataca taaaatttaa actaatctat ttattggagg
     2941 agataaaatt ggaagaagta attgcaaaaa ttattactat agaaaatgga ttcaaagaaa
     3001 ttgaaaacat tgctaaaaaa attgtaaaaa ataatgactc aaaaaagtgt tattatctat
     3061 caatctactt atataggtca gaatattatc aagtaagaga attggctgtg tttatacttg
     3121 gttttatatc agtaactatt tctgaagctt tgttattttt aaaagataat gtgagtaaag
     3181 atgaaaactg gagagtacaa gaaatactag ctaaatcatt tgattattat tgcagtgaag
     3241 taggatatga aaaggctctt cctgttataa aagaatggct taattctgat agtccaaaca
     3301 taaaaagggc tgtgacagaa ggtcttcgaa tttggactag tagagactat tttaaatcta
     3361 atcctgacgt tgctatatca ctactttcta gtttaaaaga agatgatagt gaatacttga
     3421 gaaagtctgt aggtaatgct cttagagata taagtaaaaa atatccagat ttagtaaaaa
     3481 aagaattaga ttcatgggat atatcaaata aaaaagttga gtttgtatat aagcttgctt
     3541 caaaatgtat cttggcaaag taaaatggag gtgaacttat ttgaaacttc gtgatgagta
     3601 tacttgccca ttagaactaa cacatgatat gataaaaggc aaatggaaat ctattatatt
     3661 atggagatta cgcataggac caacttcctt atcaaaactt gaaaaggaaa tcaatggtat
     3721 taatcaaaag atgttacttg aacaacttaa agaattaatt gaatttggtc ttgtagataa
     3781 aaagacatat gaaggttacc cacttaaagt tgaatactca cttacaccta ttcgagggaa
     3841 acaaatattg gatgctttgg ctataatgca agatatagga attagcttta tgttggataa
     3901 tggtatggaa gatattctta aggaaaaagg tgttttaaaa taaatagata cccacaaaaa
     3961 agtaagtaat ttaccattat tttcaactgg tatataatta aattatagat atattctatt
     4021 aatttattat aataggaggt aaattattat gaaagtaact agtacaggta tagtaaatgg
     4081 tgttatagaa gataaatacg gtaaaagagg aactcagttc aatgaaggtg gtatgcctac
     4141 atattcacta cctctaaagt ttgaagatgc tccaaagaat acagtatcct ttgctgtatt
     4201 tttagaagat aaagactctg ttcctgtatg tgggtttgca tggatacatt ggttagctgt
     4261 aaatataaca aaagatgagt taaatgaaaa tgaaagtgta acagctactg attttgtaca
     4321 agggactact agttggcatg gcaaactagg aggtcttgac agattagagg ccagtgtata
     4381 tggtggaatg gctcctccag acagacctca tgtctatgaa atacatgtat ttgcacttga
     4441 tactatcctt gaccttgaaa aaggattcta tatgaatgaa tttttcaaag ctattgaagg
     4501 gcatgtttta gatacattta cactaaaagg aagttattct aattaattag gttgactata
     4561 gctaatcatt aattaaatgc tacatttaat tgatgattag cttaattgtt attagaatat
     4621 tttctgcact ttatcttaat atatatttta gttgactggt attttaattt ctattagatt
     4681 attatcaatt tatataaatt gattttagct taaaacttac ttatctattt cagtttctat
     4741 tagaattatt attagactca ttaaaataaa agcactaata taactaataa tatatgttaa
     4801 attcattaac tctacataaa gttttataat ctaaatgaaa tacaataatc tgcataaaat
     4861 tcaatagctt atataaaatt taataattta tataaacatt atcaatctat ata
//
LOCUS       DAYAKB010000150         4667 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.154, whole genome shotgun sequence.
ACCESSION   DAYAKB010000150 DAYAKB010000000
VERSION     DAYAKB010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4667
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.154"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(48..194)
                     /locus_tag="ACGI3L_003638"
     CDS             complement(48..194)
                     /locus_tag="ACGI3L_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199317.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(333..1259)
                     /locus_tag="ACGI3L_003639"
     CDS             complement(333..1259)
                     /locus_tag="ACGI3L_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFG9199318.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            1449..3320
                     /locus_tag="ACGI3L_003640"
     CDS             1449..3320
                     /locus_tag="ACGI3L_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9199319.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(3412..4347)
                     /locus_tag="ACGI3L_003641"
     CDS             complement(3412..4347)
                     /locus_tag="ACGI3L_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFG9199320.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
BASE COUNT         1842 a          528 c          714 g         1583 t
ORIGIN      
        1 aatctatttt acttctctat tgtgttaaaa aacttatttt taaatgttta caaaaacatt
       61 ctatatacaa ataaaattat tagcaatatc aacgctattt taaaagctaa actagcaaca
      121 gttttaatga tttttacaga aacacctata gcaactatag caaatactat tttaaagagt
      181 aaatccatat ccatatttaa gcctcctatt ctataataca tatagatatt attgacaaat
      241 atctaggaaa aaattccatc aatatactac aataaaatgt ttatatttgt aatttattga
      301 atatgttatt atataataca taaaaaaata aatcaagata agagtaaaat acttataaaa
      361 ggtatagata taactgaaaa tagtgttgta aaaaacacac attgtgaagc tagtgttata
      421 ttggagtcat attgattagc cattatagca gtatttgcag cagcaggcat tgaagaaatt
      481 actactggta tagctaaaat catcttatca tttatccatc cttttagaat aaaatacaca
      541 atcacaggaa gtaccaataa tcttataaaa gtgactatat ataatttttt gttgacaaaa
      601 caatcgagag ctgaagaatt agcaagtaag cttccaatga taatcatgga tattggtgta
      661 gttatacttc ccaacatctc aagtggctcg tttataaatt ggggtaacct aagtcctgtt
      721 acaaataaaa aaagtccaat aacaatagct attgtagcag ggcttataag tgattttatt
      781 gaaaaacctc tacttgtact gcctttagat aaaagataaa ttcctaaagt gaaagaaaat
      841 aagttaaaag gcaaattgaa tattgcagta tagaatattg cttcatgacc taaaactgct
      901 tcaattacag gataacccat aaaagcaaca tttgaaaaaa caactatata ctggtatatt
      961 cccaaatctt ttttatcatt acattttaaa atgtatttca ataaaaatgc aattataatt
     1021 gaaactatat acataatcaa agatgtaaat aataacaata gtattttttg tatcatttta
     1081 ctatcaaagt taatttgcat ggagctaatt atcattgatg gtaaaaaaac tgtcattgtc
     1141 aaagttgaaa gcttagatgt gcagtggtca tctaataagt tgaattttct gacaaaatat
     1201 ccaactaaaa taattataaa taaaactgca acttggataa aaatattgct gaaattcata
     1261 aaatgtcccc cctatatata cattatatac caattacata ataaaatcta atgattataa
     1321 aatttaaaat ttaatgttac aatatagtga caaaaggtaa aaattcaata ttatagcatt
     1381 aattgtagat tataatgtat aataatgttt gagagaatat attttataaa atgggtaggt
     1441 agcgaataat gaaaaataca aaattttcta taaaaaaaat aaaaaatata tctaatgacc
     1501 cgaaagtcgt acatactaag ggtgccctcc ttgaaaagat gggtaagatg gaaagcgcaa
     1561 tagagttgta taagagtgct gcattggata attacgtaaa atctcaatat actttaggaa
     1621 atatatatga aagtaaaaaa caatttaaag aagcagaaaa gtggtattcg atggcatata
     1681 aaagtggaag tgaagatgct gcttttgatt taggtaatat gtactataag ttagatggct
     1741 atgaatatgc tatatattgg tatgaaaaga tagcaaattt aggttattta caagcacaaa
     1801 ataatttagg tgtatgccat tttaaaatga aagattttgt aaggtgtgaa aaatggttaa
     1861 aaacagcagc agacaagaat ttaggtaaag cttgttttaa tttaggggta ttatatactt
     1921 ttttggagaa agatgatgaa gcatatgaat actataaaaa aggttctgtg cttttagatg
     1981 atgatgcaaa atataattta gcaatattaa atggaaaaaa gaaagataat aaatcaacag
     2041 taagtttata taaacagttg tacaagtcag gtcatatgaa aggttgcttt aacttgggta
     2101 tgattatgga aataaatgat aatttagaag atgcagagaa gtattataaa aagagtgctg
     2161 atagagatga tgtgaagtct gagtataggc ttgcatatgt atatgataga aaagaagagc
     2221 tgggagatgc aatttattat tatgagaaag caatagaaaa aaatcataca ctttctaagt
     2281 atagacttgc taatttatat aatagagaaa atgagataga gaaggcaaaa acttattata
     2341 aaatggctgc tgaagatgat ataacagaag caaaaaataa tctggcaggt atatattttg
     2401 aagaaaaaga ttatgaaaat gctattaaat attatgagga tgctatagct gttggatgca
     2461 aaagttccct tgaaaatcta ggggatttat attatcagaa tcaagatata gaaaaagcga
     2521 tttcgtatta ttcgaggatt ccaaataatg tatcttgtca aatcaaatta ggaaatatct
     2581 atgaagattt aaataatatt gaagaagcaa taagttggta taagaaagca tctgaaaatg
     2641 gagatacgag gtctagttat agattggggt gtatatatga gagcttagga aatacaaaaa
     2701 atgctagaaa gtattttgaa atggcaagta gcaaaaacca tatgaatgct cgtatacatc
     2761 taggtagaat ttattttaga gaaggtaaat tggaagagtc taaaatgatg tttgatacac
     2821 ctgccaatga aaataatgtg tatgctcaac atatggtagg attaatttat gatatgttct
     2881 ataaagatta tgtaaattct aaattttggt atgaaaaggc tagagcacaa ggttgtgttg
     2941 aatcaatata taatttaggt caaatttatt taaaattaaa tgatgacgca gaagctgaga
     3001 aatattataa agaaggtatt aaatatggaa gtaagaagtg tgagtatatg cttgcaggtc
     3061 tttattataa aaagagccta gatatgtaca tttctttagc aaatgaagag tacgataatt
     3121 gtgaagagat agtagaaggc tttccaaatt taaatataga ctttgatgaa gtattaattc
     3181 ctccatttaa gttgcaagaa gaggtaatag atgaagaaga gtatgtacca atttatatac
     3241 taaatataaa agaaagttta gattcaatgc tagaagggct tgaaactgaa atgattatag
     3301 atgaagaaca tgatagttaa aaagtattat aagattatat agatttaaat atataaaagc
     3361 cattaggata aatgtaaatc aattaattct aatggccttt ttattaatat tttataatag
     3421 cttatttctt gacatgaaaa atgtaatcac tatacatatt atagaggtaa taagaagtat
     3481 tatccaaaat ccgtttgggt tattagaaaa tggcatgttg atgacattca taccaaagaa
     3541 tcctgatatt attgtaggta ttgagaaaat tagtgtaact actgttaaaa tttgcataac
     3601 attattctga ttattactta taattgcact gaaagcatcc ataattctac tcaatatatc
     3661 tccatatatt ttagccatat caagagcctg tctattttca actataacat cttctaatag
     3721 gtcttcatca tctggatact tctttatacc agcagttcta accattttgt ttaaaacaag
     3781 ttcattagat tttagtgagg tagagaagta taccaaagat ttttctaatt ccaataattg
     3841 aaccaattct ttgtttttca ttgatttgta aatttctcgc tctattatga ttgtcatttt
     3901 atttattttt cttaagtaat gcaagtaata agctgcattt ttgtgaagaa tttgaagcaa
     3961 aaagcgagtc tttttaaacg taaaaaaatc tttaatatga ccaactataa agtcatttaa
     4021 aatcttagtt tgtgcatcac aaactgttac aatagcttct tcagttagta taatacctaa
     4081 gggtattgta gtataatgag aagaattaga gtcactttcg tctactggta tatctataag
     4141 tataagagta tgattgtctt caacatctat tcttgagcgt tcttcttcat ctagtgcaga
     4201 ttctatgctt tctacatcta tatttaataa attagaaatt tcgttgattt cactatgatt
     4261 aggttcaaca agatttatcc aacagccatc ttcaaaaaaa ctaagtttct ctaattttga
     4321 atctatagtt ttgtaatatc ttatcatggc aacacatcct ttattcagtt ttatataaat
     4381 ctcatcattt aatagtatct attaattaac taatttatat aactgaatat atgtattagt
     4441 tttgatttta gatattatta agtgatgaaa atgtaaaaaa ttctctccgc aacggactag
     4501 tatccattgc ccatcactct ccttatttat tattttatat atagctattt atgaaatgcg
     4561 tattttaagc actctttaat ataatacctt ttccaggtat ataaatcaag ttttgatttg
     4621 attaaataat atttttacca taatttacac ataaagtata taagtta
//
LOCUS       DAYAKB010000151         4605 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.155, whole genome shotgun sequence.
ACCESSION   DAYAKB010000151 DAYAKB010000000
VERSION     DAYAKB010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4605
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.155"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            181..810
                     /locus_tag="ACGI3L_003642"
     CDS             181..810
                     /locus_tag="ACGI3L_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199321.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            811..1593
                     /locus_tag="ACGI3L_003643"
     CDS             811..1593
                     /locus_tag="ACGI3L_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199322.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1586..2464
                     /locus_tag="ACGI3L_003644"
     CDS             1586..2464
                     /locus_tag="ACGI3L_003644"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199323.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2497..3456
                     /locus_tag="ACGI3L_003645"
     CDS             2497..3456
                     /locus_tag="ACGI3L_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9199324.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3771..4463
                     /locus_tag="ACGI3L_003646"
     CDS             3771..4463
                     /locus_tag="ACGI3L_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9199325.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
BASE COUNT         1828 a          415 c          844 g         1518 t
ORIGIN      
        1 agatgtatgc attattaatt aaaataaatt acatatacta tttaatattt catttaaaat
       61 attaaaaaat gtagataaaa attgttttat taagaaaaaa ttaatatatt gacaaaattt
      121 aagtgctcat ttaaactatt aattgataat aatattcaat attaaataat aggaggcgtt
      181 atgaataaat atcttctaat aaatccagtg gcagaaagaa tgtatggaga aaagtttcac
      241 cttattaaag caaatttgat aaaaaagggg tacataatag cagaatgtga accacagtta
      301 gaatatgtaa aaaagcagta caaagagtat acaaaaaaga ctgaaaatac aatgttggat
      361 tgtagatgtc cagaaagtat aagtctttta aaaagaaata atttgataaa tgattttgaa
      421 gtacctatga tagaaccaat attagtaagg acttgtaggg ttttatacga taaatatata
      481 aaaagtaaag atgatatgtt ggtagtaacc tgtccatgta cacaattaag agactttgca
      541 agtgaaaagt ttaaggataa gggtaatgct atgttttata catggaaaga gtttgctgaa
      601 caagaaggtg taaaatcact tggaaaaata gatgaatcac caattccatt aggatatttc
      661 aaagatactt ttgaaaaagt tcttgaagta tcaagtgaag acgaaatatt aagtgaaata
      721 caaaaaataa gaaatggctt tgaagataag tatgacatag tagaaatgtt ttattgtaaa
      781 gatggttgta ataatggaga tggtttgtaa atggtcaata aatttaataa taagttttta
      841 aggctagtaa agagtgtttt gatatttttt ataattcttt tattatggaa aattacaaat
      901 tatcttggta tttggagtga ttatatatta ccatcacctg aaaaggtata tagtacattt
      961 ttaaatatga taagtgatgg ttcaatattt attaatgtat atgcaagtat gaaaagagtt
     1021 ttgataggtt ttgcaataag tactgctata ggtgtgcctt tagggatatt ctttggaatt
     1081 tatagtggag tatacgaata ctttaaatct ctaataaatt ttttaaggaa tacacctccc
     1141 cttgctttaa taccaatgct tatattatgg tttggtatag gagaggaatc aaaaattata
     1201 attatagttt tagcatcctt tttcccaatc tttacaagca cattgaaagg gattaaaaat
     1261 tgtgactcaa aactgattga agtgggtaga gtatttgagt tttcaaagct tcagataata
     1321 tttaaaataa taataccaaa tgccattctt gatattgctg ttgggttaaa gttagctctt
     1381 ggatatagct ttagagccat tattggggca gaacttgtag cagcttcatc tggtcttgga
     1441 tacttgatat ctgatggaaa agaaatgtct agaacagatg ttgttattgt aggtataatc
     1501 gtaattggac ttttaggaat aattacagat tacatatttt cgattattgt gaagaaggta
     1561 agtaagggaa agatggtgga agcatatgaa taatttagta tgtgactctg gatatataat
     1621 tagaaattta tataaaagtt ataaagttga caatgaagaa catgtagttc ttagtgatat
     1681 ctctttaaac atagatagaa accatataac agtaatttta ggtgaaagtg gttgtggaaa
     1741 gactaccttg cttagagcaa ttgcatcact tgaaggtata aatagtggtg aaattaggtt
     1801 tattaatgat aataaagagt atagacctaa tgttggtttt gtttttcagg agagcagatt
     1861 aatgccttgg ttaaacgtaa gtgaaaatat agcttttcat aatcaaagaa aaaatactat
     1921 tttaaacaag gtgcttagaa aatttaaaca caataaaaga attagcagta aaattataaa
     1981 tgataatttt agaagcttag aaacaaatga taatttgaac aaatcaaata aatataatag
     2041 gaaaagtaat attgatgtag aaaaatatct taagatgatg aacttgcaga aatttaaaaa
     2101 ctcttatcca aatgaattgt caggaggtat ggcgcagaga gtaagcatag ctagagctct
     2161 ttctttcaat ccagatatgt tgcttatgga cgagcctttt tcggcattag attattttac
     2221 aaggattgat atgcaaaatg aagttataag aatacataag tcaactaata aaggcgtgat
     2281 atttgtaact catgatattg atgaagcgtt aaagataggc aagaaaatag ttgttttcac
     2341 agacgaaaga aaagtaaaag aatttaatat agaagatggt tataatagag atttaacttc
     2401 agattactat attaaattaa aaaaagatat tttaatgaca atgaaatcaa ataaaggcat
     2461 ttaaagaaat taataatatt ttaaggagta aagtaaatga aattaaaaaa gctattgata
     2521 ggtataacaa tattaacact tgcaacagca tctttagctg gatgtgctaa aaaaaataat
     2581 ggagaaaaac tttcagaaat aaatttaact tatgtaaaat caccattaaa tgttccttct
     2641 ataattcaaa aacaggatga tttatttgga aaggaattta aaaaggataa tataaaagtt
     2701 aatttccacg aaattactac aggtccagag caaacacaag ctttagctgc tggagaaata
     2761 gacttcttac atgcactagg tggtacatca gctttaatag ctgcatctaa tggagtagag
     2821 ttaaagatat taaacactta tagcaggtca ccaaaaggat ttatgatttt gactaataat
     2881 aattcaataa aatcagcagc agatttagta ggtaagaagg tggcaggccc aaaagggact
     2941 atattacatc aggtattgat ttcagcactt gataaagaag gattaagtat ggatgatgtg
     3001 gaatttgtta atatgggtat tccagaggca tcagcagctc tttctgatgg cagcgtagat
     3061 gctgcattga ttgctggtcc agcagctctt aaagctatga agtcaggtag taaacttgta
     3121 gcaaatggtg aaggtttagt agatggtata atagtaactg ctgttagcac agactttgca
     3181 gagaaacatc cagaaatagt tgaaagattt atgaaggttg aaaaggaaac tttagaatat
     3241 gtaaataata attttgatga agctatggaa aaagtagcta aagaagttga tttaagtctt
     3301 gaagaaacta aagaattata tgcttggtat gattttagtt tagatataac agataaagac
     3361 atatcttcgc ttgaagatac acaagacttc ttaataaaaa ataagttaca agagaaaaaa
     3421 gtgaacataa aagaattaat ctataatgct aagtagaaac tatgataaaa taatactaag
     3481 taagaaatat agtaaaagtt taagttacct tattaaggta actttttcta ttttgaatta
     3541 gtaatttcaa tttattttag aatgattagt tgataataat gattaattaa tcataaaaag
     3601 atactttttt atagagtttt attaagatgt ctaataatat ggttatactt atgaagtcag
     3661 taattgtgaa gttagtaata tgattaaatt tatatattgt aaaaagatta taatatatta
     3721 aaattggact gttaatatga tgagtaaata ggtatattag gaggaattat atgagttata
     3781 aagtatatat tgtggaagat gatatatcaa taagtacatt acttaaagat tatattgaga
     3841 aatatggatt tgaagtgatt gttgaagaaa actttgatga tataatgatt acatttgaaa
     3901 gttttaagcc acacttagtt ctattagatg taaatttacc taaatttgat ggtttctact
     3961 ggtgtagatg tattagacaa cagtcgaatt tacctataat ttttatatca gctagagatg
     4021 gtaatgtaga ccaaattaga gctttagaaa gtggagcaga tgattatata acaaaacctt
     4081 tttactatga tgtagtaatg gcaaaaataa agagtcatat aagaagggta tatggtgaat
     4141 attcacctaa aatagacgaa agaatagtgg agctagatgg attaaagttt tatccagaga
     4201 ggttagaact agaattaaat ggtgagaatc taattataac taaaaaagaa ggtatactga
     4261 ttgaatgtct tatcaagaga tacccaaaag tagtaagtag agattatctt ttagaaaaga
     4321 tatgggatga tattgagttt gtagaggaaa atactttaaa tgtaaatgtt agcaggataa
     4381 ggaaaagatt tgaggaatta ggtatagata atgctgttca gactgtccga gggttaggat
     4441 ataaattaaa taagaattgg taaggagaaa gtatgaagtt atttttaaaa gattataaag
     4501 gttatatttt tatatattat ataggcatag ttatgacaat tatttactgt aatcttatga
     4561 agtttattag ttttggagag agtttatata ttcttttatt tagtt
//
LOCUS       DAYAKB010000152         4541 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.156, whole genome shotgun sequence.
ACCESSION   DAYAKB010000152 DAYAKB010000000
VERSION     DAYAKB010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4541
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.156"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(309..965)
                     /locus_tag="ACGI3L_003647"
     CDS             complement(309..965)
                     /locus_tag="ACGI3L_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199326.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGVRILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(2077..2487)
                     /locus_tag="ACGI3L_003648"
     CDS             complement(2077..2487)
                     /locus_tag="ACGI3L_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199327.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(2703..4085)
                     /locus_tag="ACGI3L_003649"
     CDS             complement(2703..4085)
                     /locus_tag="ACGI3L_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9199328.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVILRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(4096..4455)
                     /locus_tag="ACGI3L_003650"
     CDS             complement(4096..4455)
                     /locus_tag="ACGI3L_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199329.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
BASE COUNT         1534 a          789 c          404 g         1814 t
ORIGIN      
        1 agccattttt tagttataac ttgttttttt agaatcttaa aactttaaat gggggatttt
       61 aagcttctta aaaacagtgc ttagcaactt agatttcttt aaaatattat atttattttt
      121 aagtttaata aaatgctatt ctaacgaaaa acctactttt tatttaaaat ctcacttatt
      181 atttaaaaca ctatccatca cttagaatat tacttcttat ataaattatt atttattata
      241 aatacaaata atattaattt aaaaagttat tcctaattta aataatacta ctatcttcat
      301 cagtgaacct aaactgcaac tttagactta ttagctaaag ccaatattag acctaaagct
      361 atagatgcaa atgcagaagc aattactcta tactcagcag ggaataaaaa tacaattgta
      421 tgacatggta tccagaaaaa tggtatagtt tttaaaacac taaaaccaag gtaagcattc
      481 cagtccacaa tatttaccac atctttaagt tttaccttaa tcccctttcc aacctcatat
      541 tttttatcta taaaacagtc cataacctta tggaataaaa atacagttgg tgacattagt
      601 atattcatag ttgcactctt aaatagagca tttgcaaaag ctattccctc aaatggaagc
      661 ataccatcca cttgtgcttg acctacacct gatgagtaga ttgacattcc atatgtggta
      721 actacaccta ttattcccca aactattgct ctataaaata ctcctactgg tattttccaa
      781 tccttataca aaattctaac accaagtaaa tctcccattg tagctaatac agcaaacttt
      841 aaaaaacctc caatatatgg atgtgcacct gttgcttcca taaatacttc tctactactt
      901 ggtattgcta agacagcaat aatacaaata agaactccac tccatataaa atcgcctttt
      961 ttcatattta taaatactat ttaatatata aatagttctc ctttctatta aagatttatt
     1021 taatttacaa tctatctaca attatttatt aatcacttat tattagatat tcattttcca
     1081 tatttaaatt tattctatcc ctttatctat ttattttctt actactctat ccaccattat
     1141 ctatatattt attttacgat tactctttca ccctaaccct ttaactatct attttttctt
     1201 actattctta tccacatcat ccatatattt attttacgat tactctttca ctctaaccct
     1261 ttaactatct attttttctg atattcttat ccaccatcat ccatatattt attttacgat
     1321 tactctttca ccctaaccct ttaactatct atttttttct ggtattctta tctactatta
     1381 tctgtatatt tattttatga ttactctttt aacctacccc ctatacttta tagtaatatg
     1441 tttttaacct ttttcattat tcccaatatg ctttataact acaaatactc tcccccctta
     1501 aaaataataa taaaattaat caataaattt ataatcatat tattactcta tgtattaagc
     1561 aattactatg ccaataaact ttgatttttt taaacaaatc ttaaaaatcc taaaatgcta
     1621 attttcttta acttttaatg aatctaatag ataacattta attttcgtta tatttttcag
     1681 aatatttcta ttattatttt taagaaaaaa aaataatgtt aacatttctt aacatacatt
     1741 aaaaaatgtt aacattataa attgggttta atacttttac tttgactcga tttactttta
     1801 ttctacttct tactttattt ttaacttaga ctttattttt ttattactta tttgagtctt
     1861 atttatttta ttctcactcc atatgttcaa ttacatttgt ctaaattctt tgatactttt
     1921 attacataat tttaacaagc ttaagtgtta tttgggtagt gcagttgata attatttaaa
     1981 taatcatcaa ctgcatgttt atatcattac agtagcttaa tgtatttaat catacttact
     2041 taggattttg aaatatctta gagattatat ttaacattag tcaattgctg cataattgta
     2101 agcaattgaa atttgagacc catcttcatt ttctatagtg ataggcttca taatttttaa
     2161 tccttcagtt tttatctttt ctaattcttg ttccattttc ttaattgttt cctcaaggtc
     2221 tttttgactt acatctttga ctgcattagg gtctttagca tagtctttta attcttgaat
     2281 atgtttagca tactcttcat aagtataatg ctcaacacca tacttttcca attcagtagg
     2341 gtcagttatt cctgatttta ttagagattc aaatttaggt aaagcaatat tagatgaatc
     2401 atttccattt gcaaatactg ctccagttcc tcctagtacc attgcagata ccatcattgc
     2461 acttataagg gattttttta ttttcataac caatcttcct ttcttagaga tttatttggg
     2521 tagtgtagtt taaaatgact attgcaatag ttatcaacta cactcttaga ctatcacagt
     2581 agtcatgttt atgtcaagcc tttttaaaaa acttttcaat aaaaaatact atctcaaagc
     2641 aaaattaatt attttgagat agtattttaa ttctaaatct tttatattac taagatttat
     2701 ggttattcta tccatgttct atattgttct ttattaactg ctaacaaatt cccttttctt
     2761 aatatgacaa agcgattatc attatagcca cttcgctcaa ttgaaacttc tcctgaatca
     2821 gtataaagta catccttact attactagat ttatttacat acgtttcttc actattctca
     2881 gaattagtta ctttgctcat agatgattct tcatgctctc taaattcaat tacagatact
     2941 tttgccgtac taaaatgagt ctctccatca cttttagctt tactaacaag aatatcagat
     3001 tctactttgg gagaatataa atcagttgat ttactactta ttgaaaatcc aattttatca
     3061 ctttgttcat tttttgttaa accaaaagat tcaacctcat taatctcttt attttctgtt
     3121 gcaaaaacaa gacctgtccc acaaactaat acagttgaaa ctaaaaaagt aacataagtt
     3181 gattttttaa atttcataat attaactatt ctcttttcta tttttgtctt tccaaatcca
     3241 ctacatattg tcattgaaaa tggattattc tcctctgcta gacttattag tgtggttgca
     3301 taatcagccc tatattcttc accaagtata ctcataacct tttcatcaca actaaattct
     3361 atgtctttat ttagtaaaaa aaacatcacc caaactaagg gattaaacca atggacaaca
     3421 agagctacaa gcataaataa ctttaacaga ttatcaaagc tattaatatg aaccatttca
     3481 tgagttaaaa caaagtctaa agtttgatta ttagcataat tcatttgctt tggcaaaata
     3541 attcgtggtt ttaaaatacc agatgtaagt ggtgtcctag taaattcaga tatgcaaaca
     3601 ataaatcttc taaaacggct attcttacac atccattttt taatgaactc atgatttttt
     3661 atatgaattg aagttttaaa aagattaatt attttaaaat atctaaagca taaaagtatg
     3721 ctaaacataa tagtaactat aaaagacaaa atgcccaaca tttccaacat cataatattt
     3781 tcaatattag acattatttc aaattcgtca gaattgtttt tacctgtaga gtcactagct
     3841 ttcttaagag tataattttc tgttgatgta ttacccaatt ccacatcaaa agtcgattca
     3901 attatactat aaatactaaa accagaattt aaacttactg gtattagaag tttaaataaa
     3961 acaatcaacc acaataatac aaataccttt ttaggtaatt ttttaaataa acatgctctt
     4021 ataaaaataa ctattaaaag taatactcca gaagtaaaac tcatttctaa caatttaatg
     4081 aacataaatc ttacctcact ttaatttttc aacaatttgt ttaagttttg taatctcatc
     4141 acttgaaaga ttttctttat taataaaagc tgaaagaaat ttttctgaag accctccaaa
     4201 cattttatta attaaagttt ctgtttcctg tttttgtact tcctctttgc ttattaaagc
     4261 tttacaaaca aaattcggct caattctctc tattgcacct tttgacacta atttttttat
     4321 aacggtatac gtagtgtttc tattccatcc tgtttcttct tttaaaattt ttactaactc
     4381 tccagccttg ctttctcctc tctcccatag aacttccatt actttaagtt ctgaatcaaa
     4441 taattttatc tccatataaa atcgctcctc aaatatagtt atcacaatag tcattactat
     4501 aataaaaaac tatcatagta gtctatacta tgtcaatcat t
//
LOCUS       DAYAKB010000153         4418 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.157, whole genome shotgun sequence.
ACCESSION   DAYAKB010000153 DAYAKB010000000
VERSION     DAYAKB010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.157"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            53..721
                     /locus_tag="ACGI3L_003651"
     CDS             53..721
                     /locus_tag="ACGI3L_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFG9199330.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            880..1386
                     /locus_tag="ACGI3L_003652"
     CDS             880..1386
                     /locus_tag="ACGI3L_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFG9199331.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1514..2530
                     /locus_tag="ACGI3L_003653"
     CDS             1514..2530
                     /locus_tag="ACGI3L_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFG9199332.1"
                     /translation="MGYYNDNDNNKIRRKKISNSKDSNKKSKHSYTPANKKNKSSKTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     regulatory      2726..2820
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            2884..3588
                     /locus_tag="ACGI3L_003654"
     CDS             2884..3588
                     /locus_tag="ACGI3L_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HFG9199333.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3883..4362
                     /locus_tag="ACGI3L_003655"
     CDS             3883..4362
                     /locus_tag="ACGI3L_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFG9199334.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1848 a          372 c          760 g         1438 t
ORIGIN      
        1 aatatatatt atattaggta ttttaaataa attttttaaa gggtgatttt ttatggaaaa
       61 tataactagt tattttacaa caatactatg tgtatttata tgcttatcat ctgtatttat
      121 atttactcaa ctagctagag tatttattaa taagaagaag attaatcaaa aaattaaatc
      181 aagaaacgga tttaggtatg atagagattt tattgaagcc agaagagaag aaatacatat
      241 aaaggataac aataataata aaaataagag taacaataag aaattaaagg gagaaaaagt
      301 atttaaatac gataatggtg atttatataa aggtgagttt gttgatggaa agaaaaatgg
      361 atttgggata tatatttttt caagtaagga aaagtatgaa ggattatgga aagatgacaa
      421 gatgcatgga ataggaaaat atacttatag agatggttca atatatacag gtgaatttaa
      481 atacggatta aaaaatggtt tgggaaaatt aacatatccc aataatgaca tttataaggg
      541 atatttttta gataataaga aaaatggtaa gggtgtatta tataaaaatg atggaaataa
      601 acaagcagga atatgggaag atgatgaaca atgtaaaagt ttagatttta aagatttaaa
      661 taataataaa ataaataatg tttatcaaaa tagattaaat aacaataaat taaaagttta
      721 attattctaa taaaaaaatc tttatttatg atggaatata ggatatatct atgttgtaat
      781 ttgtaaaatc ttcctatatc atataaaatt aagtattgat tagtctatta cataaatata
      841 gaatataaat atatccattt aataataagg agaagagata tgaaagagta tgtagttgtg
      901 gatttagaaa ctacaggatt agatccatat aaaggttgtg aaataataga aataggaata
      961 acagaaataa aaaatgaaca aattgtaaaa aactattcaa ggttgataaa acctaagggg
     1021 ataatttctt catttataac agaattgaca catataagta atgaaatggt agaaaatgaa
     1081 gaaccactag aattagtttt acctagattt agaaaataca taggtgatag aactataatt
     1141 gcacacaatg cgaaatttga tttaaaattt ttaaattact atcttagaat gttagattta
     1201 gaaccaataa acaattatat atgtacagta gagttattaa aaaaatgtaa aagttataaa
     1261 ggaaaaaaca agaaacttga aacagcttgt gcttattaca acatagagaa tataaatgct
     1321 catagagctg acagtgatac attagcaact gcaaaactat ttttgaaaat aaaagatgaa
     1381 tattaattat aaatatagag aaaattagtg aaaatatcct ttataaaatt gacccttaag
     1441 cttacaattt tgttctttga tttattttgt agaacaatgt ataatgtacc ttatatgaag
     1501 aagggagact aaaatgggtt attacaatga taatgataat aataaaataa gacgtaaaaa
     1561 aattagtaac agcaaagata gtaataaaaa atctaaacat tcttatactc cggcaaataa
     1621 aaaaaataaa agttctaaga caagttctag taaaagaatg agtgaaaaag tagattcaca
     1681 gaatcttata aaaagagata gagatagttt tacaagagat aatgtaagac ctttaaatac
     1741 agattacaat caaagagaaa gaagaagagt cgagtataaa caaagagaga aaaaattaaa
     1801 aagtaaaaaa agaaaaaaac aaaaaaggat tagaatagtt agagcattat tatctattat
     1861 gttagttgca ctaattatat tttcagtggc aggtgcaata tttacagttt cagctataaa
     1921 agggtcacca gaagttacta aaaagttaat taggtctaaa tatataagta gtgaggttgt
     1981 aagtataaaa caaatgccaa atgatttaaa acatgcaata gtttccatag aagatgagag
     2041 attttataag cataaaggag tagatgttat ttctctagtt aggtcagtat taaacaatgt
     2101 gtttacagat acaacacaag gtgcaagtac tatagatatg caagtttcaa aaaacctgct
     2161 tactagtaat gataaaacta tgaagcggaa aataagggat atgtataatg ctaagcagat
     2221 gaataagatt atgactaagg atgaaattct tgaagcatat ttaaataata tgtatctagg
     2281 taaaaatgca tatggagctg caaagggagc tgaagtctac tttggtaaaa aagttagtga
     2341 attaaattta gctgagtgtg ctatgttagc tggtatgaca aataatcctg caaggtatat
     2401 tgaccatgga gaggctaaga agagacaagt gattgtactg tataagatgc atcagcttgg
     2461 ttatataact gataaggagt atagaatagc aaaagctgat gacactccat ttaaatcaga
     2521 aattgattaa aattgtaaga atatagtatt ttcaatagtt taaacaaaca aaaatgtaat
     2581 aaaaaaggtg atttgccacc catttgccac cataattata atctaatggc aaattgtttt
     2641 aatgtacaaa ctagataata gaatattgtc ttaaatgcta tattatgcta aaatttaatt
     2701 gtattttgta aattaaaaaa cttataattt agttttctag ggttccgcat tttataatgg
     2761 tcaggtccaa gagaaaacgc gcaattgttg tgtacacgga aggataaaag cctgggagat
     2821 atttaagaat atttctatag gcttttttat ttttacatat tttaaatttg aggaggtttt
     2881 ctaatgaaaa aatttgttat tgaggatgca ttttggaatc tatttcctag tgcaaaaatt
     2941 ggagttgtta tttgtaatga tatagataac tctataaaag atgaagacta taagaaaata
     3001 attttgaagg gagaagaaga agcattaaaa tacttggagg actcagaatt tagcaacaac
     3061 caagtgatta aagtatggag agaagcattt aaaaaattta aaacgaaaaa aggagcaagg
     3121 tcttctattg aagcattatt aaaaagagtt cataatggaa ataatatagg aactattaac
     3181 cctttagtgg atatctacaa ttttatctca ttaaaatatg cattaccttg tggaggggag
     3241 gatatagata aatttatagg agatattagg ctaactagag caattggtaa tgaggagttt
     3301 atcccactag ggacagatga aaattcattt ccatatgaag gagaaataat ttataaagat
     3361 gatggtggag caatttgtag atgttggaat tggcgtgaag cagtgagaac aatgcttact
     3421 gaagatacta acaatgcctt tttatgcatt gaattagtag atgaaagtag atttaaagaa
     3481 tttgaaaatg ctttaaatga attagctaaa atagttcaag aaaaattggg tgggaattgt
     3541 aaaatttcaa ttttagatat tgataataaa gaggtatcag tggattaata tggaggtgct
     3601 gttgtaatgg actattctag ttataaagat acttatattt agggtaagaa ggtctatttt
     3661 agatataacg attatcaaag gatataatat agaaaataaa aatgtagaat ataaaaagcc
     3721 tttaaaataa gaaaaaaatg tattttaaag gcttttatta tactcttttt tatttgcata
     3781 attaacaata aaaatatatt gttaattata atatttttat tgaaaaacga tataatataa
     3841 tgtattatac tatatataaa atattttaaa ggagttggca tgatgtctaa taaacttata
     3901 aaaaatttac taagtggtat attacaaatt ttattttttc ttttaggatt agtaattgtt
     3961 gcaggaggat ttaaaagttt tatgtacctc tgttttagtg gagaagcaac tctacaaggt
     4021 actatttatg gaatattaat gtttatttta ggtgtatcat attttatcat tataaaatca
     4081 ttgatagaag tattaggtag ttctgaatat agcctatttg taaaagagaa tgtaaaaaga
     4141 tttaggatta ttggatatct tttgctttta aactctctaa ttgagtttat ttcaactttt
     4201 ggtactactg gaaaaggaat gagatttcta gatttaggat ttggatttta ttttactgtt
     4261 ccagtatttg tatattttat aacttctctt atgagttttg taattgcaga tggatttgta
     4321 aaggcaataa agataaaaga ggataatgat ttaactattt agatgtgaca ctttaatata
     4381 taggagataa ataacccgaa aagagtgact aactagta
//
LOCUS       DAYAKB010000154         4400 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.158, whole genome shotgun sequence.
ACCESSION   DAYAKB010000154 DAYAKB010000000
VERSION     DAYAKB010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.158"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            231..1310
                     /locus_tag="ACGI3L_003656"
     CDS             231..1310
                     /locus_tag="ACGI3L_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFG9199335.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIVKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="ACGI3L_003657"
     CDS             1634..2002
                     /locus_tag="ACGI3L_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HFG9199336.1"
                     /translation="MNVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKSLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="ACGI3L_003658"
     CDS             2119..2922
                     /locus_tag="ACGI3L_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9199337.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDRQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYMGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3314..4204
                     /locus_tag="ACGI3L_003659"
     CDS             3314..4204
                     /locus_tag="ACGI3L_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9199338.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDSCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
BASE COUNT         1678 a          482 c          828 g         1412 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagccttta
      601 tcatcaagga cgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggct gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacccg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgtaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctac taaaaaaagg caatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagcc atataaatta gaatttgtag
     1621 aggagaaata taaatgaatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaatca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccag atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gatagacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaattgttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gttacgaaaa aaaagaactg tgtcatctca tgtatatggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaactaca tactcattag
     2941 gtaaattatg tagtatatgt gtttacagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat atataaattt
     3061 ttaagcgaaa tacatcaaaa gaaggattag aattagtgga gacagaacag ctattataga
     3121 ttataaataa atagttttaa aggagaggta ctacgaatat agaggaaggt aaatcatacg
     3181 ttattcaagt attataaatg attagtttaa aagtactatc ggataggagt ctccatattt
     3241 aaaccttagt aaaggtagtt aaagtagtag tttaaaaact aaaaaattat ataaaggaat
     3301 taggtataag aaaatgattg agagtatacc agcaaaacaa attttacaaa aagtgaaatt
     3361 tgacaataca agatggtttg gaattgacta taatatgaat ctctatcgtg gttgttctca
     3421 tggatgtata tattgtgata gccgtagcac aatatacaac atagagaatt ttgacaaagt
     3481 tagatataaa gaaaatgtga tagaaatttt aagtaaagaa ttgcgttcaa aaagaaaaaa
     3541 aggtgtagta ggcattggag ctatgtctga cacatataat ccttttgaaa agcaactttg
     3601 tattacaaag caagcactag atttgatttc ggaaaatcat tttggagtgt ctattgatac
     3661 taaaagtagt ttggtggtta gagatatacc gattttgcag aaaattaaaa aaaataattc
     3721 tgctattgta aagttgacta taaccactgc aaatgatgaa ttatcaaaga aaatagaacc
     3781 ttatgtaaat ccaagttctg tacgatttga cgcagtgaaa gaacttaatg attctggaat
     3841 tttttgtggc atattattga ctcctatgct tccatttttg actgataata aagatgaaat
     3901 acgagcaatt gtagaaaaag cacacaaggc taatgcaaaa tttatttatt gcatgtatgg
     3961 tgtaacaatg cgtagtggtc agagagagtt tttttatgag catttaagag atatatcacc
     4021 aaaattggta cttaaatatc agaaaacata tggtttaaac tatgtatgta ctgtacaaaa
     4081 taaagattct tgtgagaagt tgttaagaga agaatgtgca cgttatggta ttttgacgga
     4141 tatgaaagat attataaaag cgtacaagag gtcggagtca tatactcaaa taaaattttt
     4201 ttaagatagg ctttggatga gatataatag tgttgattga tgtgttgata ttatagttga
     4261 ttgttagaga ggatattata gatgaatatt agtattgata ttttaggtaa ttgttagagc
     4321 tgatattata gatgaatatt agtattgata ttctaggtaa ttgctagagt tagtattata
     4381 gatgaatatt agtattgata
//
LOCUS       DAYAKB010000155         4368 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.159, whole genome shotgun sequence.
ACCESSION   DAYAKB010000155 DAYAKB010000000
VERSION     DAYAKB010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4368
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.159"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..849
                     /locus_tag="ACGI3L_003660"
     CDS             <1..849
                     /locus_tag="ACGI3L_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9199339.1"
                     /translation="IYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQ
                     HKLYQSMIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDR
                     LNKGLDMAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFT
                     YVYTDVKWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDL
                     KRVFDPFFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDV
                     NSLIKV"
     gene            1117..1968
                     /locus_tag="ACGI3L_003661"
     CDS             1117..1968
                     /locus_tag="ACGI3L_003661"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFG9199340.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            2072..2818
                     /locus_tag="ACGI3L_003662"
     CDS             2072..2818
                     /locus_tag="ACGI3L_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199341.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALLRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            2818..>4368
                     /locus_tag="ACGI3L_003663"
     CDS             2818..>4368
                     /locus_tag="ACGI3L_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199342.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVIMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKSISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFI"
BASE COUNT         1681 a          436 c          754 g         1497 t
ORIGIN      
        1 atatataagt attataaaaa tagagaagta tataatctgt ttgaaaaagg agtacattct
       61 ttggaggagt catttttgta tttaggaagc tcattcttgg ggagaaatat atcagttatt
      121 ttaaaacaac aacataaatt gtatcaatca atgatacaag agcataaaaa gatacatagt
      181 gaacatttaa ctttcatcaa ccaatggatt catcagatga aaacaccaat atcagttata
      241 agccttcagc ttcaagatta tgagggagaa gaagtaactg aaaatataag aaaagaaata
      301 gatagattaa ataaagggtt agatatggct atgcattttg caagggcaga taattttcag
      361 aaagacttta tagttgaaaa agccaaatta aatgaaattg tatctagtat tgtaaatgaa
      421 gaaaaaaggt tatttataaa aagtggaatg attcctaaga ttcaagtaga caaatttact
      481 tatgtttata cagatgtaaa atggatgaaa tttataatag gtcaattaat tacaaatgga
      541 gtgaaatatt ctaaagatta tagtaactac ctaactataa aatctgaaga aaataataaa
      601 tatgtaattt taagtataat agatgaagga attggaattg tttctaaaga tttaaaaagg
      661 gtatttgacc cattttttac aggagaaaat ggtcgtaagt ttggagaatc tacaggtatg
      721 ggtctttatc tagtaaaaaa ggtatgcgat gatttaggtc ataaagtaag tataaaatca
      781 gaagtaggaa aaggtacaga agtttcaatc tactttaata aagatgtaaa tagtttaata
      841 aaggtgtaaa tagtttgata aagatgtaaa ttatctgtta caatagggtt tttagttaat
      901 tgtacttttt tattatacaa tttattaaat gaaatattca tagttaaata atcaaaattt
      961 aagagcgttt atttgcaaac cttacataga tgtaaggttt gtgtaatgtt tgcagatagt
     1021 taaattttct aatctaaatt acaattaata taagaaataa cataagagaa ataacataaa
     1081 aaaagaaatt ttgtaaaaaa ggaaggatgt ttattgatga gtttagatgt tatttttata
     1141 ttgaaatcag tcataatagc tatagtagag gggcttacag aatttattcc agtttcatct
     1201 acaggtcata tgattttggt tggtaattta atagatttta aggggcaatt tgctgaaatg
     1261 tttgaggttg taatacaact tggggctata ttagcagtag tagtacttta ttggaaaaag
     1321 ataaaagata gcgttataga attttttaaa tttatattta ctggtggaaa agaaggaaag
     1381 attggtttta gatttggaat gaatgtaatt ataggttgta taccatttgc gattatagga
     1441 gttctatttt acgataatat aaaatcattg tttaatttac aatctgtaat tataggattt
     1501 atagtgggtg ggattttatt attagtagta gaaactttgt ttagaaaaaa gaatcattcc
     1561 acagataata tagataaaat tactccaata caagctttaa aggttgggac attacaagtt
     1621 ttgtctgcat ggccaggtat gtcaaggagt gcatctacta ttatgggtgg atggatagca
     1681 ggacttaatt ctcctacagc agctgagttt tctttctttt tagcagtacc agctatggtg
     1741 gcttcttcag gaaaagattt atttgaattt gattattcaa taatgacacc aacattgtgg
     1801 attgctttgg tagttgggtt tatagtagct tttattgtat caataatagt tatggaaaaa
     1861 ttcgtgaatt ttttaaagaa aaaaccaatg agagtgtttg ctgtatacag aataataatg
     1921 ggtgtagtac ttgcagtatt agcttttact aacataatta gtgtatagaa aaaatagatt
     1981 tatcatctat aaaaattaaa ctaagataaa ttataattaa caattatata tatgttattt
     2041 caaaaattaa attaggaagg atagttaaat aatgaaaatt ttaactgtaa ataatttaag
     2101 taaagtatat ggtaaaaaaa taattttcaa cgcattaaat gacataaatt ttagtataga
     2161 agatggagaa tttgtaggaa ttatgggtcc atctggtagt ggaaaaacta ctcttttaaa
     2221 tatgatttct actattgaca agccaactac aggaactatg gaattaaagg gcaagaatcc
     2281 tttattgtta agaggtgagg aacttgcatt acttagaaga agagagttag gttttgtatt
     2341 tcaggatttt aatttattgg atacattaac tataggagaa aatatagtat tgccattgac
     2401 attagataag gtcagtgtaa aagagcaaga tgagagattg aatgaagtat ctacaatatt
     2461 aggtataaaa gatttattag gaaaaagaac ttttgaagta tcaggtggtc aagctcagag
     2521 gactgctatt gctagagcat tgattaacaa tccatcaata cttttagcag atgaaccaac
     2581 aggtaattta gattcaaagt catcaaaggt tgtaatggag ctatttcaaa agataaataa
     2641 agaaaataaa gttactacta tgatggtaac tcatgaccca ttagcagcga gctactgtag
     2701 tagaatctta ttcataaaag atgggtctat atataatgaa atatataagg gtagtagtag
     2761 agagcagttt tatcaagaga taatggatgt acttacatta ttgggaggcg ataactaatg
     2821 aatataaaac agtttgctat taacaatatt tcaagaaata ttaaagcgta tttaggatac
     2881 ttagcaagta ttgttatatc atcttcactg ctattttctt ttattatgtt tacaagtcat
     2941 ccagatttag atgtatctca atttcctgat tatttaaaag aaggtctcaa gatgagtaag
     3001 ataattgcat atctattctt attcttcttt gtgttttatt cagttagtgt gtttcttaaa
     3061 agtagatata aagaatttgg aatactttat attacaggta tatcaaagcg ccaagtaatg
     3121 aaattaatct ttatagaaaa tatgataata aatatagtat cttctgtaat tggaataata
     3181 ataggcttaa tctttgcaaa gatattttta gtgattatgt ctactttttt agaattatca
     3241 ccattaaaat tctatatacc atttaatgcg atattgtcta ctttaatcta ttttatgatt
     3301 ttagctgtat taacatcaat atttacttct tttatagtta aagaaaatca ggtgttgaag
     3361 ttacttaaag gtacaaaaac tccaaaacca gagcctaaaa catcactaat gcttgctata
     3421 ttaagtattt gtttgtttat aatagcgtat tataatgcta ttacctcaac cgaccaatat
     3481 acaacatatc tgcgcttagt tccagttaca tcccttacta tagtagcaac ttacttgttc
     3541 ttttctcaat ttagtgtatt ttttatgaag aagctaaaac taaacaagag attttataga
     3601 aaaaatacaa atatgctttg gatttcgaac ttgatttata aggtaaagga taatgctaga
     3661 atatttttct tgataactat aacttctgca gtagcattta ctgctatagg tacagtttat
     3721 tccttttgga aagatgtaga gcgtcaaatt aatttaatat atcctaacac aatatattat
     3781 tcaacaatga cattgcataa tgaccctaaa aagcctgata gcaaagaaaa agacaaggaa
     3841 agaatgatgt ttatagaaaa taatctaaaa aaagagaatg tagactatac aaggactaat
     3901 ggtgaattta aaactgtatt tcccaagaaa agtgatttta atgtcagaat tatgaaagaa
     3961 tctaagtact tagaaattac agaaactata ggggttaagt ctataagttt tgaagataat
     4021 gaatgtatat cattattatc atcaagttta ccaggaaata ataacgtcaa agaaaatatt
     4081 attgtaggga ataggggttt aaaggtggca aaacaagtgg aagaatgtgt tatgccagca
     4141 tattacaaaa atatgtatgt ggtaaaggat aatttttatg atagtataga atcaaaattt
     4201 atagtggata gatttactgc atttgaagta gaggattcaa gtaaaactat agagatatgc
     4261 agagaatttg aaaataaatt taataatgag tcagggatgc aaccatattt gtttttctct
     4321 aaagaattaa tgataggaac tgggaaatta atgtattcta catttata
//
LOCUS       DAYAKB010000156         4338 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.160, whole genome shotgun sequence.
ACCESSION   DAYAKB010000156 DAYAKB010000000
VERSION     DAYAKB010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4338
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.160"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            123..1004
                     /locus_tag="ACGI3L_003664"
     CDS             123..1004
                     /locus_tag="ACGI3L_003664"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9199343.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(1065..2273)
                     /gene="tyrS"
                     /locus_tag="ACGI3L_003665"
     CDS             complement(1065..2273)
                     /gene="tyrS"
                     /locus_tag="ACGI3L_003665"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFG9199344.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(2346..2598)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(2750..3718)
                     /locus_tag="ACGI3L_003666"
     CDS             complement(2750..3718)
                     /locus_tag="ACGI3L_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HFG9199345.1"
                     /translation="MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFC
                     IICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDD
                     LVYGSVFGLIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFG
                     MVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICVSYLAIFE
                     VLKLLNVKVDSVYLKTIFISITYISLYFIIRDSCMSLQNFIIAKFRKLLYARILFLII
                     ILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            3891..4331
                     /locus_tag="ACGI3L_003667"
     CDS             3891..4331
                     /locus_tag="ACGI3L_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9199346.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKN
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
BASE COUNT         1564 a          670 c          515 g         1589 t
ORIGIN      
        1 gtcatataag ttacacttta gttatcttag ttacaacttt gtcggtttac tttttctact
       61 ttcttcgata taattataat atatttttga tacaattcga caaaaggggg aatgctgtaa
      121 ttatggtaaa aaaaagaaaa aagaaaactg ttacacttac tatacttgtt gtaatagtta
      181 ttggtatttt ttctatggca tgggcggaca tgtctagaaa aaaagaaatg aaagaaactc
      241 aagaaagact taaagctgaa agattagaaa aagaaagaat tgaaaaagaa aaaaatgaac
      301 ctattattgg tgcaaaaaaa gaagctgtaa aagaatatgg atatgacgca aaaatagttt
      361 gggacaaact taacaaatac gactattcaa acaatggaga aaagatagtc tttcttacat
      421 ttgatgatgg accatctact actaatactc cacaagttct agatatcttg aaaagacatg
      481 gtgttagagg aactttcttt attaagggtg attctcttga aagaaaagga gctaatgaaa
      541 ttttaaaaag aacatttgac gaaggaaatg caatagccca tcactcttat actcatgact
      601 ataaaaaact atatcctaac agaagcctaa atctcgatac attcgtaaat gaacttaaca
      661 aaactgatga agctatgaaa aaagtcttag gaaagaattt ttcctcaaat gtagttagat
      721 gcccaggcgg gtatatgtca tggaaaaata tggaacctct aggaaactac ttaaaagaga
      781 aaaacatggc atcaattgat tggaacgctt taaatgctga tgcagaaggt aaaaagaaaa
      841 atgcacaaga attatttgaa catgcaaaga aatcttctga aggcaaagaa atggttgttc
      901 ttttaatgca tgatacttat ggaaaacaag aaacagtaaa tgcattggac caaattataa
      961 catattttaa agacaatggt tatcaattta aaattttaat ataataaaaa agcaagttta
     1021 ttgaatgtac attttatact caatagactt gcttttactt tactctattt tactagctcg
     1081 atttttacaa attttttctt tcctatttga acaactaatt cactctcttt tacaatagtg
     1141 cttaaatcct ctactttttc accatttacc tttactccac cttgagaagc taatcttcta
     1201 acttcactct tactcttaac aatctcatta gaaactagta cttcgattaa gtcaaatcca
     1261 tcttccttaa cttgaattgt ttgtatatct tcaggtattt gacctttttg gaatacagat
     1321 ttaaatcttt cttcagcttc tttagcagat tcttctccat ggtataatgt tactatttct
     1381 cttgctaagt tcatctttat atctcttgga tttactgaac cctctttcaa ctgtgattct
     1441 attttattaa cttcatcagg atgaacatct gtcactaaat tgtagtattt aattataagt
     1501 tcatcaggaa tttccataga tttttggtac attattcccg cttcttcatc tattccaata
     1561 tagttaccta aactcttact cattttttct ttaccatcta atccttctat taaaggcatc
     1621 attattacta tttgagactc cataccaaat tctctttgta atgatcttcc cattagtaaa
     1681 ttgaatcttt ggtcagttcc accaagttct atatcagctt ctaatgctat agagtcatat
     1741 gcttgcatta atgggtagaa gaactcatgt actgatattg gcatttgtcc ttcatatctc
     1801 tttttaaaat cttctctttc taacattctc gcaacagtaa tagttgctgc taattttatt
     1861 acatcttcaa aatttaactt agctaaccac tcgctattaa atcttacaat agttttttct
     1921 ttatctaaaa ctttgaaaat ttgttcttca taagtttttg catttgcaag aacttgctct
     1981 gttgttaaag cttttctagc tttagatttt ccagttgggt ctccaatttt tcctgtaaaa
     2041 tctccaatta ttattactat ttgatgacct aaatcttgta attgtttcat ctttctaaga
     2101 actactgtat gccctaaatg tatatctgga gcacttgggt ctagacccaa ttttactatc
     2161 ataggctttc cttctttttc tgatttaata agcttttccc ttaactcttt ctcatctatt
     2221 aaatcatcta cacctttcat aattattcgc atttgctcgt ctatcgattt catttttcat
     2281 tcctcctaaa atatttatat aatctataat ttttattttt ataataaaaa aagctttcat
     2341 cctcttaaaa ggacgaaagc attgcttacg tgttaccacc ttagttcatc aatatctcac
     2401 gatattaatc tcttagagta caattacata tactcgtgta ctataacgtg tactaatccg
     2461 atatctctta atggttgtta tctttcagag atagtgctct gagatgtatt caaactaaat
     2521 caatttattc catttcacca aactggaact ctctgttaaa taaaatctag ccctacttct
     2581 tctcttcata gcatttatat attcagatta tttcatcaat tacaagaaat ttttcttaac
     2641 ttactcataa tatattatta tttttatatt ttgtcaacct tttttattat tatatacatg
     2701 tttttttaca ttatactact tttttatatt ttttaccaat acccaaaatt tatttttcaa
     2761 tcaaaagatt tatttgttta ttgactatat tactctgact caatcttata tttattttct
     2821 tatttaaaaa tgcgtttata attattaaac caataactgt tacatcaaat ataaaaaaca
     2881 gcaataaaat tattatcaaa aataaaattc tagcatataa taattttcta aacttagcta
     2941 ttataaagtt ttgtagtgac atacatgagt ctctaatgat aaaatagaga cttatatagg
     3001 ttattgatat aaagattgtt tttaaataaa cagaatcaac tttaacattc aacagtttta
     3061 gaacttcaaa aatggctaga taagaaacac atatgtaaaa agcttttttt gagcaacata
     3121 aaaattggtt taaacttcta aaattcttaa atattaaaaa tttttttaga gaattagaat
     3181 ctaaaatatg caatttattc cctaaaatta aacttaataa atatatgcaa aacaccatac
     3241 caaaaggaaa caatgctatc attaaataat aaataaaatt tgtataccca ttaaaataaa
     3301 tccatttgct atatccttga aattctttca taaaactata acctattaat gttgaagcat
     3361 atatatcaat aaaaaccatt acaataagcc caaatactga accatatact aaatcatcca
     3421 taaccattgt aggcttattt attagatagc cacacattat accaagtaat acactctgac
     3481 ttgcccaaat agcagttcct agatttccaa gtaccagaga aattattaaa agcgaagtaa
     3541 ttccagataa aatggtatac tttaaatcac atttcaagca gattatacaa aaaaatactg
     3601 gcactataaa atctaagtaa atagcatatc caaatccagt actcacagct ataattgtta
     3661 ctactatgaa taaagatgac aataaagctg cttcagttaa ttttttagta gtattcaaaa
     3721 cactgcctcc ataaatcata aattttctaa ctaaagtttt gtttttaata tagtatatca
     3781 ctttttaaaa atatttttaa taaatataaa ttttaataaa ggtatttatg ttaaaaatgg
     3841 tataatgtat cttaatattc agttttttaa gatgctagga ggtaattact atgtttaaaa
     3901 ttaaacactt taatgatttg agtttagatg aattttatga aatagcaaaa tcaagatatg
     3961 aggtatttgc ttgtgaacag aagatatttt cattaaacga ttatgatgat atagataaaa
     4021 actcttatca catattttta aaagaaaatg gattgatttg tgcttacgct agaataattc
     4081 ctaaagaata cagctcttat aatgatgttt ccattggtag agttttagtt ctttctagtc
     4141 atagaagaaa aggattagca aaacaaatga tggattgtgc tatagatttt ataaaagtta
     4201 acttacacga aaataatata accttatcag cacaaactta tataaagaac ctttacttat
     4261 cttgtggttt taaagaaatc tcagaagtat acgacgaagc aggtattgaa catattaaaa
     4321 tgagattata gtgttgac
//
LOCUS       DAYAKB010000157         4314 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.161, whole genome shotgun sequence.
ACCESSION   DAYAKB010000157 DAYAKB010000000
VERSION     DAYAKB010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.161"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            347..2446
                     /gene="nrdE"
                     /locus_tag="ACGI3L_003668"
     CDS             347..2446
                     /gene="nrdE"
                     /locus_tag="ACGI3L_003668"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFG9199347.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDKWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            2459..3430
                     /gene="nrdF"
                     /locus_tag="ACGI3L_003669"
     CDS             2459..3430
                     /gene="nrdF"
                     /locus_tag="ACGI3L_003669"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFG9199348.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            3506..4132
                     /locus_tag="ACGI3L_003670"
     CDS             3506..4132
                     /locus_tag="ACGI3L_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9199349.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         1729 a          459 c          790 g         1336 t
ORIGIN      
        1 atcagaatat atttttaagc tatttagaga taatttaaat ttttaaacag gacataataa
       61 gcttgtattg ttttatattt gagttgataa aaatttcttt aaataaaaat aatgtcaatt
      121 ataaagtaat aaaagtttag atataaaaaa atttgtgtat atactatatg tagtatataa
      181 tagataaagc actgactata tgtagtgctt ttgtttttga aaaatactta ttgcatttct
      241 ataattatag attaattttg ggatttcaac tgataagtac caaaagaaat aataagcaaa
      301 ttaagtgaaa ttatggcaca agattatgtt aaaaggacgg taaataatga attggataga
      361 gcttaacaat caagtgataa ttaaaaatga acaaggcaag taccaattgg aaaaggataa
      421 ggaagcctta agtagttaca tagaagaatt tatacagcca aagttgagaa aatttaataa
      481 cctagaagaa agattgaagt atttaataga tgaaggttat tattcaaaag aagtaataaa
      541 tcagtatagc atagatgtta ttaaaaatat atatgatatg attgataaac ataagtttga
      601 atttcaatca tatatgagtg caaataagtt ttatcaaaat tatgcattaa agagcaatga
      661 tggaaaggaa atattagaaa catataatga taaagtgtta attgtagctt tgacactagg
      721 aaatggcgat aaagatttag ctttaaactt ggcagataaa atagtaaaac aagaatttca
      781 accagctaca cctacttttt taaatgctgg aagaaaaagg gctggagaaa tggtatcatg
      841 ttttttacta tctgtagaag atagtacaga aggtatatcg tatgctatat cttcatcaaa
      901 tcacttatca aagattggtg gaggagttgc actaaattta tctaaactta gagcatctgg
      961 cgaatctatc aaagatatag aaggtgcagc tggaggtgtt gttggagtag ctaaaatgtt
     1021 agaacaatca tttagttact ttaatcaaat gggagctaga caaggttctg gtgcggtgta
     1081 ccttactgta ttccatcctg attttgaatt gttgatggat actaaaaaga taaatgcaga
     1141 tgaaaaaata aggcttgcta cattatcatt aggagctata ataccagata aatttatgga
     1201 gttggcagaa aaaaatgaag tagcatatgc attttatcct catactgtgt ataagaaata
     1261 tggagtttct cttgatgaga tagaaatgga taagtggtat gataaactgg ttaatgatag
     1321 tgatataaga aaaaaagaaa taaatcctag gcagatgttg acaaaaatag cacagatgca
     1381 acaagaaagt ggatatccat atgtagtgta catagataca gctaatagag aacatacatt
     1441 aaaagatgtt ggaattatta aaatgtctaa cttatgttgt gagatatttc aatatcaaac
     1501 accttcagaa atagaggggt atggaggaaa aaatgaatgg ggacaagata taagttgtaa
     1561 cctaggttct ttaaacatag ccaatgtaat ggataataaa actatagaaa gtacagttga
     1621 aacagcaata agagcactgt catttgtagc agatagcaca gatataaaac cagtgccaac
     1681 ggtaagcaat agtaacagca agtctcattc tataggatta ggagctatga atttacatgg
     1741 atacttagta agagaaaata ttttatatac ttcagatgat gctatagatt tttctaatgt
     1801 attttttgca atggttagat actattcaat taaagcttct atgaaaatag ctatagaaag
     1861 aaatcaaact tttgaaggat ttgataaatc agaatatgtt aagggaagaa atagcaaggt
     1921 tttatcaaaa tactatgaac aatcttatct acctaagtca gaaaaggtaa gagcattatt
     1981 tgaagggatt tatataccaa caaaagaaga ctggacaaaa ttattggatg aggtaaaaga
     2041 aaaagggata tataatgcat atttaatggc agtagcacca actcaaagca ttagttatgt
     2101 tcaaaatgct acatcaagta taatgccaat tactgagcca gtagaagtaa gaacatatgg
     2161 agactctact acaatatatc caatgccatt tttaacaaat gataatatgt tgtattatca
     2221 atcagcatac aggatggata tgagaaaggt catagattta gtggcaacag ttcaaaacca
     2281 tgttgaccaa ggtatatcaa caacactgtt tgttacagat gaaaagacaa ctagagatat
     2341 agctagacat tacatatatg cctataaaaa aggtttgaaa agtttatatt acacaagaac
     2401 aaagatgaca agagatactc atgagtgtct agtgtgttca gtatagggag agaaatatat
     2461 gacatttaat ttacataaaa tacataatgc agttaactgg aatagagaag aagatggatt
     2521 tacacaagct ttttgggaac aaaatgtaaa acaattttgg cttcctgaag aaatatctgt
     2581 ttctaaagac ataaaggtat ggaatgaact aagtaataaa gaaaaggaat tatataaaaa
     2641 agtattgggt ggtttaacat tactggatac aaaacagggg aataatggaa taccatctat
     2701 gatgagttta acagaaaacc tacaaagaaa agctgtcttg tcttttatgg ggactatgga
     2761 agaaatacat gcaaaaagtt attcttctat atttatgact ctactttcta atttagaaat
     2821 agatgaatta tttgaatgga tagaaacaga accaacatta caaagaaagg ctgatttagt
     2881 tttagctcaa tacgaaaata ctacaaatca agagggatta tacctatcaa tggttacaag
     2941 tgtattttta gagagtttct tgttttattc aggattcttt tatccattgt atctatctgg
     3001 tcaaggaaag atggtagcta gtggagaaat aatatcgctt attcttagag atgagtcttt
     3061 acatggtaag tatataggat tgctagcaca agaaatatac gattcatttg ataaaatgga
     3121 taaggagatg ttagaagaga agatgtattc tatactttat agccttatgg agaatgagat
     3181 agagtataca aatgttatat acagagaaag tgggcttgaa aaagaggttg tgaacttttt
     3241 aaaatacaat gcgaatagag ctttagaaaa tctagggttt gagaagctat atactgtaga
     3301 tgctataaat ccaattgtat taaatggtct tagcactgaa accaaaacac atgatttttt
     3361 ttcaactaag ggtaatggat accaaaaagg agtgtatgag gaattagagg atgaagattt
     3421 tataatataa tttataatta tgacacactg ttgtcacttt tagcgtgata atatcaatgt
     3481 ataaaatata tatggaggta tttttatgaa atatgaatgg agaaaaagag ataaagagtt
     3541 atatttacct aaaaagaatc ctgtaatagt tgaaatacca gaacagaaat ttatcatgtt
     3601 aaaagggagt ggagacccaa attctaaaga atttactgaa gcaataggag tactttattc
     3661 tttggcatat gcaataaaaa ccatgcctaa aaaaggaatt gtaccagaag ggtattttga
     3721 ctatacggtt tttcctttag aaggtatatg ggataaggga gaaaaaagta aaggcttaga
     3781 tgtacttatt aaagaagatt taatttacac tataatgata cgtcagccag attttgttac
     3841 acaagacctg ttggataaag ctactgatat agtaaagaag aaaaaacctc ataatcttct
     3901 tgaaaaagtt agatttgggt ctattaatga agggctatgt gttcaaatgc ttcatatagg
     3961 ttcatatgat aatgaaccag aaagctttga cattatgaac gaattttgca aaaaaaataa
     4021 acttataaga aaatcttaca cacatcgtga aatttatata agtgatgcta gaaaagtatc
     4081 gcctgaatca ttgaagacgg ttttacgttt tgaagtagaa agggaagtat aaatattttg
     4141 aataatttat aagagttata aaaagtgaag tctgttgaga cttcattttt tgatgcaatt
     4201 ttaaaattaa atttgatgtt tcataatatt ttaaaaactt tctactttta ttagtgtgaa
     4261 taactgttgc tattaaataa taatactaat tatataagta ttattatata atat
//
LOCUS       DAYAKB010000158         4293 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.162, whole genome shotgun sequence.
ACCESSION   DAYAKB010000158 DAYAKB010000000
VERSION     DAYAKB010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.162"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..2513)
                     /gene="carB"
                     /locus_tag="ACGI3L_003671"
     CDS             complement(<1..2513)
                     /gene="carB"
                     /locus_tag="ACGI3L_003671"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HFG9199350.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNP"
     gene            complement(2706..3755)
                     /gene="carA"
                     /locus_tag="ACGI3L_003672"
     CDS             complement(2706..3755)
                     /gene="carA"
                     /locus_tag="ACGI3L_003672"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFG9199351.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(4012..>4293)
                     /locus_tag="ACGI3L_003673"
     CDS             complement(4012..>4293)
                     /locus_tag="ACGI3L_003673"
                     /inference="COORDINATES: protein motif:HMM:NF014225.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199352.1"
                     /translation="NSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGND
                     STRDGFKIRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
BASE COUNT         1234 a          844 c          437 g         1778 t
ORIGIN      
        1 gggttaacct caattatata taattcattt tgaaattcta taaactgtat attaaccata
       61 ccaagcacat taaggtctaa agctattttt ttagtgtatt ctactatctt ttcttttatt
      121 tcatcagata tattttgact tggatacatt gttgtactat ctccagagtg aactccagct
      181 ctttctaaat gctccattat accaggtatc aatatatctt ctttatcaca tatagcatct
      241 acttctattt ctctaccagt tagatattta tctataagta ctggattttt atggtctcta
      301 tcaaatgcat catccaaata ctgaattagt ttttcttcgt tataagttat ttccatacct
      361 tgaccaccaa gtacataaga tggtctaact aatactggat aacctaactc cttagcaatt
      421 tcaacacctt cattagttgt ccatacacct tttccttttg gtctatttat atctagtctc
      481 tctagtaaat catcaaattt ttctctatct tctgctgcat ctatatctct aaagtctgtt
      541 cccagtatag gtatattttt ttcatgtaaa aacttagcca attttatagc tgtttgtcca
      601 ccaaactgta gtattacacc ttctggtttt tctttttcta ttatatttaa aacttcttct
      661 tctgttaatg gttcaaaata caacttatca gatgtatcaa aatccgtact tacagtttca
      721 gggttattgt ttacaattat agtttctatt cccatttttc ttaaagattt tacacagtga
      781 actgaacaat agtcaaattc tattccttga cctattctta ttggaccaga acccaatact
      841 acaacttttc tcttatcact aactactacc tcatcatatt gttcataagt tgaatagtaa
      901 taaggtgata gagcttcaaa ttctcctcca catgtatcaa ccattttata aactggttgt
      961 atattatata aacttctcaa ttcatataat ttttctgggc ttatcttcat taagtcagat
     1021 atacctttat cagaaaatcc ctttttcttt aattcatgta aatattcttt atctaagtct
     1081 tctattttta gaacttttaa cttttcttct tgttctacta tccatttaaa tttatttata
     1141 aaccacttat caacaccagt tatttctgat atcatttcta ctttatagcc tcttcttatc
     1201 atttcagcta agtcaaatag tctctcatca tcaggtacta ctactctagc ctttaattct
     1261 tctaatgttc taccttctga tggagcatga accaatgaat attttcctgt ttcaagtgat
     1321 cttatacctt taagaatagc agcctcaaag ttacttccta tactcatgat ttcaccagtt
     1381 gccatcatct tagttcctaa ttttctattg gcatgtctaa atttatcaaa tggccacttt
     1441 ggtattttta ctaccacata atctaatgtt ggctcaaaac aagcataagt ttttttagtt
     1501 actgcatttt ctatctcatc caaagtataa cctaaagcta tcttagctgc tacttttgct
     1561 attgggtatc ctgtagcttt tgatgctagg gctgatgacc tactaactct tgggtttatt
     1621 tctattatcg catattctaa actatgtggg tttaaagcta tttgaacgtt acatccacct
     1681 tgaacctcta ttgcatttat tatgtctatt gatgcctttc taagtagttg atactcttca
     1741 tcacttagag tttgacttgg agcaacaact atactgtctc ccgtatgaac tccaactggg
     1801 tctacatttt ccatattaca tacagttata cagtttccat ttccatctct cattacttca
     1861 tattctattt ctttccaacc ttttatactc ttttcaagaa gaacttgtcc aacaggactt
     1921 agctgtagtc catgtgaaag tatttctctt aattcttcct cagtatcagc tatacctcca
     1981 ccagttccac ctagcgtata tgctggtctt acaactactg gatatcctat cttattggca
     2041 aactcaagac ctgcttctaa atttgtaact atatcactaa ctattactgg ttgatttatt
     2101 tctttcatta cttctctaaa taaatctcta tcttcgccct tttttataga ttctatagat
     2161 gttcctataa cttttacatt atatttatct aatataccag catcatgtaa ttctacagct
     2221 aagtttaatc ctgtctgacc acccatacct gcaagtaaac tgtctggtct ttctttttct
     2281 attatttttt ctataaattc tattgttaat ggttctatat atattttatc tgcaatttct
     2341 ttatcagtca ttatagtagc tgggttacta tttactaata caacttcaat tccctcttct
     2401 tttaatgctt ggcaggcctg tgttcctgaa tagtcaaact ctgcagcttg acctattatt
     2461 attggccctg accctaatac taaagttttc tttatactat ctaatttagg cataactctt
     2521 tctccttatc taaacaattt tcacagttct tatcttcatc atctatacaa tcaactttaa
     2581 ttactttatt ttatcttaag ttcaaattta ctcatcaata catctattta atacatctat
     2641 gttaattaaa ccaaactttt tgatttaagt tattcttgtt ttttagttag ctattctaat
     2701 gttgtttatt ttactaattc taaaaattta tcaaaaatat agtcattatc ttttggtcct
     2761 gggcaagctt caggatggta ttgaacactg tatacatcta gcttctcatg tcgcattcct
     2821 tcaacagtat tatcatttaa atttatatgt gtcactttca tttgttcagg aacttctgaa
     2881 acataataac catgattttg agaagttata aatacttttc cttcttctaa atctttaact
     2941 ggatgatttc cacctctatg cccaaattta agtttagcag tttttcctcc aagagctaaa
     3001 gctaaaagtt gatgtcctaa gcatattcca actataggtt ttttaccaat aagagctttt
     3061 atattttcta taacatcttc taagtcttct gggtctccag gtccatttga caagaatatt
     3121 aagtcagggt ttatactcaa tacatcttct ggagatgttg tagctggaaa tattgttata
     3181 tcacatccac gagctataaa tgatcttaat atatttcttt ttactccaaa atccataaca
     3241 gccacttttg gaccatttcc ttttatatgc tctacttctt ttcttgtaac agttctaact
     3301 gcttctgtat ttgaaaactt atccaattta tgtttaacat cttctaattt actgtcttct
     3361 aatgtaatta tacctttcat tgttccatta tttctaagta tcttagtcaa agctcttgta
     3421 tctattcctt caagtccgat aactttattt tgctttaaat attggtctat atcaatttca
     3481 catctaaaat tacttggaga atcacttttc tcccttacta tgaatccctt tacttgaact
     3541 ttttcagact ctgctgatga taaatttata ccataatttc ctacaagagg ataagtcata
     3601 gtaactattt gaccatagta agaagggtct gttaaaactt caccatatcc tatcatcgaa
     3661 gtattaaata ctacttctcc tacactttct tctaaatatc caaatgcctt tcctataaaa
     3721 actgttccat cttctaatat taaccttgct ttcatactac agtacctcct ataattctct
     3781 ttagacaaac taaagaacat taactaaata taagctttta aatatctata tctatttttc
     3841 acttttacat tctagtttta tacttattta catttatttt ttatcttttt ctattatact
     3901 acaaatttct taaaaaaaag aagttatctc aaaagtaaaa actcctagaa aaaataacct
     3961 ctttttttta tttaataatt aaattcttaa actatacaat caacttaatt tctattcagc
     4021 tatattgtaa acttttaact catctttatt taaatgtttc ttcttaactt ctactaaagc
     4081 ttttagtgta tccaaagatg tcattatttc agtagaaaat tcaatagctg ttcttcttat
     4141 cttaaatcca tctcttgtag agtcatttcc tttagttggt gtatttatta ctatatcaac
     4201 ttgtttattt cttatagcat ctaatatgtt tggtctagat tcttctactc tatttactat
     4261 atcagcctct attccatttt ctcttaagct att
//
LOCUS       DAYAKB010000159         4227 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.163, whole genome shotgun sequence.
ACCESSION   DAYAKB010000159 DAYAKB010000000
VERSION     DAYAKB010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4227
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.163"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            8..382
                     /locus_tag="ACGI3L_003674"
     CDS             8..382
                     /locus_tag="ACGI3L_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9199353.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            379..1242
                     /locus_tag="ACGI3L_003675"
     CDS             379..1242
                     /locus_tag="ACGI3L_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199354.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            1242..1880
                     /locus_tag="ACGI3L_003676"
     CDS             1242..1880
                     /locus_tag="ACGI3L_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HFG9199355.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            2372..2785
                     /locus_tag="ACGI3L_003677"
     CDS             2372..2785
                     /locus_tag="ACGI3L_003677"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9199356.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            2976..4193
                     /locus_tag="ACGI3L_003678"
     CDS             2976..4193
                     /locus_tag="ACGI3L_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HFG9199357.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
BASE COUNT         1610 a          454 c          642 g         1521 t
ORIGIN      
        1 tgtcttattg aatatagtta ttagtaattc gagtgggaag ccaatatatg aacagattac
       61 tacacaaatt aaaagtatga ttataagtgg agagttacca gaaggctcag ctcttccaag
      121 tatgagacta ttggcaaagg aacttagaat aagtgtaatt actacaaaac gagcatatag
      181 cgatttagaa cgagacggat ttattgagac agttactggt aaaggcagtt ttgtatctag
      241 taaaaacatg gattttgtca aagaagaaca atttcgttta attgaagaat acctacaaaa
      301 agcagttgat acagcaaaaa gtagtgatat tacatatgac gaattaaaag atattttatt
      361 tttattatat aaaggagaat gataagtatg gatgcaataa ctataaaaaa tttaaataaa
      421 acttataaag attttagcct acaagatata tctttttcag taccaaaagg gagtgtaatg
      481 ggatttgtag gtgaaaatgg tgcaggaaaa acaactacat taaaagcaat tttaaattta
      541 atatcttatg atagtggaaa tatagaaatc tttggtcttg atagtaaaaa aaatgaaaaa
      601 gaaattaaag agcaaattgg ggttgtattt gagggaagca actttcatga aaatttaaac
      661 actgaccatg tttcaaaaat catgagtaaa atctataaaa attggaatga cacattattt
      721 aaagactact taaaaaaatt gagagtacca gacaataaat taattaagga gttttcaaag
      781 gggaataaga tgaaacttag tattgctgta gccttatctc ataaaccaaa attattaata
      841 ctagatgagg caactagttc acttgaccct atcgttcgtg aagaaatact agatatattt
      901 ttagatttta tacaagatga agaacactct attatcttat cttcacatat tacaagtgat
      961 ttagataaga tagcagacta tattacattt atacataaag gaaaaattgt atttagtgaa
     1021 aataaggatg aattaattga tactatggga gttttaaaat gtaaacctag tgattttgat
     1081 aacctttcaa gagaggatta ttcatattat cgtaaaagcc aatttggata tgaagtactt
     1141 cttaaagata agcatagatt tatctcaaga catccaaact gtattgttga taatacgtct
     1201 atagaagaaa ttatgttatt ttatgtgaga ggtgataaat aatgaaaggt ctaattttaa
     1261 aagatttact taatttgaaa ggaaatataa agtttatact tttattcatc attatgtttg
     1321 gctttatgtc ttctttagga gatggaaatg ttaataactt tataggtgtt attatagttt
     1381 tatgtactac aatgattgtt tcaacatttt catatgatga tttgaataaa tgggatagtt
     1441 atgtacttac aatgcctatt aatcgcaatg atattgtatt aagtaaatat ttaactatgt
     1501 taatatttag ctttataggt gttcttgttt cacttattgt tagtgtaact attggttatt
     1561 ttaaaaatac acttatatta aatgaaacac tacttattaa tgcactaatc ttatcaattt
     1621 cagtatgttt tggtagcctt attctaccac ttatttataa atttggtaca gaaagagctc
     1681 gtttattaat gattttatgc tttttagttc caacactagc tttattagtt tttaaaagta
     1741 ttttagaaaa tattagttca cctatttcta tagaaattat acttaataca ctagtatatt
     1801 ctcttccatt tgttgctatt ttactatttg tgatttcata ttttatatca tcaaaaatct
     1861 atagtaaaaa agaagtataa aatatactat atatgtttct gtatttaagt atttaaataa
     1921 aatactatcg agtttatttt ggtagtattt tattttttaa ttattaatct ctactaggta
     1981 tttattattt tattacttat atttaataag actatttact actttctaat cttatttata
     2041 taatttattc attttataaa ttgaactact aatgatatta ttgaacatag caatagaata
     2101 acatctaaaa tagtttttat gtattaaatt aacttatttt aatattcaac aatttaggtt
     2161 tactaaattt attgatgatt tctttttata taacttaaac tacattttta tttaaaaaaa
     2221 tttaatatca acaatataaa attaagaata agtattatta gtttgacatt agcataaatg
     2281 cctattagaa taatgttaaa ctatattctt tctactgatt ttattaaaaa ataccaatat
     2341 acaaaagatt atacaaggag aaagttcaaa tatggaatta gaaattacag aaaaaataga
     2401 aaaacaagat gaagatacta tttttcaagg attattaaaa tataatcttg ctagacttga
     2461 agataaaaac ccagtggatt taggaatata tattcgagat aaagcaggta aaattgttgc
     2521 aggttttata ggtgttactc atggtaattg gctttctata aaatacttat gggttagtga
     2581 gaagcttaga tataaaggta ctggaagtca acttttatat aaggctgaaa aaattgctaa
     2641 agaacgaggt tgtaaatatg tttttttaga tacattcagt tttcaagcac ctaaatttta
     2701 tgagaaattt ggataccata aagtattttc acttgaaaat tatcctctaa ctggaaagag
     2761 atattattat agaaaaatac tataataata aaaatcatat ttcatatttt taaattaaaa
     2821 cttctgctct tcgtctacag actttatgtt tttatatcat tattaatact aaaatagtat
     2881 tttactatac atacaaaatt atttgaaagt tcaaaaatta taagtataaa agctaatctt
     2941 agcttaaata aaaattatat ttttaggagg taaatatgtt aggaaaaaaa tgtatggatt
     3001 atctacaaac attaggaaaa ataagttcaa caacaaatgg tcttacaaga cttatcttga
     3061 ctcaagaaca taaaaaatct attgatttaa ttagttcatg gatggaaggt ttaaatcttg
     3121 atattgaaat tgatgacatt ggaaacgtta taggtacata taaatcaagc tttccaaatg
     3181 ctcccacatt agtagttgca tctcatcaag atagtgtaaa gtgtggaggt atatttgatg
     3241 gtatgttagg tataatagtg cctctagttg gtcttgaaga agcaaaacac aataataggt
     3301 cttatccttt caatattaag ctaattgctt tcgctgaaga ggaaggaact agatttgaaa
     3361 cttctttaat gggaagtaaa gtttttgctg gtacttttaa agaggaactt cttaaatctg
     3421 ttgatgaaaa tggaattaca cttgaagaag ctgtaacaaa gtttggattt aatacaaaaa
     3481 acttaacaaa tttgcatcct agaaaagatg tagatgcata tttagaattt catattgagc
     3541 agggtcctgt tttagaaaat gaatctcttc ctgctggaat tgtatcaagt attacaggat
     3601 ttaaaagttt taagatatca gtaaatggta agtctggaca tgctggtaca cttccaatga
     3661 atatgagact tgatgctgga tgttgtgcct gtgaatgtgt attagctatc gaaaaagtag
     3721 ctaaaacgac tactgatttg gttgctactg taggaaagat gaatttctat ccatcttcat
     3781 caaatgtggt acctgaaaga gctgaattta cactcgatgt acgctcttgt tcacaagaaa
     3841 ttcttgataa ttctgtagaa aagatattta atgaaatatc acatatatgt gaaaatagaa
     3901 aacttaatta tacaagtgaa cttgcttttg aaaatgttcc tgtaccatgt tctaataaaa
     3961 taacaaaaat catagaaaaa agttttatag atttaaatct taatcctttt tatatttata
     4021 gtggtgctgg ccatgatgct caggaaatgg ataatataac tgatattggt atggtattta
     4081 taagatgcgc tgggggcgta agtcataatc ctaatgaaag tgtctctgta gatgacttgg
     4141 atactgctgt aaaaatattt ttaaaaatac tagataatct tgatttaaaa taattcttat
     4201 ataagaaagt atattaaaat atataat
//
LOCUS       DAYAKB010000160         4103 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.164, whole genome shotgun sequence.
ACCESSION   DAYAKB010000160 DAYAKB010000000
VERSION     DAYAKB010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.164"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            179..361
                     /locus_tag="ACGI3L_003679"
     CDS             179..361
                     /locus_tag="ACGI3L_003679"
                     /inference="COORDINATES: protein motif:HMM:NF015898.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199358.1"
                     /translation="MLNKKLPDTELKIMKCIWHTGYKTVISKDVADEIEKTYGWKHTT
                     TIILLARLTKKGFLIS"
     regulatory      916..1009
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1092..1577
                     /locus_tag="ACGI3L_003680"
     CDS             1092..1577
                     /locus_tag="ACGI3L_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9199359.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     gene            1933..2331
                     /locus_tag="ACGI3L_003681"
     CDS             1933..2331
                     /locus_tag="ACGI3L_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199360.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    2767..3030
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3181..3732
                     /locus_tag="ACGI3L_003682"
     CDS             3181..3732
                     /locus_tag="ACGI3L_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HFG9199361.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1775 a          356 c          584 g         1388 t
ORIGIN      
        1 gattgtttga aagttaaata aatttataga tatgaacatt attttacact taaaaacaga
       61 ctaaacacgt agagtacctg gtaaaaatta aatatagttt ttgttctaaa aagctcctat
      121 tataatttaa gctagataaa tttgaagaag tgacataaat tgaaagaagg aatatattat
      181 gctaaataaa aaattaccag atacagaatt aaaaattatg aaatgcatat ggcatactgg
      241 ttataaaact gtaatatcaa aagatgttgc agatgaaata gaaaaaacat atggttggaa
      301 gcatacaact acaattatac ttttagctag attaaccaaa aaaggttttt taatatcata
      361 gagaattggg aggcatgtac actatacagt attaataaaa gagagagaat atctcaaaat
      421 agagggaaaa agagttttta gaggtttaca taacaatcct ttatcagaat taatttcaaa
      481 attacatgat ggagaagaaa taactgaaga aaaaataata gaaataggaa gttggataaa
      541 aagctggaaa tataaagatt aataaataaa atgtagctaa taatataagt gctacctttt
      601 ttatgtggat aatattggtg ataagttgtg gaaaacttat ataaaaattg tggataaagt
      661 gttttgctga cattttactg acaaaagtta aaaaaataaa tgttatatat tgtaaaatgt
      721 tgaaaaatag ccatatatat aaaatataag taacactata gataaattac tgtcttttat
      781 attgactata aagaacagta attgaataaa tataaagata ttttttgatt attattaatt
      841 aaaaatttaa tttatattta aataatataa aatttgaggt aatattattt tttaattgtt
      901 caaattatgt tattattcag atataggcaa tattagataa atctaatgac gcaaaactat
      961 agggactaaa atctttatgt aataaaggtc atgtcagcca gttgccaaaa agataataat
     1021 tctttttgtt aaaagtattt ttagagttat atattttaat aacttaatat ttggcaagag
     1081 gagggcttaa gatgatatct gaattaatgt taaaaaattt tcgcaaatct agcatcaatt
     1141 ttaagactaa aattaaattg aatttaagag aaaaaccaga cataaatagt ttgaaattaa
     1201 aaagtatacc agaaggtaaa attgttaagt taaagtgtgt agatggaata tgggcagaag
     1261 ttgagagtaa ttatgacaaa ggttggttac tttataaata tttagaaaga ttaagtaatg
     1321 ctaaaaacaa tagtaatgat acaataaaaa atagaaaaaa gaattacata ggaaatataa
     1381 gaacaaatgg attaagttta gaacttagaa atgatagaac attagaatct aaagttataa
     1441 ctacaatccc tgatggtttt aaagttgaag tatgttatag cgttggaaaa tgggcaagag
     1501 ttaatatcaa taaaaatgaa aaacgatatt ctggatatgt atataatcaa tacatagaag
     1561 agcatttaag tttataatac gatactagca agctttaaat atattaataa atcgcaaaaa
     1621 agaatcccat taatgggatt cttttttgta gaaacattat aacagaacta aagagaataa
     1681 attaactaat ttatttttat tataaagtaa ttataaatgg taaatttaat tgaaagtaga
     1741 tttaacttat actttataca ccaagtatca taaattaata ctactttgaa aaatcttaaa
     1801 aaaagtaaaa gttatgataa taaaaataat attaaagata ataagatata taagaaactt
     1861 gaaaaaattt gtaattttta gttatatata tattataatg aactagttaa aaatttttat
     1921 gagggggaaa atatgaataa gaagaaaaaa ttgattggga tagctatatc ttttctactt
     1981 ataatcagca ttataaatcc attacaagta gaagcagaag ctattattga gtctagtgta
     2041 tacatttctt caataaaaga gaattataca tatgataata ctaaatttaa aactattaaa
     2101 tctaaaagta gacataaaag taggaaatat aataaaagta aagtaaagtt gaaaaaacga
     2161 agtataagaa ctaaaaagta tggatatcaa actataaata aatataaaag acaaaacgca
     2221 agaagacata atatcctaac aaaattaata ttgtccataa tagtcatatt tttggttata
     2281 gttttagtag tgctaatatt tattaaaaga aagaagaaaa aattttacta aaaataatta
     2341 aaagaatatc atttttttaa tcattggtat ctatttaata atatgatgta attaaaatgg
     2401 agtaatattc tgtttcaaag gaggcatata aatacaggaa tgagtattaa atgatggtta
     2461 attaagtaaa tttattgata aatgtactta attaactttg aagaatttaa ttcctcatga
     2521 atcaaaatat aaaattacat caacagttat tcacaaaatt aatataagaa gaattagagc
     2581 caaagagcag actattagac cattaaagta attattcata gaattttgta tatgaaaaga
     2641 aatgtatagt ataatttact ttttttataa aaaatagatt acaaaatata ttttttataa
     2701 aaaggtattg acatttttta gaaaaaagaa tatcattatt ttaacaacaa aattcaatac
     2761 aataaattaa atcctatgac aaggaagagt agttaaattt aggttcagta tagagagctg
     2821 aggatggtgg aatcttagca agaaaaaatt tgatgaatgg cccttagagg aataaattga
     2881 aatcatagtt ttgagagtag actttatcgt cagtcgcacg ttatagcgaa taaggtatgt
     2941 aagtacctga taatgagatg tatgaaaatt gaattttata ttaattttta tataatttag
     3001 gtggcaacgc ggataatctc cgtcctatta gtttaggacg gagtttttta ttttactgaa
     3061 aatttaaaag atagaaggtg gtgagaaaga tgttatgaat ttcaaaagct aaagatgatg
     3121 atatagtagg ttggcaaaaa aataaattga aaattaaaaa aataggagga agtacaaaaa
     3181 atgaaaacaa atacaaaaaa attaacttta aatgcaatac ttttagcgat gggattatta
     3241 atacatcaaa tcacaccagc tataggatta ccaatgaagc cagatgtacc actagcaatg
     3301 ttatttgtaa tattggtttt aaatagagat gattataaaa cttgtttgat agcgggtata
     3361 gtaacaggaa tatttacagc acttacatca agttttccgg gaggtcaaat tcctaatgta
     3421 atagataaaa ctcttacagc aaatatagta tttttattaa tgaatattag ttataatatg
     3481 ccttttataa aaaaattagc taagaaaaca caagatactg tagtagttgc aataataatg
     3541 ccaataggaa ctcttgtaag tggaactatc tttttattag cagctcaagc tatagttggt
     3601 cttccagggg cttcatttac agctttattc ttagcagtag tattaccagc tgttttaata
     3661 aatctagttg caggaatatt tttattcaag attgttagtc tatcaataag aagagttagt
     3721 tatcaagctt aaacacgaaa taatatttta ctttataaag cattataata actaaataac
     3781 ataagaataa agtagattat aactatttta ttcttatgtt gtttaaagat ttggtattat
     3841 atatttattt ttaataaaat atttatatag taccaattac acttaattta acagataaat
     3901 tatcatacct atataatatt cttatatgta tctcatttgt agttattaaa tataagatat
     3961 atttaattga cttttcaaga taaattttta tattaatctc ctctgatttc tcattttttg
     4021 aatacactaa aatttccaat taaatcaatt atatatttat aaagttttaa aaatatagta
     4081 atgtatatat tttttgtgaa aaa
//
LOCUS       DAYAKB010000161         3925 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.165, whole genome shotgun sequence.
ACCESSION   DAYAKB010000161 DAYAKB010000000
VERSION     DAYAKB010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.165"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            463..2274
                     /locus_tag="ACGI3L_003683"
     CDS             463..2274
                     /locus_tag="ACGI3L_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9199362.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVATVLSKTFNIKETCARICSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2362..2943)
                     /locus_tag="ACGI3L_003684"
     CDS             complement(2362..2943)
                     /locus_tag="ACGI3L_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199363.1"
                     /translation="MSYLLKINQFERSYDIGIFKNEQSIYKFIEKIPFVKKDSSNFNY
                     TNYYMEFEAIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(3379..3585)
                     /locus_tag="ACGI3L_003685"
     CDS             complement(3379..3585)
                     /locus_tag="ACGI3L_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199364.1"
                     /translation="MNQSQEKDLEFIKNHWDLTIIEKERNVTRIIRYSLIILAIIAFF
                     LPTKIKFSIYIFISLFCWLMYLVL"
BASE COUNT         1508 a          383 c          524 g         1510 t
ORIGIN      
        1 tcttattgca caaaaataga tataatttaa gtaatatacc aaaaaaaagg aatatattta
       61 cataatatga taaaataaat tcaaagagtt aaattgtagg taaatagtat tttaattatt
      121 tattaaaata tagattatgt atatgccaaa tttaaaaaga gacataaaga cattatacaa
      181 atatattatt ggggtgatat tttgtaagaa aagaagtgat gcagtaaatt aattgagtaa
      241 tttaaaaatg atttaatgat aatgttgatg aatgtttaaa aagaaatttt agaaaaacgt
      301 atattgctgt ttgtgttgga ggtgatgaat ttgtagaatt tatagggtat aaatgattaa
      361 actatttaag ataaatacat atcactgtaa aatattgata atcatttttt ataagagatt
      421 gattatttgc aaattatata tattacaaat gaggtaacaa taatgaagaa aaaatatgat
      481 tttttaattt attctgctat ttggctagtt attattattc tttttatatt ttctctatat
      541 catagtatag agcatattaa aattataagt cacactggta ctattcgcag tgaaactcaa
      601 aaggttgtta agcaagaatt gaataatgaa agaaatgatg acttgataaa acgactggat
      661 aatattctga taaagctaag aacaggtaat ggagaaaatg gatttcaaag atgtgataat
      721 aaagaatttc aacaaaaact aaatcaaatg gattctatgt gggaatctat gaagaaagaa
      781 attataaaag ttagaaatgg tgcttcaggt gataaattat ataaattgag tgaagagtat
      841 tctgtgttgt ctaatcaaat tgtttttata tctgaaaaac actctaatgc aaaattgtat
      901 tcttttgcta ctgcactatt tatttatctt atattctcaa caataagtct tttaatttgg
      961 gaatattata ataaaaaaag gtttaaaaga atattttata ctgataattt aacaaaaata
     1021 aaaaatcagg ttgcatttga aaacagagcg attgaaattt tgcacaatgc atctaacaaa
     1081 gagtatgtac tgctaaatat tgatattgac aattttaaat atattaatga tacacatgga
     1141 tatgaatatg gagataaagt tctaataata gttgcaactg ttctttctaa aacttttaat
     1201 ataaaagaaa cttgtgcaag aatttgttca gataattttg taatacttgc aaaatataga
     1261 gattctcttt tagaggatat tcgggaaatg ctaactaatg ctataatctc tgaattagat
     1321 atgaatgtaa ctcaaactat atcttattgt ataggagctt acttagttga aattgataat
     1381 ttaggttata aatctatcaa ttctatgatg gataaggcaa atattgcaca caaggtaagt
     1441 aaaacaagag gaatttcctc cacagtatgg tataatgaaa atctgttaaa acagttacaa
     1501 atggaaaata gtatttataa ttatatgtat aaagcgatag aaaatgaaga atttcatatg
     1561 tatttgcaac ctaaatttca aatatcttct ttaaatgttg tgagcgcaga agctcttgta
     1621 agatggtttt ctccagaact tggtttttta tcaccagatg aatttattcc attgtttgaa
     1681 aaaagtggat ttattattga attggacttt tatatgttaa aaaaagcgtg ttcatttgta
     1741 aaaaaaacgt ttatgaaaaa aaatcaatat acatatccga ttgcagttaa tttttcaagg
     1801 gttactattt accaaaatag tttttatcaa aggtttttag atactgttaa agaatatgaa
     1861 attcctttta agtatataga gatagaggta actgaaagtg cttttaatga aatatctcaa
     1921 ccagttattt caattttaga ggaacttaaa aagttaggat ttttaatttc tatggatgat
     1981 tttggatcag gatactcttc attaagtctt ttatgttctc tatctattaa tggattgaag
     2041 ttagataaaa gcttacttaa agaaacattt aaccgggaga aagtatatag tattattcag
     2101 tgtattattg aaatgtcaca tcgtataggc atgtctgttg tatgtgaagg tattgaaact
     2161 aaaaaagact tggaattttt aaatacagtt aaatgtgatg taggacaagg gttttatttt
     2221 tctaaaccga tagaagaaaa agaatttttt aacaaatatg taactaaaaa ataatataat
     2281 tatttttatc agtctataca ttgagtcatt ttatatctcg ttaaatgact caatgcactg
     2341 ttatgtattt taaaatataa attatttaaa acgtttttta tacttatata gaaattcttc
     2401 tatatttttt gattgttctc ttatttcaac tgcttctata tctagtaaat aaagtataga
     2461 atcatttgta agttcaacat attcaccatc ttctgaaccg agtgcatgtc tctcaatttt
     2521 taatcctttt tcttcataat atttttttgt ttctatatat aatgattctc gcttttgtat
     2581 gtagtctttc acttcattat ttggaaagtt atatgaatcc actaatgttt cgccatttat
     2641 aaaagttttc tcggtagcaa ctttttcatc ccaacaatgg atttcttccc aagtaaaaaa
     2701 tatctcagtt ccatctggaa tgaatgaaaa cctggtaata atatataaat aattattgaa
     2761 atttacttca taatattcag gaatagcttc aaattccata tagtaatttg tataattaaa
     2821 gttactacta tcttttttta caaatggtat tttctcaata aatttatata ttgattgttc
     2881 atttttaaaa attcctatat catagcttct ttcaaattga ttaattttta ataaatatga
     2941 catatattct ccttatttgt tgaaatataa tttttataac tctactaatt ttaaacattt
     3001 ttaaataaat atttgtatat accttatata atattatagt aattagtttt aaatcaatag
     3061 aatagtatgt atttatctaa tgcggcaata taatttaaag ctggtgttgt agaaaaacta
     3121 agagtgaata tagcaaagag aagcaatagt attttaaact ttgtctctct tattttttga
     3181 aaactaacat taaaacataa ggtataaata atattatcat ataaatgaaa acaaatttga
     3241 atttttctct ggtcgatgta tatagtaagt ttgttgatat gagaaaaatt attattgata
     3301 atatacatgc atagaaagga aatggtatat aatattttct taagtttctt ttttaggcat
     3361 ttctattggc attttaggct atagtactaa atacattaac caacaaaata atgaaataaa
     3421 tatatatata gaaaacttaa ttttcgtggg aagaaaaaaa gcaataatag caagtattat
     3481 tagagaataa cgaataatac gagtaacatt tctttctttt tctatgatag ttaaatccca
     3541 gtgatttttt ataaattcaa ggtctttttc ttgactctga ttcatttaat catctcctgt
     3601 taatagtata attttaaagc tattactttg ttttatttta acatatttat acactaaagt
     3661 gaattttatg attagattta tttaattatt tctgaattaa aacttattag aattctctat
     3721 tttgataatt tcaaactcta ttgattgtat gataattgaa actataggat atgtaggata
     3781 acaagtttca aagtagttaa aataaaaaag ataatgatat tattaattta gaataaattt
     3841 tatatattat atttaattat ttacttgttt taagttttat taacttaaaa aatgtaagaa
     3901 atttattatc aataatctaa atata
//
LOCUS       DAYAKB010000162         3884 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.166, whole genome shotgun sequence.
ACCESSION   DAYAKB010000162 DAYAKB010000000
VERSION     DAYAKB010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3884
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.166"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(105..323)
                     /locus_tag="ACGI3L_003686"
     CDS             complement(105..323)
                     /locus_tag="ACGI3L_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9199365.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(324..731)
                     /locus_tag="ACGI3L_003687"
     CDS             complement(324..731)
                     /locus_tag="ACGI3L_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199366.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(817..1305)
                     /locus_tag="ACGI3L_003688"
     CDS             complement(817..1305)
                     /locus_tag="ACGI3L_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HFG9199367.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(1510..2607)
                     /locus_tag="ACGI3L_003689"
     CDS             complement(1510..2607)
                     /locus_tag="ACGI3L_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFG9199368.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIAKGKREEKFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            complement(2980..3150)
                     /locus_tag="ACGI3L_003690"
     CDS             complement(2980..3150)
                     /locus_tag="ACGI3L_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199369.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(3322..3765)
                     /locus_tag="ACGI3L_003691"
     CDS             complement(3322..3765)
                     /locus_tag="ACGI3L_003691"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9199370.1"
                     /translation="MIEIKTIEINKKSRIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1328 a          637 c          352 g         1567 t
ORIGIN      
        1 atgagcttgg tttttcatct ataagtcatt tattctctaa tctataagct tggtttttta
       61 cctataatta attcattctc taatgcataa gtaatacatg aaatttaaat attattttct
      121 tcaataaatt caaacaactc ttctacagtt gtatcaaata ccttagcaat atccattgcc
      181 agttttaaag aaggattgta gcgaccattt tctaaatgta caatagtttc acgtcttact
      241 cctactgact ttgcaagttc accttgtgtc ataaggttct tttctctata ggatttaatt
      301 tttgtcttta gtaatactga cacctaattg tatatcccct ttctgtcaaa atatataaat
      361 agaattaact tcaacaagga ttgaataaac aaaatgacta ataaagacat tcctatattt
      421 aaatttgaca catttatgtc caaagttaca agaaatatag atactatagc tacagaaaaa
      481 aacaatactt ttattgcaat atcattaact cttgatagta tacattttga tgcctcatca
      541 attaaatcat catacttttt attatagacc cactgagctc ccatagctaa tacccaaata
      601 attataggaa gatattcaat actacttcct ttaaaaaaat acttatttac taatgtagct
      661 ccaatacaat aagaaattcc caatatttct gaaataagtg ttgatttaat accagtttgt
      721 tgtttagaca tataaaatcc cccttaaaaa gttatgtatt tataacacct cttgttataa
      781 atatataact tttttgaata aatttcaata aaaatattat tttgcaacaa attcttttat
      841 taattttaca ttagatagag gcactttaga tgtcactcct tgcaatgtca aatcttctat
      901 attaacttca tttaattttg aacacagttc taagtcaaat attctttccc agcttacctt
      961 cttttcaatt tgttcatctt cataaagctc tacagtaata tccattaaag gtaaatgcca
     1021 taaatcaaat tctgataata acacattgtc ttcacttatt tctatttcaa gtaaaacacc
     1081 tttttttcct ttttctaaat aaccactaca tcttaaatca ggtctcttcg tccaaaccca
     1141 tatcatacta tcatcaaatt catatattct atttgtcatt tgactataca tccatttgta
     1201 tggaatatca aagtcttcta atataaaaga ataatcattt gatagatatt tattgttttt
     1261 attgttattc caaaattcta aagtctgtat agtataaaat ttcatatata aatcaacccc
     1321 tttgtttttc tataagaagg agatggttca aacttttatt ttgaattatc tcctttattt
     1381 atacacctct ttgtacctat tatttatata tctctttata tctaccatat ttaaataaca
     1441 aagttttata ttaatttaaa tttaaaagag gaagctttgt atttatctag tgccatctca
     1501 atcatagtat tagttttgat tatagacttt ttcaacctct gatttattca aatcatctat
     1561 aatatcgcat atttcactca aattgtatcc tttatttttt aattttatga tgatattaaa
     1621 tttctcttct cttttccctt ttgcaatacc tttttcaata ccttcttgaa aaatttcttc
     1681 tttaaaattt ctacttttat tcataatata cgcacctctc tttaaattta ataaatagtc
     1741 ctcattacta cctaattctt ttaatctatc aagtgctctt ttaataacat aatccgtttt
     1801 agatagtatt ctaatatcta tatgagaagg attatcaata agtttacccc atattagaac
     1861 tctgtttgct atacaactgg atttacgaat ttttggaagt tctataaaat ataatgcagt
     1921 tttactagaa taaatatctg gatgcccgtc cattgttaat ctcaggcaat ttacataatc
     1981 ttctatgtga ttatatttta catgatttag tatatgtatt ccaacagttt ttccaatttc
     2041 tttatattct ttaccttctt ctaactttct accatgtaca cgactaagat aatattcagc
     2101 tctttccaaa taatcctctt caagagctct ttgcatctca atatttatat ggttacgttc
     2161 ttcatcttca gccaaaatat caagtctagg tcttttctca ccaatgtaat taattgttgg
     2221 gtcggtttca accttaatta ttctttttat ttgagtgaac tgtttgatat tcctattagc
     2281 atatggagca tctttgagga tatcatttat aaaatttgca agtaaatcgt aatcattatt
     2341 taaagtaaac aatgatttaa atacctcatc atactcaggc ttagcatacc catcttcagt
     2401 tacaacttct ccaacatttt cactagtcaa tatttctttt ggaattaaat ccttgatttt
     2461 atctaatttt tcattagaaa aatcacctct actaagtatg tcatttaatt ttttggtcca
     2521 ttctctgtcc ttttcttcaa ttatagttcg tttatactct tttgatgttt taataatctt
     2581 agatttttct tctaattttt ctttcatatc aacacctctt ttttattatt acccatttct
     2641 tcataccaaa gtctgaactt ctaagtaaaa tttgcattat tgaaataaga accttataaa
     2701 cttatatatc attactaaag ttaagacttt aaagagaagc acttagatta caatagattt
     2761 tagatagctt tctttttaaa actattgttg ataaatgaat gaatataagg gtatgtatta
     2821 aaatagagat actcatcttt ttcattgttt aaataatgaa aatatatttt atttaataca
     2881 aaaaagagtg ccttataaac taaaagttca cttcgagaca ctcccttaca ttttgtttct
     2941 taaactttac aatattacat acttatttat taatttaatc tatgcatact taacccaata
     3001 ataaagtaca tatatccaac tcattaagcc atgaaaaata gcccatggaa tagatttcca
     3061 tgcagtataa gaaataatca ttgctaaaca agaaccaaaa gaaataccct ttttaacagt
     3121 tgattttata gtattattat ttgaatccat aattaatcct ccaaaattca aaataaacaa
     3181 gttattatat atcttatttg aatataatac aatataacag cttctaaata aattatactc
     3241 ttattataca taatttataa attataattc cgataattat atgaattaat taattatatt
     3301 aacctaaaaa tattatccta tctaaaagtt atatgataga tacaacatgt caacacattg
     3361 taattctcct tcaaagattg gttctggata attatctaca aaaaagtttt taattttatg
     3421 tgaataaaca aatccaaact tctcataaaa aggaactccg ctttcagatg taccaacaac
     3481 cattgatgaa tattttttac tataaacatc taaaagatga taaatcatct ttgaggcata
     3541 acccatattt tgaaaatgct catatgtagc aatgtttttt aattcacata tttctttgga
     3601 aatttcattt acaactgcta tacaagtaag ttctttatta tcatacaatg cgtacatagt
     3661 tcctttattg agatatttat caatcatttc ttcacatggg tcggctaaca ttaaaaggtc
     3721 aattcgactt tttttattta tttctatagt ttttatttct atcataagtt ctccaccctc
     3781 actttattca aaccttaatt taacaaactt cttacagtac ttatttaatt cattttgata
     3841 tatattttta ctttttaaaa tatagtgata attccctaga atat
//
LOCUS       DAYAKB010000163         3882 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.167, whole genome shotgun sequence.
ACCESSION   DAYAKB010000163 DAYAKB010000000
VERSION     DAYAKB010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3882
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.167"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            885..1547
                     /locus_tag="ACGI3L_003692"
     CDS             885..1547
                     /locus_tag="ACGI3L_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199371.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1556..>3882
                     /locus_tag="ACGI3L_003693"
     CDS             1556..>3882
                     /locus_tag="ACGI3L_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9199372.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIP"
BASE COUNT         1734 a          346 c          583 g         1219 t
ORIGIN      
        1 tgctaaaatt taattgaata aattaaaaat ataatgaaag tttagtttta attcatttat
       61 ttaataaaca tttcaagtaa aataatgttt aaatcagaaa tataaataaa tattattata
      121 atcgttatta aagaccaaaa atcccacctt agaagtttgt atcatatgaa acctttatag
      181 attatgaaag caataatata gtgtatgata tataaaataa gttataaaag tattttttta
      241 gatattcaaa aagacattgt aagttatatt aataatatgg gtatcaacga attttggata
      301 taatgagttt ttcaacttaa agttatgtaa taatgaatgt aaagaatatt taatgaaatc
      361 attttgttgg ttatgtctag ctgaatacaa taatctttta gataaagatt ttatatttga
      421 agataggtgt gaaaaaatta agaagatatt aacatcagca gtttagaggc aaagcatgta
      481 aagtaaagtc tgggtaacta aaagtagtaa tttagattgt aactattgtt ataaatatga
      541 aaatgaggaa acaggaaata taagttagga tgtagaaaat aggttactaa ataaaaagct
      601 taattatata atcaaagaaa taggtatata ctgtacaatt tcatggtgaa gaacttttcc
      661 taaataaaaa ggttggtaaa agagatataa gaaataaaat tcaattataa gatatggtat
      721 gataactaaa ggcactatat ggagtgaata ggcggaagaa ttttttgaaa attataaaaa
      781 tagtttctgt tgctacatat caataagtat agatagagat tgcaaaatcc atagcaaaaa
      841 tcgaatttat aagtgtaaat aacatgtaag acaaggagta aattatgagt attttagaga
      901 taaaaaacct aaataaaata tatggtaaat cggaaacaga ggtgaaagcg ttaagtcaaa
      961 taaatctaaa aataaatagt ggagaatttg ttgtgatagt aggtaaaagt ggaagtggga
     1021 aaagtacttt actacacata atggcaggac ttgaaactcc aacaaatggt gatgtgatta
     1081 ttgataatat aaatatatca tctcttgatg aaaagaaaag atctgcatta cgtaaagaaa
     1141 agttgggatt aatatttcaa tcatataatt tgattccagt tttaactgtt gaagaaaata
     1201 taaaactacc aactataaat ataaaaaata aagatgaagc ttatattaat gaattgatgg
     1261 agttactagg aataaaagat agaagaatgt atttgccaaa tcaattatca ggtgggcaac
     1321 aacaaagagt agcaatagca agggctcttg taaataaacc atcaattgta tttgctgatg
     1381 aacctactgg aaatttagac acaaagacag agtcagatgt attaagttta ttaaaagaat
     1441 ctcaaaaaaa atataatcag acaataataa tgataacaca taatatagat ataacaaaat
     1501 atgctgatag agttatagaa atagaagatg gatttataag agagtaggta gatttatgaa
     1561 acttaattat attgtaaaaa aatatataat gggaaataag aaaaatacat tattaataat
     1621 tgtaagtatt gtaatttcaa cagcgttgtt tttaattatg aatataataa gtgaagatgc
     1681 gacaaactta atgataaatc aagctaaaaa tgaatttaca ttaaaacatg cacaatatat
     1741 caatccaaaa gacgaagaaa taaaatatat agaaaataac acaagtatag ataaagttgg
     1801 aaaatcaatg cttttaggaa ttagtgatat tggtaaaggt caaacactac aaattctatc
     1861 tcaggataaa gttgctgaag aactaaatga tatttacaca ctagaaaaag gtaaattacc
     1921 agtagctgaa aatgaaatcg ctatagattc atggtatatt aaacaaaaaa agataaaaaa
     1981 ccctatagga aaaaggataa cattagatta tagaagacaa gggatagatc aagaagattt
     2041 atatactggg gaaaaagaat ttaaaataac tggtatctta aatagtaatc ctattttaaa
     2101 agctcaagga acatcaattg gccttataag taacgattgt gctatcaaga atattcctac
     2161 taaaaataaa tatgatcaag ttatgtttac ttttaaaaag gaaaaaaata tacagagaca
     2221 atcacaaaaa cttattaaaa atggaaattt gaatgagaat aacatttatt ttaataatga
     2281 attattaata gctatatctg atagtatgaa tttaaaaata ccttatataa tagttaatat
     2341 agtactagca ctagcaacta tattattaat ttataatatt ttttatatat tagtatcaaa
     2401 tagaataaag gattttggga tatttagggc tttagggttt aatccaaatg atatttttaa
     2461 aataatgatt ttagaagtat ctatatactc tattataagt atttctatag gtctaatttt
     2521 aggtgggata atagctagtt tatcaaggga gtatgttata ggagtaatat acaatgtcaa
     2581 ctatataaat tctataaaaa accagaacta tataaacaca tacataattt ctatattatt
     2641 aagtttagga actataataa tatcagtttc aaaacctctt atgttatcag ttaaaactga
     2701 tccaatgatt tgtataagaa gaaataatga aaaagtggat ataaaacaaa attcctttat
     2761 aaataaattt atgataaaac ttttcaaaga ctatggtaac atagcatcaa aaaatataca
     2821 aagaaataag aaacgtacaa atttatctat agcatcaatg gtaattatat ttttcttaat
     2881 ggcaacaata tacacaaagt ctactagtaa ctttttaagt gatggtgtat taaaatattg
     2941 gatacaagga gattatttat tacataatat tgatataagt actatacgtt caaataataa
     3001 aggttatgat aaaaatgtac tacaagagat aaaggcaatt gatggtgtaa caaaagtaaa
     3061 ctcatatagg cataagtggt ttaatataaa aattgatgat aaaagtataa ataagaactc
     3121 tgattattgg aaaaaaaata aagataatat tgaagctaga tcagaagtaa aagatggaat
     3181 taaggtatat aataattctt ttgaattttt aggaatagaa gatacagata tactagagga
     3241 tttcttgata aatggaaagg aaaatataga taaatttagt aaacaaccat atctgtatat
     3301 aacaaagaaa tccagtgatt cgcttaatat aaaaaaagga gatagaataa aagtatactt
     3361 tgatattata gattcaaaaa caaataattt taccaaaaca atatctcaag aatttatagt
     3421 atgtggaatt ataactacat taccagtaac ctcacaagtg ggagctgaat ttggcggagt
     3481 aatatcaaca aatcaattta ataagtttac aggaatatca tcttatgaaa gatttgacat
     3541 atggacgagt aaactagcca atgataaata tgttgaaagt gagttaaaca aaataacaga
     3601 aaaaacaaat aaaggaattt taattccata caaagctgaa acagctgaat atgaaaaaat
     3661 tgataatcaa aaaacactaa ttatggtatt agtaactgga attatagtta tattatcttt
     3721 atttaattgt tgcaatacta tagttactag tattaatagc agaagtaggg aatttgcact
     3781 atttagagga ataggaatat caaaacatga aataaataaa attgttaaat tggaaagtta
     3841 tatatatatt atagtaagct tttgtatatc tataatacct at
//
LOCUS       DAYAKB010000164         3804 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.168, whole genome shotgun sequence.
ACCESSION   DAYAKB010000164 DAYAKB010000000
VERSION     DAYAKB010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.168"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..303
                     /locus_tag="ACGI3L_003694"
     CDS             <1..303
                     /locus_tag="ACGI3L_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199373.1"
                     /translation="NSNILKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKR
                     LIDEDLYLIAKSKEVFDFFNLDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            340..2934
                     /gene="clpB"
                     /locus_tag="ACGI3L_003695"
     CDS             340..2934
                     /gene="clpB"
                     /locus_tag="ACGI3L_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFG9199374.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNNFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAYEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(3130..>3804)
                     /locus_tag="ACGI3L_003696"
     CDS             complement(3130..>3804)
                     /locus_tag="ACGI3L_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9199375.1"
                     /translation="KHPQPLLDLEIFRNFKFSLNLICALTSFICIASSSILIPFYLQS
                     TMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKIILIGLLVMSFGFFLMSRLK
                     ESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKLGVVGSINSLVRNLGQVIGI
                     TISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYIIVTLVCLIGAILIGFYLFK
                     YNKNEQ"
BASE COUNT         1593 a          401 c          661 g         1149 t
ORIGIN      
        1 aattcaaaca tattaaaagt gtttaataat attgctattt atcaatataa tattttagaa
       61 aatctataca ctattgattt taaaaagagt tttatagata aatgtcagta tttattaata
      121 ggtgaaaaaa gacttataga tgaagacttg tatttaatag caaaatcaaa agaagtattc
      181 gattttttta atttagatgg aacatttaat ttaacattga gtttcgatat acaaaaaaac
      241 gagaatttac ttgatagtct tttagagctt agaaaatcaa taattataaa tgagagaatt
      301 taatttattt ggatataata ttaaaatgga gggatttata tggacgtaga aaaaatgact
      361 ttaagagttc aaaaaagttt aaatgaggct tataacgaag cagtaaaaaa tcataaccaa
      421 caagtagatg taattcatct tttctcagca cttattaatc aagaggatgg attgatacca
      481 aatataatcg aaaaaatgaa tatatcaatt gattctttga gaaatactgt aaactttgaa
      541 attgataagc ttccaaaggt atatggagaa ggtgctgact cacaaggagt atcagctact
      601 agaaaaataa atgaggtgct tataaaggca gagagtattt ctaaagaatt taaagattca
      661 tatataagtg tagagcatgt tatgcttgca atgatggaaa cagaatcaaa atcagctgtt
      721 ggtaaaatat taaaacaata taatataaat aagaataact ttttaaatat tttatcacaa
      781 gtgagaggta gtcaaagagt agaaacacaa gacccagaag gcacatatga tgcacttgct
      841 agatatggaa caaatttagt agatttagcc aagaaaaata aattagaccc tgtaattggg
      901 agagatgaag aaataagaag gattataaga attttatcaa gaagaacaaa aaataatcct
      961 gtattgattg gtgagccagg tgtaggtaaa actgcaattg tagaagggtt agcagagaga
     1021 atagtaagag gagatgtccc agaaggttta aaagataaga ttgtattctc acttgatatg
     1081 ggagctttaa ttgctggtgc aaaatataga ggtgaatttg aagaaagatt aaaggcagtt
     1141 ttaaaagaag ttcaaagttc tgatggaaaa attatactgt ttatagatga gattcatact
     1201 attgttggag ctggtaaaac agaaggttca atggatgcag gtaatcttat taaacctatg
     1261 cttgcaagag gtgaattgaa ctgtattggt gcaactactt ttgatgaata tagaaagtat
     1321 atagaaaaag ataaggctct tgaaagacgt tttcagcctg taattgcaga agaacctact
     1381 gttgaagata caatatctat acttagaggt ttaaaagaaa gatttgagat acatcatgga
     1441 gtaagaatac atgataatgc tattgtagca gcagcaaaac tttctcatag atatatacaa
     1501 gatagatttt taccagataa agcaattgat ttaattgatg aagctggagc tatgattcgt
     1561 agtgaaatag attcattgcc aacagaatta gatgttgtta gaagaaagtt atttacatta
     1621 gaaactgaaa gagaagcatt acttaaagaa aatgatgata aaagtaaatc aagattggat
     1681 gatattcaaa aagaaatagc agagttaaaa tctaaaaatg atgaaatgac agcaaaatat
     1741 gaaaaagaaa agagtcaaat attagatatt aaaaacttaa aggctcaatt agacgaagct
     1801 aaaggtaaag ctgaaaagta tgaaagagaa tatgatttca acaaagcagc agaggttaaa
     1861 tatggtgaaa tacctaagtt agaagaacaa ataaagcagt acgaagaaaa tatgaatgat
     1921 ggttctgaaa attctctttt aaaagaagaa gttactgaag aagaaatatc tagcattgta
     1981 tcaaagtgga caggtatacc agtaactaaa ctagttgaag gagaaagaga aaaattactt
     2041 aaactagaag atgaacttca taaaagagtt attggacaag atgaagcagt tacagcagtt
     2101 tcaaatgcag taatacgtgc aagagcagga ttaaaagatg aaagaaaacc aattggttca
     2161 tttattttct taggccctac aggtgttggt aaaactgaac ttgcaaaaac tcttgctaga
     2221 aatttattcg atagtgaaga taatataata agaatagata tgtctgaata catggaaaaa
     2281 catgctgtat caagactagt tggacctcct ccagggtacg tgggatatga agagggtggt
     2341 caacttacag aagcagttag acgtgctcct tattctgtaa tactatttga tgagatagaa
     2401 aaagcatatg aggatgtatt taacatgttc ttacagatat tagatgatgg tagacttact
     2461 gataataaag gtaagacagt agactttaaa aatactctta taataatgac ttctaatata
     2521 ggaagtaatt atctattaga agcaggagga aatataacag agactactaa caatttagta
     2581 atgaatgaaa tgaagcatag atttaaacct gagtttttaa acagagtaga tgatattata
     2641 atgtttaagc ctttagacca agaaaatatc aagaaaatta tagatatatt tatgaaagat
     2701 ttaaaaaata gattaaaaga aaaagatatt actattgaag ttacaaattc agcaaaagat
     2761 gttatggtga gagaaggata tgaccctgta tatggagcaa gacctcttaa gagatatata
     2821 ggaaatacat tagaaactat aattgcaaag aaacttattg ctggagatgt gtataatgga
     2881 tgtactatag ttatagatgg aaaagatgaa aatattgaag ttttagttaa ataataaaag
     2941 aatcagttga gcataatata ctaaatattt tgctcagctg atttttattt ataaactata
     3001 ggaaaagaaa tattttatca aattaataaa acatttttaa gtcaatatgt ccaaattaaa
     3061 tttaactcaa aggaagtatt ttagtaaatt tcttataata taatcataat ttgaatataa
     3121 ttataaaaac tattgttcat ttttattata tttaaataaa taaaagccaa ttaatattgc
     3181 acctattaag caaacaagtg taacaataat ataaacattt ctcattccaa atacaaatat
     3241 tttatcatta ttaatcacat aatcattgac cctatatcca gctttaatac tcataaaatt
     3301 atataaaagt gttgtagaaa tagtaatacc tataacttgt cctaaatttc ttacaaggga
     3361 atttatgctt cctacaactc ctagcttact tctagaacag cttgacatta tcaaagcatt
     3421 gttagcaggt tgaaatatag cttgtcctat tgatattatc gatatataaa ttacaaataa
     3481 aataagggca gaactttctt tcaatcttga cattagaaag aatccaaaac tcataacgag
     3541 aagaccaatt aaaataattt tttctgactt aattttatct gatatattcc caaatatagg
     3601 tgaaaaaatg gctaaaatca aaggtgatag tatcataaat aaacctgctt gaataggggg
     3661 aagtttcata gtactttgta aataaaatgg aattaaaata cttgatgatg caatacaaat
     3721 gaatgatgta agagcacaaa ttaaattcaa tgaaaattta aaatttctaa aaatttcaag
     3781 gtcaagaagc ggttgaggat gttt
//
LOCUS       DAYAKB010000165         3719 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.170, whole genome shotgun sequence.
ACCESSION   DAYAKB010000165 DAYAKB010000000
VERSION     DAYAKB010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.170"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(43..582)
                     /locus_tag="ACGI3L_003697"
     CDS             complement(43..582)
                     /locus_tag="ACGI3L_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199376.1"
                     /translation="MLNEDVVKKLKNVPSDTNSEIGKVNTNIETAKTELNTKIDQLIA
                     GGSNVASTQTITIDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENVVTNFKIID
                     DNSIEIRSETRSELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFVNLEEK
                     VNGGLSNIATSVNELITYC"
     gene            complement(662..985)
                     /locus_tag="ACGI3L_003698"
     CDS             complement(662..985)
                     /locus_tag="ACGI3L_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1375 family protein"
                     /protein_id="HFG9199377.1"
                     /translation="MLNINEEKIEKLKQKQKINNLDTSQKTQDNDITDLMLATAEICE
                     MILSSQQTSTMSLKNIKLNEGGSSMAAIYVGLIERGLKTIDQVPVKYREEVRKMCEAL
                     EISLS"
     gene            complement(997..>3719)
                     /locus_tag="ACGI3L_003699"
     CDS             complement(997..>3719)
                     /locus_tag="ACGI3L_003699"
                     /inference="COORDINATES: protein motif:HMM:NF012632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199378.1"
                     /translation="FDKLIFTKINIENIKNGISSGDSTFLLKNDGTLYSCGMNTSGQL
                     GLGDTTNRNVFTKVNIELKNNFTEYANNYKIVLGDTSFILKNDNTLWGSGSSSYGQLG
                     LGDTAGKRVFTRMNVENIKDVVCGKMHVVVLKNDGTVWNSGNNSNGQLGLGDTTNRNV
                     FTKVDIDNVKKVICGWNQTVILKNDNTVWSTGLNSNGQLGLGDTTNRNVFTKVDIDNV
                     KEIICGNNQTFIQKEDGSIWSTGNNSYGELGLGDIAQRNIFTKVDIDNVKKIACGQAY
                     TFIIKNDGTLYSCGFNYSGQLGLGDTTNRNVFTKVNIDNVKEVICASNHTFILKEDGS
                     IWSTGNNSYSQLCLGDNTQRTTFTKVDIDNIKEIACSDSVTFVIKNDGAIFSVGYNGY
                     GQLGLGVSDGSVNEITKIEGHYLYRFDTLNNYILNNNFNLINNKYIIPSRSDINYKSV
                     LGSVYKENYDIDNDRIELQDNIKEFWMSKTHSLIVNTSGELFGCGENIYGQLLNPRTT
                     TSLTSFTKLNFADIRQASCGVGFSYFLKNDGTLYSTGLNSEYQLGLGHNNEVNGLQRV
                     NISNVKKVMCDDKFTLVLLNDNSVWGQGLNRFSNFGLGEASANTIIKTFTKLDVDVED
                     VEIGGDYISFRKLDKSLWICGKIRDCYNMKSNNPYIFNKVQIPEEFNNDLVYLDAGRD
                     ETLFMNYQVPTTKPSIELAEKTIAGIKLKVNDSNNEIDKIEMYLNNELIHSKNEFINN
                     FVLFTIPLEKLNLGINNIYFKANTLFGDNMYLGATINKENNSINISEGANLFIKNKKY
                     NINSLTNSADGKLVITLDRALEDNISVGDIIYQLINQLKVQVKTNNTGMHKDMNLLEM
                     KKVDTGYQEIYELEEKGMTQAEPKIIVEKGDNWTAIKRPSMIFSIDETTL"
BASE COUNT         1175 a          673 c          335 g         1536 t
ORIGIN      
        1 taaccaaaat tccattcagt ctgcattttc tcactctcct ctctaacaat aagttattaa
       61 ctcatttaca ctagttgcaa tattagataa accaccattt accttttctt ctagattaac
      121 aaatctatct tcgattttct tagacgaata agtagtcatt tcagatactc tgttatcatc
      181 tacagttgca ttaataaaat gagtttctgc atttccattt atcacataaa cgtttaattc
      241 tgaccttgtt tcacttctaa tttctataga attatcatct ataattttaa aatttgtaac
      301 tacattttct tttgtagtag catctataat atttacaact attctctgtg ttaataaact
      361 atgtgttaca gttgctttga atccattttc tgcatcctca acccaatcgt caattgttat
      421 tgtttgagta gatgccacat tagagccacc cgctataagt tggtcgattt tagtatttaa
      481 ctctgtttta gcagtttcta tatttgtatt aacttttcca atttcactat tagtgtcact
      541 aggtacattc tttaattttt ttactacgtc ttcatttaac aatttatcac cttctttttt
      601 atttagagag ctacattagt aactctctat tttgaacata aaaaaaagaa ctcttatagt
      661 tctatgataa tgaaatctct agtgcttcac acatttttct tacctcttct ctatatttca
      721 caggtacttg gtcaattgtt tttaaacctc tttctattaa tcctacataa attgctgcca
      781 tactacttcc tccttcattt aattttatat tttttaatga catagtagat gtctgttgac
      841 tacttaatat catttcacat atttcagcag tcgctaacat taaatctgtt atgtcattat
      901 cttgcgtttt ttgacttgta tccaaattat ttattttttg tttttgtttg agtttttcaa
      961 ttttttcttc atttatattt aacatttaat cacctcttaa agcgtagtct catctataga
     1021 aaatatcata gatggtcttt ttattgcagt ccaattatca cctttttcaa ctatgatttt
     1081 aggctctgct tgtgtcattc ctttttcttc caactcataa atttcttgat atcctgtatc
     1141 aacttttttc atttctaata aattcatatc tttatgcata cctgtgttat ttgttttaac
     1201 ttgaaccttt agttgattta taagttgata aattatatct cctacgctta tattatcttc
     1261 taatgctcta tctaatgtta ttacaagctt accatctgca ctatttgtta aagaatttat
     1321 gttatacttt ttattcttaa taaatagatt agccccttct gaaatattta tagaattatt
     1381 ctctttatta attgttgctc ctagatacat attatctcca aataaagtat tagctttaaa
     1441 gtatatatta tttataccaa gattcaattt ttcaagcgga atagtgaaca gcacaaaatt
     1501 attgataaat tcattctttg aatgtattaa ttcattgttt aaatacattt caattttatc
     1561 aatttcatta tttgaatcat taacttttaa ttttatacca gctatagttt tttcagctaa
     1621 ttctatagat ggttttgttg taggtacttg gtaattcata aataaagttt catctcttcc
     1681 agcatctaaa taaactaaat cattattaaa ttcttctggt atttgaactt tattaaatat
     1741 atatggatta ttagatttca tattataaca atctcttatt ttgccacata tccataaaga
     1801 tttatctaac tttctaaaag atatataatc tccacctatc tctacatctt ctacatctac
     1861 atctagttta gtaaatgttt ttattatagt atttgcagaa gcttcaccta atccaaaatt
     1921 actaaatcta ttcaatcctt gaccccatac agaattatca tttaataata ctaaagtaaa
     1981 cttatcatca cacattactt tctttacatt agatatattt actctttgta atccatttac
     2041 ctcattatta tgacctagcc ctagttggta ttctgaattt aatcctgttg aatacaaagt
     2101 accatcattt ttcagaaaat atgagaatcc aacgccacat gaagcttgtc ttatatctgc
     2161 aaaatttagt ttagtaaagc ttgtcaacga agttgttgtt cttggattta ataattgacc
     2221 atatatattc tctccacatc caaataactc tccacttgta tttacaatca atgaatgagt
     2281 ctttgacatc caaaattctt ttatgttatc ttgtaattct attctatcat tatctatatc
     2341 ataattttct ttatatacag agcctaaaac gcttttataa tttatatcac ttcgtgatgg
     2401 tattatatat ttgttattta tcagattaaa attattgttt aatatataat tattcaaagt
     2461 gtcaaatcta taaaggtaat gtccttctat tttagtaatt tcatttacag aaccatcact
     2521 tactcctaaa ccaagttgcc cataaccatt atatcctaca ctgaaaatag caccatcatt
     2581 tttaattaca aaagtaacag aatcgctaca agcaatttct tttatattat ctatatcaac
     2641 ttttgtaaat gtagttctct gtgtattatc acctaaacaa agttgactat aagaattatt
     2701 tcctgtactc caaatactcc catcttcttt taatataaat gtatgattac tagcacatat
     2761 gacttcttta acattatcta tattaacttt agtaaataca tttctattag tagtatcacc
     2821 taaacctaat tgaccactat agttaaatcc acatgaatat aaagttccat cattcttgat
     2881 tataaaggtg tatgcctgtc cacaagcaat ctttttaaca ttatcaatat caacctttgt
     2941 aaatatattt ctttgtgcaa tatcacctaa gcctaactct ccataactat tatttcctgt
     3001 actccaaata ctcccatctt ctttttgtat aaatgtttga ttatttccac atataatttc
     3061 ttttacatta tcaatatcaa ctttagtaaa cacatttcta ttagtagtat cgcccaaacc
     3121 taattgacca ttagaattaa gacctgtact ccacacagta ttgtcatttt ttaatataac
     3181 tgtttggttc cagccacata taactttttt cacattatca atatcaactt tagtaaacac
     3241 atttctatta gtagtatcac ctaaacctaa ttgaccatta gaattattac cactattcca
     3301 tacagtccca tcatttttca atacaaccac atgcattttc ccacatacaa catcttttat
     3361 attttccaca ttcattctag taaatactct tttgccagca gtatcaccta aacctaattg
     3421 accataggaa ctactaccac taccccataa agtattgtca ttctttaata tgaaagaagt
     3481 atctcctaat acgattttat aattgtttgc atattctgtg aaattatttt ttagttctat
     3541 attaacttta gtaaatacat ttctattagt agtatcacct aaacctaatt gaccactagt
     3601 attcatccca catgagtata aagttccatc attttttagt agaaatgtag aatcaccact
     3661 agatattcca tttttaatat tttcaatatt aatcttagta aatattaact tatcaaaat
//
LOCUS       DAYAKB010000166         3687 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.171, whole genome shotgun sequence.
ACCESSION   DAYAKB010000166 DAYAKB010000000
VERSION     DAYAKB010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3687
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.171"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..903)
                     /locus_tag="ACGI3L_003700"
     CDS             complement(<1..903)
                     /locus_tag="ACGI3L_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9199379.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNAN"
     gene            complement(1408..3426)
                     /locus_tag="ACGI3L_003701"
     CDS             complement(1408..3426)
                     /locus_tag="ACGI3L_003701"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9199380.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIR
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT         1114 a          598 c          434 g         1541 t
ORIGIN      
        1 attagcattt gttatgtata ctttttccac atcatgattt ttatctattt cctttgctat
       61 caataaagat gtctcatatc tattagaacc atttaaacgt gtttgactag catttacagt
      121 tgatttaatt tgattagcag tagttttaga aatagcattc tcatctccaa ttataattat
      181 atctttaggg tttaggcgct ttaattctga ttttacacta ttaggtacat tgtttttttc
      241 aaccaaaagt attggtgcat tatatgtggt tgccagtgga gttgatataa tgccatctat
      301 acttacatcc ccatttatta taactacctt atctgaacca tttttccagc cctctttact
      361 tattttaact gctgtttcat atctatcact tcctgtaagt tctgtaatag gtgaagaagt
      421 ttttctcaaa tatttattta catcttttct agaagttata tcttcaatta tacattcctg
      481 tgttacatta tagtctttta aatttaatcc cagcttttct aggtcttgtc tgtttaaagt
      541 tttaggatta tttttgctgt ttattgttat cccttgtagt tcccaaacat ttagatattc
      601 tgggtcttgg ttataattga tagttccttc atatgcccca gttgattgat tgtaatttag
      661 agttgtattc aatggcatgt catagcattt atactttaat gtaatgctat ctgcatctgg
      721 tttttcttta aatttgacac taacttttga tttgctacct aaaacgatac tttttttctc
      781 taagtttata tttaaatcag cgttattttc catagcatta gattcagtag caaatgccat
      841 tgtaggtgcg acgattgcca ttgaaagaat ccctgttgtt aataattttg tatttcttct
      901 catattaatc tccttactta acataaattt ctactttatt tttaatcttt taacttttga
      961 aaatatgtca aagtgtatct aacccaaaat ataaataata tataagtaat atataaaaat
     1021 aaacttataa aactcaaaaa ataaaaaaat taaatatatt taatacattt aattatctat
     1081 actatatcat ttattgacat aaaaatccac aaaaaacaca caaacacaca ataaaatata
     1141 gtaattaagc ttttattgtg tattacaaat gaatactcca actcttgaca attaactgta
     1201 gccttaagat atgtaaattc ttcatataat ataaatcctt ttacaattaa tcataaaaag
     1261 actgtatata cctcatttcg cacttatatg cacaatgtat atacagtctt tattactatt
     1321 ataattacat tcttatctta tagctttagt ttaaatttaa aattgcagat taatttattt
     1381 taaatttttc tatgctctca ttgtagacta ttttaatgaa tcttctatgc ctttacctat
     1441 ttgtgtaccc atttctttta ctttatttga tgtattaagt aaactcatat ctttctcatt
     1501 atccaaaaat gcacattcta caagtacagc tggcatatca ttatttctta aaacatataa
     1561 ataatctttt gtagggtcag ttgatagtgt tcttgttttt gcacctctat tttttagatt
     1621 aaatttctct aagattctat ttaatatatt tgtagctaca gttttagtag tccctccatc
     1681 tttatcttta agcttataaa atacttctac accattccca gttgtatcag atgcattata
     1741 gtgtatactc gtaaataaat ctggtctcaa agagttagat aaagcagttc tatttccaag
     1801 agataaagtc ttatctgtgt ctcttgtcat tattacattg aatccctttg aacgtaaata
     1861 ttcagttgtc gcaagtgaag tatttaatgt atagtctttt tctctaatac cccctaatgg
     1921 tttacctgtt gttccagtgt ccgaaccacc atgtcctggg tcaatcataa ctgtcttgcc
     1981 cccactattt cctggttctg ttggagttgt attgtgttta gataatgatg atgctataga
     2041 gctcattacc ttagaagtca atcctccacc tattttatat accttatttg ccgatttagc
     2101 ttctaagttt tctttatggt atgcagatac atatgtcttt ggtgttataa gtattggaga
     2161 ttttaagttc gcagccaatg gacctgctgc taaagcatca acaagtacat ctgatttagc
     2221 tactaaaaca gcctctaact catcatctgt atagaatttt tttattacgt ttgcatttgt
     2281 ttcgtgtcta tctgctccat atactctatt attagtaaca ttatctttag ttatatcatt
     2341 taccttattt ataacatttg ttgatatcat ttgagggcca cctataaaat aagcattttg
     2401 taaatcctca ctctttaacc atttatatgt gttgtctgta atactatttt tatcagttaa
     2461 tataattggt tgcttgtctt gacctgcttt tgctgctata gtaagtgcat ccacttctcc
     2521 gccattagca tttgttatgt atactttttc cacatcatga tttttatcta tttcctttgc
     2581 tatcaataaa gatgtctcat atctattaga gccctttaga cgtgtttgac tagcatttac
     2641 agtcgattta atttgattag cagtagtttt agaaatagca ttctcatctc caattataat
     2701 tacatctcta ggatttaaac gctttaattc tgattttaca ctattaggta cattgttttt
     2761 ttcaaccaaa agtattggcg cattatatgt agttgctagt ggagttgata taatgccatc
     2821 tatacttaca tccccattta ttataactac cttatctgaa ccatttttcc agccttcttt
     2881 acttatttta actgctgttt cgtatctatc acttcctgta agttctgtaa taggtgcaga
     2941 agtttttctt aaatatttat ttacatcttt tctagaagtt atatcttcaa ttatacattc
     3001 ctgcgttaca ttatagtctt ttaaatttaa tcccatcttt tctagttctt gtttgtttaa
     3061 agttttagga ttatttttgc tgtttattgt tatcccttgt agttcccaaa catttagata
     3121 ttctgggtct ttattataat tgatagttcc ttcatatgac tcagttgatt gattatagtt
     3181 taaagttgta tccaatggca tatcatagca tttatacttt aatgtaatgc tatctgcatc
     3241 tggtttttct ttaaacttaa cactgacttt tgaggtacta cctaaaacga tacttttttt
     3301 ctctaagttt atatttaaat cagcgttatt ttccatagca ttagattcag tagcaaatgc
     3361 cattgtaggt gcgacgattg ccattgaaag aatccctgtt gttaataatt ttgtatttct
     3421 tctcatatta atctccttat ttaacataaa tttctacttt gttttttaac cttttaattt
     3481 ttgaaattat atcaaagtgt ttttacccaa aattataaat aagtacataa aaaataaact
     3541 tctaaaaaaa ttataaaaac aaaaaataaa aaaattaaat atattgaata tatttaatta
     3601 tcttcactat atcatttatt gccaaaaaaa tctataaaag acaaataaaa acatataaca
     3661 attgtaggtt tattaaattt aatacaa
//
LOCUS       DAYAKB010000167         3682 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.172, whole genome shotgun sequence.
ACCESSION   DAYAKB010000167 DAYAKB010000000
VERSION     DAYAKB010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.172"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            77..2779
                     /locus_tag="ACGI3L_003702"
     CDS             77..2779
                     /locus_tag="ACGI3L_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9199381.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            2813..3511
                     /locus_tag="ACGI3L_003703"
     CDS             2813..3511
                     /locus_tag="ACGI3L_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199382.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         1481 a          391 c          658 g         1152 t
ORIGIN      
        1 aaaaatactt cttaactaca attttatatc ggaattgata ttataatagt aatgaatggt
       61 gtaaggaggt tttttaatgg atagacctaa tcctgatatt ctattagaaa aaattaaaaa
      121 tgaagaagaa aaactaagta gaggtcaatt aaaaatattc tttggttatg cagctggagt
      181 aggaaaaacc tactctatgt tggaatctgc acaaaattta aaaaaagtgg gtgtagatgt
      241 agtagttgga tatattgaac cacacactag accagaaaca ttggctttac ttgatggctt
      301 ggaaattctt cctgtaaagg agatagaata taaatctata aaactaaaag aatttgattt
      361 agatgctgct ttagcaagaa aaccagaagt tatattagta gatgaatttg cccattctaa
      421 tgttgctggg ttaaggcata caaaaagatg gcaagatata gaagaattgc tgttagcagg
      481 cataaatgtc tacactactg taaatgtaca acatttagaa agtctaaatg acattgttga
      541 gataattaca aacgtatcag ttaaagagac tataccagat aagtttttgg atacaaatac
      601 acagttagaa cttatagatg ttgaacctga tgtacttctt gaaaggttca atgaaggtaa
      661 gatatataag aaagaacaag ctactagagc aaaaaataat ttttttataa aagataacct
      721 ggttgcactt agagaaattg cacttagaaa aacagcagag agagttaata aagaagttca
      781 aatgaccaga ctatcaaagg gtgatgtaac tgtaatacct acatcagata cacttcttgc
      841 atgtataagt ccatctccat cttcagcaaa agttattaga actgcatcca gaatatcaga
      901 cagtacattt gcaaaatgga tagctttata tgttgaaact ccaaacacag caagacttcc
      961 atttgatgaa caaaaacaac tacaaaataa cctaaaatta gctaagaaat taggtggaga
     1021 aataattgtt ttacatggtg aaaatataat agagcaaata cttagaattg caaagctgag
     1081 aaatgtaaca aaaattgtaa taggtagaaa tcattcaagt aataaaagat ttagtaaaag
     1141 atttaaaaaa gatatagttg acaaattaat tgatgaagtt gattatatag atatacatat
     1201 aattccatat aaatttgcct cagatgttaa atacaaacct aaaaaggata aatcatcaat
     1261 aaaatctaaa tttaaaatta gcaaagttga ttttataaaa cttatattta ttactttgat
     1321 gataagtatt ttagcatatg cagtacaaag catgggattt ataagagaaa atatattgtt
     1381 aatatatatg ttgggtgtag ttttagtttc tatgtggact aaagggtata gtacaggtat
     1441 aataagttct gtatttaata tagttctttt aaattatttt tttacagcac cattatatac
     1501 attatctata gcagattcaa actatatagt aacactggtt gtattctcaa tagtaggtat
     1561 aataactagc actcttacgt ctaagataca gcatgaagca gaaactgctg ctaaaagaga
     1621 agaaaataca aaaatgatat atcaaataat taagggattt ttaagattat caaataaaga
     1681 tgatatagta aacaaaggta tagaactttt gtctcttagc ttaagtagag atgtaatttg
     1741 ttatttaaat gtagataagc ataataaatc aaagctttac aaaaaaaata ctaataataa
     1801 ggataaaaat gatttggata gtgaagatga aaaagctgtt gcaagttggg ttttatccaa
     1861 ttcaacagta gcaggaaatg acacggatac acttcctggt tcaaagggat actatatacc
     1921 aattgtagga atgaatttaa ctttaggagt agtgggaata tcatgtattg attcaaaatt
     1981 ggatacagaa gatataagct taattgaaac aataattgct caaatggcaa tagcgcttga
     2041 tagagaaatc ttgtcagaag ctaaagaaaa taccaatctt gagattgaaa gggaaagatt
     2101 aagaagtaat cttttaagag cagtttcgca tgaccttaga actccactag caggaatatc
     2161 tggtgcagta agtacaatta taaaaaacaa gggtactata ggtcaagata taatagatga
     2221 attacttagt ggtgtatatg aagatactca gtggttaata agacttgttg aaaatttact
     2281 tagtatgacc aagatagatg aagggaaatt ggaagttaaa aaacattctg aactggttga
     2341 ggaaattata tcagaagcgt tacaaaaaat aaaaaaaaga attgaaaatg cacttataga
     2401 tattaatata ccagaacaga tattatttgt tcctatggat gcaaaattaa tagaacaagt
     2461 tttaattaat ttaatagata attctttgaa atattcaaag gaagattgta agatagagat
     2521 aaatgtatat gagaaagatg attatgtttg gtttgaagta tctgataatg gtcctggtat
     2581 atcaaaggaa cttaaaaagc atatctttga cagatttttt actggagaag aaggagctaa
     2641 agattccaga aagggtgttg gacttggatt atcaatttgt aaatctataa ttcaagctca
     2701 taaaggtgaa attatggtag aaaacaataa agataagggt tcaactttta agtttagttt
     2761 gcctaaggaa aatgaatagt tttaaatttt aaaattagtt ttggaggaag aaatgagtaa
     2821 aaaacttata ttgttagtag aggatgataa gacaataaga aaatttatat ctactgcact
     2881 tttaacacag gattatgatg tcaaggaggc tataactgga aaagaaggta tatctatagc
     2941 tgtctcatat tctccagatg ttgttctttt agatttaggc ttagaagata tggatggaat
     3001 agaggtaata aaagctatca gacaattttc aaatatacca ataattgtag tttcagctag
     3061 agagcaagat agagacaagg tagaagtatt tgatgcaggg gcagatgatt acttaacaaa
     3121 accattctcc atagtagagt tattagcaag agtaagagta gcatttagac attcacaagt
     3181 agaagctcaa caaaaagatg atgttaaatc tacgtttgaa gtagataaat tattgattga
     3241 ttttgataaa agaaaagtta ttgttgatga tgttgaagtc catttgacac ctattgaata
     3301 taatattctt tcattacttg caaagtatca tggaaaagtg cttactcata attttataat
     3361 aaaagaaata tggggtagtg ttatagggaa tgagactaag tctttaaggg tctttatggc
     3421 aacgttaaga cgaaaaatag aaaaacaacc tgcaaaccca agatatataa ttacagaagt
     3481 tggtgtagga tacagattaa atgatgaata gttgtaatat attaattatt agattatgtg
     3541 cttattaata tatattaaaa ttatatagtt tagttaaaat aagaatgaag tgtatgtgct
     3601 tgttgtcagt ttagcacatg cattttattt tttagctttt ttagtatcaa taatttttta
     3661 gtatcaataa tatgaaatat gt
//
LOCUS       DAYAKB010000168         3340 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.173, whole genome shotgun sequence.
ACCESSION   DAYAKB010000168 DAYAKB010000000
VERSION     DAYAKB010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3340
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.173"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            108..1187
                     /locus_tag="ACGI3L_003704"
     CDS             108..1187
                     /locus_tag="ACGI3L_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFG9199383.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSDVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            1277..1909
                     /locus_tag="ACGI3L_003705"
     CDS             1277..1909
                     /locus_tag="ACGI3L_003705"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HFG9199384.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            1953..2486
                     /locus_tag="ACGI3L_003706"
     CDS             1953..2486
                     /locus_tag="ACGI3L_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFG9199385.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            2535..3221
                     /locus_tag="ACGI3L_003707"
     CDS             2535..3221
                     /locus_tag="ACGI3L_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFG9199386.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
BASE COUNT         1332 a          338 c          581 g         1089 t
ORIGIN      
        1 ggattttttc tagtaaaaga cagctttatt gttgtatcat aaaataaatg atatggatat
       61 ttaatggata taaaaatagg agtaatattt atattaggag gaactatatg aaaatagcaa
      121 tatttttagg agcaggagct tcagcagcag agaatctacc tattcaaaat gaacttttta
      181 gcgaatattt taaaaaacta aatcccacaa attataatac caaaatgaat agagaattgt
      241 atattttctt taaacagatg ttcaatattg atatagtaaa agataatata gataatgcaa
      301 attttcctac ctttgaagaa gttttaggtc ttttagactt agcagaacaa agaaaagaag
      361 catttagaaa ttttggacta gaaaatctaa ataacagaag tgatagtata cgttttttaa
      421 gacaatattt aatactgcta atggctgaag caattcataa tacacctaga acagataata
      481 aatatcataa acttttagtt gaaaatcttt tggaaaatga tttgcttctt gatactactt
      541 ttattagtgc aaattatgat atacatatag acaatacagt tactggatta agagataaga
      601 atgatttgcc aattatgctt gattatggtg tggagtttac aaattttaaa gaggagttaa
      661 attggagaaa accaaaagaa ccattaatca aattatataa gatacatggg tcattgaatt
      721 ggctttattg ccccatttgt aatagtgtaa ctcttacacc acatgaaggt ggtgtcatga
      781 agcttattga aaatagttca gagacaaaat gtttagagtg tggtgagtta acagaaccta
      841 ttatagtgcc accaacatat tttaagaata tgtcaaacat atttttaagt gatgtttgga
      901 atgaaacaga aaaaacttta agagatactg accttttaat attttgtgga tattcatttc
      961 ctgaagctga tatgcacata aaatacatgt taaaaagagt gcagactaat agaaaaaaac
     1021 ctcctcttaa gataatggtt tttaataatc attcacaaaa acagagaatt actttaaaga
     1081 aagaagaagg aaggtataaa cgttttttgg gtgaagatgt tatatttact gataattctt
     1141 tccaagattt ttcggtaaat cccttgaggt ttataaaaaa tatatagtag tatggtatat
     1201 aatggaataa aatctgatag aaataaaatg aatttaggta tataatagaa aataaaaaca
     1261 tagggggtat ataaagatga aggtttttga tttaactcat gtgacacata atgacatgcc
     1321 tgtatatgca gagcctaata gaccagatat caagaaagta gctattattg aagaaaatgg
     1381 ttatcaagaa acattaatta gtgtattttc tcacaatgga actcatatgg attcaccaag
     1441 acatatgtat actaaaggtg agaccctaga taagttggat atagaaaatt ttgttgggaa
     1501 agcttatgta ttggaacttg aaaagggaaa tgagaatata gaattagaat atctaaaaaa
     1561 atatgaagat gaaataaaaa atagtgattt tataatattt aaatcaggtt ggtcaaaatt
     1621 ttgggataaa aagcagtact atgtaggtta tcctacatta acaaaagaag ctgcaaacta
     1681 tatagctaat actaatataa aaggcatagg aatagatatg ctatcagtgg atagatatga
     1741 cacatcagta tttgaagtgc atcatatttt atttgaaaaa ggaaaaataa tcatagaaaa
     1801 tcttacaaat ttagaaaatg ttccagaaaa atttctattt atagcagcac catttaagta
     1861 taatgatgct gatggagctc cagtaagagc aatagctata gtagaataat acctcacaat
     1921 gatattatga tgaagtgttt aaggagaaaa gtatgagtga tttaaataat aaaaaagaac
     1981 aagatgaaaa tgaatctagc atgaatgaaa ctaaaatata tgatattttg gataaattaa
     2041 atgttgaata tgatgtagta gagcatgaag ctgtatatac agcagagcaa ttagtcattt
     2101 tagatggaat aacaaagggg tgtcaatgta aaaatttatt tttaagaaat gccaaaggaa
     2161 ataagtatta tcttattgta gttaaaggag aaaaacaagt tgatttaaac tcacttaaag
     2221 ataagatagg aagttctaga ttatcgtttg cttcacctga aagactatac aatgtactta
     2281 aacttcttcc tggaagtgta aatccttttt cattaataaa tgatacagaa agaaaagttg
     2341 agctttacat agataaagat gtaattaaag aagattactt aaattttcat cctaacataa
     2401 atactaaaac tgtaaatata tctagaaaag gttttgaaga atttttggaa tatttaaaat
     2461 atccaataca aagtatagat gtttaggttt taataatagg ataaatttca attagctaat
     2521 cgaggggaga aaaaatgttt ggagtaatag caaatagtct agcaattgca ggtggatgta
     2581 tagtaggtct tataataaaa ggaggattac ctcaaagagt aagcgatact ataatgaatg
     2641 gaattgcctt atgtgtattg tacattggta tatcaggagc actagaagga aaaaacacat
     2701 tagtgacaat aatatccgta gctgtaggtg ctctgatagg agaattaata gatattgaca
     2761 aatgggtaaa taagttgggt gcttttttac aaagtaaatt ttctaaagga aataaaaaag
     2821 attctatagc agagggtttt atatcatcta gtttattatt ctgtatagga gccatggcag
     2881 tagttggttc attagaaagt ggtcttacag gaagtcatga tactttattt gtaaaatctg
     2941 ttatagatgg aatagcttca attatattta ctgcttcttt aggtataggt gtaatgtttt
     3001 ctgcaatatc tgtatttttg tatgaaggta ttatatgtgt gggagcatca tttttaaatg
     3061 gatttttaag tgatcctgta gtcacagaaa tgacagcagc tggaagttta ttaattatag
     3121 gacttggtct aaatgtactt aaattaacga atataaaagt agccaatttg ttaccagcta
     3181 tatttatacc aatattattt ggcgtatttg gaataattta aaaataattt aaaaataatt
     3241 taaaaataat ttaaagagta ataacctaag atttgtctaa attttttaga aactttagac
     3301 aaatttttta tttagaagga aaatagcttt tatcatcaaa
//
LOCUS       DAYAKB010000169         3289 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.174, whole genome shotgun sequence.
ACCESSION   DAYAKB010000169 DAYAKB010000000
VERSION     DAYAKB010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.174"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            105..482
                     /locus_tag="ACGI3L_003708"
     CDS             105..482
                     /locus_tag="ACGI3L_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199387.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            complement(919..1182)
                     /locus_tag="ACGI3L_003709"
     CDS             complement(919..1182)
                     /locus_tag="ACGI3L_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199388.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            1498..2073
                     /locus_tag="ACGI3L_003710"
     CDS             1498..2073
                     /locus_tag="ACGI3L_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199389.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            2171..3169
                     /locus_tag="ACGI3L_003711"
     CDS             2171..3169
                     /locus_tag="ACGI3L_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HFG9199390.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
BASE COUNT         1320 a          282 c          506 g         1181 t
ORIGIN      
        1 tattaataaa tttggatgag atattttaaa taaaaccttt gactcgaaaa gtctattaat
       61 atagtattta attatgtaga agtttgagag gagtgtaaaa tcatatgact attactaaga
      121 taccaccagc agaattaaaa gtcatgaaat ttatttggag ttcagatttt acagtagcat
      181 caaaagatgt cattgaagct atggaaaaac tatataattg gaagcaaact acaacactaa
      241 cacttttatc aagattagta aataagcaat tcttaagtgc aagaaaaatt gatagacata
      301 cacattatac agttcttatt ggagaagaag agtatttaca ttttgaaaca aaaacttttt
      361 tagataatat gcatggaagt tctattgaga gttttatgaa atccttgttc aaaaaggggg
      421 taaatgaaga agaattgaac tctgttgaaa aatgggttaa ggatattaaa aaagatgaat
      481 aatttggtgt agttaattat cataaaataa atagttttta caataattag ttaaatgaat
      541 caaatataaa gttttatgta aaatttgtga tttttataaa tatttttgtc ttgttattta
      601 atattaatac aataagtttg atgtaaaatc aaacctgttt gaatttaatt tatattgggt
      661 ttgtcattaa tattatttta gtttgatatt gtatacgaat ttaaaagtca gaatttttgt
      721 atattaatca tgtaaattaa ttgttttaga tataaagggc ataattttat ttttgttttg
      781 attatttcta gggtaagata agtatacaat agattgtatt aaacatgctt atattgatag
      841 atttgagata aatattgaga tatattaata attattaata taaaaaagtt cctagttttt
      901 aggaactttt ttatttgatt aatacagagt atgagttttt gcttcagcta tagctcttgc
      961 tgcactttta ggtttttcag tattttcttt tttgtaaaat ttaatcactt cttctaaatc
     1021 tttattttca atattatgtt ttttgttttc aagaatataa tttacaattg attcatttat
     1081 caaatctgtc aaaatattat tttcgtcatt agttatctta gacatttctt gtaataaaat
     1141 ttcattaact tctactgtaa tttgttttgt attttttatc atatcaacca cctcttaaga
     1201 aaattatatc atctcaaaaa aataaattca atatgtttta aaattataga attttaattc
     1261 ttaaattcta aaaaagagaa aattagataa agtagtttta gattttaaaa gattaataaa
     1321 aaatatttaa agataaaagc tttattctat atgattctaa gatagaggat ttataagtgt
     1381 ttaaggtgaa ttaaatataa gacaacttct taaagcaaat gggtgtggta tttaaatcta
     1441 aatgtagaca tataatatta aatatgctaa tatatcaaaa taataagggg ggaatttatg
     1501 aagcttaaag aagcattgat tacatgtgtt gtatgtagtg tatgtttaac tccattattg
     1561 gtaaatggag aaacaaaaat agatgcagat cattgtaaag aatctatagt aaatatagat
     1621 actatagtaa agtcaggtaa aagctttaat tccaagtata atcaaggtat ggaagattat
     1681 aaaaatagtg atgagtataa gttgaaagta caaaaggaga aactacaaaa tcagttaggt
     1741 attaaaataa agaagttagt acctataact tttgaagtta gttattacac aagtcttaat
     1801 caagaaaatg gatatggagc gataactgct acaggagatg atttagaaga tggttttgta
     1861 gcaaacaatc acttaagttt tggaactaag attattgtag atggaaaatt aaaaactgtt
     1921 atggataggg ggtctagtaa gtattttagt aattctaatg caatagatgt atttgtgccc
     1981 aaatggagta atgaaagtga atcagagtac tatgatagag tcaataatat gggaagacat
     2041 tacaaaaaag gctacattat tgttgaagaa tgatgttctt tgaagtaata tgtattgatt
     2101 gtagtattta atatatatat aataaatata aaactattag tacaatgaga tatattacta
     2161 ggagggcaat atggaacaat cgtttataaa tggaaaagta aacttattaa tagaaaatta
     2221 caaagcatta aatgaagtta aaggttcttg gcaaatggga ttgatacaac atagttgtgc
     2281 acttgcattt acccttaaga acaagagaat aagtcctaga ttagtggaag aacgaataga
     2341 gcttattaaa aaaaatactg gattattctc taattttaga ggatataata tgttttatat
     2401 ggcaacacta ctttcgtttg aatcaaatcc agaaagtagt tttaagatga ttttagatat
     2461 atacaaagaa cttaaaagtg aaaagttttg gggcgataca tatttaccac ttacagcatc
     2521 aatagtttat gaaaatagag agaaaatgga ttatcttaca tgtatatcaa aaatgaaaat
     2581 aatatatgat tacatgagga aaaaacatcc atttctaact tctagtgatg actattgtaa
     2641 tatagcactt attgcaattc attcaaaaaa tttagatgaa gatttagaat acatagaaaa
     2701 atgttatgaa tttctaaatg aaaatggttt ttataaagga aatgatttac aagcattatc
     2761 ccaaattctt ttatttagtg atgatagaac tatgcttaaa tgtaaaaaga ctattgaact
     2821 taaaaaagca tttaaagaaa atgattgtaa aatgaattat tatggatatc caataatagg
     2881 agcaatttca ttattagatt atagagaaga tgaaataata gaagagataa aaaatgtttc
     2941 aaataaactt aaagaagaaa aaggctttgg aaattggtct ttaggaaaaa gtaatagagt
     3001 aatgattagt tctgctattg tagcttcaat ttatgcagat ttgatacgaa atgagaataa
     3061 tataggctct ataactaata atatattttt aaatattgtt gttgctattc aaattgcatg
     3121 tgtaatggca gcaacaagtg cagctatagc atcttcttca tcaaattaat aagatttatt
     3181 gaagttggat atattaaatt taataataca atttatatgt ttaaaaagaa gatagtatta
     3241 cattttaatt aactgtgata ttatataata tgaaacatat aattaatat
//
LOCUS       DAYAKB010000170         3222 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.175, whole genome shotgun sequence.
ACCESSION   DAYAKB010000170 DAYAKB010000000
VERSION     DAYAKB010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.175"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            23..817
                     /locus_tag="ACGI3L_003712"
     CDS             23..817
                     /locus_tag="ACGI3L_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199391.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            818..2878
                     /locus_tag="ACGI3L_003713"
     CDS             818..2878
                     /locus_tag="ACGI3L_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit/CPBP
                     intramembrane protease"
                     /protein_id="HFG9199392.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         1236 a          322 c          523 g         1141 t
ORIGIN      
        1 cgagaaagga gtggtttgat aaatgattga ggtagataaa ttgtgtaagt cttttacaag
       61 ggttgtaaaa gatgataaga ataaaagttc aataagaaag ctaaagaaag taaaaactaa
      121 aaaagaagaa ttttttgctg taaataatgt ttcatttaaa gttatggaag gtgaaattgt
      181 tggaatatta ggtccaaatg gtgcaggaaa gactacatta cttagaatgt taggtggcat
      241 attaacacca acatcaggaa gtataaatat ttctggatat gattattcaa tagatagaaa
      301 ttcagcaaaa aaagaaatag gttatctctc tggaaataca aaactatatg gaaggctttc
      361 tccgagagaa cttctaacaa cttttgcaag tctatatgag atgtcaaaag aagatataga
      421 agaatcaatt gaaaatattg taaaaataat ggatatgagt gaatttatag ataatagaat
      481 tgaaaatcta tcaactggtc agactcaaag aacatctata gctcgttgtt taatacattc
      541 tccaaaagta tatatttttg atgagccaac actaggtctg gatgttttaa gtagtgcatc
      601 tattatagat tttatgaaga atgaaaaact aaggggaaaa actgttcttt actcaactca
      661 ttatatggaa gaagcagaaa ctttatgtga caagattttt atgattcaca atgggaaaat
      721 aattgcatca ggaacaccac agagtttaaa agaggaatct ggagtaaata atttgagaga
      781 tgtattcata aaacttgcca gaaaggagga catttaaatg agaagtaaga ttgtaaaata
      841 catatttaaa aaagaaatgt tagacatatt gagagataaa aagactttat ttatgatgat
      901 tgttgtgcca cttcttttat atcctttact tatgttatta atgattcaag taatgaatat
      961 gtctgcaagt agtatgaata gtaaggacat taatatagct tttaataata aacctaataa
     1021 ggtgttagta tccatgattg aagatgataa tttagaaaaa gatactaaaa atacttcaaa
     1081 tgataaaggc aaaataagag tgttagatgt agataactat aaaaagtcat tagaagaaaa
     1141 taaaattgat gcttatataa agatggaaga aaaaaaatca tctataaatt atcaaatata
     1201 tataaattct tctcaagaaa attcttctaa tgcactaaaa agaattgaaa ctgttttgga
     1261 taaatataaa agatttacca tagaaaaaac tttatctgaa aaaggattag atgtacaagc
     1321 tactttagaa ccaataacat atagcactgt agatgttgca aagacggaag aagtggcagg
     1381 atacttttta ggtcagatac ttccatttat attaataata ggagttttac taggttcaat
     1441 atatccagca atagatgtta tggctggaga aaaggaaaga ggtacattag aaacattatt
     1501 tacactgcca atatcaaact tagaactggt tatgggaaaa tatatggcag tttctcttag
     1561 tgcaatagta acagcaattt taaacatttt atctatggga ctgactatgg catttatttt
     1621 agttagtgga ggtattagta gccaatttgg ctttggaaac tttaattatg gagacttagt
     1681 cttaccaatt ataactactt taatttgcat atgtcttttt tcaatggtag tttcagcaat
     1741 aagtatgtgt gtatgttcat tagcaaaaag ttttaaagat gctcaaaact acataacacc
     1801 tcttatgtta attattatga taccatcata tgtttctatg ataccaaata tagtattaga
     1861 tagagtgaca gctgtaatac ctgtagtaaa tatatcttta cttataaaaa gtgtattatc
     1921 ttttaaaagc gatttaaatt taatagcctt agttttagca tcaaatgtag cctttgttat
     1981 attggcaatc atactactgt ctaagatgtt caattctgag gaaatacttt ttggtaatag
     2041 taagagtttt tctttcttag agaaaagaag taatataaaa aaagggtcta taccaactgt
     2101 aagtgatggt gttattttat atgcagtagg attagttcta ttgatttatg ttggttcttt
     2161 agttcaaatt aaatttggta tggcaggtat tataatgaca caattcatga taatttcttt
     2221 accattatta tttgcatact atattaaagc tgattttaaa gaggtattta gcttgacagt
     2281 tcctaaatta aagcatgtgt ttgggagcat tgttctttgg attggtggat acatacttat
     2341 tatgattata acacagctaa ttttattctt atttcctcaa aatatggaag ttgctgaaag
     2401 tttaaataag gctcttttta tcaaagatag tgttttactg aatttactag caatagcttt
     2461 attaccagct atatgtgaag aaatgttttt taggggattt atattttctt catttagtaa
     2521 atcaaaagat aaaaataagt ctatcaaact cgctataata tgtagtgggg tactatttgg
     2581 tattatgcat atggatttta ttagaataat tccaacatca atattaggta ttatatttgc
     2641 atacagtgtg tataaatctg gttcaatatt tgtatcaatg ttattgcatt ttttaaataa
     2701 tagtgtagca gttgtgttaa atcattatac aactggaaat ataaccaact tatataaatt
     2761 tgttgaagtt gatttttcga acttaaatgt gcttaaattt gccttaattc ttctaataag
     2821 tcttatatta attatgttag gattaagagt tttagataga aagtctttaa gaaattaagt
     2881 ataaagttat tatatagatt aaaatattaa taagcactaa agtatatgga tatatcttgt
     2941 atataaaaat actttagtgc tattttatat attttaatta tatgaattat ttatcgtttc
     3001 atttatgtaa tgaaaatgtt atataaatga aacaataaat aatttttatt ttagaaattt
     3061 atatttaaat aatcaagttg aaagtgagat actaaaaaaa ttaatttagg aattatttga
     3121 tttattcatt tataaaaatt aattactgat ttgtcgaaac cattgtaata agaaaaaaat
     3181 gaaaaaataa agtgtgaata tgttgcaaat actgtatttt aa
//
LOCUS       DAYAKB010000171         3211 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.176, whole genome shotgun sequence.
ACCESSION   DAYAKB010000171 DAYAKB010000000
VERSION     DAYAKB010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.176"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..623)
                     /locus_tag="ACGI3L_003714"
     CDS             complement(<1..623)
                     /locus_tag="ACGI3L_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HFG9199393.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTI"
     gene            complement(623..1483)
                     /locus_tag="ACGI3L_003715"
     CDS             complement(623..1483)
                     /locus_tag="ACGI3L_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199394.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            1618..2418
                     /locus_tag="ACGI3L_003716"
     CDS             1618..2418
                     /locus_tag="ACGI3L_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HFG9199395.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            2443..3012
                     /gene="yfcE"
                     /locus_tag="ACGI3L_003717"
     CDS             2443..3012
                     /gene="yfcE"
                     /locus_tag="ACGI3L_003717"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HFG9199396.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT         1200 a          469 c          385 g         1157 t
ORIGIN      
        1 attattgtta aaaatgtcat actatataaa tttatatact tagtattagc tatatcagtt
       61 acataatttg aaagatatac tcctccaact ttactataat taaaatgctt tacttgatat
      121 acaatcatac taatcatctt caaaagactt ccatatacaa agtaaattaa aatacttact
      181 ataaaaccac aaactttcat ttttccatat ccaaacttaa aaattaaagg cagtaaaatc
      241 gtcaaaattg ctaaaaatat atttacagaa aaaaatacat catttaaaac catatttcta
      301 aagaacacta gtgatgtcaa tttacttagt aaggacacaa ttattgttac agaaattatt
      361 aatcctacac ctaataaata ttttgagtaa actatatctt ctatactaac tggcatactc
      421 cttataaaaa tccttgaatc attttcataa tcacactcaa atgtatttat aaatatcaaa
      481 taactaacaa caatacttac tgtataatat gaaattgaat taaggaaaaa ataaaacaca
      541 aaaaatagca atatgtactt taaattacgg ataccatctg aactaatccc tattattaaa
      601 tcttttctta ttaaattgaa catcatctca cctcatttac ataataatac attagttctt
      661 ctatagtagg atttttgacc ttatgcttat caatttctat caataggctt tttactttca
      721 agctatctcc aactttaaca agtgcctcat tataatattt atactctttc acaccaacta
      781 tgctttcttt aattgcttct aactctgctt tatttgccct aattatctta tattcttgtt
      841 ctattaattc tttcttaaca gtaaaaatct gatttcctct atttataaaa acaagataat
      901 cagcaatttt aattaaatta tcagtattat gagtagaaat tattacacta ctacttccat
      961 ttttcacaaa atcttgtaag tactgcatta tttcagttct tacaattggg tctatcccag
     1021 cagttggttc atccaaaatc aataacttag cattgtgact aagtgcactt gataacataa
     1081 gcttttcaga ttgaccttta gataaatttt caatatgcat attttcttct atatcaaact
     1141 tattaaggta ttcatcaaac ctttctctat caaaattctt ataaaataaa gaaactattt
     1201 ttctaaattc cttaaccttt aaatgcggat aaaattgtaa agaatcatat acaaaaccaa
     1261 tattgttttt aaagcttatt ggagaatttt caatagtttc attacaaagt tcaatttcac
     1321 cttcatctgc atcaataatc cccattataa tttttattaa agtcgttttt cccgaaccat
     1381 ttggtcctat aatcccaaca atatcccctt cctttaactc taagtttata ttatttaact
     1441 tgaattttcc taattttttt gtgatattcc ttatgctaaa cacatcttca cctcttatgc
     1501 atttttttat acccacctat acatatttta acacattcac tacaaaggtc atttataaat
     1561 ttataaatta agaattataa aactatgtta taatacaaag tatgaagagg tgaatatatg
     1621 aaaagaatta taactataaa tacaaaccaa ttaaataagt cccttgagac taaagaactc
     1681 ttaactagaa aacttatcaa tgctggcttt gaagtgtatt cagatattta tccagataca
     1741 gagcttatta tatcaattgg tggtgatggc tcttttttaa gaacagttag agatttcgat
     1801 tttcctgaaa ttcccataat gggaataaat acaggtcatc tggggttttt tcctgatatt
     1861 ttaccagata agattgatag ctttattgaa gcttatacaa aaaaagatta tattattcaa
     1921 gaaatgtcac ttcttaatgc ggaagtatat acaactacta gtggttctaa tatgcttgct
     1981 gtaaatgagg ttgttataag aggagacaag tctaggacta tacacctaaa tttaagcctt
     2041 gataataaac atatacaaaa ttttagtgga gatggtatga ttatttctac ttccacaggt
     2101 tcaacagcct ataactattc tgctggaggt agtattgttg atataaatct tgaacttatg
     2161 cagattacac ctttacatcc gataaatacc aatgcatata ggtgctttac atcaagtata
     2221 atatgttcaa atgaatctgt tataaagatt gcaccagaat atagatttga agattctgta
     2281 ttgattgtcg ttgatggagt tgagcacaga tttagacaaa tcgaaaatat aaaagttagt
     2341 atatctgatg caaaaataaa attacttaga atgtcaaact atgagttttg gcatagagta
     2401 tctgaaaaat ttttatagac tgtacttagg aggattttta atatgaaaat aggaataatg
     2461 agtgatactc atggtagctt actttacttt gaaaaagcgt taaatgtatt atctgattgt
     2521 gatgttttat tacatggtgg agatgtctta tatcatggac ctagaaatga tattccagaa
     2581 ggatataatc ctaaaaaatt tattgagaca ttaaataaat tagaaaacat tgtgattgta
     2641 aaagggaact gtgatgcaga tgttgaccag atggttatag aacatcctat tcagagtcct
     2701 tatgtcatga gccaatttgg tgaaattaga attatattga atcatggtta tatagaatca
     2761 gaagaagaaa ttattgacaa agcaaagaaa atgggtggtg acatattagt tttaggacat
     2821 actcatgtaa aaaagctata catggatgat aatttaatag taataaatcc aggaagtact
     2881 tctatcccaa aagatggaag ccattctgtc gcaattatag atatcataaa aactgatgat
     2941 gaggatgagc ttgaacttga tataaactta attgacatca atactggaaa tataataaat
     3001 atcaatgatt agtaaatttt taataaaaat aaaataagct ttaatttatt aaactcataa
     3061 taaaaacaag taaaccattt tatttctatc tcaattagaa gtttaagtac aataccttaa
     3121 acttctaatt aaatagaatc tggtttactt gttttattat atgctatatt gaaatataac
     3181 ttagtttact tatttcatta tatattatac t
//
LOCUS       DAYAKB010000172         3001 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.177, whole genome shotgun sequence.
ACCESSION   DAYAKB010000172 DAYAKB010000000
VERSION     DAYAKB010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3001
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.177"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..773
                     /locus_tag="ACGI3L_003718"
     CDS             <1..773
                     /locus_tag="ACGI3L_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="asparagine synthase-related protein"
                     /protein_id="HFG9199397.1"
                     /translation="DELFGGYNIYKEYSTMKSVVNSPTYIKSILGRVSELMPNIKGRN
                     YLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIYEYLLSNLYRDAQKNNYDYIS
                     KMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKDVFDVAKNLRMEQKINKNNTK
                     VLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDIVKETIYNSNVDEFIDKKYAI
                     KLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY"
     gene            complement(865..2301)
                     /locus_tag="ACGI3L_003719"
     CDS             complement(865..2301)
                     /locus_tag="ACGI3L_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFG9199398.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            2557..2955
                     /gene="tnpA"
                     /locus_tag="ACGI3L_003720"
     CDS             2557..2955
                     /gene="tnpA"
                     /locus_tag="ACGI3L_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFG9199399.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
BASE COUNT         1141 a          371 c          445 g         1044 t
ORIGIN      
        1 cagatgaatt atttggagga tataatatat ataaagagta tagtactatg aaatcagttg
       61 tcaattcacc tacttatatt aaaagtatat taggaagagt ttcagaactt atgccaaaca
      121 taaaaggaag aaattatctt tatagagcta caacaccatt agaaaaaaga tatataggaa
      181 atgcaaaagt ttttgaaaac agcgaagtaa aaagattctt ttttaagtat aaggaaaaga
      241 atatatatga atacctgttg tctaatttgt atagagatgc acaaaaaaat aattacgatt
      301 atataagtaa aatgcaacat atagatgtga atacatggct tcaaggcgat atacttcaaa
      361 aaattagcaa actttctaca gctgagcagg ttgaacttag agtaccattt ttatataaag
      421 atgtatttga tgtcgcaaaa aatttaagaa tggagcaaaa aataaataag aataatacaa
      481 aagttttact tagagaggcg tttagagaaa tagtcccaga acatgttgtt caaaggaaaa
      541 aattaggatt tccaactcca ataagagttt ggttaaaaga ttctctaggg gatattgtaa
      601 aggaaactat ttataattca aatgtagatg aatttataga taaaaaatat gcaataaaac
      661 ttttagatac gcatcttaaa ggtcatagag ataattcgag aaaaatatgg actatattta
      721 cattttgtct atggcatcaa ttatttattg agcataaaaa tgtcgagtat taatactttt
      781 ttcaatatta atcagagggc aaaagcatgc aatgttttca ccctcttgat tattatggaa
      841 taggataagt agaattttga ttgattagtt tactatctca ataaaattat tggcaaatat
      901 tttgacaaga ctactttcaa cagctaaatt taagttttgt ccatcatcat atccagcgga
      961 aatcaatcct agtaagtttc caaacatatc taaaagagct cctcctgaac taccactaga
     1021 gattggagct gtaaattgta tcatttgaac cgtttcaaaa tcacgaaaag ctgaaataat
     1081 tccatctgaa actgtattaa aaagacctag agggcttcca attgcaacta ttttttgacc
     1141 tctcacaggt tttttactga ctttaacagg tattggcttg cattttctat caacctttat
     1201 cacagctaaa tcataatctg aatggtattt tataatttgg taagatgtat aaactttatc
     1261 atcattttca aatctaacta aaaatgaata cccatcattg actacatgaa gattcgtaag
     1321 tatataacct tcattattta ttactactcc agaaccgctc ttaaacggtt tattttcgtt
     1381 attgcacaca acaatcataa caacagaagc tgataacttt gcaaggtctt cataagaaag
     1441 ttctacttcc tcatcttgta caattttttt agatgttaga tttgtgttat taagtgtatt
     1501 tttagagtta ggtttattcg tagtaggaga agtcttattg gtattttcac tgtaatttat
     1561 atttgtaata tgcctttcaa aaggtatttc taatatattt ggagtcttcc tagaaagttc
     1621 aaatagagta gaaaattttg aacattcagg atataaatca agaatatctt tatttggatt
     1681 tatatataaa atatcacacc caagttgtga taaaaaatat aagaaaaaaa gttcttgcct
     1741 tttaatattt ccaaagtata ctatctttgg tgaaatagta gtcttcacct tgttataaaa
     1801 taatttaggt agaaaatagt ctatccaaca caaaagttta actgcaaagt ttttgatgat
     1861 agaggatgta caatttggca tacttgtgga aaataaatct aaagtatttt taaatgcaat
     1921 ctttttagtc caatttaagg tgtcattttc tattttacat ggaaagtcga tattatataa
     1981 atcccaactg ttaaacttag aactattata aatattaaaa attttaagca tcttatctgt
     2041 ttgttctttg tcaaaattta tttttagatt gtttaatcta atatagggaa ttgtaggatt
     2101 attaaaaaaa taagtatcta tatttttaat tttttctatg tatttatcaa ttgaatcatc
     2161 aacacctata tatcttgtaa agtagacttc tttaatatat gaagaactct tatttttata
     2221 ggtagtatca gatataaatt caattagagg ttcagtagac ttttttattg aaatctttaa
     2281 tggtttaata gtacaaatca tattttttct cctataataa gatgatataa tctattataa
     2341 aacaacttaa aacaatatag tacaataatt ttgtagtttc aaaataaaat atgtacttgt
     2401 ttatataaat gatatataat tacaataaaa ttgccgaaaa gccctctcct ttaggtgtag
     2461 ggatgaaagg taaggtctta atataaaaaa agttagaata atgcttgtaa tctaataccg
     2521 ctactgatac cctatattta ggaggtgtta gtttttatgt ataaatctaa caaaaatata
     2581 gtttatgatt gcaaatatca tattgtattt tgccctaagt atcgtaaacc tgttttagtt
     2641 ggcgaagttg aaaagatgtt aaaagaaata ctaccatata aagcagatga acttggagca
     2701 gaaataatag aaatggaaac tgataaagaa catgtgcact tattaatatc ttgtgaccct
     2761 caatatggaa ttcataaagt agtaaaaggt ttaaaaggct ttagttcgag agtattaaga
     2821 gagaactttc cacatttaaa gtctagtatg cctagcatgt ggactaatag ctattttgta
     2881 ggtactgttg gttctgtgag tttagaagta gttaaacaat atatagaaaa tcaacaagtt
     2941 aggacaaaga aatgataaaa actcatagag tgaaattaaa cctaactaga acacaatttg
     3001 a
//
LOCUS       DAYAKB010000173         2982 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.178, whole genome shotgun sequence.
ACCESSION   DAYAKB010000173 DAYAKB010000000
VERSION     DAYAKB010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.178"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            73..771
                     /locus_tag="ACGI3L_003721"
     CDS             73..771
                     /locus_tag="ACGI3L_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9199400.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            complement(1352..1450)
                     /locus_tag="ACGI3L_003722"
     CDS             complement(1352..1450)
                     /locus_tag="ACGI3L_003722"
                     /inference="COORDINATES: protein motif:HMM:NF022636.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199401.1"
                     /translation="MFILKRLCKLVSINKSFSEEIPKNLKNTYMCI"
     gene            1794..2261
                     /locus_tag="ACGI3L_003723"
     CDS             1794..2261
                     /locus_tag="ACGI3L_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFG9199402.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            2272..2487
                     /locus_tag="ACGI3L_003724"
     CDS             2272..2487
                     /locus_tag="ACGI3L_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199403.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
BASE COUNT         1141 a          345 c          352 g         1144 t
ORIGIN      
        1 tatattacaa cattatttta tagtttgatt aatttaacaa tcactaatat atcaaactga
       61 aaggagattt ttatggaaaa aaaatatttc gaaattcatg gagttccttc aatcctttgg
      121 ggaaatcctt caagtaaatt atatatttac atacatggac aatgtggcaa taaagaggag
      181 gctgaagctt ttgctaatat tgcagttcca catgagtgtc aagttttaag tgttgatttg
      241 cctgaacatg gagaacgtaa aagagaaaaa aattcattta acccatggca tgttgttcca
      301 gaattagtat ctattatgga atatgcaaag tgccactgga atcaaatttc gttatatgca
      361 aatagcattg gagcatggtt tagtatgtta agctttgaaa aagagaactt aagagagtgt
      421 atttttgtat ctccaattct agatatgcaa cagctcattt caaatatgat gctttgggca
      481 aatgtatcag aagaacagct taaacatgaa ctaattatcc caacttcatt tgggcatact
      541 ctttcatggg aatatctaca atatgtaaaa caacatccta tcactcaatg gaatgtacca
      601 acaaaaatat tatatggtaa acatgatgaa cttactgaaa tcggtgttgt agagaaattt
      661 gtagaaaagt ttaattgcaa ccttactatt atagaaaatg gcaaacattg gtttaacaca
      721 ccacaagaat taaattcatt atatgaatgg ttaaatactt tagttaaata aaaaataatt
      781 atattattaa tatgattaaa ttatttataa atgttattta attaatttta ttttagcatt
      841 attaaaataa ctacataaag aataaattag ttattattaa agaaattaaa agtatataga
      901 gtattaataa ttttttaata attagttatt atagaaaaaa gagggatata atattgtctc
      961 cctctctttc ttctgtaata ttatataatt tttatttatc actctcaata aattatagtt
     1021 atctacaaaa ttcaatcttt aatacactat taatatattg tgatattaat attacagtat
     1081 taaataaaat ctaataaaat taactataaa atatctatta tataaatatc cactcttatg
     1141 tttgaaatcc gtcatatagt tttatccttc ttatctttta tatcaataac tttttttaat
     1201 aaaattgaca aaactaaagt aaaaaacctt attgataatg aaacaaatga tactataagt
     1261 tctgatatta tagtaattgc atataaatag acatcataaa aataatataa tattgtcact
     1321 ataaaattaa atgtaaaaat ctcaaatcta actaaataca catataggta ttttttaagt
     1381 ttttaggtat ttcttctgaa aatgatttat tgattgatac caatttacat aatcttttta
     1441 atataaacaa tgatacaata tatgggacag cacatatgta tatagctact tatattacat
     1501 attacagttg gcatattcgt atttgtaatg cttataccaa ttttaaaata caccatcagt
     1561 actaatggta ttaaaataat ctataataaa gttaaaatta ttccaattag tacaatatta
     1621 tttaatattt tacaactcat attctttttt atataaattt accaccttat acattcttat
     1681 ttttagtgta tattacaatg gttttatata ttatatcaat aatttattat tgaaattcaa
     1741 taaattgtat attataatca ataatatact ttatataaag gagatgatat tttatgatta
     1801 caaaattttt tagtaatata ttatcagtat ttctatattt tctattatca cttttaggag
     1861 ttgctggtat aatattctta tgtatgatac ctatgttttt atatgatttt agttctgaca
     1921 aagtaatcgc tttaattgca agaatactat atttttctga ctactttata gtcatcttat
     1981 tcttgatatt tataattaat agtactaagt attccccatt cgtacttgaa aatgtaaaaa
     2041 ggtttaaggt aatgggattt tgtttattga taaacactat aattgaatgt atcaatggtt
     2101 ataatttaaa tactaataat ataagaattt ttggaactga tagtggcggt atctcaccac
     2161 ttatgattat ctcttttata tttgcactaa tgtgctttgt aattgcagaa acatttgata
     2221 aagctataaa aataaaagaa gataatgatt taacgatata gaggtgatgt tatggcaata
     2281 gtagttaacc tagatgtaat gatggcaaaa aggaaaatat cacttaaaga tttggcagaa
     2341 aaaatagata ttacaaatgc aaatttatca attttaaaaa ctggaaaagc aaaagctatt
     2401 agatttacca ctctaaacga aatttgcaaa gctttagact gtcagccagg tgatatactt
     2461 gaatatgtag aagatgaaaa tgattaaaaa agagtgttta gaaacactct tttttattat
     2521 actatatgat ttttattctt ttactatatt attgacatta atattaactt tgtttaaagt
     2581 cataacaaaa tatgttctaa gaaagaaact gttcctttat ctatttgtta tccattacct
     2641 ataagaactg tatcacacta aataatactt ttaaattgat aattttacca cagattccta
     2701 tatacattct tttctaccta atatttattt aaactgttag caaaacatgg aactttttca
     2761 tttacttata cctccattta tattattgca tagtttatag ctacgtgtta taaattacat
     2821 tattgatgat tttatctaac atttgtaatc ttttagatac tctttgaagt tacaacactg
     2881 ttatactcta attaagtaaa ctaaatctga tacaagttgg tgattatatg aaaagaaaac
     2941 tttcaaccta ttttaaagga tatattttag gtttatgtat ag
//
LOCUS       DAYAKB010000174         2969 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.179, whole genome shotgun sequence.
ACCESSION   DAYAKB010000174 DAYAKB010000000
VERSION     DAYAKB010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.179"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            148..342
                     /locus_tag="ACGI3L_003725"
     CDS             148..342
                     /locus_tag="ACGI3L_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HFG9199404.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(444..953)
                     /gene="vanZ1"
                     /locus_tag="ACGI3L_003726"
     CDS             complement(444..953)
                     /gene="vanZ1"
                     /locus_tag="ACGI3L_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HFG9199405.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LIPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLVFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1273..1662)
                     /locus_tag="ACGI3L_003727"
     CDS             complement(1273..1662)
                     /locus_tag="ACGI3L_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9199406.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            2098..2373
                     /locus_tag="ACGI3L_003728"
     CDS             2098..2373
                     /locus_tag="ACGI3L_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199407.1"
                     /translation="MTLLELYYRKAEINKIVWARIGFNLYLSKGVALTLTDAGIGISG
                     LLAGAIPGIGQYLPLIVRLITMYLESNITSGKIFKFKKYVIIKEVLV"
     gene            2721..>2969
                     /locus_tag="ACGI3L_003729"
     CDS             2721..>2969
                     /locus_tag="ACGI3L_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199408.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIA"
BASE COUNT         1105 a          361 c          331 g         1172 t
ORIGIN      
        1 tattttaccc ataaccttta tttttttatt aaaatgcatt ataataaaaa gtaaatctaa
       61 atttgataca gttttaacaa tcattatttt cagaaaagtg atactattga atatattaag
      121 aataattaga gatggaggaa ctaagatatg agcgtaattg taatgtgtag tcgttgtgga
      181 aaagaaatag ataaatatag aaataaatat ataacttatt atgagaaaaa taccaatgca
      241 gaaattaaag tttgtataaa ttgtgcgtta gatttattag aaaaaacaag agaaaatcaa
      301 gaattgaaca tacaagagtt tcaagataca ataattcttt aataatttag gaaagcacct
      361 gtataggtgc tttttatgtg taaataattt tatatgtaac tgtatcttac gttctatttt
      421 aagctaaaca tatatactta tttctataag tttgcaaaaa taactaatcc taaaaataat
      481 acaacaataa ttgtcacaat caatgccaat acattgataa tttttatggt attattctta
      541 aatattttcg ataatagcat aaaaacagct attcctatga ttcctcctag tgtgtttcct
      601 atcaaatccg ttatatcact tgcacctagt gcaaatatat attgaagtgt ttcaaatacc
      661 aaactagtta taaaaatagg tataactttt tttataaagc tccattcttc ttttagcata
      721 cacacatata tcccaaatgg tacaaatata gccacattta atataatctc tgatatatct
      781 actctattat taattataag tgacccagca aaaggtatta agtttatgct tctaagattc
      841 atggtttcaa gagatgagat atcaaattgc aacttaaata gtattatcca tgttaaaata
      901 attatgtaaa ctataaataa tccttttgta atattatgtt ttctagattt catttattac
      961 ctccttacta tattattgta ttattttatt aatacaataa tatagtaagg taatttatct
     1021 gtcaactatt tcttctaaaa ttatattcct tttataattt caatatcttt atcatattta
     1081 catgatttaa gctattgtag tatttcatat atctttaaat tttaattggt attattctct
     1141 atatttttta ctatcaaaca ctaaggaaat aatcactttt ctttatataa tgttctacca
     1201 tcacataaaa ctaacattaa atccaaacgc tactctcaat tgtctcaaac taaaaagata
     1261 ctgatagctt tattagtcat caatatcttc ttctttcaaa tttttaaagt attcttctaa
     1321 tttgtccaag ctcttactat ctaaaacttc atcatcatgt agtgctgaaa taaaactctt
     1381 aaatgaattg ttatgcataa aactaaaaaa actctttgtc tcaactttta agtaatcttt
     1441 ctcttttata gctatagtat aatgcgtaca tctatctacc ttatcagtag ttaaaaagcc
     1501 cttatctact aaatttttta aaaatgtcaa tgttgtgctc tttttccaat cgtatttcaa
     1561 cttcatgtct tctatgatat ctcttgaggc taatacatca tctactcccc aaatatactt
     1621 cattagtttt agttctgcat gtggtaattt attaatcttc attagtttac acctcttacc
     1681 aatttatgta taactaaact ttataacaat aagtgtatgt aatcaattag attggaataa
     1741 atataaattc caatttattc tatataaaaa taattaataa aaaagaagta ctctacttta
     1801 gagagtactt ttggattata tattcaaaaa tttatctaac atgattagag tatgttttat
     1861 gctttagtgt gataatttta gttcgtttta ttattgcaac atgtattata tttcattata
     1921 atctataagc ttaaatacag gatatttatt tcatatactt aatttatatt aagttttatt
     1981 atatgtatta ttaagtttta ctatattttt tattaatatt taatatagtt aatttttaat
     2041 aattatatta tacaataaca atatataagc taattaaaaa ccttaagaag aacgatattg
     2101 acactacttg aattatatta tagaaaagct gaaataaata aaatagtttg ggctagaata
     2161 ggttttaatt tatatctttc taaaggagtt gcattaactt taactgatgc tggtataggg
     2221 atttcaggac ttttggctgg tgctattcct ggtataggac agtacttgcc acttatagtt
     2281 agattaatta caatgtacct tgagtcaaat ataacatctg gaaaaatctt taaatttaaa
     2341 aaatacgtta taataaagga ggtgcttgtg taaccaaata ctacttacaa tctgtagaaa
     2401 tcaataggtg ataaaatgat tataaaatat ctactttttg caattgtttc agcattaatt
     2461 ttattatttt gtaataaagc attccaacta agtaaattac acaagttcat tatattgttt
     2521 gtttcatttt ttatactaac ttttgtagca tcattcatta gtagataaaa aataagatgg
     2581 tggggttaac ttaccatctt tttctcattt aatatttgta atattttaga tactctttat
     2641 acttgtgtta ctgttatact ttgattagga aaattaatac aacatgagtt gatgattata
     2701 ttataaagga ggtatcttct atgaatttta ggaacattta tcttatactt atgggattgg
     2761 gaattataat attaactaca ataatatctt taattgaaat taaaattggt ttttgtaatg
     2821 aaaaatattt taataaatta gaatcaaaat atggaaatat agatagaaaa agaactatta
     2881 aactagaagt actttatcga tatgtaacag gttttgaata tatagcaata ggattattta
     2941 caaaaagatt agatattaca ataatagca
//
LOCUS       DAYAKB010000175         2834 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.181, whole genome shotgun sequence.
ACCESSION   DAYAKB010000175 DAYAKB010000000
VERSION     DAYAKB010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2834
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.181"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(1039..1254)
                     /locus_tag="ACGI3L_003730"
     CDS             complement(1039..1254)
                     /locus_tag="ACGI3L_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199409.1"
                     /translation="MHINQTGFISNELGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVRGGSSWAFNFIVQP"
     gene            complement(1437..1781)
                     /locus_tag="ACGI3L_003731"
     CDS             complement(1437..1781)
                     /locus_tag="ACGI3L_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199410.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            1908..2291
                     /locus_tag="ACGI3L_003732"
     CDS             1908..2291
                     /locus_tag="ACGI3L_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199411.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            complement(2651..>2834)
                     /locus_tag="ACGI3L_003733"
     CDS             complement(2651..>2834)
                     /locus_tag="ACGI3L_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199412.1"
                     /translation="YKNVLIYINIRTIIHINCKIKFIELYLTFNELKNKLANNEKTTV
                     INENNKVFSGLVDFSN"
BASE COUNT         1132 a          330 c          330 g         1042 t
ORIGIN      
        1 actataacag taatattata ttacttagtt agaaagagat atataactat ataaaatcta
       61 atagaattaa tatcaaaaga aggtagcaac taatcaccag caattaaaat aatttgtttt
      121 tcaaagttaa taaaagtctt ctttatagca atgatttaaa tataatcaaa tattgtaacg
      181 gagatttttt tatgaataat ttaagaaaac aattaatcaa agaaattata taagatggag
      241 aacttataaa atctacagat ataagtagtt ttaggagtaa acacagatga cttatttcaa
      301 agagacaata gctacaagtt atcctcattc tgtaatacaa aaatgtttaa tacattagat
      361 aagaaatact ttaaatatgt ttcatacaag gactcaaaag aattaataag taattttaaa
      421 tctgtatata ggtcagttaa tgaataagaa gccttatcga ctttagataa aatagattaa
      481 aaataatgta aacagtatac ttcagaaatt aaaattttgg gaaataactg gaatgttgta
      541 gcatcatcct ttagttttac taaaataagt aatatctata atatatatta caagtataat
      601 cgaaagattt aataaatatt tcaaaaatgt ctcaaaaaca aagtccagat ttacatcaaa
      661 cgcttcactc ttaaagatat tattcttgac aagcgaaaat gtgatgaaaa aatggactat
      721 gaaatataaa aattgatata atatatacaa tcatttattc atatcttttg atagtagaat
      781 ataattttaa aaattatacc ctaaaaattt gctataattg ttataatata tataatttcc
      841 aaaaatattt aaaaacatcc caatatacat tttttataat ttattaaaat aaaattcata
      901 tattaagaaa tattaatagt aaataagcaa ttgttactat aacataggaa ttatctttaa
      961 aaacacaaat taatttacat tctctaattt taaagtatat gtatatcttt gattttaata
     1021 aaattcactt aaaatatttt aaggttgaac aatgaaattg aatgcccaag aacttcctcc
     1081 tcttactaat gttgcaatta attcaaaccc acaattgtat tgaactgaat ctctacctac
     1141 tggtttccaa ctagaaggtg cattatatga gaaagaattt gatgttggct ctttcttttg
     1201 ttgctgctta attcctagct cattagaaat aaatccagtt tgatttatat gcacccttct
     1261 atttgttaca cgaatctggc cgtctgcaat agaccagttt ccagaaactt tactaacgga
     1321 aatatattga aatgctccat ctccttttga tattgtatat gtaactgtac cagatgcttt
     1381 tacaccacca gttttatccc atccatcttc tgatatactt gcttttctaa gaggctttat
     1441 tgtattagta tcaaaaaaac tgtcttagaa tatatctttg atgttaaatt tttagattgt
     1501 ttaacttcta ataattgagt tgttgatata gaatcaacgt atatggactc tcctgttctt
     1561 gcatttttga ttataccttt ttcattggaa cttttaacat cagtaattcc atttttagcc
     1621 atatcgtata atttgtccat gtctgttact tgtttctctg aatacattac tttcatagat
     1681 gaatcttcta ccttactagc acttgcattt gttggtaata gtattgtcat tatgagtaaa
     1741 gataaaatag ttgttacaga tttttttaac ctataattca tattaatcct tactttttat
     1801 ttgttataac agacattcta ttgtaataga atataaatcc acaatatttt taaaattagt
     1861 attgaataac tattctcatg ttataattat tcaaaggagg gattgatatg aggaaaaaat
     1921 tttttatagg tattcttata gttttaataa tctctgtgat agctatactt aatataaaaa
     1981 atgataaaaa tgtctttatt ggagaatcag aaaattggaa agctaaattt gtaactactg
     2041 aaggacactc aaaattagaa ataaaatata aaaatagtaa agatgtagtt gaacaaaaat
     2101 ttaattattc ctatcaattt atagatggtg aagatgcagt tgtagttgta aaaaatgaaa
     2161 ttttagaagc aggtcaagaa aaagcaataa aaatacaaag accaggtctt tattcaaata
     2221 gagaatctag ttacaagcta attatatctt ggaatggaaa tgaggaaact ataaacttga
     2281 aaaagaaata accatattat caatttttaa aaaattatta ttcaaattct tataaaaaga
     2341 gtgtttagaa agatgaaaca ctcttttttg tataagtttt tgaaaactat aaatgaaata
     2401 tatcaaaatc gttcgaaaaa ttactgaaat aaactcttaa atatattata aattaaggta
     2461 tattatacat gaatttattg ggagtttatg agttttaaaa ttggaaacca aacaataagg
     2521 gcgaaaaata cttcaaggaa aatatataaa gttctataaa ttatcaaaaa tatttcgcaa
     2581 aaattgataa ttattacaaa taaattgata atattagaaa tatcgaaatt gaacaaacta
     2641 ggattaaagc tcaattagaa aaatccacta atcctgaaaa tactttgtta ttctcattta
     2701 ttactgttgt tttttcatta tttgctaatt tatttttcag ttcattaaat gttaaatata
     2761 actctataaa cttaatttta cagttaatat gtattatagt tcttatattt atatatatta
     2821 atacattttt atat
//
LOCUS       DAYAKB010000176         2793 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.182, whole genome shotgun sequence.
ACCESSION   DAYAKB010000176 DAYAKB010000000
VERSION     DAYAKB010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.182"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..597
                     /locus_tag="ACGI3L_003734"
     CDS             <1..597
                     /locus_tag="ACGI3L_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199413.1"
                     /translation="GLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQS
                     LSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQ
                     YGDRLIMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            694..1731
                     /locus_tag="ACGI3L_003735"
     CDS             694..1731
                     /locus_tag="ACGI3L_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9199414.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            2540..>2793
                     /locus_tag="ACGI3L_003736"
     CDS             2540..>2793
                     /locus_tag="ACGI3L_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199415.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
BASE COUNT         1064 a          361 c          426 g          942 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaaatt actttagata gtactactat aacaaattta
       61 gctgagtata aaagaactca aatagtaagt agagtttttc aagacccaag ccttggaact
      121 tgtccttcta tgacggttag agaaaattta tctctagcac ttaataaagg gaaattattg
      181 aacttaaaaa aatgtcttcg tcataaaacg aatgacttgg aacacttact tgaaggaatt
      241 tctttggatt taaaaaaata tttagatatt aaagtacaat atctttcagg gggtcaaaga
      301 caatcactat cactaattat gtctagctta gcaagtccta aggtcttatt actagacgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa tagagttaac agataaaatc
      421 gtaagagaga aaaatataac tacacttatg gttactcaca acttgaaaca cgctcttcaa
      481 tatggagata ggttgataat gcttcataag ggtgaagttg tattagatgt aaaagataaa
      541 gaaaaaaaag atttaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtataagaa
      601 attaaaatct tagttttaat cagaaatatt tataatctat catatgaata tatgaacaaa
      661 tataattatt aaattttaag ggaggaaaat aaaatgataa aaagtaaaaa aatattaagt
      721 ttaattatag caggagtact tggtgtatca atgcttactg gatgttctca aaatgatggc
      781 tccaatgctt caaatgaaaa taaagaaaca gatagcaaaa aacaaaaaaa tataggtatt
      841 actcaattag tggaacatcc atctctggat aaagcaaaga aaggattcat caaagcactt
      901 gaagataaag gctataaaga tggagataat ataaaaatag atttccaaaa tgcacaaaat
      961 gatatgccta ctacacaaag tattgctagt aagtttgtat ccgacaaaaa agatttgata
     1021 tatgctatat ctactccatc tgcacaagca gcttataatg ctactaaaga tattccaata
     1081 ataatgactg ctgttacaga ccctgtagaa gctggacttg ttaaatctct tgaaaaacca
     1141 ggtggaaatg tttctggtac atctgattat ctttcaattg ataaaacatt agaattggtt
     1201 aaaacattga ctccaaaagc aaagaaaata ggggttatat acaatactag tgaagttaat
     1261 tcaaaaatcc aagttgattc tctacatgat tatgctaaga aaaataatta tgaagtagtt
     1321 gaaaaaggaa tcagctcttc aagtgaagtt aaccaagcta tttctagttt agttggtaaa
     1381 atagatgttt tatatgtccc tactgacaat ttaatagttt cttctatgcc aatagtttct
     1441 aaagttgcta atgaaaacaa gattcctata atagcctctg aagaaggttc tgtatcttct
     1501 ggtgctttag cttgttgtgg aatagattat gaaaaactag gttataaggc tggagaactt
     1561 gctattgaag tattagaagg aaaatctgtt ggcgatatac cagttactac attagatgaa
     1621 actgaaataa taattaacga agatacacta aaagcacttg acatgcaaaa gttatcagca
     1681 gataatataa agtatataaa gtcagatgaa aatgcaaaat ctacaaaata aaacttatta
     1741 atttcaaaaa ataggtaata tgaagtaggt aatatgaaaa ctttatataa taagtactct
     1801 tatccaccct aaccctttga aaattgtgct tattgtagca atttgaatat tgcatataaa
     1861 gttattcatt ttccataaaa gtcgtctata ttgacgactg attatgaaag ttatataact
     1921 ttctaatcac tacttgagct gtccaaaaga attttaatat tctccagaca gctttttttt
     1981 atgatatttg attgatatac atgtctagtt attccatatt tagtaaatat tttgataaaa
     2041 tttccacatt cacttataac ttaggataac gtttttttca aacaatacat taatttaaaa
     2101 gtattctgag tatacattat ttagtatttt aattaaattt agcagttgac ttttattatt
     2161 gtataattta taatttataa caagtcgaga atacatataa ttttctgact aattaaaata
     2221 ttaaaaggga gagataatta tgaatacttt attaaacaat agaaaatatt attattatta
     2281 tagccactat ttttagggtt tgtacctacg ttttaacata gatacagacc ccttaagact
     2341 actaaaattt tgggattgta tctatgttgg ctatattgtt tataaagttt tcatctaact
     2401 atataagagc cacatagatt aaactatgtg gcttattcgt gtttttacca catagttttg
     2461 tacactatgt ggttttttta tacacaaaat tagcaaataa ttaaaattat aaaaatattt
     2521 tcaaaggagt gttttattta tgtcaggtat tatatctgta atgacgcaaa gtttaatttt
     2581 atcgattatg gcactggggg tttatataac ttacaaaatc ttagattttc cagatatgtc
     2641 tgctgatggt agctacacaa tgggtgcttc tattgtagca ttttctctta ctaatggtat
     2701 ttctcctgta gtagcaactt taatggctat cttatgtggt tgtactgctg gtcttgttac
     2761 agggattctt cacattaagt ttaagatatc taa
//
LOCUS       DAYAKB010000177         2778 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.183, whole genome shotgun sequence.
ACCESSION   DAYAKB010000177 DAYAKB010000000
VERSION     DAYAKB010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.183"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            423..1184
                     /locus_tag="ACGI3L_003737"
     CDS             423..1184
                     /locus_tag="ACGI3L_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HFG9199416.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            1249..2031
                     /locus_tag="ACGI3L_003738"
     CDS             1249..2031
                     /locus_tag="ACGI3L_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFG9199417.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKCKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            2298..2717
                     /locus_tag="ACGI3L_003739"
     CDS             2298..2717
                     /locus_tag="ACGI3L_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HFG9199418.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
BASE COUNT         1111 a          276 c          499 g          892 t
ORIGIN      
        1 catattaggc aatagggaat ttttttatag ttaaattttc aaatattttt tagggaactt
       61 tataattgag aattaagggt atagtatgtg atgaacttac taaatttata attaggttat
      121 ataatggaat aatcatcaat agttttactt tagggaaaat atatgcttaa ggaagtatag
      181 cttactaata ttattaaaat gtatatttaa aatgataaaa aaagaattag acaagtattt
      241 agtaaattga ctatgcaaaa ttctatcaag caggaacact atgactttag tcatgggagg
      301 ttcagtaggt aacttgttga attaagttta tattatttaa ataaactact taatttagat
      361 aatataaaaa gtcagaattt taagaataga gctatataat cttagctatt aggagaagta
      421 ctatgatagg aatatatttt agtggaacag gaaattcaag atactgtgta gaaaaatttt
      481 tacaagaata tgatataaca gcaaattctt attctattga agataatgaa cttttacagc
      541 acatcaataa tcatgagaat attattttta gttatcctgt gcaatatagt aatgtgccaa
      601 aaatattgaa agattttata ataaatcatt caactttgtg gaatggtaaa cgtgttttta
      661 ttattgcaac tatggctcta tttagtggag atggctctgg tgtgttagct agaatattaa
      721 aaaaatacgg tgctataact gttggtggat tacatgtgaa gatgccagat agtataggag
      781 atgaaaaggt attaaaacat tctttagagt ataatagaaa gcttgtaata aaagcagaaa
      841 agaaagtaac taaagctgct aaaaaactga aacatgggtc accaccaaaa gaagggttgg
      901 gttttttgag tcatattgta gggttatttg gacaacgatt gtattttatc aataaaacaa
      961 atatgtatac agataaacta aaaattaata ctgaggaatg tattgtatgt ggtaaatgcg
     1021 ttaatttatg tccaatgaag aatctagtaa ttaaaaattg tatgattgtt gcaaatgggc
     1081 aatgtacaat gtgttatcgt tgtgtaaata attgtgccaa aaaagcaatt acattgttag
     1141 gtaaaaaagt tgttgaacag agtaatatta aaaaatatat gtaagaaatt taaagtttta
     1201 ttgaatgtaa attgatgtat attttatgtt agaaagagag gttaaataat ggaatactac
     1261 atagttgatt catttgcaac taaactattt aaaggaaatc ctgctggagt ttgtgttctt
     1321 gacagaagaa tacctttaga gttaatgcag aaaatagcag aagaaaacaa tttaccagaa
     1381 acagcatttg tagttaaatg taaaggaaat tatgaattac gatggtttac tcctaaagca
     1441 gaaattgatt tatgtggtca tgcaacttta gcagcagctt atgtaatatc aaattttatt
     1501 gatgttaatg taaaaaggat agatttcttt actcaaagtg gaaagcttga agttacacga
     1561 aatggaaatc tatatgaaat gatatttcca gaaataatgc ctattgaaat agagttatca
     1621 ccacaacaag ctaatttgat aggctgtgta ccaagtgctg tttattcttc aagagattta
     1681 atcttattgc taaacagtga acaagaagtt ataaattata aacctaatta cgcacaattg
     1741 cgtaaattga cagactggtt aggtataata atcacagcac aaggaagtaa tacagatttt
     1801 gtatcaagat atttttgtcc agaattagat tcagaagacc ctgttactgg ttcatcacat
     1861 tgtaatctta ttccatactg gtctgaaaag ttgggaaaac acaaaatggt agctgctcaa
     1921 ctttctaatc gtggtggtat aattcagtgt gaagtgttga aggataatac tgtaaaaatt
     1981 tctggtgaag cagtcttgtt tatgcaggga acaataaaga ttgatattta aataagtata
     2041 ataactaatt tattatgaaa aataattaat tttcttagtg ttaacaataa taaagtagag
     2101 ttaaaaagct tgatttcact taaatcaata tgatagatgt tgatactaag attgacaagc
     2161 atgattaaaa aagataatat ttaatctata aagataaaaa cacagtctgg ttggtagtcc
     2221 agacgcagca atagctgtca gtaacctgcc tccttggttg tccgttcttt agaaagtaat
     2281 ttaaggagga actagcaatg gacaaaatta gtggaaaatt aacagtttta tttgaagaac
     2341 cattttgggt aggtatattt gaaagacaag atggtaaaaa atatgaagca tgtagggtag
     2401 tttttggagc agaacctaaa gaagtagaag tgtatgaatt tatacttgaa agatttttct
     2461 cattagattt tggtagcatt aaattagaaa aaaatgtgac caaagacaac attggataca
     2521 aaagaatgca gagaaaagta aaaaaggaac aagaaaaaga aactataggg actaaggctc
     2581 aaaatgctct taagcttcaa tatgaagaaa gaaaacagga tagaaaaaac ctagctaaaa
     2641 atagaaaaga agaagaaaaa gaaagactat ttaatttgaa acaagaaaag agaaaagcta
     2701 aacataaggg tcattaattt taattaaata tctttttaat aattgctaga aaaaggtgta
     2761 taaaattttt aattttat
//
LOCUS       DAYAKB010000178         2641 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.184, whole genome shotgun sequence.
ACCESSION   DAYAKB010000178 DAYAKB010000000
VERSION     DAYAKB010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2641
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.184"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            402..1703
                     /locus_tag="ACGI3L_003740"
     CDS             402..1703
                     /locus_tag="ACGI3L_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFG9199419.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1779..2054
                     /locus_tag="ACGI3L_003741"
     CDS             1779..2054
                     /locus_tag="ACGI3L_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFG9199420.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGETYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
BASE COUNT         1092 a          212 c          513 g          824 t
ORIGIN      
        1 tattactatc aggtagtgaa ttatattgaa cgatatatta ataattggca gtaaattata
       61 ttaaataaga tattaatatc gagtaatgaa ttatattgaa cgatatatca ataattggca
      121 gtaagttata tcaaataaga tattactatc gagtaatgaa ttatattgaa caatatatta
      181 ataattggca gtaagttata tcaaataaga tattgctatt atgtagtaaa ttatataaaa
      241 caatgtatca gaataaatag tatattaata atttgtagta tatcatgacg aataatacag
      301 tcataacaaa tagtgagtca taacaaataa tgtatttata attgataatg tatttaaaaa
      361 tcaaaatata aaaacttata aggaaagaga gattaattta tatgggtaaa tcaaaagatg
      421 ttgaaataga gaagtctatt ttaggcacaa ttcttttaga caataaatta agctataagc
      481 tagatgaatt aaatgaaaac atgtttatga atgatatatg tcttgagata tttaaaatta
      541 tgaaagaact taaaaaagaa aacatagtga ttgatgtggc cactgtgaaa tcaaagatag
      601 atagaaaatc tctagcaata aaaacaagtg atgtgactaa tctaattact tggggtcaga
      661 attttggtct tgatggtcat attaaaattt taaaagaaaa tttagctaga agaagcataa
      721 atcaaaactg ccaaaacctt ttacacagcc taaaccttgg agaaaatatc gatacttgta
      781 tttacaaatt tgaaagtaat ataaaggaga ttttggacaa ggatacttat gaaaatgatg
      841 atgtaaatag tatagcaggg aaggtgcttg attttttaga aaacaaaaaa gatattggat
      901 ttaaatttgg tataaaatta cttgatacca ctataggagg tctttttaaa ggagagctaa
      961 ccacaatagc agctaaatcg ggggttggga agactgcttt ggcacttcaa ataatgttaa
     1021 attcatttaa gcaaggtaaa aaaactttat ttataagtag agaaatgacc agtgagcaag
     1081 tatttatgag aaatatatgc agagtaactg gtgtaagtac aaggaatatg aaatctaaag
     1141 aaatagatga aaatgattgg aaacttattg taaatgcgat aggtgattta agcgaaaata
     1201 acttaattta tatcaatgat aagatagata caattagtgc aattagaaag aggataaggc
     1261 aggtaaagcc agatttatta atagtggatt atgtgcaact ccttacatct cagaaaagca
     1321 tggataagag agaaagggag gtagctactt tttcgagaga acttaaaaat atgactttag
     1381 attttaatat acctgtaatc caattaagtc agttaaatga tgaaatgaaa gattcaagac
     1441 cttatggaga tagacctatg agggatagca aagccatcta ccacgatagc aacaatgtgg
     1501 tttatataca tcaattaaag gggagtgatt atgaagaagc agtgagagat attggagaaa
     1561 gtgaggaggc agttagagca tcagaataca ggggaattaa gatggttgat ttaatagttg
     1621 cgaagtgtag agatggacag actaggcata agcatttttg ttactttggg gataagttac
     1681 attttcaaga actaaattat taggtcaata aagtagtaat aacaagctta ttaaaagtcg
     1741 ggaaatagca aatagattat aaaatatgag gtgaaaatat gttggaatta agaaaaatta
     1801 tagaattact tgaagaacac aagatagaag taagtattcc aaaggagtta cataagtata
     1861 gtttattgga ataccttgaa ttgtgtcaac aaagtgggga aacatatttt tatattaaaa
     1921 cactggaagg ggctttaaaa gaggctagaa atgagcttat gattaaattg tttaatggga
     1981 aaaattatat ggaattagcg aggatgtttg aaatgagtgt tattaatgtc aggcatattg
     2041 ttagaaaaaa atagatattt ttggagaata caagtgtgat atacttctga aatagaagtt
     2101 attataagag gagtataagt gtgattaaca acatgatttt gtgaataaaa ttgaggatat
     2161 atatgagtta aatgtgtgat taataaggta agattgtgta taagattatg agtatttaaa
     2221 aggaggggct ataattaata gtgtagagtt gtgtgtttgc ttaagattat ataataattt
     2281 aatagattaa actatactaa taaggtaaaa tcgtgtgttt agttaaagct tattataaaa
     2341 tcttgatatg tgattaatga tgcaatatgt gaataaagtt aagattataa tagatttaac
     2401 ctgtggctaa tagaataaaa ttgtgaataa agttaagatt ataataggtt taaattgtga
     2461 ctaatagagt aagagtgtaa atagagataa acttcaatat gagcttaacc tatgattaat
     2521 agagtaagaa tgtaaataga gataaacttc aatatgagtt taacttgtgg ctaatagagt
     2581 aagagtgtaa atagagataa acttcaatat gggtttaact tgtggttaat agagtaaggt
     2641 g
//
LOCUS       DAYAKB010000179         2517 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.185, whole genome shotgun sequence.
ACCESSION   DAYAKB010000179 DAYAKB010000000
VERSION     DAYAKB010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2517
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.185"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(174..899)
                     /locus_tag="ACGI3L_003742"
     CDS             complement(174..899)
                     /locus_tag="ACGI3L_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199421.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEDEEYEEELKQN
                     IIENIKKNFDEKNLVQVYKYRGV"
     gene            complement(883..1245)
                     /locus_tag="ACGI3L_003743"
     CDS             complement(883..1245)
                     /locus_tag="ACGI3L_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199422.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            1812..2204
                     /locus_tag="ACGI3L_003744"
     CDS             1812..2204
                     /locus_tag="ACGI3L_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9199423.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
BASE COUNT          904 a          389 c          199 g         1025 t
ORIGIN      
        1 taaacatatt aattcgccta acatacctta tatctgaaca aagttgacgt gcaaataaat
       61 ttattttatg attttcaaga ttatcttttg gaaaagataa tgtaactatc aagagtatta
      121 tactgataga tactattaat tctattacag tcacattcct tcttttttca aagttataca
      181 cccctatact tatatacctg tactaggttt ttttcatcaa aattcttctt tatattttca
      241 attatgtttt gtttaagttc ttcttcatat tcttcatctt cttcatcttc ttctgtaaat
      301 ccaccaacct cttgattcct tatattttca ctttcatttt taaattgatt tagaatttca
      361 ttattttcag atgctttata attattgaat gttttgtcat caattttatt gttattagat
      421 ttatccatat aatcttcaat gtcaattcct atccatggat ttttgatttt cactcttact
      481 tttattgctt ttaaaaattc tttttctcta acattacttt ctatatcaaa ttcaaaaaaa
      541 tctcctctgt cataaatagt attattttct acttttaaag aaagttcttc taaactacta
      601 taagatgtat cttttatttt ttttatacat tcaatcatat tatttcctaa gaaatattct
      661 ctaaattcgt cttcattatt agatacatca atagcttcct caacacaaga aagtacatta
      721 cttactgata tttctattcc acttaaagaa atttctttta gttgaatgtc cttgtatcct
      781 aactcaaaca tattattatg tgtataaatt aaacctatac acataatgca cacagtactt
      841 ataatagaaa atattatcaa tgttattatt aatatagagc ctttattttc tagtaacata
      901 gctattaaac ctcagttttt taaattcatt ttttatctct atatttattt catagcattg
      961 ataataatct aaaatttgct ctattttact gttaatttca tatccattta tgtaattttt
     1021 ttctatctta tcttcaatta actcatactt actattttgt attctatact tctcatcttc
     1081 tatatatttt tttgctgtac ttaacatttc tctgtcagat atatttctac tgataaaact
     1141 ataacaatta tacaatgatg tagaaactaa ataaacagcc acatataata tagcaatact
     1201 tattatacat tcaattgata taaaaccact ctttcttatt ttcaataata aaaacaaccc
     1261 ctaaataata ttttatatat aaacatttaa ctataagttt tttcataaat atcttttgta
     1321 agttttttca ttgtaatcaa aatttcttcc catacatata taaattaaca caccaccttc
     1381 acccttaaca gtattaacta tgactgatac ttttgcttgt aatcaacttt atacaaacaa
     1441 ttaattacat ttactttttt aagtattgta aaattacacc tcctatattc atatttttat
     1501 agactctaat gctttgcatt aatcttttac ttcaacacca aaacatatat aaatactatt
     1561 tccttttata tttattgaca cctcaattcc aatttatact ttataaatca ataatttctt
     1621 cgccttattt catatatata caacaaaaac ttaaatttaa attcccactc tttatgtcat
     1681 attccattca aaagtttgca aatatatgtt ttaaattcta aaaatatgca tattatttta
     1741 ttagataaca gtcaacttgg ataagtctcc ttcatataat ttaaagtgac cgttgaaaag
     1801 ggggtgacct attggcagct cttaaatctt ttgaaaaacc cttaacccct gaagaagaga
     1861 ttgagtattt aactaaattt aaaatagaaa acgataaaag tgcaaaagat acattaattg
     1921 aaagaaacat gagattagta gcttatatag caaagaaata taataattca acggaagatc
     1981 aggatgattt aatatccata ggtacaatag gattaattaa agctatagaa acttataaca
     2041 tagataaagg aactcgatta gcaacatatg cttctagatg tattgaaaat gagattttaa
     2101 tgaatattag atctaacaaa aaaaataaaa ctcaagtatc tctacaagac cctatcggaa
     2161 cagataaaga aggtaatgaa ataaacacta ctctttatat gtaattttct actattatat
     2221 atttatttac tctataaaat aatccccatt caaaacactt ttcttaaatc actcaaacta
     2281 aaatacatat aagattatca ttagtcagta agtatatatt tttctaattt ctaaaaatac
     2341 atccaaatca tcaaacgttt ttagcaatta ctttattatt atacagtgtt aaagtaaagt
     2401 tcctaaataa attgttattc atatagcaaa taaatacttg gtatcaattt tttaatatct
     2461 atttaaatag tattttttat tttgtcactt tatagatatt aatgtgtatt taacact
//
LOCUS       DAYAKB010000180         2512 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.186, whole genome shotgun sequence.
ACCESSION   DAYAKB010000180 DAYAKB010000000
VERSION     DAYAKB010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2512
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.186"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(40..942)
                     /locus_tag="ACGI3L_003745"
     CDS             complement(40..942)
                     /locus_tag="ACGI3L_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9199424.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSEGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(992..1453)
                     /locus_tag="ACGI3L_003746"
     CDS             complement(992..1453)
                     /locus_tag="ACGI3L_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HFG9199425.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(1505..1960)
                     /gene="def"
                     /locus_tag="ACGI3L_003747"
     CDS             complement(1505..1960)
                     /gene="def"
                     /locus_tag="ACGI3L_003747"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFG9199426.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(1932..2195)
                     /locus_tag="ACGI3L_003748"
     CDS             complement(1932..2195)
                     /locus_tag="ACGI3L_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9199427.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(2292..>2512)
                     /locus_tag="ACGI3L_003749"
     CDS             complement(2292..>2512)
                     /locus_tag="ACGI3L_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199428.1"
                     /translation="MVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDN
                     YVYMFISIVISLIWILLLFKKFSKKIVK"
BASE COUNT          823 a          423 c          222 g         1044 t
ORIGIN      
        1 ttttaatcat catagtaaaa aaaatttttt tatataaaac taatcaaaaa aagatatctg
       61 tacatctcct gagtttttta acttttcctt cattatttta gagtaactgc ttgatagaga
      121 atatttatat ctaagttcat taaccatttt atacaattga tttttatact ccctattaag
      181 tgaaccttca ctatatagta ttgataattt atcaaataat tcaggaaact cttttttaac
      241 aaagtcaaaa aaaacacctc tagttatacc ccttaagtat aaagtcccag gtaaaacata
      301 atgtacatta cattcttttg catgtctaaa tagcgaattt atattatcaa aatcatctgt
      361 aatatatggt ataattggca taatatgtag accaactgat gcgttagttt ttctaaattc
      421 ttttaacatt ttaaatcgtc tcattgaatc cacaccattt ggctcaataa gcctttgtgt
      481 atcttcattt actgtggtaa ttgtagatgc tacattgata tatgtaatcc tagatagctt
      541 atcaattaaa tcgtaatctc ttaaaattaa atctgacttt gtagaaataa tagctggtgt
      601 cttgtatttt attagcaggt ttaatatttc tggcataatt ttatagtcag cttctattgg
      661 ttgataacta tctgtaactc ctcctatatt gattacttct ttcttccatt tactgctttt
      721 aagttgtctc tcaagttttt ctactatatt tgtttttaca taaatctctt caaaataatt
      781 attggagttg atgtacttat gagagtaaat agcataacaa tatttacatc catgctcaca
      841 tccacgataa atatttaaat cccatttata tggcatactc ctttttaatt tattacaagc
      901 tatttcacaa tttattggaa tatattttat tttattatac aaataatcac ctctttatat
      961 acaataatac tataatgtta atctatagta attaaaacat gatatttcca gaccacaatt
     1021 cataatcttt actatattta caaagtaata tattccattc atttattggt attcctccac
     1081 atgttgcttt ttcttctaaa ttatataagc attgctttaa atacatttta ttatgccaat
     1141 catcatataa attttctaaa tttaaactat gttcattaga tatatcattt gcaaaatttc
     1201 tatttttcca ttttaatata cttgtatatt taagttcatt aggtttataa tttcttttta
     1261 acatttcatc atgtacaatt tttgtataaa atttaaattc atctatacta taattcaata
     1321 ctttattcac taatagatgg tttggagtac cttttttatc tatagaacct tttatagcaa
     1381 gtagctctct ccattgactt actaattgat ttttaggtaa tacatcaatt aaatccttat
     1441 gccataatct cataatttaa ctccttacta taaaatattt tataaattca ataaccaatc
     1501 tatcttacaa ttttacatgt tcaataattt tatctgtaaa aactatacca tttaaatggt
     1561 ctatctcatg acaaagacat tttgccataa aacctgaacc tttaatttct attttctcac
     1621 cgtattcgtt tagagcttgc actgtaactt tttttggtct ttttaattta ccccatactt
     1681 caggaaaact taaacatcct tcaacaacaa tttgttcccc ttcttgttta ataatttcag
     1741 gattaacaag cttaataagt ccttctccta aatctataac aactaatcgc tttaatactc
     1801 ctacttggca tgcagctaat cctcctccat ttggagtatt gtacatggtc tctgccatgt
     1861 catttaatat ttctcttatc ttattatcta cgttttctac atacttactc ttttttctta
     1921 aaatttcatc atcaaatgtt cttatctttc ttatagccat aatattctcc cctacttatc
     1981 tgtgctcttg attttctttc actttcttca aataaaaata cactttcaat tggttcatta
     2041 aaaattcttg aaatatcata tgccaaccat attgaaggtt catttttacc agtttctata
     2101 gcatttatag cctgtctaga tgttccaact aatctcccta gttgttcttg tgtcaatcct
     2161 aatttttctc ttaatatctt tattttattt ttcatatttg ctccattcat gtaaggttaa
     2221 ctttacatct taaatgtaac atttttcaac attactgtca agtcaacctt acatttatat
     2281 attaaatttt cttatttaac tattttttta ctaaactttt taaataataa taaaatccat
     2341 attaatgata taacaattga aataaacata tagacataat tatcttcctt aaatgccttc
     2401 gatatccaaa aagttggtaa gaagaacaga atatattgtg ctttatttaa aataaaaaat
     2461 ggtgctaaaa tacccatcat aaaaacacct gagaatttcg taattaccat tc
//
LOCUS       DAYAKB010000181         2400 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.187, whole genome shotgun sequence.
ACCESSION   DAYAKB010000181 DAYAKB010000000
VERSION     DAYAKB010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.187"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(101..304)
                     /locus_tag="ACGI3L_003750"
     CDS             complement(101..304)
                     /locus_tag="ACGI3L_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199429.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            complement(1006..1296)
                     /gene="cas2"
                     /locus_tag="ACGI3L_003751"
     CDS             complement(1006..1296)
                     /gene="cas2"
                     /locus_tag="ACGI3L_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HFG9199430.1"
                     /translation="MKKKNNLNYNYVFVVYDVGEKRVSKVFKVCKKYLSHFQKSVFRG
                     EITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEEEILGNNSNCENMIL"
     gene            complement(1507..>2400)
                     /gene="cas1b"
                     /locus_tag="ACGI3L_003752"
     CDS             complement(1507..>2400)
                     /gene="cas1b"
                     /locus_tag="ACGI3L_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1b"
                     /protein_id="HFG9199431.1"
                     /translation="TSEIFCLNEVSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKE
                     YLISGKVTVAQVKTFEDRREEIAKSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKK
                     DSINKLEKSNNIKEILSVEGDIWQTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISF
                     GNSILYAKTVTAIYNTHLNQSVSFLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNN
                     RKINIEKHFDKNLNYCVLNDEGKQIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAY
                     KMLKCIMEEKSFIPYNIKDGL"
BASE COUNT          864 a          319 c          204 g         1013 t
ORIGIN      
        1 atttttacta ttcatagaaa tttcatatat tattccacag attaaaatta atctattatt
       61 ttttgtattt tgtggaatat tataaaatat tctagtatta ttaaatgccc ttttttattt
      121 ccacaacatc ttctatttta cagtctagtg ctaaacatat cttctccatt gtatccatag
      181 aaacagattt atcatttcct agtctgccta aaacagaaat acttatacct gatatattta
      241 caaattccat tttctttatt tttctgtcaa ttaacaattt ccataatgga gcgtatgaaa
      301 tcatgttatc acctcgcaaa atatattcta tcacatttta tctattttgg aaaattttca
      361 tctatttaga taaataatca cctgcttaag tgtcaaataa ttttatcctt ctaatatgaa
      421 aatttaatac tatactaaat gattggtata taacacatat gatgcattat tattaacata
      481 taaaaatttt tattggtgct aaattaaagt aatatactat tattatattt gcagatatat
      541 aagaaagatt ttattatata tttaaagtac ttgattataa taagagacaa gggctatgat
      601 ggatactata gaaagttaga actatactat tttagaatga acaattaaaa taattaaaat
      661 tagtttaatc ttttattctt gataaaatca tattaaataa atacaaaaag aatcttatta
      721 ttagaaatac tgaataatta taatgaaaat tataatatat atagacttgt gtaaatatat
      781 tattacctag tattaataaa attttcccat tataatagta tttcttcatt atagaaaaat
      841 gctattgata atgttttgta cactaatgtt aacagttata cataacaaaa atactgcaag
      901 taaatccttt tcacaaaaat ctacttgcag tctctatcat aaattatatc ccaattttac
      961 tactctttaa taagctatta ttttttacaa atatagtaat tagatttata atatcatatt
     1021 ttcacaatta ctattattcc ctaatatttc ttcttcaaat gtattagaat tcatcaactt
     1081 tattatacat acaaaatcat tatctttatc tataatattt tctaaatcac gttttaagct
     1141 cataatctta gatggagtta tttcacctct aaaaactgat ttttgaaaat gcgagagata
     1201 ttttttacac actttaaaaa ctttacttac tcttttttct cctacatcat agactacaaa
     1261 tacataatta taatttaaat tgtttttctt tttcatatgt aatataatat ttaaactgaa
     1321 aaatatacaa aaccttggca aattataata gaataattat ttttcagtat tttctccttt
     1381 ctcatcttaa aatacttcta aaaacttata ttatttcaat aatatattat gtatacttat
     1441 aatagcataa ttatcattct tatatatatc aaagttctat attaaaatac ttactttatg
     1501 tttaaattat aatccgtctt ttatgttata tggaataaaa cttttttctt ccattataca
     1561 ctttaacatt ttgtaagcat ctaattttat acaggttttt aaacttactt ttcgttttaa
     1621 ttttggatgt tctttgactg attctaatct ttcttctaaa gaatttataa aaatttgctt
     1681 tccttcatca tttagaacac agtagttcaa atttttatca aaatgttttt caatatttat
     1741 ttttctatta ttaactaaat caaatatagt tttaaaagtt ataacatgtt taaaattttc
     1801 acttaaatct agacttaaag aaaatctact ttcacttggt tcatgtaaaa aacttacact
     1861 ttgatttaga tgtgtattat atatagcagt tacagtttta gcatataaaa tactgttacc
     1921 aaatgatatc attgcgttta agggattatc tggtggtctc ttaactcttt tattaaaaat
     1981 aaattcctct cttaaaatat acttaaagga agtataaaat gtttgccaaa tatctccttc
     2041 gactgataat atttctttta tattatttga tttttctaac ttgtttatag aatctttttt
     2101 tagatgtgat aataatggtt gtatttctga atttccatgc ttatagtaat gcgataatgt
     2161 atttattgca ttaatcctta taccattgac tatggatttt gctatttctt ctcttctatc
     2221 ttcaaaggtt tttacctgtg ccactgttac ttttccactt attaaatatt ctttaggata
     2281 aaaagttcca ctatatccac catagtaatt aaaaaaatga acaacaatat ttgctcttga
     2341 taaaaaatcc agtaattttg aatttaaaga tacctcattt agacagaata tttcactagt
//
LOCUS       DAYAKB010000182         2334 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.188, whole genome shotgun sequence.
ACCESSION   DAYAKB010000182 DAYAKB010000000
VERSION     DAYAKB010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.188"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            171..2243
                     /gene="ptsG"
                     /locus_tag="ACGI3L_003753"
     CDS             171..2243
                     /gene="ptsG"
                     /locus_tag="ACGI3L_003753"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005355 - glucose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1904659 - glucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-specific PTS transporter subunit IIBC"
                     /protein_id="HFG9199432.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENTLVEKIDSLTNGELLDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT          858 a          252 c          447 g          777 t
ORIGIN      
        1 gtttataaaa aaattataat agtttatttt taattctgaa attaggttaa tataggtttg
       61 tttatattaa cataagttta attttagaat taagtatact aatgtaactt tttataaact
      121 taagtctttt ttatttaaaa aaatataaaa taataaggag agaaaagtaa atgaaaaaag
      181 tatttggtgt tttacaaaaa gtaggaaaat ctctaatgct accagttgca ttacttcctg
      241 cagcaggtat attacttggc gtgagtaatg ctttagcagg agacgcattg ttggctcatt
      301 ttccagcttt ggcgaatcct acatttcaac ttataataag tataatggaa agttcaggtc
      361 aaattatatt taataactta ccacttatat ttgcagttgg ggtagctgtt ggtttaactg
      421 aaggagaagg tgttgcagca ttggcagcca tagtaggttt tttaattctc aatacatcta
      481 tgggtgttat ggcaggtgtt acagaagata tggtagacaa ttctatgtat gcaaatattg
      541 ttggaatacc aacaattcaa acaggggtat ttggtggtat tattataggg atagtggctg
      601 cttatcttta taaaaagttt tataaaattg aattacctca gtatctaggt ttttttgcag
      661 gtaaaagatt tgtaccaatc gttacttcat tagttgctat agcaatagga attatattgt
      721 cttttatttg gcctccaata caagagggat tacttagttt ctcaaaaaat gttatagaag
      781 caaatcaaac actagcagca tttatggaag gttctttgga aagactatta ataccatttg
      841 gtttgcatca tgttttccat aatccatttt ggtatcaatt tggagaatat gtaaataaag
      901 ctggtgagct tgtaatgggt gaccaaaaga tattctttgc tcaacttaaa gatggagtaa
      961 atttcacagc aggtactttt atgacaggtg catttccatt tatgatgttt ggtcttccag
     1021 cagcagctct tgctatggtg catgaagcaa agccagaaaa gaaaaaattt gtagcaggta
     1081 taatggcatc agcagcatta acctcttttt taacaggaat aaccgagcca atagagtttg
     1141 cgtttttatt tgttgcacca gtattatttg caatacattg tttattttca ggtttatcat
     1201 acgcaattat gcaattatta ggagttaaaa ttggattcac attttcagga ggattaatag
     1261 atttcttatt atttggtgtt cttcctaata gaactccatg gtacttggct atcttggtag
     1321 gtattggttt tgcagtatta tactatagtg tatttagatt tatgataaga aaatttaatt
     1381 taaagacacc aggaagagaa gatgagtcag aaactaacgc tgaagtcatt gaaatgtcta
     1441 agaatgaatt agcatcagag attttgattg ctttaggaaa taaagacaac ttaaagagtc
     1501 tagatgcgtg tataacaaga cttagattgg ttgtaaatga tataaataaa gtagataaag
     1561 aaaaattgaa atcacttgga gcagcaggtg ttatggttat tggcaacaat gttcaagcta
     1621 tatttggacc aaaatcagat tcaataaagt ctgatataaa agatataata gagggaaaaa
     1681 caaaggttga aagtactgtt actaaaaatg ttgataaaaa taaagtgaaa aaaaatatgg
     1741 aagttgcaaa tatggaaaat actttagtag aaaagattga ttcattaaca aatggagagt
     1801 tattagatat agaagaagtg ccagattctg tattttcaag taaactgatg ggggatggat
     1861 ttgcaattaa atctagtgat ggattgattt attcaccagt tgatggaact attggagtta
     1921 tatttccaac taagcatgca ataataataa aatcccaaaa aagtggagta gaaatactta
     1981 tacatttagg gatagaaact gtaaacttag aaggaaatgg atttgaagta tttgtgaatg
     2041 taggagatga agtaaaagcg ggagaaaaat tagttaaaat ggacttagaa tatattgaaa
     2101 aaaatggtct atcaacaata agtcctgtag tatttacgaa tttagaacaa aatcagaaat
     2161 taagcattaa aaaaggagta accacagcaa aagaggagaa tagagtaagt atattaagag
     2221 atgatattga aaaaatagga tagctatatg atagtgtaac taaaagttat gtgagattta
     2281 ataaatatat aaataggttc agttaacatg caatttattt aatatatatt ttaa
//
LOCUS       DAYAKB010000183         2332 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.189, whole genome shotgun sequence.
ACCESSION   DAYAKB010000183 DAYAKB010000000
VERSION     DAYAKB010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.189"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            702..1382
                     /locus_tag="ACGI3L_003754"
     CDS             702..1382
                     /locus_tag="ACGI3L_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199433.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
     gene            1830..2114
                     /locus_tag="ACGI3L_003755"
     CDS             1830..2114
                     /locus_tag="ACGI3L_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199434.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
BASE COUNT         1021 a          156 c          316 g          839 t
ORIGIN      
        1 atattataac tatataaatt atataaatca atacttaaac ataccaatag aggcatttta
       61 aaaaaaacat aaatttataa tataaaattg ttttaagctc cctttcccca aaataggaaa
      121 tttttattag catttaataa tgatttttaa tttttaatat aatattaaag aattatttaa
      181 gaatatttaa tctctaaagc ttaaattaca ataatattat aaaaataaaa gtgatatatt
      241 gtgtaataat cgaaatttta tactttggtt aaaataattt tatatatagt gcctaatgta
      301 taacctaatg ctcgtagaca ataatgtgga tattatcaaa tttattttta taatagaaat
      361 tttaatttat atctatatta aattgttaaa gatataatta tgagaataaa aaatatagct
      421 ttgaattata taattgtata tgcttatctt tatacagtaa ataaaaaatc aaatgaaata
      481 ccaaataaag tgtatatctt aaaataactt actagagata caaggatgct atgtgaattt
      541 tgaagtgtgc agtttagata ataaatatat ataaataata aagaaaatgg atttatagta
      601 tttaaaattt cttataaggg taaaaaatgc tattagaaaa tgtactaaaa atatttttcc
      661 aattctttat agaaaaataa tgatatttag gagagattgt aatgcaaatt gatgtattga
      721 taattgatgg agataagaat agttctcaag agctgaaaaa ttttttagaa ggaaagggga
      781 taaatgtcta tttagcatat aattgtaaag atgctattat aaaaatattt agcaagaaat
      841 ttgacttaat atttttagag ataattttag ttgatggtga tggttgggat ttttgtaaaa
      901 aaattagaaa tataactact tgcccaatta ttcatataac ttatataaat gaaaatcaaa
      961 gtattttaaa tgctttaaat tctggaggag atgattattt aataaagcct ttaaatttag
     1021 aaatattata tgcgaaagtt aaagctattt taagaagaag agatttattt ttaaataata
     1081 ataaaaataa tataaaacta gaagattata atagagctag tggagtaata aagttagaaa
     1141 ataaaatgat aaagttaact ccaacagaaa atagattatt aaattacttt atagagaatg
     1201 ctgaaaagac tctaactatt aaggagatat atgaacatgt atggatgaat gagtatttag
     1261 atgataatta tagtgtagtg gttgctgtga gtggattaag aaagaaaata gagaaagatt
     1321 ataaaaatcc tcaaaaaatt ataacgataa gagaagtagg gtattacttt aacaagatat
     1381 aaagctttat aaacagaatg aatgataagg catagataat atgttagtat attataagag
     1441 tttttgttct aacgatatat ttgtaaaatt agatttaatt tacttaatta aattatagca
     1501 gtagaataaa tataaaaaat gtctgaaata ttatagacat cagtaaaata tataaaacta
     1561 taatataagt cgtaataata aaacaaatga atattaatta ataaaaagat agtagctatt
     1621 tttatatagc tattattttt ttattgttgt ggatgaaaat atacttatat tttactaata
     1681 tacatttaaa aattataatt taaagcatta aaaaataaat ttgtattttg ttttatataa
     1741 agtaatttga agaatatgga aaaacttgat tagtacatta ttaattaggg tataaaatgg
     1801 tgtaaataga atgataaggg gtggatgaaa tgcttgtata taataaaagt ttttatccta
     1861 atgacatatt tccaagatta gatttttcaa aaataaaaaa acagttaaaa ttgatagata
     1921 atgacctgtc agattttgga agcatatgta taatagaaaa agaacattat acaataagtg
     1981 taaacagtat aggtgaaata aatgtgtatt atgatttaga gtacgaaaat aaggtgtata
     2041 gaatagttta tgagattgaa aagttattta aatctcaagt tggaaggttt agcatatcta
     2101 catacagaaa ttgataatta aaaaagtaga aattaaaaaa cttaatacta aagatataga
     2161 taaatatatg aggtaacagc tagagagagt tgttaccctt tttaaatact aagtatatat
     2221 tattcttatt aattttttgt aaattcacta aaagaccttt ttatagaata ttattttctt
     2281 tttttattaa ataggtaaat cagtaaaaat gcaattccag ttccaattat ta
//
LOCUS       DAYAKB010000184         2158 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.190, whole genome shotgun sequence.
ACCESSION   DAYAKB010000184 DAYAKB010000000
VERSION     DAYAKB010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2158
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.190"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            155..850
                     /gene="cas6"
                     /locus_tag="ACGI3L_003756"
     CDS             155..850
                     /gene="cas6"
                     /locus_tag="ACGI3L_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HFG9199435.1"
                     /translation="MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFH
                     NKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQHSDKIKVI
                     TMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSK
                     IDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEI
                     NSRGFGFVNYRWL"
     gene            862..>2158
                     /locus_tag="ACGI3L_003757"
     CDS             862..>2158
                     /locus_tag="ACGI3L_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HFG9199436.1"
                     /translation="MLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKNFSNIDIL
                     EVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKKENLRPDK
                     NNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLNKIRLWIK
                     TNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIIDGKNYGLP
                     NDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLTNKAANGEEVIYISSE
                     KGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIPIEYERHN
                     LKPNLEIGYINNLIKLEKTIDTVFFNKFMCNSYFKEIKNINLSDLVLRDILIRHREGL
                     YTWFYKGRDSIVKQTFSNYSMGIIENSIKNNNYIRAKEQY"
BASE COUNT          970 a          159 c          321 g          708 t
ORIGIN      
        1 tgattttatt tgtcgaataa aaaataaaaa attttaaagg aaaaagttaa aaaataaaga
       61 attttataac tataaattat attttagagt ttattgttat taaatagatg aaaaaatcct
      121 aatatggatt atcagaaaat gaggaggttg ttaattgata aaatgtcttg aaatgtctgt
      181 aaaagtgtat cttcttgaaa atatttcttt agataataca tcaaaagaaa tacgtaaatt
      241 aatagatgat acattaatta tagaagaaaa atataaggaa tttcataata aagctggatt
      301 taagaattat tcttttaatt tattataccc attagaaaaa gataaggttt ataagaagga
      361 ttgtatatat acttttatta ttagaactgt agatagtgaa ttaggaatgt attttatgaa
      421 taatttaaaa aatcagcatt ctgataaaat aaaggttatt acaatgagta aaaaagtgat
      481 ccctaaaaaa catatagaaa gtatttactc tgtcactcca ataatagcta aatttgagga
      541 tgggtattgg agaagtaata aaacagtaga agatttagaa aaaagaatca gagaaaattt
      601 aataaaaaaa tataatgaat ttactaacag taaaatagat gaagattttg aattatttca
      661 agttattaaa tttataaata ggaaacctat ttctactaaa tataagaata tatctttact
      721 tggtgataaa ataagtttta aagtatcaga aaatgatatg gctcaggaaa ttgcaaattt
      781 tgcacttgga gttggagtcg gagaaattaa ttctcgtgga tttggttttg taaactatag
      841 atggttatag gaggtgaaaa cttgttaaag gattgtttag agatttttga aaaagaatac
      901 aaatctttag gaaatagatt gataactgat agctatgtcc tatcctatgg aacatatata
      961 ttggtgaaaa atttttcgaa tatagatata ttagaagttt ctaaaaataa tgtggatagt
     1021 acagaagata tataccataa attttgtgaa ctggattatt tatcaaaact ggtgtctata
     1081 gataaatcag ttgattccaa aaaaataata catagtaata attatctttc attttttgta
     1141 aaaaaggaaa acttaagacc tgataaaaat aataatgtaa aacttacaga agaaattatt
     1201 gataattatt atgatgcttt gttaaaccca agaattaaat ataaatctga taaaagaaaa
     1261 aaagaaatct atgattcaat agaaaataaa tatggtaaag tggatgaaaa taaattaaat
     1321 aaaataagac tatggataaa aacaaatata tttgatttag ttgaatctgt taaaaaagat
     1381 aaaaattatt taaaaatatt ttttgatgaa aaaatagagt tatacaatga tgaaaaccaa
     1441 aaatatttat atccaaatat atataataaa aatgatttca atgtaattat tgatggtaaa
     1501 aactatgggt taccaaacga taatatgcaa ttaaatgaaa aaaagccatt tttgaaatta
     1561 aaaacaagaa ttagaaattc aactccttat ttgattagtg atgatgaagt tttgttacag
     1621 aaagcttttt ttgattatct aacgaataaa gcagcgaatg gagaagaagt aatatatata
     1681 agtagcgaaa agggaattca tagaaaaact gatataccaa atgaatttag tggttatata
     1741 ctgagaataa aaaagggtaa agaattagaa atacatgatt ttgatactgt ggtaaattta
     1801 aacactaaaa taaaaagaat aaatgtagaa tgtataatac caatagaata tgaaagacat
     1861 aatttaaaac caaatttaga gataggatat attaataatc ttataaaatt ggaaaaaacg
     1921 attgatactg tattctttaa taaatttatg tgcaatagtt attttaaaga aattaaaaat
     1981 ataaacttaa gtgatttagt tctaagggat atacttatta gacatagaga aggtttatat
     2041 acctggtttt ataaagggag agatagtata gtaaagcaaa ctttttcaaa ctattctatg
     2101 ggtataattg aaaattctat aaaaaacaat aactacataa gagcaaagga gcaatata
//
LOCUS       DAYAKB010000185         2113 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.191, whole genome shotgun sequence.
ACCESSION   DAYAKB010000185 DAYAKB010000000
VERSION     DAYAKB010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.191"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            114..257
                     /locus_tag="ACGI3L_003758"
                     /pseudo
     CDS             114..257
                     /locus_tag="ACGI3L_003758"
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
     gene            251..1570
                     /locus_tag="ACGI3L_003759"
     CDS             251..1570
                     /locus_tag="ACGI3L_003759"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9199437.1"
                     /translation="MLNINVFWIFLPIFSTAIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIK
                     DNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADK
                     YIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDI
                     CSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKINEVVLKNNKVI
                     TSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
BASE COUNT          896 a          138 c          307 g          772 t
ORIGIN      
        1 attttggatt tttttaccta tattttctac ggcgatagaa tgaattgtat taaaattttt
       61 atcaaatgaa ttcagtgatt taagaaagaa taaattttta aaaatgttac aagagctatt
      121 taattaattt ggagtatatt caatttatat gtaaaaatac tgtagttatt aatggtaaag
      181 atataccagt tagtaaatat agaatggcta atttaaagaa aaaattaaca tatgtattgg
      241 gagatgtatt atgttaaata taaatgtatt ttggattttt ttacctatat tttctacggc
      301 gatagaatgg attgtattaa aatttttatt aaatgaattt agtgagttaa gaaagaatag
      361 attaacccta aatagtagca tagtaattgc tattatgata attactatgt tgaatacaat
      421 tgagtttaat ataaatatta aattatttat atgtatattt attacatatg tattgtataa
      481 aataaattat gtagtggata aatggaaaag tgtatttata agtttgctat attggatgtt
      541 attaattgga tttgatagta ttggattaag tatagtaatg acacttaatt ctataaaaaa
      601 tatgaatgat ttattagagg ataatttgtt gaagttagag ttaataatga tatctaaatc
      661 attactaata gtattaatac cattgcttaa gtttatcaga ttaaaaacaa aaataaacaa
      721 gagggattgt atatatttat ctattccatt aatagcaaac attattggtg taatagtaat
      781 atttgaattt atttttaaag ataagattat cgattctaaa gagagtttaa taatacttac
      841 aatatcaact gtatttttac tatcaaatct ttcattagta agcataatag gaagaataat
      901 aaaagataat agtttaaaga tagaatatga aattacaaaa aaaagaatga atatgcaata
      961 taaatattat ttaaatttac aggaatatca gttgaaaata agaaaactat atcatgatat
     1021 gaataatcat atcatttgta ttcagaatgt ttatgggaaa aatgagtttg cagataagta
     1081 tattaaagat ataaataagc aaataaaaga atgtaatact atatttaata ctcagaatat
     1141 gattctagat gttattttaa gtgataaaaa atctatttgt gatatgaata atatatattt
     1201 tctagtagat attaattttt tagaatgtaa ttttatagag atgccagata tatgtagtat
     1261 attttcaaat ataatagata atgcaataga agcttgtatt aagattaagg acacaagtat
     1321 acaaaaaaag attaaattaa gaggaactgt tataaatagg ttatttgtaa taaaatgtga
     1381 aaatacaaag ataaatgaag ttgtattaaa aaataataag gttattacaa gtaagaaaga
     1441 ttccttttta catggaatag gaataagtag tgtaaaaagt tcagtagaaa aatataatgg
     1501 aaatgtggaa atatactcag ataaaaacaa gtttacaatt actatttata taccattaac
     1561 taggaactaa ttctagttgg ggctctaaat tgcccagttg gagcagtagt attgaaagat
     1621 aaaatagaag atgctatctt taaggcatag gatatttgga ggtgataaaa atggttgaat
     1681 gctatgctaa taagataaca tcctttttag tactcaataa aataatagaa caaaaaatgt
     1741 gatttatatt tgtttgaatt taaaatgttg ataggtttta tagttatatt atttgcatga
     1801 tatatcttaa ataaatttag aaaaatagag ttatttttat ctgcaaatgc gaccttagta
     1861 tggtaacatt attgaccaaa agttctatat agtataaaaa aataaaatgt aaatttgata
     1921 aactttataa ctaggaacat aaaaacaaca attaaataac taattagata gtaaagttga
     1981 tattagtaat aaatattaaa gaaaaatatt ttactaattt gaggaggact tagttgtgat
     2041 agattctgaa gaaatgattt ttaatgtaga agatttaatt atttatagaa aaaatcaact
     2101 agtaattatt tat
//
LOCUS       DAYAKB010000186         2081 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.192, whole genome shotgun sequence.
ACCESSION   DAYAKB010000186 DAYAKB010000000
VERSION     DAYAKB010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2081
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.192"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(109..672)
                     /locus_tag="ACGI3L_003760"
     CDS             complement(109..672)
                     /locus_tag="ACGI3L_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199438.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(770..1699)
                     /gene="glsA"
                     /locus_tag="ACGI3L_003761"
     CDS             complement(770..1699)
                     /gene="glsA"
                     /locus_tag="ACGI3L_003761"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFG9199439.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
BASE COUNT          694 a          402 c          193 g          792 t
ORIGIN      
        1 attaaaaatc attgttttac ccataccaaa aactattttt tgattattaa gtaaattttg
       61 atgttcaatc tctaatatta tatctttaat taatccataa ttaattctct aactaggaca
      121 ttcctcctca agagtaggaa ctataaccat agctatatca tacttagaac cttcaacatt
      181 gtgttgtctt ttatttaaaa tttcatctat ctttgacttc atagtgtcac taagttcaac
      241 taattcatca tgagtaagag aaatatcatg ataatcaact atattttcat tttctaaaac
      301 atcttcctct gctgccttat aaaaaacttc actcatattt tcaaattttg atatgtacaa
      361 ttcttctttt tcttccccat tgtctaaaga aaaattaagt atcctattcc ctataaccac
      421 attttttgca cttggataat agtacttttc cacaatcccc gactttattt tttcctcaac
      481 taattctaaa ataccaactt tgtataacat ttttatatgg tagtttattt ttgcatgagg
      541 ttcttccaat aattgagata attgttttgc tgacaatggc gatttgtcaa atgcttttag
      601 aatatctatt ctacgtggat gcgcaatagc ctttatgcac tccaaatctc gtaataccaa
      661 tacctctttc attgacccct cctaaaaaat ttatttaatt catatttctt tacaatttaa
      721 ttatatatta aattatatgt tgttgtcaaa aaaatccttt cttaatattt taaaaaatat
      781 ttaatttgag tttatttgac aactcctcta aaactttaac tcctgcgacg ctgttacctt
      841 ttttgtcaag cgcaggtcca taaacaccaa tccccatgcg tcccggcaca gaagccatta
      901 taccaccccc aactccagat tttgcaggaa tgccaacttt aatagcaaat tccccagaag
      961 catcatacat tccacaagtc atcataaatg tcttgacaat cctagaaacc atttcactca
     1021 ttaaatgctc accattttct atatctactc cataatttgc aagatttatt ccaattctcg
     1081 ctaaatctac agaatctatc tcaattgagc attgtttaaa ataaaggtct agaacatctt
     1141 ctacattccc tctgataaat ccatcacttt tcaataagta agccatagct ctgtttctat
     1201 ctccagtcat tttttcagac ttatagacat catagtttat tcctatatta tcattttttg
     1261 ctaactttct aaagaaacta agcattcttt cttctttttc ttctaaacaa ctcccattta
     1321 taagggaagt ggttactata gcccctgcat ttatcattgg attacagggt ttttttgtgt
     1381 cattaatttc aagtttcatt attgaattaa atgggtcccc acttggctcc attccaacgt
     1441 ttgaaaaaac gtcttcccaa tcattatcca taagtgccat agcaagcaca attggttttg
     1501 aaatactttg tatagtaaac tttgtgctac agtttccagc actataaaga ttattttcgc
     1561 tatctatgat acaaattcct aaatcatttc ttctagcgtt ttttaattct ggtatgtaac
     1621 tagcgacttg tccataatta gtatacttct tattagaact tataatttct tttaataatg
     1681 tctcatctaa cgtattcata tgcacctctt atattatgtt atatattcta ttttagcaca
     1741 agtttatact ataataaaac aatgttaaaa aaaattatac tttaaaatta ttttctacaa
     1801 gaatcaattc atttttcaaa caatttaaat agtttaaata gcttaataat ttaataattt
     1861 aacaacctag caatttagta atctaataat ccagtaattt aacaacctaa taatttagca
     1921 atctaataat ctaactatct aataatccag taacttaaca acctagtaat ttagtaattc
     1981 aacaatctaa caattcaata atttaacaat ttaacaacct agtaatctaa ctatctaata
     2041 atccagtaac ttaacaacct agtaatttag taattcaaca a
//
LOCUS       DAYAKB010000187         2039 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.193, whole genome shotgun sequence.
ACCESSION   DAYAKB010000187 DAYAKB010000000
VERSION     DAYAKB010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.193"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..646)
                     /locus_tag="ACGI3L_003762"
     CDS             complement(<1..646)
                     /locus_tag="ACGI3L_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9199440.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKKTVVINDEDVPV"
     gene            complement(1737..>2039)
                     /locus_tag="ACGI3L_003763"
     CDS             complement(1737..>2039)
                     /locus_tag="ACGI3L_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9199441.1"
                     /translation="DKITSVTQPTQDATTLTMPTVASGYTIKIKSSTNESVIAKDGTI
                     VPPDTETKVTLVFTVTHTSSGKTADTGEIEVTVPARTTTVSSLLGRIAVNIFNFNK"
BASE COUNT          757 a          279 c          189 g          814 t
ORIGIN      
        1 taactggtac atcttcatca ttaataacca cagtcttttt acatataaat tgaatatact
       61 ccaaattaat taaatagctc ttatgacatc taaaaaaatt atatttttct agctctaatt
      121 ctattttatc catactattt ttagtataat aagtatcatt tttagtatgt atagtcaaaa
      181 cctttttcct aacctctata tacataatac tattaattaa aattttattg attatacctt
      241 tattttctat cagcataaaa ttttctcttt tttttataat atccgatata caactcaaaa
      301 tactttcatt taaatctcca aaatctatag gctttaataa atatctataa gcccttacct
      361 tatagccttc ctgtatgtaa tcaactattg aagttataaa tattatttca gaagtatcat
      421 tagtttctct aattatttta gccacatcca tgcctgttag ttgaagcatt ttaatatcta
      481 aaaaaaatat atcaatacct tctaaatttg tttccaataa ttcttctcct gaattaaact
      541 caaatagttc aatttgacta gaaataccct ctaaggactt taatatacac tctcttaaaa
      601 aagctatttg tgtaatatca tcctcacaga taactattct atacataaac acccctcctt
      661 agacattaga tctgaaaaca aataaaatat caatttataa ataattattt agttatacaa
      721 ctaacatggt catcaaatac tattattcac ttaaaaaatc accccctatt tttagtatgt
      781 taacaacaaa ataagaagat atcttagatt tttaaaaaca attaatactt aatgtagttt
      841 tgtatactat ttataggtaa ttttttatat cattttaaac attaaaatta ttgatgttta
      901 agaactatta tattgatagt aatatataat taatgatatc aaaaattttt aattagactt
      961 ctctcttatt caagattttt ctatataaaa tctaagaata aatagaaaac taacatctaa
     1021 ccttttattt tttattttcg atctatttac ttgaatttta acataaatct atcttttagt
     1081 atatattaat catgctgaat ttgtgatgac atgtatacaa aatatcgttt agtattttct
     1141 aataaaaaat attactgaaa ttaaaaatct acaatagcat ttaacaagta aaaacatgtt
     1201 tacacaaata tataatttaa ggtctttaaa atagagtatg tattattcta aaaattagtt
     1261 atagttatca cataaaaata gaaaagaatt ttcaaaagat ttaaagaaca tatatacttc
     1321 aattgcagaa gatgtaatgt taagtgaact agcattcttc gaggaaaaat agactcaaaa
     1381 aattagaaaa tagaatcagg ttttagatga tttaagtatt tattttcaaa aaagaaattt
     1441 gattctaagt taataaagaa atatttaaaa aaatcaaaaa attttcttaa ataagtaata
     1501 ggttttgtaa aaatggaaaa atatcaaaat aagactatga tttttaaaac tatagcctta
     1561 tcaataaatt tttatttaaa gaacacacat aaatattttt aaacctaatt tatgtgaagt
     1621 tttatgtatt ttttatataa gtagtattct aatcttactc atctaatata ccaaaaagac
     1681 tgtaagtaag ttcactttta tgcaaactta cccacaatct cttttacaca ttaattctat
     1741 ttattaaaat taaaaatatt tactgctatt ctacccaata aagatgatac tgttgttgtt
     1801 ctggctggta ctgttacttc tatttctcct gtatctgctg ttttaccact tgatgtgtgt
     1861 gtcactgtaa atactaatgt tacttttgtt tctgtatctg gtggcactat tgttccatct
     1921 ttcgctataa cactttcatt tgttgatgat tttatcttta ttgtgtatcc acttgctact
     1981 gttggcatag ttagtgttgt tgcatcttgt gttggctgag ttacacttgt tattttatc
//
LOCUS       DAYAKB010000188         1925 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.194, whole genome shotgun sequence.
ACCESSION   DAYAKB010000188 DAYAKB010000000
VERSION     DAYAKB010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.194"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            119..235
                     /gene="rrf"
                     /locus_tag="ACGI3L_003764"
     rRNA            119..235
                     /gene="rrf"
                     /locus_tag="ACGI3L_003764"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            242..316
                     /locus_tag="ACGI3L_003765"
     tRNA            242..316
                     /locus_tag="ACGI3L_003765"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:274..276,aa:Asn,seq:gtt)
     gene            321..395
                     /locus_tag="ACGI3L_003766"
     tRNA            321..395
                     /locus_tag="ACGI3L_003766"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:354..356,aa:Glu,seq:ttc)
     gene            401..476
                     /locus_tag="ACGI3L_003767"
     tRNA            401..476
                     /locus_tag="ACGI3L_003767"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:434..436,aa:Val,seq:tac)
     gene            482..558
                     /locus_tag="ACGI3L_003768"
     tRNA            482..558
                     /locus_tag="ACGI3L_003768"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:516..518,aa:Asp,seq:gtc)
     gene            569..643
                     /locus_tag="ACGI3L_003769"
     tRNA            569..643
                     /locus_tag="ACGI3L_003769"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:601..603,aa:Thr,seq:tgt)
     gene            658..742
                     /locus_tag="ACGI3L_003770"
     tRNA            658..742
                     /locus_tag="ACGI3L_003770"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:692..694,aa:Tyr,seq:gta)
     gene            752..825
                     /locus_tag="ACGI3L_003771"
     tRNA            752..825
                     /locus_tag="ACGI3L_003771"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:784..786,aa:Gly,seq:tcc)
     gene            836..912
                     /locus_tag="ACGI3L_003772"
     tRNA            836..912
                     /locus_tag="ACGI3L_003772"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Arg,seq:tct)
     gene            922..997
                     /locus_tag="ACGI3L_003773"
     tRNA            922..997
                     /locus_tag="ACGI3L_003773"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:955..957,aa:Gln,seq:ttg)
     gene            1009..1084
                     /locus_tag="ACGI3L_003774"
     tRNA            1009..1084
                     /locus_tag="ACGI3L_003774"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1042..1044,aa:Lys,seq:ttt)
     gene            1087..1175
                     /locus_tag="ACGI3L_003775"
     tRNA            1087..1175
                     /locus_tag="ACGI3L_003775"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1121..1123,aa:Ser,seq:tga)
     gene            1193..1283
                     /locus_tag="ACGI3L_003776"
     tRNA            1193..1283
                     /locus_tag="ACGI3L_003776"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1227..1229,aa:Ser,seq:gct)
     gene            1292..1368
                     /locus_tag="ACGI3L_003777"
     tRNA            1292..1368
                     /locus_tag="ACGI3L_003777"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1326..1328,aa:Pro,seq:tgg)
     gene            1454..1529
                     /locus_tag="ACGI3L_003778"
     tRNA            1454..1529
                     /locus_tag="ACGI3L_003778"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1487..1489,aa:Trp,seq:cca)
     gene            1590..1666
                     /locus_tag="ACGI3L_003779"
     tRNA            1590..1666
                     /locus_tag="ACGI3L_003779"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1624..1626,aa:Pro,seq:tgg)
     gene            1673..1749
                     /locus_tag="ACGI3L_003780"
     tRNA            1673..1749
                     /locus_tag="ACGI3L_003780"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1707..1709,aa:Ile,seq:gat)
     gene            1753..1828
                     /locus_tag="ACGI3L_003781"
     tRNA            1753..1828
                     /locus_tag="ACGI3L_003781"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1786..1788,aa:Phe,seq:gaa)
     gene            1836..1912
                     /locus_tag="ACGI3L_003782"
     tRNA            1836..1912
                     /locus_tag="ACGI3L_003782"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1870..1872,aa:Met,seq:cat)
BASE COUNT          484 a          441 c          524 g          476 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc taaaaaaaaa taaaaaaagt
       61 attgacaaaa atagtaaaaa atgttaatat tatacttgtc ctagcaacaa gaaaaaaatg
      121 tggttataat agcggagaag atacacctgt ttccattccg aacacagaag ttaagttctc
      181 tagcgctgat ggtacttggt gggaaactgc ctgggagagt aggacatagc cacgtgaatg
      241 ttccaaggta gctcaacggt ggagcaaccg gctgttaacc ggtaggctgt gggttcgagc
      301 cccacccttg gagccattat ggctcgttgg tcaagaggtt aagacaccgc cctttcacgg
      361 cggtaacagg ggttcaattc ccctacgagt caccatttgt gggatcatag ctcagctggg
      421 agagcacctg ccttacaagc agggggtcac aggttcgagc cctgttggtc ccaccatttg
      481 cggcctggta gttcagttgg ttagaatgcc agcctgtcac gctggaggtc gagggttcga
      541 gccccttcca ggtcgccaaa ataaaaatgc tggtgtggct caacggtaga gcagctgact
      601 tgtaatcagc aggttgtagg ttcgattcct atcaccagct ccatgtaaaa ctaatacgga
      661 ggatttcccg agcggccaaa gggggcagac tgtaaatctg ttgtcatcga cttcggtggt
      721 tcgaatccac catcctccac caattaaata tgcgggtgta gctcaatggt agagttctgg
      781 ccttccaagc cagctgtgag ggttcgatcc ccttcacccg ctccaaagaa agcgtgggtg
      841 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      901 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      961 catgtatgcg taggttcgag tcctgcatcc ccagccaaat aaaaatatgg tctattagct
     1021 cagtcggtag agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg cggatagatc
     1081 accaatggag aggtgtccga gtggtttaag gagctggtct tgaaaaccag tgacttcgaa
     1141 aggggccgtg ggttcgaatc ccaccctctc cgccaaaaaa atgactgaat ttggagaagt
     1201 actcaagtgg ctcaagagga tcccctgcta agggattagg ctgggtaacc ggtgcgaggg
     1261 ttcgaatccc tccttctccg ccattcaaaa acgaggtgta gcgcagtttg gtagcgcaca
     1321 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaac ttaagctttt
     1381 agttcagttg gttagagtgc ccaactcatg gctagtaatt ctagggtttg agtccatgaa
     1441 ggttattctt cataggggtg tagctcagtt ggtagagcgt cggtctccaa aaccgtgcgc
     1501 cgggggttcg agtccctcca cccctgccaa ataaaaagga cttgaaaaaa gttggatttt
     1561 agagtagtat aagatagtaa ataagatttc gaggtgtagc gcagtttggt agcgcacatg
     1621 gtttgggacc atggggtcgg gggttcgagt cccttcacct cgaccaagaa aagggcctat
     1681 agctcaggtg gttagagcgc acgcctgata agcgtgaggt cgctggttcg agtccagcta
     1741 ggcccaccat ttgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc
     1801 ggtggttcga ttccgcctct gggcaccagg aatacggcgg tatagcttag ttggctagag
     1861 cgttcggttc atacccgaaa ggtcataggt tcgactccta ttaccgctac catctaacta
     1921 tatca
//
LOCUS       DAYAKB010000189         1863 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.195, whole genome shotgun sequence.
ACCESSION   DAYAKB010000189 DAYAKB010000000
VERSION     DAYAKB010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.195"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1636
                     /locus_tag="ACGI3L_003783"
     CDS             <1..1636
                     /locus_tag="ACGI3L_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFG9199442.1"
                     /translation="FIKVLTNPMSIVLIILSVIILAFYAFFEFTSVIICFNKSIKYEK
                     IGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIGKIQIPEYILDYI
                     KSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESVNLIKGKIIRTII
                     YSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSI
                     FIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILLISYIESVAFSSH
                     INGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEIDVQETKDGELIV
                     LHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKY
                     SKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKTILQKVKKLDENL
                     LTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKM
                     LDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
BASE COUNT          744 a          164 c          279 g          676 t
ORIGIN      
        1 ttttataaaa gttttgacca atcccatgtc aatagttctg ataatactat cagttataat
       61 actagctttt tatgcatttt ttgaatttac ctctgtaatt atttgtttta ataaatcgat
      121 aaaatatgaa aaaatagggt tatttgaact ctttaaaata tcatttaaga actctataaa
      181 attgttatat cctaaaaata tactattatt tatatttgtg atattaataa ttccattagt
      241 aaatacagtt ttaatttcag ggtttatagg aaaaatacaa ataccagagt acatactaga
      301 ttatataaag tctgatataa ttttaaatat aatctatatg atttttcttt taataatata
      361 tatttcggtt attagatgga tttttagcat tcatgagata actttaaata cagaaaattt
      421 taaaagagca agaaaagaaa gtgttaatct tataaaggga aagattataa gaacaattat
      481 ttattcatta atattatctt tagtagtagc tattattgga tatgcgattt atcatagtgg
      541 aattatattt ataggcatat ggactaaata ttgtactgat atggaatttt tgaagaatgt
      601 atttataaat agatgtattg catttgaaga atattttaga ttgattttat caatattcat
      661 ttttatattg gacattggat ttatctcagc aacttattat caatataaag gagtaaatat
      721 ttctaaaaat aatattaaaa aagagaaaaa atctatatca aaaattgttt ttaatttagt
      781 attaatatta ttgatttctt atatagagtc agttgcattt tcttcacata taaatggtat
      841 gtttaatacg tcattttcat tttatacaac agcaattgct catagagcag gagctgaaat
      901 ggctccagag aatactttgg cagcaataga agaagcttca catgctaaag ctgattatgc
      961 agaaatagat gttcaagaaa ctaaagatgg agaacttatt gtacttcatg attcaaactt
     1021 taagagaact acaggagtag ataaaaatgt ttgggatgta aattataatg aagtaaagac
     1081 atatgatgcg ggaagctttt attattatgg aaaaggttat tatgatgaaa agtttgttgg
     1141 ggaaaagata ccaacactca aagaaatgat aaaatattct aaaggtaagg tgaaattatt
     1201 aatagaaata aaacttaatg gacatgaaaa gggagacgta gtaaaaaaag ttgttcagtt
     1261 aattaaagaa aataattttg aaaatcaatg tatagttgca tctatggata aaactatatt
     1321 acaaaaagta aaaaaactgg atgagaattt attgacatgc tattttatgg caattgcata
     1381 tggtgatttt tcaaagttaa attatgttga tatatatgga attgaatcaa cttttgttaa
     1441 taaaacagta gtagaaaaga ttcataaaat gaacaaaaaa atcttcgttt ggactgttaa
     1501 tagtgacagt ttaattgaga aaatgcttga cctaaatgta gatagtatta ttacagataa
     1561 tccatacctt atagagagtg caatttattg gaagaaaaat ggatttatta gtcaagtgtc
     1621 agattattta ttttaaatat tctataattg tattatccag taaaagagat attattaaaa
     1681 tcaataatat ctctttttaa cataaataag gttgttaaat taaggttatt cttataaaaa
     1741 ttgtgcttat cagctataaa caaggaataa aagtgaaaaa attgctctga gattattaca
     1801 gttaaaagag ttttaagatg acagagagat agattgtcaa ctgtatattt aataaatctt
     1861 gtt
//
LOCUS       DAYAKB010000190         1696 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.197, whole genome shotgun sequence.
ACCESSION   DAYAKB010000190 DAYAKB010000000
VERSION     DAYAKB010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1696
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.197"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..>1696
                     /locus_tag="ACGI3L_003784"
     CDS             <1..>1696
                     /locus_tag="ACGI3L_003784"
                     /inference="COORDINATES: protein motif:HMM:NF012632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199443.1"
                     /translation="ISSYSHNTFILKNDGTIYSCGLNERGALGLGDTTNRNTFTKVNI
                     DNVKDVICGGLHTFIIKNDGTLYSCGMNTSGQLGLGDTNDKDVFTKVNIDNIKEIICG
                     SSHTFIIKNDGSIWSCGLNNYGQLGFSDKVNRNTFTKVDIDNVKKIACGGTTTFVLKN
                     DNTLWCVGENNKGQLGLGDTTNRNTFTKVNIDNVKDVTCSYQGIFIILTDGSVLSTGY
                     NYFGQLGLGDKVDKKIFTKVNVDNVKKIFSGNTHTFIMKEDNKLLFAGSNNFGQLGCQ
                     HFLNNSDNFTTFTEYKNNDYIGFSKSVNLNGDTYLLKDNGEYLLINRNDKIVCGRNFT
                     YILKNDGTIWGAGNNGNGQLGLGDNTHRNVFTRVNIDNVKEIICGNNHVFIIKSDGSV
                     WGTGQNNNGELGLGDNSHRNTFTRLDINNVKKVVCNNCTYVIKNDDTIWVTGYNEHGA
                     LGLGDNTHRKVFTKVNIDNVKEIICGMYHTFIIKNDNTVWACGLNNYGQLGLGDATNR
                     NVFTKVDIDNVKKFICGMYYTFIIKNDNTVWCVGENSKGQLGLGDTTQRNVFTKVG"
BASE COUNT          670 a          135 c          322 g          569 t
ORIGIN      
        1 aaattagttc ttatagccat aatacattta tattaaaaaa tgatggtaca atatattcgt
       61 gtgggctgaa tgagcgtggg gctttaggtt taggtgatac tactaataga aatacattta
      121 ctaaagttaa tatagataat gttaaggatg tcatatgtgg tggacttcac acattcataa
      181 ttaaaaatga tggaacttta tactcatgtg ggatgaatac tagtggtcaa ttaggtttag
      241 gtgatactaa tgataaggat gtatttacaa aggttaatat tgataatata aaagaaatta
      301 tatgcggaag ttctcataca ttcataatta aaaatgatgg aagtatctgg tcgtgtggtt
      361 taaataatta tggacaatta ggttttagtg ataaagttaa tagaaataca tttacaaagg
      421 ttgatattga taatgttaaa aaaattgcat gtggtggaac aactacattt gtattaaaaa
      481 atgacaatac tttatggtgt gtaggtgaaa acaacaaagg acaattagga ttaggtgata
      541 ctactaatag aaatacattt actaaagtta atatagataa tgttaaagat gttacatgtt
      601 catatcaagg tatatttata atattgactg atggctcagt tttatctact ggttacaatt
      661 attttggaca attgggacta ggtgataaag tagataaaaa aatatttact aaagtgaatg
      721 tagataatgt aaaaaaaata ttctctggta atactcatac ttttataatg aaggaagata
      781 ataaactatt atttgctggt tctaataatt ttgggcaatt aggttgtcaa cattttctta
      841 ataattcaga taactttact acttttacag agtataaaaa taatgactac ataggattta
      901 gtaaaagtgt aaatttaaat ggagatacat atttattaaa agacaatggt gaatatttac
      961 taataaatag aaatgataaa atagtttgtg gtcgtaattt tacgtatatt ttaaaaaatg
     1021 atgggactat atggggagca ggaaacaatg gaaatggtca attaggctta ggagataata
     1081 cacatagaaa tgtatttaca agagttaata tagataatgt aaaagaaatt atatgtggaa
     1141 ataatcatgt atttataata aaaagtgatg gaagtgtatg gggtacaggt caaaataata
     1201 atggagaact tggtttagga gataattctc ataggaatac atttactagg cttgatatta
     1261 ataatgtgaa aaaggttgta tgtaacaact gtacatatgt aattaaaaat gatgatacta
     1321 tttgggtaac tggttataat gaacatgggg ctttaggctt aggagataat acacatagaa
     1381 aagtgtttac taaagttaat atagataatg taaaagaaat tatatgtggt atgtatcaca
     1441 catttataat taaaaatgat aatacagtat gggcatgtgg tctaaataat tatggacagt
     1501 tgggtttagg tgatgctact aatagaaatg tatttacaaa ggttgatatt gataatgtta
     1561 aaaaatttat atgtggtatg tattacacat ttataatcaa aaatgataat acagtatggt
     1621 gtgtaggtga aaacagcaaa ggacaattag gattaggtga tactacacaa agaaatgtat
     1681 tcactaaggt tggtat
//
LOCUS       DAYAKB010000191         1624 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.198, whole genome shotgun sequence.
ACCESSION   DAYAKB010000191 DAYAKB010000000
VERSION     DAYAKB010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1624
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.198"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(50..184)
                     /locus_tag="ACGI3L_003785"
     CDS             complement(50..184)
                     /locus_tag="ACGI3L_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199444.1"
                     /translation="MDLINTIDKVQQAHKPIDEIIETIRDIVDIIKILEPVYNFKSNQ
                     "
     gene            complement(594..1424)
                     /locus_tag="ACGI3L_003786"
     CDS             complement(594..1424)
                     /locus_tag="ACGI3L_003786"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9199445.1"
                     /translation="MLNKLCMYLERPELYKQSEINFWDDEYISEQLLKAHLDTNFEGA
                     SRNFNFIEDSVNWIVTVANPVNYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSIN
                     YAQNRNKETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSL
                     KPGGKLILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTL
                     VITEKDENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK
                     "
BASE COUNT          573 a          255 c          132 g          664 t
ORIGIN      
        1 attgtactct tataacattg atgccttaat attattttaa tcttaatcat tattgatttg
       61 atttaaaatt ataaacaggt tccaatattt taattatgtc aactatatct cttatagttt
      121 caataatctc atcaattggt ttatgtgctt gttgcacttt atcaatagta ttaattaaat
      181 ccatttacac atctagcacc tgtatggcaa tttagcatta tccttatctt atactttgtt
      241 gtaaattctt gattacataa ttctattatc taacttatag ctgtgcaatc tacattatct
      301 gtaaatatct ttgctttata tattttccct gaacctctaa cattaatata acagcctttt
      361 tgctatacac ttttaactat atacttaatt ttaataacat tacttgttta taaaaatata
      421 ctatagataa atttcacata aaaataataa ttcaagtatt gatttttata taaacaaatt
      481 tgtaatgtac taaaaataac ataaaagttt ccatttttca atatgtaagc ttttcttatg
      541 ttattttatt gttaaaggtt tcaagttttt atttattcat tttaaaaaaa ttattatttt
      601 tgtaaaacta atcccatagt catactatcg tcagaatatg cttcaccctt aacattacta
      661 aaaaactcaa cagacttaaa tccaatattt tcaacttcta ataagaaact ttcttttgaa
      721 aaatagtgat tccaaacata aaatacattt tcatcttttt cggttattac aagagtttgt
      781 tctaatgtat tataatcatt gtatttacaa ttatcttgta gacacatata tttttcatta
      841 ctccaaaatc ctccatcttc atttatttcc caatatttaa tttcctcaaa attattgtat
      901 ttatttattg taaatacatc taatattaat tttcctccag gttttaaact atcataaatt
      961 ttttccatta ataaccttct attttcagtt gacaaagctc cataatcaca ataaattaag
     1021 gtagccaaat caaattcctc attatagttc atatttaaat aactttgaaa caagtaattt
     1081 atatttaaat tagtctcctt atttctattt tgtgcatagt taatagaacg ttttgagaaa
     1141 tcaattccag ttaccttata acctttttgt gcaaatttct ctgcatataa acctggacca
     1201 caacctaaat caagtaattt aggataatta actggatttg caactgtaac tatccaattt
     1261 acagaatcct cgataaagtt aaaatttcta cttgctcctt caaaattagt gtctaagtgt
     1321 gcttttaata attgctctga aatatactca tcatcccaaa aattaatttc actttgttta
     1381 taaagctctg gtctttctaa atacatacat aatttgttta acaaaacata ccactcctta
     1441 aaatttattt ttaaaataaa aaaaccacag agtttactct gtggtttaac ttcaaaaaga
     1501 tgagtttaaa taagagtaaa atagaaccaa atatttttaa gcacaacaat aaaactatag
     1561 ctttactttg tttgcttatt aaatttgatt ttattcactc ttttccagca atacttatat
     1621 caac
//
LOCUS       DAYAKB010000192         1610 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.199, whole genome shotgun sequence.
ACCESSION   DAYAKB010000192 DAYAKB010000000
VERSION     DAYAKB010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1610
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.199"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(111..1289)
                     /locus_tag="ACGI3L_003787"
     CDS             complement(111..1289)
                     /locus_tag="ACGI3L_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9199446.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
BASE COUNT          576 a          160 c          202 g          672 t
ORIGIN      
        1 ttttagagtt attaatcatt atgtccagat atttaaaaaa attataatga tagagataat
       61 aagataaaaa acatagtgag actacaagta agctcatgta aatattcatt ttagttattg
      121 ttccttttat gattattttg tttattagtg tacattctaa tatcagcaat attaataatt
      181 tcttctacag tcattttgtt ttcgctagaa acttctacaa taccatagct aaaagatatc
      241 gtattatcca taattttact tattttctct ataaattctt ttgtggtgtt ttcattagat
      301 ttaggcataa taactataaa ctcatctcct cctattctag caaatatgtc atctattcct
      361 aagttttcaa taactatact tgagaagtta ataatatagt tatccccagc taaatgtcca
      421 tatgtatcat ttatcgtctt taatttatcc aaatcgatat atatcaatga aaataataaa
      481 ttgttatcaa tgtaatgctg tattttttca aaagcaaatt ttcgattata tgctgatgtt
      541 aattcatcaa tgttagcttt tttctttaat aaatttactt ttagtaattg ttcttgtttt
      601 atcattttta gtctattatg ttctttttct aaataaatat ttttttcaat ggaatatata
      661 tgattgatga atataattag ttgtaagatt aataatatgt tacttcccaa tataaagtag
      721 gaagttagag aacttggtgg agcaaatgta atttgtatac tatcaaataa tatatatcct
      781 aaagtgaacc agataaattt taaaaataga ctgaactcta tttgattttg agttattata
      841 taaatatgct cttttatttt attcatagag taccataaga taaaatctaa aatagaagct
      901 attaaaatac taattaactt ataggtcata tttgcaaata ttatatctgg acttgtattt
      961 ttaacaagtg atattgtact tacagtaata aggtgtaaaa tacaaaaact tattactgcc
     1021 atattgggaa taaaatggtt gttagtagaa ctttttctgc ttaagagcaa tttatgactt
     1081 actatgtaaa acaatatata atatagtggt aatggtaatt ttgtgaatat tattatcaag
     1141 aaggttaatg gttttattaa aaaaatatat ttgtaattct tatgtatagt tatatttttg
     1201 tttccaaaag atgctatttt gcatatgtaa atgttacata gttcgattat taatatagta
     1261 gttatgatta aaaatatatg gtatttcata gtacatcctc ttttaaagtg aaattgtatt
     1321 tacttaaaat agattagatt ttatatattc tattttacag tttttattta ggtacatgca
     1381 aagagcttat tatggatacc ttctttttta ttgcatgtgt ctgtgttata taaaatttaa
     1441 aaagtattat atcttaatat acagtatgta tgataactat gtgtccaaat atagtaatta
     1501 tgtatggaaa gtataatagt tatgtgtata agtatagtaa ttacatatag catgtatgat
     1561 agttatgtgt ataagtatag taattacata tagcatgtat gataattatg
//
LOCUS       DAYAKB010000193         1593 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.200, whole genome shotgun sequence.
ACCESSION   DAYAKB010000193 DAYAKB010000000
VERSION     DAYAKB010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1593
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.200"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            182..1522
                     /locus_tag="ACGI3L_003788"
     CDS             182..1522
                     /locus_tag="ACGI3L_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9199447.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT          623 a          122 c          258 g          590 t
ORIGIN      
        1 aaagcaataa aaagtttaat tcaatttagc aaatttagtg atataattaa aaaagaaaag
       61 aaatatggac ttatttggaa taattttgac aatctattta ctacatgtgt agagtcgtat
      121 ataattaaat tatacataaa atataaaaaa ataatttagt aatacgttag gagaaagtat
      181 tatgataaag tcaagcttat tttggaatat tttcattgcg atatccttta tgatagaatg
      241 gtttctttgt aagaaaatgc tagattatac aagtgagaaa aggatttcta acaaaaaaat
      301 aaacttttgt atggtaggta ttattgtttt tgctgacata atatattttt ttgatgtacc
      361 tccaaatata agagtaatta tatctatgat aattactatt gcattttata aaatctcata
      421 tgatgtgggg tttataaagt ctgtattaat atccttaatt tattggatgt tactaatcgc
      481 cacagatgct ttgagtatat ctttaacagt ttggcttaat tctataaatg acatgagtag
      541 tatggggacg ggagatatat acagaattga gtctataata ttgggaaaga tacttttgat
      601 tgtgtctttg cttttatata gagccttaaa gataaaactt aatatagaaa taaataaaag
      661 gacattattt tatatagtta ttcctatagt cgctaatata gcatcttttt ttgtaatttt
      721 tgaatacata tttaatccag ggtctggtag cttaatacat aatttccaat tcgttatgat
      781 ttctgttgta ttgcttatat caagtatcac tttagtttta attgctaaaa aattacagca
      841 atataatact ttagttgtag aaaacaatat gattaaaaat actttgaagt atgaaaatga
      901 gtattatgaa gatatagaaa agaaatattt aaaaactaga ttactaagtc atgatatgaa
      961 aaatcacata ttgtgtataa atgctatgat taaaaaaggt attgatgtta cttcttattt
     1021 aaataatttg caggtagaaa ttcagagtaa tgacttgtta tttaatactg gtaattttat
     1081 attagatgct atattaagtg aaaagaaaga ggtttgtgat aagaatgata tagaactaaa
     1141 aataggaata aattttagtt gttgtgaagc tgttgaatta gtggatatat gtcatatatt
     1201 ttcaaatatt ttagacaatg caattgaggc atgtaataaa attgatagtg gaaatagagt
     1261 tatttgtgtt aaaggtgatg ttatgcaaaa tttttattta ataagagttg aaaatactaa
     1321 gataaataag attattacta aaaatggaga tattttgaca gacaaaaaag gttctcttca
     1381 tggacttgga ataaaaagtg taaaaaactc tgtaaataag tatggtggta atgttgtaat
     1441 tgaatatgat gataaaaaat ttgtagttaa aattgctatt ccacttagaa atgtgaagaa
     1501 agcagttaat catgtgattt aaatgtatat aaatttgatg tgtagaaatt taatatataa
     1561 gaattaatgt ataaaagtga tgcatagaag ttt
//
LOCUS       DAYAKB010000194         1567 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.201, whole genome shotgun sequence.
ACCESSION   DAYAKB010000194 DAYAKB010000000
VERSION     DAYAKB010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1567
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.201"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            129..>1567
                     /locus_tag="ACGI3L_003789"
     CDS             129..>1567
                     /locus_tag="ACGI3L_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFG9199448.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSE"
BASE COUNT          525 a          159 c          319 g          564 t
ORIGIN      
        1 ttaaaccttg taatttgatt ttataaatat tataattaaa ttaatgaatt tttaacaagg
       61 aattattcat ttttttgatt ttaagattta ttgagaaaac aaaactaaat aggggggtaa
      121 ttaatataat ggattttttc aatggtattt taacgagtat taacaatgca gtagtatatg
      181 taaacaatta cttatggtcg tatatcttaa ttataatgtt agttgtaatt ggtatttact
      241 ttactattaa aacaaatttt gtacaattca gatattttat agaaatgttt agacttctgg
      301 gtgatggtac agcgaataaa aatgcaaaaa aggaaggaaa aatctcttca tttcaagcat
      361 tttgtataag tacatcttca agagttggaa ctggaaatat agctggaata gcaattgcag
      421 tggtagcagg aggacctggt gctgtatttt ggatgtggct tatagcatta attggttctg
      481 catcaagctt tgttgagagt acattagctc agatttacaa agtgaaagat ggtcaagctt
      541 ttagaggtgg accagcgtat tatatggaac aaggtctaaa taaaaaatgg atgggtattt
      601 tattctcaat acttataact atatgttatg gttttgtatt taatgcagtt caagcaaata
      661 ctgtttcact tgcatttaat aatgcatttg gaataagtaa aatggctatg ggaataggtc
      721 ttggaatttt aactgcaata gttatttttg gtggagtgca tagagttgca aaagtttctg
      781 aaataatagt tcctgtattt gcaggattat atatattagt tgctttggct atagttgtaa
      841 tgaatataac agagatacca agtgttatag cattgatagt tgaaagtgca tttgatttta
      901 aaggaatggc gattggtaca tttatgggag ttgtaatgac tggagtgaag agaggtctat
      961 tttctaatga agcaggtatg ggtagtgctc ctaatgctgc tgcaacagca catgtaactc
     1021 atcctgtaaa acaaggttta attcaatctt taggtgtttt tacagatact ataataatat
     1081 gtagttgtac agcattcatg gtattattat attcaggtta tagtagtagt ggagcaactg
     1141 gaattgaatt agctcaagaa gctttaactc atcatatagg accagttgga aatatattta
     1201 tagcagtttg tatattcttg tttgcattta gttctatagt tggtaattac tattatggtg
     1261 aatcaaatat ggagtttatg agtggaagta agactaaact taatgtattt agagtttttg
     1321 ttgtaggtat ggttttattt ggttcactta ctcaagtgga tgtagtttgg aatcttgcag
     1381 acttatttat ggcattgatg gcgataataa acttaatagc aatagcactt ttaggaaaat
     1441 atgcatttat tgctttaaaa gattatacaa gtcaaaaaaa atcaggaata aaagaccctg
     1501 tgtttattgc agatgaaata gaaggcctag aaaaggtatc agagtggcat agggaattat
     1561 ctgagga
//
LOCUS       DAYAKB010000195         1365 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.202, whole genome shotgun sequence.
ACCESSION   DAYAKB010000195 DAYAKB010000000
VERSION     DAYAKB010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1365
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.202"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            116..1156
                     /locus_tag="ACGI3L_003790"
     CDS             116..1156
                     /locus_tag="ACGI3L_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFG9199449.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLSLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          519 a          155 c          204 g          487 t
ORIGIN      
        1 ttttatatac ttttttttta aatatgttta gattctattc ttttaatttt agttttcaga
       61 acatttgtat ttatgttata atttgtataa atatatttat ttaggaggaa acaatatgaa
      121 tttaaattta actaatacta taaatttaat gaaaaaatat ttggacattc caagcccagc
      181 tggatatact gaaaatgcag ttttagaaat caaaaaagat tttgaaaatt taagtcttga
      241 cactattctt acaaaaaaag gtgcacttat agctactctt cctggtgaag atgattcaaa
      301 tcaaataaca atatctgcac atatggatac acttggagct atagtaaaag aaatatcatc
      361 tgatggtact cttaaatacc ataaagttgg tggtggatgt tgggcggcta tagagggaga
      421 aaactgtact gttataacta gaaaaggtaa aaaaatcaga ggaagtgttg tatttaagta
      481 tgcttctact catatatatg gtcaaacaaa agctgccact gaaagaaatg aagaaacaat
      541 gattattaga cttgatgaaa aagtatttac aaagcaagat gtattagatt taggaataag
      601 tgttggggat tttgtatgcc tagaccatag atttgaggct acagaatctg gttttataaa
      661 atctagatat atagataata aatcagctgt agcaatggtt cttgaaatat gtagatattt
      721 taaagaaaac aatttaacac ctaagcatac tactaacttt tatataagta attatgaaga
      781 aattggacat ggtgtttcta aatgtttacc tgaaaaaaca aaagaatttg tagcaataga
      841 tatagcacct actggaccaa gtcaaacatc tagtgaacat ggtgtaacta tagttgcaaa
      901 agataattta tcattatatg attttaattt aagaaacaag cttgtcgatg ttgcagaaga
      961 caataattta gactacgctg tcgatgtatt tactttctat ggttcagatg cttcagaagc
     1021 tattcgttgg ggagaagatg ttcaaatagc atgtgttggt cctggaacaa acaatagtca
     1081 ccattatgaa agaacacata tagaagctat tgaaaataca ctaaaattac ttataaatta
     1141 tatgcttaaa gaataattaa ttatatattt taccaaagtc aattcttaac aaataattaa
     1201 ctttaatttt tatttttata caaaaattgg tttttctata gacttaattt caatttacta
     1261 ctattatata agtaacttca attttcttta gttaattttt attataattt atataaattg
     1321 tataaaaatt ttcttcagtt acttgttgtt aaattaaatt tttac
//
LOCUS       DAYAKB010000196         1286 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.203, whole genome shotgun sequence.
ACCESSION   DAYAKB010000196 DAYAKB010000000
VERSION     DAYAKB010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.203"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(239..949)
                     /locus_tag="ACGI3L_003791"
     CDS             complement(239..949)
                     /locus_tag="ACGI3L_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9199450.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          472 a          168 c          131 g          515 t
ORIGIN      
        1 ctaaaaacta agcttcaaaa aattaaattt tgaaagattg aaattctaga aactgagctt
       61 taaaaaatta agtttgaaaa aaactctaaa aactaagctt caaaaaatta aattttgaaa
      121 gattgaaatt ctagaaatta agcttcaaaa aattaaattt gaaaaaacaa aactctaaaa
      181 actaagcttt aaaaagttaa gtttcaaaaa taaaattcta gagattgaac ttcaaaaatt
      241 aagattctaa catatacctt gtaaattttc ctacaacctc ttgatatttt ttacggctta
      301 taggaatttt ttcattctga actttggcat aagtttgagt tatactatct acatggttta
      361 gattgacaat atacctttga tgcgtacgta taaaattaga gggaagaaca gtttccatat
      421 catttaattt tccgtagtat tctaatgttt tatcaaaggt aactacagtt aattttctta
      481 gctcactttt aaagtagagg atatcttttg tattaatttt acaaagatta gttccaatct
      541 gaactgtaat aaagttttct ttccattgtt ctaatttttt tagtgcttct tttaatactt
      601 tacatatttt ttcagtttta taaggtttta agatgtagtt caaagctcct acatcatatc
      661 catgaaatac atagtcagaa aaacctgtga caaagatgat tatagtatct tttgaatgtt
      721 ttcgtatagt ttttgctatg tcaacgccat tactttttcc aagttcaata tctaaaaaaa
      781 taatatctat gtaataattt tcgtgttcta gattgtatac tagactttct ccatttgaat
      841 attcttttat ttggtagggg tagccccaca aatccatttc tcttgtaatg attttattca
      901 gcatgtttct ttgttgtttt tcatcatcac aaatacaaat cgaagtcaat tttttatctc
      961 ctttcaagtt ttatatttat atagttaagt atataatata ttttgctacc tagatatata
     1021 aaatgaaata acaattatat ccagatagca aaataaaatt ttttatatta gtatacttac
     1081 acttaaaact attctattaa acttattctg aagtgctaat gattttctta ttaaaaaatc
     1141 taacaatctt tcttattata aaatacaaat gcttttatta ttataaaaag taatgatttt
     1201 attactttaa aaatctaata acctttctta ttataaaaca ccaatgattt tattacttta
     1261 aaaatctaat aacctttttt attata
//
LOCUS       DAYAKB010000197         1230 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.204, whole genome shotgun sequence.
ACCESSION   DAYAKB010000197 DAYAKB010000000
VERSION     DAYAKB010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1230
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.204"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            378..623
                     /locus_tag="ACGI3L_003792"
     CDS             378..623
                     /locus_tag="ACGI3L_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199451.1"
                     /translation="MNQKKIKISIKMVIIGIFSVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIIFANCIMFSNILLEIFLIYICRKFRKI"
BASE COUNT          481 a          134 c          134 g          481 t
ORIGIN      
        1 aaaatattaa aaaatacttt agataatcta aagacacatc tcaaagtttt taactaaatt
       61 ataaaactaa ttacaaatgc tatgtaacga taataaataa aaaatttact tcgcttaagc
      121 gacgtgtcgt tgaaatattt catgttgcca actgattcat aagtcgataa gaaaagaaca
      181 ctaattattt agagttcttt tcttagctac aagtggatta taatactttt aaatctgtga
      241 gaaaatcata tataataatg atatgaacaa gtaaagaaaa tacaaaaatg acaaaattat
      301 aaataaaata ttataaaatc ataaggtcat aattgttata ttgtagaaac aaagtaaaga
      361 gagagggtgg agaataaatg aatcaaaaaa aaataaagat tagtattaaa atggtaatta
      421 taggtatatt ttctgtaatt attgcttttg tattatccag attattcgtt gagtatattg
      481 atgaattatt aaggtctaat tggcaatatc agctatttga aagtgagagt tcatatataa
      541 tatttgccaa ttgtattatg ttctcgaata tattattaga aatattttta atatatattt
      601 gtagaaaatt tagaaaaatc taatatggtc aacgtatttc gaatcgaata cttcatgatt
      661 atttagtcta ttgtgctagt taaagtttaa ttcccatata aagtaaattg attttagtaa
      721 aacaaatcac ccctaagggt tagtttatgg ataagtcatc caaatattaa ctctttaatt
      781 tttgctatag attcatcttt gctcataact ttacttataa aaaatgaaat attataagct
      841 agaactttta ttctaattct agtcataaat cctagcatag agttactttt tttatattat
      901 aaataaaact atacaacaaa gataatattt agtaaaaata actttcattt taactaaact
      961 taaaattcaa ttactctcta aattgacgtt taggaattag ttcaaaataa aaaagagtgt
     1021 atatattgaa attactacat ttcaatatat atactctttt taaatttctc agttttccat
     1081 ggaactttac tttatttatt tctgtattag ttgtattttt tatgcatttt tctttaaaat
     1141 catattttct gattcaactc ttatattata aaatttcttt actaaattat tctctttttc
     1201 tatatcttca tatatatttt ttaatcgcct
//
LOCUS       DAYAKB010000198         1157 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.205, whole genome shotgun sequence.
ACCESSION   DAYAKB010000198 DAYAKB010000000
VERSION     DAYAKB010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.205"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(108..887)
                     /locus_tag="ACGI3L_003793"
     CDS             complement(108..887)
                     /locus_tag="ACGI3L_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFG9199452.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT          466 a          186 c           99 g          406 t
ORIGIN      
        1 aataaaaact gtctttttaa aaaattctta taaaagacag ttttatcaat gttatacttt
       61 aatgtttaat taaagccata ttttatttaa atatataact atctatctta gtacatagta
      121 taagattttt ctttatctaa tagtatatcc tctacatctg ggttttcttt tactaattgt
      181 ctataaaaat tacaattagt aacacccaca tatggaatta gccatagtag acctattcca
      241 agagtagcta ttgaaagtat ataccatcct ataaagctaa agtttagtac aaataattta
      301 agtacatttc ctttcatcat atctaaacta gcacccattg atttaaatac acccatatta
      361 tccttgtctt cacaaattaa gaaagtagct tgagaaacat ataatagcaa tatataaact
      421 ggtaacataa gaacaagtat tataagaact agagttattc cagtagaaat aatagtccct
      481 attccaacat tatcacttga taaatattca attgctccac tagtaagtaa aactccaaat
      541 gataaaaacg ctcctataat tgtgattata aaagaataaa tatacacaat aattgattca
      601 aataaataaa aaccaaaact tcttaaataa attctcccac ttacaaagat atctcctatc
      661 ttgacttttt catctttagt aattttcaag aacatacatg taaatcctgc tgaaacgcaa
      721 aaagctatta cagccactac aatagtagtc aatggttcaa aaggtaatcc tacaattgat
      781 attaatacta tcaatgcaat atatactgcc atagaaattg cacatatccc ccagtttcca
      841 gataactgag ctttagatac tcgttttaat tcttgccttg ataccataaa aaacacccct
      901 ttcattttat aaaaaaactt ttaaaaatat aaataatctt ttaacgtata atattaatat
      961 atcatatttt cgactatata agatacaatt attcaccatg ttttatcaag atatgccata
     1021 attgtattac tagttttata tagtcaacat taccaaatac atcaaataaa tttgattaat
     1081 tattcaacaa gtaataaaat aatttctatt aattatactt tatttagtaa acaaattatt
     1141 taataaaaaa attacct
//
LOCUS       DAYAKB010000199         1123 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.206, whole genome shotgun sequence.
ACCESSION   DAYAKB010000199 DAYAKB010000000
VERSION     DAYAKB010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1123
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.206"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            195..299
                     /locus_tag="ACGI3L_003794"
     CDS             195..299
                     /locus_tag="ACGI3L_003794"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFG9199453.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
BASE COUNT          427 a          105 c          178 g          413 t
ORIGIN      
        1 gcttttctaa gtgcattaaa tgaagaaata tatattataa aatatatatt tcttaatggt
       61 gttagatata catatattat acaagagttg gtcgttgcct tgacaatgct cctatggaag
      121 gattttgggg aattttaaag gtagaaatgt actatttaag gaaatttgat acatatgaat
      181 aattagttaa agcaatagat gattatatat actactataa taattttaga tatcaaaata
      241 gattaaattc tatgtctcca tttgaattta ggaaatattt aagtacagag agagcataat
      301 ttattttaag tatctctaaa aaaattaaat atctagggtt ttatttgacg tgctcttttt
      361 tagatagtaa gctttaaaat atagatatta attatatgaa tataataaaa agagtactaa
      421 tgagttacac tagtacttta taactatttt tacatgtttt aactgtataa aacagcgggt
      481 atagttcaca caggcaggag tgactttagt tttgaactaa aaatcaagtt caaaaagaat
      541 aaacattagt atttgaactt cactctacgt ctaaatagat tgtagttctt cttgctttta
      601 ttataccaca aattggtata gatattcaaa aataatatat ttatgatata ataaaaatgt
      661 aaatagtttt gcagtgagcg atatttgtta caaagtagag cttaacgctt gaaatataag
      721 gtgttgaggg tatatgataa gctttatcat ttgcactact catggttcac tgcaaattta
      781 agagagttgc atatgtgtaa gtattgaaaa tgcccagttt atttgggggt tttatattaa
      841 ctaagtggta tgtaaataga gagataaggc aaataatctg taacaactcc aaagttttat
      901 attaactaag tggtatgtaa attctgaata cggaacataa atagcaacag taccagaatg
      961 ttttatatta gctaagtggt atgtaaataa tgatttatta aaaattttta tttgttttga
     1021 tattgtttta tattaactaa gtggtatgta aatagagtaa aacaatagta caagaacaaa
     1081 taaatacatg ttttatatta actaagtggt atgtaaatac ttt
//
LOCUS       DAYAKB010000200         1113 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.207, whole genome shotgun sequence.
ACCESSION   DAYAKB010000200 DAYAKB010000000
VERSION     DAYAKB010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.207"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            61..645
                     /locus_tag="ACGI3L_003795"
     CDS             61..645
                     /locus_tag="ACGI3L_003795"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HFG9199454.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKGLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT          420 a          116 c          175 g          402 t
ORIGIN      
        1 ttaataaatc ttatgctaga atatatatga aaaacaatat aaatttggag gattaaaaac
       61 atgacagagc gagaaaaaat gttggcagga gaactttacg attgtggtga tattgagttg
      121 ttaactcaat ggcataaagc aaaaggccta gtaagagatt ataaccaaac agattcctcg
      181 gatttggaaa aaaaagaaaa aatattaaat gagttacttg gtggtaaggg taaaaactta
      241 tggattactg caccgtatta tgtagattat ggaaataata tttattttgg aaataattgt
      301 gaagtcaata tgaattgtac gtttttagat gataataaaa ttatcattgg ggataatgca
      361 ctaatcgcac caaacgtaca aatatatact gcatttcatc caactaatgc tggtgataga
      421 tttggtaatg ccaaagaaga tggttcattt gaattttgta aaactcaaac agctccagtt
      481 actattggag ataatgtttg gattggcggg ggtgctatta tcatgccagg tgttactatt
      541 ggagataatg tagttatagg tgcaggaagt attgttacaa aagatattcc aagtaatatg
      601 attgcatacg gaaatccatg ccgtattatt cgagaaaata aataaagtta aattttcttg
      661 caaaatctca aaaaacacct ttcttacttt atacataggg tattttctaa tactttcaca
      721 tccatattca tttgttaaat ttttgtggaa tgtagttttt atcacttcta tcttacattt
      781 ccaccatttt tttataaaag tcattccttt atagatttat ttataatagt atatattcta
      841 tttgatgttt gaataagcac ttatttttaa gtaaaatact aacttttagg ttagtatttt
      901 gctatagtat gatgattaag taagaataaa atactataat acataaagct taataaatat
      961 aatttttatt ttacttagat attttctttt gattagcaat caaaagtagt tataattttt
     1021 ttaattaata agagtaacat ttattttatg aaagaggatt atattaatat atatttaaat
     1081 aggaaaaatt gtaaaaagca taaaaataat ata
//
LOCUS       DAYAKB010000201         1099 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.208, whole genome shotgun sequence.
ACCESSION   DAYAKB010000201 DAYAKB010000000
VERSION     DAYAKB010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.208"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(2..73)
                     /locus_tag="ACGI3L_003796"
     tRNA            complement(2..73)
                     /locus_tag="ACGI3L_003796"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39..41),aa:Asn,seq:gtt)
     gene            complement(80..153)
                     /locus_tag="ACGI3L_003797"
     tRNA            complement(80..153)
                     /locus_tag="ACGI3L_003797"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(119..121),aa:Cys,seq:gca)
     gene            complement(161..236)
                     /locus_tag="ACGI3L_003798"
     tRNA            complement(161..236)
                     /locus_tag="ACGI3L_003798"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(201..203),aa:Lys,seq:ttt)
     gene            complement(245..321)
                     /locus_tag="ACGI3L_003799"
     tRNA            complement(245..321)
                     /locus_tag="ACGI3L_003799"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(285..287),aa:His,seq:gtg)
     gene            complement(329..405)
                     /locus_tag="ACGI3L_003800"
     tRNA            complement(329..405)
                     /locus_tag="ACGI3L_003800"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(369..371),aa:Pro,seq:tgg)
     gene            complement(429..505)
                     /locus_tag="ACGI3L_003801"
     tRNA            complement(429..505)
                     /locus_tag="ACGI3L_003801"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(469..471),aa:Ile,seq:cat)
     gene            complement(520..593)
                     /locus_tag="ACGI3L_003802"
     tRNA            complement(520..593)
                     /locus_tag="ACGI3L_003802"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(557..559),aa:Met,seq:cat)
     gene            complement(600..675)
                     /locus_tag="ACGI3L_003803"
     tRNA            complement(600..675)
                     /locus_tag="ACGI3L_003803"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(640..642),aa:Phe,seq:gaa)
     gene            complement(679..767)
                     /locus_tag="ACGI3L_003804"
     tRNA            complement(679..767)
                     /locus_tag="ACGI3L_003804"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Ser,seq:tga)
     gene            complement(856..931)
                     /locus_tag="ACGI3L_003805"
     tRNA            complement(856..931)
                     /locus_tag="ACGI3L_003805"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(896..898),aa:Gln,seq:ttg)
     gene            complement(939..1015)
                     /locus_tag="ACGI3L_003806"
     tRNA            complement(939..1015)
                     /locus_tag="ACGI3L_003806"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(979..981),aa:Arg,seq:tct)
BASE COUNT          297 a          294 c          250 g          258 t
ORIGIN      
        1 gctccaaggg tggggctcga acccacagcc taccggttaa cagccggttg ctccaccgtt
       61 gagctacctt ggaatatttt ggaggcgaca cccagattcg aactggggat caaggagttg
      121 cagtccactg ccttaccact tggctatgtc gccacctttt tggtgatcta tccgcgactc
      181 gaacgcggga caccctgatt aaaagtcagg tgctctaccg actgagctaa tagaccatat
      241 gaattggggt ggataatgag agtcgaactc acgacctcca gagccacaat ctggcgctct
      301 aaccaactga gctataccca ccttatattg gtcgaggtga agggactcga acccccggcc
      361 ccatggtccc aaaccatgtg cgctaccaaa ctgcgctaca cctcgaattt atattaatta
      421 atttaatgtg gtgggccatc agggactcga accccagacc taccggttat gagccgggcg
      481 ctctaaccaa ctgagctaat ggcccacatt aaattttagt agcggtaata ggagtcgaac
      541 ctatgacctt tcgggtatga accgaacgct ctagccaact aagctatacc gccatatttt
      601 ggtgcccaga ggcggaatcg aaccaccgac acggggattt tcagtcccct gctctaccga
      661 ctgagctatc tgggcatttg gcggagaggg tgggattcga acccacggcc cctttcgaag
      721 tcactggttt tcaagaccag ctccttaaac cactcggaca cctctccaca ttcggatact
      781 taaacttatt ctaaaattga acctaactat atttaaaata aaaataattc aaatatagct
      841 tagtaataca tcatttggct ggggatgcag gactcgaacc tacgcataca tgagtcaaag
      901 tcatgtgcct taccgacttg gctaatcccc aatatatgtg gtgagcgcac agggattcga
      961 accccggaca cacgccttag aagggcgttg ctctatccag ctgagctatg cacccacaat
     1021 ttatatatgt atatcaaaca aaaatggtgc ggatgaaggg agtcgaaccc ccacgccaat
     1081 ggcgctagat cctaagtct
//
LOCUS       DAYAKB010000202         1023 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.209, whole genome shotgun sequence.
ACCESSION   DAYAKB010000202 DAYAKB010000000
VERSION     DAYAKB010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1023
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.209"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            383..850
                     /locus_tag="ACGI3L_003807"
     CDS             383..850
                     /locus_tag="ACGI3L_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9199455.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          389 a           68 c          165 g          401 t
ORIGIN      
        1 tttttattaa ttataatatt tgaataatct ttttaatcat ataaaatgca tatacttgta
       61 atatttaaag gtgatattaa tattattagt gtatattaat attcccttga aattaaaaaa
      121 acatagatat ttcagtaatc taaaatagtc tacaaaaata acagttttag caaaattaat
      181 aagaatacat atagatttaa acctaaaagt atgaacatgt ctgtttttta caagattaaa
      241 atttatatta tatgataaaa ttaacttaac tatttcaata agacttataa tttttttctt
      301 tatactagac cttattgaaa cctttatagt ttaattctaa ttatatatta taaataaagt
      361 atgtgtatat taaggaggta atatgaagtt tttaaatgtt ttagtagtag ttgaagatat
      421 tgagaaatca aaaaagtttt attatgatgt tttggggtta aaggtaatct gtgattttgg
      481 agaaaatgtt gtattagaag gtaatatatc attacaagaa aaaaagcttt ggttagaatt
      541 tattaataag agtgacagtg aagttaagtt caatggaaat gatgctgagt tatattttga
      601 ggaagataat tttgatactt ttgttgaaag attgagtaca atgaaagata tagattatgt
      661 tcatctagct atagagcata ggtggggtca aagagcaatt agattttatg atttagatgg
      721 gcatattatt gaggttggag aaactatgtc atctgtgtgt agacgttttt tagatagtgg
      781 tctttcaata gatgaggtag ctaaaagaat ggatgtaact gtcgaatata ttgaatcagt
      841 tttagaatag atggattata ttaaagtaaa attgaggtga aggctgtaag taaacttgtg
      901 tgaaaacaaa tttgcttaca gtttttattt ttctaaaata aagaatataa tacttgttta
      961 gctttatttg agtttttaaa aatattatga tatttcttat atatttatac taaagtttaa
     1021 att
//
LOCUS       DAYAKB010000203          976 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.210, whole genome shotgun sequence.
ACCESSION   DAYAKB010000203 DAYAKB010000000
VERSION     DAYAKB010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.210"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(137..820)
                     /locus_tag="ACGI3L_003808"
     CDS             complement(137..820)
                     /locus_tag="ACGI3L_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFG9199456.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT          383 a          151 c           77 g          365 t
ORIGIN      
        1 ttactatact taaaatactt ctattaactt atacattgct tactatattt taaattcttt
       61 aattaatcta tacaatattt gctatatata aagtatatca aataacagct tcattttttt
      121 gtaaatttac agaaagttaa ttttcattaa atgaatcatc tttattgata aacataattc
      181 caaagaccac tgccaaaata aaaaaacata ttagtattga tttttccacg aaaatttttg
      241 taaaaaaagt tcctaaaata gctccagata taaagaatat aataatagca taatactgta
      301 aactcttttt tatcataaaa atattcttag tatgtatata atgaaataaa gtttctgtag
      361 cacttcttaa atttccagta cacattgtcg ttgcaaaact attcccattt acttttctaa
      421 aactctctac ttgcattgaa caaataaaag aaatagcaac atttacaaac atattaaatc
      481 ttcctctagg aataaatgaa acaataagta ttgtaatcat ttcaattata atgataacct
      541 gacgccaatg aatctttgtc ttattatttg taaaatactt tcttatcttc tcggctataa
      601 atacacctaa cataaatgcc aaaataggaa tcaaataata aaatgattcc tttacattac
      661 cttctgctat attaagccca aataaaacta tatttccagt ttgtgcatta gcaaagactt
      721 tacctcttac cacataagta taaatatcca aaaatcctcc tgttattgcc aacaaagaac
      781 ataaaaagaa tgattcagac atctgactct tgcttgtcat atataaacct ctcgctttct
      841 aatgatagat acaaaatcaa aatcatttta gattctattt ttcattgata taaaaaaatt
      901 atttatattt aaatattgtc tatatttata cattatttgt atttatatag cattcatatt
      961 tatttatatt taaaca
//
LOCUS       DAYAKB010000204          956 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.211, whole genome shotgun sequence.
ACCESSION   DAYAKB010000204 DAYAKB010000000
VERSION     DAYAKB010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.211"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            285..689
                     /locus_tag="ACGI3L_003809"
     CDS             285..689
                     /locus_tag="ACGI3L_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HFG9199457.1"
                     /translation="MDKTLKKDLNQEYTESKSLIMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            706..>956
                     /locus_tag="ACGI3L_003810"
     CDS             706..>956
                     /locus_tag="ACGI3L_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199458.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIY"
BASE COUNT          403 a           80 c          142 g          331 t
ORIGIN      
        1 actaattacc aatattatac atttaataaa tgtaatgtat tttatgaaag tctgccatat
       61 taaatagatt taaatttttt taaaaaattt ataaatattg ttcaaaaatc ctgccaataa
      121 attggaaata ctaaattaaa aaaataataa agtttagctt atagctaaat aaaagtttac
      181 ttataaggtg aactttttgc attttcagtt ttgacataca tatttttttg taatatattt
      241 atattatcaa ttagagataa ggagagtgag aagagatatt taatttggat aagacattaa
      301 aaaaggattt aaatcaggaa tatacagaga gcaaaagttt aattatgaat aaaagtaagt
      361 atatgaatgt ttgttttaag aattatatta aagtagtaga aggaatgtat actaagaggg
      421 atttaattcc attaaaatta ataaactcta tggataaaaa taataagatt agaaaaacat
      481 tatatgaatt atcttgtgaa tttgaatatc caaaaacttc tttatcttca ttgtttacgg
      541 agctgaaaaa aatggatttt ttacaaagag tgaaaaatgg tgagtatatg ataaatccac
      601 atatagcata taaaggtagt agagctgata aagaaagttt attagcagaa tataatcaga
      661 taaaaagacc taataaggtt agtaaataag gaagaaggtt tttatatgag tttaaaactt
      721 gatagaaatg ttctacagtg gtttgactat gtatttgaga atgaaaaaac tagtttgaga
      781 cactataatt ttaattgtac actaaaggag attagttcta ccagtttgaa caaagtagct
      841 tttattttag aaaaaaataa ctctaagtac tggaagcttt attttgaaat accagctgaa
      901 gttactttaa aacttaagca aaacattcat cctttattta gggaatatat atacga
//
LOCUS       DAYAKB010000205          859 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.212, whole genome shotgun sequence.
ACCESSION   DAYAKB010000205 DAYAKB010000000
VERSION     DAYAKB010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.212"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            106..810
                     /gene="cwlD"
                     /locus_tag="ACGI3L_003811"
     CDS             106..810
                     /gene="cwlD"
                     /locus_tag="ACGI3L_003811"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HFG9199459.1"
                     /translation="MRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTII
                     LDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEEN
                     NKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKELS
                     KCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQ
                     EKIAWAIYIGIQKYLS"
BASE COUNT          377 a           94 c          134 g          254 t
ORIGIN      
        1 ataccaataa ataaagatat atcaatatta aaaaaattta aatgtttgta ctaatatatg
       61 gaatattata gtgtttttat aagtatacat atacagggtg atgttgtgag aaagtacata
      121 aaacatataa tttttagttt tgcaatgata tgtctagtag tagtatccat atttgaaatt
      181 aaaaatattt ctgaagatgt tatcaagtat atgccagtaa caaacaaaac tataatttta
      241 gatgctggtc atggaggcat tgatccaggt gcattaaata aggataagag tacatctgaa
      301 aaggatatta acctagcaat aacacttaag cttagagagc ttatagaatc aagtggtggc
      361 cttgtaatat taactcgaga agatgacagt agcctttata aagaagaaaa taataaaact
      421 acaagacaaa aatataatga gaatttgaaa aatagaaaag aaataatatc taattctaat
      481 gccaatatgt ttgtctctat acatcttaat gcatttgaac aatcaaaata ctatggagct
      541 caaacttttt atcctaaaga caaacaagac agtaaagaat tatcgaagtg tattcaagaa
      601 gaacttaaaa gagtagtaga taagacaaac aacagagaag tcaaaccaag ggatgatata
      661 tatcttttga aagaaaataa tattccatca gtactgatag aatgtggttt tttatcaaat
      721 gaaaaagagt gtaaactctt aactgatgaa acatatcaag aaaaaatagc atgggcaatc
      781 tacataggaa tacaaaaata tttaagttga aataactata aaaataggtc taaatatgta
      841 aatagcttgt attaaagca
//
LOCUS       DAYAKB010000206          824 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.213, whole genome shotgun sequence.
ACCESSION   DAYAKB010000206 DAYAKB010000000
VERSION     DAYAKB010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.213"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            146..388
                     /locus_tag="ACGI3L_003812"
     CDS             146..388
                     /locus_tag="ACGI3L_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199460.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            536..727
                     /locus_tag="ACGI3L_003813"
     CDS             536..727
                     /locus_tag="ACGI3L_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HFG9199461.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
BASE COUNT          363 a           52 c          135 g          274 t
ORIGIN      
        1 ggaatatatt aaattgtatt aatatagttt aaattgaata aaactgttag ttttgcatct
       61 gaaaattatt ttgtttaaaa aaatttttta gacaaataat aaccttaata gataaaaaga
      121 ttaataaaag agtaaaggat gatatatgtt ggaagtaacc aaaataataa ttaaatattt
      181 tgcaagtgaa agtgatactt ttgtaaaaga agaagtttgt aattttgaag aacttcttaa
      241 gtggtctcat aaatttattg aaggtaaaaa gatagaagat gttttgtata taaagtctaa
      301 agaaaactat aaagtaaatg tgattaagtc tttagaaatt aaggaattgg aaatagtgag
      361 aaaacaacag ataccaccgt acatgtagta ttaataatat ataaaattaa tatgtaatac
      421 tcgcaatagg atataaatgg tatatatggt aataatttat attaaaaaaa cttttataaa
      481 gtttatattt gggtataaaa gtattaatta gacattaatt aggaggaact taaatatgat
      541 aagagtatgt ccaaactgtt caaatgtgga tgtaaataag ctaaaaactt tggttggaga
      601 agaaaatgta aagactggtt gtataggtca gtgtagagca tttaaaaaag aagctgttgg
      661 aataatagac aatgagcttg aaataaagga aacagaagca gagttttttg aagcatgtaa
      721 agaataaatt ttaaataaaa tataataaat agagcatcta aattgtataa gcattaaaca
      781 atttagatgc tctattttta tatatacatt taattatgag tata
//
LOCUS       DAYAKB010000207          818 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.214, whole genome shotgun sequence.
ACCESSION   DAYAKB010000207 DAYAKB010000000
VERSION     DAYAKB010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.214"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            26..415
                     /locus_tag="ACGI3L_003814"
     CDS             26..415
                     /locus_tag="ACGI3L_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9199462.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            408..>818
                     /locus_tag="ACGI3L_003815"
     CDS             408..>818
                     /locus_tag="ACGI3L_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199463.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFIPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYAKLGHIDIDSKLIVDMDFINKKN"
BASE COUNT          324 a           76 c          119 g          299 t
ORIGIN      
        1 ttataaagca taatggaggt tttttatggt tttaaattta gattttaata gtgataaatc
       61 tatttatgta caaattaaag aagaaataac taaggctata gcttcaggag aattgaaaat
      121 aaatgaatca cttccatctg taagaagtat ggctgaaaat attggtgtaa atttacatac
      181 agtgaacaaa tcctacaatg aattaaaaga agagggattc ttaaatattg atagaagaaa
      241 aggtgctatt gtagctcaac taccaatgaa aatagataat acaactcgtc aaaaaaataa
      301 acttgacttg gaattattgg tggcaaaatc ttatttatca ggtattagta aagaagaatt
      361 tttgtcacta agttcaagtt tatttgacaa gtatgaggtg aaatattatg agtaagattg
      421 aatgtctatt tacaatattt ccagttctaa ttttgatgta tgctacattt tattttatac
      481 cctattttgt aggtaaaaaa cacatctatg gagtttctat agaccaagag cataaaaatt
      541 ataattactt tataaagtta gataaagaat ttaaaaaact attatcttta ggttttatta
      601 tagactttat attagttttt attctggtct ttacatttaa taaattggaa ctttcctatt
      661 ttattggtat tataggtttt ttattatatg aaagtatact atatattcat acacataaaa
      721 aagctaagaa gcttaaatca gaaatttatg ctaaattagg tcatatagat atagattcaa
      781 aattaatagt agatatggat tttataaata agaaaaat
//
LOCUS       DAYAKB010000208          787 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.215, whole genome shotgun sequence.
ACCESSION   DAYAKB010000208 DAYAKB010000000
VERSION     DAYAKB010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.215"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..>787)
                     /locus_tag="ACGI3L_003816"
     rRNA            complement(<1..>787)
                     /locus_tag="ACGI3L_003816"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          238 c          182 g          195 t
ORIGIN      
        1 cgtccatccc ggtcctctcg tactaaggac aggtcttctc aaatttccta cgcctgcgac
       61 ggatagggac cgaactgtct cacgacgttc tgaacccagc tcgcgtacca ctttaatggg
      121 cgaacagccc aacccttggg acctactaca gccccaggat gtgatgagcc gacatcgagg
      181 tgccaaacct ccccgtcgat gtggactctt gggggagata agcctgttat ccccagggta
      241 gcttttatcc gttgagcgat ggcccttcca cgcagaacca ccggatcact aagtccgatt
      301 ttcatccttg ctcgacctgt atgtcttgca atcaagctct cttttgcctt tacactctac
      361 gtacgatttc cgaccgtact gagagaacct ttgagcgcct ccgttacctt ttgggaggcg
      421 accgccccag tcaaactgcc cacctgacag tgtcccaaga ccagattcat ggcctatggt
      481 tagagtccca gtactacaag ggtggtatcc caaggatggc tccgccaaaa ctggcgtcct
      541 ggtttcaaag cctcccacct atcctgtaca tgtagtacca agacccaatg tcaagctaca
      601 gtaaagctcc atggggtctt tccgtcctgt cgcaggtatc cggcatcttc accggaatta
      661 caatttcacc gagtctgttg ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc
      721 ggaacttacc cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt
      781 actgggg
//
LOCUS       DAYAKB010000209          753 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.216, whole genome shotgun sequence.
ACCESSION   DAYAKB010000209 DAYAKB010000000
VERSION     DAYAKB010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.216"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..>753
                     /locus_tag="ACGI3L_003817"
     rRNA            <1..>753
                     /locus_tag="ACGI3L_003817"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          227 g          163 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tac
//
LOCUS       DAYAKB010000210          664 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.217, whole genome shotgun sequence.
ACCESSION   DAYAKB010000210 DAYAKB010000000
VERSION     DAYAKB010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.217"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..>664)
                     /locus_tag="ACGI3L_003818"
     rRNA            complement(<1..>664)
                     /locus_tag="ACGI3L_003818"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAYAKB010000211          577 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.218, whole genome shotgun sequence.
ACCESSION   DAYAKB010000211 DAYAKB010000000
VERSION     DAYAKB010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.218"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..>577
                     /locus_tag="ACGI3L_003819"
     rRNA            <1..>577
                     /locus_tag="ACGI3L_003819"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAYAKB010000212          567 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.219, whole genome shotgun sequence.
ACCESSION   DAYAKB010000212 DAYAKB010000000
VERSION     DAYAKB010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.219"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..418
                     /locus_tag="ACGI3L_003820"
     CDS             <1..418
                     /locus_tag="ACGI3L_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFG9199464.1"
                     /translation="TFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQKN
                     NKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIFGK
                     INSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
BASE COUNT          259 a           53 c           76 g          179 t
ORIGIN      
        1 tacatttaaa actgaagttt tattaaaata ttctgcaaaa gacatattta atatatttac
       61 aaaatctgca agactaaatt ttcctaattt taatgagaaa aaagcagtag gaacatttgt
      121 acagcaaaaa aataataaaa gatttaaggt tgaaataact aatttcgaaa aaaatagagt
      181 atatgagata aaaacaagca ataaaagaga aagtactatt actagatatg aattagtaca
      241 tattgactta gaaaatacaa aacttatttt tattgaaagt gagagcaaga ggaatatatt
      301 tggaaaaatc aattcagctc ttgtaagagt attgtttgga aaaaggcaac cagaagaatt
      361 taataaattt ataaaaaaac tagaaatgga attggagaat aatagtgtta atttatagat
      421 ataagttaga ttatatattt aaaatctatc taaaaacata tttctaagta ttttatgagt
      481 cctactattc gttacaataa ttaatgaaaa aactattgat aaacatgtga cactatgact
      541 atataccaca ttaagagtat cattagc
//
LOCUS       DAYAKB010000213          493 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.220, whole genome shotgun sequence.
ACCESSION   DAYAKB010000213 DAYAKB010000000
VERSION     DAYAKB010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.220"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="ACGI3L_003821"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="ACGI3L_003821"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="ACGI3L_003822"
     tRNA            310..398
                     /locus_tag="ACGI3L_003822"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
     gene            410..486
                     /locus_tag="ACGI3L_003823"
     tRNA            410..486
                     /locus_tag="ACGI3L_003823"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Ile,seq:cat)
BASE COUNT          156 a           91 c          109 g          137 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgaa tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 tcagttggtt agagcgcccg gctcataacc ggtaggtctg gggttcgagt ccctgatggc
      481 ccaccacaat aat
//
LOCUS       DAYAKB010000214          401 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.221, whole genome shotgun sequence.
ACCESSION   DAYAKB010000214 DAYAKB010000000
VERSION     DAYAKB010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.221"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(182..358)
                     /locus_tag="ACGI3L_003824"
     CDS             complement(182..358)
                     /locus_tag="ACGI3L_003824"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199465.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
BASE COUNT          161 a           60 c           30 g          150 t
ORIGIN      
        1 ttgtgtatta ccacaaatac tattgtatca tagattaata gaaatgtcta cttaattata
       61 ttttttagtt aacattttaa ttattcttaa tattaaaaat atatttaaac gttttacatt
      121 gctatatatt aatataaatg tagataaaac taaaaagggt tttctagaaa tcaatgtcta
      181 tctaattata cttacttacc aataccatta cttggtgtaa acaagactct actacatttt
      241 ctccgtactc taatataaaa tcatctaact gtgtatctaa aaaattacaa taatcatacg
      301 aactgctaat ataagcagtc aatacatgtg tacatttatc cattttattt ccaaacatat
      361 aaattattat ccccctaaaa aactttcata aaaacaaaaa g
//
LOCUS       DAYAKB010000215          364 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.222, whole genome shotgun sequence.
ACCESSION   DAYAKB010000215 DAYAKB010000000
VERSION     DAYAKB010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.222"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            168..284
                     /gene="rrf"
                     /locus_tag="ACGI3L_003825"
     rRNA            168..284
                     /gene="rrf"
                     /locus_tag="ACGI3L_003825"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            291..362
                     /locus_tag="ACGI3L_003826"
     tRNA            291..362
                     /locus_tag="ACGI3L_003826"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:323..325,aa:Asn,seq:gtt)
BASE COUNT          117 a           61 c           78 g          108 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc tatgtaaagt actaacttca
       61 attgatgaag tatatatcgt aaaaacaatt actatttagt acttcaaaac tattgacatt
      121 taaaaataaa gatgttaata taatacttgt cttataaata ggcaatatgt ggttataata
      181 gcaaagagga tacacctgtt cccattccga acacagaagt taagctcttt agcgctgatg
      241 gtacttggtg ggaaactgcc tgggagagta ggacgtagcc acgtgaatat tccaaggtag
      301 ctcaatggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc ccacccttgg
      361 agcc
//
LOCUS       DAYAKB010000216          327 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.223, whole genome shotgun sequence.
ACCESSION   DAYAKB010000216 DAYAKB010000000
VERSION     DAYAKB010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.223"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..>327
                     /locus_tag="ACGI3L_003827"
     CDS             <1..>327
                     /locus_tag="ACGI3L_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199466.1"
                     /translation="MGMLYSINLRIMGKSNIPLFSFKHLFNGEISPIVLALAFVFICK
                     VLLDLFLKTGLGYTLKGVGDNSQMIKSLGINIGSIKILGLMISNGLIALSGSLMAQFL
                     GFSDVNM"
BASE COUNT          104 a           49 c           53 g          121 t
ORIGIN      
        1 atgggaatgc tatactctat caatttaaga ataatgggaa aatcaaatat tcctctattt
       61 agctttaaac acttattcaa tggggaaata tctcctatag ttttagcctt agcttttgta
      121 ttcatctgta aagtcctttt agatttattc ctaaaaacag gtcttggata cactttaaaa
      181 ggtgttggtg ataactctca aatgattaaa tccctaggta taaatatcgg ttctataaaa
      241 atactaggac ttatgatttc aaacggactt atagctttat ctggtagtct tatggctcag
      301 ttcttgggat tctcagatgt aaatatg
//
LOCUS       DAYAKB010000217          309 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.224, whole genome shotgun sequence.
ACCESSION   DAYAKB010000217 DAYAKB010000000
VERSION     DAYAKB010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.224"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..245)
                     /locus_tag="ACGI3L_003828"
     CDS             complement(<1..245)
                     /locus_tag="ACGI3L_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFG9199467.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLV"
BASE COUNT          123 a           41 c           31 g          114 t
ORIGIN      
        1 actaataaaa attgtaaaaa tagtataaat ggtataccaa atgtaaattt aatgtgttta
       61 gttttatgtc taaaagaata cattccaatt atagaaccta tactacctcc aattactgct
      121 atagacataa gagtagcttc ttttattctc cattcgtttc taattgctct tttcttatct
      181 atgtacattg aaaagaaagc aatagaatta atcactataa aatatattag aataaaattt
      241 ttcacagtct tgcctccata aaaatatatt atacattata aaacaagata tttgttttgg
      301 aaagttaaa
//
LOCUS       DAYAKB010000218          277 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.225, whole genome shotgun sequence.
ACCESSION   DAYAKB010000218 DAYAKB010000000
VERSION     DAYAKB010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.225"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
BASE COUNT          109 a           18 c           23 g          127 t
ORIGIN      
        1 aagaattaat aaaaaatacg attacactac aaaattagaa tgtcaatgtt tataaatata
       61 aaataatatt ttttatttta attattacat ccatagtttc catttgttat aaaaaagtta
      121 ctatttattg aaaatttaga tatttttcta aaaattatct atgttaatag ttaaatttat
      181 gaacattttt tgtttttatg ttaggatatt tcttagaaat gaaatacttc ttaatttgat
      241 ttgatatgta tatttttata gctattttat tataaaa
//
LOCUS       DAYAKB010000219          270 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.226, whole genome shotgun sequence.
ACCESSION   DAYAKB010000219 DAYAKB010000000
VERSION     DAYAKB010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.226"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            3..>270
                     /locus_tag="ACGI3L_003829"
     rRNA            3..>270
                     /locus_tag="ACGI3L_003829"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           86 a           46 c           78 g           60 t
ORIGIN      
        1 ctggtcaagt tattaagggt gcagggcgga tgccttggca ctaggagccg atgaaggacg
       61 tgataagctg cgataagctt cggggagttg cacgtaaact ttgatccgaa gatttccgaa
      121 tgaggaaact cacttagagt aatgtctaag tatcattaag tgaatacata gcttaatgag
      181 gggaactcag ggaactgaaa catctaagta cctgaaggaa gagaaagaaa ttcgattccg
      241 taagtagcgg cgagcgaacg cggattagcc
//
LOCUS       DAYAKB010000220          251 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.227, whole genome shotgun sequence.
ACCESSION   DAYAKB010000220 DAYAKB010000000
VERSION     DAYAKB010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.227"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..>251
                     /locus_tag="ACGI3L_003830"
     CDS             <1..>251
                     /locus_tag="ACGI3L_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine rich domain-containing protein"
                     /protein_id="HFG9199468.1"
                     /translation="ILKPGKYKFECWGSSGGINNSSWHTDAKGGYSKGEITLKKQTTL
                     YVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQVMGTYYS"
BASE COUNT           82 a           34 c           51 g           84 t
ORIGIN      
        1 atattgaaac ctggcaaata taaatttgaa tgctggggtt cttctggagg tatcaacaat
       61 tcttcttggc atactgatgc taaaggcgga tattctaaag gtgaaattac attaaaaaaa
      121 caaactacat tatatgttta cgtcggcgaa agtggttttg cttcttcatc tacgagtaat
      181 aacactaaaa gtggttttaa tggcggtggt aaaggttatt taaatcaaca ggttatgggt
      241 acttattatt c
//
LOCUS       DAYAKB010000221          232 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.229, whole genome shotgun sequence.
ACCESSION   DAYAKB010000221 DAYAKB010000000
VERSION     DAYAKB010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.229"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..>232)
                     /locus_tag="ACGI3L_003831"
     CDS             complement(<1..>232)
                     /locus_tag="ACGI3L_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HFG9199469.1"
                     /translation="NVIQKIQQLVPPTHPVLGDGILVLTDIKSSPYPGASVVPDYCKA
                     TFDRRLLVGETREGVLAPIQALLDEMMKEDPE"
BASE COUNT           66 a           41 c           37 g           88 t
ORIGIN      
        1 aattctgggt cttctttcat catttcatct aataaagctt gtattggagc taatacgcct
       61 tctcttgttt ctccaactaa taatcttcta tcaaaagtag ctttgcaata atctggcact
      121 actgatgctc ctggatatgg agaagatttt atatctgtta aaactaatat tccatcacct
      181 aaaactggat gagttggagg tactaattgt tgtatctttt ggattacatt ag
//
LOCUS       DAYAKB010000222          225 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.230, whole genome shotgun sequence.
ACCESSION   DAYAKB010000222 DAYAKB010000000
VERSION     DAYAKB010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.230"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..>225)
                     /locus_tag="ACGI3L_003832"
     CDS             complement(<1..>225)
                     /locus_tag="ACGI3L_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycine-rich protein"
                     /protein_id="HFG9199470.1"
                     /translation="IIVAGGGGGSYSPYTGGAGGGLAGGTGYSANDRHRPGGTQYQGG
                     IGRVSTENGSFGKGCSAKDSTGEGGGGGWF"
BASE COUNT           59 a           78 c           34 g           54 t
ORIGIN      
        1 caaaccagcc acctccaccg ccttcgccag ttgaatcttt agcagaacac ccttttccaa
       61 aacttccgtt ttctgtgctt acacgaccaa taccaccttg atattgagta ccgccgggac
      121 gatgtctgtc gttagcacta tacccagtac ctcctgctaa tcctcctcct gcaccaccag
      181 tataaggaga atatgaacca ccgccaccac ctgcgacaat tatac
//
LOCUS       DAYAKB010000223          222 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.231, whole genome shotgun sequence.
ACCESSION   DAYAKB010000223 DAYAKB010000000
VERSION     DAYAKB010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.231"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
BASE COUNT          110 a           22 c           26 g           64 t
ORIGIN      
        1 aaagtacata aatttaaaaa tccagaaaaa tatacttaaa ttatgtaagt aaaagagggg
       61 ttgaatcagt tgaaaatgta atattagtaa atagtacatc aatcctatat accctgtaag
      121 caactctatt ttcatgtact aaaaatgtac ctattttatt aactgaaaag aataaattaa
      181 atgtaagtac ataagaagat agaaaaaatt aaaaacaaaa aa
//
LOCUS       DAYAKB010000224          220 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.232, whole genome shotgun sequence.
ACCESSION   DAYAKB010000224 DAYAKB010000000
VERSION     DAYAKB010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.232"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
BASE COUNT           94 a           27 c           34 g           65 t
ORIGIN      
        1 tactggtaac ttaaatattt cactaaaaaa aaacaaatgc aaagctagta ccaaaaataa
       61 atcagaaaaa agaggtgttg tagatgttac aaattaaaaa tctttcaaag agtttcccta
      121 atccatatgg tgaacctaat actatctttg aaaatttatc aatcgatata gaagatggtg
      181 aatttgtaag tatcataggt agtaatggaa ctggtaaatc
//
LOCUS       DAYAKB010000225          219 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.denovo.233, whole genome shotgun sequence.
ACCESSION   DAYAKB010000225 DAYAKB010000000
VERSION     DAYAKB010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.denovo.233"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            complement(<1..>219)
                     /locus_tag="ACGI3L_003833"
     rRNA            complement(<1..>219)
                     /locus_tag="ACGI3L_003833"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           42 a           64 c           47 g           66 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtccc
//
LOCUS       DAYAKB010000226        11804 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.101, whole genome shotgun sequence.
ACCESSION   DAYAKB010000226 DAYAKB010000000
VERSION     DAYAKB010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.101"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            147..464
                     /locus_tag="ACGI3L_003834"
     CDS             147..464
                     /locus_tag="ACGI3L_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9199471.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            614..1291
                     /locus_tag="ACGI3L_003835"
     CDS             614..1291
                     /locus_tag="ACGI3L_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199472.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(1619..2386)
                     /gene="aroD"
                     /locus_tag="ACGI3L_003836"
     CDS             complement(1619..2386)
                     /gene="aroD"
                     /locus_tag="ACGI3L_003836"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFG9199473.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3058..3894)
                     /locus_tag="ACGI3L_003837"
                     /pseudo
     CDS             complement(3058..3894)
                     /locus_tag="ACGI3L_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            3965..4633
                     /locus_tag="ACGI3L_003838"
                     /pseudo
     CDS             3965..4633
                     /locus_tag="ACGI3L_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            4760..5380
                     /locus_tag="ACGI3L_003839"
     CDS             4760..5380
                     /locus_tag="ACGI3L_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9199474.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            5536..6318
                     /locus_tag="ACGI3L_003840"
     CDS             5536..6318
                     /locus_tag="ACGI3L_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HFG9199475.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6443..7369
                     /locus_tag="ACGI3L_003841"
     CDS             6443..7369
                     /locus_tag="ACGI3L_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9199476.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            7383..7832
                     /locus_tag="ACGI3L_003842"
                     /pseudo
     CDS             7383..7832
                     /locus_tag="ACGI3L_003842"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8192..8599
                     /locus_tag="ACGI3L_003843"
     CDS             8192..8599
                     /locus_tag="ACGI3L_003843"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9199477.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            8601..8831
                     /locus_tag="ACGI3L_003844"
     CDS             8601..8831
                     /locus_tag="ACGI3L_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199478.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9221..9424
                     /locus_tag="ACGI3L_003845"
     CDS             9221..9424
                     /locus_tag="ACGI3L_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFG9199479.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            9502..9834
                     /locus_tag="ACGI3L_003846"
                     /pseudo
     CDS             9502..9834
                     /locus_tag="ACGI3L_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
     gene            9927..10559
                     /locus_tag="ACGI3L_003847"
     CDS             9927..10559
                     /locus_tag="ACGI3L_003847"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HFG9199480.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(10929..>11804)
                     /locus_tag="ACGI3L_003848"
     CDS             complement(10929..>11804)
                     /locus_tag="ACGI3L_003848"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9199481.1"
                     /translation="FNMEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFK
                     IKPLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITM
                     YGSPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVK
                     KSGIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKA
                     GEFTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDY
                     YLSNQKLKREEYRRL"
BASE COUNT         4260 a         1716 c         1796 g         4032 t
ORIGIN      
        1 caacagaagg cgttgataac tctgtacctt tagaatgtta tgaaatgatt aataaattaa
       61 ctgaaaaaga acaaattgca atgctagagt taataaagtg catcattaaa tacaaagaaa
      121 tataagtgag ggaaatagta acaataatga attatatagg taaaagactt aaagaagaac
      181 ggaaaaaagc aaatttaact tcaaaagaat ttgcaaatat ggttggagta tcgccttggt
      241 atataactca aatcgaaagt ggtaaaaaga atccaagtct taaaacattc ataaaatttg
      301 taaatatatt aaatatttct gcagatgttc ttataaaaga tattacttcc actggaaaaa
      361 catatttaga aaatgatata aatgaagagt taaaagactt aaattcaaga gaactaaatc
      421 tgatatcaca gattatagac atcataaaaa agaataaaat ataattcttt atattttata
      481 taaaaaaaaa ggttatttga aataaataac ctttttttgt ctttttgtgt taacattgtc
      541 ttatagtgct aatgagtact attagaccat gttctatggc cttattttaa tataaaacga
      601 ttggagatag gctatgattg tgattgaagg tagcgataaa tttaagattg caaaagaata
      661 tattgatgta gaatatactc tttttagcaa agtaactttt aggtatgaaa agttgaaatt
      721 taaagataat gctgaattgg aaaaaattaa gatgtttaaa tataaaaatg gctacatccc
      781 taataaatta aacctttctt ttggatatgg attctcttct tataaaaagc aaataattag
      841 agaaactgta gatactttaa gattgacaga aattttttca agcgagaaca tagaagatat
      901 taaatttata aaagatggta caaaaaaatt agaaattagc atagagaaag ttgtgaaatt
      961 taaacgtcga aaaaaaagaa attatgtttg ttgctattgc cctgatatgt atagagacat
     1021 aaaactcgac aaagaatcta tcaataagat atacaacaga aaaataaaaa tagaaagaga
     1081 agttaatatt tttgaagatg aggatgttat aataaacaag aaagtattga agtttccaaa
     1141 gtcttggaca aagaatatgc aaaaatattg gttaagtgaa aataagtatc ccatacattc
     1201 tactgtaatt gatgatgata gatataaatg ttgtaatgta caatatacaa aaaatagagt
     1261 gataatatta tattacatat ataaccatta atatacataa ttacaaaaaa ataatgacaa
     1321 atatacataa tacaaatata tcttctactt tagataaaac agttattatg aaaacttact
     1381 atctataaat aatagaaatg ctagtatacc atctataatc taatgtctag taggttttaa
     1441 tggcatattt taaatatgcc atagttgatt tataagattt tctatatcac tttcaaaata
     1501 cacactaaat agttgctttt cagatataat tgcccaattt aaattttact atctgaaaag
     1561 ttttttatat ttaatttata tcttcaaaaa taccgtctaa tatttctata taattaattt
     1621 aattaatact cttatgtaat agattaagta ctgaatttaa ctctttaaat gatatttgcc
     1681 ctggtgctga aacacttttt gcagctccaa aagtcaatgc agaaccaaat atttcaccac
     1741 acaatctact tataacaccc attcctgaca ttgacattgt tattattggt ctatctgcat
     1801 aaattttaaa catttcattt gtagcttcaa gtagcactaa cacatctttt tcattttgcg
     1861 gcataacagc tattttgggt aaatctgcgc ccaattcctg cattctacat aaacgagata
     1921 caatctcttc tttttttgga gttttattaa aatcatgatt agatataatt actttcactt
     1981 cttttttatg agcaaaatta actacttcat ctatgacctc atctcccata aataactcta
     2041 catctattaa atctactaaa cctgtattag aaatttcttt attcaaagta gtataataat
     2101 ctcttgatat taatttttct cccccttcta ctacacttct aaatgtgaat aataaaggga
     2161 tatcatgtat ataacttctt aattcataga gaacttcctt aacttcttta atattttcta
     2221 cattctcaaa aaaatcaact cgccactcta taatatccaa acatgcatct tttaactctt
     2281 tagcctcttt tataatatct tttttatttt tcccaataat tggtacacaa attttaggtc
     2341 taccttctcc aatagtaata ttttttactt gaacttttct tttcatattc tcctccataa
     2401 tcagaaattc tataggactt taaattctat tttctgcaca atttaattat acattaaaaa
     2461 tactatacat tataaaaata ctaatttaaa aataattttt attctaattc ttaaaacaat
     2521 cccacatatt ttagaaaagg tactctataa tatacaaaca cttctttttt acctaaattt
     2581 attttaacat cctataattt tcacaatatt ctttaaattt tactcatata aacaatatta
     2641 ttctggatgc taatagaatt aatctataaa tcatagtata attatgcaga aataactcga
     2701 atttcactac ttatgaagag attgaatatt aatgaatcta aatcatttgc attacttaag
     2761 agttttgact aaagttgaac accatacaaa agtagctact caattgttta taccccaacc
     2821 aagcttaagt aatgttatat agattctcga aaaagaattt ggtatctttt tatttgaaaa
     2881 acttatatta aatttgatta tcttttcata agttggtaaa tgtcgatata tcctgtatct
     2941 acaaggagta tcggcatttt ctttttggaa gatactttgc ataagttggc atttaaccgt
     3001 ataagaatgc catcaaaagt agtaaataag tagtaaactc tagtcatact actaggatta
     3061 taaccgttcc atttcagctc tcgaagaact aaatgaacca tgtgcataat agccaagcgt
     3121 catagtaatg tttttatgcc ccataatata ttgcaatata ttaggactca ttcctttgtt
     3181 agccatattt gtacagagtg tatgcctaaa ggtatgtggc gtaatctttg gtagcttgtc
     3241 ctcatgggtc ttattatact tcttgactaa cgctcttaac atgctttgat aatgagttgc
     3301 ttgttttggt aatccatctt gtttaagaaa taggaagttc tggtaaccat caacaatgat
     3361 tggttctgct ttagcgttct tacgccgttc cacgatacgt tcaaatgatt gataagctct
     3421 ttcagtcatt ggaatttctc gcttaccctg tgtggtcttt ggaacttcta cataatagcc
     3481 aatcttagta tcactcaaca attgatggtc taccataatg gctttatttt tcatatccaa
     3541 ttctaaagtc aaaccgcata attcagaaat gcgtagtcct gtttctaaga ggataacaac
     3601 atcatcataa tatttacaat aagtcttatc gctccccata aaggataata agcccatttc
     3661 ctgttctggt gttagagcga tttttggttc tgttgtatct tccaaaacat cacttaacta
     3721 aaaattaaat ggattctttc taatacagtc gtcttgaatt gccatgaaaa acgacgcttt
     3781 cagtgagcgc ttataattgt caatggattt ataagcacac ccatcttcac tcattcggat
     3841 agcccagctt ttagcgtctg ataatttaac catatcaatg ctttttgcac ctagtgggtc
     3901 attgatagta tctatatttt gatttataat ttatacattt ttttaaaaac agacttttaa
     3961 ctgtaaagaa tctatgtata aacttagcta tgttgtccgt gtatctacaa agaatcttga
     4021 cgagctaaaa aggcgttgtg atgaagtcaa agacttttac gacgacttat caatcaagct
     4081 cgtgcgtccc tttggggata tgttgggatt gcatggcgaa tttattcctg tcagcaaacg
     4141 ttacatcaat gattatattc aatatgtcac ttcggatttt ttggctggac ttggttttgg
     4201 agcgacacaa acccttggcg aacatgagga tatctatctt ggctacaatc tggacactgg
     4261 aaagaatgtc tatctaaaac ctgcccttgc tagtcaaggg gtaaagggtt ctattaccaa
     4321 tgcgttagcg tctgcgttta tcggttcatt gggtggtggt aaattattca gtaacaatat
     4381 gcttgtttac tatgcggtac tattcggcgg acaggcggtc atagttgacc ctaaagcaga
     4441 acgcggcaaa tggaaagaaa cgctaccaga aatagcccat gagataaaca ttgtcaattt
     4501 aaccagtaat gatgaaaaca aaggattgct tgacccttac gtcattttga gccgtaaaaa
     4561 ggattctgaa agtttagcga ttgatatcct aacattcctt actggtatct ccagtcgtga
     4621 cagtgataag tttttgcaga aaaatgacaa ctggaaaata ataatggaat agtttctatg
     4681 taaatatatt tttactatct tacctaacta attgaaagat gatataattt aatcaaagat
     4741 ttggtaagga gggatgaata tgcatttaat tgattttatg aatgaagata ttaaaaagaa
     4801 gcttgttaaa aaaacgtata aaaagaaaga gactattctt tttgctgagc aagaaaatga
     4861 atatgtaatt cttatgattg acggtattgc agaagcattc atcttaaatg tgaaaggaaa
     4921 catctcaacg attcatcttt atagaagtgg tagttttttt ggagaaatgg aacaatttaa
     4981 tgatgggaaa aaacccgttg aaattgtcgc tttcacagat tgtaatgtat ataaacttca
     5041 tagagatgat tttttaaact ggttaagggg agattttgaa gctacaaaat ttctgattcg
     5101 agaaatatct agtaaattag ttgtaaatgc tgaattaatt gaagaattat catctttaag
     5161 tgttaaagaa cgacttctga ggtgtatatc cttacactat tatagaagtg aattaaatct
     5221 gcttaccaaa aaacagcttg ctagcgaagt aaacgctcca attagaagca ttaatcgtgc
     5281 tataaatgaa tgtgtacaag aacatctaat tgcttatgaa aacaaaagat ttagtgtaat
     5341 taatcagcga gaggtattaa agaatcttcc tacaacataa gtataatttc aaaaaagtat
     5401 tgaataataa ttattcaatg cttttttatt tcgggtcaag tgacctattt ttttttattt
     5461 cttcattata taatactcct atgcataatt atgttggatt gatagctaat aaaagacagt
     5521 gagaggtgtt atattatgac taaaacacaa cagaaaatga tacaaaacgt attagaattt
     5581 tcaaaaagag atagtaggat aataggactt gcaattagca gttcttatat cacaaaatcg
     5641 ttagatgaat attctgattt ggattttctg attgtagcag atgataaatc ctatgaagaa
     5701 gttatcgaag agagattact tattgtggaa cagtttggaa cattagtttc tgcttttact
     5761 ggcgaacacg ttggagaacc tcgattgata atttccctct atgattcccc tgttcttcat
     5821 gttgatttta agtttacaac cttagatggt ttactagata gggttgaaga ttcagctatt
     5881 ctctatgaag aaaacaactg cataacagaa atttattcta aaaaagaagc atacttccca
     5941 actccagact tacagtggat tgaagataga ttttggattt gggttcatta cgcttgcact
     6001 aagattggac gtagagaact atttgaaaca attgattttt tatctttttt aagacaatca
     6061 gtacttgccc cattaataca gcttctctta ggtaaattac ctcgtggagt tagaaaaatt
     6121 gaattggacg caccccaata tattgaagca ttagaaaaga cggttgctaa ccatgaatat
     6181 aaaagctgtg ttaatgcatt gcaggctact atcaacctgt atcttgagtt aagagaggaa
     6241 ttatcacaaa gtcctattgt ccgaaaggtt gaagctgaaa gggttgcatt acagtatttt
     6301 caagatttaa tcaaataaac ccaaagtaaa aaaatattga atagtaaata ttcagtgttt
     6361 tttcattttt ggtcaaatga cctagattag ttgttgtaac aattctataa ttattttgaa
     6421 agtaacagta tggaggataa ctatgagtga tattttaagt agaattacaa ataaaattgg
     6481 ggataagaat atagttgata agttatcagc tctatcaaaa tcagatttga actcacttct
     6541 attagaagtg tttgatagac aagcaaatac tttaactgca actgatattc taaagtcata
     6601 ccaactaaat agatttacta tccctagcgg tatagatcca gaagaaattc atgctttgga
     6661 atcaaaatta ttgagaaaag cattcaatat ggatatcaag acgattatgc tttctccctc
     6721 tgccccatta ggtagctgta gcgtttttgg ctccgtagat caatataacg tagtaagtgc
     6781 tctacgaggg acagaaacac ttgcagaccc ctcaaatatg ttggcaataa ttattgctga
     6841 taaattaaaa agaaaagaag aaaataatac catacctatc cacatggcta ctactgctag
     6901 ggtaataaga gcacaaaatt ttgtaggtaa aggtttatat tcacattttg gcttatattg
     6961 tatggtttca tctggtatag atacagggtc ttacacttgt gaaaaaatgt tgttagaaaa
     7021 gcacttaaac tattataaag atatattaag tgaaatagaa aatgttcgtt tctctattat
     7081 tctacgcaaa agaaacggat acaaagataa tgacggattt ttcgacagaa tggttgaaac
     7141 tatcaaactt atttttccta atatagagtt atcaattcat aatgatgatg ttgataataa
     7201 ttattataaa ggtatcaatt tcaaattatc ggtcaaacaa ggaaatgaaa ccgttgaaat
     7261 agttgacggt ggatttgttg actggactta tcaaatgctt ggaaataaaa gagaacgctg
     7321 tttgataagt ggtattggct tagaaagatt tcttgtagct gtttcataaa aggagaagaa
     7381 aaatggaact tatagagtgg aattatgctt atattaccga tttagttgag tttgcgaatg
     7441 ataaagaaat tgcaaagaat cttcgtgaca acttccccca cccttatagg gagcaaaacg
     7501 ctagagattt tgttagtttt tgtttggcaa cttcagatgt taaacaactt agctatgcta
     7561 ttttttatca agaaagggct attggaagta tcagcctaac atttgaagaa gatacctcta
     7621 ttaataaaaa tgctgaatta ggttactggc ttgctaggaa ctattgaggc aaagggatag
     7681 caacaaatgc agtaaaagaa atatgcaaaa ttgcctttga aaaatacaac cttaacaaaa
     7741 ttcatgctaa tgtatattcc tacaatagag agtcaagtaa agtattggaa aaatgtggct
     7801 ttaagattga agaatactgt cacaattcat aataaagaat agaaacatga ttgattgcca
     7861 tgtatatagt ttaattcgac cgcaatagca tttattagaa ttaacctact ttttaataac
     7921 agaataagtt tttcccctct attaatttct tatgcatctt tgtattttta tgaaaagcta
     7981 gccaatgcat atttccatac atcaatatgg tggtggctta caaccaatat aaattaaata
     8041 cgttttaaag aatacacatt tttgccctat aggcagagtg tgtatttttt tctctttttt
     8101 ttgaaattta tcgaagattt aacgccctcc caccgtgata ggagtaagca aggttattta
     8161 actccttgcg atggaaagag ggtgaaatct tatggttgat gaaaagacaa ttgaacatca
     8221 attcgacagt ttctgtaaaa cagttttgcg taactatgct agagatattt atgacgaaaa
     8281 taaacgcaga aatgattatt tggtatctct cgaatctttg tcacttgcag aattaagtaa
     8341 attgagtatt ttagatgatt atgattctaa ctacatctgt atggtttctt acgactacaa
     8401 catacgaatt gaagatgtat taatggcgca agcaatcgga aaacttacaa aaagaaaaca
     8461 agatataatt ctactttcat tctttttcaa catgacaaat gctgacatag caacattgat
     8521 ggatttagca gaaaatacca tacattatca caaaacaaat gcactaaaag agttgaaaga
     8581 actcatgcag gaacattgaa atgaaaccta ctaaagaagt attacctttt acaattattt
     8641 tacttgctgt acatggcgat gtaaatgcaa taaacgtaat acttaaacat tttgaacact
     8701 atatcattcg tctttcacag aaaactttat ttgatgaata cggaaatccc tatattcatg
     8761 tagaagaaga aacaaagcga atgctaggaa caaaactaat cactgctatt ttgagattta
     8821 atttgtctta atctcgccct ctctccatgt atcaagctat ttggtacatg gagaatcact
     8881 aattatttgt ctataaaagc ccacaagcta ttgtgatttt ttataggcaa atcaatgccg
     8941 actgttcttt gacaactgaa taaagtagat agatacgttt gtgatacaga tagccaacaa
     9001 atactatacg ccatgacctt aatcaagaga gctactatat agtgatttgt gaataacctt
     9061 tggaacggtt gttttgccgt aacctgtacc acagtataat gatacacctg tatgacacgg
     9121 ttctgtccat aagaatggga ttggttgaaa taccaatgga gcttatcaaa gccatctatc
     9181 tacttctgaa ctacgaacat agaaaggagt gatacattat atgaacaata ctgatgtacc
     9241 tatttgggaa aaatatacct tgacgattga agaagcgtca aaatactttc gtattggaga
     9301 gaaaaaatta cgtaaacgtg ctgatgaaaa ccttgattct ggctgggtca ttatgaatag
     9361 caatcgcatt caaataaaga gaaaacaatt tgagaaaatc gttgatacac ttgacgttat
     9421 ctaatgaaat tgagccttat atgttataat attcatatga cgtatcaagc tcaattcggt
     9481 tattgagagg agcttcttat catgtcaact gaaaaaagac gagataataa agatagaatt
     9541 ttaagaactg gagagagcca gagaaaagat ggaagatacg catataagta tgtatattca
     9601 tttggtaaac cacaatttgt ttactcttgg aaacttgtac ctactgataa acccccaaag
     9661 ggaaaacgtg atgatatatc attaagggat aaggaaaaag caatacaaaa tgaccttgat
     9721 gatagcattg acactattgg taagaaaatg acagtttgtc agttatacgc taaaaagaat
     9781 ggactaagaa agaatatccg acttaacact aaaaaaggac gccattatct tatgaagatt
     9841 cttaacaagg agtgattctg tgaagagatg tattgtagta gtggaatagt caaaaacata
     9901 atatatatta aaggagagat ttaaatatga ctattccaag ttcaaataag gtatatccaa
     9961 gaagtaatga ttatcaaact gtatatctta aaaatgtaat aacaagggaa aatatagaag
    10021 ttggagatta cacaatatat aatgactttt ataatgaccc aagagatttt gagaaaaaca
    10081 atgtattgta tcattaccct ataaacaatg ataaattaat aattggtaag ttttgctcaa
    10141 tagcatgtaa tgcaaaattt ctaatgacta gtggaaatca ctcaatgaaa tcaaaatcca
    10201 catatacttt tcccatcttt tatgaagaat ggaaactcga tatcaaccat ataacggacg
    10261 cttgggacaa taagggtaac attataattg gaaatgatgt gtggataggt tatgattcta
    10321 taattatgtc aggtgtaaat attggtgatg gtgcaattat tggaacaaga gcagtagtta
    10381 ctaatgacgt tccaccgtat tctattgttg gaggagtacc tgcaaaaatt ataaaaaaga
    10441 gatttaataa tgatacaatt tcaaaattat tagaaattaa atggtgggat tggccatata
    10501 aaaaaattca atcaaacatt aagcatattc aatcaggaaa tattgataaa ttagtttaat
    10561 attttataat ttatttatat taaactttac tttaataatc attttataag agctttttca
    10621 aaatttgtat attattttaa tatatataaa tttaatacaa cattaaataa aataaaaagt
    10681 aaagttactt aataaaaagt tactttactt tttattattt aaattcctgt ttttattata
    10741 ataggtaaaa ttctattaaa ctagttcaca ttttcattat tattgatata ttatatatga
    10801 atataccatt ttgtttttta ataaaaaatc atgctacatc aatagtaagc aactattaat
    10861 gtagcatgat tttttgtatc taaataatct tagtatttac ctatcagtat agattgatat
    10921 atcaaaaact atagtcttct atattcttct ctttttagct tttggttact tagatagtaa
    10981 tcaatttcat caattagacg ttgtttatca tcaggtaata caccttttaa attagcataa
    11041 tttgatgcat gattacttct aaatacaatt ttttcattag catctatatt ctttatcatc
    11101 tctttaattt cttgtaacac agccttatcc tctagtattg taaactctcc tgccttaagt
    11161 aaatcgtaaa gttcagtatt aggttctacc attaaactaa gtacacccac ataatctggt
    11221 gaaattgctc ctagcatttt tcctgtatca actgcatgct gatgtgtttt tttagttcct
    11281 ccaagacctg ctattacagt ggctgataat ttaatcccac tttttttaac ttttctacca
    11341 acttttatta attgttcact actaaaacct ttcttaatat cttctaatac ttcattgctt
    11401 ccactttcaa gccctagata aatcatttta acaccaagtt ttcttaattc tttaagttca
    11461 tcatcagatt ttttctctat agatttagga gagccgtaca tagtaattct ttcacactct
    11521 ggaaaaactt cttttatata taaaataata tctcttaatt tctccattgg tattatcaat
    11581 gcatctccat ctgctaagaa tattctttct acatgcttat aatatcttct aaatatatca
    11641 atttcatttt ttattacttc tagtggcttt attttaaatt ttttagattt gtacatacta
    11701 caaaacgtac atttgttatg agaacatcct agtgtgactt gtattataag actataagcc
    11761 tcacttggtg gtctgtaaag tggcatatcg tattccatat taaa
//
LOCUS       DAYAKB010000227         5936 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.139, whole genome shotgun sequence.
ACCESSION   DAYAKB010000227 DAYAKB010000000
VERSION     DAYAKB010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5936
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.139"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..799
                     /locus_tag="ACGI3L_003849"
     CDS             <1..799
                     /locus_tag="ACGI3L_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9199482.1"
                     /translation="NDEEIILMGKGIGHNYKAGSELNKKDIEKIFVLHDENIKKSIIQ
                     LATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIAFAVRRFKEGIMIENHYL
                     FEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHFINAQQDNPYSDRNKRSA
                     KIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLANEPSREKIDFIYEQVQK
                     NCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILGELCENS"
     gene            1460..2152
                     /locus_tag="ACGI3L_003850"
     CDS             1460..2152
                     /locus_tag="ACGI3L_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199483.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            2149..3084
                     /locus_tag="ACGI3L_003851"
     CDS             2149..3084
                     /locus_tag="ACGI3L_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9199484.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            3232..4155
                     /locus_tag="ACGI3L_003852"
     CDS             3232..4155
                     /locus_tag="ACGI3L_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199485.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            4139..4909
                     /locus_tag="ACGI3L_003853"
     CDS             4139..4909
                     /locus_tag="ACGI3L_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199486.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            4919..5701
                     /locus_tag="ACGI3L_003854"
     CDS             4919..5701
                     /locus_tag="ACGI3L_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199487.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
BASE COUNT         1958 a          853 c         1123 g         2002 t
ORIGIN      
        1 taatgatgaa gaaataatat tgatggggaa aggcattggc cataattata aggccgggtc
       61 tgagttaaat aaaaaagata tagaaaagat ttttgttctt catgatgaaa atataaaaaa
      121 gagtattata caattggcaa cagaaataga tgcagaatat tttggtatag ctcaaatgat
      181 aattgcatat ggaatagaaa aatataactt aaaacttatg aaccatatat atttggcctt
      241 aactgaccac attgcctttg cagtgagacg ttttaaagaa ggtataatga ttgaaaatca
      301 ctatttgttc gaaatcaagg aatttaatcc aaaagagtat gatataggaa aatatgctat
      361 tactgttttt aaggaggttc ttggtttaga cctaccagaa gaagagattg gtaatatagc
      421 aggccatttt ataaatgcac aacaagataa tccttatagt gatagaaata agagaagtgc
      481 taaaattgta aatgctattt tgcaaatagt tcattatcac ttttctattg tatataataa
      541 agagtcattt tattatagga gatttgtaat gcatctaaag gccttttcac aaagatttct
      601 ggctaatgaa ccatcaagag aaaaaataga ttttatatat gagcaagttc aaaaaaattg
      661 taaggaagag tatgaatgtg tgaaaaaggt aggagcttat atgtataagg aatactccag
      721 agaattacca agacaagagg agttatattt gatgattcat attcataaga ttttaggaga
      781 attatgcgaa aatagttaga atatcttaat atgctagtaa tattataaaa aattaaaaat
      841 taactgcact ttaaatatga ataattgcat tacttaaggg ggttgtctta aaattgattt
      901 ttttaattaa atttgaagct caactccttt tttaaacctt tatatcatta caactttaat
      961 gtttatacga ctgtacttta gatgtatatc tactttttac atttctcaac atgcaaacct
     1021 accatttttt gcagtatgtt aattgaaata aaccattgag ttaaccctaa atttattctg
     1081 gacttatagg aatagttcca aagatacttt aaaatatttt ctggaataat tgcttatttc
     1141 acatatgttt tattgtgatg ttttgattta ataaattctt caactctgta tatagtaaat
     1201 gtattatcat gtttgtttta ttcaagcaca cttataatac gcttgatttt ttcacaatga
     1261 tgaaatatac taatgggtgt tataggtata agaatcgcat tacacttgaa gaagtaagtg
     1321 ataaatgagg tataaatcct catatgataa actactattt cattgaggaa catattctaa
     1381 gtgatgtcaa gatactacaa tatgactaaa ttcctagtga taaaaaagtc tacgaatgag
     1441 tgtagaaagg ggaactaaga tgaataaagt tttaattata gatgatgata aagatctttg
     1501 tattttgtta aaaaagagta tttcaattga acagattgaa gcaaactatt gccattctgg
     1561 gagagatgga ctggttgaac tttcaaaaca agattatcag ttagtagttc tagatgtgat
     1621 gatgccaggt atggatggtt ttgaaactat ggaacaaata cgaaaatata gcagtattcc
     1681 catcttaatg ctgacatcaa aaagcgataa ttacagcaaa gtgcatggat tgcgagctgg
     1741 tgcagatgac tatctaacca aaccatttga aattacagaa tttactgctc gtgtactgtc
     1801 tttaatccga cgttacaccc gttttaatcc aaaaaatgag gagccacagc aactttcttt
     1861 caaaggtttg ttgattgacc ttgaccagca tacagttact accaatggcg aacctatgtt
     1921 gcttccaccc aaggaatttg gtgtacttct ttactgtgca aggcatcagg gtaagatttt
     1981 gacaaaacag cagatttatg aagccgtgtg gggtgagcca tatgtatatg atgacagcaa
     2041 tatcatggct attatcagtc gcctaagaaa aaaaattgaa ctagacccat catctcccat
     2101 ctatttgcaa acaataaaag gaattgggta tcaattcaac acggaggtat gaaaatggat
     2161 gaacaaacga taattctttt cttactcttg ctgtcgattg gtctactttt tctttccata
     2221 tttgcttttt ccaagcttgg gcatatttac aagcgcctaa aagatataga ggagatactg
     2281 gctgatgtac aaattggaga cgaaaatcgt aaaatactaa ttaagccatg tgatgttatg
     2341 gctccattgg tttatcagct taatgagatt gtctacgatt atgaaaataa gttactttct
     2401 ctgaaaaagt cggataaagc tagcaaacaa cttatgacaa gtttatctca tgatgttcgt
     2461 acaccattaa caactctgat tggttatctg gatgctgtac acagtggtat agttatcgaa
     2521 caagagcggg aggaatacct tgaaatcgct aggcgtagag cctacgacct caaggattac
     2581 attgatgttc tttttgactg gtttcggttg aactctgatg aatttacgct gtcaatagaa
     2641 tctgtggaaa ttgcagagtt gtcacgcaat attttgaaag actggattcc tatattccat
     2701 gaaaagaaac tgaattttga aattgatatt ccagaaaatc gactaatggt aaacctcgac
     2761 ccagatggat attcccgtgt ggtcaataat ctggttcaaa atgttcttgc tcacagtaag
     2821 gctcggcaaa tcaagattac catgagtgag gattccagaa tggtattact ccgtgttgag
     2881 gatgatggtg ttgggattgc cagagaaaat ttaccacata tttttgagcg actgtataag
     2941 tgtgataaag gacgttcaga aaaaggaagt ggtcttggtc tatctattgt cagtcaaatg
     3001 gtggagcgaa tgggtggtca ggtttccgta gaaagtgaga ttggaaagta taccgtattt
     3061 acagtgagct taccattaat ataaaattgt ttttccccca tgtgacatgt atacacatgg
     3121 ggattttttg taagttataa agttgcaagg ttaatacaag gttgttgcaa ggttaatgta
     3181 agattgaggt ggtatgataa ctttaataaa caaaggaggc ttttattatt tatgaataat
     3241 ttaattattg aaacaaaaaa tctcactaag caatatggtg ctcaaaagag cgtttctaat
     3301 ttgaatattc acgttcagaa aggtcgcatt tacggattgc taggaagaaa cggtgcgggt
     3361 aagacgacaa ctatgaaaat gttattgggt ctaacaaaac caactactgg agaaattaaa
     3421 atatttggtc aggacattca caataacgag aagaagcttc ttcctcgaat tggatgtttg
     3481 attgaatcac cagggtttta tcctaatctg acaggaacag aaaatctcaa aatctttgca
     3541 aggcttagag gaataccaaa aaaaaatgca gtagaatcag cactggatgt agtcggtttg
     3601 ccaaacaatg acaaaaagtt attttctcaa tactctcttg gtatgaaaca gaggttggcg
     3661 attgctcttg ccattatgca tgacccacaa ctgttgattt tggacgagcc tatcaatgga
     3721 cttgatccta ttggtattgc agaagtaaga acgtttattc gtgatctctg cacagaacga
     3781 ggtaaaacta ttttgatttc cagtcacatt ctttctgaaa ttgccttgtt ggcagatgac
     3841 attggcatta ttgaccatgg tattttgttg gaggaagaaa gtcttgccca attagaagaa
     3901 aaaaacagta aatacataca ttttgctgta tctgatgcag cacaggcagc aaggcttctg
     3961 gaaacccaac ttaacctgaa aaatttcaaa gtagcagata attacaatat tatgctatat
     4021 gatacagatg tttctgttgc agaaataaat cgtgctttca ttctaaacaa cattgaggta
     4081 tcagaatctc atttatgcga agatactctt gaagattact tcaagaaagt aacagggggt
     4141 gaaggaattg cttgatataa tttcatgtga attttcaaaa ctcaagcggt taaaatttat
     4201 actgatttct attttaggtg cttgcttatt tccaattccc gcaacaattt tgattgcaaa
     4261 ggacaacttg ccctttgagc aattgttcaa attagttgtc aattttggat attttttgct
     4321 attaccaatt gtattaagta ttgttgctag ccaactattt tttatagaaa gagataatga
     4381 tgtattaaaa aatcttgcaa cagtgccagt gcaaaaagga aaactggctc tggcaaaatt
     4441 ggctgtgttg ctgtttatat cattgttcta ctctgttgca gggttaggag ctactatcat
     4501 tggaggtttc attgttggaa tagtagaggg ggttgctgta aaattaggaa tgagcattgc
     4561 ttttggaatt atgttttttg ttactgtact tcctgttgtg gtactcattg tatatttcaa
     4621 tcgcagctat attttttcta ttatactttc ttttgtatat gctattttca attttagtat
     4681 atccttaaat attatcaatt ttgaaccaaa taacccaata ttaagtgtat tacctgctcc
     4741 tgttataatg cgttggtgga tggcattttg gggagatccc actggcgaat acacggcact
     4801 tagacagcca tatttgctct caactcctgc ttgtgtaggt attttatgtt tgataaccat
     4861 tatagcagtc ctgctgattt gtatgatata caaaaagcag gagaattagg aggtatctat
     4921 gcttgatata attactacag aatttcaaaa aataaaaaga tataatattc tatggattgg
     4981 tgttgttgct gttctgtttt cagcactatt ggcagttttt caggttgtaa gttcacacgg
     5041 cagtgaccct ctaacgtatg agagctttgc aaacggagtt atctggaata atttcagtct
     5101 tagttttcca tttgggatta cacttattgg aggatatctt attaaccgtg aatatacaga
     5161 ccaaacctta aaaaacatcc taactgttcc tatttcatta cgcaaattgc tagtgggaaa
     5221 attaattgcg gttggaggaa ttactgtatt gttaagtctt ttcagcttct tatgcacatt
     5281 tattttgggg ttgttgtttt gcaatatcaa tatatctgtt acactcgttg taaaatcctt
     5341 agttcagatt ttgtctgtta atctgtattg ttatgttgct gttttgccga ttattgctta
     5401 ttttggtcgt aaacaaaatg catttctgac gggtgtaggg attgcatttg tatacggttt
     5461 ttgtggtgtg tttgttgctg gaagaaatct gacagacttt tatccaatca cagcaggtct
     5521 tggtctagtt ggatacaaca atggtgctgg tactgtttat cagccactta tcggtgctat
     5581 gactttgatt gtaattctaa tcttgacaac tattctactt gtatttacac ctaattatga
     5641 taaagttatg accatatcta agaaaaaagg gataaagcat aaaaagtatt ctcataaata
     5701 acataaatat tgtttctatt atttaagttg ctagacagtg aaaagaaaaa atctgtcgta
     5761 cagtgtctat atgctcatgt attcaagaag ctacagtttt gatttttcat aactgtagct
     5821 tctttttgta tttattaaat cacgactatc ataatacttg caataggtat agcgacaaga
     5881 gagagtactg tcatatgtgt tttatatatt acattaagta tattctaaaa tatatg
//
LOCUS       DAYAKB010000228         5230 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.147, whole genome shotgun sequence.
ACCESSION   DAYAKB010000228 DAYAKB010000000
VERSION     DAYAKB010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5230
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.147"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            191..376
                     /locus_tag="ACGI3L_003855"
     CDS             191..376
                     /locus_tag="ACGI3L_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9199488.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            369..1070
                     /locus_tag="ACGI3L_003856"
     CDS             369..1070
                     /locus_tag="ACGI3L_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9199489.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            1072..1995
                     /locus_tag="ACGI3L_003857"
     CDS             1072..1995
                     /locus_tag="ACGI3L_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9199490.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            2152..3075
                     /locus_tag="ACGI3L_003858"
     CDS             2152..3075
                     /locus_tag="ACGI3L_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9199491.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            3068..3805
                     /locus_tag="ACGI3L_003859"
     CDS             3068..3805
                     /locus_tag="ACGI3L_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199492.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            3816..4589
                     /locus_tag="ACGI3L_003860"
     CDS             3816..4589
                     /locus_tag="ACGI3L_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9199493.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
BASE COUNT         1763 a          791 c          940 g         1736 t
ORIGIN      
        1 gtttcatttc ttatcaccat tttagcataa aaggatataa gctaaaattg attttttaat
       61 ctccccattt taagtaaaac catgcaccat tttatcacta caaaattaag agtactactt
      121 actgatattt cttgattttg ttcgtctata cgtatataat atatgctgat aaattatgag
      181 gaaaggatga ttgaaatatg gatgcccaga agtagcaaaa aaatggggta tttctgaaag
      241 aagagtacaa aaactatgtg aagaaagtcg cataccagga gtttcaaaac tcgggtatat
      301 gtggctgata ccaaagaacg cagaaaagcc tgttgatggt agaacaaaaa gaagaaagga
      361 agtacaatat gaatagcgtt ttgattatag atgatgacaa agaactttgt gctcttatga
      421 aaaaatgtgt tgagcaagaa aatttatctg ctattactgc acattgtggt gcagaaggtc
      481 tacatttggt cgataaaaat agacacacac tctctcttgt aattttggac ataatgatgc
      541 cagatataga cggttttcaa gttctgaaaa aaattagaga aacaagtaat attccagtaa
      601 ttatgcttac tgctaaaaat gacgaggatg ataaagtttc cggactacgt ttaggtgctg
      661 acgattacct aacaaaaccg ttcagcataa acgaacttat ggctcgtgtc aattctctta
      721 ttcgtcggta tactatgtta aaccctgctt ttataacaga cacagattgc ataataataa
      781 atggcatgat tattgacaag acaaaccgaa ttgtttctgt caataatatt cctgttcaac
      841 ttacaagcaa agaatttgat ttacttgctt ttctggcttc taataaggga cgggtgttta
      901 ccaaaaaaca gatttataca caagtatggg aagaagaata tgcttttgac gatagtaaca
      961 tcatgtcttt catcagtaaa ttgagaaaaa agattgaacc agaccccaac catccatttt
     1021 atattttgac agttcgtggt gtcggttatc gttttaataa ggaggcttaa catgaataca
     1081 agtgtctatc tgcttttgat attggttctt agcctgatta ttatagcgta ccttgtttct
     1141 gtcctgctac gtgtccgaat acaacttaca cttataaaag atgctttaga ggatataaaa
     1201 aatggaaacc ttaatcgacg tattttaaca gatgaaaacg acattacaaa acaaatttgc
     1261 tatgatatta acgaaatagc aatcaatagc caatttcaac ttattcagca aaaacaatca
     1321 gaacaagcct acaaacagct aatgacaagt ctctcccatg atgtaaaaac tccacttgct
     1381 tctttggtcg gttatttgga agcagtagaa agtaaaattg ttgtaggaga ggaaaaagac
     1441 gagtatatcc atgttgcgtc taataaggct cattacttaa agaattttgt agaaaatcta
     1501 tttgaatggg taaaattgga ttctaaggaa caagtttttc attttgatat ttttgacttg
     1561 aatgaattat cccgtaatat tatatctgat tggatacctg ttttagaaag cagtcatttt
     1621 gaatatgaat ttgatatacc agaaatagag tacttcttac gtatagacgc aaatgcatat
     1681 acccgtatca ttaataacct attacaaaat attattaccc atagtagtgg caacaaaatg
     1741 acattgagaa tttttgaaaa caaagagcaa gctcaaatta taataacaga taatgggaaa
     1801 ggtatatctt cagacaatct cccacatatt tttgaaaggt tgtaccaatg cgaccattca
     1861 cgagcttcaa agggaaatgg tttaggcttg gcgattgcaa aggaacttat taacgctcat
     1921 aagggaaata ttaccgccaa cagcactccc ggtatgggaa cagaatttac aatattgctt
     1981 cctaaagccc tgtaaaagta cgaggctttc ttactctaaa acaagataaa agcaagatta
     2041 tggcaaggtt ttggcaaggt tcatgtttta taattctaat tgtagttgat tttgacgttg
     2101 tatcaactat cttttgtaga aacaaattta ttaaaagtga ggaaattata tatgaatgat
     2161 tttgtgattg aaacaaagca acttacaaaa atttatggga atcaaacagt agttgacaaa
     2221 gtcaatctcc atgcaaaaaa aggccgaata tatggtctgt taggacgcaa cggagctggg
     2281 aaaaccacaa ttatgaaaat gattttagga ttgacttcaa tcacgtatgg cgaggtagat
     2341 gtatttggag agaatattaa gggacgtgaa aaacaagtat atccccgtat cggtgcaatt
     2401 atcgaaacgc caggatttta tcctaatctg acaggaacgg agaacttgga gatttttgca
     2461 aaactgcgtg gtacagccgc ccctaattct gtaaaaagag cattggaaat tgtaggctta
     2521 ccttataaaa ataaaaagct gtttagtgaa tattcacttg gcatgaaaca gcgacttggt
     2581 attgccaacg ctatcctgca tgacccagaa ctgttagttt tagatgagcc aaccaatggt
     2641 cttgacccta ttggtattgc ggagatgaga aagtttatta gggacttgag cgttgagcat
     2701 ggaaagacaa ttcttatttc cagtcatatt ctttcagaaa tctcattgtt ggctgatgat
     2761 attggaatta tcgaccacgg tgttcttttg gaagaaagta gtatgagtga actagaaaag
     2821 aaaaacagta aatatatcct gctacaagtt tcagatattc cgaagacatc acttatttta
     2881 gagcgtcaat ttaacacgaa ggattattcc gttcaagatg actacacgtt acacctttat
     2941 aacactaatc tggatatggg tgaaatcaat aaagcacttg taatgcagaa tgtaactgtt
     3001 attagttctc aactttgtaa tgatacttta gaggactact ttaaaaaaat cacaggagga
     3061 gagggcattg cttaaactta ttcaaacaga atttcttaaa ctgcgtcgta ggaaacttat
     3121 ttggctgatg ttgttgtctg ctctcattat gccgtttttc gcactactat acttcaatta
     3181 ttttggtaaa acaggtgttg agccaataaa gttttataaa tggtctgcat ttggttatac
     3241 actttggatt attttgcctg ttgttttggg tatattttgc accatgctta tacacgaaga
     3301 aaaccagtat gatatgctca aacagctttg gattgtacct attagtaaaa tgggatactt
     3361 ttttagtaaa tttttcgttg ttttgattta ctctatttgt tttatgctga ttacagccgt
     3421 tgcttctgtg ttatttagtg tactttctgg atatgtcgta tttagctggg caagcatttt
     3481 atatttgttg aaaaaatgtt tagaaattgg tgtaatcact gcttttgtaa tgttgccgat
     3541 tttggcaatc gctacatctc aaaaaggata cattctccca atttgtatca cattggtata
     3601 tgccttttcc ggttttgtta taatgacaat aaatatgtat ttacacccat tatccagtat
     3661 gggagttatt atcatgagaa ataaagacat tccaggtctt atattttcac aggaaattaa
     3721 tgtcccatta gcatttcttt gtatttgtat ttggagtatt gtatcagtat tgtttgcaaa
     3781 cactgcacta ggaagaagaa agtgaggtgt agataatgtg gaaattactt tgggctgaat
     3841 gtcaaaaaat tcgtcgttca aaaattgttt ggattacagt ttttgcatcc attatgatag
     3901 cagtcatagt ttttgcagga gggcaggatg tatataatga cccagattta cattatggct
     3961 taaagagcgt ttatgacggt tcacggtata tagacaatgc aggttggtat atggacgcag
     4021 tacaaccttg gtcaactttt tttgttcttc ctgctgtcat tgccctatta ggaagctata
     4081 ttatttgtcg tgaagaagag gaggacacta ttaaatccct gcgtcttatt cccataaatg
     4141 aaacaaaatt aaccatagca aaaatgatta ttacttttat attcagtata cttctttatt
     4201 tgttactctt tactataaca tttttgactg aatccgtttt acatttttcc gatttatcga
     4261 caaaactggt tttaagttgc atgaaagagt attttcttga tggcataggt gtattctttg
     4321 caatttctcc cattattgcc ttggtatcgc gcatgaaaaa aggatattgg cttgcattag
     4381 tattcacaga agtttattct attgctggac tatttgcggg tatgtcaaat gtcttacaaa
     4441 ccttttttcc tattgcggca atatttaata tttctggata ctatataact actggagaaa
     4501 aaattatggg gagtatcata agtttattac tttgtgcctg cctttctgca tttatactta
     4561 aagggctaaa acacaatgaa aaaaattgaa ataggtatat caaaatgaaa aagataaaaa
     4621 aactgattat tctaattgta ttcttgtttc tttttggcat gttacactgt tatactgaat
     4681 ggaaattcaa caataaccca cctaaagggg taatagaaag aataaatgaa tggactgata
     4741 agattggact ggattagtaa cttatgttaa ttatagtgaa tgtaatatta gcaagttatt
     4801 gtttcgtatt ttaatactat aactttaaat atttggtttt aatcttccaa acgaatataa
     4861 aaaaactgtc acagaggcaa catatttttg aatatttata aagtggtagt tttgattttc
     4921 aaagctgccg ccttttcttc tatataagca aacttatcct caacaaagtg taaaacatgg
     4981 tacattttaa gaaaaaagta ccacagacac aagcaataaa agaaacgccg agaacctaca
     5041 aaaacgtagt gcttatgcag atttacgacg ccttctattt tctcaaccgt cttaatgacc
     5101 ttgtacaaaa gaaatttttc taatattttt tataatctta tcttgtgatg ttttttatgt
     5161 ataaatgact taataacaaa tccaataaaa attatggata ttggtataat tagaacgagg
     5221 aatttataat
//
LOCUS       DAYAKB010000229         4684 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.153, whole genome shotgun sequence.
ACCESSION   DAYAKB010000229 DAYAKB010000000
VERSION     DAYAKB010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.153"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..168
                     /locus_tag="ACGI3L_003861"
     CDS             <1..168
                     /locus_tag="ACGI3L_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9199494.1"
                     /translation="QFYRLDTSRNSNSGRAGLGLAIAKEIVELHNGTITAHSENNIII
                     FKVIIPIVGNL"
     gene            429..1529
                     /gene="vanG"
                     /locus_tag="ACGI3L_003862"
     CDS             429..1529
                     /gene="vanG"
                     /locus_tag="ACGI3L_003862"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HFG9199495.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            1526..2332
                     /locus_tag="ACGI3L_003863"
     CDS             1526..2332
                     /locus_tag="ACGI3L_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9199496.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            2350..4488
                     /gene="vanT"
                     /locus_tag="ACGI3L_003864"
     CDS             2350..4488
                     /gene="vanT"
                     /locus_tag="ACGI3L_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HFG9199497.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
BASE COUNT         1709 a          527 c          818 g         1630 t
ORIGIN      
        1 caattttaca ggttggatac atctcgtaat tcaaacagtg gtagagctgg gttgggactt
       61 gctatagcta aagaaatagt ggagcttcat aacgggacaa taacagctca tagcgagaac
      121 aatataatta tctttaaggt tattattccg attgtaggaa atttgtaaga atttaagtat
      181 aaaaaaatag gaaattcttt aggataaata aataaagagc actcttgtta ttgatataat
      241 tactgtatca aaacaagagt gcttttattt tgatacagta attatatcaa tagaaaaatg
      301 tgaaaatata ttatgtggaa cagatgcaat tgtaagtgaa ggttgattgg atttgaaata
      361 gaaaaagtat tttaacatgt ttctgtagat tgtataaaaa taaataaatc aacaaaggag
      421 aatcaaagat gaataataaa aaaattgcag ttatatttgg tggaaactca acagaatatg
      481 atgtatcatt acaatcagct tttgcagtac ttgagaattt gaatacggaa aaatatgata
      541 ttataccaat tggaattaca agggagggta attggtatca ttatattgga gattataata
      601 atatccagaa taacacttgg tttgaaaggg atactgatat aattccagtt attgtttcgc
      661 agaaccgtgt caaaaatggt attattgaat ttttaattcc tgatgctgtt tctcagaatc
      721 atattccaaa tagtgctatt gaatcatgtg aaaatgatat taaatacact aaacttgatt
      781 ttgtgtttcc tgtactgcat ggaaaaaatg gagaagatgg aacagtgcag gggttatttg
      841 aattggcagg tatacaggtt ataggatgtg gtactctttc ttcagcatta tgtatggaca
      901 aagacaaatc acataaactt gttcattcag aaggtattaa agtaccaaaa tcaatattac
      961 taaaatactc agataaattt aatgtggctg aactgtcaaa agacttaact tatccattat
     1021 ttataaaacc tgtgcgtgca ggttcatcat ttggtattag taaaatttat aaaaaagaag
     1081 agttacaagt agcagtagac ttggcttttg aacatgataa tgaagtaata attgaggaaa
     1141 atattgatgg ttttgaggta gggtgtgcag ttttaggaaa cgatgactta cttgttggaa
     1201 gagtagatga aatagaattg tcaaaaggat tttttgatta tacagaaaaa tatacattga
     1261 aaagttcaaa aattcatatg ccagctagaa ttgatttgga ttgtgagaaa agaatacaag
     1321 agacagcaaa aattatttat agaactcttg gatgttctgg atttgctaga gtagatatgt
     1381 ttttaactcc atctggtgaa attattttta atgaagtcaa tacaattcct ggctttactt
     1441 ctcatagtcg ttatccaaat atgatgaaag gtattggatt gtcttttgaa gaaatattgg
     1501 acaagataat tgaggtgtac ataaaatgat gaataatatt ttattagata aaaataaaga
     1561 agataaaatg acaaatacta tcttattgac taaagataaa gtttatgatg ggaatctaat
     1621 tctagtaaat gcttttttac cagttaaaac atctgaagat atagatttaa ttcctgtaga
     1681 tacaaggttt ccaagtattc ttatgaaacg tgaagctaca aacattttac aaaatatttt
     1741 aaaaagtata tgtggaataa atgaaatagt acctgtaagt ggatatcgta ctgcagagga
     1801 acaacaagat atatattcaa gttctctgcg tgacaatgga aaagacttta ctaaaaagtt
     1861 tgtagcactt ccaaatcaca gtgaacatca gacagggctt gctattgatt tagggttaaa
     1921 gaaagaagtt atagatttta tctgccctga atttccttat aatggtattt gtaatgagtt
     1981 tcgtaaggca gcactacatt atggttttat agagcgttat cagtgtaaaa aagaagaaat
     2041 aacaggaata tctcaagaac catggcattt tcgttatgtg ggatatccgc attctgagat
     2101 tatcaataaa atgaatctcg ctcttgaaga atatatagaa tatattaaga gattttcgta
     2161 tacaaattgt ttaaaaatag aagataaaga aaaaattata gaaatctttt atgtgcctat
     2221 tcatactaaa gaagaagtga gaatctctat acctgaacaa tgtgtatatc aaatatcggg
     2281 taacaataag gatggtttta ttgtgacatt ttggagaaat agaaaggact aagaaatgga
     2341 ggaacaagaa tgattaggaa taaatcttat gcagggcttg attattttag gattatagct
     2401 gcattactta taattgcaat tcatacatct ccattattat catatagtaa aatggctgac
     2461 tttgtgttaa ctagtataat tgctcgtatt gctgtgccat tcttttttat gctatcaggc
     2521 ttttttctaa tttcaacata taattataat tgtaataaac tgaaatcttt tctaaaaaat
     2581 gtattattta tttacgggat agctattgta atttatattc ccttaaatat ttacactgga
     2641 tatttttcca tgaataattt agtgcccaat attattaagg acattgtatt tgatgggact
     2701 ttatatcatt tatggtatct acctgcatca attattggtg caagtattgc atactttctt
     2761 gtaaaaagac taggtttaaa gtactcacta gtaatcacta ttgttattta tgtaattggt
     2821 atgtttggtg atagttatta tggtttttta gaaaaaatac cactattaaa gaatttatat
     2881 gggtatattt ttgaagtatc agattataca cgaaatggta tattttttgc acctgtattt
     2941 ttcatacttg gtggaataat atctaataaa tctaattata tgtcaactaa aaatagcttg
     3001 attggatttc ttatatcatt cttacttatg ttatgtgagg gaatgttttt acataaacta
     3061 ggggtacagc gtcatgatag catgtatatt atgttattgc catgtatgta tttcttattt
     3121 acagccttaa catttttgaa aggttctcga gctaggttat tgcgaacatc atcattaatt
     3181 atttatatta tacatcctat gatgattgtt gttattcgta tgttttctaa aatattcgga
     3241 atacaaactg tcttggttga caatagcctt attcattata tagtggtaag tatagcatct
     3301 tttatagctt ctataattat tatattgatt cttaaacctc taaaaaaaga cttgaaagga
     3361 gaacataagg taaataccaa tagagcttgg attgaaattg atttaaataa tttggaacat
     3421 aatgtaaaga tgatacaaaa agctatgcca gaagattgtg aattgatggc agttgtaaaa
     3481 gctaatgcct atggtcatag tgcttttgaa gtagcgactt gtgcaaacca aataggtgta
     3541 aaagcatttg cagtagcaac aatagatgag gggattgatt tacgtcgata tggaatacta
     3601 ggagaaatat tgattcttgg atatactaac ccaataaggg caaaggaact tcataaatac
     3661 aatcttacac agagtgttat tgaccttaat catgctatct ctttaaacaa acagaaatac
     3721 aacataaaat cacacattaa aattgataca ggtatgcaca gactgggttt tgatgttaat
     3781 gatgtgaggt caattttaaa ggcatttaaa ttaaaatact tagatatatg tggcatattt
     3841 acacacttgt gtgtttcaga tagtctgaaa gatgaagatg tagactttac aaataaacaa
     3901 attgaatgtt tttataagtt aattgatttt ctgttaaaaa aaggtataaa aattcctaaa
     3961 gtacatattc aaagtagtta tggttttttt aattatccca atcttaagtg taattatgta
     4021 agaattggaa ttgcattata cgggatatta agttctccaa atgatacgac taaattgcaa
     4081 cttgatttac gacctgtttt atccttaaaa tcacaagtaa ttcttattag aaaaatacaa
     4141 aaagatgata gttttggata tggaagagtc tttattgcaa gcagagatag cgtaattgct
     4201 atattatcta ttggctatgc cgatggtata cctagaaatt tatcctgtgg aaaaagttac
     4261 gtaataataa atggttgtag agcagcaata gtgggtcgaa tttgcatgga ccaacttgct
     4321 gttgatatta cagatatacc taatgtagaa gttggtaata cggcaataat aataggaaga
     4381 gataatttat ctgaattatc tgcttctgaa gttgcaaata actcatgtag tatatcgaat
     4441 gaattattga gcagagtagg aagaaggtta aatgttataa agaagtaact caattaaata
     4501 gtaatatttg ttgtactgtg taatttattt tactctgact agacattttt agtaatatta
     4561 tgtctaatat atatttttta taacttacat gacaatttaa gttataaaaa ggtgatgttt
     4621 cagattttta ttttgaaaca tcaccttttt tgttataata tataataaaa taattatacc
     4681 ttaa
//
LOCUS       DAYAKB010000230         3786 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.169, whole genome shotgun sequence.
ACCESSION   DAYAKB010000230 DAYAKB010000000
VERSION     DAYAKB010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3786
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.169"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..1688
                     /locus_tag="ACGI3L_003865"
     CDS             <1..1688
                     /locus_tag="ACGI3L_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9199498.1"
                     /translation="KNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKP
                     IWDILISLNPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNE
                     EIDKLYSYTGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFI
                     EVEEDEVTFRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPAL
                     SDGINEELGSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIA
                     TGSRNFIPPIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRL
                     KGLEVVVVEAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVF
                     KDGDSVDCDMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVG
                     NISLAIWPSSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEIS
                     SKDEGQRIYKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            2122..2823
                     /locus_tag="ACGI3L_003866"
     CDS             2122..2823
                     /locus_tag="ACGI3L_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-G-Cd"
                     /protein_id="HFG9199499.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            2873..>3786
                     /locus_tag="ACGI3L_003867"
     CDS             2873..>3786
                     /locus_tag="ACGI3L_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9199500.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIF"
BASE COUNT         1436 a          380 c          714 g         1256 t
ORIGIN      
        1 aaaaaaatag caactataaa gtaaatttat ttgatgtaat agagcataag caagaagata
       61 ttttggcaaa aatagcagta tcacaaggtg tattatttgg aacaccaaca atattaggag
      121 atgcgttaaa gcctatatgg gatatattaa tatcgttaaa cccagttctt catggtggaa
      181 aagttgcttc agtatttggt tcatatggat ggagtggaga aggtatagaa aatgctatgg
      241 agagaataag tcagcttaga atgacagcag taaaaccttt tgctgttaac tttaaaccat
      301 caaatgaaga gattgataaa ttatattctt atacaggtaa attcctagat aagttaaatt
      361 ctacttttgg aagtaaaaag aaaactaaga aatttaaatg tgtaatttgt aatgaagttt
      421 ttgaaggtga tagtgctcct agtgtatgcc ctgtatgtgg agctaaggaa gaccaattta
      481 tagaagttga agaagatgaa gttactttta gaaaagatac tgatgaatat ttcgtaatag
      541 taggaaatgg agcagctggt ttttatgcag cagatgctat aagaaaaaga aataaaactt
      601 gtaagataac tatgatttct aatgaagatg agttgactta ctatagacct gcactttctg
      661 atggtataaa tgaagaactt ggttcagatt tctacatgga agataaagat tggtatgata
      721 aaaataatat agtagtaata ttaggaacga atgtagataa attagatgaa gtgaataaaa
      781 ctattatagt gaatgatgga gctattaaat ttgataagct tgtaatagct acaggaagta
      841 gaaactttat accaccaatt aagggccatg atttagaaaa tgtgtttact cttagaaata
      901 taaaagattt atatagtgta aaagaagcac tagaaaaatc taagaaagtt gtagtgattg
      961 gtggcggttt attgggactt gaagctgcat gggaatttag actaaaagga ttagaagtag
     1021 tagtagttga agccatggat agcatactat caaaacaact tgataaagaa ggtagtaaaa
     1081 tattagaaca atgtgtaaga gatacaggaa tagatgtaag attgggtgta gcagttgatg
     1141 gtattgaagg tgatggaaaa gctcaaaaag ttgtatttaa agatggagat agtgtcgact
     1201 gtgatatggt agtattttca attggtgtaa gagcaaacac tcaaatggtt caggatacat
     1261 ctgtaaaaat tgatagaggt attgttgtag ataagacatt acagacaaat gttaaagata
     1321 tatatgcttg tggagatgtt gcacaagtgg gaaatattag tttagcaata tggccatctt
     1381 cagtagaaat gggaaaaata gcaggggcaa atgcaagtgg agataatttg acatttgaaa
     1441 gtgaagtata tccagtttca ttagatgcaa tgaatgtaaa agtatttagt attggtaata
     1501 tacaaaattt tgataaagaa atttcatcaa aagatgaagg tcaaagaata tataaaaaat
     1561 tatttatgaa agatggttca ttagttggag ctatacttat aaatgattta agctgtactg
     1621 ttaaattgat aagattaata tctgaaaaag gtgattttga ggatattatg aaggctgata
     1681 tactataatt taaatacatt aaaataaaaa ggagttgtct caaaattgat ttttttctaa
     1741 tcaaatttta aattcaactc cttttttgaa tttttatata aaataacatg gaaattttag
     1801 taatgtctgt ggttacatac ataggtttaa ttgtttttta tatggattgt ctctggtata
     1861 ataaattgaa ttgtgtttga ctgatagata tttttattga aagttaatac ctgttatgcg
     1921 ataataagga cgtgttaggg gagtttttat aataacaatt aatctcagtt tttgtgttcc
     1981 aatagtagca tcaacacatt ctgatgtagt agttcttttc ttataaaaat tagttacaaa
     2041 tatgcttgta attatttgat atgtaaattt accaatatta taaatgatga cctcgataat
     2101 aaggagagtg aaaaataatc tatgaacgaa aatattttga ttgtggatga tgaaaaagaa
     2161 atagcagatt taattgaagt atatttaaaa aatgaaggtt ttacagtata caagttttat
     2221 acaggtaagg aagctctaga atgtattgaa tctaaaaatt tggatatggc tattttagat
     2281 attatgcttc ctgatattga tggatttcat atttgccaga aaattcgaga aaaatactat
     2341 tatcctatca ttatgttaac agctaaaatt gaagatatag acaagataat gggtttaacc
     2401 ataggtgctg atgattatat aacaaagcca tttaaccctt tggaagttgt tgcaagagta
     2461 aagacacaat taagaagata tatgcgatat aataattctt atgaacaaca gtcgataatt
     2521 gttaatgagt atgatattaa aggattgatt atcaataaag aaacacataa atgtagttta
     2581 tttgggaaag aagtagcatt aacaccgatt gaattttcta ttctttggta tttatgtgaa
     2641 catcaaggaa aagtggttcc ttctgaagaa ttgtttgaag ctgtatgggg agaaaaatat
     2701 cttgataata ataacacagt tatggctcat atagggcgat tacgtgaaaa aattcatgaa
     2761 ccttctaaaa acccgaaatt tataaaaact gtatggggag taggttatac aattgaaaag
     2821 taaaaatatt aaagtcaatc ctgactttac tcaagtgaga aataaaattt ttatgagaac
     2881 agctttaatg gcatttatag ccattatttt catatggatt ttatattctt ttatattgta
     2941 tggtaagttt tctatctgga tagtatcatt ctttgaaaat gcttttcgta tggaatataa
     3001 agctgcattg aatttatatc agcagatttt ccgtaatagc atggagctct tcatgatact
     3061 agctatggtg attgtgtttt ttataatatt ccgggtttat ttaaattggt ttacaaaata
     3121 ttttagtgaa ataaatcaag gtattgactc tcttatcaaa gaagatgttg gagaagtggc
     3181 tttatctcca gagttattgg caatagaaaa gaaaataaac tcaattaaac atatacttga
     3241 acaacgtaaa tttgagacac aaatggcaga acaacgtaag aatgaactta ttgtttatct
     3301 tgcacatgat ttaaaaacac cacttacatc agttataggg tatctgacac tacttcgaga
     3361 tgaaagtcag atttctgaag aactgcgaaa aaaatattta tctatttcgt tggataaggc
     3421 agagcgtctt gaagatttaa ttaatgaatt ctttgaaatt acaaggttta atttatcaaa
     3481 tatatcactt gaatacagta cagtaagctt aactcgtatg cttgaacaac taacatatga
     3541 gtttaaacct actttgatga gtaagaattt aaaatataca ctgaatgtta caccaaatat
     3601 gatgataagg tgtgatgtta ataaaatgca acgtgtattt gataacttat tacgaaatgc
     3661 tgtttattat agttttgaag atactactat tgaaataaca gctgtacagg aggatgatta
     3721 tataaagctt aaatttataa atcatagcaa tacgattcca gaggaaaaac ttgagcgtat
     3781 ttttga
//
LOCUS       DAYAKB010000231         2871 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.180, whole genome shotgun sequence.
ACCESSION   DAYAKB010000231 DAYAKB010000000
VERSION     DAYAKB010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2871
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.180"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            <1..95
                     /locus_tag="ACGI3L_003868"
     CDS             <1..95
                     /locus_tag="ACGI3L_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9199501.1"
                     /translation="IGRLREKIHEPSKNPKFIKTVWGVGYTIEK"
     gene            145..1227
                     /gene="vanS"
                     /locus_tag="ACGI3L_003869"
     CDS             145..1227
                     /gene="vanS"
                     /locus_tag="ACGI3L_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFG9199502.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            1488..2588
                     /gene="vanG"
                     /locus_tag="ACGI3L_003870"
     CDS             1488..2588
                     /gene="vanG"
                     /locus_tag="ACGI3L_003870"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HFG9199503.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            2585..>2871
                     /locus_tag="ACGI3L_003871"
     CDS             2585..>2871
                     /locus_tag="ACGI3L_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9199504.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQD"
BASE COUNT         1085 a          320 c          512 g          954 t
ORIGIN      
        1 atatagggcg attacgtgaa aaaattcatg aaccttctaa aaacccgaaa tttataaaaa
       61 ctgtatgggg agtaggttat acaattgaaa agtaaaaata ttaaagtcaa tcctgacttt
      121 actcaagtga gaaataaaat ttttatgaga acagctttaa tggcatttat agccattatt
      181 ttcatatgga ttttatattc ttttatattg tatggtaagt tttctatctg gatagtatca
      241 ttctttgaaa atgcttttcg tatggaatat aaagctgcat tgaatttata tcagcagatt
      301 ttccgtaata gcatggagct cttcatgata ctagctatgg tgattgtgtt ttttataata
      361 ttccgggttt atttaaattg gtttacaaaa tattttagtg aaataaatca aggtattgac
      421 tctcttatca aagaagatgt tggagaagtg gctttatctc cagagttatt ggcaatagaa
      481 aagaaaataa actcaattaa acatatactt gaacaacgta aatttgagac acaaatggca
      541 gaacaacgta agaatgaact tattgtttat cttgcacatg atttaaaaac accacttaca
      601 tcagttatag ggtatctgac actacttcga gatgaaagtc agatttctga agaactgcga
      661 aaaaaatatt tatctatttc gttggataag gcagagcgtc ttgaagattt aattaatgaa
      721 ttctttgaaa ttacaaggtt taatttatca aatatatcac ttgaatacag tacagtaagc
      781 ttaactcgta tgcttgaaca actaacatat gagtttaaac ctactttgat gagtaagaat
      841 ttaaaatata cactgaatgt tacaccaaat atgatgataa ggtgtgatgt taataaaatg
      901 caacgtgtat ttgataactt attacgaaat gctgtttatt atagttttga agatactact
      961 attgaaataa cagctgtaca ggaggatgat tatataaagc ttaaatttat aaatcatagc
     1021 aatacgattc cagaggaaaa acttgagcgt atttttgaac aattttacag gttggataca
     1081 tctcgtaatt caaacagtgg tagagctggg ttgggacttg ctatagctaa agaaatagtg
     1141 gagcttcata acgggacaat aacagctcat agcgagaaca atataattat ctttaaggtt
     1201 attattccga ttgtaggaaa tttgtaagaa tttaagtata aaaaaatagg aaattcttta
     1261 ggataaataa ataaagagca ctcttgttat tgatataatt actgtatcaa aacaagagtg
     1321 cttttatttt gatacagtaa ttatatcaat agaaaaatgt gaaaatatat tatgtggaac
     1381 agatgcaatt gtaagtgaag gttgattgga tttgaaatag aaaaagtatt ttaacatgtt
     1441 tctgtagatt gtataaaaat aaataaatca acaaaggaga atcaaagatg aataataaaa
     1501 aaattgcagt tatatttggt ggaaactcaa cagaatatga tgtatcatta caatcagctt
     1561 ttgcagtact tgagaatttg aatacggaaa aatatgatat tataccaatt ggaattacaa
     1621 gggagggtaa ttggtatcat tatattggag attataataa tatccagaat aacacttggt
     1681 ttgaaaggga tactgatata attccagtta ttgtttcgca gaaccgtgtc aaaaatggta
     1741 ttattgaatt tttaattcct gatgctgttt ctcagaatca tattccaaat agtgctattg
     1801 aatcatgtga aaatgatatt aaatacacta aacttgattt tgtgtttcct gtactgcatg
     1861 gaaaaaatgg agaagatgga acagtgcagg ggttatttga attggcaggt atacaggtta
     1921 taggatgtgg tactctttct tcagcattat gtatggacaa agacaaatca cataaacttg
     1981 ttcattcaga aggtattaaa gtaccaaaat caatattact aaaatactca gataaattta
     2041 atgtggctga actgtcaaaa gacttaactt atccattatt tataaaacct gtgcgtgcag
     2101 gttcatcatt tggtattagt aaaatttata aaaaagaaga gttacaagta gcagtagact
     2161 tggcttttga acatgataat gaagtaataa ttgaggaaaa tattgatggt tttgaggtag
     2221 ggtgtgcagt tttaggaaac gatgacttac ttgttggaag agtagatgaa atagaattgt
     2281 caaaaggatt ttttgattat acagaaaaat atacattgaa aagttcaaaa attcatatgc
     2341 cagctagaat tgatttggat tgtgagaaaa gaatacaaga gacagcaaaa attatttata
     2401 gaactcttgg atgttctgga tttgctagag tagatatgtt tttaactcca tctggtgaaa
     2461 ttatttttaa tgaagtcaat acaattcctg gctttacttc tcatagtcgt tatccaaata
     2521 tgatgaaagg tattggattg tcttttgaag aaatattgga caagataatt gaggtgtaca
     2581 taaaatgatg aataatattt tattagataa aaataaagaa gataaaatga caaatactat
     2641 cttattgact aaagataaag tttatgatgg gaatctaatt ctagtaaatg cttttttacc
     2701 agttaaaaca tctgaagata tagatttaat tcctgtagat acaaggtttc caagtattct
     2761 tatgaaacgt gaagctacaa acattttaca aaatatttta aaaagtatat gtggaataaa
     2821 tgaaatagta cctgtaagtg gatatcgtac tgcagaggaa caacaagata t
//
LOCUS       DAYAKB010000232         1820 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate IP-e-D19MD036
            SAMN40601692-rid21575723.guided.196, whole genome shotgun sequence.
ACCESSION   DAYAKB010000232 DAYAKB010000000
VERSION     DAYAKB010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601692
            Sequence Read Archive: SRR28438798
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157554.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157554.1
            Genome Coverage       :: 60x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:01:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,873
            CDSs (total)                      :: 3,796
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 7 of 31
            Pseudo Genes (incomplete)         :: 23 of 31
            Pseudo Genes (internal stop)      :: 11 of 31
            Pseudo Genes (multiple problems)  :: 8 of 31
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601692-rid21575723.guided.196"
                     /isolate="IP-e-D19MD036"
                     /isolation_source="Manure (Cattle)"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2019"
                     /collected_by="Institute Pasteur"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="ACGI3L_003872"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="ACGI3L_003872"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HFG9199505.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..>1820
                     /locus_tag="ACGI3L_003873"
     CDS             1575..>1820
                     /locus_tag="ACGI3L_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9199506.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVF"
BASE COUNT          754 a          158 c          299 g          609 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacttaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt
//
